System Description for Tank 241-AZ-101 Waste Retrieval Data Acquisition System

DOE Office of Scientific and Technical Information (OSTI.GOV)

ROMERO, S.G.

2000-01-10

Describes the hardware and software for the AZ-101 Mixer Pump Data Acquisition System. The purpose of the tank 241-AZ-101 retrieval system Data Acquisition System (DAS) is to provide monitoring and data acquisition of key parameters in order to confirm the effectiveness of the mixer pumps utilized for suspending solids in the tank. The suspension of solids in Tank 241-AZ-101 is necessary for pretreatment of the neutralized current acid waste (NCAW), and eventual disposal as glass via the Hanford Waste Vitrification Plant.

Simulation of Hanford Tank 241-C-106 Waste Release into Tank 241-Y-102

DOE Office of Scientific and Technical Information (OSTI.GOV)

KP Recknagle; Y Onishi

Waste stored in Hdord single-shell Tank 241-C-106 will be sluiced with a supernatant liquid from doubIe-shell Tank 241 -AY- 102 (AY-1 02) at the U.S. Department of Energy's Har@ord Site in Eastern Washington. The resulting slurry, containing up to 30 wtYo solids, will then be transferred to Tank AY-102. During the sluicing process, it is important to know the mass of the solids being transferred into AY- 102. One of the primary instruments used to measure solids transfer is an E+ densitometer located near the periphery of the tank at riser 15S. This study was undert.dcen to assess how wellmore » a densitometer measurement could represent the total mass of soiids transferred if a uniform lateral distribution was assumed. The study evaluated the C-1 06 slurry mixing and accumulation in Tank AY- 102 for the following five cases: Case 1: 3 wt'%0 slurry in 6.4-m AY-102 waste Case 2: 3 w-t% slurry in 4.3-m AY-102 waste Case 3: 30 wtYo slurry in 6.4-m AY-102 waste Case 4: 30 wt% slurry in 4.3-m AY-102 waste Case 5: 30 wt% slurry in 5. O-m AY-102 waste. The tirne-dependent, three-dimensional, TEMPEST computer code was used to simulate solid deposition and accumulation during the injection of the C-106 slurry into AY-102 through four injection nozzles. The TEMPEST computer code was applied previously to other Hanford tanks, AP-102, SY-102, AZ-101, SY-101, AY-102, and C-106, to model tank waste mixing with rotating pump jets, gas rollover events, waste transfer from one tank to another, and pump-out retrieval of the sluiced waste. The model results indicate that the solid depth accumulated at the densitometer is within 5% of the average depth accumulation. Thus the reading of the densitometer is expected to represent the total mass of the transferred solids reasonably well.« less

CESIUM REMOVAL FROM TANKS 241-AN-103 & 241-SX-105 & 241-AZ-101 & 241AZ-102 COMPOSITE FOR TESTING IN BENCH SCALE STEAM REFORMER

DOE Office of Scientific and Technical Information (OSTI.GOV)

DUNCAN JB; HUBER HJ

2011-04-21

This report documents the preparation of three actual Hanford tank waste samples for shipment to the Savannah River National Laboratory (SRNL). Two of the samples were dissolved saltcakes from tank 241-AN-103 (hereafter AN-103) and tank 241-SX-105 (hereafter SX-105); one sample was a supernate composite from tanks 241-AZ-101 and 241-AZ-102 (hereafter AZ-101/102). The preparation of the samples was executed following the test plans LAB-PLAN-10-00006, Test Plan for the Preparation of Samples from Hanford Tanks 241-SX-105, 241-AN-103, 241-AN-107, and LAB-PLN-l0-00014, Test Plan for the Preparation of a Composite Sample from Hanford Tanks 241-AZ-101 and 241-AZ-102 for Steam Reformer Testing at the Savannahmore » River National Laboratory. All procedural steps were recorded in laboratory notebook HNF-N-274 3. Sample breakdown diagrams for AN-103 and SX-105 are presented in Appendix A. The tank samples were prepared in support of a series of treatability studies of the Fluidized Bed Steam Reforming (FBSR) process using a Bench-Scale Reformer (BSR) at SRNL. Tests with simulants have shown that the FBSR mineralized waste form is comparable to low-activity waste glass with respect to environmental durability (WSRC-STI-2008-00268, Mineralization of Radioactive Wastes by Fluidized Bed Steam Reforming (FBSR): Comparisons to Vitreous Waste Forms and Pertinent Durability Testing). However, a rigorous assessment requires long-term performance data from FBSR product formed from actual Hanford tank waste. Washington River Protection Solutions, LLC (WRPS) has initiated a Waste Form Qualification Program (WP-5.2.1-2010-001, Fluidized Bed Steam Reformer Low-level Waste Form Qualification) to gather the data required to demonstrate that an adequate FBSR mineralized waste form can be produced. The documentation of the selection process of the three tank samples has been separately reported in RPP-48824, Sample Selection Process for Bench-Scale Steam Reforming Treatability Studies

Tank 241-AZ-101 Mixer Pump Test Vapor Sampling and Analysis Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

TEMPLETON, A.M.

2000-03-06

This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for vapor samples obtained during the operation of mixer pumps in tank 241-AZ-101. The primary purpose of the mixer pump test (MPT) is to demonstrate that the two 300 horsepower mixer pumps installed in tank 241-AZ-101 can mobilize the settled sludge so that it can be retrieved for treatment and vitrification. Sampling will be performed in accordance with Tank 241-AZ-101 Mixer Pump Test Data Quality Objective (Banning 1999) and Data Quality Objectives for Regulatory Requirements for Hazardous and Radioactive Air Emissionsmore » Sampling and Analysis (Mulkey 1999). The sampling will verify if current air emission estimates used in the permit application are correct and provide information for future air permit applications.« less

Tank 241-AZ-101 Mixer Pump Test Vapor Sampling and Analysis Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

TEMPLETON, A.M.

2000-01-31

This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for vapor samples obtained during the operation of mixer pumps in tank 241-AZ-101. The primary purpose of the mixer pump test (MPT) is to demonstrate that the two 300 horsepower mixer pumps installed in tank 241-AZ-101 can mobilize the settled sludge so that it can be retrieved for treatment and vitrification Sampling will be performed in accordance with Tank 241-AZ-101 Mixer Pump Test Data Quality Objective (Banning 1999) and Data Quality Objectives for Regulatory Requirements for Hazardous and Radioactive Air Emissionsmore » Sampling and Analysis (Mulkey 1999). The sampling will verify if current air emission estimates used in the permit application are correct and provide information for future air permit applications.« less

Tank 241-AZ-101 Mixer Pump Test Vapor Sampling and Analysis Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

TEMPLETON, A.M.

2000-04-10

This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for vapor samples obtained during the operation of mixer pumps in tank 241-AZ-101. The primary purpose of the mixer pump test (MPT) is to demonstrate that the two 300 horsepower mixer pumps installed in tank 241-AZ-101 can mobilize the settled sludge so that it can be retrieved for treatment and vitrification. Sampling will be performed in accordance with Tank 241-AZ-101 Mixer Pump Test Data Quality Objective (Banning 1999) and Data Quality Objectives for Regulatory Requirements for Hazardous and Radioactive Air Emissionsmore » Sampling and Analysis (Mulkey 1999). The sampling will verify if current air emission estimates used in the permit application are correct and provide information for future air permit applications.« less

CESIUM REMOVAL FROM TANKS 241-AN-103 & 241-SX-105 & 241-AZ-101/102 COMPOSITE FOR TESTING IN BENCH SCALE STEAM REFORMER

DOE Office of Scientific and Technical Information (OSTI.GOV)

DUNCAN JB; HUBER HJ

2011-06-08

This report documents the preparation of three actual Hanford tank waste samples for shipment to the Savannah River National Laboratory (SRNL). Two of the samples were dissolved saltcakes from tank 241-AN-103 (hereafter AN-103) and tank 241-SX-105 (hereafter SX-105); one sample was a supernate composite from tanks 241-AZ-101 and 241-AZ-102 (hereafter AZ-101/102). The preparation of the samples was executed following the test plans LAB-PLAN-10-00006, Test Plan for the Preparation of Samples from Hanford Tanks 241-SX-105, 241-AN-103, 241-AN-107, and LAB-PLN-10-00014, Test Plan for the Preparation of a Composite Sample from Hanford Tanks 241-AZ-101 and 241-AZ-102 for Steam Reformer Testing at the Savannahmore » River National Laboratory. All procedural steps were recorded in laboratory notebook HNF-N-274 3. Sample breakdown diagrams for AN-103 and SX-105 are presented in Appendix A. The tank samples were prepared in support of a series of treatability studies of the Fluidized Bed Steam Reforming (FBSR) process using a Bench-Scale Reformer (BSR) at SRNL. Tests with simulants have shown that the FBSR mineralized waste form is comparable to low-activity waste glass with respect to environmental durability (WSRC-STI-2008-00268, Mineralization of Radioactive Wastes by Fluidized Bed Steam Reforming (FBSR): Comparisons to Vitreous Waste Forms and Pertinent Durability Testing). However, a rigorous assessment requires long-term performance data from FB SR product formed from actual Hanford tank waste. Washington River Protection Solutions, LLC (WRPS) has initiated a Waste Form Qualification Program (WP-S.2.1-20 1 0-00 1, Fluidized Bed Steam Reformer Low-level Waste Form Qualification) to gather the data required to demonstrate that an adequate FBSR mineralized waste form can be produced. The documentation of the selection process of the three tank samples has been separately reported in RPP-48824, 'Sample Selection Process for Bench-Scale Steam Reforming Treatability Studies

System Design Description for the SY-101 Hydrogen Mitigation Test Project Data Acquisition and Control System (DACS-1)

DOE Office of Scientific and Technical Information (OSTI.GOV)

ERMI, A.M.

2000-01-24

This document describes the hardware and software of the computer subsystems for the Data Acquisition and Control System (DACS) used in mitigation tests conducted on waste tank 241-SY-101 at the Hanford Nuclear Reservation.

Analytical test results for archived core composite samples from tanks 241-TY-101 and 241-TY-103

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beck, M.A.

1993-07-16

This report describes the analytical tests performed on archived core composite samples form a 1.085 sampling of the 241-TY-101 (101-TY) and 241-TY-103 (103-TY) single shell waste tanks. Both tanks are suspected of containing quantities of ferrocyanide compounds, as a result of process activities in the late 1950`s. Although limited quantities of the composite samples remained, attempts were made to obtain as much analytical information as possible, especially regarding the chemical and thermal properties of the material.

Minutes of the Tank Waste Science Panel Meeting March 25--27, 1992. Hanford Tank Safety Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schutz, W W; Consultant, Wellington, Delaware; Strachan, D M

Discussions from the seventh meeting of the Tank Waste Science are presented in Colorado. The subject areas included the generation of gases in Tank 241-SY-101, the possible use of sonication as a mitigation method, and analysis for organic constituents in core samples. Results presented and discussed include: Ferrocyanides appear to be rapidly dissolved in 1M NaOH; upon standing in the laboratory at ambient conditions oxalate precipitates from simulated wastes containing HEDTA. This suggests that one of the main components in the solids in Tank 241-SY-101 is oxalate; hydrogen evolved from waste samples from Tank 241-SY-101 is five times that observedmore » in the off gas from the tank; data suggest that mitigation of Tank 241-SY-101 will not cause a high release of dissolved N{sub 2}O; when using a slurry for radiation studies, a portion of the generated gases is very difficult to remove. To totally recover the generated gases, the solids must first be dissolved. This result may have an impact on mitigation by mixing if the gases are not released. Using {sup 13}C-labeled organics in thermal degradation studies has allowed researchers to illucidate much of the kinetic mechanism for the degradation of HEDTA and glycolate. In addition to some of the intermediate, more complex organic species, oxalate, formate, and CO{sub 2} were identified; and analytic methods for organics in radioactive complex solutions such as that found in Tank 241-SY-101 have been developed and others continue to be developed.« less

A Discussion of SY-101 Crust Gas Retention and Release Mechanisms

DOE Office of Scientific and Technical Information (OSTI.GOV)

SD Rassat; PA Gauglitz; SM Caley

1999-02-23

The flammable gas hazard in Hanford waste tanks was made an issue by the behavior of double-shell Tank (DST) 241-SY-101 (SY-101). Shortly after SY-101 was filled in 1980, the waste level began rising periodically, due to the generation and retention of gases within the slurry, and then suddenly dropping as the gases were released. An intensive study of the tank's behavior revealed that these episodic releases posed a safety hazard because the released gas was flammable, and, in some cases, the volume of gas released was sufficient to exceed the lower flammability limit (LFL) in the tank headspace (Allemann etmore » al. 1993). A mixer pump was installed in SY-101 in late 1993 to prevent gases from building up in the settled solids layer, and the large episodic gas releases have since ceased (Allemann et al. 1994; Stewart et al. 1994; Brewster et al. 1995). However, the surface level of SY-101 has been increasing since at least 1995, and in recent months the level growth has shown significant and unexpected acceleration. Based on a number of observations and measurements, including data from the void fraction instrument (VFI), we have concluded that the level growth is caused largely by increased gas retention in the floating crust. In September 1998, the crust contained between about 21 and 43% void based on VFI measurements (Stewart et al. 1998). Accordingly, it is important to understand the dominant mechanisms of gas retention, why the gas retention is increasing, and whether the accelerating level increase will continue, diminish or even reverse. It is expected that the retained gas in the crust is flammable, with hydrogen as a major constituent. This gas inventory would pose a flammable gas hazard if it were to release suddenly. In May 1997, the mechanisms of bubble retention and release from crust material were the subject of a workshop. The evaluation of the crust and potential hazards assumed a more typical void of roughly 15% gas. It could be similar to

Hanford Double-Shell Tank Extent-of-Condition Construction Review

DOE Office of Scientific and Technical Information (OSTI.GOV)

Venetz, Theodore J.; Johnson, Jeremy M.; Gunter, Jason R.

2013-11-14

During routine visual inspections of Hanford double-shell waste tank 241-AY-102 (AY-102), anomalies were identified on the annulus floor which resulted in further evaluations. Following a formal leak assessment in October 2012, Washington River Protection Solutions, LLC (WRPS) determined that the primary tank of AY-102 was leaking. The formal leak assessment, documented in RPP-ASMT-53793,Tank 241-AY-102 Leak Assessment Report, identified first-of-a-kind construction difficulties and trial-and-error repairs as major contributing factors to tank failure. To determine if improvements in double-shell tank (DST) construction occurred after construction of tank AY-102, a detailed review and evaluation of historical construction records were performed for the firstmore » three DST tank farms constructed, which included tanks 241-AY-101, 241-AZ-101, 241-AZ-102, 241-SY-101, 241-SY-102, and 241-SY-103. The review for these six tanks involved research and review of dozens of boxes of historical project documentation. These reviews form a basis to better understand the current condition of the three oldest Hanford DST farms. They provide a basis for changes to the current tank inspection program and also provide valuable insight into future tank use decisions. If new tanks are constructed in the future, these reviews provide valuable "lessons-learned" information about expected difficulties as well as construction practices and techniques that are likely to be successful.« less

EFFECTS OF CHEMISTRY AND OTHER VARIABLES ON CORROSION AND STRESS CORROSION CRACKING IN HANFORD DOUBLE SHELL TANKS

DOE Office of Scientific and Technical Information (OSTI.GOV)

BROWN MH

2008-11-13

Laboratory testing was performed to develop a comprehensive understanding of the corrosivity of the tank wastes stored in Double-Shell Tanks using simulants primarily from Tanks 241-AP-105, 241-SY-103 and 241-AW-105. Additional tests were conducted using simulants of the waste stored in 241-AZ-102, 241-SY-101, 241-AN-107, and 241-AY-101. This test program placed particular emphasis on defining the range of tank waste chemistries that do not induce the onset of localized forms of corrosion, particularly pitting and stress corrosion cracking. This document summarizes the key findings of the research program.

Tank 241-AZ-102 Privatization Push Mode Core Sampling and Analysis Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

RASMUSSEN, J.H.

1999-08-02

This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for samples obtained from tank 241-AZ-102. The purpose of this sampling event is to obtain information about the characteristics of the contents of 241-AZ-102 required to satisfy the Data Quality Objectives For TWRS Privatization Phase I: Confirm Tank TIS An Appropriate Feed Source For High-Level Waste Feed Batch X(HLW DQO) (Nguyen 1999a), Data Quality Objectives For TWRS Privatization Phase 1: Confirm Tank TIS An Appropriate Feed Source For Low-Activity Waste Feed Batch X (LAW DQO) (Nguyen 1999b), Low Activity Waste andmore » High Level Waste Feed Data Quality Objectives (L&H DQO) (Patello et al. 1999) and Characterization Data Needs for Development, Design, and Operation of Retrieval Equipment Developed through the Data Quality Objective Process (Equipment DQO) (Bloom 1996). The Tank Characterization Technical Sampling Basis document (Brown et al. 1998) indicates that these issues, except the Equipment DQO apply to tank 241-AZ-102 for this sampling event. The Equipment DQO is applied for shear strength measurements of the solids segments only. Poppiti (1999) requires additional americium-241 analyses of the sludge segments. Brown et al. (1998) also identify safety screening, regulatory issues and provision of samples to the Privatization Contractor(s) as applicable issues for this tank. However, these issues will not be addressed via this sampling event. Reynolds et al. (1999) concluded that information from previous sampling events was sufficient to satisfy the safety screening requirements for tank 241 -AZ-102. Push mode core samples will be obtained from risers 15C and 24A to provide sufficient material for the chemical analyses and tests required to satisfy these data quality objectives. The 222-S Laboratory will extrude core samples, composite the liquids and solids, perform chemical

241-AZ Tank Farm Construction Extent of Condition Review for Tank Integrity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnes, Travis J.; Boomer, Kayle D.; Gunter, Jason R.

2013-07-30

This report provides the results of an extent of condition construction history review for tanks 241-AZ-101 and 241-AZ-102. The construction history of the 241-AZ tank farm has been reviewed to identify issues similar to those experienced during tank AY-102 construction. Those issues and others impacting integrity are discussed based on information found in available construction records, using tank AY-102 as the comparison benchmark. In the 241-AZ tank farm, the second DST farm constructed, both refractory quality and tank and liner fabrication were improved.

Inorganic, Radioisotopic, and Organic Analysis of 241-AP-101 Tank Waste

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fiskum, S.K.; Bredt, P.R.; Campbell, J.A.

2000-10-17

Battelle received five samples from Hanford waste tank 241-AP-101, taken at five different depths within the tank. No visible solids or organic layer were observed in the individual samples. Individual sample densities were measured, then the five samples were mixed together to provide a single composite. The composite was homogenized and representative sub-samples taken for inorganic, radioisotopic, and organic analysis. All analyses were performed on triplicate sub-samples of the composite material. The sample composite did not contain visible solids or an organic layer. A subsample held at 10 C for seven days formed no visible solids.

Structural analysis of color video camera installation on tank 241AW101 (2 Volumes)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Strehlow, J.P.

1994-08-24

A video camera is planned to be installed on the radioactive storage tank 241AW101 at the DOE` s Hanford Site in Richland, Washington. The camera will occupy the 20 inch port of the Multiport Flange riser which is to be installed on riser 5B of the 241AW101 (3,5,10). The objective of the project reported herein was to perform a seismic analysis and evaluation of the structural components of the camera for a postulated Design Basis Earthquake (DBE) per the reference Structural Design Specification (SDS) document (6). The detail of supporting engineering calculations is documented in URS/Blume Calculation No. 66481-01-CA-03 (1).

Tank 241-T-204, core 188 analytical results for the final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nuzum, J.L.

TANK 241-T-204, CORE 188, ANALYTICAL RESULTS FOR THE FINAL REPORT. This document is the final laboratory report for Tank 241 -T-204. Push mode core segments were removed from Riser 3 between March 27, 1997, and April 11, 1997. Segments were received and extruded at 222-8 Laboratory. Analyses were performed in accordance with Tank 241-T-204 Push Mode Core Sampling and analysis Plan (TRAP) (Winkleman, 1997), Letter of instruction for Core Sample Analysis of Tanks 241-T-201, 241- T-202, 241-T-203, and 241-T-204 (LAY) (Bell, 1997), and Safety Screening Data Qual@ Objective (DO) ODukelow, et al., 1995). None of the subsamples submitted for totalmore » alpha activity (AT) or differential scanning calorimetry (DC) analyses exceeded the notification limits stated in DO. The statistical results of the 95% confidence interval on the mean calculations are provided by the Tank Waste Remediation Systems Technical Basis Group and are not considered in this report.« less

Safety equipment list for the 241-SY-101 RAPID mitigation project

DOE Office of Scientific and Technical Information (OSTI.GOV)

MORRIS, K.L.

1999-06-29

This document provides the safety classification for the safety (safety class and safety RAPID Mitigation Project. This document is being issued as the project SEL until the supporting authorization basis documentation, this document will be superseded by the TWRS SEL (LMHC 1999), documentation istlralized. Upon implementation of the authorization basis significant) structures, systems, and components (SSCS) associated with the 241-SY-1O1 which will be updated to include the information contained herein.

Human-machine interface (HMI) report for 241-SY-101 data acquisition [and control] system (DACS) upgrade study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Truitt, R.W.

1997-10-22

This report provides an independent evaluation of information for a Windows based Human Machine Interface (HMI) to replace the existing DOS based Iconics HMI currently used in the Data Acquisition and Control System (DACS) used at Tank 241-SY-101. A fundamental reason for this evaluation is because of the difficulty of maintaining the system with obsolete, unsupported software. The DACS uses a software operator interface (Genesis for DOS HMI) that is no longer supported by its manufacturer, Iconics. In addition to its obsolescence, it is complex and difficult to train additional personnel on. The FY 1997 budget allocated $40K for phasemore » 1 of a software/hardware upgrade that would have allowed the old DOS based system to be replaced by a current Windows based system. Unfortunately, budget constraints during FY 1997 has prompted deferral of the upgrade. The upgrade needs to be performed at the earliest possible time, before other failures render the system useless. Once completed, the upgrade could alleviate other concerns: spare pump software may be able to be incorporated into the same software as the existing pump, thereby eliminating the parallel path dilemma; and the newer, less complex software should expedite training of future personnel, and in the process, require that less technical time be required to maintain the system.« less

Tank 241-AN-101, grab samples, 1AN-98-1, 1AN-98-2 and 1AN-98-3 analytical results for the final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

FULLER, R.K.

1999-02-24

This document is the final report for tank 241-AN-101 grab samples. Three grab samples 1AN-98-1, 1AN-98-2 and 1AN-98-3 were taken from riser 16 of tank 241-AN-101 on April 8, 1998 and received by the 222-S Laboratory on April 9, 1998. Analyses were performed in accordance with the ''Compatability Grab Sampling and Analysis Plan'' (TSAP) and the ''Data Quality Objectives for Tank Farms Waste Compatability Program'' (DQO). The analytical results are presented in the data summary report. No notification limits were exceeded.

TEST PLAN AND PROCEDURE FOR THE EXAMINATION OF TANK 241-AY-101 MULTI-PROBE CORROSION MONITORING SYSTEM

DOE Office of Scientific and Technical Information (OSTI.GOV)

WYRWAS RB; PAGE JS; COOKE GS

This test plan describes the methods to be used in the forensic examination of the Multi-probe Corrosion Monitoring System (MPCMS) installed in the double-shell tank 241-AY-101 (AY-101). The probe was designed by Applied Research and Engineering Sciences (ARES) Corporation. The probe contains four sections, each of which can be removed from the tank independently (H-14-107634, AY-101 MPCMS Removable Probe Assembly) and one fixed center assembly. Each removable section contains three types of passive corrosion coupons: bar coupons, round coupons, and stressed C-rings (H-14-l07635, AY-101 MPCMS Details). Photographs and weights of each coupon were recorded and reported on drawing H-14-107634 andmore » in RPP-RPT-40629, 241-AY-101 MPCMS C-Ring Coupon Photographs. The coupons will be the subject of the forensic analyses. The purpose of this examination will be to document the nature and extent of corrosion of the 29 coupons. This documentation will consist of photographs and photomicrographs of the C-rings and round coupons, as well as the weights of the bar and round coupons during corrosion removal. The total weight loss of the cleaned coupons will be used in conjunction with the surface area of each to calculate corrosion rates in mils per year. The bar coupons were presumably placed to investigate the liquid-air-interface. An analysis of the waste level heights in the waste tank will be investigated as part of this examination.« less

Slurry growth, gas retention, and flammable gas generation by Hanford radioactive waste tanks: Synthetic waste studies, FY 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bryan, S.A.; Pederson, L.R.; Ryan, J.L.

1992-08-01

Of 177 high-level waste storage tanks on the Hanford Site, 23 have been placed on a safety watch list because they are suspected of producing flammable gases in flammable or explosive concentrate. One tankin particular, Tank 241-SY-101 (Tank 101-SY), has exhibited slow increases in waste volume followed by a rapid decrease accompanied by venting of large quantities of gases. The purpose of this study is to help determine the processes by which flammable gases are produced, retained, and eventually released from Tank 101-SY. Waste composition data for single- and double-shell waste tanks on the flammable gas watch listare critically reviewed.more » The results of laboratory studies using synthetic double-shell wastes are summarized, including physical and chemical properties of crusts that are formed, the stoichiometry and rate ofgas generation, and mechanisms responsible for formation of a floating crust.« less

Tank 241-AZ-101 criticality assessment resulting from pump jet mixing: Sludge mixing simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Onishi, Y.; Recknagle, K.

Tank 241-AZ-101 (AZ-101) is one of 28 double-shell tanks located in the AZ farm in the Hanford Site`s 200 East Area. The tank contains a significant quantity of fissile materials, including an estimated 9.782 kg of plutonium. Before beginning jet pump mixing for mitigative purposes, the operations must be evaluated to demonstrate that they will be subcritical under both normal and credible abnormal conditions. The main objective of this study was to address a concern about whether two 300-hp pumps with four rotating 18.3-m/s (60-ft/s) jets can concentrate plutonium in their pump housings during mixer pump operation and cause amore » criticality. The three-dimensional simulation was performed with the time-varying TEMPEST code to determine how much the pump jet mixing of Tank AZ-101 will concentrate plutonium in the pump housing. The AZ-101 model predicted that the total amount of plutonium within the pump housing peaks at 75 g at 10 simulation seconds and decreases to less than 10 g at four minutes. The plutonium concentration in the entire pump housing peaks at 0.60 g/L at 10 simulation seconds and is reduced to below 0.1 g/L after four minutes. Since the minimum critical concentration of plutonium is 2.6 g/L, and the minimum critical plutonium mass under idealized plutonium-water conditions is 520 g, these predicted maximums in the pump housing are much lower than the minimum plutonium conditions needed to reach a criticality level. The initial plutonium maximum of 1.88 g/L still results in safety factor of 4.3 in the pump housing during the pump jet mixing operation.« less

Chemical composition of Hanford Tank SY-102

DOE Office of Scientific and Technical Information (OSTI.GOV)

Birnbaum, E.; Agnew, S.; Jarvinen, G.

1993-12-01

The US Department of Energy established the Tank Waste Remediation System (TWRS) to safely manage and dispose of the radioactive waste, both current and future, stored in double-shell and single-shell tanks at the Hanford sites. One major program element in TWRS is pretreatment which was established to process the waste prior to disposal using the Hanford Waste Vitrification Plant. In support of this program, Los Alamos National Laboratory has developed a conceptual process flow sheet which will remediate the entire contents of a selected double-shelled underground waste tank, including supernatant and sludge, into forms that allow storage and final disposalmore » in a safe, cost-effective and environmentally sound manner. The specific tank selected for remediation is 241-SY-102 located in the 200 West Area. As part of the flow sheet development effort, the composition of the tank was defined and documented. This database was built by examining the history of liquid waste transfers to the tank and by performing careful analysis of all of the analytical data that have been gathered during the tank`s lifetime. In order to more completely understand the variances in analytical results, material and charge balances were done to help define the chemistry of the various components in the tank. This methodology of defining the tank composition and the final results are documented in this report.« less

Tank 241-AP-105, cores 208, 209 and 210, analytical results for the final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nuzum, J.L.

1997-10-24

This document is the final laboratory report for Tank 241-AP-105. Push mode core segments were removed from Risers 24 and 28 between July 2, 1997, and July 14, 1997. Segments were received and extruded at 222-S Laboratory. Analyses were performed in accordance with Tank 241-AP-105 Push Mode Core Sampling and Analysis Plan (TSAP) (Hu, 1997) and Tank Safety Screening Data Quality Objective (DQO) (Dukelow, et al., 1995). None of the subsamples submitted for total alpha activity (AT), differential scanning calorimetry (DSC) analysis, or total organic carbon (TOC) analysis exceeded the notification limits as stated in TSAP and DQO. The statisticalmore » results of the 95% confidence interval on the mean calculations are provided by the Tank Waste Remediation Systems Technical Basis Group, and are not considered in this report. Appearance and Sample Handling Two cores, each consisting of four segments, were expected from Tank 241-AP-105. Three cores were sampled, and complete cores were not obtained. TSAP states core samples should be transported to the laboratory within three calendar days from the time each segment is removed from the tank. This requirement was not met for all cores. Attachment 1 illustrates subsamples generated in the laboratory for analysis and identifies their sources. This reference also relates tank farm identification numbers to their corresponding 222-S Laboratory sample numbers.« less

Report on Electrochemcial Corrosion Testing of 241-SY-102 Grab Samples from the 2012 Grab Sampling Campaign

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wyrwas, Richard B.; Lamothe, Margaret E.

2013-05-30

This report describes the results of the electrochemical testing performed on tank 241-SY-102 (SY-102) grab samples that were collected in support of corrosion mitigation. The objective of the work presented here was to determine corrosion resistance of tank SY-102 to the grab samples collected using electrochemical methods up to 50°C as well as to satisfy data quality objectives. Grab samples were collected at multiple elevations from Riser 003. The electrochemical corrosion testing was planned to consist of linear polarization resistance testing (LPR) and cyclic potentiodynamic polarization (CPP) testing at 50°C. The temperature would be lowered to 40 °C and themore » test repeated if the CPP curve indicated pitting corrosion at 50°C. Ifno pitting was indicated by the CPP curve, then a duplicate scan would be repeated at 50°C to confirm the first result. The testing would be complete if the duplicate CPP scan was consistent with the first. This report contains the CPP results of the testing of grab sample 2SY-12-03 and 2SY-12-03DUP composite sample tested under these conditions. There was no indication of pitting at 50°C, and the duplicate scan was in agreement with the first scan. Since no further testing was required, a third scan with a shorter rest time was performed and is present in this report.« less

241-AW Tank Farm Construction Extent of Condition Review for Tank Integrity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnes, Travis J.; Gunter, Jason R.; Reeploeg, Gretchen E.

2013-11-19

This report provides the results of an extent of condition construction history review for the 241-AW tank farm. The construction history of the 241-AW tank farm has been reviewed to identify issues similar to those experienced during tank AY-102 construction. Those issues and others impacting integrity are discussed based on information found in available construction records, using tank AY-102 as the comparison benchmark. In the 241-AW tank farm, the fourth double-shell tank farm constructed, similar issues as those with tank 241-AY-102 construction occured. The overall extent of similary and affect on 241-AW tank farm integrity is described herein.

Radioactive air emissions notice of construction for installation and operation of a waste retrieval system and tanks 241-AP-102 and 241-AP-104 project

DOE Office of Scientific and Technical Information (OSTI.GOV)

DEXTER, M.L.

1999-11-15

This document serves as a notice of construction (NOC) pursuant to the requirements of Washington Administrative Code (WAC) 246 247-060, and as a request for approval to modify pursuant to 40 Code of Federal Regulations (CFR) 61 07 for the installation and operation of one waste retrieval system in the 24 1 AP-102 Tank and one waste retrieval system in the 241 AP 104 Tank Pursuant to 40 CFR 61 09 (a)( 1) this application is also intended to provide anticipated initial start up notification Its is requested that EPA approval of this application will also constitute EPA acceptance ofmore » the initial start up notification Project W 211 Initial Tank Retrieval Systems (ITRS) is scoped to install a waste retrieval system in the following double-shell tanks 241-AP 102-AP 104 AN 102, AN 103, AN-104, AN 105, AY 102 AZ 102 and SY-102 between now and the year 2011. Because of the extended installation schedules and unknowns about specific activities/designs at each tank, it was decided to submit NOCs as that information became available This NOC covers the installation and operation of a waste retrieval system in tanks 241 AP-102 and 241 AP 104 Generally this includes removal of existing equipment installation of new equipment and construction of new ancillary equipment and buildings Tanks 241 AP 102 and 241 AP 104 will provide waste feed for immobilization into a low activity waste (LAW) product (i.e. glass logs) The total effective dose equivalent (TEDE) to the offsite maximally exposed individual (MEI) from the construction activities is 0 045 millirem per year The unabated TEDE to the offsite ME1 from operation of the mixer pumps is 0 042 millirem per year.« less

241-AP Tank Farm Construction Extent of Condition Review for Tank Integrity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnes, Travis J.; Gunter, Jason R.; Reeploeg, Gretchen E.

2014-04-04

This report provides the results of an extent of condition construction history review for the 241-AP tank farm. The construction history of the 241-AP tank farm has been reviewed to identify issues similar to those experienced during tank AY-102 construction. Those issues and others impacting integrity are discussed based on information found in available construction records, using tank AY-102 as the comparison benchmark. In the 241-AP tank farm, the sixth double-shell tank farm constructed, tank bottom flatness, refractory material quality, post-weld stress relieving, and primary tank bottom weld rejection were improved.

Hanford Single-Shell Tank Leak Causes and Locations - 241-BY and 241-TY Farm

DOE Office of Scientific and Technical Information (OSTI.GOV)

Girardot, Crystal L.; Harlow, Donald G.

This document identifies 241-BY Tank Farm (BY Farm) and 241-TY Tank Farm (TY Farm) lead causes and locations for the 100 series leaking tanks (241-BY-103, 241-TY-103, 241-TY-104, 241-TY-105 and 241-TY-106) identified in RPP-RPT-43704, Hanford BY Farm Leak Assessments Report, and in RPP-RPT-42296, Hanford TY Farm Leak Assessments Report. This document satisfies the BY and TY Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

Tank 241-C-112 vapor sampling and analysis tank characterization report. Revision 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huckaby, J.L.

1995-05-31

Tank 241-C-112 headspace gas and vapor samples were collected and analyzed to help determine the potential risks to tank farm workers due to fugitive emissions from the tank. The drivers and objectives of waste tank headspace sampling and analysis are discussed in {open_quotes}Program Plan for the Resolution of Tank Vapor Issues.{close_quotes} Tank 241-C-112 was vapor sampled in accordance with {open_quotes}Data Quality Objectives for Generic In-Tank Health and Safety Issue Resolution.{close_quotes}

Tank characterization report for single-shell tank 241-C-109

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simpson, B.C.

1997-05-23

One of the major functions of the Tank Waste Remediation System (TWRS) is to characterize wastes in support of waste management and disposal activities at the Hanford Site. Analytical data from sampling and analysis, along with other available information about a tank, are compiled and maintained in a tank characterization report (TCR). This report and its appendices serve as the TCR for single-shell tank 241-C-109. The objectives of this report are: (1) to use characterization data in response to technical issues associated with tank 241 C-109 waste; and (2) to provide a standard characterization of this waste in terms ofmore » a best-basis inventory estimate. The response to technical issues is summarized in Section 2.0, and the best-basis inventory estimate is presented in Section 3.0. Recommendations regarding safety status and additional sampling needs are provided in Section 4.0. Supporting data and information are contained in the appendices.« less

241-AZ-101 Waste Tank Color Video Camera System Shop Acceptance Test Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

WERRY, S.M.

2000-03-23

This report includes shop acceptance test results. The test was performed prior to installation at tank AZ-101. Both the camera system and camera purge system were originally sought and procured as a part of initial waste retrieval project W-151.

Tank characterization report for double-shell tank 241-AW-105

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sasaki, L.M.

1997-06-05

One of the major functions of the Tank Waste Remediation System (TWRS) is to characterize wastes in support of waste management and disposal activities at the Hanford Site. Analytical data from sampling and analysis, along with other available information about a tank, are compiled and maintained in a tank characterization report (TCR). This report and its appendices serve as the TCR for double-shell tank 241-AW-105. The objectives of this report are to use characterization data in response to technical issues associated with tank 241-AW-105 waste; and to provide a standard characterization of this waste in terms of a best-basis inventorymore » estimate. The response to technical issues is summarized in Section 2.0, and the best-basis inventory estimate is presented in Section 3.0. Recommendations regarding safety status and additional sampling needs are provided in Section 4.0. Supporting data and information are contained in the appendices. This report supports the requirements of the Hanford Federal Facility Agreement and Consent Order milestone Characterization. information presented in this report originated from sample analyses and known historical sources. While only the results of a recent sampling event will be used to fulfill the requirements of the data quality objectives (DQOs), other information can be used to support or question conclusions derived from these results. Historical information for tank 241-AW-105 is provided in Appendix A, including surveillance information, records pertaining to waste transfers and tank operations, and expected tank contents derived from a process knowledge model. The recent sampling event listed, as well as pertinent sample data obtained before 1996, are summarized in Appendix B along with the sampling results. The results of the 1996 grab sampling event satisfied the data requirements specified in the sampling and analysis plan (SAP) for this tank. In addition, the tank headspace flammability was measured, which

Tank characterization report for single-shell tank 241-S-111

DOE Office of Scientific and Technical Information (OSTI.GOV)

Conner, J.M.

1997-04-28

One of the major functions of the Tank Waste Remediation System (TWRS) is to characterize wastes in support of waste management and disposal activities at the Hanford Site. Analytical data from sampling and analysis, along with other available information about a tank, are compiled and maintained in a tank characterization report (TCR). This report and its appendices serve as the TCR for single-shell tank 241-S-111. The objectives of this report are: (1) to use characterization data to address technical issues associated with tank 241-S-111 waste; and (2) to provide a standard characterization of this waste in terms of a best-basismore » inventory estimate. The response to technical issues is summarized in Section 2.0, and the best-basis inventory estimate is presented in Section 3.0. Recommendations regarding safety status and additional sampling needs are provided in Section 4.0. Supporting data and information are contained in the appendices. This report also supports the requirements of Hanford Federal Facility Agreement and Consent Order (Ecology et al. 1996) milestone M-44-10.« less

System configuration management plan for 101-SY Hydrogen Mitigation Test Project Mini-Data Acquisition and Control System of Tank Waste Remediation System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vargo, G.F. Jr.

1994-10-11

The DOE Standard defines the configuration management program by the five basic program elements of ``program management,`` ``design requirements,`` ``document control,`` ``change control,`` and ``assessments,`` and the two adjunct recovery programs of ``design reconstitution,`` and ``material condition and aging management. The C-M model of five elements and two adjunct programs strengthen the necessary technical and administrative control to establish and maintain a consistent technical relationship among the requirements, physical configuration, and documentation. Although the DOE Standard was originally developed for the operational phase of nuclear facilities, this plan has the flexibility to be adapted and applied to all life-cycle phasesmore » of both nuclear and non-nuclear facilities. The configuration management criteria presented in this plan endorses the DOE Standard and has been tailored specifically to address the technical relationship of requirements, physical configuration, and documentation during the full life-cycle of the 101-SY Hydrogen Mitigation Test Project Mini-Data Acquisition and Control System of Tank Waste Remediation System.« less

Hanford Single Shell Tank Leak Causes and Locations - 241-TX Farm

DOE Office of Scientific and Technical Information (OSTI.GOV)

Girardot, C. L.; Harlow, D> G.

