International Conference on Harmonisation; Guidance on Q11 Development and Manufacture of Drug Substances; availability. Notice.

PubMed

2012-11-20

The Food and Drug Administration (FDA) is announcing the availability of a guidance entitled "Q11 Development and Manufacture of Drug Substances.'' The guidance was prepared under the auspices of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The guidance describes approaches to developing and understanding the manufacturing process of a drug substance and provides guidance on what information should be provided in certain sections of the Common Technical Document (CTD). The guidance is intended to harmonize the scientific and technical principles relating to the description and justification of the development and manufacturing process of drug substances (both chemical entities and biotechnological/biological entities) to enable a consistent approach for providing and evaluating this information across the three regions. The discussion of principles in the guidance is intended to apply only to the manufacture of drug substance, not the manufacture of finished drug products.

A Qualitative Inquiry of Career Exploration in Highly Implemented Career and Technical Education Programs of Study

ERIC Educational Resources Information Center

Stipanovic, Natalie; Stringfield, Sam

2013-01-01

This qualitative study explores career counseling and guidance services as provided to students engaged in career and technical education programs at three sites in the United States. The sites, consisting of high schools and community colleges, were part of the National Research Center for Career and Technical Education's 5-year studies of…

Patterns of Guidance in Inquiry Learning

ERIC Educational Resources Information Center

Veermans, Marjaana; Lallimo, Jiri; Hakkarainen, Kai

2005-01-01

The purpose of this case study was to examine a teacher's guidance of an inquiry learning project in an ordinary elementary-school classroom. The participants in the study were 21 Finnish, grade 4 students (10 years old), from which four students were selected for intensive observation. The technical infrastructure of the study was Computer…

School Organizational Innovative Indicators for Technical Universities and Institutes

ERIC Educational Resources Information Center

Chen, Su-Chang; Hsiao, Hsi-Chi; Chang, Jen-Chia; Shen, Chien-Hua; Chou, Chun-Mei

2010-01-01

This study aimed to construct the organizational innovation indicators of technical universities and institutes. This study held a group discussion and expert focus meeting and afterward, this study generalized seven facets of school organizational innovation: leadership innovation, administration innovation, student guidance and activity…

Cycle water chemistry based on film forming amines at power plants: evaluation of technical guidance documents

NASA Astrophysics Data System (ADS)

Dyachenko, F. V.; Petrova, T. I.

2017-11-01

Efficiency and reliability of the equipment in fossil power plants as well as in combined cycle power plants depend on the corrosion processes and deposit formation in steam/water circuit. In order to decrease these processes different water chemistries are used. Today the great attention is being attracted to the application of film forming amines and film forming amine products. The International Association for the Properties of Water and Steam (IAPWS) consolidated the information from all over the World, and based on the research studies and operating experience of researchers and engineers from 21 countries, developed and authorized the Technical Guidance Document: “Application of Film Forming Amines in Fossil, Combined Cycle, and Biomass Power Plants” in 2016. This article describe Russian and International technical guidance documents for the cycle water chemistries based on film forming amines at fossil and combined cycle power plants.

TECHNICAL GUIDANCE DOCUMENT: THE FABRICATION OF POLYETHYLENE FML FIELD SEAMS

EPA Science Inventory

This technical guidance document is meant to augment the numerous construction quality control and construction assurance (CQC and CQA) guidelines that are presently available for high density polyethylene (HDPE) liner installation and inspection.

Draft federal GHG accounting and reporting : technical support document

DOT National Transportation Integrated Search

2010-07-01

This is a technical support document (TSD) that accompanies the Federal Greenhouse Gas Accounting and Reporting Guidance (or Guidance). This document provides detailed information on the inventory reporting process and accepted calculation methodolog...

Technical bases and guidance for the use of composite soil sampling for demonstrating compliance with radiological release criteria

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vitkus, Timothy J.

2012-04-24

This guidance provides information on methodologies and the technical bases that licensees should consider for incorporating composite sampling strategies into final status survey (FSS) plans. In addition, this guidance also includes appropriate uses of composite sampling for generating the data for other decommissioning site investigations such as characterization or other preliminary site investigations.

TECHNICAL RESOURCE DOCUMENT ON MONITORED NATURAL RECOVERY

EPA Science Inventory

In 2005, the United States Environmental Protection Agency (EPA) published a document entitled Contaminated Sediment Remediation Guidance for Hazardous Waste Sites (EPA, 2005), which provides technical and policy guidance for project managers and teams making risk manageme...

Effects of a Velocity-Vector Based Command Augmentation System and Synthetic Vision System Terrain Portrayal and Guidance Symbology Concepts on Single-Pilot Performance

NASA Technical Reports Server (NTRS)

Liu, Dahai; Goodrich, Kenneth H.; Peak, Bob

2010-01-01

This study investigated the effects of synthetic vision system (SVS) concepts and advanced flight controls on the performance of pilots flying a light, single-engine general aviation airplane. We evaluated the effects and interactions of two levels of terrain portrayal, guidance symbology, and flight control response type on pilot performance during the conduct of a relatively complex instrument approach procedure. The terrain and guidance presentations were evaluated as elements of an integrated primary flight display system. The approach procedure used in the study included a steeply descending, curved segment as might be encountered in emerging, required navigation performance (RNP) based procedures. Pilot performance measures consisted of flight technical performance, perceived workload, perceived situational awareness and subjective preference. The results revealed that an elevation based generic terrain portrayal significantly improved perceived situation awareness without adversely affecting flight technical performance or workload. Other factors (pilot instrument rating, control response type, and guidance symbology) were not found to significantly affect the performance measures.

International Conference on Harmonisation; Guidance on M3(R2) Nonclinical Safety Studies for the Conduct of Human Clinical Trials and Marketing Authorization for Pharmaceuticals; availability. Notice.

PubMed

2010-01-21

The Food and Drug Administration (FDA) is announcing the availability of a guidance entitled "M3(R2) Nonclinical Safety Studies for the Conduct of Human Clinical Trials and Marketing Authorization for Pharmaceuticals.'' The guidance was prepared under the auspices of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The guidance, which is a revision of an existing guidance, discusses the types of nonclinical studies, their scope and duration, and their relation to the conduct of human clinical trials and marketing authorization for pharmaceuticals. The guidance is intended to facilitate the timely conduct of clinical trials and reduce the unnecessary use of animals and other drug development resources.

Maintaining the program balance, volumes 1 and 2

NASA Technical Reports Server (NTRS)

Finger, Harold

1991-01-01

In March of 1990, the NASA Administrator asked the Academy to perform a study to address the following questions: (1) has NASA contracted too much of its technical work; (2) has NASA's in-house technical capability eroded over time; (3) is in-house engineering and scientific work important to the development of scientists and engineers; and (4) is NASA still able to attract quality scientists and engineers. A panel from the Academy addressed each question separately and came up with the following recommendations: (1) prepare and issue guidance on technical functional areas reserved for in-house performance; (2) convert contracted technical functions to in-house performance if critical to agency programs; (3) provide policy guidance to the centers to retain in-house projects; (4) examine the project mix at each center against agency goals and objectives; (5) institute an annual critical review for all technical disciplines; (6) modify the agency's contractor accountability process; and (7) seek opportunities for greater delegation of resources and technical decision making.

75 FR 18497 - Guidance on Simultaneous Transmission Import Limit Studies for the Northwest Region; Notice of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-12

... Conference ``Guidance on Simultaneous Transmission Import Limit Studies.'' To view the archive of the...?ID=5001&CalType=%20&CalendarID=116&Date=12/16/2009&View=Listview and click on ``free live webcast.'' To view the slides from that technical conference, click on ``Staff Presentation'' at the same...

Development of mining guidance and control systems

NASA Technical Reports Server (NTRS)

1979-01-01

New fundamental interface sensor concepts were identified and investigated including tabulation of the physical and performance characteristics of two new interface detector concepts: - natural background radiation and magnetic spin resonance. Studies of guidance and control techniques for the longwall miner identified three basic systems for use in automated/remote controlled longwall mining. The following projects were initiated: system study which will more completely define the longwall guidance and control system design concepts; integration of the various control functions (vertical, yaw, and roll); and hardware technical requirements.

[The study of establishment of the " Chinese provincial Blindness prevention technical guidance group performance evaluation system"].

PubMed

Lu, L N; He, X G; Zhu, J F; Xu, X; Zhang, R; Hu, X; Zou, H D

2016-11-11

Objective: To establish an assessment system, including indexes and scoring methods, that can be used for performance evaluation of the provincial blindness prevention technical guidance group properly and effectively . Methods: The indexes and scoring methods were set based on the core content of The " National Plan of Prevention and Treatment of Blindness (2012-2015)" , the specific requirement and target of the World Health Organization (WHO) "For the General Eye Health: Global plan of Action (2014-2019)" , and the current situation of the China's provinces and autonomous regions. These indexes should be of effectiveness, feasibility, comparability, guidance and advancing. Formed by a literature review of candidate indicators, the framework of the system is built by qualitative assessment. With the Delphi method, the system was further revised and improved. Empirical pilot study was then used to prove the feasibility, followed by the final qualitative analysis that establish the " Chinese provincial Blindness prevention technical guidance group performance evaluation system" . Results: Through the literature review and qualitative assessment, a six dimensional system framework was built, including 6 first-level indicators, 16 second-level indicators, and 29 third-level indicators through Delphi method evaluation. With the variation coefficient method, the coeffiences of the first-level index weight were calculated as: Organization and management 0.15, Development and implementation of blindness prevention plans 0.15, Implementation of blindness prevention projects 0.14, Training 0.17, Health education 0.18, and Cooperation and exchanges 0.21. The specific scoring method for this system is confirmed as: data and files check, field interview, and record interview, sampling investigation. Empirical pilot study was conducted in the Jilin, Guizhou and Gansu provinces, and the self-assessment results from local experts were consistent with the scores from the systems. Conclusion: This system established is appropriate at current time, and it can effectively evaluate the performance of the Chinese provincial Blindness prevention technical guidance group. (Chin J Ophthalmol, 2016, 52:814-824) .

TECHNICAL GUIDANCE DOCUMENT: CONSTRUCTION QUALITY MANAGEMENT FOR REMEDIAL ACTION AND REMEDIAL DESIGN WASTE CONTAINMENT SYSTEMS

EPA Science Inventory

This Technical Guidance Document is intended to augment the numerous construction quality control and construction quality assurance (CQC and CQA) documents that are available far materials associated with waste containment systems developed for Superfund site remediation. In ge...

NUTRIENT CRITERIA TECHNICAL GUIDANCE MANUAL - ESTUARINE AND COASTAL MARINE WATERS, OCTOBER 2001

EPA Science Inventory

Nutrient overenrichment is a major cause of water pollution in the United States. The purpose of this manual is to provide scientifically defensible technical guidance to assist States, authorized Tribes, and other governmental entities in developing numeric nutrient criteria fo...

Technical and Regulatory Guidance Document for Constructed Treatment Wetlands

DTIC Science & Technology

2003-12-01

leachate and acid mine drainage. The purpose of this document is to provide technical and regulatory guidance to help regulators, industry, consultants...Contaminants at Industrial Facilities .....................41 Table 4-12 Typical Landfill Leachate Characteristics and Removal Efficiencies...43 Table 4-14 Landfill Leachate Characteristics

Development of Technical Basis for Burnup Credit Regulatory Guidance in the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parks, Cecil V; Wagner, John C; Mueller, Don

2011-01-01

In the United States (U.S.) there has been and continues to be considerable interest in the increased use of burnup credit as part of the safety basis for SNF systems and this interest has motivated numerous technical studies related to the application of burnup credit for maintaining subcriticality. Responding to industry requests and needs, the U.S. Nuclear Regulatory Commission initiated a burnup credit research program, with support from the Oak Ridge National Laboratory, to develop regulatory guidance and the supporting technical basis for allowing and expanding the use of burnup credit in pressurized-water reactor SNF storage and transport applications. Themore » objective of this paper is to summarize the work and significant accomplishments, with references to the technical reports and publications for complete details.« less

Accuracy of percutaneous soft-tissue interventions using a multi-axis, C-arm CT system and 3D laser guidance.

PubMed

Kostrzewa, Michael; Rathmann, Nils; Kara, Kerim; Schoenberg, Stefan O; Diehl, Steffen J

2015-10-01

Purpose of this phantom study was to compare the accuracy of needle placement using a multi-axis, C-arm-based, flat-panel, cone-beam computed tomography system (CBCT guidance) with that under multi-detector computed tomography guidance (MDCT guidance). In an abdominal phantom, eight lesions (six lesions in the liver and two in the renal pelvises, respectively) were each punctured in-plane and off-plane with a 20G needle under CBCT and MDCT guidance. Access paths were initially defined and reproduced identically on the two systems. In total, 32 interventions were conducted. CBCT and MDCT guidance was compared prospectively with respect to technical success, accuracy, and overall procedural time. All 32 interventions were technically successful in that it was possible to hit the respective lesion in each procedure. When comparing the accuracy of MDCT to CBCT guidance there was no significant difference in absolute, angular, and longitudinal deviation for either in- or off-plane interventions. Overall procedural duration was significantly longer under CBCT guidance for in-plane interventions (888 vs 527s, p=0.00005), whereas, for off-plane procedures there was no significant difference between CBCT and MDCT guidance (920 vs 701s, p=0.08). Off-plane interventions took significantly longer than in-plane interventions under MDCT guidance (701 vs 527s, p=0.03), whereas under CBCT guidance no significant difference could be found between off- and in-plane procedures (920 vs. 888s, p=0.2). In this phantom study, we could show that percutaneous soft-tissue interventions under CBCT guidance can be conducted with an accuracy comparable to that under MDCT guidance. Although overall procedural duration is in general shorter using MDCT guidance, CBCT-guided interventions offer the advantage of more degrees of freedom, which is of particular importance for off-plane procedures. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Percutaneous Bone Biopsies: Comparison between Flat-Panel Cone-Beam CT and CT-Scan Guidance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tselikas, Lambros, E-mail: lambros.tselikas@gmail.com; Joskin, Julien, E-mail: j.joskin@gmail.com; Roquet, Florian, E-mail: florianroquet@hotmail.com

2015-02-15

PurposeThis study was designed to compare the accuracy of targeting and the radiation dose of bone biopsies performed either under fluoroscopic guidance using a cone-beam CT with real-time 3D image fusion software (FP-CBCT-guidance) or under conventional computed tomography guidance (CT-guidance).MethodsSixty-eight consecutive patients with a bone lesion were prospectively included. The bone biopsies were scheduled under FP-CBCT-guidance or under CT-guidance according to operating room availability. Thirty-four patients underwent a bone biopsy under FP-CBCT and 34 under CT-guidance. We prospectively compared the two guidance modalities for their technical success, accuracy, puncture time, and pathological success rate. Patient and physician radiation doses also were compared.ResultsAll biopsiesmore » were technically successful, with both guidance modalities. Accuracy was significantly better using FP-CBCT-guidance (3 and 5 mm respectively: p = 0.003). There was no significant difference in puncture time (32 and 31 min respectively, p = 0.51) nor in pathological results (88 and 88 % of pathological success respectively, p = 1). Patient radiation doses were significantly lower with FP-CBCT (45 vs. 136 mSv, p < 0.0001). The percentage of operators who received a dose higher than 0.001 mSv (dosimeter detection dose threshold) was lower with FP-CBCT than CT-guidance (27 vs. 59 %, p = 0.01).ConclusionsFP-CBCT-guidance for bone biopsy is accurate and reduces patient and operator radiation doses compared with CT-guidance.« less

TECHNICAL APPROACHES TO CHARACTERIZING AND CLEANING UP BROWNFIELDS SITES: GUIDANCE DOCUMENT

EPA Science Inventory

NRMRL-CIN-1741 SAIC. Technical Approaches to Characterizing and Cleaning up Brownfields Sites. EPA/625/R/00/009 (NTIS PB2002-105021) , Available: 68-C7-0011. The guidance document gives assistance to communities, decision-makers, states and municipalities, academia, and the p...

Ultrasound-guided lumbar puncture in pediatric patients: technical success and safety.

PubMed

Pierce, David B; Shivaram, Giri; Koo, Kevin S H; Shaw, Dennis W W; Meyer, Kirby F; Monroe, Eric J

2018-06-01

Disadvantages of fluoroscopically guided lumbar puncture include delivery of ionizing radiation and limited resolution of incompletely ossified posterior elements. Ultrasound (US) allows visualization of critical soft tissues and the cerebrospinal fluid (CSF) space without ionizing radiation. To determine the technical success and safety of US-guided lumbar puncture in pediatric patients. A retrospective review identified all patients referred to interventional radiology for lumbar puncture between June 2010 and June 2017. Patients who underwent lumbar puncture with fluoroscopic guidance alone were excluded. For the remaining procedures, technical success and procedural complications were assessed. Two hundred and one image-guided lumbar punctures in 161 patients were included. Eighty patients (43%) had previously failed landmark-based attempts. One hundred ninety-six (97.5%) patients underwent lumbar puncture. Five procedures (2.5%) were not attempted after US assessment, either due to a paucity of CSF or unsafe window for needle placement. Technical success was achieved in 187 (95.4%) of lumbar punctures attempted with US guidance. One hundred seventy-seven (90.3%) were technically successful with US alone (age range: 2 days-15 years, weight range: 1.9-53.1 kg) and an additional 10 (5.1%) were successful with US-guided thecal access and subsequent fluoroscopic confirmation. Three (1.5%) cases were unsuccessful with US guidance but were subsequently successful with fluoroscopic guidance. Of the 80 previously failed landmark-based lumbar punctures, 77 (96.3%) were successful with US guidance alone. There were no reported complications. US guidance is safe and effective for lumbar punctures and has specific advantages over fluoroscopy in pediatric patients.

MRI-guidance in percutaneous core decompression of osteonecrosis of the femoral head.

PubMed

Kerimaa, Pekka; Väänänen, Matti; Ojala, Risto; Hyvönen, Pekka; Lehenkari, Petri; Tervonen, Osmo; Blanco Sequeiros, Roberto

2016-04-01

The purpose of this study was to evaluate the usefulness of MRI-guidance for core decompression of avascular necrosis of the femoral head. Twelve MRI-guided core decompressions were performed on patients with different stages of avascular necrosis of the femoral head. The patients were asked to evaluate their pain and their ability to function before and after the procedure and imaging findings were reviewed respectively. Technical success in reaching the target was 100 % without complications. Mean duration of the procedure itself was 54 min. All patients with ARCO stage 1 osteonecrosis experienced clinical benefit and pathological MRI findings were seen to diminish. Patients with more advanced disease gained less, if any, benefit and total hip arthroplasty was eventually performed on four patients. MRI-guidance seems technically feasible, accurate and safe for core decompression of avascular necrosis of the femoral head. Patients with early stage osteonecrosis may benefit from the procedure. • MRI is a useful guidance method for minimally invasive musculoskeletal interventions. • Bone drilling seems beneficial at early stages of avascular necrosis. • MRI-guidance is safe and accurate for bone drilling.

Technical Report for State and Local Public Health Officials and School Administrators on CDC Guidance for School (K-12) Responses to Influenza during the 2009-2010 School Year

ERIC Educational Resources Information Center

Centers for Disease Control and Prevention, 2009

2009-01-01

This Technical Report includes detailed information on the reasons for the strategies presented in the Centers for Disease Control (CDC) "Guidance for School (K-12) Responses to Influenza During the 2009-2010 School Year" and suggestions on how to use them. The guidance is designed to decrease exposure to regular seasonal flu and 2009 H1N1 flu…

75 FR 16345 - Administrative Practices and Procedures; Good Guidance Practices; Technical Amendment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-01

.... FDA-1999-N-3539] (formerly Docket No. 1999N-4783) Administrative Practices and Procedures; Good Guidance Practices; Technical Amendment AGENCY: Food and Drug Administration, HHS. ACTION: Final rule... Subjects in 21 CFR Part 10 Administrative practice and procedure, News media. 0 Therefore, under the...

Radon Reduction Techniques in Schools: Interim Technical Guidance.

ERIC Educational Resources Information Center

Environmental Protection Agency, Washington, DC.

This technical document is intended to assist school facilities maintenance personnel in the selection, design, and operation of radon reduction systems in schools. The guidance contained in this document is based largely on research conducted in 1987 and 1988 in schools located in Maryland and Virginia. Researchers from the United States…

RADON REDUCTION TECHNIQUES FOR EXISTING DETACHED HOUSES - TECHNICAL GUIDANCE (THIRD EDITION) FOR ACTIVE SOIL DEPRESSURIZATION SYSTEMS

EPA Science Inventory

This technical guidance document is designed to aid in the selection, design, installation and operation of indoor radon reduction techniques using soil depressurization in existing houses. Its emphasis is on active soil depressurization; i.e., on systems that use a fan to depre...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

At the request of the Office of Solid Wastes (OSW), the SAB's Environmental Engineering Committee reviewed a draft Agency guidance for the establishment of Alternate Concentration Limits (ACL) for Resource Conservation and Recovery Act (RCRA) facilities, and two case studies demonstrating applications of the guidance. The Committee identified only obvious technical errors or omissions, which are explained in detail in the report.

Developing the revised NICE appraisal technical guidance to manufacturers and sponsors: opportunity or threat?

PubMed

Taylor, Rod S; Hutton, John; Culyer, Anthony J

2002-01-01

One of the principal roles of the National Institute for Clinical Excellence (NICE) is to appraise selected existing and emerging healthcare technologies and, as a result, produce guidance for the National Health Service (NHS) in England and Wales. A central part of this appraisal is the potential for manufacturers and sponsors to make a data submission. This paper describes the process of development of the second edition of technical guidance to manufacturers and sponsors for submission to NICE. The revision process took place during the period May 2000 and January 2001 and involved a number of key steps -- establishment of a guidance steering committee, review of current international guidelines of clinical and cost effectiveness, drafting of the guidance, detailed consultation with stakeholders, revision of the guidance and, finally, publication. The lessons learnt from revision of the NICE guidance for manufacturers and sponsors and some main issues for its future development are discussed.

International Conference on Harmonisation; Guidance on E7 Studies in Support of Special Populations; Geriatrics; Questions and Answers; availability. Notice.

PubMed

2012-02-21

The Food and Drug Administration (FDA) is announcing the availability of a guidance entitled ``E7 Studies in Support of Special Populations: Geriatrics; Questions and Answers.'' The guidance was prepared under the auspices of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The questions and answers (Q&A) guidance addresses special considerations for the design and conduct of clinical trials of drugs likely to have significant use in the elderly. The Q&As are intended to provide guidance on the use of geriatric data to adequately characterize and represent the safety and efficacy of a drug for a marketing application, including data collected postmarketing.

Intravascular US-Guided Portal Vein Access: Improved Procedural Metrics during TIPS Creation.

PubMed

Gipson, Matthew G; Smith, Mitchell T; Durham, Janette D; Brown, Anthony; Johnson, Thor; Ray, Charles E; Gupta, Rajan K; Kondo, Kimi L; Rochon, Paul J; Ryu, Robert K

2016-08-01

To evaluate transjugular intrahepatic portosystemic shunt (TIPS) outcomes and procedure metrics with the use of three different image guidance techniques for portal vein (PV) access during TIPS creation. A retrospective review of consecutive patients who underwent TIPS procedures for a range of indications during a 28-month study period identified a population of 68 patients. This was stratified by PV access techniques: fluoroscopic guidance with or without portography (n = 26), PV marker wire guidance (n = 18), or intravascular ultrasound (US) guidance (n = 24). Procedural outcomes and procedural metrics, including radiation exposure, contrast agent volume used, procedure duration, and PV access time, were analyzed. No differences in demographic or procedural characteristics were found among the three groups. Technical success, technical success of the primary planned approach, hemodynamic success, portosystemic gradient, and procedure-related complications were not significantly different among groups. Fluoroscopy time (P = .003), air kerma (P = .01), contrast agent volume (P = .003), and total procedural time (P = .02) were reduced with intravascular US guidance compared with fluoroscopic guidance. Fluoroscopy time (P = .01) and contrast agent volume (P = .02) were reduced with intravascular US guidance compared with marker wire guidance. Intravascular US guidance of PV access during TIPS creation not only facilitates successful TIPS creation in patients with challenging anatomy, as suggested by previous investigations, but also reduces important procedure metrics including radiation exposure, contrast agent volume, and overall procedure duration compared with fluoroscopically guided TIPS creation. Copyright © 2016 SIR. Published by Elsevier Inc. All rights reserved.

Integrating research, legal technical assistance, and advocacy to inform shared use legislation in Mississippi.

PubMed

Spengler, John O; Frost, Natasha R; Bryant, Katherine K

2014-01-01

The purpose of this article was to describe the process by which research findings informed the successful passage of legislation designed to increase opportunities for physical activity in Mississippi, and discuss implications and lessons learned from this process. The article is descriptive and conceptual, and addresses the collaborative process by which research, legal technical assistance, and advocacy informed and shaped shared use legislation in Mississippi. Collaborators informing this article were an Active Living Research grantee, a staff attorney with the Public Health Law Center, the American Heart Association Mississippi Government Relations Director, and community partners. The American Heart Association and Public Health Law Center developed policy guidance in the form of sample language for legislation as a starting point for states in determining policy needed to eliminate or reduce barriers to the shared use of school recreational facilities. The policy guidance was informed by evidence from Active Living Research-funded research studies. The American Heart Association, supporting a bill shaped by the policy guidance, led the effort to advocate for successful shared use legislation in Mississippi. Research should be policy relevant and properly translated and disseminated. Legal technical assistance should involve collaboration with both researchers and advocates so that policymakers have the information to make evidence-based decisions. Government relations directors should collaborate with legal technical staff to obtain and understand policy guidance relevant to their advocacy efforts. Effective collaborations, with an evidence-based approach, can lead to informed, successful policy change.

TECHNICAL GUIDANCE FOR THE APPLICATION OF CAFO MANURE TO LAND IN THE WINTER

EPA Science Inventory

The purpose of the paper is to present technical guidance to which EPA Region 5 will refer as we work together with those states that intend to allow concentrated animal feeding operations to apply manure to land in the winter. For this purpose, Region 5 assumes that the risk of...

76 FR 57058 - International Cooperation on Harmonisation of Technical Requirements for Registration of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-15

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-D-0165] International Cooperation on Harmonisation of Technical Requirements for Registration of Veterinary Medicinal Products; Guidance for Industry on Studies To Evaluate the Metabolism and Residue Kinetics of Veterinary...

Ultrasound-Guided Radiofrequency Ablation Using a New Electrode with an Electromagnetic Position Sensor for Hepatic Tumors Difficult to Place an Electrode: A Preliminary Clinical Study.

PubMed

Kang, Tae Wook; Lee, Min Woo; Song, Kyoung Doo; Rhim, Hyunchul; Lim, Hyo Keun; Kang, Wonseok; Kim, Kyunga

2017-12-01

To evaluate whether a new electrode embedded with an electromagnetic position sensor (EMPS) improves the technical feasibility of percutaneous radiofrequency ablation (RFA) in patients with hepatic tumors difficult to place an electrode under ultrasonography (US) guidance and to assess short-term therapeutic efficacy and safety. This prospective study was approved by the institutional review board, and written informed consent was obtained from all patients. Between January 2015 and December 2016, 10 patients (7 men and 3 women; age range 52-75 years) with a single hepatic tumor (median 1.4 cm; range 1.1-1.8 cm) difficult to place an electrode under US guidance were enrolled. The technical feasibility of targeting and overlapping ablation during the RFA procedure was graded using a four-point scale and analyzed using the Wilcoxon signed rank test according to the use of EMPS. In addition, the rates of technical success, local tumor progression (LTP), and major complications were assessed. The use of the new RF electrode with EMPS significantly improved the technical feasibility of targeting and overlapping ablation (p = 0.002 and p = 0.003, respectively). After treatment, the technical success rate was 100%. LTP was not found in any patient during the follow-up period (median 8 months; range 4-22 months). No major procedure-related complications occurred. The technical feasibility of percutaneous RFA improves with the use of this RF electrode embedded with an EMPS. Short-term therapeutic efficacy and safety after RFA using the electrode were promising in patients with hepatic tumors difficult to place an electrode under US guidance.

75 FR 68364 - Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-05

... European Protocol for the Quality Control of the Physical and Technical Aspects of Mammography Screening... entitled ``Physical Laboratory Testing, Breast Compression System'' to follow the Mammography Quality...] Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance Document...

State-Level Guidance and District-Level Policies and Practices for Food Marketing in US School Districts.

PubMed

Merlo, Caitlin L; Michael, Shannon; Brener, Nancy D; Blanck, Heidi

2018-06-07

State agencies play a critical role in providing school districts with guidance and technical assistance on school nutrition issues, including food and beverage marketing practices. We examined associations between state-level guidance and the policies and practices in school districts regarding food and beverage marketing and promotion. State policy guidance was positively associated with districts prohibiting advertisements for junk food or fast food restaurants on school property. Technical assistance from states was negatively associated with 2 district practices to restrict marketing of unhealthy foods and beverages, but positively associated with 1 practice to promote healthy options. These findings may help inform the guidance that states provide to school districts and help identify which districts may need additional assistance to address marketing and promotion practices.

77 FR 39959 - Draft Guidance To Implement Requirements for the Treatment of Air Quality Monitoring Data...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-06

... of the revised draft High Winds Guidance document, the EPA identifies example technical analyses that... identified analyses and any additional technical analyses that air agencies could use to demonstrate that the... Web site at http://www.epa.gov/ttn/analysis/exevents.htm for additional details on the draft non...

A Critical Analysis of UNESCO's International Technical Guidance on School-Based Education for Puberty and Sexuality

ERIC Educational Resources Information Center

Goldman, Juliette D. G.

2012-01-01

Preparing children and adolescents for sexual safety and reproductive responsibility lies at the heart and purpose of puberty/sexuality education. The document of International Technical Guidance released by UNESCO in December 2009 aims to provide an evidence-based and rights-based platform offering children and adolescents vital knowledge about…

33 CFR 385.5 - Guidance memoranda.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Water Management District shall, in consultation with the Department of the Interior, the Environmental... DEFENSE PROGRAMMATIC REGULATIONS FOR THE COMPREHENSIVE EVERGLADES RESTORATION PLAN General Provisions § 385.5 Guidance memoranda. (a) General. (1) Technical guidance for internal management of Corps of...

33 CFR 385.5 - Guidance memoranda.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Water Management District shall, in consultation with the Department of the Interior, the Environmental... DEFENSE PROGRAMMATIC REGULATIONS FOR THE COMPREHENSIVE EVERGLADES RESTORATION PLAN General Provisions § 385.5 Guidance memoranda. (a) General. (1) Technical guidance for internal management of Corps of...

33 CFR 385.5 - Guidance memoranda.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Water Management District shall, in consultation with the Department of the Interior, the Environmental... DEFENSE PROGRAMMATIC REGULATIONS FOR THE COMPREHENSIVE EVERGLADES RESTORATION PLAN General Provisions § 385.5 Guidance memoranda. (a) General. (1) Technical guidance for internal management of Corps of...

Consultants' Report to West Virginia State College and Community and Technical College Study Commission: Observations and Recommendations.

ERIC Educational Resources Information Center

Boone, Edgar J.; Vaughan, George B.

West Virginia State College entered into a contract with two professors from North Carolina State University to provide consultation and guidance to the West Virginia State College-Community and Technical College (WVSC-CTC) Study Commission. Findings and recommendations include: (1) the strengths of the CTC, as seen by its community, are the…

Space station automation study: Autonomous systems and assembly, volume 2

NASA Technical Reports Server (NTRS)

Bradford, K. Z.

1984-01-01

This final report, prepared by Martin Marietta Denver Aerospace, provides the technical results of their input to the Space Station Automation Study, the purpose of which is to develop informed technical guidance in the use of autonomous systems to implement space station functions, many of which can be programmed in advance and are well suited for automated systems.

Transportation Conformity

EPA Pesticide Factsheets

This section provides information on: current laws, regulations and guidance, policy and technical guidance, project-level conformity, general information, contacts and training, adequacy review of SIP submissions

48 CFR 825.870 - Technical assistance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Technical assistance. 825... SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Other International Agreements and Coordination 825.870 Technical assistance. Contracting officers may obtain technical information or guidance on international agreements and...

A STUDY OF A NEW AND DRAMATIC APPROACH TO VOCATIONAL GUIDANCE THROUGH THE USE OF EXHIBITS AND DISPLAYS.

ERIC Educational Resources Information Center

WALSH, GEORGE A.

THIS IS A DESCRIPTION OF A NEW APPROACH TO VOCATIONAL GUIDANCE THROUGH THE USE OF EXHIBITS AND DISPLAYS. THE CHOICE OF APPROXIMATELY 150 SPECIFIC OCCUPATIONS TO BE EXHIBITED WAS BASED ON SUCH CRITERIA AS (1) PROJECTED NUMBER OF WORKERS IN EACH OCCUPATION, (2) APPEAL OF SELECTED OCCUPATIONS TO SECONDARY, TRADE, AND TECHNICAL SCHOOLS, (3) APPEAL OF…

A Differential Feature-Cost Analysis of Fifteen Computer-Assisted Career Guidance Systems: Technical Report Number 10. (Fourth Edition).

ERIC Educational Resources Information Center

Sampson, James P., Jr.; And Others

This study examined similarities and differences among 15 computer-assisted career guidance (CACG) systems: (1) the Career Information System; (2) Choices; (3) Choices CT; (4) Choices Jr; (5) MODULAR C-LECT; (6) COIN; (7) COIN Jr; (8) DISCOVER for Colleges and Adults; (9) DISCOVER for High Schools; (10) DISCOVER for Junior High and Middle Schools;…

Family of Advanced Beyond Line-of-Sight Terminals (FAB-T)

DTIC Science & Technology

2015-12-01

Architecture (DoD IEA), excepting tactical and non- operational (OP) communications 3) Compliant with GIG Technical Guidance ( GTG ) to include...Information Technology (IT) standards identified in the Standards FAB-T December 2015 SAR March 21, 2016 15:24:15 UNCLASSIFIED 24 Technical Guidance ( GTG ...Availability Anti-spoofing Module (SAASM), Spectrum and Joint Tactical Radio System (JTRS) requirements. Compliant GTG to include IT standards

LANGUAGE LABORATORY FACILITIES, TECHNICAL GUIDE FOR THE SELECTION, PURCHASE, USE, AND MAINTENANCE, STUDY 4--NEW MEDIA FOR INSTRUCTION.

ERIC Educational Resources Information Center

HAYES, ALFRED S.

THE MANY POSSIBLE VARIATIONS OF LANGUAGE LABORATORY SYSTEMS WERE DESCRIBED, AND RELATIVE ADVANTAGES AND LIMITATIONS OF EACH WERE DISCUSSED. DETAILED GUIDANCE ON PURCHASING LANGUAGE LABORATORY EQUIPMENT WAS PROVIDED THROUGH (1) DEFINITION OF HIGH-QUALITY SPEECH REPRODUCTION, (2) DISCUSSION OF TECHNICAL FACTORS WHICH AFFECT ITS ACHIEVEMENT, AND (3)…

Safe abortion: WHO technical and policy guidance.

PubMed

Cook, R J; Dickens, B M; Horga, M

2004-07-01

In 2003, the World Health Organization published its well referenced handbook Safe Abortion: Technical and Policy Guidance for Health Systems to address the estimated almost 20 million induced abortions each year that are unsafe, imposing a burden of approximately 67 thousand deaths annually. It is a global injustice that 95% of unsafe abortions occur in developing countries. The focus of guidance is on abortion procedures that are lawful within the countries in which they occur, noting that in almost all countries, the law permits abortion to save a woman's life. The guidance treats unsafe abortion as a public health challenge, and responds to the problem through strategies concerning improved clinical care for women undergoing procedures, and the appropriate placement of necessary services. Legal and policy considerations are explored, and annexes present guidance to further reading, international consensus documents on safe abortion, and on manual vacuum aspiration and post-abortion contraception.

Septic Systems Guidance, Policy, and Regulations

EPA Pesticide Factsheets

EPA has developed several documents outlining its mission, priorities and regulatory authorities as well as guidance and technical information to help communities establish comprehensive septic (onsite) management programs.

Space station automation study. Volume 1: Executive summary. Autonomous systems and assembly

NASA Technical Reports Server (NTRS)

1984-01-01

The purpose of the Space Station Automation Study (SSAS) was to develop informed technical guidance for NASA personnel in the use of autonomy and autonomous systems to implement space station functions.

The Use of Vocational Guidance E-Systems in Colleges of Technology, Saudi Arabia

NASA Astrophysics Data System (ADS)

Alsaidan, Saad; Zhang, Li

2018-01-01

This study aimed to explore how much interest do technical colleges students have in vocational guidance E-Systems and to detect the most important E-Systems of vocational guidance that they use. The researcher collected data, through questionnaires, from 311 students in their fourth, fifth, or sixth semesters in the colleges of technology in Saudi Arabia. The data were analysed using the chi square test, factor analysis, and descriptive analysis. This study shows the importance in the integration of the E-Systems to vocational guidance. The model includes: the use of e-vocational consulting programs, e-extracurricular programs, e-vocational activities, informational systems, and e-exams for vocational tendency, which were rarely studied before. The results indicated that the college student is highly motivated by vocational guidance using the E-system, unlike the traditional methods of vocational guidance, and young students are motivated by the E-system when it is used in vocational guidance. The study conclude that the integration of the E-system has significantly contributed to vocational guidance. The study recommends that the e-system be implemented to all areas of decision-making. Practitioners should Interact with students through the E-Systems and arrive at decisions that are good for educational growth.

EPA Policy and Guidance

EPA Pesticide Factsheets

The policy establishes the principles for accessible Electronic and Information Technology (EIT) and complying with Section 508 requirements. The guidance defines EIT and the technical and functional performance criteria necessary for compliance.

