Outcomes of complete vs targeted approaches to endoscopic sinus surgery.

PubMed

DeConde, Adam S; Suh, Jeffrey D; Mace, Jess C; Alt, Jeremiah A; Smith, Timothy L

2015-08-01

Functional endoscopic sinus surgery (FESS) was historically predicated on targeted widening of narrow anatomic structures that caused postobstructive persistent sinus inflammation. It is now clear that chronic rhinosinusitis (CRS) is a multifactorial disease with subsets of patients which may require a more extensive surgical approach. This study compares quality-of-life (QOL) and disease severity outcomes after FESS based on the extent of surgical intervention. Participants with CRS were prospectively enrolled into an ongoing, multi-institutional, observational, cohort study. Surgical extent was determined by physician discretion. Participants undergoing bilateral frontal sinusotomy, ethmoidectomy, maxillary antrostomy, and sphenoidotomy were considered to have undergone "complete" surgery, whereas all other participants were categorized as receiving "targeted" surgery. Improvement was evaluated between surgical subgroups with at least 6-month follow-up using the 22-item Sino-Nasal Outcome Test (SNOT-22) and the Brief Smell Inventory Test (B-SIT). A total of 311 participants met inclusion criteria with 147 subjects undergoing complete surgery and 164 targeted surgery. A higher prevalence of asthma, acetylsalicylic acid (ASA) sensitivity, nasal polyposis, and a history of prior sinus surgery (p ≤ 0.002) was present in participants undergoing complete surgery. Mean improvement in SNOT-22 (28.1 ± 21.9 vs 21.9 ± 20.6; p = 0.011) and B-SIT (0.8 ± 3.1 vs 0.2 ± 2.4; p = 0.005) was greater in subjects undergoing complete surgery. Regression models demonstrated a 5.9 ± 2.5 greater relative mean improvement on SNOT-22 total scores with complete surgery over targeted approaches (p = 0.016). Complete surgery was an independent predictor of greater postoperative SNOT-22 score improvement, yet did not achieve clinical significance. Further study is needed to determine the optimal surgical extent. © 2015 ARS-AAOA, LLC.

The complete chloroplast genome sequence of date palm (Phoenix dactylifera L.).

PubMed

Yang, Meng; Zhang, Xiaowei; Liu, Guiming; Yin, Yuxin; Chen, Kaifu; Yun, Quanzheng; Zhao, Duojun; Al-Mssallem, Ibrahim S; Yu, Jun

2010-09-15

Date palm (Phoenix dactylifera L.), a member of Arecaceae family, is one of the three major economically important woody palms--the two other palms being oil palm and coconut tree--and its fruit is a staple food among Middle East and North African nations, as well as many other tropical and subtropical regions. Here we report a complete sequence of the data palm chloroplast (cp) genome based on pyrosequencing. After extracting 369,022 cp sequencing reads from our whole-genome-shotgun data, we put together an assembly and validated it with intensive PCR-based verification, coupled with PCR product sequencing. The date palm cp genome is 158,462 bp in length and has a typical quadripartite structure of the large (LSC, 86,198 bp) and small single-copy (SSC, 17,712 bp) regions separated by a pair of inverted repeats (IRs, 27,276 bp). Similar to what has been found among most angiosperms, the date palm cp genome harbors 112 unique genes and 19 duplicated fragments in the IR regions. The junctions between LSC/IRs and SSC/IRs show different features of sequence expansion in evolution. We identified 78 SNPs as major intravarietal polymorphisms within the population of a specific cp genome, most of which were located in genes with vital functions. Based on RNA-sequencing data, we also found 18 polycistronic transcription units and three highly expression-biased genes--atpF, trnA-UGC, and rrn23. Unlike most monocots, date palm has a typical cp genome similar to that of tobacco--with little rearrangement and gene loss or gain. High-throughput sequencing technology facilitates the identification of intravarietal variations in cp genomes among different cultivars. Moreover, transcriptomic analysis of cp genes provides clues for uncovering regulatory mechanisms of transcription and translation in chloroplasts.

The Complete Chloroplast Genome Sequence of Date Palm (Phoenix dactylifera L.)

PubMed Central

Yang, Meng; Zhang, Xiaowei; Liu, Guiming; Yin, Yuxin; Chen, Kaifu; Yun, Quanzheng; Zhao, Duojun; Al-Mssallem, Ibrahim S.; Yu, Jun

2010-01-01

Background Date palm (Phoenix dactylifera L.), a member of Arecaceae family, is one of the three major economically important woody palms—the two other palms being oil palm and coconut tree—and its fruit is a staple food among Middle East and North African nations, as well as many other tropical and subtropical regions. Here we report a complete sequence of the data palm chloroplast (cp) genome based on pyrosequencing. Methodology/Principal Findings After extracting 369,022 cp sequencing reads from our whole-genome-shotgun data, we put together an assembly and validated it with intensive PCR-based verification, coupled with PCR product sequencing. The date palm cp genome is 158,462 bp in length and has a typical quadripartite structure of the large (LSC, 86,198 bp) and small single-copy (SSC, 17,712 bp) regions separated by a pair of inverted repeats (IRs, 27,276 bp). Similar to what has been found among most angiosperms, the date palm cp genome harbors 112 unique genes and 19 duplicated fragments in the IR regions. The junctions between LSC/IRs and SSC/IRs show different features of sequence expansion in evolution. We identified 78 SNPs as major intravarietal polymorphisms within the population of a specific cp genome, most of which were located in genes with vital functions. Based on RNA-sequencing data, we also found 18 polycistronic transcription units and three highly expression-biased genes—atpF, trnA-UGC, and rrn23. Conclusions Unlike most monocots, date palm has a typical cp genome similar to that of tobacco—with little rearrangement and gene loss or gain. High-throughput sequencing technology facilitates the identification of intravarietal variations in cp genomes among different cultivars. Moreover, transcriptomic analysis of cp genes provides clues for uncovering regulatory mechanisms of transcription and translation in chloroplasts. PMID:20856810

77 FR 20749 - Investment Company Advertising: Target Date Retirement Fund Names and Marketing

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-06

... Names and Marketing AGENCY: Securities and Exchange Commission. ACTION: Proposed rule; reopening of... use of the fund's name in marketing materials; require marketing materials for target date retirement... a statement that would highlight the fund's final asset allocation; require a statement in marketing...

Dating conflicts: rethinking dating violence and youth conflict.

PubMed

Adelman, Madelaine; Kil, Sang Hea

2007-12-01

Dating couples are tied to each other's friends who have expectations about dating, such as who constitutes an acceptable date and how to balance friendship and dating. We explore the place of friends in dating conflicts (i.e., conflicts and violence associated with heterosexual teen dating) and ask: (a) How are friends implicated in teen dating/violence not only as targets or confidants, but also as participants in conflict that stems from their friends' relationships, and (b) in what ways do dating conflicts conserve or challenge the power of gender and sexual conformity that underlies heterosexual dating and dating violence?

49 CFR 381.510 - May the FMCSA end a pilot program before its scheduled completion date?

Code of Federal Regulations, 2010 CFR

2010-10-01

... achieving a level of safety that is at least equivalent to the level of safety that would be achieved by... 49 Transportation 5 2010-10-01 2010-10-01 false May the FMCSA end a pilot program before its... Pilot Programs § 381.510 May the FMCSA end a pilot program before its scheduled completion date? The...

Assessing the effects of Families for Safe Dates, a family-based teen dating abuse prevention program.

PubMed

Foshee, Vangie A; McNaughton Reyes, Heath Luz; Ennett, Susan T; Cance, Jessica D; Bauman, Karl E; Bowling, J Michael

2012-10-01

To examine the effects of a family-based teen dating abuse prevention program, Families for Safe Dates, primarily on outcomes related to testing the conceptual underpinnings of the program including (1) factors motivating and facilitating caregiver engagement in teen dating abuse prevention activities, and 2) risk factors for teen dating abuse, and secondarily on dating abuse behaviors. Families were recruited nationwide using listed telephone numbers. Caregivers and teens completed baseline and 3-month follow-up telephone interviews (n = 324). Families randomly allocated to treatment condition received the Families for Safe Dates program including six mailed activity booklets followed-up by health educator telephone calls. There were significant (<.05) treatment effects in hypothesized directions on most of the factors motivating and facilitating caregiver engagement in teen dating abuse prevention activities including caregiver perceived severity of dating abuse, response efficacy for preventing dating abuse, self-efficacy for talking about dating abuse, knowledge of dating abuse, acceptance of dating abuse, communication skills with the teen, and belief in the importance of involvement in their male (but not female) teen's dating. The latter effect was the only one moderated by sex of the teen. The targeted risk factor affected by the program was teen acceptance of dating abuse. Treatment was also significantly associated with less physical dating abuse victimization. Modifications to the program are warranted, but overall, the findings are very favorable for the first family-based teen dating abuse prevention program to be evaluated. Copyright © 2012 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

29 mm Diameter Target Test Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Woloshun, Keith Albert; Olivas, Eric Richard; Dale, Gregory E.

After numerous delays, the test of the 29 mm diameter target was conducted on 8/18/2017. The complete target design report, dated 8/15/2016, is reproduced below for completeness. This describes in detail the 10 disk target with varying thickness disks. The report presents and discusses the test results. In brief summary, there appears to have been multiple instrumentation errors. Measured temperatures, pressures and IR camera window temperature measurement are all suspect. All tests were done at 35 MeV, with 171 μA current, or 6 kW of beam power.

Signaling completion of a message transfer from an origin compute node to a target compute node

DOEpatents

Blocksome, Michael A [Rochester, MN; Parker, Jeffrey J [Rochester, MN

2011-05-24

Signaling completion of a message transfer from an origin node to a target node includes: sending, by an origin DMA engine, an RTS message, the RTS message specifying an application message for transfer to the target node from the origin node; receiving, by the origin DMA engine, a remote get message containing a data descriptor for the message and a completion notification descriptor, the completion notification descriptor specifying a local direct put transfer operation for transferring data locally on the origin node; inserting, by the origin DMA engine in an injection FIFO buffer, the data descriptor followed by the completion notification descriptor; transferring, by the origin DMA engine to the target node, the message in dependence upon the data descriptor; and notifying, by the origin DMA engine, the application that transfer of the message is complete in dependence upon the completion notification descriptor.

Psychological abuse, mental health, and acceptance of dating violence among adolescents

PubMed Central

Temple, Jeff R.; Choi, Hye Jeong; Elmquist, JoAnna; Hecht, Michael; Miller-Day, Michelle; Stuart, Gregory L.; Brem, Meagan; Wolford-Clevenger, Caitlin

2016-01-01

Purpose Existing literature indicates that acceptance of dating violence is a significant and robust risk factor for psychological dating abuse perpetration. Past work also indicates a significant relationship between psychological dating abuse perpetration and poor mental health. However, no known research has examined the relationship between acceptance of dating violence, perpetration of dating abuse, and mental health. In addition to exploring this complex relationship, the current study examines whether psychological abuse perpetration mediates the relationship between acceptance of dating violence and mental health (i.e., internalizing symptoms of depression, anxiety, and hostility). Methods Three waves of longitudinal data were obtained from 1,042 ethnically diverse high school students in Texas. Participants completed assessments of psychological dating abuse perpetration, acceptance of dating violence, and internalizing symptoms (hostility, and symptoms of anxiety and depression). Results As predicted, results indicated that perpetration of psychological abuse was significantly associated with acceptance of dating violence and all internalizing symptoms. Furthermore, psychological abuse mediated the relationship between acceptance of dating violence and internalizing symptoms. Conclusions Findings from the current study suggest that acceptance of dating violence is an important target for the prevention of dating violence and related emotional distress. Implications and Contribution Study findings indicate that perpetration of psychological abuse is significantly associated with acceptance of dating violence and select mental health variables (i.e., anxiety, depression, hostility). Moreover, psychological abuse perpetration mediated the relationship between acceptance of dating violence and internalizing symptoms. To be effective in preventing mental health problems, interventions may benefit from targeting acceptance and perpetration of dating violence

Signaling completion of a message transfer from an origin compute node to a target compute node

DOEpatents

Blocksome, Michael A [Rochester, MN

2011-02-15

Signaling completion of a message transfer from an origin node to a target node includes: sending, by an origin DMA engine, an RTS message, the RTS message specifying an application message for transfer to the target node from the origin node; receiving, by the origin DMA engine, a remote get message containing a data descriptor for the message and a completion notification descriptor, the completion notification descriptor specifying a local memory FIFO data transfer operation for transferring data locally on the origin node; inserting, by the origin DMA engine in an injection FIFO buffer, the data descriptor followed by the completion notification descriptor; transferring, by the origin DMA engine to the target node, the message in dependence upon the data descriptor; and notifying, by the origin DMA engine, the application that transfer of the message is complete in dependence upon the completion notification descriptor.

Up-Dating: Ratings of Perceived Dating Success Are Better Online than Offline.

PubMed

Fullwood, Chris; Attrill-Smith, Alison

2018-01-01

The primary aims of this study were to test whether perceived dating success would differ between offline and online zero-acquaintance dating contexts and to investigate the role that self-esteem might play in these evaluations. Participants were presented with the same photos of targets in either an offline or online dating scenario and rated their chances of dating success along with their perceptions of how attractive they thought the target would consider them. Higher self-esteem individuals believed they would be rated as more attractive. There was an overall perception that, irrespective of self-esteem level, meeting online would lead to better chances of dating success. These findings are considered in relation to an increased ability to more precisely manage impressions and develop an image of the self which would be evaluated more positively online.

Molecular phylogenetic and dating analysis of pierid butterfly species using complete mitochondrial genomes.

PubMed

Cao, Y; Hao, J S; Sun, X Y; Zheng, B; Yang, Q

2016-12-02

Pieridae is a butterfly family whose evolutionary history is poorly understood. Due to the difficulties in identifying morphological synapomorphies within the group and the scarcity of the fossil records, only a few studies on higher phylogeny of Pieridae have been reported to date. In this study, we describe the complete mitochondrial genomes of four pierid butterfly species (Aporia martineti, Aporia hippia, Aporia bieti, and Mesapia peloria), in order to better characterize the pierid butterfly mitogenomes and perform the phylogenetic analyses using all available mitogenomic sequence data (13PCGs, rRNAs, and tRNAs) from the 18 pierid butterfly species comprising the three main subfamilies (Dismorphiinae, Coliadinae and Pierinae). Our analysis shows that the four new mitogenomes share similar features with other known pierid mitogenomes in gene order and organization. Phylogenetic analyses by maximum likelihood and Bayesian inference show that the pierid higher-level relationship is: Dismorphiinae + (Coliadinae + Pierinae), which corroborates the results of some previous molecular and morphological studies. However, we found that the Hebomoia and Anthocharis make a sister group, supporting the traditional tribe Anthocharidini; in addition, the Mesapia peloria was shown to be clustered within the Aporia group, suggesting that the genus Mesapia should be reduced to the taxonomic status of subgenus. Our molecular dating analysis indicates that the family Pieridae began to diverge during the Late Cretaceous about 92 million years ago (mya), while the subfamily Pierinae diverged from the Coliadinae at about 86 mya (Late Cretaceous).

Witnessing Interparental Violence and Acceptance of Dating Violence as Predictors for Teen Dating Violence Victimization.

PubMed

Karlsson, Marie E; Temple, Jeff R; Weston, Rebecca; Le, Vi Donna

2016-04-01

We examined the association between witnessing interparental violence, attitudes about dating violence, and physical and psychological teen dating violence (TDV) victimization. Participants were 918 teens with dating experience. Witnessing interparental violence and acceptance of dating violence were significant predictors of TDV victimization. Acceptance of dating violence was also a partial mediator between witnessing interparental violence and TDV victimization. Witnessing mother-to-father violence and acceptance of female-perpetrated violence were the most consistent predictors. TDV programs aiming to prevent victimization could benefit from targeting youth exposed to father-to-mother and mother-to-father violence, targeting attitudes about violence, and tailoring interventions to gender-specific risk factors. © The Author(s) 2015.

Psychological Abuse, Mental Health, and Acceptance of Dating Violence Among Adolescents.

PubMed

Temple, Jeff R; Choi, Hye Jeong; Elmquist, JoAnna; Hecht, Michael; Miller-Day, Michelle; Stuart, Gregory L; Brem, Meagan; Wolford-Clevenger, Caitlin

2016-08-01

Existing literature indicates that acceptance of dating violence is a significant and robust risk factor for psychological dating abuse perpetration. Past work also indicates a significant relationship between psychological dating abuse perpetration and poor mental health. However, no known research has examined the relationship between acceptance of dating violence, perpetration of dating abuse, and mental health. In addition to exploring this complex relationship, the present study examines whether psychological abuse perpetration mediates the relationship between acceptance of dating violence and mental health (i.e., internalizing symptoms of depression, anxiety, and hostility). Three waves of longitudinal data were obtained from 1,042 ethnically diverse high school students in Texas. Participants completed assessments of psychological dating abuse perpetration, acceptance of dating violence, and internalizing symptoms (hostility and symptoms of anxiety and depression). As predicted, results indicated that perpetration of psychological abuse was significantly associated with acceptance of dating violence and all internalizing symptoms. Furthermore, psychological abuse mediated the relationship between acceptance of dating violence and internalizing symptoms. Findings from the present study suggest that acceptance of dating violence is an important target for the prevention of dating violence and related emotional distress. Copyright © 2016 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

Sex Role and Dating Orientation.

ERIC Educational Resources Information Center

McCabe, M. P.; Collins, J. K.

1979-01-01

Male and female subjects from three age groups completed questionnaires on sex roles and dating orientations. Males approached dating from both a psychoaffectional and psychobiological orientation, while females approached it from a psychoaffectional orientation. Significant differences were found in dating attitudes between male and female…

20 CFR 404.630 - Use of date of written statement as filing date.

Code of Federal Regulations, 2014 CFR

2014-04-01

... contacts us through the Internet by completing and transmitting the Personal Identification Information data on the Internet Social Security Benefit Application to us, we will use the date of the... date. 404.630 Section 404.630 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE...

20 CFR 404.630 - Use of date of written statement as filing date.

Code of Federal Regulations, 2010 CFR

2010-04-01

... contacts us through the Internet by completing and transmitting the Personal Identification Information data on the Internet Social Security Benefit Application to us, we will use the date of the... date. 404.630 Section 404.630 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE...

20 CFR 404.630 - Use of date of written statement as filing date.

Code of Federal Regulations, 2012 CFR

2012-04-01

... contacts us through the Internet by completing and transmitting the Personal Identification Information data on the Internet Social Security Benefit Application to us, we will use the date of the... date. 404.630 Section 404.630 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE...

20 CFR 404.630 - Use of date of written statement as filing date.

Code of Federal Regulations, 2013 CFR

2013-04-01

... contacts us through the Internet by completing and transmitting the Personal Identification Information data on the Internet Social Security Benefit Application to us, we will use the date of the... date. 404.630 Section 404.630 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE...

Phylogeny and dating of divergences within the genus Thymallus (Salmonidae: Thymallinae) using complete mitochondrial genomes.

PubMed

Ma, Bo; Jiang, Haiying; Sun, Peng; Chen, Jinping; Li, Linmiao; Zhang, Xiujuan; Yuan, Lihong

2016-09-01

The genus Thymallus has attracted increasing attention in recent years because of its sharp demographic decline. In this study, we reported four complete mitochondrial genomes in the Thymallus genus: Baikal-Lena grayling (T. arcticus baicalolenensis), lower Amur grayling (T. tugarinae), Yalu grayling (T. a. yaluensis), and Mongolian grayling (T. brevirostris). The total length of the four new grayling mtDNAs ranged from 16 658 to 16 663 bp, all of which contained 13 protein-coding genes, 22 tRNA genes, two rRNA genes, and one control region. The results suggested that mitochondrial genomes could be a powerful marker for resolving the phylogeny within Thymallinae. Our study validated that the Yalu grayling should be a synonym of the Amur grayling (T. grubii) at the whole mitogenome level. The phylogenetic and dating analyses placed the Amur grayling at the deepest divergence node within Thymallus, diverging at ∼14.95 Ma. The lower Amur grayling diverged at the next deepest node (∼12.14 Ma). This was followed by T. thymallus, which diverged at ∼9.27 Ma. The Mongolian grayling and the ancestor of the sister species, T. arcticus and T. arcticus baicalolenensis, diverged at ∼7.79 Ma, with T. arcticus and T. arcticus baicalolenensis separating at ∼6.64 Ma. Our study provides far better resolution of the phylogenetic relationships and divergence dates of graylings than previous studies.

Validating An Analytic Completeness Model for Kepler Target Stars Based on Flux-level Transit Injection Experiments

NASA Astrophysics Data System (ADS)

Catanzarite, Joseph; Burke, Christopher J.; Li, Jie; Seader, Shawn; Haas, Michael R.; Batalha, Natalie; Henze, Christopher; Christiansen, Jessie; Kepler Project, NASA Advanced Supercomputing Division

2016-06-01

The Kepler Mission is developing an Analytic Completeness Model (ACM) to estimate detection completeness contours as a function of exoplanet radius and period for each target star. Accurate completeness contours are necessary for robust estimation of exoplanet occurrence rates.The main components of the ACM for a target star are: detection efficiency as a function of SNR, the window function (WF) and the one-sigma depth function (OSDF). (Ref. Burke et al. 2015). The WF captures the falloff in transit detection probability at long periods that is determined by the observation window (the duration over which the target star has been observed). The OSDF is the transit depth (in parts per million) that yields SNR of unity for the full transit train. It is a function of period, and accounts for the time-varying properties of the noise and for missing or deweighted data.We are performing flux-level transit injection (FLTI) experiments on selected Kepler target stars with the goal of refining and validating the ACM. “Flux-level” injection machinery inserts exoplanet transit signatures directly into the flux time series, as opposed to “pixel-level” injection, which inserts transit signatures into the individual pixels using the pixel response function. See Jie Li's poster: ID #2493668, "Flux-level transit injection experiments with the NASA Pleiades Supercomputer" for details, including performance statistics.Since FLTI is affordable for only a small subset of the Kepler targets, the ACM is designed to apply to most Kepler target stars. We validate this model using “deep” FLTI experiments, with ~500,000 injection realizations on each of a small number of targets and “shallow” FLTI experiments with ~2000 injection realizations on each of many targets. From the results of these experiments, we identify anomalous targets, model their behavior and refine the ACM accordingly.In this presentation, we discuss progress in validating and refining the ACM, and we

Substance use as a longitudinal predictor of the perpetration of teen dating violence.

PubMed

Temple, Jeff R; Shorey, Ryan C; Fite, Paula; Stuart, Gregory L; Le, Vi Donna

2013-04-01

The prevention of teen dating violence is a major public health priority. However, the dearth of longitudinal studies makes it difficult to develop programs that effectively target salient risk factors. Using a school-based sample of ethnically diverse adolescents, this longitudinal study examined whether substance use (alcohol, marijuana, and hard drugs) and exposure to parental violence predicted the perpetration of physical dating violence over time. 1,042 9th and 10th grade high schools students were recruited and assessed in the spring of 2010, and 93 % of the original sample completed the 1-year follow-up in the spring of 2011. Participants who had begun dating at the initial assessment and who self-identified as African American (n = 263; 32 %), Caucasian (n = 272; 33 %), or Hispanic (n = 293; 35 %) were included in the current analyses (n = 828; 55 % female). Slightly more than half of the adolescents who perpetrated dating violence at baseline reported past year dating violence at follow-up, relative to only 11 % of adolescents who did not report perpetrating dating violence at baseline. Structural equation modeling revealed that the use of alcohol and hard drugs at baseline predicted the future perpetration of physical dating violence, even after accounting for the effects of baseline dating violence and exposure to interparental violence. Despite differences in the prevalence of key variables between males and females, the longitudinal associations did not vary by gender. With respect to race, exposure to mother-to-father violence predicted the perpetration of dating violence among Caucasian adolescents. Findings from the current study indicate that targeting substance use, and potentially youth from violent households, may be viable approaches to preventing the perpetration of teen dating violence.

Substance Use as a Longitudinal Predictor of the Perpetration of Teen Dating Violence

PubMed Central

Shorey, Ryan C.; Fite, Paula; Stuart, Gregory; Le, Vi Donna

2013-01-01

The prevention of teen dating violence is a major public health priority. However, the dearth of longitudinal studies makes it difficult to develop programs that effectively target salient risk factors. Using a school-based sample of ethnically diverse adolescents, this longitudinal study examined whether substance use (alcohol, marijuana, and hard drugs) and exposure to parental violence predicted the perpetration of physical dating violence over time. 1,042 9th and 10th grade high schools students were recruited and assessed in the spring of 2010, and 93% of the original sample completed the 1-year follow-up in the spring of 2011. Participants who had begun dating at the initial assessment and who self-identified as African American (n = 263; 32%), Caucasian (n = 272; 33%), or Hispanic (n = 293; 35%) were included in the current analyses (n = 828; 55% female). Slightly more than half of the adolescents who perpetrated dating violence at baseline reported past year dating violence at follow-up, relative to only 11% of adolescents who did not report perpetrating dating violence at baseline. Structural equation modeling revealed that the use of alcohol and hard drugs at baseline predicted the future perpetration of physical dating violence, even after accounting for the effects of baseline dating violence and exposure to interparental violence. Despite differences in the prevalence of key variables between males and females, the longitudinal associations did not vary by gender. With respect to race, exposure to mother-to-father violence predicted the perpetration of dating violence among Caucasian adolescents. Findings from the current study indicate that targeting substance use, and potentially youth from violent households, may be viable approaches to preventing the perpetration of teen dating violence. PMID:23187699

A Longitudinal Investigation of Heavy Drinking and Physical Dating Violence in Men and Women

PubMed Central

Stappenbeck, Cynthia A.; Fromme, Kim

2010-01-01

Examinations of heavy drinking and dating violence have typically focused on either female victimization or male perpetration; yet recent findings indicate that mutual aggression is the most common pattern of dating violence. The current study investigated the relation between heavy drinking and dating violence for both men and women. Participants (N = 2,247) completed surveys that assessed their heavy drinking and dating violence frequency across the first three years of college. Findings indicated that heavy drinking and dating violence were both relatively stable across time for men and women, but the relation between heavy drinking and dating violence differed by gender. For men, heavy drinking and dating violence were concurrently associated during their freshman year (Year 1), whereas for women heavy drinking during sophomore year (Year 2) predicted dating violence in their junior year (Year 3). In addition to providing educational material on healthy relationships and conflict resolution techniques, intervention efforts should target both heavy drinking and dating violence for men during or prior to their freshman year of college, whereas women may primarily benefit from efforts to reduce their heavy drinking. PMID:20079971

The effects of the evidence-based Safe Dates dating abuse prevention program on other youth violence outcomes.

PubMed

Foshee, Vangie A; Reyes, Luz McNaughton; Agnew-Brune, Christine B; Simon, Thomas R; Vagi, Kevin J; Lee, Rosalyn D; Suchindran, Chiravath

2014-12-01

In response to recent calls for programs that can prevent multiple types of youth violence, the current study examined whether Safe Dates, an evidence-based dating violence prevention program, was effective in preventing other forms of youth violence. Using data from the original Safe Dates randomized controlled trial, this study examined (1) the effectiveness of Safe Dates in preventing peer violence victimization and perpetration and school weapon carrying 1 year after the intervention phase was completed and (2) moderation of program effects by the sex or race/ethnicity of the adolescent. Ninety percent (n = 1,690) of the eighth and ninth graders who completed baseline questionnaires completed the 1-year follow-up assessment. The sample was 51 % female and 26 % minority (of whom 69 % was black and 31 % was of another minority race/ethnicity). There were no baseline treatment group differences in violence outcomes. Treatment condition was significantly associated with peer violence victimization and school weapon carrying at follow-up; there was 12 % less victimization and 31 % less weapon carrying among those exposed to Safe Dates than those among controls. Treatment condition was significantly associated with perpetration among the minority but not among white adolescents; there was 23 % less violence perpetration among minority adolescents exposed to Safe Dates than that among controls. The observed effect sizes were comparable with those of other universal school-based youth violence prevention programs. Implementing Safe Dates may be an efficient way of preventing multiple types of youth violence.

Bullying Predicts Reported Dating Violence and Observed Qualities in Adolescent Dating Relationships.

PubMed

Ellis, Wendy E; Wolfe, David A

2015-10-01

The relationship between reported bullying, reported dating violence, and dating relationship quality measured through couple observations was examined. Given past research demonstrating similarity between peer and dating contexts, we expected that bullying would predict negative dating experiences. Participants with dating experience (n = 585; 238 males, M(age) = 15.06) completed self-report assessments of bullying and dating violence perpetration and victimization. One month later, 44 opposite-sex dyads (M(age) = 15.19) participated in behavioral observations. In 10-min sessions, couples were asked to rank and discuss areas of relationship conflict while being video-recorded. Qualities of the relationship were later coded by trained observers. Regression analysis revealed that bullying positively predicted dating violence perpetration and victimization. Self-reported bullying also predicted observations of lower relationship support and higher withdrawal. Age and gender interactions further qualified these findings. The bullying of boys, but not girls, was significantly related to dating violence perpetration. Age interactions showed that bullying was positively predictive of dating violence perpetration and victimization for older, but not younger adolescents. Positive affect was also negatively predicted by bullying, but only for girls. These findings add to the growing body of evidence that adolescents carry forward strategies learned in the peer context to their dating relationships. © The Author(s) 2014.

Emotion Regulation Difficulties Moderate the Association Between Heavy Episodic Drinking and Dating Violence Perpetration Among College Men

PubMed Central

Stappenbeck, Cynthia A.; Davis, Kelly Cue; Cherf, Nicholas; Gulati, Natasha K.; Kajumulo, Kelly F.

2017-01-01

Because of high rates of heavy drinking and dating violence (psychological or physical aggression toward a dating partner) among college men, we examined whether emotion regulation difficulties moderated the association between heavy drinking and dating violence perpetration. One hundred and fifty-eight men were recruited from a large northwestern US university between April 2014 and August 2014. Participants completed an online survey that assessed their emotion regulation difficulties as well as their past year history of heavy episodic drinking (HED; consuming 5+ drinks in 2 hours) and dating violence perpetration. Generalized linear models revealed that the positive association between HED and dating violence perpetration was stronger for men with greater impulse control difficulties and for those who reported limited access to emotion regulation strategies. In addition to continued efforts to reduce heavy drinking among college men, interventions targeting emotion regulation difficulties should be incorporated into standard dating violence intervention and prevention efforts to further reduce the likelihood of dating violence perpetration in this population. PMID:29147076

Emotion Regulation Difficulties Moderate the Association Between Heavy Episodic Drinking and Dating Violence Perpetration Among College Men.

PubMed

Stappenbeck, Cynthia A; Davis, Kelly Cue; Cherf, Nicholas; Gulati, Natasha K; Kajumulo, Kelly F

2016-01-01

Because of high rates of heavy drinking and dating violence (psychological or physical aggression toward a dating partner) among college men, we examined whether emotion regulation difficulties moderated the association between heavy drinking and dating violence perpetration. One hundred and fifty-eight men were recruited from a large northwestern US university between April 2014 and August 2014. Participants completed an online survey that assessed their emotion regulation difficulties as well as their past year history of heavy episodic drinking (HED; consuming 5+ drinks in 2 hours) and dating violence perpetration. Generalized linear models revealed that the positive association between HED and dating violence perpetration was stronger for men with greater impulse control difficulties and for those who reported limited access to emotion regulation strategies. In addition to continued efforts to reduce heavy drinking among college men, interventions targeting emotion regulation difficulties should be incorporated into standard dating violence intervention and prevention efforts to further reduce the likelihood of dating violence perpetration in this population.

36 CFR 223.47 - Date of completion of permanent road construction.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., DEPARTMENT OF AGRICULTURE SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER, SPECIAL FOREST PRODUCTS, AND FOREST BOTANICAL PRODUCTS Timber Sale Contracts Contract Conditions and Provisions § 223.47 Date of... obligations as set forth in the Notice of Sale shall be incorporated into the timber sale contract. (b) This...

One Bacterial Cell, One Complete Genome

DOE Office of Scientific and Technical Information (OSTI.GOV)

Woyke, Tanja; Tighe, Damon; Mavrommatis, Konstantinos

2010-04-26

While the bulk of the finished microbial genomes sequenced to date are derived from cultured bacterial and archaeal representatives, the vast majority of microorganisms elude current culturing attempts, severely limiting the ability to recover complete or even partial genomes from these environmental species. Single cell genomics is a novel culture-independent approach, which enables access to the genetic material of an individual cell. No single cell genome has to our knowledge been closed and finished to date. Here we report the completed genome from an uncultured single cell of Candidatus Sulcia muelleri DMIN. Digital PCR on single symbiont cells isolated frommore » the bacteriome of the green sharpshooter Draeculacephala minerva bacteriome allowed us to assess that this bacteria is polyploid with genome copies ranging from approximately 200?900 per cell, making it a most suitable target for single cell finishing efforts. For single cell shotgun sequencing, an individual Sulcia cell was isolated and whole genome amplified by multiple displacement amplification (MDA). Sanger-based finishing methods allowed us to close the genome. To verify the correctness of our single cell genome and exclude MDA-derived artifacts, we independently shotgun sequenced and assembled the Sulcia genome from pooled bacteriomes using a metagenomic approach, yielding a nearly identical genome. Four variations we detected appear to be genuine biological differences between the two samples. Comparison of the single cell genome with bacteriome metagenomic sequence data detected two single nucleotide polymorphisms (SNPs), indicating extremely low genetic diversity within a Sulcia population. This study demonstrates the power of single cell genomics to generate a complete, high quality, non-composite reference genome within an environmental sample, which can be used for population genetic analyzes.« less

Radiocarbon dating of terrestrial carbonates

USGS Publications Warehouse

Pigati, Jeffrey S.; Rink, W. Jack; Thompson, Jeroen

2014-01-01

Terrestrial carbonates encompass a wide range of materials that potentially could be used for radiocarbon (14C) dating. Biogenic carbonates, including shells and tests of terrestrial and aquatic gastropods, bivalves, ostracodes, and foraminifera, are preserved in a variety of late Quaternary deposits and may be suitable for 14C dating. Primary calcareous deposits (marls, tufa, speleothems) and secondary carbonates (rhizoliths, fracture fill, soil carbonate) may also be targeted for dating when conditions are favorable. This chapter discusses issues that are commonly encountered in 14C dating of terrestrial carbonates, including isotopic disequilibrium and open-system behavior, as well as methods used to determine the reliability of ages derived from these materials. Recent methodological advancements that may improve the accuracy and precision of 14C ages of terrestrial carbonates are also highlighted.

Trait Anger and Partner-Specific Anger Management Moderate the Temporal Association Between Alcohol Use and Dating Violence.

PubMed

Shorey, Ryan C; McNulty, James K; Moore, Todd M; Stuart, Gregory L

2017-03-01

Research demonstrates alcohol temporally precedes and increases the odds of violence between intimate partners. However, despite an extensive theoretical literature on factors that likely moderate the relationship between alcohol and dating violence, minimal empirical research has examined such moderators. The purpose of the present study was to examine two potential moderators of this association: trait anger and partner-specific anger management. Undergraduate men (N = 67) who had consumed alcohol within the past month and were in current dating relationships completed a baseline assessment of their trait anger and partner-specific anger management skills and subsequently completed daily assessments of their alcohol use and violence perpetration (psychological, physical, and sexual) for up to 90 consecutive days. Alcohol was significantly associated with increased odds of physical aggression among men with relatively high but not low trait anger and partner-specific anger management deficits. In contrast, alcohol was significantly associated with increased odds of sexual aggression among men with relatively low trait anger and partner-specific anger management deficits. Our findings demonstrate important differences in the roles of acute intoxication and anger management in the risk of physical aggression and sexual dating violence. Interventions for dating violence may benefit from targeting both alcohol and adaptive anger management skills.

Jealousy during Dating among Female College Students

ERIC Educational Resources Information Center

Khanchandani, Laveena; Durham, Thomas W.

2009-01-01

This study examined the relationship between several situational and personality variables and jealousy in dating relationships among 100 college women volunteers who completed a series of questionnaires about themselves and their dating situations. Six research questions were examined. Results showed that jealousy was lower for women in a steady…

24 CFR 3282.412 - Completion of remedial actions and report.

Code of Federal Regulations, 2010 CFR

2010-04-01

... files for five years from the date the notification campaign is completed a copy of the notice sent and a complete list of the people and their addresses. The files referred to in this section shall be... maintain in its files, for five years from the date the correction campaign is completed, one of the...

40 CFR 75.4 - Compliance dates.

Code of Federal Regulations, 2014 CFR

2014-07-01

... relative accuracy test audit (RATA) of the high measurement scale of the monitor is successfully completed... tests required under § 75.20(c) and section 6 of appendix A to this part for the high measurement scale... that all certification tests are completed no later than the following dates (except as provided in...

40 CFR 75.4 - Compliance dates.

Code of Federal Regulations, 2012 CFR

2012-07-01

... relative accuracy test audit (RATA) of the high measurement scale of the monitor is successfully completed... tests required under § 75.20(c) and section 6 of appendix A to this part for the high measurement scale... that all certification tests are completed no later than the following dates (except as provided in...

40 CFR 75.4 - Compliance dates.

Code of Federal Regulations, 2013 CFR

2013-07-01

... relative accuracy test audit (RATA) of the high measurement scale of the monitor is successfully completed... tests required under § 75.20(c) and section 6 of appendix A to this part for the high measurement scale... that all certification tests are completed no later than the following dates (except as provided in...

Drinking and Dating: Examining the Link among Relationship Satisfaction, Hazardous Drinking, and Readiness-to-Change in College Dating Relationships

ERIC Educational Resources Information Center

Khaddouma, Alexander; Shorey, Ryan C.; Brasfield, Hope; Febres, Jeniimarie; Zapor, Heather; Elmquist, Joanna; Stuart, Gregory L.

2016-01-01

For this study we examined the association between relationship satisfaction and readiness-to-change alcohol use, as well as the associations between hazardous drinking and readiness-to-change relationship issues in college dating relationships. A sample of 219 college students in a current dating relationship (aged 18-25) completed self-report…

Primate phylogenetic relationships and divergence dates inferred from complete mitochondrial genomes.

PubMed

Pozzi, Luca; Hodgson, Jason A; Burrell, Andrew S; Sterner, Kirstin N; Raaum, Ryan L; Disotell, Todd R

2014-06-01

The origins and the divergence times of the most basal lineages within primates have been difficult to resolve mainly due to the incomplete sampling of early fossil taxa. The main source of contention is related to the discordance between molecular and fossil estimates: while there are no crown primate fossils older than 56Ma, most molecule-based estimates extend the origins of crown primates into the Cretaceous. Here we present a comprehensive mitogenomic study of primates. We assembled 87 mammalian mitochondrial genomes, including 62 primate species representing all the families of the order. We newly sequenced eleven mitochondrial genomes, including eight Old World monkeys and three strepsirrhines. Phylogenetic analyses support a strong topology, confirming the monophyly for all the major primate clades. In contrast to previous mitogenomic studies, the positions of tarsiers and colugos relative to strepsirrhines and anthropoids are well resolved. In order to improve our understanding of how fossil calibrations affect age estimates within primates, we explore the effect of seventeen fossil calibrations across primates and other mammalian groups and we select a subset of calibrations to date our mitogenomic tree. The divergence date estimates of the Strepsirrhine/Haplorhine split support an origin of crown primates in the Late Cretaceous, at around 74Ma. This result supports a short-fuse model of primate origins, whereby relatively little time passed between the origin of the order and the diversification of its major clades. It also suggests that the early primate fossil record is likely poorly sampled. Copyright © 2014 Elsevier Inc. All rights reserved.

The Influence of Dating Anxiety on Normative Experiences of Dating, Sexual Interactions, and Alcohol Consumption among Canadian Middle Adolescents

ERIC Educational Resources Information Center

Boyle, Andrea M.; O'Sullivan, Lucia F.

2013-01-01

Adolescents tend to consume alcohol and find romantic and sexual partners in mixed-group settings that are unmonitored by adults. Relatively little is known about the influence that dating anxiety may have with these social interactions. A sample of 163 high school students (aged 14-17 years) completed online surveys assessing dating, sex, and…

Research notes : ensuring project performance and adherence to completion dates.

DOT National Transportation Integrated Search

2009-04-01

A recently completed ODOT research project, led by David Sillars at Oregon State University, sought to identify alternative methods to liquidated damages for ODOT to encourage on-time project delivery and to develop a model to aid in selecting among ...

Assessing Date Palm Genetic Diversity Using Different Molecular Markers.

PubMed

Atia, Mohamed A M; Sakr, Mahmoud M; Adawy, Sami S

2017-01-01

Molecular marker technologies which rely on DNA analysis provide powerful tools to assess biodiversity at different levels, i.e., among and within species. A range of different molecular marker techniques have been developed and extensively applied for detecting variability in date palm at the DNA level. Recently, the employment of gene-targeting molecular marker approaches to study biodiversity and genetic variations in many plant species has increased the attention of researchers interested in date palm to carry out phylogenetic studies using these novel marker systems. Molecular markers are good indicators of genetic distances among accessions, because DNA-based markers are neutral in the face of selection. Here we describe the employment of multidisciplinary molecular marker approaches: amplified fragment length polymorphism (AFLP), start codon targeted (SCoT) polymorphism, conserved DNA-derived polymorphism (CDDP), intron-targeted amplified polymorphism (ITAP), simple sequence repeats (SSR), and random amplified polymorphic DNA (RAPD) to assess genetic diversity in date palm.

Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1.

PubMed

Zandarashvili, Levani; White, Mark A; Esadze, Alexandre; Iwahara, Junji

2015-07-08

The inducible transcription factor Egr-1 binds specifically to 9-bp target sequences containing two CpG sites that can potentially be methylated at four cytosine bases. Although it appears that complete CpG methylation would make an unfavorable steric clash in the previous crystal structures of the complexes with unmethylated or partially methylated DNA, our affinity data suggest that DNA recognition by Egr-1 is insensitive to CpG methylation. We have determined, at a 1.4-Å resolution, the crystal structure of the Egr-1 zinc-finger complex with completely methylated target DNA. Structural comparison of the three different methylation states reveals why Egr-1 can recognize the target sequences regardless of CpG methylation. Copyright © 2015 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

Complete to Compete: Common College Completion Metrics. Technical Guide

ERIC Educational Resources Information Center

Reyna, Ryan; Reindl, Travis; Witham, Keith; Stanley, Jeff

2010-01-01

Improved college completion rates are critical to the future of the United States, and states must have better data to understand the nature of the challenges they confront or target areas for policy change. The 2010-2011 National Governors Association (NGA) Chair's initiative, "Complete to Compete", recommends that all states collect data from…

Perceptions of adolescents, parents, and school personnel from a predominantly Cuban American community regarding dating and teen dating violence prevention.