This document identifies 241-TX Tank Farm (TX Farm) leak causes and locations for the 100 series leaking tanks (241-TX-107 and 241-TX-114) identified in RPP-RPT-50870, Rev. 0, Hanford 241-TX Farm Leak Inventory Assessment Report. This document satisfies the TX Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

49 CFR 179.101 - Individual specification requirements applicable to pressure tank car tanks.

Code of Federal Regulations, 2011 CFR

2011-10-01

... to pressure tank car tanks. 179.101 Section 179.101 Transportation Other Regulations Relating to... (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120) § 179.101 Individual specification requirements applicable to pressure tank car...

49 CFR 179.101 - Individual specification requirements applicable to pressure tank car tanks.

Code of Federal Regulations, 2013 CFR

2013-10-01

... to pressure tank car tanks. 179.101 Section 179.101 Transportation Other Regulations Relating to... (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120) § 179.101 Individual specification requirements applicable to pressure tank car...

49 CFR 179.101 - Individual specification requirements applicable to pressure tank car tanks.

Code of Federal Regulations, 2012 CFR

2012-10-01

... to pressure tank car tanks. 179.101 Section 179.101 Transportation Other Regulations Relating to... (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120) § 179.101 Individual specification requirements applicable to pressure tank car...

48 CFR 241.101 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Definitions. 241.101... Definitions. As used in this part— Independent regulatory body means the Federal Energy Regulatory Commission... Engineering Command; (3) Air Force, the head of a contracting activity; and (4) Defense Logistics Agency, the...

49 CFR 179.101 - Individual specification requirements applicable to pressure tank car tanks.

Code of Federal Regulations, 2010 CFR

2010-10-01

... to pressure tank car tanks. 179.101 Section 179.101 Transportation Other Regulations Relating to... MATERIALS REGULATIONS SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT... tank car tanks. Editorial Note: At 66 FR 45186, Aug. 28, 2001, an amendment published amending a table...

Tank characterization report for single-shell tank 241-U-110. Revision 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, T.M.; Jensen, L.

1993-09-01

Tank 241-U-110 (U-110) is a Hanford Site waste tank that was ;most recently sampled in November and December 1989. Analysis of the samples obtained from tank U-110 was conducted to support the characterization of the contents of this tank and to support Hanford Federal Facility Agreement and Consent Order milestone M-10-00 (Ecology, et al. 1992). Because of incomplete recovery of the waste during sampling, there may be bias in the results of this characterization report.

49 CFR 179.101 - Individual specification requirements applicable to pressure tank car tanks.

Code of Federal Regulations, 2014 CFR

2014-10-01

... to pressure tank car tanks. 179.101 Section 179.101 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109...

Final Report For The Erosion And Corrosion Analysis Of Waste Transfer Primary Pipeline Sections From 241-SY Tank Farm

DOE Office of Scientific and Technical Information (OSTI.GOV)

Page, J. S.; Wyrwas, R. B.; Cooke, G. A.

Three sections of primary transfer pipeline removed from the 241-SY Tank Farm in Hanford's 200 West area, labeled as SN-285, SN-286, and SN-278, were analyzed for the presence and amount of corrosion and erosion on the inside surface of the transfer pipe. All three sections of pipe, ranging in length between 6 and 8 in., were received at the 222-S Laboratory still in the pipe-in-pipe assembly. The annular spaces were filled with urethane foam injected into the pipes for as low as reasonably achievable (ALARA) purposes. The 3-in. primary transfer pipes were first separated from the outer encasement, 6-in. pipes.more » The pipes were cut into small sections, or coupons, based upon the results of a non-destructive pipe wall thickness measurement which used an ultrasonic transducer. Following removal of the foam, the coupons were subjected to a series of analytical methods utilizing both optical microscopy and scanning electron microscopy to obtain erosion and corrosion information. The ultrasonic transducer analysis of the SN-285 primary pipe did not show any thinned locations in the pipe wall which were outside the expected range for the 3-in. schedule 40 pipe of 216 mils. A coupon was cut from the thinnest area on the pipe, and analysis of the inside surface, which was in contact with the tank waste, revealed a continuous layer of corrosion ~ 100 11m (4 mils) thick under a semi-continuous layer of tank waste residue ~ 20 11m (1 mil) thick. This residue layer was composed of an amorphous phase rich in chromium, magnesium, calcium, and chlorine. Small pits were detected throughout the inside pipe surface with depths up to ~ 50 11m (2 mils). Similarly, the SN-286 primary pipe did not show, by the ultrasonic transducer measurements, any thinned locations in the pipe wall which were outside the expected range for this pipe. Analysis of the coupon cut from the pipe section showed the presence of a tank waste layer containing sodium aluminate and phases rich in iron

Chemical Characterization of an Envelope A Sample from Hanford Tank 241-AN-103

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hay, M.S.

2000-08-23

A whole tank composite sample from Hanford waste tank 241-AN-103 was received at the Savannah River Technology Center (SRTC) and chemically characterized. Prior to characterization the sample was diluted to {approximately}5 M sodium concentration. The filtered supernatant liquid, the total dried solids of the diluted sample, and the washed insoluble solids obtained from filtration of the diluted sample were analyzed. A mass balance calculation of the three fractions of the sample analyzed indicate the analytical results appear relatively self-consistent for major components of the sample. However, some inconsistency was observed between results where more than one method of determination wasmore » employed and for species present in low concentrations. A direct comparison to previous analyses of material from tank 241-AN-103 was not possible due to unavailability of data for diluted samples of tank 241-AN-103 whole tank composites. However, the analytical data for other types of samples from 241-AN-103 we re mathematically diluted and compare reasonably with the current results. Although the segments of the core samples used to prepare the sample received at SRTC were combined in an attempt to produce a whole tank composite, determination of how well the results of the current analysis represent the actual composition of the Hanford waste tank 241-AN-103 remains problematic due to the small sample size and the large size of the non-homogenized waste tank.« less

Vapor characterization of Tank 241-C-103

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huckaby, J.L.; Story, M.S.

The Westinghouse Hanford Company Tank Vapor Issue Resolution Program has developed, in cooperation with Northwest Instrument Systems, Inc., Oak Ridge National Laboratory, Oregon Graduate Institute of Science and Technology, Pacific Northwest Laboratory, and Sandia National Laboratory, the equipment and expertise to characterize gases and vapors in the high-level radioactive waste storage tanks at the Hanford Site in south central Washington State. This capability has been demonstrated by the characterization of the tank 241-C-103 headspace. This tank headspace is the first, and for many reasons is expected to be the most problematic, that will be characterized (Osborne 1992). Results from themore » most recent and comprehensive sampling event, sample job 7B, are presented for the purpose of providing scientific bases for resolution of vapor issues associated with tank 241-C-103. This report is based on the work of Clauss et al. 1994, Jenkins et al. 1994, Ligotke et al. 1994, Mahon et al. 1994, and Rasmussen and Einfeld 1994. No attempt has been made in this report to evaluate the implications of the data presented, such as the potential impact of headspace gases and vapors to tank farm workers health. That and other issues will be addressed elsewhere. Key to the resolution of worker health issues is the quantitation of compounds of toxicological concern. The Toxicology Review Panel, a panel of Pacific Northwest Laboratory experts in various areas, of toxicology, has chosen 19 previously identified compounds as being of potential toxicological concern. During sample job 7B, the sampling and analytical methodology was validated for this preliminary list of compounds of toxicological concern. Validation was performed according to guidance provided by the Tank Vapor Conference Committee, a group of analytical chemists from academic institutions and national laboratories assembled and commissioned by the Tank Vapor Issue Resolution Program.« less

Tank 241-Z-361 Sludge Retrieval and Treatment Alternatives

DOE Office of Scientific and Technical Information (OSTI.GOV)

HAMPTON, B.K.

2000-05-24

The Plutonium Finishing Plant (PFP) Tank 241-Z-361 (Z-361) contains legacy sludge resulting from waste discharges from past missions at PFP. A sketch of the tank is shown in Figure 1. In this view various risers and penetrations are shown along with the sludge level depicted by the horizontal line halfway up the tank, and the ground level depicted by the horizontal line above the tank. The HEPA filter installed for breathing is also shown on one of the risers.

241-AY Double Shell Tanks (DST) Integrity Assessment Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

JENSEN, C.E.

1999-09-21

This report presents the results of the integrity assessment of the 241-AY double-shell tank farm facility located in the 200 East Area of the Hanford Site. The assessment included the design evaluation and integrity examinations of the tanks and concluded that the facility is adequately designed, is compatible with the waste, and is fit for use. Recommendations including subsequent examinations. are made to ensure the continued safe operation of the tanks.

Hanford Tanks 241-C-203 and 241-C-204: Residual Waste Contaminant Release Model and Supporting Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deutsch, William J.; Krupka, Kenneth M.; Lindberg, Michael J.

This report describes the development of release models for key contaminants that are present in residual sludge remaining after closure of Hanford Tanks 241-C-203 (C-203) and 241-C-204 (C-204). The release models were developed from data generated by laboratory characterization and testing of samples from these two tanks. Key results from this work are (1) future releases from the tanks of the primary contaminants of concern (99Tc and 238U) can be represented by relatively simple solubility relationships between infiltrating water and solid phases containing the contaminants; and (2) high percentages of technetium-99 in the sludges (20 wt% in C-203 and 75more » wt% in C-204) are not readily water leachable, and, in fact, are very recalcitrant. This is similar to results found in related studies of sludges from Tank AY-102. These release models are being developed to support the tank closure risk assessments performed by CH2M HILL Hanford Group, Inc., for the U.S. Department of Energy.« less

241-AZ Farm Annulus Extent of Condition Baseline Inspection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Engeman, Jason K.; Girardot, Crystal L.; Vazquez, Brandon J.

2013-05-15

This report provides the results of the comprehensive annulus visual inspection for tanks 241- AZ-101 and 241-AZ-102 performed in fiscal year 2013. The inspection established a baseline covering about 95 percent of the annulus floor for comparison with future inspections. Any changes in the condition are also included in this document.

Project W-211, initial tank retrieval systems, description of operations for 241-AP-102 and 241-AP-104

DOE Office of Scientific and Technical Information (OSTI.GOV)

RIECK, C.A.

1999-02-25

The primary purpose of the Initial Tank Retrieval Systems (ITRS) is to provide systems for retrieval of radioactive wastes stored in underground double-shell tanks (DSTS) for transfer to alternate storage, evaporation, pretreatment or treatment, while concurrently reducing risks associated with safety watch list and other DSTs. This Description of Operations (DOO) defines the control philosophy for the waste retrieval system for tanks 241-AP-102 (AP-102) and 241-AP-104 (AP-104). This DOO will provide a basis for the detailed design of the Retrieval Control System (RCS) for AP-102 and AP-104 and establishes test criteria for the RCS. The test criteria will be usedmore » during qualification testing and acceptance testing to verify operability.« less

Dangerous Waste Characteristics of Waste from Hanford Tank 241-S-109

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tingey, Joel M.; Bryan, Garry H.; Deschane, Jaquetta R.

2004-11-05

Existing analytical data from samples taken from Hanford Tank 241-S-109, along with process knowledge of the wastes transferred to this tank, are reviewed to determine whether dangerous waste characteristics currently assigned to all waste in Hanford underground storage tanks are applicable to this tank waste. Supplemental technologies are examined to accelerate the Hanford tank waste cleanup mission and to accomplish the waste treatment in a safer and more efficient manner. The goals of supplemental technologies are to reduce costs, conserve double-shell tank space, and meet the scheduled tank waste processing completion date of 2028.

Test Report for Permanganate and Cold Strontium Strike for Tank 241-AN-102

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duncan, James B.; Huber, Heinz J.; Smalley, Colleen S.

Tanks 241-AN-102 and 241-AN-107 supernatants contain soluble Sr-90 and transuranic elements that require removal prior to vitrification to comply with the Waste Treatment and Immobilization Plant immobilized low-activity waste specification (WTP Contract, DE-AC27-01RV 14136, Specification 2.2.2.8, "Radionuclide Concentration Limitations") and the U.S. Nuclear Regulatory Commission provisional agreement on waste incidental to reprocessing (letter, Paperiello, C. J., "Classification of Hanford Low-Activity Tank Waste Fraction"). These two tanks have high concentrations of organics and organic complexants and are referred to as complexant concentrate tanks. A precipitation process using sodium permanganate (NaMnO{sub 4}) and strontium nitrate (Sr(NO{sub 3}){sub 2}) was developed and testedmore » with tank waste samples to precipitate Sr-90 and transuranic elements from the supernate (PNWD-3141, Optimization of Sr/TRU Removal Conditions with Samples of AN-102 Tank Waste). Testing documented in this report was conducted to further evaluate the use of the strontium nitrate/sodium permanganate process in tank farms with a retention time of up to 12 months. Previous testing was focused on developing a process for deployment in the ultrafiltration vessels in the Waste Treatment and Immobilization Plant. This environment is different from tank farms in two important ways: the waste is diluted in the Waste Treatment and Immobilization Plant to ~5.5 M sodium, whereas the supernate in the tank farms is ~9 M Na. Secondly, while the Waste Treatment and Immobilization Plant allows for a maximum treatment time of hours to days, the in-tank farms treatment of tanks 241-AN102 and 241-AN-107 will result in a retention time of months (perhaps up to12 months) before processing. A comparative compilation of separation processes for Sr/transuranics has been published as RPP-RPT-48340, Evaluation of Alternative Strontium and Transuranic Separation Processes. This report also listed the

Toxicologic evaluation of analytes from Tank 241-C-103

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mahlum, D.D.; Young, J.Y.; Weller, R.E.

1994-11-01

Westinghouse Hanford Company requested PNL to assemble a toxicology review panel (TRP) to evaluate analytical data compiled by WHC, and provide advice concerning potential health effects associated with exposure to tank-vapor constituents. The team`s objectives would be to (1) review procedures used for sampling vapors from tanks, (2) identify constituents in tank-vapor samples that could be related to symptoms reported by workers, (3) evaluate the toxicological implications of those constituents by comparison to establish toxicological databases, (4) provide advice for additional analytical efforts, and (5) support other activities as requested by WHC. The TRP represents a wide range of expertise,more » including toxicology, industrial hygiene, and occupational medicine. The TRP prepared a list of target analytes that chemists at the Oregon Graduate Institute/Sandia (OGI), Oak Ridge National Laboratory (ORNL), and PNL used to establish validated methods for quantitative analysis of head-space vapors from Tank 241-C-103. this list was used by the analytical laboratories to develop appropriate analytical methods for samples from Tank 241-C-103. Target compounds on the list included acetone, acetonitrile, ammonia, benzene, 1, 3-butadiene, butanal, n-butanol, hexane, 2-hexanone, methylene chloride, nitric oxide, nitrogen dioxide, nitrous oxide, dodecane, tridecane, propane nitrile, sulfur oxide, tributyl phosphate, and vinylidene chloride. The TRP considered constituent concentrations, current exposure limits, reliability of data relative to toxicity, consistency of the analytical data, and whether the material was carcinogenic or teratogenic. A final consideration in the analyte selection process was to include representative chemicals for each class of compounds found.« less

New rain shed (Building No. 241) on right with Tanks ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

New rain shed (Building No. 241) on right with Tanks T5, T4 and T2 on left from front to back. - Hawaii Volcanoes National Park Water Collection System, Hawaii Volcanoes National Park, Volcano, Hawaii County, HI

Hanford Tanks 241-C-203 and 241 C 204: Residual Waste Contaminant Release Model and Supporting Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deutsch, William J.; Krupka, Kenneth M.; Lindberg, Michael J.

This report was revised in May 2007 to correct 90Sr values in Chapter 3. The changes were made on page 3.9, paragraph two and Table 3.10; page 3.16, last paragraph on the page; and Tables 3.21 and 3.31. The rest of the text remains unchanged from the original report issued in October 2004. This report describes the development of release models for key contaminants that are present in residual sludge remaining after closure of Hanford Tanks 241-C-203 (C-203) and 241-C-204 (C-204). The release models were developed from data generated by laboratory characterization and testing of samples from these two tanks.more » Key results from this work are (1) future releases from the tanks of the primary contaminants of concern (99Tc and 238U) can be represented by relatively simple solubility relationships between infiltrating water and solid phases containing the contaminants; and (2) high percentages of technetium-99 in the sludges (20 wt% in C-203 and 75 wt% in C-204) are not readily water leachable, and, in fact, are very recalcitrant. This is similar to results found in related studies of sludges from Tank AY-102. These release models are being developed to support the tank closure risk assessments performed by CH2M HILL Hanford Group, Inc., for the U.S. Department of Energy.« less

Solid Phase Characterization of Tank 241-C-105 Grab Samples

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ely, T. M.; LaMothe, M. E.; Lachut, J. S.

The solid phase characterization (SPC) of three grab samples from single-shell Tank 241-C-105 (C-105) that were received at the laboratory the week of October 26, 2015, has been completed. The three samples were received and broken down in the 11A hot cells.

ESP`s Tank 42 washwater transfer to the 241-F/H tank farms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aponte, C.I.; Lee, E.D.

1997-12-01

As a result of the separation of the High-Level Liquid Waste Department into three separate organizations (formerly there were two) (Concentration, Storage, and Transfer (CST), Waste Pre-Treatment (WPT) and Waste Disposition (WD)) process interface controls were required. One of these controls is implementing the Waste the waste between CST and WPT. At present, CST`s Waste Acceptance Criteria is undergoing revision and WPT has not prepared the required Waste Compliance Plan (WCP). The Waste Pre-Treatment organization is making preparations for transferring spent washwater in Tank 42 to Tank 43 and/or Tank 22. The washwater transfer is expected to complete the washingmore » steps for preparing ESP batch 1B sludge. This report is intended to perform the function of a Waste Compliance Plan for the proposed transfer. Previously, transfers between the Tank Farm and ITP/ESP were controlled by requirements outlined in the Tank Farm`s Technical Standards and ITP/ESP`s Process Requirements. Additionally, these controls are implemented primarily in operating procedure 241-FH-7TSQ and ITP Operations Manual SW16.1-SOP-WTS-1 which will be completed prior to performing the waste transfers.« less

Small Column Ion Exchange Testing of Superlig 644 for Removal of 137Cs from Hanford Tank Waste Envelope A (Tank 241-AW-101)

DOE Office of Scientific and Technical Information (OSTI.GOV)

DE Kurath; DL Blanchard; JR Bontha

The current BNFL Inc. flow sheet for the pretreatment of the Hanford High-Level tank wastes includes the use of Superlig{reg_sign} materials for the removal of {sup 137}Cs from the aqueous fraction of the waste. The Superlig materials applicable to cesium removal include the cesium selective Superlig 632 and Superlig 644. These materials have been developed and supplied by IBC Advanced Technologies, Inc., American Fork, UT. The work contained in this report involves testing the Superlig 644 ion exchange material in a small dual column system (15 mL each; L/D = 5.7). The sample processed was approximately 2.5 L of dilutedmore » waste [Na{sup +}] = 4.6M from Tank 241-AW-101 (Envelope A). This waste had been previously clarified in a single tube cross-flow filtration unit. All ion exchange process steps were tested including resin bed preparation, loading, feed displacement water rinse, elution and resin regeneration. During the initial run, the lag column did not perform as expected so that the {sup 137}Cs concentration in the effluent composite was above the LAW treatment limits. This required a second column run with the partially decontaminated feed that was conducted at a higher flow rate. A summary of performance measures for both runs is shown in Table S1. The Cs {lambda} values represent a measure of the effective capacity of the SL-644 resin. The Cs {lambda} of 143 for the lead column in run 1 is very similar to the value obtained by the Savannah River Technology Center during Phase 1A testing. The larger Cs {lambda} value for run 2 reflects a general trend for the effective capacity of the SL-644 material to increase as the cesium concentration decreases. The low value for the lag column during the first run indicates that it did not perform as expected. This may have been due to insufficient conditioning of the bed prior to the start of the loading step or to air in the bed that caused channeling. Equilibrium data obtained with batch contacts using the AW

Evaluation of 241-AZ tank farm supporting phase 1 privatization waste feed delivery

DOE Office of Scientific and Technical Information (OSTI.GOV)

CARLSON, A.B.

1998-11-19

This evaluation is one in a series of evaluations determining the process needs and assessing the adequacy of existing and planned equipment in meeting those needs at various double-shell tank farms in support of Phase 1 privatization. A number of tank-to-tank transfers and waste preparation activities are needed to process and feed waste to the private contractor in support of Phase 1 privatization. The scope of this evaluation is limited to process needs associated with 241-AZ tank farm during the Phase 1 privatization.

A summary description of the flammable gas tank safety program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, G.D.; Sherwood, D.J.

1994-10-01

Radioactive liquid waste may produce hydrogen as result of the interaction of gamma radiation and water. If the waste contains organic chelating agents, additional hydrogen as well as nitrous oxide and ammonia may be produced by thermal and radiolytic decomposition of these organics. Several high-level radioactive liquid waste storage tanks, located underground at the Hanford Site in Washington State, are on a Flammable Gas Watch List. Some contain waste that produces and retains gases until large quantities of gas are released rapidly to the tank vapor space. Tanks nearly-filled to capacity have relatively little vapor space; therefore if the wastemore » suddenly releases a large amount of hydrogen and nitrous oxide, a flammable gas mixture could result. The most notable example of a Hanford waste tank with a flammable gas problem is tank 241-SY-101. Upon occasion waste stored in this tank has released enough flammable gas to burn if an ignition source had been present inside of the tank. Several, other Hanford waste tanks exhibit similar behavior although to a lesser magnitude. Because this behavior was hot adequately-addressed in safety analysis reports for the Hanford Tank Farms, an unreviewed safety question was declared, and in 1990 the Flammable Gas Tank Safety Program was established to address this problem. The purposes of the program are a follows: (1) Provide safety documents to fill gaps in the safety analysis reports, and (2) Resolve the safety issue by acquiring knowledge about gas retention and release from radioactive liquid waste and developing mitigation technology. This document provides the general logic and work activities required to resolve the unreviewed safety question and the safety issue of flammable gas mixtures in radioactive liquid waste storage tanks.« less

Evaluation of Hanford Single-Shell Waste Tanks Suspected of Water Intrusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feero, Amie J.; Washenfelder, Dennis J.; Johnson, Jeremy M.

2013-11-14

Intrusions evaluations for twelve single-shell tanks were completed in 2013. The evaluations consisted of remote visual inspections, data analysis, and calculations of estimated intrusion rates. The observation of an intrusion or the preponderance of evidence confirmed that six of the twelve tanks evaluated had intrusions. These tanks were tanks 241-A-103, BX-101, BX-103, BX-110, BY-102, and SX-106.

Tank 241-AX-104 upper vadose zone cone penetrometer demonstration sampling and analysis plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

FIELD, J.G.

1999-02-02

This sampling and analysis plan (SAP) is the primary document describing field and laboratory activities and requirements for the tank 241-AX-104 upper vadose zone cone penetrometer (CP) demonstration. It is written in accordance with Hanford Tank Initiative Tank 241-AX-104 Upper Vadose Zone Demonstration Data Quality Objective (Banning 1999). This technology demonstration, to be conducted at tank 241-AX-104, is being performed by the Hanford Tanks Initiative (HTI) Project as a part of Tank Waste Remediation System (TWRS) Retrieval Program (EM-30) and the Office of Science and Technology (EM-50) Tanks Focus Area. Sample results obtained as part of this demonstration will providemore » additional information for subsequent revisions to the Retrieval Performance Evaluation (RPE) report (Jacobs 1998). The RPE Report is the result of an evaluation of a single tank farm (AX Tank Farm) used as the basis for demonstrating a methodology for developing the data and analyses necessary to support making tank waste retrieval decisions within the context of tank farm closure requirements. The RPE includes a study of vadose zone contaminant transport mechanisms, including analysis of projected tank leak characteristics, hydrogeologic characteristics of tank farm soils, and the observed distribution of contaminants in the vadose zone in the tank farms. With limited characterization information available, large uncertainties exist as to the nature and extent of contaminants that may exist in the upper vadose zone in the AX Tank Farm. Traditionally, data has been collected from soils in the vadose zone through the installation of boreholes and wells. Soil samples are collected as the bore hole is advanced and samples are screened on site and/or sent to a laboratory for analysis. Some in-situ geophysical methods of contaminant analysis can be used to evaluate radionuclide levels in the soils adjacent to an existing borehole. However, geophysical methods require compensation for

Safety evaluation for packaging transportation of equipment for tank 241-C-106 waste sluicing system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Calmus, D.B.

1994-08-25

A Waste Sluicing System (WSS) is scheduled for installation in nd waste storage tank 241-C-106 (106-C). The WSS will transfer high rating sludge from single shell tank 106-C to double shell waste tank 241-AY-102 (102-AY). Prior to installation of the WSS, a heel pump and a transfer pump will be removed from tank 106-C and an agitator pump will be removed from tank 102-AY. Special flexible receivers will be used to contain the pumps during removal from the tanks. After equipment removal, the flexible receivers will be placed in separate containers (packagings). The packaging and contents (packages) will be transferredmore » from the Tank Farms to the Central Waste Complex (CWC) for interim storage and then to T Plant for evaluation and processing for final disposition. Two sizes of packagings will be provided for transferring the equipment from the Tank Farms to the interim storage facility. The packagings will be designated as the WSSP-1 and WSSP-2 packagings throughout the remainder of this Safety Evaluation for Packaging (SEP). The WSSP-1 packagings will transport the heel and transfer pumps from 106-C and the WSSP-2 packaging will transport the agitator pump from 102-AY. The WSSP-1 and WSSP-2 packagings are similar except for the length.« less

Riser Difference Uncertainty Methodology Based on Tank AY-101 Wall Thickness Measurements with Application to Tank AN-107

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weier, Dennis R.; Anderson, Kevin K.; Berman, Herbert S.

2005-03-10

The DST Integrity Plan (RPP-7574, 2003, Double-Shell Tank Integrity Program Plan, Rev. 1A, CH2M HILL Hanford Group, Inc., Richland, Washington.) requires the ultrasonic wall thickness measurement of two vertical scans of the tank primary wall while using a single riser location. The resulting measurements are then used in extreme value methodology to predict the minimum wall thickness expected for the entire tank. The representativeness of using a single riser in this manner to draw conclusions about the entire circumference of a tank has been questioned. The only data available with which to address the representativeness question comes from Tank AY-101more » since only for that tank have multiple risers been used for such inspection. The purpose of this report is to (1) further characterize AY-101 riser differences (relative to prior work); (2) propose a methodology for incorporating a ''riser difference'' uncertainty for subsequent tanks for which only a single riser is used, and (3) specifically apply the methodology to measurements made from a single riser in Tank AN-107.« less

Investigation of Tank 241-AW-104 Composite Floating Layer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meznarich, H. K.; Bolling, S. D.; Lachut, J. S.

Seven grab samples and one field blank were taken from Tank 241-AW-104 (AW-104) on June 2, 2017, and received at 222-S Laboratory on June 5, 2017. A visible layer with brown solids was observed floating on the top of two surface tank waste samples (4AW-17-02 and 4AW 17 02DUP). The floating layer from both samples was collected, composited, and submitted for chemical analyses and solid phase characterization in order to understand the composition of the floating layer. Tributyl phosphate and tridecane were higher in the floating layer than in the aqueous phase. Density in the floating layer was slightly lowermore » than the mean density of all grab samples. Sodium nitrate and sodium carbonate were major components with a trace of gibbsite and very small size agglomerates were present in the solids of the floating layer. The supernate consisted of organics, soluble salt, and particulates.« less

Tank 241-AP-103 08/1999 Compatibility Grab Samples and Analytical Results for the Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

BELL, K.E.

1999-12-09

This document is the format IV, final report for the tank 241-AP-103 (AP-103) grab samples taken in August 1999 to address waste compatibility concerns. Chemical, radiochemical, and physical analyses on the tank AP-103 samples were performed as directed in ''Compatibility Grub Sampling and Analysis Plan for Fiscal Year 1999'' (Sasaki 1999a). Any deviations from the instructions provided in the tank sampling and analysis plan (TSAP) were discussed in this narrative. No notification limits were exceeded.

Tank 241-AY-102 Leak Assessment Supporting Documentation: Miscellaneous Reports, Letters, Memoranda, And Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Engeman, J. K.; Girardot, C. L.; Harlow, D. G.

2012-12-20

This report contains reference materials cited in RPP-ASMT -53793, Tank 241-AY-102 Leak Assessment Report, that were obtained from the National Archives Federal Records Repository in Seattle, Washington, or from other sources including the Hanford Site's Integrated Data Management System database (IDMS).

Project W-211 Initial Tank Retrieval Systems (ITRS) Description of Operations for 241-AZ-102

DOE Office of Scientific and Technical Information (OSTI.GOV)

BRIGGS, S.R.

2000-02-25

The primary purpose of the Initial Tank Retrieval Systems (ITRS) is to provide systems for retrieval of radioactive wastes stored in underground double-shell tanks (DSTs) for transfer to alternate storage, evaporation, pretreatment or treatment, while concurrently reducing risks associated with safety watch list and other DSTs. This Description of Operation (DOO) defines the control philosophy for the waste retrieval system for Tank 241-AZ-102 (AZ-102). This DOO provides a basis for the detailed design of the Project W-211 Retrieval Control System (RCS) for AZ-102 and also establishes test criteria for the RCS.

Chemical Characterization of an Envelope B/D Sample from Hanford Tank 241-AZ-102

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hay, M.S.

2000-08-23

A sample from Hanford waste tank 241-AZ-102 was received at the Savannah River Technology Center (SRTC) and chemically characterized. The sample containing supernate and a small amount of sludge solids was analyzed as-received. The filtered supernatant liquid, the total dried solids of the sample, and the washed insoluble solids obtained from filtration of the sample were analyzed. A mass balance calculation of the three fractions of the sample analyzed indicate the analytical results appear relatively self-consistent for major components of the sample. However, some inconsistency was observed between results were more than one method of determination was employed and formore » species present in low concentrations. The actinides isotopes, plutonium, americium, and curium, present analytical challenges due to the low concentration of these species and the potential for introduction of small amounts of contamination during sampling handling resulting in large uncertainties. A direct comparison to previous analyses of material from tank 241-AZ-102 showed good agreement with the filtered supernatant liquid. However, the comparison of solids data showed poor agreement. The poor agreement shown between the current results for the solids samples and previous analyses most likely results from the uncertainties associated with obtaining small solids samples from a large non-homogenized waste tank.« less

Tank 241-AY-102 Secondary Liner Corrosion Evaluation - 14191

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boomer, Kayle D.; Washenfelder, Dennis J.; Johnson, Jeremy M.

2014-01-07

In October 2012, Washington River Protection Solutions, LLC (WRPS) determined that the primary tank of 241-AY-102 (AY-102) was leaking. A number of evaluations were performed after discovery of the leak which identified corrosion from storage of waste at the high waste temperatures as one of the major contributing factors in the failure of the tank. The propensity for corrosion of the waste on the annulus floor will be investigated to determine if it is corrosive and must be promptly removed or if it is benign and may remain in the annulus. The chemical composition of waste, the temperature and themore » character of the steel are important factors in assessing the propensity for corrosion. Unfortunately, the temperatures of the wastes in contact with the secondary steel liner are not known; they are estimated to range from 45 deg C to 60 deg C. It is also notable that most corrosion tests have been carried out with un-welded, stress-relieved steels, but the secondary liner in tank AY-102 was not stress-relieved. In addition, the cold weather fabrication and welding led to many problems, which required repeated softening of the metal to flatten secondary bottom during its construction. This flame treatment may have altered the microstructure of the steel.« less

Discovery of the First Leaking Double-Shell Tank - Hanford Tank 241-AY-102

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harrington, Stephanie J.; Sams, Terry L.

Full text - Long Abstract. A routine video inspection of the annulus region of double-shell tank 241-A Y-102 in August of 2012 indicated the presence material in the annulus space between the primary and secondary liners. A comparison was made to previous inspections performed in 2006 and 2007. which indicated that a change had occurred. The material was observed at two locations on the floor of the annulus and one location at the top of the annulus region where the primary and secondary top knuckles meet (RPP-ASMT-53793). Subsequent inspections were performed. leading to additional material observed on the floor ofmore » the annulus space in a region that had not previously been inspected (WRPS-PER-2012-1363). The annulus Continuous Air Monitor (CAM) was still operational and was not indicating elevated radiation levels in the annulus region. When the camera from the inspections was recovered. it also did not indicate increased radiation above minimum contamination levels (WRPS-PER-2012-1363). A formal leak assessment team was established August 10, 2012 to review tank 241-AY-102 construction and operating histories and to determine whether the material observed in the annulus had resulted from a leak in the primary tank. The team consisted of individuals from Engineering. Base Operations and Environmental Protection. As this was a first-of-its-kind task. a method for obtaining a sample of the material in the annulus was needed. The consistency of the material was unknown.and the location of a majority of the material was not conducive to using the sampling devices that were currently available at Hanford. A subcontractor was tasked with the development fabrication.and testing of a sampling device that would be able to obtain multiple samples from the material on the annulus floor. as well as the material originating from a refractory air-slot near the floor of the annulus space. This sampler would need to be able to collect and dispense the material it

Test Report for Cesium and Solids Removal from an 11.5L Composite of Archived Hanford Double Shell Tank Supernate for Off-Site Disposal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doll, Stephanie R.; Cooke, Gary A.

The 222-S Laboratory blended supernate waste from Hanford Tanks 241-AN-101, 241-AN- 106, 241-AP-105, 241-AP-106, 241-AP-107, and 241-AY-101 from the hot cell archive to create a bulk composite. The composite was blended with 600 mL 19.4 M NaOH, which brought the total volume to approximately 11.5 L (3 gal). The composite was filtered to remove solids and passed through spherical resorcinol-formaldehyde ion-exchange resin columns to remove cesium. The composite masses were tracked as a treatability study. Samples collected before, during, and after the ion-exchange process were characterized for a full suite of analytes (inorganic, organic, and radionuclides) to aid in themore » classification of the waste for shipping, receiving, treatment, and disposal determinations.« less

Test Report for Cesium and Solids Removal from an 11.5L Composite of Archived Hanford Double Shell Tank Supernate for Off-Site Disposal.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doll, S. R.; Cooke, G. A.

The 222-S Laboratory blended supernate waste from Hanford Tanks 241-AN-101, 241-AN- 106, 241-AP-105, 241-AP-106, 241-AP-107, and 241-AY-101 from the hot cell archive to create a bulk composite. The composite was blended with 600 mL 19.4 M NaOH, which brought the total volume to approximately 11.5 L (3 gal). The composite was filtered to remove solids and passed through spherical resorcinol-formaldehyde ion-exchange resin columns to remove cesium. The composite masses were tracked as a treatability study. Samples collected before, during, and after the ion exchange process were characterized for a full suite of analytes (inorganic, organic, and radionuclides) to aid inmore » the classification of the waste for shipping, receiving, treatment, and disposal determinations.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stewart, Charles W.

Radioactive waste tank SY-101 is one of 177 big underground tanks that store waste from decades of plutonium production at the Hanford Nuclear Reservation in central Washington State. The chemical reactions and radioactivity in all the tanks make bubbles of flammable gas, mainly hydrogen along with a little methane and ammonia. But SY-101 was the most potent gas producer of all. Every few months the gas built up in the million gallons of extra-thick slurry until it suddenly came up in great rushing ''burps''. A few of the tank's larger burps let off enough gas to make the air spacemore » at the top of the tank flammable for a few hours. This flammable gas hazard became a dominating force in DOE nuclear waste management politics in the last two decades of the 20th century. It demanded the toil of scientists, managers, and officials from the time it was filled in 1980, until it was finally declared safe in January 2001. The tank seemed almost a personality--acting with violence and apparent malice, hiding information about itself, deceiving us with false indications, and sometimes lulling us into complacency only to attack in a new way. From 1990 through 1993, SY-101's flammable gas troubles were acknowledged as the highest priority safety issue in the entire DOE complex. Uncontrolled crust growth demanded another high-priority remedial effort from 1998 through April 2000. The direct cost of the bubbles, toils, and troubles was high. Overall, the price of dealing with the real and imagined hazards in SY-101 may have reached $250 million. The indirect cost was also high. Spending all this money fighting SY-101?s safety issues only stirred radioactive waste up and moved it around, but accomplished no cleanup whatever. Worse yet, the flammable gas problem spawned suspicions of a much wider danger that impeded and complicated cleanup in other 176 waste tanks for a decade. The real cleanup job has yet to be done. The SY-101 story is really about the collective

Headspace vapor characterization of Hanford Waste Tank 241-BY-108: Results from samples collected January 23, 1996. Tank Vapor Characterization Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pool, K.H.; Evans, J.C.; Thomas, B.L.

1996-07-01

This report describes the results of vapor samples obtained to compare vapor sampling of the tank headspace using the Vapor Sampling System (VSS) and In Situ Vapor Sampling System (ISVS) with and without particulate prefiltration. Samples were collected from the headspace of waste storage tank 241-BY-108 (Tank BY-108) at the Hanford Site in Washington State. Pacific Northwest National Laboratory (PNNL) was contracted by Westinghouse Hanford Company (WHC) to provide sampling devices and analyze samples for water, ammonia, permanent gases, total nonmethane hydrocarbons (TNMHCs, also known as TO-12), and organic analytes in samples collected in SUMMA{trademark} canisters and on triple sorbentmore » traps (TSTs) from the tank headspace. The analytical work was performed by the PNNL Vapor Analytical Laboratory (VAL) by the Tank Vapor Characterization Project. Work performed was based on a sampling and analysis plan (SAP) prepared by WHC. The SAP provided job-specific instructions for samples, analyses, and reporting. The SAP for this sample job was {open_quotes}Sampling and Analysis Plan for Tank Vapor Sampling Comparison Test{close_quotes}, and the sample jobs were designated S6004, S6005, and S6006. Samples were collected by WHC on January 23, 1996, using the VSS, a truck-based sampling method using a heated probe; and the ISVS with and without particulate prefiltration.« less

Final Report of Tank 241-C-105 Dissolution, the Phase 2 Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meznarich, Huei K.; bolling, Stacey D.; Cooke, Gary A.

2016-10-01

Three clamshell grab samples were taken from Tank 241-C-105 in October 2015 in accordance with RPP-PLAN-60011. Analytical results of those samples were issued in the report RPP-RPT-59115 by Wastren Advantage, Inc., Hanford Laboratory. Solid phase characterization results were reported separately in LAB-RPT-15-00011 and in RPP-RPT-59147. The major solid phases reported to be present were dawsonite [NaAlCO 3(OH) 2], trona [Na 3(HCO 3)(CO 3)·2H 2O], cejkaite [Na 4(UO 2)(CO 3) 3], and an unidentified organic solid, with minor amounts of gibbsite [Al(OH) 3], natrophosphate [Na 7F(PO 4) 2·19H 2O], and traces of unidentified iron-rich and manganese-rich phases. Note that the presencemore » of dawsonite, trona, and cejkaite requires a relatively low pH, likely around pH 9 to 10. One aliquot of each grab sample was provided to 222-S Laboratory Process Chemistry for dissolution studies. Phase 1 of the dissolution testing followed the approved test plan, WRPS-1404813, Rev. 3, and examined the behavior of the Tank 241-C-105 solids treated with water, 19M sodium hydroxide, 2M nitric acid, and 0.5M oxalic acid/2M nitric acid. Phase 2 of the testing was conducted in accordance with instructions from the client and emphasized treatment with 19M sodium hydroxide followed by water washing. This is the report of the Phase 2 testing.« less

Tank Vapor Sampling and Analysis Data Package for Tank 241-Z-361 Sampled 09/22/1999 and 09/271999 During Sludge Core Removal

DOE Office of Scientific and Technical Information (OSTI.GOV)

VISWANATH, R.S.

