A new type industrial total station based on target automatic collimation

NASA Astrophysics Data System (ADS)

Lao, Dabao; Zhou, Weihu; Ji, Rongyi; Dong, Dengfeng; Xiong, Zhi; Wei, Jiang

2018-01-01

In the case of industrial field measurement, the present measuring instruments work with manual operation and collimation, which give rise to low efficiency for field measurement. In order to solve the problem, a new type industrial total station is presented in this paper. The new instrument can identify and trace cooperative target automatically, in the mean time, coordinate of the target is measured in real time. For realizing the system, key technology including high precision absolutely distance measurement, small high accuracy angle measurement, target automatic collimation with vision, and quick precise controlling should be worked out. After customized system assemblage and adjustment, the new type industrial total station will be established. As the experiments demonstrated, the coordinate accuracy of the instrument is under 15ppm in the distance of 60m, which proved that the measuring system is feasible. The result showed that the total station can satisfy most industrial field measurement requirements.

Methodology for designing psychological habitability for the space station.

PubMed

Komastubara, A

2000-09-01

Psychological habitability is a critical quality issue for the International Space Station because poor habitability degrades performance shaping factors (PSFs) and increases human errors. However, habitability often receives rather limited design attention based on someone's superficial tastes because systematic design procedures lack habitability quality. To improve design treatment of psychological habitability, this paper proposes and discusses a design methodology for designing psychological habitability for the International Space Station.

Natural environment design criteria for the Space Station definition and preliminary design

NASA Astrophysics Data System (ADS)

Vaughan, W. W.; Green, C. E.

1985-03-01

The natural environment design criteria for the Space Station Program (SSP) definition and preliminary design are presented. Information on the atmospheric, dynamic and thermodynamic environments, meteoroids, radiation, magnetic fields, physical constants, etc. is provided with the intension of enabling all groups involved in the definition and preliminary design studies to proceed with a common and consistent set of natural environment criteria requirements. The space station program elements (SSPE) shall be designed with no operational sensitivity to natural environment conditions during assembly, checkout, stowage, launch, and orbital operations to the maximum degree practical.

Natural environment design criteria for the Space Station definition and preliminary design

NASA Technical Reports Server (NTRS)

Vaughan, W. W.; Green, C. E.

1985-01-01

The natural environment design criteria for the Space Station Program (SSP) definition and preliminary design are presented. Information on the atmospheric, dynamic and thermodynamic environments, meteoroids, radiation, magnetic fields, physical constants, etc. is provided with the intension of enabling all groups involved in the definition and preliminary design studies to proceed with a common and consistent set of natural environment criteria requirements. The space station program elements (SSPE) shall be designed with no operational sensitivity to natural environment conditions during assembly, checkout, stowage, launch, and orbital operations to the maximum degree practical.

Apollo experience report: Crew station integration. Volume 1: Crew station design and development

NASA Technical Reports Server (NTRS)

Allen, L. D.; Nussman, D. A.

1976-01-01

An overview of the evolution of the design and development of the Apollo command module and lunar module crew stations is given, with emphasis placed on the period from 1964 to 1969. The organizational planning, engineering techniques, and documentation involved are described, and a detailed chronology of the meetings, reviews, and exercises is presented. Crew station anomalies for the Apollo 7 to 11 missions are discussed, and recommendations for the solution of recurring problems of crew station acoustics, instrument glass failure, and caution and warning system performance are presented. Photographs of the various crew station configurations are also provided.

Photovoltaic central station step and touch potential considerations in grounding system design

NASA Technical Reports Server (NTRS)

Engmann, G.

1983-01-01

The probability of hazardous step and touch potentials is an important consideration in central station grounding system design. Steam turbine generating station grounding system design is based on accepted industry practices and there is extensive in-service experience with these grounding systems. A photovoltaic (PV) central station is a relatively new concept and there is limited experience with PV station grounding systems. The operation and physical configuration of a PV central station is very different from a steam electric station. A PV station bears some similarity to a substation and the PV station step and touch potentials might be addressed as they are in substation design. However, the PV central station is a generating station and it is appropriate to examine the effect that the differences and similarities of the two types of generating stations have on step and touch potential considerations.

The influence of subway station design on noise levels.

PubMed

Shah, Ravi R; Suen, Jonathan J; Cellum, Ilana P; Spitzer, Jaclyn B; Lalwani, Anil K

2017-05-01

To investigate the impact of subway station design on platform noise levels. Observational. Continuous A-weighted decibel (dBA) sound levels were recorded in 20 New York City subway stations, where trains entered on either a straight track or curved track in 10 stations each. Equivalent continuous noise levels (L eq ) at various locations on the boarding platform (inbound end, midplatform, and outbound end) during train entry and exit were compared between the straight and curved stations in broadband as well as narrow one-third octave bands. Overall, curved stations trended louder than straight stations, although the difference in broadband L eq did not reach statistical significance (curve, 83.4 dBA; straight, 82.6 dBA; P = .054). Noise levels were significantly louder at the inbound end of the platform during train entry (inbound, 89.7 dBA; mid, 85.5 dBA; outbound, 78.7 dBA; P < .001) and at the outbound end during train exit (inbound, 79.7 dBA; mid, 85.3 dBA; outbound, 89.1 dBA; P < .001). Narrow band analysis showed that curved stations were significantly louder than straight stations at 100 Hz and high frequencies from 8 to 20 kHz. Peak impact levels ranged from 104 to 121 dBA. Curved stations have a different noise profile compared to straight stations and are significantly louder than straight stations at high frequencies. Designing stations with straight tracks within the platform can help reduce commuter noise exposure. NA Laryngoscope, 127:1169-1174, 2017. © 2016 The American Laryngological, Rhinological and Otological Society, Inc.

An approach to design knowledge capture for the space station

NASA Technical Reports Server (NTRS)

Wechsler, D. B.; Crouse, K. R.

1986-01-01

The design of NASA's space station has begun. During the design cycle, and after activation of the space station, the reoccurring need will exist to access not only designs, but also deeper knowledge about the designs, which is only hinted in the design definition. Areas benefiting from this knowledge include training, fault management, and onboard automation. NASA's Artificial Intelligence Office at Johnson Space Center and The MITRE Corporation have conceptualized an approach for capture and storage of design knowledge.

An Approach To Design Knowledge Capture For The Space Station

NASA Astrophysics Data System (ADS)

Wechsler, D. B.; Crouse, K. R.

1987-02-01

Design of NASA's Space Station has begun. During the design cycle, and after activation of the Space Station, the reoccuring need will exist to access not only designs; but also deeper knowledge about the designs, which is only hinted in the design definition. Areas benefiting from this knowledge include training, fault management, and onboard automation. NASA's Artificial Intelligence Office at Johnson Space Center and The MITRE Corporation have conceptualized an approach for capture and storage of design knowledge.

An approach to design knowledge capture for the space station

NASA Technical Reports Server (NTRS)

Wechsler, D. B.; Crouse, K. R.

1987-01-01

The design of NASA's space station has begun. During the design cycle, and after activation of the space station, the reoccurring need will exist to access not only designs, but also deeper knowledge about the designs, which is only hinted in the design definition. Areas benefiting from this knowledge include training, fault management, and onboard automation. NASA's Artificial Intelligence Office at Johnson Space Center and The MITRE Corporation have conceptualized an approach for capture and storage of design knowledge.

GLRS-R 2-colour retroreflector target design and predicted performance

NASA Astrophysics Data System (ADS)

Lund, Glenn

The retroreflector ground target design for the GLRS-R spaceborne dual wavelength laser ranging system is described. The passive design flows down from the requirements of high station autonomy, high global field of view, little or no multiple pulse returns, and adequate optical cross section for most ranging geometries. The solution makes use of five hollow cube corner retroreflectors of which one points to the zenith and the remaining four are inclined from the vertical at uniform azimuthal spacings. The need for large retroreflectors is expected to generate narrow diffraction lobes. A good compromise solution is found by spoiling just one of the retroereflector dihedral angles from 90 deg, thus generating two symmetrically oriented diffraction lobes in the return beam. The required spoil angles are found to have little dependance on ground target latitude. Various link budget analyses are presented. They show the influence of such factors as point ahead optimization, turbulence, ranging angle, atmospheric visibility, and ground target thermal deformations.

Small space station electrical power system design concepts

NASA Technical Reports Server (NTRS)

Jones, G. M.; Mercer, L. N.

1976-01-01

A small manned facility, i.e., a small space station, placed in earth orbit by the Shuttle transportation system would be a viable, cost effective addition to the basic Shuttle system to provide many opportunities for R&D programs, particularly in the area of earth applications. The small space station would have many similarities with Skylab. This paper presents design concepts for an electrical power system (EPS) for the small space station based on Skylab experience, in-house work at Marshall Space Flight Center, SEPS (Solar Electric Propulsion Stage) solar array development studies, and other studies sponsored by MSFC. The proposed EPS would be a solar array/secondary battery system. Design concepts expressed are based on maximizing system efficiency and five year operational reliability. Cost, weight, volume, and complexity considerations are inherent in the concepts presented. A small space station EPS based on these concepts would be highly efficient, reliable, and relatively inexpensive.

Space Station Freedom pressurized element interior design process

NASA Technical Reports Server (NTRS)

Hopson, George D.; Aaron, John; Grant, Richard L.

1990-01-01

The process used to develop the on-orbit working and living environment of the Space Station Freedom has some very unique constraints and conditions to satisfy. The goal is to provide maximum efficiency and utilization of the available space, in on-orbit, zero G conditions that establishes a comfortable, productive, and safe working environment for the crew. The Space Station Freedom on-orbit living and working space can be divided into support for three major functions: (1) operations, maintenance, and management of the station; (2) conduct of experiments, both directly in the laboratories and remotely for experiments outside the pressurized environment; and (3) crew related functions for food preparation, housekeeping, storage, personal hygiene, health maintenance, zero G environment conditioning, and individual privacy, and rest. The process used to implement these functions, the major requirements driving the design, unique considerations and constraints that influence the design, and summaries of the analysis performed to establish the current configurations are described. Sketches and pictures showing the layout and internal arrangement of the Nodes, U.S. Laboratory and Habitation modules identify the current design relationships of the common and unique station housekeeping subsystems. The crew facilities, work stations, food preparation and eating areas (galley and wardroom), and exercise/health maintenance configurations, waste management and personal hygiene area configuration are shown. U.S. Laboratory experiment facilities and maintenance work areas planned to support the wide variety and mixtures of life science and materials processing payloads are described.

Project EGRESS: Earthbound Guaranteed Reentry from Space Station. the Design of an Assured Crew Recovery Vehicle for the Space Station

NASA Technical Reports Server (NTRS)

1990-01-01

Unlike previously designed space-based working environments, the shuttle orbiter servicing the space station will not remain docked the entire time the station is occupied. While an Apollo capsule was permanently available on Skylab, plans for Space Station Freedom call for a shuttle orbiter to be docked at the space station for no more than two weeks four times each year. Consideration of crew safety inspired the design of an Assured Crew Recovery Vehicle (ACRV). A conceptual design of an ACRV was developed. The system allows the escape of one or more crew members from Space Station Freedom in case of emergency. The design of the vehicle addresses propulsion, orbital operations, reentry, landing and recovery, power and communication, and life support. In light of recent modifications in space station design, Project EGRESS (Earthbound Guaranteed ReEntry from Space Station) pays particular attention to its impact on space station operations, interfaces and docking facilities, and maintenance needs. A water-landing medium-lift vehicle was found to best satisfy project goals of simplicity and cost efficiency without sacrificing safety and reliability requirements. One or more seriously injured crew members could be returned to an earth-based health facility with minimal pilot involvement. Since the craft is capable of returning up to five crew members, two such permanently docked vehicles would allow a full evacuation of the space station. The craft could be constructed entirely with available 1990 technology, and launched aboard a shuttle orbiter.

Design of an MSAT-X mobile transceiver and related base and gateway stations

NASA Technical Reports Server (NTRS)

Fang, Russell J. F.; Bhaskar, Udaya; Hemmati, Farhad; Mackenthun, Kenneth M.; Shenoy, Ajit

1987-01-01

This paper summarizes the results of a design study of the mobile transceiver, base station, and gateway station for NASA's proposed Mobile Satellite Experiment (MSAT-X). Major ground segment system design issues such as frequency stability control, modulation method, linear predictive coding vocoder algorithm, and error control technique are addressed. The modular and flexible transceiver design is described in detail, including the core, RF/IF, modem, vocoder, forward error correction codec, amplitude-companded single sideband, and input/output modules, as well as the flexible interface. Designs for a three-carrier base station and a 10-carrier gateway station are also discussed, including the interface with the controllers and with the public-switched telephone networks at the gateway station. Functional specifications are given for the transceiver, the base station, and the gateway station.

Design of an MSAT-X mobile transceiver and related base and gateway stations

NASA Astrophysics Data System (ADS)

Fang, Russell J. F.; Bhaskar, Udaya; Hemmati, Farhad; Mackenthun, Kenneth M.; Shenoy, Ajit

This paper summarizes the results of a design study of the mobile transceiver, base station, and gateway station for NASA's proposed Mobile Satellite Experiment (MSAT-X). Major ground segment system design issues such as frequency stability control, modulation method, linear predictive coding vocoder algorithm, and error control technique are addressed. The modular and flexible transceiver design is described in detail, including the core, RF/IF, modem, vocoder, forward error correction codec, amplitude-companded single sideband, and input/output modules, as well as the flexible interface. Designs for a three-carrier base station and a 10-carrier gateway station are also discussed, including the interface with the controllers and with the public-switched telephone networks at the gateway station. Functional specifications are given for the transceiver, the base station, and the gateway station.

QMI: Rising to the Space Station Design Challenge

NASA Astrophysics Data System (ADS)

Carswell, W. E.; Farmer, J.; Coppens, C.; Breeding, S.; Rose, F.

2002-01-01

The Quench Module Insert (QMI) materials processing furnace is being designed to operate for 8000 hours over four years on the International Space Station as part of the first Materials Science Research Rack of the Materials Science Research Facility. The Bridgman-type furnace is being built for the directional solidification processing of metals and alloys in the microgravity environment of space. Most notably it will be used for processing aluminum and related alloys. Designing for the space station environment presents intriguing design challenges in the form of a ten-year life requirement coupled with both limited opportunities for maintenance and resource constraints in the form of limited power and space. The long life requirement has driven the design of several features in the furnace, including the design of the heater core, the selection and placement of the thermocouples, overall performance monitoring, and the design of the chill block. The power and space limitations have been addressed through a compact furnace design using efficient vacuum insulation. Details on these design features, as well as development test performance results to date, are presented.

Design and operation of a Loran-C time reference station

NASA Technical Reports Server (NTRS)

Putkovich, K.

1974-01-01

Some of the practical questions that arise when one decides to use Loran-C in a time reference system are explored. An extensive effort is made to provide basic, practical information on establishing and operating a reference station. Four areas were covered: (1) the design, configuration and operational concepts which should be considered prior to establishing and operating a reference station using Loran-C, (2) the options and tradeoffs available regarding capabilities, cost, size, versatility, ease of operation, etc., that are available to the designer, (3) what measurements are made, how they are made and what they mean, and (4) the experience the U.S. Naval Observatory Time Service Division has had in the design and operation of such stations.

QMI: Rising to the Space Station Design Challenge

NASA Technical Reports Server (NTRS)

Carswell, W. E.; Farmer, J.; Coppens, C.; Breeding, S.; Rose, F.; Curreri, Peter A. (Technical Monitor)

2002-01-01

The Quench Module Insert (QMI) materials processing furnace is being designed to operate for 8000 hours over four years on the International Space Station (ISS) as part of the first Materials Science Research Rack (MSRR-1) of the Materials Science Research Facility (MSRF). The Bridgman-type furnace is being built for the directional solidification processing of metals and alloys in the microgravity environment of space. Most notably it will be used for processing aluminum and related alloys. Designing for the space station environment presents intriguing design challenges in the form of a ten-year life requirement coupled with both limited opportunities for maintenance and resource constraints in the form of limited power and space. The long life requirement has driven the design of several features in the furnace, including the design of the heater core, the selection and placement of the thermocouples, overall performance monitoring, and the design of the chill block. The power and space limitations have been addressed through a compact furnace design using efficient vacuum insulation. Details on these design features, as well as development test performance results to date, are presented.

Expert-guided evolutionary algorithm for layout design of complex space stations

NASA Astrophysics Data System (ADS)

Qian, Zhiqin; Bi, Zhuming; Cao, Qun; Ju, Weiguo; Teng, Hongfei; Zheng, Yang; Zheng, Siyu

2017-08-01

The layout of a space station should be designed in such a way that different equipment and instruments are placed for the station as a whole to achieve the best overall performance. The station layout design is a typical nondeterministic polynomial problem. In particular, how to manage the design complexity to achieve an acceptable solution within a reasonable timeframe poses a great challenge. In this article, a new evolutionary algorithm has been proposed to meet such a challenge. It is called as the expert-guided evolutionary algorithm with a tree-like structure decomposition (EGEA-TSD). Two innovations in EGEA-TSD are (i) to deal with the design complexity, the entire design space is divided into subspaces with a tree-like structure; it reduces the computation and facilitates experts' involvement in the solving process. (ii) A human-intervention interface is developed to allow experts' involvement in avoiding local optimums and accelerating convergence. To validate the proposed algorithm, the layout design of one-space station is formulated as a multi-disciplinary design problem, the developed algorithm is programmed and executed, and the result is compared with those from other two algorithms; it has illustrated the superior performance of the proposed EGEA-TSD.

SDTM - SYSTEM DESIGN TRADEOFF MODEL FOR SPACE STATION FREEDOM RELEASE 1.1

NASA Technical Reports Server (NTRS)

Chamberlin, R. G.

1994-01-01

Although extensive knowledge of space station design exists, the information is widely dispersed. The Space Station Freedom Program (SSFP) needs policies and procedures that ensure the use of consistent design objectives throughout its organizational hierarchy. The System Design Tradeoff Model (SDTM) produces information that can be used for this purpose. SDTM is a mathematical model of a set of possible designs for Space Station Freedom. Using the SDTM program, one can find the particular design which provides specified amounts of resources to Freedom's users at the lowest total (or life cycle) cost. One can also compare alternative design concepts by changing the set of possible designs, while holding the specified user services constant, and then comparing costs. Finally, both costs and user services can be varied simultaneously when comparing different designs. SDTM selects its solution from a set of feasible designs. Feasibility constraints include safety considerations, minimum levels of resources required for station users, budget allocation requirements, time limitations, and Congressional mandates. The total, or life cycle, cost includes all of the U.S. costs of the station: design and development, purchase of hardware and software, assembly, and operations throughout its lifetime. The SDTM development team has identified, for a variety of possible space station designs, the subsystems that produce the resources to be modeled. The team has also developed formulas for the cross consumption of resources by other resources, as functions of the amounts of resources produced. SDTM can find the values of station resources, so that subsystem designers can choose new design concepts that further reduce the station's life cycle cost. The fundamental input to SDTM is a set of formulas that describe the subsystems which make up a reference design. Most of the formulas identify how the resources required by each subsystem depend upon the size of the subsystem. Some of

Instructor/Operator Station Design Study.

DTIC Science & Technology

1982-04-01

components interact and are dependent one upon the other. A major issue in any design involving both hardware and software is establishing the proper...always begins at leg 1. The AUTOMATED TRAINING EXER- CISE MAP display calls up a map of the gaming area for the selected exer- cise. The PRINTOUT...select the size of the gaming area in nautical miles. When the Aircraft comes within 100 miles of an in-tune station, the approach display for the in

GLRS-R 2-colour retroreflector target design and predicted performance

NASA Technical Reports Server (NTRS)

Lund, Glenn

1993-01-01

This paper reports on the retroreflector ground-target design for the GLRS-R spaceborne dual-wavelength laser ranging system. The described passive design flows down from the requirements of high station autonomy, high global FOV (up to 60 degrees zenith angle), little or no multiple pulse returns, and adequate optical cross section for most ranging geometries. The proposed solution makes use of 5 hollow cube-corner retroreflectors of which one points to the zenith and the remaining four are inclined from the vertical at uniform azimuthal spacings. The need for fairly large (is approximately 10 cm) retroreflectors is expected (within turbulence limitations) to generate quite narrow diffraction lobes, thus placing non-trivial requirements on the vectorial accuracy of velocity aberration corrections. A good compromise solution is found by appropriately spoiling just one of the retroreflector dihedral angles from 90 degrees, thus generating two symmetrically oriented diffraction lobes in the return beam. The required spoil angles are found to have little dependence on ground target latitude. Various link budget analyses are presented, showing the influence of such factors as point-ahead optimization, turbulence, ranging angle, atmospheric visibility and ground target thermal deformations.

GLRS-R 2-colour retroreflector target design and predicted performance

NASA Astrophysics Data System (ADS)

Lund, Glenn

1993-06-01

This paper reports on the retroreflector ground-target design for the GLRS-R spaceborne dual-wavelength laser ranging system. The described passive design flows down from the requirements of high station autonomy, high global FOV (up to 60 degrees zenith angle), little or no multiple pulse returns, and adequate optical cross section for most ranging geometries. The proposed solution makes use of 5 hollow cube-corner retroreflectors of which one points to the zenith and the remaining four are inclined from the vertical at uniform azimuthal spacings. The need for fairly large (is approximately 10 cm) retroreflectors is expected (within turbulence limitations) to generate quite narrow diffraction lobes, thus placing non-trivial requirements on the vectorial accuracy of velocity aberration corrections. A good compromise solution is found by appropriately spoiling just one of the retroreflector dihedral angles from 90 degrees, thus generating two symmetrically oriented diffraction lobes in the return beam. The required spoil angles are found to have little dependence on ground target latitude. Various link budget analyses are presented, showing the influence of such factors as point-ahead optimization, turbulence, ranging angle, atmospheric visibility and ground target thermal deformations.

Design of a resistojet for Space Station Freedom

NASA Technical Reports Server (NTRS)

Garza, Jose; Reisman, Jill; Tapia, Jose; Wright, Anthony

1993-01-01

In the mid 1990's, NASA will begin assembly of Space Station Freedom, a permanent outpost in a low-earth orbit. For the station to remain in that orbit, an altitude control system must be developed to resist the effects of atmospheric drag. One system being considered by NASA is called a resistojet, and it uses highly pressurized waste gases heated by electrical resistance to provide thrust on the order of 1 Newton. An additional function of the resistojet is to vent waste gases used by the station and its inhabitants. This report focuses on resolving the issues of system performance, flow and heater control, and materials selection and designing test procedures to resolve, by experimentation, any remaining issues. The conceptual model of the resistojet consists of a shell wrapped by a resistive coil with gases flowing internally through the tube with additional components such as regulators, transducers, and thermocouples. For system performance, the major parameters were calculated from the desired thrust range, the pressure within the resistojet and the cold flow mode of operation; waste gases were analyzed at 100 percent capacity and between 58.95 kPa and 552 kPa. The design team found that any ventilation under all conditions would produce thrust, and therefore, it was decided to limit the design of the ventilation function. The design team proceeded with a simplified model to determine the nozzle throat diameter and chamber diameter.

Habitability design elements for a space station

NASA Technical Reports Server (NTRS)

Dalton, M. C.

1983-01-01

Habitability in space refers to the components, characteristics, conditions, and design parameters that go beyond but include the basic life sustaining requirements. Elements of habitability covered include internal environment, architecture, mobility and restraint, food, clothing, personal hygiene, housekeeping, communications, and crew activities. All elements are interrelated and need to be treated as an overall discipline. Designing for a space station is similar to designing on earth but with 'space rules' instead of ground rules. It is concluded that some habitability problems require behavioral science solutions.

H2FIRST Reference Station Design Task: Project Deliverable 2-2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pratt, Joseph; Terlip, Danny; Ainscough, Chris

2015-04-20

This report presents near-term station cost results and discusses cost trends of different station types. It compares various vehicle rollout scenarios and projects realistic near-term station utilization values using the station infrastructure rollout in California as an example. It describes near-term market demands and matches those to cost-effective station concepts. Finally, the report contains detailed designs for five selected stations, which include piping and instrumentation diagrams, bills of materials, and several site-specific layout studies that incorporate the setbacks required by NFPA 2, the National Fire Protection Association Hydrogen Technologies Code. This work identified those setbacks as a significant factor affectingmore » the ability to site a hydrogen station, particularly liquid stations at existing gasoline stations. For all station types, utilization has a large influence on the financial viability of the station.« less

Ground control station software design for micro aerial vehicles

NASA Astrophysics Data System (ADS)

Walendziuk, Wojciech; Oldziej, Daniel; Binczyk, Dawid Przemyslaw; Slowik, Maciej

2017-08-01

This article describes the process of designing the equipment part and the software of a ground control station used for configuring and operating micro unmanned aerial vehicles (UAV). All the works were conducted on a quadrocopter model being a commonly accessible commercial construction. This article contains a characteristics of the research object, the basics of operating the micro aerial vehicles (MAV) and presents components of the ground control station model. It also describes the communication standards for the purpose of building a model of the station. Further part of the work concerns the software of the product - the GIMSO application (Generally Interactive Station for Mobile Objects), which enables the user to manage the actions and communication and control processes from the UAV. The process of creating the software and the field tests of a station model are also presented in the article.

Space Station services and design features for users

NASA Technical Reports Server (NTRS)

Kurzhals, Peter R.; Mckinney, Royce L.

1987-01-01

The operational design features and services planned for the NASA Space Station will furnish, in addition to novel opportunities and facilities, lower costs through interface standardization and automation and faster access by means of computer-aided integration and control processes. By furnishing a basis for large-scale space exploitation, the Space Station will possess industrial production and operational services capabilities that may be used by the private sector for commercial ventures; it could also ultimately support lunar and planetary exploration spacecraft assembly and launch facilities.

Space station proximity operations windows: Human factors design guidelines

NASA Technical Reports Server (NTRS)

Haines, Richard F.

1987-01-01

Proximity operations refers to all activities outside the Space Station which take place within a 1-km radius. Since there will be a large number of different operations involving manned and unmanned vehicles, single- and multiperson crews, automated and manually controlled flight, a wide variety of cargo, and construction/repair activities, accurate and continuous human monitoring of these operations from a specially designed control station on Space Station will be required. Total situational awareness will be required. This paper presents numerous human factors design guidelines and related background information for control windows which will support proximity operations. Separate sections deal with natural and artificial illumination geometry; all basic rendezvous vector approaches; window field-of-view requirements; window size; shape and placement criteria; window optical characteristics as they relate to human perception; maintenance and protection issues; and a comprehensive review of windows installed on U.S. and U.S.S.R. manned vehicles.

Space station electric power system requirements and design

NASA Technical Reports Server (NTRS)

Teren, Fred

1987-01-01

An overview of the conceptual definition and design of the space station Electric Power System (EPS) is given. Responsibilities for the design and development of the EPS are defined. The EPS requirements are listed and discussed, including average and peak power requirements, contingency requirements, and fault tolerance. The most significant Phase B trade study results are summarized, and the design selections and rationale are given. Finally, the power management and distribution system architecture is presented.

A home away from home. [life support system design for Space Station

NASA Technical Reports Server (NTRS)

Powell, L. E.; Hager, R. W.; Mccown, J. W.

1985-01-01

The role of the NASA-Marshall center in the development of the Space Station is discussed. The tasks of the center include the development of the life-support system; the design of the common module, which will form the basis for all pressurized Space Station modules; the design and outfit of a common module for the Material and Technology Laboratory (MTL) and logistics use; accommodations for operations of the Orbit Maneuvering Vehicle (OMV) and the Orbit Transfer Vehicle (OTV); and the Space Station propulsion system. A description of functions and design is given for each system, with particular emphasis on the goals of safety, efficiency, automation, and cost effectiveness.

Review on Selection and Suitability of Rail Transit Station Design Pertaining to Public Safety

NASA Astrophysics Data System (ADS)

Akabal, Farah Mohd; Masirin, Mohd Idrus Haji Mohd; Abidin Akasah, Zainal; Rohani, Munzilah Md

2017-08-01

Railway has emerged as a fast, convenient, safe, clean, and low-cost alternative to air and road transportation. Many countries have invested in rail transportation. In America, Europe and Asia, large investments are planned for rail transportation. This is because congestion problems can be reduced with the introduction of rail transportation. Rail transportation involves several components which are important to ensure the smooth and safe delivery of services such as locomotives, rail stations and railway tracks. Rail transit stations are places where trains stop to pick-up and drop-off passengers. Stations are vital for many to enable them to engage in work and social commitments. This paper focuses only on the rail transit station as it is one of the important components in rail transportation. It is also considered as a key public meeting place and space for interactions in a community. The role of rail transit station and the requirements of a good rail transit station are also described in this paper. Steps in selecting the location of rail transit station include the function and facilities in rail transit station are discussed with reference to best practices and handbooks. Selection of the appropriate rail transit station locations may help users indirectly. In addition, this paper will also elucidate on the design considerations for an efficient and effective rail transit station. Design selections for the rail transit station must be balanced between aesthetic value and functional efficiency. The right design selection may help conserve energy, assure and facilitate consumers even thought a rail transit station plays a smaller role in attracting consumers compared to a shopping complex or a residential building. This will contribute towards better and greener building for a green transportation facility. Thus, with this paper it is expected to assist the relevant authority to identify important elements in the selection and determination of suitable

Modular space station detailed preliminary design. Volume 1: Sections 1 through 4.4

NASA Technical Reports Server (NTRS)

1971-01-01

Detailed configuration and subsystems preliminary design data are presented for the modular space station concept. Each module comprising the initial space station is described in terms of its external and internal configuration, its functional responsibilities to the initial cluster, and its orbital build up sequence. Descriptions of the subsequent build up to the growth space station are also presented. Analytical and design techniques, tradeoff considerations, and depth of design detail are discussed for each subsystem. The subsystems include the following: structural/mechanical; crew habitability and protection; experiment support; electrical power; environmental control/life support; guidance, navigation, and control; propulsion; communications; data management; and onboard checkout subsystems. The interfaces between the station and other major elements of the program are summarized. The rational for a zero-gravity station, in lieu of one with artificial-gravity capability, is also summarized.

Implementation green and low cost on landscape design of Manggarai Integrated Station, Jakarta

NASA Astrophysics Data System (ADS)

Suryanti, T.; Meilianti, H.

2018-01-01

The Manggarai Integrated Station is the transit of various transportation modes. The Integrated Station located in Manggarai Jakarta and managed by PT. KAI. The Manggarai station is integrated and have terminal nature of transit areas (switching mode of transportation). There are several problems in the site, such as the problem of the site conditions in the urban area, topography, soil, vegetation, space, visual, users on the site can provide ideas for the concepts. The data was analyzed using the quantitative descriptive methode. The purpose of this research is to design the integrated station atmosphere, not only can support of the activities station users, but can also accommodate the needs of the community. It will “Green, Low cost” at the Manggarai integrated transport transit station in Jakarta. The potential that exists in this area is the lowliest integrated from various areas of the mode of transportation that make the users to facilitate transit transportation to the other. The basic concept of this design refers to the “Green, Low Cost” which unite with theme “user friendly” land use on a more efficient and effective site. The result of this research is landscape design development of Manggarai integrated station. Its consists of landscape design in west and east area, transition area, parking area, solar panel area, and social interaction area.

Design of the Space Station Freedom power system

NASA Technical Reports Server (NTRS)

Thomas, Ronald L.; Hallinan, George J.

1989-01-01

The design of Space Station Freedom's electric power system (EPS) is reviewed, highlighting the key design goals of performance, low cost, reliability and safety. Tradeoff study results that illustrate the competing factors responsible for many of the more important design decisions are discussed. When Freedom's EPS is compared with previous space power designs, two major differences stand out. The first is the size of the EPS, which is larger than any prior system. The second major difference between the EPS and other space power designs is the indefinite expected life of Freedom; 30 years has been used for life-cycle-cost calculations.

Spacecraft Station-Keeping Trajectory and Mission Design Tools

NASA Technical Reports Server (NTRS)

Chung, Min-Kun J.

2009-01-01

Two tools were developed for designing station-keeping trajectories and estimating delta-v requirements for designing missions to a small body such as a comet or asteroid. This innovation uses NPOPT, a non-sparse, general-purpose sequential quadratic programming (SQP) optimizer and the Two-Level Differential Corrector (T-LDC) in LTool (Libration point mission design Tool) to design three kinds of station-keeping scripts: vertical hovering, horizontal hovering, and orbiting. The T-LDC is used to differentially correct several trajectory legs that join hovering points. In a vertical hovering, the maximum and minimum range points must be connected smoothly while maintaining the spacecrafts range from a small body, all within the law of gravity and the solar radiation pressure. The same is true for a horizontal hover. A PatchPoint is an LTool class that denotes a space-time event with some extra information for differential correction, including a set of constraints to be satisfied by T-LDC. Given a set of PatchPoints, each with its own constraint, the T-LDC differentially corrects the entire trajectory by connecting each trajectory leg joined by PatchPoints while satisfying all specified constraints at the same time. Vertical and horizontal hover both are needed to minimize delta-v spent for station keeping. A Python I/F to NPOPT has been written to be used from an LTool script. In vertical hovering, the spacecraft stays along the line joining the Sun and a small body. An instantaneous delta-v toward the anti- Sun direction is applied at the closest approach to the small body for station keeping. For example, the spacecraft hovers between the minimum range (2 km) point and the maximum range (2.5 km) point from the asteroid 1989ML. Horizontal hovering buys more time for a spacecraft to recover if, for any reason, a planned thrust fails, by returning almost to the initial position after some time later via a near elliptical orbit around the small body. The mapping or

Space Station Freedom solar array design development

NASA Technical Reports Server (NTRS)

Winslow, Cindy; Bilger, Kevin; Baraona, Cosmo

1989-01-01

The Space Station Freedom solar array program is required to provide a 75-kW power module that uses eight solar array (SA) wings over a four-year period in low earth orbit (LEO). Each wing will be capable of providing 23.4 kW at the 4-yr design point. The design of flexible-substrate SAs that must survive exposure to the space environment, including atomic oxygen, for an operating life of fifteen years is discussed. The tradeoff study and development areas being investigated include solar cell module size, solar cell weld pads, panel stiffener frames, materials inherently resistant to atomic oxygen, and weight reduction design alternatives.

Space station prototype Sabatier reactor design verification testing

NASA Technical Reports Server (NTRS)

Cusick, R. J.

1974-01-01

A six-man, flight prototype carbon dioxide reduction subsystem for the SSP ETC/LSS (Space Station Prototype Environmental/Thermal Control and Life Support System) was developed and fabricated for the NASA-Johnson Space Center between February 1971 and October 1973. Component design verification testing was conducted on the Sabatier reactor covering design and off-design conditions as part of this development program. The reactor was designed to convert a minimum of 98 per cent hydrogen to water and methane for both six-man and two-man reactant flow conditions. Important design features of the reactor and test conditions are described. Reactor test results are presented that show design goals were achieved and off-design performance was stable.

Preliminary design of the Space Station internal thermal control system

NASA Technical Reports Server (NTRS)

Herrin, Mark T.; Patterson, David W.; Turner, Larry D.

1987-01-01

The baseline preliminary design configuration of the Internal Thermal Control system (ITCS) of the U.S. Space Station pressurized elements (i.e., the Habitation and U.S. Laboratory modules, pressurized logistics carrier, and resources nodes) is defined. The ITCS is composed of both active and passive components. The subsystems which comprise the ITCS are identified and their functional descriptions are provided. The significant trades and analyses, which were performed during Phase B (i.e., the preliminary design phase) that resulted in the design described herein, are discussed. The ITCS interfaces with the station's central Heat Rejection and Transport System (HRTS), other systems, and externally attached pressurized payloads are described. Requirements on the ITCS with regard to redundancy and experiment support are also addressed.

Dual keel Space Station payload pointing system design and analysis feasibility study

NASA Technical Reports Server (NTRS)

Smagala, Tom; Class, Brian F.; Bauer, Frank H.; Lebair, Deborah A.

1988-01-01

A Space Station attached Payload Pointing System (PPS) has been designed and analyzed. The PPS is responsible for maintaining fixed payload pointing in the presence of disturbance applied to the Space Station. The payload considered in this analysis is the Solar Optical Telescope. System performance is evaluated via digital time simulations by applying various disturbance forces to the Space Station. The PPS meets the Space Station articulated pointing requirement for all disturbances except Shuttle docking and some centrifuge cases.

Space Station Freedom power management and distribution system design

NASA Technical Reports Server (NTRS)

Teren, Fred

1989-01-01

The design is described of the Space Station Freedom Power Management and Distribution (PMAD) System. In addition, the significant trade studies which were conducted are described, which led to the current PMAD system configuration.

Bio-Medical Factors and External Hazards in Space Station Design

NASA Technical Reports Server (NTRS)

Olling, E. H.

1966-01-01

The design of space-station configurations is influenced by many factors. Probably the most demanding and critical are the biomedical and external hazards requirements imposed to provide the proper environment and supporting facilities for the crew and the adequate protective measures necessary to provide a configuration'in which the crew can live and work efficiently in relative comfort and safety. The major biomedical factors, such as physiology, psychology, nutrition, personal hygiene, waste management, and recreation, all impose their own peculiar requirements. The commonality and integration of these requirements demand the utmost ingenuity and inventiveness be exercised in order to achieve effective configuration compliance. The relationship of biomedical factors for the internal space-station environment will be explored with respect to internal atmospheric constituency, atmospheric pressure levels, oxygen positive pressure, temperature, humidity, CO2 concentration, and atmospheric contamination. The range of these various parameters and the recommended levels for design use will be analyzed. Requirements and criteria for specific problem areas such as zero and artificial gravity and crew private quarters will be reviewed and the impact on the design of representative solutions will be presented. In the areas of external hazards, the impact of factors such as meteoroids, radiation, vacuum, temperature extremes, and cycling on station design will be evaluated. Considerations with respect to operational effectiveness and crew safety will be discussed. The impact of such factors on spacecraft design to achieve acceptable launch and reentry g levels, crew rotation intervals, etc., will be reviewed.

Design and development of electric vehicle charging station equipped with RFID

NASA Astrophysics Data System (ADS)

Panatarani, C.; Murtaddo, D.; Maulana, D. W.; Irawan, S.; Joni, I. M.

2016-02-01

This paper reports the development of electric charging station from distributed renewable for electric vehicle (EV). This designed refer to the input voltage standard of IEC 61851, plugs features of IEC 62196 and standard communication of ISO 15118. The developed electric charging station used microcontroller ATMEGA8535 and RFID as controller and identifier of the EV users, respectively. The charging station successfully developed as desired features for electric vehicle from renewable energy resources grid with solar panel, wind power and batteries storage.

Implementing Target Value Design.

PubMed

Alves, Thais da C L; Lichtig, Will; Rybkowski, Zofia K

2017-04-01

An alternative to the traditional way of designing projects is the process of target value design (TVD), which takes different departure points to start the design process. The TVD process starts with the client defining an allowable cost that needs to be met by the design and construction teams. An expected cost in the TVD process is defined through multiple interactions between multiple stakeholders who define wishes and others who define ways of achieving these wishes. Finally, a target cost is defined based on the expected profit the design and construction teams are expecting to make. TVD follows a series of continuous improvement efforts aimed at reaching the desired goals for the project and its associated target value cost. The process takes advantage of rapid cycles of suggestions, analyses, and implementation that starts with the definition of value for the client. In the traditional design process, the goal is to identify user preferences and find solutions that meet the needs of the client's expressed preferences. In the lean design process, the goal is to educate users about their values and advocate for a better facility over the long run; this way owners can help contractors and designers to identify better solutions. This article aims to inform the healthcare community about tools and techniques commonly used during the TVD process and how they can be used to educate and support project participants in developing better solutions to meet their needs now as well as in the future.

Spaceborne computer executive routine functional design specification. Volume 2: Computer executive design for space station/base

NASA Technical Reports Server (NTRS)

Kennedy, J. R.; Fitzpatrick, W. S.

1971-01-01

The computer executive functional system design concepts derived from study of the Space Station/Base are presented. Information Management System hardware configuration as directly influencing the executive design is reviewed. The hardware configuration and generic executive design requirements are considered in detail in a previous report (System Configuration and Executive Requirements Specifications for Reusable Shuttle and Space Station/Base, 9/25/70). This report defines basic system primitives and delineates processes and process control. Supervisor states are considered for describing basic multiprogramming and multiprocessing systems. A high-level computer executive including control of scheduling, allocation of resources, system interactions, and real-time supervisory functions is defined. The description is oriented to provide a baseline for a functional simulation of the computer executive system.

Space Station automated systems testing/verification and the Galileo Orbiter fault protection design/verification

NASA Technical Reports Server (NTRS)

Landano, M. R.; Easter, R. W.

1984-01-01

Aspects of Space Station automated systems testing and verification are discussed, taking into account several program requirements. It is found that these requirements lead to a number of issues of uncertainties which require study and resolution during the Space Station definition phase. Most, if not all, of the considered uncertainties have implications for the overall testing and verification strategy adopted by the Space Station Program. A description is given of the Galileo Orbiter fault protection design/verification approach. Attention is given to a mission description, an Orbiter description, the design approach and process, the fault protection design verification approach/process, and problems of 'stress' testing.

Space Station Freedom Solar Array design development

NASA Technical Reports Server (NTRS)

Winslow, Cindy; Bilger, Kevin; Baraona, Cosmo R.

1989-01-01

The Space Station Freedom Solar Array Program is required to provide a 75 kW power module that uses eight solar array (SA) wings over a four-year period in low Earth orbit (LEO). Each wing will be capable of providing 23.4 kW at the 4-year design point. Lockheed Missles and Space Company, Inc. (LMSC) is providing the flexible substrate SAs that must survive exposure to the space environment, including atomic oxygen, for an operating life of fifteen years. Trade studies and development testing, important for evolving any design to maturity, are presently underway at LMSC on the flexible solar array. The trade study and development areas being investigated include solar cell module size, solar cell weld pads, panel stiffener frames, materials inherently resistant to atomic oxygen, and weight reduction design alternatives.

Prefocal station mechanical design concept study for the E-ELT

NASA Astrophysics Data System (ADS)

Jolley, Paul; Brunetto, Enzo; Frank, Christoph; Lewis, Steffan; Marchetti, Enrico

2016-07-01

The Nasmyth platforms of the E-ELT will contain one Prefocal Station (PFS) each. The main PFS functional requirements are to provide a focal plane to the three Nasmyth focal stations and the Coudé focus, optical sensing supporting telescope low order optimisation and seeing limited image quality, and optical sensing supporting characterising and phasing of M1 and other telescope subsystems. The PFS user requirements are used to derive the PFS technical requirements specification that will form the basis for design, development and production of the system. This specification process includes high-level architectural decisions and technical performance budget allocations. The mechanical design concepts reported here have been developed in order to validate key system specifications and associated technical budgets.

Space Station Freedom power management and distribution design status

NASA Technical Reports Server (NTRS)

Javidi, S.; Gholdston, E.; Stroh, P.

1989-01-01

The design status of the power management and distribution electric power system for the Space Station Freedom is presented. The current design is a star architecture, which has been found to be the best approach for meeting the requirement to deliver 120 V dc to the user interface. The architecture minimizes mass and power losses while improving element-to-element isolation and system flexibility. The design is partitioned into three elements: energy collection, storage and conversion, system protection and distribution, and management and control.

Status of the Space Station environmental control and life support system design concept

NASA Technical Reports Server (NTRS)

Ray, C. D.; Humphries, W. R.

1986-01-01

The current status of the Space Station (SS) environmental control and life support system (ECLSS) design is outlined. The concept has been defined at the subsystem level. Data supporting these definitions are provided which identify general configuratioons for all modules. Requirements, guidelines and assumptions used in generating these configurations are detailed. The basic 2 US module 'core' Space Station is addressed along with system synergism issues and early man-tended and future growth considerations. Along with these basic studies, also addressed here are options related to variation in the 'core' module makeup and more austere Station concepts such as commonality, automation and design to cost.

Space Station Freedom - Approaching the critical design phase

NASA Technical Reports Server (NTRS)

Kohrs, Richard H.; Huckins, Earle, III

1992-01-01

The status and future developments of the Space Station Freedom are discussed. To date detailed design drawings are being produced to manufacture SSF hardware. A critical design review (CDR) for the man-tended capability configuration is planned to be performed in 1993 under the SSF program. The main objective of the CDR is to enable the program to make a full commitment to proceed to manufacture parts and assemblies. NASA recently signed a contract with the Russian space company, NPO Energia, to evaluate potential applications of various Russian space hardware for on-going NASA programs.

Design and Performance of the Acts Gigabit Satellite Network High Data-Rate Ground Station

NASA Technical Reports Server (NTRS)

Hoder, Doug; Kearney, Brian

1995-01-01

The ACTS High Data-Rate Ground stations were built to support the ACTS Gigabit Satellite Network (GSN). The ACTS GSN was designed to provide fiber-compatible SONET service to remote nodes and networks through a wideband satellite system. The ACTS satellite is unique in its extremely wide bandwidth, and electronically controlled spot beam antennas. This paper discusses the requirements, design and performance of the RF section of the ACTS High Data-Rate Ground Stations and constituent hardware. The ACTS transponder systems incorporate highly nonlinear hard limiting. This introduced a major complexity in to the design and subsequent modification of the ground stations. A discussion of the peculiarities of the A CTS spacecraft transponder system and their impact is included.

NIMROD: The Near and InterMediate Range Order Diffractometer of the ISIS second target station.

