Leveraging Computer-Mediated Communication Technologies to Enhance Interactions in Online Learning

ERIC Educational Resources Information Center

Wright, Linda J.

2011-01-01

Computer-mediated communication (CMC) technologies have been an integral part of distance education for many years. They are found in both synchronous and asynchronous platforms and are intended to enhance the learning experience for students. CMC technologies add an interactive element to the online learning environment. The findings from this…

SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 6: Controls and guidance

NASA Technical Reports Server (NTRS)

1991-01-01

Viewgraphs of briefings from the Space Systems and Technology Advisory Committee (SSTAC)/ARTS review of the draft Integrated Technology Plan (ITP) on controls and guidance are included. Topics covered include: strategic avionics technology planning and bridging programs; avionics technology plan; vehicle health management; spacecraft guidance research; autonomous rendezvous and docking; autonomous landing; computational control; fiberoptic rotation sensors; precision instrument and telescope pointing; microsensors and microinstruments; micro guidance and control initiative; and earth-orbiting platforms controls-structures interaction.

Drug-drug interactions between anti-retroviral therapies and drugs of abuse in HIV systems.

PubMed

Kumar, Santosh; Rao, P S S; Earla, Ravindra; Kumar, Anil

2015-03-01

Substance abuse is a common problem among HIV-infected individuals. Importantly, addictions as well as moderate use of alcohol, smoking, or other illicit drugs have been identified as major reasons for non-adherence to antiretroviral therapy (ART) among HIV patients. The literature also suggests a decrease in the response to ART among HIV patients who use these substances, leading to failure to achieve optimal virological response and increased disease progression. This review discusses the challenges with adherence to ART as well as observed drug interactions and known toxicities with major drugs of abuse, such as alcohol, smoking, methamphetamine, cocaine, marijuana, and opioids. The lack of adherence and drug interactions potentially lead to decreased efficacy of ART drugs and increased ART, and drugs of abuse-mediated toxicity. As CYP is the common pathway in metabolizing both ART and drugs of abuse, we discuss the possible involvement of CYP pathways in such drug interactions. We acknowledge that further studies focusing on common metabolic pathways involving CYP and advance research in this area would help to potentially develop novel/alternate interventions and drug dose/regimen adjustments to improve medication outcomes in HIV patients who consume drugs of abuse.

Regulation of Androgen Receptor-Mediated Transcription by RPB5 Binding Protein URI/RMP ▿

PubMed Central

Mita, Paolo; Savas, Jeffrey N.; Djouder, Nabil; Yates, John R.; Ha, Susan; Ruoff, Rachel; Schafler, Eric D.; Nwachukwu, Jerome C.; Tanese, Naoko; Cowan, Nicholas J.; Zavadil, Jiri; Garabedian, Michael J.; Logan, Susan K.

2011-01-01

Androgen receptor (AR)-mediated transcription is modulated by interaction with coregulatory proteins. We demonstrate that the unconventional prefoldin RPB5 interactor (URI) is a new regulator of AR transcription and is critical for antagonist (bicalutamide) action. URI is phosphorylated upon androgen treatment, suggesting communication between the URI and AR signaling pathways. Whereas depletion of URI enhances AR-mediated gene transcription, overexpression of URI suppresses AR transcriptional activation and anchorage-independent prostate cancer cell growth. Repression of AR-mediated transcription is achieved, in part, by URI binding and regulation of androgen receptor trapped clone 27 (Art-27), a previously characterized AR corepressor. Consistent with this idea, genome-wide expression profiling in prostate cancer cells upon depletion of URI or Art-27 reveals substantially overlapping patterns of gene expression. Further, depletion of URI increases the expression of the AR target gene NKX-3.1, decreases the recruitment of Art-27, and increases AR occupancy at the NKX-3.1 promoter. While Art-27 can bind AR directly, URI is bound to chromatin prior to hormone-dependent recruitment of AR, suggesting a role for URI in modulating AR recruitment to target genes. PMID:21730289

Designing Digital Environments for Art Education/Exploration.

ERIC Educational Resources Information Center

Milekic, Slavko

2000-01-01

Examines the role of digital technology in the context of art education and art exploration. Discusses the development of digital environments as the next step in the evolution of traditional computers, whose main characteristic is support for simultaneous multiple-user interactions and for social and collaborative activities. (LRW)

Mn(ii) mediated degradation of artemisinin based on Fe3O4@MnSiO3-FA nanospheres for cancer therapy in vivo

NASA Astrophysics Data System (ADS)

Chen, Jian; Zhang, Weijie; Zhang, Min; Guo, Zhen; Wang, Haibao; He, Mengni; Xu, Pengping; Zhou, Jiajia; Liu, Zhenbang; Chen, Qianwang

2015-07-01

Artemisinin (ART) is a natural drug with potent anticancer activities related with Fe2+ mediated cleavage of the endoperoxide bridge in ART. Herein, we reported that Mn2+ could substitute for Fe2+ to react with ART and generate toxic products, inducing a much higher anticancer efficiency. On this basis, we prepared pH-responsive Fe3O4@MnSiO3-FA nanospheres which can efficiently deliver hydrophobic ART into tumors in mice models. Mn2+ was released in acidic tumor environments and intracellular lysosomes, interacting with ART to kill cancer cells. The ART-loaded nanocarriers could suppress tumor growth more efficiently than free ART, which could be further illustrated by magnetic resonance imaging (MRI). Histological analysis revealed that the drug delivery system had no obvious effect on the major organs of mice. ART has been reported to have lower toxicity than chemotherapeutics. The ART-loaded nanocarriers are promising to be used in improving the survival of chemotherapy patients, providing a novel method for clinical tumor therapy.Artemisinin (ART) is a natural drug with potent anticancer activities related with Fe2+ mediated cleavage of the endoperoxide bridge in ART. Herein, we reported that Mn2+ could substitute for Fe2+ to react with ART and generate toxic products, inducing a much higher anticancer efficiency. On this basis, we prepared pH-responsive Fe3O4@MnSiO3-FA nanospheres which can efficiently deliver hydrophobic ART into tumors in mice models. Mn2+ was released in acidic tumor environments and intracellular lysosomes, interacting with ART to kill cancer cells. The ART-loaded nanocarriers could suppress tumor growth more efficiently than free ART, which could be further illustrated by magnetic resonance imaging (MRI). Histological analysis revealed that the drug delivery system had no obvious effect on the major organs of mice. ART has been reported to have lower toxicity than chemotherapeutics. The ART-loaded nanocarriers are promising to be used in improving the survival of chemotherapy patients, providing a novel method for clinical tumor therapy. Electronic supplementary information (ESI) available: Iron mediated degradation mechanism for artemisinin, mechanism of alkylation of iron(ii)-heme or iron(ii)/heme dimethylester by artemisinin, mechanism of alkylation of the heme model MnIITPP by artemisinin, schematic illustration of the synthesis of ART-loaded Fe3O4@MnSiO3-FA nanospheres, further characterization such as XRD and EDX patterns, N2 adsorption and desorption isotherm and BJH pore distribution, FT-IR spectra, UV-vis spectra, DLS and parallel test results of flow cytometric detection are given in Fig. S1-S13, Fe2+ or Mn2+ release from Fe3O4@MnSiO3 nanospheres in PBS at different pHs is given in Table S1. See DOI: 10.1039/c5nr02402a

MOO: Using a Computer Gaming Environment to Teach about Community Arts

ERIC Educational Resources Information Center

Garber, Elizabeth

2004-01-01

In this paper, the author discusses the use of an interactive computer technology, "MOO" (Multi-user domain, Object-Oriented), in her art education classes for preservice teachers. A MOO is a text-based environment wherein interactivity is centered on text exchanges made between users based on problems or other materials created by teachers. The…

Spacecraft Charging Technology, 1980

NASA Technical Reports Server (NTRS)

1981-01-01

The third Spacecraft Charging Technology Conference proceedings contain 66 papers on the geosynchronous plasma environment, spacecraft modeling, charged particle environment interactions with spacecraft, spacecraft materials characterization, and satellite design and testing. The proceedings is a compilation of the state of the art of spacecraft charging and environmental interaction phenomena.

Preterm birth and Assisted Reproductive Technology/ART: maternal emotional wellbeing and quality of mother-newborn interaction during the first three months of life.

PubMed

Tallandini, Maria A; Morsan, Valentina; Macagno, Franco

2012-06-01

Assisted Reproductive Technology (ART) and premature birth are stressful and difficult experiences for women. No research to date has examined the impact of ART on mother-child relationship in instances of preterm delivery. This study explored the psychological status of preterm infants' ART-mothers and the quality of mother-infant dyadic interaction, up to child age of three months (Corrected Age = CA). Forty-one ART-dyads and 53 Spontaneous Pregnancy (SP) dyads were enrolled. Mother and child were assessed at 5 to 7 days after birth (T1), at child discharge from hospital (T2), at one month after discharge (T3); and at 3 months CA (T4). The following measures were administered to the mothers: the Gordon Personal Profile Inventory, the Beck Anxiety Inventory, the Beck Depression Inventory, and the Parenting Stress Index S-F. Mother-child interaction was coded by using the Nursing Child Assessment Feeding Scale. At childbirth, the control group mothers showed a higher level of anxiety than the ART-mothers did, but at T2, T3, T4, both groups' parenting stress levels were below threshold. Conversely, ART mothers more frequently provided suitable stimulation for their child's socio-emotional and cognitive development than the control group did. No significant between-group differences were observed in the mothers' capacity to respond to their children's distress, nor in sensitivity to child cues. Both infant groups showed equal ability to send clear signals and to respond to parent-provided care. ART and SP mothers with premature infants showed no differences in degree of emotional burden experienced during the neonatal period. Yet, dyadic interaction was qualitatively better in ART dyads than in SP dyads. Copyright © 2011 Elsevier Ltd. All rights reserved.

Thermal expression of intersubjectivity offers new possibilities to human–machine and technologically mediated interactions

PubMed Central

Merla, Arcangelo

2014-01-01

The evaluation of the psychophysiological state of the interlocutor is an important element of interpersonal relationships and communication. Thermal infrared (IR) imaging has proved to be a reliable tool for non-invasive and contact-less evaluation of vital signs, psychophysiological responses, and emotional states. This technique is quickly spreading in many fields, from psychometrics to social and developmental psychology; and from the touch-less monitoring of vital signs and stress, up to the human–machine interaction. In particular, thermal IR imaging promises to be of use for gathering information about affective states in social situations. This paper presents the state of the art of thermal IR imaging in psychophysiology and in the assessment of affective states. The goal is to provide insights about its potentialities and limits for its use in human–artificial agent interaction in order to contribute to a major issue in the field: the perception by an artificial agent of human psychophysiological and affective states. PMID:25101046

The Uses of Reason in Times of Technical Mediation.