PubMed

Gonzalez-Guarda, Rosa M; Cummings, Amanda M; Pino, Karen; Malhotra, Krithika; Becerra, Maria M; Lopez, Jessica E

2014-04-01

The purpose of this study was to explore perceptions of dating relationships and teen dating violence prevention within a predominantly Cuban American community in Miami-Dade County. Eight focus groups (n = 74 participants) with adolescents of Hispanic origin (n = 29), their parents (n = 29), and school personnel (n = 16) were conducted and analyzed using content analysis. Four themes characterized the nature and context of dating relationships among adolescents of Hispanic origin: YOLO -You Only Live Once, cultural unity but social division, dating is not going out, and the social environment challenges healthy relationships. The information generated from this study can be used to develop culturally tailored teen dating violence prevention programs targeting youth of Hispanic origin. © 2014 Wiley Periodicals, Inc.

An Evaluation of a Mixed-Gender Date Rape Prevention Workshop.

ERIC Educational Resources Information Center

Holcomb, Derek R.; And Others

1993-01-01

Compared date rape attitudes in college students who did and did not complete a mixed-gender date rape workshop. Survey results indicated men were more tolerant of date rape than women; control group students were more tolerant than treatment group students; and men exhibited a greater program effect than women. (SM)

Social Information Processing in Dating Conflicts: Reciprocal Relationships With Dating Aggression in a One-Year Prospective Study.

PubMed

Calvete, Esther; Orue, Izaskun; Gamez-Guadix, Manuel; López de Arroyabe, Elena

2016-04-01

The aim of this study was to assess the reciprocal associations among social information processing (SIP) in dating conflicts and the perpetration of dating aggression. A first step involved the development of a measure (The Social Information Processing Questionnaire in Dating Conflicts, SIPQ-DC) to assess social information in scenarios of conflict with dating partners. A sample of 1,272 adolescents (653 girls, 619 boys; Mage = 14.74 years, SD = 1.21) completed measures of SIP and dating aggression perpetration in two different times, which were spaced 1 year apart. Confirmatory factor analyses provided support for a model with five correlated factors for the SIPQ-DC, namely, hostile attribution, anger, aggressive response access, anticipation of positive consequences for oneself, and anticipation of negative consequences for partners. Although the perpetration of dating aggression at T1 was cross-sectionally associated with all the SIP components, anger was the only component that predicted the residual increase in dating aggression behavior over time. The perpetration of dating aggression predicted a worsening of cognitive-emotional processes involved in dating conflicts. Some longitudinal paths were significant only in male adolescents. In conclusion, relationships among SIP and aggression are reciprocal. Gender differences in longitudinal paths can contribute to explaining men's higher perpetration of violence in adulthood. © The Author(s) 2014.

FNAS CRRES program completion

NASA Technical Reports Server (NTRS)

Miller, George P.

1992-01-01

An agenda and the list of attendees at the Combined Release and Radiation Effects Satellite (CRRES) IWG meeting, held on 14-15 Dec. 1992, are presented. Short summaries of the work that has been completed to date, in support of the contract, are presented.

Adolescent Dating Experiences Described by Latino College Students

ERIC Educational Resources Information Center

Raffaelli, M.

2005-01-01

Latino college students (M age=21.4 years) completed self-report surveys assessing adolescent dating experiences. Compared to young men (n=69), young women (n=97) had more limitations placed on them by parents as adolescents and began dating later. No gender difference in timing of the first serious relationship emerged. More young women had their…

Targeting Ovarian Cancer with Porphysome Nanotechnology

DTIC Science & Technology

2016-10-01

ORGANIZATION: University Health Network Toronto, ON, Canada M5G 2C4 REPORT DATE : October 2016 TYPE OF REPORT: Annual PREPARED FOR: U.S. Army...THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) October 2016 2. REPORT TYPE Annual 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE Targeting...non-targeted Porphysomes for the detection of orthotopic ovarian lesions. Methods : Two ovarian tumour xenograft models are established with human SK

Wasted research when systematic reviews fail to provide a complete and up-to-date evidence synthesis: the example of lung cancer.

PubMed

Créquit, Perrine; Trinquart, Ludovic; Yavchitz, Amélie; Ravaud, Philippe

2016-01-20

Multiple treatments are frequently available for a given condition, and clinicians and patients need a comprehensive, up-to-date synthesis of evidence for all competing treatments. We aimed to quantify the waste of research related to the failure of systematic reviews to provide a complete and up-to-date evidence synthesis over time. We performed a series of systematic overviews and networks of randomized trials assessing the gap between evidence covered by systematic reviews and available trials of second-line treatments for advanced non-small cell lung cancer. We searched the Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects, MEDLINE, EMBASE, and other resources sequentially by year from 2009 to March 2, 2015. We sequentially compared the amount of evidence missing from systematic reviews to the randomized evidence available for inclusion each year. We constructed cumulative networks of randomized evidence over time and evaluated the proportion of trials, patients, treatments, and treatment comparisons not covered by systematic reviews on December 31 each year from 2009 to 2015. We identified 77 trials (28,636 patients) assessing 47 treatments with 54 comparisons and 29 systematic reviews (13 published after 2013). From 2009 to 2015, the evidence covered by existing systematic reviews was consistently incomplete: 45 % to 70 % of trials; 30 % to 58 % of patients; 40 % to 66 % of treatments; and 38 % to 71 % of comparisons were missing. In the cumulative networks of randomized evidence, 10 % to 17 % of treatment comparisons were partially covered by systematic reviews and 55 % to 85 % were partially or not covered. We illustrate how systematic reviews of a given condition provide a fragmented, out-of-date panorama of the evidence for all treatments. This waste of research might be reduced by the development of live cumulative network meta-analyses.

Overview of Progress on the LANSCE Accelerator and Target Facilities Improvement Program

NASA Astrophysics Data System (ADS)

Macek, R. J.; Brun, T.; Donahue, J. B.; Fitzgerald, D. H.

1997-05-01

Three projects to improve the performance of the accelerator and target facilities for the Los Alamos Neutron Science Center have been initiated since 1994. The LANSCE Reliability Improvement Project was separated into two phases. Phase I, completed in 1995, was targeted at near-term improvements to beam availability that could be completed in a year. Phase II, now underway, consists of two projects: 1) converting the beam injection into the Proton Storage Ring (PSR) from the present two-step process H^- to H^0 to H^+) to direct injection of H^- beam in one step (H^- to H^+), and 2) an upgrade of the spallation neutron production target which will reduce the target change-out time from about a year to about three weeks. The third project, the SPSS Enhancement Project, is aimed at increasing the PSR output beam current from the present 70 μA at 20 Hz to 200 μA at 30 Hz, plus implementing seven new neutron scattering instruments. Objectives, plans, results and progress to date will be summarized.

A feasibility study to assess the effectiveness of safe dates for teen mothers.

PubMed

Herrman, Judith W; Waterhouse, Julie K

2014-01-01

To determine the effectiveness of the adapted Safe Dates curriculum as an intervention for pregnant and/or parenting teens to prevent teen dating violence (TDV). This pre-/posttest, single-sample study provided a means to assess the effectiveness of an adapted Safe Dates curriculum for teen mothers. The adapted Safe Dates curriculum was implemented in three schools designed for the unique needs of teens who are pregnant and/or parenting. The final sample of 41 teen participants, with a mean age of 16.27, completed 80% of the curriculum and two of the three assessments. Most of the teens were pregnant during participation in the curriculum, and six had infants between age 1 and 3 months. The teen mothers completed the pretest, participated in the 10-session adapted Safe Dates curriculum, and completed the posttest at the end of the program and 1 month after program completion. The pre/posttest was adapted from the Safe Dates curriculum-specific evaluation instrument. Senior, undergraduate nursing students were trained in and implemented the curriculum. Participation in the adapted Safe Dates program yielded significant differences in the areas of responses to anger, gender stereotyping, awareness of resources for perpetrators and victims, and psychological violence perpetration. This adapted program may be effective in changing selected outcomes. The implementation of a larger scale, experimental/control group study may demonstrate the program's efficacy at reducing the incidence of TDV among teen mothers. © 2014 AWHONN, the Association of Women's Health, Obstetric and Neonatal Nurses.

Theranostics Targeting Metastatic Breast Cancer

DTIC Science & Technology

2017-10-01

AWARD NUMBER: W81XWH-15-1-0389 TITLE: Theranostics Targeting Metastatic Breast Cancer PRINCIPAL INVESTIGATOR: Kevin Burgess CONTRACTING...ADDRESS. 1. REPORT DATE October 2017 2. REPORT TYPE Annual 3. DATES COVERED 4. TITLE AND SUBTITLE Theranostics Targeting Metastatic Breast Cancer 5a...safe and effective interventions; (ii) elimination of mortality associated with metastatic breast cancer ; and, (iii) distinguishing aggressive breast

The effects of moms and teens for safe dates: a dating abuse prevention program for adolescents exposed to domestic violence.

PubMed

Foshee, Vangie A; Benefield, Thad; Dixon, Kimberly S; Chang, Ling-Yin; Senkomago, Virginia; Ennett, Susan T; Moracco, Kathryn E; Michael Bowling, J

2015-05-01

Adolescents exposed to domestic violence are at high risk for dating abuse. This randomized controlled trial evaluated a dating abuse prevention program designed specifically for this risk group. Moms and Teens for Safe Dates consisted of six mailed booklets of dating abuse prevention information and interactive activities. Mothers who had been victims of domestic violence but no longer lived with the abuser delivered the program to their adolescents who had been exposed to the abuse. Mother and adolescent pairs (N = 409) were recruited through community advertising; the adolescents ranged from 12 to 16 years old and 64 % were female. Mothers and adolescents completed baseline and 6-month follow-up telephone interviews. Booklet completion in the treatment group ranged from 80 % for the first to 62 % for the last booklet. The analyses first tested whether program effects on dating abuse varied by four a priori identified moderators (mother's psychological health, the amount of adolescent exposure to domestic violence, and adolescent sex and race/ethnicity). Main effects of the program were examined when there were no differential program effects. Program effects on psychological and physical victimization and psychological and cyber perpetration were moderated by the amount of adolescent exposure to domestic violence; there were significant favorable program effects for adolescents with higher, but not lower levels of exposure to domestic violence. There were no moderated or main effects on sexual violence victimization and perpetration or cyber victimization. The findings suggest that a dating abuse prevention program designed for adolescents exposed to domestic violence can have important positive effects.

Safe Sex Messages Within Dating and Entertainment Smartphone Apps: A Review.

PubMed

Huang, Evelyn Tzu-Yen; Williams, Henrietta; Hocking, Jane S; Lim, Megan Sc

2016-11-08

Smartphone apps provide a new platform for entertainment, information distribution, and health promotion activities, as well as for dating and casual sexual encounters. Previous research has shown high acceptability of sexual health interventions via smartphone apps; however, sexual health promotion apps were infrequently downloaded and underused. Integrating sexual health promotion into established apps might be a more effective method. The objective of our study was to critically review popular sex-related apps and dating apps, in order to ascertain whether they contain any sexual health content. Part 1: In January 2015, we used the term "sexual" to search for free apps in the Apple iTunes store and Android Google Play store, and categorized the sexual health content of the 137 apps identified. Part 2: We used the term "dating" to search for free geosocial-networking apps in the Apple iTunes and Android Google Play stores. The apps were downloaded to test functionality and to determine whether they included sexual health content. Part 1: Of the 137 apps identified, 15 (11.0%) had sexual health content and 15 (11.0%) contained messages about sexual assault or violence. The majority of the apps did not contain any sexual health content. Part 2: We reviewed 60 dating apps: 44 (73%) targeting heterosexual users, 9 (15%) targeting men who have sex with men (MSM), 3 (5%) targeting lesbian women, and 4 (7%) for group dating. Only 9 dating apps contained sexual health content, of which 7 targeted MSM. The majority of sex-related apps and dating apps contained no sexual health content that could educate users about and remind them of their sexual risks. Sexual health practitioners and public health departments will need to work with app developers to promote sexual health within existing popular apps. For those apps that already contain sexual health messages, further study to investigate the effectiveness of the content is needed. ©Evelyn Tzu-Yen Huang, Henrietta

Intern Programs | Key Dates

Science.gov Websites

Application Deadline Program Dates CCI October 16, 2017 January 12, 2018 June 4–August 10, 2018 GEM –August 31, 2018 Lee Teng November 2017 January 22, 2018 May 29–August 10, 2018 QuarkNet March 19, 2018 –August 10, 2018 SULI October 16, 2017 January 12, 2018 June 4–August 10, 2018 TARGET December 18, 2017

Dating Violence and Girls in the Juvenile Justice System

ERIC Educational Resources Information Center

Kelly, Patricia J.; Cheng, An-Lin; Peralez-Dieckmann, Esther; Martinez, Elisabeth

2009-01-01

The purpose of this study is to explore the prevalence and associated behaviors of dating violence among a population of girls in the juvenile justice system. A sample of 590 girls from an urban juvenile justice system completed a questionnaire assessing attitudes and self-efficacy about and occurrence of dating violence. The analysis developed a…

Dating violence and girls in the juvenile justice system.

PubMed

Kelly, Patricia J; Cheng, An-Lin; Peralez-Dieckmann, Esther; Martinez, Elisabeth

2009-09-01

The purpose of this study is to explore the prevalence and associated behaviors of dating violence among a population of girls in the juvenile justice system. A sample of 590 girls from an urban juvenile justice system completed a questionnaire assessing attitudes and self-efficacy about and occurrence of dating violence. The analysis developed a random effect model to determine a risk profile for dating violence. The strongest predictors of dating violence were (a) initial sexual experience at age 13 or earlier, (b) unwillingness of initial sexual experience, (c) drug use, and (d) low self-efficacy about preventing dating violence. The high prevalence of dating violence and associated behaviors among participants suggests the importance of implementing primary prevention programs to assist preteen girls in delaying initial sexual intercourse and in learning techniques to prevent dating violence.

24 CFR 954.507 - Submission of project completion reports.

Code of Federal Regulations, 2010 CFR

2010-04-01

... request for the project. If a satisfactory Project Completion Report is not submitted by the due date, HUD... approvals will remain suspended until a satisfactory Project Completion Report is received. (Approved by the...

Capturing the benefits of complete streets.

DOT National Transportation Integrated Search

2015-12-01

Anecdotal information indicates that private investment and property value increases are associated : with featured Complete Streets projects. However, to date, little research has been done to confirm : these benefits. Much of the relevant literatur...

The Effects of the Moms and Teens for Safe Dates Program on Dating Abuse: a Conditional Process Analysis.

PubMed

Foshee, Vangie A; Benefield, Thad; Chen, May S; Reyes, Luz McNaughton; Dixon, Kimberly S; Ennett, Susan T; Moracco, Kathryn E; Bowling, J Michael

2016-04-01

Moms and Teens for Safe Dates (MTSD) is a dating abuse (DA) prevention program for teens exposed to domestic violence. In a randomized controlled trial (RCT), MTSD prevented certain types of DA victimization (psychological and physical) and perpetration (psychological and cyber) among teens with higher, but not lower, exposure to domestic violence. We built on these findings by using moderated mediation analysis to examine whether level of teen exposure to domestic violence conditioned the indirect effects of MTSD on these types of DA through targeted mediators. MTSD consisted of six mailed activity booklets. Mothers who had been former victims of domestic violence delivered the program to their teens. Mother and teen pairs were recruited into the RCT through community advertising and completed baseline and 6-month follow-up interviews (N = 277 pairs). As expected, MTSD had significant favorable effects for teens with higher but not lower exposure to domestic violence on several mediators that guided program content, including teen conflict management skills and mother-perceived severity of DA, self-efficacy for enacting DA prevention efforts, and comfort in communicating with her teen. MTSD had significant main effects on other mediators including teen feeling of family closeness and cohesion and mother-perceived susceptibility of her teen to DA. As expected, all significant indirect effects of MTSD on DA outcomes through mediators were for teens with higher exposure to domestic violence. Findings have implications for developing DA victimization and perpetration prevention programs for teens with high exposure to domestic violence.

Multi-targeted priming for genome-wide gene expression assays.

PubMed

Adomas, Aleksandra B; Lopez-Giraldez, Francesc; Clark, Travis A; Wang, Zheng; Townsend, Jeffrey P

2010-08-17

Complementary approaches to assaying global gene expression are needed to assess gene expression in regions that are poorly assayed by current methodologies. A key component of nearly all gene expression assays is the reverse transcription of transcribed sequences that has traditionally been performed by priming the poly-A tails on many of the transcribed genes in eukaryotes with oligo-dT, or by priming RNA indiscriminately with random hexamers. We designed an algorithm to find common sequence motifs that were present within most protein-coding genes of Saccharomyces cerevisiae and of Neurospora crassa, but that were not present within their ribosomal RNA or transfer RNA genes. We then experimentally tested whether degenerately priming these motifs with multi-targeted primers improved the accuracy and completeness of transcriptomic assays. We discovered two multi-targeted primers that would prime a preponderance of genes in the genomes of Saccharomyces cerevisiae and Neurospora crassa while avoiding priming ribosomal RNA or transfer RNA. Examining the response of Saccharomyces cerevisiae to nitrogen deficiency and profiling Neurospora crassa early sexual development, we demonstrated that using multi-targeted primers in reverse transcription led to superior performance of microarray profiling and next-generation RNA tag sequencing. Priming with multi-targeted primers in addition to oligo-dT resulted in higher sensitivity, a larger number of well-measured genes and greater power to detect differences in gene expression. Our results provide the most complete and detailed expression profiles of the yeast nitrogen starvation response and N. crassa early sexual development to date. Furthermore, our multi-targeting priming methodology for genome-wide gene expression assays provides selective targeting of multiple sequences and counter-selection against undesirable sequences, facilitating a more complete and precise assay of the transcribed sequences within the genome.

Substance Use and Physical Dating Violence

PubMed Central

Reyes, H. Luz McNaughton; Foshee, Vangie A.; Tharp, Andra T.; Ennett, Susan T.; Bauer, Daniel J.

2015-01-01

Introduction Theoretic models suggest that associations between substance use and dating violence perpetration may vary in different social contexts, but few studies have examined this proposition. The current study examined whether social control and violence in the neighborhood, peer, and family contexts moderate the associations between substance use (heavy alcohol use, marijuana, and hard drug use) and adolescent physical dating violence perpetration. Methods Adolescents in the eighth, ninth, and tenth grades completed questionnaires in 2004 and again four more times until 2007 when they were in the tenth, 11th and 12th grades. Multilevel analysis was used to examine interactions between each substance and measures of neighborhood, peer, and family social control and violence as within-person (time-varying) predictors of physical dating violence perpetration across eighth through 12th grade (N=2,455). Analyses were conducted in 2014. Results Physical dating violence perpetration increased at time points when heavy alcohol and hard drug use were elevated; these associations were weaker when neighborhood social control was higher and stronger when family violence was higher. Also, the association between heavy alcohol use and physical dating violence perpetration was weaker when teens had more-prosocial peer networks and stronger when teens’ peers reported more physical dating violence. Conclusions Linkages between substance use and physical dating violence perpetration depend on substance use type and levels of contextual violence and social control. Prevention programs that address substance use–related dating violence should consider the role of social contextual variables that may condition risk by influencing adolescents’ aggression propensity. PMID:26296445

Safe Sex Messages Within Dating and Entertainment Smartphone Apps: A Review

PubMed Central

Williams, Henrietta; Hocking, Jane S; Lim, Megan SC

2016-01-01

Background Smartphone apps provide a new platform for entertainment, information distribution, and health promotion activities, as well as for dating and casual sexual encounters. Previous research has shown high acceptability of sexual health interventions via smartphone apps; however, sexual health promotion apps were infrequently downloaded and underused. Integrating sexual health promotion into established apps might be a more effective method. Objective The objective of our study was to critically review popular sex-related apps and dating apps, in order to ascertain whether they contain any sexual health content. Methods Part 1: In January 2015, we used the term “sexual” to search for free apps in the Apple iTunes store and Android Google Play store, and categorized the sexual health content of the 137 apps identified. Part 2: We used the term “dating” to search for free geosocial-networking apps in the Apple iTunes and Android Google Play stores. The apps were downloaded to test functionality and to determine whether they included sexual health content. Results Part 1: Of the 137 apps identified, 15 (11.0%) had sexual health content and 15 (11.0%) contained messages about sexual assault or violence. The majority of the apps did not contain any sexual health content. Part 2: We reviewed 60 dating apps: 44 (73%) targeting heterosexual users, 9 (15%) targeting men who have sex with men (MSM), 3 (5%) targeting lesbian women, and 4 (7%) for group dating. Only 9 dating apps contained sexual health content, of which 7 targeted MSM. Conclusions The majority of sex-related apps and dating apps contained no sexual health content that could educate users about and remind them of their sexual risks. Sexual health practitioners and public health departments will need to work with app developers to promote sexual health within existing popular apps. For those apps that already contain sexual health messages, further study to investigate the effectiveness of the

40 CFR 75.4 - Compliance dates.

Code of Federal Regulations, 2011 CFR

2011-07-01

....e., SO2 or NOX, as applicable): (A) Only if the relative accuracy test audit (RATA) of the high... that all certification tests are completed no later than the following dates (except as provided in... an oil-fired Phase II unit, January 1, 1995, except that installation and certification tests for...

Effect of date seeds on oxidative damage and antioxidant status in vivo.

PubMed

Habib, Hosam M; Ibrahim, Wissam H

2011-07-01

Date seeds have been shown to contain high amounts of antioxidants. However, in vivo studies on date seeds are lacking. Therefore the purpose of this study was to determine the effect of date seeds on oxidative damage and antioxidant status in vivo. Male Wistar rats were fed a basal diet containing 0, 70 or 140 g kg(-1) date seeds for 30 days. All three diets were isonitrogenous and isocaloric. Indication of oxidative damage was assessed in the liver and serum, and antioxidant status was assessed in the liver. Serum biochemical parameters, including indicators of tissue cellular damage and complete blood count with differential, were also determined. The results showed that date seeds significantly (P<0.05) reduced liver and serum malondialdehyde (a lipid peroxidative damage product) and serum lactate dehydrogenase and creatine kinase. Liver antioxidants (vitamin E, vitamin C, glutathione, superoxide dismutase, glutathione peroxidase and catalase), complete blood count with differential and other serum biochemical parameters assessed were not significantly altered by date seeds. The results obtained suggest a protective effect of date seeds against in vivo oxidative damage, possibly through the action of their bioactive antioxidants. Copyright © 2011 Society of Chemical Industry.

Psychiatric and Cognitive Functioning in Adolescent Inpatients with Histories of Dating Violence Victimization

PubMed Central

Rizzo, Christie J.; Esposito-Smythers, Christianne; Spirito, Anthony; Thompson, Ariel

2010-01-01

The presence of dating violence victimization as well as its relation to psychiatric diagnosis and cognitive processes was examined in a sample of 155 adolescents hospitalized in a psychiatric facility. Participants and their parents completed semi-structured diagnostic interviews. Participants also completed self-report measures of dating violence victimization and cognitive functioning. Seventy-seven percent of adolescents who had initiated dating reported psychological, physical, and/or sexual abuse by a dating partner over the past year. Victims of psychological abuse alone as well as physical and/or sexual violence endorsed higher rates of major depressive disorder compared to non-victims. Physical/sexual dating violence victims also endorsed significantly higher rates of PTSD and alcohol use disorders, more frequent co-occurrence of externalizing and internalizing disorders, and more frequent negative cognitive biases, relative to non-victimized adolescents. Findings suggest that psychiatrically hospitalized adolescents with dating violence histories represent a subgroup of adolescent inpatients with a particularly serious clinical picture. PMID:20824193

Developmental Associations Between Adolescent Alcohol Use and Dating Aggression

PubMed Central

Reyes, H. Luz McNaughton; Foshee, Vangie A.; Bauer, Daniel J.; Ennett, Susan T.

2012-01-01

While numerous studies have established a link between alcohol use and partner violence in adulthood, little research has examined this relation during adolescence. The current study used multivariate growth models to examine relations between alcohol use and dating aggression across grades 8 through 12 controlling for shared risk factors (common causes) that predict both behaviors. Associations between trajectories of alcohol use and dating aggression were reduced substantially when common causes were controlled. Concurrent associations between the two behaviors were significant across nearly all grades but no evidence was found for prospective connections from prior alcohol use to subsequent dating aggression or vice versa. Findings suggest that prevention efforts should target common causes of alcohol use and dating aggression. PMID:23589667

Measuring homework completion in behavioral activation.

PubMed

Busch, Andrew M; Uebelacker, Lisa A; Kalibatseva, Zornitsa; Miller, Ivan W

2010-07-01

The aim of this study was to develop and validate an observer-based coding system for the characterization and completion of homework assignments during Behavioral Activation (BA). Existing measures of homework completion are generally unsophisticated, and there is no current measure of homework completion designed to capture the particularities of BA. The tested scale sought to capture the type of assignment, realm of functioning targeted, extent of completion, and assignment difficulty. Homework assignments were drawn from 12 (mean age = 48, 83% female) clients in two trials of a 10-session BA manual targeting treatment-resistant depression in primary care. The two coders demonstrated acceptable or better reliability on most codes, and unreliable codes were dropped from the proposed scale. In addition, correlations between homework completion and outcome were strong, providing some support for construct validity. Ultimately, this line of research aims to develop a user-friendly, reliable measure of BA homework completion that can be completed by a therapist during session.

Direct memory access transfer completion notification

DOEpatents

Archer, Charles J [Rochester, MN; Blocksome, Michael A [Rochester, MN; Parker, Jeffrey J [Rochester, MN

2011-02-15

DMA transfer completion notification includes: inserting, by an origin DMA engine on an origin node in an injection first-in-first-out (`FIFO`) buffer, a data descriptor for an application message to be transferred to a target node on behalf of an application on the origin node; inserting, by the origin DMA engine, a completion notification descriptor in the injection FIFO buffer after the data descriptor for the message, the completion notification descriptor specifying a packet header for a completion notification packet; transferring, by the origin DMA engine to the target node, the message in dependence upon the data descriptor; sending, by the origin DMA engine, the completion notification packet to a local reception FIFO buffer using a local memory FIFO transfer operation; and notifying, by the origin DMA engine, the application that transfer of the message is complete in response to receiving the completion notification packet in the local reception FIFO buffer.

Consequences of Dating for Post-Divorce Maternal Well-Being

PubMed Central

Langlais, Michael R.; Anderson, Edward R.; Greene, Shannon M.

2016-01-01

Repartnering has been linked to health benefits for mothers, yet few studies have examined relationship quality in this context. According to the divorce-stress-adaptation perspective, relationship quality may influence the relationship between maternal well-being and dating after divorce. The current study examines the consequences of dating, relationship quality, and dating transitions (breaking up and dating new partners) on maternal well-being (negative affect and life satisfaction). Using monthly surveys completed by mothers over a two-year period after filing for divorce, we examined changes in intercepts and slopes of dating status and transitions for maternal well-being while also testing the effects of relationship quality. Mothers entering high-quality relationships were likely to report boosts in well-being at relationship initiation compared to single mothers and mothers entering low-quality relationships. Mothers entering lower-quality relationships were likely to report lower levels of well-being than single mothers. Dating transitions were associated with increases in well-being. Implications for maternal adjustment are discussed. PMID:27746511

Present and future of metastatic colorectal cancer treatment: A review of new candidate targets

PubMed Central

Martini, Giulia; Troiani, Teresa; Cardone, Claudia; Vitiello, Pietropaolo; Sforza, Vincenzo; Ciardiello, Davide; Napolitano, Stefania; Della Corte, Carminia Maria; Morgillo, Floriana; Raucci, Antonio; Cuomo, Antonio; Selvaggi, Francesco; Ciardiello, Fortunato; Martinelli, Erika

2017-01-01

In the last two decades, great efforts have been made in the treatment of metastatic colorectal cancer (mCRC) due to the approval of new target agents for cytotoxic drugs. Unfortunately, a large percentage of patients present with metastasis at the time of diagnosis or relapse after a few months. The complex molecular heterogeneity of this disease is not completely understood; to date, there is a lack of predictive biomarkers that can be used to select subsets of patients who may respond to target drugs. Only the RAS-mutation status is used to predict resistance to anti-epidermal growth factor receptor agents in patients with mCRC. In this review, we describe approved targeted therapies for the management of metastatic mCRC and discuss new candidate targets on the horizon. PMID:28765689

Direct memory access transfer completion notification

DOEpatents

Archer, Charles J.; Blocksome, Michael A.; Parker, Jeffrey J.

2010-08-17

Methods, apparatus, and products are disclosed for DMA transfer completion notification that include: inserting, by an origin DMA engine on an origin compute node in an injection FIFO buffer, a data descriptor for an application message to be transferred to a target compute node on behalf of an application on the origin compute node; inserting, by the origin DMA engine, a completion notification descriptor in the injection FIFO buffer after the data descriptor for the message, the completion notification descriptor specifying an address of a completion notification field in application storage for the application; transferring, by the origin DMA engine to the target compute node, the message in dependence upon the data descriptor; and notifying, by the origin DMA engine, the application that the transfer of the message is complete, including performing a local direct put operation to store predesignated notification data at the address of the completion notification field.

Targeting ESR1-Mutant Breast Cancer

DTIC Science & Technology

2015-09-01

Award Number: W81XWH-14-1-0360 TITLE: Targeting ESR1 -Mutant Breast Cancer PRINCIPAL INVESTIGATOR: Geoffrey L. Greene, Ph.D. CONTRACTING...ADDRESS. 1. REPORT DATE September 2015 2. REPORT TYPE Annual 3. DATES COVERED 1 Sep 2014 - 31 Aug 2015 4. TITLE AND SUBTITLE Targeting ESR1 -Mutant...Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT The hypothesis of this proposal is that LBD mutations in ESR1 promote resistance to current FDA

Depressive Symptoms Moderate Dating Violence Prevention Outcomes Among Adolescent Girls.

PubMed

Collibee, Charlene; Rizzo, Christie J; Kemp, Kathleen; Hood, Erik; Doucette, Hannah; Gittins Stone, Daniel I; DeJesus, Brett

2018-04-01

Few dating violence prevention programs assess how variations in initial violence risk affects responsiveness. This study examines the efficacy of Date SMART, a dating violence and sexual risk prevention program designed to target high-risk adolescent girls, in preventing dating violence in the context of varying initial levels of depressive symptoms. A diverse sample of N = 109 female adolescents with a history of physical dating violence participated in a randomized controlled trial of the Date SMART program and a knowledge only (KO) comparison. Using baseline depression level as a primary risk factor, a series of multilevel models revealed significant main effects of baseline depression such that higher baseline depression was associated with greater physical dating violence perpetration and victimization. Results also showed a three-way interaction for assessment point, depressive symptoms, and condition for physical dating violence perpetration. Specifically, those with higher baseline depression in Date SMART showed significantly less physical dating violence perpetration at follow-ups compared with those with higher baseline depression in the KO group. This difference in violence reduction between conditions was not observed for those with lower baseline depression. Date SMART appears to effectively reduce physical dating violence perpetration in those with higher levels of initial risk. Current findings support that adolescents with different risk profiles respond differently to violence prevention programs.

The Impacts of Using Smartphone Dating Applications on Sexual Risk Behaviours in College Students in Hong Kong.

PubMed

Choi, Edmond Pui-Hang; Wong, Janet Yuen-Ha; Lo, Herman Hay-Ming; Wong, Wendy; Chio, Jasmine Hin-Man; Fong, Daniel Yee-Tak

2016-01-01

Dating applications (apps) on smartphones have become increasingly popular. The aim of this study was to explore the association between the use of dating apps and risky sexual behaviours. Data were collected in four university campuses in Hong Kong. Subjects completed a structured questionnaire asking about the use of dating apps, sexual behaviours, and sociodemographics. Multiple linear and logistics regressions were used to explore factors associated with sexual risk behaviours. Six hundred sixty-six subjects were included in the data analysis. Factors associated with having unprotected sexual intercourse with more lifetime sexual partners included use of dating apps (β = 0.93, p<0.01), having one's first sexual intercourse before 16 years of age (β = 1.74, p<0.01), being older (β = 0.4, p<0.01), currently being in a relationship (= 0.69, p<0.05), having a monthly income at least HKD$5,000 (β = 1.34, p<0.01), being a current smoker (β = 1.52, p<0.01), and being a current drinker (β = 0.7, p<0.01). The results of a multiple logistic regression analysis found that users of dating apps (adjust odds ratio: 0.52, p<0.05) and current drinkers (adjust odds ratio: 0.40, p<0.01) were less likely to have consistent condom use. Users of dating apps (adjust odds ratio: 1.93, p<0.05), bisexual/homosexual subjects (adjust odds ratio: 2.57, p<0.01) and female subjects (adjust odds ratio: 2.00, p<0.05) were more likely not to have used condoms the last time they had sexual intercourse. The present study found a robust association between using dating apps and sexual risk behaviours, suggesting that app users had greater sexual risks. Interventions that can target app users so that they can stay safe when seeking sexual partners through dating apps should be developed.

[Eccentricity-dependent influence of amodal completion on visual search].

PubMed

Shirama, Aya; Ishiguchi, Akira

2009-06-01

Does amodal completion occur homogeneously across the visual field? Rensink and Enns (1998) found that visual search for efficiently-detected fragments became inefficient when observers perceived the fragments as a partially-occluded version of a distractor due to a rapid completion process. We examined the effect of target eccentricity in Rensink and Enns's tasks and a few additional tasks by magnifying the stimuli in the peripheral visual field to compensate for the loss of spatial resolution (M-scaling; Rovamo & Virsu, 1979). We found that amodal completion disrupted the efficient search for the salient fragments (i.e., target) even when the target was presented at high eccentricity (within 17 deg). In addition, the configuration effect of the fragments, which produced amodal completion, increased with eccentricity while the same target was detected efficiently at the lowest eccentricity. This eccentricity effect is different from a previously-reported eccentricity effect where M-scaling was effective (Carrasco & Frieder, 1997). These findings indicate that the visual system has a basis for rapid completion across the visual field, but the stimulus representations constructed through amodal completion have eccentricity-dependent properties.

Developing Medications Targeting Glutamatergic Dysfunction in Autism: Progress to Date

PubMed Central

Fung, Lawrence K.; Hardan, Antonio Y.

2015-01-01

Pharmacologic treatments targeting specific molecular mechanisms relevant for autism spectrum disorder (ASD) are beginning to emerge in early drug development. This article reviews the evidence for the disruption of glutamatergic neurotransmission in animal models of social deficits and summarizes key pre-clinical and clinical efforts in developing pharmacologic interventions based on modulation of glutamatergic systems in individuals with ASD. Understanding the pathobiology of the glutamatergic system has led to the development of new investigational treatments for individuals with ASD. Specific examples of medications that modulate the glutamatergic system in preclinical and clinical studies are described. Finally, we will discuss the limitations of current strategies and future opportunities in developing medications targeting the glutamatergic system for treating individuals with ASD. PMID:26104862

Dating and eating. Beliefs about dating foods among university students.

PubMed

Amiraian, Dana E; Sobal, Jeffery

2009-10-01

Dating is an important courtship activity in the U.S., and food consumption is part of dating events. Students use dating scripts to guide decisions and behaviors on dates, and perform scripts on dates to construct positive impression management. This study examined how students conceptualized dating foods. A questionnaire was administered in one large university class, and data from 301 students were analyzed. Students were asked to name three dating foods, three foods that are not dating foods, what makes foods dating foods, and what makes foods not dating foods. Findings revealed that both common and uncommon foods were named as dating and not dating foods. Alcoholic beverages were sometimes named as dating foods. Women often named feminine foods (considered appropriate for females) as dating foods, but men were not more likely to name masculine foods (considered appropriate for males) as dating foods. Neat and easy-to-eat foods were often named as dating foods, while pungent foods and foods causing bad breath were named as not dating foods. These findings support the conception that dating scripts guide thinking about food choices to enhance impression management. Dating food choices are important for current health and as potential precursors for long-term eating relationships like marriage.

Dating Violence and Self-Injury among Undergraduate College Students: Attitudes and Experiences

ERIC Educational Resources Information Center

Murray, Christine E.; Wester, Kelly L.; Paladino, Derrick A.

2008-01-01

An Internet-based survey about dating violence and self-injury was completed by 1,777 undergraduates. A regression analysis tested if recent dating violence victimization and perpetration experiences predicted whether participants self-injured in the past 90 days, after controlling for demographic variables and attitudes toward self-injury and…

Drinking and Dating: Examining the Link between Relationship Satisfaction, Hazardous Drinking, and Readiness-to-Change in College Dating Relationships

PubMed Central

Khaddouma, Alexander; Shorey, Ryan C.; Brasfield, Hope; Febres, Jeniimarie; Zapor, Heather; Elmquist, Joanna; Stuart, Gregory L.

2015-01-01

The present study examined the influence of relationship satisfaction on readiness-to-change alcohol use and the influence of hazardous drinking on readiness-to-change relationship issues in college student dating relationships. A sample of 219 college students in a current dating relationship (aged 18–25) completed self-report measures of dating relationship satisfaction, alcohol use, readiness-to-change alcohol use, and readiness-to-change relationship issues via an online survey from August to December 2011. Participants were grouped on the basis of their scores on measures of alcohol use (hazardous drinkers vs. nonhazardous drinkers) and relationship satisfaction (high vs. low). Results indicated that alcohol use was negatively correlated with relationship satisfaction. Furthermore, hazardous drinkers with high relationship satisfaction indicated more readiness-to-change alcohol use than hazardous drinkers with low relationship satisfaction. Alcohol problems were not related to readiness-to-change relationship issues. These findings indicate that highly satisfied dating relationships during college may positively influence readiness-to-change heavy drinking habits among college students. PMID:26997754

Project Date SMART: a Dating Violence (DV) and Sexual Risk Prevention Program for Adolescent Girls with Prior DV Exposure.

PubMed

Rizzo, Christie J; Joppa, Meredith; Barker, David; Collibee, Charlene; Zlotnick, Caron; Brown, Larry K

2018-05-01

This study assessed the initial feasibility, acceptability, and efficacy of an intervention aimed at reducing dating violence and sexual risk behavior in a sample of adolescent girls (ages 14-17) with prior exposure to physical dating violence (DV). One hundred and nine girls were randomly assigned to Date SMART (Skills to Manage Aggression in Relationships for Teens) or a Knowledge-only (KO) comparison group. Both intervention arms consisted of six, weekly 2-h sessions and one "booster" session 6 weeks later. Based on principles of cognitive behavioral therapy, the Date SMART intervention was designed to target common underlying skills deficits linked to both DV and sexual risk behavior in adolescent females: depression, self-regulation deficits, and interpersonal skills deficits. Assessments were administered at four time points (baseline, 3, 6, and 9 months). The Date SMART group was effective as reducing sexual DV involvement across the 9-month follow-up period. Both groups evidenced clinically meaningful reductions in physical, emotional, and digital DV involvement, total time in dating relationships, as well as reductions in depression. Findings indicate that delivering a DV and sexual risk prevention intervention to DV-affected adolescent girls is feasible and well-received. Furthermore, a skills-based approach that addresses the co-occurrence of DV and sexual risk behavior may be particularly useful for promoting reductions of sexual DV among high-risk adolescent girls. A future, large-scale trial with an inactive comparison condition is needed to evaluate the efficacy of Date SMART further. Clinical Trials, NCT01326195, and http://www.clinicaltrials.gov.

Liver as a target for oligonucleotide therapeutics.

PubMed

Sehgal, Alfica; Vaishnaw, Akshay; Fitzgerald, Kevin

2013-12-01

Oligonucleotide-based therapeutics are an emerging class of drugs that hold the promise for silencing "un-druggable" targets,thus creating unique opportunities for innovative medicines. As opposed to gene therapy, oligonucleotides are considered to be more akin to small molecule therapeutics because they are small,completely synthetic in origin, do not integrate into the host genome,and have a defined duration of therapeutic activity after which effects recover to baseline. They offer a high degree of specificity at the genetic level, thereby reducing off-target effects.At the same time, they provide a strategy for targeting any gene in the genome, including transcripts that produce mutated proteins.Oligonucleotide-based therapeutics include short interfering RNA (siRNA), that degrade target mRNA through RISC mediated RNAi; anti-miRs, that target miRNAs; miRNA mimics, that regulate target mRNA; antisense oligonucleotides, that may be working through RNAseH mediated mRNA decay; mRNA upregulation,by targeting long non-coding RNAs; and oligonucleotides induced alternative splicing [1]. All these approaches require some minimal degree of homology at the nucleic acid sequence level for them to be functional. The different mechanisms of action and their relevant activity are outlined in Fig. 1. Besides homology,RNA secondary structure has also been exploited in the case of ribozymes and aptamers, which act by binding to nucleic acids or proteins, respectively. While there have been many reports of gene knockdown and gene modulation in cell lines and mice with all these methods, very few have advanced to clinical stages.The main obstacle to date has been the safe and effective intracellular delivery of these compounds in higher species, including humans. Indeed, their action requires direct interaction with DNA/RNA within the target cell so even when one solves the issues of tissue and cellular access, intracellular/intranuclear location represents yet another barrier to

15 CFR 971.210 - Determination whether application is complete for further processing.

Code of Federal Regulations, 2011 CFR

2011-01-01

... COMMERCIAL RECOVERY PERMITS Applications Procedures § 971.210 Determination whether application is complete... it complete, why the additional information is necessary, and a reasonable date by which the...

20 CFR 418.3230 - When will we use your subsidy inquiry as your filing date?

Code of Federal Regulations, 2012 CFR

2012-04-01

... filing date? 418.3230 Section 418.3230 Employees' Benefits SOCIAL SECURITY ADMINISTRATION MEDICARE... oral or written inquiry about the subsidy, or partially complete an Internet subsidy application on our Web site, we will use the date of the inquiry or the date the partial Internet application was started...