Stressor Identification Guidance Document

EPA Science Inventory

EPA has made availabile the Stressor Identification Guidance Document (EPA 822-B-00-025) published under the authority of Section 304(a)(2) of the Clean Water Act (CWA). This technical guidance doc...

33 CFR 385.5 - Guidance memoranda.

Code of Federal Regulations, 2010 CFR

2010-07-01

... sources of water will occur as a result of implementation of the Plan (§ 385.36(b)). (b) Special processes..., implementation, and management of one specific individual feature of the Plan, this section does not require... § 385.5 Guidance memoranda. (a) General. (1) Technical guidance for internal management of Corps of...

Adapting HIV prevention evidence-based interventions in practice settings: an interview study

PubMed Central

2009-01-01

Background Evidence-based interventions that are being delivered in real-world settings are adapted to enhance the external validity of these interventions. The purpose of this study was to examine multiple intervention adaptations made during pre-implementation, implementation, maintenance, and evolution phases of human immunodeficiency virus HIV prevention technology transfer. We examined two important categories of adaptations -- modifications to key characteristics, such as activities or delivery methods of interventions and reinvention of the interventions including addition and deletion of core elements. Methods Study participants were thirty-four community-based organization staff who were implementing evidence-based interventions in Los Angeles, California. Participants were interviewed twice and interviews were professionally transcribed. Transcriptions were coded by two coders with good inter-rater reliability (kappa coefficient = 0.73). Sixty-two open-ended codes for adaptation activities, which were linked to 229 transcript segments, were categorized as modifications of key characteristics or reinvention. Results Participants described activities considered modifications to key characteristics and reinvention of evidence-based interventions during pre-implementation, implementation, and maintenance phases. None of the participants reported accessing technical assistance or guidance when reinventing their interventions. Staff executed many of the recommended steps for sound adaptation of these interventions for new populations and settings. Conclusion Staff reported modifying and reinventing interventions when translating HIV prevention programs into practice. Targeted technical assistance for formative evaluation should be focused on the pre-implementation phase during which frequent modifications occur. Continuous or repeated measurements of fidelity are recommended. Increased technical assistance and guidance are needed to ensure that reinventions are evaluated and consistent with the aims of the original interventions. Providing strategic technical assistance and written guidance can facilitate effective HIV prevention technology transfer of evidence-based interventions. PMID:19930653

Removal of Retrievable Self-Expandable Metallic Tracheobronchial Stents: An 18-Year Experience in a Single Center.

PubMed

Park, Jung-Hoon; Kim, Pyeong Hwa; Shin, Ji Hoon; Tsauo, Jiaywei; Kim, Min Tae; Cho, Young Chul; Kim, Jin Hyoung; Song, Ho-Young

2016-11-01

The purpose of the study was to retrospectively evaluate the technical outcomes of removal of retrievable self-expandable metallic stents (REMSs) and identify predictors of technical failure in 81 patients with benign and malignant tracheobronchial strictures. A total of 98 REMSs were removed under fluoroscopic guidance in 81 patients with benign (n = 48) or malignant (n = 33) tracheobronchial strictures. Primary and secondary technical success rates and complication rate were evaluated. Technical outcomes with regard to underlying diseases were also evaluated. Logistic regression models were constructed to identify predictors of primary technical success. Primary and secondary technical success rates were 86.7 and 94.9 %, respectively. Stent removal-related complication rate was 7.1 % (7/98) and all were bleeding after stent removal. All bleeding complications were minor and managed conservatively. Primary technical success rate for benign strictures was significantly lower compared with that for malignant strictures (80.9 vs. 97.1 %, P = 0.029), but secondary technical success rate (93.7 vs. 97.1 %, P = 0.652) did not differ between the two groups. Granulation tissue formation was identified as an independent predictor of primary technical success (odds ratio 0.249, 95 % CI 0.071-0.874, P = 0.030). Removal of REMSs in patients with benign and malignant tracheobronchial strictures is safe and technically feasible. Bronchoscopic guidance may be required when the removal using a hook wire fails. The presence of granulation tissue was the negative predictor of primary technical success.

ERLN Technical Support for Labs

EPA Pesticide Factsheets

The Environmental Response Laboratory Network provides policies and guidance on lab and data requirements, Standardized Analytical Methods, and technical support for water and radiological sampling and analysis

FHWA road tunnel design guidelines

DOT National Transportation Integrated Search

2004-07-01

This document provides technical criteria and guidance for the planning and design of road tunnels. Specific areas covered include planning, studies and investigations, design, and design of construction, of tunnels and shafts. Performance concepts a...

Policy and Technical Guidance for State and Local Transportation

EPA Pesticide Factsheets

This page contains policy guidance issued by EPA and/or the U.S. Department of Transportation to assist state and local transportation and air quality agencies implement the transportation conformity program.

Applying human rights to maternal health: UN Technical Guidance on rights-based approaches.

PubMed

Yamin, Alicia Ely

2013-05-01

In the last few years there have been several critical milestones in acknowledging the centrality of human rights to sustainably addressing the scourge of maternal death and morbidity around the world, including from the United Nations Human Rights Council. In 2012, the Council adopted a resolution welcoming a Technical Guidance on rights-based approaches to maternal mortality and morbidity, and calling for a report on its implementation in 2 years. The present paper provides an overview of the contents and significance of the Guidance. It reviews how the Guidance can assist policymakers in improving women's health and their enjoyment of rights by setting out the implications of adopting a human rights-based approach at each step of the policy cycle, from planning and budgeting, to ensuring implementation, to monitoring and evaluation, to fostering accountability mechanisms. The Guidance should also prove useful to clinicians in understanding rights frameworks as applied to maternal health. Copyright © 2013 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

ITS deployment guidance for transit systems : technical edition

DOT National Transportation Integrated Search

1997-04-01

This document provides guidance for the transit community on developing and implementing Intelligent Transportation Systems (ITS) and using the National ITS Architecture. It is written specifically for the transit community and focuses on transit app...

78 FR 52776 - Documents to Support Submission of an Electronic Common Technical Document; Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-26

... obtain the documents at either http://www.fda.gov/Drugs/DevelopmentApprovalProcess/FormsSubmission...BloodVaccines/GuidanceComplianceRegulatoryInformation/Guidances/default.htm . Dated: August 20, 2013...

76 FR 66311 - Draft Documents To Support Submission of an Electronic Common Technical Document; Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-26

.../DevelopmentApprovalProcess/FormsSubmissionRequirements/ElectronicSubmissions/ucm253101.htm , http://www.fda.gov/BiologicsBloodVaccines/GuidanceComplianceRegulatoryInformation/Guidances/default.htm , or http...

78 FR 10181 - Documents To Support Submission of an Electronic Common Technical Document; Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-13

... obtain the documents at either http://www.fda.gov/Drugs/DevelopmentApprovalProcess/FormsSubmission...BloodVaccines/GuidanceComplianceRegulatoryInformation/Guidances/default.htm . Dated: February 8, 2013...

Orbital transfer vehicle concept definition and system analysis study. Volume 2: OTV concept definition and evaluation. Book 3: Subsystem trade studies

NASA Technical Reports Server (NTRS)

Dickman, Glen J.

1987-01-01

The technical trade studies and analyses reported in this book represent the accumulated work of the technical staff for the contract period. The general disciplines covered are as follows: (1) Guidance, Navigation, and Control; (2) Avionics Hardware; (3) Aeroassist Technology; (4) Propulsion; (5) Structure and Materials; and (6) Thermal Control Technology. The objectives in each of these areas were to develop the latest data, information, and analyses in support of the vehicle design effort.

75 FR 5784 - Guidance on Preparation of Market-Based Rate Filings and Electric Quarterly Reports by Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-04

... Preparation of Market-Based Rate Filings and Electric Quarterly Reports by Public Utilities; Notice of Technical Conference January 28, 2010. Take notice that Commission staff will convene a technical conference... final agenda of the technical conference. The March 3, 2010 technical conference will focus on the...

A proposal to revive "parent guidance": an illustration of a brief intervention with the mother of a toddler.

PubMed

Sherick, Ivan

2009-01-01

A parent guidance intervention is illustrated. The value of such work is underscored to help parents and candidates in child analysis understand intergenerational psychopathology and its consequences for a child. Technical considerations of parent guidance are addressed. A revival of such work is advocated in child analysis training programs.

Career Guidance--Now and Then: High Tech and High Touch

ERIC Educational Resources Information Center

Newell, Eugenia

2010-01-01

There is a lot new in career guidance. Technology is a driving force in the workplace, and it has changed how educators teach and what they teach. The digital age has provided new depth to career awareness and exploration and new responsibilities for career guidance professionals. As career and technical teachers must be current with software and…

78 FR 22554 - Document to Support Submission of an Electronic Common Technical Document-Specifications for File...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-16

... documents at either http://www.fda.gov/Drugs/DevelopmentApprovalProcess/FormsSubmissionRequirements...Vaccines/GuidanceComplianceRegulatoryInformation/Guidances/default.htm . Dated: April 10, 2013. Leslie Kux...

Regulatory Guidance for Lightning Protection in Nuclear Power Plants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kisner, Roger A; Wilgen, John B; Ewing, Paul D

2006-01-01

Abstract - Oak Ridge National Laboratory (ORNL) was engaged by the U.S. Nuclear Regulatory Commission (NRC) Office of Nuclear Regulatory Research (RES) to develop the technical basis for regulatory guidance to address design and implementation practices for lightning protection systems in nuclear power plants (NPPs). Lightning protection is becoming increasingly important with the advent of digital and low-voltage analog systems in NPPs. These systems have the potential to be more vulnerable than older analog systems to the resulting power surges and electromagnetic interference (EMI) when lightning strikes facilities or power lines. This paper discusses the technical basis for guidance tomore » licensees and applicants covered in Regulatory Guide (RG) 1.204, Guidelines for Lightning Protection of Nuclear Power Plants, issued August 2005. RG 1.204 describes guidance for practices that are acceptable to the NRC staff for protecting nuclear power structures and systems from direct lightning strikes and the resulting secondary effects.« less

Regulatory guidance for lightning protection in nuclear power plants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kisner, R. A.; Wilgen, J. B.; Ewing, P. D.

2006-07-01

Oak Ridge National Laboratory (ORNL) was engaged by the U.S. Nuclear Regulatory Commission (NRC) Office of Nuclear Regulatory Research (RES) to develop the technical basis for regulatory guidance to address design and implementation practices for lightning protection systems in nuclear power plants (NPPs). Lightning protection is becoming increasingly important with the advent of digital and low-voltage analog systems in NPPs. These systems have the potential to be more vulnerable than older analog systems to the resulting power surges and electromagnetic interference (EMI) when lightning strikes facilities or power lines. This paper discusses the technical basis for guidance to licensees andmore » applicants covered in Regulatory Guide (RG) 1.204, Guidelines for Lightning Protection of Nuclear Power Plants, issued August 2005. RG 1.204 describes guidance for practices that are acceptable to the NRC staff for protecting nuclear power structures and systems from direct lightning strikes and the resulting secondary effects. (authors)« less

Removal of Retrievable Self-Expandable Metallic Tracheobronchial Stents: An 18-Year Experience in a Single Center

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, Jung-Hoon; Kim, Pyeong Hwa; Shin, Ji Hoon, E-mail: jhshin@amc.seoul.kr

2016-11-15

PurposeThe purpose of the study was to retrospectively evaluate the technical outcomes of removal of retrievable self-expandable metallic stents (REMSs) and identify predictors of technical failure in 81 patients with benign and malignant tracheobronchial strictures.Materials and MethodsA total of 98 REMSs were removed under fluoroscopic guidance in 81 patients with benign (n = 48) or malignant (n = 33) tracheobronchial strictures. Primary and secondary technical success rates and complication rate were evaluated. Technical outcomes with regard to underlying diseases were also evaluated. Logistic regression models were constructed to identify predictors of primary technical success.ResultsPrimary and secondary technical success rates were 86.7 and 94.9 %, respectively.more » Stent removal-related complication rate was 7.1 % (7/98) and all were bleeding after stent removal. All bleeding complications were minor and managed conservatively. Primary technical success rate for benign strictures was significantly lower compared with that for malignant strictures (80.9 vs. 97.1 %, P = 0.029), but secondary technical success rate (93.7 vs. 97.1 %, P = 0.652) did not differ between the two groups. Granulation tissue formation was identified as an independent predictor of primary technical success (odds ratio 0.249, 95 % CI 0.071–0.874, P = 0.030).ConclusionRemoval of REMSs in patients with benign and malignant tracheobronchial strictures is safe and technically feasible. Bronchoscopic guidance may be required when the removal using a hook wire fails. The presence of granulation tissue was the negative predictor of primary technical success.« less

48 CFR 216.402-2 - Technical performance incentives.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Technical performance incentives. 216.402-2 Section 216.402-2 Federal Acquisition Regulations System DEFENSE ACQUISITION... Contracts 216.402-2 Technical performance incentives. See PGI 216.402-2 for guidance on establishing...

77 FR 18271 - Terrestrial Environmental Studies for Nuclear Power Stations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-27

... NUCLEAR REGULATORY COMMISSION [NRC-2011-0182] Terrestrial Environmental Studies for Nuclear Power... Environmental Studies for Nuclear Power Stations.'' This guide provides technical guidance that the NRC staff... nuclear power reactors. ADDRESSES: Please refer to Docket ID NRC-2011-0182 when contacting the NRC about...

Piloted Simulation of Various Synthetic Vision Systems Terrain Portrayal and Guidance Symbology Concepts for Low Altitude En-Route Scenario

NASA Technical Reports Server (NTRS)

Takallu, M. A.; Glaab, L. J.; Hughes, M. F.; Wong, D. T.; Bartolone, A. P.

2008-01-01

In support of the NASA Aviation Safety Program's Synthetic Vision Systems Project, a series of piloted simulations were conducted to explore and quantify the relationship between candidate Terrain Portrayal Concepts and Guidance Symbology Concepts, specific to General Aviation. The experiment scenario was based on a low altitude en route flight in Instrument Metrological Conditions in the central mountains of Alaska. A total of 18 general aviation pilots, with three levels of pilot experience, evaluated a test matrix of four terrain portrayal concepts and six guidance symbology concepts. Quantitative measures included various pilot/aircraft performance data, flight technical errors and flight control inputs. The qualitative measures included pilot comments and pilot responses to the structured questionnaires such as perceived workload, subjective situation awareness, pilot preferences, and the rare event recognition. There were statistically significant effects found from guidance symbology concepts and terrain portrayal concepts but no significant interactions between them. Lower flight technical errors and increased situation awareness were achieved using Synthetic Vision Systems displays, as compared to the baseline Pitch/Roll Flight Director and Blue Sky Brown Ground combination. Overall, those guidance symbology concepts that have both path based guidance cue and tunnel display performed better than the other guidance concepts.

Assessment of vocational guidance: the Berufsbilder test.

PubMed

Melo-Silva, Lucy Leal; Pasian, Sonia Regina; Assoni, Renata de Fátima; Bonfim, Talma Alzira

2008-05-01

The object of this study is to assess informative possibilities of some technical indicators of the Test of Photos of Professions (BBT--Berufsbilder test), a projective method to clarify professional inclination, proposed by Martin Achtnich. This psychological evaluation technique is composed of 96 photos of professionals, performing various types of activities. The test subject classifies the photos into three groups: positive (agreeable), negative (disagreeable) and indifferent (neutral). Among those chosen positively, five preferences are chosen and a story is developed that includes them, an activity that is requested two times during the Vocational Guidance process: in the beginning (or middle) and at the end of the intervention. In this study, 160 stories were created by 80 youths, between 15 and 20 years of age, in public and private schools in a mid-sized Brazilian city. The stories were compared in three analytical categories: protagonist, professional conflict and resolution. The results were submitted to Wilcoxon nonparametric statistical analysis (p < .05), significant and relevant indicators of resolution being found in the process of occupational choice. This technical resource was shown, from this empirical evidence, to be promising for use in evaluation of intervention processes of Vocational Guidance.

76 FR 60022 - Endocrine Disruptor Screening Program; Weight-of-Evidence Guidance Document; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-28

... evaluate results from the battery of Tier 1 screening assays along with other scientific and technical... guidance document that requested additional detail and clarification of the following: 1. Tier 1 battery of...

Guidance for Delisting Michigan’s Great Lakes Areas of Concern

EPA Pesticide Factsheets

A useful tool for guidance in delisting Michigan’s Areas of Concern. Technical staff in the Michigan Department of Environmental Quality (MDEQ), the Michigan Department of Natural Resources (MDNR), USEPA Great Lakes National Program Office, among others.

UV DISINFECTION GUIDANCE MANUAL FOR THE ...

EPA Pesticide Factsheets

Provides technical information on selection, design and operation of UV systems; provides regulatory agencies with guidance and the necessary tools to assess UV systems at the design, start-up, and routine operation phase; provides manufacturers with the testing and performance standards for UV components and systems for treating drinking water. Provide guidance to water systems, regulators and manufacturers on UV disinfection of drinking water.

Technical Guidance from the International Safety Framework for Nuclear Power Source Applications in Outer Space for Design and Development Phases

NASA Astrophysics Data System (ADS)

Summerer, Leopold

2014-08-01

In 2009, the International Safety Framework for Nuclear Power Source Applications in Outer Space [1] has been adopted, following a multi-year process that involved all major space faring nations in the frame of the International Atomic Energy Agency and the UN Committee on the Peaceful Uses of Outer Space. The safety framework reflects an international consensus on best practices. After the older 1992 Principles Relevant to the Use of Nuclear Power Sources in Outer Space, it is the second document at UN level dedicated entirely to space nuclear power sources.This paper analyses aspects of the safety framework relevant for the design and development phases of space nuclear power sources. While early publications have started analysing the legal aspects of the safety framework, its technical guidance has not yet been subject to scholarly articles. The present paper therefore focuses on the technical guidance provided in the safety framework, in an attempt to assist engineers and practitioners to benefit from these.

Research on artistic gymnastics training guidance model

NASA Astrophysics Data System (ADS)

Luo, Lin; Sun, Xianzhong

2017-04-01

Rhythmic gymnastics training guidance model, taking into consideration the features of artistic gymnastics training, is put forward to help gymnasts identify their deficiencies and unskilled technical movements and improve their training effects. The model is built on the foundation of both physical quality indicator model and artistic gymnastics training indicator model. Physical quality indicator model composed of bodily factor, flexibility-strength factor and speed-dexterity factor delivers an objective evaluation with reference to basic sport testing data. Training indicator model, based on physical fitness indicator, helps analyze the technical movements, through which the impact from each bodily factor on technical movements is revealed. AG training guidance model, in further combination with actual training data and in comparison with the data shown in the training indicator model, helps identify the problems in trainings, and thus improve the training effect. These three models when in combined use and in comparison with historical model data can check and verify the improvement in training effect over a certain period of time.

The World Health Organization's safe abortion guidance document.

PubMed

Van Look, Paul F A; Cottingham, Jane

2013-04-01

We discuss the history of the World Health Organization's (WHO's) development of guidelines for governments on providing safe abortion services, which WHO published as Safe Abortion: Technical and Policy Guidance for Health Systems in 2003 and updated in 2012. We show how the recognition of the devastating impact of unsafe abortion on women's health and survival, the impetus of the International Conference on Population and Development and its five-year follow-up, and WHO's progressive leadership at the end of the century enabled the organization to elaborate guidance on providing safe abortion services. Guideline formulation involved extensive review of published evidence, an international technical expert meeting to review the draft document, and a protracted in-house review by senior WHO management.

76 FR 57057 - International Cooperation on Harmonisation of Technical Requirements for Registration of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-15

... Drugs in Food-Producing Animals: Comparative Metabolism Studies in Laboratory Animals; Availability...: Comparative Metabolism Studies in Laboratory Animals'' (VICH GL47). This guidance has been developed for... Metabolism and Residue Kinetics of Veterinary Drugs in Food- Producing Animals: Comparative Metabolism...

A Qualitative Assessment of Current CCF Guidance Based on a Review of Safety System Digital Implementation Changes with Evolving Technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Korsah, Kofi; Muhlheim, Michael David; Wood, Richard

The US Nuclear Regulatory Commission (NRC) is initiating a new rulemaking project to develop a digital system common-cause failure (CCF) rule. This rulemaking will review and modify or affirm the NRC's current digital system CCF policy as discussed in the Staff Requirements Memorandum to the Secretary of the Commission, Office of the NRC (SECY) 93-087, Policy, Technical, and Licensing Issues Pertaining to Evolutionary and Advanced Light Water Reactor (ALWR) Designs, and Branch Technical Position (BTP) 7-19, Guidance on Evaluation of Defense-in-Depth and Diversity in Digital Computer-Based Instrumentation and Control Systems, as well as Chapter 7, Instrumentation and Controls, in NRCmore » Regulatory Guide (NUREG)-0800, Standard Review Plan for Review of Safety Analysis Reports for Nuclear Power Plants (ML033580677). The Oak Ridge National Laboratory (ORNL) is providing technical support to the NRC staff on the CCF rulemaking, and this report is one of several providing the technical basis to inform NRC staff members. For the task described in this report, ORNL examined instrumentation and controls (I&C) technology implementations in nuclear power plants in the light of current CCF guidance. The intent was to assess whether the current position on CCF is adequate given the evolutions in digital safety system implementations and, if gaps in the guidance were found, to provide recommendations as to how these gaps could be closed.« less

IRIS Summary and Supporting Documents for Methylmercury ...

EPA Pesticide Factsheets

In January 2001, U.S. EPA finalized the guidance for methylmercury in the water quality criteria for states and authorized tribes. The links below take you to the best resources for this guidance. This final Guidance for Implementing the January 2001 Methylmercury Water Quality Criterion provides technical guidance to states and authorized tribes on how they may want to use the January 2001 fish tissue-based recommended water quality criterion for methylmercury in surface water protection programs (e.g., TMDLs, NPDES permitting). The guidance addresses questions related to water quality standards adoption (e.g., site-specific criteria, variances), assessments, monitoring, TMDLs, and NPDES permitting. The guidance consolidates existing EPA guidance where relevant to mercury.

Approval of Modified Seating Systems Initially Approved Under A Technical Standard Order

DOT National Transportation Integrated Search

1997-06-03

The Advisory Circular (AC) provides information, clarification, and procedural : guidance concerning the approval and installation of modified Technical Standard : Order (TSO) seating systems in U.S. type certificated aircraft.

Technical guidelines for environmental dredging of contaminated sediments

DOT National Transportation Integrated Search

2008-09-01

This report provides technical guidelines for evaluating : environmental dredging as a sediment remedy component. This document : supports the Contaminated Sediment Remediation Guidance for : Hazardous Waste Sites, released by the U.S. Environmental ...

77 FR 69634 - International Conference on Harmonisation; Guidance on Q11 Development and Manufacture of Drug...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-20

... Document (CTD). The guidance is intended to harmonize the scientific and technical principles relating to... sections of the CTD. A summary of changes includes the following: (1) Revisions to the introduction and...

Developing Technical Skill Assessments

ERIC Educational Resources Information Center

Hyslop, Alisha

2009-01-01

One of the biggest challenges facing the career and technical education (CTE) community as it works to implement the 2006 Perkins Act is responding to more rigorous requirements for reporting on CTE students' technical skill attainment. The U.S. Department of Education suggested in non-regulatory guidance that states and locals use the number of…

76 FR 8366 - Science Advisory Board Staff Office; Request for Nominations; SAB Environmental Justice Technical...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-14

... Nominations; SAB Environmental Justice Technical Panel AGENCY: Environmental Protection Agency (EPA). ACTION... experts to serve on the SAB Environmental Justice Technical (EJT) Panel. DATES: Nominations should be...) released the Interim Guidance on Considering Environmental Justice During the Development of an Action...

BENCHMARK DOSE TECHNICAL GUIDANCE DOCUMENT ...

EPA Pesticide Factsheets

The purpose of this document is to provide guidance for the Agency on the application of the benchmark dose approach in determining the point of departure (POD) for health effects data, whether a linear or nonlinear low dose extrapolation is used. The guidance includes discussion on computation of benchmark doses and benchmark concentrations (BMDs and BMCs) and their lower confidence limits, data requirements, dose-response analysis, and reporting requirements. This guidance is based on today's knowledge and understanding, and on experience gained in using this approach.

Local Free-Space Mapping and Path Guidance for Mobile Robots.

DTIC Science & Technology

1988-03-01

CM a CD U 00 Technical Document 1227 March 1988 Local Free- Space Mapping o and Path Guidance for Mobile Robots o William T. Gex N’% Nancy L. Campbell...TITLE (inludvSeocutCl&sas~o*) Local Free- Space Mapping and Path Guidance for Mobile Robots 12. PERSONAL AUTHOR(S) William T. Gex and Nancy L...Description of Robot System... 2 Free- Space Mapping ... 4 Map Construction ... 4 . ,12pping Examplk... 5 ’ft Sensor Unreliability... 8 % Path Guidance

"I Don't Know Where to Find the Careers Adviser … He Has Disappeared": The Impact of Changes to Careers Advice on 14-16 Year Olds in University Technical Colleges and Schools

ERIC Educational Resources Information Center

Acquah, Daniel K.; Limmer, Hayley; Malpass, Debra

2017-01-01

Recent policies in England have enacted significant changes to careers information advice and guidance (CIAG) and work-related learning (WRL). This paper offers insight into these changes from the perspective of young people studying engineering at University Technical Colleges (UTCs) as well as "comprehensive" schools. Face-to-face CIAG…

Architecture of a high-performance surgical guidance system based on C-arm cone-beam CT: software platform for technical integration and clinical translation

NASA Astrophysics Data System (ADS)

Uneri, Ali; Schafer, Sebastian; Mirota, Daniel; Nithiananthan, Sajendra; Otake, Yoshito; Reaungamornrat, Sureerat; Yoo, Jongheun; Stayman, J. Webster; Reh, Douglas; Gallia, Gary L.; Khanna, A. Jay; Hager, Gregory; Taylor, Russell H.; Kleinszig, Gerhard; Siewerdsen, Jeffrey H.

2011-03-01

Intraoperative imaging modalities are becoming more prevalent in recent years, and the need for integration of these modalities with surgical guidance is rising, creating new possibilities as well as challenges. In the context of such emerging technologies and new clinical applications, a software architecture for cone-beam CT (CBCT) guided surgery has been developed with emphasis on binding open-source surgical navigation libraries and integrating intraoperative CBCT with novel, application-specific registration and guidance technologies. The architecture design is focused on accelerating translation of task-specific technical development in a wide range of applications, including orthopaedic, head-and-neck, and thoracic surgeries. The surgical guidance system is interfaced with a prototype mobile C-arm for high-quality CBCT and through a modular software architecture, integration of different tools and devices consistent with surgical workflow in each of these applications is realized. Specific modules are developed according to the surgical task, such as: 3D-3D rigid or deformable registration of preoperative images, surgical planning data, and up-to-date CBCT images; 3D-2D registration of planning and image data in real-time fluoroscopy and/or digitally reconstructed radiographs (DRRs); compatibility with infrared, electromagnetic, and video-based trackers used individually or in hybrid arrangements; augmented overlay of image and planning data in endoscopic or in-room video; real-time "virtual fluoroscopy" computed from GPU-accelerated DRRs; and multi-modality image display. The platform aims to minimize offline data processing by exposing quantitative tools that analyze and communicate factors of geometric precision. The system was translated to preclinical phantom and cadaver studies for assessment of fiducial (FRE) and target registration error (TRE) showing sub-mm accuracy in targeting and video overlay within intraoperative CBCT. The work culminates in the development of a CBCT guidance system (reported here for the first time) that leverages the technical developments in Carm CBCT and associated technologies for realizing a high-performance system for translation to clinical studies.

International Conference on Harmonisation; guidance on Q9 Quality Risk Management; availability. Notice.

PubMed

2006-06-02

The Food and Drug Administration (FDA) is announcing the availability of a guidance entitled "Q9 Quality Risk Management."' The guidance was prepared under the auspices of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The guidance provides principles and examples of tools for quality risk management that can be applied to all aspects of pharmaceutical quality throughout the lifecycle of drug substances, drug products, and biological and biotechnological products. The guidance is intended to enable regulators and industry to make more effective and consistent risk-based decisions.

Review of Technical Studies in the United States in Support of Burnup Credit Regulatory Guidance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wagner, John C; Parks, Cecil V; Mueller, Don

2010-01-01

Taking credit for the reduction in reactivity associated with fuel depletion can enable more cost-effective, higher-density storage, transport, disposal, and reprocessing of spent nuclear fuel (SNF) while maintaining sufficient subcritical margin to establish an adequate safety basis. Consequently, there continues to be considerable interest in the United States (U.S.), as well as internationally, in the increased use of burnup credit in SNF operations, particularly related to storage, transport, and disposal of commercial SNF. This interest has motivated numerous technical studies related to the application of burnup credit, both domestically and internationally, as well as the design of SNF storage, transportmore » and disposal systems that rely on burnup credit for maintaining subcriticality. Responding to industry requests and needs, the U.S. Nuclear Regulatory Commission (NRC) initiated a burnup credit research program in 1999, with support from the Oak Ridge National Laboratory (ORNL), to develop regulatory guidance and the supporting technical bases for allowing and expanding the use of burnup credit in pressurized-water reactor SNF storage and transport applications. Although this NRC research program has not been continuous since its inception, considerable progress has been achieved in many key areas in terms of increased understanding of relevant phenomena and issues, availability of relevant information and data, and subsequently updated regulatory guidance for expanded use of burnup credit. This paper reviews technical studies performed by ORNL for the U.S. NRC burnup credit research program. Examples of topics include reactivity effects associated with reactor operating characteristics, fuel assembly characteristics, burnable absorbers, control rods, spatial burnup distributions, cooling time, and assembly misloading; methods and data for validation of isotopic composition predictions; methods and data for validation of criticality calculations; and operational issues and data related to assembly burnup confirmation. The objective of this paper is to summarize the work and significant accomplishments, with references to the technical reports and publications for complete details, and provide a useful resource to others in the burnup credit community.« less

Getting the aorta pants in place: a 'community of guidance' in the evolving practice of vascular implant surgery.

PubMed

Brattheim, Berit; Faxvaag, Arild; Tjora, Aksel

2011-09-01

The evolving nature of surgical treatments creates gaps between evidence-based guidelines and actual clinical practice.This article addresses the emerging clinical practice of the EndoVascular Aneurysm Repair (EVAR), a surgical treatment of patients with Abdominal Aortic Aneurysm (AAA). Drawing on a qualitative study across three hospitals, we identified three interplaying expertise traits: the collective, the interpersonal and the technical, each being present to promote surgical work. The evolvement of EVAR is contextualized within technical artefacts and patient characteristics, along with a joint decision approach. The intertwinement between various expertise traits and contextual factors forms a 'community of guidance', nourishing further EVAR innovation without formalized institutions, evidence, training or guidelines. However, the lack of a shared context limits the transfer of evolving knowledge across hospital boundaries.

Enabling fast charging – Introduction and overview

DOE PAGES

Michelbacher, Christopher; Ahmed, Shabbir; Bloom, Ira; ...

2017-10-23

Argonne National Laboratory (Argonne), Idaho National Laboratory (INL), and the National Renewable Energy Laboratory (NREL), with guidance from VTO, initiated this study to understand the technical, cost, infrastructure, and implementation barriers associated with high rate charging up to 350 kW.

Regulatory Issues and Challenges in Developing Seismic Source Characterizations for New Nuclear Power Plant Applications in the US

NASA Astrophysics Data System (ADS)

Fuller, C. W.; Unruh, J.; Lindvall, S.; Lettis, W.

2009-05-01

An integral component of the safety analysis for proposed nuclear power plants within the US is a probabilistic seismic hazard assessment (PSHA). Most applications currently under NRC review followed guidance provided within NRC Regulatory Guide 1.208 (RG 1.208) for developing seismic source characterizations (SSC) for their PSHA. Three key components of RG 1.208 guidance is that applicants should: (1) use existing PSHA models and SSCs accepted by the NRC as SSC as a starting point for their SSCs; (2) evaluate new information and data developed since acceptance of the starting model to determine if the model should be updated; and (3) follow guidelines set forth by the Senior Seismic Hazard Analysis Committee (SSHAC) (NUREG/CR-6372) in developing significant updates (i.e., updates should capture SSC uncertainty through representing the "center, body, and range of technical interpretations" of the informed technical community). Major motivations for following this guidance are to ensure accurate representations of hazard and regulatory stability in hazard estimates for nuclear power plants. All current applications with the NRC have used the EPRI-SOG source characterizations developed in the 1980s as their starting point model, and all applicants have followed RG 1.208 guidance in updating the EPRI- SOG model. However, there has been considerable variability in how applicants have interpreted the guidance, and thus there has been considerable variability in the methodology used in updating the SSCs. Much of the variability can be attributed to how different applicants have interpreted the implications of new data, new interpretations of new and/or old data, and new "opinions" of members of the informed technical community. For example, many applicants and the NRC have wrestled with the challenge of whether or not to update SSCs in light of new opinions or interpretations of older data put forth by one member of the technical community. This challenge has been further complicated by: (1) a given applicant's uncertainty in how to revise the EPRI-SOG model, which was developed using a process similar to that dictated by SSHAC for a level 3 or 4 study, without conducting a resource-intensive SSHAC level 3 or higher study for their respective application; and (2) a lack of guidance from the NRC on acceptable methods of demonstrating that new data, interpretations, and opinions are adequately represented within the EPRI-SOG model. Partly because of these issues, initiative was taken by the nuclear industry, NRC and DOE to develop a new base PSHA model for the central and eastern US. However, this new SSC model will not be completed for several years and does not resolve many of the fundamental regulatory and philosophical issues that have been raised during the current round of applications. To ensure regulatory stability and to provide accurate estimates of hazard for nuclear power plants, a dialog must be started between regulators and industry to resolve these issues. Two key issues that must be discussed are: (1) should new data and new interpretations or opinions of old data be treated differently in updated SSCs, and if so, how?; and (2) how can new data or interpretations developed by a small subset of the technical community be weighed against and potentially combined with a SSC model that was originally developed to capture the "center, body and range" of the technical community?

The World Health Organization’s Safe Abortion Guidance Document

PubMed Central

Van Look, Paul F. A.; Cottingham, Jane

2013-01-01

We discuss the history of the World Health Organization’s (WHO’s) development of guidelines for governments on providing safe abortion services, which WHO published as Safe Abortion: Technical and Policy Guidance for Health Systems in 2003 and updated in 2012. We show how the recognition of the devastating impact of unsafe abortion on women’s health and survival, the impetus of the International Conference on Population and Development and its five-year follow-up, and WHO’s progressive leadership at the end of the century enabled the organization to elaborate guidance on providing safe abortion services. Guideline formulation involved extensive review of published evidence, an international technical expert meeting to review the draft document, and a protracted in-house review by senior WHO management. PMID:23409886

Technical Packages in Injury and Violence Prevention to Move Evidence into Practice: Systematic Reviews and Beyond

PubMed Central

Haegerich, Tamara M.; David-Ferdon, Corinne; Noonan, Rita K.; Manns, Brian J.; Billie, Holly C.

2016-01-01

Injury and violence prevention strategies have greater potential for impact when they are based on scientific evidence. Systematic reviews of the scientific evidence can contribute key information about which policies and programs might have the greatest impact when implemented. However, systematic reviews have limitations, such as lack of implementation guidance and contextual information, that can limit the application of knowledge. “Technical packages,” developed by knowledge brokers such as the federal government, nonprofit agencies, and academic institutions, have the potential to be an efficient mechanism for making information from systematic reviews actionable. Technical packages provide information about specific evidence-based prevention strategies, along with the estimated costs and impacts, and include accompanying implementation and evaluation guidance to facilitate adoption, implementation, and performance measurement. We describe how systematic reviews can inform the development of technical packages for practitioners, provide examples of technical packages in injury and violence prevention, and explain how enhancing review methods and reporting could facilitate the use and applicability of scientific evidence. PMID:27604301

Professional technical standards in colleges and schools of pharmacy.

PubMed

Berry, Tricia M; Chichester, Clinton O; Lundquist, Lisa M; Sanoski, Cynthia A; Woodward, Donald A; Worley, Marcia M; Early, Johnnie L

2011-04-11

To determine the prevalence, characteristics, and use of professional technical standards among colleges and schools of pharmacy accredited by the Accreditation Council for Pharmacy Education (ACPE). The Web site of every college and school of pharmacy accredited by ACPE was searched to identify information regarding the availability, content, and use of technical standards and to obtain demographic information. Information was obtained from all of the 114 colleges and schools of pharmacy and 67 (59%) had technical standards in place. Common themes for technical standards were: observation; communication; motor; intellectual, conceptual, integrative and quantitative abilities; and behavioral and social attributes. Of those colleges and schools with technical standards, 61 (91%) had standards that addressed all 5 of these themes and 34 (51%) specified that the technical standards were used in their admission, progression, and graduation procedures. More than half of the colleges and schools of pharmacy examined in this study have technical standards; however, 41% have yet to develop and implement them. Colleges and schools of pharmacy looking for guidance in technical standards development could use the technical standards themes identified in this study.

Professional Technical Standards in Colleges and Schools of Pharmacy

PubMed Central

Berry, Tricia M.; Chichester, Clinton O.; Sanoski, Cynthia A.; Woodward, Donald A.; Worley, Marcia M.; Early, Johnnie L.