This data package presents sampling data and analytical results from the September 22 and 27, 1999, headspace vapor sampling of Hanford Site Tank 241-2-361 during sludge core removal. The Lockheed Martin Hanford Corporation (LMHC) sampling team collected the samples and Waste Management Laboratory (WML) analyzed the samples in accordance with the requirements specified in the 241-2361 Sludge Characterization Sampling and Analysis Plan, (SAP), HNF-4371, Rev. 1, (Babcock and Wilcox Hanford Corporation, 1999). Six SUMMA{trademark} canister samples were collected on each day (1 ambient field blank and 5 tank vapor samples collected when each core segment was removed). The samples weremore » radiologically released on September 28 and October 4, 1999, and received at the laboratory on September 29 and October 6, 1999. Target analytes were not detected at concentrations greater than their notification limits as specified in the SAP. Analytical results for the target analytes and tentatively identified compounds (TICs) are presented in Section 2.2.2 starting on page 2B-7. Three compounds identified for analysis in the SAP were analyzed as TICs. The discussion of this modification is presented in Section 2.2.1.2.« less

Removal of 137-Cs from Dissolved Hanford Tank Saltcake by Treatment with IE-911

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rapko, Brian M.; Sinkov, Sergei I.; Levitskaia, Tatiana G.

2003-12-09

The U.S. Department of Energy’s Richland Operations Office plans to accelerate the cleanup of the Hanford Site. Testing new technology for the accelerated cleanup will require dissolved saltcake from single-shell tanks. However, the 137Cs will need to be removed from the saltcake to alleviate radiation hazards. A saltcake composite constructed from archived samples from Hanford Site single-shell tanks 241-S-101, 241-S-109, 241-S-110, 241-S-111, 241-U-106, and 241-U-109 was dissolved in water, adjusted to 5 M Na, and transferred from the 222-S Laboratory to the Radiochemical Processing Laboratory (RPL). At the RPL, the approximately 5.5 liters of solution was passed through a 0.2-micronmore » polyethersulfone filter, collected, and homogenized. The filtered solution then was passed through an ion exchange column containing approximately 150 mL IONSIV® IE-911, an engineered form of crystalline silicotitanate available from UOP, at approximately 200 mL/hour in a continuous operation until all of the feed solution had been run through the column. An analysis of the 137Cs concentrations in the initial feed solution and combined column effluent indicates that > 99.999 percent of the Cs in the feed solution was removed by this operation. PNNR« less

Headspace vapor characterization of Hanford Waste Tank 241-S-102: Results from samples collected on January 26, 1996. Tank Vapor Characterization Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Evans, J.C.; Thomas, B.L.; Pool, K.H.

1996-07-01

This report describes the results of vapor samples obtained to compare vapor sampling of the tank headspace using the Vapor Sampling System (VSS) and In Situ Vapor Sampling System (ISVS) with and without particulate prefiltration. Samples were collected from the headspace of waste storage tank 241-S-102 (Tank S-102) at the Hanford Site in Washington State. Pacific Northwest National Laboratory (PNNL) was contracted by Westinghouse Hanford Company (WHC) to provide sampling devices and analyze samples for water, ammonia, permanent gases, total nonmethane hydrocarbons (TNMHCs, also known as TO-12), and organic analytes in samples collected in SUMMA{trademark} canisters and on triple sorbentmore » traps (TSTs) from the tank headspace. The analytical work was performed by the PNNL Vapor Analytical Laboratory (VAL) by the Tank Vapor Characterization Project. Work performed was based on a sampling and analysis plan (SAP) prepared by WHC. The SAP provided job-specific instructions for samples, analyses, and reporting. The SAP for this sample job was {open_quotes}Sampling and Analysis Plan for Tank Vapor Sampling Comparison Test{close_quote}, and the sample jobs were designated S6007, S6008, and S6009. Samples were collected by WHC on January 26, 1996, using the VSS, a truck-based sampling method using a heated probe; and the ISVS with and without particulate prefiltration.« less

Final Report for the Erosion-Corrosion Anaysis of Tank 241-AW-02E Feed Pump Pit Jumpers B-2 and 1-4 Removed from Service in 2013

DOE Office of Scientific and Technical Information (OSTI.GOV)

Page, Jason S.

2014-04-07

This document is the final report summarizing the results in the examination of two pipe sections (jumpers) from the tank 241-AW-02E feed pump pit in the 241-AW tank farm. These pipe section samples consisted of jumper AW02E-WT-J-[B – 2] and jumper AW02E-WT-J-[1 – 4]. For the remainder of this report, these jumpers will be referred to as B – 2 and 1 – 4.

Tank 241-S-111 08/1999 Compatibility Grab Samples and Analytical Results for the Final Report [SEC 1 and SEC 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

STEEN, F.H.

This document is the format IV, final report for the tank 241-S-111 (S-111) grab samples taken in August 1999 to address waste compatibility concerns. Chemical, radiochemical, and physical analyses on the tank S-111 samples were performed as directed in Compatibility Grab Sampling and Analysis Plan for Fiscal Year 1999 (Sasaki 1999a,b). Any deviations from the instructions provided in the tank sampling and analysis plan (TSAP) were discussed in this narrative. The notification limit for {sup 137}Cs was exceeded on two samples. Results are discussed in Section 5.3.2. No other notification limits were exceeded.

Performance evaluation of rotating pump jet mixing of radioactive wastes in Hanford Tanks 241-AP-102 and -104

DOE Office of Scientific and Technical Information (OSTI.GOV)

Onishi, Y.; Recknagle, K.P.

The purpose of this study was to confirm the adequacy of a single mixer pump to fully mix the wastes that will be stored in Tanks 241-AP-102 and -104. These Hanford double-shell tanks (DSTs) will be used as staging tanks to receive low-activity wastes from other Hanford storage tanks and, in turn, will supply the wastes to private waste vitrification facilities for eventual solidification. The TEMPEST computer code was applied to Tanks AP-102 and -104 to simulate waste mixing generated by the 60-ft/s rotating jets and to determine the effectiveness of the single rotating pump to mix the waste. TEMPESTmore » simulates flow and mass/heat transport and chemical reactions (equilibrium and kinetic reactions) coupled together. Section 2 describes the pump jet mixing conditions the authors evaluated, the modeling cases, and their parameters. Section 3 reports model applications and assessment results. The summary and conclusions are presented in Section 4, and cited references are listed in Section 5.« less

Precipitation of nitrate-cancrinite in Hanford Tank Sludge.

PubMed

Buck, E C; McNamara, B K

2004-08-15

The chemistry of underground storage tanks containing high-level waste at the Hanford Site in Washington State is an area of continued research interest. Thermodynamic models have predicted the formation of analcime and clinoptilolite in Hanford tanks, rather than cancrinite; however, these predictions were based on carbonate-cancrinite. We report the first observation of a nitrate-cancrinite [possibly Na8(K,Cs)(AlSiO4)6(NO3)2 x nH2O] extracted from a Hanford tank 241-AP-101 sample that was evaporated to 6, 8, and 10 M NaOH concentrations. The nitrate-cancrinite phase formed spherical aggregates (4 microm in diameter) that consisted of platy hexagonal crystals (approximately 0.2 microm thick). Cesium-137 was concentrated in these aluminosilicate structures. These phases possessed a morphology identical to that of nitrate-cancrinite synthesized using simulant tests of nonradioactive tank waste, supporting the contention that it is possible to develop nonradioactive artificial sludges. This investigation points to the continued importance of understanding the solubility of NO3-cancrinite and related phases. Knowledge of the detailed structure of actual phases in the tank waste helps with thermodynamic modeling of tank conditions and waste processing.

Removal of 137Cs from Dissolved Hanford Tank Saltcake by Treatment with IE-911

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rapko, Brian M.; Sinkov, Serguei I.; Levitskaia, Tatiana G.

2003-04-10

The U.S. Department of Energy's Richland Operations Office plans to accelerate the cleanup of the Hanford Site. Testing new technology for the accelerated cleanup will require dissolved saltcake from single-shell tanks. However, the 137Cs will need to be removed from the saltcake to alleviate radiation hazards. A saltcake composite constructed from archived samples from Hanford Single Shell Tanks 241-S-101, 241-S-109, 241-S-110, 241-S-111, 241-U-106, and 241-U-109 was dissolved in water, adjusted to 5 M Na, and transferred from the 222-S building to the Radiochemical Processing Laboratory (RPL). At the RPL, the approximately 5.5 liters of solution was passed through a 0.2-micronmore » polyethersulfone filter, collected, and homogenized. The filtered solution then was passed through an ion exchange column containing approximately 150 mL IONSIV IE-911, an engineered form of crystalline silicotitanate available from UOP, at approximately 200 mL/hour in a continuous operation until all of the feed solution had been run through the column. An analysis of the 137Cs concentrations in the initial feed solution and combined column effluent indicates that> 99.999 percent of the Cs in the feed solution was removed by this operation. This report describes the Cs-depletion operations together with a partial analysis of the as-received solution and a more extensive characterization of the Cs-depleted solution.« less

Tank vapor characterization project. Headspace vapor characterization of Hanford waste tank 241-BY-108: Second comparison study results from samples collected on 3/28/96

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thomas, B.L.; Pool, K.H.; Evans, J.C.

1997-01-01

This report describes the analytical results of vapor samples taken from the headspace of waste storage tank 241-BY-108 (Tank BY-108) at the Hanford Site in Washington State. The results described in this report is the second in a series comparing vapor sampling of the tank headspace using the Vapor Sampling System (VSS) and In Situ Vapor Sampling (ISVS) system without high efficiency particulate air (HEPA) prefiltration. The results include air concentrations of water (H{sub 2}O) and ammonia (NH{sub 3}), permanent gases, total non-methane organic compounds (TO-12), and individual organic analytes collected in SUMMA{trademark} canisters and on triple sorbent traps (TSTs).more » Samples were collected by Westinghouse Hanford Company (WHC) and analyzed by Pacific Northwest National Laboratory (PNNL). Analyses were performed by the Vapor Analytical Laboratory (VAL) at PNNL. Analyte concentrations were based on analytical results and, where appropriate, sample volume measurements provided by WHC.« less

Project W-211 initial tank retrieval systems year 2000 compliance assessment project plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

BUSSELL, J.H.

1999-08-24

This assessment describes the potential Year 2000 (Y2K) problems and describes the methods for achieving Y2K Compliance for Project W-211, Initial Tank Retrieval Systems (ITRS). The purpose of this assessment is to give an overview of the project. This document will not be updated and any dates contained in this document are estimates and may change. The scope of project W-211 is to provide systems for retrieval of radioactive wastes from ten double-shell tanks (DST). systems will be installed in tanks 102-AP, 104-AP, 105-AN, 104-AN, 102-AZ, 101-AW, 103-AN, 107-AN, 102-AY, and 102-SY. The current tank selection and sequence supports phasemore » I feed delivery to privatized processing plants. A detailed description of system dates, functions, interfaces, potential Y2K problems, and date resolutions can not be described since the project is in the definitive design phase. This assessment will describe the methods, protocols, and practices to assure that equipment and systems do not have Y2K problems.« less

Tank 241-AP-106, Grab samples, 6AP-98-1, 6AP-98-2 and 6AP-98-3 Analytical results for the final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

FULLER, R.K.

1999-02-23

This document is the final report for tank 241-AP-106 grab samples. Three grab samples 6AP-98-1, 6AP-98-2 and 6AP-98-3 were taken from riser 1 of tank 241-AP-106 on May 28, 1998 and received by the 222-S Laboratory on May 28, 1998. Analyses were performed in accordance with the ''Compatability Grab Sampling and Analysis Plan'' (TSAP) (Sasaki, 1998) and the ''Data Quality Objectives for Tank Farms Waste Compatability Program (DQO). The analytical results are presented in the data summary report. No notification limits were exceeded. The request for sample analysis received for AP-106 indicated that the samples were polychlorinated biphenyl (PCB) suspects.more » The results of this analysis indicated that no PCBs were present at the Toxic Substance Control Act (TSCA) regulated limit of 50 ppm. The results and raw data for the PCB analysis are included in this document.« less

Tank 241-U-103, grab samples 3U-99-1, 3u-99-2 and 3U-99-3

DOE Office of Scientific and Technical Information (OSTI.GOV)

STEEN, F.H.

This document is the final report for tank 241-U-103 grab samples. Three grab samples were collected from riser 13 on March 12, 1999 and received by the 222-S laboratory on March 15, 1999. Analyses were performed in accordance with the Compatibility Grab Sampling and Analysis Plan for Fiscal year 1999 (TSAP) and the Data Quality Objectives for Tank Farms Waste Compatibility Program (DQO). The analytical results are presented in the data summary report. None of the subsamples submitted for differential scanning calorimetry (DSC), total organic carbon (TOC) and plutonium 239 (Pu239) analyses exceeded the notification limits as stated in TSAP.

Tank Vapor Characterization Project: Tank 241-S-102 fourth temporal study: Headspace gas and vapor characterization results from samples collected on December 19, 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pool, K.H.; Evans, J.C.; Olsen, K.B.

1997-08-01

This report presents the results from analyses of samples taken from the headspace of waste storage tank 241-S-102 (Tank S-102) at the Hanford Site in Washington State. Tank headspace samples collected by SGN Eurisys Service Corporation (SESC) were analyzed by Pacific Northwest National Laboratory (PNNL) to determine headspace concentrations of selected non-radioactive analytes. Analyses were performed by the Vapor Analytical Laboratory (VAL) at PNNL. Vapor concentrations from sorbent trap samples are based on measured sample volumes provided by SESC. Ammonia was determined to be above the immediate notification limit of 150 ppm as specified by the sampling and analysis planmore » (SAP). Hydrogen was the principal flammable constituent of the Tank S-102 headspace, determined to be present at approximately 2.410% of its lower flammability limit (LFL). Total headspace flammability was estimated to be <2.973% of its lower flammability limit (LFL). Total headspace flammability was estimated to be <2.973% of the LFL. Average measured concentrations of targeted gases, inorganic vapors, and selected organic vapors are provided in Table S.1. A summary of experimental methods, including sampling methodology, analytical procedures, and quality assurance and control methods are presented in Section 2.0. Detailed descriptions of the analytical results are provided in Section 3.0.« less

Chemical Equilibrium of Aluminate in Hanford Tank Waste Originating from Tanks 241-AN-105 and 241-AP-108

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCoskey, Jacob K.; Cooke, Gary A.; Herting, Daniel L.

The purposes of the study described in this document follow; Determine or estimate the thermodynamic equilibrium of gibbsite in contact with two real tank waste supernatant liquids through both dissolution of gibbsite (bottom-up approach) and precipitation of aluminum-bearing solids (top-down approach); determine or estimate the thermodynamic equilibrium of a mixture of gibbsite and real tank waste saltcake in contact with real tank waste supernatant liquid through both dissolution of gibbsite and precipitation of aluminum-bearing solids; and characterize the solids present after equilibrium and precipitation of aluminum-bearing solids.

A demonstration of NIOSH push-pull ventilation criteria.

PubMed

Klein, M K

1987-03-01

This paper summarizes the results of a study performed on an actual chrome plating tank in order to validate criteria for push-pull ventilation systems developed by Huebener and Hughes at NIOSH. Validation of the criteria was made by taking area industrial hygiene samples for hexavalent and total chrome at ten locations around the plating tank. The sampling was performed during actual production runs or while the tank was operating with a dummy load. The sampling data are summarized. The data show that the push-pull system, operating at Huebener's criteria, could control emissions to below the current standards and guidelines. Conclusions and recommendations are included.

Characterization of Non-pertechnetate Species Relevant to the Hanford Tank Waste

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chatterjee, Sayandev; Andersen, Amity; Du, Yingge

Among radioactive constituents present in the tank waste stored at the U.S. DOE Hanford Site, technetium-99 (Tc), which is generated from the fission of 235U and 239Pu in high yields, presents a unique challenge in that it has a long half-life ( = 292 keV; T1/2 = 2.11105 y) and exists predominately in soluble forms in the liquid supernatant and salt cake fractions of the waste. In the strongly alkaline environments prevalent in most of the tank waste, its dominant chemical form is pertechnetate (TcO 4 -, oxidation state +7). However, attempts to remove Tc from the Hanford tank wastemore » using ion-exchange processes specific to TcO 4 - only met with limited success, particularly when processing tank waste samples containing elevated concentrations of organic complexants. This suggests that a significant fraction of the soluble Tc can be present as low-valent Tc (oxidation state < +7) (non-pertechnetate). The chemical identities of these non-pertechnetate species are poorly understood. Previous analysis of the SY-101 and SY-103 tank waste samples provided strong evidence that non-pertechnetate can be comprised of [fac-Tc(CO) 3] + complexes containing Tc in oxidation state +1 (Lukens et al. 2004). During the last three years, our team has expanded this work and demonstrated that high-ionic-strength solutions typifying tank waste supernatants promote oxidative stability of the [fac-Tc(CO) 3] + species (Rapko et al. 2013a; 2013b; Levitskaia et al. 2014; Chatterjee et al. 2015). Obtained results also suggest possible stabilization of Tc(VI) and potentially Tc(IV) oxidation states in the high-ionic-strength alkaline matrices particularly in the presence of organic chelators, so that Tc(IV, VI) can serve as important redox intermediates facilitating the reduction of Tc(VII) to Tc(I). Designing strategies for effective Tc management, including separation and immobilization, necessitates understanding the molecular structure of the non-pertechnetate species and their

The Integration of the 241-Z Building Decontamination and Decommissioning Under Cercla with RCRA Closure at the Plutonium Finishing Plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mattlin, E.; Charboneau, S.; Johnston, G.

2007-07-01

The 241-Z treatment and storage tanks, a hazardous waste Treatment, Storage and Disposal (TSD) unit permitted pursuant to the Resource Conservation and Recovery Act of 1976 (RCRA) and Washington State Hazardous Waste Management Act, RCW 70.105, , have been deactivated and are being actively decommissioned under the provisions of the Hanford Federal Facility Agreement and Consent Order (HFFACO), RCRA and Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) 42 U.S.C. 9601 et seq. The 241-Z TSD unit managed non-listed radioactive contaminated waste water, containing trace RCRA characteristic constituents. The 241-Z TSD unit consists of below grade tanks (D-4,more » D-5, D-7, D-8, and an overflow tank) located in a concrete containment vault, sample glovebox GB-2-241-ZA, and associated ancillary piping and equipment. The tank system is located beneath the 241-Z building. The 241-Z building is not a portion of the TSD unit. The sample glovebox is housed in the above-grade building. Waste managed at the TSD unit was received via underground piping from Plutonium Finishing Plant (PFP) sources. Tank D-6, located in the D-6 vault cell, is a past-practice tank that was taken out of service in 1972 and has never operated as a portion of the RCRA TSD unit. CERCLA actions will address Tank D-6, its containment vault cell, and soil beneath the cell that was potentially contaminated during past-practice operations and any other potential past-practice contamination identified during 241-Z closure, while outside the scope of the Hanford Facility Dangerous Waste Closure Plan, 241-Z Treatment and Storage Tanks. Under the RCRA closure plan, the 241-Z TSD unit is anticipated to undergo clean closure to the performance standards of the State of Washington with respect to dangerous waste contamination from RCRA operations. The TSD unit will be clean closed if physical closure activities identified in the plan achieve clean closure standards for all

Hanford Double-Shell Tank Extent-of-Condition Review - 15498

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, J. M.; Baide, D. D.; Barnes, T. J.

2014-11-19

During routine visual inspections of Hanford double-shell waste tank 241-AY-102 (AY-102), anomalies were identified on the annulus floor which resulted in further evaluations. Following a formal leak assessment in October 2012, Washington River Protection Solutions, LLC (WRPS) determined that the primary tank of AY-102 was leaking. A formal leak assessment, documented in RPP-ASMT-53793, Tank 241-AY-102 Leak Assessment Report, identified first-of-a-kind construction difficulties and trial-and-error repairs as major contributing factors to tank failure.1 To determine if improvements in double-shell tank (DST) construction occurred after construction of tank AY-102, a detailed review and evaluation of historical construction records was performed for Hanford’smore » remaining twenty-seven DSTs. Review involved research of 241 boxes of historical project documentation to better understand the condition of the Hanford DST farms, noting similarities in construction difficulties/issues to tank AY-102. Information gathered provides valuable insight regarding construction difficulties, future tank operations decisions, and guidance of the current tank inspection program. Should new waste storage tanks be constructed in the future, these reviews also provide valuable lessons-learned.« less

Spectroscopic Properties of Tc(I) Tricarbonyl Species Relevant to the Hanford Tank Waste

DOE Office of Scientific and Technical Information (OSTI.GOV)

Levitskaia, Tatiana G.; Andersen, Amity; Chatterjee, Sayandev

2015-12-04

Technetium-99 (Tc) exists predominately in soluble forms in the liquid supernatant and salt cake fractions of the nuclear tank waste stored at the U.S. DOE Hanford Site. In the strongly alkaline environments prevalent in the tank waste, its dominant chemical form is pertechnetate (TcO4-, oxidation state +7). However, attempts to remove Tc from the Hanford tank waste using ion-exchange processes specific to TcO 4 - only met with limited success, particularly processing tank waste samples containing elevated concentrations of organic complexants. This suggests that a significant fraction of the soluble Tc can be present as non-pertechnetate low-valent Tc (oxidation statemore » < +7) (non-pertechnetate). The chemical identities of these non-pertechnetate species are poorly understood. Previous analysis of the SY-101 and SY-103 tank waste samples provided strong evidence that non-pertechnetate can be comprised of [Tc(CO) 3] + complexes containing Tc in oxidation state +1 (Lukens et al. 2004). During the last two years, our team has expanded this work and demonstrated that high-ionic-strength solutions typifying tank waste supernatants promote oxidative stability of the [Tc(CO) 3] + species (Rapko et al. 2013; Levitskaia et al. 2014). It also was observed that high-ionic-strength alkaline matrices stabilize Tc(VI) and potentially Tc(IV) oxidation states, particularly in presence organic chelators, suggesting that the relevant Tc compounds can serve as important redox intermediates facilitating the reduction of Tc(VII) to Tc(I). Designing strategies for effective Tc processing, including separation and immobilization, necessitates understanding the molecular structure of these non-pertechnetate species and their identification in the actual tank waste samples. To-date, only limited information exists regarding the nature and characterization of the Tc(I), Tc(IV), and Tc(VI) species. One objective of this project is to identify the form of non-pertechnetate in the

In-Tank Processing (ITP) Geotechnical Summary Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cumbest, R.J.

A geotechnical investigation has been completed for the In Tank Processing Facility (ITP) which consists of buildings 241-96H and 241-32H; and Tanks 241-948H, 241-949H, 241-950H, and 241-951H. The investigation consisted of a literature search for relevant technical data, field explorations, field and laboratory testing, and analyses. This document presents a summary of the scope and results to date of the investigations and engineering analyses for these facilities. A final geotechnical report, which will include a more detailed discussion and all associated boring logs, laboratory test results, and analyses will be issued in October 1994.The purpose of the investigation is tomore » obtain geotechnical information to evaluate the seismic performance of the foundation materials and embankme nts under and around the ITP. The geotechnical engineering objectives of the investigation are to: 1) define the subsurface stratigraphy, 2) obtain representative engineering properties of the subsurface materials, 3) assess the competence of the subsurface materials under static and dynamic loads, 4) derive properties for seismic soil-structure interaction analysis, 5) evaluate the areal and vertical extent of horizons that might cause dynamic settlement or instability, and 6) determine settlement at the foundation level of the tanks.« less

Vapor space characterization of Waste Tank 241-TY-104 (in situ): Results from samples collected on 8/5/94

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ligotke, M.W.; Pool, K.H.; Lucke, R.B.

1995-10-01

This report describes inorganic and organic analyses results from in situ samples obtained from the headspace of the Hanford waste storage Tank 241-TY-104 (referred to as Tank TY-104). The results described here were obtained to support safety and toxicological evaluations. A summary of the results for inorganic and organic analytes is listed in Table 1. Detailed descriptions of the results appear in the text. Quantitative results were obtained for the inorganic compounds ammonia (NH{sub 3}), nitrogen dioxide (NO{sub 2}), nitric oxide (NO), and water (H{sub 2}O). Sampling for hydrogen cyanide (HCN) and sulfur oxides (SO{sub x}) was not performed. Inmore » addition, the authors looked for the 39 TO-14 compounds plus an additional 14 analytes. Of these, eight were observed above the 5-ppbv reporting cutoff. Twenty-four organic tentatively identified compounds (TICs) were observed above the reporting cutoff of (ca.) 10 ppbv and are reported with concentrations that are semiquantitative estimates based on internal standard response factors. The 10 organic analytes with the highest estimated concentrations are listed in Table 1 and account for approximately 86% of the total organic components in Tank TY-104. Tank TY-104 is on the Ferrocyanide Watch List.« less

Single-Shell Tanks Leak Integrity Elements/ SX Farm Leak Causes and Locations - 12127

DOE Office of Scientific and Technical Information (OSTI.GOV)

Girardot, Crystal; Harlow, Don; Venetz, Theodore

2012-07-01

Washington River Protection Solutions, LLC (WRPS) developed an enhanced single-shell tank (SST) integrity project in 2009. An expert panel on SST integrity was created to provide recommendations supporting the development of the project. One primary recommendation was to expand the leak assessment reports (substitute report or LD-1) to include leak causes and locations. The recommendation has been included in the M-045-91F Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) as one of four targets relating to SST leak integrity. The 241-SX Farm (SX Farm) tanks with leak losses were addressed on an individual tank basis as part of LD-1.more » Currently, 8 out of 23 SSTs that have been reported to having a liner leak are located in SX Farm. This percentage was the highest compared to other tank farms which is why SX Farm was analyzed first. The SX Farm is comprised of fifteen SSTs built 1953-1954. The tanks are arranged in rows of three tanks each, forming a cascade. Each of the SX Farm tanks has a nominal 1-million-gal storage capacity. Of the fifteen tanks in SX Farm, an assessment reported leak losses for the following tanks: 241-SX-107, 241-SX-108, 241-SX-109, 241-SX- 111, 241-SX-112, 241-SX-113, 241-SX-114 and 241-SX-115. The method used to identify leak location consisted of reviewing in-tank and ex-tank leak detection information. This provided the basic data identifying where and when the first leaks were detected. In-tank leak detection consisted of liquid level measurement that can be augmented with photographs which can provide an indication of the vertical leak location on the sidewall. Ex-tank leak detection for the leaking tanks consisted of soil radiation data from laterals and dry-wells near the tank. The in-tank and ex-tank leak detection can provide an indication of the possible leak location radially around and under the tank. Potential leak causes were determined using in-tank and ex-tank information that is not directly

SINGLE-SHELL TANKS LEAK INTEGRITY ELEMENTS/SX FARM LEAK CAUSES AND LOCATIONS - 12127

DOE Office of Scientific and Technical Information (OSTI.GOV)

VENETZ TJ; WASHENFELDER D; JOHNSON J

2012-01-25

Washington River Protection Solutions, LLC (WRPS) developed an enhanced single-shell tank (SST) integrity project in 2009. An expert panel on SST integrity was created to provide recommendations supporting the development of the project. One primary recommendation was to expand the leak assessment reports (substitute report or LD-1) to include leak causes and locations. The recommendation has been included in the M-045-9IF Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) as one of four targets relating to SST leak integrity. The 241-SX Farm (SX Farm) tanks with leak losses were addressed on an individual tank basis as part of LD-1.more » Currently, 8 out of 23 SSTs that have been reported to having a liner leak are located in SX Farm. This percentage was the highest compared to other tank farms which is why SX Farm was analyzed first. The SX Farm is comprised of fifteen SSTs built 1953-1954. The tanks are arranged in rows of three tanks each, forming a cascade. Each of the SX Farm tanks has a nominal I-million-gal storage capacity. Of the fifteen tanks in SX Farm, an assessment reported leak losses for the following tanks: 241-SX-107, 241-SX-108, 241-SX-109, 241-SX-111, 241-SX-112, 241-SX-113, 241-SX-114 and 241-SX-115. The method used to identify leak location consisted of reviewing in-tank and ex-tank leak detection information. This provided the basic data identifying where and when the first leaks were detected. In-tank leak detection consisted of liquid level measurement that can be augmented with photographs which can provide an indication of the vertical leak location on the sidewall. Ex-tank leak detection for the leaking tanks consisted of soil radiation data from laterals and drywells near the tank. The in-tank and ex-tank leak detection can provide an indication of the possible leak location radially around and under the tank. Potential leak causes were determined using in-tank and ex-tank information that is not directly

Computer system design description for SY-101 hydrogen mitigation test project data acquisition and control system (DACS-1)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ermi, A.M.

1997-05-01

Description of the Proposed Activity/REPORTABLE OCCURRENCE or PIAB: This ECN changes the computer systems design description support document describing the computers system used to control, monitor and archive the processes and outputs associated with the Hydrogen Mitigation Test Pump installed in SY-101. There is no new activity or procedure associated with the updating of this reference document. The updating of this computer system design description maintains an agreed upon documentation program initiated within the test program and carried into operations at time of turnover to maintain configuration control as outlined by design authority practicing guidelines. There are no new crediblemore » failure modes associated with the updating of information in a support description document. The failure analysis of each change was reviewed at the time of implementation of the Systems Change Request for all the processes changed. This document simply provides a history of implementation and current system status.« less

Applying Hanford Tank Mixing Data to Define Pulse Jet Mixer Operation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wells, Beric E.; Bamberger, Judith A.; Recknagle, Kurtis P.

solids. Jet mixer pumps were used in Hanford waste tank 241-AZ-101, and at least 95% of the 0.46-m (18-in.) deep sediment, with a shear strength of 1,500 to 4,200 Pa, was mobilized. Solids with a median particle size of 43 μm, 90th percentile of 94μm, were suspended in tank 241-AZ-101 to at least 5.5 m (216 in.) above the vessel bottom. Analytical calculations for this jet mixer pump test were used to estimate the velocities and wall shear stress that mobilized and suspended the waste. These velocities and wall shear stresses provide design threshold criteria which are metrics for system performance that can be evaluated via testing. If the fluid motion in a specific pulse jet mixed process vessel meets or exceeds the fluid motion of the demonstrated performance in the WFD system, confidence is provided that that vessel will similarly mobilize and suspend those solids if they were within the WTP. The single PJM CFD-calculated jet velocity and wall shear stress compare favorably with the design threshold criterion estimated for the tank 241-AZ-101 process data. Therefore, for both mobilization and suspension, the performance data evaluated from the WFD system testing increases confidence that the performance of the pulse jet mixed process vessels will be sufficient to process that waste even if that waste is not fully characterized.« less

Results of Characterization and Retrieval Testing on Tank 241-C-110 Heel Solids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Callaway, William S.

2013-09-30

Nine samples of heel solids from tank 241-C-110 were delivered to the 222-S Laboratory for characterization and dissolution testing. After being drained thoroughly, the sample solids were primarily white to light-brown with minor dark-colored inclusions. The maximum dimension of the majority of the solids was <2 mm; however, numerous pieces of aggregate, microcrystalline, and crystalline solids with maximum dimensions ranging from 5-70 mm were observed. In general, the larger pieces of aggregate solids were strongly cemented. Natrophosphate [Na{sub 7}F(PO{sub 4}){sub 2}°19H{sub 2}O] was the dominant solid phase identified in the heel solids. Results of chemical analyses suggested that 85-87 wt%more » of the heel solids were the fluoridephosphate double salt. The average bulk density measured for the heel solids was 1.689 g/mL; the reference density of natrophosphate is 1.71 g/mL. Dissolution tests on composite samples indicate that 94 to 97 wt% of the tank 241-C-110 heel solids can be retrieved by dissolution in water. Dissolution and recovery of the soluble components in 1 kg (0.59 L) of the heel solids required the addition of ≈9.5 kg (9.5 L) of water at 15 °C and ≈4.4 kg (4.45 L) of water at 45 °C. Calculations performed using the Environmental Simulation Program indicate that dissolution of the ≈0.86 kg of natrophosphate in each kilogram of the tank 241-C-110 heel solids would require ≈9.45 kg of water at 15 °C and ≈4.25 kg of water at 45 °C. The slightly larger quantities of water determined to be required to retrieve the soluble components in 1 kg of the heel solids are consistent with that required for the dissolution of solids composed mainly of natrophosphate with a major portion of the balance consisting of highly soluble sodium salts. At least 98% of the structural water, soluble phosphate, sodium, fluoride, nitrate, carbonate, nitrite, sulfate, oxalate, and chloride in the test composites was dissolved and recovered in the dissolution

DOE Office of Scientific and Technical Information (OSTI.GOV)

Girardot, Crystal L.; Harlow, Donald G.

This document identifies 241-C Tank Farm (C Farm) leak causes and locations for the 100 series leaking tanks (241-C-101 and 241-C-105) identified in RPP-RPT-33418, Rev. 2, Hanford C-Farm Leak Inventory Assessments Report. This document satisfies the C Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

Waste Feed Delivery System Phase 1 Preliminary Reliability and Availability and Maintainability Analysis [SEC 1 and 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

CARLSON, A.B.

The document presents updated results of the preliminary reliability, availability, maintainability analysis performed for delivery of waste feed from tanks 241-AZ-101 and 241-AN-105 to British Nuclear Fuels Limited, inc. under the Tank Waste Remediation System Privatization Contract. The operational schedule delay risk is estimated and contributing factors are discussed.

FINAL ANALYTICAL RESULTS FROM THE EXAMINATION OF CORROSION ON SECTIONS OF CORROSION PROBE REMOVED FROM TANK 241-AN-107 ON 08/10/2006

DOE Office of Scientific and Technical Information (OSTI.GOV)

DUNCAN JB; COOKE GA

2007-03-22

Tank Farms Operations removed an electrochemical noise probe from Tank 241-AN-107. In the field, the probe was cut into four sections, wrapped, and placed in a 55-gallon drum, This drum was delivered to the 222-S Laboratory. The 222 S Laboratory unpackaged the sections of the AN-107 electrochemical noise probe and examined the material for evidence of corrosion. Each of the four sections contained three C-ring and three bullet specimens. The specimens were examined for pitting corrosion, crevice corrosion, and stress corrosion cracking. No evidence of stress corrosion cracking was found in the stressed C-ring specimens. Minor pitting was evident onmore » some surfaces. Crevice corrosion was the dominant type of corrosion observed.« less

Chemical and chemically-related considerations associated with sluicing tank C-106 waste to tank AY-102

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reynolds, D.A.

1997-04-04

New data on tank 241-C-106 were obtained from grab sampling and from compatibility testing of tank C-106 and tank AY-102 wastes. All chemistry-associated and other compatibility Information compiled in this report strongly suggests that the sluicing of the contents of tank C-106, in accord with appropriate controls, will pose no unacceptable risk to workers, public safety, or the environment. In addition, it is expected that the sluicing operation will successfully resolve the High-Heat Safety Issue for tank C-106.

Final report for tank 241-AP-108, grab samples 8AP-96-1, 8AP-96-2 and 8AP-96-FB

DOE Office of Scientific and Technical Information (OSTI.GOV)

Esch, R.A.

1996-04-19

This document is the final report deliverable for the tank 241-AP-108 grab samples. The samples were subsampled and analyzed in accordance with the TSAP. Included in this report are the results for the Waste Compatibility analyses, with the exception of DSC and thermogravimetric analysis (TGA) results which were presented in the 45 Day report (Part 2 of this document). The raw data for all analyses, with the exception of DSC and TGA, are also included in this report.

Residual waste from Hanford tanks 241-C-203 and 241-C-204. 2. Contaminant release model.

PubMed

Cantrell, Kirk J; Krupka, Kenneth M; Deutsch, William J; Lindberg, Michael J

2006-06-15

Release of U and 99Tc from residual sludge in Hanford waste tanks 241-C-203 and 241-C-204 atthe U.S. Department of Energy's (DOE) Hanford Site in southeastern Washington state was quantified by water-leaching, selective extractions, empirical solubility measurements, and thermodynamic modeling. A contaminant release model was developed based on these experimental results and solid-phase characterization results presented elsewhere. Uranium release was determined to be controlled by two phases and occurred in three stages. In the first stage, U release is controlled by the solubility of tejkaite, which is suppressed by high concentrations of sodium released from the dissolution of NaNO3 in the residual sludges. Equilibrium solubility calculations indicate the U released during this stage will have a maximum concentration of 0.021 M. When all the NaNO3 has dissolved from the sludge, the solubility of the remaining cejkaite will increase to 0.28 M. After cejkaite has completely dissolved, the majority of the remaining U is in the form of poorly crystalline Na2U2O7 [or clarkeite Na[(UO2)O(OH)](H20)0-1]. In contact with Hanford groundwater this phase is not stable, and becquerelite becomes the U solubility controlling phase, with a calculated equilibrium concentration of 1.2 x 10(-4) M. For Tc, a significant fraction of its concentration in the residual sludge was determined to be relatively insoluble (20 wt % for C-203 and 80 wt % for C-204). Because of the low concentrations of Tc in these sludge materials, the characterization studies did not identify any discrete Tc solids phases. Release of the soluble fraction of Tc was found to occur concomitantly with NO3-. It was postulated that a NaNO3-NaTcO4 solid solution could be responsible for this behavior. The Tc release concentrations for the soluble fraction were estimated to be 2.4 x 10-6 M for C-203 and 2.7 x 10(-5) M for C-204. Selective extraction results indicated that the recalcitrant fraction of Tc was

THE INTEGRATION OF THE 241-Z BUILDING DECONTAMINATION & DECOMMISSIONING (D&D) UNDER COMPREHENSIVE ENVIRONMENTAL RESPONSE COMPENSATION & LIABILITY ACT (CERCLA) WITH RESOURCE CONSERVATION & RECOVERY ACT (RCRA) CLOSURE AT THE PLUTONIUM FINISHING PLANT (PFP)

DOE Office of Scientific and Technical Information (OSTI.GOV)

HOPKINS, A.M.

2007-02-20

The 241-Z treatment and storage tanks, a hazardous waste Treatment, Storage and Disposal (TSD) unit permitted pursuant to the ''Resource Conservation and Recovery Act of 1976'' (RCRA) and Washington State ''Hazardous Waste Management Act, RCW 70.105'', have been deactivated and are being actively decommissioned. The 241-Z TSD unit managed non-listed radioactive contaminated waste water, containing trace RCRA characteristic constituents. The 241-Z TSD unit consists of below grade tanks (D-4, D-5, D-7, D-8, and an overflow tank) located in a concrete containment vault, sample glovebox GB-2-241-ZA, and associated ancillary piping and equipment. The tank system is located beneath the 241-Z building.more » The 241-Z building is not a portion of the TSD unit. The sample glovebox is housed in the above-grade building. Waste managed at the TSD unit was received via underground mining from Plutonium Finishing Plant (PFP) sources. Tank D-6, located in the D-6 vault cell, is a past-practice tank that was taken out of service in 1972 and has never operated as a portion of the RCRA TSD unit. CERCLA actions address Tank D-6, its containment vault cell, and soil beneath the cell that was potentially contaminated during past-practice operations and any other potential past-practice contamination identified during 241-Z closure, while outside the scope of the ''Hanford Facility Dangerous Waste Closure Plant, 241-Z Treatment and Storage Tanks''.« less

Small Column Testing of Superlig 639 for Removal of 99Tc from Hanford Tank Waste Envelope C (Tank 241-AN-107)

DOE Office of Scientific and Technical Information (OSTI.GOV)

DL Blanchard; DE Kurath; BM Rapko

The current BNFL Inc. flow sheet for pretreating Hanford High-Level tank wastes includes the use of Superlig(reg.sign)639 (SL-639) in a dual column system for removing technetium-99 ({sup 99}Tc) from the aqueous fraction of the waste. This sorbent material has been developed and supplied by IBC Advanced Technologies, Inc., American Fork, UT. This report documents the results of testing the SL-639 sorbent with diluted waste [Na{sup +}] {approx} 5 M from Tank 241-AN-107 (an Envelope C waste, abbreviated AN-107) at Battelle Northwest Laboratories (BNW). The equilibrium behavior was assessed with batch contacts between the sorbent and the waste. Two AN-107 samplesmore » were used: (1) an archived sample from previous testing and (2) a more recent sample collected specifically for BNFL. A portion of the archive sample and all of the BNFL sample were treated to remove Sr-90 and transuranic elements (TRU). All samples had also been Cs decontaminated by ion exchange (IX), and were spiked with a technetium-95m ({sup 95m}Tc) pertechnetate tracer, {sup 95m}TcO{sub 4}{sup -}.The TcO{sub 4}{sup -} and total Tc K{sub d} values, assumed equal to the {sup 95m}Tc and {sup 99}Tc K{sub d}'s, respectively, are shown in Table S1. Values are averages of duplicates, which showed significant scatter. The total Tc K{sub d} for the BNFL sample is much lower than the TcO{sub 4}{sup -}, indicating that a large fraction of the {sup 99}Tc is not pertechnetate.« less

Hydrogen Safety Project: Chemical analysis support task. Window ``E`` analyses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, T E; Campbell, J A; Hoppe, E W

1992-09-01

Core samples taken from tank 101-SY at Hanford during ``window E`` were analyzed for organic and radiochemical constituents by staff of the Analytical Chemistry Laboratory at Pacific Northwest Laboratory. Westinghouse Hanford company submitted these samples to the laboratory.