PubMed

Bowron, D T; Soper, A K; Jones, K; Ansell, S; Birch, S; Norris, J; Perrott, L; Riedel, D; Rhodes, N J; Wakefield, S R; Botti, A; Ricci, M-A; Grazzi, F; Zoppi, M

2010-03-01

NIMROD is the Near and InterMediate Range Order Diffractometer of the ISIS second target station. Its design is optimized for structural studies of disordered materials and liquids on a continuous length scale that extends from the atomic, upward of 30 nm, while maintaining subatomic distance resolution. This capability is achieved by matching a low and wider angle array of high efficiency neutron scintillation detectors to the broad band-pass radiation delivered by a hybrid liquid water and liquid hydrogen neutron moderator assembly. The capabilities of the instrument bridge the gap between conventional small angle neutron scattering and wide angle diffraction through the use of a common calibration procedure for the entire length scale. This allows the instrument to obtain information on nanoscale systems and processes that are quantitatively linked to the local atomic and molecular order of the materials under investigation.

Application of the first collision source method to CSNS target station shielding calculation

NASA Astrophysics Data System (ADS)

Zheng, Ying; Zhang, Bin; Chen, Meng-Teng; Zhang, Liang; Cao, Bo; Chen, Yi-Xue; Yin, Wen; Liang, Tian-Jiao

2016-04-01

Ray effects are an inherent problem of the discrete ordinates method. RAY3D, a functional module of ARES, which is a discrete ordinates code system, employs a semi-analytic first collision source method to mitigate ray effects. This method decomposes the flux into uncollided and collided components, and then calculates them with an analytical method and discrete ordinates method respectively. In this article, RAY3D is validated by the Kobayashi benchmarks and applied to the neutron beamline shielding problem of China Spallation Neutron Source (CSNS) target station. The numerical results of the Kobayashi benchmarks indicate that the solutions of DONTRAN3D with RAY3D agree well with the Monte Carlo solutions. The dose rate at the end of the neutron beamline is less than 10.83 μSv/h in the CSNS target station neutron beamline shutter model. RAY3D can effectively mitigate the ray effects and obtain relatively reasonable results. Supported by Major National S&T Specific Program of Large Advanced Pressurized Water Reactor Nuclear Power Plant (2011ZX06004-007), National Natural Science Foundation of China (11505059, 11575061), and the Fundamental Research Funds for the Central Universities (13QN34).

Excluding feral swine, javelina and raccoons from deer bait stations

USDA-ARS?s Scientific Manuscript database

Here we present a design and construction procedure for a physical and electric barrier fence to prevent feral swine (Sus scrofa), javelina (Pecari tajacu), raccoons (Procyon lotor), and perhaps other non-target animals from accessing or damaging bait stations designed to administer acaricide treatm...

Excluding feral swine, javelina, and raccoons from deer bait stations

USDA-ARS?s Scientific Manuscript database

This paper presents a design, list of materials, and construction procedure for a physical and electric barrier fence to prevent feral swine (Sus scrofa), javelina (Pecari tajacu), raccoons (Procyon lotor), and perhaps other non-target animals from accessing or damaging bait stations designed to adm...

49 CFR 192.163 - Compressor stations: Design and construction.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Design of... building. Except for a compressor building on a platform located offshore or in inland navigable waters, each main compressor building of a compressor station must be located on property under the control of...

Bio-Medical Factors and External Hazards in Space Station Design

NASA Technical Reports Server (NTRS)

Olling, Edward H.

1966-01-01

The design of space-station configurations is influenced by many factors, Probably the most demanding and critical are the biomedical and external hazards requirements imposed to provide the proper environment and supporting facilities for the crew and the adequate protective measures necessary to provide a configuration in which the crew can live and work efficiently in relative comfort and safety. The major biomedical factors, such as physiology, psychology, nutrition, personal hygiene, waste management, and recreation, all impose their own peculiar requirements. The commonality and integration of these requirements demand the utmost ingenuity and inventiveness be exercised in order to achieve effective configuration compliance. The relationship of biomedical factors for the internal space-station environment will be explored with respect to internal atmospheric constituency, atmospheric pressure levels, oxygen positive pressure, temperature, humidity, CO2 concentration, and atmospheric contamination. The range of these various parameters and the recommended levels for design use will be analyzed. Requirements and criteria for specific problem areas such as zero and artificial gravity and crew private quarters will be reviewed and the impact on the design of representative solutions will be presented. In the areas of external hazards, the impact of factors such as meteoroids, radiation, vacuum, temperature extremes, and cycling on station design will be evaluated. Considerations with respect to operational effectiveness and crew safety will be discussed. The impact of such factors on spacecraft design to achieve acceptable launch and reentry g levels, crew rotation intervals, etc., will be reviewed. Examples of configurations, subsystems, and internal a arrangement and installations to comply with such biomedical factor requirements will ber presented. The effects of solutions to certain biomedical factors on configuration weight, operational convenience, and

Optimization of municipal pressure pumping station layout and sewage pipe network design

NASA Astrophysics Data System (ADS)

Tian, Jiandong; Cheng, Jilin; Gong, Yi

2018-03-01

Accelerated urbanization places extraordinary demands on sewer networks; thus optimization research to improve the design of these systems has practical significance. In this article, a subsystem nonlinear programming model is developed to optimize pumping station layout and sewage pipe network design. The subsystem model is expanded into a large-scale complex nonlinear programming system model to find the minimum total annual cost of the pumping station and network of all pipe segments. A comparative analysis is conducted using the sewage network in Taizhou City, China, as an example. The proposed method demonstrated that significant cost savings could have been realized if the studied system had been optimized using the techniques described in this article. Therefore, the method has practical value for optimizing urban sewage projects and provides a reference for theoretical research on optimization of urban drainage pumping station layouts.

Conceptual design and integration of a space station resistojet propulsion assembly

NASA Technical Reports Server (NTRS)

Tacina, Robert R.

1987-01-01

The resistojet propulsion module is designed as a simple, long life, low risk system offering operational flexibility to the space station program. It can dispose of a wide variety of typical space station waste fluids by using them as propellants for orbital maintenance. A high temperature mode offers relatively high specific impulse with long life while a low temperature mode can propulsively dispose of mixtures that contain oxygen or hydrocarbons without reducing thruster life or generating particulates in the plume. A low duty cycle and a plume that is confined to a small aft region minimizes the impacts on the users. Simple interfaces with other space station systems facilitate integration. It is concluded that there are no major obstacles and many advantages to developing, installing, and operating a resistojet propulsion module aboard the Initial Operational Capability (IOC) space station.

DESIGNING AN OPPORTUNITY FUEL WITH BIOMASS AND TIRE-DERIVED FUEL FOR COFIRING AT WILLOW ISLAND GENERATING STATION AND COFIRING SAWDUST WITH COAL AT ALBRIGHT GENERATING STATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

K. Payette; D. Tillman

During the period April 1, 2003--June 30, 2003, Allegheny Energy Supply Co., LLC (Allegheny) proceeded with demonstration operations at the Willow Island Generating Station and improvements to the Albright Generating Station cofiring systems. The demonstration operations at Willow Island were designed to document integration of biomass cofiring into commercial operations. The Albright improvements were designed to increase the resource base for the projects, and to address issues that came up during the first year of operations. This report summarizes the activities associated with the Designer Opportunity Fuel program, and demonstrations at Willow Island and Albright Generating Stations.

Space Station Furnace Facility. Volume 2: Requirements definition and conceptual design study

NASA Technical Reports Server (NTRS)

1992-01-01

The Space Station Freedom Furnace (SSFF) Project is divided into two phases: phase 1, a definition study phase, and phase 2, a design and development phase. TBE was awarded a research study entitled, 'Space Station Furnace Facility Requirements Definition and Conceptual Design Study' on June 2, 1989. This report addresses the definition study phase only. Phase 2 is to be complete after completion of phase 1. The contract encompassed a requirements definition study and culminated in hardware/facility conceptual designs and hardware demonstration development models to test these conceptual designs. The study was divided into two parts. Part 1 (the basic part of the effort) encompassed preliminary requirements definition and assessment; conceptional design of the SSFF Core; fabrication of mockups; and preparation for the support of a conceptional design review (CoDR). Part 2 (the optional part of the effort) included detailed definition of the engineering and design requirements, as derived from the science requirements; refinement of the conceptual design of the SSFF Core; fabrication and testing of the 'breadboards' or development models; and preparation for and support of a requirements definition review.

From the nurses' station to the health team hub: how can design promote interprofessional collaboration?

PubMed

Gum, Lyn Frances; Prideaux, David; Sweet, Linda; Greenhill, Jennene

2012-01-01

Interprofessional practice implies that health professionals are able to contribute patient care in a collaborative environment. In this paper, it is argued that in a hospital the nurses' station is a form of symbolic power. The term could be reframed as a "health team hub," which fosters a place for communication and interprofessional working. Studies have found that design of the Nurses' Station can impact on the walking distance of hospital staff, privacy for patients and staff, jeopardize patient confidentiality and access to resources. However, no studies have explored the implications of nurses' station design on interprofessional practice. A multi-site collective case study of three rural hospitals in South Australia explored the collaborative working culture of each hospital. Of the cultural concepts being studied, the physical design of nurses' stations and the general physical environment were found to have a major influence on an effective collaborative practice. Communication barriers were related to poor design, lack of space, frequent interruptions and a lack of privacy; the name "nurses' station" denotes the space as the primary domain of nurses rather than a workspace for the healthcare team. Immersive work spaces could encourage all members of the healthcare team to communicate more readily with one another to promote interprofessional collaboration.

DESIGNING AN OPPORTUNITY FUEL WITH BIOMASS AND TIRE-DERIVED FUEL FOR COFIRING AT WILLOW ISLAND GENERATING STATION AND COFIRING SAWDUST WITH COAL AT ALBRIGHT GENERATING STATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

K. Payette; D. Tillman

During the period October 1, 2003-December 31, 2003, Allegheny Energy Supply Co., LLC (Allegheny) continued with demonstration operations at the Willow Island Generating Station and improvements to the Albright Generating Station cofiring systems. The demonstration operations at Willow Island were designed to document integration of biomass cofiring into commercial operations, including evaluating new sources of biomass supply. The Albright improvements were designed to increase the resource base for the projects, and to address issues that came up during the first year of operations. This report summarizes the activities associated with the Designer Opportunity Fuel program, and demonstrations at Willow Islandmore » and Albright Generating Stations.« less

Design of a seismo-acoustic station for Antarctica.

PubMed

Contrafatto, Danilo; Fasone, Rosario; Ferro, Angelo; Larocca, Graziano; Laudani, Giuseppe; Rapisarda, Salvatore; Scuderi, Luciano; Zuccarello, Luciano; Privitera, Eugenio; Cannata, Andrea

2018-04-01

In recent years, seismological studies in Antarctica have contributed plenty of new knowledge in many fields of earth science. Moreover, acoustic investigations are now also considered a powerful tool that provides insights for many different objectives, such as analyses of regional climate-related changes and studies of volcanic degassing and explosive activities. However, installation and maintenance of scientific instrumentation in Antarctica can be really challenging. Indeed, the instruments have to face the most extreme climate on the planet. They must be tolerant of very low temperatures and robust enough to survive strong winds. Moreover, one of the most critical tasks is powering a remote system year-round at polar latitudes. In this work, we present a novel seismo-acoustic station designed to work reliably in polar regions. To enable year-round seismo-acoustic data collection in such a remote, extreme environment, a hybrid powering system is used, integrating solar panels, a wind generator, and batteries. A power management system was specifically developed to either charge the battery bank or divert energy surplus to warm the enclosure or release the excess energy to the outside environment. Finally, due to the prohibitive environmental conditions at most Antarctic installation sites, the station was designed to be deployed quickly.

Design of a seismo-acoustic station for Antarctica

NASA Astrophysics Data System (ADS)

Contrafatto, Danilo; Fasone, Rosario; Ferro, Angelo; Larocca, Graziano; Laudani, Giuseppe; Rapisarda, Salvatore; Scuderi, Luciano; Zuccarello, Luciano; Privitera, Eugenio; Cannata, Andrea

2018-04-01

In recent years, seismological studies in Antarctica have contributed plenty of new knowledge in many fields of earth science. Moreover, acoustic investigations are now also considered a powerful tool that provides insights for many different objectives, such as analyses of regional climate-related changes and studies of volcanic degassing and explosive activities. However, installation and maintenance of scientific instrumentation in Antarctica can be really challenging. Indeed, the instruments have to face the most extreme climate on the planet. They must be tolerant of very low temperatures and robust enough to survive strong winds. Moreover, one of the most critical tasks is powering a remote system year-round at polar latitudes. In this work, we present a novel seismo-acoustic station designed to work reliably in polar regions. To enable year-round seismo-acoustic data collection in such a remote, extreme environment, a hybrid powering system is used, integrating solar panels, a wind generator, and batteries. A power management system was specifically developed to either charge the battery bank or divert energy surplus to warm the enclosure or release the excess energy to the outside environment. Finally, due to the prohibitive environmental conditions at most Antarctic installation sites, the station was designed to be deployed quickly.

Branch target buffer design and optimization

NASA Technical Reports Server (NTRS)

Perleberg, Chris H.; Smith, Alan J.

1993-01-01

Consideration is given to two major issues in the design of branch target buffers (BTBs), with the goal of achieving maximum performance for a given number of bits allocated to the BTB design. The first issue is BTB management; the second is what information to keep in the BTB. A number of solutions to these problems are reviewed, and various optimizations in the design of BTBs are discussed. Design target miss ratios for BTBs are developed, making it possible to estimate the performance of BTBs for real workloads.

Project EGRESS: The design of an assured crew return vehicle for the space station

NASA Technical Reports Server (NTRS)

1990-01-01

Keeping preliminary studies by NASA in mind, an Assured Crew Return Vehicle (ACRV) was developed. The system allows the escape of one or more crew members from Space Station Freedom in case of emergency. The design of the vehicle addresses propulsion, orbital operations, reentry, landing and recovery, power and communication, and life support. In light of recent modifications in Space Station design, Project EGRESS (Earthbound Guaranteed ReEntry from Space Station) pays particular attention to its impact on Space Station operations, interfaces and docking facilities, and maintenance needs. A water landing, medium lift vehicle was found to best satisfy project goals of simplicity and cost efficiency without sacrificing the safety and reliability requirements. With a single vehicle, one injured crew member could be returned to Earth with minimal pilot involvement. Since the craft is capable of returning up to five crew members, two such permanently docked vehicles would allow full evacuation of the Space Station. The craft could be constructed entirely with available 1990 technology and launched aboard a shuttle orbiter.

Design of ligand-targeted nanoparticles for enhanced cancer targeting

NASA Astrophysics Data System (ADS)

Stefanick, Jared F.

Ligand-targeted nanoparticles are increasingly used as drug delivery vehicles for cancer therapy, yet have not consistently produced successful clinical outcomes. Although these inconsistencies may arise from differences in disease models and target receptors, nanoparticle design parameters can significantly influence therapeutic efficacy. By employing a multifaceted synthetic strategy to prepare peptide-targeted nanoparticles with high purity, reproducibility, and precisely controlled stoichiometry of functionalities, this work evaluates the roles of polyethylene glycol (PEG) coating, ethylene glycol (EG) peptide-linker length, peptide hydrophilicity, peptide density, and nanoparticle size on tumor targeting in a systematic manner. These parameters were analyzed in multiple disease models by targeting human epidermal growth factor receptor 2 (HER2) in breast cancer and very late antigen-4 (VLA-4) in multiple myeloma to demonstrate the widespread applicability of this approach. By increasing the hydrophilicity of the targeting peptide sequence and simultaneously optimizing the EG peptide-linker length, the in vitro cellular uptake of targeted liposomes was significantly enhanced. Specifically, including a short oligolysine chain adjacent to the targeting peptide sequence effectively increased cellular uptake ~80-fold using an EG6 peptide-linker compared to ~10-fold using an EG45 linker. In vivo, targeted liposomes prepared in a traditional manner lacking the oligolysine chain demonstrated similar biodistribution and tumor uptake to non-targeted liposomes. However, by including the oligolysine chain, targeted liposomes using an EG45 linker significantly improved tumor uptake ~8-fold over non-targeted liposomes, while the use of an EG6 linker decreased tumor accumulation and uptake, owing to differences in cellular uptake kinetics, clearance mechanisms, and binding site barrier effects. To further improve tumor targeting and enhance the selectivity of targeted

Report on the findings of the Japanese Investigative Team on US Space Station Design (Keidanren)

NASA Technical Reports Server (NTRS)

1985-01-01

The objectives, itinerary and results of the Japanese Investigative Team on U.S. Space Station Design (Keidanren), consisting of members of the Space Development Promotion Council and representatives of Japanese industries involved in Japan's space station development effort are presented. This team visited NASA facilities in February, 1985. The objectives of the study team are to gather information on preliminary design efforts toward space station planning in Japan and the promotion of Japanese space related industries, as well as the evaluation of the present status of space environment exploitation in the U.S. This report is intended to be a basic reference for government agencies and industry in addressing the course of action to be taken in the future development of Japan's space station participation.

Severe Accident Test Station Design Document

DOE Office of Scientific and Technical Information (OSTI.GOV)

Snead, Mary A.; Yan, Yong; Howell, Michael

The purpose of the ORNL severe accident test station (SATS) is to provide a platform for evaluation of advanced fuels under projected beyond design basis accident (BDBA) conditions. The SATS delivers the capability to map the behavior of advanced fuels concepts under accident scenarios across various temperature and pressure profiles, steam and steam-hydrogen gas mixtures, and thermal shock. The overall facility will include parallel capabilities for examination of fuels and irradiated materials (in-cell) and non-irradiated materials (out-of-cell) at BDBA conditions as well as design basis accident (DBA) or loss of coolant accident (LOCA) conditions. Also, a supporting analytical infrastructure tomore » provide the data-needs for the fuel-modeling components of the Fuel Cycle Research and Development (FCRD) program will be put in place in a parallel manner. This design report contains the information for the first, second and third phases of design and construction of the SATS. The first phase consisted of the design and construction of an out-of-cell BDBA module intended for examination of non-irradiated materials. The second phase of this work was to construct the BDBA in-cell module to test irradiated fuels and materials as well as the module for DBA (i.e. LOCA) testing out-of-cell, The third phase was to build the in-cell DBA module. The details of the design constraints and requirements for the in-cell facility have been closely captured during the deployment of the out-of-cell SATS modules to ensure effective future implementation of the in-cell modules.« less

Design Development of a Combined Deployment and Pointing System for the International Space Station Neutron Star Interior Composition Explorer Telescope

NASA Technical Reports Server (NTRS)

Budinoff, Jason; Gendreau, Keith; Arzoumanian, Zaven; Baker, Charles; Berning, Robert; Colangelo, Todd; Holzinger, John; Lewis, Jesse; Liu, Alice; Mitchell, Alissa;

Design Development of a Combined Deployment and Pointing System for the International Space Station Neutron Star Interior Composition Explorer Telescope

NASA Technical Reports Server (NTRS)

Budinoff, Jason; Gendreau, Keith; Arzoumanian, Zaven; Baker, Charles; Berning, Robert; Colangelo, TOdd; Holzinger, John; Lewis, Jesse; Liu, Alice; Mitchell, Alissa;

Bioengineering Strategies for Designing Targeted Cancer Therapies

PubMed Central

Wen, Xuejun

2014-01-01

The goals of bioengineering strategies for targeted cancer therapies are (1) to deliver a high dose of an anticancer drug directly to a cancer tumor, (2) to enhance drug uptake by malignant cells, and (3) to minimize drug uptake by nonmalignant cells. Effective cancer-targeting therapies will require both passive- and active targeting strategies and a thorough understanding of physiologic barriers to targeted drug delivery. Designing a targeted therapy includes the selection and optimization of a nanoparticle delivery vehicle for passive accumulation in tumors, a targeting moiety for active receptor-mediated uptake, and stimuli-responsive polymers for control of drug release. The future direction of cancer targeting is a combinatorial approach, in which targeting therapies are designed to use multiple targeting strategies. The combinatorial approach will enable combination therapy for delivery of multiple drugs and dual ligand targeting to improve targeting specificity. Targeted cancer treatments in development and the new combinatorial approaches show promise for improving targeted anticancer drug delivery and improving treatment outcomes. PMID:23768509

Design of an ammonia two-phase Prototype Thermal Bus for Space Station

NASA Technical Reports Server (NTRS)

Brown, Richard F.; Gustafson, Eric; Parish, Richard

1987-01-01

The feasibility of two-phase heat transport systems for use on Space Station was demonstrated by testing the Thermal Bus Technology Demonstrator (TBTD) as part of the Integrated Two-Phase System Test in NASA-JSC's Thermal Test Bed. Under contract to NASA-JSC, Grumman is currently developing the successor to the TBTD, the Prototype Thermal Bus System (TBS). The TBS design, which uses ammonia as the working fluid, is intended to achieve a higher fidelity level than the TBTD by incorporating both improvements based on TBTD testing and realistic design margins, and by addressing Space Station issues such as redundancy and maintenance. The TBS is currently being fabricated, with testing scheduled for late 1987/early 1988. This paper describes the TBS design which features fully redundant plumbing loops, five evaporators designed to represent different heat acquisition interfaces, 14 condensers which mate with either space radiators or facility heat exchangers, and several modular components.

Using computer graphics to design Space Station Freedom viewing

NASA Technical Reports Server (NTRS)

Goldsberry, B. S.; Lippert, B. O.; Mckee, S. D.; Lewis, J. L., Jr.; Mount, F. E.

1989-01-01

An important aspect of planning for Space Station Freedom at the United States National Aeronautics and Space Administration (NASA) is the placement of the viewing windows and cameras for optimum crewmember use. Researchers and analysts are evaluating the placement options using a three-dimensional graphics program called PLAID. This program, developed at the NASA Johnson Space Center (JSC), is being used to determine the extent to which the viewing requirements for assembly and operations are being met. A variety of window placement options in specific modules are assessed for accessibility. In addition, window and camera placements are analyzed to insure that viewing areas are not obstructed by the truss assemblies, externally-mounted payloads, or any other station element. Other factors being examined include anthropometric design considerations, workstation interfaces, structural issues, and mechanical elements.

Conceptual moderator studies for the Spallation Neutron Source short-pulse second target station

DOE PAGES

Gallmeier, F. X.; Lu, W.; Riemer, B. W.; ...

2016-06-14

We identified candidate moderator configurations for a short-pulse second target station (STS) at the Oak Ridge National Laboratory Spallation Neutron Source (SNS) using a global optimizer framework built around the MCNPX particle transport code. Neutron brightness metrics were selected as the figure-of-merit. We assumed that STS would use one out of six proton pulses produced by an SNS accelerator upgraded to operate at 1.3 GeV proton energy, 2.8 MW power and 60 Hz repetition rate. The simulations indicate that the peak brightness can be increased by a factor of 5 and 2.5 on a per proton pulse basis compared tomore » the SNS first target station for both coupled and decoupled para-hydrogen moderators, respectively. Additional increases by factors of 3 and 2 were demonstrated for coupled and decoupled moderators, respectively, by reducing the area of neutron emission from 100 × 100 mm 2 to 20 × 20 mm 2. Furthermore, this increase in brightness has the potential to translate to an increase of beam intensity at the instruments’ sample positions even though the total neutron emission of the smaller moderator is less than that of the larger. This is especially true for instruments with small samples (beam dimensions). The increased fluxes in the STS moderators come at accelerated poison and de-coupler burnout and higher radiation-induced material damage rates per unit power, which overall translate into lower moderator lifetimes. Our first effort decoupled group moderators into a cluster collectively positioning them at the peak neutron production zone in the target and having a three-port neutron emission scheme that complements that of a cylindrical coupled moderator.« less

Conceptual moderator studies for the Spallation Neutron Source short-pulse second target station

NASA Astrophysics Data System (ADS)

Gallmeier, F. X.; Lu, W.; Riemer, B. W.; Zhao, J. K.; Herwig, K. W.; Robertson, J. L.

2016-06-01

Candidate moderator configurations for a short-pulse second target station (STS) at the Oak Ridge National Laboratory Spallation Neutron Source (SNS) have been identified using a global optimizer framework built around the MCNPX particle transport code. Neutron brightness metrics were selected as the figure-of-merit. We assumed that STS would use one out of six proton pulses produced by an SNS accelerator upgraded to operate at 1.3 GeV proton energy, 2.8 MW power and 60 Hz repetition rate. The simulations indicate that the peak brightness can be increased by a factor of 5 and 2.5 on a per proton pulse basis compared to the SNS first target station for both coupled and decoupled para-hydrogen moderators, respectively. Additional increases by factors of 3 and 2 were demonstrated for coupled and decoupled moderators, respectively, by reducing the area of neutron emission from 100 × 100 mm2 to 20 × 20 mm2. This increase in brightness has the potential to translate to an increase of beam intensity at the instruments' sample positions even though the total neutron emission of the smaller moderator is less than that of the larger. This is especially true for instruments with small samples (beam dimensions). The increased fluxes in the STS moderators come at accelerated poison and de-coupler burnout and higher radiation-induced material damage rates per unit power, which overall translate into lower moderator lifetimes. A first effort was undertaken to group decoupled moderators into a cluster collectively positioning them at the peak neutron production zone in the target and having a three-port neutron emission scheme that complements that of a cylindrical coupled moderator.

Conceptual moderator studies for the Spallation Neutron Source short-pulse second target station

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gallmeier, F. X.; Lu, W.; Riemer, B. W.

We identified candidate moderator configurations for a short-pulse second target station (STS) at the Oak Ridge National Laboratory Spallation Neutron Source (SNS) using a global optimizer framework built around the MCNPX particle transport code. Neutron brightness metrics were selected as the figure-of-merit. We assumed that STS would use one out of six proton pulses produced by an SNS accelerator upgraded to operate at 1.3 GeV proton energy, 2.8 MW power and 60 Hz repetition rate. The simulations indicate that the peak brightness can be increased by a factor of 5 and 2.5 on a per proton pulse basis compared tomore » the SNS first target station for both coupled and decoupled para-hydrogen moderators, respectively. Additional increases by factors of 3 and 2 were demonstrated for coupled and decoupled moderators, respectively, by reducing the area of neutron emission from 100 × 100 mm 2 to 20 × 20 mm 2. Furthermore, this increase in brightness has the potential to translate to an increase of beam intensity at the instruments’ sample positions even though the total neutron emission of the smaller moderator is less than that of the larger. This is especially true for instruments with small samples (beam dimensions). The increased fluxes in the STS moderators come at accelerated poison and de-coupler burnout and higher radiation-induced material damage rates per unit power, which overall translate into lower moderator lifetimes. Our first effort decoupled group moderators into a cluster collectively positioning them at the peak neutron production zone in the target and having a three-port neutron emission scheme that complements that of a cylindrical coupled moderator.« less

Development of Space Station strut design

NASA Technical Reports Server (NTRS)

Johnson, R. R.; Bluck, R. M.; Holmes, A. M. C.; Kural, M. H.

1986-01-01

Candidate Space Station struts exhibiting high stiffness (38-40 msi modulus of elasticity) were manufactured and experimentally evaluated. One and two inch diameter aluminum-clad evaluation specimens were manufactured using a unique dry fiber resin injection process. Preliminary tests were performed on strut elements having 80 percent high-modulus graphite epoxy and 20 percent aluminum. Performed tests included modulus of elasticity, thermal cycling, and coefficient of thermal expansion. The paper describes the design approach, including an analytical assessment of strut thermal deformation behavior. The major thrust of this paper is the manufacturing process which produces aluminum-clad struts with precisely controlled properties which can be fine-tuned after fabrication. An impact test and evaluation procedure for evaluating toughness is described.

Conceptual design of the Space Station combustion module

NASA Technical Reports Server (NTRS)

Morilak, Daniel P.; Rohn, Dennis W.; Rhatigan, Jennifer L.

1994-01-01

The purpose of this paper is to describe the conceptual design of the Combustion Module for the International Space Station Alpha (ISSA). This module is part of the Space Station Fluids/Combustion Facility (SS FCF) under development at the NASA Lewis Research Center. The Fluids/Combustion Facility is one of several science facilities which are being developed to support microgravity science investigations in the US Laboratory Module of the ISSA. The SS FCF will support a multitude of fluids and combustion science investigations over the lifetime of the ISSA and return state-of-the-art science data in a timely and efficient manner to the scientific communities. This will be accomplished through modularization of hardware, with planned, periodic upgrades; modularization of like scientific investigations that make use of common facility functions; and through the use of orbital replacement units (ORU's) for incorporation of new technology and new functionality. The SS FCF is scheduled to become operational on-orbit in 1999. The Combustion Module is presently scheduled for launch to orbit and integration with the Fluids/Combustion Facility in 1999. The objectives of this paper are to describe the history of the Combustion Module concept, the types of combustion science investigations which will be accommodated by the module, the hardware design heritage, the hardware concept, and the hardware breadboarding efforts currently underway.

Conceptual Design of the Space Station Fluids Module

NASA Technical Reports Server (NTRS)

Rohn, Dennis W.; Morilak, Daniel P.; Rhatigan, Jennifer L.; Peterson, Todd T.

1994-01-01

The purpose of this paper is to describe the conceptual design of the Fluids Module for the International Space Station Alpha (ISSA). This module is part of the Space Station Fluids/Combustion Facility (SS FCF) under development at the NASA Lewis Research Center. The Fluids/Combustion Facility is one of several science facilities which are being developed to support microgravity science investigations in the US Laboratory Module of the ISSA. The SS FCF will support a multitude of fluids and combustion science investigations over the lifetime of the ISSA and return state-of-the-art science data in a timely and efficient manner to the scientific communities. This will be accomplished through modularization of hardware, with planned, periodic upgrades; modularization of like scientific investigations that make use of common facility functions; and use of orbital replacement units (ORU's) for incorporation of new technology and new functionality. Portions of the SS FCF are scheduled to become operational on-orbit in 1999. The Fluids Module is presently scheduled for launch to orbit and integration with the Fluids/Combustion Facility in 2001. The objectives of this paper are to describe the history of the Fluids Module concept, the types of fluids science investigations which will be accommodated by the module, the hardware design heritage, the hardware concept, and the hardware breadboarding efforts currently underway.

The Space Station air revitalization subsystem design concept

NASA Technical Reports Server (NTRS)

Ray, C. D.; Ogle, K. Y.; Tipps, R. W.; Carrasquillo, R. L.; Wieland, P.

1987-01-01

The current status of the Space Station (SS) Environmental Control and Life Support System (ECLSS) Air Revitalization Subsystem (ARS) design is outlined. ARS performance requirements are provided, along with subsystem options for each ARS function and selected evaluations of the relative merits of each subsystem. Detailed computer models that have been developed to analyze individual subsystem performance capabilities are also discussed. A summary of ARS subsystem level testing planned and completed by NASA Marshall Space Flight Center (MSFC) is given.

Preliminary space station solar array structural design study

NASA Technical Reports Server (NTRS)

Dorsey, J. T.; Bush, H. G.; Mikulas, M. M., Jr.

1984-01-01

Structurally efficient ways to support the large solar arrays (3,716 square meters which are currently considered for space station use) are examined. An erectable truss concept is presented for the on orbit construction of winged solar arrays. The means for future growth, maintenance, and repair are integrally designed into this concept. Results from parametric studies, which highlight the physical and structural differences between various configuration options are presented. Consideration is given to both solar blanket and hard panel arrays.

Preliminary space station solar array structural design study

NASA Astrophysics Data System (ADS)

Dorsey, J. T.; Bush, H. G.; Mikulas, M. M., Jr.

Structurally efficient ways to support the large solar arrays (3,716 square meters which are currently considered for space station use) are examined. An erectable truss concept is presented for the on orbit construction of winged solar arrays. The means for future growth, maintenance, and repair are integrally designed into this concept. Results from parametric studies, which highlight the physical and structural differences between various configuration options are presented. Consideration is given to both solar blanket and hard panel arrays.

Preliminary design of the Space Station environmental control and life support system

NASA Technical Reports Server (NTRS)

Reuter, J. L.; Turner, L. D.; Humphries, W. R.

1988-01-01

This paper outlines the current status of the Space Station Enrivonmental Control and Life Support System (ECLSS). The seven subsystem groups which comprise the ECLSS are identified and their functional descriptions are provided. The impact that the nominal and safe haven operating requirements have on the physical distribution, sizing, and number of ECLSS subsystems is described. The role that the major ECLSS interfaces with other Space Station systems and elements play in the ECLSS design is described.

Advanced EVA system design requirements study: EVAS/space station system interface requirements

NASA Technical Reports Server (NTRS)

Woods, T. G.

1985-01-01

The definition of the Extravehicular Activity (EVA) systems interface requirements and accomodations for effective integration of a production EVA capability into the space station are contained. A description of the EVA systems for which the space station must provide the various interfaces and accomodations are provided. The discussion and analyses of the various space station areas in which the EVA interfaces are required and/or from which implications for EVA system design requirements are derived, are included. The rationale is provided for all EVAS mechanical, fluid, electrical, communications, and data system interfaces as well as exterior and interior requirements necessary to facilitate EVA operations. Results of the studies supporting these discussions are presented in the appendix.

Practical design considerations for photovoltaic power station

NASA Astrophysics Data System (ADS)

Swanson, T. D.

Aspects of photovoltaic (PV) technology are discussed along with generic PV design considerations, taking into account the resource sunlight, PV modules and their reliability, questions of PV system design, the support structure subsystem, and a power conditioning unit subsystem. A description is presented of two recent projects which demonstrate the translation of an idea into actual working PV systems. A privately financed project in Denton, Maryland, went on line in early December, 1982, and began providing power to the local utility grid. It represents the first intermediate size, grid-connected, privately financed power station in the U.S. Based on firm quotes, the actual cost of this system is about $13/W peak. The other project, called the PV Breeder, is an energy independent facility which utilizes solar power to make new solar cells. It is also the first large industrial structure completely powered by the sun.

DESIGNING AN OPPORTUNITY FUEL WITH BIOMASS AND TIRE-DERIVED FUEL FOR COFIRING AT WILLOW ISLAND GENERATING STATION AND COFIRING SAWDUST WITH COAL AT ALBRIGHT GENERATING STATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

K. Payette; D. Tillman

During the period July 1, 2003-September 30, 2003, Allegheny Energy Supply Co., LLC (Allegheny) proceeded with demonstration operations at the Willow Island Generating Station and improvements to the Albright Generating Station cofiring systems. The demonstration operations at Willow Island were designed to document integration of bio mass cofiring into commercial operations, including evaluating new sources of biomass supply. The Albright improvements were designed to increase the resource base for the projects, and to address issues that came up during the first year of operations. During this period, a major presentation summarizing the program was presented at the Pittsburgh Coal Conference.more » This report summarizes the activities associated with the Designer Opportunity Fuel program, and demonstrations at Willow Island and Albright Generating Stations.« less

A New Design of Seismic Stations Deployed in South Tyrol

NASA Astrophysics Data System (ADS)

Melichar, P.; Horn, N.

2007-05-01

When designing the seismic network in South Tyrol, the seismic service of Austria and the Civil defense in South Tyrol combined more that 10 years experience in running seismic networks and private communication systems. In recent years the high data return rate of > 99% and network uptime of > 99.% is achieved by the combination of high quality station design and equipment, and the use of the Antelope data acquisition and processing software which comes with suite of network monitoring & alerting tools including Nagios, etc. The new Data Center is located in city of Bolzano and is connected to the other Data Centers in Austria, Switzerland, and Italy for data back up purposes. Each Data Center uses also redundant communication system if the primary system fails. When designing the South Tyrol network, new improvements were made in seismometer installations, grounding, lighting protection and data communications in order to improve quality of data recorded as well as network up-time, and data return. The new 12 stations are equipped with 6 Channels Q330+PB14f connected to STS2 + EpiSensor sensor. One of the key achievements was made in the grounding concept for the whole seismic station - and aluminum boxes were introduced which delivered Faraday cage isolation. Lightning protection devices are used for the equipment inside the aluminum housing where seismometer and data logger are housed. For the seismometer cables a special shielding was introduced. The broadband seismometer and strong-motion sensor are placed on a thick glass plate and therefore isolated from the ground. The precise seismometer orientation was done by a special groove on the glass plate and in case of a strong earthquake; the seismometer is tide up to the base plate. Temperature stability was achieved by styrofoam sheets inside the seismometer aluminum protection box.

Space station Simulation Computer System (SCS) study for NASA/MSFC. Volume 4: Conceptual design report

NASA Technical Reports Server (NTRS)

1989-01-01

The Simulation Computer System (SCS) is the computer hardware, software, and workstations that will support the Payload Training Complex (PTC) at Marshall Space Flight Center (MSFC). The PTC will train the space station payload scientists, station scientists, and ground controllers to operate the wide variety of experiments that will be onboard the Space Station Freedom. In the first step of this task, a methodology was developed to ensure that all relevant design dimensions were addressed, and that all feasible designs could be considered. The development effort yielded the following method for generating and comparing designs in task 4: (1) Extract SCS system requirements (functions) from the system specification; (2) Develop design evaluation criteria; (3) Identify system architectural dimensions relevant to SCS system designs; (4) Develop conceptual designs based on the system requirements and architectural dimensions identified in step 1 and step 3 above; (5) Evaluate the designs with respect to the design evaluation criteria developed in step 2 above. The results of the method detailed in the above 5 steps are discussed. The results of the task 4 work provide the set of designs which two or three candidate designs are to be selected by MSFC as input to task 5-refine SCS conceptual designs. The designs selected for refinement will be developed to a lower level of detail, and further analyses will be done to begin to determine the size and speed of the components required to implement these designs.

Conceptual moderator studies for the Spallation Neutron Source short-pulse second target station

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gallmeier, F. X., E-mail: gallmeierfz@ornl.gov; Lu, W.; Riemer, B. W.

Candidate moderator configurations for a short-pulse second target station (STS) at the Oak Ridge National Laboratory Spallation Neutron Source (SNS) have been identified using a global optimizer framework built around the MCNPX particle transport code. Neutron brightness metrics were selected as the figure-of-merit. We assumed that STS would use one out of six proton pulses produced by an SNS accelerator upgraded to operate at 1.3 GeV proton energy, 2.8 MW power and 60 Hz repetition rate. The simulations indicate that the peak brightness can be increased by a factor of 5 and 2.5 on a per proton pulse basis comparedmore » to the SNS first target station for both coupled and decoupled para-hydrogen moderators, respectively. Additional increases by factors of 3 and 2 were demonstrated for coupled and decoupled moderators, respectively, by reducing the area of neutron emission from 100 × 100 mm{sup 2} to 20 × 20 mm{sup 2}. This increase in brightness has the potential to translate to an increase of beam intensity at the instruments’ sample positions even though the total neutron emission of the smaller moderator is less than that of the larger. This is especially true for instruments with small samples (beam dimensions). The increased fluxes in the STS moderators come at accelerated poison and de-coupler burnout and higher radiation-induced material damage rates per unit power, which overall translate into lower moderator lifetimes. A first effort was undertaken to group decoupled moderators into a cluster collectively positioning them at the peak neutron production zone in the target and having a three-port neutron emission scheme that complements that of a cylindrical coupled moderator.« less

Modular space station phase B extension preliminary system design. Volume 7: Ancillary studies

NASA Technical Reports Server (NTRS)

Jones, A. L.

1972-01-01

Sortie mission analysis and reduced payloads size impact studies are presented. In the sortie mission analysis, a modular space station oriented experiment program to be flown by the space shuttle during the period prior to space station IOC is discussed. Experiments are grouped into experiment packages. Mission payloads are derived by grouping experiment packages and by adding support subsystems and structure. The operational and subsystems analyses of these payloads are described. Requirements, concepts, and shuttle interfaces are integrated. The sortie module/station module commonality and a sortie laboratory concept are described. In the payloads size analysis, the effect on the modular space station concept of reduced diameter and reduced length of the shuttle cargo bay is discussed. Design concepts are presented for reduced sizes of 12 by 60 ft, 14 by 40 ft, and 12 by 40 ft. Comparisons of these concepts with the modular station (14 by 60 ft) are made to show the impact of payload size changes.

BOILING NUCLEAR SUPERHEATER (BONUS) POWER STATION. Final Summary Design Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1962-05-01

The design and construction of the Boiling Nuclear Superheater (BONUS) Power Station at Punta Higuera on the seacoast at the westernmost tip of Puerto Rico are described. The reactor has an output of 17.5 Mw(e). This report will serve as a source of information for personnel engaged in management, evaluation, and training. (N.W.R.)

LBNF 1.2 MW Target: Conceptual Design & Fabrication

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crowley, C.; Ammigan, K.; Anderson, K.

2015-06-01

Fermilab’s Long-Baseline Neutrino Facility (LBNF) will utilize a modified design based on the NuMI low energy target that is reconfigured to accommodate beam operation at 1.2 MW. Achieving this power with a graphite target material and ancillary systems originally rated for 400 kW requires several design changes and R&D efforts related to material bonding and electrical isolation. Target cooling, structural design, and fabrication techniques must address higher stresses and heat loads that will be present during 1.2 MW operation, as the assembly will be subject to cyclic loads and thermal expansion. Mitigations must be balanced against compromises in neutrino yield.more » Beam monitoring and subsystem instrumentation will be updated and added to ensure confidence in target positioning and monitoring. Remote connection to the target hall support structure must provide for the eventual upgrade to a 2.4 MW target design, without producing excessive radioactive waste or unreasonable exposure to technicians during reconfiguration. Current designs and assembly layouts will be presented, in addition to current findings on processes and possibilities for prototype and final assembly fabrication.« less

LBNF 1.2 MW TARGET: CONCEPTUAL DESIGN & FABRICATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crowley, Cory F.; Ammigan, K.; Anderson, K.

2015-06-29

Fermilab’s Long-Baseline Neutrino Facility (LBNF) will utilize a modified design based on the NuMI low energy target that is reconfigured to accommodate beam operation at 1.2 MW. Achieving this power with a graphite target material and ancillary systems originally rated for 400 kW requires several design changes and R&D efforts related to material bonding and electrical isolation. Target cooling, structural design, and fabrication techniques must address higher stresses and heat loads that will be present during 1.2 MW operation, as the assembly will be subject to cyclic loads and thermal expansion. Mitigations must be balanced against compromises in neutrino yield.more » Beam monitoring and subsystem instrumentation will be updated and added to ensure confidence in target positioning and monitoring. Remote connection to the target hall support structure must provide for the eventual upgrade to a 2.4 MW target design, without producing excessive radioactive waste or unreasonable exposure to technicians during reconfiguration. Current designs and assembly layouts will be presented, in addition to current findings on processes and possibilities for prototype and final assembly fabrication.« less

Space Station Freedom photovoltaic power module design status

NASA Technical Reports Server (NTRS)

Jimenez, Amador P.; Hoberecht, Mark A.

1989-01-01

Electric power generation for the Space Station Freedom will be provided by four photovoltaic (PV) power modules using silicon solar cells during phase I operation. Each PV power module requires two solar arrays with 32,800 solar cells generating 18.75 kW of dc power for a total of 75 kW. A portion of this power will be stored in nickel-hydrogen batteries for use during eclipse, and the balance will be processed and converted to 20 kHz ac power for distribution to end users through the power management and distribution system. The design incorporates an optimized thermal control system, pointing and tracking provision with the application of gimbals, and the use of orbital replacement units to achieve modularization. The design status of the PV power module, as derived from major trade studies, is discussed at hardware levels ranging from component to system. Details of the design are presented where appropriate.

Space Station Freedom photovoltaic power module design status

NASA Technical Reports Server (NTRS)

Jimenez, Amador P.; Hoberecht, Mark A.

1989-01-01

Electric power generation for Space Station Freedom will be provided by four photovoltaic (PV) power modules using silicon solar cells during Phase 1 operation. Each PV power module requires two solar arrays with 32,800 solar cells generating 18.75 kW of dc power for a total of 75 kW. A portion of this power will be stored in nickel-hydrogen batteries for use during eclipse, and the balance will be processed and converted to 20 kHz ac power for distribution to end users through the power management and distribution system. The design incorporates an optimized thermal control system, pointing and tracking provision with the application of gimbals, and the use of orbital replacement units (ORU's) to achieve modularization. Design status of the PV power module, as derived from major trade studies, is discussed at hardware levels ranging from component to system. Details of the design are presented where appropriate.

DESIGNING AN OPPORTUNITY FUEL WITH BIOMASS AND TIRE-DERIVED FUEL FOR COFIRING AT WILLOW ISLAND GENERATING STATION AND COFIRING SAWDUST WITH COAL AT ALBRIGHT GENERATING STATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

K. Payette; D. Tillman

During the period January 1, 2003--March 31, 2003, Allegheny Energy Supply Co., LLC (Allegheny) proceeded with improvements to both the Willow Island and Albright Generating Station cofiring systems. These improvements were designed to increase the resource base for the projects, and to address issues that came up during the first year of operations. This report summarizes the activities associated with the Designer Opportunity Fuel program, and demonstrations at Willow Island and Albright Generating Stations.

International Space Station Remote Sensing Pointing Analysis

NASA Technical Reports Server (NTRS)

Jacobson, Craig A.

2007-01-01

This paper analyzes the geometric and disturbance aspects of utilizing the International Space Station for remote sensing of earth targets. The proposed instrument (in prototype development) is SHORE (Station High-Performance Ocean Research Experiment), a multiband optical spectrometer with 15 m pixel resolution. The analysis investigates the contribution of the error effects to the quality of data collected by the instrument. This analysis supported the preliminary studies to determine feasibility of utilizing the International Space Station as an observing platform for a SHORE type of instrument. Rigorous analyses will be performed if a SHORE flight program is initiated. The analysis begins with the discussion of the coordinate systems involved and then conversion from the target coordinate system to the instrument coordinate system. Next the geometry of remote observations from the Space Station is investigated including the effects of the instrument location in Space Station and the effects of the line of sight to the target. The disturbance and error environment on Space Station is discussed covering factors contributing to drift and jitter, accuracy of pointing data and target and instrument accuracies.