20 CFR 418.3230 - When will we use your subsidy inquiry as your filing date?

Code of Federal Regulations, 2014 CFR

2014-04-01

... filing date? 418.3230 Section 418.3230 Employees' Benefits SOCIAL SECURITY ADMINISTRATION MEDICARE... oral or written inquiry about the subsidy, or partially complete an Internet subsidy application on our Web site, we will use the date of the inquiry or the date the partial Internet application was started...

20 CFR 418.3230 - When will we use your subsidy inquiry as your filing date?

Code of Federal Regulations, 2013 CFR

2013-04-01

... filing date? 418.3230 Section 418.3230 Employees' Benefits SOCIAL SECURITY ADMINISTRATION MEDICARE... oral or written inquiry about the subsidy, or partially complete an Internet subsidy application on our Web site, we will use the date of the inquiry or the date the partial Internet application was started...

Trajectories of dating violence: Differences by sexual minority status and gender.

PubMed

Martin-Storey, Alexa; Fromme, Kim

2016-06-01

The purpose of this study was to examine how sexual minority status (as assessed using both identity and behavior) was associated with trajectories of dating violence. University students from a large Southwestern university completed questions on their sexual minority identity, the gender of their sexual partners, and about experiences of dating violence for six consecutive semesters (N = 1942). Latent growth curve modeling indicated that generally, trajectories of dating violence were stable across study participation. Sexual minority identity was associated with higher initial levels of dating violence at baseline, but also with greater decreases in dating violence across time. These differences were mediated by number of sexual partners. Having same and other-sex sexual partners was associated with higher levels of dating violence at baseline, and persisted in being associated with higher levels over time. No significant gender difference was observed regarding trajectories of dating violence. Copyright © 2016 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

75 FR 35919 - Investment Company Advertising: Target Date Retirement Fund Names and Marketing

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-23

... be misleading. The amendments are intended to provide enhanced information to investors concerning... intended as the approximate year of an investor's retirement, and an investor may use the date contained in... manner reasonably calculated to draw investor attention to the information is the same presentation...

U-Th Burial Dates on Ostrich Eggshell

NASA Astrophysics Data System (ADS)

Sharp, W. D.; Fylstra, N. D.; Tryon, C. A.; Faith, J. T.; Peppe, D. J.

2015-12-01

Obtaining precise and accurate dates at archaeological sites beyond the range of radiocarbon dating is challenging but essential for understanding human origins. Eggshells of ratites (large flightless birds including ostrich, emu and others) are common in many archaeological sequences in Africa, Australia and elsewhere. Ancient eggshells are geochemically suitable for the U-Th technique (1), which has about ten times the range of radiocarbon dating (>500 rather than 50 ka), making eggshells attractive dating targets. Moreover, C and N isotopic studies of eggshell provide insights into paleovegetation and paleoprecipitation central to assessing past human-environment interactions (2,3). But until now, U-Th dates on ratite eggshell have not accounted for the secondary origin of essentially all of their U. We report a novel approach to U-Th dating of eggshell that explicitly accounts for secondary U uptake that begins with burial. Using ostrich eggshell (OES) from Pleistocene-Holocene east African sites, we have measured U and 232Th concentration profiles across OES by laser ablation ICP-MS. U commonly peaks at 10s to 100s of ppb and varies 10-fold or more across the ~2 mm thickness of OES, with gradients modulated by the layered structure of the eggshell. Common Th is high near the shell surfaces, but low in the middle "pallisade" layer of OES, making it optimal for U-Th dating. We determine U-Th ages along the U concentration gradient by solution ICP-MS analyses of two or more fractions of the pallisade layer. We then estimate OES burial dates using a simple model for diffusive uptake of uranium. Comparing such "U-Th burial dates" with radiocarbon dates for OES calcite from the same shells, we find good agreement in 7 out of 9 cases, consistent with rapid burial and confirming the accuracy of the approach. The remaining 2 eggshells have anomalous patterns of apparent ages that reveal they are unsuitable for U-Th dating, thereby providing reliability criteria innate

High School Completion Longitudinal Study

ERIC Educational Resources Information Center

Alberta Education, 2009

2009-01-01

While Alberta enjoys proven high, world-class results in student achievement, raising high school completion rates is one of the top priorities in improving the provincial education system. The 2011-12 targeted high school completion rate is 82% five years after entering Grade 10--a 2.5% increase from the current average rate of 79.5%. The purpose…

The Associations between Substance Use, Sexual Behaviors, Bullying, Deviant Behaviors, Health, and Cyber Dating Abuse Perpetration

ERIC Educational Resources Information Center

Van Ouytsel, Joris; Torres, Elizabeth; Choi, Hye Jeong; Ponnet, Koen; Walrave, Michel; Temple, Jeff R.

2017-01-01

Dating violence is an important public health concern and is considered to be a form of school violence. While digital technologies have enabled perpetrators of dating violence to target their victims online (cyber dating abuse), little is known about how this form of perpetration relates to specific adolescent risk behaviors. This brief research…

Dating Violence and Substance Use as Longitudinal Predictors of Adolescents’ Risky Sexual Behavior

PubMed Central

Shorey, Ryan C.; Fite, Paula J.; Choi, HyeJeong; Cohen, Joseph R.; Stuart, Gregory L.; Temple, Jeff R.

2015-01-01

Objective To examine dating violence perpetration and victimization (physical, psychological, and sexual) and lifetime substance use (alcohol, marijuana, and hard drugs) as longitudinal predictors of adolescents’ risky sexual behavior across one year, and to determine whether predictors varied across adolescents’ gender and ethnicity. Methods A sample of Caucasian, African American, and Hispanic male and female adolescents from 7 public high schools in Texas (N = 882) participated. Adolescents completed self-report measures of dating violence, lifetime substance use, and risky sexual behavior at baseline and, 1-year later, completed a second assessment of their risky sexual behavior. Results Path analysis demonstrated that greater physical dating violence victimization, lifetime alcohol use, lifetime marijuana use, and age (being older) were all significant predictors of risky sexual behavior at the 1-year follow-up. These results did not vary across gender or the three ethnic groups (Caucasian, African American, and Hispanic). Conclusions Overall, substance use was a longitudinal predictor of risky sexual behavior across the three ethnic groups, with physical dating violence victimization being the only type of dating violence longitudinally predicting risky sexual behavior. Prevention efforts should consider the roles of physical dating violence and substance use in preventing risky sexual behavior. PMID:25797949

Dating Violence and Substance Use as Longitudinal Predictors of Adolescents' Risky Sexual Behavior.

PubMed

Shorey, Ryan C; Fite, Paula J; Choi, HyeJeong; Cohen, Joseph R; Stuart, Gregory L; Temple, Jeff R

2015-08-01

The objectives of this study is to examine dating violence perpetration and victimization (physical, psychological, and sexual) and lifetime substance use (alcohol, marijuana, and hard drugs) as longitudinal predictors of adolescents' risky sexual behavior across 1 year and to determine whether predictors varied across adolescents' gender and ethnicity. A sample of Caucasian, African American, and Hispanic male and female adolescents from seven public high schools in Texas (N = 882) participated. Adolescents completed self-report measures of dating violence, lifetime substance use, and risky sexual behavior at baseline and, 1-year later, completed a second assessment of their risky sexual behavior. Path analysis demonstrated that greater physical dating violence victimization, lifetime alcohol use, lifetime marijuana use, and age (being older) were all significant predictors of risky sexual behavior at the 1-year follow-up. These results did not vary across gender or the three ethnic groups (Caucasian, African American, and Hispanic). Overall, substance use was a longitudinal predictor of risky sexual behavior across the three ethnic groups, with physical dating violence victimization being the only type of dating violence longitudinally predicting risky sexual behavior. Prevention efforts should consider the roles of physical dating violence and substance use in preventing risky sexual behavior.

Examining the association between bullying and adolescent concerns about teen dating violence.

PubMed

Debnam, Katrina J; Johnson, Sarah L; Bradshaw, Catherine P

2014-07-01

The school environment is an important context for understanding risk factors for teen dating violence. This study seeks to add to the growing literature base linking adolescent experiences with bullying and involvement with teen dating violence. Data were collected from 27,074 adolescents at 58 high schools via a Web-based survey. Three-level hierarchical linear models indicated that adolescents who had been bullied were more concerned about both physical and emotional dating violence among students at their school. Schools that were perceived by students as safer were rated as having lower levels of teen dating violence. Older students and male students consistently reported greater concerns about dating violence. These results suggest that adolescents who experience bullying may also have concerns about violence in teen dating relationships. Findings also indicate that schools perceived as being unsafe may be an important context for targeting dating violence prevention efforts. © 2014, American School Health Association.

Bullying as a Longitudinal Predictor of Adolescent Dating Violence

PubMed Central

Foshee, Vangie A.; Reyes, Heath Luz McNaughton; Vivolo-Kantor, Alana M.; Basile, Kathleen C.; Chang, Ling-Yin; Faris, Robert; Ennett, Susan T.

2015-01-01

Purpose One suggested approach to preventing adolescent dating violence is to prevent behavioral precursors to dating violence, such as bullying. However, no longitudinal study has examined bullying as a behavioral precursor to dating violence. In this study, longitudinal data were used to examine (1) whether direct and indirect bullying perpetration in the sixth grade predicted the onset of physical dating violence perpetration by the eighth grade and (2) whether the associations varied by sex and race/ethnicity of the adolescent. Methods Data were collected in school from sixth graders in three primarily rural counties and then again when students were in the eighth grade. Analyses were conducted with 1,154 adolescents who had not perpetrated dating violence at the sixth-grade assessment. The sample was 47% male, 29% black, and 10% of another race/ethnicity than black or white. Results Direct bullying, defined as hitting, slapping, or picking on another kid in the sixth grade, predicted the onset of physical dating violence perpetration by the eighth grade, controlling for indirect bullying and potential confounders. Although indirect bullying, defined as spreading false rumors and excluding students from friendship groups, was associated with the onset of physical dating violence perpetration in bivariate analyses, it did not predict the onset of physical dating violence when controlling for direct bullying. None of the associations examined varied by sex or race/ethnicity of the adolescents. Conclusions Our findings suggest that efforts targeted at preventing direct bullying may also prevent the onset of physical dating violence. PMID:24768162

Bullying as a longitudinal predictor of adolescent dating violence.

PubMed

Foshee, Vangie A; McNaughton Reyes, Heath Luz; Vivolo-Kantor, Alana M; Basile, Kathleen C; Chang, Ling-Yin; Faris, Robert; Ennett, Susan T

2014-09-01

One suggested approach to preventing adolescent dating violence is to prevent behavioral precursors to dating violence, such as bullying. However, no longitudinal study has examined bullying as a behavioral precursor to dating violence. In this study, longitudinal data were used to examine (1) whether direct and indirect bullying perpetration in the sixth grade predicted the onset of physical dating violence perpetration by the eighth grade and (2) whether the associations varied by sex and race/ethnicity of the adolescent. Data were collected in school from sixth graders in three primarily rural counties and then again when students were in the eighth grade. Analyses were conducted with 1,154 adolescents who had not perpetrated dating violence at the sixth-grade assessment. The sample was 47% male, 29% black, and 10% of another race/ethnicity than black or white. Direct bullying, defined as hitting, slapping, or picking on another kid in the sixth grade, predicted the onset of physical dating violence perpetration by the eighth grade, controlling for indirect bullying and potential confounders. Although indirect bullying, defined as spreading false rumors and excluding students from friendship groups, was associated with the onset of physical dating violence perpetration in bivariate analyses, it did not predict the onset of physical dating violence when controlling for direct bullying. None of the associations examined varied by sex or race/ethnicity of the adolescents. Our findings suggest that efforts targeted at preventing direct bullying may also prevent the onset of physical dating violence. Copyright © 2014 Society for Adolescent Health and Medicine. All rights reserved.

[Premature outflow tract ventricular contraction combined with complete bundle branch block: the characteristic electrocardiographic and ablation target potential features].

PubMed

Di, C Y; Wan, Z; Li, K; Ding, Y S; Lin, W H

2017-12-01

Objective: To explore the characteristics of electrocardiogram(ECG) and target potential features of premature ventricular contraction (PVC) in patients with complete left/right bundle branch block (CL/RBBB) and compare with those without CL/RBBB. Methods: A retrospective analysis was done in 8 outflow tract PVC patients with CL/RBBB, who successfully underwent radiofrequency ablation from August 2009 to June 2017. According to the bundle branch block chamber, patients were divided into the complete right bundle branch block (CRBBB) group ( n= 4) and the complete left bundle branch block (CLBBB) group ( n= 4). The control group were those who successfully underwent ablation at the same position as the above two groups but without CL/RBBB. The characteristics of ECG and target potential features were compared among groups. Results: One case in the CRBBB group was successfully ablated in the great cardiac vein with precordial R/S>1 transition at V(1) and one case in the CLBBB group was successfully ablated in the right coronary cusp with precordial R/S>1 transition at V(2), while other 6 cases were all with precordial R/S>1 transition at lead V(4). Precordial R/S>1 transition was not later than sinus rhythm (SR) in the CLBBB group. No statistical difference was found in the QRS complex duration between SR and PVC in the CL/RBBB patients [(134.38±23.80)ms vs (156.75±25.93)ms, P> 0.05], while statistical difference was shown in the control group [(92.63±5.76)ms vs (140.25±15.97)ms, P< 0.05]. Conclusion: Bundle branch block can lead to misjudgment of PVC origin with CL/RBBB during sinus rhythm, thus the origin chamber of the PVC should be determined according to the mapping and ablation result.

In Search of Teen Dating Violence Typologies.

PubMed

Reidy, Dennis E; Ball, Barbara; Houry, Debra; Holland, Kristin M; Valle, Linda A; Kearns, Megan C; Marshall, Khiya J; Rosenbluth, Barri

2016-02-01

The goal of the present research was to identify distinct latent classes of adolescents that commit teen dating violence (TDV) and assess differences on demographic, behavioral, and attitudinal correlates. Boys and girls (N = 1,149; Mage = 14.3; Grades 6-12) with a history of violence exposure completed surveys assessing six indices of TDV in the preceding 3 months. Indices of TDV included controlling behaviors, psychological TDV, physical TDV, sexual TDV, fear/intimidation, and injury. In addition, adolescents provided demographic and dating history information and completed surveys assessing attitudes condoning violence, relationship skills and knowledge, and reactive/proactive aggression. Latent class analysis indicated a three-class solution wherein the largest class of students was nonviolent on all indices ("nonaggressors") and the smallest class of students demonstrated high probability of nearly all indices of TDV ("multiform aggressors"). In addition, a third class of "emotional aggressors" existed for which there was a high probability of controlling and psychological TDV but low likelihood of any other form of TDV. Multiform aggressors were differentiated from emotional and nonaggressors on the use of self-defense in dating relationships, attitudes condoning violence, and proactive aggression. Emotional aggressors were distinguished from nonaggressors on nearly all measured covariates. Evidence indicates that different subgroups of adolescents engaging in TDV exist. In particular, a small group of youth engaging in multiple forms of TDV can be distinguished from a larger group of youth that commit acts of TDV restricted to emotional aggression (i.e., controlling and psychological) and most youth that do not engage in TDV. Published by Elsevier Inc.

Radiocarbon Dating

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buchholz, B A

Radiocarbon dating can be used to determine the age of objects that contain components that were once alive. In the case of human remains, a radiocarbon date can distinguish between a crime scene and an archeological site. Documents, museum artifacts and art objects can be dated to determine if their age is correct for the historical context. A radiocarbon date does not confirm authenticity, but it can help identify a forgery.

Dating violence experiences of lesbian, gay, bisexual, and transgender youth.

PubMed

Dank, Meredith; Lachman, Pamela; Zweig, Janine M; Yahner, Jennifer

2014-05-01

Media attention and the literature on lesbian, gay, and bisexual youth overwhelmingly focus on violence involving hate crimes and bullying, while ignoring the fact that vulnerable youth also may be at increased risk of violence in their dating relationships. In this study, we examine physical, psychological, sexual, and cyber dating violence experiences among lesbian, gay, and bisexual youth--as compared to those of heterosexual youth, and we explore variations in the likelihood of help-seeking behavior and the presence of particular risk factors among both types of dating violence victims. A total of 5,647 youth (51 % female, 74 % White) from 10 schools participated in a cross-sectional anonymous survey, of which 3,745 reported currently being in a dating relationship or having been in one during the prior year. Results indicated that lesbian, gay, and bisexual youth are at higher risk for all types of dating violence victimization (and nearly all types of dating violence perpetration), compared to heterosexual youth. Further, when looking at gender identity, transgender and female youth are at highest risk of most types of victimization, and are the most likely perpetrators of all forms of dating violence but sexual coercion, which begs further exploration. The findings support the development of dating violence prevention programs that specifically target the needs and vulnerabilities of lesbian, gay, and bisexual youth, in addition to those of female and transgender youth.

The Impacts of Using Smartphone Dating Applications on Sexual Risk Behaviours in College Students in Hong Kong

PubMed Central

2016-01-01

Dating applications (apps) on smartphones have become increasingly popular. The aim of this study was to explore the association between the use of dating apps and risky sexual behaviours. Data were collected in four university campuses in Hong Kong. Subjects completed a structured questionnaire asking about the use of dating apps, sexual behaviours, and sociodemographics. Multiple linear and logistics regressions were used to explore factors associated with sexual risk behaviours. Six hundred sixty-six subjects were included in the data analysis. Factors associated with having unprotected sexual intercourse with more lifetime sexual partners included use of dating apps (β = 0.93, p<0.01), having one’s first sexual intercourse before 16 years of age (β = 1.74, p<0.01), being older (β = 0.4, p<0.01), currently being in a relationship (= 0.69, p<0.05), having a monthly income at least HKD$5,000 (β = 1.34, p<0.01), being a current smoker (β = 1.52, p<0.01), and being a current drinker (β = 0.7, p<0.01). The results of a multiple logistic regression analysis found that users of dating apps (adjust odds ratio: 0.52, p<0.05) and current drinkers (adjust odds ratio: 0.40, p<0.01) were less likely to have consistent condom use. Users of dating apps (adjust odds ratio: 1.93, p<0.05), bisexual/homosexual subjects (adjust odds ratio: 2.57, p<0.01) and female subjects (adjust odds ratio: 2.00, p<0.05) were more likely not to have used condoms the last time they had sexual intercourse. The present study found a robust association between using dating apps and sexual risk behaviours, suggesting that app users had greater sexual risks. Interventions that can target app users so that they can stay safe when seeking sexual partners through dating apps should be developed. PMID:27828997

The Dating Anxiety Scale for Adolescents: Scale Development and Associations with Adolescent Functioning

ERIC Educational Resources Information Center

Glickman, Alissa R.; La Greca, Annette M.

2004-01-01

Given the importance of romantic and dating relationships during adolescence, the purpose of the study was to develop and evaluate the psychometric properties of the Dating Anxiety Scale for Adolescents (DAS-A). Participants were 757 high school students (56% girls, ages 15 to 18 years). Adolescents completed the DAS-A, the Social Anxiety Scale…

Preliminary Quantification of Image Color Gradient on Genesis Concentrator Silicon Carbine Target 60001

NASA Technical Reports Server (NTRS)

Allton, J. H.; Calaway, M. J.; Rodriquez, M. C.

2008-01-01

The Genesis spacecraft concentrator was a device to focus solar wind ions onto a 6-cm diameter target area, thus concentrating the solar wind by 20X [1]. The target area was comprised of 4 quadrants held in place by a gold-coated stainless steel "cross" (Fig. 1). To date, two SiC and one chemical vapor deposited (CVD) quadrants have been imaged at 5X using a Leica DM-6000M in autoscan mode. Complete imaging of SiC sample 60001 required 1036 images. The mosaic of images is shown in Fig. 2 and position of analyzed areas in Fig. 3. This mosaic imaging is part of the curatorial documentation of surface condition and mapping of contamination. Higher magnification (50X) images of selected areas of the target and individual contaminant particles are compiled into reports which may be requested from the Genesis Curator [2].

Targeted mutagenesis in Atlantic salmon (Salmo salar L.) using the CRISPR/Cas9 system induces complete knockout individuals in the F0 generation.

PubMed

Edvardsen, Rolf B; Leininger, Sven; Kleppe, Lene; Skaftnesmo, Kai Ove; Wargelius, Anna

2014-01-01

Understanding the biological function behind key proteins is of great concern in Atlantic salmon, both due to a high commercial importance and an interesting life history. Until recently, functional studies in salmonids appeared to be difficult. However, the recent discovery of targeted mutagenesis using the CRISPR/Cas9 (clustered regularly interspaced palindromic repeats/CRISPR-associated) system enables performing functional studies in Atlantic salmon to a great extent. We used the CRISPR/Cas9 system to target two genes involved in pigmentation, tyrosinase (tyr) and solute carrier family 45, member 2 (slc45a2). Embryos were assayed for mutation rates at the 17 somite stage, where 40 and 22% of all injected embryos showed a high degree of mutation induction for slc45a2 and tyr, respectively. At hatching this mutation frequency was also visible for both targeted genes, displaying a graded phenotype ranging from complete lack of pigmentation to partial loss and normal pigmentation. CRISPRslc45a2/Cas9 injected embryos showing a complete lack of pigmentation or just a few spots of pigments also lacked wild type sequences when assaying more than 80 (slc45a2) sequence clones from whole embryos. This indicates that CRISPR/Cas9 can induce double-allelic knockout in the F0 generation. However, types and frequency of indels might affect the phenotype. Therefore, the variation of indels was assayed in the graded pigmentation phenotypes produced by CRISPR/Cas9-slc45a2. The results show a tendency for fewer types of indels formed in juveniles completely lacking pigmentation compared to juveniles displaying partial pigmentation. Another interesting observation was a high degree of the same indel type in different juveniles. This study shows for the first time successful use of the CRISPR/Cas9 technology in a marine cold water species. Targeted double-allelic mutations were obtained and, though the level of mosaicism has to be considered, we demonstrate that F0 fish can be used

Longitudinal Mediators of Relations Between Family Violence and Adolescent Dating Aggression Perpetration

PubMed Central

Reyes, H. Luz McNaughton; Foshee, Vangie A.; Fortson, Beverly L.; Valle, Linda A.; Breiding, Matthew J.; Merrick, Melissa T.

2015-01-01

Few longitudinal studies have examined the pathways through which family violence leads to dating aggression. In the current study the authors used 3 waves of data obtained from 8th- and 9th-grade adolescents (N = 1,965) to examine the hypotheses that the prospective relationship between witnessing family violence and directly experiencing violence and physical dating aggression perpetration is mediated by 3 constructs: (a) normative beliefs about dating aggression (norms), (b) anger dysregulation, and (c) depression. Results from cross-lagged regression models suggest that the relationship between having been hit by an adult and dating aggression is mediated by changes in norms and anger dysregulation, but not depression. No evidence of indirect effects from witnessing family violence to dating aggression was found through any of the proposed mediators. Taken together, the findings suggest that anger dysregulation and normative beliefs are potential targets for dating abuse prevention efforts aimed at youth who have directly experienced violence. PMID:26719602

Complete Columbian mammoth mitogenome suggests interbreeding with woolly mammoths

PubMed Central

2011-01-01

Background Late Pleistocene North America hosted at least two divergent and ecologically distinct species of mammoth: the periglacial woolly mammoth (Mammuthus primigenius) and the subglacial Columbian mammoth (Mammuthus columbi). To date, mammoth genetic research has been entirely restricted to woolly mammoths, rendering their genetic evolution difficult to contextualize within broader Pleistocene paleoecology and biogeography. Here, we take an interspecific approach to clarifying mammoth phylogeny by targeting Columbian mammoth remains for mitogenomic sequencing. Results We sequenced the first complete mitochondrial genome of a classic Columbian mammoth, as well as the first complete mitochondrial genome of a North American woolly mammoth. Somewhat contrary to conventional paleontological models, which posit that the two species were highly divergent, the M. columbi mitogenome we obtained falls securely within a subclade of endemic North American M. primigenius. Conclusions Though limited, our data suggest that the two species interbred at some point in their evolutionary histories. One potential explanation is that woolly mammoth haplotypes entered Columbian mammoth populations via introgression at subglacial ecotones, a scenario with compelling parallels in extant elephants and consistent with certain regional paleontological observations. This highlights the need for multi-genomic data to sufficiently characterize mammoth evolutionary history. Our results demonstrate that the use of next-generation sequencing technologies holds promise in obtaining such data, even from non-cave, non-permafrost Pleistocene depositional contexts. PMID:21627792

Gender Role Attitudes and Male Adolescent Dating Violence Perpetration: Normative Beliefs as Moderators.

PubMed

Reyes, H Luz McNaughton; Foshee, Vangie A; Niolon, Phyllis Holditch; Reidy, Dennis E; Hall, Jeffrey E

2016-02-01

Commonly used dating violence prevention programs assume that promotion of more egalitarian gender role attitudes will prevent dating violence perpetration. Empirical research examining this assumption, however, is limited and inconsistent. The current study examined the longitudinal association between gender role attitudes and physical dating violence perpetration among adolescent boys (n = 577; 14 % Black, 5 % other race/ethnicity) and examined whether injunctive (i.e., acceptance of dating violence) and descriptive (i.e., beliefs about dating violence prevalence) normative beliefs moderated the association. As expected, the findings suggest that traditional gender role attitudes at T1 were associated with increased risk for dating violence perpetration 18 months later (T2) among boys who reported high, but not low, acceptance of dating violence (injunctive normative beliefs) at T1. Descriptive norms did not moderate the effect of gender role attitudes on dating violence perpetration. The results suggest that injunctive norms and gender role attitudes work synergistically to increase risk for dating violence perpetration among boys; as such, simultaneously targeting both of these constructs may be an effective prevention approach.

Gender Role Attitudes and Male Adolescent Dating Violence Perpetration: Normative Beliefs as Moderators

PubMed Central

Reyes, H. Luz McNaughton; Foshee, Vangie A.; Niolon, Phyllis Holditch; Reidy, Dennis E.; Hall, Jeffrey E.

2015-01-01

Commonly used dating violence prevention programs assume that promotion of more egalitarian gender role attitudes will prevent dating violence perpetration. Empirical research examining this assumption, however, is limited and inconsistent. The current study examined the longitudinal association between gender role attitudes and physical dating violence perpetration among adolescent boys (n=577; 14% Black, 5% other race/ethnicity) and examined whether injunctive (i.e., acceptance of dating violence) and descriptive (i.e., beliefs about dating violence prevalence) normative beliefs moderated the association. As expected, the findings suggest that traditional gender role attitudes at T1 were associated with increased risk for dating violence perpetration 18 months later (T2) among boys who reported high, but not low, acceptance of dating violence (injunctive normative beliefs) at T1. Descriptive norms did not moderate the effect of gender role attitudes on dating violence perpetration. The results suggest that injunctive norms and gender role attitudes work synergistically to increase risk for dating violence perpetration among boys; as such, simultaneously targeting both of these constructs may be an effective prevention approach. PMID:25831994

17 CFR 248.128 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Affiliate Marketing § 248.128 Effective date, compliance date, and prospective application. (a) Effective date. This subpart is effective September 10, 2009. (b) Mandatory compliance date. Compliance with this... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Effective date, compliance...

Charting the complete elastic properties of inorganic crystalline compounds

PubMed Central

de Jong, Maarten; Chen, Wei; Angsten, Thomas; Jain, Anubhav; Notestine, Randy; Gamst, Anthony; Sluiter, Marcel; Krishna Ande, Chaitanya; van der Zwaag, Sybrand; Plata, Jose J; Toher, Cormac; Curtarolo, Stefano; Ceder, Gerbrand; Persson, Kristin A.; Asta, Mark

2015-01-01

The elastic constant tensor of an inorganic compound provides a complete description of the response of the material to external stresses in the elastic limit. It thus provides fundamental insight into the nature of the bonding in the material, and it is known to correlate with many mechanical properties. Despite the importance of the elastic constant tensor, it has been measured for a very small fraction of all known inorganic compounds, a situation that limits the ability of materials scientists to develop new materials with targeted mechanical responses. To address this deficiency, we present here the largest database of calculated elastic properties for inorganic compounds to date. The database currently contains full elastic information for 1,181 inorganic compounds, and this number is growing steadily. The methods used to develop the database are described, as are results of tests that establish the accuracy of the data. In addition, we document the database format and describe the different ways it can be accessed and analyzed in efforts related to materials discovery and design. PMID:25984348

Dating relationships in college students with childhood-onset asthma.

PubMed

Eddington, Angelica R; Mullins, Larry L; Fedele, David A; Ryan, Jamie L; Junghans, Ashley N

2010-02-01

The current study investigated whether differences existed in dating anxiety and fear of intimacy between individuals with childhood-onset asthma and individuals without a chronic illness. Analyses were also conducted to determine if dating anxiety or fear of intimacy were predictors of health-related quality of life in individuals with asthma and healthy controls. Additionally, potential gender differences in dating anxiety and fear of intimacy in individuals with childhood-onset asthma were explored. College undergraduates at least 17 years of age who self-identified as having childhood asthma were randomly matched by age and gender to healthy control participants. Participants completed a demographic form, the Dating Anxiety Scale for Adolescents, the Fear of Intimacy Scale, and the SF-36 Health Survey, a measure of health-related quality of life. There were no significant differences between self-identified participants with asthma and matched healthy controls on the Dating Anxiety Scale or Fear of Intimacy Scale. However, dating anxiety was a significant predictor of mental health-related quality of life in participants with asthma but not in matched health controls. Fear of intimacy was not a significant predictor of mental or physical health-related quality of life in individuals with asthma. In addition, women with asthma endorsed significantly more dating anxiety and lower physical health-related quality of life than males with asthma. College students with asthma appear to experience similar levels of dating anxiety and fear of intimacy than healthy college students; however, their anxiety about dating may have a larger effect on health-related quality of life than healthy individuals. Additional examination of dating and interpersonal relationships among individuals with asthma appears warranted, particularly as it concerns possible gender differences in individuals with childhood-onset asthma.

Social Support as a Moderator between Dating Violence Victimization and Depression/Anxiety among African American and Caucasian Adolescents

ERIC Educational Resources Information Center

Holt, Melissa K.; Espelage, Dorothy L.

2005-01-01

Victimization in dating relationships was examined among 681 African American and Caucasian adolescents. Specifically, perceived social support was evaluated as a moderator between (a) physical dating violence victimization and anxiety/depression and (b) emotional abuse in dating relationships and anxiety/depression. Youth completed self-report…

In Search of Teen Dating Violence Typologies

PubMed Central

Reidy, Dennis E.; Ball, Barbara; Houry, Debra; Holland, Kristin M.; Valle, Linda A.; Kearns, Megan C.; Marshall, Khiya J.; Rosenbluth, Barri

2018-01-01

Purpose The goal of the present research was to identify distinct latent classes of adolescents that commit teen dating violence (TDV) and assess differences on demographic, behavioral, and attitudinal correlates. Methods Boys and girls (N = 1,149; Mage = 14.3; Grades 6–12) with a history of violence exposure completed surveys assessing six indices of TDV in the preceding 3 months. Indices of TDV included controlling behaviors, psychological TDV, physical TDV, sexual TDV, fear/intimidation, and injury. In addition, adolescents provided demographic and dating history information and completed surveys assessing attitudes condoning violence, relationship skills and knowledge, and reactive/proactive aggression. Results Latent class analysis indicated a three-class solution wherein the largest class of students was nonviolent on all indices (“nonaggressors”) and the smallest class of students demonstrated high probability of nearly all indices of TDV (“multiform aggressors”). In addition, a third class of “emotional aggressors” existed for which there was a high probability of controlling and psychological TDV but low likelihood of any other form of TDV. Multiform aggressors were differentiated from emotional and nonaggressors on the use of self-defense in dating relationships, attitudes condoning violence, and proactive aggression. Emotional aggressors were distinguished from nonaggressors on nearly all measured covariates. Conclusions Evidence indicates that different subgroups of adolescents engaging in TDV exist. In particular, a small group of youth engaging in multiple forms of TDV can be distinguished from a larger group of youth that commit acts of TDV restricted to emotional aggression (i.e., controlling and psychological) and most youth that do not engage in TDV. PMID:26683984

Patterns of Change in Adolescent Dating Victimization and Aggression During Middle School.

PubMed

Goncy, Elizabeth A; Farrell, Albert D; Sullivan, Terri N

2018-03-01

Although mounting evidence suggests dating victimization and aggression begin in early adolescence, little work has examined the pattern of these behaviors across this age. This longitudinal study examined trajectories of dating victimization and aggression across middle school using 12 waves of data. A sample of early adolescents (N = 1369, 52.3% girls; 83% African American; 15% Hispanic or Latino) residing in an urban, economically disadvantaged area participated in this study. Youth completed measures of dating victimization and aggression quarterly across the 3 years of middle school. Although results indicated a general trend of increasing dating victimization and aggression across middle school, variation existed for boys and girls. Specifically, girls showed increasing patterns of both, whereas boys remained relatively stable across time. Dating victimization and aggression were also highly correlated across time. These findings support the implementation and refinement of prevention programming aimed at preventing and reducing dating aggression and victimization in middle school.

Dating Violence

ERIC Educational Resources Information Center

Stader, David L.

2011-01-01

Dating violence is a form of student-on-student victimization and is a serious school safety issue. Research indicates that at a minimum, 10 percent of high school students are victims of dating violence in one form or another. Among female high school students that date, some data indicate that as many as 30 percent may be victims of dating…

The clinical development of histone deacetylase inhibitors as targeted anticancer drugs.

PubMed

Marks, Paul A

2010-09-01

Histone deacetylase (HDAC) inhibitors are being developed as a new, targeted class of anticancer drugs. This review focuses on the mechanisms of action of the HDAC inhibitors, which selectively induce cancer cell death. There are 11 zinc-dependent HDACs in humans and the biological roles of these lysine deacetylases are not completely understood. It is clear that these different HDACs are not redundant in their activity. This review focuses on the mechanisms by which HDAC inhibitors can induce transformed cell growth arrest and cell death, inhibit cell mobility and have antiangiogenesis activity. There are more than a dozen HDAC inhibitors, including hydroxamates, cyclic peptides, benzamides and fatty acids, in various stages of clinical trials and many more compounds in preclinical development. The chemically different HDAC inhibitors may target different HDACs. There are extensive preclinical studies with transformed cells in culture and tumor-bearing animal models, as well as limited clinical studies reported to date, which indicate that HDAC inhibitors will be most useful when used in combination with cytotoxic or other targeted anticancer agents.

24 CFR 213.256 - Premiums; insurance upon completion.

Code of Federal Regulations, 2010 CFR

2010-04-01

...; insurance upon completion. (a) Management and Sales Types and Investor Sponsored Projects. (1) Where the..., the mortgagee on the date of the first principal payment shall pay a second premium equal to one-half of one percent of the average outstanding principal obligation of the mortgage for the year following...

Prevalence and Correlates of the Perpetration of Cyber Dating Abuse among Early Adolescents.

PubMed

Peskin, Melissa F; Markham, Christine M; Shegog, Ross; Temple, Jeff R; Baumler, Elizabeth R; Addy, Robert C; Hernandez, Belinda; Cuccaro, Paula; Gabay, Efrat K; Thiel, Melanie; Emery, Susan Tortolero

2017-02-01

Much is known about the prevalence and correlates of dating violence, especially the perpetration of physical dating violence, among older adolescents. However, relatively little is known about the prevalence and correlates of the perpetration of cyber dating abuse, particularly among early adolescents. In this study, using a predominantly ethnic-minority sample of sixth graders who reported ever having had a boyfriend/girlfriend (n = 424, 44.2 % female), almost 15 % reported perpetrating cyber dating abuse at least once during their lifetime. Furthermore, using a cross-sectional design, across multiple levels of the socio-ecological model, the individual-level factors of (a) norms for violence for boys against girls, (b) having a current boyfriend/girlfriend, and (c) participation in bullying perpetration were correlates of the perpetration of cyber dating abuse. Collectively, the findings suggest that dating violence interventions targeting these particular correlates in early adolescents are warranted. Future studies are needed to establish causation and to further investigate the relative importance of correlates of the perpetration of cyber dating abuse among early adolescents that have been reported among older adolescents.

12 CFR 571.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Effective date, compliance date, and prospective application. 571.28 Section 571.28 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 571.28 Effective date, compliance date, and...

12 CFR 41.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Effective date, compliance date, and prospective application. 41.28 Section 41.28 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 41.28 Effective date, compliance date, and prospective...

Stability of alcohol use and teen dating violence for female youth: A latent transition analysis.

PubMed

Choi, Hye Jeong; Elmquist, JoAnna; Shorey, Ryan C; Rothman, Emily F; Stuart, Gregory L; Temple, Jeff R

2017-01-01

Alcohol use is one of the most widely accepted and studied risk factors for teen dating violence (TDV). Too little research has explored longitudinally if it is true that an adolescent's alcohol use and TDV involvement simultaneously occur. In the current study, we examined whether there were latent status based on past-year TDV and alcohol use and whether female adolescents changed their statuses of TDV and alcohol use over time. The sample consisted of 583 female youths in seven public high schools in Texas. Three waves of longitudinal data collected from 2011 to 2013 were utilised in this study. Participants completed self-report assessments of alcohol use (past-year alcohol use, number of drinks in the past month and episodic heavy drinking within the past month) and psychological and physical TDV victimisation and perpetration. Latent transition analysis was used to examine if the latent status based on TDV and alcohol use changed over time. Five separate latent statuses were identified: (i) no violence, no alcohol; (ii) alcohol; (iii) psychological violence, no alcohol; (iv) psychological violence, alcohol; and (v) physical and psychological violence, alcohol. Latent transition analysis indicated that adolescents generally remained in the same subgroup across time. This study provides evidence on the co-occurrence of alcohol use and teen dating violence, and whether teens' status based on dating violence and alcohol use are stable over time. Findings from the current study highlight the importance of targeting both TDV and substance use in intervention and prevention programs. [Choi HJ, Elmquist J, Shorey RC, Rothman EF, Stuart GL,Temple JR. Stability of alcohol use and teen dating violence for female youth: Alatent transition analysis. Drug Alcohol Rev 2017;36:80-87]. © 2017 Australasian Professional Society on Alcohol and other Drugs.

The advanced linked extended reconnaissance and targeting technology demonstration project

NASA Astrophysics Data System (ADS)

Cruickshank, James; de Villers, Yves; Maheux, Jean; Edwards, Mark; Gains, David; Rea, Terry; Banbury, Simon; Gauthier, Michelle

2007-06-01

The Advanced Linked Extended Reconnaissance & Targeting (ALERT) Technology Demonstration (TD) project is addressing key operational needs of the future Canadian Army's Surveillance and Reconnaissance forces by fusing multi-sensor and tactical data, developing automated processes, and integrating beyond line-of-sight sensing. We discuss concepts for displaying and fusing multi-sensor and tactical data within an Enhanced Operator Control Station (EOCS). The sensor data can originate from the Coyote's own visible-band and IR cameras, laser rangefinder, and ground-surveillance radar, as well as beyond line-of-sight systems such as a mini-UAV and unattended ground sensors. The authors address technical issues associated with the use of fully digital IR and day video cameras and discuss video-rate image processing developed to assist the operator to recognize poorly visible targets. Automatic target detection and recognition algorithms processing both IR and visible-band images have been investigated to draw the operator's attention to possible targets. The machine generated information display requirements are presented with the human factors engineering aspects of the user interface in this complex environment, with a view to establishing user trust in the automation. The paper concludes with a summary of achievements to date and steps to project completion.

Removing Barriers to High School Completion--Technical Report. System Improvement and Reporting.

ERIC Educational Resources Information Center

Alberta Learning, Edmonton.

The ability of every student to successfully complete high school is fundamental to continued success and quality of life. As such, Alberta Learning's 2000-2003 Business Plan has set a target for improving high school completion by 19-year-old students from 70% to 75%. A key step to achieving this target has involved completing a study of barriers…

Weight perceptions, misperceptions, and dating violence victimization among U.S. adolescents.

PubMed

Farhat, Tilda; Haynie, Denise; Summersett-Ringgold, Faith; Brooks-Russell, Ashley; Iannotti, Ronald J

2015-05-01

Dating violence is a major public health issue among youth. Overweight/obese adolescents experience peer victimization and discrimination and may be at increased risk of dating violence victimization. Furthermore, given the stigma associated with overweight/obesity, perceptions and misperceptions of overweight may be more important than actual weight status for dating violence victimization. This study examines the association of three weight indices (weight status, perceived weight, and weight perception accuracy) with psychological and physical dating violence victimization. The 2010 baseline survey of the 7-year NEXT Generation Health Study used a three-stage stratified clustered sampling design to select a nationally representative sample of U.S. 10th-grade students (n = 1,983). Participants who have had a boyfriend/girlfriend reported dating violence victimization and perceived weight. Weight status was computed from measured height/weight. Weight perception accuracy (accurate/underestimate/overestimate) was calculated by comparing weight status and perceived weight. Gender-stratified regressions examined the association of weight indices and dating violence victimization. Racial/ethnic differences were also examined. The association of weight indices with dating violence victimization significantly differed by gender. Overall, among boys, no associations were observed. Among girls, weight status was not associated with dating violence victimization, nor with number of dating violence victimization acts; however, perceived weight and weight perception accuracy were significantly associated with dating violence victimization, type of victimization, and number of victimization acts. Post hoc analyses revealed significant racial/ethnic differences. White girls who perceive themselves (accurately or not) to be overweight, and Hispanic girls who are overweight, may be at increased risk of dating violence victimization. These findings suggest a targeted approach to

77 FR 39924 - Effective Date of Requirement for Premarket Approval for Cardiovascular Permanent Pacemaker...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-06

.... FDA-2011-N-0505] Effective Date of Requirement for Premarket Approval for Cardiovascular Permanent... application (PMA) or a notice of completion of a product development protocol (PDP) for the cardiovascular...) of the FD&C Act of a PMA or notice of completion of a PDP for the cardiovascular permanent pacemaker...