2011-01-01

Objective To determine the prevalence, characteristics, and use of professional technical standards among colleges and schools of pharmacy accredited by the Accreditation Council for Pharmacy Education (ACPE). Methods The Web site of every college and school of pharmacy accredited by ACPE was searched to identify information regarding the availability, content, and use of technical standards and to obtain demographic information. Results Information was obtained from all of the 114 colleges and schools of pharmacy and 67 (59%) had technical standards in place. Common themes for technical standards were: observation; communication; motor; intellectual, conceptual, integrative and quantitative abilities; and behavioral and social attributes. Of those colleges and schools with technical standards, 61 (91%) had standards that addressed all 5 of these themes and 34 (51%) specified that the technical standards were used in their admission, progression, and graduation procedures. Conclusion More than half of the colleges and schools of pharmacy examined in this study have technical standards; however, 41% have yet to develop and implement them. Colleges and schools of pharmacy looking for guidance in technical standards development could use the technical standards themes identified in this study. PMID:21655404

78 FR 72755 - Version 5 Critical Infrastructure Protection Reliability Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-03

... (e.g., thumb drives and laptop computers) that fall outside of the BES Cyber Asset definition.\\5... implementation study is part of a larger program that includes the development of guidance, outreach to industry... the goals of the implementation study include: (1) Improving industry's understanding of the technical...

Instrument and Survey Analysis Technical Report: Program Implementation Survey. Technical Report #1112

ERIC Educational Resources Information Center

Alonzo, Julie; Tindal, Gerald

2011-01-01

This technical document provides guidance to educators on the creation and interpretation of survey instruments, particularly as they relate to an analysis of program implementation. Illustrative examples are drawn from a survey of educators related to the use of the easyCBM learning system. This document includes specific sections on…

SCIENTIFIC AND TECHNICAL SOCIETIES PERTINENT TO THE EDUCATION OF TECHNICIANS. TECHNICAL EDUCATION PROGRAM SERIES NO. 7.

ERIC Educational Resources Information Center

BROOKING, WALTER J.

THIS LISTING OF SELECTED NATIONAL SCIENTIFIC AND TECHNICAL SOCIETIES WAS PUBLISHED TO ASSIST FEDERAL, STATE, AND LOCAL SCHOOL ADMINISTRATORS, SUPERVISORS, DEPARTMENT HEADS, TEACHERS, LIBRARIANS, AND GUIDANCE PERSONNEL TO UNDERSTAND BETTER THE SERVICES OF SUCH SOCIETIES AND TO PROVIDE AN EASILY ACCESSIBLE AND SCIENTIFIC GUIDE TO THEM. CHAPTER…

Space Shuttle Technical Conference, Part 2

NASA Technical Reports Server (NTRS)

Chaffee, Norman (Compiler)

1985-01-01

The retrospective presentation provides technical disciplinary focus in the following technical areas: (1) integrated avionics; (2) guidance, navigation, and control; (3) aerodynamics; (4) structures; (5) life support, environmental control, and crew station; (6) ground operations; (7) propulsion and power; (8) communications and tracking; (9) mechanics and mechanical systems; and (10) thermal and contamination environments and protection systems.

Ecological Risk Assessment Guidance for Superfund: Process for Designing and Conducting Ecological Risk Assessments - Interim Final

EPA Pesticide Factsheets

This document provides guidance to site managers and Remedial Project Managers who are legally responsible for the management of a site on how to design and conduct technically defensible ecological risk assessments for the Superfund program.

78 FR 33416 - Notification of a Public Meeting of the Science Advisory Board Environmental Justice Technical...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-04

....federalregister.gov/articles/2013/05/09/2013-11165/technical-guidance-for-assessing-environmental-justice-in... of nationally and internationally recognized scientists to serve on this panel. Additional background...

A WET TALE: TOXICITY OF COMPLEX EFFLUENTS

EPA Science Inventory

This course covers standards, regulations, policy, guidance and technical aspects of implementing the whole effluent toxicity program. The curriculum incorporates rationale and information on WET test requirements from USEPA documents, such as the Technical Support Document for W...

TIM Version 3.0 beta - Technical Description and User's Guidance

EPA Pesticide Factsheets

Provides technical information on version 3.0 of the Terrestrial Investigation Model (TIM v.3.0). Describes how TIM derives joint distributions of exposure and toxicity to calculate the risk of mortality to birds.

75 FR 18508 - International Cooperation on Harmonisation of Technical Requirements for Registration of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-12

... a framework for metabolism testing, it is important that the design of the studies remains flexible... Products (VICH); Draft Guidance for Industry on Studies to Evaluate the Metabolism and Residue Kinetics of Veterinary Drugs in Food-Producing Animals: Metabolism Study to Determine the Quantity and Identify the...

76 FR 57054 - International Cooperation on Harmonisation of Technical Requirements for Registration of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-15

... recommends a framework for metabolism testing, it is important that the design of the studies remains... Products; Guidance for Industry on Studies To Evaluate the Metabolism and Residue Kinetics of Veterinary Drugs in Food-Producing Animals: Metabolism Study To Determine the Quantity and Identify the Nature of...

Content of system design descriptions

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

A System Design Description (SDD) describes the requirements and features of a system. This standard provides guidance on the expected technical content of SDDs. The need for such a standard was recognized during efforts to develop SDDs for safety systems at DOE Hazard Category 2 nonreactor nuclear facilities. Existing guidance related to the corresponding documents in other industries is generally not suitable to meet the needs of DOE nuclear facilities. Across the DOE complex, different contractors have guidance documents, but they vary widely from site to site. While such guidance documents are valuable, no single guidance document has all themore » attributes that DOE considers important, including a reasonable degree of consistency or standardization. This standard is a consolidation of the best of the existing guidance. This standard has been developed with a technical content and level of detail intended to be most applicable to safety systems at DOE Hazard Category 2 nonreactor nuclear facilities. Notwithstanding that primary intent, this standard is recommended for other systems at such facilities, especially those that are important to achieving the programmatic mission of the facility. In addition, application of this standard should be considered for systems at other facilities, including non-nuclear facilities, on the basis that SDDs may be beneficial and cost-effective.« less

International Conference on Harmonisation; guidance on Q10 Pharmaceutical Quality System; availability. Notice.

PubMed

2009-04-08

The Food and Drug Administration (FDA) is announcing the availability of a guidance entitled "Q10 Pharmaceutical Quality System." The guidance was prepared under the auspices of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The guidance describes a model for an effective quality management system for the pharmaceutical industry, referred to as the Pharmaceutical Quality System. The guidance is intended to provide a comprehensive approach to an effective pharmaceutical quality system that is based on International Organization for Standardization (ISO) concepts, includes applicable good manufacturing practice (GMP) regulations and complements ICH guidances on "Q8 Pharmaceutical Development" and "Q9 Quality Risk Management."

US EPA GLOBAL POSITIONING SYSTEMS - TECHNICAL IMPLEMENTATION GUIDANCE

EPA Science Inventory

The U.S. EPA Geospatial Quality Council (GQC) was formed in 1998 to provide Quality Assurance guidance for the development, use, and products of geospatial activities and research. The long-term goals of the GQC are expressed in a living document, currently the EPA Geospatial Qua...

Department of Defense Intelligence Information System (DoDIIS). Instructions 2000

DTIC Science & Technology

2000-02-01

DIA, November 1993, DoDIIS Site Certifier’s Guide, SC-2610-143-93. e) DIA, June 1995, DoDIIS Security Architecture Guidance and Directions ( SAGD ), Draft...Plan S&T Scientific & Technical SAGD Security Architecture Guidance and Directions SBU Sensitive But Unclassified SCI Sensitive Compartmented

76 FR 27274 - Defense Federal Acquisition Regulation Supplement; Technical Amendments

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-11

... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Part 225 Defense Federal Acquisition Regulation Supplement; Technical Amendments AGENCY: Defense Acquisition Regulations System... Federal Acquisition Regulation Supplement (DFARS) to direct contracting officers to additional guidance on...

WHO Expert Committee on Specifications for Pharmaceutical Preparations. Fiftieth report.

PubMed

2016-01-01

The Expert Committee on Specifications for Pharmaceutical Preparations works towards clear, independent and practical standards and guidelines for the quality assurance of medicines. Standards are developed by the Committee through worldwide consultation and an international consensus-building process. The following new guidelines were adopted and recommended for use. Good pharmacopoeial practices; FIP-WHO technical guidelines: points to consider in the provision by health-care professionals of children-specific preparations that are not available as authorized products; Guidance on good manufacturing practices for biological products; Guidance on good manufacturing practices: inspection report, including Appendix 1: Model inspection report; Guidance on good data and record management practices; Good trade and distribution practices for starting materials; Guidelines on the conduct of surveys of the quality of medicines; Collaborative procedure between the World Health Organization (WHO) prequalification team and national regulatory authorities in the assessment and accelerated national registration of WHO-prequalified pharmaceutical products and vaccines; Guidance for organizations performing in vivo bioequivalence studies; and World Health Organization (WHO) general guidance on variations to multisource pharmaceutical products.

78 FR 15664 - Approval and Promulgation of Air Quality Implementation Plans; New Mexico; Interstate Transport...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-12

... technical analysis supporting New Mexico's conclusion as recommended by EPA's guidance memorandum that... modeling technical analyses are available, but EPA does not believe that modeling is necessarily required...)(2)(D)(i)(I) for the 2006 PM 2.5 NAAQS in several ways. It takes into account the technical analysis...

76 FR 4579 - Approval and Promulgation of Air Quality Implementation Plan; New Jersey and New York...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-26

... supported by an adequate technical analysis. EPA recommended the various types of information that could be...) must be supported by an adequate technical analysis. In the 2009 Guidance, EPA recommended the various...) because the State did not evaluate or demonstrate with a technical analysis that the emissions reduction...

Considerations for high occupancy vehicle (HOV) to high occupancy toll (HOT) lanes conversions guidebook.

DOT National Transportation Integrated Search

2007-06-01

The intent of this study is to explore the planning, design, and ongoing operation and maintenance of HOT facilities and to provide lessons learned and applicable technical guidance that will assist the state and local transportation planners and des...

General Drafting. Technical Manual.

ERIC Educational Resources Information Center

Department of the Army, Washington, DC.

The manual provides instructional guidance and reference material in the principles and procedures of general drafting and constitutes the primary study text for personnel in drafting as a military occupational specialty. Included is information on drafting equipment and its use; line weights, conventions and formats; lettering; engineering charts…

76 FR 57716 - Notice of Availability of a Draft Companion Manual for Executive Order 11988 Floodplain...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-16

... companion manual to provide agency-wide guidance for executing compliance with Executive Order 11988... procedures and guidance in accordance with specific sections of Executive Order 11988 and Executive Order.... ADDRESSES: Written comments should be sent to Emily Johannes, Senior Environmental Technical Advisor, NOAA...

Guidance Manual: Asbestos Operations & Maintenance Work Practices. Second Edition.

ERIC Educational Resources Information Center

National Inst. of Building Sciences, Washington, DC.

This technical manual provides detailed guidance to building owners, asbestos program managers, and operations and maintenance (O&M) workers for managing asbestos-containing materials (ACM) in buildings. The manual addresses four different types of ACM found in buildings and three different levels of precaution which may be warranted by…

Laboratory Biosafety and Biosecurity Risk Assessment Technical Guidance Document

DOE Office of Scientific and Technical Information (OSTI.GOV)

Astuto-Gribble, Lisa M; Caskey, Susan Adele

2014-07-01

The purpose of this document is threefold: 1) to describe the laboratory bio safety and biosecurity risk assessment process and its conceptual framework; 2) provide detailed guidance and suggested methodologies on how to conduct a risk assessment; and 3) present some practical risk assessment process strategies using realistic laboratory scenarios.

78 FR 39284 - Technical Guidance for Assessing Environmental Justice in Regulatory Analysis

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-01

... environmental justice assessments of its regulatory actions for years. This experience and body of work... set of questions to guide analysts in evaluating potential environmental justice concerns in EPA rules.... This guidance takes into account EPA's past experience in integrating EJ into the rulemaking process...

TIM Version 3.0 beta Technical Description and User Guide - Appendix A - User's Guidance for TIM v.3.0(beta)

EPA Pesticide Factsheets

Provides detailed guidance to the user on how to select input parameters for running the Terrestrial Investigation Model (TIM) and recommendations for default values that can be used when no chemical-specific or species-specific information are available.

Technical Guidance for Hazardous Analysis, Emergency Planning for Extremely Hazardous Substances

EPA Pesticide Factsheets

This current guide supplements NRT-1 by providing technical assistance to LEPCs to assess the lethal hazards related to potential airborne releases of extremely hazardous substances (EHSs) as designated under Section 302 of Title Ill of SARA.

ANNOTATED BIBLIOGRAPHY FOR VOCATIONAL-TECHNICAL EDUCATION, 1966.

ERIC Educational Resources Information Center

BRUNETTI, FRANK; WILLIAMS, JEROME

MORE THAN 1,000 ITEMS ARE LISTED ALPHABETICALLY WITHIN SUBJECT AREAS. THE AREAS INCLUDE AGRICULTURAL EDUCATION, ART INDUSTRIES AND TRADE, BUSINESS EDUCATION, ECONOMICS, JOB ANALYSIS, LABOR AND DEMOCRACY, MANPOWER, OCCUPATIONAL HEALTH NURSING, OCCUPATIONS, PERSONNEL MANAGEMENT, TECHNICAL EDUCATION, VOCATIONAL GUIDANCE, VOCATIONAL MATHEMATICS,…

DOE technical standards list: Department of Energy standards index

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This technical standards list (TSL) was prepared for use by personnel involved in the selection and use of US DOE technical standards and other government and non-government standards. This TSL provides listings of current DOE technical standards, non-government standards that have been adopted by DOE, other government documents in which DOE has a recorded interest, and cancelled DOE technical standards. Standards are indexed by type in the appendices to this document. Definitions of and general guidance for the use of standards are also provided.

Considerations for high occupancy vehicle (HOV) lane to high occupancy toll (HOT) lane conversions guidebook

DOT National Transportation Integrated Search

2007-06-01

The intent of this study is to explore the planning, design, and ongoing operation and maintenance of HOT facilities and to provide lessons learned and applicable technical guidance that will assist the state and local transportation planners and des...

Technical Operating Procedures for State Access Under the Oil Pollution Act of 1990

DOT National Transportation Integrated Search

1992-11-01

Technical Operating Procedures (TOPs) to be used by the National Pollution Funds : Center (NPFC) to provide guidance to Federal On-Scene Coordinators (FOSCs) and : Coast Guard Districts concerning a State Governor's request for access to the : Oil Sp...

40 CFR 300.810 - Contents of the administrative record file.

Code of Federal Regulations, 2013 CFR

2013-07-01

... determination of imminent and substantial endangerment, public health evaluations, and technical and engineering... and appropriate requirements, guidance on risk/exposure assessments, engineering handbooks, articles from technical journals, memoranda on the application of a specific regulation to a site, and memoranda...

40 CFR 300.810 - Contents of the administrative record file.

Code of Federal Regulations, 2012 CFR

2012-07-01

... determination of imminent and substantial endangerment, public health evaluations, and technical and engineering... and appropriate requirements, guidance on risk/exposure assessments, engineering handbooks, articles from technical journals, memoranda on the application of a specific regulation to a site, and memoranda...

40 CFR 300.810 - Contents of the administrative record file.

Code of Federal Regulations, 2011 CFR

2011-07-01

... determination of imminent and substantial endangerment, public health evaluations, and technical and engineering... and appropriate requirements, guidance on risk/exposure assessments, engineering handbooks, articles from technical journals, memoranda on the application of a specific regulation to a site, and memoranda...

40 CFR 300.810 - Contents of the administrative record file.

Code of Federal Regulations, 2014 CFR

2014-07-01

... determination of imminent and substantial endangerment, public health evaluations, and technical and engineering... and appropriate requirements, guidance on risk/exposure assessments, engineering handbooks, articles from technical journals, memoranda on the application of a specific regulation to a site, and memoranda...

Technical Packages in Injury and Violence Prevention to Move Evidence Into Practice: Systematic Reviews and Beyond.

PubMed

Haegerich, Tamara M; David-Ferdon, Corinne; Noonan, Rita K; Manns, Brian J; Billie, Holly C

2016-09-07

Injury and violence prevention strategies have greater potential for impact when they are based on scientific evidence. Systematic reviews of the scientific evidence can contribute key information about which policies and programs might have the greatest impact when implemented. However, systematic reviews have limitations, such as lack of implementation guidance and contextual information, that can limit the application of knowledge. "Technical packages," developed by knowledge brokers such as the federal government, nonprofit agencies, and academic institutions, have the potential to be an efficient mechanism for making information from systematic reviews actionable. Technical packages provide information about specific evidence-based prevention strategies, along with the estimated costs and impacts, and include accompanying implementation and evaluation guidance to facilitate adoption, implementation, and performance measurement. We describe how systematic reviews can inform the development of technical packages for practitioners, provide examples of technical packages in injury and violence prevention, and explain how enhancing review methods and reporting could facilitate the use and applicability of scientific evidence. © The Author(s) 2016.

75 FR 9203 - Guidance on Preparation of Market-Based Rate Filings and Electric Quarterly Reports by Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-01

... Preparation of Market-Based Rate Filings and Electric Quarterly Reports by Public Utilities; Supplemental Notice of Technical Conference February 22, 2010. As announced in the ``Notice of Technical Conference'' issued on January 28, 2010, a technical conference will be held on March 3, 2010, from 9 a.m. to 3 p.m...

U.S. ENVIRONMENTAL PROTECTION AGENCY RESEARCH AND TECHNICAL SUPPORT NEEDS RELATED TO CONCEPTUAL MODEL DEVELOPMENT FOR SUBSURFACE REACTIVE TRANSPORT MODELING OF INORGANIC CONTAMINANTS, RADIONUCLIDES, AND NUTRIENTS

EPA Science Inventory

EPA's Office of Research and Development is responsible to EPA's Office of Solid Waste to provide research and technical support for waste site closures and the development of technical guidance in support of environmental regulations and programmatic policies. ORD is also respo...

"Teaching Case": ComprehensiveCare and the Failed Implementation of an Electronic Health Records System

ERIC Educational Resources Information Center

Gomillion, David L.

2017-01-01

Administrator Jennifer Stanton attempts to adopt an Electronic Health Records system at ComprehensiveCare, a multispecialty healthcare practice. Consultants from the vendor provide guidance to the organization, but do not provide that guidance in a way that the non-technical administrator understands. The project experiences escalation of…

National Pollution Funds Center (NPFC) INSTRUCTION M5890.3: Technical Operating Procedures (TOPS) for Designation of Source Under the Oil Pollution Act of 1990

DOT National Transportation Integrated Search

1996-05-20

Manual was developed to provide guidance on "designation of source", and the : corresponding investigative requirements under the statute. It is intended as : internal guidance only, and is not intended to create any right or benefit, : substantive o...

Industrial Prep, Volume Four, Junior Year--Contents: Mathematics and Guidance.

ERIC Educational Resources Information Center

Hackensack Public Schools, NJ.

As part of a 3-year comprehensive interdisciplinary program in industrial preparation for vocational students, this 11th Grade teaching guide consists of units on technical mathematics and guidance. Designed as supportive material for related physics and English curriculums, the first four sections of Volume 4 on algebra, vectors, simple machines,…

Simulated lumbar minimally invasive surgery educational model with didactic and technical components.

PubMed

Chitale, Rohan; Ghobrial, George M; Lobel, Darlene; Harrop, James

2013-10-01

The learning and development of technical skills are paramount for neurosurgical trainees. External influences and a need for maximizing efficiency and proficiency have encouraged advancements in simulator-based learning models. To confirm the importance of establishing an educational curriculum for teaching minimally invasive techniques of pedicle screw placement using a computer-enhanced physical model of percutaneous pedicle screw placement with simultaneous didactic and technical components. A 2-hour educational curriculum was created to educate neurosurgical residents on anatomy, pathophysiology, and technical aspects associated with image-guided pedicle screw placement. Predidactic and postdidactic practical and written scores were analyzed and compared. Scores were calculated for each participant on the basis of the optimal pedicle screw starting point and trajectory for both fluoroscopy and computed tomographic navigation. Eight trainees participated in this module. Average mean scores on the written didactic test improved from 78% to 100%. The technical component scores for fluoroscopic guidance improved from 58.8 to 52.9. Technical score for computed tomography-navigated guidance also improved from 28.3 to 26.6. Didactic and technical quantitative scores with a simulator-based educational curriculum improved objectively measured resident performance. A minimally invasive spine simulation model and curriculum may serve a valuable function in the education of neurosurgical residents and outcomes for patients.

HHS guidance on synthetic DNA is the right step.

PubMed

Gronvall, Gigi Kwik

2010-12-01

Synthetic biology has advanced to the point where some pathogens can be manufactured from scratch. This technical leap has beneficent implications for medical research and vaccine design, but it also raises concerns that the technology could be used to produce a deadly pathogen for nefarious use. Addressing these concerns, the Department of Health and Human Services (HHS) released their Screening Framework Guidance for Providers of Synthetic Double-Stranded DNA on October 13, 2010. They took the right approach: The oversight framework for gene synthesis companies included in this guidance is adaptable to new technical developments and changing risks, it can be implemented immediately, it can be readily adopted by other countries, and it will cost little. Though there have been some calls to increase the regulatory controls on synthetic biology, these should be resisted. For now, at least, the oversight is appropriate to the risks.

77 FR 64970 - Biomass Research and Development Technical Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-24

... DEPARTMENT OF ENERGY Office of Energy Efficiency and Renewable Energy Biomass Research and... Biomass Research and Development Technical Advisory Committee. The Federal Advisory Committee Act (Pub. L... Meeting: To provide advice and guidance that promotes research and development leading to the production...

Technical Operating Procedures for Resource Documentation Under the Oil Pollution Act of 1990

DOT National Transportation Integrated Search

1996-06-01

Technical Operating Procedures (TOPs) for Resource Documentation under the Oil Pollution Act of 1990 (P.L.101-380) have been developed to provide guidance to users operating as, or in support of, the Federal On-Scene Coordinator(FOSC). The procedures...

76 FR 57060 - International Cooperation on Harmonisation of Technical Requirements for Registration of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-15

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0588] International Cooperation on Harmonisation of Technical Requirements for Registration of Veterinary Medicinal Products; Draft Guidance for Industry on Pharmacovigilance of Veterinary Medicinal Products: Electronic...

An Empirical Study of Cultures of Assessment in Higher Education

ERIC Educational Resources Information Center

Fuller, Matthew B.

2013-01-01

Higher education campus leaders face a complex state of affairs regarding the documentation of evidence of student learning. There is no shortage of technical guidance for conducting assessment (e.g. Allen, 2006; Bresciani, 2007; Bresciani, Zelna, & Anderson, 2004; Lui, 2011; Maki, 2010; Suskie, 2009; Walvrood & Anderson, 2010), and a…

(Computational Toxicology) A systematic evaluation of analogs and automated read-across prediction of estrogenicity: A case study using hindered phenols

EPA Science Inventory

Read-across is an important data gap filling technique used within category and analog approaches for regulatory hazard identification and risk assessment. Although much technical guidance is available that describes how to develop category/analog approaches, practical principles...

Ultrasound-Guided Intermediate Site Greater Occipital Nerve Infiltration: A Technical Feasibility Study.

PubMed

Zipfel, Jonathan; Kastler, Adrian; Tatu, Laurent; Behr, Julien; Kechidi, Rachid; Kastler, Bruno

2016-01-01

Two studies recently reported that computed tomography (CT) guided infiltration of the greater occipital nerve at its intermediate site allows a high efficacy rate with long-lasting pain relief following procedure in occipital neuralgia and in various craniofacial pain syndromes. The purpose of our study was to evaluate the technical feasibility and safety of ultrasound-guided intermediate site greater occipital nerve infiltration. Retrospective study. This study was conducted at the imaging department of a 1,409 bed university hospital. Local institutional review board approval was obtained and written consent was waived. In this retrospective study, 12 patients suffering from refractory occipital neuralgia or craniofacial pain syndromes were included between April and October 2014. They underwent a total of 21 ultrasound-guided infiltrations. Infiltration of the greater occipital nerve was performed at the intermediate site of the greater occipital nerve, at its first bend between obliqus capitis inferior and semispinalis capitis muscles with local anestetics and cortivazol. Technical success was defined as satisfactory diffusion of added iodinated contrast media in the fatty space between these muscles depicted on control CT scan. We also reported first data of immediate block test efficacy and initial clinical efficacy at 7 days, one month, and 3 months, defined by a decrease of at least 50% of visual analog scale (VAS) scores. Technical success rate was 95.24%. Patients suffered from right unilateral occipital neuralgia in 3 cases, left unilateral occipital neuralgia in 2 cases, bilateral occipital neuralgia in 2 cases, migraine in one case, cervicogenic headache in one case, tension-type headache in 2 cases, and cluster headache in one case. Block test efficacy was found in 93.3% (14/15) cases. Clinical efficacy was found in 80% of cases at 7 days, in 66.7% of cases at one month and in 60% of cases at 3 months. No major complications were noted. Some of the limitations of our study include that it represents a single institution. The low number of infiltrations included in this study, for this guidance procedure, is another bias. This ultrasound-guided infiltration technique appears to be feasible, safe, non-ionizing, and fast when targeting the greater occipital nerve in its intermediate portion. This imaging guidance modality should be used in routine clinical practice. Greater occipital nerve, infiltration, ultrasound guidance, corticosteroids, occipital neuralgia, craniofacial pain syndrome.

Ultrasound Guidance for Botulinum Neurotoxin Chemodenervation Procedures.

PubMed

Alter, Katharine E; Karp, Barbara I

2017-12-28

Injections of botulinum neurotoxins (BoNTs) are prescribed by clinicians for a variety of disorders that cause over-activity of muscles; glands; pain and other structures. Accurately targeting the structure for injection is one of the principle goals when performing BoNTs procedures. Traditionally; injections have been guided by anatomic landmarks; palpation; range of motion; electromyography or electrical stimulation. Ultrasound (US) based imaging based guidance overcomes some of the limitations of traditional techniques. US and/or US combined with traditional guidance techniques is utilized and or recommended by many expert clinicians; authors and in practice guidelines by professional academies. This article reviews the advantages and disadvantages of available guidance techniques including US as well as technical aspects of US guidance and a focused literature review related to US guidance for chemodenervation procedures including BoNTs injection.

Mixed reality ultrasound guidance system: a case study in system development and a cautionary tale.

PubMed

Ameri, Golafsoun; Baxter, John S H; Bainbridge, Daniel; Peters, Terry M; Chen, Elvis C S

2018-04-01

Real-time ultrasound has become a crucial aspect of several image-guided interventions. One of the main constraints of such an approach is the difficulty in interpretability of the limited field of view of the image, a problem that has recently been addressed using mixed reality, such as augmented reality and augmented virtuality. The growing popularity and maturity of mixed reality has led to a series of informal guidelines to direct development of new systems and to facilitate regulatory approval. However, the goals of mixed reality image guidance systems and the guidelines for their development have not been thoroughly discussed. The purpose of this paper is to identify and critically examine development guidelines in the context of a mixed reality ultrasound guidance system through a case study. A mixed reality ultrasound guidance system tailored to central line insertions was developed in close collaboration with an expert user. This system outperformed ultrasound-only guidance in a novice user study and has obtained clearance for clinical use in humans. A phantom study with 25 experienced physicians was carried out to compare the performance of the mixed reality ultrasound system against conventional ultrasound-only guidance. Despite the previous promising results, there was no statistically significant difference between the two systems. Guidelines for developing mixed reality image guidance systems cannot be applied indiscriminately. Each design decision, no matter how well justified, should be the subject of scientific and technical investigation. Iterative and small-scale evaluation can readily unearth issues and previously unknown or implicit system requirements. We recommend a wary eye in development of mixed reality ultrasound image guidance systems emphasizing small-scale iterative evaluation alongside system development. Ultimately, we recommend that the image-guided intervention community furthers and deepens this discussion into best practices in developing image-guided interventions.

76 FR 17963 - Renewal of Agency Information Collection for Application for Job Placement and Training Services...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-31

... training program, which provides vocational/technical training, related counseling, guidance, job placement... the job placement and training program, which provides vocational/technical training, related... Application for Job Placement and Training Services; Request for Comments AGENCY: Bureau of Indian Affairs...

FRAMEWORK APPROACH FOR MONITORED NATURAL ATTENUATION OF RADIONUCLIDE AND INORGANIC CONTAMINANTS IN GROUNDWATER

EPA Science Inventory

The USEPA is leading an effort to develop technical documentation that provides the policy, scientific and technical framework for assessing the viability of MNA for inorganic contaminants in ground water (hereafter referred to as the Framework Document). Initial guidance on the...

UNESCO's Guidance on Puberty and Sexual Health Education for Students Aged 9-12 Years Compared to an Upper Primary School Curriculum

ERIC Educational Resources Information Center

Goldman, Juliette D. G.

2015-01-01

Background: Children and young adolescents are reaching puberty earlier. Providing information about such changes before puberty can help them develop in a more competent and informed manner. Context and Objective: UNESCO's "International Technical Guidance on Sexuality Education" forms a comprehensive, evidence-based, authoritative…

78 FR 20116 - Draft Guidance for Industry and Food and Drug Administration Staff; Glass Syringes for Delivering...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-03

...] Draft Guidance for Industry and Food and Drug Administration Staff; Glass Syringes for Delivering Drug... and FDA staff entitled ``Glass Syringes for Delivering Drug and Biological Products: Technical... supplemental data are necessary for FDA to ensure the safe and effective use of glass syringes that comply with...

Endoscopic biliary stent insertion through specialized duodenal stent for combined malignant biliary and duodenal obstruction facilitated by stent or PTBD guidance.

PubMed

Lee, Jong Jin; Hyun, Jong Jin; Choe, Jung Wan; Lee, Dong-Won; Kim, Seung Young; Jung, Sung Woo; Jung, Young Kul; Koo, Ja Seol; Yim, Hyung Joon; Lee, Sang Woo

2017-11-01

Endoscopic stenting for combined malignant biliary and duodenal obstruction is technically demanding. However, this procedure can be facilitated when there is guidance from previously inserted stent or PTBD tube. This study aimed to evaluate the feasibility and clinical success rate of endoscopic placement of biliary self-expandable metal stent (SEMS) through duodenal SEMS in patients with combined biliary and duodenal obstruction due to inoperable or metastatic periampullary malignancy. A total of 12 patients with combined malignant biliary and duodenal stricture underwent insertion of biliary SEMS through the mesh of specialized duodenal SEMS from July 2012 to October 2016. Technical and clinical success rate, adverse events and survival after completion of SEMS insertion were evaluated. The duodenal strictures were located in the first portion of the duodenum in four patients (Type I), in the second portion in three patients (Type II), and in the third portion in five patients (Type III). Technical success rate of combined metallic stenting was 91.7%. Insertion of biliary SEMS was guided by previously inserted biliary SEMS in nine patients, plastic stent in one patient, and PTBD in two patients. Clinical success rate was 90.9%. There were no early adverse events after the procedure. Mean survival period after combined metallic stenting was 91.9 days (range: 15-245 days). Endoscopic placement of biliary SEMS through duodenal SEMS is feasible with high success rates and relatively easy when there is guidance. This method can be a good alternative for palliation in patients with combined biliary and duodenal obstruction.

The continuum of behavior guidance.

PubMed

Nelson, Travis

2013-01-01

Behavior guidance is a continuum of techniques, basic and advanced, fundamental to the provision of quality dental care for pediatric patients. This practice must be individualized, pairing the correct method of behavior guidance with each child. To select the appropriate technique, the clinician must have a thorough understanding of each aspect of the continuum and anticipate parental expectations, child temperament, and the technical procedures necessary to complete care. By effectively using techniques within the continuum of behavior guidance, a healing relationship with the family is maintained while addressing dental disease and empowering the child to receive dental treatment throughout their lifetime. Copyright © 2013 Elsevier Inc. All rights reserved.

WODA Technical Guidance on Underwater Sound from Dredging.

PubMed

Thomsen, Frank; Borsani, Fabrizio; Clarke, Douglas; de Jong, Christ; de Wit, Pim; Goethals, Fredrik; Holtkamp, Martine; Martin, Elena San; Spadaro, Philip; van Raalte, Gerard; Victor, George Yesu Vedha; Jensen, Anders

2016-01-01

The World Organization of Dredging Associations (WODA) has identified underwater sound as an environmental issue that needs further consideration. A WODA Expert Group on Underwater Sound (WEGUS) prepared a guidance paper in 2013 on dredging sound, including a summary of potential impacts on aquatic biota and advice on underwater sound monitoring procedures. The paper follows a risk-based approach and provides guidance for standardization of acoustic terminology and methods for data collection and analysis. Furthermore, the literature on dredging-related sounds and the effects of dredging sounds on marine life is surveyed and guidance on the management of dredging-related sound risks is provided.

An experimental investigation of the effects of alarm processing and display on operator performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

O`Hara, J.; Brown, W.; Hallbert, B.

1998-03-01

This paper describes a research program sponsored by the US Nuclear Regulatory Commission to address the human factors engineering (HFE) aspects of nuclear power plant alarm systems. The overall objective of the program is to develop HFE review guidance for advanced alarm systems. As part of this program, guidance has been developed based on a broad base of technical and research literature. In the course of guidance development, aspects of alarm system design for which the technical basis was insufficient to support complete guidance development were identified. The primary purpose of the research reported in this paper was to evaluatemore » the effects of three of these alarm system design characteristics on operator performance in order to contribute to the understanding of potential safety issues and to provide data to support the development of design review guidance in these areas. Three alarm system design characteristics studied were (1) alarm processing (degree of alarm reduction), (2) alarm availability (dynamic prioritization and suppression), and (3) alarm display (a dedicated tile format, a mixed tile and message list format, and a format in which alarm information is integrated into the process displays). A secondary purpose was to provide confirmatory evidence of selected alarm system guidance developed in an earlier phase of the project. The alarm characteristics were combined into eight separate experimental conditions. Six, two-person crews of professional nuclear power plant operators participated in the study. Following training, each crew completed 16 test trials which consisted of two trials in each of the eight experimental conditions (one with a low-complexity scenario and one with a high-complexity scenario). Measures of process performance, operator task performance, situation awareness, and workload were obtained. In addition, operator opinions and evaluations of the alarm processing and display conditions were collected. No deficient performance was observed in any of the experimental conditions, providing confirmatory support for many design review guidelines. The operators identified numerous strengths and weaknesses associated with individual alarm design characteristics.« less

Wyoming Career and Technical Education Policy Analysis

ERIC Educational Resources Information Center

MPR Associates, Inc., 2009

2009-01-01

This policy analysis was produced for the Wyoming Department of Administration and Information by MPR Associates, Inc. Its purpose was to examine federal and state policy related to career and technical education (CTE) to determine whether existing policy (in the form of statutes, rules, regulations, and guidance) could either promote or impede…

Terrestrial Ecological Unit Inventory technical guide

Treesearch

E. Winthers; D. Fallon; J. Haglund; T. DeMeo; G. Nowacki; D. Tart; M. Ferwerda; G. Robertson; A. Gallegos; A. Rorick; D. T. Cleland; W. Robbie

2005-01-01

The purpose of this technical guide is to provide specific direction and guidance for conducting Terrestrial Ecological Unit Inventory (TEUI) at the landscape and land-unit scales. TEUI seeks to classify ecological types and map terrestrial ecological units (TEUs) to a consistent standard throughout National Forest System lands. The objectives, policies, and...

Physically Healthy and Ready to Learn. Technical Assistance Paper No. 1

ERIC Educational Resources Information Center

US Department of Health and Human Services, Head Start Bureau, 2006

2006-01-01

This Technical Assistance Paper offers guidance to programs regarding the implementation of the "Head Start Program Performance Standards" on child health and developmental services, child health and safety, and child nutrition. The paper examines how physical health influences children's development and how child health and development…

Engineering Technology Careers; Career Guidance Information for Engineering Technicians. Publication No. 1065.

ERIC Educational Resources Information Center

National Council of Technical Schools, Washington, DC.

Prepared by the National Council of Technical Schools, this reference may be used by prospective students , their parents, and counselors in learning the philosophy and objectives, historical background, and present status of technical schools and career opportunities as a technician. Career opportunities included are: (1) Aerospace/Aviation…

Existing School Buildings: Incremental Seismic Retrofit Opportunities.

ERIC Educational Resources Information Center

Federal Emergency Management Agency, Washington, DC.

The intent of this document is to provide technical guidance to school district facility managers for linking specific incremental seismic retrofit opportunities to specific maintenance and capital improvement projects. The linkages are based on logical affinities, such as technical fit, location of the work within the building, cost saving…

Women and Technical Professions. Leonardo da Vinci Series: Good Practices.

ERIC Educational Resources Information Center

Commission of the European Communities, Brussels (Belgium). Directorate-General for Education and Culture.

This document profiles programs for women in technical professions that are offered through the European Commission's Leonardo da Vinci program. The following programs are profiled: (1) Artemis and Diana (vocational guidance programs to help direct girls toward technology-related careers); (2) CEEWIT (an Internet-based information and…

2015-2016 Florida Adult Education Assessment Technical Assistance Paper

ERIC Educational Resources Information Center

Florida Department of Education, 2016

2016-01-01

This technical assistance paper provides guidance to individuals with test administration responsibilities in adult education programs. These policies apply to the approved assessments that programs may use to report educational gains in compliance with the National Reporting System (NRS) requirements. The NRS is the accountability system for the…

2016-2017 Florida Adult Education Assessment Technical Assistance Paper

ERIC Educational Resources Information Center

Florida Department of Education, 2017

2017-01-01

This technical assistance paper provides guidance to individuals with test administration responsibilities in adult education programs. These policies apply to the approved assessments that programs may use to report educational gains in compliance with the National Reporting System (NRS) requirements. The NRS is the accountability system for the…

School Pesticide Use Reduction: Where There's a Will There's a Way.

ERIC Educational Resources Information Center

Riley, Becky

1994-01-01

This article presents case studies in which parents and school employees took action to reduce school pesticide use. Advice is given on the use of local and state legislation, regulation, and guidance, and where to turn for financial material, technical, and political support. Contains eight references to videos and books. (LZ)

Case Study: POLYTECH High School, Woodside, Delaware.

ERIC Educational Resources Information Center

Southern Regional Education Board, Atlanta, GA.