Ion Exchange Studies for Removal of Sulfate from Hanford Tank Waste Envelope C (241-AN-107) Using SuperLig 655 Resin

DOE Office of Scientific and Technical Information (OSTI.GOV)

DE Kurath; JR Bontha; DL Blanchard

BNFL Inc. is evaluating various pretreatment technologies to mitigate the impacts of sulfate on the LAW vitrification system. One pretreatment technology for separating sulfate from LAW solutions involves the use of SuperLig{reg_sign} 655 (SL-655), a proprietary ion exchange material developed and supplied by IBC Advanced Technologies, Inc., American Fork, UT. This report describes testing of SL-655 with diluted ([Na] {approximately} 5 M) waste from Hanford Tank 241-AN-107 at Battelle, Pacific Northwest Division. Batch contact studies were conducted from 4 to 96 hours to determine the sulfate distribution coefficient and reaction kinetics. A small-scale ion exchange column test was conducted tomore » evaluate sulfate removal, loading, breakthrough, and elution from the SL-655. In all of these tests, an archived 241-AN-107 tank waste sample (pretreated to remove Cs, Sr, and transuranics elements) was used. The experimental details and results are described in this report. Under the test conditions, SL-655 was found to have no significant ion exchange affinity for sulfate in this matrix. The batch contact study resulted in no measurable difference in the aqueous sulfate concentration following resin contact (K{sub d} {approximately} 0). The column test also demonstrated SL-655 had no practical affinity for sulfate in the tested matrix. Within experimental error, the sulfate concentration in the column effluent was equal to the concentration in the feed after passing 3 bed volumes of sample through the columns. Furthermore, some, if not all, of the decreased sulfate concentration in these first three column volumes of effluent can be ascribed to mixing and dilution of the 241-AN-107 feed with the interstitial liquid present in the column at the start of the loading cycle. Finally, ICP-AES measurements on the eluate solutions showed the presence of barium as soon as contact with the feed solution is completed. Barium is a metal not detected in the feed solution

Development and Demonstration of a Sulfate Precipitation Process for Hanford Waste Tank 241-AN-107

DOE Office of Scientific and Technical Information (OSTI.GOV)

SK Fiskum; DE Kurath; BM Rapko

2000-08-16

A series of precipitation experiments were conducted on Hanford waste tank 241-AN-107 samples in an effort to remove sulfate from the matrix. Calcium nitrate was added directly to AN-107 sub-samples to yield several combinations of Ca:CO{sub 3} mole ratios spanning a range of 0:1 to 3:1 to remove carbonate as insoluble CaCO{sub 3}. Similarly barium nitrate was added directly to the AN-107 aliquots, or to the calcium pretreated AN-107 aliquots, giving of Ba:SO{sub 4} mole ratios spanning a range of 1:1 to 5:1 to precipitate sulfate as BaSO{sub 4}. Initial bulk carbonate removal was required for successful follow-on barium sulfatemore » precipitation. A {ge} 1:1 mole ratio of Ca:CO{sub 3} was found to lower the carbonate concentration such that Ba would react preferentially with the sulfate. A follow-on 1:1 mole ratio of Ba:SO{sub 4} resulted in 70% sulfate removal. The experiment was scaled up with a 735-mL aliquot of AN-107 for more complete testing. Calcium carbonate and barium sulfate settling rates were determined and fates of selected cations, anions, and radionuclides were followed through the various process steps. Seventy percent of the sulfate was removed in the scale-up test while recovering 63% of the filtrate volume. Surprisingly, during the scale-up test a sub-sample of the CaCO{sub 3}/241-AN-107 slurry was found to lose fluidity upon standing for {le} 2 days. Metathesis with BaCO{sub 3} at ambient temperature was also evaluated using batch contacts at various BaCO{sub 3}:SO{sub 4} mole ratios with no measurable success.« less

New rain shed (Building No. 241), overhead pipeline and raw ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

New rain shed (Building No. 241), overhead pipeline and raw water tank T4. Distribution pump house can be seen at the center of building. - Hawaii Volcanoes National Park Water Collection System, Hawaii Volcanoes National Park, Volcano, Hawaii County, HI

Significant volume reduction of tank waste by selective crystallization: 1994 Annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Herting, D.L.; Lunsford, T.R.

1994-09-27

The objective of this technology task plan is to develop and demonstrate a scaleable process of reclaim sodium nitrate (NaNO{sub 3}) from Hanford waste tanks as a clean nonradioactive salt. The purpose of the so-called Clean Salt Process is to reduce the volume of low level waste glass by as much as 70%. During the reporting period of October 1, 1993, through May 31, 1994, progress was made on four fronts -- laboratory studies, surrogate waste compositions, contracting for university research, and flowsheet development and modeling. In the laboratory, experiments with simulated waste were done to explore the effects ofmore » crystallization parameters on the size and crystal habit of product NaNO{sub 3} crystals. Data were obtained to allows prediction of decontamination factor as a function of solid/liquid separation parameters. Experiments with actual waste from tank 101-SY were done to determine the extent of contaminant occlusions in NaNO{sub 3} crystals. In preparation for defining surrogate waste compositions, single shell tanks were categorized according to the weight percent NaNO{sub 3} in each tank. A detailed process flowsheet and computer model were created using the ASPENPlus steady state process simulator. This is the same program being used by the Tank Waste Remediation System (TWRS) program for their waste pretreatment and disposal projections. Therefore, evaluations can be made of the effect of the Clean Salt Process on the low level waste volume and composition resulting from the TWRS baseline flowsheet. Calculations, using the same assumptions as used for the TWRS baseline where applicable indicate that the number of low level glass vaults would be reduced from 44 to 16 if the Clean Salt Process were incorporated into the baseline flowsheet.« less

49 CFR 179.101-1 - Individual specification requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120) § 179.101-1... than 1/2 inch. 4 Tank cars not equipped with a thermal protection or an insulation system used for the...

49 CFR 179.101-1 - Individual specification requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120) § 179.101-1... than 1/2 inch. 4 Tank cars not equipped with a thermal protection or an insulation system used for the...

49 CFR 179.101-1 - Individual specification requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120) § 179.101-1... than 1/2 inch. 4 Tank cars not equipped with a thermal protection or an insulation system used for the...

Push/Push Fastener

NASA Technical Reports Server (NTRS)

Jackson, Steven A.

1996-01-01

Modified version of Nylatch (or equivalent) commerical quick-connect/quick-disconnect fastener for joining flat panels. Fastener tightened by pushing on knob on one side and loosened by pushing on knob on other side. Push/push operation of fastener advantageous in cold or otherwise hostile environments where gloves worn, in underwater operations, or if person handicapped.

10 CFR 431.101 - Purpose and scope.

Code of Federal Regulations, 2011 CFR

2011-01-01

... EQUIPMENT Commercial Water Heaters, Hot Water Supply Boilers and Unfired Hot Water Storage Tanks § 431.101... heaters, hot water supply boilers and unfired hot water storage tanks, pursuant to Part C of Title III of...

10 CFR 431.101 - Purpose and scope.

Code of Federal Regulations, 2012 CFR

2012-01-01

... EQUIPMENT Commercial Water Heaters, Hot Water Supply Boilers and Unfired Hot Water Storage Tanks § 431.101... heaters, hot water supply boilers and unfired hot water storage tanks, pursuant to Part C of Title III of...

10 CFR 431.101 - Purpose and scope.

Code of Federal Regulations, 2013 CFR

2013-01-01

... EQUIPMENT Commercial Water Heaters, Hot Water Supply Boilers and Unfired Hot Water Storage Tanks § 431.101... heaters, hot water supply boilers and unfired hot water storage tanks, pursuant to Part C of Title III of...

10 CFR 431.101 - Purpose and scope.

Code of Federal Regulations, 2014 CFR

2014-01-01

... EQUIPMENT Commercial Water Heaters, Hot Water Supply Boilers and Unfired Hot Water Storage Tanks § 431.101... heaters, hot water supply boilers and unfired hot water storage tanks, pursuant to Part C of Title III of...

PLUTONIUM FINISHING PLANT (PFP) 241-Z LIQUID WASTE TREATMENT FACILITY DEACTIVATION AND DEMOLITION

DOE Office of Scientific and Technical Information (OSTI.GOV)

JOHNSTON GA

2008-01-15

Fluor Hanford, Inc. (FH) is proud to submit the Plutonium Finishing Plant (PFP) 241-Z liquid Waste Treatment Facility Deactivation and Demolition (D&D) Project for consideration by the Project Management Institute as Project of the Year for 2008. The decommissioning of the 241-Z Facility presented numerous challenges, many of which were unique with in the Department of Energy (DOE) Complex. The majority of the project budget and schedule was allocated for cleaning out five below-grade tank vaults. These highly contaminated, confined spaces also presented significant industrial safety hazards that presented some of the most hazardous work environments on the Hanford Site.more » The 241-Z D&D Project encompassed diverse tasks: cleaning out and stabilizing five below-grade tank vaults (also called cells), manually size-reducing and removing over three tons of process piping from the vaults, permanently isolating service utilities, removing a large contaminated chemical supply tank, stabilizing and removing plutonium-contaminated ventilation ducts, demolishing three structures to grade, and installing an environmental barrier on the demolition site . All of this work was performed safely, on schedule, and under budget. During the deactivation phase of the project between November 2005 and February 2007, workers entered the highly contaminated confined-space tank vaults 428 times. Each entry (or 'dive') involved an average of three workers, thus equaling approximately 1,300 individual confined -space entries. Over the course of the entire deactivation and demolition period, there were no recordable injuries and only one minor reportable skin contamination. The 241-Z D&D Project was decommissioned under the provisions of the 'Hanford Federal Facility Agreement and Consent Order' (the Tri-Party Agreement or TPA), the 'Resource Conservation and Recovery Act of 1976' (RCRA), and the 'Comprehensive Environmental Response, Compensation, and Liability Act of 1980' (CERCLA

Contaminant Leach Testing of Hanford Tank 241-C-104 Residual Waste

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cantrell, Kirk J.; Snyder, Michelle M.V.; Wang, Guohui

2015-07-01

Leach testing of Tank C-104 residual waste was completed using batch and column experiments. Tank C-104 residual waste contains exceptionally high concentrations of uranium (i.e., as high as 115 mg/g or 11.5 wt.%). This study was conducted to provide data to develop contaminant release models for Tank C-104 residual waste and Tank C-104 residual waste that has been treated with lime to transform uranium in the waste to a highly insoluble calcium uranate (CaUO4) or similar phase. Three column leaching cases were investigated. In the first case, C-104 residual waste was leached with deionized water. In the second case, crushedmore » grout was added to the column so that deionized water contacted the grout prior to contacting the waste. In the third case, lime was mixed in with the grout. Results of the column experiments demonstrate that addition of lime dramatically reduces the leachability of uranium from Tank C-104 residual waste. Initial indications suggest that CaUO4 or a similar highly insoluble calcium rich uranium phase forms as a result of the lime addition. Additional work is needed to definitively identify the uranium phases that occur in the as received waste and the waste after the lime treatment.« less

Methods for heel retrieval for tanks C-101, C-102, and C-111 at the Hanford Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sams, Terry L.; Kirch, N. W.; Reynolds, Jacob G.

The purpose of this paper is to evaluate the prospects of using bulk waste characteristics to determine the most appropriate heel retrieval technology. If the properties of hard to remove heels can be determined before bulk retrieval, then a heel retrieval technology can be selected before bulk retrieval is complete. This would save substantially on sampling costs and would allow the deployment of the heel retrieval technology immediately after bulk retrieval. The latter would also accelerate the heel removal schedule. A number of C-farm retrievals have been fully or partially completed at the time of this writing. Thus, there ismore » already substantial information on the success of different technologies and the composition of the heels. There is also substantial information on the waste types in each tank based on historical records. Therefore, this study will correlate the performance of technologies used so far and compare them to the known waste types in the tanks. This will be used to estimate the performance of future C Farm heel retrievals. An initial decision tree is developed and employed on tanks C-101, C-102, and C 111. An assumption of this study is that no additional characterization information would be available, before or after retrieval. Note that collecting additional information would substantially increase the probability of success. Deploying some in-situ testing technologies, such as a water lance or an in-situ Raman probe, might substantially increase the probability of successfully selecting the process conditions without having to take samples from the tanks for laboratory analysis.« less

Endothelial cell-derived exosomes protect SH-SY5Y nerve cells against ischemia/reperfusion injury.

PubMed

Xiao, Bing; Chai, Yi; Lv, Shigang; Ye, Minhua; Wu, Miaojing; Xie, Liyuan; Fan, Yanghua; Zhu, Xingen; Gao, Ziyun

2017-10-01

Cerebral ischemia is a leading cause of death and disability. A previous study indicated that remote ischemic postconditioning (RIP) in the treatment of cerebral ischemia reduces ischemia/reperfusion (I/R) injury. However, the underlying mechanism is not well understood. In the present study, the authors hypothesized that the protective effect of RIP on neurological damage is mediated by exosomes that are released by endothelial cells in femoral arteries. To test this, right middle cerebral artery occlusion/reperfusion with RIP was performed in rats. In addition, an I/R injury cell model was tested that included human umbilical vein endothelial cells (HUVECs) and SH-SY5Y cells. Both the in vivo and in vitro models were examined for injury. Markers of exosomes (CD63, HSP70 and TSG101) were assessed by immunohistochemistry, western blot analysis and flow cytometry. Exosomes were extracted from both animal serum and HUVEC culture medium and identified by electron microscopy. They investigated the role of endothelial cell-derived exosomes in the proliferation, apoptosis, cell cycle, migration and invasion of I/R-injured SH-SY5Y cells. In addition, apoptosis-related molecules caspase-3, Bax and Bcl-2 were detected. RIP was determined to increase the number of exosomes and the expression levels of CD63, HSP70 and TSG101 in plasma, but not in brain hippocampal tissue. The size of exosomes released after I/R in HUVECs was similar to the size of exosomes released in rats subjected to RIP. Endothelial cell-derived exosomes partly suppressed the I/R-induced cell cycle arrest and apoptosis, and inhibited cell proliferation, migration and invasion in SH-SY5Y nerve cells. Endothelial cell-derived exosomes directly protect nerve cells against I/R injury, and are responsible for the protective role of RIP in I/R.

10 CFR 431.101 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... EQUIPMENT Commercial Water Heaters, Hot Water Supply Boilers and Unfired Hot Water Storage Tanks § 431.101 Purpose and scope. This subpart contains energy conservation requirements for certain commercial water heaters, hot water supply boilers and unfired hot water storage tanks, pursuant to Part C of Title III of...

Effects of Angle Variations in Suspension Push-up Exercise.

PubMed

Gulmez, Irfan

2017-04-01

Gulmez, I. Effects of angle variations in suspension push-up exercise. J Strength Cond Res 31(4): 1017-1023, 2017-This study aimed to determine and compare the amount of loads on the TRX Suspension Trainer (TRX) straps and ground reaction forces at 4 different angles during TRX push-ups. Twenty-eight male (mean age, 24.1 ± 2.9 years; height, 179.4 ± 8.0 m; weight, 78.8 ± 9.8 kg) physical education and sports university students participated in this study. The subjects were tested at TRX angles (0, 15, 30, 45°) during the TRX push-ups. Force data were recorded by a force platform and load cells integrated into the TRX straps. The results show that as the TRX angle was reduced, the load applied to the TRX straps increased and simultaneously the load measured by the force platform decreased. This was true for both the elbow joint changing from flexion to extension and vice versa. When the TRX angle was set at 0° and subjects' elbows were at extension during TRX push-up, 50.4% of the subjects' body weight, and when the elbows were at flexion, 75.3% of the body weight was registered by the sensors on the TRX straps. The results of this study can be used in the calculation of the training load and volume (resistance training programming) during TRX push-up exercises at varying angles.

Hanford Tank 241-C-103 Residual Waste Contaminant Release Models and Supporting Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cantrell, Kirk J.; Krupka, Kenneth M.; Deutsch, William J.

2008-01-15

This report tabulates data generated by laboratory characterization and testing of three samples collected from tank C-103. The data presented here will form the basis for a release model that will be developed for tank C-103. These release models are being developed to support the tank risk assessments performed by CH2M HILL Hanford Group, Inc. for DOE.

Methods for Heel Retrieval for Tanks C-101, C-102, and C-111 at the Hanford Site - 13064

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sams, T.L.; Kirch, N.W.; Reynolds, J.H.

The purpose of this paper is to evaluate the prospects of using bulk waste characteristics to determine the most appropriate heel retrieval technology. If the properties of hard to remove heels can be determined before bulk retrieval, then a heel retrieval technology can be selected before bulk retrieval is complete. This would save substantially on sampling costs and would allow the deployment of the heel retrieval technology immediately after bulk retrieval. The latter would also accelerate the heel removal schedule. A number of C-farm retrievals have been fully or partially completed at the time of this writing. Thus, there ismore » already substantial information on the success of different technologies and the composition of the heels. There is also substantial information on the waste types in each tank based on historical records. Therefore, this study will correlate the performance of technologies used so far and compare them to the known waste types in the tanks. This will be used to estimate the performance of future C Farm heel retrievals. An initial decision tree is developed and employed on tanks C-101, C-102, and C 111. An assumption of this study is that no additional characterization information would be available, before or after retrieval. Note that collecting additional information would substantially increase the probability of success. Deploying some in-situ testing technologies, such as a water lance or an in-situ Raman probe, might substantially increase the probability of successfully selecting the process conditions without having to take samples from the tanks for laboratory analysis. (authors)« less

Toxic chemical considerations for tank farm releases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Van Keuren, J.C.; Davis, J.S., Westinghouse Hanford

1996-08-01

This topical report contains technical information used to determine the accident consequences of releases of toxic chemical and gases for the Tank Farm Final Safety Analysis report (FSAR).It does not provide results for specific accident scenarios but does provide information for use in those calculations including chemicals to be considered, chemical concentrations, chemical limits and a method of summing the fractional contributions of each chemical. Tank farm composites evaluated were liquids and solids for double shell tanks, single shell tanks, all solids,all liquids, headspace gases, and 241-C-106 solids. Emergency response planning guidelines (ERPGs) were used as the limits.Where ERPGs weremore » not available for the chemicals of interest, surrogate ERPGs were developed. Revision 2 includes updated sample data, an executive summary, and some editorial revisions.« less

Results of Characterization and Retrieval Testing on Tank 241-C-109 Heel Solids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Callaway, William S.

Eight samples of heel solids from tank 241-C-109 were delivered to the 222-S Laboratory for characterization and dissolution testing. After being drained thoroughly, one-half to two-thirds of the solids were off-white to tan solids that, visually, were fairly evenly graded in size from coarse silt (30-60 μm) to medium pebbles (8-16 mm). The remaining solids were mostly strongly cemented aggregates ranging from coarse pebbles (16-32 mm) to fine cobbles (6-15 cm) in size. Solid phase characterization and chemical analysis indicated that the air-dry heel solids contained ≈58 wt% gibbsite [Al(OH){sub 3}] and ≈37 wt% natrophosphate [Na{sub 7}F(PO{sub 4}){sub 2}·19H{sub 2}O].more » The strongly cemented aggregates were mostly fine-grained gibbsite cemented with additional gibbsite. Dissolution testing was performed on two test samples. One set of tests was performed on large pieces of aggregate solids removed from the heel solids samples. The other set of dissolution tests was performed on a composite sample prepared from well-drained, air-dry heel solids that were crushed to pass a 1/4-in. sieve. The bulk density of the composite sample was 2.04 g/mL. The dissolution tests included water dissolution followed by caustic dissolution testing. In each step of the three-step water dissolution tests, a volume of water approximately equal to 3 times the initial volume of the test solids was added. In each step, the test samples were gently but thoroughly mixed for approximately 2 days at an average ambient temperature of 25 °C. The caustic dissolution tests began with the addition of sufficient 49.6 wt% NaOH to the water dissolution residues to provide ≈3.1 moles of OH for each mole of Al estimated to have been present in the starting composite sample and ≈2.6 moles of OH for each mole of Al potentially present in the starting aggregate sample. Metathesis of gibbsite to sodium aluminate was then allowed to proceed over 10 days of gentle mixing of the test samples

HANFORD DOUBLE SHELL TANK THERMAL AND SEISMIC PROJECT SEISMIC ANALYSIS IN SUPPORT OF INCREASED LIQUID LEVEL IN 241-AP TANK FARMS

DOE Office of Scientific and Technical Information (OSTI.GOV)

TC MACKEY; FG ABATT; MW RINKER

2009-01-14

The essential difference between Revision 1 and the original issue of this report is in the spring constants used to model the anchor bolt response for the anchor bolts that tie the steel dome of the primary tank to the concrete tank dome. Consequently, focus was placed on the changes in the anchor bolt responses, and a full reevaluation of all tank components was judged to be unnecessary. To confirm this judgement, primary tank stresses from the revised analysis of the BES-BEC case are compared to the original analysis and it was verified that the changes are small, as expected.

CHARACTERIZATION OF TANK 5F VERTICAL COOLING COIL LEACHATES FOR SELECT RADIONUCLIDES 2011

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oji, L.; Diprete, D.

2001-08-17

Two twenty-four inch samples of vertical sections of the cooling coils from Tank 5F, taken from Riser 1, were made available to SRNL by SRR for leaching and characterization of the leachates for select radionuclide trapped in the corrosion layer on the exterior of the cooling coils. One piece of cooling coil sample was obtained from a section of a vertical cooling coil located above the 45-inch elevation from the tank floor and the other also from a vertical section of a cooling coil located below the 45-inch elevation from the tank floor of Tank 5F. Analysis results from bothmore » cooling coils show that the predominant radionuclides contributing to the activity in both coils are strontium-90 and cesium-137. The activities for strontium-90 and cesium-137 in the Tank 5F vertical cooling coil located above the 45-inch elevation of the tank and designated as sample 5-R1-A45 averaged 1.34E-02 {+-} 1.12E-03 and 7.27E-04 {+-} 4.46E-05 Ci/ft{sup 2}, respectively, while the activities for the vertical cooling coil located below the 45-inch elevation of the tank and designated as sample 5-R1-B45 averaged 8.93E-03 {+-} 8.25E-04 for Sr-90 and 8.10E-04 {+-} 6.36E-05 Ci/ft{sup 2} for Cs-137. Other significant activity contributing radionuclides are americium-241 and europium-154/155. With the exception of the analysis result for Pu-241 in the 5-R1-A45 cooling coils samples, the target detection limits for the other radionuclides were met in both cooling coil samples. The detection limits for Pu-241 analyses result in coil sample 5-R1-A45 were not met consistently because of possible background changes during counting.« less

Residual waste from Hanford tanks 241-C-203 and 241-C-204. 1. Solids characterization.

PubMed

Krupka, Kenneth M; Schaef, Herbert T; Arey, Bruce W; Heald, Steve M; Deutsch, William I; Lindberg, Michael J; Cantrell, Kirk J

2006-06-15

Bulk X-ray diffraction (XRD), synchrotron X-ray microdiffraction (microXRD), and scanning electron microscopy/ energy-dispersive X-ray spectroscopy (SEM/EDS) were used to characterize solids in residual sludge from single-shell underground waste tanks C-203 and C-204 at the U.S. Department of Energy's Hanford Site in southeastern Washington state. Cejkaite [Na4(UO2)(CO3)3] was the dominant crystalline phase in the C-203 and C-204 sludges. This is one of the few occurrences of cejkaite reported in the literature and may be the first documented occurrence of this phase in radioactive wastes from DOE sites. Characterization of residual solids from water leach and selective extraction tests indicates that cejkaite has a high solubility and a rapid rate of dissolution in water at ambient temperature and that these sludges may also contain poorly crystalline Na2U207 [or clarkeite Na[(UO2)O(OH)](H2O)0-1] as well as nitratine (soda niter, NaNO3), goethite [alpha-FeO(OH)], and maghemite (gamma-Fe2O3). Results of the SEM/EDS analyses indicate that the C-204 sludge also contains a solid that lacks crystalline form and is composed of Na, Al, P, O, and possibly C. Other identified solids include Fe oxides that often also contain Cr and Ni and occur as individual particles, coatings on particles, and botryoidal aggregates; a porous-looking material (or an aggregate of submicrometer particles) that typically contain Al, Cr, Fe, Na, Ni, Si, U, P, O, and C; Si oxide (probably quartz); and Na-Al silicate(s). The latter two solids probably represent minerals from the Hanford sediment, which were introduced into the tank during prior sampling campaigns or other tank operation activities. The surfaces of some Fe-oxide particles in residual solids from the water leach and selective extraction tests appear to have preferential dissolution cavities. If these Fe oxides contain contaminants of concern, then the release of these contaminants into infiltrating water would be limited by the

View along road at "tank farm." From left to right: ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View along road at "tank farm." From left to right: T18, T10, T8, T5, with new rain shed (Building No. 241) in background. - Hawaii Volcanoes National Park Water Collection System, Hawaii Volcanoes National Park, Volcano, Hawaii County, HI

LABORATORY REPORT ON THE REMOVAL OF PERTECHNETATE FROM TANK 241-AN-105 SIMULANT USING PUROLITE A530E

DOE Office of Scientific and Technical Information (OSTI.GOV)

DUNCAN JB; HAGERTY KJ, MOORE WP; JOHNSON JM

2012-04-17

falls under the technetium management initiative and will provide data for those who will make decisions on the handling and disposition of technetium. To that end, the objective of this effort was to challenge Purolite{reg_sign} A530E against a double-shell tank (DST) simulant (tank 241-AN-105 or AN-105) spiked with pertechnetate (TcO{sub 4}{sup -}) to determine breakthrough of the lead column.« less

The Dwarf Nova SY Cancri and its Environs

NASA Astrophysics Data System (ADS)

Landolt, A. U.; Clem, J. L.

2018-06-01

Multicolor UBVRI photometry, collected intermittedly over a period of 22 years, is presented for the dwarf nova SY Cancri. Additional UBVRI photometry for a handful of sequence stars in the vicinity of SY Cancri is also presented.

Project W-320, 241-C-106 sluicing HVAC calculations, Volume 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bailey, J.W.

1998-08-07

This supporting document has been prepared to make the FDNW calculations for Project W-320, readily retrievable. The report contains the following calculations: Exhaust airflow sizing for Tank 241-C-106; Equipment sizing and selection recirculation fan; Sizing high efficiency mist eliminator; Sizing electric heating coil; Equipment sizing and selection of recirculation condenser; Chiller skid system sizing and selection; High efficiency metal filter shielding input and flushing frequency; and Exhaust skid stack sizing and fan sizing.

High-Precision Plutonium Isotopic Compositions Measured on Los Alamos National Laboratory’s General’s Tanks Samples: Bearing on Model Ages, Reactor Modelling, and Sources of Material. Further Discussion of Chronometry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spencer, Khalil J.; Rim, Jung Ho; Porterfield, Donivan R.

2015-06-29

In this study, we re-analyzed late-1940’s, Manhattan Project era Plutonium-rich sludge samples recovered from the ''General’s Tanks'' located within the nation’s oldest Plutonium processing facility, Technical Area 21. These samples were initially characterized by lower accuracy, and lower precision mass spectrometric techniques. We report here information that was previously not discernable: the two tanks contain isotopically distinct Pu not only for the major (i.e., 240Pu, 239Pu) but trace ( 238Pu , 241Pu, 242Pu) isotopes. Revised isotopics slightly changed the calculated 241Am- 241Pu model ages and interpretations.

Registration of ‘SY Clearstone 2CL’ wheat

USDA-ARS?s Scientific Manuscript database

‘SY Clearstone 2CL’ (Reg. No. CV-1094, PI 668090) hard red winter wheat (Triticum aestivum L.) was developed by the Montana Agricultural Experiment Station and released in September 2012 through a marketing agreement with Syngenta Seeds. SY Clearstone 2CL is a two-gene Clearfield backcross-derivativ...

Desulfurization of dibenzothiophene by Corynebacterium sp. strain SY1.

PubMed Central

Omori, T; Monna, L; Saiki, Y; Kodama, T

1992-01-01

Strain SY1, identified as a Corynebacterium sp., was isolated on the basis of the ability to utilize dibenzothiophene (DBT) as a sole source of sulfur. Strain SY1 could utilize a wide range of organic and inorganic sulfur compounds, such as DBT sulfone, dimethyl sulfide, dimethyl sulfoxide, dimethyl sulfone, CS2, FeS2, and even elemental sulfur. Strain SY1 metabolized DBT to dibenzothiophene-5-oxide, DBT sulfone, and 2-hydroxybiphenyl, which was subsequently nitrated to produce at least two different hydroxynitrobiphenyls during cultivation. These metabolites were separated by silica gel column chromatography and identified by nuclear magnetic resonance, UV, and mass spectral techniques. Resting cells of SY1 desulfurized toluenesulfonic acid and released sulfite anion. On the basis of these results, a new DBT degradation pathway is proposed. PMID:1575493

Complementation of Conjugation Functions of Streptomyces lividans Plasmid pIJ101 by the Related Streptomyces Plasmid pSB24.2

PubMed Central

Pettis, Gregg S.; Prakash, Shubha

1999-01-01

A database search revealed extensive sequence similarity between Streptomyces lividans plasmid pIJ101 and Streptomyces plasmid pSB24.2, which is a deletion derivative of Streptomyces cyanogenus plasmid pSB24.1. The high degree of relatedness between the two plasmids allowed the construction of a genetic map of pSB24.2, consisting of putative transfer and replication loci. Two pSB24.2 loci, namely, the cis-acting locus for transfer (clt) and the transfer-associated korB gene, were shown to be capable of complementing the pIJ101 clt and korB functions, respectively, a result that is consistent with the notion that pIJ101 and the parental plasmid pSB24.1 encode highly similar, if not identical, conjugation systems. PMID:10419972

75 FR 9638 - Safety Advisory Notice: Use of Composite Cargo Tanks Manufactured Under DOT Special Permits

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-03

.... PHMSA-2010-0046; Notice No. 10-1] Safety Advisory Notice: Use of Composite Cargo Tanks Manufactured... use composite cargo tank motor vehicles authorized under DOT special permits of the requirement to... for composite cargo tanks, such as fiber reinforced plastic (FRP) or glass fiber reinforced plastic...

Desulfurization of dibenzothiophene by Corynebacterium sp. strain SY1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Omori, Toshio; Monna, L.; Saiki, Yuko

1992-03-01

Strain SY1, identified as a Corynebacterium sp., was isolated on the basis of the ability to utilize dibenzothiophene (DBT) as a sole source of sulfur. Strain SY1 could utilize a wide range of organic and inorganic sulfur compounds, such as DBT sulfone, dimethyl sulfide, dimethyl sulfoxide, dimethyl sulfone, CS{sub 2}, FeS{sub 2}, and even elemental sulfur. Strain SY1 metabolized DBT to dibenzothiophene-5-oxide, DBT sulfone, and 2-hydroxybiphenyl, which was subsequently nitrated to produce at least two different hydroxynitrobiphenyls during cultivation. These metabolites were separated by silica gel column chromatography and identified by nuclear magnetic resonance, UV, and mass spectral techniques. Restingmore » cells of SY1 desulfurized toluenesulfonic acid and released sulfite anion. On the basis of these results, a new DBT degradation pathway is proposed.« less

Reanalysis of Plutonium and Americium-241 in the Tank 19F Closure Grab and Core Samples

DOE Office of Scientific and Technical Information (OSTI.GOV)

Swingle, R.F.

2003-02-11

Tank 19F is scheduled to be closed by March 2004. To close this tank, a characterization of the waste remaining in the tank was required to confirm the inventory of various species for input into groundwater transport models. This characterization has been developed by a combination of process knowledge, visual observation and sample analysis. The characterization samples were obtained by High Level Waste Division (HLWD) personnel and characterized by SRTC personnel.

Towards electrochromic devices having visible color switching using electronic push-push and push-pull cinnamaldehyde derivatives.

PubMed

Navarathne, Daminda; Skene, W G

2013-12-11

A series of symmetric and unsymmetric conjugated azomethines derived from cinnamaldehyde and 2,5-diaminothiophene-3,4-dicarboxylic acid diethyl ester were prepared. The optical, electrochemical, and spectroelectrochemical properties of the electronic push-pull and push-push triads were investigated. Their properties could be tuned contingent on the cinnamaldehyde's electron withdrawing and donating substituents. The push-push symmetric derivative exhibited positive solvatochromism with the absorbance spanning some 31 nm, depending on the solvent polarity. Solvent dependent spectroelectrochemistry was also found for the symmetric push-push azomethine. The color of the neutral state and radical cation spanned 215 nm. The most pronounced color transition of the purple colored material was found in dimethyl sulfoxide (DMSO), where the color bleached with electrochemical oxidation. This was a result of the absorbance shifting into the near infrared (NIR) and not from decomposition of the azomethine. Electrochromic devices with the azomethines possessing desired reversible oxidation and color changes in the visible were fabricated and tested to demonstrate the applicability of these azomethine triads in devices.

Project W-320, tank 241-C-106 sluicing acceptance for beneficial use

DOE Office of Scientific and Technical Information (OSTI.GOV)

BAILEY, J.W.

The purpose of this document is to identify the Project W-320 Chiller Documentation required to be turned over from the Projects Organization to Tank Farm Operations as part of the acceptance of the new equipment for beneficial use.

SyRoTek--Distance Teaching of Mobile Robotics

ERIC Educational Resources Information Center

Kulich, M.; Chudoba, J.; Kosnar, K.; Krajnik, T.; Faigl, J.; Preucil, L.

2013-01-01

E-learning is a modern and effective approach for training in various areas and at different levels of education. This paper gives an overview of SyRoTek, an e-learning platform for mobile robotics, artificial intelligence, control engineering, and related domains. SyRoTek provides remote access to a set of fully autonomous mobile robots placed in…

ECTA/DaSy Framework Self-Assessment Comparison Tool

ERIC Educational Resources Information Center

Center for IDEA Early Childhood Data Systems (DaSy), 2016

2016-01-01

The Self-Assessment Comparison (SAC) Tool is for state Part C and Section 619/Preschool programs to use to assess changes in the implementation of one or more components of the ECTA System Framework and/or subcomponenets of the DaSy Data System Framework. It is a companion to the ECTA/DaSy Framework Self-Assessment. Key features of the SAC are…

HOW OLD IS IT? - 241PU/241AM NUCLEAR FORENSIC CHRONOLOGY REFERENCE MATERIALS

PubMed Central

Fitzgerald, Ryan; Inn, Kenneth G.W.; Horgan, Christopher

2018-01-01

One material attribute for nuclear forensics is material age. 241Pu is almost always present in uranium- and plutonium-based nuclear weapons, which pose the greatest threat to our security. The in-growth of 241Am due to the decay of 241Pu provides an excellent chronometer of the material. A well-characterized 241Pu/241Am standard is needed to validate measurement capability, as a basis for between-laboratory comparability, and as material for verifying laboratory performance. This effort verifies the certification of a 38 year old 241Pu Standard Reference Material (SRM4340) through alpha-gamma anticoincidence counting, and also establishes the separation date to two weeks of the documented date. PMID:29720779

Progress in Cochlear Physiology after Békésy

PubMed Central

Guinan, John J.; Salt, Alec; Cheatham, Mary Ann

2012-01-01

In the fifty years since Békésy was awarded the Nobel Prize, cochlear physiology has blossomed. Many topics that are now current are things Békésy could not have imagined. In this review we start by describing progress in understanding the origin of cochlear gross potentials, particularly the cochlear microphonic, an area in which Békésy had extensive experience. We then review progress in areas of cochlear physiology that were mostly unknown to Békésy, including: (1) stereocilia mechano-electrical transduction, force production, and response amplification, (2) outer hair cell (OHC) somatic motility and its molecular basis in prestin, (3) cochlear amplification and related micromechanics, including the evidence that prestin is the main motor for cochlear amplification, (4) the influence of the tectorial membrane, (5) cochlear micromechanics and the mechanical drives to inner hair cell stereocilia, (6) otoacoustic emissions, and (7) olivocochlear efferents and their influence on cochlear physiology. We then return to a subject that Békésy knew well: cochlear fluids and standing currents, as well as our present understanding of energy dependence on the lateral wall of the cochlea. Finally, we touch on cochlear pathologies including noise damage and aging, with an emphasis on where the field might go in the future. PMID:22633944

Comparison of push-out bond strengths of Resilon with three different sealers.

PubMed

Stiegemeier, Danielle; Baumgartner, J Craig; Ferracane, Jack

2010-02-01

The purpose of this study was to evaluate the push-out bond strengths of different obturating materials. Forty single-rooted human extracted teeth were used in this study. The teeth were instrumented and irrigated by using 5.25% NaOCl, 15% ethylenediaminetetraacetic acid, and sterile water. The teeth were then filled with Resilon/RealSeal, Resilon/RealSeal SE, Resilon/MetaSeal , or gutta-percha/Kerr EWT sealer. The roots were then sectioned into 1-mm-thick slices and subjected to vertical loading to displace the obturating material toward the coronal side of the slice. The bond strength was then calculated and subjected to statistical analysis. Slices were examined by using a stereomicroscope at 30x to determine the mode of failure. The mean push-out bond strengths were as follows: Resilon/RealSeal, 1.45 +/- 0.99 MPa; RealSeal SE, 0.88 +/- 0.49 MPa; Resilon/MetaSeal, 2.41 +/- 1.7 MPa; and gutta-percha/Kerr EWT sealer, 2.32 +/- 0.74 MPa. The push-out bond strengths of Resilon/MetaSeal and gutta-percha/Kerr EWT were significantly (P < .05) higher than either Resilon/RealSeal or Resilon/RealSeal SE. Resilon/MetaSeal and gutta-percha/Kerr EWT did not differ significantly. Copyright 2010 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Using Photogrammetry to Estimate Tank Waste Volumes from Video

DOE Office of Scientific and Technical Information (OSTI.GOV)

Field, Jim G.

Washington River Protection Solutions (WRPS) contracted with HiLine Engineering & Fabrication, Inc. to assess the accuracy of photogrammetry tools as compared to video Camera/CAD Modeling System (CCMS) estimates. This test report documents the results of using photogrammetry to estimate the volume of waste in tank 241-C-I04 from post-retrieval videos and results using photogrammetry to estimate the volume of waste piles in the CCMS test video.