Enclosed versus open nursing stations in adult acute care psychiatric settings: does the design affect the therapeutic milieu?

PubMed

Southard, Kelly; Jarrell, Ashley; Shattell, Mona M; McCoy, Thomas P; Bartlett, Robin; Judge, Christine A

2012-05-01

Specific efforts by hospital accreditation organizations encourage renovation of nursing stations, so nurses can better see, attend, and care for their patients. The purpose of this study was to examine the effect of nursing station design on the therapeutic milieu in an adult acute care psychiatric unit. A repeated cross-sectional, pretest-posttest design was used. Data were collected from a convenience sample of 81 patients and 25 nursing staff members who completed the Ward Atmosphere Scale. Pretest data were collected when the unit had an enclosed nursing station, and posttest data were collected after renovations to the unit created an open nursing station. No statistically significant differences were found in patient or staff perceptions of the therapeutic milieu. No increase in aggression toward staff was found, given patients' ease of access to the nursing station. More research is needed about the impact of unit design in acute care psychiatric settings. Copyright 2012, SLACK Incorporated.

A computer program to determine the possible daily release window for sky target experiments

NASA Technical Reports Server (NTRS)

Michaud, N. H.

1973-01-01

A computer program is presented which is designed to determine the daily release window for sky target experiments. Factors considered in the program include: (1) target illumination by the sun at release time and during the tracking period; (2) look angle elevation above local horizon from each tracking station to the target; (3) solar depression angle from the local horizon of each tracking station during the experimental period after target release; (4) lunar depression angle from the local horizon of each tracking station during the experimental period after target release; and (5) total sky background brightness as seen from each tracking station while viewing the target. Program output is produced in both graphic and data form. Output data can be plotted for a single calendar month or year. The numerical values used to generate the plots are furnished to permit a more detailed review of the computed daily release windows.

Design of a Covert RFID Tag Network for Target Discovery and Target Information Routing

PubMed Central

Pan, Qihe; Narayanan, Ram M.

2011-01-01

Radio frequency identification (RFID) tags are small electronic devices working in the radio frequency range. They use wireless radio communications to automatically identify objects or people without the need for line-of-sight or contact, and are widely used in inventory tracking, object location, environmental monitoring. This paper presents a design of a covert RFID tag network for target discovery and target information routing. In the design, a static or very slowly moving target in the field of RFID tags transmits a distinct pseudo-noise signal, and the RFID tags in the network collect the target information and route it to the command center. A map of each RFID tag’s location is saved at command center, which can determine where a RFID tag is located based on each RFID tag’s ID. We propose the target information collection method with target association and clustering, and we also propose the information routing algorithm within the RFID tag network. The design and operation of the proposed algorithms are illustrated through examples. Simulation results demonstrate the effectiveness of the design. PMID:22163693

Design of a covert RFID tag network for target discovery and target information routing.

PubMed

Pan, Qihe; Narayanan, Ram M

2011-01-01

Radio frequency identification (RFID) tags are small electronic devices working in the radio frequency range. They use wireless radio communications to automatically identify objects or people without the need for line-of-sight or contact, and are widely used in inventory tracking, object location, environmental monitoring. This paper presents a design of a covert RFID tag network for target discovery and target information routing. In the design, a static or very slowly moving target in the field of RFID tags transmits a distinct pseudo-noise signal, and the RFID tags in the network collect the target information and route it to the command center. A map of each RFID tag's location is saved at command center, which can determine where a RFID tag is located based on each RFID tag's ID. We propose the target information collection method with target association and clustering, and we also propose the information routing algorithm within the RFID tag network. The design and operation of the proposed algorithms are illustrated through examples. Simulation results demonstrate the effectiveness of the design.

Mechanical design of a low concentration ratio solar array for a space station application

NASA Technical Reports Server (NTRS)

Biss, M. S.; Hsu, L.

1983-01-01

This paper describes a preliminary study and conceptual design of a low concentration ratio solar array for a space station application with approximately a 100 kW power requirement. The baseline design calls for a multiple series of inverted, truncated, pyramidal optical elements with a geometric concentration ratio (GCR) of 6. It also calls for low life cycle cost, simple on-orbit maintainability, 1984 technology readiness date, and gallium arsenide (GaAs) of silicon (Si) solar cell interchangeability. Due to the large area needed to produce the amount of power required for the baseline space station, a symmetrical wing design, making maximum use of the commonality of parts approach, was taken. This paper will describe the mechanical and structural design of a mass-producible solar array that is very easy to tailor to the needs of the individual user requirement.

From 2001 to 1994: Political environment and the design of NASA's Space Station system

NASA Technical Reports Server (NTRS)

Fries, Sylvia Doughty

1988-01-01

The U.S. civilian space station, a hope of numerous NASA engineers since before the agency was founded in 1958 and promoted by NASA as the country's 'next logical step' into space, provides an excellent case study of the way public-sector research and development agencies continuously redefine new technologies in the absence of the market discipline that governs private-sector technological development. The number of space station design studies conducted since 1959, both internally by NASA or contracted by the agency to the aerospace industry, easily exceeds a hundred. Because of this, three clearly distinguishable examples are selected from the almost thirty-year history of space station design in NASA. Together these examples illustrate the difficulty of defining a new technological system in the public sector as that system becomes increasingly subject, for its development, to the vagaries of federal research and development politics.

Design and testing of the Space Station Freedom Propellant Tank Assembly

NASA Technical Reports Server (NTRS)

Dudley, D. D.; Thonet, T. A.; Goforth, A. M.

1992-01-01

Propellant storage and management functions for the Propulsion Module of the U.S. Space Station Freedom are provided by the Propellant Tank Assembly (PTA). The PTA consists of a surface-tension type propellant acquisition device contained within a welded titanium pressure vessel. The PTA design concept was selected with high reliability and low program risk as primary goals in order to meet stringent NASA structural, expulsion, fracture control and reliability requirements. The PTA design makes use of Shuttle Orbital Maneuvering System and Peacekeeper Propellant Storage Assembly design and analysis techniques. This paper summarizes the PTA design solution and discusses the underlying detailed analyses. In addition, design verification and qualification test activities are discussed.

Life support and internal thermal control system design for the Space Station Freedom

NASA Technical Reports Server (NTRS)

Humphries, R.; Mitchell, K.; Reuter, J.; Carrasquillo, R.; Beverly, B.

1991-01-01

A Review of the Space Station Freedom Environmental Control and Life Support System (ECLSS) as well as the Internal Thermal Control System (ITCS) design, including recent changes resulting from an activity to restructure the program, is provided. The development state of the original Space Station Freedom ECLSS through the restructured configuration is considered and the selection of regenerative subsystems for oxygen and water reclamation is addressed. A survey of the present ground development and verification program is given.

The use of multidimensional scaling for facilities layout - An application to the design of the Space Station

NASA Technical Reports Server (NTRS)

Tullis, Thomas S.; Bied Sperling, Barbra; Steinberg, A. L.

1986-01-01

Before an optimum layout of the facilities for the proposed Space Station can be designed, it is necessary to understand the functions that will be performed by the Space Station crew and the relationships among those functions. Five criteria for assessing functional relationships were identified. For each of these criteria, a matrix representing the degree of association of all pairs of functions was developed. The key to making inferences about the layout of the Space Station from these matrices was the use of multidimensional scaling (MDS). Applying MDS to these matrices resulted in spatial configurations of the crew functions in which smaller distances in the MDS configuration reflected closer associations. An MDS analysis of a composite matrix formed by combining the five individual matrices resulted in two dimensions that describe the configuration: a 'private-public' dimension and a 'group-individual' dimension. Seven specific recommendations for Space Station layout were derived from analyses of the MDS configurations. Although these techniques have been applied to the design of the Space Station, they can be applied to the design of any facility where people live or work.

76 FR 40345 - Information on Surplus Land at a Military Installation Designated for Disposal: Naval Station...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-08

... Installation Designated for Disposal: Naval Station Pascagoula, Mississippi AGENCY: Department of the Navy, DoD. ACTION: Notice. SUMMARY: This notice provides information on withdrawal of surplus property at Naval... 29405, telephone 843-743-2147. SUPPLEMENTARY INFORMATION: In 2005, Naval Station Pascagoula, including...

Issues in the design of an executive controller shell for Space Station automation

NASA Technical Reports Server (NTRS)

Erickson, William K.; Cheeseman, Peter C.

1986-01-01

A major goal of NASA's Systems Autonomy Demonstration Project is to focus research in artificial intelligence, human factors, and dynamic control systems in support of Space Station automation. Another goal is to demonstrate the use of these technologies in real space systems, for both round-based mission support and on-board operations. The design, construction, and evaluation of an intelligent autonomous system shell is recognized as an important part of the Systems Autonomy research program. His paper describes autonomous systems and executive controllers, outlines how these intelligent systems can be utilized within the Space Station, and discusses a number of key design issues that have been raised during some preliminary work to develop an autonomous executive controller shell at NASA Ames Research Center.

Exploration-Related Research on the International Space Station: Connecting Science Results to the Design of Future Missions

NASA Technical Reports Server (NTRS)

Rhatigan, Jennifer L.; Robinson, Julie A.; Sawin, Charles F.; Ahlf, Peter R.

2005-01-01

In January, 2004, the US President announced a vision for space exploration, and charged NASA with utilizing the International Space Station (ISS) for research and technology targeted at supporting the US space exploration goals. This paper describes: 1) what we have learned from the first four years of research on ISS relative to the exploration mission, 2) the on-going research being conducted in this regard, 3) our current understanding of the major exploration mission risks that the ISS can be used to address, and 4) current progress in realigning NASA s research portfolio for ISS to support exploration missions. Specifically, we discuss the focus of research on solving the perplexing problems of maintaining human health on long-duration missions, and the development of countermeasures to protect humans from the space environment, enabling long duration exploration missions. The interchange between mission design and research needs is dynamic, where design decisions influence the type of research needed, and results of research influence design decisions. The fundamental challenge to science on ISS is completing experiments that answer key questions in time to shape design decisions for future exploration. In this context, exploration-relevant research must do more than be conceptually connected to design decisions-it must become a part of the mission design process.

Implications of privacy needs and interpersonal distancing mechanisms for space station design

NASA Technical Reports Server (NTRS)

Harrison, Albert A.; Sommer, Robert; Struthers, Nancy; Hoyt, Kathleen

1988-01-01

Isolation, confinement, and the characteristics of microgravity will accentuate the need for privacy in the proposed NASA space station, yet limit the mechanism available for achieving it. This study proposes a quantitative model for understanding privacy, interpersonal distancing, and performance, and discusses the practical implications for Space Station design. A review of the relevant literature provided the basis for a database, definitions of physical and psychological distancing, loneliness, and crowding, and a quantitative model of situational privacy. The model defines situational privacy (the match between environment and task), and focuses on interpersonal contact along visual, auditory, olfactory, and tactile dimensions. It involves summing across pairs of crew members, contact dimensions, and time, yet also permits separate analyses of subsets of crew members and contact dimensions. The study concludes that performance will benefit when the type and level of contact afforded by the environment align with that required by the task. The key to achieving this is to design a flexible, definable, and redefinable interior environment that provides occupants with a wide array of options to meet their needs for solitude, limited social interaction, and open group activity. The report presents 49 recommendations in five categories to promote a wide range of privacy options despite the space station's volumetric limitations.

Virtual workstations and telepresence interfaces: Design accommodations and prototypes for Space Station Freedom evolution

NASA Technical Reports Server (NTRS)

Mcgreevy, Michael W.

1990-01-01

An advanced human-system interface is being developed for evolutionary Space Station Freedom as part of the NASA Office of Space Station (OSS) Advanced Development Program. The human-system interface is based on body-pointed display and control devices. The project will identify and document the design accommodations ('hooks and scars') required to support virtual workstations and telepresence interfaces, and prototype interface systems will be built, evaluated, and refined. The project is a joint enterprise of Marquette University, Astronautics Corporation of America (ACA), and NASA's ARC. The project team is working with NASA's JSC and McDonnell Douglas Astronautics Company (the Work Package contractor) to ensure that the project is consistent with space station user requirements and program constraints. Documentation describing design accommodations and tradeoffs will be provided to OSS, JSC, and McDonnell Douglas, and prototype interface devices will be delivered to ARC and JSC. ACA intends to commercialize derivatives of the interface for use with computer systems developed for scientific visualization and system simulation.

Considerations for a design and operations knowledge support system for Space Station Freedom

NASA Technical Reports Server (NTRS)

Erickson, Jon D.; Crouse, Kenneth H.; Wechsler, Donald B.; Flaherty, Douglas R.

1989-01-01

Engineering and operations of modern engineered systems depend critically upon detailed design and operations knowledge that is accurate and authoritative. A design and operations knowledge support system (DOKSS) is a modern computer-based information system providing knowledge about the creation, evolution, and growth of an engineered system. The purpose of a DOKSS is to provide convenient and effective access to this multifaceted information. The complexity of Space Station Freedom's (SSF's) systems, elements, interfaces, and organizations makes convenient access to design knowledge especially important, when compared to simpler systems. The life cycle length, being 30 or more years, adds a new dimension to space operations, maintenance, and evolution. Provided here is a review and discussion of design knowledge support systems to be delivered and operated as a critical part of the engineered system. A concept of a DOKSS for Space Station Freedom (SSF) is presented. This is followed by a detailed discussion of a DOKSS for the Lyndon B. Johnson Space Center and Work Package-2 portions of SSF.

Implications of Privacy Needs and Interpersonal Distancing Mechanisms for Space Station Design

NASA Technical Reports Server (NTRS)

Harrison, A. A.; Sommer, R.; Struthers, N.; Hoyt, K.

1986-01-01

The literature on privacy needs, personal space, interpersonal distancing, and crowding is reveiwed with special reference to spaceflight and spaceflight analogous conditions. A quantitative model is proposed for understanding privacy, interpersonal distancing, and performance. The implications for space station design is described.

Analytical determination of space station response to crew motion and design of suspension system for microgravity experiments

NASA Technical Reports Server (NTRS)

Liu, F. C.

1986-01-01

The objective of this investigation is to make analytical determination of the acceleration produced by crew motion in an orbiting space station and define design parameters for the suspension system of microgravity experiments. A simple structural model for simulation of the IOC space station is proposed. Mathematical formulation of this model provides the engineers a simple and direct tool for designing an effective suspension system.

49 CFR 37.49 - Designation of responsible person(s) for intercity and commuter rail stations.

Code of Federal Regulations, 2013 CFR

2013-10-01

...) designated in accordance with this section shall bear the legal and financial responsibility for making a key... party. (c) In the case of a station more than fifty percent of which is owned by a private entity the... of which no entity owns more than fifty percent, the owners of the station (other than private entity...

49 CFR 37.49 - Designation of responsible person(s) for intercity and commuter rail stations.

Code of Federal Regulations, 2012 CFR

2012-10-01

...) designated in accordance with this section shall bear the legal and financial responsibility for making a key... party. (c) In the case of a station more than fifty percent of which is owned by a private entity the... of which no entity owns more than fifty percent, the owners of the station (other than private entity...

49 CFR 37.49 - Designation of responsible person(s) for intercity and commuter rail stations.

Code of Federal Regulations, 2014 CFR

2014-10-01

...) designated in accordance with this section shall bear the legal and financial responsibility for making a key... party. (c) In the case of a station more than fifty percent of which is owned by a private entity the... of which no entity owns more than fifty percent, the owners of the station (other than private entity...

49 CFR 37.49 - Designation of responsible person(s) for intercity and commuter rail stations.

Code of Federal Regulations, 2011 CFR

2011-10-01

...) designated in accordance with this section shall bear the legal and financial responsibility for making a key... party. (c) In the case of a station more than fifty percent of which is owned by a private entity the... of which no entity owns more than fifty percent, the owners of the station (other than private entity...

Unhealthful Food-and-Beverage Advertising in Subway Stations: Targeted Marketing, Vulnerable Groups, Dietary Intake, and Poor Health.

PubMed

Lucan, Sean C; Maroko, Andrew R; Sanon, Omar C; Schechter, Clyde B

2017-04-01

Unhealthful food-and-beverage advertising often targets vulnerable groups. The extent of such advertising in subway stations has not been reported and it is not clear how ad placement may relate to subway ridership or community demographics, or what the implications might be for diets and diet-related health in surrounding communities. Riding all subway lines (n = 7) in the Bronx, NY, USA, investigators systematically assessed all print ads (n = 1586) in all stations (n = 68) in 2012. Data about subway ridership came from the Metropolitan Transportation Authority. Demographic data on surrounding residential areas came from the U.S. Census Bureau. Data on dietary intake and diet-related conditions came from a city health-department survey. There were no ads promoting "more-healthful" food-or-beverage items (i.e., fruits, vegetables, whole grains, nuts, water or milk). There were many ads for "less-healthful" items (e.g., candies, chips, sugary cereals, frozen pizzas, "energy" drinks, coffee confections, hard alcohol, and beer). Ad placement did not relate to the number of riders entering at stations. Instead, exposure to food-or-beverage ads generally, and to "less-healthful" ads particularly (specifically ads in Spanish, directed at youth, and/or featuring minorities), was directly correlated with poverty, lower high-school graduation rates, higher percentages of Hispanics, and/or higher percentages of children in surrounding residential areas. Correlations were robust to sensitivity analyses. Additional analyses suggested correlations between ad exposures and sugary-drink consumption, fruit-and-vegetable intake, and diabetes, hypertension, and high-cholesterol rates. Subway-station ads for "less-healthful" items were located disproportionately in areas home to vulnerable populations facing diet and diet-related-health challenges. The fact that uneven ad placement did not relate to total rider counts suggests ads were not directed at the largest

Natural environment design criteria for the space station program definition phase

NASA Technical Reports Server (NTRS)

Vaughan, W. W.

1984-01-01

The natural environment design criteria requirements for use in the Space Station and its Elements (SSPE) definition phase studies are presented. The atmospheric dynamic and thermodynamic environments, meteoroids, radiation, physical constants are addressed. It is intended to enable all groups involved in the definition phase studies to proceed with a common and consistent set of natural environment criteria requirements.

Space station integrated wall design and penetration damage control

NASA Technical Reports Server (NTRS)

Coronado, A. R.; Gibbins, M. N.; Wright, M. A.; Stern, P. H.

1987-01-01

The analysis code BUMPER executes a numerical solution to the problem of calculating the probability of no penetration (PNP) of a spacecraft subject to man-made orbital debris or meteoroid impact. The codes were developed on a DEC VAX 11/780 computer that uses the Virtual Memory System (VMS) operating system, which is written in FORTRAN 77 with no VAX extensions. To help illustrate the steps involved, a single sample analysis is performed. The example used is the space station reference configuration. The finite element model (FEM) of this configuration is relatively complex but demonstrates many BUMPER features. The computer tools and guidelines are described for constructing a FEM for the space station under consideration. The methods used to analyze the sensitivity of PNP to variations in design, are described. Ways are suggested for developing contour plots of the sensitivity study data. Additional BUMPER analysis examples are provided, including FEMs, command inputs, and data outputs. The mathematical theory used as the basis for the code is described, and illustrates the data flow within the analysis.

Designing divertor targets for uniform power load

NASA Astrophysics Data System (ADS)

Dekeyser, W.; Reiter, D.; Baelmans, M.

2015-08-01

Divertor design for next step fusion reactors heavily relies on 2D edge plasma modeling with codes as e.g. B2-EIRENE. While these codes are typically used in a design-by-analysis approach, in previous work we have shown that divertor design can alternatively be posed as a mathematical optimization problem, and solved very efficiently using adjoint methods adapted from computational aerodynamics. This approach has been applied successfully to divertor target shape design for more uniform power load. In this paper, the concept is further extended to include all contributions to the target power load, with particular focus on radiation. In a simplified test problem, we show the potential benefits of fully including the radiation load in the design cycle as compared to only assessing this load in a post-processing step.

An Efficient Estimator for Moving Target Localization Using Multi-Station Dual-Frequency Radars.

PubMed

Huang, Jiyan; Zhang, Ying; Luo, Shan

2017-12-15

Localization of a moving target in a dual-frequency radars system has now gained considerable attention. The noncoherent localization approach based on a least squares (LS) estimator has been addressed in the literature. Compared with the LS method, a novel localization method based on a two-step weighted least squares estimator is proposed to increase positioning accuracy for a multi-station dual-frequency radars system in this paper. The effects of signal noise ratio and the number of samples on the performance of range estimation are also analyzed in the paper. Furthermore, both the theoretical variance and Cramer-Rao lower bound (CRLB) are derived. The simulation results verified the proposed method.

78 FR 22529 - Information on Surplus Land at a Military Installation Designated for Disposal: Naval Air Station...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-16

... Installation Designated for Disposal: Naval Air Station Alameda, Alameda, California AGENCY: Department of the... at Naval Air Station Alameda, Alameda, California. FOR FURTHER INFORMATION CONTACT: Ms. Laura Duchnak, Director, Naval Facilities Engineering Command, Base Realignment and Closure Program Management Office...

Central station applications planning activities and supporting studies. [application of photovoltaic technology to power generation plants

NASA Technical Reports Server (NTRS)

Leonard, S. L.; Siegel, B.

1980-01-01

The application of photovoltaic technology in central station (utility) power generation plants is considered. A program of data collection and analysis designed to provide additional information about the subset of the utility market that was identified as the initial target for photovoltaic penetration, the oil-dependent utilities (especially muncipals) of the U.S. Sunbelt, is described along with a series of interviews designed to ascertain utility industry opinions about the National Photovoltaic Program as it relates to central station applications.

Shock Ignition Target Design for Inertial Fusion Energy

DTIC Science & Technology

2010-01-01

Shock ignition target design for inertial fusion energy Andrew J. Schmitt,1, a) Jason W. Bates,1 Steven P. Obenschain,1 Steven T. Zalesak,2 and David...2010 to 00-00-2010 4. TITLE AND SUBTITLE Shock ignition target design for inertial fusion energy 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM

Nanogel Carrier Design for Targeted Drug Delivery

PubMed Central

Eckmann, D. M.; Composto, R. J.; Tsourkas, A.; Muzykantov, V. R.

2014-01-01

Polymer-based nanogel formulations offer features attractive for drug delivery, including ease of synthesis, controllable swelling and viscoelasticity as well as drug loading and release characteristics, passive and active targeting, and the ability to formulate nanogel carriers that can respond to biological stimuli. These unique features and low toxicity make the nanogels a favorable option for vascular drug targeting. In this review, we address key chemical and biological aspects of nanogel drug carrier design. In particular, we highlight published studies of nanogel design, descriptions of nanogel functional characteristics and their behavior in biological models. These studies form a compendium of information that supports the scientific and clinical rationale for development of this carrier for targeted therapeutic interventions. PMID:25485112

Space station, 1959 to . .

NASA Astrophysics Data System (ADS)

Butler, G. V.

1981-04-01

Early space station designs are considered, taking into account Herman Oberth's first space station, the London Daily Mail Study, the first major space station design developed during the moon mission, and the Manned Orbiting Laboratory Program of DOD. Attention is given to Skylab, new space station studies, the Shuttle and Spacelab, communication satellites, solar power satellites, a 30 meter diameter radiometer for geological measurements and agricultural assessments, the mining of the moons, and questions of international cooperation. It is thought to be very probable that there will be very large space stations at some time in the future. However, for the more immediate future a step-by-step development that will start with Spacelab stations of 3-4 men is envisaged.

Conceptual design for the Space Station Freedom fluid physics/dynamics facility

NASA Technical Reports Server (NTRS)

Thompson, Robert L.; Chucksa, Ronald J.; Omalley, Terence F.; Oeftering, Richard C.

1993-01-01

A study team at NASA's Lewis Research Center has been working on a definition study and conceptual design for a fluid physics and dynamics science facility that will be located in the Space Station Freedom's baseline U.S. Laboratory module. This modular, user-friendly facility, called the Fluid Physics/Dynamics Facility, will be available for use by industry, academic, and government research communities in the late 1990's. The Facility will support research experiments dealing with the study of fluid physics and dynamics phenomena. Because of the lack of gravity-induced convection, research into the mechanisms of fluids in the absence of gravity will help to provide a better understanding of the fundamentals of fluid processes. This document has been prepared as a final version of the handout for reviewers at the Fluid Physics/Dynamics Facility Assessment Workshop held at Lewis on January 24 and 25, 1990. It covers the background, current status, and future activities of the Lewis Project Study Team effort. It is a revised and updated version of a document entitled 'Status Report on the Conceptual Design for the Space Station Fluid Physics/Dynamics Facility', dated January 1990.

Design and realization of an automatic weather station at island

NASA Astrophysics Data System (ADS)

Chen, Yong-hua; Li, Si-ren

2011-10-01

In this paper, the design and development of an automatic weather station monitoring is described. The proposed system consists of a set of sensors for measuring meteorological parameters (temperature, wind speed & direction, rain fall, visibility, etc.). To increase the reliability of the system, wind speed & direction are measured redundantly with duplicate sensors. The sensor signals are collected by the data logger CR1000 at several analog and digital inputs. The CR1000 and the sensors form a completely autonomous system which works with the other systems installed in the container. Communication with the master PC is accomplished over the method of Code Division Multiple Access (CDMA) with the Compact Caimore6550P CDMA DTU. The data are finally stored in tables on the CPU as well as on the CF-Card. The weather station was built as an efficient autonomous system which operates with the other systems to provide the required data for a fully automatic measurement system.

The Space Station Freedom Flight Telerobotic Servicer - The design and evolution of a dexterous space robot

NASA Technical Reports Server (NTRS)

Mccain, Harry G.; Andary, James F.; Hewitt, Dennis R.; Haley, Dennis C.

1990-01-01

The Flight Telerobotic Servicer (FTS) will provide a telerobotic capability to the Space Station in the early assembly phases of the program and will be used for assembly, maintenance, and inspection throughout the lifetime of the Station. Here, the FTS design approach to the development of autonomous capabilities is discussed. The FTS telerobotic workstations for the Shuttle and Space Station, and facility for on-orbit storage are examined. The rationale of the FTS with regard to ease of operation, operational versatility, maintainability, safety, and control is discussed.

The environment workbench: A design tool for Space Station Freedom

NASA Technical Reports Server (NTRS)

Jongeward, Gary A.; Kuharski, Robert A.; Rankin, Thomas V.; Wilcox, Katherine G.; Roche, James C.

1991-01-01

The environment workbench (EWB) is being developed for NASA by S-CUBED to provide a standard tool that can be used by the Space Station Freedom (SSF) design and user community for requirements verification. The desktop tool will predict and analyze the interactions of SSF with its natural and self-generated environments. A brief review of the EWB design and capabilities is presented. Calculations using a prototype EWB of the on-orbit floating potentials and contaminant environment of SSF are also presented. Both the positive and negative grounding configurations for the solar arrays are examined to demonstrate the capability of the EWB to provide quick estimates of environments, interactions, and system effects.

Challenges of Sustaining the International Space Station Through 2020 and Beyond: Reassessing Confidence Targets for System Availability

NASA Technical Reports Server (NTRS)

Lutomski, Michael G.; Carter-Journet, Katrina; Anderson, Leif; Box, Neil; Harrington, Sean; Jackson, David; DiFilippo, Denise

2012-01-01

The International Space Station (ISS) was originally designed to operate until 2015 with a plan for deorbiting the ISS in 2016. Currently, the international partnership has agreed to extend the operations until 2020 and discussions are underway to extend the life even further to 2028. Each partner is responsible for the sustaining engineering, sparing, and maintenance of their own segments. National Aeronautics and Space Administration's (NASA's) challenge is to purchase the needed number of spares to maintain the functional availability of the ISS systems necessary for the United States On-Orbit Segment s contribution. This presentation introduces an analytical approach to assessing uncertainty in ISS hardware necessary to extend the life of the vehicle. Some key areas for consideration are: establishing what confidence targets are required to ensure science can be continuously carried out on the ISS, defining what confidence targets are reasonable to ensure vehicle survivability, considering what is required to determine if the confidence targets are too high, and whether sufficient number of spares are purchased. The results of the analysis will provide a methodological basis for reassessing vehicle subsystem confidence targets. This analysis compares the probability of existing spares exceeding the total expected unit demand of the Orbital Replacement Unit (ORU) in functional hierarchies approximating the vehicle subsystems. In cases where the functional hierarchies' availability does not meet subsystem confidence targets, the analysis will further identify which ORUs may require additional spares to extend the life of the ISS. The resulting probability is dependent upon hardware reliability estimates. However, the ISS hardware fleet carries considerable epistemic uncertainty which must be factored into the development and execution of sparing risk postures. In addition, it is also recognized that uncertainty in the assessment is due to disconnects between

Pilot's Desk Flight Station

NASA Technical Reports Server (NTRS)

Sexton, G. A.

1984-01-01

Aircraft flight station designs have generally evolved through the incorporation of improved or modernized controls and displays. In connection with a continuing increase in the amount of information displayed, this process has produced a complex and cluttered conglomeration of knobs, switches, and electromechanical displays. The result was often high crew workload, missed signals, and misinterpreted information. Advances in electronic technology have now, however, led to new concepts in flight station design. An American aerospace company in cooperation with NASA has utilized these concepts to develop a candidate conceptual design for a 1995 flight station. The obtained Pilot's Desk Flight Station is a unique design which resembles more an operator's console than today's cockpit. Attention is given to configuration, primary flight controllers, front panel displays, flight/navigation display, approach charts and weather display, head-up display, and voice command and response systems.

A Ten-Meter Ground-Station Telescope for Deep-Space Optical Communications: A Preliminary Design

NASA Technical Reports Server (NTRS)

Britcliffe, M.; Hoppe, D.; Roberts, W.; Page, N.

2001-01-01

This article describes a telescope design for a 10-m optical ground station for deep-space communications. The design for a direct-detection optical communications telescope differs dramatically from a telescope for imaging applications. In general, the requirements for optical manufacturing and tracking performance are much less stringent for direct detection of optical signals. The technical challenge is providing a design that will operate in the daytime/nighttime conditions required for a Deep Space Network tracking application. The design presented addresses these requirements. The design will provide higher performance at lower cost than existing designs.

Transportation node space station conceptual design

NASA Technical Reports Server (NTRS)

1988-01-01

A number of recent studies have addressed the problem of a transportation node space station. How things would change or what addition facilities would be needed to support a major lunar or Mars initiative is a much often asked question. The support of a lunar base, requiring stacks on the order of 200 metric tons each to land 25 m tons on the lunar surface with reusable vehicles is addressed. The problem of maintaining and reusing large single stage Orbit Transfer Vehicles (OTVs) and single stage lander/launchers in space are examined. The required people and equipment needed, to maintain these vehicles are only vaguely known at present. The people and equipment needed depend on how well the OTV and lander/launcher can be designed for easy reuse. Since the OTV and lander/launcher are only conceptually defined at present, the real maintenance and refurbishment requirements are unobtainable. An estimate of what is needed, based on previous studies and obvious requirements was therefore made. An attempt was made to err on the conservative side.

An Efficient Estimator for Moving Target Localization Using Multi-Station Dual-Frequency Radars

PubMed Central

Zhang, Ying; Luo, Shan

2017-01-01

Localization of a moving target in a dual-frequency radars system has now gained considerable attention. The noncoherent localization approach based on a least squares (LS) estimator has been addressed in the literature. Compared with the LS method, a novel localization method based on a two-step weighted least squares estimator is proposed to increase positioning accuracy for a multi-station dual-frequency radars system in this paper. The effects of signal noise ratio and the number of samples on the performance of range estimation are also analyzed in the paper. Furthermore, both the theoretical variance and Cramer–Rao lower bound (CRLB) are derived. The simulation results verified the proposed method. PMID:29244727

Proceedings of the Flat-Plate Solar Array Project Research Forum on the Design of Flat-Plate Photovoltaic Arrays for Central Stations

NASA Technical Reports Server (NTRS)

1983-01-01

The Flat Plate Solar Array Project, focuses on advancing technologies relevant to the design and construction of megawatt level central station systems. Photovoltaic modules and arrays for flat plate central station or other large scale electric power production facilities require the establishment of a technical base that resolves design issues and results in practical and cost effective configurations. Design, qualification and maintenance issues related to central station arrays derived from the engineering and operating experiences of early applications and parallel laboratory reserch activities are investigated. Technical issues are examined from the viewpoint of the utility engineer, architect/engineer and laboratory researcher. Topics on optimum source circuit designs, module insulation design for high system voltages, array safety, structural interface design, measurements, and array operation and maintenance are discussed.

An inexpensive and reliable monitoring station design for use with lightweight, compact data loggers

Treesearch

Ronald S., Jr. Zalesny; Adam H. Wiese; Edmund O. Bauer; William L., Jr. Headlee; Richard B. Hall; A. Assibi Mahama; Jill A. Zalesny

2007-01-01

We designed, constructed, and field-tested an inexpensive and reliable monitoring station that can be used with lightweight, compact data loggers. We feel this design, improved three times over 6 yr, could benefit anyone in nursery or field settings interested in acquiring environmental data. We provide step-by-step instructions on the construction of the monitoring...

Targeting targeted agents: open issues for clinical trial design.

PubMed

Bria, Emilio; Di Maio, Massimo; Carlini, Paolo; Cuppone, Federica; Giannarelli, Diana; Cognetti, Francesco; Milella, Michele

2009-05-22

Molecularly targeted agents for the treatment of solid tumors had entered the market in the last 5 years, with a great impact upon both the scientific community and the society. Many randomized phase III trials conducted in recent years with new targeted agents, despite previous data coming from preclinical research and from phase II trials were often promising, have produced disappointingly negative results. Some other trials have actually met their primary endpoint, demonstrating a statistically significant result favouring the experimental treatment. Unfortunately, with a few relevant exceptions, this advantage is often small, if not negligible, in absolute terms. The difference between statistical significance and clinical relevance should always be considered when translating clinical trials' results in the practice. The reason why this 'revolution' did not significantly impact on cancer treatment to displace chemotherapy from the patient' bedside is in part due to complicated, and in many cases, unknown, mechanisms of action of such drugs; indeed, the traditional way the clinical investigators were used to test the efficacy of 'older' chemotherapeutics, has become 'out of date' from the methodological perspective. As these drugs should be theoretically tailored upon featured bio-markers expressed by the patients, the clinical trial design should follow new rules based upon stronger hypotheses than those developed so far. Indeed, the early phases of basic and clinical drug development are crucial in the correct process which is able to correctly identify the target (when present). Targeted trial designs can result in easier studies, with less, better selected, and supported by stronger proofs of response evidences, patients, in order to not waste time and resources.

Intelligent Virtual Station (IVS)

NASA Technical Reports Server (NTRS)

2002-01-01

The Intelligent Virtual Station (IVS) is enabling the integration of design, training, and operations capabilities into an intelligent virtual station for the International Space Station (ISS). A viewgraph of the IVS Remote Server is presented.

Space Station Human Factors: Designing a Human-Robot Interface

NASA Technical Reports Server (NTRS)

Rochlis, Jennifer L.; Clarke, John Paul; Goza, S. Michael

2001-01-01

The experiments described in this paper are part of a larger joint MIT/NASA research effort and focus on the development of a methodology for designing and evaluating integrated interfaces for highly dexterous and multifunctional telerobot. Specifically, a telerobotic workstation is being designed for an Extravehicular Activity (EVA) anthropomorphic space station telerobot called Robonaut. Previous researchers have designed telerobotic workstations based upon performance of discrete subsets of tasks (for example, peg-in-hole, tracking, etc.) without regard for transitions that operators go through between tasks performed sequentially in the context of larger integrated tasks. The experiments presented here took an integrated approach to describing teleoperator performance and assessed how subjects operating a full-immersion telerobot perform during fine position and gross position tasks. In addition, a Robonaut simulation was also developed as part of this research effort, and experimentally tested against Robonaut itself to determine its utility. Results show that subject performance of teleoperated tasks using both Robonaut and the simulation are virtually identical, with no significant difference between the two. These results indicate that the simulation can be utilized as both a Robonaut training tool, and as a powerful design platform for telepresence displays and aids.

Changing paradigm from one target one ligand towards multi target directed ligand design for key drug targets of Alzheimer disease: An important role of Insilco methods in multi target directed ligands design.

PubMed

Kumar, Akhil; Tiwari, Ashish; Sharma, Ashok

2018-03-15

Alzheimer disease (AD) is now considered as a multifactorial neurodegenerative disorder and rapidly increasing to an alarming situation and causing higher death rate. One target one ligand hypothesis is not able to provide complete solution of AD due to multifactorial nature of disease and one target one drug seems to fail to provide better treatment against AD. Moreover, current available treatments are limited and most of the upcoming treatments under clinical trials are based on modulating single target. So the current AD drug discovery research shifting towards new approach for better solution that simultaneously modulate more than one targets in the neurodegenerative cascade. This can be achieved by network pharmacology, multi-modal therapies, multifaceted, and/or the more recently proposed term "multi-targeted designed drugs. Drug discovery project is tedious, costly and long term project. Moreover, multi target AD drug discovery added extra challenges such as good binding affinity of ligands for multiple targets, optimal ADME/T properties, no/less off target side effect and crossing of the blood brain barrier. These hurdles may be addressed by insilico methods for efficient solution in less time and cost as computational methods successfully applied to single target drug discovery project. Here we are summarizing some of the most prominent and computationally explored single target against AD and further we discussed successful example of dual or multiple inhibitors for same targets. Moreover we focused on ligand and structure based computational approach to design MTDL against AD. However is not an easy task to balance dual activity in a single molecule but computational approach such as virtual screening docking, QSAR, simulation and free energy are useful in future MTDLs drug discovery alone or in combination with fragment based method. However, rational and logical implementations of computational drug designing methods are capable of assisting AD drug

An intelligent control and virtual display system for evolutionary space station workstation design

NASA Technical Reports Server (NTRS)

Feng, Xin; Niederjohn, Russell J.; Mcgreevy, Michael W.

1992-01-01

Research and development of the Advanced Display and Computer Augmented Control System (ADCACS) for the space station Body-Ported Cupola Virtual Workstation (BP/VCWS) were pursued. The potential applications were explored of body ported virtual display and intelligent control technology for the human-system interfacing applications is space station environment. The new system is designed to enable crew members to control and monitor a variety of space operations with greater flexibility and efficiency than existing fixed consoles. The technologies being studied include helmet mounted virtual displays, voice and special command input devices, and microprocessor based intelligent controllers. Several research topics, such as human factors, decision support expert systems, and wide field of view, color displays are being addressed. The study showed the significant advantages of this uniquely integrated display and control system, and its feasibility for human-system interfacing applications in the space station command and control environment.

Space station group activities habitability module study

NASA Technical Reports Server (NTRS)

Nixon, David

1986-01-01

This study explores and analyzes architectural design approaches for the interior of the Space Station Habitability Module (originally defined as Habitability Module 1 in Space Station Reference Configuration Decription, JSC-19989, August 1984). In the Research Phase, architectural program and habitability design guidelines are specified. In the Schematic Design Phase, a range of alternative concepts is described and illustrated with drawings, scale-model photographs and design analysis evaluations. Recommendations are presented on the internal architectural, configuration of the Space Station Habitability Module for such functions as the wardroom, galley, exercise facility, library and station control work station. The models show full design configurations for on-orbit performance.

Space Station

NASA Image and Video Library

1969-01-01

This picture illustrates a concept of a 33-Foot-Diameter Space Station Leading to a Space Base. In-house work of the Marshall Space Flight Center, as well as a Phase B contract with the McDornel Douglas Astronautics Company, resulted in a preliminary design for a space station in 1969 and l970. The Marshall-McDonnel Douglas approach envisioned the use of two common modules as the core configuration of a 12-man space station. Each common module was 33 feet in diameter and 40 feet in length and provided the building blocks, not only for the space station, but also for a 50-man space base. Coupled together, the two modules would form a four-deck facility: two decks for laboratories and two decks for operations and living quarters. Zero-gravity would be the normal mode of operation, although the station would have an artificial gravity capability. This general-purpose orbital facility was to provide wide-ranging research capabilities. The design of the facility was driven by the need to accommodate a broad spectrum of activities in support of astronomy, astrophysics, aerospace medicine, biology, materials processing, space physics, and space manufacturing. To serve the needs of Earth observations, the station was to be placed in a 242-nautical-mile orbit at a 55-degree inclination. An Intermediate-21 vehicle (comprised of Saturn S-IC and S-II stages) would have launched the station in 1977.

International Space Station Crew Restraint Design

NASA Technical Reports Server (NTRS)

Whitmore, M.; Norris, L.; Holden, K.

2005-01-01

With permanent human presence onboard the International Space Station (ISS), crews will be living and working in microgravity, dealing with the challenges of a weightless environment. In addition, the confined nature of the spacecraft environment results in ergonomic challenges such as limited visibility and access to the activity areas, as well as prolonged periods of unnatural postures. Without optimum restraints, crewmembers may be handicapped for performing some of the on-orbit tasks. Currently, many of the tasks on ISS are performed with the crew restrained merely by hooking their arms or toes around handrails to steady themselves. This is adequate for some tasks, but not all. There have been some reports of discomfort/calluses on the top of the toes. In addition, this type of restraint is simply insufficient for tasks that require a large degree of stability. Glovebox design is a good example of a confined workstation concept requiring stability for successful use. They are widely used in industry, university, and government laboratories, as well as in the space environment, and are known to cause postural limitations and visual restrictions. Although there are numerous guidelines pertaining to ventilation, seals, and glove attachment, most of the data have been gathered in a 1-g environment, or are from studies that were conducted prior to the early 1980 s. Little is known about how best to restrain a crewmember using a glovebox in microgravity. In 2004, The Usability Testing and Analysis Facility (UTAF) at the NASA Johnson Space Center completed development/evaluation of several design concepts for crew restraints to meet the various needs outlined above. Restraints were designed for general purpose use, for teleoperation (Robonaut) and for use with the Life Sciences Glovebox. All design efforts followed a human factors engineering design lifecycle, beginning with identification of requirements followed by an iterative prototype/test cycle. Anthropometric

Modular space station phase B extension preliminary performance specification. Volume 1: Initial station systems

NASA Technical Reports Server (NTRS)

1971-01-01

The general, operational, design/construction, and subsystem design requirements are presented for a solar powered modular space station system. While these requirements apply only to the initial station system, the system is readily adaptable to a growth configuration.

Space Station

NASA Image and Video Library

1970-01-01

This is an illustration of the Space Base concept. In-house work of the Marshall Space Flight Center, as well as a Phase B contract with the McDornel Douglas Astronautics Company, resulted in a preliminary design for a space station in 1969 and l970. The Marshall-McDonnel Douglas approach envisioned the use of two common modules as the core configuration of a 12-man space station. Each common module was 33 feet in diameter and 40 feet in length and provided the building blocks, not only for the space station, but also for a 50-man space base. Coupled together, the two modules would form a four-deck facility: two decks for laboratories and two decks for operations and living quarters. Zero-gravity would be the normal mode of operation, although the station would have an artificial-gravity capability. This general-purpose orbital facility was to provide wide-ranging research capabilities. The design of the facility was driven by the need to accommodate a broad spectrum of activities in support of astronomy, astrophysics, aerospace medicine, biology, materials processing, space physics, and space manufacturing. To serve the needs of Earth observations, the station was to be placed in a 242-nautical-mile orbit at a 55-degree inclination. An Intermediate-21 vehicle (comprised of Saturn S-IC and S-II stages) would have launched the station in 1977.

Design and simulation of a fast-charging station for plug-in hybrid electric vehicle (PHEV) batteries

NASA Astrophysics Data System (ADS)

de Leon, Nathalie Pulmones

2011-12-01

With the increasing interest in green technologies in transportation, plug-in hybrid electric vehicles (PHEV) have proven to be the best short-term solution to minimize greenhouse gas emissions. Despite such interest, conventional vehicle drivers are still reluctant in using such a new technology, mainly because of the long duration (4-8 hours) required to charge PHEV batteries with the currently existing Level I and II chargers. For this reason, Level III fast-charging stations capable of reducing the charging duration to 10-15 minutes are being considered. The present thesis focuses on the design of a fast-charging station that uses, in addition to the electrical grid, two stationary energy storage devices: a flywheel energy storage and a supercapacitor. The power electronic converters used for the interface of the energy sources with the charging station are designed. The design also focuses on the energy management that will minimize the PHEV battery charging duration as well as the duration required to recharge the energy storage devices. For this reason, an algorithm that minimizes durations along with its mathematical formulation is proposed, and its application in fast charging environment will be illustrated by means of two scenarios.

Using computer graphics to design Space Station Freedom viewing

NASA Technical Reports Server (NTRS)

Goldsberry, Betty S.; Lippert, Buddy O.; Mckee, Sandra D.; Lewis, James L., Jr.; Mount, Francis E.

1993-01-01

Viewing requirements were identified early in the Space Station Freedom program for both direct viewing via windows and indirect viewing via cameras and closed-circuit television (CCTV). These requirements reside in NASA Program Definition and Requirements Document (PDRD), Section 3: Space Station Systems Requirements. Currently, analyses are addressing the feasibility of direct and indirect viewing. The goal of these analyses is to determine the optimum locations for the windows, cameras, and CCTV's in order to meet established requirements, to adequately support space station assembly, and to operate on-board equipment. PLAID, a three-dimensional computer graphics program developed at NASA JSC, was selected for use as the major tool in these analyses. PLAID provides the capability to simulate the assembly of the station as well as to examine operations as the station evolves. This program has been used successfully as a tool to analyze general viewing conditions for many Space Shuttle elements and can be used for virtually all Space Station components. Additionally, PLAID provides the ability to integrate an anthropometric scale-modeled human (representing a crew member) with interior and exterior architecture.