POLYTECH High School in Woodside, Delaware, has gone from being among the worst schools in the High Schools That Work (HSTW) network to among the best. Polytech, which is now a full-time technical high school, has improved its programs and outcomes by implementing a series of organizational, curriculum, teaching, guidance, and leadership changes,…

Study Guide for Carpet Laying [and Instructor's Key]. A Resource Guide for Industrial Cooperative Training Programs. V&TECC Curriculum Guide.

ERIC Educational Resources Information Center

Duenk, Lester G.; And Others

This study guide was prepared to aid industrial cooperative training coordinators in the technical training phase of the carpet laying training program. The guide begins with a section related to carpet laying career guidance. Specific topics in the section include status of the occupation, working conditions, salary, qualifications, and future…

Study of Synthetic Vision Systems (SVS) and Velocity-vector Based Command Augmentation System (V-CAS) on Pilot Performance

NASA Technical Reports Server (NTRS)

Liu, Dahai; Goodrich, Ken; Peak, Bob

2006-01-01

This study investigated the effects of synthetic vision system (SVS) concepts and advanced flight controls on single pilot performance (SPP). Specifically, we evaluated the benefits and interactions of two levels of terrain portrayal, guidance symbology, and control-system response type on SPP in the context of lower-landing minima (LLM) approaches. Performance measures consisted of flight technical error (FTE) and pilot perceived workload. In this study, pilot rating, control type, and guidance symbology were not found to significantly affect FTE or workload. It is likely that transfer from prior experience, limited scope of the evaluation task, specific implementation limitations, and limited sample size were major factors in obtaining these results.

Standards for Lithotripter Performance

NASA Astrophysics Data System (ADS)

Schultheiss, Reiner; Doerffel, Michael

2008-09-01

Standards for lithotripsy have been developed by the International Electrotechnical Commission (IEC) and the FDA. In addition to the existing regulations and norms for the manufacturers, special standards were developed to address a treatment method developed in the early 1980's using extracorporeal shock waves. Initially, the FDA regulated the premarket approval process for lithotripters as a Class III device but reclassified lithotripters in 2000 to a Class II device. The corresponding guidance document for showing the substantial equivalence of new devices with predicate devices will be described in detail. The FDA guidance document is very useful in helping device manufacturers: (i) develop technical performance testing for a shock wave lithotripter within the parameters of an FDA submission, and (ii) conduct clinical performance testing via at least one clinical confirmation study with a small number of subjects. Unfortunately although the submitted data are available at the FDA they are not available in the marketplace and this causes difficulties for physicians in deciding which device to use. The results of the technical performance testing of the LithoGold™ are provided.

Considerations for Developing State Policy and Guidance on Inclusion of Children with Disabilities in Early Childhood Programs

ERIC Educational Resources Information Center

Cate, D.; Dell, P.; Thompson, V.

2017-01-01

The Early Childhood Technical Assistance Center created this resource based on the "U. S. Department of Health and Human Services and the U. S. Department of Education Policy Statement on Inclusion of Children with Disabilities in Early Childhood Programs." It is intended as a tool for States to develop policy/guidance in order to…

Toward a "Common Definition of English Learner": Guidance for States and State Assessment Consortia in Defining and Addressing Policy and Technical Issues and Options

ERIC Educational Resources Information Center

Linquanti, Robert; Cook, H. Gary

2013-01-01

States participating in the four federally-funded assessment consortia are required to establish a "common definition of English Learner." This includes the two Race to the Top academic assessment consortia and the two Enhanced Assessment Grant English language proficiency (ELP) assessment consortia. This paper provides guidance that…

Hurricane Season Public Health Preparedness, Response, and Recovery Guidance for Health Care Providers, Response and Recovery Workers, and Affected Communities - CDC, 2017.

PubMed

2017-09-22

CDC and the Agency for Toxic Substances and Disease Registry (ATSDR) have guidance and technical materials available in both English and Spanish to help communities prepare for hurricanes and floods (Table 1). To help protect the health and safety of the public, responders, and clean-up workers during response and recovery operations from hurricanes and floods, CDC and ATSDR have developed public health guidance and other resources; many are available in both English and Spanish (Table 2).

Underground Injection Control (UIC)

EPA Pesticide Factsheets

Provide information on: individual injection well classes; regulations specific to each well class; technical guidance; compliance assistance; federal, state, and tribal/territory roles and responsibilities.

SEE Action Guide for States: Guidance on Establishing and Maintaining Technical Reference Manuals for Energy Efficiency Measures

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2017-06-01

The goal of this guide is to support the development, maintenance, and use of accurate and reliable Technical Reference Manuals (TRMs). TRMs provide information primarily used for estimating the energy and demand savings of end-use energy efficiency measures associated with utility customer-funded efficiency programs.

Technical Operating Procedures for Providing Funding to Natural Resource Trustees to Conduct an Initiation of Assessment of Natural Resource Damages Under the Oil Pollution Act of 1990

DOT National Transportation Integrated Search

1996-06-01

Technical Operating Procedures (TOPS) for Providing Funding to Natural Resources : Trustees To Conduct An Initiation of Assessment of Natural Resource Damages : under the Oil Pollution Act of 1990 have been developed to provide guidance on : funding ...

DEVELOPING A FRAMEWORK FOR PERFORMANCE MONITORING TO ASSESS THE USE OF MONITORED NATURAL ATTENUATION FOR REMEDIATION OF INORGANIC CONTAMINANTS IN GROUND WATER

EPA Science Inventory

The USEPA is leading an effort to develop technical documentation that provides the policy, scientific and technical framework for assessing the viability of MNA for inorganic contaminants in ground water (hereafter referred to as the Framework Document). Initial guidance on the...

Value Engineering. Technical Manual. School Facilities Development Procedures Manual.

ERIC Educational Resources Information Center

Washington Office of the State Superintendent of Public Instruction, Olympia.

Value Engineering (VE) is a cost-optimizing technique used to analyze design quality and cost-effectiveness. The application of VE procedures to the design and construction of school facilities has been adopted by the state of Washington. This technical manual provides guidance in developing the scope and applicability of VE to school projects; in…

Recent Experiences of the NASA Engineering and Safety Center (NESC) Guidance Navigation and Control (GN and C) Technical Discipline Team (TDT)

NASA Technical Reports Server (NTRS)

Dennehy, Cornelius J.

2011-01-01

The NASA Engineering and Safety Center (NESC) is an independently funded NASA Program whose dedicated team of technical experts provides objective engineering and safety assessments of critical, high risk projects. NESC's strength is rooted in the diverse perspectives and broad knowledge base that add value to its products, affording customers a responsive, alternate path for assessing and preventing technical problems while protecting vital human and national resources. The Guidance Navigation and Control (GN&C) Technical Discipline Team (TDT) is one of fifteen such discipline-focused teams within the NESC organization. The TDT membership is composed of GN&C specialists from across NASA and its partner organizations in other government agencies, industry, national laboratories, and universities. This paper will briefly define the vision, mission, and purpose of the NESC organization. The role of the GN&C TDT will then be described in detail along with an overview of how this team operates and engages in its objective engineering and safety assessments of critical NASA.

Technical Guidance for Assessing Environmental Justice in ...

EPA Pesticide Factsheets

The Technical Guidance for Assessing Environmental Justice in Regulatory Analysis (also referred to as the Environmental Justice Technical Guidance or EJTG) is intended for use by Agency analysts, including risk assessors, economists, and other analytic staff that conduct analyses to evaluate EJ concerns in the context of regulatory actions. Senior EPA managers and decision makers also may find this document useful to understand analytic expectations and to ensure that EJ concerns are appropriately considered in the development of analyses to support regulatory actions under EPA’s action development process. Specifically, the document outlines approaches and methods to help Agency analysts evaluate EJ concerns. The document provides overarching direction to analysts by outlining a series of questions that will ensure the decision maker has appropriate information about baseline risks across population groups, and how those risks are distributed under the options being considered. In addition, the document provides a set of recommendations and requirements as well as best practices for use in analyzing and reporting results from consideration of EJ concerns. These principles will help ensure consistency, quality, and transparency across regulatory actions, while allowing for flexibility needed across different regulatory actions. The purpose of the EJTG is ensure consistency, quality, and transparency in considering environmental justice, while allowing f

78 FR 22269 - International Conference on Harmonisation; Draft Guidance on M7 Assessment and Control of DNA...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-15

...The Food and Drug Administration (FDA) is announcing the availability of a draft guidance entitled ``M7 Assessment and Control of DNA Reactive (Mutagenic) Impurities in Pharmaceuticals to Limit Potential Carcinogenic Risk.'' The draft guidance was prepared under the auspices of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The draft guidance emphasizes considerations of both safety and quality risk management in establishing levels of mutagenic impurities that are expected to pose negligible carcinogenic risk. It outlines recommendations for assessment and control of mutagenic impurities that reside or are reasonably expected to reside in a final drug substance or product, taking into consideration the intended conditions of human use. The draft guidance is intended to provide guidance for new drug substances and new drug products during their clinical development and subsequent applications for marketing.

7 CFR 1465.2 - Administration.

Code of Federal Regulations, 2010 CFR

2010-01-01

... leadership for AMA; (2) Establish policies, procedures, priorities, and guidance for implementation; (3... and contracts with selected participants; (6) Provide technical leadership for implementation, quality...

7 CFR 1465.2 - Administration.

Code of Federal Regulations, 2011 CFR

2011-01-01

... leadership for AMA; (2) Establish policies, procedures, priorities, and guidance for implementation; (3... and contracts with selected participants; (6) Provide technical leadership for implementation, quality...

7 CFR 1465.2 - Administration.

Code of Federal Regulations, 2014 CFR

2014-01-01

... leadership for AMA; (2) Establish policies, procedures, priorities, and guidance for implementation; (3... and contracts with selected participants; (6) Provide technical leadership for implementation, quality...

7 CFR 1465.2 - Administration.

Code of Federal Regulations, 2012 CFR

2012-01-01

... leadership for AMA; (2) Establish policies, procedures, priorities, and guidance for implementation; (3... and contracts with selected participants; (6) Provide technical leadership for implementation, quality...

7 CFR 1465.2 - Administration.

Code of Federal Regulations, 2013 CFR

2013-01-01

... leadership for AMA; (2) Establish policies, procedures, priorities, and guidance for implementation; (3... and contracts with selected participants; (6) Provide technical leadership for implementation, quality...

The Influence of Career-Focused Education on Student Career Planning and Development: A Comparison of CTE and Non-CTE Students

ERIC Educational Resources Information Center

Mobley, Catherine; Sharp, Julia L.; Hammond, Cathy; Withington, Cairen; Stipanovic, Natalie

2017-01-01

Our study is part of a broader longitudinal study of a state-mandated career-focused school reform policy. We investigate whether career and technical education (CTE) and non-CTE students differed in interactions with guidance counselors, level of participation in career planning and development, and beliefs about the relevance of having a career…

Space station automation study. Volume 1: Executive summary. Autonomous systems and assembly

NASA Technical Reports Server (NTRS)

1984-01-01

The space station automation study (SSAS) was to develop informed technical guidance for NASA personnel in the use of autonomy and autonomous systems to implement space station functions. The initial step taken by NASA in organizing the SSAS was to form and convene a panel of recognized expert technologists in automation, space sciences and aerospace engineering to produce a space station automation plan.

Support increased adoption of green infrastructure into community stormwater management plans and watershed sustainability goals: Information and guidance through community partnerships

EPA Science Inventory

This project will provide technical assistance to support implementation of GI in U.S. communities and information on best practices for GI approaches that protect ground water supplies. Case studies that can be more broadly applied to other communities will be conducted. The pro...

Air Force Technical Objective Document FY 87

DTIC Science & Technology

1985-12-01

Air Force Systems Command Edwards Air Force Base. Cal ifornia 93523-5000 NOTICES THIS DOCUMENT IS FOR INFORMATION AND GUIDANCE ONL Y This...acquisition of Air Foree weapon systems . Each Air Foree laboratory annually formulates Q Research and Technology (R& T) Pion in response to available...guidance based on USAF requirements, the identification of scientific and technological opportunities, and the needs of present and projected systems

NASA Risk Management Handbook. Version 1.0

NASA Technical Reports Server (NTRS)

Dezfuli, Homayoon; Benjamin, Allan; Everett, Christopher; Maggio, Gaspare; Stamatelatos, Michael; Youngblood, Robert; Guarro, Sergio; Rutledge, Peter; Sherrard, James; Smith, Curtis;

Academic & Technical Skills + Life/Work Skills + Career Information & Guidance = Success in Career Building.

ERIC Educational Resources Information Center

Jarvis, Phillip S.

There has been a renaissance in the thinking about career development. It is becoming accepted that information is not enough; in addition to academic and technical skills, youth and adults need to learn life/work designing and building skills to become healthy, productive, and self-reliant citizens. Despite the fact that Canadian students have…

Reprint of: environmental information for military planning.

PubMed

Doherty, Victoria; Croft, Darryl; Knight, Ashley

2013-11-01

A study was conducted to consider the implications of presenting Environmental Information (EI; information on current environmental features including weather, topography and visibility maps) for military planning to the growing audience of non-technical users; to provide guidance for ensuring usability and for development of a suitable EI interface, and to produce an EI concept interface mock-up to demonstrate initial design ideas. Knowledge was elicited from current EI users and providers regarding anticipated use of EI by non-specialists. This was combined with human factors and cognition expertise to produce guidance for data usability and development of an EI interface. A simple mock-up of an EI concept interface was developed. Recommendations for further development were made including application of the guidance derived, identification of a user test-bed and development of business processes. Copyright © 2012 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Environmental information for military planning.

PubMed

Doherty, Victoria; Croft, Darryl; Knight, Ashley

2013-07-01

A study was conducted to consider the implications of presenting Environmental Information (EI; information on current environmental features including weather, topography and visibility maps) for military planning to the growing audience of non-technical users; to provide guidance for ensuring usability and for development of a suitable EI interface, and to produce an EI concept interface mock-up to demonstrate initial design ideas. Knowledge was elicited from current EI users and providers regarding anticipated use of EI by non-specialists. This was combined with human factors and cognition expertise to produce guidance for data usability and development of an EI interface. A simple mock-up of an EI concept interface was developed. Recommendations for further development were made including application of the guidance derived, identification of a user test-bed and development of business processes. Copyright © 2012 Elsevier Ltd and The Ergonomics Society. All rights reserved.

AACE: an innovative partnership to enhance aircraft safety

NASA Astrophysics Data System (ADS)

Shurtleff, William W.

1999-01-01

The Federal Aviation Administration established the Airworthiness Assurance Center of Excellence (AACE) in September 1997, through a cooperative agreement grant with Iowa State University (ISU) and The Ohio State University (OSU). A technical support contract with the Center is now in place as well. Initially the Center has five areas of concentration supporting advances in airworthiness assurance. These are 1. Maintenance, inspection, and repair, 2. Propulsion and fuel systems safety, 3. Crashworthiness, 4. Advanced materials, and 5. Landing gear systems performance and safety. AACE has nine core members who provide guidance to the Program Management Office at ISU/OSU through a Board of Directors. The core members are: Arizona State University, Iowa State University, Northwestern University, The Ohio State University, University of Dayton, University of Maryland, University of California - Los Angeles, Wichita State University, and Sandia National Laboratories. The organization also includes numerous academic affiliates, industry partners, government laboratories and other organizations. The Center now has over thirty technical projects supporting technical advances in airworthiness assurance. All these projects have industry guidance and support. This paper discusses the current technical program of the center and the highlights of the five-year plan for technical work. Also included is a description of the factors that make the Center an innovative partnership to promote aircraft safety.

77 FR 36273 - Public Meeting on Draft Permitting Guidance for Oil and Gas Hydraulic Fracturing Activities Using...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-18

...The Environmental Protection Agency (EPA or agency) is announcing a public meeting to discuss draft permitting guidance the agency has developed on the use of diesel fuels in oil and gas hydraulic fracturing and to solicit input during the public comment period. The meeting is open to all interested parties. The agency requests input on the following technical aspects of the draft permitting guidance: Diesel fuels description; diesel fuels usage information; permit duration and well closure; area of review; information submitted with the permit application; and monitoring.

Technical Guidance for Title V Permitting of Printing Facilities

EPA Pesticide Factsheets

This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Guidance for Using Formal Methods in a Certification Context

NASA Technical Reports Server (NTRS)

Brown, Duncan; Delseny, Herve; Hayhurst, Kelly; Wiels, Virginie

2010-01-01

This paper discusses some of the challenges to using formal methods in a certification context and describes the effort by the Formal Methods Subgroup of RTCA SC-205/EUROCAE WG-71 to propose guidance to make the use of formal methods a recognized approach. This guidance, expected to take the form of a Formal Methods Technical Supplement to DO-178C/ED-12C, is described, including the activities that are needed when using formal methods, new or modified objectives with respect to the core DO-178C/ED-12C document, and evidence needed for meeting those objectives.

Implementation Plan for Qualification of Sodium-Cooled Fast Reactor Technology Information

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moe, Wayne; Honma, George

This document identifies and discusses implementation elements that can be used to facilitate consistent and systematic evaluation processes relating to quality attributes of technical information (with focus on SFR technology) that will be used to support licensing of advanced reactor designs. Information may include, but is not limited to, design documents for SFRs, research-and-development (R&D) data and associated documents, test plans and associated protocols, operations and test data, international research data, technical reports, and information associated with past U.S. Nuclear Regulatory Commission (NRC) reviews of SFR designs. The approach for determining acceptability of test data, analysis, and/or other technical informationmore » is based on guidance provided in INL/EXT-15-35805, “Guidance on Evaluating Historic Technology Information for Use in Advanced Reactor Licensing.” The implementation plan can be adopted into a working procedure at each of the national laboratories performing data qualification, or by applicants seeking future license application for advanced reactor technology.« less

Institute for Guidance, Counseling, Administrative, Supervisory and Teaching Personnel in Vocational Programs for Chicano Students at the Secondary or Post-Secondary School Level. Final Report.

ERIC Educational Resources Information Center

Guerrero, Adalberto; Arellano, Albert

The goal of the project was to provide educational and guidance personnel in vocational and technical fields with new perspectives relating to teaching and counseling Mexican-American students. A two-week institute was held in June, 1973 at the University of Arizona for counselors, administrators, teachers, and student representatives of high…

Technical Note: Thoracic duct embolization for treatment of chylothorax: A novel guidance technique for puncture using combined MRI and fluoroscopy.

PubMed

Praveen, Alampath; Sreekumar, Karumathil Pullara; Nazar, Puthukudiyil Kader; Moorthy, Srikanth

2012-04-01

Thoracic duct embolization (TDE) is an established radiological interventional procedure for thoracic duct injuries. Traditionally, it is done under fluoroscopic guidance after opacifying the thoracic duct with bipedal lymphangiography. We describe our experience in usinga heavily T2W sequence for guiding thoracic duct puncture and direct injection of glue through the puncture needle without cannulating the duct.

Combined ultrasound and fluoroscopic guidance for radiofrequency ablation of the obturator nerve for intractable cancer-associated hip pain.

PubMed

Stone, Jonathan; Matchett, Gerald

2014-01-01

Management of pain from skeletal metastases is notoriously difficult. Case reports and case series have described radiofrequency ablation of the obturator nerve branches to the femoral head for treatment of intractable hip pain. Ablation of the obturator branches to the femoral head is technically difficult because of bony and vascular anatomy, including close proximity of the femoral vessels. Here we present the case of a 79-year-old woman with intractable right hip pain and inability to ambulate secondary to metastatic non-small cell lung cancer in the femoral head and acetabulum, treated with thermal radiofrequency ablation of the obturator and femoral nerve branches to the femoral head. Ablation of the obturator nerve was done via anterior placement of the radiofrequency needle under combined ultrasound and fluoroscopic guidance, passing the radiofrequency needle between the femoral artery and femoral vein. Real-time ultrasound guidance was used to avoid vascular puncture. Thermal radiofrequency ablation resulted in sustained pain relief, and resumption in the ability of the patient to ambulate. From this case we suggest that an anterior approach to the obturator nerve branches to the femoral head may be technically feasible using combined ultrasound and fluoroscopic guidance to avoid vascular puncture.

Human-system Interfaces to Automatic Systems: Review Guidance and Technical Basis

DOE Office of Scientific and Technical Information (OSTI.GOV)

OHara, J.M.; Higgins, J.C.

Automation has become ubiquitous in modern complex systems and commercial nuclear power plants are no exception. Beyond the control of plant functions and systems, automation is applied to a wide range of additional functions including monitoring and detection, situation assessment, response planning, response implementation, and interface management. Automation has become a 'team player' supporting plant personnel in nearly all aspects of plant operation. In light of the increasing use and importance of automation in new and future plants, guidance is needed to enable the NRC staff to conduct safety reviews of the human factors engineering (HFE) aspects of modern automation.more » The objective of the research described in this report was to develop guidance for reviewing the operator's interface with automation. We first developed a characterization of the important HFE aspects of automation based on how it is implemented in current systems. The characterization included five dimensions: Level of automation, function of automation, modes of automation, flexibility of allocation, and reliability of automation. Next, we reviewed literature pertaining to the effects of these aspects of automation on human performance and the design of human-system interfaces (HSIs) for automation. Then, we used the technical basis established by the literature to develop design review guidance. The guidance is divided into the following seven topics: Automation displays, interaction and control, automation modes, automation levels, adaptive automation, error tolerance and failure management, and HSI integration. In addition, we identified insights into the automaton design process, operator training, and operations.« less

Technical Aspects of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: CHEST Guideline and Expert Panel Report.

PubMed

Wahidi, Momen M; Herth, Felix; Yasufuku, Kazuhiro; Shepherd, Ray Wesley; Yarmus, Lonny; Chawla, Mohit; Lamb, Carla; Casey, Kenneth R; Patel, Sheena; Silvestri, Gerard A; Feller-Kopman, David J

2016-03-01

Endobronchial ultrasound (EBUS) was introduced in the last decade, enabling real-time guidance of transbronchial needle aspiration (TBNA) of mediastinal and hilar structures and parabronchial lung masses. The many publications produced about EBUS-TBNA have led to a better understanding of the performance characteristics of this procedure. The goal of this document was to examine the current literature on the technical aspects of EBUS-TBNA as they relate to patient, technology, and proceduralist factors to provide evidence-based and expert guidance to clinicians. Rigorous methodology has been applied to provide a trustworthy evidence-based guideline and expert panel report. A group of approved panelists developed key clinical questions by using the PICO (population, intervention, comparator, and outcome) format that addressed specific topics on the technical aspects of EBUS-TBNA. MEDLINE (via PubMed) and the Cochrane Library were systematically searched for relevant literature, which was supplemented by manual searches. References were screened for inclusion, and well-recognized document evaluation tools were used to assess the quality of included studies, to extract meaningful data, and to grade the level of evidence to support each recommendation or suggestion. Our systematic review and critical analysis of the literature on 15 PICO questions related to the technical aspects of EBUS-TBNA resulted in 12 statements: 7 evidence-based graded recommendations and 5 ungraded consensus-based statements. Three questions did not have sufficient evidence to generate a statement. Evidence on the technical aspects of EBUS-TBNA varies in strength but is satisfactory in certain areas to guide clinicians on the best conditions to perform EBUS-guided tissue sampling. Additional research is needed to enhance our knowledge regarding the optimal performance of this effective procedure. Copyright © 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

Testing REACH draft technical guidance notes for conducting chemical safety assessments-the experience of a downstream user of a preparation.

PubMed

Gade, Anne Lill; Ovrebø, Steinar; Hylland, Ketil

2008-07-01

The goal of REACH is the safe use of chemicals. This study examines the efficiency and usefulness of two draft technical guidance notes in the REACH Interim Project 3.2-2 for the development of the chemical safety report and exposure scenarios. A case study was carried out for a paint system for protection of structural steel. The focuses of the study were risk assessment of preparations based on Derived No Effect Level (DNEL) and Predicted No Effect Concentrations (PNEC) and on effective and accurate communication in the supply chain. Exposure scenarios and generic descriptions of uses, risk management measures, and exposure determinants were developed. The study showed that communication formats, software tools, and guidelines for chemical risk assessment need further adjustment to preparations and real-life situations. Web platforms may simplify such communication. The downstream formulator needs basic substance data from the substance manufacturer during the pre-registration phase to develop exposure scenarios for preparations. Default values need to be communicated in the supply chain because these were critical for the derivation of applicable risk management demands. The current guidelines which rely on the available toxicological knowledge are insufficient to advise downstream users on how to develop exposure scenarios for preparations.

Landfills

EPA Pesticide Factsheets

To provide information on landfills, including laws/regulations, and technical guidance on municipal solid waste, hazardous waste, industrial, PCBs, and construction and debris landfills. To provide resources for owners and operators of landfills.

Producing Scientific and Strategic Guidance for California's Department of Water Resources: The Climate Change Technical Advisory Group

NASA Astrophysics Data System (ADS)

Gyakum, J. R.; Austin, B. N.; Curtis, D. C.; Anderson, M.; Alpert, H.; Young, S.; Herson, A.; Schwarz, A.; Kavvas, M. L.; Langridge, R.; Lynn, E.; Anderson, J.; Redmond, K. T.; Dettinger, M. D.; Correa, M.; Franco, G.; Cayan, D.; Georgakakos, K.

2015-12-01

Diverse areas of expertise are needed to describe and assess a changing climate and provide guidance for the agency that runs the largest state-built, multi-purpose water project in the U.S. California's State Water Project provides: drinking water for more than 25 million people, flood control, power generation, recreation, fish and wildlife protection, and water quality improvements. Hydrologic impacts under a changing climate include rising seas, reduced ratio of snow to rain, earlier snowmelt and higher temperatures; all of which are being detected. To improve the scientific basis for decisions and enhance the consistency of climate change approaches, the California Department of Water Resources (DWR) empaneled a Climate Change Technical Advisory Group (CCTAG) for guidance on the scientific aspects of climate change, its impacts on water resources, the use and creation of planning approaches and analytical tools, and the development of adaptation responses. To carry out DWR's mission, incorporation of climate change into DWR's planning, projects, and other activities must be consistent, science-based, and continually improved through an iterative process. Hydrologists, academicians, modelers, planners, lawyers and practitioners convened regularly to tackle these complicated issues in water management policy, including climate change impacts on extreme events. Actions taken in response to the CCTAG recommendations will move California toward more sustainable management of water and related resources. DWR will release a technical report of CCTAG guidance and perspectives in 2015. The process to convene, collaborate and distribute the findings of this CCTAG will be the focus of this presentation. An academician and water resources practitioner will share their perspectives on the processes driving CCTAG's work.

U.S. Army weapon systems human-computer interface style guide. Version 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Avery, L.W.; O`Mara, P.A.; Shepard, A.P.

1997-12-31

A stated goal of the US Army has been the standardization of the human computer interfaces (HCIs) of its system. Some of the tools being used to accomplish this standardization are HCI design guidelines and style guides. Currently, the Army is employing a number of HCI design guidance documents. While these style guides provide good guidance for the command, control, communications, computers, and intelligence (C4I) domain, they do not necessarily represent the more unique requirements of the Army`s real time and near-real time (RT/NRT) weapon systems. The Office of the Director of Information for Command, Control, Communications, and Computers (DISC4),more » in conjunction with the Weapon Systems Technical Architecture Working Group (WSTAWG), recognized this need as part of their activities to revise the Army Technical Architecture (ATA), now termed the Joint Technical Architecture-Army (JTA-A). To address this need, DISC4 tasked the Pacific Northwest National Laboratory (PNNL) to develop an Army weapon systems unique HCI style guide, which resulted in the US Army Weapon Systems Human-Computer Interface (WSHCI) Style Guide Version 1. Based on feedback from the user community, DISC4 further tasked PNNL to revise Version 1 and publish Version 2. The intent was to update some of the research and incorporate some enhancements. This document provides that revision. The purpose of this document is to provide HCI design guidance for the RT/NRT Army system domain across the weapon systems subdomains of ground, aviation, missile, and soldier systems. Each subdomain should customize and extend this guidance by developing their domain-specific style guides, which will be used to guide the development of future systems within their subdomains.« less

Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Part 3: Endoscopic computer-assisted electromagnetic navigation and ultrasonography as technical adjuvants for shunt placement.

PubMed

Flannery, Ann Marie; Duhaime, Ann-Christine; Tamber, Mandeep S; Kemp, Joanna

2014-11-01

This systematic review was undertaken to answer the following question: Do technical adjuvants such as ventricular endoscopic placement, computer-assisted electromagnetic guidance, or ultrasound guidance improve ventricular shunt function and survival? The US National Library of Medicine PubMed/MEDLINE database and the Cochrane Database of Systematic Reviews were queried using MeSH headings and key words specifically chosen to identify published articles detailing the use of cerebrospinal fluid shunts for the treatment of pediatric hydrocephalus. Articles meeting specific criteria that had been delineated a priori were then examined, and data were abstracted and compiled in evidentiary tables. These data were then analyzed by the Pediatric Hydrocephalus Systematic Review and Evidence-Based Guidelines Task Force to consider evidence-based treatment recommendations. The search yielded 163 abstracts, which were screened for potential relevance to the application of technical adjuvants in shunt placement. Fourteen articles were selected for full-text review. One additional article was selected during a review of literature citations. Eight of these articles were included in the final recommendations concerning the use of endoscopy, ultrasonography, and electromagnetic image guidance during shunt placement, whereas the remaining articles were excluded due to poor evidence or lack of relevance. The evidence included 1 Class I, 1 Class II, and 6 Class III papers. An evidentiary table of relevant articles was created. CONCLUSIONS/RECOMMENDATION: There is insufficient evidence to recommend the use of endoscopic guidance for routine ventricular catheter placement. Level I, high degree of clinical certainty. The routine use of ultrasound-assisted catheter placement is an option. Level III, unclear clinical certainty. The routine use of computer-assisted electromagnetic (EM) navigation is an option. Level III, unclear clinical certainty.

Establishing Mandatory Academic Degree Guidance for AFROTC (Air Force Reserve Officer Training Corps) Rated Officer Accessions

DTIC Science & Technology

1984-04-01

Scientific- Architecture 4% 4% Technical Computer Sci 38% 37% Math 40% 40% Meteorology 6% 6% Physics 12 % 13% Nontechnical Quality Freeflow 2/ Quality...Architecture 4 Computer Sci 48 43 40 Math 30 35 38 Meteorology 6 6 6 Physics 12 12 12 Engineer Electrical 40% 50% 50% Aero Group 25 25 30 Other / 35 25 20...with Technical Degrees by Major Weapon System. . . 12 FIGURE 4 - Pilots with Technical Degrees by Category . . . . . . 13 FIGURE 5 - Regression

Substance Abuse and the Law: A Technical Assistance Paper for the Street Law Substance Abuse Lessons.

ERIC Educational Resources Information Center

National Inst. for Citizen Education in the Law, Washington, DC.

This technical assistance paper is designed to give trainers guidance on teaching the development and use of substance-abuse lessons found in "Street Law: A Course in Practical Law." The paper provides background on the lessons, a rationale for using the lessons, and sample agendas to use in training. "Street Law" contains…

78 FR 77673 - Notification of a Public Meeting of the Environmental Justice Technical Guidance Review Panel

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-24

... comment on May 9, 2013 (see https://www.federalregister.gov/articles/2013/05/09/2013-11165/technical..., 2013 (Volume 78 FR 107; 33416- 33417). The SAB Panel met on June 19-20, 2013 to learn about the... learn about the comments submitted by the public to the agency and to develop draft responses to the...

NASA Information Sciences and Human Factors Program

NASA Technical Reports Server (NTRS)

Holcomb, Lee; Hood, Ray; Montemerlo, Melvin; Jenkins, James; Smith, Paul; Dibattista, John; Depaula, Ramon; Hunter, Paul

1990-01-01

Fiscal year 1989 descriptions of technical accomplishments in seven sections are presented: automation and robotics; communications; computer sciences; controls and guidance; data systems; human factors; and sensor technology.

NASA information sciences and human factors program

NASA Technical Reports Server (NTRS)

Holcomb, Lee; Hood, Ray; Montemerlo, Melvin; Jenkins, James; Smith, Paul; Dibattista, John; Depaula, Ramon; Hunter, Paul; Lavery, David

1991-01-01

The FY-90 descriptions of technical accomplishments are contained in seven sections: Automation and Robotics, Communications, Computer Sciences, Controls and Guidance, Data Systems, Human Factors, and Sensor Technology.

fasab.gov

Science.gov Websites

fasab.gov Search Go About Board Activities Standards & Guidance Projects Resources Technical (7C13) Quick Links Handbook by Chapter Board Briefing Materials Subscribe to Mailing List fasab.gov

EPA Technical Support Centers (TSC): FY14 Lessons ...

EPA Pesticide Factsheets

EPA’s Technical Support Centers (TSC) included in ORD’s Safe and Healthy Communities (SHC) Research Action Plan fill the need for supplying subject-matter experts to continually assess state-of-the-art research and practices and channel this information to users in both direct applications (i.e., site-specific technical support) and general applications (i.e., technical transfer activities such as technical guidance documents, conferences, or workshops) . The TSCs are charged with providing solutions by: 1) linking EPA research to Agency decision-makers; 2) applying best practices to real world field applications; and 3) channeling feedback from field application to research communities. The TSP goal is to provide Regional Remedial Project Managers (RPMs), Corrective Action Staff, and On-Scene Coordinators (OSCs) with a diverse set of readily-accessible resources for technical assistance. This research summary provides six case studies – two from each of the three TSCs (Ground Water Technical Support Center, Engineering Technical Support Center, and Site Characterization Technical Support Center) – to exemplify and summarize the variety of TSC approaches that contribute to fulfilling the TSP mission. EPA’s Technical Support Centers (TSC) included in ORD’s Safe and Healthy Communities (SHC) Research Action Plan fill the need for supplying subject-matter experts to continually assess state-of-the-art research and practices and channel this informati

NASA Information Sciences and Human Factors Program

NASA Technical Reports Server (NTRS)

Holcomb, Lee (Editor); Hood, Ray (Editor); Montemerlo, Melvin (Editor); Sokoloski, Martin M. (Editor); Jenkins, James P. (Editor); Smith, Paul H. (Editor); Dibattista, John D. (Editor)

1988-01-01

The FY 1987 descriptions of technical accomplishments are contained for seven areas: automation and robotics, communications systems, computer sciences, controls and guidance, data systems, human factors, and sensor technology.

NASA information sciences and human factors program

NASA Technical Reports Server (NTRS)

Holcomb, Lee; Hood, Ray; Montemerlo, Melvin; Sokoloski, Martin; Jenkins, James; Smith, Paul; Dibattista, John

1989-01-01

The FY 1988 descriptions of technical accomplishments is presented in seven sections: Automation and Robotics, Communications Systems, Computer Sciences, Controls and Guidance, Data Systems, Human Factors, and Sensor Technology.

Septic Systems

EPA Pesticide Factsheets

The web site provides guidance and technical assistance for homeowners, government officials, industry professionals, and EPA partners about how to properly develop and manage individual onsite and community cluster systems that treat domestic wastewater.

15 CFR 950.2 - Environmental Data and Information Service (EDIS).

Code of Federal Regulations, 2010 CFR

2010-01-01

..., archives, analyzes, and disseminates worldwide environmental (atmospheric, marine, solar, and solid Earth... other economic systems; and manages or provides functional guidance for NOAA's scientific and technical...

15 CFR 950.2 - Environmental Data and Information Service (EDIS).

Code of Federal Regulations, 2011 CFR

2011-01-01

..., archives, analyzes, and disseminates worldwide environmental (atmospheric, marine, solar, and solid Earth... other economic systems; and manages or provides functional guidance for NOAA's scientific and technical...

24 CFR 26.47 - Evidence.

Code of Federal Regulations, 2010 CFR

2010-04-01

... this part, the Federal Rules of Evidence shall provide guidance to the ALJ's evidentiary ruling, but shall not be binding. Parties may object to clearly irrelevant material, but technical and hearsay...

Impaired Waters and TMDLs

EPA Pesticide Factsheets

The 303(d) program provides guidance and technical resources to assist States in submitting lists of impaired waterbodies and the development of Total Maximum Daily Loads of the pollutant causing the impairment.

Technical Note: Thoracic duct embolization for treatment of chylothorax: A novel guidance technique for puncture using combined MRI and fluoroscopy

PubMed Central

Praveen, Alampath; Sreekumar, Karumathil Pullara; Nazar, Puthukudiyil Kader; Moorthy, Srikanth

2012-01-01

Thoracic duct embolization (TDE) is an established radiological interventional procedure for thoracic duct injuries. Traditionally, it is done under fluoroscopic guidance after opacifying the thoracic duct with bipedal lymphangiography. We describe our experience in usinga heavily T2W sequence for guiding thoracic duct puncture and direct injection of glue through the puncture needle without cannulating the duct. PMID:23162248

Added Value of Contrast-Enhanced Ultrasound on Biopsies of Focal Hepatic Lesions Invisible on Fusion Imaging Guidance.

PubMed

Kang, Tae Wook; Lee, Min Woo; Song, Kyoung Doo; Kim, Mimi; Kim, Seung Soo; Kim, Seong Hyun; Ha, Sang Yun

2017-01-01

To assess whether contrast-enhanced ultrasonography (CEUS) with Sonazoid can improve the lesion conspicuity and feasibility of percutaneous biopsies for focal hepatic lesions invisible on fusion imaging of real-time ultrasonography (US) with computed tomography/magnetic resonance images, and evaluate its impact on clinical decision making. The Institutional Review Board approved this retrospective study. Between June 2013 and January 2015, 711 US-guided percutaneous biopsies were performed for focal hepatic lesions. Biopsies were performed using CEUS for guidance if lesions were invisible on fusion imaging. We retrospectively evaluated the number of target lesions initially invisible on fusion imaging that became visible after applying CEUS, using a 4-point scale. Technical success rates of biopsies were evaluated based on histopathological results. In addition, the occurrence of changes in clinical decision making was assessed. Among 711 patients, 16 patients (2.3%) were included in the study. The median size of target lesions was 1.1 cm (range, 0.5-1.9 cm) in pre-procedural imaging. After CEUS, 15 of 16 (93.8%) focal hepatic lesions were visualized. The conspicuity score was significantly increased after adding CEUS, as compared to that on fusion imaging (p < 0.001). The technical success rate of biopsy was 87.6% (14/16). After biopsy, there were changes in clinical decision making for 11 of 16 patients (68.8%). The addition of CEUS could improve the conspicuity of focal hepatic lesions invisible on fusion imaging. This dual guidance using CEUS and fusion imaging may affect patient management via changes in clinical decision-making.

