Input impedance of a probe-fed circular microstrip antenna with thick substrate

NASA Technical Reports Server (NTRS)

Davidovitz, M.; Lo, Y. T.

1986-01-01

A method of computing the input impedance for the probe fed circular microstrip antenna with thick dielectric substrate is presented. Utilizing the framework of the cavity model, the fields under the microstrip patch are expanded in a set of modes satisfying the boundary conditions on the eccentrically located probe, as well as on the cavity magnetic wall. A mode-matching technique is used to solve for the electric field at the junction between the cavity and the coaxial feed cable. The reflection coefficient of the transverse electromagnetic (TEM) mode incident in the coaxial cable is determined, from which the input impedance of the antenna is computed. Measured data are presented to verify the theoretical calculations. Results of the computation of various losses for the circular printed antenna as a function of substrate thickness are also included.

High Precision Linear And Circular Polarimetry. Sources With Stable Stokes Q,U & V In The Ghz Regime

NASA Astrophysics Data System (ADS)

Myserlis, Ioannis; Angelakis, E.; Zensus, J. A.

2017-10-01

We present a novel data analysis pipeline for the reconstruction of the linear and circular polarization parameters of radio sources. It includes several correction steps to minimize the effect of instrumental polarization, allowing the detection of linear and circular polarization degrees as low as 0.3 %. The instrumental linear polarization is corrected across the whole telescope beam and significant Stokes Q and U can be recovered even when the recorded signals are severely corrupted. The instrumental circular polarization is corrected with two independent techniques which yield consistent Stokes V results. The accuracy we reach is of the order of 0.1-0.2 % for the polarization degree and 1\\u00ba for the angle. We used it to recover the polarization of around 150 active galactic nuclei that were monitored monthly between 2010.6 and 2016.3 with the Effelsberg 100-m telescope. We identified sources with stable polarization parameters that can be used as polarization standards. Five sources have stable linear polarization; three are linearly unpolarized; eight have stable polarization angle; and 11 sources have stable circular polarization, four of which with non-zero Stokes V.

A Sensitivity Analysis of Circular Error Probable Approximation Techniques

DTIC Science & Technology

1992-03-01

SENSITIVITY ANALYSIS OF CIRCULAR ERROR PROBABLE APPROXIMATION TECHNIQUES THESIS Presented to the Faculty of the School of Engineering of the Air Force...programming skills. Major Paul Auclair patiently advised me in this endeavor, and Major Andy Howell added numerous insightful contributions. I thank my...techniques. The two ret(st accuratec techniiques require numerical integration and can take several hours to run ov a personal comlputer [2:1-2,4-6]. Some

UV-CD12: synchrotron radiation circular dichroism beamline at ANKA

PubMed Central

Bürck, Jochen; Roth, Siegmar; Windisch, Dirk; Wadhwani, Parvesh; Moss, David; Ulrich, Anne S.

2015-01-01

Synchrotron radiation circular dichroism (SRCD) is a rapidly growing technique for structure analysis of proteins and other chiral biomaterials. UV-CD12 is a high-flux SRCD beamline installed at the ANKA synchrotron, to which it had been transferred after the closure of the SRS Daresbury. The beamline covers an extended vacuum-UV to near-UV spectral range and has been open for users since October 2011. The current end-station allows for temperature-controlled steady-state SRCD spectroscopy, including routine automated thermal scans of microlitre volumes of water-soluble proteins down to 170 nm. It offers an excellent signal-to-noise ratio over the whole accessible spectral range. The technique of oriented circular dichroism (OCD) was recently implemented for determining the membrane alignment of α-helical peptides and proteins in macroscopically oriented lipid bilayers as mimics of cellular membranes. It offers improved spectral quality <200 nm compared with an OCD setup adapted to a bench-top instrument, and accelerated data collection by a factor of ∼3. In addition, it permits investigations of low hydrated protein films down to 130 nm using a rotatable sample cell that avoids linear dichroism artifacts. PMID:25931105

SINGLE STRAND-CONTAINING REPLICATING MOLECULES OF CIRCULAR MITOCHONDRIAL DNA

PubMed Central

Wolstenholme, David R.; Koike, Katsuro; Cochran-Fouts, Patricia

1973-01-01

Mitochondrial DNAs (mtDNAs) from Chang rat solid hepatomas and Novikoff rat ascites hepatomas were examined in the electron microscope after preparation by the aqueous and by the formamide protein monolayer techniques. MtDNAs from both tumors were found to include double-forked circular molecules with a form and size suggesting they were replicative intermediates. These molecules were of two classes. In molecules of one class, all three segments were apparently totally double stranded. Molecules of the second class were distinguished by the fact that one of the segments spanning the region between the forks in which replication had occurred (the daughter segments) was either totally single stranded, or contained a single-stranded region associated with one of the forks. Daughter segments of both totally double-stranded and single strand-containing replicating molecules varied in length from about 3 to about 80% of the circular contour length of the molecule. Similar classes of replicating molecules were found in mtDNA from regenerating rat liver and chick embryos, indicating them to be normal intermediates in the replication of mtDNA All of the mtDNAs examined included partially single-stranded simple (nonforked) circular molecules. A possible scheme for the replication of mtDNA is presented, based on the different molecular forms observed PMID:4345165

Assignment of absolute stereostructures through quantum mechanics electronic and vibrational circular dichroism calculations.

PubMed

Dai, Peng; Jiang, Nan; Tan, Ren-Xiang

2016-01-01

Elucidation of absolute configuration of chiral molecules including structurally complex natural products remains a challenging problem in organic chemistry. A reliable method for assigning the absolute stereostructure is to combine the experimental circular dichroism (CD) techniques such as electronic and vibrational CD (ECD and VCD), with quantum mechanics (QM) ECD and VCD calculations. The traditional QM methods as well as their continuing developments make them more applicable with accuracy. Taking some chiral natural products with diverse conformations as examples, this review describes the basic concepts and new developments of QM approaches for ECD and VCD calculations in solution and solid states.

Analysis of laser light-scattering interferometric devices for in-line diagnostics of moving particles

NASA Astrophysics Data System (ADS)

Naqwi, Amir A.; Durst, Franz

1993-07-01

Dual-beam laser measuring techniques are now being used, not only for velocimetry, but also for simultaneous measurements of particle size and velocity in particulate two-phase flows. However, certain details of these optical techniques, such as the effect of Gaussian beam profiles on the accuracy of the measurements, need to be further explored. To implement innovative improvements, a general analytic framework is needed in which performances of various dual-beam instruments could be quantitatively studied and compared. For this purpose, the analysis of light scattering in a generalized dual-wave system is presented in this paper. The present simulation model provides a basis for studying effects of nonplanar beam structures of incident waves, taking into account arbitrary modes of polarization. A polarizer is included in the receiving optics as well. The peculiar aspects of numerical integration of scattered light over circular, rectangular, and truncated circular apertures are also considered.

Reynolds stress closure in jet flows using wave models

NASA Technical Reports Server (NTRS)

Morris, Philip J.

1990-01-01

A collection of papers is presented. The outline of this report is as follows. Chapter three contains a description of a weakly nonlinear turbulence model that was developed. An essential part of the application of such a closure scheme to general geometry jets is the solution of the local hydrodynamic stability equation for a given jet cross-section. Chapter four describes the conformal mapping schemes used to map such geometries onto a simple computational domain. Chapter five describes a solution of a stability problem for circular, elliptic, and rectangular geometries. In chapter six linear models for the shock shell structure in non-circular jets is given. The appendices contain reprints of papers also published during this study including the following topics: (1) instability of elliptic jets; (2) a technique for predicting the shock cell structure in non-circular jets using a vortex sheet model; and (3) the resonant interaction between twin supersonic jets.

Circular stapler introducer: a novel device to facilitate stapled colorectal anastomosis.

PubMed

Guweidhi, Ahmed; Steffen, Rudolf; Metzger, Alejandro; Teuscher, Jürg; Flückiger, Petra; Z'graggen, Kaspar

2009-04-01

A circular stapler introducer was developed to protect the head of the circular stapler and enable atraumatic introduction and advancement of the circular stapler without interfering with the application and safety of an anastomosis. In a Phase I prospective study, we tested the feasibility and safety of the novel circular stapler introducer device in 60 consecutive patients undergoing left-sided colorectal resections. The median distance of the anastomoses from the anal verge was 12 cm (7-20, n = 60). Total morbidity was 15 percent. No mortality was observed. Handling of the circular stapler introducer was considered nonproblematic by all surgeons who participated in the study. No interference of the circular stapler introducer with the circular stapling devices used was encountered. The advancement of the stapler into the end of the colorectal stump was always possible with the aid of the circular stapler introducer. Use of the circular stapler introducer facilitates the double-stapling technique of colorectal anastomosis. The circular stapler introducer has great potential and should be tested in larger studies.

Circular Dichroism of G-Quadruplex: A Laboratory Experiment for the Study of Topology and Ligand Binding

ERIC Educational Resources Information Center

Carvalho, Josue´; Queiroz, João A.; Cruz, Carla

2017-01-01

Circular dichroism (CD) has emerged as one of the standard biophysical techniques for the study of guaninequadruplex (G4) folding, cation effect, and ligand binding. The utility of this technique is based on its robustness, ease of use, and requirement of only small quantities of nucleic acid. This experiment is also extendable to the classroom…

Results of transcatheter pulmonary valvulation in native or patched right ventricular outflow tracts.

PubMed

Malekzadeh-Milani, Sophie; Ladouceur, Magalie; Cohen, Sarah; Iserin, Laurence; Boudjemline, Younes

2014-11-01

Although widely accepted worldwide, indications for percutaneous valve replacement are limited to treatment of dysfunction of prosthetic conduits inserted in the right ventricular outflow tract (RVOT). There has been little evaluation of the use of the Melody(®) valve for patched non-circular pulmonary pathways. To evaluate the outcomes of Melody valve insertion in patients with a patched non-circular RVOT. We analysed procedural and outcomes data from 34 patients who underwent Melody valve implantation for a non-circular RVOT. RVOT preparation was done in all patients, using different techniques (conventional, Russian doll and/or PA jailing). Melody valve insertion was performed concomitantly in most patients. All procedures were successful. Sixteen patients had complex additional procedures, including the jailing technique (n=5), the Russian doll technique (n=6) and multiple stent implantations (Russian jailing; n=5). The remaining patients were treated using the conventional technique with systematic prestenting. Three early complications occurred: one haemoptysis; one residual RVOT obstruction needing recatheterization 48 hours after percutaneous pulmonary valve implantation; and one stent embolization during advancement of the Ensemble(®) delivery system. The mean follow-up period was 2.6 years postprocedure. There was no stent fracture, migration or embolization. Two patients developed a significant paraprosthetic leak and one received a second Melody valve. Careful patient selection, balloon sizing and RVOT preparation with prestenting are required to create a safe landing zone for the Melody valve. Short-term follow-up shows excellent results with no stent fracture or migration and appears promising. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Photoexcitation circular dichroism in chiral molecules

NASA Astrophysics Data System (ADS)

Beaulieu, S.; Comby, A.; Descamps, D.; Fabre, B.; Garcia, G. A.; Géneaux, R.; Harvey, A. G.; Légaré, F.; Mašín, Z.; Nahon, L.; Ordonez, A. F.; Petit, S.; Pons, B.; Mairesse, Y.; Smirnova, O.; Blanchet, V.

2018-05-01

Chiral effects appear in a wide variety of natural phenomena and are of fundamental importance in science, from particle physics to metamaterials. The standard technique of chiral discrimination—photoabsorption circular dichroism—relies on the magnetic properties of a chiral medium and yields an extremely weak chiral response. Here, we propose and demonstrate an orders of magnitude more sensitive type of circular dichroism in neutral molecules: photoexcitation circular dichroism. This technique does not rely on weak magnetic effects, but takes advantage of the coherent helical motion of bound electrons excited by ultrashort circularly polarized light. It results in an ultrafast chiral response and the efficient excitation of a macroscopic chiral density in an initially isotropic ensemble of randomly oriented chiral molecules. We probe this excitation using linearly polarized laser pulses, without the aid of further chiral interactions. Our time-resolved study of vibronic chiral dynamics opens a way to the efficient initiation, control and monitoring of chiral chemical change in neutral molecules at the level of electrons.

Circular stapled pyloroplasty: a fast and effective technique for pyloric disruption during esophagectomy with gastric pull-up.

PubMed

Oezcelik, A; DeMeester, S R; Hindoyan, K; Leers, J M; Ayazi, S; Abate, E; Zehetner, J; Hagen, J A; Lipham, J C; DeMeester, T R

2011-08-01

The necessity of pyloroplasty after esophagectomy and gastric pull-up is debated. Disadvantages of a standard pyloroplasty include the potential for leak, shortening of the length of the graft, and complexity when done during a minimally invasive procedure. The aim of this study is to report our experience with a novel internal pyloroplasty technique using a circular stapler (CS pyloroplasty), which is applicable for both laparoscopic and open esophagectomy. The records of all patients who underwent an esophagectomy with gastric pull-up and pyloroplasty between 2002 and 2007 were reviewed. The CS pyloroplasty was performed through a lesser curve gastrotomy with a 21-mm CS, while the standard pyloroplasty entailed a longitudinal full thickness incision through the pylorus with mucosal closure in the same direction and a Graham patch. A CS pyloroplasty was performed in 144 and a standard pyloroplasty in 133 patients. The median patient age was 66years, and the median follow-up was 17months, and was similar for both types of pyloroplasty. Routine postoperative videoesophagram was significantly more likely to show a delay in contrast transit through the pylorus after standard pyloroplasty (16% standard vs. 8% CS pyloroplasty, P= 0.03). Significantly more patients had postoperative endoscopy after standard pyloroplasty (40% standard vs. 24% CS pyloroplasty, P= 0.004), but the frequency of pyloric dilatation was similar. There were no leaks with either technique. A circular stapled pyloroplasty is as efficacious as a standard pyloroplasty after esophagectomy with gastric pull-up. Potential advantages include the ease and simplicity of the procedure along with virtually no risk of a leak and no graft shortening. The technique is amenable to both open and minimally invasive procedures. © 2011 Copyright the Authors. Journal compilation © 2011, Wiley Periodicals, Inc. and the International Society for Diseases of the Esophagus.

A comparative study of corrugated horn design by evolutionary techniques

NASA Technical Reports Server (NTRS)

Hoorfar, A.

2003-01-01

Here an evolutionary programming algorithm is used to optimize the pattern of a corrugated circular horn subject to various constraints on return loss, antenna beamwidth, pattern circularity, and low cross polarization.

DOUBLE ENDOR with a linearly and a circularly polarized radiofrequency field

NASA Astrophysics Data System (ADS)

Schweiger, A.; Rudin, M.; Forrer, J.; Günthard, Hs. H.

The combination of the two spectroscopical techniques, DOUBLE ENDOR and ENDOR with a circularly polarized radiofrequency field (CP-ENDOR), is described. with this new method, termed by the acronym CP-DOUBLE ENDOR, the selective induction of transitions of different types of nuclei and of different paramagnetic species allows a drastic reduction of the number of observed ENDOR lines. With this technique, analysis of hitherto not interpretable ENDOR spectra is often made possible. The experimental setup of the CP-DOUBLE ENDOR spectrometer is described. The advantage of using circularly polarized rf fields in DOUBLE ENDOR spectroscopy is illustrated by two applications on transition metal complexes in single crystals.

Laparoscopic discoid anterior rectal excision with the circular stapler for rectosigmoid endometriosis, performed by the gynecologic surgeon.

PubMed

Zanatta, Alysson; Sousa, Jânio S; Machado, Ricardo L; Polcheira, Paulo A

2015-01-01

To demonstrate the technique of laparoscopic discoid anterior rectal wall resection using a circular stapler, feasible in the case of rectosigmoid endometriosis lesions measuring ≤ 3 cm. Case report (Canadian Task Force classification III). Private practice hospital in São Paulo, Brazil. Thirty-four-year-old woman with pelvic deep endometriosis including a 2-cm lesion in the rectosigmoid situated 11 cm proximally to the anal border. She had chronic pelvic pain, dysmenorrhea, dyspareunia, and constipation. She had undergone no previous surgical procedures. Standard 4-puncture laparoscopy was performed, and all visible endometriosis lesions were first removed before proceeding to rectal resection. The avascular rectovaginal space was identified, and the rectosigmoid was mobilized cranially, releasing the vagina and increasing the final distance of the bowel anastomosis to the anal border. The rectosigmoid nodule was isolated in its entire circumference and remained restricted to the anterior wall of the bowel. It was then transfixed using a 2-0 polyglycolic suture, with the healthy proximal and distal limits of the bowel included in the suture. A 33-cm endoscopic circular stapler was introduced via the anus up to the distal limit of the lesion and opened inside the bowel lumen. By pulling the edges of the suture, the rectosigmoid nodule was introduced inside of the circular stapler. It was fired to resect the anterior rectal wall, and the anastomosis was situated at the anterior and lateral walls of the bowel. Integrity of the bowel was checked via infusion of saline solution with methylene blue dye. Gynecologic surgeons performed all of the procedures. Bowel resection took 20 minutes, and the entire surgical procedure lasted 120 minutes. The patient was discharged after 48 hours. There were no intercurrent events, either early or late postoperatively. The patient was symptom-free at 2 years of follow-up. Laparoscopic discoid excision of an anterior rectal nodule using the circular stapler is an effective option for treating selected cases of rectosigmoid endometriosis. The technique might be reproducible by gynecologic surgeons after proper training. Copyright © 2015 AAGL. Published by Elsevier Inc. All rights reserved.

Synchrotron Radiation Circular Dichroism (SRCD) Spectroscopy - An Enhanced Method for Examining Protein Conformations and Protein Interactions

DOE Office of Scientific and Technical Information (OSTI.GOV)

B Wallace; R Janes

CD (circular dichroism) spectroscopy is a well-established technique in structural biology. SRCD (synchrotron radiation circular dichroism) spectroscopy extends the utility and applications of conventional CD spectroscopy (using laboratory-based instruments) because the high flux of a synchrotron enables collection of data at lower wavelengths (resulting in higher information content), detection of spectra with higher signal-to-noise levels and measurements in the presence of absorbing components (buffers, salts, lipids and detergents). SRCD spectroscopy can provide important static and dynamic structural information on proteins in solution, including secondary structures of intact proteins and their domains, protein stability, the differences between wild-type and mutant proteins,more » the identification of natively disordered regions in proteins, and the dynamic processes of protein folding and membrane insertion and the kinetics of enzyme reactions. It has also been used to effectively study protein interactions, including protein-protein complex formation involving either induced-fit or rigid-body mechanisms, and protein-lipid complexes. A new web-based bioinformatics resource, the Protein Circular Dichroism Data Bank (PCDDB), has been created which enables archiving, access and analyses of CD and SRCD spectra and supporting metadata, now making this information publicly available. To summarize, the developing method of SRCD spectroscopy has the potential for playing an important role in new types of studies of protein conformations and their complexes.« less

A circular median filter approach for resolving directional ambiguities in wind fields retrieved from spaceborne scatterometer data

NASA Technical Reports Server (NTRS)

Schultz, Howard

1990-01-01

The retrieval algorithm for spaceborne scatterometry proposed by Schultz (1985) is extended. A circular median filter (CMF) method is presented, which operates on wind directions independently of wind speed, removing any implicit wind speed dependence. A cell weighting scheme is included in the algorithm, permitting greater weights to be assigned to more reliable data. The mathematical properties of the ambiguous solutions to the wind retrieval problem are reviewed. The CMF algorithm is tested on twelve simulated data sets. The effects of spatially correlated likelihood assignment errors on the performance of the CMF algorithm are examined. Also, consideration is given to a wind field smoothing technique that uses a CMF.

Catheter-based high-frequency intraluminal ultrasound imaging is a powerful tool to study esophageal dysmotility patients.

PubMed

Santander, Cecilio; Perea, Elena; Caldas, María; Clave, Pere

2017-05-01

High-resolution manometry (HRM) is currently the most important diagnostic test for esophageal motility disorders, providing information on the contraction pattern of the circular muscle layer, which helps classify these esophageal motor diseases. However, with the increasing development of ultrasound, other techniques, such as high-frequency intraluminal ultrasound (HFIUS), have gained importance. This technique uses a flexible shaft with a central wire integrated into a standard endoscope, which facilitates real-time sonography. Its main utility is to provide anatomical information on the structure of the esophageal wall, including both the circular and longitudinal layers that constitute the esophageal muscularis propria. Increasing knowledge about these motility disorders has led to the hypothesis that, in addition to an abnormal contraction pattern of the circular muscle, an overall increased muscle thickness and an abnormal longitudinal muscle contraction could be added as pathophysiological factors. The increase in muscle thickness could be an important indicator of the severity of diseases, such as achalasia, distal esophageal spasm, or hypercontractile esophagus. More studies are required before definitive conclusions can be reached, but HFIUS employed simultaneously with HRM could provide a more complete and precise evaluation of these esophageal motor disorders. © 2017 New York Academy of Sciences.

Outlier detection in a new half-circular distribution

NASA Astrophysics Data System (ADS)

Rambli, Adzhar; Mohamed, Ibrahim Bin; Shimizu, Kunio; Khalidin, Nurliza

2015-10-01

In this paper, we use a discordancy test based on spacing theory to detect outlier in a half-circular data. Up to now, numerous discordancy tests have been proposed to detect outlier in circular distributions which are defined in [0,2π). However, some circular data lie within just half of this range. Therefore, first we introduce a new half-circular distribution developed using the inverse stereographic projection technique on a gamma distributed variable. Then, we develop a new discordancy test to detect single or multiple outliers in the half-circular data based on the spacing theory. We show the practical value of the test by applying it to an eye data set obtained from a glaucoma clinic at the University of Malaya Medical Centre, Malaysia.

A novel one-shot circular stapler closure for atrial septal defect in a beating-heart porcine model.

PubMed

Tarui, Tatsuya; Tomita, Shigeyuki; Ishikawa, Norihiko; Ohtake, Hiroshi; Watanabe, Go

2015-02-01

In surgical atrial septal defect (ASD) closure, there are no techniques or devices that can close the ASD accurately in a short time under a beating heart. We have developed a simple and automatic ASD closure technique using a circular stapler. This study assessed the feasibility and efficacy of a new circular stapler closure for ASD. Under a continuous beating heart, hand-sewn patch plasty ASD closure was performed in 6 pigs (group A) and circular stapler ASD closure was performed in 6 pigs (group B). The time to close the ASD and the effectiveness of the closure were compared. Closure was significantly faster in group B (10.5 ± 1.0 seconds) than in group A (664 ± 10 seconds; p < 0.05). There was no leakage at the closure site, and sufficient tolerance was confirmed. A circular stapler can be used to treat ASD faster than hand-sewn patch plasty, with sufficient pressure tolerance in a beating heart porcine model. Copyright © 2015 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

A noncontact laser technique for circular contouring accuracy measurement

NASA Astrophysics Data System (ADS)

Wang, Charles; Griffin, Bob

2001-02-01

The worldwide competition in manufacturing frequently requires the high-speed machine tools to deliver contouring accuracy in the order of a few micrometers, while moving at relatively high feed rates. Traditional test equipment is rather limited in its capability to measure contours of small radius at high speed. Described here is a new noncontact laser measurement technique for the test of circular contouring accuracy. This technique is based on a single-aperture laser Doppler displacement meter with a flat mirror as the target. It is of a noncontact type with the ability to vary the circular path radius continuously at data rates of up to 1000 Hz. Using this instrument, the actual radius, feed rate, velocity, and acceleration profiles can also be determined. The basic theory of operation, the hardware setup, the data collection, the data processing, and the error budget are discussed.

PCDDB: new developments at the Protein Circular Dichroism Data Bank.

PubMed

Whitmore, Lee; Miles, Andrew John; Mavridis, Lazaros; Janes, Robert W; Wallace, B A

2017-01-04

The Protein Circular Dichroism Data Bank (PCDDB) has been in operation for more than 5 years as a public repository for archiving circular dichroism spectroscopic data and associated bioinformatics and experimental metadata. Since its inception, many improvements and new developments have been made in data display, searching algorithms, data formats, data content, auxillary information, and validation techniques, as well as, of course, an increase in the number of holdings. It provides a site (http://pcddb.cryst.bbk.ac.uk) for authors to deposit experimental data as well as detailed information on methods and calculations associated with published work. It also includes links for each entry to bioinformatics databases. The data are freely available to accessors either as single files or as complete data bank downloads. The PCDDB has found broad usage by the structural biology, bioinformatics, analytical and pharmaceutical communities, and has formed the basis for new software and methods developments. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

Stapled haemorrhoidopexy: a consensus position paper by an international working party - indications, contra-indications and technique.

PubMed

Corman, M L; Gravié, J-F; Hager, T; Loudon, M A; Mascagni, D; Nyström, P-O; Seow-Choen, F; Abcarian, H; Marcello, P; Weiss, E; Longo, A

2003-07-01

An international working party with experience in the performance of an alternative haemorrhoid operation through the use of the circular stapler was convened for the purpose of developing a consensus as to the criteria for undertaking this procedure. The agenda consisted of first, naming the operation; second, the indications and contra-indications for its performance; and third, the preferred surgical technique. Among the recommendations for individuals who plan to embark on this surgery are that experience with anorectal surgery and an understanding of anorectal anatomy are requisites; experience with circular stapling devices is essential; and the surgeon must attend a formal course which should include lectures, videos, the application of the instrument in models, and observation of the operation as performed by a surgeon recognized by his or her peers-leading ultimately to undertaking the procedure while being observed by an experienced surgeon. Following satisfactory completion of the above, independent responsibility should be determined by an individual's department of surgery.

Laparoscopic and thoracoscopic esophagectomy with intrathoracic anastomosis for middle or lower esophageal carcinoma

PubMed Central

Ai, Bo; Zhang, Zheng

2014-01-01

Thoracoscopic mobilization of esophagus and laparoscopic mobilization of stomach with cervical anastomosis is employed widely in minimally invasive esophagectomy (MIE) for esophageal carcinoma. However, it is associated with high incidence of complications, including recurrent laryngeal nerve injury and anastomotic leak. This paper summarizes the key techniques in total laparoscopic and thoracoscopic esophagectomy with intrathoracic anastomosis for MIE in 62 patients of middle or lower esophageal cancer between March 2012 and August 2013. Total laparoscopic and thoracoscopic esophagectomy with intrathoracic anastomosis was performed to treat the middle or lower esophageal cancer. Laparoscopic and thoracoscopic Ivor-Lewis esophagectomy was performed using a circular stapler (Johnson and Johnson) intrathoracically to staple esophagogastric anastomosis and reconstruct the digestive tract. In addition, we performed tension-relieving anastomotic suture and embedded with pedicled omental flap. Compared with the trans-orally inserted anvil (OrVil) approach, the technique reported here is safe, feasible and user-friendly. Total thoracoscopic intrathoracic anastomosis can be performed with a circular stapler (Johnson and Johnson). PMID:25276383

Laparoscopic and thoracoscopic esophagectomy with intrathoracic anastomosis for middle or lower esophageal carcinoma.

PubMed

Ai, Bo; Zhang, Zheng; Liao, Yongde

2014-09-01

Thoracoscopic mobilization of esophagus and laparoscopic mobilization of stomach with cervical anastomosis is employed widely in minimally invasive esophagectomy (MIE) for esophageal carcinoma. However, it is associated with high incidence of complications, including recurrent laryngeal nerve injury and anastomotic leak. This paper summarizes the key techniques in total laparoscopic and thoracoscopic esophagectomy with intrathoracic anastomosis for MIE in 62 patients of middle or lower esophageal cancer between March 2012 and August 2013. Total laparoscopic and thoracoscopic esophagectomy with intrathoracic anastomosis was performed to treat the middle or lower esophageal cancer. Laparoscopic and thoracoscopic Ivor-Lewis esophagectomy was performed using a circular stapler (Johnson and Johnson) intrathoracically to staple esophagogastric anastomosis and reconstruct the digestive tract. In addition, we performed tension-relieving anastomotic suture and embedded with pedicled omental flap. Compared with the trans-orally inserted anvil (OrVil) approach, the technique reported here is safe, feasible and user-friendly. Total thoracoscopic intrathoracic anastomosis can be performed with a circular stapler (Johnson and Johnson).

Tomographic reconstruction of circularly polarized high-harmonic fields: 3D attosecond metrology

PubMed Central

Chen, Cong; Tao, Zhensheng; Hernández-García, Carlos; Matyba, Piotr; Carr, Adra; Knut, Ronny; Kfir, Ofer; Zusin, Dimitry; Gentry, Christian; Grychtol, Patrik; Cohen, Oren; Plaja, Luis; Becker, Andreas; Jaron-Becker, Agnieszka; Kapteyn, Henry; Murnane, Margaret

2016-01-01

Bright, circularly polarized, extreme ultraviolet (EUV) and soft x-ray high-harmonic beams can now be produced using counter-rotating circularly polarized driving laser fields. Although the resulting circularly polarized harmonics consist of relatively simple pairs of peaks in the spectral domain, in the time domain, the field is predicted to emerge as a complex series of rotating linearly polarized bursts, varying rapidly in amplitude, frequency, and polarization. We extend attosecond metrology techniques to circularly polarized light by simultaneously irradiating a copper surface with circularly polarized high-harmonic and linearly polarized infrared laser fields. The resulting temporal modulation of the photoelectron spectra carries essential phase information about the EUV field. Utilizing the polarization selectivity of the solid surface and by rotating the circularly polarized EUV field in space, we fully retrieve the amplitude and phase of the circularly polarized harmonics, allowing us to reconstruct one of the most complex coherent light fields produced to date. PMID:26989782

Astronomy in Denver: Probing Interstellar Circular Polarization with Polvis, a Full Stokes Single Shot Polarimeter

NASA Astrophysics Data System (ADS)

Wolfe, Tristan; Stencel, Robert E.

2018-06-01

Measurements of optical circular polarization (Stokes V) introduced by dust grains in the ISM are important for two main reasons. First of all, the polarization itself contains information about the metallic versus dielectric composition of the dust grains themselves (H. C. van de Hulst 1957, textbook). Additionally, circular polarization can help constrain the interstellar component of the polarization of any source that may have intrinsic polarization, which needs to be calibrated for astrophysical study. Though interstellar circular polarization has been observed (P. G. Martin 1972, MNRAS 159), most broadband measurements of ISM polarization include linear polarization only (Stokes Q and U), due to the relatively low circular polarization signal and the added instrumentation complexity of including V-measurement capability. Prior circular polarization measurements have also received very little follow-up in the past several decades, even as polarimeters have become more accurate due to advances in technology. The University of Denver is pursuing these studies with POLVIS, a prototype polarimeter that utilizes a stress-engineered optic ("SEO", A. K. Spilman and T. G. Brown 2007, Applied Optics IP 46) to produce polarization-dependent PSFs (A. M. Beckley and T. G. Brown 2010, Proc SPIE 7570). These PSFs are analyzed to provide simultaneous Stokes I, Q, U, and V measurements, in a single beam and single image, along the line-of-sight to point source-like objects. Polvis is the first polarimeter to apply these optics and measurement techniques for astronomical observations. We present the first results of this instrument in B, V, and R wavebands, providing a fresh look at full Stokes interstellar polarization. Importantly, this set of efforts will constrain the ISM contribution to the polarization with respect to intrinsic stellar components. The authors are grateful to the estate of William Herschel Womble for the support of astronomy at the University of Denver, and for funding provided by the Mt. Cuba Astronomical Foundation.

A new method to measure circular runout of end-milling spindle based on cutting mark

NASA Astrophysics Data System (ADS)

Zhou, Jianlai; Liu, Shuchun

2008-12-01

A practical method is introduced to measure the circular runout of a end-milling spindle system at high speed rotations without the need of a reference sphere. A workpiece is held on a linear slide which moves along the axial direction of the spindle. The spindle is then programmed to run at a specific speed. A very sharp edge cutter must be used and the depth of cut will be very shallow in order to keep the cutting force very small. The workpiece is then fed into the end mill in order to make a cutting mark of teens μm in depth. The cutting marks are circular, and their diameters are related to the circular runout of the spindle system. The cutting mark that is generated at a specific speed is expected to contain information about the spindle circular runout at this speed. In practice the cutting marks are not perfectly circular. Therefore, a best-fit circle of a cutting mark is needed to determine its diameter. A high-resolution edge detector machine is used for this purpose. Quantitative precision analysis was carried out to confirm the accuracy and repeatability of this new measurement technique. It is demonstrated that this technique for the measurement of spindle circular runout is an effective tool in verifying the actual running accuracy of spindles at their actual operating speeds and can be accomplished without the need for a reference sphere.

Thermal Imaging of Flame in Air-assisted Atomizer for Burner System

NASA Astrophysics Data System (ADS)

Amirnordin, S. H.; Khalid, Amir; Zailan, M. F.; Fawzi, Mas; Salleh, Hamidon; Zaman, Izzuddin

2017-08-01

Infrared thermography was used as a part of non-intrusion technique on the flame temperature analysis. This paper demonstrates the technique to generate the thermal images of flame from the air-assisted atomizer. The multi-circular jet plate acts as a turbulence generator to improve the fuel and air mixing in the atomizer. Three types of multi-circular jet plate geometry were analysed at different equivalence ratio. Thermal infrared imaging using FLIR thermal camera were used to obtain the flame temperature. Multi-circular jet 1 shows the highest flame temperature obtained compared to other plates. It can be concluded that the geometry of the plate influences the combustion, hence affects the flame temperature profile from the air-assisted atomizer.

Feasibility of automated dropsize distributions from holographic data using digital image processing techniques. [particle diameter measurement technique

NASA Technical Reports Server (NTRS)

Feinstein, S. P.; Girard, M. A.

1979-01-01

An automated technique for measuring particle diameters and their spatial coordinates from holographic reconstructions is being developed. Preliminary tests on actual cold-flow holograms of impinging jets indicate that a suitable discriminant algorithm consists of a Fourier-Gaussian noise filter and a contour thresholding technique. This process identifies circular as well as noncircular objects. The desired objects (in this case, circular or possibly ellipsoidal) are then selected automatically from the above set and stored with their parametric representations. From this data, dropsize distributions as a function of spatial coordinates can be generated and combustion effects due to hardware and/or physical variables studied.

Is cepstrum averaging applicable to circularly polarized electric-field data?

NASA Astrophysics Data System (ADS)

Tunnell, T.

1990-04-01

In FY 1988 a cepstrum averaging technique was developed to eliminate the ground reflections from charged particle beam (CPB) electromagnetic pulse (EMP) data. The work was done for the Los Alamos National Laboratory Project DEWPOINT at SST-7. The technique averages the cepstra of horizontally and vertically polarized electric field data (i.e., linearly polarized electric field data). This cepstrum averaging technique was programmed into the FORTRAN codes CEP and CEPSIM. Steve Knox, the principal investigator for Project DEWPOINT, asked the authors to determine if the cepstrum averaging technique could be applied to circularly polarized electric field data. The answer is, Yes, but some modifications may be necessary. There are two aspects to this answer that we need to address, namely, the Yes and the modifications. First, regarding the Yes, the technique is applicable to elliptically polarized electric field data in general: circular polarization is a special case of elliptical polarization. Secondly, regarding the modifications, greater care may be required in computing the phase in the calculation of the complex logarithm. The calculation of the complex logarithm is the most critical step in cepstrum-based analysis. This memorandum documents these findings.

An equivalent network representation of a clamped bimorph piezoelectric micromachined ultrasonic transducer with circular and annular electrodes using matrix manipulation techniques.

PubMed

Sammoura, Firas; Smyth, Katherine; Kim, Sang-Gook

2013-09-01

An electric circuit model for a clamped circular bimorph piezoelectric micromachined ultrasonic transducer (pMUT) was developed for the first time. The pMUT consisted of two piezoelectric layers sandwiched between three thin electrodes. The top and bottom electrodes were separated into central and annular electrodes by a small gap. While the middle electrode was grounded, the central and annular electrodes were biased with two independent voltage sources. The strain mismatch between the piezoelectric layers caused the plate to vibrate and transmit a pressure wave, whereas the received echo generated electric charges resulting from plate deformation. The clamped pMUT plate was separated into a circular and an annular plate, and the respective electromechanical transformation matrices were derived. The force and velocity vectors were properly selected using Hamilton's principle and the necessary boundary conditions were invoked. The electromechanical transformation matrix for the clamped circular pMUT was deduced using simple matrix manipulation techniques. The pMUT performance under three biasing schemes was elaborated: 1) central electrode only, 2) central and annular electrodes with voltages of the same magnitude and polarity, and 3) central and annular electrodes with voltages of the same magnitude and opposite polarity. The circuit parameters of the pMUT were extracted for each biasing scheme, including the transformer ratio, the clamped electric impedance, and the open-circuit mechanical impedance. Each pMUT scheme was characterized under different acoustic loadings using the theoretically developed model, which was verified with finite element modeling (FEM) simulation. The electrode size was optimized to maximize the electromechanical transformer ratio. As such, the developed model could provide more insight into the design, optimization, and characterization of pMUTs and allow for performance comparison with their cMUT counterparts.

Prospective experimental study of transrectal viscerotomy closure using transanal endoscopic suture vs. circular stapler: a step toward NOTES.

PubMed

Diana, M; Leroy, J; Wall, J; De Ruijter, V; Lindner, V; Dhumane, P; Mutter, D; Marescaux, J

2012-06-01

Endoluminal full-thickness closure of the rectal wall is critical in emerging procedures including endoscopic submucosal dissection and transrectal natural orifice transluminal endoscopic surgery (NOTES). This study aimed to compare manual suture using the transanal endoscopic operation platform (TEO; Karl Storz, Tüttlingen, Germany) with the end-to-end anastomosis hemorrhoid circular stapler (EEA; Covidien, Dublin, Ireland) for closure of the rectal viscerotomy during transrectal NOTES segmental colectomy. A total of 12 swine underwent transrectal hybrid NOTES partial colectomies. Animals were divided into two groups according to the viscerotomy closure technique: 1) TEO manual suture; 2) EEA circular stapler closure. Mean (± SD) viscerotomy closure time was 67.5 ± 59.5 minutes and 31.5 ± 19.6 minutes for TEO and EEA, respectively. There was one conversion to laparoscopy in the TEO group and a misfiring in the EEA group that required a TEO salvage suture. There was one positive air-leak test in each group. Peritoneal fluid collected at the end of the procedure tested positive for bacterial contamination in all cases. A mild stenosis was present in 4 /6 viscerotomies (67 %) in the TEO group and in 1/6 (17 %) in the EEA group on endoscopic control. Inflammatory changes were mild in 3/5 (60 %) and 4/5 (80 %) viscerotomies in the TEO and EEA groups, respectively, whereas severe inflammation was found in 2/5 (TEO) and 1 /5 (EEA). Transrectal viscerotomy closure using the EEA circular stapler technique is feasible, easy to perform, and histologically comparable to suture closure through a TEO platform. It may offer an attractive alternative for NOTES segmental colectomies and endoscopic resections. © Georg Thieme Verlag KG Stuttgart · New York.

High Contrast Internal and External Coronagraph Masks Produced by Various Techniques

NASA Technical Reports Server (NTRS)

Balasubramanian, Kunjithapatha; Wilson, Daniel; White, Victor; Muller, Richard; Dickie, Matthew; Yee, Karl; Ruiz, Ronald; Shaklan, Stuart; Cady, Eric; Kern, Brian;

Helicity-Selective Enhancement and Polarization Control of Attosecond High Harmonic Waveforms Driven by Bichromatic Circularly Polarized Laser Fields.

PubMed

Dorney, Kevin M; Ellis, Jennifer L; Hernández-García, Carlos; Hickstein, Daniel D; Mancuso, Christopher A; Brooks, Nathan; Fan, Tingting; Fan, Guangyu; Zusin, Dmitriy; Gentry, Christian; Grychtol, Patrik; Kapteyn, Henry C; Murnane, Margaret M

2017-08-11

High harmonics driven by two-color counterrotating circularly polarized laser fields are a unique source of bright, circularly polarized, extreme ultraviolet, and soft x-ray beams, where the individual harmonics themselves are completely circularly polarized. Here, we demonstrate the ability to preferentially select either the right or left circularly polarized harmonics simply by adjusting the relative intensity ratio of the bichromatic circularly polarized driving laser field. In the frequency domain, this significantly enhances the harmonic orders that rotate in the same direction as the higher-intensity driving laser. In the time domain, this helicity-dependent enhancement corresponds to control over the polarization of the resulting attosecond waveforms. This helicity control enables the generation of circularly polarized high harmonics with a user-defined polarization of the underlying attosecond bursts. In the future, this technique should allow for the production of bright highly elliptical harmonic supercontinua as well as the generation of isolated elliptically polarized attosecond pulses.

The effect of different distance measures in detecting outliers using clustering-based algorithm for circular regression model

NASA Astrophysics Data System (ADS)

Di, Nur Faraidah Muhammad; Satari, Siti Zanariah

2017-05-01

Outlier detection in linear data sets has been done vigorously but only a small amount of work has been done for outlier detection in circular data. In this study, we proposed multiple outliers detection in circular regression models based on the clustering algorithm. Clustering technique basically utilizes distance measure to define distance between various data points. Here, we introduce the similarity distance based on Euclidean distance for circular model and obtain a cluster tree using the single linkage clustering algorithm. Then, a stopping rule for the cluster tree based on the mean direction and circular standard deviation of the tree height is proposed. We classify the cluster group that exceeds the stopping rule as potential outlier. Our aim is to demonstrate the effectiveness of proposed algorithms with the similarity distances in detecting the outliers. It is found that the proposed methods are performed well and applicable for circular regression model.

Transcriptome-wide discovery of circular RNAs in Archaea

PubMed Central

Danan, Miri; Schwartz, Schraga; Edelheit, Sarit; Sorek, Rotem

2012-01-01

Circular RNA forms had been described in all domains of life. Such RNAs were shown to have diverse biological functions, including roles in the life cycle of viral and viroid genomes, and in maturation of permuted tRNA genes. Despite their potentially important biological roles, discovery of circular RNAs has so far been mostly serendipitous. We have developed circRNA-seq, a combined experimental/computational approach that enriches for circular RNAs and allows profiling their prevalence in a whole-genome, unbiased manner. Application of this approach to the archaeon Sulfolobus solfataricus P2 revealed multiple circular transcripts, a subset of which was further validated independently. The identified circular RNAs included expected forms, such as excised tRNA introns and rRNA processing intermediates, but were also enriched with non-coding RNAs, including C/D box RNAs and RNase P, as well as circular RNAs of unknown function. Many of the identified circles were conserved in Sulfolobus acidocaldarius, further supporting their functional significance. Our results suggest that circular RNAs, and particularly circular non-coding RNAs, are more prevalent in archaea than previously recognized, and might have yet unidentified biological roles. Our study establishes a specific and sensitive approach for identification of circular RNAs using RNA-seq, and can readily be applied to other organisms. PMID:22140119

The velocity and vorticity fields of the turbulent near wake of a circular cylinder

NASA Technical Reports Server (NTRS)

Wallace, James; Ong, Lawrence; Moin, Parviz

1995-01-01

The purpose of this research is to provide a detailed experimental database of velocity and vorticity statistics in the very near wake (x/d less than 10) of a circular cylinder at Reynolds number of 3900. This study has determined that estimations of the streamwise velocity component in flow fields with large nonzero cross-stream components are not accurate. Similarly, X-wire measurements of the u and v velocity components in flows containing large w are also subject to the errors due to binormal cooling. Using the look-up table (LUT) technique, and by calibrating the X-wire probe used here to include the range of expected angles of attack (+/- 40 deg), accurate X-wire measurements of instantaneous u and v velocity components in the very near wake region of a circular cylinder has been accomplished. The approximate two-dimensionality of the present flow field was verified with four-wire probe measurements, and to some extent the spanwise correlation measurements with the multisensor rake. Hence, binormal cooling errors in the present X-wire measurements are small.

Direct Position Determination of Multiple Non-Circular Sources with a Moving Coprime Array.

PubMed

Zhang, Yankui; Ba, Bin; Wang, Daming; Geng, Wei; Xu, Haiyun

2018-05-08

Direct position determination (DPD) is currently a hot topic in wireless localization research as it is more accurate than traditional two-step positioning. However, current DPD algorithms are all based on uniform arrays, which have an insufficient degree of freedom and limited estimation accuracy. To improve the DPD accuracy, this paper introduces a coprime array to the position model of multiple non-circular sources with a moving array. To maximize the advantages of this coprime array, we reconstruct the covariance matrix by vectorization, apply a spatial smoothing technique, and converge the subspace data from each measuring position to establish the cost function. Finally, we obtain the position coordinates of the multiple non-circular sources. The complexity of the proposed method is computed and compared with that of other methods, and the Cramer⁻Rao lower bound of DPD for multiple sources with a moving coprime array, is derived. Theoretical analysis and simulation results show that the proposed algorithm is not only applicable to circular sources, but can also improve the positioning accuracy of non-circular sources. Compared with existing two-step positioning algorithms and DPD algorithms based on uniform linear arrays, the proposed technique offers a significant improvement in positioning accuracy with a slight increase in complexity.

A modal separation measurement technique for broadband noise propagating inside circular ducts

NASA Technical Reports Server (NTRS)

Kerschen, E. J.; Johnston, J. P.

1981-01-01

A measurement technique which separates broadband noise propagating inside circular ducts into the acoustic duct modes is developed. The technique is also applicable to discrete frequency noise. The acoustic modes are produced by weighted combinations of the instantaneous outputs of microphones spaced around the duct circumference. The technique is compared with the cross spectral density approach presently available and found to have certain advantages, and disadvantages. Considerable simplification of both the new technique and the cross spectral density approach occurs when no correlation exists between different circumferential mode orders. The properties leading to uncorrelated modes and experimental tests which verify this condition are discussed. The modal measurement technique is applied to the case of broadband noise generated by flow through a coaxial obstruction (nozzle or orifice) in a pipe. Different circumferential mode orders are shown to be uncorrelated for this type of noise source.

Horizontal square buried sutures in a two-layered fashion enable direct primary closure for small circular wounds without dog-ears on the face.

PubMed

Matsunaga, Jun; Aiba, Setsuya

2005-05-01

Dog-ears often lead to lengthening of an excision, and it is desirable to avoid them. Facial skin, including the subepidermal connective tissue, is flexible and can be used advantageously to minimize dog-ears using a novel buried suture technique. After removing a round lesion, the first horizontal square buried suture (HSBS) was deeply placed parallel to the longitudinal direction of the defect beneath superficial fascia. After the first HSBS was tied, the defect became fusiform but was still largely open. The second HSBS was also placed parallel to the longitudinal direction of the defect but in more superficial fascia and using smaller horizontal buried loops than those of the first deep suture. After the second HSBS in the middle of the dermis was tied, the wound was almost closed without dog-ears. Consequently, few skin sutures were required to finish the operation. Using this technique, a small circular or oval defect on the face up to 1 cm in diameter can be closed without any additional excision of the skin and without creating dog-ears.

Hinged Capsulotomy – Does it Decrease Floaters After Yttrium Aluminum Garnet Laser Capsulotomy?

PubMed Central

Alipour, Fatemeh; Jabbarvand, Mahmoud; Hashemian, Hesam; Hosseini, Simindokht; Khodaparast, Mehdi

2015-01-01

Objectives: The objective was to compare conventional circular yttrium aluminum garnet (YAG) laser capsulotomy with hinged capsulotomy to manage posterior capsular opacification (PCO). Materials and Methods: This prospective, randomized clinical trial enrolled pseudophakic patients with visually significant posterior capsule opacification. Patients were randomized to undergo posterior YAG laser capsulotomy with either conventional circular technique or a new technique with an inferior hinge. At 1-month postoperatively, patients were asked if they had any annoying floaters and the responses were compared between groups. P < 0.05 was considered statistically significant. Results: A total of 83 patients were enrolled. Forty-three patients underwent hinged posterior YAG capsulotomy and 40 patients underwent routine circular capsulotomy. At 1-month postoperatively, there was a statistically significant decrease in annoying floaters in the group that underwent circular capsulotomy (P = 0.02). There was no statistically significant association in the total energy delivered (P = 0.4) or the number of spots (P = 0.2) and patient perception of annoying floaters. Conclusion: Hinged YAG capsulotomy was effective at decreasing the rate of floaters in patients with PCO. PMID:26180476

Hinged Capsulotomy--Does it Decrease Floaters After Yttrium Aluminum Garnet Laser Capsulotomy?

PubMed

Alipour, Fatemeh; Jabbarvand, Mahmoud; Hashemian, Hesam; Hosseini, Simindokht; Khodaparast, Mehdi

2015-01-01

The objective was to compare conventional circular yttrium aluminum garnet (YAG) laser capsulotomy with hinged capsulotomy to manage posterior capsular opacification (PCO). This prospective, randomized clinical trial enrolled pseudophakic patients with visually significant posterior capsule opacification. Patients were randomized to undergo posterior YAG laser capsulotomy with either conventional circular technique or a new technique with an inferior hinge. At 1-month postoperatively, patients were asked if they had any annoying floaters and the responses were compared between groups. P < 0.05 was considered statistically significant. A total of 83 patients were enrolled. Forty-three patients underwent hinged posterior YAG capsulotomy and 40 patients underwent routine circular capsulotomy. At 1-month postoperatively, there was a statistically significant decrease in annoying floaters in the group that underwent circular capsulotomy (P = 0.02). There was no statistically significant association in the total energy delivered (P = 0.4) or the number of spots (P = 0.2) and patient perception of annoying floaters. Hinged YAG capsulotomy was effective at decreasing the rate of floaters in patients with PCO.

Probing ultrafast spin dynamics with high-harmonic magnetic circular dichroism spectroscopy

NASA Astrophysics Data System (ADS)

Willems, F.; Smeenk, C. T. L.; Zhavoronkov, N.; Kornilov, O.; Radu, I.; Schmidbauer, M.; Hanke, M.; von Korff Schmising, C.; Vrakking, M. J. J.; Eisebitt, S.

2015-12-01

Magnetic circular dichroism in the extreme ultraviolet (XUV) spectral range is a powerful technique for element-specific probing of magnetization in multicomponent magnetic alloys and multilayers. We combine a high-harmonic generation source with a λ /4 phase shifter to obtain circularly polarized XUV femtosecond pulses for ultrafast magnetization studies. We report on simultaneously measured resonant magnetic circular dichroism (MCD) of Co and Ni at their respective M2 ,3 edges and of Pt at its O edge, originating from interface magnetism. We present a time-resolved MCD absorption measurement of a thin magnetic Pt/Co/Pt film, showing simultaneous demagnetization of Co and Pt on a femtosecond time scale.

Circular External Fixation as a Primary or Adjunctive Therapy for the Podoplastic Approach of the Diabetic Charcot Foot.

PubMed

Short, Daniel J; Zgonis, Thomas

2017-01-01

Numerous techniques have been described for surgical management of the diabetic Charcot foot. External fixation has become a main surgical tool for the reconstructive foot and ankle surgeon when dealing with the ulcerated diabetic Charcot foot. In the presence of an open wound and/or osteomyelitis, staged reconstruction with circular external fixation becomes ideal for salvage of the diabetic lower extremity. Also, circular external fixation can provide simultaneous compression and stabilization, correct the underlying osseous or soft tissue deformities, and surgically offload the diabetic Charcot foot. This article describes a variety of circular external fixation applications for the diabetic Charcot foot. Copyright © 2016 Elsevier Inc. All rights reserved.

Calculation of stability derivatives for slowly oscillating bodies of revolution at Mach 1.0

NASA Technical Reports Server (NTRS)

Ruo, S. Y.; Liu, D. D.

1971-01-01

A parabolic method for steady transonic flow is extended to bodies of revolution oscillating in a sonic flow field. A Laplace transform technique is employed to derive the dipole solution, and the Adams-Sears iterative technique is used in the stability derivative calculation. A computer program is developed to perform the stability derivative calculation for the slowly oscillating cone and parabolic ogive. Inputs for the program are body geometry thickness ratio, acceleration constant, and pitch axis location. Sample calculations were performed for the parabolic ogive and circular cone and results are compared with those obtained by using other techniques and the available experimental data for circular cones.

Supermarkets and unhealthy food marketing: An international comparison of the content of supermarket catalogues/circulars.

PubMed

Charlton, Emma L; Kähkönen, Laila A; Sacks, Gary; Cameron, Adrian J

2015-12-01

Supermarket marketing activities have a major influence on consumer food purchases. This study aimed to assess and compare the contents of supermarket marketing circulars from a range of countries worldwide from an obesity prevention perspective. The contents of supermarket circulars from major supermarket chains in 12 non-random countries were collected and analysed over an eight week period from July to September 2014 (n=89 circulars with 12,563 food products). Circulars were largely English language and from countries representing most continents. Food products in 25 sub-categories were categorised as discretionary or non-discretionary (core) food or drinks based on the Australian Guide to Healthy Eating. The total number of products in each subcategory in the whole circular, and on front covers only, was calculated. Circulars from most countries advertised a high proportion of discretionary foods. The only exceptions were circulars from the Philippines (no discretionary foods) and India (11% discretionary food). Circulars from six countries advertised more discretionary foods than core foods. Front covers tended to include a much greater proportion of healthy products than the circulars overall. Supermarket circulars in most of the countries examined include a high percentage of discretionary foods, and therefore promote unhealthy eating behaviours that contribute to the global obesity epidemic. A clear opportunity exists for supermarket circulars to promote rather than undermine healthy eating behaviours of populations. Governments need to ensure that supermarket marketing is included as part of broader efforts to restrict unhealthy food marketing. Copyright © 2015 Elsevier Inc. All rights reserved.

A Wideband Circularly Polarized Antenna with a Multiple-Circular-Sector Dielectric Resonator.

PubMed

Trinh-Van, Son; Yang, Youngoo; Lee, Kang-Yoon; Hwang, Keum Cheol

2016-11-03

This paper presents the design of a wideband circularly polarized antenna using a multiple-circular-sector dielectric resonator (DR). The DR is composed of twelve circular-sector DRs with identical central angles of 30 ∘ but with different radii. A genetic algorithm is utilized to optimize the radii of the twelve circular-sector DRs to realize wideband circular polarization. The proposed antenna is excited using an aperture-coupled feeding technique through a narrow rectangular slot etched onto the ground plane. An antenna prototype is experimentally verified. The measured -10 dB reflection and 3 dB axial ratio (AR) bandwidths are 31.39% (1.88-2.58 GHz) and 19.30% (2.06-2.50 GHz), respectively, covering the operating bands of the following systems: UMTS-2100 (2.145 GHz), WiMAX (2.3 GHz), and Wi-Fi (2.445 GHz). A measured peak gain of 7.65 dBic at 2.225 GHz and gain variation of less than 2.70 dBic within the measured 3 dB AR bandwidth are achieved. In addition, the radiation patterns of the proposed antenna are presented and discussed.

Chirality sensing of bioactive compounds with amino alcohol unit via circular dichroism.

PubMed

Górecki, Marcin; Groszek, Grażyna; Frelek, Jadwiga

2017-10-01

The aim of the present work was to test various chiroptical techniques, including in particular the in situ dirhodium methodology, to assign the absolute configuration of 1,2- and 1,3-amino alcohols. As models, we selected mainly compounds that have both an additional strongly absorbing and interfering chromophoric system and application in medicinal chemistry. Determination of the absolute configuration (AC) of the tested molecules such as cinchona alkaloids, Tamiflu, and others was carried out using a combination of electronic and vibrational circular dichroism (ECD, VCD) spectroscopy. It has been demonstrated that both 1,2- and 1,3-aminol moieties are subject to the same sector rule correlating stereostructure of formed Rh 2 -complex with chiroptical properties, and that the changes in the position of the stereogenic center do not affect its proper use. © 2017 Wiley Periodicals, Inc.

Stricture Rate after Laparoscopic Roux-en-Y Gastric Bypass with a 21-mm Circular Stapler versus a 25-mm Linear Stapler

PubMed Central

Vunnamadala, Kalyan; Sakharpe, Aniket; Wilhelm, B. Jakub; Aksade, Artun

2015-01-01

Background: Obesity is estimated to affect more than one and a half billion adults. Laparoscopic Roux-en-Y gastric bypass (LRYGB) has become one of the preferred weight loss procedures. However, complications can occur. Strictures at the gastrojejunal anastomosis lead to clinical symptoms such as vomiting, dysphagia, and patient discomfort. The stricture rate has been correlated with the size and type of stapler used. Methods: A retrospective review of the clinical records of patients who underwent LRYGB was performed between 2003 and 2010. A comparison was made between a 21-mm circular stapler technique and a 25-mm linear stapler technique. Results: The stricture rate for the 21-mm circular stapler group was 7.12% and comparable to the national average. Using the 25-mm linear stapler, this complication rate significantly decreased to 1.09% (p<0.0004; odds ratio 6.5; [95% confidence interval 1.96–33.83]). Conclusions: Stricture after LRYGB is a serious complication. This study found that with a change in technique, this complication can be decreased considerably. PMID:25830078

Stricture Rate after Laparoscopic Roux-en-Y Gastric Bypass with a 21-mm Circular Stapler versus a 25-mm Linear Stapler.

PubMed

Baccaro, Leopoldo M; Vunnamadala, Kalyan; Sakharpe, Aniket; Wilhelm, B Jakub; Aksade, Artun

2015-03-01

Background: Obesity is estimated to affect more than one and a half billion adults. Laparoscopic Roux-en-Y gastric bypass (LRYGB) has become one of the preferred weight loss procedures. However, complications can occur. Strictures at the gastrojejunal anastomosis lead to clinical symptoms such as vomiting, dysphagia, and patient discomfort. The stricture rate has been correlated with the size and type of stapler used. Methods: A retrospective review of the clinical records of patients who underwent LRYGB was performed between 2003 and 2010. A comparison was made between a 21-mm circular stapler technique and a 25-mm linear stapler technique. Results: The stricture rate for the 21-mm circular stapler group was 7.12% and comparable to the national average. Using the 25-mm linear stapler, this complication rate significantly decreased to 1.09% ( p <0.0004; odds ratio 6.5; [95% confidence interval 1.96-33.83]). Conclusions: Stricture after LRYGB is a serious complication. This study found that with a change in technique, this complication can be decreased considerably.

Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development.

PubMed

Szabo, Linda; Morey, Robert; Palpant, Nathan J; Wang, Peter L; Afari, Nastaran; Jiang, Chuan; Parast, Mana M; Murry, Charles E; Laurent, Louise C; Salzman, Julia

2015-06-16

The pervasive expression of circular RNA is a recently discovered feature of gene expression in highly diverged eukaryotes, but the functions of most circular RNAs are still unknown. Computational methods to discover and quantify circular RNA are essential. Moreover, discovering biological contexts where circular RNAs are regulated will shed light on potential functional roles they may play. We present a new algorithm that increases the sensitivity and specificity of circular RNA detection by discovering and quantifying circular and linear RNA splicing events at both annotated and un-annotated exon boundaries, including intergenic regions of the genome, with high statistical confidence. Unlike approaches that rely on read count and exon homology to determine confidence in prediction of circular RNA expression, our algorithm uses a statistical approach. Using our algorithm, we unveiled striking induction of general and tissue-specific circular RNAs, including in the heart and lung, during human fetal development. We discover regions of the human fetal brain, such as the frontal cortex, with marked enrichment for genes where circular RNA isoforms are dominant. The vast majority of circular RNA production occurs at major spliceosome splice sites; however, we find the first examples of developmentally induced circular RNAs processed by the minor spliceosome, and an enriched propensity of minor spliceosome donors to splice into circular RNA at un-annotated, rather than annotated, exons. Together, these results suggest a potentially significant role for circular RNA in human development.

Real-Space Mapping of the Chiral Near-Field Distributions in Spiral Antennas and Planar Metasurfaces.

PubMed

Schnell, M; Sarriugarte, P; Neuman, T; Khanikaev, A B; Shvets, G; Aizpurua, J; Hillenbrand, R

2016-01-13

Chiral antennas and metasurfaces can be designed to react differently to left- and right-handed circularly polarized light, which enables novel optical properties such as giant optical activity and negative refraction. Here, we demonstrate that the underlying chiral near-field distributions can be directly mapped with scattering-type scanning near-field optical microscopy employing circularly polarized illumination. We apply our technique to visualize, for the first time, the circular-polarization selective nanofocusing of infrared light in Archimedean spiral antennas, and explain this chiral optical effect by directional launching of traveling waves in analogy to antenna theory. Moreover, we near-field image single-layer rosette and asymmetric dipole-monopole metasurfaces and find negligible and strong chiral optical near-field contrast, respectively. Our technique paves the way for near-field characterization of optical chirality in metal nanostructures, which will be essential for the future development of chiral antennas and metasurfaces and their applications.

Detection and Analysis of Circular RNAs by RT-PCR.

PubMed

Panda, Amaresh C; Gorospe, Myriam

2018-03-20

Gene expression in eukaryotic cells is tightly regulated at the transcriptional and posttranscriptional levels. Posttranscriptional processes, including pre-mRNA splicing, mRNA export, mRNA turnover, and mRNA translation, are controlled by RNA-binding proteins (RBPs) and noncoding (nc)RNAs. The vast family of ncRNAs comprises diverse regulatory RNAs, such as microRNAs and long noncoding (lnc)RNAs, but also the poorly explored class of circular (circ)RNAs. Although first discovered more than three decades ago by electron microscopy, only the advent of high-throughput RNA-sequencing (RNA-seq) and the development of innovative bioinformatic pipelines have begun to allow the systematic identification of circRNAs (Szabo and Salzman, 2016; Panda et al ., 2017b; Panda et al ., 2017c). However, the validation of true circRNAs identified by RNA sequencing requires other molecular biology techniques including reverse transcription (RT) followed by conventional or quantitative (q) polymerase chain reaction (PCR), and Northern blot analysis (Jeck and Sharpless, 2014). RT-qPCR analysis of circular RNAs using divergent primers has been widely used for the detection, validation, and sometimes quantification of circRNAs (Abdelmohsen et al ., 2015 and 2017; Panda et al ., 2017b). As detailed here, divergent primers designed to span the circRNA backsplice junction sequence can specifically amplify the circRNAs and not the counterpart linear RNA. In sum, RT-PCR analysis using divergent primers allows direct detection and quantification of circRNAs.

Circular permutant GFP insertion folding reporters

DOEpatents

Waldo, Geoffrey S [Santa Fe, NM; Cabantous, Stephanie [Los Alamos, NM

2008-06-24

Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The invention further provides various nucleic acid molecules and vectors incorporating such nucleic acid molecules, comprising polynucleotides encoding fluorescent protein circular permutants derived from superfolder GFP, which polynucleotides include an internal cloning site into which a heterologous polynucleotide may be inserted in-frame with the circular permutant coding sequence, and which when expressed are capable of reporting on the degree to which a polypeptide encoded by such an inserted heterologous polynucleotide is correctly folded by correlation with the degree of fluorescence exhibited.

Circular permutant GFP insertion folding reporters

DOEpatents

Waldo, Geoffrey S; Cabantous, Stephanie

2013-02-12

Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The invention further provides various nucleic acid molecules and vectors incorporating such nucleic acid molecules, comprising polynucleotides encoding fluorescent protein circular permutants derived from superfolder GFP, which polynucleotides include an internal cloning site into which a heterologous polynucleotide may be inserted in-frame with the circular permutant coding sequence, and which when expressed are capable of reporting on the degree to which a polypeptide encoded by such an inserted heterologous polynucleotide is correctly folded by correlation with the degree of fluorescence exhibited.

Circular permutant GFP insertion folding reporters

DOEpatents

Waldo, Geoffrey S [Santa Fe, NM; Cabantous, Stephanie [Los Alamos, NM

2011-06-14

Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The invention further provides various nucleic acid molecules and vectors incorporating such nucleic acid molecules, comprising polynucleotides encoding fluorescent protein circular permutants derived from superfolder GFP, which polynucleotides include an internal cloning site into which a heterologous polynucleotide may be inserted in-frame with the circular permutant coding sequence, and which when expressed are capable of reporting on the degree to which a polypeptide encoded by such an inserted heterologous polynucleotide is correctly folded by correlation with the degree of fluorescence exhibited.

Circular permutant GFP insertion folding reporters

DOEpatents

Waldo, Geoffrey S.; Cabantous, Stephanie

2013-04-16

Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The invention further provides various nucleic acid molecules and vectors incorporating such nucleic acid molecules, comprising polynucleotides encoding fluorescent protein circular permutants derived from superfolder GFP, which polynucleotides include an internal cloning site into which a heterologous polynucleotide may be inserted in-frame with the circular permutant coding sequence, and which when expressed are capable of reporting on the degree to which a polypeptide encoded by such an inserted heterologous polynucleotide is correctly folded by correlation with the degree of fluorescence exhibited.

Stokes-Mueller matrix polarimetry technique for circular dichroism/birefringence sensing with scattering effects.

PubMed

Phan, Quoc-Hung; Lo, Yu-Lung

2017-04-01

A surface plasmon resonance (SPR)-enhanced method is proposed for measuring the circular dichroism (CD), circular birefringence (CB), and degree of polarization (DOP) of turbid media using a Stokes–Mueller matrix polarimetry technique. The validity of the analytical model is confirmed by means of numerical simulations. The simulation results show that the proposed detection method enables the CD and CB properties to be measured with a resolution of 10 ? 4 refractive index unit (RIU) and 10 ? 5 ?? RIU , respectively, for refractive indices in the range of 1.3 to 1.4. The practical feasibility of the proposed method is demonstrated by detecting the CB/CD/DOP properties of glucose–chlorophyllin compound samples containing polystyrene microspheres. It is shown that the extracted CB value decreases linearly with the glucose concentration, while the extracted CD value increases linearly with the chlorophyllin concentration. However, the DOP is insensitive to both the glucose concentration and the chlorophyllin concentration. Consequently, the potential of the proposed SPR-enhanced Stokes–Mueller matrix polarimetry method for high-resolution CB/CD/DOP detection is confirmed. Notably, in contrast to conventional SPR techniques designed to detect relative refractive index changes, the SPR technique proposed in the present study allows absolute measurements of the optical properties (CB/CD/DOP) to be obtained.