PubMed

Dorrestijn, Steven

2017-01-01

The art of living idiom suits well a practice-oriented approach in ethics of technology. But what remains or becomes of the functioning and use of reason in ethics? In reaction to the comments by Huijer this reply elaborates in more detail how Foucault's art of living can be adapted for a critical contemporary ethics of technology. And the aesthetic-political rationality in Foucault's ethics is compared with Wellner's suggestions of holding on to the notion of code but with a new meaning. Foucault's fourfold scheme of subjectivation and a distinction of "below and above reason" structure the argument.

Drug–drug interactions between anti-retroviral therapies and drugs of abuse in HIV systems

PubMed Central

Rao, PSS; Earla, Ravindra; Kumar, Anil

2015-01-01

Introduction Substance abuse is a common problem among HIV-infected individuals. Importantly, addictions as well as moderate use of alcohol, smoking, or other illicit drugs have been identified as major reasons for non-adherence to antiretroviral therapy (ART) among HIV patients. The literature also suggests a decrease in the response to ART among HIV patients who use these substances, leading to failure to achieve optimal virological response and increased disease progression. Areas covered This review discusses the challenges with adherence to ART as well as observed drug interactions and known toxicities with major drugs of abuse, such as alcohol, smoking, methamphetamine, cocaine, marijuana, and opioids. The lack of adherence and drug interactions potentially lead to decreased efficacy of ART drugs and increased ART, and drugs of abuse-mediated toxicity. As CYP is the common pathway in metabolizing both ART and drugs of abuse, we discuss the possible involvement of CYP pathways in such drug interactions. Expert opinion We acknowledge that further studies focusing on common metabolic pathways involving CYP and advance research in this area would help to potentially develop novel/alternate interventions and drug dose/regimen adjustments to improve medication outcomes in HIV patients who consume drugs of abuse. PMID:25539046

Web 2.0 Technologies and Parent Involvement of ELL Students: An Ecological Perspective

ERIC Educational Resources Information Center

Shin, Dong-shin; Seger, Wendy

2016-01-01

This study explores how ELL students' parents participated in a blog-mediated English language arts curriculum in a second grade classroom at a U.S. urban school, and how they supported their children's learning of school-based writing. Adopting ecological perspectives on technological affordances, this study views digital literacy as discursive…

The Impact of Developing Technology on Media Communications.

ERIC Educational Resources Information Center

MacDonald, Lindsay W.

1997-01-01

Examines changes in media communications resulting from new information technologies: communications technologies (networks, World Wide Web, digital set-top box); graphic arts (digital photography, CD and digital archives, desktop design and publishing, printing technology); television and video (digital editing, interactive television, news and…

[Lights, art, science - action!].

PubMed

Lopes, Thelma

2005-01-01

The article offers some reflections on the main interactions between theater, science, and technology down through the history of theater. Based on our experience at "Science in the Spotlight", part of the Casa de Oswaldo Cruz's Museum of Life, we discuss how these interactions can be part of a science museum's daily activities. We use the word 'science' in its broad sense, encompassing not only the natural but human sciences as well; likewise, we use the word 'technology' as it relates to applied science. Art and science are understood here as creative processes, as ways of representing the world and expressing human knowledge.

Virtual art revisited

NASA Astrophysics Data System (ADS)

Ruzanka, S.

2014-02-01

Virtual reality art at the turn of the millenium saw an explosion of creative exploration around this nascent technoloy. Though VR art has much in common with media art in general, the affordances of the technology gave rise to unique experiences, discourses, and artistic investigations. Women artists were at the forefront of the medium, shaping its aesthetic and technical development, and VR fostered a range of artistic concerns and experimentation that was largely distinct from closely related forms such as digital games. Today, a new wave of consumer technologies including 3D TV's, gestural and motion tracking interfaces, and headmount displays as viable, low-cost gaming peripherals drives a resurgence in interest in VR for interactive art and entertainment. Designers, game developers, and artists working with these technologies are in many cases discovering them anew. This paper explores ways of reconnecting this current moment in VR with its past. Can the artistic investigations begun in previous waves of VR be continued? How do the similarities and differences in contexts, communities, technologies, and discourses affect the development of the medium?

Spacecraft Environmental Interactions Technology, 1983

NASA Technical Reports Server (NTRS)

1985-01-01

State of the art of environment interactions dealing with low-Earth-orbit plasmas; high-voltage systems; spacecraft charging; materials effects; and direction of future programs are contained in over 50 papers.

ELM-ART--An Interactive and Intelligent Web-Based Electronic Textbook

ERIC Educational Resources Information Center

Weber, Gerhard; Brusilovsky, Peter

2016-01-01

This paper present provides a broader view on ELM-ART, one of the first Web-based Intelligent Educational systems that offered a creative combination of two different paradigms--Intelligent Tutoring and Adaptive Hypermedia technologies. The unique dual nature of ELM-ART contributed to its long life and research impact and was a result of…

Structural basis of ubiquitin modification by the Legionella effector SdeA.

PubMed

Dong, Yanan; Mu, Yajuan; Xie, Yongchao; Zhang, Yupeng; Han, Youyou; Zhou, Yu; Wang, Wenhe; Liu, Zihe; Wu, Mei; Wang, Hao; Pan, Man; Xu, Ning; Xu, Cong-Qiao; Yang, Maojun; Fan, Shilong; Deng, Haiteng; Tan, Tianwei; Liu, Xiaoyun; Liu, Lei; Li, Jun; Wang, Jiawei; Fang, Xianyang; Feng, Yue

2018-05-01

Protein ubiquitination is a multifaceted post-translational modification that controls almost every process in eukaryotic cells. Recently, the Legionella effector SdeA was reported to mediate a unique phosphoribosyl-linked ubiquitination through successive modifications of the Arg42 of ubiquitin (Ub) by its mono-ADP-ribosyltransferase (mART) and phosphodiesterase (PDE) domains. However, the mechanisms of SdeA-mediated Ub modification and phosphoribosyl-linked ubiquitination remain unknown. Here we report the structures of SdeA in its ligand-free, Ub-bound and Ub-NADH-bound states. The structures reveal that the mART and PDE domains of SdeA form a catalytic domain over its C-terminal region. Upon Ub binding, the canonical ADP-ribosyltransferase toxin turn-turn (ARTT) and phosphate-nicotinamide (PN) loops in the mART domain of SdeA undergo marked conformational changes. The Ub Arg72 might act as a 'probe' that interacts with the mART domain first, and then movements may occur in the side chains of Arg72 and Arg42 during the ADP-ribosylation of Ub. Our study reveals the mechanism of SdeA-mediated Ub modification and provides a framework for further investigations into the phosphoribosyl-linked ubiquitination process.

Elementary School Industrial Arts Interaction Technology for Children. A Positive Approach to Education for a Changing Society.

ERIC Educational Resources Information Center

Louisiana State Dept. of Education, Baton Rouge.

Prepared by the vocational education division of a state department of education and compiled by industrial arts educators, this resource guide provides a conceptual basis for the elementary teacher using industrial arts as a means of introducing children to industrial processes and orienting them to the physical and material world. Included in…

Eye Tracking and Head Movement Detection: A State-of-Art Survey

PubMed Central

2013-01-01

Eye-gaze detection and tracking have been an active research field in the past years as it adds convenience to a variety of applications. It is considered a significant untraditional method of human computer interaction. Head movement detection has also received researchers' attention and interest as it has been found to be a simple and effective interaction method. Both technologies are considered the easiest alternative interface methods. They serve a wide range of severely disabled people who are left with minimal motor abilities. For both eye tracking and head movement detection, several different approaches have been proposed and used to implement different algorithms for these technologies. Despite the amount of research done on both technologies, researchers are still trying to find robust methods to use effectively in various applications. This paper presents a state-of-art survey for eye tracking and head movement detection methods proposed in the literature. Examples of different fields of applications for both technologies, such as human-computer interaction, driving assistance systems, and assistive technologies are also investigated. PMID:27170851

Assessing Team Learning in Technology-Mediated Collaboration: An Experimental Study

ERIC Educational Resources Information Center

Andres, Hayward P.; Akan, Obasi H.

2010-01-01

This study examined the effects of collaboration mode (collocated versus non-collocated videoconferencing-mediated) on team learning and team interaction quality in a team-based problem solving context. Situated learning theory and the theory of affordances are used to provide a framework that describes how technology-mediated collaboration…

Creative and Computational Thinking in the Context of New Literacies: Working with Teachers to Scaffold Complex Technology-Mediated Approaches to Teaching and Learning

ERIC Educational Resources Information Center

DeSchryver, Michael D.; Yadav, Aman

2015-01-01

For too long, creativity in schools has been almost solely associated with art, music, and writing classes. Now, creative thinking skills are increasingly emphasized across the disciplines. At the same time, technological progress has brought about calls for the integration of new literacies and computational thinking to prepare students as…

Galaxy Classroom Project Evaluation, Language Arts, Grades 3-5. Final Report.

ERIC Educational Resources Information Center

Guth, Gloria J. A.; Block, Clifford

The GALAXY Language Arts Demonstration Program is a package of integrated curricular and instructional approaches that features the organization of instruction around themes presented through television broadcasts, children's literature, classroom activities, and the use of interactive technology. During the GALAXY Project demonstration phase for…

Robot-assisted gait training for stroke patients: current state of the art and perspectives of robotics.

PubMed

Morone, Giovanni; Paolucci, Stefano; Cherubini, Andrea; De Angelis, Domenico; Venturiero, Vincenzo; Coiro, Paola; Iosa, Marco

2017-01-01

In this review, we give a brief outline of robot-mediated gait training for stroke patients, as an important emerging field in rehabilitation. Technological innovations are allowing rehabilitation to move toward more integrated processes, with improved efficiency and less long-term impairments. In particular, robot-mediated neurorehabilitation is a rapidly advancing field, which uses robotic systems to define new methods for treating neurological injuries, especially stroke. The use of robots in gait training can enhance rehabilitation, but it needs to be used according to well-defined neuroscientific principles. The field of robot-mediated neurorehabilitation brings challenges to both bioengineering and clinical practice. This article reviews the state of the art (including commercially available systems) and perspectives of robotics in poststroke rehabilitation for walking recovery. A critical revision, including the problems at stake regarding robotic clinical use, is also presented.