Hydromodification and Habitat Alteration: National Management Measures

EPA Pesticide Factsheets

This guidance document provides technical assistance to states, territories, tribes, and the public for managing hydromodification activities and reducing associated NPS pollution of surface and ground water. The document describes

46 CFR 197.580 - Appendices.

Code of Federal Regulations, 2012 CFR

2012-10-01

... PROVISIONS Benzene § 197.580 Appendices. (a) Appendices A through D and F of this subpart contain technical information on benzene and its effects and provide guidance for medical surveillance, monitoring, and...

46 CFR 197.580 - Appendices.

Code of Federal Regulations, 2010 CFR

2010-10-01

... PROVISIONS Benzene § 197.580 Appendices. (a) Appendices A through D and F of this subpart contain technical information on benzene and its effects and provide guidance for medical surveillance, monitoring, and...

46 CFR 197.580 - Appendices.

Code of Federal Regulations, 2013 CFR

2013-10-01

... PROVISIONS Benzene § 197.580 Appendices. (a) Appendices A through D and F of this subpart contain technical information on benzene and its effects and provide guidance for medical surveillance, monitoring, and...

46 CFR 197.580 - Appendices.

Code of Federal Regulations, 2011 CFR

2011-10-01

... PROVISIONS Benzene § 197.580 Appendices. (a) Appendices A through D and F of this subpart contain technical information on benzene and its effects and provide guidance for medical surveillance, monitoring, and...

Characterizing complexity in socio-technical systems: a case study of a SAMU Medical Regulation Center.

PubMed

Righi, Angela Weber; Wachs, Priscila; Saurin, Tarcísio Abreu

2012-01-01

Complexity theory has been adopted by a number of studies as a benchmark to investigate the performance of socio-technical systems, especially those that are characterized by relevant cognitive work. However, there is little guidance on how to assess, systematically, the extent to which a system is complex. The main objective of this study is to carry out a systematic analysis of a SAMU (Mobile Emergency Medical Service) Medical Regulation Center in Brazil, based on the core characteristics of complex systems presented by previous studies. The assessment was based on direct observations and nine interviews: three of them with regulator of emergencies medical doctor, three with radio operators and three with telephone attendants. The results indicated that, to a great extent, the core characteristics of complexity are magnified) due to basic shortcomings in the design of the work system. Thus, some recommendations are put forward with a view to reducing unnecessary complexity that hinders the performance of the socio-technical system.

Actions Needed to Ensure Scientific and Technical Information is Adequately Reviewed at Goddard Space Flight Center, Johnson Space Center, Langley Research Center, and Marshall Space Flight Center

NASA Technical Reports Server (NTRS)

2008-01-01

This audit was initiated in response to a hotline complaint regarding the review, approval, and release of scientific and technical information (STI) at Johnson Space Center. The complainant alleged that Johnson personnel conducting export control reviews of STI were not fully qualified to conduct those reviews and that the reviews often did not occur until after the STI had been publicly released. NASA guidance requires that STI, defined as the results of basic and applied scientific, technical, and related engineering research and development, undergo certain reviews prior to being released outside of NASA or to audiences that include foreign nationals. The process includes technical, national security, export control, copyright, and trade secret (e.g., proprietary data) reviews. The review process was designed to preclude the inappropriate dissemination of sensitive information while ensuring that NASA complies with a requirement of the National Aeronautics and Space Act of 1958 (the Space Act)1 to provide for the widest practicable and appropriate dissemination of information resulting from NASA research activities. We focused our audit on evaluating the STI review process: specifically, determining whether the roles and responsibilities for the review, approval, and release of STI were adequately defined and documented in NASA and Center-level guidance and whether that guidance was effectively implemented at Goddard Space Flight Center, Johnson Space Center, Langley Research Center, and Marshall Space Flight Center. Johnson was included in the review because it was the source of the initial complaint, and Goddard, Langley, and Marshall were included because those Centers consistently produce significant amounts of STI.

Advanced Alarm Systems: Revision of Guidance and Its Technical Basis

DTIC Science & Technology

2000-11-01

was required to generalize from the unique aspects of individual experiments and studies to actual applications in the workplace . This is because...types of equipment used). For example , laboratory experiments often do not involve tasks of the complexity of NPP operations, and most experiments do...Cognitive Compatibility, Situation Awareness, Task Compatibility, and Timeliness. Figure 3.3 Example of an alarm system design review guideline Each

Technical Guidance Manual: Contaminant Flux Reduction Barriers for Managing Difficult-to-Treat Source Zones in Unconsolidated Media

DTIC Science & Technology

2017-06-20

was to evaluate if inexpensive flow reduction agents delivered via permeation grouting technology could help manage difficult-to-treat chlorinated...30  Table 4.  Description of Case Study Site ................................................................................... 30  Table 5...Intentionally Left Blank ES-1 EXECUTIVE SUMMARY Project Objective The overall objective of this project was to evaluate if inexpensive flow reduction

Guidance on the selection of cohorts for the extended one-generation reproduction toxicity study (OECD test guideline 443).

PubMed

Moore, Nigel P; Beekhuijzen, Manon; Boogaard, Peter J; Foreman, Jennifer E; North, Colin M; Palermo, Christine; Schneider, Steffen; Strauss, Volker; van Ravenzwaay, Bennard; Poole, Alan

2016-10-01

The extended one-generation reproduction toxicity study (EOGRTS; OECD test guideline 433) is a new and technically complex design to evaluate the putative effects of chemicals on fertility and development, including effects upon the developing nervous and immune systems. In addition to offering a more comprehensive assessment of developmental toxicity, the EOGRTS offers important improvements in animal welfare through reduction and refinement in a modular study design. The challenge to the practitioner is to know how the modular aspects of the study should be triggered on the basis of prior knowledge of a particular chemical, or on earlier findings in the EOGRTS itself, requirements of specific regulatory frameworks notwithstanding. The purpose of this document is to offer guidance on science-based triggers for these extended evaluations. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Research into the usage of integrated jamming of IR weakening and smoke-screen resisting the IR imaging guided missiles

NASA Astrophysics Data System (ADS)

Wang, Long-tao; Jiang, Ning; Lv, Ming-shan

2015-10-01

With the emergence of the anti-ship missle with the capability of infrared imaging guidance, the traditional single jamming measures, because of the jamming mechanism and technical flaws or unsuitable use, greatly reduced the survival probability of the war-ship in the future naval battle. Intergrated jamming of IR weakening + smoke-screen Can not only make jamming to the search and tracking of IR imaging guidance system , but also has feasibility in conjunction, besides , which also make the best jamming effect. The research conclusion has important realistic meaning for raising the antimissile ability of surface ships. With the development of guidance technology, infrared guidance system has expanded by ir point-source homing guidance to infrared imaging guidance, Infrared imaging guidance has made breakthrough progress, Infrared imaging guidance system can use two-dimensional infrared image information of the target, achieve the precise tracking. Which has Higher guidance precision, better concealment, stronger anti-interference ability and could Target the key parts. The traditional single infrared smoke screen jamming or infrared decoy flare interference cannot be imposed effective interference. So, Research how to effectively fight against infrared imaging guided weapons threat measures and means, improving the surface ship antimissile ability is an urgent need to solve.

The International Safety Framework for nuclear power source applications in outer space-Useful and substantial guidance

NASA Astrophysics Data System (ADS)

Summerer, L.; Wilcox, R. E.; Bechtel, R.; Harbison, S.

2015-06-01

In 2009, the International Safety Framework for Nuclear Power Source Applications in Outer Space was adopted, following a multi-year process that involved all major space faring nations under the auspices of a partnership between the UN Committee on the Peaceful Uses of Outer Space and the International Atomic Energy Agency. The Safety Framework reflects an international consensus on best practices to achieve safety. Following the 1992 UN Principles Relevant to the Use of Nuclear Power Sources in Outer Space, it is the second attempt by the international community to draft guidance promoting the safety of applications of nuclear power sources in space missions. NPS applications in space have unique safety considerations compared with terrestrial applications. Mission launch and outer space operational requirements impose size, mass and other space environment limitations not present for many terrestrial nuclear facilities. Potential accident conditions could expose nuclear power sources to extreme physical conditions. The Safety Framework is structured to provide guidance for both the programmatic and technical aspects of safety. In addition to sections containing specific guidance for governments and for management, it contains technical guidance pertinent to the design, development and all mission phases of space NPS applications. All sections of the Safety Framework contain elements directly relevant to engineers and space mission designers for missions involving space nuclear power sources. The challenge for organisations and engineers involved in the design and development processes of space nuclear power sources and applications is to implement the guidance provided in the Safety Framework by integrating it into the existing standard space mission infrastructure of design, development and operational requirements, practices and processes. This adds complexity to the standard space mission and launch approval processes. The Safety Framework is deliberately generic to remain relevantly independent of technological progress, of national organisational setups and of space mission types. Implementing its guidance therefore leaves room for interpretation and adaptation. Relying on reported practices, we analyse the guidance particularly relevant to engineers and space mission designers.

A Career Guidance Curriculum for Ninth Grade Students. Occupational Cluster Learning Activities. Health-Technical. Part 2 of 2. Ninth Grade Career Guidance Project. Project Duration: July 16, 1979, to June 30, 1980.

ERIC Educational Resources Information Center

Cape May County Vocational Schools, NJ.

This second of two parts presents learning activities for four occupational clusters of a ninth-grade cluster program. It contains theory and hands-on activities that explore the occupational requirements and working environment of these areas to help students make intelligent decisions of possible career choices based on levels of interest and…

Fully automated urban traffic system

NASA Technical Reports Server (NTRS)

Dobrotin, B. M.; Hansen, G. R.; Peng, T. K. C.; Rennels, D. A.

1977-01-01

The replacement of the driver with an automatic system which could perform the functions of guiding and routing a vehicle with a human's capability of responding to changing traffic demands was discussed. The problem was divided into four technological areas; guidance, routing, computing, and communications. It was determined that the latter three areas being developed independent of any need for fully automated urban traffic. A guidance system that would meet system requirements was not being developed but was technically feasible.

Technical Risk Assessment. The Status of Current DoD Efforts

DTIC Science & Technology

1986-04-01

naililgocrsf .rv iC’.ti-I ’N tpi). 33-51 andti 62-7, 1 Prinicipal Findings Risk Assessment Guidance [will hats lidft i1fied many technical risk appro ach...8217Ertjvhcs Firt licr. ino st1andlard d1efiitio ’ n oft eciunival ris.k extsts. wit tim twitl.. A t iorifti nv. many program offivi-t have develtoped t he...based ol (fhe technical risk assessnient for the system. Assessment has many % possible approar!:"s. 1 ’siiahly. one- or moh re tech- nical experts

A Review of Legal Decisions Relevant to Technical Standards Used in Pharmacy School Admissions

PubMed Central

2017-01-01

The implementation of an effective and legally sound technical standards procedure for pharmacy schools requires a proactive approach by admissions officers. Applicants with disabilities are accorded significant rights that must not be infringed during the admissions process in order to ensure compliance with applicable law. This article provides a review of applicable state cases, federal cases, and OCR decisions and guidance to help pharmacy schools identify procedures and implement technical standards into their admissions processes as required by ACPE Standards 2016. PMID:28381897

Control technology appendices for pollution control technical manuals. Final report, June 1982-February 1983

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1983-04-01

The document is one of six technical handbooks prepared by EPA to help government officials granting permits to build synfuels facilities, synfuels process developers, and other interested parties. They provide technical data on waste streams from synfuels facilities and technologies capable of controlling them. Process technologies covered in the manuals include coal gasification, coal liquefaction by direct and idirect processing, and the extraction of oil from shale. The manuals offer no regulatory guidance, allowing the industry flexibility in deciding how best to comply with environmental regulations.

Guidance and Control Software Project Data - Volume 4: Configuration Management and Quality Assurance Documents

NASA Technical Reports Server (NTRS)

Hayhurst, Kelly J. (Editor)

2008-01-01

The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes configuration management and quality assurance documents from the GCS project. Volume 4 contains six appendices: A. Software Accomplishment Summary for the Guidance and Control Software Project; B. Software Configuration Index for the Guidance and Control Software Project; C. Configuration Management Records for the Guidance and Control Software Project; D. Software Quality Assurance Records for the Guidance and Control Software Project; E. Problem Report for the Pluto Implementation of the Guidance and Control Software Project; and F. Support Documentation Change Reports for the Guidance and Control Software Project.

Voluntary Guidelines for Methamphetamine Laboratory Cleanup - Document

EPA Pesticide Factsheets

provides technical guidance for state and local personnel responsible for meth lab cleanup, based on an extensive review of the best available science and practices, and addresses general cleanup activities, specific items/materials, sampling.

RMP Guidance for Warehouses - Appendix C: Technical Assistance

EPA Pesticide Factsheets

Resources to assist warehousing facilities in complying include the Chemical Emergency Preparedness and Prevention Office website, EPCRA/Superfund/RCRA/CAA hotline, OSHA publications and training program, and Institute of Chemical Engineers publications.

RMP Guidance for Chemical Distributors - Appendix C: Technical Assistance

EPA Pesticide Factsheets

Resources available to assist warehousing facilities include the Office of Emergency Management website, EPCRA/Superfund/RCRA/CAA hotline, OSHA website and documents and training program, and American Institute of Chemical Engineers publications.

Urban Runoff: Model Ordinances for Aquatic Buffers

EPA Pesticide Factsheets

Aquatic Buffers serve as natural boundaries between local waterways and existing development. The model and example ordinaces below provide suggested language or technical guidance designed to create the most effective stream buffer zones possible.

Technical Solutions to Common Indoor Air Quality Issues in Schools

EPA Pesticide Factsheets

Indoor Air Quality (IAQ) Design Tools for Schools provides voluntary guidance for school personnel, architects, engineers, builders and contractors, parents, and the community on key school construction and renovation issues.

Feasibility of remote real-time guidance of a cardiac examination performed by novices using a pocket-sized ultrasound device.

PubMed

Mai, Tuan V; Ahn, David T; Phillips, Colin T; Agan, Donna L; Kimura, Bruce J

2013-01-01

Background. The potential of pocket-sized ultrasound devices (PUDs) to improve global healthcare delivery is limited by the lack of a suitable imaging protocol and trained users. Therefore, we investigated the feasibility of performing a brief, evidence-based cardiac limited ultrasound exam (CLUE) through wireless guidance of novice users. Methods. Three trainees applied PUDs on 27 subjects while directed by an off-site cardiologist to obtain a CLUE to screen for LV systolic dysfunction (LVSD), LA enlargement (LAE), ultrasound lung comets (ULC+), and elevated CVP (eCVP). Real-time remote audiovisual guidance and interpretation by the cardiologist were performed using the iPhone 4/iPod (FaceTime, Apple, Inc.) attached to the PUD and transmitted data wirelessly. Accuracy and technical quality of transmitted images were compared to on-site, gold-standard echo thresholds. Results. Novice versus sonographer imaging yielded technically adequate views in 122/135 (90%) versus 130/135 (96%) (P < 0.05). CLUE's combined SN, SP, and ACC were 0.67, 0.96, and 0.90. Technical adequacy (%) and accuracy for each abnormality (n) were LVSD (85%, 0.93, n = 5), LAE (89%, 0.74, n = 16), ULC+ (100%, 0.94, n = 5), and eCVP (78%, 0.91, n = 1). Conclusion. A novice can perform the CLUE using PUD when wirelessly guided by an expert. This method could facilitate PUD use for off-site bedside medical decision making and triaging of patients.

Quality assurance and quality control in mammography: a review of available guidance worldwide.

PubMed

Reis, Cláudia; Pascoal, Ana; Sakellaris, Taxiarchis; Koutalonis, Manthos

2013-10-01

Review available guidance for quality assurance (QA) in mammography and discuss its contribution to harmonise practices worldwide. Literature search was performed on different sources to identify guidance documents for QA in mammography available worldwide in international bodies, healthcare providers, professional/scientific associations. The guidance documents identified were reviewed and a selection was compared for type of guidance (clinical/technical), technology and proposed QA methodologies focusing on dose and image quality (IQ) performance assessment. Fourteen protocols (targeted at conventional and digital mammography) were reviewed. All included recommendations for testing acquisition, processing and display systems associated with mammographic equipment. All guidance reviewed highlighted the importance of dose assessment and testing the Automatic Exposure Control (AEC) system. Recommended tests for assessment of IQ showed variations in the proposed methodologies. Recommended testing focused on assessment of low-contrast detection, spatial resolution and noise. QC of image display is recommended following the American Association of Physicists in Medicine guidelines. The existing QA guidance for mammography is derived from key documents (American College of Radiology and European Union guidelines) and proposes similar tests despite the variations in detail and methodologies. Studies reported on QA data should provide detail on experimental technique to allow robust data comparison. Countries aiming to implement a mammography/QA program may select/prioritise the tests depending on available technology and resources. •An effective QA program should be practical to implement in a clinical setting. •QA should address the various stages of the imaging chain: acquisition, processing and display. •AEC system QC testing is simple to implement and provides information on equipment performance.

Lessons Learned in Over a Decade of Technical Support for U.S. Nuclear Cyber Security Programmes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Glantz, Clifford S.; Landine, Guy P.; Craig, Philip A.

Pacific Northwest National Laboratory’s (PNNL) nuclear cyber security team has been providing technical support to the U.S. Nuclear Regulatory Commission (NRC) since 2002. This team has provided cyber security technical experties in conducting cyber security inspections, developing of regulatory rules and guidance, reviewing facility cyber security plans, developing inspection guidance, and developing and teaching NRC inspectors how to conduct cyber security assessments. The extensive experience the PNNL team has gathered has allowed them to compile a lenghty list of recommendations on how to improve cyber security programs and conduct assessments. A selected set of recommendations are presented, including the needmore » to: integrate an array of defenisve strategies into a facility’s cyber security program, coordinate physical and cyber security activities, train phycial security forces to resist a cyber-enabled physical attack, improve estimates of the consequences of a cyber attack, properly resource cyber security assessments, appropropriately account for insider threats, routinely monitor security devices for potential attacks, supplement compliance-based requirements with risk-based decision making, and introduce the concept of resilience into cyber security programs.« less

Technical Support Document: 50% Energy Savings Design Technology Packages for Highway Lodging Buildings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jiang, Wei; Gowri, Krishnan; Lane, Michael D.

2009-09-28

This Technical Support Document (TSD) describes the process, methodology and assumptions for development of the 50% Energy Savings Design Technology Packages for Highway Lodging Buildings, a design guidance document intended to provide recommendations for achieving 50% energy savings in highway lodging properties over the energy-efficiency levels contained in ANSI/ASHRAE/IESNA Standard 90.1-2004, Energy Standard for Buildings Except Low-Rise Residential Buildings.

Intraarticular Sacroiliac Joint Injection Under Computed Tomography Fluoroscopic Guidance: A Technical Note to Reduce Procedural Time and Radiation Dose

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paik, Nam Chull, E-mail: pncspine@gmail.com

2016-07-15

PurposeA technique for computed tomography fluoroscopy (CTF)-guided intraarticular (IA) sacroiliac joint (SIJ) injection was devised to limit procedural time and radiation dose.MethodsOur Institutional Review Board approved this retrospective analysis and waived the requirement for informed consent. Overall, 36 consecutive diagnostic or therapeutic IA SIJ injections (unilateral, 20; bilateral, 16) performed in 34 patients (female, 18; male, 16) with a mean age of 45.5 years (range 20–76 years) under CTF guidance were analyzed, assessing technical success (i.e., IA contrast spread), procedural time, and radiation dose.ResultsAll injections were successful from a technical perspective and were free of serious complications. Respective median proceduralmore » times and effective doses of SIJ injection were as follows: unilateral, 5.28 min (range 3.58–8.00 min) and 0.11 millisievert (mSv; range 0.07–0.24 mSv); and bilateral, 6.72 min (range 4.17–21.17 min) and 0.11 mSv (range 0.09–0.51 mSv).ConclusionsGiven the high rate of technical success achieved in limited time duration and with little radiation exposure, CTF-guided IA SIJ injection is a practical and low-risk procedure.« less

Support increased adoption of green infrastructure into ...

EPA Pesticide Factsheets

This project will provide technical assistance to support implementation of GI in U.S. communities and information on best practices for GI approaches that protect ground water supplies. Case studies that can be more broadly applied to other communities will be conducted. The project will provide program and regional offices with guidance on GI planning, implementation, and maintenance for stormwater management and capture/aquifer storage. To share information on SSWR research projects

The Role and Function of the Vocational Education and Training in the New Economic Plan in Korea. Case Studies on Technical and Vocational Education in Asia and the Pacific.

ERIC Educational Resources Information Center

Kim, Taeck-Duck

Korea must develop a new policy framework to sustain its economic development. Democratic principles, such as voluntary participation and creative initiatives by the private sector, should replace government guidance and control as the economy's engine of growth. Major goals of the new economy are as follows: promotion of industrial structural…

CCA: Exploratory Case Study of Construction in a Contingency Environment

DTIC Science & Technology

2010-03-01

IN A CONTINGENCY ENVIRONMENT THESIS Presented to the Faculty Department of Systems and Engineering Management Graduate School of...process is not meeting the expectation of the war fighters. Furthermore, because it is not meeting the war fighter’s expectation the system is...Daniel Holt, Lt Col Jason Turner, Lt Col Robert Fass and G Richard Freeman (Technical Director of AF Center of Systems Engineering) for their guidance

Management of mediastinal syndromes in pediatrics: a new challenge of ultrasound guidance to avoid high-risk general anesthesia.

PubMed

Sola, Chrystelle; Choquet, Olivier; Prodhomme, Olivier; Capdevila, Xavier; Dadure, Christophe

2014-05-01

Adverse events associated with anesthetic management of anterior mediastinal masses in pediatrics are common. To avoid an extremely hazardous general anesthesia, the use of real-time ultrasonography offers an effective alternative in high-risk cases. We report the anesthetic management including a light sedation and ultrasound guidance for regional anesthesia, surgical node biopsy, and placement of a central venous line in two children with an anterior symptomatic mediastinal mass. For pediatric patients with clinical and/or radiologic signs of airway compression, ultrasound guidance provides safety technical assistance to avoid general anesthesia and should be performed for the initial diagnostic and therapeutic procedures. © 2013 John Wiley & Sons Ltd.

A Guidance Document for Kentucky's Oil and Gas Operations

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

1998-11-10

This technical report is a summary of the progress made for "A Guidance Document for Kentucky's Oil and Gas Operators". During this quarter, the document received continued review and editing in an elec-tronic format to satisfy the United States Department of Energy (DOE). Comments received from oil and gas operators reviewing this document prompted contact to be made with the United States Environmental Protection Agency (USEPA) to develop an addendum section to provide better explanation of USEPA requirements for Class II injection wells in Kentucky.

Underground Test Area Activity Preemptive Review Guidance Nevada National Security Site, Nevada, Revision 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farnham, Irene; Rehfeldt, Kenneth

Preemptive reviews (PERs) of Underground Test Area (UGTA) Activity corrective action unit (CAU) studies are an important and long-maintained quality improvement process. The CAU-specific PER committees provide internal technical review of ongoing work throughout the CAU lifecycle. The reviews, identified in the UGTA Quality Assurance Plan (QAP) (Sections 1.3.5.1 and 3.2), assure work is comprehensive, accurate, in keeping with the state of the art, and consistent with CAU goals. PER committees review various products, including data, documents, software/codes, analyses, and models. PER committees may also review technical briefings including Federal Facility Agreement and Consent Order (FFACO)-required presentations to the Nevadamore » Division of Environmental Protection (NDEP) and presentations supporting key technical decisions (e.g., investigation plans and approaches). PER committees provide technical recommendations to support regulatory decisions that are the responsibility of the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Field Office (NNSA/NFO) and NDEP.« less

Development of a Design Flexibility Toolkit : [Technical Summary

DOT National Transportation Integrated Search

2012-01-01

The American Association of State Highway and Transportation : Officials (AASHTO) publication titled A Policy : on Geometric Design of Highways and Streets (Green : Book) provides guidance to the designer by referencing : a recommended range of value...

7 CFR 653.2 - Technical standards and criteria.

Code of Federal Regulations, 2011 CFR

2011-01-01

... guidance and direction needed to assure that the practices meet the intended purpose and are of the quality needed to assure lasting for the design life. Standards and criteria are developed in consultation with...

7 CFR 653.2 - Technical standards and criteria.

Code of Federal Regulations, 2014 CFR

2014-01-01

... guidance and direction needed to assure that the practices meet the intended purpose and are of the quality needed to assure lasting for the design life. Standards and criteria are developed in consultation with...

7 CFR 653.2 - Technical standards and criteria.

Code of Federal Regulations, 2010 CFR

2010-01-01

... guidance and direction needed to assure that the practices meet the intended purpose and are of the quality needed to assure lasting for the design life. Standards and criteria are developed in consultation with...

7 CFR 653.2 - Technical standards and criteria.

Code of Federal Regulations, 2013 CFR

2013-01-01

... guidance and direction needed to assure that the practices meet the intended purpose and are of the quality needed to assure lasting for the design life. Standards and criteria are developed in consultation with...

7 CFR 653.2 - Technical standards and criteria.

Code of Federal Regulations, 2012 CFR

2012-01-01

... guidance and direction needed to assure that the practices meet the intended purpose and are of the quality needed to assure lasting for the design life. Standards and criteria are developed in consultation with...

20 CFR 641.130 - What is the scope of this part?

Code of Federal Regulations, 2010 CFR

2010-04-01

... GOVERNING THE SENIOR COMMUNITY SERVICE EMPLOYMENT PROGRAM Purpose and Definitions § 641.130 What is the... “additional guidance will be provided through administrative issuance” refer to the SCSEP Bulletins, technical...

Accessible Electronic and Information Technology: Standards, Procedures, and Guidance

EPA Pesticide Factsheets

Defines electronic and information technology (EIT), and the technical and functional performance criteria for EIT to comply with Section 508 accessibility standards. Includes EPA procedures for EIT approval, 508 complaints, and undue burden justification.

40 CFR 300.805 - Location of the administrative record file.

Code of Federal Regulations, 2011 CFR

2011-07-01

... availability of these guidance documents. (3) Publicly available technical literature not generated for the... literature is listed in the index to the administrative record file or the literature is cited in a document...

40 CFR 300.805 - Location of the administrative record file.

Code of Federal Regulations, 2012 CFR

2012-07-01

... availability of these guidance documents. (3) Publicly available technical literature not generated for the... literature is listed in the index to the administrative record file or the literature is cited in a document...

40 CFR 300.805 - Location of the administrative record file.

Code of Federal Regulations, 2014 CFR

2014-07-01

... availability of these guidance documents. (3) Publicly available technical literature not generated for the... literature is listed in the index to the administrative record file or the literature is cited in a document...

40 CFR 300.805 - Location of the administrative record file.

Code of Federal Regulations, 2013 CFR

2013-07-01

... availability of these guidance documents. (3) Publicly available technical literature not generated for the... literature is listed in the index to the administrative record file or the literature is cited in a document...

Report: Procedural Review of EPA’s Greenhouse Gases Endangerment Finding Data Quality Processes

EPA Pesticide Factsheets

Report #11-P-0702, September 26, 2011. EPA met statutory requirements for rulemaking and generally followed requirements and guidance related to ensuring the quality of the supporting technical information.

40 CFR 300.805 - Location of the administrative record file.

Code of Federal Regulations, 2010 CFR

2010-07-01

... availability of these guidance documents. (3) Publicly available technical literature not generated for the... literature is listed in the index to the administrative record file or the literature is cited in a document...

7 CFR 3800.3 - Functions.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., climate, and related crop monitoring activities. (d) Remote sensing. (1) Provide technical assistance, coordination, and guidance to Department agencies in planning, developing, and carrying out satellite remote... administrative, management, and budget information relating to Department's remote sensing activities. ...

Improve FREQ macroscopic freeway analysis model

DOT National Transportation Integrated Search

2008-07-01

The primary objectives of this project have been to provide technical assistance on district freeway analysis projects, enhance the FREQ model based on guidance and suggestions from Caltrans staff members, and offer three freeway analysis workshops f...

Concise Review: Guidance in Developing Commercializable Autologous/Patient-Specific Cell Therapy Manufacturing

PubMed Central

Armant, Myriam; Brandwein, Harvey; Burger, Scott; Campbell, Andrew; Carpenito, Carmine; Clarke, Dominic; Fong, Timothy; Karnieli, Ohad; Niss, Knut; Van't Hof, Wouter; Wagey, Ravenska

2013-01-01

Cell therapy is poised to play an enormous role in regenerative medicine. However, little guidance is being made available to academic and industrial entities in the start-up phase. In this technical review, members of the International Society for Cell Therapy provide guidance in developing commercializable autologous and patient-specific manufacturing strategies from the perspective of process development. Special emphasis is placed on providing guidance to small academic or biotech researchers as to what simple questions can be addressed or answered at the bench in order to make their cell therapy products more feasible for commercial-scale production. We discuss the processes that are required for scale-out at the manufacturing level, and how many questions can be addressed at the bench level. The goal of this review is to provide guidance in the form of topics that can be addressed early in the process of development to better the chances of the product being successful for future commercialization. PMID:24101671

DOE Waste Treatability Group Guidance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kirkpatrick, T.D.

1995-01-01

This guidance presents a method and definitions for aggregating U.S. Department of Energy (DOE) waste into streams and treatability groups based on characteristic parameters that influence waste management technology needs. Adaptable to all DOE waste types (i.e., radioactive waste, hazardous waste, mixed waste, sanitary waste), the guidance establishes categories and definitions that reflect variations within the radiological, matrix (e.g., bulk physical/chemical form), and regulated contaminant characteristics of DOE waste. Beginning at the waste container level, the guidance presents a logical approach to implementing the characteristic parameter categories as part of the basis for defining waste streams and as the solemore » basis for assigning streams to treatability groups. Implementation of this guidance at each DOE site will facilitate the development of technically defined, site-specific waste stream data sets to support waste management planning and reporting activities. Consistent implementation at all of the sites will enable aggregation of the site-specific waste stream data sets into comparable national data sets to support these activities at a DOE complex-wide level.« less

Making intelligent systems team players: Additional case studies

NASA Technical Reports Server (NTRS)

Malin, Jane T.; Schreckenghost, Debra L.; Rhoads, Ron W.

1993-01-01

Observations from a case study of intelligent systems are reported as part of a multi-year interdisciplinary effort to provide guidance and assistance for designers of intelligent systems and their user interfaces. A series of studies were conducted to investigate issues in designing intelligent fault management systems in aerospace applications for effective human-computer interaction. The results of the initial study are documented in two NASA technical memoranda: TM 104738 Making Intelligent Systems Team Players: Case Studies and Design Issues, Volumes 1 and 2; and TM 104751, Making Intelligent Systems Team Players: Overview for Designers. The objective of this additional study was to broaden the investigation of human-computer interaction design issues beyond the focus on monitoring and fault detection in the initial study. The results of this second study are documented which is intended as a supplement to the original design guidance documents. These results should be of interest to designers of intelligent systems for use in real-time operations, and to researchers in the areas of human-computer interaction and artificial intelligence.

Added Value of Contrast-Enhanced Ultrasound on Biopsies of Focal Hepatic Lesions Invisible on Fusion Imaging Guidance

PubMed Central

Kang, Tae Wook; Song, Kyoung Doo; Kim, Mimi; Kim, Seung Soo; Kim, Seong Hyun; Ha, Sang Yun

2017-01-01

Objective To assess whether contrast-enhanced ultrasonography (CEUS) with Sonazoid can improve the lesion conspicuity and feasibility of percutaneous biopsies for focal hepatic lesions invisible on fusion imaging of real-time ultrasonography (US) with computed tomography/magnetic resonance images, and evaluate its impact on clinical decision making. Materials and Methods The Institutional Review Board approved this retrospective study. Between June 2013 and January 2015, 711 US-guided percutaneous biopsies were performed for focal hepatic lesions. Biopsies were performed using CEUS for guidance if lesions were invisible on fusion imaging. We retrospectively evaluated the number of target lesions initially invisible on fusion imaging that became visible after applying CEUS, using a 4-point scale. Technical success rates of biopsies were evaluated based on histopathological results. In addition, the occurrence of changes in clinical decision making was assessed. Results Among 711 patients, 16 patients (2.3%) were included in the study. The median size of target lesions was 1.1 cm (range, 0.5–1.9 cm) in pre-procedural imaging. After CEUS, 15 of 16 (93.8%) focal hepatic lesions were visualized. The conspicuity score was significantly increased after adding CEUS, as compared to that on fusion imaging (p < 0.001). The technical success rate of biopsy was 87.6% (14/16). After biopsy, there were changes in clinical decision making for 11 of 16 patients (68.8%). Conclusion The addition of CEUS could improve the conspicuity of focal hepatic lesions invisible on fusion imaging. This dual guidance using CEUS and fusion imaging may affect patient management via changes in clinical decision-making. PMID:28096725

Creating the Future of Evidence-Based Nutrition Recommendations: Case Studies from Lipid Research123

PubMed Central

Dwyer, Johanna T; Rubin, Kristin H; Psota, Tricia L; Liska, DeAnn J; Montain, Scott J

2016-01-01

Strategic translational research is designed to address research gaps that answer specific guidance questions. It provides translational value with respect to nutrition guidance and regulatory and public policy. The relevance and the quality of evidence both matter in translational research. For example, design decisions regarding population, intervention, comparator, and outcome criteria affect whether or not high-quality studies are considered relevant to specific guidance questions and are therefore included as evidence within the context of systematic review frameworks used by authoritative food and health organizations. The process used in systematic reviews, developed by the USDA for its Nutrition Evidence Library, is described. An eating pattern and cardiovascular disease (CVD) evidence review is provided as an example, and factors that differentiated the studies considered relevant and included in that evidence base from those that were excluded are noted. Case studies on ω-3 (n–3) fatty acids (FAs) and industrial trans-FAs illustrate key factors vital to relevance and translational impact, including choice of a relevant population (e.g., healthy, at risk, or diseased subjects; general population or high-performance soldiers); dose and form of the intervention (e.g., food or supplement); use of relevant comparators (e.g., technically feasible and realistic); and measures for both exposure and outcomes (e.g., inflammatory markers or CVD endpoints). Specific recommendations are provided to help increase the impact of nutrition research on future dietary guidance, policy, and regulatory issues, particularly in the area of lipids. PMID:27422509

Implementation Guidance Document: Properties and Types of Significant Photothermal Retinal Lesion Injuries

DTIC Science & Technology

2017-04-17

if ii does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ORGANIZATION. 1. REPORT DATE (DD-MM-YYYY) 12...NUMBER Risk of Significant Injury Technical Working Group : Wesley Burgei, Shannon Foley, Matt Pandullo, Melissa Nass-Flores, George L. Fischer, Hugh...14. ABSTRACT The RSI Technical Working Group (TWG) developed a recommendation defining the properties and types of significant photothennal retinal

Guidelines for contingency planning NASA (National Aeronautics and Space Administration) ADP security risk reduction decision studies

NASA Technical Reports Server (NTRS)

Tompkins, F. G.

1984-01-01

Guidance is presented to NASA Computer Security Officials for determining the acceptability or unacceptability of ADP security risks based on the technical, operational and economic feasibility of potential safeguards. The risk management process is reviewed as a specialized application of the systems approach to problem solving and information systems analysis and design. Reporting the results of the risk reduction analysis to management is considered. Report formats for the risk reduction study are provided.

Real-Time 3D Fluoroscopy-Guided Large Core Needle Biopsy of Renal Masses: A Critical Early Evaluation According to the IDEAL Recommendations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kroeze, Stephanie G. C.; Huisman, Merel; Verkooijen, Helena M.

2012-06-15

Introduction: Three-dimensional (3D) real-time fluoroscopy cone beam CT is a promising new technique for image-guided biopsy of solid tumors. We evaluated the technical feasibility, diagnostic accuracy, and complications of this technique for guidance of large-core needle biopsy in patients with suspicious renal masses. Methods: Thirteen patients with 13 suspicious renal masses underwent large-core needle biopsy under 3D real-time fluoroscopy cone beam CT guidance. Imaging acquisition and subsequent 3D reconstruction was done by a mobile flat-panel detector (FD) C-arm system to plan the needle path. Large-core needle biopsies were taken by the interventional radiologist. Technical success, accuracy, and safety were evaluatedmore » according to the Innovation, Development, Exploration, Assessment, Long-term study (IDEAL) recommendations. Results: Median tumor size was 2.6 (range, 1.0-14.0) cm. In ten (77%) patients, the histological diagnosis corresponded to the imaging findings: five were malignancies, five benign lesions. Technical feasibility was 77% (10/13); in three patients biopsy results were inconclusive. The lesion size of these three patients was <2.5 cm. One patient developed a minor complication. Median follow-up was 16.0 (range, 6.4-19.8) months. Conclusions: 3D real-time fluoroscopy cone beam CT-guided biopsy of renal masses is feasible and safe. However, these first results suggest that diagnostic accuracy may be limited in patients with renal masses <2.5 cm.« less

Guidelines for deploying weather responsive operations in TxDOT traffic signals.

DOT National Transportation Integrated Search

2017-02-01

Inclement weather, such as rain, snow, fog, and ice, create special operational challenges for traffic : management agencies. This project provided Texas Department of Transportation with technical guidance : for improving safety and efficiency of si...

