Sample records for tail disease wtd

  1. Goats are a potential reservoir for the herpesvirus (MCFV-WTD),causing malignant catarrhal fever in deer

    USDA-ARS?s Scientific Manuscript database

    In the recent investigation of malignant catarrhal fever (MCF) in a red brocket deer (Mazama americana) from a Texas zoo, the MCF viral DNA from the newly recognized herpesvirus causing disease in white-tailed deer (Odocoileus virginianus) (termed MCFV-WTD) was detected. The epidemiology information...

  2. Scrapie transmits to white-tailed deer by the oral route and has a molecular profile similar to chronic wasting disease

    USDA-ARS?s Scientific Manuscript database

    The purpose of this work was to determine susceptibility of white-tailed deer (WTD) to the agent of sheep scrapie and to compare the resultant PrPSc to that of the original inoculum and chronic wasting disease (CWD). We inoculated WTD by a natural route of exposure (concurrent oral and intranasal (I...

  3. Susceptibility of white-tailed deer (Odocoileus virginianus) to experimental infection with epizootic hemorrhagic disease virus serotype 7.

    PubMed

    Ruder, Mark G; Allison, Andrew B; Stallknecht, David E; Mead, Daniel G; McGraw, Sabrina M; Carter, Deborah L; Kubiski, Steven V; Batten, Carrie A; Klement, Eyal; Howerth, Elizabeth W

    2012-07-01

    During the fall of 2006, in Israel, epizootic hemorrhagic disease virus (EHDV) serotype 7 caused an intense and widespread epizootic in domestic cattle that resulted in significant economic losses for the dairy industry. The susceptibility of potential North American vector and ruminant hosts to infection with EHDV-7 is not known but is essential to understanding the potential for establishment of this exotic orbivirus in North America if it were introduced. Our primary objective was to determine whether white-tailed deer (WTD; Odocoileus virginianus) are susceptible to infection with EHDV-7. Six, 8-mo-old WTD were experimentally infected with EHDV-7, and all became infected and exhibited varying degrees of clinical disease. Clinical signs, clinicopathologic abnormalities, and postmortem findings were consistent with previous reports of orbiviral hemorrhagic disease (HD) in this species. Four of six animals died or were euthanized because of the severity of disease, one on postinoculation day (PID) 5 and the remaining WTD on PID 7. All deer had detectable viremia on PID 3, which peaked on PID 5 or 6 and persisted for as long as PID 46 in one animal. Deer surviving the acute phase of the disease seroconverted by PID 10. Based on the 67% mortality rate we observed, this strain of EHDV-7 is virulent in WTD, reaffirming their role as a sentinel species for the detection of endemic and nonendemic EHDV. Further, the observed disease was indistinguishable from previous reports of disease caused by North American EHDV and bluetongue virus serotypes, highlighting the importance of serotype-specific diagnostics during suspected HD outbreaks.

  4. Anatomical distribution of Mycobacterium bovis genotypes in experimentally infected white-tailed deer

    USDA-ARS?s Scientific Manuscript database

    Mycobacterium bovis (M. bovis) causes tuberculosis in white-tailed deer (WTD). Natural infection of WTD with M. bovis is most closely mimicked by instilling inoculum into palatine tonsilar crypts. One hundred fifty days after intratonsilar inoculation, M. bovis was cultured from 30 tissues originati...

  5. A Nonluminescent and Highly Virulent Vibrio harveyi Strain Is Associated with “Bacterial White Tail Disease” of Litopenaeus vannamei Shrimp

    PubMed Central

    Zhou, Junfang; Fang, Wenhong; Yang, Xianle; Zhou, Shuai; Hu, Linlin; Li, Xincang; Qi, Xinyong; Su, Hang; Xie, Layue

    2012-01-01

    Recurrent outbreaks of a disease in pond-cultured juvenile and subadult Litopenaeus vannamei shrimp in several districts in China remain an important problem in recent years. The disease was characterized by “white tail” and generally accompanied by mass mortalities. Based on data from the microscopical analyses, PCR detection and 16S rRNA sequencing, a new Vibrio harveyi strain (designated as strain HLB0905) was identified as the etiologic pathogen. The bacterial isolation and challenge tests demonstrated that the HLB0905 strain was nonluminescent but highly virulent. It could cause mass mortality in affected shrimp during a short time period with a low dose of infection. Meanwhile, the histopathological and electron microscopical analysis both showed that the HLB0905 strain could cause severe fiber cell damages and striated muscle necrosis by accumulating in the tail muscle of L. vannamei shrimp, which led the affected shrimp to exhibit white or opaque lesions in the tail. The typical sign was closely similar to that caused by infectious myonecrosis (IMN), white tail disease (WTD) or penaeid white tail disease (PWTD). To differentiate from such diseases as with a sign of “white tail” but of non-bacterial origin, the present disease was named as “bacterial white tail disease (BWTD)”. Present study revealed that, just like IMN and WTD, BWTD could also cause mass mortalities in pond-cultured shrimp. These results suggested that some bacterial strains are changing themselves from secondary to primary pathogens by enhancing their virulence in current shrimp aquaculture system. PMID:22383954

  6. Occurrence, isolation, and genetic characterization of Toxoplasma gondii from white tailed deer (Odocoileus virginianus) in New Jersey

    USDA-ARS?s Scientific Manuscript database

    White tailed deer (WTD) is an important reservoir host for Toxoplasma gondii. Each yr hundreds of thousands WTD are hunted or die in road accidents in the U.S.A. Humans and animals can become infected with T. gondii by eating infected venison. Wild felids that eat infected deer tissues can shed oocy...

  7. Vector competence of Culicoides sonorensis (Diptera: Ceratopogonidae) to epizootic hemorrhagic disease virus serotype 7.

    PubMed

    Ruder, Mark G; Howerth, Elizabeth W; Stallknecht, David E; Allison, Andrew B; Carter, Deborah L; Drolet, Barbara S; Klement, Eyal; Mead, Daniel G

    2012-10-17

    Culicoides sonorensis (Diptera: Ceratopogonidae) is a vector of epizootic hemorrhagic disease virus (EHDV) serotypes 1 and 2 in North America, where these viruses are well-known pathogens of white-tailed deer (WTD) and other wild ruminants. Although historically rare, reports of clinical EHDV infection in cattle have increased in some parts of the world over the past decade. In 2006, an EHDV-7 epizootic in cattle resulted in economic loss for the Israeli dairy industry. White-tailed deer are susceptible to EHDV-7 infection and disease; however, this serotype is exotic to the US and the susceptibility of C. sonorensis to this cattle-virulent EHDV is not known. The objective of the study was to determine if C. sonorensis is susceptible to EHDV-7 infection and is a competent vector. To evaluate the susceptibility of C. sonorensis, midges were fed on EHDV-7 infected WTD, held at 22 ± 1°C, and processed individually for virus isolation and titration on 4-16 days post feeding (dpf). Midges with a virus titer of ≥ 10(2.7) median tissue culture infective doses (TCID(50))/midge were considered potentially competent. To determine if infected C. sonorensis were capable of transmitting EHDV-7 to a host, a susceptible WTD was then fed on by a group of 14-16 dpf midges. From 4-16 dpf, 45% (156/350) of midges that fed on WTD with high titer viremia (>10(7) TCID(50)/ml) were virus isolation-positive, and starting from 10-16 dpf, 32% (35/109) of these virus isolation-positive midges were potentially competent (≥ 10(2.7) TCID(50)/midge). Midges that fed on infected deer transmitted the virus to a susceptible WTD at 14-16 dpf. The WTD developed viremia and severe clinical disease. This study demonstrates that C. sonorensis is susceptible to EHDV-7 infection and can transmit the virus to susceptible WTD, thus, C. sonorensis should be considered a potential vector of EHDV-7. Together with previous work, this study demonstrates that North America has a susceptible ruminant and

  8. Epidemiology of toxoplasmosis in white tailed deer (Odocoileus virginianus): occurrence, congenital transmission, correlates of infection, isolation, and genetic characterization of Toxoplasma gondii

    USDA-ARS?s Scientific Manuscript database

    The prevalence of Toxoplasma gondii in white tailed deer (WTD) in the USA is high, but little is known of the epidemiology of toxoplasmosis in this host. In the present study, we compared T. gondii seroprevalence from 531 WTD collected in 2012 and 2013 from a Metropolitan Park in Ohio, and and 485 W...

  9. Enterocytozoon bieneusi, Giardia and Cryptosporidium infecting white-tailed deer

    USDA-ARS?s Scientific Manuscript database

    Despite a white-tailed deer (WTD) population in the United States of approximately 32 million animals extremely little is known of the prevalence and species of the protists that infect these animals. The present study was undertaken to determine the presence of potential human protist pathogens in ...

  10. Vector competence of Culicoides sonorensis (Diptera: Ceratopogonidae) to epizootic hemorrhagic disease virus serotype 7

    USDA-ARS?s Scientific Manuscript database

    Background: Culicoides sonorensis (Diptera: Ceratopogonidae) is a vector of epizootic hemorrhagic disease virus (EHDV) serotypes 1 and 2 in North America, where these viruses are well-known pathogens of white-tailed deer (WTD) and other wild ruminants. Although historically rare, reports of clinica...

  11. Host and Potential Vector Susceptibility to an Emerging Orbivirus in the United States: Epizootic Hemorrhagic Disease Virus Serotype 6.

    PubMed

    Ruder, M G; Stallknecht, D E; Allison, A B; Mead, D G; Carter, D L; Howerth, E W

    2016-05-01

    Epizootic hemorrhagic disease viruses (EHDVs) are orbiviruses transmitted by Culicoides biting midges to domestic and wild ruminants. EHDV-1 and EHDV-2 are endemic in the United States, where epizootic hemorrhagic disease is the most significant viral disease of white-tailed deer (WTD;Odocoileus virginianus) and reports of epizootic hemorrhagic disease in cattle are increasing. In 2006, a reassortant EHDV-6 was isolated from dead WTD in Indiana and has been detected each subsequent year over a wide geographic region. Since EHDV-6 is not a historically endemic serotype in the United States, it is important to understand infection outcome in potential hosts. Specifically, we aimed to evaluate the pathogenicity of the virus in 2 primary US ruminant hosts (WTD and cattle) and the susceptibility of a confirmed US vector (Culicoides sonorensis). Five WTD and 4 cattle were inoculated with >10(6)TCID50EHDV-6 by intradermal and subcutaneous injection. All 5 WTD exhibited moderate to severe disease, and 3 died. Viremia was first detected 3 to 5 days postinfection (dpi) with surviving animals seroconverting by 10 dpi. Two of 4 inoculated cattle had detectable viremia, 5 to 10 dpi and 7 to 24 dpi, respectively. No clinical, hematologic, or pathologic abnormalities were observed. Antibodies were detected by 10 dpi in 3 of 4 cows.C. sonorensis were fed on WTD blood spiked with EHDV-6 and held for 4 to 14 days postfeeding at 25°C. From 4 to 14 days postfeeding, 19 of 171 midges were virus isolation positive and 6 of 171 had ≥10(2.7)TCID50EHDV-6. Although outcomes varied, these studies demonstrate the susceptibility of ruminant and vector hosts in the United States for this recently emerged EHDV serotype. © The Author(s) 2015.

  12. Comparative daily activity patterns of Nilgai, Boselaphus tragocamelus and white-tailed deer, Odocoileus virginianus in South Texas

    USDA-ARS?s Scientific Manuscript database

    Nilgai antelope, Boselaphus tragocamelus, and white-tailed deer (WTD), Odocoileus virginianus, are hosts of the cattle fever ticks, Rhipicephalus (Boophilus) microplus, and R. (B.) annulatus in south Texas. Daily activity patterns were studied to develop optimum timing for field treatment methods fo...

  13. Head space analysis to non-invasively distinguish between vaccinated and bovine tuberculosis-infected white-tailed deer

    USDA-ARS?s Scientific Manuscript database

    White-tailed deer (WTD; Odocoileus virginianus) can act as a reservoir for bovine tuberculosis (bTB), caused by Mycobacterium bovis, and can be a source of infection in cattle. Presently, no method exists to noninvasively monitor the presence of bTB in wildlife. In addition, due to similarities betw...

  14. Transmission of the agent of sheep scrapie to deer results in PrPSc with two distinct molecular profiles

    USDA-ARS?s Scientific Manuscript database

    The purpose of this work was to determine susceptibility of white-tailed deer (WTD) to the agent of sheep scrapie and to compare the resultant PrPSc to that of the original inoculum and chronic wasting disease (CWD). We inoculated WTD by a natural route of exposure (concurrent oral and intranasal (I...

  15. Occurrence, isolation, and genetic characterization of Toxoplasma gondii from white-tailed deer (Odocoileus virginianus) in New Jersey.

    PubMed

    Dubey, J P; Randall, A R; Choudhary, S; Ferreira, L R; Verma, S K; Oliveira, S; Kwok, O C H; Su, C

    2013-10-01

    The ingestion of uncooked infected white-tailed deer (WTD) tissues can transmit Toxoplasma gondii infection to humans and mesocarnivores, including cats. In the present study, we tested 264 WTD from New Jersey for T. gondii infection during the 2011-2012 hunting season. Serum samples were tested for antibodies to T. gondii by the modified agglutination test (cutoff titer, 25); 76 (28.7%) of 264 WTD were seropositive. Heart muscle samples from 64 seropositive WTD were digested in pepsin, and the digests were bioassayed for the isolation of T. gondii . Viable T. gondii was isolated in mice from the myocardium of 9 WTD; tachyzoites from infected mouse tissues were further propagated in cell culture. One of the 9 strains was highly virulent for outbred Swiss Webster mice. The DNA isolated from culture-derived tachyzoites of these 9 T. gondii isolates was characterized using 11 PCR-RFLP markers (SAG1, 5'- and 3'-SAG2, alt.SAG2, SAG3, BTUB, GRA6, c22-8, c29-2, L358, PK1, and Apico). Six genotypes were found, including ToxoDB genotype no. 2 (Type III), no. 3 (Type II variant), no. 4 (Type 12), no. 216, no. 220, and no. 221. The last 2 were new genotypes that were reported for the first time. This is the first report of T. gondii infection in deer from this region of the United States.

  16. Morphologic and Molecular Characterization of a Demodex (Acari: Demodicidae) Species from White-Tailed Deer (Odocoileus virginianus)

    PubMed Central

    Yabsley, Michael J.; Clay, Sarah E.; Gibbs, Samantha E. J.; Cunningham, Mark W.; Austel, Michaela G.

    2013-01-01

    Demodex mites, although usually nonpathogenic, can cause a wide range of dermatological lesions ranging from mild skin irritation and alopecia to severe furunculosis. Recently, a case of demodicosis from a white-tailed deer (Odocoileus virginianus) revealed a Demodex species morphologically distinct from Demodex odocoilei. All life cycle stages were considerably larger than D. odocoilei and although similar in size to D. kutzeri and D. acutipes from European cervids, numerous morphometrics distinguished the four species. Adult males and females were 209.1 ± 13.1 and 225.5 ± 13.4 μm in length, respectively. Ova, larva, and nymphs measured 65.1 ± 4.1, 124.9 ± 11.6, and 205.1 ± 19.4 μm in length, respectively. For phylogenetic analyses, a portion of the 18S rRNA gene was amplified and sequenced from samples of the WTD Demodex sp., two Demodex samples from domestic dogs, and Demodex ursi from a black bear. Phylogenetic analyses indicated that the WTD Demodex was most similar to D. musculi from laboratory mice. A partial sequence from D. ursi was identical to the WTD Demodex sequence; however, these two species can be differentiated morphologically. This paper describes a second Demodex species from white-tailed deer and indicates that 18S rRNA is useful for phylogenetic analysis of most Demodex species, but two morphologically distinct species had identical partial sequences. Additional gene targets should be investigated for phylogenetic and parasite-host association studies. PMID:27335854

  17. Seroprevalence of toxoplasma gondii in white-tailed deer and free-roaming cats across a suburban to urban gradient in northeastern Ohio

    USDA-ARS?s Scientific Manuscript database

    Toxoplasma gondii is an obligate zoonotic protozoan parasite infecting a variety of animals. White-tailed deer-(WTD, Odocoileus virginianus) serve as both a potential source for human infection as well as indicators of environmental risk factors for exposure to T. gondii. Here we determine the serop...

  18. Modeling the impact of climate and landscape on the efficacy of white tailed deer vaccination for cattle tick control in northeastern Mexico.

    PubMed

    Estrada-Peña, Agustín; Carreón, Diana; Almazán, Consuelo; de la Fuente, José

    2014-01-01

    Cattle ticks are distributed worldwide and affect animal health and livestock production. White tailed deer (WTD) sustain and spread cattle tick populations. The aim of this study was to model the efficacy of anti-tick vaccination of WTD to control tick infestations in the absence of cattle vaccination in a territory where both host species coexist and sustain cattle tick populations. Agent-based models that included land cover/landscape properties (patch size, distances to patches) and climatic conditions were built in a GIS environment to simulate WTD vaccine effectiveness under conditions where unvaccinated cattle shared the landscape. Published and validated information on tick life cycle was used to build models describing tick mortality and developmental rates. Data from simulations were applied to a large territory in northeastern Mexico where cattle ticks are endemic and WTD and cattle share substantial portions of the habitat. WTD movements were simulated together with tick population dynamics considering the actual landscape and climatic features. The size of the vegetation patches and the distance between patches were critical for the successful control of tick infestations after WTD vaccination. The presence of well-connected, large vegetation patches proved essential for tick control, since the tick could persist in areas of highly fragmented habitat. The continued application of one yearly vaccination on days 1-70 for three years reduced tick abundance/animal/patch by a factor of 40 and 60 for R. annulatus and R. microplus, respectively when compared to non-vaccinated controls. The study showed that vaccination of WTD alone during three consecutive years could result in the reduction of cattle tick populations in northeastern Mexico. Furthermore, the results of the simulations suggested the possibility of using vaccines to prevent the spread and thus the re-introduction of cattle ticks into tick-free areas.

  19. Comparison of natural and artificial odor lures for nilgai (Boselaphus tragocamelus) and white-tailed deer (Odocoileus virginianus) in South Texas: developing treatment for cattle fever tick eradication

    USDA-ARS?s Scientific Manuscript database

    Cattle fever ticks (CFT), vectors of bovine babesiosis and anaplasmosis, were eradicated from the United States by 1943, but are frequently reintroduced from neighboring border states of Mexico via stray cattle and wildlife hosts including white-tailed deer (Odocoileus virginianus) (WTD) and nilgai ...

  20. Sea level and ground water table depth (WTD): A biogeochemical pacemaker for glacial-interglacial cycling

    NASA Astrophysics Data System (ADS)

    Cowling, S. A.

    2016-11-01

    The role that changes in sea level have on potential carbon-climate feedbacks are discussed as a potential contributing mechanism for terminating glacial periods. Focus will be on coastal wetlands because these systems can be substantially altered by changing sea level and ground water table depth (WTD); in addition to being important moderators of the exchange of nutrients and energy between terrestrial and marine ecosystems. A hypothesis is outlined that describes how the release of carbon from formerly anaerobic wetland soils and sediments can influence climate when sea levels begin to decline. As ground WTD deepens and eventually recedes from the surface, coastal wetland basins may become isolated from their belowground source of water. With their primary source of base flow removed, coastal wetlands likely dried up, promoting decomposition of the carbon compounds buried in their sediments. Depending on the timing of basin isolation and the timing of decomposition, glacial sea level lows could have triggered a relatively large positive carbon feedback on climate warming, just at the time when a new interglacial period is about to begin.

  1. Evaluating use of cattle winter feeding areas by elk and white-tailed deer: implications for managing bovine tuberculosis transmission risk from the ground up.

    PubMed

    Brook, Ryan K; Wal, Eric Vander; van Beest, Floris M; McLachlan, Stéphane M

    2013-02-01

    Transmission of bovine tuberculosis (Mycobacterium bovis) among wildlife and livestock has created important risks for conservation and agriculture. Management strategies aimed at controlling TB have typically been top-down, regionally focused, and government-led programs that were at best only partially successful. The purpose of this study was to quantify co-mingling of elk and white-tailed deer (WTD) with cattle at multiple spatial scales (i.e., the regional farm scale and winter cattle feeding area patch) in southwestern Manitoba, Canada, to assess the potential for bovine tuberculosis transmission and identify alternative management strategies. For each spatial scale we quantified use of cattle farms by elk and white-tailed deer. We mailed questionnaires to rural households and then conducted personal interviews with 86 cattle farmers to map the spatial distribution of their cattle winter feeding areas at a fine scale. We deployed Global Positioning System (GPS) collars on 48 wild elk and 16 wild white-tailed deer from 2003 to 2011. Elk were observed on farms by 66% of cattle producers, including 5% and 20% who observed direct and indirect contact, respectively, between elk and cattle. Cattle producers consistently (≈100%) observed white-tailed deer on their farms, including 11% and 47% whom observed direct and indirect contact, respectively, between white-tailed deer and cattle. A higher probability of white-tailed deer-cattle contact at the regional scale occurs on farms that (1) left crop residues specifically for wildlife, (2) had larger cattle herds, (3) used round bale feeders, and (4) were farther away from protected areas. None of the GPS-collared elk locations overlapped with cattle winter feeding areas. In contrast, 21% of GPS-collared white-tailed deer locations overlapped with winter cattle winter feeding areas (22% of these were from male WTD and 78% were from female WTD). White-tailed deer selected cattle winter feeding areas with higher (1

  2. Study on thermal properties and crystallization behavior of electron beam irradiated ethylene vinyl acetate (EVA)/waste tyre dust (WTD) blends in the presence of polyethylene graft maleic anhydride (PEgMAH)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ramli, Syuhada; Ahmad, S. H.; Ratnam, C. T.

    2013-11-27

    The aim of this article is to show the effects of the electron beam irradiation dose and presence of a compatibiliser on the thermal properties and crystallinity of EVA/WTD blends. The purpose of applying electron beam radiation with doses range 50 to 200 kGy and adding a compatibiliser was to enhance the compatibility of the studied blends and at the same time to investigate the possibility of using this technique in the process of recycling polymeric materials. As the compatibilisers, the polyethylene grafted maleic anhydride (PEgMAH) was utilized, they were added at the amounts of 1-5 phr respectively. The enhancementmore » of thermal properties was accompanied by the following effects, discussed in this article: i) an irradiated EVA/WTD blend at 200kGy was found to improve the thermal properties of EVA, ii) the addition of PEgMAH in EVA/WTD blends and the subsequent irradiation allowed prevention of degradation mechanism. iii) the ΔH{sub f} and crystallinity percentage decrease at higher PEgMAH content.« less

  3. Will Culling White-Tailed Deer Prevent Lyme Disease?

    PubMed

    Kugeler, K J; Jordan, R A; Schulze, T L; Griffith, K S; Mead, P S

    2016-08-01

    White-tailed deer play an important role in the ecology of Lyme disease. In the United States, where the incidence and geographic range of Lyme disease continue to increase, reduction of white-tailed deer populations has been proposed as a means of preventing human illness. The effectiveness of this politically sensitive prevention method is poorly understood. We summarize and evaluate available evidence regarding the effect of deer reduction on vector tick abundance and human disease incidence. Elimination of deer from islands and other isolated settings can have a substantial impact on the reproduction of blacklegged ticks, while reduction short of complete elimination has yielded mixed results. To date, most studies have been conducted in ecologic situations that are not representative to the vast majority of areas with high human Lyme disease risk. Robust evidence linking deer control to reduced human Lyme disease risk is lacking. Currently, there is insufficient evidence to recommend deer population reduction as a Lyme disease prevention measure, except in specific ecologic circumstances. © 2015 Blackwell Verlag GmbH.

  4. Will Culling White-Tailed Deer Prevent Lyme Disease?

    PubMed Central

    Kugeler, K. J.; Jordan, R. A.; Schulze, T. L.; Griffith, K. S.; Mead, P. S.

    2015-01-01

    Summary White-tailed deer play an important role in the ecology of Lyme disease. In the United States, where the incidence and geographic range of Lyme disease continue to increase, reduction of white-tailed deer populations has been proposed as a means of preventing human illness. The effectiveness of this politically sensitive prevention method is poorly understood. We summarize and evaluate available evidence regarding the effect of deer reduction on vector tick abundance and human disease incidence. Elimination of deer from islands and other isolated settings can have a substantial impact on the reproduction of blacklegged ticks, while reduction short of complete elimination has yielded mixed results. To date, most studies have been conducted in ecologic situations that are not representative to the vast majority of areas with high human Lyme disease risk. Robust evidence linking deer control to reduced human Lyme disease risk is lacking. Currently, there is insufficient evidence to recommend deer population reduction as a Lyme disease prevention measure, except in specific ecologic circumstances. PMID:26684932

  5. Using White-tailed Deer (Odocoileus virginianus) in Infectious Disease Research

    PubMed Central

    Palmer, Mitchell V; Cox, Rebecca J; Waters, W Ray; Thacker, Tyler C; Whipple, Diana L

    2017-01-01

    Between 1940 and 2004, more than 335 emerging infectious disease events were reported in the scientific literature. The majority (60%) of these events involved zoonoses, most of which (72%) were of wildlife origin or had an epidemiologically important wildlife host. Because this trend of increasing emerging diseases likely will continue, understanding the pathogenesis, transmission, and diagnosis of these diseases in the relevant wildlife host is paramount. Achieving this goal often requires using wild animals as research subjects, which are vastly different from the traditional livestock or laboratory animals used by most universities and institutions. Using wildlife in infectious disease research presents many challenges but also provides opportunities to answer questions impossible to address by using traditional models. Cervid species, especially white-tailed deer (Odocoileus virginianus), elk (Cervus canadensis), and red deer (Cervus elaphus), are hosts or sentinels for several important pathogens, some of which are zoonotic. The long history of infectious disease research using white-tailed deer, conducted at ever-increasing levels of sophisticated biosecurity, demonstrates that this type of research can be conducted safely and that valuable insights can be gained. The greatest challenges to using wildlife in infectious disease research include animal source, facility design, nutrition, animal handling, and enrichment and other practices that both facilitate animal care and enhance animal wellbeing. The study of Mycobacterium bovis infection in white-tailed deer at the USDA's National Animal Disease Center serves to illustrate one approach to address these challenges. PMID:28724483

  6. Chronic wasting disease in free-ranging Wisconsin white-tailed deer

    USGS Publications Warehouse

    Joly, D.O.; Ribic, C.A.; Langenberg, J.A.; Beheler, K.; Batha, C.A.; Dhuey, B.J.; Rolley, R.E.; Bartelt, G.; VanDeelen, T.R.; Samuel, M.D.

    2003-01-01

    Three White-tailed Deer shot within 5 km during the 2001 hunting season in Wisconsin tested positive for chronic wasting disease, a prion disease of cervids. Subsequent sampling within 18 km showed a 3% prevalence (n=476). This discovery represents an important range extension for chronic wasting disease into the eastern United States.

  7. Chronic wasting disease drives population decline of white-tailed deer

    USGS Publications Warehouse

    Edmunds, David; Kauffman, Matthew J.; Schumaker, Brant; Lindzey, Frederick G.; Cook, Walter; Kreeger, Terry J.; Grogan, Ronald; Cornish, Todd

    2016-01-01

    Chronic wasting disease (CWD) is an invariably fatal transmissible spongiform encephalopathy of white-tailed deer, mule deer, elk, and moose. Despite a 100% fatality rate, areas of high prevalence, and increasingly expanding geographic endemic areas, little is known about the population-level effects of CWD in deer. To investigate these effects, we tested the null hypothesis that high prevalence CWD did not negatively impact white-tailed deer population sustainability. The specific objectives of the study were to monitor CWD-positive and CWD-negative white-tailed deer in a high-prevalence CWD area longitudinally via radio-telemetry and global positioning system (GPS) collars. For the two populations, we determined the following: a) demographic and disease indices, b) annual survival, and c) finite rate of population growth (λ). The CWD prevalence was higher in females (42%) than males (28.8%) and hunter harvest and clinical CWD were the most frequent causes of mortality, with CWD-positive deer over-represented in harvest and total mortalities. Survival was significantly lower for CWD-positive deer and separately by sex; CWD-positive deer were 4.5 times more likely to die annually than CWD-negative deer while bucks were 1.7 times more likely to die than does. Population λ was 0.896 (0.859–0.980), which indicated a 10.4% annual decline. We show that a chronic disease that becomes endemic in wildlife populations has the potential to be population-limiting and the strong population-level effects of CWD suggest affected populations are not sustainable at high disease prevalence under current harvest levels.

  8. Primary transmission of chronic wasting disease versus scrapie prions from small ruminants to transgenic mice expressing ovine or cervid prion protein.

    PubMed

    Madsen-Bouterse, Sally A; Schneider, David A; Zhuang, Dongyue; Dassanayake, Rohana P; Balachandran, Aru; Mitchell, Gordon B; O'Rourke, Katherine I

    2016-09-01

    Development of mice expressing either ovine (Tg338) or cervid (TgElk) prion protein (PrP) have aided in characterization of scrapie and chronic wasting disease (CWD), respectively. Experimental inoculation of sheep with CWD prions has demonstrated the potential for interspecies transmission but, infection with CWD versus classical scrapie prions may be difficult to differentiate using validated diagnostic platforms. In this study, mouse bioassay in Tg338 and TgElk was utilized to evaluate transmission of CWD versus scrapie prions from small ruminants. Mice (≥5 per homogenate) were inoculated with brain homogenates from clinically affected sheep or goats with naturally acquired classical scrapie, white-tailed deer with naturally acquired CWD (WTD-CWD) or sheep with experimentally acquired CWD derived from elk (sheep-passaged-CWD). Survival time (time to clinical disease) and attack rates (brain accumulation of protease resistant PrP, PrPres) were determined. Inoculation with classical scrapie prions resulted in clinical disease and 100 % attack rates in Tg338, but no clinical disease at endpoint (>300 days post-inoculation, p.i.) and low attack rates (6.8 %) in TgElk. Inoculation with WTD-CWD prions yielded no clinical disease or brain PrPres accumulation in Tg338 at endpoint (>500 days p.i.), but rapid onset of clinical disease (~121 days p.i.) and 100 % attack rate in TgElk. Sheep-passaged-CWD resulted in transmission to both mouse lines with 100 % attack rates at endpoint in Tg338 and an attack rate of ~73 % in TgElk with some culled due to clinical disease. These primary transmission observations demonstrate the potential of bioassay in Tg338 and TgElk to help differentiate possible infection with CWD versus classical scrapie prions in sheep and goats.

  9. Disease limits populations: plague and black-tailed prairie dogs

    USGS Publications Warehouse

    Cully, Jack F.; Johnson, T.; Collinge, S.K.; Ray, C.

    2010-01-01

    Plague is an exotic vector-borne disease caused by the bacterium Yersinia pestis that causes mortality rates approaching 100% in black-tailed prairie dogs (Cynomys ludovicianus). We mapped the perimeter of the active portions of black-tailed prairie dog colonies annually between 1999 and 2005 at four prairie dog colony complexes in areas with a history of plague, as well as at two complexes that were located outside the distribution of plague at the time of mapping and had therefore never been affected by the disease. We hypothesized that the presence of plague would significantly reduce overall black-tailed prairie dog colony area, reduce the sizes of colonies on these landscapes, and increase nearest-neighbor distances between colonies. Within the region historically affected by plague, individual colonies were smaller, nearest-neighbor distances were greater, and the proportion of potential habitat occupied by active prairie dog colonies was smaller than at plague-free sites. Populations that endured plague were composed of fewer large colonies (>100 ha) than populations that were historically plague free. We suggest that these differences among sites in colony size and isolation may slow recolonization after extirpation. At the same time, greater intercolony distances may also reduce intercolony transmission of pathogens. Reduced transmission among smaller and more distant colonies may ultimately enhance long-term prairie dog population persistence in areas where plague is present.

  10. Disease limits populations: plague and black-tailed prairie dogs.

    PubMed

    Cully, Jack F; Johnson, Tammi L; Collinge, Sharon K; Ray, Chris

    2010-01-01

    Plague is an exotic vector-borne disease caused by the bacterium Yersinia pestis that causes mortality rates approaching 100% in black-tailed prairie dogs (Cynomys ludovicianus). We mapped the perimeter of the active portions of black-tailed prairie dog colonies annually between 1999 and 2005 at four prairie dog colony complexes in areas with a history of plague, as well as at two complexes that were located outside the distribution of plague at the time of mapping and had therefore never been affected by the disease. We hypothesized that the presence of plague would significantly reduce overall black-tailed prairie dog colony area, reduce the sizes of colonies on these landscapes, and increase nearest-neighbor distances between colonies. Within the region historically affected by plague, individual colonies were smaller, nearest-neighbor distances were greater, and the proportion of potential habitat occupied by active prairie dog colonies was smaller than at plague-free sites. Populations that endured plague were composed of fewer large colonies (>100 ha) than populations that were historically plague free. We suggest that these differences among sites in colony size and isolation may slow recolonization after extirpation. At the same time, greater intercolony distances may also reduce intercolony transmission of pathogens. Reduced transmission among smaller and more distant colonies may ultimately enhance long-term prairie dog population persistence in areas where plague is present.

  11. Disease Limits Populations: Plague and Black-Tailed Prairie Dogs

    PubMed Central

    Johnson, Tammi L.; Collinge, Sharon K.; Ray, Chris

    2010-01-01

    Abstract Plague is an exotic vector-borne disease caused by the bacterium Yersinia pestis that causes mortality rates approaching 100% in black-tailed prairie dogs (Cynomys ludovicianus). We mapped the perimeter of the active portions of black-tailed prairie dog colonies annually between 1999 and 2005 at four prairie dog colony complexes in areas with a history of plague, as well as at two complexes that were located outside the distribution of plague at the time of mapping and had therefore never been affected by the disease. We hypothesized that the presence of plague would significantly reduce overall black-tailed prairie dog colony area, reduce the sizes of colonies on these landscapes, and increase nearest-neighbor distances between colonies. Within the region historically affected by plague, individual colonies were smaller, nearest-neighbor distances were greater, and the proportion of potential habitat occupied by active prairie dog colonies was smaller than at plague-free sites. Populations that endured plague were composed of fewer large colonies (>100 ha) than populations that were historically plague free. We suggest that these differences among sites in colony size and isolation may slow recolonization after extirpation. At the same time, greater intercolony distances may also reduce intercolony transmission of pathogens. Reduced transmission among smaller and more distant colonies may ultimately enhance long-term prairie dog population persistence in areas where plague is present. PMID:20158327

  12. Evaluation of Serodiagnostic Assays for Mycobacterium bovis Infection in Elk, White-Tailed Deer, and Reindeer in the United States

    PubMed Central

    Nelson, Jeffrey T.; Orloski, Kathleen A.; Lloyd, Audra L.; Camacho, Mark; Schoenbaum, Mark A.; Robbe-Austerman, Suelee; Thomsen, Bruce V.; Hall, S. Mark

    2012-01-01

    In 2011, the United States Department of Agriculture conducted a project in which elk (Cervus elaphus spp.), white-tailed deer (WTD) (Odocoileus virginianus), and reindeer (Rangifer tarandus) were evaluated by the single cervical tuberculin test (SCT), comparative cervical tuberculin test (CCT), and serologic tests. The rapid antibody detection tests evaluated were the CervidTB Stat-Pak (Stat-Pak), and the Dual Path Platform VetTB (DPP). Blood was collected from presumably uninfected animals prior to tuberculin injection for the SCT. A total of 1,783 animals were enrolled in the project. Of these, 1,752 (98.3%) were classified as presumably uninfected, based on originating from a captive cervid herd with no history of exposure to TB. Stat-Pak specificity estimates were 92.4% in reindeer, 96.7% in WTD, and 98.3% in elk and were not significantly different from SCT specificity estimates. Using the DPP in series on Stat-Pak antibody-positive samples improved specificity in the three species. Thirty one animals were classified as confirmed infected, based on necropsy and laboratory results, and 27/31 were antibody positive on Stat-Pak for an estimated sensitivity of 87.1%. The study findings indicate that rapid serologic tests used in series are comparable to the SCT and CCT and may have a greater ability to detect TB-infected cervids. PMID:22792512

  13. The occurrence of Bovine viral diarrhea virus in hunter-harvested white-tailed deer (Odocoileus virginianus) in the state of Georgia, southeastern United States.

    PubMed

    Ilha, Marcia R S; Coarsey, Michele; Whittington, Lisa; Rajeev, Sreekumari; Ramamoorthy, Sheela

    2012-11-01

    The prevalence of Bovine viral diarrhea virus (BVDV) in free-ranging white-tailed deer (WTD, Odocoileus virginianus) in the state of Georgia was evaluated using ear notches collected from hunter-harvested deer during the hunting season of 2010-2011. From September to December 2010, 367 ear samples from WTD were collected from 37 counties in Georgia. The samples were from 178 (48.5%) female deer, 187 (51%) male deer, and 2 (0.5%) of unknown sex. The age of the animals varied from 6 months to 6.5 years. The age was not recorded in 34 animals (9.3%). Of the animals with known ages, 42% were under 2 years. Screening of 367 samples for BVDV using an antigen-capture enzyme-linked immunosorbent assay (AgELISA) resulted in 364 negative samples and 3 suspect samples. The 3 suspect samples were negative for BVDV reverse transcription polymerase chain reaction (RT-PCR), virus isolation, and immunohistochemistry. A subpopulation of samples (n = 89) selected from various geographical regions also tested negative for BVDV RT-PCR. In conclusion, although a few of the samples were suspect for the presence of BVDV by AgELISA, the presence of the virus within the deer population studied could not be confirmed further.

  14. WAITING TIME DISTRIBUTION OF SOLAR ENERGETIC PARTICLE EVENTS MODELED WITH A NON-STATIONARY POISSON PROCESS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, C.; Su, W.; Fang, C.

    2014-09-10

    We present a study of the waiting time distributions (WTDs) of solar energetic particle (SEP) events observed with the spacecraft WIND and GOES. The WTDs of both solar electron events (SEEs) and solar proton events (SPEs) display a power-law tail of ∼Δt {sup –γ}. The SEEs display a broken power-law WTD. The power-law index is γ{sub 1} = 0.99 for the short waiting times (<70 hr) and γ{sub 2} = 1.92 for large waiting times (>100 hr). The break of the WTD of SEEs is probably due to the modulation of the corotating interaction regions. The power-law index, γ ∼more » 1.82, is derived for the WTD of the SPEs which is consistent with the WTD of type II radio bursts, indicating a close relationship between the shock wave and the production of energetic protons. The WTDs of SEP events can be modeled with a non-stationary Poisson process, which was proposed to understand the waiting time statistics of solar flares. We generalize the method and find that, if the SEP event rate λ = 1/Δt varies as the time distribution of event rate f(λ) = Aλ{sup –α}exp (– βλ), the time-dependent Poisson distribution can produce a power-law tail WTD of ∼Δt {sup α} {sup –3}, where 0 ≤ α < 2.« less

  15. Evidence of three new members of malignant catarrhal fever virus group in Muskox (Ovibos moschatus), Nubian ibex (Capra nubiana), and gemsbok (Oryx gazella)

    USGS Publications Warehouse

    Li, H.; Gailbreath, K.; Bender, L.C.; West, K.; Keller, J.; Crawford, T.B.

    2003-01-01

    Six members of the malignant catarrhal fever (MCF) virus group of ruminant rhadinoviruses have been identified to date. Four of these viruses are clearly associated with clinical disease: alcelaphine herpesvirus 1 (AlHV-1) carried by wildebeest (Connochaetes spp.); ovine herpesvirus 2 (OvHV-2), ubiquitous in domestic sheep; caprine herpesvirus 2 (CpHV-2), endemic in domestic goats; and the virus of unknown origin found causing classic MCF in white-tailed deer (Odocoileus virginianus; MCFV-WTD). Using serology and polymerase chain reaction with degenerate primers targeting a portion of the herpesviral DNA polymerase gene, evidence of three previously unrecognized rhadinoviruses in the MCF virus group was found in muskox (Ovibos moschatus), Nubian ibex (Capra nubiana), and gemsbok (South African oryx, Oryx gazella), respectively. Based on sequence alignment, the viral sequence in the muskox is most closely related to MCFV-WTD (81.5% sequence identity) and that in the Nubian ibex is closest to CpHV-2 (89.3% identity). The viral sequence in the gemsbok is most closely related to AlHV-1 (85.1% identity). No evidence of disease association with these viruses has been found. ?? Wildlife Disease Association 2003.

  16. Ocular Lesions in Red-Tailed Hawks ( Buteo jamaicensis) With Naturally Acquired West Nile Disease.

    PubMed

    Wünschmann, A; Armién, A G; Khatri, M; Martinez, L C; Willette, M; Glaser, A; Alvarez, J; Redig, P

    2017-03-01

    Ocular lesions are common in red-tailed hawks with West Nile (WN) disease. These lesions consist of pectenitis, choroidal or retinal inflammation, or retinal necrosis, but detailed investigation of the ocular lesions is lacking. Postmortem examination of the eyes of 16 red-tailed hawks with naturally acquired WN disease and 3 red-tailed hawks without WN disease was performed using histopathology, immunohistochemistry for West Nile virus (WNV) antigen, glial fibrillary acid protein, cleaved caspase-3, and the terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling method. Retinal lesions were classified as type I or type II lesions. Type I lesions were characterized by lymphoplasmacytic infiltrates in the subjacent choroid with degeneration limited to the outer retina (type Ia lesion) or with degeneration and necrosis of the outer retina or outer and inner retina (type Ib lesion) while retinal collapse, atrophy, and scarring were hallmarks of type II lesions. Type II retinal lesions were associated with a more pronounced choroiditis. Although not statistically significant, WNV antigen tended to be present in larger quantity in type Ib lesions. Type I lesions are considered acute while type II lesions are chronic. The development of retinal lesions was associated with the presence of an inflammatory infiltrate in the choroid. A breakdown of the blood-retina barrier is suspected to be the main route of infection of the retina. Within the retina, virus appeared to spread via both neuronal and Müller cell processes.

  17. Transmission of Chronic Wasting Disease in Wisconsin White-Tailed Deer: Implications for Disease Spread and Management

    PubMed Central

    Jennelle, Christopher S.; Henaux, Viviane; Wasserberg, Gideon; Thiagarajan, Bala; Rolley, Robert E.; Samuel, Michael D.

    2014-01-01

    Few studies have evaluated the rate of infection or mode of transmission for wildlife diseases, and the implications of alternative management strategies. We used hunter harvest data from 2002 to 2013 to investigate chronic wasting disease (CWD) infection rate and transmission modes, and address how alternative management approaches affect disease dynamics in a Wisconsin white-tailed deer population. Uncertainty regarding demographic impacts of CWD on cervid populations, human and domestic animal health concerns, and potential economic consequences underscore the need for strategies to control CWD distribution and prevalence. Using maximum-likelihood methods to evaluate alternative multi-state deterministic models of CWD transmission, harvest data strongly supports a frequency-dependent transmission structure with sex-specific infection rates that are two times higher in males than females. As transmissible spongiform encephalopathies are an important and difficult-to-study class of diseases with major economic and ecological implications, our work supports the hypothesis of frequency-dependent transmission in wild deer at a broad spatial scale and indicates that effective harvest management can be implemented to control CWD prevalence. Specifically, we show that harvest focused on the greater-affected sex (males) can result in stable population dynamics and control of CWD within the next 50 years, given the constraints of the model. We also provide a quantitative estimate of geographic disease spread in southern Wisconsin, validating qualitative assessments that CWD spreads relatively slowly. Given increased discovery and distribution of CWD throughout North America, insights from our study are valuable to management agencies and to the general public concerned about the impacts of CWD on white-tailed deer populations. PMID:24658535

  18. Transmission of chronic wasting disease in Wisconsin white-tailed deer: Implications for disease spread and management

    USGS Publications Warehouse

    Jennelle, Christopher S.; Henaux, Viviane; Wasserberg, Gideon; Thiagarajan, Bala; Rolley, Robert E.; Samuel, Michael D.

    2014-01-01

    Few studies have evaluated the rate of infection or mode of transmission for wildlife diseases, and the implications of alternative management strategies. We used hunter harvest data from 2002 to 2013 to investigate chronic wasting disease (CWD) infection rate and transmission modes, and address how alternative management approaches affect disease dynamics in a Wisconsin white-tailed deer population. Uncertainty regarding demographic impacts of CWD on cervid populations, human and domestic animal health concerns, and potential economic consequences underscore the need for strategies to control CWD distribution and prevalence. Using maximum-likelihood methods to evaluate alternative multi-state deterministic models of CWD transmission, harvest data strongly supports a frequency-dependent transmission structure with sex-specific infection rates that are two times higher in males than females. As transmissible spongiform encephalopathies are an important and difficult-to-study class of diseases with major economic and ecological implications, our work supports the hypothesis of frequency-dependent transmission in wild deer at a broad spatial scale and indicates that effective harvest management can be implemented to control CWD prevalence. Specifically, we show that harvest focused on the greater-affected sex (males) can result in stable population dynamics and control of CWD within the next 50 years, given the constraints of the model. We also provide a quantitative estimate of geographic disease spread in southern Wisconsin, validating qualitative assessments that CWD spreads relatively slowly. Given increased discovery and distribution of CWD throughout North America, insights from our study are valuable to management agencies and to the general public concerned about the impacts of CWD on white-tailed deer populations.

  19. Parasites, diseases, and health status of sympatric populations of sika deer and white-tailed deer in Maryland and Virginia.

    PubMed

    Davidson, W R; Crow, C B

    1983-10-01

    In July 1981, investigations on parasites, diseases, and herd health status were conducted on sympatric populations of sika deer (Cervus nippon) and white-tailed deer (Odocoileus virginianus) from Blackwater National Wildlife Refuge (Maryland) and Chincoteague National Wildlife Refuge (Virginia) on the Delmarva Peninsula. Five adult deer of each species were collected from each location and subjected to thorough necropsy examinations and laboratory tests. White-tailed deer at both locations harbored protozoan, helminth, and arthropod parasites typically associated with this species throughout the southeastern United States. In contrast, sika deer at both locations harbored only light burdens of ticks, chiggers, and sarcocysts. Serologic tests for antibodies to seven infectious disease agents revealed evidence of exposure to bovine virus diarrhea (BVD) virus, infectious bovine rhinotracheitis virus, and parainfluenza3 virus in white-tailed deer, but only BVD virus in sika deer. At both locations the general health status of sika deer was superior to that of white-tailed deer.

  20. Molecular genealogy tools for white-tailed deer with chronic wasting disease

    PubMed Central

    Ernest, Holly B.; Hoar, Bruce R.; Well, Jay A.; O’Rourke, Katherine I.

    2010-01-01

    Molecular genetic data provide powerful tools for genealogy reconstruction to reveal mechanisms underlying disease ecology. White-tailed deer (Odocoileus virginianus) congregate in matriarchal groups; kin-related close social spacing may be a factor in the spread of infectious diseases. Spread of chronic wasting disease (CWD), a prion disorder of deer and their cervid relatives, is presumed to be associated with direct contact between individuals and by exposure to shared food and water sources contaminated with prions shed by infected deer. Key aspects of disease ecology are yet unknown. DNA tools for pedigree reconstruction were developed to fill knowledge gaps in disease dynamics in prion-infected wild animals. Kinship indices using data from microsatellite loci and sequence haplotypes of mitochondrial DNA were employed to assemble genealogies. Molecular genealogy tools will be useful for landscape-level population genetic research and monitoring, in addition to epidemiologic studies examining transmission of CWD in captive and free-ranging cervids. PMID:20592847

  1. Habitat influences distribution of chronic wasting disease in white-tailed deer

    USGS Publications Warehouse

    Evans, Tyler S.; Kirchgessner, Megan S.; Eyler, B.; Ryan, Christopher W.; Walter, W. David

    2015-01-01

    Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy that was first detected in 1967 in a captive research facility in Colorado. In the northeastern United States, CWD was first confirmed in white-tailed deer (Odocoileus virginianus) in 2005. Because CWD is a new and emerging disease with a spatial distribution that had yet to be assessed in the Northeast, we examined demographic, environmental, and spatial effects to determine how each related to this spatial distribution. The objectives of our study were to identify environmental and spatial effects that best described the spatial distribution of CWD in free-ranging white-tailed deer and identify areas that support deer that are at risk for CWD infection in the Northeast. We used Bayesian hierarchical modeling that incorporated demographic covariates, such as sex and age, along with environmental covariates, which included elevation, slope, riparian corridor, percent clay, and 3 landscapes (i.e., developed, forested, open). The model with the most support contained landscape covariates and spatial effects that represented clustering of CWD in adjacent grid cells. Forested landscapes had the strongest relationship with the distribution of CWD, with increased risk of CWD occurring in areas that had lesser amounts of forest. Our results will assist resource managers in understanding the spatial distribution of CWD within the study area, and in surrounding areas where CWD has yet to be found. Efficiency of disease surveillance and containment efforts can be improved by allocating resources used for surveillance in areas with deer populations that are at greatest risk for infection.

  2. Deer density and disease prevalence influence transmission of Chronic Wasting Disease in White-tailed Deer

    USGS Publications Warehouse

    Samuel, Michael D.; Richards, Bryan J.; Storm, Daniel J.; Rolley, Robert E.; Shelton, Paul; Nicholas S. Keuler,; Timothy R. Van Deelen,

    2013-01-01

    Host-parasite dynamics and strategies for managing infectious diseases of wildlife depend on the functional relationship between disease transmission rates and host density. However, the disease transmission function is rarely known for free-living wildlife, leading to uncertainty regarding the impacts of diseases on host populations and effective control actions. We evaluated the influence of deer density, landscape features, and soil clay content on transmission of chronic wasting disease (CWD) in young (<2-year-old) white-tailed deer (Odocoileus virginianus) in south-central Wisconsin, USA. We evaluated how frequency-dependent, density-dependent, and intermediate transmission models predicted CWD incidence rates in harvested yearling deer. An intermediate transmission model, incorporating both disease prevalence and density of infected deer, performed better than simple density- and frequency-dependent models. Our results indicate a combination of social structure, non-linear relationships between infectious contact and deer density, and distribution of disease among groups are important factors driving CWD infection in young deer. The landscape covariates % deciduous forest cover and forest edge density also were positively associated with infection rates, but soil clay content had no measurable influences on CWD transmission. Lack of strong density-dependent transmission rates indicates that controlling CWD by reducing deer density will be difficult. The consequences of non-linear disease transmission and aggregation of disease on cervid populations deserves further consideration.

  3. Johne's disease in a free-ranging white-tailed deer from Virginia and subsequent surveillance for Mycobacterium avium subspecies paratuberculosis.

    PubMed

    Sleeman, Jonathan M; Manning, Elizabeth J B; Rohm, John H; Sims, Jerry P; Sanchez, Susan; Gerhold, Richard W; Keel, M Kevin

    2009-01-01

    Johne's disease (paratuberculosis) was diagnosed in a 2-yr-old, male, free-ranging white-tailed deer (Odocoileus virginianus) from Fauquier County, Virginia, USA, based on histopathology and culture for Mycobacterium avium subspecies paratuberculosis. Clinical and pathologic findings included emaciation; loss of body fat; chronic diarrhea; severe, chronic, diffuse granulomatous colitis with intrahistiocytic acid-fast bacilli; moderate, chronic granulomatous lymphadenitis with intrahistiocytic acid-fast bacilli; as well as moderate chronic, multifocal, lymphoplasmacytic hepatitis. These findings are consistent with previous reports of Johne's disease in cervids. Subsequent targeted surveillance of 10 emaciated deer with diarrhea, as well as sampling of 72 asymptomatic deer for M. avium subsp. paratuberculosis using culture of multiple tissue types, as well as serology using an enzyme-linked immunosorbent assay (ELISA) optimized for cervid antibody detection, did not reveal any additional cases of infection in this geographic region. To date, this appears to be an isolated case of Johne's disease in a free-ranging white-tailed deer, and infection with the causative agent for Johne's disease appears to be an infrequent occurrence in deer from this region. The origin of infection was most likely domestic ruminants. This is the first report of clinical Johne's disease in a free-ranging white-tailed deer outside of the Florida Keys, USA. Stressors, such as high deer population density and low selenium levels, may have contributed to the development of clinical disease in this case and warrant further investigation.

  4. EAR AND TAIL LESIONS ON CAPTIVE WHITE-TAILED DEER FAWNS (ODOCOILEUS VIRGINIANUS): A CASE STUDY.

    PubMed

    Ferguson, Treena L; Demarais, Stephen; Cooley, Jim; Fleming, Sherrill; Michel, Eric S; Flinn, Emily

    2016-06-01

    During the 2008-2011 time period, undiagnosed lesions were observed in 21 of 150 white-tailed deer fawns (Odocoileus virginianus) that were part of a captive deer herd at Mississippi State University. Clinical findings in healthy and diseased fawns from 0 to 90 days of age included bite and scratch marks followed by moderate to severe ear and tail necrosis. Gross necropsy findings of necrotizing ulcerative dermatitis correlated with histopathologic findings that included focally severe multifocal vasculitis, vascular necrosis, and thrombosis. This article is a clinical description of these previously unreported lesions associated with tissue necrosis in young captive white-tailed deer.

  5. Epizootiology of cranial abscess disease in white-tailed deer (Odocoileus virginianus) of Georgia, USA

    USGS Publications Warehouse

    Cohen, Bradley S.; Belser, Emily H.; Killmaster, Charlie H.; Bowers, John W.; Irwin, Brian J.; Yabsley, Michael J.; Miller, Karl V.

    2015-01-01

    Intracranial abscess disease is a cause of natural mortality for mature male white-tailed deer (Odocoileus virginianus). Most cases of abscesses are associated with bacterial infection byTrueperella (Arcanobacterium) pyogenes, but a complete understanding of the epidemiology of this disease is lacking. We quantified the effects of individual characteristics, site-specific herd demographics, land cover, and soil variables in estimating the probability of this disease. We examined 7,545 white-tailed deer from 60 sites throughout Georgia US for signs of cranial abscesses, the predecessor of intracranial abscesses, and recorded the presence or absence of cranial abscesses for each individual examined. We detected no cranial abscesses in 2,562 female deer but 91 abscesses in 4,983 male deer examined (1.8%). A generalized linear mixed model, treating site as a random effect, was used to examine several potential explanatory risk factors including site-level landscape and soil characteristics (soil and forest type), demographic factors (deer density and male to female ratio), and individual host factors (deer sex and age). Model results indicated that the probability of a male having a cranial abscess increased with age and that adult sex ratio (male:female) was positively associated with this disease. Site-specific variables for land cover and soil types were not strongly associated with observations of the disease at the scale measured and a large amount of among-site variability remained. Given the demonstrated effect of age, gender, and local sex ratios but the remaining unexplained spatial variability, additional investigation into spatiotemporal variation of the presumed bacterial causative agent of cranial abscesses appears warranted.

  6. Spatial epidemiology of chronic wasting disease in Wisconsin white-tailed deer

    USGS Publications Warehouse

    Joly, D.O.; Samuel, M.D.; Langenberg, J.A.; Blanchong, Julie A.; Batha, C.A.; Rolley, R.E.; Keane, D.P.; Ribic, C.A.

    2006-01-01

    Chronic wasting disease (CWD) is a fatal, emerging disease of cervids associated with transmissible protease-resistant prion proteins. The potential for CWD to cause dramatic declines in deer and elk populations and perceived human health risks associated with consuming CWD-contaminated venison have led wildlife agencies to embark on extensive CWD control programs, typically involving culling to reduce deer populations. We characterized the spatial distribution of CWD in white-tailed deer (Odocoileus virginianus) in Wisconsin to facilitate CWD management. We found that CWD prevalence declined with distance from a central location, was locally correlated at a scale of 3.6 km, and was correlated with deer habitat abundance. The latter result is consistent with patterns expected for a positive relationship between density and prevalence of CWD. We recommend management activities focused on culling in geographic areas with high prevalence to have the greatest probability of removing infected individuals. Further research is needed to elucidate the factors in envolved in CWD spread and infection rates, especially the role of density-dependent transmission. ?? Wildlife Disease Association 2006.

  7. Demodectic Mange, Dermatophilosis, and other parasitic and bacterial dermatologic diseases in free-ranging white-tailed deer (Odocoileus virginianus) in the United States from 1975-2012

    USDA-ARS?s Scientific Manuscript database

    The white-tailed deer (Odocoileus virginianus) is a common and widespread North American game species. To evaluate the incidence, clinical manifestations, demography, and pathology of bacterial and parasitic dermatologic diseases in white-tailed deer in the southeastern United States, we retrospecti...

  8. A Tale of Tails: Dissecting the Enhancing Effect of Tailed Primers in Real-Time PCR

    PubMed Central

    Vandenbussche, Frank; Mathijs, Elisabeth; Lefebvre, David; De Clercq, Kris; Van Borm, Steven

    2016-01-01

    Non-specific tail sequences are often added to the 5’-terminus of primers to improve the robustness and overall performance of diagnostic assays. Despite the widespread use of tailed primers, the underlying working mechanism is not well understood. To address this problem, we conducted a detailed in vitro and in silico analysis of the enhancing effect of primer tailing on 2 well-established foot-and-mouth disease virus (FMDV) RT-qPCR assays using an FMDV reference panel. Tailing of the panFMDV-5UTR primers mainly affected the shape of the amplification curves. Modelling of the raw fluorescence data suggested a reduction of the amplification efficiency due to the accumulation of inhibitors. In depth analysis of PCR products indeed revealed the rapid accumulation of forward-primer derived artefacts. More importantly, tailing of the forward primer delayed artefacts formation and concomitantly restored the sigmoidal shape of the amplification curves. Our analysis also showed that primer tailing can alter utilisation patterns of degenerate primers and increase the number of primer variants that are able to participate in the reaction. The impact of tailed primers was less pronounced in the panFMDV-3D assay with only 5 out of 50 isolates showing a clear shift in Cq values. Sequence analysis of the target region of these 5 isolates revealed several mutations in the inter-primer region that extend an existing hairpin structure immediately downstream of the forward primer binding site. Stabilisation of the forward primer with either a tail sequence or cationic spermine units restored the sensitivity of the assay, which suggests that the enhancing effect in the panFMDV-3D assay is due to a more efficient extension of the forward primer. ur results show that primer tailing can alter amplification through various mechanisms that are determined by both the assay and target region. These findings expand our understanding of primer tailing and should enable a more targeted and

  9. Chronic wasting disease in a Wisconsin white-tailed deer farm

    USGS Publications Warehouse

    Keane, D.P.; Barr, D.J.; Bochsler, P.N.; Hall, S.M.; Gidlewski, T.; O'Rourke, K. I.; Spraker, T.R.; Samuel, M.D.

    2008-01-01

    In September 2002, chronic wasting disease (CWD), a prion disorder of captive and wild cervids, was diagnosed in a white-tailed deer (Odocoileus virginianus) from a captive farm in Wisconsin. The facility was subsequently quarantined, and in January 2006 the remaining 76 deer were depopulated. Sixty animals (79%) were found to be positive by immunohistochemical staining for the abnormal prion protein (PrPCWD) in at least one tissue; the prevalence of positive staining was high even in young deer. Although none of the deer displayed clinical signs suggestive of CWD at depopulation, 49 deer had considerable accumulation of the abnormal prion in the medulla at the level of the obex. Extraneural accumulation of the abnormal protein was observed in 59 deer, with accumulation in the retropharyngeal lymph node in 58 of 59 (98%), in the tonsil in 56 of 59 (95%), and in the rectal mucosal lymphoid tissue in 48 of 58 (83%). The retina was positive in 4 deer, all with marked accumulation of prion in the obex. One deer was considered positive for PrPCWD in the brain but not in the extraneural tissue, a novel observation in white-tailed deer. The infection rate in captive deer was 20-fold higher than in wild deer. Although weakly related to infection rates in extraneural tissues, prion genotype was strongly linked to progression of prion accumulation in the obex. Antemortem testing by biopsy of rectoanal mucosal-associated lymphoid tissue (or other peripheral lymphoid tissue) may be a useful adjunct to tonsil biopsy for surveillance in captive herds at risk for CWD infection.

  10. Alternative feeding strategies and potential disease transmission in Wisconsin white-tailed deer

    USGS Publications Warehouse

    Thompson, A.K.; Samuel, M.D.; VanDeelen, T.R.

    2008-01-01

    We conducted experimental feeding using 3 feeding methods (pile, spread, trough) and 2 quantities (rationed, ad libitum) of shelled corn to compare deer activity and behavior with control sites and evaluate potential direct and indirect transmission of infectious disease in white-tailed deer (Odocoileus virginianus) in central Wisconsin, USA. Deer use was higher at 2 of the feeding sites than at natural feeding areas (P ??? 0.02). Deer spent a higher proportion of time (P < 0.01) feeding at pile (49%) and spread (61%) treatments than at natural feeding areas (36%). We found higher deer use for rationed than ad libitum feeding quantities and feeding intensity was greatest at rationed piles and lowest at ad libitum spreads. We also observed closer pairwise distances (???0.3 m) among deer when corn was provided in a trough relative to spread (P=0.03). Supplemental feeding poses risks for both direct and indirect disease transmission due to higher deer concentration and more intensive use relative to control areas. Concentrated feeding and contact among deer at feeding sites can also increase risk for disease transmission. Our results indicated that restrictions on feeding quantity would not mitigate the potential for disease transmission None of the feeding strategies we evaluated substantially reduced the potential risk for disease transmission and banning supplemental feeding to reduce transmission is warranted.

  11. Near-tail reconnection as the cause of cometary tail disconnections

    NASA Technical Reports Server (NTRS)

    Russell, C. T.; Saunders, M. A.; Phillips, J. L.; Fedder, J. A.

    1986-01-01

    In a cometary tail disconnection event the plasma tail appears to separate from the coma and to accelerate away from it. As this occurs a new tail begins to form. It is proposed that these disconnections arise in a manner analogous to geomagnetic substorms, i.e., by the formation of a strongly reconnecting region in the near tail that forms a magnetic island in the coma and ejects the plasma tail by strengthening the magnetic 'slingshot' within the tail. This reconnection process may be triggered by several different processes, such as interplanetary shocks or variations in the Alfven Mach number.

  12. Host culling as an adaptive management tool for chronic wasting disease in white-tailed deer: a modelling study.

    PubMed

    Wasserberg, Gideon; Osnas, Erik E; Rolley, Robert E; Samuel, Michael D

    2009-04-01

    Emerging wildlife diseases pose a significant threat to natural and human systems. Because of real or perceived risks of delayed actions, disease management strategies such as culling are often implemented before thorough scientific knowledge of disease dynamics is available. Adaptive management is a valuable approach in addressing the uncertainty and complexity associated with wildlife disease problems and can be facilitated by using a formal model.We developed a multi-state computer simulation model using age, sex, infection-stage, and seasonality as a tool for scientific learning and managing chronic wasting disease (CWD) in white-tailed deer Odocoileus virginianus. Our matrix model used disease transmission parameters based on data collected through disease management activities. We used this model to evaluate management issues on density- (DD) and frequency-dependent (FD) transmission, time since disease introduction, and deer culling on the demographics, epizootiology, and management of CWD.Both DD and FD models fit the Wisconsin data for a harvested white-tailed deer population, but FD was slightly better. Time since disease introduction was estimated as 36 (95% CI, 24-50) and 188 (41->200) years for DD and FD transmission, respectively. Deer harvest using intermediate to high non-selective rates can be used to reduce uncertainty between DD and FD transmission and improve our prediction of long-term epidemic patterns and host population impacts. A higher harvest rate allows earlier detection of these differences, but substantially reduces deer abundance.Results showed that CWD has spread slowly within Wisconsin deer populations, and therefore, epidemics and disease management are expected to last for decades. Non-hunted deer populations can develop and sustain a high level of infection, generating a substantial risk of disease spread. In contrast, CWD prevalence remains lower in hunted deer populations, but at a higher prevalence the disease competes with

  13. [Assessment of anti-tremorogenic drugs--nicotine-induced tail-tremor model].

    PubMed

    Suemaru, K; Kawasaki, H; Gomita, Y

    1997-06-01

    The repeated administration of nicotine at small doses, which do not produce whole body tremor or convulsion, causes tremor only in the tail (tail-tremor) of rats. The tremor is accompanied by locomotor hyperactivity without rigidity and immobility of the whole body, suggesting that the nicotine-induced tail-tremor model is useful for studying the mechanism underlying tremor associated with movement. The tail-tremor induced by nicotine was suppressed by mecamylamine, a nicotinic antagonist, but not by atropine or scopolamine, muscalinic antagonists. Moreover, the tail-tremor was suppressed by the beta-blockers propranolol and pindolol, as well as the benzodiazepines diazepam and clonazepam. Tremor at rest is observed only in Parkinson's disease, which is improved with anti-muscalinic drugs. Essential tremor is one of the typical tremors connected with movement (postural and kinetic tremor) and is improved with beta-blocker. These findings and results suggest that nicotine-induced tail-tremor is useful for the study of essential tremor in animal models.

  14. Widespread movement of invasive cattle fever ticks (Rhipicephalus microplus) in southern Texas leads to shared local infestations on cattle and deer.

    PubMed

    Busch, Joseph D; Stone, Nathan E; Nottingham, Roxanne; Araya-Anchetta, Ana; Lewis, Jillian; Hochhalter, Christian; Giles, John R; Gruendike, Jeffrey; Freeman, Jeanne; Buckmeier, Greta; Bodine, Deanna; Duhaime, Roberta; Miller, Robert J; Davey, Ronald B; Olafson, Pia U; Scoles, Glen A; Wagner, David M

    2014-04-17

    Rhipicephalus (Boophilus) microplus is a highly-invasive tick that transmits the cattle parasites (Babesia bovis and B. bigemina) that cause cattle fever. R. microplus and Babesia are endemic in Mexico and ticks persist in the United States inside a narrow tick eradication quarantine area (TEQA) along the Rio Grande. This containment area is threatened by unregulated movements of illegal cattle and wildlife like white-tailed deer (WTD; Odocoileus virginianus). Using 11 microsatellite loci we genotyped 1,247 R. microplus from 63 Texas collections, including outbreak infestations from outside the TEQA. We used population genetic analyses to test hypotheses about ecological persistence, tick movement, and impacts of the eradication program in southern Texas. We tested acaricide resistance with larval packet tests (LPTs) on 47 collections. LPTs revealed acaricide resistance in 15/47 collections (32%); 11 were outside the TEQA and three were resistant to multiple acaricides. Some collections highly resistant to permethrin were found on cattle and WTD. Analysis of genetic differentiation over time at seven properties revealed local gene pools with very low levels of differentiation (FST 0.00-0.05), indicating persistence over timespans of up to 29 months. However, in one neighborhood differentiation varied greatly over a 12-month period (FST 0.03-0.13), suggesting recurring immigration from distinct sources as another persistence mechanism. Ticks collected from cattle and WTD at the same location are not differentiated (FST = 0), implicating ticks from WTD as a source of ticks on cattle (and vice versa) and emphasizing the importance of WTD to tick control strategies. We identified four major genetic groups (K = 4) using Bayesian population assignment, suggesting multiple introductions to Texas. Two dispersal mechanisms give rise to new tick infestations: 1) frequent short-distance dispersal from the TEQA; and 2) rare long-distance, human-mediated dispersal from

  15. Widespread movement of invasive cattle fever ticks (Rhipicephalus microplus) in southern Texas leads to shared local infestations on cattle and deer

    PubMed Central

    2014-01-01

    Background Rhipicephalus (Boophilus) microplus is a highly-invasive tick that transmits the cattle parasites (Babesia bovis and B. bigemina) that cause cattle fever. R. microplus and Babesia are endemic in Mexico and ticks persist in the United States inside a narrow tick eradication quarantine area (TEQA) along the Rio Grande. This containment area is threatened by unregulated movements of illegal cattle and wildlife like white-tailed deer (WTD; Odocoileus virginianus). Methods Using 11 microsatellite loci we genotyped 1,247 R. microplus from 63 Texas collections, including outbreak infestations from outside the TEQA. We used population genetic analyses to test hypotheses about ecological persistence, tick movement, and impacts of the eradication program in southern Texas. We tested acaricide resistance with larval packet tests (LPTs) on 47 collections. Results LPTs revealed acaricide resistance in 15/47 collections (32%); 11 were outside the TEQA and three were resistant to multiple acaricides. Some collections highly resistant to permethrin were found on cattle and WTD. Analysis of genetic differentiation over time at seven properties revealed local gene pools with very low levels of differentiation (FST 0.00-0.05), indicating persistence over timespans of up to 29 months. However, in one neighborhood differentiation varied greatly over a 12-month period (FST 0.03-0.13), suggesting recurring immigration from distinct sources as another persistence mechanism. Ticks collected from cattle and WTD at the same location are not differentiated (FST = 0), implicating ticks from WTD as a source of ticks on cattle (and vice versa) and emphasizing the importance of WTD to tick control strategies. We identified four major genetic groups (K = 4) using Bayesian population assignment, suggesting multiple introductions to Texas. Conclusions Two dispersal mechanisms give rise to new tick infestations: 1) frequent short-distance dispersal from the TEQA; and 2) rare long

  16. Tail gut cyst.

    PubMed

    Rao, G Mallikarjuna; Haricharan, P; Ramanujacharyulu, S; Reddy, K Lakshmi

    2002-01-01

    The tail gut is a blind extension of the hindgut into the tail fold just distal to the cloacal membrane. Remnants of this structure may form tail gut cyst. We report a 14-year-old girl with tail gut cyst that presented as acute abdomen. The patient recovered after cyst excision.

  17. Telling tails: selective pressures acting on investment in lizard tails.

    PubMed

    Fleming, Patricia A; Valentine, Leonie E; Bateman, Philip W

    2013-01-01

    Caudal autotomy is a common defense mechanism in lizards, where the animal may lose part or all of its tail to escape entrapment. Lizards show an immense variety in the degree of investment in a tail (i.e., length) across species, with tails of some species up to three or four times body length (snout-vent length [SVL]). Additionally, body size and form also vary dramatically, including variation in leg development and robustness and length of the body and tail. Autotomy is therefore likely to have fundamentally different effects on the overall body form and function in different species, which may be reflected directly in the incidence of lost/regenerating tails within populations or, over a longer period, in terms of relative tail length for different species. We recorded data (literature, museum specimens, field data) for relative tail length (n=350 species) and the incidence of lost/regenerating tails (n=246 species). We compared these (taking phylogeny into account) with intrinsic factors that have been proposed to influence selective pressures acting on caudal autotomy, including body form (robustness, body length, leg development, and tail specialization) and ecology (foraging behavior, physical and temporal niches), in an attempt to identify patterns that might reflect adaptive responses to these different factors. More gracile species have relatively longer tails (all 350 spp., P < 0.001; also significant for five of the six families tested separately), as do longer (all species, P < 0.001; Iguanidae, P < 0.05; Lacertidae, P < 0.001; Scindidae, P < 0.001), climbing (all species, P < 0.05), and diurnal (all species, P < 0.01; Pygopodidae, P < 0.01) species; geckos without specialized tails (P < 0.05); or active-foraging skinks (P < 0.05). We also found some relationships with the data for caudal autotomy, with more lost/regenerating tails for nocturnal lizards (all 246 spp., P < 0.01; Scindidae, P < 0.05), larger skinks (P < 0.05), climbing geckos (P < 0

  18. Contour variations of the body and tail of the pancreas: evaluation with MDCT.

    PubMed

    Omeri, Ahmad Khalid; Matsumoto, Shunro; Kiyonaga, Maki; Takaji, Ryo; Yamada, Yasunari; Kosen, Kazuhisa; Mori, Hiromu; Miyake, Hidetoshi

    2017-06-01

    To analyze morphology/contour variations of the pancreatic body and tail in subjects free of pancreatic disease. We retrospectively reviewed triple-phase, contrast-enhanced multi-detector row computed tomography (3P-CE-MDCT) examinations of 449 patients who had no clinical or CT evidence of pancreatic diseases. These patients were evaluated for morphologic/contour variations of the pancreatic body and tail, which were classified into two types. In Type I, a portion of normal pancreatic parenchyma protrudes >1 cm in maximum diameter from the body or tail (Ia-anteriorly; Ib-posteriorly). Type II was defined as a morphologic anomaly of the pancreatic tail (IIa-globular; IIb-lobulated; IIc-tapered; IId-bifid). Thirty-eight (8.5%) out of 449 patients had body or tail variations. Of those, 23 patients showed Type I variant: Ia in 21 and Ib in two. Type II variant was identified in 15 patients: IIa in eight, IIb in two, IIc in two and IId in three. Protrusion of the anterior surface of the normal pancreas, especially in the tail, was the most frequently occurring variant. Recognizing the types and subtypes of morphology/contour variations of the pancreatic body and tail could help prevent misinterpretation of normal variants as pancreatic tumors on unenhanced MDCT.

  19. Study on the Association between Tail Lesion Score, Cold Carcass Weight, and Viscera Condemnations in Slaughter Pigs

    PubMed Central

    Teixeira, Dayane Lemos; Harley, Sarah; Hanlon, Alison; O’Connell, Niamh Elizabeth; More, Simon John; Manzanilla, Edgar Garcia; Boyle, Laura Ann

    2016-01-01

    The aim of this study was to assess the relationship between tail lesions, cold carcass weight, and viscera condemnations in an Irish abattoir. The following data were collected at the evisceration point from every third pig slaughtered over 7 days: farm identification, sex, tail lesion score, viscera inspection outcome, and cold carcass weight. Tail lesions were scored according to a 5-point scale. Disease lesions responsible for lung (pleurisy, pneumonia, and abscess), heart (pericarditis), and liver (ascariasis) condemnation were recorded based on the decision of the veterinary inspector (VI). Data on 3,143 pigs from 61 batches were available. The relationship between disease lesions, tail lesion score, and cold carcass weight was studied at individual carcass level, while the relationship between disease lesions and tail lesion score was studied at both carcass and batch level. Tail lesions (score ≥1) were found in 72% of the study population, with 2.3% affected by severe tail lesions (scores ≥3). Pleurisy (13.7%) followed by pneumonia (10.4%) showed the highest prevalence, whereas the prevalence of ascariasis showed the greatest variation between batches (0–75%). Tail lesion score, pleurisy, pleuropneumonia, and pericarditis were associated with reductions in carcass cold weight (P ≤ 0.05) ranging from 3 to 6.6 kg. Tail lesion score was associated with condemnations for pleurisy, pneumonia, and pleuropneumonia (P ≤ 0.05) at a batch level. VI shift was associated with condemnations for pneumonia, pleuropneumonia, and pericarditis (P ≤ 0.05) at a carcass level and with pneumonia at a batch level. Sex was not associated with viscera condemnations but males were more likely to be affected by tail lesions. The relationship between overall tail lesion score and the lung diseases at batch level supports the relationship between poor health and poor welfare of pigs on farms. The inclusion of tail lesion scores at post-mortem meat inspection

  20. Akt-mediated cardioprotective effects of aldosterone in type 2 diabetic mice.

    PubMed

    Fazal, Loubina; Azibani, Feriel; Bihry, Nicolas; Coutance, Guillaume; Polidano, Evelyne; Merval, Régine; Vodovar, Nicolas; Launay, Jean-Marie; Delcayre, Claude; Samuel, Jane-Lise

    2014-06-01

    Studies have shown that aldosterone would have angiogenic effects and therefore would be beneficial in the context of cardiovascular diseases. We thus investigated the potential involvement of aldosterone in triggering a cardiac angiogenic response in the context of type-2 diabetes and the molecular pathways involved. Male 3-wk-old aldosterone synthase (AS)-overexpressing mice and their control wild-type (WT) littermates were fed a standard or high-fat, high-sucrose (HFHS) diet. After 6 mo of diet treatment, mice were euthanized, and cardiac samples were assayed by RT-PCR, immunoblotting, and immunohistology. HFHS diet induced type-2 diabetes in WT (WT-D) and AS (AS-D) mice. VEGFa mRNAs decreased in WT-D (-43%, P<0.05 vs. WT) and increased in AS-D mice (+236%, P< 0.01 vs. WT-D). In WT-D mouse hearts, the proapoptotic p38MAPK was activated (P<0.05 vs. WT and AS-D), whereas Akt activity decreased (-64%, P<0.05 vs. WT). The AS mice, which exhibited a cardiac up-regulation of IGF1-R, showed an increase in Akt phosphorylation when diabetes was induced (P<0.05 vs. WT and AS-D). Contrary to WT-D mice, AS-D mouse hearts did not express inflammatory markers and exhibited a normal capillary density (P<0.05 vs. WT-D). To our knowledge, this is the first study providing new insights into the mechanisms whereby aldosterone prevents diabetes-induced cardiac disorders. © FASEB.