The Penetration Behavior of an Annular Gas-Solid Jet Impinging on a Liquid Bath: Comparison with a Conventional Circular Jet

NASA Astrophysics Data System (ADS)

Park, Sung Sil; Dyussekenov, Nurzhan; Sohn, H. Y.

2010-02-01

The top-blow injection technique of a gas-solid mixture through a circular lance is used in the Mitsubishi Continuous Smelting Process. One of the inherent problems associated with this injection is the severe erosion of the hearth refractory below the lances. A new configuration of the lance to form an annular gas-solid jet rather than a circular jet was designed in the laboratory scale. With this new configuration, solid particles leave the lance at a much lower velocity than the gas, and the penetration behavior of the jet is significantly different than with the circular lance in which the solid particles leave the lance at the same high velocity as the gas. The results of cold model tests using an air-sand jet issuing from a circular lance and an annular lance into a water bath showed that the penetration of the annular jet is much less sensitive to the variations in particle feed rate as well as gas velocity than that of the circular jet. Correlation equations for the penetration depth for both circular and annular jets show agreement among the experimentally obtained values.

A Wideband Circularly Polarized Antenna with a Multiple-Circular-Sector Dielectric Resonator

PubMed Central

Trinh-Van, Son; Yang, Youngoo; Lee, Kang-Yoon; Hwang, Keum Cheol

2016-01-01

This paper presents the design of a wideband circularly polarized antenna using a multiple-circular-sector dielectric resonator (DR). The DR is composed of twelve circular-sector DRs with identical central angles of 30∘ but with different radii. A genetic algorithm is utilized to optimize the radii of the twelve circular-sector DRs to realize wideband circular polarization. The proposed antenna is excited using an aperture-coupled feeding technique through a narrow rectangular slot etched onto the ground plane. An antenna prototype is experimentally verified. The measured −10 dB reflection and 3 dB axial ratio (AR) bandwidths are 31.39% (1.88–2.58 GHz) and 19.30% (2.06–2.50 GHz), respectively, covering the operating bands of the following systems: UMTS-2100 (2.145 GHz), WiMAX (2.3 GHz), and Wi-Fi (2.445 GHz). A measured peak gain of 7.65 dBic at 2.225 GHz and gain variation of less than 2.70 dBic within the measured 3 dB AR bandwidth are achieved. In addition, the radiation patterns of the proposed antenna are presented and discussed. PMID:27827881

Electron microscope aperture system

NASA Technical Reports Server (NTRS)

Heinemann, K. (Inventor)

1976-01-01

An electron microscope including an electron source, a condenser lens having either a circular aperture for focusing a solid cone of electrons onto a specimen or an annular aperture for focusing a hollow cone of electrons onto the specimen, and an objective lens having an annular objective aperture, for focusing electrons passing through the specimen onto an image plane are described. The invention also entails a method of making the annular objective aperture using electron imaging, electrolytic deposition and ion etching techniques.

TRIPPy: Trailed Image Photometry in Python

NASA Astrophysics Data System (ADS)

Fraser, Wesley; Alexandersen, Mike; Schwamb, Megan E.; Marsset, Michaël; Pike, Rosemary E.; Kavelaars, J. J.; Bannister, Michele T.; Benecchi, Susan; Delsanti, Audrey

2016-06-01

Photometry of moving sources typically suffers from a reduced signal-to-noise ratio (S/N) or flux measurements biased to incorrect low values through the use of circular apertures. To address this issue, we present the software package, TRIPPy: TRailed Image Photometry in Python. TRIPPy introduces the pill aperture, which is the natural extension of the circular aperture appropriate for linearly trailed sources. The pill shape is a rectangle with two semicircular end-caps and is described by three parameters, the trail length and angle, and the radius. The TRIPPy software package also includes a new technique to generate accurate model point-spread functions (PSFs) and trailed PSFs (TSFs) from stationary background sources in sidereally tracked images. The TSF is merely the convolution of the model PSF, which consists of a moffat profile, and super-sampled lookup table. From the TSF, accurate pill aperture corrections can be estimated as a function of pill radius with an accuracy of 10 mmag for highly trailed sources. Analogous to the use of small circular apertures and associated aperture corrections, small radius pill apertures can be used to preserve S/Ns of low flux sources, with appropriate aperture correction applied to provide an accurate, unbiased flux measurement at all S/Ns.

Simple, low-cost fabrication of semi-circular channel using the surface tension of solder paste and its application to microfluidic valves.

PubMed

Yan, Sheng; Li, Yuxing; Zhu, Yuanqing; Liu, Minsu; Zhao, Qianbin; Yuan, Dan; Yun, Guolin; Zhang, Shiwu; Wen, Weijia; Tang, Shi-Yang; Li, Weihua

2018-06-01

This work presents a simple, low-cost method to fabricate semi-circular channels using solder paste, which can amalgamate the cooper surface to form a half-cylinder mold using the surface tension of Sn-Pd alloy (the main component in solder paste). This technique enables semi-circular channels to be manufactured with different dimensions. These semi-circular channels will then be integrated with a polymethylmethacrylate frame and machine screws to create miniaturized, portable microfluidic valves for sequential liquid delivery and particle synthesis. This approach avoids complicated fabrication processes and expensive facilities and thus has the potential to be a useful tool for lab-on-a-chip applications. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Application of program generation technology in solving heat and flow problems

NASA Astrophysics Data System (ADS)

Wan, Shui; Wu, Bangxian; Chen, Ningning

2007-05-01

Based on a new DIY concept for software development, an automatic program-generating technology attached on a software system called as Finite Element Program Generator (FEPG) provides a platform of developing programs, through which a scientific researcher can submit his special physico-mathematical problem to the system in a more direct and convenient way for solution. For solving flow and heat problems by using finite element method, the stabilization technologies and fraction-step methods are adopted to overcome the numerical difficulties caused mainly due to the dominated convection. A couple of benchmark problems are given in this paper as examples to illustrate the usage and the superiority of the automatic program generation technique, including the flow in a lid-driven cavity, the starting flow in a circular pipe, the natural convection in a square cavity, and the flow past a circular cylinder, etc. They are also shown as the verification of the algorithms.

A Model-Based Approach for the Measurement of Eye Movements Using Image Processing

NASA Technical Reports Server (NTRS)

Sung, Kwangjae; Reschke, Millard F.

1997-01-01

This paper describes a video eye-tracking algorithm which searches for the best fit of the pupil modeled as a circular disk. The algorithm is robust to common image artifacts such as the droopy eyelids and light reflections while maintaining the measurement resolution available by the centroid algorithm. The presented algorithm is used to derive the pupil size and center coordinates, and can be combined with iris-tracking techniques to measure ocular torsion. A comparison search method of pupil candidates using pixel coordinate reference lookup tables optimizes the processing requirements for a least square fit of the circular disk model. This paper includes quantitative analyses and simulation results for the resolution and the robustness of the algorithm. The algorithm presented in this paper provides a platform for a noninvasive, multidimensional eye measurement system which can be used for clinical and research applications requiring the precise recording of eye movements in three-dimensional space.

Laser speckle technique to study the effect of chemical pre-treatment on the quality of minimally processed apples

NASA Astrophysics Data System (ADS)

Minz, Preeti D.; Nirala, A. K.

2016-04-01

In the present study, the laser speckle technique has been used for the quality evaluation of chemically treated cut apples. Chemical pre-treatment includes 1% (w/v) solution of citric acid (CA), sodium chloride (SC), and a combination of CA and sodium chloride (CS). The variation in weight loss, respiration rate, total soluble solids (TSS), titratable acidity (TA), and absorbance of chemically treated cut apples stored at 5 °C was monitored for 11 d. The speckle grain size was calculated by an autocovariance method from the speckled images of freshly cut chemically treated apples. The effect of chemicals on TSS and the TA content variation of the cut apples were well correlated to the linear speckle grain size. Circular degree of polarization confirms the presence of a small scatterer and hence Rayleigh diffusion region. For all the treated cut apples, a decrease in the concentration of small particles nearly after the mid-period of storage results in the fast decay of circular degree of polarization. For non-invasive and fast analysis of the chemical constituent of fruits during minimal processing, the laser speckle can be practically used in the food industry.

Experimental investigation of turbulent flow through a circular-to-rectangular transition duct. Ph.D. Thesis - Washington Univ.

NASA Technical Reports Server (NTRS)

Davis, David O.

1991-01-01

Steady, incompressible, turbulent, swirl-free flow through a circular-to-rectangular transition duck was studied experimentally. The cross-sectional area remains the same at the exit as at the inlet, but varies through the transition section to a maximum value approximately 15 percent above the inlet value. The cross-sectional geometry everywhere along the duct is defined by the equation of a superellipse. Mean and turbulence data were accumulated utilizing pressure and hot-wire instrumentation at five stations along the test section. Data are presented for operating bulk Reynolds numbers of 88,000 and 390,000. Measured quantities include total and static pressure, the three components of the mean velocity vector, and the six components of the Reynolds stress tensor. In addition to the transition duct measurements, a hot-wire technique which relies on the sequential use of single rotatable normal and slant-wire probes was proposed. The technique is applicable for measurement of the total mean velocity vector and the complete Reynolds stress tensor when the primary flow is arbitrarily skewed relative to a plane which lies normal to the probe axis of rotation.

Management of paediatric tibial fractures using two types of circular external fixator: Taylor spatial frame and Ilizarov circular fixator.

PubMed

Tafazal, Suhayl; Madan, Sanjeev S; Ali, Farhan; Padman, Manoj; Swift, Simone; Jones, Stanley; Fernandes, James A

2014-05-01

The use of circular fixators for the treatment of tibial fractures is well established in the literature. The aim of this study was to compare the Ilizarov circular fixator (ICF) with the Taylor spatial frame (TSF) in terms of treatment results in consecutive patients with tibial fractures that required operative management. A retrospective analysis of patient records and radiographs was performed to obtain patient data, information on injury sustained, the operative technique used, time duration in frame, healing time and complications of treatment. The minimum follow-up was 24 months. Ten patients were treated with ICF between 2000 and 2005, while 15 patients have been treated with TSF since 2005. Two of the 10 treated with ICF and 5 of the 15 treated with TSF were open fractures. All patients went on to achieve complete union. Mean duration in the frame was 12.7 weeks for ICF and 14.8 weeks for the TSF group. Two patients in the TSF group had delayed union and required additional procedures including adjustment of fixator and bone grafting. There was one malunion in the TSF group that required osteotomy and reapplication of frame. There were seven and nine pin-site infections in the ICF and TSF groups, respectively, all of which responded to antibiotics. There were no refractures in either group. In an appropriate patient, both types of circular fixator are equally effective but have different characteristics, with TSF allowing for postoperative deformity correction. Of concern are the two cases of delayed union in the TSF group, all in patients with high-energy injuries. We feel another larger study is required to provide further clarity in this matter. Level II-comparative study.

Reverse Transrectal Stapling Technique Using the EEA Stapler: An Alternative Approach in Difficult Reversal of Hartmann’s Procedure

PubMed Central

Zachariah, Sanoop K.

2010-01-01

The introduction of circular end-to-end stapling devices (CEEA OR EEA stapler) into colorectal surgery have revolutionised anastomotic techniques. The EEA stapler is generally regarded as an instrument that is safe, reliable, and simple to operate. Despite it’s popularity, very little information is available regarding the technical difficulties encountered during surgery. The routine technique to perform an end-to-end circular colonic anastomosis is to introduce the instrument distally through the anus (transrectal/transanal approach) and attach it to the anvil which is purse stringed at the distal end of the proximal bowel to be anastomosed. Two cases of reversal of Hartmann’s procedure for perforated diverticulitis are described in the present study, where difficulty was experienced while using the EEA stapler in the routine method. Hence, an alternative reverse technique which was used is presented. PMID:22091338

Bandgap-customizable germanium using lithographically determined biaxial tensile strain for silicon-compatible optoelectronics.

PubMed

Sukhdeo, David S; Nam, Donguk; Kang, Ju-Hyung; Brongersma, Mark L; Saraswat, Krishna C

2015-06-29

Strain engineering has proven to be vital for germanium-based photonics, in particular light emission. However, applying a large permanent biaxial tensile strain to germanium has been a challenge. We present a simple, CMOS-compatible technique to conveniently induce a large, spatially homogenous strain in circular structures patterned within germanium nanomembranes. Our technique works by concentrating and amplifying a pre-existing small strain into a circular region. Biaxial tensile strains as large as 1.11% are observed by Raman spectroscopy and are further confirmed by photoluminescence measurements, which show enhanced and redshifted light emission from the strained germanium. Our technique allows the amount of biaxial strain to be customized lithographically, allowing the bandgaps of different germanium structures to be independently customized in a single mask process.

Adaptive design of an X-ray magnetic circular dichroism spectroscopy experiment with Gaussian process modelling

NASA Astrophysics Data System (ADS)

Ueno, Tetsuro; Hino, Hideitsu; Hashimoto, Ai; Takeichi, Yasuo; Sawada, Masahiro; Ono, Kanta

2018-01-01

Spectroscopy is a widely used experimental technique, and enhancing its efficiency can have a strong impact on materials research. We propose an adaptive design for spectroscopy experiments that uses a machine learning technique to improve efficiency. We examined X-ray magnetic circular dichroism (XMCD) spectroscopy for the applicability of a machine learning technique to spectroscopy. An XMCD spectrum was predicted by Gaussian process modelling with learning of an experimental spectrum using a limited number of observed data points. Adaptive sampling of data points with maximum variance of the predicted spectrum successfully reduced the total data points for the evaluation of magnetic moments while providing the required accuracy. The present method reduces the time and cost for XMCD spectroscopy and has potential applicability to various spectroscopies.

Analysis of Near-field of Circular Aperture Antennas with Application to Study of High Intensity Radio Frequency (HIRF) Hazards to Aviation from JPL/NASA Deep Space Network Antennas

NASA Technical Reports Server (NTRS)

Jamnejad, Vahraz; Statman, Joseph

2013-01-01

This work includes a simplified analysis of the radiated near to mid-field from JPL/NASA Deep Space Network (DSN) reflector antennas and uses an averaging technique over the main beam region and beyond for complying with FAA regulations in specific aviation environments. The work identifies areas that require special attention, including the implications of the very narrow beam of the DSN transmitters. The paper derives the maximum averaged power densities allowed and identifies zones where mitigation measures are required.

Circular birefringence/dichroism measurement of optical scattering samples using amplitude-modulation polarimetry

NASA Astrophysics Data System (ADS)

Liu, Wei-Chun; Lo, Yu-Lung; Phan, Quoc-Hung

2018-03-01

A method is proposed for extracting the circular birefringence (CB), circular dichroism (CD) and depolarization (Dep) properties of optical scattering samples using an amplitude-modulation polarimetry technique. The validity of the proposed method is demonstrated by extracting the CB property of pure glucose aqueous samples, the CB/Dep properties of glucose solutions containing 0.02% lipofundin particles, and the CD/Dep properties of chlorophyllin solutions containing suspended polystyrene microspheres. The results show that the proposed technique has the ability to detect pure glucose with a resolution of 66 mg/dL over a concentration range of 0-500 mg/dL. Moreover, the glucose concentration of the CB/Dep samples can be detected over the same range with a resolution of 168 mg/dL. Finally, the chlorophyllin concentration of the CD/Dep sample can be detected over the range of 0-200 μg/dL with a resolution of 6.5 × 10-5. In general, the results show that the proposed technique provides a reliable and accurate means of measuring the CB/CD properties of optical samples with scattering effects, and thus has significant potential for biological sensing applications.

All-dielectric metasurface circular dichroism waveplate.

PubMed

Hu, Jingpei; Zhao, Xiaonan; Lin, Yu; Zhu, Aijiao; Zhu, Xiaojun; Guo, Peiji; Cao, Bing; Wang, Chinhua

2017-01-31

We propose and experimentally demonstrate a high efficient circularly polarizing dichroism waveplate (CPDW) using a Si-based all-dielectric 2Dchiral metasurface. We demonstrate that the CPDW exhibits a unique dichroism in that it functions as a transmissive quarter waveplate for one of either left-or right-handed circularly polarized incident lightand a reflective mirror for the opposite polarization. The circular polarization dichroism (CPD = I RCP  - I LCP ) in transmission at wavelength ~1.5 μm reaches 97% and the extinction ratio (ER = I RCP /I LCP ) is as high as 345:1. Experimental fabrications and measurements of the proposed all-dielectric metasurface are implemented and found to be in excellent agreement with the simulations. The proposed all-dielectric chiral metasurface is of advantages of high-dichroism, easy-fabrication and standard semiconductor fabrication techniques compatible, which could lead to enhanced security in fiber and free-space communications, as well as imaging and sensing applications for circularly polarized light with a highly integrated photonic platform.

Experimental investigation of complex circular Airy beam characteristics

NASA Astrophysics Data System (ADS)

Porfirev, A. P.; Fomchenkov, S. A.; Khonina, S. N.

2018-04-01

We demonstrate a new type of circular Airy beams, the so-called azimuthally modulated circular Airy beams, generated by utilizing a diffraction element, whose transmission function is the sum of the transmission function of the element generating a "petal" pattern and the transmission function of the element generating a circular Airy beam. We experimentally investigate the propagation dynamics of such beams and demonstrate that their autofocusing and selfhealing properties are strongly dependent on the number of generated petals. These beams are a combination of a conventional circular Airy beam and vortex laser beams (or their superpositions). Using a spatial light modulator, we demonstrate that these beams have unique properties such as autofocusing, "nondiffractive" propagation and self-healing after passing through an obstacle. The experimental results are in good agreement with the simulation. We believe that these results can be very useful for lensless laser fabrication and laser manipulation techniques, as well as for development of new filament plasma multi-channel formation methods.

A bifunctional amorphous polymer exhibiting equal linear and circular photoinduced birefringences.

PubMed

Royes, Jorge; Provenzano, Clementina; Pagliusi, Pasquale; Tejedor, Rosa M; Piñol, Milagros; Oriol, Luis

2014-11-01

The large and reversible photoinduced linear and circular birefringences in azo-compounds are at the basis of the interest in these materials, which are potentially useful for several applications. Since the onset of the linear and circular anisotropies relies on orientational processes, which typically occur on the molecular and supramolecular length scale, respectively, a circular birefringence at least one order of magnitude lower than the linear one is usually observed. Here, the synthesis and characterization of an amorphous polymer with a dimeric repeating unit containing a cyanoazobenzene and a cyanobiphenyl moiety are reported, in which identical optical linear and circular birefringences are induced for proper light dose and ellipticity. A pump-probe technique and an analytical method based on the Stokes-Mueller formalism are used to investigate the photoinduced effects and to evaluate the anisotropies. The peculiar photoresponse of the polymer makes it a good candidate for applications in smart functional devices. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

All-dielectric metasurface circular dichroism waveplate

PubMed Central

Hu, Jingpei; Zhao, Xiaonan; Lin, Yu; Zhu, Aijiao; Zhu, Xiaojun; Guo, Peiji; Cao, Bing; Wang, Chinhua

2017-01-01

We propose and experimentally demonstrate a high efficient circularly polarizing dichroism waveplate (CPDW) using a Si-based all-dielectric 2Dchiral metasurface. We demonstrate that the CPDW exhibits a unique dichroism in that it functions as a transmissive quarter waveplate for one of either left-or right-handed circularly polarized incident lightand a reflective mirror for the opposite polarization. The circular polarization dichroism (CPD = IRCP − ILCP) in transmission at wavelength ~1.5 μm reaches 97% and the extinction ratio (ER = IRCP/ILCP) is as high as 345:1. Experimental fabrications and measurements of the proposed all-dielectric metasurface are implemented and found to be in excellent agreement with the simulations. The proposed all-dielectric chiral metasurface is of advantages of high-dichroism, easy-fabrication and standard semiconductor fabrication techniques compatible, which could lead to enhanced security in fiber and free-space communications, as well as imaging and sensing applications for circularly polarized light with a highly integrated photonic platform. PMID:28139753

A complete three-dimensional reconstruction of the myoanatomy of Loricifera: comparative morphology of an adult and a Higgins larva stage.

PubMed

Neves, Ricardo C; Bailly, Xavier; Leasi, Francesca; Reichert, Heinrich; Sørensen, Martin V; Kristensen, Reinhardt M

2013-04-15

Loricifera is a group of small, marine animals, with undetermined phylogenetic relationships within Ecdysozoa (molting protostome animals). Despite their well-known external morphology, data on the internal anatomy of loriciferans are still incomplete. Aiming to increase the knowledge of this enigmatic phylum, we reconstruct for the first time the three-dimensional myoanatomy of loriciferans. Adult Nanaloricus sp. and the Higgins larva of Armorloricus elegans were investigated with cytochemical labeling techniques and CLSM. We discuss our findings with reference to other loriciferan species and recently established phylogenies. The somatic musculature of both adult and larval stages is very complex and includes several muscles arranged in three orientations: circular, transverse and longitudinal. In adult Nanaloricus sp., the introvert is characterized by a net-like muscular arrangement, which is composed of five thin circular fibers crossed by several (up to 30) thin longitudinal fibers with bifurcated anterior ends. Two sets of muscles surround the pre-pharyngeal armature: 6 buccal tube retractors arranged 3 × 2 in a conical shaped structure, and 8 mouth cone retractors. Additionally, a thick, circular muscle marks the neck region and a putative anal sphincter is the posteriormost myoanatomical feature. In the Higgins larva of A. elegans, two circular muscles are distinguished anteriorly in the introvert: a dorsal semicircular fiber and a thin ring muscle. The posteriormost region of the body is characterized by an anal sphincter and a triangular muscle. Based on the currently available knowledge, the myoanatomical bodyplan of adult loriciferans includes: (i) 8 mouth cone retractors, (ii) a pharynx bulb composed of transversal fibers arranged radially, (iii) circular muscles of the head and neck, (iv) internal muscles of the spinoscalids, (v) longitudinal muscles spanning all body regions, and (vi) transverse (circular) muscles in the abdomen. Concerning the Higgins larva, the muscle subsets assigned to its myoanatomical ground pattern are the (i) longitudinal retractors of the mouth cone, introvert, and abdomen, (ii) abdominal transverse muscles, and (iii) a pharynx bulb composed of transverse, radial fibers. In a comparison with phyla traditionally regarded as phylogenetically close, our data show that the overall myoanatomy of Loricifera is more similar to Kinorhyncha and Nematomorpha than to Priapulida. However, the head musculature of all these groups is very similar, which supports homology of their introverts and head morphology.

A complete three-dimensional reconstruction of the myoanatomy of Loricifera: comparative morphology of an adult and a Higgins larva stage

PubMed Central

2013-01-01

Introduction Loricifera is a group of small, marine animals, with undetermined phylogenetic relationships within Ecdysozoa (molting protostome animals). Despite their well-known external morphology, data on the internal anatomy of loriciferans are still incomplete. Aiming to increase the knowledge of this enigmatic phylum, we reconstruct for the first time the three-dimensional myoanatomy of loriciferans. Adult Nanaloricus sp. and the Higgins larva of Armorloricus elegans were investigated with cytochemical labeling techniques and CLSM. We discuss our findings with reference to other loriciferan species and recently established phylogenies. Results The somatic musculature of both adult and larval stages is very complex and includes several muscles arranged in three orientations: circular, transverse and longitudinal. In adult Nanaloricus sp., the introvert is characterized by a net-like muscular arrangement, which is composed of five thin circular fibers crossed by several (up to 30) thin longitudinal fibers with bifurcated anterior ends. Two sets of muscles surround the pre-pharyngeal armature: 6 buccal tube retractors arranged 3 × 2 in a conical shaped structure, and 8 mouth cone retractors. Additionally, a thick, circular muscle marks the neck region and a putative anal sphincter is the posteriormost myoanatomical feature. In the Higgins larva of A. elegans, two circular muscles are distinguished anteriorly in the introvert: a dorsal semicircular fiber and a thin ring muscle. The posteriormost region of the body is characterized by an anal sphincter and a triangular muscle. Conclusions Based on the currently available knowledge, the myoanatomical bodyplan of adult loriciferans includes: (i) 8 mouth cone retractors, (ii) a pharynx bulb composed of transversal fibers arranged radially, (iii) circular muscles of the head and neck, (iv) internal muscles of the spinoscalids, (v) longitudinal muscles spanning all body regions, and (vi) transverse (circular) muscles in the abdomen. Concerning the Higgins larva, the muscle subsets assigned to its myoanatomical ground pattern are the (i) longitudinal retractors of the mouth cone, introvert, and abdomen, (ii) abdominal transverse muscles, and (iii) a pharynx bulb composed of transverse, radial fibers. In a comparison with phyla traditionally regarded as phylogenetically close, our data show that the overall myoanatomy of Loricifera is more similar to Kinorhyncha and Nematomorpha than to Priapulida. However, the head musculature of all these groups is very similar, which supports homology of their introverts and head morphology. PMID:23587092

Ring-oven based preconcentration technique for microanalysis: simultaneous determination of Na, Fe, and Cu in fuel ethanol by laser induced breakdown spectroscopy.

PubMed

Cortez, Juliana; Pasquini, Celio

2013-02-05

The ring-oven technique, originally applied for classical qualitative analysis in the years 1950s to 1970s, is revisited to be used in a simple though highly efficient and green procedure for analyte preconcentration prior to its determination by the microanalytical techniques presently available. The proposed preconcentration technique is based on the dropwise delivery of a small volume of sample to a filter paper substrate, assisted by a flow-injection-like system. The filter paper is maintained in a small circular heated oven (the ring oven). Drops of the sample solution diffuse by capillarity from the center to a circular area of the paper substrate. After the total sample volume has been delivered, a ring with a sharp (c.a. 350 μm) circular contour, of about 2.0 cm diameter, is formed on the paper to contain most of the analytes originally present in the sample volume. Preconcentration coefficients of the analyte can reach 250-fold (on a m/m basis) for a sample volume as small as 600 μL. The proposed system and procedure have been evaluated to concentrate Na, Fe, and Cu in fuel ethanol, followed by simultaneous direct determination of these species in the ring contour, employing the microanalytical technique of laser induced breakdown spectroscopy (LIBS). Detection limits of 0.7, 0.4, and 0.3 μg mL(-1) and mean recoveries of (109 ± 13)%, (92 ± 18)%, and (98 ± 12)%, for Na, Fe, and Cu, respectively, were obtained in fuel ethanol. It is possible to anticipate the application of the technique, coupled to modern microanalytical and multianalyte techniques, to several analytical problems requiring analyte preconcentration and/or sample stabilization.

Premixer assembly for mixing air and fuel for combustion

DOEpatents

York, William David; Johnson, Thomas Edward; Keener, Christopher Paul

2016-12-13

A premixer assembly for mixing air and fuel for combustion includes a plurality of tubes disposed at a head end of a combustor assembly. Also included is a tube of the plurality of tubes, the tube including an inlet end and an outlet end. Further included is at least one non-circular portion of the tube extending along a length of the tube, the at least one non-circular portion having a non-circular cross-section, and the tube having a substantially constant cross-sectional area along its length

Method of forming aperture plate for electron microscope

NASA Technical Reports Server (NTRS)

Heinemann, K. (Inventor)

1974-01-01

An electron microscope is described with an electron source a condenser lens having either a circular aperture for focusing a solid cone of electrons onto a specimen or an annular aperture for focusing a hollow cone of electrons onto the specimen. It also has objective lens with an annular objective aperture, for focusing electrons passing through the specimen onto an image plane. A method of making the annular objective aperture using electron imaging, electrolytic deposition and ion etching techniques is included.

Compact waveguide circular polarizer

DOEpatents

Tantawi, Sami G.

2016-08-16

A multi-port waveguide is provided having a rectangular waveguide that includes a Y-shape structure with first top arm having a first rectangular waveguide port, a second top arm with second rectangular waveguide port, and a base arm with a third rectangular waveguide port for supporting a TE.sub.10 mode and a TE.sub.20 mode, where the end of the third rectangular waveguide port includes rounded edges that are parallel to a z-axis of the waveguide, a circular waveguide having a circular waveguide port for supporting a left hand and a right hand circular polarization TE.sub.11 mode and is coupled to a base arm broad wall, and a matching feature disposed on the base arm broad wall opposite of the circular waveguide for terminating the third rectangular waveguide port, where the first rectangular waveguide port, the second rectangular waveguide port and the circular waveguide port are capable of supporting 4-modes of operation.

Holographic Reconstruction of Photoelectron Diffraction and Its Circular Dichroism for Local Structure Probing

NASA Astrophysics Data System (ADS)

Matsui, Fumihiko; Matsushita, Tomohiro; Daimon, Hiroshi

2018-06-01

The local atomic structure around a specific element atom can be recorded as a photoelectron diffraction pattern. Forward focusing peaks and diffraction rings around them indicate the directions and distances from the photoelectron emitting atom to the surrounding atoms. The state-of-the-art holography reconstruction algorithm enables us to image the local atomic arrangement around the excited atom in a real space. By using circularly polarized light as an excitation source, the angular momentum transfer from the light to the photoelectron induces parallax shifts in these diffraction patterns. As a result, stereographic images of atomic arrangements are obtained. These diffraction patterns can be used as atomic-site-resolved probes for local electronic structure investigation in combination with spectroscopy techniques. Direct three-dimensional atomic structure visualization and site-specific electronic property analysis methods are reviewed. Furthermore, circular dichroism was also found in valence photoelectron and Auger electron diffraction patterns. The investigation of these new phenomena provides hints for the development of new techniques for local structure probing.

Method for changing the cross section of a laser beam

DOEpatents

Sweatt, W.C.; Seppala, L.

1995-12-05

A technique is disclosed herein in which a circular optical beam, for example a copper vapor laser (CVL) beam, is converted to a beam having a profile other than circular, e.g. square or triangular. This is accomplished by utilizing a single optical mirror having a reflecting surface designed in accordance with a specifically derived formula in order to make the necessary transformation, without any substantial light loss and without changing substantially the intensity profile of the circular beam which has a substantially uniform intensity profile. In this way, the output beam can be readily directed into the dye cell of a dye laser. 4 figs.

Method for changing the cross section of a laser beam

DOEpatents

Sweatt, William C.; Seppala, Lynn

1995-01-01

A technique is disclosed herein in which a circular optical beam, for example a copper vapor laser (CVL) beam, is converted to a beam having a profile other than circular, e.g. square or triangular. This is accomplished by utilizing a single optical mirror having a reflecting surface designed in accordance with a specifically derived formula in order to make the necessary transformation, without any substantial light loss and without changing substantially the intensity profile of the circular beam which has a substantially uniform intensity profile. In this way, the output beam can be readily directed into the dye cell of a dye laser.

Time-resolved circular dichroism: Application to the study of conformal changes in biomolecules

NASA Astrophysics Data System (ADS)

Hache, F.

2010-06-01

Circular dichroism (CD) is known to be a very sensitive probe of the conformation of molecules and biomolecules. It is therefore tempting to implement CD in a pump-probe experiment in order to measure ultrarapid conformational changes which occur in photochemical processes. We present two technical developments of such time-resolved CD experiments. The first one relies on the modulation of the probe polarization from left to right circular whereas the second one measures the pump-induced ellipticity of the probe with a Babinet-Soleil compensator. Some applications are described and extension of these techniques towards the study of elementary protein folding processes is discussed.

Simple circular odor chart for characterization of trace amounts of odorants discharged from thirteen odor sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoshika, Y.; Nihei, Y.; Muto, G.

1981-04-01

A simple circular odor chart is proposed for the explanation of the relationship between sensory responses (to odor quality and intensity) to odors and chemical analysis data of the odorants responsible for each odor discharged from thirteen odor sources. The odorants were classified into eight odorant groups and were analyzed by a systematic gas chromatographic (GC) technique. The characterization of the trace amounts of the odorants was carried out by using the values of a new proposed unit (pOU) based on the ratio of detected concentration to recognition threshold value. The calculated pOU values of the eight groups were plottedmore » in circular charts. It was found that the shape and size of each circular odor chart represent the quality and the intensity of each odor.« less

Near shot-noise limited time-resolved circular dichroism pump-probe spectrometer

NASA Astrophysics Data System (ADS)

Stadnytskyi, Valentyn; Orf, Gregory S.; Blankenship, Robert E.; Savikhin, Sergei

2018-03-01

We describe an optical near shot-noise limited time-resolved circular dichroism (TRCD) pump-probe spectrometer capable of reliably measuring circular dichroism signals in the order of μdeg with nanosecond time resolution. Such sensitivity is achieved through a modification of existing TRCD designs and introduction of a new data processing protocol that eliminates approximations that have caused substantial nonlinearities in past measurements and allows the measurement of absorption and circular dichroism transients simultaneously with a single pump pulse. The exceptional signal-to-noise ratio of the described setup makes the TRCD technique applicable to a large range of non-biological and biological systems. The spectrometer was used to record, for the first time, weak TRCD kinetics associated with the triplet state energy transfer in the photosynthetic Fenna-Matthews-Olson antenna pigment-protein complex.

Robotic surgery of locally advanced gastric cancer: a single-surgeon experience of 41 cases.

PubMed

Vasilescu, C; Procopiuc, L

2012-01-01

The mainstay of curative gastric cancer treatment is open gastric resection with regional lymph node dissection. Minimally invasive surgery is yet to become an established technique with a well defined role. Robotic surgery has by-passed some of the limitations of conventional laparoscopy and has proven both safe and feasible. We present our initial experience with robotic surgery based on 41 gastric cancer patients. We especially wish to underline the advantages of the robotic system when performing the digestive tract anastomoses. We present the techniques of end-to-side eso-jejunoanastomoses (using a circular stapler or manual suture) and side-to-side eso-jejunoanastomoses. In our hands, the results with circular stapled anastomoses were good and we advocate against manual suturing when performing anastomoses in robotic surgery. Moreover, we recommend performing totally intracorporeal anastomoses which have a better post-operative outcome, especially in obese patients. We present three methods of realising the total intracorporeal eso-jejuno-anastomosis with a circular stapler: manual purse-string suture, using the OrVil and the double stapling technique. The eso-jejunoanastomosis is one of the most difficult steps in performing the total gastrectomy, but these techniques allow the surgeon to choose the best option for each case. We consider that surgeons who undertake total gastrectomies must have a special training in performing these anastomoses.

Advancements of two dimensional correlation spectroscopy in protein researches

NASA Astrophysics Data System (ADS)

Tao, Yanchun; Wu, Yuqing; Zhang, Liping

2018-05-01

The developments of two-dimensional correlation spectroscopy (2DCOS) applications in protein studies are discussed, especially for the past two decades. The powerful utilities of 2DCOS combined with various analytical techniques in protein studies are summarized. The emphasis is on the vibration spectroscopic techniques including IR, NIR, Raman and optical activity (ROA), as well as vibration circular dichroism (VCD) and fluorescence spectroscopy. In addition, some new developments, such as hetero-spectral 2DCOS, moving-window correlation, and model based correlation, are also reviewed for their utility in the investigation of the secondary structure, denaturation, folding and unfolding changes of protein. Finally, the new possibility and challenges of 2DCOS in protein research are highlighted as well.

Phase-tuning Metasurface for Circularly Polarized Broadside Radiation in Broadband.

PubMed

Zhang, Youfei; Wang, Haogang; Liao, Dashuang; Fu, Weijie

2018-02-14

Metasurface antennas (MAs) have been proposed as innovative alternatives to conventional bulky configurations for satellite applications because of their low profile, low cost, and high gain. The general method of surface impedance modulation for designing MAs is complicated, and achieving broad operation bandwidth remains a challenge because of its high dispersion response. We propose a novel and easy technique to control cylindrical surface waves radiated by a phase-tuning metasurface. Simultaneously, this technique exhibits a considerably wide working bandwidth. A detailed analysis of the radiation mechanism is discussed. A left-hand circularly polarized (LHCP) antenna and a right-hand circularly polarized (RHCP) antenna that are based on the phase-tuning metasurface are simulated and measured. The measured fractional 3-dB gain bandwidth and gain are higher than 17% and 15.57 dBi, respectively, which are consistent with the simulated results. Moreover, 30% 3-dB axial ratio is achieved for the LHCP and RHCP antennas. To the best knowledge of the authors, it is for the first time to realize a circularly polarized broadband MA by using the phase-tuning mechanism. The approach can be regarded as a new starting point for antenna design, thereby paving the way for the development of broadband and low-profile antennas for future satellite communication.

Experimental and numerical investigation on heat transfer augmentation in a circular tube under forced convection with annular differential blockages/inserts

NASA Astrophysics Data System (ADS)

Waghole, D. R.

2018-06-01

Investigation on heat transfer by generating turbulence in the fluid stream inside the circular tube is an innovative area of research for researchers. Hence, many techniques are been investigated and adopted for enhancement of heat transfer rate to reduce the size and the cost of the heat exchanger/circular tube. In the present study the effect of differential solid ring inserts /turbulators on heat transfer, friction factor of heat exchanger/circular tube was evaluated through experimentally and numerically. The experiments were conducted in range of 3000 ≤Re≤ 6500 and annular blockages 0 ≤ɸ≤50 %. The heat transfer rate was higher for differential combination of inserts as compared to tube fitted with uniform inserts. The maximum heat transfer was obtained by the use of differential metal circular ring inserts/blockages. From this study, Nusselt number, friction factor and enhancement factor are found as 2.5-3.5 times, 12% - 50.5% and 155% - 195%, respectively with water. Finally new possible correlations for predicting heat transfer and friction factor in the flow of water through the circular tube with differential blockages/inserts are proposed.

Circular Bioassay Platforms for Applications in Microwave-Accelerated Techniques.

PubMed

Mohammed, Muzaffer; Clement, Travis C; Aslan, Kadir

2014-12-02

In this paper, we present the design of four different circular bioassay platforms, which are suitable for homogeneous microwave heating, using theoretical calculations (i.e., COMSOL™ multiphysics software). Circular bioassay platforms are constructed from poly(methyl methacrylate) (PMMA) for optical transparency between 400-800 nm, has multiple sample capacity (12, 16, 19 and 21 wells) and modified with silver nanoparticle films (SNFs) to be used in microwave-accelerated bioassays (MABs). In addition, a small monomode microwave cavity, which can be operated with an external microwave generator (100 W), for use with the bioassay platforms in MABs is also developed. Our design parameters for the circular bioassay platforms and monomode microwave cavity during microwave heating were: (i) temperature profiles, (ii) electric field distributions, (iii) location of the circular bioassay platforms inside the microwave cavity, and (iv) design and number of wells on the circular bioassay platforms. We have also carried out additional simulations to assess the use of circular bioassay platforms in a conventional kitchen microwave oven (e.g., 900 W). Our results show that the location of the circular bioassay platforms in the microwave cavity was predicted to have a significant effect on the homogeneous heating of these platforms. The 21-well circular bioassay platform design in our monomode microwave cavity was predicted to offer a homogeneous heating pattern, where inter-well temperature was observed to be in between 23.72-24.13°C and intra-well temperature difference was less than 0.21°C for 60 seconds of microwave heating, which was also verified experimentally.

Circular Bioassay Platforms for Applications in Microwave-Accelerated Techniques

PubMed Central

Mohammed, Muzaffer; Clement, Travis C.; Aslan, Kadir

2014-01-01

In this paper, we present the design of four different circular bioassay platforms, which are suitable for homogeneous microwave heating, using theoretical calculations (i.e., COMSOL™ multiphysics software). Circular bioassay platforms are constructed from poly(methyl methacrylate) (PMMA) for optical transparency between 400–800 nm, has multiple sample capacity (12, 16, 19 and 21 wells) and modified with silver nanoparticle films (SNFs) to be used in microwave-accelerated bioassays (MABs). In addition, a small monomode microwave cavity, which can be operated with an external microwave generator (100 W), for use with the bioassay platforms in MABs is also developed. Our design parameters for the circular bioassay platforms and monomode microwave cavity during microwave heating were: (i) temperature profiles, (ii) electric field distributions, (iii) location of the circular bioassay platforms inside the microwave cavity, and (iv) design and number of wells on the circular bioassay platforms. We have also carried out additional simulations to assess the use of circular bioassay platforms in a conventional kitchen microwave oven (e.g., 900 W). Our results show that the location of the circular bioassay platforms in the microwave cavity was predicted to have a significant effect on the homogeneous heating of these platforms. The 21-well circular bioassay platform design in our monomode microwave cavity was predicted to offer a homogeneous heating pattern, where inter-well temperature was observed to be in between 23.72–24.13°C and intra-well temperature difference was less than 0.21°C for 60 seconds of microwave heating, which was also verified experimentally. PMID:25568813

Conjugate gradient determination of optimal plane changes for a class of three-impulse transfers between noncoplanar circular orbits

NASA Technical Reports Server (NTRS)

Burrows, R. R.

1972-01-01

A particular type of three-impulse transfer between two circular orbits is analyzed. The possibility of three plane changes is recognized, and the problem is to optimally distribute these plane changes to minimize the sum of the individual impulses. Numerical difficulties and their solution are discussed. Numerical results obtained from a conjugate gradient technique are presented for both the case where the individual plane changes are unconstrained and for the case where they are constrained. Possibly not unexpectedly, multiple minima are found. The techniques presented could be extended to the finite burn case, but primarily the contents are addressed to preliminary mission design and vehicle sizing.

Finite element techniques applied to cracks interacting with selected singularities

NASA Technical Reports Server (NTRS)

Conway, J. C.

1975-01-01

The finite-element method for computing the extensional stress-intensity factor for cracks approaching selected singularities of varied geometry is described. Stress-intensity factors are generated using both displacement and J-integral techniques, and numerical results are compared to those obtained experimentally in a photoelastic investigation. The selected singularities considered are a colinear crack, a circular penetration, and a notched circular penetration. Results indicate that singularities greatly influence the crack-tip stress-intensity factor as the crack approaches the singularity. In addition, the degree of influence can be regulated by varying the overall geometry of the singularity. Local changes in singularity geometry have little effect on the stress-intensity factor for the cases investigated.

A Brief History of Limb Lengthening.

PubMed

Birch, John G

2017-09-01

In the last 35 years, orthopaedic surgeons have witnessed 3 major advances in the technique of limb lengthening: "distraction osteogenesis" facilitated by Gavriil Ilizarov method and infinitely-adaptable circular fixator with fine-wire bone fragment fixation; the introduction of the "6-strut" computer program-assisted circular fixators to effect complex deformity correction simultaneously; and the development of motorized intramedullary lengthening nails. However, the principles and associated complications of these techniques are on the basis of observations by Codivilla, Putti, and Abbott from as much as 110 years ago. This review notes the contribution of these pioneers in limb lengthening, and the contribution of Thor Heyerdahl principles of tolerance and diversity to the dissemination of Ilizarov principles to the Western world.

Altering the orientation of a fused protein to the RNA-binding ribosomal protein L7Ae and its derivatives through circular permutation.

PubMed

Ohuchi, Shoji J; Sagawa, Fumihiko; Sakamoto, Taiichi; Inoue, Tan

2015-10-23

RNA-protein complexes (RNPs) are useful for constructing functional nano-objects because a variety of functional proteins can be displayed on a designed RNA scaffold. Here, we report circular permutations of an RNA-binding protein L7Ae based on the three-dimensional structure information to alter the orientation of the displayed proteins on the RNA scaffold. An electrophoretic mobility shift assay and atomic force microscopy (AFM) analysis revealed that most of the designed circular permutants formed an RNP nano-object. Moreover, the alteration of the enhanced green fluorescent protein (EGFP) orientation was confirmed with AFM by employing EGFP on the L7Ae permutant on the RNA. The results demonstrate that targeted fine-tuning of the stereo-specific fixation of a protein on a protein-binding RNA is feasible by using the circular permutation technique. Copyright © 2015 Elsevier Inc. All rights reserved.

Searching for Models Exhibiting High Circularly Polarized Luminescence: the Electroactive Inherently Chiral Oligothiophenes.

PubMed

Benincori, Tiziana; Appoloni, Giulio; Mussini, Patrizia Romana; Arnaboldi, Serena; Cirilli, Roberto; Quartapelle Procopio, Elsa; Panigati, Monica; Abbate, Sergio; Mazzeo, Giuseppe; Longhi, Giovanna

2018-05-02

Two new inherently chiral oligothiophenes characterized by the atropisomeric 3,3'-bithianaphtene scaffold functionalized with fused ring bithiophene derivatives, namely 4H-cyclopenta [2,1-b3:4b']dithiophene (CPDT) and dithieno[3,3-b:2',3'-d]pyrrole (DTP), were synthesized. The racemates were fully characterized and resolved into antipodes by enantioselective HPLC. The enantiomers were analyzed through different chiroptical techniques: electronic circular dichroism (ECD) and vibrational circular dichroism (VCD) were employed to attribute the absolute configuration (AC). Comparison of experimental and calculated VCD spectra confirmed the DFT calculated conformational characteristics. The compound functionalized with two CPDT units was oxidized with FeCl3 and ECD and CPL of the resulting material were measured. Circularly Polarized Luminescence (CPL) was measured in order to verify if inherently chiral oligothiophenes could be promising systems for chiral photonics applications. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

A novel finite element analysis of three-dimensional circular crack

NASA Astrophysics Data System (ADS)

Ping, X. C.; Wang, C. G.; Cheng, L. P.

2018-06-01

A novel singular element containing a part of the circular crack front is established to solve the singular stress fields of circular cracks by using the numerical series eigensolutions of singular stress fields. The element is derived from the Hellinger-Reissner variational principle and can be directly incorporated into existing 3D brick elements. The singular stress fields are determined as the system unknowns appearing as displacement nodal values. The numerical studies are conducted to demonstrate the simplicity of the proposed technique in handling fracture problems of circular cracks. The usage of the novel singular element can avoid mesh refinement near the crack front domain without loss of calculation accuracy and velocity of convergence. Compared with the conventional finite element methods and existing analytical methods, the present method is more suitable for dealing with complicated structures with a large number of elements.

Analysis of a disk-on-rod surface wave element inside a corrugated horn using the mode-matching technique

NASA Technical Reports Server (NTRS)

Chen, J. C.

1995-01-01

A disk-on-rod inside a corrugated horn is one of the horn configurations for dual-frequency or wide-band operation. A mode-matching analysis method is described. A disk-on-rod inside a corrugated horn is represented as a series of coaxial waveguide sections and circular waveguide sections connected to each other. Three kinds of junctions need to be considered: coaxial-to-coaxial, coaxial-to-circular, and circular-to-circular. A computer program was developed to calculate the scattering matrix and the radiation pattern of a disk-on-rod inside a corrugated horn. The software as verified by experiment, and good agreement between calculation and measurement was obtained. The disk-on-rod inside a corrugated horn design gives an option to the Deep Space Network dual-frequency operation system, which currently is a two-horn/one-dichroic plate system.

Altering the orientation of a fused protein to the RNA-binding ribosomal protein L7Ae and its derivatives through circular permutation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ohuchi, Shoji J.; Sagawa, Fumihiko; Sakamoto, Taiichi

RNA-protein complexes (RNPs) are useful for constructing functional nano-objects because a variety of functional proteins can be displayed on a designed RNA scaffold. Here, we report circular permutations of an RNA-binding protein L7Ae based on the three-dimensional structure information to alter the orientation of the displayed proteins on the RNA scaffold. An electrophoretic mobility shift assay and atomic force microscopy (AFM) analysis revealed that most of the designed circular permutants formed an RNP nano-object. Moreover, the alteration of the enhanced green fluorescent protein (EGFP) orientation was confirmed with AFM by employing EGFP on the L7Ae permutant on the RNA. Themore » results demonstrate that targeted fine-tuning of the stereo-specific fixation of a protein on a protein-binding RNA is feasible by using the circular permutation technique.« less

Statistics based sampling for controller and estimator design

NASA Astrophysics Data System (ADS)

Tenne, Dirk

The purpose of this research is the development of statistical design tools for robust feed-forward/feedback controllers and nonlinear estimators. This dissertation is threefold and addresses the aforementioned topics nonlinear estimation, target tracking and robust control. To develop statistically robust controllers and nonlinear estimation algorithms, research has been performed to extend existing techniques, which propagate the statistics of the state, to achieve higher order accuracy. The so-called unscented transformation has been extended to capture higher order moments. Furthermore, higher order moment update algorithms based on a truncated power series have been developed. The proposed techniques are tested on various benchmark examples. Furthermore, the unscented transformation has been utilized to develop a three dimensional geometrically constrained target tracker. The proposed planar circular prediction algorithm has been developed in a local coordinate framework, which is amenable to extension of the tracking algorithm to three dimensional space. This tracker combines the predictions of a circular prediction algorithm and a constant velocity filter by utilizing the Covariance Intersection. This combined prediction can be updated with the subsequent measurement using a linear estimator. The proposed technique is illustrated on a 3D benchmark trajectory, which includes coordinated turns and straight line maneuvers. The third part of this dissertation addresses the design of controller which include knowledge of parametric uncertainties and their distributions. The parameter distributions are approximated by a finite set of points which are calculated by the unscented transformation. This set of points is used to design robust controllers which minimize a statistical performance of the plant over the domain of uncertainty consisting of a combination of the mean and variance. The proposed technique is illustrated on three benchmark problems. The first relates to the design of prefilters for a linear and nonlinear spring-mass-dashpot system and the second applies a feedback controller to a hovering helicopter. Lastly, the statistical robust controller design is devoted to a concurrent feed-forward/feedback controller structure for a high-speed low tension tape drive.

Experimental investigation of laminar flow of viscous oil through a circular tube having integral axial corrugation roughness and fitted with twisted tapes with oblique teeth

NASA Astrophysics Data System (ADS)

Pal, Sagnik; Saha, Sujoy Kumar

2015-08-01

The experimental friction factor and Nusselt number data for laminar flow of viscous oil through a circular duct having integral axial corrugation roughness and fitted with twisted tapes with oblique teeth have been presented. Predictive friction factor and Nusselt number correlations have also been presented. The thermohydraulic performance has been evaluated. The major findings of this experimental investigation are that the twisted tapes with oblique teeth in combination with integral axial corrugation roughness perform significantly better than the individual enhancement technique acting alone for laminar flow through a circular duct up to a certain value of fin parameter.

Color visualization of cyclic magnitudes

NASA Astrophysics Data System (ADS)

Restrepo, Alfredo; Estupiñán, Viviana

2014-02-01

We exploit the perceptual, circular ordering of the hues in a technique for the visualization of cyclic variables. The hue is thus meaningfully used for the indication of variables such as the azimuth and the units of the measurement of time. The cyclic (or circular) variables may be both of the continuous type or the discrete type; among the first there is azimuth and among the last you find the musical notes and the days of the week. A correspondence between the values of a cyclic variable and the chromatic hues, where the natural circular ordering of the variable is respected, is called a color code for the variable. We base such a choice of hues on an assignment of of the unique hues red, yellow, green and blue, or one of the 8 even permutations of this ordered list, to 4 cardinal values of the cyclic variable, suitably ordered; color codes based on only 3 cardinal points are also possible. Color codes, being intuitive, are easy to remember. A possible low accuracy when reading instruments that use this technique is compensated by fast, ludic and intuitive readings; also, the use of a referential frame makes readings precise. An achromatic version of the technique, that can be used by dichromatic people, is proposed.

A Safe and Reproducible Anastomotic Technique for Minimally Invasive Ivor Lewis Esophagectomy: The Circular Stapled Anastomosis with the Transoral Anvil

PubMed Central

Campos, Guilherme M; Jablons, David; Brown, Lisa M; Ramirez, René M; Rabl, Charlotte; Theodore, Pierre

2010-01-01

Objectives In expert hands, the intra-thoracic esophago-gastric anastamosis usually provides a low rate of strictures and leaks. However, anastomoses can be technically challenging and time consuming when minimally invasive techniques are used. We present our preliminary results of a standardized 25mm/4.8mm circular stapled anastomosis using a trans-orally placed anvil. Materials and Methods We evaluated a prospective cohort of 37 consecutive patients offered minimally invasive Ivor Lewis Esophagectomy at a tertiary referral center. The esophagogastric anastomosis was created using a 25mm anvil (Orvil, Autosuture, Norwalk, CT) passed trans-orally, in a tilted position, and connected to a 90cm long PVC delivery tube through an opening in the esophageal stump. The anastomosis was completed by joining the anvil to a circular stapler (EEA XL 25mm with 4.8mm Staples, Autosuture, Norwalk, CT) inserted into the gastric conduit. Primary outcomes were leak and stricture rates. Results Thirty-seven patients (mean age 65 yrs) with distal esophageal adenocarcinoma (n=29), squamous cell cancer (n=5), or high-grade dysplasia in Barrett's Esophagus (n=3) underwent an Ivor Lewis Esophagectomy between October 2007 and August 2009. The abdominal portion of the operation was completed laparoscopically in 30 patients (81.1%). The thoracic portion was done using a muscle sparing mini-thoracotomy in 23 patients (62.2%) and thoracoscopic techniques in 14 patients (37.8%). There were no intra-operative technical failures of the anastomosis or deaths. Five patients had strictures (13.5%) and all were successfully treated with endoscopic dilations. One patient had an anastomotic leak (2.7%) that was successfully treated by re-operation and endoscopic stenting of the anastomosis. Discussion The circular stapled anastomosis with the transoral anvil allows for an efficient, safe and reproducible anastomosis. This straightforward technique is particularly suited to the completely minimally invasive Ivor Lewis Esophagectomy. PMID:20153660

A New Limit on CMB Circular Polarization from SPIDER

DOE PAGES

Nagy, J. M.; Ade, P. A. R.; Amiri, M.; ...

2017-08-01

We present a new upper limit on CMB circular polarization from the 2015 flight of SPIDER, a balloon-borne telescope designed to search formore » $B$-mode linear polarization from cosmic inflation. Although the level of circular polarization in the CMB is predicted to be very small, experimental limits provide a valuable test of the underlying models. By exploiting the non-zero circular-to-linear polarization coupling of the HWP polarization modulators, data from SPIDER's 2015 Antarctic flight provides a constraint on Stokes $V$ at 95 and 150 GHz from $$33<\\ell<307$$. No other limits exist over this full range of angular scales, and SPIDER improves upon the previous limit by several orders of magnitude, providing 95% C.L. constraints on $$\\ell (\\ell+1)C_{\\ell}^{VV}/(2\\pi)$$ ranging from 141 $$\\mu K ^2$$ to 203 $$\\mu K ^2$$ at 150 GHz for a thermal CMB spectrum. As linear CMB polarization experiments become increasingly sensitive, the techniques described in this paper can be applied to obtain stronger constraints on circular polarization.« less

Comparative Study of Hand-Sutured versus Circular Stapled Anastomosis for Gastrojejunostomy in Laparoscopy Assisted Distal Gastrectomy.

PubMed

Seo, Su Hyun; Kim, Ki Han; Kim, Min Chan; Choi, Hong Jo; Jung, Ghap Joong

2012-06-01

Mechanical stapler is regarded as a good alternative to the hand sewing technique, when used in gastric reconstruction. The circular stapling method has been widely applied to gastrectomy (open orlaparoscopic), for gastric cancer. We illustrated and compared the hand-sutured method to the circular stapling method, for Billroth-II, in patients who underwent laparoscopy assisted distal gastrectomy for gastric cancer. Between April 2009 and May 2011, 60 patients who underwent laparoscopy assisted distal gastrectomy, with Billroth-II, were enrolled. Hand-sutured Billroth-II was performed in 40 patients (manual group) and circular stapler Billroth-II was performed in 20 patients (stapler group). Clinicopathological features and post-operative outcomes were evaluated and compared between the two groups. Nosignificant differences were observed in clinicopathologic parameters and post-operative outcomes, except in the operation times. Operation times and anastomosis times were significantly shorter in the stapler group (P=0.004 and P<0.001). Compared to the hand-sutured method, the circular stapling method can be applied safely and more efficiently, when performing Billroth-II anastomosis, after laparoscopy assisted distal gastrectomy in patients with gastric cancer.

A New Limit on CMB Circular Polarization from SPIDER

NASA Astrophysics Data System (ADS)

Nagy, J. M.; Ade, P. A. R.; Amiri, M.; Benton, S. J.; Bergman, A. S.; Bihary, R.; Bock, J. J.; Bond, J. R.; Bryan, S. A.; Chiang, H. C.; Contaldi, C. R.; Doré, O.; Duivenvoorden, A. J.; Eriksen, H. K.; Farhang, M.; Filippini, J. P.; Fissel, L. M.; Fraisse, A. A.; Freese, K.; Galloway, M.; Gambrel, A. E.; Gandilo, N. N.; Ganga, K.; Gudmundsson, J. E.; Halpern, M.; Hartley, J.; Hasselfield, M.; Hilton, G.; Holmes, W.; Hristov, V. V.; Huang, Z.; Irwin, K. D.; Jones, W. C.; Kuo, C. L.; Kermish, Z. D.; Li, S.; Mason, P. V.; Megerian, K.; Moncelsi, L.; Morford, T. A.; Netterfield, C. B.; Nolta, M.; Padilla, I. L.; Racine, B.; Rahlin, A. S.; Reintsema, C.; Ruhl, J. E.; Runyan, M. C.; Ruud, T. M.; Shariff, J. A.; Soler, J. D.; Song, X.; Trangsrud, A.; Tucker, C.; Tucker, R. S.; Turner, A. D.; Van Der List, J. F.; Weber, A. C.; Wehus, I. K.; Wiebe, D. V.; Young, E. Y.

2017-08-01

We present a new upper limit on cosmic microwave background (CMB) circular polarization from the 2015 flight of Spider, a balloon-borne telescope designed to search for B-mode linear polarization from cosmic inflation. Although the level of circular polarization in the CMB is predicted to be very small, experimental limits provide a valuable test of the underlying models. By exploiting the nonzero circular-to-linear polarization coupling of the half-wave plate polarization modulators, data from Spider's 2015 Antarctic flight provide a constraint on Stokes V at 95 and 150 GHz in the range 33< {\\ell }< 307. No other limits exist over this full range of angular scales, and Spider improves on the previous limit by several orders of magnitude, providing 95% C.L. constraints on {\\ell }({\\ell }+1){C}{\\ell }{VV}/(2π ) ranging from 141 to 255 μK2 at 150 GHz for a thermal CMB spectrum. As linear CMB polarization experiments become increasingly sensitive, the techniques described in this paper can be applied to obtain even stronger constraints on circular polarization.

A New Limit on CMB Circular Polarization from SPIDER

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nagy, J. M.; Ade, P. A. R.; Amiri, M.

Here, we present a new upper limit on cosmic microwave background (CMB) circular polarization from the 2015 flight of Spider, a balloon-borne telescope designed to search for B-mode linear polarization from cosmic inflation. Although the level of circular polarization in the CMB is predicted to be very small, experimental limits provide a valuable test of the underlying models. By exploiting the nonzero circular-to-linear polarization coupling of the half-wave plate polarization modulators, data from Spider's 2015 Antarctic flight provide a constraint on Stokes V at 95 and 150 GHz in the rangemore » $$33\\lt {\\ell }\\lt 307$$. No other limits exist over this full range of angular scales, and Spider improves on the previous limit by several orders of magnitude, providing 95% C.L. constraints on $${\\ell }({\\ell }+1){C}_{{\\ell }}^{{VV}}/(2\\pi )$$ ranging from 141 to 255 μK 2 at 150 GHz for a thermal CMB spectrum. In conclusion, as linear CMB polarization experiments become increasingly sensitive, the techniques described in this paper can be applied to obtain even stronger constraints on circular polarization.« less

A New Limit on CMB Circular Polarization from SPIDER

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nagy, J. M.; Ade, P. A. R.; Amiri, M.

We present a new upper limit on CMB circular polarization from the 2015 flight of SPIDER, a balloon-borne telescope designed to search formore » $B$-mode linear polarization from cosmic inflation. Although the level of circular polarization in the CMB is predicted to be very small, experimental limits provide a valuable test of the underlying models. By exploiting the non-zero circular-to-linear polarization coupling of the HWP polarization modulators, data from SPIDER's 2015 Antarctic flight provides a constraint on Stokes $V$ at 95 and 150 GHz from $$33<\\ell<307$$. No other limits exist over this full range of angular scales, and SPIDER improves upon the previous limit by several orders of magnitude, providing 95% C.L. constraints on $$\\ell (\\ell+1)C_{\\ell}^{VV}/(2\\pi)$$ ranging from 141 $$\\mu K ^2$$ to 203 $$\\mu K ^2$$ at 150 GHz for a thermal CMB spectrum. As linear CMB polarization experiments become increasingly sensitive, the techniques described in this paper can be applied to obtain stronger constraints on circular polarization.« less

49 CFR 256.11 - Applications.

Code of Federal Regulations, 2011 CFR

2011-10-01

... accordance with appendix M of Office of Management and Budget Circular A-102, applicants shall use the pre... appendix M of Office of Management and Budget Circular A-102. Applicants shall include under Part IV... of Management and Budget Circular A-102, adequate procedures for financial control, accounting, and...

Visualization of the contact line during the water exit of flat plates

NASA Astrophysics Data System (ADS)

Tassin, A.; Breton, T.; Forest, B.; Ohana, J.; Chalony, S.; Le Roux, D.; Tancray, A.

2017-08-01

We investigate experimentally the time evolution of the wetted surface during the lifting of a body initially floating at the water surface. This phenomenon is referred to as the water exit problem. The water exit experiments were conducted with transparent (PMMA) mock-ups of two different shapes: a circular disc and a square flat plate. Two different lighting systems were used to diffuse light in the mock-up material: a central high-power LED light normal to the surface and an edge-lighting system featuring an array of LED lights. These setups make it possible to illuminate the contact line, which delimits the surface of contact between the mock-up and the water. The characteristic size of the mock-ups is about 20 cm and the acceleration of the mock-up oscillates between 0 and 25 m/s^2. We show that the central light setup gives satisfactory results for the circular disc and that the edge lighting technique makes it possible to follow a contact line with a time-evolving complex shape (strong changes of convexity) up to 1000 fps. The observations presented in the paper support the possibility of extending this promising technique to more general three-dimensional bodies with arbitrary motion (e.g., including pitch motion).

Research in the Restricted Problems of Three and Four Bodies Final Scientific Report

NASA Technical Reports Server (NTRS)

Richards, Paul B.; Bernstein, Irwin S.; Chai, Winchung A.; Cronin, Jane; Ellis, Jordan; Fine, William E.; Kass, Sheldon; Musa, Samuel A.; Russell, Lawrence H.

1968-01-01

Seven studies have been conducted on research in the existence and nature of solutions of the restricted problems of three and four bodies. The details and results of five of these research investigations have already been published, and the latest two studies will be published shortly. A complete bibliography of publications is included in this report. This research has been primarily qualitative and has yielded new information on the behavior of trajectories near the libration points in the Earth-Moon-Sun and Sun-Jupiter-Saturn systems, and on the existence of periodic trajectories about the libration points of the circular and elliptical restricted four-body models. We have also implemented Birkhoff's normalization process for conservative and nonconservative Hamiltonian systems with equilibrium points. This makes available a technique for analyzing stability properties of certain nonlinear dynamical systems, and we have applied this technique to the circular and elliptical restricted three-body models. A related study was also conducted to determine the feasibility of using cislunar periodic trajectories for various space missions. Preliminary results suggest that this concept is attractive for space flight safety operations in cislunar space. Results of this research will be of interest to mathematicians, particularly those working in ordinary differential equations, dynamical systems and celestial mechanics; to astronomers; and to space guidance and mission analysts.

Adaptive panoramic tomography with a circular rotational movement for the formation of multifocal image layers

NASA Astrophysics Data System (ADS)

Kim, D. S.; Cho, H. S.; Park, Y. O.; Je, U. K.; Hong, D. K.; Choi, S. I.; Koo, Y. S.

2012-02-01

Panoramic radiography with which only structures within a certain image layer are in focus and others out of focus on the panoramic image has become a popular imaging technique especially in dentistry. However, the major drawback to the technique is a mismatch between the structures to be focused and the predefined image layer mainly due to the various shapes and sizes of dental arches and/or to malpositioning of the patient. These result in image quality typically inferior to that obtained using intraoral radiographic techniques. In this paper, to overcome these difficulties, we suggest a new panoramic reconstruction algorithm, the so-called adaptive panoramic tomography ( APT), capable of reconstructing multifocal image layers with no additional exposure. In order to verify the effectiveness of the proposed algorithm, we performed systematic simulation studies with a circular rotational movement and investigated the image performance.

Progression from laparoscopic-assisted to totally laparoscopic distal gastrectomy: comparison of circular stapler (i-DST) and linear stapler (BBT) for intracorporeal anastomosis.