Design of a Base Station for MEMS CCR Localization in an Optical Sensor Network

PubMed Central

Park, Chan Gook; Jeon, Hyun Cheol; Kim, Hyoun Jin; Kim, Jae Yoon

2014-01-01

This paper introduces a design and implementation of a base station, capable of positioning sensor nodes using an optical scheme. The base station consists of a pulse laser module, optical detectors and beam splitter, which are mounted on a rotation-stage, and a Time to Digital Converter (TDC). The optical pulse signal transmitted to the sensor node with a Corner Cube Retro-reflector (CCR) is reflected to the base station, and the Time of Flight (ToF) data can be obtained from the two detectors. With the angle and flight time data, the position of the sensor node can be calculated. The performance of the system is evaluated by using a commercial CCR. The sensor nodes are placed at different angles from the base station and scanned using the laser. We analyze the node position error caused by the rotation and propose error compensation methods, namely the outlier sample exception and decreasing the confidence factor steadily using the recursive least square (RLS) methods. Based on the commercial CCR results, the MEMS CCR is also tested to demonstrate the compatibility between the base station and the proposed methods. The result shows that the localization performance of the system can be enhanced with the proposed compensation method using the MEMS CCR. PMID:24815681

Design of a base station for MEMS CCR localization in an optical sensor network.

PubMed

Park, Chan Gook; Jeon, Hyun Cheol; Kim, Hyoun Jin; Kim, Jae Yoon

2014-05-08

This paper introduces a design and implementation of a base station, capable of positioning sensor nodes using an optical scheme. The base station consists of a pulse laser module, optical detectors and beam splitter, which are mounted on a rotation-stage, and a Time to Digital Converter (TDC). The optical pulse signal transmitted to the sensor node with a Corner Cube Retro-reflector (CCR) is reflected to the base station, and the Time of Flight (ToF) data can be obtained from the two detectors. With the angle and flight time data, the position of the sensor node can be calculated. The performance of the system is evaluated by using a commercial CCR. The sensor nodes are placed at different angles from the base station and scanned using the laser. We analyze the node position error caused by the rotation and propose error compensation methods, namely the outlier sample exception and decreasing the confidence factor steadily using the recursive least square (RLS) methods. Based on the commercial CCR results, the MEMS CCR is also tested to demonstrate the compatibility between the base station and the proposed methods. The result shows that the localization performance of the system can be enhanced with the proposed compensation method using the MEMS CCR.

Dual Target Design for CLAS12

NASA Astrophysics Data System (ADS)

Alam, Omair; Gilfoyle, Gerard; Christo, Steve

2015-10-01

An experiment to measure the neutron magnetic form factor (GnM) is planned for the new CLAS12 detector in Hall B at Jefferson Lab. This form factor will be extracted from the ratio of the quasielastic electron-neutron to electron-proton scattering off a liquid deuterium (LD2) target. A collinear liquid hydrogen (LH2) target will be used to measure efficiencies at the same time as production data is collected from the LD2 target. To test target designs we have simulated CLAS12 and the target geometry. Electron-nucleon events are produced first with the QUasiElastic Event Generator (QUEEG) which models the internal motion of the nucleons in deuterium.1 The results are used as input to the CLAS12 Monte Caro code gemc; a Geant4-based program that simulates the particle's interactions with each component of CLAS12 including the target material. The dual target geometry has been added to gemc including support structures and cryogenic transport systems. A Perl script was written to define the target materials and geometries. The output of the script is a set of database entries read by gemc at runtime. An initial study of the impact of this dual-target structure revealed limited effects on the electron momentum and angular resolutions. Work supported by the University of Richmond and the US Department of Energy.

Space station user's handbook

NASA Technical Reports Server (NTRS)

1972-01-01

A user's handbook for the modular space station concept is presented. The document is designed to acquaint science personnel with the overall modular space station program, the general nature and capabilities of the station itself, some of the scientific opportunities presented by the station, the general policy governing its operation, and the relationship between the program and participants from the scientific community.

A Camera and Multi-Sensor Automated Station Design for Polar Physical and Biological Systems Monitoring: AMIGOS

NASA Astrophysics Data System (ADS)

Bohlander, J. A.; Ross, R.; Scambos, T.; Haran, T. M.; Bauer, R. J.

2012-12-01

The Automated Meteorology - Ice/Indigenous species - Geophysics Observation System (AMIGOS) consists of a set of measurement instruments and camera(s) controlled by a single-board computer with a simplified Linux operating system and an Iridium satellite modem supporting two-way communication. Primary features of the system relevant to polar operations are low power requirements, daily data uploading, reprogramming, tolerance for low temperatures, and various approaches for automatic resets and recovery from low power or cold shut-down. Instruments include a compact weather station, C/A or dual-frequency GPS, solar flux and reflectivity sensors, sonic snow gages, simplified radio-echo-sounder, and resistance thermometer string in the firn column. In the current state of development, there are two basic designs. One is intended for in situ observations of glacier conditions. The other design supports a high-resolution camera for monitoring biological or geophysical systems from short distances (100 m to 20 km). The stations have been successfully used in several locations for operational support, monitoring rapid ice changes in response to climate change or iceberg drift, and monitoring penguin colony activity. As of June, 2012, there are 9 AMIGOS systems installed, all on the Antarctic continent. The stations are a working prototype for a planned series of upgraded stations, currently termed 'Sentinels'. These stations would carry further instrumentation, communications, and processing capability to investigate ice - ocean interaction from ice tongue, ice shelf, or fjord coastline areas.

Enabler operator station

NASA Technical Reports Server (NTRS)

Bailey, Andrea; Kietzman, John; King, Shirlyn; Stover, Rae; Wegner, Torsten

1992-01-01

The objective of this project was to design an onboard operator station for the conceptual Lunar Work Vehicle (LWV). The LWV would be used in the colonization of a lunar outpost. The details that follow, however, are for an Earth-bound model. The operator station is designed to be dimensionally correct for an astronaut wearing the current space shuttle EVA suit (which include life support). The proposed operator station will support and restrain an astronaut as well as to provide protection from the hazards of vehicle rollover. The threat of suit puncture is eliminated by rounding all corners and edges. A step-plate, located at the front of the vehicle, provides excellent ease of entry and exit. The operator station weight requirements are met by making efficient use of rigid members, semi-rigid members, and woven fabrics.

Quantifying design trade-offs of beryllium targets on NIF

NASA Astrophysics Data System (ADS)

Yi, S. A.; Zylstra, A. B.; Kline, J. L.; Loomis, E. N.; Kyrala, G. A.; Shah, R. C.; Perry, T. S.; Kanzleiter, R. J.; Batha, S. H.; MacLaren, S. A.; Ralph, J. E.; Masse, L. P.; Salmonson, J. D.; Tipton, R. E.; Callahan, D. A.; Hurricane, O. A.

2017-10-01

An important determinant of target performance is implosion kinetic energy, which scales with the capsule size. The maximum achievable performance for a given laser is thus related to the largest capsule that can be imploded symmetrically, constrained by drive uniformity. A limiting factor for symmetric radiation drive is the ratio of hohlraum to capsule radii, or case-to-capsule ratio (CCR). For a fixed laser energy, a larger hohlraum allows for driving bigger capsules symmetrically at the cost of reduced peak radiation temperature (Tr). Beryllium ablators may thus allow for unique target design trade-offs due to their higher ablation efficiency at lower Tr. By utilizing larger hohlraum sizes than most modern NIF designs, beryllium capsules thus have the potential to operate in unique regions of the target design parameter space. We present design simulations of beryllium targets with a large CCR = 4.3 3.7 . These are scaled surrogates of large hohlraum low Tr beryllium targets, with the goal of quantifying symmetry tunability as a function of CCR. This work performed under the auspices of the U.S. DOE by LANL under contract DE-AC52- 06NA25396, and by LLNL under Contract DE-AC52-07NA27344.

Evolutionary Multiobjective Design Targeting a Field Programmable Transistor Array

NASA Technical Reports Server (NTRS)

Aguirre, Arturo Hernandez; Zebulum, Ricardo S.; Coello, Carlos Coello

2004-01-01

This paper introduces the ISPAES algorithm for circuit design targeting a Field Programmable Transistor Array (FPTA). The use of evolutionary algorithms is common in circuit design problems, where a single fitness function drives the evolution process. Frequently, the design problem is subject to several goals or operating constraints, thus, designing a suitable fitness function catching all requirements becomes an issue. Such a problem is amenable for multi-objective optimization, however, evolutionary algorithms lack an inherent mechanism for constraint handling. This paper introduces ISPAES, an evolutionary optimization algorithm enhanced with a constraint handling technique. Several design problems targeting a FPTA show the potential of our approach.

Space station ventilation study

NASA Technical Reports Server (NTRS)

Colombo, G. V.; Allen, G. E.

1972-01-01

A ventilation system design and selection method which is applicable to any manned vehicle were developed. The method was used to generate design options for the NASA 33-foot diameter space station, all of which meet the ventilation system design requirements. System characteristics such as weight, volume, and power were normalized to dollar costs for each option. Total system costs for the various options ranged from a worst case $8 million to a group of four which were all approximately $2 million. A system design was then chosen from the $2 million group and is presented in detail. A ventilation system layout was designed for the MSFC space station mockup which provided comfortable, efficient ventilation of the mockup. A conditioned air distribution system design for the 14-foot diameter modular space station, using the same techniques, is also presented. The tradeoff study resulted in the selection of a system which costs $1.9 million, as compared to the alternate configuration which would have cost $2.6 million.

Preliminary design of a satellite observation system for Space Station Freedom

NASA Technical Reports Server (NTRS)

Cabe, Greg (Editor); Gallagher, Chris; Wilson, Brian; Rehfeld, James; Maurer, Alexa; Stern, Dan; Nualart, Jaime; Le, Xuan-Trang

1992-01-01

Degobah Satellite Systems (DSS), in cooperation with the University Space Research Association (USRA), NASA - Johnson Space Center (JSC), and the University of Texas, has completed the preliminary design of a satellite system to provide inexpensive on-demand video images of all or any portion of Space Station Freedom (SSF). DSS has narrowed the scope of the project to complement the work done by Mr. Dennis Wells at Johnson Space Center. This three month project has resulted in completion of the preliminary design of AERCAM, the Autonomous Extravehicular Robotic Camera, detailed in this design report. This report begins by providing information on the project background, describing the mission objectives, constraints, and assumptions. Preliminary designs for the primary concept and satellite subsystems are then discussed in detail. Included in the technical portion of the report are detailed descriptions of an advanced imaging system and docking and safing systems that ensure compatibility with the SSF. The report concludes by describing management procedures and project costs.

International Space Station Evolution Data Book. Volume 1; Baseline Design; Revised

NASA Technical Reports Server (NTRS)

Jorgensen, Catherine A. (Editor); Antol, Jeffrey (Technical Monitor)

2000-01-01

The International Space Station (ISS) will provide an Earth-orbiting facility that will accommodate engineering experiments as well as research in a microgravity environment for life and natural sciences. The ISS will distribute resource utilities and support permanent human habitation for conducting this research and experimentation in a safe and habitable environment. The objectives of the ISS program are to develop a world-class, international orbiting laboratory for conducting high-value scientific research for the benefit of humans on Earth; to provide access to the microgravity environment; to develop the ability to live and work in space for extended periods; and to provide a research test bed for developing advanced technology for human and robotic exploration of space. The current design and development of the ISS has been achieved through the outstanding efforts of many talented engineers, designers, technicians, and support personnel who have dedicated their time and hard work to producing a state-of-the-art Space Station. Despite these efforts, the current design of the ISS has limitations that have resulted from cost and technology issues. Regardless, the ISS must evolve during its operational lifetime to respond to changing user needs and long-term national and international goals. As technologies develop and user needs change, the ISS will be modified to meet these demands. The design and development of these modifications should begin now to prevent a significant lapse in time between the baseline design and the realization of future opportunities. For this effort to begin, an understanding of the baseline systems and current available opportunities for utilization needs to be achieved. Volume I of this document provides the consolidated overview of the ISS baseline systems. It also provides information on the current facilities available for pressurized and unpressurized payloads. Information on current plans for crew availability and utilization

The space station freedom flight telerobotic servicer. The design and evolution of a dexterous space robot

NASA Astrophysics Data System (ADS)

McCain, Harry G.; Andary, James F.; Hewitt, Dennis R.; Haley, Dennis C.

The Flight Telerobotic Servicer (FTS) Project at the Goddard Space Flight Center is developing an advanced telerobotic system to assist in and reduce crew extravehicular activity (EVA) for Space Station Freedom (SSF). The FTS will provide a telerobotic capability to the Freedom Station in the early assembly phases of the program and will be employed for assembly, maintenance, and inspection applications throughout the lifetime of the space station. Appropriately configured elements of the FTS will also be employed for robotic manipulation in remote satellite servicing applications and possibly the Lunar/Mars Program. In mid-1989, the FTS entered the flight system design and implementation phase (Phase C/D) of development with the signing of the FTS prime contract with Martin Marietta Astronautics Group in Denver, Colorado. The basic FTS design is now established and can be reported on in some detail. This paper will describe the FTS flight system design and the rationale for the specific design approaches and component selections. The current state of space technology and the general nature of the FTS task dictate that the FTS be designed with sophisticated teleoperation capabilities for its initial primary operating mode. However, there are technologies, such as advanced computer vision and autonomous planning techniques currently in research and advanced development phases which would greatly enhance the FTS capabilities to perform autonomously in less structured work environments. Therefore, a specific requirement on the initial FTS design is that it has the capability to evolve as new technology becomes available. This paper will describe the FTS design approach for evolution to more autonomous capabilities. Some specific task applications of the FTS and partial automation approaches of these tasks will also be discussed in this paper.

The Space Station Freedom Flight Telerobotic Servicer: the design and evolution of a dexterous space robot.

PubMed

McCain, H G; Andary, J F; Hewitt, D R; Haley, D C

1991-01-01

The Flight Telerobotic Servicer (FTS) Project at the Goddard Space Flight Center is developing an advanced telerobotic system to assist in and reduce crew extravehicular activity (EVA) for Space Station) Freedom (SSF). The FTS will provide a telerobotic capability to the Freedom Station in the early assembly phases of the program and will be employed for assembly, maintenance, and inspection applications throughout the lifetime of the space station. Appropriately configured elements of the FTS will also be employed for robotic manipulation in remote satellite servicing applications and possibly the Lunar/Mars Program. In mid-1989, the FTS entered the flight system design and implementation phase (Phase C/D) of development with the signing of the FTS prime contract with Martin Marietta Astronautics Group in Denver, Colorado. The basic FTS design is now established and can be reported on in some detail. This paper will describe the FTS flight system design and the rationale for the specific design approaches and component selections. The current state of space technology and the nature of the FTS task dictate that the FTS be designed with sophisticated teleoperation capabilities for its initial primary operating mode. However, there are technologies, such as advanced computer vision and autonomous planning techniques currently in research and advanced development phases which would greatly enhance the FTS capabilities to perform autonomously in less structured work environments. Therefore, a specific requirement on the initial FTS design is that it has the capability to evolve as new technology becomes available. This paper will describe the FTS design approach for evolution to more autonomous capabilities. Some specific task applications of the FTS and partial automation approaches of these tasks will also be discussed in this paper.

The Space Station Freedom Flight Telerobotic Servicer: the design and evolution of a dexterous space robot

NASA Technical Reports Server (NTRS)

McCain, H. G.; Andary, J. F.; Hewitt, D. R.; Haley, D. C.

1991-01-01

The Flight Telerobotic Servicer (FTS) Project at the Goddard Space Flight Center is developing an advanced telerobotic system to assist in and reduce crew extravehicular activity (EVA) for Space Station) Freedom (SSF). The FTS will provide a telerobotic capability to the Freedom Station in the early assembly phases of the program and will be employed for assembly, maintenance, and inspection applications throughout the lifetime of the space station. Appropriately configured elements of the FTS will also be employed for robotic manipulation in remote satellite servicing applications and possibly the Lunar/Mars Program. In mid-1989, the FTS entered the flight system design and implementation phase (Phase C/D) of development with the signing of the FTS prime contract with Martin Marietta Astronautics Group in Denver, Colorado. The basic FTS design is now established and can be reported on in some detail. This paper will describe the FTS flight system design and the rationale for the specific design approaches and component selections. The current state of space technology and the nature of the FTS task dictate that the FTS be designed with sophisticated teleoperation capabilities for its initial primary operating mode. However, there are technologies, such as advanced computer vision and autonomous planning techniques currently in research and advanced development phases which would greatly enhance the FTS capabilities to perform autonomously in less structured work environments. Therefore, a specific requirement on the initial FTS design is that it has the capability to evolve as new technology becomes available. This paper will describe the FTS design approach for evolution to more autonomous capabilities. Some specific task applications of the FTS and partial automation approaches of these tasks will also be discussed in this paper.

Space station structures and dynamics test program

NASA Technical Reports Server (NTRS)

Moore, Carleton J.; Townsend, John S.; Ivey, Edward W.

1987-01-01

The design, construction, and operation of a low-Earth orbit space station poses unique challenges for development and implementation of new technology. The technology arises from the special requirement that the station be built and constructed to function in a weightless environment, where static loads are minimal and secondary to system dynamics and control problems. One specific challenge confronting NASA is the development of a dynamics test program for: (1) defining space station design requirements, and (2) identifying the characterizing phenomena affecting the station's design and development. A general definition of the space station dynamic test program, as proposed by MSFC, forms the subject of this report. The test proposal is a comprehensive structural dynamics program to be launched in support of the space station. The test program will help to define the key issues and/or problems inherent to large space structure analysis, design, and testing. Development of a parametric data base and verification of the math models and analytical analysis tools necessary for engineering support of the station's design, construction, and operation provide the impetus for the dynamics test program. The philosophy is to integrate dynamics into the design phase through extensive ground testing and analytical ground simulations of generic systems, prototype elements, and subassemblies. On-orbit testing of the station will also be used to define its capability.

Benchmarking CRISPR on-target sgRNA design.

PubMed

Yan, Jifang; Chuai, Guohui; Zhou, Chi; Zhu, Chenyu; Yang, Jing; Zhang, Chao; Gu, Feng; Xu, Han; Wei, Jia; Liu, Qi

2017-02-15

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-based gene editing has been widely implemented in various cell types and organisms. A major challenge in the effective application of the CRISPR system is the need to design highly efficient single-guide RNA (sgRNA) with minimal off-target cleavage. Several tools are available for sgRNA design, while limited tools were compared. In our opinion, benchmarking the performance of the available tools and indicating their applicable scenarios are important issues. Moreover, whether the reported sgRNA design rules are reproducible across different sgRNA libraries, cell types and organisms remains unclear. In our study, a systematic and unbiased benchmark of the sgRNA predicting efficacy was performed on nine representative on-target design tools, based on six benchmark data sets covering five different cell types. The benchmark study presented here provides novel quantitative insights into the available CRISPR tools. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Analysis and design of a 10 to 30 kW grid-connected solar power system for the JPL fire station and first aid station

NASA Technical Reports Server (NTRS)

Josephs, R. H.

1982-01-01

The design and performance of a modestly sized utility-connected power conditioning system and its supporting photovoltaic collector are described and estimated. Utility preparations and guidelines to conform with the output of a small generating station with that of a large power network are examined.

International Space Station (ISS) Nodes 2/3 Thermal Control System Overview and Design

NASA Technical Reports Server (NTRS)

Clanton, Stephen; Croomes, Scott (Technical Monitor)

2002-01-01

The goals of this viewgraph presentation are to: (1) provide general International Space Station (ISS) Node 2 and 3 information; (2) give an overview of the ISS Thermal Control System (TCS) design, including details on the passive TCS and internal and external TCS; (3) give TCS components examples; and (4) describe the thermal and hydraulic analytical tools.

Space station full-scale docking/berthing mechanisms development

NASA Technical Reports Server (NTRS)

Burns, Gene C.; Price, Harold A.; Buchanan, David B.

1988-01-01

One of the most critical operational functions for the space station is the orbital docking between the station and the STS orbiter. The program to design, fabricate, and test docking/berthing mechanisms for the space station is described. The design reflects space station overall requirements and consists of two mating docking mechanism halves. One half is designed for use on the shuttle orbiter and incorporates capture and energy attenuation systems using computer controlled electromechanical actuators and/or attenuators. The mating half incorporates a flexible feature to allow two degrees of freedom at the module-to-module interface of the space station pressurized habitat volumes. The design concepts developed for the prototype units may be used for the first space station flight hardware.

A Retrieval System for Radioactive Target Materials at the NIF

NASA Astrophysics Data System (ADS)

Krieger, M.; Shibata, K.; Fallica, J.; Henchen, R.; Pogozelski, E.; Padalino, S.; Sangster, T. C.; Suny Collaboration; Laboratory Collaboration

2011-10-01

Currently, solid radioactive material collection from the NIF target chamber is performed via the DIM. The retrieval process takes several hours to complete. To decrease this time for short lived radioisotopes, the Target Materials Retrieval System (TMRS) is being designed to move a radioactive sample from the target chamber to the counting station in less than 50 seconds, using a closed-loop helium filled RaPToRS system. The TMRS consists of three components: the retrieval apparatus, RaPToRS and the counting station. Starting at 0.5 meters from TCC, the sample will move from the vacuum chamber, travel through 60 meters of 10 centimeter diameter RaPToRS tubes, reaching speeds of 10 m/s. The sample will then arrive at the counting station, where it be robotically placed in front of a gamma ray detector. The use of helium will decrease background gamma radiation produced by activated N2 normally found in a pressurized air system. This work was supported in part by the US Department of Energy through the LLE.

Thermal Control Subsystem Design for the Avionics of a Space Station Payload

NASA Technical Reports Server (NTRS)

Moran, Matthew E.

1996-01-01

A case study of the thermal control subsystem development for a space based payload is presented from the concept stage through preliminary design. This payload, the Space Acceleration Measurement System 2 (SAMS-2), will measure the acceleration environment at select locations within the International Space Station. Its thermal control subsystem must maintain component temperatures within an acceptable range over a 10 year life span, while restricting accessible surfaces to touch temperature limits and insuring fail safe conditions in the event of loss of cooling. In addition to these primary design objectives, system level requirements and constraints are imposed on the payload, many of which are driven by multidisciplinary issues. Blending these issues into the overall system design required concurrent design sessions with the project team, iterative conceptual design layouts, thermal analysis and modeling, and hardware testing. Multiple tradeoff studies were also performed to investigate the many options which surfaced during the development cycle.

Space Station: The next iteration

NASA Astrophysics Data System (ADS)

Foley, Theresa M.

1995-01-01

NASA's international space station is nearing the completion stage of its troublesome 10-year design phase. With a revised design and new management team, NASA is tasked to deliver the station on time at a budget acceptable to both Congress and the White House. For the next three years, NASA is using tried-and-tested Russian hardware as the technical centerpiece of the station. The new station configuration consists of eight pressurized modules in which the crew can live and work; a long metal truss to connect the pieces; a robot arm for exterior jobs; a solar power system; and propelling the facility in space.

Designing multi-targeted agents: An emerging anticancer drug discovery paradigm.

PubMed

Fu, Rong-Geng; Sun, Yuan; Sheng, Wen-Bing; Liao, Duan-Fang

2017-08-18

The dominant paradigm in drug discovery is to design ligands with maximum selectivity to act on individual drug targets. With the target-based approach, many new chemical entities have been discovered, developed, and further approved as drugs. However, there are a large number of complex diseases such as cancer that cannot be effectively treated or cured only with one medicine to modulate the biological function of a single target. As simultaneous intervention of two (or multiple) cancer progression relevant targets has shown improved therapeutic efficacy, the innovation of multi-targeted drugs has become a promising and prevailing research topic and numerous multi-targeted anticancer agents are currently at various developmental stages. However, most multi-pharmacophore scaffolds are usually discovered by serendipity or screening, while rational design by combining existing pharmacophore scaffolds remains an enormous challenge. In this review, four types of multi-pharmacophore modes are discussed, and the examples from literature will be used to introduce attractive lead compounds with the capability of simultaneously interfering with different enzyme or signaling pathway of cancer progression, which will reveal the trends and insights to help the design of the next generation multi-targeted anticancer agents. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation†

PubMed Central

Kamaly, Nazila; Xiao, Zeyu; Valencia, Pedro M.; Radovic-Moreno, Aleksandar F.; Farokhzad, Omid C.

2013-01-01

Polymeric materials have been used in a range of pharmaceutical and biotechnology products for more than 40 years. These materials have evolved from their earlier use as biodegradable products such as resorbable sutures, orthopaedic implants, macroscale and microscale drug delivery systems such as microparticles and wafers used as controlled drug release depots, to multifunctional nanoparticles (NPs) capable of targeting, and controlled release of therapeutic and diagnostic agents. These newer generations of targeted and controlled release polymeric NPs are now engineered to navigate the complex in vivo environment, and incorporate functionalities for achieving target specificity, control of drug concentration and exposure kinetics at the tissue, cell, and subcellular levels. Indeed this optimization of drug pharmacology as aided by careful design of multifunctional NPs can lead to improved drug safety and efficacy, and may be complimentary to drug enhancements that are traditionally achieved by medicinal chemistry. In this regard, polymeric NPs have the potential to result in a highly differentiated new class of therapeutics, distinct from the original active drugs used in their composition, and distinct from first generation NPs that largely facilitated drug formulation. A greater flexibility in the design of drug molecules themselves may also be facilitated following their incorporation into NPs, as drug properties (solubility, metabolism, plasma binding, biodistribution, target tissue accumulation) will no longer be constrained to the same extent by drug chemical composition, but also become in-part the function of the physicochemical properties of the NP. The combination of optimally designed drugs with optimally engineered polymeric NPs opens up the possibility of improved clinical outcomes that may not be achievable with the administration of drugs in their conventional form. In this critical review, we aim to provide insights into the design and development

The Princess Elisabeth Station

NASA Technical Reports Server (NTRS)

Berte, Johan

2012-01-01

Aware of the increasing impact of human activities on the Earth system, Belgian Science Policy Office (Belspo) launched in 1997 a research programme in support of a sustainable development policy. This umbrella programme included the Belgian Scientific Programme on Antarctic Research. The International Polar Foundation, an organization led by the civil engineer and explorer Alain Hubert, was commissioned by the Belgian Federal government in 2004 to design, construct and operate a new Belgian Antarctic Research Station as an element under this umbrella programme. The station was to be designed as a central location for investigating the characteristic sequence of Antarctic geographical regions (polynia, coast, ice shelf, ice sheet, marginal mountain area and dry valleys, inland plateau) within a radius of 200 kilometers (approx.124 miles) of a selected site. The station was also to be designed as "state of the art" with respect to sustainable development, energy consumption, and waste disposal, with a minimum lifetime of 25 years. The goal of the project was to build a station and enable science. So first we needed some basic requirements, which I have listed here; plus we had to finance the station ourselves. Our most important requirement was that we decided to make it a zero emissions station. This was both a philosophical choice as we thought it more consistent with Antarctic Treaty obligations and it was also a logistical advantage. If you are using renewable energy sources, you do not have to bring in all the fuel.

Massively parallel de novo protein design for targeted therapeutics.

PubMed

Chevalier, Aaron; Silva, Daniel-Adriano; Rocklin, Gabriel J; Hicks, Derrick R; Vergara, Renan; Murapa, Patience; Bernard, Steffen M; Zhang, Lu; Lam, Kwok-Ho; Yao, Guorui; Bahl, Christopher D; Miyashita, Shin-Ichiro; Goreshnik, Inna; Fuller, James T; Koday, Merika T; Jenkins, Cody M; Colvin, Tom; Carter, Lauren; Bohn, Alan; Bryan, Cassie M; Fernández-Velasco, D Alejandro; Stewart, Lance; Dong, Min; Huang, Xuhui; Jin, Rongsheng; Wilson, Ian A; Fuller, Deborah H; Baker, David

2017-10-05

De novo protein design holds promise for creating small stable proteins with shapes customized to bind therapeutic targets. We describe a massively parallel approach for designing, manufacturing and screening mini-protein binders, integrating large-scale computational design, oligonucleotide synthesis, yeast display screening and next-generation sequencing. We designed and tested 22,660 mini-proteins of 37-43 residues that target influenza haemagglutinin and botulinum neurotoxin B, along with 6,286 control sequences to probe contributions to folding and binding, and identified 2,618 high-affinity binders. Comparison of the binding and non-binding design sets, which are two orders of magnitude larger than any previously investigated, enabled the evaluation and improvement of the computational model. Biophysical characterization of a subset of the binder designs showed that they are extremely stable and, unlike antibodies, do not lose activity after exposure to high temperatures. The designs elicit little or no immune response and provide potent prophylactic and therapeutic protection against influenza, even after extensive repeated dosing.

Massively parallel de novo protein design for targeted therapeutics

NASA Astrophysics Data System (ADS)

Chevalier, Aaron; Silva, Daniel-Adriano; Rocklin, Gabriel J.; Hicks, Derrick R.; Vergara, Renan; Murapa, Patience; Bernard, Steffen M.; Zhang, Lu; Lam, Kwok-Ho; Yao, Guorui; Bahl, Christopher D.; Miyashita, Shin-Ichiro; Goreshnik, Inna; Fuller, James T.; Koday, Merika T.; Jenkins, Cody M.; Colvin, Tom; Carter, Lauren; Bohn, Alan; Bryan, Cassie M.; Fernández-Velasco, D. Alejandro; Stewart, Lance; Dong, Min; Huang, Xuhui; Jin, Rongsheng; Wilson, Ian A.; Fuller, Deborah H.; Baker, David

2017-10-01

De novo protein design holds promise for creating small stable proteins with shapes customized to bind therapeutic targets. We describe a massively parallel approach for designing, manufacturing and screening mini-protein binders, integrating large-scale computational design, oligonucleotide synthesis, yeast display screening and next-generation sequencing. We designed and tested 22,660 mini-proteins of 37-43 residues that target influenza haemagglutinin and botulinum neurotoxin B, along with 6,286 control sequences to probe contributions to folding and binding, and identified 2,618 high-affinity binders. Comparison of the binding and non-binding design sets, which are two orders of magnitude larger than any previously investigated, enabled the evaluation and improvement of the computational model. Biophysical characterization of a subset of the binder designs showed that they are extremely stable and, unlike antibodies, do not lose activity after exposure to high temperatures. The designs elicit little or no immune response and provide potent prophylactic and therapeutic protection against influenza, even after extensive repeated dosing.

Massively parallel de novo protein design for targeted therapeutics

PubMed Central

Chevalier, Aaron; Silva, Daniel-Adriano; Rocklin, Gabriel J.; Hicks, Derrick R.; Vergara, Renan; Murapa, Patience; Bernard, Steffen M.; Zhang, Lu; Lam, Kwok-Ho; Yao, Guorui; Bahl, Christopher D.; Miyashita, Shin-Ichiro; Goreshnik, Inna; Fuller, James T.; Koday, Merika T.; Jenkins, Cody M.; Colvin, Tom; Carter, Lauren; Bohn, Alan; Bryan, Cassie M.; Fernández-Velasco, D. Alejandro; Stewart, Lance; Dong, Min; Huang, Xuhui; Jin, Rongsheng; Wilson, Ian A.; Fuller, Deborah H.; Baker, David

2018-01-01

De novo protein design holds promise for creating small stable proteins with shapes customized to bind therapeutic targets. We describe a massively parallel approach for designing, manufacturing and screening mini-protein binders, integrating large-scale computational design, oligonucleotide synthesis, yeast display screening and next-generation sequencing. We designed and tested 22,660 mini-proteins of 37–43 residues that target influenza haemagglutinin and botulinum neurotoxin B, along with 6,286 control sequences to probe contributions to folding and binding, and identified 2,618 high-affinity binders. Comparison of the binding and non-binding design sets, which are two orders of magnitude larger than any previously investigated, enabled the evaluation and improvement of the computational model. Biophysical characterization of a subset of the binder designs showed that they are extremely stable and, unlike antibodies, do not lose activity after exposure to high temperatures. The designs elicit little or no immune response and provide potent prophylactic and therapeutic protection against influenza, even after extensive repeated dosing. PMID:28953867

Astrophysical payload accommodation on the space station

NASA Technical Reports Server (NTRS)

Woods, B. P.

1985-01-01

Surveys of potential space station astrophysics payload requirements and existing point mount design concepts were performed to identify potential design approaches for accommodating astrophysics instruments from space station. Most existing instrument pointing systems were designed for operation from the space shuttle and it is unlikely that they will sustain their performance requirements when exposed to the space station disturbance environment. The technology exists or is becoming available so that precision pointing can be provided from the space station manned core. Development of a disturbance insensitive pointing mount is the key to providing a generic system for space station. It is recommended that the MSFC Suspended Experiment Mount concept be investigated for use as part of a generic pointing mount for space station. Availability of a shirtsleeve module for instrument change out, maintenance and repair is desirable from the user's point of view. Addition of a shirtsleeve module on space station would require a major program commitment.

DESIGNING AN OPPORTUNITY FUEL WITH BIOMASS AND TIRE-DERIVED FUEL FOR COFIRING AT WILLOW ISLAND GENERATING STATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

K. Payette; D. Tillman

During the period January 1, 2001-March 31, 2001, Allegheny Energy Supply Co., LLC (Allegheny) finalized the engineering of the Willow Island cofiring project, completed the fuel characterizations for both the Willow Island and Albright Generating Station projects, and initiated construction of both projects. Allegheny and its contractor, Foster Wheeler, selected appropriate fuel blends and issued purchase orders for all processing and mechanical equipment to be installed at both sites. This report summarizes the activities associated with the Designer Opportunity Fuel program, and demonstrations at Willow Island and Albright Generating Stations. The third quarter of the project involved completing the detailedmore » designs for the Willow Island Designer Fuel project. It also included complete characterization of the coal and biomass fuels being burned, focusing upon the following characteristics: proximate and ultimate analysis; higher heating value; carbon 13 nuclear magnetic resonance testing for aromaticity, number of aromatic carbons per cluster, and the structural characteristics of oxygen in the fuel; drop tube reactor testing for high temperature devolatilization kinetics and generation of fuel chars; thermogravimetric analyses (TGA) for char oxidation kinetics; and related testing. The construction at both sites commenced during this quarter, and was largely completed at the Albright Generating Station site.« less

49 CFR 37.49 - Designation of responsible person(s) for intercity and commuter rail stations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Designation of responsible person(s) for intercity and commuter rail stations. 37.49 Section 37.49 Transportation Office of the Secretary of Transportation TRANSPORTATION SERVICES FOR INDIVIDUALS WITH DISABILITIES (ADA) Transportation Facilities § 37.49...

Flywheel Energy Storage System Designed for the International Space Station

NASA Technical Reports Server (NTRS)

Delventhal, Rex A.

2002-01-01

Following successful operation of a developmental flywheel energy storage system in fiscal year 2000, researchers at the NASA Glenn Research Center began developing a flight design of a flywheel system for the International Space Station (ISS). In such an application, a two-flywheel system can replace one of the nickel-hydrogen battery strings in the ISS power system. The development unit, sized at approximately one-eighth the size needed for ISS was run at 60,000 rpm. The design point for the flight unit is a larger composite flywheel, approximately 17 in. long and 13 in. in diameter, running at 53,000 rpm when fully charged. A single flywheel system stores 2.8 kW-hr of useable energy, enough to light a 100-W light bulb for over 24 hr. When housed in an ISS orbital replacement unit, the flywheel would provide energy storage with approximately 3 times the service life of the nickel-hydrogen battery currently in use.

Space Station crew workload - Station operations and customer accommodations

NASA Technical Reports Server (NTRS)

Shinkle, G. L.

1985-01-01

The features of the Space Station which permit crew members to utilize work time for payload operations are discussed. The user orientation, modular design, nonstressful flight regime, in space construction, on board control, automation and robotics, and maintenance and servicing of the Space Station are examined. The proposed crew size, skills, and functions as station operator and mission specialists are described. Mission objectives and crew functions, which include performing material processing, life science and astronomy experiments, satellite and payload equipment servicing, systems monitoring and control, maintenance and repair, Orbital Maneuvering Vehicle and Mobile Remote Manipulator System operations, on board planning, housekeeping, and health maintenance and recreation, are studied.

Validation of an Integrated Hydrogen Energy Station

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heydorn, Edward C

This report presents the results of a 10-year project conducted by Air Products and Chemicals, Inc. (Air Products) to determine the feasibility of coproducing hydrogen with electricity. The primary objective was to demonstrate the technical and economic viability of a hydrogen energy station using a high-temperature fuel cell designed to produce power and hydrogen. This four-phase project had intermediate go/no-go decisions and the following specific goals: Complete a technical assessment and economic analysis of the use of high-temperature fuel cells, including solid oxide and molten carbonate, for the co-production of power and hydrogen (energy park concept). Build on the experiencemore » gained at the Las Vegas H2 Energy Station and compare/contrast the two approaches for co-production. Determine the applicability of co-production from a high-temperature fuel cell for the existing merchant hydrogen market and for the emerging hydrogen economy. Demonstrate the concept on natural gas for six months at a suitable site with demand for both hydrogen and electricity. Maintain safety as the top priority in the system design and operation. Obtain adequate operational data to provide the basis for future commercial activities, including hydrogen fueling stations. Work began with the execution of the cooperative agreement with DOE on 30 September 2001. During Phase 1, Air Products identified high-temperature fuel cells as having the potential to meet the coproduction targets, and the molten carbonate fuel cell system from FuelCell Energy, Inc. (FuelCell Energy) was selected by Air Products and DOE following the feasibility assessment performed during Phase 2. Detailed design, construction and shop validation testing of a system to produce 250 kW of electricity and 100 kilograms per day of hydrogen, along with site selection to include a renewable feedstock for the fuel cell, were completed in Phase 3. The system also completed six months of demonstration operation at

Work/control stations in Space Station weightlessness

NASA Technical Reports Server (NTRS)

Willits, Charles

1990-01-01

An ergonomic integration of controls, displays, and associated interfaces with an operator, whose body geometry and dynamics may be altered by the state of weightlessness, is noted to rank in importance with the optimal positioning of controls relative to the layout and architecture of 'body-ported' work/control stations applicable to the NASA Space Station Freedom. A long-term solution to this complex design problem is envisioned to encompass the following features: multiple imaging, virtual optics, screen displays controlled by a keyboard ergonomically designed for weightlessness, cursor control, a CCTV camera, and a hand-controller featuring 'no-grip' vernier/tactile positioning. This controller frees all fingers for multiple-switch actuations, while retaining index/register determination with the hand controller. A single architectural point attachment/restraint may be used which requires no residual muscle tension in either brief or prolonged operation.

Space Station fluid resupply

NASA Technical Reports Server (NTRS)

Winters, AL

1990-01-01

Viewgraphs on space station fluid resupply are presented. Space Station Freedom is resupplied with supercritical O2 and N2 for the ECLSS and USL on a 180 day resupply cycle. Resupply fluids are stored in the subcarriers on station between resupply cycles and transferred to the users as required. ECLSS contingency fluids (O2 and N2) are supplied and stored on station in a gaseous state. Efficiency and flexibility are major design considerations. Subcarrier approach allows multiple manifest combinations. Growth is achieved by adding modular subcarriers.

Incorporation of privacy elements in space station design

NASA Technical Reports Server (NTRS)

Harrison, Albert A.; Caldwell, Barrett; Struthers, Nancy J.

1988-01-01

Privacy exists to the extent that individuals can control the degree of social contact that they have with one another. The opportunity to withdraw from other people serves a number of important psychological and social functions, and is in the interests of safety, high performance, and high quality of human life. Privacy requirements for Space Station crew members are reviewed, and architectual and other guidelines for helping astronauts achieve desired levels of privacy are suggested. In turn, four dimensions of privacy are discussed: the separation of activities by areas within the Space Station, controlling the extent to which astronauts have visual contact with one another, controlling the extent to which astronauts have auditory contact with one another, and odor control. Each section presents a statement of the problem, a review of general solutions, and specific recommendations. The report is concluded with a brief consideration of how selection, training, and other procedures can also help Space Station occupants achieve satisfactory levels of seclusion.

Conceptual design for the space station Freedom modular combustion facility

NASA Technical Reports Server (NTRS)

1989-01-01

A definition study and conceptual design for a combustion science facility that will be located in the Space Station Freedom's baseline U.S. Laboratory module is being performed. This modular, user-friendly facility, called the Modular Combustion Facility, will be available for use by industry, academic, and government research communities in the mid-1990's. The Facility will support research experiments dealing with the study of combustion and its byproducts. Because of the lack of gravity-induced convection, research into the mechanisms of combustion in the absence of gravity will help to provide a better understanding of the fundamentals of the combustion process. The background, current status, and future activities of the effort are covered.

Alkaline RFC Space Station prototype - 'Next step Space Station'. [Regenerative Fuel Cells

NASA Technical Reports Server (NTRS)

Hackler, I. M.

1986-01-01

The regenerative fuel cell, a candidate technology for the Space Station's energy storage system, is described. An advanced development program was initiated to design, manufacture, and integrate a regenerative fuel cell Space Station prototype (RFC SSP). The RFC SSP incorporates long-life fuel cell technology, increased cell area for the fuel cells, and high voltage cell stacks for both units. The RFC SSP's potential for integration with the Space Station's life support and propulsion systems is discussed.

47 CFR 97.211 - Space telecommand station.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 5 2014-10-01 2014-10-01 false Space telecommand station. 97.211 Section 97... AMATEUR RADIO SERVICE Special Operations § 97.211 Space telecommand station. (a) Any amateur station designated by the licensee of a space station is eligible to transmit as a telecommand station for that space...

47 CFR 97.211 - Space telecommand station.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 5 2013-10-01 2013-10-01 false Space telecommand station. 97.211 Section 97... AMATEUR RADIO SERVICE Special Operations § 97.211 Space telecommand station. (a) Any amateur station designated by the licensee of a space station is eligible to transmit as a telecommand station for that space...

47 CFR 97.211 - Space telecommand station.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false Space telecommand station. 97.211 Section 97... AMATEUR RADIO SERVICE Special Operations § 97.211 Space telecommand station. (a) Any amateur station designated by the licensee of a space station is eligible to transmit as a telecommand station for that space...

47 CFR 97.211 - Space telecommand station.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 47 Telecommunication 5 2012-10-01 2012-10-01 false Space telecommand station. 97.211 Section 97... AMATEUR RADIO SERVICE Special Operations § 97.211 Space telecommand station. (a) Any amateur station designated by the licensee of a space station is eligible to transmit as a telecommand station for that space...

47 CFR 97.211 - Space telecommand station.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 5 2011-10-01 2011-10-01 false Space telecommand station. 97.211 Section 97... AMATEUR RADIO SERVICE Special Operations § 97.211 Space telecommand station. (a) Any amateur station designated by the licensee of a space station is eligible to transmit as a telecommand station for that space...

DESIGNING AN OPPORTUNITY FUEL WITH BIOMASS AND TIRE-DERIVED FUEL FOR COFIRING AT WILLOW ISLAND GENERATING STATION AND COFIRING SAWDUST WITH COAL AT ALBRIGHT GENERATING STATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

K. Payette; D. Tillman

During the period July 1, 2001--September 30, 2001, Allegheny Energy Supply Co., LLC (Allegheny) continued construction of the Willow Island cofiring project, completed the installation of the fuel storage facility, the fuel receiving facility, and the processing building. All mechanical equipment has been installed and electrical construction has proceeded. During this time period significant short term testing of the Albright Generating Station cofiring facility was completed, and the 100-hour test was planned for early October. The testing demonstrated that cofiring at the Albright Generating Station could contribute to a ''4P Strategy''--reduction of SO{sub 2}, NO{sub x}, mercury, and greenhouse gasmore » emissions. This report summarizes the activities associated with the Designer Opportunity Fuel program, and demonstrations at Willow Island and Albright Generating Stations. It details the construction activities at both sites along with the combustion modeling at the Willow Island site.« less

Space station executive summary

NASA Technical Reports Server (NTRS)

1972-01-01

An executive summary of the modular space station study is presented. The subjects discussed are: (1) design characteristics, (2) experiment program, (3) operations, (4) program description, and (5) research implications. The modular space station is considered a candidate payload for the low cost shuttle transportation system.

Crew interface with a telerobotic control station

NASA Technical Reports Server (NTRS)

Mok, Eva

1987-01-01

A method for apportioning crew-telerobot tasks has been derived to facilitate the design of a crew-friendly telerobot control station. To identify the most appropriate state-of-the-art hardware for the control station, task apportionment must first be conducted to identify if an astronaut or a telerobot is best to execute the task and which displays and controls are required for monitoring and performance. Basic steps that comprise the task analysis process are: (1) identify space station tasks; (2) define tasks; (3) define task performance criteria and perform task apportionment; (4) verify task apportionment; (5) generate control station requirements; (6) develop design concepts to meet requirements; and (7) test and verify design concepts.

Space Station fluid management logistics

NASA Technical Reports Server (NTRS)

Dominick, Sam M.

1990-01-01

Viewgraphs and discussion on space station fluid management logistics are presented. Topics covered include: fluid management logistics - issues for Space Station Freedom evolution; current fluid logistics approach; evolution of Space Station Freedom fluid resupply; launch vehicle evolution; ELV logistics system approach; logistics carrier configuration; expendable fluid/propellant carrier description; fluid carrier design concept; logistics carrier orbital operations; carrier operations at space station; summary/status of orbital fluid transfer techniques; Soviet progress tanker system; and Soviet propellant resupply system observations.