  1. Diversity and distribution of white-tailed deer mtdna lineages in chronic wasting disease (cwd) outbreak areas in southern wisconsin, USA

    USGS Publications Warehouse

    Rogers, K.G.; Robinson, S.J.; Samuel, M.D.; Grear, D.A.

    2011-01-01

    Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy affecting North American cervids. Because it is uniformly fatal, the disease is a major concern in the management of white-tailed deer populations. Management programs to control CWD require improved knowledge of deer interaction, movement, and population connectivity that could influence disease transmission and spread. Genetic methods were employed to evaluate connectivity among populations in the CWD management zone of southern Wisconsin. A 576-base-pair region of the mitochondrial DNA of 359 white-tailed deer from 12 sample populations was analyzed. Fifty-eight variable sites were detected within the sequence, defining 43 haplotypes. While most sample populations displayed similar levels of haplotype diversity, individual haplotypes were clustered on the landscape. Spatial clusters of different haplotypes were apparent in distinct ecoregions surrounding CWD outbreak areas. The spatial distribution of mtDNA haplotypes suggests that clustering of the deer matrilineal groups and population connectivity are associated with broad-scale geographic landscape features. These landscape characteristics may also influence the contact rates between groups and therefore the potential spread of CWD; this may be especially true of local disease spread between female social groups. Our results suggest that optimal CWD management needs to be tailored to fit gender-specific dispersal behaviors and regional differences in deer population connectivity. This information will help wildlife managers design surveillance and monitoring efforts based on population interactions and potential deer movement among CWD-affected and unaffected areas. Copyright ?? Taylor & Francis Group, LLC.

  2. REAR PROFILE OF TAIL FROM SECOND LEVEL OF TAIL DOCK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    REAR PROFILE OF TAIL FROM SECOND LEVEL OF TAIL DOCK STAND, SHOWING AIRCRAFT NUMBER (319), HORIZONTAL STABILIZER, TAIL CONE AND COOLING CTS FOR THE AUXILIARY POWER UNIT (APU), MECHANIC PAUL RIDEOUT IS LOWERING THE BALANCE PANELS ON THE STABILIZERS FOR LUBRICATION AND INSPECTION. - Greater Buffalo International Airport, Maintenance Hangar, Buffalo, Erie County, NY

  3. Evaluating spatial overlap and relatedness of white-tailed deer in a chronic wasting disease management zone

    USGS Publications Warehouse

    Samuel, Michael D.; Magle, Seth B.; Van Deelen, Timothy R.; Robinson, Stacie J.; Mathews, Nancy E.

    2013-01-01

    Wildlife disease transmission, at a local scale, can occur from interactions between infected and susceptible conspecifics or from a contaminated environment. Thus, the degree of spatial overlap and rate of contact among deer is likely to impact both direct and indirect transmission of infectious diseases such chronic wasting disease (CWD) or bovine tuberculosis. We identified a strong relationship between degree of spatial overlap (volume of intersection) and genetic relatedness for female white-tailed deer in Wisconsin’s area of highest CWD prevalence. We used volume of intersection as a surrogate for contact rates between deer and concluded that related deer are more likely to have contact, which may drive disease transmission dynamics. In addition, we found that age of deer influences overlap, with fawns exhibiting the highest degree of overlap with other deer. Our results further support the finding that female social groups have higher contact among related deer which can result in transmission of infectious diseases. We suggest that control of large social groups comprised of closely related deer may be an effective strategy in slowing the transmission of infectious pathogens, and CWD in particular.

  4. Influence of ecological factors on prevalence of meningeal worm (Parelaphostrongylus tenuis infection in South Dakota, USA

    USGS Publications Warehouse

    Jacques, Christopher N.; Jenks, Jonathan A.; Grovenburg, Troy W.; Klaver, Robert W.; Dubay, Shelli A.

    2015-01-01

    The meningeal worm (Parelaphostrongylus tenuis) is a nematode parasite that commonly infects white-tailed deer (Odocoileus virginianus; WTD) throughout the deciduous forest biome and deciduous-coniferous ecotone of eastern and central North America; the species is not known to occur west of the grassland biome of central North America. We used county-specific prevalence data to evaluate potential effects of landscape and climatologic factors on the spatial distribution of meningeal worm infection in South Dakota, US. Probability of infection increased 4-fold between eastern and western South Dakota and 1.3-fold for each 1-cm increase in summer precipitation. Sixty-three percent of WTD had only a single worm in the cranium. Expansion of meningeal worm infection across western South Dakota may be inherently low due to the combined effects of arid climate and potential attributes of the Missouri River that limit regional movements by infected WTD. Use of landscape genetic analyses to identify potential relationships between landscape features and population genetic structure of infected deer and parasites may contribute to a greater understanding of regional heterogeneity in meningeal worm infection rates across South Dakota, particularly in counties adjacent to the Missouri River. Future research evaluating heterogeneity in prevalence and intensity of infection between fawn and yearling deer, and the potential role of yearling male deer as dispersal agents of meningeal worms across the Missouri River, also is warranted.

  5. Casein Kinase 2 Reverses Tail-Independent Inactivation of Kinesin-1

    NASA Astrophysics Data System (ADS)

    Xu, Jing

    2013-03-01

    Kinesin-1 is a plus-end microtubule-based motor, and defects in kinesin-based transport are linked to diseases including neurodegeneration. Kinesin can auto-inhibit via a head-tail interaction, but is believed to be active otherwise. Here we report a tail-independent inactivation of kinesin, reversible by the disease-relevant signalling protein, casein kinase 2 (CK2). The majority of initially active kinesin (native or tail-less) loses its ability to interact with microtubules in vitro, and CK2 reverses this inactivation (approximately fourfold) without altering kinesin's single motor properties. This activation pathway does not require motor phosphorylation, and is independent of head-tail auto-inhibition. In cultured mammalian cells, reducing CK2 expression, but not its kinase activity, decreases the force required to stall lipid droplet transport, consistent with a decreased number of active kinesin motors. Our results (Nat. Commun., 3:754, 2012) provide the first direct evidence of a protein kinase upregulating kinesin-based transport, and suggest a novel pathway for regulating the activity of cargo-bound kinesin. Work supported by NIGMS grants GM64624 to SPG, GM74830-06A1 to LH, GM76516 to LB, NS048501 to SJK, and AHA grant 825278F to JX.

  6. Tail-flick test response in 3×Tg-AD mice at early and advanced stages of disease.

    PubMed

    Baeta-Corral, Raquel; Defrin, Ruti; Pick, Chagi G; Giménez-Llort, Lydia

    2015-07-23

    Despite the impact of pain in cognitive dysfunctions and affective disorders has been largely studied, the research that examines pain dimensions in cognitive impairment or dementia is still scarce. In patients with Alzheimer's disease (AD) and related dementias, management of pain is challenging. While the sensory-discriminative dimension of pain is preserved, the cognitive-evaluative and the affective-motivational pain dimensions are affected. Due to the complexity of the disease and the poor self-reports, pain is underdiagnosed and undertreated. In confluence with an impaired thermoregulatory behavior, the patients' ability to confront environmental stressors such as cold temperature can put them at risk of fatal accidental hypothermia. Here, 3xTg-AD mice demonstrate that the sensorial-discriminative threshold to a noxious cold stimulus, as measured by the latency of tail-flicking, was preserved at early and advances stages of disease (7 and 11 month-old, respectively) as compared to age-matched (adulthood and middle aged, respectively) non-transgenic mice (NTg). In both genotypes, the sensory deterioration and poor thermoregulatory behavior associated to age was observed as an increase of tail-flick response and poor sensorimotor performance. At both stages studied, 3xTg-AD mice exhibited BPSD (Behavioral and Psychological Symptoms of Dementia)-like alterations in the corner, open-field, dark-light box and the T-maze tests. In the adult NTg mice, this nociceptive withdrawal response was correlated with copying with stress-related behaviors. This integrative behavioral profile was lost in both groups of 3xTg-AD mice and middle aged controls, suggesting derangements in their subjacent networks and the complex interplay between the pain dimensions in the elderly with dementia. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  7. The importance of localized culling in stabilizing chronic wasting disease prevalence in white-tailed deer populations.

    PubMed

    Manjerovic, Mary Beth; Green, Michelle L; Mateus-Pinilla, Nohra; Novakofski, Jan

    2014-01-01

    Strategies to contain the spread of disease often are developed with incomplete knowledge of the possible outcomes but are intended to minimize the risks associated with delaying control. Culling of game species by government agencies is one approach to control disease in wild populations but is unpopular with hunters and wildlife enthusiasts, politically unpalatable, and erodes public support for agencies responsible for wildlife management. We addressed the functional differences between hunting and government culling programs for managing chronic wasting disease (CWD) in white-tailed deer by comparing prevalence over a 10-year period in Illinois and Wisconsin. When both Illinois and Wisconsin were actively culling from 2003 - 2007, there were no statistical differences between state CWD prevalence estimates. Wisconsin government culling concluded in 2007 and average prevalence over the next five years was 3.09 ± 1.13% with an average annual increase of 0.63%. During that same time period, Illinois continued government culling and there was no change in prevalence throughout Illinois. Despite its unpopularity among hunters, localized culling is a disease management strategy that can maintain low disease prevalence while minimizing impacts on recreational deer harvest. Copyright © 2013 The Authors. Published by Elsevier B.V. All rights reserved.

  8. Effects of chronic wasting disease on reproduction and fawn harvest vulnerability in Wisconsin white-tailed deer

    USGS Publications Warehouse

    Blanchong, Julie A.; Grear, Daniel A.; Weckworth, Byron V.; Keane, Delwyn P.; Scribner, Kim T.; Samuel, Michael D.

    2012-01-01

    Chronic wasting disease (CWD) is a fatal, transmissible spongiform encephalopathy that affects free-ranging and captive North American cervids. Although the impacts of CWD on cervid survival have been documented, little is known about the disease impacts on reproduction and recruitment. We used genetic methods and harvest data (2002–04) to reconstruct parentage for a cohort of white-tailed deer (Odocoileus virginianus) fawns born in spring 2002 and evaluate the effects of CWD infection on reproduction and fawn harvest vulnerability. There was no difference between CWD-positive and CWD-negative male deer in the probability of being a parent. However, CWD-positive females were more likely to be parents than CWD-negative females. Because our results are based on harvested animals, we evaluated the hypothesis that higher parentage rates occurred because fawns with CWD-positive mothers were more vulnerable to harvest. Male fawns with CWD-positive mothers were harvested earlier (>1 mo relative to their mother’s date of harvest) and farther away from their mothers than male fawns with CWD-negative mothers. Male fawns with CWD-positive mothers were also harvested much earlier and farther away than female fawns from CWD-positive mothers. Most female fawns (86%) with CWD-positive mothers were harvested from the same section as their mothers, while almost half of male and female fawns with CWD-negative mothers were farther away. We conclude that preclinical stages of CWD infection do not prohibit white-tailed deer from successfully reproducing. However, apparently higher harvest vulnerability of male fawns with CWD-positive mothers suggests that CWD infection may make females less capable of providing adequate parental care to ensure the survival and recruitment of their fawns.

  9. Attitudes and Knowledge Concerning Corneal Donation in a Population-Based Sample of Urban Chinese Adults.

    PubMed

    Wang, Xiuqin; Jin, Ling; Wang, Jiawei; Garrett, Elizabeth Haid; Shuman, Jeremy; Yang, Ke; Schottman, Tim; Chen, Tingting; Wang, Jun; Wang, Congyao; Congdon, Nathan

    2016-10-01

    To better understand knowledge and attitudes concerning corneal donation among Chinese adults. Randomly selected residents in predetermined age strata 20 to 60+ years completed home-based questionnaires in each of 12 randomly chosen communities in Guangzhou, southern China. Among 1217 selected persons, 430 (35.3%) completed the questionnaires (mean age 40.4 yrs, 57.9% female). Refusers were older (44.8 yrs, P < 0.001), but sex did not differ (52.2% female, P = 0.07). Among participants, 175 (40.7%) were willing to donate their corneas (WTD). Differences between WTD and not WTD included donation knowledge score (range, 1-12) [WTD (SD) 6.91 ± 2.21, not WTD 5.62 ± 2.43, P < 0.001]; having discussed donation (WTD 26.3%, not WTD 8.63%, P < 0.001); viewing donation as unpopular (WTD 88.0%, not WTD 96.5%, P = 0.001); and feeling donation "damages the body" (WTD 15.4%, not WTD 25.7%, P = 0.013). Associated significantly with WTD in multiple regression models were higher knowledge score [odds ratio (OR) = 1.18, 95% confidence interval (CI), 1.04-1.32, P = 0.008]; not feeling donation "damages the body" (OR = 1.91, 95% CI, 1.07-3.43, P = 0.030); and willingness to discuss donation (OR = 10.6, 95% CI, 3.35-33.9, P < 0.001). WTD did not differ by age (>60 yrs: 22/51, 43.1%; ≤60 yrs: 153/379, 40.4%, P = 0.706). Assuming all those refusing the survey would not donate, 14.4% (175/1217) were WTD for themselves, though only 7.1% (86/1217) would do so on behalf of a family member if they did not know the deceased's preference. Interventions to increase knowledge and promote discussions about donation, and policies allowing widespread expression of donation preference, are needed in this setting.

  10. Bacteriological colonisation of uterine cavity: role of tailed intrauterine contraceptive device.

    PubMed Central

    Sparks, R A; Purrier, B G; Watt, P J; Elstein, M

    1981-01-01

    Intrauterine contraceptive devices (IUCDs) are thought to cause pelvic inflammatory disease by allowing vaginal bacteria to pass into the uterus along the tail of the device. In this study the uterine cavities of 22 women using an IUCD were examined by a multiple biopsy technique. All five uteruses with a tailless IUCD were sterile but 15 out of 17 with a tailed device contained bacteria. The bacteria had not reached the fundus and most were commensals. The bacteria were not introduced by insertion of the IUCD as bacteria were present in several cases long after insertion. No differences in bacterial count were found between monofilamentous and multifilamentous devices. Bacteria were cultured from only four devices, which suggested that the bacteria adhere to the endometrium and not to the device. The bacteria in the cavity represent interference by the tail with the protective mechanisms of the uterus, which explains the increase in pelvic inflammatory disease in IUCD users. PMID:6788128

  11. Chronic wasting disease in white-tailed deer: Infection, mortality, and implications for heterogeneous transmission

    USGS Publications Warehouse

    Samuel, Michael D.; Storm, Daniel J.

    2016-01-01

    Chronic wasting disease (CWD) is a fatal neurodegenerative disease affecting free-ranging and captive cervids that now occurs in 24 U.S. states and two Canadian provinces. Despite the potential threat of CWD to deer populations, little is known about the rates of infection and mortality caused by this disease. We used epidemiological models to estimate the force of infection and disease-associated mortality for white-tailed deer in the Wisconsin and Illinois CWD outbreaks. Models were based on age-prevalence data corrected for bias in aging deer using the tooth wear and replacement method. Both male and female deer in the Illinois outbreak had higher corrected age-specific prevalence with slightly higher female infection than deer in the Wisconsin outbreak. Corrected ages produced more complex models with different infection and mortality parameters than those based on apparent prevalence. We found that adult male deer have a more than threefold higher risk of CWD infection than female deer. Males also had higher disease mortality than female deer. As a result, CWD prevalence was twofold higher in adult males than females. We also evaluated the potential impacts of alternative contact structures on transmission dynamics in Wisconsin deer. Results suggested that transmission of CWD among male deer during the nonbreeding season may be a potential mechanism for producing higher rates of infection and prevalence characteristically found in males. However, alternatives based on high environmental transmission and transmission from females to males during the breeding season may also play a role.

  12. Serological activity of white-tail deer against several species of Brucella.

    PubMed

    Salinas-Meléndez, J A; Martínez-Muñoz, A; Avalos-Ramírez, R; Cerutti-Pereyra, N; Riojas-Valdés, V M

    1998-01-01

    In Mexico, brucellosis is a widely distributed disease of domesticated ruminants, but its frequency in wild ruminants has not been documented. Since northeast Mexico is the main distribution area of white-tailed deer and has been reported as an area positive for brucellosis in domesticated species, the present study was conducted in order to determine serological activity against several species of the genus Brucella in white-tailed deer. A total of 208 sera of white-tailed deer were collected during the springs of 1994 and 1995 in the north part of the states of Nuevo León and Coahuila. Each serum was analyzed for the detection of antibodies against two smooth (B. abortus and B. melitensis) and one rough (B. ovis) species of the genus Brucella. The serological tests used for the determination of the presence of antibodies against Brucella were card and plate agglutination for B. abortus, plate agglutination and rivanol precipitation for B. melitensis, and agar gel immunodiffusion for B. ovis. Each assay had positive and negative controls. None of the analyzed samples was found to be positive, and only two sera showed partial plate agglutination against B. melitensis at a dilution of 1:25; however, at higher dilutions and to the rivanol precipitation test the same samples were negative. Therefore, the percentage of positive sera was estimated at 0% (0/208). This result makes evident the absence of positive white-tailed deer against Brucella in the sampled area, despite that this disease is considered present in domesticated species. Therefore, white-tailed deer does not have, at the present time, an important role for the dispersion of the disease. The same result has been reported in other countries.

  13. Climate-Agriculture-Modeling and Decision Tool for Disease (CAMDT-Disease) for seasonal climate forecast-based crop disease risk management in agriculture

    NASA Astrophysics Data System (ADS)

    Kim, K. H.; Lee, S.; Han, E.; Ines, A. V. M.

    2017-12-01

    Climate-Agriculture-Modeling and Decision Tool (CAMDT) is a decision support system (DSS) tool that aims to facilitate translations of probabilistic seasonal climate forecasts (SCF) to crop responses such as yield and water stress. Since CAMDT is a software framework connecting different models and algorithms with SCF information, it can be easily customized for different types of agriculture models. In this study, we replaced the DSSAT-CSM-Rice model originally incorporated in CAMDT with a generic epidemiological model, EPIRICE, to generate a seasonal pest outlook. The resulting CAMDT-Disease generates potential risks for selected fungal, viral, and bacterial diseases of rice over the next months by translating SCFs into agriculturally-relevant risk information. The integrated modeling procedure of CAMDT-Disease first disaggregates a given SCF using temporal downscaling methods (predictWTD or FResampler1), runs EPIRICE with the downscaled weather inputs, and finally visualizes the EPIRICE outputs as disease risk compared to that of the previous year and the 30-year-climatological average. In addition, the easy-to-use graphical user interface adopted from CAMDT allows users to simulate "what-if" scenarios of disease risks over different planting dates with given SCFs. Our future work includes the simulation of the effect of crop disease on yields through the disease simulation models with the DSSAT-CSM-Rice model, as disease remains one of the most critical yield-reducing factors in the field.

  14. A Tale of Two Tails: Exploring Stellar Populations in the Tidal Tails of NGC 3256

    NASA Astrophysics Data System (ADS)

    Rodruck, Michael; Charlton, Jane C.; Konstantopoulos, Iraklis

    2016-01-01

    Galaxy interactions can inject material into the intergalactic medium via violent gravitational dynamics, often visualized in tidal tails. The composition of these tails has remained a mystery, as previous studies have focused on detecting tidal features, rather than the composite material itself. We have developed an observing program using deep, multiband imaging to probe the chaotic regions of tidal tails in search for an underlying stellar population. NGC 3256's twin tidal tails serve as a case study for this new technique. Our results show color values of u - g = 1.15 and r - i = 0.08 for the Western tail, and u - g = 1.33 and r - i = 0.22 for the Eastern tail, corresponding to discrepant ages between the tails of approximately 320 Myr and 785 Myr, respectively. With the interaction age of the system measured at 400 Myr, we find the stellar light in Western tail to be dominated by disrupted star clusters formed during and after the interaction, whereas the light from the Eastern tail is dominated by a 10 Gyr population originating from the host galaxies. We fit the Eastern tail color to a Mixed Stellar Population (MSP) model comprised 94% by mass of a 10 Gyr stellar population, and 6% of a 309 Myr population. We find 52% of the bolometric flux originating from this 10 Gyr population. We also detect a blue to red color gradient in each tail, running from galactic center to tail tip. In addition to tidal tail light, we detect 29 star cluster candidates (SCCs) in the Western tail and 19 in the Eastern, with mean ages of 282 Myr and 98 Myr respectively. Interestingly, we find an excess of very blue SCCs in the Eastern tail as compared to the Western tail, marking a recent, small episode of star formation.

  15. Genetic susceptibility to chronic wasting disease in free-ranging white-tailed deer: complement component C1q and Prnp polymorphisms

    USGS Publications Warehouse

    Blanchong, Julie A.; Heisey, Dennis M.; Scribner, Kim T.; Libants, Scot V.; Johnson, Chad; Aiken, Judd M.; Langenberg, Julia A.; Samuel, Michael D.

    2009-01-01

    The genetic basis of susceptibility to chronic wasting disease (CWD) in free-ranging cervids is of great interest. Association studies of disease susceptibility in free-ranging populations, however, face considerable challenges including: the need for large sample sizes when disease is rare, animals of unknown pedigree create a risk of spurious results due to population admixture, and the inability to control disease exposure or dose. We used an innovative matched case–control design and conditional logistic regression to evaluate associations between polymorphisms of complement C1q and prion protein (Prnp) genes and CWD infection in white-tailed deer from the CWD endemic area in south-central Wisconsin. To reduce problems due to admixture or disease-risk confounding, we used neutral genetic (microsatellite) data to identify closely related CWD-positive (n = 68) and CWD-negative (n = 91) female deer to serve as matched cases and controls. Cases and controls were also matched on factors (sex, location, age) previously demonstrated to affect CWD infection risk. For Prnp, deer with at least one Serine (S) at amino acid 96 were significantly less likely to be CWD-positive relative to deer homozygous for Glycine (G). This is the first characterization of genes associated with the complement system in white-tailed deer. No tests for association between any C1q polymorphism and CWD infection were significant at p < 0.05. After controlling for Prnp, we found weak support for an elevated risk of CWD infection in deer with at least one Glycine (G) at amino acid 56 of the C1qC gene. While we documented numerous amino acid polymorphisms in C1q genes none appear to be strongly associated with CWD susceptibility.

  16. Demographic patterns and harvest vulnerability of chronic wasting disease infected white-tailed deer in Wisconsin

    USGS Publications Warehouse

    Grear, D.A.; Samuel, M.D.; Langenberg, J.A.; Keane, D.

    2006-01-01

    Chronic wasting disease (CWD) is a fatal disease of white-tailed deer (Odocoileus virginianus) caused by transmissible protease-resistant prions. Since the discovery of CWD in southern Wisconsin in 2001, more than 20,000 deer have been removed from a >2,500-km2 disease eradication zone surrounding the three initial cases. Nearly all deer removed were tested for CWD infection and sex, age, and harvest location were recorded. Our analysis used data from a 310-km2 core study area where disease prevalence was higher than surrounding areas. We found no difference in harvest rates between CWD infected and noninfected deer. Our results show that the probability of infection increased with age and that adult males were more likely to be infected than adult females. Six fawns tested positive for CWD, five fawns from the core study area, including the youngest (5 months) free-ranging cervid to test positive. The increase in male prevalence with age is nearly twice the increase found in females. We concluded that CWD is not randomly distributed among deer and that differential transmission among sex and age classes is likely driving the observed patterns in disease prevalence. We discuss alternative hypotheses for CWD transmission and spread and, in addition, discuss several possible nonlinear relationships between prevalence and age. Understanding CWD transmission in free-ranging cervid populations will be essential to the development of strategies to manage this disease in areas where CWD is found, as well as for surveillance strategies in areas where CWD threatens to spread.

  17. Diagnostic accuracy of rectal mucosa biopsy testing for chronic wasting disease within white-tailed deer (Odocoileus virginianus) herds in North America:Effects of age,sex,polymorphism at PRNP codon 96,and disease progression

    USDA-ARS?s Scientific Manuscript database

    An effective live animal diagnostic test is needed to assist in the control of chronic wasting disease (CWD), which has spread through captive and wild herds of white-tailed deer (Odocoileus virginianus) in Canada and the United States. In the present study, the diagnostic accuracy of rectal mucosa ...

  18. Unraveling past impacts of climate change and land management on historic peatland development using proxy-based reconstruction, monitoring data and process modeling.

    PubMed

    Heinemeyer, Andreas; Swindles, Graeme T

    2018-05-08

    Peatlands represent globally significant soil carbon stores that have been accumulating for millennia under water-logged conditions. However, deepening water-table depths (WTD) from climate change or human-induced drainage could stimulate decomposition resulting in peatlands turning from carbon sinks to carbon sources. Contemporary WTD ranges of testate amoebae (TA) are commonly used to predict past WTD in peatlands using quantitative transfer function models. Here we present, for the first time, a study comparing TA-based WTD reconstructions to instrumentally monitored WTD and hydrological model predictions using the MILLENNIA peatland model to examine past peatland responses to climate change and land management. Although there was very good agreement between monitored and modeled WTD, TA-reconstructed water table was consistently deeper. Predictions from a larger European TA transfer function data set were wetter, but the overall directional fit to observed WTD was better for a TA transfer function based on data from northern England. We applied a regression-based offset correction to the reconstructed WTD for the validation period (1931-2010). We then predicted WTD using available climate records as MILLENNIA model input and compared the offset-corrected TA reconstruction to MILLENNIA WTD predictions over an extended period (1750-1931) with available climate reconstructions. Although the comparison revealed striking similarities in predicted overall WTD patterns, particularly for a recent drier period (1965-1995), there were clear periods when TA-based WTD predictions underestimated (i.e. drier during 1830-1930) and overestimated (i.e. wetter during 1760-1830) past WTD compared to MILLENNIA model predictions. Importantly, simulated grouse moor management scenarios may explain the drier TA WTD predictions, resulting in considerable model predicted carbon losses and reduced methane emissions, mainly due to drainage. This study demonstrates the value of a site

  19. Host defense responses associated with experimental hemorrhagic disease in white-tailed deer.

    PubMed

    Quist, C F; Howerth, E W; Stallknecht, D E; Brown, J; Pisell, T; Nettles, V F

    1997-07-01

    Our objectives were to examine the immunity conferred by epizootic hemorrhagic disease virus serotype 2 (EHDV-2) infection in white-tailed deer (Odocoileus virginianus) and determine if this immunity was protective during challenge with homologous (EHDV-2) or heterologous (bluetongue virus serotype 10; BTV-10) virus. Trials were conducted in the fall of 1992 and 1993. In the first experiment, naive white-tailed deer were infected intradermally and subcutaneously with EHDV-2 and monitored via physical examinations, complete blood counts, alpha and beta interferon (IFN) assays, viral isolation, and serology. Infected deer had a wide range of clinical signs in response to infection. Eleven of the 16 deer had body temperature elevations > or = 0.5 C between post-infection day (PID) 4 and 8. Infected deer had decreased lymphocyte counts between PID 6 and 10 that returned to normal levels by PID 17. Severely lymphopenic animals had the most severe clinical signs; five of 10 deer with lymphocyte counts less than 1000 cells/microliters succumbed to the infection. Viremia was detected in all 16 EHDV-2 infected animals by PID 4, and peak viremias occurred between PID 4 and PID 10. Three deer remained viremic until PID 56, the study endpoint. Interferon was first detected between PID 2 and 6. Peak alpha and beta IFN levels coincided with peak viremia in 11 deer. Precipitating and neutralizing antibodies were detected in infected deer by PID 10. In the second experiment, convalescent deer were challenged subcutaneously and intradermally with either EHDV-2 or BTV-10 and similarly monitored. Virus was detected in the blood of all four deer challenged with BTV-10, but viremia was not detected in three EHDV-2-challenged deer. Temperature fluctuations, blood cell parameter changes, and IFN and antibody responses seen in BTV-10-challenged deer were similar to those seen in the initial experiment. Deer challenged with EHDV-2 had mildly increased temperatures, but minimal IFN response

  20. Mapping eastern equine encephalitis virus risk for white-tailed deer in Michigan

    PubMed Central

    Downs, Joni A.; Hyzer, Garrett; Marion, Eric; Smith, Zachary J.; Kelen, Patrick Vander; Unnasch, Thomas R.

    2015-01-01

    Eastern equine encephalitis (EEE) is a mosquito-borne viral disease that is often fatal to humans and horses. Some species including white-tailed deer and passerine birds can survive infection with the EEE virus (EEEV) and develop antibodies that can be detected using laboratory techniques. In this way, collected serum samples from free ranging white-tailed deer can be used to monitor the presence of the virus in ecosystems. This study developed and tested a risk index model designed to predict EEEV activity in white-tailed deer in a three-county area of Michigan. The model evaluates EEEV risk on a continuous scale from 0.0 (no measurable risk) to 1.0 (highest possible risk). High risk habitats are identified as those preferred by white-tailed deer that are also located in close proximity to an abundance of wetlands and lowland forests, which support disease vectors and hosts. The model was developed based on relevant literature and was tested with known locations of infected deer that showed neurological symptoms. The risk index model accurately predicted the known locations, with the mean value for those sites equal to the 94th percentile of values in the study area. The risk map produced by the model could be used refine future EEEV monitoring efforts that use serum samples from free-ranging white-tailed deer to monitor viral activity. Alternatively, it could be used focus educational efforts targeted toward deer hunters that may have elevated risks of infection. PMID:26494931

  1. Wind-tunnel Investigation of End-plate Effects of Horizontal Tails on a Vertical Tail Compared with Available Theory

    NASA Technical Reports Server (NTRS)

    Murray, Harry E

    1946-01-01

    A vertical-tail model with stub fuselage was tested in combination with various simulated horizontal tails to determine the effect of horizontal-tail span and location on the aerodynamic characteristics of the vertical tail. Available theoretical data on end-plate effects were collected and presented in the form most suitable for design purposes. Reasonable agreement was obtained between the measured and theoretical end-plate effects of horizontal tails on vertical tails, and the data indicated that the end-plate effect was determined more by the location of the horizontal tail than by the span of the horizontal tail. The horizontal tail gave most end-plate effect when located near either tip of the vertical tail and, when located near the base of the vertical tail, the end-plate effect was increased by moving the horizontal tail rearward.

  2. The Tail Suspension Test

    PubMed Central

    Terrillion, Chantelle E.; Piantadosi, Sean C.; Bhat, Shambhu; Gould, Todd D.

    2012-01-01

    The tail-suspension test is a mouse behavioral test useful in the screening of potential antidepressant drugs, and assessing of other manipulations that are expected to affect depression related behaviors. Mice are suspended by their tails with tape, in such a position that it cannot escape or hold on to nearby surfaces. During this test, typically six minutes in duration, the resulting escape oriented behaviors are quantified. The tail-suspension test is a valuable tool in drug discovery for high-throughput screening of prospective antidepressant compounds. Here, we describe the details required for implementation of this test with additional emphasis on potential problems that may occur and how to avoid them. We also offer a solution to the tail climbing behavior, a common problem that renders this test useless in some mouse strains, such as the widely used C57BL/6. Specifically, we prevent tail climbing behaviors by passing mouse tails through a small plastic cylinder prior to suspension. Finally, we detail how to manually score the behaviors that are manifested in this test. PMID:22315011

  3. Tail loss compromises immunity in the many-lined skink, Eutropis multifasciata

    NASA Astrophysics Data System (ADS)

    Kuo, Chi-Chien; Yao, Chiou-Ju; Lin, Te-En; Liu, Hsu-Che; Hsu, Yu-Cheng; Hsieh, Ming-Kun; Huang, Wen-San

    2013-04-01

    Tail autotomy incurs energetic costs, and thus, a trade-off in resource allocation may lead to compromised immunity in lizards. We tested the hypothesis that tailless lizards will favor constitutive innate immunity responses over an energetically costly inflammatory response. The influence of fasting and colorful ornamentation was also investigated. We experimentally induced tail autotomy in the lizard Eutropis multifasciata and found that inflammation was suppressed by tail loss, but not further affected by fasting; the suppressive effect of colorful ornamentation was manifested only in males, but not in females. Constitutive innate immunity was not affected by any of these factors. As expected, only costly inflammation was compromised, and a less expensive constitutive innate immunity might be favored as a competent first-line defense during energetically demanding periods. After considering conventional trade-offs among tail regeneration and reproduction, further extending these studies to incorporate disease risk and how this influences escape responses to predators and future reproduction would make worthwhile studies.

  4. Intra-annual patterns in adult band-tailed pigeon survival estimates

    USGS Publications Warehouse

    Casazza, Michael L.; Coates, Peter S.; Overton, Cory T.; Howe, Kristy H.

    2015-01-01

    Implications: We present the first inter-seasonal analysis of survival probability of the Pacific coast race of band-tailed pigeons and illustrate important temporal patterns that may influence future species management including harvest strategies and disease monitoring.

  5. High-protein diet selectively reduces fat mass and improves glucose tolerance in Western-type diet-induced obese rats

    PubMed Central

    Stengel, Andreas; Goebel-Stengel, Miriam; Wang, Lixin; Hu, Eugenia; Karasawa, Hiroshi; Pisegna, Joseph R.

    2013-01-01

    Obesity is an increasing health problem. Because drug treatments are limited, diets remain popular. High-protein diets (HPD) reduce body weight (BW), although the mechanisms are unclear. We investigated physiological mechanisms altered by switching diet induced obesity (DIO) rats from Western-type diet (WTD) to HPD. Male rats were fed standard (SD) or WTD (45% calories from fat). After developing DIO (50% of rats), they were switched to SD (15% calories from protein) or HPD (52% calories from protein) for up to 4 weeks. Food intake (FI), BW, body composition, glucose tolerance, insulin sensitivity, and intestinal hormone plasma levels were monitored. Rats fed WTD showed an increased FI and had a 25% greater BW gain after 9 wk compared with SD (P < 0.05). Diet-induced obese rats switched from WTD to HPD reduced daily FI by 30% on day 1, which lasted to day 9 (−9%) and decreased BW during the 2-wk period compared with SD/SD (P < 0.05). During these 2 wk, WTD/HPD rats lost 72% more fat mass than WTD/SD (P < 0.05), whereas lean mass was unaltered. WTD/HPD rats had lower blood glucose than WTD/SD at 30 min postglucose gavage (P < 0.05). The increase of pancreatic polypeptide and peptide YY during the 2-h dark-phase feeding was higher in WTD/HPD compared with WTD/SD (P < 0.05). These data indicate that HPD reduces BW in WTD rats, which may be related to decreased FI and the selective reduction of fat mass accompanied by improved glucose tolerance, suggesting relevant benefits of HPD in the treatment of obesity. PMID:23883680

  6. TIDAL TAILS OF MINOR MERGERS. II. COMPARING STAR FORMATION IN THE TIDAL TAILS OF NGC 2782

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Knierman, Karen A.; Scowen, Paul; Veach, Todd

    2013-09-10

    The peculiar spiral NGC 2782 is the result of a minor merger with a mass ratio {approx}4: 1 occurring {approx}200 Myr ago. This merger produced a molecular and H I-rich, optically bright eastern tail and an H I-rich, optically faint western tail. Non-detection of CO in the western tail by Braine et al. suggested that star formation had not yet begun. However, deep UBVR and H{alpha} narrowband images show evidence of recent star formation in the western tail, though it lacks massive star clusters and cluster complexes. Using Herschel PACS spectroscopy, we discover 158 {mu}m [C II] emission at themore » location of the three most luminous H{alpha} sources in the eastern tail, but not at the location of the even brighter H{alpha} source in the western tail. The western tail is found to have a normal star formation efficiency (SFE), but the eastern tail has a low SFE. The lack of CO and [C II] emission suggests that the western tail H II region may have a low carbon abundance and be undergoing its first star formation. The western tail is more efficient at forming stars, but lacks massive clusters. We propose that the low SFE in the eastern tail may be due to its formation as a splash region where gas heating is important even though it has sufficient molecular and neutral gas to make massive star clusters. The western tail, which has lower gas surface density and does not form high-mass star clusters, is a tidally formed region where gravitational compression likely enhances star formation.« less

  7. THE NARROW X-RAY TAIL AND DOUBLE Hα TAILS OF ESO 137-002 IN A3627

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, B.; Lin, X. B.; Kong, X.

    2013-11-10

    We present the analysis of a deep Chandra observation of a ∼2 L{sub *} late-type galaxy, ESO 137-002, in the closest rich cluster A3627. The Chandra data reveal a long (∼>40 kpc) and narrow tail with a nearly constant width (∼3 kpc) to the southeast of the galaxy, and a leading edge ∼1.5 kpc from the galaxy center on the upstream side of the tail. The tail is most likely caused by the nearly edge-on stripping of ESO 137-002's interstellar medium (ISM) by ram pressure, compared to the nearly face-on stripping of ESO 137-001 discussed in our previous work. Spectralmore » analysis of individual regions along the tail shows that the gas throughout it has a rather constant temperature, ∼1 keV, very close to the temperature of the tails of ESO 137-001, if the same atomic database is used. The derived gas abundance is low (∼0.2 solar with the single-kT model), an indication of the multiphase nature of the gas in the tail. The mass of the X-ray tail is only a small fraction (<5%) of the initial ISM mass of the galaxy, suggesting that the stripping is most likely at an early stage. However, with any of the single-kT, double-kT, and multi-kT models we tried, the tail is always 'over-pressured' relative to the surrounding intracluster medium (ICM), which could be due to the uncertainties in the abundance, thermal versus non-thermal X-ray emission, or magnetic support in the ICM. The Hα data from the Southern Observatory for Astrophysical Research show a ∼21 kpc tail spatially coincident with the X-ray tail, as well as a secondary tail (∼12 kpc long) to the east of the main tail diverging at an angle of ∼23° and starting at a distance of ∼7.5 kpc from the nucleus. At the position of the secondary Hα tail, the X-ray emission is also enhanced at the ∼2σ level. We compare the tails of ESO 137-001 and ESO 137-002, and also compare the tails to simulations. Both the similarities and differences of the tails pose challenges to the simulations. Several

  8. A study of tail tip necrosis in young fattening bulls on slatted floors.

    PubMed

    Madsen, E B; Nielsen, K

    1985-01-01

    A questionnaire sent to 78 producers revealed that tail tip necrosis was seen only in units with fattening bulls housed on slatted floors. Out of 43 such units, 20 (46.5 per cent) reported that tail tip necrosis was a herd problem. All 43 herds were visited, owners were interviewed and housing and management data recorded. It is concluded that tail tip necrosis is a multifactorial disease. The initial lesion is caused by tramping, but the following factors are essential in the development and severity of the disease, i) slatted concrete floors, ii) close confinement, iii) hot season and iv) body weight above 200 kg. The stocking density (expressed as kg bodyweight per square meter pen) was significantly higher in problem herds (210 kg/m2) than in control herds (165 kg/m2). There was a close relationship between high environmental temperature and tail tip necroses. The majority of incidents occurred during the warm season (May through September), very few cases were seen during the colder months. The general morbidity and mortality rates were significantly higher in problem herds than in control herds. Microbiology of affected tails revealed mixed infections in most cases, with Corynebacterium pyogenes and Bacteroides melaninogenicus as the most frequently isolated organisms. Principles of treatment and prevention are discussed. There is evidence to assume that a 10-20 per cent reduction in stocking density could be an efficient prophylactic measure.

  9. Automatic early warning of tail biting in pigs: 3D cameras can detect lowered tail posture before an outbreak

    PubMed Central

    Jack, Mhairi; Futro, Agnieszka; Talbot, Darren; Zhu, Qiming; Barclay, David; Baxter, Emma M.

    2018-01-01

    Tail biting is a major welfare and economic problem for indoor pig producers worldwide. Low tail posture is an early warning sign which could reduce tail biting unpredictability. Taking a precision livestock farming approach, we used Time-of-flight 3D cameras, processing data with machine vision algorithms, to automate the measurement of pig tail posture. Validation of the 3D algorithm found an accuracy of 73.9% at detecting low vs. not low tails (Sensitivity 88.4%, Specificity 66.8%). Twenty-three groups of 29 pigs per group were reared with intact (not docked) tails under typical commercial conditions over 8 batches. 15 groups had tail biting outbreaks, following which enrichment was added to pens and biters and/or victims were removed and treated. 3D data from outbreak groups showed the proportion of low tail detections increased pre-outbreak and declined post-outbreak. Pre-outbreak, the increase in low tails occurred at an increasing rate over time, and the proportion of low tails was higher one week pre-outbreak (-1) than 2 weeks pre-outbreak (-2). Within each batch, an outbreak and a non-outbreak control group were identified. Outbreak groups had more 3D low tail detections in weeks -1, +1 and +2 than their matched controls. Comparing 3D tail posture and tail injury scoring data, a greater proportion of low tails was associated with more injured pigs. Low tails might indicate more than just tail biting as tail posture varied between groups and over time and the proportion of low tails increased when pigs were moved to a new pen. Our findings demonstrate the potential for a 3D machine vision system to automate tail posture detection and provide early warning of tail biting on farm. PMID:29617403

  10. Can loss of the swallow tail sign help distinguish between Parkinson Disease and the Parkinson-Plus syndromes?

    PubMed

    Oustwani, Christopher Sami; Korutz, Alexander William; Lester, Malisa Siri; Kianirad, Yasaman; Simuni, Tanya; Hijaz, Tarek Aref

    To determine if loss of the swallow tail sign (STS) can distinguish Parkinson Disease (PD) from the Parkinson-Plus syndromes. Twenty-five patients with PD, 21 with Parkinson-Plus syndromes, and 14 control patients were included. Presence of the STS was assessed. The STS was present in 79% of controls, statistically greater than the PD/Parkinson-Plus patients. There was no difference in the presence of the STS between the PD/Parkinson-Plus subgroups or when scanning at 1.5 T or 3 T. Loss of the STS could not distinguish between PD and Parkinson-Plus patients. The STS can be identified at both 1.5 T and 3 T. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Nesting habitat relationships of sympatric Crested Caracaras, Red-tailed Hawks, and White-tailed Hawks in South Texas

    USGS Publications Warehouse

    Actkinson, M.A.; Kuvlesky, W.P.; Boal, C.W.; Brennan, L.A.; Hernandez, F.

    2007-01-01

    We quantified nesting-site habitats for sympatric White-tailed Hawks (Buteo albicaudatus) (n = 40), Red-tailed Hawks (B. jamaicensis) (n = 39), and Crested Caracaras (Caracara cheriway) (n = 24) in the Coastal Sand Plain of south Texas. White-tailed Hawks and Crested Caracara nest sites occurred in savannas, whereas Red-tailed Hawk nest sites occurred in woodlands on the edge of savannas. White-tailed Hawk nest sites were in shrubs and trees that were shorter (3.5 ?? 1.0 m) and had smaller canopy diameters (5.5 ?? 2.1 m) than those of Red-tailed Hawks (10.1 ?? 2.0 m, 13.7 ?? 5.8 m) and Crested Caracaras (5.6 ?? 1.7 m, 8.5 ?? 3.5 m). Red-tailed Hawk nest sites had higher woody densities (15.7 ?? 9.6 plants) and more woody cover (84 ?? 19%) than those of White-tailed Hawks (5.6 ?? 5.8 plants, 20 ?? 21%) and Crested Caracaras (9.9 ?? 6.7 plants, 55 ?? 34%). Crested Caracara nest sites were in dense, multi-branched shrubs composed of more living material (97 ?? 3%) than those of White-tailed (88 ?? 18%) and Red-tailed hawks (88 ?? 18%). Nest sites of White-tailed Hawks, Red-tailed Hawks, and Crested Caracaras were similar to random samples from the surrounding habitat indicating that preferred nesting habitat was available for each of these species at least within 60 m of active nest sites. Nest tree height, along with woody plant and native grass cover best discriminated nest sites among the three raptor species. There was no overlap at Red-tailed and White-tailed hawk nest sites in vegetation structure, while Crested Caracara nests were in habitat intermediate between the two other species. Partitioning of nesting habitat may be how these raptor species co-exist at the broader landscape scale of our study area in the Coastal Sand Plain of Texas.

  12. Tail Buffeting

    NASA Technical Reports Server (NTRS)

    Abdrashitov, G.

    1943-01-01

    An approximate theory of buffeting is here presented, based on the assumption of harmonic disturbing forces. Two cases of buffeting are considered: namely, for a tail angle of attack greater and less than the stalling angle, respectively. On the basis of the tests conducted and the results of foreign investigators, a general analysis is given of the nature of the forced vibrations the possible load limits on the tail, and the methods of elimination of buffeting.

  13. Research on Long Tail Recommendation Algorithm

    NASA Astrophysics Data System (ADS)

    Hu, Xuezhi; Zhang, Chuang; Wu, Ming; Zeng, Yang

    2017-10-01

    Most recommendation systems in the major electronic commerce platforms are influenced by the long tail effect more or less. There are sufficient researches of how to assess recommendation effect while no criteria to evaluate long tail recommendation rate. In this study, we first discussed the existing problems of recommending long tail products through specific experiments. Then we proposed a long tail evaluation criteria and compared the performance in long tail recommendation between different models.

  14. Runaway tails in magnetized plasmas

    NASA Technical Reports Server (NTRS)

    Moghaddam-Taaheri, E.; Vlahos, L.; Rowland, H. L.; Papadopoulos, K.

    1985-01-01

    The evolution of a runaway tail driven by a dc electric field in a magnetized plasma is analyzed. Depending on the strength of the electric field and the ratio of plasma to gyrofrequency, there are three different regimes in the evolution of the tail. The tail can be (1) stable with electrons accelerated to large parallel velocities, (2) unstable to Cerenkov resonance because of the depletion of the bulk and the formation of a positive slope, (3) unstable to the anomalous Doppler resonance instability driven by the large velocity anisotropy in the tail. Once an instability is triggered (Cerenkov or anomalous Doppler resonance) the tail relaxes into an isotropic distribution. The role of a convection type loss term is also discussed.

  15. Laboratory validation of two real-time RT-PCR methods with 5'-tailed primers for an enhanced detection of foot-and-mouth disease virus.

    PubMed

    Vandenbussche, Frank; Lefebvre, David J; De Leeuw, Ilse; Van Borm, Steven; De Clercq, Kris

    2017-08-01

    The 3D and 5UTR real-time RT-PCR assays (RT-qPCR) from Callahan et al. (2002) and Reid et al. (2002) are commonly used reference methods for the detection of foot-and-mouth disease virus (FMDV). For an optimal detection of FMDV in clinical samples, it is advised to use both assays simultaneously (King et al., 2006). Recently, Vandenbussche et al. (2016) showed that the addition of 5'-tails to the FMDV-specific primers enhances the detection of FMDV in both the 3D and the 5UTR RT-qPCR assay. To validate the 3D and 5UTR RT-qPCR assays with 5'-tailed primers for diagnostic purposes, both assays were run in parallel in a triplex one-step RT-qPCR protocol with beta-actin as an internal control and synthetic RNA as an external control. We obtained low limits of detection and high linearity's, high repeatability and reproducibility, near 100% analytical specificity and >99% diagnostic accuracy for both assays. It was concluded that the 3D and 5UTR RT-qPCR assays with 5'-tailed primers are particularly suited for the detection of FMDV as well as to exclude the presence of FMDV. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Water table depth fluctuations during ENSO phenomenon on different tropical peat swamp forest land covers in Katingan, Indonesia

    NASA Astrophysics Data System (ADS)

    Rossita, A.; Witono, A.; Darusman, T.; Lestari, D. P.; Risdiyanto, I.

    2018-03-01

    As it is the main role to maintain hydrological function, peatland has been a limelight since drainage construction for agriculture evolved. Drainage construction will decrease water table depth (WTD) and result in CO2 emission release to the atmosphere. Regardless of human intervention, WTD fluctuations can be affected by seasonal climate and climate variability, foremost El Niño Southern Oscillation (ENSO). This study aims to determine the correlation between rainfall in Katingan and ENSO index, analyze the pattern of WTD fluctuation of open area and forest area in 2015 (during very strong El Niño) and 2016 (during weak La Niña), calculate the WTD trendline slope during the dry season, and rainfall and WTD correlation. The result showed that open area has a sharper slope of decreasing or increasing WTD when entering the dry, compared to the forest area. Also, it is found that very strong El Niño in 2015 generated a pattern of more extreme decreasing WTD during the dry season than weak La Niña in 2016.

  17. Experimental Transmission of Chronic Wasting Disease (CWD) from Elk (Cervus elaphus nelsoni) and White-tailed Deer (Odocoileus virginianus) to Fallow Deer (Dama dama) by Intracerebral Route: Final Report

    USDA-ARS?s Scientific Manuscript database

    In this communication we report final observations on experimental transmission of chronic wasting disease (CWD) from elk (Cervus elaphus nelsoni) and white tailed deer (Odocoileus virginianus) to fallow deer (Dama dama). The study was terminated 5 years after it was initiated. Thirteen fawns were i...

  18. White-tailed deer harvest from the chronic wasting disease eradication zone in south-central Wisconsin

    USGS Publications Warehouse

    Blanchong, Julie A.; Joly, D.O.; Samuel, M.D.; Langenberg, J.A.; Rolley, R.E.; Sausen, J.F.

    2006-01-01

    Chronic wasting disease (CWD) was discovered in free-ranging white-tailed deer (Odocoileus virginianus) in south-central Wisconsin in 2002. The current control method for CWD in the state is the harvest of deer from affected areas to reduce population density and lower CWD transmission. We used spatial regression methods to identify factors associated with deer harvest across south-central Wisconsin. Harvest of deer by hunters was positively related to deer density (slope=0.003, 95% CI=0.0001-0.006), the number of landowners that requested harvest permits (slope=0.071, 95% CI=0.037-0.105), and proximity to the area of highest CWD infection (slope=-0.041, 95% CI=-0.056- -0.027). Concomitantly, harvest was not impacted in areas where landowners signed a petition protesting intensive deer reduction (slope=-0.00006, 95% CI=-0.0005-0.0003). Our results suggest that the success of programs designed to reduce deer populations for disease control or to reduce overabundance in Wisconsin are dependent on landowner and hunter participation. We recommend that programs or actions implemented to eradicate or mitigate the spread of CWD should monitor and assess deer population reduction and evaluate factors affecting program success to improve methods to meet management goals.

  19. Physiologic Reference Ranges for Captive Black-Tailed Prairie Dogs (Cynomys ludovicianus)

    PubMed Central

    Keckler, M Shannon; Gallardo-Romero, Nadia F; Langham, Gregory L; Damon, Inger K; Karem, Kevin L; Carroll, Darin S

    2010-01-01

    The black-tailed prairie dog (Cynomys ludovicianus) is a member of the order Rodentia and the family Sciuridae. Ecologically, prairie dogs are a keystone species in prairie ecology. This species is used as an animal model for human gallbladder disease and diseases caused by infection with Clostridium difficile, Yersinia pestis, Francisella tularensis, and most recently, Orthopoxvirus. Despite increasing numbers of prairie dogs used in research and kept as pets, few data are available on their baseline physiology in animal facility housing conditions. To establish baseline physiologic reference ranges, we designed a study using 18 wild-caught black-tailed prairie dogs. Telemetry data were analyzed to establish circadian rhythms for activity and temperature. In addition, hematologic and serum chemistry analyses were performed. Baseline measurements were used to establish the mean for each animal, which then were compiled and analyzed to determine the reference ranges. Here we present physiologic data on serum chemistry and hematology profiles, as well as weight, core body temperature, and daily activity patterns for black-tailed prairie dogs. These results reflect the use of multiple measurements from species- and age-matched prairie dogs and likely will be useful to ecologists, scientists interested in using this animal model in research, and veterinarians caring for pet prairie dogs. PMID:20587156

  20. The new idea of transporting tailings-logs in tailings slurry pipeline and the innovation of technology of mining waste-fill method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lin Yu; Wang Fuji; Tao Yan

    2000-07-01

    This paper introduced a new idea of transporting mine tailings-logs in mine tailings-slurry pipeline and a new technology of mine cemented filing of tailings-logs with tailings-slurry. The hydraulic principles, the compaction of tailings-logs and the mechanic function of fillbody of tailings-logs cemented by tailings-slurry have been discussed.

  1. White-Tailed Deer Susceptible to Scrapie by Natural Route of Infection

    USDA-ARS?s Scientific Manuscript database

    Interspecies transmission studies afford the opportunity to better understand the potential host range and origins of prion diseases. Previous experiments demonstrated that white-tailed deer are susceptible to sheep-derived scrapie by intracranial inoculation. The purpose of this study was to determ...

  2. White-Tailed Deer Susceptible to Scrapie by Natural Route of Infection

    USDA-ARS?s Scientific Manuscript database

    Interspecies transmission studies afford the opportunity to better understand the potential host range and origins of prion diseases. Previous experiments demonstrated that white-tailed deer are susceptible to sheep-derived scrapie by intracranial inoculation. The purpose of an ongoing study is to...

  3. White-tailed Deer are Susceptible to Sheep Scrapie by Intracerebral Inoculation

    USDA-ARS?s Scientific Manuscript database

    Interspecies transmission studies afford the opportunity to better understand the potential host range and origins of prion diseases. The purpose of this experiment was to determine susceptibility of white-tailed deer to scrapie after intracerebral inoculation and to compare clinical signs and lesi...

  4. Phytoremediation of Alberta oil sand tailings using native plants and fungal endophytes

    NASA Astrophysics Data System (ADS)

    Repas, T.; Germida, J.; Kaminskyj, S.

    2012-04-01

    Fungal endophytes colonize host plants without causing disease. Some endophytes confer plant tolerance to harsh environments. One such endophyte, Trichoderma harzianum strain TSTh20-1, was isolated from a plant growing on Athabasca oil sand tailings. Tailing sands are a high volume waste product from oil sand extraction that the industry is required to remediate. Tailing sands are low in organic carbon and mineral nutrients, and are hydrophobic due to residual polyaromatic hydrocarbons. Typically, tailing sands are remediated by planting young trees in large quantities of mulch plus mineral fertilizer, which is costly and labour intensive. In greenhouse trials, TSTh20-1 supports growth of tomato seedlings on tailing sands without fertilizer. The potential use of TSTh20-1 in combination with native grasses and forbs to remediate under field conditions is being assessed. Twenty-three commercially available plant species are being screened for seed germination and growth on tailing sands in the presence of TSTh20-1. The best candidates from this group will be used in greenhouse and small scale field trials. Potential mechanisms that contribute to endophyte-induced plant growth promotion, such as plant hormone production, stress tolerance, mineral solubilization, and uptake are also being assessed. As well, TSTh20-1 appears to be remarkably frugal in its nutrient requirements and the possibility that this attribute is characteristic of other plant-fungal endophytes from harsh environments is under study.

  5. Intentions in wishes to die: analysis and a typology – A report of 30 qualitative case studies of terminally ill cancer patients in palliative care

    PubMed Central

    Ohnsorge, K; Gudat, H; Rehmann-Sutter, C

    2014-01-01

    Objective To investigate the variations in and intentions of wishes to die (WTD) of palliative care cancer patients. Methods Thirty terminally ill cancer patients, their caregivers and relatives in a hospice, an oncology palliative care ward of a general hospital, and an outpatient palliative care service. 116 semistructured qualitative interviews analyzed by a combined approach using Grounded Theory and Interpretive Phenomenological Analysis. Results A WTD is dynamic and interactive. Its subjective phenomenology can be described by three aspects: intentions, motivations, and interactions. In this article, we present a typology of the possible intentions. We identified nine different (ideal) types of intentions that WTD statements might have, other than wishing to live and accepting death. Many WTD statements do not imply a desire to hasten death. The intentions of statements differ according to whether a WTD is related to as imaginary or as an action. Often WTD statements contain several partial wishes, which can be in tension with each other and form a dynamic, sometimes unstable equilibrium. Conclusions Terminally ill persons' WTD statements differ in their intention, and deeper knowledge about these differences is ethically relevant. PMID:24706488

  6. Exploring Mercury Tail

    NASA Image and Video Library

    2008-08-26

    As the MESSENGER spacecraft approached Mercury, the UVVS field of view was scanned across the planet's exospheric "tail," which is produced by the solar wind pushing Mercury's exosphere (the planet's extremely thin atmosphere) outward. This figure, recently published in Science magazine, shows a map of the distribution of sodium atoms as they stream away from the planet (see PIA10396); red and yellow colors represent a higher abundance of sodium than darker shades of blue and purple, as shown in the colored scale bar, which gives the brightness intensity in units of kiloRayleighs. The escaping atoms eventually form a comet-like tail that extends in the direction opposite that of the Sun for many planetary radii. The small squares outlined in black correspond to individual measurements that were used to create the full map. These measurements are the highest-spatial-resolution observations ever made of Mercury's tail. In less than six weeks, on October 6, 2008, similar measurements will be made during MESSENGER's second flyby of Mercury. Comparing the measurements from the two flybys will provide an unprecedented look at how Mercury's dynamic exosphere and tail vary with time. Date Acquired: January 14, 2008. http://photojournal.jpl.nasa.gov/catalog/PIA11076

  7. Tail-scope: Using friends to estimate heavy tails of degree distributions in large-scale complex networks

    NASA Astrophysics Data System (ADS)

    Eom, Young-Ho; Jo, Hang-Hyun

    2015-05-01

    Many complex networks in natural and social phenomena have often been characterized by heavy-tailed degree distributions. However, due to rapidly growing size of network data and concerns on privacy issues about using these data, it becomes more difficult to analyze complete data sets. Thus, it is crucial to devise effective and efficient estimation methods for heavy tails of degree distributions in large-scale networks only using local information of a small fraction of sampled nodes. Here we propose a tail-scope method based on local observational bias of the friendship paradox. We show that the tail-scope method outperforms the uniform node sampling for estimating heavy tails of degree distributions, while the opposite tendency is observed in the range of small degrees. In order to take advantages of both sampling methods, we devise the hybrid method that successfully recovers the whole range of degree distributions. Our tail-scope method shows how structural heterogeneities of large-scale complex networks can be used to effectively reveal the network structure only with limited local information.

  8. Does climate have heavy tails?

    NASA Astrophysics Data System (ADS)

    Bermejo, Miguel; Mudelsee, Manfred

    2013-04-01

    When we speak about a distribution with heavy tails, we are referring to the probability of the existence of extreme values will be relatively large. Several heavy-tail models are constructed from Poisson processes, which are the most tractable models. Among such processes, one of the most important are the Lévy processes, which are those process with independent, stationary increments and stochastic continuity. If the random component of a climate process that generates the data exhibits a heavy-tail distribution, and if that fact is ignored by assuming a finite-variance distribution, then there would be serious consequences (in the form, e.g., of bias) for the analysis of extreme values. Yet, it appears that it is an open question to what extent and degree climate data exhibit heavy-tail phenomena. We present a study about the statistical inference in the presence of heavy-tail distribution. In particular, we explore (1) the estimation of tail index of the marginal distribution using several estimation techniques (e.g., Hill estimator, Pickands estimator) and (2) the power of hypothesis tests. The performance of the different methods are compared using artificial time-series by means of Monte Carlo experiments. We systematically apply the heavy tail inference to observed climate data, in particular we focus on time series data. We study several proxy and directly observed climate variables from the instrumental period, the Holocene and the Pleistocene. This work receives financial support from the European Commission (Marie Curie Initial Training Network LINC, No. 289447, within the 7th Framework Programme).

  9. The Tail of BPM

    NASA Astrophysics Data System (ADS)

    Kruba, Steve; Meyer, Jim

    Business process management suites (BPMS's) represent one of the fastest growing segments in the software industry as organizations automate their key business processes. As this market matures, it is interesting to compare it to Chris Anderson's 'Long Tail.' Although the 2004 "Long Tail" article in Wired magazine was primarily about the media and entertainment industries, it has since been applied (and perhaps misapplied) to other markets. Analysts describe a "Tail of BPM" market that is, perhaps, several times larger than the traditional BPMS product market. This paper will draw comparisons between the concepts in Anderson's article (and subsequent book) and the BPM solutions market.

  10. Active tails enhance arboreal acrobatics in geckos

    PubMed Central

    Jusufi, Ardian; Goldman, Daniel I.; Revzen, Shai; Full, Robert J.

    2008-01-01

    Geckos are nature's elite climbers. Their remarkable climbing feats have been attributed to specialized feet with hairy toes that uncurl and peel in milliseconds. Here, we report that the secret to the gecko's arboreal acrobatics includes an active tail. We examine the tail's role during rapid climbing, aerial descent, and gliding. We show that a gecko's tail functions as an emergency fifth leg to prevent falling during rapid climbing. A response initiated by slipping causes the tail tip to push against the vertical surface, thereby preventing pitch-back of the head and upper body. When pitch-back cannot be prevented, geckos avoid falling by placing their tail in a posture similar to a bicycle's kickstand. Should a gecko fall with its back to the ground, a swing of its tail induces the most rapid, zero-angular momentum air-righting response yet measured. Once righted to a sprawled gliding posture, circular tail movements control yaw and pitch as the gecko descends. Our results suggest that large, active tails can function as effective control appendages. These results have provided biological inspiration for the design of an active tail on a climbing robot, and we anticipate their use in small, unmanned gliding vehicles and multisegment spacecraft. PMID:18347344

  11. Forest cover influences dispersal distance of white-tailed deer

    USGS Publications Warehouse

    Long, E.S.; Diefenbach, D.R.; Rosenberry, C.S.; Wallingford, B.D.; Grund, M.D.

    2005-01-01

    Animal dispersal patterns influence gene flow, disease spread, population dynamics, spread of invasive species, and establishment of rare or endangered species. Although differences in dispersal distances among taxa have been reported, few studies have described plasticity of dispersal distance among populations of a single species. In 2002-2003, we radiomarked 308 juvenile (7- to 10-month-old), male white-tailed deer (Odocoileus virginianus) in 2 study areas in Pennsylvania. By using a meta-analysis approach, we compared dispersal rates and distances from these populations together with published reports of 10 other nonmigratory populations of white-tailed deer. Population density did not influence dispersal rate or dispersal distance, nor did forest cover influence dispersal rate. However, average (r2 = 0.94, P < 0.001, d.f. = 9) and maximum (r2 = 0.86, P = 0.001, d.f. = 7) dispersal distances of juvenile male deer were greater in habitats with less forest cover. Hence, dispersal behavior of this habitat generalist varies, and use of landscape data to predict population-specific dispersal distances may aid efforts to model population spread, gene flow, or disease transmission. ?? 2005 American Society of Mammalogists.

  12. Surveillance and monitoring of white-tailed deer for chronic wasting disease in the northeastern United States

    USGS Publications Warehouse

    Evans, Tyler S.; Schuler, Krysten L.; Walter, W. David

    2014-01-01

    Chronic wasting disease (CWD) is a prion disease that affects both wild and captive cervid populations. In the past 45 y, CWD has spread from northern Colorado to all bordering states, as well as the midwestern United States (Midwest) and northeastern United States (Northeast), Canada, and South Korea. Because CWD is a relatively new issue for wildlife management agencies in the Northeast, we surveyed a representative (e.g., cervid biologist, wildlife veterinarian) from 14 states to gain a better understanding of state-specific surveillance measures. Between 2002 and 2012, New York (37,093) and Pennsylvania (35,324) tested the greatest number of harvested white-tailed deer Odocoileus virginianus in the Northeast. Additionally, the 14 states surveyed have tested 121,730 harvested deer, or approximately 15,216/y, since CWD was first detected in 2005. The most common tissues used by agencies in the Northeast for testing were retropharyngeal lymph nodes, which have been determined to be the most reliable in detecting CWD in cervids. Understanding CWD surveillance efforts at a regional scale can help to provide guidance for the development of new surveillance plans or the improvement of existing ones. Furthermore, collaborations among state and regional agencies in the Northeast may attempt to identify deficiencies in surveillance by state or subregion.

  13. Comparison of the breeding biology of sympatric red-tailed Hawks, White-tailed Hawks, and Crested Caracaras in south Texas

    USGS Publications Warehouse

    Actkinson, M.A.; Kuvlesky, W.P.; Boal, C.W.; Brennan, L.A.; Hernandez, F.

    2009-01-01

    We compared the breeding biology of sympatric nesting Red-tailed Hawks (Buteo jamaicensis), White-tailed Hawks (Buteo albicaudatus), and Crested Caracaras (Caracara cheriway) in south Texas during 2003 and 2004. We monitored 46 breeding attempts by Red-tailed Hawks, 56 by White-tailed Hawks, and 27 by Crested Caracaras. Observed nesting success was similar for Red-tailed Hawks (62%) and Crested Caracaras (61%), but lower for White-tailed Hawks (51%). Daily survival rates (0.99) were the same for all three species. Red-tailed Hawks and White-tailed Hawks both fledged 1.13 young per nesting pair and Crested Caracaras fledged 1.39 young per nesting pair. All three species nested earlier in 2004 than in 2003; in addition, the overall nesting density of these three species almost doubled from 2003 (1.45 pairs/km2) to 2004 (2.71 pairs/km2). Estimated productivity of all three species was within the ranges reported from other studies. Given extensive and progressive habitat alteration in some areas of south Texas, and the limited distributions of White-tailed Hawks and Crested Caracaras, the presence of large ranches managed for free-range cattle production and hunting leases likely provides important habitat and may be key areas for conservation of these two species. ?? 2009 The Raptor Research Foundation, Inc.

  14. Ecotoxicity of Mine Tailings: Unrehabilitated Versus Rehabilitated.

    PubMed

    Maboeta, M S; Oladipo, O G; Botha, S M

    2018-05-01

    Earthworms are bioindicators of soil pollution. The ecotoxicity of tailings from selected gold mines in South Africa was investigated utilizing Eisenia andrei bioassays and biomarkers. Samples were obtained from unrehabilitated, rehabilitated and naturally vegetated sites. Biomass, neutral red retention time (NRRT), survival and reproduction were assessed using standardized protocols. Earthworm biomass, NRRT and reproductive success in rehabilitated tailings (comparable to naturally vegetated site) were significantly higher (p < 0.05) than in unrehabilitated tailings. In addition, significantly lower (p < 0.05) body tissue concentrations of As, Cd, Co, Cu and Ni contents were found in the rehabilitated tailings compared to the unrehabilitated. Further, significantly lower (p < 0.05) soil Mn and Zn concentrations were obtained in unrehabilitated tailings than the rehabilitated and naturally vegetated sites. Overall, reduced ecotoxicity effects were confirmed in rehabilitated compared to unrehabilitated tailings. This suggests that rehabilitation as a post-mining restorative strategy has strong positive influence on mine tailings.

  15. Orthopoxvirus variola infection of Cynomys ludovicianus (North American black tailed prairie dog).

    PubMed

    Carroll, Darin S; Olson, Victoria A; Smith, Scott K; Braden, Zach H; Patel, Nishi; Abel, Jason; Li, Yu; Damon, Inger K; Karem, Kevin L

    2013-09-01

    Since the eradication of Smallpox, researchers have attempted to study Orthopoxvirus pathogenesis and immunity in animal models in order to correlate results human smallpox. A solely human pathogen, Orthopoxvirus variola fails to produce authentic smallpox illness in any other animal species tested to date. In 2003, an outbreak in the USA of Orthopoxvirus monkeypox, revealed the susceptibility of the North American black-tailed prairie dog (Cynomys ludovicianus) to infection and fulminate disease. Prairie dogs infected with Orthopoxvirus monkeypox present with a clinical scenario similar to ordinary smallpox, including prodrome, rash, and high mortality. This study examines if Black-tailed prairie dogs can become infected with O. variola and serve as a surrogate model for the study of human smallpox disease. Substantive evidence of infection is found in immunological seroconversion of animals to either intranasal or intradermal challenges with O. variola, but in the absence of overt illness. Published by Elsevier Inc.

  16. Wu-Tou Decoction in Rheumatoid Arthritis: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation

    PubMed Central

    Guo, Qingqing; Zheng, Kang; Fan, Danping; Zhao, Yukun; Li, Li; Bian, Yanqin; Qiu, Xuemei; Liu, Xue; Zhang, Ge; Ma, Chaoying; He, Xiaojuan; Lu, Aiping

    2017-01-01

    Purpose: This study aimed to explore underlying action mechanism of Wu-Tou decoction (WTD) in rheumatoid arthritis (RA) through network pharmacology prediction and experimental verification. Methods: Chemical compounds and human target proteins of WTD as well as RA-related human genes were obtained from TCM Database @ Taiwan, PubChem and GenBank, respectively. Subsequently, molecular networks and canonical pathways presumably involved in the treatment of WTD on RA were generated by ingenuity pathway analysis (IPA) software. Furthermore, experimental validation was carried out with MIP-1β-induced U937 cell model and collagen induced arthritis (CIA) rat model. Results: CCR5 signaling pathway in macrophages was shown to be the top one shared signaling pathway associated with both cell immune response and cytokine signaling. In addition, protein kinase C (PKC) δ and p38 in this pathway were treated as target proteins of WTD in RA. In vitro experiments indicated that WTD inhibited MIP-1β-induced production of TNF-α, MIP-1α, and RANTES as well as phosphorylation of CCR5, PKC δ, and p38 in U937 cells. WTD treatment maintained the inhibitory effects on production of TNF-α and RANTES in MIP-1β-induced U937 cells after CCR5 knockdown. In vivo experiments demonstrated that WTD ameliorated symptoms in CIA rats, decreased the levels of IL-1β, IL-2, IL-6, TNF-α, MIP-1α, MIP-2, RANTES, and IP-10 in serum of CIA rats, as well as mRNA levels of MIP-1α, MIP-2, RANTES, and IP-10 in ankle joints of CIA rats. Furthermore, WTD also lowered the phosphorylation levels of CCR5, PKC δ and p38 in both ankle joints and macrophages in ankle joints from CIA rats. Conclusion: It was demonstrated in this research that WTD played a role in inhibiting inflammatory response in RA which was closely connected with the modulation effect of WTD on CCR5 signaling pathway in macrophages. PMID:28515692

  17. Assessing Risks of Mine Tailing Dam Failures

    NASA Astrophysics Data System (ADS)

    Concha Larrauri, P.; Lall, U.

    2017-12-01

    The consequences of tailings dam failures can be catastrophic for communities and ecosystems in the vicinity of the dams. The failure of the Fundão tailings dam at the Samarco mine in 2015 killed 19 people with severe consequences for the environment. The financial and legal consequences of a tailings dam failure can also be significant for the mining companies. For the Fundão tailings dam, the company had to pay 6 billion dollars in fines and twenty-one executives were charged with qualified murder. There are tenths of thousands of active, inactive, and abandoned tailings dams in the world and there is a need to better understand the hazards posed by these structures to downstream populations and ecosystems. A challenge to assess the risks of tailings dams in a large scale is that many of them are not registered in publicly available databases and there is little information about their current physical state. Additionally, hazard classifications of tailings dams - common in many countries- tend to be subjective, include vague parameter definitions, and are not always updated over time. Here we present a simple methodology to assess and rank the exposure to tailings dams using ArcGIS that removes subjective interpretations. The method uses basic information such as current dam height, storage volume, topography, population, land use, and hydrological data. A hazard rating risk was developed to compare the potential extent of the damage across dams. This assessment provides a general overview of what in the vicinity of the tailings dams could be affected in case of a failure and a way to rank tailings dams that is directly linked to the exposure at any given time. One hundred tailings dams in Minas Gerais, Brazil were used for the test case. This ranking approach could inform the risk management strategy of the tailings dams within a company, and when disclosed, it could enable shareholders and the communities to make decisions on the risks they are taking.

  18. Active Tails Enhance Arboreal Acrobatics in Geckos

    DTIC Science & Technology

    2008-03-18

    the secret to the gecko s arboreal acrobatics includes an active tail. We examine the tail s role during rapid climbing, aerial descent, and gliding. We show that a gecko s tail functions as an emergency fifth leg to prevent falling during rapid climbing. A response initiated by slipping causes the tail tip to push against the vertical surface, thereby preventing pitch-back of the head and upper body. When pitch-back cannot be prevented, geckos avoid falling by placing their tail in a posture similar to a bicycle s kickstand. Should a gecko fall with its back to the

  19. A cis-prenyltransferase from Methanosarcina acetivorans catalyzes both head-to-tail and nonhead-to-tail prenyl condensation.

    PubMed

    Ogawa, Takuya; Emi, Koh-Ichi; Koga, Kazushi; Yoshimura, Tohru; Hemmi, Hisashi

    2016-06-01

    Cis-prenyltransferase usually consecutively catalyzes the head-to-tail condensation reactions of isopentenyl diphosphate to allylic prenyl diphosphate in the production of (E,Z-mixed) polyprenyl diphosphate, which is the precursor of glycosyl carrier lipids. Some recently discovered homologs of the enzyme, however, catalyze the nonhead-to-tail condensation reactions between allylic prenyl diphosphates. In this study, we characterize a cis-prenyltransferase homolog from a methanogenic archaeon, Methanosarcina acetivorans, to obtain information on the biosynthesis of the glycosyl carrier lipids within it. This enzyme catalyzes both head-to-tail and nonhead-to-tail condensation reactions. The kinetic analysis shows that the main reaction of the enzyme is consecutive head-to-tail prenyl condensation reactions yielding polyprenyl diphosphates, while the chain lengths of the major products seem shorter than expected for the precursor of glycosyl carrier lipids. On the other hand, a subsidiary reaction of the enzyme, i.e., nonhead-to-tail condensation between dimethylallyl diphosphate and farnesyl diphosphate, gives a novel diterpenoid compound, geranyllavandulyl diphosphate. © 2016 Federation of European Biochemical Societies.

  20. Management practices used by white-tailed deer farms in Pennsylvania and herd health problems.

    PubMed

    Brooks, Jason W; Jayarao, Bhushan M

    2008-01-01

    To determine current management practices used by white-tailed deer farms in Pennsylvania and identify animal health problems that exist in these herds. Cross-sectional study. Owners and managers of 233 farms in Pennsylvania that raised white-tailed deer. A self-administered questionnaire was mailed to participants. Herds ranged in size from 1 to 350 deer. Land holdings ranged from 0.07 to 607 hectares (0.17 to 1,500 acres). Stocking density ranged from 0.1 to 118.6 deer/hectare (0.04 to 48 deer/acre). Most (84%) respondents raised deer for breeding or hunting stock; 13% raised deer exclusively as pets or for hobby purposes, and purpose varied by herd size. Multiple associations were identified between management or disease factors and herd size. The use of vaccines, use of veterinary and diagnostic services, use of pasture, and use of artificial insemination increased as herd size increased. The most common conditions in herds of all sizes were respiratory tract disease, diarrhea, parasitism, and sudden death. The prevalence of respiratory tract disease increased as herd size increased. Results suggested that many aspects of herd management for white-tailed deer farms in Pennsylvania were associated with herd size, but that regardless of herd size, many preventive medicine practices were improperly used or underused in many herds.

  1. Ecological aspects of microorganisms inhabiting uranium mill tailings

    USGS Publications Warehouse

    Miller, C.L.; Landa, E.R.; Updegraff, D.M.

    1987-01-01

    Numbers and types of microorganisms in uranium mill tailings were determined using culturing techniques. Arthrobacter were found to be the predominant microorganism inhabiting the sandy tailings, whereas Bacillus and fungi predominated in the slime tailings. Sulfate-reducing bacteria, capable of leaching radium, were isolated in low numbers from tailings samples but were isolated in significantly high numbers from topsoil in contact with the tailings. The results are placed in the context of the magnitude of uranium mill tailings in the United States, the hazards posed by the tailings, and how such hazards could be enhanced or diminished by microbial activities. Patterns in the composition of the microbial population are evaluated with respect to the ecological variables that influence microbial growth. ?? 1987 Springer-Verlag New York Inc.