Robot-assisted gait training for stroke patients: current state of the art and perspectives of robotics

PubMed Central

Morone, Giovanni; Paolucci, Stefano; Cherubini, Andrea; De Angelis, Domenico; Venturiero, Vincenzo; Coiro, Paola; Iosa, Marco

2017-01-01

In this review, we give a brief outline of robot-mediated gait training for stroke patients, as an important emerging field in rehabilitation. Technological innovations are allowing rehabilitation to move toward more integrated processes, with improved efficiency and less long-term impairments. In particular, robot-mediated neurorehabilitation is a rapidly advancing field, which uses robotic systems to define new methods for treating neurological injuries, especially stroke. The use of robots in gait training can enhance rehabilitation, but it needs to be used according to well-defined neuroscientific principles. The field of robot-mediated neurorehabilitation brings challenges to both bioengineering and clinical practice. This article reviews the state of the art (including commercially available systems) and perspectives of robotics in poststroke rehabilitation for walking recovery. A critical revision, including the problems at stake regarding robotic clinical use, is also presented. PMID:28553117

Development and application of a recombination-based library versus library high- throughput yeast two-hybrid (RLL-Y2H) screening system.

PubMed

Yang, Fang; Lei, Yingying; Zhou, Meiling; Yao, Qili; Han, Yichao; Wu, Xiang; Zhong, Wanshun; Zhu, Chenghang; Xu, Weize; Tao, Ran; Chen, Xi; Lin, Da; Rahman, Khaista; Tyagi, Rohit; Habib, Zeshan; Xiao, Shaobo; Wang, Dang; Yu, Yang; Chen, Huanchun; Fu, Zhenfang; Cao, Gang

2018-02-16

Protein-protein interaction (PPI) network maintains proper function of all organisms. Simple high-throughput technologies are desperately needed to delineate the landscape of PPI networks. While recent state-of-the-art yeast two-hybrid (Y2H) systems improved screening efficiency, either individual colony isolation, library preparation arrays, gene barcoding or massive sequencing are still required. Here, we developed a recombination-based 'library vs library' Y2H system (RLL-Y2H), by which multi-library screening can be accomplished in a single pool without any individual treatment. This system is based on the phiC31 integrase-mediated integration between bait and prey plasmids. The integrated fragments were digested by MmeI and subjected to deep sequencing to decode the interaction matrix. We applied this system to decipher the trans-kingdom interactome between Mycobacterium tuberculosis and host cells and further identified Rv2427c interfering with the phagosome-lysosome fusion. This concept can also be applied to other systems to screen protein-RNA and protein-DNA interactions and delineate signaling landscape in cells.

Perceptions of Talk, Text, Transactions, and Technology: Preservice Teachers, CMC, and Reader Response

ERIC Educational Resources Information Center

Akers, Anne Trice Thompson

2009-01-01

This qualitative study examined middle grades preservice language arts teachers' perceptions of young adult literature through the lenses of reader response, new literacy, and activity theory. Undergraduate preservice teachers used synchronous and asynchronous computer-mediated communication (CMC) to respond online to three young adult books with…

Ordering competition: the interactional accomplishment of the sale of art and antiques at auction.

PubMed

Heath, Christian; Luff, Paul

2007-03-01

Auctions provide an institutional solution to a social problem; they enable the legitimate pricing and exchange of goods where those goods are of uncertain value. In turn, auctions raise a number of social and organizational issues that are resolved within the interaction that arise in sales by auction. In this paper, we examine sales of fine art, antiques and objets d'art and explore the ways in which auctioneers mediate competition between buyers and establish a value for goods. In particular, we explore how bids are elicited, co-ordinated and revealed so as to rapidly escalate the price of goods in a transparent manner that enables the legitimate valuation and exchange of goods. In directing attention towards the significance of the social interaction, including talk, visual and material conduct, the paper contributes to the growing corpus of ethnographic studies of markets. It suggests that to understand the operation of markets and their outcomes, and to unpack issues of agency, trust and practice, we need to place the 'interaction order' at the heart of analytic agenda.

New Global Art Connection: Paying Tribute to the Wave-Makers (1910-2010)

ERIC Educational Resources Information Center

Kan, Koon Hwee

2013-01-01

This paper highlights "Wave-Makers (1910--2010)", a collaborative timeline redesign project, which involves interactive and advanced web-based technology to connect and complement arts curricula at two higher education institutions, one located in China and another in the United States. Through in-depth research, video-conferencing,…

Autism and Digital Learning Environments: Processes of Interaction and Mediation

ERIC Educational Resources Information Center

Passerino, Liliana M.; Santarosa, Lucila M. Costi

2008-01-01

Using a socio-historical perspective to explain social interaction and taking advantage of information and communication technologies (ICTs) currently available for creating digital learning environments (DLEs), this paper seeks to redress the absence of empirical data concerning technology-aided social interaction between autistic individuals. In…

Methods of Technological Forecasting,

DTIC Science & Technology

1977-05-01

Trend Extrapolation Progress Curve Analogy Trend Correlation Substitution Analysis or Substitution Growth Curves Envelope Curve Advances in the State of...the Art Technological Mapping Contextual Mapping Matrix Input-Output Analysis Mathematical Models Simulation Models Dynamic Modelling. CHAPTER IV...Generation Interaction between Needs and Possibilities Map of the Technological Future — (‘ross- Impact Matri x Discovery Matrix Morphological Analysis

Abstraction and art.

PubMed Central

Gortais, Bernard

2003-01-01

In a given social context, artistic creation comprises a set of processes, which relate to the activity of the artist and the activity of the spectator. Through these processes we see and understand that the world is vaster than it is said to be. Artistic processes are mediated experiences that open up the world. A successful work of art expresses a reality beyond actual reality: it suggests an unknown world using the means and the signs of the known world. Artistic practices incorporate the means of creation developed by science and technology and change forms as they change. Artists and the public follow different processes of abstraction at different levels, in the definition of the means of creation, of representation and of perception of a work of art. This paper examines how the processes of abstraction are used within the framework of the visual arts and abstract painting, which appeared during a period of growing importance for the processes of abstraction in science and technology, at the beginning of the twentieth century. The development of digital platforms and new man-machine interfaces allow multimedia creations. This is performed under the constraint of phases of multidisciplinary conceptualization using generic representation languages, which tend to abolish traditional frontiers between the arts: visual arts, drama, dance and music. PMID:12903659

Abstraction and art.

PubMed

Gortais, Bernard

2003-07-29

In a given social context, artistic creation comprises a set of processes, which relate to the activity of the artist and the activity of the spectator. Through these processes we see and understand that the world is vaster than it is said to be. Artistic processes are mediated experiences that open up the world. A successful work of art expresses a reality beyond actual reality: it suggests an unknown world using the means and the signs of the known world. Artistic practices incorporate the means of creation developed by science and technology and change forms as they change. Artists and the public follow different processes of abstraction at different levels, in the definition of the means of creation, of representation and of perception of a work of art. This paper examines how the processes of abstraction are used within the framework of the visual arts and abstract painting, which appeared during a period of growing importance for the processes of abstraction in science and technology, at the beginning of the twentieth century. The development of digital platforms and new man-machine interfaces allow multimedia creations. This is performed under the constraint of phases of multidisciplinary conceptualization using generic representation languages, which tend to abolish traditional frontiers between the arts: visual arts, drama, dance and music.

It Is Risky Business: Three Essays on Ensuring Reliability, Security and Privacy in Technology-Mediated Settings

ERIC Educational Resources Information Center

Anderson, Catherine L.

2010-01-01

Today's interconnected technical environment creates unprecedented opportunities while simultaneously introducing risks. With economic, social and personal interactions increasingly occurring in technology-mediated settings new vulnerabilities are continually being introduced. This dissertation seeks to improve extant understanding of how…

Copyright Considerations in Distance Education and Technology-Mediated Instruction.

ERIC Educational Resources Information Center

Salomon, Kenneth D.

The accelerating development of distance education and the use of technology-mediated instructional materials over interactive computer networks has given rise to heightened interest and thought by faculty and administration alike about related copyright issues. The evolution of distance education from early morning television broadcasts to…

Learning without Boundaries: Developing Mobile Learning Scenarios for Elementary and Middle School Language Arts & Mathematics

ERIC Educational Resources Information Center

Evans, Michael A.; Gracanin, Denis

2009-01-01

This article provides an overview to a collaborative knowledge building project using iPod Touches in elementary and secondary language arts and mathematics classrooms, working with 4 teachers and over 80 students. The interactive technologies for embodied Learning in Reading and Mathematics (iteL*RM) project intends to facilitate student…

Hypermediated Art Criticism

ERIC Educational Resources Information Center

Taylor, Pamela G.; Carpenter, B. Stephen, II

2007-01-01

Technological media catapults our perception into what Marshall McLuhan called "new transforming vision and awareness." As our lives become more and more immersed in such technologies as television, film, and interactive computers, we find ourselves inundated with a heightened sense of mindfulness--an aesthetic experience made possible through…

CALL from an Ecological Perspective: How a Teacher Perceives Affordance and Fosters Learner Agency in a Technology-Mediated Language Classroom

ERIC Educational Resources Information Center

Liu, Qian; Chao, Chin-Chi

2018-01-01

The possibility of exploiting technology for more robust and meaningful learning and teaching has invoked messianic responses from the language education community. Yet to be explored are teachers' pedagogical choices based on the perceived technological affordances as well as interactions between teacher and student agency mediated by these…

Drawing Lines with Light in Holographic Space

NASA Astrophysics Data System (ADS)

Chang, Yin-Ren; Richardson, Martin

2013-02-01

This paper explores the dynamic and expressive possibilities of holographic art through a comparison of art history and technical media such as photography, film and holographic technologies. Examples of modern art and creative expression of time and motions are examined using the early 20th century art movement, Cubism, where subjects are portrayed to be seen simultaneously from different angles. Folding space is represented as subject matter as it can depict space from multiple points of time. The paper also investigates the way holographic art has explored time and space. The lenticular lens-based media reveal a more subjective poetic art in the form of the lyrical images and messages as spectators pass through time, or walk along with the piece of work through an interactive process. It is argued that photographic practice is another example of artistic representation in the form of aesthetic medium of time movement and as such shares a common ground with other dynamic expression that require time based interaction.