International Space Station (ISS)

NASA Image and Video Library

1998-11-08

Designed by the STS-88 crew members, this patch commemorates the first assembly flight to carry United States-built hardware for constructing the International Space Station (ISS). This flight's primary task was to assemble the cornerstone of the Space Station: the Node with the Functional Cargo Block (FGB). The rising sun symbolizes the dawning of a new era of international cooperation in space and the beginning of a new program: the International Space Station. The Earth scene outlines the countries of the Station Partners: the United States, Russia, those of the European Space Agency (ESA), Japan, and Canada. Along with the Pressurized Mating Adapters (PMA) and the Functional Cargo Block, the Node is shown in the final mated configuration while berthed to the Space Shuttle during the STS-88/2A mission. The Big Dipper Constellation points the way to the North Star, a guiding light for pioneers and explorers for generations. In the words of the crew, These stars symbolize the efforts of everyone, including all the countries involved in the design and construction of the International Space Station, guiding us into the future.

DESIGNING AN OPPORTUNITY FUEL WITH BIOMASS AND TIRE-DERIVED FUEL FOR COFIRING AT WILLOW ISLAND GENERATING STATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

K. Payette; D. Tillman

During the period October 1, 2000 - December 31, 2000, Allegheny Energy Supply Co., LLC (Allegheny) executed a Cooperative Agreement with the National Energy Technology Laboratory to implement a major cofiring demonstration at the Willow Island Generating Station Boiler No.2. Willow Island Boiler No.2 is a cyclone boiler. Allegheny also will demonstrate separate injection cofiring at the Albright Generating Station Boiler No.3, a tangentially fired boiler. The Allegheny team includes Foster Wheeler as its primary subcontractor. Additional subcontractors are Cofiring Alternatives and N.S. Harding and Associates. This report summarizes the activities associated with the Designer Opportunity Fuel program, and demonstrationsmore » at Willow Island and Albright Generating Stations. The second quarter of the project involved completing the designs for each location. Further, geotechnical investigations proceeded at each site. Preparations were made to perform demolition on two small buildings at the Willow Island site. Fuels strategies were initiated for each site. Test planning commenced for each site. A groundbreaking ceremony was held at the Willow Island site on October 18, with Governor C. Underwood being the featured speaker.« less

Applicability of ASST-A helium refrigeration system for JLab End Station Refrigerator

NASA Astrophysics Data System (ADS)

Hasan, N.; Knudsen, P.; Ganni, V.

2017-12-01

The MØLLER experiment at Jefferson Lab (JLab) is a high power (5 kW) liquid hydrogen target scheduled to be operational in the 12 GeV-era. At present, cryogenic loads and targets at three of JLab’s four experimental halls are supported by the End Station Refrigerator (ESR) - a CTI/Helix 1.5 kW 4.5 K refrigerator. It is not capable of supporting the high power target load and a capacity upgrade of the ESR cryogenic system is essential. The ASST-A helium refrigeration system is a 4 kW 4.5 K refrigerator. It was designed and used for the Superconducting Super Collider Lab (SSCL) magnet string test and later obtained by JLab after the cancellation of that project. The modified ASST-A refrigeration system, which will be called ESR-II along with a support flow from JLab’s Central Helium Liquefier (CHL) is considered as an option for the End Station Refrigerator capacity upgrade. The applicability of this system for ESR-II under varying load conditions is investigated. The present paper outlines the findings of this process study.

Proposal for a remotely manned space station

NASA Technical Reports Server (NTRS)

Minsky, Marvin

1990-01-01

The United States is in trouble in space. The costs of the proposed Space Station Freedom have grown beyond reach, and the present design is obsolete. The trouble has come from imagining that there are only two alternatives: manned vs. unmanned. Both choices have led us into designs that do not appear to be practical. On one side, the United States simply does not possess the robotic technology needed to operate or assemble a sophisticated unmanned space station. On the other side, the manned designs that are now under way seem far too costly and dangerous, with all of its thousands of extravehicular activity (EVA) hours. More would be accomplished at far less cost by proceeding in a different way. The design of a space station made of modular, Erector Set-like parts is proposed which is to be assembled using earth-based remotely-controlled binary-tree telerobots. Earth-based workers could be trained to build the station in space using simulators. A small preassembled spacecraft would be launched with a few telerobots, and then, telerobots could be ferried into orbit along with stocks of additional parts. Trained terrestrial workers would remotely assemble a larger station, and materials for additional power and life support systems could be launched. Finally, human scientists and explorers could be sent to the space station. Other aspects of such a space station program are discussed.

Autonomous Rover Traverse and Precise Arm Placement on Remotely Designated Targets

NASA Technical Reports Server (NTRS)

Nesnas, Issa A.; Pivtoraiko, Mihail N.; Kelly, Alonzo; Fleder, Michael

2012-01-01

This software controls a rover platform to traverse rocky terrain autonomously, plan paths, and avoid obstacles using its stereo hazard and navigation cameras. It does so while continuously tracking a target of interest selected from 10 20 m away. The rover drives and tracks the target until it reaches the vicinity of the target. The rover then positions itself to approach the target, deploys its robotic arm, and places the end effector instrument on the designated target to within 2-3-cm accuracy of the originally selected target. This software features continuous navigation in a fairly rocky field in an outdoor environment and the ability to enable the rover to avoid large rocks and traverse over smaller ones. Using point-and-click mouse commands, a scientist designates targets in the initial imagery acquired from the rover s mast cameras. The navigation software uses stereo imaging, traversability analysis, path planning, trajectory generation, and trajectory execution. It also includes visual target tracking of a designated target selected from 10 m away while continuously navigating the rocky terrain. Improvements in this design include steering while driving, which uses continuous curvature paths. There are also several improvements to the traversability analyzer, including improved data fusion of traversability maps that result from pose estimation uncertainties, dealing with boundary effects to enable tighter maneuvers, and handling a wider range of obstacles. This work advances what has been previously developed and integrated on the Mars Exploration Rovers by using algorithms that are capable of traversing more rock-dense terrains, enabling tight, thread-the-needle maneuvers. These algorithms were integrated on the newly refurbished Athena Mars research rover, and were fielded in the JPL Mars Yard. Forty-three runs were conducted with targets at distances ranging from 5 to 15 m, and a success rate of 93% was achieved for placement of the instrument within

Autonomous Rover Traverse and Precise Arm Placement on Remotely Designated Targets

NASA Technical Reports Server (NTRS)

Felder, Michael; Nesnas, Issa A.; Pivtoraiko, Mihail; Kelly, Alonzo; Volpe, Richard

2011-01-01

Exploring planetary surfaces typically involves traversing challenging and unknown terrain and acquiring in-situ measurements at designated locations using arm-mounted instruments. We present field results for a new implementation of an autonomous capability that enables a rover to traverse and precisely place an arm-mounted instrument on remote targets. Using point-and-click mouse commands, a scientist designates targets in the initial imagery acquired from the rover's mast cameras. The rover then autonomously traverse the rocky terrain for a distance of 10 - 15 m, tracks the target(s) of interest during the traverse, positions itself for approaching the target, and then precisely places an arm-mounted instrument within 2-3 cm from the originally designated target. The rover proceeds to acquire science measurements with the instrument. This work advances what has been previously developed and integrated on the Mars Exploration Rovers by using algorithms that are capable of traversing more rock-dense terrains, enabling tight thread-the-needle maneuvers. We integrated these algorithms on the newly refurbished Athena Mars research rover and fielded them in the JPL Mars Yard. We conducted 43 runs with targets at distances ranging from 5 m to 15 m and achieved a success rate of 93% for placement of the instrument within 2-3 cm.

An investigation of the needs and the design of an orbiting space station with growth capabilities

NASA Technical Reports Server (NTRS)

Dossey, J. R.; Trotti, G.

1977-01-01

An architectural approach to the evolutionary growth of an orbiting space station from a small manned satellite to a fully independent, self-sustainable space colony facility is presented. Social and environmental factors, ease of transportation via the space shuttle, and structural design are considered.

Design of a 12 channel fm microwave receiver. [for satellite ground stations

NASA Technical Reports Server (NTRS)

Risch, C. O.; Rosenbaum, F. J.; Gregory, R. O.

1974-01-01

The design, fabrication, and performance of elements of a low cost FM microwave satellite ground station receiver is described. It is capable of accepting 12 contiguous color television equivalent bandwidth channels in the 11.72 to 12.2 GHz band. Each channel is 40 MHz wide and incorporates a 4 MHz guard band. The modulation format is wideband FM and the channels are frequency division multiplexed. Twelve independent CATV compatible baseband outputs are provided. The overall system specifications are first discussed, then consideration is given to the receiver subsystems and the signal branching network.

Regenerative fuel cell systems for space station

NASA Technical Reports Server (NTRS)

Hoberecht, M. A.; Sheibley, D. W.

1985-01-01

Regenerative fuel cell (RFC) systems are the leading energy storage candidates for Space Station. Key design features are the advanced state of technology readiness and high degree of system level design flexibility. Technology readiness was demonstrated through testing at the single cell, cell stack, mechanical ancillary component, subsystem, and breadboard levels. Design flexibility characteristics include independent sizing of power and energy storage portions of the system, integration of common reactants with other space station systems, and a wide range of various maintenance approaches. The design features led to selection of a RFC system as the sole electrochemical energy storage technology option for the space station advanced development program.

An automated rendezvous and capture system design concept for the cargo transfer vehicle and Space Station Freedom

NASA Technical Reports Server (NTRS)

Fuchs, Ron; Marsh, Steven

1991-01-01

A rendezvous sensor system concept was developed for the cargo transfer vehicle (CTV) to autonomously rendezvous with and be captured by Space Station Freedom (SSF). The development of requirements, the design of a unique Lockheed developed sensor concept to meet these requirements, and the system design to place this sensor on the CTV and rendezvous with the SSF are described .

Space Station Freedom operations costs

NASA Technical Reports Server (NTRS)

Accola, Anne L.; Williams, Gregory J.

1988-01-01

Measures to reduce the operation costs of the Space Station which can be implemented in the design and development stages are discussed. Operational functions are described in the context of an overall operations concept. The provisions for operations cost responsibilities among the partners in the Space Station program are presented. Cost estimating methodologies and the way in which operations costs affect the design and development process are examined.

Selection and trajectory design to mission secondary targets

NASA Astrophysics Data System (ADS)

Victorino Sarli, Bruno; Kawakatsu, Yasuhiro

2017-02-01

Recently, with new trajectory design techniques and use of low-thrust propulsion systems, missions have become more efficient and cheaper with respect to propellant. As a way to increase the mission's value and scientific return, secondary targets close to the main trajectory are often added with a small change in the transfer trajectory. As a result of their large number, importance and facility to perform a flyby, asteroids are commonly used as such targets. This work uses the Primer Vector theory to define the direction and magnitude of the thrust for a minimum fuel consumption problem. The design of a low-thrust trajectory with a midcourse asteroid flyby is not only challenging for the low-thrust problem solution, but also with respect to the selection of a target and its flyby point. Currently more than 700,000 minor bodies have been identified, which generates a very large number of possible flyby points. This work uses a combination of reachability, reference orbit, and linear theory to select appropriate candidates, drastically reducing the simulation time, to be later included in the main trajectory and optimized. Two test cases are presented using the aforementioned selection process and optimization to add and design a secondary flyby to a mission with the primary objective of 3200 Phaethon flyby and 25143 Itokawa rendezvous.

Space station functional relationships analysis

NASA Technical Reports Server (NTRS)

Tullis, Thomas S.; Bied, Barbra R.

1988-01-01

A systems engineering process is developed to assist Space Station designers to understand the underlying operational system of the facility so that it can be physically arranged and configured to support crew productivity. The study analyzes the operational system proposed for the Space Station in terms of mission functions, crew activities, and functional relationships in order to develop a quantitative model for evaluation of interior layouts, configuration, and traffic analysis for any Station configuration. Development of the model involved identification of crew functions, required support equipment, criteria of assessing functional relationships, and tools for analyzing functional relationship matrices, as well as analyses of crew transition frequency, sequential dependencies, support equipment requirements, potential for noise interference, need for privacy, and overall compatability of functions. The model can be used for analyzing crew functions for the Initial Operating Capability of the Station and for detecting relationships among these functions. Note: This process (FRA) was used during Phase B design studies to test optional layouts of the Space Station habitat module. The process is now being automated as a computer model for use in layout testing of the Space Station laboratory modules during Phase C.

Crew considerations in the design for Space Station Freedom modules on-orbit maintenance

NASA Technical Reports Server (NTRS)

Stokes, Jack W.; Williams, Katherine A.

1992-01-01

The paper presents an approach to the maintenance process currently planned for the Space Station Freedom modules. In particular, it describes the planned crew interfaces with maintenance items, and the anticipated implications for the crew in performing the interior and exterior maintenance of modules developed by U.S., ESA, and NASDA. Special consideration is given to the maintenance requirements, allocations, and approach; the maintenance design; the Maintenance Workstation; the robotic mechanisms; and the developemnt of maintenance techniques.

Single-Station Sigma for the Iranian Strong Motion Stations

NASA Astrophysics Data System (ADS)

Zafarani, H.; Soghrat, M. R.

2017-11-01

In development of ground motion prediction equations (GMPEs), the residuals are assumed to have a log-normal distribution with a zero mean and a standard deviation, designated as sigma. Sigma has significant effect on evaluation of seismic hazard for designing important infrastructures such as nuclear power plants and dams. Both aleatory and epistemic uncertainties are involved in the sigma parameter. However, ground-motion observations over long time periods are not available at specific sites and the GMPEs have been derived using observed data from multiple sites for a small number of well-recorded earthquakes. Therefore, sigma is dominantly related to the statistics of the spatial variability of ground motion instead of temporal variability at a single point (ergodic assumption). The main purpose of this study is to reduce the variability of the residuals so as to handle it as epistemic uncertainty. In this regard, it is tried to partially apply the non-ergodic assumption by removing repeatable site effects from total variability of six GMPEs driven from the local, Europe-Middle East and worldwide data. For this purpose, we used 1837 acceleration time histories from 374 shallow earthquakes with moment magnitudes ranging from M w 4.0 to 7.3 recorded at 370 stations with at least two recordings per station. According to estimated single-station sigma for the Iranian strong motion stations, the ratio of event-corrected single-station standard deviation ( Φ ss) to within-event standard deviation ( Φ) is about 0.75. In other words, removing the ergodic assumption on site response resulted in 25% reduction of the within-event standard deviation that reduced the total standard deviation by about 15%.

Design of the next generation target at Lujan center, LANSCE.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ferres, Laurent

2016-07-27

This is a presentation given at Los Alamos National Laboratory (LANL) on the design of the next generation target at Lujan center, LANSCE. The motivation for this design is to enable new nuclear physics experiments (defense program applications (DANCE)) that are currently limited by neutron intensity or energy resolution available at LANSCE. The target is being redesigned so that the Flight Paths in the upper tier provide a higher intensity in the epithermal and medium energy ranges.

View of camera station located northeast of Building 70022, facing ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View of camera station located northeast of Building 70022, facing northwest - Naval Ordnance Test Station Inyokern, Randsburg Wash Facility Target Test Towers, Tower Road, China Lake, Kern County, CA

A Simple Space Station Rescue Vehicle

NASA Technical Reports Server (NTRS)

Petro, Andrew

1995-01-01

Early in the development of the Space Station it was determined that there is a need to have a vehicle which could be used in the event that the Space Station crew need to quickly depart and return to Earth when the Space Shuttle is not available. Unplanned return missions might occur because of a medical emergency, a major Space Station failure, or if there is a long-term interruption in the delivery of logistics to the Station. The rescue vehicle ms envisioned as a simple capsule-type spacecraft which would be maintained in a dormant state at the Station for several years and be quickly activated by the crew when needed. During the assembly phase for the International Space Station, unplanned return missions will be performed by the Russian Soyuz vehicle, which can return up to three people. When the Station assembly is complete there will be a need for rescue capability for up to six people. This need might be met by an additional Soyuz vehicle or by a new vehicle which might come from a variety of sources. This paper describes one candidate concept for a Space Station rescue vehicle. The proposed rescue vehicle design has the blunt-cone shape of the Apollo command module but with a larger diameter. The rescue vehicle would be delivered to the Station in the payload bay of the Space Shuttle. The spacecraft design can accommodate six to eight people for a one-day return mission. All of the systems for the mission including deorbit propulsion are contained within the conical spacecraft and so there is no separate service module. The use of the proven Apollo re-entry shape would greatly reduce the time and cost for development and testing. Other aspects of the design are also intended to minimize development cost and simplify operations. This paper will summarize the evolution of rescue vehicle concepts, the functional requirements for a rescue vehicle, and describe the proposed design.

RobOKoD: microbial strain design for (over)production of target compounds.

PubMed

Stanford, Natalie J; Millard, Pierre; Swainston, Neil

2015-01-01

Sustainable production of target compounds such as biofuels and high-value chemicals for pharmaceutical, agrochemical, and chemical industries is becoming an increasing priority given their current dependency upon diminishing petrochemical resources. Designing these strains is difficult, with current methods focusing primarily on knocking-out genes, dismissing other vital steps of strain design including the overexpression and dampening of genes. The design predictions from current methods also do not translate well-into successful strains in the laboratory. Here, we introduce RobOKoD (Robust, Overexpression, Knockout and Dampening), a method for predicting strain designs for overproduction of targets. The method uses flux variability analysis to profile each reaction within the system under differing production percentages of target-compound and biomass. Using these profiles, reactions are identified as potential knockout, overexpression, or dampening targets. The identified reactions are ranked according to their suitability, providing flexibility in strain design for users. The software was tested by designing a butanol-producing Escherichia coli strain, and was compared against the popular OptKnock and RobustKnock methods. RobOKoD shows favorable design predictions, when predictions from these methods are compared to a successful butanol-producing experimentally-validated strain. Overall RobOKoD provides users with rankings of predicted beneficial genetic interventions with which to support optimized strain design.

Tunnel and Station Cost Methodology Volume II: Stations

DOT National Transportation Integrated Search

1981-01-01

The main objective of this study was to develop a model for estimating the cost of subway station and tunnel construction. This report describes a cost estimating methodology for subway tunnels that can be used by planners, designers, owners, and gov...

A target design for irradiation of NaI at high beam current.

NASA Technical Reports Server (NTRS)

Blue, J. W.; Sodd, V. J.

1972-01-01

A solution to the targetry problems encountered when the iodine nucleus is a target for cyclotron irradiation is given as a new target design. A target based on this design has been used in 30 microampere irradiations of 46 MeV alpha particles for one-half hour without significant damage. Such an irradiation produces 6 to 7 mCi of Cs-129, an isotope useful in nuclear medicine. This target should also be considered for cyclotron production of the radioisotopes Cs-127, I-123, and Xe-127.

High-efficiency-release targets for use at ISOL facilities: computational design

NASA Astrophysics Data System (ADS)

Liu, Y.; Alton, G. D.

1999-12-01

This report describes efforts made at the Oak Ridge National Laboratory to design high-efficiency-release targets that simultaneously incorporate the short diffusion lengths, high permeabilities, controllable temperatures, and heat-removal properties required for the generation of useful radioactive ion beam (RIB) intensities for nuclear physics and astrophysics research using the isotope separation on-line (ISOL) technique. Short diffusion lengths are achieved either by using thin fibrous target materials or by coating thin layers of selected target material onto low-density carbon fibers such as reticulated-vitreous-carbon fiber (RVCF) or carbon-bonded-carbon fiber (CBCF) to form highly permeable composite target matrices. Computational studies that simulate the generation and removal of primary beam deposited heat from target materials have been conducted to optimize the design of target/heat-sink systems for generating RIBs. The results derived from diffusion release-rate simulation studies for selected targets and thermal analyses of temperature distributions within a prototype target/heat-sink system subjected to primary ion beam irradiation are presented in this report.

Mars rover/sample return mission requirements affecting space station

NASA Technical Reports Server (NTRS)

1988-01-01

The possible interfaces between the Space Station and the Mars Rover/Sample Return (MRSR) mission are defined. In order to constrain the scope of the report a series of seven design reference missions divided into three major types were assumed. These missions were defined to span the probable range of Space Station-MRSR interactions. The options were reduced, the MRSR sample handling requirements and baseline assumptions about the MRSR hardware and the key design features and requirements of the Space Station are summarized. Only the aspects of the design reference missions necessary to define the interfaces, hooks and scars, and other provisions on the Space Station are considered. An analysis of each of the three major design reference missions, is reported, presenting conceptual designs of key hardware to be mounted on the Space Station, a definition of weights, interfaces, and required hooks and scars.

Space Station accommodation of attached payloads

NASA Technical Reports Server (NTRS)

Browning, Ronald K.; Gervin, Janette C.

1987-01-01

The Attached Payload Accommodation Equipment (APAE), which provides the structure to attach payloads to the Space Station truss assembly, to access Space Station resources, and to orient payloads relative to specified targets, is described. The main subelements of the APAE include a station interface adapter, payload interface adapter, subsystem support module, contamination monitoring system, payload pointing system, and attitude determination system. These components can be combined to provide accommodations for small single payloads, small multiple payloads, large self-supported payloads, carrier-mounted payloads, and articulated payloads. The discussion also covers the power, thermal, and data/communications subsystems and operations.

Design and Fabrication of a Differential Electrostatic Accelerometer for Space-Station Testing of the Equivalence Principle.

PubMed

Han, Fengtian; Liu, Tianyi; Li, Linlin; Wu, Qiuping

2016-08-10

The differential electrostatic space accelerometer is an equivalence principle (EP) experiment instrument proposed to operate onboard China's space station in the 2020s. It is designed to compare the spin-spin interaction between two rotating extended bodies and the Earth to a precision of 10(-12), which is five orders of magnitude better than terrestrial experiment results to date. To achieve the targeted test accuracy, the sensitive space accelerometer will use the very soft space environment provided by a quasi-drag-free floating capsule and long-time observation of the free-fall mass motion for integration of the measurements over 20 orbits. In this work, we describe the design and capability of the differential accelerometer to test weak space acceleration. Modeling and simulation results of the electrostatic suspension and electrostatic motor are presented based on attainable space microgravity condition. Noise evaluation shows that the electrostatic actuation and residual non-gravitational acceleration are two major noise sources. The evaluated differential acceleration noise is 1.01 × 10(-9) m/s²/Hz(1/2) at the NEP signal frequency of 0.182 mHz, by neglecting small acceleration disturbances. The preliminary work on development of the first instrument prototype is introduced for on-ground technological assessments. This development has already confirmed several crucial fabrication processes and measurement techniques and it will open the way to the construction of the final differential space accelerometer.

Design and Fabrication of a Differential Electrostatic Accelerometer for Space-Station Testing of the Equivalence Principle

PubMed Central

Han, Fengtian; Liu, Tianyi; Li, Linlin; Wu, Qiuping

2016-01-01

The differential electrostatic space accelerometer is an equivalence principle (EP) experiment instrument proposed to operate onboard China’s space station in the 2020s. It is designed to compare the spin-spin interaction between two rotating extended bodies and the Earth to a precision of 10−12, which is five orders of magnitude better than terrestrial experiment results to date. To achieve the targeted test accuracy, the sensitive space accelerometer will use the very soft space environment provided by a quasi-drag-free floating capsule and long-time observation of the free-fall mass motion for integration of the measurements over 20 orbits. In this work, we describe the design and capability of the differential accelerometer to test weak space acceleration. Modeling and simulation results of the electrostatic suspension and electrostatic motor are presented based on attainable space microgravity condition. Noise evaluation shows that the electrostatic actuation and residual non-gravitational acceleration are two major noise sources. The evaluated differential acceleration noise is 1.01 × 10−9 m/s2/Hz1/2 at the NEP signal frequency of 0.182 mHz, by neglecting small acceleration disturbances. The preliminary work on development of the first instrument prototype is introduced for on-ground technological assessments. This development has already confirmed several crucial fabrication processes and measurement techniques and it will open the way to the construction of the final differential space accelerometer. PMID:27517927

Targeting legume loci: A comparison of three methods for target enrichment bait design in Leguminosae phylogenomics.

PubMed

Vatanparast, Mohammad; Powell, Adrian; Doyle, Jeff J; Egan, Ashley N

2018-03-01

The development of pipelines for locus discovery has spurred the use of target enrichment for plant phylogenomics. However, few studies have compared pipelines from locus discovery and bait design, through validation, to tree inference. We compared three methods within Leguminosae (Fabaceae) and present a workflow for future efforts. Using 30 transcriptomes, we compared Hyb-Seq, MarkerMiner, and the Yang and Smith (Y&S) pipelines for locus discovery, validated 7501 baits targeting 507 loci across 25 genera via Illumina sequencing, and inferred gene and species trees via concatenation- and coalescent-based methods. Hyb-Seq discovered loci with the longest mean length. MarkerMiner discovered the most conserved loci with the least flagged as paralogous. Y&S offered the most parsimony-informative sites and putative orthologs. Target recovery averaged 93% across taxa. We optimized our targeted locus set based on a workflow designed to minimize paralog/ortholog conflation and thus present 423 loci for legume phylogenomics. Methods differed across criteria important for phylogenetic marker development. We recommend Hyb-Seq as a method that may be useful for most phylogenomic projects. Our targeted locus set is a resource for future, community-driven efforts to reconstruct the legume tree of life.

Methods to enable the design of bioactive small molecules targeting RNA.

PubMed

Disney, Matthew D; Yildirim, Ilyas; Childs-Disney, Jessica L

2014-02-21

RNA is an immensely important target for small molecule therapeutics or chemical probes of function. However, methods that identify, annotate, and optimize RNA-small molecule interactions that could enable the design of compounds that modulate RNA function are in their infancies. This review describes recent approaches that have been developed to understand and optimize RNA motif-small molecule interactions, including structure-activity relationships through sequencing (StARTS), quantitative structure-activity relationships (QSAR), chemical similarity searching, structure-based design and docking, and molecular dynamics (MD) simulations. Case studies described include the design of small molecules targeting RNA expansions, the bacterial A-site, viral RNAs, and telomerase RNA. These approaches can be combined to afford a synergistic method to exploit the myriad of RNA targets in the transcriptome.

Test Information Targeting Strategies for Adaptive Multistage Testing Designs.

ERIC Educational Resources Information Center

Luecht, Richard M.; Burgin, William

Adaptive multistage testlet (MST) designs appear to be gaining popularity for many large-scale computer-based testing programs. These adaptive MST designs use a modularized configuration of preconstructed testlets and embedded score-routing schemes to prepackage different forms of an adaptive test. The conditional information targeting (CIT)…

Translating Genetic Research into Preventive Intervention: The Baseline Target Moderated Mediator Design.

PubMed

Howe, George W; Beach, Steven R H; Brody, Gene H; Wyman, Peter A

2015-01-01

In this paper we present and discuss a novel research approach, the baseline target moderated mediation (BTMM) design, that holds substantial promise for advancing our understanding of how genetic research can inform prevention research. We first discuss how genetically informed research on developmental psychopathology can be used to identify potential intervention targets. We then describe the BTMM design, which employs moderated mediation within a longitudinal study to test whether baseline levels of intervention targets moderate the impact of the intervention on change in that target, and whether change in those targets mediates causal impact of preventive or treatment interventions on distal health outcomes. We next discuss how genetically informed BTMM designs can be applied to both microtrials and full-scale prevention trials. We use simulated data to illustrate a BTMM, and end with a discussion of some of the advantages and limitations of this approach.

Translating Genetic Research into Preventive Intervention: The Baseline Target Moderated Mediator Design

PubMed Central

Howe, George W.; Beach, Steven R. H.; Brody, Gene H.; Wyman, Peter A.

2016-01-01

In this paper we present and discuss a novel research approach, the baseline target moderated mediation (BTMM) design, that holds substantial promise for advancing our understanding of how genetic research can inform prevention research. We first discuss how genetically informed research on developmental psychopathology can be used to identify potential intervention targets. We then describe the BTMM design, which employs moderated mediation within a longitudinal study to test whether baseline levels of intervention targets moderate the impact of the intervention on change in that target, and whether change in those targets mediates causal impact of preventive or treatment interventions on distal health outcomes. We next discuss how genetically informed BTMM designs can be applied to both microtrials and full-scale prevention trials. We use simulated data to illustrate a BTMM, and end with a discussion of some of the advantages and limitations of this approach. PMID:26779062

Energy storage and thermal control system design status. [for space station power supplies

NASA Technical Reports Server (NTRS)

Simons, Stephen N.; Willhoite, Bryan C.; Van Ommering, Gert

1989-01-01

The Space Station Freedom electric power system (EPS) will initially rely on photovoltaics for power generation and Ni/H2 batteries for electrical energy storage. The current design for the development status of two major subsystems in the PV Power Module is discussed. The energy storage subsystem comprised of high capacity Ni/H2 batteries and the single-phase thermal control system that rejects the excess heat generated by the batteries and other components associated with power generation andstorage is described.

Designing oral vaccines targeting intestinal dendritic cells.

PubMed

Devriendt, Bert; De Geest, Bruno G; Cox, Eric

2011-04-01

Most pathogens colonize and invade the host at mucosal surfaces, such as the lung and the intestine. To combat intestinal pathogens the induction of local adaptive immune responses is required, which is mainly achieved through oral vaccination. However, most vaccines are ineffective when given orally owing to the hostile environment in the gastrointestinal tract. The encapsulation of antigens in biodegradable microparticulate delivery systems enhances their immunogenicity; however, the uptake of these delivery systems by intestinal immune cells is rather poor. Surface decoration of the particulates with targeting ligands could increase the uptake and mediate the selective targeting of the vaccine to intestinal antigen-presenting cells, including dendritic cells. In this review, current knowledge on dendritic cell subsets is discussed, along with progress in the development of selective antigen targeting to these cells, in addition to focusing on data obtained in mice and, where possible, the pig, as a non-rodent animal model for humans. Moreover, the potential use and benefits of Fcγ receptor-mediated targeting of antigen delivery systems are highlighted. In conclusion, dendritic cell targeting ligands grafted on antigen carrier systems should preferably bind to a conserved endocytotic receptor, facilitating the design of a multispecies vaccine platform, which could elicit robust protective immune responses against enteric pathogens.

A design for an intelligent monitor and controller for space station electrical power using parallel distributed problem solving

NASA Technical Reports Server (NTRS)

Morris, Robert A.

1990-01-01

The emphasis is on defining a set of communicating processes for intelligent spacecraft secondary power distribution and control. The computer hardware and software implementation platform for this work is that of the ADEPTS project at the Johnson Space Center (JSC). The electrical power system design which was used as the basis for this research is that of Space Station Freedom, although the functionality of the processes defined here generalize to any permanent manned space power control application. First, the Space Station Electrical Power Subsystem (EPS) hardware to be monitored is described, followed by a set of scenarios describing typical monitor and control activity. Then, the parallel distributed problem solving approach to knowledge engineering is introduced. There follows a two-step presentation of the intelligent software design for secondary power control. The first step decomposes the problem of monitoring and control into three primary functions. Each of the primary functions is described in detail. Suggestions for refinements and embelishments in design specifications are given.

Astronaut Carl Meade mans pilots station during trajectory control exercise

NASA Image and Video Library

1994-09-12

STS064-22-024 (9-20 Sept. 1994) --- With a manual and lap top computer in front of him, astronaut Carl J. Meade, STS-64 mission specialist, supports operations with the Trajectory Control Sensor (TCS) aboard the Earth-orbiting space shuttle Discovery. For this exercise, Meade temporarily mans the pilot's station on the forward flight deck. The TCS is the work of a team of workers at NASA's Johnson Space Center. Data gathered during this flight was expected to prove valuable in designing and developing a sensor for use during the rendezvous and mating phases of orbiter missions to the space station. For this demonstration, the Shuttle Pointed Autonomous Research Tool for Astronomy 201 (SPARTAN 201) was used as the target vehicle during release and retrieval operations. Photo credit: NASA or National Aeronautics and Space Administration

Dead-blow hammer design applied to a calibration target mechanism to dampen excessive rebound

NASA Technical Reports Server (NTRS)

Lim, Brian Y.

1991-01-01

An existing rotary electromagnetic driver was specified to be used to deploy and restow a blackbody calibration target inside of a spacecraft infrared science instrument. However, this target was much more massive than any other previously inherited design applications. The target experienced unacceptable bounce when reaching its stops. Without any design modification, the momentum generated by the driver caused the target to bounce back to its starting position. Initially, elastomeric dampers were used between the driver and the target. However, this design could not prevent the bounce, and it compromised the positional accuracy of the calibration target. A design that successfully met all the requirements incorporated a sealed pocket 85 percent full of 0.75 mm diameter stainless steel balls in the back of the target to provide the effect of a dead-blow hammer. The energy dissipation resulting from the collision of balls in the pocket successfully dampened the excess momentum generated during the target deployment. The disastrous effects of new requirements on a design with a successful flight history, the modifications that were necessary to make the device work, and the tests performed to verify its functionality are described.

Automating Stowage Operations for the International Space Station

NASA Technical Reports Server (NTRS)

Knight, Russell; Rabideau, Gregg; Mishkin, Andrew; Lee, Young

2013-01-01

A challenge for any proposed mission is to demonstrate convincingly that the proposed systems will in fact deliver the science promised. Funding agencies and mission design personnel are becoming ever more skeptical of the abstractions that form the basis of the current state of the practice with respect to approximating science return. To address this, we have been using automated planning and scheduling technology to provide actual coverage campaigns that provide better predictive performance with respect to science return for a given mission design and set of mission objectives given implementation uncertainties. Specifically, we have applied an adaptation of ASPEN and SPICE to the Eagle-Eye domain that demonstrates the performance of the mission design with respect to coverage of science imaging targets that address climate change and disaster response. Eagle-Eye is an Earth-imaging telescope that has been proposed to fly aboard the International Space Station (ISS).

RobOKoD: microbial strain design for (over)production of target compounds

PubMed Central

Stanford, Natalie J.; Millard, Pierre; Swainston, Neil

2015-01-01

Sustainable production of target compounds such as biofuels and high-value chemicals for pharmaceutical, agrochemical, and chemical industries is becoming an increasing priority given their current dependency upon diminishing petrochemical resources. Designing these strains is difficult, with current methods focusing primarily on knocking-out genes, dismissing other vital steps of strain design including the overexpression and dampening of genes. The design predictions from current methods also do not translate well-into successful strains in the laboratory. Here, we introduce RobOKoD (Robust, Overexpression, Knockout and Dampening), a method for predicting strain designs for overproduction of targets. The method uses flux variability analysis to profile each reaction within the system under differing production percentages of target-compound and biomass. Using these profiles, reactions are identified as potential knockout, overexpression, or dampening targets. The identified reactions are ranked according to their suitability, providing flexibility in strain design for users. The software was tested by designing a butanol-producing Escherichia coli strain, and was compared against the popular OptKnock and RobustKnock methods. RobOKoD shows favorable design predictions, when predictions from these methods are compared to a successful butanol-producing experimentally-validated strain. Overall RobOKoD provides users with rankings of predicted beneficial genetic interventions with which to support optimized strain design. PMID:25853130

Function, form, and technology - The evolution of Space Station in NASA

NASA Technical Reports Server (NTRS)

Fries, S. D.

1985-01-01

The history of major Space Station designs over the last twenty-five years is reviewed. The evolution of design concepts is analyzed with respect to the changing functions of Space Stations; and available or anticipated technology capabilities. Emphasis is given to the current NASA Space Station reference configuration, the 'power tower'. Detailed schematic drawings of the different Space Station designs are provided.

Space station interior noise analysis program

NASA Technical Reports Server (NTRS)

Stusnick, E.; Burn, M.

1987-01-01

Documentation is provided for a microcomputer program which was developed to evaluate the effect of the vibroacoustic environment on speech communication inside a space station. The program, entitled Space Station Interior Noise Analysis Program (SSINAP), combines a Statistical Energy Analysis (SEA) prediction of sound and vibration levels within the space station with a speech intelligibility model based on the Modulation Transfer Function and the Speech Transmission Index (MTF/STI). The SEA model provides an effective analysis tool for predicting the acoustic environment based on proposed space station design. The MTF/STI model provides a method for evaluating speech communication in the relatively reverberant and potentially noisy environments that are likely to occur in space stations. The combinations of these two models provides a powerful analysis tool for optimizing the acoustic design of space stations from the point of view of speech communications. The mathematical algorithms used in SSINAP are presented to implement the SEA and MTF/STI models. An appendix provides an explanation of the operation of the program along with details of the program structure and code.

Infrared fiber-optic fire sensors - Concepts and designs for Space Station applications

NASA Technical Reports Server (NTRS)

Tapphorn, Ralph M.; Porter, Alan R.

1990-01-01

Various design configurations used for testing IR fiber-optic (IFO) fire-sensor concepts are presented. Responsibility measurements conducted to select the best concept are reviewed. The results indicate that IFO fire-sensor systems based on distributed fiber sensors are feasible for future aerospace applications. For Space Station Freedom, these systems offer alternative fire detectors for monitoring areas within equipment or stage compartments where the ventilation may be inadequate for proper operation of smoke detectors. They also allow a large number of areas to be monitored by a single central detector unit, which reduces the associated cost and weight.

Nickel-hydrogen batteries from Intelsat 5 to space station

NASA Technical Reports Server (NTRS)

Vanommering, G.; Applewhite, A. Z.

1986-01-01

The heritage of the Ni-H2 technology that makes the space station application feasible is discussed. It also describes a design for a potential space station Ni-H2 battery system. Specific design values presented here were developed by Ford Aerospace as part of the Rocketdyne team effort on the Phase B Definition and Preliminary Design of the Space Station Power System in support of NASA Lewis Research Center.

Environmental control/life support system for Space Station

NASA Technical Reports Server (NTRS)

Miller, C. W.; Heppner, D. B.; Schubert, F. H.; Dahlhausen, M. J.

1986-01-01

The functional, operational, and design load requirements for the Environmental Control/Life Support System (ECLSS) are described. The ECLSS is divided into two groups: (1) an atmosphere management group and (2) a water and waste management group. The interaction between the ECLSS and the Space Station Habitability System is examined. The cruciform baseline station design, the delta and big T module configuration, and the reference Space Station configuration are evaluated in terms of ECLSS requirements. The distribution of ECLSS equipment in a reference Space Station configuration is studied as a function of initial operating conditions and growth orbit capabilities. The benefits of water electrolysis as a Space Station utility are considered.

DESIGNING AN OPPORTUNITY FUEL WITH BIOMASS AND TIRE-DERIVED FUEL FOR COFIRING AT WILLOW ISLAND GENERATING STATION AND COFIRING SAWDUST WITH COAL AT ALBRIGHT GENERATING STATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

K. Payette; D. Tillman

During the period October 1, 2001--December 31, 2001, Allegheny Energy Supply Co., LLC (Allegheny) completed construction of the Willow Island cofiring project. This included completion of the explosion proof electrical wiring, the control system, and the control software. Procedures for system checkout, shakedown, and initial operation were initiated during this period. During this time period the 100-hour test of the Albright Generating Station cofiring facility was completed. The testing demonstrated that cofiring at the Albright Generating Station could reliably contribute to a ''4P Strategy''--reduction of SO{sub 2}, NO{sub x}, mercury, and greenhouse gas emissions over a significant load range. Duringmore » this period of time Allegheny Energy conducted facility tours of both Albright and Willow Island for the Biomass Interest Group of the Electric Power Research Institute. This report summarizes the activities associated with the Designer Opportunity Fuel program, and demonstrations at Willow Island and Albright Generating Stations. It details the completion of construction activities at the Willow Island site along with the 100-hr test at the Albright site.« less

Methods to enable the design of bioactive small molecules targeting RNA

PubMed Central

Disney, Matthew D.; Yildirim, Ilyas; Childs-Disney, Jessica L.

2014-01-01

RNA is an immensely important target for small molecule therapeutics or chemical probes of function. However, methods that identify, annotate, and optimize RNA-small molecule interactions that could enable the design of compounds that modulate RNA function are in their infancies. This review describes recent approaches that have been developed to understand and optimize RNA motif-small molecule interactions, including Structure-Activity Relationships Through Sequencing (StARTS), quantitative structure-activity relationships (QSAR), chemical similarity searching, structure-based design and docking, and molecular dynamics (MD) simulations. Case studies described include the design of small molecules targeting RNA expansions, the bacterial A-site, viral RNAs, and telomerase RNA. These approaches can be combined to afford a synergistic method to exploit the myriad of RNA targets in the transcriptome. PMID:24357181

Space Station crew safety alternatives study. Volume 5: Space Station safety plan

NASA Technical Reports Server (NTRS)

Mead, G. H.; Peercy, R. L., Jr.; Raasch, R. F.

1985-01-01

The Space Station Safety Plan has been prepared as an adjunct to the subject contract final report, suggesting the tasks and implementation procedures to ensure that threats are addressed and resolution strategy options identified and incorporated into the space station program. The safety program's approach is to realize minimum risk exposure without levying undue design and operational constraints. Safety objectives and risk acceptances are discussed.

Injector design for liner-on-target gas-puff experiments

NASA Astrophysics Data System (ADS)

Valenzuela, J. C.; Krasheninnikov, I.; Conti, F.; Wessel, F.; Fadeev, V.; Narkis, J.; Ross, M. P.; Rahman, H. U.; Ruskov, E.; Beg, F. N.

2017-11-01

We present the design of a gas-puff injector for liner-on-target experiments. The injector is composed of an annular high atomic number (e.g., Ar and Kr) gas and an on-axis plasma gun that delivers an ionized deuterium target. The annular supersonic nozzle injector has been studied using Computational Fluid Dynamics (CFD) simulations to produce a highly collimated (M > 5), ˜1 cm radius gas profile that satisfies the theoretical requirement for best performance on ˜1-MA current generators. The CFD simulations allowed us to study output density profiles as a function of the nozzle shape, gas pressure, and gas composition. We have performed line-integrated density measurements using a continuous wave (CW) He-Ne laser to characterize the liner gas density. The measurements agree well with the CFD values. We have used a simple snowplow model to study the plasma sheath acceleration in a coaxial plasma gun to help us properly design the target injector.

Injector design for liner-on-target gas-puff experiments.

PubMed

Valenzuela, J C; Krasheninnikov, I; Conti, F; Wessel, F; Fadeev, V; Narkis, J; Ross, M P; Rahman, H U; Ruskov, E; Beg, F N

2017-11-01

We present the design of a gas-puff injector for liner-on-target experiments. The injector is composed of an annular high atomic number (e.g., Ar and Kr) gas and an on-axis plasma gun that delivers an ionized deuterium target. The annular supersonic nozzle injector has been studied using Computational Fluid Dynamics (CFD) simulations to produce a highly collimated (M > 5), ∼1 cm radius gas profile that satisfies the theoretical requirement for best performance on ∼1-MA current generators. The CFD simulations allowed us to study output density profiles as a function of the nozzle shape, gas pressure, and gas composition. We have performed line-integrated density measurements using a continuous wave (CW) He-Ne laser to characterize the liner gas density. The measurements agree well with the CFD values. We have used a simple snowplow model to study the plasma sheath acceleration in a coaxial plasma gun to help us properly design the target injector.

Space Station tethered elevator system

NASA Technical Reports Server (NTRS)

Haddock, Michael H.; Anderson, Loren A.; Hosterman, K.; Decresie, E.; Miranda, P.; Hamilton, R.

1989-01-01

The optimized conceptual engineering design of a space station tethered elevator is presented. The tethered elevator is an unmanned, mobile structure which operates on a ten-kilometer tether spanning the distance between Space Station Freedom and a platform. Its capabilities include providing access to residual gravity levels, remote servicing, and transportation to any point along a tether. The report discusses the potential uses, parameters, and evolution of the spacecraft design. Emphasis is placed on the elevator's structural configuration and three major subsystem designs. First, the design of elevator robotics used to aid in elevator operations and tethered experimentation is presented. Second, the design of drive mechanisms used to propel the vehicle is discussed. Third, the design of an onboard self-sufficient power generation and transmission system is addressed.

Adaptive waveform optimization design for target detection in cognitive radar

NASA Astrophysics Data System (ADS)

Zhang, Xiaowen; Wang, Kaizhi; Liu, Xingzhao

2017-01-01

The problem of adaptive waveform design for target detection in cognitive radar (CR) is investigated. This problem is analyzed in signal-dependent interference, as well as additive channel noise for extended target with unknown target impulse response (TIR). In order to estimate the TIR accurately, the Kalman filter is used in target tracking. In each Kalman filtering iteration, a flexible online waveform spectrum optimization design taking both detection and range resolution into account is modeled in Fourier domain. Unlike existing CR waveform, the proposed waveform can be simultaneously updated according to the environment information fed back by receiver and radar performance demands. Moreover, the influence of waveform spectral phase to radar performance is analyzed. Simulation results demonstrate that CR with the proposed waveform performs better than a traditional radar system with a fixed waveform and offers more flexibility and suitability. In addition, waveform spectral phase will not influence tracking, detection, and range resolution performance but will greatly influence waveform forming speed and peak-to-average power ratio.

Conceptual design considerations and neutronics of lithium fall laser fusion target chambers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meier, W.R.; Thomson, W.B.

1978-05-31

Atomics International and Lawrence Livermore Laboratory are involved in the conceptual design of a laser fusion power plant incorporating the lithium fall target chamber. In this paper we discuss some of the more important design considerations for the target chamber and evaluate its nuclear performance. Sizing and configuration of the fall, hydraulic effects, and mechanical design considerations are addressed. The nuclear aspects examined include tritium breeding, energy deposition, and radiation damage.

Space Station Facility government estimating

NASA Technical Reports Server (NTRS)

Brown, Joseph A.