PubMed

Ikeda, Tetsuo; Kawano, Hiroyuki; Hisamatsu, Yuichi; Ando, Koji; Saeki, Hiroshi; Oki, Eiji; Ohga, Takefumi; Kakeji, Yoshihiro; Tsujitani, Shunichi; Kohnoe, Shunji; Maehara, Yoshihiko

2013-01-01

Billroth I (B-I) gastroduodenostomy is an anastomotic procedure that is widely performed after gastric resection for distal gastric cancer. A circular stapler often is used for B-I gastroduodenostomy in open and laparoscopic-assisted distal gastrectomy. Recently, totally laparoscopic distal gastrectomy (TLDG) has been considered less invasive than laparoscopic-assisted gastrectomy, and many institutions performing laparoscopic-assisted distal gastrectomy are trying to progress to TLDG without markedly changing the anastomosis method. The purpose of this report is to introduce the technical details of new methods of intracorporeal gastroduodenostomy using either a circular or linear stapler and to evaluate their technical feasibility and safety. Seventeen patients who underwent TLDG with the intracorporeal double-stapling technique using a circular stapler (n = 7) or the book-binding technique (BBT) using a linear stapler (n = 10) between February 2010 and April 2011 were enrolled in the study. Clinicopathological data, surgical data, and postoperative outcomes were analyzed. There were no intraoperative complications or conversions to open surgery in any of the 17 patients. The usual postoperative complications following gastroduodenostomy, such as anastomotic leakage and stenosis, were not observed. Anastomosis took significantly longer to complete with DST (64 ± 24 min) than with BBT (34 ± 7 min), but more stapler cartridges were needed with BBT than with DST. TLDG using a circular or linear stapler is feasible and safe to perform. DST will enable institutions performing laparoscopic-assisted distal gastrectomy with circular staplers to progress to TLDG without problems, and this progression may be more economical because fewer stapler cartridges are used during surgery. However, if an institution has already been performing δ anastomosis in TLDG but has been experiencing certain issues with δ anastomosis, converting from δ anastomosis to BBT should be beneficial.

Element for use in an inductive coupler for downhole drilling components

DOEpatents

Hall, David R.; Hall, Jr., H. Tracy; Pixton, David S.; Dahlgren, Scott; Fox, Joe; Sneddon, Cameron

2006-08-29

The present invention includes an element for use in an inductive coupler in a downhole component. The element includes a plurality of ductile, generally U-shaped leaves that are electrically conductive. The leaves are less than about 0.0625" thick and are separated by an electrically insulating material. These leaves are aligned so as to form a generally circular trough. The invention also includes an inductive coupler for use in downhole components, the inductive coupler including an annular housing having a recess with a magnetically conductive, electrically insulating (MCEI) element disposed in the recess. The MCEI element includes a plurality of segments where each segment further includes a plurality of ductile, generally U-shaped electrically conductive leaves. Each leaf is less than about 0.0625" thick and separated from the otherwise adjacent leaves by electrically insulating material. The segments and leaves are aligned so as to form a generally circular trough. The inductive coupler further includes an insulated conductor disposed within the generally circular trough. A polymer fills spaces between otherwise adjacent segments, the annular housing, insulated conductor, and further fills the circular trough.

Circular Data Images for Directional Data

NASA Technical Reports Server (NTRS)

Morpet, William J.

2004-01-01

Directional data includes vectors, points on a unit sphere, axis orientation, angular direction, and circular or periodic data. The theoretical statistics for circular data (random points on a unit circle) or spherical data (random points on a unit sphere) are a recent development. An overview of existing graphical methods for the display of directional data is given. Cross-over occurs when periodic data are measured on a scale for the measurement of linear variables. For example, if angle is represented by a linear color gradient changing uniformly from dark blue at -180 degrees to bright red at +180 degrees, the color image will be discontinuous at +180 degrees and -180 degrees, which are the same location. The resultant color would depend on the direction of approach to the cross-over point. A new graphical method for imaging directional data is described, which affords high resolution without color discontinuity from "cross-over". It is called the circular data image. The circular data image uses a circular color scale in which colors repeat periodically. Some examples of the circular data image include direction of earth winds on a global scale, rocket motor internal flow, earth global magnetic field direction, and rocket motor nozzle vector direction vs. time.

Single-Layer Wire Routing.

DTIC Science & Technology

1987-08-01

techniques for routing and testing the rout- ability of designs. The design model is ill- suited for the developement of routing algorithms, but the...circular ordering of ca- bles at a feature endpoint. The arrows de - pict the circular ordering of cables at feature ’ 3 cables endpoints p and q. There can...Figure le -1, whose only proper realizations have size fQ(n 2 ). From a practical standpoint, however, the sketch algorithms do not seem as good. Most

Valley polarization in silicene induced by circularly-polarized resonance light

NASA Astrophysics Data System (ADS)

Cao, Jie; Qi, Fenghua

2017-06-01

In the presence of circularly-polarized resonance light, silicene develops dynamical band gaps in its quasi-energy band structure. Using numerical calculations, our results show that the gap appearing at ħω/2, where ħω is the photon energy. More importantly, we find that these gaps are non-symmetric for two inequivalent valleys. Therefore we can introduce light-controlled valley polarization in these dynamical band gaps. Different valleytronic devices can be realized using this technique.

Evaluation of Wear on Macro-Surface Textures Generated by ns Fiber Laser

NASA Astrophysics Data System (ADS)

Harish, V.; Soundarapandian, S.; Vijayaraghavan, L.; Bharatish, A.

2018-03-01

The demand for improved performance and long term reliability of mechanical systems dictate the use of advanced materials and surface engineering techniques. A small change in the surface topography can lead to substantial improvements in the tribological behaviour of the contact surfaces. One way of altering the surface topography is by surface texturing by introducing dimples or channels on the surfaces. Surface texturing is already a successful technique which finds a wide area of applications ranging from heavy industries to small scale devices. This paper reports the effect of macro texture shapes generated using a nanosecond fiber laser on wear of high carbon chromium steel used in large size bearings having rolling contacts. Circular and square shaped dimples were generated on the surface to assess the effect of sliding velocities on friction coefficient. Graphite was used as solid lubricant to minimise the effect of wear on textured surfaces. The laser parameters such as power, scan speed and passes were optimised to obtain macro circular and square dimples which was characterised using a laser confocal microscope. The friction coefficients of the circular and square dimples were observed to lie in the same range due to minimum wear on the surface. On the contrary, at medium and higher sliding velocities, square dimples exhibited lower friction coefficient values compared to circular dimples. The morphology of textured specimen was characterised using Scanning Electron Microscope.

Spotted star light curve numerical modeling technique and its application to HII 1883 surface imaging

NASA Astrophysics Data System (ADS)

Kolbin, A. I.; Shimansky, V. V.

2014-04-01

We developed a code for imaging the surfaces of spotted stars by a set of circular spots with a uniform temperature distribution. The flux from the spotted surface is computed by partitioning the spots into elementary areas. The code takes into account the passing of spots behind the visible stellar limb, limb darkening, and overlapping of spots. Modeling of light curves includes the use of recent results of the theory of stellar atmospheres needed to take into account the temperature dependence of flux intensity and limb darkening coefficients. The search for spot parameters is based on the analysis of several light curves obtained in different photometric bands. We test our technique by applying it to HII 1883.

A Theoretical and Experimental Study of Acoustic Propagation in Multisectioned Circular Ducts. Ph.D. Thesis

NASA Technical Reports Server (NTRS)

Wyerman, B. R.

1976-01-01

The propagation of plane waves and higher order acoustic modes in a circular multisectioned duct was studied. A unique source array consisting of two concentric rings of sources, providing phase and amplitude control in the radial, as well as circumferential direction, was developed to generate plane waves and both spinning and nonspinning higher order modes. Measurements of attenuation and radial mode shapes were taken with finite length liners inserted between the hard wall sections of an anechoically terminated duct. Materials tested as liners included a glass fiber material and both sintered fiber metals and perforated sheet metals with a honeycomb backing. The fundamental acoustic properties of these materials were studied with emphasis on the attenuation of sound by the liners and the determination of local versus extended reaction behavior for the boundary condition. A search technique was developed to find the complex eigenvalues for a liner under the assumption of a locally reacting boundary condition.

Interaction of Lysozyme with Rhodamine B: A combined analysis of spectroscopic & molecular docking.

PubMed

Millan, Sabera; Satish, Lakkoji; Kesh, Sandeep; Chaudhary, Yatendra S; Sahoo, Harekrushna

2016-09-01

The interaction of Rhodamine B (RB) with Lysozyme (Lys) was investigated by different optical spectroscopic techniques such as absorption, fluorescence, and circular-dichroism (CD), along with molecular docking studies. The fluorescence results (including steady-state and time-resolved mode) revealed that the addition of RB effectively causes strong quenching of intrinsic fluorescence in Lysozyme and mostly, by the static quenching mechanism. Different binding and thermodynamic parameters were calculated at different temperatures and the binding constant value was found to be 2963.54Lmol(-1) at 25°C. The average distance (r0) was found to be 3.31nm according to Förster's theory of non-radiative energy transfer between Lysozyme and RB. The conformational change in Lysozyme during interaction with RB was confirmed from absorbance, synchronous fluorescence, and circular dichroism measurements. Finally, molecular docking studies were done to confirm that the dye binds with Lysozyme. Copyright © 2016 Elsevier B.V. All rights reserved.

Characterization of Glutaredoxin Fe-S Cluster-Binding Interactions Using Circular Dichroism Spectroscopy.

PubMed

Albetel, Angela-Nadia; Outten, Caryn E

2018-01-01

Monothiol glutaredoxins (Grxs) with a conserved Cys-Gly-Phe-Ser (CGFS) active site are iron-sulfur (Fe-S) cluster-binding proteins that interact with a variety of partner proteins and perform crucial roles in iron metabolism including Fe-S cluster transfer, Fe-S cluster repair, and iron signaling. Various analytical and spectroscopic methods are currently being used to monitor and characterize glutaredoxin Fe-S cluster-dependent interactions at the molecular level. The electronic, magnetic, and vibrational properties of the protein-bound Fe-S cluster provide a convenient handle to probe the structure, function, and coordination chemistry of Grx complexes. However, some limitations arise from sample preparation requirements, complexity of individual techniques, or the necessity for combining multiple methods in order to achieve a complete investigation. In this chapter, we focus on the use of UV-visible circular dichroism spectroscopy as a fast and simple initial approach for investigating glutaredoxin Fe-S cluster-dependent interactions. © 2018 Elsevier Inc. All rights reserved.

Single-shot quantum nondemolition measurement of a quantum-dot electron spin using cavity exciton-polaritons

NASA Astrophysics Data System (ADS)

Puri, Shruti; McMahon, Peter L.; Yamamoto, Yoshihisa

2014-10-01

We propose a scheme to perform single-shot quantum nondemolition (QND) readout of the spin of an electron trapped in a semiconductor quantum dot (QD). Our proposal relies on the interaction of the QD electron spin with optically excited, quantum well (QW) microcavity exciton-polaritons. The spin-dependent Coulomb exchange interaction between the QD electron and cavity polaritons causes the phase and intensity response of left circularly polarized light to be different than that of right circularly polarized light, in such a way that the QD electron's spin can be inferred from the response to a linearly polarized probe reflected or transmitted from the cavity. We show that with careful device design it is possible to essentially eliminate spin-flip Raman transitions. Thus a QND measurement of the QD electron spin can be performed within a few tens of nanoseconds with fidelity ˜99.95%. This improves upon current optical QD spin readout techniques across multiple metrics, including speed and scalability.

Genome-wide Discovery of Circular RNAs in the Leaf and Seedling Tissues of Arabidopsis Thaliana

PubMed Central

Dou, Yongchao; Li, Shengjun; Yang, Weilong; Liu, Kan; Du, Qian; Ren, Guodong; Yu, Bin; Zhang, Chi

2017-01-01

Background: Recently, identification and functional studies of circular RNAs, a type of non-coding RNAs arising from a ligation of 3’ and 5’ ends of a linear RNA molecule, were conducted in mammalian cells with the development of RNA-seq technology. Method: Since compared with animals, studies on circular RNAs in plants are less thorough, a genome-wide identification of circular RNA candidates in Arabidopsis was conducted with our own developed bioinformatics tool to several existing RNA-seq datasets specifically for non-coding RNAs. Results: A total of 164 circular RNA candidates were identified from RNA-seq data, and 4 circular RNA transcripts, including both exonic and intronic circular RNAs, were experimentally validated. Interestingly, our results show that circular RNA transcripts are enriched in the photosynthesis system for the leaf tissue and correlated to the higher expression levels of their parent genes. Sixteen out of all 40 genes that have circular RNA candidates are related to the photosynthesis system, and out of the total 146 exonic circular RNA candidates, 63 are found in chloroplast. PMID:29081691

Laser emission from diode-pumped Nd:YAG ceramic waveguide lasers realized by direct femtosecond-laser writing technique.

PubMed

Salamu, Gabriela; Jipa, Florin; Zamfirescu, Marian; Pavel, Nicolaie

2014-03-10

We report on realization of buried waveguides in Nd:YAG ceramic media by direct femtosecond-laser writing technique and investigate the waveguides laser emission characteristics under the pump with fiber-coupled diode lasers. Laser pulses at 1.06 μm with energy of 2.8 mJ for the pump with pulses of 13.1-mJ energy and continuous-wave output power of 0.49 W with overall optical efficiency of 0.13 were obtained from a 100-μm diameter circular cladding waveguide realized in a 0.7-at.% Nd:YAG ceramic. A circular waveguide of 50-μm diameter yielded laser pulses at 1.3 μm with 1.2-mJ energy.

Hard X-ray polarizer to enable simultaneous three-dimensional nanoscale imaging of magnetic structure and lattice strain

DOE PAGES

Logan, Jonathan; Harder, Ross; Li, Luxi; ...

2016-01-01

Recent progress in the development of dichroic Bragg coherent diffractive imaging, a new technique for simultaneous three-dimensional imaging of strain and magnetization at the nanoscale, is reported. This progress includes the installation of a diamond X-ray phase retarder at beamline 34-ID-C of the Advanced Photon Source. Here, the performance of the phase retarder for tuning X-ray polarization is demonstrated with temperature-dependent X-ray magnetic circular dichroism measurements on a gadolinium foil in transmission and on a Gd 5Si 2Ge 2crystal in diffraction geometry with a partially coherent, focused X-ray beam. Feasibility tests for dichroic Bragg coherent diffractive imaging are presented. Thesemore » tests include (1) using conventional Bragg coherent diffractive imaging to determine whether the phase retarder introduces aberrations using a nonmagnetic gold nanocrystal as a control sample, and (2) collecting coherent diffraction patterns of a magnetic Gd 5Si 2Ge 2nanocrystal with left- and right-circularly polarized X-rays. Future applications of dichroic Bragg coherent diffractive imaging for the correlation of strain and lattice defects with magnetic ordering and inhomogeneities are considered.« less

Discussion Technique: The Twice-Around

ERIC Educational Resources Information Center

Andersen, Kent

2013-01-01

In this article, the author offers a discussion technique: the twice-around. A variant on the circular response discussion, the twice-around engages students by beginning with students' questions, ensuring equal time for all participants and inviting discussants to build on previous contributions. In the twice-around, participants sit in a circle,…

76 FR 60357 - Federal Regulations; OMB Circulars, OFPP Policy Letters, and CASB Cost Accounting Standards...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-29

... derived from 41 U.S.C. 1501. Cost Accounting Standards are rules governing the measurement, assignment... Circulars, OFPP Policy Letters, and CASB Cost Accounting Standards Included in the Semiannual Agenda of..., and Cost Accounting Standards Board (CASB) Cost Accounting Standards. OMB Circulars and OFPP Policy...

A Study of Failure Characteristics in Thermoplastic Composite Laminates Due to an Eccentric Circular Discontinuity

DTIC Science & Technology

1989-12-01

Bose, Ohio Appni’-sd for puauc t&cw 189 12 29 023 I [ AFIT /GAE /ENY/ 89D-06 A STUDY OF FAILURE CHARACTERISTICS IN THERMOPLASTIC COMPOSITE LAMINATES DUE...distribution unlimited I ,I AFIT / GAE / ENY /89D-06 A STUDY OF FAILURE CHARACTERISTICS IN THERMOPLASTIC COMPOSITE LAMINATES DUE TO AN ECCENTRIC CIRCULAR...the Flight Dynamics Laboratory. Dr. Sandhu provided me with an insight into composite materials, and testing techniques, that will benefit me for a

Spin-Resolved Circularly Polarised Resonant Photoemission: Cu as a Model System

NASA Astrophysics Data System (ADS)

Brookes, N. B.

A brief introduction to the technique of spin resolved resonant photoemission using circularly polarised soft x-rays is given. The method is illustrated by considering the simple case of Cu2+. Starting from CuO we show how the same ideas can be applied to more complex and interesting cases, such as the model compound Sr2CuO2Cl2 and an optimally doped high temperature superconductor, Bi2Sr2CaCu2O8+δ.

Proceedings of the Annual Symposium on Frequency Control (45th) held in Los Angeles, California on May 29 -31, 1991

DTIC Science & Technology

1991-05-31

Corporation High Precision Nonlinear Computer Modelling Technique for Quartz Crystal Oscillators ............... 341 R. Brendel, F. Djian, CNRS & E. Robert...34) A.1.5% IV.1 Results of the computations for resonators having circular electrodes. The model was applied to compute the resonances 0f-.I frequencies...having circular electrodes. *- I The model was applied to compute the resonances frequencies of the fundamental mode and of its anharmonics ,odel and

Quasi-Optical Techniques for Millimeter and Submillimeter-Wave Circuits.

DTIC Science & Technology

1981-03-25

permits non-destructive measurement. The cross section of the IS guide is shown in Fig. 4. We create a notch -type grating in the dielectric strip (rl). Then...the e-igenvalue equation is solved. 1he method was modified to minAlyze .a circular patch radiatlng st ructulre. l’ht, prote dtlrc i s essentIalIv...34Hankel transform domain analysis of open circular microstrip radiating structures," IEEE Trans. Antennas and Propagation, Vol. AP-29, Jan. 1981. 19. T

Novel On-wafer Radiation Pattern Measurement Technique for MEMS Actuator Based Reconfigurable Patch Antennas

NASA Technical Reports Server (NTRS)

Simons, Rainee N.

2002-01-01

The paper presents a novel on-wafer, antenna far field pattern measurement technique for microelectromechanical systems (MEMS) based reconfigurable patch antennas. The measurement technique significantly reduces the time and the cost associated with the characterization of printed antennas, fabricated on a semiconductor wafer or dielectric substrate. To measure the radiation patterns, the RF probe station is modified to accommodate an open-ended rectangular waveguide as the rotating linearly polarized sampling antenna. The open-ended waveguide is attached through a coaxial rotary joint to a Plexiglas(Trademark) arm and is driven along an arc by a stepper motor. Thus, the spinning open-ended waveguide can sample the relative field intensity of the patch as a function of the angle from bore sight. The experimental results include the measured linearly polarized and circularly polarized radiation patterns for MEMS-based frequency reconfigurable rectangular and polarization reconfigurable nearly square patch antennas, respectively.

Density Fluctuation in Asymmetric Nozzle Plumes and Correlation with Far Field Noise

NASA Technical Reports Server (NTRS)

Panda, J.; Zaman, K. B. M. Q.

2001-01-01

A comparative experimental study of air density fluctuations in the unheated plumes of a circular, 4-tabbed-circular, chevron-circular and 10-lobed rectangular nozzles was performed at a fixed Mach number of 0.95 using a recently developed Rayleigh scattering based technique. Subsequently, the flow density fluctuations are cross-correlated with the far field sound pressure fluctuations to determine sources for acoustics emission. The nearly identical noise spectra from the baseline circular and the chevron nozzles are found to be in agreement with the similarity in spreading, turbulence fluctuations, and flow-sound correlations measured in the plumes. The lobed nozzle produced the least low frequency noise, in agreement with the weakest overall density fluctuations and flow-sound correlation. The tabbed nozzle took an intermediate position in the hierarchy of noise generation, intensity of turbulent fluctuation and flow-sound correlation. Some of the features in the 4-tabbed nozzle are found to be explainable in terms of splitting of the jet in a central large core and 4 side jetlets.

Superficial heat reduction technique for a hybrid microwave-optical device.

PubMed

Al-Armaghany, A; Tong, K; Leung, T S

2013-01-01

Microwave applicator in the form of a circularly polarized microstrip patch antenna is proposed to provide localized deep heating in biological tissue, which causes blood vessels to dilate leading to changes in tissue oxygenation. These changes are monitored by an integrated optical system for studying thermoregulation in different parts of the human body. Using computer simulations, this paper compares circularly and linearly polarized antennas in terms of the efficiency of depositing electromagnetic (EM) energy and the heating patterns. The biological model composes of the skin, fat and muscle layers with appropriate dielectric and thermal properties. The results show that for the same specific absorption rate (SAR) in the muscle, the circularly polarized antenna results in a lower SAR in the skin-fat interface than the linearly polarized antenna. The thermal distribution is also presented based on the biological heat equation. The proposed circularly polarized antenna shows heat reduction in the superficial layers in comparison to the linearly polarized antenna.

Comparative Study of Hand-Sutured versus Circular Stapled Anastomosis for Gastrojejunostomy in Laparoscopy Assisted Distal Gastrectomy

PubMed Central

Seo, Su Hyun; Kim, Min Chan; Choi, Hong Jo; Jung, Ghap Joong

2012-01-01

Purpose Mechanical stapler is regarded as a good alternative to the hand sewing technique, when used in gastric reconstruction. The circular stapling method has been widely applied to gastrectomy (open orlaparoscopic), for gastric cancer. We illustrated and compared the hand-sutured method to the circular stapling method, for Billroth-II, in patients who underwent laparoscopy assisted distal gastrectomy for gastric cancer. Materials and Methods Between April 2009 and May 2011, 60 patients who underwent laparoscopy assisted distal gastrectomy, with Billroth-II, were enrolled. Hand-sutured Billroth-II was performed in 40 patients (manual group) and circular stapler Billroth-II was performed in 20 patients (stapler group). Clinicopathological features and post-operative outcomes were evaluated and compared between the two groups. Results Nosignificant differences were observed in clinicopathologic parameters and post-operative outcomes, except in the operation times. Operation times and anastomosis times were significantly shorter in the stapler group (P=0.004 and P<0.001). Conclusions Compared to the hand-sutured method, the circular stapling method can be applied safely and more efficiently, when performing Billroth-II anastomosis, after laparoscopy assisted distal gastrectomy in patients with gastric cancer. PMID:22792525

Reconstruction of the jejunoesophageal anastomosis with a circular mechanical stapler in total laryngopharyngectomy defects.

PubMed

Schneider, Daniel S; Gross, Neil D; Sheppard, Brett C; Wax, Mark K

2012-05-01

The aim of this study was to demonstrate the technical feasibility and potential benefits of using a circular mechanical stapler with free jejunal transfer for jejunoesophageal anastomosis in total laryngopharyngectomy reconstruction while comparing the rates of fistula and stricture. This study was a retrospective review of 12 free jejunal flaps completed with circular mechanical stapler for the jejunoesophageal anastomosis with comparison to 17 jejunal free flaps where all anastomoses were hand sewn. In all, 29 patients underwent free jejunal transfer: 12 had jejunal free flap with circular mechanical stapler for jejunoesophageal anastomosis, whereas 17 patients had hand-sewn anastomosis. Corresponding rates of fistula and stricture were 0/12 fistulas and 3/12 strictures in the stapler cohort and 2/17 fistulas with 0/17 strictures in the hand-sewn cohort. No statistically significant difference in rate of fistula was observed between each cohort, whereas a trend toward increased rate of stricture (p = .06) was observed in the stapled anastomosis cohort. Use of circular mechanical stapler appears to be a safe and effective technique at the jejunoesophageal anastomosis for total laryngopharyngeal defects with comparable fistula and stricture rates to grafts that are hand sewn. Copyright © 2011 Wiley Periodicals, Inc.

Strong variable linear polarization in the cool active star II Peg

NASA Astrophysics Data System (ADS)

Rosén, Lisa; Kochukhov, Oleg; Wade, Gregg A.

2014-08-01

Magnetic fields of cool active stars are currently studied polarimetrically using only circular polarization observations. This provides limited information about the magnetic field geometry since circular polarization is only sensitive to the line-of-sight component of the magnetic field. Reconstructions of the magnetic field topology will therefore not be completely trustworthy when only circular polarization is used. On the other hand, linear polarization is sensitive to the transverse component of the magnetic field. By including linear polarization in the reconstruction the quality of the reconstructed magnetic map is dramatically improved. For that reason, we wanted to identify cool stars for which linear polarization could be detected at a level sufficient for magnetic imaging. Four active RS CVn binaries, II Peg, HR 1099, IM Peg, and σ Gem were observed with the ESPaDOnS spectropolarimeter at the Canada-France-Hawaii Telescope. Mean polarization profiles in all four Stokes parameters were derived using the multi-line technique of least-squares deconvolution (LSD). Not only was linear polarization successfully detected in all four stars in at least one observation, but also, II Peg showed an extraordinarily strong linear polarization signature throughout all observations. This qualifies II Peg as the first promising target for magnetic Doppler imaging in all four Stokes parameters and, at the same time, suggests that other such targets can possibly be identified.

Crack displacement sensing and measurement in concrete using circular grating moire fringes and pattern matching

NASA Astrophysics Data System (ADS)

Chan, H. M.; Yen, K. S.; Ratnam, M. M.

2008-09-01

The moire method has been extensively studied in the past and applied in various engineering applications. Several techniques are available for generating the moire fringes in these applications, which include moire interferometry, projection moire, shadow moire, moire deflectometry etc. Most of these methods use the superposition of linear gratings to generate the moire patterns. The use of non-linear gratings, such as circular, radial and elongated gratings has received less attention from the research community. The potential of non-linear gratings in engineering measurement has been realized in a limited number of applications, such as rotation measurement, measurement of linear displacement, measurement of expansion coefficients of materials and measurement of strain distribution. In this work, circular gratings of different pitch were applied to the sensing and measurement of crack displacement in concrete structures. Gratings of pitch 0.50 mm and 0.55 mm were generated using computer software and attached to two overlapping acrylic plates that were bonded to either side of the crack. The resulting moire patterns were captured using a standard digital camera and compared with a set of reference patterns generated using a precision positioning stage. Using several image pre-processing stages, such as filtering and morphological operations, and pattern matching the magnitude displacements along two orthogonal axes can be detected with a resolution of 0.05 mm.

Combinatorial control of Drosophila circular RNA expression by intronic repeats, hnRNPs, and SR proteins

PubMed Central

Kramer, Marianne C.; Liang, Dongming; Tatomer, Deirdre C.; Gold, Beth; March, Zachary M.; Cherry, Sara; Wilusz, Jeremy E.

2015-01-01

Thousands of eukaryotic protein-coding genes are noncanonically spliced to produce circular RNAs. Bioinformatics has indicated that long introns generally flank exons that circularize in Drosophila, but the underlying mechanisms by which these circular RNAs are generated are largely unknown. Here, using extensive mutagenesis of expression plasmids and RNAi screening, we reveal that circularization of the Drosophila laccase2 gene is regulated by both intronic repeats and trans-acting splicing factors. Analogous to what has been observed in humans and mice, base-pairing between highly complementary transposable elements facilitates backsplicing. Long flanking repeats (∼400 nucleotides [nt]) promote circularization cotranscriptionally, whereas pre-mRNAs containing minimal repeats (<40 nt) generate circular RNAs predominately after 3′ end processing. Unlike the previously characterized Muscleblind (Mbl) circular RNA, which requires the Mbl protein for its biogenesis, we found that Laccase2 circular RNA levels are not controlled by Mbl or the Laccase2 gene product but rather by multiple hnRNP (heterogeneous nuclear ribonucleoprotein) and SR (serine–arginine) proteins acting in a combinatorial manner. hnRNP and SR proteins also regulate the expression of other Drosophila circular RNAs, including Plexin A (PlexA), suggesting a common strategy for regulating backsplicing. Furthermore, the laccase2 flanking introns support efficient circularization of diverse exons in Drosophila and human cells, providing a new tool for exploring the functional consequences of circular RNA expression across eukaryotes. PMID:26450910

Analysis of three-dimensional-cavity-backed aperture antennas using a Combined Finite Element Method/Method of Moments/Geometrical Theory of Diffraction technique

NASA Technical Reports Server (NTRS)

Reddy, C. J.; Deshpande, M. D.; Cockrell, C. R.; Beck, F. B.

1995-01-01

A combined finite element method (FEM) and method of moments (MoM) technique is presented to analyze the radiation characteristics of a cavity-fed aperture in three dimensions. Generalized feed modeling has been done using the modal expansion of fields in the feed structure. Numerical results for some feeding structures such as a rectangular waveguide, circular waveguide, and coaxial line are presented. The method also uses the geometrical theory of diffraction (GTD) to predict the effect of a finite ground plane on radiation characteristics. Input admittance calculations for open radiating structures such as a rectangular waveguide, a circular waveguide, and a coaxial line are shown. Numerical data for a coaxial-fed cavity with finite ground plane are verified with experimental data.

TIDAL STIRRING OF SATELLITES WITH SHALLOW DENSITY PROFILES PREVENTS THEM FROM BEING TOO BIG TO FAIL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tomozeiu, Mihai; Mayer, Lucio; Quinn, Thomas, E-mail: mihai@physik.uzh.ch

The “too big to fail” problem is revisited by studying the tidal evolution of populations of dwarf satellites with different density profiles. The high-resolution cosmological ΛCDM “ErisMod” set of simulations is used. These simulations can model both the stellar and dark matter components of the satellites, and their evolution under the action of the tides of a Milky Way (MW)-sized host halo at a force resolution better than 10 pc. The stronger tidal mass loss and re-shaping of the mass distribution induced in satellites with γ = 0.6 dark matter density distributions, as those resulting from the effect of feedbackmore » in hydrodynamical simulations of dwarf galaxy formation, are sufficient to bring the circular velocity profiles in agreement with the kinematics of MW’s dSphs. In contrast, in simulations in which the satellites retain cusps at z = 0 there are several “massive failures” with circular velocities in excess of the observational constraints. Various sources of deviations in the conventionally adopted relation between the circular velocity at the half-light radius and the one-dimensional line of sight velocity dispersions are found. Such deviations are caused by the response of circular velocity profiles to tidal effects, which also varies depending on the initially assumed inner density profile and by the complexity of the stellar kinematics, which include residual rotation and anisotropy. In addition, tidal effects naturally induce large deviations in the stellar mass–halo mass relation for halo masses below 10{sup 9} M {sub ⊙}, preventing any reliable application of the abundance matching technique to dwarf galaxy satellites.« less

The development of laser speckle velocimetry for the study of vortical flows

NASA Technical Reports Server (NTRS)

Krothapalli, A.

1991-01-01

A research program was undertaken to develop a new experimental technique commonly known as particle image displacement velocity (PIVD) to measure an instantaneous two dimensional velocity field in a selected plane of flow field. This technique was successfully developed and applied to the study of several aerodynamic problems. A detailed description of the technique and a broad review of all the research activity carried out in this field are reported. A list of technical publications is also provided. The application of PIDV to unsteady flows with large scale structures is demonstrated in a study of the temporal evolution of the flow past an impulsively started circular cylinder. The instantaneous two dimensional flow in the transition region of a rectangular air jet was measured using PIDV and the details are presented. This experiment clearly demonstrates the PIDV capability in the measurement of turbulent flows. Preliminary experiments were also conducted to measure the instantaneous flow over a circular bump in a transonic flow. Several other experiments now routinely use PIDV as a non-intrustive measurement technique to obtain instantaneous two dimensional velocity fields.

Synthesis of concentric circular antenna arrays using dragonfly algorithm

NASA Astrophysics Data System (ADS)

Babayigit, B.

2018-05-01

Due to the strong non-linear relationship between the array factor and the array elements, concentric circular antenna array (CCAA) synthesis problem is challenging. Nature-inspired optimisation techniques have been playing an important role in solving array synthesis problems. Dragonfly algorithm (DA) is a novel nature-inspired optimisation technique which is based on the static and dynamic swarming behaviours of dragonflies in nature. This paper presents the design of CCAAs to get low sidelobes using DA. The effectiveness of the proposed DA is investigated in two different (with and without centre element) cases of two three-ring (having 4-, 6-, 8-element or 8-, 10-, 12-element) CCAA design. The radiation pattern of each design cases is obtained by finding optimal excitation weights of the array elements using DA. Simulation results show that the proposed algorithm outperforms the other state-of-the-art techniques (symbiotic organisms search, biogeography-based optimisation, sequential quadratic programming, opposition-based gravitational search algorithm, cat swarm optimisation, firefly algorithm, evolutionary programming) for all design cases. DA can be a promising technique for electromagnetic problems.

Circular Stapler-Assisted Extraperitoneal Colostomy in Laparoscopic Abdominoperineal Resection: a Single Surgeon Experience.

PubMed

Zhang, Peng; Bai, Jie; Shuai, Xiaoming; Chang, Weilong; Gao, Jinbo; Liu, Xinghua; Wang, Guobin; Tao, Kaixiong

2016-03-01

Nowadays, laparoscopic abdominoperineal resection (LAPR) not only has the same oncologic safety of open surgery and but also has the common advantages of laparoscopic surgery. However, given the difficulty in operation and long operative time, laparoscopic extraperitoneal colostomy construction is rarely practiced and reported. In this study, we describe technique of extraperitoneal colostomy using circular stapler following LAPR and demonstrate its efficacy and safety. This is a retrospective analysis of prospectively maintained data of 42 patients who underwent LAPR with circular stapler-assisted extraperitoneal colostomy in our department between July 2011 and June 2014. The mean time for extraperitoneal colostomy construction was 25 min (18-33 min). The mean operative time, estimated blood loss, postoperative gastrointestinal function recovery time, and duration of postoperative hospital stay were 160 min (115-225 min), 45 ml (10-250 ml), 33 h (26-45 h), and 8.6 days (6-13 days), respectively; 4.8 % of the patients had postoperative short-term complications. There were no stenosis, prolapse, and parastomal hernia observed in follow-up period. At 6 months after operation, 26 patients (62 %) claimed to be satisfied with their postoperative stool habits, 29 patients (69 %) had sensation to defecate per stoma, and 11 (26.2 %) patients had the ability to defer defecation for solid or liquid stool per stoma. Circular stapler-assisted extraperitoneal colostomy is an easy, effective, and safe technique following LAPR and appears to minimize the occurrence of stomal complications and improve the quality of life for patients.

Phased array antenna matching: Simulation and optimization of a planar phased array of circular waveguide elements

NASA Technical Reports Server (NTRS)

Dudgeon, J. E.

1972-01-01

A computerized simulation of a planar phased array of circular waveguide elements is reported using mutual coupling and wide angle impedance matching in phased arrays. Special emphasis is given to circular polarization. The aforementioned computer program has as variable inputs: frequency, polarization, grid geometry, element size, dielectric waveguide fill, dielectric plugs in the waveguide for impedance matching, and dielectric sheets covering the array surface for the purpose of wide angle impedance matching. Parameter combinations are found which produce reflection peaks interior to grating lobes, while dielectric cover sheets are successfully employed to extend the usable scan range of a phased array. The most exciting results came from the application of computer aided optimization techniques to the design of this type of array.

Methods and means of 3D diffuse Mueller-matrix tomography of depolarizing optically anisotropic biological layers

NASA Astrophysics Data System (ADS)

Dubolazov, O. V.; Ushenko, V. O.; Trifoniuk, L.; Ushenko, Yu. O.; Zhytaryuk, V. G.; Prydiy, O. G.; Grytsyuk, M.; Kushnerik, L.; Meglinskiy, I.

2017-09-01

A new technique of Mueller-matrix mapping of polycrystalline structure of histological sections of biological tissues is suggested. The algorithms of reconstruction of distribution of parameters of linear and circular birefringence of prostate histological sections are found. The interconnections between such distributions and parameters of linear and circular birefringence of prostate tissue histological sections are defined. The comparative investigations of coordinate distributions of phase anisotropy parameters formed by fibrillar networks of prostate tissues of different pathological states (adenoma and carcinoma) are performed. The values and ranges of change of the statistical (moments of the 1st - 4th order) parameters of coordinate distributions of the value of linear and circular birefringence are defined. The objective criteria of cause of Benign and malignant conditions differentiation are determined.

Interaction of a penny-shaped crack and an external circular crack in a transversely isotropic composite

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tsai, Y.M.

1998-12-31

The interaction of a penny-shaped crack and an external circular crack in a transversely isotropic composite is investigated using the techniques of Hankel transform and multiplying factors. The boundary conditions of the problem have three different parts. The stress intensity factors at the inner and the outer crack tips are obtained in exact expressions as the products of a dimensional quantity and nondimensional functions. The presence of a penny-shaped crack is shown to have a strong effect on the magnitude of the stress intensity of the external circular crack. The crack surface displacement is also obtained and evaluated numerically formore » different values of the ratio of the inner crack radius to the external crack radius.« less

Generalized serial search code acquisition - The equivalent circular state diagram approach

NASA Technical Reports Server (NTRS)

Polydoros, A.; Simon, M. K.

1984-01-01

A transform-domain method for deriving the generating function of the acquisition process resulting from an arbitrary serial search strategy is presented. The method relies on equivalent circular state diagrams, uses Mason's formula from flow-graph theory, and employs a minimum number of required parameters. The transform-domain approach is briefly described and the concept of equivalent circular state diagrams is introduced and exploited to derive the generating function and resulting mean acquisition time for three particular cases of interest, the continuous/center Z search, the broken/center Z search, and the expanding window search. An optimization of the latter technique is performed whereby the number of partial windows which minimizes the mean acquisition time is determined. The numerical results satisfy certain intuitive predictions and provide useful design guidelines for such systems.

Circularly polarized light to study linear magneto-optics for ferrofluids: θ-scan technique

NASA Astrophysics Data System (ADS)

Meng, Xiangshen; Huang, Yan; He, Zhenghong; Lin, Yueqiang; Liu, Xiaodong; Li, Decai; Li, Jian; Qiu, Xiaoyan

2018-06-01

Circularly polarized light can be divided into two vertically linearly polarized light beams with  ±π/2 phase differences. In the presence of an external magnetic field, when circularly polarized light travels through a ferrofluid film, whose thickness is no more than that of λ/4 plate, magneto-optical, magnetic birefringence and dichroism effects cause the transmitted light to behave as elliptically polarized light. Using angular scan by a continuously rotating polarizer as analyzer, the angular (θ) distribution curve of relative intensity (T) corresponding to elliptically polarized light can be measured. From the T  ‑  θ curve having ellipsometry, the parameters such as the ratio of short to long axis, and angular orientation of the long axis to the vertical field direction can be obtained. Thus, magnetic birefringence and dichroism can be probed simultaneously by measuring magneto-optical, positive or negative birefringence and dichroism features from the transmission mode. The proposed method is called θ-scan technique, and can accurately determine sample stability, magnetic field direction, and cancel intrinsic light source ellipticity. This study may be helpful to further research done to ferrofluids and other similar colloidal samples with anisotropic optics.

High-Power Rf Load

DOEpatents

Tantawi, Sami G.; Vlieks, Arnold E.

1998-09-01

A compact high-power RF load comprises a series of very low Q resonators, or chokes [16], in a circular waveguide [10]. The sequence of chokes absorb the RF power gradually in a short distance while keeping the bandwidth relatively wide. A polarizer [12] at the input end of the load is provided to convert incoming TE.sub.10 mode signals to circularly polarized TE.sub.11 mode signals. Because the load operates in the circularly polarized mode, the energy is uniformly and efficiently absorbed and the load is more compact than a rectangular load. Using these techniques, a load having a bandwidth of 500 MHz can be produced with an average power dissipation level of 1.5 kW at X-band, and a peak power dissipation of 100 MW. The load can be made from common lossy materials, such as stainless steel, and is less than 15 cm in length. These techniques can also produce loads for use as an alternative to ordinary waveguide loads in small and medium RF accelerators, in radar systems, and in other microwave applications. The design is easily scalable to other RF frequencies and adaptable to the use of other lossy materials.

Elucidating the interaction of clofazimine with bovine liver catalase; a comprehensive spectroscopic and molecular docking approach.

PubMed

Zaman, Masihuz; Nusrat, Saima; Zakariya, Syed Mohammad; Khan, Mohsin Vahid; Ajmal, Mohammad Rehan; Khan, Rizwan Hasan

2017-08-01

Nowadays, understanding of interface between protein and drugs has become an active research area of interest. These types of interactions provide structural guidelines in drug design with greater clinical efficacy. Thus, structural changes in catalase induced by clofazimine were monitored by various biophysical techniques including UV-visible spectrometer, fluorescence spectroscopy, circular dichroism, and dynamic light scattering techniques. Increase in absorption spectra (UV-visible spectrum) confers the complex formation between drug and protein. Fluorescence quenching with a binding constants of 2.47 × 10 4  M -1 revealed that clofazimine binds with protein. Using fluorescence resonance energy transfer, the distance (r) between the protein (donor) and drug (acceptor) was found to be 2.89 nm. Negative Gibbs free energy change (ΔG°) revealed that binding process is spontaneous. In addition, an increase in α-helicity was observed by far-UV circular dichroism spectra by adding clofazimine to protein. Dynamic light scattering results indicate that topology of bovine liver catalase was slightly altered in the presence of clofazimine. Hydrophobic interactions are the main forces between clofazimine and catalase interaction as depicted by molecular docking studies. Apart from hydrophobic interactions, some hydrogen bonding was also observed during docking method. The results obtained from the present study may establish abundant in optimizing the properties of ligand-protein mixtures relevant for numerous formulations. Copyright © 2017 John Wiley & Sons, Ltd.

Weighted least squares techniques for improved received signal strength based localization.

PubMed

Tarrío, Paula; Bernardos, Ana M; Casar, José R

2011-01-01

The practical deployment of wireless positioning systems requires minimizing the calibration procedures while improving the location estimation accuracy. Received Signal Strength localization techniques using propagation channel models are the simplest alternative, but they are usually designed under the assumption that the radio propagation model is to be perfectly characterized a priori. In practice, this assumption does not hold and the localization results are affected by the inaccuracies of the theoretical, roughly calibrated or just imperfect channel models used to compute location. In this paper, we propose the use of weighted multilateration techniques to gain robustness with respect to these inaccuracies, reducing the dependency of having an optimal channel model. In particular, we propose two weighted least squares techniques based on the standard hyperbolic and circular positioning algorithms that specifically consider the accuracies of the different measurements to obtain a better estimation of the position. These techniques are compared to the standard hyperbolic and circular positioning techniques through both numerical simulations and an exhaustive set of real experiments on different types of wireless networks (a wireless sensor network, a WiFi network and a Bluetooth network). The algorithms not only produce better localization results with a very limited overhead in terms of computational cost but also achieve a greater robustness to inaccuracies in channel modeling.

Weighted Least Squares Techniques for Improved Received Signal Strength Based Localization

PubMed Central

Tarrío, Paula; Bernardos, Ana M.; Casar, José R.

2011-01-01

The practical deployment of wireless positioning systems requires minimizing the calibration procedures while improving the location estimation accuracy. Received Signal Strength localization techniques using propagation channel models are the simplest alternative, but they are usually designed under the assumption that the radio propagation model is to be perfectly characterized a priori. In practice, this assumption does not hold and the localization results are affected by the inaccuracies of the theoretical, roughly calibrated or just imperfect channel models used to compute location. In this paper, we propose the use of weighted multilateration techniques to gain robustness with respect to these inaccuracies, reducing the dependency of having an optimal channel model. In particular, we propose two weighted least squares techniques based on the standard hyperbolic and circular positioning algorithms that specifically consider the accuracies of the different measurements to obtain a better estimation of the position. These techniques are compared to the standard hyperbolic and circular positioning techniques through both numerical simulations and an exhaustive set of real experiments on different types of wireless networks (a wireless sensor network, a WiFi network and a Bluetooth network). The algorithms not only produce better localization results with a very limited overhead in terms of computational cost but also achieve a greater robustness to inaccuracies in channel modeling. PMID:22164092

Optimized fan-shaped chiral metamaterial as an ultrathin narrow-band circular polarizer at visible frequencies

NASA Astrophysics Data System (ADS)

He, Yizhuo; Wang, Xinghai; Ingram, Whitney; Ai, Bin; Zhao, Yiping

2018-04-01

Chiral metamaterials have the great ability to manipulate the circular polarizations of light, which can be utilized to build ultrathin circular polarizers. Here we build a narrow-band circular polarizer at visible frequencies based on plasmonic fan-shaped chiral nanostructures. In order to achieve the best optical performance, we systematically investigate how different fabrication factors affect the chiral optical response of the fan-shaped chiral nanostructures, including incident angle of vapor depositions, nanostructure thickness, and post-deposition annealing. The optimized fan-shaped nanostructures show two narrow bands for different circular polarizations with the maximum extinction ratios 7.5 and 6.9 located at wavelength 687 nm and 774 nm, respectively.

A safe and reproducible anastomotic technique for minimally invasive Ivor Lewis oesophagectomy: the circular-stapled anastomosis with the trans-oral anvil.

PubMed

Campos, Guilherme M; Jablons, David; Brown, Lisa M; Ramirez, René M; Rabl, Charlotte; Theodore, Pierre

2010-06-01

In expert hands, the intrathoracic oesophago-gastric anastamosis usually provides a low rate of strictures and leaks. However, anastomoses can be technically challenging and time consuming when minimally invasive techniques are used. We present our preliminary results of a standardised 25 mm/4.8mm circular-stapled anastomosis using a trans-orally placed anvil. We evaluated a prospective cohort of 37 consecutive patients offered minimally invasive Ivor Lewis oesophagectomy at a tertiary referral centre. The oesophago-gastric anastomosis was created using a 25-mm anvil (Orvil, Autosuture, Norwalk, CT, USA) passed trans-orally, in a tilted position, and connected to a 90-cm long polyvinyl chloride delivery tube through an opening in the oesophageal stump. The anastomosis was completed by joining the anvil to a circular stapler (end-to-end anastomosis stapler (EEA XL) 25 mm with 4.8-mm staples, Autosuture, Norwalk, CT, USA) inserted into the gastric conduit. Primary outcomes were leak and stricture rates. Thirty-seven patients (mean age 65 years) with distal oesophageal adenocarcinoma (n=29), squamous cell cancer (n=5) or high-grade dysplasia in Barrett's oesophagus (n=3) underwent an Ivor Lewis oesophagectomy between October 2007 and August 2009. The abdominal portion was operated laparoscopically in 30 patients (81.1%). The thoracic portion was done using a muscle-sparing mini-thoracotomy in 23 patients (62.2%) and thoracoscopic techniques in 14 patients (37.8%). There were no intra-operative technical failures of the anastomosis or deaths. Five patients had strictures (13.5%) and all were successfully treated with endoscopic dilations. One patient had an anastomotic leak (2.7%) that was successfully treated by re-operation and endoscopic stenting of the anastomosis. The circular-stapled anastomosis with the trans-oral anvil allows for an efficient, safe and reproducible anastomosis. This straightforward technique is particularly suited to the completely minimally invasive Ivor Lewis oesophagectomy. Copyright 2010 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.

Etude de solutions pour la mise en oeuvre d'une antenne a reflecteur bi-grille en polarisation circulaire

NASA Astrophysics Data System (ADS)

Joyal, Marc-Andre

Dual-gridded reflector (DGR) antennas are widely used on satellites. They consist of a cascade of two parabolic grids operating in orthogonal linear polarizations, each one having its own feed. Therefore, DGRs are actually two antennas in one structure, so they use less space on the satellite. Moreover, they provide excellent isolation between adjacent coverage areas. The disadvantage with these DGRs is that they work only in linear polarization (vertical and horizontal). In this thesis, two different solutions to design a circularly polarized (right and left hand circular polarizations) DGR are explored. The first one consists in the use of circular polarizers that are fixed on a conventional DGR. Those polarizers are surfaces that make the conversion between linear and circular polarizations. The other solution uses circular polarization selective surfaces (CPSSs) as reflectors on the DGR instead of the orthogonal grids. These CPSSs are structures that are transparent to one sense of circular polarization (say right hand circular polarization for instance), but that reflect the other sense (left hand circular polarization). The major part of this work is based on the first solution. A new circular polarizer design method is proposed. It allows a greater flexibility in the polarizer design than existing designs. The proposed technique is also modified in order to implement polarizers optimized for an oblique incidence, which is required for DGR applications. The second solution using CPSSs is only briefly explored. A new type of CPSS, implemented with a cascade of circular and linear polarizers, is proposed. This cascade CPSS has shown a broader bandwidth than those obtained with the resonant structures known so far. Also, the limitations of CPSSs are identified as to their use on DGRs. Finally, as a proof of concept, two simple prototypes of circularly polarized DGRs are presented. The first design is implemented with a circular polarizer and a metallic grid attached to a small reflector. The second prototype is similar, but the planar grid is replaced by a reflectarray that plays the same role, but increases the gain in the direction of the main beam. The satellite industry requirements between 18-20 GHz are respected with this latter implementation, but only for a very low variation in the elevation angle.

Design and fabrication of microstrip antenna arrays

NASA Technical Reports Server (NTRS)

1978-01-01

A microstrip array project was conducted to demonstrate the feasibility of designing and fabricating simple, low cost, low sidelobe phased arrays with circular disk microstrip radiating elements. Design data were presented for microstrip elements and arrays including the effects of the protective covers, the mutual interaction between elements, and stripline feed network design. Low cost multilayer laminate fabrication techniques were also investigated. Utilizing this design data two C-band low sidelobe arrays were fabricated and tested: an eight-element linear and a sixty-four element planar array. These arrays incorporated stripline Butler matrix feed networks to produce a low sidelobe broadside beam.

Combinatorial control of Drosophila circular RNA expression by intronic repeats, hnRNPs, and SR proteins.

PubMed

Kramer, Marianne C; Liang, Dongming; Tatomer, Deirdre C; Gold, Beth; March, Zachary M; Cherry, Sara; Wilusz, Jeremy E

2015-10-15

Thousands of eukaryotic protein-coding genes are noncanonically spliced to produce circular RNAs. Bioinformatics has indicated that long introns generally flank exons that circularize in Drosophila, but the underlying mechanisms by which these circular RNAs are generated are largely unknown. Here, using extensive mutagenesis of expression plasmids and RNAi screening, we reveal that circularization of the Drosophila laccase2 gene is regulated by both intronic repeats and trans-acting splicing factors. Analogous to what has been observed in humans and mice, base-pairing between highly complementary transposable elements facilitates backsplicing. Long flanking repeats (∼ 400 nucleotides [nt]) promote circularization cotranscriptionally, whereas pre-mRNAs containing minimal repeats (<40 nt) generate circular RNAs predominately after 3' end processing. Unlike the previously characterized Muscleblind (Mbl) circular RNA, which requires the Mbl protein for its biogenesis, we found that Laccase2 circular RNA levels are not controlled by Mbl or the Laccase2 gene product but rather by multiple hnRNP (heterogeneous nuclear ribonucleoprotein) and SR (serine-arginine) proteins acting in a combinatorial manner. hnRNP and SR proteins also regulate the expression of other Drosophila circular RNAs, including Plexin A (PlexA), suggesting a common strategy for regulating backsplicing. Furthermore, the laccase2 flanking introns support efficient circularization of diverse exons in Drosophila and human cells, providing a new tool for exploring the functional consequences of circular RNA expression across eukaryotes. © 2015 Kramer et al.; Published by Cold Spring Harbor Laboratory Press.

Room temperature high circular dichroism ultraviolet lasing from planar spiral metal-GaN nanowire cavity (Conference Presentation)

NASA Astrophysics Data System (ADS)

Shih, Min-Hsiung

2016-09-01

Circularly polarized light and chiroptical effect have received considerable attention in advanced photonic and electronic technologies including optical spintronics, quantum-based optical information processing and communication, and high-efficiency liquid crystal display backlights. Moreover, the development of circularly polarized photon sources has played a major role in circular dichroism (CD) spectroscopy, which is important for analyses of optically active molecules, chiral synthesis in biology and chemistry, and ultrafast magnetization control. However, the conventional collocation of light-emitting devices and additional circular-polarization converters that produce circularly polarized beams makes the setup bulky and hardly compatible with nanophotonic devices in ultrasmall scales. In fact, the direct generation of circularly polarized photons may simplify the system integration, compact the setup, lower the cost of external components, and perhaps enhance the power efficiency. In this work, with the spiral-type metal-gallium nitride (GaN) nanowire cavity, we demonstrated an ultrasmall semiconductor laser capable of emitting circularly-polarized photons. The left- and right-hand spiral metal nanowire cavities with varied periods were designed at ultraviolet wavelengths to achieve the high quality factor circular dichroism metastructures. The dissymmetry factors characterizing the degrees of circular polarizations of the left- and right-hand chiral lasers were 1.4 and -1.6 (2 if perfectly circular polarized), respectively. The results show that the chiral cavities with only 5 spiral periods can achieve lasing signals with decently high degrees of circular polarizations.

Imaging photoelectron circular dichroism of chiral molecules by femtosecond multiphoton coincidence detection.

PubMed

Lehmann, C Stefan; Ram, N Bhargava; Powis, Ivan; Janssen, Maurice H M

2013-12-21

Here, we provide a detailed account of novel experiments employing electron-ion coincidence imaging to discriminate chiral molecules. The full three-dimensional angular scattering distribution of electrons is measured after photoexcitation with either left or right circular polarized light. The experiment is performed using a simplified photoelectron-photoion coincidence imaging setup employing only a single particle imaging detector. Results are reported applying this technique to enantiomers of the chiral molecule camphor after three-photon ionization by circularly polarized femtosecond laser pulses at 400 nm and 380 nm. The electron-ion coincidence imaging provides the photoelectron spectrum of mass-selected ions that are observed in the time-of-flight mass spectra. The coincident photoelectron spectra of the parent camphor ion and the various fragment ions are the same, so it can be concluded that fragmentation of camphor happens after ionization. We discuss the forward-backward asymmetry in the photoelectron angular distribution which is expressed in Legendre polynomials with moments up to order six. Furthermore, we present a method, similar to one-photon electron circular dichroism, to quantify the strength of the chiral electron asymmetry in a single parameter. The circular dichroism in the photoelectron angular distribution of camphor is measured to be 8% at 400 nm. The electron circular dichroism using femtosecond multiphoton excitation is of opposite sign and about 60% larger than the electron dichroism observed before in near-threshold one-photon ionization with synchrotron excitation. We interpret our multiphoton ionization as being resonant at the two-photon level with the 3s and 3p Rydberg states of camphor. Theoretical calculations are presented that model the photoelectron angular distribution from a prealigned camphor molecule using density functional theory and continuum multiple scattering X alpha photoelectron scattering calculations. Qualitative agreement is observed between the experimental results and the theoretical calculations of the Legendre moments representing the angular distribution for the two enantiomers. The electron-ion coincidence technique using multiphoton ionization opens new directions in table-top analytical mass-spectrometric applications of mixtures of chiral molecules.

Imaging photoelectron circular dichroism of chiral molecules by femtosecond multiphoton coincidence detection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lehmann, C. Stefan; Ram, N. Bhargava; Janssen, Maurice H. M., E-mail: m.h.m.janssen@vu.nl

2013-12-21

Here, we provide a detailed account of novel experiments employing electron-ion coincidence imaging to discriminate chiral molecules. The full three-dimensional angular scattering distribution of electrons is measured after photoexcitation with either left or right circular polarized light. The experiment is performed using a simplified photoelectron-photoion coincidence imaging setup employing only a single particle imaging detector. Results are reported applying this technique to enantiomers of the chiral molecule camphor after three-photon ionization by circularly polarized femtosecond laser pulses at 400 nm and 380 nm. The electron-ion coincidence imaging provides the photoelectron spectrum of mass-selected ions that are observed in the time-of-flightmore » mass spectra. The coincident photoelectron spectra of the parent camphor ion and the various fragment ions are the same, so it can be concluded that fragmentation of camphor happens after ionization. We discuss the forward-backward asymmetry in the photoelectron angular distribution which is expressed in Legendre polynomials with moments up to order six. Furthermore, we present a method, similar to one-photon electron circular dichroism, to quantify the strength of the chiral electron asymmetry in a single parameter. The circular dichroism in the photoelectron angular distribution of camphor is measured to be 8% at 400 nm. The electron circular dichroism using femtosecond multiphoton excitation is of opposite sign and about 60% larger than the electron dichroism observed before in near-threshold one-photon ionization with synchrotron excitation. We interpret our multiphoton ionization as being resonant at the two-photon level with the 3s and 3p Rydberg states of camphor. Theoretical calculations are presented that model the photoelectron angular distribution from a prealigned camphor molecule using density functional theory and continuum multiple scattering X alpha photoelectron scattering calculations. Qualitative agreement is observed between the experimental results and the theoretical calculations of the Legendre moments representing the angular distribution for the two enantiomers. The electron-ion coincidence technique using multiphoton ionization opens new directions in table-top analytical mass-spectrometric applications of mixtures of chiral molecules.« less

Steady viscous flow past a circular cylinder

NASA Technical Reports Server (NTRS)

Fornberg, B.

1984-01-01

Viscous flow past a circular cylinder becomes unstable around Reynolds number Re = 40. With a numerical technique based on Newton's method and made possible by the use of a supercomputer, steady (but unstable) solutions have been calculated up to Re = 400. It is found that the wake continues to grow in length approximately linearly with Re. However, in conflict with available asymptotic predictions, the width starts to increase very rapidly around Re = 300. All numerical calculations have been performed on the CDC CYBER 205 at the CDC Service Center in Arden Hills, Minnesota.

Radio Emission from Algol. I. Coronal Geometry and Emission Mechanisms Determined from VLBA and Green Bank Interferometer Observations

NASA Astrophysics Data System (ADS)

Mutel, R. L.; Molnar, L. A.; Waltman, E. B.; Ghigo, F. D.

1998-11-01

We report dual circular polarization VLBA observations of Algol made at orbital phases 0.22-0.30 using a differential phase referencing technique. The flux density of Algol varied from 10 to 20 mJy during the observations. The radio maps show a double-lobed source separated by 1.6 mas (1.4 times the K star diameter). Although the total emission is only weakly circularly polarized, the individual lobes are strongly circularly polarized and of opposite helicity. Snapshot VLBI maps made at 3 hour intervals show variations in the flux density of both components, but no significant motions of the centroids. We also analyze Green Bank Interferometer (GBI) synoptic observations of right- and left-circularly polarized (RCP and LCP) flux densities of Algol at 2.3 and 8.3 GHz several times a day from early 1995 to mid-1997. The resulting data set, which consists of more than 2500 observations over 2 years, is by far the most comprehensive available for any stellar system. In addition, we analyzed GBI observations of the very similar (but noneclipsing) binary system HR 1099 over the same time period in order to compare the two systems. We summarize the GBI observations using several statistical descriptions. We find no phase dependence of either the radio luminosity or circular polarization for either system. The luminosity histograms for the two systems are remarkably similar. The distribution functions are not well represented by exponentials as previously suggested, but can be represented by power laws truncated at low luminosity. The cutoff occurs at 20-30 mJy and may represent emission from a slowly varying basal level that is always detected. We confirm several previous results, including the strong dependence of spectral index on luminosity, the decrease of fractional circular polarization with luminosity, and the dependence of fractional circular polarization on orbital inclination angle. We suggest that the radio emission at 8.3 GHz is x-mode gyrosynchrotron emission from optically thin emission regions containing mildly relativistic electrons in a dipolar magnetic field. There is no evidence for highly circularly polarized coherent flares at 8.3 GHz, although it is possible that such flares occasionally occur at 2.25 GHz. The lack of orbital phase dependence in the GBI light curves, combined with the significant inclination of the VLBA structure with respect to the orbital plane, is inconsistent with previous models in which the radio lobes are located in the equatorial plane. The individual lobes seen in the VLBI maps may be associated with the polar regions, with the strong circular polarization resulting from the opposed mean magnetic field vector component along the observer's line of sight in opposite hemispheres. Astrometric results from the VLBA observations are discussed in a companion paper.

Circular polarization of light by planet Mercury and enantiomorphism of its surface minerals.

PubMed

Meierhenrich, Uwe J; Thiemann, Wolfram H P; Barbier, Bernard; Brack, André; Alcaraz, Christian; Nahon, Laurent; Wolstencroft, Ray

2002-04-01

Different mechanisms for the generation of circular polarization by the surface of planets and satellites are described. The observed values for Venus, the Moon, Mars, and Jupiter obtained by photo-polarimetric measurements with Earth based telescopes, showed accordance with theory. However, for planet Mercury asymmetric parameters in the circular polarization were measured that do not fit with calculations. For BepiColombo, the ESA cornerstone mission 5 to Mercury, we propose to investigate this phenomenon using a concept which includes two instruments. The first instrument is a high-resolution optical polarimeter, capable to determine and map the circular polarization by remote scanning of Mercury's surface from the Mercury Planetary Orbiter MPO. The second instrument is an in situ sensor for the detection of the enantiomorphism of surface crystals and minerals, proposed to be included in the Mercury Lander MSE.

Geologic analysis and evaluation of ERTS-A imagery for the State of New Mexico

NASA Technical Reports Server (NTRS)

Kottlowski, F. E. (Principal Investigator)

1974-01-01

The author has identified the following significant results. Many circular to elliptical features have been identified on the ERTS-1 images, only some of which can be accounted for by existing data. A small number of circular features are adjacent to existing ore deposits, but such relationships should not be emphasized unless other supporting data exists. Circular features may be tectonically or geomorphically controlled, or a combination of the two. A limited number are man-made. A preliminary listing of features which may have circular expression are listed. Photographic examples of identified and unidentified circular features will be included in the final report along with a thorough discussion and analysis. Comparisons will be made with existing gravity and magnetic data.

The Effect of the π-Electron Delocalization Curvature on the Two-Photon Circular Dichroism of Molecules with Axial Chirality.

PubMed

Diaz, Carlos; Lin, Na; Toro, Carlos; Passier, Remy; Rizzo, Antonio; Hernández, Florencio E

2012-07-05

Herein we report on the theoretical-experimental study of the effect of curvature of the π-electron delocalization on the two-photon circular dichroism (TPCD) of a family of optically active biaryl derivatives (S-BINOL, S-VANOL, and S-VAPOL). The comparative analysis of the influence of the different transition moments to their corresponding TPCD rotatory strength reveals an enhanced contribution of the magnetic transition dipole moment on VAPOL. This effect is hereby attributed to the additional twist in the π-electron delocalization on this compound. TPCD measurements were done using the double L-scan technique in the picosecond regime. Theoretical calculations were completed using modern analytical response theory, within a time-dependent density functional theory (TD-DFT) approach, at both, B3LYP and CAM-B3LYP levels, with the aug-cc-pVDZ basis set for S-BINOL and S-VANOL, and 6-31G* for S-VAPOL. Solvent effects were included by means of the polarizable continuum model (PCM) in CH2Cl2.

Intrinsic Optical Activity and Environmental Perturbations: Solvation Effects in Chiral Building Blocks

NASA Astrophysics Data System (ADS)

Lemler, Paul M.; Vaccaro, Patrick

2016-06-01

The non-resonant interaction of electromagnetic radiation with an isotropic ensemble of chiral molecules, which causes the incident state of linear polarization to undergo a signed rotation, long has served as a metric for gauging the enantiomeric purity of asymmetric syntheses. While the underlying phenomenon of circular birefringence (CB) typically is probed in the condensed phase, recent advances in ultrasensitive circular-differential detection schemes, as exemplified by the techniques of Cavity Ring-Down Polarimetry (CRDP), have permitted the first quantitative analyses of such processes to be performed in rarefied media. Efforts to extend vapor-phase investigations of CB to new families of chiral substrates will be discussed, with particular emphasis directed towards the elucidation of intrinsic (e.g., solvent-free) properties and their mediation by environmental perturbations (e.g., solvation). Specific species targeted by this work will include the stereoselective building blocks phenylpropylene oxide and α-methylbenzyl amine, both of which exhibit pronounced solvent-dependent changes in measured optical activity. The nature of chiroptical response in different environments will be highlighted, with quantum-chemical calculations serving to unravel the structural and electronic provenance of observed behavior.

Wind-driven currents in a shallow lake or sea

NASA Technical Reports Server (NTRS)

Goldstein, M. E.; Gedney, R. T.

1971-01-01

For shallow lakes and seas such as the great lakes (especially Lake Erie) where the depth is not much greater than the Ekman depth, the usual Ekman dynamics cannot be used to predict the wind driven currents. The necessary extension to include shallow bodies of water, given by Welander, leads to a partial differential equation for the surface displacement which in turn determines all other flow quantities. A technique for obtaining exact analytical solutions to Welander's equation for bodies of water with large class of bottom topographies which may or may not contain islands is given. It involves applying conformal mapping methods to an extension of Welander's equation into the complex plane. When the wind stress is constant (which is the usual assumption for lakes) the method leads to general solutions which hold for bodies of water of arbitrary shape (the shape appears in the solutions through a set of constants which are the coefficients in the Laurent expansion of a mapping of the particular lake geometry). The method is applied to an elliptically shaped lake and a circular lake containing an eccentrically located circular island.

Numerical Solution of the Flow of a Perfect Gas Over A Circular Cylinder at Infinite Mach Number

NASA Technical Reports Server (NTRS)

Hamaker, Frank M.

1959-01-01

A solution for the two-dimensional flow of an inviscid perfect gas over a circular cylinder at infinite Mach number is obtained by numerical methods of analysis. Nonisentropic conditions of curved shock waves and vorticity are included in the solution. The analysis is divided into two distinct regions, the subsonic region which is analyzed by the relaxation method of Southwell and the supersonic region which was treated by the method of characteristics. Both these methods of analysis are inapplicable on the sonic line which is therefore considered separately. The shapes of the sonic line and the shock wave are obtained by iteration techniques. The striking result of the solution is the strong curvature of the sonic line and of the other lines of constant Mach number. Because of this the influence of the supersonic flow on the sonic line is negligible. On comparison with Newtonian flow methods, it is found that the approximate methods show a larger variation of surface pressure than is given by the present solution.