Acetylcholine Neuromodulation in Normal and Abnormal Learning and Memory: Vigilance Control in Waking, Sleep, Autism, Amnesia and Alzheimer’s Disease

PubMed Central

Grossberg, Stephen

2017-01-01

Adaptive Resonance Theory, or ART, is a neural model that explains how normal and abnormal brains may learn to categorize and recognize objects and events in a changing world, and how these learned categories may be remembered for a long time. This article uses ART to propose and unify the explanation of diverse data about normal and abnormal modulation of learning and memory by acetylcholine (ACh). In ART, vigilance control determines whether learned categories will be general and abstract, or specific and concrete. ART models how vigilance may be regulated by ACh release in layer 5 neocortical cells by influencing after-hyperpolarization (AHP) currents. This phasic ACh release is mediated by cells in the nucleus basalis (NB) of Meynert that are activated by unexpected events. The article additionally discusses data about ACh-mediated tonic control of vigilance. ART proposes that there are often dynamic breakdowns of tonic control in mental disorders such as autism, where vigilance remains high, and medial temporal amnesia, where vigilance remains low. Tonic control also occurs during sleep-wake cycles. Properties of Up and Down states during slow wave sleep arise in ACh-modulated laminar cortical ART circuits that carry out processes in awake individuals of contrast normalization, attentional modulation, decision-making, activity-dependent habituation, and mismatch-mediated reset. These slow wave sleep circuits interact with circuits that control circadian rhythms and memory consolidation. Tonic control properties also clarify how Alzheimer’s disease symptoms follow from a massive structural degeneration that includes undermining vigilance control by ACh in cortical layers 3 and 5. Sleep disruptions before and during Alzheimer’s disease, and how they contribute to a vicious cycle of plaque formation in layers 3 and 5, are also clarified from this perspective. PMID:29163063

Bringing the Community Along: A Case Study of a School District's Information Technology Rural Development Initiative

ERIC Educational Resources Information Center

Schafft, Kai A.; Alter, Theodore R.; Bridger, Jeffrey C.

2006-01-01

We draw on interactional community theory to analyze the relationship between information technology and local development through a case study of a geographically isolated and economically disadvantaged rural school district. This district has used state-of-the-art information technology infrastructure in a broad-based community and economic…

Natural Interaction Based Online Military Boxing Learning System

ERIC Educational Resources Information Center

Yang, Chenglei; Wang, Lu; Sun, Bing; Yin, Xu; Wang, Xiaoting; Liu, Li; Lu, Lin

2013-01-01

Military boxing, a kind of Chinese martial arts, is widespread and health beneficial. In this paper, the authors introduce a military boxing learning system realized by 3D motion capture, Web3D and 3D interactive technologies. The interactions with the system are natural and intuitive. Users can observe and learn the details of each action of the…

Technology for large space systems: A special bibliography with indexes (supplement 03)

NASA Technical Reports Server (NTRS)

1980-01-01

A bibliography containing 217 abstracts addressing the technology for large space systems is presented. State of the art and advanced concepts concerning interactive analysis and design, structural concepts, control systems, electronics, advanced materials, assembly concepts, propulsion, solar power satellite systems, and flight experiments are represented.

Using immersive media and digital technology to communicate Earth Science

NASA Astrophysics Data System (ADS)

Kapur, Ravi

2016-04-01

A number of technologies in digital media and interactivity have rapidly advanced and are now converging to enable rich, multi-sensoral experiences which create opportunities for both digital art and science communication. Techniques used in full-dome film-making can now be deployed in virtual reality experiences; gaming technologies can be utilised to explore real data sets; and collaborative interactivity enable new forms of public artwork. This session will explore these converging trends through a number of emerging and forthcoming projects dealing with Earth science, climate change and planetary science.

Impact of pharmacy technician-centered medication reconciliation on optimization of antiretroviral therapy and opportunistic infection prophylaxis in hospitalized patients with HIV/AIDS.

PubMed

Siemianowski, Laura A; Sen, Sanchita; George, Jomy M

2013-08-01

This study aimed to examine the role of a pharmacy technician-centered medication reconciliation (PTMR) program in optimization of medication therapy in hospitalized patients with HIV/AIDS. A chart review was conducted for all inpatients that had a medication reconciliation performed by the PTMR program. Adult patients with HIV and antiretroviral therapy (ART) and/or the opportunistic infection (OI) prophylaxis listed on the medication reconciliation form were included. The primary objective is to describe the (1) number and types of medication errors and (2) the percentage of patients who received appropriate ART. The secondary objective is a comparison of the number of medication errors between standard mediation reconciliation and a pharmacy-led program. In the PTMR period, 55 admissions were evaluated. In all, 50% of the patients received appropriate ART. In 27of the 55 admissions, there were 49 combined ART and OI-related errors. The most common ART-related errors were drug-drug interactions. The incidence of ART-related medication errors that included drug-drug interactions and renal dosing adjustments were similar between the pre-PTMR and PTMR groups (P = .0868). Of the 49 errors in the PTMR group, 18 were intervened by a medication reconciliation pharmacist. A PTMR program has a positive impact on optimizing ART and OI prophylaxis in patients with HIV/AIDS.

Activity Theory and Technology Mediated Interaction: Cognitive Scaffolding Using Question-Based Consultation on "Facebook"

ERIC Educational Resources Information Center

Rambe, Patient

2012-01-01

Studies that employed activity theory as a theoretical lens for exploring computer-mediated interaction have not adopted social media as their object of study. However, social media provides lecturers with personalised learning environments for diagnostic and prognostic assessments of student mastery of content and deep learning. The integration…

Interpersonal and intrapersonal factors as parallel independent mediators in the association between internalized HIV stigma and ART adherence

PubMed Central

Seghatol-Eslami, Victoria C.; Dark, Heather; Raper, James L.; Mugavero, Michael J.; Turan, Janet M.; Turan, Bulent

2016-01-01

Introduction People living with HIV (PLWH) need to adhere to antiretroviral therapy (ART) to achieve optimal health. One reason for ART non-adherence is HIV-related stigma. Objectives We aimed to examine whether HIV treatment self-efficacy (an intrapersonal mechanism) mediates the stigma – adherence association. We also examined whether self-efficacy and the concern about being seen while taking HIV medication (an interpersonal mechanism) are parallel mediators independent of each other. Methods 180 PLWH self-reported internalized HIV stigma, ART adherence, HIV treatment self-efficacy, and concerns about being seen while taking HIV medication. We calculated bias-corrected 95% confidence intervals (CIs) for indirect effects using bootstrapping to conduct mediation analyses. Results Adherence self-efficacy mediated the relationship between internalized stigma and ART adherence. Additionally, self-efficacy and concern about being seen while taking HIV medication uniquely mediated and explained almost all of the stigma – adherence association in independent paths (parallel mediation). Conclusion These results can inform intervention strategies to promote ART adherence. PMID:27926668

Rethinking the Question of Quality in Art.

ERIC Educational Resources Information Center

Ewens, Thomas

1994-01-01

Discusses the concept of quality in art from the standpoint of the theory of mediation. Traces the idea of quality from Aristotelian criticism to Gagnepain's theory of mediation. Concludes that mediation aesthetics seek inspiration and quality only from the art work, not its contemporary meaning. (CFR)

Does infertility history affect the emotional adjustment of couples undergoing assisted reproduction? the mediating role of the importance of parenthood.

PubMed

Moura-Ramos, Mariana; Gameiro, Sofia; Canavarro, Maria Cristina; Soares, Isabel; Almeida-Santos, Teresa

2016-05-01

The emotional adjustment of couples undergoing assisted reproductive technology (ART) treatments has been widely studied; however, it remains unclear whether infertility history contributes to couples' adjustment. This study examined the impact of infertility history (duration of infertility and number of previous ART treatment cycles) on the emotional adjustment of couples undergoing an ART cycle and the mediating effect of importance of parenthood on that association. In this cross-sectional study, 70 infertile couples (70 women and 70 men) completed self-report questionnaires assessing emotional adjustment and infertility stress during the hormonal stimulation phase of an ART cycle. Path models accounting for the dyadic nature of the data examined the direct and indirect effects (by affecting representations about parenthood and childlessness) of infertility history on emotional adjustment. The number of previous cycles affected men's, but not women's, emotional adjustment by affecting the representations on the importance of parenthood and of childlessness. Duration of infertility had the opposite effect, as couples with longer infertility reported heightened importance of parenthood, which negatively affected their emotional adjustment. Infertility history was associated with emotional adjustment in men and women, although these associations were complex. The results suggest that progression through treatment is harder for those men and women who attribute higher importance to being parents, which is aggravated by longer infertility. What is already known about the subject? Infertility is an unexpected and stressful life event Assisted reproductive treatments (ART) are emotionally demanding What does this study add? The influence of infertility history on adjustment is mediated by the importance of parenthood Men and women are affected by their past history of infertility differently. © 2015 The Authors. British Journal of Health Psychology published by John Wiley & Sons Ltd on behalf of British Psychological Society.

The costs and consequences of assisted reproductive technology: an economic perspective.

PubMed

Connolly, Mark P; Hoorens, Stijn; Chambers, Georgina M

2010-01-01

Despite the growing use of assisted reproductive technologies (ART) worldwide, there is only a limited understanding of the economics of ART to inform policy about effective, safe and equitable financing of ART treatment. A review was undertaken of key studies regarding the costs and consequences of ART treatment, specifically examining the direct and indirect costs of treatment, economic drivers of utilization and clinical practice and broader economic consequences of ART-conceived children. The direct costs of ART treatment vary substantially between countries, with the USA standing out as the most expensive. The direct costs generally reflect the costliness of the underlying healthcare system. If unsubsidized, direct costs represent a significant economic burden to patients. The level of affordability of ART treatment is an important driver of utilization, treatment choices, embryo transfer practices and ultimately multiple birth rates. The costs associated with caring for multiple-birth ART infants and their mothers are substantial, reflecting the underlying morbidity associated with such pregnancies. Investment analysis of ART treatment and ART-conceived children indicates that appropriate funding of ART services appears to represent sound fiscal policy. The complex interaction between the cost of ART treatment and how treatments are subsidized in different healthcare settings and for different patient groups has far-reaching consequences for ART utilization, clinical practice and infant outcomes. A greater understanding of the economics of ART is needed to inform policy decisions and to ensure the best possible outcomes from ART treatment.