Collecting and Reporting P2 Results: Regional Measurement Guidance

EPA Pesticide Factsheets

Measuring results is an essential component of any successful P2 program and is one way to determine the success of a technical assistance or training effort. This PDF defines some terms of P2 measurement.

Marine safety manual, volume 4 : technical

DOT National Transportation Integrated Search

2005-01-01

A comprehensive manual which provides guidance on the application of Coast Guard regulations and explains the rationale behind their development is vital to the successful execution of the marine safety program. This volume is intended to serve that ...

Compliance Assurance Monitoring Technical Guidance Document Appendix A: Condenser Control Device

EPA Pesticide Factsheets

Compliance assurance monitoring is intended to provide a reasonable assurance of compliance with applicable requirements under the Clean Air Act for large emission units that rely on pollution control device equipment to achieve compliance.

77 FR 16271 - Biweekly Notice: Applications and Amendments to Facility Operating Licenses Involving No...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-20

... CFR 51.22(b), no environmental impact statement or environmental assessment need be prepared for these... guidance of Nuclear Energy Institute (NEI) 04-10, ``Risk-Informed Technical Specifications Initiative 5b...

General RMP Guidance - Appendix C: Technical Assistance

EPA Pesticide Factsheets

Contacts for resources available to facilities in complying with 40 CFR part 68 (risk management program) include Office of Emergency Prevention Preparedness and Response, EPCRA/Superfund/RCRA/CAA Call Center, and the Center for Chemical Process Safety.

Toxicity testing of polymer materials for dialysis equipment: reconsidering in vivo testing.

PubMed

Sauer, U G; Liebsch, M; Kolar, R

2000-01-01

In fulfilment of the aims of the European Union Biocidal Directive (Directive 98/8/EC), Technical Guidance Documents are currently being compiled. Part I of these Technical Guidance Documents covers data requirements for active substances and biocidal products. The Three Rs principle has been applied in certain parts of the toxicity and ecotoxicity testing scheme for pesticides, such as testing for acute oral toxicity, skin and eye irritation, skin sensitisation, and dermal absorption. Further recommendations on how to proceed with regard to the continuing replacement, reduction and refinement of animal experiments in this field of regulatory testing are included for consideration. In this context, besides stressing the necessity to validate and accept further alternatives, emphasis is placed on providing the possibility of waiving unnecessary tests and on the continuous evaluation of whether certain tests are needed at all. 2000 FRAME.

Malaria vaccine research and development: the role of the WHO MALVAC committee

PubMed Central

2013-01-01

The WHO Malaria Vaccine Advisory Committee (MALVAC) provides advice to WHO on strategic priorities, activities and technical issues related to global efforts to develop vaccines against malaria. MALVAC convened a series of meetings to obtain expert, impartial consensus views on the priorities and best practice for vaccine-related research and development strategies. The technical areas covered during these consultations included: guidance on clinical trial design for candidate sporozoite and asexual blood stage vaccines; measures of efficacy of malaria vaccines in Phase IIb and Phase III trials; standardization of immunoassays; the challenges of developing assays and designing trials for interventions against malaria transmission; modelling impact of anti-malarial interventions; whole organism malaria vaccines, and Plasmodium vivax vaccine-related research and evaluation. These informed discussions and opinions are summarized here to provide guidance on harmonization of strategies to help ensure high standards of practice and comparability between centres and the outcome of vaccine trials. PMID:24112689

Natural radioactivity in building materials in the European Union: a database and an estimate of radiological significance.

PubMed

Trevisi, R; Risica, S; D'Alessandro, M; Paradiso, D; Nuccetelli, C

2012-02-01

The authors set up a database of activity concentration measurements of natural radionuclides (²²⁶Ra, ²³²Th and ⁴⁰K) in building material. It contains about 10,000 samples of both bulk material (bricks, concrete, cement, natural- and phosphogypsum, sedimentary and igneous bulk stones) and superficial material (igneous and metamorphic stones) used in the construction industry in most European Union Member States. The database allowed the authors to calculate the activity concentration index I--suggested by a European technical guidance document and recently used as a basis for elaborating the draft Euratom Basic Safety Standards Directive--for bricks, concrete and phosphogypsum used in the European Union. Moreover, the percentage could be assessed of materials possibly subject to restrictions, if either of the two dose criteria proposed by the technical guidance were to be adopted. Copyright © 2011 Elsevier Ltd. All rights reserved.

Percutaneous foot joint needle placement using a C-arm flat-panel detector CT.

PubMed

Wiewiorski, Martin; Takes, Martin Thanh Long; Valderrabano, Victor; Jacob, Augustinus Ludwig

2012-03-01

Image guidance is valuable for diagnostic injections in foot orthopaedics. Flat-detector computed tomography (FD-CT) was implemented using a C-arm, and the system was tested for needle guidance in foot joint injections. FD-CT-guided joint infiltration was performed in 6 patients referred from the orthopaedic department for diagnostic foot injections. All interventions were performed utilising a flat-panel fluoroscopy system utilising specialised image guidance and planning software. Successful infiltration was defined by localisation of contrast media depot in the targeted joint. The pre- and post-interventional numeric analogue scale (NAS) pain score was assessed. All injections were technically successful. Contrast media deposit was documented in all targeted joints. Significant relief of symptoms was noted by all 6 participants. FD-CT-guided joint infiltration is a feasible method for diagnostic infiltration of midfoot and hindfoot joints. The FD-CT approach may become an alternative to commonly used 2D-fluoroscopically guidance.

Air/Superfund national technical guidance study series, Volume 2. Estimation of baseline air emission at Superfund sites. Interim report(Final)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1989-01-01

This volume is one in a series of manuals prepared for EPA to assist its Remedial Project Managers in the assessment of the air contaminant pathway and developing input data for risk assessment. The manual provides guidance on developing baseline-emission estimates from hazardous waste sites. Baseline-emission estimates (BEEs) are defined as emission rates estimated for a site in its undisturbed state. Specifically, the manual is intended to: Present a protocol for selecting the appropriate level of effort to characterize baseline air emissions; Assist site managers in designing an approach for BEEs; Describe useful technologies for developing site-specific baseline emission estimatesmore » (BEEs); Help site managers select the appropriate technologies for generating site-specific BEEs.« less

Techniques for Interventional MRI Guidance in Closed-Bore Systems.

PubMed

Busse, Harald; Kahn, Thomas; Moche, Michael

2018-02-01

Efficient image guidance is the basis for minimally invasive interventions. In comparison with X-ray, computed tomography (CT), or ultrasound imaging, magnetic resonance imaging (MRI) provides the best soft tissue contrast without ionizing radiation and is therefore predestined for procedural control. But MRI is also characterized by spatial constraints, electromagnetic interactions, long imaging times, and resulting workflow issues. Although many technical requirements have been met over the years-most notably magnetic resonance (MR) compatibility of tools, interventional pulse sequences, and powerful processing hardware and software-there is still a large variety of stand-alone devices and systems for specific procedures only.Stereotactic guidance with the table outside the magnet is common and relies on proper registration of the guiding grids or manipulators to the MR images. Instrument tracking, often by optical sensing, can be added to provide the physicians with proper eye-hand coordination during their navigated approach. Only in very short wide-bore systems, needles can be advanced at the extended arm under near real-time imaging. In standard magnets, control and workflow may be improved by remote operation using robotic or manual driving elements.This work highlights a number of devices and techniques for different interventional settings with a focus on percutaneous, interstitial procedures in different organ regions. The goal is to identify technical and procedural elements that might be relevant for interventional guidance in a broader context, independent of the clinical application given here. Key challenges remain the seamless integration into the interventional workflow, safe clinical translation, and proper cost effectiveness.

The Water Framework Directive: The Challenges of Testing and Validation of Guidance Documents

NASA Astrophysics Data System (ADS)

Barth, F.; Bidoglio, G.; Murray, C. N.; Zaldivar, J.; Bouraoui, F.

On the 23rd October 2000 the European Parliament and Council passed a Directive establishing a framework of community action in the field of water policy (Water Framework Directive- FWD). The Water Framework Directive (FWD) raises major challenges, these include an extremely demanding timetable, in particular in the nine preparatory years; the complexity of the text and the diversity of possible solutions to scientific, technical and practical questions. A further problem is that a common understanding and methodologies for the application of the different areas of the FWD do not necessarily exist. Member States have, historically, developed approaches to monitoring, impact assessment, economic analysis etc. that will need to be compared in order to be certain that they provide comparable level of results over the range of ecosystems covered in the European Union. Accession Countries will also have to start to adjust their environmental legislation to be compatible with EU Directives and standards. The Framework Water Directive imposes a series of deadlines for the reporting by Member States to the European Commission. In order to respond to this problem a Common Strategy on the Implementation of the Water Framework Directive is being developed by the European Commission and Member States. The aim of the development of this Common Strategy is to allow, as far as possible, a coherent and harmonious implementation of the Directive. Focus is on methodological questions related to a common understanding of the technical and scientific implications of the Directive. The aim is to clarify and develop, where appropriate, supporting technical and scientific information to assist in the practical implementation of the Directive. Guidance documents, advice for operational methods and other supporting documents will be developed for this purpose. A modular structure has been chosen for the overall strategy. The main modules are the key activities for the implementation process.. · Activity 1: Information sharing · Activity 2: Develop guidance on technical issues · Activity 3: Information and data management · Activity 4: Application, testing and validation The first three priorities have a more horizontal character. They are the key activities for developing a common understanding of the implementation of the Water Framework Directive. All these horizontal activities need to be integrated and made operational in the River Basin Management Plans. Activity 4 (Application, Testing and Validation) significantly contributes to this integration role by making these activities operational in the River Basin Management Plans. The integration step is crucial for the effective implementation of the WFD. The objective of Activity 4 is to ensure coherence amongst the different guidance documents and their cross applicability by testing the guidance documents in selected pilot river basins. To achieve these objectives a Network of pilot river basins and associated coastal zones (where applicable) will be identified, in close co- operation with WGs in Key Action 2, that are considered to represent a range of problems and conditions characteristic of those to be found in the application of the different guidelines. The Network of identified sites will used for testing and cross- validation of proposed WG guidelines. The Joint Research Centre is acting as the technical secretariat for the Scientific Coordination Committee who is responsible for Activity 4. The purpose of the present paper is to describe approach, methodology and timetable for integrated testing of guidance documents.

Closure of hazardous and mixed radioactive waste management units at DOE facilities. [Contains glossary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This is document addresses the Federal regulations governing the closure of hazardous and mixed waste units subject to Resource Conservation and Recovery Act (RCRA) requirements. It provides a brief overview of the RCRA permitting program and the extensive RCRA facility design and operating standards. It provides detailed guidance on the procedural requirements for closure and post-closure care of hazardous and mixed waste management units, including guidance on the preparation of closure and post-closure plans that must be submitted with facility permit applications. This document also provides guidance on technical activities that must be conducted both during and after closure ofmore » each of the following hazardous waste management units regulated under RCRA.« less

Reusing Cleaned Up Superfund Sites: Ecological Use Where Waste is Left on Site

EPA Pesticide Factsheets

The report draws from experiences at completedand current reuse projects, EPA technical guidance, and other sources to describe ecosystem characteristics and remediation approaches that have been used to accommodate ecological usesat Superfund sites wher

CRITICAL EVALUATION OF ECOLOGICAL INDICATORS

EPA Science Inventory

EPA's Office of Research and Development (ORD) has prepared fifteen technical guidelines to evaluate the suitability of an ecological indicator in a monitoring program. The guidelines were fashioned to provide a consistent framework for indicator review and to provide guidance fo...

TECHNICAL APPROACHES TO CHARACTERIZING AND CLEANUP OF AUTOMOTIVE RECYCLING BROWNFIELDS

EPA Science Inventory

The guidance document gives assistance to communities, decision-makers, states and municipalities, academia, and the private sector to address issues related to the redevelopment of Brownfields sites, specifically automotive recycling sites. The document helps users to understand...

Technical solutions to overcrowded park and ride facilities

DOT National Transportation Integrated Search

2007-05-01

This report presents the results on potential techniques to more efficiently utilize existing park and ride : technologies and plan for future changes to the park and ride facilities. It presents: : A summary of parking monitoring and parking guidanc...

Compliance Assurance Monitoring Technical Guidance Document Appendix A:Volatile Organic Compound (VOC) Controls

EPA Pesticide Factsheets

Compliance assurance monitoring is intended to provide a reasonable assurance of compliance with applicable requirements under the Clean Air Act for large emission units that rely on pollution control device equipment to achieve compliance.

Compliance Assurance Monitoring Technical Guidance Document Appendix A: Fabric Filter Control Devices

EPA Pesticide Factsheets

Compliance assurance monitoring is intended to provide a reasonable assurance of compliance with applicable requirements under the Clean Air Act for large emission units that rely on pollution control device equipment to achieve compliance.

Transportation management center data capture for performance and mobility measures guidebook.

DOT National Transportation Integrated Search

2013-03-01

The Guide to Transportation Management Center (TMC) Data Capture for Performance and Mobility Measures is a two-volume document consisting of this summary Guidebook and a Reference Manual. These documents provide technical guidance and recommended pr...

Compliance Assurance Monitoring Technical Guidance Document Appendix A: Wet Electrostatic Precipitator Control Device

EPA Pesticide Factsheets

Compliance assurance monitoring is intended to provide a reasonable assurance of compliance with applicable requirements under the Clean Air Act for large emission units that rely on pollution control device equipment to achieve compliance.

Compliance Assurance Monitoring Technical Guidance Document Appendix A: Electrostatic Precipitator Control Device

EPA Pesticide Factsheets

Compliance assurance monitoring is intended to provide a reasonable assurance of compliance with applicable requirements under the Clean Air Act for large emission units that rely on pollution control device equipment to achieve compliance.

Compliance Assurance Monitoring Technical Guidance Document Appendix A: Electrified Filter Bed Control Device

EPA Pesticide Factsheets

Compliance assurance monitoring is intended to provide a reasonable assurance of compliance with applicable requirements under the Clean Air Act for large emission units that rely on pollution control device equipment to achieve compliance.

Compliance Assurance Monitoring Technical Guidance Document Appendix A: Carbon Adsorber Control Device

EPA Pesticide Factsheets

Compliance assurance monitoring is intended to provide a reasonable assurance of compliance with applicable requirements under the Clean Air Act for large emission units that rely on pollution control device equipment to achieve compliance.

Compliance Assurance Monitoring Technical Guidance Document Appendix A: Particulate Matter (PM) Controls

EPA Pesticide Factsheets

Compliance assurance monitoring is intended to provide a reasonable assurance of compliance with applicable requirements under the Clean Air Act for large emission units that rely on pollution control device equipment to achieve compliance.

Compliance Assurance Monitoring Technical Guidance Document Appendix A: Control of Other Specific Compounds

EPA Pesticide Factsheets

Compliance assurance monitoring is intended to provide a reasonable assurance of compliance with applicable requirements under the Clean Air Act for large emission units that rely on pollution control device equipment to achieve compliance.

77 FR 320 - Agency Information Collection Activities: Notice of Request for Approval of a New Information...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-04

... targets. The research project includes a literature review of current guidance and practices, a technical... information; and (4) ways that the burden could be minimized, including the use of electronic technology...

Framework for Small-Scale Experiments in Software Engineering: Guidance and Control Software Project: Software Engineering Case Study

NASA Technical Reports Server (NTRS)

Hayhurst, Kelly J.

1998-01-01

Software is becoming increasingly significant in today's critical avionics systems. To achieve safe, reliable software, government regulatory agencies such as the Federal Aviation Administration (FAA) and the Department of Defense mandate the use of certain software development methods. However, little scientific evidence exists to show a correlation between software development methods and product quality. Given this lack of evidence, a series of experiments has been conducted to understand why and how software fails. The Guidance and Control Software (GCS) project is the latest in this series. The GCS project is a case study of the Requirements and Technical Concepts for Aviation RTCA/DO-178B guidelines, Software Considerations in Airborne Systems and Equipment Certification. All civil transport airframe and equipment vendors are expected to comply with these guidelines in building systems to be certified by the FAA for use in commercial aircraft. For the case study, two implementations of a guidance and control application were developed to comply with the DO-178B guidelines for Level A (critical) software. The development included the requirements, design, coding, verification, configuration management, and quality assurance processes. This paper discusses the details of the GCS project and presents the results of the case study.

Guidance and Control Software Project Data - Volume 1: Planning Documents

NASA Technical Reports Server (NTRS)

Hayhurst, Kelly J. (Editor)

2008-01-01

The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the planning documents from the GCS project. Volume 1 contains five appendices: A. Plan for Software Aspects of Certification for the Guidance and Control Software Project; B. Software Development Standards for the Guidance and Control Software Project; C. Software Verification Plan for the Guidance and Control Software Project; D. Software Configuration Management Plan for the Guidance and Control Software Project; and E. Software Quality Assurance Activities.

Guidance and Control Software Project Data - Volume 3: Verification Documents

NASA Technical Reports Server (NTRS)

Hayhurst, Kelly J. (Editor)

2008-01-01

The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the verification documents from the GCS project. Volume 3 contains four appendices: A. Software Verification Cases and Procedures for the Guidance and Control Software Project; B. Software Verification Results for the Pluto Implementation of the Guidance and Control Software; C. Review Records for the Pluto Implementation of the Guidance and Control Software; and D. Test Results Logs for the Pluto Implementation of the Guidance and Control Software.

Advanced approach for intraoperative MRI guidance and potential benefit for neurosurgical applications.

PubMed

Busse, Harald; Schmitgen, Arno; Trantakis, Christos; Schober, Ralf; Kahn, Thomas; Moche, Michael

2006-07-01

To present an advanced approach for intraoperative image guidance in an open 0.5 T MRI and to evaluate its effectiveness for neurosurgical interventions by comparison with a dynamic scan-guided localization technique. The built-in scan guidance mode relied on successive interactive MRI scans. The additional advanced mode provided real-time navigation based on reformatted high-quality, intraoperatively acquired MR reference data, allowed multimodal image fusion, and used the successive scans of the built-in mode for quick verification of the position only. Analysis involved tumor resections and biopsies in either scan guidance (N = 36) or advanced mode (N = 59) by the same three neurosurgeons. Technical, surgical, and workflow aspects were compared. The image quality and hand-eye coordination of the advanced approach were improved. While the average extent of resection, neurologic outcome after functional MRI (fMRI) integration, and diagnostic yield appeared to be slightly better under advanced guidance, particularly for the main surgeon, statistical analysis revealed no significant differences. Resection times were comparable, while biopsies took around 30 minutes longer. The presented approach is safe and provides more detailed images and higher navigation speed at the expense of actuality. The surgical outcome achieved with advanced guidance is (at least) as good as that obtained with dynamic scan guidance. (c) 2006 Wiley-Liss, Inc.

Technical note: real-time web-based wireless visual guidance system for radiotherapy.

PubMed

Lee, Danny; Kim, Siyong; Palta, Jatinder R; Kim, Taeho

2017-06-01

Describe a Web-based wireless visual guidance system that mitigates issues associated with hard-wired audio-visual aided patient interactive motion management systems that are cumbersome to use in routine clinical practice. Web-based wireless visual display duplicates an existing visual display of a respiratory-motion management system for visual guidance. The visual display of the existing system is sent to legacy Web clients over a private wireless network, thereby allowing a wireless setting for real-time visual guidance. In this study, active breathing coordinator (ABC) trace was used as an input for visual display, which captured and transmitted to Web clients. Virtual reality goggles require two (left and right eye view) images for visual display. We investigated the performance of Web-based wireless visual guidance by quantifying (1) the network latency of visual displays between an ABC computer display and Web clients of a laptop, an iPad mini 2 and an iPhone 6, and (2) the frame rate of visual display on the Web clients in frames per second (fps). The network latency of visual display between the ABC computer and Web clients was about 100 ms and the frame rate was 14.0 fps (laptop), 9.2 fps (iPad mini 2) and 11.2 fps (iPhone 6). In addition, visual display for virtual reality goggles was successfully shown on the iPhone 6 with 100 ms and 11.2 fps. A high network security was maintained by utilizing the private network configuration. This study demonstrated that a Web-based wireless visual guidance can be a promising technique for clinical motion management systems, which require real-time visual display of their outputs. Based on the results of this study, our approach has the potential to reduce clutter associated with wired-systems, reduce space requirements, and extend the use of medical devices from static usage to interactive and dynamic usage in a radiotherapy treatment vault.

Combustion: an oil spill mitigation tool

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1979-11-01

The technical feasibility of using combustion as an oil spill mitigation tool was studied. Part I of the two-part report is a practical guide oriented toward the needs of potential users, while Part II is the research or resource document from which the practical guidance was drawn. The study included theoretical evaluations of combustion of petroleum pool fires under the effects of weathering and an oil classification system related to combustion potential. The theoretical analysis of combustion is balanced by practical experience of oil burning and case history information. Decision elements are provided which can be used as a guidemore » for technical evaluations of a particular oil spill situation. The rationale for assessing technical feasibility is given in the context of other alternatives available for response to an oil spill. A series of research and technology development concepts are included for future research. The ethics of using oil burning are discussed as issues, concerns, and tradeoffs. A detailed annotated bibliography is appended along with a capsule review of a decade of oil burning studies and other support information.« less

78 FR 5810 - AHRQ Standing Workgroup for Quality Indicator Measure Specification

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-28

... AHRQ Quality Indicators (QIs), their technical specifications, and associated methodological issues.... The time- limited workgroup is more restricted to specific clinical or methodological issues, while..., data enhancements, and methodological advances. The standing workgroup may potentially provide guidance...

78 FR 22883 - AHRQ Standing Workgroup for Quality Indicator Measure Specification

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-17

... Quality Indicators (QIs), their technical specifications, and associated methodological issues. The...-limited workgroup is more restricted to specific clinical or methodological issues, while the standing... enhancements, and methodological advances. The standing workgroup may potentially provide guidance for the...

Compliance Assurance Monitoring Technical Guidance Document Appendix A: Scrubbers for Particulate Matter Control Devices

EPA Pesticide Factsheets

Compliance assurance monitoring is intended to provide a reasonable assurance of compliance with applicable requirements under the Clean Air Act for large emission units that rely on pollution control device equipment to achieve compliance.

TECHNICAL APPROACHES TO CHARACTERIZING AND CLEANING UP BROWNFIELDS SITES: RAILROAD YARDS

EPA Science Inventory

This guidance document gives assistance to communities, decision-makers, states and municipalities, academia, and the private sector to address issues related to the redevelopment of Brownfields sites, specifically railroad yards. The document helps users to understand the proble...

Improving the traffic safety culture in Kansas : technical summary.

DOT National Transportation Integrated Search

2017-01-01

The main objective of this research was to provide guidance to the Kansas Department of Transportation (KDOT) in establishing strategies to improve the traffic safety culture in Kansas. This was done by analyzing crash data with respect to the seven ...

Draft project management update to the Iowa DOT Project Development Manual : final report.

DOT National Transportation Integrated Search

2016-08-01

This work supported drafting project management guidance for the Iowa Department of Transportation (DOT). The goal is to : incorporate a greater focus on project management in their project development process. : A technical advisory committee (TAC) ...

76 FR 5494 - Pipeline Safety: Mechanical Fitting Failure Reporting Requirements

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-01

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Part... Safety: Mechanical Fitting Failure Reporting Requirements AGENCY: Pipeline and Hazardous Materials Safety... tightening. A widely accepted industry guidance document, Gas Pipeline Technical Committee (GPTC) Guide, does...

Design and maintainability considerations regarding the effects of suborbital flights on composite constructed vehicles

DOT National Transportation Integrated Search

2010-08-13

The Aerospace Corporation was tasked by the Volpe National Transportation Systems Center to provide technical support to the Federal Aviation Administration, Office of Commercial Space Transportation (FAA/AST), in developing guidance for AST and indu...

Transportation management center data capture for performance and mobility measures reference manual.

DOT National Transportation Integrated Search

2013-03-01

The Guide to Transportation Management Center (TMC) Data Capture for Performance and Mobility Measures is a two-volume document consisting of a summary Guidebook and this Reference Manual. These documents provide technical guidance and recommended pr...

PFAS methods and guidance for sampling and analyzing water and other environmental media (Technical Brief)

EPA Pesticide Factsheets

EPA's methods for analyzing PFAS in environmental media are in various stages of development. This fact sheet summarizes EPA's analytical methods development for groundwater, surface water, wastewater, and solids, including soils, sediments, and biosolids

WHOLE EFFLUENT TOXICITY: A REPORT FROM THE COLONIES

EPA Science Inventory

The purpose of this follow-up activity to the SETAC-sponsored Pellston Workshop on Whole Effluent Toxicity (WET) in 1996 is to "provide technical expert support on scientific guidance involving testing, characterization, and identifying sources of toxicity in complex effluents."

Compliance Assurance Monitoring Technical Guidance Document Appendix A: Scrubbers for Gaseous Pollutants Control Devices

EPA Pesticide Factsheets

Compliance assurance monitoring is intended to provide a reasonable assurance of compliance with applicable requirements under the Clean Air Act for large emission units that rely on pollution control device equipment to achieve compliance.

77 FR 64435 - Branch Technical Position on the Import of Non-U.S. Origin Radioactive Sources

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-22

... exclusion, initially adopted in a 1995 rule.\\3\\ In accordance with International Atomic Energy Agency (IAEA) Code of Conduct on the Safety and Security of Radioactive Sources and the IAEA supplemental Guidance on...

Multimodal system for the planning and guidance of bronchoscopy

NASA Astrophysics Data System (ADS)

Higgins, William E.; Cheirsilp, Ronnarit; Zang, Xiaonan; Byrnes, Patrick

2015-03-01

Many technical innovations in multimodal radiologic imaging and bronchoscopy have emerged recently in the effort against lung cancer. Modern X-ray computed-tomography (CT) scanners provide three-dimensional (3D) high-resolution chest images, positron emission tomography (PET) scanners give complementary molecular imaging data, and new integrated PET/CT scanners combine the strengths of both modalities. State-of-the-art bronchoscopes permit minimally invasive tissue sampling, with vivid endobronchial video enabling navigation deep into the airway-tree periphery, while complementary endobronchial ultrasound (EBUS) reveals local views of anatomical structures outside the airways. In addition, image-guided intervention (IGI) systems have proven their utility for CT-based planning and guidance of bronchoscopy. Unfortunately, no IGI system exists that integrates all sources effectively through the complete lung-cancer staging work flow. This paper presents a prototype of a computer-based multimodal IGI system that strives to fill this need. The system combines a wide range of automatic and semi-automatic image-processing tools for multimodal data fusion and procedure planning. It also provides a flexible graphical user interface for follow-on guidance of bronchoscopy/EBUS. Human-study results demonstrate the system's potential.

WHO Expert Committee on Specifications for Pharmaceutical Preparations. Forty-ninth report.

PubMed

2015-01-01

The Expert Committee on Specifications for Pharmaceutical Preparations works towards clear, independent and practical standards and guidelines for the quality assurance of medicines. Standards are developed by the Committee through worldwide consultation and an international consensus-building process. The following new guidelines were adopted and recommended for use. Revised procedure for the development of monographs and other texts for The International Pharmacopoeia; Revised updating mechanism for the section on radiopharmaceuticals in The International Pharmacopoeia; Revision of the supplementary guidelines on good manufacturing practices: validation, Appendix 7: non-sterile process validation; General guidance for inspectors on hold-time studies; 16 technical supplements to Model guidance for the storage and transport of time- and temperature-sensitive pharmaceutical products; Recommendations for quality requirements when plant-derived artemisinin is used as a starting material in the production of antimalarial active pharmaceutical ingredients; Multisource (generic) pharmaceutical products: guidelines on registration requirements to establish interchangeability: revision; Guidance on the selection of comparator pharmaceutical products for equivalence assessment of interchangeable multisource (generic) products: revision; and Good review practices: guidelines for national and regional regulatory authorities.

Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project. ACT/Control/Guidance System study. Volume 2: Appendices

NASA Technical Reports Server (NTRS)

1982-01-01

The integrated application of active controls (IAAC) technology to an advanced subsonic transport is reported. Supplementary technical data on the following topics are included: (1) 1990's avionics technology assessment; (2) function criticality assessment; (3) flight deck system for total control and functional features list; (4) criticality and reliability assessment of units; (5) crew procedural function task analysis; and (6) recommendations for simulation mechanization.

Regulatory aspects of oncology drug safety evaluation: past practice, current issues, and the challenge of new drugs.

PubMed

Rosenfeldt, Hans; Kropp, Timothy; Benson, Kimberly; Ricci, M Stacey; McGuinn, W David; Verbois, S Leigh

2010-03-01

The drug development of new anti-cancer agents is streamlined in response to the urgency of bringing effective drugs to market for patients with limited life expectancy. FDA's regulation of oncology drugs has evolved from the practices set forth in Arnold Lehman's seminal work published in the 1950s through the current drafting of a new International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) safety guidance for anti-cancer drug nonclinical evaluations. The ICH combines the efforts of the regulatory authorities of Europe, Japan, and the United States and the pharmaceutical industry from these three regions to streamline the scientific and technical aspects of drug development. The recent development of new oncology drug classes with novel mechanisms of action has improved survival rates for some cancers but also brings new challenges for safety evaluation. Here we present the legacy of Lehman and colleagues in the context of past and present oncology drug development practices and focus on some of the current issues at the center of an evolving harmonization process that will generate a new safety guidance for oncology drugs, ICH S9. The purpose of this new guidance will be to facilitate oncology drug development on a global scale by standardizing regional safety requirements.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shoaf, C.R.; Guth, D.J.

The Air Risk Information Support Center (Air RISC) was initiated in early 1988 by the US Environmental Protection Agency`s (EPA) Office of Health and Environmental Assessment (OHEA) and the Office of Air Quality Planning and Standards (OAQPS) as a technology transfer effort that would focus on providing information to state and local environmental agencies and to EPA Regional Offices in the areas of health, risk, and exposure assessment for toxic air pollutants. Technical information is fostered and disseminated by Air RISCs three primary activities: (1) a {open_quotes}hotline{close_quotes}, (2) quick turn-around technical assistance projects, and (3) general technical guidance projects. 1more » ref., 2 figs.« less

Blasting methods for heterogeneous rocks in hillside open-pit mines with high and steep slopes

NASA Astrophysics Data System (ADS)

Chen, Y. J.; Chang, Z. G.; Chao, X. H.; Zhao, J. F.

2017-06-01

In the arid desert areas in Xinjiang, most limestone quarries are hillside open-pit mines (OPMs) where the limestone is hard, heterogeneous, and fractured, and can be easily broken into large blocks by blasting. This study tried to find effective technical methods for blasting heterogeneous rocks in such quarries based on an investigation into existing problems encountered in actual mining at Hongshun Limestone Quarry in Xinjiang. This study provided blasting schemes for hillside OPMs with different heights and slopes. These schemes involve the use of vertical deep holes, oblique shallow holes, and downslope hole-by-hole sublevel or simultaneous detonation techniques. In each bench, the detonations of holes in a detonation unit occur at intervals of 25-50 milliseconds. The research findings can offer technical guidance on how to blast heterogeneous rocks in hillside limestone quarries.

Technical guidance for the development of a solid state image sensor for human low vision image warping

NASA Technical Reports Server (NTRS)

Vanderspiegel, Jan

1994-01-01

This report surveys different technologies and approaches to realize sensors for image warping. The goal is to study the feasibility, technical aspects, and limitations of making an electronic camera with special geometries which implements certain transformations for image warping. This work was inspired by the research done by Dr. Juday at NASA Johnson Space Center on image warping. The study has looked into different solid-state technologies to fabricate image sensors. It is found that among the available technologies, CMOS is preferred over CCD technology. CMOS provides more flexibility to design different functions into the sensor, is more widely available, and is a lower cost solution. By using an architecture with row and column decoders one has the added flexibility of addressing the pixels at random, or read out only part of the image.

Guidance and Control Software Project Data - Volume 2: Development Documents

NASA Technical Reports Server (NTRS)

Hayhurst, Kelly J. (Editor)

2008-01-01

The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the development documents from the GCS project. Volume 2 contains three appendices: A. Guidance and Control Software Development Specification; B. Design Description for the Pluto Implementation of the Guidance and Control Software; and C. Source Code for the Pluto Implementation of the Guidance and Control Software

Hubble Space Telescope: A cosmic time machine

NASA Technical Reports Server (NTRS)

Westphal, J. A.; Harms, R. J.; Brandt, J. C.; Bless, R. C.; Macchetto, F. D.; Jefferys, W. H.

1991-01-01

The mission of the Hubble Space Telescope (HST) is to explore the expanding and evolving universe. During the 3,000 operating hours every year for the next 15 years or more, the HST will be used to study: galaxies; pulsars; globular clusters; neighboring stars where planets may be forming; binary star systems; condensing gas clouds and their chemical composition; and the rings of Saturn and the swirling ultraviolet clouds of Venus. The major technical achievements - its nearly perfect mirrors, its precise guidance system of rate gyroscopes, reaction wheels, star trackers, and fine guidance sensors are briefly discussed. The scientific instruments on board HST are briefly described. The integration of the equipment and instruments is outlined. The Space Telescope Science Institute (STScI) has approved time for 162 observations from among 556 proposals. The mission operation and data flow are explained.

Technical tips to perform safe and effective ultrasound guided steroid joint injections in children.

PubMed

Parra, Dimitri A

2015-01-01

The aim of this article is to describe the technique used to perform ultrasound guided steroid joint injections in children in a group of joints that can be injected using ultrasound as the only image guidance modality. The technique is described and didactic figures are provided to illustrate key technical concepts. It is very important to be familiar with the sonographic appearance of the pediatric joints and the developing bone when performing ultrasound-guided joint injections in children.

Technical Evaluation Report on the Guidance and Control Panel Symposium (29th) on Air Traffic Management Civil/Military Systems and Technologies.

DTIC Science & Technology

1980-03-01

language, reliance upon instrumental (technical) versus biologi - cal ( human ) capabilities, etc. The latter - the appreciative one - is not expressed...infrastructure, and most of human contribution, should be ready for servi- cing the military scene in case of high tension, or in the context of hostility...already proven "feasible changes*. 10 81 In a similar way of improvement ( 751 and [ 771 give additional information about DABS and a DABS/ ATARS

Conceptual design study of a Harrier V/STOL research aircraft

NASA Technical Reports Server (NTRS)

Bode, W. E.; Berger, R. L.; Elmore, G. A.; Lacey, T. R.

1978-01-01

MCAIR recently completed a conceptual design study to define modification approaches to, and derive planning prices for the conversion of a two place Harrier to a V/STOL control, display and guidance research aircraft. Control concepts such as rate damping, attitude stabilization, velocity command, and cockpit controllers are to be demonstrated. Display formats will also be investigated, and landing, navigation and guidance systems flight tested. The rear cockpit is modified such that it can be quickly adapted to faithfully simulate the controls, displays and handling qualities of a Type A or Type B V/STOL. The safety pilot always has take command capability. The modifications studied fall into two categories: basic modifications and optional modifications. Technical descriptions of the basic modifications and of the optional modifications are presented. The modification plan and schedule as well as the test plan and schedule are presented. The failure mode and effects analysis, aircraft performance, aircraft weight, and aircraft support are discussed.

STRESSOR IDENTIFICATION: TECHNICAL GUIDANCE DOCUMENT

EPA Science Inventory

Since the inception of the Clean Water Act (CWA) in 1972, the rivers, lakes, estuaries, and wetlands of the United States have indeed become cleaner. The standard for meassuring these improvements are both chemical and biological. Yet, we know that many waterbodies still fail to ...

LAND DISPOSAL RESEARCH NEEDS - A FORWARD ORIENTED REVIEW

EPA Science Inventory

The U.S. Environmental Protection Agency (EPA) has been a leader in evaluating and developing land disposal methods that will protect human Health and the environment and in providing technical guidance to regulatory agency personnel, practicing engineers, and the public on th...

National Management Measures to Protect and Restore Wetlands and Riparian Areas for the Abatement of Nonpoint Source Pollution

EPA Pesticide Factsheets

Guidance includes technical assistance to state, local, and tribal program managers on means of reducing nonpoint source pollution of surface and ground water through the protection and restoration of wetlands and riparian areas.

COMMUNITY MULTISCALE AIR QUALITY MODELING SYSTEM (ONE ATMOSPHERE)

EPA Science Inventory

This task supports ORD's strategy by providing responsive technical support of EPA's mission and provides credible state of the art air quality models and guidance. This research effort is to develop and improve the Community Multiscale Air Quality (CMAQ) modeling system, a mu...

TECHNICAL APPROACHES TO CHARACTERIZING AND REDEVELOPING BROWNFIELDS SITES: MUNICIPAL LANDFILLS AND ILLEGAL DUMPS

EPA Science Inventory

The guidance document gives assistance to communities, decision-makers, states and municipalities, academia, and the private sector to address issues related to the redevelopment of Brownfields sites, specifically, municipal landfill and illegal dump sites. The document helps use...

EPA-SUPPORTED (ENVIRONMENTAL PROTECTION AGENCY-SUPPORTED) WASTELOAD ALLOCATION MODELS

EPA Science Inventory

Modeling is increasingly becoming part of the Wasteload Allocation Process. The U.S. EPA provides guidance, technical training and computer software in support of this program. This paper reviews the support available to modelers through the Wasteload Allocation Section of EPA's ...

Approaches to Partnerships: Who Shares Wins.

ERIC Educational Resources Information Center

Further Education Unit, London (England).

This bulletin identifies and discusses issues surrounding collaborative arrangements and partnerships for British technical colleges and gives guidance on identifying, setting up, and maintaining such arrangements. Some potential advantages and disadvantages of partnerships are listed. A checklist follows of the most common partners in…

32 CFR 264.3 - Background.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., Greece, Italy, Japan, The Netherlands, Norway, Portugal, Spain, Turkey, and the United Kingdom. The... the Technical Property Committees in Europe. The J-4, Hq. United States Forces Japan, Tokyo, Japan is... Defense Advisor, USRO; guidance transmitted for the United States representative in Japan shall be...