Aerial view of entire LTA base after completion of both ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Aerial view of entire LTA base after completion of both LTA ship hangars. Date unknown but probably circa 1945. - Marine Corps Air Station Tustin, Northern Lighter Than Air Ship Hangar, Meffett Avenue & Maxfield Street, Tustin, Orange County, CA

The Acceptance of Dating Violence scale (ADV): Psychometric properties of the Spanish version.

PubMed

Fernández-González, Liria; Calvete, Esther; Orue, Izaskun

2017-05-01

The main aim of this study was to analyse the psychometric properties of the Spanish version of the Acceptance of Dating Violence (ADV) scale, which assesses attitudes that justify the use of aggression in adolescents’ dating relationships. A total of 1,579 high school students (49% girls) from Bizkaia (Spain), aged between 14 and 18 years (M = 15.79, SD = 1.16), completed this questionnaire along with the Irrational Beliefs Scale for Adolescents and the Conflict in Adolescent Dating Relationships Inventory. The factor analyses suggested a one-factor structure, which fits data well for both girls and boys. Moreover, the ADV showed good internal consistency (α = .83) and was related to general justification of violence and dating violence (perpetration and victimization). Boys (compared to girls) and adolescents who had had a dating relationship in the past year (compared to those who had not) displayed a higher acceptance of dating violence. The ADV is a useful, brief and easily applicable instrument for the assessment of attitudes toward dating violence.

Depression and Self-Rated Health Among Rural Women Who Experienced Adolescent Dating Abuse: A Mixed Methods Study.

PubMed

Burton, Candace W; Halpern-Felsher, Bonnie; Rehm, Roberta S; Rankin, Sally H; Humphreys, Janice C

2016-03-01

This study used mixed methods to examine the experiences and health of rural, young adult women (N = 100) who self-reported past experience of physical, emotional and verbal, sexual, and relational abuse in adolescent dating relationships. Few studies have examined the lasting health ramifications of adolescent dating abuse adolescent dating abuse in rural populations, and almost no mixed methods studies have explored adolescent dating abuse. Participants completed questionnaires on demographics, relationship behaviors, and mental health symptoms. A subsample (n = 10) of participants also completed semi-structured, in-depth interviews with the primary investigator. Results suggest that depressive symptoms and self-rating of health in these women are associated with particular kinds and severity of abusive experiences, and that adolescent dating abuse has ramifications for health and development beyond the duration of the original relationship. Self-rated health (SRH) was inversely associated with abusive behaviors in the relationship, whereas depressive symptoms were positively correlated with such behaviors. Self-rated health was also negatively correlated with depressive symptoms. The results of this study represent an important step toward establishing lifetime health risks posed by adolescent dating abuse. © The Author(s) 2014.

Visualizing Energy on Target: Molecular Dynamics Simulations

DTIC Science & Technology

2017-12-01

ARL-TR-8234 ● DEC 2017 US Army Research Laboratory Visualizing Energy on Target: Molecular Dynamics Simulations by DeCarlos E...return it to the originator. ARL-TR-8234● DEC 2017 US Army Research Laboratory Visualizing Energy on Target: Molecular Dynamics...REPORT TYPE Technical Report 3. DATES COVERED (From - To) 1 October 2015–30 September 2016 4. TITLE AND SUBTITLE Visualizing Energy on Target

Adaptive Filter Techniques for Optical Beam Jitter Control and Target Tracking

DTIC Science & Technology

2008-12-01

OPTICAL BEAM JITTER CONTROL AND TARGET TRACKING Michael J. Beerer Civilian, United States Air Force B.S., University of California Irvine, 2006...TECHNIQUES FOR OPTICAL BEAM JITTER CONTROL AND TARGET TRACKING by Michael J. Beerer December 2008 Thesis Advisor: Brij N. Agrawal Co...DATE December 2008 3. REPORT TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE Adaptive Filter Techniques for Optical Beam Jitter

Predictors of Latent Trajectory Classes of Dating Violence Victimization

PubMed Central

Brooks-Russell, Ashley; Foshee, Vangie; Ennett, Susan

2014-01-01

This study identified classes of developmental trajectories of physical dating violence victimization from grades 8 to 12 and examined theoretically-based risk factors that distinguished among trajectory classes. Data were from a multi-wave longitudinal study spanning 8th through 12th grade (n = 2,566; 51.9% female). Growth mixture models were used to identify trajectory classes of physical dating violence victimization separately for girls and boys. Logistic and multinomial logistic regressions were used to identify situational and target vulnerability factors associated with the trajectory classes. For girls, three trajectory classes were identified: a low/non-involved class; a moderate class where victimization increased slightly until the 10th grade and then decreased through the 12th grade; and a high class where victimization started at a higher level in the 8th grade, increased substantially until the 10th grade, and then decreased until the 12th grade. For males, two classes were identified: a low/non-involved class, and a victimized class where victimization increased slightly until the 9th grade, decreased until the 11th grade, and then increased again through the 12th grade. In bivariate analyses, almost all of the situational and target vulnerability risk factors distinguished the victimization classes from the non-involved classes. However, when all risk factors and control variables were in the model, alcohol use (a situational vulnerability) was the only factor that distinguished membership in the moderate trajectory class from the non-involved class for girls; anxiety and being victimized by peers (target vulnerability factors) were the factors that distinguished the high from the non-involved classes for the girls; and victimization by peers was the only factor distinguishing the victimized from the non-involved class for boys. These findings contribute to our understanding of the heterogeneity in physical dating violence victimization during

78 FR 19309 - Certain Kinesiotherapy Devices and Components Thereof; Commission Determination To Review the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-29

... Law Judge and To Extend the Target Date for Completion of the Investigation by Two Weeks to June 7... target date for completion of the investigation by two weeks to June 7, 2013. FOR FURTHER INFORMATION... determined to review the final ID in its entirety. The Commission has further determined to extend the target...

ESR dating of barite in sulphide deposits formed by the sea-floor hydrothermal activities.

PubMed

Toyoda, Shin; Fujiwara, Taisei; Uchida, Ai; Ishibashi, Jun-ichiro; Nakai, Shun'ichi; Takamasa, Asako

2014-06-01

Barite is a mineral newly found to be practically useful for electron spin resonance (ESR) dating of sulphide deposits formed by the sea-floor hydrothermal activities. The recent studies for the properties of the ESR dating signal in barite are summarised in the present paper as well as the formulas for corrections for accurate dose-rate estimation are developed including the dose-rate conversion factors, shape correction for gamma-ray dose and decay of (226)Ra. Although development of the techniques for ESR dating of barite has been completed, further comparative studies with other dating techniques such as U-Th and (226)Ra-(210)Pb dating are necessary for the technique to be widely used. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Lexical Retrieval of Nouns and Verbs in a Sentence Completion Task

ERIC Educational Resources Information Center

Abel, Alyson D.; Maguire, Mandy J.; Naqvi, Fizza M.; Kim, Angela Y.

2015-01-01

This study explored noun and verb retrieval using a sentence completion task to expand upon previous findings from picture naming tasks. Participants completed sentences missing either a target noun or verb in the final position. Non-target responses were coded for substitution type, imageability and frequency. Like picture naming, nouns and verbs…

Direct memory access transfer completion notification

DOEpatents

Archer, Charles J. , Blocksome; Michael A. , Parker; Jeffrey, J [Rochester, MN

2011-02-15

Methods, systems, and products are disclosed for DMA transfer completion notification that include: inserting, by an origin DMA on an origin node in an origin injection FIFO, a data descriptor for an application message; inserting, by the origin DMA, a reflection descriptor in the origin injection FIFO, the reflection descriptor specifying a remote get operation for injecting a completion notification descriptor in a reflection injection FIFO on a reflection node; transferring, by the origin DMA to a target node, the message in dependence upon the data descriptor; in response to completing the message transfer, transferring, by the origin DMA to the reflection node, the completion notification descriptor in dependence upon the reflection descriptor; receiving, by the origin DMA from the reflection node, a completion packet; and notifying, by the origin DMA in response to receiving the completion packet, the origin node's processing core that the message transfer is complete.

Target development for 67Cu, 82Sr radionuclide production at the RIC-80 facility

NASA Astrophysics Data System (ADS)

Panteleev, V. N.; Barzakh, A. E.; Batist, L. Kh.; Fedorov, D. V.; Ivanov, V. S.; Krotov, S. A.; Molkanov, P. L.; Moroz, F. V.; Orlov, S. Yu.; Volkov, Yu. M.

2018-01-01

A high-current cyclotron C-80 capable of producing 40-80 MeV proton beams with a current of up to 200 μA has been constructed and commissioned at PNPI (Petersburg Nuclear Physics Institute). One of the main goals of cyclotron C-80 is the production of a wide spectrum of medical radionuclides for diagnostics and therapy. To date, the project development of a radioisotope facility RIC-80 (radioisotopes at cyclotron C-80) has been completed. The feature of the project is the use of a mass-separator combined with the ion-target device for obtaining ion beams of radioisotopes with a high purity of separation that is especially important for medical applications. The first results of a new high-temperature method for extracting 82Sr and 67Cu radioisotopes from irradiated targets have been presented.

Extracting Date/Time Expressions in Super-Function Based Japanese-English Machine Translation

NASA Astrophysics Data System (ADS)

Sasayama, Manabu; Kuroiwa, Shingo; Ren, Fuji

Super-Function Based Machine Translation(SFBMT) which is a type of Example-Based Machine Translation has a feature which makes it possible to expand the coverage of examples by changing nouns into variables, however, there were problems extracting entire date/time expressions containing parts-of-speech other than nouns, because only nouns/numbers were changed into variables. We describe a method for extracting date/time expressions for SFBMT. SFBMT uses noun determination rules to extract nouns and a bilingual dictionary to obtain correspondence of the extracted nouns between the source and the target languages. In this method, we add a rule to extract date/time expressions and then extract date/time expressions from a Japanese-English bilingual corpus. The evaluation results shows that the precision of this method for Japanese sentences is 96.7%, with a recall of 98.2% and the precision for English sentences is 94.7%, with a recall of 92.7%.

Literature evidence in open targets - a target validation platform.

PubMed

Kafkas, Şenay; Dunham, Ian; McEntyre, Johanna

2017-06-06

We present the Europe PMC literature component of Open Targets - a target validation platform that integrates various evidence to aid drug target identification and validation. The component identifies target-disease associations in documents and ranks the documents based on their confidence from the Europe PMC literature database, by using rules utilising expert-provided heuristic information. The confidence score of a given document represents how valuable the document is in the scope of target validation for a given target-disease association by taking into account the credibility of the association based on the properties of the text. The component serves the platform regularly with the up-to-date data since December, 2015. Currently, there are a total number of 1168365 distinct target-disease associations text mined from >26 million PubMed abstracts and >1.2 million Open Access full text articles. Our comparative analyses on the current available evidence data in the platform revealed that 850179 of these associations are exclusively identified by literature mining. This component helps the platform's users by providing the most relevant literature hits for a given target and disease. The text mining evidence along with the other types of evidence can be explored visually through https://www.targetvalidation.org and all the evidence data is available for download in json format from https://www.targetvalidation.org/downloads/data .

12 CFR 334.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Effective date, compliance date, and prospective application. 334.28 Section 334.28 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY FAIR CREDIT REPORTING Affiliate Marketing § 334.28 Effective date...

Microprojectile Bombardment Transformation of Date Palm Using the Insecticidal Cholesterol Oxidase (ChoA) Gene.

PubMed

Allam, Mai A; Saker, Mahmoud M

2017-01-01

The overall objective of this work is to optimize the transformation system for date palm as a first step toward production of date palm clones resistant to noxious pests. A construct harboring the cholesterol oxidase (ChoA) gene, which renders plant resistance against insect attack, is introduced into embryogenic date palm callus using the PDS-1000/He particle bombardment system. The process involves the establishment of embryogenic callus cultures as well as immature embryo-derived microcalli that are used as target tissues for shooting and optimization of transformation conditions. This chapter in addition explains molecular and histochemical assays conducted to confirm gene integration and expression.

Reporting bias in completed epilepsy intervention trials: A cross-sectional analysis.

PubMed

Rayi, Appaji; Thompson, Stephanie; Gloss, David; Malhotra, Konark

2018-03-30

To explore the evidence of reporting bias among completed epilepsy intervention trials (EITs) and compliance of applicable EITs to Food and Drug Administration Amendments Act (FDAAA). We included consecutive EITs registered as completed on ClinicalTrials.gov from 2008 to 2015. Descriptive data was collected including study type, study phase, funding source, primary completion date, and result reporting date. Time to result reporting was analyzed using Kaplan-Meier estimates for two time periods (2008-2011 and 2012-2015). PubMed, Web of Science, and Google scholar databases were manually searched for publication details. Overall, 95/126 EITs (75%) reported, while remaining 31/126 (25%) did not report their results. Time to reporting was significantly lower for trials completed during 2012-2015 (16.5 months; 95% CI: 13.60-19.40; p = .002; Cohen's d = 0.68) as compared to the trials completed during 2008-2011 (25.9 months; 95% CI: 21.56-30.22). 72/126 trials were conducted in at least one U.S. center. 56/72 (78%) of the trials met the FDAAA criteria, while only 19/56 (34%) reported within the mandated one-year time frame. The lack of reporting of nearly one-quarter of completed epilepsy intervention trials suggests existence of reporting bias. As such, it should be considered an important criterion for determining risk of bias in epilepsy systematic reviews. Copyright © 2018 Elsevier B.V. All rights reserved.

75 FR 18545 - MMS Information Collection Activity: 1010-0067, Oil and Gas Well-Completion Operations, Extension...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-12

... Information Collection Activity: 1010-0067, Oil and Gas Well- Completion Operations, Extension of a Collection... requirements in the regulations under 30 CFR 250, Subpart E, ``Oil and Gas Well-Completion Operations.'' DATES... address. SUPPLEMENTARY INFORMATION: Title: 30 CFR part 250, subpart E, Oil and Gas Well-Completion...

Chemical Principles Revisited: Archaeological Dating.

ERIC Educational Resources Information Center

Rowe, M. W.

1986-01-01

Discusses methods used to date archaeological artifacts and other remains. They include: (1) nuclear dating techniques (radiocarbon dating, accelerator radiocarbon dating, thermoluminescence, and others); (2) chemical dating techniques (amino acid racemization, obsidian hydration dating, elemental content changes, and thermal analysis dating); and…

A Review of Teen Dating Violence Prevention Research: What About Hispanic Youth?

PubMed

Malhotra, Krithika; Gonzalez-Guarda, Rosa M; Mitchell, Emma M

2015-10-01

The purpose of this article is to provide a critical review of the literature on evidence-based teen dating violence (TDV) prevention programs with a particular focus on highlighting gaps in the literature with regard to prevention efforts targeting Hispanic teens. The target populations, characteristics, designs, and results of TDV prevention studies reported in the scientific literature for the last 20 years were reviewed and analyzed according to cultural and contextual factors associated with TDV among Hispanic teens. To date, three studies have focused on a predominantly Hispanic population with only one study looking at the long-term effects of a TDV intervention. There is a growing need to develop and evaluate immediate and long-term effects of TDV prevention programs that address ethnic pride, acculturation and acculturative stress, familism, and gender norms within the context of Hispanic communities (e.g., machismo and marianismo). The authors discuss the implications for research, prevention practice, and policy regarding TDV prevention for Hispanic teens. © The Author(s) 2014.

The sale of 'out of date' foods in the Republic of Palau.

PubMed

McCreadie, Kristy; Leary, Zina O

2005-03-01

'Out of date' or near out of date' foods are regularly imported into the Palau from the US and Australasia. The sale of such food products has recently been recognised by Palau as a significant public health threat for both its tourists and local population. The aim of this study is to gather baseline data on the nature and extent of expired foods sales in Palau in order to aid the development of appropriate protocols for dealing with the issue. This study used observational techniques to take a cross sectional inventory of fourteen categories of expired food products across food retailers in the urban region of Koror. The study showed that out of date foods were found across all fourteen food categories in each of the stores sampled. Many products exceeded their expiry dates by over six months. Additionally, some product lines were only sold 'out of date' suggesting that Palau is a target for off loading such food supplies. Labelling was also found to be highly problematic with food products carrying a wide range of 'out of date' descriptors, no descriptors, no date following the descriptor, or descriptors not in English. Another issue was the tendency for the retailers to freeze imported fresh products without providing a freezing date, making it impossible to tell if they were frozen before expiry. Local foods were also found to have insufficient labelling and product information.

Substance Use and Physical Dating Violence: The Role of Contextual Moderators.

PubMed

Reyes, H Luz McNaughton; Foshee, Vangie A; Tharp, Andra T; Ennett, Susan T; Bauer, Daniel J

2015-09-01

Theoretic models suggest that associations between substance use and dating violence perpetration may vary in different social contexts, but few studies have examined this proposition. The current study examined whether social control and violence in the neighborhood, peer, and family contexts moderate the associations between substance use (heavy alcohol use, marijuana, and hard drug use) and adolescent physical dating violence perpetration. Adolescents in the eighth, ninth, and tenth grades completed questionnaires in 2004 and again four more times until 2007 when they were in the tenth, 11th, and 12th grades. Multilevel analysis was used to examine interactions between each substance and measures of neighborhood, peer, and family social control and violence as within-person (time-varying) predictors of physical dating violence perpetration across eighth through 12th grade (N=2,455). Analyses were conducted in 2014. Physical dating violence perpetration increased at time points when heavy alcohol and hard drug use were elevated; these associations were weaker when neighborhood social control was higher and stronger when family violence was higher. Also, the association between heavy alcohol use and physical dating violence perpetration was weaker when teens had more-prosocial peer networks and stronger when teens' peers reported more physical dating violence. Linkages between substance use and physical dating violence perpetration depend on substance use type and levels of contextual violence and social control. Prevention programs that address substance use-related dating violence should consider the role of social contextual variables that may condition risk by influencing adolescents' aggression propensity. Copyright © 2015 American Journal of Preventive Medicine. All rights reserved.

77 FR 65907 - Certain Automated Media Library Devices; Notice of Commission Decision Remanding the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-31

...,353,581; Extension of Target Date AGENCY: U.S. International Trade Commission. ACTION: Notice. SUMMARY...'') and 6,353,581 (``the '581 patent''), and the target date for completion of the investigation is... respect to the '766 and the '581 patents, and to extend the target date. Specifically, the Commission...

76 FR 22726 - Certain Multimedia Display and Navigation Devices and Systems, Components Thereof, and Products...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-22

... Determination To Extend the Target Date; Request for Supplemental Briefing AGENCY: U.S. International Trade... determined to extend the target date for completion of the above-captioned investigation from April 18, 2011... Commission determined to review the final ID in part. Target Date: The Commission has determined to extend...

Predicting Perceptions of Date Rape: An Examination of Perpetrator Motivation, Relationship Length, and Gender Role Beliefs

ERIC Educational Resources Information Center

Angelone, David J.; Mitchell, Damon; Lucente, Lauren

2012-01-01

The purpose of the current study is to examine the influence of multiple offender motivations (including no indication of a motivation), relationship length, and gender role beliefs on perceptions of a male-on-female date rape. A sample of 348 U.S. college students read a brief vignette depicting a date rape and completed a questionnaire regarding…

Irradiation disinfestation and decontamination of Iranian dates and pistachio nuts

NASA Astrophysics Data System (ADS)

Zare, Z.; Sayhoon, M.; Maghsoudi, V.

1993-07-01

Decontamination and disinfestation effect of gamma radiation on microflora of dates and artificially infested packed dates (Mazafaty, Zard and Sayer variety) with Tribolium Confusum, Oryzaephilus Surinamensis and Ephestia Cautella in different stages studied. Treatment with 0.75 kGy dose of gamma radiation leads to complete and satisfactory insect disinfestation of dates during a storage period of 9, 20 and 35 days. This study shows that microbiological quality of Mazafaty dates can be significantly improved when they have received a gamma radiation dose of 2.5 kGy. Finally the sugar content of irradiated and unirradiated samples have compared. In this study, we have also used gamma radiation treatment for the control of microbial spoilage of pistachio nuts caused by toxigenic Aspergillus Flavus. The first sequence involved, the freshly harvested pistachio nuts inoculated with A. Flavus spores and exposed to radiation treatment, then retention of samples in a environmental chamber, set at temperature of 15-20 C at 75-80% relative humidity and stored for six months. In the second sequence during the storage period the changes in protein, lipid content of pistachio nuts have analyzed.

The Role of Acceptance of Violence Beliefs and Social Information Processing on Dating Violence Perpetration.

PubMed

Fernández-González, Liria; Calvete, Esther; Orue, Izaskun

2018-06-13

This study's main objective was to explore whether beliefs legitimizing dating violence predict dysfunctional social information processing (SIP) when adolescents deal with ambiguous dating situations, and whether this more proximal cognitive processing acts as a mediator between acceptance of violence beliefs and dating violence perpetration. Participants were 855 high school students who completed self-report measures at three time points, with a 1-year interval between them. SIP did not act as a mediator, but the emergence of anger emotions in dating conflict situations, along with aggression-justifying beliefs, were revealed as essential in explaining dating violence. Previous aggression also explained a subsequent higher anticipation of positive consequences for aggressive acts. We discuss the implications for prevention and treatment strategies with adolescents. © 2018 Society for Research on Adolescence.

Cyber dating abuse: prevalence, context, and relationship with offline dating aggression.

PubMed

Borrajo, E; Gámez-Guadix, M; Calvete, E

2015-04-01

The use of information and communication technologies (ICT) as tools to intimidate, harass, and control the partner has been, so far, little studied in the literature. The aim of this study was to determine the extension and sex differences of victimization of cyber dating abuse, as well as the context in which it occurs, and its relationship with offline psychological and physical aggressions. The sample consisted of 433 college students ages 18 to 30 years. The results showed that over 50% of the participants had been victims of some type of cyber dating abuse in the last six months. The most common behavior was the use of ICT to control the partner. Also, victims of cyber dating abuse were victimized repeatedly, an average of 23 times in the last six months. The data also showed that cyber dating abuse appear usually in a context of jealousy. Finally, the results revealed a significant relationship between cyber dating abuse and offline psychological dating aggressions. Limitations and future lines of research are discussed.

Sexting, psychological distress and dating violence among adolescents and young adults.

PubMed

Morelli, Mara; Bianchi, Dora; Baiocco, Roberto; Pezzuti, Lina; Chirumbolo, Antonio

2016-05-01

Sexting is the exchange of sexually explicit or provocative content (text messages, photos, and videos) via smartphone, Internet, or social networks. Recent evidence enlightened its relationships with several risk and aggressive behaviors. This study aimed to investigate the relationship between the amount of sexting, psychological distress, and dating violence in adolescents and young adults. The study involved 1,334 participants (68% females; mean age = 20.8) who completed a survey containing Kinsey Scale, Sexting Behavior Questionnaire, Conflict in Adolescent Dating Relationships Inventory, and General Health Questionnaire. Results showed gender and sexual orientation differences: Males (vs. females) did more sexting, while non-heterosexuals (vs. heterosexuals) were more involved in sexting. Moreover, high/moderate users of sexting committed more offline and online dating violence. Regarding psychological distress, no differences were found between high and low/moderate users of sexting. Results suggested that moderate and high use of sexting could be a risk factor for some problematic behaviors such as dating violence, even if there is not a relationship with anxiety and depression symptoms.

Artifacts in Radar Imaging of Moving Targets

DTIC Science & Technology

2012-09-01

CA, USA, 2007. [11] B. Borden, Radar imaging of airborne targets: A primer for Applied mathematicians and Physicists . New York, NY: Taylor and... Project (0704–0188) Washington DC 20503. 1. AGENCY USE ONLY (Leave blank) 2. REPORT DATE 21 September 2012 3. REPORT TYPE AND DATES COVERED...CW Continuous Wave DAC Digital to Analog Convertor DFT Discrete Fourier Transform FBP Filtered Back Projection FFT Fast Fourier Transform GPS

The Role of Parent Communication and Connectedness in Dating Violence Victimization among Latino Adolescents.

PubMed

Kast, Nicole Rebecca; Eisenberg, Marla E; Sieving, Renee E

2016-06-01

Dating violence among U.S. adolescents is a substantial concern. Previous research indicates that Latino youth are at increased risk of dating violence victimization. This secondary data analysis examined the prevalence of physical and sexual dating violence victimization among subgroups of Latino adolescents and associations of parent communication, parent caring, and dating violence victimization using data from the 2010 Minnesota Student Survey (N = 4,814). Parallel analyses were conducted for Latino-only and multiple-race Latino adolescents, stratified by gender. Multivariate logistic regression models tested associations between race/ethnicity, parent communication, perceived parent caring, and adolescent dating violence experiences. Overall, 7.2% to 16.2% of Latinos reported physical or sexual dating violence. Both types of dating violence were more prevalent among multiple-race Latinos than among Latino-only adolescents, with prevalence rates highest among multiple-race Latino females (19.8% and 19.7% for physical and sexual dating violence victimization, respectively). In multivariate models, perceived parent caring was the most important protective factor against physical and sexual dating violence among males and females. High levels of mother and father communication were associated with less physical violence victimization among males and females and with less sexual violence victimization among females. Results highlight the importance of parent communication and parent caring as buffers against dating violence victimization for Latino youth. These findings indicate potential for preventive interventions with Latino adolescents targeting family connectedness to address dating violence victimization. © The Author(s) 2015.

Ar-Ar dating techniques for terrestrial meteorite impacts

NASA Astrophysics Data System (ADS)

Kelley, S. P.

2003-04-01

The ages of the largest (>100 km) known impacts on Earth are now well characterised. However the ages of many intermediate sized craters (20-100 km) are still poorly known, often the only constraints are stratigraphic - the difference between the target rock age and the age of crater filling sediments. The largest impacts result in significant melt bodies which cool to form igneous rocks and can be dated using conventional radiometric techniques. Smaller impacts give rise to thin bands of melted rock or melt clasts intimately mixed with country rock clasts in breccia deposits, and present much more of a challenge to dating. The Ar-Ar dating technique can address a wide variety of complex and heterogeneous samples associated with meteorite impacts and obtain reasonable ages. Ar-Ar results will be presented from a series of terrestrial meteorite impact craters including Boltysh (65.17±0.64 Ma, Strangways (646±42 Ma), and St Martin (220±32 Ma) and a Late Triassic spherule bed, possibly representing distal deposits from Manicouagan (214±1 Ma) crater. Samples from the Boltysh and Strangways craters demonstrate the importance of rapid cooling upon the retention of old ages in glassy impact rocks. A Late Triassic spherule bed in SW England is cemented by both carbonate and K-feldspar cements allowing Ar-Ar dating of fine grained cement to place a mimimum age upon the age of the associated impact. An age of 214.7±2.5 Ma places the deposit with errors of the age of the Manicouagan impact, raising the possibility that it may represent a distal deposit (the deposit lay around 2000 km away from the site of the Manicouagan crater during the Late Triassic). Finally the limits of the technique will be demonstrated using an attempt to date melt rocks from the St Martin Crater in Canada.

Tobacco industry targeting youth in Argentina.

PubMed

Braun, S; Mejia, R; Ling, P M; Pérez-Stable, E J

2008-04-01

Argentina has one of the highest cigarette smoking rates among both men and women in the Americas and no legislated restrictions on tobacco industry advertising. The tobacco industry has traditionally expanded markets by targeting adolescents and young adults. The objective of this study was to determine whether and how the tobacco industry promotes cigarettes to adolescents in Argentina. We conducted a systematic search of tobacco industry documents available through the internet dated between 1995 and 2004 using standard search terms to identify marketing strategies in Argentina. A selected review of the four leading newspapers and nine magazines with reported high readership among adolescents was completed. The selected print media were searched for tobacco images and these were classified as advertisements if associated with a commercial product or as a story if not. The tobacco industry used market segmentation as a strategy to target Argentinean consumers. British American Tobacco (BAT) undertook a young adult psychographic study and classified them as "progressives", "Jurassics" or "conservatives" and "crudos" or "spoiled brats". BAT marketed Lucky Strike to the "progressives" using Hollywood movies as a vehicle. The tobacco industry also targeted their national brands to the conservatives and linked these brands with "nationalistic values" in advertising campaigns. Philip Morris promoted Marlboro by sponsoring activities directed at young people and they launched the 10 cigarettes packet as a starter vehicle. The tobacco industry used psychographic segmentation of the population and developed advertising strategies focused on youth. Tobacco control researchers and advocates must be able to address these strategies in counter-marketing interventions.

26. Photocopy of photograph dated 1930; photographer unknown; original filed ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

26. Photocopy of photograph dated 1930; photographer unknown; original filed as MR2.9/SP8/p343 in Audio-Visual Collection of Minnesota Historical Society, St. Paul; THREE-QUARTER VIEW SHOWING WEST SIDE AND SOUTH FRONT SHORTLY AFTER COMPLETION; LOOKING NORTHEAST - Northwest Airways Hangar & Administration Building, 590 Bayfield Street, St. Paul Downtown Airport (Holman), Saint Paul, Ramsey County, MN

Sexual relationship power as a mediator between dating violence and sexually transmitted infections among college women.

PubMed

Buelna, Christina; Ulloa, Emilio C; Ulibarri, Monica D

2009-08-01

This study examined relationship power as a possible mediator of the relationship between dating violence and sexually transmitted infections (STIs). The proposed mediation model was based on the theory of gender and power as well as previous research on intimate partner violence and STI risk. Survey results from a sample of 290 single, undergraduate women indicated that 85% experienced at least one form of dating violence victimization in the past year, 5.9% tested positive for an STI, and 5.2% received treatment for an STI. Results revealed that women with lower levels of sexual relationship power had higher rates of dating violence victimization and STIs; also, sexual relationship power partially mediated the relationship between dating violence victimization and STIs. Future dating violence and STI-prevention interventions targeting young women may want to use an empowerment approach to decrease their likelihood of dating violence victimization and STI risk.

The Associations Between Substance Use, Sexual Behaviors, Bullying, Deviant Behaviors, Health, and Cyber Dating Abuse Perpetration.

PubMed

Van Ouytsel, Joris; Torres, Elizabeth; Choi, Hye Jeong; Ponnet, Koen; Walrave, Michel; Temple, Jeff R

2017-04-01

Dating violence is an important public health concern and is considered to be a form of school violence. While digital technologies have enabled perpetrators of dating violence to target their victims online (cyber dating abuse), little is known about how this form of perpetration relates to specific adolescent risk behaviors. This brief research report focuses on the associations between substance use, sexual behaviors, deviant behaviors, self-reported health, and cyber dating abuse perpetration. Participants included 705 ethnically diverse adolescents ( n = 408; 57.9% female) in Southeast Texas. Having had sexual intercourse or using alcohol or drugs before having sex was significantly linked with cyber dating abuse perpetration, as was poor physical health, and substance use. Consistent with limited research, we found a link between cyber dating abuse and engagement in bullying behaviors. The discussion section includes suggestions for school nurse practice and further research.

CRISPR/Cas9: A Practical Approach in Date Palm Genome Editing

PubMed Central

Sattar, Muhammad N.; Iqbal, Zafar; Tahir, Muhammad N.; Shahid, Muhammad S.; Khurshid, Muhammad; Al-Khateeb, Abdullatif A.; Al-Khateeb, Suliman A.

2017-01-01

The genetic modifications through breeding of crop plants have long been used to improve the yield and quality. However, precise genome editing (GE) could be a very useful supplementary tool for improvement of crop plants by targeted genome modifications. Various GE techniques including ZFNs (zinc finger nucleases), TALENs (transcription activator-like effector nucleases), and most recently clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 (CRISPR-associated protein 9)-based approaches have been successfully employed for various crop plants including fruit trees. CRISPR/Cas9-based approaches hold great potential in GE due to their simplicity, competency, and versatility over other GE techniques. However, to the best of our knowledge no such genetic improvement has ever been developed in date palm—an important fruit crop in Oasis agriculture. The applications of CRISPR/Cas9 can be a challenging task in date palm GE due to its large and complex genome, high rate of heterozygosity and outcrossing, in vitro regeneration and screening of mutants, high frequency of single-nucleotide polymorphism in the genome and ultimately genetic instability. In this review, we addressed the potential application of CRISPR/Cas9-based approaches in date palm GE to improve the sustainable date palm production. The availability of the date palm whole genome sequence has made it feasible to use CRISPR/Cas9 GE approach for genetic improvement in this species. Moreover, the future prospects of GE application in date palm are also addressed in this review. PMID:28878801

CRISPR/Cas9: A Practical Approach in Date Palm Genome Editing.

PubMed

Sattar, Muhammad N; Iqbal, Zafar; Tahir, Muhammad N; Shahid, Muhammad S; Khurshid, Muhammad; Al-Khateeb, Abdullatif A; Al-Khateeb, Suliman A

2017-01-01

The genetic modifications through breeding of crop plants have long been used to improve the yield and quality. However, precise genome editing (GE) could be a very useful supplementary tool for improvement of crop plants by targeted genome modifications. Various GE techniques including ZFNs (zinc finger nucleases), TALENs (transcription activator-like effector nucleases), and most recently clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 (CRISPR-associated protein 9)-based approaches have been successfully employed for various crop plants including fruit trees. CRISPR/Cas9-based approaches hold great potential in GE due to their simplicity, competency, and versatility over other GE techniques. However, to the best of our knowledge no such genetic improvement has ever been developed in date palm-an important fruit crop in Oasis agriculture. The applications of CRISPR/Cas9 can be a challenging task in date palm GE due to its large and complex genome, high rate of heterozygosity and outcrossing, in vitro regeneration and screening of mutants, high frequency of single-nucleotide polymorphism in the genome and ultimately genetic instability. In this review, we addressed the potential application of CRISPR/Cas9-based approaches in date palm GE to improve the sustainable date palm production. The availability of the date palm whole genome sequence has made it feasible to use CRISPR/Cas9 GE approach for genetic improvement in this species. Moreover, the future prospects of GE application in date palm are also addressed in this review.

47 CFR 101.63 - Period of construction; certification of completion of construction.

Code of Federal Regulations, 2013 CFR

2013-10-01

... completion of construction. (a) Each Station, except in Multichannel Video Distribution and Data Service... this part must be in operation within 18 months from the initial date of grant. (b) For the 70 GHz, 80...

47 CFR 101.63 - Period of construction; certification of completion of construction.

Code of Federal Regulations, 2010 CFR

2010-10-01

... completion of construction. (a) Each Station, except in Multichannel Video Distribution and Data Service... this part must be in operation within 18 months from the initial date of grant. (b) For the 70 GHz, 80...

47 CFR 101.63 - Period of construction; certification of completion of construction.

Code of Federal Regulations, 2011 CFR

2011-10-01

... completion of construction. (a) Each Station, except in Multichannel Video Distribution and Data Service... this part must be in operation within 18 months from the initial date of grant. (b) For the 70 GHz, 80...

47 CFR 101.63 - Period of construction; certification of completion of construction.

Code of Federal Regulations, 2014 CFR

2014-10-01

... completion of construction. (a) Each Station, except in Multichannel Video Distribution and Data Service... this part must be in operation within 18 months from the initial date of grant. (b) For the 70 GHz, 80...

47 CFR 101.63 - Period of construction; certification of completion of construction.

Code of Federal Regulations, 2012 CFR

2012-10-01

... completion of construction. (a) Each Station, except in Multichannel Video Distribution and Data Service... this part must be in operation within 18 months from the initial date of grant. (b) For the 70 GHz, 80...

A Phenomenological Investigation of Adolescent Dating Relationships and Dating Violence Counseling Interventions

ERIC Educational Resources Information Center

Hays, Danica G.; Michel, Rebecca E.; Cole, Rebekah F.; Emelianchik, Kelly; Forman, Julia; Lorelle, Sonya; McBride, Rebecca; Sikes, April

2011-01-01

Despite the prevalence of dating violence, incidences often go unreported due to a lack of awareness among students as to appropriate dating behaviors. This phenomenology investigated how adolescents conceptualize and experience dating relationships. We explored adolescent females' definitions of healthy and abusive relationships, experiences with…

The process of adapting a universal dating abuse prevention program to adolescents exposed to domestic violence.

PubMed

Foshee, Vangie A; Dixon, Kimberly S; Ennett, Susan T; Moracco, Kathryn E; Bowling, J Michael; Chang, Ling-Yin; Moss, Jennifer L

2015-07-01

Adolescents exposed to domestic violence are at increased risk of dating abuse, yet no evaluated dating abuse prevention programs have been designed specifically for this high-risk population. This article describes the process of adapting Families for Safe Dates (FSD), an evidenced-based universal dating abuse prevention program, to this high-risk population, including conducting 12 focus groups and 107 interviews with the target audience. FSD includes six booklets of dating abuse prevention information, and activities for parents and adolescents to do together at home. We adapted FSD for mothers who were victims of domestic violence, but who no longer lived with the abuser, to do with their adolescents who had been exposed to the violence. Through the adaptation process, we learned that families liked the program structure and valued being offered the program and that some of our initial assumptions about this population were incorrect. We identified practices and beliefs of mother victims and attributes of these adolescents that might increase their risk of dating abuse that we had not previously considered. In addition, we learned that some of the content of the original program generated negative family interactions for some. The findings demonstrate the utility of using a careful process to adapt evidence-based interventions (EBIs) to cultural sub-groups, particularly the importance of obtaining feedback on the program from the target audience. Others can follow this process to adapt EBIs to groups other than the ones for which the original EBI was designed. © The Author(s) 2014.

Prevalence of teen dating victimization among a representative sample of high school students in Quebec.

PubMed

Hébert, Martine; Blais, Martin; Lavoie, Francine

2017-01-01

The present study aimed to (1) examine prevalence rates and frequency of dating violence victimization among a representative sample of Quebec high school adolescents and (2) explore possible gender differences in these rates as well as in perceived impact of victimization. A sample of 8,194 students completed questionnaires evaluating dating victimization in the past 12 months as well as perceived impacts. Results show that psychological violence is the most frequent form of dating victimization reported. Girls are more likely to report experiences of psychological, physical, threatening behaviors as well as sexual dating victimization than boys. Analyses on different indicators of the impact of victimization (i.e. feelings of fear, distress and post-traumatic stress symptoms) reveal that teenage girls are more vulnerable to sustaining more pervasive impacts than boys. The findings underscore dating violence as a prevalent public health problem. A significant number of teens report dating victimization with girls more likely than boys to perceive negative impacts associated with the coercive behaviors experienced.

40 CFR 60.1160 - Who must complete the operator training course? By when?

Code of Federal Regulations, 2012 CFR

2012-07-01

... types of employees must complete the EPA or State-approved operator training course: (1) Chief facility... initial startup. (2) December 6, 2001. (3) The date before an employee assumes responsibilities that...

40 CFR 60.1160 - Who must complete the operator training course? By when?

Code of Federal Regulations, 2010 CFR

2010-07-01

... types of employees must complete the EPA or State-approved operator training course: (1) Chief facility... initial startup. (2) December 6, 2001. (3) The date before an employee assumes responsibilities that...

40 CFR 60.1160 - Who must complete the operator training course? By when?

Code of Federal Regulations, 2014 CFR

2014-07-01

... types of employees must complete the EPA or State-approved operator training course: (1) Chief facility... initial startup. (2) December 6, 2001. (3) The date before an employee assumes responsibilities that...

40 CFR 60.1160 - Who must complete the operator training course? By when?

Code of Federal Regulations, 2011 CFR

2011-07-01

... types of employees must complete the EPA or State-approved operator training course: (1) Chief facility... initial startup. (2) December 6, 2001. (3) The date before an employee assumes responsibilities that...

40 CFR 60.1160 - Who must complete the operator training course? By when?

Code of Federal Regulations, 2013 CFR

2013-07-01

... types of employees must complete the EPA or State-approved operator training course: (1) Chief facility... initial startup. (2) December 6, 2001. (3) The date before an employee assumes responsibilities that...

Correlates of minimal dating.

PubMed

Leck, Kira

2006-10-01

Researchers have associated minimal dating with numerous factors. The present author tested shyness, introversion, physical attractiveness, performance evaluation, anxiety, social skill, social self-esteem, and loneliness to determine the nature of their relationships with 2 measures of self-reported minimal dating in a sample of 175 college students. For women, shyness, introversion, physical attractiveness, self-rated anxiety, social self-esteem, and loneliness correlated with 1 or both measures of minimal dating. For men, physical attractiveness, observer-rated social skill, social self-esteem, and loneliness correlated with 1 or both measures of minimal dating. The patterns of relationships were not identical for the 2 indicators of minimal dating, indicating the possibility that minimal dating is not a single construct as researchers previously believed. The present author discussed implications and suggestions for future researchers.

The Impact of External Resources on Conflict and Violence in Dating Relationships.

ERIC Educational Resources Information Center

Johnson, Katherine I.

Eighty-six college-aged, heterosexual couples completed questionnaires and subsequently were interviewed separately in order to test the hypothesis derived from social exchange theory that higher levels of conflict or violence will be reported in dating relationships in which one partner has fewer external resources. External resources were…

Individual and Situational Influences on Men's Responses to Dating and Social Situations

ERIC Educational Resources Information Center

Hoyt, Tim; Yeater, Elizabeth A.