Final Report One-Twelfth-Scale Mixing Experiments to Characterize Double-Shell Tank Slurry Uniformity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bamberger, Judith A.; Liljegren, Lucia M.; Enderlin, Carl W.

The objectives of these 1/12-scale scoping experiments were to: Determine which of the dimensionless parameters discussed in Bamberger and Liljegren (1994) affect the maximum concentration that can be suspended during jet mixer pump operation in the full-scale double-shell tanks; Develop empirical correlations to predict the nozzle velocity required for jet mixer pumps to suspend the contents of full-scale double-shell tanks; Apply the models to predict the nozzle velocity required to suspend the contents of Tank 241 AZ-101; Obtain experimental concentration data to compare with the TEMPEST( )(Trent and Eyler 1989) computational modeling predictions to guide further code development; Analyze themore » effects of changing nozzle diameter on exit velocity (U0) and U0D0 (the product of the exit velocity and nozzle diameter) required to suspend the contents of a tank. The scoping study experimentally evaluated uniformity in a 1/12-scale experiment varying the Reynolds number, Froude number, and gravitational settling parameter space. The initial matrix specified only tests at 100% U0D0 and 25% U0D0. After initial tests were conducted with small diameter, low viscosity simulant this matrix was revised to allow evaluation of a broader range of U0D0s. The revised matrix included full factorial test between 100% and 50% U0D0 and two half-factorial tests at 75% and 25% U0D0. Adding points at 75% U0D0 and 50% U0D0 allowed evaluation curvature. Eliminating points at 25% U0D0 decreased the testing time by several weeks. Test conditions were achieved by varying the simulant viscosity, the mean particle size, and the jet nozzle exit velocity. Concentration measurements at sampling locations throughout the tank were used to assess the degree of uniformity achieved during each test. Concentration data was obtained using a real time ultrasonic attenuation probe and discrete batch samples. The undissolved solids concentration at these locations was analyzed to determine whether

24 CFR 241.1005 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

...; § 241.1(k)—Energy conserving improvements; § 241.1(1)—Solar energy system. (b) As used in subpart E of...-Eligibility Requirements § 241.1005 Definitions. (a) All of the definitions of § 241.1 apply to equity and...

Environmental Assessment: Waste Tank Safety Program, Hanford Site, Richland, Washington

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-02-01

The US Department of Energy (DOE) needs to take action in the near-term, to accelerate resolution of waste tank safety issues at the Hanford Site near the City of Richland, Washington, and reduce the risks associated with operations and management of the waste tanks. The DOE has conducted nuclear waste management operations at the Hanford Site for nearly 50 years. Operations have included storage of high-level nuclear waste in 177 underground storage tanks (UST), both in single-shell tank (SST) and double-shell tank configurations. Many of the tanks, and the equipment needed to operate them, are deteriorated. Sixty-seven SSTs are presumedmore » to have leaked a total approximately 3,800,000 liters (1 million gallons) of radioactive waste to the soil. Safety issues associated with the waste have been identified, and include (1) flammable gas generation and episodic release; (2) ferrocyanide-containing wastes; (3) a floating organic solvent layer in Tank 241-C-103; (4) nuclear criticality; (5) toxic vapors; (6) infrastructure upgrades; and (7) interim stabilization of SSTs. Initial actions have been taken in all of these areas; however, much work remains before a full understanding of the tank waste behavior is achieved. The DOE needs to accelerate the resolution of tank safety concerns to reduce the risk of an unanticipated radioactive or chemical release to the environment, while continuing to manage the wastes safely.« less

49 CFR 172.328 - Cargo tanks.

Code of Federal Regulations, 2010 CFR

2010-10-01

... containing liquefied petroleum gas (LPG) that is unodorized as authorized in § 173.315(b)(1) unless it is... markings: Gases. Except for certain nurse tanks which must be marked as specified in § 173.315(m) of this... specified for the gas in the § 172.101 table; or (2) An appropriate common name for the material (e.g...

33 CFR 90.3 - Pushing vessel and vessel being pushed: Composite unit.

Code of Federal Regulations, 2010 CFR

2010-07-01

... pushed: Composite unit. 90.3 Section 90.3 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... vessel being pushed: Composite unit. Rule 24(b) of the Inland Rules states that when a pushing vessel and a vessel being pushed ahead are rigidly connected in a composite unit, they are regarded as a power...

33 CFR 82.3 - Pushing vessel and vessel being pushed: Composite unit.

Code of Federal Regulations, 2010 CFR

2010-07-01

... pushed: Composite unit. 82.3 Section 82.3 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... vessel being pushed: Composite unit. Rule 24(b) of the 72 COLREGS states that when a pushing vessel and a vessel being pushed ahead are rigidly connected in a composite unit, they are regarded as a power-driven...

Human push capability.

PubMed

Barnett, Ralph L; Liber, Theodore

2006-02-22

Use of unassisted human push capability arises from time to time in the areas of crowd and animal control, the security of locked doors, the integrity of railings, the removal of tree stumps and entrenched vehicles, the manoeuvering of furniture, and athletic pursuits such as US football or wrestling. Depending on the scenario, human push capability involves strength, weight, weight distribution, push angle, footwear/floor friction, and the friction between the upper body and the pushed object. Simple models are used to establish the relationships among these factors.

Considerations for the use of SH-SY5Y neuroblastoma cells in neurobiology.

PubMed

Kovalevich, Jane; Langford, Dianne

2013-01-01

The use of primary mammalian neurons derived from embryonic central nervous system tissue is limited by the fact that once terminally differentiated into mature neurons, the cells can no longer be propagated. Transformed neuronal-like cell lines can be used in vitro to overcome this limitation. However, several caveats exist when utilizing cells derived from malignant tumors. In this context, the popular SH-SY5Y neuroblastoma cell line and its use in in vitro systems is described. Originally derived from a metastatic bone tumor biopsy, SH-SY5Y (ATCC(®) CRL-2266™) cells are a subline of the parental line SK-N-SH (ATCC(®) HTB-11™). SK-N-SH were subcloned three times; first to SH-SY, then to SH-SY5, and finally to SH-SY5Y. SH-SY5Y were deposited to the ATCC(®) in 1970 by June L. Biedler.Three important characteristics of SH-SY5Y cells should be considered when using these cells in in vitro studies. First, cultures include both adherent and floating cells, both types of which are viable. Few studies address the biological significance of the adherent versus floating phenotypes, but most reported studies utilize adherent populations and discard the floating cells during media changes. Second, early studies by Biedler's group indicated that the parental differentiated SK-N-SH cells contained two morphologically distinct phenotypes: neuroblast-like cells and epithelial-like cells (Ross et al., J Nat Cancer Inst 71:741-747, 1983). These two phenotypes may correspond to the "N" and "S" types described in later studies in SH-SY5Y by Encinas et al. (J Neurochem 75:991-1003, 2000). Cells with neuroblast-like morphology are positive for tyrosine hydroxylase (TH) and dopamine-β-hydroxylase characteristic of catecholaminergic neurons, whereas the epithelial-like counterpart cells lacked these enzymatic activities (Ross et al., J Nat Cancer Inst 71:741-747, 1983). Third, SH-SY5Y cells can be differentiated to a more mature neuron-like phenotype that is characterized by

Nuclear Data Sheets for A=241

DOE PAGES

Nesaraja, Caroline D.

2015-11-27

This paper presents available information pertaining to the nuclear structure of ground and excited states for all known nuclei with mass numbers A=24, which have been compiled and evaluated. The adopted level and decay schemes, as well as the detailed nuclear properties and configuration assignments based on experimental data are presented for these nuclides. When there are insufficient data, expected values from systematics of nuclear properties or/and theoretical calculations are quoted. Unexpected or discrepant experimental results are also noted. A summary and compilation of the discovery of various isotopes in this mass region is given in 2013Fr02 ( 241Np, 241Pu,more » 241Am, 241Cm, 241Bk, and 241Cf), 2011Me01 (241Es), and 2013Th02 ( 241Fm).« less

91. REFRIGERANT CONDENSER TANKS IN NORTHEAST CORNER OF MECHANICAL EQUIPMENT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

91. REFRIGERANT CONDENSER TANKS IN NORTHEAST CORNER OF MECHANICAL EQUIPMENT ROOM (101), LSB (BLDG. 770). PREFILTERS AND PRESSURE CONTROLS IN CENTER OF PHOTOGRAPH. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

ICPP tank farm closure study. Volume 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spaulding, B.C.; Gavalya, R.A.; Dahlmeir, M.M.

1998-02-01

The disposition of INEEL radioactive wastes is now under a Settlement Agreement between the DOE and the State of Idaho. The Settlement Agreement requires that existing liquid sodium bearing waste (SBW), and other liquid waste inventories be treated by December 31, 2012. This agreement also requires that all HLW, including calcined waste, be disposed or made road ready to ship from the INEEL by 2035. Sodium bearing waste (SBW) is produced from decontamination operations and HLW from reprocessing of SNF. SBW and HLW are radioactive and hazardous mixed waste; the radioactive constituents are regulated by DOE and the hazardous constituentsmore » are regulated by the Resource Conservation and Recovery Act (RCRA). Calcined waste, a dry granular material, is produced in the New Waste Calcining Facility (NWCF). Two primary waste tank storage locations exist at the ICPP: Tank Farm Facility (TFF) and the Calcined Solids Storage Facility (CSSF). The TFF has the following underground storage tanks: four 18,400-gallon tanks (WM 100-102, WL 101); four 30,000-gallon tanks (WM 103-106); and eleven 300,000+ gallon tanks. This includes nine 300,000-gallon tanks (WM 182-190) and two 318,000 gallon tanks (WM 180-181). This study analyzes the closure and subsequent use of the eleven 300,000+ gallon tanks. The 18,400 and 30,000-gallon tanks were not included in the work scope and will be closed as a separate activity. This study was conducted to support the HLW Environmental Impact Statement (EIS) waste separations options and addresses closure of the 300,000-gallon liquid waste storage tanks and subsequent tank void uses. A figure provides a diagram estimating how the TFF could be used as part of the separations options. Other possible TFF uses are also discussed in this study.« less

Views of the external tank as it falls away from Discovery

NASA Image and Video Library

1995-07-13

STS070-303-007 (13 JULY 1995) --- The external fuel tank (ET) for STS-70 is photographed just after falling away from the space shuttle Discovery en route to the 101st human-tended United States space flight.

ETR BASEMENT, TRA642, INTERIOR. BASEMENT. CUBICLE INTERIOR (SEE PHOTOS ID33G101 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

ETR BASEMENT, TRA-642, INTERIOR. BASEMENT. CUBICLE INTERIOR (SEE PHOTOS ID-33-G-101 AND ID-33-G-102) WITH TANK AND SODIUM-RELATED APPARATUS. CAMERA STANDS BEFORE ROLL-UP DOOR SHOWN IN PHOTO ID-33-G-101. INL NEGATIVE NO. HD24-3-3. Mike Crane, Photographer, 11/2000 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

48 CFR 241.201 - Policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Policy. 241.201 Section 241.201 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF UTILITY SERVICES Acquiring Utility Services 241...

Considerations for the Use of SH-SY5Y Neuroblastoma Cells in Neurobiology

PubMed Central

Kovalevich, Jane; Langford, Dianne

2016-01-01

The use of primary mammalian neurons derived from embryonic central nervous system tissue is limited by the fact that once terminally differentiated into mature neurons, the cells can no longer be propagated. Transformed neuronal-like cell lines can be used in vitro to overcome this limitation. However, several caveats exist when utilizing cells derived from malignant tumors. In this context, the popular SH-SY5Y neuroblastoma cell line and its use in in vitro systems is described. Originally derived from a metastatic bone tumor biopsy, SH-SY5Y (ATCC® CRL-2266™) cells are a subline of the parental line SK-N-SH (ATCC® HTB-11™). SK-N-SH were subcloned three times; first to SH-SY, then to SH-SY5, and finally to SH-SY5Y. SH-SY5Y were deposited to the ATCC® in 1970 by June L. Biedler. Three important characteristics of SH-SY5Y cells should be considered when using these cells in in vitro studies. First, cultures include both adherent and floating cells, both types of which are viable. Few studies address the biological significance of the adherent versus floating phenotypes, but most reported studies utilize adherent populations and discard the floating cells during media changes. Second, early studies by Biedler’s group indicated that the parental differentiated SK-N-SH cells contained two morphologically distinct phenotypes: neuroblast-like cells and epithelial-like cells (Ross et al., J Nat Cancer Inst 71:741–747, 1983). These two phenotypes may correspond to the “N” and “S” types described in later studies in SH-SY5Y by Encinas et al. (J Neurochem 75:991–1003, 2000). Cells with neuroblast-like morphology are positive for tyrosine hydroxylase (TH) and dopamine-β-hydroxylase characteristic of catecholaminergic neurons, whereas the epithelial-like counterpart cells lacked these enzymatic activities (Ross et al., J Nat Cancer Inst 71:741–747, 1983). Third, SH-SY5Y cells can be differentiated to a more mature neuron-like phenotype that is

47 CFR 87.241 - Frequencies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false Frequencies. 87.241 Section 87.241 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AVIATION SERVICES Aeronautical Multicom Stations § 87.241 Frequencies. (a) 121.500 MHz: emergency and distress only; (b) 122.850...

46 CFR 169.241 - Machinery.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Machinery. 169.241 Section 169.241 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Inspection and Certification Inspections § 169.241 Machinery. (a) At each inspection for certification and periodic inspection...

46 CFR 169.241 - Machinery.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 7 2011-10-01 2011-10-01 false Machinery. 169.241 Section 169.241 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Inspection and Certification Inspections § 169.241 Machinery. (a) At each inspection for certification and periodic inspection...

7 CFR 1220.241 - Reports.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false Reports. 1220.241 Section 1220.241 Agriculture... CONSUMER INFORMATION Soybean Promotion and Research Order Reports, Books, and Records § 1220.241 Reports... to report to the Board periodically such information as may be required by the regulations...

7 CFR 1220.241 - Reports.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Reports. 1220.241 Section 1220.241 Agriculture... CONSUMER INFORMATION Soybean Promotion and Research Order Reports, Books, and Records § 1220.241 Reports... to report to the Board periodically such information as may be required by the regulations...

42 CFR 24.1 - Establishment.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Establishment. 24.1 Section 24.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.1 Establishment. There is established in the Public Health Service (PHS) a Senior Biomedical...

42 CFR 24.1 - Establishment.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Establishment. 24.1 Section 24.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.1 Establishment. There is established in the Public Health Service (PHS) a Senior Biomedical...

42 CFR 24.1 - Establishment.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Establishment. 24.1 Section 24.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.1 Establishment. There is established in the Public Health Service (PHS) a Senior Biomedical...

42 CFR 24.1 - Establishment.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Establishment. 24.1 Section 24.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.1 Establishment. There is established in the Public Health Service (PHS) a Senior Biomedical...

SyMRI of the Brain

PubMed Central

Hagiwara, Akifumi; Warntjes, Marcel; Hori, Masaaki; Andica, Christina; Nakazawa, Misaki; Kumamaru, Kanako Kunishima; Abe, Osamu; Aoki, Shigeki

2017-01-01

Abstract Conventional magnetic resonance images are usually evaluated using the image signal contrast between tissues and not based on their absolute signal intensities. Quantification of tissue parameters, such as relaxation rates and proton density, would provide an absolute scale; however, these methods have mainly been performed in a research setting. The development of rapid quantification, with scan times in the order of 6 minutes for full head coverage, has provided the prerequisites for clinical use. The aim of this review article was to introduce a specific quantification method and synthesis of contrast-weighted images based on the acquired absolute values, and to present automatic segmentation of brain tissues and measurement of myelin based on the quantitative values, along with application of these techniques to various brain diseases. The entire technique is referred to as “SyMRI” in this review. SyMRI has shown promising results in previous studies when used for multiple sclerosis, brain metastases, Sturge-Weber syndrome, idiopathic normal pressure hydrocephalus, meningitis, and postmortem imaging. PMID:28257339

Cytotoxicity induced by cypermethrin in Human Neuroblastoma Cell Line SH-SY5Y.

PubMed

Raszewski, Grzegorz; Lemieszek, Marta Kinga; Łukawski, Krzysztof

2016-01-01

The purpose of this study was to evaluate the cytotoxic potential of Cypermethrin (CM) on cultured human Neuroblastoma SH-SY5Y cells. SH-SY5Y cells were treated with CM at 0-200µM for 24, 48, and 72 h, in vitro. It was found that CM induced the cell death of Neuroblastoma cells in a dose- and time-dependent manner, as shown by LDH assays. Next, some aspects of the process of cell death triggered by CM in the human SH-SY5Y cell line were investigated. It was revealed that the pan-caspase inhibitor Q-VD-OPh, sensitizes SH-SY5Y cells to necroptosis caused by CM. Furthermore, signal transduction inhibitors PD98059, SL-327, SB202190, SP600125 failed to attenuate the effect of the pesticide. Finally, it was shown that inhibition of TNF-a by Pomalidomide (PLD) caused statistically significant reduction in CM-induced cytotoxicity. Overall, the data obtained suggest that CM induces neurotoxicity in SH-SY5Y cells by necroptosis.

15 CFR 904.241 - Depositions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Depositions. 904.241 Section 904.241... and Appeal Procedures Discovery § 904.241 Depositions. (a) Notice. If a motion for deposition is granted, and unless otherwise ordered by the Judge, the party taking the deposition of any person must...

15 CFR 904.241 - Depositions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Depositions. 904.241 Section 904.241... and Appeal Procedures Discovery § 904.241 Depositions. (a) Notice. If a motion for deposition is granted, and unless otherwise ordered by the Judge, the party taking the deposition of any person must...

33 CFR 241.3 - References.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Information Services, 5285 Port Royal Road, Springfield, VA 22161. References (a), (b) and (c) may be reviewed... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false References. 241.3 Section 241.3... CONTROL COST-SHARING REQUIREMENTS UNDER THE ABILITY TO PAY PROVISION § 241.3 References. References cited...

Spatial analysis of plutonium-239 + 240 and Americium-241 in soils around Rocky Flats, Colorado

DOE Office of Scientific and Technical Information (OSTI.GOV)

Litaor, M.I.

1995-05-01

Plutonium and american contamination of soils around Rocky Flats, Colorado resulted from past outdoor storage practices. Four previous studies produce four different Pu isopleth maps. Spatial estimation techniques were not used in the construction of these maps and were also based on an extremely small number of soil samples. The purpose of this study was to elucidate the magnitude of Pu-239 + 240 and Am-241 dispersion in the soil environment east of Rocky Flats using robust spatial estimation techniques. Soils were sampled from 118 plots of 1.01 and 4.05 ha by compositing 25 evenly spaced samples in each plot frommore » the top 0.64 cm. Plutonium-239 + 240 activity ranged from 1.85 to 53 560 Bq/kg with a mean of 1924 Bq/kg and a standard deviation of 6327 Bq/kg. Americium-241 activity ranged from 0.18 to 9990 Bq/kg with a mean of 321 Bq/kg and a standard deviation of 1143 Bq/kg. Geostatistical techniques were used to model the spatial dependency and construct isopleth maps showing Pu-239 + 240 and Am-241 distribution. The isopleth configuration was consistent with the hypothesis that the dominant dispersal mechanism of Pu-239 + 240 was wind dispersion from west to east. The Pu-239 + 240 isopleth map proposed to this study differed significantly in the direction and distance of dispersal from the previously published maps. This ispleth map as well as the Am-241 map should be used as the primary data for future risk assessment associated with public exposure to Pu-239 + 240 and Am-241. 37 refs., 7 figs., 2 tabs.« less

Hysterosalpingo-contrast-sonography (HyCoSy) in the assessment of tubal patency in endometriosis patients.

PubMed

Moro, Francesca; Tropea, Anna; Selvaggi, Luigi; Scarinci, Elisa; Lanzone, Antonio; Apa, Rosanna

2015-03-01

Tubal patency in women with endometriosis has traditionally been evaluated by laparoscopy. The aim of this study was to investigate the accuracy of hysterosalpingo-contrast-sonography (HyCoSy) in the assessment of tubal patency in these women. A retrospective study was conducted at Physiopathology of Human Reproduction Unit. Infertile women who underwent HyCoSy and then a laparoscopy (dye test) within 6 months from the HyCoSy were included. Tubal patency was assessed by HyCoSy and the findings were compared with the results of laparoscopy, which was considered the gold standard for assessment of tubal patency. Sensitivity, specificity, positive and negative predictive values (PPV, NPV) and positive and negative likelihood ratios (Lh+, Lh-) were calculated including the 95% confidence interval (CI). A total of 1452 women underwent HyCoSy and 126 of them received a laparoscopy within 6 months from the HyCoSy. Of the 126 women, 42 (33.3%) had a diagnosis of pelvic endometriosis and 84 (66.7%) had no endometriosis. In the endometriosis population, HyCoSy showed a sensitivity, specificity, PPV, NPV, Lh+ and Lh- of 85% (95% CI 62-96), 93% (95% CI 82-97), 81% (95% CI 58-94), 94% (95% CI 84-98), 12.6 (95% CI 4.8-33) and 0.15 (95% CI 0.05-0.4) respectively. In the non-endometriosis group, HyCoSy showed a sensitivity, specificity, PPV, NPV, LR+ and LR- of 85% (95% CI 65-95), 93% (95% CI 87-96), 71% (95% CI 53-85), 97% (95% CI 92-99), 13.2 (95% CI 6.9-25) and 0.15 (95% CI 0.06-0.3) respectively. The diagnostic accuracy of HyCoSy was 91% in the endometriosis group and 92% in the non-endometriosis patients. HyCoSy showed high accuracy in evaluating tubal patency in infertile non-endometriosis women and in those affected by endometriosis. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

HANFORD DOUBLE SHELL TANK (DST) THERMAL & SEISMIC PROJECT SEISMIC ANALYSIS IN SUPPORT OF INCREASED LIQUID LEVEL IN 241-AP TANK FARMS

DOE Office of Scientific and Technical Information (OSTI.GOV)

MACKEY TC; ABBOTT FG; CARPENTER BG

2007-02-16

The overall scope of the project is to complete an up-to-date comprehensive analysis of record of the DST System at Hanford. The "Double-Shell Tank (DST) Integrity Project - DST Thermal and Seismic Project" is in support of Tri-Party Agreement Milestone M-48-14.

Cadmium inhibits neurite outgrowth in differentiating human SH-SY5Y neuroblastoma cells.

PubMed

Pak, Eun Joo; Son, Gi Dong; Yoo, Byung Sun

2014-01-01

Cadmium, a highly ubiquitous heavy metal, is well known to induce neurotoxicity. However, the underlying mechanism of cadmium-mediated neurotoxicity remains unclear. We have studied cadmium inhibition of neurite outgrowth using human SH-SY5Y neuroblastoma cells induced to differentiate by all-trans-retinoic acid (RA). Cadmium, at a concentration of 3 μmol/L, had no significant effect on the viability of differentiating SH-SY5Y cells. However, the neurite outgrowth of the differentiating SH-SY5Y cells 48 hours after cadmium treatment (1-3 μmol/L cadmium) was significantly inhibited in a dose-dependent manner. Treatment of RA-stimulated differentiating SH-SY5Y cells with 1 to 3 μmol/L cadmium resulted in decreased level of cross-reactivities with 43-kDa growth-associated protein (GAP-43) in a dose-dependent manner. The reactive oxygen species (ROS) scavenger, NAC (N-acetyl-l-cysteine), recovered the expression of GAP-43 in cadmium-treated cells. The results indicate that cadmium is able to inhibit neurite outgrowth of differentiating SH-SY5Y cells and that this effect might result from ROS generation by cadmium. © The Author(s) 2014.

Isolation and characterization of a plant growth-promoting rhizobacterium, Serratia sp. SY5.

PubMed

Koo, So-Yeon; Cho, Kyung-Suk

2009-11-01

The role of plant growth-promoting rhizobacteria (PGPR) in the phytoremediation of heavy-metal-contaminated soils is important in overcoming its limitations for field application. A plant growth-promoting rhizobacterium, Serratia sp. SY5, was isolated from the rhizoplane of barnyard grass (Echinochloa crus-galli) grown in petroleum and heavy-metal-contaminated soil. This isolate has shown capacities for indole acetic acid production and siderophores synthesis. Compared with a non-inoculated control, the radicular root growth of Zea mays seedlings inoculated with SY5 can be increased by 27- or 15.4-fold in the presence of 15 mg-Cd/l or 15 mg-Cu/l, respectively. The results from hydroponic cultures showed that inoculation of Serratia sp. SY5 had a favorable influence on the initial shoot growth and biomass of Zea mays under noncontaminated conditions. However, under Cd-contaminated conditions, the inoculation of SY5 significantly increased the root biomass of Zea mays. These results indicate that Serratia sp. SY5 can serve as a promising microbial inoculant for increased plant growth in heavy-metal-contaminated soils to improve the phytoremediation efficiency.

A new method to effectively and rapidly generate neurons from SH-SY5Y cells.

PubMed

Yang, HongNa; Wang, Jing; Sun, JinHua; Liu, XiaoDun; Duan, Wei-Ming; Qu, TingYu

2016-01-01

It is well known that neurons differentiated from SH-SY5Y cells can serve as cell models for neuroscience research; i.e., neurotoxicity and tolerance to morphine in vitro. To differentiate SH-SY5Y cells into neurons, RA (retinoic acid) is commonly used to produce the inductive effect. However, the percentage of neuronal cells produced from SH-SY5Y cells is low, either from the use of RA treatment alone or from the combined application of RA and other chemicals. In the current study, we used CM-hNSCs (conditioned medium of human neural stem cells) as the combinational inducer with RA to prompt neuronal differentiation of SH-SY5Y cells. We found that neuronal differentiation was improved and that neurons were greatly increased in the differentiated SH-SY5Y cells using a combined treatment of CM-hNSCs and RA compared to RA treatment alone. The neuronal percentage was higher than 80% (about 88%) on the 3rd day and about 91% on the 7th day examined after a combined treatment with CM-hNSCs and RA. Cell maturation and neurite growth of these neuronal cells were also improved. In addition, the use of CM-hNSCs inhibited the apoptosis of RA-treated SH-SY5Y cells in culture. We are the first to report the use of CM-hNSCs in combination with RA to induce neuronal differentiation of RA-treated SH-SY5Y cells. Our method can rapidly and effectively promote the neuronal production of SH-SY5Y cells in culture conditions. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Comb-push Ultrasound Shear Elastography (CUSE) with Various Ultrasound Push Beams

PubMed Central

Song, Pengfei; Urban, Matthew W.; Manduca, Armando; Zhao, Heng; Greenleaf, James F.; Chen, Shigao

2013-01-01

Comb-push Ultrasound Shear Elastography (CUSE) has recently been shown to be a fast and accurate two-dimensional (2D) elasticity imaging technique that can provide a full field-of- view (FOV) shear wave speed map with only one rapid data acquisition. The initial version of CUSE was termed U-CUSE because unfocused ultrasound push beams were used. In this paper, we present two new versions of CUSE – Focused CUSE (F-CUSE) and Marching CUSE (M-CUSE), which use focused ultrasound push beams to improve acoustic radiation force penetration and produce stronger shear waves in deep tissues (e.g. kidney and liver). F-CUSE divides transducer elements into several subgroups which transmit multiple focused ultrasound beams simultaneously. M-CUSE uses more elements for each focused push beam and laterally marches the push beams. Both F-CUSE and M-CUSE can generate comb-shaped shear wave fields that have shear wave motion at each imaging pixel location so that a full FOV 2D shear wave speed map can be reconstructed with only one data acquisition. Homogeneous phantom experiments showed that U-CUSE, F-CUSE and M-CUSE can all produce smooth shear wave speed maps with accurate shear wave speed estimates. An inclusion phantom experiment showed that all CUSE methods could provide good contrast between the inclusion and background with sharp boundaries while F-CUSE and M-CUSE require shorter push durations to achieve shear wave speed maps with comparable SNR to U-CUSE. A more challenging inclusion phantom experiment with a very stiff and deep inclusion shows that better shear wave penetration could be gained by using F-CUSE and M-CUSE. Finally, a shallow inclusion experiment showed that good preservations of inclusion shapes could be achieved by both U-CUSE and F-CUSE in the near field. Safety measurements showed that all safety parameters are below FDA regulatory limits for all CUSE methods. These promising results suggest that, using various push beams, CUSE is capable of

Comb-push ultrasound shear elastography (CUSE) with various ultrasound push beams.

PubMed

Song, Pengfei; Urban, Matthew W; Manduca, Armando; Zhao, Heng; Greenleaf, James F; Chen, Shigao

2013-08-01

Comb-push ultrasound shear elastography (CUSE) has recently been shown to be a fast and accurate 2-D elasticity imaging technique that can provide a full field-of-view (FOV) shear wave speed map with only one rapid data acquisition. The initial version of CUSE was termed U-CUSE because unfocused ultrasound push beams were used. In this paper, we present two new versions of CUSE-focused CUSE (F-CUSE) and marching CUSE (M-CUSE), which use focused ultrasound push beams to improve acoustic radiation force penetration and produce stronger shear waves in deep tissues (e.g., kidney and liver). F-CUSE divides transducer elements into several subgroups which transmit multiple focused ultrasound beams simultaneously. M-CUSE uses more elements for each focused push beam and laterally marches the push beams. Both F-CUSE and M-CUSE can generate comb-shaped shear wave fields that have shear wave motion at each imaging pixel location so that a full FOV 2-D shear wave speed map can be reconstructed with only one data acquisition. Homogeneous phantom experiments showed that U-CUSE, F-CUSE, and M-CUSE can all produce smooth shear wave speed maps with accurate shear wave speed estimates. An inclusion phantom experiment showed that all CUSE methods could provide good contrast between the inclusion and background with sharp boundaries while F-CUSE and M-CUSE require shorter push durations to achieve shear wave speed maps with comparable SNR to U-CUSE. A more challenging inclusion phantom experiment with a very stiff and deep inclusion shows that better shear wave penetration could be gained by using F-CUSE and M-CUSE. Finally, a shallow inclusion experiment showed that good preservations of inclusion shapes could be achieved by both U-CUSE and F-CUSE in the near field. Safety measurements showed that all safety parameters are below FDA regulatory limits for all CUSE methods. These promising results suggest that, using various push beams, CUSE is capable of reconstructing a 2-D full FOV

40 CFR 436.241 - Specialized definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 30 2011-07-01 2011-07-01 false Specialized definitions. 436.241 Section 436.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS MINERAL MINING AND PROCESSING POINT SOURCE CATEGORY Diatomite Subcategory § 436.241...

40 CFR 436.241 - Specialized definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Specialized definitions. 436.241 Section 436.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS MINERAL MINING AND PROCESSING POINT SOURCE CATEGORY Diatomite Subcategory § 436.241...

40 CFR 98.241 - Reporting threshold.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Reporting threshold. 98.241 Section 98.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petrochemical Production § 98.241 Reporting threshold. You must report...

40 CFR 98.241 - Reporting threshold.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Reporting threshold. 98.241 Section 98.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petrochemical Production § 98.241 Reporting threshold. You must report...

[Determination of americium-241 in urine].

PubMed

Shvydko, N S; Mikhaĭlova, O A; Popov, D K

1988-01-01

A technique has been developed for the determination of americium 241 in urine by a radiochemical purification of the nuclide from uranium (upon co-precipitation of americium 241 with calcium and lanthanum), plutonium, thorium, and polonium 210 (upon co-precipitation of these radionuclides with zirconium iodate). alpha-Radioactivity was measured either in a thick layer of the americium 241 precipitate with a nonisotope carrier or in thin-layer preparations after electrolytic precipitation of americium 241 on a cathode.

32 CFR 241.11 - Numerical limitation.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 2 2011-07-01 2011-07-01 false Numerical limitation. 241.11 Section 241.11 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.11 Numerical...

32 CFR 241.11 - Numerical limitation.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Numerical limitation. 241.11 Section 241.11 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.11 Numerical...

32 CFR 241.11 - Numerical limitation.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 2 2013-07-01 2013-07-01 false Numerical limitation. 241.11 Section 241.11 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.11 Numerical...

Deep Sludge Gas Release Event Analytical Evaluation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sams, Terry L.

2013-08-15

technical report is to (1) present and discuss current understandings of gas retention and release mechanisms for deep sludge in U.S. Department of Energy (DOE) complex waste storage tanks; and (2) to identify viable methods/criteria for demonstrating safety relative to deep sludge gas release events (DSGRE) in the near term to support the Hanford C-Farm retrieval mission. A secondary purpose is to identify viable methods/criteria for demonstrating safety relative to DSGREs in the longer term to support the mission to retrieve waste from the Hanford Tank Farms and deliver it to the Waste Treatment and Immobilization Plant (WTP). The potential DSGRE issue resulted in the declaration of a positive Unreviewed Safety Question (USQ). C-Farm retrievals are currently proceeding under a Justification for Continued Operation (JCO) that only allows tanks 241-AN-101 and 241-AN-106 sludge levels of 192 inches and 195 inches, respectively. C-Farm retrievals need deeper sludge levels (approximately 310 inches in 241-AN-101 and approximately 250 inches in 241-AN-106). This effort is to provide analytical data and justification to continue retrievals in a safe and efficient manner.« less

49 CFR 172.331 - Bulk packagings other than portable tanks, cargo tanks, tank cars and multi-unit tank car tanks.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 2 2012-10-01 2012-10-01 false Bulk packagings other than portable tanks, cargo tanks, tank cars and multi-unit tank car tanks. 172.331 Section 172.331 Transportation Other Regulations... packagings other than portable tanks, cargo tanks, tank cars and multi-unit tank car tanks. (a) Each person...

49 CFR 172.331 - Bulk packagings other than portable tanks, cargo tanks, tank cars and multi-unit tank car tanks.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Bulk packagings other than portable tanks, cargo tanks, tank cars and multi-unit tank car tanks. 172.331 Section 172.331 Transportation Other Regulations... packagings other than portable tanks, cargo tanks, tank cars and multi-unit tank car tanks. (a) Each person...

49 CFR 172.331 - Bulk packagings other than portable tanks, cargo tanks, tank cars and multi-unit tank car tanks.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 2 2014-10-01 2014-10-01 false Bulk packagings other than portable tanks, cargo tanks, tank cars and multi-unit tank car tanks. 172.331 Section 172.331 Transportation Other Regulations... packagings other than portable tanks, cargo tanks, tank cars and multi-unit tank car tanks. (a) Each person...

49 CFR 172.331 - Bulk packagings other than portable tanks, cargo tanks, tank cars and multi-unit tank car tanks.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 2 2011-10-01 2011-10-01 false Bulk packagings other than portable tanks, cargo tanks, tank cars and multi-unit tank car tanks. 172.331 Section 172.331 Transportation Other Regulations... packagings other than portable tanks, cargo tanks, tank cars and multi-unit tank car tanks. (a) Each person...

49 CFR 172.331 - Bulk packagings other than portable tanks, cargo tanks, tank cars and multi-unit tank car tanks.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 2 2013-10-01 2013-10-01 false Bulk packagings other than portable tanks, cargo tanks, tank cars and multi-unit tank car tanks. 172.331 Section 172.331 Transportation Other Regulations... packagings other than portable tanks, cargo tanks, tank cars and multi-unit tank car tanks. (a) Each person...

10 CFR 600.241 - Financial reporting.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Financial reporting. 600.241 Section 600.241 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES Uniform Administrative....241 Financial reporting. (a) General. (1) Except as provided in paragraphs (a) (2) and (5) of this...

49 CFR 241.17 - Preemptive effect.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Preemptive effect. 241.17 Section 241.17 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... OPERATIONS § 241.17 Preemptive effect. Under 49 U.S.C. 20106, the regulations in this part preempt any State...

32 CFR 241.11 - Numerical limitation.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 2 2012-07-01 2012-07-01 false Numerical limitation. 241.11 Section 241.11 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED...) § 241.11 Numerical limitation. The ITEP Pilot is an opportunity for the exchange of knowledge...

10 CFR 600.241 - Financial reporting.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Financial reporting. 600.241 Section 600.241 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES Uniform Administrative....241 Financial reporting. (a) General. (1) Except as provided in paragraphs (a) (2) and (5) of this...

Evaluation of the effects of PM101, a cyclodextrin-based formulation of intravenous amiodarone, on blood pressure in healthy humans.

PubMed

Cushing, Daniel J; Adams, Michael P; Cooper, Warren D; Zhang, Bing; Lipicky, Raymond J; Kowey, Peter R

2009-10-15

Intravenous amiodarone (AIV) is used to treat cardiac arrhythmias. Hypotension is the dose-limiting adverse event of AIV and is considered to be due to the cosolvents (polysorbate 80 and benzyl alcohol) in the formulation. To minimize hypotension, the initial loading dose of AIV (150 mg) is diluted to 1.5 mg/ml and slowly infused over 10 minutes. PM101 is a cosolvent-free intravenous formulation of amiodarone. The present study was designed to assess any potential hypotensive effect of PM101 (50 mg/ml) on the administration of the loading dose (150 mg) as an undiluted bolus push. This was a randomized, double-blind, placebo- and active-controlled study in healthy human subjects receiving placebo (5% dextrose in water, n = 112) or PM101 (bolus push, n = 112). The primary end point was the noninferiority assessment of placebo versus PM101 for change in systolic blood pressure. For comparison, the standard loading dose of AIV (150 mg) was infused at 1.5 mg/ml over 10 minutes, and a rapid loading dose of AIV (150 mg) was infused undiluted (50 mg/ml) over 15 seconds. PM101 was noninferior to placebo, with changes from baseline systolic blood pressure for placebo and PM101 of -4.25 +/- 4.2 and -4.83 +/- 5.0 mm Hg, respectively. Neither regimen of AIV altered systolic blood pressure compared to placebo. Transient and significant increases in heart rate were observed in both AIV groups and with PM101 but not placebo. In conclusion, the results of this study demonstrate that PM101 is devoid of hypotension in healthy human subjects. The absence of a hypotensive effect of AIV in this population suggests that further evaluation is needed in a patient population with cardiac disease.

12 CFR 335.241 - Unlisted trading.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Unlisted trading. 335.241 Section 335.241 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY SECURITIES OF NONMEMBER INSURED BANKS § 335.241 Unlisted trading. The provisions of the applicable and...

42 CFR 413.241 - Pharmacy arrangements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 2 2012-10-01 2012-10-01 false Pharmacy arrangements. 413.241 Section 413.241... Disease (ESRD) Services and Organ Procurement Costs § 413.241 Pharmacy arrangements. Effective January 1, 2011, an ESRD facility that enters into an arrangement with a pharmacy to furnish renal dialysis...

42 CFR 413.241 - Pharmacy arrangements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 2 2014-10-01 2014-10-01 false Pharmacy arrangements. 413.241 Section 413.241... Disease (ESRD) Services and Organ Procurement Costs § 413.241 Pharmacy arrangements. Effective January 1, 2011, an ESRD facility that enters into an arrangement with a pharmacy to furnish renal dialysis...

42 CFR 413.241 - Pharmacy arrangements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 2 2013-10-01 2013-10-01 false Pharmacy arrangements. 413.241 Section 413.241... Disease (ESRD) Services and Organ Procurement Costs § 413.241 Pharmacy arrangements. Effective January 1, 2011, an ESRD facility that enters into an arrangement with a pharmacy to furnish renal dialysis...

16 CFR 24.1 - Deception (general).

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Deception (general). 24.1 Section 24.1 Commercial Practices FEDERAL TRADE COMMISSION GUIDES AND TRADE PRACTICE RULES GUIDES FOR SELECT LEATHER AND IMITATION LEATHER PRODUCTS § 24.1 Deception (general). It is unfair or deceptive to misrepresent, directly...