32 CFR 264.3 - Background.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., Greece, Italy, Japan, The Netherlands, Norway, Portugal, Spain, Turkey, and the United Kingdom. The... the Technical Property Committees in Europe. The J-4, Hq. United States Forces Japan, Tokyo, Japan is... Defense Advisor, USRO; guidance transmitted for the United States representative in Japan shall be...

32 CFR 264.3 - Background.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., Greece, Italy, Japan, The Netherlands, Norway, Portugal, Spain, Turkey, and the United Kingdom. The... the Technical Property Committees in Europe. The J-4, Hq. United States Forces Japan, Tokyo, Japan is... Defense Advisor, USRO; guidance transmitted for the United States representative in Japan shall be...

32 CFR 264.3 - Background.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., Greece, Italy, Japan, The Netherlands, Norway, Portugal, Spain, Turkey, and the United Kingdom. The... the Technical Property Committees in Europe. The J-4, Hq. United States Forces Japan, Tokyo, Japan is... Defense Advisor, USRO; guidance transmitted for the United States representative in Japan shall be...

Polymer Exemption Guidance Manual for premanufacture notices for new chemicals under the Toxic Substances Control Act (TSCA)

EPA Pesticide Factsheets

A technical manual to accompany, but not supersede the Premanufacture Notification Exemptions; Revisions of Exemptions for Polymers; Final Rule found at 40 CFR Part 723, (60) FR 16316-16336, published Wednesday, March 29, 1995.

ECOSYSTEM RESTORATION RESEARCH THROUGH THE NATIONAL RISK MANAGEMENT RESEARCH LABORATORY (NRMRL)

EPA Science Inventory

The Ecosystem Restoration Research Program underway through ORD's National Risk Management Research Laboratory (NRMRL) has the long-term goal of providing watershed managers with "..state-of-the-science field-evaluated tools, technical guidance, and decision-support systems for s...

RADON DIAGNOSTIC MEASUREMENT GUIDANCE FOR LARGE BUILDINGS - VOLUME 1. TECHNICAL REPORT

EPA Science Inventory

The report discusses the development of radon diagnostic procedures and mitigation strategies applicable to a variety of large non-residential buildings commonly found in Florida. The investigations document and evaluate the nature of radon occurrence and entry mechanisms for rad...

32 CFR 264.3 - Background.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., Greece, Italy, Japan, The Netherlands, Norway, Portugal, Spain, Turkey, and the United Kingdom. The... the Technical Property Committees in Europe. The J-4, Hq. United States Forces Japan, Tokyo, Japan is... Defense Advisor, USRO; guidance transmitted for the United States representative in Japan shall be...

Implementation of GPS Machine Controlled Grading - Phase III (2008) and Technical Training

DOT National Transportation Integrated Search

2009-02-01

Beginning in 2006, WisDOT and the Construction Material and Support Center (CMSC) at UW-Madison worked together to develop the specifications and the QA/QC procedures for GPS machine guidance on highway grading projects. These specifications and proc...

U.S. regulatory research program for implementation of burnup credit in transport casks

DOT National Transportation Integrated Search

2001-09-10

In 1999 the U.S. Nuclear Regulatory Commission (U.S. NRC) initiated a research program to : support the development of technical bases and guidance that would facilitate the implementation of : burnup credit into licensing activities for transport an...

Comparison of Intraoperative Portable CT Scanners in Skull Base and Endoscopic Sinus Surgery: Single Center Case Series

PubMed Central

Conley, David B.; Tan, Bruce; Bendok, Bernard R.; Batjer, H. Hunt; Chandra, Rakesh; Sidle, Douglas; Rahme, Rudy J.; Adel, Joseph G.; Fishman, Andrew J.

2011-01-01

Precise and safe management of complex skull base lesions can be enhanced by intraoperative computed tomography (CT) scanning. Surgery in these areas requires real-time feedback of anatomic landmarks. Several portable CT scanners are currently available. We present a comparison of our clinical experience with three portable scanners in skull base and craniofacial surgery. We present clinical case series and the participants were from the Northwestern Memorial Hospital. Three scanners are studied: one conventional multidetector CT (MDCT), two digital flat panel cone-beam CT (CBCT) devices. Technical considerations, ease of use, image characteristics, and integration with image guidance are presented for each device. All three scanners provide good quality images. Intraoperative scanning can be used to update the image guidance system in real time. The conventional MDCT is unique in its ability to resolve soft tissue. The flat panel CBCT scanners generally emit lower levels of radiation and have less metal artifact effect. In this series, intraoperative CT scanning was technically feasible and deemed useful in surgical decision-making in 75% of patients. Intraoperative portable CT scanning has significant utility in complex skull base surgery. This technology informs the surgeon of the precise extent of dissection and updates intraoperative stereotactic navigation. PMID:22470270

Percutaneous magnetic resonance imaging-guided bone tumor management and magnetic resonance imaging-guided bone therapy.

PubMed

Sequeiros, Roberto Blanco; Fritz, Jan; Ojala, Risto; Carrino, John A

2011-08-01

Magnetic resonance imaging (MRI) is promising tool for image-guided therapy. In musculoskeletal setting, image-guided therapy is used to direct diagnostic and therapeutic procedures and to steer patient management. Studies have demonstrated that MRI-guided interventions involving bone, soft tissue, joints, and intervertebral disks are safe and in selected indications can be the preferred action to manage clinical situation. Often, these procedures are technically similar to those performed in other modalities (computed tomography, fluoroscopy) for bone and soft tissue lesions. However, the procedural perception to the operator can be very different to other modalities because of the vastly increased data.Magnetic resonance imaging guidance is particularly advantageous should the lesion not be visible by other modalities, for selective lesion targeting, intra-articular locations, cyst aspiration, and locations adjacent to surgical hardware. Palliative tumor-related pain management such as ablation therapy forms a subset of procedures that are frequently performed under MRI. Another suitable entity for MRI guidance are the therapeutic percutaneous osseous or joint-related benign or reactive conditions such as osteoid osteoma, epiphyseal bone bridging, osteochondritis dissecans, bone cysts, localized bone necrosis, and posttraumatic lesions. In this article, we will describe in detail the technical aspects of performing MRI-guided therapeutic musculoskeletal procedures as well as the clinical indications.

Emergency endotracheal intubation under fluoroscopy guidance for patients with acute dyspnea or asphyxia.

PubMed

Jiao, Dechao; Xie, Na; Han, Xinwei; Wu, Gang

2016-11-01

To evaluate the feasibility and effectiveness of emergency endotracheal intubation (EEI) under fluoroscopy guidance for patients with acute dyspnea or asphyxia. From October 2011 to October 2014, of 1521 patients with acute dyspnea or asphyxia who required EEI in 6 departments, 43 patients who experienced intubation difficulty or failure were entered into this study. Data on technical success, procedure time, complications, and clinical outcome were collected. The pulse oxygen saturation and Hugh-Jones classification changes were analyzed. Fluoroscopy-guided EEI was technically successful in all patients. Acute dyspnea had resolved in all patients with clinical success rate 100% after the procedure. There were no serious complications during or after the procedure. The pulse oxygen saturation and Hugh-Jones classification showed significant increase after EEI (P < .05). Further treatments, including tracheal stents (n = 21), surgical resection (n = 16), palliative tracheotomy (n = 4), and bronchoscopic treatment (n = 2), were performed 1 to 72 hours after EEI. During a mean follow-up period of 13.2 months, 13 patients had died and 30 patients remained alive without dyspnea. Fluoroscopy-guided EEI is a safe and feasible procedure, and may serve as an alternative treatment option for patients when traditional EEI is unsuccessful. Copyright © 2016 Elsevier Inc. All rights reserved.

Planning guidance for the Chemical Stockpile Emergency Preparedness Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shumpert, B.L.; Watson, A.P.; Sorensen, J.H.

1995-02-01

This planning guide was developed under the direction of the U.S. Army and the Federal Emergency Management Agency (FEMA) which jointly coordinate and direct the development of the Chemical Stockpile Emergency Preparedness Program (CSEPP). It was produced to assist state, local, and Army installation planners in formulating and coordinating plans for chemical events that may occur at the chemical agent stockpile storage locations in the continental United States. This document provides broad planning guidance for use by both on-post and off-post agencies and organizations in the development of a coordinated plan for responding to chemical events. It contains checklists tomore » assist in assuring that all important aspects are included in the plans and procedures developed at each Chemical Stockpile Disposal Program (CSDP) location. The checklists are supplemented by planning guidelines in the appendices which provide more detailed guidance regarding some issues. The planning guidance contained in this document will help ensure that adequate coordination between on-post and off-post planners occurs during the planning process. This planning guide broadly describes an adequate emergency planning base that assures that critical planning decisions will be made consistently at every chemical agent stockpile location. This planning guide includes material drawn from other documents developed by the FEMA, the Army, and other federal agencies with emergency preparedness program responsibilities. Some of this material has been developed specifically to meet the unique requirements of the CSEPP. In addition to this guidance, other location-specific documents, technical studies, and support studies should be used as needed to assist in the planning at each of the chemical agent stockpile locations to address the specific hazards and conditions at each location.« less

The process of developing audiovisual patient information: challenges and opportunities.

PubMed

Hutchison, Catherine; McCreaddie, May

2007-11-01

The aim of this project was to produce audiovisual patient information, which was user friendly and fit for purpose. The purpose of the audiovisual patient information is to inform patients about randomized controlled trials, as a supplement to their trial-specific written information sheet. Audiovisual patient information is known to be an effective way of informing patients about treatment. User involvement is also recognized as being important in the development of service provision. The aim of this paper is (i) to describe and discuss the process of developing the audiovisual patient information and (ii) to highlight the challenges and opportunities, thereby identifying implications for practice. A future study will test the effectiveness of the audiovisual patient information in the cancer clinical trial setting. An advisory group was set up to oversee the project and provide guidance in relation to information content, level and delivery. An expert panel of two patients provided additional guidance and a dedicated operational team dealt with the logistics of the project including: ethics; finance; scriptwriting; filming; editing and intellectual property rights. Challenges included the limitations of filming in a busy clinical environment, restricted technical and financial resources, ethical needs and issues around copyright. There were, however, substantial opportunities that included utilizing creative skills, meaningfully involving patients, teamworking and mutual appreciation of clinical, multidisciplinary and technical expertise. Developing audiovisual patient information is an important area for nurses to be involved with. However, this must be performed within the context of the multiprofessional team. Teamworking, including patient involvement, is crucial as a wide variety of expertise is required. Many aspects of the process are transferable and will provide information and guidance for nurses, regardless of specialty, considering developing this format of patient information.

A New Technique for Femoral Venous Access in Infants Using Arterial Injection Venous Return Guidance

PubMed Central

Ebishima, Hironori; Kitano, Masataka; Kurosaki, Kenichi; Shiraishi, Isao

2017-01-01

Objectives: Although venography guidance is helpful for central venous catheter placement, it is sometimes difficult to place a peripheral intravenous cannula for enhancement. We designed a new technique for establishing femoral venous access using venography guidance in the return phase of peripheral arteriography. This new technique was named arterial injection venous return guidance. Here we assessed the efficacy and safety of arterial injection venous return guidance. Methods: We reviewed data of 29 infants less than 6 months old undergoing catheter intervention at our institute in 2014. Of the 29 patients, femoral venous cannulation was performed using arterial injection venous return guidance in 5 patients, venography in 20 patients, and the landmark method in 4 patients. The technical success rates and incidence of complications were compared. Results: The overall success rates were 100% in the arterial injection venous return-guided and venography-guided groups. The mean procedure duration and mean contrast material injection time were similar between the groups. The contrast effect on the femoral vein in the arterial injection venous return-guided group was lower than that in the venography-guided group, but adequate for surgery. The overall complication rate was 17%, and obstruction of previously placed intravenous catheters was the most common complication. Conclusions: Therefore, the arterial injection venous return guidance technique was as safe and efficient as venography for establishing venous access. PMID:29034015

Three-dimensional Image Fusion Guidance for Transjugular Intrahepatic Portosystemic Shunt Placement.

PubMed

Tacher, Vania; Petit, Arthur; Derbel, Haytham; Novelli, Luigi; Vitellius, Manuel; Ridouani, Fourat; Luciani, Alain; Rahmouni, Alain; Duvoux, Christophe; Salloum, Chady; Chiaradia, Mélanie; Kobeiter, Hicham

2017-11-01

To assess the safety, feasibility and effectiveness of image fusion guidance with pre-procedural portal phase computed tomography with intraprocedural fluoroscopy for transjugular intrahepatic portosystemic shunt (TIPS) placement. All consecutive cirrhotic patients presenting at our interventional unit for TIPS creation from January 2015 to January 2016 were prospectively enrolled. Procedures were performed under general anesthesia in an interventional suite equipped with flat panel detector, cone-beam computed tomography (CBCT) and image fusion technique. All TIPSs were placed under image fusion guidance. After hepatic vein catheterization, an unenhanced CBCT acquisition was performed and co-registered with the pre-procedural portal phase CT images. A virtual path between hepatic vein and portal branch was made using the virtual needle path trajectory software. Subsequently, the 3D virtual path was overlaid on 2D fluoroscopy for guidance during portal branch cannulation. Safety, feasibility, effectiveness and per-procedural data were evaluated. Sixteen patients (12 males; median age 56 years) were included. Procedures were technically feasible in 15 of the 16 patients (94%). One procedure was aborted due to hepatic vein catheterization failure related to severe liver distortion. No periprocedural complications occurred within 48 h of the procedure. The median dose-area product was 91 Gy cm 2 , fluoroscopy time 15 min, procedure time 40 min and contrast media consumption 65 mL. Clinical benefit of the TIPS placement was observed in nine patients (56%). This study suggests that 3D image fusion guidance for TIPS is feasible, safe and effective. By identifying virtual needle path, CBCT enables real-time multiplanar guidance and may facilitate TIPS placement.

TECHNICAL GUIDANCE DOCUMENT: INSPECTION TECHNIQUES FOR THE FABRICATION OF GEOMEMBRANE FIELD SEAMS

EPA Science Inventory

Subtitle C of the Resource Conservation and Recovery Act (RCRA) requires the U.S. Environmental Protection Agency (EPA) to establish a Federal hazardous waste management program. This program must ensure that hazardous wastes are handled safely from generation until final dispos...

TECHNICAL APPROACHES TO CHARACTERIZING AND CLEANING UP BROWNFIELDS SITES: PULP AND PAPER MILLS

EPA Science Inventory

This guidance document gives assistance to communities, decision-makers, states and municipalities, academia, and the private sector to address issues related to the redevelopment of Brownfields sites, specifically pulp and paper mills sites. The document helps users to understan...

Professional Development for Career Educators. ERIC Digest.

ERIC Educational Resources Information Center

Brown, Bettina Lankard

New approaches to career and technical education (CTE) create new roles for career educators, including providing career awareness, counseling, guidance, and self-education. Career educators must understand and reflect upon career development theories; teaching and learning strategies; school-to-work practices; school/business linkages; and…

40 CFR 1.33 - Office of Administration and Resources Management.

Code of Federal Regulations, 2011 CFR

2011-07-01

... provides national program policy and technical guidance for: The acquisition of all information technology... acquired by grantees and contractors using Agency funds; the operation of all Agency computers and... Management Interns, OHRM establishes policies; assesses and projects Agency executive needs and workforce...

Technical Guidance for Constructing a Human Well-Being Index (HWBI): A Puerto Rico Example

EPA Science Inventory

The U.S. Environmental Protection Agency (EPA) Office of Research and Development’s Sustainable and Healthy Communities Research Program (EPA 2015) developed the Human Well-being Index (HWBI) as an integrative measure of economic, social, and environmental contributions to ...

The effectiveness and safety of traffic and non-traffic related messages presented on changeable message signs : technical summary.

DOT National Transportation Integrated Search

2008-08-01

Changeable message signs are electronic devices used along roadways to provide drivers with guidance related to traffic conditions and other events. Displayed messages can suggest that drivers take alternate routes in response to congestion, accident...

14 CFR 77.3 - Standards.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Standards. 77.3 Section 77.3 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE OBJECTS... section 16 of the Federal Airport Act; (3) Developing technical standards and guidance in the design and...

RADON REDUCTION TECHNIQUES FOR DETACHED HOUSES, TECHNICAL GUIDANCE (SECOND EDITION)

EPA Science Inventory

This document is intended for use by State officials, radon mitigation contractors, building contractors, concerned homeowners, and other persons as an aid in the selection, design, and operation of radon reduction measurements for houses. It is the second edition of EPA's techn...

40 CFR 1.33 - Office of Administration and Resources Management.

Code of Federal Regulations, 2012 CFR

2012-07-01

... provides national program policy and technical guidance for: The acquisition of all information technology... acquired by grantees and contractors using Agency funds; the operation of all Agency computers and... Management Interns, OHRM establishes policies; assesses and projects Agency executive needs and workforce...

40 CFR 1.33 - Office of Administration and Resources Management.

Code of Federal Regulations, 2014 CFR

2014-07-01

... provides national program policy and technical guidance for: The acquisition of all information technology... acquired by grantees and contractors using Agency funds; the operation of all Agency computers and... Management Interns, OHRM establishes policies; assesses and projects Agency executive needs and workforce...

40 CFR 1.33 - Office of Administration and Resources Management.

Code of Federal Regulations, 2013 CFR

2013-07-01

... provides national program policy and technical guidance for: The acquisition of all information technology... acquired by grantees and contractors using Agency funds; the operation of all Agency computers and... Management Interns, OHRM establishes policies; assesses and projects Agency executive needs and workforce...

Designing Needs Statements in a Systematic Iterative Way

ERIC Educational Resources Information Center

Verstegen, D. M. L.; Barnard, Y. F.; Pilot, A.

2009-01-01

Designing specifications for technically advanced instructional products, such as e-learning, simulations or simulators requires different kinds of expertise. The SLIM method proposes to involve all stakeholders from the beginning in a series of workshops under the guidance of experienced instructional designers. These instructional designers…

77 FR 2924 - Notice of Public Meeting and Request for Comment on the Branch Technical Position on the Import...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-20

... exclusion, initially adopted in a 1995 rule.\\3\\ In accordance with International Atomic Energy Agency (IAEA) Code of Conduct on the Safety and Security of Radioactive Sources and the IAEA supplemental Guidance on...

Designing Flightdeck Procedures: Literature Resources

NASA Technical Reports Server (NTRS)

Feldman, Jolene; Barshi, Immanuel; Degani, Asaf; Loukopoulou, Loukia; Mauro, Robert

2017-01-01

This technical publication contains the titles, abstracts, summaries, descriptions, and/or annotations of available literature sources on procedure design and development, requirements, and guidance. It is designed to provide users with an easy access to available resources on the topic of procedure design, and with a sense of the contents of these sources. This repository of information is organized into the following publication sources: Research (e.g., journal articles, conference proceedings), Manufacturers' (e.g., operation manuals, newsletters), and Regulatory and/or Government (e.g., advisory circulars, reports). An additional section contains synopses of Accident/Incident Reports involving procedures. This work directly supports a comprehensive memorandum by Barshi, Mauro, Degani, & Loukopoulou (2016) that summarizes the results of a multi-year project, partially funded by the FAA, to develop technical reference materials that support guidance on the process of developing cockpit procedures (see "Designing Flightdeck Procedures" https://ntrs.nasa.gov/archive/nasa/casi.ntrs.nasa.gov/20160013263.pdf). An extensive treatment of this topic is presented in a forthcoming book by the same authors.

Technical Guidance for Constructing a Human Well-Being ...

EPA Pesticide Factsheets

The U.S. Environmental Protection Agency (EPA) Office of Research and Development’s Sustainable and Healthy Communities Research Program (EPA 2015) developed the Human Well-being Index (HWBI) as an integrative measure of economic, social, and environmental contributions to well-being. The HWBI is composed of indicators and metrics representing eight domains of well-being: connection to nature, cultural fulfillment, education, health, leisure time, living standards, safety and security, and social cohesion. The domains and indicators in the HWBI were selected to provide a well-being framework that is broadly applicable to many different populations and communities, and can be customized using community-specific metrics. A primary purpose of this report is to adapt the US Human Well-Being Index (HWBI) to quantify human well-being for Puerto Rico. Additionally, our adaptation of the HWBI for Puerto Rico provides an example of how the HWBI can be adapted to different communities and technical guidance on processing data and calculating index using R.

Design Guidance for Command, Control, Communications, and Intelligence (C3I) Facility Cooling Systems

DTIC Science & Technology

1989-05-01

Typical ranges are from 50 to 70 OF. If a chiller is dedicated to serving water-cooled electronic equipment, the chilled water temperature setpoint can...can be satisfied with 50 OF chilled water. The COP of the dedicated chiller is improved by raising the chilled water setpoint , and the total life-cycle...USACERL TECHNICAL REPORT E-89/10 May 1989 Studies in Optimizing HVAC Hardware for C31 Facilities US Army Corps of Engineers Construction Engineering

Technical assistance from state health departments for communities engaged in policy, systems, and environmental change: the ACHIEVE Program.

PubMed

Hefelfinger, Jenny; Patty, Alice; Ussery, Ann; Young, Walter

2013-10-24

This study assessed the value of technical assistance provided by state health department expert advisors and by the staff of the National Association of Chronic Disease Directors (NACDD) to community groups that participated in the Action Communities for Health, Innovation, and Environmental Change (ACHIEVE) Program, a CDC-funded health promotion program. We analyzed quantitative and qualitative data reported by community project coordinators to assess the nature and value of technical assistance provided by expert advisors and NACDD staff and the usefulness of ACHIEVE resources in the development and implementation of community action plans. A grounded theory approach was used to analyze and categorize phrases in text data provided by community coordinators. Open coding placed conceptual labels on text phrases. Frequency distributions of the quantitative data are described and discussed. The most valuable technical assistance and program support resources were those determined to be in the interpersonal domain (ie, interactions with state expert advisors, NACDD staff, and peer-to-peer support). The most valuable technical assistance events were action institutes, coaches' meetings, webinars, and technical assistance conference calls. This analysis suggests that ACHIEVE communities valued the management and training assistance provided by expert advisors and NACDD staff. State health department expert advisors provided technical guidance and support, including such skills or knowledge-based services as best-practice strategies, review and discussion of community assessment data, sustainability planning, and identification of possible funding opportunities. NACDD staff led development and implementation of technical assistance events.

How accessible was information about H1N1 flu? Literacy assessments of CDC guidance documents for different audiences.

PubMed

Lagassé, Lisa P; Rimal, Rajiv N; Smith, Katherine C; Storey, J Douglas; Rhoades, Elizabeth; Barnett, Daniel J; Omer, Saad B; Links, Jonathan

2011-01-01

We assessed the literacy level and readability of online communications about H1N1/09 influenza issued by the Centers for Disease Control and Prevention (CDC) during the first month of outbreak. Documents were classified as targeting one of six audiences ranging in technical expertise. Flesch-Kincaid (FK) measure assessed literacy level for each group of documents. ANOVA models tested for differences in FK scores across target audiences and over time. Readability was assessed for documents targeting non-technical audiences using the Suitability Assessment of Materials (SAM). Overall, there was a main-effect by audience, F(5, 82) = 29.72, P<.001, but FK scores did not vary over time, F(2, 82) = .34, P>.05. A time-by-audience interaction was significant, F(10, 82) = 2.11, P<.05. Documents targeting non-technical audiences were found to be text-heavy and densely-formatted. The vocabulary and writing style were found to adequately reflect audience needs. The reading level of CDC guidance documents about H1N1/09 influenza varied appropriately according to the intended audience; sub-optimal formatting and layout may have rendered some text difficult to comprehend.

DEVELOPMENT PLAN FOR THE CAUSAL ANALYSIS / DIAGNOSIS DECISION INFORMATION SYSTEM (CADDIS) 2001-2004

EPA Science Inventory

The Causal Analysis/Diagnosis Decision Information System (CADDIS) is a web-based system that provides technical support for states, tribes and other users of the Office of Water's Stressor Identification Guidance. The Stressor Identific...

17 CFR 200.11 - Headquarters Office-Regional Office relationships.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Headquarters Office-Regional... General Organization § 200.11 Headquarters Office—Regional Office relationships. (a)(1) Division and... responsibility to the Commission for the overall development, policy and technical guidance, and policy direction...

Space Shuttle Technical Conference, part 1

NASA Technical Reports Server (NTRS)

Chaffee, N. (Compiler)

1985-01-01

Articles providing a retrospective presentation and documentation of the key scientific and engineering achievements of the Space Shuttle Program are compiled. Topics areas include: (1) integrated avionics; (2) guidance, navigation, and control; (3) aerodynamics; (4) structures; (5) life support; environmental control; and crew station; and (6) ground operations.

[Discuss about Alarm Requirements of Standards for Tests of Patient Monitor].

PubMed

Feng, Ting

This paper introduces the alarm requirements of standards of patient monitor and expounds their significance for tests and guidance for patient monitor, then discusses whether technical alarm should not be closed and it latching alarm and non-latching alarm can not exist together.

76 FR 22091 - Biomass Research and Development Technical Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-20

... DEPARTMENT OF ENERGY Energy Efficiency and Renewable Energy Biomass Research and Development...: Notice of Open Meeting. SUMMARY: This notice announces an open meeting of the Biomass Research and...: Purpose of Committee: To provide advice and guidance that promotes research and development leading to the...

Standardization Documents

DTIC Science & Technology

2011-08-01

Specifications and Standards; Guide Specifications; CIDs; and NGSs . Learn. Perform. Succeed. STANDARDIZATION DOCUMENTS Federal Specifications Commercial...national or international standardization document developed by a private sector association, organization, or technical society that plans ...Maintain lessons learned • Examples: Guidance for application of a technology; Lists of options Learn. Perform. Succeed. DEFENSE HANDBOOK

DESIGN, CONSTRUCTION, AND MAINTENANCE OF COVER SYSTEMS FOR HAZARDOUS WASTE: AN ENGINEERING GUIDANCE DOCUMENT

EPA Science Inventory

Engineering for cover over solid hazardous waste addresses complex interactions among many technical, environmental, and economical factors. The document emphasizes the special characteristics of solid waste management as they bear on the cover system while at the same time stres...

Proposed positive protection guidance for Kansas : synthesis of work zone positive protection devices and state practice : [technical summary].

DOT National Transportation Integrated Search

2013-02-01

The United States experiences over 700 fatalities and over 37,000 injuries each year in : temporary construction and maintenance work zones. The Federal Highway Administration : (FHWA) has implemented Temporary Traffic Control Devices 23 CFR 630 Subp...

PLANNING A NATURE CENTER.

ERIC Educational Resources Information Center

ASHBAUGH, BYRON L.

THIS BULLETIN IS PRODUCED BY THE NATURE CENTERS DIVISION, NATIONAL AUDUBON SOCIETY TO PROVIDE PROFESSIONAL GUIDANCE AND TECHNICAL KNOW-HOW IN THE DEVELOPMENT OF COMMUNITY NATURE AND CONSERVATION CENTERS. THE TOPICS COVERED ARE--(1) PURPOSE AND VALUE OF A NATURE AND CONSERVATION CENTER, (2) INITIAL CONSIDERATIONS SUCH AS COMMUNITY READINESS, LAND…

Recouple: Natural Resource Strategies for Rural Economic Development.

ERIC Educational Resources Information Center

Thomas, Margaret G.

This source book provides guidance and technical assistance material on utilizing forest, agricultural, and scenic and wildlife resources for rural economic development. The document focuses on the uniqueness of existing rural resources for new enterprise opportunities. Natural resource-based economic development strategies are a means to…

RADON-RESISTANT CONSTRUCTION TECHNIQUES FOR NEW RESIDENTIAL CONSTRUCTION: TECHNICAL GUIDANCE

EPA Science Inventory

Radon, a naturally occurring radioactive gas, is found in varying amounts in nearly all houses. The U.S. Environmental Protection Agency (EPA) has developed and demonstrated methods that have been used to reduce radon levels in existing houses. Many of these methods could be appl...

Human factors considerations in the design and evaluation of moving map displays of ownership on the airport surface

DOT National Transportation Integrated Search

2004-09-01

The Federal Aviation Administration (FAA) has requested human factors guidance to support the new moving map Technical Standard Order (TSO)-C165, Electronic Map Display Equipment for Graphical Depiction of Aircraft Position. This document was develop...

Day Care Infection Control Protocol.

ERIC Educational Resources Information Center

Seattle-King County Dept. of Public Health, Seattle, WA.

This day care infection control manual was assembled to provide technical guidance for the prevention and control of communicable diseases to child day care facilities in Seattle and King County, Washington. For each disease, the manual provides background information, public health control recommendations, and letters that can be used to…

Manned Venus Flyby

NASA Technical Reports Server (NTRS)

Feldman, M. S.; Ferrara, L. A.; Havenstein, P. L.; Volonte, J. E.; Whipple, P. H.

1967-01-01

This study is one of several being conducted at Bellcomm and in Manned Space Flight whose purpose is to give guidance to the Apollo Applications Program's technical objectives by focusing on a longer range goal. The assumed mission in this case is a three-man flyby of Venus launched in November, 1973 on a single standard Saturn V. The selected flight configuration includes a Command and Service Module similar in some respects to Apollo, an Environmental Support Module which occupies the adapter area and a spent S-IVB stage which is utilized for habitable volume and structural support of a solar cell electrical power system. The total injected weight, 106,775 lbs., is within the capability of a single Saturn V of the early 1970's. The study is focused on the selection of subsystem technologies appropriate to long duration flight. The conclusions are reported in terms of the technical characteristics to be achieved as part of the Apollo Applications Program's long duration objectives.

Sentinel lymph node biopsy under fluorescent indocyanin green guidance: Initial experience.

PubMed

Aydoğan, Fatih; Arıkan, Akif Enes; Aytaç, Erman; Velidedeoğlu, Mehmet; Yılmaz, Mehmet Halit; Sager, Muhammet Sait; Çelik, Varol; Uras, Cihan

2016-01-01

Sentinel lymph node biopsy can be applied by using either blue dye or radionuclide method or both in breast cancer. Fluorescent imaging with indocyanine green is a new defined method. This study evaluates the applicability of sentinel lymph node biopsy via fluorescent indocyanine green. IC-VIEW (Pulsion Medical Systems AG, Munich, Germany) infrared visualization system was used for imaging. Two mL of indocyanine green was injected to visualize sentinel lymph nodes. After injection, subcutaneous lymphatics were traced and sentinel lymph nodes were found with simultaneous imaging. Sentinel lymph nodes were excised under fluorescent light guidance, and excised lymph nodes were examined histopathologically. Patients with sentinel lymph node metastases underwent axillary dissection. Four patients with sentinel lymph node biopsy due to breast cancer were included in the study. Sentinel lymph nodes were visualized with indocyanine green in all patients. The median number of excised sentinel lymph node was 2 (2-3). Two patients with lymph node metastasis underwent axillary dissection. No metastasis was detected in lymph nodes other than the sentinel nodes in patients with axillary dissection. There was no complication during and after the operation related to the method. According to our limited experience, sentinel lymph node biopsy under fluorescent indocyanine green guidance, which has an advantage of simultaneous visualization, is technically feasible.

Ultrasound-Guided Angioplasty of Dysfunctional Vascular Access for Haemodialysis. The Pros and Cons

DOE Office of Scientific and Technical Information (OSTI.GOV)

García-Medina, J., E-mail: josegmedina57@gmail.com; García-Alfonso, J. J., E-mail: juanjozarandieta@gmail.com

PurposeTo describe the benefits and the disadvantages of angioplasty in dialysis fistulas using only ultrasound guidance.Materials and MethodsThis is a prospective study in 132 failing or non-maturing arteriovenous accesses that underwent 189 ultrasound-guided balloon angioplasties. The technical success was defined as non-use of X-ray fluoroscopy during the procedure.Results127 procedures (67%) were successfully completed without fluoroscopy. Most failures were due to difficulty to traverse aneurismal segments, as well as anastomotic stenoses. Including initial failures, the primary patency rates at 6, 12 months and 2 years were 75 ± 3, 41 ± 3 and 14 ± 2%, respectively.ConclusionEndovascular repair of the dysfunctional vascular access for haemodialysis under ultrasound guidance ismore » feasible and safe in roughly two-thirds of cases.« less

Going DEEP: guidelines for building simulation-based team assessments.

PubMed

Grand, James A; Pearce, Marina; Rench, Tara A; Chao, Georgia T; Fernandez, Rosemarie; Kozlowski, Steve W J

2013-05-01

Whether for team training, research or evaluation, making effective use of simulation-based technologies requires robust, reliable and accurate assessment tools. Extant literature on simulation-based assessment practices has primarily focused on scenario and instructional design; however, relatively little direct guidance has been provided regarding the challenging decisions and fundamental principles related to assessment development and implementation. The objective of this manuscript is to introduce a generalisable assessment framework supplemented by specific guidance on how to construct and ensure valid and reliable simulation-based team assessment tools. The recommendations reflect best practices in assessment and are designed to empower healthcare educators, professionals and researchers with the knowledge to design and employ valid and reliable simulation-based team assessments. Information and actionable recommendations associated with creating assessments of team processes (non-technical 'teamwork' activities) and performance (demonstration of technical proficiency) are presented which provide direct guidance on how to Distinguish the underlying competencies one aims to assess, Elaborate the measures used to capture team member behaviours during simulation activities, Establish the content validity of these measures and Proceduralise the measurement tools in a way that is systematically aligned with the goals of the simulation activity while maintaining methodological rigour (DEEP). The DEEP framework targets fundamental principles and critical activities that are important for effective assessment, and should benefit healthcare educators, professionals and researchers seeking to design or enhance any simulation-based assessment effort.

A model summer program for handicapped college students

NASA Technical Reports Server (NTRS)

Nissen, Anne B.

1989-01-01

During the summer of 1988, the Goddard Space Flight Center was the site of a new NASA project called A Model Summer Program for Handicapped College Students that was directed by Gallaudet University. The project's aim was to identify eight severely physically disabled college students (four from Gallaudet University and four from local historically black colleges and universities (HBCU's)) majoring in technical fields and to assign them technical projects related to aerospace which they would complete under the guidance of mentors who were full time employees of Goddard. A description of the program is presented.

76 FR 55067 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-06

... Pharmaceutical Current Good Manufacturing Practice AGENCY: Food and Drug Administration, HHS. ACTION: Notice... Good Manufacturing Practice--(OMB Control Number 0910-0563)--Extension The guidance is intended to... products, on how to resolve disputes of scientific and technical issues relating to current good...

Strategic Plan for Information Systems and Technology, Fiscal Years 1994-1998.

ERIC Educational Resources Information Center

National Archives and Records Administration, Washington, DC.

The information systems and technology management program of the National Archives and Records Administration (NARA) establishes broad policy guidance and technical standards for information management to ensure that appropriate resource sharing can occur, while providing cost-effective support for mission requirements of program offices. The NARA…

77 FR 72752 - Opioid Drugs in Maintenance and Detoxification Treatment of Opiate Addiction; Proposed...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-06

... buprenorphine products (Subutex[supreg] and Suboxone[supreg]) on October 8, 2002, and the DEA's rescheduling of....'' The same commenter suggested allowing Nurse Practitioners to become qualified to treat these patients... guidance for nurses in OTPs or other practice settings such as ``Technical Assistance Publication 30...

75 FR 15597 - Ensuring Enforcement and Implementation of Abortion Restrictions in the Patient Protection and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-29

... generally accepted accounting principles, OMB funds management circulars, and accounting guidance provided... exchanges that will be operational in 2014. The Act also imposes strict payment and accounting requirements... Federal financial assistance. The guidelines shall also offer technical information that States should...

Guidelines for replacement of deficient bridges with low-water stream crossings in the rural Midwest : technical summary.

DOT National Transportation Integrated Search

2017-02-01

This report provides guidance to public officials and engineers considering the replacement of a deficient or obsolete bridge with a low-water stream crossing (LWSC). An LWSC is a structure that is occasionally overtopped by floodwaters and is likely...

"Ohio 4-H CARTEENS": Peer Intervention Safety Program.

ERIC Educational Resources Information Center

Cropper, Rebecca J.

1999-01-01

Ohio 4-H's CARTEENS seeks to reduce juvenile traffic violations in a program designed and presented by teen peer educators with guidance and technical assistance from the state highway patrol. Teens examined court data to determine content, which includes defensive driving, rural road safety, and dealing with peer pressure. (SK)

Science to Support Informed Decision-Making: Examples from the US Environmental Protection Agency

EPA Science Inventory

The mission of the United States Environmental Protection Agency (US EPA) is to protect human health and the environment. We work to achieve our mission through a combination of applied research and technical guidance for localities, states, tribes, and regions to best manage the...

Teacher Cooperative Exchange Program: Evaluation Report. Summer Program, July-August, 1970.

ERIC Educational Resources Information Center

Cesta, Carmen A.

OBJECTIVES: To give teachers experience in business firms to help them improve teaching of vocational courses. DURATION: July-August 1970. AUDIENCE: Nine teacher participants are listed in the areas of business education, industrial arts, distributive education, industrial and technical education, occupational education, and guidance counseling.…

Radiation Heat Transfer

NASA Technical Reports Server (NTRS)

Sparrow, E. M.

1961-01-01

The pm-pose of this report is to describe work which has been carried out under the subject grant during the period from April 1, 1961, to October 1, 1961. Technical supervision and guidance of the work was provided by Mr. Seymour Lieblein, Chief, Flow Physics Branch, NASA Lewis Research Center, Cleveland, Ohio.