2011-01-01

This study employed multilevel modeling to evaluate individual and situational influences on men's responses to hypothetical dating and social situations. Three hundred and fifty college men completed measures assessing their propensity for sexual aggression and provided written responses to 10 written vignettes, each of which was followed by four…

Dating Violence among Male and Female Youth seeking Emergency Department Care

PubMed Central

Singh, Vijay; Walton, Maureen A; Whiteside, Lauren K; Stoddard, Sarah; Epstein-Ngo, Quyen; Chermack, Stephen T; Cunningham, Rebecca M

2014-01-01

Objective To determine prevalence and correlates of dating violence, dating victimization, and dating aggression among males and females age 14–20 seeking emergency department (ED) care. Methods Systematic sampling of subjects age 14–20 seeking care at a single large academic ED between 9/2010- 3/2013. Participants completed a computerized, self-administered, cross-sectional survey of demographics, dating violence from physical abuse measures of the Conflict in Adolescent Dating Relationships Inventory, associated behaviors, and ED health service use. Separate analyses were conducted for males and females. Results 4389 youth (86.1% participation rate) were screened, and 4089 (mean age 17.5 years, 58% female) were eligible for analysis. Almost 1 in 5 females (n= 215, 18.4%) and 1 in 8 males (n= 212, 12.5%) reported past year dating violence. Of females, 10.6% reported dating victimization, and 14.6% dating aggression, while of males, 11.7% reported dating victimization, and 4.9% reported dating aggression. Multivariate analyses showed variables associated with any male dating violence were African American race (AOR 2.26, CI 1.54–3.32), alcohol misuse (AOR 1.03, CI 1.00–1.06), illicit drug misuse (AOR 2.38, CI 1.68–3.38), and depression (AOR 2.13, CI 1.46–3.10); any female dating violence was associated with African-American race (AOR 1.68, CI 1.25–2.25), public assistance (AOR 1.64, CI 1.28–2.09), grades D and below (AOR 1.62, CI 1.07–2.43), alcohol misuse (AOR 1.04, CI 1.02–1.07), illicit drug misuse (AOR 2.85, CI 2.22–3.66), depression (AOR 1.86, CI 1.42–2.44), and any past year ED visit for intentional injury (AOR 2.64, CI 1.30–5.40). Conclusions Nearly 1 of 6 male and female adolescents seeking ED care report recent dating violence, and health disparities remain among this population. Dating violence was strongly associated with alcohol, illicit drug misuse, and depression, and correlated with prior ED service utilization among female

Beyond Correlates: A Review of Risk and Protective Factors for Adolescent Dating Violence Perpetration

PubMed Central

Vagi, Kevin J.; Rothman, Emily; Latzman, Natasha E.; Tharp, Andra Teten; Hall, Diane M.; Breiding, Matthew J.

2013-01-01

Dating violence is a serious public health problem. In recent years, the U.S. Centers for Disease Control and Prevention (CDC) and other entities have made funding available to community based agencies for dating violence prevention. Practitioners who are tasked with developing dating violence prevention strategies should pay particular attention to risk and protective factors for dating violence perpetration that have been established in longitudinal studies. This has been challenging to date because the scientific literature on the etiology of dating violence is somewhat limited, and because there have been no comprehensive reviews of the literature that clearly distinguish correlates of dating violence perpetration from risk or protective factors that have been established through longitudinal research. This is problematic because prevention programs may then target factors that are merely correlated with dating violence perpetration, and have no causal influence, which could potentially limit the effectiveness of the programs. In this article, we review the literature on risk and protective factors for adolescent dating violence perpetration and highlight those factors for which temporal precedence has been established by one or more studies. This review is intended as a guide for researchers and practitioners as they formulate prevention programs. We reviewed articles published between 2000–2010 that reported on adolescent dating violence perpetration using samples from the United States or Canada. In total, 53 risk factors and six protective factors were identified from 20 studies. Next steps for etiological research in adolescent dating violence are discussed, as well as future directions for prevention program developers. PMID:23385616

Longitudinal relationships between individual and class norms supporting dating violence and perpetration of dating violence.

PubMed

Taylor, Katherine A; Sullivan, Terri N; Farrell, Albert D

2015-03-01

Dating violence is commonly perpetrated in adolescence, making it imperative to understand risk factors in order to inform prevention efforts. Although individual norms supporting dating violence are strongly related to its perpetration, few studies have examined their longitudinal impact. Moreover, the influence of class norms (i.e., norms for students in the same grade, cohort, and school) supporting dating violence on perpetration has rarely been studied. The current study examined longitudinal relationships between individual and class norms supporting dating violence and perpetration of physical and psychological dating violence. Participants were two cohorts of sixth graders from 37 schools who were in dating relationships at Wave 1 and 6 months later at Wave 2 (N = 2,022; 43% female; 52% African American, 21% Latino/a, 20% White, and 7% other). The analyses used a multilevel approach, with students represented at Level 1 and classes (n = 74) at Level 2. The models tested direct effects of Wave 1 individual and class norms supporting dating violence on subsequent changes in perpetration of dating violence at Wave 2 and the extent to which gender moderated these relationships. The findings indicated that greater individual norms supporting male dating violence predicted greater change in perpetration of physical and psychological dating violence and greater individual norms supporting female dating violence predicted greater change in perpetration of psychological dating violence. Greater class norms supporting male dating violence predicted greater change in perpetration of physical dating violence; whereas greater class norms supporting female dating violence predicted less change in perpetration of physical dating violence. These findings highlight the need to address norms in early adolescence.

VIEW OF DATE DRIVE, SHOWING DATE PALMS. NOTE TRELLIS ON ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW OF DATE DRIVE, SHOWING DATE PALMS. NOTE TRELLIS ON TYPE 11 FACILITY, FACILITY 808. VIEW FACING NORTHWEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Intersection of Acacia Road and Brich Circle, Pearl City, Honolulu County, HI

76 FR 28211 - Proposed Information Collection; Comment Request; Survey of Housing Starts, Sales, and Completions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-16

... Housing Starts, Sales, and Completions AGENCY: U.S. Census Bureau, Commerce. ACTION: Notice. SUMMARY: The... and Budget (OMB) clearance of the Survey of Housing Starts, Sales and Completions, also known as the... system, etc.), and if applicable, date of sale, sales price, and type of financing. The SOC provides...

The Realities of Date Rape.

ERIC Educational Resources Information Center

Presley, Cara; Watson, Jennifer; Williams, Audrey R.

This poster presentation addresses the issue of date rape, specifically in the college environment. Highlighted are date rape statistics, demographics, and date rape drugs. Also discussed are date rape warnings and prevention strategies. It is concluded that college and university administrators must place the issue of date rape and acquaintance…

Radiometric Dating Does Work!

ERIC Educational Resources Information Center

Dalrymple, G. Brent

2000-01-01

Discusses the accuracy of dating methods and creationist arguments that radiometric dating does not work. Explains the Manson meteorite impact and the Pierre shale, the ages of meteorites, the K-T tektites, and dating the Mount Vesuvius eruption. (Author/YDS)

Substance Use as a Longitudinal Predictor of the Perpetration of Teen Dating Violence

ERIC Educational Resources Information Center

Temple, Jeff R.; Shorey, Ryan C.; Fite, Paula; Stuart, Gregory L.; Le, Vi Donna

2013-01-01

The prevention of teen dating violence is a major public health priority. However, the dearth of longitudinal studies makes it difficult to develop programs that effectively target salient risk factors. Using a school-based sample of ethnically diverse adolescents, this longitudinal study examined whether substance use (alcohol, marijuana, and…

The fate of completed intentions.

PubMed

Anderson, Francis T; Einstein, Gilles O

2017-04-01

The goal of this research was to determine whether and how people deactivate prospective memory (PM) intentions after they have been completed. One view proposes that PM intentions can be deactivated after completion, such that they no longer come to mind and interfere with current tasks. Another view is that now irrelevant completed PM intentions exhibit persisting activation, and continue to be retrieved. In Experiment 1, participants were given a PM intention embedded within the ongoing task during Phase 1, after which participants were told either that the PM task had been completed or suspended until later. During Phase 2, participants were instructed to perform only the ongoing task and were periodically prompted to report their thoughts. Critically, the PM targets from Phase 1 reappeared in Phase 2. All of our measures, including thoughts reported about the PM task, supported the existence of persisting activation. In Experiment 2, we varied conditions that were expected to mitigate persisting activation. Despite our best attempts to promote deactivation, we found evidence for the persistence of spontaneous retrieval in all groups after intentions were completed. The theoretical and practical implications of this potential dark side to spontaneous retrieval are discussed.

16 CFR 680.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2013 CFR

2013-01-01

... REPORTING ACT AFFILIATE MARKETING § 680.28 Effective date, compliance date, and prospective application. (a... part shall not prohibit you from using eligibility information that you receive from an affiliate to...

12 CFR 41.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2013 CFR

2013-01-01

... TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 41.28 Effective date, compliance date, and prospective... an affiliate to make solicitations to a consumer if the bank receives such information prior to...

12 CFR 41.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2014 CFR

2014-01-01

... TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 41.28 Effective date, compliance date, and prospective... an affiliate to make solicitations to a consumer if the bank receives such information prior to...

16 CFR 680.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2012 CFR

2012-01-01

... REPORTING ACT AFFILIATE MARKETING § 680.28 Effective date, compliance date, and prospective application. (a... part shall not prohibit you from using eligibility information that you receive from an affiliate to...

16 CFR 680.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2011 CFR

2011-01-01

... REPORTING ACT AFFILIATE MARKETING § 680.28 Effective date, compliance date, and prospective application. (a... part shall not prohibit you from using eligibility information that you receive from an affiliate to...

16 CFR 680.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2014 CFR

2014-01-01

... REPORTING ACT AFFILIATE MARKETING § 680.28 Effective date, compliance date, and prospective application. (a... part shall not prohibit you from using eligibility information that you receive from an affiliate to...

16 CFR 680.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REPORTING ACT AFFILIATE MARKETING § 680.28 Effective date, compliance date, and prospective application. (a... part shall not prohibit you from using eligibility information that you receive from an affiliate to...

12 CFR 41.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2012 CFR

2012-01-01

... TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 41.28 Effective date, compliance date, and prospective... an affiliate to make solicitations to a consumer if the bank receives such information prior to...

12 CFR 41.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2011 CFR

2011-01-01

... TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 41.28 Effective date, compliance date, and prospective... an affiliate to make solicitations to a consumer if the bank receives such information prior to...

12 CFR 571.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2014 CFR

2014-01-01

... FAIR CREDIT REPORTING Affiliate Marketing § 571.28 Effective date, compliance date, and prospective... affiliate to make solicitations to a consumer if you receive such information prior to October 1, 2008. For...

12 CFR 571.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2012 CFR

2012-01-01

... THE TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 571.28 Effective date, compliance date, and... receive from an affiliate to make solicitations to a consumer if you receive such information prior to...

12 CFR 571.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2011 CFR

2011-01-01

... THE TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 571.28 Effective date, compliance date, and... receive from an affiliate to make solicitations to a consumer if you receive such information prior to...

12 CFR 571.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2013 CFR

2013-01-01

... FAIR CREDIT REPORTING Affiliate Marketing § 571.28 Effective date, compliance date, and prospective... affiliate to make solicitations to a consumer if you receive such information prior to October 1, 2008. For...

Molecular characterization of Syrian date palm cultivars using plasmid-like DNA markers.

PubMed

Haider, N; Nabulsi, I

2012-02-01

Date palm (Phoenix dactylifera L.) is one of the most important domesticated fruit trees in the Near East and North African countries. This tree has been, for several decades, in serious threat of being completely destroyed by the "Bayoud" disease caused by Fusarium oxysporum f. sp. albedinis. In this study, 18 Syrian date palm cultivars and four male trees were analyzed according to the identity of mitochondrial plasmid-like DNAs. A PCR strategy that employs plasmid-like DNAs-specific primer pair was used. These primers amplify a product of either 373-bp or 265-bp that corresponds to the S-(Bayoud-susceptible) or the R-plasmid (Bayoud-resistant), respectively. Generated data revealed that only six cultivars ('Medjool', 'Ashrasi', 'Gish Rabi', 'Khineze', and yellow- and red-'Kabkab') have the S-plasmid, suggesting their susceptibility to the fusariosis, while the remaining 12 cultivars and the four male trees contain the R-plasmid, suggesting their resistance to the fusariosis. The PCR process applied here has been proved efficient for the rapid screening for the presence of the S and R DNAs in Syrian date palm. PCR markers developed in this study could be useful for the screening of date palm lines growing in the field. The availability of such diagnostic tool for plasmid characterization in date palm would also be of great importance in establishing propagation and breeding programs of date palm in Syria.

Prediction of accrual closure date in multi-center clinical trials with discrete-time Poisson process models.

PubMed

Tang, Gong; Kong, Yuan; Chang, Chung-Chou Ho; Kong, Lan; Costantino, Joseph P

2012-01-01

In a phase III multi-center cancer clinical trial or a large public health study, sample size is predetermined to achieve desired power, and study participants are enrolled from tens or hundreds of participating institutions. As the accrual is closing to the target size, the coordinating data center needs to project the accrual closure date on the basis of the observed accrual pattern and notify the participating sites several weeks in advance. In the past, projections were simply based on some crude assessment, and conservative measures were incorporated in order to achieve the target accrual size. This approach often resulted in excessive accrual size and subsequently unnecessary financial burden on the study sponsors. Here we proposed a discrete-time Poisson process-based method to estimate the accrual rate at time of projection and subsequently the trial closure date. To ensure that target size would be reached with high confidence, we also proposed a conservative method for the closure date projection. The proposed method was illustrated through the analysis of the accrual data of the National Surgical Adjuvant Breast and Bowel Project trial B-38. The results showed that application of the proposed method could help to save considerable amount of expenditure in patient management without compromising the accrual goal in multi-center clinical trials. Copyright © 2012 John Wiley & Sons, Ltd.

Physical dating violence among adolescents and young adults with alcohol misuse.

PubMed

Singh, Vijay; Epstein-Ngo, Quyen; Cunningham, Rebecca M; Stoddard, Sarah A; Chermack, Stephen T; Walton, Maureen A

2015-08-01

This study determined prevalence and correlates of physical dating violence (victimization or aggression) among male and female youth with alcohol misuse and seeking emergency department (ED) care. Patients age 14-20 seeking care at a single large university-based ED completed a computerized, self-administered, cross-sectional survey. Measures included demographics, alcohol and substance use, mental health problems, health service use, peer influences, parent support, and community involvement. Bivariate and multivariate regression assessed physical dating violence correlates. Among 842 male and female youth seeking ED care who screened positive for alcohol misuse, 22.3% (n=188) reported dating violence in the past year. Multivariate analyses showed variables associated with dating violence were female gender (AOR 2.17, CI 1.46-3.22), Caucasian race (AOR 0.59, CI 0.37-0.93), receipt of public assistance (AOR 1.82, CI 1.16-2.87), AUDIT Score (AOR 1.06, CI 1.02-1.10), older age of drinking onset (AOR 0.86, CI 0.77-0.96), suicidal ideation or attempt (AOR 1.95, CI 1.13-3.37), frequency of ED visits (AOR 1.22, CI 1.05-1.46), negative peer influences (AOR 1.05, CI 1.01-1.10), and positive peer influences (AOR 0.86, CI 0.80-0.93). Nearly 1 in 4 youth with alcohol misuse seeking ED care report dating violence. Key correlates of dating violence included alcohol use severity, suicidal ideation, ED services, and peer influences. Evidence-based dating violence interventions addressing these correlates are needed for youth with alcohol misuse seeking ED care. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

17 CFR 160.18 - Effective date; compliance date; transition rule.

Code of Federal Regulations, 2010 CFR

2010-04-01

..., by that date, you have established a system for providing an initial notice to all new customers and... agreements. Until March 31, 2003, a contract that you have entered into with a nonaffiliated third party to... date; transition rule. 160.18 Section 160.18 Commodity and Securities Exchanges COMMODITY FUTURES...

Dates fruits classification using SVM

NASA Astrophysics Data System (ADS)

Alzu'bi, Reem; Anushya, A.; Hamed, Ebtisam; Al Sha'ar, Eng. Abdelnour; Vincy, B. S. Angela

2018-04-01

In this paper, we used SVM in classifying various types of dates using their images. Dates have interesting different characteristics that can be valuable to distinguish and determine a particular date type. These characteristics include shape, texture, and color. A system that achieves 100% accuracy was built to classify the dates which can be eatable and cannot be eatable. The built system helps the food industry and customer in classifying dates depending on specific quality measures giving best performance with specific type of dates.

Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π-Π Stacking Stabilized Polymeric Micelles

PubMed Central

Shi, Yang; van der Meel, Roy; Theek, Benjamin; Blenke, Erik Oude; Pieters, Ebel H.E.; Fens, Marcel H.A.M.; Ehling, Josef; Schiffelers, Raymond M.; Storm, Gert; van Nostrum, Cornelus F.; Lammers, Twan; Hennink, Wim E.

2015-01-01

Treatment of cancer patients with taxane-based chemotherapeutics, such as paclitaxel (PTX), is complicated by their narrow therapeutic index. Polymeric micelles are attractive nanocarriers for tumor-targeted delivery of PTX, as they can be tailored to encapsulate large amounts of hydrophobic drugs and achieve prolonged circulation kinetics. As a result, PTX deposition in tumors is increased while drug exposure to healthy tissues is reduced. However, many PTX-loaded micelle formulations suffer from low stability and fast drug release in the circulation, limiting their suitability for systemic drug targeting. To overcome these limitations, we have developed paclitaxel (PTX)-loaded micelles which are stable without chemical crosslinking and covalent drug attachment. These micelles are characterized by excellent loading capacity and strong drug retention, attributed to π-π stacking interaction between PTX and the aromatic groups of the polymer chains in the micellar core. The micelles are based on methoxy poly(ethylene glycol)-b-(N-(2-benzoyloxypropyl) methacrylamide) (mPEG-b-p(HPMAm-Bz)) block copolymers, which improved the pharmacokinetics and the biodistribution of PTX, and substantially increased PTX tumor accumulation (by more than 2000%; as compared to Taxol® or control micellar formulations). Improved biodistribution and tumor accumulation were confirmed by hybrid μCT-FMT imaging using near-infrared labeled micelles and payload. The PTX-loaded micelles were well tolerated at different doses while they induced complete tumor regression in two different xenograft models (i.e. A431 and MDA-MB-468). Our findings consequently indicate that π-π stacking-stabilized polymeric micelles are promising carriers to improve the delivery of highly hydrophobic drugs to tumors and to increase their therapeutic index. PMID:25831471

76 FR 50663 - Effective Date of Requirement for Premarket Approval for Three Class III Preamendments Devices

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-16

... completion of a PDP is not filed by the latter of the two dates, and no IDE is in effect, the device is... availability of a preamendments class III devices strategy document. The strategy document set forth FDA's... approved PMA or a declared completed PDP is required to be in effect for any such devices on or before 180...

45. Photographic copy of photograph, dated October 1970 (original print ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

45. Photographic copy of photograph, dated October 1970 (original print in possession of CSSD-HO, Huntsville, AL). Photographer unknown. Aerial mid-construction view (northeast to southwest) of perimeter acquisition radar building and par power plant. These buildings were approximately 33% complete at the time - Stanley R. Mickelsen Safeguard Complex, Perimeter Acquisition Radar Building, Limited Access Area, between Limited Access Patrol Road & Service Road A, Nekoma, Cavalier County, ND

Dating and Physical Violence.

ERIC Educational Resources Information Center

Heritage, Jeannette; Carlton, Carol C.; West, Beryl

Physical aggression in dating relationships has become a serious problem. Because knowledge of violence in marital relationships has expanded to include dating relationships, some of the attitudes of college students toward violent behavior in dating relationships are examined here. Also discussed are ways in which demographics and life history…

Enhancing Targeted Therapy for Myeloproliferative Neoplasms

DTIC Science & Technology

2013-10-01

Myeloproliferative Neoplasms PRINCIPAL INVESTIGATOR: Gary W. Reuther CONTRACTING...2. REPORT TYPE Annual 3. DATES COVERED 30 2012-2 2013 4. TITLE AND SUBTITLE Enhancing Targeted Therapy for Myeloproliferative Neoplasms ...AVAILABILITY STATEMENT Approved for Public Release; Distribution Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT Myeloproliferative neoplasms

ADM. Change House (TAN606) as completed. Camera facing northerly. Note ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

ADM. Change House (TAN-606) as completed. Camera facing northerly. Note proximity to shielding berm. Part of hot shop (A&M Building, TAN-607) at left of view beyond berm. Date: October 29, 1954. INEEL negative no. 12705 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

Tobacco industry targeting youth in Argentina

PubMed Central

Braun, S; Mejia, R; Ling, P M; Pérez-Stable, E J

2013-01-01

Background/aim Argentina has one of the highest cigarette smoking rates among both men and women in the Americas and no legislated restrictions on tobacco industry advertising. The tobacco industry has traditionally expanded markets by targeting adolescents and young adults. The objective of this study was to determine whether and how the tobacco industry promotes cigarettes to adolescents in Argentina. Methods We conducted a systematic search of tobacco industry documents available through the internet dated between 1995 and 2004 using standard search terms to identify marketing strategies in Argentina. A selected review of the four leading newspapers and nine magazines with reported high readership among adolescents was completed. The selected print media were searched for tobacco images and these were classified as advertisements if associated with a commercial product or as a story if not. Results The tobacco industry used market segmentation as a strategy to target Argentinean consumers. British American Tobacco (BAT) undertook a young adult psychographic study and classified them as “progressives”, “Jurassics” or “conservatives” and “crudos” or “spoiled brats”. BAT marketed Lucky Strike to the “progressives” using Hollywood movies as a vehicle. The tobacco industry also targeted their national brands to the conservatives and linked these brands with “nationalistic values” in advertising campaigns. Philip Morris promoted Marlboro by sponsoring activities directed at young people and they launched the 10 cigarettes packet as a starter vehicle. Conclusions The tobacco industry used psychographic segmentation of the population and developed advertising strategies focused on youth. Tobacco control researchers and advocates must be able to address these strategies in counter-marketing interventions. PMID:18299308

49 CFR 40.73 - How is the collection process completed?

Code of Federal Regulations, 2011 CFR

2011-10-01

...'s presence. (1) Direct the employee to read and sign the certification statement on Copy 2 (Step 5... the employee refuses to sign the CCF or to provide date of birth, printed name, or telephone numbers... appropriate place. (2) Complete the chain of custody on the CCF (Step 4) by printing your name (note: you may...

In-Situ Dating on Mars: The Potential of OSL Dating

NASA Technical Reports Server (NTRS)

Blair, M. W.; Kalchgruber, R.; Yukihara, E. G.; Bulur, E.; Kim, S. S.; McKeever, W. S.

2004-01-01

More and more evidence is being accumulated that Mars has experienced aeolian, fluvial, and periglacial activity in the (relatively) recent past [1, 2, 3]. However, the temporal scale on which these processes took place is very poorly constrained since crater counting has errors comparable to the age for younger terrains (approx. 1 Ma). Consequently, many researchers have called for methods to establish the climatic and geomorphic history of Mars [4]. Lepper and McKeever [5] suggested developing optically stimulated luminescence (OSL) dating techniques for in-situ dating of martian sediments. Electron paramagnetic resonance (EPR) is closely related to OSL and could easily be incorporated on the same instrument platform [6]. These two methods can aid in developing a geological and climatic history of Mars over the last approx. one million years. Since the initial investigations, work has been carried out to develop OSL instrumentation and dating procedures that are suitable to the unique challenges of the martian environment. In this paper, we highlight the advances made in this project, focusing on OSL dating principles, assumptions, and procedures.

The Complete Sequence of a Human Parainfluenzavirus 4 Genome

PubMed Central

Yea, Carmen; Cheung, Rose; Collins, Carol; Adachi, Dena; Nishikawa, John; Tellier, Raymond

2009-01-01

Although the human parainfluenza virus 4 (HPIV4) has been known for a long time, its genome, alone among the human paramyxoviruses, has not been completely sequenced to date. In this study we obtained the first complete genomic sequence of HPIV4 from a clinical isolate named SKPIV4 obtained at the Hospital for Sick Children in Toronto (Ontario, Canada). The coding regions for the N, P/V, M, F and HN proteins show very high identities (95% to 97%) with previously available partial sequences for HPIV4B. The sequence for the L protein and the non-coding regions represent new information. A surprising feature of the genome is its length, more than 17 kb, making it the longest genome within the genus Rubulavirus, although the length is well within the known range of 15 kb to 19 kb for the subfamily Paramyxovirinae. The availability of a complete genomic sequence will facilitate investigations on a respiratory virus that is still not completely characterized. PMID:21994536

WFIRST: Exoplanet Target Selection and Scheduling with Greedy Optimization

NASA Astrophysics Data System (ADS)

Keithly, Dean; Garrett, Daniel; Delacroix, Christian; Savransky, Dmitry

2018-01-01

We present target selection and scheduling algorithms for missions with direct imaging of exoplanets, and the Wide Field Infrared Survey Telescope (WFIRST) in particular, which will be equipped with a coronagraphic instrument (CGI). Optimal scheduling of CGI targets can maximize the expected value of directly imaged exoplanets (completeness). Using target completeness as a reward metric and integration time plus overhead time as a cost metric, we can maximize the sum completeness for a mission with a fixed duration. We optimize over these metrics to create a list of target stars using a greedy optimization algorithm based off altruistic yield optimization (AYO) under ideal conditions. We simulate full missions using EXOSIMS by observing targets in this list for their predetermined integration times. In this poster, we report the theoretical maximum sum completeness, mean number of detected exoplanets from Monte Carlo simulations, and the ideal expected value of the simulated missions.

Dating violence among male and female youth seeking emergency department care.

PubMed

Singh, Vijay; Walton, Maureen A; Whiteside, Lauren K; Stoddard, Sarah; Epstein-Ngo, Quyen; Chermack, Stephen T; Cunningham, Rebecca M

2014-10-01

We determine prevalence and correlates of dating violence, dating victimization, and dating aggression among male and female patients aged 14 to 20 years seeking emergency department (ED) care. This was a systematic sampling of subjects aged 14 to 20 years seeking care at a single large academic ED between September 2010 and March 2013. Participants completed a computerized, self-administered, cross-sectional survey of demographics, dating violence from physical abuse measures of the Conflict in Adolescent Dating Relationships Inventory, associated behaviors, and ED health service use. Separate analyses were conducted for male and female patients. Four thousand three hundred eighty-nine youths (86.1% participation rate) were screened, and 4,089 (mean age 17.5 years; 58% female patients) were eligible for analysis. Almost 1 in 5 female patients (n=215; 18.4%) and 1 in 8 male patients (n=212; 12.5%) reported past-year dating violence. Of female patients, 10.6% reported dating victimization and 14.6% dating aggression, whereas of male patients, 11.7% reported dating victimization and 4.9% reported dating aggression. Multivariate analyses showed that variables associated with any male dating violence were black race (adjusted odds ratio [AOR] 2.26; 95% CI 1.54 to 3.32), alcohol misuse (AOR 1.03; 95% CI 1.00 to 1.06), illicit drug use (AOR 2.38; 95% CI 1.68 to 3.38), and depression (AOR 2.13; 95% CI 1.46 to 3.10); any female dating violence was associated with black race (AOR 1.68; 95% CI 1.25 to 2.25), public assistance (AOR 1.64; 95% CI 1.28 to 2.09), grades D and below (AOR 1.62; 95% CI 1.07 to 2.43), alcohol misuse (AOR 1.04; 95% CI 1.02 to 1.07), illicit drug use (AOR 2.85; 95% CI 2.22 to 3.66), depression (AOR 1.86; 95% CI 1.42 to 2.44), and any past year ED visit for intentional injury (AOR 2.64; 95% CI 1.30 to 5.40). Nearly 1 of 6 male and female patients aged 14 to 20 years and seeking ED care report recent dating violence, and health disparities remain among

The association between smartphone dating applications and college students' casual sex encounters and condom use.

PubMed

Choi, Edmond P H; Wong, Janet Y H; Lo, Herman H M; Wong, Wendy; Chio, Jasmine H M; Fong, Daniel Y T

2016-10-01

This study aims to explore the association between using smartphone dating applications (apps) and having unprotected sex with a casual sex partner. This is a cross-sectional study. Students were recruited from four university campuses in Hong Kong by convenience sampling. Subjects completed a structured questionnaire asking about the use of dating apps, sexual history and socio-demographic information. Multiple logistic regressions were used to explore the association between using dating apps and having unprotected sex with a casual sex partner. Six hundred and sixty-six subjects were included in the analysis. Users of dating apps were more likely to have had unprotected sex with a casual sex partner the last time they engaged in sexual intercourse (aOR: 10.06). Using dating apps for more than 12 months was associated with having a casual sex partner in the last sexual intercourse (aOR: 3.21), as well as having unprotected sex with that casual partner (aOR: 13.56). We found a robust association between using dating apps and having unprotected sex with a casual sex partner, implying that using dating apps is an emerging sexual risk factor. We recommend that interventions promoting the safe use of dating apps should be implemented. Copyright © 2016 Elsevier B.V. All rights reserved.

Cancer and Stroma-Targeted Immunotherapy with a Genetically Modified DC Vaccine

DTIC Science & Technology

2013-05-01

of Medicine One Baylor Plaza Houston, TX 77030 REPORT DATE: May 2013 TYPE OF REPORT: Final PREPARED FOR: U.S. Army Medical...information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE May ...2013 2. REPORT TYPE Final report 3. DATES COVERED 01 May 2010 - 30 April 2013 4. TITLE AND SUBTITLE Cancer and Stroma-Targeted Immunotherapy

An Evaluation of Two Dating Violence Prevention Programs on a College Campus.

PubMed

Peterson, Kerry; Sharps, Phyllis; Banyard, Victoria; Powers, Ráchael A; Kaukinen, Catherine; Gross, Deborah; Decker, Michele R; Baatz, Carrie; Campbell, Jacquelyn

2016-03-13

Dating violence is a serious and prevalent public health problem that is associated with numerous negative physical and psychological health outcomes, and yet there has been limited evaluation of prevention programs on college campuses. A recent innovation in campus prevention focuses on mobilizing bystanders to take action. To date, bystander programs have mainly been compared with no treatment control groups raising questions about what value is added to dating violence prevention by focusing on bystanders. This study compared a single 90-min bystander education program for dating violence prevention with a traditional awareness education program, as well as with a no education control group. Using a quasi-experimental pre-test/post-test design with follow-up at 2 months, a sample of predominately freshmen college students was randomized to either the bystander (n = 369) or traditional awareness (n = 376) dating violence education program. A non-randomized control group of freshmen students who did not receive any education were also surveyed (n = 224). Students completed measures of attitudes, including rape myth acceptance, bystander efficacy, and intent to help as well as behavioral measures related to bystander action and victimization. Results showed that the bystander education program was more effective at changing attitudes, beliefs, efficacy, intentions, and self-reported behaviors compared with the traditional awareness education program. Both programs were significantly more effective than no education. The findings of this study have important implications for future dating violence prevention educational programming, emphasizing the value of bystander education programs for primary dating violence prevention among college students. © The Author(s) 2016.

Dating Violence among College Students

ERIC Educational Resources Information Center

Iconis, Rosemary

2013-01-01

Dating violence is a significant problem on college campuses. More than one-fifth of the undergraduate dating population are physically abused by their dating partners and an even greater percentage are psychologically abused. Researchers have identified risk factors for college student dating violence. Preventive interventions are strongly…

7 CFR 987.5 - Dates.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 8 2011-01-01 2011-01-01 false Dates. 987.5 Section 987.5 Agriculture Regulations of... Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE DOMESTIC DATES PRODUCED OR PACKED IN RIVERSIDE COUNTY, CALIFORNIA Order Regulating Handling Definitions § 987.5 Dates. Dates means the Deglet...

7 CFR 987.5 - Dates.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Dates. 987.5 Section 987.5 Agriculture Regulations of... Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE DOMESTIC DATES PRODUCED OR PACKED IN RIVERSIDE COUNTY, CALIFORNIA Order Regulating Handling Definitions § 987.5 Dates. Dates means the Deglet...

Direct dating of archaeological pottery by compound-specific 14C analysis of preserved lipids.

PubMed

Stott, Andrew W; Berstan, Robert; Evershed, Richard P; Bronk-Ramsey, Christopher; Hedges, Robert E M; Humm, Martin J

2003-10-01

A methodology is described demonstrating the utility of the compound-specific 14C technique as a direct means of dating archaeological pottery. The method uses automated preparative capillary gas chromatography employing wide-bore capillary columns to isolate individual compounds from lipid extracts of archaeological potsherds in high purity (>95%) and amounts (>200 microg) sufficient for radiocarbon dating using accelerator mass spectrometry (AMS). A protocol was developed and tested on n-alkanes and n-carboxylic acids possessing a broad range of 14C ages. Analytical blanks and controls allowed background 14C measurements to be assessed and potential sources of errors to be detected, i.e., contamination with modern or dead 14C, isotopic fraction effects, etc. A "Russian doll" method was developed to transfer isolated target compounds onto tin powder/capsules prior to combustion and AMS analyses. The major advantage of the compound-specific technique is that 14C dates obtained for individual compounds can be directly linked to the commodities processed in the vessels during their use, e.g., animal fats. The compound-specific 14C dating protocol was validated on a suite of ancient pottery whose predicted ages spanned a 5000-year date range. Initial results indicate that meaningful correlations can be obtained between the predicted date of pottery and that of the preserved lipids. These findings constitute an important step forward to the direct dating of archaeological pottery.

Elemental analysis using ED-XRF and 14C dating of Cuman wall paintings samples

NASA Astrophysics Data System (ADS)

Brocchieri, J.; Sabbarese, C.; Marzaioli, F.; Passariello, I.; Terrasi, F.; De Maio, C.; Ferrara, L.

2018-04-01

The aim of the present research was to analyse pigments and mortars of fresco fragments located at Cuma (Naples, Italy). The ED-XRF technique and 14C dating were used to establish the nature of the pigments and the age of mortars, respectively. ED-XRF results allowed to determine the elemental composition of the pigments that identified the colours and, hence, the historical period of completion. The 14C dating, applied to mortars using a particular preparation, provided results that are in accordance with the archaeological information within the 2σ interval range.

Adolescents' Anxiety in Dating Situations: The Potential Role of Friends and Romantic Partners

ERIC Educational Resources Information Center

La Greca, Annette M.; Mackey, Eleanor Race

2007-01-01

This study examined adolescents' interpersonal functioning, including the qualities of their closest friendships and romantic relationships, as predictors of dating/heterosocial anxiety. An ethnically diverse sample of 781 adolescents (57% girls; ages 15-19 years) completed measures that assessed the number and type of close friends, the presence…

Perpetration of Adolescent Dating Relationship Abuse: The Role of Conditional Tolerance for Violence and Friendship Factors.

PubMed

Mumford, Elizabeth A; Taylor, Bruce G; Giordano, Peggy C

2017-02-01

Research has pointed to the salience of friendships in predicting abuse in adolescent dating relationships. The current study investigates the perpetration of physical and sexual dating abuse as predicted by individual conditional tolerance for dating abuse within the context of friendship behaviors and group characteristics. Using two waves of the National Survey of Teen Relationships and Intimate Violence (STRiV; N = 511 daters aged 12-18 years), we investigated the effects of baseline individual tolerance for hitting dating partners and friendship factors on perpetration of physical and sexual adolescent dating abuse (ADA) approximately 1 year later. Conditional tolerance for hitting boyfriends was associated with ADA perpetration in the absence of friendship characteristics. Daters who reported recent discussion of a problem with friends and female daters who named all-girl friendship groups were more likely to report ADA perpetration. Close friendships are an avenue for preventing ADA perpetration. Furthermore, ADA perpetration may be reduced by targeting conditional tolerance for violence particularly against male partners within female friendship groups.

Procedures for Completion and Use of FAA Form 8130-3, Airworthiness Approval Tag

DOT National Transportation Integrated Search

1994-01-03

This order revises the procedures contained in Order 8130.21, Completion and Use of Federal Aviation Administration (FAA) Form 8130-3, Airworthiness Approval Tag (herein referred to as "the form") dated June 21, 1991. : Specifically, this revision co...

Total-Evidence Dating under the Fossilized Birth–Death Process

PubMed Central

Zhang, Chi; Stadler, Tanja; Klopfstein, Seraina; Heath, Tracy A.; Ronquist, Fredrik

2016-01-01

Bayesian total-evidence dating involves the simultaneous analysis of morphological data from the fossil record and morphological and sequence data from recent organisms, and it accommodates the uncertainty in the placement of fossils while dating the phylogenetic tree. Due to the flexibility of the Bayesian approach, total-evidence dating can also incorporate additional sources of information. Here, we take advantage of this and expand the analysis to include information about fossilization and sampling processes. Our work is based on the recently described fossilized birth–death (FBD) process, which has been used to model speciation, extinction, and fossilization rates that can vary over time in a piecewise manner. So far, sampling of extant and fossil taxa has been assumed to be either complete or uniformly at random, an assumption which is only valid for a minority of data sets. We therefore extend the FBD process to accommodate diversified sampling of extant taxa, which is standard practice in studies of higher-level taxa. We verify the implementation using simulations and apply it to the early radiation of Hymenoptera (wasps, ants, and bees). Previous total-evidence dating analyses of this data set were based on a simple uniform tree prior and dated the initial radiation of extant Hymenoptera to the late Carboniferous (309 Ma). The analyses using the FBD prior under diversified sampling, however, date the radiation to the Triassic and Permian (252 Ma), slightly older than the age of the oldest hymenopteran fossils. By exploring a variety of FBD model assumptions, we show that it is mainly the accommodation of diversified sampling that causes the push toward more recent divergence times. Accounting for diversified sampling thus has the potential to close the long-discussed gap between rocks and clocks. We conclude that the explicit modeling of fossilization and sampling processes can improve divergence time estimates, but only if all important model aspects

Total-Evidence Dating under the Fossilized Birth-Death Process.

PubMed

Zhang, Chi; Stadler, Tanja; Klopfstein, Seraina; Heath, Tracy A; Ronquist, Fredrik

2016-03-01

Bayesian total-evidence dating involves the simultaneous analysis of morphological data from the fossil record and morphological and sequence data from recent organisms, and it accommodates the uncertainty in the placement of fossils while dating the phylogenetic tree. Due to the flexibility of the Bayesian approach, total-evidence dating can also incorporate additional sources of information. Here, we take advantage of this and expand the analysis to include information about fossilization and sampling processes. Our work is based on the recently described fossilized birth-death (FBD) process, which has been used to model speciation, extinction, and fossilization rates that can vary over time in a piecewise manner. So far, sampling of extant and fossil taxa has been assumed to be either complete or uniformly at random, an assumption which is only valid for a minority of data sets. We therefore extend the FBD process to accommodate diversified sampling of extant taxa, which is standard practice in studies of higher-level taxa. We verify the implementation using simulations and apply it to the early radiation of Hymenoptera (wasps, ants, and bees). Previous total-evidence dating analyses of this data set were based on a simple uniform tree prior and dated the initial radiation of extant Hymenoptera to the late Carboniferous (309 Ma). The analyses using the FBD prior under diversified sampling, however, date the radiation to the Triassic and Permian (252 Ma), slightly older than the age of the oldest hymenopteran fossils. By exploring a variety of FBD model assumptions, we show that it is mainly the accommodation of diversified sampling that causes the push toward more recent divergence times. Accounting for diversified sampling thus has the potential to close the long-discussed gap between rocks and clocks. We conclude that the explicit modeling of fossilization and sampling processes can improve divergence time estimates, but only if all important model aspects

Targeting Stromal Recruitment by Prostate Cancer Cells

DTIC Science & Technology

2006-03-01

Ensinger, C., Tumer , Z., Tommerup, N. et al.: Hedgehog signaling in small-cell lung cancer : frequent in vivo but a rare event in vitro. Lung Cancer , 52...W81XWH-04-1-0157 TITLE: Targeting Stromal Recruitment by Prostate Cancer Cells PRINCIPAL INVESTIGATOR: Jingxian Zhang, Ph.D...DATES COVERED (From - To) 15 Feb 2004 – 14 Feb 2006 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Targeting Stromal Recruitment by Prostate Cancer

12 CFR Appendix A to Part 203 - Form and Instructions for Completion of HMDA Loan/Application Register

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 2 2011-01-01 2011-01-01 false Form and Instructions for Completion of HMDA..., numerals, or a combination of both. 2. Date Application Received a. Enter the date the loan application was... (any loan other than FHA, VA, FSA, or RHS loans) Code 2—FHA-insured (Federal Housing Administration...

High-Frequency Jet Ventilation for Complete Target Immobilization and Reduction of Planning Target Volume in Stereotactic High Single-Dose Irradiation of Stage I Non-Small Cell Lung Cancer and Lung Metastases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fritz, Peter, E-mail: p.h.fritz@t-online.d; Kraus, Hans-Joerg; Muehlnickel, Werner

2010-09-01

Purpose: To demonstrate the feasibility of complete target immobilization by means of high-frequency jet ventilation (HFJV); and to show that the saving of planning target volume (PTV) on the stereotactic body radiation therapy (SBRT) under HFJV, compared with SBRT with respiratory motion, can be predicted with reliable accuracy by computed tomography (CT) scans at peak inspiration phase. Methods and Materials: A comparison regarding different methods for defining the PTV was carried out in 22 patients with tumors that clearly moved with respiration. A movement span of the gross tumor volume (GTV) was defined by fusing respiration-correlated CT scans. The PTVmore » enclosed the GTV positions with a safety margin throughout the breathing cycle. To create a PTV from CT scans acquired under HFJV, the same margins were drawn around the immobilized target. In addition, peak inspiration phase CT images (PIP-CTs) were used to approximate a target immobilized by HFJV. Results: The resulting HFJV-PTVs were between 11.6% and 45.4% smaller than the baseline values calculated as respiration-correlated CT-PTVs (median volume reduction, 25.4%). Tentative planning by means of PIP-CT PTVs predicted that in 19 of 22 patients, use of HFJV would lead to a reduction in volume of {>=}20%. Using this threshold yielded a positive predictive value of 0.89, as well as a sensitivity of 0.94 and a specificity of 0.5. Conclusions: In all patients, SBRT under HFJV provided a reliable immobilization of the GTVs and achieved a reduction in PTVs, regardless of patient compliance. Tentative planning facilitated the selection of patients who could better undergo radiation in respiratory standstill, both with greater accuracy and lung protection.« less

Date Palm Germplasm

USDA-ARS?s Scientific Manuscript database

This book chapter reviews date palm genetic resources and their conservation. Date palm (Phoenix dactylifera) is an important food crop in the Middle East and North Africa. Its center of origin and diversity most probably is the area near Iraq/Iran. From there, it spread throughout its present range...