Circular RNAs: diversity of form and function.

PubMed

Lasda, Erika; Parker, Roy

2014-12-01

It is now clear that there is a diversity of circular RNAs in biological systems. Circular RNAs can be produced by the direct ligation of 5' and 3' ends of linear RNAs, as intermediates in RNA processing reactions, or by "backsplicing," wherein a downstream 5' splice site (splice donor) is joined to an upstream 3' splice site (splice acceptor). Circular RNAs have unique properties including the potential for rolling circle amplification of RNA, the ability to rearrange the order of genomic information, protection from exonucleases, and constraints on RNA folding. Circular RNAs can function as templates for viroid and viral replication, as intermediates in RNA processing reactions, as regulators of transcription in cis, as snoRNAs, and as miRNA sponges. Herein, we review the breadth of circular RNAs, their biogenesis and metabolism, and their known and anticipated functions. © 2014 Lasda and Parker; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

Circular RNAs: diversity of form and function

PubMed Central

Lasda, Erika

2014-01-01

It is now clear that there is a diversity of circular RNAs in biological systems. Circular RNAs can be produced by the direct ligation of 5′ and 3′ ends of linear RNAs, as intermediates in RNA processing reactions, or by “backsplicing,” wherein a downstream 5′ splice site (splice donor) is joined to an upstream 3′ splice site (splice acceptor). Circular RNAs have unique properties including the potential for rolling circle amplification of RNA, the ability to rearrange the order of genomic information, protection from exonucleases, and constraints on RNA folding. Circular RNAs can function as templates for viroid and viral replication, as intermediates in RNA processing reactions, as regulators of transcription in cis, as snoRNAs, and as miRNA sponges. Herein, we review the breadth of circular RNAs, their biogenesis and metabolism, and their known and anticipated functions. PMID:25404635

Application of wave mechanics theory to fluid dynamics problems: Boundary layer on a circular cylinder including turbulence

NASA Technical Reports Server (NTRS)

Krzywoblocki, M. Z. V.

1974-01-01

The application of the elements of quantum (wave) mechanics to some special problems in the field of macroscopic fluid dynamics is discussed. Emphasis is placed on the flow of a viscous, incompressible fluid around a circular cylinder. The following subjects are considered: (1) the flow of a nonviscous fluid around a circular cylinder, (2) the restrictions imposed the stream function by the number of dimensions of space, and (3) the flow past three dimensional bodies in a viscous fluid, particularly past a circular cylinder in the symmetrical case.

76 FR 70037 - Federal Regulations; OMB Circulars, OFPP Policy Letters, and CASB Cost Accounting Standards...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-10

... Circulars, OFPP Policy Letters, and CASB Cost Accounting Standards Included in the Semiannual Agenda of..., and Cost Accounting Standards Board (CASB) Cost Accounting Standards. DATES: The withdrawal is...

Temperature field determination in slabs, circular plates and spheres with saw tooth heat generating sources

NASA Astrophysics Data System (ADS)

Diestra Cruz, Heberth Alexander

The Green's functions integral technique is used to determine the conduction heat transfer temperature field in flat plates, circular plates, and solid spheres with saw tooth heat generating sources. In all cases the boundary temperature is specified (Dirichlet's condition) and the thermal conductivity is constant. The method of images is used to find the Green's function in infinite solids, semi-infinite solids, infinite quadrants, circular plates, and solid spheres. The saw tooth heat generation source has been modeled using Dirac delta function and Heaviside step function. The use of Green's functions allows obtain the temperature distribution in the form of an integral that avoids the convergence problems of infinite series. For the infinite solid and the sphere, the temperature distribution is three-dimensional and in the cases of semi-infinite solid, infinite quadrant and circular plate the distribution is two-dimensional. The method used in this work is superior to other methods because it obtains elegant analytical or quasi-analytical solutions to complex heat conduction problems with less computational effort and more accuracy than the use of fully numerical methods.

Experimental investigation of the effect of Reynolds number on flow structures in the wake of a circular parachute canopy

NASA Astrophysics Data System (ADS)

Jin, Zhe-Yan; Pasqualini, Sylvio; Qin, Bo

2014-06-01

In the present study, an experimental study was conducted to characterize the effect of Reynolds number on flow structures in the turbulent wake of a circular parachute canopy by utilizing stereoscopic particle image velocimetry (Stereo-PIV) technique. The parachute model tested in the present study was attached by 28 nylon suspension lines and placed horizontally at the test section center of the wind tunnel. The obtained results showed that with the increase of Reynolds number, the intensities of the vortices near the downstream region of the canopy skirt were found to increase accordingly. However, the increase of Reynolds number did not result in a significant change in ensembleaveraged normalized x-component of the velocity, ensembleaveraged normalized vorticity, normalized Reynolds stress, and normalized turbulent kinetic energy distributions in the turbulent wake of the circular parachute canopy. The obtained results are very useful to further our understanding about the unsteady aerodynamics in the wake of flexible circular parachute canopies and to constitute a reference for CFD computation.

Inductive coupler for downhole components and method for making same

DOEpatents

Hall, David R.; Hall, Jr., H. Tracy; Pixton, David S.; Dahlgren, Scott; Briscoe, Michael A.; Sneddon, Cameron; Fox, Joe

2006-05-09

The present invention includes a method of making an inductive coupler for downhole components. The method includes providing an annular housing, preferably made of steel, the housing having a recess. A conductor, preferably an insulated wire, is also provided along with a plurality of generally U-shaped magnetically conducting, electrically insulating (MCEI) segments. Preferably, the MCEI segments comprise ferrite. An assembly is formed by placing the plurality of MCEI segments within the recess in the annular housing. The segments are aligned to form a generally circular trough. A first portion of the conductor is placed within the circular trough. This assembly is consolidated with a meltable polymer which fills spaces between the segments, annular housing and the first portion of the conductor. The invention also includes an inductive coupler including an annular housing having a recess defined by a bottom portion and two opposing side wall portions. At least one side wall portion includes a lip extending toward but not reaching the other side wall portion. A plurality of generally U-shaped MCEI segments, preferably comprised of ferrite, are disposed in the recess and aligned so as to form a circular trough. The coupler further includes a conductor disposed within the circular trough and a polymer filling spaces between the segments, the annular housing and the conductor.

Identification of Circular RNAs from the Parental Genes Involved in Multiple Aspects of Cellular Metabolism in Barley

PubMed Central

Darbani, Behrooz; Noeparvar, Shahin; Borg, Søren

2016-01-01

RNA circularization made by head-to-tail back-splicing events is involved in the regulation of gene expression from transcriptional to post-translational levels. By exploiting RNA-Seq data and down-stream analysis, we shed light on the importance of circular RNAs in plants. The results introduce circular RNAs as novel interactors in the regulation of gene expression in plants and imply the comprehensiveness of this regulatory pathway by identifying circular RNAs for a diverse set of genes. These genes are involved in several aspects of cellular metabolism as hormonal signaling, intracellular protein sorting, carbohydrate metabolism and cell-wall biogenesis, respiration, amino acid biosynthesis, transcription and translation, and protein ubiquitination. Additionally, these parental loci of circular RNAs, from both nuclear and mitochondrial genomes, encode for different transcript classes including protein coding transcripts, microRNA, rRNA, and long non-coding/microprotein coding RNAs. The results shed light on the mitochondrial exonic circular RNAs and imply the importance of circular RNAs for regulation of mitochondrial genes. Importantly, we introduce circular RNAs in barley and elucidate their cellular-level alterations across tissues and in response to micronutrients iron and zinc. In further support of circular RNAs' functional roles in plants, we report several cases where fluctuations of circRNAs do not correlate with the levels of their parental-loci encoded linear transcripts. PMID:27375638

Systems and Methods for Implementing Bulk Metallic Glass-Based Strain Wave Gears and Strain Wave Gear Components

NASA Technical Reports Server (NTRS)

Hofmann, Douglas C. (Inventor); Wilcox, Brian (Inventor)

2016-01-01

Bulk metallic glass-based strain wave gears and strain wave gear components. In one embodiment, a strain wave gear includes: a wave generator; a flexspline that itself includes a first set of gear teeth; and a circular spline that itself includes a second set of gear teeth; where at least one of the wave generator, the flexspline, and the circular spline, includes a bulk metallic glass-based material.

Circular dichroism spectroscopy: Enhancing a traditional undergraduate biochemistry laboratory experience.

PubMed

Lewis, Russell L; Seal, Erin L; Lorts, Aimee R; Stewart, Amanda L

2017-11-01

The undergraduate biochemistry laboratory curriculum is designed to provide students with experience in protein isolation and purification protocols as well as various data analysis techniques, which enhance the biochemistry lecture course and give students a broad range of tools upon which to build in graduate level laboratories or once they begin their careers. One of the most common biochemistry protein purification experiments is the isolation and characterization of cytochrome c. Students across the country purify cytochrome c, lysozyme, or some other well-known protein to learn these common purification techniques. What this series of experiments lacks is the use of sophisticated instrumentation that is rarely available to undergraduate students. To give students a broader background in biochemical spectroscopy techniques, a new circular dichroism (CD) laboratory experiment was introduced into the biochemistry laboratory curriculum. This CD experiment provides students with a means of conceptualizing the secondary structure of their purified protein, and assessments indicate that students' understanding of the technique increased significantly. Students conducted this experiment with ease and in a short time frame, so this laboratory is conducive to merging with other data analysis techniques within a single laboratory period. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(6):515-520, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

Application of Circular Patch Plasty (Dor Procedure) or Linear Repair Techniques in the Treatment of Left Ventricular Aneurysms.

PubMed

Kaya, Ugur; Çolak, Abdurrahim; Becit, Necip; Ceviz, Munacettin; Kocak, Hikmet

2018-01-01

The aim of this study was to evaluate early clinical outcomes and echocardiographic measurements of the left ventricle in patients who underwent left ventricular aneurysm repair using two different techniques associated to myocardial revascularization. Eighty-nine patients (74 males, 15 females; mean age 58±8.4 years; range: 41 to 80 years) underwent post-infarction left ventricular aneurysm repair and myocardial revascularization performed between 1996 and 2016. Ventricular reconstruction was performed using endoventricular circular patch plasty (Dor procedure) (n=48; group A) or linear repair technique (n=41; group B). Multi-vessel disease in 55 (61.7%) and isolated left anterior descending (LAD) disease in 34 (38.2%) patients were identified. Five (5.6%) patients underwent aneurysmectomy alone, while the remaining 84 (94.3%) patients had aneurysmectomy with bypass. The mean number of grafts per patient was 2.1±1.2 with the Dor procedure and 2.9±1.3 with the linear repair technique. In-hospital mortality occurred in 4.1% and 7.3% in group A and group B, respectively (P>0.05). The results of our study demonstrate that post-infarction left ventricular aneurysm repair can be performed with both techniques with acceptable surgical risk and with satisfactory hemodynamic improvement.

Circular RNA is expressed across the eukaryotic tree of life.

PubMed

Wang, Peter L; Bao, Yun; Yee, Muh-Ching; Barrett, Steven P; Hogan, Gregory J; Olsen, Mari N; Dinneny, José R; Brown, Patrick O; Salzman, Julia

2014-01-01

An unexpectedly large fraction of genes in metazoans (human, mouse, zebrafish, worm, fruit fly) express high levels of circularized RNAs containing canonical exons. Here we report that circular RNA isoforms are found in diverse species whose most recent common ancestor existed more than one billion years ago: fungi (Schizosaccharomyces pombe and Saccharomyces cerevisiae), a plant (Arabidopsis thaliana), and protists (Plasmodium falciparum and Dictyostelium discoideum). For all species studied to date, including those in this report, only a small fraction of the theoretically possible circular RNA isoforms from a given gene are actually observed. Unlike metazoans, Arabidopsis, D. discoideum, P. falciparum, S. cerevisiae, and S. pombe have very short introns (∼ 100 nucleotides or shorter), yet they still produce circular RNAs. A minority of genes in S. pombe and P. falciparum have documented examples of canonical alternative splicing, making it unlikely that all circular RNAs are by-products of alternative splicing or 'piggyback' on signals used in alternative RNA processing. In S. pombe, the relative abundance of circular to linear transcript isoforms changed in a gene-specific pattern during nitrogen starvation. Circular RNA may be an ancient, conserved feature of eukaryotic gene expression programs.

Circular RNA Is Expressed across the Eukaryotic Tree of Life

PubMed Central

Wang, Peter L.; Bao, Yun; Yee, Muh-Ching; Barrett, Steven P.; Hogan, Gregory J.; Olsen, Mari N.; Dinneny, José R.; Brown, Patrick O.; Salzman, Julia

2014-01-01

An unexpectedly large fraction of genes in metazoans (human, mouse, zebrafish, worm, fruit fly) express high levels of circularized RNAs containing canonical exons. Here we report that circular RNA isoforms are found in diverse species whose most recent common ancestor existed more than one billion years ago: fungi (Schizosaccharomyces pombe and Saccharomyces cerevisiae), a plant (Arabidopsis thaliana), and protists (Plasmodium falciparum and Dictyostelium discoideum). For all species studied to date, including those in this report, only a small fraction of the theoretically possible circular RNA isoforms from a given gene are actually observed. Unlike metazoans, Arabidopsis, D. discoideum, P. falciparum, S. cerevisiae, and S. pombe have very short introns (∼100 nucleotides or shorter), yet they still produce circular RNAs. A minority of genes in S. pombe and P. falciparum have documented examples of canonical alternative splicing, making it unlikely that all circular RNAs are by-products of alternative splicing or ‘piggyback’ on signals used in alternative RNA processing. In S. pombe, the relative abundance of circular to linear transcript isoforms changed in a gene-specific pattern during nitrogen starvation. Circular RNA may be an ancient, conserved feature of eukaryotic gene expression programs. PMID:24609083

Three-dimensional hologram display system

NASA Technical Reports Server (NTRS)

Mintz, Frederick (Inventor); Chao, Tien-Hsin (Inventor); Bryant, Nevin (Inventor); Tsou, Peter (Inventor)

2009-01-01

The present invention relates to a three-dimensional (3D) hologram display system. The 3D hologram display system includes a projector device for projecting an image upon a display medium to form a 3D hologram. The 3D hologram is formed such that a viewer can view the holographic image from multiple angles up to 360 degrees. Multiple display media are described, namely a spinning diffusive screen, a circular diffuser screen, and an aerogel. The spinning diffusive screen utilizes spatial light modulators to control the image such that the 3D image is displayed on the rotating screen in a time-multiplexing manner. The circular diffuser screen includes multiple, simultaneously-operated projectors to project the image onto the circular diffuser screen from a plurality of locations, thereby forming the 3D image. The aerogel can use the projection device described as applicable to either the spinning diffusive screen or the circular diffuser screen.

Automatic and quantitative measurement of collagen gel contraction using model-guided segmentation

NASA Astrophysics Data System (ADS)

Chen, Hsin-Chen; Yang, Tai-Hua; Thoreson, Andrew R.; Zhao, Chunfeng; Amadio, Peter C.; Sun, Yung-Nien; Su, Fong-Chin; An, Kai-Nan

2013-08-01

Quantitative measurement of collagen gel contraction plays a critical role in the field of tissue engineering because it provides spatial-temporal assessment (e.g., changes of gel area and diameter during the contraction process) reflecting the cell behavior and tissue material properties. So far the assessment of collagen gels relies on manual segmentation, which is time-consuming and suffers from serious intra- and inter-observer variability. In this study, we propose an automatic method combining various image processing techniques to resolve these problems. The proposed method first detects the maximal feasible contraction range of circular references (e.g., culture dish) and avoids the interference of irrelevant objects in the given image. Then, a three-step color conversion strategy is applied to normalize and enhance the contrast between the gel and background. We subsequently introduce a deformable circular model which utilizes regional intensity contrast and circular shape constraint to locate the gel boundary. An adaptive weighting scheme was employed to coordinate the model behavior, so that the proposed system can overcome variations of gel boundary appearances at different contraction stages. Two measurements of collagen gels (i.e., area and diameter) can readily be obtained based on the segmentation results. Experimental results, including 120 gel images for accuracy validation, showed high agreement between the proposed method and manual segmentation with an average dice similarity coefficient larger than 0.95. The results also demonstrated obvious improvement in gel contours obtained by the proposed method over two popular, generic segmentation methods.

Circular electrode geometry metal-semiconductor-metal photodetectors

NASA Technical Reports Server (NTRS)

Mcaddo, James A. (Inventor); Towe, Elias (Inventor); Bishop, William L. (Inventor); Wang, Liang-Guo (Inventor)

1994-01-01

The invention comprises a high speed, metal-semiconductor-metal photodetector which comprises a pair of generally circular, electrically conductive electrodes formed on an optically active semiconductor layer. Various embodiments of the invention include a spiral, intercoiled electrode geometry and an electrode geometry comprised of substantially circular, concentric electrodes which are interposed. These electrode geometries result in photodetectors with lower capacitances, dark currents and lower inductance which reduces the ringing seen in the optical pulse response.

Circular polarimetry of fifteen interesting objects.

NASA Technical Reports Server (NTRS)

Kemp, J. C.; Wolstencroft, R. D.; Swedlund, J. B.

1972-01-01

The results of a search are presented for circular polarization of visible light in 15 objects, including two eclipsing binaries, six magnetic Ap stars, three planetary nebulae, Hubble's Nebula, M87, Sirius, and the Orion A region. On the whole, the results were null, down to typical upper limits for q of 0.01 per cent. A complete description of the used photoelastic polarimeter is given, with special attention to the incidental linear-circular conversion.

Electrostatic and Small-Signal Analysis of CMUTs With Circular and Square Anisotropic Plates.

PubMed

Funding la Cour, Mette; Christiansen, Thomas Lehrmann; Jensen, Jørgen Arendt; Thomsen, Erik Vilain

2015-08-01

Traditionally, capacitive micromachined ultrasonic transducers (CMUTs) are modeled using the isotropic plate equation, and this leads to deviations between analytical calculations and finite element modeling (FEM). In this paper, the deflection is calculated for both circular and square plates using the full anisotropic plate equation. It is shown that the anisotropic calculations match excellently with FEM, whereas an isotropic approach causes up to 10% deviations in deflection. For circular plates, an exact solution can be found. For square plates using the Galerkin method, and utilizing the symmetry of the silicon crystal, a compact and accurate expression for the deflection can be obtained. The deviation from FEM in center deflection is <0.1%. The theory of multilayer plates is also applied to the CMUT. The deflection of a square plate was measured on fabricated CMUTs using a white light interferometer. Fitting the plate parameter for the anisotropic calculated deflection to the measurement, a deviation of 0.07% is seen. Electrostatic and small-signal dynamic analysis are performed using energy considerations including anisotropy. The stable position, effective spring constant, pullin distance, and pull-in voltage are found for both circular and square anisotropic plates, and the pressure dependence is included by comparison with the corresponding analysis for a parallel plate. Measurements on fabricated devices with both circular and square plates subjected to increasing bias voltage are performed, and it is observed that the models including anisotropic effects are within the uncertainty interval of the measurements. Finally, a lumped element small-signal model for both circular and square anisotropic plates is derived to describe the dynamics of the CMUT.

Advantages of synchrotron radiation circular dichroism spectroscopy to study intrinsically disordered proteins.

PubMed

Kumagai, Patricia S; DeMarco, Ricardo; Lopes, Jose L S

2017-10-01

The unordered secondary structural content of an intrinsically disordered protein (IDP) is susceptible to conformational changes induced by many different external factors, such as the presence of organic solvents, removal of water, changes in temperature, binding to partner molecules, and interaction with lipids and/or other ligands. In order to characterize the high-flexibility nature of an IDP, circular dichroism (CD) spectroscopy is a particularly useful method due to its capability of monitoring both subtle and remarkable changes in different environments, relative ease in obtaining measurements, the small amount of sample required, and the capability for sample recovery (sample not damaged) and others. Using synchrotron radiation as the light source for CD spectroscopy represents the state-of-the-art version of this technique with feasibility of accessing the lower wavelength UV region, and therefore presenting a series of advantages over conventional circular dichroism (cCD) to monitor a protein conformational behavior, check protein stability, detect ligand binding, and many others. In this paper, we have performed a comparative study using cCD and SRCD methods for investigating the secondary structure and the conformational behavior of natively unfolded proteins: MEG-14 and soybean trypsin inhibitor. We show that the SRCD technique greatly improves the analysis and accuracy of the studies on the conformations of IDPs.

Comparison of single-stapling and hemi-double-stapling methods for intracorporeal esophagojejunostomy using a circular stapler after totally laparoscopic total gastrectomy.

PubMed

Amisaki, Masataka; Kihara, Kyoichi; Endo, Kanenori; Suzuki, Kazunori; Nakamura, Seiichi; Sawata, Takashi; Shimizu, Tetsu

2016-07-01

Laparoscopic total gastrectomy is not widely performed because of the difficulty of esophagojejunal reconstruction. This study analyzed complication rates of two different methods for reconstruction by a circular stapler after totally laparoscopic total gastrectomy (TLTG). Between 2010 and 2014, clinical data of 19 patients who underwent TLTG for gastric adenocarcinoma were collected retrospectively. There were two methods to fix the anvil of a circular stapler into the distal esophagus: In the single-stapling technique (SST) group, Endo-PSI(II) was used for purse-suturing on the distal esophagus for reconstruction, and in the hemi-double-stapling technique (hemi-DST) group, the esophagus was cut by linear stapler with the entry hole of the anvil shaft opened after inserting the anvil tail. In both groups, surgical procedures were the same, except for the reconstruction. All TLTGs were performed securely without mortality. Intracorporeal laparoscopic esophagojejunal anastomosis was performed successfully for all the patients. In the hemi-DST group, four patients experienced anastomotic stenosis, three of whom required endoscopic balloon dilation. In contrast, no stenosis was seen in the SST group (p = 0.033). Anastomosis with SST is preferred to that with hemi-DST to minimize postoperative complications.

Polar POLICRYPS diffractive structures generate cylindrical vector beams

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alj, Domenico; Caputo, Roberto, E-mail: roberto.caputo@fis.unical.it; Umeton, Cesare

2015-11-16

Local shaping of the polarization state of a light beam is appealing for a number of applications. This can be achieved by employing devices containing birefringent materials. In this article, we present one such enables converting a uniformly circularly polarized beam into a cylindrical vector beam (CVB). This device has been fabricated by exploiting the POLICRYPS (POlymer-LIquid CRYstals-Polymer-Slices) photocuring technique. It is a liquid-crystal-based optical diffraction grating featuring polar symmetry of the director alignment. We have characterized the resulting CVB profile and polarization for the cases of left and right circularly polarized incoming beams.

Orbital Transfer Techniques for Round-Trip Mars Missions

NASA Astrophysics Data System (ADS)

Landau, D. F.; Barbee, B. W.; Woolley, R. C.; Gershman, R.

2012-06-01

Efficient methods to transfer among a variety of Mars orbits is presented. Emphasis is placed on connecting arrival and departure interplanetary trajectories to an arbitrary circular target orbit for a hybrid human/robotic Mars sample return mission.

Stabilization of RNA hairpins using non-nucleotide linkers and circularization.

PubMed

Kiliszek, Agnieszka; Blaszczyk, Leszek; Kierzek, Ryszard; Rypniewski, Wojciech

2017-06-02

An RNA hairpin is an essential structural element of RNA. Hairpins play crucial roles in gene expression and intermolecular recognition but are also involved in the pathogenesis of some congenital diseases. Structural studies of the hairpin motifs are impeded by their thermodynamic instability, as they tend to unfold to form duplexes, especially at high concentrations required for crystallography or nuclear magnetic resonance spectroscopy. We have elaborated techniques to stabilize the RNA hairpins by linking the free ends of the RNA strand at the base of the hairpin stem. One method involves stilbene diether or hexaethylene glycol linkers and circularization by T4 RNA ligase. Another method uses click chemistry to stitch the RNA ends with a triazole linker. Both techniques are efficient and easy to perform. They should be useful in making stable, biologically relevant RNA constructs for structural studies. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

Influence of mass moment of inertia on normal modes of preloaded solar array mast

NASA Technical Reports Server (NTRS)

Armand, Sasan C.; Lin, Paul

1992-01-01

Earth-orbiting spacecraft often contain solar arrays or antennas supported by a preloaded mast. Because of weight and cost considerations, the structures supporting the spacecraft appendages are extremely light and flexible; therefore, it is vital to investigate the influence of all physical and structural parameters that may influence the dynamic behavior of the overall structure. The study primarily focuses on the mast for the space station solar arrays, but the formulations and the techniques developed in this study apply to any large and flexible mast in zero gravity. Furthermore, to determine the influence on the circular frequencies, the mass moment of inertia of the mast was incorporated into the governing equation of motion for bending. A finite element technique (MSC/NASTRAN) was used to verify the formulation. Results indicate that when the mast is relatively flexible and long, the mass moment inertia influences the circular frequencies.

Improved data visualization techniques for analyzing macromolecule structural changes.

PubMed

Kim, Jae Hyun; Iyer, Vidyashankara; Joshi, Sangeeta B; Volkin, David B; Middaugh, C Russell

2012-10-01

The empirical phase diagram (EPD) is a colored representation of overall structural integrity and conformational stability of macromolecules in response to various environmental perturbations. Numerous proteins and macromolecular complexes have been analyzed by EPDs to summarize results from large data sets from multiple biophysical techniques. The current EPD method suffers from a number of deficiencies including lack of a meaningful relationship between color and actual molecular features, difficulties in identifying contributions from individual techniques, and a limited ability to be interpreted by color-blind individuals. In this work, three improved data visualization approaches are proposed as techniques complementary to the EPD. The secondary, tertiary, and quaternary structural changes of multiple proteins as a function of environmental stress were first measured using circular dichroism, intrinsic fluorescence spectroscopy, and static light scattering, respectively. Data sets were then visualized as (1) RGB colors using three-index EPDs, (2) equiangular polygons using radar charts, and (3) human facial features using Chernoff face diagrams. Data as a function of temperature and pH for bovine serum albumin, aldolase, and chymotrypsin as well as candidate protein vaccine antigens including a serine threonine kinase protein (SP1732) and surface antigen A (SP1650) from S. pneumoniae and hemagglutinin from an H1N1 influenza virus are used to illustrate the advantages and disadvantages of each type of data visualization technique. Copyright © 2012 The Protein Society.

Improved data visualization techniques for analyzing macromolecule structural changes

PubMed Central

Kim, Jae Hyun; Iyer, Vidyashankara; Joshi, Sangeeta B; Volkin, David B; Middaugh, C Russell

2012-01-01

The empirical phase diagram (EPD) is a colored representation of overall structural integrity and conformational stability of macromolecules in response to various environmental perturbations. Numerous proteins and macromolecular complexes have been analyzed by EPDs to summarize results from large data sets from multiple biophysical techniques. The current EPD method suffers from a number of deficiencies including lack of a meaningful relationship between color and actual molecular features, difficulties in identifying contributions from individual techniques, and a limited ability to be interpreted by color-blind individuals. In this work, three improved data visualization approaches are proposed as techniques complementary to the EPD. The secondary, tertiary, and quaternary structural changes of multiple proteins as a function of environmental stress were first measured using circular dichroism, intrinsic fluorescence spectroscopy, and static light scattering, respectively. Data sets were then visualized as (1) RGB colors using three-index EPDs, (2) equiangular polygons using radar charts, and (3) human facial features using Chernoff face diagrams. Data as a function of temperature and pH for bovine serum albumin, aldolase, and chymotrypsin as well as candidate protein vaccine antigens including a serine threonine kinase protein (SP1732) and surface antigen A (SP1650) from S. pneumoniae and hemagglutinin from an H1N1 influenza virus are used to illustrate the advantages and disadvantages of each type of data visualization technique. PMID:22898970

Sealing Assembly for Sealing a Port and the Like

NASA Technical Reports Server (NTRS)

Haas, Jon W. (Inventor); Haupt, Charles W. (Inventor)

2000-01-01

The sealing assembly for a port of a valve or the like is disclosed. In detail, the sealing assembly includes the port having a circular shaped end with a circular shaped knife-edge thereon. The sealing assembly further includes a hollow cap having a closed first end with an aperture therethrough and an open second end. The cap further includes internal threads adapted to mate with the external threads of the port. A gasket is mounted within the cap having flat first and second principle sides and made of a deformable metal, the first principle side of the gasket for mounting against the circular shaped knife edge of the port. A plunger having a circular shaped disc portion is adapted to fit within the hollow cap and is engagable with the first principle surface of the gasket and includes a shaft portion extending out of the aperture. The cap and shaft of the plunger include external wrenching flats. Thus when the cap is screwed onto the port and the plunger is prevented from rotating by a wrench mounted on the wrenching flats of the shaft portion of the plunger, the gasket is forced into engagement with the knife edge in pure compression and no rotation of the gasket occurs causing the knife edge to locally deform the gasket sealing of the port.

Electron beam diagnostic system using computed tomography and an annular sensor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elmer, John W.; Teruya, Alan T.

2015-08-11

A system for analyzing an electron beam including a circular electron beam diagnostic sensor adapted to receive the electron beam, the circular electron beam diagnostic sensor having a central axis; an annular sensor structure operatively connected to the circular electron beam diagnostic sensor, wherein the sensor structure receives the electron beam; a system for sweeping the electron beam radially outward from the central axis of the circular electron beam diagnostic sensor to the annular sensor structure wherein the electron beam is intercepted by the annular sensor structure; and a device for measuring the electron beam that is intercepted by themore » annular sensor structure.« less

Electron beam diagnostic system using computed tomography and an annular sensor

DOEpatents

Elmer, John W.; Teruya, Alan T.

2014-07-29

A system for analyzing an electron beam including a circular electron beam diagnostic sensor adapted to receive the electron beam, the circular electron beam diagnostic sensor having a central axis; an annular sensor structure operatively connected to the circular electron beam diagnostic sensor, wherein the sensor structure receives the electron beam; a system for sweeping the electron beam radially outward from the central axis of the circular electron beam diagnostic sensor to the annular sensor structure wherein the electron beam is intercepted by the annular sensor structure; and a device for measuring the electron beam that is intercepted by the annular sensor structure.

Azimuthally invariant Mueller-matrix mapping of biological optically anisotropic network

NASA Astrophysics Data System (ADS)

Ushenko, Yu. O.; Vanchuliak, O.; Bodnar, G. B.; Ushenko, V. O.; Grytsyuk, M.; Pavlyukovich, N.; Pavlyukovich, O. V.; Antonyuk, O.

2017-09-01

A new technique of Mueller-matrix mapping of polycrystalline structure of histological sections of biological tissues is suggested. The algorithms of reconstruction of distribution of parameters of linear and circular dichroism of histological sections liver tissue of mice with different degrees of severity of diabetes are found. The interconnections between such distributions and parameters of linear and circular dichroism of liver of mice tissue histological sections are defined. The comparative investigations of coordinate distributions of parameters of amplitude anisotropy formed by Liver tissue with varying severity of diabetes (10 days and 24 days) are performed. The values and ranges of change of the statistical (moments of the 1st - 4th order) parameters of coordinate distributions of the value of linear and circular dichroism are defined. The objective criteria of cause of the degree of severity of the diabetes differentiation are determined.

Quantized circular photogalvanic effect in Weyl semimetals

NASA Astrophysics Data System (ADS)

de Juan, Fernando; Grushin, Adolfo G.; Morimoto, Takahiro; Moore, Joel E.

The circular photogalvanic effect (CPGE) is the part of a photocurrent that switches depending on the sense of circular polarization of the incident light. It has been consistently observed in systems without inversion symmetry and depends on non-universal material details. We find that in a class of Weyl semimetals (e.g. SrSi2) and three-dimensional Rashba materials (e.g. doped Te) without inversion and mirror symmetries, the CPGE trace is effectively Quantized in terms of the combination of fundamental constants e3/h2 cɛ0 with no material-dependent parameters. This is so because the CPGE directly measures the topological charge of Weyl points near the Fermi surface, and non-quantized corrections from disorder and additional bands can be small over a significant range of incident frequencies. Moreover, the magnitude of the CPGE induced by a Weyl node is relatively large, which enables the direct detection of the monopole charge with current techniques.

Quantized circular photogalvanic effect in Weyl semimetals

NASA Astrophysics Data System (ADS)

de Juan, Fernando; Grushin, Adolfo G.; Morimoto, Takahiro; Moore, Joel E.

2017-07-01

The circular photogalvanic effect (CPGE) is the part of a photocurrent that switches depending on the sense of circular polarization of the incident light. It has been consistently observed in systems without inversion symmetry and depends on non-universal material details. Here we find that in a class of Weyl semimetals (for example, SrSi2) and three-dimensional Rashba materials (for example, doped Te) without inversion and mirror symmetries, the injection contribution to the CPGE trace is effectively quantized in terms of the fundamental constants e, h, c and with no material-dependent parameters. This is so because the CPGE directly measures the topological charge of Weyl points, and non-quantized corrections from disorder and additional bands can be small over a significant range of incident frequencies. Moreover, the magnitude of the CPGE induced by a Weyl node is relatively large, which enables the direct detection of the monopole charge with current techniques.

Quantitative characterization of nanoscale polycrystalline magnets with electron magnetic circular dichroism.

PubMed

Muto, Shunsuke; Rusz, Ján; Tatsumi, Kazuyoshi; Adam, Roman; Arai, Shigeo; Kocevski, Vancho; Oppeneer, Peter M; Bürgler, Daniel E; Schneider, Claus M

2014-01-01

Electron magnetic circular dichroism (EMCD) allows the quantitative, element-selective determination of spin and orbital magnetic moments, similar to its well-established X-ray counterpart, X-ray magnetic circular dichroism (XMCD). As an advantage over XMCD, EMCD measurements are made using transmission electron microscopes, which are routinely operated at sub-nanometre resolution, thereby potentially allowing nanometre magnetic characterization. However, because of the low intensity of the EMCD signal, it has not yet been possible to obtain quantitative information from EMCD signals at the nanoscale. Here we demonstrate a new approach to EMCD measurements that considerably enhances the outreach of the technique. The statistical analysis introduced here yields robust quantitative EMCD signals. Moreover, we demonstrate that quantitative magnetic information can be routinely obtained using electron beams of only a few nanometres in diameter without imposing any restriction regarding the crystalline order of the specimen.

Ball-morph: definition, implementation, and comparative evaluation.

PubMed

Whited, Brian; Rossignac, Jaroslaw Jarek

2011-06-01

We define b-compatibility for planar curves and propose three ball morphing techniques between pairs of b-compatible curves. Ball-morphs use the automatic ball-map correspondence, proposed by Chazal et al., from which we derive different vertex trajectories (linear, circular, and parabolic). All three morphs are symmetric, meeting both curves with the same angle, which is a right angle for the circular and parabolic. We provide simple constructions for these ball-morphs and compare them to each other and other simple morphs (linear-interpolation, closest-projection, curvature-interpolation, Laplace-blending, and heat-propagation) using six cost measures (travel-distance, distortion, stretch, local acceleration, average squared mean curvature, and maximum squared mean curvature). The results depend heavily on the input curves. Nevertheless, we found that the linear ball-morph has consistently the shortest travel-distance and the circular ball-morph has the least amount of distortion.

Wholefield displacement measurements using speckle image processing techniques for crash tests

NASA Astrophysics Data System (ADS)

Sriram, P.; Hanagud, S.; Ranson, W. F.

The digital correlation scheme of Peters et al. (1983) was extended to measure out-of-plane deformations, using a white light projection speckle technique. A simple ray optic theory and the digital correlation scheme are outlined. The technique was applied successfully to measure out-of-plane displacements of initially flat rotorcraft structures (an acrylic circular plate and a steel cantilever beam), using a low cost video camera and a desktop computer. The technique can be extended to measurements of three-dimensional deformations and dynamic deformations.

Ultrasonic velocity profiling rheometry based on a widened circular Couette flow

NASA Astrophysics Data System (ADS)

Shiratori, Takahisa; Tasaka, Yuji; Oishi, Yoshihiko; Murai, Yuichi

2015-08-01

We propose a new rheometry for characterizing the rheological properties of fluids. The technique produces flow curves, which represent the relationship between the fluid shear rate and shear stress. Flow curves are obtained by measuring the circumferential velocity distribution of tested fluids in a circular Couette system, using an ultrasonic velocity profiling technique. By adopting a widened gap of concentric cylinders, a designed range of the shear rate is obtained so that velocity profile measurement along a single line directly acquires flow curves. To reduce the effect of ultrasonic noise on resultant flow curves, several fitting functions and variable transforms are examined to best approximate the velocity profile without introducing a priori rheological models. Silicone oil, polyacrylamide solution, and yogurt were used to evaluate the applicability of this technique. These substances are purposely targeted as examples of Newtonian fluids, shear thinning fluids, and opaque fluids with unknown rheological properties, respectively. We find that fourth-order Chebyshev polynomials provide the most accurate representation of flow curves in the context of model-free rheometry enabled by ultrasonic velocity profiling.

A survey of various enhancement techniques for square rings antennas

NASA Astrophysics Data System (ADS)

Mumin, Abdul Rashid O.; Alias, Rozlan; Abdullah, Jiwa; Abdulhasan, Raed Abdulkareem; Ali, Jawad; Dahlan, Samsul Haimi; Awaleh, Abdisamad A.

2017-09-01

The square ring shape becomes a famous reconfiguration on antenna design. The researchers have been developed the square ring by different configurations. It has high efficiency and simple calculation method. The performance enhancement for an antenna is the main reason to use this setting. Furthermore, the multi-objectives for the antenna also are considered. In this paper, different studies of square ring shape are discussed. This shape is developed in five different techniques, which are the gain enhancement, dual band antenna, reconfigurable antenna, CSRR, and circularly polarization. Moreover, the validation between these configurations also demonstrates for square ring shapes. In particular, the square ring slot improved the gain by 4.3 dB, provide dual band resonance at 1.4 and 2.6 GHz while circular polarization at 1.54 GHz, and multi-mode antenna. However, square ring strip achieved an excellent band rejection on UWB antenna at 5.5 GHz. The square ring slot length is the most influential factor on the antenna performance, which refers to the free space wavelength. Finally, comparisons between these techniques are presented.

The Detection of Radiated Modes from Ducted Fan Engines

NASA Technical Reports Server (NTRS)

Farassat, F.; Nark, Douglas M.; Thomas, Russell H.

2001-01-01

The bypass duct of an aircraft engine is a low-pass filter allowing some spinning modes to radiate outside the duct. The knowledge of the radiated modes can help in noise reduction, as well as the diagnosis of noise generation mechanisms inside the duct. We propose a nonintrusive technique using a circular microphone array outside the engine measuring the complex noise spectrum on an arc of a circle. The array is placed at various axial distances from the inlet or the exhaust of the engine. Using a model of noise radiation from the duct, an overdetermined system of linear equations is constructed for the complex amplitudes of the radial modes for a fixed circumferential mode. This system of linear equations is generally singular, indicating that the problem is illposed. Tikhonov regularization is employed to solve this system of equations for the unknown amplitudes of the radiated modes. An application of our mode detection technique using measured acoustic data from a circular microphone array is presented. We show that this technique can reliably detect radiated modes with the possible exception of modes very close to cut-off.

Measurement of Stress Distribution Around a Circular Hole in a Plate Under Bending Moment Using Phase-shifting Method with Reflective Polariscope Arrangement

NASA Astrophysics Data System (ADS)

Baek, Tae Hyun

Photoelasticity is one of the most widely used whole-field optical methods for stress analysis. The technique of birefringent coatings, also called the method of photoelastic coatings, extends the classical procedures of model photoelasticity to the measurement of surface strains in opaque models made of any structural material. Photoelastic phase-shifting method can be used for the determination of the phase values of isochromatics and isoclinics. In this paper, photoelastic phase-shifting technique and conventional Babinet-Soleil compensation method were utilized to analyze a specimen with a triangular hole and a circular hole under bending. Photoelastic phase-shifting technique is whole-field measurement. On the other hand, conventional compensation method is point measurement. Three groups of results were obtained by phase-shifting method with reflective polariscope arrangement, conventional compensation method and FEM simulation, respectively. The results from the first two methods agree with each other relatively well considering experiment error. The advantage of photoelastic phase-shifting method is that it is possible to measure the stress distribution accurately close to the edge of holes.

Eddy current heating in magnetic refrigerators

NASA Technical Reports Server (NTRS)

Kittel, Peter

1990-01-01

Eddy current heating can be a significant source of parasitic heating in low temperature magnetic refrigerators. To study this problem a technique to approximate the heating due to eddy currents has been developed. A formula is presented for estimating the heating within a variety of shapes commonly found in magnetic refrigerators. These shapes include circular, square, and rectangular rods; cylindrical and split cylindrical shells; wire loops; and 'coil foil. One set of components evaluated are different types of thermal radiation shields. This comparison shows that a simple split shield is almost as effective (only 23 percent more heating) as using a shield, with the same axial thermal conductivity, made of 'coil foil'.

Geometrically derived difference formulae for the numerical integration of trajectory problems

NASA Technical Reports Server (NTRS)

Mcleod, R. J. Y.; Sanz-Serna, J. M.

1981-01-01

The term 'trajectory problem' is taken to include problems that can arise, for instance, in connection with contour plotting, or in the application of continuation methods, or during phase-plane analysis. Geometrical techniques are used to construct difference methods for these problems to produce in turn explicit and implicit circularly exact formulae. Based on these formulae, a predictor-corrector method is derived which, when compared with a closely related standard method, shows improved performance. It is found that this latter method produces spurious limit cycles, and this behavior is partly analyzed. Finally, a simple variable-step algorithm is constructed and tested.

Comparative Analysis of Sequential Proximal Optimizing Technique Versus Kissing Balloon Inflation Technique in Provisional Bifurcation Stenting: Fractal Coronary Bifurcation Bench Test.

PubMed

Finet, Gérard; Derimay, François; Motreff, Pascal; Guerin, Patrice; Pilet, Paul; Ohayon, Jacques; Darremont, Olivier; Rioufol, Gilles

2015-08-24

This study used a fractal bifurcation bench model to compare 6 optimization sequences for coronary bifurcation provisional stenting, including 1 novel sequence without kissing balloon inflation (KBI), comprising initial proximal optimizing technique (POT) + side-branch inflation (SBI) + final POT, called "re-POT." In provisional bifurcation stenting, KBI fails to improve the rate of major adverse cardiac events. Proximal geometric deformation increases the rate of in-stent restenosis and target lesion revascularization. A bifurcation bench model was used to compare KBI alone, KBI after POT, KBI with asymmetric inflation pressure after POT, and 2 sequences without KBI: initial POT plus SBI, and initial POT plus SBI with final POT (called "re-POT"). For each protocol, 5 stents were tested using 2 different drug-eluting stent designs: that is, a total of 60 tests. Compared with the classic KBI-only sequence and those associating POT with modified KBI, the re-POT sequence gave significantly (p < 0.05) better geometric results: it reduced SB ostium stent-strut obstruction from 23.2 ± 6.0% to 5.6 ± 8.3%, provided perfect proximal stent apposition with almost perfect circularity (ellipticity index reduced from 1.23 ± 0.02 to 1.04 ± 0.01), reduced proximal area overstretch from 24.2 ± 7.6% to 8.0 ± 0.4%, and reduced global strut malapposition from 40 ± 6.2% to 2.6 ± 1.4%. In comparison with 5 other techniques, the re-POT sequence significantly optimized the final result of provisional coronary bifurcation stenting, maintaining circular geometry while significantly reducing SB ostium strut obstruction and global strut malapposition. These experimental findings confirm that provisional stenting may be optimized more effectively without KBI using re-POT. Copyright © 2015 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

An Assessment of the Usefulness of Water Tunnels for Aerodynamic Investigations

DTIC Science & Technology

2012-12-01

a wide range of research projects, including the prediction of the performance of gas- turbine engines under conditions of pulsating flow, parametric...number-insensitive flows is water-tunnel testing of a thin rectangular flat plate having an aspect ratio of 2 – see Figure 4 from Kaplan , Altman & Ol... Kaplan , Altman & Ol, (2007). 7. Flow Over Circular-Type Bodies 7.1 Circular Cylinders The flow around a circular cylinder located at right angles

Torque sensor having a spoked sensor element support structure

NASA Technical Reports Server (NTRS)

Lurie, Boris J. (Inventor); Schier, J. Alan (Inventor)

1990-01-01

Piezoelectric sensor devices are attached across pairs of circularly arranged spokes arrayed on the periphery of an annular ring. The sensor devices each include a preloaded steel ball mounting arrangement for mounting a piezoelectric sensor element. A first circular interface plate on one side of the sensor structure attaches to alternate one of the spokes, and a circular interface plate on the opposite side of the same diameter as the first interface plate attaches to the remaining spokes.

76 FR 60590 - Environmental Justice; Proposed Circular

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-29

..., Metropolitan Planning Organizations, public transportation providers, and other recipients of FTA funds on how to fully engage environmental justice populations in the public transportation decisionmaking process...--Environmental Justice and Public Transportation B. Chapter II--Tools and Techniques for Conducting an...

Multimode analysis of highly tunable, quantum cascade powered, circular graphene spaser

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jayasekara, Charith, E-mail: charith.jayasekara@monash.edu; Premaratne, Malin; Stockman, Mark I.

2015-11-07

We carried out a detailed analysis of a circular graphene spaser made of a circular graphene flake and a quantum cascade well structure. Owing to unique properties of graphene and quantum cascade well structure, the proposed design shows high mechanical and thermal stability and low optical losses. Additionally, operation characteristics of the model are analysed and tunability of the device is demonstrated. Some advantages of the proposed design include compact size, lower power operation, and the ability to set the operating wavelength over a wide range from Mid-IR to Near-IR. Thus, it can have wide spread applications including designing ofmore » ultracompact and ultrafast devices, nanoscopy and biomedical applications.« less

Combustor with non-circular head end

DOEpatents

Kim, Won -Wook; McMahan, Kevin Weston

2015-09-29

The present application provides a combustor for use with a gas turbine engine. The combustor may include a head end with a non-circular configuration, a number of fuel nozzles positioned about the head end, and a transition piece extending downstream of the head end.

Performance of two-lobe hole-entry hybrid journal bearing system under the combined influence of textured surface and couple stress lubricant

NASA Astrophysics Data System (ADS)

Khatri, Chandra B.; Sharma, Satish C.

2018-02-01

Textured surface in journal bearings is becoming an important area of investigation during the last few years. Surface textures have the shapes of micro-dimple with a small diameter and depth having order of magnitude of bearing clearance. This paper presents the influence of couple stress lubricant on the circular and non-circular hole-entry hybrid journal bearing system and reports the comparative study between the textured and non-textured circular/non-circular hybrid journal bearing system. The governing Reynolds equation has been modified for the couple stress lubricant flow in the clearance of bearing and journal. The FEM technique has been applied to solve the modified Reynolds equation together with restrictor flow equation. The numerically simulated results indicate that the influence of couple stress lubricant is significantly more in textured journal bearing than that of non-textured journal bearing. Further, it has been observed that the textured two-lobe (δ = 1.1) hybrid journal bearing lubricated with couple stress lubricant provides larger values of fluid film stiffness coefficients and stability threshold speed against other bearings studied in the present paper.

Comparing the Cognitive Process of Circular Causality in Two Patients with Strokes through Qualitative Analysis.

PubMed

Derakhshanrad, Seyed Alireza; Piven, Emily; Ghoochani, Bahareh Zeynalzadeh

2017-10-01

Walter J. Freeman pioneered the neurodynamic model of brain activity when he described the brain dynamics for cognitive information transfer as the process of circular causality at intention, meaning, and perception (IMP) levels. This view contributed substantially to establishment of the Intention, Meaning, and Perception Model of Neuro-occupation in occupational therapy. As described by the model, IMP levels are three components of the brain dynamics system, with nonlinear connections that enable cognitive function to be processed in a circular causality fashion, known as Cognitive Process of Circular Causality (CPCC). Although considerable research has been devoted to study the brain dynamics by sophisticated computerized imaging techniques, less attention has been paid to study it through investigating the adaptation process of thoughts and behaviors. To explore how CPCC manifested thinking and behavioral patterns, a qualitative case study was conducted on two matched female participants with strokes, who were of comparable ages, affected sides, and other characteristics, except for their resilience and motivational behaviors. CPCC was compared by matrix analysis between two participants, using content analysis with pre-determined categories. Different patterns of thinking and behavior may have happened, due to disparate regulation of CPCC between two participants.

Synthetic-Aperture Coherent Imaging From A Circular Path

NASA Technical Reports Server (NTRS)

Jin, Michael Y.

1995-01-01

Imaging algorithms based on exact point-target responses. Developed for use in reconstructing image of target from data gathered by radar, sonar, or other transmitting/receiving coherent-signal sensory apparatus following circular observation path around target. Potential applications include: Wide-beam synthetic-aperture radar (SAR) from aboard spacecraft in circular orbit around target planet; SAR from aboard airplane flying circular course at constant elevation around central ground point, toward which spotlight radar beam pointed; Ultrasonic reflection tomography in medical setting, using one transducer moving in circle around patient or else multiple transducers at fixed positions on circle around patient; and Sonar imaging of sea floor to high resolution, without need for large sensory apparatus.

Circular RNAs are abundant, conserved, and associated with ALU repeats

PubMed Central

Jeck, William R.; Sorrentino, Jessica A.; Wang, Kai; Slevin, Michael K.; Burd, Christin E.; Liu, Jinze; Marzluff, William F.; Sharpless, Norman E.

2013-01-01

Circular RNAs composed of exonic sequence have been described in a small number of genes. Thought to result from splicing errors, circular RNA species possess no known function. To delineate the universe of endogenous circular RNAs, we performed high-throughput sequencing (RNA-seq) of libraries prepared from ribosome-depleted RNA with or without digestion with the RNA exonuclease, RNase R. We identified >25,000 distinct RNA species in human fibroblasts that contained non-colinear exons (a “backsplice”) and were reproducibly enriched by exonuclease degradation of linear RNA. These RNAs were validated as circular RNA (ecircRNA), rather than linear RNA, and were more stable than associated linear mRNAs in vivo. In some cases, the abundance of circular molecules exceeded that of associated linear mRNA by >10-fold. By conservative estimate, we identified ecircRNAs from 14.4% of actively transcribed genes in human fibroblasts. Application of this method to murine testis RNA identified 69 ecircRNAs in precisely orthologous locations to human circular RNAs. Of note, paralogous kinases HIPK2 and HIPK3 produce abundant ecircRNA from their second exon in both humans and mice. Though HIPK3 circular RNAs contain an AUG translation start, it and other ecircRNAs were not bound to ribosomes. Circular RNAs could be degraded by siRNAs and, therefore, may act as competing endogenous RNAs. Bioinformatic analysis revealed shared features of circularized exons, including long bordering introns that contained complementary ALU repeats. These data show that ecircRNAs are abundant, stable, conserved and nonrandom products of RNA splicing that could be involved in control of gene expression. PMID:23249747

Intrinsic magnetic properties of bimetallic nanoparticles elaborated by cluster beam deposition.

PubMed

Dupuis, V; Khadra, G; Hillion, A; Tamion, A; Tuaillon-Combes, J; Bardotti, L; Tournus, F

2015-11-14

In this paper, we present some specific chemical and magnetic order obtained very recently on characteristic bimetallic nanoalloys prepared by mass-selected Low Energy Cluster Beam Deposition (LECBD). We study how the competition between d-atom hybridization, complex structure, morphology and chemical affinity affects their intrinsic magnetic properties at the nanoscale. The structural and magnetic properties of these nanoalloys were investigated using various experimental techniques that include High Resolution Transmission Electron Microscopy (HRTEM), Superconducting Quantum Interference Device (SQUID) magnetometry, as well as synchrotron techniques such as Extended X-ray Absorption Fine Structure (EXAFS) and X-ray Magnetic Circular Dichroism (XMCD). Depending on the chemical nature of the nanoalloys we observe different magnetic responses compared to their bulk counterparts. In particular, we show how specific relaxation in nanoalloys impacts their magnetic anisotropy; and how finite size effects (size reduction) inversely enhance their magnetic moment.

A Combined FEM/MoM/GTD Technique To Analyze Elliptically Polarized Cavity-Backed Antennas With Finite Ground Plane

NASA Technical Reports Server (NTRS)

Reddy, C. J.; Deshpande, M. D.; Fralick, D. T.; Cockrell, C. R.; Beck, F. B.

1996-01-01

Radiation pattern prediction analysis of elliptically polarized cavity-backed aperture antennas in a finite ground plane is performed using a combined Finite Element Method/Method of Moments/Geometrical Theory of Diffraction (FEM/MoM/GTD) technique. The magnetic current on the cavity-backed aperture in an infinite ground plane is calculated using the combined FEM/MoM analysis. GTD, including the slope diffraction contribution, is used to calculate the diffracted fields caused by both soft and hard polarizations at the edges of the finite ground plane. Explicit expressions for regular diffraction coefficients and slope diffraction coefficients are presented. The slope of the incident magnetic field at the diffraction points is derived and analytical expressions are presented. Numerical results for the radiation patterns of a cavity-backed circular spiral microstrip patch antenna excited by a coaxial probe in a finite rectangular ground plane are computed and compared with experimental results.

Metal-assisted and microwave accelerated-evaporative crystallization: Application to lysozyme protein

NASA Astrophysics Data System (ADS)

Mauge-Lewis, Kevin

In response to the growing need for new crystallization techniques that afford for rapid processing times along with control over crystal size and distribution, the Aslan Research Group has recently demonstrated the use of Metal-Assisted and Microwave-Accelerated Evaporative Crystallization MA-MAEC technique in conjunction with metal nanoparticles and nanostructures for the crystallization of amino acids and organic small molecules. In this study, we have employed the newly developed MA-MAEC technique to the accelerated crystallization of chicken egg-white lysozyme on circular crystallization platforms in order to demonstrate the proof-of-principle application of the method for protein crystallization. The circular crystallization platforms are constructed in-house from poly (methyl methacrylate) (PMMA) and silver nanoparticle films (SNFs), indium tin oxide (ITO) and iron nano-columns. In this study, we prove the MA-MAEC method to be a more effective technique in the rapid crystallization of macromolecules in comparison to other conventional methods. Furthermore, we demonstrate the use of the novel iCrystal system, which incorporates the use of continuous, low wattage heating to facilitate the rapid crystallization of the lysozyme while still retaining excellent crystal quality. With the incorporation of the iCrystal system, we observe crystallization times that are even shorter than those produced by the MA-MAEC technique using a conventional microwave oven in addition to significantly improved crystal quality.

Investigating large-scale secondary circulations within impact crater topographies in a refractive index-matched facility

NASA Astrophysics Data System (ADS)

Blois, Gianluca; Kim, Taehoon; Bristow, Nathan; Day, Mackenzie; Kocurek, Gary; Anderson, William; Christensen, Kenneth

2017-11-01

Impact craters, common large-scale topographic features on the surface of Mars, are circular depressions delimited by a sharp ridge. A variety of crater fill morphologies exist, suggesting that complex intracrater circulations affect their evolution. Some large craters (diameter >10 km), particularly at mid latitudes on Mars, exhibit a central mound surrounded by circular moat. Foremost among these examples is Gale crater, landing site of NASA's Curiosity rover, since large-scale climatic processes early in in the history of Mars are preserved in the stratigraphic record of the inner mound. Investigating the intracrater flow produced by large scale winds aloft Mars craters is key to a number of important scientific issues including ongoing research on Mars paleo-environmental reconstruction and the planning of future missions (these results must be viewed in conjunction with the affects of radial katabatibc flows, the importance of which is already established in preceding studies). In this work we consider a number of crater shapes inspired by Gale morphology, including idealized craters. Access to the flow field within such geometrically complex topography is achieved herein using a refractive index matched approach. Instantaneous velocity maps, using both planar and volumetric PIV techniques, are presented to elucidate complex three-dimensional flow within the crater. In addition, first- and second-order statistics will be discussed in the context of wind-driven (aeolian) excavation of crater fill.

Advanced Applications of Vibrational Circular Dichroism: from Small Chiral Molecules to Fibrils

NASA Astrophysics Data System (ADS)

Dukor, Rina K.

2017-06-01

Vibrational Circular Dichroism (VCD), first discovered in the early 1970s, and commercialized in the late 1990's, is finally coming of age! No longer a curiosity of the few selected academic groups, it is now used by all major pharmaceutical companies, regulatory agencies, government labs and academic institutions. The main application for the technology has been determination of absolute configuration of small pharmaceutical molecules. In more recent years, this has extended to more complicated molecules such as natural products with many chiral centers and conformational flexibility. Other applications include determination of enantiomeric purity, chiral polymers, and characterization of other biological molecules such as proteins, carohydrates and nucleic acids. One of the most fascinating discoveries in the VCD field has been been unusual enhancement in intensity for proteins that form fibrils. We have demonstrated sensitivity of VCD to in situ solution-phase probe of the process of fibrillogenesis and subsequent development that currently can only be studied in detail with dried samples by such techniques as scanning electron microscopy or atomic force microscopy. We have further shown that several different proteins, that in their native state have different secondary structures, have a very similar unique signature of mature fibrils. In this presentation, we will discuss fundamentals of VCD, demonstrate a few examples of different applications and showcase the sensitivity to structure of fibrils, including new results on micro-sampling.

Physical Modeling of Flow Over Gale Crater, Mars: Laboratory Measurements of Basin Secondary Circulations

NASA Astrophysics Data System (ADS)

Bristow, N.; Blois, G.; Kim, T.; Anderson, W.; Day, M. D.; Kocurek, G.; Christensen, K. T.

2017-12-01

Impact craters, common large-scale topographic features on the surface of Mars, are circular depressions delimited by a sharp ridge. A variety of crater fill morphologies exist, suggesting that complex intracrater circulations affect their evolution. Some large craters (diameter > 10 km), particularly at mid latitudes on Mars, exhibit a central mound surrounded by circular moat. Foremost among these examples is Gale crater, landing site of NASA's Curiosity rover, since large-scale climatic processes early in in the history of Mars are preserved in the stratigraphic record of the inner mound. Investigating the intracrater flow produced by large scale winds aloft Mars craters is key to a number of important scientific issues including ongoing research on Mars paleo-environmental reconstruction and the planning of future missions (these results must be viewed in conjunction with the affects of radial katabatibc flows, the importance of which is already established in preceding studies). In this work we consider a number of crater shapes inspired by Gale morphology, including idealized craters. Access to the flow field within such geometrically complex topography is achieved herein using a refractive index matched approach. Instantaneous velocity maps, using both planar and volumetric PIV techniques, are presented to elucidate complex three-dimensional flow within the crater. In addition, first- and second-order statistics will be discussed in the context of wind-driven (aeolian) excavation of crater fill.

Paper-based microreactor integrating cell culture and subsequent immunoassay for the investigation of cellular phosphorylation.

PubMed

Lei, Kin Fong; Huang, Chia-Hao

2014-12-24

Investigation of cellular phosphorylation and signaling pathway has recently gained much attention for the study of pathogenesis of cancer. Related conventional bioanalytical operations for this study including cell culture and Western blotting are time-consuming and labor-intensive. In this work, a paper-based microreactor has been developed to integrate cell culture and subsequent immunoassay on a single paper. The paper-based microreactor was a filter paper with an array of circular zones for running multiple cell cultures and subsequent immunoassays. Cancer cells were directly seeded in the circular zones without hydrogel encapsulation and cultured for 1 day. Subsequently, protein expressions including structural, functional, and phosphorylated proteins of the cells could be detected by their specific antibodies, respectively. Study of the activation level of phosphorylated Stat3 of liver cancer cells stimulated by IL-6 cytokine was demonstrated by the paper-based microreactor. This technique can highly reduce tedious bioanalytical operation and sample and reagent consumption. Also, the time required by the entire process can be shortened. This work provides a simple and rapid screening tool for the investigation of cellular phosphorylation and signaling pathway for understanding the pathogenesis of cancer. In addition, the operation of the paper-based microreactor is compatible to the molecular biological training, and therefore, it has the potential to be developed for routine protocol for various research areas in conventional bioanalytical laboratories.

Correlations for heat transfer coefficient and friction factor for turbulent flow of air through square and hexagonal ducts with twisted tape insert

NASA Astrophysics Data System (ADS)

Yadav, Rupesh J.; Kore, Sandeep S.; Joshi, Prathamesh S.

2018-05-01

The experimental and numerical Nusselt number and friction factor investigation for turbulent flow through a non-circular duct with twisted-tape inserts have been presented. The non-circular ducts include square, hexagonal duct. The results of non-circular ducts are compared with circular duct. All the ducts have same equivalent diameter. The twist ratios used for the experiment are Y = 3.5, 4.5, 5.5 and 6.5. Experiments were carried out on square duct, hexagonal duct and circular duct. The Reynolds number lied between 10,000 and 1, 05,000. The present study is restricted to the flow of air at Pr = 0.7 only and within a narrow temperature range of 40 to 75 ΟC, within which the compressible nature of air can be neglected. The results reveal that, both Nusselt number and friction factor increases as the side of non-circular duct increases. Maximum Nusselt number and friction factor is obtained in case of circular duct with twisted tape. Further the correlations of Nu and f are given for different non circular duct with twisted tape insert for engineering applications for the turbulent regime. Since the thermal performance factor (η) is observed to be within the range of 0.8 to 1.13 for both circular and noncircular ducts, the overall benefit of using twisted tape in the flow field shall nevertheless be marginal.

WE-EF-207-01: FEATURED PRESENTATION and BEST IN PHYSICS (IMAGING): Task-Driven Imaging for Cone-Beam CT in Interventional Guidance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gang, G; Stayman, J; Ouadah, S

2015-06-15

Purpose: This work introduces a task-driven imaging framework that utilizes a patient-specific anatomical model, mathematical definition of the imaging task, and a model of the imaging system to prospectively design acquisition and reconstruction techniques that maximize task-based imaging performance. Utility of the framework is demonstrated in the joint optimization of tube current modulation and view-dependent reconstruction kernel in filtered-backprojection reconstruction and non-circular orbit design in model-based reconstruction. Methods: The system model is based on a cascaded systems analysis of cone-beam CT capable of predicting the spatially varying noise and resolution characteristics as a function of the anatomical model and amore » wide range of imaging parameters. Detectability index for a non-prewhitening observer model is used as the objective function in a task-driven optimization. The combination of tube current and reconstruction kernel modulation profiles were identified through an alternating optimization algorithm where tube current was updated analytically followed by a gradient-based optimization of reconstruction kernel. The non-circular orbit is first parameterized as a linear combination of bases functions and the coefficients were then optimized using an evolutionary algorithm. The task-driven strategy was compared with conventional acquisitions without modulation, using automatic exposure control, and in a circular orbit. Results: The task-driven strategy outperformed conventional techniques in all tasks investigated, improving the detectability of a spherical lesion detection task by an average of 50% in the interior of a pelvis phantom. The non-circular orbit design successfully mitigated photon starvation effects arising from a dense embolization coil in a head phantom, improving the conspicuity of an intracranial hemorrhage proximal to the coil. Conclusion: The task-driven imaging framework leverages a knowledge of the imaging task within a patient-specific anatomical model to optimize image acquisition and reconstruction techniques, thereby improving imaging performance beyond that achievable with conventional approaches. 2R01-CA-112163; R01-EB-017226; U01-EB-018758; Siemens Healthcare (Forcheim, Germany)« less

Gamma radiation effects on the dynamic fatigue measurements of glass discs

NASA Technical Reports Server (NTRS)

Ananaba, T. O. J.; Kinser, D. L.

1985-01-01

Circular specimens of low iron soda lime silicate glass were blasted with grit after having a circular notch etched into their centers. After separation into two groups, one group was exposed to gamma radiation. The fracture strengths of all samples were then tested by the biaxial technique, i.e., specimens were balanced on three balls and loaded in the center by a piston. The irradiated samples had received a 140,000 Gy dose from a Co-60 source. An enhanced interaction between the ambient moisture and the grit-blasted central notch was observed in the irradiated samples, which displayed accelerated corrosion.

Use of a synchronization card for XMCD measurements at the XMaS Beamline

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bouchenoire, L.; Brown, S. D.; Thompson, P. B. J.

X-ray Magnetic Circular Dichroism (XMCD) spectra from a 5 {mu}m polycrystalline Gd foil were measured in transmission across the Gd L{sub 2,3} edges using the Multipurpose Unit for Synchronisation, Sequencing and Triggering (MUSST) card developed at the European Synchrotron Radiation Facility (ESRF). The circularly polarized x-rays were produced by a diamond phase-plate and their helicity was rapidly reversed through the use of a piezo driven device. The signal measured for each helicity was recorded by the MUSST card synchronized to the helicity reversal. The results are compared to those obtained using an analogue lock-in technique.

An acoustic backscatter thermometer for remotely mapping seafloor water temperature

NASA Astrophysics Data System (ADS)

Jackson, Darrell R.; Dworski, J. George

1992-01-01

A bottom-mounted, circularly scanning sonar operating at 40 kHz has been used to map changes in water sound speed over a circular region 150 m in diameter. If it is assumed that the salinity remains constant, the change in sound speed can be converted to a change in temperature. For the present system, the spatial resolution is 7.5 m and the temperature resolution is 0.05°C. The technique is based on comparison of successive sonar scans by means of a correlation algorithm. The algorithm is illustrated using data from the Sediment Transport Events on Slopes and Shelves (STRESS) experiment.

Effect of pressure dependent viscosity on couple stress squeeze film lubrication between porous circular stepped plates

NASA Astrophysics Data System (ADS)

Hanumagowda, B. N.; Raju, B. T.; Santhosh Kumar, J.; Vasanth, K. R.