MDR1 and BCRP Transporter-Mediated Drug-Drug Interaction between Rilpivirine and Abacavir and Effect on Intestinal Absorption

PubMed Central

Reznicek, Josef; Ceckova, Martina; Ptackova, Zuzana; Martinec, Ondrej; Tupova, Lenka; Cerveny, Lukas

2017-01-01

ABSTRACT Rilpivirine (TMC278) is a highly potent nonnucleoside reverse transcriptase inhibitor (NNRTI) representing an effective component of combination antiretroviral therapy (cART) in the treatment of HIV-positive patients. Many antiretroviral drugs commonly used in cART are substrates of ATP-binding cassette (ABC) and/or solute carrier (SLC) drug transporters and, therefore, are prone to pharmacokinetic drug-drug interactions (DDIs). The aim of our study was to evaluate rilpivirine interactions with abacavir and lamivudine on selected ABC and SLC transporters in vitro and assess its importance for pharmacokinetics in vivo. Using accumulation assays in MDCK cells overexpressing selected ABC or SLC drug transporters, we revealed rilpivirine as a potent inhibitor of MDR1 and BCRP, but not MRP2, OCT1, OCT2, or MATE1. Subsequent transport experiments across monolayers of MDCKII-MDR1, MDCKII-BCRP, and Caco-2 cells demonstrated that rilpivirine inhibits MDR1- and BCRP-mediated efflux of abacavir and increases its transmembrane transport. In vivo experiments in male Wistar rats confirmed inhibition of MDR1/BCRP in the small intestine, leading to a significant increase in oral bioavailability of abacavir. In conclusion, rilpivirine inhibits MDR1 and BCRP transporters and may affect pharmacokinetic behavior of concomitantly administered substrates of these transporters, such as abacavir. PMID:28696229

CompuLung: a multimedia CBL on pulmonary auscultation.

PubMed Central

Mangione, S.; Dennis, S.

1992-01-01

Cardio-pulmonary auscultation, a time honored art, is suffering a declining interest caused by competing diagnostic technology and inadequate training of physicians. Overreliance on diagnostic technology is expensive, not cost-effective and bound to lead to loss of our clinical heritage. We need novel methods to teach and revive this art. Computer-Based Learning (CBL), particularly multimedia supporting graphics plus sound-and-motion pictures, appears to be ideally suited for teaching and sharpening this skill. We present in this paper a multimedia CBL ("CompuLung"), that provides the user with a comprehensive and interactive tutorial on pulmonary auscultation. PMID:1482999

Caring in a Technology-Mediated Online High School Context

ERIC Educational Resources Information Center

Velasquez, Andrea; Graham, Charles R.; Osguthorpe, Richard

2013-01-01

The objective of this study was to describe how caring is experienced in the technology-mediated context of the Open High School in Utah, an online charter high school. Two female teachers, two male students, and two female students were interviewed three times over 9 months regarding their experience of caring teacher-student interactions. Data…

Colloquium: Digital Technologies--Help or Hindrance for the Humanities?

ERIC Educational Resources Information Center

Barker, Elton; Bissell, Chris; Hardwick, Lorna; Jones, Allan; Ridge, Mia; Wolffe, John

2012-01-01

This article offers reflections arising from a recent colloquium at the Open University on the implications of the development of digital humanities for research in arts disciplines, and also for their interactions with computing and technology. Particular issues explored include the ways in which the digital turn in humanities research is also a…

Graphics Tablet Technology in Second Year Thermal Engineering Teaching

ERIC Educational Resources Information Center

Carrillo, Antonio; Cejudo, José Manuel; Domínguez, Fernando; Rodríguez, Eduardo

2013-01-01

Graphics tablet technology is well known in markets such as manufacturing, graphics arts and design but it has not yet found widespread acceptance for university teaching. A graphics tablet is an affordable teaching tool that combines the best features from traditional and new media. It allows developing a progressive, interactive lecture (as a…

E-service learning: A pedagogic innovation for healthcare management education.

PubMed

Malvey, Donna M; Hamby, Eileen F; Fottler, Myron D

2006-01-01

This paper proposes an innovation in service learning that we identify as e-service learning. By adding the "e" to service learning, we create a service learning model that is dynamic, mediated by technology, and delivered online. This paper begins by examining service learning, which is a distinct learning concept. Service learning furnishes students with opportunities for applied learning through participation in projects and activities in community organizations. The authors then define and conceptualize e-service learning, including the anticipated outcomes of implementation such as enhanced access, quality, and cost effectiveness of healthcare management education. Because e-service learning is mediated by technology, we identify state of the art technologies that support e-service learning activities. In addition, possible e-service learning projects and activities that may be included in healthcare management courses such as finance, human resources, quality, service management/marketing and strategy are identified. Finally, opportunities for future research are suggested.

On Mediation in Virtual Learning Environments.

ERIC Educational Resources Information Center

Davies, Larry; Hassan, W. Shukry

2001-01-01

Discusses concepts of mediation and focuses on the importance of implementing comprehensive virtual learning environments. Topics include education and technology as they relate to cultural change, social institutions, the Internet and computer-mediated communication, software design and human-computer interaction, the use of MOOs, and language.…

Fostering Computer-Mediated L2 Interaction beyond the Classroom

ERIC Educational Resources Information Center

Barrs, Keith

2012-01-01

In language learning contexts a primary concern is how to maximise target language interaction both inside and outside of the classroom. With the development of digital technologies, the proliferation of language learning applications, and an increased awareness of how technology can assist in language education, educators are being presented with…

Technological Pedagogical Content Knowledge Preparedness of Student-Teachers of the Department of Arts and Social Sciences Education of University of Cape Coast

ERIC Educational Resources Information Center

Apau, Stephen Kwakye

2017-01-01

The proliferation of digital technology in the 21st century in teaching and learning requires that teachers and students constantly interact with instructional technologies. This places a herculean task on the door step of teacher educators to ensure that student-teachers graduate from their institutions of training with some knowledge domains…

Mobile Learning: Technology as Mediator of Personal and School Experiences

ERIC Educational Resources Information Center

Duvall, Matthew; Matranga, Anthony; Foster, Aroutis; Silverman, Jason

2016-01-01

This study reports on the effects of a mobile game designed in conjunction with an art museum to develop children's understanding of line, shape, and color. Four researchers (two graduate students and two professors at a private university in the mid-Atlantic region of the United States) examined 8 children, ages 6 to 13, for conceptual change in…

Computer-mediated interdisciplinary teams: theory and reality.

PubMed

Vroman, Kerryellen; Kovacich, Joann

2002-05-01

The benefit of experience, tempered with the wisdom of hindsight and 5 years of text-based, asynchronous, computer-mediated, interdisciplinary team communications, provides the energy, insights and data shared in this article. Through the theoretical lens of group dynamics and the epistemology of interdisciplinary teaming, we analyze the interactions of a virtual interdisciplinary team to provide an understanding and appreciation of collaborative interdisciplinary communication in the context of interactive technologies. Whilst interactive technologies may require new patterns of language similar to that of learning a foreign language, what is communicated in the interdisciplinary team process does not change. Most important is the recognition that virtual teams, similar to their face-to-face counterparts, undergo the same challenges of interdisciplinary teaming and group developmental processes of formation: forming, storming, norming, performing, and transforming. After examining these dynamics of communication and collaboration in the context of the virtual team, the article concludes with guidelines facilitating interdisciplinary team computer-mediated communication.

Side effects, adherence self-efficacy, and adherence to antiretroviral treatment: a mediation analysis in a Chinese sample.

PubMed

Zhang, Liying; Li, Xiaoming; Lin, Zhenping; Jacques-Tiura, Angela J; Xu, Jinping; Zhou, Yuejiao; Qiao, Shan; Shen, Zhiyong; Stanton, Bonita

2016-07-01

Antiretroviral therapy (ART) is a lifelong treatment. To date, ART adherence is suboptimal for most patients in resource-poor settings. Previous research indicates that medication side effects are perceived to be a significant barrier of high ART adherence. Data regarding the role of adherence self-efficacy in mediating the relationship between side effects from ART and adherence to ART are limited; thus, this study examines this potential mediational role of self-efficacy. A cross-sectional survey of 2987 people living with HIV aged ≥18 years was conducted in 2012-2013 in Guangxi Autonomous Region (Guangxi) which has one of the fastest-growing HIV rates in China. Of the total sample, 2146 (72.1%) participants had initiated ART. Participants reported the number of days of completing the daily dose of ART in the past month; adherence was defined as completing the daily dose at least 28 days in the last month (≥90%). Side effects were significantly negatively related to adherence to ART. Mediation analyses indicated that adherence self-efficacy significantly mediated the side effects-adherence relationship. Future interventions to increase adherence self-efficacy and effective coping with side effects among HIV patients are needed in order to improve their ART adherence.

Learning Methods for Efficient Adoption of Contemporary Technologies in Architectural Design

ERIC Educational Resources Information Center

Mahdavinejad, Mohammadjavad; Dehghani, Sohaib; Shahsavari, Fatemeh

2013-01-01

The interaction between technology and history is one of the most significant issues in achieving an efficient and progressive architecture in any era. This is a concept which stems from lesson of traditional architecture of Iran. Architecture as a part of art, has permanently been transforming just like a living organism. In fact, it has been…

State-of-the-Art Model Driven Game Development: A Survey of Technological Solutions for Game-Based Learning

ERIC Educational Resources Information Center

Tang, Stephen; Hanneghan, Martin

2011-01-01

Game-based learning harnesses the advantages of computer games technology to create a fun, motivating and interactive virtual learning environment that promotes problem-based experiential learning. Such an approach is advocated by many commentators to provide an enhanced learning experience than those based on traditional didactic methods.…

Capturing Change: Integrating Art and Science

NASA Astrophysics Data System (ADS)

Gillerman, J.

2011-12-01

The evolving capabilities of interactive media have broadened the potential, and the challenges, of sharing scientific knowledge. From video capture to mobile devices, new technologies have enabled artists to tackle previously demanding or out-of-reach topics and new avenues of dissemination of both art and science. These changes and capabilities affect not only the context and possibilities of scientific data collection, but also how information is presented and communicated innovatively to the public. When recording video of science material whether it is of a Ridley Sea Turtle laying eggs on a beach in Costa Rica, an active lava flow from the volcano Kilauea in Hawaii, or solar eclipses in remote locations around the world, one has to be prepared technically and artistically, not to mention patient in specialized and/or challenging conditions to capture video that satisfies the scientific and artistic imagination. This presentation will include material from varied natural phenomena, creative interfacing in a multimedia context integrating art, science, culture and technology to reach a broad and diverse public, and teaching the integration of art and science through varied art media. (http://www.vipervertex.com).