  2. VIRUS ISOLATION AND MOLECULAR DETECTION OF BLUETONGUE AND EPIZOOTIC HEMORRHAGIC DISEASE VIRUSES FROM NATURALLY INFECTED WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS).

    PubMed

    Kienzle, Clara; Poulson, Rebecca L; Ruder, Mark G; Stallknecht, David E

    2017-10-01

    Hemorrhagic disease in North America is caused by multiple serotypes of epizootic hemorrhagic disease virus (EHDV) and bluetongue virus (BTV). Diagnostic tests for detection of EHDV and BTV include virus isolation (VI), reverse transcriptase (RT)-PCR, and real-time RT-PCR (rRT-PCR). Our objective was to compare the diagnostic capabilities of three rRT-PCR protocols for detection of EHDV and BTV from naturally infected white-tailed deer (Odocoileus virginianus). We compared the effectiveness of these assays to traditional viral detection methods (e.g., VI) for historic and current clinical cases. Because of the variable nature of tissue collection and storage before diagnostic testing, an evaluation of viral persistence on multiple freeze-thaw events was also conducted. Two of the rRT-PCR assays provided for reliable detection of EHDV and BTV from 100% of clinically affected and VI-confirmed infected animals. Additionally, no significant change in viral titer was observed on multiple freeze-thaw events.

  3. The X-ray Crystal Structure of the Phage Tail Terminator Protein Reveals the Biologically Relevant Hexameric Rang Structure and Demonstrates a Conserved mechanism of Tail Termination among Divrse Long Tailed Phages

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pell, L.; Liu, A; Edmonds, L

    The tail terminator protein (TrP) plays an essential role in phage tail assembly by capping the rapidly polymerizing tail once it has reached its requisite length and serving as the interaction surface for phage heads. Here, we present the 2.7-A crystal structure of a hexameric ring of gpU, the TrP of phage ?. Using sequence alignment analysis and site-directed mutagenesis, we have shown that this multimeric structure is biologically relevant and we have delineated its functional surfaces. Comparison of the hexameric crystal structure with the solution structure of gpU that we previously solved using NMR spectroscopy shows large structural changesmore » occurring upon multimerization and suggests a mechanism that allows gpU to remain monomeric at high concentrations on its own, yet polymerize readily upon contact with an assembled tail tube. The gpU hexamer displays several flexible loops that play key roles in head and tail binding, implying a role for disorder-to-order transitions in controlling assembly as has been observed with other ? morphogenetic proteins. Finally, we have found that the hexameric structure of gpU is very similar to the structure of a putative TrP from a contractile phage tail even though it displays no detectable sequence similarity. This finding coupled with further bioinformatic investigations has led us to conclude that the TrPs of non-contractile-tailed phages, such as ?, are evolutionarily related to those of contractile-tailed phages, such as P2 and Mu, and that all long-tailed phages may utilize a conserved mechanism for tail termination.« less

  4. Atmospheric pressure plasma accelerates tail regeneration in tadpoles Xenopus laevis

    NASA Astrophysics Data System (ADS)

    Rivie, A.; Martus, K.; Menon, J.

    2017-08-01

    Atmospheric pressure plasma is a partially ionized gas composed of neutral and charged particles, including electrons and ions, as well as reactive oxygen species (ROS). Recently, it is utilized as possible therapy in oncology, sterilization, skin diseases, wound healing and tissue regeneration. In this study we focused on effect of plasma exposure on tail regeneration of tadpoles, Xenopus leavis with special emphasis on role of ROS, antioxidant defenses and morphological features of the regenerate. When amputated region of the tail was exposed to the helium plasma it resulted in a faster rate of growth, elevated ROS and increase in antioxidant enzymes in the regenerate compared to that of untreated control. An increase in nitric oxide (free radical) as well as activity of nitric oxide synthase(s) were observed once the cells of the regeneration blastema - a mass of proliferating cells are ready for differentiation. Microscopically the cells of the regenerate of plasma treated tadpoles show altered morphology and characteristics of cellular hypoxia and oxidative stress. We summarize that plasma exposure accelerates the dynamics of wound healing and tail regeneration through its effects on cell proliferation and differentiation as well as angiogenesis mediated through ROS signaling.

  5. Telling tails explain the discrepancy in sexual partner reports.

    PubMed

    Morris, M

    1993-09-30

    An anomaly often noted in surveys of sexual behaviour is that the number of female sexual partners reported by men exceeds the number of male partners reported by women. This discrepancy is sometimes interpreted as evidence that surveys produce unreliable data due to sex-linked response and sampling bias. We report here that among the 90% of respondents reporting fewer than 20 lifetime partners, however, the ratio of male to female reports drops from 3.2:1 to 1.2:1. The anomaly thus appears to be driven by the upper tail of the contact distribution, an example of the general principle of outlier influence in data analysis. The implication is that sexual behaviour surveys provide reliable data in the main, and that simple improvements can increase precision in the upper tail to make these data more useful for modelling the spread of AIDS and other sexually transmitted diseases.

  6. Long-Tailed Distributions in Biological Systems:. Revisit to Lognormals

    NASA Astrophysics Data System (ADS)

    Kobayashi, N.; Kohyama, K.; Moriyama, O.; Sasaki, Y.; Matsushita, M.; Matsushita, S.

    2007-07-01

    Long-tailed distributions in biological systems have been studied. First, we found that lognormal distributions show excellent fit with various data for the duration distribution of disability in aged people, irrespective of their severity and gender. The robust lognormal distribution of disability implies that the incidence of diseases can be completed by many independent subprocesses in succession. Next, we studied food fragmentation by human mastication. A lognormal distribution well fits to the entire region for masticated food fragments for a small number of chewing strokes. Furthermore, the tail of the fragment-size distribution changes from the lognormal distribution to a power-law one as the chewing stroke number increases. The good data fitting by the lognormal and power-law distribution implies that two functions of mastication, a sequential fragmentation with cascade and randomness and a lower threshold for fragment size, may affect the size distribution of masticated food fragments.

  7. From the field: Efficacy of detecting Chronic Wasting Disease via sampling hunter-killed white-tailed deer

    USGS Publications Warehouse

    Diefenbach, D.R.; Rosenberry, C.S.; Boyd, Robert C.

    2004-01-01

    Surveillance programs for Chronic Wasting Disease (CWD) in free-ranging cervids often use a standard of being able to detect 1% prevalence when determining minimum sample sizes. However, 1% prevalence may represent >10,000 infected animals in a population of 1 million, and most wildlife managers would prefer to detect the presence of CWD when far fewer infected animals exist. We wanted to detect the presence of CWD in white-tailed deer (Odocoileus virginianus) in Pennsylvania when the disease was present in only 1 of 21 wildlife management units (WMUs) statewide. We used computer simulation to estimate the probability of detecting CWD based on a sampling design to detect the presence of CWD at 0.1% and 1.0% prevalence (23-76 and 225-762 infected deer, respectively) using tissue samples collected from hunter-killed deer. The probability of detection at 0.1% prevalence was <30% with sample sizes of ???6,000 deer, and the probability of detection at 1.0% prevalence was 46-72% with statewide sample sizes of 2,000-6,000 deer. We believe that testing of hunter-killed deer is an essential part of any surveillance program for CWD, but our results demonstrated the importance of a multifaceted surveillance approach for CWD detection rather than sole reliance on testing hunter-killed deer.

  8. On the average configuration of the geomagnetic tail

    NASA Technical Reports Server (NTRS)

    Fairfield, D. H.

    1978-01-01

    Over 3000 hours of IMP-6 magnetic field data obtained between 20 and 33 R sub E in the geomagnetic tail have been used in a statistical study of the tail configuration. A distribution of 2.5 minute averages of B sub Z as a function of position across the tail reveals that more flux crosses the equatorial plane near the dawn and dusk flanks than near midnight. The tail field projected in the solar magnetospheric equatorial plane deviates from the X axis due to flaring and solar wind aberration by an angle alpha = -0.9 y sub SM - 1.7 where Y sub SM is in earth radii and alpha is in degrees. After removing these effects the Y component of the tail field is found to depend on interplanetary sector structure. During an away sector the B sub Y component of the tail field is on average 0.5 gamma greater than that during a toward sector, a result that is true in both tail lobes and is independent of location across the tail.

  9. RADIOGRAPHIC AND ULTRASONOGRAPHIC ABDOMINAL ANATOMY IN CAPTIVE RING-TAILED LEMURS (LEMUR CATTA).

    PubMed

    Makungu, Modesta; du Plessis, Wencke M; Barrows, Michelle; Groenewald, Hermanus B; Koeppel, Katja N

    2016-06-01

    The ring-tailed lemur (Lemur catta) is primarily distributed in south and southwestern Madagascar. It is classified as an endangered species by the International Union for Conservation of Nature. Various abdominal diseases, such as hepatic lipidosis, intestinal ulcers, cystitis, urinary tract obstruction, and neoplasia (e.g., colonic adenocarcinoma and cholangiocarcinoma), have been reported in this species. The aim of this study was to describe the normal radiographic and ultrasonographic abdominal anatomy in captive ring-tailed lemurs to provide guidance for clinical use. Radiography of the abdomen and ultrasonography of the liver, spleen, kidneys, and urinary bladder were performed in 13 and 9 healthy captive ring-tailed lemurs, respectively, during their annual health examinations. Normal radiographic and ultrasonographic reference ranges for abdominal organs were established and ratios were calculated. The majority (12/13) of animals had seven lumbar vertebrae. The sacrum had mainly (12/13) three segments. Abdominal serosal detail was excellent in all animals, and hypaxial muscles were conspicuous in the majority (11/13) of animals. The spleen was frequently (12/13) seen on the ventrodorsal (VD) view and rarely (3/13) on the right lateral (RL) view. The liver was less prominent and well contained within the ribcage. The pylorus was mostly (11/13) located to the right of the midline. The right and left kidneys were visible on the RL and VD views, with the right kidney positioned more cranial and dorsal to the left kidney. On ultrasonography, the kidneys appeared ovoid on transverse and longitudinal views. The medulla was hypoechoic to the renal cortex. The renal cortex was frequently (8/9) isoechoic and rarely (1/9) hyperechoic to the splenic parenchyma. The liver parenchyma was hypoechoic (5/5) to the renal cortex. Knowledge of the normal radiographic and ultrasonographic abdominal anatomy of ring-tailed lemurs may be useful in the diagnosis of diseases and in

  10. Tail Shape Design of Boat Wind Turbines

    NASA Astrophysics Data System (ADS)

    Singamsitty, Venkatesh

    Wind energy is a standout among the most generally utilized sustainable power source assets. A great deal of research and improvements have been happening in the wind energy field. Wind turbines are mechanical devices that convert kinetic energy into electrical power. Boat wind turbines are for the small-scale generation of electric power. In order to catch wind energy effectively, boat wind turbines need to face wind direction. Tails are used in boat wind turbines to alter the wind turbine direction and receive the variation of the incoming direction of wind. Tails are used to change the performance of boat wind turbines in an effective way. They are required to generate a quick and steady response as per change in wind direction. Tails can have various shapes, and their effects on boat wind turbines are different. However, the effects of tail shapes on the performance of boat wind turbines are not thoroughly studied yet. In this thesis, five tail shapes were studied. Their effects on boat wind turbines were investigated. The power extracted by the turbines from the air and the force acting on the boat wind turbine tail were analyzed. The results of this thesis provide a guideline of tail shape design for boat wind turbines.

  11. Work-Centered Technology Development (WTD)

    DTIC Science & Technology

    2005-03-01

    theoretical, testable, inductive, and repeatable foundations of science. o Theoretical foundations include notions such as statistical versus analytical...Human Factors and Ergonomics Society, 263-267. 179 Eggleston, R. G. (2005). Coursebook : Work-Centered Design (WCD). AFRL/HECS WCD course training

  12. Quasi-steady state aerodynamics of the cheetah tail

    PubMed Central

    Boje, Edward; Fisher, Callen; Louis, Leeann; Lane, Emily

    2016-01-01

    ABSTRACT During high-speed pursuit of prey, the cheetah (Acinonyx jubatus) has been observed to swing its tail while manoeuvring (e.g. turning or braking) but the effect of these complex motions is not well understood. This study demonstrates the potential of the cheetah's long, furry tail to impart torques and forces on the body as a result of aerodynamic effects, in addition to the well-known inertial effects. The first-order aerodynamic forces on the tail are quantified through wind tunnel testing and it is observed that the fur nearly doubles the effective frontal area of the tail without much mass penalty. Simple dynamic models provide insight into manoeuvrability via simulation of pitch, roll and yaw tail motion primitives. The inertial and quasi-steady state aerodynamic effects of tail actuation are quantified and compared by calculating the angular impulse imparted onto the cheetah's body and its shown aerodynamic effects contribute to the tail's angular impulse, especially at the highest forward velocities. PMID:27412267

  13. Wing-Fuselage Interference, Tail Buffeting, and Air Flow About the Tail of a Low-Wing Monoplane

    NASA Technical Reports Server (NTRS)

    White, James A; Hood, Manley J

    1935-01-01

    This report presents the results of wind tunnel tests on a Mcdonnell Douglas airplane to determine the wing-fuselage interference of a low-wing monoplane. The tests included a study of tail buffeting and the air flow in the region of the tail. The airplane was tested with and without the propeller slipstream, both in the original condition and with several devices designed to reduce or eliminate tail buffeting. The devices used were wing-fuselage fillets, a NACA cowling, reflexed trailing edge of the wing, and stub auxiliary airfoils.

  14. Four tails problems for dynamical collapse theories

    NASA Astrophysics Data System (ADS)

    McQueen, Kelvin J.

    2015-02-01

    The primary quantum mechanical equation of motion entails that measurements typically do not have determinate outcomes, but result in superpositions of all possible outcomes. Dynamical collapse theories (e.g. GRW) supplement this equation with a stochastic Gaussian collapse function, intended to collapse the superposition of outcomes into one outcome. But the Gaussian collapses are imperfect in a way that leaves the superpositions intact. This is the tails problem. There are several ways of making this problem more precise. But many authors dismiss the problem without considering the more severe formulations. Here I distinguish four distinct tails problems. The first (bare tails problem) and second (structured tails problem) exist in the literature. I argue that while the first is a pseudo-problem, the second has not been adequately addressed. The third (multiverse tails problem) reformulates the second to account for recently discovered dynamical consequences of collapse. Finally the fourth (tails problem dilemma) shows that solving the third by replacing the Gaussian with a non-Gaussian collapse function introduces new conflict with relativity theory.

  15. What a wish to die can mean: reasons, meanings and functions of wishes to die, reported from 30 qualitative case studies of terminally ill cancer patients in palliative care.

    PubMed

    Ohnsorge, Kathrin; Gudat, Heike; Rehmann-Sutter, Christoph

    2014-01-01

    Despite research efforts over recent decades to deepen our understanding of why some terminally ill patients express a wish to die (WTD), there is broad consensus that we need more detailed knowledge about the factors that might influence such a wish. The objective of this study is to explore the different possible motivations and explanations of patients who express or experience a WTD. Thirty terminally ill cancer patients, their caregivers and relatives; from a hospice, a palliative care ward in the oncology department of a general hospital, and an ambulatory palliative care service; 116 semi-structured qualitative interviews analysed using a complementary grounded theory and interpretive phenomenological analysis approach. THREE DIMENSIONS WERE FOUND TO BE CRUCIAL FOR UNDERSTANDING AND ANALYSING WTD STATEMENTS: intentions, motivations and social interactions. This article analyses the motivations of WTD statements. Motivations can further be differentiated into (1) reasons, (2) meanings and (3) functions. Reasons are the factors that patients understand as causing them to have or accounting for having a WTD. These reasons can be ordered along the bio-psycho-socio-spiritual model. Meanings describe the broader explanatory frameworks, which explain what this wish means to a patient. Meanings are larger narratives that reflect personal values and moral understandings and cannot be reduced to reasons. Functions describe the effects of the WTD on patients themselves or on others, conscious or unconscious, that might be part of the motivation for a WTD. Nine typical 'meanings' were identified in the study, including "to let death put an end to severe suffering", "to move on to another reality", and - more frequently- "to spare others from the burden of oneself". The distinction between reasons, meanings and functions allows for a more detailed understanding of the motivation for the WTD statements of cancer patients in palliative care situations. Better understanding

  16. Some Effects of Horizontal-Tail Position on the Vertical-Tail Pressure Distributions of a Complete Model in Sideslip at High Subsonic Speeds

    NASA Technical Reports Server (NTRS)

    Alford, William J., Jr.

    1958-01-01

    An investigation has been made in the Langley high-speed 7- by 10-foot tunnel of some effects of horizontal-tail position on the vertical-tail pressure distributions of a complete model in sideslip at high subsonic speeds. The wing of the model was swept back 28.82 deg at the quarter-chord line and had an aspect ratio of 3.50, a taper ratio of 0.067, and NACA 65A004 airfoil sections parallel to the model plane of symmetry. Tests were made with the horizontal tail off, on the wing-chord plane extended, and in T-tail arrangements in forward and rearward locations. The test Mach numbers ranged from 0.60 to 0.92, which corresponds to a Reynolds number range from approximately 2.93 x 10(exp 6) to 3.69 x 10(exp 6), based on the wing mean aerodynamic chord. The sideslip angles varied from -3.9 deg to 12.7 deg at several selected angles of attack. The results indicated that, for a given angle of sideslip, increases in angle of attack caused reductions in the vertical-tail loads in the vicinity of the root chord and increases at the midspan and tip locations, with rearward movements in the local chordwise centers of pressure for the midspan locations and forward movements near the tip of the vertical tail. At the higher angles of attack all configurations investigated experienced outboard and rearward shifts in the center of pressure of the total vertical-tail load. Location of the horizontal tail on the wing- chord plane extended produced only small effects on the vertical-tail loads and centers of pressure. Locating the horizontal tail at the tip of the vertical tail in the forward position caused increases in the vertical-tail loads; this configuration, however, experienced considerable reduction in loads with increasing Mach number. Location of the horizontal tail at the tip of the vertical tail in the rearward position produced the largest increases in vertical-tail loads per degree sideslip angle; this configuration experienced the smallest variations of loads with

  17. The Distant Sodium Tail of Mercury

    NASA Technical Reports Server (NTRS)

    Potter, A. E.; Killen, R. M.; Morgan, T. H.

    2001-01-01

    Models of the sodium atmosphere of Mercury predict the possible existence of a cornet-like sodium tail. Detection and mapping of the predicted sodium tail would provide quantitative data on the energy of the process that produces sodium atoms from the planetary surface. Previous efforts to detect the sodium tail by means of observations done during daylight hours have been only partially successful because scattered sunlight obscured the weak sodium emissions in the tail. However, at greatest eastern elongation around the March equinox in the northern hemisphere, Mercury can be seen as an evening star in astronomical twilight. At this time, the intensity of scattered sunlight is low enough that sodium emissions as low as 500 Rayleighs can be detected. Additional information is contained in the original extended abstract.

  18. Detection of Mercury's Potassium Tail

    NASA Astrophysics Data System (ADS)

    Schmidt, Carl; Leblanc, Francois; Moore, Luke; Bida, Thomas A.

    2017-10-01

    Ground-based observations of Mercury's exosphere bridge the gap between the MESSENGER and BepiColombo missions and provide a broad counterpart to their in situ measurements. Here we report the first detection of Mercury's potassium tail in both emission lines of the D doublet. The sodium to potassium abundance ratio at 5 planetary radii down-tail is approximately 95, near the mid-point of a wide range of values that have been quoted over the planet's disk. This is several times the Na/K present in atmospheres of the Galilean satellites and more than an order of magnitude above Mercury's usual analogue, the Moon. The observations confirm that Mercury's anomalously high Na/K ratios cannot be explained by differences in neutral loss rates. The width and structure of the Na and K tails is comparable and both exhibit a persistent enhancement in their northern lobe. We interpret this as a signature of Mercury's offset magnetosphere; the exosphere's source rates are locally enhanced at the southern surface, and sloshing from radiation pressure and gravity guides this population into the northern region of the tail.

  19. Immune responses to HTLV-I(ACH) during acute infection of pig-tailed macaques.

    PubMed

    McGinn, Therese M; Wei, Qing; Stallworth, Jackie; Fultz, Patricia N

    2004-04-01

    Human T cell lymphotropic virus type 1 (HTLV-I) is causally linked to adult T cell leukemia/lymphoma (ATL) and a chronic progressive neurological disease, HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). A nonhuman primate model that reproduces disease symptoms seen in HTLV-I-infected humans might facilitate identification of initial immune responses to the virus and an understanding of pathogenic mechanisms in HTLV-I-related disease. Previously, we showed that infection of pig-tailed macaques with HTLV-I(ACH) is associated with multiple signs of disease characteristic of both HAM/TSP and ATL. We report here that within the first few weeks after HTLV-I(ACH) infection of pig-tailed macaques, serum concentrations of interferon (IFN)-alpha increased and interleukin-12 decreased transiently, levels of nitric oxide were elevated, and activation of CD4(+) and CD8(+) lymphocytes and CD16(+) natural killer cells in peripheral blood were observed. HTLV-I(ACH) infection elicited virus-specific antibodies in all four animals within 4 to 6 weeks; however, Tax-specific lymphoproliferative responses were not detected until 25-29 weeks after infection in all four macaques. IFN-gamma production by peripheral blood cells stimulated with a Tax or Gag peptide was detected to varying degrees in all four animals by ELISPOT assay. Peripheral blood lymphocytes from one animal that developed only a marginal antigen-specific cellular response were unresponsive to mitogen stimulation during the last few weeks preceding its death from a rapidly progressive disease syndrome associated with HTLV-I(ACH) infection of pig-tailed macaques. The results show that during the first few months after HTLV-I(ACH) infection, activation of both innate and adaptive immunity, limited virus-specific cellular responses, sustained immune system activation, and, in some cases, immunodeficiency were evident. Thus, this animal model might be valuable for understanding early stages of infection

  20. Black-tailed and white-tailed jackrabbits in the American West: History, ecology, ecological significance, and survey methods

    USGS Publications Warehouse

    Simes, Matthew; Longshore, Kathleen M.; Nussear, Kenneth E.; Beatty, Greg L.; Brown, David E.; Esque, Todd C.

    2015-01-01

    Across the western United States, Leporidae are the most important prey item in the diet of Golden Eagles (Aquila chrysaetos). Leporids inhabiting the western United States include black-tailed (Lepus californicus) and white-tailed jackrabbits (Lepus townsendii) and various species of cottontail rabbit (Sylvilagus spp.). Jackrabbits (Lepus spp.) are particularly important components of the ecological and economic landscape of western North America because their abundance influences the reproductive success and population trends of predators such as coyotes (Canis latrans), bobcats (Lynx rufus), and a number of raptor species. Here, we review literature pertaining to black-tailed and white-tailed jackrabbits comprising over 170 published journal articles, notes, technical reports, conference proceedings, academic theses and dissertations, and other sources dating from the late 19th century to the present. Our goal is to present information to assist those in research and management, particularly with regard to protected raptor species (e.g., Golden Eagles), mammalian predators, and ecological monitoring. We classified literature sources as (1) general information on jackrabbit species, (2) black-tailed or (3) white-tailed jackrabbit ecology and natural history, or (4) survey methods. These categories, especially 2, 3, and 4, were further subdivided as appropriate. The review also produced several tables on population trends, food habits, densities within various habitats, and jackrabbit growth and development. Black-tailed and white-tailed jackrabbits are ecologically similar in general behaviors, use of forms, parasites, and food habits, and they are prey to similar predators; but they differ in their preferred habitats. While the black-tailed jackrabbit inhabits agricultural land, deserts, and shrublands, the white-tailed jackrabbit is associated with prairies, alpine tundra, and sagebrush-steppe. Frequently considered abundant, jackrabbit numbers in western North

  1. Heavy Tail Behavior of Rainfall Extremes across Germany

    NASA Astrophysics Data System (ADS)

    Castellarin, A.; Kreibich, H.; Vorogushyn, S.; Merz, B.

    2017-12-01

    Distributions are termed heavy-tailed if extreme values are more likely than would be predicted by probability distributions that have exponential asymptotic behavior. Heavy-tail behavior often leads to surprise, because historical observations can be a poor guide for the future. Heavy-tail behavior seems to be widespread for hydro-meteorological extremes, such as extreme rainfall and flood events. To date there have been only vague hints to explain under which conditions these extremes show heavy-tail behavior. We use an observational data set consisting of 11 climate variables at 1440 stations across Germany. This homogenized, gap-free data set covers 110 years (1901-2010) at daily resolution. We estimate the upper tail behavior, including its uncertainty interval, of daily precipitation extremes for the 1,440 stations at the annual and seasonal time scales. Different tail indicators are tested, including the shape parameter of the Generalized Extreme Value distribution, the upper tail ratio and the obesity index. In a further step, we explore to which extent the tail behavior can be explained by geographical and climate factors. A large number of characteristics is derived, such as station elevation, degree of continentality, aridity, measures for quantifying the variability of humidity and wind velocity, or event-triggering large-scale atmospheric situation. The link between the upper tail behavior and these characteristics is investigated via data mining methods capable of detecting non-linear relationships in large data sets. This exceptionally rich observational data set, in terms of number of stations, length of time series and number of explaining variables, allows insights into the upper tail behavior which is rarely possible given the typical observational data sets available.

  2. Quasi-steady state aerodynamics of the cheetah tail.

    PubMed

    Patel, Amir; Boje, Edward; Fisher, Callen; Louis, Leeann; Lane, Emily

    2016-08-15

    During high-speed pursuit of prey, the cheetah (Acinonyx jubatus) has been observed to swing its tail while manoeuvring (e.g. turning or braking) but the effect of these complex motions is not well understood. This study demonstrates the potential of the cheetah's long, furry tail to impart torques and forces on the body as a result of aerodynamic effects, in addition to the well-known inertial effects. The first-order aerodynamic forces on the tail are quantified through wind tunnel testing and it is observed that the fur nearly doubles the effective frontal area of the tail without much mass penalty. Simple dynamic models provide insight into manoeuvrability via simulation of pitch, roll and yaw tail motion primitives. The inertial and quasi-steady state aerodynamic effects of tail actuation are quantified and compared by calculating the angular impulse imparted onto the cheetah's body and its shown aerodynamic effects contribute to the tail's angular impulse, especially at the highest forward velocities. © 2016. Published by The Company of Biologists Ltd.

  3. Iron-mediated soil carbon response to water-table decline in an alpine wetland

    PubMed Central

    Wang, Yiyun; Wang, Hao; He, Jin-Sheng; Feng, Xiaojuan

    2017-01-01

    The tremendous reservoir of soil organic carbon (SOC) in wetlands is being threatened by water-table decline (WTD) globally. However, the SOC response to WTD remains highly uncertain. Here we examine the under-investigated role of iron (Fe) in mediating soil enzyme activity and lignin stabilization in a mesocosm WTD experiment in an alpine wetland. In contrast to the classic ‘enzyme latch’ theory, phenol oxidative activity is mainly controlled by ferrous iron [Fe(II)] and declines with WTD, leading to an accumulation of dissolvable aromatics and a reduced activity of hydrolytic enzyme. Furthermore, using dithionite to remove Fe oxides, we observe a significant increase of Fe-protected lignin phenols in the air-exposed soils. Fe oxidation hence acts as an ‘iron gate’ against the ‘enzyme latch’ in regulating wetland SOC dynamics under oxygen exposure. This newly recognized mechanism may be key to predicting wetland soil carbon storage with intensified WTD in a changing climate. PMID:28649988

  4. Iron-mediated soil carbon response to water-table decline in an alpine wetland

    NASA Astrophysics Data System (ADS)

    Wang, Yiyun; Wang, Hao; He, Jin-Sheng; Feng, Xiaojuan

    2017-06-01

    The tremendous reservoir of soil organic carbon (SOC) in wetlands is being threatened by water-table decline (WTD) globally. However, the SOC response to WTD remains highly uncertain. Here we examine the under-investigated role of iron (Fe) in mediating soil enzyme activity and lignin stabilization in a mesocosm WTD experiment in an alpine wetland. In contrast to the classic `enzyme latch' theory, phenol oxidative activity is mainly controlled by ferrous iron [Fe(II)] and declines with WTD, leading to an accumulation of dissolvable aromatics and a reduced activity of hydrolytic enzyme. Furthermore, using dithionite to remove Fe oxides, we observe a significant increase of Fe-protected lignin phenols in the air-exposed soils. Fe oxidation hence acts as an `iron gate' against the `enzyme latch' in regulating wetland SOC dynamics under oxygen exposure. This newly recognized mechanism may be key to predicting wetland soil carbon storage with intensified WTD in a changing climate.

  5. The Sodium Tail of the Moon

    NASA Technical Reports Server (NTRS)

    Matta, M.; Smith, S.; Baumgardner, J.; Wilson, J.; Martinis, C.; Mendillo, M.

    2009-01-01

    During the few days centered about new Moon, the lunar surface is optically hidden from Earth-based observers. However, the Moon still offers an observable: an extended sodium tail. The lunar sodium tail is the escaping "hot" component of a coma-like exosphere of sodium generated by photon-stimulated desorption, solar wind sputtering and meteoroid impact. Neutral sodium atoms escaping lunar gravity experience solar radiation pressure that drives them into the anti-solar direction forming a comet-like tail. During new Moon time, the geometry of the Sun, Moon and Earth is such that the anti-sunward sodium flux is perturbed by the terrestrial gravitational field resulting in its focusing into a dense core that extends beyond the Earth. An all-sky camera situated at the El Leoncito Observatory (CASLEO) in Argentina has been successfully imaging this tail through a sodium filter at each lunation since April 2006. This paper reports on the results of the brightness of the lunar sodium tail spanning 31 lunations between April 2006 and September 2008. Brightness variability trends are compared with both sporadic and shower meteor activity, solar wind proton energy flux and solar near ultra violet (NUV) patterns for possible correlations. Results suggest minimal variability in the brightness of the observed lunar sodium tail, generally uncorrelated with any single source, yet consistent with a multi-year period of minimal solar activity and non-intense meteoric fluxes.

  6. Physical space and long-tail markets

    NASA Astrophysics Data System (ADS)

    Bentley, R. Alexander; Madsen, Mark E.; Ormerod, Paul

    2009-03-01

    The Internet is known to have had a powerful impact on on-line retailer strategies in markets characterised by long-tail distribution of sales [C. Anderson, Long Tail: Why the Future of Business is Selling Less of More, Hyperion, New York, 2006]. Such retailers can exploit the long tail of the market, since they are effectively without physical limit on the number of choices on offer. Here we examine two extensions of this phenomenon. First, we introduce turnover into the long-tail distribution of sales. Although over any given period such as a week or a month, the distribution is right-skewed and often power law distributed, over time there is considerable turnover in the rankings of sales of individual products. Second, we establish some initial results on the implications for shelf-space and physical retailers in such markets.

  7. Metal mobilization under alkaline conditions in ash-covered tailings.

    PubMed

    Lu, Jinmei; Alakangas, Lena; Wanhainen, Christina

    2014-06-15

    The aim of this study was to determine element mobilization and accumulation in mill tailings under alkaline conditions. The tailings were covered with 50 cm of fly ash, and above a sludge layer. The tailings were geochemically and mineralogically investigated. Sulfides, such as pyrrhotite, sphalerite and galena along with gangue minerals such as dolomite, calcite, micas, chlorite, epidote, Mn-pyroxene and rhodonite were identified in the unoxidized tailings. The dissolution of the fly ash layer resulted in a high pH (close to 12) in the underlying tailings. This, together with the presence of organic matter, increased the weathering of the tailings and mobilization of elements in the uppermost 47 cm of the tailings. All primary minerals were depleted, except quartz and feldspar which were covered by blurry secondary carbonates. Sulfide-associated elements such as Cd, Fe, Pb, S and Zn and silicate-associated elements such as Fe, Mg and Mn were released from the depletion zone and accumulated deeper down in the tailings where the pH decreased to circum-neutral. Sequential extraction suggests that Cd, Cu, Fe, Pb, S and Zn were retained deeper down in the tailings and were mainly associated with the sulfide phase. Calcium, Cr, K and Ni released from the ash layer were accumulated in the uppermost depletion zone of the tailings. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Vertical Tail Buffeting Alleviation Using Piezoelectric Actuators-Some Results of the Actively Controlled Response of Buffet-Affected Tails (ACROBAT) Program

    NASA Technical Reports Server (NTRS)

    Moses, Robert W.

    1997-01-01

    Buffet is an aeroelastic phenomenon associated with high performance aircraft especially those with twin vertical tails. In particular, for the F/A-18 aircraft at high angles of attack, vortices emanating from wing/fuselage leading edge extensions burst, immersing the vertical tails in their wake. The resulting buffet loads on the vertical tails are a concern from fatigue and inspection points of view. Recently, a 1/6-scale F-18 wind-tunnel model was tested in the Transonic Dynamics Tunnel at the NASA Langley Research Center as part of the Actively Controlled Response Of Buffet Affected Tails (ACROBAT) Program to assess the use of active controls in reducing vertical tail buffeting. The starboard vertical tail was equipped with an active rudder and the port vertical tail was equipped with piezoelectric actuators. The tunnel conditions were atmospheric air at Mach 0.10. By using single-input-single-output control laws at gains well below the physical limits of the actuators, the power spectral density of the root strains at the frequency of the first bending mode of the vertical tail was reduced by as much as 60 percent up to angles of attack of 37 degrees. Root mean square (RMS) values of root strain were reduced by as much as 19 percent. The results herein illustrate that buffet alleviation of vertical tails can be accomplished using simple active control of the rudder or piezoelectric actuators. In fact, as demonstrated herein, a fixed gain single input single output control law that commands piezoelectric actuators may be active throughout the high angle-of-attack maneuver without requiring any changes during the maneuver. Future tests are mentioned for accentuating the international interest in this area of research.

  9. Ecological restoration alters microbial communities in mine tailings profiles

    NASA Astrophysics Data System (ADS)

    Li, Yang; Jia, Zhongjun; Sun, Qingye; Zhan, Jing; Yang, Yang; Wang, Dan

    2016-04-01

    Ecological restoration of mine tailings have impact on soil physiochemical properties and microbial communities. The surface soil has been a primary concern in the past decades, however it remains poorly understood about the adaptive response of microbial communities along the profile during ecological restoration of the tailings. In this study, microbial communities along a 60-cm profile were investigated in a mine tailing pond during ecological restoration of the bare waste tailings (BW) with two vegetated soils of Imperata cylindrica (IC) and Chrysopogon zizanioides (CZ) plants. Revegetation of both IC and CZ could retard soil degradation of mine tailing by stimulation of soil pH at 0-30 cm soils and altered the bacterial communities at 0-20 cm depths of the mine tailings. Significant differences existed in the relative abundance of the phyla Alphaproteobacteria, Deltaproteobacteria, Acidobacteria, Firmicutes and Nitrospira. Slight difference of bacterial communities were found at 30-60 cm depths of mine tailings. Abundance and activity analysis of nifH genes also explained the elevated soil nitrogen contents at the surface 0-20 cm of the vegetated soils. These results suggest that microbial succession occurred primarily at surface tailings and vegetation of pioneering plants might have promoted ecological restoration of mine tailings.

  10. Ecological restoration alters microbial communities in mine tailings profiles.

    PubMed

    Li, Yang; Jia, Zhongjun; Sun, Qingye; Zhan, Jing; Yang, Yang; Wang, Dan

    2016-04-29

    Ecological restoration of mine tailings have impact on soil physiochemical properties and microbial communities. The surface soil has been a primary concern in the past decades, however it remains poorly understood about the adaptive response of microbial communities along the profile during ecological restoration of the tailings. In this study, microbial communities along a 60-cm profile were investigated in a mine tailing pond during ecological restoration of the bare waste tailings (BW) with two vegetated soils of Imperata cylindrica (IC) and Chrysopogon zizanioides (CZ) plants. Revegetation of both IC and CZ could retard soil degradation of mine tailing by stimulation of soil pH at 0-30 cm soils and altered the bacterial communities at 0-20 cm depths of the mine tailings. Significant differences existed in the relative abundance of the phyla Alphaproteobacteria, Deltaproteobacteria, Acidobacteria, Firmicutes and Nitrospira. Slight difference of bacterial communities were found at 30-60 cm depths of mine tailings. Abundance and activity analysis of nifH genes also explained the elevated soil nitrogen contents at the surface 0-20 cm of the vegetated soils. These results suggest that microbial succession occurred primarily at surface tailings and vegetation of pioneering plants might have promoted ecological restoration of mine tailings.

  11. Ecological restoration alters microbial communities in mine tailings profiles

    PubMed Central

    Li, Yang; Jia, Zhongjun; Sun, Qingye; Zhan, Jing; Yang, Yang; Wang, Dan

    2016-01-01

    Ecological restoration of mine tailings have impact on soil physiochemical properties and microbial communities. The surface soil has been a primary concern in the past decades, however it remains poorly understood about the adaptive response of microbial communities along the profile during ecological restoration of the tailings. In this study, microbial communities along a 60-cm profile were investigated in a mine tailing pond during ecological restoration of the bare waste tailings (BW) with two vegetated soils of Imperata cylindrica (IC) and Chrysopogon zizanioides (CZ) plants. Revegetation of both IC and CZ could retard soil degradation of mine tailing by stimulation of soil pH at 0–30 cm soils and altered the bacterial communities at 0–20 cm depths of the mine tailings. Significant differences existed in the relative abundance of the phyla Alphaproteobacteria, Deltaproteobacteria, Acidobacteria, Firmicutes and Nitrospira. Slight difference of bacterial communities were found at 30–60 cm depths of mine tailings. Abundance and activity analysis of nifH genes also explained the elevated soil nitrogen contents at the surface 0–20 cm of the vegetated soils. These results suggest that microbial succession occurred primarily at surface tailings and vegetation of pioneering plants might have promoted ecological restoration of mine tailings. PMID:27126064

  12. A proactive approach to sustainable management of mine tailings

    NASA Astrophysics Data System (ADS)

    Edraki, Mansour; Baumgartl, Thomas

    2015-04-01

    The reactive strategies to manage mine tailings i.e. containment of slurries of tailings in tailings storage facilities (TSF's) and remediation of tailings solids or tailings seepage water after the decommissioning of those facilities, can be technically inefficient to eliminate environmental risks (e.g. prevent dispersion of contaminants and catastrophic dam wall failures), pose a long term economic burden for companies, governments and society after mine closure, and often fail to meet community expectations. Most preventive environmental management practices promote proactive integrated approaches to waste management whereby the source of environmental issues are identified to help make a more informed decisions. They often use life cycle assessment to find the "hot spots" of environmental burdens. This kind of approach is often based on generic data and has rarely been used for tailings. Besides, life cycle assessments are less useful for designing operations or simulating changes in the process and consequent environmental outcomes. It is evident that an integrated approach for tailings research linked to better processing options is needed. A literature review revealed that there are only few examples of integrated approaches. The aim of this project is to develop new tailings management models by streamlining orebody characterization, process optimization and rehabilitation. The approach is based on continuous fingerprinting of geochemical processes from orebody to tailings storage facility, and benchmark the success of such proactive initiatives by evidence of no impacts and no future projected impacts on receiving environments. We present an approach for developing such a framework and preliminary results from a case study where combined grinding and flotation models developed using geometallurgical data from the orebody were constructed to predict the properties of tailings produced under various processing scenarios. The modelling scenarios based on the

  13. 14 CFR 23.481 - Tail down landing conditions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Tail down landing conditions. 23.481 Section 23.481 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... Ground Loads § 23.481 Tail down landing conditions. (a) For a tail down landing, the airplane is assumed...

  14. Structure-activity relationship studies of the lipophilic tail region of sphingosine kinase 2 inhibitors.

    PubMed

    Congdon, Molly D; Childress, Elizabeth S; Patwardhan, Neeraj N; Gumkowski, James; Morris, Emily A; Kharel, Yugesh; Lynch, Kevin R; Santos, Webster L

    2015-11-01

    Sphingosine-1-phosphate (S1P) is a ubiquitous, endogenous small molecule that is synthesized by two isoforms of sphingosine kinase (SphK1 and 2). Intervention of the S1P signaling pathway has attracted significant attention because alteration of S1P levels is linked to several disease states including cancer, fibrosis, and sickle cell disease. While intense investigations have focused on developing SphK1 inhibitors, only a limited number of SphK2-selective agents have been reported. Herein, we report our investigations on the structure-activity relationship studies of the lipophilic tail region of SLR080811, a SphK2-selective inhibitor. Our studies demonstrate that the internal phenyl ring is a key structural feature that is essential in the SLR080811 scaffold. Further, we show the dependence of SphK2 activity and selectivity on alkyl tail length, suggesting a larger lipid binding pocket in SphK2 compared to SphK1. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Moth tails divert bat attack: evolution of acoustic deflection.

    PubMed

    Barber, Jesse R; Leavell, Brian C; Keener, Adam L; Breinholt, Jesse W; Chadwell, Brad A; McClure, Christopher J W; Hill, Geena M; Kawahara, Akito Y

    2015-03-03

    Adaptations to divert the attacks of visually guided predators have evolved repeatedly in animals. Using high-speed infrared videography, we show that luna moths (Actias luna) generate an acoustic diversion with spinning hindwing tails to deflect echolocating bat attacks away from their body and toward these nonessential appendages. We pit luna moths against big brown bats (Eptesicus fuscus) and demonstrate a survival advantage of ∼ 47% for moths with tails versus those that had their tails removed. The benefit of hindwing tails is equivalent to the advantage conferred to moths by bat-detecting ears. Moth tails lured bat attacks to these wing regions during 55% of interactions between bats and intact luna moths. We analyzed flight kinematics of moths with and without hindwing tails and suggest that tails have a minimal role in flight performance. Using a robust phylogeny, we find that long spatulate tails have independently evolved four times in saturniid moths, further supporting the selective advantage of this anti-bat strategy. Diversionary tactics are perhaps more common than appreciated in predator-prey interactions. Our finding suggests that focusing on the sensory ecologies of key predators will reveal such countermeasures in prey.

  16. What a wish to die can mean: reasons, meanings and functions of wishes to die, reported from 30 qualitative case studies of terminally ill cancer patients in palliative care

    PubMed Central

    2014-01-01

    Background Despite research efforts over recent decades to deepen our understanding of why some terminally ill patients express a wish to die (WTD), there is broad consensus that we need more detailed knowledge about the factors that might influence such a wish. The objective of this study is to explore the different possible motivations and explanations of patients who express or experience a WTD. Methods Thirty terminally ill cancer patients, their caregivers and relatives; from a hospice, a palliative care ward in the oncology department of a general hospital, and an ambulatory palliative care service; 116 semi-structured qualitative interviews analysed using a complementary grounded theory and interpretive phenomenological analysis approach. Results Three dimensions were found to be crucial for understanding and analysing WTD statements: intentions, motivations and social interactions. This article analyses the motivations of WTD statements. Motivations can further be differentiated into (1) reasons, (2) meanings and (3) functions. Reasons are the factors that patients understand as causing them to have or accounting for having a WTD. These reasons can be ordered along the bio-psycho-socio-spiritual model. Meanings describe the broader explanatory frameworks, which explain what this wish means to a patient. Meanings are larger narratives that reflect personal values and moral understandings and cannot be reduced to reasons. Functions describe the effects of the WTD on patients themselves or on others, conscious or unconscious, that might be part of the motivation for a WTD. Nine typical ‘meanings’ were identified in the study, including “to let death put an end to severe suffering”, “to move on to another reality”, and – more frequently– “to spare others from the burden of oneself”. Conclusions The distinction between reasons, meanings and functions allows for a more detailed understanding of the motivation for the WTD statements of cancer

  17. Flexible histone tails in a new mesoscopic oligonucleosome model.

    PubMed

    Arya, Gaurav; Zhang, Qing; Schlick, Tamar

    2006-07-01

    We describe a new mesoscopic model of oligonucleosomes that incorporates flexible histone tails. The nucleosome cores are modeled using the discrete surface-charge optimization model, which treats the nucleosome as an electrostatic surface represented by hundreds of point charges; the linker DNAs are treated using a discrete elastic chain model; and the histone tails are modeled using a bead/chain hydrodynamic approach as chains of connected beads where each bead represents five protein residues. Appropriate charges and force fields are assigned to each histone chain so as to reproduce the electrostatic potential, structure, and dynamics of the corresponding atomistic histone tails at different salt conditions. The dynamics of resulting oligonucleosomes at different sizes and varying salt concentrations are simulated by Brownian dynamics with complete hydrodynamic interactions. The analyses demonstrate that the new mesoscopic model reproduces experimental results better than its predecessors, which modeled histone tails as rigid entities. In particular, our model with flexible histone tails: correctly accounts for salt-dependent conformational changes in the histone tails; yields the experimentally obtained values of histone-tail mediated core/core attraction energies; and considers the partial shielding of electrostatic repulsion between DNA linkers as a result of the spatial distribution of histone tails. These effects are crucial for regulating chromatin structure but are absent or improperly treated in models with rigid histone tails. The development of this model of oligonucleosomes thus opens new avenues for studying the role of histone tails and their variants in mediating gene expression through modulation of chromatin structure.

  18. Microbiota of little penguins and short-tailed shearwaters during development

    PubMed Central

    Arnould, John P. Y.; Allnutt, Theo R.; Crowley, Tamsyn; Krause, Lutz; Reynolds, John; Dann, Peter; Smith, Stuart C.

    2017-01-01

    The establishment and early colonisation of the gastrointestinal (GI) tract has been recognised as a crucial stage in chick development, with pioneering microbial species responsible for influencing the development of the GI tract and influencing host health, fitness and disease status throughout life. Development of the microbiota in long lived seabirds is poorly understood. This study characterised the microbial composition of little penguin and short-tailed shearwater chicks throughout development, using Quantitative Real Time PCR (qPCR) and 16S rRNA sequencing. The results indicated that microbial development differed between the two seabird species with the short-tailed shearwater microbiota being relatively stable throughout development whilst significant fluctuations in the microbial composition and an upward trend in the abundance of Firmicutes and Bacteroidetes were observed in the little penguin. When the microbial composition of adults and chicks was compared, both species showed low similarity in microbial composition, indicating that the adult microbiota may have a negligible influence over the chick’s microbiota. PMID:28806408

  19. From dinosaurs to birds: a tail of evolution

    PubMed Central

    2014-01-01

    A particularly critical event in avian evolution was the transition from long- to short-tailed birds. Primitive bird tails underwent significant alteration, most notably reduction of the number of caudal vertebrae and fusion of the distal caudal vertebrae into an ossified pygostyle. These changes, among others, occurred over a very short evolutionary interval, which brings into focus the underlying mechanisms behind those changes. Despite the wealth of studies delving into avian evolution, virtually nothing is understood about the genetic and developmental events responsible for the emergence of short, fused tails. In this review, we summarize the current understanding of the signaling pathways and morphological events that contribute to tail extension and termination and examine how mutations affecting the genes that control these pathways might influence the evolution of the avian tail. To generate a list of candidate genes that may have been modulated in the transition to short-tailed birds, we analyzed a comprehensive set of mouse mutants. Interestingly, a prevalent pleiotropic effect of mutations that cause fused caudal vertebral bodies (as in the pygostyles of birds) is tail truncation. We identified 23 mutations in this class, and these were primarily restricted to genes involved in axial extension. At least half of the mutations that cause short, fused tails lie in the Notch/Wnt pathway of somite boundary formation or differentiation, leading to changes in somite number or size. Several of the mutations also cause additional bone fusions in the trunk skeleton, reminiscent of those observed in primitive and modern birds. All of our findings were correlated to the fossil record. An open question is whether the relatively sudden appearance of short-tailed birds in the fossil record could be accounted for, at least in part, by the pleiotropic effects generated by a relatively small number of mutational events. PMID:25621146

  20. Induction of PrPSc-specific systemic and mucosal immune responses in white-tailed deer with an oral vaccine for chronic wasting disease

    PubMed Central

    Scruten, Erin; Woodbury, Murray; Potter, Andrew; Griebel, Philip; Tikoo, Suresh K.; Napper, Scott

    2017-01-01

    ABSTRACT The ongoing epidemic of chronic wasting disease (CWD) within cervid populations indicates the need for novel approaches for disease management. A vaccine that either reduces susceptibility to infection or reduces shedding of prions by infected animals, or a combination of both, could be of benefit for disease control. The development of such a vaccine is challenged by the unique nature of prion diseases and the requirement for formulation and delivery in an oral format for application in wildlife settings. To address the unique nature of prions, our group targets epitopes, termed disease specific epitopes (DSEs), whose exposure for antibody binding depends on disease-associated misfolding of PrPC into PrPSc. Here, a DSE corresponding to the rigid loop (RL) region, which was immunogenic following parenteral vaccination, was translated into an oral vaccine. This vaccine consists of a replication-incompetent human adenovirus expressing a truncated rabies glycoprotein G recombinant fusion with the RL epitope (hAd5:tgG-RL). Oral immunization of white-tailed deer with hAd5:tgG-RL induced PrPSc-specific systemic and mucosal antibody responses with an encouraging safety profile in terms of no adverse health effects nor prolonged vector shedding. By building upon proven strategies of formulation for wildlife vaccines, these efforts generate a particular PrPSc-specific oral vaccine for CWD as well as providing a versatile platform, in terms of carrier protein and biological vector, for generation of other oral, peptide-based CWD vaccines. PMID:28968152

  1. Unconventional tail configurations for transport aircraft

    NASA Astrophysics Data System (ADS)

    Sánchez-Carmona, A.; Cuerno-Rejado, C.; García-Hernández, L.

    2017-06-01

    This article presents the bases of a methodology in order to size unconventional tail configurations for transport aircraft. The case study of this paper is a V-tail con¦guration. Firstly, an aerodynamic study is developed for determining stability derivatives and aerodynamic forces. The objective is to size a tail such as it develops at least the same static stability derivatives than a conventional reference aircraft. The optimum is obtained minimizing its weight. The weight is estimated through two methods: adapted Farrar£s method and a statistical method. The solution reached is heavier than the reference, but it reduces the wetted area.

  2. Exploring Stellar Populations in the Tidal Tails of NGC3256

    NASA Astrophysics Data System (ADS)

    Rodruck, Michael; Konstantopoulos, Iraklis; Charlton, Jane C.

    2015-01-01

    Galaxy interactions can inject material into the intergalactic medium via violent gravitational dynamics, often visualized in tidal tails. The composition of these tails has remained a mystery, as previous studies have focused on detecting tidal features, rather than the composite material itself. With this in mind, we have developed an observing program using deep, multiband imaging to probe the chaotic regions of tidal tails in search for an underlying stellar population. NGC3256's Western and Eastern tidal tails serve as a case study for this new technique. Our results show median color values of u - g = 1.12 and r - i = 0.09 for the Western tail, and u - g = 1.29 and r - i = 0.21 for the Eastern tail, corresponding to ages of approximately 450 Myr and 900 Myr for the tails, respectively. A u - g color gradient is seen in the Western tail as well, running from 1.32 to 1.08 (~2000 Myr to 400 Myr), suggesting ages inside tidal tails can have significant variations.

  3. Sirenomelia apus with vestigial tail.

    PubMed

    Parikh, Tushar B; Nanavati, Ruchi N; Udani, Rekha H

    2005-04-01

    Sirenomelia is an exceptionally rare congenital malformation characterized by complete or near complete fusion of lower limbs. A newborn with clinical features of sirenomelia including fused lower limbs in medial position, absent fibula, anal atresia, complete absence of urogenital system (bilateral renal agenesis, absent ureters, urinary bladder, absent internal and external genitalia), a single umbilical artery and a vestigial tail is reported. Association of vestigial tail with sirenomelia is not described in the literature.

  4. BIOMECHANICS. Why the seahorse tail is square.

    PubMed

    Porter, Michael M; Adriaens, Dominique; Hatton, Ross L; Meyers, Marc A; McKittrick, Joanna

    2015-07-03

    Whereas the predominant shapes of most animal tails are cylindrical, seahorse tails are square prisms. Seahorses use their tails as flexible grasping appendages, in spite of a rigid bony armor that fully encases their bodies. We explore the mechanics of two three-dimensional-printed models that mimic either the natural (square prism) or hypothetical (cylindrical) architecture of a seahorse tail to uncover whether or not the square geometry provides any functional advantages. Our results show that the square prism is more resilient when crushed and provides a mechanism for preserving articulatory organization upon extensive bending and twisting, as compared with its cylindrical counterpart. Thus, the square architecture is better than the circular one in the context of two integrated functions: grasping ability and crushing resistance. Copyright © 2015, American Association for the Advancement of Science.

  5. A cross-sectional study for predicting tail biting risk in pig farms using classification and regression tree analysis.

    PubMed

    Scollo, Annalisa; Gottardo, Flaviana; Contiero, Barbara; Edwards, Sandra A

    2017-10-01

    Tail biting in pigs has been an identified behavioural, welfare and economic problem for decades, and requires appropriate but sometimes difficult on-farm interventions. The aim of the paper is to introduce the Classification and Regression Tree (CRT) methodologies to develop a tool for prevention of acute tail biting lesions in pigs on-farm. A sample of 60 commercial farms rearing heavy pigs were involved; an on-farm visit and an interview with the farmer collected data on general management, herd health, disease prevention, climate control, feeding and production traits. Results suggest a value for the CRT analysis in managing the risk factors behind tail biting on a farm-specific level, showing 86.7% sensitivity for the Classification Tree and a correlation of 0.7 between observed and predicted prevalence of tail biting obtained with the Regression Tree. CRT analysis showed five main variables (stocking density, ammonia levels, number of pigs per stockman, type of floor and timeliness in feed supply) as critical predictors of acute tail biting lesions, which demonstrate different importance in different farms subgroups. The model might have reliable and practical applications for the support and implementation of tail biting prevention interventions, especially in case of subgroups of pigs with higher risk, helping farmers and veterinarians to assess the risk in their own farm and to manage their predisposing variables in order to reduce acute tail biting lesions. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Metals in obex and retropharyngeal lymph nodes of Illinois white-tailed deer and their variations associated with CWD status.

    PubMed

    Rivera, Nelda A; Novakofski, Jan; Weng, Hsin-Yi; Kelly, Amy; Satterthwaite-Phillips, Damian; Ruiz, Marilyn O; Mateus-Pinilla, Nohra

    2015-01-01

    Prion proteins (PrP(C)) are cell membrane glycoproteins that can be found in many cell types, but specially in neurons. Many studies have suggested PrP(C)'s participation in metal transport and cellular protection against stress in the central nervous system (CNS). On the other hand PrP(Sc), the misfolded isoform of PrP(C) and the pathogenic agent in transmissible spongiform encephalopathies (TSE), has been associated with brain metal dyshomeostasis in prion diseases. Thus, changes in metal concentration associated with protein misfolding and aggregation have been reported for human and animal prion diseases, as well as for other neurodegenerative disorders, such as Parkinson's and Alzheimer's disease. The use of metal concentrations in tissues as surrogate markers for early detection of TSEs has been suggested. Studies on the accumulation of metals in free-ranging white-tailed deer have not been conducted. This study established concentrations of copper, iron, manganese, and magnesium in 2 diagnostic tissues used for CWD testing (obex and retropharyngeal lymph nodes (RLN)). We compared these concentrations between tissues and in relation to CWD status. We established reference intervals (RIs) for these metals and explored their ability to discriminate between CWD-positive and CWD-negative animals. Our results indicate that independent of CWD status, white-tailed deer accumulate higher concentrations of Fe, Mn and Mg in RLN than in obex. White-tailed deer infected with CWD accumulated significantly lower concentrations of Mn and Fe than CWD-negative deer. These patterns differed from other species infected with prion diseases. Overlapping values between CWD positive and negative groups indicate that evaluation of these metals in obex and RLN may not be appropriate as a diagnostic tool for CWD infection in white-tailed deer. Because the CWD-negative deer were included in constructing the RIs, high specificities were expected and should be interpreted with caution

  7. Experiments on a Tail-wheel Shimmy

    NASA Technical Reports Server (NTRS)

    Harling, R; Dietz, O

    1954-01-01

    Model tests on the "running belt" and tests with a full-scale tail wheel were made on a rotating drum as well as on a runway in order to investigate the causes of the undesirable shimmy phenomena frequently occurring on airplane tail wheels, and the means of avoiding them. The small model (scale 1:10) permitted simulation of the mass, moments of inertia, and fuselage stiffness of the airplane and determination of their influence on the shimmy, whereas by means of the larger model with pneumatic tires (scale 1:2) more accurate investigations were made on the tail wheel itself. The results of drum and road tests show good agreement with one another and with model values. Detailed investigations were made regarding the dependence of the shimmy tendency on trail, rolling speed, load, size of tires, ground friction,and inclination of the swivel axis; furthermore, regarding the influence of devices with restoring effect on the tail wheel, and the friction damping required for prevention of shimmy. Finally observations from slow-motion pictures are reported and conclusions drawn concerning the influence of tire deformation.

  8. Tail loss and thermoregulation in the common lizard Zootoca vivipara

    NASA Astrophysics Data System (ADS)

    Herczeg, Gábor; Kovács, Tibor; Tóth, Tamás; Török, János; Korsós, Zoltán; Merilä, Juha

    2004-10-01

    Tail autotomy in lizards is an adaptive strategy that has evolved to reduce the risk of predation. Since tail loss reduces body mass and moving ability—which in turn are expected to influence thermal balance—there is potential for a trade-off between tail autotomy and thermoregulation. To test this hypothesis, we studied a common lizard (Zootoca vivipara) population at high latitude, inhabiting a high-cost thermal environment. Z. vivipara is a small, non-territorial lizard known as a very accurate thermoregulator. We made two predictions: (1) the reduced body weight due to tail loss results in faster heating rate (a benefit), and (2) the reduction in locomotor ability after tail loss induces a shift to the use of thermally poorer microhabitats (a cost), thus decreasing the field body temperatures of active lizards. We did not find any effect of tail loss on heating rate in laboratory experiments conducted under different thermal conditions. Likewise, no significant relationship between tail condition and field body temperatures, or between tail condition and thermal microhabitat use, were detected. Thus, our results suggest that tail autotomy does not influence the accuracy of thermoregulation in small-bodied lizards.

  9. Tail loss and thermoregulation in the common lizard Zootoca vivipara.

    PubMed

    Herczeg, Gábor; Kovács, Tibor; Tóth, Tamás; Török, János; Korsós, Zoltán; Merilä, Juha

    2004-10-01

    Tail autotomy in lizards is an adaptive strategy that has evolved to reduce the risk of predation. Since tail loss reduces body mass and moving ability-which in turn are expected to influence thermal balance-there is potential for a trade-off between tail autotomy and thermoregulation. To test this hypothesis, we studied a common lizard (Zootoca vivipara) population at high latitude, inhabiting a high-cost thermal environment. Z. vivipara is a small, non-territorial lizard known as a very accurate thermoregulator. We made two predictions: (1) the reduced body weight due to tail loss results in faster heating rate (a benefit), and (2) the reduction in locomotor ability after tail loss induces a shift to the use of thermally poorer microhabitats (a cost), thus decreasing the field body temperatures of active lizards. We did not find any effect of tail loss on heating rate in laboratory experiments conducted under different thermal conditions. Likewise, no significant relationship between tail condition and field body temperatures, or between tail condition and thermal microhabitat use, were detected. Thus, our results suggest that tail autotomy does not influence the accuracy of thermoregulation in small-bodied lizards.

  10. On the folding phenomenon of comet tail rays

    NASA Astrophysics Data System (ADS)

    Ershkovich, A. I.

    1982-01-01

    It is shown that the folding phenomenon of the comet tail rays is compatible with the Ferraro isorotation law if the comet tail magnetic field has no azimuthal component, that is, Bphi (the polar angle) equals zero. Considering electric drift due to convectional electric fields, a formula is obtained for the angular rate of a ray closure which reduces to that of Ness and Donn (1966) if the velocity profile across the tail is linear. The magnetic field B of approximately 20-40 gammas in the coma and less than about 10 gammas in the distant tail is estimated under typical solar wind conditions at 1 AU.

  11. A note on trans-Planckian tail effects

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Graef, L.L.; Brandenberger, R., E-mail: leilagraef@usp.br, E-mail: rhb@physics.mcgill.ca

    2015-09-01

    We study the proposal by Mersini et al. [1] that the observed dark energy might be explained by the back-reaction of the set of tail modes in a theory with a dispersion relation in which the mode frequency decays exponentially in the trans-Planckian regime. The matter tail modes are frozen out, however they induce metric fluctuations. The energy-momentum tensor with which the tail modes effect the background geometry obtains contributions from both metric and matter fluctuations. We calculate the equation of state induced by the tail modes taking into account the gravitational contribution. We find that, in contrast to themore » case of frozen super-Hubble cosmological fluctuations, in this case the matter perturbations dominate, and they yield an equation of state which to leading order takes the form of a positive cosmological constant.« less

  12. Tail mean and related robust solution concepts

    NASA Astrophysics Data System (ADS)

    Ogryczak, Włodzimierz

    2014-01-01

    Robust optimisation might be viewed as a multicriteria optimisation problem where objectives correspond to the scenarios although their probabilities are unknown or imprecise. The simplest robust solution concept represents a conservative approach focused on the worst-case scenario results optimisation. A softer concept allows one to optimise the tail mean thus combining performances under multiple worst scenarios. We show that while considering robust models allowing the probabilities to vary only within given intervals, the tail mean represents the robust solution for only upper bounded probabilities. For any arbitrary intervals of probabilities the corresponding robust solution may be expressed by the optimisation of appropriately combined mean and tail mean criteria thus remaining easily implementable with auxiliary linear inequalities. Moreover, we use the tail mean concept to develope linear programming implementable robust solution concepts related to risk averse optimisation criteria.

  13. Adaptive Suction and Blowing for Twin-Tail Buffet Control

    NASA Technical Reports Server (NTRS)

    Kandil, Osama A.; Yang, Zhi

    1999-01-01

    Adaptive active flow control for twin-tail buffet alleviation is investigated. The concept behind this technique is to place control ports on the tail outer and inner surfaces with flow suction or blowing applied through these ports in order to minimize the pressure difference across the tail. The suction or blowing volume flow rate from each port is proportional to the pressure difference across the tail at this location. A parametric study of the effects of the number and location of these ports on the buffet response is carried out. The computational model consists of a sharp-edged delta wing of aspect ratio one and swept-back flexible twin tail with taper ratio of 0.23. This complex multidisciplinary problem is solved sequentially using three sets of equations for the fluid flow, aeroelastic response and grid deformation, using a dynamic multi-block grid structure. The computational model is pitched at 30 deg angle of attack. The freestream Mach number and Reynolds number are 0.3 and 1.25 million, respectively. The model is investigated for the inboard position of the twin tails, which corresponds to a separation distance between the twin tails of 33% of the wing span. Comparison of the time history and power spectral density responses of the tails for various distributions of the control ports are presented and discussed.

  14. Structural Conservation of the Myoviridae Phage Tail Sheath Protein Fold

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aksyuk, Anastasia A.; Kurochkina, Lidia P.; Fokine, Andrei

    2012-02-21

    Bacteriophage phiKZ is a giant phage that infects Pseudomonas aeruginosa, a human pathogen. The phiKZ virion consists of a 1450 {angstrom} diameter icosahedral head and a 2000 {angstrom}-long contractile tail. The structure of the whole virus was previously reported, showing that its tail organization in the extended state is similar to the well-studied Myovirus bacteriophage T4 tail. The crystal structure of a tail sheath protein fragment of phiKZ was determined to 2.4 {angstrom} resolution. Furthermore, crystal structures of two prophage tail sheath proteins were determined to 1.9 and 3.3 {angstrom} resolution. Despite low sequence identity between these proteins, all ofmore » these structures have a similar fold. The crystal structure of the phiKZ tail sheath protein has been fitted into cryo-electron-microscopy reconstructions of the extended tail sheath and of a polysheath. The structural rearrangement of the phiKZ tail sheath contraction was found to be similar to that of phage T4.« less

  15. Development in helicopter tail boom strake applications in the US

    NASA Technical Reports Server (NTRS)

    Wilson, John C.; Kelley, Henry L.; Donahue, Cynthia C.; Yenni, Kenneth R.

    1988-01-01

    The use of a strake or spoiler on a helicopter tail boom to beneficially change helicopter tail boom air loads was suggested in the United States in 1975. The anticipated benefits were a change of tail boom loads to reduce required tail rotor thrust and power and improve directional control. High tail boom air loads experienced by the YAH-64 and described in 1978 led to a wind tunnel investigation of the usefullness of strakes in altering such loads on the AH-64, UH-60, and UH-1 helicopters. The wind tunnel tests of 2-D cross sections of the tail boom of each demonstrated that a strake or strakes would be effective. Several limited test programs with the U.S. Army's OH-58A, AH-64, and UH-60A were conducted which showed the effects of strakes were modest for those helicopters. The most recent flight test program, with a Bell 204B, disclosed that for the 204B the tail boom strake or strakes would provide more than a modest improvement in directional control and reduction in tail rotor power.

  16. Downtown People Mover (DPM) Winterization Test Demonstration : Westinghouse

    DOT National Transportation Integrated Search

    1982-01-01

    The Westinghouse Downtown People Mover (DPM) Winterization Test Demonstration (WTD) Final Report covers the 1978-79 and 1979-80 winter periods. Tests were performed at the Westinghouse Transportation Division (WTD) test track located in Pittsburgh, P...

  17. Reduced West Nile Virus Transmission Around Communal Roosts of Great-Tailed Grackle (Quiscalus mexicanus).

    PubMed

    Komar, Nicholas; Colborn, James M; Horiuchi, Kalanthe; Delorey, Mark; Biggerstaff, Brad; Damian, Dan; Smith, Kirk; Townsend, John

    2015-03-01

    West Nile virus has caused several outbreaks among humans in the Phoenix metropolitan area (Arizona, southwest USA) within the last decade. Recent ecologic studies have implicated Culex quinquefasciatus and Culex tarsalis as the mosquito vectors and identified three abundant passerine birds-great-tailed grackle (Quiscalus mexicanus), house sparrow (Passer domesticus), and house finch (Haemorhous mexicanus)-as key amplifiers among vertebrates. Nocturnal congregations of certain species have been suggested as critical for late summer West Nile virus amplification. We evaluated the hypothesis that house sparrow (P. domesticus) and/or great-tailed grackle (Q. mexicanus) communal roost sites (n = 22 and n = 5, respectively) in a primarily suburban environment were spatially associated with West Nile virus transmission indices during the 2010 outbreak of human neurological disease in metropolitan Phoenix. Spatial associations between human case residences and communal roosts were non-significant for house sparrows, and were negative for great-tailed grackle. Several theories that explain these observations are discussed, including the possibility that grackle communal roosts are protective.

  18. Reduced West Nile Virus Transmission Around Communal Roosts of Great-Tailed Grackle (Quiscalus mexicanus)

    PubMed Central

    Komar, Nicholas; Colborn, James M.; Horiuchi, Kalanthe; Delorey, Mark; Biggerstaff, Brad; Damian, Dan; Smith, Kirk; Townsend, John

    2016-01-01

    West Nile virus has caused several outbreaks among humans in the Phoenix metropolitan area (Arizona, southwest USA) within the last decade. Recent ecologic studies have implicated Culex quinquefasciatus and Culex tarsalis as the mosquito vectors and identified three abundant passerine birds—great-tailed grackle (Quiscalus mexicanus), house sparrow (Passer domesticus), and house finch (Haemorhous mexicanus)—as key amplifiers among vertebrates. Nocturnal congregations of certain species have been suggested as critical for late summer West Nile virus amplification. We evaluated the hypothesis that house sparrow (P. domesticus) and/or great-tailed grackle (Q. mexicanus) communal roost sites (n = 22 and n = 5, respectively) in a primarily suburban environment were spatially associated with West Nile virus transmission indices during the 2010 outbreak of human neurological disease in metropolitan Phoenix. Spatial associations between human case residences and communal roosts were non-significant for house sparrows, and were negative for great-tailed grackle. Several theories that explain these observations are discussed, including the possibility that grackle communal roosts are protective. PMID:25480320

  19. A note on trans-Planckian tail effects

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Graef, L.L.; Instituto de Física, Universidade de São Paulo, Rua do Matão travessa R, São Paulo, SP, 05508-090; Brandenberger, R.

    2015-09-09

    We study the proposal by Mersini et al. http://dx.doi.org/10.1103/PhysRevD.64.043508 that the observed dark energy might be explained by the back-reaction of the set of tail modes in a theory with a dispersion relation in which the mode frequency decays exponentially in the trans-Planckian regime. The matter tail modes are frozen out, however they induce metric fluctuations. The energy-momentum tensor with which the tail modes effect the background geometry obtains contributions from both metric and matter fluctuations. We calculate the equation of state induced by the tail modes taking into account the gravitational contribution. We find that, in contrast to themore » case of frozen super-Hubble cosmological fluctuations, in this case the matter perturbations dominate, and they yield an equation of state which to leading order takes the form of a positive cosmological constant.« less

  20. Indirect Solar Wind Measurements Using Archival Cometary Tail Observations

    NASA Astrophysics Data System (ADS)

    Zolotova, Nadezhda; Sizonenko, Yuriy; Vokhmyanin, Mikhail; Veselovsky, Igor

    2018-05-01

    This paper addresses the problem of the solar wind behaviour during the Maunder minimum. Records on plasma tails of comets can shed light on the physical parameters of the solar wind in the past. We analyse descriptions and drawings of comets between the eleventh and eighteenth century. To distinguish between dust and plasma tails, we address their colour, shape, and orientation. Based on the calculations made by F.A. Bredikhin, we found that cometary tails deviate from the antisolar direction on average by more than 10°, which is typical for dust tails. We also examined the catalogues of Hevelius and Lubieniecki. The first indication of a plasma tail was revealed only for the great comet C/1769 P1.

  1. 14 CFR 23.497 - Supplementary conditions for tail wheels.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Structure Ground Loads § 23.497 Supplementary conditions for tail wheels. In determining the ground loads on the tail wheel and affected supporting structures, the following apply: (a) For the obstruction load, the limit ground reaction obtained in the tail down landing condition is assumed to act up and aft...

  2. 14 CFR 23.497 - Supplementary conditions for tail wheels.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Structure Ground Loads § 23.497 Supplementary conditions for tail wheels. In determining the ground loads on the tail wheel and affected supporting structures, the following apply: (a) For the obstruction load, the limit ground reaction obtained in the tail down landing condition is assumed to act up and aft...

  3. 14 CFR 29.411 - Ground clearance: tail rotor guard.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Ground clearance: tail rotor guard. 29.411 Section 29.411 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... System Loads § 29.411 Ground clearance: tail rotor guard. (a) It must be impossible for the tail rotor to...

  4. 14 CFR 27.411 - Ground clearance: tail rotor guard.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Ground clearance: tail rotor guard. 27.411 Section 27.411 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... System Loads § 27.411 Ground clearance: tail rotor guard. (a) It must be impossible for the tail rotor to...

  5. 14 CFR 27.411 - Ground clearance: tail rotor guard.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Ground clearance: tail rotor guard. 27.411 Section 27.411 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... System Loads § 27.411 Ground clearance: tail rotor guard. (a) It must be impossible for the tail rotor to...

  6. 14 CFR 29.411 - Ground clearance: tail rotor guard.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Ground clearance: tail rotor guard. 29.411 Section 29.411 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... System Loads § 29.411 Ground clearance: tail rotor guard. (a) It must be impossible for the tail rotor to...

  7. Thresher sharks use tail-slaps as a hunting strategy.

    PubMed

    Oliver, Simon P; Turner, John R; Gann, Klemens; Silvosa, Medel; D'Urban Jackson, Tim

    2013-01-01

    The hunting strategies of pelagic thresher sharks (Alopias pelagicus) were investigated at Pescador Island in the Philippines. It has long been suspected that thresher sharks hunt with their scythe-like tails but the kinematics associated with the behaviour in the wild are poorly understood. From 61 observations recorded by handheld underwater video camera between June and October 2010, 25 thresher shark shunting events were analysed. Thresher sharks employed tail-slaps to debilitate sardines at all times of day. Hunting events comprised preparation, strike, wind-down recovery and prey item collection phases, which occurred sequentially. Preparation phases were significantly longer than the others, presumably to enable a shark to windup a tail-slap. Tail-slaps were initiated by an adduction of the pectoral fins, a manoeuvre that changed a thresher shark's pitch promoting its posterior region to lift rapidly, and stall its approach. Tail-slaps occurred with such force that they may have caused dissolved gas to diffuse out of the water column forming bubbles. Thresher sharks were able to consume more than one sardine at a time, suggesting that tail-slapping is an effective foraging strategy for hunting schooling prey. Pelagic thresher sharks appear to pursue sardines opportunistically by day and night, which may make them vulnerable to fisheries. Alopiids possess specialist pectoral and caudal fins that are likely to have evolved, at least in part, for tail-slapping. The evidence is now clear; thresher sharks really do hunt with their tails.

  8. Thresher Sharks Use Tail-Slaps as a Hunting Strategy

    PubMed Central

    Oliver, Simon P.; Turner, John R.; Gann, Klemens; Silvosa, Medel; D'Urban Jackson, Tim

    2013-01-01

    The hunting strategies of pelagic thresher sharks (Alopias pelagicus) were investigated at Pescador Island in the Philippines. It has long been suspected that thresher sharks hunt with their scythe-like tails but the kinematics associated with the behaviour in the wild are poorly understood. From 61 observations recorded by handheld underwater video camera between June and October 2010, 25 thresher shark shunting events were analysed. Thresher sharks employed tail-slaps to debilitate sardines at all times of day. Hunting events comprised preparation, strike, wind-down recovery and prey item collection phases, which occurred sequentially. Preparation phases were significantly longer than the others, presumably to enable a shark to windup a tail-slap. Tail-slaps were initiated by an adduction of the pectoral fins, a manoeuvre that changed a thresher shark's pitch promoting its posterior region to lift rapidly, and stall its approach. Tail-slaps occurred with such force that they may have caused dissolved gas to diffuse out of the water column forming bubbles. Thresher sharks were able to consume more than one sardine at a time, suggesting that tail-slapping is an effective foraging strategy for hunting schooling prey. Pelagic thresher sharks appear to pursue sardines opportunistically by day and night, which may make them vulnerable to fisheries. Alopiids possess specialist pectoral and caudal fins that are likely to have evolved, at least in part, for tail-slapping. The evidence is now clear; thresher sharks really do hunt with their tails. PMID:23874415

  9. Novel full-length major histocompatibility complex class I allele discovery and haplotype definition in pig-tailed macaques.

    PubMed

    Semler, Matthew R; Wiseman, Roger W; Karl, Julie A; Graham, Michael E; Gieger, Samantha M; O'Connor, David H

    2018-06-01

    Pig-tailed macaques (Macaca nemestrina, Mane) are important models for human immunodeficiency virus (HIV) studies. Their infectability with minimally modified HIV makes them a uniquely valuable animal model to mimic human infection with HIV and progression to acquired immunodeficiency syndrome (AIDS). However, variation in the pig-tailed macaque major histocompatibility complex (MHC) and the impact of individual transcripts on the pathogenesis of HIV and other infectious diseases is understudied compared to that of rhesus and cynomolgus macaques. In this study, we used Pacific Biosciences single-molecule real-time circular consensus sequencing to describe full-length MHC class I (MHC-I) transcripts for 194 pig-tailed macaques from three breeding centers. We then used the full-length sequences to infer Mane-A and Mane-B haplotypes containing groups of MHC-I transcripts that co-segregate due to physical linkage. In total, we characterized full-length open reading frames (ORFs) for 313 Mane-A, Mane-B, and Mane-I sequences that defined 86 Mane-A and 106 Mane-B MHC-I haplotypes. Pacific Biosciences technology allows us to resolve these Mane-A and Mane-B haplotypes to the level of synonymous allelic variants. The newly defined haplotypes and transcript sequences containing full-length ORFs provide an important resource for infectious disease researchers as certain MHC haplotypes have been shown to provide exceptional control of simian immunodeficiency virus (SIV) replication and prevention of AIDS-like disease in nonhuman primates. The increased allelic resolution provided by Pacific Biosciences sequencing also benefits transplant research by allowing researchers to more specifically match haplotypes between donors and recipients to the level of nonsynonymous allelic variation, thus reducing the risk of graft-versus-host disease.