2018-04-01

In this paper, the effect of PDV on the couple stress squeeze film lubrication between porous circular stepped plates is presented. Keeping the base of Christensen’s stochastic theory modified Reynolds equation is derived. Reynolds equation, fluid film pressure, squeeze film time and load carrying capacity are solved using standard perturbation technique. The results are tabulated and presented graphically for selected physical parameters and found that the squeeze effect is depleted in a porous bearing compared to its nonporous and increasing permeability has an adverse effect on the pressure, load carrying capacity and time of approach.

Boundary layer separation on isolated boattail nozzles. M.S. Thesis; [conducted in the Langley 16-foot transonic wind tunnel

NASA Technical Reports Server (NTRS)

Abeyounis, W. K.

1977-01-01

The phenomenon of separated flow on a series of circular-arc afterbodies was investigated using the Langley 16-foot transonic tunnel at free-stream Mach numbers from 0.40 to 0.95 at 0 deg angle of attack. Both high-pressure air and solid circular cylinders with a diameter equal to the nozzle exit diameter were used to simulate jet exhausts. A detailed data base of boundary layer separation locations was obtained using oil-flow techniques. The results indicate that boundary layer separation is most extensive on steep boattails at high Mach numbers.

Detecting multiple outliers in linear functional relationship model for circular variables using clustering technique

NASA Astrophysics Data System (ADS)

Mokhtar, Nurkhairany Amyra; Zubairi, Yong Zulina; Hussin, Abdul Ghapor

2017-05-01

Outlier detection has been used extensively in data analysis to detect anomalous observation in data and has important application in fraud detection and robust analysis. In this paper, we propose a method in detecting multiple outliers for circular variables in linear functional relationship model. Using the residual values of the Caires and Wyatt model, we applied the hierarchical clustering procedure. With the use of tree diagram, we illustrate the graphical approach of the detection of outlier. A simulation study is done to verify the accuracy of the proposed method. Also, an illustration to a real data set is given to show its practical applicability.

The multi-mode polarization modulation spectrometer: part 1: simultaneous detection of absorption, turbidity, and optical activity.

PubMed

Arvinte, Tudor; Bui, Tam T T; Dahab, Ali A; Demeule, Barthélemy; Drake, Alex F; Elhag, Dhia; King, Peter

2004-09-01

Circular dichroism (CD) is an important spectroscopic technique for monitoring chirality and biological macromolecule conformation. However, during a CD measurement, absorbance, light scattering/turbidity, and fluorescence can also be detected. The simultaneous measurement of these different spectral features for a single sample is the basis of a multi-mode optical spectrometer. This allows time-efficient gathering of complementary information and provides a scheme to ensure that CD measurements are reliable. Aspects of circular polarization differential light scattering, pH, and temperature variation of a protein (antibody) solution are described. A procedure to help ensure that CD measurements are reliable is described.

Joint min-max distribution and Edwards-Anderson's order parameter of the circular 1/f-noise model

NASA Astrophysics Data System (ADS)

Cao, Xiangyu; Le Doussal, Pierre

2016-05-01

We calculate the joint min-max distribution and the Edwards-Anderson's order parameter for the circular model of 1/f-noise. Both quantities, as well as generalisations, are obtained exactly by combining the freezing-duality conjecture and Jack-polynomial techniques. Numerical checks come with significantly improved control of finite-size effects in the glassy phase, and the results convincingly validate the freezing-duality conjecture. Application to diffusive dynamics is discussed. We also provide a formula for the pre-factor ratio of the joint/marginal Carpentier-Le Doussal tail for minimum/maximum which applies to any logarithmic random energy model.

Use of a synchronization card for XMCD measurements at the XMaS Beamline

NASA Astrophysics Data System (ADS)

Bouchenoire, L.; Brown, S. D.; Thompson, P. B. J.; Hase, T. P. A.; Normile, P.; Bikondoa, O.; Hino, R.; Guijarro, M.; Stewart, M.; Cain, M. G.; Kervin, J.

2010-06-01

X-ray Magnetic Circular Dichroism (XMCD) spectra from a 5 μm polycrystalline Gd foil were measured in transmission across the Gd L2,3 edges using the Multipurpose Unit for Synchronisation, Sequencing and Triggering (MUSST) card developed at the European Synchrotron Radiation Facility (ESRF). The circularly polarized x-rays were produced by a diamond phase-plate and their helicity was rapidly reversed through the use of a piezo driven device. The signal measured for each helicity was recorded by the MUSST card synchronized to the helicity reversal. The results are compared to those obtained using an analogue lock-in technique.

Effects of elliptical burner geometry on partially premixed gas jet flames in quiescent surroundings

NASA Astrophysics Data System (ADS)

Baird, Benjamin

This study is the investigation of the effect of elliptical nozzle burner geometry and partial premixing, both 'passive control' methods, on a hydrogen/hydrocarbon flame. Both laminar and turbulent flames for circular, 3:1, and 4:1 aspect ratio (AR) elliptical burners are considered. The amount of air mixed with the fuel is varied from fuel-lean premixed flames to fuel-rich partially premixed flames. The work includes measurements of flame stability, global pollutant emissions, flame radiation, and flame structure for the differing burner types and fuel conditions. Special emphasis is placed on the near-burner region. Experimentally, both conventional (IR absorption, chemiluminecent, and polarographic emission analysis,) and advanced (laser induced fluorescence, planar laser induced fluorescence, Laser Doppler Velocimetry (LDV), Rayleigh scattering) diagnostic techniques are used. Numerically, simulations of 3-dimensional laminar and turbulent reacting flow are conducted. These simulations are run with reduced chemical kinetics and with a Reynolds Stress Model (RSM) for the turbulence modeling. It was found that the laminar flames were similar in appearance and overall flame length for the 3:1 AR elliptical and the circular burner. The laminar 4:1 AR elliptical burner flame split into two sub-flames along the burner major axis. This splitting had the effect of greatly shortening the 4:1 AR elliptical burner flame to have an overall flame length about half of that of the circular and 3:1 AR elliptical burner flames. The length of all three burners flames increased with increasing burner exit equivalence ratio. The blowout velocity for the three burners increased with increase in hydrogen mass fraction of the hydrogen/propane fuel mixture. For the rich premixed flames, the circular burner was the most stable, the 3:1 AR elliptical burner, was the least stable, and the 4:1 AR elliptical burner was intermediate to the two other burners. This order of stability was due to two reasons. The elliptical burners have enhanced turbulence generation that lowers their stability when compared to the circular burner. The 4:1 AR elliptical burner had greater stability due to a greater velocity decay rate and wider OH reaction zones particularly in the region between the two jets. The 3:1 AR elliptical and circular burners produced similar carbon monoxide and nitric oxide emission indexes over the range of equivalence ratios of 0.55 to 4.0, for laminar flames. (Abstract shortened by UMI.)

Chiral Plasmonic Nanostructures Fabricated by Circularly Polarized Light.

PubMed

Saito, Koichiro; Tatsuma, Tetsu

2018-05-09

The chirality of materials results in a wide variety of advanced technologies including image display, data storage, light management including negative refraction, and enantioselective catalysis and sensing. Here, we introduce chirality to plasmonic nanostructures by using circularly polarized light as the sole chiral source for the first time. Gold nanocuboids as precursors on a semiconductor were irradiated with circularly polarized light to localize electric fields at specific corners of the cuboids depending on the handedness of light and deposited dielectric moieties as electron oscillation boosters by the localized electric field. Thus, plasmonic nanostructures with high chirality were developed. The present bottom-up method would allow the large-scale and cost-effective fabrication of chiral materials and further applications to functional materials and devices.

78 FR 30328 - Announcement of National Geospatial Advisory Committee Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-22

... academic organizations, was established to advise the Federal Geographic Data Committee on management of... implementation of Office of Management and Budget (OMB) Circular A- 16. Topics to be addressed at the meeting include: Leadership Dialogue NSDI Strategic Plan Geospatial Platform OMB Circular A-16 Portfolio...

76 FR 77452 - Advisory Circular for Stall and Stick Pusher Training

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-13

... a recovery from a stall or approach. Scenario-based training that includes realistic events that... training, testing, and checking recommendations designed to maximize the likelihood that pilots will... circular was developed based on a review of recommended practices developed by major aircraft manufacturers...

Corrigendum to "Co-occurrence of linear and circular dichroism in chiral sculptured ZrO2 thin films" [Opt. Mater. 75 (January 2018) 319-324

NASA Astrophysics Data System (ADS)

Muhammad, Zahir; Wali, Faiz; Song, Li

2018-05-01

The authors regret .

A novel method for determining calibration and behavior of PVDF ultrasonic hydrophone probes in the frequency range up to 100 MHz.

PubMed

Bleeker, H J; Lewin, P A

2000-01-01

A new calibration technique for PVDF ultrasonic hydrophone probes is described. Current implementation of the technique allows determination of hydrophone frequency response between 2 and 100 MHz and is based on the comparison of theoretically predicted and experimentally determined pressure-time waveforms produced by a focused, circular source. The simulation model was derived from the time domain algorithm that solves the non linear KZK (Khokhlov-Zabolotskaya-Kuznetsov) equation describing acoustic wave propagation. The calibration technique data were experimentally verified using independent calibration procedures in the frequency range from 2 to 40 MHz using a combined time delay spectrometry and reciprocity approach or calibration data provided by the National Physical Laboratory (NPL), UK. The results of verification indicated good agreement between the results obtained using KZK and the above-mentioned independent calibration techniques from 2 to 40 MHz, with the maximum discrepancy of 18% at 30 MHz. The frequency responses obtained using different hydrophone designs, including several membrane and needle probes, are presented, and it is shown that the technique developed provides a desirable tool for independent verification of primary calibration techniques such as those based on optical interferometry. Fundamental limitations of the presented calibration method are also examined.

Advanced electromagnetic methods for aerospace vehicles

NASA Technical Reports Server (NTRS)

Balanis, Constantine A.; El-Sharawy, El-Budawy; Hashemi-Yeganeh, Shahrokh; Aberle, James T.; Birtcher, Craig R.

1991-01-01

The Advanced Helicopter Electromagnetics is centered on issues that advance technology related to helicopter electromagnetics. Progress was made on three major topics: composite materials; precipitation static corona discharge; and antenna technology. In composite materials, the research has focused on the measurements of their electrical properties, and the modeling of material discontinuities and their effect on the radiation pattern of antennas mounted on or near material surfaces. The electrical properties were used to model antenna performance when mounted on composite materials. Since helicopter platforms include several antenna systems at VHF and UHF bands, measuring techniques are being explored that can be used to measure the properties at these bands. The effort on corona discharge and precipitation static was directed toward the development of a new two dimensional Voltage Finite Difference Time Domain computer program. Results indicate the feasibility of using potentials for simulating electromagnetic problems in the cases where potentials become primary sources. In antenna technology the focus was on Polarization Diverse Conformal Microstrip Antennas, Cavity Backed Slot Antennas, and Varactor Tuned Circular Patch Antennas. Numerical codes were developed for the analysis of two probe fed rectangular and circular microstrip patch antennas fed by resistive and reactive power divider networks.

Binding of anti-prion agents to glycosaminoglycans: Evidence from electronic absorption and circular dichroism spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zsila, Ferenc; Gedeon, Gabor

2006-08-11

The polyanionic glycosaminoglycans (GAGs) are intimately involved in the pathogenesis of protein conformational disorders such as amyloidosis and prion diseases. Several cationic agents are known to exhibit anti-prion activity but their mechanism of action is poorly understood. In this study, UV absorption and circular dichroism (CD) spectroscopic techniques were used to investigate the interaction between heparin and chondroitin-6-sulfate and anti-prion drugs including acridine, quinoline, and phenothiazine derivatives. UV band hypochromism of ({+-})-quinacrine, ({+-})-primaquine, tacrine, quinidine, chlorpromazine, and induced CD spectra of ({+-})-quinacrine upon addition of GAGs provided evidence for the GAG binding of these compounds. The association constants ({approx}10{sup 6}-10{supmore » 7} M{sup -1}) estimated from the UV titration curves show high-affinity drug-heparin interactions. Ionic strength-dependence of the absorption spectra suggested that the interaction between GAGs and the cationic drugs is principally electrostatic in nature. Drug binding differences of heparin and chondroitin-6-sulfate were attributed to their different negative charge density. These results call the attention to the alteration of GAG-prion/GAG-amyloid interactions by which these compounds might exert their anti-prion/anti-amyloidogenic activities.« less

Identification of areas of recharge and discharge using Landsat-TM satellite imagery and aerial photography mapping techniques

NASA Astrophysics Data System (ADS)

Salama, R. B.; Tapley, I.; Ishii, T.; Hawkes, G.

1994-10-01

Aerial photographs (AP) and Landsat (TM) colour composites were used to map the geomorphology, geology and structures of the Salt River System of Western Australia. Geomorphic features identified are sand plains, dissected etchplain, colluvium, lateritic duricrust and rock outcrops. The hydrogeomorphic units include streams, lakes and playas, palaeochannels and palaeodeltas. The structural features are linear and curvilinear lineaments, ring structures and dolerite dykes. Suture lines control the course of the main river channel. Permeable areas around the circular granitic plutons were found to be the main areas of recharge in the uplands. Recharge was also found to occur in the highly permeable areas of the sandplains. Discharge was shown to be primarily along the main drainage lines, on the edge of the circular sandplains, in depressions and in lakes. The groundwater occurrence and hydrogeological classification of the recharge potential of the different units were used to classify the mapped areas into recharge and discharge zones. The results also show that TM colour composites provide a viable source of data comparable with AP for mapping and delineating areas of recharge and discharge on a regional scale.

Geometry modeling of single track cladding deposited by high power diode laser with rectangular beam spot

NASA Astrophysics Data System (ADS)

Liu, Huaming; Qin, Xunpeng; Huang, Song; Hu, Zeqi; Ni, Mao

2018-01-01

This paper presents an investigation on the relationship between the process parameters and geometrical characteristics of the sectional profile for the single track cladding (STC) deposited by High Power Diode Laser (HPDL) with rectangle beam spot (RBS). To obtain the geometry parameters, namely cladding width Wc and height Hc of the sectional profile, a full factorial design (FFD) of experiment was used to conduct the experiments with a total of 27. The pre-placed powder technique has been employed during laser cladding. The influence of the process parameters including laser power, powder thickness and scanning speed on the Wc and Hc was analyzed in detail. A nonlinear fitting model was used to fit the relationship between the process parameters and geometry parameters. And a circular arc was adopted to describe the geometry profile of the cross-section of STC. The above models were confirmed by all the experiments. The results indicated that the geometrical characteristics of the sectional profile of STC can be described as the circular arc, and the other geometry parameters of the sectional profile can be calculated only using Wc and Hc. Meanwhile, the Wc and Hc can be predicted through the process parameters.

Developing integrated methods to address complex resource and environmental issues

USGS Publications Warehouse

Smith, Kathleen S.; Phillips, Jeffrey D.; McCafferty, Anne E.; Clark, Roger N.

2016-02-08

IntroductionThis circular provides an overview of selected activities that were conducted within the U.S. Geological Survey (USGS) Integrated Methods Development Project, an interdisciplinary project designed to develop new tools and conduct innovative research requiring integration of geologic, geophysical, geochemical, and remote-sensing expertise. The project was supported by the USGS Mineral Resources Program, and its products and acquired capabilities have broad applications to missions throughout the USGS and beyond.In addressing challenges associated with understanding the location, quantity, and quality of mineral resources, and in investigating the potential environmental consequences of resource development, a number of field and laboratory capabilities and interpretative methodologies evolved from the project that have applications to traditional resource studies as well as to studies related to ecosystem health, human health, disaster and hazard assessment, and planetary science. New or improved tools and research findings developed within the project have been applied to other projects and activities. Specifically, geophysical equipment and techniques have been applied to a variety of traditional and nontraditional mineral- and energy-resource studies, military applications, environmental investigations, and applied research activities that involve climate change, mapping techniques, and monitoring capabilities. Diverse applied geochemistry activities provide a process-level understanding of the mobility, chemical speciation, and bioavailability of elements, particularly metals and metalloids, in a variety of environmental settings. Imaging spectroscopy capabilities maintained and developed within the project have been applied to traditional resource studies as well as to studies related to ecosystem health, human health, disaster assessment, and planetary science. Brief descriptions of capabilities and laboratory facilities and summaries of some applications of project products and research findings are included in this circular. The work helped support the USGS mission to “provide reliable scientific information to describe and understand the Earth; minimize loss of life and property from natural disasters; manage water, biological, energy, and mineral resources; and enhance and protect our quality of life.” Activities within the project include the following:Spanned scales from microscopic to planetary;Demonstrated broad applications across disciplines;Included life-cycle studies of mineral resources;Incorporated specialized areas of expertise in applied geochemistry including mineralogy, hydrogeology, analytical chemistry, aqueous geochemistry, biogeochemistry, microbiology, aquatic toxicology, and public health; andIncorporated specialized areas of expertise in geophysics including magnetics, gravity, radiometrics, electromagnetics, seismic, ground-penetrating radar, borehole radar, and imaging spectroscopy.This circular consists of eight sections that contain summaries of various activities under the project. The eight sections are listed below:Laboratory Facilities and Capabilities, which includes brief descriptions of the various types of laboratories and capabilities used for the project;Method and Software Development, which includes summaries of remote-sensing, geophysical, and mineralogical methods developed or enhanced by the project;Instrument Development, which includes descriptions of geophysical instruments developed under the project;Minerals, Energy, and Climate, which includes summaries of research that applies to mineral or energy resources, environmental processes and monitoring, and carbon sequestration by earth materials;Element Cycling, Toxicity, and Health, which includes summaries of several process-oriented geochemical and biogeochemical studies and health-related research activities;Hydrogeology and Water Quality, which includes descriptions of innovative geophysical, remote-sensing, and geochemical research pertaining to hydrogeology and water-quality applications;Hazards and Disaster Assessment, which includes summaries of research and method development that were applied to natural hazards, human-caused hazards, and disaster assessments; andDatabases and Framework Studies, which includes descriptions of fundamental applications of geophysical studies and of the importance of archived data.

Improving Vortex Generators to Enhance the Performance of Air-Cooled Condensers in a Geothermal Power Plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Manohar S. Sohal

2005-09-01

This report summarizes work at the Idaho National Laboratory to develop strategies to enhance air-side heat transfer in geothermal air-cooled condensers such that it should not significantly increase pressure drop and parasitic fan pumping power. The work was sponsored by the U.S. Department of Energy, NEDO (New Energy and Industrial Technology Development Organization) of Japan, Yokohama National University, and the Indian Institute of Technology, Kanpur, India. A combined experimental and numerical investigation was performed to investigate heat transfer enhancement techniques that may be applicable to largescale air-cooled condensers such as those used in geothermal power applications. A transient heat transfermore » visualization and measurement technique was employed in order to obtain detailed distributions of local heat transfer coefficients on model fin surfaces. Pressure drop measurements were obtained for a variety of tube and winglet configurations using a single-channel flow apparatus that included four tube rows in a staggered array. Heat transfer and pressure drop measurements were also acquired in a separate multiple-tube row apparatus in the Single Blow Test Facility. In addition, a numerical modeling technique was developed to predict local and average heat transfer for these low-Reynolds number flows, with and without winglets. Representative experimental and numerical results were obtained that reveal quantitative details of local finsurface heat transfer in the vicinity of a circular tube with a single delta winglet pair downstream of the cylinder. Heat transfer and pressure-drop results were obtained for flow Reynolds numbers based on channel height and mean flow velocity ranging from 700 to 6500. The winglets were of triangular (delta) shape with a 1:2 or 1:3 height/length aspect ratio and a height equal to 90% of the channel height. Overall mean fin-surface heat transfer results indicate a significant level of heat transfer enhancement (in terms of Colburn j-factor) associated with deployment of the winglets with circular as well as oval tubes. In general, toe-in (common flow up) type winglets appear to have better performance than the toe-out (common flow down) type winglets. Comparisons of heat transfer and pressure drop results for the elliptical tube versus a circular tube with and without winglets are provided. During the course of their independent research, all of the researchers have established that about 10 to 30% enhancement in Colburn j-factor is expected. However, actual increase in heat transfer rate from a heat exchanger employing finned tubes with winglets may be smaller, perhaps on the order of 2 to 5%. It is also concluded that for any specific application, more full-size experimentation is needed to optimize the winglet design for a specific heat exchanger application. If in place of a circular tube, an oval tube can be economically used in a bundle, it is expected that the pressure drop across the tube bundle with the application of vortex generators (winglets) will be similar to that in a conventional circular tube bundle. It is hoped that the results of this research will demonstrate the benefits of applying vortex generators (winglets) on the fins to improve the heat transfer from the air-side of the tube bundle.« less

Method for testing the strength and structural integrity of nuclear fuel particles

DOEpatents

Lessing, P.A.

1995-10-17

An accurate method for testing the strength of nuclear fuel particles is disclosed. Each particle includes an upper and lower portion, and is placed within a testing apparatus having upper and lower compression members. The upper compression member includes a depression therein which is circular and sized to receive only part of the upper portion of the particle. The lower compression member also includes a similar depression. The compression members are parallel to each other with the depressions therein being axially aligned. The fuel particle is then placed between the compression members and engaged within the depressions. The particle is then compressed between the compression members until it fractures. The amount of force needed to fracture the particle is thereafter recorded. This technique allows a broader distribution of forces and provides more accurate results compared with systems which distribute forces at singular points on the particle. 13 figs.

Method for testing the strength and structural integrity of nuclear fuel particles

DOEpatents

Lessing, Paul A.

1995-01-01

An accurate method for testing the strength of nuclear fuel particles. Each particle includes an upper and lower portion, and is placed within a testing apparatus having upper and lower compression members. The upper compression member includes a depression therein which is circular and sized to receive only part of the upper portion of the particle. The lower compression member also includes a similar depression. The compression members are parallel to each other with the depressions therein being axially aligned. The fuel particle is then placed between the compression members and engaged within the depressions. The particle is then compressed between the compression members until it fractures. The amount of force needed to fracture the particle is thereafter recorded. This technique allows a broader distribution of forces and provides more accurate results compared with systems which distribute forces at singular points on the particle.

Cup Cylindrical Waveguide Antenna

NASA Technical Reports Server (NTRS)

Acosta, Roberto J.; Darby, William G.; Kory, Carol L.; Lambert, Kevin M.; Breen, Daniel P.

2008-01-01

The cup cylindrical waveguide antenna (CCWA) is a short backfire microwave antenna capable of simultaneously supporting the transmission or reception of two distinct signals having opposite circular polarizations. Short backfire antennas are widely used in mobile/satellite communications, tracking, telemetry, and wireless local area networks because of their compactness and excellent radiation characteristics. A typical prior short backfire antenna contains a half-wavelength dipole excitation element for linear polarization or crossed half-wavelength dipole elements for circular polarization. In order to achieve simultaneous dual circular polarization, it would be necessary to integrate, into the antenna feed structure, a network of hybrid components, which would introduce significant losses. The CCWA embodies an alternate approach that entails relatively low losses and affords the additional advantage of compactness. The CCWA includes a circular cylindrical cup, a circular disk subreflector, and a circular waveguide that serves as the excitation element. The components that make it possible to obtain simultaneous dual circular polarization are integrated into the circular waveguide. These components are a sixpost polarizer and an orthomode transducer (OMT) with two orthogonal coaxial ports. The overall length of the OMT and polarizer (for the nominal middle design frequency of 2.25 GHz) is about 11 in. (approximately equal to 28 cm), whereas the length of a commercially available OMT and polarizer for the same frequency is about 32 in. (approximately equal to 81 cm).

A circularly polarized optical dipole trap and other developments in laser trapping of atoms

NASA Astrophysics Data System (ADS)

Corwin, Kristan Lee

Several innovations in laser trapping and cooling of alkali atoms are described. These topics share a common motivation to develop techniques for efficiently manipulating cold atoms. Such advances facilitate sensitive precision measurements such as parity non- conservation and 8-decay asymmetry in large trapped samples, even when only small quantities of the desired species are available. First, a cold, bright beam of Rb atoms is extracted from a magneto-optical trap (MOT) using a very simple technique. This beam has a flux of 5 × 109 atoms/s and a velocity of 14 m/s, and up to 70% of the atoms in the MOT were transferred to the atomic beam. Next, a highly efficient MOT for radioactive atoms is described, in which more than 50% of 221Fr atoms contained in a vapor cell are loaded into a MOT. Measurements were also made of the 221Fr 7 2P1/2 and 7 2P3/2 energies and hyperfine constants. To perform these experiments, two schemes for stabilizing the frequency of the light from a diode laser were developed and are described in detail. Finally, a new type of trap is described and a powerful cooling technique is demonstrated. The circularly polarized optical dipole trap provides large samples of highly spin-polarized atoms, suitable for many applications. Physical processes that govern the transfer of large numbers of atoms into the trap are described, and spin-polarization is measured to be 98(1)%. In addition, the trap breaks the degeneracy of the atomic spin states much like a magnetic trap does. This allows for RF and microwave cooling via both forced evaporation and a Sisyphus mechanism. Preliminary application of these techniques to the atoms in the circularly polarized dipole trap has successfully decreased the temperature by a factor of 4 while simultaneously increasing phase space density.

Do Galactic Potential Wells Depend on Their Largescale Environment

NASA Astrophysics Data System (ADS)

Mo, H. J.; Lahav, O.

1993-04-01

We study the dependence of the intrinsic velocities of galaxies on their large-scale environment, using a cross-correlation technique that provides an objective way of defining the local overdensity of `trace' galaxies around `target' galaxies. We use galaxies in optical (CfA and SSRS) and IRAS redshift surveys as tracers of the density field, and about 1000 spiral galaxies with measured circular velocities and elliptical galaxies with measured velocity dispersion as `targets'. We find that the correlation function tends to increase with circular velocity, the trend being weak except in the case of cD-like elliptical galaxies with the highest velocity dispersions (σ >~ 300 km s^-1^), where the effect is strong, possibly due to morphological segregations in clusters of galaxies. A fit to the mean overdensity δ(r < r_p_) of the trace galaxies (in spheres of radius r_p_) around target galaxies as a function of the circular velocities V_c_ shows a weak increase of δ with v_c_, with slope {DELTA}δ(r<~3.6 h^-1^ Mpc)/{DELTA}V_c_ <~ 0.02. The observed weak correlation is contrasted with the strong dependence of the correlation functions of dark haloes on their circular velocities predicted in some (e.g. high-biasing cold dark matter) models for galaxy formation. In particular, our results are inconsistent with the prediction of the `natural' (high) biasing model at a high significance level. Comparison of our results with those of a simple biasing model suggests that either the observed circular velocities of galaxies are not simply related to the circular velocities of dark haloes, or most dark haloes were formed at high redshifts, or the galaxy distribution does not trace the matter distribution in a simple way.

Extended High Circular Polarization in the Orion Massive Star Forming Region: Implications for the Origin of Homochirality in the Solar System

PubMed Central

Tamura, Motohide; Kandori, Ryo; Kusakabe, Nobuhiko; Hough, James H.; Bailey, Jeremy; Whittet, Douglas C. B.; Lucas, Philip W.; Nakajima, Yasushi; Hashimoto, Jun

2010-01-01

We present a wide-field (∼6′ × 6′) and deep near-infrared (Ks band: 2.14 μm) circular polarization image in the Orion nebula, where massive stars and many low-mass stars are forming. Our results reveal that a high circular polarization region is spatially extended (∼0.4 pc) around the massive star-forming region, the BN/KL nebula. However, other regions, including the linearly polarized Orion bar, show no significant circular polarization. Most of the low-mass young stars do not show detectable extended structure in either linear or circular polarization, in contrast to the BN/KL nebula. If our solar system formed in a massive star-forming region and was irradiated by net circularly polarized radiation, then enantiomeric excesses could have been induced, through asymmetric photochemistry, in the parent bodies of the meteorites and subsequently delivered to Earth. These could then have played a role in the development of biological homochirality on Earth. PMID:20213160

Three-dimensional structural imaging of starch granules by second-harmonic generation circular dichroism.

PubMed

Zhuo, G-Y; Lee, H; Hsu, K-J; Huttunen, M J; Kauranen, M; Lin, Y-Y; Chu, S-W

2014-03-01

Chirality is one of the most fundamental and essential structural properties of biological molecules. Many important biological molecules including amino acids and polysaccharides are intrinsically chiral. Conventionally, chiral species can be distinguished by interaction with circularly polarized light, and circular dichroism is one of the best-known approaches for chirality detection. As a linear optical process, circular dichroism suffers from very low signal contrast and lack of spatial resolution in the axial direction. It has been demonstrated that by incorporating nonlinear interaction with circularly polarized excitation, second-harmonic generation circular dichroism can provide much higher signal contrast. However, previous circular dichroism and second-harmonic generation circular dichroism studies are mostly limited to probe chiralities at surfaces and interfaces. It is known that second-harmonic generation, as a second-order nonlinear optical effect, provides excellent optical sectioning capability when combined with a laser-scanning microscope. In this work, we combine the axial resolving power of second-harmonic generation and chiral sensitivity of second-harmonic generation circular dichroism to realize three-dimensional chiral detection in biological tissues. Within the point spread function of a tight focus, second-harmonic generation circular dichroism could arise from the macroscopic supramolecular packing as well as the microscopic intramolecular chirality, so our aim is to clarify the origins of second-harmonic generation circular dichroism response in complicated three-dimensional biological systems. The sample we use is starch granules whose second-harmonic generation-active molecules are amylopectin with both microscopic chirality due to its helical structure and macroscopic chirality due to its crystallized packing. We found that in a starch granule, the second-harmonic generation for right-handed circularly polarized excitation is significantly different from second-harmonic generation for left-handed one, offering excellent second-harmonic generation circular dichroism contrast that approaches 100%. In addition, three-dimensional visualization of second-harmonic generation circular dichroism distribution with sub-micrometer spatial resolution is realized. We observed second-harmonic generation circular dichroism sign change across the starch granules, and the result suggests that in thick biological tissue, second-harmonic generation circular dichroism arises from macroscopic molecular packing. Our result provides a new method to visualize the organization of three-dimensional structures of starch granules. The second-harmonic generation circular dichroism imaging method expands the horizon of nonlinear chiroptical studies from simplified surface/solution environments to complicated biological tissues. © 2014 The Authors Journal of Microscopy © 2014 Royal Microscopical Society.

Synthesis of multiple shaped beam antenna patterns

NASA Technical Reports Server (NTRS)

Stutzman, W. L.; Coffey, E. L.

1973-01-01

Results are presented of research into the problem of finding an excitation of a given antenna such that the desired radiation pattern is approximated to within acceptable limits. This is to be done in such a fashion that boundary conditions involving hardware limitations may be inserted into the problem. The intended application is synthesis of multiple shaped beam antennas. Since this is perhaps the most difficult synthesis problem an antenna engineer is likely to encounter, the approach taken was to include as a by-product capability for synthesizing simpler patterns. The synthesis technique has been almost totally computerized. The class of antennas which may be synthesized with the computer program are those which may be represented as planar (continuous or discrete) current distributions. The technique is not limited in this sense and could indeed by extended to include, for example, the synthesis of conformal arrays or current distributions on the surface of reflectors. The antenna types which the program is set up to synthesize are: line source, rectangular aperture, circular aperture, linear array, rectangular array, and arbitrary planar array.

Double-injection, deep-impurity switch development

NASA Technical Reports Server (NTRS)

Whitson, D. W.

1985-01-01

The overall objective of this program was the development of device design and process techniques for the fabrication of a double-injection, deep-impurity (DI) sup 2 silicon switch that operates in the 2-10 kV range with conduction current values of 5 A at 2 kV and 1 A at 10 kV. Other major specifications include a holding voltage of 10 V with no gate current, 10 microsec switching time, and power dissipation of 50 W at 75 C. It was decided to concentrate on the lateral circular devices in order to optimize the gold diffusion. This resulted in devices that are much better switches (approx.1 micro sec switching time), and in a gold diffusion process that is much more controllable than those previously developed. Some results with injection-gated devices were also obtained. The current conduction for V less than VT was analyzed and seen to agree, for the most part, with Lampert's theory. Various sections of this report describe the device designs, wafer-processing techniques, and various measurements which include ac and dc characteristics and four-point probe.

78 FR 60167 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-70; Introduction

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-30

...)(3), contracting officers are encouraged to include the changes in these rules in major modifications.... William Clark, Acting Director, Office of Government-wide Acquisition Policy, Office of Acquisition Policy, Office of Government-wide Policy. Federal Acquisition Circular (FAC) 2005-70 is issued under the...

Information for Handicapped Travelers. Reference Circular No. 87-3.

ERIC Educational Resources Information Center

Nussbaum, Ruth, Comp.

This circular provides information about travel agencies, travel information centers, and transportation services based on descriptive literature provided by companies and organizations that offer services to handicapped travelers; access guides to specific cities and tourist sites are not included. The first section lists books on travel for the…

Management of Federal Information Resources. Circular No. A-130.

ERIC Educational Resources Information Center

Office of Management and Budget, Washington, DC.

Directed to the heads of executive departments and establishments, this circular establishes policy for the management of federal information resources. Procedural and analytic guidelines for implemented aspects of these policies are included as appendices. The policies apply to the information activities of all agencies of the executive branch of…

78 FR 60174 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-70; Small Entity Compliance Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-30

... DEPARTMENT OF DEFENSE GENERAL SERVICES ADMINISTRATION NATIONAL AERONAUTICS AND SPACE... Acquisition Circular 2005-70; Small Entity Compliance Guide AGENCY: Department of Defense (DoD), General... employees at subpart 3.9. In accordance with FAR 1.108(d)(3), contracting officers are encouraged to include...

Deaf-Blindness: National Organizations and Resources. Reference Circular No. 93-1.

ERIC Educational Resources Information Center

Library of Congress, Washington, DC. National Library Service for the Blind and Physically Handicapped.

This circular lists national organizations and print and audiovisual resources on areas of service to persons with deaf blindness, including rehabilitation, education, information and referral, recreation, and sources for adaptive devices and products. Section I is an alphabetical list of 40 national organizations and resources, including…

Cinematique et dynamique des galaxies spirales barrees

NASA Astrophysics Data System (ADS)

Hernandez, Olivier

The total mass (luminous and dark) of galaxies is derived from their circular velocities. Spectroscopic Fabry-Perot observations of the ionized gas component of spiral galaxies allow one to derive their kinematics. In the case of purely axisymmetric velocity fields--as in non-active and unbarred spirals galaxies-- the circular velocities can be derived directly. However, the velocity fields of barred galaxies (which constitute two thirds of the spirals) exhibit strong non-circular motions and need a careful analysis to retrieve the circular component. This thesis proposes the necessary steps to recover the axisymmetric component of barred spiral galaxies. The first step was to develop the best instrumentation possible for this work. [Special characters omitted.] , which is the most sensitive photon counting camera ever developed, was coupled to a Fabry-Perot interferometer. The observations of a sample of barred spiral galaxies--the BH a BAR sample--was assembled in order to obtain the most rigourous velocity fields. Then, the Tremaine-Weinberg method, which can determine the bar pattern speed and is usually used with the observations of stellar component, has been tested on the ionised gas and gave satisfactory results. Finally, all the above techniques have been applied to the BH a BAR sample in order to study the key parameters of the galaxies' evolution--bar pattern speeds, multiple stationary waves, resonances etc.--which will allow one to use N-body+SPH simulations to model properly the non-circular motions and determine the true total mass of barred spiral galaxies.

Remote Sensing as a First Step in Geothermal Exploration in the Xilingol Volcanic Field in NE China

NASA Astrophysics Data System (ADS)

Peng, F.; Huang, S.; Xiong, Y.

2013-12-01

Geothermal energy is a renewable and low-carbon energy source independent of climate change. It is most abundant in Cenozoic volcanic areas where high temperature can be obtained within a relatively shallow depth. Geological structures play an important role in the transfer and storage of geothermal energy. Like other geological resources, geothermal resource prospecting and exploration require a good understanding of the host media. Remote sensing (RS) has the advantages of high spatial and temporal resolution and broad spatial coverage over the conventional geological and geophysical prospecting techniques, while geographical information system (GIS) has intuitive, flexible, and convenient characteristics. In this study, RS and GIS techniques are utilized to prospect the geothermal energy potential in Xilingol, a Cenozoic volcanic area in the eastern Inner Mongolia, NE China. Landsat TM/ETM+ multi-temporal images taken under clear-sky conditions, digital elevation model (DEM) data, and other auxiliary data including geological maps of 1:2,500,000 and 1:200,000 scales are used in this study. The land surface temperature (LST) of the study area is retrieved from the Landsat images with a single-channel algorithm. Prior to the LST retrieval, the imagery data are preprocessed to eliminate abnormal values by reference to the normalized difference vegetation index (NDVI) and the improved normalized water index (MNDWI) on the ENVI platform developed by ITT Visual Information Solutions. Linear and circular geological structures are then inferred through visual interpretation of the LST maps with references to the existing geological maps in conjunction with the computer automatic interpretation features such as lineament frequency, lineament density, and lineament intersection. Several useful techniques such as principal component analysis (PCA), image classification, vegetation suppression, multi-temporal comparative analysis, and 3D Surface View based on DEM data are used to further enable a better visual geologic interpretation with the Landsat imagery of Xilingol. Several major volcanism controlling faults and Cenozoic volcanic eruption centers have been recognized from the linear and circular structures in the remote sensing images. The result shows that the major faults in the study area are mainly NEE oriented. Hidden faults and deep structures are inferred from the analysis of distribution regularities of linear and circular structures. Especially, the swarms of craters northwest to the Dalinuoer Lake appear to be controlled by some NEE trending hidden basement fractures. The intersecting areas of the NEE linear structures with NW trending structures overlapped by the circular structures are the favorable regions for geothermal resources. Seven areas have been preliminarily identified as the targets for further prospecting geothermal energy based on the visual interpretation of the geological structures. The study shows that RS and GIS have great application potential in the geothermal exploration in volcanic areas and will promote the exploration of renewable energy resources of great potential.

Design of three-dimensional scramjet inlets for hypersonic propulsion

NASA Technical Reports Server (NTRS)

Simmons, J. M.; Weidner, E. H.

1986-01-01

The paper outlines an approach to the design of three-dimensional inlets for scramjet engines. The basis of the techniques used is the method of streamline tracing through an inviscid axisymmetric flow field. A technique is described for making a smooth change of cross-section shape from rectangular to circular. A feature is the considerable use of computer-graphics to provide a 'user-oriented' procedure which can produce promising design configurations for subsequent analysis with CFD codes. An example is given to demonstrate the capabilities of the design techniques.

Space debris, asteroids and satellite orbits; Proceedings of the Fourth and Thirteenth Workshops, Graz, Austria, June 25-July 7, 1984

NASA Technical Reports Server (NTRS)

Kessler, D. J.; Gruen, E.; Sehnal, L.

1985-01-01

The workshops covered a variety of topics relevant to the identification, characterization and monitoring of near-earth solar system debris. Attention was given to man-made and naturally occurring microparticles, their hazards to present and future spacecraft, and ground- and space-based techniques for tracking both large and small debris. The studies are extended to solid fuel particulates in circular space. Asteroid rendezvous missions are discussed, including propulsion and instrumentation options, the possibility of encountering asteroids during Hohman transfer flights to Venus and/or Mars, and the benefits of multiple encounters by one spacecraft. Finally, equipment and analytical models for generating precise satellite orbits are reviewed.

Modelling of Folding Patterns in Flat Membranes and Cylinders by Origami

NASA Astrophysics Data System (ADS)

Nojima, Taketoshi

This paper describes folding methods of thin flat sheets as well as cylindrical shells by modelling folding patterns through Japanese traditional Origami technique. New folding patterns have been devised in thin flat squared or circular membrane by modifying so called Miura-Ori in Japan (one node with 4 folding lines). Some folding patterns in cylindrical shells have newly been developed including spiral configurations. Devised foldable cylindrical shells were made by using polymer sheets, and it has been assured that they can be folded quite well. The devised models will make it possible to construct foldable/deployable space structures as well as to manufacture foldable industrial products and living goods, e. g., bottles for soft drinks.

Interaction Between a Steady Detonation Wave in Nitromethane and Geometrical Complex Confinement Defects

NASA Astrophysics Data System (ADS)

Crouzet, B.; Soulard, L.; Carion, N.; Manczur, P.

2007-12-01

Two copper cylinder expansion tests were carried out on nitromethane. They differ from the classical cylinder test in that the liner includes evenly-spaced protruding circular defects. The aim is to study how a detonation front propagating in the liquid explosive interacts with the confining material defects. The subsequent motion of the metal, accelerated by the expanding detonation products, is measured using a range of diagnostic techniques: electrical probes, a rapid framing camera, a glass block associated with a streak camera and velocity laser interferometers. The different experimental records have been examined in the light of previous classical cylinder test measurements, simple 2D theoretical shock polar analysis results and 2D numerical simulations.

Crater dimensions from apollo data and supplemental sources

USGS Publications Warehouse

Pike, R.J.

1976-01-01

A catalog of crater dimensions that were compiled mostly from the new Apollo-based Lunar Topographic Orthophotomaps is presented in its entirety. Values of crater diameter, depth, rim height, flank width, circularity, and floor diameter (where applicable) are tabulated for a sample of 484 craters on the Moon and 22 craters on Earth. Systematic techniques of mensuration are detailed. The lunar craters range in size from 400 m to 300 km across and include primary impact craters of the main sequence, secondary impact craters, craterlets atop domes and cones, and dark-halo craters. The terrestrial craters are between 10 m and 22.5 km in diameter and were formed by meteorite impact. ?? 1976 D. Reidel Publishing Company.

Fitting and Reconstruction of Thirteen Simple Coronal Mass Ejections

NASA Astrophysics Data System (ADS)

Al-Haddad, Nada; Nieves-Chinchilla, Teresa; Savani, Neel P.; Lugaz, Noé; Roussev, Ilia I.

2018-05-01

Coronal mass ejections (CMEs) are the main drivers of geomagnetic disturbances, but the effects of their interaction with Earth's magnetic field depend on their magnetic configuration and orientation. Fitting and reconstruction techniques have been developed to determine important geometrical and physical CME properties, such as the orientation of the CME axis, the CME size, and its magnetic flux. In many instances, there is disagreement between different methods but also between fitting from in situ measurements and reconstruction based on remote imaging. This could be due to the geometrical or physical assumptions of the models, but also to the fact that the magnetic field inside CMEs is only measured at one point in space as the CME passes over a spacecraft. In this article we compare three methods that are based on different assumptions for measurements by the Wind spacecraft for 13 CMEs from 1997 to 2015. These CMEs are selected from the interplanetary coronal mass ejections catalog on https://wind.nasa.gov/ICMEindex.php because of their simplicity in terms of: 1) slow expansion speed throughout the CME and 2) weak asymmetry in the magnetic field profile. This makes these 13 events ideal candidates for comparing codes that do not include expansion or distortion. We find that for these simple events, the codes are in relatively good agreement in terms of the CME axis orientation for six of the 13 events. Using the Grad-Shafranov technique, we can determine the shape of the cross-section, which is assumed to be circular for the other two models, a force-free fitting and a circular-cylindrical non force-free fitting. Five of the events are found to have a clear circular cross-section, even when this is not a precondition of the reconstruction. We make an initial attempt at evaluating the adequacy of the different assumptions for these simple CMEs. The conclusion of this work strongly suggests that attempts at reconciling in situ and remote-sensing views of CMEs must take into consideration the compatibility of the different models with specific CME structures to better reproduce flux ropes.

Laser Stimulated Thermoluminescence

NASA Astrophysics Data System (ADS)

Abtahi, Abdollah

Techniques for localized heating of semi-infinite single-layer and two-layer structures are investigated theoretically and experimentally, motivated by applications in thermoluminescence (TL) dosimetry of ionizing radiation. The heat-conduction equations are solved by the Green's function technique to obtain the transient temperature distribution caused by exposure to laser beams of Gaussian and uniform circular intensity profiles. It is shown that the spatio-temporal temperature response is readily monitored by the TL response that results when layer configuration contains a thermoluminescent phosphor. The experiments for the verification of the developed theory are performed with two specially constructed TL detection systems, one featuring a laser beam of Gaussian profile and the other a uniform circular laser beam. Measurements of the thermoluminescent emission from a number of different TL systems are performed and compared with computed responses on the basis of simple electron kinetics. We experiment exclusively with the commercial TL phosphor LiF:Mg,Ti(TLD-100, Harshaw), the most widely used material in thermoluminescence dosimetry. We study in detail localized Gaussian beam heating of it in the form of 0.9 mm thick slabs, self-supporting firms of fine-grain powder in a polyimide (Kapton) matrix, and on substrates of LiF single crystals or borosilicate glass. Thermoluminescent layers on glass substrates have been heated with Gaussian and uniform circular intensity profiles in two different modes: the laser beam impinges onto (a) the phosphor layer, and (b) the glass substrate. It is demonstrated that the optical and thermal behavior of the dosimeters can be determined by these methods and that, furthermore, the thermoluminescence response of a given configuration can be simulated as a function of a number of experimental parameters such as laser power, beam size, substrate and TL-layer thicknesses, and configuration of the dosimeters. In addition, we have investigated the dependence of the luminous efficiency (normalized thermoluminescence yield) and peak heights on heating rates in the range from 4 K/s to 5500 K/s. The efficiency values obtained are then included in the comparison of experimental and theoretical TL responses curves for various laser powers.

Global Search of a Three-dimensional Low Solidity Circular Cascade Diffuser for Centrifugal Blowers by Meta-model Assisted Optimization

NASA Astrophysics Data System (ADS)

Sakaguchi, Daisaku; Sakue, Daiki; Tun, Min Thaw

2018-04-01

A three-dimensional blade of a low solidity circular cascade diffuser in centrifugal blowers is designed by means of a multi-point optimization technique. The optimization aims at improving static pressure coefficient at a design point and at a small flow rate condition. Moreover, a clear definition of secondary flow expressed by positive radial velocity at hub side is taken into consideration in constraints. The number of design parameters for three-dimensional blade reaches to 10 in this study, such as a radial gap, a radial chord length and mean camber angle distribution of the LSD blade with five control points, control point between hub and shroud with two design freedom. Optimization results show clear Pareto front and selected optimum design shows good improvement of pressure rise in diffuser at small flow rate conditions. It is found that three-dimensional blade has advantage to stabilize the secondary flow effect with improving pressure recovery of the low solidity circular cascade diffuser.

Design and operation of small biogas plants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abdel-Dayem, A.M.; Hamad, M.A.

1980-12-01

This paper concentrates on the experience gained from the adaptation of the Chinese biogas technology to rural areas of Egypt. Three different prototype digesters have been constructed. The first is a 10 M/sup 3/ rectangular digester of the water pressure type, the second is a 6 M/sup 3/ circular and shallow digester with domed roof and dished bottom. The third prototype unit with a capacity of 7 M/sup 3/ has been recently constructed. It combines the features of both plug flow and the Indian movable cap types. Provisions for solar heating of feed water, composting of effluent and attachments tomore » both latrine and animal shed were incorporated in the unit. The structural theory, design criteria, construction technique and cost estimation of the circular digester are described. Some operation and performance data of the circular digester are presented. This covers the effects of variation of ambient temperature on internal temperature, effects of temperature and pressure on the gas production rate and composition.« less

Circular RNA - New member of noncoding RNA with novel functions.

PubMed

Hsiao, Kuei-Yang; Sun, H Sunny; Tsai, Shaw-Jenq

2017-06-01

A growing body of evidence indicates that circular RNAs are not simply a side product of splicing but a new class of noncoding RNAs in higher eukaryotes. The progression for the studies of circular RNAs is accelerated by combination of several advanced technologies such as next generation sequencing, gene silencing (small interfering RNAs) and editing (CRISPR/Cas9). More and more studies showed that dysregulated expression of circular RNAs plays critical roles during the development of several human diseases. Herein, we review the current advance of circular RNAs for their biosynthesis, molecular functions, and implications in human diseases. Impact statement The accumulating evidence indicate that circular RNA (circRNA) is a novel class of noncoding RNA with diverse molecular functions. Our review summarizes the current hypotheses for the models of circRNA biosynthesis including the direct interaction between upstream and downstream introns and lariat-driven circularization. In addition, molecular functions such as a decoy of microRNA (miRNA) termed miRNA sponge, transcriptional regulator, and protein-like modulator are also discussed. Finally, we reviewed the potential roles of circRNAs in neural system, cardiovascular system as well as cancers. These should provide insightful information for studying the regulation and functions of circRNA in other model of human diseases.

A circularly polarized Ka-band stacked patch antenna with increased gain

NASA Technical Reports Server (NTRS)

Zawadzki, M.

2002-01-01

Stacking layers of microstrip patches is a technique often used to improve the bandwidth of a patch antenna, but rarely used to increase its gain. The work presented here scales the three-layer S-band work done in to Ka-band.

Graphic design of pinhole cameras

NASA Technical Reports Server (NTRS)

Edwards, H. B.; Chu, W. P.

1979-01-01

The paper describes a graphic technique for the analysis and optimization of pinhole size and focal length. The technique is based on the use of the transfer function of optical elements described by Scott (1959) to construct the transfer function of a circular pinhole camera. This transfer function is the response of a component or system to a pattern of lines having a sinusoidally varying radiance at varying spatial frequencies. Some specific examples of graphic design are presented.

Fatigue crack detection and identification by the elastic wave propagation method

NASA Astrophysics Data System (ADS)

Stawiarski, Adam; Barski, Marek; Pająk, Piotr

2017-05-01

In this paper the elastic wave propagation phenomenon was used to detect the initiation of the fatigue damage in isotropic plate with a circular hole. The safety and reliability of structures mostly depend on the effectiveness of the monitoring methods. The Structural Health Monitoring (SHM) system based on the active pitch-catch measurement technique was proposed. The piezoelectric (PZT) elements was used as an actuators and sensors in the multipoint measuring system. The comparison of the intact and defected structures has been used by damage detection algorithm. One part of the SHM system has been responsible for detection of the fatigue crack initiation. The second part observed the evolution of the damage growth and assess the size of the defect. The numerical results of the wave propagation phenomenon has been used to present the effectiveness and accuracy of the proposed method. The preliminary experimental analysis has been carried out during the tension test of the aluminum plate with a circular hole to determine the efficiency of the measurement technique.

Radiation Characteristics of Cavity Backed Aperture Antennas in Finite Ground Plane Using the Hybrid FEM/MoM Technique and Geometrical Theory of Diffraction

NASA Technical Reports Server (NTRS)

Reddy, C. J.; Deshpande, M. D.; Cockrell, C. R.; Beck, F. B.

1996-01-01

A technique using hybrid Finite Element Method (FEM)/Method of Moments (MoM), and Geometrical Theory of Diffraction (GTD) is presented to analyze the radiation characteristics of cavity fed aperture antennas in a finite ground plane. The cavity which excites the aperture is assumed to be fed by a cylindrical transmission line. The electromagnetic (EM) fields inside the cavity are obtained using FEM. The EM fields and their normal derivatives required for FEM solution are obtained using (1) the modal expansion in the feed region and (2) the MoM for the radiating aperture region(assuming an infinite ground plane). The finiteness of the ground plane is taken into account using GTD. The input admittance of open ended circular, rectangular, and coaxial line radiating into free space through an infinite ground plane are computed and compared with earlier published results. Radiation characteristics of a coaxial cavity fed circular aperture in a finite rectangular ground plane are verified with experimental results.

Composite materials research and education program: The NASA-Virginia Tech composites program

NASA Technical Reports Server (NTRS)

Herakovich, C. T.

1980-01-01

Major areas of study include: (1) edge effects in finite width laminated composites subjected to mechanical, thermal and hygroscopic loading with temperature dependent material properties and the influence of edge effects on the initiation of failure; (2) shear and compression testing of composite materials at room and elevated temperatures; (3) optical techniques for precise measurement of coefficients of thermal expansion of composites; (4) models for the nonlinear behavior of composites including material nonlinearity and damage accumulation and verification of the models under biaxial loading; (5) compressive failure of graphite/epoxy plates with circular holes and the buckling of composite cylinders under combined compression and torsion; (6) nonlinear mechanical properties of borsic/aluminum, graphite/polyimide and boron/aluminum; (7) the strength characteristics of spliced sandwich panels; and (8) curved graphite/epoxy panels subjected to internal pressure.

Solution of the Inverse Problem for Thin Film Patterning by Electrohydrodynamic Forces

NASA Astrophysics Data System (ADS)

Zhou, Chengzhe; Troian, Sandra

2017-11-01

Micro- and nanopatterning techniques for applications ranging from optoelectronics to biofluidics have multiplied in number over the past decade to include adaptations of mature technologies as well as novel lithographic techniques based on periodic spatial modulation of surface stresses. We focus here on one such technique which relies on shape changes in nanofilms responding to a patterned counter-electrode. The interaction of a patterned electric field with the polarization charges at the liquid interface causes a patterned electrostatic pressure counterbalanced by capillary pressure which leads to 3D protrusions whose shape and evolution can be terminated as needed. All studies to date, however, have investigated the evolution of the liquid film in response to a preset counter-electrode pattern. In this talk, we present solution of the inverse problem for the thin film equation governing the electrohydrodynamic response by treating the system as a transient control problem. Optimality conditions are derived and an efficient corresponding solution algorithm is presented. We demonstrate such implementation of film control to achieve periodic, free surface shapes ranging from simple circular cap arrays to more complex square and sawtooth patterns.

Experimental Modal Analysis of Rectangular and Circular Beams

ERIC Educational Resources Information Center

Emory, Benjamin H.; Zhu, Wei Dong

2006-01-01

Analytical and experimental methods are used to determine the natural frequencies and mode shapes of Aluminum 6061-T651 beams with rectangular and circular cross-sections. A unique test stand is developed to provide the rectangular beam with different boundary conditions including clamped-free, clamped-clamped, clamped-pinned, and pinned-pinned.…

20 CFR 667.500 - What procedures apply to the resolution of findings arising from audits, investigations...

Code of Federal Regulations, 2010 CFR

2010-04-01

..., monitoring and oversight reviews? (a) Resolution of subrecipient-level findings. (1) The Governor is... recipient level OMB Circular A-133 audits. (2) The Secretary uses the DOL audit resolution process... (including OMB Circular A-133 audits) of subrecipients. (2) A State must utilize the audit resolution, debt...

78 FR 13763 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-66; Introduction

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-28

... Regulations Council (Councils) in this Federal Acquisition Circular (FAC) 2005-66. A companion document, the Small Entity Compliance Guide (SECG), follows this FAC. The FAC, including the SECG, is available via... in relation to each FAR case. Please cite FAC 2005-66 and the specific FAR case numbers. For...

77 FR 69713 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-62; Introduction

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-20

... Regulations Council (Councils) in this Federal Acquisition Circular (FAC) 2005-62. A companion document, the Small Entity Compliance Guide (SECG), follows this FAC. The FAC, including the SECG, is available via... in relation to each FAR case. Please cite FAC 2005-62 and the specific FAR case numbers. For...

76 FR 4187 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-49; Introduction

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-24

..., GSA, and NASA in this Federal Acquisition Circular (FAC) 2005-49. A companion document, the Small Entity Compliance Guide (SECG), follows this FAC. The FAC, including the SECG, is available via the... FAR case. Please cite FAC 2005-49 and the specific FAR case number. For information pertaining to...

77 FR 75765 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-64; Introduction

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-21

... (Councils) in this Federal Acquisition Circular (FAC) 2005-64. A companion document, the Small Entity Compliance Guide (SECG), follows this FAC. The FAC, including the SECG, is available via the Internet at http... cite FAC 2005-64 and the specific FAR case number. For information pertaining to status or publication...

77 FR 23363 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-58; Introduction

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-18

...) in this Federal Acquisition Circular (FAC) 2005-58. A companion document, the Small Entity Compliance Guide (SECG), follows this FAC. The FAC, including the SECG, is available via the Internet at http://www... case. Please cite FAC 2005-58 and the specific FAR case numbers. For information pertaining to status...

An all-sky survey of circular polarisation at 200 MHz

NASA Astrophysics Data System (ADS)

Lenc, Emil; Murphy, Tara; Lynch, C. R.; Kaplan, D. L.; Zhang, S. N.

2018-05-01

We present results from the first all-sky radio survey in circular polarisation. The survey uses the Murchison Widefield Array (MWA) to cover 30 900 sq. deg., over declinations south of +30° and north of -86° centred at 200 MHz (over a 169 - 231 MHz band). We achieve a spatial resolution of ˜3' and a typical sensitivity of 3.0 mJy PSF-1 over most of the survey region. We demonstrate a new leakage mitigation technique that reduces the leakage from total intensity into circular polarisation by an order of magnitude. In a blind survey of the imaged region, we detect 14 pulsars in circular polarisation above a 6σ threshold. We also detect six transient sources associated with artificial satellites. A targeted survey of 2 376 pulsars within the surveyed region yielded 33 detections above 4σ. Looking specifically at pulsars previously detected at 200 MHz in total intensity, this represents a 35% detection rate. We also conducted a targeted survey of 2 400 known flare stars, this resulted in two tentative detections above 4σ. A similar targeted search for 1 506 known exoplanets in the field yielded no detections above 4σ. The success of the survey suggests that similar surveys at longer wavelength bands and of deeper fields are warranted.

Fabrication and performance of efficient thin circular polarization gratings with Bragg properties using bulk photo-alignment of a liquid crystalline polymer

NASA Astrophysics Data System (ADS)

Sakhno, Oksana; Gritsai, Yuri; Sahm, Hagen; Stumpe, Joachim

2018-03-01

Thin circular polarization gratings, characterized by high diffraction efficiency and large, up to 42°, diffraction angles were created by polarization holography for the first time. The high efficiency of the gratings is the result of the specific properties of a photo-crosslinkable liquid crystalline polymer and a two-step photochemical/thermal processing procedure. A diffraction efficiency of up to 98% at 532 nm has been achieved for gratings with periods of 700 nm. In contrast to polarization gratings with larger periods these gratings exhibit Bragg properties. So one beam is either transmitted or diffracted depending on the direction of the circular polarization of the incident light, whereas the maximal diffraction efficiency is achieved only at the proper incident angle. The fabrication procedure consists of holographic exposure of the film at room temperature which provides the photo-selective cycloaddition of cinnamic ester groups. Upon subsequent thermal annealing above T g bulk photo-alignment of the LC polymer film occurs enhancing the optical anisotropy within the grating. The holographic patterning provides high spatial resolution, the arbitrary orientation of the LC director as well as high optical quality, thermal and chemical stability of the final gratings. Highly efficient symmetric and slanted circular polarization gratings were fabricated with the proposed technique.

Supercoiled circular DNA of an insect granulosis virus

PubMed Central

Tweeten, Kathleen A.; Bulla, Lee A.; Consigli, Richard A.

1977-01-01

The DNA of the granulosis virus of the Indian meal moth, Plodia interpunctella, was characterized by physical chemical and electron microscopic techniques. Twenty-five percent of the DNA extracted from purified virus was isolated as supercoiled circular molecules. The remaining 75% consisted of relaxed circular molecules. These molecular forms were indicated by the production of two radioactive bands during sedimentation of 3H-labeled granulosis virus DNA in alkaline sucrose gradients or in equilibrium density gradients of neutral cesium chloride/propidium iodide. Electron microscopic visualization of the DNA that banded at the higher density in the latter gradients revealed supercoiled structures whereas that of DNA that banded at the lower density demonstrated relaxed circular molecules. The superhelical molecules were converted to relaxed circles by treatment with pancreatic DNase. The molecular weight of the viral DNA was calculated to be 81 × 106 by sedimentation in neutral sucrose and 78 × 106 by sedimentation in alkaline sucrose. The molecular weight estimated from length measurements in electron micrographs was 76 × 106. The buoyant density of the granulosis virus DNA was 1.703 g/cm3 and that of its insect host DNA was 1.697 g/cm3. Equilibrium sedimentation in cesium chloride and thermal denaturation indicated G + C contents of 44% and 39% for the viral and host DNA, respectively. Images PMID:198791

Numerical and Experimental Investigation of Stratified Gas-Liquid Two-Phase Flow in Horizontal Circular Pipes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Faccini, J.L.H.; Sampaio, P.A.B. de; Su, J.

This paper reports numerical and experimental investigation of stratified gas-liquid two-phase flow in horizontal circular pipes. The Reynolds averaged Navier Stokes equations (RANS) with the k-{omega} model for a fully developed stratified gas-liquid two-phase flow are solved by using the finite element method. A smooth and horizontal interface surface is assumed without considering the interfacial waves. The continuity of the shear stress across the interface is enforced with the continuity of the velocity being automatically satisfied by the variational formulation. For each given interface position and longitudinal pressure gradient, an inner iteration loop runs to solve the nonlinear equations. Themore » Newton-Raphson scheme is used to solve the transcendental equations by an outer iteration to determine the interface position and pressure gradient for a given pair of volumetric flow rates. The interface position in a 51.2 mm ID circular pipe was measured experimentally by the ultrasonic pulse-echo technique. The numerical results were also compared with experimental results in a 21 mm ID circular pipe reported by Masala [1]. The good agreement between the numerical and experimental results indicates that the k-{omega} model can be applied for the numerical simulation of stratified gas-liquid two-phase flow. (authors)« less

Supercoiled circular DNA of an insect granulosis virus.

PubMed

Tweeten, K A; Bulla, L A; Consigli, R A

1977-08-01

The DNA of the granulosis virus of the Indian meal moth, Plodia interpunctella, was characterized by physical chemical and electron microscopic techniques. Twenty-five percent of the DNA extracted from purified virus was isolated as supercoiled circular molecules. The remaining 75% consisted of relaxed circular molecules. These molecular forms were indicated by the production of two radioactive bands during sedimentation of (3)H-labeled granulosis virus DNA in alkaline sucrose gradients or in equilibrium density gradients of neutral cesium chloride/propidium iodide. Electron microscopic visualization of the DNA that banded at the higher density in the latter gradients revealed supercoiled structures whereas that of DNA that banded at the lower density demonstrated relaxed circular molecules. The superhelical molecules were converted to relaxed circles by treatment with pancreatic DNase. The molecular weight of the viral DNA was calculated to be 81 x 10(6) by sedimentation in neutral sucrose and 78 x 10(6) by sedimentation in alkaline sucrose. The molecular weight estimated from length measurements in electron micrographs was 76 x 10(6). The buoyant density of the granulosis virus DNA was 1.703 g/cm(3) and that of its insect host DNA was 1.697 g/cm(3). Equilibrium sedimentation in cesium chloride and thermal denaturation indicated G + C contents of 44% and 39% for the viral and host DNA, respectively.

Modeling radio circular polarization in the Crab nebula

NASA Astrophysics Data System (ADS)

Bucciantini, N.; Olmi, B.

2018-03-01

In this paper, we present, for the first time, simulated maps of the circularly polarized synchrotron emission from the Crab nebula, using multidimensional state of the art models for the magnetic field geometry. Synchrotron emission is the signature of non-thermal emitting particles, typical of many high-energy astrophysical sources, both Galactic and extragalactic ones. Its spectral and polarization properties allow us to infer key information on the particles distribution function and magnetic field geometry. In recent years, our understanding of pulsar wind nebulae has improved substantially thanks to a combination of observations and numerical models. A robust detection or non-detection of circular polarization will enable us to discriminate between an electron-proton plasma and a pair plasma, clarifying once for all the origin of the radio emitting particles, setting strong constraints on the pair production in pulsar magnetosphere, and the role of turbulence in the nebula. Previous attempts at measuring the circular polarization have only provided upper limits, but the lack of accurate estimates, based on reliable models, makes their interpretation ambiguous. We show here that those results are above the expected values, and that current polarimetric techniques are not robust enough for conclusive result, suggesting that improvements in construction and calibration of next generation radio facilities are necessary to achieve the desired sensitivity.

Analysis of a Circular Composite Disk Subjected to Edge Rotations and Hydrostatic Pressure

NASA Technical Reports Server (NTRS)

Oliver, Stanley T.

2004-01-01

The structural analysis results for a graphite/epoxy quasi-isotropic circular plate subjected to a forced rotation at the boundary and pressure is presented. The analysis is to support a specialized material characterization test for composite cryogenic tanks. Finite element models were used to ensure panel integrity and determine the pressure necessary to achieve a predetermined equal biaxial strain value. The displacement results due to the forced rotation at the boundary led to a detailed study of the bending stiffness matrix [D]. The variation of the bending stiffness terms as a function of angular position is presented graphically, as well as, an illustrative technique of considering the laminate as an I-beam.

Advances in circular stapling technique for gastric bypass: transoral placement of the anvil.

PubMed

Nguyen, Ninh T; Hinojosa, Marcelo W; Smith, Brian R; Reavis, Kevin M; Wilson, Samuel E

2008-05-01

In Roux-en-Y gastric bypass, construction of the gastrojejunostomy is commonly performed using a circular stapler. The initial description for placement of the anvil was via the transoral approach. Although the concept was ingenious, technical difficulty was encountered during passage resulting in complications such as hypopharyngeal perforation and esophageal mucosal injury. As a result, most surgeons subsequently changed their route of anvil placement to the transabdominal approach. Advances in stapler technology now allow the head of the anvil to be pre-tilted, permitting transoral introduction with greater ease and safety. This paper describes this improved method for transoral placement of the anvil during laparoscopic gastric bypass and reoperative bariatric surgery.