Study of auxiliary propulsion requirements for large space systems, volume 2

NASA Technical Reports Server (NTRS)

Smith, W. W.; Machles, G. W.

1983-01-01

A range of single shuttle launched large space systems were identified and characterized including a NASTRAN and loading dynamics analysis. The disturbance environment, characterization of thrust level and APS mass requirements, and a study of APS/LSS interactions were analyzed. State-of-the-art capabilities for chemical and ion propulsion were compared with the generated propulsion requirements to assess the state-of-the-art limitations and benefits of enhancing current technology.

Epic Allies: Development of a Gaming App to Improve Antiretroviral Therapy Adherence Among Young HIV-Positive Men Who Have Sex With Men.

PubMed

LeGrand, Sara; Muessig, Kathryn Elizabeth; McNulty, Tobias; Soni, Karina; Knudtson, Kelly; Lemann, Alex; Nwoko, Nkechinyere; Hightow-Weidman, Lisa B

2016-05-13

In the United States, the human immunodeficiency virus (HIV) disproportionately affects young men who have sex with men (YMSM). For HIV-positive individuals, adherence to antiretroviral therapy (ART) is critical for achieving optimal health outcomes and reducing secondary transmission of HIV. However, YMSM often struggle with ART adherence. Novel mobile phone apps that incorporate game-based mechanics and social networking elements represent a promising intervention approach for improving ART adherence among YMSM. This study used a multiphase, iterative development process to create an ART adherence app for YMSM. The three-phase development process included: (1) theory-based concept development jointly by public health researchers and the technology team, (2) assessment of the target population's ART adherence needs and app preferences and development and testing of a clickable app prototype, and (3) development and usability testing of the final app prototype. The initial theory-based app concept developed in Phase One included medication reminders, daily ART adherence tracking and visualization, ART educational modules, limited virtual interactions with other app users, and gamification elements. In Phase Two, adherence needs, including those related to information, motivation, and behavioral skills, were identified. Participants expressed preferences for an ART adherence app that was informational, interactive, social, and customizable. Based on the findings from Phase Two, additional gaming features were added in Phase Three, including an interactive battle, superhero app theme, and app storyline. Other features were modified to increase interactivity and customization options and integrate the game theme. During usability testing of the final prototype, participants were able to understand and navigate the app successfully and rated the app favorably. An iterative development process was critical for the development of an ART adherence game app that was viewed as highly acceptable, relevant, and useful by YMSM.

Epic Allies: Development of a Gaming App to Improve Antiretroviral Therapy Adherence Among Young HIV-Positive Men Who Have Sex With Men

PubMed Central

Muessig, Kathryn Elizabeth; McNulty, Tobias; Soni, Karina; Knudtson, Kelly; Lemann, Alex; Nwoko, Nkechinyere; Hightow-Weidman, Lisa B

2016-01-01

Background In the United States, the human immunodeficiency virus (HIV) disproportionately affects young men who have sex with men (YMSM). For HIV-positive individuals, adherence to antiretroviral therapy (ART) is critical for achieving optimal health outcomes and reducing secondary transmission of HIV. However, YMSM often struggle with ART adherence. Novel mobile phone apps that incorporate game-based mechanics and social networking elements represent a promising intervention approach for improving ART adherence among YMSM. Objective This study used a multiphase, iterative development process to create an ART adherence app for YMSM. Methods The three-phase development process included: (1) theory-based concept development jointly by public health researchers and the technology team, (2) assessment of the target population’s ART adherence needs and app preferences and development and testing of a clickable app prototype, and (3) development and usability testing of the final app prototype. Results The initial theory-based app concept developed in Phase One included medication reminders, daily ART adherence tracking and visualization, ART educational modules, limited virtual interactions with other app users, and gamification elements. In Phase Two, adherence needs, including those related to information, motivation, and behavioral skills, were identified. Participants expressed preferences for an ART adherence app that was informational, interactive, social, and customizable. Based on the findings from Phase Two, additional gaming features were added in Phase Three, including an interactive battle, superhero app theme, and app storyline. Other features were modified to increase interactivity and customization options and integrate the game theme. During usability testing of the final prototype, participants were able to understand and navigate the app successfully and rated the app favorably. Conclusions An iterative development process was critical for the development of an ART adherence game app that was viewed as highly acceptable, relevant, and useful by YMSM. PMID:27178752

Chronic effects of ethanol and/or darunavir/ritonavir on U937 monocytic cells: Regulation of cytochrome P450 and antioxidant enzymes, oxidative stress, and cytotoxicity

PubMed Central

Rao, P.S.S.; Kumar, Santosh

2015-01-01

Background Our recent study has shown that acute treatment with ethanol increases oxidative stress and cytotoxicity through cytochrome P450 2E1 (CYP2E1)-mediated pathway in U937 monocytic cells. U937 cells are derived from blood monocytes and are considered as the model system for HIV-related study. Since the prevalence of alcohol use in HIV-infected population is high, and HIV+ patients are on antiretroviral therapy (ART) soon after they are diagnosed, it is important to study the interactions between ethanol and ART in monocytes. Methods This study examined the chronic effects of ethanol and ART (darunavir/ritonavir), alone and in combination, on expression/levels of cytochrome P450 enzymes (CYPs), antioxidant enzymes (AOEs), reactive oxygen species (ROS), and cytotoxicity in U937 cells. The mRNA and protein levels were measured using quantitative RTPCR and Western blot, respectively. ROS and cytotoxicity were measured using flow cytometry and XTT assay, respectively. Results While chronic ART treatment increased CYP2E1 protein expression by 2-fold, ethanol and ethanol+ART increased CYP2E1 by ~5-fold. In contrast, ART and ethanol treatments decreased CYP3A4 protein expression by 38±17% and 74±15%, respectively, and the combination additively decreased CYP3A4 level by 90±8%. Expressions of superoxide dismutase (SOD1) and peroxiredoxin (PRDX6) were decreased by both ethanol and ART, however, the expressions of SOD2 and catalase were unaltered. These results suggested increased ethanol metabolism, increased ART accumulation, and decreased defense against ROS. Therefore, we determined the effects of ethanol and ART on ROS and cytotoxicity. While ART showed a slight increase, ethanol and ethanol+ART displayed significant increase in ROS and cytotoxicity. Moreover, the combination showed additive effects on ROS and cytotoxicity. Conclusions These results suggest that chronic ethanol, in the absence and presence of ART, increases ROS and cytotoxicity in monocytes, perhaps via CYPs and AOEs mediated pathways. This study has clinical implications in HIV+ alcohol users who are on ART. PMID:26727525

MDR1 and BCRP Transporter-Mediated Drug-Drug Interaction between Rilpivirine and Abacavir and Effect on Intestinal Absorption.

PubMed

Reznicek, Josef; Ceckova, Martina; Ptackova, Zuzana; Martinec, Ondrej; Tupova, Lenka; Cerveny, Lukas; Staud, Frantisek

2017-09-01

Rilpivirine (TMC278) is a highly potent nonnucleoside reverse transcriptase inhibitor (NNRTI) representing an effective component of combination antiretroviral therapy (cART) in the treatment of HIV-positive patients. Many antiretroviral drugs commonly used in cART are substrates of ATP-binding cassette (ABC) and/or solute carrier (SLC) drug transporters and, therefore, are prone to pharmacokinetic drug-drug interactions (DDIs). The aim of our study was to evaluate rilpivirine interactions with abacavir and lamivudine on selected ABC and SLC transporters in vitro and assess its importance for pharmacokinetics in vivo Using accumulation assays in MDCK cells overexpressing selected ABC or SLC drug transporters, we revealed rilpivirine as a potent inhibitor of MDR1 and BCRP, but not MRP2, OCT1, OCT2, or MATE1. Subsequent transport experiments across monolayers of MDCKII-MDR1, MDCKII-BCRP, and Caco-2 cells demonstrated that rilpivirine inhibits MDR1- and BCRP-mediated efflux of abacavir and increases its transmembrane transport. In vivo experiments in male Wistar rats confirmed inhibition of MDR1/BCRP in the small intestine, leading to a significant increase in oral bioavailability of abacavir. In conclusion, rilpivirine inhibits MDR1 and BCRP transporters and may affect pharmacokinetic behavior of concomitantly administered substrates of these transporters, such as abacavir. Copyright © 2017 American Society for Microbiology.

SDI Software Technology Program Plan Version 1.5

DTIC Science & Technology

1987-06-01

computer generation of auditory communication of meaningful speech. Most speech synthesizers are based on mathematical models of the human vocal tract, but...oral/ auditory and multimodal communications. Although such state-of-the-art interaction technology has not fully matured, user experience has...superior I pattern matching capabilities and the subliminal intuitive deduction capability. The error performance of humans can be helped by careful

Appropriating Video Surveillance for Art and Environmental Awareness: Experiences from ARTiVIS.

PubMed

Mendes, Mónica; Ângelo, Pedro; Correia, Nuno; Nisi, Valentina

2018-06-01

Arts, Real-Time Video and Interactivity for Sustainability (ARTiVIS) is an ongoing collaborative research project investigating how real-time video, DIY surveillance technologies and sensor data can be used as a tool for environmental awareness, activism and artistic explorations. The project consists of a series of digital contexts for aesthetic contemplation of nature and civic engagement, aiming to foster awareness and empowerment of local populations through DIY surveillance. At the core of the ARTIVIS efforts are a series of interactive installations (namely B-Wind!, Hug@tree and Play with Fire), that make use of surveillance technologies and real-time video as raw material to promote environmental awareness through the emotion generated by real-time connections with nature. Throughout the project development, the surveillance concept has been shifting from the use of surveillance technology in a centralized platform, to the idea of veillance with distributed peer-to-peer networks that can be used for science and environmental monitoring. In this paper we present the history of the ARTiVIS project, related and inspiring work, describe ongoing research work and explore the present and future challenges of appropriating surveillance technology for artistic, educational and civic engagement purposes.