28 CFR 2.41 - Travel approval.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Travel approval. 2.41 Section 2.41..., YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.41 Travel approval. (a) The probation officer may approve travel outside the district without approval of the...

49 CFR 241.19 - Information collection.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Information collection. 241.19 Section 241.19... OPERATIONS § 241.19 Information collection. (a) The information collection requirements of this part are... (44 U.S.C. 3501 et seq.). (b) The information collection requirements are found in the following...

12 CFR 335.241 - Unlisted trading.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 5 2013-01-01 2013-01-01 false Unlisted trading. 335.241 Section 335.241 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY SECURITIES OF NONMEMBER INSURED BANKS § 335.241 Unlisted trading. The provisions of the applicable and...

12 CFR 335.241 - Unlisted trading.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 5 2014-01-01 2014-01-01 false Unlisted trading. 335.241 Section 335.241 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY SECURITIES OF NONMEMBER INSURED BANKS § 335.241 Unlisted trading. The provisions of the applicable and...

12 CFR 335.241 - Unlisted trading.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 5 2012-01-01 2012-01-01 false Unlisted trading. 335.241 Section 335.241 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY SECURITIES OF NONMEMBER INSURED BANKS § 335.241 Unlisted trading. The provisions of the applicable and...

12 CFR 335.241 - Unlisted trading.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Unlisted trading. 335.241 Section 335.241 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY SECURITIES OF NONMEMBER INSURED BANKS § 335.241 Unlisted trading. The provisions of the applicable and...

14 CFR 27.241 - Ground resonance.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Ground resonance. 27.241 Section 27.241... STANDARDS: NORMAL CATEGORY ROTORCRAFT Flight Ground and Water Handling Characteristics § 27.241 Ground resonance. The rotorcraft may have no dangerous tendency to oscillate on the ground with the rotor turning...

14 CFR 29.241 - Ground resonance.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Ground resonance. 29.241 Section 29.241... STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Flight Ground and Water Handling Characteristics § 29.241 Ground resonance. The rotorcraft may have no dangerous tendency to oscillate on the ground with the rotor turning...

14 CFR 27.241 - Ground resonance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Ground resonance. 27.241 Section 27.241... STANDARDS: NORMAL CATEGORY ROTORCRAFT Flight Ground and Water Handling Characteristics § 27.241 Ground resonance. The rotorcraft may have no dangerous tendency to oscillate on the ground with the rotor turning...

14 CFR 29.241 - Ground resonance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Ground resonance. 29.241 Section 29.241... STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Flight Ground and Water Handling Characteristics § 29.241 Ground resonance. The rotorcraft may have no dangerous tendency to oscillate on the ground with the rotor turning...

40 CFR 98.241 - Reporting threshold.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Reporting threshold. 98.241 Section 98.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petrochemical Production § 98.241 Reporting threshold. You must report GHG emissions under this subpart if your...

40 CFR 98.241 - Reporting threshold.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Reporting threshold. 98.241 Section 98.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petrochemical Production § 98.241 Reporting threshold. You must report GHG emissions under this subpart if your...

40 CFR 98.241 - Reporting threshold.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Reporting threshold. 98.241 Section 98.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petrochemical Production § 98.241 Reporting threshold. You must report GHG emissions under this subpart if your...

32 CFR 241.5 - Written agreements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 2 2011-07-01 2011-07-01 false Written agreements. 241.5 Section 241.5 National... PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.5 Written agreements. (a... to be assigned to ITEP must sign a three-party agreement. Prior to the agreement being signed the...

32 CFR 241.5 - Written agreements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 2 2013-07-01 2013-07-01 false Written agreements. 241.5 Section 241.5 National... PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.5 Written agreements. (a... agreement. Prior to the agreement being signed the relevant legal office for the DoD Component shall review...

39 CFR 241.1 - Post offices.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Post offices. 241.1 Section 241.1 Postal Service... DISCONTINUANCE § 241.1 Post offices. (a) Establishment. See § 113.1 of this chapter. (b) Classification. As of July 1 each year, post offices are classified by the Postmaster General based on the allowable postal...

Particle Engulfment and Pushing

NASA Technical Reports Server (NTRS)

2001-01-01

As a liquefied metal solidifies, particles dispersed in the liquid are either pushed ahead of or engulfed by the moving solidification front. Similar effects can be seen when the ground freezes and pushes large particles out of the soil. The Particle Engulfment and Pushing (PEP) experiment, conducted aboard the fourth U.S. Microgravity Payload (USMP-4) mission in 1997, used a glass and plastic beads suspended in a transparent liquid. The liquid was then frozen, trapping or pushing the particles as the solidifying front moved. This simulated the formation of advanced alloys and composite materials. Such studies help scientists to understand how to improve the processes for making advanced materials on Earth. The principal investigator is Dr. Doru Stefanescu of the University of Alabama. This image is from a video downlink.

Tank 40 Final Sludge Batch 8 Chemical Characterization Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bannochie, Christopher J.

2013-09-19

/total organic carbon (TIC/TOC) analyses. Weighted dilutions of slurry were submitted for IC, TIC/TOC, and total base/free OH-/other base analyses. Activities for U-233, U-235, and Pu-239 were determined from the ICP-MS data for the aqua regia digestions of the Tank 40 WAPS slurry using the specific activity of each isotope. The Pu-241 value was determined from a Pu-238/-241 method developed by SRNL AD and previously described.« less

Push Type Fastener

NASA Technical Reports Server (NTRS)

Jackson, Steven A. (Inventor)

1996-01-01

A push type fastener for fastening a movable structural part to a fixed structural part, wherein the coupling and decoupling actions are both a push type operation, the fastener consisting of a plunger having a shank with a plunger head at one end and a threaded end portion at the other end, an expandable grommet adapted to receive the plunger shank there through, and an attachable head which is securable to the threaded end of the plunger shank. The fastener requires each structural part to be provided with an aperture and the attachable head to be smaller than the aperture in the second structural part. The plunger is extensible through the grommet and is structurally configured with an external camming surface which is cooperatively engageable with internal surfaces of the grommet so that when the plunger is inserted in the grommet, the relative positioning of said cooperable camming surfaces determines the expansion of the grommet. Coupling of the parts is effected when the grommet is inserted in the aperture in the fixed structural part and expanded by pushing the plunger head and plunger at least a minimal distance through the grommet. Decoupling is effected by pushing the attachable head.

Project Turnover Deliverables for the SY Farm Enraf Annulus Leak Detectors

DOE Office of Scientific and Technical Information (OSTI.GOV)

SCAIEF, C.C.

2000-09-19

This document identifies the deliverables that ensure the end user of the SY Farm Enraf Annulus Leak Detectors (ALD) has all the documentation and training required for operating and maintaining the new system. All deliverable items checked on the Acceptance For Beneficial Use (ABU) form have been completed and are available to the end user. This document was written as required by HNF-IP-0842, Volume IV section 3.12 Acceptance of Structures, Systems, and Components for Beneficial Use. This document applies to the deliverable documentation required to operate and maintain the SY Farm Enraf ALD System. Appendix A provides a copy ofmore » the ABU form as listed in the appendix of TWR-4092, Engineering Task Plan for the New SY Farm Annulus Leak Detectors. This document attests that all required deliverable items checked on the ABU have been completed and are available to the end user.« less

40 CFR 60.241 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 7 2012-07-01 2012-07-01 false Definitions. 60.241 Section 60.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for the Phosphate Fertilizer Industry...

40 CFR 60.241 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 7 2014-07-01 2014-07-01 false Definitions. 60.241 Section 60.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for the Phosphate Fertilizer Industry...

40 CFR 60.241 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 7 2013-07-01 2013-07-01 false Definitions. 60.241 Section 60.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for the Phosphate Fertilizer Industry...

48 CFR 241.202 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Procedures. 241.202 Section 241.202 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... connection charge. (ii) Termination liability. Use when an obligation is necessary to secure the required...

48 CFR 241.202 - Procedures.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Procedures. 241.202 Section 241.202 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... connection charge. (ii) Termination liability. Use when an obligation is necessary to secure the required...

48 CFR 241.202 - Procedures.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Procedures. 241.202 Section 241.202 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... connection charge. (ii) Termination liability. Use when an obligation is necessary to secure the required...

48 CFR 241.202 - Procedures.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Procedures. 241.202 Section 241.202 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... connection charge. (ii) Termination liability. Use when an obligation is necessary to secure the required...

48 CFR 241.202 - Procedures.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Procedures. 241.202 Section 241.202 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... connection charge. (ii) Termination liability. Use when an obligation is necessary to secure the required...

iSyTE 2.0: a database for expression-based gene discovery in the eye

PubMed Central

Kakrana, Atul; Yang, Andrian; Anand, Deepti; Djordjevic, Djordje; Ramachandruni, Deepti; Singh, Abhyudai; Huang, Hongzhan

2018-01-01

Abstract Although successful in identifying new cataract-linked genes, the previous version of the database iSyTE (integrated Systems Tool for Eye gene discovery) was based on expression information on just three mouse lens stages and was functionally limited to visualization by only UCSC-Genome Browser tracks. To increase its efficacy, here we provide an enhanced iSyTE version 2.0 (URL: http://research.bioinformatics.udel.edu/iSyTE) based on well-curated, comprehensive genome-level lens expression data as a one-stop portal for the effective visualization and analysis of candidate genes in lens development and disease. iSyTE 2.0 includes all publicly available lens Affymetrix and Illumina microarray datasets representing a broad range of embryonic and postnatal stages from wild-type and specific gene-perturbation mouse mutants with eye defects. Further, we developed a new user-friendly web interface for direct access and cogent visualization of the curated expression data, which supports convenient searches and a range of downstream analyses. The utility of these new iSyTE 2.0 features is illustrated through examples of established genes associated with lens development and pathobiology, which serve as tutorials for its application by the end-user. iSyTE 2.0 will facilitate the prioritization of eye development and disease-linked candidate genes in studies involving transcriptomics or next-generation sequencing data, linkage analysis and GWAS approaches. PMID:29036527

Tank 40 Final SB7b Chemical Characterization Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bannochie, C. J.

2012-11-06

, U-235, and Pu-239 were determined from the ICP-MS data for the aqua regia digestions of the Tank 40 WAPS slurry using the specific activity of each isotope. The Pu-241 value was determined from a Pu-238/-241 method.« less

10 CFR 431.241 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Purpose and scope. 431.241 Section 431.241 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT Unit Heaters § 431.241 Purpose and scope. This subpart contains energy conservation requirements...

14 CFR 121.241 - Oil system drains.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Oil system drains. 121.241 Section 121.241..., FLAG, AND SUPPLEMENTAL OPERATIONS Special Airworthiness Requirements § 121.241 Oil system drains... position, must be provided to allow safe drainage of the entire oil system. ...

14 CFR 121.241 - Oil system drains.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Oil system drains. 121.241 Section 121.241..., FLAG, AND SUPPLEMENTAL OPERATIONS Special Airworthiness Requirements § 121.241 Oil system drains... position, must be provided to allow safe drainage of the entire oil system. ...

14 CFR 121.241 - Oil system drains.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Oil system drains. 121.241 Section 121.241..., FLAG, AND SUPPLEMENTAL OPERATIONS Special Airworthiness Requirements § 121.241 Oil system drains... position, must be provided to allow safe drainage of the entire oil system. ...

42 CFR 24.1 - Establishment.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Establishment. 24.1 Section 24.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH... Research Service (SBRS) consisting of members the maximum number of which is prescribed by law. ...

Pushing/bearing down methods for the second stage of labour.

PubMed

Lemos, Andrea; Amorim, Melania Mr; Dornelas de Andrade, Armele; de Souza, Ariani I; Cabral Filho, José Eulálio; Correia, Jailson B

2017-03-26

-effects, I² = 81%) (very low-quality evidence). There was no clear difference in 3rd or 4th degree perineal laceration (risk ratio (RR) 0.87; 95% CI 0.45 to 1.66, one study, 320 women) (low-quality evidence), episiotomy (average RR 1.05; 95% CI 0.60 to 1.85, two studies, 420 women, random-effects, I² = 81%), duration of pushing (MD -9.76 minutes, 95% CI -19.54 to 0.02; two studies; 169 women; I² = 88%) (very low-quality evidence), or rate of spontaneous vaginal delivery (RR 1.01, 95% CI 0.97 to 1.05; five studies; 688 women; I² = 2%) (moderate-quality evidence). For primary neonatal outcomes such as five-minute Apgar score less than seven, there was no clear difference between groups (RR 0.35; 95% CI 0.01 to 8.43, one study, 320 infants) (very low-quality evidence), and the number of admissions to neonatal intensive care (RR 1.08; 95% CI 0.30 to 3.79, two studies, 393 infants) (very low-quality evidence) also showed no clear difference between spontaneous and directed pushing. No data were available on hypoxic ischaemic encephalopathy. Comparison 2: timing of pushing: delayed pushing versus immediate pushing (all women with epidural)For the primary maternal outcomes, delayed pushing was associated with an increase of 56 minutes in the duration of the second stage of labour (MD 56.40, 95% CI 42.05 to 70.76; 11 studies; 3049 women; I² = 91%) (very low-quality evidence), but no clear difference in third or 4th degree perineal laceration (RR 0.94; 95% CI 0.78 to 1.14, seven studies. 2775 women) (moderate-quality evidence) or episiotomy (RR 0.95; 95% CI 0.87 to 1.04, five studies, 2320 women). Delayed pushing was also associated with a 19-minute decrease in the duration of pushing (MD -19.05, 95% CI -32.27 to -5.83; 11 studies; 2932 women; I² = 95%) (very low-quality evidence) and an increase in spontaneous vaginal delivery (RR 1.07; 95% CI 1.02 to 1.11, 12 studies, 3114 women) (moderate-quality evidence).For the primary neonatal outcomes, there was no clear difference

48 CFR 252.241-7001 - Government access.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Government access. 252.241... Clauses 252.241-7001 Government access. As prescribed in 241.501-70(b), use the following clause: Government Access (DEC 1991) Authorized representatives of the Government may have access to the Contractor's...

48 CFR 252.241-7001 - Government access.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Government access. 252.241... Clauses 252.241-7001 Government access. As prescribed in 241.501-70(b), use the following clause: Government Access (DEC 1991) Authorized representatives of the Government may have access to the Contractor's...

48 CFR 252.241-7001 - Government access.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Government access. 252.241... Clauses 252.241-7001 Government access. As prescribed in 241.501-70(b), use the following clause: Government Access (DEC 1991) Authorized representatives of the Government may have access to the Contractor's...

48 CFR 252.241-7001 - Government access.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Government access. 252.241... Clauses 252.241-7001 Government access. As prescribed in 241.501-70(b), use the following clause: Government Access (DEC 1991) Authorized representatives of the Government may have access to the Contractor's...

48 CFR 252.241-7001 - Government access.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Government access. 252.241... Clauses 252.241-7001 Government access. As prescribed in 241.501-70(b), use the following clause: Government Access (DEC 1991) Authorized representatives of the Government may have access to the Contractor's...

Project W-314 acceptance test report HNF-4647 for HNF-4646 241-B pit leak detection ANB-WT-LDSTA-231 for project W-314

DOE Office of Scientific and Technical Information (OSTI.GOV)

HAMMERS, J.S.

The purpose of the test was to verify that the AN Tank Farm B Pit Leak Detector components are functionally integrated and operate in accordance with engineering design specifications. The Acceptance Test Procedure HNF-4646,241-AN-B-Pit Leak Detection ANB-WT-LDSTA-231 was conducted between 26 June and 02 July 1999 at the 200E AN Tank Farm. The test has been completed with no open test exceptions. The test was conducted prior to final engineering ''as built'' activities being completed this had no impact on the procedure or test results. All components, identified in the procedure were found to be labeled and identified as writtenmore » in the procedure.« less

24 CFR 241.875 - Maximum claim period.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Maximum claim period. 241.875 Section 241.875 Housing and Urban Development Regulations Relating to Housing and Urban Development... § 241.875 Maximum claim period. Notice of intention to file claim on a form prescribed by the...

Autophagy regulates chlorpyrifos-induced apoptosis in SH-SY5Y cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, Jae Hyeon; Hanyang Biomedical Research Institute, Seoul; Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul

Recent studies have shown that up-regulation of autophagy may be a tractable therapeutic intervention for clearing disease-causing proteins, including α-synuclein, ubiquitin, and other misfolded or aggregated proteins in pesticide-induced neurodegeneration. In a previous study, we reported that chlorpyrifos (CPF)-induced mitochondria-dependent apoptosis is mediated through reactive oxygen species in SH-SY5Y cells. In this study, we explored a novel pharmacotherapeutic approach to prevent CPF neurotoxicity involving the regulation of autophagy. We investigated the modulation of CPF-induced apoptosis according to autophagy regulation. We found that CPF induced apoptosis in SH-SY5Y cells, as demonstrated by the activation of caspase-3 and nuclear condensation. In addition,more » we observed that cells treated with CPF underwent autophagic cell death by monitoring the expression of LC3-II and p62. Pretreatment with the autophagy inducer rapamycin significantly enhanced the cell viability of CPF-exposed cells, and the enhancement of cell viability was partially due to alleviation of CPF-induced apoptosis via a decrease in levels of cleaved caspase-3. Specifically, rapamycin pretreatment decreased Bax and increased Bcl-2 expression in mitochondria. In addition, rapamycin significantly decreased cytochrome c release in from mitochondria into the cytosol. However, pretreatment of cells with the autophagy inhibitor, 3-methyladenine (3MA), remarkably increased CPF toxicity in these cells; this with correlated with increased expression of Bax and decreased expression of Bcl-2 in mitochondria. Our results suggest that CPF-induced cytotoxicity is modified by autophagy regulation and that rapamycin protects against CPF-induced apoptosis by enhancing autophagy. Pharmacologic induction of autophagy by rapamycin may be a useful treatment strategy in neurodegenerative disorders. - Highlights: ► Chlorpyrifos (CPF) is cytotoxic to SH-SY5Y cells ► CPF-induced cytotoxicity is

40 CFR 241.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... OR INGREDIENTS IN COMBUSTION UNITS General § 241.2 Definitions. For the purposes of this subpart... products of incomplete combustion. Contained means the non-hazardous secondary material is stored in a... with section 241.3(b)(2)(i) from the point of removal from the vehicle through arrival at the...

18 CFR 24.1 - Filing.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Filing. 24.1 Section 24.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF... initial and ultimate installed capacity of the project, the rated horsepower and head on the turbines, and...

18 CFR 24.1 - Filing.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Filing. 24.1 Section 24.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF... initial and ultimate installed capacity of the project, the rated horsepower and head on the turbines, and...

18 CFR 24.1 - Filing.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Filing. 24.1 Section 24.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF... initial and ultimate installed capacity of the project, the rated horsepower and head on the turbines, and...

39 CFR 241.2 - Stations and branches.

Code of Federal Regulations, 2012 CFR

2012-07-01

... number, letter or name. As a general rule, branches are named. (2) Stations and branches transact... 39 Postal Service 1 2012-07-01 2012-07-01 false Stations and branches. 241.2 Section 241.2 Postal... DISCONTINUANCE § 241.2 Stations and branches. (a) Description. (1) Stations are established within the corporate...

39 CFR 241.2 - Stations and branches.

Code of Federal Regulations, 2013 CFR

2013-07-01

... number, letter or name. As a general rule, branches are named. (2) Stations and branches transact... 39 Postal Service 1 2013-07-01 2013-07-01 false Stations and branches. 241.2 Section 241.2 Postal... DISCONTINUANCE § 241.2 Stations and branches. (a) Description. (1) Stations are established within the corporate...

39 CFR 241.2 - Stations and branches.

Code of Federal Regulations, 2014 CFR

2014-07-01

... number, letter or name. As a general rule, branches are named. (2) Stations and branches transact... 39 Postal Service 1 2014-07-01 2014-07-01 false Stations and branches. 241.2 Section 241.2 Postal... DISCONTINUANCE § 241.2 Stations and branches. (a) Description. (1) Stations are established within the corporate...

39 CFR 241.2 - Stations and branches.

Code of Federal Regulations, 2011 CFR

2011-07-01

... number, letter or name. As a general rule, branches are named. (2) Stations and branches transact... 39 Postal Service 1 2011-07-01 2011-07-01 false Stations and branches. 241.2 Section 241.2 Postal... DISCONTINUANCE § 241.2 Stations and branches. (a) Description. (1) Stations are established within the corporate...

39 CFR 241.2 - Stations and branches.

Code of Federal Regulations, 2010 CFR

2010-07-01

... number, letter or name. As a general rule, branches are named. (2) Stations and branches transact... 39 Postal Service 1 2010-07-01 2010-07-01 false Stations and branches. 241.2 Section 241.2 Postal... DISCONTINUANCE § 241.2 Stations and branches. (a) Description. (1) Stations are established within the corporate...

Connected Vehicle Pilot Deployment Program phase 1 : System Requirements Specification (SyRS) : Tampa (THEA) : final report.

DOT National Transportation Integrated Search

2016-08-01

This document describes the System Requirements Specification (SyRS) for the Tampa Hillsborough Expressway Authority (THEA) Connected Vehicle (CV) Pilot Deployment. This SyRS describes the current system requirements derived from the user needs, Conc...

49 CFR 172.330 - Tank cars and multi-unit tank car tanks.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 2 2013-10-01 2013-10-01 false Tank cars and multi-unit tank car tanks. 172.330..., TRAINING REQUIREMENTS, AND SECURITY PLANS Marking § 172.330 Tank cars and multi-unit tank car tanks. (a... material— (1) In a tank car unless the following conditions are met: (i) The tank car must be marked on...

49 CFR 172.330 - Tank cars and multi-unit tank car tanks.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 2 2012-10-01 2012-10-01 false Tank cars and multi-unit tank car tanks. 172.330..., TRAINING REQUIREMENTS, AND SECURITY PLANS Marking § 172.330 Tank cars and multi-unit tank car tanks. (a... material— (1) In a tank car unless the following conditions are met: (i) The tank car must be marked on...

49 CFR 172.330 - Tank cars and multi-unit tank car tanks.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 2 2014-10-01 2014-10-01 false Tank cars and multi-unit tank car tanks. 172.330..., TRAINING REQUIREMENTS, AND SECURITY PLANS Marking § 172.330 Tank cars and multi-unit tank car tanks. (a... material— (1) In a tank car unless the following conditions are met: (i) The tank car must be marked on...

Biosorption of americium-241 by immobilized Rhizopus arrihizus.

PubMed

Liao, Jiali; Yang, Yuanyou; Luo, Shunzhong; Liu, Ning; Jin, Jiannan; Zhang, Taiming; Zhao, Pengji

2004-01-01

Rhizopus arrihizus (R. arrihizus), a fungus, which in previous experiments had shown encouraging ability to remove 241Am from solutions, was immobilized by calcium alginate and other reagents. The various factors affecting 241Am biosorption by the immobilized R. arrihizus were investigated. The results showed that not only can immobilized R. arrihizus adsorb 241Am as efficiently as free R. arrihizus, but that also can be used repeatedly or continuously. The biosorption equilibrium was achieved within 2 h, and more than 94% of 241Am was removed from 241Am solutions of 1.08 MBq/l by immobilized R. arrihizu in the pH range 1-7. Temperature did not affect the adsorption on immobilized R. arrihizus in the range 15-45 degrees C. After repeated adsorption for 8 times, the immobilized R. arrihizus still adsorbed more than 97% of 241Am. At this time, the total adsorption of 241Am was more than 88.6 KBq/g, and had not yet reached saturation. Ninety-five percent of the adsorbed 241Am was desorbed by saturated EDTA solution and 98% by 2 mol/l HNO(3).

Syed Manzoorul Islam's Postmodern Tales: A Study

ERIC Educational Resources Information Center

Sarker, Md Abdul Momen; Talukder, Tusar

2016-01-01

The paper brings into focus how Syed Manzoorul Islam, in his three-decade-long literary career, has mastered a narrative style that sets him apart from many of his Bengali contemporaries. It demonstrates all the traits unique to his storytelling: blurring of boundaries between dream and reality, self-reflexivity, irony, and humor. The research…

32 CFR 241.10 - Small business consideration.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Small business consideration. 241.10 Section 241...) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.10 Small business... each year, at least 20 percent are from small business concerns (as defined by 5 U.S.C. 3703(e)(2)(A...

32 CFR 241.10 - Small business consideration.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 2 2012-07-01 2012-07-01 false Small business consideration. 241.10 Section 241...) § 241.10 Small business consideration. The ASD(NII)/DoD CIO on behalf of the Secretary of Defense shall: (a) Ensure that, of the assignments made each year, at least 20 percent are small business concerns...

32 CFR 241.10 - Small business consideration.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 2 2013-07-01 2013-07-01 false Small business consideration. 241.10 Section 241...) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.10 Small business... each year, at least 20 percent are from small business concerns (as defined by 5 U.S.C. 3703(e)(2)(A...

32 CFR 241.10 - Small business consideration.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 2 2011-07-01 2011-07-01 false Small business consideration. 241.10 Section 241...) MISCELLANEOUS PILOT PROGRAM FOR TEMPORARY EXCHANGE OF INFORMATION TECHNOLOGY PERSONNEL § 241.10 Small business... assignments made each year, at least 20 percent are small business concerns (as defined by 5 U.S.C. 3703(e)(2...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Girardot, Crystal L.; Harlow, Donald G.

This document identifies 241-BY Tank Farm (BY Farm) and 241-TY Tank Farm (TY Farm) leak causes and locations for the 100 series leaking tanks (241-BY-103, 241-TY-103, 241-TY-104, 241-TY-105, and 241-TY-106) identified in RPP-RPT-43704, Hanford BY Farm Leak Assessments Report, and in RPP-RPT-42296, Hanford TY Farm Leak Assessments Report. This document satisfies the BY and TY Farm portion of the target (T04) in Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

27 CFR 25.241 - Production.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Production. 25.241 Section... THE TREASURY LIQUORS BEER Cereal Beverage § 25.241 Production. Brewers may produce cereal beverage and remove it without payment of tax from the brewery. The method of production shall insure that the alcohol...

To push or not to push? Affective influences on moral judgment depend on decision frame.

PubMed

Pastötter, Bernhard; Gleixner, Sabine; Neuhauser, Theresa; Bäuml, Karl-Heinz T

2013-03-01

People's moods can influence moral judgment. Such influences may arise because moods affect moral emotion, or because moods affect moral thought. The present study provides evidence that, at least in the footbridge dilemma, moods affect moral thought. The results of two experiments are reported in which, after induction of positive, negative, or neutral moods and presentation of the footbridge scenario, participants were asked one of two differentially framed closing questions. In the active frame, participants were asked whether they would be active and push the man, making thoughts about pushing accessible; in the passive frame, they were asked whether they would be passive and not push the man, making thoughts about not pushing accessible. The results show that affective influences on moral judgment depended on participants' decision frame. Compared to neutral moods, positive moods induced utilitarian responding - i.e., deciding to push - in the active decision frame, but induced nonutilitarian responding - i.e., deciding to not push - in the passive decision frame; in negative moods, exactly the opposite picture arose. The results suggest that people's moods affect moral judgment by conferring value on moral thought. Positive moods promote and negative moods inhibit accessible thoughts. Copyright © 2012 Elsevier B.V. All rights reserved.

49 CFR 174.63 - Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 2 2014-10-01 2014-10-01 false Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car tanks. 174.63 Section 174.63 Transportation Other....63 Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

49 CFR 174.63 - Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car tanks. 174.63 Section 174.63 Transportation Other....63 Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

49 CFR 174.63 - Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 2 2011-10-01 2011-10-01 false Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car tanks. 174.63 Section 174.63 Transportation Other....63 Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

49 CFR 174.63 - Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 2 2013-10-01 2013-10-01 false Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car tanks. 174.63 Section 174.63 Transportation Other....63 Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

49 CFR 174.63 - Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 2 2012-10-01 2012-10-01 false Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car tanks. 174.63 Section 174.63 Transportation Other....63 Portable tanks, IM portable tanks, IBCs, Large Packagings, cargo tanks, and multi-unit tank car...

Connected Vehicle Pilot Deployment Program Phase 1, System Requirements Specification (SyRS) – New York City.

DOT National Transportation Integrated Search

2016-07-28

This document describes the System Requirements Specification (SyRS) for the New York City Department of Transportation (NYC) Connected Vehicle Pilot Deployment (CVPD) Project. This SyRS describes the results of the definition of need, the operationa...

Paracrine Maturation and Migration of SH-SY5Y Cells by Dental Pulp Stem Cells.

PubMed

Gervois, P; Wolfs, E; Dillen, Y; Hilkens, P; Ratajczak, J; Driesen, R B; Vangansewinkel, T; Bronckaers, A; Brône, B; Struys, T; Lambrichts, I

2017-06-01

Neurological disorders are characterized by neurodegeneration and/or loss of neuronal function, which cannot be adequately repaired by the host. Therefore, there is need for novel treatment options such as cell-based therapies that aim to salvage or reconstitute the lost tissue or that stimulate host repair. The present study aimed to evaluate the paracrine effects of human dental pulp stem cells (hDPSCs) on the migration and neural maturation of human SH-SY5Y neuroblastoma cells. The hDPSC secretome had a significant chemoattractive effect on SH-SY5Y cells as shown by a transwell assay. To evaluate neural maturation, SH-SY5Y cells were first induced toward neuronal cells, after which they were exposed to the hDPSC secretome. In addition, SH-SY5Y cells subjected to the hDPSC secretome showed increased neuritogenesis compared with nonexposed cells. Maturated cells were shown to increase immune reactivity for neuronal markers compared with controls. Ultrastructurally, retinoic acid (RA) signaling and subsequent exposure to the hDPSC secretome induced a gradual rise in metabolic activity and neuronal features such as multivesicular bodies and cytoskeletal elements associated with cellular communication. In addition, electrophysiological recordings of differentiating cells demonstrated a transition toward a neuronal electrophysiological profile based on the maximum tetrodotoxin (TTX)-sensitive, Na + current. Moreover, conditioned medium (CM)-hDPSC-maturated SH-SY5Y cells developed distinct features including, Cd 2+ -sensitive currents, which suggests that CM-hDPSC-maturated SH-SY5Y acquired voltage-gated Ca 2+ channels. The results reported in this study demonstrate the potential of hDPSCs to support differentiation and recruitment of cells with neuronal precursor characteristics in a paracrine manner. Moreover, this in vitro experimental design showed that the widely used SH-SY5Y cell line can improve and simplify the preclinical in vitro research on the molecular

Influence of polluted SY River on child growth and sex hormones.

PubMed

Tang, Chun Yu; Li, An Qi; Guan, Yong Bo; Li, Yan; Cheng, Xue Min; Li, Ping; Li, Shi Qun; Luo, Yi Xin; Huang, Qi; Chen, Hong Yang; Cui, Liu Xin

2012-06-01

To investigate the influence of the polluted SY River on children's growth and sex hormones, and provide scientific data for assessment of the polluted status of the SY River. The study areas were selected randomly from the SY River Basin. Lead (Pb), mercury (Hg), arsenic (As), phthalates (DEP, DBP, DMP, DEHP), and bisphenol A (BPA) were measured both in the river water and in the drinking water. School children were selected by cluster sampling (n=154). Physical development indexes (height, weight, bust-circumference, and skinfold thickness) and sex hormones [testosterone (T) and estradiol (E2)] were measured for all the children. The contents of Pb and Hg exceeded Class V standards of surface water quality in each section of the river and other indicators exceeded Class III. Compared to the control area, the concentrations of Pb, Hg, As, BPA, DEP, and DBP in the drinking water were significantly higher than in the polluted area (P<0.05). Children from the control area had significantly lower E2 and T than children from the polluted area (P<0.05). Among anthropometric results, only skinfold thickness had statistically significant difference between the two groups (P<0.05), while the other indexes showed no significant differences between the two groups (P>0.05). The drinking water has been polluted by the SY River and affected serum sex hormone levels of children living in the polluted area. Copyright © 2012 The Editorial Board of Biomedical and Environmental Sciences. Published by Elsevier B.V. All rights reserved.

Push type fastener

NASA Technical Reports Server (NTRS)

Jackson, Steven A. (Inventor)

1994-01-01

A push type fastener for fastening a movable structural part (41) to a fixed structural part (43), wherein the coupling and decoupling actions are both a push type operation, the fastener consisting of a plunger (12) having a shank (20) with a plunger head (18) at one end and a threaded end portion (26a) at the other end, an expandable grommet (14) adapted to receive the plunger shank (20) therethrough, and an attachable head (16) which is securable to the threaded end of the plunger shank (20). The fastener (10) requires each structural part (41, 43) to be provided with an aperture (45, 46) and the attachable head (16) to be smaller than the aperture (46) in the second structural part. The plunger (12) is extensible through the grommet (14) and is structurally configured with an external camming surface (25) which is cooperatively engageable with internal surfaces (38) of the grommet so that when the plunger is inserted in the grommet, the relative positioning of said cooperable camming surfaces determines the expansion of the grommet. Coupling of the parts is effected when the grommet is inserted in the aperture (46) in the fixed structural part (43) and expanded by pushing the plunger head (18) and plunger at least a minimal distance through the grommet. Decoupling is effected by pushing the attachable head (16).

Scapular kinematics and muscle activities during pushing tasks.

PubMed

Huang, Chun-Kai; Siu, Ka-Chun; Lien, Hen-Yu; Lee, Yun-Ju; Lin, Yang-Hua

2013-01-01

Pushing tasks are functional activities of daily living. However, shoulder complaints exist among workers exposed to regular pushing conditions. It is crucial to investigate the control of shoulder girdles during pushing tasks. The objective of the study was to demonstrate scapular muscle activities and motions on the dominant side during pushing tasks and the relationship between scapular kinematics and muscle activities in different pushing conditions. Thirty healthy adults were recruited to push a four-wheel cart in six pushing conditions. The electromyographic signals of the upper trapezius (UT) and serratus anterior (SA) muscles were recorded. A video-based system was used for measuring the movement of the shoulder girdle and scapular kinematics. Differences in scapular kinematics and muscle activities due to the effects of handle heights and weights of the cart were analyzed using two-way ANOVA with repeated measures. The relationships between scapular kinematics and muscle activities were examined by Pearson's correlation coefficients. The changes in upper trapezius and serratus anterior muscle activities increased significantly with increased pushing weights in the one-step pushing phase. The UT/SA ratio on the dominant side decreases significantly with increased handle heights in the one-step pushing phase. The changes in upward rotation, lateral slide and elevation of the scapula decreased with increased pushing loads in the trunk-forward pushing phase. This study indicated that increased pushing loads result in decreased motions of upward rotation, lateral slide and elevation of the scapula; decreased handle heights result in relatively increased activities of the serratus anterior muscles during pushing tasks.

Hysterosalpingo-foam sonography (HyFoSy): Tolerability, safety and the occurrence of pregnancy post-procedure.

PubMed

Tanaka, Keisuke; Chua, Jackie; Cincotta, Robert; Ballard, Emma L; Duncombe, Gregory

2018-02-01

Fallopian tube patency testing is an essential part of infertility evaluation. Hysterosalpingo-contrast sonography (HyCoSy) has been described as reliable, well tolerated and safe compared to other modalities such as laparoscopy and a dye test or hysterosalpingography. Limited availability of the previously used contrast has led to the introduction of a foam contrast agent as an alternative. To assess the tolerability, safety and occurrence of pregnancy post-procedure of hysterosalpingo-foam sonography (HyFoSy). A retrospective cohort study of women who had a HyFoSy at Queensland Ultrasound for Women from March 2013 to February 2015. A questionnaire was sent to their referring doctor to identify any complications or subsequent pregnancies with or without artificial reproductive technology (ART) within six months of the HyFoSy. Of 200 women, four cases were abandoned due to difficulty introducing the intracervical catheter, severe discomfort or a vasovagal episode. Response from referring doctors for 155 women reported no post-procedural complication. One hundred and eleven women were followed up for at least six months. Twenty-four out of 59 women (40.7%) who had ART and 24 out of 52 women (46.2%) who did not have ART conceived. Fifty percent of women who were nulligravida at the time of investigation, found to have at least one patent fallopian tube, whose partner had a normal semen analysis, spontaneously conceived within the time of follow up. HyFoSy is well tolerated and safe. A preponderance of pregnancies in the first month after HyFoSy suggests that a therapeutic effect may exist. © 2017 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

Concordant 241Pu-241Am Dating of Environmental Samples: Results from Forest Fire Ash

NASA Astrophysics Data System (ADS)

Goldstein, S. J.; Oldham, W. J.; Murrell, M. T.; Katzman, D.

2010-12-01

We have measured the Pu, 237Np, 241Am, and 151Sm isotopic systematics for a set of forest fire ash samples from various locations in the western U.S. including Montana, Wyoming, Idaho, and New Mexico. The goal of this study is to develop a concordant 241Pu (t1/2 = 14.4 y)-241Am dating method for environmental collections. Environmental samples often contain mixtures of components including global fallout. There are a number of approaches for subtracting the global fallout component for such samples. One approach is to use 242Pu/239Pu as a normalizing isotope ratio in a three-isotope plot, where this ratio for the non-global fallout component can be estimated or assumed to be small. This study investigates a new, complementary method of normalization using the long-lived fission product, 151Sm (t1/2 = 90 y). We find that forest fire ash concentrates actinides and fission products with ~1E10 atoms 239Pu/g and ~1E8 atoms 151Sm/g, allowing us to measure these nuclides by mass spectrometric (MIC-TIMS) and radiometric (liquid scintillation counting) methods. The forest fire ash samples are characterized by a western U.S. regional isotopic signature representing varying mixtures of global fallout with a local component from atmospheric testing of nuclear weapons at the Nevada Test Site (NTS). Our results also show that 151Sm is well correlated with the Pu nuclides in the forest fire ash, suggesting that these nuclides have similar geochemical behavior in the environment. Results of this correlation indicate that the 151Sm/239Pu atom ratio for global fallout is ~0.164, in agreement with an independent estimate of 0.165 based on 137Cs fission yields for atmospheric weapons tests at the NTS. 241Pu-241Am dating of the non-global fallout component in the forest fire ash samples yield ages in the late 1950’s-early 1960’s, consistent with a peak in NTS weapons testing at that time. The age results for this component are in agreement using both 242Pu and 151Sm normalizations

LRSAM1 Depletion Affects Neuroblastoma SH-SY5Y Cell Growth and Morphology: The LRSAM1 c.2047-1G>A Loss-of-Function Variant Fails to Rescue The Phenotype.

PubMed

Minaidou, Anna; Nicolaou, Paschalis; Christodoulou, Kyproula

2018-10-01

Deleterious variants in LRSAM1, a RING finger ubiquitin ligase which is also known as TSG101-associated ligase (TAL), have recently been associated with Charcot-Marie-Tooth disease type 2P (CMT2P). The mechanism by which mutant LRSAM1 contributes to the development of neuropathy is currently unclear. The aim of this study was to induce LRSAM1 deficiency in a neuronal cell model, observe its effect on cell growth and morphology and attempt to rescue the phenotype with ancestral and mutant LRSAM1 transfections. In this experimental study, we investigated the effect of LRSAM1 downregulation on neuroblastoma SH-SY5Y cells by siRNA technology where cells were transfected with siRNA against LRSAM1. The effects on the expression levels of TSG101, the only currently known LRSAM1 interacting molecule, were also examined. An equal dosage of ancestral or mutant LRSAM1 construct was transfected in LRSAM1-downregulated cells to investigate its effect on the phenotype of the cells and whether cell proliferation and morphology could be rescued. A significant reduction in TSG101 levels was observed with the downregulation of LRSAM1. In addition, LRSAM1 knockdown significantly decreased the growth rate of SH-SY5Y cells which is caused by a decrease in cell proliferation. An effect on cell morphology was also observed. Furthermore, we overexpressed the ancestral and the c.2047-1G>A mutant LRSAM1 in knocked down cells. Ancestral LRSAM1 recovered cell proliferation and partly the morphology, however, the c.2047-1G>A mutant did not recover cell proliferation and further aggravated the observed changes in cell morphology. Our findings suggest that depletion of LRSAM1 affects neuroblastoma cells growth and morphology and that overexpression of the c.2047-1G>A mutant form, unlike the ancestral LRSAM1, fails to rescue the phenotype. Copyright© by Royan Institute. All rights reserved.