A conceptual design of shock-eliminating clover combustor for large scale scramjet engine

NASA Astrophysics Data System (ADS)

Sun, Ming-bo; Zhao, Yu-xin; Zhao, Guo-yan; Liu, Yuan

2017-01-01

A new concept of shock-eliminating clover combustor is proposed for large scale scramjet engine to fulfill the requirements of fuel penetration, total pressure recovery and cooling. To generate the circular-to-clover transition shape of the combustor, the streamline tracing technique is used based on an axisymmetric expansion parent flowfield calculated using the method of characteristics. The combustor is examined using inviscid and viscous numerical simulations and a pure circular shape is calculated for comparison. The results showed that the combustor avoids the shock wave generation and produces low total pressure losses in a wide range of flight condition with various Mach number. The flameholding device for this combustor is briefly discussed.

Multi-agent simulation of the von Thunen model formation mechanism

NASA Astrophysics Data System (ADS)

Tao, Haiyan; Li, Xia; Chen, Xiaoxiang; Deng, Chengbin

2008-10-01

This research tries to explain the internal driving forces of circular structure formation in urban geography via the simulation of interaction between individual behavior and market. On the premise of single city center, unchanged scale merit and complete competition, enterprise migration theory as well, an R-D algorithm, that has agents searched the best behavior rules in some given locations, is introduced with agent-based modeling technique. The experiment conducts a simulation on Swarm platform, whose result reflects and replays the formation process of Von Thünen circular structure. Introducing and considering some heterogeneous factors, such as traffic roads, the research verifies several landuse models and discusses the self-adjustment function of price mechanism.

Circularized Chromosome with a Large Palindromic Structure in Streptomyces griseus Mutants

PubMed Central

Uchida, Tetsuya; Ishihara, Naoto; Zenitani, Hiroyuki; Hiratsu, Keiichiro; Kinashi, Haruyasu

2004-01-01

Streptomyces linear chromosomes display various types of rearrangements after telomere deletion, including circularization, arm replacement, and amplification. We analyzed the new chromosomal deletion mutants Streptomyces griseus 301-22-L and 301-22-M. In these mutants, chromosomal arm replacement resulted in long terminal inverted repeats (TIRs) at both ends; different sizes were deleted again and recombined inside the TIRs, resulting in a circular chromosome with an extremely large palindrome. Short palindromic sequences were found in parent strain 2247, and these sequences might have played a role in the formation of this unique structure. Dynamic structural changes of Streptomyces linear chromosomes shown by this and previous studies revealed extraordinary strategies of members of this genus to keep a functional chromosome, even if it is linear or circular. PMID:15150216

Cup waveguide antenna with integrated polarizer and OMT

NASA Technical Reports Server (NTRS)

Kory, Carol (Inventor); Acosta, Roberto J. (Inventor); Lambert, Kevin M. (Inventor)

2011-01-01

A cup waveguide antenna with integrated polarizer and OMT for simultaneously communicating left and right hand circularly polarized electromagnetic waves is adjustable to obtain efficient propagation and reception of electromagnetic waves. The antenna includes a circular waveguide having an orthomode transducer utilizing first and second pins longitudinally spaced apart and oriented orthogonally with respect to each other. Six radially-oriented adjustable polarizer screws extend from the exterior to the interior of the waveguide. A septum intermediate the first and second pins is aligned with the first pin. Adjustment of the polarizer screws enables maximized propagation of and/or response to left hand circularly polarized electromagnetic waves by the first pin while simultaneously enabling maximized propagation of and/or response to right hand circularly polarized electromagnetic waves by the second pin.

Two-Phase Flow in Microchannels with Non-Circular Cross Section

NASA Astrophysics Data System (ADS)

Eckett, Chris A.; Strumpf, Hal J.

2002-11-01

Two-phase flow in microchannels is of practical importance in several microgravity space technology applications. These include evaporative and condensing heat exchangers for thermal management systems and vapor cycle systems, phase separators, and bioreactors. The flow passages in these devices typically have a rectangular cross-section or some other non-circular cross-section; may include complex flow paths with branches, merges and bends; and may involve channel walls of different wettability. However, previous experimental and analytical investigations of two-phase flow in reduced gravity have focussed on straight, circular tubes. This study is an effort to determine two-phase flow behavior, both with and without heat transfer, in microchannel configurations other than straight, circular tubes. The goals are to investigate the geometrical effects on flow pattern, pressure drop and liquid holdup, as well as to determine the relative importance of capillary, surface tension, inertial, and gravitational forces in such geometries. An evaporative heat exchanger for microgravity thermal management systems has been selected as the target technology in this investigation. Although such a heat exchanger has never been developed at Honeywell, a preliminary sizing has been performed based on knowledge of such devices in normal gravity environments. Fin shapes considered include plain rectangular, offset rectangular, and wavy fin configurations. Each of these fin passages represents a microchannel of non-circular cross section. The pans at the inlet and outlet of the heat exchanger are flow branches and merges, with up to 90-deg bends. R-134a has been used as the refrigerant fluid, although ammonia may well be used in the eventual application.

Low-Power Testing of Losses in Millimeter-Wave Transmission Lines for High-Power Applications

PubMed Central

Han, S. T.; Comfoltey, E. N.; Shapiro, M. A.; Sirigiri, J. R.; Tax, D. S.; Temkin, R. J.; Woskov, P. P.; Rasmussen, D. A.

2008-01-01

We report the measurement of small losses in transmission line (TL) components intended for high-power millimeter-wave applications. Measurements were made using two different low-power techniques: a coherent technique using a vector network analyzer (VNA) and an incoherent technique using a radiometer. The measured loss in a 140 GHz 12.7 mm diameter TL system, consisting of 1.7 m of circular corrugated waveguide and three miter bends, is dominated by the miter bend loss. The measured loss was 0.3±0.1 dB per miter bend using a VNA; and 0.22±0.1 dB per miter bend using a radiometer. Good agreement between the two measurement techniques implies that both are useful for measuring small losses. To verify the methodology, the VNA technique was employed to measure the extremely small transmission loss in a 170 GHz ITER prototype TL system consisting of three lengths of 1 m, 63.5 mm diameter, circular corrugated waveguide and two miter bends. The measured loss of 0.05±0.02 dB per miter bend may be compared with the theoretical loss of 0.027 dB per miter bend. These results suggest that low-power testing of TL losses, utilizing a small, simple TL system and a VNA, is a reliable method for evaluating performance of low-loss millimeter-wave TL components intended for use in high-power applications. PMID:19081774

A solution to the Navier-Stokes equations based upon the Newton Kantorovich method

NASA Technical Reports Server (NTRS)

Davis, J. E.; Gabrielsen, R. E.; Mehta, U. B.

1977-01-01

An implicit finite difference scheme based on the Newton-Kantorovich technique was developed for the numerical solution of the nonsteady, incompressible, two-dimensional Navier-Stokes equations in conservation-law form. The algorithm was second-order-time accurate, noniterative with regard to the nonlinear terms in the vorticity transport equation except at the earliest few time steps, and spatially factored. Numerical results were obtained with the technique for a circular cylinder at Reynolds number 15. Results indicate that the technique is in excellent agreement with other numerical techniques for all geometries and Reynolds numbers investigated, and indicates a potential for significant reduction in computation time over current iterative techniques.

[Technical questions of the transrectal specimen extraction].

PubMed

Lukovich, Péter; Csibi, Noémi; Bokor, Attila

2016-03-01

During laparoscopic partial colectomy the specimen can be extracted transrectally. This technique decreases the invasiveness of the surgery, because the abdominal wall incision is avoided. Premises of a new surgical technique are precise technical description as well as a favourable balance of advantages and disadvantages. In this paper the authors review the technique they apply and analyse their first results. 45 laparoscopic bowel resections were performed by a multidisciplinary team between 16th April 2014 and 1st November 2015. Indication of surgery was endometriosis, and the specimen was extracted transrectally in 11 patients. Having ligated both bowel ends proximal and distal to the section infiltrated with endometriosis, and the proximal bowel secured with a laparoscopic bulldog. Then the bowel was resected and the specimen was extracted in a camera bag transrectally. A purse-string suture was placed into the proximal bowel end, and the anvil of the circular stapler--which was introduced transrectally--was inserted into the bowel. After closing the rectal stump, the anastomosis was performed with a circular stapler. We used this technique when the upper third of the rectum or sigmoid colon was infiltrated with endometriosis. The difference between the operation time of the two techniques (transabdominal vs. transrectal specimen extraction: 108 min vs. 118 min) was not significant. There was not difference in the WBC count between the first and second postoperative day, and there was not any anastomosis leakage detected either. By using the above technique, postoperative infections could have been reduced to minimum. Transrectal specimen extraction did not increase postoperative complication The authors believe this is a safe way of specimen extraction after partial colectomy.

Helicity-selective phase-matching and quasi-phase matching of circularly polarized high-order harmonics: towards chiral attosecond pulses

DOE PAGES

Kfir, Ofer; Grychtol, Patrik; Turgut, Emrah; ...

2016-05-23

Phase matching of circularly polarized high-order harmonics driven by counter-rotating bi-chromatic lasers was recently predicted theoretically and demonstrated experimentally. In that work, phase matching was analyzed by assuming that the total energy, spin angular momentum and linear momentum of the photons participating in the process are conserved. Here we propose a new perspective on phase matching of circularly polarized high harmonics. We derive an extended phase matching condition by requiring a new propagation matching condition between the classical vectorial bi-chromatic laser pump and harmonics fields. This allows us to include the influence of the laser pulse envelopes on phase matching.more » Here, we find that the helicity dependent phase matching facilitates generation of high harmonics beams with a high degree of chirality. Indeed, we present an experimentally measured chiral spectrum that can support a train of attosecond pulses with a high degree of circular polarization. Moreover, while the degree of circularity of the most intense pulse approaches unity, all other pulses exhibit reduced circularity. Lastly, this feature suggests the possibility of using a train of attosecond pulses as an isolated attosecond probe for chiral-sensitive experiments.« less

An Empirical Evaluation of Five Circular Error Probable Estimation Techniques and a Method for Improving Them

DTIC Science & Technology

1993-03-10

template which runs a Romberg algorithm in the background to numerically integrate the BVN [12:257]. Appendix A als- lists the results from two other...for computing these values: a Taylor series expansion, the Romberg algorithm , and the CBN technique. Appendix A lists CEPpop. values for eleven...determining factor in this selection process. Of the 175 populations ex- amined in the experiment, the MathCAD version of the Romberg algorithm failed

Optical detection of paramagnetic centres: From crystals to glass-ceramics

NASA Astrophysics Data System (ADS)

Rogulis, Uldis

2016-07-01

An unambiguous attribution of the absorption spectra to definite paramagnetic centres identified by the EPR techniques in the most cases is problematic. This problem may be solved by applying of a direct measurement techniques—the EPR detected via the magnetic circular dichroism, or briefly MCD-EPR. The present survey reports on the advantages and disadvantages applying the MCD-EPR techniques to simple and complex paramagnetic centres in crystals as well as glasses and glass-ceramics.

Higher order parametric excitation modes for spaceborne quadrupole mass spectrometers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gershman, D. J.; Block, B. P.; Rubin, M.

This paper describes a technique to significantly improve upon the mass peak shape and mass resolution of spaceborne quadrupole mass spectrometers (QMSs) through higher order auxiliary excitation of the quadrupole field. Using a novel multiresonant tank circuit, additional frequency components can be used to drive modulating voltages on the quadrupole rods in a practical manner, suitable for both improved commercial applications and spaceflight instruments. Auxiliary excitation at frequencies near twice that of the fundamental quadrupole RF frequency provides the advantages of previously studied parametric excitation techniques, but with the added benefit of increased sensed excitation amplitude dynamic range and themore » ability to operate voltage scan lines through the center of upper stability islands. Using a field programmable gate array, the amplitudes and frequencies of all QMS signals are digitally generated and managed, providing a robust and stable voltage control system. These techniques are experimentally verified through an interface with a commercial Pfeiffer QMG422 quadrupole rod system. When operating through the center of a stability island formed from higher order auxiliary excitation, approximately 50% and 400% improvements in 1% mass resolution and peak stability were measured, respectively, when compared with traditional QMS operation. Although tested with a circular rod system, the presented techniques have the potential to improve the performance of both circular and hyperbolic rod geometry QMS sensors.« less

Assessment of Undiscovered Deposits of Gold, Silver, Copper, Lead, and Zinc in the United States: A Portable Document (PDF) Recompilation of USGS Open-File Report 96-96 and Circular 1178

USGS Publications Warehouse

U.S. Geological Survey National Mineral Resource Assessment Team Recompiled by Schruben, Paul G.

2002-01-01

This publication contains the results of a national mineral resource assessment study. The study (1) identifies regional tracts of ground believed to contain most of the nation's undiscovered resources of gold, silver, copper, lead, and zinc in conventional types of deposits; and (2) includes probabilistic estimates of the amounts of these undiscovered resources in most of the tracts. It also contains a table of the significant known deposits in the tracts, and includes descriptions of the mineral deposit models used for the assessment. The assessment was previously released in two major publications. The conterminous United States assessment was published in 1996 as USGS Open-File Report 96-96. Subsequently, the Alaska assessment was combined with the conterminous assessment in 1998 and released as USGS Circular 1178. This new recompilation was undertaken for several reasons. First, the graphical browser software used in Circular 1178 was ONLY compatible with the Microsoft Windows operating system. It was incompatible with the Macintosh operating system, Linux, and other types of Unix computers. Second, the browser on Circular 1178 is much less intuitive to operate, requiring most users to follow a tutorial to understand how to navigate the information on the CD. Third, this release corrects several errors and numbering inconsistencies in Circular 1178.

Protein Self-Assembly and Protein-Induced DNA Morphologies

NASA Astrophysics Data System (ADS)

Mawhinney, Matthew T.

The ability of biomolecules to associate into various structural configurations has a substantial impact on human physiology. The synthesis of protein polypeptide chains using the information encoded by DNA is mediated through the use of regulatory proteins, known as transcription factors. Some transcription factors perform function by inducing local curvature in deoxyribonucleic acid (DNA) strands, the mechanisms of which are not entirely known. An important architectural protein, eleven zinc finger CTCF (11 ZF CTCF) is involved in genome organization and hypothesized to mediate DNA loop formation. Direct evidence for these CTCF-induced DNA loops has yet to be observed. In this thesis, the effect of 11 ZF CTCF on DNA morphology is examined using atomic force microscopy, a powerful technique for visualizing biomolecules with nanometer resolution. The presence of CTCF is revealed to induce a variety of morphologies deviating from the relaxed state of control DNA samples, including compact circular complexes, meshes, and networks. Images reveal quasi-circular DNA/CTCF complexes consistent with a single DNA molecule twice wrapped around the protein. The structures of DNA and proteins are highly important for operations in the cell. Structural irregularities may lead to a variety of issues, including more than twenty human pathologies resulting from aberrant protein misfolding into amyloid aggregates of elongated fibrils. Insulin deficiency and resistance characterizing type 2 diabetes often requires administration of insulin. Injectable and inhalable delivery methods have been documented to result in the deposition of amyloid fibrils. Oligomers, soluble multiprotein assemblies, are believed to play an important role in this process. Insulin aggregation under physiological conditions is not well understood and oligomers have not yet been fully characterized. In this thesis, in vitro insulin aggregation at acidic and neutral pH is explored using a variety of techniques, including kinetic thioflavin T fluorescence, circular dichroism spectroscopy, atomic force and electron microscopy imaging. The size distribution of insulin oligomers at different assembly stages is characterized through covalent cross-linking and gel electrophoresis. Results show that at the earliest assembly stage, oligomers comprise up to 40% and 70% of soluble insulin at acidic and neutral pH, respectively. While the highest oligomer order increases with insulin concentration at acidic pH, the opposite tendency is observed at neutral pH, with heptamers formed in 10 muM insulin. These findings suggest that oligomers may be on- and off- pathway assemblies for insulin at acidic and neutral pH, respectively. Agitation, required to induce insulin aggregation at neutral pH, increases fibril formation rate and fibrillar mass by an order of magnitude each. Insulin incubated under agitated conditions at neutral pH rapidly aggregates into large micrometer-sized aggregates, which provides insight into injection-site amyloidosis and toxic pulmonary aggregates induced by administration of extraneous insulin.

Quantitative flow visualization applied to wake flow studies

NASA Astrophysics Data System (ADS)

Rukweza, Godfrey

An experimental study of the flow past stationary cylinders of circular, triangular and rectangular cross-section in cross-flow has been made using three different techniques. These are hot-film anemometry, smoke-wire flow visualization, and particle image velocimetry. The point measurement technique of constant temperature hot-film anemometry was used to confirm the findings of earlier investigations on the performance of cylinders with rectangular and triangular cross-sections. The thesis presents distributions of the mean streamwise velocity, fluctuation levels and spectra in the Reynolds number range 200 < Re[D] < 2.2 x 10[4]. Variations of the vortex shedding frequency with Reynolds number within the near-wake region are shown and related to the flow patterns obtained using the technique of smoke-wire flow visualisation. Finally, PIV was applied in a water channel to determine wake flow properties created by a circular cylinder at three Reynolds numbers of 200, 300 and 2.2 x 10[4]. For the PIV investigation, a technique was developed which enables a continuous wave laser beam to be pulsed using a Bragg cell : this system can be used to produce pulses of light which are separated by a specified time interval which is typically in the range 10[-4] to 10[-2] s. This was successfully used in the implementation of PIV in the highest Reynolds number conditions for which standard video frame rates of 25 fps are inadequate. In this relatively high speed flow, a novel technique was also developed for sampling the image data of seeding particles at a fixed phase. This enabled the phase-averaging of data derived by analysis of PIV system output with a good degree of success. Analysis of the flow image data was then performed using a customized PIV software package developed in the Department, in conjunction with a special purpose software package QFV. Results are presented for both the instantaneous and the phase-averaged distributions of velocity, vorticity, and shear in the near-wake of a stationary, circular-section cylinder in cross-flow, the phase-averaging being applied only to the two low Reynolds number flows because hardware limitations precluded phase sampling at the highest Reynolds number. These results reveal the time evolution of the flow in the near-wake region and also permit estimates to be made of the vortex convection velocities in the near-wake flow field. The experimental results are in close agreement with those previously published in the literature, including those obtained using a variety of different techniques. Qualitative consideration is given to the general experimental errors which are encountered in PIV and the limitations on accuracy of PIV implementation in wake flow are reviewed. The overall outcome of the investigation is seen to be a better and systematic understanding of the flow in the near-wake of a cylinder in cross-flow. This improved understanding is coupled with a wealth of detailed data which shows how the large scale motion is superimposed on the wake flow region.

Microwave Ablation: Comparison of Simultaneous and Sequential Activation of Multiple Antennas in Liver Model Systems.

PubMed

Harari, Colin M; Magagna, Michelle; Bedoya, Mariajose; Lee, Fred T; Lubner, Meghan G; Hinshaw, J Louis; Ziemlewicz, Timothy; Brace, Christopher L

2016-01-01

To compare microwave ablation zones created by using sequential or simultaneous power delivery in ex vivo and in vivo liver tissue. All procedures were approved by the institutional animal care and use committee. Microwave ablations were performed in both ex vivo and in vivo liver models with a 2.45-GHz system capable of powering up to three antennas simultaneously. Two- and three-antenna arrays were evaluated in each model. Sequential and simultaneous ablations were created by delivering power (50 W ex vivo, 65 W in vivo) for 5 minutes per antenna (10 and 15 minutes total ablation time for sequential ablations, 5 minutes for simultaneous ablations). Thirty-two ablations were performed in ex vivo bovine livers (eight per group) and 28 in the livers of eight swine in vivo (seven per group). Ablation zone size and circularity metrics were determined from ablations excised postmortem. Mixed effects modeling was used to evaluate the influence of power delivery, number of antennas, and tissue type. On average, ablations created by using the simultaneous power delivery technique were larger than those with the sequential technique (P < .05). Simultaneous ablations were also more circular than sequential ablations (P = .0001). Larger and more circular ablations were achieved with three antennas compared with two antennas (P < .05). Ablations were generally smaller in vivo compared with ex vivo. The use of multiple antennas and simultaneous power delivery creates larger, more confluent ablations with greater temperatures than those created with sequential power delivery. © RSNA, 2015.

Analysis of blood flow with nanoparticles induced by uniform magnetic field through a circular cylinder with fractional Caputo derivatives

NASA Astrophysics Data System (ADS)

Abdullah, M.; Butt, Asma Rashid; Raza, Nauman; Alshomrani, Ali Saleh; Alzahrani, A. K.

2018-01-01

The magneto hydrodynamic blood flow in the presence of magnetic particles through a circular cylinder is investigated. To calculate the impact of externally applied uniform magnetic field, the blood is electrically charged. Initially the fluid and circular cylinder is at rest but at time t =0+ , the cylinder starts to oscillate along its axis with velocity fsin (Ωt) . To obtain the mathematical model of blood flow with fractional derivatives Caputo fractional operator is employed. The solutions for the velocities of blood and magnetic particles are procured semi analytically by using Laplace transformation method. The inverse Laplace transform has been calculated numerically by using MATHCAD computer software. The obtained results of velocities are presented in Laplace domain in terms of modified Bessel function I0 (·) . The obtained results satisfied all imposed initial and boundary conditions. The hybrid technique that is employed here less computational effort and time cost as compared to other techniques used in literature. As the limiting cases of our results the solutions of the flow model with ordinary derivatives has been procured. Finally, the impact of Reynolds number Re, fractional parameter α and Hartmann number Ha is analyzed and portrayed through graphs. It is worthy to pointing out that fractional derivatives brings remarkable differences as compared to ordinary derivatives. It also has been observed that velocity of blood and magnetic particles is weaker under the effect of transverse magnetic field.

Polarimetric Imaging System for Automatic Target Detection and Recognition

DTIC Science & Technology

2000-03-01

technique shown in Figure 4(b) can also be used to integrate polarizer arrays with other types of imaging sensors, such as LWIR cameras and uncooled...vertical stripe pattern in this φ image is caused by nonuniformities in the particular polarizer array used. 2. CIRCULAR POLARIZATION IMAGING USING

Edge-following algorithm for tracking geological features

NASA Technical Reports Server (NTRS)

Tietz, J. C.

1977-01-01

Sequential edge-tracking algorithm employs circular scanning to point permit effective real-time tracking of coastlines and rivers from earth resources satellites. Technique eliminates expensive high-resolution cameras. System might also be adaptable for application in monitoring automated assembly lines, inspecting conveyor belts, or analyzing thermographs, or x ray images.

A Rotating Source Polarization Measurement Technique Using Two Circularly Polarized Antennas

DTIC Science & Technology

2016-07-15

antenna with high polarization purity. The axial ratio of the polarization ellipse was determined from the ripple in the voltage received by the...is shown in Fig. 6. The linear phase progression has been removed from the phase measurements to show a ripple . The corresponding polarization ratio

Inductive coupler for downhole components and method for making same

DOEpatents

Hall, David R.; Hall, Jr., H. Tracy; Pixton, David S.; Dahlgren, Scott; Sneddon, Cameron; Fox, Joe; Briscoe, Michael A.

2006-10-03

An inductive coupler for downhole components. The inductive coupler includes an annular housing having a recess defined by a bottom portion and two opposing side wall portions. At least one side wall portion includes a lip extending toward but not reaching the other side wall portion. A plurality of generally U-shaped MCEI segments, preferably comprised of ferrite, are disposed in the recess and aligned so as to form a circular trough. The coupler further includes a conductor disposed within the circular trough and a polymer filling spaces between the segments, the annular housing and the conductor.

Circular electrodes to reduce the current variation of OTFTs with the drop-casted semiconducting layer

NASA Astrophysics Data System (ADS)

Dipu Kabir, H. M.; Ahmed, Zubair; Kariyadan, Remashan; Zhang, Lining; Chan, Mansun

2018-06-01

Circular organic thin film transistor (OTFT) structures are proposed to reduce the impact of variable grain alignment on the drive current of the polycrystalline organic thin film transistor (OTFT). As the circular structure is planar symmetric, the orientation of the grain cannot affect the drive current of the circular OTFT. Thus, circular electrodes expected to provide a lower variation. Top-gate, bottom-contact circular and conventional OTFTs with drop-casted polycrystalline 6,13-Bis(triisopropyl-silylethynyl) (TIPS)-Pentacene organic semiconducting layer (OSC) are fabricated to verify the theoretical variation reduction. The relative standard deviation (RSD), defined as the ratio of standard deviation and the average of drive current is used as the degree of variations in different structures. According to our fabrication result, circular transistors have a significantly lower variation (20% RSD), compared to the variation of conventional OTFTs (61% RSD). His research interests include Organic Electronics, VLSI Design, Embedded System, Neural Networks, and Solid-state devices. Between July 2001 and December 2002, he was a Visiting Professor at University of California at Berkeley and the Co-director of the BSIM program. He is currently still consulting on the development of the next generation compact models. He has been actively contributing to the professional community and hold many positions. He was a Board of Governor, Chair of the Education Committee, the Chair of the Region 10 subcommittee and a Distinguished lecturer of the IEEE Electron Device Society. He has also chaired many international conferences and acting as editors for a number of technical journals. In addition, he has received many awards including the UC Regents Fellowship, Golden Keys Scholarship for Academic Excellence, SRC Inventor Recognition Award, Rockwell Research Fellowship, R&D 100 award (for the BSIM3v3 project), Distinguished Teaching Award, the Shenzhen Science and Technology Innovation awards, and EDS Education Award etc. He is a Fellow of HKIE, IET and IEEE.

Heat Transfer Enhancement for Finned-Tube Heat Exchangers with Vortex Generators: Experimental and Numerical Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Brien, James Edward; Sohal, Manohar Singh; Huff, George Albert

2002-08-01

A combined experimental and numerical investigation is under way to investigate heat transfer enhancement techniques that may be applicable to large-scale air-cooled condensers such as those used in geothermal power applications. The research is focused on whether air-side heat transfer can be improved through the use of finsurface vortex generators (winglets,) while maintaining low heat exchanger pressure drop. A transient heat transfer visualization and measurement technique has been employed in order to obtain detailed distributions of local heat transfer coefficients on model fin surfaces. Pressure drop measurements have also been acquired in a separate multiple-tube row apparatus. In addition, numericalmore » modeling techniques have been developed to allow prediction of local and average heat transfer for these low-Reynolds-number flows with and without winglets. Representative experimental and numerical results presented in this paper reveal quantitative details of local fin-surface heat transfer in the vicinity of a circular tube with a single delta winglet pair downstream of the cylinder. The winglets were triangular (delta) with a 1:2 height/length aspect ratio and a height equal to 90% of the channel height. Overall mean fin-surface Nusselt-number results indicate a significant level of heat transfer enhancement (average enhancement ratio 35%) associated with the deployment of the winglets with oval tubes. Pressure drop measurements have also been obtained for a variety of tube and winglet configurations using a single-channel flow apparatus that includes four tube rows in a staggered array. Comparisons of heat transfer and pressure drop results for the elliptical tube versus a circular tube with and without winglets are provided. Heat transfer and pressure-drop results have been obtained for flow Reynolds numbers based on channel height and mean flow velocity ranging from 700 to 6500.« less

Projectile and Circular Motion: A Model Four-Week Unit of Study for a High School Physics Class Using Physics Courseware.

ERIC Educational Resources Information Center

Geigel, Joan; And Others

A self-paced program designed to integrate the use of computers and physics courseware into the regular classroom environment is offered for physics high school teachers in this module on projectile and circular motion. A diversity of instructional strategies including lectures, demonstrations, videotapes, computer simulations, laboratories, and…

NOTE: Circular symmetry in topologically massive gravity

NASA Astrophysics Data System (ADS)

Deser, S.; Franklin, J.

2010-05-01

We re-derive, compactly, a topologically massive gravity (TMG) decoupling theorem: source-free TMG separates into its Einstein and Cotton sectors for spaces with a hypersurface-orthogonal Killing vector, here concretely for circular symmetry. We then generalize the theorem to include matter; surprisingly, the single Killing symmetry also forces conformal invariance, requiring the sources to be null.

A note on the modelling of circular smallholder migration.

PubMed

Bigsten, A

1988-01-01

"It is argued that circular migration [in Africa] should be seen as an optimization problem, where the household allocates its labour resources across activities, including work which requires migration, so as to maximize the joint family utility function. The migration problem is illustrated in a simple diagram, which makes it possible to analyse economic aspects of migration." excerpt

Circularly polarized measurements of radar backscatter from terrain

NASA Astrophysics Data System (ADS)

Wilson, E. A.; Brunfeldt, D. R.; Ulaby, F. T.; Holtzman, J. C.

1980-02-01

This report documents the design changes to the University of Kansas MAS 8-18/35 scatterometer system required to incorporate a circular polarization capability and a subsequent backscatter measurement program. The modifications enable the MAS 8-18/35 system to acquire both linear (HH, HV, VV) and circular (RR, RL, LL) radar backscatter data over its entire operating range of 8-18 GHz and 35 GHz. The measurement program described herein consisted of measurements of the backscatter coefficient, as a function of the angle of incidence (0-80) at selected frequencies in the 8-18 GHz range using circular polarization. Targets studied included coniferous and deciduous trees, wet and dry asphalt and concrete and bare and plowed ground at various moisture conditions. Coniferous and deciduous tree measurements were taken in both August and November so that seasonal changes could be observed.

Circular Bacteriocins: Biosynthesis and Mode of Action

PubMed Central

Brede, Dag A.; Nes, Ingolf F.; Diep, Dzung B.

2014-01-01

Circular bacteriocins are a group of N-to-C-terminally linked antimicrobial peptides, produced by Gram-positive bacteria of the phylum Firmicutes. Circular bacteriocins generally exhibit broad-spectrum antimicrobial activity, including against common food-borne pathogens, such as Clostridium and Listeria spp. These peptides are further known for their high pH and thermal stability, as well as for resistance to many proteolytic enzymes, properties which make this group of bacteriocins highly promising for potential industrial applications and their biosynthesis of particular interest as a possible model system for the synthesis of highly stable bioactive peptides. In this review, we summarize the current knowledge on this group of bacteriocins, with emphasis on the recent progress in understanding circular bacteriocin genetics, biosynthesis, and mode of action; in addition, we highlight the current challenges and future perspectives for the application of these peptides. PMID:25172850

The development of laser speckle velocimetry for the study of vortical flows

NASA Technical Reports Server (NTRS)

Krothapalli, A.

1991-01-01

A new experimental technique commonly known as PIDV (particle image displacement velocity) was developed to measure an instantaneous two dimensional velocity fluid in a selected plane of the flow field. This technique was successfully applied to the study of several problems: (1) unsteady flows with large scale vortical structures; (2) the instantaneous two dimensional flow in the transition region of a rectangular air jet; and (3) the instantaneous flow over a circular bump in a transonic flow. In several other experiments PIDV is routinely used as a non-intrusive measurement technique to obtain instantaneous two dimensional velocity fields.

Study of LED layout in indoor visible light communication and performance analysis

NASA Astrophysics Data System (ADS)

Wang, Jiaan; Che, Ying; Wang, Xinlan; Guo, Linyang; Li, Jing

2017-10-01

Light emitting diodes(LED) could provide both illumination and data communication in indoor visible light communication(VLC) that owns the modulation bandwith from several from several MHz to seneral hundreds of MHz. The layout of LED plays an important role in maintaining a steady optical power distribution over the receiving plane. The existing rectangular LED layout does not provide a full coverage on the receiving plane leaving receiving optical power outage area, which in turn affects the best performance of the VLC system. This paper design a circular layout scheme of LED in 5mX5mX3m room based on the criterion of the illumination minimum mean square deviation. The influence of the distribution of the intensity of illumination with the radius of 1m and 1.5m,for including the wall reflection and not including the wall reflection, and make a comparison with rectangular LED layout of illumination distribution, when the number of LEDs with rectangular layout as same as circular layout. Including the number of LEDs are 4 and 16.For a specific simulation parameters as following:height of receiving plane is 0.85m,a single LEDs is composed of 60X60 LED chips, the parameters of a single chip is that transmitting power is 20mW,center luminous intensity is 0.73cd.semiangle at half power is 70deg.The parameters of concentrator is that photodiode area is 1cm2,photodiode responsivity is 0.4,field of view at the receiver is 85deg.Other parameters are that reflective index of concentrator is 1.5,reflectivity of wall is 0.8.Circular layout and rectangular layout are analyzed through simulation of the received optical power distribution, signal noise ratio distribution in non line of sight(including the wall reflection) and line of sight(not including the wall reflection),when the number of the LED is different. It is clear from the results that the received optical power distribution of non line of sight is better than line of sight, when the number of the LED are same, but the signal noise ratio distribution is decreased result of the reflection of the wall. It is found that the received optical power of circular layout is better than the received optical power distribution of rectangulr layout, and circular layout is a good solution that add the received optical power at the 4 corners of room, improve the system ability of communication, when making a contrast of rectangular lyout with circular layout,at the same time,the fluctuate of circular layout's signal to noise ratio of is smller than rectangular layuot.The radius of circular layout or the location of rectangular layout is keeping, the received optical power of receiving plane is increased, by adding the number of LED,in the meantime, the interference between LED light source also increase. But the increase of the circular layout radius when the number of LED remain the same is helpful to reduce the inter symbol interference that work out between LED each other, enhance the system signal noise ratio. In this paper, the results of the reaearch provides a new idea for indoor visible light communication with non-standard room (Size of room is not 5mX5mX3m), at the same time, provides guiding significance for future setting up the indoor visible light communication links.

Two-craft Coulomb formation study about circular orbits and libration points

NASA Astrophysics Data System (ADS)

Inampudi, Ravi Kishore

This dissertation investigates the dynamics and control of a two-craft Coulomb formation in circular orbits and at libration points; it addresses relative equilibria, stability and optimal reconfigurations of such formations. The relative equilibria of a two-craft tether formation connected by line-of-sight elastic forces moving in circular orbits and at libration points are investigated. In circular Earth orbits and Earth-Moon libration points, the radial, along-track, and orbit normal great circle equilibria conditions are found. An example of modeling the tether force using Coulomb force is discussed. Furthermore, the non-great-circle equilibria conditions for a two-spacecraft tether structure in circular Earth orbit and at collinear libration points are developed. Then the linearized dynamics and stability analysis of a 2-craft Coulomb formation at Earth-Moon libration points are studied. For orbit-radial equilibrium, Coulomb forces control the relative distance between the two satellites. The gravity gradient torques on the formation due to the two planets help stabilize the formation. Similar analysis is performed for along-track and orbit-normal relative equilibrium configurations. Where necessary, the craft use a hybrid thrusting-electrostatic actuation system. The two-craft dynamics at the libration points provide a general framework with circular Earth orbit dynamics forming a special case. In the presence of differential solar drag perturbations, a Lyapunov feedback controller is designed to stabilize a radial equilibrium, two-craft Coulomb formation at collinear libration points. The second part of the thesis investigates optimal reconfigurations of two-craft Coulomb formations in circular Earth orbits by applying nonlinear optimal control techniques. The objective of these reconfigurations is to maneuver the two-craft formation between two charged equilibria configurations. The reconfiguration of spacecraft is posed as an optimization problem using the calculus of variations approach. The optimality criteria are minimum time, minimum acceleration of the separation distance, minimum Coulomb and electric propulsion fuel usage, and minimum electrical power consumption. The continuous time problem is discretized using a pseudospectral method, and the resulting finite dimensional problem is solved using a sequential quadratic programming algorithm. The software package, DIDO, implements this approach. This second part illustrates how pseudospectral methods significantly simplify the solution-finding process.

Possible methods for distinguishing icebergs from ships by aerial remote sensing

NASA Technical Reports Server (NTRS)

Howes, W. L.

1979-01-01

The simplest methods for aerial remote sensing which are least affected by atmospheric opacities are summarized. Radar is preferred for targets off the flight path, and microwave radiometry for targets along the flight path. Radar methods are classified by ability to resolve targets. Techniques which do not require target resolution are preferred. Among these techniques, polarization methods appear most promising, specifically those which differentiate the expected relatively greater depolarization by icebergs from that by ships or which detect doubly-reversed circular polarization.

Novel cholinesterase modulators and their ability to interact with DNA

NASA Astrophysics Data System (ADS)

Janockova, Jana; Gulasova, Zuzana; Musilek, Kamil; Kuca, Kamil; Kozurkova, Maria

2013-11-01

In the present work, an interaction of four cholinesterase modulators (1-4) with calf thymus DNA was studied via spectroscopic techniques (UV-Vis, fluorescent spectroscopy and circular dichroism). From UV-Vis spectroscopic analysis, the binding constants for DNA-pyridinium oximes complexes were calculated (K = 3.5 × 104 to 1.4 × 105 M-1). All these measurements indicated that the compounds behave as effective DNA-interacting agents. Electrophoretic techniques proved that ligand 2 inhibited topoisomerase I at a concentration 5 μM.

Magneto-optical detection of the relaxation dynamics of alloy nanoparticles with a high-stability magnetic circular dichroism setup

NASA Astrophysics Data System (ADS)

Cavigli, L.; de Julián Fernández, C.; Gatteschi, D.; Gurioli, M.; Sangregorio, C.; Mattei, G.; Mazzoldi, P.; Bogani, L.

2007-09-01

We present a versatile high-stability and high-sensitivity magneto-optical setup that allows transmission and reflection measurements at high fields and low temperatures. We apply the technique to measure the decay in time of the magnetization of highly monodisperse 3.3 nm Co33Ni67 alloy nanoparticles embedded in a silica host. We demonstrate the possibility of observing the dynamics of the magnetization over a macroscopic timescale in dilute samples, where other techniques are unavailable.

Lightweight electrical connector split backshell

NASA Technical Reports Server (NTRS)

Goldman, Elliot (Inventor)

2009-01-01

An electrical connector split backshell is provided, comprising two substantially identical backshell halves. Each half includes a first side and a cam projecting therefrom along an axis perpendicular thereto, the cam having an alignment tooth with a constant radius and an engagement section with a radius that increases with angular distance from the alignment tooth. Each half further includes a second side parallel to the first side and a circular sector opening disposed in the second side, the circular sector opening including an inner surface configured as a ramp with a constant radius, the ramp being configured to engage with an engagement section of a cam of the other half, the circular sector opening further including a relieved pocket configured to receive an alignment tooth of the cam of the other half. Each half further includes a back side perpendicular to the first and second sides and a wire bundle notch disposed in the back side, the wire bundle notch configured to align with a wire bundle notch of the other half to form a wire bundle opening. The two substantially identical halves are rotatably coupled by engaging the engagement section of each half to the ramp of the other half.

Accuracy of Estimating Highly Eccentric Binary Black Hole Parameters with Gravitational-wave Detections

NASA Astrophysics Data System (ADS)

Gondán, László; Kocsis, Bence; Raffai, Péter; Frei, Zsolt

2018-03-01

Mergers of stellar-mass black holes on highly eccentric orbits are among the targets for ground-based gravitational-wave detectors, including LIGO, VIRGO, and KAGRA. These sources may commonly form through gravitational-wave emission in high-velocity dispersion systems or through the secular Kozai–Lidov mechanism in triple systems. Gravitational waves carry information about the binaries’ orbital parameters and source location. Using the Fisher matrix technique, we determine the measurement accuracy with which the LIGO–VIRGO–KAGRA network could measure the source parameters of eccentric binaries using a matched filtering search of the repeated burst and eccentric inspiral phases of the waveform. We account for general relativistic precession and the evolution of the orbital eccentricity and frequency during the inspiral. We find that the signal-to-noise ratio and the parameter measurement accuracy may be significantly higher for eccentric sources than for circular sources. This increase is sensitive to the initial pericenter distance, the initial eccentricity, and the component masses. For instance, compared to a 30 {M}ȯ –30 {M}ȯ non-spinning circular binary, the chirp mass and sky-localization accuracy can improve by a factor of ∼129 (38) and ∼2 (11) for an initially highly eccentric binary assuming an initial pericenter distance of 20 M tot (10 M tot).

Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures: HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study.

PubMed

Kesting, Julie R; Olsen, Lars; Staerk, Dan; Tejesvi, Mysore V; Kini, Kukkundoor R; Prakash, Harishchandra S; Jaroszewski, Jerzy W

2011-10-28

The endophytic fungus Pestalotiopsis virgatula, derived from the plant Terminalia chebula and previously found to produce a large excess of a single metabolite when grown in the minimal M1D medium, was induced to produce a variety of unusual metabolites by growing in potato dextrose broth medium. Analysis of the fermentation medium extract was performed using an HPLC-PDA-MS-SPE-NMR hyphenated system, which led to the identification of a total of eight metabolites (1-8), six of which are new. Most of the metabolites are structurally related and are derivatives of benzo[c]oxepin, rare among natural products. This includes dispiro derivatives 7 and 8 (pestalospiranes A and B), having a novel 1,9,11,18-tetraoxadispiro[6.2.6.2]octadecane skeleton. Relative and absolute configurations of the latter were determined by a combination of NOESY spectroscopy and electronic circular dichroism spectroscopy supported by time-dependent density-functional theory calculations (B3LYP/TZVP level). This work demonstrates that a largely complete structure elucidation of numerous metabolites present in a raw fermentation medium extract can be performed by the HPLC-SPE-NMR technique using only a small amount of the extract, even with unstable metabolites that are difficult to isolate by traditional methods.

Travelling wave ultrasonic motor using the B08 flexural mode of a circular membrane.

PubMed

Rayner, P J; Whatmore, R W

2001-05-01

This paper describes the design, construction, and performance of a piezoelectric motor that uses the travelling B08 mode of an 80-mm diameter circular membrane to drive a rotor by frictional contact. The motor is of a thin planar design, giving high torque of up to 0.33 Nm at low speed and has been developed as a design that can be made with lithographic techniques for miniaturization. Investigations of the free stator with a vibration pattern imager and impedance analyzer gave the resonance frequency, mode, and electromechanical coupling of the stator. Motor speed as a function of frequency for a constant voltage and performance charts of speed, output power, and efficiency against torque are presented for a particular input voltage and rotor pre-load. The effects of two different lead zirconate titanate (PZT) ring dimensions have been investigated. Excitation of the B09 mode has been observed, incommensurate with the piezoelectric excitation of the stator. This is discussed with relation to edge-clamping of the stator. Single standing wave motoring was observed, believed to arise from asymmetry of the stator and its perturbation of the B08 resonance mode. Sources of power loss, including frame vibration and friction interface slip, are considered and discussed.

Cavity Exciton-Polariton mediated, Single-Shot Quantum Non-Demolition measurement of a Quantum Dot Electron Spin

NASA Astrophysics Data System (ADS)

Puri, Shruti; McMahon, Peter; Yamamoto, Yoshihisa

2014-03-01

The quantum non-demolition (QND) measurement of a single electron spin is of great importance in measurement-based quantum computing schemes. The current single-shot readout demonstrations exhibit substantial spin-flip backaction. We propose a QND readout scheme for quantum dot (QD) electron spins in Faraday geometry, which differs from previous proposals and implementations in that it relies on a novel physical mechanism: the spin-dependent Coulomb exchange interaction between a QD spin and optically-excited quantum well (QW) microcavity exciton-polaritons. The Coulomb exchange interaction causes a spin-dependent shift in the resonance energy of the polarized polaritons, thus causing the phase and intensity response of left circularly polarized light to be different to that of the right circularly polarized light. As a result the QD electron's spin can be inferred from the response to a linearly polarized probe. We show that by a careful design of the system, any spin-flip backaction can be eliminated and a QND measurement of the QD electron spin can be performed within a few 10's of nanoseconds with fidelity 99:95%. This improves upon current optical QD spin readout techniques across multiple metrics, including fidelity, speed and scalability. National Institute of Informatics, 2-1-2 Hitotsubashi, Chiyoda-ku, Tokyo 101-8430, Japan.

Robust one-Tube Ω-PCR Strategy Accelerates Precise Sequence Modification of Plasmids for Functional Genomics

PubMed Central

Chen, Letian; Wang, Fengpin; Wang, Xiaoyu; Liu, Yao-Guang

2013-01-01

Functional genomics requires vector construction for protein expression and functional characterization of target genes; therefore, a simple, flexible and low-cost molecular manipulation strategy will be highly advantageous for genomics approaches. Here, we describe a Ω-PCR strategy that enables multiple types of sequence modification, including precise insertion, deletion and substitution, in any position of a circular plasmid. Ω-PCR is based on an overlap extension site-directed mutagenesis technique, and is named for its characteristic Ω-shaped secondary structure during PCR. Ω-PCR can be performed either in two steps, or in one tube in combination with exonuclease I treatment. These strategies have wide applications for protein engineering, gene function analysis and in vitro gene splicing. PMID:23335613

Correction of Dual-PRF Doppler Velocity Outliers in the Presence of Aliasing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Altube, Patricia; Bech, Joan; Argemí, Oriol

In Doppler weather radars, the presence of unfolding errors or outliers is a well-known quality issue for radial velocity fields estimated using the dual–pulse repetition frequency (PRF) technique. Postprocessing methods have been developed to correct dual-PRF outliers, but these need prior application of a dealiasing algorithm for an adequate correction. Our paper presents an alternative procedure based on circular statistics that corrects dual-PRF errors in the presence of extended Nyquist aliasing. The correction potential of the proposed method is quantitatively tested by means of velocity field simulations and is exemplified in the application to real cases, including severe storm events.more » The comparison with two other existing correction methods indicates an improved performance in the correction of clustered outliers. The technique we propose is well suited for real-time applications requiring high-quality Doppler radar velocity fields, such as wind shear and mesocyclone detection algorithms, or assimilation in numerical weather prediction models.« less

High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer’s disease

PubMed Central

Plascencia-Villa, Germán; Ponce, Arturo; Collingwood, Joanna F.; Arellano-Jiménez, M. Josefina; Zhu, Xiongwei; Rogers, Jack T.; Betancourt, Israel; José-Yacamán, Miguel; Perry, George

2016-01-01

Abnormal accumulation of brain metals is a key feature of Alzheimer’s disease (AD). Formation of amyloid-β plaque cores (APC) is related to interactions with biometals, especially Fe, Cu and Zn, but their particular structural associations and roles remain unclear. Using an integrative set of advanced transmission electron microscopy (TEM) techniques, including spherical aberration-corrected scanning transmission electron microscopy (Cs-STEM), nano-beam electron diffraction, electron holography and analytical spectroscopy techniques (EDX and EELS), we demonstrate that Fe in APC is present as iron oxide (Fe3O4) magnetite nanoparticles. Here we show that Fe was accumulated primarily as nanostructured particles within APC, whereas Cu and Zn were distributed through the amyloid fibers. Remarkably, these highly organized crystalline magnetite nanostructures directly bound into fibrillar Aβ showed characteristic superparamagnetic responses with saturated magnetization with circular contours, as observed for the first time by off-axis electron holography of nanometer scale particles. PMID:27121137

New is the well-forgotten old: The use of dry cupping in musculoskeletal medicine.

PubMed

Rozenfeld, Evgeni; Kalichman, Leonid

2016-01-01

Cupping is an ancient technique used in treating pain and various disorders. Different techniques have been developed over time, however, applying a cup to create suction over a painful area, is common to all. Dry or fire cupping, used on the intact skin, leaves bluish circular hematomas. Recently, interest in cupping has re-emerged and subsequently, several studies have begun to investigate the mechanisms of cupping therapy. Mechanically, cupping increases blood circulation, whereas physiologically it activates the immune system and stimulates the mechanosensitive fibers, thus leading to a reduction in pain. There is initial scientific evidence that dry cupping is able to reduce musculoskeletal pain. Since cupping is an inexpensive, noninvasive and low-risk (if performed by a trained practitioner) therapeutic modality, we believe that it should be included in the arsenal of musculoskeletal medicine. It is essential to perform additional studies clarifying the biological mechanism and clinical effects of cupping. Copyright © 2015 Elsevier Ltd. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Afzal, Muhammad U., E-mail: muhammad.afzal@mq.edu.au; Esselle, Karu P.

This paper presents a quasi-analytical technique to design a continuous, all-dielectric phase correcting structures (PCSs) for circularly polarized Fabry-Perot resonator antennas (FPRAs). The PCS has been realized by varying the thickness of a rotationally symmetric dielectric block placed above the antenna. A global analytical expression is derived for the PCS thickness profile, which is required to achieve nearly uniform phase distribution at the output of the PCS, despite the non-uniform phase distribution at its input. An alternative piecewise technique based on spline interpolation is also explored to design a PCS. It is shown from both far- and near-field results thatmore » a PCS tremendously improves the radiation performance of the FPRA. These improvements include an increase in peak directivity from 22 to 120 (from 13.4 dBic to 20.8 dBic) and a decrease of 3 dB beamwidth from 41.5° to 15°. The phase-corrected antenna also has a good directivity bandwidth of 1.3 GHz, which is 11% of the center frequency.« less

High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer’s disease

NASA Astrophysics Data System (ADS)

Plascencia-Villa, Germán; Ponce, Arturo; Collingwood, Joanna F.; Arellano-Jiménez, M. Josefina; Zhu, Xiongwei; Rogers, Jack T.; Betancourt, Israel; José-Yacamán, Miguel; Perry, George

2016-04-01

Abnormal accumulation of brain metals is a key feature of Alzheimer’s disease (AD). Formation of amyloid-β plaque cores (APC) is related to interactions with biometals, especially Fe, Cu and Zn, but their particular structural associations and roles remain unclear. Using an integrative set of advanced transmission electron microscopy (TEM) techniques, including spherical aberration-corrected scanning transmission electron microscopy (Cs-STEM), nano-beam electron diffraction, electron holography and analytical spectroscopy techniques (EDX and EELS), we demonstrate that Fe in APC is present as iron oxide (Fe3O4) magnetite nanoparticles. Here we show that Fe was accumulated primarily as nanostructured particles within APC, whereas Cu and Zn were distributed through the amyloid fibers. Remarkably, these highly organized crystalline magnetite nanostructures directly bound into fibrillar Aβ showed characteristic superparamagnetic responses with saturated magnetization with circular contours, as observed for the first time by off-axis electron holography of nanometer scale particles.

Correction of Dual-PRF Doppler Velocity Outliers in the Presence of Aliasing

DOE PAGES

Altube, Patricia; Bech, Joan; Argemí, Oriol; ...

2017-07-18

In Doppler weather radars, the presence of unfolding errors or outliers is a well-known quality issue for radial velocity fields estimated using the dual–pulse repetition frequency (PRF) technique. Postprocessing methods have been developed to correct dual-PRF outliers, but these need prior application of a dealiasing algorithm for an adequate correction. Our paper presents an alternative procedure based on circular statistics that corrects dual-PRF errors in the presence of extended Nyquist aliasing. The correction potential of the proposed method is quantitatively tested by means of velocity field simulations and is exemplified in the application to real cases, including severe storm events.more » The comparison with two other existing correction methods indicates an improved performance in the correction of clustered outliers. The technique we propose is well suited for real-time applications requiring high-quality Doppler radar velocity fields, such as wind shear and mesocyclone detection algorithms, or assimilation in numerical weather prediction models.« less

The use of bioabsorbable staple line reinforcement for circular stapler (BSG "Seamguard") in colorectal surgery: initial experience.

PubMed

Franklin, Morris E; Ramila, Guillermo Portillo; Treviño, Jorge M; González, John J; Russek, Karla; Glass, Jeffrey L; Kim, Greg

2006-12-01

Of all the complications associated with colorectal surgery, the most devastating and constant, despite all techniques being performed properly is anastomotic leakage, especially in left colon and rectal resections with rates as high as 50% when the rectum is involved. In 2005, our center published the preliminary experience with the use of linear staple line reinforcement for colon surgery. The purpose of this paper is to present a series of cases using a new conformation of bioabsorbable reinforcement for circular staplers in 5 patients, 2 patients with rectal cancer, 2 patients with diverticular disease, and 1 patient with sigmoid cancer. These initial data are very promising and has encouraged us to continue using this device on further patients.

The endoventricular circular patch plasty ("Dor procedure") in ischemic akinetic dilated ventricles.

PubMed

Dor, V

2001-09-01

From 1984 to 2000, 950 Left Ventricular ischemic asynergy (dyskinetic or akinetic) were operated using the endoventricular circular patch plasty technique. This allows to exclude all asynergic areas of the left ventricular wall and reshape the remaining wall. Both morphology and hemodynamic of left ventricle, are improved. Hospital mortality was below 7%. Life expectancy at 10 years reaches 80% if pre-operative L.V.E.F. is above 30%, and end systolic volume index (E.S.V.I.) below 90[emsp4 ]ml, and 60% in L.V.E.F. is below 30% and E.S.V.I. above 90[emsp4 ]ml. L.V.R. by endoventricular plasty has to be considered in the treatment of ischemic congestive heart failure.

Tomographic determination of the power distribution in electron beams

DOEpatents

Teruya, Alan T.; Elmer, John W.

1996-01-01

A tomographic technique for determining the power distribution of an electron beam using electron beam profile data acquired from a modified Faraday cup to create an image of the current density in high and low power beams. A refractory metal disk with a number of radially extending slits is placed above a Faraday cup. The beam is swept in a circular pattern so that its path crosses each slit in a perpendicular manner, thus acquiring all the data needed for a reconstruction in one circular sweep. Also, a single computer is used to generate the signals actuating the sweep, to acquire that data, and to do the reconstruction, thus reducing the time and equipment necessary to complete the process.

Tomographic determination of the power distribution in electron beams

DOEpatents

Teruya, A.T.; Elmer, J.W.

1996-12-10

A tomographic technique for determining the power distribution of an electron beam using electron beam profile data acquired from a modified Faraday cup to create an image of the current density in high and low power beams is disclosed. A refractory metal disk with a number of radially extending slits is placed above a Faraday cup. The beam is swept in a circular pattern so that its path crosses each slit in a perpendicular manner, thus acquiring all the data needed for a reconstruction in one circular sweep. Also, a single computer is used to generate the signals actuating the sweep, to acquire that data, and to do the reconstruction, thus reducing the time and equipment necessary to complete the process. 4 figs.

Linkage Map of Escherichia coli K-12, Edition 10: The Traditional Map

PubMed Central

Berlyn, Mary K. B.

1998-01-01

This map is an update of the edition 9 map by Berlyn et al. (M. K. B. Berlyn, K. B. Low, and K. E. Rudd, p. 1715–1902, in F. C. Neidhardt et al., ed., Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed., vol. 2, 1996). It uses coordinates established by the completed sequence, expressed as 100 minutes for the entire circular map, and adds new genes discovered and established since 1996 and eliminates those shown to correspond to other known genes. The latter are included as synonyms. An alphabetical list of genes showing map location, synonyms, the protein or RNA product of the gene, phenotypes of mutants, and reference citations is provided. In addition to genes known to correspond to gene sequences, other genes, often older, that are described by phenotype and older mapping techniques and that have not been correlated with sequences are included. PMID:9729611

Elasto-plastic bending of cracked plates, including the effects of crack closure. Ph.D. Thesis

NASA Technical Reports Server (NTRS)

Jones, D. P.

1972-01-01

A capability for solving elasto-plastic plate bending problems is developed using assumptions consistent with Kirchhoff plate theory. Both bending and extensional modes of deformation are admitted with the two modes becoming coupled as yielding proceeds. Equilibrium solutions are obtained numerically by determination of the stationary point of a functional which is analogous to the potential strain energy. The stationary value of the functional for each load increment is efficiently obtained through use of the conjugate gradient. This technique is applied to the problem of a large centrally through cracked plate subject to remote circular bending. Comparison is drawn between two cases of the bending problem. The first neglects the possibility of crack face interference with bending, and the second includes a kinematic prohibition against the crack face from passing through the symmetry plane. Results are reported which isolate the effects of elastoplastic flow and crack closure.

Modal analysis applied to circular, rectangular, and coaxial waveguides

NASA Technical Reports Server (NTRS)

Hoppe, D. J.

1988-01-01

Recent developments in the analysis of various waveguide components and feedhorns using Modal Analysis (Mode Matching Method) are summarized. A brief description of the theory is presented, and the important features of the method are pointed out. Specific examples in circular, rectangular, and coaxial waveguides are included, with comparisons between the theory and experimental measurements. Extensions to the methods are described.

Soil and land management in a circular economy.

PubMed

Breure, A M; Lijzen, J P A; Maring, L

2018-05-15

This article elaborates the role of soil and land management in a circular economy. The circular economy is highly dependent on the functioning of soils and land for the production of food and other biomass; the storage, filtration and transformation of many substances including water, carbon, and nitrogen; the provision of fresh mineral resources and fossil fuels; and the use of their functions as the platform for nature and human activities. Resource demand is increasing as a result of the growing human population. In addition to the shrinking availability of resources resulting from their unsustainable use in the past, our planet's diminishing potential for resource production, due to a range of reasons, is leading to resource scarcity, especially in the case of depletable resources. As an economic system that focuses on maximizing the reuse of resources and products and minimizing their depreciation, the circular economy greatly influences, and depends on, soil and land management. The concise management of the resources, land and soil is thus necessary, to make a circular economy successful. Copyright © 2017 Elsevier B.V. All rights reserved.

Probabilistic properties of the date of maximum river flow, an approach based on circular statistics in lowland, highland and mountainous catchment

NASA Astrophysics Data System (ADS)

Rutkowska, Agnieszka; Kohnová, Silvia; Banasik, Kazimierz

2018-04-01

Probabilistic properties of dates of winter, summer and annual maximum flows were studied using circular statistics in three catchments differing in topographic conditions; a lowland, highland and mountainous catchment. The circular measures of location and dispersion were used in the long-term samples of dates of maxima. The mixture of von Mises distributions was assumed as the theoretical distribution function of the date of winter, summer and annual maximum flow. The number of components was selected on the basis of the corrected Akaike Information Criterion and the parameters were estimated by means of the Maximum Likelihood method. The goodness of fit was assessed using both the correlation between quantiles and a version of the Kuiper's and Watson's test. Results show that the number of components varied between catchments and it was different for seasonal and annual maxima. Differences between catchments in circular characteristics were explained using climatic factors such as precipitation and temperature. Further studies may include circular grouping catchments based on similarity between distribution functions and the linkage between dates of maximum precipitation and maximum flow.

Spin relaxation dynamics of holes in intrinsic GaAs quantum wells studied by transient circular dichromatic absorption spectroscopy at room temperature.

PubMed

Fang, Shaoyin; Zhu, Ruidan; Lai, Tianshu

2017-03-21

Spin relaxation dynamics of holes in intrinsic GaAs quantum wells is studied using time-resolved circular dichromatic absorption spectroscopy at room temperature. It is found that ultrafast dynamics is dominated by the cooperative contributions of band filling and many-body effects. The relative contribution of the two effects is opposite in strength for electrons and holes. As a result, transient circular dichromatic differential transmission (TCD-DT) with co- and cross-circularly polarized pump and probe presents different strength at several picosecond delay time. Ultrafast spin relaxation dynamics of excited holes is sensitively reflected in TCD-DT with cross-circularly polarized pump and probe. A model, including coherent artifact, thermalization of nonthermal carriers and the cooperative contribution of band filling and many-body effects, is developed, and used to fit TCD-DT with cross-circularly polarized pump and probe. Spin relaxation time of holes is achieved as a function of excited hole density for the first time at room temperature, and increases with hole density, which disagrees with a theoretical prediction based on EY spin relaxation mechanism, implying that EY mechanism may be not dominant hole spin relaxation mechanism at room temperature, but DP mechanism is dominant possibly.

Novel Gas Sensor Based on ZnO Nanorod Circular Arrays for C2H5OH Gas Detection.

PubMed

Jianjiao, Zhang; Hongyan, Yue; Erjun, Guo; Shaolin, Zhang; Liping, Wang; Chunyu, Zhang; Xin, Gao; Jing, Chang; Hong, Zhang

2015-03-01

Novel side-heating gas sensor based on ZnO nanorod circular arrays was firstly fabricated by hydrothermal treatment assisted with a kind of simple dip-coating technique. The structure and morphologies of ZnO nanorods were characterized by X-ray diffraction (XRD), Scanning Electron Microscope (SEM), respectively. XRD result indicates that the obtained ZnO nanorods have good crystalline with the hexagonal wurtzite structure. SEM result indicates that ZnO nanorod arrays are vertically growth on the surface of ceramic tube of side-heating sensor with controlled diameter and length, narrow size distribution and high orientation. The gas sensing properties of ZnO nanorod circular arrays are also evaluated. Comparative to the sensor based on scattered ZnO nanorods responding to 25 ppm H2, CO, C6H5CH3 and C2H5OH gas, respectively, the sensing values of high orientation gas sensor are generally increased by 5%. This novel sensor has good application promising for the fabrication of cost effective and high performance gas sensors.

Strong circular dichroism in a non-chiral metasurface based on an array of metallic V-shaped nanostructures

NASA Astrophysics Data System (ADS)

Ardakani, Abbas Ghasempour; Moradi, Khatereh

2018-02-01

In this paper, an extrinsic chiral metasurface based on a silver thin film containing a periodic array of V-shaped nanostructures is proposed. The proposed structure is normally and obliquely illuminated by right- and left-handed circularly polarized plane waves and the transmission through the structure is calculated using the frequency domain finite-integration technique. Our simulation results show that the designed metasurface exhibits strong circular dichroism (CD) in the transmission Δ = T_{RCP}- T_{LCP}=0.98 in the near-infrared region under oblique incidence. To our knowledge, this is one of highest CD effects that have been achieved so far in the single-layer metasurface based on metallic nanostructures. The physical mechanism for this strong CD effect is explained in terms of the current density distribution. Furthermore, the effects of change of the incident angle, the refractive index of surrounding medium and structure parameters, such as film thickness and lattice constants on CD spectrum, are investigated. In addition, the CD phenomenon in the structure is analyzed in other frequency regions.

Dynamic Fluid in a Porous Transducer-Based Angular Accelerometer

PubMed Central

Cheng, Siyuan; Fu, Mengyin; Wang, Meiling; Ming, Li; Fu, Huijin; Wang, Tonglei

2017-01-01

This paper presents a theoretical model of the dynamics of liquid flow in an angular accelerometer comprising a porous transducer in a circular tube of liquid. Wave speed and dynamic permeability of the transducer are considered to describe the relation between angular acceleration and the differential pressure on the transducer. The permeability and streaming potential coupling coefficient of the transducer are determined in the experiments, and special prototypes are utilized to validate the theoretical model in both the frequency and time domains. The model is applied to analyze the influence of structural parameters on the frequency response and the transient response of the fluidic system. It is shown that the radius of the circular tube and the wave speed affect the low frequency gain, as well as the bandwidth of the sensor. The hydrodynamic resistance of the transducer and the cross-section radius of the circular tube can be used to control the transient performance. The proposed model provides the basic techniques to achieve the optimization of the angular accelerometer together with the methodology to control the wave speed and the hydrodynamic resistance of the transducer. PMID:28230793

Circular dichroism of magnetically induced transitions for D2 lines of alkali atoms

NASA Astrophysics Data System (ADS)

Tonoyan, A.; Sargsyan, A.; Klinger, E.; Hakhumyan, G.; Leroy, C.; Auzinsh, M.; Papoyan, A.; Sarkisyan, D.

2018-03-01

In this letter we study magnetic circular dichroism in alkali atoms exhibiting asymmetric behaviour of magnetically induced transitions. The magnetic field \\textbf{B}\\parallel\\textbf{k} induces transitions between Δ F = +/-2 hyperfine levels of alkali atoms and in the range of ∼0.1{\\text{--}}3 \\text{kG} magnetic field, the intensities of these transitions experience significant enhancement. We have inferred a general rule applicable for the D 2 lines of all alkali atoms, that is the transition intensity enhancement is around four times larger for the case of σ+ than for σ- excitation for Δ F = +2 , whereas it is several hundreds of thousand times larger in the case of σ- than that for σ+ polarization for Δ F = -2 . This asymmetric behaviour results in circular dichroism. For experimental verification we employed half-wavelength-thick atomic vapor nanocells using a derivative of the selective reflection technique, which provides a sub-Doppler spectroscopic linewidth (∼50 \\text{MHz} ). The presented theoretical curves well describe the experimental results. This effect can find applications particularly in parity violation experiments.

Nonplanar Method for Predicting Incompressible Aerodynamic Coefficients of Rectangular Wings with Circular-Arc Camber. Ph.D. Thesis - Virginia Polytechnic Institute

NASA Technical Reports Server (NTRS)

Lamar, J. E.

1971-01-01

The development of a nonplanar lifting surface method having a continuous distribution of singularities and satisfying the tangent flow boundary condition on the mean camber surface is given. The method predicts some incompressible longitudinal aerodynamic coefficients of rectangular wings which have circular-arc camber. The solution method is of the integral-equation type and the resulting surface integrals are evaluated by either using numerical or analytical techniques, as are appropriate. Applications are made and the results compared with those from an exact two-dimensional circular-arc camber solution, a three-dimensional flat-wing solution which represents the camber by a projected slope onto the flat surface, and a flat-wing experiment. From these comparisons, the present method is found to predict well the flat-wing experiment and limiting values, in addition to the center of pressure variation at an angle of attack of zero for any camber. For wings having camber ratios larger than about 1.25% and moderate to high aspect ratios, the results deterioriate due to the inadequacy of lifting pressure modes employed.

Laser mass spectrometry with circularly polarized light: circular dichroism of cold molecules in a supersonic gas beam.