  10. A Tale of Two Tails: Not Just Skin Deep

    PubMed Central

    Dutta, Abhijit; Ghosh, Sudip Kumar; Mandal, Asok Kumar

    2015-01-01

    The dorsal cutaneous appendage or the so called human tail is a rare congenital anomaly protruding from the lumbo-sacro-coccygeal area. These caudal appendages are divided into true-tails and pseudo-tails. We report here two cases of congenital pseudo-tail with underlying spina bifida and lipo-meningocele. In this article we seek to emphasize that, as the skin and nervous systems are intimately linked by their similar ectodermal origin, a dorsal appendage may be regarded as a cutaneous marker of the underlying spinal dysraphism. PMID:26288414

  11. A potential role for bat tail membranes in flight control.

    PubMed

    Gardiner, James D; Dimitriadis, Grigorios; Codd, Jonathan R; Nudds, Robert L

    2011-03-30

    Wind tunnel tests conducted on a model based on the long-eared bat Plecotus auritus indicated that the positioning of the tail membrane (uropatagium) can significantly influence flight control. Adjusting tail position by increasing the angle of the legs ventrally relative to the body has a two-fold effect; increasing leg-induced wing camber (i.e., locally increased camber of the inner wing surface) and increasing the angle of attack of the tail membrane. We also used our model to examine the effects of flying with and without a tail membrane. For the bat model with a tail membrane increasing leg angle increased the lift, drag and pitching moment (nose-down) produced. However, removing the tail membrane significantly reduced the change in pitching moment with increasing leg angle, but it had no significant effect on the level of lift produced. The drag on the model also significantly increased with the removal of the tail membrane. The tail membrane, therefore, is potentially important for controlling the level of pitching moment produced by bats and an aid to flight control, specifically improving agility and manoeuvrability. Although the tail of bats is different from that of birds, in that it is only divided from the wings by the legs, it nonetheless, may, in addition to its prey capturing function, fulfil a similar role in aiding flight control.

  12. A Potential Role for Bat Tail Membranes in Flight Control

    PubMed Central

    Gardiner, James D.; Dimitriadis, Grigorios; Codd, Jonathan R.; Nudds, Robert L.

    2011-01-01

    Wind tunnel tests conducted on a model based on the long-eared bat Plecotus auritus indicated that the positioning of the tail membrane (uropatagium) can significantly influence flight control. Adjusting tail position by increasing the angle of the legs ventrally relative to the body has a two-fold effect; increasing leg-induced wing camber (i.e., locally increased camber of the inner wing surface) and increasing the angle of attack of the tail membrane. We also used our model to examine the effects of flying with and without a tail membrane. For the bat model with a tail membrane increasing leg angle increased the lift, drag and pitching moment (nose-down) produced. However, removing the tail membrane significantly reduced the change in pitching moment with increasing leg angle, but it had no significant effect on the level of lift produced. The drag on the model also significantly increased with the removal of the tail membrane. The tail membrane, therefore, is potentially important for controlling the level of pitching moment produced by bats and an aid to flight control, specifically improving agility and manoeuvrability. Although the tail of bats is different from that of birds, in that it is only divided from the wings by the legs, it nonetheless, may, in addition to its prey capturing function, fulfil a similar role in aiding flight control. PMID:21479137

  13. Mycobacteriosis in a black-tailed deer (Odocoileus hemionus columbianus) caused by Mycobacterium kansasii

    USGS Publications Warehouse

    Hall, P.B.; Bender, L.C.; Garner, M.M.

    2005-01-01

    An eviscerated hunter-harvested female black-tailed deer (Odocoileus hemionus columbianus) was submitted to the Washington Department of Fish and Wildlife. The deer was emaciated, devoid of adipose tissue, and the parietal surface of the thoracic cavity contained multiple granulomas. Acid-fast bacteria were detected histologically from the granulomas and were isolated and identified as Mycobacterium kansasii, a nontuberculous mycobacterium sporadically reported to cause tuberculosis-like disease in a variety of vertebrates. This was the first report of symptomatic disease caused by M. kansasii in free-ranging deer. This case indicates that atypical mycobacteria can cause tuberculosis-like disease in free-ranging deer and illustrates the importance of identifying causative agents of tuberculosis-like disease in wildlife. Copyright 2005 by American Association of Zoo Veterinarians.

  14. Vertical Tail Buffeting Alleviation Using Piezoelectric Actuators: Some Results of the Actively Controlled Response of Buffet-Affected Tails (ACROBAT) Program

    NASA Technical Reports Server (NTRS)

    Moses, Robert W.

    1997-01-01

    A 1/6-scale F-18 wind-tunnel model was tested in the Transonic Dynamics Tunnel at the NASA Langley Research Center as part of the Actively Controlled Response Of Buffet Affected Tails (ACROBAT) program to assess the use of active controls in reducing vertical tail buffeting. The starboard vertical tail was equipped with an active rudder and the port vertical tail was equipped with piezoelectric actuators. The tunnel conditions were atmospheric air at a dynamic pressure of 14 psf. By using single-input-single-output control laws at gains well below the physical limits of the actuators, the power spectral density of the root strains at the frequency of the first bending mode of the vertical tail was reduced by as much as 60 percent up to angles of attack of 37 degrees. Root mean square (RMS) values of root strain were reduced by as much as 19 percent. Buffeting alleviation results when using the rudder are presented for comparison. Stability margins indicate that a constant gain setting in the control law may be used throughout the range of angle of attack tested.

  15. Preliminary study on evaluation of the pancreatic tail observable limit of transabdominal ultrasonography using a position sensor and CT-fusion image.

    PubMed

    Sumi, Hajime; Itoh, Akihiro; Kawashima, Hiroki; Ohno, Eizaburo; Itoh, Yuya; Nakamura, Yosuke; Hiramatsu, Takeshi; Sugimoto, Hiroyuki; Hayashi, Daijuro; Kuwahara, Takamichi; Morishima, Tomomasa; Kawai, Manabu; Furukawa, Kazuhiro; Funasaka, Kohei; Nakamura, Masanao; Miyahara, Ryoji; Katano, Yoshiaki; Ishigami, Masatoshi; Ohmiya, Naoki; Goto, Hidemi; Hirooka, Yoshiki

    2014-08-01

    Transabdominal ultrasonography (US) is commonly used for the initial screening of bilio-pancreatic diseases in Asian countries due to its widespread availability, the non-invasiveness and the cost-effectiveness. However, it is considered that US has limits to observe the area, namely the blind area. The observation of the pancreatic tail is particularly difficult. The goal of this study was to examine the pancreatic tail region that cannot be visualized on transverse scanning of the upper abdomen using US with spatial positional information and factors related to visualization, and observation of the tail from the splenic hilum. Thirty-nine patients with pancreatic/biliary tract disease underwent CT and US with GPS-like technology and fusion imaging for measurement of the real pancreatic length and the predicted/real unobservable (PU and RU) length of the pancreatic tail. RU from US on transverse scanning and the real pancreatic length were used to determine the unobservable area (UA: RU/the real pancreatic length). Relationships of RU with physical and hematological variables that might influence visualization of the pancreatic tail were investigated. The real pancreatic length was 160.9 ± 16.4mm, RU was 41.0 ± 17.8mm, and UA was 25.3 ± 10.4%. RU was correlated with BMI (R=0.446, P=0.004) and waist circumferences (R=0.354, P=0.027), and strongly correlated with PU (R=0.788, P<0.001). The pancreatic tail was visible from the splenic hilum in 22 (56%) subjects and was completely identified in 13 (33%) subjects. Combined GPS-like technology with fusion imaging was useful for the objective estimation of the pancreatic blind area. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  16. Radon emanation from backfilled mill tailings in underground uranium mine.

    PubMed

    Sahu, Patitapaban; Mishra, Devi Prasad; Panigrahi, Durga Charan; Jha, Vivekananda; Patnaik, R Lokeswara; Sethy, Narendra Kumar

    2014-04-01

    Coarser mill tailings used as backfill to stabilize the stoped out areas in underground uranium mines is a potential source of radon contamination. This paper presents the quantitative assessment of radon emanation from the backfilled tailings in Jaduguda mine, India using a cylindrical accumulator. Some of the important parameters such as (226)Ra activity concentration, bulk density, bulk porosity, moisture content and radon emanation factor of the tailings affecting radon emanation were determined in the laboratory. The study revealed that the radon emanation rate of the tailings varied in the range of 0.12-7.03 Bq m(-2) s(-1) with geometric mean of 1.01 Bq m(-2) s(-1) and geometric standard deviation of 3.39. An increase in radon emanation rate was noticed up to a moisture saturation of 0.09 in the tailings, after which the emanation rate gradually started declining with saturation due to low diffusion coefficient of radon in the saturated tailings. Radon emanation factor of the tailings varied in the range of 0.08-0.23 with the mean value of 0.21. The emanation factor of the tailings with moisture saturation level over 0.09 was found to be about three times higher than that of the absolutely dry tailings. The empirical relationship obtained between (222)Rn emanation rate and (226)Ra activity concentration of the tailings indicated a significant positive linear correlation (r = 0.95, p < 0.001). This relationship may be useful for quick prediction of radon emanation rate from the backfill material of similar nature. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Effect of Configuration Pitching Motion on Twin Tail Buffet Response

    NASA Technical Reports Server (NTRS)

    Sheta, Essam F.; Kandil, Osama A.

    1998-01-01

    The effect of dynamic pitch-up motion of delta wing on twin-tail buffet response is investigated. The computational model consists of a delta wing-twin tail configuration. The computations are carried out on a dynamic multi-block grid structure. This multidisciplinary problem is solved using three sets of equations which consists of the unsteady Navier-Stokes equations, the aeroelastic equations, and the grid displacement equations. The configuration is pitched-up from zero up to 60 deg. angle of attack, and the freestream Mach number and Reynolds number are 0.3 and 1.25 million, respectively. With the twin tail fixed as rigid surfaces and with no-forced pitch-up motion, the problem is solved for the initial flow conditions. Next, the problem is solved for the twin-tail response for uncoupled bending and torsional vibrations due to the unsteady loads on the twin tail and due to the forced pitch-up motion. The dynamic pitch-up problem is also solved for the flow response with the twin tail kept rigid. The configuration is investigated for inboard position of the twin tail which corresponds to a separation distance between the twin tail of 33% wing chord. The computed results are compared with the available experimental data.

  18. Tail regeneration affects the digestive performance of a Mediterranean lizard

    NASA Astrophysics Data System (ADS)

    Sagonas, Kostas; Karambotsi, Niki; Bletsa, Aristoula; Reppa, Aikaterini; Pafilis, Panayiotis; Valakos, Efstratios D.

    2017-04-01

    In caudal autotomy, lizards shed their tail to escape from an attacking predator. Since the tail serves multiple functions, caudal regeneration is of pivotal importance. However, it is a demanding procedure that requires substantial energy and nutrients. Therefore, lizards have to increase energy income to fuel the extraordinary requirements of the regenerating tail. We presumed that autotomized lizards would adjust their digestion to acquire this additional energy. To clarify the effects of tail regeneration on digestion, we compared the digestive performance before autotomy, during regeneration, and after its completion. Tail regeneration indeed increased gut passage time but did not affect digestive performance in a uniform pattern: though protein income was maximized, lipid and sugar acquisition remained stable. This divergence in proteins may be attributed to their particular role in tail reconstruction, as they are the main building blocks for tissue formation.

  19. Orphan Stars Found in Long Galaxy Tail

    NASA Astrophysics Data System (ADS)

    2007-09-01

    Astronomers have found evidence that stars have been forming in a long tail of gas that extends well outside its parent galaxy. This discovery suggests that such "orphan" stars may be much more prevalent than previously thought. The comet-like tail was observed in X-ray light with NASA's Chandra X-ray Observatory and in optical light with the Southern Astrophysical Research (SOAR) telescope in Chile. The feature extends for more than 200,000 light years and was created as gas was stripped from a galaxy called ESO 137-001 that is plunging toward the center of Abell 3627, a giant cluster of galaxies. "This is one of the longest tails like this we have ever seen," said Ming Sun of Michigan State University, who led the study. "And, it turns out that this is a giant wake of creation, not of destruction." Chandra X-ray Image of ESO 137-001 and Tail in Abell 3627 Chandra X-ray Image of ESO 137-001 and Tail in Abell 3627 The observations indicate that the gas in the tail has formed millions of stars. Because the large amounts of gas and dust needed to form stars are typically found only within galaxies, astronomers have previously thought it unlikely that large numbers of stars would form outside a galaxy. "This isn't the first time that stars have been seen to form between galaxies," said team member Megan Donahue, also of MSU. "But the number of stars forming here is unprecedented." The evidence for star formation in this tail includes 29 regions of ionized hydrogen glowing in optical light, thought to be from newly formed stars. These regions are all downstream of the galaxy, located in or near the tail. Two Chandra X-ray sources are near these regions, another indication of star formation activity. The researchers believe the orphan stars formed within the last 10 million years or so. The stars in the tail of this fast-moving galaxy, which is some 220 million light years away, would be much more isolated than the vast majority of stars in galaxies. H-alpha Image of

  20. Cell lineage tracing during Xenopus tail regeneration.

    PubMed

    Gargioli, Cesare; Slack, Jonathan M W

    2004-06-01

    The tail of the Xenopus tadpole will regenerate following amputation, and all three of the main axial structures - the spinal cord, the notochord and the segmented myotomes - are found in the regenerated tail. We have investigated the cellular origin of each of these three tissue types during regeneration. We produced Xenopus laevis embryos transgenic for the CMV (Simian Cytomegalovirus) promoter driving GFP (Green Fluorescent Protein) ubiquitously throughout the embryo. Single tissues were then specifically labelled by making grafts at the neurula stage from transgenic donors to unlabelled hosts. When the hosts have developed to tadpoles, they carry a region of the appropriate tissue labelled with GFP. These tails were amputated through the labelled region and the distribution of labelled cells in the regenerate was followed. We also labelled myofibres using the Cre-lox method. The results show that the spinal cord and the notochord regenerate from the same tissue type in the stump, with no labelling of other tissues. In the case of the muscle, we show that the myofibres of the regenerate arise from satellite cells and not from the pre-existing myofibres. This shows that metaplasia between differentiated cell types does not occur, and that the process of Xenopus tail regeneration is more akin to tissue renewal in mammals than to urodele tail regeneration.

  1. Predicting arsenic concentrations in porewaters of buried uranium mill tailings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Langmuir, D.; Mahoney, J.; MacDonald, A.

    The proposed JEB Tailings Management Facility (TMF) to be emplaced below the groundwater table in northern Saskatchewan, Canada, will contain uranium mill tailings from McClean Lake, Midwest and Cigar Lake ore bodies, which are high in arsenic (up to 10%) and nickel (up to 5%). A serious concern is the possibility that high arsenic and nickel concentrations may be released from the buried tailings, contaminating adjacent groundwaters and a nearby lake. Laboratory tests and geochemical modeling were performed to examine ways to reduce the arsenic and nickel concentrations in TMF porewaters so as to minimize such contamination from tailings buriedmore » for 50 years and longer. The tests were designed to mimic conditions in the mill neutralization circuit (3 hr tests at 25 C), and in the TMF after burial (5--49 day aging tests). The aging tests were run at 50, 25 and 4 C (the temperature in the TMF). In order to optimize the removal of arsenic by adsorption and precipitation, ferric sulfate was added to tailings raffinates having Fe/As ratios of less than 3--5. The acid raffinates were then neutralized by addition of slaked lime to nominal pH values of 7, 8, or 9. Analysis and modeling of the test results showed that with slaked lime addition to acid tailings raffinates, relatively amorphous scorodite (ferric arsenate) precipitates near pH 1, and is the dominant form of arsenate in slake limed tailings solids except those high in Ni and As and low in Fe, in which cabrerite-annabergite (Ni, Mg, Fe(II) arsenate) may also precipitate near pH 5--6. In addition to the arsenate precipitates, smaller amounts of arsenate are also adsorbed onto tailings solids. The aging tests showed that after burial of the tailings, arsenic concentrations may increase with time from the breakdown of the arsenate phases (chiefly scorodite). However, the tests indicate that the rate of change decreases and approaches zero after 72 hrs at 25 C, and may equal zero at all times in the TMF at 4

  2. PSR J0357+3205: THE TAIL OF THE TURTLE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marelli, M.; De Luca, A.; Salvetti, D.

    2013-03-01

    Using a new XMM-Newton observation, we have characterized the X-ray properties of the middle-aged radio-quiet {gamma}-ray pulsar J0357+3205 (named Morla) and its tail. The X-ray emission from the pulsar is consistent with a magnetospheric non-thermal origin plus a thermal emission from a hot spot (or hot spots). The lack of a thermal component from the whole surface makes Morla the coldest neutron star in its age range. We found marginal evidence for a double-peaked modulation of the X-ray emission. The study of the 9' long tail confirmed the lack of extended emission near the pulsar itself. The tail shows amore » very asymmetric brightness profile and its spectrum lacks any spatial variation. We found the nebular emission to be inconsistent with a classical bow shock, ram-pressure-dominated pulsar wind nebula. We propose thermal bremsstrahlung as an alternative mechanism for Morla's tail emission. In this scenario, the tail emission comes from the shocked interstellar medium (ISM) material heated up to X-ray temperatures. This can fully explain the peculiar features of the tail, assuming a hot, moderately dense ISM around the pulsar. For a bremsstrahlung-emitting tail, we can estimate the pulsar distance to be between 300 and 900 pc. A pulsar velocity of {approx}1900 km s{sup -1} is required, which would make Morla the pulsar with the largest velocity, and high inclination angles (>70 Degree-Sign ) are preferred. We propose Morla's nebula as the first example of a new 'turtle's tail' class of thermally emitting nebulae associated with high-velocity pulsars.« less

  3. The tails of the satellite auroral footprints at Jupiter

    NASA Astrophysics Data System (ADS)

    Bonfond, B.; Saur, J.; Grodent, D.; Badman, S. V.; Bisikalo, D.; Shematovich, V.; Gérard, J.-C.; Radioti, A.

    2017-08-01

    The electromagnetic interaction between Io, Europa, and Ganymede and the rotating plasma that surrounds Jupiter has a signature in the aurora of the planet. This signature, called the satellite footprint, takes the form of a series of spots located slightly downstream of the feet of the field lines passing through the moon under consideration. In the case of Io, these spots are also followed by an extended tail in the downstream direction relative to the plasma flow encountering the moon. A few examples of a tail for the Europa footprint have also been reported in the northern hemisphere. Here we present a simplified Alfvénic model for footprint tails and simulations of vertical brightness profiles for various electron distributions, which favor such a model over quasi-static models. We also report here additional cases of Europa footprint tails, in both hemispheres, even though such detections are rare and difficult. Furthermore, we show that the Ganymede footprint can also be followed by a similar tail. Finally, we present a case of a 320° long Io footprint tail, while other cases in similar configurations do not display such a length.

  4. Hydrodynamic Characteristics of a Low-drag, Planing-tail Flying-boat Hull

    NASA Technical Reports Server (NTRS)

    Suydam, Henry B

    1948-01-01

    The hydrodynamic characteristics of a flying-boat incorporating a low-drag, planing-tail hull were determined from model tests made in Langley tank number 2 and compared with tests of the same flying boat incorporating a conventional-type hull. The planing-tail model, with which stable take-offs were possible for a large range of elevator positions at all center-of-gravity locations tested, had more take-off stability than the conventional model. No upper-limit porpoising was encountered by the planing-tail model. The maximum changes in rise during landings were lower for the planing-tail model than for the conventional model at most contact trims, an indication of improved landing stability for the planing-tail model. The hydrodynamic resistance of the planing-tail hull was lower than the conventional hull at all speeds, and the load-resistance ratio was higher for the planing-tail hull, being especially high at the hump. The static trim of the planing-tail hull was much higher than the conventional hull, but the variation of trim with speed during take-off was smaller.

  5. Heavy-tailed fractional Pearson diffusions.

    PubMed

    Leonenko, N N; Papić, I; Sikorskii, A; Šuvak, N

    2017-11-01

    We define heavy-tailed fractional reciprocal gamma and Fisher-Snedecor diffusions by a non-Markovian time change in the corresponding Pearson diffusions. Pearson diffusions are governed by the backward Kolmogorov equations with space-varying polynomial coefficients and are widely used in applications. The corresponding fractional reciprocal gamma and Fisher-Snedecor diffusions are governed by the fractional backward Kolmogorov equations and have heavy-tailed marginal distributions in the steady state. We derive the explicit expressions for the transition densities of the fractional reciprocal gamma and Fisher-Snedecor diffusions and strong solutions of the associated Cauchy problems for the fractional backward Kolmogorov equation.

  6. Hydrogen-bond rich ionic liquids with hydroxyl cationic tails

    NASA Astrophysics Data System (ADS)

    Deng, Li; Shi, Rui; Wang, Yanting; Ou-Yang, Zhong-Can

    2013-02-01

    To investigate if the amphiphilic feature exhibited in ionic liquids (ILs) with nonpolar cationic tails still exists in ILs with polar tails, by performing molecular dynamics simulations for 1-(8-hydroxyoctyl)-3-methyl-imidazolium nitrate (COH) and 1-octyl-3-methyl-imidazolium nitrate (C8), we found that, in COH, cationic tail groups can no longer aggregate to form separated nonpolar tail domains, instead hydroxyl groups form a rich number of hydrogen bonds with other groups, indicating that the hydroxyl substituent changes the IL system from an amphiphilic liquid to a polar liquid. Due to the large amount of hydrogen bonds, COH has slower dynamics than C8.

  7. Linking bovine tuberculosis on cattle farms to white-tailed deer and environmental variables using Bayesian hierarchical analysis

    USGS Publications Warehouse

    Walter, W. David; Smith, Rick; Vanderklok, Mike; VerCauterren, Kurt C.

    2014-01-01

    Bovine tuberculosis is a bacterial disease caused by Mycobacterium bovis in livestock and wildlife with hosts that include Eurasian badgers (Meles meles), brushtail possum (Trichosurus vulpecula), and white-tailed deer (Odocoileus virginianus). Risk-assessment efforts in Michigan have been initiated on farms to minimize interactions of cattle with wildlife hosts but research onM. bovis on cattle farms has not investigated the spatial context of disease epidemiology. To incorporate spatially explicit data, initial likelihood of infection probabilities for cattle farms tested for M. bovis, prevalence of M. bovis in white-tailed deer, deer density, and environmental variables for each farm were modeled in a Bayesian hierarchical framework. We used geo-referenced locations of 762 cattle farms that have been tested for M. bovis, white-tailed deer prevalence, and several environmental variables that may lead to long-term survival and viability of M. bovis on farms and surrounding habitats (i.e., soil type, habitat type). Bayesian hierarchical analyses identified deer prevalence and proportion of sandy soil within our sampling grid as the most supported model. Analysis of cattle farms tested for M. bovisidentified that for every 1% increase in sandy soil resulted in an increase in odds of infection by 4%. Our analysis revealed that the influence of prevalence of M. bovis in white-tailed deer was still a concern even after considerable efforts to prevent cattle interactions with white-tailed deer through on-farm mitigation and reduction in the deer population. Cattle farms test positive for M. bovis annually in our study area suggesting that the potential for an environmental source either on farms or in the surrounding landscape may contributing to new or re-infections with M. bovis. Our research provides an initial assessment of potential environmental factors that could be incorporated into additional modeling efforts as more knowledge of deer herd

  8. Effectiveness of Flow Control for Alleviation of Twin-Tail Buffet

    NASA Technical Reports Server (NTRS)

    Sheta, Essam F.; Kandil, Osama A.; Yang, Zhi

    1998-01-01

    Effectiveness of active flow control for twin- tail buffet alleviation is investigated. Tangen- tial leading-edge blowing (TLEB) and flow suction along the vortex cores (FSVC) of the lead- ing edges of the delta wing are used to delay the vortex breakdown flow upstream of the twin tail. The combined effect of the TLEB and FSVC is also investigated. A parametric study of the effects of the spanwise position of the suction tubes and volumetric suction flow rate on the twin-tail buffet response are also investigated. The TLEB moves the path of leading-edge vortices laterally towards the twin tail, which increases the aero- dynamic damping on the tails. The FSVC effectively delays the breakdown location at high angles of attack. The computational model consists of a sharp-edged delta wing of aspect ratio one and swept-back flexible twin tail with taper ratio of 0.23. This complex multidisciplinary problem is solved sequentially using three sets of equations for the fluid flow, aeroelastic response and grid deformation, on a dynamic multi-block grid structure. The computational model is pitched at 30 deg. angle of attack. The freestream Mach number and Reynolds number are 0.3 and 1.25 million, respectively. The model is investigated for the inboard position of the twin tails, which corresponds to a separation distance between the twin tails of 33% of the wing span.

  9. Can tail damage outbreaks in the pig be predicted by behavioural change?

    PubMed

    Larsen, Mona Lilian Vestbjerg; Andersen, Heidi Mai-Lis; Pedersen, Lene Juul

    2016-03-01

    Tail biting, resulting in outbreaks of tail damage in pigs, is a multifactorial welfare and economic problem which is usually partly prevented through tail docking. According to European Union legislation, tail docking is not allowed on a routine basis; thus there is a need for alternative preventive methods. One strategy is the surveillance of the pigs' behaviour for known preceding indicators of tail damage, which makes it possible to predict a tail damage outbreak and prevent it in proper time. This review discusses the existing literature on behavioural changes observed prior to a tail damage outbreak. Behaviours found to change prior to an outbreak include increased activity level, increased performance of enrichment object manipulation, and a changed proportion of tail posture with more tails between the legs. Monitoring these types of behaviours is also discussed for the purpose of developing an automatic warning system for tail damage outbreaks, with activity level showing promising results for being monitored automatically. Encouraging results have been found so far for the development of an automatic warning system; however, there is a need for further investigation and development, starting with the description of the temporal development of the predictive behaviour in relation to tail damage outbreaks. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Curved tails in polymerization-based bacterial motility

    NASA Astrophysics Data System (ADS)

    Rutenberg, Andrew D.; Grant, Martin

    2001-08-01

    The curved actin ``comet-tail'' of the bacterium Listeria monocytogenes is a visually striking signature of actin polymerization-based motility. Similar actin tails are associated with Shigella flexneri, spotted-fever Rickettsiae, the Vaccinia virus, and vesicles and microspheres in related in vitro systems. We show that the torque required to produce the curvature in the tail can arise from randomly placed actin filaments pushing the bacterium or particle. We find that the curvature magnitude determines the number of actively pushing filaments, independent of viscosity and of the molecular details of force generation. The variation of the curvature with time can be used to infer the dynamics of actin filaments at the bacterial surface.

  11. Metallicity gradients in tidal tails and merging systems

    NASA Astrophysics Data System (ADS)

    Torres-Flores, S.; Scarano, S., Jr.; Olave, D.; Alfaro, M.; Mendes de Oliveira, C.; de Mello, D. F.; Carrasco, E. R.; Amram, P.; Plana, H.

    2014-10-01

    We present an analysis of the metal distribution in the tidal tails of two interacting systems and in the main body of a galaxy merger: NGC92, NGC6845 and HCG31, respectively. Using Gemini/GMOS spectroscopic data, we found no metallicity gradients for the tail of NGC92. The abundances in the tail are similar to the values displayed by the central regions of NGC92. This fact suggests that gas mixing triggered by the interaction produces a flattening in the metallicity distribution of this system. For the system NGC6845, we found that regions located in the tail have similar abundances to one source located in the inner region of this galaxy, also suggesting a flat metal distribution. For HCG 31 we found an inhomogeneous metal distribution for the central region. Apparently, each star forming complex keeps its metal abundance despite the strong gravitational interaction that this system suffered. In the case of the tidal tails, our results support the scenario in which gas mixing produces a flattening in the metal distribution. However, we suggest that the star formation is an important mechanism in enhancing the oxygen abundance of these structures.

  12. Mine tailings composition in a historic site: implications for ecological restoration.

    PubMed

    Courtney, R

    2013-02-01

    Ecological restoration, using tolerant plant species and nutrient additions, is a low-cost option to decrease environmental risks associated with mine tailings. An attempt was previously made to establish such a vegetation cover on an abandoned tailings facility in Southern Ireland. Historically, the tailings site has been prone to dusting and is a potential source of contamination to the surrounding environment. The site was examined to determine the success of the previous restoration plan used to revegetate the site and to determine its suitability for further restoration. Three distinct floristic areas were identified (grassland, poor grassland and bare area) based on herbage compositions and elemental analysis. Surface and subsurface samples were taken to characterise tailings from within these areas of the tailings site. The pH of bare surface tailings (pH, 2.7) was significantly more acidic (p < 0.5) than in other areas. Additionally, negligible net neutralising potential resulted in the tailings being hostile to plant growth. Total metal concentrations in tailings were high (c. 10,000 mg kg(-1) for Pb and up to 20,000 mg kg(-1) for Zn). DTPA-extractable Zn and Pb were 16 and 11 % of the total amount, respectively. Metal content in grasses growing on some areas of the tailings were elevated and demonstrated the inability of the tailings to support sustainable plant growth. Due to the inherently hostile characteristics of these areas, future restoration work will employ capping with a barrier layer.

  13. AGES OF STAR CLUSTERS IN THE TIDAL TAILS OF MERGING GALAXIES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mulia, A. J.; Chandar, R.; Whitmore, B. C.

    We study the stellar content in the tidal tails of three nearby merging galaxies, NGC 520, NGC 2623, and NGC 3256, using BVI imaging taken with the Advanced Camera for Surveys on board the Hubble Space Telescope. The tidal tails in all three systems contain compact and fairly massive young star clusters, embedded in a sea of diffuse, unresolved stellar light. We compare the measured colors and luminosities with predictions from population synthesis models to estimate cluster ages and find that clusters began forming in tidal tails during or shortly after the formation of the tails themselves. We find amore » lack of very young clusters (≤10 Myr old), implying that eventually star formation shuts off in the tails as the gas is used up or dispersed. There are a few clusters in each tail with estimated ages that are older than the modeled tails themselves, suggesting that these may have been stripped out from the original galaxy disks. The luminosity function of the tail clusters can be described by a single power-law, dN/dL ∝ L{sup α}, with −2.6 < α < −2.0. We find a stellar age gradient across some of the tidal tails, which we interpret as a superposition of (1) newly formed stars and clusters along the dense center of the tail and (2) a sea of broadly distributed, older stellar material ejected from the progenitor galaxies.« less

  14. Effects of plant growth-promoting bacteria isolated from copper tailings on plants in sterilized and non-sterilized tailings.

    PubMed

    Liu, Weiqiu; Yang, Chao; Shi, Si; Shu, Wensheng

    2014-02-01

    Ten strains of Cu-tolerant bacteria with potential plant growth-promoting ability were isolated by selecting strains with the ability to use 1-aminocyclopropane-1-carboxylate as a sole nitrogen source (designated ACC-B) or fix nitrogen (designated FLN-B) originating from the rhizosphere of plants growing on copper tailings. All 10 strains proved to have intrinsic ability to produce indole acetic acid and siderophores, and most of them could mobilize insoluble phosphate. In addition, a greenhouse study showed that ACC-B, FLN-B and a mixture of both had similar, potent ability to stimulate growth of Pennisetum purpureum, Medicago sativa and Oenothera erythrosepala plants grown on sterilized tailings. For instance, above-ground biomass of P. purpureum was 278-357% greater after 60d growth on sterilized tailings in their presence. They could also significantly promote the growth of the plants grown on non-sterilized tailings, though the growth-promoting effects were much weaker. So, strategies for using of the plant growth-promoting bacteria in the practice of phytoremediation deserve further studies to get higher growth-promoting efficiency. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. Coupled eco-hydrology and biogeochemistry algorithms enable the simulation of water table depth effects on boreal peatland net CO2 exchange

    NASA Astrophysics Data System (ADS)

    Mezbahuddin, Mohammad; Grant, Robert F.; Flanagan, Lawrence B.

    2017-12-01

    Water table depth (WTD) effects on net ecosystem CO2 exchange of boreal peatlands are largely mediated by hydrological effects on peat biogeochemistry and the ecophysiology of peatland vegetation. The lack of representation of these effects in carbon models currently limits our predictive capacity for changes in boreal peatland carbon deposits under potential future drier and warmer climates. We examined whether a process-level coupling of a prognostic WTD with (1) oxygen transport, which controls energy yields from microbial and root oxidation-reduction reactions, and (2) vascular and nonvascular plant water relations could explain mechanisms that control variations in net CO2 exchange of a boreal fen under contrasting WTD conditions, i.e., shallow vs. deep WTD. Such coupling of eco-hydrology and biogeochemistry algorithms in a process-based ecosystem model, ecosys, was tested against net ecosystem CO2 exchange measurements in a western Canadian boreal fen peatland over a period of drier-weather-driven gradual WTD drawdown. A May-October WTD drawdown of ˜ 0.25 m from 2004 to 2009 hastened oxygen transport to microbial and root surfaces, enabling greater microbial and root energy yields and peat and litter decomposition, which raised modeled ecosystem respiration (Re) by 0.26 µmol CO2 m-2 s-1 per 0.1 m of WTD drawdown. It also augmented nutrient mineralization, and hence root nutrient availability and uptake, which resulted in improved leaf nutrient (nitrogen) status that facilitated carboxylation and raised modeled vascular gross primary productivity (GPP) and plant growth. The increase in modeled vascular GPP exceeded declines in modeled nonvascular (moss) GPP due to greater shading from increased vascular plant growth and moss drying from near-surface peat desiccation, thereby causing a net increase in modeled growing season GPP by 0.39 µmol CO2 m-2 s-1 per 0.1 m of WTD drawdown. Similar increases in GPP and Re caused no significant WTD effects on modeled

  16. Modeling of Longitudinal Unsteady Aerodynamics of a Wing-Tail Combination

    NASA Technical Reports Server (NTRS)

    Klein, Vladislav

    1999-01-01

    Aerodynamic equations for the longitudinal motion of an aircraft with a horizontal tail were developed. In this development emphasis was given on obtaining model structure suitable for model identification from experimental data. The resulting aerodynamic models included unsteady effects in the form of linear indicial functions. These functions represented responses in the lift on the wing and tail alone, and interference between those two lifting surfaces. The effect of the wing on the tail was formulated for two different expressions concerning the downwash angle at the tail. The first expression used the Cowley-Glauert approximation known-as "lag-in-downwash," the second took into account growth of the wing circulation and delay in the development of the lift on the tail. Both approaches were demonstrated in two examples using the geometry of a fighter aircraft and a large transport. It was shown that the differences in the two downwash formulations would increase for an aircraft with long tail arm performing low-speed, rapid maneuvers.

  17. Managing 'tail liability'.

    PubMed

    Frese, Richard C; Weber, Ryan J

    2013-11-01

    To reduce and control their level of tail liability, hospitals should: Utilize a self-insurance vehicle; Consider combined limits between the hospital and physicians; Communicate any program changes to the actuary, underwriter, and auditor; Continue risk management and safety practices; Ensure credit is given to the organization's own medical malpractice program.

  18. Identification of chromosomal locations associated with tail biting and being a victim of tail-biting behaviour in the domestic pig (Sus scrofa domesticus).

    PubMed

    Wilson, Kaitlin; Zanella, Ricardo; Ventura, Carlos; Johansen, Hanne Lind; Framstad, Tore; Janczak, Andrew; Zanella, Adroaldo J; Neibergs, Holly Louise

    2012-11-01

    The objective of this study was to identify loci associated with tail biting or being a victim of tail biting in Norwegian crossbred pigs using a genome-wide association study with PLINK case-control analysis. DNA was extracted from hair or blood samples collected from 98 trios of crossbred pigs located across Norway. Each trio came from the same pen and consisted of one pig observed to initiate tail biting, one pig which was the victim of tail biting and a control pig which was not involved in either behaviour. DNA was genotyped using the Illumina PorcineSNP60 BeadChip whole-genome single-nucleotide polymorphism (SNP) assay. After quality assurance filtering, 53,952 SNPs remained comprising 74 animals (37 pairs) for the tail biter versus control comparison and 53,419 SNPs remained comprising 80 animals (40 pairs) for the victim of tail biting versus control comparison. An association with being a tail biter was observed on Sus scrofa chromosome 16 (SSC16; p = 1.6 × 10(-5)) and an unassigned chromosome (p = 3.9 × 10(-5)). An association with being the victim of tail biting was observed on Sus scrofa chromosomes 1 (SSC1; p = 4.7 × 10(-5)), 9 (SSC9; p = 3.9 × 10(-5)), 18 (SSC18; p = 7 × 10(-5) for 9,602,511 bp, p = 3.4 × 10(-5) for 9,653,881 bp and p = 5.3 × 10(-5) for 29,577,783 bp) and an unassigned chromosome (p = 6.1 × 10(-5)). An r(2) = 0.96 and a D' = 1 between the two SNPs at 9 Mb on SSC18 indicated extremely high linkage disequilibrium, suggesting that these two markers represent a single locus. These results provide evidence of a moderate genetic association between the propensity to participate in tail-biting behaviour and the likelihood of becoming a victim of this behaviour.

  19. A review on in situ phytoremediation of mine tailings.

    PubMed

    Wang, Li; Ji, Bin; Hu, Yuehua; Liu, Runqing; Sun, Wei

    2017-10-01

    Mine tailings are detrimental to natural plant growth due to their physicochemical characteristics, such as high pH, high salinity, low water retention capacity, high heavy metal concentrations, and deficiencies in soil organic matter and fertility. Thus, the remediation of mine tailings has become a key issue in environmental science and engineering. Phytoremediation, an in situ cost-effective technology, is emerging as the most promising remediation method for mine tailings by introducing tolerant plant species. It is particularly effective in dealing with large-area mine tailings with shallow contamination of organic, nutrient and metal pollutants. In this review, the background, concepts and applications of phytoremediation are comprehensively discussed. Furthermore, proper amendments used to improve the physical, chemical and biological properties of mine tailings are systematically reviewed and compared. Emphasis is placed on the types and characteristics of tolerant plants and their role in phytoremediation. Moreover, the role of microorganisms and their mechanism in phytoremediation are also discussed in-depth. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Rapid oxidation of sulfide mine tailings by reaction with potassium ferrate.

    PubMed

    Murshed, Mohamed; Rockstraw, David A; Hanson, Adrian T; Johnson, Michael

    2003-01-01

    The chemistry of sulfide mine tailings treated with potassium ferrate (K2FeO4) in aqueous slurry has been investigated. The reaction system is believed to parallel a geochemical oxidation in which ferrate ion replaces oxygen. This chemical system utilized in a pipeline (as a plug flow reactor) may have application eliminating the potential for tailings to leach acid while recovering the metal from the tailings. Elemental analyses were performed using an ICP spectrometer for the aqueous phase extract of the treated tailings; and an SEM-EDX for the tailing solids. Solids were analyzed before and after treatments were applied. ICP shows that as the mass ratio of ferrate ion to tailings increases, the concentration of metals in the extract solution increases; while EDX indicates a corresponding decrease in sulfur content of the tailing solids. The extraction of metal and reduction in sulfide content is significant. The kinetic timeframe is on the order of minutes.

  1. Spin-resolved electron waiting times in a quantum-dot spin valve

    NASA Astrophysics Data System (ADS)

    Tang, Gaomin; Xu, Fuming; Mi, Shuo; Wang, Jian

    2018-04-01

    We study the electronic waiting-time distributions (WTDs) in a noninteracting quantum-dot spin valve by varying spin polarization and the noncollinear angle between the magnetizations of the leads using the scattering matrix approach. Since the quantum-dot spin valve involves two channels (spin up and down) in both the incoming and outgoing channels, we study three different kinds of WTDs, which are two-channel WTD, spin-resolved single-channel WTD, and cross-channel WTD. We analyze the behaviors of WTDs in short times, correlated with the current behaviors for different spin polarizations and noncollinear angles. Cross-channel WTD reflects the correlation between two spin channels and can be used to characterize the spin-transfer torque process. We study the influence of the earlier detection on the subsequent detection from the perspective of cross-channel WTD, and define the influence degree quantity as the cumulative absolute difference between cross-channel WTDs and first-passage time distributions to quantitatively characterize the spin-flip process. We observe that influence degree versus spin-transfer torque for different noncollinear angles as well as different polarizations collapse into a single curve showing universal behaviors. This demonstrates that cross-channel WTDs can be a pathway to characterize spin correlation in spintronics system.

  2. Tailings dam-break flow - Analysis of sediment transport

    NASA Astrophysics Data System (ADS)

    Aleixo, Rui; Altinakar, Mustafa

    2015-04-01

    A common solution to store mining debris is to build tailings dams near the mining site. These dams are usually built with local materials such as mining debris and are more vulnerable than concrete dams (Rico et al. 2008). of The tailings and the pond water generally contain heavy metals and various toxic chemicals used in ore extraction. Thus, the release of tailings due to a dam-break can have severe ecological consequences in the environment. A tailings dam-break has many similarities with a common dam-break flow. It is highly transient and can be severely descructive. However, a significant difference is that the released sediment-water mixture will behave as a non-Newtonian flow. Existing numerical models used to simulate dam-break flows do not represent correctly the non-Newtonian behavior of tailings under a dam-break flow and may lead to unrealistic and incorrect results. The need for experiments to extract both qualitative and quantitative information regarding these flows is therefore real and actual. The present paper explores an existing experimental data base presented in Aleixo et al. (2014a,b) to further characterize the sediment transport under conditions of a severe transient flow and to extract quantitative information regarding sediment flow rate, sediment velocity, sediment-sediment interactions a among others. Different features of the flow are also described and analyzed in detail. The analysis is made by means of imaging techniques such as Particle Image Velocimetry and Particle Tracking Velocimetry that allow extracting not only the velocity field but the Lagrangian description of the sediments as well. An analysis of the results is presented and the limitations of the presented experimental approach are discussed. References Rico, M., Benito, G., Salgueiro, AR, Diez-Herrero, A. and Pereira, H.G. (2008) Reported tailings dam failures: A review of the European incidents in the worldwide context , Journal of Hazardous Materials, 152, 846

  3. A tail like no other. The RPC-MAG view of Rosetta's tail excursion at comet 67P/Churyumov-Gerasimenko

    NASA Astrophysics Data System (ADS)

    Volwerk, Martin; Goetz, Charlotte; Richter, Ingo; Delva, Magda; Ostaszewski, Katharina; Schwingenschuh, Konrad; Glassmeier, Karl-Heinz

    2018-06-01

    Context. The Rosetta Plasma Consortium (RPC) magnetometer (MAG) data during the tail excursion in March-April 2016 are used to investigate the magnetic structure of and activity in the tail region of the weakly outgassing comet 67P/Churyumov-Gerasimenko (67P). Aims: The goal of this study is to compare the large scale (near) tail structure with that of earlier missions to strong outgassing comets, and the small scale turbulent energy cascade (un)related to the singing comet phenomenon. Methods: The usual methods of space plasma physics are used to analyse the magnetometer data, such as minimum variance analysis, spectral analysis, and power law fitting. Also the cone angle and clock angle of the magnetic field are calculated to interpret the data. Results: It is found that comet 67P does not have a classical draped magnetic field and no bi-lobal tail structure at this late stage of the mission when the comet is already at 2.7 AU distance from the Sun. The main magnetic field direction seems to be more across the tail direction, which may implicate an asymmetric pick-up cloud. During periods of singing comet activity the propagation direction of the waves is at large angles with respect to the magnetic field and to the radial direction towards the comet. Turbulent cascade of magnetic energy from large to small scales is different in the presence of singing as without it.

  4. Remote control canard missile with a free-rolling tail brake torque system

    NASA Technical Reports Server (NTRS)

    Blair, A. B., Jr.

    1981-01-01

    An experimental wind-tunnel investigation has been conducted at supersonic Mach numbers to determine the static aerodynamic characteristics of a cruciform canard-controlled missile with fixed and free-rolling tail-fin afterbodies. Mechanical coupling effects of the free-rolling tail afterbody were investigated using an electronic/electromagnetic brake system that provides arbitrary tail-fin brake torques with continuous measurements of tail-to-mainframe torque and tail-roll rate. Results are summarized to show the effects of fixed and free-rolling tail-fin afterbodies that include simulated measured bearing friction torques on the longitudinal and lateral-directional aerodynamic characteristics.

  5. Hematologic Parameters and Viral Status for Zika, Chikungunya, Bluetongue, and Epizootic Hemorrhagic Disease in White-tailed Deer ( Odocoileus virginianus) on St John, US Virgin Islands.

    PubMed

    Reuter, Jon D; Nelson, Suzanne L

    2018-05-24

    A population of white-tailed deer ( Odocoileus virginianus) resides throughout the island of St John, US Virgin Islands, predominately in the Virgin Islands National Park. Adult deer ( n=23), ranging from 1 yr to 8 yr old, were assessed to characterize body condition and health. Serologic samples were screened for important viral pathogens in the area, including Zika, chikungunya, bluetongue, and epizootic hemorrhagic disease viruses. Samples were collected in July 2016; males were in velvet and all females were in diestrus. Deer had recovered from a severe drought the previous year but were generally healthy, with a low-level but high incidence of tick parasitism. Marked statistically significant changes in hematocrit and hemoglobin levels were associated with the effects of the anesthetic mixture used for capture. No other statistically significant differences were observed. Serum from four deer induced reduction in Zika virus plaques, suggesting possible exposure. No serum was reactive for chikungunya virus. Bluetongue and epizootic hemorrhagic disease antibodies were present in 50% of the sampled deer, but no clinical signs associated with disease were observed during the study period. These data will be valuable for future dynamic health assessment and may help assess changes to the population, such as those induced by climate change, infectious disease, or other demographic events.

  6. Recycling of asbestos tailings used as reinforcing fillers in polypropylene based composites.

    PubMed

    Zhai, Wensi; Wang, Yao; Deng, Yuan; Gao, Hongli; Lin, Zhen; Li, Mao

    2014-04-15

    In this work, asbestos tailings were recycled and used as reinforcing fillers to enhance the mechanical properties of polypropylene (PP). A silane coupling agent was used to chemically modify the asbestos tailings to increase the compatibility between asbestos tailings and polypropylene matrix. Both raw and chemically treated asbestos tailings with different loading levels (from 3 to 30 wt%) were utilized to fabricate composites. Mechanical properties of these composites have been investigated by dynamic mechanical analysis, tensile test and notched impact test. Results showed that hybridization of asbestos tailings in the composites enhanced the mechanical properties of neat PP evidently, and treated asbestos tailings/PP composites yielded even better mechanical properties compared with those of raw asbestos tailings/PP composites. This recycling method of asbestos tailings not only reduces disposal costs and avoids secondary pollution but also produces a new PP-based composite material with enhanced mechanical properties. Copyright © 2014 Elsevier B.V. All rights reserved.

  7. White-tailed deer

    Treesearch

    Paul E. Johns; John C. Kilgo

    2005-01-01

    from a public relations standpoint, the white-tailed deer (Odocileus virginiamus) is probably the most important wildlife species occurring on the Savannah River Site (SRS). The SRS deer herd has been the subject of more scientific investigations than any comparable deer population in the world, resulting in more than 125 published papers. Each year...

  8. Research investigation of helicopter main rotor/tail rotor interaction noise

    NASA Technical Reports Server (NTRS)

    Fitzgerald, J.; Kohlhepp, F.

    1988-01-01

    Acoustic measurements were obtained in a Langley 14 x 22 foot Subsonic Wind Tunnel to study the aeroacoustic interaction of 1/5th scale main rotor, tail rotor, and fuselage models. An extensive aeroacoustic data base was acquired for main rotor, tail rotor, fuselage aerodynamic interaction for moderate forward speed flight conditions. The details of the rotor models, experimental design and procedure, aerodynamic and acoustic data acquisition and reduction are presented. The model was initially operated in trim for selected fuselage angle of attack, main rotor tip-path-plane angle, and main rotor thrust combinations. The effects of repositioning the tail rotor in the main rotor wake and the corresponding tail rotor countertorque requirements were determined. Each rotor was subsequently tested in isolation at the thrust and angle of attack combinations for trim. The acoustic data indicated that the noise was primarily dominated by the main rotor, especially for moderate speed main rotor blade-vortex interaction conditions. The tail rotor noise increased when the main rotor was removed indicating that tail rotor inflow was improved with the main rotor present.

  9. Giant Metrewave Radio Telescope Observations of Head–Tail Radio Galaxies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sebastian, Biny; Lal, Dharam V.; Rao, A. Pramesh, E-mail: biny@ncra.tifr.res.in

    We present results from a study of seven large known head–tail radio galaxies based on observations using the Giant Metrewave Radio Telescope at 240 and 610 MHz. These observations are used to study the radio morphologies and distribution of the spectral indices across the sources. The overall morphology of the radio tails of these sources is suggestive of random motions of the optical host around the cluster potential. The presence of multiple bends and wiggles in several head–tail sources is possibly due to the precessing radio jets. We find steepening of the spectral index along the radio tails. The prevailingmore » equipartition magnetic field also decreases along the radio tails of these sources. These steepening trends are attributed to the synchrotron aging of plasma toward the ends of the tails. The dynamical ages of these sample sources have been estimated to be ∼10{sup 8} yr, which is a factor of six more than the age estimates from the radiative losses due to synchrotron cooling.« less

  10. Plasma currents and anisotropy in the tail-dipole transition region

    NASA Astrophysics Data System (ADS)

    Artemyev, A.; Zhang, X. J.; Angelopoulos, V.; Runov, A.

    2017-12-01

    Using conjugated THEMIS and Van Allen Probes observations in the nightside magnetosphere, we examine statistically plasma and magnetic field characteristics at multiple locations simultaneously across the 3-10 RE region (i.e., across the tail-dipole transition region, whose location depends on tail flux loading and the strength of global convection). We find that the spatial distributions of ion and electron anisotropies vary significantly but systematically with radial distance and geomagnetic activity. For low Kp (<2), ions are transversely anisotropic near Earth but isotropic in the tail, whereas electrons are isotropic closer to Earth but field-aligned in tail. For large Kp (>4), the anisotropy profiles for ions and electrons reverse: ions are isotropic closer to the Earth and field-aligned in the tail, whereas electrons are transversely anisotropic closer to Earth but isotropic in the tail. Using the measured plasma anisotropy radial profiles we estimate the currents from curvature drifts and compare them with diamagnetic currents. We also discuss the implications of the observed plasma anisotropies for the presence and spatial distribution of field-aligned electric fields.

  11. Use of cemented paste backfill in arsenic-rich tailings

    NASA Astrophysics Data System (ADS)

    Hamberg, Roger; Maurice, Christian; Alakangas, Lena

    2015-04-01

    Gold is extracted by cyanide leaching from inclusions in arsenopyrite from a mine in the north of Sweden. The major ore mineral assemblage consists of pyrrhotite and arsenopyrite-loellingite. Effluents from the gold extraction were treated with Fe2(SO4)3, with the aim to form stable As-bearing Fe-precipitates (FEP). The use of the method called cemented paste backfill (CPB) is sometimes suggested for the management of tailings. In CPB, tailings are commonly mixed with low proportions (3 - 7 %) of cement and backfilled into underground excavated area. To reduce costs, amendments such as granulated blast furnace slag (GBFS), biofuel fly ash (BFA) and cement kiln dust (CKD) are used for partial replacement of cement in CPB due to their pozzolanic and alkaline properties. The objective for this study was to evaluate the leaching behaviour of As in CPB-mixtures with low proportions (1 - 3 %) of BFA and ordinary cement and unmodified tailings. The selection of CPB-recipies was made based on technical and economical criterias to adress the demands deriving from the mining operations. Speciation of the As in ore and tailings samples revealed that mining processes have dissolved the majority of the arsenopyrite in the ore, causing secondary As phases to co-precipitate with newly formed FEP:s. Tank leaching tests (TLT) and weathering cells (WCT) were used to compare leaching behaviour in a monolithic mass contra a crushed material. Quantification of the presumed benefit of CPB was made by calculation of the cumulative leaching of As. Results from the leaching tests (TLT and WCT) showed that the inclusion of As-rich tailings into a cementitious matrix increased leaching of As. This behaviour could partially be explained by an increase of pH. The addition of alkaline binder materials to tailings increased As leaching due to the relocation of desorbed As from FEPs into less acid-tolerant species such as Ca-arsenates and cementitious As-phases. Unmodified tailings generated an

  12. Influence of World Thrombosis Day on digital information seeking on venous thrombosis: a Google Trends study.

    PubMed

    Scheres, L J J; Lijfering, W M; Middeldorp, S; Cannegieter, S C

    2016-12-01

    Essentials In 2014, World Thrombosis Day (WTD) was initiated to increase global awareness of thrombosis. Google Trends can be used freely to monitor digital information seeking behavior. We used Google Trends data to assess the impact of WTD on internet searches on venous thrombosis. The WTD period was associated with more searches on thrombosis compared to control periods. Background World Thrombosis Day (WTD) was launched in 2014 and is to be held every year to increase global awareness of venous thrombosis. Measuring the impact of health awareness days is challenging; however, use of internet-based data seems promising. Methods Google Trends data were used to quantify digital searches for 'venous thrombosis' worldwide and 'trombose' in the Netherlands. The relative search volume (RSV), which is the proportion of the term of interest amongst all Google searches for a specific region and timeframe was used. Mean differences for 4 weeks surrounding WTD (period of interest) and the remaining weeks of the year (control period) were estimated with 95% confidence intervals (95% CI). This was done for 2014, 2015 and 2009-2013 (control years). Results and discussion Mean differences in RSV for worldwide searches were 2.9 (95% CI, -8.2, 14.1) in 2014 and 10.5 (95% CI, 0.4, 20.5) in 2015. These figures were 15.3 (95% CI, 4.7, 25.8) and 15.9 (95% CI, 7.8, 24.1) for the Netherlands, respectively. Relatively, this corresponds to an increase in RSV of 3.9% and 13.9% for 2014 and 2015 worldwide and a 21.9% and 23.3% increase for 2014 and 2015 in the Netherlands. There was one control year with an increase in RSV in the WTD period. Conclusion In 2014 and 2015 WTD was associated with an increase in digital information seeking on venous thrombosis worldwide. This association was more pronounced in 2015 than in 2014. © 2016 International Society on Thrombosis and Haemostasis.

  13. 14 CFR 29.481 - Tail-down landing conditions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Tail-down landing conditions. 29.481 Section 29.481 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... Tail-down landing conditions. (a) The rotorcraft is assumed to be in the maximum nose-up attitude...

  14. 14 CFR 27.481 - Tail-down landing conditions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Tail-down landing conditions. 27.481 Section 27.481 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... Tail-down landing conditions. (a) The rotorcraft is assumed to be in the maximum nose-up attitude...

  15. From Globular Clusters to Tidal Dwarfs: Structure Formation in Tidal Tails

    NASA Astrophysics Data System (ADS)

    Knierman, K.; Hunsberger, S.; Gallagher, S.; Charlton, J.; Whitmore, B.; Hibbard, J.; Kundu, A.; Zaritsky, D.

    1999-12-01

    Galaxy interactions trigger star formation in tidal debris. How does this star formation depend on the local and global physical conditions? Using WFPC2/HST images, we investigate the range of structure within tidal tails of four classic ``Toomre Sequence'' mergers: NGC 4038/9 (``Antennae''), NGC 7252 (``Atoms for Peace''), NGC 3921, and NGC 3256. These tails contain a variety of stellar associations with sizes from globular clusters up to dwarf Irregulars. We explore whether there is a continuum between the two extremes. Our eight fields sample seven tidal tails at a variety of stages in the evolutionary sequence. Some of these tails are rich in HI while others are HI poor. Large tidal dwarfs are embedded in three of the tails. Using V and I WFPC2 images, we measure luminosities and colors of substructures within the tidal tails. The properties of globular cluster candidates in the tails will be contrasted with those of the hundreds of young clusters in the central regions of these mergers. We address whether globular clusters form and survive in the tidal tails and whether tidal dwarfs are composed of only young stars. By comparing the properties of structures in the tails of the four mergers with different ages, we examine systematic evolution of structure along the evolutionary sequence and as a function of HI content. We acknowledge support from NASA through STScI, and from NSF for an REU supplement for Karen Knierman.

  16. On the Hydrodynamics of Anomalocaris Tail Fins.

    PubMed

    Sheppard, K A; Rival, D E; Caron, J-B

    2018-04-25

    Anomalocaris canadensis, a soft-bodied stem-group arthropod from the Burgess Shale, is considered the largest predator of the Cambrian period. Thanks to a series of lateral flexible lobes along its dorso-ventrally compressed body, it is generally regarded as an efficient swimmer, well-adapted to its predatory lifestyle. Previous theoretical hydrodynamic simulations have suggested a possible optimum in swimming performance when the lateral lobes performed as a single undulatory lateral fin, comparable to the pectoral fins in skates and rays. However, the role of the unusual fan-like tail of Anomalocaris has not been previously explored. Swimming efficiency and maneuverability deduced from direct hydrodynamic analysis are here studied in a towing tank facility using a three-vane physical model designed as an abstraction of the tail fin. Through direct force measurements, it was found that the model exhibited a region of steady-state lift and drag enhancement at angles of attack greater than 25° when compared to a triangular-shaped reference model. This would suggest that the resultant normal force on the tail fin of Anomalocaris made it well-suited for turning maneuvers, giving it the ability to turn quickly and through small radii of curvature. These results are consistent with an active predatory lifestyle, although detailed kinematic studies integrating the full organism, including the lateral lobes, would be required to test the effect of the tail fin on overall swimming performance. This study also highlights a possible example of evolutionary convergence between the tails of Anomalocaris and birds, which, in both cases, are well-adapted to efficient turning maneuvers.

  17. Evaluating a strategy to deliver vaccine to white-tailed deer at a landscape level

    USGS Publications Warehouse

    Fischer, Justin W.; Blass, Chad R.; Walter, W. David; Anderson, Charles W.; Lavelle, Michael J.; Hall, Wayne H.; VerCauterren, Kurt C.

    2016-01-01

    Effective delivery of vaccines and other pharmaceuticals to wildlife populations is needed when zoonotic diseases pose a risk to public health and natural resources or have considerable economic consequences. The objective of our study was to develop a bait-distribution strategy for potential delivery of oral bovine tuberculosis (bTB) vaccine to white-tailed deer (Odocoileus virginianus) where deer are reservoirs for the disease. During 17 February and 2 March 2011, we created a grid of experimental bait stations (n = 64) on Sandhill Wildlife Management Area, Wisconsin, USA, to assess station densities needed to attract and deliver placebo baits to free-ranging white-tailed deer and look for associations among deer density, number of bait stations per deer, and bait consumption. We placed 1 L of commercially available alfalfa cubes at bait stations 652 m apart, and monitored stations with motion-activated cameras for 5 days to document visitation and consumption by deer and nontarget species. Deer discovered 38% of all bait stations within 37 hr, on average (SE = 3.91 hr), and consumed variable amounts of bait at each station. Deer were documented in 94% of all photographs of wildlife at bait stations. We found no correlation between bait consumption and deer density or the number of bait stations per deer. We provide the first information on use of baits by free-ranging deer and nontarget wildlife to eventually vaccinate deer against bTB at a landscape level. The results of this study can further the development of strategies in delivery of pharmaceuticals to free-ranging white-tailed deer.

  18. Chronic wasting disease infection patterns in female white-tailed deer related to demographics, genetic relationships, and spatial proximity of infected deer in southern Wisconsin

    USGS Publications Warehouse

    Grear, Daniel A.

    2006-01-01

    Chronic wasting disease (CWD) is a fatal disease of white-tailed deer (Odocoileus virginianus) caused by transmissible protease resistant prions. Since the discovery of CWD in southern Wisconsin in 2001, more than 20,000 deer have been removed from a >2,500 km2 disease eradication zone surrounding the three initial cases. Nearly all deer removed were tested for CWD infection and sex, age, and harvest location were recorded. Our analysis used data from a 310 kin2 core study area where disease prevalence was higher than surrounding areas. We found no difference in harvest rates between CWD infected and non-infected deer. Ow results show that the probability of infection increased with age and that adult males were more likely to be infected than adult females. Six fawns tested positive for CWD, five fawns from the core study area, including the youngest (5 months) kee-ranging cervid to test positive. The increase in male prevalence with age is nearly twice the increase found in females. We concluded that CWD is not randomly distributed among deer and that differential transmission among sex and age classes is likely driving the observed patterns in disease prevalence. We discuss alternative hypotheses for CWD transmission and spread and, in addition, discuss several possible non-linear relationships between prevalence and age. Understanding CWD transmission in free-ranging cervid populations will be essential to the development of strategies to manage this disease in areas where CWD is found as well as for surveillance strategies in areas where CWD threatens to spread.

  19. Postautotomy tail activity in the Balearic lizard, Podarcis lilfordi

    NASA Astrophysics Data System (ADS)

    Pafilis, Panayiotis; Pérez-Mellado, Valentín; Valakos, Efstratios

    2008-03-01

    Caudal autotomy is an effective antipredator strategy widespread among lizards. The shed tail thrashes vigorously for long periods to distract the predator and facilitate the lizard’s escape. This movement is maintained by energy supplied by the anaerobic conversion of glycogen into lactate. It has been suggested that lactate accumulation serves as an index for the vigor of tail thrashing. We made three predictions: (1) tail loss frequency should be higher under heavier predation regime, (2) the duration of postautotomy tail movement should be extended in populations under heavy predation pressure as an adaptation to the higher risk and the increased need for defense, and (3) as result, lactate in these tail tissues should be concentrated at higher levels. To eliminate the impact of phylogeny and environmental factors on the interpretation of our result, we focused exclusively on one species, the Balearic lizard ( Podarcis lilfordi). We studied three populations under different predation pressure but sharing the same climatic conditions. We found no differences among the studied populations either in postautotomy duration of tail movement or in levels of final lactate accumulation while autotomy frequency was higher where predation pressure was more intense. Τail loss effectiveness is directly influenced by the level of predation, while secondary features of the trait appear to remain independent from the impact of environment.

  20. Postsacral vertebral morphology in relation to tail length among primates and other mammals.

    PubMed

    Russo, Gabrielle A

    2015-02-01

    Tail reduction/loss independently evolved in a number of mammalian lineages, including hominoid primates. One prerequisite to appropriately contextualizing its occurrence and understanding its significance is the ability to track evolutionary changes in tail length throughout the fossil record. However, to date, the bony correlates of tail length variation among living taxa have not been comprehensively examined. This study quantifies postsacral vertebral morphology among living primates and other mammals known to differ in relative tail length (RTL). Linear and angular measurements with known biomechanical significance were collected on the first, mid-, and transition proximal postsacral vertebrae, and their relationship with RTL was assessed using phylogenetic generalized least-squares regression methods. Compared to shorter-tailed primates, longer-tailed primates possess a greater number of postsacral vertebral features associated with increased proximal tail flexibility (e.g., craniocaudally longer vertebral bodies), increased intervertebral body joint range of motion (e.g., more circularly shaped cranial articular surfaces), and increased leverage of tail musculature (e.g., longer spinous processes). These observations are corroborated by the comparative mammalian sample, which shows that distantly related short-tailed (e.g., Phascolarctos, Lynx) and long-tailed (e.g., Dendrolagus, Acinonyx) nonprimate mammals morphologically converge with short-tailed (e.g., Macaca tonkeana) and long-tailed (e.g., Macaca fascicularis) primates, respectively. Multivariate models demonstrate that the variables examined account for 70% (all mammals) to 94% (only primates) of the variance in RTL. Results of this study may be used to infer the tail lengths of extinct primates and other mammals, thereby improving our understanding about the evolution of tail reduction/loss. © 2014 Wiley Periodicals, Inc.

  1. Spectral induced polarization (SIP) response of mine tailings.

    PubMed

    Placencia-Gómez, Edmundo; Parviainen, Annika; Slater, Lee; Leveinen, Jussi

    2015-02-01

    Mine tailings impoundments are a source of leachates known as acid mine drainage (AMD) which can pose a contamination risk for surrounding surface and groundwater. Methodologies which can help management of this environmental issue are needed. We carried out a laboratory study of the spectral induced polarization (SIP) response of tailings from the Haveri Au-Cu mine, SW Finland. The primary objectives were, (1) to determine possible correlations between SIP parameters and textural properties associated with oxidative-weathering mechanisms, mineralogical composition and metallic content, and (2) to evaluate the effects of the pore water chemistry on SIP parameters associated with redox-inactive and redox-active electrolytes varying in molar concentration, conductivity and pH. The Haveri tailings exhibit well defined relaxation spectra between 100 and 10,000Hz. The relaxation magnitudes are governed by the in-situ oxidative-weathering conditions on sulphide mineral surfaces contained in the tailings, and decrease with the oxidation degree. The oxidation-driven textural variation in the tailings results in changes to the frequency peak of the phase angle, the imaginary conductivity and chargeability, when plotted versus the pore water conductivity. In contrast, the real and the formation electrical conductivity components show a single linear dependence on the pore water conductivity. The increase of the pore water conductivity (dominated by the increase of ions concentration in solution) along with a transition to acidic conditions shifts the polarization peak towards higher frequencies. These findings show the unique sensitivity of the SIP method to potentially discriminate AMD discharges from reactive oxidation zones in tailings, suggesting a significant advantage for monitoring threatened aquifers. Copyright © 2014 Elsevier B.V. All rights reserved.

  2. Spectral induced polarization (SIP) response of mine tailings

    NASA Astrophysics Data System (ADS)

    Placencia-Gómez, Edmundo; Parviainen, Annika; Slater, Lee; Leveinen, Jussi

    2015-02-01

    Mine tailings impoundments are a source of leachates known as acid mine drainage (AMD) which can pose a contamination risk for surrounding surface and groundwater. Methodologies which can help management of this environmental issue are needed. We carried out a laboratory study of the spectral induced polarization (SIP) response of tailings from the Haveri Au-Cu mine, SW Finland. The primary objectives were, (1) to determine possible correlations between SIP parameters and textural properties associated with oxidative-weathering mechanisms, mineralogical composition and metallic content, and (2) to evaluate the effects of the pore water chemistry on SIP parameters associated with redox-inactive and redox-active electrolytes varying in molar concentration, conductivity and pH. The Haveri tailings exhibit well defined relaxation spectra between 100 and 10,000 Hz. The relaxation magnitudes are governed by the in-situ oxidative-weathering conditions on sulphide mineral surfaces contained in the tailings, and decrease with the oxidation degree. The oxidation-driven textural variation in the tailings results in changes to the frequency peak of the phase angle, the imaginary conductivity and chargeability, when plotted versus the pore water conductivity. In contrast, the real and the formation electrical conductivity components show a single linear dependence on the pore water conductivity. The increase of the pore water conductivity (dominated by the increase of ions concentration in solution) along with a transition to acidic conditions shifts the polarization peak towards higher frequencies. These findings show the unique sensitivity of the SIP method to potentially discriminate AMD discharges from reactive oxidation zones in tailings, suggesting a significant advantage for monitoring threatened aquifers.

  3. Anisotropic Electron Tail Generation during Tearing Mode Magnetic Reconnection

    NASA Astrophysics Data System (ADS)

    Dubois, Ami

    2017-10-01

    Magnetic reconnection (MR) plays an important role in particle transport, energization, and acceleration in space, astrophysical, and laboratory plasmas. In the MST RFP, discrete MR events release large amounts of energy from the equilibrium magnetic field, a large fraction of which is transferred to the ions in a non-collisional process. Key features are anisotropic heating, mass and charge dependence, and energetic ion tail formation. Unlike the ions, the thermal electron temperature decreases at MR events, which is consistent with enhanced electron heat transport due to increased magnetic stochasticity. However, new high-speed x-ray spectrum measurements reveal transient formation of a non-Maxwellian energetic electron tail during MR. The energetic tail is characterized by a power-law, E-γ, with the spectral index (γ) decreasing from 4.2 to 2.2 at MR, and then increasing rapidly to 6.8 due to increased stochastic transport. The x-ray emission peaks in a radial view and is symmetric in the toroidal direction, indicating an anisotropic electron tail is generated. The toroidal symmetry of the electron tail implies runaway acceleration is not a dominant process, consistent with the net emf, ηJll, being smaller than the Dreicer field. Modeling of bremsstrahlung emission shows that a power-law electron tail distribution that is localized near the magnetic axis will yield strong perpendicular anisotropy, consistent with x-ray measurements in the radial and toroidal views. A strong correlation between high energy x-ray flux and tearing mode dynamics suggests a turbulent mechanism is active. This implies that the electron tail formation most likely results from a turbulent wave-particle interaction. This work is supported by the US DOE and NSF.

  4. Comparing Phlebotomy by Tail Tip Amputation, Facial Vein Puncture, and Tail Vein Incision in C57BL/6 Mice by Using Physiologic and Behavioral Metrics of Pain and Distress

    PubMed Central

    Moore, Elizabeth S; Cleland, Thomas A; Williams, Wendy O; Peterson, Christine M; Singh, Bhupinder; Southard, Teresa L; Pasch, Bret; Labitt, Rachael N; Daugherity, Erin K

    2017-01-01

    Tail tip amputation with minimal restraint is not widely used for mouse phlebotomy. In part, this infrequency may reflect policies influenced by tail tip amputation procedures for genotyping, which involve greater handling and tissue removal. To assess tail tip amputation with minimal restraint as a phlebotomy technique, we compared it with 2 more common methods: scruffing with facial vein puncture and lateral tail vein incision with minimal restraint. Blood glucose levels, audible and ultrasonic vocalizations, postphlebotomy activity and grooming behavior, open field and elevated plus maze behaviors, nest-building scores, and histologic changes at the phlebotomy site were evaluated. Mice in the facial vein phlebotomy group produced more audible vocalizations, exhibited lower postphlebotomy activity in the open field, and had more severe histologic changes than did mice in the tail incision and tail tip amputation groups. Facial vein phlebotomy did not affect grooming behavior relative to sham groups, whereas tail vein incision—but not tail tip amputation—increased tail grooming compared with that in control mice. Blood glucose levels, nest-building scores, and elevated plus maze behavior did not differ between groups, and no mice in any group produced ultrasonic vocalizations. Tail tip amputation mice did not perform differently than sham mice in any metric analyzed, indicating that this technique is a potentially superior method of blood collection in mice in terms of animal wellbeing. PMID:28535866

  5. Comparing Phlebotomy by Tail Tip Amputation, Facial Vein Puncture, and Tail Vein Incision in C57BL/6 Mice by Using Physiologic and Behavioral Metrics of Pain and Distress.

    PubMed

    Moore, Elizabeth S; Cleland, Thomas A; Williams, Wendy O; Peterson, Christine M; Singh, Bhupinder; Southard, Teresa L; Pasch, Bret; Labitt, Rachael N; Daugherity, Erin K

    2017-05-01

    Tail tip amputation with minimal restraint is not widely used for mouse phlebotomy. In part, this infrequency may reflect policies influenced by tail tip amputation procedures for genotyping, which involve greater handling and tissue removal. To assess tail tip amputation with minimal restraint as a phlebotomy technique, we compared it with 2 more common methods: scruffing with facial vein puncture and lateral tail vein incision with minimal restraint. Blood glucose levels, audible and ultrasonic vocalizations, postphlebotomy activity and grooming behavior, open field and elevated plus maze behaviors, nest-building scores, and histologic changes at the phlebotomy site were evaluated. Mice in the facial vein phlebotomy group produced more audible vocalizations, exhibited lower postphlebotomy activity in the open field, and had more severe histologic changes than did mice in the tail incision and tail tip amputation groups. Facial vein phlebotomy did not affect grooming behavior relative to sham groups, whereas tail vein incision-but not tail tip amputation-increased tail grooming compared with that in control mice. Blood glucose levels, nest-building scores, and elevated plus maze behavior did not differ between groups, and no mice in any group produced ultrasonic vocalizations. Tail tip amputation mice did not perform differently than sham mice in any metric analyzed, indicating that this technique is a potentially superior method of blood collection in mice in terms of animal wellbeing.

  6. Assessment of Phytostabilization Success in Metalliferous Acid Mine Tailings

    NASA Astrophysics Data System (ADS)

    Wang, Y.; Root, R. A.; Hammond, C.; Amistadi, M. K.; Maier, R. M.; Chorover, J.

    2014-12-01

    Legacy mine tailings are a significant source of metal(loid)s due to wind and water erosion, especially in the arid southwest, and exposure to fugative dusts presents a health risk to surrounding populations. Compost assisted phytostabilization has been implemented to reduce off site emissions at the Iron King Mine U.S. Superfund Site in central Arizona, concurrent with a greenhouse mesocosm study for detailed study of subsurface mechanisms. Quantification of plant available toxic metal(loid)s in the amended tailings was accessed with a targeted single extraction of diethylenetriaminepentaactic acid (DTPA). Greenhouse mesocosms (1m dia, 0.4 m deep), run in triplicate, mimicked field treatments with: i) tailings only control (TO), ii) tailings plus 15 wt% compost (TC), iii) TC + quailbush seeds (TCA), and iv) TC + buffalo grass seeds (TCB). Core samples collected at 3-month intervals for 1 year were dissected by depth (10 cm each) for analysis. DTPA results indicated that compost treated samples decreased plant availability of Al, As, Cd, Cu, Fe, and Pb but increased Mn and Zn compared with TO. TCB decreased plant available metal(loid)s at all depths, whereas TCA plant available Al, As, Cd, Cu, Fe, Mn and Zn increased in the deeper 20-30cm and 30-40 cm relative to TCB. Samples from the greenhouse were compared to tailings from both the field site and tailings impacted soils used to grow vegetables. Mineral transformations and metal complexation, in the pre- and post-extracted tailings were analyzed by synchrotron transmission XRD and FTIR spectroscopy. The temporal change in plant available metal(loid)s in response to phytostabilization indicates mineralogical alteration that improves soil quality by reducing plant available metal(loid)s. These results will aid in the understanding and efficacy of phytostabilization as a means of remediating and reducing toxicity on mine tailings as well as providing information on health risk management in the region.

  7. Waiting time distribution for continuous stochastic systems

    NASA Astrophysics Data System (ADS)

    Gernert, Robert; Emary, Clive; Klapp, Sabine H. L.

    2014-12-01

    The waiting time distribution (WTD) is a common tool for analyzing discrete stochastic processes in classical and quantum systems. However, there are many physical examples where the dynamics is continuous and only approximately discrete, or where it is favourable to discuss the dynamics on a discretized and a continuous level in parallel. An example is the hindered motion of particles through potential landscapes with barriers. In the present paper we propose a consistent generalization of the WTD from the discrete case to situations where the particles perform continuous barrier crossing characterized by a finite duration. To this end, we introduce a recipe to calculate the WTD from the Fokker-Planck (Smoluchowski) equation. In contrast to the closely related first passage time distribution (FPTD), which is frequently used to describe continuous processes, the WTD contains information about the direction of motion. As an application, we consider the paradigmatic example of an overdamped particle diffusing through a washboard potential. To verify the approach and to elucidate its numerical implications, we compare the WTD defined via the Smoluchowski equation with data from direct simulation of the underlying Langevin equation and find full consistency provided that the jumps in the Langevin approach are defined properly. Moreover, for sufficiently large energy barriers, the WTD defined via the Smoluchowski equation becomes consistent with that resulting from the analytical solution of a (two-state) master equation model for the short-time dynamics developed previously by us [Phys. Rev. E 86, 061135 (2012), 10.1103/PhysRevE.86.061135]. Thus, our approach "interpolates" between these two types of stochastic motion. We illustrate our approach for both symmetric systems and systems under constant force.