Development of an Innovative Interactive Virtual Classroom System for K-12 Education Using Google App Engine

ERIC Educational Resources Information Center

Mumba, Frackson; Zhu, Mengxia

2013-01-01

This paper presents a Simulation-based interactive Virtual ClassRoom web system (SVCR: www.vclasie.com) powered by the state-of-the-art cloud computing technology from Google SVCR integrates popular free open-source math, science and engineering simulations and provides functions such as secure user access control and management of courses,…

Effects of Depression Alleviation on ART Adherence and HIV Clinic Attendance in Uganda, and the Mediating Roles of Self-Efficacy and Motivation

PubMed Central

Wagner, Glenn J.; Ghosh-Dastidar, Bonnie; Robinson, Eric; Ngo, Victoria K.; Glick, Peter; Mukasa, Barbara; Musisi, Seggane; Akena, Dickens

2016-01-01

With depression known to impede HIV care adherence and retention, we examined whether depression alleviation improves these disease management behaviors. A sample of 1028 depressed HIV clients in Uganda enrolled in a cluster randomized controlled trial of two depression care models, and were surveyed over 12 months. Serial regression analyses examined whether depression alleviation was associated with self-reported antiretroviral therapy (ART) adherence and clinic attendance at month 12, and whether these relationships were mediated by self-efficacy and motivation. Among those with major depression, depression alleviation was associated with better ART adherence and clinic attendance at month 12; these relationships were fully mediated by self-efficacy at month 12, while adherence motivation partially mediated the relationship between depression alleviation and ART adherence. When both mediators were entered simultaneously, only self-efficacy was a significant predictor and still fully mediated the relationship between depression alleviation and adherence. These findings suggest that depression alleviation benefits both ART adherence and clinic attendance, in large part through improved confidence and motivation to engage in these disease management behaviors. PMID:27438460

Effects of Depression Alleviation on ART Adherence and HIV Clinic Attendance in Uganda, and the Mediating Roles of Self-Efficacy and Motivation.

PubMed

Wagner, Glenn J; Ghosh-Dastidar, Bonnie; Robinson, Eric; Ngo, Victoria K; Glick, Peter; Mukasa, Barbara; Musisi, Seggane; Akena, Dickens

2017-06-01

With depression known to impede HIV care adherence and retention, we examined whether depression alleviation improves these disease management behaviors. A sample of 1028 depressed HIV clients in Uganda enrolled in a cluster randomized controlled trial of two depression care models, and were surveyed over 12 months. Serial regression analyses examined whether depression alleviation was associated with self-reported antiretroviral therapy (ART) adherence and clinic attendance at month 12, and whether these relationships were mediated by self-efficacy and motivation. Among those with major depression, depression alleviation was associated with better ART adherence and clinic attendance at month 12; these relationships were fully mediated by self-efficacy at month 12, while adherence motivation partially mediated the relationship between depression alleviation and ART adherence. When both mediators were entered simultaneously, only self-efficacy was a significant predictor and still fully mediated the relationship between depression alleviation and adherence. These findings suggest that depression alleviation benefits both ART adherence and clinic attendance, in large part through improved confidence and motivation to engage in these disease management behaviors.

CROI 2018: Advances in Antiretroviral Therapy.

PubMed

Tieu, Hong-Van; Taylor, Barbara S; Jones, Joyce; Wilkin, Timothy J

2018-05-01

The 2018 Conference on Retroviruses and Opportunistic Infections (CROI) showcased exciting data on new investigational agents including MK-8591 and tri-specific antibody targeting 3 highly conserved epitopes on HIV-1 in a single antibody. Clinical trials of initial antiretroviral therapy (ART) and switch studies involving bictegravir/emtricitabine/tenofovir alafenamide were presented. Intensification of initial ART with integrase strand transfer inhibitors did not increase the risk of immune reconstitution inflammatory syndrome. Pharmacokinetic issues were discussed, including the substantial drug-drug interactions between efavirenz-based ART and hormonal contraception delivered via a vaginal ring. Studies on pre-ART drug resistance and emergence of drug resistance after initial and second-line ART in different settings and populations were highlighted. Novel technologies to identify drug resistance included a free, cloud-based web service for HIV genotyping analysis and a promising technology for point-of-care drug resistance mutations testing. New strategies to improve the HIV care continuum included home-based testing with initiation of same-day ART and stratified care with specialized clinics to serve those disengaged in care, but the data on financial incentives were not encouraging. Several studies provided insights into the impact of early ART on decreasing the size of the HIV reservoir in HIV-infected infants. Pertinent conference findings relating to women's health issues included similar clinical outcomes between breastfeeding and formula feeding HIV-infected women, the problem of viral rebound and ART nonadherence in pregnancy and postpartum.

Mechanistic Indicators of Childhood Asthma (MICA) Study

EPA Science Inventory

The Mechanistic Indicators of Childhood Asthma (MICA) Study has been designed to incorporate state-of-the-art technologies to examine the physiological and environmental factors that interact to increase the risk of asthmatic responses. MICA is primarily a clinically-bases obser...

Instructional Technology. Symposium 18. [Concurrent Symposium Session at AHRD Annual Conference, 2000.

ERIC Educational Resources Information Center

2000

Three presentations are provided from Symposium 18, Instructional Technology, of the Academy of Human Resource Development (HRD) 2000 Conference Proceedings. "Strategies for Facilitating Interaction When Using Technology-Mediated Training Methods [TMTM]" (Jeffrey S. Lewis, Gary D. Geroy, Orlando Griego) focuses on differences between…

Accessibility of Electronically Mediated Education: Policy Issues

ERIC Educational Resources Information Center

Blair, Martin E.; Goldmann, Hilary; Relton, Joy

2004-01-01

Electronic technology has transformed education systems over the past 30 years. Generally speaking, technology has been an incredible benefit for individuals with disabilities. However, the use of technology, particularly in education, has been sometimes discriminatory toward those who are unable to interact with it in the standard ways…

DNA Methylation in Embryo Development: Epigenetic Impact of ART (Assisted Reproductive Technologies).

PubMed

Canovas, Sebastian; Ross, Pablo J; Kelsey, Gavin; Coy, Pilar

2017-11-01

DNA methylation can be considered a component of epigenetic memory with a critical role during embryo development, and which undergoes dramatic reprogramming after fertilization. Though it has been a focus of research for many years, the reprogramming mechanism is still not fully understood. Recent results suggest that absence of maintenance at DNA replication is a major factor, and that there is an unexpected role for TET3-mediated oxidation of 5mC to 5hmC in guarding against de novo methylation. Base-resolution and genome-wide profiling methods are enabling more comprehensive assessments of the extent to which ART might impair DNA methylation reprogramming, and which sequence elements are most vulnerable. Indeed, as we also review here, studies showing the effect of culture media, ovarian stimulation or embryo transfer on the methylation pattern of embryos emphasize the need to face ART-associated defects and search for strategies to mitigate adverse effects on the health of ART-derived children. © 2017 WILEY Periodicals, Inc.

Depressive symptoms, lifestyle structure, and ART adherence among HIV-infected individuals: a longitudinal mediation analysis.

PubMed

Magidson, Jessica F; Blashill, Aaron J; Safren, Steven A; Wagner, Glenn J

2015-01-01

Despite the well-documented relationship between depression and antiretroviral therapy (ART) nonadherence, few studies have identified explanatory pathways through which depression affects adherence. The current study tested lifestyle structure-the degree of organization and routinization of daily activities-as a mediator of this relationship, given previous evidence of lifestyle structure being associated with both depression and ART nonadherence. HIV-infected individuals starting or re-starting ART in the California Collaborative Treatment Group 578 study (n = 199) were assessed over 48 weeks. Adherence was measured using electronic monitoring caps to determine dose timing and doses taken, and viral load was assessed. The mediating role of lifestyle structure was tested using generalized linear mixed-effects modeling and bootstrapping. Lifestyle significantly mediated the relationship between depression and both measures of ART adherence behavior. Interventions that minimize disruptions to lifestyle structure and link adherence to daily activities may be useful for individuals with depression and ART nonadherence.

Heat meets light on the nanoscale

DOE PAGES

Boriskina, Svetlana V.; Tong, Jonathan K.; Hsu, Wei -Chun; ...

2016-06-11

We discuss the state-of-the-art and remaining challenges in the fundamental understanding and technology development for controlling light-matter interactions in nanophotonic environments in and away from thermal equilibrium. Furthermore, the topics covered range from the basics of the thermodynamics of light emission and absorption to applications in solar thermal energy generation, thermophotovoltaics, optical refrigeration, personalized cooling technologies, development of coherent incandescent light sources, and spinoptics.

Coupling two spin qubits with a high-impedance resonator

NASA Astrophysics Data System (ADS)

Harvey, S. P.; Bøttcher, C. G. L.; Orona, L. A.; Bartlett, S. D.; Doherty, A. C.; Yacoby, A.

2018-06-01

Fast, high-fidelity single and two-qubit gates are essential to building a viable quantum information processor, but achieving both in the same system has proved challenging for spin qubits. We propose and analyze an approach to perform a long-distance two-qubit controlled phase (CPHASE) gate between two singlet-triplet qubits using an electromagnetic resonator to mediate their interaction. The qubits couple longitudinally to the resonator, and by driving the qubits near the resonator's frequency, they can be made to acquire a state-dependent geometric phase that leads to a CPHASE gate independent of the initial state of the resonator. Using high impedance resonators enables gate times of order 10 ns while maintaining long coherence times. Simulations show average gate fidelities of over 96% using currently achievable experimental parameters and over 99% using state-of-the-art resonator technology. After optimizing the gate fidelity in terms of parameters tuneable in situ, we find it takes a simple power-law form in terms of the resonator's impedance and quality and the qubits' noise bath.

Tool-Mediated Authentic Learning in an Educational Technology Course: A Designed-Based Innovation

ERIC Educational Resources Information Center

Amory, Alan

2014-01-01

This design-based research project is concerned with the design, development and deployment of interactive technological learning environments to support contemporary education. The use of technologies in education often replicates instructivist positions and practices. However, the use of Cultural Historical Activity Theory (C), authentic…

A Learning Ecology Perspective: School Systems Sustaining Art Teaching with Technology

ERIC Educational Resources Information Center

Lin, Ching-Chiu

2011-01-01

Infusing technology into art education practice has been a continuous endeavor for preservice and in-service art teacher education. In recent years, art educators around the world have researched issues related to the preparation of art teacher technology competencies, including art teacher perceptions of working with technology, implementations…

Why does interactional justice promote organizational loyalty, job performance, and prevent mental impairment? The role of social support and social stressors.

PubMed

Otto, Kathleen; Mamatoglu, Nihal

2015-01-01

Using social exchange theory as a conceptual framework, we investigated the relationship between interactional justice and the outcomes organizational loyalty (affective commitment, turnover intentions), perceived job performance (self-rated performance, personal accomplishment), and mental impairment (cognitive irritation, emotional exhaustion) in an online survey of 218 employees working in the field of computer technology. Specifically, we predicted that interactional justice would heighten the quality of social exchange relationships and therefore expected perceived social support (POS) and bullying to mediate the proposed relationships. We tested our hypotheses applying a latent structural equation model. Our findings revealed that POS mediated the relationship between interactional justice and organizational loyalty, whereas bullying mediated the relationship between interactional justice and mental impairment. Practical implications are discussed concerning how to foster interactional justice and POS and how to weaken bullying behavior.