PubMed

Titze, Katharina; Zollitsch, Tilo; Heiz, Ulrich; Boesl, Ulrich

2014-09-15

An experiment on chiral molecules that combines circular dichroism (CD) spectroscopy, mass-selective detection by laser mass spectrometry (MS), and cooling of molecules by using a supersonic beam is presented. The combination of the former two techniques (CD-laser-MS) is a new method to investigate chiral molecules and is now used by several research groups. Cooling in a supersonic beam supplies a substantial increase in spectroscopic resolution, a feature that has not yet been used in CD spectroscopy. In the experiments reported herein, a large variation in the electronic CD of carbonyl 3-methylcyclopentanone was observed depending on the excited vibrational modes in the n → π* transition. This finding should be of interest for the detection of chiral molecules and for the theoretical understanding of the CD of vibronic bands. It is expected that this effect will show up in other chiral carbonyls because the n → π* transition is typical for the carbonyl group. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Theoretical and numerical evaluation of polarimeter using counter-circularly-polarized-probing-laser under the coupling between Faraday and Cotton-Mouton effect.

PubMed

Imazawa, Ryota; Kawano, Yasunori; Itami, Kiyoshi

2016-04-01

This study evaluated an effect of an coupling between the Faraday and Cotton-Mouton effect to a measurement signal of the Dodel-Kunz method which uses counter-circular-polarized probing-laser for measuring the Faraday effect. When the coupling is small (the Faraday effect is dominant and the characteristic eigenmodes are approximately circularly polarized), the measurement signal can be algebraically expressed and it is shown that the finite effect of the coupling is still significant. When the Faraday effect is not dominant, a numerical calculation is necessary. The numerical calculation under an ITER-like condition (Bt = 5.3 T, Ip = 15 MA, a = 2 m, ne = 10(20) m(-3) and λ = 119 μm) showed that difference between the pure Faraday rotation and the measurement signal of the Dodel-Kunz method was an order of one degree, which exceeds allowable error of ITER poloidal polarimeter. In conclusion, similar to other polarimeter techniques, the Dodel-Kunz method is not free from the coupling between the Faraday and Cotton-Mouton effect.

Comparing the Performance of Hyperbolic and Circular Rod Quadrupole Mass Spectrometers with Applied Higher Order Auxiliary Excitation

NASA Technical Reports Server (NTRS)

Gershman, D.J.; Block, B.P.; Rubin, M.; Benna, M.; Mahaffy, P. R.; Zurbuchen, T. H.

2012-01-01

This work applies higher order auxiliary excitation techniques to two types of quadrupole mass spectrometers (QMSs): commercial systems and spaceborne instruments. The operational settings of a circular rod geometry commercial system and an engineering test-bed for a hyperbolic rod geometry spaceborne instrument were matched, with the relative performance of each sensor characterized with and without applied excitation using isotopic measurements of Kr+. Each instrument was operated at the limit of the test electronics to determine the effect of auxiliary excitation on extending instrument capabilities. For the circular rod sensor, with applied excitation, a doubling of the mass resolution at 1% of peak transmission resulted from the elimination of the low-mass side peak tail typical of such rod geometries. The mass peak stability and ion rejection efficiency were also increased by factors of 2 and 10, respectively, with voltage scan lines passing through the center of stability islands formed from auxiliary excitation. Auxiliary excitation also resulted in factors of 6 and 2 in peak stability and ion rejection efficiency, respectively, for the hyperbolic rod sensor. These results not only have significant implications for the use of circular rod quadrupoles with applied excitation as a suitable replacement for traditional hyperbolic rod sensors, but also for extending the capabilities of existing hyperbolic rod QMSs for the next generation of spaceborne instruments and low-mass commercial systems.

An experimental extrapolation technique using the Gafchromic EBT3 film for relative output factor measurements in small x-ray fields

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morales, Johnny E., E-mail: johnny.morales@lh.org.

Purpose: An experimental extrapolation technique is presented, which can be used to determine the relative output factors for very small x-ray fields using the Gafchromic EBT3 film. Methods: Relative output factors were measured for the Brainlab SRS cones ranging in diameters from 4 to 30 mm{sup 2} on a Novalis Trilogy linear accelerator with 6 MV SRS x-rays. The relative output factor was determined from an experimental reducing circular region of interest (ROI) extrapolation technique developed to remove the effects of volume averaging. This was achieved by scanning the EBT3 film measurements with a high scanning resolution of 1200 dpi.more » From the high resolution scans, the size of the circular regions of interest was varied to produce a plot of relative output factors versus area of analysis. The plot was then extrapolated to zero to determine the relative output factor corresponding to zero volume. Results: Results have shown that for a 4 mm field size, the extrapolated relative output factor was measured as a value of 0.651 ± 0.018 as compared to 0.639 ± 0.019 and 0.633 ± 0.021 for 0.5 and 1.0 mm diameter of analysis values, respectively. This showed a change in the relative output factors of 1.8% and 2.8% at these comparative regions of interest sizes. In comparison, the 25 mm cone had negligible differences in the measured output factor between zero extrapolation, 0.5 and 1.0 mm diameter ROIs, respectively. Conclusions: This work shows that for very small fields such as 4.0 mm cone sizes, a measureable difference can be seen in the relative output factor based on the circular ROI and the size of the area of analysis using radiochromic film dosimetry. The authors recommend to scan the Gafchromic EBT3 film at a resolution of 1200 dpi for cone sizes less than 7.5 mm and to utilize an extrapolation technique for the output factor measurements of very small field dosimetry.« less

Diffusion of isolated DNA molecules: dependence on length and topology.

PubMed

Robertson, Rae M; Laib, Stephan; Smith, Douglas E

2006-05-09

The conformation and dynamics of circular polymers is a subject of considerable theoretical and experimental interest. DNA is an important example because it occurs naturally in different topological states, including linear, relaxed circular, and supercoiled circular forms. A fundamental question is how the diffusion coefficients of isolated polymers scale with molecular length and how they vary for different topologies. Here, diffusion coefficients D for relaxed circular, supercoiled, and linear DNA molecules of length L ranging from approximately 6 to 290 kbp were measured by tracking the Brownian motion of single molecules. A topology-independent scaling law D approximately L(-nu) was observed with nu(L) = 0.571 +/- 0.014, nu(C) = 0.589 +/- 0.018, and nu(S) = 0.571 +/- 0.057 for linear, relaxed circular, and supercoiled DNA, respectively, in good agreement with the scaling exponent of nu congruent with 0.588 predicted by renormalization group theory for polymers with significant excluded volume interactions. Our findings thus provide evidence in support of several theories that predict an effective diameter of DNA much greater than the Debye screening length. In addition, the measured ratio D(Circular)/D(Linear) = 1.32 +/- 0.014 was closer to the value of 1.45 predicted by using renormalization group theory than the value of 1.18 predicted by classical Kirkwood hydrodynamic theory and agreed well with a value of 1.31 predicted when incorporating a recently proposed expression for the radius of gyration of circular polymers into the Zimm model.

Antimicrobial preservative use in parenteral products: past and present.

PubMed

Meyer, Brian K; Ni, Alex; Hu, Binghua; Shi, Li

2007-12-01

The following review provides a comprehensive summary of antimicrobial preservatives that are commonly used in licensed parenteral products to date. The information reviewed includes the general properties of the preservatives, the doses and frequency of their use, the classes of the preserved products (peptide, protein, vaccine, and small molecule products), the interactions with other formulation components, and the criteria commonly used for their selection in parental product formulations. It was revealed that phenol and benzyl alcohol are the two most common antimicrobial preservatives used in peptide and protein products, while phenoxyethanol is the most frequently used preservative in vaccines. Benzyl alcohol or a combination of methylparaben and propylparaben are generally found in small molecule parenteral formulations. The key criteria for antimicrobial preservative selection are the preservative's dose, antimicrobial functionality, and effect on the active ingredient. Additionally, the use of spectroscopic techniques (circular dicroism (CD) and fluorescence) and differential scanning calorimetry (DSC) were identified as common techniques used in evaluating an antimicrobial preservative for its impact on the conformational stability of peptide, protein, and vaccine antigens. The future use of preservatives is also discussed, including antimicrobial agents such as peptides, and regulatory requirements for antimicrobial effectiveness testing. (c) 2007 Wiley-Liss, Inc.

Circular Dichroism Spectroscopy: Enhancing a Traditional Undergraduate Biochemistry Laboratory Experience

ERIC Educational Resources Information Center

Lewis, Russell L.; Seal, Erin L.; Lorts, Aimee R.; Stewart, Amanda L.

2017-01-01

The undergraduate biochemistry laboratory curriculum is designed to provide students with experience in protein isolation and purification protocols as well as various data analysis techniques, which enhance the biochemistry lecture course and give students a broad range of tools upon which to build in graduate level laboratories or once they…

Strategic family therapy interventions with deaf member families.

PubMed

Sloman, L; Springer, S

1987-10-01

A deviance based model of deafness is compared with one based on ethnicity. The function of inadequate communication in deaf member families is explored. Techniques of intervention are examined with a focus on three strategic interventions namely: 1) circular interviewing; 2) positive connotation; and, 3) use of rituals. Case histories are provided.

A Simple Demonstration of Atomic and Molecular Orbitals Using Circular Magnets

ERIC Educational Resources Information Center

Chakraborty, Maharudra; Mukhopadhyay, Subrata; Das, Ranendu Sekhar

2014-01-01

A quite simple and inexpensive technique is described here to represent the approximate shapes of atomic orbitals and the molecular orbitals formed by them following the principles of the linear combination of atomic orbitals (LCAO) method. Molecular orbitals of a few simple molecules can also be pictorially represented. Instructors can employ the…

Waste Management, Treatment, and Disposal for the Food Processing Industry. Special Circular 113.

ERIC Educational Resources Information Center

Wooding, N. Henry

This publication contains information relating to waste prevention, treatment and disposal, and waste product utilization. Its primary purpose is to provide information that will help the food industry executive recognize waste problems and make wise management decisions. The discussion of the methods, techniques, and the state-of-the-art is…

Revolving Eddy-Current Probe Detects Cracks Near Rivets

NASA Technical Reports Server (NTRS)

Namkung, Min; Wincheski, Buzz; Fulton, James P.; Nath, Shridhar; Simpson, John

1995-01-01

Scanning eddy-current probe in circular pattern increases sensitivity with which probe indicates fatigue cracks and other defects in metal surfaces in vicinity of rivets. Technique devised to facilitate inspection of riveted joints in aircraft. Eddy-current probe in question described in "Electro-magnetic Flaw Detector Is Easier To Use" (LAR-15046).

Imidazolium tagged acridines: Synthesis, characterization and applications in DNA binding and anti-microbial activities

NASA Astrophysics Data System (ADS)

Raju, Gembali; Vishwanath, S.; Prasad, Archana; Patel, Basant K.; Prabusankar, Ganesan

2016-03-01

New water soluble 4,5-bis imidazolium tagged acridines have been synthesized and structurally characterized by multinuclear NMR and single crystal X-ray diffraction techniques. The DNA binding and anti-microbial activities of these acridine derivatives were investigated by fluorescence and far-UV circular dichroism studies.

Mass transfer from a circular cylinder: Effects of flow unsteadiness and slight nonuniformities

NASA Technical Reports Server (NTRS)

Marziale, M. L.; Mayle, R. E.

1984-01-01

Experiments were performed to determine the effect of periodic variations in the angle of the flow incident to a turbine blade on its leading edge heat load. To model this situation, measurements were made on a circular cylinder oscillating rotationally in a uniform steady flow. A naphthalene mass transfer technique was developed and used in the experiments and heat transfer rates are inferred from the results. The investigation consisted of two parts. In the first, a stationary cylinder was used and the transfer rate was measured for Re = 75,000 to 110,000 and turbulence levels from .34 percent to 4.9 percent. Comparisons with both theory and the results of others demonstrate that the accuracy and repeatability of the developed mass transfer technique is about + or - 2 percent, a large improvement over similar methods. In the second part identical flow conditions were used but the cylinder was oscillated. A Strouhal number range from .0071 to .1406 was covered. Comparisons of the unsteady and steady results indicate that the magnitude of the effect of oscillation is small and dependent on the incident turbulence conditions.

A general way for quantitative magnetic measurement by transmitted electrons

NASA Astrophysics Data System (ADS)

Song, Dongsheng; Li, Gen; Cai, Jianwang; Zhu, Jing

2016-01-01

EMCD (electron magnetic circular dichroism) technique opens a new door to explore magnetic properties by transmitted electrons. The recently developed site-specific EMCD technique makes it possible to obtain rich magnetic information from the Fe atoms sited at nonequivalent crystallographic planes in NiFe2O4, however it is based on a critical demand for the crystallographic structure of the testing sample. Here, we have further improved and tested the method for quantitative site-specific magnetic measurement applicable for more complex crystallographic structure by using the effective dynamical diffraction effects (general routine for selecting proper diffraction conditions, making use of the asymmetry of dynamical diffraction for design of experimental geometry and quantitative measurement, etc), and taken yttrium iron garnet (Y3Fe5O12, YIG) with more complex crystallographic structure as an example to demonstrate its applicability. As a result, the intrinsic magnetic circular dichroism signals, spin and orbital magnetic moment of iron with site-specific are quantitatively determined. The method will further promote the development of quantitative magnetic measurement with high spatial resolution by transmitted electrons.

Thin-plate spline quadrature of geodetic integrals

NASA Technical Reports Server (NTRS)

Vangysen, Herman

1989-01-01

Thin-plate spline functions (known for their flexibility and fidelity in representing experimental data) are especially well-suited for the numerical integration of geodetic integrals in the area where the integration is most sensitive to the data, i.e., in the immediate vicinity of the evaluation point. Spline quadrature rules are derived for the contribution of a circular innermost zone to Stoke's formula, to the formulae of Vening Meinesz, and to the recursively evaluated operator L(n) in the analytical continuation solution of Molodensky's problem. These rules are exact for interpolating thin-plate splines. In cases where the integration data are distributed irregularly, a system of linear equations needs to be solved for the quadrature coefficients. Formulae are given for the terms appearing in these equations. In case the data are regularly distributed, the coefficients may be determined once-and-for-all. Examples are given of some fixed-point rules. With such rules successive evaluation, within a circular disk, of the terms in Molodensky's series becomes relatively easy. The spline quadrature technique presented complements other techniques such as ring integration for intermediate integration zones.

Damage evaluation of fiber reinforced plastic-confined circular concrete-filled steel tubular columns under cyclic loading using the acoustic emission technique

NASA Astrophysics Data System (ADS)

Li, Dongsheng; Du, Fangzhu; Ou, Jinping

2017-03-01

Glass-fiber reinforced plastic (GFRP)-confined circular concrete-filled steel tubular (CCFT) columns comprise of concrete, steel, and GFRP and show complex failure mechanics under cyclic loading. This paper investigated the failure mechanism and damage evolution of GFRP-CCFT columns by performing uniaxial cyclic loading tests that were monitored using the acoustic emission (AE) technique. Characteristic AE parameters were obtained during the damage evolution of GFRP-CCFT columns. Based on the relationship between the loading curve and these parameters, the damage evolution of GFRP-CCFT columns was classified into three stages that represented different damage degrees. Damage evolution and failure mode were investigated by analyzing the b-value and the ratio of rise time to waveform amplitude and average frequency. The damage severity of GFRP-CCFT columns were quantitatively estimated according to the modified index of damage and NDIS-2421 damage assessment criteria corresponding to each loading step. The proposed method can explain the damage evolution and failure mechanism for GFRP-CCFT columns and provide critical warning information for composite structures.

Detecting the optic disc boundary in digital fundus images using morphological, edge detection, and feature extraction techniques.

PubMed

Aquino, Arturo; Gegundez-Arias, Manuel Emilio; Marin, Diego

2010-11-01

Optic disc (OD) detection is an important step in developing systems for automated diagnosis of various serious ophthalmic pathologies. This paper presents a new template-based methodology for segmenting the OD from digital retinal images. This methodology uses morphological and edge detection techniques followed by the Circular Hough Transform to obtain a circular OD boundary approximation. It requires a pixel located within the OD as initial information. For this purpose, a location methodology based on a voting-type algorithm is also proposed. The algorithms were evaluated on the 1200 images of the publicly available MESSIDOR database. The location procedure succeeded in 99% of cases, taking an average computational time of 1.67 s. with a standard deviation of 0.14 s. On the other hand, the segmentation algorithm rendered an average common area overlapping between automated segmentations and true OD regions of 86%. The average computational time was 5.69 s with a standard deviation of 0.54 s. Moreover, a discussion on advantages and disadvantages of the models more generally used for OD segmentation is also presented in this paper.

Size-dependent quantum diffusion of Gd atoms within Fe nano-corrals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hu, J.; Cao, R. X.; Miao, B. F.

2013-12-01

We systematically studied the size-dependent quantum diffusion of Gd atoms within Fe circular quantum corrals on Ag(111). By varying the size of the quantum corrals, different types of patterns are observed inside the corrals, including a single dot and circular orbits for the diffusion of Gd adatoms. In addition, the motion of the adatoms also forms circular-like orbits outside the corral. Via quantitative analysis, we confirm that the regions with adatoms' high visiting probability are consistent with the positions of the local electronic density-of-states maxima, both inside and outside the corrals within a < 0.2 nm offset. The results agreemore » well with kinetic Monte Carlo simulations that utilize the experimentally determined interaction between Gd and Fe circular corrals. These findings demonstrate that one can engineer adatom motion by controlling the size of the quantum corrals.« less

Uniform circular motion concept attainment through circle share learning model using real media

NASA Astrophysics Data System (ADS)

Ponimin; Suparmi; Sarwanto; Sunarno, W.

2017-01-01

Uniform circular motion is an important concept and has many applications in life. Student’s concept understanding of uniform circular motion is not optimal because the teaching learning is not carried out properly in accordance with the characteristics of the concept. To improve student learning outcomes required better teaching learning which is match with the characteristics of uniform circular motion. The purpose of the study is to determine the effect of real media and circle share model to the understanding of the uniform circular motion concept. The real media was used to visualize of uniform circular motion concept. The real media consists of toy car, round table and spring balance. Circle share model is a learning model through discussion sequentially and programmed. Each group must evaluate the worksheets of another group in a circular position. The first group evaluates worksheets the second group, the second group evaluates worksheets third group, and the end group evaluates the worksheets of the first group. Assessment of learning outcomes includes experiment worksheets and post-test of students. Based on data analysis we obtained some findings. First, students can explain the understanding of uniform circular motion whose angular velocity and speed is constant correctly. Second, students can distinguish the angular velocity and linear velocity correctly. Third, students can explain the direction of the linear velocity vector and the direction of the centripetal force vector. Fourth, the student can explain the influence of the mass, radius, and velocity toward the centripetal force. Fifth, students can explain the principle of combined of wheels. Sixth, teaching learning used circle share, can increase student activity, experimental results and efficiency of discussion time.

Influence of circular stapler diameter on postoperative stenosis after laparoscopic gastrojejunal anastomosis in morbid obesity.

PubMed

Markar, Sheraz R; Penna, Marta; Venkat-Ramen, Vishal; Karthikesalingam, Alan; Hashemi, Majid

2012-01-01

The aim of the present study was to provide a pooled analysis of individual small trials comparing 21-mm and 25-mm circular stapled laparoscopic gastrojejunal (GJ) anastomosis in morbid obesity surgery. A systematic literature search of MEDLINE, Embase, and Cochrane library databases was performed to identify all relevant studies comparing 21-mm and 25-mm circular stapled laparoscopic GJ anastomosis in morbid obesity surgery. The primary outcomes were GJ stenosis and the interval to GJ stenosis. The secondary outcomes were the estimated weight loss, GJ diameter, and the number of endoscopic dilations. Pooled odds ratios were calculated for categorical outcomes and weighted mean differences for continuous outcomes. Five trials were included, comprising 1217 patients (393 with 21-mm and 824 with 25-mm circular GJ anastomoses). The primary outcome analysis revealed a significantly increased incidence of intraluminal stenosis associated with the 21-mm circular stapler (pooled odds ratio 3.54; P < .0001). The secondary outcome analysis revealed a significantly reduced GJ anastomotic diameter on endoscopy with the 21-mm circular stapler group (weighted mean difference -1.67; P = .002). Statistical analysis revealed no significant difference between the groups for the interval to stenosis, number of endoscopic dilations, and estimated weight loss. The results of the present pooled analysis have demonstrated a significantly increased incidence of symptomatic stenosis associated with the 21-mm circular stapler compared with the 25-mm stapler. This serves as evidence to validate the preferential selection of the 25-mm circular stapler for laparoscopic GJ bypass. Copyright © 2012 American Society for Metabolic and Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

Recent advancement in the field of two-dimensional correlation spectroscopy

NASA Astrophysics Data System (ADS)

Noda, Isao

2008-07-01

The recent advancement in the field of 2D correlation spectroscopy is reviewed with the emphasis on a number of papers published during the last two years. Topics covered by this comprehensive review include books, review articles, and noteworthy developments in the theory and applications of 2D correlation spectroscopy. New 2D correlation techniques are discussed, such as kernel analysis and augmented 2D correlation, model-based correlation, moving window analysis, global phase angle, covariance and correlation coefficient mapping, sample-sample correlation, hybrid and hetero correlation, pretreatment and transformation of data, and 2D correlation combined with other chemometrics techniques. Perturbation methods of both static (e.g., temperature, composition, pressure and stress, spatial distribution and orientation) and dynamic types (e.g., rheo-optical and acoustic, chemical reactions and kinetics, H/D exchange, sorption and diffusion) currently in use are examined. Analytical techniques most commonly employed in 2D correlation spectroscopy are IR, Raman, and NIR, but the growing use of other probes is also noted, including fluorescence, emission, Raman optical activity and vibrational circular dichroism, X-ray absorption and scattering, NMR, mass spectrometry, and even chromatography. The field of applications for 2D correlation spectroscopy is very diverse, encompassing synthetic polymers, liquid crystals, Langmuir-Blodgett films, proteins and peptides, natural polymers and biomaterials, pharmaceuticals, food and agricultural products, water, solutions, inorganic, organic, hybrid or composite materials, and many more.

Lagrangian Visualization and Real-Time Identification of the Vortex Shedding Time in the Wake of a Circular Cylinder

NASA Astrophysics Data System (ADS)

Rockwood, Matthew P.

The flow around a circular cylinder, a canonical bluff body, has been extensively studied in the literature to determine the mechanisms that cause the formation of vortices in the cylinder wake. Understanding of these mechanisms has led to myriad attempts to control the vortices either to mitigate the oscillating forces they cause, or to augment them in order to enhance mixing in the near-wake. While these flow control techniques have been effective at low Reynolds numbers, they generally lose effectiveness or require excessive power at Reynolds numbers commonly experienced in practical applications. For this reason, new methods for identifying the locations of vortices and their shedding time could increase the effectiveness of the control techniques. In the current work, two-dimensional, two-component velocity data was collected in the wake of a circular cylinder using a planar digital particle image velocimetry (DPIV) measurement system at Reynolds numbers of 9,000 and 19,000. This experimental data, as well as two-dimensional simulation data at a Reynolds number of 150, and three-dimensional simulation data at a Reynolds number of 400, is used to calculate the finite-time Lyapunov exponent (FTLE) field. The locations of Lagrangian saddles, identified as non-parallel intersections of positive and negative time FTLE ridges, are shown to indicate the timing of von Karman vortex shedding in the wake of a circular cylinder. The Lagrangian saddle found upstream of a forming and subsequently shedding vortex is shown to clearly accelerate away from the cylinder surface as the vortex begins to shed. This provides a novel, objective method to determine the timing of vortex shedding. The saddles are impossible to track in real-time, however, since future flow field data is needed for the computation of the FTLE fields. In order to detect the Lagrangian saddle acceleration without direct access to the FTLE, the saddle dynamics are connected to measurable surface quantities on a circular cylinder in crossflow. The acceleration of the Lagrangian saddle occurs simultaneously with a maximum in lift in both numerical cases, and with a minimum in the static pressure at a location slightly upstream of the mean separation location in the numerical cases, as well as the experimental data at a Reynolds number of 19,000. This allows the von Karman vortex shedding time, determined objectively by the acceleration of the Lagrangian saddle away from the circular cylinder, to be detected by a minimum in the static pressure at one location on the cylinder, a quantity that can be measured in real-time using available pressure sensors. These results can be used to place sensors in optimal locations on bluff bodies to inform closed-loop flow control algorithms of the timing of von Karman vortex shedding.

Microwave Ablation: Comparison of Simultaneous and Sequential Activation of Multiple Antennas in Liver Model Systems

PubMed Central

Harari, Colin M.; Magagna, Michelle; Bedoya, Mariajose; Lee, Fred T.; Lubner, Meghan G.; Hinshaw, J. Louis; Ziemlewicz, Timothy

2016-01-01

Purpose To compare microwave ablation zones created by using sequential or simultaneous power delivery in ex vivo and in vivo liver tissue. Materials and Methods All procedures were approved by the institutional animal care and use committee. Microwave ablations were performed in both ex vivo and in vivo liver models with a 2.45-GHz system capable of powering up to three antennas simultaneously. Two- and three-antenna arrays were evaluated in each model. Sequential and simultaneous ablations were created by delivering power (50 W ex vivo, 65 W in vivo) for 5 minutes per antenna (10 and 15 minutes total ablation time for sequential ablations, 5 minutes for simultaneous ablations). Thirty-two ablations were performed in ex vivo bovine livers (eight per group) and 28 in the livers of eight swine in vivo (seven per group). Ablation zone size and circularity metrics were determined from ablations excised postmortem. Mixed effects modeling was used to evaluate the influence of power delivery, number of antennas, and tissue type. Results On average, ablations created by using the simultaneous power delivery technique were larger than those with the sequential technique (P < .05). Simultaneous ablations were also more circular than sequential ablations (P = .0001). Larger and more circular ablations were achieved with three antennas compared with two antennas (P < .05). Ablations were generally smaller in vivo compared with ex vivo. Conclusion The use of multiple antennas and simultaneous power delivery creates larger, more confluent ablations with greater temperatures than those created with sequential power delivery. © RSNA, 2015 PMID:26133361

Real-time high-resolution measurement of collagen alignment in dynamically loaded soft tissue.

PubMed

York, Timothy; Kahan, Lindsey; Lake, Spencer P; Gruev, Viktor

2014-06-01

A technique for creating maps of the direction and strength of fiber alignment in collagenous soft tissues is presented. The method uses a division of focal plane polarimeter to measure circularly polarized light transmitted through the tissue. The architecture of the sensor allows measurement of the retardance and fiber alignment at the full frame rate of the sensor without any moving optics. The technique compares favorably to the standard method of using a rotating polarizer. How the new technique enables real-time capture of the full angular spread of fiber alignment and retardance under various cyclic loading conditions is illustrated.

Automatic screening and classification of diabetic retinopathy and maculopathy using fuzzy image processing.

PubMed

Rahim, Sarni Suhaila; Palade, Vasile; Shuttleworth, James; Jayne, Chrisina

2016-12-01

Digital retinal imaging is a challenging screening method for which effective, robust and cost-effective approaches are still to be developed. Regular screening for diabetic retinopathy and diabetic maculopathy diseases is necessary in order to identify the group at risk of visual impairment. This paper presents a novel automatic detection of diabetic retinopathy and maculopathy in eye fundus images by employing fuzzy image processing techniques. The paper first introduces the existing systems for diabetic retinopathy screening, with an emphasis on the maculopathy detection methods. The proposed medical decision support system consists of four parts, namely: image acquisition, image preprocessing including four retinal structures localisation, feature extraction and the classification of diabetic retinopathy and maculopathy. A combination of fuzzy image processing techniques, the Circular Hough Transform and several feature extraction methods are implemented in the proposed system. The paper also presents a novel technique for the macula region localisation in order to detect the maculopathy. In addition to the proposed detection system, the paper highlights a novel online dataset and it presents the dataset collection, the expert diagnosis process and the advantages of our online database compared to other public eye fundus image databases for diabetic retinopathy purposes.

A genetic scale of reading frame coding.

PubMed

Michel, Christian J

2014-08-21

The reading frame coding (RFC) of codes (sets) of trinucleotides is a genetic concept which has been largely ignored during the last 50 years. A first objective is the definition of a new and simple statistical parameter PrRFC for analysing the probability (efficiency) of reading frame coding (RFC) of any trinucleotide code. A second objective is to reveal different classes and subclasses of trinucleotide codes involved in reading frame coding: the circular codes of 20 trinucleotides and the bijective genetic codes of 20 trinucleotides coding the 20 amino acids. This approach allows us to propose a genetic scale of reading frame coding which ranges from 1/3 with the random codes (RFC probability identical in the three frames) to 1 with the comma-free circular codes (RFC probability maximal in the reading frame and null in the two shifted frames). This genetic scale shows, in particular, the reading frame coding probabilities of the 12,964,440 circular codes (PrRFC=83.2% in average), the 216 C(3) self-complementary circular codes (PrRFC=84.1% in average) including the code X identified in eukaryotic and prokaryotic genes (PrRFC=81.3%) and the 339,738,624 bijective genetic codes (PrRFC=61.5% in average) including the 52 codes without permuted trinucleotides (PrRFC=66.0% in average). Otherwise, the reading frame coding probabilities of each trinucleotide code coding an amino acid with the universal genetic code are also determined. The four amino acids Gly, Lys, Phe and Pro are coded by codes (not circular) with RFC probabilities equal to 2/3, 1/2, 1/2 and 2/3, respectively. The amino acid Leu is coded by a circular code (not comma-free) with a RFC probability equal to 18/19. The 15 other amino acids are coded by comma-free circular codes, i.e. with RFC probabilities equal to 1. The identification of coding properties in some classes of trinucleotide codes studied here may bring new insights in the origin and evolution of the genetic code. Copyright © 2014 Elsevier Ltd. All rights reserved.

Line plus arc source trajectories and their R-line coverage for long-object cone-beam imaging with a C-arm system

NASA Astrophysics Data System (ADS)

Yu, Zhicong; Wunderlich, Adam; Dennerlein, Frank; Lauritsch, Günter; Noo, Frédéric

2011-06-01

Cone-beam imaging with C-arm systems has become a valuable tool in interventional radiology. Currently, a simple circular trajectory is used, but future applications should use more sophisticated source trajectories, not only to avoid cone-beam artifacts but also to allow extended volume imaging. One attractive strategy to achieve these two goals is to use a source trajectory that consists of two parallel circular arcs connected by a line segment, possibly with repetition. In this work, we address the question of R-line coverage for such a trajectory. More specifically, we examine to what extent R-lines for such a trajectory cover a central cylindrical region of interest (ROI). An R-line is a line segment connecting any two points on the source trajectory. Knowledge of R-line coverage is crucial because a general theory for theoretically exact and stable image reconstruction from axially truncated data is only known for the points in the scanned object that lie on R-lines. Our analysis starts by examining the R-line coverage for the elemental trajectories consisting of (i) two parallel circular arcs and (ii) a circular arc connected orthogonally to a line segment. Next, we utilize our understanding of the R-lines for the aforementioned elemental trajectories to determine the R-line coverage for the trajectory consisting of two parallel circular arcs connected by a tightly fit line segment. For this trajectory, we find that the R-line coverage is insufficient to completely cover any central ROI. Because extension of the line segment beyond the circular arcs helps to increase the R-line coverage, we subsequently propose a trajectory composed of two parallel circular arcs connected by an extended line. We show that the R-lines for this trajectory can fully cover a central ROI if the line extension is long enough. Our presentation includes a formula for the minimum line extension needed to achieve full R-line coverage of an ROI with a specified size, and also includes a preliminary study on the required detector size, showing that the R-lines added by the line extension are not constraining.

Circular polarization in a non-magnetic resonant tunneling device.

PubMed

Dos Santos, Lara F; Gobato, Yara Galvão; Teodoro, Márcio D; Lopez-Richard, Victor; Marques, Gilmar E; Brasil, Maria Jsp; Orlita, Milan; Kunc, Jan; Maude, Duncan K; Henini, Mohamed; Airey, Robert J

2011-01-25

We have investigated the polarization-resolved photoluminescence (PL) in an asymmetric n-type GaAs/AlAs/GaAlAs resonant tunneling diode under magnetic field parallel to the tunnel current. The quantum well (QW) PL presents strong circular polarization (values up to -70% at 19 T). The optical emission from GaAs contact layers shows evidence of highly spin-polarized two-dimensional electron and hole gases which affects the spin polarization of carriers in the QW. However, the circular polarization degree in the QW also depends on various other parameters, including the g-factors of the different layers, the density of carriers along the structure, and the Zeeman and Rashba effects.

Circular polarization in a non-magnetic resonant tunneling device

PubMed Central

2011-01-01

We have investigated the polarization-resolved photoluminescence (PL) in an asymmetric n-type GaAs/AlAs/GaAlAs resonant tunneling diode under magnetic field parallel to the tunnel current. The quantum well (QW) PL presents strong circular polarization (values up to -70% at 19 T). The optical emission from GaAs contact layers shows evidence of highly spin-polarized two-dimensional electron and hole gases which affects the spin polarization of carriers in the QW. However, the circular polarization degree in the QW also depends on various other parameters, including the g-factors of the different layers, the density of carriers along the structure, and the Zeeman and Rashba effects. PMID:21711613

n-Nucleotide circular codes in graph theory.

PubMed

Fimmel, Elena; Michel, Christian J; Strüngmann, Lutz

2016-03-13

The circular code theory proposes that genes are constituted of two trinucleotide codes: the classical genetic code with 61 trinucleotides for coding the 20 amino acids (except the three stop codons {TAA,TAG,TGA}) and a circular code based on 20 trinucleotides for retrieving, maintaining and synchronizing the reading frame. It relies on two main results: the identification of a maximal C(3) self-complementary trinucleotide circular code X in genes of bacteria, eukaryotes, plasmids and viruses (Michel 2015 J. Theor. Biol. 380, 156-177. (doi:10.1016/j.jtbi.2015.04.009); Arquès & Michel 1996 J. Theor. Biol. 182, 45-58. (doi:10.1006/jtbi.1996.0142)) and the finding of X circular code motifs in tRNAs and rRNAs, in particular in the ribosome decoding centre (Michel 2012 Comput. Biol. Chem. 37, 24-37. (doi:10.1016/j.compbiolchem.2011.10.002); El Soufi & Michel 2014 Comput. Biol. Chem. 52, 9-17. (doi:10.1016/j.compbiolchem.2014.08.001)). The univerally conserved nucleotides A1492 and A1493 and the conserved nucleotide G530 are included in X circular code motifs. Recently, dinucleotide circular codes were also investigated (Michel & Pirillo 2013 ISRN Biomath. 2013, 538631. (doi:10.1155/2013/538631); Fimmel et al. 2015 J. Theor. Biol. 386, 159-165. (doi:10.1016/j.jtbi.2015.08.034)). As the genetic motifs of different lengths are ubiquitous in genes and genomes, we introduce a new approach based on graph theory to study in full generality n-nucleotide circular codes X, i.e. of length 2 (dinucleotide), 3 (trinucleotide), 4 (tetranucleotide), etc. Indeed, we prove that an n-nucleotide code X is circular if and only if the corresponding graph [Formula: see text] is acyclic. Moreover, the maximal length of a path in [Formula: see text] corresponds to the window of nucleotides in a sequence for detecting the correct reading frame. Finally, the graph theory of tournaments is applied to the study of dinucleotide circular codes. It has full equivalence between the combinatorics theory (Michel & Pirillo 2013 ISRN Biomath. 2013, 538631. (doi:10.1155/2013/538631)) and the group theory (Fimmel et al. 2015 J. Theor. Biol. 386, 159-165. (doi:10.1016/j.jtbi.2015.08.034)) of dinucleotide circular codes while its mathematical approach is simpler. © 2016 The Author(s).

Generation of capillary instabilities by external disturbances in a liquid jet. Ph.D. Thesis - State Univ. of N.Y.

NASA Technical Reports Server (NTRS)

Leib, S. J.

1985-01-01

The receptivity problem in a circular liquid jet is considered. A time harmonic axial pressure gradient is imposed on the steady, parallel flow of a jet of liquid emerging from a circular duct. Using a technique developed in plasma physics a casual solution to the forced problem is obtained over certain ranges of Weber number for a number of mean velocity profiles. This solution contains a term which grows exponentially in the downstream direction and can be identified with a capillary instability wave. Hence, it is found that the externally imposed disturbances can indeed trigger instability waves in a liquid jet. The amplitude of the instability wave generated relative to the amplitude of the forcing is computed numerically for a number of cases.

Study on the interaction between cinnamic acid and lysozyme

NASA Astrophysics Data System (ADS)

Zhang, Hong-Mei; Chen, Jian; Zhou, Qiu-Hua; Shi, Yue-Qin; Wang, Yan-Qing

2011-02-01

The interaction between lysozyme and cinnamic acid was investigated systematically by ultraviolet-vis absorbance, circular dichroism, fluorescence, synchronous fluorescence, and three-dimensional fluorescence spectra techniques at pH 7.40. The binding constants, quenching mechanism, and the number of binding sites were determined by the quenching of lysozyme fluorescence in presence of cinnamic acid. The results showed that the fluorescence quenching of lysozyme by cinnamic acid was a result of the formation of cinnamic acid-lysozyme complex. The hydrophobic and electrostatic interactions played major roles in stabilizing the complex; the distance r between donor and acceptor was obtained to be 2.07 nm according to Förster's theory; the effect of cinnamic acid on the conformation of lysozyme was analyzed using synchronous fluorescence, circular dichroism and three-dimensional fluorescence spectra.

Flexible particle manipulation techniques with conical refraction-based optical tweezers

NASA Astrophysics Data System (ADS)

McDougall, C.; Henderson, Robert; Carnegie, David J.; Sokolovskii, Grigorii S.; Rafailov, Edik U.; McGloin, David

2012-10-01

We present an optimized optical tweezers system based upon the conical refraction of circularly polarized light in a biaxial crystal. The described optical arrangement avoids distortions to the Lloyd plane rings that become apparent when working with circularly polarized light in conventional optical tweezers. We demonstrate that the intensity distribution of the conically diffracted light permits optical manipulation of high and low refractive index particles simultaneously. Such trapping is in three dimensions and not limited to the Lloyd plane rings. By removal of a quarter waveplate the system also permits the study of linearly polarized conical refraction. We show that particle position in the Raman plane is determined by beam power, and indicates that true optical tweezing is not taking place in this part of the beam.

76 FR 45657 - Airworthiness Directives; Cessna Aircraft Company (Cessna) Models 337, 337A (USAF 02B), 337B...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-01

... flight of civil aircraft in air commerce by prescribing regulations for practices, methods, and... incorporated before further flight if damage or signs of distress are found. (h) Alternative Methods of..., such as FAA Advisory Circular (AC) 43.13-1B Acceptable Methods, Techniques, and Practices--Aircraft...

Mechanical Circle-Squaring

ERIC Educational Resources Information Center

Wagon, Stan; Cox, Barry

2009-01-01

A technique discovered in 1939 can be used to build a device that is driven by standard circular motion (as in a drill press) and drills exact square holes. This device is quite different from the classic design by Watts, which uses a Reuleaux triangle and drills a hole that is almost, but not exactly, square. We describe the device in detail,…

Further Results in Bend-Buckling Analysis of Ring Stiffened Cylindrical Shells.

DTIC Science & Technology

1986-08-01

Submerged Shell Targets, NSWC TR 84-380, Dec 1984. 2. Moussouros, M., "Finite Element Modeling Techniques for Buckling Analysis of Cylindrical Shells...KCR, MBR , M0 , F0 , and I, R is the mean radius as given by R0 ) R0 - Mean radius of circular cylindrical shell (perfect shell or radius of

Improved Direct Methanol Fuel Cell Stack

DOEpatents

Wilson, Mahlon S.; Ramsey, John C.

2005-03-08

A stack of direct methanol fuel cells exhibiting a circular footprint. A cathode and anode manifold, tie-bolt penetrations and tie-bolts are located within the circular footprint. Each fuel cell uses two graphite-based plates. One plate includes a cathode active area that is defined by serpentine channels connecting the inlet and outlet cathode manifold. The other plate includes an anode active area defined by serpentine channels connecting the inlet and outlet of the anode manifold, where the serpentine channels of the anode are orthogonal to the serpentine channels of the cathode. Located between the two plates is the fuel cell active region.

Circular RNA hsa_circ_0016788 regulates hepatocellular carcinoma tumorigenesis through miR-486/CDK4 pathway.

PubMed

Guan, Zheng; Tan, Jing; Gao, Wei; Li, Xin; Yang, Yuandong; Li, Xiaogang; Li, Yingchao; Wang, Qiang

2018-06-19

Recent studies have revealed that circular RNAs (circRNAs) play important roles in the tumorigenesis of human cancer, including hepatocellular carcinoma (HCC). In present study, we screen the circular RNA expression profiles in HCC tissue and investigate the molecular roles on HCC tumorigenesis. Human circRNA microarray analysis showed there were total 1,245 differently expressed circular RNAs, including 756 up-regulated circRNAs and 489 down-regulated circRNAs, in three pairs of HCC tissue and adjacent normal tissue. Hsa_circ_0016788 was identified to be up-regulated in both HCC tissue and cell lines. Loss-of-functional experiments in vivo and vitro revealed that hsa_circ_0016788 silencing inhibited the proliferation, invasion and promoted the apoptosis in vitro, and inhibited the tumor growth in vivo. Bioinformatics tools and luciferase reporter assay validated that miR-486 targeted hsa_circ_0016788 and CDK4 accompanying with negatively correlated expression, suggesting the hsa_circ_0016788/miR-486/CDK4 pathway. Receiver operating characteristic (ROC) curve showed that hsa_circ_0016788 had high diagnostic value (AUC = 0.851). In summary, results reveal the role of hsa_circ_0016788/miR-486/CDK4 in HCC tumorigenesis, providing a novel therapeutic target for HCC. © 2018 Wiley Periodicals, Inc.

Simple graph models of information spread in finite populations

PubMed Central

Voorhees, Burton; Ryder, Bergerud

2015-01-01

We consider several classes of simple graphs as potential models for information diffusion in a structured population. These include biases cycles, dual circular flows, partial bipartite graphs and what we call ‘single-link’ graphs. In addition to fixation probabilities, we study structure parameters for these graphs, including eigenvalues of the Laplacian, conductances, communicability and expected hitting times. In several cases, values of these parameters are related, most strongly so for partial bipartite graphs. A measure of directional bias in cycles and circular flows arises from the non-zero eigenvalues of the antisymmetric part of the Laplacian and another measure is found for cycles as the value of the transition probability for which hitting times going in either direction of the cycle are equal. A generalization of circular flow graphs is used to illustrate the possibility of tuning edge weights to match pre-specified values for graph parameters; in particular, we show that generalizations of circular flows can be tuned to have fixation probabilities equal to the Moran probability for a complete graph by tuning vertex temperature profiles. Finally, single-link graphs are introduced as an example of a graph involving a bottleneck in the connection between two components and these are compared to the partial bipartite graphs. PMID:26064661

Ferrofluid lubrication of circular squeeze film bearings controlled by variable magnetic field with rotations of the discs, porosity and slip velocity

NASA Astrophysics Data System (ADS)

Shah, Rajesh C.; Shah, Rajiv B.

2017-12-01

Based on the Shliomis ferrofluid flow model (SFFM) and continuity equation for the film as well as porous region, modified Reynolds equation for lubrication of circular squeeze film bearings is derived by considering the effects of oblique radially variable magnetic field (VMF), slip velocity at the film-porous interface and rotations of both the discs. The squeeze film bearings are made up of circular porous upper disc of different shapes (exponential, secant, mirror image of secant and parallel) and circular impermeable flat lower disc. The validity of Darcy's Law is assumed in the porous region. The SFFM is important because it includes the effects of rotations of the carrier liquid as well as magnetic particles. The VMF is used because of its advantage of generating maximum field at the required active contact area of the bearing design system. Also, the effect of porosity is included because of its advantageous property of self-lubrication. Using Reynolds equation, general form of pressure equation is derived and expression for dimensionless load-carrying capacity is obtained. Using this expression, results for different bearing design systems (due to different shapes of the upper disc) are computed and compared for variation of different parameters.

Microwave birefringent metamaterials for polarization conversion based on spoof surface plasmon polariton modes

PubMed Central

Li, Yongfeng; Zhang, Jieqiu; Ma, Hua; Wang, Jiafu; Pang, Yongqiang; Feng, Dayi; Xu, Zhuo; Qu, Shaobo

2016-01-01

We propose the design of wideband birefringent metamaterials based on spoof surface plasmon polaritons (SSPPs). Spatial k-dispersion design of SSPP modes in metamaterials is adopted to achieve high-efficiency transmission of electromagnetic waves through the metamaterial layer. By anisotropic design, the transmission phase accumulation in metamaterials can be independently modulated for x- and y-polarized components of incident waves. Since the dispersion curve of SSPPs is nonlinear, frequency-dependent phase differences can be obtained between the two orthogonal components of transmitted waves. As an example, we demonstrate a microwave birefringent metamaterials composed of fishbone structures. The full-polarization-state conversions on the zero-longitude line of Poincaré sphere can be fulfilled twice in 6–20 GHz for both linearly polarized (LP) and circularly polarized (CP) waves incidence. Besides, at a given frequency, the full-polarization-state conversion can be achieved by changing the polarization angle of the incident LP waves. Both the simulation and experiment results verify the high-efficiency polarization conversion functions of the birefringent metamaterial, including circular-to-circular, circular-to-linear(linear-to-circular), linear-to-linear polarization conversions. PMID:27698443

High-throughput sequencing reveals circular substrates for an archaeal RNA ligase

PubMed Central

Becker, Hubert F.; Héliou, Alice; Djaout, Kamel; Lestini, Roxane; Regnier, Mireille; Myllykallio, Hannu

2017-01-01

ABSTRACT It is only recently that the abundant presence of circular RNAs (circRNAs) in all kingdoms of Life, including the hyperthermophilic archaeon Pyrococcus abyssi, has emerged. This led us to investigate the physiologic significance of a previously observed weak intramolecular ligation activity of Pab1020 RNA ligase. Here we demonstrate that this enzyme, despite sharing significant sequence similarity with DNA ligases, is indeed an RNA-specific polynucleotide ligase efficiently acting on physiologically significant substrates. Using a combination of RNA immunoprecipitation assays and RNA-seq, our genome-wide studies revealed 133 individual circRNA loci in P. abyssi. The large majority of these loci interacted with Pab1020 in cells and circularization of selected C/D Box and 5S rRNA transcripts was confirmed biochemically. Altogether these studies revealed that Pab1020 is required for RNA circularization. Our results further suggest the functional speciation of an ancestral NTase domain and/or DNA ligase toward RNA ligase activity and prompt for further characterization of the widespread functions of circular RNAs in prokaryotes. Detailed insight into the cellular substrates of Pab1020 may facilitate the development of new biotechnological applications e.g. in ligation of preadenylated adaptors to RNA molecules. PMID:28277897

Development of image processing techniques for applications in flow visualization and analysis

NASA Technical Reports Server (NTRS)

Disimile, Peter J.; Shoe, Bridget; Toy, Norman; Savory, Eric; Tahouri, Bahman

1991-01-01

A comparison between two flow visualization studies of an axi-symmetric circular jet issuing into still fluid, using two different experimental techniques, is described. In the first case laser induced fluorescence is used to visualize the flow structure, whilst smoke is utilized in the second. Quantitative information was obtained from these visualized flow regimes using two different digital imaging systems. Results are presented of the rate at which the jet expands in the downstream direction and these compare favorably with the more established data.

A technique to measure rotordynamic coefficients in hydrostatic bearings

NASA Technical Reports Server (NTRS)

Capaldi, Russell J.

1993-01-01

An experimental technique is described for measuring the rotordynamic coefficients of fluid film journal bearings. The bearing tester incorporates a double-spool shaft assembly that permits independent control over the journal spin speed and the frequency of an adjustable-magnitude circular orbit. This configuration yields data that enables determination of the full linear anisotropic rotordynamic coefficient matrices. The dynamic force measurements were made simultaneously with two independent systems, one with piezoelectric load cells and the other with strain gage load cells. Some results are presented for a four-recess, oil-fed hydrostatic journal bearing.

The measurement of boundary layers on a compressor blade in cascade at high positive incidence angle. 2: Data report

NASA Technical Reports Server (NTRS)

Deutsch, S.; Zierke, W. C.

1986-01-01

Boundary layer and near-wake velocity measurements have been made in the well documented flow field about a double circular arc compressor blade in cascade, at an incidence angle of 5 deg. and a chord Reynolds number of 500,000. In Part 2 of this report these measurements were analyzed and presented in standard graphical format. The flow geometry, measurement techniques, and physics of the flow field were also discussed. In this, part 2 of the report, raw and analyzed data are presented in tabulated form in an attempt to make this data more accessible to computational comparison. Also included in part 2 is a description of the data analysis employed. A computer tape containing the data is available.

Cytotoxic steroids from the leaves of Dysoxylum binectariferum.

PubMed

Yan, Hui-Jiao; Wang, Jun-Song; Kong, Ling-Yi

2014-08-01

Four new cholestane-type (1-4) and two new ergostane-type (5, 6) steroids were isolated from the leaves of Dysoxylum binectariferum. Their structures were elucidated on the basis of spectroscopic analysis, including 1D and 2D NMR techniques. The absolute configurations were established by comparison with the literature and Mo2(OAc)4-induced electronic circular dichroism (ECD) data. All the isolates were evaluated for cytotoxicity against A549 (lung carcinoma), MCF-7 (breast adenocarcinoma), and HepG2 (hepatocellular carcinoma) human cancer cell lines. Three of the new cholestane-type steroids displayed potent antiproliferative effects on the tumor cells with IC50 values ranging from 1.5 to 9.6μM, whereas the two new ergostane-type (5, 6) steroids were deemed inactive. Copyright © 2014 Elsevier Inc. All rights reserved.

The effects of biological buffers TRIS, TAPS, TES on the stability of lysozyme.

PubMed

Pannuru, Pavani; Rani, Anjeeta; Venkatesu, Pannuru; Lee, Ming-Jer

2018-06-01

To explore the mechanism of lysozyme stabilization in buffer system, we have investigated the interactions between lysozyme and the biological buffers (TRIS, TAPS, and TES) using spectroscopic techniques, including ultraviolet-visible (UV-Vis), fluorescence, thermal fluorescence, dynamic light scattering (DLS), Fourier transform infrared spectroscopy (FTIR) and circular dichroism (CD) spectroscopy. From the series of spectroscopic studies, it is found that the native structure of the protein remains intact in the different concentrations (0.05, 0.1, 0.25, 0.5, and 1.0M) of the biological buffer aqueous solutions at pH7.0. Moreover, all these three investigated buffers are able to protect lysozyme against thermal denaturation, particularly in high concentration (1.0M) of the buffer aqueous solutions. Copyright © 2018 Elsevier B.V. All rights reserved.

Stiffness of frictional contact of dissimilar elastic solids

DOE PAGES

Lee, Jin Haeng; Gao, Yanfei; Bower, Allan F.; ...

2017-12-22

The classic Sneddon relationship between the normal contact stiffness and the contact size is valid for axisymmetric, frictionless contact, in which the two contacting solids are approximated by elastic half-spaces. Deviation from this result critically affects the accuracy of the load and displacement sensing nanoindentation techniques. This study gives a thorough numerical and analytical investigation of corrections needed to the Sneddon solution when finite Coulomb friction exists between an elastic half-space and a flat-ended rigid punch with circular or noncircular shape. Because of linearity of the Coulomb friction, the correction factor is found to be a function of the frictionmore » coefficient, Poisson's ratio, and the contact shape, but independent of the contact size. Two issues are of primary concern in the finite element simulations – adequacy of the mesh near the contact edge and the friction implementation methodology. Although the stick or slip zone sizes are quite different from the penalty or Lagrangian methods, the calculated contact stiffnesses are almost the same and may be considerably larger than those in Sneddon's solution. For circular punch contact, the numerical solutions agree remarkably well with a previous analytical solution. For non-circular punch contact, the results can be represented using the equivalence between the contact problem and bi-material fracture mechanics. Finally, the correction factor is found to be a product of that for the circular contact and a multiplicative factor that depends only on the shape of the punch but not on the friction coefficient or Poisson's ratio.« less

Detecting primordial gravitational waves with circular polarization of the redshifted 21 cm line. II. Forecasts

NASA Astrophysics Data System (ADS)

Mishra, Abhilash; Hirata, Christopher M.

2018-05-01

In the first paper of this series, we showed that the CMB quadrupole at high redshifts results in a small circular polarization of the emitted 21 cm radiation. In this paper we forecast the sensitivity of future radio experiments to measure the CMB quadrupole during the era of first cosmic light (z ˜20 ). The tomographic measurement of 21 cm circular polarization allows us to construct a 3D remote quadrupole field. Measuring the B -mode component of this remote quadrupole field can be used to put bounds on the tensor-to-scalar ratio r . We make Fisher forecasts for a future Fast Fourier Transform Telescope (FFTT), consisting of an array of dipole antennas in a compact grid configuration, as a function of array size and observation time. We find that a FFTT with a side length of 100 km can achieve σ (r )˜4 ×10-3 after ten years of observation and with a sky coverage fsky˜0.7 . The forecasts are dependent on the evolution of the Lyman-α flux in the pre-reionization era, that remains observationally unconstrained. Finally, we calculate the typical order of magnitudes for circular polarization foregrounds and comment on their mitigation strategies. We conclude that detection of primordial gravitational waves with 21 cm observations is in principle possible, so long as the primordial magnetic field amplitude is small, but would require a very futuristic experiment with corresponding advances in calibration and foreground suppression techniques.

Stiffness of frictional contact of dissimilar elastic solids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Jin Haeng; Gao, Yanfei; Bower, Allan F.

The classic Sneddon relationship between the normal contact stiffness and the contact size is valid for axisymmetric, frictionless contact, in which the two contacting solids are approximated by elastic half-spaces. Deviation from this result critically affects the accuracy of the load and displacement sensing nanoindentation techniques. This study gives a thorough numerical and analytical investigation of corrections needed to the Sneddon solution when finite Coulomb friction exists between an elastic half-space and a flat-ended rigid punch with circular or noncircular shape. Because of linearity of the Coulomb friction, the correction factor is found to be a function of the frictionmore » coefficient, Poisson's ratio, and the contact shape, but independent of the contact size. Two issues are of primary concern in the finite element simulations – adequacy of the mesh near the contact edge and the friction implementation methodology. Although the stick or slip zone sizes are quite different from the penalty or Lagrangian methods, the calculated contact stiffnesses are almost the same and may be considerably larger than those in Sneddon's solution. For circular punch contact, the numerical solutions agree remarkably well with a previous analytical solution. For non-circular punch contact, the results can be represented using the equivalence between the contact problem and bi-material fracture mechanics. Finally, the correction factor is found to be a product of that for the circular contact and a multiplicative factor that depends only on the shape of the punch but not on the friction coefficient or Poisson's ratio.« less

Stiffness of frictional contact of dissimilar elastic solids

NASA Astrophysics Data System (ADS)

Lee, Jin Haeng; Gao, Yanfei; Bower, Allan F.; Xu, Haitao; Pharr, George M.

2018-03-01

The classic Sneddon relationship between the normal contact stiffness and the contact size is valid for axisymmetric, frictionless contact, in which the two contacting solids are approximated by elastic half-spaces. Deviation from this result critically affects the accuracy of the load and displacement sensing nanoindentation techniques. This paper gives a thorough numerical and analytical investigation of corrections needed to the Sneddon solution when finite Coulomb friction exists between an elastic half-space and a flat-ended rigid punch with circular or noncircular shape. Because of linearity of the Coulomb friction, the correction factor is found to be a function of the friction coefficient, Poisson's ratio, and the contact shape, but independent of the contact size. Two issues are of primary concern in the finite element simulations - adequacy of the mesh near the contact edge and the friction implementation methodology. Although the stick or slip zone sizes are quite different from the penalty or Lagrangian methods, the calculated contact stiffnesses are almost the same and may be considerably larger than those in Sneddon's solution. For circular punch contact, the numerical solutions agree remarkably well with a previous analytical solution. For non-circular punch contact, the results can be represented using the equivalence between the contact problem and bi-material fracture mechanics. The correction factor is found to be a product of that for the circular contact and a multiplicative factor that depends only on the shape of the punch but not on the friction coefficient or Poisson's ratio.

Comparison of manual and mechanical cervical esophagogastric anastomosis after esophageal resection for squamous cell carcinoma: a prospective randomized controlled trial.

PubMed

Hsu, Hsao-Hsun; Chen, Jin-Shing; Huang, Pei-Ming; Lee, Jang-Ming; Lee, Yung-Chie

2004-06-01

The use of a circular stapler in cervical esophagogastric anastomosis remains controversial. This study was to compare the postoperative and long-term results of manual and mechanical techniques for cervical esophagogastric anastomosis after resection for squamous cell carcinoma. A prospective randomized controlled trial was undertaken in 63 patients with curatively resectable squamous cell cancer of the thoracic esophagus between 1996 and 1999. Patients were randomized to receive either a hand-sewn (32 patients) or circular stapled (31 patients) cervical esophagogastric anastomosis. The mean operating time was longer when the hand-sewn method was used (524 vs. 447 min, P < 0.001). Anastomotic leakage was noted in seven patients (22%) in the hand-sewn group and eight patients (26%) in the stapler group (P = NS). Hospital mortality occurred in four patients (13%) of the hand-sewn group and in three patients (10%) of the stapler group (P = NS). After the operation, four patients (14%) in the hand-sewn group and five patients (18%) in the stapler group developed a benign esophageal stricture (P = NS). The mean follow-up time was 24 months, and the rates of freedom from benign stricture and survival were comparable in each group. Performing cervical esophagogastric anastomoses using a circular mechanical stapler had a shorter operating time and a comparable outcome to the hand-sewn method. The circular mechanical stapler could be used as an alternative for cervical esophagogastric anastomosis after resection for esophageal squamous cell cancer.

Determination of the absolute configurations of natural products via density functional theory calculations of optical rotation, electronic circular dichroism, and vibrational circular dichroism: the cytotoxic sesquiterpene natural products quadrone, suberosenone, suberosanone, and suberosenol A acetate.

PubMed

Stephens, P J; McCann, D M; Devlin, F J; Smith, A B

2006-07-01

The determination of the absolute configurations (ACs) of chiral molecules using the chiroptical techniques of optical rotation (OR), electronic circular dichroism (ECD), and vibrational circular dichroism (VCD) has been revolutionized by the development of density functional theory (DFT) methods for the prediction of these properties. Here, we demonstrate the significance of these advances for the stereochemical characterization of natural products. Time-dependent DFT (TDDFT) calculations of the specific rotations, [alpha](D), of four cytotoxic natural products, quadrone (1), suberosenone (2), suberosanone (3), and suberosenol A acetate (4), are used to assign their ACs. TDDFT calculations of the ECD of 1 are used to assign its AC. The VCD spectrum of 1 is reported and also used, together with DFT calculations, to assign its AC. The ACs of 1 derived from its [alpha](D), ECD, and VCD are identical and in agreement with the AC previously determined via total synthesis. The previously undetermined ACs of 2-4, derived from their [alpha](D) values, have absolute configurations of their tricyclic cores identical to that of 1. Further studies of the ACs of these molecules using ECD and, especially, VCD are recommended to establish more definitively this finding. Our studies of the OR, ECD, and VCD of quadrone are the first to utilize DFT calculations of all three properties for the determination of the AC of a chiral natural product molecule.

A novel buoyancy technique optimizes simulated microgravity conditions for whole sensory organ culture in rotating bioreactors.

PubMed

Arnold, Heinz J P; Müller, Marcus; Waldhaus, Jörg; Hahn, Hartmut; Löwenheim, Hubert

2010-02-01

Whole-organ culture of a sensory organ in a rotating wall vessel bioreactor provides a powerful in vitro model for physiological and pathophysiological investigation as previously demonstrated for the postnatal inner ear. The model is of specific relevance as a tool for regeneration research. In the immature inner ear explant, the density was only 1.29 g/cm(3). The high density of 1.68 g/cm(3) of the functionally mature organ resulted in enhanced settling velocity and deviation from its ideal circular orbital path causing enhanced shear stress. The morphometric and physical properties, as well as the dynamic motion patterns of explants, were analyzed and numerically evaluated by an orbital path index. Application of a novel buoyancy bead technique resulted in a 6.5- to 14.8-fold reduction of the settling velocity. The deviation of the explant from its ideal circular orbital path was adjusted as indicated by an optimum value for the orbital path index (-1.0). Shear stress exerted on the inner ear explant was consequently reduced 6.4- to 15.0-fold. The culture conditions for postnatal stages were optimized, and the preconditions for transferring this in vitro model toward mature high-density stages established. This buoyancy technique may also be useful in tissue engineering of other high-density structures.

Evaluation of effectiveness of cement removal from implant-retained crowns using a proposed circular crisscross flossing technique.

PubMed

Ferreira, Cimara Fortes; Shafter, Mohamed Amer; Jain, Vinay; Wicks, Russel Anthony; Linder, Erno; Ledo, Carlos Alberto da Silva

2018-02-13

Extruded cement during dental implant crown cementation may cause peri-implant diseases if not removed adequately. Evaluate the efficiency of removal of cement after cementation of implant crowns using an experimental "circular crisscross flossing technique (CCCFT) flossing technique, compared to the conventional "C" shape flossing technique (CSFT). Twenty-four patients rendered 29 experimental and 29 control crowns. Prefabricated abutments were secured to the implant with the margins at least 1 mm subgingivally. The abutments were scanned using CADCAM technology and Emax crowns were fabricated in duplicates. Each crown was cemented separately and excess cement was removed using the CSFT and the CCFT techniques. After completion of cementation was completed, the screw access holes were accessed and the crown was unscrewed along with the abutment. The samples were disinfected using 70% ethanol for 10 minutes. Crowns were divided into 4 parts using a marker in order to facilitate measurement data collection. Vertical and horizontal measurements were made for extruded cement for each control and experimental groups by means of a digital microscope. One-hundred and seventeen measurements were made for each group. Mann-Whitney test was applied to verify statistical significance between the groups. The CCFT showed a highly statistically significant result (104.8 ± 13.66, p<0.0001) for cement removal compared with the CSFT (291.8 ± 21.96, p<0.0001). The vertical lengths of the extruded cement showed a median of 231.1 µm (IQR = 112.79 -398.39) and 43.62 µm (IQR = 0 - 180.21) for the control and the experimental flossing techniques, respectively. The horizontal length of the extruded cement showed a median of 987.1 µm (IQR = 476.7 - 1,933.58) and 139.2 µm (IQR = 0 - 858.28) for the control and the experimental flossing techniques, respectively. The CCFT showed highly statistically significant less cement after implant crowns cementation when compared with the CSFT.

Application of conformal transformation to elliptic geometry for electric impedance tomography.

PubMed

Yilmaz, Atila; Akdoğan, Kurtuluş E; Saka, Birsen

2008-03-01

Electrical impedance tomography (EIT) is a medical imaging modality that is used to compute the conductivity distribution through measurements on the cross-section of a body part. An elliptic geometry model, which defines a more general frame, ensures more accurate results in reconstruction and assessment of inhomogeneities inside. This study provides a link between the analytical solutions defined in circular and elliptical geometries on the basis of the computation of conformal mapping. The results defined as voltage distributions for the homogeneous case in elliptic and circular geometries have been compared with those obtained by the use of conformal transformation between elliptical and well-known circular geometry. The study also includes the results of the finite element method (FEM) as another approach for more complex geometries for the comparison of performance in other complex scenarios for eccentric inhomogeneities. The study emphasizes that for the elliptic case the analytical solution with conformal transformation is a reliable and useful tool for developing insight into more complex forms including eccentric inhomogeneities.

Polarised Photon Beams for the BGO-OD Experiment at ELSA

NASA Astrophysics Data System (ADS)

Zimmermann, T.; Bella, A.; Alef, S.; Bayadilov, D.; Beck, R.; Becker, M.; Bielefeldt, P.; Boese, S.; Braghieri, A.; Brinkmann, K.; Cole, P.; Curciarello, F.; De Leo, V.; Di Salvo, R.; Dutz, H.; Elsner, D.; Fantini, A.; Freyermuth, O.; Friedrich, S.; Frommberger, F.; Ganenko, V.; Gervino, G.; Ghio, F.; Giardina, G.; Goertz, S.; Gridnev, A.; Gutz, E.; Hammann, D.; Hannappel, J.; Hartmann, P.; Hillert, W.; Ignatov, A.; Jahn, R.; Joosten, R.; Jude, T. C.; Klein, F.; Koop, K.; Krusche, B.; Lapik, A.; Levi Sandri, P.; Lopatin, I. V.; Mandaglio, G.; Messi, F.; Messi, R.; Metag, V.; Moricciani, D.; Mushkarenkov, A.; Nanova, M.; Nedorezov, V.; Novinskiy, D.; Pedroni, P.; Reitz, B.; Romaniuk, M.; Rostomyan, T.; Rudnev, N.; Schaerf, C.; Scheluchin, G.; Schmieden, H.; Stugelev, A.; Sumachev, V.; Tarakanov, V.; Vegna, V.; Walther, D.; Watts, D.; Zaunick, H.

The new BGO-OD experiment at the electron accelerator ELSA, of the University of Bonn, is designed to study the reaction dynamics of nucleon excitations in meson photoproduction. It consists of a central BGO calorimeter with a magnetic spectrometer in forward direction. The physics programme includes the measurement of polarisation observables using linearly and circularly polarised photon beams. Linear polarisation is obtained by coherent bremsstrahlung off a diamond crystal, and circular polarisation is obtained via bremsstrahlung from longitudinally polarised electrons. The degree of linear polarisation is determined from the bremsstrahlung spectrum itself. To determine the polarisation of the circularly polarised photon beam, the polarisation of the electron beam is measured by a Møller polarimeter. As a preliminary consistency check, the (linear) polarisation observable, Σ, was compared to world data for π0 and η photoproduction. To determine the degree of circular polarisation, a Møller polarimeter was setup and first measurements of the electron beam polarisation performed.