  8. Effects of submarine mine tailings on macrobenthic community structure and ecosystem processes.

    PubMed

    Trannum, Hilde C; Gundersen, Hege; Escudero-Oñate, Carlos; Johansen, Joachim T; Schaanning, Morten T

    2018-07-15

    A mesocosm experiment with intact benthic communities was conducted to evaluate the effects of mine tailings on benthic community structure and biogeochemical processes. Two types of tailings were supplied from process plants using flotation and flocculation chemicals, while a third type was absent of added chemicals. All tailings impacted the sediment community at thin layers, and through more mechanisms than merely hypersedimentation. In general, the strongest impact was observed in a very fine-grained tailings containing flotation chemicals. The second strongest occurred in tailings with no process chemicals. The tailings with flocculation chemicals initiated the weakest response. Fluxes of oxygen, nitrate and ammonium provided some indications on biodegradation of organic phases. Release of phosphate and silicate decreased with increasing layer thickness of all three tailings. A threshold level of 2cm was identified both for faunal responses and for fluxes of phosphate and silicate. The particular impact mechanisms should receive more attention in future studies in order to minimize the environmental risk associated with tailings disposal. Copyright © 2018 Elsevier B.V. All rights reserved.

  9. Evaluation of metal mobility from copper mine tailings in northern Chile.

    PubMed

    Lam, Elizabeth J; Gálvez, M E; Cánovas, M; Montofré, I L; Rivero, D; Faz, A

    2016-06-01

    This work shows the results obtained on a copper mine tailing in the Antofagasta Region, Chile. The tailing was classified as saline-sodic with high concentrations of metals, especially Cu and Fe, with pH 8.4. Our objectives were to (1) compare the physicochemical properties of the tailing with surrounding soils of the mine under study, and (2) evaluate the effect of two amendments (CaCO3 and compost) and their mixtures on Cu(2+), Mn, Fe, Zn, Mg(2+), and K(+) and Ca(2+), SO4 (2-), NO3 (-), and PO4 (3-) leaching. The data obtained were submitted to variance and covariance analysis. The results from the comparison between both substrates showed that in general, the tailing presented greater content of metals. Regarding tailing leaching, pH, electrical conductivity (EC), and concentration of the elements of interest were measured. The statistical analysis showed that Cu(2+) leaching and immobilization of Fe occurred to the greatest extent with compost. The EC decreased throughout the experiment with irrigation and increased upon treatment with compost. The major interactions found among the chemical parameters were (1) tailings without treatment, Cu(2+)/Fe and NO3 (-)/SO4 (2-); (2) tailings treated with CaCO3, Cu(2+)/K(+); (3) tailings treated with compost, NO3 (-)/SO4 (-2) and EC/Cu(2+); and (4) tailings treated with both amendments, EC/Fe and Cu(2+)/Fe. The ANOVA showed that the number of irrigations and the amendments statistically significantly affected the copper mobility and the organic amendment significantly influenced the iron mobility.

  10. Graphite tail powder and liquid biofertilizer as trace elements source for ground nut

    NASA Astrophysics Data System (ADS)

    Hindersah, Reginawanti; Setiawati, M. Rochimi; Fitriatin, B. Natalie; Suryatama, Pujawati; Asmiran, Priyanka; Panatarani, Camellia; Joni, I. Made

    2018-02-01

    Utilization of graphite tail waste from the mineral beneficiation processing is very important since it contain significant amount of essential minerals which are necessary for plant growth. These mineral are required in biochemical processes and mainly play an important role as cofactor in enzymatic reaction. The objective of this research is to investigate the performance of graphite tail on supporting plant growth and yield of ground nut (Arachishypogeae L.). A field experiment has been performed to test the performance of mixed graphite tail and reduced organic matter dose. The graphite tail size were reduced to various sieved size, -80 mesh, -100 mesh and -200 mesh. The experiment was setup in randomized block design with 4 treatments and 6 replications for each treatment, while the control plot is received without graphite tail. The results demonstrated that reduced organic matter along with -200 mesh tail has potentially decreased plant height at the end of vegetative growth stage, in contrast for to -80 mesh tail amendment increased individual fresh plant biomass. Statistically, there was no change of plant nodule, individual shoot fresh and dry weight, root nodule, number of pod following any mesh of graphite tail amendment. Reducing organic matter while adding graphite tail of 5% did not change bean weight in all plot. In contrast, reduced organic matter along with 80-mesh graphite tail amendment improved the nut yield per plot. This experiment suggests that graphite tail, mainly -80 mesh graphite tail can be possibly used in legume production.

  11. Time course for tail regression during metamorphosis of the ascidian Ciona intestinalis.

    PubMed

    Matsunobu, Shohei; Sasakura, Yasunori

    2015-09-01

    In most ascidians, the tadpole-like swimming larvae dramatically change their body-plans during metamorphosis and develop into sessile adults. The mechanisms of ascidian metamorphosis have been researched and debated for many years. Until now information on the detailed time course of the initiation and completion of each metamorphic event has not been described. One dramatic and important event in ascidian metamorphosis is tail regression, in which ascidian larvae lose their tails to adjust themselves to sessile life. In the present study, we measured the time associated with tail regression in the ascidian Ciona intestinalis. Larvae are thought to acquire competency for each metamorphic event in certain developmental periods. We show that the timing with which the competence for tail regression is acquired is determined by the time since hatching, and this timing is not affected by the timing of post-hatching events such as adhesion. Because larvae need to adhere to substrates with their papillae to induce tail regression, we measured the duration for which larvae need to remain adhered in order to initiate tail regression and the time needed for the tail to regress. Larvae acquire the ability to adhere to substrates before they acquire tail regression competence. We found that when larvae adhered before they acquired tail regression competence, they were able to remember the experience of adhesion until they acquired the ability to undergo tail regression. The time course of the events associated with tail regression provides a valuable reference, upon which the cellular and molecular mechanisms of ascidian metamorphosis can be elucidated. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. Progress in our understanding of cometary dust tails

    NASA Technical Reports Server (NTRS)

    Sekanina, Z.

    1976-01-01

    Various analytical techniques are employed to analyze observations on the character, composition, and size distribution of solid particles in cometary dust tails. Emphasized is the mechanical theory that includes solar gravitational attraction and solar radiation pressure to explain dust particle motions in cometary tails, as well as interactions between dust and plasma.

  13. ArrayVigil: a methodology for statistical comparison of gene signatures using segregated-one-tailed (SOT) Wilcoxon's signed-rank test.

    PubMed

    Khan, Haseeb Ahmad

    2005-01-28

    Due to versatile diagnostic and prognostic fidelity molecular signatures or fingerprints are anticipated as the most powerful tools for cancer management in the near future. Notwithstanding the experimental advancements in microarray technology, methods for analyzing either whole arrays or gene signatures have not been firmly established. Recently, an algorithm, ArraySolver has been reported by Khan for two-group comparison of microarray gene expression data using two-tailed Wilcoxon signed-rank test. Most of the molecular signatures are composed of two sets of genes (hybrid signatures) wherein up-regulation of one set and down-regulation of the other set collectively define the purpose of a gene signature. Since the direction of a selected gene's expression (positive or negative) with respect to a particular disease condition is known, application of one-tailed statistics could be a more relevant choice. A novel method, ArrayVigil, is described for comparing hybrid signatures using segregated-one-tailed (SOT) Wilcoxon signed-rank test and the results compared with integrated-two-tailed (ITT) procedures (SPSS and ArraySolver). ArrayVigil resulted in lower P values than those obtained from ITT statistics while comparing real data from four signatures.

  14. Does cortical bone thickness in the last sacral vertebra differ among tail types in primates?

    PubMed

    Nishimura, Abigail C; Russo, Gabrielle A

    2017-04-01

    The external morphology of the sacrum is demonstrably informative regarding tail type (i.e., tail presence/absence, length, and prehensility) in living and extinct primates. However, little research has focused on the relationship between tail type and internal sacral morphology, a potentially important source of functional information when fossil sacra are incomplete. Here, we determine if cortical bone cross-sectional thickness of the last sacral vertebral body differs among tail types in extant primates and can be used to reconstruct tail types in extinct primates. Cortical bone cross-sectional thickness in the last sacral vertebral body was measured from high-resolution CT scans belonging to 20 extant primate species (N = 72) assigned to tail type categories ("tailless," "nonprehensile short-tailed," "nonprehensile long-tailed," and "prehensile-tailed"). The extant dataset was then used to reconstruct the tail types for four extinct primate species. Tailless primates had significantly thinner cortical bone than tail-bearing primates. Nonprehensile short-tailed primates had significantly thinner cortical bone than nonprehensile long-tailed primates. Cortical bone cross-sectional thickness did not distinguish between prehensile-tailed and nonprehensile long-tailed taxa. Results are strongly influenced by phylogeny. Corroborating previous studies, Epipliopithecus vindobonensis was reconstructed as tailless, Archaeolemur edwardsi as long-tailed, Megaladapis grandidieri as nonprehensile short-tailed, and Palaeopropithecus kelyus as nonprehensile short-tailed or tailless. Results indicate that, in the context of phylogenetic clade, measures of cortical bone cross-sectional thickness can be used to allocate extinct primate species to tail type categories. © 2017 Wiley Periodicals, Inc.

  15. Theoretical proposal for a magnetic resonance study of charge transport in organic semiconductors

    NASA Astrophysics Data System (ADS)

    Mkhitaryan, Vagharsh

    Charge transport in disordered organic semiconductors occurs via carrier incoherent hops in a band of localized states. In the framework of continuous-time random walk the carrier on-site waiting time distribution (WTD) is one of the basic characteristics of diffusion. Besides, WTD is fundamentally related to the density of states (DOS) of localized states, which is a key feature of a material determining the optoelectric properties. However, reliable first-principle calculations of DOS in organic materials are not yet available and experimental characterization of DOS and WTD is desirable. We theoretically study the spin dynamics of hopping carriers and propose measurement schemes directly probing WTD, based on the zero-field spin relaxation and the primary (Hahn) spin echo. The proposed schemes are possible because, as we demonstrate, the long-time behavior of the zero-field relaxation and the primary echo is determined by WTD, both for the hyperfine coupling dominated and the spin-orbit coupling dominated spin dynamics. We also examine the dispersive charge transport, which is a non-Markovian sub-diffusive process characterized by non-stationarity. We show that the proposed schemes unambiguously capture the effects of non-stationarity, e.g., the aging behavior of random walks. This work was supported by the Department of Energy-Basic Energy Sciences under Contract No. DE-AC02-07CH11358.

  16. Turbulence-driven anisotropic electron tail generation during magnetic reconnection

    NASA Astrophysics Data System (ADS)

    DuBois, A. M.; Scherer, A.; Almagri, A. F.; Anderson, J. K.; Pandya, M. D.; Sarff, J. S.

    2018-05-01

    Magnetic reconnection (MR) plays an important role in particle transport, energization, and acceleration in space, astrophysical, and laboratory plasmas. In the Madison Symmetric Torus reversed field pinch, discrete MR events release large amounts of energy from the equilibrium magnetic field, a fraction of which is transferred to electrons and ions. Previous experiments revealed an anisotropic electron tail that favors the perpendicular direction and is symmetric in the parallel. New profile measurements of x-ray emission show that the tail distribution is localized near the magnetic axis, consistent modeling of the bremsstrahlung emission. The tail appears first near the magnetic axis and then spreads radially, and the dynamics in the anisotropy and diffusion are discussed. The data presented imply that the electron tail formation likely results from a turbulent wave-particle interaction and provides evidence that high energy electrons are escaping the core-localized region through pitch angle scattering into the parallel direction, followed by stochastic parallel transport to the plasma edge. New measurements also show a strong correlation between high energy x-ray measurements and tearing mode dynamics, suggesting that the coupling between core and edge tearing modes is essential for energetic electron tail formation.

  17. Experimental Study on Comprehensive Performance of Full Tailings Paste Filling in Jiaojia Gold Mine.

    NASA Astrophysics Data System (ADS)

    Zhang, Z. H.; Zou, Q. B.; Wang, P. Z.

    2017-11-01

    Filling mining method is the main method of modern underground mining. High concentration cementation is carried out using coarse tailing of +37 μm, and the mine has maturely used classified tailings paste filling technology. The gold mine studied on the performance of full tailings paste filling in order to maximize the use of tailings, reduce -37 μm fine tailings discharged into the tailing pond, reduce mining cost and eliminate security risks. The results show that: comprehensive index of full tailings paste filling is higher than that of classified tailings high concentration cementation filling, and the full tailings paste filling of 76% mass concentration has the best comprehensive index of slump, expansibility, yield stress and viscosity to meet the mining method requirements, which can effectively reduce the mining loss rate and dilution rate.

  18. Comprehensive Evaluation of Soil Near Uranium Tailings, Beishan City, China.

    PubMed

    Xun, Yan; Zhang, Xinjia; Chaoliang, Chen; Luo, Xuegang; Zhang, Yu

    2018-06-01

    To evaluate the impact of uranium tailings on soil composition and soil microbial, six soil samples at different distance from the uranium tailings (Beishan City, China) were collected for further analysis. Concentrations of radionuclides ( 238 U and 232 Th), heavy metals (Mn, Cd, Cr, Ni, Zn, and Pb) and organochlorine pesticide were determined by ICP-MS and GC, they were significantly higher than those of the control. And the Average Well Color Development as well as the Shannon, the Evenness, and the Simpson index were calculated to evaluate the soil microbial diversity. The carbon utilization model of soil microbial community was also analyzed by Biolog-eco. All results indicated that uranium tailings leaded to excessive radionuclides and heavy metals, and decreased the diversity of the soil microbial community. Our study will provide a valuable basis for soil quality evaluation around uranium tailing repositories and lay a foundation for the management and recovery of uranium tailings.

  19. Vegetation successfully prevents oxidization of sulfide minerals in mine tailings.

    PubMed

    Li, Yang; Sun, Qingye; Zhan, Jing; Yang, Yang; Wang, Dan

    2016-07-15

    The oxidization of metal sulfide in tailings causes acid mine drainage. However, it remains unclear whether vegetation prevents the oxidization of metal sulfides. The oxidization characteristics and microbial indices of the tailings in the presence of various plant species were investigated to explore the effects of vegetation on the oxidization of sulfide minerals in tailings. The pH, reducing sulfur, free iron oxides (Fed), chemical oxygen consumption (COC) and biological oxygen consumption (BOC) were measured. Key iron- and sulfur-oxidizing bacteria (Acidithiobacillus spp., Leptospirillum spp. and Thiobacillus spp.) were quantified using real-time PCR. The results indicate that vegetation growing on tailings can effectively prevent the oxidization of sulfide minerals in tailings. A higher pH and reducing-sulfur content and lower Fed were observed in the 0-30 cm depth interval in the presence of vegetation compared to bare tailings (BT). The COC gradually decreased with depth in all of the soil profiles; specifically, the COC rapidly decreased in the 10-20 cm interval in the presence of vegetation but gradually decreased in the BT profiles. Imperata cylindrica (IC) and Chrysopogon zizanoides (CZ) profiles contained the highest BOC in the 10-20 cm interval. The abundance of key iron- and sulfur-oxidizing bacteria in the vegetated tailings were significantly lower than in the BT; in particular, IC was associated with the lowest iron- and sulfur-oxidizing bacterial abundance. In conclusion, vegetation successfully prevented the oxidization of sulfide minerals in the tailings, and Imperata cylindrica is the most effective in reducing the number of iron- and sulfur-oxidizing bacteria and helped to prevent the oxidization of sulfide minerals in the long term. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Poly A tail length analysis of in vitro transcribed mRNA by LC-MS.

    PubMed

    Beverly, Michael; Hagen, Caitlin; Slack, Olga

    2018-02-01

    The 3'-polyadenosine (poly A) tail of in vitro transcribed (IVT) mRNA was studied using liquid chromatography coupled to mass spectrometry (LC-MS). Poly A tails were cleaved from the mRNA using ribonuclease T1 followed by isolation with dT magnetic beads. Extracted tails were then analyzed by LC-MS which provided tail length information at single-nucleotide resolution. A 2100-nt mRNA with plasmid-encoded poly A tail lengths of either 27, 64, 100, or 117 nucleotides was used for these studies as enzymatically added poly A tails showed significant length heterogeneity. The number of As observed in the tails closely matched Sanger sequencing results of the DNA template, and even minor plasmid populations with sequence variations were detected. When the plasmid sequence contained a discreet number of poly As in the tail, analysis revealed a distribution that included tails longer than the encoded tail lengths. These observations were consistent with transcriptional slippage of T7 RNAP taking place within a poly A sequence. The type of RNAP did not alter the observed tail distribution, and comparison of T3, T7, and SP6 showed all three RNAPs produced equivalent tail length distributions. The addition of a sequence at the 3' end of the poly A tail did, however, produce narrower tail length distributions which supports a previously described model of slippage where the 3' end can be locked in place by having a G or C after the poly nucleotide region. Graphical abstract Determination of mRNA poly A tail length using magnetic beads and LC-MS.

  1. 14 CFR 25.481 - Tail-down landing conditions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Tail-down landing conditions. 25.481... landing conditions. (a) In the tail-down attitude, the airplane is assumed to contact the ground at... prescribed in § 25.473 with— (1) V L 1 equal to V S 0 (TAS) at the appropriate landing weight and in standard...

  2. Antithrombotic effects of ethanol extract of Crataegus orientalis in the carrageenan-induced mice tail thrombosis model.

    PubMed

    Arslan, Rana; Bor, Zeynep; Bektas, Nurcan; Meriçli, Ali Hikmet; Ozturk, Yusuf

    2011-03-01

    Crataegus species (common name is Hawthorn) are medicinal plants, which have flavonoids, triterpene acids, proanthocyanidins, and organic acids as main constituents, used in the treatment of cardiovascular diseases. One of the main causes of multiple cardiovascular diseases is intravascular thrombosis and current agents, which are used for the treatment and prevention of thrombosis, have some side effects. Therefore, new antithrombotic and thrombolytic agents are still needed. Antithrombotic function of ethanol extract of Crataegus orientalis (COE) leaves was investigated in carrageenan-induced mice tail thrombosis model. Mice were injected with 40 μl (1%) carrageenan (Type I) dissolved in physiological saline by intraplantar administration in the right hind paw. After carrageenan injection, the extract was administered at the doses of 100, 200, and 300 mg/kg. Heparin was used as a positive control (10 and 100 IU). The length of tail-thrombosis was measured at 24th, 48th, and 72nd hours. 100mg/kg COE and 10IU heparin were not significant when compared to control groups at the time interval (24-72 h) that results was obtained. At 24th hour, both 200 and 300 mg/kg of COE showed a significant antithrombotic activity (p<0.05 and p<0.01, respectively). However, 200 mg/kg COE lost its significance and there was a decrease in the significance values of 300 mg/kg COE (p<0.05) at 48 and 72 h. From these results, it was concluded that COE significantly inhibited carrageenan-induced mice tail thrombosis in vivo. Copyright © 2010. Published by Elsevier Ltd.

  3. Prehensile and non-prehensile tails among syngnathid fishes: what's the difference?

    PubMed

    Neutens, Céline; de Dobbelaer, Bart; Claes, Peter; Adriaens, Dominique

    2017-02-01

    All syngnathid fishes are characterized by a tail with a vertebral column that is surrounded by dermal Plates - four per vertebra. Seahorses and pipehorses have prehensile tails, a unique characteristic among teleosts that allows them to grasp and hold onto substrates. Pipefishes, in contrast, possess a more rigid tail. Previous research (Neutens et al., 2014) showed a wide range of variation within the skeletal morphology of different members in the syngnathid family. The goal of this study is to explore whether the diversity in the three-dimensional (3D) shape of different tail types reflects grasping performance, and to what degree grasping tails occupy a different and more constrained diversity. For this, a 3D morphometrical analysis based on surfaces was performed. Four different analyses were performed on the tail skeleton of nine species exhibiting different levels of tail grasping capacities (four pipehorse, three seahorse, one pipefish and one seadragon species) to examine the intra-individual variation across the anteroposterior and dorso-ventral axis. In the two interspecific analyses, all vertebrae and all dermal plates were mutually compared. Overall, intra-individual variation was larger in species with a prehensile tail. The analysis on the vertebrae showed differences in the length and orientation of the hemal spine as well as the inclination angle between the anterior and posterior surface of the vertebral body. This was observed at an intra-individual level across the anteroposterior axis in prehensile species and at an inter-individual level between prehensile and non-prehensile species. Across the anteroposterior axis in prehensile tails, the overall shape of the plates changes from rectangular at the anterior end to square at the posterior end. Across the dorso-ventral axis, the ventral dermal plates carry a significantly longer caudal spine than the dorsal ones in all prehensile-tailed species. It can therefore be concluded that prehensile

  4. Radiation data input for the design of dry or semi-dry U tailings disposal.

    PubMed

    Kvasnicka, J

    1986-09-01

    Before discussion of design criteria for the handling of dry or semi-dry tailings, it is necessary to obtain an insight into the radiation levels associated with the tailings particles and to study the basic physical properties of dry tailings. This article presents the experimental results of assessing Ra and specific alpha-activity distribution with respect to particle size of the Ranger (RUM) and Nabarlek (QML) uranium mines dry tailings samples. The variation of Rn emanation coefficient versus particle size of dry tailings has also been measured. The nuclear-track detection technique, gamma spectrometry and alpha counting were used for the above measurements. Surface Rn flux from the hypothetical Nabarlek semi-infinite dry tailings pile is 32 Bq m-2 s-1 and the Rn flux for Ranger is 10 Bq m-2 s-1. The theoretical exposure rates for 1 m above these hypothetical tailings piles are 0.95 microC kg-1 h-1 and 0.28 microC kg-1 h-1, respectively. The derived air alpha-contamination limits (DAAC) for the tailings dust were calculated to be 1.2 Bq m-3 for workers and 0.034 Bq m-3 for a member of the public. The limit for workers corresponds to the air tailings dust concentration of 0.79 mg m-3 for QML tailings and 2.2 mg m-3 for RUM tailings. The DAAC limit for the public corresponds to the air tailings dust concentration of 0.022 mg m-3 for QML tailings and 0.064 mg m-3 for RUM tailings.

  5. Extremely High Phosphate Sorption Capacity in Cu-Pb-Zn Mine Tailings.

    PubMed

    Huang, Longbin; Li, Xiaofang; Nguyen, Tuan A H

    2015-01-01

    Elevated inorganic phosphate (Pi) concentrations in pore water of amended tailings under direct revegetation may cause toxicity in some native woody species but not native forbs or herb species, all of which are key constituents in target native plant communities for phytostabilizing base metal mine tailings. As a result, Pi sorption capacity has been quantified by a conventional batch procedure in three types of base metal mine tailings sampled from two copper (Cu)-lead (Pb)-zinc (Zn) mines, as the basis for Pi-fertiliser addition. It was found that the Pi-sorption capacity in the tailings and local soil was extremely high, far higher than highly weathered agricultural soils in literature, but similar to those of volcanic ash soils. The Langmuir P-sorption maximum was up to 7.72, 4.12, 4.02 and 3.62 mg P g-1 tailings, in the fresh tailings of mixed Cu-Pb-Zn streams (MIMTD7), the weathered tailings of mixed Cu-Pb-Zn streams (MIMTD5), EHM-TD (fresh Cu-stream, high magnetite content) and local soil (weathered shale and schist), respectively. Physicochemical factors highly correlated with the high Pi-sorption in the tailings were fine particle distribution, oxalate and dithionite-citrate-bicarbonate extractable Fe (FeO and Fed), oxalate-extractable Al and Mn, and the levels of soluble Cd and Zn, and total S and Fe. Large amounts of amorphous Fe oxides and oxyhydroxides may have been formed from the oxidation of pyritic materials and redox cycles of Fe-minerals (such as pyrite (FeS2), ankerite (Ca(Fe Mg)(CO3)2 and siderite (FeCO3), as indicated by the extractable FeO values. The likely formation of sparingly soluble Zn-phosphate in the Pb-Zn tailings containing high levels of Zn (from sphalerite ((Zn,Fe)S, ZnS, (Zn,Cd)S)) may substantially lower soluble Zn levels in the tailings through high rates of Pi-fertiliser addition. As a result, the possibility of P-toxicity in native plant species caused by the addition of soluble phosphate fertilizers would be minimal.

  6. Study on the Influence of Elevation of Tailing Dam on Stability

    NASA Astrophysics Data System (ADS)

    Wan, Shuai; Wang, Kun; Kong, Songtao; Zhao, Runan; Lan, Ying; Zhang, Run

    2017-12-01

    This paper takes Yunnan as the object of a tailing, by theoretical analysis and numerical calculation method of the effect of seismic load effect of elevation on the stability of the tailing, to analyse the stability of two point driven safety factor and liquefaction area. The Bishop method is adopted to simplify the calculation of dynamic safety factor and liquefaction area analysis using comparison method of shear stress to analyse liquefaction, so we obtained the influence of elevation on the stability of the tailing. Under the earthquake, with the elevation increased, the safety coefficient of dam body decreases, shallow tailing are susceptible to liquefy. Liquefaction area mainly concentrated in the bank below the water surface, to improve the scientific basis for the design and safety management of the tailing.

  7. Evaluation of pyritic mine tailings as a plant growth substrate.

    PubMed

    Roseby, Stuart J; Kopittke, Peter M; Mulligan, David R; Menzies, Neal W

    2017-10-01

    At the Kidston gold mine, Australia, the direct establishment of vegetation on tailings was considered as an alternative to the use of a waste rock cover. The tailings acid/base account was used to predict plant growth limitation by acidity, and thus methods capable of identifying tailings that would acidify to pH 4.5 or lower were sought. Total S was found to be poorly correlated with acid-generating sulfide, and total C was poorly correlated with acid-neutralizing carbonate, precluding the use of readily determined total S and C as predictors of net acid generation. Therefore, the selected approach used assessment of sulfide content as a predictor of acid generation, and carbonate content as a measure of the acid-neutralizing capacity available at pH 5 and above. Using this approach, the majority of tailings (67%) were found to be non-acid generating. However, areas of potentially acid-generating tailings were randomly distributed across the dam, and could only be located by intensive sampling. The limitations imposed by the large sample numbers, and costly analysis of sulfide and carbonate, make it impractical to identify and ameliorate acid-generating areas prior to vegetation establishment. However, as only a small proportion of the tailings will acidify, a strategy of re-treating acid areas following oxidation is suggested. The findings of the present study will assist in the selection of appropriate methods for the prediction of net acid generation, particularly where more conservative measurements are required to allow vegetation to be established directly in tailings. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Engineering assessment of inactive uranium mill tailings: Maybell Site, Maybell, Colorado

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1981-09-01

    Ford, Bacon and Davis Utah Inc. has reevaluated the Maybell site in order to revise the October 1977 engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at Maybell, Colorado. This engineering assessment has included the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and radiation exposures of individuals and nearby populations, the investigations of site hydrology and meteorology, and the evaluation and costing of alternative corrective actions. Radon gas released from the 2.6 million dry tons of tailings at the Maybell sitemore » constitutes the most significant environmental impact, although windblown tailings and external gamma radiation also are factors. The two alternative actions presented in this engineering assessment range from millsite decontamination with the addition of 3 m of stabilization cover material (Option I), to disposal of the tailings in a nearby open pit mine and decontamination of the tailings site (Option II). Cost estimates for the two options are about $11,700,000 for stabilization in-place and about $22,700,000 for disposal within a distance of 2 mi. Three principal alternatives for the reprocessing of the Maybell tailings were examined: (a) heap leaching; (b) treatment at an existing mill; and (c) reprocessing at a new conventional mill constructed for tailings reprocessing. The cost of the uranium recovered would be about $125 and $165/lb of U/sub 3/O/sub 8/ by heap leach and conventional plant processes, respectively. The spot market price for uranium was $25/lb early in 1981. Therefore, reprocessing the tailings for uranium recovery is not economically attractive at present.« less

  9. Notochord-derived hedgehog is essential for tail regeneration in Xenopus tadpole.

    PubMed

    Taniguchi, Yuka; Watanabe, Kenji; Mochii, Makoto

    2014-06-18

    Appendage regeneration in amphibians is regulated by the combinatorial actions of signaling molecules. The requirement of molecules secreted from specific tissues is reflected by the observation that the whole process of regeneration can be inhibited if a certain tissue is removed from the amputated stump. Interestingly, urodeles and anurans show different tissue dependencies during tail regeneration. The spinal cord is essential for tail regeneration in urodele but not in anuran larva, whereas the notochord but not the spinal cord is essential for tail regeneration in anuran tadpoles. Sonic hedgehog is one of the signaling molecules responsible for such phenomenon in axolotl, as hedgehog signaling is essential for overall tail regeneration and sonic hedgehog is exclusively expressed in the spinal cord. In order to know whether hedgehog signaling is involved in the molecular mechanism underlying the inconsistent tissue dependency for tail regeneration between anurans and urodeles, we investigated expression of hedgehog signal-related genes in the regenerating tail of Xenopus tadpole and examined the effect of the hedgehog signal inhibitor, cyclopamine, on the tail regeneration. In Xenopus, sonic hedgehog is expressed exclusively in the notochord but not in the spinal cord of the regenerate. Overall regeneration was severely impaired in cyclopamine-treated tadpoles. Notochord maturation in the regenerate, including cell alignment and vacuolation, and myofiber formation were inhibited. Proliferation of spinal cord cells in the neural ampulla and of mesenchymal cells was also impaired. As in the axolotl, hedgehog signaling is required for multiple steps in tail regeneration in the Xenopus tadpole, although the location of the Shh source is quite different between the two species. This difference in Shh localization is the likely basis for the differing tissue requirement for tail regeneration between urodeles and anurans.

  10. Notochord-derived hedgehog is essential for tail regeneration in Xenopus tadpole

    PubMed Central

    2014-01-01

    Background Appendage regeneration in amphibians is regulated by the combinatorial actions of signaling molecules. The requirement of molecules secreted from specific tissues is reflected by the observation that the whole process of regeneration can be inhibited if a certain tissue is removed from the amputated stump. Interestingly, urodeles and anurans show different tissue dependencies during tail regeneration. The spinal cord is essential for tail regeneration in urodele but not in anuran larva, whereas the notochord but not the spinal cord is essential for tail regeneration in anuran tadpoles. Sonic hedgehog is one of the signaling molecules responsible for such phenomenon in axolotl, as hedgehog signaling is essential for overall tail regeneration and sonic hedgehog is exclusively expressed in the spinal cord. In order to know whether hedgehog signaling is involved in the molecular mechanism underlying the inconsistent tissue dependency for tail regeneration between anurans and urodeles, we investigated expression of hedgehog signal-related genes in the regenerating tail of Xenopus tadpole and examined the effect of the hedgehog signal inhibitor, cyclopamine, on the tail regeneration. Results In Xenopus, sonic hedgehog is expressed exclusively in the notochord but not in the spinal cord of the regenerate. Overall regeneration was severely impaired in cyclopamine-treated tadpoles. Notochord maturation in the regenerate, including cell alignment and vacuolation, and myofiber formation were inhibited. Proliferation of spinal cord cells in the neural ampulla and of mesenchymal cells was also impaired. Conclusion As in the axolotl, hedgehog signaling is required for multiple steps in tail regeneration in the Xenopus tadpole, although the location of the Shh source is quite different between the two species. This difference in Shh localization is the likely basis for the differing tissue requirement for tail regeneration between urodeles and anurans. PMID:24941877

  11. A cross-sectional study of the causes of morbidity and mortality in farmed white-tailed deer

    PubMed Central

    2005-01-01

    Abstract Two questionnaires were designed and administered. The first was to a random sample of 340 farmers of white-tailed deer (Odocoileus virginianus) in Canada and the United States. The second was a 10-year retrospective survey of deer submissions to veterinary diagnostic pathology laboratories in Canada and the United States. One-year rates of mortality and common causes of morbidity and mortality for the deer are reported. The primary diagnosis for each record was used to classify diseases into categories, such as parasitic, infectious, toxicological, and neoplastic. Submissions were further classified according to the anatomical location, the pathological change, and the etiology associated with each lesion. Trauma was the most important reported cause of farmed white-tailed deer mortality; necrobacillosis was a major cause of morbidity and mortality, especially in fawns. PMID:16048010

  12. Bacterial diversity and composition of an alkaline uranium mine tailings-water interface.

    PubMed

    Khan, Nurul H; Bondici, Viorica F; Medihala, Prabhakara G; Lawrence, John R; Wolfaardt, Gideon M; Warner, Jeff; Korber, Darren R

    2013-10-01

    The microbial diversity and biogeochemical potential associated with a northern Saskatchewan uranium mine water-tailings interface was examined using culture-dependent and -independent techniques. Morphologically-distinct colonies from uranium mine water-tailings and a reference lake (MC) obtained using selective and non-selective media were selected for 16S rRNA gene sequencing and identification, revealing that culturable organisms from the uranium tailings interface were dominated by Firmicutes and Betaproteobacteria; whereas, MC organisms mainly consisted of Bacteroidetes and Gammaproteobacteria. Ion Torrent (IT) 16S rRNA metagenomic analysis carried out on extracted DNA from tailings and MC interfaces demonstrated the dominance of Firmicutes in both of the systems. Overall, the tailings-water interface environment harbored a distinct bacterial community relative to the MC, reflective of the ambient conditions (i.e., total dissolved solids, pH, salinity, conductivity, heavy metals) dominating the uranium tailings system. Significant correlations among the physicochemical data and the major bacterial groups present in the tailings and MC were also observed. Presence of sulfate reducing bacteria demonstrated by culture-dependent analyses and the dominance of Desulfosporosinus spp. indicated by Ion Torrent analyses within the tailings-water interface suggests the existence of anaerobic microenvironments along with the potential for reductive metabolic processes.

  13. Asymmetric breathing motions of nucleosomal DNA and the role of histone tails

    NASA Astrophysics Data System (ADS)

    Chakraborty, Kaushik; Loverde, Sharon M.

    2017-08-01

    The most important packing unit of DNA in the eukaryotic cell is the nucleosome. It undergoes large-scale structural re-arrangements during different cell cycles. For example, the disassembly of the nucleosome is one of the key steps for DNA replication, whereas reassembly occurs after replication. Thus, conformational dynamics of the nucleosome is crucial for different DNA metabolic processes. We perform three different sets of atomistic molecular dynamics simulations of the nucleosome core particle at varying degrees of salt conditions for a total of 0.7 μs simulation time. We find that the conformational dynamics of the nucleosomal DNA tails are oppositely correlated from each other during the initial breathing motions. Furthermore, the strength of the interaction of the nucleosomal DNA tail with the neighboring H2A histone tail modulates the conformational state of the nucleosomal DNA tail. With increasing salt concentration, the degree of asymmetry in the conformation of the nucleosomal DNA tails decreases as both tails tend to unwrap. This direct correlation between the asymmetric breathing motions of the DNA tails and the H2A histone tails, and its decrease at higher salt concentrations, may play a significant role in the molecular pathway of unwrapping.

  14. Determination of the reaction rate coefficient of sulphide mine tailings deposited under water.

    PubMed

    Awoh, Akué Sylvette; Mbonimpa, Mamert; Bussière, Bruno

    2013-10-15

    The efficiency of a water cover to limit dissolved oxygen (DO) availability to underlying acid-generating mine tailings can be assessed by calculating the DO flux at the tailings-water interface. Fick's equations, which are generally used to calculate this flux, require knowing the effective DO diffusion coefficient (Dw) and the reaction (consumption) rate coefficient (Kr) of the tailings, or the DO concentration profile. Whereas Dw can be accurately estimated, few studies have measured the parameter Kr for submerged sulphide tailings. The objective of this study was to determine Kr for underwater sulphide tailings in a laboratory experiment. Samples of sulphide mine tailings (an approximately 6 cm layer) were placed in a cell under a water cover (approximately 2 cm) maintained at constant DO concentration. Two tailings were studied: TA1 with high sulphide content (83% pyrite) and TA2 with low sulphide content (2.8% pyrite). DO concentration was measured with a microelectrode at various depths above and below the tailings-water interface at 1 mm intervals. Results indicate that steady-state condition was rapidly attained. As expected, a diffusive boundary layer (DBL) was observed in all cases. An iterative back-calculation process using the numerical code POLLUTEv6 and taking the DBL into account provided the Kr values used to match calculated and experimental concentration profiles. Kr obtained for tailings TA1 and TA2 was about 80 d(-1) and 6.5 d(-1), respectively. For comparison purposes, Kr obtained from cell tests on tailings TA1 was lower than Kr calculated from the sulphate production rate obtained from shake-flask tests. Steady-state DO flux at the water-tailings interface was then calculated with POLLUTEv6 using tailings characteristics Dw and Kr. For the tested conditions, DO flux ranged from 608 to 758 mg O2/m(2)/d for tailings TA1 and from 177 to 221 mg O2/m(2)/d for tailings TA2. The impact of placing a protective layer of inert material over

  15. Casein Kinase 2 Reverses Tail-Independent Inhibition of Kinesin-1

    NASA Astrophysics Data System (ADS)

    Xu, Jing; Shu, Zhanyong; Anand, Preetha; Reddy, Babu; Cermelli, Silvia; Whisenant, Thomas; King, Stephen; Bardwell, Lee; Huang, Lan; Gross, Steven

    2011-03-01

    Kinesin-1 is a plus-end microtubule-based molecular motor, and defects in kinesin transport are linked to diseases including neurodegeneration. Kinesin can auto-inhibit via a direct head-tail interaction, but is believed to be active otherwise. In contrast, this study uncovers a fast but reversible inhibition distinct from the canonical auto-inhibition pathway. The majority of the initially active kinesin (full-length or tail-less) loses its ability to bind/interact with microtubule, and Casein Kinase 2 (CK2) reverses this inactivation (up to 4-fold) without altering kinesin's single motor properties. Motor phosphorylation is not required for this CK2 -mediated kinesin activation. In cultured mammalian cells, knockdown of CK2 level, but not kinase activity, was sufficient to decrease the force required to stall lipid droplet transport, consistent with a reduction in the number of active motors. We propose that CK2 forms a positive regulating complex with the motor. This study provides the first direct evidence of a protein kinase positively regulating kinesin-transport, and uncovers a pathway whereby inactive cargo-bound kinesin can be activated. This work is supported by NIGMS grants GM64624 and GM079156 to SPG, GM-74830 to LH, NIH grants GM76516 and GM60366 to LB, and AHA grant 825278F to JX.

  16. Band tailing and efficiency limitation in kesterite solar cells

    NASA Astrophysics Data System (ADS)

    Gokmen, Tayfun; Gunawan, Oki; Todorov, Teodor K.; Mitzi, David B.

    2013-09-01

    We demonstrate that a fundamental performance bottleneck for hydrazine processed kesterite Cu2ZnSn(S,Se)4 (CZTSSe) solar cells with efficiencies reaching above 11% can be the formation of band-edge tail states, which quantum efficiency and photoluminescence data indicate is roughly twice as severe as in higher-performing Cu(In,Ga)(S,Se)2 devices. Low temperature time-resolved photoluminescence data suggest that the enhanced tailing arises primarily from electrostatic potential fluctuations induced by strong compensation and facilitated by a lower CZTSSe dielectric constant. We discuss the implications of the band tails for the voltage deficit in these devices.

  17. On the mechanism of ray closure in comet tails

    NASA Astrophysics Data System (ADS)

    Ershkovich, A. I.

    The folding phenomenon of comet tail rays is explained by means of an electric drift due to convectional electric fields. This mechanism results in an angular rate of closure which reduces to that obtained by Ness and Donn (1966) if the velocity profile across the tail is linear and the plasma conductivity is ideal. Observations of both the ray closure and the disconnection events point to the phenomenon of anomalous resistivity. Magnetic fields of about 30-40 gammas in the coma and of 10 gammas in the distant tail (at 1 AU) are estimated from the MHD momentum equation.

  18. Engineering assessment of inactive uranium mill tailings, Durango Site, Durango, Colorado

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1981-06-01

    Ford, Bacon and Davis Utah Inc. has reevaluated the Durango site in order to revise the November 1977 engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at Durango, Colorado. This engineering assessment has included the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and radiation exposures of individuals and nearby populations, the investigations of site hydrology and meteorology, and the evaluation and costing of alternative corrective actions. Radon gas released from the nearly 1.6 million tons of tailings at the Durango sitemore » constitutes the most significant environmental impact, although windblown tailings and external gamma radiation also are factors. The four alternative actions presented in this engineering assessment range from millsite and off-site decontamination with the addition of 3 m of stabilization cover material (Option I), to removal of the tailings to remote disposal sites and decontamination of the tailings site (Options II through IV). Cost estimates for the seven options range from about $10,700,000 for stabilization in-place, to about $21,800,000 for disposal at a distance of about 10 mi. Three principal alternatives for the reprocessing of the Durango tailings were examined: (a) heap leaching; (b) treatment at an existing mill; and (c) reprocessing at a new conventional mill constructed for tailings reprocessing. The cost of the uranium recovered would be about $30/lb U/sub 3/O/sub 8/ by either heap leach or conventional plant processes.« less

  19. The microbiology of oil sands tailings: past, present, future.

    PubMed

    Foght, Julia M; Gieg, Lisa M; Siddique, Tariq

    2017-05-01

    Surface mining of enormous oil sands deposits in northeastern Alberta, Canada since 1967 has contributed greatly to Canada's economy but has also received negative international attention due largely to environmental concerns and challenges. Not only have microbes profoundly affected the composition and behavior of this petroleum resource over geological time, they currently influence the management of semi-solid tailings in oil sands tailings ponds (OSTPs) and tailings reclamation. Historically, microbial impacts on OSTPs were generally discounted, but next-generation sequencing and biogeochemical studies have revealed unexpectedly diverse indigenous communities and expanded our fundamental understanding of anaerobic microbial functions. OSTPs that experienced different processing and management histories have developed distinct microbial communities that influence the behavior and reclamation of the tailings stored therein. In particular, the interactions of Deltaproteobacteria and Firmicutes with methanogenic archaea impact greenhouse gas emissions, sulfur cycling, pore water toxicity, sediment biogeochemistry and densification, water usage and the trajectory of long-term mine waste reclamation. This review summarizes historical data; synthesizes current understanding of microbial diversity and activities in situ and in vitro; predicts microbial effects on tailings remediation and reclamation; and highlights knowledge gaps for future research. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  20. Plant Growth-Promoting Bacteria for Phytostabilization of Mine Tailings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grandlic, C.J.; Mendez, M.O.; Chorover, J.

    2009-05-19

    Eolian dispersion of mine tailings in arid and semiarid environments is an emerging global issue for which economical remediation alternatives are needed. Phytostabilization, the revegetation of these sites with native plants, is one such alternative. Revegetation often requires the addition of bulky amendments such as compost which greatly increases cost. We report the use of plant growth-promoting bacteria (PGPB) to enhance the revegetation of mine tailings and minimize the need for compost amendment. Twenty promising PGPB isolates were used as seed inoculants in a series of greenhouse studies to examine revegetation of an extremely acidic, high metal content tailings samplemore » previously shown to require 15% compost amendment for normal plant growth. Several isolates significantly enhanced growth of two native species, quailbush and buffalo grass, in tailings. In this study, PGPB/compost outcomes were plant specific; for quailbush, PGPB were most effective in combination with 10% compost addition while for buffalo grass, PGPB enhanced growth in the complete absence of compost. Results indicate that selected PGPB can improve plant establishment and reduce the need for compost amendment. Further, PGPB activities necessary for aiding plant growth in mine tailings likely include tolerance to acidic pH and metals.« less

  1. Microbial metabolism alters pore water chemistry and increases consolidation of oil sands tailings.

    PubMed

    Arkell, Nicholas; Kuznetsov, Petr; Kuznetsova, Alsu; Foght, Julia M; Siddique, Tariq

    2015-01-01

    Tailings produced during bitumen extraction from surface-mined oil sands ores (tar sands) comprise an aqueous suspension of clay particles that remain dispersed for decades in tailings ponds. Slow consolidation of the clays hinders water recovery for reuse and retards volume reduction, thereby increasing the environmental footprint of tailings ponds. We investigated mechanisms of tailings consolidation and revealed that indigenous anaerobic microorganisms altered porewater chemistry by producing CO and CH during metabolism of acetate added as a labile carbon amendment. Entrapped biogenic CO decreased tailings pH, thereby increasing calcium (Ca) and magnesium (Mg) cations and bicarbonate (HCO) concentrations in the porewater through dissolution of carbonate minerals. Soluble ions increased the porewater ionic strength, which, with higher exchangeable Ca and Mg, decreased the diffuse double layer of clays and increased consolidation of tailings compared with unamended tailings in which little microbial activity was observed. These results are relevant to effective tailings pond management strategies. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  2. Tail dependence and information flow: Evidence from international equity markets

    NASA Astrophysics Data System (ADS)

    Al Rahahleh, Naseem; Bhatti, M. Ishaq; Adeinat, Iman

    2017-05-01

    Bhatti and Nguyen (2012) used the copula approach to measure the tail dependence between a number of international markets. They observed that some country pairs exhibit only left-tail dependence whereas others show only right-tail. However, the flow of information from uni-dimensional (one-tail) to bi-dimensional (two-tails) between various markets was not accounted for. In this study, we address the flow of information of this nature by using the dynamic conditional correlation (DCC-GARCH) model. More specifically, we use various versions of the DCC models to explain the nexus between the information flow of international equity and to explain the stochastic forward vs. backward dynamics of financial markets based on data for a 15-year period comprising 3,782 observations. We observed that the information flow between the US and Hong Kong markets and between the US and Australian markets are bi-directional. We also observed that the DCC model captures a wider co-movement structure and inter-connectedness compared to the symmetric Joe-Clayton copula.

  3. Bacterial and chemical oxidation of pyritic mine tailings at low temperatures

    NASA Astrophysics Data System (ADS)

    Elberling, Bo; Schippers, Axel; Sand, Wolfgang

    2000-02-01

    Microbial and chemical sulfide oxidation activity and oxygen consumption was investigated in the active layer of pyritic mine tailings at Nanisivik Mine, located in a permafrost area on Baffin Island in northern Canada. Samples of tailings were collected up to a depth of 60 cm in mid-August 1998 at 4 sites, for which the metabolic activity of sulfur- and iron-oxidizing leaching bacteria besides the chemical pyrite oxidation activity were measured on 39 tailings samples and 7 samples from a natural pyritic site by calorimetry. The tailings of varying age and water content were deposited under alkaline conditions. In situ oxygen uptake rates were measured at the tailings surface every third day, prior to sampling. In addition, cell counts of iron(II), sulfur, and thiosulfate oxidizing, lithotrophic bacteria and chemoorganotrophic microorganisms were determined quantitatively by the most-probable-number technique or by agar-plating. Results show consistent pyrite oxidation rates based on in situ oxygen uptake rates, and laboratory heat output measurements. Litho- and organotrophic bacteria were found in the tailings. Calorimetric measurements revealed that the present bacterial activity is responsible for approximately one third of the ongoing oxidation. Although leaching bacteria have previously been found in the Arctic, this study is the first to prove the significance of bacterial activity in the overall pollution resulting from tailings deposited in the Arctic.

  4. Element flows associated with marine shore mine tailings deposits.

    PubMed

    Dold, Bernhard

    2006-02-01

    From 1938 until 1975, flotation tailings from the Potrerillos--El Salvador mining district (porphyry copper deposits) were discharged into the El Salado valley and transported in suspension to the sea at Chaliaral Bay, Atacama Desert, northern Chile. Over 220 Mt of tailings, averaging 0.8 +/- 0.25 wt % of pyrite, were deposited into the bay, resulting in over a 1 kilometer seaward displacement of the shoreline and an estimated 10-15 m thick tailings accumulation covering a approximately 4 km2 surface area. The Chaniaral case was classified by the United Nations Environmental Programme (UNEP) in 1983 as one of the most serious cases of marine contamination in the Pacific area. Since 1975, the tailings have been exposed to oxidation, resulting in a 70-188 cm thick low-pH (2.6-4) oxidation zone at the top with liberation of divalent metal cations, such as Cu2+, Ni2+, and Zn2+ (up to 2265 mg/L, 18.1 mg/L, and 20.3 mg/ L, respectively). Evaporation-induced transport capillarity led to metal enrichment atthe tailings surface (e.g. up to 2.4% Cu) in the form of secondary chlorides and/or sulfates (dominated by eriochalcite [CuCl.H2O] and halite). These, mainly water-soluble, secondary minerals were exposed to eolian transport in the direction of the Village of Chañaral by the predominant W-SW winds. Two element-flow directions (toward the tailings surface, via capillarity, and toward the sea) and two element groups with different geochemical behaviors (cations such as Cu, Zn, Ni, and oxyanions such as As and Mo) could be distinguished. It can be postulated, that the sea is mainly affected by the following: As, Mo, Cu, and Zn contamination, which were liberated from the oxidation zone from the tailings and mobilized through the tidal cycle, and by Cu and Zn from the subsurface waters flowing in the El Salado valley (up to 19 mg/L and 12 mg/L Zn, respectively), transported as chloro complexes at neutral pH.

  5. Computational Investigation and Validation of Twin-Tail Buffet Response Including Dynamics and Control

    NASA Technical Reports Server (NTRS)

    Kandil, Osama A.

    1998-01-01

    Multidisciplinary tools for prediction of single rectangular-tail buffet are extended to single swept-back-tail buffet in transonic-speed flow, and multidisciplinary tools for prediction and control of twin-tail buffet are developed and presented. The configuration model consists of a sharp-edged delta wing with single or twin tails that are oriented normal to the wing surface. The tails are treated as cantilevered beams fixed at the root and allowed to oscillate in both bending and torsion. This complex multidisciplinary problem is solved sequentially using three sets of equations on a dynamic single or multi-block grid structure. The first set is the unsteady, compressible, Reynolds-averaged Navier-Stokes equations which are used for obtaining the flow field vector and the aerodynamic loads on the tails. The Navier-Stokes equations are solved accurately in time using the implicit, upwind, flux-difference splitting, finite volume scheme. The second set is the coupled bending and torsion aeroelastic equations of cantilevered beams which are used for obtaining the bending and torsion deflections of the tails. The aeroelastic equations'are solved accurately in time using, a fifth-order-accurate Runge-Kutta scheme. The third set is the grid-displacement equations and the rigid-body dynamics equations, which are used for updating the grid coordinates due to the tail deflections and rigid-body motions. The tail-buffet phenomenon is predicted for highly-swept, single vertical tail placed at the plane of geometric symmetry, and for highly-swept, vertical twin tails placed at three different spanwise separation distances. The investigation demonstrates the effects of structural inertial coupling and uncoupling of the bending and torsion modes of vibration, spanwise positions of the twin-tail, angle of attack, and pitching and rolling dynamic motions of the configuration model on the tail buffet loading and response. The fundamental issue of twin-tail buffet alleviation is

  6. High emissions of greenhouse gases from grasslands on peat and other organic soils.

    PubMed

    Tiemeyer, Bärbel; Albiac Borraz, Elisa; Augustin, Jürgen; Bechtold, Michel; Beetz, Sascha; Beyer, Colja; Drösler, Matthias; Ebli, Martin; Eickenscheidt, Tim; Fiedler, Sabine; Förster, Christoph; Freibauer, Annette; Giebels, Michael; Glatzel, Stephan; Heinichen, Jan; Hoffmann, Mathias; Höper, Heinrich; Jurasinski, Gerald; Leiber-Sauheitl, Katharina; Peichl-Brak, Mandy; Roßkopf, Niko; Sommer, Michael; Zeitz, Jutta

    2016-12-01

    Drainage has turned peatlands from a carbon sink into one of the world's largest greenhouse gas (GHG) sources from cultivated soils. We analyzed a unique data set (12 peatlands, 48 sites and 122 annual budgets) of mainly unpublished GHG emissions from grasslands on bog and fen peat as well as other soils rich in soil organic carbon (SOC) in Germany. Emissions and environmental variables were measured with identical methods. Site-averaged GHG budgets were surprisingly variable (29.2 ± 17.4 t CO 2 -eq. ha -1  yr -1 ) and partially higher than all published data and the IPCC default emission factors for GHG inventories. Generally, CO 2 (27.7 ± 17.3 t CO 2  ha -1  yr -1 ) dominated the GHG budget. Nitrous oxide (2.3 ± 2.4 kg N 2 O-N ha -1  yr -1 ) and methane emissions (30.8 ± 69.8 kg CH 4 -C ha -1  yr -1 ) were lower than expected except for CH 4 emissions from nutrient-poor acidic sites. At single peatlands, CO 2 emissions clearly increased with deeper mean water table depth (WTD), but there was no general dependency of CO 2 on WTD for the complete data set. Thus, regionalization of CO 2 emissions by WTD only will remain uncertain. WTD dynamics explained some of the differences between peatlands as sites which became very dry during summer showed lower emissions. We introduced the aerated nitrogen stock (N air ) as a variable combining soil nitrogen stocks with WTD. CO 2 increased with N air across peatlands. Soils with comparatively low SOC concentrations showed as high CO 2 emissions as true peat soils because N air was similar. N 2 O emissions were controlled by the WTD dynamics and the nitrogen content of the topsoil. CH 4 emissions can be well described by WTD and ponding duration during summer. Our results can help both to improve GHG emission reporting and to prioritize and plan emission reduction measures for peat and similar soils at different scales. © 2016 John Wiley & Sons Ltd.

  7. Variability of wet troposphere delays over inland reservoirs as simulated by a high-resolution regional climate model

    NASA Astrophysics Data System (ADS)

    Clark, E.; Lettenmaier, D. P.

    2014-12-01

    Satellite radar altimetry is widely used for measuring global sea level variations and, increasingly, water height variations of inland water bodies. Existing satellite radar altimeters measure water surfaces directly below the spacecraft (approximately at nadir). Over the ocean, most of these satellites use radiometry to measure the delay of radar signals caused by water vapor in the atmosphere (also known as the wet troposphere delay (WTD)). However, radiometry can only be used to estimate this delay over the largest inland water bodies, such as the Great Lakes, due to spatial resolution issues. As a result, atmospheric models are typically used to simulate and correct for the WTD at the time of observations. The resolutions of these models are quite coarse, at best about 5000 km2 at 30˚N. The upcoming NASA- and CNES-led Surface Water and Ocean Topography (SWOT) mission, on the other hand, will use interferometric synthetic aperture radar (InSAR) techniques to measure a 120-km-wide swath of the Earth's surface. SWOT is expected to make useful measurements of water surface elevation and extent (and storage change) for inland water bodies at spatial scales as small as 250 m, which is much smaller than current altimetry targets and several orders of magnitude smaller than the models used for wet troposphere corrections. Here, we calculate WTD from very high-resolution (4/3-km to 4-km) simulations of the Weather Research and Forecasting (WRF) regional climate model, and use the results to evaluate spatial variations in WTD. We focus on six U.S. reservoirs: Lake Elwell (MT), Lake Pend Oreille (ID), Upper Klamath Lake (OR), Elephant Butte (NM), Ray Hubbard (TX), and Sam Rayburn (TX). The reservoirs vary in climate, shape, use, and size. Because evaporation from open water impacts local water vapor content, we compare time series of WTD over land and water in the vicinity of each reservoir. To account for resolution effects, we examine the difference in WRF

  8. The fecundity of fork-tailed threadfin bream (Nemipterus furcosus) in Bangka, Bangka Belitung

    NASA Astrophysics Data System (ADS)

    Utami, E.; Safitriyani, E.; Gatra Persada, Leo

    2018-04-01

    Fork-tailed threadfin bream (Nemipterus furcosus) is one of important economic fishes in Bangka. The sustainability of fork-tailed threadfin bream is threatened by degradation of natural habitat. Information of reproductive is needed for further management. The objective of this study was to examine fecundity of fork-tailed threadfin bream. The mean values of temperature was 28.83 ± 0,37°C, respectively. Sex ratio during sampling showed that female fork-tailed threadfin bream greater than male population. Berried female fork-tailed threadfin bream found from March until November. The greatest number of berried female fork-tailed threadfin bream showed in July with berried female value of 25. Fork-tailed threadfin bream fecundity was 19951 and 66628, respectively. The fecundity data can be used to access the reproductive potential of fish stock and also as an assessment on stock size of their natural population.

  9. Characteristics of the tail of Comet Giacobini-Zinner

    NASA Technical Reports Server (NTRS)

    Scarf, F. L.

    1986-01-01

    The physical structure and characteristics of the Comet Giacobini-Zinner tail are described. Variations in the vector B-field configuration, the electron distribution function, the energetic ion population, and the electromagnetic and electrostatic plasma wave spectra are analyzed. The ICE detected a two-lobe magnetic field configuration and a narrow central plasma sheet. Additional analyses proposed for the Giacobini-Zinner tail data are discussed.

  10. Ferric minerals and organic matter change arsenic speciation in copper mine tailings.

    PubMed

    Wang, Peng; Liu, Yunjia; Menzies, Neal W; Wehr, J Bernhard; de Jonge, Martin D; Howard, Daryl L; Kopittke, Peter M; Huang, Longbin

    2016-11-01

    Arsenic (As) is commonly associated with Cu ore minerals, with the resultant risk that As can be released offsite from mine tailings. We used synchrotron-based fluorescence X-ray absorption near-edge spectroscopy (XANES) imaging to provide in situ, laterally-resolved speciation of As within tailings which differed in magnetite content (5-12%) and organic matter content (0-5%). Although the total As content was lower in tailings with low magnetite (LM), the soluble (pore water) As was actually 7-times higher in LM tailings than in high magnetite (HM) tailings. Additionally, amendment with 5% sugarcane mulch residues (SMR) (for revegetation) further increased soluble As due to the dissolution and oxidation of arsenopyrite or orpiment. Indeed, in HM tailings, arsenopyrite and orpiment initially accounted for 88% of the total As, which decreased to 48% upon the addition of SMR - this being associated with an increase in As V -ferrihydrite from 12% to 52%. In LM tailings, the pattern of As distribution and speciation was similar, with As as As V -ferrihydrite increasing from 57% to 75% upon the addition of SMR. These findings indicate that changes in ore processing technology, such as the recovery of magnetite could have significant environmental consequences regarding the As mobilisation and transformation in mine tailings. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Extremely High Phosphate Sorption Capacity in Cu-Pb-Zn Mine Tailings

    PubMed Central

    Huang, Longbin; Li, Xiaofang; Nguyen, Tuan A. H.

    2015-01-01

    Elevated inorganic phosphate (Pi) concentrations in pore water of amended tailings under direct revegetation may cause toxicity in some native woody species but not native forbs or herb species, all of which are key constituents in target native plant communities for phytostabilizing base metal mine tailings. As a result, Pi sorption capacity has been quantified by a conventional batch procedure in three types of base metal mine tailings sampled from two copper (Cu)-lead (Pb)-zinc (Zn) mines, as the basis for Pi-fertiliser addition. It was found that the Pi-sorption capacity in the tailings and local soil was extremely high, far higher than highly weathered agricultural soils in literature, but similar to those of volcanic ash soils. The Langmuir P-sorption maximum was up to 7.72, 4.12, 4.02 and 3.62 mg P g-1 tailings, in the fresh tailings of mixed Cu-Pb-Zn streams (MIMTD7), the weathered tailings of mixed Cu-Pb-Zn streams (MIMTD5), EHM-TD (fresh Cu-stream, high magnetite content) and local soil (weathered shale and schist), respectively. Physicochemical factors highly correlated with the high Pi-sorption in the tailings were fine particle distribution, oxalate and dithionite-citrate-bicarbonate extractable Fe (FeO and Fed), oxalate-extractable Al and Mn, and the levels of soluble Cd and Zn, and total S and Fe. Large amounts of amorphous Fe oxides and oxyhydroxides may have been formed from the oxidation of pyritic materials and redox cycles of Fe-minerals (such as pyrite (FeS2), ankerite (Ca(Fe Mg)(CO3)2 and siderite (FeCO3), as indicated by the extractable FeO values. The likely formation of sparingly soluble Zn-phosphate in the Pb-Zn tailings containing high levels of Zn (from sphalerite ((Zn,Fe)S, ZnS, (Zn,Cd)S)) may substantially lower soluble Zn levels in the tailings through high rates of Pi-fertiliser addition. As a result, the possibility of P-toxicity in native plant species caused by the addition of soluble phosphate fertilizers would be minimal. PMID

  12. Tail regeneration in Urodela: old model and new perspectives in studies

    NASA Astrophysics Data System (ADS)

    Grigoryan, E.; Anton, H.; Mitashov, V.

    For better understanding of micro-"g" effect on nervous tissue regeneration we have chosen the regeneration of the Urodele tail, because it utilizes many developmental processes and represents the most convenient model for experiments in Space. The special interesting aspect lies in the ability of regenerates to differentiate the spinal cord (SC) and this, in turn, has a potential of practical application. Meanwhile there are conclusive evidences suggesting the production by SC cells the neurotrophic factors promoting cell proliferation and differentiation in growing tail regenerate. Previously our studies on tail regeneration in the adult newt showed that the force of gravity clearly inf luences the events underlying the regeneration. We reported the significant increase of tail regeneration rate and tissue volume of tail regenerates in the newts exposed to real and simulated low "g". In Bion 11 mission animals that were exposed 14 days in microgravity and whose tails were operated two and four weeks before launch demonstrated the regenerates achieved 1.5 - 2 times the volume of those in 1"g" control. Results of this experiment indicated also that the regeneration of central and peripheral neurons and nerve fibers was carrying out faster under low "g" conditions than in 1 "g" control. Similar data were obtained in several experiments remodeling physiological weightlessness by mean of the clinostat. It led us to the hypothesis that the stimulation of tail regeneration is linked with an over activation of neurotrophic factors produced by quickly growing SC neurons. Now we've completed the experiment on tail regeneration in the newts Tr. alpestris subjected to 5 day long clinorotation after 6 days post tail amputation. The rate of primary- and secondary regeneration was evaluated at different time points after treatment. Cell proliferation, differentiation and expression of neurotrophic proteins in SC and other major tissue-type of regenerate were investigated by

  13. The Role of Histone Tails in the Nucleosome: A Computational Study

    PubMed Central

    Erler, Jochen; Zhang, Ruihan; Petridis, Loukas; Cheng, Xiaolin; Smith, Jeremy C.; Langowski, Jörg

    2014-01-01

    Histone tails play an important role in gene transcription and expression. We present here a systematic computational study of the role of histone tails in the nucleosome, using replica exchange molecular dynamics simulations with an implicit solvent model and different well-established force fields. We performed simulations for all four histone tails, H4, H3, H2A, and H2B, isolated and with inclusion of the nucleosome. The results confirm predictions of previous theoretical studies for the secondary structure of the isolated tails but show a strong dependence on the force field used. In the presence of the entire nucleosome for all force fields, the secondary structure of the histone tails is destabilized. Specific contacts are found between charged lysine and arginine residues and DNA phosphate groups and other binding sites in the minor and major DNA grooves. Using cluster analysis, we found a single dominant configuration of binding to DNA for the H4 and H2A histone tails, whereas H3 and H2B show multiple binding configurations with an equal probability. The leading stabilizing contribution for those binding configurations is the attractive interaction between the positively charged lysine and arginine residues and the negatively charged phosphate groups, and thus the resulting charge neutralization. Finally, we present results of molecular dynamics simulations in explicit solvent to confirm our conclusions. Results from both implicit and explicit solvent models show that large portions of the histone tails are not bound to DNA, supporting the complex role of these tails in gene transcription and expression and making them possible candidates for binding sites of transcription factors, enzymes, and other proteins. PMID:25517156

  14. Crystal Structure of Bacteriophage SPP1 Distal Tail Protein (gp19.1)

    PubMed Central

    Veesler, David; Robin, Gautier; Lichière, Julie; Auzat, Isabelle; Tavares, Paulo; Bron, Patrick; Campanacci, Valérie; Cambillau, Christian

    2010-01-01

    Siphophage SPP1 infects the Gram-positive bacterium Bacillus subtilis using its long non-contractile tail and tail-tip. Electron microscopy (EM) previously allowed a low resolution assignment of most orf products belonging to these regions. We report here the structure of the SPP1 distal tail protein (Dit, gp19.1). The combination of x-ray crystallography, EM, and light scattering established that Dit is a back-to-back dimer of hexamers. However, Dit fitting in the virion EM maps was only possible with a hexamer located between the tail-tube and the tail-tip. Structure comparison revealed high similarity between Dit and a central component of lactophage baseplates. Sequence similarity search expanded its relatedness to several phage proteins, suggesting that Dit is a docking platform for the tail adsorption apparatus in Siphoviridae infecting Gram-positive bacteria and that its architecture is a paradigm for these hub proteins. Dit structural similarity extends also to non-contractile and contractile phage tail proteins (gpVN and XkdM) as well as to components of the bacterial type 6 secretion system, supporting an evolutionary connection between all these devices. PMID:20843802

  15. Loss of intestinal GATA4 prevents diet-induced obesity and promotes insulin sensitivity in mice

    PubMed Central

    Patankar, Jay V.; Chandak, Prakash G.; Obrowsky, Sascha; Pfeifer, Thomas; Diwoky, Clemens; Uellen, Andreas; Sattler, Wolfgang; Stollberger, Rudolf; Hoefler, Gerald; Heinemann, Akos; Battle, Michele; Duncan, Stephen; Kratky, Dagmar

    2011-01-01

    Transcriptional regulation of small intestinal gene expression controls plasma total cholesterol (TC) and triglyceride (TG) levels, which are major determinants of metabolic diseases. GATA4, a zinc finger domain transcription factor, is critical for jejunal identity, and intestinal GATA4 deficiency leads to a jejunoileal transition. Although intestinal GATA4 ablation is known to misregulate jejunal gene expression, its pathophysiological impact on various components of metabolic syndrome remains unknown. Here, we used intestine-specific GATA4 knockout (GATA4iKO) mice to dissect the contribution of GATA4 on obesity development. We challenged adult GATA4iKO mice and control littermates with a Western-type diet (WTD) for 20 wk. Our findings show that WTD-fed GATA4iKO mice are resistant to diet-induced obesity. Accordingly, plasma TG and TC levels are markedly decreased. Intestinal lipid absorption in GATA4iKO mice was strongly reduced, whereas luminal lipolysis was unaffected. GATA4iKO mice displayed a greater glucagon-like peptide-1 (GLP-1) release on normal chow and even after long-term challenge with WTD remained glucose sensitive. In summary, our findings show that the absence of intestinal GATA4 has a beneficial effect on decreasing intestinal lipid absorption causing resistance to hyperlipidemia and obesity. In addition, we show that increased GLP-1 release in GATA4iKO mice decreases the risk for development of insulin resistance. PMID:21177287

  16. Environmental Risk Assessment System for Phosphogypsum Tailing Dams

    PubMed Central

    Sun, Xin; Tang, Xiaolong; Yi, Honghong; Li, Kai; Zhou, Lianbi; Xu, Xianmang

    2013-01-01

    This paper may be of particular interest to the readers as it provides a new environmental risk assessment system for phosphogypsum tailing dams. In this paper, we studied the phosphogypsum tailing dams which include characteristics of the pollution source, environmental risk characteristics and evaluation requirements to identify the applicable environmental risk assessment methods. Two analytical methods, that is, the analytic hierarchy process (AHP) and fuzzy logic, were used to handle the complexity of the environmental and nonquantitative data. Using our assessment method, different risk factors can be ranked according to their contributions to the environmental risk, thereby allowing the calculation of their relative priorities during decision making. Thus, environmental decision-makers can use this approach to develop alternative management strategies for proposed, ongoing, and completed PG tailing dams. PMID:24382947

  17. Environmental risk assessment system for phosphogypsum tailing dams.

    PubMed

    Sun, Xin; Ning, Ping; Tang, Xiaolong; Yi, Honghong; Li, Kai; Zhou, Lianbi; Xu, Xianmang

    2013-01-01

    This paper may be of particular interest to the readers as it provides a new environmental risk assessment system for phosphogypsum tailing dams. In this paper, we studied the phosphogypsum tailing dams which include characteristics of the pollution source, environmental risk characteristics and evaluation requirements to identify the applicable environmental risk assessment methods. Two analytical methods, that is, the analytic hierarchy process (AHP) and fuzzy logic, were used to handle the complexity of the environmental and nonquantitative data. Using our assessment method, different risk factors can be ranked according to their contributions to the environmental risk, thereby allowing the calculation of their relative priorities during decision making. Thus, environmental decision-makers can use this approach to develop alternative management strategies for proposed, ongoing, and completed PG tailing dams.

  18. Power-law tails in the distribution of order imbalance

    NASA Astrophysics Data System (ADS)

    Zhang, Ting; Gu, Gao-Feng; Xu, Hai-Chuan; Xiong, Xiong; Chen, Wei; Zhou, Wei-Xing

    2017-10-01

    We investigate the probability distribution of order imbalance calculated from the order flow data of 43 Chinese stocks traded on the Shenzhen Stock Exchange. Two definitions of order imbalance are considered based on the order number and the order size. We find that the order imbalance distributions of individual stocks have power-law tails. However, the tail index fluctuates remarkably from stock to stock. We also investigate the distributions of aggregated order imbalance of all stocks at different timescales Δt. We find no clear trend in the tail index with respect Δt. All the analyses suggest that the distributions of order imbalance are asymmetric.

  19. Effects of aerodynamic interaction between main and tail rotors on helicopter hover performance and noise

    NASA Technical Reports Server (NTRS)

    Menger, R. P.; Wood, T. L.; Brieger, J. T.

    1983-01-01

    A model test was conducted to determine the effects of aerodynamic interaction between main rotor, tail rotor, and vertical fin on helicopter performance and noise in hover out of ground effect. The experimental data were obtained from hover tests performed with a .151 scale Model 222 main rotor, tail rotor and vertical fin. Of primary interest was the effect of location of the tail rotor with respect to the main rotor. Penalties on main rotor power due to interaction with the tail rotor ranged up to 3% depending upon tail rotor location and orientation. Penalties on tail rotor power due to fin blockage alone ranged up to 10% for pusher tail rotors and up to 50% for tractor tail rotors. The main rotor wake had only a second order effect on these tail rotor/fin interactions. Design charts are presented showing the penalties on main rotor power as a function of the relative location of the tail rotor.

  20. Goal-directed tail use in Colombian spider monkeys (Ateles fusciceps rufiventris) is highly lateralized.

    PubMed

    Nelson, Eliza L; Kendall, Giulianna A

    2018-02-01

    Behavioral laterality refers to a bias in the use of one side of the body over the other and is commonly studied in paired organs (e.g., hands, feet, eyes, antennae). Less common are reports of laterality in unpaired organs (e.g., trunk, tongue, tail). The goal of the current study was to examine tail use biases across different tasks in the Colombian spider monkey ( Ateles fusciceps rufiventris ) for the first time (N = 14). We hypothesized that task context and task complexity influence tail laterality in spider monkeys, and we predicted that monkeys would exhibit strong preferences for using the tail for manipulation to solve out-of-reach feeding problems, but not for using the tail at rest. Our results show that a subset of spider monkeys solved each of the experimental problems through goal-directed tail use (N = 7). However, some tasks were more difficult than others, given the number of monkeys who solved the tasks. Our results supported our predictions regarding laterality in tail use and only partially replicated prior work on tail use preferences in Geoffroy's spider monkeys ( Ateles geoffroyi ). Overall, skilled tail use, but not resting tail use, was highly lateralized in Colombian spider monkeys. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  1. Modified binders on the basis of flotation tailings

    NASA Astrophysics Data System (ADS)

    Shapovalov, N. A.; Zagorodnyuk, L. Kh; Shchekina, A. Yu; Gorodov, A. I.

    2018-03-01

    The article proposes compositions of efficient modified composite binders on the basis of portland cement and flotation tailings; the new binders attain the ultimate compressive stress that is twice as high as that of the cement stone. At that, use of annually growing volume of flotation tailings in the production of the composite binder is a rational way for recycling this type of waste and allows saving the planet's natural resources.

  2. Testing tail-mounted transmitters with Myocastor coypus (nutria)

    USGS Publications Warehouse

    Merino, S.; Carter, J.; Thibodeaux, G.

    2007-01-01

    We developed a tail-mounted radio-transmitter for Myocastor coypus (nutria) that offers a practical and efficient alternative to collar or implant methods. The mean retention time was 96 d (range 57-147 d, n = 7), making this a practical method for short-term studies. The tail-mounts were less injurious to animals than collars and easier for field researchers to implement than either collars or surgically implanted transmitters.

  3. 14. Credit PED. Downstream elevation, near completion, showing tail race ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Credit PED. Downstream elevation, near completion, showing tail race and trestle used to carry excavated rock and construction materials across tail race. Photo c. 1909. - Dam No. 4 Hydroelectric Plant, Potomac River, Martinsburg, Berkeley County, WV

  4. Phytostabilization of Mine Tailings in Arid and Semiarid Environments—An Emerging Remediation Technology

    PubMed Central

    Mendez, Monica O.; Maier, Raina M.

    2008-01-01

    Objective Unreclaimed mine tailings sites are a worldwide problem, with thousands of unvegetated, exposed tailings piles presenting a source of contamination for nearby communities. Tailings disposal sites in arid and semiarid environments are especially subject to eolian dispersion and water erosion. Phytostabilization, the use of plants for in situ stabilization of tailings and metal contaminants, is a feasible alternative to costly remediation practices. In this review we emphasize considerations for phytostabilization of mine tailings in arid and semiarid environments, as well as issues impeding its long-term success. Data sources We reviewed literature addressing mine closures and revegetation of mine tailings, along with publications evaluating plant ecology, microbial ecology, and soil properties of mine tailings. Data extraction Data were extracted from peer-reviewed articles and books identified in Web of Science and Agricola databases, and publications available through the U.S. Department of Agriculture, U.S. Environmental Protection Agency, and the United Nations Environment Programme. Data synthesis Harsh climatic conditions in arid and semiarid environments along with the innate properties of mine tailings require specific considerations. Plants suitable for phytostabilization must be native, be drought-, salt-, and metal-tolerant, and should limit shoot metal accumulation. Factors for evaluating metal accumulation and toxicity issues are presented. Also reviewed are aspects of implementing phytostabilization, including plant growth stage, amendments, irrigation, and evaluation. Conclusions Phytostabilization of mine tailings is a promising remedial technology but requires further research to identify factors affecting its long-term success by expanding knowledge of suitable plant species and mine tailings chemistry in ongoing field trials. PMID:18335091

  5. Phytostabilization of mine tailings in arid and semiarid environments--an emerging remediation technology.

    PubMed

    Mendez, Monica O; Maier, Raina M

    2008-03-01

    Unreclaimed mine tailings sites are a worldwide problem, with thousands of unvegetated, exposed tailings piles presenting a source of contamination for nearby communities. Tailings disposal sites in arid and semiarid environments are especially subject to eolian dispersion and water erosion. Phytostabilization, the use of plants for in situ stabilization of tailings and metal contaminants, is a feasible alternative to costly remediation practices. In this review we emphasize considerations for phytostabilization of mine tailings in arid and semiarid environments, as well as issues impeding its long-term success. We reviewed literature addressing mine closures and revegetation of mine tailings, along with publications evaluating plant ecology, microbial ecology, and soil properties of mine tailings. Data were extracted from peer-reviewed articles and books identified in Web of Science and Agricola databases, and publications available through the U.S. Department of Agriculture, U.S. Environmental Protection Agency, and the United Nations Environment Programme. Harsh climatic conditions in arid and semiarid environments along with the innate properties of mine tailings require specific considerations. Plants suitable for phytostabilization must be native, be drought-, salt-, and metal-tolerant, and should limit shoot metal accumulation. Factors for evaluating metal accumulation and toxicity issues are presented. Also reviewed are aspects of implementing phytostabilization, including plant growth stage, amendments, irrigation, and evaluation. Phytostabilization of mine tailings is a promising remedial technology but requires further research to identify factors affecting its long-term success by expanding knowledge of suitable plant species and mine tailings chemistry in ongoing field trials.