New Directions for Preventing Dating Violence in Adolescence: The Study of Gender Models

PubMed Central

Santoro, Chiara; Martínez-Ferrer, Belén; Monreal Gimeno, Carmen; Musitu, Gonzalo

2018-01-01

Dating violence is a huge transcultural and alarming phenomenon, directly linked with endless discrimination against women. The latest research on dating violence in adolescence shows how dating violence is persistent and common in the adolescent period as well and pinpoints the origin of gender violence from first adolescent relationships. This element takes us to considerate how recent gender violence studies and policies, increased also thanks to international efforts on this issue, are not bringing expected results, especially among young people. This mini-review aims to analyze the main characteristics of current gender studies and policies on dating violence, focusing on percentages with a woman-centered approach, which stresses the consequences of gender violence. Other gender studies, that consider gender as a relational product, stress the importance of integrating the analysis of gender models as a key instrument to understand the main causes of dating violence, providing new elements to develop effective policies against dating violence. Indeed, gender models of femininity and masculinity are based on a binary system, which is also a reciprocal recognition and identity system: gender models define female and male characteristics, roles, stereotypes, and expectation, being complementary and foreclosing at the same time. Recent studies on gender relationships, especially among the youth, allows us to propose a new dialog between dating violence studies and gender model studies, underling the need of a complete and complex understanding of gender structure, and of its tensions and contradictions, to put an end to gender and dating violence, through effective programs. PMID:29946282

31 CFR 536.302 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 536.302 Section 536... Definitions § 536.302 Effective date. The term effective date refers to the effective date of the applicable... of specially designated narcotics traffickers designated after that date, the earlier of the date on...

31 CFR 595.302 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 595.302 Section 595... § 595.302 Effective date. The term effective date refers to the effective date of the applicable... of specially designated terrorists designated after that date, the earlier of the date on which a...

17 CFR 248.128 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2014 CFR

2014-04-01

... on Affiliate Marketing § 248.128 Effective date, compliance date, and prospective application. (a... this subpart do not prohibit you from using eligibility information that you receive from an affiliate to make a marketing solicitation to a consumer if you receive such information prior to January 1...

12 CFR 717.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 7 2014-01-01 2014-01-01 false Effective date, compliance date, and prospective application. 717.28 Section 717.28 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION... eligibility information when such information is placed into a common database and is accessible by you. ...

12 CFR 717.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 7 2013-01-01 2013-01-01 false Effective date, compliance date, and prospective application. 717.28 Section 717.28 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION... eligibility information when such information is placed into a common database and is accessible by you. ...

12 CFR 717.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Effective date, compliance date, and prospective application. 717.28 Section 717.28 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION... eligibility information when such information is placed into a common database and is accessible by you. ...

12 CFR 717.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 7 2012-01-01 2012-01-01 false Effective date, compliance date, and prospective application. 717.28 Section 717.28 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION... eligibility information when such information is placed into a common database and is accessible by you. ...

12 CFR 717.28 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Effective date, compliance date, and prospective application. 717.28 Section 717.28 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION... eligibility information when such information is placed into a common database and is accessible by you. ...

Radiocarbon dating of the human eye lens crystallines reveal proteins without carbon turnover throughout life.

PubMed

Lynnerup, Niels; Kjeldsen, Henrik; Heegaard, Steffen; Jacobsen, Christina; Heinemeier, Jan

2008-01-30

Lens crystallines are special proteins in the eye lens. Because the epithelial basement membrane (lens capsule) completely encloses the lens, desquamation of aging cells is impossible, and due to the complete absence of blood vessels or transport of metabolites in this area, there is no subsequent remodelling of these fibers, nor removal of degraded lens fibers. Human tissue ultimately derives its (14)C content from the atmospheric carbon dioxide. The (14)C content of the lens proteins thus reflects the atmospheric content of (14)C when the lens crystallines were formed. Precise radiocarbon dating is made possible by comparing the (14)C content of the lens crystallines to the so-called bomb pulse, i.e. a plot of the atmospheric (14)C content since the Second World War, when there was a significant increase due to nuclear-bomb testing. Since the change in concentration is significant even on a yearly basis this allows very accurate dating. Our results allow us to conclude that the crystalline formation in the lens nucleus almost entirely takes place around the time of birth, with a very small, and decreasing, continuous formation throughout life. The close relationship may be further expressed as a mathematical model, which takes into account the timing of the crystalline formation. Such a life-long permanence of human tissue has hitherto only been described for dental enamel. In confront to dental enamel it must be held in mind that the eye lens is a soft structure, subjected to almost continuous deformation, due to lens accommodation, yet its most important constituent, the lens crystalline, is never subject to turnover or remodelling once formed. The determination of the (14)C content of various tissues may be used to assess turnover rates and degree of substitution (for example for brain cell DNA). Potential targets may be nervous tissues in terms of senile or pre-senile degradation, as well as other highly specialised structures of the eyes. The precision with

17 CFR 248.128 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Affiliate Marketing § 248.128 Effective date, compliance date, and prospective application. (a) Effective... subpart do not prohibit you from using eligibility information that you receive from an affiliate to make a marketing solicitation to a consumer if you receive such information prior to January 1, 2010. For...

17 CFR 248.128 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Affiliate Marketing § 248.128 Effective date, compliance date, and prospective application. (a) Effective... subpart do not prohibit you from using eligibility information that you receive from an affiliate to make a marketing solicitation to a consumer if you receive such information prior to January 1, 2010. For...

17 CFR 248.128 - Effective date, compliance date, and prospective application.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Affiliate Marketing § 248.128 Effective date, compliance date, and prospective application. (a) Effective... subpart do not prohibit you from using eligibility information that you receive from an affiliate to make a marketing solicitation to a consumer if you receive such information prior to January 1, 2010. For...

Targeting the Oxytocin System to Treat Addictive Disorders: Rationale and Progress to Date

PubMed Central

Lee, Mary R.; Rohn, Matthew C.H.; Tanda, Gianluigi; Leggio, Lorenzo

2016-01-01

The neuropeptide oxytocin plays a role in reward, stress, social affiliation, learning and memory processes. As such there is increasing interest in oxytocin as a potential treatment for addictions. The oxytocin system is itself altered by acute or chronic exposure to drugs of abuse. A large number of preclinical studies in rodents have investigated the effect of oxytocin on various drug-induced behaviors to determine whether oxytocin can reverse the neuroadaptations occurring with repeated drug and alcohol use. In addition, the mechanisms by which oxytocin acts to modify the behavioral response to drugs of abuse are beginning to be understood. More recently, a few small clinical studies have been conducted in cocaine, cannabis and alcohol dependence. This review summarizes the preclinical as well as clinical literature to date on the oxytocin system and its relevance to drug and alcohol addiction. PMID:26932552

45 CFR 96.49 - Due date for receipt of all information required for completion of tribal applications for the...

Code of Federal Regulations, 2010 CFR

2010-10-01

... for completion of tribal applications for the low-income home energy assistance block grants. 96.49 Section 96.49 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION BLOCK GRANTS... required for completion of tribal applications for the low-income home energy assistance block grants...

Effects of Cognitive Distortions on the Link Between Dating Violence Exposure and Substance Problems in Clinically Hospitalized Youth.

PubMed

Miller, Adam Bryant; Williams, Caitlin; Day, Catherine; Esposito-Smythers, Christianne

2017-06-01

The purpose of the present study was to examine whether cognitive distortions (e.g., cognitive errors; negative views of self, world, and future) influence the association between dating violence and problematic substance use behaviors in a sample of psychiatrically hospitalized adolescents. Participants included 155 adolescents, aged 13-17 years, who had initiated dating. Adolescents completed measures of dating violence, substance-related problems (alcohol and marijuana), and cognitive distortions. Logistic regressions were conducted to examine the direct and interactive effects of dating violence exposure and cognitive distortions on likelihood of recent problematic substance use. Results suggested a main effect of dating violence on problematic alcohol and other drug use as well as an interactive effect of dating violence and cognitive distortions. Specifically, the relationship between dating violence and odds of substance-related problems was higher among those with greater (vs. fewer) cognitive distortions. Study results suggest the need for careful screening of cognitive distortions among adolescent dating violence victims, particularly those in mental health treatment. © 2016 Wiley Periodicals, Inc.

Effects of Cognitive Distortions on the Link Between Dating Violence Exposure and Substance Problems in Clinically Hospitalized Youth

PubMed Central

Miller, Adam Bryant; Williams, Caitlin; Esposito-Smythers, Christianne

2016-01-01

Purpose The purpose of the present study was to examine whether cognitive distortions (e.g., cognitive errors; negative views of self, world, and future) influence the association between dating violence and problematic substance use behaviors in a sample of psychiatrically hospitalized adolescents. Methods Participants included 155 adolescents, ages 13 to 17, who had initiated dating. Adolescents completed measures of dating violence, substance related problems, (alcohol and marijuana), and cognitive distortions. Results Logistic regressions were conducted to examine the direct and interactive effects of dating violence exposure and cognitive distortions on likelihood of recent problematic substance use. Results suggested a main effect of dating violence on problematic alcohol and other drug use as well as an interactive effect of dating violence and cognitive distortions. Specifically, the relationship between dating violence and odds of substance related problems were higher among those with greater (vs. fewer) cognitive distortions. Conclusions Study results suggest the need for careful screening of cognitive distortions among adolescent dating violence victims, particularly those in mental health treatment. PMID:27552530

Kepler Planet Detection Metrics: Per-Target Flux-Level Transit Injection Tests of TPS for Data Release 25

NASA Technical Reports Server (NTRS)

Burke, Christopher J.; Catanzarite, Joseph

2017-01-01

the recovered signals can be further classified as planet candidates or false positives in the exact same manner as detections from the nominal (i.e., observed) pipeline run (Twicken et al., 2016, Thompson et al., in preparation). To date, the PLTI test has been the standard means of measuring pipeline completeness averaged over large samples of targets (Christiansen et al., 2015, 2016; Christiansen, 2017). However, since the PLTI test uses only one injection per target, it does not elucidate individual-target variations in pipeline completeness due to differences in stellar properties or astrophysical variability. Thus, we developed the FLTI test to provide a numerically efficient way to fully map individual targets and explore the performance of the pipeline in greater detail. The FLTI tests thereby allow a thorough validation of the pipeline completeness models (such as window function (Burke and Catanzarite, 2017a), detection efficiency (Burke Catanzarite, 2017b), etc.) across the spectrum of Kepler targets (i.e., various astrophysical phenomena and differences in instrumental noise). Tests during development of the FLTI capability revealed that there are significant target-to-target variations in the detection efficiency.

Topology, divergence dates, and macroevolutionary inferences vary between different tip-dating approaches applied to fossil theropods (Dinosauria).

PubMed

Bapst, D W; Wright, A M; Matzke, N J; Lloyd, G T

2016-07-01

Dated phylogenies of fossil taxa allow palaeobiologists to estimate the timing of major divergences and placement of extinct lineages, and to test macroevolutionary hypotheses. Recently developed Bayesian 'tip-dating' methods simultaneously infer and date the branching relationships among fossil taxa, and infer putative ancestral relationships. Using a previously published dataset for extinct theropod dinosaurs, we contrast the dated relationships inferred by several tip-dating approaches and evaluate potential downstream effects on phylogenetic comparative methods. We also compare tip-dating analyses to maximum-parsimony trees time-scaled via alternative a posteriori approaches including via the probabilistic cal3 method. Among tip-dating analyses, we find opposing but strongly supported relationships, despite similarity in inferred ancestors. Overall, tip-dating methods infer divergence dates often millions (or tens of millions) of years older than the earliest stratigraphic appearance of that clade. Model-comparison analyses of the pattern of body-size evolution found that the support for evolutionary mode can vary across and between tree samples from cal3 and tip-dating approaches. These differences suggest that model and software choice in dating analyses can have a substantial impact on the dated phylogenies obtained and broader evolutionary inferences. © 2016 The Author(s).

Laser ``M'egajoule'' cryogenic target program: from target fabrication to conformation of the deuterium-tritium ice layer

NASA Astrophysics Data System (ADS)

Collier, Rémy; Durut, Frédéric; Reneaume, Benoît; Chicane, Cédric; Théobald, Marc; Breton, Olivier; Martin, Michel; Fleury, Emmanuel; Vincent-Viry, Olivier; Bachelet, Franck; Jeannot, Laurent; Geoffray, Isabelle; Botrel, Ronan; Dauteuil, Christophe; Hermerel, Cyril; Choux, Alexandre; Bednarczyk, Sophie; Legaie, Olivier

2008-11-01

For the French inertial confinement fusion (ICF) experiments, cryogenic target assemblies (CTAs) for the LMJ program are manufactured and filled at CEA Valduc (Dijon) in the cryogenic targets filling station (IRCC). They will be moved at about 20 K into a transport cryostat for cryogenic targets and will be driven from CEA/Valduc to CEA/CESTA (Bordeaux). Cryogenic targets will then be transferred by several cryogenic grippers on the cryogenic target positioner before shots. The CTA has to meet severe specifications and involves a lot of challenging tasks for its manufacture. To fill CTAs by permeation with deuterium-tritium (DT), the IRCC need to meet strict thermal, mechanical and dimensional specifications. To obtain a good combustion yield, a very homogenous DT ice layer and very smooth roughness at 1.5 K below the DT triple point are also required. This paper deals with the up to date main issues in the different fields of the LMJ cryogenic target program.

31 CFR 551.302 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 551.302 Section 551....302 Effective date. The term effective date refers to the effective date of the applicable... the date of actual or constructive notice that such person's property and interests in property are...

31 CFR 548.302 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 548.302 Section 548....302 Effective date. The term effective date refers to the effective date of the applicable... pursuant to § 548.201(a), the earlier of the date of actual or constructive notice that such person's...

31 CFR 541.302 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 541.302 Section 541... § 541.302 Effective date. The term effective date refers to the effective date of the applicable....201(a)(2), the earlier of the date on which either actual notice or constructive notice is received of...

21 CFR 1312.25 - Expiration date.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Expiration date. 1312.25 Section 1312.25 Food and... SUBSTANCES Exportation of Controlled Substances § 1312.25 Expiration date. An export permit shall not be valid after the date specified therein, which date shall conform to the expiration date specified in the...

31 CFR 537.303 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 537.303 Section 537....303 Effective date. The term effective date refers to the effective date of the applicable... property of persons designated pursuant to § 537.201(a)(2), the earlier of the date on which either actual...

21 CFR 1312.25 - Expiration date.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Expiration date. 1312.25 Section 1312.25 Food and... SUBSTANCES Exportation of Controlled Substances § 1312.25 Expiration date. An export permit shall not be valid after the date specified therein, which date shall conform to the expiration date specified in the...

Manpower Targets and Educational Investments

ERIC Educational Resources Information Center

Ritzen, Jo M.

1976-01-01

Discusses the use of quadratic programming to calculate the optimal distribution of educational investments required to closely approach manpower targets when financial resources are insufficient to meet manpower targets completely. Demonstrates use of the quadratic programming approach by applying it to the training of supervisory technicians in…

History of dating violence and the association with late adolescent health

PubMed Central

2013-01-01

Background The present investigation expands upon prior studies by examining the relationship between health in late adolescence and the experience of physical/sexual and non-physical dating violence victimization, including dating violence types that are relevant to today’s adolescents (e.g., harassment via email and text messaging). We examined the relationship between physical/sexual and non-physical dating violence victimization from age 13 to 19 and health in late adolescence/early adulthood. Methods The sample comprised 585 subjects (ages 18 to 21; mean age, 19.8, SD = 1.0) recruited from The Ohio State University who completed an online survey to assess: 1) current health (depression, disordered eating, binge drinking, smoking, and frequent sexual behavior); and 2) dating violence victimization from age 13 to 19 (retrospectively assessed using eight questions covering physical, sexual, and non-physical abuse, including technology-related abuse involving stalking/harassment via text messaging and email). Multivariable models compared health indicators in never-exposed subjects to those exposed to physical/sexual or non-physical dating violence only. The multivariable models were adjusted for age and other non-dating abuse victimization (bullying; punched, kicked, choked by a parent/guardian; touched in a sexual place, forced to touch someone sexually). Results In adjusted analyses, compared to non-exposed females, females with physical/sexual dating violence victimization were at increased risk of smoking (prevalence ratio = 3.95); depressive symptoms (down/hopeless, PR = 2.00; lost interest, PR = 1.79); eating disorders (using diet aids, PR = 1.98; fasting, PR = 4.71; vomiting to lose weight, PR = 4.33); and frequent sexual behavior (5+ intercourse and oral sex partners, PR = 2.49, PR = 2.02; having anal sex, PR = 2.82). Compared to non-exposed females, females with non-physical dating violence only were at increased risk of smoking (PR = 3

31 CFR 594.302 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 594.302 Section 594... Definitions § 594.302 Effective date. The term effective date refers to the effective date of the applicable... to § 594.201(a)(2), (a)(3), or (a)(4), the earlier of the date on which is received actual or...

31 CFR 576.303 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 576.303 Section 576... General Definitions § 576.303 Effective date. The term effective date refers to the effective date of the... blocked pursuant to § 576.201(a)(2) or (a)(3), the earlier of the date of actual or constructive notice...

31 CFR 543.303 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 543.303 Section 543... Definitions § 543.303 Effective date. The term effective date refers to the effective date of the applicable... § 543.201(a)(2), the earlier of the date of actual or constructive notice of such person's designation. ...

31 CFR 588.302 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 588.302 Section 588... Definitions § 588.302 Effective date. The term effective date refers to the effective date of the applicable... are blocked pursuant to § 588.201(a)(2), the earlier of the date of actual or constructive notice that...

26 CFR 1.9001-3 - Basis adjustments for taxable years between changeover date and 1956 adjustment date.

Code of Federal Regulations, 2010 CFR

2010-04-01

... changeover date and 1956 adjustment date. 1.9001-3 Section 1.9001-3 Internal Revenue INTERNAL REVENUE SERVICE....9001-3 Basis adjustments for taxable years between changeover date and 1956 adjustment date. (a) In... before the taxpayer's 1956 adjustment date. This adjusted basis shall be used for all purposes of the...

A NEW LOG EVALUATION METHOD TO APPRAISE MESAVERDE RE-COMPLETION OPPORTUNITIES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Albert Greer

2003-09-11

Artificial intelligence tools, fuzzy logic and neural networks were used to evaluate the potential of the behind pipe Mesaverde formation in BMG's Mancos formation wells. A fractal geostatistical mapping algorithm was also used to predict Mesaverde production. Additionally, a conventional geological study was conducted. To date one Mesaverde completion has been performed. The Janet No.3 Mesaverde completion was non-economic. Both the AI method and the geostatistical methods predicted the failure of the Janet No.3. The Gavilan No.1 in the Mesaverde was completed during the course of the study and was an extremely good well. This well was not included inmore » the statistical dataset. The AI method predicted very good production while the fractal map predicted a poor producer.« less

Violence in Adolescent Dating Relationships

ERIC Educational Resources Information Center

Jouriles, Ernest N.; Platt, Cora; McDonald, Renee

2009-01-01

Beginning with a definition of dating and dating violence among adolescents, this article explores the factors which impact such violence. It concludes with a review of two school-based prevention/intervention programs (Safe Dates and The Youth Relationships Project). (Contains 1 table.)

Radiocarbon Dating, Memories, and Hopes

DOE R&D Accomplishments Database

Libby, W. F.

1972-10-01

The history of radiocarbon dating from 1939 to the present is reviewed. The basic principles of radiocarbon dating are that cosmic rays make living things radioactive with {sup 14}C to a certain level fixed by the environment and that at death the intake of food stops so no replenishment of the {sup 14}C steadily lost by the immutable decay occurs. Therefore measurement of the degree of decay gives the time lapse since death, i.e., the radiocarbon age. The equipment developed and experiments performed to measure the specific activity of specimens to be dated are described. The results obtained by world-wide experimenters are discussed. These showed that on simultaneity radiocarbon dating is apparently reliable but that absolute dates may be incorrect by as much as 600 to 700 y. The value of radiocarbon dating to archaeologists, geologists, climatologists, and historians is stressed. (LCL)

Enhancing Dating Attitudes through Peer Education as a Date Rape Prevention Strategy.

ERIC Educational Resources Information Center

Holcomb, Derek R.; Seehafer, Roger W.

1995-01-01

Presents program development and peer education training considerations for programs that attempt to influence healthy attitudes toward dating and preventing date rape. The paper discusses the program's theoretical foundations, goal determination, mixed-gender programs, themes students raise during programs, the consensual sex scenario as a…

Plutonium age dating reloaded

NASA Astrophysics Data System (ADS)

Sturm, Monika; Richter, Stephan; Aregbe, Yetunde; Wellum, Roger; Mayer, Klaus; Prohaska, Thomas

2014-05-01

Although the age determination of plutonium is and has been a pillar of nuclear forensic investigations for many years, additional research in the field of plutonium age dating is still needed and leads to new insights as the present work shows: Plutonium is commonly dated with the help of the 241Pu/241Am chronometer using gamma spectrometry; in fewer cases the 240Pu/236U chronometer has been used. The age dating results of the 239Pu/235U chronometer and the 238Pu/234U chronometer are scarcely applied in addition to the 240Pu/236U chronometer, although their results can be obtained simultaneously from the same mass spectrometric experiments as the age dating result of latter. The reliability of the result can be tested when the results of different chronometers are compared. The 242Pu/238U chronometer is normally not evaluated at all due to its sensitivity to contamination with natural uranium. This apparent 'weakness' that renders the age dating results of the 242Pu/238U chronometer almost useless for nuclear forensic investigations, however turns out to be an advantage looked at from another perspective: the 242Pu/238U chronometer can be utilized as an indicator for uranium contamination of plutonium samples and even help to identify the nature of this contamination. To illustrate this the age dating results of all four Pu/U clocks mentioned above are discussed for one plutonium sample (NBS 946) that shows no signs of uranium contamination and for three additional plutonium samples. In case the 242Pu/238U chronometer results in an older 'age' than the other Pu/U chronometers, contamination with either a small amount of enriched or with natural or depleted uranium is for example possible. If the age dating result of the 239Pu/235U chronometer is also influenced the nature of the contamination can be identified; enriched uranium is in this latter case a likely cause for the missmatch of the age dating results of the Pu/U chronometers.

26 CFR 1.338-6 - Allocation of ADSP and AGUB among target assets.

Code of Federal Regulations, 2010 CFR

2010-04-01

... allocated among Class II acquisition date assets of target in proportion to the fair market values of such... 26 Internal Revenue 4 2010-04-01 2010-04-01 false Allocation of ADSP and AGUB among target assets... among target assets. (a) Scope—(1) In general. This section prescribes rules for allocating ADSP and...

Chronic and Acute Relational Risk Factors for Dating Aggression in Adolescence and Young Adulthood.

PubMed

Collibee, Charlene; Furman, Wyndol

2016-04-01

Dating aggression is a prevalent and costly public health concern. Using a relational risk framework, this study examined acute and chronic relational risk factors (negative interactions, jealousy, support, and relationship satisfaction) and their effects on physical and psychological dating aggression. The study also examined the interaction between chronic and acute risk, allowing us to assess how changes in acute risk have differing effects depending on whether the individual is typically at higher chronic risk. A sample of 200 youth (100 female) completed seven waves of data, which spanned 9 years from middle adolescence to young adulthood (M age at Wave 1 = 15.83). Using hierarchical linear modeling, analyses revealed both acute (within-person) and chronic (between-person) levels in jealousy, negative interactions, and relationship satisfaction, were associated with physical and psychological dating aggression. Significant interactions between chronic and acute risk emerged in predicting physical aggression for negative interactions, jealousy, and relationship satisfaction such that those with higher levels of chronic risk are more vulnerable to increases in acute risk. These interactions between chronic and acute risk indicate that risk is not static, and dating aggression is particularly likely to occur at certain times for youth at high risk for dating aggression. Such periods of increased risk may provide opportunities for interventions to be particularly effective in preventing dating aggression or its consequences. Taken together, these findings provide support for the role of relational risk factors for dating aggression. They also underscore the importance of considering risk dynamically.

46 CFR 272.44 - Dates.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Dates. 272.44 Section 272.44 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS AFFECTING SUBSIDIZED VESSELS AND OPERATORS REQUIREMENTS... Examination, Audit, Review and Appeal Procedures § 272.44 Dates. The dates noted on the letters or...

46 CFR 272.44 - Dates.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 8 2011-10-01 2011-10-01 false Dates. 272.44 Section 272.44 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS AFFECTING SUBSIDIZED VESSELS AND OPERATORS REQUIREMENTS... Examination, Audit, Review and Appeal Procedures § 272.44 Dates. The dates noted on the letters or...

Direct dating of human fossils.

PubMed

Grün, Rainer

2006-01-01

The methods that can be used for the direct dating of human remains comprise of radiocarbon, U-series, electron spin resonance (ESR), and amino acid racemization (AAR). This review gives an introduction to these methods in the context of dating human bones and teeth. Recent advances in ultrafiltration techniques have expanded the dating range of radiocarbon. It now seems feasible to reliably date bones up to 55,000 years. New developments in laser ablation mass spectrometry permit the in situ analysis of U-series isotopes, thus providing a rapid and virtually non-destructive dating method back to about 300,000 years. This is of particular importance when used in conjunction with non-destructive ESR analysis. New approaches in AAR analysis may lead to a renaissance of this method. The potential and present limitations of these direct dating techniques are discussed for sites relevant to the reconstruction of modern human evolution, including Florisbad, Border Cave, Tabun, Skhul, Qafzeh, Vindija, Banyoles, and Lake Mungo. (c) 2006 Wiley-Liss, Inc.

Metabolome based volatiles profiling in 13 date palm fruit varieties from Egypt via SPME GC-MS and chemometrics.

PubMed

Khalil, Mohammed N A; Fekry, Mostafa I; Farag, Mohamed A

2017-02-15

Dates (Phoenix dactylifera L.) are distributed worldwide as major food complement providing a source of sugars and dietary fiber as well as macro- and micronutrients. Although phytochemical analyses of date fruit non-volatile metabolites have been reported, much less is known about the aroma given off by the fruit, which is critical for dissecting sensory properties and quality traits. Volatile constituents from 13 date varieties grown in Egypt were profiled using SPME-GCMS coupled to multivariate data analysis to explore date fruit aroma composition and investigate potential future uses by food industry. A total of 89 volatiles were identified where lipid-derived volatiles and phenylpropanoid derivatives were the major components of date fruit aroma. Multivariate data analyses revealed that 2,3-butanediol, hexanal, hexanol and cinnamaldehyde contributed the most to classification of different varieties. This study provides the most complete map of volatiles in Egyptian date fruit, with Siwi and Sheshi varieties exhibiting the most distinct aroma among studied date varieties. Copyright © 2016 Elsevier Ltd. All rights reserved.

Socio-economic characterisation of date palm (Phoenix dactylifera L.) growers and date value chains in Pakistan.

PubMed

Fatima, Ghayoor; Khan, Iqrar Ahmad; Buerkert, Andreas

2016-01-01

Increasing food production to feed its rapidly growing population is a major policy goal of Pakistan. The production of traditional staples such as rice (Oryza sativa L.) and bread wheat (Triticum aestivum L.) has been intensified in many regions, but not in remote, drought-ridden areas. In these arid, marginal environments dates and their by-products are an option to complement staples given their high nutritive value and storability. To fill knowledge gaps about the role of date palm in the household (HH) income of rural communities and the structure of date value chains, this project studied date palm production across six districts in four provinces of Pakistan. During 2012-2013 a total of 170 HHs were interviewed with a structured questionnaire using a snowball sampling approach. The results showed that most of the HH were headed by males (99 %) who were married (74 %) and often illiterate (40 %). Agriculture was the main occupation of date palm growers (56 %), while a few coupled agricultural activities with business (17 %) or extra-farm employment opportunities (government 9 %; private sector 8 %). Date sales contributed >50 % to the total income of 39 % of HH and 90-100 % to 24 % of HH. Overall farmers grew a total of 39 date palm cultivars and cultivated an average of 409 ± 559 mature date palms. The majority of the respondents sold dates to commission agents (35 %), contractors (22 %) and wholesalers (21 %), while 28 % of HH cultivated date palms only for self-consumption. Date palm growers had only limited knowledge about high quality date cultivars, optimized farm management and about effective post-harvest conservation. Changes in extension and marketing efforts are needed to allow farmers to better exploit value chains in date thereby reaping higher benefits from improved market access to secure their often marginal income.

76 FR 75907 - Notice of Inventory Completion: Minnesota Indian Affairs Council, Bemidji, MN

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-05

...''). History and Description of the Remains At an unknown date, human remains representing, at minimum, two.... SUMMARY: The Minnesota Indian Affairs Council has completed an inventory of human remains and associated... tribe that believes itself to be culturally affiliated with the human remains may contact the Minnesota...

7 CFR 1000.90 - Dates.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 9 2010-01-01 2009-01-01 true Dates. 1000.90 Section 1000.90 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and... Miscellaneous Provisions § 1000.90 Dates. If a date required for a payment contained in a Federal milk order...

7 CFR 1000.90 - Dates.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 9 2011-01-01 2011-01-01 false Dates. 1000.90 Section 1000.90 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and... Miscellaneous Provisions § 1000.90 Dates. If a date required for a payment contained in a Federal milk order...

A combined method for DNA analysis and radiocarbon dating from a single sample.

PubMed

Korlević, Petra; Talamo, Sahra; Meyer, Matthias

2018-03-07

Current protocols for ancient DNA and radiocarbon analysis of ancient bones and teeth call for multiple destructive samplings of a given specimen, thereby increasing the extent of undesirable damage to precious archaeological material. Here we present a method that makes it possible to obtain both ancient DNA sequences and radiocarbon dates from the same sample material. This is achieved by releasing DNA from the bone matrix through incubation with either EDTA or phosphate buffer prior to complete demineralization and collagen extraction utilizing the acid-base-acid-gelatinization and ultrafiltration procedure established in most radiocarbon dating laboratories. Using a set of 12 bones of different ages and preservation conditions we demonstrate that on average 89% of the DNA can be released from sample powder with minimal, or 38% without any, detectable collagen loss. We also detect no skews in radiocarbon dates compared to untreated samples. Given the different material demands for radiocarbon dating (500 mg of bone/dentine) and DNA analysis (10-100 mg), combined DNA and collagen extraction not only streamlines the sampling process but also drastically increases the amount of DNA that can be recovered from limited sample material.

Dyadic Dynamics in Young Couples Reporting Dating Violence: An Actor-Partner interdependence model

PubMed Central

Paradis, Alison; Hébert, Martine; Fernet, Mylène

2016-01-01

This study uses a combination of observational methods and dyadic data analysis to understand how boyfriends’ and girlfriends’ perpetration of dating violence may shape their own and their partners’ problem-solving communication behaviors. A sample of 39 young heterosexual couples aged between 15 and 20 years (mean age 17.8 years) completed a set of questionnaires and were observed during a 45 minute dyadic interaction, which was coded using the Interactional Dimension Coding System (IDCS). Results suggest that, neither boyfriends nor girlfriends own perpetration of dating violence was related to their display of positive and negative communication behaviors. However, estimates revealed significant partner effects, suggesting that negative communication behaviors displayed by girls and boys and positive communication behavior displayed by girls were associated to their partner’s dating violence but not to their own. Such results confirm the need to shift our focus from an individual perspective to examining dyadic influences and processes involved in the couple system and the bi-directionality of violent relationships. PMID:25969443

Double the dates and go for Bayes - Impacts of model choice, dating density and quality on chronologies

NASA Astrophysics Data System (ADS)

Blaauw, Maarten; Christen, J. Andrés; Bennett, K. D.; Reimer, Paula J.

2018-05-01

Reliable chronologies are essential for most Quaternary studies, but little is known about how age-depth model choice, as well as dating density and quality, affect the precision and accuracy of chronologies. A meta-analysis suggests that most existing late-Quaternary studies contain fewer than one date per millennium, and provide millennial-scale precision at best. We use existing and simulated sediment cores to estimate what dating density and quality are required to obtain accurate chronologies at a desired precision. For many sites, a doubling in dating density would significantly improve chronologies and thus their value for reconstructing and interpreting past environmental changes. Commonly used classical age-depth models stop becoming more precise after a minimum dating density is reached, but the precision of Bayesian age-depth models which take advantage of chronological ordering continues to improve with more dates. Our simulations show that classical age-depth models severely underestimate uncertainty and are inaccurate at low dating densities, and also perform poorly at high dating densities. On the other hand, Bayesian age-depth models provide more realistic precision estimates, including at low to average dating densities, and are much more robust against dating scatter and outliers. Indeed, Bayesian age-depth models outperform classical ones at all tested dating densities, qualities and time-scales. We recommend that chronologies should be produced using Bayesian age-depth models taking into account chronological ordering and based on a minimum of 2 dates per millennium.

The scientific dating of standing buildings.

PubMed

Alcock, Nathaniel W

2017-11-17

The techniques of dendrochronology (tree-ring dating) and radiocarbon (14C) dating are described, as they are applied to historic buildings. Both rely on determining the felling dates of the trees used in their construction. For dendrochronology, the construction of master chronologies and the matching of individual ring-width sequences to them is described and, for radiocarbon dating, the use of tree-ring results in calibration. Results of dating are discussed, ranging from the cathedrals of Peterborough and Beauvais and the development of crown-post roof structures, to the dating and identification of standing medieval peasant houses, particularly those built using cruck construction.

Can Young Adults Accurately Report Sexual Partnership Dates? Factors Associated with Inter-partner and Dyad Agreement

PubMed Central

Sanchez, Diana Maria; Schoenbach, Victor J.; Harvey, S. Marie; Warren, Jocelyn T.; Poole, Charles; Leone, Peter A.; Adimora, Adaora A.; Agnew, Christopher R.

2016-01-01

Background Sexual partnership dates are critical to STI/HIV research and control programs, though validity is limited by inaccurate recall and reporting. Methods We examined data from 302 heterosexual adults (151 index-partner dyads) to assess reliability of reporting. Dates of first and last sex were collected through individual interviews and joint dyad questionnaires which partners completed together. We compared index- and partner-reported dates to estimate inter-partner agreement (IPA). We used log-linear regression to model associations between inter-partner differences and partnership characteristics. To assess validity, we compared individually-reported dates to those from joint dyad questionnaires. Results Most partnerships (66.2%) were ≤2 years in duration and many (36.2%) were non-monogamous. IPA to within 1-, 30-, and 365-days was, respectively, 5.6%, 43.1% and 81.3% for first sex; and 32.9%, 94.5%, and 100.0% for last sex. In adjusted models: longer relationship duration was associated with disagreement on first sex dates; partnership non-monogamy was associated with disagreement on dates of first and last sex. Within dyads, several participant characteristics were associated with reporting dates closer to joint dyad responses [e.g., for first sex date, female gender (54.7%), having fewer sex partners (58.5%), and greater relationship commitment (57.3%)]. However, percent agreement to within 30, 60, and 90 days was similar for all groups for both first and last sex dates. Conclusions Agreement was high on date of last sex but only moderate on date of first sex. Methods to increase accuracy of reporting of dates of sex may improve STI research. PMID:27100770

38 CFR 21.9635 - Discontinuance dates.

Code of Federal Regulations, 2013 CFR

2013-07-01

... effective the last date of attendance; and (ii) Independent study or distance learning effective on the... learning, VA will terminate educational assistance effective the date the last lesson was serviced... Discontinuance dates. The effective date of a reduction or discontinuance of educational assistance will be as...

Dating Violence and Sexual Risk Behaviors in a Sample of At-Risk Israeli Youth

ERIC Educational Resources Information Center

Schiff, Miriam; Zeira, Anat

2005-01-01

Objective: This exploratory study examines the reported dating violence and its association with sexual risk behavior among Israeli adolescents, who are at risk for dropping out of school. Methodology: A convenience sample of 105 at-risk youth (51 boys and 54 girls) completed self-administered anonymous, questionnaires in small same-gender groups.…

Mind-reading accuracy in intimate relationships: assessing the roles of the relationship, the target, and the judge.

PubMed

Thomas, Geoff; Fletcher, Garth J O

2003-12-01

Using a video-review procedure, multiple perceivers carried out mind-reading tasks of multiple targets at different levels of acquaintanceship (50 dating couples, friends of the dating partners, and strangers). As predicted, the authors found that mind-reading accuracy was (a). higher as a function of increased acquaintanceship, (b). relatively unaffected by target effects, (c). influenced by individual differences in perceivers' ability, and (d). higher for female than male perceivers. In addition, superior mind-reading accuracy (for dating couples and friends) was related to higher relationship satisfaction, closeness, and more prior disclosure about the problems discussed, but only under moderating conditions related to sex and relationship length. The authors conclude that the nature of the relationship between the perceiver and the target occupies a pivotal role in determining mind-reading accuracy.

Peer involvement in adolescent dating violence.

PubMed

Stephenson, Pam S; Martsolf, Donna; Draucker, Claire Burke

2013-06-01

This study investigated the ways in which peers are involved in adolescent dating violence. Eighty-eight young adults aged 18-21 were interviewed and asked to reflect on aggressive dating relationships they experienced as teens. The researchers used grounded theory to analyze the data. Findings showed that male and female peers were involved in adolescent dating violence in unique ways. Male peers were involved in dating violence by participating in the aggression, agitating the aggression, being the competition, trivializing the aggression, and keeping tabs on the recipient. Female peers were involved in dating violence by deserting the recipient, cheating with the boyfriend, being the audience, needling the male dating partner, and helping the recipient. Male and female peers were involved similarly in adolescent dating violence by confronting the partner. School nurses working with adolescents are uniquely positioned to approach adolescents about dating violence. Interventions aimed at promoting discussions with adolescents are discussed.

25. Photocopy of aerial photograph dated May 1930; J. E. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

25. Photocopy of aerial photograph dated May 1930; J. E. Quigley, Photographer; original filed as MR2.9/SP8/p355 in Audio-visual Collection of Minnesota Historical Society, St. Paul; SHOWS RECENTLY COMPLETED NORTHWEST HANGAR AND ADMINISTRATION BUILDING I N UPPER LEFT (THREE-QUARTER VIEW OF WEST SIDE AND SOUTH FRONT); ALSO SHOWS THE SIMILARLY DESIGNED MUNICIPAL HANGAR UNDER CONSTRUCTION IN FOREGROUND; LOOKING NORTHEAST - Northwest Airways Hangar & Administration Building, 590 Bayfield Street, St. Paul Downtown Airport (Holman), Saint Paul, Ramsey County, MN

Gates Fund Creates Plan for College Completion

ERIC Educational Resources Information Center

Gose, Ben

2008-01-01

The Bill & Melinda Gates Foundation plans to spend several hundred million dollars over the next five years to double the number of low-income young people who complete a college degree or certificate program by age 26. Foundation officials described the ambitious plan to an exclusive group of education leaders, citing 2025 as a target goal. If…

31 CFR 598.302 - Effective date.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Effective date. 598.302 Section 598.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... Definitions § 598.302 Effective date. The term effective date refers to the effective date of the applicable...

31 CFR 598.302 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 598.302 Section 598.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... Definitions § 598.302 Effective date. The term effective date refers to the effective date of the applicable...

31 CFR 598.302 - Effective date.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Effective date. 598.302 Section 598.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... Definitions § 598.302 Effective date. The term effective date refers to the effective date of the applicable...

31 CFR 598.302 - Effective date.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Effective date. 598.302 Section 598.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... Definitions § 598.302 Effective date. The term effective date refers to the effective date of the applicable...

31 CFR 598.302 - Effective date.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Effective date. 598.302 Section 598.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... Definitions § 598.302 Effective date. The term effective date refers to the effective date of the applicable...

31 CFR 510.302 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 510.302 Section 510.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... § 510.302 Effective date. The term effective date refers to the effective date of the applicable...

31 CFR 510.302 - Effective date.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Effective date. 510.302 Section 510.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... § 510.302 Effective date. The term effective date refers to the effective date of the applicable...

31 CFR 510.302 - Effective date.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Effective date. 510.302 Section 510.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... § 510.302 Effective date. The term effective date refers to the effective date of the applicable...

31 CFR 540.302 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 540.302 Section 540.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... REGULATIONS General Definitions § 540.302 Effective date. The term effective date refers to the effective date...

31 CFR 538.302 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 538.302 Section 538.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... § 538.302 Effective date. The term effective date refers to the effective date of the applicable...

31 CFR 592.302 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 592.302 Section 592.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... § 592.302 Effective date. The term effective date refers to the effective date of the applicable...

31 CFR 596.302 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 596.302 Section 596.302 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... General Definitions § 596.302 Effective date. The term effective date refers to the effective date of the...

7 CFR 987.45 - Withholding restricted dates.

Code of Federal Regulations, 2014 CFR

2014-01-01

... restricted dates. (a) Whenever free and restricted percentages for any variety of dates have been established... having dates of such variety certified for handling as free dates (including those for further processing that are to be handled as free dates), withhold from handling a quantity of marketable dates of such...

Radiocarbon Dating the Anthropocene

NASA Astrophysics Data System (ADS)

Chaput, M. A.; Gajewski, K. J.

2015-12-01

The Anthropocene has no agreed start date since current suggestions for its beginning range from Pre-Industrial times to the Industrial Revolution, and from the mid-twentieth century to the future. To set the boundary of the Anthropocene in geological time, we must first understand when, how and to what extent humans began altering the Earth system. One aspect of this involves reconstructing the effects of prehistoric human activity on the physical landscape. However, for global reconstructions of land use and land cover change to be more accurately interpreted in the context of human interaction with the landscape, large-scale spatio-temporal demographic changes in prehistoric populations must be known. Estimates of the relative number of prehistoric humans in different regions of the world and at different moments in time are needed. To this end, we analyze a dataset of radiocarbon dates from the Canadian Archaeological Radiocarbon Database (CARD), the Palaeolithic Database of Europe and the AustArch Database of Australia, as well as published dates from South America. This is the first time such a large quantity of dates (approximately 60,000) has been mapped and studied at a global scale. Initial results from the analysis of temporal frequency distributions of calibrated radiocarbon dates, assumed to be proportional to population density, will be discussed. The utility of radiocarbon dates in studies of the Anthropocene will be evaluated and potential links between population density and changes in atmospheric greenhouse gas concentrations, climate, migration patterning and fire frequency coincidence will be considered.

24 CFR 1710.21 - Effective dates.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Effective dates. 1710.21 Section... Effective dates. (a) General. The effective date of an initial, consolidated or amended Statement of Record... developer in writing prior to such 30th day that: (1) The effective date has been suspended in accordance...