Mechanism for circularization of linear DNAs: circular parvovirus MVM DNA is formed by a "noose" sliding in a "lasso"-like DNA structure.

PubMed

Bratosin, S; Laub, O; Tal, J; Aloni, Y

1979-09-01

During an electron-microscopic survey with the aim of identifying the parvovirus MVM transcription template, we observed previously unidentified structures of MVM DNA in lysates of virus-infected cells. These included double-stranded "lasso"-like structures and relaxed circles. Both structures were of unit length MVM DNA, indicating that they were not intermediates formed during replication; they each represented about 5% of the total nuclear MVM DNA. The proportion of these structures was unchanged after digestion with sodium dodecyl sulfate/Pronase and RNase and after mild denaturation treatment. Cleavage of the "lasso" structures with EcoRI restriction endonuclease indicated that the "noose" part of the "lasso" structure is located on the 5' side of the genomic single-stranded MVM DNA. A model is presented for the molecular nature of the circularization process of MVM DNA in which the "lasso" structures are identified as intermediates during circle formation. This model proposes a mechanism for circularization of linear DNAs.

An interdisciplinary analysis of multispectral satellite data for selected cover types in the Colorado mountains, using automatic data processing techniques

NASA Technical Reports Server (NTRS)

Hoffer, R. M. (Principal Investigator)

1974-01-01

The author has identified the following significant results. In the San Juan Mountains there exists a group of structural and topographic features which suggest a common origin. The relative positions of the San Juan Depression with the Silverton and Lake City Calderas indicate they are possibly on the edge of a large circular feature. Comparison with the 1:250,000 scale Durango Geologic Map reveals a series of radial and arcuate faults concentric with the major circular feature. Such a fracture pattern implies that the circular feature may represent the extent of a major domal uplift in the area. The uplift was very likely due to the sub-crustal emplacement of the parent magma of the San Juan volcanics and intrusives. The broad doming led to the formation of a zone of tensional ring fractures which acted as conduits of release for the magma and the eventual development of the various calderas. The ring fracturing was probably incomplete with hinging occurring in the southern and southwestern portions of the dome accounting for the lack of development of caldera structures in that portion of the area.

Acoustic imaging of a duct spinning mode by the use of an in-duct circular microphone array.

PubMed

Wei, Qingkai; Huang, Xun; Peers, Edward

2013-06-01

An imaging method of acoustic spinning modes propagating within a circular duct simply with surface pressure information is introduced in this paper. The proposed method is developed in a theoretical way and is demonstrated by a numerical simulation case. Nowadays, the measurements within a duct have to be conducted using in-duct microphone array, which is unable to provide information of complete acoustic solutions across the test section. The proposed method can estimate immeasurable information by forming a so-called observer. The fundamental idea behind the testing method was originally developed in control theory for ordinary differential equations. Spinning mode propagation, however, is formulated in partial differential equations. A finite difference technique is used to reduce the associated partial differential equations to a classical form in control. The observer method can thereafter be applied straightforwardly. The algorithm is recursive and, thus, could be operated in real-time. A numerical simulation for a straight circular duct is conducted. The acoustic solutions on the test section can be reconstructed with good agreement to analytical solutions. The results suggest the potential and applications of the proposed method.

Extinction efficiencies from DDA calculations solved for finite circular cylinders and disks

NASA Technical Reports Server (NTRS)

Withrow, J. R.; Cox, S. K.

1993-01-01

One of the most commonly noted uncertainties with respect to the modeling of cirrus clouds and their effect upon the planetary radiation balance is the disputed validity of the use of Mie scattering results as an approximation to the scattering results of the hexagonal plates and columns found in cirrus clouds. This approximation has historically been a kind of default, a result of the lack of an appropriate analytical solution of Maxwell's equations to particles other than infinite cylinders and spheroids. Recently, however, the use of such approximate techniques as the Discrete Dipole Approximation has made scattering solutions on such particles a computationally intensive but feasible possibility. In this study, the Discrete Dipole Approximation (DDA) developed by Flatau (1992) is used to find such solutions for homogeneous, circular cylinders and disks. This can serve to not only assess the validity of the current radiative transfer schemes which are available for the study of cirrus but also to extend the current approximation of equivalent spheres to an approximation of second order, homogeneous finite circular cylinders and disks. The results will be presented in the form of a single variable, the extinction efficiency.

Design of efficient circularly symmetric two-dimensional variable digital FIR filters.

PubMed

Bindima, Thayyil; Elias, Elizabeth

2016-05-01

Circularly symmetric two-dimensional (2D) finite impulse response (FIR) filters find extensive use in image and medical applications, especially for isotropic filtering. Moreover, the design and implementation of 2D digital filters with variable fractional delay and variable magnitude responses without redesigning the filter has become a crucial topic of interest due to its significance in low-cost applications. Recently the design using fixed word length coefficients has gained importance due to the replacement of multipliers by shifters and adders, which reduces the hardware complexity. Among the various approaches to 2D design, transforming a one-dimensional (1D) filter to 2D by transformation, is reported to be an efficient technique. In this paper, 1D variable digital filters (VDFs) with tunable cut-off frequencies are designed using Farrow structure based interpolation approach, and the sub-filter coefficients in the Farrow structure are made multiplier-less using canonic signed digit (CSD) representation. The resulting performance degradation in the filters is overcome by using artificial bee colony (ABC) optimization. Finally, the optimized 1D VDFs are mapped to 2D using generalized McClellan transformation resulting in low complexity, circularly symmetric 2D VDFs with real-time tunability.

Design of efficient circularly symmetric two-dimensional variable digital FIR filters

PubMed Central

Bindima, Thayyil; Elias, Elizabeth

2016-01-01

Circularly symmetric two-dimensional (2D) finite impulse response (FIR) filters find extensive use in image and medical applications, especially for isotropic filtering. Moreover, the design and implementation of 2D digital filters with variable fractional delay and variable magnitude responses without redesigning the filter has become a crucial topic of interest due to its significance in low-cost applications. Recently the design using fixed word length coefficients has gained importance due to the replacement of multipliers by shifters and adders, which reduces the hardware complexity. Among the various approaches to 2D design, transforming a one-dimensional (1D) filter to 2D by transformation, is reported to be an efficient technique. In this paper, 1D variable digital filters (VDFs) with tunable cut-off frequencies are designed using Farrow structure based interpolation approach, and the sub-filter coefficients in the Farrow structure are made multiplier-less using canonic signed digit (CSD) representation. The resulting performance degradation in the filters is overcome by using artificial bee colony (ABC) optimization. Finally, the optimized 1D VDFs are mapped to 2D using generalized McClellan transformation resulting in low complexity, circularly symmetric 2D VDFs with real-time tunability. PMID:27222739

New insights in morphological analysis for managing activated sludge systems.

PubMed

Oliveira, Pedro; Alliet, Marion; Coufort-Saudejaud, Carole; Frances, Christine

2018-06-01

In activated sludge (AS) process, the impact of the operational parameters on process efficiency is assumed to be correlated with the sludge properties. This study provides a better insight into these interactions by subjecting a laboratory-scale AS system to a sequence of operating condition modifications enabling typical situations of a wastewater treatment plant to be represented. Process performance was assessed and AS floc morphology (size, circularity, convexity, solidity and aspect ratio) was quantified by measuring 100,000 flocs per sample with an automated image analysis technique. Introducing 3D distributions, which combine morphological properties, allowed the identification of a filamentous bulking characterized by a floc population shift towards larger sizes and lower solidity and circularity values. Moreover, a washout phenomenon was characterized by smaller AS flocs and an increase in their solidity. Recycle ratio increase and COD:N ratio decrease both promoted a slight reduction of floc sizes and a constant evolution of circularity and convexity values. The analysis of the volume-based 3D distributions turned out to be a smart tool to combine size and shape data, allowing a deeper understanding of the dynamics of floc structure under process disturbances.

Analysis and Optimization of Four-Coil Planar Magnetically Coupled Printed Spiral Resonators.

PubMed

Khan, Sadeque Reza; Choi, GoangSeog

2016-08-03

High-efficiency power transfer at a long distance can be efficiently established using resonance-based wireless techniques. In contrast to the conventional two-coil-based inductive links, this paper presents a magnetically coupled fully planar four-coil printed spiral resonator-based wireless power-transfer system that compensates the adverse effect of low coupling and improves efficiency by using high quality-factor coils. A conformal architecture is adopted to reduce the transmitter and receiver sizes. Both square architecture and circular architectures are analyzed and optimized to provide maximum efficiency at a certain operating distance. Furthermore, their performance is compared on the basis of the power-transfer efficiency and power delivered to the load. Square resonators can produce higher measured power-transfer efficiency (79.8%) than circular resonators (78.43%) when the distance between the transmitter and receiver coils is 10 mm of air medium at a resonant frequency of 13.56 MHz. On the other hand, circular coils can deliver higher power (443.5 mW) to the load than the square coils (396 mW) under the same medium properties. The performance of the proposed structures is investigated by simulation using a three-layer human-tissue medium and by experimentation.

Aerodynamic Analysis of Body-Strake Configurations

DTIC Science & Technology

2006-06-01

combination by Macha . Adjustment for finite body was done based on the empirical correlation for circular bodies by Jorgensen. Additional adjustment...these cases were based on the results obtained with plain cylinders. Schematic from Macha . Fig. 2 also compares Macha’s results for circular...is apparent that Macha included in his charts plain cylinder data at s/r=1.0 and that his curves consider these data. In Section 5.5 of Ref. 6 he

The acoustic power of a vibrating clamped circular plate revisited in the wide low frequency range using expansion into the radial polynomials.

PubMed

Rdzanek, Wojciech P

2016-06-01

This study deals with the classical problem of sound radiation of an excited clamped circular plate embedded into a flat rigid baffle. The system of the two coupled differential equations is solved, one for the excited and damped vibrations of the plate and the other one-the Helmholtz equation. An approach using the expansion into radial polynomials leads to results for the modal impedance coefficients useful for a comprehensive numerical analysis of sound radiation. The results obtained are accurate and efficient in a wide low frequency range and can easily be adopted for a simply supported circular plate. The fluid loading is included providing accurate results in resonance.

A linear shock cell model for non-circular jets using conformal mapping with a pseudo-spectral hybrid scheme

NASA Technical Reports Server (NTRS)

Bhat, Thonse R. S.; Baty, Roy S.; Morris, Philip J.

1990-01-01

The shock structure in non-circular supersonic jets is predicted using a linear model. This model includes the effects of the finite thickness of the mixing layer and the turbulence in the jet shear layer. A numerical solution is obtained using a conformal mapping grid generation scheme with a hybrid pseudo-spectral discretization method. The uniform pressure perturbation at the jet exit is approximated by a Fourier-Mathieu series. The pressure at downstream locations is obtained from an eigenfunction expansion that is matched to the pressure perturbation at the jet exit. Results are presented for a circular jet and for an elliptic jet of aspect ratio 2.0. Comparisons are made with experimental data.

WIYN Open Cluster Study: Binary Orbits and Tidal Circularization in NGC 6819

NASA Astrophysics Data System (ADS)

Morscher, Meagan B.; Mathieu, R. D.; Kaeppler, S.; Hole, K. T.; Meibom, S.

2006-12-01

We are conducting a comprehensive stellar radial-velocity survey in NGC 6819, a rich, intermediate age ( 2.4 Gyr) open cluster with [Fe/H] -0.05. As of October 2006, we have obtained 7065 radial-velocity measurements of 1409 stars using the WIYN Hydra Multi-Object Spectrograph, with typical velocity measurement precisions of 0.4 km/s. Using an E/I criterion of 3, we have identified 282 velocity variables. In the past year we have expanded the number of final orbital solutions by 45 to a total of more than 80 solutions. In coeval stellar populations, circular binaries tend to have the shortest orbital periods, while longer period binaries show a distribution of non-zero eccentricities. The circularization of the shortest period orbits is the result of an exchange of stellar and orbital angular momentum due to tidal interactions. We defined a population’s tidal circularization period as the longest orbital period at which a binary of typical initial eccentricity has become circularized (e.g., has evolved to an eccentricity e = 0.01) over the lifetime of the cluster (Meibom & Mathieu, 2005, ApJ, 620, 970). We are studying the trend of increasing tidal circularization periods with population age. Preliminary results in NGC 6819 indicate a tidal circularization period of 7.5 days, which is consistent with this overall trend. We will recalculate the tidal circularization period in order to include the latest sample of orbital solutions. This comprehensive survey also allows us to investigate the relative spatial distributions of spectroscopic binaries and other constant-velocity cluster members of similar mass. We find the spectroscopic binaries to be more centrally concentrated at a statistically significant level, which we attribute to energy equipartition processes. MM was supported by REU NSF grant AST-0453442. RDM, SK, KTH, and SM were supported by NSF grant AST-0406615.

An integrated 3D log processing optimization system for small sawmills in central Appalachia

Treesearch

Wenshu Lin; Jingxin Wang

2013-01-01

An integrated 3D log processing optimization system was developed to perform 3D log generation, opening face determination, headrig log sawing simulation, fl itch edging and trimming simulation, cant resawing, and lumber grading. A circular cross-section model, together with 3D modeling techniques, was used to reconstruct 3D virtual logs. Internal log defects (knots)...

Application of a modified EDTA-mediated exudation technique and guttation fluid analysis for potato spindle tuber viroid RNA detection in tomato plants (Solanum lycopersicum)

USDA-ARS?s Scientific Manuscript database

Potato spindle tuber viroid (PSTVd) is a small plant pathogenic circular RNA that does not encode proteins, replicates autonomously, and traffics systemically in infected plants. Long-distance transport occurs by way of the phloem; however one report in the literature describes the presence of viroi...

Modelling low Reynolds number vortex-induced vibration problems with a fixed mesh fluid-solid interaction formulation

NASA Astrophysics Data System (ADS)

González Cornejo, Felipe A.; Cruchaga, Marcela A.; Celentano, Diego J.

2017-11-01

The present work reports a fluid-rigid solid interaction formulation described within the framework of a fixed-mesh technique. The numerical analysis is focussed on the study of a vortex-induced vibration (VIV) of a circular cylinder at low Reynolds number. The proposed numerical scheme encompasses the fluid dynamics computation in an Eulerian domain where the body is embedded using a collection of markers to describe its shape, and the rigid solid's motion is obtained with the well-known Newton's law. The body's velocity is imposed on the fluid domain through a penalty technique on the embedded fluid-solid interface. The fluid tractions acting on the solid are computed from the fluid dynamic solution of the flow around the body. The resulting forces are considered to solve the solid motion. The numerical code is validated by contrasting the obtained results with those reported in the literature using different approaches for simulating the flow past a fixed circular cylinder as a benchmark problem. Moreover, a mesh convergence analysis is also done providing a satisfactory response. In particular, a VIV problem is analyzed, emphasizing the description of the synchronization phenomenon.

Depth-resolved magnetic and structural analysis of relaxing epitaxial Sr 2 CrReO 6

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lucy, J. M.; Hauser, A. J.; Liu, Y.

2015-03-01

Structural relaxation in a Sr2CrReO6 epitaxial film, which exhibits strong spin-orbit coupling, leads to depth-dependent magnetism. We combine two depth-resolved synchrotron x-ray techniques, two-dimensional reciprocal space mapping and x-ray magnetic circular dichroism, to quantitatively determine this effect. An 800 nm thick film of Sr2CrReO6, grown with tensile epitaxial strain on SrCr0:5Nb0:5O3(225 nm)/LSAT, relaxes away from the Sr2CrReO6/SrCr0:5Nb0:5O3 interface to its bulk lattice parameters, with much of the film being fully relaxed. Grazing incidence xray diffraction measurements of the film elucidate the in-plane strain relaxation near the film- substrate interface while depth-resolved x-ray magnetic circular dichroism at the Re L edgemore » reveals the magnetic contributions of the Re site. The smooth relaxation of the film near the interface correlates with changes in the magnetic anisotropy. This provides a systematic and powerful way to probe the depth-varying structural and magnetic properties of a complex oxide with synchrotronsource x-ray techniques.« less

Investigation of guanosine-quartet assemblies by vibrational and electronic circular dichroism spectroscopy, a novel approach for studying supramolecular entities.

PubMed

Setnicka, Vladimír; Urbanová, Marie; Volka, Karel; Nampally, Sreenivasachary; Lehn, Jean-Marie

2006-11-24

The self-assembly of guanosine-5'-hydrazide G-1 in D(2)O, in the presence and absence of sodium cations, has been investigated by chiroptical techniques: electronic (ECD) and the newly introduced vibrational (VCD) circular dichroism spectroscopy. Using a combination of ECD and VCD with other methods such as IR, electron microscopy, and electrospray ionization mass spectrometry (ESI-MS) it was found that G-1 produces long-range chiral aggregates consisting of G-quartets, (G-1)(4), subsequently stacked into columns, [(G-1)(4)](n), induced by binding of metal cations between the (G-1)(4) species. This process, accompanied by gelation of the sample, is highly efficient in the presence of an excess of sodium cations, leading to aggregates with strong quartet-quartet interaction. Thermally induced conformational changes and conformational stability of guanosine-5'-hydrazide assemblies were studied by chiroptical techniques and the melting temperature of the hydrogels formed was obtained. The temperature-dependent experiments indicate that the long-range supramolecular aggregates are dissociated by increasing temperature into less ordered species, monomers, or other intermediates in equilibrium, as indicated by MS experiments.

Total mechanical stapled oesophagogastric anastomosis on the neck in oesophageal cancer - prevention of postoperative mediastinal complications.

PubMed

Zieliński, Jacek; Jaworski, Radosław; Irga-Jaworska, Ninela; Haponiuk, Ireneusz; Jaśkiewicz, Janusz

2015-12-01

Oesophagogastric anastomosis after oesophagus resection is commonly performed on the neck. Even though a few different techniques of oesophagogastric anastomosis have been previously detailed, both manual and mechanical procedures have been burdened with leakages and strictures. Our simple technique of oesophagogastric anastomosis is a modification of mechanical anastomosis with the use of a circular stapler in order to prevent postoperative leak and concomitant mediastinal complications. Since 2008, we have performed nine oesophagogastric anastomoses following oesophagus resection. The mean age of the operated patients was 54 years. There was no mortality among the operated patients in the early post-operative period. The mean follow-up period for the patients operated on in our department was 17 months until the time of the analysis. None of the patients showed any leakage or stricture, and no mediastinal complications were reported in the group. Following our own experience, mechanical anastomosis with the use of a circular stapler seems to decrease the time of the operation as well as significantly reducing the incidence of leakages from the anastomosis. This type of anastomosis may decrease the number of postoperative strictures and the most dangerous mediastinal infections.

Total mechanical stapled oesophagogastric anastomosis on the neck in oesophageal cancer – prevention of postoperative mediastinal complications

PubMed Central

Jaworski, Radosław; Irga-Jaworska, Ninela; Haponiuk, Ireneusz; Jaśkiewicz, Janusz

2015-01-01

Oesophagogastric anastomosis after oesophagus resection is commonly performed on the neck. Even though a few different techniques of oesophagogastric anastomosis have been previously detailed, both manual and mechanical procedures have been burdened with leakages and strictures. Our simple technique of oesophagogastric anastomosis is a modification of mechanical anastomosis with the use of a circular stapler in order to prevent postoperative leak and concomitant mediastinal complications. Since 2008, we have performed nine oesophagogastric anastomoses following oesophagus resection. The mean age of the operated patients was 54 years. There was no mortality among the operated patients in the early post-operative period. The mean follow-up period for the patients operated on in our department was 17 months until the time of the analysis. None of the patients showed any leakage or stricture, and no mediastinal complications were reported in the group. Following our own experience, mechanical anastomosis with the use of a circular stapler seems to decrease the time of the operation as well as significantly reducing the incidence of leakages from the anastomosis. This type of anastomosis may decrease the number of postoperative strictures and the most dangerous mediastinal infections. PMID:26855647

A three dimensional micropatterned tumor model for breast cancer cell migration studies.

PubMed

Peela, Nitish; Sam, Feba S; Christenson, Wayne; Truong, Danh; Watson, Adam W; Mouneimne, Ghassan; Ros, Robert; Nikkhah, Mehdi

2016-03-01

Breast cancer cell invasion is a highly orchestrated process driven by a myriad of complex microenvironmental stimuli, making it difficult to isolate and assess the effects of biochemical or biophysical cues (i.e. tumor architecture, matrix stiffness) on disease progression. In this regard, physiologically relevant tumor models are becoming instrumental to perform studies of cancer cell invasion within well-controlled conditions. Herein, we explored the use of photocrosslinkable hydrogels and a novel, two-step photolithography technique to microengineer a 3D breast tumor model. The microfabrication process enabled precise localization of cell-encapsulated circular constructs adjacent to a low stiffness matrix. To validate the model, breast cancer cell lines (MDA-MB-231, MCF7) and non-tumorigenic mammary epithelial cells (MCF10A) were embedded separately within the tumor model, all of which maintained high viability throughout the experiments. MDA-MB-231 cells exhibited extensive migratory behavior and invaded the surrounding matrix, whereas MCF7 or MCF10A cells formed clusters that stayed confined within the circular tumor regions. Additionally, real-time cell tracking indicated that the speed and persistence of MDA-MB-231 cells were substantially higher within the surrounding matrix compared to the circular constructs. Z-stack imaging of F-actin/α-tubulin cytoskeletal organization revealed unique 3D protrusions in MDA-MB-231 cells and an abundance of 3D clusters formed by MCF7 and MCF10A cells. Our results indicate that gelatin methacrylate (GelMA) hydrogel, integrated with the two-step photolithography technique, has great promise in the development of 3D tumor models with well-defined architecture and tunable stiffness. Copyright © 2015 Elsevier Ltd. All rights reserved.

Concept design and simulation study on a "phantom" anvil for circular stapler.

PubMed

Rulli, Francesco; Kartheuser, Alex; Amirhassankhani, Sasan; Mourad, Michel; Stefani, Mario; de Ferrá Aureli, Andrés; Sileri, Pierpaolo; Valentini, Pier Paolo

2015-04-01

Complications and challenges arising from the intraoperative double-stapling technique are seldom reported in colorectal surgery literature. Partial or full-thickness rectal injuries can occur during the introduction and the advancement of the circular stapler along the upper rectum. The aim of this study is to address some of these issues by designing and optimizing a "phantom" anvil manufactured to overcome difficulties throughout the rectal introduction and advancement of the circular stapler for the treatment of benign and malignant colon disease. The design of the "phantom" anvil has been performed using computer-aided modeling techniques, finite element investigations, and 2 essential keynotes in mind. The first one is the internal shape of the anvil, which is used for the connection to the gun. The second is the shape of the cap, which makes possible the insertion of the gun through the rectum. The "phantom" anvil has 2 functional requirements, which have been taken into account. The design has been optimized to avoid colorectal injuries, neoplastic dissemination (ie, mechanical seeding) and to reduce the fecal contamination. Numerical simulations show that a right combination of both top and bottom fillet radii of the shape of the anvil can reduce the stress for the considered anatomic configuration of >90%. Both the fillet radii at the top and the bottom of the device influence the local stress of the colon rectum. A dismountable device, which is used only for the insertion and advancement of the stapler, allows a dedicated design of its shape, keeping the remainder of the stapler unmodified. Computer-aided simulations are useful to perform numerical investigations to optimize the design of this auxiliary part for both the safety of the patient and the ease of the stapler advancement through the rectum.

Estimating non-circular motions in barred galaxies using numerical N-body simulations

NASA Astrophysics Data System (ADS)

Randriamampandry, T. H.; Combes, F.; Carignan, C.; Deg, N.

2015-12-01

The observed velocities of the gas in barred galaxies are a combination of the azimuthally averaged circular velocity and non-circular motions, primarily caused by gas streaming along the bar. These non-circular flows must be accounted for before the observed velocities can be used in mass modelling. In this work, we examine the performance of the tilted-ring method and the DISKFIT algorithm for transforming velocity maps of barred spiral galaxies into rotation curves (RCs) using simulated data. We find that the tilted-ring method, which does not account for streaming motions, under-/overestimates the circular motions when the bar is parallel/perpendicular to the projected major axis. DISKFIT, which does include streaming motions, is limited to orientations where the bar is not aligned with either the major or minor axis of the image. Therefore, we propose a method of correcting RCs based on numerical simulations of galaxies. We correct the RC derived from the tilted-ring method based on a numerical simulation of a galaxy with similar properties and projections as the observed galaxy. Using observations of NGC 3319, which has a bar aligned with the major axis, as a test case, we show that the inferred mass models from the uncorrected and corrected RCs are significantly different. These results show the importance of correcting for the non-circular motions and demonstrate that new methods of accounting for these motions are necessary as current methods fail for specific bar alignments.

Effects of finite ground plane on the radiation characteristics of a circular patch antenna

NASA Astrophysics Data System (ADS)

Bhattacharyya, Arun K.

1990-02-01

An analytical technique to determine the effects of finite ground plane on the radiation characteristics of a microstrip antenna is presented. The induced currents on the ground plane and on the upper surface of the patch are determined from the discontinuity of the near field produced by the equivalent magnetic current source on the physical aperture of the patch. The radiated fields contributed by the induced current on the ground plane and the equivalent sources on the physical aperture yield the radiation pattern of the antenna. Radiation patterns of the circular patch with finite ground plane size are computed and compared with the experimental data, and the agreement is found to be good. The radiation pattern, directive gain, and input impedance are found to vary widely with the ground plane size.

Spherical indentation of a freestanding circular membrane revisited: Analytical solutions and experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jin, Congrui; Davoodabadi, Ali; Li, Jianlin

Because of the development of novel micro-fabrication techniques to produce ultra-thin materials and increasing interest in thin biological membranes, in recent years, the mechanical characterization of thin films has received a significant amount of attention. To provide a more accurate solution for the relationship among contact radius, load and deflection, the fundamental and widely applicable problem of spherical indentation of a freestanding circular membrane have been revisited. The work presented here significantly extends the previous contributions by providing an exact analytical solution to the governing equations of Föppl–Hecky membrane indented by a frictionless spherical indenter. In this study, experiments ofmore » spherical indentation has been performed, and the exact analytical solution presented in this article is compared against experimental data from existing literature as well as our own experimental results.« less

Spherical indentation of a freestanding circular membrane revisited: Analytical solutions and experiments

DOE PAGES

Jin, Congrui; Davoodabadi, Ali; Li, Jianlin; ...

2017-01-11

Because of the development of novel micro-fabrication techniques to produce ultra-thin materials and increasing interest in thin biological membranes, in recent years, the mechanical characterization of thin films has received a significant amount of attention. To provide a more accurate solution for the relationship among contact radius, load and deflection, the fundamental and widely applicable problem of spherical indentation of a freestanding circular membrane have been revisited. The work presented here significantly extends the previous contributions by providing an exact analytical solution to the governing equations of Föppl–Hecky membrane indented by a frictionless spherical indenter. In this study, experiments ofmore » spherical indentation has been performed, and the exact analytical solution presented in this article is compared against experimental data from existing literature as well as our own experimental results.« less

Sound diffraction at wall impedance discontinuities in a circular cylinder, investigated using Wiener-Hopf technique

NASA Technical Reports Server (NTRS)

Cho, Y. C.

1983-01-01

Rigorous solutions are presented for sound diffraction in a circular cylinder with axial discontinuities of the wall admittance (or impedance). Analytical expressions are derived for the reflection and the transmission coefficients for duct modes. The results are discussed quantitatively in the limits of small admittance shifts (delta) and of low frequencies (ka). One of the results is the low frequency behavior of the reflection coefficient R(o) sub 00 of the fundamental mode. For the mode of a hardwall duct reflected from the junction with a softwall duct, (R(o) sub oo yields - (1-square root of (ka) square root of (2/i delta)); this result is in contrast to the frequency dependence of the reflection from the open end of a hardwall duct, for which R(o) sub oo yields - 1-(ka) squared/2 .

Detecting magnetic ordering with atomic size electron probes

DOE PAGES

Idrobo, Juan Carlos; Rusz, Ján; Spiegelberg, Jakob; ...

2016-05-27

While magnetism originates at the atomic scale, the existing spectroscopic techniques sensitive to magnetic signals only produce spectra with spatial resolution on a larger scale. However, recently, it has been theoretically argued that atomic size electron probes with customized phase distributions can detect magnetic circular dichroism. Here, we report a direct experimental real-space detection of magnetic circular dichroism in aberration-corrected scanning transmission electron microscopy (STEM). Using an atomic size-aberrated electron probe with a customized phase distribution, we reveal the checkerboard antiferromagnetic ordering of Mn moments in LaMnAsO by observing a dichroic signal in the Mn L-edge. The novel experimental setupmore » presented here, which can easily be implemented in aberration-corrected STEM, opens new paths for probing dichroic signals in materials with unprecedented spatial resolution.« less

An experimental trace gas investigation of fluid transport and mixing in a circular-to-rectangular transition duct

NASA Technical Reports Server (NTRS)

Reichert, B. A.; Hingst, W. R.; Okiishi, T. H.

1991-01-01

An ethylene trace gas technique was used to map out fluid transport and mixing within a circular to rectangular transition duct. Ethylene gas was injected at several points in a cross stream plane upstream of the transition duct. Ethylene concentration contours were determined at several cross stream measurement planes spaced axially within the duct. The flow involved a uniform inlet flow at a Mach number level of 0.5. Statistical analyses were used to quantitatively interpret the trace gas results. Also, trace gas data were considered along with aerodynamic and surface flow visualization results to ascertain transition duct flow phenomena. Convection of wall boundary layer fluid by vortices produced regions of high total pressure loss in the duct. The physical extent of these high loss regions is governed by turbulent diffusion.

A New Merit Function for Evaluating the Flaw Tolerance of Composite Laminates. Pt. 2; Arbitrary Size Holes and Center Cracks

NASA Technical Reports Server (NTRS)

Mikulas, Martin M., Jr.; Sumpter, Rod

1999-01-01

In a previous paper, a new merit function for determining the strength performance of flawed composite laminates was presented. This previous analysis was restricted to circular hole flaws that were large enough that failure could be predicted using the laminate stress concentration factor. In this paper, the merit function is expanded to include the flaw cases of an arbitrary size circular hole or a center crack. Failure prediction for these cases is determined using the point stress criterion. An example application of the merit function is included for a wide range of graphite/epoxy laminates.

A New Merit Function for Evaluating the Flaw Tolerance of Composite Laminates. Part 2; Arbitrary Size Holes and Center Cracks

NASA Technical Reports Server (NTRS)

Martin, Mikulas M., Jr.; Sumpter, Rod

2000-01-01

In a previous paper, a new merit function for determining the strength performance of flawed composite laminates was presented. This previous analysis was restricted to circular hole flaws that were large enough that failure could be predicted using the laminate stress concentration factor. In this paper, the merit function is expanded to include the flaw cases of an arbitrary size circular hole or center crack. Failure prediction for these cases is determined using the point stress criterion. An example application of the merit function is included for a wide range of graphite/epoxy laminates.

A New Merit Function for Evaluating the Flaw Tolerance of Composite Laminates. Part 2; Arbitrary Size Holes and Center Cracks

NASA Technical Reports Server (NTRS)

Mikulas, Martin M., Jr.; Sumpter, Rod

1997-01-01

In a previous paper, a new merit function for determining the strength performance of flawed composite laminates was presented. This previous analysis was restricted to circular hole flaws that were large enough that failure could be predicted using the laminate stress concentration factor. In this paper, the merit function is expanded to include the flaw cases of an arbitrary size circular hole or a center crack. Failure prediction for these cases is determined using the point stress criterion. An example application of the merit function is included for a wide range of graphite/epoxy laminates.

User's manual for FRAC3D: Supplement to report on stress analysis for structures with surface cracks

NASA Technical Reports Server (NTRS)

Bell, J. C.; Hopper, A. T.; Hayes, P. A.

1978-01-01

The FRAC3D computer program, designed for use in analyzing stresses in structures (including plates, bars, or blocks) which may contain part-circular surface cracks or embedded circular cracks is described. Instructions are provided for preparing input, including that for the supporting programs LATTICE and MATSOL as well as for FRAC3D. The course of a substantial illustrative calculation is shown with both input and output. The formulas underlying the calculations are summarized and related to the subroutines in which they are used. Many issues of strategy in using this program for analysing stresses around surface cracks are elucidated.

A Comparison of Trajectory Optimization Methods for the Impulsive Minimum Fuel Rendezvous Problem

NASA Technical Reports Server (NTRS)

Hughes, Steven P.; Mailhe, Laurie M.; Guzman, Jose J.

2002-01-01

In this paper we present a comparison of optimization approaches to the minimum fuel rendezvous problem. Both indirect and direct methods are compared for a variety of test cases. The indirect approach is based on primer vector theory. The direct approaches are implemented numerically and include Sequential Quadratic Programming (SQP), Quasi-Newton, Simplex, Genetic Algorithms, and Simulated Annealing. Each method is applied to a variety of test cases including, circular to circular coplanar orbits, LEO to GEO, and orbit phasing in highly elliptic orbits. We also compare different constrained optimization routines on complex orbit rendezvous problems with complicated, highly nonlinear constraints.

Multi-step splicing of sphingomyelin synthase linear and circular RNAs.

PubMed

Filippenkov, Ivan B; Sudarkina, Olga Yu; Limborska, Svetlana A; Dergunova, Lyudmila V

2018-05-15

The SGMS1 gene encodes the enzyme sphingomyelin synthase 1 (SMS1), which is involved in the regulation of lipid metabolism, apoptosis, intracellular vesicular transport and other significant processes. The SGMS1 gene is located on chromosome 10 and has a size of 320 kb. Previously, we showed that dozens of alternative transcripts of the SGMS1 gene are present in various human tissues. In addition to mRNAs that provide synthesis of the SMS1 protein, this gene participates in the synthesis of non-coding transcripts, including circular RNAs (circRNAs), which include exons of the 5'-untranslated region (5'-UTR) and are highly represented in the brain. In this study, using the high-throughput technology RNA-CaptureSeq, many new SGMS1 transcripts were identified, including both intronic unspliced RNAs (premature RNAs) and RNAs formed via alternative splicing. Recursive exons (RS-exons) that can participate in the multi-step splicing of long introns of the gene were also identified. These exons participate in the formation of circRNAs. Thus, multi-step splicing may provide a variety of linear and circular RNAs of eukaryotic genes in tissues. Copyright © 2018 Elsevier B.V. All rights reserved.

Numerical modeling of laser assisted tape winding process

NASA Astrophysics Data System (ADS)

Zaami, Amin; Baran, Ismet; Akkerman, Remko

2017-10-01

Laser assisted tape winding (LATW) has become more and more popular way of producing new thermoplastic products such as ultra-deep sea water riser, gas tanks, structural parts for aerospace applications. Predicting the temperature in LATW has been a source of great interest since the temperature at nip-point plays a key role for mechanical interface performance. Modeling the LATW process includes several challenges such as the interaction of optics and heat transfer. In the current study, numerical modeling of the optical behavior of laser radiation on circular surfaces is investigated based on a ray tracing and non-specular reflection model. The non-specular reflection is implemented considering the anisotropic reflective behavior of the fiber-reinforced thermoplastic tape using a bidirectional reflectance distribution function (BRDF). The proposed model in the present paper includes a three-dimensional circular geometry, in which the effects of reflection from different ranges of the circular surface as well as effect of process parameters on temperature distribution are studied. The heat transfer model is constructed using a fully implicit method. The effect of process parameters on the nip-point temperature is examined. Furthermore, several laser distributions including Gaussian and linear are examined which has not been considered in literature up to now.

Design of a Class of Antennas Utilizing MEMS, EBG and Septum Polarizers including Near-field Coupling Analysis

NASA Astrophysics Data System (ADS)

Kim, Ilkyu

Recent developments in mobile communications have led to an increased appearance of short-range communications and high data-rate signal transmission. New technologies provides the need for an accurate near-field coupling analysis and novel antenna designs. An ability to effectively estimate the coupling within the near-field region is required to realize short-range communications. Currently, two common techniques that are applicable to the near-field coupling problem are 1) integral form of coupling formula and 2) generalized Friis formula. These formulas are investigated with an emphasis on straightforward calculation and accuracy for various distances between the two antennas. The coupling formulas are computed for a variety of antennas, and several antenna configurations are evaluated through full-wave simulation and indoor measurement in order to validate these techniques. In addition, this research aims to design multi-functional and high performance antennas based on MEMS (Microelectromechanical Systems) switches, EBG (Electromagnetic Bandgap) structures, and septum polarizers. A MEMS switch is incorporated into a slot loaded patch antenna to attain frequency reconfigurability. The resonant frequency of the patch antenna can be shifted using the MEM switch, which is actuated by the integrated bias networks. Furthermore, a high gain base-station antenna utilizing beam-tilting is designed to maximize gain for tilted beam applications. To realize this base-station antenna, an array of four dipole-EBG elements is constructed to implement a fixed down-tilt main beam with application in base station arrays. An improvement of the operating range with the EBG-dipole array is evaluated using a simple linkbudget analysis. The septum polarizer has been widely used in circularly polarized antenna systems due to its simple and compact design and high quality of circularity. In this research, the sigmoid function is used to smoothen the edge in the septum design, which makes it suitable for HPM systems. The PSO (Particle Swarm Optimization) technique is applied to the septum design to achieve a high performance antenna design. The electric field intensity above the septum is evaluated through the simulation and its properties are compared to simple half-plane scattering phenomena.

Prediction techniques for jet-induced effects in hover on STOVL aircraft

NASA Technical Reports Server (NTRS)

Wardwell, Douglas A.; Kuhn, Richard E.

1991-01-01

Prediction techniques for jet induced lift effects during hover are available, relatively easy to use, and produce adequate results for preliminary design work. Although deficiencies of the current method were found, it is still currently the best way to estimate jet induced lift effects short of using computational fluid dynamics. Its use is summarized. The new summarized method, represents the first step toward the use of surface pressure data in an empirical method, as opposed to just balance data in the current method, for calculating jet induced effects. Although the new method is currently limited to flat plate configurations having two circular jets of equal thrust, it has the potential of more accurately predicting jet induced effects including a means for estimating the pitching moment in hover. As this method was developed from a very limited amount of data, broader applications of the method require the inclusion of new data on additional configurations. However, within this small data base, the new method does a better job in predicting jet induced effects in hover than the current method.

Treatment of close-range, low-velocity gunshot fractures of tibia and femur diaphysis with consecutive compression-distraction technique: a report of 11 cases.

PubMed

Ateşalp, A Sabri; Kömürcü, Mahmut; Demiralp, Bahtiyar; Bek, Dogan; Oğuz, Erbil; Yanmiş, Ibrahim

2004-01-01

Lower extremity injuries secondary to close-range, low-velocity gunshot wounds are frequently seen in both civilian and military populations. A close-range, low-velocity injury produces high energy and often results in comminuted and complicated fractures with significant morbidity. In this study, four femoral, four tibial, and three combined tibia and fibular comminuted diaphyseal fractures secondary to close-range, low-velocity gunshot wounds in 11 military personnel were treated with debridement followed by compression-distraction lengthening using a circular external fixator frame. Fracture union was obtained in all without significant major complications. Fracture consolidation occurred at a mean of 3.5 months. At follow-up of 46.8 months, there were no delayed unions, nonunions, or malunions. Minor complications included four pin-tract infections and knee flexion limitation in two femur fractures. Osteomyelitis and deep soft tissue infection were not observed. This technique provided an alternative to casting, open reduction internal fixation, or intermedullary fixation with an acceptable complication rate.

Combining spiral and target wave detection to analyze excitable media dynamics

NASA Astrophysics Data System (ADS)

Geberth, Daniel; Hütt, Marc-Thorsten

2010-01-01

Excitable media dynamics is the lossless active transmission of waves of excitation over a field of coupled elements, such as electrical excitation in heart tissue or nerve fibers, cAMP signaling in the slime mold Dictyostelium discoideum or waves of chemical activity in the Belousov-Zhabotinsky reaction. All these systems follow essentially the same generic dynamics, including undamped wave transmission and the self-organized emergence of circular target and self-sustaining spiral waves. We combine spiral recognition, using the established phase singularity technique, and a novel three-dimensional fitting algorithm for noise-resistant target wave recognition to extract all important events responsible for the layout of the asymptotic large-scale pattern. Space-time plots of these combined events reveal signatures of events leading to spiral formation, illuminating the microscopic mechanisms at work. This strategy can be applied to arbitrary excitable media data from either models or experiments, giving insight into for example the microscopic causes for formation of pathological spiral waves in heart tissue, which could lead to novel techniques for diagnosis, risk evaluation and treatment.

Theoretical evaluation of a V/STOL fighter model utilizing the PAN AIR code

NASA Technical Reports Server (NTRS)

Howell, G. A.; Bhateley, I. C.

1982-01-01

The PAN AIR computer code was investigated as a tool for predicting closely coupled aerodynamic and propulsive flowfields of arbitrary configurations. The NASA/Ames V/STOL fighter model, a configuration of complex geometry, was analyzed with the PAN AIR code. A successful solution for this configuration was obtained when the nozzle exit was treated as an impermeable surface and no wakes were included around the nozzle exit. When separated flow was simulated from the end of the nacelle, requiring the use of wake networks emanating from the nozzle exit, a number of problems were encountered. A circular body nacelle model was used to investigate various techniques for simulating the exhaust plume in PAN AIR. Several approaches were tested and eliminated because they could not correctly simulate the interference effects. Only one plume modeling technique gave good results. A PAN AIR computation that used a plume shape and inflow velocities obtained from the Navier-Stokes solution for the plume produced results for the effects of power that compared well with experimental data.

Synchrotron X-ray measurement techniques for thermal barrier coated cylindrical samples under thermal gradients.

PubMed

Siddiqui, Sanna F; Knipe, Kevin; Manero, Albert; Meid, Carla; Wischek, Janine; Okasinski, John; Almer, Jonathan; Karlsson, Anette M; Bartsch, Marion; Raghavan, Seetha

2013-08-01

Measurement techniques to obtain accurate in situ synchrotron strain measurements of thermal barrier coating systems (TBCs) applied to hollow cylindrical specimens are presented in this work. The Electron Beam Physical Vapor Deposition coated specimens with internal cooling were designed to achieve realistic temperature gradients over the TBC coated material such as that occurring in the turbine blades of aeroengines. Effects of the circular cross section on the x-ray diffraction (XRD) measurements in the various layers, including the thermally grown oxide, are investigated using high-energy synchrotron x-rays. Multiple approaches for beam penetration including collection, tangential, and normal to the layers, along with variations in collection parameters are compared for their ability to attain high-resolution XRD data from the internal layers. This study displays the ability to monitor in situ, the response of the internal layers within the TBC, while implementing a thermal gradient across the thickness of the coated sample. The thermal setup maintained coating surface temperatures in the range of operating conditions, while monitoring the substrate cooling, for a controlled thermal gradient. Through variation in measurement location and beam parameters, sufficient intensities are obtained from the internal layers which can be used for depth resolved strain measurements. Results are used to establish the various techniques for obtaining XRD measurements through multi-layered coating systems and their outcomes will pave the way towards goals in achieving realistic in situ testing of these coatings.

Synchrotron X-ray measurement techniques for thermal barrier coated cylindrical samples under thermal gradients

NASA Astrophysics Data System (ADS)

Siddiqui, Sanna F.; Knipe, Kevin; Manero, Albert; Meid, Carla; Wischek, Janine; Okasinski, John; Almer, Jonathan; Karlsson, Anette M.; Bartsch, Marion; Raghavan, Seetha

2013-08-01

Measurement techniques to obtain accurate in situ synchrotron strain measurements of thermal barrier coating systems (TBCs) applied to hollow cylindrical specimens are presented in this work. The Electron Beam Physical Vapor Deposition coated specimens with internal cooling were designed to achieve realistic temperature gradients over the TBC coated material such as that occurring in the turbine blades of aeroengines. Effects of the circular cross section on the x-ray diffraction (XRD) measurements in the various layers, including the thermally grown oxide, are investigated using high-energy synchrotron x-rays. Multiple approaches for beam penetration including collection, tangential, and normal to the layers, along with variations in collection parameters are compared for their ability to attain high-resolution XRD data from the internal layers. This study displays the ability to monitor in situ, the response of the internal layers within the TBC, while implementing a thermal gradient across the thickness of the coated sample. The thermal setup maintained coating surface temperatures in the range of operating conditions, while monitoring the substrate cooling, for a controlled thermal gradient. Through variation in measurement location and beam parameters, sufficient intensities are obtained from the internal layers which can be used for depth resolved strain measurements. Results are used to establish the various techniques for obtaining XRD measurements through multi-layered coating systems and their outcomes will pave the way towards goals in achieving realistic in situ testing of these coatings.

The Effect of Salts in Promoting Specific and Competitive Interactions between Zinc Finger Proteins and Metals

NASA Astrophysics Data System (ADS)

Li, Gongyu; Yuan, Siming; Zheng, Shihui; Chen, Yuting; Zheng, Zhen; Liu, Yangzhong; Huang, Guangming

2017-12-01

Specific protein-metal interactions (PMIs) fulfill essential functions in cells and organic bodies, and activation of these functions in vivo are mostly modulated by the complex environmental factors, including pH value, small biomolecules, and salts. Specifically, the role of salts in promoting specific PMIs and their competition among various metals has remained untapped mainly due to the difficulty to distinguish nonspecific PMIs from specific PMIs by classic spectroscopic techniques. Herein, we report Hofmeister salts differentially promote the specific PMIs by combining nanoelectrospray ionization mass spectrometry and spectroscopic techniques (fluorescence measurement and circular dichroism). Furthermore, to explore the influence of salts in competitive binding between metalloproteins and various metals, we designed a series of competitive experiments and applied to a well-defined model system, the competitive binding of zinc (II) and arsenic (III) to holo-promyelocytic leukemia protein (PML). These experiments not only provided new insights at the molecular scale as complementary to previous NMR and spectroscopic results, but also deduced the relative binding ability between zinc finger proteins and metals at the molecular scale, which avoids the mass spectrometric titration-based determination of binding constants that is frequently affected and often degraded by variable solution conditions including salt contents. [Figure not available: see fulltext.

Cancer of the rectum--sphincter-saving operation. Stapling techniques.

PubMed

Fazio, V W

1988-12-01

The techniques of restoring intestinal continuity after rectal resection for cancer have evolved throughout this century. For the most part, circular staplers have displaced the other pioneering and innovative techniques that our mentors and predecessors devised to improve the quality of life for our patients. With new technology, so also emerge new problems. Although the future likely will render many of our present techniques obsolete, for example, with refining of tissue adhesives, it is incumbent on us to recognize the limits of our present array of weapons and the limits placed on us by the biology of the tumor. About the latter, this means maintaining intellectual honesty in conducting a good cancer operation; about the former, we have to recognize that most of the pitfalls of stapling are preventable or correctable.

R-Type Ca2+ channels couple to inhibitory neurotransmission to the longitudinal muscle in the guinea-pig ileum.

PubMed

Rodriguez-Tapia, Eileen S; Naidoo, Vinogran; DeVries, Matthew; Perez-Medina, Alberto; Galligan, James J

2017-03-01

What is the central question of this study? Subtypes of enteric neurons are coded by the neurotransmitters they synthesize, but it is not known whether enteric neuron subtypes might also be coded by other proteins, including calcium channel subtypes controlling neurotransmitter release. What is the main finding and its importance? Our data indicate that guinea-pig ileum myenteric neuron subtypes may be coded by calcium channel subtypes. We found that R-type calcium channels are expressed by inhibitory but not excitatory longitudinal muscle motoneurons. R-Type calcium channels are also not expressed by circular muscle inhibitory motoneurons. Calcium channel subtype-selective antagonists could be used to target subtypes of neurons to treat gastrointestinal motility disorders. There is evidence that R-type Ca 2+ channels contribute to synaptic transmission in the myenteric plexus. It is unknown whether R-type Ca 2+ channels contribute to neuromuscular transmission. We measured the effects of the nitric oxide synthase inhibitor nitro-l-arginine (NLA), Ca 2+ channel blockers and apamin (SK channel blocker) on neurogenic relaxations and contractions of the guinea-pig ileum longitudinal muscle-myenteric plexus (LMMP) in vitro. We used intracellular recordings to measure inhibitory junction potentials. Immunohistochemical techniques localized R-type Ca 2+ channel protein in the LMMP and circular muscle. Cadmium chloride (pan-Ca 2+ channel blocker) blocked and NLA and NiCl 2 (R-type Ca 2+ channel blocker) reduced neurogenic relaxations in a non-additive manner. Nickel chloride did not alter neurogenic cholinergic contractions, but it potentiated neurogenic non-cholinergic contractions. Relaxations were inhibited by apamin, NiCl 2 and NLA and were blocked by combined application of these drugs. Relaxations were reduced by NiCl 2 or ω-conotoxin (N-type Ca 2+ channel blocker) and were blocked by combined application of these drugs. Longitudinal muscle inhibitory junction potentials were inhibited by NiCl 2 but not MRS 2179 (P2Y 1 receptor antagonist). Circular muscle inhibitory junction potentials were blocked by apamin, MRS 2179, ω-conotoxin and CdCl 2 but not NiCl 2 . We conclude that neuronal R-type Ca 2+ channels contribute to inhibitory neurotransmission to longitudinal muscle but less so or not all in the circular muscle of the guinea-pig ileum. © 2016 The Authors. Experimental Physiology © 2016 The Physiological Society.

Recombinant viral RdRps can initiate RNA synthesis from circular templates

PubMed Central

RANJITH-KUMAR, C.T.; KAO, C.C.

2006-01-01

The crystal structure of the recombinant hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp) revealed extensive interactions between the fingers and the thumb subdomains, resulting in a closed conformation with an established template channel that should specifically accept single-stranded templates. We made circularized RNA templates and found that they were efficiently used by the HCV RdRp to synthesize product RNAs that are significantly longer than the template, suggesting that RdRp could exist in an open conformation prior to template binding. RNA synthesis using circular RNA templates had properties similar to those previously documented for linear RNA, including a need for higher GTP concentration for initiation, usage of GTP analogs, sensitivity to salt, and involvement of active-site residues for product formation. Some products were resistant to challenge with the template competitor heparin, indicating that the elongation complexes remain bound to template and are competent for RNA synthesis. Other products were not elongated in the presence of heparin, indicating that the elongation complex was terminated. Lastly, recombinant RdRps from two other flaviviruses and from the Pseudomonas phage φ6 also could use circular RNA templates for RNA-dependent RNA synthesis, although the φ6 RdRp could only use circular RNAs made from the 3′-terminal sequence of the φ6 genome. PMID:16373481

Size-dependent axisymmetric vibration of functionally graded circular plates in bifurcation/limit point instability

NASA Astrophysics Data System (ADS)

Ashoori, A. R.; Vanini, S. A. Sadough; Salari, E.

2017-04-01

In the present paper, vibration behavior of size-dependent functionally graded (FG) circular microplates subjected to thermal loading are carried out in pre/post-buckling of bifurcation/limit-load instability for the first time. Two kinds of frequently used thermal loading, i.e., uniform temperature rise and heat conduction across the thickness direction are considered. Thermo-mechanical material properties of FG plate are supposed to vary smoothly and continuously throughout the thickness based on power law model. Modified couple stress theory is exploited to describe the size dependency of microplate. The nonlinear governing equations of motion and associated boundary conditions are extracted through generalized form of Hamilton's principle and von-Karman geometric nonlinearity for the vibration analysis of circular FG plates including size effects. Ritz finite element method is then employed to construct the matrix representation of governing equations which are solved by two different strategies including Newton-Raphson scheme and cylindrical arc-length method. Moreover, in the following a parametric study is accompanied to examine the effects of the several parameters such as material length scale parameter, temperature distributions, type of buckling, thickness to radius ratio, boundary conditions and power law index on the dimensionless frequency of post-buckled/snapped size-dependent FG plates in detail. It is found that the material length scale parameter and thermal loading have a significant effect on vibration characteristics of size-dependent circular FG plates.

FabricS: A user-friendly, complete and robust software for particle shape-fabric analysis

NASA Astrophysics Data System (ADS)

Moreno Chávez, G.; Castillo Rivera, F.; Sarocchi, D.; Borselli, L.; Rodríguez-Sedano, L. A.

2018-06-01

Shape-fabric is a textural parameter related to the spatial arrangement of elongated particles in geological samples. Its usefulness spans a range from sedimentary petrology to igneous and metamorphic petrology. Independently of the process being studied, when a material flows, the elongated particles are oriented with the major axis in the direction of flow. In sedimentary petrology this information has been used for studies of paleo-flow direction of turbidites, the origin of quartz sediments, and locating ignimbrite vents, among others. In addition to flow direction and its polarity, the method enables flow rheology to be inferred. The use of shape-fabric has been limited due to the difficulties of automatically measuring particles and analyzing them with reliable circular statistics programs. This has dampened interest in the method for a long time. Shape-fabric measurement has increased in popularity since the 1980s thanks to the development of new image analysis techniques and circular statistics software. However, the programs currently available are unreliable, old and are incompatible with newer operating systems, or require programming skills. The goal of our work is to develop a user-friendly program, in the MATLAB environment, with a graphical user interface, that can process images and includes editing functions, and thresholds (elongation and size) for selecting a particle population and analyzing it with reliable circular statistics algorithms. Moreover, the method also has to produce rose diagrams, orientation vectors, and a complete series of statistical parameters. All these requirements are met by our new software. In this paper, we briefly explain the methodology from collection of oriented samples in the field to the minimum number of particles needed to obtain reliable fabric data. We obtained the data using specific statistical tests and taking into account the degree of iso-orientation of the samples and the required degree of reliability. The program has been verified by means of several simulations performed using appropriately designed features and by analyzing real samples.

Inclined Bodies of Various Cross Sections at Supersonic Speeds

NASA Technical Reports Server (NTRS)

Jorgensen, Leland H.

1958-01-01

To aid in assessing effects of cross-sectional shape on body aerodynamics, the forces and moments have been measured for bodies with circular, elliptic, square, and triangular cross sections at Mach numbers 1.98 and 3.88. Results for bodies with noncircular cross sections have been compared with results for bodies of revolution having the same axial distribution of cross-sectional area (and, thus, the same equivalent fineness ratio). Comparisons have been made for bodies of fineness ratios 6 and 10 at angles of attack from 0 deg to about 20 deg and for Reynolds numbers, based on body length, of 4.0 x 10(exp 6) and 6.7 x 10(exp 6). The results of this investigation show that distinct aerodynamic advantages can be obtained by using bodies with noncircular cross sections. At certain angles of bank, bodies with elliptic, square, and triangular cross sections develop considerably greater lift and lift-drag ratios than equivalent bodies of revolution. For bodies with elliptic cross sections, lift and pitching-moment coefficients can be correlated with corresponding coefficients for equivalent circular bodies. It has been found that the ratios of lift and pitching-moment coefficients for an elliptic body to those for an equivalent circular body are practically constant with change in both angle of attack and Mach number. These lift and moment ratios are given very accurately by slender-body theory. As a result of this agreement, the method of NACA Rep. 1048 for computing forces and moments for bodies of revolution has been simply extended to bodies with elliptic cross sections. For the cases considered (elliptic bodies of fineness ratios 6 and 10 having cross-sectional axis ratios of 1.5 and 2), agreement of theory with experiment is very good. As a supplement to the force and moment results, visual studies of the flow over bodies have been made by use of the vapor-screen, sublimation, and white-lead techniques. Photographs from these studies are included in the report.

High-precision gauging of metal rings

NASA Astrophysics Data System (ADS)

Carlin, Mats; Lillekjendlie, Bjorn

1994-11-01

Raufoss AS designs and produces air brake fittings for trucks and buses on the international market. One of the critical components in the fittings is a small, circular metal ring, which is going through 100% dimension control. This article describes a low-price, high accuracy solution developed at SINTEF Instrumentation based on image metrology and a subpixel resolution algorithm. The measurement system consists of a PC-plugg-in transputer video board, a CCD camera, telecentric optics and a machine vision strobe. We describe the measurement technique in some detail, as well as the robust statistical techniques found to be essential in the real life environment.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Küchemann, Stefan; Mahn, Carsten; Samwer, Konrad

The investigation of short time dynamics using X-ray scattering techniques is commonly limited either by the read out frequency of the detector or by a low intensity. In this paper, we present a chopper system, which can increase the temporal resolution of 2D X-ray detectors by a factor of 13. This technique only applies to amorphous or polycrystalline samples due to their circular diffraction patterns. Using the chopper, we successfully increased the temporal resolution up to 5.1 ms during synchrotron experiments. For the construction, we provide a mathematical formalism, which, in principle, allows an even higher increase of the temporalmore » resolution.« less

An improved, robust, axial line singularity method for bodies of revolution

NASA Technical Reports Server (NTRS)

Hemsch, Michael J.

1989-01-01

The failures encountered in attempts to increase the range of applicability of the axial line singularity method for representing incompressible, inviscid flow about an inclined and slender body-of-revolution are presently noted to be common to all efforts to solve Fredholm equations of the first kind. It is shown that a previously developed smoothing technique yields a robust method for numerical solution of the governing equations; this technique is easily retrofitted to existing codes, and allows the number of circularities to be increased until the most accurate line singularity solution is obtained.

[Cervical mechanical anastomosis by transhiatal approach with a new circular stapler, Ehicon ECS 21].

PubMed

Gasparri, G; Casalegno, P A; Camandona, M; Moffa, F; Oliaro, A; Ferrero, V; Dei Poli, M

1996-12-01

Authors describe a new technique of mechanical cervical anastomosis using a new, particularly long, stapler, the ECS Ethicon. Mechanical anastomosis at neck level is difficult to perform with stapler now in use, so manual anastomosis is usually preferred. However the percentage of leakage is relatively high. The possibility of doing a mechanical anastomosis introducing the stapler through the pylorus is described. At the moment cases are too few to give a full evaluation of this new technique, but certainly it could be a valid alternative, safer and quicker, to manual anastomosis.

Analytical solutions to time-fractional partial differential equations in a two-dimensional multilayer annulus

NASA Astrophysics Data System (ADS)

Chen, Shanzhen; Jiang, Xiaoyun

2012-08-01

In this paper, analytical solutions to time-fractional partial differential equations in a multi-layer annulus are presented. The final solutions are obtained in terms of Mittag-Leffler function by using the finite integral transform technique and Laplace transform technique. In addition, the classical diffusion equation (α=1), the Helmholtz equation (α→0) and the wave equation (α=2) are discussed as special cases. Finally, an illustrative example problem for the three-layer semi-circular annular region is solved and numerical results are presented graphically for various kind of order of fractional derivative.

Non-intrusive investigation of flow and heat transfer characteristics of a channel with a built-in circular cylinder

NASA Astrophysics Data System (ADS)

Vyas, Apoorv; Mishra, Biswajit; Agrawal, Atul; Srivastava, Atul

2018-03-01

Interferometry-based experimental investigation of heat transfer phenomena associated with a channel fitted with a circular cylinder has been reported. Experiments have been performed with water as the working fluid, and the range of Reynolds number considered is 75 ≤ Re ≤ 165. The circular cylinder, placed at the inlet section of the channel, provides a blockage ratio of 0.5. The experimental methodology has been benchmarked against the results of transient numerical simulations. In order to assess the performance of the channel fitted with a circular cylinder for possible heat transfer enhancement from the channel wall(s), experiments have also been performed on a plane channel (without a cylinder). The interferometry-based experiments clearly highlighted the influence of the built-in cylinder in generating the flow instabilities and alterations in the thermal boundary layer profile along the heated wall of the channel. The phenomenon of vortex shedding behind the cylinder was successfully captured. A gradual increase in the vortex shedding frequency was observed with increasing Reynolds number. Quantitative data in the form of two-dimensional temperature distributions revealed an increase in the strength of wall thermal gradients in the wake region of the cylinder due to the periodic shedding of the vortices. In turn, a clear enhancement in the wall heat transfer rates was observed for the case of the channel fitted with a cylinder vis-à-vis the plane channel. To the best of the knowledge of the authors, the work reported is one of the first attempts to provide the planar field experimental data for a channel configuration with a built-in circular cylinder using non-intrusive imaging techniques and has the potential to serve as one of the benchmark studies for validating the existing as well as future numerical studies in the related area.

Planned secondary wound closure at the circular stapler insertion site after laparoscopic gastric bypass reduces postoperative morbidity, costs, and hospital stay.

PubMed

Vetter, Diana; Raptis, Dimitri Aristotle; Giama, Mira; Hosa, Hanna; Muller, Markus K; Nocito, Antonio; Schiesser, Marc; Moos, Rudolf; Bueter, Marco

2017-12-01

The aims of the present study were to assess whether planned secondary wound closure at the insertion site of the circular stapler reduces wound infection rate and postoperative morbidity after laparoscopic Roux-en-Y gastric bypass (RYGB) and to identify independent predictive factors increasing the risk for wound infections after RYGB. This paper is a retrospective single-center analysis of a prospectively collected database of 1400 patients undergoing RYGB surgery in circular technique between June 2000 and June 2016. Planned secondary wound closure at the circular stapler introduction site was performed at postoperative day 3 in 291 (20.8%) consecutive patients and compared to a historical control of 1109 (79.2%) consecutive patients with primary wound closure. Independent predictive factors for wound infection were assessed by multivariable analysis. Secondary wound closure significantly decreased wound infection rate from 9.3% (103/1109) to 1% (3/291) (p < 0.001) leading to a shorter hospital stay (mean 9 (SD8) vs. 7 days (SD2), p < 0.001), lower costs (p = 0.039), and reduced postoperative morbidity (mean 90-day Comprehensive Complication Index (CCI) 7.4 (SD14.0) vs. 5.1 (SD11.1) p = 0.008) when compared to primary wound closure. Primary wound closure, dyslipidemia, and preoperative gastritis were independent predictive risk factors for developing wound infections both in the univariate (p < 0.001; p = 0.048; p = 0.003) and multivariable analysis (p < 0.001; p = 0.040; p = 0.012). Further, on multivariable analysis, the female gender was a predictive factor (p = 0.034) for wound infection development. Secondary wound closure at the circular stapler introduction site in laparoscopic RYGB significantly reduces the overall wound infection rate as well as postoperative morbidity, costs, and hospital stay when compared to primary wound closure.

Heat Transfer Enhancement for Finned-tube Heat Exchangers with Winglets

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Brien, James Edward; Sohal, Manohar Singh

2000-11-01

This paper presents the results of an experimental study of forced convection heat transfer in a narrow rectangular duct fitted with a circular tube and/or a delta-winglet pair. The duct was designed to simulate a single passage in a fin-tube heat exchanger. Heat transfer measurements were obtained using a transient technique in which a heated airflow is suddenly introduced to the test section. High-resolution local fin-surface temperature distributions were obtained at several times after initiation of the transient using an imaging infrared camera. Corresponding local fin-surface heat transfer coefficient distributions were then calculated from a locally applied one-dimensional semi-infinite inversemore » heat conduction model. Heat transfer results were obtained over an airflow rate ranging from 1.51 x 10-3 to 14.0 x 10-3 kg/s. These flow rates correspond to a duct-height Reynolds number range of 670 – 6300 with a duct height of 1.106 cm and a duct width-toheight ratio, W/H, of 11.25. The test cylinder was sized such that the diameter-to-duct height ratio, D/H is 5. Results presented in this paper reveal visual and quantitative details of local fin-surface heat transfer distributions in the vicinity of a circular tube, a delta-winglet pair, and a combination of a circular tube and a delta-winglet pair. Comparisons of local and average heat transfer distributions for the circular tube with and without winglets are provided. Overall mean finsurface Nusselt-number results indicate a significant level of heat transfer enhancement associated with the deployment of the winglets with the circular cylinder. At the lowest Reynolds numbers (which correspond to the laminar operating conditions of existing geothermal air-cooled condensers), the enhancement level is nearly a factor of two. At higher Reynolds numbers, the enhancement level is close to 50%.« less

Shock tunnel studies of scramjet phenomena, supplement 5

NASA Technical Reports Server (NTRS)

Casey, R.; Stalker, R. J.; Brescianini, C. P.; Morgan, R. G.; Jacobs, P. A.; Wendt, M.; Ward, N. R.; Akman, N.; Allen, G. A.; Skinner, K.

1990-01-01

A series of reports are presented on SCRAMjet studies, shock tunnel studies, and expansion tube studies. The SCRAMjet studies include: (1) Investigation of a Supersonic Combustion Layer; (2) Wall Injected SCRAMjet Experiments; (3) Supersonic Combustion with Transvers, Circular, Wall Jets; (4) Dissociated Test Gas Effects on SCRAMjet Combustors; (5) Use of Silane as a Fuel Additive for Hypersonic Thrust Production, (6) Pressure-length Correlations in Supersonic Combustion; (7) Hot Hydrogen Injection Technique for Shock Tunnels; (8) Heat Release - Wave Interaction Phenomena in Hypersonic Flows; (9) A Study of the Wave Drag in Hypersonic SCRAMjets; (10) Parametric Study of Thrust Production in the Two Dimensional SCRAMjet; (11) The Design of a Mass Spectrometer for use in Hypersonic Impulse Facilities; and (12) Development of a Skin Friction Gauge for use in an Impulse Facility. The shock tunnel studies include: (1) Hypervelocity flow in Axisymmetric Nozzles; (2) Shock Tunnel Development; and (3) Real Gas Efects in Hypervelocity Flows over an Inclined Cone. The expansion tube studies include: (1) Investigation of Flow Characteristics in TQ Expansion Tube; and (2) Disturbances in the Driver Gas of a Shock Tube.