  6. Review of the 2012 Epizootic Hemorrhagic Disease Outbreak in Domestic Ruminants in the United States

    PubMed Central

    Stevens, G.; McCluskey, B.; King, A.; O’Hearn, E.; Mayr, G.

    2015-01-01

    An unusually large number of cases of Epizootic hemorrhagic disease (EHD) were observed in United States cattle and white-tailed deer in the summer and fall of 2012. USDA APHIS Veterinary Services area offices were asked to report on foreign animal disease investigations and state diagnostic laboratory submissions which resulted in a diagnosis of EHD based on positive PCR results. EHD was reported in the following species: cattle (129 herds), captive white-tailed deer (65 herds), bison (8 herds), yak (6 herds), elk (1 herd), and sheep (1 flock). A majority of the cases in cattle and bison were found in Nebraska, South Dakota, and Iowa. The majority of cases in captive white-tailed deer were found in Ohio, Iowa, Michigan, and Missouri. The most common clinical sign observed in the cattle and bison herds was oral lesions. The major observation in captive white-tailed deer herds was death. Average within-herd morbidity was 7% in cattle and bison herds, and 46% in captive white-tailed deer herds. The average within-herd mortality in captive white-tailed deer herds was 42%. PMID:26244773

  7. Swallow-tailed kite nesting in Texas: Past and present

    Treesearch

    Raymond E. Brown; J. Howard Williamson; Dan B. Boone

    1997-01-01

    The historical breeding range of the swallow-tailed kite (Elanoides forficatus) in the United States extended from the Carolinas and Tennessee south through Florida, and Wisconsin and Minnesota south through louisiana, and Nebraska to central and southeastern Texas (Cely, 1979; Johnsgard,. 1990). By 1900, the range of the swallow-tailed kite was...

  8. Tail Docking and Ear Cropping Dogs: Public Awareness and Perceptions

    PubMed Central

    Mills, Katelyn E.; Robbins, Jesse; von Keyserlingk, Marina A. G.

    2016-01-01

    Tail docking and ear cropping are two surgical procedures commonly performed on many dog breeds. These procedures are classified as medically unnecessary surgeries whose purpose is primarily cosmetic. Available attitude research surrounding these controversial practices has been limited to surveys of veterinarians and dog breeders familiar with both practices. The aim of this project was to: 1) assess public awareness of tail docking and ear cropping, 2) determine whether physical alteration of a dog affects how the dog, and 3) owner are perceived. In Experiment 1 awareness was measured using a combination of both explicit and implicit measures. We found that 42% of participants (n = 810) were unable to correctly explain the reason why tail docked and ear cropped dogs had short ears and tails. Similarly, an implicit measure of awareness (‘nature vs nurture task’), found that the majority of participants believed short tails and erect ears were a consequence of genetics rather than something the owner or breeder had done. The results obtained in Experiment 2 (n = 392) provide evidence that ear cropped and tail docked dogs are perceived differently than an identical dog in its ‘natural’ state. Modified dogs were perceived as being more aggressive, more dominant, less playful and less attractive than natural dogs. Experiment 3 (n = 410) is the first evidence that owners of modified dogs are perceived as being more aggressive, more narcissistic, less playful, less talkative and less warm compared to owners of natural dogs. Taken together, these results suggest that although a significant proportion of subjects appear unaware of the practices of tail docking and ear cropping in dogs, these procedures have significant impacts on how modified dogs and their owners are perceived by others. PMID:27348817

  9. Is rhizosphere remediation sufficient for sustainable revegetation of mine tailings?

    PubMed

    Huang, Longbin; Baumgartl, Thomas; Mulligan, David

    2012-07-01

    Revegetation of mine tailings (fine-grained waste material) starts with the reconstruction of root zones, consisting of a rhizosphere horizon (mostly topsoil and/or amended tailings) and the support horizon beneath (i.e. equivalent to subsoil - mostly tailings), which must be physically and hydro-geochemically stable. This review aims to discuss key processes involved in the development of functional root zones within the context of direct revegetation of tailings and introduces a conceptual process of rehabilitating structure and function in the root zones based on a state transition model. Field studies on the revegetation of tailings (from processing base metal ore and bauxite residues) are reviewed. Particular focus is given to tailings' properties that limit remediation effectiveness. Aspects of root zone reconstruction and vegetation responses are also discussed. When reconstructing a root zone system, it is critical to restore physical structure and hydraulic functions across the whole root zone system. Only effective and holistically restored systems can control hydro-geochemical mobility of acutely and chronically toxic factors from the underlying horizon and maintain hydro-geochemical stability in the rhizosphere. Thereafter, soil biological capacity and ecological linkages (i.e. carbon and nutrient cycling) may be rehabilitated to integrate the root zones with revegetated plant communities into sustainable plant ecosystems. A conceptual framework of system transitions between the critical states of root zone development has been proposed. This will illustrate the rehabilitation process in root zone reconstruction and development for direct revegetation with sustainable plant communities. Sustainable phytostabilization of tailings requires the systematic consideration of hydro-geochemical interactions between the rhizosphere and the underlying supporting horizon. It further requires effective remediation strategies to develop hydro-geochemically stable

  10. Tail Docking and Ear Cropping Dogs: Public Awareness and Perceptions.

    PubMed

    Mills, Katelyn E; Robbins, Jesse; von Keyserlingk, Marina A G

    2016-01-01

    Tail docking and ear cropping are two surgical procedures commonly performed on many dog breeds. These procedures are classified as medically unnecessary surgeries whose purpose is primarily cosmetic. Available attitude research surrounding these controversial practices has been limited to surveys of veterinarians and dog breeders familiar with both practices. The aim of this project was to: 1) assess public awareness of tail docking and ear cropping, 2) determine whether physical alteration of a dog affects how the dog, and 3) owner are perceived. In Experiment 1 awareness was measured using a combination of both explicit and implicit measures. We found that 42% of participants (n = 810) were unable to correctly explain the reason why tail docked and ear cropped dogs had short ears and tails. Similarly, an implicit measure of awareness ('nature vs nurture task'), found that the majority of participants believed short tails and erect ears were a consequence of genetics rather than something the owner or breeder had done. The results obtained in Experiment 2 (n = 392) provide evidence that ear cropped and tail docked dogs are perceived differently than an identical dog in its 'natural' state. Modified dogs were perceived as being more aggressive, more dominant, less playful and less attractive than natural dogs. Experiment 3 (n = 410) is the first evidence that owners of modified dogs are perceived as being more aggressive, more narcissistic, less playful, less talkative and less warm compared to owners of natural dogs. Taken together, these results suggest that although a significant proportion of subjects appear unaware of the practices of tail docking and ear cropping in dogs, these procedures have significant impacts on how modified dogs and their owners are perceived by others.

  11. Is rhizosphere remediation sufficient for sustainable revegetation of mine tailings?

    PubMed Central

    Huang, Longbin; Baumgartl, Thomas; Mulligan, David

    2012-01-01

    Background Revegetation of mine tailings (fine-grained waste material) starts with the reconstruction of root zones, consisting of a rhizosphere horizon (mostly topsoil and/or amended tailings) and the support horizon beneath (i.e. equivalent to subsoil – mostly tailings), which must be physically and hydro-geochemically stable. This review aims to discuss key processes involved in the development of functional root zones within the context of direct revegetation of tailings and introduces a conceptual process of rehabilitating structure and function in the root zones based on a state transition model. Scope Field studies on the revegetation of tailings (from processing base metal ore and bauxite residues) are reviewed. Particular focus is given to tailings' properties that limit remediation effectiveness. Aspects of root zone reconstruction and vegetation responses are also discussed. Conclusions When reconstructing a root zone system, it is critical to restore physical structure and hydraulic functions across the whole root zone system. Only effective and holistically restored systems can control hydro-geochemical mobility of acutely and chronically toxic factors from the underlying horizon and maintain hydro-geochemical stability in the rhizosphere. Thereafter, soil biological capacity and ecological linkages (i.e. carbon and nutrient cycling) may be rehabilitated to integrate the root zones with revegetated plant communities into sustainable plant ecosystems. A conceptual framework of system transitions between the critical states of root zone development has been proposed. This will illustrate the rehabilitation process in root zone reconstruction and development for direct revegetation with sustainable plant communities. Sustainable phytostabilization of tailings requires the systematic consideration of hydro-geochemical interactions between the rhizosphere and the underlying supporting horizon. It further requires effective remediation strategies to

  12. Effect of Dynamic Rolling Oscillations on Twin Tail Buffet Response

    NASA Technical Reports Server (NTRS)

    Sheta, Essam F.; Kandil, Osama A.

    1999-01-01

    The effect of dynamic rolling oscillations of delta-wing/twin-tail configuration on twin-tail buffet response is investigated. The computational model consists of a sharp-edged delta wing of aspect ratio one and swept-back flexible twin tail with taper ratio of 0.23. The configuration model is statically pitched at 30 deg. angle of attack and then forced to oscillate in roll around the symmetry axis at a constant amplitude of 4 deg. and reduced frequency of pi and 2(pi). The freestream Mach number and Reynolds number are 0.3 and 1.25 million, respectively. This multidisciplinary problem is solved using three sets of equations on a dynamic multi-block grid structure. The first set is the unsteady, full Navier-Stokes equations, the second set is the aeroelastic equations for coupled bending and torsion vibrations of the tails, and the third set is the grid-displacement equations. The configuration is investigated for inboard position of the twin tails which corresponds to a separation distance between the twin tails of 33% wing span. The computed results are compared with the results of stationary configuration, which previously have been validated using experimental data. The results conclusively showed that the rolling oscillations of the configuration have led to higher loads, higher deflections, and higher excitation peaks than those of the stationary configuration. Moreover, increasing the reduced frequency has led to higher loads and excitation peaks and lower bending and torsion deflections and acceleration.

  13. Endosonography and cytology in diagnosing and staging pancreatic body and tail carcinoma: Preliminary results of endosonographic guided puncture

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tio, T.L.; Sie, L.H.; Tytgat, G.N.J.

    1993-01-01

    Endosonography was performed in diagnosing and staging pancreatic body and tail carcinoma in two patients. In the first case endoscopy, abdominal ultrasound, and computed tomography were nondiagnostic in diagnosing the origin of submucosal gastric abnormalities. Endosonography diagnosed a pancreatic tail carcinoma with submucosal gastric involvement, and this was confirmed by endosonographic-guided cytology. Fundus varices due to segmented splenic vein involvement were found. Surgery was not recommended due to the advanced disease. In the second case pancreatic body carcinoma was diagnosed by ERCP and computed tomography. Transcutaneous ultrasonographic-guided cytological puncture confirmed the diagnosis. Endosonography revealed additional information of segmental portal hypertensionmore » with fundic varices due to splenic vein involvement. Autopsy confirmed the endosonographic diagnosis. 18 refs., 5 figs.« less

  14. On the statistical properties and tail risk of violent conflicts

    NASA Astrophysics Data System (ADS)

    Cirillo, Pasquale; Taleb, Nassim Nicholas

    2016-06-01

    We examine statistical pictures of violent conflicts over the last 2000 years, providing techniques for dealing with the unreliability of historical data. We make use of a novel approach to deal with fat-tailed random variables with a remote but nonetheless finite upper bound, by defining a corresponding unbounded dual distribution (given that potential war casualties are bounded by the world population). This approach can also be applied to other fields of science where power laws play a role in modeling, like geology, hydrology, statistical physics and finance. We apply methods from extreme value theory on the dual distribution and derive its tail properties. The dual method allows us to calculate the real tail mean of war casualties, which proves to be considerably larger than the corresponding sample mean for large thresholds, meaning severe underestimation of the tail risks of conflicts from naive observation. We analyze the robustness of our results to errors in historical reports. We study inter-arrival times between tail events and find that no particular trend can be asserted. All the statistical pictures obtained are at variance with the prevailing claims about ;long peace;, namely that violence has been declining over time.

  15. OVERVIEW OF CYANIDE PLANT REMAINS, TAILINGS PILES, PARKING LOT, AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    OVERVIEW OF CYANIDE PLANT REMAINS, TAILINGS PILES, PARKING LOT, AND MINE MANAGER'S HOME, LOOKING SOUTH SOUTHEAST. RIGHT, TAILINGS PILES ARE AT CENTER WITH CYANIDE PLANT FOUNDATIONS TO THE LEFT OF THE PILES. PARKING LOT IS AT UPPER LEFT. THE AREA BETWEEN THE COLLAPSED TANK AT CENTER LEFT AND THE REMAINS OF THE MANAGER'S HOUSE AT LOWER RIGHT IS A TAILINGS HOLDING AREA. TAILINGS FROM THE MILL WERE HELD HERE. THE LARGE SETTLING TANKS WERE CHARGED FROM THIS HOLDING AREA BY A TRAM ON RAILS AND BY A SLUICEWAY SEEN AS THE DARK SPOT ON THE CENTER LEFT EDGE OF THE FRAME. AFTER THE TAILINGS WERE LEACHED, THEY WERE DEPOSITED ON THE LARGE WASTE PILE AT CENTER RIGHT. THE TANK AT CENTER RIGHT EDGE IS WHERE THE WATER PIPELINE ENTERED THE WORKS. A STRAIGHT LINE OF POSTS IN THE GROUND GO ACROSS THE CENTER FROM LEFT TO RIGHT, WHICH ORIGINALLY SUSPENDED THE WATER PIPELINE GOING FROM THE WATER HOLDING TANK AT RIGHT UP TO THE SECONDARY WATER TANKS ABOVE THE MILL. - Keane Wonder Mine, Park Route 4 (Daylight Pass Cutoff), Death Valley Junction, Inyo County, CA

  16. Removal of heavy metals from Missouri lead mill tailings by froth flotation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Benn, F.W.; Cornell, W.L.

    Froth flotation techniques to remove heavy metals (Pb, Cu, and Zn) from southeast Missouri lead mill tailings were investigated. It has been estimated that southeast Missouri contains between 200 and 300 million st of Pb tailings stored above ground. The tailings were classified as two distinct types: (1) pre-1968 tailings from the Old Lead Belt (some more than 100 years old) and (2) post-1968 tailings from the New Lead Belt. The objectives of the investigation were to reduce the Pb remaining in the tailings to < 500 ppm (< 0.05 pct Pb) and to attempt to recover a marketable concentratemore » to offset a portion of the remediation costs. The remaining dolomite-limestone would then be used as mining backfill or agricultural limestone. Bench-scale froth flotation removed, in percent, 95 Pb, 84 Cu, and 54 Zn, leaving 94 pct of the original weight containing, in parts per million, 400 Pb, 40 Cu, and 300 Zn from the Old Lead Belt tailings. Separate flotation tests also removed, in percent, 85 Pb, 84 Cu, and 80 Zn, leaving 75 pct of the original weight containing, in parts per million, 400 Pb, 200 Cu, and 500 Zn from the New Lead Belt tailings. Concentrates recovered from the Old Lead Belt were retreated to produce a final Pb concentrate containing 72 pct Pb with a cleaner flotation recovery of 79 pct. Froth flotation proved to be a viable method to remove the heavy metals.« less

  17. Supersonic aerodynamic characteristics of a low-aspect-ratio missile model with wing and tail controls and with tails in line and interdigitated

    NASA Technical Reports Server (NTRS)

    Graves, E. B.

    1972-01-01

    A study has been made to determine the aerodynamic characteristics of a low-aspect ratio cruciform missile model with all-movable wings and tails. The configuration was tested at Mach numbers from 1.50 to 4.63 with the wings in the vertical and horizontal planes and with the wings in a 45 deg roll plane with tails in line and interdigitated.

  18. Chronic Wasting Disease Prions in Elk Antler Velvet

    USDA-ARS?s Scientific Manuscript database

    Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy or prion disease of captive and free ranging white tailed deer, mule deer, Rocky Mountain elk and moose in the some parts of the United States and Canada. The presence of the disease has sharply curtailed movement of captive...

  19. Vitally important: The role of demography in assessing the current and future status of black-tailed prairie dogs

    Treesearch

    Aaron Neil Facka

    2006-01-01

    Black-tailed prairie dogs have declined across their range by an estimated 98% in the last 100 years as the result of habitat loss, disease and human persecution. Commonly regarded as a keystone species, they represent a unique conservation dilemma because of their importance to other species, (e.g. the black-footed ferret- Mustela nigripes), while having the general...

  20. Windblown Dust Deposition Forecasting and Spread of Contamination around Mine Tailings.

    PubMed

    Stovern, Michael; Guzmán, Héctor; Rine, Kyle P; Felix, Omar; King, Matthew; Ela, Wendell P; Betterton, Eric A; Sáez, Avelino Eduardo

    2016-02-01

    Wind erosion, transport and deposition of windblown dust from anthropogenic sources, such as mine tailings impoundments, can have significant effects on the surrounding environment. The lack of vegetation and the vertical protrusion of the mine tailings above the neighboring terrain make the tailings susceptible to wind erosion. Modeling the erosion, transport and deposition of particulate matter from mine tailings is a challenge for many reasons, including heterogeneity of the soil surface, vegetative canopy coverage, dynamic meteorological conditions and topographic influences. In this work, a previously developed Deposition Forecasting Model (DFM) that is specifically designed to model the transport of particulate matter from mine tailings impoundments is verified using dust collection and topsoil measurements. The DFM is initialized using data from an operational Weather Research and Forecasting (WRF) model. The forecast deposition patterns are compared to dust collected by inverted-disc samplers and determined through gravimetric, chemical composition and lead isotopic analysis. The DFM is capable of predicting dust deposition patterns from the tailings impoundment to the surrounding area. The methodology and approach employed in this work can be generalized to other contaminated sites from which dust transport to the local environment can be assessed as a potential route for human exposure.

  1. Windblown Dust Deposition Forecasting and Spread of Contamination around Mine Tailings

    PubMed Central

    Stovern, Michael; Guzmán, Héctor; Rine, Kyle P.; Felix, Omar; King, Matthew; Ela, Wendell P.; Betterton, Eric A.; Sáez, Avelino Eduardo

    2017-01-01

    Wind erosion, transport and deposition of windblown dust from anthropogenic sources, such as mine tailings impoundments, can have significant effects on the surrounding environment. The lack of vegetation and the vertical protrusion of the mine tailings above the neighboring terrain make the tailings susceptible to wind erosion. Modeling the erosion, transport and deposition of particulate matter from mine tailings is a challenge for many reasons, including heterogeneity of the soil surface, vegetative canopy coverage, dynamic meteorological conditions and topographic influences. In this work, a previously developed Deposition Forecasting Model (DFM) that is specifically designed to model the transport of particulate matter from mine tailings impoundments is verified using dust collection and topsoil measurements. The DFM is initialized using data from an operational Weather Research and Forecasting (WRF) model. The forecast deposition patterns are compared to dust collected by inverted-disc samplers and determined through gravimetric, chemical composition and lead isotopic analysis. The DFM is capable of predicting dust deposition patterns from the tailings impoundment to the surrounding area. The methodology and approach employed in this work can be generalized to other contaminated sites from which dust transport to the local environment can be assessed as a potential route for human exposure. PMID:29082035

  2. Application of three tailing-based composites in treating comprehensive electroplating wastewater.

    PubMed

    Liu, Hongbo; Zhu, Mengling; Gao, Saisai

    2014-01-01

    Heavy metals and chemical oxygen demand (COD) are major challenging pollutants for most electroplating wastewater treatment plants. A novel composite material, prepared with a mixture of calcium and sodium compounds and tailings, was simply mixed by ratios and used to treat a comprehensive electroplating wastewater with influent COD, total copper (T-Cu), and total nickel (T-Ni) respectively as 690, 4.01, and 20.60 mg/L on average. Operational parameters, i.e. the contact time, pH, mass ratio of calcium and sodium compounds and tailings, were optimized as 30 min, 10.0, and 4:2:1. Removal rates for COD, T-Cu, and T-Ni could reach 71.8, 90.5, and 98.1%, respectively. No significant effect of initial concentrations on removal of T-Cu and T-Ni was observed for the composite material. The adsorption of Cu(II) and Ni(II) on the material fitted Langmuir and Freundlich isotherms respectively. Weight of waste sludge from the calcium/sodium-tailing system after reaction was 10% less than that from the calcium-tailing system. The tailing-based composite is cost-effective in combating comprehensive electroplating pollution, which shows a possibility of applying the tailings in treating electroplating wastewater.

  3. The generation of magnetic fields and electric currents in cometary plasma tails

    NASA Technical Reports Server (NTRS)

    Ip, W.-H.; Mendis, D. A.

    1976-01-01

    Due to the folding of the interplanetary magnetic field into the tail as a comet sweeps through the interplanetary medium, the magnetic field in the tail can be built up to the order of 100 gammas at a heliocentric distance of about 1 AU. This folding of magnetic flux tubes also results in a cross-tail electric current passing through a neutral sheet. When streams of enhanced plasma density merge with the main tail, cross-tail currents as large as 1 billion A may result. A condition could arise which causes a significant fraction of this current to be discharged through the inner coma, resulting in rapid ionization. The typical time scale for such outbursts of ionization is estimated to be of the order of 10,000 sec, which is in reasonable agreement with observation.

  4. Engineering assessment of inactive uranium mill tailings: Maybell Site, Maybell, Colorado. Summary

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1981-09-01

    Ford, Bacon and Davis Utah Inc. has reevaluated the Maybell site in order to revise the October 1977 engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at Maybell, Colorado. This engineering assessment has included the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and radiation exposures of individuals and nearby populations, the investigations of site hydrology and meteorology, and the evaluation and costing of alternative corrective actions. Radon gas released from the 2.6 million dry tons of tailings at the Maybell sitemore » constitutes the most significant environmental impact, although windblown tailings and external gamma radiation also are factors. The two alternative actions presented in this engineering assessment range from millsite decontamination with the addition of 3 m of stabilization cover material (Option I), to disposal of the tailings in a nearby open pit mine and decontamination of the tailings site (Option II). Cost estimates for the two options are about $11,700,000 for stabilization in-place and about $22,700,000 for disposal within a distance of 2 mi. Three principal alternatives for the reprocessing of the Maybell tailings were examined: (a) heap leaching; (b) treatment at an existing mill; and (c) reprocessing at a new conventional mill constructed for tailings reprocessing. The cost of the uranium recovered would be about $125 and $165/lb of U/sub 3/O/sub 8/ by heap leach and conventional plant processes, respectively. The spot market price for uranium was $25/lb early in 1981. Therefore, reprocessing the tailings for uranium recovery is not economically attractive at present.« less

  5. Scour of chinook salmon redds on suction dredge tailings

    Treesearch

    Bret C. Harvey; Thomas E. Lisle

    1999-01-01

    Abstract - We measured scour of the redds of chinook salmon Oncorhynchus tshawytscha on dredge tailings and natural substrates in three tributaries of the Klamath River, California. We measured maximum scour with scour chains and net scour by surveying before and after high winter flows. Scour of chinook salmon redds located on dredge tailings exceeded scour of redds...

  6. Tail function during arboreal quadrupedalism in squirrel monkeys (Saimiri boliviensis) and tamarins (Saguinus oedipus).

    PubMed

    Young, Jesse W; Russo, Gabrielle A; Fellmann, Connie D; Thatikunta, Meena A; Chadwell, Brad A

    2015-10-01

    The need to maintain stability on narrow branches is often presented as a major selective force shaping primate morphology, with adaptations to facilitate grasping receiving particular attention. The functional importance of a long and mobile tail for maintaining arboreal stability has been comparatively understudied. Tails can facilitate arboreal balance by acting as either static counterbalances or dynamic inertial appendages able to modulate whole-body angular momentum. We investigate associations between tail use and inferred grasping ability in two closely related cebid platyrrhines-cotton-top tamarins (Saguinus oedipus) and black-capped squirrel monkeys (Saimiri boliviensis). Using high-speed videography of captive monkeys moving on 3.2 cm diameter poles, we specifically test the hypothesis that squirrel monkeys (characterized by grasping extremities with long digits) will be less dependent on the tail for balance than tamarins (characterized by claw-like nails, short digits, and a reduced hallux). Tamarins have relatively longer tails than squirrel monkeys, move their tails through greater angular amplitudes, at higher angular velocities, and with greater angular accelerations, suggesting dynamic use of tail to regulate whole-body angular momentum. By contrast, squirrel monkeys generally hold their tails in a comparatively stationary posture and at more depressed angles, suggesting a static counterbalancing mechanism. This study, the first empirical test of functional tradeoffs between grasping ability and tail use in arboreal primates, suggests a critical role for the tail in maintaining stability during arboreal quadrupedalism. Our findings have the potential to inform our functional understanding of tail loss during primate evolution. © 2015 Wiley Periodicals, Inc.

  7. Release behavior of uranium in uranium mill tailings under environmental conditions.

    PubMed

    Liu, Bo; Peng, Tongjiang; Sun, Hongjuan; Yue, Huanjuan

    2017-05-01

    Uranium contamination is observed in sedimentary geochemical environments, but the geochemical and mineralogical processes that control uranium release from sediment are not fully appreciated. Identification of how sediments and water influence the release and migration of uranium is critical to improve the prevention of uranium contamination in soil and groundwater. To understand the process of uranium release and migration from uranium mill tailings under water chemistry conditions, uranium mill tailing samples from northwest China were investigated with batch leaching experiments. Results showed that water played an important role in uranium release from the tailing minerals. The uranium release was clearly influenced by contact time, liquid-solid ratio, particle size, and pH under water chemistry conditions. Longer contact time, higher liquid content, and extreme pH were all not conducive to the stabilization of uranium and accelerated the uranium release from the tailing mineral to the solution. The values of pH were found to significantly influence the extent and mechanisms of uranium release from minerals to water. Uranium release was monitored by a number of interactive processes, including dissolution of uranium-bearing minerals, uranium desorption from mineral surfaces, and formation of aqueous uranium complexes. Considering the impact of contact time, liquid-solid ratio, particle size, and pH on uranium release from uranium mill tailings, reducing the water content, decreasing the porosity of tailing dumps and controlling the pH of tailings were the key factors for prevention and management of environmental pollution in areas near uranium mines. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Characterization of Emergent Data Networks Among Long-Tail Data

    NASA Astrophysics Data System (ADS)

    Elag, Mostafa; Kumar, Praveen; Hedstrom, Margaret; Myers, James; Plale, Beth; Marini, Luigi; McDonald, Robert

    2014-05-01

    Data curation underpins data-driven scientific advancements. It manages the information flux across multiple users throughout data life cycle as well as increases data sustainability and reusability. The exponential growth in data production spanning across the Earth Science involving individual and small research groups, which is termed as log-tail data, increases the data-knowledge latency among related domains. It has become clear that an advanced framework-agnostic metadata and ontologies for long-tail data is required to increase their visibility to each other, and provide concise and meaningful descriptions that reveal their connectivity. Despite the advancement that has been achieved by various sophisticated data management models in different Earth Science disciplines, it is not always straightforward to derive relationships among long-tail data. Semantic data clustering algorithms and pre-defined logic rules that are oriented toward prediction of possible data relationships, is one method to address these challenges. Our work advances the connectivity of related long-tail data by introducing the design for an ontology-based knowledge management system. In this work, we present the system architecture, its components, and illustrate how it can be used to scrutinize the connectivity among datasets. To demonstrate the capabilities of this "data network" prototype, we implemented this approach within the Sustainable Environment Actionable Data (SEAD) environment, an open-source semantic content repository that provides a RDF database for long-tail data, and show how emergent relationships among datasets can be identified.

  9. Diagnostic Simulations of the Lunar Exosphere using Coma and Tail

    NASA Astrophysics Data System (ADS)

    Lee, Dong Wook; Kim, Sang J.

    2017-10-01

    The characteristics of the lunar exosphere can be constrained by comparing simulated models with observational data of the coma and tail (Lee et al., JGR, 2011); and thus far a few independent approaches on this issue have been performed and presented in the literature. Since there are two-different observational constraints for the lunar exosphere, it is interesting to find the best exospheric model that can account for the observed characteristics of the coma and tail. Considering various initial conditions of different sources and space weather, we present preliminary time-dependent simulations between the initial and final stages of the development of the lunar tail. Based on an updated 3-D model, we are planning to conduct numerous simulations to constrain the best model parameters from the coma images obtained from coronagraph observations supported by a NASA monitoring program (Morgan, Killen, and Potter, AGU, 2015) and future tail data.

  10. White-tailed deer in the Midwest.

    Treesearch

    USDA FS

    1970-01-01

    Discusses the present status and future prospects of the nonyarding white-tailed deer population in the Midwestern United States. Range appraisal, habitat, harvest regulation, and population control are included.

  11. Speciation and characterization of arsenic in Ketza River mine tailings using X-ray absorption spectroscopy.

    PubMed

    Paktunc, Dogan; Foster, Andrea; Laflamme, Gilles

    2003-05-15

    Ketza River mine tailings deposited underwater and those exposed near the tailings impoundment contain approximately 4 wt % As. Column-leaching tests indicated the potential for high As releases from the tailings. The tailings are composed dominantly of iron oxyhydroxides, quartz, calcite, dolomite, muscovite, ferric arsenates, and calcium-iron arsenates. Arsenopyrite and pyrite are trace constituents. Chemical compositions of iron oxyhydroxide and arsenate minerals are highly variable. The XANES spectra indicate that arsenic occurs as As(V) in tailings, but air-drying prior to analysis may have oxidized lower-valent As. The EXAFS spectra indicate As-Fe distances of 3.35-3.36 A for the exposed tailings and 3.33-3.35 A for the saturated tailings with coordination numbers of 0.96-1.11 and 0.46-0.64, respectively. The As-Ca interatomic distances ranging from 4.15 to 4.18 A and the coordination numbers of 4.12-4.58 confirm the presence of calcium-iron arsenates in the tailings. These results suggest that ferric arsenates and inner-sphere corner sharing or bidentate-binuclear attachment of arsenate tetrahedra onto iron hydroxide octahedra are the dominant form of As in the tailings. EXAFS spectra indicate that the exposed tailings are richer in arsenate minerals whereas the saturated tailings are dominated by the iron oxyhydroxides, which could help explain the greater release of As from the exposed tailings during leaching tests. It is postulated that the dissolution of ferric arsenates during flow-through experiments caused the high As releases from both types of tailings. Arsenic tied to iron oxyhydroxides as adsorbed species are considered stable; however, iron oxyhydroxides having low Fe/As molar ratios may not be as stable. Continued As releases from the tailings are likely due to dissolution of both ferric and calcium-iron arsenates and desorption of As from high-As bearing iron oxyhydroxides during aging.

  12. Speciation and characterization of arsenic in Ketza River mine tailings using x-ray absorption spectroscopy

    USGS Publications Warehouse

    Paktunc, D.; Foster, A.; Laflamme, G.

    2003-01-01

    Ketza River mine tailings deposited underwater and those exposed near the tailings impoundment contain approximately 4 wt % As. Column-leaching tests indicated the potential for high As releases from the tailings. The tailings are composed dominantly of iron oxyhydroxides, quartz, calcite, dolomite, muscovite, ferric arsenates, and calcium-iron arsenates. Arsenopyrite and pyrite are trace constituents. Chemical compositions of iron oxyhydroxide and arsenate minerals are highly variable. The XANES spectra indicate that arsenic occurs as As(V) in tailings, but air-drying prior to analysis may have oxidized lower-valent As. The EXAFS spectra indicate As-Fe distances of 3.35-3.36 A?? for the exposed tailings and 3.33-3.35 A?? for the saturated tailings with coordination numbers of 0.96-1.11 and 0.46-0.64, respectively. The As-Ca interatomic distances ranging from 4.15 to 4.18 A?? and the coordination numbers of 4.12-4.58 confirm the presence of calcium-iron arsenates in the tailings. These results suggest that ferric arsenates and inner-sphere corner sharing or bidentatebinuclear attachment of arsenate tetrahedra onto iron hydroxide octahedra are the dominant form of As in the tailings. EXAFS spectra indicate that the exposed tailings are richer in arsenate minerals whereas the saturated tailings are dominated by the iron oxyhydroxides, which could help explain the greater release of As from the exposed tailings during leaching tests. It is postulated that the dissolution of ferric arsenates during flow-through experiments caused the high As releases from both types of tailings. Arsenic tied to iron oxyhydroxides as adsorbed species are considered stable; however, iron oxyhydroxides having low Fe/As molar ratios may not be as stable. Continued As releases from the tailings are likely due to dissolution of both ferric and calcium-iron arsenates and desorption of As from high-As bearing iron oxyhydroxides during aging.

  13. The Tail-Elicited Tail Withdrawal Reflex of "Aplysia" Is Mediated Centrally at Tail Sensory-Motor Synapses and Exhibits Sensitization across Multiple Temporal Domains

    ERIC Educational Resources Information Center

    Philips, Gary T.; Sherff, Carolyn M.; Menges, Steven A.; Carew, Thomas J.

    2011-01-01

    The defensive withdrawal reflexes of "Aplysia californica" have provided powerful behavioral systems for studying the cellular and molecular basis of memory formation. Among these reflexes the (T-TWR) has been especially useful. In vitro studies examining the monosynaptic circuit for the T-TWR, the tail sensory-motor (SN-MN) synapses, have…

  14. Experimental oral transmission of chronic wasting disease to reindeer (Rangifer tarandus tarandus)

    USDA-ARS?s Scientific Manuscript database

    Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy or TSE of wild and farmed cervid ruminants in the North America, including white tailed, black tailed and mule deer, Rocky Mountain elk and Shira's moose. CWD, like the other TSEs, is associated with accumulation of an abnorm...

  15. Ulysses feels the brush of a comet's tail

    NASA Astrophysics Data System (ADS)

    2000-04-01

    "Ulysses's prime task is to map the solar wind above the Sun's poles: it had not been looking for Hyakutake, which happened to be at its closest approach to the Sun on 1 May 1996, or any other comet", says Richard Marsden, ESA's Ulysses Project Scientist. "Ulysses was just in the right place at the right time." The two teams stumbled across the telltale signature of a comet quite independently when poring over old Ulysses data. Jones and colleagues found their evidence in magnetic field data: "the magnetic field lines were draped in a way that you'd expect in a comet's tail," says Jones. The other instrument team, lead by George Gloeckler from the University of Maryland, found their evidence when looking at the composition of the solar wind. Cometary tails are rich in oxygen and carbon compared with the solar wind, but depleted in nitrogen and neon. The Imperial College team identified Hyakutake as the source of the anomalous readings. On 1 May 1996, Ulysses was aligned with the Sun and the position Hyakutake had occupied eight days earlier, which Jones calculated was the time needed for material leaving the comet's nucleus to travel the distance to Ulysses. One of the most surprising aspects of the discovery is the length of Hyakutake's tail. Cometary experts had thought that comet tails eventually spread out and lose their integrity. "We found that the whole thing is preserved as an entity and doesn't spread out very much," says Gloeckler. "If it can persist as far as Ulysses, there's no reason to presume that it wouldn't continue to the edge of the heliosphere (the boundary about 100AU from the Sun between the solar wind and the interstellar medium)," says Jones. "This discovery makes us wonder whether Ulysses or other spacecraft have crossed a comet tail before. So we're going back to look again for other signatures. But it's probably a rare event," says Jones. The comet nucleus has to be in exactly the right position with respect to the Sun and the spacecraft

  16. The fish tail motion forms an attached leading edge vortex

    PubMed Central

    Borazjani, Iman; Daghooghi, Mohsen

    2013-01-01

    The tail (caudal fin) is one of the most prominent characteristics of fishes, and the analysis of the flow pattern it creates is fundamental to understanding how its motion generates locomotor forces. A mechanism that is known to greatly enhance locomotor forces in insect and bird flight is the leading edge vortex (LEV) reattachment, i.e. a vortex (separation bubble) that stays attached at the leading edge of a wing. However, this mechanism has not been reported in fish-like swimming probably owing to the overemphasis on the trailing wake, and the fact that the flow does not separate along the body of undulating swimmers. We provide, to our knowledge, the first evidence of the vortex reattachment at the leading edge of the fish tail using three-dimensional high-resolution numerical simulations of self-propelled virtual swimmers with different tail shapes. We show that at Strouhal numbers (a measure of lateral velocity to the axial velocity) at which most fish swim in nature (approx. 0.25) an attached LEV is formed, whereas at a higher Strouhal number of approximately 0.6 the LEV does not reattach. We show that the evolution of the LEV drastically alters the pressure distribution on the tail and the force it generates. We also show that the tail's delta shape is not necessary for the LEV reattachment and fish-like kinematics is capable of stabilising the LEV. Our results suggest the need for a paradigm shift in fish-like swimming research to turn the focus from the trailing edge to the leading edge of the tail. PMID:23407826

  17. Application of a life cycle assessment to compare environmental performance in coal mine tailings management.

    PubMed

    Adiansyah, Joni Safaat; Haque, Nawshad; Rosano, Michele; Biswas, Wahidul

    2017-09-01

    This study compares coal mine tailings management strategies using life cycle assessment (LCA) and land-use area metrics methods. Hybrid methods (the Australian indicator set and the ReCiPe method) were used to assess the environmental impacts of tailings management strategies. Several strategies were considered: belt filter press (OPT 1), tailings paste (OPT 2), thickened tailings (OPT 3), and variations of OPT 1 using combinations of technology improvement and renewable energy sources (OPT 1A-D). Electrical energy was found to contribute more than 90% of the environmental impacts. The magnitude of land-use impacts associated with OPT 3 (thickened tailings) were 2.3 and 1.55 times higher than OPT 1 (tailings cake) and OPT 2 (tailings paste) respectively, while OPT 1B (tailings belt filter press with technology improvement and solar energy) and 1D (tailings belt press filter with technology improvement and wind energy) had the lowest ratio of environmental impact to land-use. Further analysis of an economic cost model and reuse opportunities is required to aid decision making on sustainable tailings management and industrial symbiosis. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. 12. Credit PED. View of tail race and dam showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Credit PED. View of tail race and dam showing dumping of construction rubble into river bed by rail car; and preparations for pouring a concrete cap onto tail race wall. Photo c. 1909. - Dam No. 4 Hydroelectric Plant, Potomac River, Martinsburg, Berkeley County, WV

  19. Microscopic understanding of heavy-tailed return distributions in an agent-based model

    NASA Astrophysics Data System (ADS)

    Schmitt, Thilo A.; Schäfer, Rudi; Münnix, Michael C.; Guhr, Thomas

    2012-11-01

    The distribution of returns in financial time series exhibits heavy tails. It has been found that gaps between the orders in the order book lead to large price shifts and thereby to these heavy tails. We set up an agent-based model to study this issue and, in particular, how the gaps in the order book emerge. The trading mechanism in our model is based on a double-auction order book. In situations where the order book is densely occupied with limit orders we do not observe fat-tailed distributions. As soon as less liquidity is available, a gap structure forms which leads to return distributions with heavy tails. We show that return distributions with heavy tails are an order-book effect if the available liquidity is constrained. This is largely independent of specific trading strategies.

  20. Extreme values and fat tails of multifractal fluctuations

    NASA Astrophysics Data System (ADS)

    Muzy, J. F.; Bacry, E.; Kozhemyak, A.

    2006-06-01

    In this paper we discuss the problem of the estimation of extreme event occurrence probability for data drawn from some multifractal process. We also study the heavy (power-law) tail behavior of probability density function associated with such data. We show that because of strong correlations, the standard extreme value approach is not valid and classical tail exponent estimators should be interpreted cautiously. Extreme statistics associated with multifractal random processes turn out to be characterized by non-self-averaging properties. Our considerations rely upon some analogy between random multiplicative cascades and the physics of disordered systems and also on recent mathematical results about the so-called multifractal formalism. Applied to financial time series, our findings allow us to propose an unified framework that accounts for the observed multiscaling properties of return fluctuations, the volatility clustering phenomenon and the observed “inverse cubic law” of the return pdf tails.

  1. Random-Walk Type Model with Fat Tails for Financial Markets

    NASA Astrophysics Data System (ADS)

    Matuttis, Hans-Geors

    Starting from the random-walk model, practices of financial markets are included into the random-walk so that fat tail distributions like those in the high frequency data of the SP500 index are reproduced, though the individual mechanisms are modeled by normally distributed data. The incorporation of local correlation narrows the distribution for "frequent" events, whereas global correlations due to technical analysis leads to fat tails. Delay of market transactions in the trading process shifts the fat tail probabilities downwards. Such an inclusion of reactions to market fluctuations leads to mini-trends which are distributed with unit variance.

  2. A statistical analysis of substorm associated tail activity

    NASA Astrophysics Data System (ADS)

    Hsu, Tung-Shin; McPherron, Robert L.

    2012-11-01

    Substorm onset timing is a critical issue in magnetotail dynamics research. Solar wind energy is accumulated in the magnetosphere and the configuration of the magnetosphere evolves toward an unstable state during the growth phase. At some point, the expansion phase begins and the stored energy is released through a variety of processes that return the magnetosphere to a lower energy state. In recovery the various processes die away. Unfortunately, the ground and magnetospheric signatures of onset, i.e. energy release, can be seen both in the growth phase prior to onset and in the expansion phase after onset. Some investigators refer to each of these events as a substorm. Tail observations suggest that most substorms have one event that differentiates the behavior of the tail field and plasma. We refer to this time as the "main substorm onset". Each substorm associated phenomenon is timed independently and then compared with main substorm onsets. ISEE-2 tail observations are used to examine the tail lobe magnetic conditions associated with substorms because ISEE-2 orbit has a high inclination and frequently observes lobe field. Approximately 70 ˜ 75% of tail lobe Bt and Bz change are associated with the main substorm onset. If the satellite is more than 3 Re above (below) the neutral sheet, 86% (57%) of plasma pressure dropouts are associated with substorms. We interpret our results as evidence that the effect of the growth phase is to drive the magnetosphere towards instability. As it approaches global instability local regions become temporarily unstable but are rapidly quenched. Eventually one of these events develops into the global instability that releases most of the stored energy and returns the magnetosphere to a more stable configuration.

  3. Wake structures behind a swimming robotic lamprey with a passively flexible tail

    PubMed Central

    Leftwich, Megan C.; Tytell, Eric D.; Cohen, Avis H.; Smits, Alexander J.

    2012-01-01

    SUMMARY A robotic lamprey, based on the silver lamprey, Ichthyomyzon unicuspis, was used to investigate the influence of passive tail flexibility on the wake structure and thrust production during anguilliform swimming. A programmable microcomputer actuated 11 servomotors that produce a traveling wave along the length of the lamprey body. The waveform was based on kinematic studies of living lamprey, and the shape of the tail was taken from a computer tomography scan of the silver lamprey. The tail was constructed of flexible PVC gel, and nylon inserts were used to change its degree of flexibility. Particle image velocimetry measurements using three different levels of passive flexibility show that the large-scale structure of the wake is dominated by the formation of two pairs of vortices per shedding cycle, as seen in the case of a tail that flexed actively according to a pre-defined kinematic pattern, and did not bend in response to fluid forces. When the tail is passively flexible, however, the large structures are composed of a number of smaller vortices, and the wake loses coherence as the degree of flexibility increases. Momentum balance calculations indicate that, at a given tailbeat frequency, increasing the tail flexibility yields less net force, but changing the cycle frequency to match the resonant frequency of the tail increases the force production. PMID:22246250

  4. Black-tailed prairie dog status and future conservation planning

    Treesearch

    Daniel W. Mulhern; Craig J. Knowles

    1997-01-01

    The black-tailed prairie dog is one of five prairie dog species estimated to have once occupied up to 100 million ha or more in North America. The area occupied by black-tailed prairie dogs has declined to approximately 2% of its former range. Conversion of habitat to other land uses and widespread prairie dog eradication efforts combined with sylvatic plague,

  5. A 70 Kiloparsec X-Ray Tail in the Cluster A3627

    NASA Technical Reports Server (NTRS)

    Sun, M.; Jones, C.; Forman, W.; Nulsen, P. E. J.; Donahue, M.; Voit, G. M.

    2006-01-01

    We present the discovery of a 70 kpc X-ray tail behind the small late-type galaxy ESO 137-001, in the nearby, hot (T=6.5 keV) merging cluster A3627, from both Chandra and XMM-Newton observations. The tail has a length-to-width ratio of approx. 10. It is luminous (L(0.5-2keV) approx 1041 ergs/s), with a temperature of approx. 0.7 keV and an X-ray gas mass of approx 10(exp 9) solar masses (approx 10% of the galaxy's stellar mass). We interpret this tail as the stripped interstellar medium of ESO 137-001 mixed with the hot cluster medium, with this blue galaxy being converted into a gas-poor galaxy. Three X-ray point sources are detected in the axis of the tail, which may imply active star formation there. The straightness and narrowness of the tail also imply that the turbulence in the intracluster medium is not strong on scales of 20-70 kpc.

  6. The Anatomy of the Long Tail of Consumer Demand

    NASA Astrophysics Data System (ADS)

    Broder, Andrei

    The long tail of consumer demand is consistent with two fundamentally different theories. The first, and more popular hypothesis, is that a majority of consumers have similar tastes and only few have any interest in niche content; the second, is that everyone is a bit eccentric, consuming both popular and niche products. By examining extensive data on user preferences for movies, music, web search, and web browsing, we found overwhelming support for the latter theory. Our investigation suggests an additional factor in the success of "infinite-inventory" retailers such as Netflix and Amazon: besides the significant revenue obtained from tail sales, tail availability may boost head sales by offering consumers the convenience of "one-stop shopping" for both their mainstream and niche interests.

  7. Measurements of atmospheric turbulence effects on tail rotor acoustics

    NASA Technical Reports Server (NTRS)

    Hagen, Martin J.; Yamauchi, Gloria K.; Signor, David B.; Mosher, Marianne

    1994-01-01

    Results from an outdoor hover test of a full-scale Lynx tail rotor are presented. The investigation was designed to further the understanding of the acoustics of an isolated tail rotor hovering out-of-ground effect in atmospheric turbulence, without the effects of the main rotor wake or other helicopter components. Measurements include simultaneous rotor performance, noise, inflow, and far-field atmospheric turbulence. Results with grid-generated inflow turbulence are also presented. The effects of atmospheric turbulence ingestion on rotor noise are quantified. In contradiction to current theories, increasing rotor inflow and rotor thrust were found to increase turbulence ingestion noise. This is the final report of Task 13A--Helicopter Tail Rotor Noise, of the NASA/United Kingdom Defense Research Agency cooperative Aeronautics Research Program.

  8. Tail autotomy affects bipedalism but not sprint performance in a cursorial Mediterranean lizard

    NASA Astrophysics Data System (ADS)

    Savvides, Pantelis; Stavrou, Maria; Pafilis, Panayiotis; Sfenthourakis, Spyros

    2017-02-01

    Running is essential in all terrestrial animals mainly for finding food and mates and escaping from predators. Lizards employ running in all their everyday functions, among which defense stands out. Besides flight, tail autotomy is another very common antipredatory strategy within most lizard families. The impact of tail loss to sprint performance seems to be species dependent. In some lizard species, tail shedding reduces sprint speed, in other species, increases it, and, in a few species, speed is not affected at all. Here, we aimed to clarify the effect of tail autotomy on the sprint performance of a cursorial lizard with particular adaptations for running, such as bipedalism and spike-like protruding scales (fringes) on the toepads that allow high speed on sandy substrates. We hypothesized that individuals that performed bipedalism, and have more and larger fringes, would achieve higher sprint performance. We also anticipated that tail shedding would affect sprint speed (though we were not able to define in what way because of the unpredictable effects that tail loss has on different species). According to our results, individuals that ran bipedally were faster; limb length and fringe size had limited effects on sprint performance whereas tail autotomy affected quadrupedal running only in females. Nonetheless, tail loss significantly affected bipedalism: the ability for running on hindlimbs was completely lost in all adult individuals and in 72.3% of juveniles.

  9. Tail autotomy affects bipedalism but not sprint performance in a cursorial Mediterranean lizard.

    PubMed

    Savvides, Pantelis; Stavrou, Maria; Pafilis, Panayiotis; Sfenthourakis, Spyros

    2017-02-01

    Running is essential in all terrestrial animals mainly for finding food and mates and escaping from predators. Lizards employ running in all their everyday functions, among which defense stands out. Besides flight, tail autotomy is another very common antipredatory strategy within most lizard families. The impact of tail loss to sprint performance seems to be species dependent. In some lizard species, tail shedding reduces sprint speed, in other species, increases it, and, in a few species, speed is not affected at all. Here, we aimed to clarify the effect of tail autotomy on the sprint performance of a cursorial lizard with particular adaptations for running, such as bipedalism and spike-like protruding scales (fringes) on the toepads that allow high speed on sandy substrates. We hypothesized that individuals that performed bipedalism, and have more and larger fringes, would achieve higher sprint performance. We also anticipated that tail shedding would affect sprint speed (though we were not able to define in what way because of the unpredictable effects that tail loss has on different species). According to our results, individuals that ran bipedally were faster; limb length and fringe size had limited effects on sprint performance whereas tail autotomy affected quadrupedal running only in females. Nonetheless, tail loss significantly affected bipedalism: the ability for running on hindlimbs was completely lost in all adult individuals and in 72.3% of juveniles.

  10. Thermo-mechanical properties and microfabric of fly ash-stabilized gold tailings.

    PubMed

    Lee, Joon Kyu; Shang, Julie Q; Jeong, Sangseom

    2014-07-15

    This paper studies the changes in thermal conductivity, temperature, and unconfined compressive strength of gold tailings and fly ash mixtures during the curing period of 5 days. The microfabric of the cured mixtures was investigated with mercury intrusion porosimetry (MIP). The mixture samples were prepared at their maximum dry unit weight and optimum moisture content. Effect of adding fly ash to gold tailings (i.e., 0, 20, and 40% of the dry weight of tailings) was examined, and a comparison was made on samples prepared at the same fly ash content by replacing gold tailings with humic acid (i.e., gold tailings and humic acid ratios of 100:0, 90:10, and 80:20 by weight) or by varying pore fluid chemistry (i.e., water and salt solutions of 1M NaCl and CaCl2). The results show that the initial thermal conductivity of the samples is sensitive to the mixture proportion and a declination in the thermal conductivity is observed due to hydration of fly ash and evaporation. Inclusion of fly ash and salts into gold tailings improves the unconfined compressive strength but the presence of humic acid in samples leads to the decrease of the strength. MIP results reveal the pore structure changes associated with the packing states of the samples that reflect the influential factors considered. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. Role of the tail in the regulated state of myosin 2

    PubMed Central

    Jung, HyunSuk; Billington, Neil; Thirumurugan, Kavitha; Salzameda, Bridget; Cremo, Christine R.; Chalovich, Joseph M.; Chantler, Peter D.; Knight, Peter J.

    2013-01-01

    Myosin 2 from vertebrate smooth muscle or non-muscle sources is in equilibrium between compact, inactive monomers and thick filaments under physiological conditions. In the inactive monomer, the two heads pack compactly together and the long tail is folded into three closely-packed segments that are associated chiefly with one of the heads. The molecular basis of the folding of the tail remains unexplained. Using electron microscopy, we show that compact monomers of smooth muscle myosin 2 have the same structure in both the native state and following specific, intramolecular photo-cross-linking between Cys109 of the regulatory light chain (RLC) and segment 3 of the tail. Non-specific cross-linking between lysine residues of the folded monomer by glutaraldehyde also does not perturb the compact conformation, and stabilises it against unfolding at high ionic strength. Sequence comparisons across phyla and myosin 2 isoforms suggest that folding of the tail is stabilised by ionic interactions between the positively-charged N-terminal sequence of the RLC and a negatively-charged region near the start of tail segment 3, and that phosphorylation of the RLC could perturb these interactions. Our results support the view that interactions between the heads and the distal tail perform a critical role in regulating activity of myosin 2 molecules through stabilising the compact monomer conformation. PMID:21419133

  12. NONINVASIVE, CONTINUOUS MEASUREMENT OF RAT TAIL SKIN TEMPERATURE BY RADIOTELEMETRY.

    EPA Science Inventory

    Tail skin temperature (Tsk) can provide a wealth of information on the thermoregulatory status of the rat. Drug- and toxic-induced changes in body temperature are often mediated by vasodilation or constriction of blood flow to the tail and Tsk can generally be used as an indica...

  13. Chimeric rabies glycoprotein with a transmembrane domain and cytoplasmic tail from Newcastle disease virus fusion protein incorporates into the Newcastle disease virion at reduced levels.

    PubMed

    Yu, Gui Mei; Zu, Shu Long; Zhou, Wei Wei; Wang, Xi Jun; Shuai, Lei; Wang, Xue Lian; Ge, Jin Ying; Bu, Zhi Gao

    2017-08-31

    Rabies remains an important worldwide health problem. Newcastle disease virus (NDV) was developed as a vaccine vector in animals by using a reverse genetics approach. Previously, our group generated a recombinant NDV (LaSota strain) expressing the complete rabies virus G protein (RVG), named rL-RVG. In this study, we constructed the variant rL-RVGTM, which expresses a chimeric rabies virus G protein (RVGTM) containing the ectodomain of RVG and the transmembrane domain (TM) and a cytoplasmic tail (CT) from the NDV fusion glycoprotein to study the function of RVG's TM and CT. The RVGTM did not detectably incorporate into NDV virions, though it was abundantly expressed at the surface of infected BHK-21 cells. Both rL-RVG and rL-RVGTM induced similar levels of NDV virus-neutralizing antibody (VNA) after initial and secondary vaccination in mice, whereas rabies VNA induction by rL-RVGTM was markedly lower than that induced by rL-RVG. Though rL-RVG could spread from cell to cell like that in rabies virus, rL-RVGTM lost this ability and spread in a manner similar to the parental NDV. Our data suggest that the TM and CT of RVG are essential for its incorporation into NDV virions and for spreading of the recombinant virus from the initially infected cells to surrounding cells.

  14. Flea abundance on black-tailed prairie dogs (Cynomys ludovicianus) increases during plague epizootics.

    PubMed

    Tripp, Daniel W; Gage, Kenneth L; Montenieri, John A; Antolin, Michael F

    2009-06-01

    Black-tailed prairie dogs (Cynomys ludovicianus) on the Great Plains of the United States are highly susceptible to plague, caused by the bacterium Yersinia pestis, with mortality on towns during plague epizootics often approaching 100%. The ability of flea-borne transmission to sustain disease spread has been questioned because of inefficiency of flea vectors. However, even with low individual efficiency, overall transmission can be increased if flea abundance (the number of fleas on hosts) increases. Changes in flea abundance on hosts during plague outbreaks were recorded during a large-scale study of plague outbreaks in prairie dogs in north central Colorado during 3 years (2004-2007). Fleas were collected from live-trapped black-tailed prairie dogs before and during plague epizootics and tested by PCR for the presence of Y. pestis. The predominant fleas were two prairie dog specialists (Oropsylla hirsuta and Oropsylla tuberculata cynomuris), and a generalist flea species (Pulex simulans) was also recorded from numerous mammals in the area. The three species differ in seasonal abundance, with greatest abundance in spring (February and March) and fall (September and October). Flea abundance and infestation intensity increased during epizootics and were highest on prairie dogs with Y. pestis-infected fleas. Seasonal occurrence of epizootics among black-tailed prairie dogs was found to coincide with seasonal peaks in flea abundance. Concentration of infected fleas on surviving animals may account for rapid spread of plague during epizootics. In particular, the role of the generalist flea P. simulans was previously underappreciated.

  15. Tails and bridges in the parabolic restricted three-body problem

    NASA Astrophysics Data System (ADS)

    Barrabés, Esther; Cors, Josep M.; Garcia-Taberner, Laura; Ollé, Mercè

    2017-12-01

    After a close encounter of two galaxies, bridges and tails can be seen between or around them. A bridge would be a spiral arm between a galaxy and its companion, whereas a tail would correspond to a long and curving set of debris escaping from the galaxy. The goal of this paper is to present a mechanism, applying techniques of dynamical systems theory, that explains the formation of tails and bridges between galaxies in a simple model, the so-called parabolic restricted three-body problem, i.e. we study the motion of a particle under the gravitational influence of two primaries describing parabolic orbits. The equilibrium points and the final evolutions in this problem are recalled,and we show that the invariant manifolds of the collinear equilibrium points and the ones of the collision manifold explain the formation of bridges and tails. Massive numerical simulations are carried out and their application to recover previous results are also analysed.

  16. Anti-Inflammatory Properties of Brazilian Green Propolis Encapsulated in a γ-Cyclodextrin Complex in Mice Fed a Western-Type Diet.

    PubMed

    Rimbach, Gerald; Fischer, Alexandra; Schloesser, Anke; Jerz, Gerold; Ikuta, Naoko; Ishida, Yoshiyuki; Matsuzawa, Ryota; Matsugo, Seiichi; Huebbe, Patricia; Terao, Keiji

    2017-05-26

    Ageing is often accompanied by chronic inflammation. A fat- and sugar-rich Western-type diet (WTD) may accelerate the ageing phenotype. Cell culture studies have indicated that artepillin C-containing Brazilian green propolis exhibits anti-inflammatory properties. However, little is known regarding its anti-inflammatory potential in mouse liver in vivo. In this study, female C57BL/6NRj wild-type mice were fed a WTD, a WTD supplemented with Brazilian green propolis supercritical extract (GPSE) encapsulated in γ-cyclodextrin (γCD) or a WTD plus γCD for 10 weeks. GPSE-γCD did not affect the food intake, body weight or body composition of the mice. However, mRNA levels of the tumour necrosis factor α were significantly downregulated ( p < 0.05) in these mice compared to those in the WTD-fed controls. Furthermore, the gene expression levels of other pro-inflammatory markers, including serum amyloid P, were significantly ( p < 0.001) decreased following GPSE-γCD treatment. GPSE-γCD significantly induced hepatic ferritin gene expression ( p < 0.01), which may contribute to its anti-inflammatory properties. Conversely, GPSE-γCD did not affect the biomarkers of endogenous antioxidant defence, including catalase, glutathione peroxidase-4, paraoxonase-1, glutamate cysteine ligase and nuclear factor erythroid 2-related factor-2 (Nrf2). Overall, the present data suggest that dietary GPSE-γCD exhibits anti-inflammatory, but not antioxidant activity in mouse liver in vivo. Thus, GPSE-γCD has the potential to serve as a natural hepatoprotective bioactive compound for dietary-mediated strategies against chronic inflammation.

  17. Modeled Impacts of Chronic Wasting Disease on White-Tailed Deer in a Semi-Arid Environment.

    PubMed

    Foley, Aaron M; Hewitt, David G; DeYoung, Charles A; DeYoung, Randy W; Schnupp, Matthew J

    2016-01-01

    White-tailed deer are a culturally and economically important game species in North America, especially in South Texas. The recent discovery of chronic wasting disease (CWD) in captive deer facilities in Texas has increased concern about the potential emergence of CWD in free-ranging deer. The concern is exacerbated because much of the South Texas region is a semi-arid environment with variable rainfall, where precipitation is strongly correlated with fawn recruitment. Further, the marginally productive rangelands, in combination with erratic fawn recruitment, results in populations that are frequently density-independent, and thus sensitive to additive mortality. It is unknown how a deer population in semi-arid regions would respond to the presence of CWD. We used long-term empirical datasets from a lightly harvested (2% annual harvest) population in conjunction with 3 prevalence growth rates from CWD afflicted areas (0.26%, 0.83%, and 2.3% increases per year) via a multi-stage partially deterministic model to simulate a deer population for 25 years under four scenarios: 1) without CWD and without harvest, 2) with CWD and without harvest, 3) with CWD and male harvest only, and 4) with CWD and harvest of both sexes. The modeled populations without CWD and without harvest averaged a 1.43% annual increase over 25 years; incorporation of 2% annual harvest of both sexes resulted in a stable population. The model with slowest CWD prevalence rate growth (0.26% annually) without harvest resulted in stable populations but the addition of 1% harvest resulted in population declines. Further, the male age structure in CWD models became skewed to younger age classes. We incorporated fawn:doe ratios from three CWD afflicted areas in Wisconsin and Wyoming into the model with 0.26% annual increase in prevalence and populations did not begin to decline until ~10%, ~16%, and ~26% of deer were harvested annually. Deer populations in variable environments rely on high adult

  18. Modeled Impacts of Chronic Wasting Disease on White-Tailed Deer in a Semi-Arid Environment

    PubMed Central

    Hewitt, David G.; DeYoung, Charles A.; DeYoung, Randy W.; Schnupp, Matthew J.

    2016-01-01

    White-tailed deer are a culturally and economically important game species in North America, especially in South Texas. The recent discovery of chronic wasting disease (CWD) in captive deer facilities in Texas has increased concern about the potential emergence of CWD in free-ranging deer. The concern is exacerbated because much of the South Texas region is a semi-arid environment with variable rainfall, where precipitation is strongly correlated with fawn recruitment. Further, the marginally productive rangelands, in combination with erratic fawn recruitment, results in populations that are frequently density-independent, and thus sensitive to additive mortality. It is unknown how a deer population in semi-arid regions would respond to the presence of CWD. We used long-term empirical datasets from a lightly harvested (2% annual harvest) population in conjunction with 3 prevalence growth rates from CWD afflicted areas (0.26%, 0.83%, and 2.3% increases per year) via a multi-stage partially deterministic model to simulate a deer population for 25 years under four scenarios: 1) without CWD and without harvest, 2) with CWD and without harvest, 3) with CWD and male harvest only, and 4) with CWD and harvest of both sexes. The modeled populations without CWD and without harvest averaged a 1.43% annual increase over 25 years; incorporation of 2% annual harvest of both sexes resulted in a stable population. The model with slowest CWD prevalence rate growth (0.26% annually) without harvest resulted in stable populations but the addition of 1% harvest resulted in population declines. Further, the male age structure in CWD models became skewed to younger age classes. We incorporated fawn:doe ratios from three CWD afflicted areas in Wisconsin and Wyoming into the model with 0.26% annual increase in prevalence and populations did not begin to decline until ~10%, ~16%, and ~26% of deer were harvested annually. Deer populations in variable environments rely on high adult

  19. Plant growth-promoting bacteria for phytostabilization of mine tailings.

    PubMed

    Grandlic, Christopher J; Mendez, Monica O; Chorover, Jon; Machado, Blenda; Maier, Raina M

    2008-03-15

    Eolian dispersion of mine tailings in arid and semiarid environments is an emerging global issue for which economical remediation alternatives are needed. Phytostabilization, the revegetation of these sites with native plants, is one such alternative. Revegetation often requires the addition of bulky amendments such as compost which greatly increases cost. We report the use of plant growth-promoting bacteria (PGPB) to enhance the revegetation of mine tailings and minimize the need for compost amendment. Twenty promising PGPB isolates were used as seed inoculants in a series of greenhouse studies to examine revegetation of an extremely acidic, high metal contenttailings sample previously shown to require 15% compost amendment for normal plant growth. Several isolates significantly enhanced growth of two native species, quailbush and buffalo grass, in tailings. In this study, PGPB/compost outcomes were plant specific; for quailbush, PGPB were most effective in combination with 10% compost addition while for buffalo grass, PGPB enhanced growth in the complete absence of compost. Results indicate that selected PGPB can improve plant establishment and reduce the need for compost amendment. Further, PGPB activities necessary for aiding plant growth in mine tailings likely include tolerance to acidic pH and metals.

  20. Crucial advantages of tail use in the evolution of vertebrate terrestrial locomotion

    NASA Astrophysics Data System (ADS)

    Astley, Henry; McInroe, Benjamin; Kawano, Sandy; Blob, Rick; Goldman, Daniel

    In the invasion of terrestrial environment, the first tetrapods faced the challenge of locomotion on flowable substrates (e.g. sand and mud), sometimes oriented at inclines. Although the morphology of many early tetrapods is known, robotic studies have revealed that effective locomotion on these substrates also depends strongly upon kinematics; slight differences in movements of the same appendage can lead to success or failure. Using a model organism (the mudskipper) and a robotic physical model, we demonstrate how muscular tails provided critical locomotor advantages on granular substrates that the first invaders of land likely encountered. Mudskippers use their tails for additional propulsion with increasing frequency as the slope of the granular material increases, and the decline in locomotor performance with slope is shallower when the tail is used. Experiments with a robotic model of the mudskipper showed that, while the tail did not always provide a benefit to locomotion, use of the tail made the robot's performance more robust, achieving effective locomotion on a wider range of slopes, limb postures and foot placements. These results suggest that, rather than simply being an inert appendage, the tails of early tetrapods were vital to their first forays into terrestrial habitats.

  1. Biological effects of long term fine limestone tailings discharge in a fjord ecosystem.

    PubMed

    Brooks, Lucy; Melsom, Fredrik; Glette, Tormod

    2015-07-15

    Benthic infaunal data collected from 1993 to 2010 were analysed to examine the effect of long term discharge of fine limestone tailings on macrofaunal species assemblages in a fjord. Relative distance from the outfall and proportion of fine tailings in the sediment were correlated with benthic community structure. Diversity decreased with increasing proportion of fine tailings. Biological Traits Analysis (BTA) was used to explore the temporal and spatial effects of the tailings gradient on macrofaunal functional attributes. BTA revealed that all stations along a pressure gradient of fine limestone tailings were dominated by free-living species. As the proportion of fine tailings in the sediment increased, there was an increase in fauna that were smaller, highly mobile, living on or nearer the surface sediment, with shorter lifespans. There was a decrease in permanent tube dwellers, those fauna with low or no mobility, that live deeper in the sediment and have longer lifespans (>5 yrs). Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. MESSENGER Observations of Extreme Loading and Unloading of Mercury's Magnetic Tail

    NASA Technical Reports Server (NTRS)

    Slavin, James A.; Anderson, Brian J.; Baker, Daniel N.; Benna, Mehdi; Boardsen, Scott A.; Gloeckler, George; Gold, Robert E.; Ho, George C.; Korth, Haje; Krimigis, Stamatios M.; hide

    2010-01-01

    During MESSENGER's third flyby of Mercury, the magnetic field in the planet's magnetotail increased by factors of 2 to 3.5 over intervals of 2 to 3 min. Magnetospheric substorms at Earth are powered by similar tail loading, but the amplitude is approx.10 times less and typical durations are approx.1 hour. The extreme tail loading observed at Mercury implies that the relative intensity of sub storms must be much larger than at Earth. The correspondence between the duration of tail field enhancements and the characteristic time for the Dungey cycle, which describes plasma circulation through Mercury's magnetosphere. suggests that such circulation determines substorm timescale. A key aspect of tail unloading during terrestrial substorms is the acceleration of energetic charged particles, but no acceleration signatures were seen during the MESSENGER flyby.

  3. Theoretical aerodynamic characteristics of a family of slender wing-tail-body combinations

    NASA Technical Reports Server (NTRS)

    Lomax, Harvard; Byrd, Paul F

    1951-01-01

    The aerodynamic characteristics of an airplane configuration composed of a swept-back, nearly constant chord wing and a triangular tail mounted on a cylindrical body are presented. The analysis is based on the assumption that the free-stream Mach number is near unity or that the configuration is slender. The calculations for the tail are made on the assumption that the vortex system trailing back from the wing is either a sheet lying entirely in the plane of the flat tail surface or has completely "rolled up" into two point vortices that lie either in, above, or below the plane of the tail surface.

  4. VIEW OF BOEING 737200 FUSELAGE FROM TOP LEVEL OF TAIL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF BOEING 737-200 FUSELAGE FROM TOP LEVEL OF TAIL DOCK AND. A NEW SAFETY CABLE FROM THE TAIL DOCK WILL ALLOW INSPECTORS TO WALK UP AND DOWN THE FUSELAGE TO CHECK FOR CRACKS OR MISSING FASTENERS. - Greater Buffalo International Airport, Maintenance Hangar, Buffalo, Erie County, NY

  5. Heavy metal leaching from mine tailings as affected by plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhu, D.; Schwab, A.P.; Banks, M.K.

    A column experiment was conducted to determine the impact of soil cover and plants on heavy metal leaching from mine tailings and heavy metal contaminated soil. Columns made of PVC were constructed with 30 cm subsoil covered by 30 cm of mine tailings followed by 0, 30, or 60 cm subsoil covered by 30 cm of mine tailings followed by 0, 30, or 60 cm of clean topsoil. Two grasses, tall fescue (Festuca arundinacea Schreb.) and big bluestem (Andropogon gerardii), were grown in the columns. The columns were leached at a slow rate for 1 yr with a 0.001 Mmore » CaCl{sub 2} solution under unsaturated conditions. The presence of both tall fescue and big bluestem increased Zn and Cd concentrations in the leachate. Lead concentrations in leachates were not affected by the presence of plants. Although plants generally reduced the total amount of water leached, total mass of Zn and Cd leached generally was not impacted by plants. Total mass of Pb leached was positively correlated with total leachate collected from each column. Covering the mine tailings with 60 cm of topsoil increased the mass of Zn and Cd leached relative to no topsoil. When the subsoil was absent, Zn and Cd leaching increased by as much as 20-fold, verifying the ability of soil to act as a sink for metals. Mine tailing remediation by establishing vegetation can reduce Pb movement but may enhance short-term Cd and Zn leaching. However, the changes were relatively small and do not outweigh the benefits of using vegetation in mine tailings reclamation.« less

  6. A Yurok Story: How the Animals Got Their Tails.

    ERIC Educational Resources Information Center

    Tripp, Maria

    This story was told to the author by her grandmother, a Yurok born at Pecwan in 1898. Long ago, at a council meeting, the animals decided to ask the Great Creator for tails. He agreed and promised to give each animal a tail the next morning. The first animal to get up would have first choice. Coyote built a big fire and tried hard to stay awake…

  7. Double streams of protons in the distant geomagnetic tail

    NASA Technical Reports Server (NTRS)

    Villante, U.; Lazarus, A. J.

    1975-01-01

    Two intermingled streams of protons have been observed in the distant geomagnetic tail. The number densities of the two streams are comparable, and their velocity difference tends to lie along the field direction. The lower-velocity stream is probably composed of magnetosheath protons which have diffused through the boundary of the distant tail. The higher-velocity stream appears to originate in the field reversal region.

  8. Correlation between length and tilt of lipid tails

    NASA Astrophysics Data System (ADS)

    Kopelevich, Dmitry I.; Nagle, John F.

    2015-10-01

    It is becoming recognized from simulations, and to a lesser extent from experiment, that the classical Helfrich-Canham membrane continuum mechanics model can be fruitfully enriched by the inclusion of molecular tilt, even in the fluid, chain disordered, biologically relevant phase of lipid bilayers. Enriched continuum theories then add a tilt modulus κθ to accompany the well recognized bending modulus κ. Different enrichment theories largely agree for many properties, but it has been noticed that there is considerable disagreement in one prediction; one theory postulates that the average length of the hydrocarbon chain tails increases strongly with increasing tilt and another predicts no increase. Our analysis of an all-atom simulation favors the latter theory, but it also shows that the overall tail length decreases slightly with increasing tilt. We show that this deviation from continuum theory can be reconciled by consideration of the average shape of the tails, which is a descriptor not obviously includable in continuum theory.

  9. Mineralogical and geochemical characterization of arsenic in an abandoned mine tailings of Korea.

    PubMed

    Ahn, Joo Sung; Park, Young Seog; Kim, Ju-Yong; Kim, Kyoung-Woong

    2005-04-01

    The mineralogical and chemical characteristics of As solid phases in arsenic-rich mine tailings from the Nakdong As-Bi mine in Korea was investigated. The tailings generated from the ore roasting process contained 4.36% of As whereas the concentration was up to 20.2% in some tailings from the cyanidation process for the Au extraction. Thin indurated layers and other secondary precipitates had formed at the surfaces of the tailings piles and the As contents of the hardened layers varied from 2.87 to 16.0%. Scorodite and iron arsenate (Fe3AsO7) were the primary As-bearing crystalline minerals. Others such as arsenolamprite, bernardite and titanium oxide arsenate were also found. The amorphous As-Fe phases often showed framboidal aggregates and gel type textures with desiccation cracks. Sequential extraction results also showed that 55.7-91.1% of the As in tailings were NH(4)-oxalate extractable As, further confirmed the predominance of amorphous As-Fe solid phases. When the tailings were equilibrated with de-ionized water, the solution exhibited extremely acidic conditions (pH 2.01-3.10) and high concentrations of dissolved As (up to 29.5 mg L(-1)), indicating high potentials for As to be released during rainfall events. The downstream water was affected by drainage from tailings and contained 12.7-522 microg L(-1) of As. The amorphous As-Fe phases in tailings have not entirely been stabilized through the long term natural weathering processes. To remediate the environmental harms they had caused, anthropogenic interventions to stabilize or immobilize As in the tailings pile should be explored.

  10. Automated registration of tail bleeding in rats.

    PubMed

    Johansen, Peter B; Henriksen, Lars; Andresen, Per R; Lauritzen, Brian; Jensen, Kåre L; Juhl, Trine N; Tranholm, Mikael

    2008-05-01

    An automated system for registration of tail bleeding in rats using a camera and a user-designed PC-based software program has been developed. The live and processed images are displayed on the screen and are exported together with a text file for later statistical processing of the data allowing calculation of e.g. number of bleeding episodes, bleeding times and bleeding areas. Proof-of-principle was achieved when the camera captured the blood stream after infusion of rat whole blood into saline. Suitability was assessed by recording of bleeding profiles in heparin-treated rats, demonstrating that the system was able to capture on/off bleedings and that the data transfer and analysis were conducted successfully. Then, bleeding profiles were visually recorded by two independent observers simultaneously with the automated recordings after tail transection in untreated rats. Linear relationships were found in the number of bleedings, demonstrating, however, a statistically significant difference in the recording of bleeding episodes between observers. Also, the bleeding time was longer for visual compared to automated recording. No correlation was found between blood loss and bleeding time in untreated rats, but in heparinized rats a correlation was suggested. Finally, the blood loss correlated with the automated recording of bleeding area. In conclusion, the automated system has proven suitable for replacing visual recordings of tail bleedings in rats. Inter-observer differences can be eliminated, monotonous repetitive work avoided, and a higher through-put of animals in less time achieved. The automated system will lead to an increased understanding of the nature of bleeding following tail transection in different rodent models.

  11. The tail sheath structure of bacteriophage T4: a molecular machine for infecting bacteria

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aksyuk, Anastasia A.; Leiman, Petr G.; Kurochkina, Lidia P.

    2009-07-22

    The contractile tail of bacteriophage T4 is a molecular machine that facilitates very high viral infection efficiency. Its major component is a tail sheath, which contracts during infection to less than half of its initial length. The sheath consists of 138 copies of the tail sheath protein, gene product (gp) 18, which surrounds the central non-contractile tail tube. The contraction of the sheath drives the tail tube through the outer membrane, creating a channel for the viral genome delivery. A crystal structure of about three quarters of gp18 has been determined and was fitted into cryo-electron microscopy reconstructions of themore » tail sheath before and after contraction. It was shown that during contraction, gp18 subunits slide over each other with no apparent change in their structure.« less

  12. RICO Graduate Student Research Flight: The Island Tail Objective

    NASA Astrophysics Data System (ADS)

    Small, J. D.; Anderson-Bereznicki, S. D.; Medeiros, B.; Nuijens, L.; Henry, C. K.; O'Donnell, D. M.; Morales, F.; Shen, H.