SH-SY5Y human neuroblastoma cell line: in vitro cell model of dopaminergic neurons in Parkinson's disease.

PubMed

Xie, Hong-rong; Hu, Lin-sen; Li, Guo-yi

2010-04-20

To evaluate the human neuroblastoma SH-SY5Y cell line as an in vitro model of dopaminergic (DAergic) neurons for Parkinson's disease (PD) research and to determine the effect of differentiation on this cell model. The data of this review were selected from the original reports and reviews related to SH-SY5Y cells published in Chinese and foreign journals (Pubmed 1973 to 2009). After searching the literature, 60 articles were selected to address this review. The SH-SY5Y cell line has become a popular cell model for PD research because this cell line posses many characteristics of DAergic neurons. For example, these cells express tyrosine hydroxylase and dopamine-beta-hydroxylase, as well as the dopamine transporter. Moreover, this cell line can be differentiated into a functionally mature neuronal phenotype in the presence of various agents. Upon differentiation, SH-SY5Y cells stop proliferating and a constant cell number is subsequently maintained. However, different differentiating agents induce different neuronal phenotypes and biochemical changes. For example, retinoic acid induces differentiation toward a cholinergic neuronal phenotype and increases the susceptibility of SH-SY5Y cells to neurotoxins and neuroprotective agents, whereas treatment with retinoic acid followed by phorbol ester 12-O-tetradecanoylphorbol-13-acetate results in a DAergic neuronal phenotype and decreases the susceptibility of cells to neurotoxins and neuroprotective agents. Some differentiating agents also alter kinetics of 1-methyl-4-phenyl-pyridinium (MPP(+)) uptake, making SH-SY5Y cells more similar to primary mesencephalic neurons. Differentiated and undifferentiated SH-SY5Y cells have been widely used as a cell model of DAergic neurons for PD research. Some differentiating agents afford SH-SY5Y cells with more potential for studying neurotoxicity and neuroprotection and are thus more relevant to experimental PD research.

40 CFR 436.241 - Specialized definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 31 2013-07-01 2013-07-01 false Specialized definitions. 436.241 Section 436.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS (CONTINUED) MINERAL MINING AND PROCESSING POINT SOURCE CATEGORY Diatomite Subcategory...

40 CFR 436.241 - Specialized definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 31 2012-07-01 2012-07-01 false Specialized definitions. 436.241 Section 436.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS (CONTINUED) MINERAL MINING AND PROCESSING POINT SOURCE CATEGORY Diatomite Subcategory...

40 CFR 436.241 - Specialized definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 30 2014-07-01 2014-07-01 false Specialized definitions. 436.241 Section 436.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS (CONTINUED) MINERAL MINING AND PROCESSING POINT SOURCE CATEGORY Diatomite Subcategory...

Foot placement strategy in pushing and pulling.

PubMed

Lee, Tzu-Hsien

2018-01-01

Pushing and pulling tasks are very common in daily and industrial workplaces. They are one major source of musculoskeletal complaints. This study aimed to examine the foot placement strategy while pushing and pulling. Thirteen young males and ten young females were recruited as participants. A two (pushing and pulling) by four (48 cm, 84 cm, 120 cm, and 156 cm) factorial design was used. Exertion direction and exertion height significantly affected foot placement strategy. Pushing task needed more anteroposterior space than pulling task. The percentages of female/male for trailing foot position ranged from 77% to 90% (pushing) and from 80% to 93% (pulling) across the exertion heights. Practitioners should provide an anteroposterior space approximately to 70% body stature for workers to exert their maximum pulling and pushing strengths.

The 1984 eclipse of the symbiotic binary SY Muscae

NASA Technical Reports Server (NTRS)

Kenyon, S. J.; Michalitisianos, A. G.; Lutz, J. H.; Kafatos, M.

1985-01-01

Data from IUE spectra obtained with the 10 x 20-arcsec aperture on May 13, 1984, and optical spectrophotometry obtained with an SIT vidicon on the 1.5-m telescope at CTIO on April 29-May 1, 1984, are reported for the symbiotic binary SY Mus. The data are found to be consistent with a model of a red-giant secondary of 60 solar radii which completely eclipses the hot primary every 627 d but only partially eclipses the 75-solar-radius He(+) region surrounding the primary. The distance to SY Mus is estimated as 1.3 kpc. It is suggested that the large Balmer decrement in eclipse, with (H-alpha)/(H-beta) = 8.3 and (H-beta)/(H-gamma) = 1.5, is associated with an electron density of about 10 to the 10th/cu cm.

33 CFR 136.241 - Compensation allowable.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Compensation allowable. 136.241 Section 136.241 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

33 CFR 136.241 - Compensation allowable.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Compensation allowable. 136.241 Section 136.241 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

33 CFR 136.241 - Compensation allowable.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Compensation allowable. 136.241 Section 136.241 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

33 CFR 136.241 - Compensation allowable.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Compensation allowable. 136.241 Section 136.241 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

33 CFR 136.241 - Compensation allowable.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Compensation allowable. 136.241 Section 136.241 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS...

Fine mapping and identification of candidate genes for the sy-2 locus in a temperature-sensitive chili pepper (Capsicum chinense).

PubMed

Liu, Li; Venkatesh, Jelli; Jo, Yeong Deuk; Koeda, Sota; Hosokawa, Munetaka; Kang, Jin-Ho; Goritschnig, Sandra; Kang, Byoung-Cheorl

2016-08-01

The sy - 2 temperature-sensitive gene from Capsicum chinense was fine mapped to a 138.8-kb region at the distal portion of pepper chromosome 1. Based on expression analyses, two putative F-box genes were identified as sy - 2 candidate genes. Seychelles-2 ('sy-2') is a temperature-sensitive natural mutant of Capsicum chinense, which exhibits an abnormal leaf phenotype when grown at temperatures below 24 °C. We previously showed that the sy-2 phenotype is controlled by a single recessive gene, sy-2, located on pepper chromosome 1. In this study, a high-resolution genetic and physical map for the sy-2 locus was constructed using two individual F2 mapping populations derived from a cross between C. chinense mutant 'sy-2' and wild-type 'No. 3341'. The sy-2 gene was fine mapped to a 138.8-kb region between markers SNP 5-5 and SNP 3-8 at the distal portion of chromosome 1, based on comparative genomic analysis and genomic information from pepper. The sy-2 target region was predicted to contain 27 genes. Expression analysis of these predicted genes showed a differential expression pattern for ORF10 and ORF20 between mutant and wild-type plants; with both having significantly lower expression in 'sy-2' than in wild-type plants. In addition, the coding sequences of both ORF10 and ORF20 contained single nucleotide polymorphisms (SNPs) causing amino acid changes, which may have important functional consequences. ORF10 and ORF20 are predicted to encode F-box proteins, which are components of the SCF complex. Based on the differential expression pattern and the presence of nonsynonymous SNPs, we suggest that these two putative F-box genes are most likely responsible for the temperature-sensitive phenotypes in pepper. Further investigation of these genes may enable a better understanding of the molecular mechanisms of low temperature sensitivity in plants.

System design description for portable 1,000 CFM exhauster Skids POR-007/Skid E and POR-008/Skid F

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nelson, O.D.

1998-07-25

The primary purpose of the two 1,000 CFM Exhauster Skids, POR-007-SKID E and POR-008-SKID F, is to provide backup to the waste tank primary ventilation systems for tanks 241-C-106 and 241-AY-102, and the AY-102 annulus in the event of a failure during the sluicing of tank 241-C-106 and subsequent transfer of sluiced waste to 241-AY-102. This redundancy is required since both of the tank ventilation systems have been declared as Safety Class systems.

24 CFR 241.1050 - Method of loan payment.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Method of loan payment. 241.1050 Section 241.1050 Housing and Urban Development Regulations Relating to Housing and Urban Development...-Eligibility Requirements § 241.1050 Method of loan payment. The loan shall provide for monthly payments on the...

24 CFR 241.1050 - Method of loan payment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Method of loan payment. 241.1050 Section 241.1050 Housing and Urban Development Regulations Relating to Housing and Urban Development...-Eligibility Requirements § 241.1050 Method of loan payment. The loan shall provide for monthly payments on the...

Concordant plutonium-241-americium-241 dating of environmental samples: results from forest fire ash

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldstein, Steven J; Oldham, Warren J; Murrell, Michael T

2010-12-07

We have measured the Pu, {sup 237}Np, {sup 241}Am, and {sup 151}Sm isotopic systematics for a set of forest fire ash samples from various locations in the western U.S. including Montana, Wyoming, Idaho, and New Mexico. The goal of this study is to develop a concordant {sup 241}Pu (t{sub 1/2} = 14.4 y)-{sup 241}Am dating method for environmental collections. Environmental samples often contain mixtures of components including global fallout. There are a number of approaches for subtracting the global fallout component for such samples. One approach is to use {sup 242}/{sup 239}Pu as a normalizing isotope ratio in a three-isotopemore » plot, where this ratio for the nonglobal fallout component can be estimated or assumed to be small. This study investigates a new, complementary method of normalization using the long-lived fission product, {sup 151}Sm (t{sub 1/2} = 90 y). We find that forest fire ash concentrates actinides and fission products with {approx}1E10 atoms {sup 239}Pu/g and {approx}1E8 atoms {sup 151}Sm/g, allowing us to measure these nuclides by mass spectrometric (MIC-TIMS) and radiometric (liquid scintillation counting) methods. The forest fire ash samples are characterized by a western U.S. regional isotopic signature representing varying mixtures of global fallout with a local component from atmospheric testing of nuclear weapons at the Nevada Test Site (NTS). Our results also show that {sup 151}Sm is well correlated with the Pu nuclides in the forest fire ash, suggesting that these nuclides have similar geochemical behavior in the environment. Results of this correlation indicate that the {sup 151}Sm/{sup 239}Pu atom ratio for global fallout is {approx}0.164, in agreement with an independent estimate of 0.165 based on {sup 137}Cs fission yields for atmospheric weapons tests at the NTS. {sup 241}Pu-{sup 241}Am dating of the non-global fallout component in the forest fire ash samples yield ages in the late 1950's-early 1960's, consistent with a peak

24 CFR 241.1245 - Insurance endorsement.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Insurance endorsement. 241.1245... Rights and Obligations § 241.1245 Insurance endorsement. (a) Endorsement. The Commissioner shall indicate his insurance of the equity loan or acquisition loan by endorsing the original credit instrument and...

241Am (n,gamma) isomer ratio measurement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bond, Evelyn M; Vieira, David J; Moody, Walter A

The objective of this project is to improve the accuracy of the {sup 242}Cm/{sup 241}Am radiochemistry ratio. We have performed an activation experiment to measure the {sup 241}Am(n,{gamma}) cross section leading to either the ground state of {sup 242g}Am (t{sub 1/2} = 16 hr) which decays to {sup 242}Cm (t{sub 1/2} = 163 d) or the long-lived isomer {sup 242m}Am (t{sub 1/2} = 141 yr). This experiment will develop a new set of americium cross section evaluations that can be used with a measured {sup 242}Cm/{sup 241}Am radiochemical measurement for nuclear forensic purposes. This measurement is necessary to interpret themore » {sup 242}Cm/{sup 241}Am ratio because a good measurement of this neutron capture isomer ratio for {sup 241}Am does not exist. The targets were prepared in 2007 from {sup 241}Am purified from LANL stocks. Gold was added to the purified {sup 241}Am as an internal neutron fluence monitor. These targets were placed into a holder, packaged, and shipped to Forschungszentrum Karlsruhe, where they were irradiated at their Van de Graff facility in February 2008. One target was irradiated with {approx}25 keV quasimonoenergetic neutrons produced by the {sup 7}Li(p,n) reaction for 3 days and a second target was also irradiated for 3 days with {approx}500 keV neutrons. Because it will be necessary to separate the {sup 242}Cm from the {sup 241}Am in order to measure the amount of {sup 242}Cm by alpha spectrometry, research into methods for americium/curium separations were conducted concurrently. We found that anion exchange chromatography in methanol/nitric acid solutions produced good separations that could be completed in one day resulting in a sample with no residue. The samples were returned from Germany in July 2009 and were counted by gamma spectrometry. Chemical separations have commenced on the blank sample. Each sample will be spiked with {sup 244}Cm, dissolved and digested in nitric acid solutions. One third of each sample will be processed at a

47 CFR 101.1102-101.1105 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false [Reserved] 101.1102-101.1105 Section 101.1102-101.1105 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Competitive Bidding Procedures for LMDS § 101.1102-101.1105 [Reserved] ...

47 CFR 101.1102-101.1105 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 5 2013-10-01 2013-10-01 false [Reserved] 101.1102-101.1105 Section 101.1102-101.1105 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Competitive Bidding Procedures for LMDS §§ 101.1102-101.1105 [Reserved] ...

47 CFR 101.1102-101.1105 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-10-01

... 47 Telecommunication 5 2012-10-01 2012-10-01 false [Reserved] 101.1102-101.1105 Section 101.1102-101.1105 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Competitive Bidding Procedures for LMDS §§ 101.1102-101.1105 [Reserved] ...

47 CFR 101.1102-101.1105 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 5 2011-10-01 2011-10-01 false [Reserved] 101.1102-101.1105 Section 101.1102-101.1105 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Competitive Bidding Procedures for LMDS § 101.1102-101.1105 [Reserved] ...

47 CFR 101.1102-101.1105 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 5 2014-10-01 2014-10-01 false [Reserved] 101.1102-101.1105 Section 101.1102-101.1105 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Competitive Bidding Procedures for LMDS §§ 101.1102-101.1105 [Reserved] ...

24 CFR 241.635 - Regulatory agreement.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Regulatory agreement. 241.635 Section 241.635 Housing and Urban Development Regulations Relating to Housing and Urban Development... Regulatory agreement. Any borrower obligated on the note for any loan insured under this subpart shall be...

24 CFR 241.635 - Regulatory agreement.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Regulatory agreement. 241.635 Section 241.635 Housing and Urban Development Regulations Relating to Housing and Urban Development... Regulatory agreement. Any borrower obligated on the note for any loan insured under this subpart shall be...

24 CFR 241.635 - Regulatory agreement.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Regulatory agreement. 241.635 Section 241.635 Housing and Urban Development Regulations Relating to Housing and Urban Development... Regulatory agreement. Any borrower obligated on the note for any loan insured under this subpart shall be...

24 CFR 241.635 - Regulatory agreement.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Regulatory agreement. 241.635 Section 241.635 Housing and Urban Development Regulations Relating to Housing and Urban Development... Regulatory agreement. Any borrower obligated on the note for any loan insured under this subpart shall be...

41 CFR 101-30.101-8 - Conversion.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 41 Public Contracts and Property Management 2 2011-07-01 2007-07-01 true Conversion. 101-30.101-8 Section 101-30.101-8 Public Contracts and Property Management Federal Property Management Regulations...-General § 101-30.101-8 Conversion. Conversion means the changeover from using existing supply...

41 CFR 101-30.101-8 - Conversion.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Conversion. 101-30.101-8 Section 101-30.101-8 Public Contracts and Property Management Federal Property Management Regulations...-General § 101-30.101-8 Conversion. Conversion means the changeover from using existing supply...

Glutathione transferase-M2-2 secreted from glioblastoma cell protects SH-SY5Y cells from aminochrome neurotoxicity.

PubMed

Cuevas, Carlos; Huenchuguala, Sandro; Muñoz, Patricia; Villa, Monica; Paris, Irmgard; Mannervik, Bengt; Segura-Aguilar, Juan

2015-04-01

U373MG cells are able to take up aminochrome that induces glutathione transferase M2-2 (GSTM2) expression in a concentration-dependent manner where 100 µM aminochrome increases GSTM2 expression by 2.1-fold (P < 0.001) at 3 h. The uptake of (3)H-aminochrome into U373MG cells was significantly reduced in the presence of 2 µM nomifensine (P < 0.001) 100 µM imipramine (P < 0.001) and 50 mM dopamine (P < 0.001). Interestingly, U373MG cells excrete GSTM2 into the conditioned medium and the excretion was significantly increased (2.7-fold; P < 0.001) when the cells were pretreated with 50 µM aminochrome for 3 h. The U373MG-conditioned medium containing GSTM2 protects SH-SY5Y cells incubated with 10 µM aminochrome. The significant protection provided by U373MG-conditioned medium in SH-SY5Y cells incubated with aminochrome was dependent on GSTM2 internalization into SH-SY5Y cells as evidenced by (i) uptake of (14)C-GSTM2 released from U373MG cells into SH-SY5Y cells, a process inhibited by anti-GSTM2 antiserum; (ii) lack of protection of U373MG-conditioned medium in the presence of anti-GSTM2 antiserum on SH-SY5Y cells treated with aminochrome; and (iii) lack of protection of conditioned medium from U373MGsiGST6 that expresses an siRNA directed against GSTM2 on SH-SY5Y cells treated with aminochrome. In conclusion, our results demonstrated that U373MG cells protect SH-SY5Y cells against aminochrome neurotoxicity by releasing GSTM2 into the conditioned medium and subsequent internalization of GSTM2 into SH-SY5Y cells. These results suggest a new mechanism of protection of dopaminergic neurons mediated by astrocytes by releasing GSTM2 into the intersynaptic space and subsequent internalization into dopaminergic neuron in order to protect these cells against aminochrome neurotoxicity.

Push-Pull Locomotion for Vehicle Extrication

NASA Technical Reports Server (NTRS)

Creager, Colin M.; Johnson, Kyle A.; Plant, Mark; Moreland, Scott J.; Skonieczny, Krzysztof

2014-01-01

For applications in which unmanned vehicles must traverse unfamiliar terrain, there often exists the risk of vehicle entrapment. Typically, this risk can be reduced by using feedback from on-board sensors that assess the terrain. This work addressed the situations where a vehicle has already become immobilized or the desired route cannot be traversed using conventional rolling. Specifically, the focus was on using push-pull locomotion in high sinkage granular material. Push-pull locomotion is an alternative mode of travel that generates thrust through articulated motion, using vehicle components as anchors to push or pull against. It has been revealed through previous research that push-pull locomotion has the capacity for generating higher net traction forces than rolling, and a unique optical flow technique indicated that this is the result of a more efficient soil shearing method. It has now been found that pushpull locomotion results in less sinkage, lower travel reduction, and better power efficiency in high sinkage material as compared to rolling. Even when starting from an "entrapped" condition, push-pull locomotion was able to extricate the test vehicle. It is the authors' recommendation that push-pull locomotion be considered as a reliable back-up mode of travel for applications where terrain entrapment is a possibility.

Hydrogen peroxide toxicity induces Ras signaling in human neuroblastoma SH-SY5Y cultured cells.

PubMed

Chetsawang, Jirapa; Govitrapong, Piyarat; Chetsawang, Banthit

2010-01-01

It has been reported that overproduction of reactive oxygen species occurs after brain injury and mediates neuronal cells degeneration. In the present study, we examined the role of Ras signaling on hydrogen peroxide-induced neuronal cells degeneration in dopaminergic neuroblastoma SH-SY5Y cells. Hydrogen peroxide significantly reduced cell viability in SH-SY5Y cultured cells. An inhibitor of the enzyme that catalyzes the farnesylation of Ras proteins, FTI-277, and a competitive inhibitor of GTP-binding proteins, GDP-beta-S significantly decreased hydrogen peroxide-induced reduction in cell viability in SH-SY5Y cultured cells. The results of this study might indicate that a Ras-dependent signaling pathway plays a role in hydrogen peroxide-induced toxicity in neuronal cells.

24 CFR 241.251 - Cross-reference.

Code of Federal Regulations, 2010 CFR

2010-04-01

... SUPPLEMENTARY FINANCING FOR INSURED PROJECT MORTGAGES Contract Rights and Obligations § 241.251 Cross-reference. (a) Projects with a HUD-insured or HUD-held mortgage. All of the provisions of subpart B, part 207 of... force and effect to multifamily project and group practice facility mortgages insured under section 241...

24 CFR 241.885 - Insurance benefits.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Insurance benefits. 241.885 Section... § 241.885 Insurance benefits. (a) Method of payment. Payment of claims shall be made in the following... acceptable assignment of the note and security instrument to the Commissioner, the insurance benefits shall...

24 CFR 241.885 - Insurance benefits.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Insurance benefits. 241.885 Section... § 241.885 Insurance benefits. (a) Method of payment. Payment of claims shall be made in the following... acceptable assignment of the note and security instrument to the Commissioner, the insurance benefits shall...

24 CFR 241.885 - Insurance benefits.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Insurance benefits. 241.885 Section... § 241.885 Insurance benefits. (a) Method of payment. Payment of claims shall be made in the following... acceptable assignment of the note and security instrument to the Commissioner, the insurance benefits shall...

24 CFR 241.885 - Insurance benefits.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Insurance benefits. 241.885 Section... § 241.885 Insurance benefits. (a) Method of payment. Payment of claims shall be made in the following... acceptable assignment of the note and security instrument to the Commissioner, the insurance benefits shall...

24 CFR 241.885 - Insurance benefits.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Insurance benefits. 241.885 Section... § 241.885 Insurance benefits. (a) Method of payment. Payment of claims shall be made in the following... acceptable assignment of the note and security instrument to the Commissioner, the insurance benefits shall...

75 FR 74608 - Airworthiness Directives; CENTRAIR Models 101, 101A, 101P, and 101AP Gliders

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-01

... Airworthiness Directives; CENTRAIR Models 101, 101A, 101P, and 101AP Gliders AGENCY: Federal Aviation...[eacute] Nouvelle (SN) Centrair. This tube had been reinforced in 1984 with a modification. Gliders...[eacute] Nouvelle (SN) Centrair. This tube had been reinforced in 1984 with a modification. Gliders...

Report on data requirements and hardware selection for in-situ ball viscometer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shepard, C.L.

1994-12-01

The in-situ ball rheometer is designed to provide data concerning the rheological properties of the waste contained in tank 101-SY. It is imperative that the data collected and the results obtained are useful to the community presently concerned with the mitigation of the waste contained within this tank. To ensure that this objective is met, discussions were held with representatives of different groups in order to determine their data needs. This report is a synopsis of these discussions. Four separate groups were identified as potential users of the data. Persons contacted included Don Trent (Pacific Northwest Laboratory (PNL)), who ismore » involved with Tempest modeling of the tank; Randy Marlow and John Strehlow (Westinghouse Hanford Company (WHC)), involved with structural analysis of the tank; Kemal Pasamehmetoglu and Cetin Unal (Los Alamos National Laboratory (LANL)), who are concerned with the safety analysis of activities performed within the tank; and Judith Bamberger, Paul Scott, and Gita Golcar (PNL) who are involved with the eventual retrieval of waste from the tank. Very specific questions were asked of these groups, including: From where in the tank are data needed? When should data be collected? In what manner are the data useful? What is the required accuracy of the data? Responses from each group are given.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Girardot, Crystal L.; Harlow, Donald G.

This document identifies 241-SX Tank Farm (SX Farm) leak causes and locations for the 100 series leaking tanks (241-SX-107, 241-SX-108, 241-SX-109, 241-SX-111, 241-SX-112, 241-SX-113, 241-SX-114, and 241-SX-115) identified in RPP-ENV-39658, Rev. 0, Hanford SX-Farm Leak Assessments Report. This document satisfies the SX Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

In situ Spectroscopic Analysis and Quantification of [Tc(CO)3]+ in Hanford Tank Waste.

PubMed

Branch, Shirmir D; French, Amanda D; Lines, Amanda M; Soderquist, Chuck Z; Rapko, Brian M; Heineman, William R; Bryan, Samuel A

2018-06-12

The quantitative conversion of non-pertechnetate [Tc(CO)3]+ species in nuclear waste storage tank 241-AN-102 at the Hanford Site is demonstrated. A waste sample containing the [Tc(CO)3]+ species is added to a developer solution that rapidly converts the non-emissive species into a luminescent complex, which is detected spectroscopically. This method was first demonstrated using a [Tc(CO)3]+ sample non-waste containing matrix to determine a detection limit (LOD), resulting in a [Tc(CO)3]+ LOD of 2.20 × 10-7 M, very near the LOD of the independently synthesized standard (2.10 × 10-7 M). The method was then used to detect [Tc(CO)3]+ in a simulated waste using the standard addition method, resulting in a [Tc(CO)3]+ concentration of 1.89 × 10-5 M (within 27.7% of the concentration determined by β- liquid scintillation counting). Three samples from 241-AN-102 were tested by the standard addition method: (1) a 5 M Na adjusted fraction, (2) a fraction depleted of 137Cs, (3) and an acid-stripped eluate. The concentrations of [Tc(CO)3]+ in these fractions were determined to be 9.90 × 10-6 M (1), 0 M (2), and 2.46 × 10-6 M (3), respectively. The concentration of [Tc(CO)3]+ in the as-received AN-102 tank waste supernatant was determined to be 1.84 × 10-5 M.

TANK 40 FINAL SB7B CHEMICAL CHARACTERIZATION RESULTS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bannochie, C.

2012-03-15

), total base/free OH{sup -}/other base, total inorganic carbon/total organic carbon (TIC/TOC) analyses, and Cs-137 gamma scan. Weighted dilutions of slurry were submitted for IC, TIC/TOC, and total base/free OH{sup -}/other base analyses. Activities for U-233, U-235, and Pu-239 were determined from the ICP-MS data for the aqua regia digestions of the Tank 40 WAPS slurry using the specific activity of each isotope. The Pu-241 value was determined from a Pu-238/-241 method developed by SRNL AD and previously described. The following conclusions were drawn from the analytical results reported here: (1) The ratios of the major elements for the SB7b WAPS sample are different from those measured for the SB7a WAPS sample. There is less Al and Mn relative to Fe than the previous sludge batch. (2) The elemental composition of this sample and the analyses conducted here are reasonable and consistent with DWPF batch data measurements in light of DWPF pre-sample concentration and SRAT product heel contributions to the DWPF SRAT receipt analyses. The element ratios for Al/Fe, Ca/Fe, Mn/Fe, and U/Fe agree within 10% between this work and the DWPF Sludge Receipt and Adjustment Tank (SRAT) receipt analyses. (3) Sulfur in the SB7b WAPS sample is 82% soluble, slightly less than results reported for SB3, SB4, and SB6 samples but unlike the 50% insoluble sulfur observed in the SB5 WAPS sample. In addition, 23% of the soluble sulfur is not present as sulfate in SB7b. (4) The average activities of the fissile isotopes of interest in the SB7b WAPS sample are (in {mu}Ci/g of total dried solids): 4.22E-02 U-233, 6.12E-04 U-235, 1.08E+01 Pu-239, and 5.09E+01 Pu-241. The full radionuclide composition will be reported in a future document. (5) The fission product noble metal and Ag concentrations appear to have largely peaked in previous DWPF sludge batches, with the exception of Ru, which still shows a slight increase in SB7b.« less

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-101

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.

2000-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle Mission STS-101. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-101 and the resulting effect on the Space Shuttle Program.

24 CFR 241.805 - Insurance premiums.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Insurance premiums. 241.805 Section... Without a HUD-Insured or HUD-Held Mortgage Premiums § 241.805 Insurance premiums. (a) First premium. The... insurance premium equal to one percent of the original face amount of the note. (b) Second premium. The...

24 CFR 241.805 - Insurance premiums.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Insurance premiums. 241.805 Section... Without a HUD-Insured or HUD-Held Mortgage Premiums § 241.805 Insurance premiums. (a) First premium. The... insurance premium equal to one percent of the original face amount of the note. (b) Second premium. The...

Citizen Contributions to the Closure of High-Level Waste (HLW) Tanks 18 and 19 at the Department of Energy's (DOE) Savannah River Site (SRS) - 13448

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lawless, W.F.

2013-07-01

Citizen involvement in DOE's decision-making for the environmental cleanup from DOE's management of its nuclear wastes across the DOE complex has had a positive effect on the cleanup of its SRS site, characterized by an acceleration of cleanup not only for the Transuranic wastes at SRS, but also for DOE's first two closures of HLW tanks, both of which occurred at SRS. The Citizens around SRS had pushed successfully for the closures of Tanks 17 and 20 in 1997, becoming the first closures of HLW tanks under regulatory guidance in the USA. However, since then, HLW tank closures ceased duemore » to a lawsuit, the application of new tank clean-up technology, interagency squabbling between DOE and NRC over tank closure criteria, and finally and almost fatally, from budget pressures. Despite an agreement with its regulators for the closure of Tanks 18 and 19 by the end of calendar year 2012, the outlook in Fall 2011 to close these two tanks had dimmed. It was at this point that the citizens around SRS became reengaged with tank closures, helping DOE to reach its agreed upon milestone. (authors)« less

SenSyF Experience on Integration of EO Services in a Generic, Cloud-Based EO Exploitation Platform

NASA Astrophysics Data System (ADS)

Almeida, Nuno; Catarino, Nuno; Gutierrez, Antonio; Grosso, Nuno; Andrade, Joao; Caumont, Herve; Goncalves, Pedro; Villa, Guillermo; Mangin, Antoine; Serra, Romain; Johnsen, Harald; Grydeland, Tom; Emsley, Stephen; Jauch, Eduardo; Moreno, Jose; Ruiz, Antonio

2016-08-01

SenSyF is a cloud-based data processing framework for EO- based services. It has been pioneer in addressing Big Data issues from the Earth Observation point of view, and is a precursor of several of the technologies and methodologies that will be deployed in ESA's Thematic Exploitation Platforms and other related systems.The SenSyF system focuses on developing fully automated data management, together with access to a processing and exploitation framework, including Earth Observation specific tools. SenSyF is both a development and validation platform for data intensive applications using Earth Observation data. With SenSyF, scientific, institutional or commercial institutions developing EO- based applications and services can take advantage of distributed computational and storage resources, tailored for applications dependent on big Earth Observation data, and without resorting to deep infrastructure and technological investments.This paper describes the integration process and the experience gathered from different EO Service providers during the project.

Push-pull farming systems.

PubMed

Pickett, John A; Woodcock, Christine M; Midega, Charles A O; Khan, Zeyaur R

2014-04-01

Farming systems for pest control, based on the stimulo-deterrent diversionary strategy or push-pull system, have become an important target for sustainable intensification of food production. A prominent example is push-pull developed in sub-Saharan Africa using a combination of companion plants delivering semiochemicals, as plant secondary metabolites, for smallholder farming cereal production, initially against lepidopterous stem borers. Opportunities are being developed for other regions and farming ecosystems. New semiochemical tools and delivery systems, including GM, are being incorporated to exploit further opportunities for mainstream arable farming systems. By delivering the push and pull effects as secondary metabolites, for example, (E)-4,8-dimethyl-1,3,7-nonatriene repelling pests and attracting beneficial insects, problems of high volatility and instability are overcome and compounds are produced when and where required. Copyright © 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.

Characterization of Differentiated SH-SY5Y as Neuronal Screening Model Reveals Increased Oxidative Vulnerability

PubMed Central

Forster, J. I.; Köglsberger, S.; Trefois, C.; Boyd, O.; Baumuratov, A. S.; Buck, L.; Balling, R.; Antony, P. M. A.

2016-01-01

The immortalized and proliferative cell line SH-SY5Y is one of the most commonly used cell lines in neuroscience and neuroblastoma research. However, undifferentiated SH-SY5Y cells share few properties with mature neurons. In this study, we present an optimized neuronal differentiation protocol for SH-SY5Y that requires only two work steps and 6 days. After differentiation, the cells present increased levels of ATP and plasma membrane activity but reduced expression of energetic stress response genes. Differentiation results in reduced mitochondrial membrane potential and decreased robustness toward perturbations with 6-hydroxydopamine. We are convinced that the presented differentiation method will leverage genetic and chemical high-throughput screening projects targeting pathways that are involved in the selective vulnerability of neurons with high energetic stress levels. PMID:26738520

49 CFR 179.100-1 - Tanks built under these specifications shall comply with the requirements of §§ 179.100, 179.101...

Code of Federal Regulations, 2013 CFR

2013-10-01

...) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120...

49 CFR 179.100-1 - Tanks built under these specifications shall comply with the requirements of §§ 179.100, 179.101...

Code of Federal Regulations, 2014 CFR

2014-10-01

...) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120...

49 CFR 179.100-1 - Tanks built under these specifications shall comply with the requirements of §§ 179.100, 179.101...

Code of Federal Regulations, 2010 CFR

2010-10-01

... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120...

49 CFR 179.100-1 - Tanks built under these specifications shall comply with the requirements of §§ 179.100, 179.101...

Code of Federal Regulations, 2011 CFR

2011-10-01

...) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120...

'Mister Badger' Pushing Mars Rock

NASA Technical Reports Server (NTRS)

1976-01-01

Viking's soil sampler collector arm successfully pushed a rock on the surface of Mars during the afternoon of Friday, October 8. The irregular-shaped rock was pushed several inches by the Lander's collector arm, which displaced the rock to the left of its original position, leaving it cocked slightly upward. Photographs and other information verified the successful rock push. Photo at left shows the soil sampler's collector head pushing against the rock, named 'Mister Badger' by flight controllers. Photo at right shows the displaced rock and the depression whence it came. Part of the soil displacement was caused by the collector s backhoe. A soil sample will be taken from the site Monday night, October 11. It will then be delivered to Viking s organic chemistry instrument for a series of analyses during the next few weeks. The sample is being sought from beneath a rock because scientists believe that, if there are life forms on Mars, they may seek rocks as shelter from the Sun s intense ultraviolet radiation.

Kinematic Analysis of Four Plyometric Push-Up Variations

PubMed Central

MOORE, LAURA H.; TANKOVICH, MICHAEL J.; RIEMANN, BRYAN L.; DAVIES, GEORGE J.

2012-01-01

Plyometric research in the upper extremity is limited, with the effects of open-chain plyometric exercises being studied most. Kinematic and ground reaction force data concerning closed-chain upper extremity plyometrics has yet to be examined. Twenty-one recreationally active male subjects performed four variations of plyometric push-ups in a counterbalanced order. These included box drop push-ups from 3.8 cm, 7.6 cm, 11.4 cm heights, and clap push-ups. Kinematics of the trunk, dominant extremity and both hands were collected to examine peak flight, elbow flexion at ground contact, elbow displacement, and hand separation. Additionally peak vertical ground reaction force was measured under the dominant extremity. The 11.4 cm and clap push-ups had significantly higher peak flight than the other variations (P<.001). At ground contact, the elbow was in significantly greater flexion for the 3.8 cm and clap push-up compared to the other variations (P<.001). The clap push-up had significantly more elbow displacement than the other variations (P<.001) while hand separation was not significantly different between variations (P=.129). Peak vertical ground reaction force was significantly greater for the clap push-ups than for all other variations (P< .001). Despite similar flight heights between the 11.4 cm and clap push-ups, the greater peak vertical ground reaction force and elbow displacement of the clap push-ups indicates the clap push-up is the most intense of the variations examined. Understanding the kinematic variables involved will aid in the creation of a closed chain upper-extremity plyometric progression. PMID:27182390

9 CFR 354.241 - Cleaning of rooms and compartments.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Cleaning of rooms and compartments. 354.241 Section 354.241 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF... Sanitary Conditions and Precautions Against Contamination of Products § 354.241 Cleaning of rooms and...

25 CFR 241.5 - Commercial fishing, Karluk Indian Reservation.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false Commercial fishing, Karluk Indian Reservation. 241.5 Section 241.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE INDIAN FISHING IN ALASKA § 241.5 Commercial fishing, Karluk Indian Reservation. (a) Definition. The Karluk Indian...

25 CFR 241.5 - Commercial fishing, Karluk Indian Reservation.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 1 2012-04-01 2011-04-01 true Commercial fishing, Karluk Indian Reservation. 241.5 Section 241.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE INDIAN FISHING IN ALASKA § 241.5 Commercial fishing, Karluk Indian Reservation. (a) Definition. The Karluk Indian...

25 CFR 241.5 - Commercial fishing, Karluk Indian Reservation.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Commercial fishing, Karluk Indian Reservation. 241.5 Section 241.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE INDIAN FISHING IN ALASKA § 241.5 Commercial fishing, Karluk Indian Reservation. (a) Definition. The Karluk Indian...

25 CFR 241.5 - Commercial fishing, Karluk Indian Reservation.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 1 2013-04-01 2013-04-01 false Commercial fishing, Karluk Indian Reservation. 241.5 Section 241.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE INDIAN FISHING IN ALASKA § 241.5 Commercial fishing, Karluk Indian Reservation. (a) Definition. The Karluk Indian...

Characterization of DWPF recycle condensate tank materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bannochie, C. J.

2015-01-01

A Defense Waste Processing Facility (DWPF) Recycle Condensate Tank (RCT) sample was delivered to the Savannah River National Laboratory (SRNL) for characterization with particular interest in the concentration of I-129, U-233, U-235, total U, and total Pu. Since a portion of Salt Batch 8 will contain DWPF recycle materials, the concentration of I-129 is important to undertand for salt batch planning purposes. The chemical and physical characterizations are also needed as input to the interpretation of future work aimed at determining the propensity of the RCT material to foam, and methods to remediate any foaming potential. According to DWPF themore » Tank Farm 2H evaporator has experienced foaming while processing DWPF recycle materials. The characterization work on the RCT samples has been completed and is reported here. The composition of the Sludge Batch 8 (SB8) RCT material is largely a low base solution of 0.2M NaNO 2 and 0.1M NaNO 3 with a small amount of formate present. Insoluble solids comprise only 0.05 wt.% of the slurry. The solids appear to be largely sludge-like solids based on elemental composition and SEM-EDS analysis. The sample contains an elevated concentration of I-129 (38x) and substantial 59% fraction of Tc-99, as compared to the incoming SB8 Tank 40 feed material. The Hg concentration is 5x, when compared to Fe, of that expected based on sludge carryover. The total U and Pu concentrations are reduced significantly, 0.536 wt.% TS and 2.42E-03 wt.% TS, respectively, with the fissile components, U-233, U-235, Pu-239, and Pu-241, an order of magnitude lower in concentration than those in the SB8 Tank 40 DWPF feed material. This report will be revised to include the foaming study requested in the TTR and outlined in the TTQAP when that work is concluded.« less

Hydraulic tests with direct-push equipment

USGS Publications Warehouse

Butler, J.J.; Healey, J.M.; McCall, G.W.; Garnett, E.J.; Loheide, Steven P.