1993-01-01

This new, unique Cost Engineering Report introduces the 800-page, C-100 government estimate for the Space Station Processing Facility (SSPF) and Volume IV Aerospace Construction Price Book. At the January 23, 1991, bid opening for the SSPF, the government cost estimate was right on target. Metric, Inc., Prime Contractor, low bid was 1.2 percent below the government estimate. This project contains many different and complex systems. Volume IV is a summary of the cost associated with construction, activation and Ground Support Equipment (GSE) design, estimating, fabrication, installation, testing, termination, and verification of this project. Included are 13 reasons the government estimate was so accurate; abstract of bids, for 8 bidders and government estimate with additive alternates, special labor and materials, budget comparison and system summaries; and comments on the energy credit from local electrical utility. This report adds another project to our continuing study of 'How Does the Low Bidder Get Low and Make Money?' which was started in 1967, and first published in the 1973 AACE Transaction with 18 ways the low bidders get low. The accuracy of this estimate proves the benefits of our Kennedy Space Center (KSC) teamwork efforts and KSC Cost Engineer Tools which are contributing toward our goals of the Space Station.

Advances in target design for heavy ion fusion

NASA Astrophysics Data System (ADS)

Callahan, D. A.; Tabak, M.; Bennett, G. R.; Cuneo, M. E.; Vesey, R. A.; Nikroo, A.; Czechowicz, D.; Steinman, D.

2005-12-01

Over the past few years, the emphasis in heavy ion target design has moved from the distributed radiator target to the 'hybrid' target because the hybrid target allows a larger beam focal spot than the distributed radiator (~5 mm radius rather than ~2 mm radius). The larger spot relaxes some of the requirements on the driver, but introduces some new target physics issues. Most notable is the use of shine shields and shims in the hohlraum to achieve symmetry rather than achieving symmetry by beam placement. The shim is a thin layer of material placed on or near the capsule surface to block a small amount of excess radiation. While we have been developing this technique for the heavy ion hybrid target, the technique can also be used in any indirect drive target. We have begun testing the concept of a shim to improve symmetry using a double-ended z-pinch hohlraum on the Sandia Z-machine. Experiments using shimmed thin wall capsules have shown that we can reverse the sign of a P2 asymmetry and significantly reduce the size of a P4 asymmetry. These initial experiments demonstrate the concept of a shim as another method for controlling early time asymmetries in ICF capsules.

Designing an Active Target Test Projection Chamber

NASA Astrophysics Data System (ADS)

Koci, James; Tan Ahn Collaboration, Dr.; Nicolas Dixneuf Collaboration

2015-10-01

The development of instrumentation in nuclear physics is crucial for advancing our ability to measure the properties of exotic nuclei. One limitation of the use of exotic nuclei in experiment is their very low production intensities. Recently, detectors, called active-target dectectors, have been developed to address this issue. Active-target detectors use a gas medium to image charged-particle tracks that are emitted in nuclear reactions. Last semester, I designed a vacuum chamber to be used in developing Micro-Pattern Gas detectors that will upgrade the capabilities of an active-target detector called the Prototype AT-TPC. With the exterior of the chamber complete, I have now been using an electric field modeling program, Garfield, developed by CERN to design a field cage to be placed within the vacuum chamber. The field cage will be a box-like apparatus consisting of two parallel metal plates connected with a resistor chain and attached to wires wrapped between them. The cage will provide a uniform electric field within the chamber to drift electrons from nuclear reactions down to the detector in the bottom of the chamber. These signals are then amplified by a proportional counter, and the data is sent to a computer. For the long term, we would like to incorporate a Micro-Pattern Gas Detectors in the interior of the chamber and eventually use the AT-TPC to examine various nuclei. Dr. Ahn is my advising professor.

Space station structures development

NASA Technical Reports Server (NTRS)

Teller, V. B.

1986-01-01

A study of three interrelated tasks focusing on deployable Space Station truss structures is discussed. Task 1, the development of an alternate deployment system for linear truss, resulted in the preliminary design of an in-space reloadable linear motor deployer. Task 2, advanced composites deployable truss development, resulted in the testing and evaluation of composite materials for struts used in a deployable linear truss. Task 3, assembly of structures in space/erectable structures, resulted in the preliminary design of Space Station pressurized module support structures. An independent, redundant support system was developed for the common United States modules.

Challenges of Sustaining the International Space Station through 2020 and Beyond: Including Epistemic Uncertainty in Reassessing Confidence Targets

NASA Technical Reports Server (NTRS)

Anderson, Leif; Carter-Journet, Katrina; Box, Neil; DiFilippo, Denise; Harrington, Sean; Jackson, David; Lutomski, Michael

2012-01-01

This paper introduces an analytical approach, Probability and Confidence Trade-space (PACT), which can be used to assess uncertainty in International Space Station (ISS) hardware sparing necessary to extend the life of the vehicle. There are several key areas under consideration in this research. We investigate what sparing confidence targets may be reasonable to ensure vehicle survivability and for completion of science on the ISS. The results of the analysis will provide a methodological basis for reassessing vehicle subsystem confidence targets. An ongoing annual analysis currently compares the probability of existing spares exceeding the total expected unit demand of the Orbital Replacement Unit (ORU) in functional hierarchies approximating the vehicle subsystems. In cases where the functional hierarchies availability does not meet subsystem confidence targets, the current sparing analysis further identifies which ORUs may require additional spares to extend the life of the ISS. The resulting probability is dependent upon hardware reliability estimates. However, the ISS hardware fleet carries considerable epistemic uncertainty (uncertainty in the knowledge of the true hardware failure rate), which does not currently factor into the annual sparing analysis. The existing confidence targets may be conservative. This paper will also discuss how confidence targets may be relaxed based on the inclusion of epistemic uncertainty for each ORU. The paper will conclude with strengths and limitations for implementing the analytical approach in sustaining the ISS through end of life, 2020 and beyond.

Space Station Cathode Design, Performance, and Operating Specifications

NASA Technical Reports Server (NTRS)

Patterson, Michael J.; Verhey, Timothy R.; Soulas, George; Zakany, James

1998-01-01

A plasma contactor system was baselined for the International Space Station (ISS) to eliminate/mitigate damaging interactions with the space environment. The system represents a dual-use technology which is a direct outgrowth of the NASA electric propulsion program and, in particular, the technology development efforts on ion thruster systems. The plasma contactor includes a hollow cathode assembly (HCA), a power electronics unit, and a xenon gas feed system. Under a pre-flight development program, these subsystems were taken to the level of maturity appropriate for transfer to U.S. industry for final development. NASA's Lewis Research Center was subsequently requested by ISS to manufacture and deliver the engineering model, qualification model, and flight HCA units. To date, multiple units have been built. One cathode has demonstrated approximately 28,000 hours lifetime, two development unit HCAs have demonstrated over 10,000 hours lifetime, and one development unit HCA has demonstrated more than 32,000 ignitions. All 8 flight HCAs have been manufactured, acceptance tested, and are ready for delivery to the flight contractor. This paper discusses the requirements, mechanical design, performance, operating specifications, and schedule for the plasma contactor flight HCAs.

Introduction to spallation physics and spallation-target design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Russell, G.J.; Pitcher, E.J.; Daemen, L.L.

1995-10-01

When coupled with the spallation process in appropriate target materials, high-power accelerators can be used to produce large numbers of neutrons, thus providing an alternate method to the use of nuclear reactors for this purpose. Spallation offers exciting new possibilities for generating intense neutron fluxes for a variety of applications, including: (a) spallation-neutron sources for materials science research; (b) accelerator-based production of tritium; (c) accelerator-based transmutation of waste; (d) accelerator-based destruction of plutonium; and (e) radioisotope production for medical and energy applications. Target design plays a key role in these applications, with neutron production/leakage being strongly dependent on the incidentmore » particle type and energy, and target material and geometry.« less

9 CFR 72.16 - Designated dipping stations to be approved by the Administrator, APHIS on recommendations of...

Code of Federal Regulations, 2010 CFR

2010-01-01

... approved by the Administrator, APHIS on recommendations of State authorities; facilities. 72.16 Section 72... CATTLE § 72.16 Designated dipping stations to be approved by the Administrator, APHIS on recommendations of State authorities; facilities. When deemed advisable and upon recommendation by the proper...

Effects of design on cost of flat-plate solar photovoltaic arrays for terrestrial central station power applications

NASA Technical Reports Server (NTRS)

Tsou, P.; Stolte, W.

1978-01-01

The paper examines the impact of module and array designs on the balance-of-plant costs for flat-plate terrestrial central station power applications. Consideration is given to the following types of arrays: horizontal, tandem, augmented, tilt adjusted, and E-W tracking. The life-cycle cost of a 20-year plant life serves as the costing criteria for making design and cost tradeoffs. A tailored code of accounts is developed for determining consistent photovoltaic power plant costs and providing credible photovoltaic system cost baselines for flat-plate module and array designs by costing several varying array design approaches.

Subway platform air quality: Assessing the influences of tunnel ventilation, train piston effect and station design

NASA Astrophysics Data System (ADS)

Moreno, T.; Pérez, N.; Reche, C.; Martins, V.; de Miguel, E.; Capdevila, M.; Centelles, S.; Minguillón, M. C.; Amato, F.; Alastuey, A.; Querol, X.; Gibbons, W.

2014-08-01

A high resolution air quality monitoring campaign (PM, CO2 and CO) was conducted on differently designed station platforms in the Barcelona subway system under: (a) normal forced tunnel ventilation, and (b) with daytime tunnel ventilation systems shut down. PM concentrations are highly variable (6-128 μgPM1 m-3, 16-314 μgPM3 m-3, and 33-332 μgPM10 m-3, 15-min averages) depending on ventilation conditions and station design. Narrow platforms served by single-track tunnels are heavily dependent on forced tunnel ventilation and cannot rely on the train piston effect alone to reduce platform PM concentrations. In contrast PM levels in stations with spacious double-track tunnels are not greatly affected when tunnel ventilation is switched off, offering the possibility of significant energy savings without damaging air quality. Sampling at different positions along the platform reveals considerable lateral variation, with the greatest accumulation of particulates occurring at one end of the platform. Passenger accesses can dilute PM concentrations by introducing cleaner outside air, although lateral down-platform accesses are less effective than those positioned at the train entry point. CO concentrations on the platform are very low (≤1 ppm) and probably controlled by ingress of traffic-contaminated street-level air. CO2 averages range from 371 to 569 ppm, changing during the build-up and exchange of passengers with each passing train.

Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Strauch, Eva-Maria; Bernard, Steffen M.; La, David

Many viral surface glycoproteins and cell surface receptors are homo-oligomers1, 2, 3, 4, and thus can potentially be targeted by geometrically matched homo-oligomers that engage all subunits simultaneously to attain high avidity and/or lock subunits together. The adaptive immune system cannot generally employ this strategy since the individual antibody binding sites are not arranged with appropriate geometry to simultaneously engage multiple sites in a single target homo-oligomer. We describe a general strategy for the computational design of homo-oligomeric protein assemblies with binding functionality precisely matched to homo-oligomeric target sites5, 6, 7, 8. In the first step, a small protein ismore » designed that binds a single site on the target. In the second step, the designed protein is assembled into a homo-oligomer such that the designed binding sites are aligned with the target sites. We use this approach to design high-avidity trimeric proteins that bind influenza A hemagglutinin (HA) at its conserved receptor binding site. The designed trimers can both capture and detect HA in a paper-based diagnostic format, neutralizes influenza in cell culture, and completely protects mice when given as a single dose 24 h before or after challenge with influenza.« less

A manned-machine space station construction concept

NASA Technical Reports Server (NTRS)

Mikulas, M. M., Jr.; Bush, H. G.; Wallsom, R. E.; Dorsey, J. T.; Rhodes, M. D.

1984-01-01

A design concept for the construction of a permanent manned space station is developed and discussed. The main considerations examined in developing the design concept are: (1) the support structure of the station be stiff enough to preclude the need for an elaborate on-orbit system to control structural response, (2) the station support structure and solar power system be compatible with existing technology, and (3) the station be capable of growing in a systematic modular fashion. The concept is developed around the assembly of truss platforms by pressure-suited astronauts operating in extravehicular activity (EVA), assisted by a machine (Assembly and Transport Vehicle, ATV) to position the astronauts at joint locations where they latch truss members in place. The ATV is a mobile platform that is attached to and moves on the station support structure using pegs attached to each truss joint. The operation of the ATV is described and a number of conceptual configurations for potential space stations are developed.

Workshop on Instructional Features and Instructor/Operator Station Design for Training Systems.

ERIC Educational Resources Information Center

Ricard, G. L., Ed.; And Others

These 19 papers review current research and development work related to the operation of the instructor's station of training systems, with emphasis on developing functional station specifications applicable to a variety of simulation-based training situations. Topics include (1) instructional features; (2) instructor/operator station research and…

Modular space station

NASA Technical Reports Server (NTRS)

1972-01-01

The modular space station comprising small, shuttle-launched modules, and characterized by low initial cost and incremental manning, is described. The initial space station is designed to be delivered into orbit by three space shuttles and assembled in space. The three sections are the power/subsystems module, the crew/operations module, and the general purpose laboratory module. It provides for a crew of six. Subsequently duplicate/crew/operations and power/subsystems modules will be mated to the original modules, and provide for an additional six crewmen. A total of 17 research and applications modules is planned, three of which will be free-flying modules. Details are given on the program plan, modular characteristics, logistics, experiment support capability and requirements, operations analysis, design support analyses, and shuttle interfaces.

Battery charging stations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bergey, M.

1997-12-01

This paper discusses the concept of battery charging stations (BCSs), designed to service rural owners of battery power sources. Many such power sources now are transported to urban areas for recharging. A BCS provides the opportunity to locate these facilities closer to the user, is often powered by renewable sources, or hybrid systems, takes advantage of economies of scale, and has the potential to provide lower cost of service, better service, and better cost recovery than other rural electrification programs. Typical systems discussed can service 200 to 1200 people, and consist of stations powered by photovoltaics, wind/PV, wind/diesel, or dieselmore » only. Examples of installed systems are presented, followed by cost figures, economic analysis, and typical system design and performance numbers.« less

Evolution of the Space Station Robotic Manipulator

NASA Technical Reports Server (NTRS)

Razvi, Shakeel; Burns, Susan H.

2007-01-01

The Space Station Remote Manipulator System (SSRMS), Canadarm2, was launched in 2001 and deployed on the International Space Station (ISS). The Canadarm2 has been instrumental in ISS assembly and maintenance. Canadarm2 shares its heritage with the Space Shuttle Arm (Canadarm). This article explores the evolution from the Shuttle Canadarm to the Space Station Canadarm2 design, which incorporates a 7 degree of freedom design, larger joints, and changeable operating base. This article also addresses phased design, redundancy, life and maintainability requirements. The design of Canadarm2 meets unique ISS requirements, including expanded handling capability and the ability to be maintained on orbit. The size of ISS necessitated a mobile manipulator, resulting in the unique capability of Canadarm2 to relocate by performing a walk off to base points located along the Station, and interchanging the tip and base of the manipulator. This provides the manipulator with reach and access to a large part of the Station, enabling on-orbit assembly of the Station and providing support to Extra-Vehicular Activity (EVA). Canadarm2 is evolving based on on-orbit operational experience and new functionality requirements. SSRMS functionality is being developed in phases to support evolving ISS assembly and operation as modules are added and the Station becomes more complex. Changes to sustaining software, hardware architecture, and operations have significantly enhanced SSRMS capability to support ISS mission requirements. As a result of operational experience, SSRMS changes have been implemented for Degraded Joint Operations, Force Moment Sensor Thermal Protection, Enabling Ground Controlled Operations, and Software Commutation. Planned Canadarm2 design modifications include: Force Moment Accommodation, Smart Safing, Separate Safing, and Hot Backup. In summary, Canadarm2 continues to evolve in support of new ISS requirements and improved operations. It is a tribute to the design that

The Integrated Mission-Planning Station: Functional Requirements, Aviator-Computer Dialogue, and Human Engineering Design Criteria.

DTIC Science & Technology

1983-08-01

AD- R136 99 THE INTEGRATED MISSION-PLNNING STATION: FUNCTIONAL 1/3 REQUIREMENTS AVIATOR-..(U) RNACAPR SCIENCES INC SANTA BARBARA CA S P ROGERS RUG...Continue on reverse side o necess.ar and identify by btock number) Interactive Systems Aviation Control-Display Functional Require- Plan-Computer...Dialogue Avionics Systems ments Map Display Army Aviation Design Criteria Helicopters M4ission Planning Cartography Digital Map Human Factors Navigation

47 CFR 25.271 - Control of transmitting stations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... station. (b) The licensee of a transmitting earth station licensed under this part shall ensure that a trained operator is present on the earth station site, or at a designated remote control point for the earth station, at all times that transmissions are being conducted. No operator's license is required...

47 CFR 25.271 - Control of transmitting stations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... station. (b) The licensee of a transmitting earth station licensed under this part shall ensure that a trained operator is present on the earth station site, or at a designated remote control point for the earth station, at all times that transmissions are being conducted. No operator's license is required...

47 CFR 25.271 - Control of transmitting stations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... station. (b) The licensee of a transmitting earth station licensed under this part shall ensure that a trained operator is present on the earth station site, or at a designated remote control point for the earth station, at all times that transmissions are being conducted. No operator's license is required...

47 CFR 25.271 - Control of transmitting stations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... station. (b) The licensee of a transmitting earth station licensed under this part shall ensure that a trained operator is present on the earth station site, or at a designated remote control point for the earth station, at all times that transmissions are being conducted. No operator's license is required...

47 CFR 25.271 - Control of transmitting stations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... station. (b) The licensee of a transmitting earth station licensed under this part shall ensure that a trained operator is present on the earth station site, or at a designated remote control point for the earth station, at all times that transmissions are being conducted. No operator's license is required...

9 CFR 72.16 - Designated dipping stations to be approved by the Administrator, APHIS on recommendations of...

Code of Federal Regulations, 2014 CFR

2014-01-01

....16 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS BOVINE BABESIOSIS § 72.16... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Designated dipping stations to be...

Space Station Redesign Team: Final report to the Advisory Committee on the Redesign of the Space Station

NASA Technical Reports Server (NTRS)

1993-01-01

This report is the result of the Space Station Redesign Team's activity. Its purpose is to present without bias, and in appropriate detail, the characteristics and cost of three design and management approaches for the Space Station Freedom. It was presented to the Advisory Committee on the Redesign of the Space Station on 7 Jun. 1993, in Washington, D.C.

Design of electric vehicle charging station based on wind and solar complementary power supply

NASA Astrophysics Data System (ADS)

Wang, Li

2018-05-01

Electric vehicles have become a major trend in the development of the automobile industry. Green energy saving is an important feature of their development. At the same time, the related charging facilities construction is also critical. If we improve the charging measures to adapt to its green energy-saving features, it will be to a greater extent to promote its further development. This article will propose a highly efficient green energy-saving charging station designed for the electric vehicles.

Target-cancer cell specific activatable fluorescence imaging Probes: Rational Design and in vivo Applications

PubMed Central

Kobayashi, Hisataka; Choyke, Peter L.

2010-01-01

CONSPECTUS Conventional imaging methods, such as angiography, computed tomography, magnetic resonance imaging and radionuclide imaging, rely on contrast agents (iodine, gadolinium, radioisotopes) that are “always on”. While these agents have proven clinically useful, they are not sufficiently sensitive because of the inadequate target to background ratio. A unique aspect of optical imaging is that fluorescence probes can be designed to be activatable, i.e. only “turned on” under certain conditions. These probes can be designed to emit signal only after binding a target tissue, greatly increasing sensitivity and specificity in the detection of disease. There are two basic types of activatable fluorescence probes; 1) conventional enzymatically activatable probes, which exist in the quenched state until activated by enzymatic cleavage mostly outside of the cells, and 2) newly designed target-cell specific activatable probes, which are quenched until activated in targeted cells by endolysosomal processing that results when the probe binds specific cell-surface receptors and is subsequently internalized. Herein, we present a review of the rational design and in vivo applications of target-cell specific activatable probes. Designing these probes based on their photo-chemical (e.g. activation strategy), pharmacological (e.g. biodistribution), and biological (e.g. target specificity) properties has recently allowed the rational design and synthesis of target-cell specific activatable fluorescence imaging probes, which can be conjugated to a wide variety of targeting molecules. Several different photo-chemical mechanisms have been utilized, each of which offers a unique capability for probe design. These include: self-quenching, homo- and hetero-fluorescence resonance energy transfer (FRET), H-dimer formation and photon-induced electron transfer (PeT). In addition, the repertoire is further expanded by the option for reversibility or irreversibility of the signal

Space Station Furnace Facility. Volume 1: Requirements definition and conceptual design study, executive summary

NASA Technical Reports Server (NTRS)

1992-01-01

The Space Station Freedom Furnace (SSFF) Study was awarded on June 2, 1989, to Teledyne Brown Engineering (TBE) to define an advanced facility for materials research in the microgravity environment of Space Station Freedom (SSF). The SSFF will be designed for research in the solidification of metals and alloys, the crystal growth of electronic and electro-optical materials, and research in glasses and ceramics. The SSFF is one of the first 'facility' class payloads planned by the Microgravity Science and Applications Division (MSAD) of the Office of Space Science and Applications of NASA Headquarters. This facility is planned for early deployment during man-tended operations of the SSF with continuing operations through the Permanently Manned Configuration (PMC). The SSFF will be built around a general 'Core' facility which provides common support functions not provided by SSF, common subsystems which are best centralized, and common subsystems which are best distributed with each experiment module. The intent of the facility approach is to reduce the overall cost associated with implementing and operating a variety of experiments. This is achieved by reducing the launch mass and simplifying the hardware development and qualification processes associated with each experiment. The Core will remain on orbit and will require only periodic maintenance and upgrading while new Furnace Modules, samples, and consumables are developed, qualified, and transported to the SSF. The SSFF Study was divided into two phases: phase 1, a definition study phase, and phase 2, a design and development phase. The definition phase 1 is addressed. Phase 1 was divided into two parts. In the first part, the basic part of the effort, covered the preliminary definition and assessment of requirements; conceptual design of the SSFF; fabrication of mockups; and the preparation for and support of the Conceptual Design Review (CoDR). The second part, the option part, covered requirements update and

Computational design of nanoparticle drug delivery systems for selective targeting

NASA Astrophysics Data System (ADS)

Duncan, Gregg A.; Bevan, Michael A.

2015-09-01

Ligand-functionalized nanoparticles capable of selectively binding to diseased versus healthy cell populations are attractive for improved efficacy of nanoparticle-based drug and gene therapies. However, nanoparticles functionalized with high affinity targeting ligands may lead to undesired off-target binding to healthy cells. In this work, Monte Carlo simulations were used to quantitatively determine net surface interactions, binding valency, and selectivity between targeted nanoparticles and cell surfaces. Dissociation constant, KD, and target membrane protein density, ρR, are explored over a range representative of healthy and cancerous cell surfaces. Our findings show highly selective binding to diseased cell surfaces can be achieved with multiple, weaker affinity targeting ligands that can be further optimized by varying the targeting ligand density, ρL. Using the approach developed in this work, nanomedicines can be optimally designed for exclusively targeting diseased cells and tissues.Ligand-functionalized nanoparticles capable of selectively binding to diseased versus healthy cell populations are attractive for improved efficacy of nanoparticle-based drug and gene therapies. However, nanoparticles functionalized with high affinity targeting ligands may lead to undesired off-target binding to healthy cells. In this work, Monte Carlo simulations were used to quantitatively determine net surface interactions, binding valency, and selectivity between targeted nanoparticles and cell surfaces. Dissociation constant, KD, and target membrane protein density, ρR, are explored over a range representative of healthy and cancerous cell surfaces. Our findings show highly selective binding to diseased cell surfaces can be achieved with multiple, weaker affinity targeting ligands that can be further optimized by varying the targeting ligand density, ρL. Using the approach developed in this work, nanomedicines can be optimally designed for exclusively targeting

Ergonomic implementation and work station design for quilt manufacturing unit.

PubMed

Vinay, Deepa; Kwatra, Seema; Sharma, Suneeta; Kaur, Nirmal

2012-05-01

average working heart rate values were found to reduced by performing the activity using improved technology followed by energy expenditure (6.99 kj/min), total cardiac cost of work (1037.95 beats), physiological cost of work (103.79 beats) and rate of perceived rate of exertion to the score of 2.6 Results of postural analysis that is change in motion at cervical region reveal that range of motion in case of extension was found beyond the normal range in existing setup where as it reduced to normal range in improved work station. The finding of the study concludes that to ensure safety and to reduce occupational health hazards while performing the activity, an ergonomically designed work station by introduction of improved technology option will be a right choice which also enhances the productivity.

Preliminary Design of a Galactic Cosmic Ray Shielding Materials Testbed for the International Space Station

NASA Technical Reports Server (NTRS)

Gaier, James R.; Berkebile, Stephen; Sechkar, Edward A.; Panko, Scott R.

2012-01-01

The preliminary design of a testbed to evaluate the effectiveness of galactic cosmic ray (GCR) shielding materials, the MISSE Radiation Shielding Testbed (MRSMAT) is presented. The intent is to mount the testbed on the Materials International Space Station Experiment-X (MISSE-X) which is to be mounted on the International Space Station (ISS) in 2016. A key feature is the ability to simultaneously test nine samples, including standards, which are 5.25 cm thick. This thickness will enable most samples to have an areal density greater than 5 g/sq cm. It features a novel and compact GCR telescope which will be able to distinguish which cosmic rays have penetrated which shielding material, and will be able to evaluate the dose transmitted through the shield. The testbed could play a pivotal role in the development and qualification of new cosmic ray shielding technologies.

49 CFR 192.173 - Compressor stations: Ventilation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Design of Pipeline Components § 192.173 Compressor stations: Ventilation. Each compressor station building must be ventilated to ensure...

Computational design of high efficiency release targets for use at ISOL facilities

NASA Astrophysics Data System (ADS)

Liu, Y.; Alton, G. D.; Middleton, J. W.

1999-06-01

This report describes efforts made at the Oak Ridge National Laboratory to design high-efficiency-release targets that simultaneously incorporate the short diffusion lengths, high permeabilities, controllable temperatures, and heat removal properties required for the generation of useful radioactive ion beam (RIB) intensities for nuclear physics and astrophysics research using the isotope separation on-line (ISOL) technique. Short diffusion lengths are achieved either by using thin fibrous target materials or by coating thin layers of selected target material onto low-density carbon fibers such as reticulated vitreous carbon fiber (RVCF) or carbon-bonded-carbon-fiber (CBCF) to form highly permeable composite target matrices. Computational studies which simulate the generation and removal of primary beam deposited heat from target materials have been conducted to optimize the design of target/heat-sink systems for generating RIBs. The results derived from diffusion release-rate simulation studies for selected targets and thermal analyses of temperature distributions within a prototype target/heat-sink system subjected to primary ion beam irradiation will be presented in this report.

Space Station

NASA Image and Video Library

1985-12-01

Skylab's success proved that scientific experimentation in a low gravity environment was essential to scientific progress. A more permanent structure was needed to provide this space laboratory. President Ronald Reagan, on January 25, 1984, during his State of the Union address, claimed that the United States should exploit the new frontier of space, and directed NASA to build a permanent marned space station within a decade. The idea was that the space station would not only be used as a laboratory for the advancement of science and medicine, but would also provide a staging area for building a lunar base and manned expeditions to Mars and elsewhere in the solar system. President Reagan invited the international community to join with the United States in this endeavour. NASA and several countries moved forward with this concept. By December 1985, the first phase of the space station was well underway with the design concept for the crew compartments and laboratories. Pictured are two NASA astronauts, at Marshall Space Flight Center's (MSFC) Neutral Buoyancy Simulator (NBS), practicing construction techniques they later used to construct the space station after it was deployed.

Shuttle on-orbit rendezvous targeting: Circular orbits

NASA Technical Reports Server (NTRS)

Bentley, E. L.

1972-01-01

The strategy and logic used in a space shuttle on-orbit rendezvous targeting program are described. The program generates ascent targeting conditions for boost to insertion into an intermediate parking orbit, and generates on-orbit targeting and timeline bases for each maneuver to effect rendezvous with a space station. Time of launch is determined so as to eliminate any plane change, and all work was performed for a near-circular space station orbit.

Space station experiment definition: Long-term cryogenic fluid storage

NASA Technical Reports Server (NTRS)

Jetley, R. L.; Scarlotti, R. D.

1987-01-01

The conceptual design of a space station Technology Development Mission (TDM) experiment to demonstrate and evaluate cryogenic fluid storage and transfer technologies is presented. The experiment will be deployed on the initial operational capability (IOC) space station for a four-year duration. It is modular in design, consisting of three phases to test the following technologies: passive thermal technologies (phase 1), fluid transfer (phase 2), and active refrigeration (phase 3). Use of existing hardware was a primary consideration throughout the design effort. A conceptual design of the experiment was completed, including configuration sketches, system schematics, equipment specifications, and space station resources and interface requirements. These requirements were entered into the NASA Space Station Mission Data Base. A program plan was developed defining a twelve-year development and flight plan. Program cost estimates are given.

An Exploratory Exercise in Taguchi Analysis of Design Parameters: Application to a Shuttle-to-space Station Automated Approach Control System

NASA Technical Reports Server (NTRS)

Deal, Don E.

1991-01-01

The chief goals of the summer project have been twofold - first, for my host group and myself to learn as much of the working details of Taguchi analysis as possible in the time allotted, and, secondly, to apply the methodology to a design problem with the intention of establishing a preliminary set of near-optimal (in the sense of producing a desired response) design parameter values from among a large number of candidate factor combinations. The selected problem is concerned with determining design factor settings for an automated approach program which is to have the capability of guiding the Shuttle into the docking port of the Space Station under controlled conditions so as to meet and/or optimize certain target criteria. The candidate design parameters under study were glide path (i.e., approach) angle, path intercept and approach gains, and minimum impulse bit mode (a parameter which defines how Shuttle jets shall be fired). Several performance criteria were of concern: terminal relative velocity at the instant the two spacecraft are mated; docking offset; number of Shuttle jet firings in certain specified directions (of interest due to possible plume impingement on the Station's solar arrays), and total RCS (a measure of the energy expended in performing the approach/docking maneuver). In the material discussed here, we have focused on single performance criteria - total RCS. An analysis of the possibility of employing a multiobjective function composed of a weighted sum of the various individual criteria has been undertaken, but is, at this writing, incomplete. Results from the Taguchi statistical analysis indicate that only three of the original four posited factors are significant in affecting RCS response. A comparison of model simulation output (via Monte Carlo) with predictions based on estimated factor effects inferred through the Taguchi experiment array data suggested acceptable or close agreement between the two except at the predicted optimum

Preliminary PANSAT ground station software design and use of an expert system to analyze telemetry

NASA Astrophysics Data System (ADS)

Lawrence, Gregory W.

1994-03-01

The Petite Amateur Navy Satellite (PANSAT) is a communications satellite designed to be used by civilian amateur radio operators. A master ground station is being built at the Naval Postgraduate School. This computer system performs satellite commands, displays telemetry, trouble-shoots problems, and passes messages. The system also controls an open loop tracking antenna. This paper concentrates on the telemetry display, decoding, and interpretation through artificial intelligence (AI). The telemetry is displayed in an easily interpretable format, so that any user can understand the current health of the satellite and be cued as to any problems and possible solutions. Only the master ground station has the ability to receive all telemetry and send commands to the spacecraft; civilian ham users do not have access to this information. The telemetry data is decommutated and analyzed before it is displayed to the user, so that the raw data will not have to be interpreted by ground users. The analysis will use CLIPS imbedded in the code, and derive its inputs from telemetry decommutation. The program is an expert system using a forward chaining set of rules based on the expected operation and parameters of the satellite. By building the rules during the construction and design of the satellite, the telemetry can be well understood and interpreted after the satellite is launched and the designers may no longer be available to provide input to the problem.

Space Station ECLSS Integration Analysis

NASA Technical Reports Server (NTRS)

1993-01-01

The Space Station Environmental Control and Life Support System (ECLSS) contract with NASA MSFC covered the time frame from 9 May 1985 to 31 Dec. 1992. The contract roughly covered the period of Space Station Freedom (SSF) development from early Phase B through Phase C/D Critical Design Review (CDR). During this time, McDonnell Douglas Aerospace-Huntsville (formerly McDonnell Douglas Space Systems Company) performed an analytical support role to MSFC for the development of analytical math models and engineering trade studies related to the design of the ECLSS for the SSF.

Space station propulsion test bed

NASA Technical Reports Server (NTRS)

Briley, G. L.; Evans, S. A.

1989-01-01

A test bed was fabricated to demonstrate hydrogen/oxygen propulsion technology readiness for the intital operating configuration (IOC) space station application. The test bed propulsion module and computer control system were delivered in December 1985, but activation was delayed until mid-1986 while the propulsion system baseline for the station was reexamined. A new baseline was selected with hydrogen/oxygen thruster modules supplied with gas produced by electrolysis of waste water from the space shuttle and space station. As a result, an electrolysis module was designed, fabricated, and added to the test bed to provide an end-to-end simulation of the baseline system. Subsequent testing of the test bed propulsion and electrolysis modules provided an end-to-end demonstration of the complete space station propulsion system, including thruster hot firings using the oxygen and hydrogen generated from electrolysis of water. Complete autonomous control and operation of all test bed components by the microprocessor control system designed and delivered during the program was demonstrated. The technical readiness of the system is now firmly established.

Nutrient cycling Microbial Ecosystems: Assembly, Function and Targeted Design

DTIC Science & Technology

2017-05-05

different chemical transformations, converting potentially harmful chemicals via a series of intermediates, to harmless waste products. This shuttling of...Report: Nutrient-cycling Microbial Ecosystems: Assembly, Function and Targeted Design The views, opinions and/or findings contained in this report...are those of the author(s) and should not contrued as an official Department of the Army position, policy or decision, unless so designated by other

Space Station data management system architecture

NASA Technical Reports Server (NTRS)

Mallary, William E.; Whitelaw, Virginia A.

1987-01-01

Within the Space Station program, the Data Management System (DMS) functions in a dual role. First, it provides the hardware resources and software services which support the data processing, data communications, and data storage functions of the onboard subsystems and payloads. Second, it functions as an integrating entity which provides a common operating environment and human-machine interface for the operation and control of the orbiting Space Station systems and payloads by both the crew and the ground operators. This paper discusses the evolution and derivation of the requirements and issues which have had significant effect on the design of the Space Station DMS, describes the DMS components and services which support system and payload operations, and presents the current architectural view of the system as it exists in October 1986; one-and-a-half years into the Space Station Phase B Definition and Preliminary Design Study.

Design and Fabrication of Opacity Targets for the National Ignition Facility

DOE PAGES

Cardenas, Tana; Schmidt, Derek William; Dodd, Evan S.; ...

2017-12-22

Accurate models for opacity of partially ionized atoms are important for modeling and understanding stellar interiors and other high-energy-density phenomena such as inertial confinement fusion. Lawrence Livermore National Laboratory is leading a multilaboratory effort to conduct experiments on the National Ignition Facility (NIF) to try to reproduce recent opacity tests at the Sandia National Laboratory Z-facility. Since 2015, the NIF effort has evolved several hohlraum designs that consist of multiple pieces joined together. The target also has three components attached to the main stalk over a long distance with high tolerances that have resulted in several design iterations. The targetmore » has made use of rapid prototyped features to attach a capsule and collimator under the hohlraum while avoiding interference with the beams. Furthermore, this paper discusses the evolution of the hohlraum and overall target design and the challenges involved with fabricating and assembling these targets.« less

Design and Fabrication of Opacity Targets for the National Ignition Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cardenas, Tana; Schmidt, Derek William; Dodd, Evan S.

Accurate models for opacity of partially ionized atoms are important for modeling and understanding stellar interiors and other high-energy-density phenomena such as inertial confinement fusion. Lawrence Livermore National Laboratory is leading a multilaboratory effort to conduct experiments on the National Ignition Facility (NIF) to try to reproduce recent opacity tests at the Sandia National Laboratory Z-facility. Since 2015, the NIF effort has evolved several hohlraum designs that consist of multiple pieces joined together. The target also has three components attached to the main stalk over a long distance with high tolerances that have resulted in several design iterations. The targetmore » has made use of rapid prototyped features to attach a capsule and collimator under the hohlraum while avoiding interference with the beams. Furthermore, this paper discusses the evolution of the hohlraum and overall target design and the challenges involved with fabricating and assembling these targets.« less

Design of the hairpin ribozyme for targeting specific RNA sequences.

PubMed

Hampel, A; DeYoung, M B; Galasinski, S; Siwkowski, A

1997-01-01

The following steps should be taken when designing the hairpin ribozyme to cleave a specific target sequence: 1. Select a target sequence containing BN*GUC where B is C, G, or U. 2. Select the target sequence in areas least likely to have extensive interfering structure. 3. Design the conventional hairpin ribozyme as shown in Fig. 1, such that it can form a 4 bp helix 2 and helix 1 lengths up to 10 bp. 4. Synthesize this ribozyme from single-stranded DNA templates with a double-stranded T7 promoter. 5. Prepare a series of short substrates capable of forming a range of helix 1 lengths of 5-10 bp. 6. Identify these by direct RNA sequencing. 7. Assay the extent of cleavage of each substrate to identify the optimal length of helix 1. 8. Prepare the hairpin tetraloop ribozyme to determine if catalytic efficiency can be improved.

Space station operations management

NASA Technical Reports Server (NTRS)

Cannon, Kathleen V.

1989-01-01

Space Station Freedom operations management concepts must be responsive to the unique challenges presented by the permanently manned international laboratory. Space Station Freedom will be assembled over a three year period where the operational environment will change as significant capability plateaus are reached. First Element Launch, Man-Tended Capability, and Permanent Manned Capability, represent milestones in operational capability that is increasing toward mature operations capability. Operations management concepts are being developed to accomodate the varying operational capabilities during assembly, as well as the mature operational environment. This paper describes operations management concepts designed to accomodate the uniqueness of Space Station Freedoom, utilizing tools and processes that seek to control operations costs.

A shuttle and space station manipulator system for assembly, docking, maintenance, cargo handling and spacecraft retrieval (preliminary design). Volume 3: Concept analysis. Part 1: Technical

NASA Technical Reports Server (NTRS)

1972-01-01

Information backing up the key features of the manipulator system concept and detailed technical information on the subsystems are presented. Space station assembly and shuttle cargo handling tasks are emphasized in the concept analysis because they involve shuttle berthing, transferring the manipulator boom between shuttle and station, station assembly, and cargo handling. Emphasis is also placed on maximizing commonality in the system areas of manipulator booms, general purpose end effectors, control and display, data processing, telemetry, dedicated computers, and control station design.

International Space Station (ISS)

NASA Image and Video Library

2001-02-16

The International Space Station (ISS), with its newly attached U.S. Laboratory, Destiny, was photographed by a crew member aboard the Space Shuttle Orbiter Atlantis during a fly-around inspection after Atlantis separated from the Space Station. The Laboratory is shown in the foreground of this photograph. The American-made Destiny module is the cornerstone for space-based research aboard the orbiting platform and the centerpiece of the International Space Station (ISS), where unprecedented science experiments will be performed in the near-zero gravity of space. Destiny will also serve as the command and control center for the ISS. The aluminum module is 8.5-meters (28-feet) long and 4.3-meters (14-feet) in diameter. The laboratory consists of three cylindrical sections and two endcones with hatches that will be mated to other station components. A 50.9-centimeter (20-inch-) diameter window is located on one side of the center module segment. This pressurized module is designed to accommodate pressurized payloads. It has a capacity of 24 rack locations. Payload racks will occupy 15 locations especially designed to support experiments. The Destiny module was built by the Boeing Company under the direction of the Marshall Space Flight Center.

International Space Station (ISS)

NASA Image and Video Library

2001-02-16

With its new U.S. Laboratory, Destiny, contrasted over a blue and white Earth, the International Space Station (ISS) was photographed by one of the STS-98 crew members aboard the Space Shuttle Atlantis following separation of the Shuttle and Station. The Laboratory is shown at the lower right of the Station. The American-made Destiny module is the cornerstone for space-based research aboard the orbiting platform and the centerpiece of the ISS, where unprecedented science experiments will be performed in the near-zero gravity of space. Destiny will also serve as the command and control center for the ISS. The aluminum module is 8.5- meters (28-feet) long and 4.3-meters (14-feet) in diameter. The laboratory consists of three cylindrical sections and two endcones with hatches that will be mated to other station components. A 50.9-centimeter (20-inch-) diameter window is located on one side of the center module segment. This pressurized module is designed to accommodate pressurized payloads. It has a capacity of 24 rack locations. Payload racks will occupy 15 locations especially designed to support experiments. The Destiny module was built by the Boeing Company under the direction of the Marshall Space Flight Center.

PrimerStation: a highly specific multiplex genomic PCR primer design server for the human genome

PubMed Central

Yamada, Tomoyuki; Soma, Haruhiko; Morishita, Shinichi

2006-01-01

PrimerStation () is a web service that calculates primer sets guaranteeing high specificity against the entire human genome. To achieve high accuracy, we used the hybridization ratio of primers in liquid solution. Calculating the status of sequence hybridization in terms of the stringent hybridization ratio is computationally costly, and no web service checks the entire human genome and returns a highly specific primer set calculated using a precise physicochemical model. To shorten the response time, we precomputed candidates for specific primers using a massively parallel computer with 100 CPUs (SunFire 15 K) about 3 months in advance. This enables PrimerStation to search and output qualified primers interactively. PrimerStation can select highly specific primers suitable for multiplex PCR by seeking a wider temperature range that minimizes the possibility of cross-reaction. It also allows users to add heuristic rules to the primer design, e.g. the exclusion of single nucleotide polymorphisms (SNPs) in primers, the avoidance of poly(A) and CA-repeats in the PCR products, and the elimination of defective primers using the secondary structure prediction. We performed several tests to verify the PCR amplification of randomly selected primers for ChrX, and we confirmed that the primers amplify specific PCR products perfectly. PMID:16845094

Optimizing Placement of Weather Stations: Exploring Objective Functions of Meaningful Combinations of Multiple Weather Variables

NASA Astrophysics Data System (ADS)

Snyder, A.; Dietterich, T.; Selker, J. S.

2017-12-01

Many regions of the world lack ground-based weather data due to inadequate or unreliable weather station networks. For example, most countries in Sub-Saharan Africa have unreliable, sparse networks of weather stations. The absence of these data can have consequences on weather forecasting, prediction of severe weather events, agricultural planning, and climate change monitoring. The Trans-African Hydro-Meteorological Observatory (TAHMO.org) project seeks to address these problems by deploying and operating a large network of weather stations throughout Sub-Saharan Africa. To design the TAHMO network, we must determine where to place weather stations within each country. We should consider how we can create accurate spatio-temporal maps of weather data and how to balance the desired accuracy of each weather variable of interest (precipitation, temperature, relative humidity, etc.). We can express this problem as a joint optimization of multiple weather variables, given a fixed number of weather stations. We use reanalysis data as the best representation of the "true" weather patterns that occur in the region of interest. For each possible combination of sites, we interpolate the reanalysis data between selected locations and calculate the mean average error between the reanalysis ("true") data and the interpolated data. In order to formulate our multi-variate optimization problem, we explore different methods of weighting each weather variable in our objective function. These methods include systematic variation of weights to determine which weather variables have the strongest influence on the network design, as well as combinations targeted for specific purposes. For example, we can use computed evapotranspiration as a metric that combines many weather variables in a way that is meaningful for agricultural and hydrological applications. We compare the errors of the weather station networks produced by each optimization problem formulation. We also compare these

49 CFR 192.201 - Required capacity of pressure relieving and limiting stations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Design of Pipeline Components § 192.201 Required capacity of pressure relieving and limiting stations. (a) Each pressure relief station or pressure limiting station or group of those stations installed to... part of the pipeline or distribution system in excess of those for which it was designed, or against...

DESIGNING AN OPPORTUNITY FUEL WITH BIOMASS AND TIRE-DERIVED FUEL FOR COFIRING AT WILLOW ISLAND GENERATING STATION AND COFIRING SAWDUST WITH COAL AT ALBRIGHT GENERATING STATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

K. Payette; D. Tillman

During the period October 1, 2002--December 31, 2002, Allegheny Energy Supply Co., LLC (Allegheny) completed the first year of testing at the Willow Island cofiring project. This included data acquisition and analysis associated with certain operating parameters and environmental results. Over 2000 hours of cofiring operation were logged at Willow Island, and about 4,000 tons of sawdust were burned along with slightly more tire-derived fuel (TDF). The results were generally favorable. During this period, also, a new grinder was ordered for the Albright Generating Station to handle oversized material rejected by the disc screen. This report summarizes the activities associatedmore » with the Designer Opportunity Fuel program, and demonstrations at Willow Island and Albright Generating Stations. It details the test results at Willow Island and summarizes the grinder program at Albright.« less

Theoretical study on the effect of the design of small (milli-Newton) thruster jets on molecular contamination for the space station

NASA Technical Reports Server (NTRS)

Riley, B. R.

1986-01-01

The self-induced molecular contamination around the space station could have adverse effects on space station components (for example solar panels) as well as scientific experiments that might be done on or near the space station. Aerospace engineers need to design a space station (SS) propulsion system that keeps the SS in a stable orbit and at the same time does not allow the propellant gases to interfere with the experiments of the user. One scenario that might accomplish the above requirements is to use an electrothermal propulsion system, resistojet, that will thrust continuously in the hundreds of milli-Newton range which will provide a constant altitude for the SS with a low g environment. As a first attempt to understand the contamination from such a propulsion system, a point source model was developed. The numerical results of the point source model are given. Number column densities for CO2 are presented as a function of direction of observation (line of sight), temperature of the exit gas, and mean exit velocity. All the results are for a constant exhaust rate of 5,000 kg/year. In addition, a mathematical model to study the effect of nozzle design on the induced molecular environment around the space station produced by simple gas propellants is described. The mathematical model would allow one to follow the expansion of the gas from the throat of a nozzle to the nozzle exit plane and then into the space external to the nozzle.