    2005-12-01

    The Rain in Cumulus over the Ocean (RICO) project was an intensive field project aimed to study and understand precipitation processes in trade wind cumulus. The project took place from Nov 23, 2004 until Jan 25, 2005 on two small islands of the Lesser Antilles, Antigua and Barbuda, where trade wind cumulus fields frequently occur during suppressed wintertime conditions. RICO provided a unique combination of research and education by offering the RICO Graduate Seminar Series and the development and implementation of a graduate student designed and directed research flight. One of the main goals of the graduate student research flight was to allow graduate students to participate in the process of developing a research flight plan and identifying scientific goals and objectives first-hand. Added benefits included the possibility of addressing scientific questions not included in the main RICO objectives. This also involved collaboration when discussing different ideas and initiatives and the full development of all stages of the research flight including the coordination of two research aircraft (NCAR-C130, University of Wyoming King Air), one research vessel (RV Seward Johnson), S-Pol radar site and real time operations center satellite information. Seventeen graduate students from both the US and Europe developed two different plans to be presented to RICO project principle investigators; both of which were approved. The island tail objective aimed at characterizing the line of clouds known as 'island tails' that frequently form off the leeward coast of the Caribbean islands. This objective was successful in its implementation on Jan 18, 2005 with measurements made in vigorous, waterspout producing tail clouds immediately downwind of Barbuda. The investigation of these 'tails' fills a void in current cloud physics research since it is the first time this ubiquitous feature of trade-wind islands has been the focus of careful study. Scientific questions to be

  13. The longest faun tail forming dreadlocks with underlying spina bifida occulta.

    PubMed

    Brar, Balvinder Kaur; Mahajan, Bharat Bhushan; Mittal, Jyotisterna

    2013-04-15

    Spina bifida is a developmental anomaly characterized by defective closure of the bony encasement of the spinal cord through which the spinal cord and meninges may or may not protrude. We report a rare case of a very long faun tail, which was in the form of a 20 inch long tail originating from the lumbosacral area in a rhomboidal pattern, measuring 10 x 8 inches. The case is being reported for its rare presentation of a 20 inch long faun tail with underlying spina bifida occulta.

  14. A prophage tail-like protein is deployed by Burkholderia bacteria to feed on fungi.

    PubMed

    Swain, Durga Madhab; Yadav, Sunil Kumar; Tyagi, Isha; Kumar, Rahul; Kumar, Rajeev; Ghosh, Srayan; Das, Joyati; Jha, Gopaljee

    2017-09-01

    Some bacteria can feed on fungi, a phenomenon known as mycophagy. Here we show that a prophage tail-like protein (Bg_9562) is essential for mycophagy in Burkholderia gladioli strain NGJ1. The purified protein causes hyphal disintegration and inhibits growth of several fungal species. Disruption of the Bg_9562 gene abolishes mycophagy. Bg_9562 is a potential effector secreted by a type III secretion system (T3SS) and is translocated into fungal mycelia during confrontation. Heterologous expression of Bg_9562 in another bacterial species, Ralstonia solanacearum, confers mycophagous ability in a T3SS-dependent manner. We propose that the ability to feed on fungi conferred by Bg_9562 may help the bacteria to survive in certain ecological niches. Furthermore, considering its broad-spectrum antifungal activity, the protein may be potentially useful in biotechnological applications to control fungal diseases.Some bacteria can feed on live fungi through unclear mechanisms. Here, the authors show that a T3SS-secreted protein, which is homologous to phage tail proteins, allows a Burkholderia gladioli strain to kill and feed on various fungal species.

  15. Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo.

    PubMed

    Wu, Lin; Pan, Lifeng; Wei, Zhiyi; Zhang, Mingjie

    2011-02-11

    The unconventional myosin VIIa (MYO7A) is one of the five proteins that form a network of complexes involved in formation of stereocilia. Defects in these proteins cause syndromic deaf-blindness in humans [Usher syndrome I (USH1)]. Many disease-causing mutations occur in myosin tail homology 4-protein 4.1, ezrin, radixin, moesin (MyTH4-FERM) domains in the myosin tail that binds to another USH1 protein, Sans. We report the crystal structure of MYO7A MyTH4-FERM domains in complex with the central domain (CEN) of Sans at 2.8 angstrom resolution. The MyTH4 and FERM domains form an integral structural and functional supramodule binding to two highly conserved segments (CEN1 and 2) of Sans. The MyTH4-FERM/CEN complex structure provides mechanistic explanations for known deafness-causing mutations in MYO7A MyTH4-FERM. The structure will also facilitate mechanistic and functional studies of MyTH4-FERM domains in other myosins.

  16. The formation and potential importance of cemented layers in inactive sulfide mine tailings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blowes, D.W.; Reardon, E.J.; Cherry, J.A.

    Investigations of inactive sulfide-rich tailings impoundments at the Heath Steele (New Brunswick) and Waite Amulet (Quebec) minesites have revealed two distinct types of cemented layers or hardpans. That at Heath Steele is 10-15 cm thick, occurs 20-30 cm below the depth of active oxidation, is continuous throughout the tailings impoundment, and is characterized by cementation of tailings by gypsum and Fe(II) solid phases, principally melanterite. Hardpan at the Waite Amulet site is only 1-5 cm thick, is laterally discontinuous (10-100 cm), occurs at the depth of active oxidation, and is characterized by cementation of tailings by Fe(III) minerals, principally goethite,more » lepidocrocite, ferrihydrite, and jarosite. At Heath Steele, an accumulation of gas-phase CO{sub 2}, of up to 60{percent} of the pore gas, occurs below the hardpan. The calculated diffusivity of the hardpan layer is only about 1/100 that of the overlying, uncemented tailings. The pore-water chemistry at Heath Steele has changed little over a 10-year period, suggesting that the cemented layer restricts the movement of dissolved metals through the tailings and also acts as a zone of metal accumulation. Generation of a cemented layer therefore has significant environmental and economic implications. It is likely that, in sulfide-rich tailings impoundments, the addition of carbonate-rich buffering material during the late stages of tailings deposition would enhance the formation of hardpan layers.« less

  17. On the large-scale structure of the tail current as measured by THEMIS

    NASA Astrophysics Data System (ADS)

    Kalegaev, V. V.; Alexeev, I. I.; Nazarkov, I. S.; Angelopoulos, V.; Runov, A.

    2014-11-01

    The magnetic field structure and the spatial characteristics of the large-scale currents in the magnetospheric tail were studied during quiet and moderately disturbed geomagnetic conditions in 2009. The magnetic field of the currents other than the tail current was calculated in terms of a paraboloid model of the Earth’s magnetosphere, A2000, and was subtracted from measurements. It was found on the base of obtained tail current magnetic field radial distribution that the inner edge of the tail current sheet is located in the night side magnetosphere, at distances of about 10 RE and of about 7 RE during quiet and disturbed periods respectively. During the disturbance of February 14, 2009 (Dstmin ∼ -35 nT), the Bx and the Bz component of the tail current magnetic field near its inner edge were about 60 nT, and -60 nT that means that strong cross-tail current have been developed. The tail current parameters at different time moments during February 14, 2009 have been estimated. Solar wind conditions during this event were consistent with those during moderate magnetic storms with minimum Dst of about -100 nT. However, the magnetospheric current systems (magnetopause and cross-tail currents) were located at larger geocentric distances than typical during the 2009 extremely quiet epoch and did not provide the expected Dst magnitude. Very small disturbance on the Earth’s surface was detected consistent with an “inflated” magnetosphere.

  18. Study on immobilization and migration of nuclide u in superficial soil of uranium tailings pond

    NASA Astrophysics Data System (ADS)

    Chang, Zhe; Zhou, Shukui

    2017-05-01

    The uranium tailings in southern China was used as the object of study to study the fixation and migration characteristics of nuclide U in shallow tailings. The results showed that the precipitation of tailings in the tailings soil was not linearly related to the depth during the acid rain leaching process. Tailings soil in the role of fixatives, when the lime as a fixative, the tailings of different soil uranium in 20 days after the re-precipitation. However, when lime and ammonium phosphate were used as fixing agents, the cumulative precipitation of U had a significant effect, and the migration of uranium was inhibited.

  19. Using white-tailed deer (Odocoileus virginianus) in infectious disease research

    USDA-ARS?s Scientific Manuscript database

    Between 1940 and 2004 over 335 emerging infectious disease events were reported. The majority involved zoonoses, most of which were of wildlife origin or had an important wildlife host. There is reason to believe this trend of increasing emerging diseases will continue. For that reason, understandin...

  20. Recovery of valuable metals from polymetallic mine tailings by natural microbial consortium.

    PubMed

    Vardanyan, Narine; Sevoyan, Garegin; Navasardyan, Taron; Vardanyan, Arevik

    2018-05-28

    Possibilities for the recovery of non-ferrous and precious metals from Kapan polymetallic mine tailings (Armenia) were studied. The aim of this paper was to study the possibilities of bioleaching of samples of concentrated tailings by the natural microbial consortium of drainage water. The extent of extraction of metals from the samples of concentrated tailings by natural microbial consortium reached 41-55% and 53-73% for copper and zinc, respectively. Metal leaching efficiencies of pure culture Leptospirillum ferrooxidans Teg were higher, namely 47-93% and 73-81% for copper and zinc, respectively. The content of gold in solid phase of tailings increased about 7-16% and 2-9% after bio-oxidation process by L. ferrooxidans Teg and natural microbial consortium, respectively. It was shown that bioleaching of the samples of tailings could be performed using the natural consortium of drainage water. However, to increase the intensity of the recovery of valuable metals, natural consortium of drainage water combined with iron-oxidizing L. ferrooxidans Teg has been proposed.

  1. Acute and repeated activation of male sexual behavior by tail pinch: opioid and dopaminergic mechanisms.

    PubMed

    Leyton, M; Stewart, J

    1996-07-01

    We studied the effect of tail pinch on male sexual behavior and its neurochemical basis. Male rats were gonadectomized and maintained on low doses of testosterone propionate (20.0 micrograms/day). Tail pinch significantly increased the percentage of males that mounted, intromitted, and ejaculated within a 30-min test, and these increases were attenuated by both pimozide (1.0 mg/kg, i.p.) and by naloxone (0.5, 1.0, and 2.0 mg/kg, s.c.). Moreover, tail pinch in the presence of an estrous female led to significantly increased female-directed behavior 48 h later during a test without tail pinch. Repeated tail pinch tests led to progressively more sexual activity, and the development of this behavioral sensitization was prevented by naloxone. These findings suggest that tail pinch increases the salience of the incentive characteristics of the female. Furthermore, during subsequent tests, with or without tail pinch, the increased salience of the female remains, as measured by the continued increases in sexual activity. These acute and sensitized behavioral increases might result from tail pinch-induced activation of the midbrain dopamine system via an opioid mechanism; either preventing tail pinch-induced dopamine activation (by an opioid antagonist) or blocking the effects of dopamine activation (by a dopamine antagonist) attenuated the long-term facilitation of sexual behavior seen after pairing the female with tail pinch.

  2. Flapping foil power generator performance enhanced with a spring-connected tail

    NASA Astrophysics Data System (ADS)

    Liu, Zhengliang; Tian, Fang-Bao; Young, John; Lai, Joseph C. S.

    2017-12-01

    The flexibility effects on the performance of a flapping foil power generator are numerically studied by using the immersed boundary-lattice Boltzmann method at a Reynolds number of 1100. The flapping foil system consists of a rigid NACA0015 foil undergoing harmonic pitch and plunge motions and a passively actuated flat plate pinned to the trailing edge of the rigid foil. The flexibility is modeled by a torsional spring model at the conjuncture of the rigid foil and the tail. Here, a parametric study on mass density and natural frequency is conducted under the optimum kinematic condition of the rigid system identified from the literature and numerical simulations made for reduced frequency f* = 0.04-0.24 and pitch amplitude θ0 = 40°-90°. Four typical cases are discussed in detail by considering time histories of hydrodynamic loads and tail deformations under the optimal and non-optimal kinematic conditions. Results show that under the rigid-system optimal kinematic condition, a tail with appropriate mass density (μ = 0.60) and resonant frequency ( fr*=1.18 ) can improve the maximum efficiency by 7.24% accompanied by an increase of 6.63% in power compared to those of a rigid foil with a rigid tail. This is because the deflection of the tail reduces the low pressure region on the pressure surface (i.e., the lower surface during the upstroke or the upper surface during the downstroke) caused by the leading edge vortex after the stroke reversal, resulting in a higher efficiency. At high flapping frequencies, a spring-connected tail ( fr*=0.13 ) eliminates the large spike in the moment observed in high stiffness cases, reducing the power required for the pitch motion, resulting in 117% improvement in efficiency over that with a rigid tail at a reduced frequency of 0.24.

  3. Gecko CD59 Is Implicated in Proximodistal Identity during Tail Regeneration

    PubMed Central

    Jiang, Shengjuan; Zhou, Weijuan; Liu, Yan; Wang, Yingjie; Gu, Qing; Gu, Yun; Dong, Yingying; Liu, Mei; Gu, Xingxing; Ding, Fei; Gu, Xiaosong

    2011-01-01

    Several adult reptiles, such as Gekko japonicus, have the ability to precisely re-create a missing tail after amputation. To ascertain the associated acquisition of positional information from blastemal cells and the underlying molecular mechanism of tail regeneration, a candidate molecule CD59 was isolated from gecko. CD59 transcripts displayed a graded expression in the adult gecko spinal cord with the highest level in the anterior segment, with a stable expression along the normal tail. After tail amputation, CD59 transcripts in the spinal cord proximal to the injury sites increased markedly at 1 day and 2 weeks; whereas in the regenerating blastema, strong CD59 positive signals were detected in the blastemal cells anterior to the blastema, with a gradual decrease along the proximodistal (PD) axis. When treated with RA following amputation, CD59 transcripts in the blastema were up-regulated. PD confrontation assays revealed that the proximal blastema engulfed the distal one after in vitro culture, and rabbit-anti human CD59 antibody was able to block this PD engulfment. Overexpression of the CD59 during tail regeneration causes distal blastemal cells to translocate to a more proximal location. Our results suggest that position identity is not restricted to amphibian limb regeneration, but has already been established in tail blastema of reptiles. The CD59, a cell surface molecule, acted as a determinant of proximal–distal cell identity. PMID:21464923

  4. 10 CFR 40.2a - Coverage of inactive tailings sites.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Coverage of inactive tailings sites. 40.2a Section 40.2a Energy NUCLEAR REGULATORY COMMISSION DOMESTIC LICENSING OF SOURCE MATERIAL General Provisions § 40.2a Coverage of inactive tailings sites. (a) Prior to the completion of the remedial action, the Commission...

  5. Population characteristics of a central Appalachian white tailed deer herd

    Treesearch

    Tyler A. Campbell; Benjamin R. Laseter; W. Mark Ford; Karl V. Miller; Karl V. Miller

    2005-01-01

    Reliable estimates of white-tailed deer (Odocoileus virginianus) population parameters are needed for effective population management. We used radiotelemetrv to compare survival and cause-specific mortality rates between male and female white-tailed deer and present reproductive data for a high-density deer herd in the central Appalachians of West Virginia during...

  6. Comparison of neural histomorphology in tail tips from pigs docked using clippers or cautery iron.

    PubMed

    Kells, N J; Beausoleil, N J; Johnson, C B; Sutherland, M A; Morrison, R S; Roe, W

    2017-07-01

    Tail docking of pigs is commonly performed to reduce the incidence of unwanted tail-biting behaviour. Two docking methods are commonly used: blunt trauma cutting (i.e. using side clippers), or cutting and concurrent cauterisation using a hot cautery iron. A potential consequence of tail amputation is the development of neuromas at the docking site. Neuromas have been linked to neuropathic pain, which can influence the longer-term welfare of affected individuals. To determine whether method of tail docking influences the extent of neuroma formation, 75 pigs were allocated to one of three treatments at birth: tail docked using clippers; tail docked using cautery iron; tail left intact. Tail docking was performed at 2 days of age and pigs were kept under conventional conditions until slaughter at 21 weeks of age. Tails were removed following slaughter and subjected to histological examination. Nerve histomorphology was scored according to the following scale: 1=discrete well-organised nerve bundles; 2=moderate neural proliferation and disorganisation affecting more than half of the circumference of the tail; 3=marked neural proliferation to form almost continuous disorganised bundles or non-continuous enlarged bundles compressing the surrounding connective tissue. Scores of 2 or 3 indicated neuroma formation. Scores were higher in docked pigs than undocked pigs (P<0.001), but did not differ between pigs docked using clippers and those docked using cautery (P=0.23). The results indicate that tail docking using either clippers or cautery results in neuroma formation, thus having the potential to affect long-term pig welfare.

  7. Initial speed of knots in the plasma tail of C/2013 R1(Lovejoy)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yagi, Masafumi; Furusho, Reiko; Terai, Tsuyoshi

    We report short-time variations in the plasma tail of C/2013 R1(Lovejoy). A series of short (2–3 minutes) exposure images with the 8.2 m Subaru telescope shows faint details of filaments and their motions over a 24 minute observing duration. We identified rapid movements of two knots in the plasma tail near the nucleus (∼3×10{sup 5} km). Their speeds are 20 and 25 km s{sup −1} along the tail and 3.8 and 2.2 km s{sup −1} across it, respectively. These measurements set a constraint on an acceleration model of plasma tail and knots as they set the initial speed just aftermore » their formation. We also found a rapid narrowing of the tail. After correcting the motion along the tail, the narrowing speed is estimated to be ∼8 km s{sup −1}. These rapid motions suggest the need for high time-resolution studies of comet plasma tails with a large telescope.« less

  8. Flight dynamics of a pterosaur-inspired aircraft utilizing a variable-placement vertical tail.

    PubMed

    Roberts, Brian; Lind, Rick; Chatterjee, Sankar

    2011-06-01

    Mission performance for small aircraft is often dependent on the turn radius. Various biologically inspired concepts have demonstrated that performance can be improved by morphing the wings in a manner similar to birds and bats; however, the morphing of the vertical tail has received less attention since neither birds nor bats have an appreciable vertical tail. This paper investigates a design that incorporates the morphing of the vertical tail based on the cranial crest of a pterosaur. The aerodynamics demonstrate a reduction in the turn radius of 14% when placing the tail over the nose in comparison to a traditional aft-placed vertical tail. The flight dynamics associated with this configuration has unique characteristics such as a Dutch-roll mode with excessive roll motion and a skid divergence that replaces the roll convergence.

  9. Microbially-accelerated consolidation of oil sands tailings. Pathway I: changes in porewater chemistry

    PubMed Central

    Siddique, Tariq; Kuznetsov, Petr; Kuznetsova, Alsu; Arkell, Nicholas; Young, Rozlyn; Li, Carmen; Guigard, Selma; Underwood, Eleisha; Foght, Julia M.

    2014-01-01

    Dispersed clay particles in mine tailings and soft sediments remain suspended for decades, hindering consolidation and challenging effective management of these aqueous slurries. Current geotechnical engineering models of self-weight consolidation of tailings do not consider microbial contribution to sediment behavior, however, here we show that microorganisms indigenous to oil sands tailings change the porewater chemistry and accelerate consolidation of oil sands tailings. A companion paper describes the role of microbes in alteration of clay chemistry in tailings. Microbial metabolism in mature fine tailings (MFT) amended with an organic substrate (hydrolyzed canola meal) produced methane (CH4) and carbon dioxide (CO2). Dissolution of biogenic CO2 lowered the pH of amended MFT to pH 6.4 vs. unamended MFT (pH 7.7). About 12% more porewater was recovered from amended than unamended MFT during 2 months of active microbial metabolism, concomitant with consolidation of tailings. The lower pH in amended MFT dissolved carbonate minerals, thereby releasing divalent cations including calcium (Ca2+) and magnesium (Mg2+) and increasing bicarbonate (HCO−3) in porewater. The higher concentrations increased the ionic strength of the porewater, in turn reducing the thickness of the diffuse double layer (DDL) of clay particles by reducing the surface charge potential (repulsive forces) of the clay particles. The combination of these processes accelerated consolidation of oil sands tailings. In addition, ebullition of biogenic gases created transient physical channels for release of porewater. In contrast, saturating the MFT with non-biogenic CO2 had little effect on consolidation. These results have significant implications for management and reclamation of oil sands tailings ponds and broad importance in anaerobic environments such as contaminated harbors and estuaries containing soft sediments rich in clays and organics. PMID:24711805

  10. Microbially-accelerated consolidation of oil sands tailings. Pathway I: changes in porewater chemistry.

    PubMed

    Siddique, Tariq; Kuznetsov, Petr; Kuznetsova, Alsu; Arkell, Nicholas; Young, Rozlyn; Li, Carmen; Guigard, Selma; Underwood, Eleisha; Foght, Julia M

    2014-01-01

    Dispersed clay particles in mine tailings and soft sediments remain suspended for decades, hindering consolidation and challenging effective management of these aqueous slurries. Current geotechnical engineering models of self-weight consolidation of tailings do not consider microbial contribution to sediment behavior, however, here we show that microorganisms indigenous to oil sands tailings change the porewater chemistry and accelerate consolidation of oil sands tailings. A companion paper describes the role of microbes in alteration of clay chemistry in tailings. Microbial metabolism in mature fine tailings (MFT) amended with an organic substrate (hydrolyzed canola meal) produced methane (CH4) and carbon dioxide (CO2). Dissolution of biogenic CO2 lowered the pH of amended MFT to pH 6.4 vs. unamended MFT (pH 7.7). About 12% more porewater was recovered from amended than unamended MFT during 2 months of active microbial metabolism, concomitant with consolidation of tailings. The lower pH in amended MFT dissolved carbonate minerals, thereby releasing divalent cations including calcium (Ca(2+)) and magnesium (Mg(2+)) and increasing bicarbonate (HCO(-) 3) in porewater. The higher concentrations increased the ionic strength of the porewater, in turn reducing the thickness of the diffuse double layer (DDL) of clay particles by reducing the surface charge potential (repulsive forces) of the clay particles. The combination of these processes accelerated consolidation of oil sands tailings. In addition, ebullition of biogenic gases created transient physical channels for release of porewater. In contrast, saturating the MFT with non-biogenic CO2 had little effect on consolidation. These results have significant implications for management and reclamation of oil sands tailings ponds and broad importance in anaerobic environments such as contaminated harbors and estuaries containing soft sediments rich in clays and organics.

  11. Metals uptake and health risks associated with cattle grazing on mine tailings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tsuji, J.S.

    1994-12-31

    Cattle are used at a site in Arizona to revegetate mine tailings dams by dispersing seeds and adding fertilizer with their manure. Although this program has been successful in revegetating the slopes, the residual metals in the tailings may potentially be accumulated by the cattle. Using US EPA guidelines on indirect exposure pathways and data on metals in tailings and in grasses, exposure and tissue levels of metals were calculated to assess health threats to the cattle or to those consuming the beef. Lead in the tailings and cadmium in tailings and grasses were selected for detailed exposure analysis viamore » ingestion of tailings and grasses by grazing cattle. Predicted exposures to cattle were below levels resulting in toxic effects to livestock. Estimated human exposures were below the EPA reference dose for cadmium even for a 15 kg child consuming beef or beef liver. Similarly, estimated tissue levels of lead were within reported background dietary levels of lead in beef and kidney. Necropsies of four newborn calves found no evidence of metal toxicity, but possible copper and selenium deficiencies combined with viral infection. Similarly, blood samples from pregnant cattle had non-detectable levels of lead, arsenic, and cadmium.« less

  12. Active Control of F/A-18 Vertical Tail Buffeting using Piezoelectric Actuators

    NASA Technical Reports Server (NTRS)

    Sheta, Essam F.; Moses, Robert W.; Huttsell, Lawerence J.; Harrand, Vincent J.

    2003-01-01

    Vertical tail buffeting is a serious multidisciplinary problem that limits the performance of twin-tail fighter aircraft. The buffet problem occurs at high angles of attack when the vortical flow breaks down ahead of the vertical tails resulting in unsteady and unbalanced pressure loads on the vertical tails. This paper describes a multidisciplinary computational investigation for buffet load alleviation of full F/A-18 aircraft using distributed piezoelectric actuators. The inboard and outboard surfaces of the vertical tail are equipped with piezoelectric actuators to control the buffet responses in the first bending and torsion modes. The electrodynamics of the smart structure are expressed with a three-dimensional finite element model. A single-input-single-output controller is designed to drive the active piezoelectric actuators. High-fidelity multidisciplinary analysis modules for the fluid dynamics, structure dynamics, electrodynamics of the piezoelectric actuators, fluid-structure interfacing, and grid motion are integrated into a multidisciplinary computing environment that controls the temporal synchronization of the analysis modules. Peak values of the power spectral density of tail tip acceleration are reduced by as much as 22% in the first bending mode and by as much as 82% in the first torsion mode. RMS values of tip acceleration are reduced by as much as 12%.

  13. The use of one- versus two-tailed tests to evaluate prevention programs.

    PubMed

    Ringwalt, Chris; Paschall, M J; Gorman, Dennis; Derzon, James; Kinlaw, Alan

    2011-06-01

    Investigators have used both one- and two-tailed tests to determine the significance of findings yielded by program evaluations. While the literature that addresses the appropriate use of each type of significance test should be used is historically inconsistent, almost all authorities now agree that one-tailed tests are rarely (if ever) appropriate. A review of 85 published evaluations of school-based drug prevention curricula specified on the National Registry of Effective Programs and Practices revealed that 20% employed one-tailed tests and, within this subgroup, an additional 4% also employed two-tailed tests. The majority of publications either did not specify the type of statistical test employed or used some other criterion such as effect sizes or confidence intervals. Evaluators reported that they used one-tailed tests either because they stipulated the direction of expected findings in advance, or because prior evaluations of similar programs had yielded no negative results. The authors conclude that one-tailed tests should never be used because they introduce greater potential for Type I errors and create an uneven playing field when outcomes are compared across programs. The authors also conclude that the traditional threshold of significance that places α at .05 is arbitrary and obsolete, and that evaluators should consistently report the exact p values they find.

  14. Diagnosis of Amyloidosis and Differentiation from Chronic, Idiopathic Enterocolitis in Rhesus (Macaca mulatta) and Pig-Tailed (M. nemestrina) Macaques

    PubMed Central

    Rice, Kelly A; Chen, Edward S; Pate, Kelly A Metcalf; Hutchinson, Eric K; Adams, Robert J

    2013-01-01

    Amyloidosis is a progressive and ultimately fatal disease in which amyloid, an insoluble fibrillar protein, is deposited inappropriately in multiple organs, eventually leading to organ dysfunction. Although this condition commonly affects macaques, there is currently no reliable method of early diagnosis. Changes in clinical pathology parameters have been associated with amyloidosis but occur in late stages of disease, are nonspecific, and resemble those seen in chronic, idiopathic enterocolitis. A review of animal records revealed that amyloidosis was almost always diagnosed postmortem, with prevalences of 15% and 25% in our rhesus and pig-tailed macaque colonies, respectively. As a noninvasive, high-throughput diagnostic approach to improve antemortem diagnosis of amyloidosis in macaques, we evaluated serum amyloid A (SAA), an acute-phase protein and the precursor to amyloid. Using necropsy records and ELISA analysis of banked serum, we found that SAA is significantly elevated in both rhesus and pig-tailed macaques with amyloid compared with those with chronic enterocolitis and healthy controls. At necropsy, 92% of rhesus and 83% of pig-tailed had amyloid deposition in either the intestines or liver. Minimally invasive biopsy techniques including endoscopy of the small intestine, mucosal biopsy of the colon, and ultrasound-guided trucut biopsy of the liver were used to differentiate macaques in our colonies with similar clinical presentations as either having amyloidosis or chronic, idiopathic enterocolitis. Our data suggest that SAA can serve as an effective noninvasive screening tool for amyloidosis and that minimally invasive biopsies can be used to confirm this diagnosis. PMID:23759529

  15. Development of a dust deposition forecast model for a mine tailings impoundment

    NASA Astrophysics Data System (ADS)

    Stovern, Michael

    Wind erosion, transport and deposition of particulate matter can have significant impacts on the environment. It is observed that about 40% of the global land area and 30% of the earth's population lives in semiarid environments which are especially susceptible to wind erosion and airborne transport of contaminants. With the increased desertification caused by land use changes, anthropogenic activities and projected climate change impacts windblown dust will likely become more significant. An important anthropogenic source of windblown dust in this region is associated with mining operations including tailings impoundments. Tailings are especially susceptible to erosion due to their fine grain composition, lack of vegetative coverage and high height compared to the surrounding topography. This study is focused on emissions, dispersion and deposition of windblown dust from the Iron King mine tailings in Dewey-Humboldt, Arizona, a Superfund site. The tailings impoundment is heavily contaminated with lead and arsenic and is located directly adjacent to the town of Dewey-Humboldt. The study includes in situ field measurements, computational fluid dynamic modeling and the development of a windblown dust deposition forecasting model that predicts deposition patterns of dust originating from the tailings impoundment. Two instrumented eddy flux towers were setup on the tailings impoundment to monitor the aeolian and meteorological conditions. The in situ observations were used in conjunction with a computational fluid dynamic (CFD) model to simulate the transport of windblown dust from the mine tailings to the surrounding region. The CFD model simulations include gaseous plume dispersion to simulate the transport of the fine aerosols, while individual particle transport was used to track the trajectories of larger particles and to monitor their deposition locations. The CFD simulations were used to estimate deposition of tailings dust and identify topographic mechanisms

  16. Riparian shrub metal concentrations and growth in amended fluvial mine tailings

    USDA-ARS?s Scientific Manuscript database

    Fluvial mine tailing deposition has caused extensive riparian damage throughout the western United States. Willows are often used for fluvial mine tailing revegetation, but some species accumulate excessive metal concentrations which could be detrimental to browsers. In a greenhouse experiment, gr...

  17. Grasping convergent evolution in syngnathids: a unique tale of tails.

    PubMed

    Neutens, C; Adriaens, D; Christiaens, J; De Kegel, B; Dierick, M; Boistel, R; Van Hoorebeke, L

    2014-06-01

    Seahorses and pipehorses both possess a prehensile tail, a unique characteristic among teleost fishes, allowing them to grasp and hold onto substrates such as sea grasses. Although studies have focused on tail grasping, the pattern of evolutionary transformations that made this possible is poorly understood. Recent phylogenetic studies show that the prehensile tail evolved independently in different syngnathid lineages, including seahorses, Haliichthys taeniophorus and several types of so-called pipehorses. This study explores the pattern that characterizes this convergent evolution towards a prehensile tail, by comparing the caudal musculoskeletal organization, as well as passive bending capacities in pipefish (representing the ancestral state), pipehorse, seahorse and H. taeniophorus. To study the complex musculoskeletal morphology, histological sectioning, μCT-scanning and phase contrast synchrotron scanning were combined with virtual 3D-reconstructions. Results suggest that the independent evolution towards tail grasping in syngnathids reflects at least two quite different strategies in which the ancestral condition of a heavy plated and rigid system became modified into a highly flexible one. Intermediate skeletal morphologies (between the ancestral condition and seahorses) could be found in the pygmy pipehorses and H. taeniophorus, which are phylogenetically closely affiliated with seahorses. This study suggests that the characteristic parallel myoseptal organization as already described in seahorse (compared with a conical organization in pipefish and pipehorse) may not be a necessity for grasping, but represents an apomorphy for seahorses, as this pattern is not found in other syngnathid species possessing a prehensile tail. One could suggest that the functionality of grasping evolved before the specialized, parallel myoseptal organization seen in seahorses. However, as the grasping system in pipehorses is a totally different one, this cannot be

  18. Grasping convergent evolution in syngnathids: a unique tale of tails

    PubMed Central

    Neutens, C; Adriaens, D; Christiaens, J; De Kegel, B; Dierick, M; Boistel, R; Van Hoorebeke, L

    2014-01-01

    Seahorses and pipehorses both possess a prehensile tail, a unique characteristic among teleost fishes, allowing them to grasp and hold onto substrates such as sea grasses. Although studies have focused on tail grasping, the pattern of evolutionary transformations that made this possible is poorly understood. Recent phylogenetic studies show that the prehensile tail evolved independently in different syngnathid lineages, including seahorses, Haliichthys taeniophorus and several types of so-called pipehorses. This study explores the pattern that characterizes this convergent evolution towards a prehensile tail, by comparing the caudal musculoskeletal organization, as well as passive bending capacities in pipefish (representing the ancestral state), pipehorse, seahorse and H. taeniophorus. To study the complex musculoskeletal morphology, histological sectioning, μCT-scanning and phase contrast synchrotron scanning were combined with virtual 3D-reconstructions. Results suggest that the independent evolution towards tail grasping in syngnathids reflects at least two quite different strategies in which the ancestral condition of a heavy plated and rigid system became modified into a highly flexible one. Intermediate skeletal morphologies (between the ancestral condition and seahorses) could be found in the pygmy pipehorses and H. taeniophorus, which are phylogenetically closely affiliated with seahorses. This study suggests that the characteristic parallel myoseptal organization as already described in seahorse (compared with a conical organization in pipefish and pipehorse) may not be a necessity for grasping, but represents an apomorphy for seahorses, as this pattern is not found in other syngnathid species possessing a prehensile tail. One could suggest that the functionality of grasping evolved before the specialized, parallel myoseptal organization seen in seahorses. However, as the grasping system in pipehorses is a totally different one, this cannot be

  19. A study of bauxite tailing quality improvement by reverse flotation

    NASA Astrophysics Data System (ADS)

    Wulandari, W.; Purwasasmita, M.; Sanwani, E.; Malatsih, W.; Fadilla, F.

    2018-01-01

    The pre-treatment of bauxite ore from Tayan, West Kalimantan includes washing and screening fine bauxite particles (-2mm) prior as the feed to the Bayer process for producing alumina. These fine particles are believed to have high content of silica which is detrimental to the process. This washed bauxite tailing still has a significant amount of alumina content. Previous research has indicated that bauxite ore can be upgraded by applying reverse flotation method to reduce its silica content in the ore. Therefore, this study is aimed to utilize reverse flotation method to recover alumina content from washed bauxite tailing. The reverse flotation experiments were carried out at pH of 6 and 8; while the particle sizes were varied at - 140+270 mesh and -270 mesh, using a batch and circuit configuration. The result of this study shows that the batch reverse flotation can recover alumina in the tailing up to 81.4%, however the silica content is still significant. The complexity of silica-alumina minerals in the tailing prevents a complete separation of the ores by only using reverse flotation.

  20. Aerodynamics of a Flapping Airfoil with a Flexible Tail

    NASA Astrophysics Data System (ADS)

    Lai, Alan Kai San

    This dissertation presents computational solutions to an airfoil in a oscillatory heaving motion with a aeroelastically flexible tail attachment. An unsteady potential flow solver is coupled to a structural solver to obtain the aeroelastic flow solution over an inviscid fluid to investigate the propulsive performance of such a configuration. The simulation is then extended to a two-dimensional viscous solver by coupling NASA's CFL3D solver to the structural solver to study how the flow is altered by the presence of viscosity. Finally, additional simulations are done in three dimensions over wings with varying aspect ratio to study the three-dimensional effects on the propulsive performance of an airfoil with an aeroelastic tail. The computation reveals that the addition of the aeroelastic trailing edge improved the thrust generated by a heaving airfoil significantly. As the frequency of the heaving motion increases, the thrust generated by the airfoil with the tail increases exponentially. In an inviscid fluid, the increase in thrust is insufficient to overcome the increase in power required to maintain the motion and as a result the overall propulsive efficiency is reduced. When the airfoil is heaving in a viscous fluid, the presence of a suction boundary layer and the appearance of leading edge vortex increase the thrust generated to such an extent that the propulsive efficiency is increased by about 3% when compared to the same airfoil with a rigid tail. The three-dimensional computations shows that the presence of the tip vorticies suppress some of the increase in thrust observed in the two-dimensional viscous computations for short span wings. For large span wings, the overall thrust enhancing capabilities of the aeroelastic tail is preserved.

  1. Weighted Kolmogorov-Smirnov test: accounting for the tails.

    PubMed

    Chicheportiche, Rémy; Bouchaud, Jean-Philippe

    2012-10-01

    Accurate goodness-of-fit tests for the extreme tails of empirical distributions is a very important issue, relevant in many contexts, including geophysics, insurance, and finance. We have derived exact asymptotic results for a generalization of the large-sample Kolmogorov-Smirnov test, well suited to testing these extreme tails. In passing, we have rederived and made more precise the approximate limit solutions found originally in unrelated fields, first in [L. Turban, J. Phys. A 25, 127 (1992)] and later in [P. L. Krapivsky and S. Redner, Am. J. Phys. 64, 546 (1996)].

  2. Controlled chaos: three-dimensional kinematics, fiber histochemistry, and muscle contractile dynamics of autotomized lizard tails.

    PubMed

    Higham, Timothy E; Lipsett, Kathryn R; Syme, Douglas A; Russell, Anthony P

    2013-01-01

    The ability to shed an appendage occurs in both vertebrates and invertebrates, often as a tactic to avoid predation. The tails of lizards, unlike most autotomized body parts of animals, exhibit complex and vigorous movements once disconnected from the body. Despite the near ubiquity of autotomy across groups of lizards and the fact that this is an extraordinary event involving the self-severing of the spinal cord, our understanding of why and how tails move as they do following autotomy is sparse. We herein explore the histochemistry and physiology of the tail muscles of the leopard gecko (Eublepharis macularius), a species that exhibits vigorous and variable tail movements following autotomy. To confirm that the previously studied tail movements of this species are generally representative of geckos and therefore suitable for in-depth muscle studies, we quantified the three-dimensional kinematics of autotomized tails in three additional species. The movements of the tails of all species were generally similar and included jumps, flips, and swings. Our preliminary analyses suggest that some species of gecko exhibit short but high-frequency movements, whereas others exhibit larger-amplitude but lower-frequency movements. We then compared the ATPase and oxidative capacity of muscle fibers and contractile dynamics of isolated muscle bundles from original tails, muscle from regenerate tails, and fast fibers from an upper limb muscle (iliofibularis) of the leopard gecko. Histochemical analysis revealed that more than 90% of the fibers in original and regenerate caudal muscles had high ATPase but possessed a superficial layer of fibers with low ATPase and high oxidative capacity. We found that contraction kinetics, isometric force, work, power output, and the oscillation frequency at which maximum power was generated were lowest in the original tail, followed by the regenerate tail and then the fast fibers of the iliofibularis. Muscle from the original tail exhibited

  3. High resolution flow field prediction for tail rotor aeroacoustics

    NASA Technical Reports Server (NTRS)

    Quackenbush, Todd R.; Bliss, Donald B.

    1989-01-01

    The prediction of tail rotor noise due to the impingement of the main rotor wake poses a significant challenge to current analysis methods in rotorcraft aeroacoustics. This paper describes the development of a new treatment of the tail rotor aerodynamic environment that permits highly accurate resolution of the incident flow field with modest computational effort relative to alternative models. The new approach incorporates an advanced full-span free wake model of the main rotor in a scheme which reconstructs high-resolution flow solutions from preliminary, computationally inexpensive simulations with coarse resolution. The heart of the approach is a novel method for using local velocity correction terms to capture the steep velocity gradients characteristic of the vortex-dominated incident flow. Sample calculations have been undertaken to examine the principal types of interactions between the tail rotor and the main rotor wake and to examine the performance of the new method. The results of these sample problems confirm the success of this approach in capturing the high-resolution flows necessary for analysis of rotor-wake/rotor interactions with dramatically reduced computational cost. Computations of radiated sound are also carried out that explore the role of various portions of the main rotor wake in generating tail rotor noise.

  4. Foraging behavior of Long-tailed Ducks in a ferry wake

    USGS Publications Warehouse

    Perry, Matthew C.

    2012-01-01

    Clangula hyemalis (Long-tailed Ducks) were observed diving in the wake of the Nantucket Island ferry during December over a 5-year period (2005–2009). The unusual diving behavior appeared to be related to foraging, but could not be confirmed. Long-tailed Ducks typically feed on more mobile prey than most other diving ducks, and it is speculated that the propeller wash in shallow water dislodged or disturbed prey and provided an enhanced feeding opportunity. Long-tailed Ducks collected while feeding in a disturbed area near a clamming boat not far from the ferry channel were feeding predominantly on Crangon septemspinosa (Sand Shrimp) that apparently had been dislodged by the clamming operation.

  5. Numerical modeling of cracking pattern's influence on the dynamic response of thickened tailings disposals: a periodic approach

    NASA Astrophysics Data System (ADS)

    Ferrer, Gabriel; Sáez, Esteban; Ledezma, Christian

    2018-01-01

    Copper production is an essential component of the Chilean economy. During the extraction process of copper, large quantities of waste materials (tailings) are produced, which are typically stored in large tailing ponds. Thickened Tailings Disposal (TTD) is an alternative to conventional tailings ponds. In TTD, a considerable amount of water is extracted from the tailings before their deposition. Once a thickened tailings layer is deposited, it loses water and it shrinks, forming a relatively regular structure of tailings blocks with vertical cracks in between, which are then filled up with "fresh" tailings once the new upper layer is deposited. The dynamic response of a representative column of this complex structure made out of tailings blocks with softer material in between was analyzed using a periodic half-space finite element model. The tailings' behavior was modeled using an elasto-plastic multi-yielding constitutive model, and Chilean earthquake records were used for the seismic analyses. Special attention was given to the liquefaction potential evaluation of TTD.

  6. Analysis of the effects of wing interference on the tail contributions to the rolling derivatives

    NASA Technical Reports Server (NTRS)

    Michael, William H , Jr

    1952-01-01

    An analysis of the effects of wing interference on the tail contributions to the rolling stability derivatives of complete airplane configurations is made by calculating the angularity of the air stream at the vertical tail due to rolling and determining the resulting forces and moments. Some of the important factors which affect the resultant angularity on the vertical tail are wing aspect ratio and sweepback, vertical-tail span, and considerations associated with angle of attack and airplane geometry. Some calculated sidewash results for a limited range of plan forms and vertical-tail sizes are presented. Equations taking into account the sidewash results are given for determining the tail contributions to the rolling derivatives. Comparisons of estimated and experimental results indicate that a consideration of wing interference effects improves the estimated values of the tail contributions to the rolling derivatives and that fair agreement with available experimental data is obtained.

  7. Morphologic and morphometric evaluation of pancreatic islets in chronic Chagas' disease.

    PubMed

    Saldanha, J C; dos Santos, V M; dos Reis, M A; da Cunha, D F; Antunes Teixeira, V P

    2001-01-01

    Hyperglycemia and abnormal glucose tolerance tests observed in some patients with chronic Chagas' disease suggest the possibility of morphological changes in pancreatic islets and/or denervation. The purpose of this study was to describe the morphology and morphometry of pancreatic islets in chronic Chagas' disease. Morphologic and computerized morphometric studies were performed in fragments of the head, body, and tail regions of the pancreas obtained at necropsies of 8 normal controls and 17 patients with chronic Chagas' disease: 8 with the digestive form (Megas) and 9 with the congestive heart failure form. The Megas group had a larger (p < 0.05) pancreatic islet area in the tail of the pancreas (10649.3 +/- 4408.8 micrometer2) than the normal control (9481.8 +/- 3242.4 micrometer2) and congestive heart failure (9475.1 +/- 2104.9 micrometer2) groups; likewise, the density of the pancreatic islets (PI) was greater (1.2 +/- 0.7 vs. 0.9 +/- 0.6 vs. 1.9 +/- 1.0 PI/mm2, respectively). In the tail region of the pancreas of patients with the Megas form, there was a significant and positive correlation (r = +0.73) between the area and density of pancreatic islets. Discrete fibrosis and leukocytic infiltrates were found in pancreatic ganglia and pancreatic islets of the patients with Chagas' disease. Trypanosoma cruzi nests were not observed in the examined sections. Individuals with the Megas form of Chagas' disease showed increased area and density of pancreatic islets in the tail of the pancreas. The observed morphometric and morphologic alterations are consistent with functional changes in the pancreas, including glycemia and insulin disturbances.

  8. Young calcareous soil chronosequences as a model for ecological restoration on alkaline mine tailings.

    PubMed

    Cross, Adam T; Lambers, Hans

    2017-12-31

    Tailings are artificial soil-forming substrates that have not been created by the natural processes of soil formation and weathering. The extreme pH environment and corresponding low availability of some macro- and micronutrients in alkaline tailings, coupled with hostile physical and geochemical conditions, present a challenging environment to native biota. Some significant nutritional constraints to ecosystem reconstruction on alkaline tailings include i) predominant or complete absence of combined nitrogen (N) and poor soil N retention; ii) the limited bioavailability of some micronutrients at high soil pH (e.g., Mn, Fe, Zn and Cu); and iii) potentially toxic levels of biologically available soil phosphorus (P) for P-sensitive plants. The short regulatory time frames (years) for mine closure on tailings landforms are at odds with the long time required for natural pedogenic processes to ameliorate these factors (thousands of years). However, there are similarities between the chemical composition and nutrient status of alkaline tailings and the poorly-developed, very young calcareous soils of biodiverse regions such as south-western Australia. We propose that basic knowledge of chronosequences that start with calcareous soils may provide an informative model for understanding the pedogenic processes required to accelerate soil formation on tailings. Development of a functional, stable root zone is crucial to successful ecological restoration on tailings, and three major processes should be facilitated as early as possible during processing or in the early stages of restoration to accelerate soil development on alkaline tailings: i) acidification of the upper tailings profile; ii) establishment of appropriate and resilient microbial communities; and iii) the early development of appropriate pioneer vegetation. Achieving successful ecological restoration outcomes on tailings landforms is likely one of the greatest challenges faced by restoration ecologists and the

  9. Chronic Wasting Disease

    USGS Publications Warehouse

    Richards, Bryan

    2007-01-01

    Chronic wasting disease (CWD) is an always-fatal, neurological illness occurring in North American cervids (members of the deer family), including white-tailed deer, mule deer, elk and moose. Since its discovery in 1967, CWD has spread geographically and increased in prevalence locally. CWD is contagious; it can be transmitted freely within and among free-ranging populations. It is likely that diseased animals can transmit CWD to healthy animals long before they become clinically ill. Managing CWD in free-ranging populations is extremely difficult, therefore preventative measures designed to reduce the chance for disease spread are critically important.

  10. Female white-tailed deer survival across ecoregions in Minnesota and South Dakota

    USGS Publications Warehouse

    Grovenburg, T.W.; Swanson, C.C.; Jacques, C.N.; Deperno, C.S.; Klaver, R.W.; Jenks, J.A.

    2011-01-01

    Survival and cause-specific mortality of female white-tailed deer (Odocoileus virginianus) have been well documented in forested and agricultural landscapes, but limited information has been collected in grassland habitats typical of the Northern Great Plains. Our objectives were to document and compare survival and cause-specific mortality of adult female white-tailed deer in four distinct ecoregions. We captured and radiocollared 190 (159 adult, 31 yearling) female white-tailed deer and monitored (including deer from a previous study) a total of 246 (215 adult, 31 yearling) deer from Jan. 2000 to Dec. 2007. We documented 113 mortalities; hunting (including wounding loss) accounted for 69.9% of all mortalities and vehicle collisions accounted for an additional 15.0%. Natural causes (e.g., disease, predation) of mortality were minor compared to human-related causes (e.g., hunting, vehicle collisions). We used known fate modeling in program MARK to estimate survival rates and compare ecoregions and seasons. Model {Sseason (winter = summer)} had the lowest AICc value suggesting that survival differed only between seasons where winter and summer survival was equal and differed with fall season. Annual and seasonal (summer, fall, winter) survival rates using the top model {Sseason (summer = winter)} were 0.76 (95% ci  =  0.70–0.80), 0.97 (95% ci  =  0.96–0.98), 0.80 (95% ci  =  0.76–0.83) and 0.97 (95% ci  =  0.96–0.98), respectively. High human-related mortality was likely associated with limited permanent cover, extensive road networks and high hunter density. Deer management in four distinct ecoregions relies on hunter harvest to maintain deer populations within state management goals.

  11. Techniques for Nonterminal Blood Sampling in Black-Tailed Prairie Dogs (Cynomys ludovicianus).

    PubMed

    Head, Valerie; Eshar, David; Nau, Melissa R

    2017-03-01

    Black-tailed prairie dogs (Cynomys ludovicianus) are used as an animal model for research on gallbladder stones and several infectious diseases. A comprehensive, instructive resource regarding the appropriate techniques for venipuncture and collection of nonterminal blood samples in this species has not yet been published. Blood samples (1 mL or larger) were readily obtained from the jugular vein, femoral vein, or cranial vena cava, whereas peripheral sites, such as the cephalic vein, saphenous vein, and tarsal vein, mainly were useful for obtaining smaller volumes. The detailed and illustrated information presented here can aid clinicians and researchers in performing venipuncture, anesthesia, and handling of this species.

  12. Tail Biting Trellis Representation of Codes: Decoding and Construction

    NASA Technical Reports Server (NTRS)

    Shao. Rose Y.; Lin, Shu; Fossorier, Marc

    1999-01-01

    This paper presents two new iterative algorithms for decoding linear codes based on their tail biting trellises, one is unidirectional and the other is bidirectional. Both algorithms are computationally efficient and achieves virtually optimum error performance with a small number of decoding iterations. They outperform all the previous suboptimal decoding algorithms. The bidirectional algorithm also reduces decoding delay. Also presented in the paper is a method for constructing tail biting trellises for linear block codes.

  13. Flight investigation of the effect of tail boom strakes on helicopter directional control

    NASA Technical Reports Server (NTRS)

    Kelly, Henry L.; Crowell, Cynthia A.; Yenni, Kenneth R.; Lance, Michael B.

    1993-01-01

    A joint U.S. Army/NASA flight investigation was conducted utilizing a single-rotor helicopter to determine the effectiveness of horizontally mounted tail boom strakes on directional controllability and tail rotor power during low-speed, crosswind operating conditions. Three configurations were investigated: (1) baseline (strakes off), (2) single strake (strake at upper shoulder on port side of boom), and (3) double strake (upper strake plus a lower strake on same side of boom). The strakes were employed as a means to separate airflow over the tail boom and change fuselage yawing moments in a direction to improve the yaw control margin and reduce tail rotor power. Crosswind data were obtained in 5-knot increments of airspeed from 0 to 35 knots and in 30 deg increments of wind azimuth from 0 deg to 330 deg. At the most critical wind azimuth and airspeed in terms of tail rotor power, the strakes improved the pedal margin by 6 percent of total travel and reduced tail rotor power required by 17 percent. The increase in yaw control and reduction in tail rotor power offered by the strakes can expand the helicopter operating envelope in terms of gross weight and altitude capability. The strakes did not affect the flying qualities of the vehicle at airspeeds between 35 and 100 knots.

  14. Assessing Natural Radionuclide Migration in the Legacy Tailings of Uranium Production

    NASA Astrophysics Data System (ADS)

    Bondarenko, G.; Koliabina, I.; Marinich, O.

    2011-12-01

    The former Prydniprovsky Chemical Plant in Dniprodzerzhynsk, Ukraine, processed uranium ore from 1949 until 1991. Multiple tailing ponds containing solid residual waste products from the uranium leaching and processing of uranium were accumulated along the Dnieper River, including the largest, adjacent to the Dnieper Reservoir, containing over 12 million tons of tailings. Samples for this study were selected from a core recovered from the Dnieper tailing pit in 2009, and used to assess radionuclide migration from tailing ponds. Samples were selected from different depths of the tailing pit core, analyzed for total radionuclide concentrations [Marinich et al., 2009], and successively leached using distilled water, followed by 1N ammonium acetate solution, and finally by 1N HCl solution. Leaching times were ~24 h at 15.17 °C. 238U, 230Th and 226Ra leachate activities were measured by γ-spectrometry with a Ge(Li) detector. 210Pb activity was measured using a SEB-01 scintillation β-spectrometer. Errors depended on measuring method, radionuclide, activity and exposure time: 238U, 11.9%; 230Th, 10.9%; 226Ra, 9.3%; 210Pb ~30%. The average total 238U activity in the tailing profile was 4 Bq/g. The concentration of 238U in the water leachates increased with depth from 14.5% (7-7.5 m), to 43% (11-11.5 m). The concentration of 238U in the acid leachates behaved similarly, increasing from 5.5 % to 15.5% with depth. While the total 230Th activity in increased from 30 Bq/g (7-7.5 m) to 540 Bq/g (11-11.5 m), the 230Th concentration in ammonium acetate leachates decreased from ˜15% to ˜1%. The concentration of 226Ra in all leachates was <1%, indicating that, under conditions of the Dnieper tailing pit, 226Ra is essentially immobile. The concentration of 210Pb in the leachates was as high as 10%. In general, the magnitude of mobile activity from the Dnieper tailing pit core samples decreases in the order 238U>230Th≥210Pb> 226Ra. Secular radioactive equilibrium in the 238U

  15. Chemical and ecotoxicity evaluation of tailings rehabilitated using Technosol

    NASA Astrophysics Data System (ADS)

    Arán, Diego; Santos, Erika S.; Abreu, Maria Manuela; Macías, Felipe

    2017-04-01

    The Fé mining area was the most important uranium deposit in Spain. In this deposit, the uranium mineralization contains sulfides. Consequently, tailings are a source of polymetallic contamination requiring their rehabilitation in order to decrease the dispersion of potentially hazardous elements (PHEs). The main objective of this work is to evaluate the efficiency of a Technosol application on the rehabilitation of these tailings at chemical and ecotoxicological level. In the field, a layer of 20 cm Technosol with andic and eutrophic characteristic was applied over the tailing (total area: 625 m2). After 20 months, composite samples of Technosol (TEC), recovered tailing (bottom of the Technosol, RT) and tailings without recuperation (T) were collected. These samples were characterized for pH, electric conductivity (EC), PHEs concentration in total fraction and available fraction extracted with rhizosphere-based method. Ecotoxicity bioassays were carried out with two species, Lollium perenne and Trifolium pratense following OECD Guidelines. Three bioassays were carried out: filter paper test and hydroponic test with leachates, and soil test. In leachates (extracted with DIN method) were determined pH, EC and same PHEs than in Technosol/Tailings. Visual aspects, germination, root and shoot elongation and dry biomass were evaluated. The substrate effect on growth of both species was evaluated in pot experiment (500 g Technosol/Tailings per pot, 70% of water-holding capacity) under greenhouse conditions after 69 days by dry shoot biomass. Materials from T had pH 4, EC: 1.2 mS/cm and high total concentrations of several PHEs (g/kg; Al: 46.2; As, Co and Pb: 0.02-0.03; Cu: 0.04; Fe: 63.2 Mn: 1.3; Ni and Zn: 0.1-0.2). However, PHEs concentrations in leachates and available fraction corresponded to <2.5% of total concentrations, except for Co, Mn and Ni where 7-18% of their total concentrations can be available to organisms. Leachates from RT showed a significant

  16. Summary of the engineering assessment of inactive uranium mill tailings, Durango Site, Durango, Colorado

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1981-06-01

    Ford, Bacon and Davis Utah Inc. has reevaluated the Durango site in order to revise the November 1977 engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at Durango, Colorado. This engineering assessment has included the preparation of topographic measurements sufficient to determine areas and volumes of tailings and radiation exposures of individuals and nearby populations, the investigations of site hydrology and meteorology, and the evaluation and costing of alternative corrective actions. Radon gas released from the nearly 1.6 million tons of tailings at the Durango site constitutes the most significant environmental impact, although windblownmore » tailings and external gamma radiation also are factors. The four alternative actions presented in this engineering assessment range from millsite and off-site decontamination with the addition of 3 m of stabilization cover material (Option I), to removal of the tailings to remote disposal sites and decontamination of the tailings site (Options II through IV). Cost estimates for the seven options range from about $10,700,000 for stabilization in-place, to about $21,800,000 for disposal at a distance of about 10 mi. Three principal alternatives for the reprocessing of the Durango tailings were examined: (a) heap leaching; (b) treatment at an existing mill; and (c) reprocessing at a new conventional mill constructed for tailings reprocessing.« less

  17. Subpart W: National Emission Standards for Radon Emissions From Operating Mill Tailings

    EPA Pesticide Factsheets

    Subpart W limits the radon-222 emissions rate from uranium tailings piles to 20 picocuries per square meter per second and requires that new tailings impoundments meet certain work practice standards.

  18. Acaricidal Treatment of White-Tailed Deer to Control Ixodes Scapularis (Acari: Ixodidae) in a New York Lyme Disease-Endemic Community

    USDA-ARS?s Scientific Manuscript database

    The 4-Poster device for the topical treatment of white-tailed deer, Odocoileus virginianus (Zimmermann) against ticks using the acaricide amitraz was evaluated in a Lyme borreliosis endemic community in Connecticut. As part of a 5-year project from 1997 to 2002, 21–24 of the 4-Posters were distribut...

  19. Flight Tests of Various Tail Modifications on the Brewster XSBA-1 Airplane II : Measurements of Flying Qualities with Tail Configuration Number Two

    NASA Technical Reports Server (NTRS)

    Phillips, W.H.; Crane, H.L.

    1943-01-01

    Several tail modifications of the Brewster XSBA-1 scout-bomber were investigated and results compared. Modifications consisted of variation of the chord of the elevator and rudder while the total area of the surfaces is kept constant and variations of the total area of the vertical tail surface. Configuration number 2 reduced trim changes by 50 percent and reduced average elevator control force gradient from 30 to 27 pounds/g. Stick travel required to stall in maneuver was 4.6 inches.

  20. Understanding the heavy-tailed dynamics in human behavior

    NASA Astrophysics Data System (ADS)

    Ross, Gordon J.; Jones, Tim

    2015-06-01

    The recent availability of electronic data sets containing large volumes of communication data has made it possible to study human behavior on a larger scale than ever before. From this, it has been discovered that across a diverse range of data sets, the interevent times between consecutive communication events obey heavy-tailed power law dynamics. Explaining this has proved controversial, and two distinct hypotheses have emerged. The first holds that these power laws are fundamental, and arise from the mechanisms such as priority queuing that humans use to schedule tasks. The second holds that they are statistical artifacts which only occur in aggregated data when features such as circadian rhythms and burstiness are ignored. We use a large social media data set to test these hypotheses, and find that although models that incorporate circadian rhythms and burstiness do explain part of the observed heavy tails, there is residual unexplained heavy-tail behavior which suggests a more fundamental cause. Based on this, we develop a quantitative model of human behavior which improves on existing approaches and gives insight into the mechanisms underlying human interactions.

  1. Modeling hydrological controls on variations in peat water content, water table depth, and surface energy exchange of a boreal western Canadian fen peatland

    NASA Astrophysics Data System (ADS)

    Mezbahuddin, M.; Grant, R. F.; Flanagan, L. B.

    2016-08-01

    Improved predictive capacity of hydrology and surface energy exchange is critical for conserving boreal peatland carbon sequestration under drier and warmer climates. We represented basic processes for water and O2 transport and their effects on ecosystem water, energy, carbon, and nutrient cycling in a process-based model ecosys to simulate effects of seasonal and interannual variations in hydrology on peat water content, water table depth (WTD), and surface energy exchange of a Western Canadian fen peatland. Substituting a van Genuchten model (VGM) for a modified Campbell model (MCM) in ecosys enabled a significantly better simulation of peat moisture retention as indicated by higher modeled versus measured R2 and Willmot's index (d) with VGM (R2 0.7, d 0.8) than with MCM (R2 0.25, d 0.35) for daily peat water contents from a wetter year 2004 to a drier year 2009. With the improved peat moisture simulation, ecosys modeled hourly WTD and energy fluxes reasonably well (modeled versus measured R2: WTD 0.6, net radiation 0.99, sensible heat >0.8, and latent heat >0.85). Gradually declining ratios of precipitation to evapotranspiration and of lateral recharge to discharge enabled simulation of a gradual drawdown of growing season WTD and a consequent peat drying from 2004 to 2009. When WTD fell below a threshold of 0.35 m below the hollow surface, intense drying of mosses in ecosys caused a simulated reduction in evapotranspiration and an increase in Bowen ratio during late growing season that were consistent with measurements. Hence, using appropriate water desorption curve coupled with vertical-lateral hydraulic schemes is vital to accurately simulate peatland hydrology and energy balance.

  2. BATSE Observations of Gamma-Ray Burst Tails

    NASA Technical Reports Server (NTRS)

    Connaughton, Valerie; Six, N. Frank (Technical Monitor)

    2001-01-01

    With the discovery of low-energy radiation appearing to come from the site of gamma-ray bursts in the hours to weeks after the initial burst of gamma rays, it would appear that astronomers have seen a cosmological imprint made by the burster on its surroundings. I discuss in this paper the phenomenon of post-burst emission in BATSE (Burst and Transient Source Experiment) gamma-ray bursts at energies traditionally associated with prompt emission. By summing the background-subtracted signals from hundreds of bursts, I find that tails out to hundreds of seconds after the trigger may be a common feature of long events (duration greater than 2s), and perhaps of the shorter bursts at a lower and shorter-lived level. The tail component appears independent of both the duration (within the long GRB sample) and brightness of the prompt burst emission, and may be softer. Some individual bursts have visible tails at gamma-ray energies and the spectrum in at least a few cases is different from that of the prompt emission. Afterglow at lower energies was detected for one of these bursts, GRB-991216, raising the possibility of afterglow observations over large energy ranges using the next generation of GRB detectors in conjunction with sensitive space or ground-based telescopes.

  3. BATSE Observations of Gamma-Ray Burst Tails

    NASA Technical Reports Server (NTRS)

    Connaughton, Valerie

    2002-01-01

    With the observation of low-energy radiation coming from the site of gamma-ray bursts in the hours to weeks after the initial gamma ray burst, it appears that astronomers have discovered a cosmological imprint made by the burster on its surroundings. This paper discusses the phenomenon of postburst emission in Burst and Transient Source Experiment (BATSE) gamma-ray bursts at energies usually associated with prompt emission. After summing up the background-subtracted signals from hundreds of bursts, it is found that tails out to hundreds of seconds after the trigger could be a common feature of events of a duration greater than 2 seconds, and perhaps of the shorter bursts at a lower and shorter-lived level. The tail component may be softer and seems independent of the duration (within the long-GRB sample) and brightness of the prompt burst emission. Some individual bursts have visible tails at gamma-ray energies, and the spectrum in a few cases differs from that of the prompt emission. For one of these bursts, GRB 991216, afterglow at lower energies was detected, which raised the possibility of seeing afterglow observations over large energy ranges using the next generation of GRB detectors in addition to sensitive space- or ground-based telescopes.

  4. Breeding biology and nest-site selection of red-tailed hawks in an altered desert grassland

    USGS Publications Warehouse

    Hobbs, R.J.; DeStefano, S.; Halvorson, W.L.

    2006-01-01

    Red-tailed Hawks (Buteo jamaicensis) have expanded their range as trees have invaded formerly-open grasslands. Desert grasslands of southern Arizona have been invaded by mesquite trees (Prosopis velutina) since Anglo-American settlement and now support a large population of Red-tailed Hawks. We studied a population of Red-tailed Hawks in an altered desert grassland in southern Arizona. Our objectives were to determine what environmental characteristics influence Red-tailed Hawk habitat selection in mesquite-invaded desert grasslands and to evaluate the habitat quality of these grasslands for Red-tailed Hawks based on nesting density, nest success, and productivity. Red-tailed Hawks had 86% (95% C.I. = 73-99) nest success and 1.82 young per breeding pair (95% C.I. = 1.41-2.23). Nesting density was 0.15 (95% CI = 0.08-0.21) breeding pairs/km2 and the mean nearest-neighbor distance was 1.95 km (95% C.I. = 1.74-2.16). Red-tailed Hawks selected nest-sites with taller nest-trees and greater tree height and cover than were available at random. Mesquite trees in desert grasslands provide abundant potential nesting structures for Red-tailed Hawks. ?? 2006 The Raptor Research Foundation, Inc.

  5. Decision solution, data manipulation and trust: The (un-)willingness to donate organs in Germany in critical times.

    PubMed

    Schwettmann, Lars

    2015-07-01

    In 2011 and 2012 a change of rules and a data-manipulation scandal focused German public attention on organ donation. This increased citizens' background knowledge as well as their willingness to respond to surveys. The present study is an effort to seize this research opportunity and to create evidence on which policy recommendations can be conceivably based. It uses data from two major representative surveys from 2011 to 2012 to address four central questions: Which characteristics, experiences and attitudes correlate with the written or unwritten willingness of individuals to donate (WTD) their own organs post-mortem? How has the WTD changed over time? To what extent does the WTD depend on normative trust? Which factors correlate with trust? The data is analyzed through summary statistics and regression models. Several hypotheses regarding factors connected with the WTD are confirmed in the survey results. Altruistic motives, relevant knowledge and trust are decisive. The special role of trust is corroborated by the data. As current German politics prevents the introduction of post-mortem donation incentives, potential policy making proposals are restricted to institutional changes to regain trust including the implementation of an organ donor registry and the advancement of counselling talks with general practitioners. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  6. Plants from the abandoned Nacozari mine tailings: evaluation of their phytostabilization potential.

    PubMed

    Santos, Alina E; Cruz-Ortega, Rocio; Meza-Figueroa, Diana; Romero, Francisco M; Sanchez-Escalante, Jose Jesus; Maier, Raina M; Neilson, Julia W; Alcaraz, Luis David; Molina Freaner, Francisco E

    2017-01-01

    Phytostabilization is a remediation technology that uses plants for in-situ stabilization of contamination in soils and mine tailings. The objective of this study was to identify native plant species with potential for phytostabilization of the abandoned mine tailings in Nacozari, Sonora in northern Mexico. A flora of 42 species in 16 families of angiosperms was recorded on the tailings site and the abundance of the most common perennial species was estimated. Four of the five abundant perennial species showed evidence of regeneration: the ability to reproduce and establish new seedlings. A comparison of selected physicochemical properties of the tailings in vegetated patches with adjacent barren areas suggests that pH, electrical conductivity, texture, and concentration of potentially toxic elements do not limit plant distribution. For the most abundant species, the accumulation factor for most metals was <1, with the exception of Zn in two species. A short-term experiment on adaptation revealed limited evidence for the formation of local ecotypes in Prosopis velutina and Amaranthus watsonii . Overall, the results of this study indicate that five native plant species might have potential for phytostabilization of the Nacozari tailings and that seed could be collected locally to revegetate the site. More broadly, this study provides a methodology that can be used to identify native plants and evaluate their phytostabilization potential for similar mine tailings.

  7. Methanogenic biodegradation of paraffinic solvent hydrocarbons in two different oil sands tailings.

    PubMed

    Mohamad Shahimin, Mohd Faidz; Siddique, Tariq

    2017-04-01

    Microbial communities drive many biogeochemical processes in oil sands tailings and cause greenhouse gas emissions from tailings ponds. Paraffinic solvent (primarily C 5 -C 6 ; n- and iso-alkanes) is used by some oil sands companies to aid bitumen extraction from oil sands ores. Residues of unrecovered solvent escape to tailings ponds during tailings deposition and sustain microbial metabolism. To investigate biodegradation of hydrocarbons in paraffinic solvent, mature fine tailings (MFT) collected from Albian and CNRL ponds were amended with paraffinic solvent at ~0.1wt% (final concentration: ~1000mgL -1 ) and incubated under methanogenic conditions for ~1600d. Albian and CNRL MFTs exhibited ~400 and ~800d lag phases, respectively after which n-alkanes (n-pentane and n-hexane) in the solvent were preferentially metabolized to methane over iso-alkanes in both MFTs. Among iso-alkanes, only 2-methylpentane was completely biodegraded whereas 2-methylbutane and 3-methylpentane were partially biodegraded probably through cometabolism. 16S rRNA gene pyrosequencing showed dominance of Anaerolineaceae and Methanosaetaceae in Albian MFT and Peptococcaceae and co-domination of "Candidatus Methanoregula" and Methanosaetaceae in CNRL MFT bacterial and archaeal communities, respectively, during active biodegradation of paraffinic solvent. The results are important for developing future strategies for tailings reclamation and management of greenhouse gas emissions. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Plants from the abandoned Nacozari mine tailings: evaluation of their phytostabilization potential

    PubMed Central

    Santos, Alina E.; Cruz-Ortega, Rocio; Meza-Figueroa, Diana; Romero, Francisco M.; Sanchez-Escalante, Jose Jesus; Maier, Raina M.; Neilson, Julia W.; Alcaraz, Luis David

    2017-01-01

    Phytostabilization is a remediation technology that uses plants for in-situ stabilization of contamination in soils and mine tailings. The objective of this study was to identify native plant species with potential for phytostabilization of the abandoned mine tailings in Nacozari, Sonora in northern Mexico. A flora of 42 species in 16 families of angiosperms was recorded on the tailings site and the abundance of the most common perennial species was estimated. Four of the five abundant perennial species showed evidence of regeneration: the ability to reproduce and establish new seedlings. A comparison of selected physicochemical properties of the tailings in vegetated patches with adjacent barren areas suggests that pH, electrical conductivity, texture, and concentration of potentially toxic elements do not limit plant distribution. For the most abundant species, the accumulation factor for most metals was <1, with the exception of Zn in two species. A short-term experiment on adaptation revealed limited evidence for the formation of local ecotypes in Prosopis velutina and Amaranthus watsonii. Overall, the results of this study indicate that five native plant species might have potential for phytostabilization of the Nacozari tailings and that seed could be collected locally to revegetate the site. More broadly, this study provides a methodology that can be used to identify native plants and evaluate their phytostabilization potential for similar mine tailings. PMID:28484675

  9. Characterization and Modeling of Dust Emissions from an Instrumented Mine Tailings Site

    NASA Astrophysics Data System (ADS)

    Betterton, E. A.; Stovern, M.; Saez, A.; Csavina, J. L.; Felix Villar, O. I.; Field, J. P.; Rine, K. P.; Russell, M. R.; Saliba, P.

    2012-12-01

    Mining operations are potential sources of airborne particulate metal and metalloid contaminants through both direct smelter emissions and wind erosion of mine tailings. The warmer, drier conditions predicted for the Southwestern US by climate models may make contaminated atmospheric dust and aerosols increasingly important, due to potential deleterious effects on human health and ecology. Dust emissions and dispersion of contaminants from the Iron King Mine tailings in Dewey-Humboldt, Arizona, a Superfund site, are currently being investigated through in situ field measurements and computational fluid dynamics modeling. These tailings are heavily contaminated with lead and arsenic. We report on the chemical characterization of atmospheric dust and aerosol sampled near the mine tailings. Instrumented eddy flux towers were also setup on the mine tailings to give both spatial and temporal dust observations. The eddy flux towers have multiple DUSTTRAK monitors as well as weather stations. These in situ observations allow us to assess spatial distribution of suspended particulate. Using the DUSTTRAK flux tower observations at 10-second resolution in conjunction with a computational fluid dynamics model, we have been able to model dust transport from the mine tailings to downwind areas. In order to improve the accuracy of the dust transport simulations both regional topographical features and local weather patterns have been incorporated into the model simulations.

  10. Tail autotomy and subsequent regeneration alter the mechanics of locomotion in lizards.

    PubMed

    Jagnandan, Kevin; Russell, Anthony P; Higham, Timothy E

    2014-11-01

    Animals can undergo significant weight change for a variety of reasons. Autotomy, the voluntary shedding of an appendage in response to a predator stimulus, provides an effective model for measuring the effects of rapid weight change on locomotor behavior and the responses to more gradual weight gain, particularly in lizards capable of both autotomizing and regenerating their tail. Although the general effects of autotomy on locomotor performance are commonly explored, we investigated changes in locomotor mechanics associated with tail loss and long-term regeneration for the first time by measuring morphology, 3D kinematics and ground reaction forces (GRFs) in the leopard gecko Eublepharis macularius. Tail autotomy resulted in a 13% anterior shift in the center of mass (CoM), which only partially recovered after full regeneration of the tail. Although no changes in body or forelimb kinematics were evident, decreases in hindlimb joint angles signify a more sprawled posture following autotomy. Changes in hindlimb GRFs resulted in an increase in weight-specific propulsive force, without a corresponding change in locomotor speed. Hindlimb kinematics and GRFs following autotomy recovered to pre-autotomy values as the tail regenerated. These results suggest an active locomotor response to tail loss that demonstrates the causal relationships between variations in morphology, kinematics and force. © 2014. Published by The Company of Biologists Ltd.

  11. Single molecule FRET observation of kinesin-1’s head-tail interaction on microtubule

    PubMed Central

    Aoki, Takahiro; Tomishige, Michio; Ariga, Takayuki

    2013-01-01

    Kinesin-1 (conventional kinesin) is a molecular motor that transports various cargo such as endoplasmic reticulum and mitochondria in cells. Its two head domains walk along microtubule by hydrolyzing ATP, while the tail domains at the end of the long stalk bind to the cargo. When a kinesin is not carrying cargo, its motility and ATPase activity is inhibited by direct interactions between the tail and head. However, the mechanism of this tail regulation is not well understood. Here, we apply single molecule fluorescence resonance energy transfer (smFRET) to observe this interaction in stalk-truncated kinesin. We found that kinesin with two tails forms a folding conformation and dissociates from microtubules, whereas kinesin with one tail remains bound to the micro-tubule and is immobile even in the presence of ATP. We further investigated the head-tail interaction as well as head-head coordination on the microtubule at various nucleotide conditions. From these results, we propose a two-step inhibition model for kinesin motility. PMID:27493553

  12. Tail-Cuff Technique and Its Influence on Central Blood Pressure in the Mouse.

    PubMed

    Wilde, Elena; Aubdool, Aisah A; Thakore, Pratish; Baldissera, Lineu; Alawi, Khadija M; Keeble, Julie; Nandi, Manasi; Brain, Susan D

    2017-06-27

    Reliable measurement of blood pressure in conscious mice is essential in cardiovascular research. Telemetry, the "gold-standard" technique, is invasive and expensive and therefore tail-cuff, a noninvasive alternative, is widely used. However, tail-cuff requires handling and restraint during measurement, which may cause stress affecting blood pressure and undermining reliability of the results. C57Bl/6J mice were implanted with radio-telemetry probes to investigate the effects of the steps of the tail-cuff technique on central blood pressure, heart rate, and temperature. This included comparison of handling techniques, operator's sex, habituation, and influence of hypertension induced by angiotensin II. Direct comparison of measurements obtained by telemetry and tail-cuff were made in the same mouse. The results revealed significant increases in central blood pressure, heart rate, and core body temperature from baseline following handling interventions without significant difference among the different handling technique, habituation, or sex of the investigator. Restraint induced the largest and sustained increase in cardiovascular parameters and temperature. The tail-cuff readings significantly underestimated those from simultaneous telemetry recordings; however, "nonsimultaneous" telemetry, obtained in undisturbed mice, were similar to tail-cuff readings obtained in undisturbed mice on the same day. This study reveals that the tail-cuff technique underestimates the core blood pressure changes that occur simultaneously during the restraint and measurement phases. However, the measurements between the 2 techniques are similar when tail-cuff readings are compared with telemetry readings in the nondisturbed mice. The differences between the simultaneous recordings by the 2 techniques should be recognized by researchers. © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

  13. Distant Tail Behavior During High Speed Solar Wind Streams and Magnetic Storms

    NASA Technical Reports Server (NTRS)

    Ho, C. M.; Tsurutani, B. T.

    1997-01-01

    We have examined the ISEE 3 distant tail data during three intense magnetic storms and have identified the tail response to high-speed solar wind streams, interplanetary magnetic clouds, and near-Earth storms.

  14. 3. VIEW OF EMPIRE STATE MINE WITH TAILING PILE IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. VIEW OF EMPIRE STATE MINE WITH TAILING PILE IN BOTTOM LEFT AND COLLAPSED ADIT LOCATED BELOW DARK SHADOWS IN FAR RIGHT/LOWER THIRD. COLLAPSED BUILDING AND PARTIAL VIEW OF ORE CHUTE/BIN IS VISIBLE ON HILLSIDE ABOVE TAILINGS. CAMERA POINTED NORTH/NORTHWEST. - Florida Mountain Mining Sites, Empire State Mine, West side of Florida Mountain, Silver City, Owyhee County, ID

  15. Chlorophyll a with a farnesyl tail in thermophilic cyanobacteria.

    PubMed

    Wiwczar, Jessica M; LaFountain, Amy M; Wang, Jimin; Frank, Harry A; Brudvig, Gary W

    2017-11-01

    Photosystem II (PSII) of oxygenic photosynthetic organisms normally contains exclusively chlorophyll a (Chl a) as its major light-harvesting pigment. Chl a canonically consists of the chlorin headgroup with a 20-carbon, 4-isoprene unit, phytyl tail. We have examined the 1.9 Å crystal structure of PSII from thermophilic cyanobacteria reported by Shen and coworkers in 2012 (PDB accession of 3ARC/3WU2). A newly refined electron density map from this structure, presented here, reveals that some assignments of the cofactors may be different from those modeled in the 3ARC/3WU2 structure, including a specific Chl a that appears to have a truncated tail by one isoprene unit. We provide experimental evidence using high-performance liquid chromatography and mass spectrometry for a small population of Chl a esterified to a 15-carbon farnesyl tail in PSII of thermophilic cyanobacteria.