2002-01-01

The potential of direct-push technology for hydraulic characterization of saturated flow systems was investigated at a field site with a considerable degree of subsurface control. Direct-push installations were emplaced by attaching short lengths of screen (shielded and unshielded) to the bottom end of a tool string that was then advanced into the unconsolidated sediments. A series of constant-rate pumping tests were performed in a coarse sand and gravel aquifer using direct-push tool strings as observation wells. Very good agreement (within 4%) was found between hydraulic conductivity (K) estimates from direct-push installations and those from conventional wells. A program of slug tests was performed in direct-push installations using small-diameter adaptations of solid-slug and pneumatic methods. In a sandy silt interval of moderate hydraulic conductivity, K values from tests in a shielded screen tool were in excellent agreement (within 2%) with those from tests in a nearby well. In the coarse sand and gravel aquifer, K values were within 12% of those from multilevel slug tests at a nearby well. However, in the more permeable portions of the aquifer (K > 70 m/day), the smaller-diameter direct-push rods (0.016 m inner diameter [I.D.]) attenuated test responses, leading to an underprediction of K. In those conditions, use of larger-diameter rods (e.g., 0.038 m I.D.) is necessary to obtain K values representative of the formation. This investigation demonstrates that much valuable information can be obtained from hydraulic tests in direct-push installations. As with any type of hydraulic test, K estimates are critically dependent on use of appropriate emplacement and development procedures. In particular, driving an unshielded screen through a heterogeneous sequence will often lead to a buildup of low-K material that can be difficult to remove with standard development procedures.

syNErgy: A Case Study in Workforce Curriculum Development

ERIC Educational Resources Information Center

Killingsworth, John; Grosskopf, Kevin R.

2013-01-01

With high unemployment and structural changes to industry, workforce development in the United States is a growing concern. Many semiskilled workers lack knowledge, skills, and abilities to be competitive for reemployment to green jobs. Nebraska's syNErgy research grant was introduced to address the training needs of unemployed and underemployed…

41 CFR 101-30.101-11 - Recorded data.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 41 Public Contracts and Property Management 2 2013-07-01 2012-07-01 true Recorded data. 101-30.101-11 Section 101-30.101-11 Public Contracts and Property Management Federal Property Management....1-General § 101-30.101-11 Recorded data. Recorded data means the data which are associated with a...

41 CFR 101-30.101-11 - Recorded data.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 41 Public Contracts and Property Management 2 2014-07-01 2012-07-01 true Recorded data. 101-30.101-11 Section 101-30.101-11 Public Contracts and Property Management Federal Property Management....1-General § 101-30.101-11 Recorded data. Recorded data means the data which are associated with a...

41 CFR 101-30.101-11 - Recorded data.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 41 Public Contracts and Property Management 2 2012-07-01 2012-07-01 false Recorded data. 101-30.101-11 Section 101-30.101-11 Public Contracts and Property Management Federal Property Management....1-General § 101-30.101-11 Recorded data. Recorded data means the data which are associated with a...

41 CFR 101-30.101-11 - Recorded data.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 41 Public Contracts and Property Management 2 2011-07-01 2007-07-01 true Recorded data. 101-30.101-11 Section 101-30.101-11 Public Contracts and Property Management Federal Property Management....1-General § 101-30.101-11 Recorded data. Recorded data means the data which are associated with a...

41 CFR 101-30.101-11 - Recorded data.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Recorded data. 101-30.101-11 Section 101-30.101-11 Public Contracts and Property Management Federal Property Management....1-General § 101-30.101-11 Recorded data. Recorded data means the data which are associated with a...

25 CFR 241.3 - Commercial fishing, Annette Islands Reserve.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 1 2012-04-01 2011-04-01 true Commercial fishing, Annette Islands Reserve. 241.3 Section 241.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE INDIAN FISHING IN ALASKA § 241.3 Commercial fishing, Annette Islands Reserve. (a) Definition. Commercial fishing is the...

Low-Back Biomechanics and Static Stability During Isometric Pushing

PubMed Central

Granata, Kevin P.; Bennett, Bradford C.

2006-01-01

Pushing and pulling tasks are increasingly prevalent in industrial workplaces. Few studies have investigated low-back biomechanical risk factors associated with pushing, and we are aware of none that has quantified spinal stability during pushing exertions. Data recorded from 11 healthy participants performing isometric pushing exertions demonstrated that trunk posture, vector force direction of the applied load, and trunk moment were influenced (p < .01) by exertion level, elevation of the handle for the pushing task, and foot position. A biomechanical model was used to analyze the posture and hand force data gathered from the pushing exertions. Model results indicate that pushing exertions provide significantly (p < .01) less stability than lifting when antagonistic cocontraction is ignored. However, stability can be augmented by recruitment of muscle cocontraction. Results suggest that cocontraction may be recruited to compensate for the fact that equilibrium mechanics provide little intrinsic trunk stiffness and stability during pushing exertions. If one maintains stability by means of cocontraction, additional spinal load is thereby created, increasing the risk of overload injury. Thus it is important to consider muscle cocontraction when evaluating the biomechanics of pushing exertions. Potential applications of this research include improved assessment of biomechanical risk factors for the design of industrial pushing tasks. PMID:16435695

24 CFR 241.1070 - Agreed interest rate.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Agreed interest rate. 241.1070...-Eligibility Requirements § 241.1070 Agreed interest rate. The equity or acquisition loan shall bear interest at the rate agreed upon by the borrower and the lender. ...

14 CFR 121.241 - Oil system drains.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Oil system drains. 121.241 Section 121.241 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS... position, must be provided to allow safe drainage of the entire oil system. ...

14 CFR 121.241 - Oil system drains.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Oil system drains. 121.241 Section 121.241 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS... position, must be provided to allow safe drainage of the entire oil system. ...

241Am Ingrowth and Its Effect on Internal Dose

DOE PAGES

Konzen, Kevin

2016-07-01

Generally, plutonium has been manufactured to support commercial and military applications involving heat sources, weapons and reactor fuel. This work focuses on three typical plutonium mixtures, while observing the potential of 241Am ingrowth and its effect on internal dose. The term “ingrowth” is used to describe 241Am production due solely from the decay of 241Pu as part of a plutonium mixture, where it is initially absent or present in a smaller quantity. Dose calculation models do not account for 241Am ingrowth unless the 241Pu quantity is specified. This work suggested that 241Am ingrowth be considered in bioassay analysis when theremore » is a potential of a 10% increase to the individual’s committed effective dose. It was determined that plutonium fuel mixtures, initially absent of 241Am, would likely exceed 10% for typical reactor grade fuel aged less than 30 years; however, heat source grade and aged weapons grade fuel would normally fall below this threshold. In conclusion, although this work addresses typical plutonium mixtures following separation, it may be extended to irradiated commercial uranium fuel and is expected to be a concern in the recycling of spent fuel.« less

Delayed versus immediate pushing in second stage of labor.

PubMed

Kelly, Mary; Johnson, Eileen; Lee, Vickie; Massey, Liz; Purser, Debbie; Ring, Karen; Sanderson, Stephanye; Styles, Juanita; Wood, Deb

2010-01-01

Comparison of two different methods for management of second stage of labor: immediate pushing at complete cervical dilation of 10 cm and delayed pushing 90 minutes after complete cervical dilation. This study was a randomized clinical trial in a labor and delivery unit of a not-for-profit community hospital. A sample of 44 nulliparous mothers with continuous epidural anesthesia were studied after random assignment to treatment groups. Subjects were managed with either immediate or delayed pushing during the second stage of labor at the time cervical dilation was complete. The primary outcome measure was the length of pushing during second stage of labor. Secondary outcomes included length of second stage of labor, maternal fatigue and perineal injuries, and fetal heart rate decelerations. Two-tailed, unpaired Student's t-tests and Chi-square analysis were used for data analysis. Level of significance was set at p < .01 following a Bonferroni correction for multiple t-tests. A total of 44 subjects received the study intervention (N = 28 immediate pushing; N = 16 delayed pushing). The delayed pushing group had significantly shorter amount of time spent in pushing compared with the immediate pushing group (38.9 +/- 6.9 vs. 78.7 +/- 7.9 minutes, respectively, p = .002). Maternal fatigue scores, perineal injuries, and fetal heart rate decelerations were similar for both groups. Delaying pushing for up to 90 minutes after complete cervical dilation resulted in a significant decrease in the time mothers spent pushing without a significant increase in total time in second stage of labor.In clinical practice, healthcare providers sometimes resist delaying the onset of pushing after second stage of labor has begun because of a belief it will increase labor time. This study's finding of a 51% reduction in pushing time when mothers delay pushing for up to 90 minutes, with no significant increase in overall time for second stage of labor, disputes that concern.

24 CFR 241.1030 - Mortgage insurance premiums.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Mortgage insurance premiums. 241... Loans-Eligibility Requirements § 241.1030 Mortgage insurance premiums. The lender, upon endorsement of the note, shall pay the Commissioner a first mortgage insurance premium equal to 0.5 percent of the...

24 CFR 241.1030 - Mortgage insurance premiums.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Mortgage insurance premiums. 241... Loans-Eligibility Requirements § 241.1030 Mortgage insurance premiums. The lender, upon endorsement of the note, shall pay the Commissioner a first mortgage insurance premium equal to 0.5 percent of the...

Phenotypic Characterization of Retinoic Acid Differentiated SH-SY5Y Cells by Transcriptional Profiling

PubMed Central

Korecka, Joanna A.; van Kesteren, Ronald E.; Blaas, Eva; Spitzer, Sonia O.; Kamstra, Jorke H.; Smit, August B.; Swaab, Dick F.; Verhaagen, Joost; Bossers, Koen

2013-01-01

Multiple genetic and environmental factors play a role in the development and progression of Parkinson’s disease (PD). The main neuropathological hallmark of PD is the degeneration of dopaminergic (DAergic) neurons in the substantia nigra pars compacta. To study genetic and molecular contributors to the disease process, there is a great need for readily accessible cells with prominent DAergic features that can be used for reproducible in vitro cellular screening. Here, we investigated the molecular phenotype of retinoic acid (RA) differentiated SH-SY5Y cells using genome wide transcriptional profiling combined with gene ontology, transcription factor and molecular pathway analysis. We demonstrated that RA induces a general neuronal differentiation program in SH-SY5Y cells and that these cells develop a predominantly mature DAergic-like neurotransmitter phenotype. This phenotype is characterized by increased dopamine levels together with a substantial suppression of other neurotransmitter phenotypes, such as those for noradrenaline, acetylcholine, glutamate, serotonin and histamine. In addition, we show that RA differentiated SH-SY5Y cells express the dopamine and noradrenalin neurotransmitter transporters that are responsible for uptake of MPP(+), a well known DAergic cell toxicant. MPP(+) treatment alters mitochondrial activity according to its proposed cytotoxic effect in DAergic neurons. Taken together, RA differentiated SH-SY5Y cells have a DAergic-like phenotype, and provide a good cellular screening tool to find novel genes or compounds that affect cytotoxic processes that are associated with PD. PMID:23724009

The SH-SY5Y cell line in Parkinson's disease research: a systematic review.

PubMed

Xicoy, Helena; Wieringa, Bé; Martens, Gerard J M

2017-01-24

Parkinson's disease (PD) is a devastating and highly prevalent neurodegenerative disease for which only symptomatic treatment is available. In order to develop a truly effective disease-modifying therapy, improvement of our current understanding of the molecular and cellular mechanisms underlying PD pathogenesis and progression is crucial. For this purpose, standardization of research protocols and disease models is necessary. As human dopaminergic neurons, the cells mainly affected in PD, are difficult to obtain and maintain as primary cells, current PD research is mostly performed with permanently established neuronal cell models, in particular the neuroblastoma SH-SY5Y lineage. This cell line is frequently chosen because of its human origin, catecholaminergic (though not strictly dopaminergic) neuronal properties, and ease of maintenance. However, there is no consensus on many fundamental aspects that are associated with its use, such as the effects of culture media composition and of variations in differentiation protocols. Here we present the outcome of a systematic review of scientific articles that have used SH-SY5Y cells to explore PD. We describe the cell source, culture conditions, differentiation protocols, methods/approaches used to mimic PD and the preclinical validation of the SH-SY5Y findings by employing alternative cellular and animal models. Thus, this overview may help to standardize the use of the SH-SY5Y cell line in PD research and serve as a future user's guide.

41 CFR 101-25.101-1 - General.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true General. 101-25.101-1 Section 101-25.101-1 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 25-GENERAL 25.1-General Policies...

Effect of americium-241 on luminous bacteria. Role of peroxides.

PubMed

Alexandrova, M; Rozhko, T; Vydryakova, G; Kudryasheva, N

2011-04-01

The effect of americium-241 ((241)Am), an alpha-emitting radionuclide of high specific activity, on luminous bacteria Photobacterium phosphoreum was studied. Traces of (241)Am in nutrient media (0.16-6.67 kBq/L) suppressed the growth of bacteria, but enhanced luminescence intensity and quantum yield at room temperature. Lower temperature (4 °C) increased the time of bacterial luminescence and revealed a stage of bioluminescence inhibition after 150 h of bioluminescence registration start. The role of conditions of exposure the bacterial cells to the (241)Am is discussed. The effect of (241)Am on luminous bacteria was attributed to peroxide compounds generated in water solutions as secondary products of radioactive decay. Increase of peroxide concentration in (241)Am solutions was demonstrated; and the similarity of (241)Am and hydrogen peroxide effects on bacterial luminescence was revealed. The study provides a scientific basis for elaboration of bioluminescence-based assay to monitor radiotoxicity of alpha-emitting radionuclides in aquatic solutions. Copyright © 2011 Elsevier Ltd. All rights reserved.

PUSHing core-collapse simulations to explosion

NASA Astrophysics Data System (ADS)

Fröhlich, C.; Perego, A.; Hempe, M.; Ebinger, K.; Eichler, M.; Casanova, J.; Liebendörfer, M.; Thielemann, F.-K.

2018-01-01

We report on the PUSH method for artificially triggering core-collapse supernova explosions of massive stars in spherical symmetry. The PUSH method increases the energy deposition in the gain region proportionally to the heavy flavor neutrino fluxes.We summarize the parameter dependence of the method and calibrate PUSH to reproduce SN 1987A observables. We identify a best-fit progenitor and set of parameters that fit the explosion properties of SN 1987A, assuming 0.1 M⊙ of fallback. For the explored progenitor range of 18-21 M⊙, we find correlations between explosion properties and the compactness of the progenitor model.

Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research.

PubMed

Cheung, Yuen-Ting; Lau, Way Kwok-Wai; Yu, Man-Shan; Lai, Cora Sau-Wan; Yeung, Sze-Chun; So, Kwok-Fai; Chang, Raymond Chuen-Chung

2009-01-01

Human neuroblastoma SH-SY5Y is a dopaminergic neuronal cell line which has been used as an in vitro model for neurotoxicity experiments. Although the neuroblastoma is usually differentiated by all-trans-retinoic acid (RA), both RA-differentiated and undifferentiated SH-SY5Y cells have been used in neuroscience research. However, the changes in neuronal properties triggered by RA as well as the subsequent responsiveness to neurotoxins have not been comprehensively studied. Therefore, we aim to re-evaluate the differentiation property of RA on this cell line. We hypothesize that modulation of signaling pathways and neuronal properties during RA-mediated differentiation in SH-SY5Y cells can affect their susceptibility to neurotoxins. The differentiation property of RA was confirmed by showing an extensive outgrowth of neurites, increased expressions of neuronal nuclei, neuron specific enolase, synaptophysin and synaptic associated protein-97, and decreased expression of inhibitor of differentiation-1. While undifferentiated SH-SY5Y cells were susceptible to 6-OHDA and MPP+, RA-differentiation conferred SH-SY5Y cells higher tolerance, potentially by up-regulating survival signaling, including Akt pathway as inhibition of Akt removed RA-induced neuroprotection against 6-OHDA. As a result, the real toxicity cannot be revealed in RA-differentiated cells. Therefore, undifferentiated SH-SY5Y is more appropriate for studying neurotoxicity or neuroprotection in experimental Parkinson's disease research.

33 CFR 83.24 - Towing and pushing (Rule 24).

Code of Federal Regulations, 2010 CFR

2010-07-01

... it can best be seen. (b) Pushing vessel and pushed vessel rigidly connected in composite unit. When a pushing vessel and a vessel being pushed ahead are rigidly connected in a composite unit they shall be...). (e) Vessels being towed. A vessel or object other than those referred to in paragraph (g) of this...

18 CFR 385.101 - Applicability (Rule 101).

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Applicability (Rule 101). 385.101 Section 385.101 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES RULES OF PRACTICE AND PROCEDURE Applicability and Definitions § 385.101...

18 CFR 385.101 - Applicability (Rule 101).

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Applicability (Rule 101). 385.101 Section 385.101 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES RULES OF PRACTICE AND PROCEDURE Applicability and Definitions § 385.101...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Girardot, Crystal L.; Harlow, Donald G.

This document identifies 241-U Tank Farm (U Farm) leak causes and locations for the 100 series leaking tanks (241-U-104, 241-U-110, and 241-U-112) identified in RPP-RPT-50097, Rev. 0, Hanford 241-U Farm Leak Inventory Assessment Report. This document satisfies the U-Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

15 CFR 241.2 - Legal standard barrels.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Legal standard barrels. 241.2 Section..., VEGETABLES AND OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.2 Legal standard barrels. (a) Any barrel... form or dimensions, is a legal standard barrel for fruits, vegetables, or other dry commodities other...

15 CFR 241.2 - Legal standard barrels.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Legal standard barrels. 241.2 Section..., VEGETABLES AND OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.2 Legal standard barrels. (a) Any barrel... form or dimensions, is a legal standard barrel for fruits, vegetables, or other dry commodities other...

49 CFR 241.15 - Penalties and other consequences for noncompliance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Penalties and other consequences for noncompliance. 241.15 Section 241.15 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL... OF UNITED STATES RAIL OPERATIONS § 241.15 Penalties and other consequences for noncompliance. (a) Any...

[Length of pushing efforts: pushing is not playing. Reply to the article of C. Le Ray and F. Audibert].

PubMed

Schaal, J-P; Dreyfus, M; Bretelle, F; Carbonne, B; Dupuis, O; Foulhy, C; Goffinet, F; Houfflin-Debarge, V; Langer, B; Martin, A; Mercier, C; Mignon, A; Poulain, P; Simon, A; Teurnier, F; Verspyck, E; Riethmuller, D; Hoffmann, P; Pierre, F

2008-11-01

The aim of this work is to answer constructively to C. Le Ray and F. Audibert who were surprised that the French guidelines recommended an assisted delivery after 30 min pushing, even if the fetal heart rate is reassuring. We first resumed the definition of "second stage of labor", this word including the first phase with no pushing efforts and the second phase with active pushing of the mother. With that definition, the length of the second stage is around 60 min for the primipara and 20 min for the multipara, this length being modified by the use of peridural. We then specified the physiological mechanisms influencing the acidobasic equilibrium during the pushing time. Those mechanisms are difficult to consider because foetal heart rate monitoring is often "lost" during that phase. Altogether, these factors bring incertitude about progressive foetal acidosis and incapacity to diagnose it. Finally, the literature analysis teaches us that increasing the second stage of labor (inactive plus active phases) during the normal pregnancy seems to be at low risk for the foetus within the primiparas, but display a risk for the mother and so might be limited. Comparing the delayed pushing with the immediate pushing only lead us to conclude that delayed pushing is dangerous, as is prolonged second stage. In conclusion, we think that prolonging the second stage of labor is possible but must be by increasing the inactive first phase of the second stage, especially as long as we will not get a noninvasive and reliable method allowing assessing the well-being of the foetus.

Evaluation of MuSyQ land surface albedo based on LAnd surface Parameters VAlidation System (LAPVAS)

NASA Astrophysics Data System (ADS)

Dou, B.; Wen, J.; Xinwen, L.; Zhiming, F.; Wu, S.; Zhang, Y.

2016-12-01

satellite derived Land surface albedo is an essential climate variable which controls the earth energy budget and it can be used in applications such as climate change, hydrology, and numerical weather prediction. However, the accuracy and uncertainty of surface albedo products should be evaluated with a reliable reference truth data prior to applications. A new comprehensive and systemic project of china, called the Remote Sensing Application Network (CRSAN), has been launched recent years. Two subjects of this project is developing a Multi-source data Synergized Quantitative Remote Sensin g Production System ( MuSyQ ) and a Web-based validation system named LAnd surface remote sensing Product VAlidation System (LAPVAS) , which aims to generate a quantitative remote sensing product for ecosystem and environmental monitoring and validate them with a reference validation data and a standard validation system, respectively. Land surface BRDF/albedo is one of product datasets of MuSyQ which has a pentad period with 1km spatial resolution and is derived by Multi-sensor Combined BRDF Inversion ( MCBI ) Model. In this MuSyQ albedo evaluation, a multi-validation strategy is implemented by LAPVAS, including directly and multi-scale validation with field measured albedo and cross validation with MODIS albedo product with different land cover. The results reveal that MuSyQ albedo data with a 5-day temporal resolution is in higher sensibility and accuracy during land cover change period, e.g. snowing. But results without regard to snow or changed land cover, MuSyQ albedo generally is in similar accuracy with MODIS albedo and meet the climate modeling requirement of an absolute accuracy of 0.05.

41 CFR 101-30.101-1 - Civil agency item.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Civil agency item. 101-30.101-1 Section 101-30.101-1 Public Contracts and Property Management Federal Property Management....1-General § 101-30.101-1 Civil agency item. Civil agency item means an item of supply in the supply...

41 CFR 101-30.101-1 - Civil agency item.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 41 Public Contracts and Property Management 2 2011-07-01 2007-07-01 true Civil agency item. 101-30.101-1 Section 101-30.101-1 Public Contracts and Property Management Federal Property Management....1-General § 101-30.101-1 Civil agency item. Civil agency item means an item of supply in the supply...

CO2 Push-Pull Dual (Conjugate) Faults Injection Simulations

DOE Data Explorer

Oldenburg, Curtis (ORCID:0000000201326016); Lee, Kyung Jae; Doughty, Christine; Jung, Yoojin; Borgia, Andrea; Pan, Lehua; Zhang, Rui; Daley, Thomas M.; Altundas, Bilgin; Chugunov, Nikita

2017-07-20

This submission contains datasets and a final manuscript associated with a project simulating carbon dioxide push-pull into a conjugate fault system modeled after Dixie Valley- sensitivity analysis of significant parameters and uncertainty prediction by data-worth analysis. Datasets include: (1) Forward simulation runs of standard cases (push & pull phases), (2) Local sensitivity analyses (push & pull phases), and (3) Data-worth analysis (push & pull phases).

8 CFR 241.3 - Detention of aliens during removal period.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Detention of aliens during removal period. 241.3 Section 241.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS APPREHENSION AND DETENTION OF ALIENS ORDERED REMOVED Post-hearing Detention and Removal § 241.3 Detention of...

8 CFR 241.3 - Detention of aliens during removal period.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Detention of aliens during removal period. 241.3 Section 241.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS APPREHENSION AND DETENTION OF ALIENS ORDERED REMOVED Post-hearing Detention and Removal § 241.3 Detention of...

8 CFR 241.3 - Detention of aliens during removal period.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Detention of aliens during removal period. 241.3 Section 241.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS APPREHENSION AND DETENTION OF ALIENS ORDERED REMOVED Post-hearing Detention and Removal § 241.3 Detention of...

8 CFR 241.3 - Detention of aliens during removal period.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Detention of aliens during removal period. 241.3 Section 241.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS APPREHENSION AND DETENTION OF ALIENS ORDERED REMOVED Post-hearing Detention and Removal § 241.3 Detention of...

8 CFR 241.3 - Detention of aliens during removal period.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Detention of aliens during removal period. 241.3 Section 241.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS APPREHENSION AND DETENTION OF ALIENS ORDERED REMOVED Post-hearing Detention and Removal § 241.3 Detention of...

Pushed Out

ERIC Educational Resources Information Center

Brownstein, Rhonda

2010-01-01

Significant numbers of students are being pushed out of school as a result of "zero tolerance" school discipline policies. While nobody questions the need to keep schools safe, teachers, students, and parents are questioning the methods being used in pursuit of that goal. Zero tolerance policies were initially aimed at making schools safe. The…

ARC-2008-ACD08-0205-069

NASA Image and Video Library

2008-09-16

NASA's 50th Anniversay year. Panel discussion with four of NASA AMES's past center directors on how their tenure effected Ames and NASA. On the projects they pushed for and/or pushed forward and the culture of the center and the agency and how that worked for or against Ames, as well as major contributions of the time made by Ames Research Center. Panel L-R; Hans Mark, Sy Syvertson, Dale Compton, Scott Hubbard and Pete Worden, present director. (Past Directors served for periods from 1969 thru 2006) Sy Syverson posses with his portrait hanging in the hall of NASA Ames Administration Building N-200.

Protective Effect of Edaravone Against Aβ25-35-Induced Mitochondrial Oxidative Damage in SH-SY5Y Cells.

PubMed

Zhang, G-L; Zhang, L; Guo, Y-Y; Ma, Z-L; Wang, H-Y; Li, T; Liu, J; Du, Y; Yao, L; Li, T-T; Du, J-M

2017-05-20

Amyloid-β (Aβ)-induced oxidative stress plays an important role in the pathogenesis of Alzheimer's disease (AD). Recent studies show that Aβ accumulation may lead to mitochondrial oxidative damage. In the present study, we investigated the protective effect of edaravone on mitochondrial damage in SH-SY5Y cells treated with Aβ25-35. SH-SY5Y cells were pre-treated with 20, 40 or 80 μM edaravone before treatment with 25 μM Aβ25-35. After 24h cell culture, cellular apoptosis, intracellular reactive oxygen species (ROS), mitochondrial membrane potential (ΔΨm), ATP levels and mitochondrial morphology were evaluated. SH-SY5Y cells exposed to Aβ25-35 had high levels of apoptosis and ROS; loss of ΔΨm, decreased ATP levels and presence of mitochondrial swelling. However, these effects were significantly inhibited by edaravone pre-treatment. These results indicate that edaravone prevents mitochondria oxidative damage caused by Aβ in SH-SY5Y cells, which suggests that it may have potential clinical application in AD therapy.

SPHK1/sphingosine kinase 1-mediated autophagy differs between neurons and SH-SY5Y neuroblastoma cells.

PubMed

Moruno Manchon, Jose Felix; Uzor, Ndidi-Ese; Finkbeiner, Steven; Tsvetkov, Andrey S

2016-08-02

Although implicated in neurodegeneration, autophagy has been characterized mostly in yeast and mammalian non-neuronal cells. In a recent study, we sought to determine if SPHK1 (sphingosine kinase 1), implicated previously in macroautophagy/autophagy in cancer cells, regulates autophagy in neurons. SPHK1 synthesizes sphingosine-1-phosphate (S1P), a bioactive lipid involved in cell survival. In our study, we discovered that, when neuronal autophagy is pharmacologically stimulated, SPHK1 relocalizes to the endocytic and autophagic organelles. Interestingly, in non-neuronal cells stimulated with growth factors, SPHK1 translocates to the plasma membrane, where it phosphorylates sphingosine to produce S1P. Whether SPHK1 also binds to the endocytic and autophagic organelles in non-neuronal cells upon induction of autophagy has not been demonstrated. Here, we determined if the effect in neurons is operant in the SH-SY5Y neuroblastoma cell line. In both non-differentiated and differentiated SH-SY5Y cells, a short incubation of cells in amino acid-free medium stimulated the formation of SPHK1-positive puncta, as in neurons. We also found that, unlike neurons in which these puncta represent endosomes, autophagosomes, and amphisomes, in SH-SY5Y cells SPHK1 is bound only to the endosomes. In addition, a dominant negative form of SPHK1 was very toxic to SH-SY5Y cells, but cultured primary cortical neurons tolerated it significantly better. These results suggest that autophagy in neurons is regulated by mechanisms that differ, at least in part, from those in SH-SY5Y cells.

Factors affecting the availability of americium-241 to the rice plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adriano, D.C.

1979-11-01

Since there has been no published transuranic uptake data on the rice plant (Oryza sativa L.), greenhouse experiments were conducted to determine the effects of some factors on the uptake of /sup 241/Am by this crop. Results indicate that chelated /sup 241/Am (in the form of americium-241-diethylenetriaminepentaacetic acid) applied to the flood water was markedly taken up by the rice plant, compared to the nonchelated form. However, most of the accumulation of /sup 241/Am occurred in the vegetative parts and only trace amounts, if any, were translocated to the grain. Soil application of /sup 241/Am resulted in much lower uptake.more » Soil amendment with either diethylenetriaminepentaacetic acid (DTPA) or organic matter did not produce a discernible uptake pattern. A synthesis of published data on plant uptake of /sup 241/Am indicates that the concentration ratio (CR, a measure of availability of /sup 241/Am to the plants) values for /sup 241/Am for agricultural crops ranged from 10-/sup 6/ to 10/sup 1/ (from lowest to highest availability). Some factors that appear to influence /sup 241/Am uptake are as follows: plant parts (grain usually having lower CR), chelating agents (DTPA usually increasing the CR), organic matter (inconsistent effects although generally decreasing the CR), and lime (usually decreasing the CR).« less

Kinematics of the field hockey penalty corner push-in.

PubMed

Kerr, Rebecca; Ness, Kevin

2006-01-01

The aims of the study were to determine those variables that significantly affect push-in execution and thereby formulate coaching recommendations specific to the push-in. Two 50 Hz video cameras recorded transverse and longitudinal views of push-in trials performed by eight experienced and nine inexperienced male push-in performers. Video footage was digitized for data analysis of ball speed, stance width, drag distance, drag time, drag speed, centre of massy displacement and segment and stick displacements and velocities. Experienced push-in performers demonstrated a significantly greater (p < 0.05) stance width, a significantly greater distance between the ball and the front foot at the start of the push-in and a significantly faster ball speed than inexperienced performers. In addition, the experienced performers showed a significant positive correlation between ball speed and playing experience and tended to adopt a combination of simultaneous and sequential segment rotation to achieve accuracy and fast ball speed. The study yielded the following coaching recommendations for enhanced push-in performance: maximize drag distance by maximizing front foot-ball distance at the start of the push-in; use a combination of simultaneous and sequential segment rotations to optimise both accuracy and ball speed and maximize drag speed.

33 CFR 157.15 - Slop tanks in tank vessels.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Slop tanks in tank vessels. 157... (CONTINUED) POLLUTION RULES FOR THE PROTECTION OF THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Design, Equipment, and Installation § 157.15 Slop tanks in tank vessels. (a) Number. A...

33 CFR 157.15 - Slop tanks in tank vessels.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Slop tanks in tank vessels. 157... (CONTINUED) POLLUTION RULES FOR THE PROTECTION OF THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Design, Equipment, and Installation § 157.15 Slop tanks in tank vessels. (a) Number. A...

33 CFR 157.15 - Slop tanks in tank vessels.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Slop tanks in tank vessels. 157... (CONTINUED) POLLUTION RULES FOR THE PROTECTION OF THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Design, Equipment, and Installation § 157.15 Slop tanks in tank vessels. (a) Number. A...

33 CFR 157.15 - Slop tanks in tank vessels.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Slop tanks in tank vessels. 157... (CONTINUED) POLLUTION RULES FOR THE PROTECTION OF THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Design, Equipment, and Installation § 157.15 Slop tanks in tank vessels. (a) Number. A...

Production and recovery of Americium-241

DOE Office of Scientific and Technical Information (OSTI.GOV)

Navratil, J.D.

1984-01-01

Americium-241, one of the most useful actinide isotopes, is produced as a by-product of plutonium scrap recovery operations. Rocky Flats (RF) has supplied high-purity americium oxide to the US Department of Energy's Isotope Pool since 1962. Over the years, the evolving separation and purification processes have included such diverse operations as aqueous precipitation, ion exchange, and both molten-salt and organic-solvent extraction. A review is presented of the production and recovery processes of americium-241. 5 references.

41 CFR 101-39.101-1 - Agency cooperation.

Code of Federal Regulations, 2010 CFR

2010-07-01

...-INTERAGENCY FLEET MANAGEMENT SYSTEMS 39.1-Establishment, Modification, and Discontinuance of Interagency Fleet... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Agency cooperation. 101-39.101-1 Section 101-39.101-1 Public Contracts and Property Management Federal Property Management...

41 CFR 101-30.101-14 - Maintenance action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Maintenance action. 101-30.101-14 Section 101-30.101-14 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 30-FEDERAL CATALOG SYSTEM 30...

41 CFR 101-30.101-13 - Management data.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Management data. 101-30.101-13 Section 101-30.101-13 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 30-FEDERAL CATALOG SYSTEM 30...

Tank 40 final sludge batch 9 chemical and fissile radionuclide characterization results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bannochie, C. J.; Kubilius, W. P.; Pareizs, J. M.

A sample of Sludge Batch (SB) 9 was pulled from Tank 40 in order to obtain radionuclide inventory analyses necessary for compliance with the Waste Acceptance Product Specifications (WAPS)i. The SB9 WAPS sample was also analyzed for chemical composition, including noble metals, and fissile constituents, and these results are reported here. These analyses along with the WAPS radionuclide analyses will help define the composition of the sludge in Tank 40 that is fed to the Defense Waste Processing Facility (DWPF) as SB9. At the Savannah River National Laboratory (SRNL), the 3-L Tank 40 SB9 sample was transferred from the shippingmore » container into a 4-L high density polyethylene bottle and solids were allowed to settle. Supernate was then siphoned off and circulated through the shipping container to complete the transfer of the sample. Following thorough mixing of the 3-L sample, a 547 g sub-sample was removed. This sub-sample was then utilized for all subsequent slurry sample preparations. Eight separate aliquots of the slurry were digested, four with HNO3/HCl (aqua regiaii) in sealed Teflon® vessels and four with NaOH/Na2O2 (alkali or peroxide fusioniii) using Zr crucibles. Three Analytical Reference Glass – 1iv (ARG-1) standards were digested along with a blank for each preparation. Each aqua regia digestion and blank was diluted to 1:100 with deionized water and submitted to Analytical Development (AD) for inductively coupled plasma – atomic emission spectroscopy (ICP-AES) analysis, inductively coupled plasma – mass spectrometry (ICP-MS) analysis, atomic absorption spectroscopy (AA) for As and Se, and cold vapor atomic absorption spectroscopy (CV-AA) for Hg. Equivalent dilutions of the alkali fusion digestions and blank were submitted to AD for ICP-AES analysis. Tank 40 SB9 supernate was collected from a mixed slurry sample in the SRNL Shielded Cells and submitted to AD for ICP-AES, ion chromatography (IC), total base/free OH-/other base, total

DOE Office of Scientific and Technical Information (OSTI.GOV)

Girardot, Crystal L.; Harlow, Donald G.

This document identifies 241-T Tank Farm (T Farm) leak causes and locations for the 100 series leaking tanks (241-T-106 and 241-T-111) identified in RPP-RPT-55084, Rev. 0, Hanford 241-T Farm Leak Inventory Assessment Report. This document satisfies the T Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

Morphological Differentiation Towards Neuronal Phenotype of SH-SY5Y Neuroblastoma Cells by Estradiol, Retinoic Acid and Cholesterol.

PubMed

Teppola, Heidi; Sarkanen, Jertta-Riina; Jalonen, Tuula O; Linne, Marja-Leena

2016-04-01

Human SH-SY5Y neuroblastoma cells maintain their potential for differentiation and regression in culture conditions. The induction of differentiation could serve as a strategy to inhibit cell proliferation and tumor growth. Previous studies have shown that differentiation of SH-SY5Y cells can be induced by all-trans-retinoic-acid (RA) and cholesterol (CHOL). However, signaling pathways that lead to terminal differentiation of SH-SY5Y cells are still largely unknown. The goal of this study was to examine in the RA and CHOL treated SH-SY5Y cells the additive impacts of estradiol (E2) and brain-derived neurotrophic factor (BDNF) on cell morphology, cell population growth, synaptic vesicle recycling and presence of neurofilaments. The above features indicate a higher level of neuronal differentiation. Our data show that treatment for 10 days in vitro (DIV) with RA alone or when combined with E2 (RE) or CHOL (RC), but not when combined with BDNF (RB), significantly (p < 0.01) inhibited the cell population growth. Synaptic vesicle recycling, induced by high-K(+) depolarization, was significantly increased in all treatments where RA was included (RE, RC, RB, RCB), and when all agents were added together (RCBE). Specifically, our results show for the first time that E2 treatment can alone increase synaptic vesicle recycling in SH-SY5Y cells. This work contributes to the understanding of the ways to improve suppression of neuroblastoma cells' population growth by inducing maturation and differentiation.

TankSIM: A Cryogenic Tank Performance Prediction Program

NASA Technical Reports Server (NTRS)

Bolshinskiy, L. G.; Hedayat, A.; Hastings, L. J.; Moder, J. P.; Schnell, A. R.; Sutherlin, S. G.

2015-01-01

Accurate prediction of the thermodynamic state of the cryogenic propellants in launch vehicle tanks is necessary for mission planning and successful execution. Cryogenic propellant storage and transfer in space environments requires that tank pressure be controlled. The pressure rise rate is determined by the complex interaction of external heat leak, fluid temperature stratification, and interfacial heat and mass transfer. If the required storage duration of a space mission is longer than the period in which the tank pressure reaches its allowable maximum, an appropriate pressure control method must be applied. Therefore, predictions of the pressurization rate and performance of pressure control techniques in cryogenic tanks are required for development of cryogenic fluid long-duration storage technology and planning of future space exploration missions. This paper describes an analytical tool, Tank System Integrated Model (TankSIM), which can be used for modeling pressure control and predicting the behavior of cryogenic propellant for long-term storage for future space missions. It is written in the FORTRAN 90 language and can be compiled with any Visual FORTRAN compiler. A thermodynamic vent system (TVS) is used to achieve tank pressure control. Utilizing TankSIM, the following processes can be modeled: tank self-pressurization, boiloff, ullage venting, and mixing. Details of the TankSIM program and comparisons of its predictions with test data for liquid hydrogen and liquid methane will be presented in the final paper.

Short Chemical Ischemia Triggers Phosphorylation of eIF2α and Death of SH-SY5Y Cells but not Proteasome Stress and Heat Shock Protein Response in both SH-SY5Y and T98G Cells.

PubMed

Klacanova, Katarina; Pilchova, Ivana; Klikova, Katarina; Racay, Peter

2016-04-01

Both translation arrest and proteasome stress associated with accumulation of ubiquitin-conjugated protein aggregates were considered as a cause of delayed neuronal death after transient global brain ischemia; however, exact mechanisms as well as possible relationships are not fully understood. The aim of this study was to compare the effect of chemical ischemia and proteasome stress on cellular stress responses and viability of neuroblastoma SH-SY5Y and glioblastoma T98G cells. Chemical ischemia was induced by transient treatment of the cells with sodium azide in combination with 2-deoxyglucose. Proteasome stress was induced by treatment of the cells with bortezomib. Treatment of SH-SY5Y cells with sodium azide/2-deoxyglucose for 15 min was associated with cell death observed 24 h after treatment, while glioblastoma T98G cells were resistant to the same treatment. Treatment of both SH-SY5Y and T98G cells with bortezomib was associated with cell death, accumulation of ubiquitin-conjugated proteins, and increased expression of Hsp70. These typical cellular responses to proteasome stress, observed also after transient global brain ischemia, were not observed after chemical ischemia. Finally, chemical ischemia, but not proteasome stress, was in SH-SY5Y cells associated with increased phosphorylation of eIF2α, another typical cellular response triggered after transient global brain ischemia. Our results showed that short chemical ischemia of SH-SY5Y cells is not sufficient to induce both proteasome stress associated with accumulation of ubiquitin-conjugated proteins and stress response at the level of heat shock proteins despite induction of cell death and eIF2α phosphorylation.

30 CFR 241.52 - What if I correct the violation?

Code of Federal Regulations, 2010 CFR

2010-07-01

... § 241.52 What if I correct the violation? The matter will be closed if you correct all of the violations... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What if I correct the violation? 241.52 Section 241.52 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE...

27 CFR 24.229 - Tank car and tank truck requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Tank car and tank truck... BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL WINE Spirits § 24.229 Tank car and tank truck requirements. Railroad tank cars and tank trucks used to transport spirits for use in wine production will be constructed...