Space Station Freedom food management

NASA Technical Reports Server (NTRS)

Whitehurst, Troy N., Jr.; Bourland, Charles T.

1992-01-01

This paper summarizes the specification requirements for the Space Station Food System, and describes the system that is being designed and developed to meet those requirements. Space Station Freedom will provide a mix of frozen, refrigerated, rehydratable, and shelf stable foods. The crew will pre-select preferred foods from an approved list, to the extent that proper nutrition balance is maintained. A galley with freezers, refrigerators, trash compactor, and combination microwave and convection ovens will improve crew efficiency and productivity during the long Space Station Freedom (SSF) missions.

Design of a reusable kinetic energy absorber for an astronaut safety tether to be used during extravehicular activities on the Space Station

NASA Technical Reports Server (NTRS)

Borthwick, Dawn E.; Cronch, Daniel F.; Nixon, Glen R.

1991-01-01

The goal of this project is to design a reusable safety device for a waist tether which will absorb the kinetic energy of an astronaut drifting away from the Space Station. The safety device must limit the tension of the tether line in order to prevent damage to the astronaut's space suit or to the structure of the spacecraft. The tether currently used on shuttle missions must be replaced after the safety feature has been developed. A reusable tether for the Space Station would eliminate the need for replacement tethers, conserving space and mass. This report presents background information, scope and limitations, methods of research and development, alternative designs, a final design solution and its evaluation, and recommendations for further work.

A modular Space Station/Base electrical power system - Requirements and design study.

NASA Technical Reports Server (NTRS)

Eliason, J. T.; Adkisson, W. B.

1972-01-01

The requirements and procedures necessary for definition and specification of an electrical power system (EPS) for the future space station are discussed herein. The considered space station EPS consists of a replaceable main power module with self-contained auxiliary power, guidance, control, and communication subsystems. This independent power source may 'plug into' a space station module which has its own electrical distribution, control, power conditioning, and auxiliary power subsystems. Integration problems are discussed, and a transmission system selected with local floor-by-floor power conditioning and distribution in the station module. This technique eliminates the need for an immediate long range decision on the ultimate space base power sources by providing capability for almost any currently considered option.

Pharmacophore based design of some multi-targeted compounds targeted against pathways of diabetic complications.

PubMed

Chadha, Navriti; Silakari, Om

2017-09-01

Diabetic complications is a complex metabolic disorder developed primarily due to prolonged hyperglycemia in the body. The complexity of the disease state as well as the unifying pathophysiology discussed in the literature reports exhibited that the use of multi-targeted agents with multiple complementary biological activities may offer promising therapy for the intervention of the disease over the single-target drugs. In the present study, novel thiazolidine-2,4-dione analogues were designed as multi-targeted agents implicated against the molecular pathways involved in diabetic complications using knowledge based as well as in-silico approaches such as pharmacophore mapping, molecular docking etc. The hit molecules were duly synthesized and biochemical estimation of these molecules against aldose reductase (ALR2), protein kinase Cβ (PKCβ) and poly (ADP-ribose) polymerase 1 (PARP-1) led to identification of compound 2 that showed good potency against PARP-1 and ALR2 enzymes. These positive results support the progress of a low cost multi-targeted agent with putative roles in diabetic complications. Copyright © 2017 Elsevier Inc. All rights reserved.

Design and Verification of Space Station EVA-Operated Truss Attachment System

NASA Technical Reports Server (NTRS)

Katell, Gabriel

2001-01-01

This paper describes the design and verification of a system used to attach two segments of the International Space Station (ISS). This system was first used in space to mate the P6 and Z1 trusses together in December 2000, through a combination of robotic and extravehicular tasks. Features that provided capture, coarse alignment, and fine alignment during the berthing process are described. Attachment of this high value hardware was critical to the ISS's sequential assembly, necessitating the inclusion of backup design and operational features. Astronauts checked for the proper performance of the alignment and bolting features during on-orbit operations. During berthing, the system accommodates truss-to-truss relative displacements that are caused by manufacturing tolerances and on-orbit thermal gradients. After bolt installation, the truss interface becomes statically determinate with respect to in-plane shear loads and isolates attach bolts from bending moments. The approach used to estimate relative displacements and the means of accommodating them is explained. Confidence in system performance was achieved through a cost-effective collection of tests and analyses, including thermal, structural, vibration, misalignment, contact dynamics, underwater simulation, and full-scale functional testing. Design considerations that have potential application to other mechanisms include accommodating variations of friction coefficients in the on-orbit joints, wrench torque tolerances, joint preload, moving element clearances at temperature extremes, and bolt-nut torque reaction.

Estimating soil temperature using neighboring station data via multi-nonlinear regression and artificial neural network models.

PubMed

Bilgili, Mehmet; Sahin, Besir; Sangun, Levent

2013-01-01

The aim of this study is to estimate the soil temperatures of a target station using only the soil temperatures of neighboring stations without any consideration of the other variables or parameters related to soil properties. For this aim, the soil temperatures were measured at depths of 5, 10, 20, 50, and 100 cm below the earth surface at eight measuring stations in Turkey. Firstly, the multiple nonlinear regression analysis was performed with the "Enter" method to determine the relationship between the values of target station and neighboring stations. Then, the stepwise regression analysis was applied to determine the best independent variables. Finally, an artificial neural network (ANN) model was developed to estimate the soil temperature of a target station. According to the derived results for the training data set, the mean absolute percentage error and correlation coefficient ranged from 1.45% to 3.11% and from 0.9979 to 0.9986, respectively, while corresponding ranges of 1.685-3.65% and 0.9988-0.9991, respectively, were obtained based on the testing data set. The obtained results show that the developed ANN model provides a simple and accurate prediction to determine the soil temperature. In addition, the missing data at the target station could be determined within a high degree of accuracy.

Space Station Freedom electrical performance model

NASA Technical Reports Server (NTRS)

Hojnicki, Jeffrey S.; Green, Robert D.; Kerslake, Thomas W.; Mckissock, David B.; Trudell, Jeffrey J.

1993-01-01

The baseline Space Station Freedom electric power system (EPS) employs photovoltaic (PV) arrays and nickel hydrogen (NiH2) batteries to supply power to housekeeping and user electrical loads via a direct current (dc) distribution system. The EPS was originally designed for an operating life of 30 years through orbital replacement of components. As the design and development of the EPS continues, accurate EPS performance predictions are needed to assess design options, operating scenarios, and resource allocations. To meet these needs, NASA Lewis Research Center (LeRC) has, over a 10 year period, developed SPACE (Station Power Analysis for Capability Evaluation), a computer code designed to predict EPS performance. This paper describes SPACE, its functionality, and its capabilities.

Enabler operator station. [lunar surface vehicle

NASA Technical Reports Server (NTRS)

Bailey, Andrea; Keitzman, John; King, Shirlyn; Stover, Rae; Wegner, Torsten

1992-01-01

The objective of this project was to design an onboard operator station for the conceptual Lunar Work Vehicle (LWV). This LWV would be used in the colonization of a lunar outpost. The details that follow, however, are for an earth-bound model. Several recommendations are made in the appendix as to the changes needed in material selection for the lunar environment. The operator station is designed dimensionally correct for an astronaut wearing the current space shuttle EVA suit (which includes life support). The proposed operator station will support and restrain an astronaut as well as provide protection from the hazards of vehicle rollover. The threat of suit puncture is eliminated by rounding all corners and edges. A step-plate, located at the front of the vehicle, provides excellent ease of entry and exit. The operator station weight requirements are met by making efficient use of grid members, semi-rigid members and woven fabrics.

New designs of LMJ targets for early ignition experiments

NASA Astrophysics Data System (ADS)

C-Clérouin, C.; Bonnefille, M.; Dattolo, E.; Fremerye, P.; Galmiche, D.; Gauthier, P.; Giorla, J.; Laffite, S.; Liberatore, S.; Loiseau, P.; Malinie, G.; Masse, L.; Poggi, F.; Seytor, P.

2008-05-01

The LMJ experimental plans include the attempt of ignition and burn of an ICF capsule with 40 laser quads, delivering up to 1.4MJ and 380TW. New targets needing reduced laser energy with only a small decrease in robustness are then designed for this purpose. A first strategy is to use scaled-down cylindrical hohlraums and capsules, taking advantage of our better understanding of the problem, set on theoretical modelling, simulations and experiments. Another strategy is to work specifically on the coupling efficiency parameter, i.e. the ratio of the energy absorbed by the capsule to the laser energy, which is with parametric instabilities a crucial drawback of indirect drive. An alternative design is proposed, made up of the nominal 60 quads capsule, named A1040, in a rugby-shaped hohlraum. Robustness evaluations of these different targets are in progress.

Instructor/Operator Station Design Handbook for Aircrew Training Devices. Final Technical Report for Period March 1982-December 1986.

ERIC Educational Resources Information Center

Warner, H. D.

Human engineering guidelines for the design of instructor/operator stations (IOSs) for aircrew training devices are provided in this handbook. These guidelines specify the preferred configuration of IOS equipment across the range of the anticipated user sizes and performance capabilities. The guidelines are consolidated from various human…

Human factors in space station architecture 1: Space station program implications for human factors research

NASA Technical Reports Server (NTRS)

Cohen, M. M.

1985-01-01

The space station program is based on a set of premises on mission requirements and the operational capabilities of the space shuttle. These premises will influence the human behavioral factors and conditions on board the space station. These include: launch in the STS Orbiter payload bay, orbital characteristics, power supply, microgravity environment, autonomy from the ground, crew make-up and organization, distributed command control, safety, and logistics resupply. The most immediate design impacts of these premises will be upon the architectural organization and internal environment of the space station.

Designing a handwashing station for infrastructure-restricted communities in Bangladesh using the integrated behavioural model for water, sanitation and hygiene interventions (IBM-WASH)

PubMed Central

2013-01-01

Background In Bangladesh diarrhoeal disease and respiratory infections contribute significantly to morbidity and mortality. Handwashing with soap reduces the risk of infection; however, handwashing rates in infrastructure-restricted settings remain low. Handwashing stations – a dedicated, convenient location where both soap and water are available for handwashing – are associated with improved handwashing practices. Our aim was to identify a locally feasible and acceptable handwashing station that enabled frequent handwashing for two subsequent randomized trials testing the health effects of this behaviour. Methods We conducted formative research in the form of household trials of improved practices in urban and rural Bangladesh. Seven candidate handwashing technologies were tested by nine to ten households each during two iterative phases. We conducted interviews with participants during an introductory visit and two to five follow up visits over two to six weeks, depending on the phase. We used the Integrated Behavioural Model for Water, Sanitation and Hygiene (IBM-WASH) to guide selection of candidate handwashing stations and data analysis. Factors presented in the IBM-WASH informed thematic coding of interview transcripts and contextualized feasibility and acceptability of specific handwashing station designs. Results Factors that influenced selection of candidate designs were market availability of low cost, durable materials that were easy to replace or replenish in an infrastructure-restricted and shared environment. Water storage capacity, ease of use and maintenance, and quality of materials determined the acceptability and feasibility of specific handwashing station designs. After examining technology, psychosocial and contextual factors, we selected a handwashing system with two different water storage capacities, each with a tap, stand, basin, soapy water bottle and detergent powder for pilot testing in preparation for the subsequent randomized

Space Station personal hygiene study

NASA Technical Reports Server (NTRS)

Prejean, Stephen E.; Booher, Cletis R.

1986-01-01

A personal hygiene system is currently under development for Space Station application that will provide capabilities equivalent to those found on earth. This paper addresses the study approach for specifying both primary and contingency personal hygiene systems and provisions for specified growth. Topics covered are system definition and subsystem descriptions. Subsystem interfaces are explored to determine which concurrent NASA study efforts must be monitored during future design phases to stay up-to-date on critical Space Station parameters. A design concept for a three (3) compartment personal hygiene facility is included as a baseline for planned test and verification activities.

Monitoring productivity with multiple mist-net stations

Treesearch

C. John Ralph; Kimberly Hollinger; Sherri L. Miller

2004-01-01

We evaluated data from 22 mist-net capture stations operated over 5 to 13 years in northern California and southern Oregon, to help develop sampling designs for monitoring using mist nets. In summer, 2.6% of individuals were recaptured at other stations within 1 km of the original banding station, and in fall, 1.4% were recaptured nearby. We recommend...

A navigation and control system for an autonomous rescue vehicle in the space station environment

NASA Technical Reports Server (NTRS)

Merkel, Lawrence

1991-01-01

A navigation and control system was designed and implemented for an orbital autonomous rescue vehicle envisioned to retrieve astronauts or equipment in the case that they become disengaged from the space station. The rescue vehicle, termed the Extra-Vehicular Activity Retriever (EVAR), has an on-board inertial measurement unit ahd GPS receivers for self state estimation, a laser range imager (LRI) and cameras for object state estimation, and a data link for reception of space station state information. The states of the retriever and objects (obstacles and the target object) are estimated by inertial state propagation which is corrected via measurements from the GPS, the LRI system, or the camera system. Kalman filters are utilized to perform sensor fusion and estimate the state propagation errors. Control actuation is performed by a Manned Maneuvering Unit (MMU). Phase plane control techniques are used to control the rotational and translational state of the retriever. The translational controller provides station-keeping or motion along either Clohessy-Wiltshire trajectories or straight line trajectories in the LVLH frame of any sufficiently observed object or of the space station. The software was used to successfully control a prototype EVAR on an air bearing floor facility, and a simulated EVAR operating in a simulated orbital environment. The design of the navigation system and the control system are presented. Also discussed are the hardware systems and the overall software architecture.

Implementation of ionizing radiation environment requirements for Space Station

NASA Technical Reports Server (NTRS)

Boeder, Paul A.; Watts, John W.

1993-01-01

Proper functioning of Space Station hardware requires that the effects of high-energy ionizing particles from the natural environment and (possibly) from man-made sources be considered during design. At the Space Station orbit of 28.5-deg inclination and 330-440 km altitude, geomagnetically trapped protons and electrons contribute almost all of the dose, while galactic cosmic rays and anomalous cosmic rays may produce Single Event Upsets (SEUs), latchups, and burnouts of microelectronic devices. Implementing ionizing radiation environment requirements for Space Station has been a two part process, including the development of a description of the environment for imposing requirements on the design and the development of a control process for assessing how well the design addresses the effects of the ionizing radiation environment. We will review both the design requirements and the control process for addressing ionizing radiation effects on Space Station.

Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction

PubMed Central

2012-01-01

Background Choosing appropriate primers is probably the single most important factor affecting the polymerase chain reaction (PCR). Specific amplification of the intended target requires that primers do not have matches to other targets in certain orientations and within certain distances that allow undesired amplification. The process of designing specific primers typically involves two stages. First, the primers flanking regions of interest are generated either manually or using software tools; then they are searched against an appropriate nucleotide sequence database using tools such as BLAST to examine the potential targets. However, the latter is not an easy process as one needs to examine many details between primers and targets, such as the number and the positions of matched bases, the primer orientations and distance between forward and reverse primers. The complexity of such analysis usually makes this a time-consuming and very difficult task for users, especially when the primers have a large number of hits. Furthermore, although the BLAST program has been widely used for primer target detection, it is in fact not an ideal tool for this purpose as BLAST is a local alignment algorithm and does not necessarily return complete match information over the entire primer range. Results We present a new software tool called Primer-BLAST to alleviate the difficulty in designing target-specific primers. This tool combines BLAST with a global alignment algorithm to ensure a full primer-target alignment and is sensitive enough to detect targets that have a significant number of mismatches to primers. Primer-BLAST allows users to design new target-specific primers in one step as well as to check the specificity of pre-existing primers. Primer-BLAST also supports placing primers based on exon/intron locations and excluding single nucleotide polymorphism (SNP) sites in primers. Conclusions We describe a robust and fully implemented general purpose primer design tool

Conceptual design and analysis of a dynamic scale model of the Space Station Freedom

NASA Technical Reports Server (NTRS)

Davis, D. A.; Gronet, M. J.; Tan, M. K.; Thorne, J.

1994-01-01

This report documents the conceptual design study performed to evaluate design options for a subscale dynamic test model which could be used to investigate the expected on-orbit structural dynamic characteristics of the Space Station Freedom early build configurations. The baseline option was a 'near-replica' model of the SSF SC-7 pre-integrated truss configuration. The approach used to develop conceptual design options involved three sets of studies: evaluation of the full-scale design and analysis databases, conducting scale factor trade studies, and performing design sensitivity studies. The scale factor trade study was conducted to develop a fundamental understanding of the key scaling parameters that drive design, performance and cost of a SSF dynamic scale model. Four scale model options were estimated: 1/4, 1/5, 1/7, and 1/10 scale. Prototype hardware was fabricated to assess producibility issues. Based on the results of the study, a 1/4-scale size is recommended based on the increased model fidelity associated with a larger scale factor. A design sensitivity study was performed to identify critical hardware component properties that drive dynamic performance. A total of 118 component properties were identified which require high-fidelity replication. Lower fidelity dynamic similarity scaling can be used for non-critical components.

Galileo Station Keeping Strategy

NASA Technical Reports Server (NTRS)

Perez-Cambriles, Antonio; Bejar-Romero, Juan Antonio; Aguilar-Taboada, Daniel; Perez-Lopez, Fernando; Navarro, Daniel

2007-01-01

This paper presents analyses done for the design and implementation of the Maneuver Planning software of the Galileo Flight Dynamics Facility. The station keeping requirements of the constellation have been analyzed in order to identify the key parameters to be taken into account in the design and implementation of the software.

The space station assembly phase: System design trade-offs for the flight telerobotic servicer

NASA Technical Reports Server (NTRS)

Smith, Jeffrey H.; Gyamfi, Max; Volkmer, Kent; Zimmerman, Wayne

1988-01-01

The effects of a recent study aimed at identifying key issues and trade-offs associated with using a Flight Telerobotic Servicer (FTS) to aid in Space Station assembly-phase tasks is described. The use of automation and robotic (A and R) technologies for large space systems often involves a substitution of automation capabilities for human EVA or IVA activities. A methodology is presented that incorporates assessment of candidate assembly-phase tasks, telerobotic performance capabilities, development costs, and effects of operational constaints. Changes in the region of cost-effectiveness are examined under a variety of system design assumptions. A discussion of issues is presented with focus on three roles the FTS might serve: as a research-oriented test bed to learn more about space usage of telerobotics; as a research based test bed having an experimental demonstration orientation with limited assembly and servicing applications; or as an operational system to augment EVA and to aid construction of the Space Station and to reduce the program (schedule) risk by increasing the flexibility of mission operations.

Space Station - An integrated approach to operational logistics support

NASA Technical Reports Server (NTRS)

Hosmer, G. J.

1986-01-01

Development of an efficient and cost effective operational logistics system for the Space Station will require logistics planning early in the program's design and development phase. This paper will focus on Integrated Logistics Support (ILS) Program techniques and their application to the Space Station program design, production and deployment phases to assure the development of an effective and cost efficient operational logistics system. The paper will provide the methodology and time-phased programmatic steps required to establish a Space Station ILS Program that will provide an operational logistics system based on planned Space Station program logistics support.

International Space Station (ISS)

NASA Image and Video Library

1997-11-26

This photograph shows the U.S. Laboratory Module (also called Destiny) for the International Space Station (ISS), under construction in the Space Station manufacturing facility at the Marshall Space Flight Center. The U.S. Laboratory module is the centerpiece of the ISS, where science experiments will be performed in the near-zero gravity of space. The Destiny Module was launched aboard the Space Shuttle orbiter Atlantis (STS-67 mission) on February 7, 2001. The aluminum module is 8.5 meters (28 feet) long and 4.3 meters (14 feet) in diameter. The laboratory consists of three cylindrical sections and two end cones with hatches that will be mated to other station components. A 50.9-centimeter- (20-inch-) diameter window is located on one side of the center module segment. This pressurized module is designed to accommodate pressurized payloads. It has a capacity of 24 rack locations, and payload racks will occupy 13 locations especially designed to support experiments. The ISS is a multidisciplinary laboratory, technology test bed, and observatory that will provide unprecedented undertakings in scientific, technological, and international experimentation.

DESIGNING AND OPPORTUNITY FUEL WITH BIOMASS AND TIRE-DERIVED FUEL FOR COFIRING AT WILLOW ISLAND GENERATING STATION AND COFIRING SAWDUST WITH COAL AT ALBRIGHT GENERATING STATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

K. Payette; D. Tillman

During the period July 1, 2000-March 31, 2004, Allegheny Energy Supply Co., LLC (Allegheny) conducted an extensive demonstration of woody biomass cofiring at its Willow Island and Albright Generating Stations. This demonstration, cofunded by USDOE and Allegheny, and supported by the Biomass Interest Group (BIG) of EPRI, evaluated the impacts of sawdust cofiring in both cyclone boilers and tangentially-fired pulverized coal boilers. The cofiring in the cyclone boiler--Willow Island Generating Station Unit No.2--evaluated the impacts of sawdust alone, and sawdust blended with tire-derived fuel. The biomass was blended with the coal on its way to the combustion system. The cofiringmore » in the pulverized coal boiler--Albright Generating Station--evaluated the impact of cofiring on emissions of oxides of nitrogen (NO{sub x}) when the sawdust was injected separately into the furnace. The demonstration of woody biomass cofiring involved design, construction, and testing at each site. The results addressed impacts associated with operational issues--capacity, efficiency, and operability--as well as formation and control of airborne emissions such as NO{sub x}, sulfur dioxide (SO{sub 2}2), opacity, and mercury. The results of this extensive program are detailed in this report.« less

Aiming Instruments On The Space Station

NASA Technical Reports Server (NTRS)

Estus, Jay M.; Laskin, Robert; Lin, Yu-Hwan

1989-01-01

Report discusses capabilities and requirements for aiming scientific instruments carried aboard proposed Space Station. Addresses two issues: whether system envisioned for pointing instruments at celestial targets offers sufficiently low jitter, high accuracy, and high stability to meet scientific requirements; whether it can do so even in presence of many vibrations and other disturbances on Space Station. Salient conclusion of study, recommendation to develop pointing-actuator system including mechanical/fluid base isolator underneath reactionaless gimbal subsystem. This kind of system offers greatest promise of high performance, cost-effectiveness, and modularity for job at hand.

The manned space station

NASA Astrophysics Data System (ADS)

Kovit, B.

The development and establishment of a manned space station represents the next major U.S. space program after the Space Shuttle. If all goes according to plan, the space station could be in orbit around the earth by 1992. A 'power tower' station configuration has been selected as a 'reference' design. This configuration involves a central truss structure to which various elements are attached. An eight-foot-square truss forms the backbone of a structure about 400 feet long. At its lower end, nearest the earth, are attached pressurized manned modules. These modules include two laboratory modules and two so-called 'habitat/command' modules, which provide living and working space for the projected crew of six persons. Later, the station's pressurized space would be expanded to accommodate up to 18 persons. By comparison, the Soviets will provide habitable space for 12 aboard a 300-ton station which they are expected to place in orbit. According to current plans the six U.S. astronauts will work in two teams of three persons each. A ninety-day tour of duty is considered.

A multiplex primer design algorithm for target amplification of continuous genomic regions.

PubMed

Ozturk, Ahmet Rasit; Can, Tolga

2017-06-19

Targeted Next Generation Sequencing (NGS) assays are cost-efficient and reliable alternatives to Sanger sequencing. For sequencing of very large set of genes, the target enrichment approach is suitable. However, for smaller genomic regions, the target amplification method is more efficient than both the target enrichment method and Sanger sequencing. The major difficulty of the target amplification method is the preparation of amplicons, regarding required time, equipment, and labor. Multiplex PCR (MPCR) is a good solution for the mentioned problems. We propose a novel method to design MPCR primers for a continuous genomic region, following the best practices of clinically reliable PCR design processes. On an experimental setup with 48 different combinations of factors, we have shown that multiple parameters might effect finding the first feasible solution. Increasing the length of the initial primer candidate selection sequence gives better results whereas waiting for a longer time to find the first feasible solution does not have a significant impact. We generated MPCR primer designs for the HBB whole gene, MEFV coding regions, and human exons between 2000 bp to 2100 bp-long. Our benchmarking experiments show that the proposed MPCR approach is able produce reliable NGS assay primers for a given sequence in a reasonable amount of time.

Design and Commissioning of a Transportable Laser Ranging Station STAR-C

NASA Astrophysics Data System (ADS)

Humbert, L.; Hasenohr, T.; Hampf, D.; Riede, W.

An increasing number of space debris and the rise of mega constellations as well as the deployment of small cost efficient satellites are a growing concern for space faring nations and their missions. Hence, a tight network of worldwide stations to support maintenance of catalogues for various tasks such as space surveillance tracking and space traffic management will significantly increase the reliability and availability of the collected data and therefore the safety of missions. A promising concept are transportable laser ranging stations in order to increase the number of observing stations and hence the coverage of the sky. Built and tested on a building test site they can be deployed to a desired site for operation. High energy laser with short pulses provide accurate ranging data to objects in space both cooperative and uncooperative, e.g. objects with a retroreflector and without one. This work introduces the progress of a transportable laser ranging station, of a Surveillance, Tracking and Ranging Container (STAR-C), built into a 20ft ISO container.

Space station molecular sieve development

NASA Technical Reports Server (NTRS)

Chang, C.; Rousseau, J.

1986-01-01

An essential function of a space environmental control system is the removal of carbon dioxide (CO2) from the atmosphere to control the partial pressure of this gas at levels lower than 3 mm Hg. The use of regenerable solid adsorbents for this purpose was demonstrated effectively during the Skylab mission. Earlier sorbent systems used zeolite molecular sieves. The carbon molecular sieve is a hydrophobic adsorbent with excellent potential for space station application. Although carbon molecular sieves were synthesized and investigated, these sieves were designed to simulate the sieving properties of 5A zeolite and for O2/N2 separation. This program was designed to develop hydrophobic carbon molecular sieves for CO2 removal from a space station crew environment. It is a first phase effort involved in sorbent material development and in demonstrating the utility of such a material for CO2 removal on space stations. The sieve must incorporate the following requirements: it must be hydrophobic; it must have high dynamic capacity for carbon dioxide at the low partial pressure of the space station atmosphere; and it must be chemiclly stable and will not generate contaminants.

Solar water heater for NASA's Space Station

NASA Technical Reports Server (NTRS)

Somers, Richard E.; Haynes, R. Daniel

1988-01-01

The feasibility of using a solar water heater for NASA's Space Station is investigated using computer codes developed to model the Space Station configuration, orbit, and heating systems. Numerous orbit variations, system options, and geometries for the collector were analyzed. Results show that a solar water heater, which would provide 100 percent of the design heating load and would not impose a significant impact on the Space Station overall design is feasible. A heat pipe or pumped fluid radial plate collector of about 10-sq m, placed on top of the habitat module was found to be well suited for satisfying water demand of the Space Station. Due to the relatively small area required by a radial plate, a concentrator is unnecessary. The system would use only 7 to 10 percent as much electricity as an electric water-heating system.

The space station: Human factors and productivity

NASA Technical Reports Server (NTRS)

Gillan, D. J.; Burns, M. J.; Nicodemus, C. L.; Smith, R. L.

1986-01-01

Human factor researchers and engineers are making inputs into the early stages of the design of the Space Station to improve both the quality of life and work on-orbit. Effective integration of the human factors information related to various Intravehicular Activity (IVA), Extravehicular Activity (EVA), and teletobotics systems during the Space Station design will result in increased productivity, increased flexibility of the Space Stations systems, lower cost of operations, improved reliability, and increased safety for the crew onboard the Space Station. The major features of productivity examined include the cognitive and physical effort involved in work, the accuracy of worker output and ability to maintain performance at a high level of accuracy, the speed and temporal efficiency with which a worker performs, crewmember satisfaction with their work environment, and the relation between performance and cost.

Space station control moment gyro control

NASA Technical Reports Server (NTRS)

Bordano, Aldo

1987-01-01

The potential large center-of-pressure to center-of-gravity offset of the space station makes the short term, within an orbit, variations in density of primary importance. The large range of uncertainty in the prediction of solar activity will penalize the design, developments, and operation of the space station.

Targeted proteins for diabetes drug design

NASA Astrophysics Data System (ADS)

Doan Trang Nguyen, Ngoc; Thi Le, Ly

2012-03-01

Type 2 diabetes mellitus is a common metabolism disorder characterized by high glucose in the bloodstream, especially in the case of insulin resistance and relative insulin deficiency. Nowadays, it is very common in middle-aged people and involves such dangerous symptoms as increasing risk of stroke, obesity and heart failure. In Vietnam, besides the common treatment of insulin injection, some herbal medication is used but no unified optimum remedy for the disease yet exists and there is no production of antidiabetic drugs in the domestic market yet. In the development of nanomedicine at the present time, drug design is considered as an innovative tool for researchers to study the mechanisms of diseases at the molecular level. The aim of this article is to review some common protein targets involved in type 2 diabetes, offering a new idea for designing new drug candidates to produce antidiabetic drugs against type 2 diabetes for Vietnamese people.

Modeling and system design for the LOFAR station digital processing

NASA Astrophysics Data System (ADS)

Alliot, Sylvain; van Veelen, Martijn

2004-09-01

In the context of the LOFAR preliminary design phase and in particular for the specification of the Station Digital Processing (SDP), a performance/cost model of the system was used. We present here the framework and the trajectory followed in this phase when going from requirements to specification. In the phased array antenna concepts for the next generation of radio telescopes (LOFAR, ATA, SKA) signal processing (multi-beaming and RFI mitigation) replaces the large antenna dishes. The embedded systems for these telescopes are major infrastructure cost items. Moreover, the flexibility and overall performance of the instrument depend greatly on them, therefore alternative solutions need to be investigated. In particular, the technology and the various data transport selections play a fundamental role in the optimization of the architecture. We proposed a formal method [1] of exploring these alternatives that has been followed during the SDP developments. Different scenarios were compared for the specification of the application (selection of the algorithms as well as detailed signal processing techniques) and in the specification of the system architecture (selection of high level topologies, platforms and components). It gave us inside knowledge on the possible trade-offs in the application and architecture domains. This was successful in providing firm basis for the design choices that are demanded by technical review committees.

Design and Implementation of the Automated Rendezvous Targeting Algorithms for Orion

NASA Technical Reports Server (NTRS)

DSouza, Christopher; Weeks, Michael

2010-01-01

The Orion vehicle will be designed to perform several rendezvous missions: rendezvous with the ISS in Low Earth Orbit (LEO), rendezvous with the EDS/Altair in LEO, a contingency rendezvous with the ascent stage of the Altair in Low Lunar Orbit (LLO) and a contingency rendezvous in LLO with the ascent and descent stage in the case of an aborted lunar landing. Therefore, it is not difficult to realize that each of these scenarios imposes different operational, timing, and performance constraints on the GNC system. To this end, a suite of on-board guidance and targeting algorithms have been designed to meet the requirement to perform the rendezvous independent of communications with the ground. This capability is particularly relevant for the lunar missions, some of which may occur on the far side of the moon. This paper will describe these algorithms which are designed to be structured and arranged in such a way so as to be flexible and able to safely perform a wide variety of rendezvous trajectories. The goal of the algorithms is not to merely fly one specific type of canned rendezvous profile. Conversely, it was designed from the start to be general enough such that any type of trajectory profile can be flown.(i.e. a coelliptic profile, a stable orbit rendezvous profile, and a expedited LLO rendezvous profile, etc) all using the same rendezvous suite of algorithms. Each of these profiles makes use of maneuver types which have been designed with dual goals of robustness and performance. They are designed to converge quickly under dispersed conditions and they are designed to perform many of the functions performed on the ground today. The targeting algorithms consist of a phasing maneuver (NC), an altitude adjust maneuver (NH), and plane change maneuver (NPC), a coelliptic maneuver (NSR), a Lambert targeted maneuver, and several multiple-burn targeted maneuvers which combine one of more of these algorithms. The derivation and implementation of each of these

An AI Approach to Ground Station Autonomy for Deep Space Communications

NASA Technical Reports Server (NTRS)

Fisher, Forest; Estlin, Tara; Mutz, Darren; Paal, Leslie; Law, Emily; Stockett, Mike; Golshan, Nasser; Chien, Steve

1998-01-01

This paper describes an architecture for an autonomous deep space tracking station (DS-T). The architecture targets fully automated routine operations encompassing scheduling and resource allocation, antenna and receiver predict generation. track procedure generation from service requests, and closed loop control and error recovery for the station subsystems. This architecture has been validated by the construction of a prototype DS-T station, which has performed a series of demonstrations of autonomous ground station control for downlink services with NASA's Mars Global Surveyor (MGS).

Optimal design and operation of booster chlorination stations layout in water distribution systems.

PubMed

Ohar, Ziv; Ostfeld, Avi

2014-07-01

This study describes a new methodology for the disinfection booster design, placement, and operation problem in water distribution systems. Disinfectant residuals, which are in most cases chlorine residuals, are assumed to be sufficient to prevent growth of pathogenic bacteria, yet low enough to avoid taste and odor problems. Commonly, large quantities of disinfectants are released at the sources outlets for preserving minimum residual disinfectant concentrations throughout the network. Such an approach can cause taste and odor problems near the disinfectant injection locations, but more important hazardous excessive disinfectant by-product formations (DBPs) at the far network ends, of which some may be carcinogenic. To cope with these deficiencies booster chlorination stations were suggested to be placed at the distribution system itself and not just at the sources, motivating considerable research in recent years on placement, design, and operation of booster chlorination stations in water distribution systems. The model formulated and solved herein is aimed at setting the required chlorination dose of the boosters for delivering water at acceptable residual chlorine and TTHM concentrations for minimizing the overall cost of booster placement, construction, and operation under extended period hydraulic simulation conditions through utilizing a multi-species approach. The developed methodology links a genetic algorithm with EPANET-MSX, and is demonstrated through base runs and sensitivity analyses on a network example application. Two approaches are suggested for dealing with water quality initial conditions and species periodicity: (1) repetitive cyclical simulation (RCS), and (2) cyclical constrained species (CCS). RCS was found to be more robust but with longer computational time. Copyright © 2014 Elsevier Ltd. All rights reserved.

International Space Station (ISS)

NASA Image and Video Library

2001-02-01

The Marshall Space Flight Center (MSFC) is responsible for designing and building the life support systems that will provide the crew of the International Space Station (ISS) a comfortable environment in which to live and work. Scientists and engineers at the MSFC are working together to provide the ISS with systems that are safe, efficient, and cost-effective. These compact and powerful systems are collectively called the Environmental Control and Life Support Systems, or simply, ECLSS. This photograph shows the development Water Processor located in two racks in the ECLSS test area at the Marshall Space Flight Center. Actual waste water, simulating Space Station waste, is generated and processed through the hardware to evaluate the performance of technologies in the flight Water Processor design.

The Capabilities of Space Stations

NASA Technical Reports Server (NTRS)

1995-01-01

Over the past two years the U.S. space station program has evolved to a three-phased international program, with the first phase consisting of the use of the U.S. Space Shuttle and the upgrading and use of the Russian Mir Space Station, and the second and third phases consisting of the assembly and use of the new International Space Station. Projected capabilities for research, and plans for utilization, have also evolved and it has been difficult for those not directly involved in the design and engineering of these space stations to learn and understand their technical details. The Committee on the Space Station of the National Research Council, with the concurrence of NASA, undertook to write this short report in order to provide concise and objective information on space stations and platforms -- with emphasis on the Mir Space Station and International Space Station -- and to supply a summary of the capabilities of previous, existing, and planned space stations. In keeping with the committee charter and with the task statement for this report, the committee has summarized the research capabilities of five major space platforms: the International Space Station, the Mir Space Station, the Space Shuttle (with a Spacelab or Spacehab module in its cargo bay), the Space Station Freedom (which was redesigned to become the International Space Station in 1993 and 1994), and Skylab. By providing the summary, together with brief descriptions of the platforms, the committee hopes to assist interested readers, including scientists and engineers, government officials, and the general public, in evaluating the utility of each system to meet perceived user needs.

Ligand design for riboswitches, an emerging target class for novel antibiotics.

PubMed

Rekand, Illimar Hugo; Brenk, Ruth

2017-09-01

Riboswitches are cis-acting gene regulatory elements and constitute potential targets for new antibiotics. Recent studies in this field have started to explore these targets for drug discovery. New ligands found by fragment screening, design of analogs of the natural ligands or serendipitously by phenotypic screening have shown antibacterial effects in cell assays against a range of bacteria strains and in animal models. In this review, we highlight the most advanced drug design work of riboswitch ligands and discuss the challenges in the field with respect to the development of antibiotics with a new mechanism of action.

Target-cancer-cell-specific activatable fluorescence imaging probes: rational design and in vivo applications.

PubMed

Kobayashi, Hisataka; Choyke, Peter L

2011-02-15

Conventional imaging methods, such as angiography, computed tomography (CT), magnetic resonance imaging (MRI), and radionuclide imaging, rely on contrast agents (iodine, gadolinium, and radioisotopes, for example) that are "always on." Although these indicators have proven clinically useful, their sensitivity is lacking because of inadequate target-to-background signal ratio. A unique aspect of optical imaging is that fluorescence probes can be designed to be activatable, that is, only "turned on" under certain conditions. These probes are engineered to emit signal only after binding a target tissue; this design greatly increases sensitivity and specificity in the detection of disease. Current research focuses on two basic types of activatable fluorescence probes. The first developed were conventional enzymatically activatable probes. These fluorescent molecules exist in the quenched state until activated by enzymatic cleavage, which occurs mostly outside of the cells. However, more recently, researchers have begun designing target-cell-specific activatable probes. These fluorophores exist in the quenched state until activated within targeted cells by endolysosomal processing, which results when the probe binds specific receptors on the cell surface and is subsequently internalized. In this Account, we present a review of the rational design and in vivo applications of target-cell-specific activatable probes. In engineering these probes, researchers have asserted control over a variety of factors, including photochemistry, pharmacological profile, and biological properties. Their progress has recently allowed the rational design and synthesis of target-cell-specific activatable fluorescence imaging probes, which can be conjugated to a wide variety of targeting molecules. Several different photochemical mechanisms have been utilized, each of which offers a unique capability for probe design. These include self-quenching, homo- and hetero-fluorescence resonance

A shuttle and space station manipulator system for assembly, docking, maintenance cargo handling and spacecraft retrieval (preliminary design). Volume 1: Management summary

NASA Technical Reports Server (NTRS)

1972-01-01

A preliminary design is established for a general purpose manipulator system which can be used interchangeably on the shuttle and station and can be transferred back and forth between them. Control of the manipulator is accomplished by hard wiring from internal control stations in the shuttle or station. A variety of shuttle and station manipulator operations are considered including servicing the Large Space Telescope; however, emphasis is placed on unloading modules from the shuttle and assembling the space station. Simulation studies on foveal stereoscopic viewing and manipulator supervisory computer control have been accomplished to investigate the feasibility of their use in the manipulator system. The basic manipulator system consists of a single 18.3 m long, 7 degree of freedom (DOF), electrically acutated main boom with an auxiliary 3 DOF electrically actuated, extendible 18.3 m maximum length, lighting, and viewing boom. A 3 DOF orientor assembly is located at the tip of the viewing boom to provide camera pan, tilt, and roll.

Analysis and Design of Crew Sleep Station for ISS

NASA Technical Reports Server (NTRS)

Keener, John F.; Paul, Thomas; Eckhardt, Bradley; Smith, Fredrick

2002-01-01

This paper details the analysis and design of the Temporary Sleep Station (TeSS) environmental control system for International Space Station (ISS). The TeSS will provide crewmembers with a private and personal space, to accommodate sleeping, donning and doffing of clothing, personal communication and performance of recreational activities. The need for privacy to accommodate these activities requires adequate ventilation inside the TeSS. This study considers whether temperature, carbon dioxide, and humidity within the TeSS remain within crew comfort and safety levels for various expected operating scenarios. Evaluation of these scenarios required the use and integration of various simulation codes. An approach was adapted for this study, whereby results from a particular code were integrated with other codes when necessary. Computational Fluid Dynamics (CFD) methods were used to evaluate the flow field inside the TeSS, from which local gradients for temperature, velocity, and species concentration such as CO (sub 2) could be determined. A model of the TeSS, containing a human, as well as equipment such as a laptop computer, was developed in FLUENT, a finite-volume code. Other factors, such as detailed analysis of the heat transfer through the structure, radiation, and air circulation from the TeSS to the US Laboratory Aisle, where the TeSS is housed, were considered in the model. A complementary model was developed in G189A, a code which has been used by NASA/JSC for environmental control systems analyses since the Apollo program. Boundary conditions were exchanged between the FLUENT and G189A TeSS models. G189A provides human respiration rates to the FLUENT model, while the FLUENT model provides local convective heat transfer coefficients to G189A model. An additional benefit from using an approach with both a systems simulation and CFD model, is the capability to verify the results of each model by comparison to the results of the other model. The G189A and

Design for an integrated discipline operations control center for Space Station Freedom

NASA Technical Reports Server (NTRS)

Haines, Richard F.

1993-01-01

This paper presents selected features of a human factors oriented plan for a Space Station Freedom (SSF) ground Discipline Operations Center (DOC) that is integrated with other work areas used by multidisciplinary life scientists. This combined facility is referred to as an integrated DOC or IDOC. This plan is based upon the assumption that there will be a constantly changing array of specialized equipment and procedures used by life sciences principal investigators (PI) on the ground which must be linked to SSF through various DOC systems. Other sites will also be able to communicate with SSF (Anon., 1992). It is also assumed that cost reduction will be a major design consideration and that one integrated structure will be less expensive to build and operate than two separate ones. Since both the DOC personnel and PIs will need to communicate with the flight crew aboard SSF, the general interconnect architecture of the PIs' communication linkage is considered here. Key human factor design elements of this plan include: a candidate facility layout which accommodates three (3), multipurpose, rapidly reconfigurable work areas (suites) and consequent user traffic flow considerations, a multimedia telecommunications support capability, functional (human) traffic flow, optimized internal illumination and acoustics requirements, selected volumetric and safety requirements, and other architectural design parameters.

Artificial gravity studies and design considerations for Space Station centrifuges

NASA Technical Reports Server (NTRS)

Halstead, T. W.; Brown, A. H.; Fuller, C. A.; Oyama, J.

1984-01-01

The requirements to and capabilities of a Space Station biological facility centrifuge are discussed on the basis of an assessment of the objectives and subjects of future microgravity biological experiments. It is argued that the facility should be capable of both acute and extended chronic exposure of test subjects and biological materials to altered-g loading. In addition, the experimental approaches and equipment for microgravity studies on a Space Station are outlined. Finally, the engineering requirements of such a centrifuge are examined, with consideration of radial gravity gradients, size, and physical access to animals.

International interface design for Space Station Freedom - Challenges and solutions

NASA Technical Reports Server (NTRS)

Mayo, Richard E.; Bolton, Gordon R.; Laurini, Daniele

1988-01-01

The definition of interfaces for the International Space Station is discussed, with a focus on negotiations between NASA and ESA. The program organization and division of responsibilities for the Space Station are outlined; the basic features of physical and functional interfaces are described; and particular attention is given to the interface management and documentation procedures, architectural control elements, interface implementation and verification, and examples of Columbus interface solutions (including mechanical, ECLSS, thermal-control, electrical, data-management, standardized user, and software interfaces). Diagrams, drawings, graphs, and tables listing interface types are provided.

Conceptual design and evaluation of selected Space Station concepts, volume 1

NASA Technical Reports Server (NTRS)

1983-01-01

Space Station configuration concepts are defined to meet the NASA Headquarters Concept Development Group (CDG) requirements. Engineering and programmatic data are produced on these concepts suitable for NASA and industry dissemination. A data base is developed for input to the CDG's evaluation of generic Space Station configurations and for use in the critique of the CDG's generic configuration evaluation process.

A systems approach for designing a radio station layout for the U.S. National Airspace

NASA Astrophysics Data System (ADS)

Boci, Erton S.

Today's National Airspace System (NAS) is managed using an aging surveillance radar system. Current radar technology is not adequate to sustain the rapid growth of the commercial, civil, and federal aviation sectors and cannot be adapted to use emerging 21st century airspace surveillance technologies. With 87,000 flights to manage per day, America's ground based radar system has hit a growth ceiling. Consequently, the FAA has embarked on a broad-reaching effort called the Next Generation Air Transportation System (NextGen) that seeks to transform today's aviation airspace management and ensure increased safety and capacity in our NAS. This dissertation presents a systems approach to Service Volume (SV) engineering, a relatively new field of engineering that has emerged in support of the FAA's Automatic Dependent Surveillance -- Broadcast (ADS-B) Air Traffic Modernization Program. SV Engineering is responsible for radio station layout design that would provide the required radio frequency (RF) coverage over a set of Service Volumes, each which represents a section of controlled airspace that is served by a particular air control facility or service. The radio station layout must be optimized to meet system performance, safety, and interference requirements while minimizing the number of radio station sites required to provide RF coverage of the entire airspace of the Unites States. The interference level requirements at the victim (of interference) receivers are the most important and stringent requirements imposed on the ADS-B radio station layout and configuration. In this dissertation, we show a novel and practical way to achieve this optimality by developing and employing several key techniques such as such as reverse radio line-of-site (RLOS) and complex entity-relationship modeling, to address the greater challenges of engineering this complex system. Given that numerous NAS radar facilities are clustered together in relative close proximity to each other, we

Locations of Sampling Stations for Water Quality Monitoring in Water Distribution Networks.