  16. Empirical study of the tails of mutual fund size

    NASA Astrophysics Data System (ADS)

    Schwarzkopf, Yonathan; Farmer, J. Doyne

    2010-06-01

    The mutual fund industry manages about a quarter of the assets in the U.S. stock market and thus plays an important role in the U.S. economy. The question of how much control is concentrated in the hands of the largest players is best quantitatively discussed in terms of the tail behavior of the mutual fund size distribution. We study the distribution empirically and show that the tail is much better described by a log-normal than a power law, indicating less concentration than, for example, personal income. The results are highly statistically significant and are consistent across fifteen years. This contradicts a recent theory concerning the origin of the power law tails of the trading volume distribution. Based on the analysis in a companion paper, the log-normality is to be expected, and indicates that the distribution of mutual funds remains perpetually out of equilibrium.

  17. Experimental study of tail-span effects on a generic canard-controlled missile

    NASA Technical Reports Server (NTRS)

    Blair, A. B., Jr.; Dillon, James L.; Watson, Carolyn B.

    1992-01-01

    An experimental investigation was conducted on a cruciform canard controlled missile configuration to determine the effects of tail span/canard span ratio on controllability. The investigation was conducted over the Mach number range of 1.75 to 3.50. Reductions of tail span/canard span ratio produced lower static margins and higher trim angle of attack. The results show that canard controls can provide pitch- and yaw-control as well as roll-control by proper selection of the tail span/canard span ratio.

  18. Research on Safety Monitoring System of Tailings Dam Based on Internet of Things

    NASA Astrophysics Data System (ADS)

    Wang, Ligang; Yang, Xiaocong; He, Manchao

    2018-03-01

    The paper designed and implemented the safety monitoring system of tailings dam based on Internet of things, completed the hardware and software design of sensor nodes, routing nodes and coordinator node by using ZigBee wireless sensor chip CC2630 and 3G/4G data transmission module, developed the software platform integrated with geographic information system. The paper achieved real-time monitoring and data collection of tailings dam dam deformation, seepage line, water level and rainfall for all-weather, the stability of tailings dam based on the Internet of things monitoring is analyzed, and realized intelligent and scientific management of tailings dam under the guidance of the remote expert system.

  19. Velocity field measurements in tailings dam failure experiments using a combined PIV-PTV approach

    USDA-ARS?s Scientific Manuscript database

    Tailings dams are built to impound mining waste, also called tailings, which consists of a mixture of fine-sized sediments and water contaminated with some hazardous chemicals used for extracting the ore by leaching. Non-Newtonian flow of sediment-water mixture resulting from a failure of tailings d...

  20. Monitoring black-tailed prairie dog colonies with high-resolution satellite imagery

    USGS Publications Warehouse

    Sidle, John G.; Johnson, D.H.; Euliss, B.R.; Tooze, M.

    2002-01-01

    The United States Fish and Wildlife Service has determined that the black-tailed prairie dog (Cynomys ludovicianus) warrants listing as a threatened species under the Endangered Species Act. Central to any conservation planning for the black-tailed prairie dog is an appropriate detection and monitoring technique. Because coarse-resolution satellite imagery is not adequate to detect black-tailed prairie dog colonies, we examined the usefulness of recently available high-resolution (1-m) satellite imagery. In 6 purchased scenes of national grasslands, we were easily able to visually detect small and large colonies without using image-processing algorithms. The Ikonos (Space Imaging(tm)) satellite imagery was as adequate as large-scale aerial photography to delineate colonies. Based on the high quality of imagery, we discuss a possible monitoring program for black-tailed prairie dog colonies throughout the Great Plains, using the species' distribution in North Dakota as an example. Monitoring plots could be established and imagery acquired periodically to track the expansion and contraction of colonies.

  1. Liposomes assembled from a dual drug-tailed phospholipid for cancer therapy.

    PubMed

    Fang, Shuo; Niu, Yuge; Zhu, Wenjun; Zhang, Yemin; Yu, Liangli; Li, Xinsong

    2015-05-01

    We report a novel dual drug-tailed phospholipid which can form liposomes as a combination of prodrug and drug carrier. An amphiphilic dual chlorambucil-tailed phospholipid (DCTP) was synthesized by a straightforward esterification. With two chlorambucil molecules as hydrophobic tails and one glycerophosphatidylcholine molecule as a hydrophilic head, the DCTP, a phospholipid prodrug, undergoes assembly to form a liposome without any additives by the thin lipid film technique. The DCTP liposomes, as an effective carrier of chlorambucil, exhibited a very high loading capacity and excellent stability. The liposomes had higher cytotoxic effects to cancer cell lines than free DCTP and chlorambucil. The in vivo antitumor activity assessment indicated that the DCTP liposomes could inhibit the tumor growth effectively. This novel strategy of dual drug-tailed phospholipid liposomes may be also applicable to other hydrophobic anticancer drugs which have great potential in cancer therapy. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. An eco-friendly method for heavy metal removal from mine tailings.

    PubMed

    Arab, Fereshteh; Mulligan, Catherine N

    2018-06-01

    One of the serious environmental problems that society is facing today is mine tailings. These byproducts of the process of extraction of valuable elements from ores are a source of pollution and a threat to the environment. For example, mine tailings from past mining activities at Giant Mines, Yellowknife, are deposited in chambers, stopes, and tailing ponds close to the shores of The Great Slave Lake. One of the environmentally friendly approaches for removing heavy metals from these contaminated tailing is by using biosurfactants during the process of soil washing. The objective of this present study is to investigate the effect of sophorolipid (SL) concentration, the volume of washing solution per gram of medium, pH, and temperature on the efficiency of sophorolipids in removing heavy metals from mine tailings. It was found that the efficiency of the sophorolipids depends on its concentration, and is greatly affected by changes in pH, and temperature. The results of this experiment show that increasing the temperature from 15 to 23 °C, while using sophorolipids, resulted in an increase in the removal of iron, copper, and arsenic from the mine tailing specimen, from 0.25, 2.1, and 8.6 to 0.4, 3.3, and 11.7%. At the same time, increasing the temperature of deionized water (DIW) from 15 to 23 °C led to an increase in the removal of iron, copper, and arsenic from 0.03, 0.9, and 1.8 to 0.04, 1.1, and 2.1%, respectively. By increasing temperature from 23 to 35 °C, when using sophorolipids, 22% reduction in the removal of arsenic was observed. At the same time while using DI water as the washing solution, increasing temperature from 23 to 35 °C resulted in 6.2% increase in arsenic removal. The results from this present study indicate that sophorolipids are promising agents for replacing synthetic surfactants in the removal of arsenic and other heavy metals from soil and mine tailings.

  3. Tailings Pond Characterization And Designing Through Geophysical Surveys In Dipping Sedimentary Formations

    NASA Astrophysics Data System (ADS)

    Muralidharan, D.; Andrade, R.; Anand, K.; Sathish, R.; Goud, K.

    2009-12-01

    Mining activities results into generation of disintegrated waste materials attaining increased mobilization status and requires a safe disposal mechanism through back filling process or secluded storage on surface with prevention of its interaction with environment cycle. The surface disposal of waste materials will become more critical in case of mined minerals having toxic or radioactive elements. In such cases, the surface disposal site is to be characterized for its sub-surface nature to understand its role in environmental impact due to the loading of waste materials. Near surface geophysics plays a major role in mapping the geophysical characters of the sub-surface formations in and around the disposal site and even to certain extent helps in designing of the storage structure. Integrated geophysical methods involving resistivity tomography, ground magnetic and shallow seismic studies were carried out over proposed tailings pond area of 0.3 sq. kms underlined by dipping sedimentary rocks consisting of ferruginous shales and dolomitic to siliceous limestone with varying thicknesses. The investigated site being located in tectonically disturbed area, geophysical investigations were carried out with number of profiles to visualize the sub-surface nature with clarity. The integration of results of twenty profiles of resistivity tomography with 2 m (shallow) and 10 m (moderate depth) electrode spacing’s enabled in preparing probable sub-surface geological section along the strike direction of the formation under the tailings pond with some geo-tectonic structure inferred to be a fault. Similarly, two resistivity tomography profiles perpendicular to the strike direction of the formations brought out the existence of buried basic intrusive body on the northern boundary of the proposed tailings pond. Two resistivity tomography profiles in criss-cross direction over the suspected fault zone confirmed fault existence on the north-eastern part of tailings pond. Thirty

  4. The taxonomic status of the white-tailed kite

    USGS Publications Warehouse

    Clark, W.S.; Banks, R.C.

    1992-01-01

    The White-tailed Kite (Elanus leucurus) of the Americas has been merged with the Black-shouldered (or Black-winged) Kite (E. caeruleus) of the Old World and the Australian Black-shouldered Kite (E. axillaris) by North American authorities (but not elsewhere), primarily because of similarity in plumage. However, American kites differ from Old World kites in greater size and weight, in proportions (relatively longer tail and smaller bill and feet), plumage pattern (particularly of juveniles), and in behavior. Here we argue that these characters are sufficiently distinctive to warrant recognition of E. leucurus at the species level.

  5. Zone-tailed Hawk (Buteo albonotatus)

    Treesearch

    Scott H. Stoleson; Giancarlo Sadoti

    2010-01-01

    The Zone-tailed Hawk (Buteo albonotatus) might well be dubbed "the Great Pretender" because it so closely resembles the ubiquitous Turkey Vulture (Cathartes aura) in appearance and behavior as to be frequently mistaken for it. In the border regions where it lives, it may be confused as well with another "Mexican" raptor, the Common Black-Hawk (...

  6. Design, construction and management of tailings storage facilities for surface disposal in China: case studies of failures.

    PubMed

    Wei, Zuoan; Yin, Guangzhi; Wang, J G; Wan, Ling; Li, Guangzhi

    2013-01-01

    Rapid development of China's economy demands for more mineral resources. At the same time, a vast quantity of mine tailings, as the waste byproduct of mining and mineral processing, is being produced in huge proportions. Tailings impoundments play an important role in the practical surface disposal of these large quantities of mining waste. Historically, tailings were relatively small in quantity and had no commercial value, thus little attention was paid to their disposal. The tailings were preferably discharged near the mines and few tailings storage facilities were constructed in mainland China. This situation has significantly changed since 2000, because the Chinese economy is growing rapidly and Chinese regulations and legislation require that tailings disposal systems must be ready before the mining operation begins. Consequently, data up to 2008 shows that more than 12 000 tailings storage facilities have been built in China. This paper reviews the history of tailings disposal in China, discusses three cases of tailings dam failures and explores failure mechanisms, and the procedures commonly used in China for planning, design, construction and management of tailings impoundments. This paper also discusses the current situation, shortcomings and key weaknesses, as well as future development trends for tailings storage facilities in China.

  7. Tail position affects the body temperature of rats during cold exposure in a low-energy state.

    PubMed

    Uchida, Yuki; Tokizawa, Ken; Nakamura, Mayumi; Lin, Cheng-Hsien; Nagashima, Kei

    2012-02-01

    Rats place their tails underneath their body trunks when cold (tail-hiding behavior). The aim of the present study was to determine whether this behavior is necessary to maintain body temperature. Male Wistar rats were divided into 'fed' and '42-h fasting' groups. A one-piece tail holder (8.4 cm in length) that prevented the tail-hiding behavior or a three-piece tail holder (2.8 cm in length) that allowed for the tail-hiding behavior was attached to the tails of the rats. The rats were exposed to 27°C for 180 min or to 20°C for 90 min followed by 15°C for 90 min with continuous body temperature and oxygen consumption measurements. Body temperature decreased by -1.0 ± 0.1°C at 15°C only in the rats that prevented tail-hiding behavior of the 42-h fasting group, and oxygen consumption increased at 15°C in all animals. Oxygen consumption was not different between the rats that prevented tail-hiding behavior and the rats that allowed the behavior in the fed and 42-h fasting groups under ambient conditions. These results show that the tail-hiding behavior is involved in thermoregulation in the cold in fasting rats.

  8. Topographic home ranges of white-tailed deer in the central Appalachians

    Treesearch

    Tyler A. Campbell; Benjamin R. Laseter; W. Mark Ford; Karl V. Miller

    2004-01-01

    Planimetric comparisons of home range sizes of white-tailed deer (Odocoileus virginianus Zimmermann) from across their range may not be appropriate due to regional differences in topography. We compare seasonal topographic diversity between male and female white-tailed deer home ranges in the central Appalachians using percent increase from...

  9. Fractal and Chaos Analysis for Dynamics of Radon Exhalation from Uranium Mill Tailings

    NASA Astrophysics Data System (ADS)

    Li, Yongmei; Tan, Wanyu; Tan, Kaixuan; Liu, Zehua; Xie, Yanshi

    2016-08-01

    Tailings from mining and milling of uranium ores potentially are large volumes of low-level radioactive materials. A typical environmental problem associated with uranium tailings is radon exhalation, which can significantly pose risks to environment and human health. In order to reduce these risks, it is essential to study the dynamical nature and underlying mechanism of radon exhalation from uranium mill tailings. This motivates the conduction of this study, which is based on the fractal and chaotic methods (e.g. calculating the Hurst exponent, Lyapunov exponent and correlation dimension) and laboratory experiments of the radon exhalation rates. The experimental results show that the radon exhalation rate from uranium mill tailings is highly oscillated. In addition, the nonlinear analyses of the time series of radon exhalation rate demonstrate the following points: (1) the value of Hurst exponent much larger than 0.5 indicates non-random behavior of the radon time series; (2) the positive Lyapunov exponent and non-integer correlation dimension of the time series imply that the radon exhalation from uranium tailings is a chaotic dynamical process; (3) the required minimum number of variables should be five to describe the time evolution of radon exhalation. Therefore, it can be concluded that the internal factors, including heterogeneous distribution of radium, and randomness of radium decay, as well as the fractal characteristics of the tailings, can result in the chaotic evolution of radon exhalation from the tailings.

  10. LADEE UVS Observations of Atoms and Dust in the Lunar Tail

    NASA Technical Reports Server (NTRS)

    Wooden, Diane H.; Colaprete, Anthony; Cook, Amanda M.; Shirley, Mark H.; Vargo, Kara E.; Elphic, Richard C.; Stubbs, Timothy J.; Glenar, David A.

    2014-01-01

    The Lunar Atmosphere and Dust Environment Explorer (LADEE) was a lunar orbiter launched in September 2013 that investigated the composition and temporal variation of the tenuous lunar exosphere and dust environment. A major goal of the mission was to characterize the dust exosphere prior to future lunar exploration activities, which may alter the lunar environment. The Ultraviolet/Visible Spectrometer (UVS) onboard LADEE addresses this goal, utilizing two sets of optics: a limbviewing telescope, and a solar-viewing telescope. We report on spectroscopic (approximately 280 - 820 nm) observations viewing down the lunar wake or along the 'lunar tail' from lunar orbit. Prior groundbased studies have observed the emission from neutral sodium atoms extended along the lunar tail, so often this region is referred to as the lunar sodium tail. UVS measurements were made on the dark side of the moon, with the UVS limb-viewing telescope pointed outward in the direction of the Moon's wake (almost anti-sun), during different lunar phases. These UVS observation activities sample a long column and allow the characterization of scattered light from dust and emission lines from atoms in the lunar tail. Observations in this UVS configuration show the largest excess of scattered blue light in our data set, indicative of the presence of small dust grains in the tail. Once lofted, nanoparticles may become charged and picked up by the solar wind, similar to the phenomena witnessed above Enceladus's northern hemisphere or by the STEREO/WAVES instrument while close to Earth's orbit. The UVS data show that small dust grains as well as atoms become entrained in the lunar tail.

  11. Mean Excess Function as a method of identifying sub-exponential tails: Application to extreme daily rainfall

    NASA Astrophysics Data System (ADS)

    Nerantzaki, Sofia; Papalexiou, Simon Michael

    2017-04-01

    Identifying precisely the distribution tail of a geophysical variable is tough, or, even impossible. First, the tail is the part of the distribution for which we have the less empirical information available; second, a universally accepted definition of tail does not and cannot exist; and third, a tail may change over time due to long-term changes. Unfortunately, the tail is the most important part of the distribution as it dictates the estimates of exceedance probabilities or return periods. Fortunately, based on their tail behavior, probability distributions can be generally categorized into two major families, i.e., sub-exponentials (heavy-tailed) and hyper-exponentials (light-tailed). This study aims to update the Mean Excess Function (MEF), providing a useful tool in order to asses which type of tail better describes empirical data. The MEF is based on the mean value of a variable over a threshold and results in a zero slope regression line when applied for the Exponential distribution. Here, we construct slope confidence intervals for the Exponential distribution as functions of sample size. The validation of the method using Monte Carlo techniques on four theoretical distributions covering major tail cases (Pareto type II, Log-normal, Weibull and Gamma) revealed that it performs well especially for large samples. Finally, the method is used to investigate the behavior of daily rainfall extremes; thousands of rainfall records were examined, from all over the world and with sample size over 100 years, revealing that heavy-tailed distributions can describe more accurately rainfall extremes.

  12. Scar-free wound healing and regeneration following tail loss in the leopard gecko, Eublepharis macularius.

    PubMed

    Delorme, Stephanie Lynn; Lungu, Ilinca Mihaela; Vickaryous, Matthew Kenneth

    2012-10-01

    Many lizards are able to undergo scar-free wound healing and regeneration following loss of the tail. In most instances, lizard tail loss is facilitated by autotomy, an evolved mechanism that permits the tail to be self-detached at pre-existing fracture planes. However, it has also been reported that the tail can regenerate following surgical amputation outside the fracture plane. In this study, we used the leopard gecko, Eublepharis macularius, to investigate and compare wound healing and regeneration following autotomy at a fracture plane and amputation outside the fracture plane. Both forms of tail loss undergo a nearly identical sequence of events leading to scar-free wound healing and regeneration. Early wound healing is characterized by transient myofibroblasts and the formation of a highly proliferative wound epithelium immunoreactive for the wound keratin marker WE6. The new tail forms from what is commonly referred to as a blastema, a mass of proliferating mesenchymal-like cells. Blastema cells express the protease matrix metalloproteinase-9. Apoptosis (demonstrated by activated caspase 3 immunostaining) is largely restricted to isolated cells of the original and regenerating tail tissues, although cell death also occurs within dermal structures at the original-regenerated tissue interface and among clusters of newly formed myocytes. Furthermore, the autotomized tail is unique in demonstrating apoptosis among cells adjacent to the fracture planes. Unlike mammals, transforming growth factor-β3 is not involved in wound healing. We demonstrate that scar-free wound healing and regeneration are intrinsic properties of the tail, unrelated to the location or mode of tail detachment. Copyright © 2012 Wiley Periodicals, Inc.

  13. On the Polarization Properties of Magnetar Giant Flare Pulsating Tails

    NASA Astrophysics Data System (ADS)

    Yang, Yuan-Pei; Zhang, Bing

    2015-12-01

    Three giant flares have been detected so far from soft gamma-ray repeaters, each characterized by an initial short hard spike and a pulsating tail. The observed pulsating tails are characterized by a duration of ˜100 s, an isotropic energy of ˜1044 erg, and a pulse period of a few seconds. The pulsating tail emission likely originates from the residual energy after the intense energy release during the initial spike, which forms a trapped fireball composed of a photon-pair plasma in a closed-field-line region of the magnetars. Observationally the spectra of pulsating tails can be fitted by the superposition of a thermal component and a power-law component, with the thermal component dominating the emission in the early and late stages of the pulsating-tail observations. In this paper, assuming that the trapped fireball is from a closed-field-line region in the magnetosphere, we calculate the atmospheric structure of the optically thick trapped fireball and the polarization properties of the trapped fireball. By properly treating the photon propagation in a hot, highly magnetized, electron-positron pair plasma, we tally photons in two modes (O mode and E mode) at a certain observational angle through Monte Carlo simulations. Our results suggest that the polarization degree depends on the viewing angle with respect to the magnetic axis of the magnetar, and can be as high as Π ≃ 30% in the 1-30 keV band, and Π ≃ 10% in the 30-100 keV band, if the line of sight is perpendicular to the magnetic axis.

  14. Behavioural responses of dogs to asymmetrical tail wagging of a robotic dog replica.

    PubMed

    Artelle, K A; Dumoulin, L K; Reimchen, T E

    2011-03-01

    Recent evidence suggests that bilateral asymmetry in the amplitude of tail wagging of domestic dogs (Canis familiaris) is associated with approach (right wag) versus withdrawal (left wag) motivation and may be the by-product of hemispheric dominance. We consider whether such asymmetry in motion of the tail, a crucial appendage in intra-specific communication in all canids, provides visual information to a conspecific leading to differential behaviour. To evaluate this, we experimentally investigated the approach behaviour of free-ranging dogs to the asymmetric tail wagging of a life-size robotic dog replica. Our data, involving 452 separate interactions, showed a significantly greater proportion of dogs approaching the model continuously without stopping when the tail wagged to the left, compared with a right wag, which was more likely to yield stops. While the results indicate that laterality of a wagging tail provides behavioural information to conspecifics, the responses are not readily integrated into the predicted behaviour based on hemispheric dominance.

  15. Phylogenetic and pathogenic characterization of novel adenoviruses from long-tailed ducks (Clangula hyemalis)

    USGS Publications Warehouse

    Counihan, Katrina; Skerratt, Lee; Franson, J. Christian; Hollmen, Tuula E.

    2015-01-01

    Novel adenoviruses were isolated from a long-tailed duck (Clangula hyemalis) mortality event near Prudhoe Bay, Alaska in 2000. The long-tailed duck adenovirus genome was approximately 27 kb. A 907 bp hexon gene segment was used to design primers specific for the long-tailed duck adenovirus. Nineteen isolates were phylogenetically characterized based on portions of their hexon gene and 12 were most closely related to Goose adenovirus A. The remaining 7 shared no hexon sequences with any known adenoviruses. Experimental infections of mallards with a long-tailed duck reference adenovirus caused mild lymphoid infiltration of the intestine and paint brush hemorrhages of the mucosa and dilation of the intestine. This study shows novel adenoviruses from long-tailed ducks are diverse and provides further evidence that they should be considered in cases of morbidity and mortality in sea ducks. Conserved and specific primers have been developed that will help screen sea ducks for adenoviral infections.

  16. Role of mycorrhizal colonization in plant establishment on an alkaline gold mine tailing.

    PubMed

    Orłowska, Elzbieta; Orłowski, Dariusz; Mesjasz-Przybyłowicz, Jolanta; Turnau, Katarzyna

    2011-02-01

    The potential role of arbuscular mycorrhizal fungi (AMF) in the revegetation of an alkaline gold mine tailing was studied in Barberton, South Africa. The tailing, characterized by a slow spontaneous plant succession, is colonized by the shrub Dodonaea viscosa and the grasses, Andropogon eucomus and Imperata cylindrica, all colonized by AMF. The effectiveness of mycorrhizal colonization in grasses was tested under laboratory conditions using fungal isolates of various origins. Both grasses were highly mycorrhiza dependent, and the presence of mycorrhizal colonization significantly increased their biomass and survival rates. The fungi originating from the gold tailing were better adapted to the special conditions of the tailing than the control isolate. Although the total colonization rate found for native fungi was lower than for fungi from non-polluted sites, they were more vital and more effective in promoting plant growth. The results obtained might serve as a practical approach to the phytostabilization of alkaline gold tailings.

  17. Seeing left- or right-asymmetric tail wagging produces different emotional responses in dogs.

    PubMed

    Siniscalchi, Marcello; Lusito, Rita; Vallortigara, Giorgio; Quaranta, Angelo

    2013-11-18

    Left-right asymmetries in behavior associated with asymmetries in the brain are widespread in the animal kingdom, and the hypothesis has been put forward that they may be linked to animals' social behavior. Dogs show asymmetric tail-wagging responses to different emotive stimuli-the outcome of different activation of left and right brain structures controlling tail movements to the right and left side of the body. A crucial question, however, is whether or not dogs detect this asymmetry. Here we report that dogs looking at moving video images of conspecifics exhibiting prevalent left- or right-asymmetric tail wagging showed higher cardiac activity and higher scores of anxious behavior when observing left- rather than right-biased tail wagging. The finding that dogs are sensitive to the asymmetric tail expressions of other dogs supports the hypothesis of a link between brain asymmetry and social behavior and may prove useful to canine animal welfare theory and practice. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. Liposome-like nanocapsules of dual drug-tailed betaine for cancer therapy.

    PubMed

    Fang, Shuo; Niu, Yuge; Zhang, Wei; Zhang, Yemin; Yu, Liangli; Zhang, Yingyi; Li, Xinsong

    2015-09-30

    A novel dual drug-tailed betaine conjugate amphiphile has been firstly synthesized in which the polar headgroup is derived from glycine betaine and the hydrophobic tails are chlorambucil molecules. The newly prepared conjugate undergoes self-assembly to form stable liposome-like nanocapsules as an effective carrier with high drug loading capacity. The nanocapsules showed higher cytotoxic effects to cancer cell lines than those of free chlorambucil in vitro, and inhibited tumor growth effectively in vivo. This strategy that utilizes new dual drug-tailed betaine conjugate amphiphile to construct a self-assembled nanoparticle drug delivery system may have great potential in cancer chemotherapy. Copyright © 2015 Elsevier B.V. All rights reserved.

  19. An Investigation at Low Speed of the Spin Instability of Mortar-Shell Tails

    NASA Technical Reports Server (NTRS)

    Bird, John D.; Lichtenstein, Jacob H.

    1957-01-01

    An investigation was made in the Langley stability tunnel to study the influence of number of fins, fin shrouding, and fin aspect ratio on the spin instability of mortar-shell tail surfaces. It was found that the 12-fin tails tested spun less rapidly throughout the angle-of-yaw range than did the 6-fin tails and that fin shrouding reduced the spin encountered by a large amount.

  20. Dwarf Galaxies Swimming in Tidal Tails

    NASA Technical Reports Server (NTRS)

    2005-01-01

    This false-color infrared image from NASA's Spitzer Space Telescope shows little 'dwarf galaxies' forming in the 'tails' of two larger galaxies that are colliding together. The big galaxies are at the center of the picture, while the dwarfs can be seen as red dots in the red streamers, or tidal tails. The two blue dots above the big galaxies are stars in the foreground.

    Galaxy mergers are common occurrences in the universe; for example, our own Milky Way galaxy will eventually smash into the nearby Andromeda galaxy. When two galaxies meet, they tend to rip each other apart, leaving a trail, called a tidal tail, of gas and dust in their wake. It is out of this galactic debris that new dwarf galaxies are born.

    The new Spitzer picture demonstrates that these particular dwarfs are actively forming stars. The red color indicates the presence of dust produced in star-forming regions, including organic molecules called polycyclic aromatic hydrocarbons. These carbon-containing molecules are also found on Earth, in car exhaust and on burnt toast, among other places. Here, the molecules are being heated up by the young stars, and, as a result, shine in infrared light.

    This image was taken by the infrared array camera on Spitzer. It is a 4-color composite of infrared light, showing emissions from wavelengths of 3.6 microns (blue), 4.5 microns (green), 5.8 microns (orange), and 8.0 microns (red). Starlight has been subtracted from the orange and red channels in order to enhance the dust features.

  1. A passerine spreads its tail to facilitate a rapid recovery of its body posture during hovering

    PubMed Central

    Su, Jian-Yuan; Ting, Shang-Chieh; Chang, Yu-Hung; Yang, Jing-Tang

    2012-01-01

    We demonstrate experimentally that a passerine exploits tail spreading to intercept the downward flow induced by its wings to facilitate the recovery of its posture. The periodic spreading of its tail by the White-eye bird exhibits a phase correlation with both wingstroke motion and body oscillation during hovering flight. During a downstroke, a White-eye's body undergoes a remarkable pitch-down motion, with the tail undergoing an upward swing. This pitch-down motion becomes appropriately suppressed at the end of the downstroke; the bird's body posture then recovers gradually to its original status. Employing digital particle-image velocimetry, we show that the strong downward flow induced by downstroking the wings serves as an external jet flow impinging upon the tail, providing a depressing force on the tail to counteract the pitch-down motion of the bird's body. Spreading of the tail enhances a rapid recovery of the body posture because increased forces are experienced. The maximum force experienced by a spread tail is approximately 2.6 times that of a non-spread tail. PMID:22258552

  2. A passerine spreads its tail to facilitate a rapid recovery of its body posture during hovering.

    PubMed

    Su, Jian-Yuan; Ting, Shang-Chieh; Chang, Yu-Hung; Yang, Jing-Tang

    2012-07-07

    We demonstrate experimentally that a passerine exploits tail spreading to intercept the downward flow induced by its wings to facilitate the recovery of its posture. The periodic spreading of its tail by the White-eye bird exhibits a phase correlation with both wingstroke motion and body oscillation during hovering flight. During a downstroke, a White-eye's body undergoes a remarkable pitch-down motion, with the tail undergoing an upward swing. This pitch-down motion becomes appropriately suppressed at the end of the downstroke; the bird's body posture then recovers gradually to its original status. Employing digital particle-image velocimetry, we show that the strong downward flow induced by downstroking the wings serves as an external jet flow impinging upon the tail, providing a depressing force on the tail to counteract the pitch-down motion of the bird's body. Spreading of the tail enhances a rapid recovery of the body posture because increased forces are experienced. The maximum force experienced by a spread tail is approximately 2.6 times that of a non-spread tail.

  3. Langmuir monolayers composed of single and double tail sulfobetaine lipids.

    PubMed

    Hazell, Gavin; Gee, Anthony P; Arnold, Thomas; Edler, Karen J; Lewis, Simon E

    2016-07-15

    Owing to structural similarities between sulfobetaine lipids and phospholipids it should be possible to form stable Langmuir monolayers from long tail sulfobetaines. By modification of the density of lipid tail group (number of carbon chains) it should also be possible to modulate the two-dimensional phase behaviour of these lipids and thereby compare with that of equivalent phospholipids. Potentially this could enable the use of such lipids for the wide array of applications that currently use phospholipids. The benefit of using sulfobetaine lipids is that they can be synthesised by a one-step reaction from cheap and readily available starting materials and will degrade via different pathways than natural lipids. The molecular architecture of the lipid can be easily modified allowing the design of lipids for specific purposes. In addition the reversal of the charge within the sulfobetaine head group relative to the charge orientation in phospholipids may modify behaviour and thereby allow for novel uses of these surfactants. Stable Langmuir monolayers were formed composed of single and double tailed sulfobetaine lipids. Surface pressure-area isotherm, Brewster Angle Microscopy and X-ray and neutron reflectometry measurements were conducted to measure the two-dimensional phase behaviour and out-of-plane structure of the monolayers as a function of molecular area. Sulfobetaine lipids are able to form stable Langmuir monolayers with two dimensional phase behaviour analogous to that seen for the well-studied phospholipids. Changing the number of carbon tail groups on the lipid from one to two promotes the existence of a liquid condensed phase due to increased Van der Waals interactions between the tail groups. Thus the structure of the monolayers appears to be defined by the relative sizes of the head and tail groups in a predictable way. However, the presence of sub-phase ions has little effect on the monolayer structure, behaviour that is surprisingly different to

  4. A protocol to correct for intra- and interspecific variation in tail hair growth to align isotope signatures of segmentally cut tail hair to a common time line.

    PubMed

    Burnik Šturm, Martina; Pukazhenthi, Budhan; Reed, Dolores; Ganbaatar, Oyunsaikhan; Sušnik, Stane; Haymerle, Agnes; Voigt, Christian C; Kaczensky, Petra

    2015-06-15

    In recent years, segmental stable isotope analysis of hair has been a focus of research in animal dietary ecology and migration. To correctly assign tail hair segments to seasons or even Julian dates, information on tail hair growth rates is a key parameter, but is lacking for most species. We (a) reviewed the literature on tail hair growth rates in mammals; b) made own measurements of three captive equid species; (c) measured δ(2)H, δ(13)C and δ(15)N values in sequentially cut tail hairs of three sympatric, free-ranging equids from the Mongolian Gobi, using isotope ratio mass spectrometry (IRMS); and (d) collected environmental background data on seasonal variation by measuring δ(2)H values in precipitation by IRMS and by compiling pasture productivity measured by remote sensing via the normalized difference vegetation index (NDVI). Tail hair growth rates showed significant inter- and intra-specific variation making temporal alignment problematic. In the Mongolian Gobi, high seasonal variation of δ(2)H values in precipitation results in winter lows and summer highs of δ(2)H values of available water sources. In water-dependent equids, this seasonality is reflected in the isotope signatures of sequentially cut tails hairs. In regions which are subject to strong seasonal patterns we suggest identifying key isotopes which show strong seasonal variation in the environment and can be expected to be reflected in the animal tissue. The known interval between the maxima and minima of these isotope values can then be used to correctly temporally align the segmental stable isotope signature for each individual animal. © 2015 The Authors. Rapid Communications in Mass Spectrometry published by John Wiley & Sons Ltd.

  5. The impact of tail tip amputation and ink tattoo on C57BL/6JBomTac mice.

    PubMed

    Sørensen, Dorte Bratbo; Stub, Charlotte; Jensen, Henrik Elvang; Ritskes-Hoitinga, Merel; Hjorth, Peter; Ottesen, Jan Lund; Hansen, Axel Kornerup

    2007-01-01

    Genetic material for polymerase chain reaction (PCR) and Southern blot analysis on transgenic mice is normally obtained by tail biopsy. Additionally, it may be necessary to tattoo the mice, as it is essential to have a good and permanent identification. The aim of this study was to evaluate the effects of amputating the tip of the tail to obtain a biopsy for genetic analysis and of ink tattooing on welfare in C57BL/6J mice, a strain often used as genetic background for transgenes. The behaviour of the animals, fluctuating asymmetry (FA, a measure of developmental instability) and the level of restitution in the remaining part of the tail were evaluated and used for an assessment of the impact of these procedures on the welfare of the animals. One group of mice was marked by tail tattooing at various ages. Another group of mice were tail amputated at 12 or 20 days of age. Body weight and FA were followed, and at the end of the experiment, the level of fear/anxiety was assessed using a light-dark box. In the group of tail-amputated animals observation of climbing behaviour and a beam walking test for balance was performed. Seven weeks after tail amputation, the animals were euthanized. The remaining part of the tail was evaluated histopathologically. Body weight, behaviour in the light-dark box and balance test results were not influenced by tail amputation or tattooing. FA was only transiently increased by tattooing. Climbing behaviour was reduced just after tail amputation at 20 days of age. No signs of neuromas were found in the amputated tails, but seven weeks after amputation a significant number of mice did not have fully regenerated glandular tissue and hair follicles in the tail. It is concluded that both tail amputation and tail tattooing seem to have minor short-term negative effects on welfare and that the tissues on the tail probably do not regenerate fully after amputation.

  6. Subsonic Aerodynamic Characteristics of an Airplane Configuration with a 63 deg Sweptback Wing and Twin-Boom Tails

    NASA Technical Reports Server (NTRS)

    Savage, Howard F.; Edwards, George G.

    1959-01-01

    A wind-tunnel investigation has been conducted to determine the effects of an unconventional tail arrangement on the subsonic static longitudinal and lateral stability characteristics of a model having a 63 deg sweptback wing of aspect ratio 3.5 and a fuselage. Tail booms, extending rearward from approximately the midsemispan of each wing panel, supported independent tail assemblies well outboard of the usual position at the rear of the fuselage. The horizontal-tail surfaces had the leading edge swept back 45 deg and an aspect ratio of 2.4. The vertical tail surfaces were geometrically similar to one panel of the horizontal tail. For comparative purposes, the wing-body combination was also tested with conventional fuselage-mounted tail surfaces. The wind-tunnel tests were conducted at Mach numbers from 0.25 to 0.95 with a Reynolds number of 2,000,000, at a Mach number of 0.46 with a Reynolds number of 3,500,000, and at a Mach number of 0.20 with a Reynolds number of 7,000,000. The results of the investigation indicate that longitudinal stability existed to considerably higher lift coefficients for the outboard tail configuration than for the configuration with conventional tail. Wing fences were necessary with both configurations for the elimination of sudden changes in longitudinal stability at lift coefficients between 0.3 and 0.5. Sideslip angles up to 15 deg had only small effects upon the pitching-moment characteristics of the outboard tail configuration. There was an increase in the directional stability for the outboard tail configuration at the higher angles of attack as opposed to a decrease for the conventional tail configuration at most of the Mach numbers and Reynolds numbers of this investigation. The dihedral effect increased rapidly with increasing angle of attack for both the outboard and the conventional tail configurations but the increase was greater for the outboard tail configuration. The data indicate that the outboard tail is an effective

  7. Relaxed open mouth as a playful signal in wild ring-tailed lemurs.

    PubMed

    Palagi, Elisabetta; Norscia, Ivan; Spada, Giulia

    2014-11-01

    Play signals are commonly used by animals to communicate their playful motivation and to limit the risk that rough acts are misunderstood by playmates. The relaxed open mouth is the most common facial expression performed during play in many mammals and represents the ritualized version of the movement anticipating a play bite. The signaling nature of this expression has been proven in many haplorrhine species but never demonstrated in strepsirrhines. Our purpose was assessing whether, also in strepsirrhines, the relaxed open mouth has an actual communicative function. We studied wild ring-tailed lemurs (Lemur catta), characterized by highly social habits including intense playful interactions. They largely use playful signals, mostly performed with the black and white tail. The signaling function of the tail (tail play) has been widely demonstrated. We analyzed both tail play and the relaxed open mouth to verify how their distribution is affected by different play variables (e.g., play session symmetry, number of play mates, previous use of the same pattern). Indeed, ring-tailed lemurs use the relaxed open mouth as a communicative signal during play. Relaxed open mouth was more frequent during unbalanced interactions showing the highest asymmetry in the patterns performed by the two players (offensive/neutral). Compared to tail play, relaxed open mouth was more frequent during dyadic than polyadic interactions and, as a highly directional signal, it was more frequently replicated by the play mate. Therefore, the relaxed open mouth needs to be performed face-to-face so that signal detection can be optimized. Similar to previous findings in monkeys and apes, the relaxed open mouth in lemurs seems to be a ritualized signal used to engage and, perhaps, sustain playful interaction. © 2014 Wiley Periodicals, Inc.

  8. Microbially-accelerated consolidation of oil sands tailings. Pathway II: solid phase biogeochemistry.

    PubMed

    Siddique, Tariq; Kuznetsov, Petr; Kuznetsova, Alsu; Li, Carmen; Young, Rozlyn; Arocena, Joselito M; Foght, Julia M

    2014-01-01

    Consolidation of clay particles in aqueous tailings suspensions is a major obstacle to effective management of oil sands tailings ponds in northern Alberta, Canada. We have observed that microorganisms indigenous to the tailings ponds accelerate consolidation of mature fine tailings (MFT) during active metabolism by using two biogeochemical pathways. In Pathway I, microbes alter porewater chemistry to indirectly increase consolidation of MFT. Here, we describe Pathway II comprising significant, direct and complementary biogeochemical reactions with MFT mineral surfaces. An anaerobic microbial community comprising Bacteria (predominantly Clostridiales, Synergistaceae, and Desulfobulbaceae) and Archaea (Methanolinea/Methanoregula and Methanosaeta) transformed Fe(III) minerals in MFT to amorphous Fe(II) minerals during methanogenic metabolism of an added organic substrate. Synchrotron analyses suggested that ferrihydrite (5Fe2O3. 9H2O) and goethite (α-FeOOH) were the dominant Fe(III) minerals in MFT. The formation of amorphous iron sulfide (FeS) and possibly green rust entrapped and masked electronegative clay surfaces in amended MFT. Both Pathways I and II reduced the surface charge potential (repulsive forces) of the clay particles in MFT, which aided aggregation of clays and formation of networks of pores, as visualized using cryo-scanning electron microscopy (SEM). These reactions facilitated the egress of porewater from MFT and increased consolidation of tailings solids. These results have large-scale implications for management and reclamation of oil sands tailings ponds, a burgeoning environmental issue for the public and government regulators.

  9. Microbially-accelerated consolidation of oil sands tailings. Pathway II: solid phase biogeochemistry

    PubMed Central

    Siddique, Tariq; Kuznetsov, Petr; Kuznetsova, Alsu; Li, Carmen; Young, Rozlyn; Arocena, Joselito M.; Foght, Julia M.

    2014-01-01

    Consolidation of clay particles in aqueous tailings suspensions is a major obstacle to effective management of oil sands tailings ponds in northern Alberta, Canada. We have observed that microorganisms indigenous to the tailings ponds accelerate consolidation of mature fine tailings (MFT) during active metabolism by using two biogeochemical pathways. In Pathway I, microbes alter porewater chemistry to indirectly increase consolidation of MFT. Here, we describe Pathway II comprising significant, direct and complementary biogeochemical reactions with MFT mineral surfaces. An anaerobic microbial community comprising Bacteria (predominantly Clostridiales, Synergistaceae, and Desulfobulbaceae) and Archaea (Methanolinea/Methanoregula and Methanosaeta) transformed FeIII minerals in MFT to amorphous FeII minerals during methanogenic metabolism of an added organic substrate. Synchrotron analyses suggested that ferrihydrite (5Fe2O3. 9H2O) and goethite (α-FeOOH) were the dominant FeIII minerals in MFT. The formation of amorphous iron sulfide (FeS) and possibly green rust entrapped and masked electronegative clay surfaces in amended MFT. Both Pathways I and II reduced the surface charge potential (repulsive forces) of the clay particles in MFT, which aided aggregation of clays and formation of networks of pores, as visualized using cryo-scanning electron microscopy (SEM). These reactions facilitated the egress of porewater from MFT and increased consolidation of tailings solids. These results have large-scale implications for management and reclamation of oil sands tailings ponds, a burgeoning environmental issue for the public and government regulators. PMID:24711806

  10. Time-varying motor control of autotomized leopard gecko tails: multiple inputs and behavioral modulation.

    PubMed

    Higham, Timothy E; Russell, Anthony P

    2012-02-01

    Autotomy (voluntary loss of an appendage) is common among diverse groups of vertebrates and invertebrates, and much attention has been given to ecological and developmental aspects of tail autotomy in lizards. Although most studies have focused on the ramifications for the lizard (behavior, biomechanics, energetics, etc.), the tail itself can exhibit interesting behaviors once segregated from the body. For example, recent work highlighted the ability of leopard gecko tails to jump and flip, in addition to being able to swing back and forth. Little is known, however, about the control mechanisms underlying these movements. Using electromyography, we examined the time-varying in vivo motor patterns at four sites (two proximal and two distal) in the tail of the leopard gecko, Eublepharis macularius, following autotomy. Using these data we tested the hypothesis that the disparity in movements results simply from overlapping pattern generators within the tail. We found that burst duration, but not cycle duration, of the rhythmic swings reached a plateau at approximately 150 s following autotomy. This is likely because of physiological changes related to muscle fatigue and ischemia. For flips and jumps, burst and cycle duration exhibited no regular pattern. The coefficient of variation in motor patterns was significantly greater for jumps and flips than for rhythmic swings. This supports the conclusion that the different tail behaviors do not stem from overlapping pattern generators, but that they rely upon independent neural circuits. The signal controlling jumps and flips may be modified by sensory information from the environment. Finally, we found that jumps and flips are initiated using relatively synchronous activity between the two sides of the tail. In contrast, alternating activation of the right and left sides of the tail result in rhythmic swings. The mechanism underlying this change in tail behavior is comparable to locomotor gait changes in vertebrates.

  11. Predicting the long tail of book sales: Unearthing the power-law exponent

    NASA Astrophysics Data System (ADS)

    Fenner, Trevor; Levene, Mark; Loizou, George

    2010-06-01

    The concept of the long tail has recently been used to explain the phenomenon in e-commerce where the total volume of sales of the items in the tail is comparable to that of the most popular items. In the case of online book sales, the proportion of tail sales has been estimated using regression techniques on the assumption that the data obeys a power-law distribution. Here we propose a different technique for estimation based on a generative model of book sales that results in an asymptotic power-law distribution of sales, but which does not suffer from the problems related to power-law regression techniques. We show that the proportion of tail sales predicted is very sensitive to the estimated power-law exponent. In particular, if we assume that the power-law exponent of the cumulative distribution is closer to 1.1 rather than to 1.2 (estimates published in 2003, calculated using regression by two groups of researchers), then our computations suggest that the tail sales of Amazon.com, rather than being 40% as estimated by Brynjolfsson, Hu and Smith in 2003, are actually closer to 20%, the proportion estimated by its CEO.

  12. Ionic Liquids with Symmetric Diether Tails: Bulk and Vacuum-Liquid Interfacial Structures.

    PubMed

    Hettige, Jeevapani J; Amith, Weththasinghage D; Castner, Edward W; Margulis, Claudio J

    2017-01-12

    The behavior in the bulk and at interfaces of biphilic ionic liquids in which either the cation or anion possesses moderately long alkyl tails is to a significant degree well understood. Less clear is what happens when both the cation and anion possess tails that are not apolar, such as in the case of ether functionalities. The current article discusses the structural characteristics of C2OC2OC2-mim + /C2OC2OC2-OSO 3 - in the bulk and at the vacuum interface. We find that the vacuum interface affects only the nanometer length scale. This is in contrast to what we have recently found in ( J. Phys. Chem. Lett. , 2016 , 7 ( 19 ), 3785 - -3790 ) for isoelectronic C[8]-mim + /C[8]-OSO 3 - , where the interface effect is long ranged. Interestingly, ions with the diether tail functionality still favor the tail-outward orientation at the vacuum interface and the bulk phase preserves the alternation between charged networks and tails that is commonly observed for biphilic ionic liquids. However, such alternation is less well-defined and results in a significantly diminished first sharp diffraction peak in the bulk liquid structure function.

  13. Implications of long tails in the distribution of mutant effects

    NASA Astrophysics Data System (ADS)

    Waxman, D.; Feng, J.

    2005-07-01

    Long-tailed distributions possess an infinite variance, yet a finite sample that is drawn from such a distribution has a finite variance. In this work we consider a model of a population subject to mutation, selection and drift. We investigate the implications of a long-tailed distribution of mutant allelic effects on the distribution of genotypic effects in a model with a continuum of allelic effects. While the analysis is confined to asexual populations, it does also have implications for sexual populations. We obtain analytical results for a selectively neutral population as well as one subject to selection. We supplement these analytical results with numerical simulations, to take into account genetic drift. We find that a long-tailed distribution of mutant effects may affect both the equilibrium and the evolutionary adaptive behaviour of a population.

  14. A True Human Tail in a Neonate: Case report and literature review.

    PubMed

    Pillai, Mahesh K; Nair, Smitha T

    2017-02-01

    A true human tail is a benign vestigial caudal cutaneous structure composed of adipose, connective tissue, muscle, vessels, nerves and mechanoreceptors. A true human tail can be distinguished from a pseudotail as the latter is commonly associated with underlying spinal dysraphism, which requires specialised management. True human tails are very rare, with fewer than 40 cases reported to date. We report a healthy one-day-old male newborn who was referred to the Bharath Hospital, Kottayam, Kerala, India, in 2014 with a cutaneous appendage arising from the lumbosacral region. Magnetic resonance imaging of the spine ruled out spinal dysraphism. The appendage was removed by simple surgical excision. Clinicians should emphasise use of 'true tail' and 'pseudotail' as specific disparate terms as the clinical, radiological and histological findings of these conditions differ significantly, along with management strategies and outcomes.

  15. Feasibility Studies on Pipeline Disposal of Concentrated Copper Tailings Slurry for Waste Minimization

    NASA Astrophysics Data System (ADS)

    Senapati, Pradipta Kumar; Mishra, Barada Kanta

    2017-06-01

    The conventional lean phase copper tailings slurry disposal systems create pollution all around the disposal area through seepage and flooding of waste slurry water. In order to reduce water consumption and minimize pollution, the pipeline disposal of these waste slurries at high solids concentrations may be considered as a viable option. The paper presents the rheological and pipeline flow characteristics of copper tailings samples in the solids concentration range of 65-72 % by weight. The tailings slurry indicated non-Newtonian behaviour at these solids concentrations and the rheological data were best fitted by Bingham plastic model. The influence of solids concentration on yield stress and plastic viscosity for the copper tailings samples were discussed. Using a high concentration test loop, pipeline experiments were conducted in a 50 mm nominal bore (NB) pipe by varying the pipe flow velocity from 1.5 to 3.5 m/s. A non-Newtonian Bingham plastic pressure drop model predicted the experimental data reasonably well for the concentrated tailings slurry. The pressure drop model was used for higher size pipes and the operating conditions for pipeline disposal of concentrated copper tailings slurry in a 200 mm NB pipe with respect to specific power consumption were discussed.

  16. Modelling hydrological processes and dissolved organic carbon dynamics in a rehabilitated Sphagnum-dominated peatland

    NASA Astrophysics Data System (ADS)

    Bernard-Jannin, Léonard; Binet, Stéphane; Gogo, Sébastien; Leroy, Fabien; Perdereau, Laurent; Laggoun-Défarge, Fatima

    2017-04-01

    Sphagnum-dominated peatlands represent a global major stock of carbon (C). Dissolved organic carbon (DOC) exports through runoff and leaching could reduce their potential C sink function and impact downstream water quality. DOC production in peatlands is strongly controlled by the hydrology, especially water table depth (WTD). Therefore, disturbances such as drainage can lead to increase DOC exports by lowering the WTD. Hydrological restoration (e.g. rewetting) can be undertaken to restore peatland functioning with an impact on DOC exports. The objective of this study is to assess the impact of drainage and rewetting on hydrological processes and their interactions with DOC dynamics in a Sphagnum dominated peatland. A hydrological model has been applied to a drained peatland (La Guette, France) which experienced a rewetting action on February 2014 and where WTD has been recorded in four piezometers at a 15 min time step since 2009. In addition, DOC concentrations in the peatland have been measured 6 times a year since 2014. The hydrological model is a WTD dependent reservoir model composed by two reservoirs representing the micro and macro porosity of the peatland (Binet et al., 2013). A DOC production module in both reservoirs was implemented based on temperature and WTD. The model was calibrated against WTD and DOC concentrations for each piezometer. The results show that the WTD in the study area is strongly affected by local meteorological conditions that could hide the effect of the rewetting action. The preliminary results evidenced that an additional source of water, identified as groundwater supply originating from the surrounding sandy layer aquifer, is necessary to maintain the water balance, especially during wet years (NS>0.8). Finally, the DOC module was able to describe DOC concentrations measured in the peatland and could be used to assess the impact of rewetting on DOC dynamics at different locations and to identify the factors of control of DOC

  17. Mineralogy and Geochemical Processes of Carbonate Mineral-rich Sulfide Mine Tailings, Zimapan, Mexico

    NASA Astrophysics Data System (ADS)

    McClure, R. J.; Deng, Y.; Loeppert, R.; Herbert, B. E.; Carrillo, R.; Gonzalez, C.

    2009-12-01

    Mining for silver, lead, zinc, and copper in Zimapan, Hidalgo State, Mexico has been ongoing since 1576. High concentrations of heavy metals have been found in several mine tailing heaps in the Zimapan area, with concentrations of arsenic observed as high as 28,690 mg/kg and levels of Pb as high as 2772 mg/kg. Unsecured tailings heaps and associated acid mine drainage has presented tremendous problems to revegetation, water quality, and dust emission control in the Zimapan area. Although acid mine drainage problems related to weathering of sulfide minerals have been extensively studied and are well known, the weathering products of sulfides in areas with a significant presence of carbonate minerals and their effect on the mobility of heavy metals warrant further study. Carbonate minerals are expected to neutralize sulfuric acid produced from weathering of sulfide minerals, however, in the Zimapan area localized areas of pH as low as 1.8 were observed within carbonate mineral-rich tailing heaps. The objectives of this study are to characterize (1) the heavy metal-containing sulfide minerals in the initial tailing materials, (2) the intermediate oxidation products of sulfide minerals within the carbonate-rich tailings, (3) chemical species of heavy metals within pH gradients between 1.8 and 8.2, the approximate natural pH of limestone, and (4) the mobility of soluble and colloidal heavy metals and arsenic within the carbonate-rich tailings. Representative mine tailings and their intermediate oxidation products have been sampled from the Zimapan area. Mineralogical characterization will be conducted with X-ray diffraction, infrared spectroscopy, electron microscopes and microprobes, and chemical methods. Chemical species will be extracted by selective dissolution methods. Preliminary results have identified calcite as the dominant mineral in the tailing heaps with a pH of 7, suggesting non-equilibrium with the acidic weathering products. Other minerals identified in

  18. Efficient degradation of Acid Orange 7 in aqueous solution by iron ore tailing Fenton-like process.

    PubMed

    Zheng, Jianming; Gao, Zhanqi; He, Huan; Yang, Shaogui; Sun, Cheng

    2016-05-01

    An effective method based on iron ore tailing Fenton-like process was studied for removing an azo dye, Acid Orange 7 (AO7) in aqueous solution. Five tailings were characterized by X-ray fluorescence spectroscope (XFS), Brunner-Emmet-Teller (BET) measurement, and Scanning Electron Microscope (SEM). The result of XFS showed that Fe, Si and Ca were the most abundant elements and some toxic heavy metals were also present in the studied tailings. The result of BET analysis indicated that the studied tailings had very low surface areas (0.64-5.68 m(2) g(-1)). The degradation efficiencies of AO7 were positively correlated with the content of iron oxide and cupric oxide, and not related with the BET surface area of the tailings. The co-existing metal elements, particularly Cu, might accelerate the heterogeneous Fenton-like reaction. The effects of other parameters on heterogeneous Fenton-like degradation of AO7 by a converter slag iron tailing (tailing E) which contains highest iron oxide were also investigated. The tailing could be reused 10 times without significant decrease of the catalytic capacity. Very low amount of iron species and almost undetectable toxic elements were leached in the catalytic degradation of AO7 by the tailing E. The reaction products were identified by gas chromatography-mass spectrometry and a possible pathway of AO7 degradation was proposed. This study not only provides an effective method for removing azo dyes in polluted water by employing waste tailings as Fenton-like catalysts, but also uses waste tailings as the secondary resource. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Predicting Tail Buffet Loads of a Fighter Airplane

    NASA Technical Reports Server (NTRS)

    Moses, Robert W.; Pototzky, Anthony S.

    2006-01-01

    Buffet loads on aft aerodynamic surfaces pose a recurring problem on most twin-tailed fighter airplanes: During maneuvers at high angles of attack, vortices emanating from various surfaces on the forward parts of such an airplane (engine inlets, wings, or other fuselage appendages) often burst, immersing the tails in their wakes. Although these vortices increase lift, the frequency contents of the burst vortices become so low as to cause the aft surfaces to vibrate destructively. Now, there exists a new analysis capability for predicting buffet loads during the earliest design phase of a fighter-aircraft program. In effect, buffet pressures are applied to mathematical models in the framework of a finite-element code, complete with aeroelastic properties and working knowledge of the spatiality of the buffet pressures for all flight conditions. The results of analysis performed by use of this capability illustrate those vibratory modes of a tail fin that are most likely to be affected by buffet loads. Hence, the results help in identifying the flight conditions during which to expect problems. Using this capability, an aircraft designer can make adjustments to the airframe and possibly the aerodynamics, leading to a more robust design.

  20. Tree-Substrate Water Relations and Root Development in Tree Plantations Used for Mine Tailings Reclamation.

    PubMed

    Guittonny-Larchevêque, Marie; Bussière, Bruno; Pednault, Carl

    2016-05-01

    Tree water uptake relies on well-developed root systems. However, mine wastes can restrict root growth, in particular metalliferous mill tailings, which consist of the finely crushed ore that remains after valuable metals are removed. Thus, water stress could limit plantation success in reclaimed mine lands. This study evaluates the effect of substrates varying in quality (topsoil, overburden, compost and tailings mixture, and tailings alone) and quantity (50- or 20-cm-thick topsoil layer vs. 1-m plantation holes) on root development and water stress exposure of trees planted in low-sulfide mine tailings under boreal conditions. A field experiment was conducted over 2 yr with two tree species: basket willow ( L.) and hybrid poplar ( Moench × A. Henry). Trees developed roots in the tailings underlying the soil treatments despite tailings' low macroporosity. However, almost no root development occurred in tailings underlying a compost and tailings mixture. Because root development and associated water uptake was not limited to the soil, soil volume influenced neither short-term (water potential and instantaneous transpiration) nor long-term (δC) water stress exposure in trees. However, trees were larger and had greater total leaf area when grown in thicker topsoil. Despite a volumetric water content that always remained above permanent wilting point in the tailings colonized by tree roots, measured foliar water potentials at midday were lower than drought thresholds reported for both tested tree species. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  1. Energy harvesting from the tail beating of a carangiform swimmer using ionic polymer-metal composites.

    PubMed

    Cha, Youngsu; Verotti, Matteo; Walcott, Horace; Peterson, Sean D; Porfiri, Maurizio

    2013-09-01

    In this paper, we study energy harvesting from the beating of a biomimetic fish tail using ionic polymer-metal composites. The design of the biomimetic tail is based on carangiform swimmers and is specifically inspired by the morphology of the heterocercal tail of thresher sharks. The tail is constituted of a soft silicone matrix molded in the form of the heterocercal tail and reinforced by a steel beam of rectangular cross section. We propose a modeling framework for the underwater vibration of the biomimetic tail, wherein the tail is assimilated to a cantilever beam with rectangular cross section and heterogeneous physical properties. We focus on base excitation in the form of a superimposed rotation about a fixed axis and we consider the regime of moderately large-amplitude vibrations. In this context, the effect of the encompassing fluid is described through a hydrodynamic function, which accounts for inertial, viscous and convective phenomena. The model is validated through experiments in which the base excitation is systematically varied and the motion of selected points on the biomimetic tail tracked in time. The feasibility of harvesting energy from an ionic polymer-metal composite attached to the vibrating structure is experimentally and theoretically assessed. The response of the transducer is described using a black-box model, where the voltage output is controlled by the rate of change of the mean curvature. Experiments are performed to elucidate the impact of the shunting resistance, the frequency of the base excitation and the placement of the ionic polymer-metal composite on energy harvesting from the considered biomimetic tail.

  2. Landscape structure and plague occurrence in black-tailed prairie dogs on grasslands of the western USA

    USGS Publications Warehouse

    Collinge, S.K.; Johnson, W.C.; Ray, C.; Matchett, R.; Grensten, J.; Cully, J.F.; Gage, K.L.; Kosoy, M.Y.; Loye, J.E.; Martin, A.P.

    2005-01-01

    Landscape structure influences the abundance and distribution of many species, including pathogens that cause infectious diseases. Black-tailed prairie dogs in the western USA have declined precipitously over the past 100 years, most recently due to grassland conversion and their susceptibility to sylvatic plague. We assembled and analyzed two long-term data sets on plague occurrence in black-tailed prairie dogs to explore the hypotheses that plague occurrence is associated with colony characteristics and landscape context. Our two study areas (Boulder County, Colorado, and Phillips County, Montana) differed markedly in degree of urbanization and other landscape characteristics. In both study areas, we found associations between plague occurrence and landscape and colony characteristics such as the amount of roads, streams and lakes surrounding a prairie dog colony, the area covered by the colony and its neighbors, and the distance to the nearest plague-positive colony. Logistic regression models were similar between the two study areas, with the best models predicting positive effects of proximity to plague-positive colonies and negative effects of road, stream and lake cover on plague occurrence. Taken together, these results suggest that roads, streams and lakes may serve as barriers to plague in black-tailed prairie dog colonies by affecting movement of or habitat quality for plague hosts or for fleas that serve as vectors for the pathogen. The similarity in plague correlates between urban and rural study areas suggests that the correlates of plague are not altered by uniquely urban stressors. ?? Springer 2005.

  3. 14 CFR 27.1565 - Tail rotor.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Tail rotor. 27.1565 Section 27.1565 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... conditions. [Amdt. 27-2, 33 FR 965, Jan. 26, 1968] Rotorcraft Flight Manual and Approved Manual Material ...

  4. 14 CFR 27.1565 - Tail rotor.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Tail rotor. 27.1565 Section 27.1565 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... conditions. [Amdt. 27-2, 33 FR 965, Jan. 26, 1968] Rotorcraft Flight Manual and Approved Manual Material ...

  5. 14 CFR 27.1565 - Tail rotor.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Tail rotor. 27.1565 Section 27.1565 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... conditions. [Amdt. 27-2, 33 FR 965, Jan. 26, 1968] Rotorcraft Flight Manual and Approved Manual Material ...

  6. 14 CFR 27.1565 - Tail rotor.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Tail rotor. 27.1565 Section 27.1565 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... conditions. [Amdt. 27-2, 33 FR 965, Jan. 26, 1968] Rotorcraft Flight Manual and Approved Manual Material ...

  7. 14 CFR 27.1565 - Tail rotor.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Tail rotor. 27.1565 Section 27.1565 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... conditions. [Amdt. 27-2, 33 FR 965, Jan. 26, 1968] Rotorcraft Flight Manual and Approved Manual Material ...

  8. Weighted Kolmogorov-Smirnov test: Accounting for the tails

    NASA Astrophysics Data System (ADS)

    Chicheportiche, Rémy; Bouchaud, Jean-Philippe

    2012-10-01

    Accurate goodness-of-fit tests for the extreme tails of empirical distributions is a very important issue, relevant in many contexts, including geophysics, insurance, and finance. We have derived exact asymptotic results for a generalization of the large-sample Kolmogorov-Smirnov test, well suited to testing these extreme tails. In passing, we have rederived and made more precise the approximate limit solutions found originally in unrelated fields, first in [L. Turban, J. Phys. A1361-644710.1088/0305-4470/25/3/008 25, 127 (1992)] and later in [P. L. Krapivsky and S. Redner, Am. J. Phys.AJPIAS0002-950510.1119/1.18152 64, 546 (1996)].

  9. Efficient bootstrap estimates for tail statistics

    NASA Astrophysics Data System (ADS)

    Breivik, Øyvind; Aarnes, Ole Johan

    2017-03-01

    Bootstrap resamples can be used to investigate the tail of empirical distributions as well as return value estimates from the extremal behaviour of the sample. Specifically, the confidence intervals on return value estimates or bounds on in-sample tail statistics can be obtained using bootstrap techniques. However, non-parametric bootstrapping from the entire sample is expensive. It is shown here that it suffices to bootstrap from a small subset consisting of the highest entries in the sequence to make estimates that are essentially identical to bootstraps from the entire sample. Similarly, bootstrap estimates of confidence intervals of threshold return estimates are found to be well approximated by using a subset consisting of the highest entries. This has practical consequences in fields such as meteorology, oceanography and hydrology where return values are calculated from very large gridded model integrations spanning decades at high temporal resolution or from large ensembles of independent and identically distributed model fields. In such cases the computational savings are substantial.

  10. A red-tailed hawk at KSC

    NASA Technical Reports Server (NTRS)

    2000-01-01

    At KSC, a red-tailed hawk waits on top of a utility pole for the slightest movement in the grass below. It feeds mostly on small rodents. Ranging in height from 18 inches to 25 inches, the species has a stocky build with a whitish breast and rust-colored tail. It has a high-pitched descending scream with a hoarse quality. The hawk inhabits mainly deciduous forest and adjacent open country from Alaska and Nova Scotia south to Panama. KSC shares a boundary with the Merritt Island National Wildlife Refuge, which encompasses 92,000 acres that are a habitat for more than 331 species of birds, 31 mammals, 117 fishes, and 65 amphibians and reptiles. The marshes and open water of the refuge provide wintering areas for 23 species of migratory waterfowl, as well as a year-round home for great blue herons, great egrets, wood storks, cormorants, brown pelicans and other species of marsh and shore birds, as well as a variety of insects.

  11. A red-tailed hawk at KSC

    NASA Technical Reports Server (NTRS)

    2000-01-01

    From the top of a utility pole, a red-tailed hawk launches into flight, perhaps after spotting prey, typically a small rodent. Ranging in height from 18 inches to 25 inches, the species has a stocky build with a whitish breast and rust-colored tail. It has a high-pitched descending scream with a hoarse quality. The hawk inhabits mainly deciduous forest and adjacent open country from Alaska and Nova Scotia south to Panama. KSC shares a boundary with the Merritt Island National Wildlife Refuge, which encompasses 92,000 acres that are a habitat for more than 331 species of birds, 31 mammals, 117 fishes, and 65 amphibians and reptiles. The marshes and open water of the refuge provide wintering areas for 23 species of migratory waterfowl, as well as a year-round home for great blue herons, great egrets, wood storks, cormorants, brown pelicans and other species of marsh and shore birds, as well as a variety of insects.

  12. Power law tails in phylogenetic systems.

    PubMed

    Qin, Chongli; Colwell, Lucy J

    2018-01-23

    Covariance analysis of protein sequence alignments uses coevolving pairs of sequence positions to predict features of protein structure and function. However, current methods ignore the phylogenetic relationships between sequences, potentially corrupting the identification of covarying positions. Here, we use random matrix theory to demonstrate the existence of a power law tail that distinguishes the spectrum of covariance caused by phylogeny from that caused by structural interactions. The power law is essentially independent of the phylogenetic tree topology, depending on just two parameters-the sequence length and the average branch length. We demonstrate that these power law tails are ubiquitous in the large protein sequence alignments used to predict contacts in 3D structure, as predicted by our theory. This suggests that to decouple phylogenetic effects from the interactions between sequence distal sites that control biological function, it is necessary to remove or down-weight the eigenvectors of the covariance matrix with largest eigenvalues. We confirm that truncating these eigenvectors improves contact prediction.

  13. Tail Docking of Canine Puppies: Reassessment of the Tail's Role in Communication, the Acute Pain Caused by Docking and Interpretation of Behavioural Responses.

    PubMed

    Mellor, David J

    2018-05-31

    Laws, regulations and professional standards increasingly aim to ban or restrict non-therapeutic tail docking in canine puppies. These constraints have usually been justified by reference to loss of tail participation in communication between dogs, the acute pain presumed to be caused during docking itself, subsequent experiences of chronic pain and heightened pain sensitivity, and the occurrence of other complications. These areas are reconsidered here. First, a scientifically robust examination of the dynamic functional foundations, sensory components and key features of body language that are integral to canine communication shows that the role of the tail has been greatly underestimated. More specifically, it shows that tail behaviour is so embedded in canine communication that docking can markedly impede unambiguous interactions between different dogs and between dogs and people. These interactions include the expression of wide ranges of both negative and positive emotions, moods and intentions that are of daily significance for dog welfare. Moreover, all docked dogs may experience these impediments throughout their lives, which challenges assertions by opponents to such bans or restrictions that the tail is a dispensable appendage. Second, and in contrast, a re-examination of the sensory capacities of canine puppies reveals that they cannot consciously experience acute or chronic pain during at least the first week after birth, which is when they are usually docked. The contrary view is based on questionable between-species extrapolation of information about pain from neurologically mature newborns such as calves, lambs, piglets and human infants, which certainly can consciously experience pain in response to injury, to neurologically immature puppies which remain unconscious and therefore unable to experience pain until about two weeks after birth. Third, underpinned by the incorrect conclusion that puppies are conscious at the usual docking age, it is

  14. Failure Analysis on Tail Rotor Teeter Pivot Bolt on a Helicopter

    NASA Astrophysics Data System (ADS)

    Qiang, WANG; Zi-long, DONG

    2018-03-01

    Tail rotor teeter pivot bolt of a helicopter fractured when in one flight. Failure analysis on the bolt was finished in laboratory. Macroscopic observation of the tailor rotor teeter pivot bolt, macro and microscopic inspection on the fracture surface of the bolt was carried out. Chemical components and metallurgical structure was also carried out. Experiment results showed that fracture mode of the tail rotor teeter pivot bolt is fatigue fracture. Fatigue area is over 80% of the total fracture surface, obvious fatigue band characteristics can be found at the fracture face. According to the results were analyzed from the macroscopic and microcosmic aspects, fracture reasons of the tail rotor teeter pivot bolt were analyzed in detail

  15. Electron cyclotron maser instability in the solar corona - The role of superthermal tails

    NASA Technical Reports Server (NTRS)

    Vlahos, L.; Sharma, R. R.

    1985-01-01

    The effect of a superthermal component of electrons on the loss-cone-driven electron cyclotron maser instability is analyzed. It is found that for a superthermal tail with temperature about 10 KeV, the first harmonic (X- and O-mode) is suppressed for n(t)/n(r) of about 1 (n/t/ and n/r/ are the densities of superthermal tail and loss-cone electrons) and the second harmonic (X- and O-modes) is suppressed for n(t)/n(r) less than about 0.1. A qualitative discussion on the formation of superthermal tails is presented and it is suggested that superthermal tails play an important role on the observed or available power, at microwave frequencies, from the electron cyclotron maser instability in the solar corona.

  16. Cloning of the short-tailed Gyeongju Donggyeong dog via SCNT: conserving phenotypic inheritance.

    PubMed

    Choi, Yoo Bin; Kim, Geon A; Oh, Hyun Ju; Kim, Min Jung; Jo, Young Kwang; Setyawan, Erif Maha Nugraha; Lee, Seok Hee; Lee, Byeong Chun

    2016-02-01

    Somatic cell nuclear transfer is a useful tool to maintain genetic information of animals. The Gyeongju Donggyeong dog is a breed registered as natural monument in Korea. The unique feature of the Donggyeong dog is its tail, as the Donggyeong dog can be classified as either short tailed or tailless. The aim of this study was to preserve the Donggyeong dog's unique feature by cloning. Fibroblasts were obtained from a short-tailed Donggyeong dog. In vivo matured oocytes were enucleated, microinjected with a donor cell and fused electrically. Reconstructed embryos were transferred to six recipient dogs. One surrogate became pregnant, and one short-tailed Donggyeong dog was delivered. This study demonstrated that the phenotype of the Donggyeong dog could be conserved by somatic cell nuclear transfer.

  17. ON THE POLARIZATION PROPERTIES OF MAGNETAR GIANT FLARE PULSATING TAILS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang, Yuan-Pei; Zhang, Bing, E-mail: yypspore@gmail.com, E-mail: zhang@physics.unlv.edu

    Three giant flares have been detected so far from soft gamma-ray repeaters, each characterized by an initial short hard spike and a pulsating tail. The observed pulsating tails are characterized by a duration of ∼100 s, an isotropic energy of ∼10{sup 44} erg, and a pulse period of a few seconds. The pulsating tail emission likely originates from the residual energy after the intense energy release during the initial spike, which forms a trapped fireball composed of a photon-pair plasma in a closed-field-line region of the magnetars. Observationally the spectra of pulsating tails can be fitted by the superposition ofmore » a thermal component and a power-law component, with the thermal component dominating the emission in the early and late stages of the pulsating-tail observations. In this paper, assuming that the trapped fireball is from a closed-field-line region in the magnetosphere, we calculate the atmospheric structure of the optically thick trapped fireball and the polarization properties of the trapped fireball. By properly treating the photon propagation in a hot, highly magnetized, electron–positron pair plasma, we tally photons in two modes (O mode and E mode) at a certain observational angle through Monte Carlo simulations. Our results suggest that the polarization degree depends on the viewing angle with respect to the magnetic axis of the magnetar, and can be as high as Π ≃ 30% in the 1–30 keV band, and Π ≃ 10% in the 30–100 keV band, if the line of sight is perpendicular to the magnetic axis.« less

  18. Geochemical Weathering Increases Lead Bioaccessibility in Semi-Arid Mine Tailings

    PubMed Central

    Hayes, Sarah M.; Webb, Sam M.; Bargar, John R.; O'Day, Peggy A.; Maier, Raina M.; Chorover, Jon

    2012-01-01

    Mine tailings can host elevated concentrations of toxic metal(loid)s that represent a significant hazard to surrounding communities and ecosystems. Eolian transport, capable of translocating small (micrometer-sized) particles, can be the dominant mechanism of toxic metal dispersion in arid or semi-arid landscapes. Human exposure to metals can then occur via direct inhalation or ingestion of particulates. The fact that measured doses of total lead (Pb) in geomedia correlate poorly with blood Pb levels highlights a need to better resolve the precise distribution of molecularly-speciated metal-bearing phases in the complex particle mixtures. Species distribution controls bioaccessibility, thereby directly impacting health risk. This study seeks to correlate Pb-containing particle size and mineral composition with lability and bioaccessibility in mine tailings subjected to weathering in a semi-arid environment. We employed X-ray absorption spectroscopy (XAS) and X-ray fluorescence (XRF), coupled with sequential chemical extractions, to study Pb speciation in tailings from the semi-arid Arizona Klondyke State Superfund Site. Representative samples ranging in pH from 2.6 to 5.4 were selected for in-depth study of Pb solid-phase speciation. The principle lead-bearing phase was plumbojarosite (PbFe6(SO4)4(OH)12), but anglesite (PbSO4) and iron oxide-sorbed Pb were also observed. Anglesite, the most bioavailable mineral species of lead identified in this study, was enriched in surficial tailings samples, where Pb concentrations in the clay size fraction were 2–3 times higher by mass relative to bulk. A mobile and bioaccessible Pb phase accumulates in surficial tailings, with a corresponding increase in risk of human exposure to atmospheric particles. PMID:22553941

  19. Presence of Antibodies to Leptospira spp. in Black-tailed Prairie Dogs ( Cynomys ludovicianus ) and Beavers ( Castor canadensis ) in Northwestern Mexico.

    PubMed

    López-Pérez, Andrés M; Carreón-Arroyo, Gerardo; Atilano, Daniel; Vigueras-Galván, Ana L; Valdez, Carlos; Toyos, Daniel; Mendizabal, Daniel; López-Islas, Jonathan; Suzán, Gerardo

    2017-10-01

    Leptospires are widespread spirochete bacteria that infect mammals, including rodents and humans. We investigated the presence of Leptospira antibodies in two species of rodents from San Pedro River Basin (SPRB) in northwestern Mexico as part of the black-tailed prairie dog ( Cynomys ludovicianus ) monitoring plan and the North American beaver ( Castor canadensis ) reintroduction program. We sampled a total of 26 black-tailed prairie dogs and three beavers during October-November 2015. We detected antibodies against Leptospira spp. by microagglutination test in 12 (46%) prairie dogs and in two (67%) beavers. The antibody titers for seropositive rodents varied from 1:100 to 1:200, but none of the animals showed clinical signs of disease. We found seven Leptospira spp. serogroups (Autumnalis, Australis, Bataviae, Canicola, Celledoni, Grippotyphosa, and Sejroe) circulating in rodent species in SPRB. We did not find any differences between sex and age concerning Leptospira-positive rodents. Our findings suggest the presence of endemic cycles and potential risks of Leptospira infection in both species from SPRB. Although the impact of this infection on threatened species remains unclear, human activities and environmental stress might facilitate the emergence or reemergence of leptospirosis disease as has been reported elsewhere.

  20. The tail of the Ordovician fish Sacabambaspis.

    PubMed

    Pradel, Alan; Sansom, Ivan J; Gagnier, Pierre-Yves; Cespedes, Ricardo; Janvier, Philippe

    2007-02-22

    The tail of the earliest known articulated fully skeletonized vertebrate, the arandaspid Sacabambaspis from the Ordovician of Bolivia, is redescribed on the basis of further preparation of the only specimen in which it is most extensively preserved. The first, but soon discarded, reconstruction, which assumed the presence of a long horizontal notochordal lobe separating equal sized dorsal and ventral fin webs, appears to have considerable merit. Although the ventral web is significantly smaller than the dorsal one, the presence of a very long notochordal lobe bearing a small terminal web is confirmed. The discrepancy in the size of the ventral and dorsal webs rather suggests that the tail was hypocercal, a condition that would better accord with the caudal morphology of the living agnathans and the other jawless stem gnathostomes.