UAS Integration in the NAS Project: Part Task 6 V & V Simulation: Primary Results

NASA Technical Reports Server (NTRS)

Rorie, Conrad; Fern, Lisa; Shively, Jay; Santiago, Confesor

2016-01-01

This is a presentation of the preliminary results on final V and V (Verification and Validation) activity of [RTCA (Radio Technical Commission for Aeronautics)] SC (Special Committee)-228 DAA (Detect and Avoid) HMI (Human-Machine Interface) requirements for display alerting and guidance.

Specification of Training Simulator Fidelity: A Research Plan. Technical Report 558.

ERIC Educational Resources Information Center

Baum, David R.; And Others

This report presents a research plan to guide the determination of the empirical relationship between level of maintenance training simulator fidelity and training effectiveness. Chapter I describes data collection and analysis activities undertaken to provide guidance for fidelity decision making by the training simulator development community.…

Educational Reform and the World of Work: France. Reforms at the First Level of Secondary School

ERIC Educational Resources Information Center

Western European Education, 1977

1977-01-01

Investigates the effect of technical progress on educational reform in France. Factors considered include the lengthening of compulsory schooling, introduction of guidance and counseling facilities, vocational education reforms, and introduction of technology as a subject in the secondary school curriculum. (Author/DB)

Healthy People 2010: Oral Health Toolkit

ERIC Educational Resources Information Center

Isman, Beverly

2007-01-01

The purpose of this Toolkit is to provide guidance, technical tools, and resources to help states, territories, tribes and communities develop and implement successful oral health components of Healthy People 2010 plans as well as other oral health plans. These plans are useful for: (1) promoting, implementing and tracking oral health objectives;…

Evaluation of interactive highway safety design model crash prediction tools for two-lane rural roads on Kansas Department of Transportation projects : [technical summary].

DOT National Transportation Integrated Search

2014-01-01

Historically, project-level decisions for the selection of highway features to promote safety were based on either engineering judgment or adherence to accepted national guidance. These tools have allowed highway designers to produce facilities that ...

Flight Technical Error for Category B Non-Precision Approaches and Missed Approaches Using Non-Differential GPS for Course Guidance

DOT National Transportation Integrated Search

1993-11-01

Twelve general aviation pilots flew a Beechcraft Baron on 93 non-precision instrument approaches using a nondifferential : GPS receiver nodifled to satisfy selected functional requirements specified in TS0-C129. : The purposes of the effort were to d...

Seven Rules for Social Research

ERIC Educational Resources Information Center

Firebaugh, Glenn

2008-01-01

"Seven Rules for Social Research" teaches social scientists how to get the most out of their technical skills and tools, providing a resource that fully describes the strategies and concepts no researcher or student of human behavior can do without. Glenn Firebaugh provides indispensable practical guidance for anyone doing research in the social…

Careers in Science and Technical Communication

ERIC Educational Resources Information Center

Kastens, Kim

2007-01-01

This article provides practical guidance for science teachers to help students who love both science and writing, and are struggling to find a career that will allow them to combine these disparate talents and interests. It includes descriptions of career paths, suggestions for exploratory steps, and links to sources of additional information. The…

Exploring in Aeronautics. An Introduction to Aeronautical Sciences.

ERIC Educational Resources Information Center

National Aeronautics and Space Administration, Cleveland, OH. Lewis Research Center.

This curriculum guide is based on a year of lectures and projects of a contemporary special-interest Explorer program intended to provide career guidance and motivation for promising students interested in aerospace engineering and scientific professions. The adult-oriented program avoids technicality and rigorous mathematics and stresses real…

76 FR 33307 - Strengthen and Promote the Role of Local Health Departments in Retail Food Safety Regulation (U-50)

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-08

..., scientifically-based guidance, training, program evaluation, and technical assistance. B. Research/Cooperative... officials. NACCHO values guide staff and leadership in work to achieve optimal health for all through an... annual appropriations and successful performance. III. Paper Application, Registration, and Submission...

40 CFR 63.1367 - Recordkeeping requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... operator must keep records of the DOT certification required by § 63.1362(c)(6)(ii) and the pressure relief... permit authority, greater risk to human health or the environment than if the emission points were... guidance that the Administrator makes available for use or any other technically sound information or...

40 CFR 63.1259 - Recordkeeping requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... required by § 63.1253(f)(2) and the pressure relief vent setting and the leak detection records specified... human health or the environment than if the storage tanks and process vents were controlled according to... guidance that the Administrator makes available for use or any other technically sound information or...

Using Minimum Energy in Ireland's Schools

ERIC Educational Resources Information Center

Dolan, John

2007-01-01

Since 1998, the Department of Education and Science has been using a process of design, awareness, research and technology known as DART to develop energy efficiency in educational buildings. Currently all primary schools built in accordance with the Department's primary schools technical guidance documents are capable of being up to 2.3 times…

Continuing Challenges and Potential for Collaborative Approaches to Education Reform

ERIC Educational Resources Information Center

Bodilly, Susan J.; Karam, Rita; Orr, Nate

2011-01-01

The Ford Foundation began the Collaborating for Education Reform Initiative (CERI) in 1997-1998 by issuing grants and providing grantees with funds, guidance, and technical assistance to develop collaboratives and carry out activities to improve teaching and learning. CERI's collaborative activities were directed at three possible community…

Theoretical Bases for Using Virtual Reality in Education

ERIC Educational Resources Information Center

Chen, Chwen Jen

2009-01-01

This article elaborates on how the technical capabilities of virtual reality support the constructivist learning principles. It introduces VRID, a model for instructional design and development that offers explicit guidance on how to produce an educational virtual environment. The define phase of VRID consists of three main tasks: forming a…

Technical guidance for assessing phosphorus indices

USDA-ARS?s Scientific Manuscript database

Disparate nutrient and land management recommendations generated by P Indices among states, a perceived lack of change in P-based management, and persistent P loading problems in many of the nation’s waters, led to a revision of the 590 Standard. The revision requires an assessment of P Indices acro...

A GUIDE TO MAPPING INTERTIDAL EELGRASS AND NONVEGETATED HABITATS IN ESTUARIES OF THE PACIFIC NORTHWEST USA

EPA Science Inventory

This document provides technical guidance for planning and implementing the production of aerial photomaps of intertidal vegetative habitats in coastal estuaries of the Pacific Northwest USA (PNW). The focus is on methods of documenting the intertidal distribution of the seagras...

Assessment of need and feasibility of truck-mounted changeable message signs (CMS) for scheduled and unscheduled operations : technical report.

DOT National Transportation Integrated Search

2010-10-01

The goal of this project was to develop implementation guidance that the Texas Department of Transportation : (TxDOT) can use to make better decisions regarding the use of truck mounted changeable message signs : (TMCMS) during scheduled and unschedu...

Making intelligent systems team players: Overview for designers

NASA Technical Reports Server (NTRS)

Malin, Jane T.; Schreckenghost, Debra L.

1992-01-01

This report is a guide and companion to the NASA Technical Memorandum 104738, 'Making Intelligent Systems Team Players,' Volumes 1 and 2. The first two volumes of this Technical Memorandum provide comprehensive guidance to designers of intelligent systems for real-time fault management of space systems, with the objective of achieving more effective human interaction. This report provides an analysis of the material discussed in the Technical Memorandum. It clarifies what it means for an intelligent system to be a team player, and how such systems are designed. It identifies significant intelligent system design problems and their impacts on reliability and usability. Where common design practice is not effective in solving these problems, we make recommendations for these situations. In this report, we summarize the main points in the Technical Memorandum and identify where to look for further information.

Musculoskeletal ultrasound for interventional physiatry.

PubMed

De Muynck, M; Parlevliet, T; De Cock, K; Vanden Bossche, L; Vanderstraeten, G; Özçakar, L

2012-12-01

More and more physiatrists are interested in learning how to use musculoskeletal ultrasonography in their clinical practice. The possibility of high resolution, dynamic, comparative and repeatable imaging makes it an important diagnostic tool for soft tissue pathology. There is also growing interest to use sonography for guiding interventions such as aspirations and infiltrations. In daily practice these are often done blindly or palpation-guided. To improve the accuracy of interventions, fluoroscopy or computed tomography were traditionally used for guidance. Since sonography is non-ionizing, readily available and relatively low cost, it has become the first choice to guide many musculoskeletal interventions. Ultrasound allows real-time imaging of target and needle as well as surrounding vulnerable structures such as vessels and nerves. Many different techniques are proposed in the literature. Interventions under ultrasound guidance have been proven to be more accurate than unguided ones. Further studies are required to prove better clinical results and fewer complications. Infection is the most dreaded complication. This review wants to highlight technical aspects of ultrasound guidance of interventions and give a survey of different interventions that have been introduced, with emphasis on applications in Physical Medicine and Rehabilitation. Results and complications are discussed. Finally training requirements and modalities are presented.

UK quantitative WB-DWI technical workgroup: consensus meeting recommendations on optimisation, quality control, processing and analysis of quantitative whole-body diffusion-weighted imaging for cancer.

PubMed

Barnes, Anna; Alonzi, Roberto; Blackledge, Matthew; Charles-Edwards, Geoff; Collins, David J; Cook, Gary; Coutts, Glynn; Goh, Vicky; Graves, Martin; Kelly, Charles; Koh, Dow-Mu; McCallum, Hazel; Miquel, Marc E; O'Connor, James; Padhani, Anwar; Pearson, Rachel; Priest, Andrew; Rockall, Andrea; Stirling, James; Taylor, Stuart; Tunariu, Nina; van der Meulen, Jan; Walls, Darren; Winfield, Jessica; Punwani, Shonit

2018-01-01

Application of whole body diffusion-weighted MRI (WB-DWI) for oncology are rapidly increasing within both research and routine clinical domains. However, WB-DWI as a quantitative imaging biomarker (QIB) has significantly slower adoption. To date, challenges relating to accuracy and reproducibility, essential criteria for a good QIB, have limited widespread clinical translation. In recognition, a UK workgroup was established in 2016 to provide technical consensus guidelines (to maximise accuracy and reproducibility of WB-MRI QIBs) and accelerate the clinical translation of quantitative WB-DWI applications for oncology. A panel of experts convened from cancer centres around the UK with subspecialty expertise in quantitative imaging and/or the use of WB-MRI with DWI. A formal consensus method was used to obtain consensus agreement regarding best practice. Questions were asked about the appropriateness or otherwise on scanner hardware and software, sequence optimisation, acquisition protocols, reporting, and ongoing quality control programs to monitor precision and accuracy and agreement on quality control. The consensus panel was able to reach consensus on 73% (255/351) items and based on consensus areas made recommendations to maximise accuracy and reproducibly of quantitative WB-DWI studies performed at 1.5T. The panel were unable to reach consensus on the majority of items related to quantitative WB-DWI performed at 3T. This UK Quantitative WB-DWI Technical Workgroup consensus provides guidance on maximising accuracy and reproducibly of quantitative WB-DWI for oncology. The consensus guidance can be used by researchers and clinicians to harmonise WB-DWI protocols which will accelerate clinical translation of WB-DWI-derived QIBs.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goltz, Jan P., E-mail: Goltz@roentgen.uni-wuerzburg.de; Scholl, Anne; Ritter, Christian O.

The aim of this study is to evaluate the effectiveness and safety of percutaneously placed totally implantable venous-access ports (TIVAPs) of the forearm. Between January 2006 and October 2008, peripheral TIVAPs were implanted in 763 consecutive patients by ultrasound and fluoroscopic guidance. All catheters were implanted under local anesthesia and were tunneled subcutaneously. Indication, technical success, and complications were retrospectively analyzed according to Society of Interventional Radiology (SIR) criteria. Presence of antibiotic prophylaxis, periprocedurally administered drugs (e.g., sedation), and laboratory results at the time of implantation were analyzed. Maintenance during the service interval was evaluated. In total, 327,499 catheter-days weremore » analyzed. Technical success rate was 99.3%. Reasons for initial failure of implantation were either unexpected thrombosis of the subclavian vein, expanding tumor mass of the mediastinum, or failure of peripheral venous access due to fragile vessels. Mean follow-up was 430 days. There were 115 complications observed (15.1%, 0.03 per 100 catheter-days), of which 33 (4.3%) were classified as early (within 30 days from implantation) and 82 (10.7%) as late. Catheter-related venous thrombosis was found in 65 (8.5%) of 763 (0.02 per 100 catheter-days) TIVAPs. Infections were observed in 41 (5.4%) of 763 (0.01 per 100 catheter-days) devices. Other complications observed included dislocation of the catheter tip (0.8%), occlusion (0.1%), or rupture (0.1%) of the port catheter. Dislocated catheters were corrected during a second interventional procedure. In conclusion, implantation of percutaneously placed peripheral TIVAPs shows a high technical success rate and low risk of early complications when ultrasound and fluoroscopic guidance are used. Late complications are observed three times as often as early complications.« less

Monitored Natural Attenuation as a Remediation Strategy for Nuclear Power Plant Applications

NASA Astrophysics Data System (ADS)

Kim, K.; Bushart, S.

2009-12-01

A NRC Information Notice (IN 2006-13) was produced to inform holders of nuclear operating licenses “of the occurrence of radioactive contamination of ground water at multiple facilities due to undetected leakage from facility structures, systems, or components (SSCs) that contain or transport radioactive fluids” so that they could consider actions, as appropriate, to avoid similar problems. To reinforce their commitment to environmental stewardship the nuclear energy industry has committed to improving management of situations that have the potential to lead to the inadvertent release of radioactive fluids. This Industry Groundwater Protection Initiative, finalized in June 2007 as [NEI 07-07], calls for implementation and improvement of on-site groundwater monitoring programs and enhanced communications with stakeholders and regulators about situations related to inadvertent releases. EPRI developed its Groundwater Protection Program to provide the nuclear energy industry with the technical support needed to implement the Industry Groundwater Initiative. An objective of the EPRI Groundwater Protection Program is to provide the nuclear industry with technically sound guidance for implementing and enhancing on-site groundwater monitoring programs. EPRI, in collaboration with the EPRI Groundwater Protection Committee of utility members, developed the EPRI Groundwater Protection Guidelines for Nuclear Power Plants (EPRI Report 1015118, November 2007), which provides site-specific guidance for implementing a technically sound groundwater monitoring program. The guidance applies a graded approach for nuclear plants to tailor a technically effective and cost efficient groundwater monitoring program to the site’s hydrogeology and risk for groundwater contamination. As part of the Groundwater Protection Program, EPRI is also investigating innovative remediation technologies for addressing low-level radioactive contamination in soils and groundwater at nuclear power plant sites. One of these remediation technologies is monitored natural attenuation (MNA), which has been widely used in other industries for the remediation of contaminants in soil and groundwater. Monitored natural attenuation (MNA) is a non-intervention, but not a no-action, groundwater and soil remediation approach that involves monitoring the dilution, dispersion, and decay of contaminants to meet remediation objectives. MNA has been commonly applied at sites where soil and groundwater have been contaminated by volatile organic compounds. This method has also been applied to remediation of radiological contamination at U.S. DOE facilities and decommissioning nuclear power plant sites. The EPRI published report (1016764) provides guidance for implementing MNA at nuclear power plants for remediation of radiological contaminants in groundwater and soil. The goal of the EPRI Groundwater Protection program is to bring together experience and technologies - both from within the nuclear industry and other industries - to support the industry’s commitment to environmental stewardship. Results from the program are being published in an extensive series of reports and software, and are being communicated to members in an annual EPRI Groundwater Protection technical exchange workshop.

International commitments and guidance on unsafe abortion.

PubMed

Sai, Fred

2004-04-01

Most of Africa's 54 countries have restrictive abortion laws, outdated remnants of former colonial laws that result in nearly five million unsafe abortions annually. To stem maternal mortality and morbidity, it is essential to look beyond strictly medical or health system approaches to solving this critical public health problem. The issue must be approached from a human rights perspective that emphasises the individual's right to self-determination. This article examines ways in which advocates can use established human rights standards, international consensus documents, and the World Health Organization's new technical and policy guidance for health systems to press for safer abortion care for African women.

Manual of Documentation Practices Applicable to Defence-Aerospace Scientific and Technical Information. Volume 3. Section 7 - Information Retrieval. Section 8 - Dissemination Practices. Section 9 - Microform Systems and Reprography

DTIC Science & Technology

1980-10-01

Location Flowchart has been drawn up to give guidance as to where to apply for various categories of reports. It also serves as an aid in deciding whether...or further disclosure S.l-. 72 NOTES 1. The flowchart is not intended to cover all possibilities; the following points are made for your guidance. 2...not followed the flowchart correctly - start again from ’BEGIN’. NEI N ’"A. 7-.1 %. 73 REPORT LOCATION BEGIN~ FLOWCHART rreporto aD-P.orriBR6N~I-D ubr

Modeling pilot interaction with automated digital avionics systems: Guidance and control algorithms for contour and nap-of-the-Earth flight

NASA Technical Reports Server (NTRS)

Hess, Ronald A.

1990-01-01

A collection of technical papers are presented that cover modeling pilot interaction with automated digital avionics systems and guidance and control algorithms for contour and nap-of-the-earth flight. The titles of the papers presented are as follows: (1) Automation effects in a multiloop manual control system; (2) A qualitative model of human interaction with complex dynamic systems; (3) Generalized predictive control of dynamic systems; (4) An application of generalized predictive control to rotorcraft terrain-following flight; (5) Self-tuning generalized predictive control applied to terrain-following flight; and (6) Precise flight path control using a predictive algorithm.

Technical Assistance From State Health Departments for Communities Engaged in Policy, Systems, and Environmental Change: The ACHIEVE Program

PubMed Central

Hefelfinger, Jenny; Patty, Alice; Ussery, Ann

2013-01-01

Introduction This study assessed the value of technical assistance provided by state health department expert advisors and by the staff of the National Association of Chronic Disease Directors (NACDD) to community groups that participated in the Action Communities for Health, Innovation, and Environmental Change (ACHIEVE) Program, a CDC-funded health promotion program. Methods We analyzed quantitative and qualitative data reported by community project coordinators to assess the nature and value of technical assistance provided by expert advisors and NACDD staff and the usefulness of ACHIEVE resources in the development and implementation of community action plans. A grounded theory approach was used to analyze and categorize phrases in text data provided by community coordinators. Open coding placed conceptual labels on text phrases. Frequency distributions of the quantitative data are described and discussed. Results The most valuable technical assistance and program support resources were those determined to be in the interpersonal domain (ie, interactions with state expert advisors, NACDD staff, and peer-to-peer support). The most valuable technical assistance events were action institutes, coaches’ meetings, webinars, and technical assistance conference calls. Conclusion This analysis suggests that ACHIEVE communities valued the management and training assistance provided by expert advisors and NACDD staff. State health department expert advisors provided technical guidance and support, including such skills or knowledge-based services as best-practice strategies, review and discussion of community assessment data, sustainability planning, and identification of possible funding opportunities. NACDD staff led development and implementation of technical assistance events. PMID:24157078

Descriptive Cadaveric Study Comparing the Accuracy of Ultrasound Versus Fluoroscopic Guidance for First Sacral Transforaminal Injections: A Comparison Study.

PubMed

Thompson, Bradley F; Pingree, Matthew J; Qu, Wenchun; Murthy, Naveen S; Lachman, Nirusha; Hurdle, Mark Friedrich

2018-04-01

Ultrasound is rarely used for guiding lumbosacral epidural steroid injections due to its technical limitations. For example, sonographic imaging lacks the ability to confirm epidural spread and identify vascular uptake. The perceived risk that these limitations pose to human subjects has precluded any large scale clinical trials to date. To compare the accuracy of ultrasound versus fluoroscopic guidance for first sacral transforaminal epidural injections. Cadaveric comparative study using dichotomous outcomes. A fluoroscopy suite and anatomic laboratory at an academic medical center. Four unembalmed adult human cadavers with no history of spinal surgery. Eight sites were injected twice by one interventionalist, using fluoroscopic and ultrasound guidance. In the fluoroscopy arm, contrast spread was assessed using computed tomography. In the ultrasound arm, latex spread was assessed using gross anatomic dissection. Any visible evidence of epidural spread constituted a positive result. Comparison of the success of obtaining epidural contrast flow was the primary outcome measure. Secondary outcome measures included average duration, rate of intravascular uptake, and quantity of intravascular uptake. All injections performed in both the ultrasound arm and the fluoroscopy arm had positive epidural spread. The average duration was 3.03 minutes with fluoroscopy and 4.76 minutes with ultrasound. The rate of intravascular uptake was 37.5% with fluoroscopy and 50% with ultrasound. Within the ultrasound arm, greater intravascular spread and duration variability were recorded. Although ultrasonography can provide reliable image guidance for cannulating the first sacral foramen in cadavers, it would have limited clinical utility due to its inability to visualize relevant neurovascular structures deep to the osseus roof and exclude intravascular uptake. IV. Copyright © 2018 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

Revisions to US EPA Superfund Risk and Dose Assessment Models and Guidance - 13403

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walker, Stuart A.

2013-07-01

The U.S. Environmental Protection Agency (EPA) Superfund program's six Preliminary Remediation Goal (PRG) and Dose Compliance Concentration (DCC) internet based calculators for risk and dose assessment at Superfund sites are being revised to reflect better science, revisions to existing exposure scenarios and new scenarios, and changes to match up more closely with the EPA chemical regional screening level calculator. A revised version of the 1999 guidance document that provides an overview for the Superfund risk assessment process at radioactively contaminated sites, 'Radiation Risk Assessment At CERCLA Sites: Q and A', is being completed that will reflect Superfund recommended guidance andmore » other technical documents issued over the past 13 years. EPA is also issuing a series of fact sheets in the document 'Superfund Radiation Risk Assessment: A Community Tool-kit'. This presentation would go over those changes that are expected to be finished by this spring. (authors)« less

Technical evaluation of RETS-required reports for Browns Ferry Nuclear Power Station, Units 1, 2, and 3, for 1983

DOE Office of Scientific and Technical Information (OSTI.GOV)

Young, T.E.; Magleby, E.H.

1985-09-06

A review was performed of reports required by federal regulations and the plant-specific radiological effluent technical specifications (RETS) for operations conducted at Tennessee Valley Authority's Browns Ferry Nuclear Station, Units 1, 2, and 3, during 1983. The two periodic reports reviewed were (a) the Effluents and Waste Disposal Semiannual Report, First Half 1983 and (b) the Effluents and Waste Disposal Semiannual Report, Second Half 1983. The principal review guidelines were the plant's specific RETs and NRC guidance given in NUREG-0133, ''Preparation of Radiological Effluent Technical Specifications for Nuclear Power Plants.'' The Licensee's submitted reports were found to be reasonably completemore » and consistent with the review guidelines.« less

Feasibility of three-dimensional magnetic resonance angiography-fluoroscopy image fusion technique in guiding complex endovascular aortic procedures in patients with renal insufficiency.

PubMed

Schwein, Adeline; Chinnadurai, Ponraj; Shah, Dipan J; Lumsden, Alan B; Bechara, Carlos F; Bismuth, Jean

2017-05-01

Three-dimensional image fusion of preoperative computed tomography (CT) angiography with fluoroscopy using intraoperative noncontrast cone-beam CT (CBCT) has been shown to improve endovascular procedures by reducing procedure length, radiation dose, and contrast media volume. However, patients with a contraindication to CT angiography (renal insufficiency, iodinated contrast allergy) may not benefit from this image fusion technique. The primary objective of this study was to evaluate the feasibility of magnetic resonance angiography (MRA) and fluoroscopy image fusion using noncontrast CBCT as a guidance tool during complex endovascular aortic procedures, especially in patients with renal insufficiency. All endovascular aortic procedures done under MRA image fusion guidance at a single-center were retrospectively reviewed. The patients had moderate to severe renal insufficiency and underwent diagnostic contrast-enhanced magnetic resonance imaging after gadolinium or ferumoxytol injection. Relevant vascular landmarks electronically marked in MRA images were overlaid on real-time two-dimensional fluoroscopy for image guidance, after image fusion with noncontrast intraoperative CBCT. Technical success, time for image registration, procedure time, fluoroscopy time, number of digital subtraction angiography (DSA) acquisitions before stent deployment or vessel catheterization, and renal function before and after the procedure were recorded. The image fusion accuracy was qualitatively evaluated on a binary scale by three physicians after review of image data showing virtual landmarks from MRA on fluoroscopy. Between November 2012 and March 2016, 10 patients underwent endovascular procedures for aortoiliac aneurysmal disease or aortic dissection using MRA image fusion guidance. All procedures were technically successful. A paired t-test analysis showed no difference between preimaging and postoperative renal function (P = .6). The mean time required for MRA-CBCT image fusion was 4:09 ± 01:31 min:sec. Total fluoroscopy time was 20.1 ± 6.9 minutes. Five of 10 patients (50%) underwent stent graft deployment without any predeployment DSA acquisition. Three of six vessels (50%) were cannulated under image fusion guidance without any precannulation DSA runs, and the remaining vessels were cannulated after one planning DSA acquisition. Qualitative evaluation showed 14 of 22 virtual landmarks (63.6%) from MRA overlaid on fluoroscopy were completely accurate, without the need for adjustment. Five of eight incorrect virtual landmarks (iliac and visceral arteries) resulted from vessel deformation caused by endovascular devices. Ferumoxytol or gadolinium-enhanced MRA imaging and image fusion with fluoroscopy using noncontrast CBCT is feasible and allows patients with renal insufficiency to benefit from optimal guidance during complex endovascular aortic procedures, while preserving their residual renal function. Copyright © 2016 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

Technical Guidance for Conducting ASVAB Validation/Standards Studies in the U.S. Navy

DTIC Science & Technology

2015-02-01

the criterion), we can compute the variance of X in the unrestricted group, 2xS , and in the restricted (selected) group, 2 xs . 3 In contrast, we...well as the selected group, 2 xs . We also know the variance of Y in the selected group, 2ys , and the correlation of X and Y in the selected...and AS. Five levels of selection ratio (1.0, .8, .6, .4, and .2) and eight sample sizes (50, 75, 100, 150, 225, 350 , 500, and 800) were considered

Peer Learning Community Guide. CEELO FastFact

ERIC Educational Resources Information Center

Schilder, Diane; Brown, Kirsty Clarke; Gillaspy, Kathi

2014-01-01

States and technical assistance centers have asked the Center on Enhancing Early Learning Outcomes (CEELO) for guidance on establishing and maintaining a peer learning community (PLC). This document is designed to delineate the steps to establish and sustain a Peer Learning Community (PLC). It begins with a definition of a PLC and then presents…

77 FR 429 - Clarification and Further Guidance on the Fireworks Approvals Policy

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-05

...) and the American Pyrotechnic Association (APA) Standard 87-1. PHMSA understands that it is a common... approval is requested conforms to the APA Standard 87-1, and the descriptions and technical information... manufacturer must sign and certify that the device for which the approval is requested conforms to the APA...

A Survey of Private Ohio Academic Libraries' Physical Processing Practices for Circulating Books.

ERIC Educational Resources Information Center

Factor, Olivia Spaid

Little guidance is given in today's general technical services or cataloging textbooks to assist librarians in making decisions on procedures for the physical preparation of materials prior to placement on the shelves for public access. As small, private academic libraries face automation of circulation, addition of security systems, and debates…

76 FR 64399 - Advisory Committee on Reactor Safeguards; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-18

... Thursday, October 21, 2010 (74 FR 65038-65039). Thursday, November 3, 2011, Conference Room T2-B1, 11545... Evaluation of Diversity and Defense-In-Depth in Digital Computer-Based Instrumentation and Control Systems... staff regarding Branch Technical Position 7- 19, ``Guidance for the Evaluation of Diversity and Defense...

Administration and Research of Competency-/Performance-Based Teacher Education Programs.

ERIC Educational Resources Information Center

Trzasko, Joseph A.

This paper describes the proposed Assessment Center at Mercy College in Dobbs Ferry, New York. The center is intended to provide statistical and technical support for the Mercy College elementary education, special education, and speech and hearing departments in the areas of student assessment, student guidance, and program evaluation. Evaluation…

A Framework for the Development of Computerized Adaptive Tests

ERIC Educational Resources Information Center

Thompson, Nathan A.; Weiss, David J.

2011-01-01

A substantial amount of research has been conducted over the past 40 years on technical aspects of computerized adaptive testing (CAT), such as item selection algorithms, item exposure controls, and termination criteria. However, there is little literature providing practical guidance on the development of a CAT. This paper seeks to collate some…

Guidelines for qualifying cleaning and verification materials

NASA Technical Reports Server (NTRS)

Webb, D.

1995-01-01

This document is intended to provide guidance in identifying technical issues which must be addressed in a comprehensive qualification plan for materials used in cleaning and cleanliness verification processes. Information presented herein is intended to facilitate development of a definitive checklist that should address all pertinent materials issues when down selecting a cleaning/verification media.

An application of importance-performance analysis to recreational storm chasing

Treesearch

Jiawen Chen; Sonja Wilhelm Stanis; Carla Barbieri; Shuangyu Xu

2012-01-01

Since the release of the movie "Twister" in 1996, storm chasing has become an increasingly popular form of recreation. Storm chasing tour agencies have emerged to provide technical assistance and guidance to individuals wishing to participate in this activity. However, little is known about the participants' perceptions of their storm chasing tours....

COUNSELING THE TECHNICALLY-ORIENTED STUDENT.

ERIC Educational Resources Information Center

Ferris State Coll., Big Rapids, MI.

IN 1967, A SELECTED GROUP OF MICHIGAN SECONDARY SCHOOL COUNSELORS PARTICIPATED IN A WORKSHOP DESIGNED TO PROVIDE--(1) AN OVERVIEW OF THE ROLE OF TECHNICIANS IN MODERN BUSINESS AND INDUSTRY, (2) CURRENT DATA ON THE NEEDS FOR TRAINED TECHNICIANS, (3) AN OPPORTUNITY TO REVIEW TECHNIQUES OF VOCATIONAL COUNSELING AND GUIDANCE AS THEY RELATE TO STUDENTS…

Securing Equal Educational Opportunity: Report to the President and Secretary of Education, Fiscal Year 2016

ERIC Educational Resources Information Center

Office for Civil Rights, US Department of Education, 2016

2016-01-01

In FY 2016, the Office for Civil Rights (OCR) promoted equity and excellence in education through conducting investigations and monitoring schools under resolution agreements, promoting greater understanding of how OCR interprets and enforces civil rights laws through the release of policy guidance, providing technical assistance and outreach to…

School-Based Primary School Sexuality Education for Migrant Children in Beijing, China

ERIC Educational Resources Information Center

Liu, Wenli; Su, Yufen

2014-01-01

In May 2007, Beijing Normal University launched a programme of school-based sexuality education for migrant children in Xingzhi Primary School in Beijing. Over the past seven years, the project team has developed a school-based sexuality education curriculum using the "International Technical Guidance on Sexuality Education" published by…

78 FR 59654 - Possible Models for the Administration and Support of Discipline-Specific Guidance Groups for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-27

... science by improving coordination across a broad range of forensic science disciplines. The new initiative... intended to provide structured forums for the exchange of ideas among operational, technical, research, and... needs of forensic science research and measurement standards, and verifying the scientific basis exists...

75 FR 54918 - Draft Regulatory Guide, DG-1247, “Design-Basis Hurricane and Hurricane Missiles for Nuclear Power...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-09

... that the staff uses in evaluating specific problems or postulated accidents, and data that the staff... turbine missiles. NUREG/CR 7004 is the technical basis for regulatory guidance on design-basis hurricane... hurricane wind speeds for new nuclear power plants. [[Page 54919

Overview and application of the Continuous-Flow Traffic Time-Integrated Method (CTIM) for determining the influence of road surfaces on traffic noise

DOT National Transportation Integrated Search

2012-08-19

The U.S. Department of Transportation Federal Highway Administration is sponsoring a Technical Working Group (TWG) to develop guidance for measuring the influence of road surfaces on tire-pavement noise, vehicle noise, and traffic noise in the U.S. T...

Who Am I? Self-Exploration Series 1. Courseware Evaluation for Vocational and Technical Education.

ERIC Educational Resources Information Center

Miller, Sandra; And Others

This courseware evaluation rates the Who Am I? program developed by Instructional Enterprises. (This program--not contained in this document--is an interactive guidance course including four inventories students use to learn more about themselves.) Part A describes the program in terms of subject area (personal development) and hardware…

Technical Assistance for Tribes | State, Local, and Tribal Governments |

Science.gov Websites

credible research and analytics to identify impactful opportunities for clean energy development on tribal and engineering research with tribal governments to directly access the benefits of clean energy for technologies. Look for examples of NREL work on the DOE Office of Indian Energy blog. For guidance on tribal

7 CFR 245.6 - Application, eligibility and certification of children for free and reduced price meals and free...

Code of Federal Regulations, 2010 CFR

2010-01-01

...) General requirements—content of application and descriptive materials. Each local educational agency, as... to the distribution of applications and descriptive materials in paper form as provided for in this... requirements in this section and with technical assistance and guidance provided by FNS. Descriptive materials...

7 CFR 245.6 - Application, eligibility and certification of children for free and reduced price meals and free...

Code of Federal Regulations, 2011 CFR

2011-01-01

...) General requirements—content of application and descriptive materials. Each local educational agency, as... to the distribution of applications and descriptive materials in paper form as provided for in this... requirements in this section and with technical assistance and guidance provided by FNS. Descriptive materials...

GUIDANCE MANUAL FOR THE PREPARATION OF DEMONSTRATION AND QUALITY ASSURANCE PROJECT PLANS FOR THE VERIFICATION OF FIELD CHARACTERIZATION AND MONITORING TECHNOLOGIES

EPA Science Inventory

This work represents the technical and editorial contributions of a large number of U.S. Environmental Protection Agency (EPA) employees and others familiar with or interested in the demonstration and evaluation of innovative site characterization and monitoring technologies. In ...

Geospatial Engineering

DTIC Science & Technology

2017-02-22

manages operations through guidance, policies, programs, and organizations. The NSG is designed to be a mutually supportive enterprise that...deliberate technical design and deliberate human actions. Geospatial engineer teams (GETs) within the geospatial intelligence cells are the day-to-day...standards working group and are designated by the AGC Geospatial Acquisition Support Directorate as required for interoperability. Applicable standards

78 FR 31922 - National Environmental Justice Advisory Council; Notification of Public Teleconference Meeting...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-28

... draft Technical Guidance for Assessing Environmental Justice in Regulatory Analysis. There will be a... public comment period, or to submit written public comments, is also Noon, Monday, June 10, 2013. DATES... like to be put on the list to provide public comment, and whether you are submitting written comments...

Electromagnetic Radiation Hazards Testing for Non-Ionizing Radio Frequency Transmitting Equipment

DTIC Science & Technology

2012-12-19

Hazards of Electromagnetic Radiation to Ordnance (HERO), Personnel (HERP), and Fuel (HERF) protection guidance for intentional non-ionizing Radio...HERO Hazards of Electromagnetic Radiation to Ordnance HERP Hazards of Electromagnetic Radiation to Personnel IEEE Institute of Electrical and...Systems Command Technical Manual, Electromagnetic Radiation Hazards ( Hazards to Ordnance ), 1 July 2008.

77 FR 43405 - Final Standard Review Plan, Branch Technical Position 7-19 on Guidance for Evaluation of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-24

... Digital Computer-Based Instrumentation and Control Systems.'' This BTP is to be cited as the acceptance criteria for Diversity and Defense-in-Depth in Digital Computer-Based Instrumentation and Control Systems... Evaluation of Diversity and Defense-in-Depth in Digital Computer-Based Instrumentation and Control Systems...

Essentials of Career Interest Assessment. Essentials of Psychological Assessment Series.

ERIC Educational Resources Information Center

Prince, Jeffrey P.; Heiser, Lisa J.

This book is a quick reference source to guide the career professional through the essentials of using the most popular career interest tools. It summarizes important technical aspects of each inventory, and offers step-by-step guidance in the interpretation and use of the various inventories. The chapters are: (1) "Overview"; (2)…

DEVELOPMENT AND AVAILABILITY OF EQUILIBRIUM PARTITIONING SEDIMENT GUIDELINES (ESGS) FOR NONIONIC ORGANIC CONTAMINANTS, METALS MIXTURES, AND POLYCYCLIC AROMATIC HYDROCARBON (PAH) MIXTURES

EPA Science Inventory

Collaborative efforts between EPA's Office of Water and Office of Research and Development have resulted in the development of sediment guidelines based on equilibrium partitioning theory (EqP). The guidance available includes a technical support document, describing the derivat...

Computer Security and the Data Encryption Standard. Proceedings of the Conference on Computer Security and the Data Encryption Standard.

ERIC Educational Resources Information Center

Branstad, Dennis K., Ed.

The 15 papers and summaries of presentations in this collection provide technical information and guidance offered by representatives from federal agencies and private industry. Topics discussed include physical security, risk assessment, software security, computer network security, and applications and implementation of the Data Encryption…

NREL: U.S. Life Cycle Inventory Database - Advisory Committee

Science.gov Websites

Advisory Committee The U.S. Life Cycle Inventory (LCI) Database established an advisory committee to provide technical and financial guidance to the NREL database management team. The committee will Assessing and responding to user feedback to ensure that the database meets the needs of data providers

Development and Evaluation of a Vocational Experience Curriculum for Educable and Disadvantaged Students. Final Report.

ERIC Educational Resources Information Center

Hardin County Board of Education, Elizabethtown, KY.

A project was designed to measure the effects of integrating basic reading and mathematical instruction with prevocational instruction through the addition of a basic skills resource room, a technical simulation unit, and guidance and counseling to the ninth grade vocational experience program for educable mentally handicapped and disadvantaged…

Understanding Variation in Treatment Effects in Education Impact Evaluations: An Overview of Quantitative Methods. NCEE 2014-4017

ERIC Educational Resources Information Center

Schochet, Peter Z.; Puma, Mike; Deke, John

2014-01-01

This report summarizes the complex research literature on quantitative methods for assessing how impacts of educational interventions on instructional practices and student learning differ across students, educators, and schools. It also provides technical guidance about the use and interpretation of these methods. The research topics addressed…