A complete representation of uncertainties in layer-counted paleoclimatic archives

NASA Astrophysics Data System (ADS)

Boers, Niklas; Goswami, Bedartha; Ghil, Michael

2017-09-01

Accurate time series representation of paleoclimatic proxy records is challenging because such records involve dating errors in addition to proxy measurement errors. Rigorous attention is rarely given to age uncertainties in paleoclimatic research, although the latter can severely bias the results of proxy record analysis. Here, we introduce a Bayesian approach to represent layer-counted proxy records - such as ice cores, sediments, corals, or tree rings - as sequences of probability distributions on absolute, error-free time axes. The method accounts for both proxy measurement errors and uncertainties arising from layer-counting-based dating of the records. An application to oxygen isotope ratios from the North Greenland Ice Core Project (NGRIP) record reveals that the counting errors, although seemingly small, lead to substantial uncertainties in the final representation of the oxygen isotope ratios. In particular, for the older parts of the NGRIP record, our results show that the total uncertainty originating from dating errors has been seriously underestimated. Our method is next applied to deriving the overall uncertainties of the Suigetsu radiocarbon comparison curve, which was recently obtained from varved sediment cores at Lake Suigetsu, Japan. This curve provides the only terrestrial radiocarbon comparison for the time interval 12.5-52.8 kyr BP. The uncertainties derived here can be readily employed to obtain complete error estimates for arbitrary radiometrically dated proxy records of this recent part of the last glacial interval.

Targeted neonatal echocardiography services: need for standardized training and quality assurance.

PubMed

Finan, Emer; Sehgal, Arvind; Khuffash, Afif El; McNamara, Patrick J

2014-10-01

Targeted neonatal echocardiography refers to a focused assessment of myocardial performance and hemodynamics directed by a specific clinical question. It has become the standard of care in many parts of the world, but practice is variable, and there has been a lack of standardized training and evaluation to date. Targeted neonatal echocardiography was first introduced to Canada in 2006. The purpose of this study was to examine the characteristics of targeted neonatal echocardiography practice and training methods in Canadian neonatal intensive care units (NICUs). A total of 142 Canadian neonatologists were invited to participate in an online survey, which was conducted in September 2010. The survey consisted of questions related to the availability of targeted neonatal echocardiography, clinical indications, benefits and risks, and training methods. The overall survey response rate was 65%. Forty-eight respondents (34%) indicated that targeted neonatal echocardiography was available in their units, and the program was introduced within the preceding 1 to 5 years. In centers where it was unavailable, lack of on-site echocardiography expertise was cited as the major barrier to implementation. The most common indications for targeted neonatal echocardiography included evaluation of a hemodynamically significant ductus arteriosus, systemic or pulmonary blood flow, and response to cardiovascular treatments. Only 27% of respondents, working in centers where targeted neonatal echocardiography existed, actually performed the studies themselves; most individuals completed 11 to 20 studies per month. Almost half of the respondents said that training was available in their institutions, but methods of training and evaluation were inconsistent. Eighty-seven percent of respondents reported no formalized process for assessment of ongoing competency after the initial training period. Targeted neonatal echocardiography is becoming more widely available and is gaining acceptance in

40 CFR 469.21 - Compliance dates.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Compliance dates. 469.21 Section 469....21 Compliance dates. The compliance date for the BAT fluoride limitation is as soon as possible as determined by the permit writer but in no event later than November 8, 1985. The compliance date for PSES for...

40 CFR 469.21 - Compliance dates.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 30 2011-07-01 2011-07-01 false Compliance dates. 469.21 Section 469....21 Compliance dates. The compliance date for the BAT fluoride limitation is as soon as possible as determined by the permit writer but in no event later than November 8, 1985. The compliance date for PSES for...

31 CFR 539.302 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 539.302 Section 539... General Definitions § 539.302 Effective date. The term effective date means the “effective date” specified... foreign person. This date is listed after the name of each designated foreign person in appendix I to this...

24 CFR 35.105 - Effective dates.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Effective dates. 35.105 Section 35... Requirements and Definitions for All Programs. § 35.105 Effective dates. The effective date for subparts B through R of this part is September 15, 2000, except that the effective date for prohibited methods of...

Partner Characteristics and the Effectiveness of Practice Dating Procedures in the Treatment of Minimal Dating.

ERIC Educational Resources Information Center

Perl, Joseph; And Others

A treatment program was instituted to reduce dating anxiety in infrequent daters. A sample of 85 extremely anxious and inhibited college undergraduates of both sexes volunteered for the program. Subjects were randomly assigned to one of three practice dating groups and two control groups. In one practice dating group, each non-dater was paired…

Chronic and Acute Relational Risk Factors for Dating Aggression in Adolescence and Young Adulthood

PubMed Central

Furman, Wyndol

2016-01-01

Dating aggression is a prevalent and costly public health concern. Using a relational risk framework, this study examined acute and chronic relational risk factors (negative interactions, jealousy, support, & relationship satisfaction) and their effects on physical and psychological dating aggression. The study also examined the interaction between chronic and acute risk, allowing us to assess how changes in acute risk have differing effects depending on whether the individual is typically at higher chronic risk. A sample of 200 youth (100 female) completed seven waves of data, which spanned nine years from middle adolescence to young adulthood (M age at Wave 1 = 15.83). Using hierarchical linear modeling, analyses revealed both acute (within-person) and chronic (between-person) levels in jealousy, negative interactions, and relationship satisfaction, were associated with physical and psychological dating aggression. Significant interactions between chronic and acute risk emerged in predicting physical aggression for negative interactions, jealousy, and relationship satisfaction such that those with higher levels of chronic risk are more vulnerable to increases in acute risk. These interactions between chronic and acute risk indicate that risk is not static, and dating aggression is particularly likely to occur at certain times for youth at high risk for dating aggression. Such periods of increased risk may provide opportunities for interventions to be particularly effective in preventing dating aggression or its consequences. Taken together, these findings provide support for the role of relational risk factors for dating aggression. They also underscore the importance of considering risk dynamically. PMID:26832727

Targeted Therapies for Autosomal Dominant Polycystic Kidney Disease.

PubMed

Stayner, Cherie; Brooke, Darby G; Bates, Michael; Eccles, Michael R

2018-05-07

Autosomal dominant polycystic kidney disease (ADPKD) is the most common life-threatening genetic disease in humans, affecting approximately 1 in 500 people. ADPKD is characterized by cyst growth in the kidney leading to progressive parenchymal damage and is the underlying pathology in approximately 10% of patients requiring hemodialysis or transplantation for end-stage kidney disease. The two proteins that are mutated in ADPKD, polycystin-1 and polycystin-2, form a complex located on the primary cilium and the plasma membrane to facilitate calcium ion release in the cell. There is currently no Food and Drug Administration (FDA)-approved therapy to cure or slow the progression of the disease. Rodent ADPKD models do not completely mimic the human disease, and therefore preclinical results have not always successfully translated to the clinic. Moreover, the toxicity of many of these potential therapies has led to patient withdrawals from clinical trials. Here, we review compounds in a clinical trial for treating ADPKD, and we examine the feasibility of using a kidney-targeted approach, with potential for broadening the therapeutic window, decreasing treatment-associated toxicity and increasing the efficacy of agents that have demonstrated activity in animal models. We make recommendations for integrating kidney-targeted therapies with current treatment regimes, to achieve a combined approach to treating ADPKD. Many compounds are currently in clinical trial for ADPKD, yet to date, none are FDA-approved for treating this disease. Patients could benefit from efficacious pharmacotherapy, especially if it can be kidney-targeted, and intensive efforts continue to be focused on this goal. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Radiometric Dating in Geology.

ERIC Educational Resources Information Center

Pankhurst, R. J.

1980-01-01

Described are several aspects and methods of quantitatively measuring geologic time using a constant-rate natural process of radioactive decay. Topics include half lives and decay constants, radiogenic growth, potassium-argon dating, rubidium-strontium dating, and the role of geochronology in support of geological exploration. (DS)

Choosing a calving date

USDA-ARS?s Scientific Manuscript database

Calving date affects cost and timing of production events. Due to the polyestrous nature of beef females, producers can choose a calving date that fits their production system and geographic region. Any time an entire production system is considered, decision making becomes complex. Any calving syst...

31 CFR 542.302 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 542.302 Section 542....302 Effective date. With respect to a person whose property or interests in property are blocked pursuant to a designation under § 542.201(a), the effective date is the earlier of the date on which either...

31 CFR 560.301 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Effective date. 560.301 Section 560... § 560.301 Effective date. The effective date of the prohibitions and directives contained in subpart B of this part is 12:01 a.m., Eastern Daylight Time, August 20, 1997. For the effective date of pre...

18 CFR 11.7 - Effective date.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Effective date. 11.7... Dams § 11.7 Effective date. All annual charges imposed under this subpart will be computed beginning on the effective date of the license unless some other date is fixed in the license. [51 FR 24318, July 3...

Endocannabinoids as a Target for the Treatment of Traumatic Brain Injury

DTIC Science & Technology

2012-11-01

DATES COVERED 4 October 2011- 3 October 2012 4. TITLE AND SUBTITLE Endocannabinoids as a Target for the Treatment of Traumatic Brain Injury 5a...interventions aimed at modulation of the endocannabinoid (EC) system targeting degradation of 20arachidonoyl glycerlol (2- AG) and N-arachidonoyl...percussion, traumatic brain injury, blood brain barrier, neuroinflammination, neurological dysfunction, endocannabinoids . 16. SECURITY CLASSIFICATION

Dating of Modern Human Evolution

NASA Astrophysics Data System (ADS)

Grun, R.

Dating studies on palaoeanthropological sites is usually carried out on material associ- ated with the human remains, such as the sediment, charcoal or other fauna rather than the human specimen itself. The reason lies in the fact that most dating techniques are destructive and because the hominid remains are too rare to be sacrificed for dating. This indirect dating approach is in many cases not satisfactory, because: (i) the human remains are often buried into the sediments and the association with other materials is uncertain (e.g. Skhul, Qafzeh, etc.); (ii) faunal remains or minerals from the sediment are re-worked from older deposits (see e.g. present discussion of the age of the Homo erectus remains in Indonesia; (iii) the hominid fossils were discovered at a time when no careful excavations were carried out and it is impossible to correlate the specimen with other datable material (which applies tonearly 90% of all palaeoanthropological specimens). For example, the hominid burial site of Qafzeh in Israel has been dated by several independent dating laboratories with a multitude of methods. However, the data are still not accepted by some because the dating has not been carried out on the hominid specimen. Until recently, hominid fossils could only be dated by radiocarbon. This method reaches back to about 40,000 years. As a consequence, all the older fossils could not be analysed and many important questions in our understanding of human evolution could not be addressed. Human remains are scarce and extremely valuable, therefore any sort of destruction has to be kept to an absolute minimum. This is of particular importance in Australia where any human fossils are sacred. Thus, for the analysis of hominid material it was necessary to develop a more or less non-destructive techniques. This has been ac- complished in recent years by the application of ESR dating of tooth enamel and a combination of gamma spectrometric and TIMS U-series dating of bones. The exam

Case studies from Oman for coiled tubing deployed completion techniques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taylor, R.W.; Conrad, B.

1996-09-01

Although the use of ultra-large coiled tubing to complete wells is relatively new, it is gaining widespread industry application. This paper will detail the equipment necessary to perform an operation of this type and will present information from several case studies in Oman in which an operator has successfully deployed completion equipment on 3-1/2-inch-OD coiled tubing. In addition to a discussion of the equipment required to perform the necessary operations, the trial parameters that were established by this operator will be given. The information presented has been selected to allow an initial evaluation to be made of coiled tubing completionsmore » in general and will help to determine whether this method can prove to be less expensive than traditional rig-based completions. The topics presented have been chosen to provide the reader with a thorough understanding of the techniques and preparation needed to execute a coiled tubing completion. The summary of experiences will conclude that this innovative completion technique can be a viable method for completing wells. Although long-term advantages regarding production and well maintenance cannot yet be determined, the operator`s experiences to date have confirmed his initial belief that use of coiled tubing in ultra-large continuous-pipe applications can be cost effective.« less

Exposure to family violence and attachment styles as predictors of dating violence perpetration among men and women: a mediational model.

PubMed

Lee, Mary; Reese-Weber, Marla; Kahn, Jeffrey H

2014-01-01

This study examined a multiple mediator model explaining how sibling perpetration and one's attachment style mediate the relation between parent-to-child victimization and dating violence perpetration. A sample of undergraduate students (n = 392 women, n = 89 men) completed measures of the aforementioned variables on an Internet survey. For men, path analyses found no mediation; parent-to-child victimization had a direct association with dating violence perpetration, no association was found between sibling perpetration and dating violence perpetration, and attachment anxiety, but not attachment avoidance, was positively associated with dating violence perpetration for men. For women, the hypothesized mediation model was supported; parent-to-child victimization had a direct association with dating violence perpetration, and sibling perpetration and attachment anxiety served as mediating variables. Attachment avoidance was not associated with dating violence perpetration for women. Implications for future research and clinical practice are discussed.

The effect of family and peer communication on college students' communication with dating partners about HIV and AIDS.

PubMed

Powell, Heather L; Segrin, Chris

2004-01-01

As family and peers are primary socializing agents in the lives of young adults, a social learning based model of communication about HIV/AIDS among dating partners was developed and tested, examining the role of interactions with family and peers in this type of communication. Specifically, the model describes relationships between general communication, communication about sexuality, and communication about HIV/AIDS with parents, peers, and dating partners. Participants were 153 young adult couples who completed measures of their communication practices, as well as their communication with family and peers. Communication practices in the family of origin appear to influence both general communication and communication about HIV/AIDS with dating partners. Communication practices with peers influenced general communication, communication about sexuality, and communication about HIV/AIDS with dating partners. Participants and their dating partners exhibited relative agreement about their general communication practices and their communication about HIV/AIDS, but showed less agreement in reports of their communication about sexuality. Implications for understanding the role of family and peer interactions in communication about HIV/AIDS with dating partners are discussed.

Teen dating abuse: recognition and interventions.

PubMed

Freeman, Sally Ann; Rosenbluth, Barri; Cotton, Laura

2013-03-01

Teen dating abuse, also known as teen dating violence, is a significant public health issue. Adolescents with a history of dating abuse may struggle academically and experience increased risk for serious injury or even death. They may engage in risky sexual behavior, substance abuse, and unhealthy dieting and exhibit suicidal behaviors. School nurses may be the first adults that teens confide in when experiencing dating abuse and may lack the knowledge and skills to intervene with teens involved in unhealthy dating relationships. Beginning in 2008, Dell Children s Medical Center in Austin, Texas, partnered with SafePlace (a local nonprofit that serves survivors of sexual and domestic violence) to address dating abuse. This collaboration is part of Start Strong Austin, one of 11 communities nationwide participating in the Start Strong: Building Healthy Teen Relationships Initiative funded by the Robert Wood Johnson Foundation. The Start Strong model employs innovative strategies in education, community engagement, policy change, and social marketing to prevent dating abuse before it starts.

EPA RE-Powering Mapper Completed Installations

EPA Pesticide Factsheets

The U.S. Environmental Protection Agency (EPA) Office of Land and Emergency Management (OLEM) Office of Communications, Partnerships and Analysis (OCPA) initiated the RE-Powering America's Land Initiative to demonstrate the enormous potential that contaminated lands, landfills, and mine sites provide for developing renewable energy in the United States. Using publically available information, RE-Powering maintains a list of completed renewable energy installations on contaminated sites and landfills. To date, the RE-Powering Initiative has identified 179 renewable energy installations on 171 contaminated lands, landfills, and mine sites, with a cumulative installed capacity of just over 1,124 megawatts (MW) and consistent growth in total installations since the inception of the RE-Powering Initiative. This dataset is current as of April 2016.

New High Gain Target Design for a Laser Fusion Power Plant

DTIC Science & Technology

2000-06-07

target with a minimum energy gain, about 100. Demonstration of ignition or low gain is only important for fusion energy if it leads into a target concept...nonlinear saturation of these instabilities. Our approach is to try to avoid them. 4. A Development Path to Fusion Energy The laser and target concept...on the exact date required to develop fusion energy , it would be worthwhile for a power plant development program to provide enough time and funds

Pests of stored dates

USDA-ARS?s Scientific Manuscript database

Dates are a major food crop across a large band of Africa and Eurasia, and to a lesser extent elsewhere. In most of its growing range, dates are threatened with infestation in the field by a complex of pests including nitidulid beetles and pyralid moths of the Subfamily Phycitinae. They are further ...

Radiocarbon Dating of the Human Eye Lens Crystallines Reveal Proteins without Carbon Turnover throughout Life

PubMed Central

Lynnerup, Niels; Kjeldsen, Henrik; Heegaard, Steffen; Jacobsen, Christina; Heinemeier, Jan

2008-01-01

Background Lens crystallines are special proteins in the eye lens. Because the epithelial basement membrane (lens capsule) completely encloses the lens, desquamation of aging cells is impossible, and due to the complete absence of blood vessels or transport of metabolites in this area, there is no subsequent remodelling of these fibers, nor removal of degraded lens fibers. Human tissue ultimately derives its 14C content from the atmospheric carbon dioxide. The 14C content of the lens proteins thus reflects the atmospheric content of 14C when the lens crystallines were formed. Precise radiocarbon dating is made possible by comparing the 14C content of the lens crystallines to the so-called bomb pulse, i.e. a plot of the atmospheric 14C content since the Second World War, when there was a significant increase due to nuclear-bomb testing. Since the change in concentration is significant even on a yearly basis this allows very accurate dating. Methodology/Principal Findings Our results allow us to conclude that the crystalline formation in the lens nucleus almost entirely takes place around the time of birth, with a very small, and decreasing, continuous formation throughout life. The close relationship may be further expressed as a mathematical model, which takes into account the timing of the crystalline formation. Conclusions/Significance Such a life-long permanence of human tissue has hitherto only been described for dental enamel. In confront to dental enamel it must be held in mind that the eye lens is a soft structure, subjected to almost continuous deformation, due to lens accommodation, yet its most important constituent, the lens crystalline, is never subject to turnover or remodelling once formed. The determination of the 14C content of various tissues may be used to assess turnover rates and degree of substitution (for example for brain cell DNA). Potential targets may be nervous tissues in terms of senile or pre-senile degradation, as well as other highly

Maladaptive schemas as mediators of the relationship between previous victimizations in the family and dating violence victimization in adolescents.

PubMed

Calvete, Esther; Gámez-Guadix, Manuel; Fernández-Gonzalez, Liria; Orue, Izaskun; Borrajo, Erika

2018-07-01

This study examined whether exposure to family violence, both in the form of direct victimization and witnessing violence, predicted dating violence victimization in adolescents through maladaptive schemas. A sample of 933 adolescents (445 boys and 488 girls), aged between 13 and 18 (M = 15.10), participated in a three-year longitudinal study. They completed measures of exposure to family violence, maladaptive schemas of disconnection/rejection, and dating violence victimization. The findings indicate that witnessing family violence predicts the increase of dating violence victimization over time, through the mediation of maladaptive schemas in girls, but not in boys. Direct victimization in the family predicts dating violence victimization directly, without the mediation of schemas. In addition, maladaptive schemas contribute to the perpetuation of dating violence victimization over time. These findings provide new opportunities for preventive interventions, as maladaptive schemas can be modified. Copyright © 2018 Elsevier Ltd. All rights reserved.

Dating Violence in Russia

ERIC Educational Resources Information Center

Lysova, A. V.

2007-01-01

The phenomenon of violence in interpersonal relationships has been little studied in Russia, and the phenomenon of violence between dating partners has not been the object of scientific interest at all. The study on which the present article is based was designed to obtain information about the violence in dating among students enrolled in…

Activity targets for nanostructured platinum-group-metal-free catalysts in hydroxide exchange membrane fuel cells.

PubMed

Setzler, Brian P; Zhuang, Zhongbin; Wittkopf, Jarrid A; Yan, Yushan

2016-12-06

Fuel cells are the zero-emission automotive power source that best preserves the advantages of gasoline automobiles: low upfront cost, long driving range and fast refuelling. To make fuel-cell cars a reality, the US Department of Energy has set a fuel cell system cost target of US$30 kW -1 in the long-term, which equates to US$2,400 per vehicle, excluding several major powertrain components (in comparison, a basic, but complete, internal combustion engine system costs approximately US$3,000). To date, most research for automotive applications has focused on proton exchange membrane fuel cells (PEMFCs), because these systems have demonstrated the highest power density. Recently, however, an alternative technology, hydroxide exchange membrane fuel cells (HEMFCs), has gained significant attention, because of the possibility to use stable platinum-group-metal-free catalysts, with inherent, long-term cost advantages. In this Perspective, we discuss the cost profile of PEMFCs and the advantages offered by HEMFCs. In particular, we discuss catalyst development needs for HEMFCs and set catalyst activity targets to achieve performance parity with state-of-the-art automotive PEMFCs. Meeting these targets requires careful optimization of nanostructures to pack high surface areas into a small volume, while maintaining high area-specific activity and favourable pore-transport properties.

Activity targets for nanostructured platinum-group-metal-free catalysts in hydroxide exchange membrane fuel cells

NASA Astrophysics Data System (ADS)

Setzler, Brian P.; Zhuang, Zhongbin; Wittkopf, Jarrid A.; Yan, Yushan

2016-12-01

Fuel cells are the zero-emission automotive power source that best preserves the advantages of gasoline automobiles: low upfront cost, long driving range and fast refuelling. To make fuel-cell cars a reality, the US Department of Energy has set a fuel cell system cost target of US$30 kW-1 in the long-term, which equates to US$2,400 per vehicle, excluding several major powertrain components (in comparison, a basic, but complete, internal combustion engine system costs approximately US$3,000). To date, most research for automotive applications has focused on proton exchange membrane fuel cells (PEMFCs), because these systems have demonstrated the highest power density. Recently, however, an alternative technology, hydroxide exchange membrane fuel cells (HEMFCs), has gained significant attention, because of the possibility to use stable platinum-group-metal-free catalysts, with inherent, long-term cost advantages. In this Perspective, we discuss the cost profile of PEMFCs and the advantages offered by HEMFCs. In particular, we discuss catalyst development needs for HEMFCs and set catalyst activity targets to achieve performance parity with state-of-the-art automotive PEMFCs. Meeting these targets requires careful optimization of nanostructures to pack high surface areas into a small volume, while maintaining high area-specific activity and favourable pore-transport properties.

Peer Group Influences on Adolescent Dating Aggression

ERIC Educational Resources Information Center

Connolly, Jennifer; Friedlander, Laura

2009-01-01

The peer group is a critical social context for dating and romantic relationships. Peer groups provide opportunities to meet potential dating partners and set norms for acceptable dating behaviors. This article explores how peer groups influence dating and dating aggression, as well as how they can be used in prevention efforts. It also reviews…

Shell We Date? ESR Dating Sangamon Interglacial Episode Deposits at Hopwood Farm, IL.

PubMed

Blackwell, Bonnie A B; Kim, Danny M K; Curry, B Brandon; Grimley, David A; Blickstein, Joel I B; Skinner, Anne R

2016-12-01

During the Sangamon Episode, North America occasionally experienced warm climates. At Hopwood Farm, IL, a small kettle lake filled with sediment after the Illinois Episode glaciers retreated from southern Illinois. To date those deposits, 14 mollusc samples newly collected with associated sediment from three depths at Hopwood Farm were dated by standard electron spin resonance (ESR) dating. ESR can date molluscs from ~0.5 ka to >2 Ma in age with 5-10% precision, by comparing the accumulated radiation dose with the total radiation dose rate from the mollusc and its environment. Because all molluscs contained ≤0.6 ppm U, their ages do not depend on the assumed U uptake model. Using five different species, ESR analyses for 14 mollusc subsamples from Hopwood Farm showed that Unit 3, a layer rich in lacustrine molluscs, dates at 102 ± 7 ka to 90 ± 6 ka, which correlates with Marine (Oxygen) Isotope Stage 5c-b. Thus, the period with the highest non-arboreal pollen at Hopwood also correlates with the European Brørup, Dansgaard-Oeschger Event DO 23, a time period when climates were cooling and drying somewhat over the same period. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

40 CFR 63.403 - Compliance dates.

Code of Federal Regulations, 2010 CFR

2010-07-01

... compliance date shall be 18 months after September 8, 1994. (b) For new IPCT's that have an initial startup... initial startup on or after September 8, 1994, the compliance date shall be the date of the initial startup. ...

40 CFR 63.403 - Compliance dates.

Code of Federal Regulations, 2011 CFR

2011-07-01

... compliance date shall be 18 months after September 8, 1994. (b) For new IPCT's that have an initial startup... initial startup on or after September 8, 1994, the compliance date shall be the date of the initial startup. ...

Physical and relational bullying and victimization: Differential relations with adolescent dating and sexual behavior.

PubMed

Dane, Andrew V; Marini, Zopito A; Volk, Anthony A; Vaillancourt, Tracy

2017-04-01

Taking an evolutionary psychological perspective, we investigated whether involvement in bullying as a perpetrator or victim was more likely if adolescents reported having more dating and sexual partners than their peers, an indication of greater engagement in competition for mates. A total of 334 adolescents (173 boys, 160 girls) between the ages of 12 and 16 years (M = 13.6, SD = 1.3), recruited from community youth organizations, completed self-report measures of physical and relational bullying and victimization, as well as dating and sexual behavior. As predicted, pure physical bullying was positively associated with the number of dating and sexual partners, primarily for adolescent boys. Adolescent girls with more dating partners had greater odds of being relational bully-victims, in line with predictions. Finally, adolescent girls with more sexual partners were at greater risk of being physically victimized by peers, and greater involvement with dating and sexual partners was associated with higher odds of being a physical bully-victim. Results are discussed with respect to evolutionary theory and research in which adolescent boys may display strength and athleticism through physical bullying to facilitate intersexual selection, whereas relational bullying may be employed as a strategy to engage in intrasexual competition with rivals for mates. Aggr. Behav. 43:111-122, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Characteristics of starch-based biodegradable composites reinforced with date palm and flax fibers.

PubMed

Ibrahim, Hamdy; Farag, Mahmoud; Megahed, Hassan; Mehanny, Sherif

2014-01-30

The aim of this work is to study the behavior of completely biodegradable starch-based composites containing date palm fibers in the range from 20 to 80 wt%. Hybrid composites containing date palm and flax fibers, 25 wt% each, were also examined. The composites were preheated and then hot pressed at 5 MPa and 160°C for 30 min. SEM investigation showed strong adhesion between fibers and matrix. Density measurements showed very small void fraction (less than 0.142%) for composites containing up to 50 wt% fiber content. Increasing fiber weight fraction up to 50 wt% increased the composite static tensile and flexural mechanical properties (stiffness and strength). Composite thermal stability, water uptake and biodegradation improved with increasing fiber content. The present work shows that starch-based composites with 50 wt% fibers content have the optimum mechanical properties. The hybrid composite of flax and date palm fibers, 25 wt% each, has good properties and provides a competitive eco-friendly candidate for various applications. Copyright © 2013 Elsevier Ltd. All rights reserved.

The US National Tuberculosis Surveillance System: A Descriptive Assessment of the Completeness and Consistency of Data Reported from 2008 to 2012.

PubMed

Yelk Woodruff, Rachel S; Pratt, Robert H; Armstrong, Lori R

2015-01-01

In 2009, the Tuberculosis (TB) Information Management System transitioned into the National TB Surveillance System to allow use of 4 different types of electronic reporting schemes: state-built, commercial, and 2 schemes developed by the Centers for Disease Control and Prevention. Simultaneously, the reporting form was revised to include additional data fields. Describe data completeness for the years 2008-2012 and determine the impact of surveillance changes. Data were categorized into subgroups and assessed for completeness (eg, the percentage of patients dead at diagnosis who had a date of death reported) and consistency (eg, the percentage of patients alive at diagnosis who erroneously had a date of death reported). Reporting jurisdictions were grouped to examine differences by reporting scheme. Each year less than 1% of reported cases had missing information for country of origin, race, or ethnicity. Patients reported as dead at diagnosis had death date (a new data field) missing for 3.6% in 2009 and 4.4% in 2012. From 2010 to 2012, 313 cases (1%) reported as alive at diagnosis had a death date and all of these were reported through state-built or commercial systems. The completeness of reporting for guardian country of birth for pediatric patients (a new data field) ranged from 84% in 2009 to 88.2% in 2011. Despite major changes, completeness has remained high for most data elements in TB surveillance. However, some data fields introduced in 2009 remain incomplete; continued training is needed to improve national TB surveillance data.

Dating violence victimization across the teen years: abuse frequency, number of abusive partners, and age at first occurrence.

PubMed

Bonomi, Amy E; Anderson, Melissa L; Nemeth, Julianna; Bartle-Haring, Suzanne; Buettner, Cynthia; Schipper, Deborah

2012-08-10

Prior longitudinal studies have shown high cumulative dating violence exposure rates among U.S adolescents, with 36 percent of males and 44 percent to 88 percent of females experiencing victimization across adolescence/young adulthood. Despite promising information characterizing adolescents' dating violence experiences longitudinally, prior studies tended to concentrate on physical and sexual types of violence only, and did not report information on the number of times dating violence was experienced across multiple abusive partners. We used a method similar to the timeline follow-back interview to query adolescents about dating violence victimization from age 13 to 19-including dating violence types (physical, sexual, and psychological), frequency, age at first occurrence, and number of abusive partners. A total of 730 subjects were randomly sampled from university registrar records and invited to complete an online survey, which utilized methods similar to the timeline follow-back interview, to retrospectively assess relationship histories and dating violence victimization from age 13 to 19 (eight questions adapted from widely-used surveys covering physical, sexual, and psychological abuse). Then, for each dating violence type, we asked about the number of occurrences, number of abusive partners, and age at first occurrence. Of 341 subjects who completed the survey, we included 297 (64 percent females; 36 percent males) who had a dating partner from age 13 to 19. Fully 64.7 percent of females and 61.7 percent of males reported dating violence victimization between age 13 and 19, with most experiencing multiple occurrences. More than one-third of abused females had two or more abusive partners: controlling behavior (35.6 percent); put downs/name calling (37.0); pressured sex (42.9); insults (44.3); slapped/hit (50.0); and threats (62.5). Males also had two or more abusive partners, as follows: controlling behavior (42.1 percent); insults (51.2); put downs (53

Dating violence victimization across the teen years: Abuse frequency, number of abusive partners, and age at first occurrence

PubMed Central

2012-01-01

Background Prior longitudinal studies have shown high cumulative dating violence exposure rates among U.S adolescents, with 36 percent of males and 44 percent to 88 percent of females experiencing victimization across adolescence/young adulthood. Despite promising information characterizing adolescents’ dating violence experiences longitudinally, prior studies tended to concentrate on physical and sexual types of violence only, and did not report information on the number of times dating violence was experienced across multiple abusive partners. We used a method similar to the timeline follow-back interview to query adolescents about dating violence victimization from age 13 to 19—including dating violence types (physical, sexual, and psychological), frequency, age at first occurrence, and number of abusive partners. Methods A total of 730 subjects were randomly sampled from university registrar records and invited to complete an online survey, which utilized methods similar to the timeline follow-back interview, to retrospectively assess relationship histories and dating violence victimization from age 13 to 19 (eight questions adapted from widely-used surveys covering physical, sexual, and psychological abuse). Then, for each dating violence type, we asked about the number of occurrences, number of abusive partners, and age at first occurrence. Of 341 subjects who completed the survey, we included 297 (64 percent females; 36 percent males) who had a dating partner from age 13 to 19. Results Fully 64.7 percent of females and 61.7 percent of males reported dating violence victimization between age 13 and 19, with most experiencing multiple occurrences. More than one-third of abused females had two or more abusive partners: controlling behavior (35.6 percent); put downs/name calling (37.0); pressured sex (42.9); insults (44.3); slapped/hit (50.0); and threats (62.5). Males also had two or more abusive partners, as follows: controlling behavior (42.1 percent

Defining conservation targets on a landscape-scale

USGS Publications Warehouse

Benscoter, A.M.; Romañach, Stephanie; Brandt, Laura A.

2015-01-01

Conservation planning, the process of deciding how to protect, conserve, enhance and(or) minimize loss of natural and cultural resources, is a fundamental process to achieve conservation success in a time of rapid environmental change. Conservation targets, the measurable expressions of desired resource conditions, are an important tool in biological planning to achieve effective outcomes. Conservation targets provide a focus for planning, design, conservation action, and collaborative monitoring of environmental trends to guide landscape-scale conservation to improve the quality and quantity of key ecological and cultural resources. It is essential to have an iterative and inclusive method to define conservation targets that is replicable and allows for the evaluation of the effectiveness of conservation targets over time. In this document, we describe a process that can be implemented to achieve landscape-scale conservation, which includes defining conservation targets. We also describe what has been accomplished to date (September 2015) through this process for the Peninsular Florida Landscape Conservation Cooperative (PFLCC).

Dual-targeting siRNAs

PubMed Central

Tiemann, Katrin; Höhn, Britta; Ehsani, Ali; Forman, Stephen J.; Rossi, John J.; Sætrom, Pål

2010-01-01

We have developed an algorithm for the prediction of dual-targeting short interfering RNAs (siRNAs) in which both strands are deliberately designed to separately target different mRNA transcripts with complete complementarity. An advantage of this approach versus the use of two separate duplexes is that only two strands, as opposed to four, are competing for entry into the RNA-induced silencing complex. We chose to design our dual-targeting siRNAs as Dicer substrate 25/27mer siRNAs, since design features resembling pre-microRNAs (miRNAs) can be introduced for Dicer processing. Seven different dual-targeting siRNAs targeting genes that are potential targets in cancer therapy have been developed including Bcl2, Stat3, CCND1, BIRC5, and MYC. The dual-targeting siRNAs have been characterized for dual target knockdown in three different cell lines (HEK293, HCT116, and PC3), where they were as effective as their corresponding single-targeting siRNAs in target knockdown. The algorithm developed in this study should prove to be useful for predicting dual-targeting siRNAs in a variety of different targets and is available from http://demo1.interagon.com/DualTargeting/. PMID:20410240

Dating Violence

MedlinePlus

... like hitting, shoving, kicking, biting, or throwing things Emotional abuse like yelling, name-calling, bullying, embarrassing, keeping you ... are very drunk). Dating violence often starts with emotional abuse. You may think that behaviors like calling you ...

40 CFR 63.403 - Compliance dates.

Code of Federal Regulations, 2013 CFR

2013-07-01

... initial startup before September 8, 1994, the compliance date shall be September 8, 1994. (c) For new IPCT's that have an initial startup on or after September 8, 1994, the compliance date shall be the date of the initial startup. ...

40 CFR 63.403 - Compliance dates.

Code of Federal Regulations, 2014 CFR

2014-07-01

... initial startup before September 8, 1994, the compliance date shall be September 8, 1994. (c) For new IPCT's that have an initial startup on or after September 8, 1994, the compliance date shall be the date of the initial startup. ...

40 CFR 63.403 - Compliance dates.

Code of Federal Regulations, 2012 CFR

2012-07-01

... initial startup before September 8, 1994, the compliance date shall be September 8, 1994. (c) For new IPCT's that have an initial startup on or after September 8, 1994, the compliance date shall be the date of the initial startup. ...

33 CFR 239.9 - Effective date.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Effective date. 239.9 Section 239....9 Effective date. These regulations are applicable to all projects not approved by OCE prior to the date of this regulation. ...

Tuberculosis Treatment Completion Rates in Southern New Mexico Colonias.

PubMed

Holden, Maria Arroyo; Huttlinger, Kathleen; Schultz, Pamela; Mullins, Iris; Forster-Cox, Sue

2016-04-01

TB medication completion treatment rates for active TB patients living in impoverished US-Mexico border communities called colonias in southern New Mexico counties are unknown. It might be suspected that residents of colonias have lower completion rates than those living in incorporated and medically more accessible areas. A retrospective record review of closed TB case records from 1993 to 2010 of southern New Mexico border counties, was conducted using a modified version of the New Mexico Department of Health Tuberculosis Targeted Health Assessment/History form (Appendix 1). Study findings reveal that despite their unincorporated status, poorer living conditions and questionable legal status, colonia TB patients had a higher medication completion rate than their non-colonia counterparts. A robust New Mexico TB treatment program contributed to high completion rates with death being the number-one reason for treatment non-completion in both colonia and non-colonias.

A formative evaluation of social media campaign to reduce adolescent dating violence.

PubMed

Lambert, Danielle N; Bishop, Lauren E; Guetig, Stephanie; Frew, Paula M

2014-11-12

The Emory Jane Fonda Center implemented the Start Strong Atlanta social marketing campaign, "Keep It Strong ATL", in 2007 to promote the development of healthy adolescent relationships and to foster the prevention of adolescent dating abuse among 11-14 year olds. A formative evaluation was conducted to understand whether messages directed at the target audience were relevant to the program's relationship promotion and violence prevention goals, and whether the "Web 2.0" social media channels of communication (Facebook, Twitter, YouTube, Flickr, Tumblr, and Pinterest) were reaching the intended audience. Mixed methodologies included qualitative interviews and a key informant focus group, a cross-sectional survey, and web analytics. Qualitative data were analyzed using constant comparative methodology informed by grounded theory. Descriptive statistics were generated from survey data, and web analytics provided user information and traffic patterns. Results indicated that the Keep It Strong ATL social marketing campaign was a valuable community resource that had potential for broader scope and greater reach. The evaluation team learned the importance of reaching adolescents through Web 2.0 platforms, and the need for message dissemination via peers. Survey results indicated that Facebook (ranked 6.5 out of 8) was the highest rated social media outlet overall, and exhibited greatest appeal and most frequent visits, yet analytics revealed that only 3.5% of "likes" were from the target audience. These results indicate that the social media campaign is reaching predominantly women (76.5% of viewership) who are outside of the target age range of 11-14 years. While the social media campaign was successfully launched, the findings indicate the need for a more focused selection of communication channels, timing of media updates to maximize visibility, balancing message tone and delivery, and incorporating differentiated messaging for the target audiences. Collaboration with

The rate of cyber dating abuse among teens and how it relates to other forms of teen dating violence.

PubMed

Zweig, Janine M; Dank, Meredith; Yahner, Jennifer; Lachman, Pamela

2013-07-01

To date, little research has documented how teens might misuse technology to harass, control, and abuse their dating partners. This study examined the extent of cyber dating abuse-abuse via technology and new media-in youth relationships and how it relates to other forms of teen dating violence. A total of 5,647 youth from ten schools in three northeastern states participated in the survey, of which 3,745 reported currently being in a dating relationship or having been in one during the prior year (52 % were female; 74 % White). Just over a quarter of youth in a current or recent relationship said that they experienced some form of cyber dating abuse victimization in the prior year, with females reporting more cyber dating abuse victimization than males (particularly sexual cyber dating abuse). One out of ten youth said that they had perpetrated cyber dating abuse, with females reporting greater levels of non-sexual cyber dating abuse perpetration than males; by contrast, male youth were significantly more likely to report perpetrating sexual cyber dating abuse. Victims of sexual cyber dating abuse were seven times more likely to have also experienced sexual coercion (55 vs. 8 %) than were non-victims, and perpetrators of sexual cyber dating abuse were 17 times more likely to have also perpetrated sexual coercion (34 vs. 2 %) than were non-perpetrators. Implications for practice and future research are discussed.

Complete Mechanism of Hemithioindigo Motor Rotation.

PubMed

Wilcken, Roland; Schildhauer, Monika; Rott, Florian; Huber, Ludwig Alexander; Guentner, Manuel; Thumser, Stefan; Hoffmann, Kerstin; Oesterling, Sven; de Vivie-Riedle, Regina; Riedle, Eberhard; Dube, Henry

2018-04-18

Hemithioindigo-based molecular motors are powered by nondamaging visible light and provide very fast directional rotations at ambient conditions. Their ground state energy profile has been probed in detail, but the crucial excited state processes are completely unknown so far. In addition, very fast processes in the ground state are also still elusive to date and thus knowledge of the whole operational mechanism remains to a large extent in the dark. In this work we elucidate the complete light-driven rotation mechanism by a combination of multiscale broadband transient absorption measurements covering a time scale from fs to ms in conjunction with a high level theoretical description of the excited state. In addition to a full description of the excited state dynamics in the various time regimes, we also provide the first experimental evidence for the elusive fourth intermediate ground state of the original HTI motor. The fate of this intermediate also is followed directly proving complete unidirectionality for both 180° rotation steps. At the same time, we uncover the hitherto unknown involvement of an unproductive triplet state pathway, which slightly diminishes the quantum yield of the E to Z photoisomerization. A rate model analysis shows that increasing the speed of motor rotation is most effectively done by increasing the photoisomerization quantum yields instead of barrier reduction for the thermal ratcheting steps. Our findings are of crucial importance for improved future designs of any light-driven molecular motor in general to yield better efficiencies and applicability.

Co-Targeting HER2 and EphB4 Pathways

DTIC Science & Technology

2013-07-01

progress has been made toward the clinic. An IND has been obtained for sEphbB4- HSA, an albumin stabilized soluble EphB4 decoy receptor that efficiently...for activated HER2/HER family receptors , angiogenic markers (EphrinB2, EphB1,2,3,4,6, VEGF, VEGFR-1, 2, 3 and PDGFR), vessel density, signal...ABOVE ADDRESS. 1. REPORT DATE 2. REPORT TYPE 3 . DATES COVERED 4. TITLE AND SUBTITLE Co-Targeting HER2 and EphB4 Pathways 5a. CONTRACT NUMBER 5b

Improving Diagnosis of Sepsis After Burn Injury Using a Portable Sepsis Alert System

DTIC Science & Technology

2016-10-01

application listed milestones/target dates for important activities or phases of the project, identify these dates and show actual completion dates or the... activities ; 2) specific objectives; 3) significant results or key outcomes, including major findings, developments, or conclusions (both positive and...progresses to completion, the emphasis in reporting in this section should shift from reporting activities to reporting accomplishments. Task 1. Test the

Completeness and accuracy of the wisconsin immunization registry: an evaluation coinciding with the beginning of meaningful use.