PubMed

Rathi, Shweta; Gupta, Rajesh

2014-04-01

Water quality is required to be monitored in the water distribution networks (WDNs) at salient locations to assure the safe quality of water supplied to the consumers. Such monitoring stations (MSs) provide warning against any accidental contaminations. Various objectives like demand coverage, time for detection, volume of water contaminated before detection, extent of contamination, expected population affected prior to detection, detection likelihood and others, have been independently or jointly considered in determining optimal number and location of MSs in WDNs. "Demand coverage" defined as the percentage of network demand monitored by a particular monitoring station is a simple measure to locate MSs. Several methods based on formulation of coverage matrix using pre-specified coverage criteria and optimization have been suggested. Coverage criteria is defined as some minimum percentage of total flow received at the monitoring stations that passed through any upstream node included then as covered node of the monitoring station. Number of monitoring stations increases with the increase in the value of coverage criteria. Thus, the design of monitoring station becomes subjective. A simple methodology is proposed herein which priority wise iteratively selects MSs to achieve targeted demand coverage. The proposed methodology provided the same number and location of MSs for illustrative network as an optimization method did. Further, the proposed method is simple and avoids subjectivity that could arise from the consideration of coverage criteria. The application of methodology is also shown on a WDN of Dharampeth zone (Nagpur city WDN in Maharashtra, India) having 285 nodes and 367 pipes.

Designing Multi-target Compound Libraries with Gaussian Process Models.

PubMed

Bieler, Michael; Reutlinger, Michael; Rodrigues, Tiago; Schneider, Petra; Kriegl, Jan M; Schneider, Gisbert

2016-05-01

We present the application of machine learning models to selecting G protein-coupled receptor (GPCR)-focused compound libraries. The library design process was realized by ant colony optimization. A proprietary Boehringer-Ingelheim reference set consisting of 3519 compounds tested in dose-response assays at 11 GPCR targets served as training data for machine learning and activity prediction. We compared the usability of the proprietary data with a public data set from ChEMBL. Gaussian process models were trained to prioritize compounds from a virtual combinatorial library. We obtained meaningful models for three of the targets (5-HT2c , MCH, A1), which were experimentally confirmed for 12 of 15 selected and synthesized or purchased compounds. Overall, the models trained on the public data predicted the observed assay results more accurately. The results of this study motivate the use of Gaussian process regression on public data for virtual screening and target-focused compound library design. © 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

International Space Station Alpha (ISSA) Integrated Traffic Model

NASA Technical Reports Server (NTRS)

Gates, R. E.

1995-01-01

The paper discusses the development process of the International Space Station Alpha (ISSA) Integrated Traffic Model which is a subsystem analyses tool utilized in the ISSA design analysis cycles. Fast-track prototyping of the detailed relationships between daily crew and station consumables, propellant needs, maintenance requirements and crew rotation via spread sheets provide adequate benchmarks to assess cargo vehicle design and performance characteristics.

Work continues on Leonardo, the Multi-Purpose Logistics Module, in the Space Station Processing Faci

NASA Technical Reports Server (NTRS)

1999-01-01

Workers in the Space Station Processing Facility work on Leonardo, the Multipurpose Logistics Module (MPLM) built by the Agenzia Spaziale Italiana (ASI). The MPLM, a reusable logistics carrier, will be the primary delivery system used to resupply and return International Space Station cargo requiring a pressurized environment. Leonardo is the first of three MPLM carriers for the International Space Station. It is scheduled to be launched on Space Shuttle Mission STS-102, targeted for June 2000. Leonardo shares space in the SSPF with the Shuttle Radar Topography Mission (SRTM), targeted for launch in September 1999, and Destiny, the U.S. Lab module, targeted for mission STS-98 in late April 2000.

Rational design of chemical genetic probes of RNA function and lead therapeutics targeting repeating transcripts.

PubMed

Disney, Matthew D

2013-12-01

RNA is an important yet vastly underexploited target for small molecule chemical probes or lead therapeutics. Small molecules have been used successfully to modulate the function of the bacterial ribosome, viral RNAs and riboswitches. These RNAs are either highly expressed or can be targeted using substrate mimicry, a mainstay in the design of enzyme inhibitors. However, most cellular RNAs are neither highly expressed nor have a lead small molecule inhibitor, a significant challenge for drug discovery efforts. Herein, I describe the design of small molecules targeting expanded repeating transcripts that cause myotonic muscular dystrophy (DM). These test cases illustrate the challenges of designing small molecules that target RNA and the advantages of targeting repeating transcripts. Lastly, I discuss how small molecules might be more advantageous than oligonucleotides for targeting RNA. Copyright © 2013 Elsevier Ltd. All rights reserved.

The Design and Application of Data Storage System in Miyun Satellite Ground Station

NASA Astrophysics Data System (ADS)

Xue, Xiping; Su, Yan; Zhang, Hongbo; Liu, Bin; Yao, Meijuan; Zhao, Shu

2015-04-01

China has launched Chang'E-3 satellite in 2013, firstly achieved soft landing on moon for China's lunar probe. Miyun satellite ground station firstly used SAN storage network system based-on Stornext sharing software in Chang'E-3 mission. System performance fully meets the application requirements of Miyun ground station data storage.The Stornext file system is a sharing file system with high performance, supports multiple servers to access the file system using different operating system at the same time, and supports access to data on a variety of topologies, such as SAN and LAN. Stornext focused on data protection and big data management. It is announced that Quantum province has sold more than 70,000 licenses of Stornext file system worldwide, and its customer base is growing, which marks its leading position in the big data management.The responsibilities of Miyun satellite ground station are the reception of Chang'E-3 satellite downlink data and management of local data storage. The station mainly completes exploration mission management, receiving and management of observation data, and provides a comprehensive, centralized monitoring and control functions on data receiving equipment. The ground station applied SAN storage network system based on Stornext shared software for receiving and managing data reliable.The computer system in Miyun ground station is composed by business running servers, application workstations and other storage equipments. So storage systems need a shared file system which supports heterogeneous multi-operating system. In practical applications, 10 nodes simultaneously write data to the file system through 16 channels, and the maximum data transfer rate of each channel is up to 15MB/s. Thus the network throughput of file system is not less than 240MB/s. At the same time, the maximum capacity of each data file is up to 810GB. The storage system planned requires that 10 nodes simultaneously write data to the file system through 16

Ergonomic Work Station Design to Improve Workload Quality and Productivity of the Craffsmen

NASA Astrophysics Data System (ADS)

Widana, IK; Wayan Sumetri, Ni; Ketut Sutapa, I.

2018-01-01

This study is a research on ergonomics field, especially for ergonomics work station. This research begins with direct observation on the work process of carving craft. In addition to the aspect of occupational health, the stages of the process are also subject matter in the effort to solve the research problem. In accordance with the master plan of research of Bali State Polytechnic, problem solving will be focused on human aspect and utilization of appropriate technology, so that will get the work process ENASEP (effective, convenient, safe, healthy, efficient and productive) Technical easy to work, economical, ergonomic, energy saving, environmentally friendly and in accordance with the trend of the era. The method to be used in this research is experimental with the same subject design. Involves 9 samples who perform activities on conditions before and after treatment. Data on environmental conditions were analyzed by Mann-Whitney test. Data on work productivity and workload were tested with two pair sample t-test at a significance level of 5%. The results showed that by utilizing ergonomic work stations, occupational health indicators such as workload showed better signs, indicated by decreased the workload. In addition to occupational health, productivity indicators also increased significantly.

The international space station as a free flyer servicing node

NASA Astrophysics Data System (ADS)

Antol, Jeffrey; Headley, David E.

1999-01-01

The International Space Station will provide a multitude of opportunities for an expanding customer base to make use of this international resource. One such opportunity is servicing of various visiting vehicles that are in a similar orbit to the station. Servicing may include change-out of payloads, replenishment of consumables, repair, and refurbishment operations. Previous studies have been conducted in which ``paper'' free flyers have been assessed against the station's ability to accommodate them. Over the last several months though, an already flown free flyer, EURECA, was assessed as a real-life visiting free flyer design reference mission. Issues such as capture/berthing, servicing, logistics support, and stowage were assessed for station design and operational approaches. This paper will highlight critical visiting vehicle design considerations, identify station issues, and provide recommendations for accommodation of a wide range of visiting vehicle requirements of the future.

The International Space Station As a Free Flyer Servicing Node

NASA Technical Reports Server (NTRS)

Antol, Jeffrey; Headley, David E.

1999-01-01

The International Space Station will provide a multitude of opportunities for an expanding customer base to make use of this international resource. One such opportunity is servicing of various visiting vehicles that are in a similar orbit to the station. Servicing may include change-out of payloads, replenishment of consumables, repair, and refurbishment operations. Previous studies have been conducted in which "paper" free flyers have been assessed against the station s ability to accommodate them. Over the last several months though, an already flown free flyer, EURECA, was assessed as a real-life visiting free flyer design reference mission. Issues such as capture/berthing, servicing, logistics support, and stowage were assessed for station design and operational approaches. This paper will highlight critical visiting vehicle design considerations, identify station issues, and provide recommendations for accommodation of a wide range of visiting vehicle requirements of the future.

Space station assembly/servicing capabilities

NASA Technical Reports Server (NTRS)

Joyce, Joseph

1986-01-01

The aim is to place a permanently manned space station on-orbit around the Earth, which is international in scope. The program is nearing the close of the system definition and preliminary design phase. The first shuttle launch for space station assembly on-orbit is estimated for January 1993. Topics perceived to be important to on-orbit assembly and servicing are discussed. This presentation is represented by charts.

Mock Target Window OTR and IR Design and Testing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wass, Alexander Joseph

In order to fully verify temperature measurements made on the target window using infrared (IR) optical non-contact methods, actual comparative measurements are made with a real beam distribution as the heat source using Argonne National Laboratory’s (ANL) 35 MeV electron accelerator. Using Monte Carlo N-Particle (MCNP) simulations and thermal Finite Element Analysis (FEA), a cooled mock target window with thermocouple implants is designed to be used in such a test to achieve window temperatures up to 700°C. An uncoated and blackcoated mock window is designed to enhance the IR temperature measurements and verify optical transmitted radiation (OTR) imagery. This allowsmore » us to fully verify and characterize our temperature accuracy with our current IR camera method and any future method we may wish to explore using actual production conditions. This test also provides us with valuable conclusions/concerns regarding the calibration method we developed using our IR test stand at TA-53 in MPF-14.« less

An Earth-Moon Transfer Trajectory Design and Analysis Considering Spacecraft's Visibility from Daejeon Ground Station at TLI and LOI Maneuvers

NASA Astrophysics Data System (ADS)

Woo, Jin; Song, Young-Joo; Park, Sang-Young; Kim, Hae-Dong; Sim, Eun-Sup

2010-09-01

The optimal Earth-Moon transfer trajectory considering spacecraft's visibility from the Daejeon ground station visibility at both the trans lunar injection (TLI) and lunar orbit insertion (LOI) maneuvers is designed. Both the TLI and LOI maneuvers are assumed to be impulsive thrust. As the successful execution of the TLI and LOI maneuvers are crucial factors among the various lunar mission parameters, it is necessary to design an optimal lunar transfer trajectory which guarantees the visibility from a specified ground station while executing these maneuvers. The optimal Earth-Moon transfer trajectory is simulated by modifying the Korean Lunar Mission Design Software using Impulsive high Thrust Engine (KLMDS-ITE) which is developed in previous studies. Four different mission scenarios are established and simulated to analyze the effects of the spacecraft's visibility considerations at the TLI and LOI maneuvers. As a result, it is found that the optimal Earth-Moon transfer trajectory, guaranteeing the spacecraft's visibility from Daejeon ground station at both the TLI and LOI maneuvers, can be designed with slight changes in total amount of delta-Vs. About 1% difference is observed with the optimal trajectory when none of the visibility condition is guaranteed, and about 0.04% with the visibility condition is only guaranteed at the time of TLI maneuver. The spacecraft's mass which can delivered to the Moon, when both visibility conditions are secured is shown to be about 534 kg with assumptions of KSLV-2's on-orbit mass about 2.6 tons. To minimize total mission delta-Vs, it is strongly recommended that visibility conditions at both the TLI and LOI maneuvers should be simultaneously implemented to the trajectory optimization algorithm.

Designing Targeted Educational Voucher Schemes for the Poor in Developing Countries

ERIC Educational Resources Information Center

Shafiq, M. Najeeb

2009-01-01

Targeted educational voucher schemes [TEVS] are often proposed for poor children in developing countries. This article explores the design of an effective TEVS using three policy instruments: regulation, support services, and finance. The regulation design addresses the rules that must be adhered to by participating households, children, and…

Space station needs, attributes and architectural options: Study summary

NASA Technical Reports Server (NTRS)

1983-01-01

Space station needs, attributes, and architectural options that affect the future implementation and design of a space station system are examined. Requirements for candidate missions are used to define functional attributes of a space station. Station elements that perform these functions form the basic station architecture. Alternative ways to accomplish these functions are defined and configuration concepts are developed and evaluated. Configuration analyses are carried to the point that budgetary cost estimates of alternate approaches could be made. Emphasis is placed on differential costs for station support elements and benefits that accrue through use of the station.

International Space Station Alpha (ISSA) Integrated Traffic Model

NASA Technical Reports Server (NTRS)

Gates, Robert E.

1994-01-01

The paper discusses the development process of the International Space Station Alpha (ISSA) Integrated Traffic Model which is a subsystem analyses tool utilized in the ISSA design analysis cycles. Fast-track prototyping of the detailed relationships between daily crew and station consumables, propellant needs, maintenance requirements, and crew rotation via spread sheets provides adequate bench marks to assess cargo vehicle design and performance characteristics.

An analytical investigation of a conceptual design for the station transverse boom rotary joint structure

NASA Technical Reports Server (NTRS)

Lake, M. S.; Bush, H. G.

1986-01-01

A study was conducted to define an annular ring, discrete roller assembly concept for the space station transverse boom rotary joint. The concept was analyzed using closed-form and finite element techniques, to size structural members for a range of joint diameters and to determine necessary equivalent stiffnesses for the roller assemblies. Also, a mass study of the system was conducted to determine its practicality, and maximum loads in the joint were identified. To obtain the optimum balance between high stiffness and low structural mass in the design of the rotary joint, it is necessary to maximize the diameter of the annular ring within operational constraints (i.e., shuttle cargo bay size). Further, a rotary joint designed with the largest possible ring diameter will result in minimum operational loads in both the roller assemblies and the transition truss members while also allowing minimum design stiffnesses for the roller assemblies.

International Space Station (ISS)

NASA Image and Video Library

1998-11-01

This photograph shows the U.S. Laboratory Module (also called Destiny) for the International Space Station (ISS), in the Space Station manufacturing facility at the Marshall Space Flight Center, being readied for shipment to the Kennedy Space Center. The U.S. Laboratory module is the centerpiece of the ISS, where science experiments will be performed in the near-zero gravity of space. The Destiny Module was launched aboard the Space Shuttle orbiter Atlantis (STS-67 mission) on February 7, 2001. The aluminum module is 8.5 meters (28 feet) long and 4.3 meters (14 feet) in diameter. The laboratory consists of three cylindrical sections and two endcones with hatches that will be mated to other station components. A 50.9-centimeter- (20-inch-) diameter window is located on one side of the center module segment. This pressurized module is designed to accommodate pressurized payloads. It has a capacity of 24 rack locations, and payload racks will occupy 13 locations especially designed to support experiments. The ISS is a multidisciplinary laboratory, technology test bed, and observatory that will provide unprecedented undertakings in scientific, technological, and international experimentation.

International Space Station (ISS)

NASA Image and Video Library

1997-01-01

In this photograph, the U.S. Laboratory Module (also called Destiny) for the International Space Station (ISS) is shown under construction in the West High Bay of the Space Station manufacturing facility (building 4708) at the Marshall Space Flight Center. The U.S. Laboratory module is the centerpiece of the ISS, where science experiments will be performed in the near-zero gravity of space. The Destiny Module was launched aboard the Space Shuttle orbiter Atlantis (STS-98 mission) on February 7, 2001. The aluminum module is 8.5 meters (28 feet) long and 4.3 meters (14 feet) in diameter. The laboratory consists of three cylindrical sections and two endcones with hatches that will be mated to other station components. A 50.9-centimeter- (20-inch-) diameter window is located on one side of the center module segment. This pressurized module is designed to accommodate pressurized payloads. It has a capacity of 24 rack locations, and payload racks will occupy 13 locations especially designed to support experiments. The ISS is a multidisciplinary laboratory, technology test bed, and observatory that will provide unprecedented undertakings in scientific, technological, and international experimentation.

International Space Station (ISS)

NASA Image and Video Library

1997-11-01

In this photograph, the U.S. Laboratory Module (also called Destiny) for the International Space Station (ISS) is shown under construction in the West High Bay of the Space Station manufacturing facility (building 4708) at the Marshall Space Flight Center. The U.S. Laboratory module is the centerpiece of the ISS, where science experiments will be performed in the near-zero gravity of space. The Destiny Module was launched aboard the Space Shuttle orbiter Atlantis (STS-98 mission) on February 7, 2001. The aluminum module is 8.5 meters (28 feet) long and 4.3 meters (14 feet) in diameter. The laboratory consists of three cylindrical sections and two endcones with hatches that will be mated to other station components. A 50.9-centimeter- (20-inch-) diameter window is located on one side of the center module segment. This pressurized module is designed to accommodate pressurized payloads. It has a capacity of 24 rack locations, and payload racks will occupy 13 locations especially designed to support experiments. The ISS is a multidisciplinary laboratory, technology test bed, and observatory that will provide unprecedented undertakings in scientific, technological, and international experimentation.

International Space Station (ISS)

NASA Image and Video Library

2000-02-01

A section of the International Space Station truss assembly arrived at the Marshall Space Flight Center on NASA's Super Guppy cargo plane for structural and design testing as well as installation of critical flight hardware.

Design of an ignition target for the laser megajoule, mitigating parametric instabilities

NASA Astrophysics Data System (ADS)

Laffite, S.; Loiseau, P.

2010-10-01

Laser plasma interaction (LPI) is a critical issue in ignition target design. Based on both scaling laws and two-dimensional calculations, this article describes how we can constrain a laser megajoule (LMJ) [J. Ebrardt and J. M. Chaput, J. Phys.: Conf. Ser. 112, 032005 (2008)] target design by mitigating LPI. An ignition indirect drive target has been designed for the 2/3 LMJ step. It requires 0.9 MJ and 260 TW of laser energy and power, to achieve a temperature of 300 eV in a rugby-shaped Hohlraum and give a yield of about 20 MJ. The study focuses on the analysis of linear gain for stimulated Raman and Brillouin scatterings. Enlarging the focal spot is an obvious way to reduce linear gains. We show that this reduction is nonlinear with the focal spot size. For relatively small focal spot area, linear gains are significantly reduced by enlarging the focal spot. However, there is no benefit in too large focal spots because of necessary larger laser entrance holes, which require more laser energy. Furthermore, this leads to the existence, for a given design, of a minimum value for linear gains for which we cannot go below.

Lunar base mission technology issues and orbital demonstration requirements on space station

NASA Technical Reports Server (NTRS)

Llewellyn, Charles P.; Weidman, Deene J.

1992-01-01

The International Space Station has been the object of considerable design, redesign, and alteration since it was originally proposed in early 1984. In the intervening years the station has slowly evolved to a specific design that was thoroughly reviewed by a large agency-wide Critical Evaluation Task Force (CETF). As space station designs continue to evolve, studies must be conducted to determine the suitability of the current design for some of the primary purposes for which the station will be used. This paper concentrates on the technology requirements and issues, the on-orbit demonstration and verification program, and the space station focused support required prior to the establishment of a permanently manned lunar base as identified in the National Commission on Space report. Technology issues associated with the on-orbit assembly and processing of the lunar vehicle flight elements are also discussed.

Vision requirements for Space Station applications

NASA Technical Reports Server (NTRS)

Crouse, K. R.

1985-01-01

Problems which will be encountered by computer vision systems in Space Station operations are discussed, along with solutions be examined at Johnson Space Station. Lighting cannot be controlled in space, nor can the random presence of reflective surfaces. Task-oriented capabilities are to include docking to moving objects, identification of unexpected objects during autonomous flights to different orbits, and diagnoses of damage and repair requirements for autonomous Space Station inspection robots. The approaches being examined to provide these and other capabilities are television IR sensors, advanced pattern recognition programs feeding on data from laser probes, laser radar for robot eyesight and arrays of SMART sensors for automated location and tracking of target objects. Attention is also being given to liquid crystal light valves for optical processing of images for comparisons with on-board electronic libraries of images.

A Mars Micro-Meteorological Station Mission

NASA Technical Reports Server (NTRS)

Merrihew, Steven C.; Haberle, Robert; Lemke, Lawrence G.

1995-01-01

The Mars Micro-Meteorological Station (Micro-Met) Mission is designed to provide the global surface pressure measurements required to help characterize the martian general circulation and climate system. Measurements of surface pressure distributed both spatially and temporally, coupled with simultaneous measurements from orbit, will enable the determination of the general circulation, structure and driving factors of the martian atmosphere as well as the seasonal CO2 cycle. The influence of these atmospheric factors will in turn provide insight into the overall martian climate system. With the science objective defined as the long term (at least one Mars year) globally distributed measurement of surface atmospheric pressure, a straightforward, near term and low cost network mission has been designed. The Micro-Met mission utilizes a unique silicon micro-machined pressure sensor coupled with a robust and lightweight surface station to deliver to Mars 16 Micro-Met stations via a Med-Lite launch vehicle. The battery powered Micro-Met surface stations are designed to autonomously measure, record and transmit the science data via a UHF relay satellite. Entry, descent and landing is provided by an aeroshell with a new lightweight ceramic thermal protection system, a parachute and an impact absorbing structure. The robust lander is capable of surviving the landing loads imposed by the high altitude landing sites required in a global network. By trading the ability to make many measurements at a single site for the ability to make a single measurement at several sites, the Micro-Met mission design satisfies the requirement for truly global meteorological science.

Design of a remotely piloted vehicle for a low Reynolds number station keeping mission

NASA Technical Reports Server (NTRS)

1990-01-01

Six teams of senior level Aerospace Engineering undergraduates were given a request for proposal, asking for a design concept for a remotely piloted vehicle (RPV). This RPV was to be designed to fly at a target Reynolds number of 1 times 10(exp 5). The craft was to maximize loiter time and perform an indoor, closed course flight. As part of the proposal, each team was required to construct a prototype and validate their design with a flight demonstration.

Mars mission effects on Space Station evolution

NASA Technical Reports Server (NTRS)

Askins, Barbara S.; Cook, Stephen G.

1989-01-01

The permanently manned Space Station scheduled to be operational in low earth by the mid 1990's, will provide accommodations for science, applications, technology, and commercial users, and will develop enabling capabilities for future missions. A major aspect of the baseline Space Station design is that provisions for evolution to greater capabilities are included in the systems and subsystems designs. User requirements are the basis for conceptual evolution modes or infrastructure to support the paths. Four such modes are discussed in support of a Human to Mars mission, along with some of the near term actions protecting the future of supporting Mars missions on the Space Station. The evolution modes include crew and payload transfer, storage, checkout, assembly, maintenance, repair, and fueling.

Assessing the acoustical climate of underground stations.

PubMed

Nowicka, Elzbieta

2007-01-01

Designing a proper acoustical environment--indispensable to speech recognition--in long enclosures is difficult. Although there is some literature on the acoustical conditions in underground stations, there is still little information about methods that make estimation of correct reverberation conditions possible. This paper discusses the assessment of the reverberation conditions of underground stations. A comparison of the measurements of reverberation time in Warsaw's underground stations with calculated data proves there are divergences between measured and calculated early decay time values, especially for long source-receiver distances. Rapid speech transmission index values for measured stations are also presented.

Space Station Furnace Facility Core. Requirements definition and conceptual design study. Volume 2: Technical report. Appendix 6: Technical summary reports

NASA Technical Reports Server (NTRS)

1992-01-01

The Space Station Furnace Facility (SSFF) is a modular facility for materials research in the microgravity environment of the Space Station Freedom (SSF). The SSFF is designed for crystal growth and solidification research in the fields of electronic and photonic materials, metals and alloys, and glasses and ceramics and will allow for experimental determination of the role of gravitational forces in the solidification process. The facility will provide a capability for basic scientific research and will evaluate the commercial viability of low-gravity processing of selected technologically important materials. The facility is designed to support a complement of furnace modules as outlined in the Science Capabilities Requirements Document (SCRD). The SSFF is a three rack facility that provides the functions, interfaces, and equipment necessary for the processing of the furnaces and consists of two main parts: the SSFF Core Rack and the two Experiment Racks. The facility is designed to accommodate two experimenter-provided furnace modules housed within the two experiment racks, and is designed to operate these two furnace modules simultaneously. The SCRD specifies a wide range of furnace requirements and serves as the basis for the SSFF conceptual design. SSFF will support automated processing during the man-tended operations and is also designed for crew interface during the permanently manned configuration. The facility is modular in design and facilitates changes as required, so the SSFF is adept to modifications, maintenance, reconfiguration, and technology evolution.

CFD Analysis and Design of Detailed Target Configurations for an Accelerator-Driven Subcritical System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kraus, Adam; Merzari, Elia; Sofu, Tanju

2016-08-01

High-fidelity analysis has been utilized in the design of beam target options for an accelerator driven subcritical system. Designs featuring stacks of plates with square cross section have been investigated for both tungsten and uranium target materials. The presented work includes the first thermal-hydraulic simulations of the full, detailed target geometry. The innovative target cooling manifold design features many regions with complex flow features, including 90 bends and merging jets, which necessitate three-dimensional fluid simulations. These were performed using the commercial computational fluid dynamics code STAR-CCM+. Conjugate heat transfer was modeled between the plates, cladding, manifold structure, and fluid. Steady-statemore » simulations were performed but lacked good residual convergence. Unsteady simulations were then performed, which converged well and demonstrated that flow instability existed in the lower portion of the manifold. It was established that the flow instability had little effect on the peak plate temperatures, which were well below the melting point. The estimated plate surface temperatures and target region pressure were shown to provide sufficient margin to subcooled boiling for standard operating conditions. This demonstrated the safety of both potential target configurations during normal operation.« less

Conformational stability as a design target to control protein aggregation.

PubMed

Costanzo, Joseph A; O'Brien, Christopher J; Tiller, Kathryn; Tamargo, Erin; Robinson, Anne Skaja; Roberts, Christopher J; Fernandez, Erik J

2014-05-01

Non-native protein aggregation is a prevalent problem occurring in many biotechnological manufacturing processes and can compromise the biological activity of the target molecule or induce an undesired immune response. Additionally, some non-native aggregation mechanisms lead to amyloid fibril formation, which can be associated with debilitating diseases. For natively folded proteins, partial or complete unfolding is often required to populate aggregation-prone conformational states, and therefore one proposed strategy to mitigate aggregation is to increase the free energy for unfolding (ΔGunf) prior to aggregation. A computational design approach was tested using human γD crystallin (γD-crys) as a model multi-domain protein. Two mutational strategies were tested for their ability to reduce/increase aggregation rates by increasing/decreasing ΔGunf: stabilizing the less stable domain and stabilizing the domain-domain interface. The computational protein design algorithm, RosettaDesign, was implemented to identify point variants. The results showed that although the predicted free energies were only weakly correlated with the experimental ΔGunf values, increased/decreased aggregation rates for γD-crys correlated reasonably well with decreases/increases in experimental ΔGunf, illustrating improved conformational stability as a possible design target to mitigate aggregation. However, the results also illustrate that conformational stability is not the sole design factor controlling aggregation rates of natively folded proteins.

An autodissemination station for the transfer of an insect growth regulator to mosquito oviposition sites.

PubMed

Gaugler, R; Suman, D; Wang, Y

2012-03-01

A prototype autodissemination station to topically contaminate oviposition-seeking container-dwelling mosquitoes with the insect growth regulator, pyriproxyfen, was developed and tested in the laboratory. Our test subject was the Asian tiger mosquito, Aedes albopictus (Skuse) (Diptera: Culicidae), an urban species that colonizes small-volume cryptic larval habitats and is a skip ovipositor that visits multiple containers. The station consists of a water reservoir to attract gravid females, which is joined to a transfer chamber designed to contaminate visiting mosquitoes. The unit is easily constructed by moulding wet shredded cardboard using corn starch as a binder. The essential criteria that must be met to prove the efficacy of an autodissemination station require it to demonstrate effectiveness in attracting the target insect, in transferring the toxicant to the insect that will disperse the agent, and in facilitating the subsequent transfer of the toxicant from the insect to target habitats at a lethal concentration. Cage experiments demonstrated that the unit was readily accepted by gravid females as an oviposition site. A powder formulation of pyriproxyfen-impregnated silica particles adhered to visiting Ae. albopictus females (mean: 66 particles/female), although particles were lost over time. In cage (2.2 m(3) ) trials, pyriproxyfen-charged stations resulted in 100% inhibition of adult emergence, whereas in small-room (31.1 m(3) ) trials, 81% emergence inhibition was recorded. The venereal transfer of pyriproxyfen from contaminated males to virgin females was also observed, and pyriproxyfen was subsequently transferred to water-holding containers at concentrations that inhibited emergence. Key autodissemination station features include lack of maintenance requirements, biodegradable construction, low cost and low risk. © 2011 The Authors. Medical and Veterinary Entomology © 2011 The Royal Entomological Society.

Design specification for the European Spallation Source neutron generating target element

NASA Astrophysics Data System (ADS)

Aguilar, A.; Sordo, F.; Mora, T.; Mena, L.; Mancisidor, M.; Aguilar, J.; Bakedano, G.; Herranz, I.; Luna, P.; Magan, M.; Vivanco, R.; Jimenez-Villacorta, F.; Sjogreen, K.; Oden, U.; Perlado, J. M.; Martinez, J. L.; Bermejo, F. J.

2017-06-01

The paper addresses some of the most relevant issues concerning the thermal hydraulics and radiation damage of the neutron generation target to be built at the European Spallation Source as recently approved after a critical design review. The target unit consists of a set of Tungsten blocks placed inside a wheel of 2.5 m diameter which rotates at some 0.5 Hz in order to distribute the heat generated from incoming protons which reach the target in the radial direction. The spallation material elements are composed of an array of Tungsten pieces which rest on a rotating steel support (the cassette) and are distributed in a cross-flow configuration. The thermal, mechanical and radiation effects resulting from the impact of a 2 GeV proton pulse are analysed in detail as well as an evaluation of the inventory of spallation products. The current design is found to conform to specifications and found to be robust enough to deal with several accident scenarios.

47 CFR 73.27 - Local channels; Class C stations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false Local channels; Class C stations. 73.27 Section... BROADCAST SERVICES AM Broadcast Stations § 73.27 Local channels; Class C stations. Within the conterminous 48 states, the following frequencies are designated as local channels, and are assigned for use by...

47 CFR 97.213 - Telecommand of an amateur station.

Code of Federal Regulations, 2011 CFR

2011-10-01

... telephone number of the station licensee and at least one designated control operator is posted in a... 47 Telecommunication 5 2011-10-01 2011-10-01 false Telecommand of an amateur station. 97.213... SERVICES AMATEUR RADIO SERVICE Special Operations § 97.213 Telecommand of an amateur station. An amateur...

47 CFR 97.213 - Telecommand of an amateur station.

Code of Federal Regulations, 2010 CFR

2010-10-01

... telephone number of the station licensee and at least one designated control operator is posted in a... 47 Telecommunication 5 2010-10-01 2010-10-01 false Telecommand of an amateur station. 97.213... SERVICES AMATEUR RADIO SERVICE Special Operations § 97.213 Telecommand of an amateur station. An amateur...

47 CFR 97.213 - Telecommand of an amateur station.

Code of Federal Regulations, 2014 CFR

2014-10-01

... telephone number of the station licensee and at least one designated control operator is posted in a... 47 Telecommunication 5 2014-10-01 2014-10-01 false Telecommand of an amateur station. 97.213... SERVICES AMATEUR RADIO SERVICE Special Operations § 97.213 Telecommand of an amateur station. An amateur...

47 CFR 97.213 - Telecommand of an amateur station.

Code of Federal Regulations, 2013 CFR

2013-10-01

... telephone number of the station licensee and at least one designated control operator is posted in a... 47 Telecommunication 5 2013-10-01 2013-10-01 false Telecommand of an amateur station. 97.213... SERVICES AMATEUR RADIO SERVICE Special Operations § 97.213 Telecommand of an amateur station. An amateur...

47 CFR 97.213 - Telecommand of an amateur station.

Code of Federal Regulations, 2012 CFR

2012-10-01

... telephone number of the station licensee and at least one designated control operator is posted in a... 47 Telecommunication 5 2012-10-01 2012-10-01 false Telecommand of an amateur station. 97.213... SERVICES AMATEUR RADIO SERVICE Special Operations § 97.213 Telecommand of an amateur station. An amateur...

Historical annotated bibliography: Space Station documents

NASA Technical Reports Server (NTRS)

Whalen, Jessie E. (Compiler); Mckinley, Sarah L. (Compiler); Gates, Thomas G. (Compiler)

1988-01-01

Information is presented regarding documentation which has been produced in the Space Station program. This information will enable the researcher to locate readily documents pertinent to a particular study. It is designed to give the historian the necessary data from which to compile the written histories and to preserve records of historically significant aspects of Marshall's involvement in Space Shuttle and Space Station.

Workstations and gloveboxes for space station

NASA Technical Reports Server (NTRS)

Junge, Maria

1990-01-01

Lockheed Missiles and Space Company is responsible for designing, developing, and building the Life Sciences Glovebox, the Laboratory Sciences Workbench, and the Maintenance Workstation plus 16 other pieces of equipment for the U.S. Laboratory Module of the Space Station Freedom. The Laboratory Sciences Workbench and the Maintenance Workstation were functionally combined into a double structure to save weight and volume which are important commodities on the Space Station Freedom. The total volume of these items is approximately 180 cubic feet. These workstations and the glovebox will be delivered to NASA in 1994 and will be launched in 1995. The very long lifetime of 30 years presents numerous technical challenges in the areas of design and reliability. The equipment must be easy to use by international crew members and also easy to maintain on-orbit. For example, seals must be capable of on-orbit changeout and reverification. The stringent contamination requirements established for Space Station Freedom equipment also complicate the zero gravity glovebox design. The current contamination control system for the Life Sciences Glovebox and the Maintenance Workstation is presented. The requirement for the Life Sciences Glovebox to safely contain toxic, reactive, and radioactive materials presents challenges. Trade studies, CAD simulation techniques and design challenges are discussed to illustrate the current baseline conceptual designs. Areas which need input from the user community are identified.

The Space Station integrated refuse management system

NASA Technical Reports Server (NTRS)

1988-01-01

The University of Central Florida's design of an Integrated Refuse Management System for the proposed International Space Station is addressed. Four integratable subsystems capable of handling an estimated Orbiter shortfall of nearly 40,000 lbs of refuse produced annually are discussed. The subsystems investigated were: (1) collection and transfer; (2) recycle and reuse; (3) advanced disposal; and (4) propulsion assist in disposal. Emphasis is placed on the recycling or reuse of those materials ultimately providing a source of Space Station refuse. Special consideration is given to various disposal methods capable of completely removing refuse from close proximity of the Space Station. There is evidence that pyrolysis is the optimal solution for disposal of refuse through employment of a Rocket Jettison Vehicle. Additionally, design considerations and specifications of the Refuse Management System are discussed. Optimal and alternate design solutions for each of the four subsystems are summarized. Finally, the system configuration is described and reviewed.

Space station Simulation Computer System (SCS) study for NASA/MSFC. Volume 3: Refined conceptual design report

NASA Technical Reports Server (NTRS)

1989-01-01

The results of the refined conceptual design phase (task 5) of the Simulation Computer System (SCS) study are reported. The SCS is the computational portion of the Payload Training Complex (PTC) providing simulation based training on payload operations of the Space Station Freedom (SSF). In task 4 of the SCS study, the range of architectures suitable for the SCS was explored. Identified system architectures, along with their relative advantages and disadvantages for SCS, were presented in the Conceptual Design Report. Six integrated designs-combining the most promising features from the architectural formulations-were additionally identified in the report. The six integrated designs were evaluated further to distinguish the more viable designs to be refined as conceptual designs. The three designs that were selected represent distinct approaches to achieving a capable and cost effective SCS configuration for the PTC. Here, the results of task 4 (input to this task) are briefly reviewed. Then, prior to describing individual conceptual designs, the PTC facility configuration and the SSF systems architecture that must be supported by the SCS are reviewed. Next, basic features of SCS implementation that have been incorporated into all selected SCS designs are considered. The details of the individual SCS designs are then presented before making a final comparison of the three designs.

Design of nuclease-based target recycling signal amplification in aptasensors.

PubMed

Yan, Mengmeng; Bai, Wenhui; Zhu, Chao; Huang, Yafei; Yan, Jiao; Chen, Ailiang

2016-03-15

Compared with conventional antibody-based immunoassay methods, aptasensors based on nucleic acid aptamer have made at least two significant breakthroughs. One is that aptamers are more easily used for developing various simple and rapid homogeneous detection methods by "sample in signal out" without multi-step washing. The other is that aptamers are more easily employed for developing highly sensitive detection methods by using various nucleic acid-based signal amplification approaches. As many substances playing regulatory roles in physiology or pathology exist at an extremely low concentration and many chemical contaminants occur in trace amounts in food or environment, aptasensors for signal amplification contribute greatly to detection of such targets. Among the signal amplification approaches in highly sensitive aptasensors, the nuclease-based target recycling signal amplification has recently become a research focus because it shows easy design, simple operation, and rapid reaction and can be easily developed for homogenous assay. In this review, we summarized recent advances in the development of various nuclease-based target recycling signal amplification with the aim to provide a general guide for the design of aptamer-based ultrasensitive biosensing assays. Copyright © 2015 Elsevier B.V. All rights reserved.

Design challenges in nanoparticle-based platforms: Implications for targeted drug delivery systems

NASA Astrophysics Data System (ADS)

Mullen, Douglas Gurnett

Characterization and control of heterogeneous distributions of nanoparticle-ligand components are major design challenges for nanoparticle-based platforms. This dissertation begins with an examination of poly(amidoamine) (PAMAM) dendrimer-based targeted delivery platform. A folic acid targeted modular platform was developed to target human epithelial cancer cells. Although active targeting was observed in vitro, active targeting was not found in vivo using a mouse tumor model. A major flaw of this platform design was that it did not provide for characterization or control of the component distribution. Motivated by the problems experienced with the modular design, the actual composition of nanoparticle-ligand distributions were examined using a model dendrimer-ligand system. High Pressure Liquid Chromatography (HPLC) resolved the distribution of components in samples with mean ligand/dendrimer ratios ranging from 0.4 to 13. A peak fitting analysis enabled the quantification of the component distribution. Quantified distributions were found to be significantly more heterogeneous than commonly expected and standard analytical parameters, namely the mean ligand/nanoparticle ratio, failed to adequately represent the component heterogeneity. The distribution of components was also found to be sensitive to particle modifications that preceded the ligand conjugation. With the knowledge gained from this detailed distribution analysis, a new platform design was developed to provide a system with dramatically improved control over the number of components and with improved batch reproducibility. Using semi-preparative HPLC, individual dendrimer-ligand components were isolated. The isolated dendrimer with precise numbers of ligands were characterized by NMR and analytical HPLC. In total, nine different dendrimer-ligand components were obtained with degrees of purity ≥80%. This system has the potential to serve as a platform to which a precise number of functional molecules

Photovoltaic power for Space Station Freedom

NASA Technical Reports Server (NTRS)

Baraona, Cosmo R.

1990-01-01

Space Station Freedom is described with special attention given to its electric power system. The photovoltaic arrays, the battery energy storage system, and the power management, and distribution system are also discussed. The current design of Freedom's power system and the system requirements, trade studies, and competing factors which lead to system selections are referenced. This will be the largest power system ever flown in space. This system represents the culmination of many developments that have improved system performance, reduced cost, and improved reliability. Key developments and their evolution into the current space station solar array design are briefly described. The features of the solar cell and the array including the development, design, test, and flight hardware production status are given.

Photovoltaic power for Space Station Freedom

NASA Technical Reports Server (NTRS)

Baraona, Cosmo R.

1990-01-01

Space Station Freedom is described with special attention to its electric power system. The photovoltaic arrays, the battery energy storage system, and the power management and distribution system are also discussed. The current design of Freedom's power system and the system requirements, trade studies, and competing factors which lead to system selections are referenced. This will be the largest power system ever flown in space. This system represents the culmination of many developments that have improved system performance, reduced cost, and improved reliability. Key developments and their evolution into the current space station solar array design are briefly described. The features of the solar cell and the array including the development, design, test, and flight hardware production status are given.

Dose-finding designs for trials of molecularly targeted agents and immunotherapies

PubMed Central

Chiuzan, Cody; Shtaynberger, Jonathan; Manji, Gulam A.; Duong, Jimmy K.; Schwartz, Gary K.; Ivanova, Anastasia; Lee, Shing M.

2017-01-01

Recently, there has been a surge of early phase trials of molecularly targeted agents (MTAs) and immunotherapies. These new therapies have different toxicity profiles compared to cytotoxic therapies. MTAs can benefit from new trial designs that allow inclusion of low-grade toxicities, late-onset toxicities, addition of an efficacy endpoint, and flexibility in the specification of a target toxicity probability. To study the degree of adoption of these methods, we conducted a Web of Science search of articles published between 2008 and 2014 that describe phase 1 oncology trials. Trials were categorized based on the dose-finding design used and the type of drug studied. Out of 1,712 dose-finding trials that met our criteria, 1,591 (92.9%) utilized a rule-based design, and 92 (5.4%; range 2.3% in 2009 to 9.7% in 2014) utilized a model-based or novel design. Over half of the trials tested an MTA or immunotherapy. Among the MTA and immunotherapy trials, 5.8% used model-based methods, compared to 3.9% and 8.3% of the chemotherapy or radiotherapy trials, respectively. While the percentage of trials using novel dose-finding designs has tripled since 2007, only 7.1% of trials use novel designs. PMID:28166468

International Space Station: becoming a reality.

PubMed

David, L

1999-07-01

An overview of the development of the International Space Station (ISS) is presented starting with a brief history of space station concepts from the 1960's to the decision to build the present ISS. Other topics discussed include partnerships with Japan, Canada, ESA countries, and Russia; design changes to the ISS modules, the use of the ISS for scientific purposes and the application of space research to medicine on Earth; building ISS modules on Earth, international funding for Russian components, and the political aspects of including Russia in critical building plans. Sidebar articles examine commercialization of the ISS, multinational efforts in the design and building of the ISS, emergency transport to Earth, the use of robotics in ISS assembly, application of lessons learned from the Skylab project to the ISS, initial ISS assembly in May 1999, planned ISS science facilities, and an overview of space stations in science fiction.

Robust Constrained Optimization Approach to Control Design for International Space Station Centrifuge Rotor Auto Balancing Control System

NASA Technical Reports Server (NTRS)

Postma, Barry Dirk

2005-01-01

This thesis discusses application of a robust constrained optimization approach to control design to develop an Auto Balancing Controller (ABC) for a centrifuge rotor to be implemented on the International Space Station. The design goal is to minimize a performance objective of the system, while guaranteeing stability and proper performance for a range of uncertain plants. The Performance objective is to minimize the translational response of the centrifuge rotor due to a fixed worst-case rotor imbalance. The robustness constraints are posed with respect to parametric uncertainty in the plant. The proposed approach to control design allows for both of these objectives to be handled within the framework of constrained optimization. The resulting controller achieves acceptable performance and robustness characteristics.

Base Station Activation and Linear Transceiver Design for Optimal Resource Management in Heterogeneous Networks

NASA Astrophysics Data System (ADS)

Liao, Wei-Cheng; Hong, Mingyi; Liu, Ya-Feng; Luo, Zhi-Quan

2014-08-01

In a densely deployed heterogeneous network (HetNet), the number of pico/micro base stations (BS) can be comparable with the number of the users. To reduce the operational overhead of the HetNet, proper identification of the set of serving BSs becomes an important design issue. In this work, we show that by jointly optimizing the transceivers and determining the active set of BSs, high system resource utilization can be achieved with only a small number of BSs. In particular, we provide formulations and efficient algorithms for such joint optimization problem, under the following two common design criteria: i) minimization of the total power consumption at the BSs, and ii) maximization of the system spectrum efficiency. In both cases, we introduce a nonsmooth regularizer to facilitate the activation of the most appropriate BSs. We illustrate the efficiency and the efficacy of the proposed algorithms via extensive numerical simulations.

Crew quarters for Space Station

NASA Technical Reports Server (NTRS)

Mount, F. E.

1989-01-01

The only long-term U.S. manned space mission completed has been Skylab, which has similarities as well as differences to the proposed Space Station. With the exception of Skylab missions, there has been a dearth of experience on which to base the design of the individual Space Station Freedom crew quarters. Shuttle missions commonly do not have sleep compartments, only 'sleeping arrangements'. There are provisions made for each crewmember to have a sleep restraint and a sleep liner, which are attached to a bulkhead or a locker. When the Shuttle flights began to have more than one working shift, crew quarters became necessary due to noise and other disturbances caused by crew task-related activities. Shuttle missions that have planned work shifts have incorporated sleep compartments. To assist in gaining more information and insight for the design of the crew quarters for the Space Station Freedom, a survey was given to current crewmembers with flight experience. The results from this survey were compiled and integrated with information from the literature covering space experience, privacy, and human-factors issues.