PubMed

Koepke, Ruth; Petit, Ashley B; Ayele, Roman A; Eickhoff, Jens C; Schauer, Stephanie L; Verdon, Matthew J; Hopfensperger, Daniel J; Conway, James H; Davis, Jeffrey P

2015-01-01

Vaccination coverage rates can be improved through the application of complete and accurate immunization information systems (IISs). Evaluate the completeness and accuracy of Wisconsin's IIS, the Wisconsin Immunization Registry (WIR). Cross-sectional evaluation, comparing vaccination medical records (MRs) from provider clinics with WIR records. Medical records of patients born during 2009 were randomly selected from 251 Wisconsin clinics associated with the Vaccines for Children Program. Completeness: percentage of patients with client records in the WIR, percentage of patients up-to-date (%UTD) with the 4:3:1:3:3:1:4 vaccination series, and percentage of patients' MR vaccinations matched by administration date (±10 days) and type to vaccinations documented in the WIR. Accuracy: percentages of matched vaccinations with the same administration date, same trade name (TN), and same lot number. Of the 1863 selected patient MRs, 98% (n = 1833) had WIR client records and 97% of their 30 899 vaccinations were documented in the WIR. The %UTD was 49.3% using the MR only, 76.5% using the WIR only, and 75.2% as estimated by the National Immunization Survey. Among matched vaccinations, 99% had the same administration date, 96% had the same TN, and 95% had the same lot number. Compared with patients from clinics that entered data into the WIR using data exchange from electronic health records, patients from clinics that entered data using the Web-based user interface were less likely to have client records in the WIR (odds ratio: 0.3; 95% confidence interval: 0.1-0.9) and less likely to have accurate TNs (odds ratio: 0.3; 95% confidence interval: 0.1-0.5). The WIR was complete and accurate among this sample of children born during 2009 and provided a vaccination coverage assessment similar to the National Immunization Survey. Our results provide support for the expectation that meaningful use and other initiatives that increase data exchange from electronic health records to

76 FR 44872 - Effective Date of Requirement for Premarket Approval for an Implantable Pacemaker Pulse Generator

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-27

... triggered, inhibited, and asynchronous devices implanted in the human body. B. Summary of Data The... human body. * * * * * (c) Date PMA or notice of completion of PDP is required. A PMA or notice of... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 870 [Docket No...

Correlates of cyber dating abuse among teens.

PubMed

Zweig, Janine M; Lachman, Pamela; Yahner, Jennifer; Dank, Meredith

2014-08-01

Recent advancements in technology (e.g., social networking, texting) have created new ways for dating youth to relate to one another, including in abusive ways via "cyber dating abuse." Cyber dating abuse is a form of teen dating violence that overlaps with other types of abuse (e.g., psychological) but also has several unique characteristics. Given the phenomenon's limited presence in dating violence literature, we focus on identifying how experiencing cyber dating abuse relates to youths' individual behaviors and experiences (e.g., substance use, sexual activity), psychosocial adjustment, school connection, family relationships, and partner relationships. A total of 3,745 youth (52% female, 74% White) in three northeastern states participated in the survey and reported currently being in a dating relationship or having been in one during the prior year. We found that experiences of cyber dating abuse were most significantly correlated with being female, committing a greater variety of delinquent behaviors, having had sexual activity in one's lifetime, having higher levels of depressive symptoms, and having higher levels of anger/hostility. Further, cyber dating abuse appeared somewhat more strongly related to depressive symptoms and delinquency than did other forms of teen dating violence and abuse.

Dating of Submarine Landslides and Their Tsunami Deposits Using Hawaii as an Example

NASA Astrophysics Data System (ADS)

McMurtry, G. M.; Herrero-Bervera, E.

2003-12-01

There have been several approaches to dating the initiation of submarine landslides and the tsunamis they inevitably produce. In Hawaii, the timing of flank failures of major volcanoes has been estimated by radiometric and paleomagnetic dating of the youngest shield-building flows and dikes, the apex ages of the volcanoes, which can also be constrained by the oldest flows of post-collapse volcanism. More precise age estimates can be obtained by direct dating of the landslide. These approaches include paleomagnetic and U-series stratigraphic dating of the overlying pelagic sediment cover upon and in front of the landslide, the latter method producing minimum ages of last landslide turbidite emplacement, e.g., the ca. 120 ka Alika phase 2 event. Elevated, detached landslide blocks make the best targets for such dating because it is assumed that smaller post-emplacement turbidites will not reach their summits. Catastrophic events such as the 1.0 Ma Wailau giant landslide have, however, been dated by turbidite deposition upon large, elevated blocks of the nearby 1.8 Ma Nuuanu giant landslide. Other direct methods for older events include use of thickness of ferromanganese crusts collected from steep, exposed rock scarps and cosmogenic Be-10 or U-series radiometric determination of the few mm/Ma rate of accumulation. In subtropical areas such as Hawaii, coral clast-bearing, elevated marine deposits on the southeastern islands have been identified as deposits from giant tsunamis. Among the key evidence are the great age and paleo-elevations of the coral clasts found in situ. Since modern coral clasts are relatively young, a few thousand years old or less, older analogs swept from the presently submerged reefs offshore can reliably date tsunamigenic depositional events within the late Quaternary using U-series methods. The age of the tsunami will date within these limits (and the analytical precisions) to the youngest in situ coral clast that was entrained by the waves. U

19 CFR 351.701 - Applicability dates.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 3 2010-04-01 2010-04-01 false Applicability dates. 351.701 Section 351.701 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE ANTIDUMPING AND COUNTERVAILING DUTIES Applicability Dates § 351.701 Applicability dates. The regulations contained in this part 351...

19 CFR 351.701 - Applicability dates.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 3 2011-04-01 2011-04-01 false Applicability dates. 351.701 Section 351.701 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE ANTIDUMPING AND COUNTERVAILING DUTIES Applicability Dates § 351.701 Applicability dates. The regulations contained in this part 351...

19 CFR 351.701 - Applicability dates.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 3 2013-04-01 2013-04-01 false Applicability dates. 351.701 Section 351.701 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE ANTIDUMPING AND COUNTERVAILING DUTIES Applicability Dates § 351.701 Applicability dates. The regulations contained in this part 351...

19 CFR 351.701 - Applicability dates.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 3 2014-04-01 2014-04-01 false Applicability dates. 351.701 Section 351.701 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE ANTIDUMPING AND COUNTERVAILING DUTIES Applicability Dates § 351.701 Applicability dates. The regulations contained in this part 351...

19 CFR 351.701 - Applicability dates.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 3 2012-04-01 2012-04-01 false Applicability dates. 351.701 Section 351.701 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE ANTIDUMPING AND COUNTERVAILING DUTIES Applicability Dates § 351.701 Applicability dates. The regulations contained in this part 351...

Date canning: a new approach for the long time preservation of date.

PubMed

Homayouni, Aziz; Azizi, Aslan; Keshtiban, Ata Khodavirdivand; Amini, Amir; Eslami, Ahad

2015-04-01

Dramatic growth in date (Phoenix dactylifera L.) production, makes it clear to apply proper methods to preserve this nutritious fruit for a long time. Numerous methods have been used to gain this goal in recent years that can be classified into non-thermal (fumigation, ozonation, irradiation, and packaging) and thermal (heat treatment, cold storage, dehydration, jam etc.) processing methods. In this paper these methods were reviewed and novel methods for date preservation were presented.

New Radiocarbon Dates on Upper Mid-West Proboscideans: Determining Date Robustness

NASA Astrophysics Data System (ADS)

Hodgins, G.; Widga, C.; Lengyel, S. N.; Saunders, J.; Walker, J. D.

2013-12-01

With the objective of refining the picture of Megafaunal extinction patterns in the upper Midwest in the terminal Pleistocene, we have assembled for radiocarbon dating specimens from more than 80 distinct Mammut and Mammuthus remains from potentially late sites. So far, we have measurements for 65 bones, tusks and teeth, nearly double the extant number of published dates . These new specimens were all from museums rather than excavation sites, and 60% were known to be coated with a consolidant. The predominant consolidant was Butvar B-76, however shellac, Elmer's Glue, Glyptol were also noted in the conservation records, or deduced from knowledge of a particular museum's practices. Given the objective of the project is to identify extinction patterns, coupled with the wide prevalence of consolidants amongst the specimen set, it was imperative that testing be carried out to confirm that radiocarbon laboratory protocols removed the consolidants, so that ultimately the dates can be considered robust. To this end, key specimens were dated three times using different sample preparation protocols. These were 1) a solvent extraction followed by a modified Longin-plus -Base continuous flow collagen extraction method used in the NSF-Arizona AMS facility, 2) the solvent/modified Longin method plus ultrafiltration, and 3) solvent/modified Longin method plus hydroxyproline single amino acid dating. Among the specimens subjected to triplicate testing were some of the youngest late Wisconsin proboscidean specimens from the Upper Midwest Region. The data reveal general agreement between the different protocols, and suggested either limited penetration of consolidants into the specimens, or that the standard laboratory cleaning protocols were sufficient to remove traces from deep within bone, tooth or tusk tissue. The preservation of each specimen, recorded in terms of collagen content, C/N ratio and stable isotope values, indicated that most were actually well preserved, implying

Adolescent Conflict as a Developmental Process in the Prospective Pathway from Exposure to Interparental Violence to Dating Violence

PubMed Central

Narayan, Angela J.; Englund, Michelle M.; Carlson, Elizabeth A.; Egeland, Byron

2013-01-01

Within a developmental psychopathology framework, the current study examined adolescent conflict (age 16) with families, best friends, and dating partners as mediators in the prospective pathway from exposure to interparental violence (EIPV) in early childhood (0–64 months) to dating violence perpetration and victimization in early adulthood (age 23). Adolescent conflict was predicted to partially mediate EIPV and dating violence with significant direct paths from EIPV to dating violence, given the extant literature on the salience of early childhood EIPV for later maladjustment. Participants (N = 182; 99 males, 83 females; 67% Caucasian, 11% African-American, 18% other, 4% unreported) were drawn from a larger prospective study of high-risk mothers (aged 12–34 years) that followed their children from birth through adulthood. EIPV and adolescent conflict were rated from interviews with mothers and participants, and dating violence (physical perpetration and victimization) was assessed with the Conflict Tactics Scale. Path analyses showed that EIPV in early childhood (a) directly predicted dating violence perpetration in early adulthood and (b) predicted conflict with best friends, which in turn predicted dating violence perpetration. Although mediation of best friend conflict was not evident, indirect effects of EIPV to dating violence were found through externalizing behaviors in adolescence and life stress in early adulthood. Findings highlight that conflict with best friends is affected by EIPV and predicts dating violence, suggesting that it may be a promising target for relationship-based interventions for youth with EIPV histories. Furthermore, deleterious early experiences and contemporaneous risk factors are salient predictors of dating violence. PMID:23979004

Dating Norms and Dating Violence among Ninth Graders in Northeast Georgia: Reports from Student Surveys and Focus Groups

ERIC Educational Resources Information Center

Reeves, Patricia M.; Orpinas, Pamela

2012-01-01

This mixed-methods study describes the norms supporting male-to-female and female-to-male dating violence in a diverse sample of ninth graders. The quantitative study, based on student surveys (n = 624), compared norms supporting dating violence by sex, race/ethnicity, and dating status, and it examined the relation between dating violence norms…

49 CFR 571.8 - Effective date.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 6 2010-10-01 2010-10-01 false Effective date. 571.8 Section 571.8 Transportation..., DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE SAFETY STANDARDS General § 571.8 Effective date. (a) Firefighting vehicles. Notwithstanding the effective date provisions of the motor vehicle safety standards in...

49 CFR 1150.13 - Relevant dates.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 8 2011-10-01 2011-10-01 false Relevant dates. 1150.13 Section 1150.13 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT... Designated Operators § 1150.13 Relevant dates. The exact dates of the period of operation which have been...

40 CFR 425.05 - Compliance dates.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 30 2011-07-01 2011-07-01 false Compliance dates. 425.05 Section 425... STANDARDS LEATHER TANNING AND FINISHING POINT SOURCE CATEGORY General Provisions § 425.05 Compliance dates. The compliance date for new source performance standards (NSPS) and pretreatment standards for new...

49 CFR 571.8 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 6 2011-10-01 2011-10-01 false Effective date. 571.8 Section 571.8 Transportation..., DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE SAFETY STANDARDS General § 571.8 Effective date. (a) Firefighting vehicles. Notwithstanding the effective date provisions of the motor vehicle safety standards in...

38 CFR 21.4135 - Discontinuance dates.

Code of Federal Regulations, 2014 CFR

2014-07-01

... withdraws from correspondence, flight, farm cooperative, cooperative or job training, benefits will be... of last instruction. (iii) Job training: Date of last training. (iv) Farm cooperative training: Date... the school or the date determined under § 21.4277, whichever is earlier. (Authority: 38 U.S.C. 3474...

38 CFR 21.4135 - Discontinuance dates.

Code of Federal Regulations, 2012 CFR

2012-07-01

... withdraws from correspondence, flight, farm cooperative, cooperative or job training, benefits will be... of last instruction. (iii) Job training: Date of last training. (iv) Farm cooperative training: Date... the school or the date determined under § 21.4277, whichever is earlier. (Authority: 38 U.S.C. 3474...

Closing the School Completion Gap for Indigenous Students. Resource Sheet No. 6

ERIC Educational Resources Information Center

Helme, Sue; Lamb, Stephen

2011-01-01

School completion rates for Aboriginal and Torres Strait Islander students are well below the rates for non-Indigenous students. The target of halving the gap by 2020 in Year 12 (or equivalent) attainment rates between Indigenous and non-Indigenous students is a major national challenge. This paper discusses the causes of low completion rates for…

Cyclic completion of the anamorphic universe

NASA Astrophysics Data System (ADS)

Ijjas, Anna

2018-04-01

Cyclic models of the universe have the advantage of avoiding initial conditions problems related to postulating any sort of beginning in time. To date, the best known viable examples of cyclic models have been ekpyrotic. In this paper, we show that the recently proposed anamorphic scenario can also be made cyclic. The key to the cyclic completion is a classically stable, non-singular bounce. Remarkably, even though the bounce construction was originally developed to connect a period of contraction with a period of expansion both described by Einstein gravity, we show here that it can naturally be modified to connect an ordinary contracting phase described by Einstein gravity with a phase of anamorphic smoothing. The paper will present the basic principles and steps in constructing cyclic anamorphic models.

One target, different effects: a comparison of distinct therapeutic antibodies against the same targets.

PubMed

Shim, Hyunbo

2011-10-31

To date, more than 30 antibodies have been approved worldwide for therapeutic use. While the monoclonal antibody market is rapidly growing, the clinical use of therapeutic antibodies is mostly limited to treatment of cancers and immunological disorders. Moreover, antibodies against only five targets (TNF-α, HER2, CD20, EGFR, and VEGF) account for more than 80 percent of the worldwide market of therapeutic antibodies. The shortage of novel, clinically proven targets has resulted in the development of many distinct therapeutic antibodies against a small number of proven targets, based on the premise that different antibody molecules against the same target antigen have distinct biological and clinical effects from one another. For example, four antibodies against TNF-α have been approved by the FDA -- infliximab, adalimumab, golimumab, and certolizumab pegol -- with many more in clinical and preclinical development. The situation is similar for HER2, CD20, EGFR, and VEGF, each having one or more approved antibodies and many more under development. This review discusses the different binding characteristics, mechanisms of action, and biological and clinical activities of multiple monoclonal antibodies against TNF-α, HER-2, CD20, and EGFR and provides insights into the development of therapeutic antibodies.

38 CFR 21.9625 - Beginning dates.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Entrance or reentrance including change of program or institution of higher learning. When an eligible... institution of higher learning), the beginning date of his or her award of educational assistance will be... education, the beginning date will be the latest of— (A) The date the institution of higher learning...

40 CFR 62.1352 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 8 2011-07-01 2011-07-01 false Effective date. 62.1352 Section 62.1352 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND... Existing Municipal Solid Waste Landfills § 62.1352 Effective date. The effective date of the plan for...

18 CFR 1308.7 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Effective date. 1308.7... General Matters § 1308.7 Effective date. Subject to § 1308.3(a), this part applies to any TVA contract having an effective date on or after March 1, 1979. ...

40 CFR 62.602 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 8 2011-07-01 2011-07-01 false Effective date. 62.602 Section 62.602 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND... Existing Municipal Solid Waste Landfills § 62.602 Effective date. The effective date of EPA approval of the...

40 CFR 57.106 - Expiration date.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Expiration date. 57.106 Section 57.106 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PRIMARY NONFERROUS SMELTER ORDERS General § 57.106 Expiration date. Each NSO shall state its expiration date. No NSO...

18 CFR 1308.7 - Effective date.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Effective date. 1308.7... General Matters § 1308.7 Effective date. Subject to § 1308.3(a), this part applies to any TVA contract having an effective date on or after March 1, 1979. ...

40 CFR 62.632 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 8 2011-07-01 2011-07-01 false Effective date. 62.632 Section 62.632 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND.../medical/infectious Waste Incinerators § 62.632 Effective date. The effective date of EPA approval of the...

40 CFR 280.91 - Compliance dates.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 27 2011-07-01 2011-07-01 false Compliance dates. 280.91 Section 280... (UST) Financial Responsibility § 280.91 Compliance dates. Owners of petroleum underground storage tanks are required to comply with the requirements of this subpart by the following dates: (a) All petroleum...

Targeted Proteomics Predicts a Sustained Complete-Response after Transarterial Chemoembolization and Clinical Outcomes in Patients with Hepatocellular Carcinoma: A Prospective Cohort Study.

PubMed

Yu, Su Jong; Kim, Hyunsoo; Min, Hophil; Sohn, Areum; Cho, Young Youn; Yoo, Jeong-Ju; Lee, Dong Hyeon; Cho, Eun Ju; Lee, Jeong-Hoon; Gim, Jungsoo; Park, Taesung; Kim, Yoon Jun; Kim, Chung Yong; Yoon, Jung-Hwan; Kim, Youngsoo

2017-03-03

This study was aimed to identify blood-based biomarkers to predict a sustained complete response (CR) after transarterial chemoembolization (TACE) using targeted proteomics. Consecutive patients with HCC who had undergone TACE were prospectively enrolled (training (n = 100) and validation set (n = 80)). Serum samples were obtained before and 6 months after TACE. Treatment responses were evaluated using the modified Response Evaluation Criteria in Solid Tumors (mRECIST). In the training set, the MRM-MS assay identified five marker candidate proteins (LRG1, APCS, BCHE, C7, and FCN3). When this five-marker panel was combined with the best-performing clinical variables (tumor number, baseline PIVKA, and baseline AFP), the resulting ensemble model had the highest area under the receiver operating curve (AUROC) value in predicting a sustained CR after TACE in the training and validation sets (0.881 and 0.813, respectively). Furthermore, the ensemble model was an independent predictor of rapid progression (hazard ratio (HR), 2.889; 95% confidence interval (CI), 1.612-5.178; P value < 0.001) and overall an unfavorable survival rate (HR, 1.985; 95% CI, 1.024-3.848; P value = 0.042) in the entire population by multivariate analysis. Targeted proteomics-based ensemble model can predict clinical outcomes after TACE. Therefore, this model can aid in determining the best candidates for TACE and the need for adjuvant therapy.

40 CFR 63.1351 - Compliance dates.

Code of Federal Regulations, 2013 CFR

2013-07-01

... or startup for sources that commenced construction after March 24, 1998. (b) The compliance date for... before or on December 20, 2006, or (2) Startup for sources that commenced construction after December 20... compliance date for new sources is February 12, 2013, or startup, whichever is later. (e) The compliance date...

40 CFR 63.1351 - Compliance dates.

Code of Federal Regulations, 2014 CFR

2014-07-01

... or startup for sources that commenced construction after March 24, 1998. (b) The compliance date for... before or on December 20, 2006, or (2) Startup for sources that commenced construction after December 20... compliance date for new sources is February 12, 2013, or startup, whichever is later. (e) The compliance date...

10 CFR 784.13 - Effective dates.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Effective dates. 784.13 Section 784.13 Energy DEPARTMENT OF ENERGY PATENT WAIVER REGULATION § 784.13 Effective dates. Waivers shall be effective on the following dates: (a) For advance waivers of identified inventions, i.e., inventions conceived prior to the...

40 CFR 63.784 - Compliance dates.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 10 2011-07-01 2011-07-01 false Compliance dates. 63.784 Section 63... Emission Standards for Shipbuilding and Ship Repair (Surface Coating) § 63.784 Compliance dates. (a) Each owner or operator of an existing affected source shall comply within two years after the effective date...

1 CFR 20.7 - Deadline dates.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 1 General Provisions 1 2010-01-01 2010-01-01 false Deadline dates. 20.7 Section 20.7 General... DOCUMENTS HANDLING OF THE UNITED STATES GOVERNMENT MANUAL STATEMENTS § 20.7 Deadline dates. The Manual is... basis. Therefore, agencies must comply with the deadline dates established by the Director of the...

10 CFR 784.13 - Effective dates.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Effective dates. 784.13 Section 784.13 Energy DEPARTMENT OF ENERGY PATENT WAIVER REGULATION § 784.13 Effective dates. Waivers shall be effective on the following dates: (a) For advance waivers of identified inventions, i.e., inventions conceived prior to the...

Considerations for successful cosmogenic 3He dating in accessory phases

NASA Astrophysics Data System (ADS)

Amidon, W. H.; Farley, K. A.; Rood, D. H.

2008-12-01

We have been working to develop cosmogenic 3He dating of phases other than the commonly dated olivine and pyroxene, especially apatite and zircon. Recent work by Dunai et al. underscores that cosmogenic 3He dating is complicated by 3He production via 6Li(n,α) 3H --> 3He. The reacting thermal neutrons can be produced from three distinct sources; nucleogenic processes (3Henuc), muon interactions (3Hemu), and by high-energy "cosmogenic" neutrons (3Hecn). Accurate cosmogenic 3He dating requires determination of the relative fractions of Li-derived and spallation derived 3He. An important complication for the fine-grained phases we are investigating is that both spallation and the 6Li reaction eject high energy particles, with consequences for redistribution of 3He among phases in a rock. Although shielded samples can be used to estimate 3Henuc, they do not conatin the 3Hecn component produced in the near surface. To calculate this component, we propose a procedure in which the bulk rock chemistry, helium closure age, 3He concentration, grain size and Li content of the target mineral are measured in a shielded sample. The average Li content of the adjacent minerals can then be calculated, which in turn allows calculation of the 3Hecn component in surface exposed samples of the same lithology. If identical grain sizes are used in the shielded and surface exposed samples, then "effective" Li can be calculated directly from the shielded sample, and it may not be necessary to measure Li at all. To help validate our theoretical understanding of Li-3He production, and to constrain the geologic contexts in which cosmogenic 3He dating with zircon and apatite is likely to be successful, results are presented from four different field locations. For example, results from ~18 Ky old moraines in the Sierra Nevada show that the combination of low Li contents and high closure ages (>50 My) creates a small 3Hecn component (2%) but a large 3Henuc component (40-70%) for zircon and

38 CFR 21.7131 - Commencing dates.

Code of Federal Regulations, 2010 CFR

2010-07-01

... standard college degree. (1) When the student enrolls in a course offered by independent study, the commencing date of the award or increased award of educational assistance will be the date the student began...) When a student enrolls in a resident course or subject, the commencing date of the award or increased...

38 CFR 21.7635 - Discontinuance dates.

Code of Federal Regulations, 2012 CFR

2012-07-01

...-Educational Assistance § 21.7635 Discontinuance dates. The effective date of reduction or discontinuance of... mitigating circumstances VA will terminate or reduce educational assistance effective the first date of the... practices of the institution of higher learning. (Authority: 10 U.S.C. 16136(b), 38 U.S.C. 3680(a); Pub. L...

38 CFR 21.7635 - Discontinuance dates.

Code of Federal Regulations, 2011 CFR

2011-07-01

...-Educational Assistance § 21.7635 Discontinuance dates. The effective date of reduction or discontinuance of... mitigating circumstances VA will terminate or reduce educational assistance effective the first date of the... practices of the institution of higher learning. (Authority: 10 U.S.C. 16136(b), 38 U.S.C. 3680(a); Pub. L...

38 CFR 21.7635 - Discontinuance dates.

Code of Federal Regulations, 2014 CFR

2014-07-01

...-Educational Assistance § 21.7635 Discontinuance dates. The effective date of reduction or discontinuance of... mitigating circumstances VA will terminate or reduce educational assistance effective the first date of the... practices of the institution of higher learning. (Authority: 10 U.S.C. 16136(b), 38 U.S.C. 3680(a); Pub. L...

38 CFR 21.7635 - Discontinuance dates.

Code of Federal Regulations, 2010 CFR

2010-07-01

...-Educational Assistance § 21.7635 Discontinuance dates. The effective date of reduction or discontinuance of... mitigating circumstances VA will terminate or reduce educational assistance effective the first date of the... practices of the institution of higher learning. (Authority: 10 U.S.C. 16136(b), 38 U.S.C. 3680(a); Pub. L...

38 CFR 21.7635 - Discontinuance dates.

Code of Federal Regulations, 2013 CFR

2013-07-01

...-Educational Assistance § 21.7635 Discontinuance dates. The effective date of reduction or discontinuance of... mitigating circumstances VA will terminate or reduce educational assistance effective the first date of the... practices of the institution of higher learning. (Authority: 10 U.S.C. 16136(b), 38 U.S.C. 3680(a); Pub. L...

40 CFR 63.826 - Compliance dates.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 10 2011-07-01 2011-07-01 false Compliance dates. 63.826 Section 63... Emission Standards for the Printing and Publishing Industry § 63.826 Compliance dates. (a) The compliance date for an owner or operator of an existing affected source subject to the provisions of this subpart...

29 CFR 18.1104 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 1 2011-07-01 2011-07-01 false Effective date. 18.1104 Section 18.1104 Labor Office of the... ADMINISTRATIVE LAW JUDGES Rules of Evidence Applicability § 18.1104 Effective date. These rules are effective thirty days after date of publication with respect to formal adversarial adjudications as specified in...

46 CFR 565.7 - Effective dates.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 9 2011-10-01 2011-10-01 false Effective dates. 565.7 Section 565.7 Shipping FEDERAL... CARRIERS § 565.7 Effective dates. (a) Generally. Except for service contracts, the rates, charges... permission, become effective sooner than the 30th day after the date of publication. (b) Open rates—(1...

40 CFR 1043.5 - Effective dates.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 33 2011-07-01 2011-07-01 false Effective dates. 1043.5 Section 1043.5... Effective dates. (a) The requirement of APPS for marine vessels to comply with Annex VI of the MARPOL... 1, 2010, although some requirements do not become applicable until later dates. (c) Compliance with...

21 CFR 610.50 - Date of manufacture.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Date of manufacture. 610.50 Section 610.50 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS GENERAL BIOLOGICAL PRODUCTS STANDARDS Dating Period Limitations § 610.50 Date of manufacture. The date of...

21 CFR 610.50 - Date of manufacture.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Date of manufacture. 610.50 Section 610.50 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS GENERAL BIOLOGICAL PRODUCTS STANDARDS Dating Period Limitations § 610.50 Date of manufacture. The date of...

21 CFR 610.50 - Date of manufacture.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Date of manufacture. 610.50 Section 610.50 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS GENERAL BIOLOGICAL PRODUCTS STANDARDS Dating Period Limitations § 610.50 Date of manufacture. The date of...

21 CFR 610.50 - Date of manufacture.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Date of manufacture. 610.50 Section 610.50 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS GENERAL BIOLOGICAL PRODUCTS STANDARDS Dating Period Limitations § 610.50 Date of manufacture. The date of...

7 CFR 35.8 - Date of export.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false Date of export. 35.8 Section 35.8 Agriculture... Practices), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS EXPORT GRAPES AND PLUMS Definitions § 35.8 Date of export. Date of export means the date of loading on board the...

Acceptability of dating violence and expectations of relationship harm among adolescent girls exposed to intimate partner violence.

PubMed

Lee, Michelle Seulki; Begun, Stephanie; DePrince, Anne P; Chu, Ann T

2016-07-01

Little is known about the factors that contribute to adolescents' perceptions of the acceptability of dating violence, particularly among girls who have witnessed intimate partner violence (IPV). Drawing on relevant theory, the current study tests a path model linking frequency of witnessing IPV in childhood, sexist beliefs, and automatic relationship-to-harm associations to acceptability of dating violence. Participants were 79 female adolescents with a mean age of 16.08 years (SD = 1.52) involved in the child welfare system. Participants self-reported frequency of witnessing IPV in childhood, ambivalent sexism, and acceptability of dating violence. A lexical-decision task assessed implicit relationship-to-harm priming, which reflects the degree to which people automatically assume that relationships include harm. Consistent with hypotheses, frequency of witnessing IPV was significantly associated with strength of implicit relationship-to-harm associations. Implicit relationship-to-harm associations and hostile sexism were significantly associated with girls' attitudes that dating violence is acceptable. There was a significant indirect effect of witnessing IPV and acceptability of dating violence through relationship-to-harm associations. The current study provides information that is relevant to dating violence intervention among adolescent girls. Interventions that target girls' schema about relationships-making explicit that healthy relationships do not involve harm-and include education about sexism in society are likely to decrease dating violence risk over time. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Interparental conflict and adolescent dating relationships: the role of perceived threat and self-blame appraisals.

PubMed

Kim, Kerri L; Jackson, Yo; Hunter, Heather L; Conrad, Selby M

2009-05-01

In line with the cognitive-contextual framework proposed by Grych and Fincham (1990), evidence suggests that children exposed to interparental conflict (IPC) are at risk for experiencing conflict within their own intimate relationships. The mediating role of adolescent appraisal in the relation between IPC and adolescent dating behavior was examined in the current study. Specifically, it was hypothesized that self-blame and threat appraisals would mediate the relation between IPC and adolescent maladaptive dating behaviors. To examine the potential mediating role of appraisal, 169 high school students completed the Children's Perception of Interparental Conflict (Grych, Seid, & Fincham, 1992) and Child and Adolescent Dating Relationships Inventory (Wolfe, Scott, Reitzel-Jaffe, Wekerle, Grasley, & Straatman, 2004). Findings suggest that self-blame appraisal partially mediated the relation between IPC and adolescent sexual aggression, and between IPC and adolescent threatening behavior. In addition, perceived threat appraisal partially mediated the relation between IPC and adolescent sexual aggression. Implications for the current findings are discussed.

42 CFR 423.40 - Effective dates.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 3 2011-10-01 2011-10-01 false Effective dates. 423.40 Section 423.40 Public... Effective dates. (a) Initial enrollment period. (1) An enrollment made prior to the month of entitlement to... period specified in § 423.38(c), the effective date is determined by CMS, which, to the extent...

33 CFR 106.110 - Compliance dates.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Compliance dates. 106.110 Section... MARINE SECURITY: OUTER CONTINENTAL SHELF (OCS) FACILITIES General § 106.110 Compliance dates. (a) On or... TWIC under this part may enroll beginning after the date set by the Coast Guard in a Notice to be...

33 CFR 105.115 - Compliance dates.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Compliance dates. 105.115 Section... MARITIME SECURITY: FACILITIES General § 105.115 Compliance dates. (a) On or before December 31, 2003... required to obtain a TWIC under this part may enroll beginning after the date set by the Coast Guard in a...

24 CFR 30.5 - Effective dates.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Effective dates. 30.5 Section 30.5... MONEY PENALTIES: CERTAIN PROHIBITED CONDUCT General § 30.5 Effective dates. (a) Under § 30.20, a civil... dates: (1) September 6, 1996, for owners of more than four residential dwellings; or (2) December 6...

49 CFR 30.5 - Effective dates.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 1 2011-10-01 2011-10-01 false Effective dates. 30.5 Section 30.5 Transportation... SERVICES OF COUNTRIES THAT DENY PROCUREMENT MARKET ACCESS TO U.S. CONTRACTORS § 30.5 Effective dates. The... date of enactment, and before October 1, 1988. The provisions of section 115 of the Airport Safety Act...

42 CFR 435.914 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 4 2011-10-01 2011-10-01 false Effective date. 435.914 Section 435.914 Public... Eligibility § 435.914 Effective date. (a) The agency must make eligibility for Medicaid effective no later... during that month. (c) The State plan must specify the date on which eligibility will be made effective...

40 CFR 51.1004 - Attainment dates.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 2 2014-07-01 2014-07-01 false Attainment dates. 51.1004 Section 51....5 National Ambient Air Quality Standards § 51.1004 Attainment dates. (a) Consistent with section 172(a)(2)(A) of the Act, the attainment date for an area designated nonattainment for the PM2.5 NAAQS...

40 CFR 51.1004 - Attainment dates.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 2 2012-07-01 2012-07-01 false Attainment dates. 51.1004 Section 51....5 National Ambient Air Quality Standards § 51.1004 Attainment dates. (a) Consistent with section 172(a)(2)(A) of the Act, the attainment date for an area designated nonattainment for the PM2.5 NAAQS...

40 CFR 51.1004 - Attainment dates.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Attainment dates. 51.1004 Section 51....5 National Ambient Air Quality Standards § 51.1004 Attainment dates. (a) Consistent with section 172(a)(2)(A) of the Act, the attainment date for an area designated nonattainment for the PM2.5 NAAQS...

School Counselors' Role in Dating Violence Intervention

ERIC Educational Resources Information Center

Craigen, Laurie M.; Sikes, April; Healey, Amanda; Hays, Danica

2009-01-01

Dating violence among adolescents is a major public health concern. The purpose of this paper is to examine five factors of which school counselors must be aware in order to recognize, intervene, and report incidence of dating violence. These factors are (a) understanding the diverse definitions of dating violence, (b) recognizing dating violence…

7 CFR 987.45 - Withholding restricted dates.

Code of Federal Regulations, 2010 CFR

2010-01-01

... purchase on the open market a volume of dates equivalent to the deferred obligation. Such bonding rate..., with the approval of the Secretary, minimum standards for inspection of field-run dates and appropriate..., satisfy all or any part of his obligation to withhold restricted dates by setting aside field-run dates or...

Peptide receptor targeting in cancer: the somatostatin paradigm.

PubMed

Barbieri, Federica; Bajetto, Adriana; Pattarozzi, Alessandra; Gatti, Monica; Würth, Roberto; Thellung, Stefano; Corsaro, Alessandro; Villa, Valentina; Nizzari, Mario; Florio, Tullio

2013-01-01

Peptide receptors involved in pathophysiological processes represent promising therapeutic targets. Neuropeptide somatostatin (SST) is produced by specialized cells in a large number of human organs and tissues. SST primarily acts as inhibitor of endocrine and exocrine secretion via the activation of five G-protein-coupled receptors, named sst1-5, while in central nervous system, SST acts as a neurotransmitter/neuromodulator, regulating locomotory and cognitive functions. Critical points of SST/SST receptor biology, such as signaling pathways of individual receptor subtypes, homo- and heterodimerization, trafficking, and cross-talk with growth factor receptors, have been extensively studied, although functions associated with several pathological conditions, including cancer, are still not completely unraveled. Importantly, SST exerts antiproliferative and antiangiogenic effects on cancer cells in vitro, and on experimental tumors in vivo. Moreover, SST agonists are clinically effective as antitumor agents for pituitary adenomas and gastro-pancreatic neuroendocrine tumors. However, SST receptors being expressed by tumor cells of various tumor histotypes, their pharmacological use is potentially extendible to other cancer types, although to date no significant results have been obtained. In this paper the most recent findings on the expression and functional roles of SST and SST receptors in tumor cells are discussed.

21 CFR 610.50 - Date of manufacture.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Date of manufacture. 610.50 Section 610.50 Food... GENERAL BIOLOGICAL PRODUCTS STANDARDS Dating Period Limitations § 610.50 Date of manufacture. The date of manufacture shall be determined as follows: (a) For products for which an official standard of potency is...

Evolution of Magnetized Liner Inertial Fusion (MagLIF) Targets

DOE PAGES

Fooks, J. A.; Carlson, L. C.; Fitzsimmons, P.; ...

2017-12-19

Here, the magnetized liner inertial fusion (MagLIF) experimental campaign conducted at the University of Rochester’s Laboratory for Laser Energetics (LLE) has evolved significantly since its start in 2014. Scientific requirements and OMEGA EP system technology both have progressed, resulting in necessary and available updates to the target design. These include, but are not limited to: optimizing target dimensions and aspect ratios to maximize survival at desired pressures; coating target components to enhance physics diagnosis; precision-machining diagnostic windows along the axis of the target; improving fiducial placement reproducibility and reducing subsequent assembly time by 50%; and implementing gas-pressure transducers on themore » targets. In addition, target fabrication techniques have changed and improved, allowing for simpler target reproducibility and decreased assembly time. To date, eleven variations of targets have been fabricated, with successful target fielding ranging from 1 to 20atm internal pressure and a maximum survivability of 33atm.« less

Evolution of Magnetized Liner Inertial Fusion (MagLIF) Targets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fooks, J. A.; Carlson, L. C.; Fitzsimmons, P.

Here, the magnetized liner inertial fusion (MagLIF) experimental campaign conducted at the University of Rochester’s Laboratory for Laser Energetics (LLE) has evolved significantly since its start in 2014. Scientific requirements and OMEGA EP system technology both have progressed, resulting in necessary and available updates to the target design. These include, but are not limited to: optimizing target dimensions and aspect ratios to maximize survival at desired pressures; coating target components to enhance physics diagnosis; precision-machining diagnostic windows along the axis of the target; improving fiducial placement reproducibility and reducing subsequent assembly time by 50%; and implementing gas-pressure transducers on themore » targets. In addition, target fabrication techniques have changed and improved, allowing for simpler target reproducibility and decreased assembly time. To date, eleven variations of targets have been fabricated, with successful target fielding ranging from 1 to 20atm internal pressure and a maximum survivability of 33atm.« less

Predictors of Substance Abuse Assessment and Treatment Completion for Parents Involved with Child Welfare: One State's Experience in Matching across Systems.

PubMed

Traube, Dorian E; He, Amy S; Zhu, Limei; Scalise, Christine; Richardson, Tyrone

2015-01-01

To date, few studies have examined the effect of interagency collaboration on substance abuse assessment ity of Southern California and treatment completion for parents who are involved in child welfare. The purpose of this paper is to: (1) describe a statewide, interagency collaborative program aimed at providing targeted substance abuse assessment and treatment to parents engaged in the child welfare system; (2) document the specialized assessment and treatment outcomes for parents engaged through this collaborative program; and (3) determine factors related to successful treatment completion for parents involved in the child welfare system. This is a retrospective study of an open cohort of 13,829 individuals admitted to the New Jersey Child Protection Substance Abuse Initiative (CPSAI) program from October 1, 2009, through September 30, 2010. Data were drawn from two unique administrative data sources. Multivariate Cox regression models were used to explore factors related to successfil treatment completion for parents involved in the child welfare system. Trend analysis for the total sample in the CPSAI program revealed that, of the 10,909 individuals who received a CPSAI assessment, 59% were referred to treatment. Of those referred to treatment, 40% enrolled in a treatment program. Once enrolled in a treatment program, 55% completed or were in the process of completing substance abuse treatment. These findings suggest that when adequate screening and treatment is available through a streamlined process, many of the ethnic and gender disparities present among other populations of individuals seeking treatment are minimized. Utilizing inherent child welfare case factors appears to be an important motivating element that aids parents during the assessment and treatment process.

75 FR 57252 - Designated Transfer Date

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-20

.... Section 1062 of the CFP Act, in relevant part, requires the Secretary to designate a single calendar date... Section 1062(a)(1) requires the Secretary to consult with the heads of the seven ``transferor agencies... 1062(c)(1), select a date between 6 and 12 months after the date of enactment of the CFP Act as the...

20 CFR 217.16 - Filing date.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Filing date. 217.16 Section 217.16 Employees... LUMP SUM Filing An Application § 217.16 Filing date. An application filed in a manner and form acceptable to the Board is officially filed with the Board on the earliest of the following dates: (a) On the...

36 CFR 1258.16 - Effective date.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Effective date. 1258.16... AVAILABILITY AND USE FEES § 1258.16 Effective date. The fees in this part are effective on October 1, 2007. If your order was received by NARA before this effective date, we will charge the fees in effect at the...

36 CFR 1258.16 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Effective date. 1258.16... AVAILABILITY AND USE FEES § 1258.16 Effective date. The fees in this part are effective on October 1, 2007. If your order was received by NARA before this effective date, we will charge the fees in effect at the...

Dating violence and suicidal behavior in adolescents.

PubMed

Holmes, Kristin; Sher, Leo

2013-01-01

The aim of this paper is to assess the possible consequences of adolescent physical, emotional and sexual dating violence through a review of the literature on the topic. An electronic search of major biomedical bibliographic databases (Pubmed, ISI, PsycINFO) was used to retrieve articles providing information on the prevalence rates, risk factors, associated consequences and possible preventive measures for adolescent dating violence across different populations. Currently, there have been few longitudinal studies conducted to identify potential risk factors for entering a violent dating relationship in adolescence. Risky behaviors such as early sexual intercourse may predispose someone for victimization. Dating violence itself is also a predictor of future dating violence. Adolescent dating violence was associated with an increase in other violence-related behaviors, substance use, depression, poorer educational outcomes, posttraumatic stress, unhealthy weight control and risky sexual behavior. The association between adolescent dating violence and an increase in suicidal behavior is a major public health concern. Future research should focus on longitudinal studies so that a causal relationship between dating violence and suicidality may be better understood.

National Date Palm Germplasm Repository

USDA-ARS?s Scientific Manuscript database

The National Clonal Germplasm Repository for Citrus & Dates (NCGRCD), located in Riverside, California USA, is a project of the Agricultural Research Service (ARS) of the United States Department of Agriculture (USDA). The NCGRCD maintains a collection of germplasm of date palm (Phoneix dactylifera ...

46 CFR 188.10-1 - Anniversary date.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Anniversary date. 188.10-1 Section 188.10-1 Shipping... PROVISIONS Definition of Terms Used in This Subchapter § 188.10-1 Anniversary date. The term anniversary date means the day and the month of each year, which corresponds to the date of expiration of the Certificate...

Test Operations Procedure (TOP) 03-2-827 Test Procedures for Video Target Scoring Using Calibration Lights

DTIC Science & Technology

2016-04-04

Final 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE Test Operations Procedure (TOP) 03-2-827 Test Procedures for Video Target Scoring Using...ABSTRACT This Test Operations Procedure (TOP) describes typical equipment and procedures to setup and operate a Video Target Scoring System (VTSS) to...lights. 15. SUBJECT TERMS Video Target Scoring System, VTSS, witness screens, camera, target screen, light pole 16. SECURITY