A structural equation model of patient-healthcare provider relationships and HIV-infected patient outcomes in Chinese populations.

PubMed

Chen, Wei-Ti; Shiu, Chengshi; Yang, Joyce P; Chuang, Peing; Zhang, Lin; Bao, Meijuan; Lu, Hongzhou

2018-03-01

Obtaining maximum antiretroviral therapy (ART) adherence is critical for maintaining a high CD4 count and strong immune function in PLWHA. Key factors for achieving optimum adherence include good medication self-efficacy, decreased medication-taking difficulties, and positive patient-healthcare provider (HCP) relationships. Limited studies have analyzed the correlation of these factors and ART adherence in Chinese population. In this paper, structural equation modeling was performed to assess the proposed model of relations between patient-HCP relationships and adherence. Audio Computer-Assisted Self-Interview (ACASI) software was used to collect data on ART adherence and patient variables among 227 PLWHA in Shanghai and Taipei. Participants completed a one-time 60-minute ACASI survey that consisted of standardized measures to assess demographics, recent CD4 counts, self-efficacy, patient-HCP relationship, adherence, and medication-taking difficulties. The data shown the relationship between patient-HCP relationships and adherence was significantly consistent with mediation by medication self-efficacy. However, patient-HCP interaction did not directly influence medication-taking difficulties, and medication-taking difficulties did not significantly affect CD4 counts. Furthermore, patient-HCP interactions did not directly impact CD4 counts; rather, the relation was consistent with mediation (by either better medication self-efficacy or better adherence) or by improved adherence alone. Future interventions should be designed to enhance self-management and provide better patient-HCP communication. This improved communication will enhance medication self-efficacy and decrease medication-taking difficulties. This in turn will improve medication adherence and immune function among PLWHA.

The Construction of Knowledge through Social Interaction via Computer-Mediated Communication

ERIC Educational Resources Information Center

Saritas, Tuncay

2008-01-01

With the advance in information and communication technologies, computer-mediated communication--more specifically computer conferencing systems (CCS)--has captured the interest of educators as an ideal tool to create a learning environment featuring active, participative, and reflective learning. Educators are increasingly adapting the features…

Development of a body motion interactive system with a weight voting mechanism and computer vision technology

NASA Astrophysics Data System (ADS)

Lin, Chern-Sheng; Chen, Chia-Tse; Shei, Hung-Jung; Lay, Yun-Long; Chiu, Chuang-Chien

2012-09-01

This study develops a body motion interactive system with computer vision technology. This application combines interactive games, art performing, and exercise training system. Multiple image processing and computer vision technologies are used in this study. The system can calculate the characteristics of an object color, and then perform color segmentation. When there is a wrong action judgment, the system will avoid the error with a weight voting mechanism, which can set the condition score and weight value for the action judgment, and choose the best action judgment from the weight voting mechanism. Finally, this study estimated the reliability of the system in order to make improvements. The results showed that, this method has good effect on accuracy and stability during operations of the human-machine interface of the sports training system.

Giant vacuum forces via transmission lines

PubMed Central

Shahmoon, Ephraim; Mazets, Igor; Kurizki, Gershon

2014-01-01

Quantum electromagnetic fluctuations induce forces between neutral particles, known as the van der Waals and Casimir interactions. These fundamental forces, mediated by virtual photons from the vacuum, play an important role in basic physics and chemistry and in emerging technologies involving, e.g., microelectromechanical systems or quantum information processing. Here we show that these interactions can be enhanced by many orders of magnitude upon changing the character of the mediating vacuum modes. By considering two polarizable particles in the vicinity of any standard electric transmission line, along which photons can propagate in one dimension, we find a much stronger and longer-range interaction than in free space. This enhancement may have profound implications on many-particle and bulk systems and impact the quantum technologies mentioned above. The predicted giant vacuum force is estimated to be measurable in a coplanar waveguide line. PMID:25002503

Love in the Time of Facebook: How Technology Now Shapes Romantic Attachments in College Students

ERIC Educational Resources Information Center

Klein, Michael C.

2013-01-01

College counseling clinicians need to understand how students use technology to form, sustain, and end romantic attachments. Students now frequently incorporate aspects of these technologically based interactions, or mediated communications, into counseling sessions and often make important attributions based on them. Heavy daily use of a growing…

Challenges in Transcribing Multimodal Data: A Case Study

ERIC Educational Resources Information Center

Helm, Francesca; Dooly, Melinda

2017-01-01

Computer-mediated communication (CMC) once meant principally text-based communication mediated by computers, but rapid technological advances in recent years have heralded an era of multimodal communication with a growing emphasis on audio and video synchronous interaction. As CMC, in all its variants (text chats, video chats, forums, blogs, SMS,…

Task-Induced Development of Hinting Behaviors in Online Task-Oriented L2 Interaction

ERIC Educational Resources Information Center

Balaman, Ufuk

2018-01-01

Technology-mediated task settings are rich interactional domains in which second language (L2) learners manage a multitude of interactional resources for task accomplishment. The affordances of these settings have been repeatedly addressed in computer-assisted language learning (CALL) literature mainly based on theory-informed task design…

Authoring and Enactment of Mobile Pyramid-Based Collaborative Learning Activities

ERIC Educational Resources Information Center

Manathunga, Kalpani; Hernández-Leo, Davinia

2018-01-01

Collaborative learning flow patterns (CLFPs) formulate best practices for the orchestration of activity sequences and collaboration mechanisms that can elicit fruitful social interactions. Mobile technology features offer opportunities to support interaction mediation and content accessibility. However, existing mobile collaborative learning…

Digital Literacy and Netiquette: Awareness and Perception in EFL Learning Context

ERIC Educational Resources Information Center

Nia, Sara Farshad; Marandi, Susan

2014-01-01

With the growing popularity of digital technologies and computer-mediated communication (CMC), various types of interactive communication technology are being increasingly integrated into foreign/second language learning environments. Nevertheless, due to its nature, online communication is susceptible to misunderstandings and miscommunications,…

Race-Based Medical Mistrust, Medication Beliefs and HIV Treatment Adherence: Test of a Mediation Model in People Living with HIV/AIDS

PubMed Central

Kalichman, Seth C.; Eaton, Lisa; Kalichman, Moira O.; Grebler, Tama; Merely, Cynthia; Welles, Brandi

2016-01-01

Race-based medical mistrust significantly predicts non-adherence to antiretroviral therapy (ART) in people living with HIV. The current study builds on previous research that shows beliefs about medication necessity (i.e., “My medicines protect me from becoming worse”) and concerns (i.e., Having to take my medicines worries me) mediate the association between race-based medical mistrust and medication adherence. Racial and ethnic minority men and women living with HIV and receiving ART (N=178) in a southern US city completed computerized measures of demographic and health characteristics, telephone interviews of race-based medical mistrust and medication beliefs, and unannounced phone-based pill counts for ART adherence. Multiple mediation modeling showed that medical mistrust is related to medication necessity and concerns beliefs and ART adherence. Furthermore, medication necessity beliefs predicted ART adherence. The indirect effect of medical mistrust on adherence through medication necessity beliefs was also significant. Results confirm that medication necessity beliefs, although not concerns beliefs, mediate the association between medical mistrust and ART adherence. Medication necessity beliefs offer a viable target for interventions to improve ART adherence in the context of mistrust that patients may have for medical providers and health care systems. PMID:27392477

Alternatives in Medical Education: Non-Animal Methods.

ERIC Educational Resources Information Center

Carlson, Peggy, Ed.

The technology explosion in medical education has led to the use of computer models, videotapes, interactive videos, and state-of-the-art simulators in medical training. This booklet describes alternatives to using animals in medical education. Although it is mainly intended to describe products applicable to medical school courses, high-quality,…

Innovative Orientation Leads to Improved Success in Online Courses

ERIC Educational Resources Information Center

Taylor, Jean M.; Dunn, Margie; Winn, Sandra K.

2015-01-01

A team of instructional designers, educators, and the School of Liberal Arts (SLA) academic program coordinator from a nonprofit online college, collaborated on producing short voice-over videos with interactive elements that address the most common technology frustrations of beginning students. These videos were inserted into the "Start…

Ecological Education: Integration of Scientific Knowledge and Figurative Representations.

ERIC Educational Resources Information Center

Senkevich, V. M.

1991-01-01

Argues that understanding the interaction of society and the environment is a social-economical, technological, and moral task. Describes techniques developed by one Soviet academy's ecological education laboratory for helping middle school students integrate knowledge from science and art. Suggests that the study of specific ecological problems…

Designing Effective Multimedia Kiosks.

ERIC Educational Resources Information Center

Liu, Min; Wheat, John

Interactive kiosks are becoming very popular in industries, educational institutions and public facilities. This paper discusses the design and development of a multimedia kiosk (Project iTOWER) by the University of Texas at Austin using the state-of-the-art technology and reports the results of the use of this system by students. The kiosk…

Teaching Photography: An Interdisciplinary Theme for Science, Technology, and Art.

ERIC Educational Resources Information Center

Stamovlasis, Dimitrios

This paper addresses contemporary concerns with the disintegration of meaning and fragmentation of knowledge. It appeals to interdisciplinary curricula, where an effort is made to reveal the interactive relationships among different fields of knowledge. The paper proposes Photography as an interdisciplinary theme, which involves Chemistry,…

Louise Rosenblatt Seeks QtAznBoi@aol.com for LTR: Using Chat Rooms in Interdisciplinary Middle School Classrooms.

ERIC Educational Resources Information Center

Albright, James; Purohit, Kiran; Walsh, Christopher

2002-01-01

Discusses online student-teacher interactions and notes how these encounters forced educators to think about the use of computer-mediated technologies. Reflects on both overly optimistic stances toward technology and stances that position the students as aliens and cyborgs. Examines the dynamic relationship that emerges as technologies, students,…

Art: The Telling of History through Technology.

ERIC Educational Resources Information Center

Scali, Nancy

1990-01-01

Describes several writing projects that use computers to expose students to art, cultural history, and present day technology. Suggests activities for Prehistoric art, Egyptian art, African art, Japanese art, and Native American art. (MG)

The potential of cellular technology to mediate social networks for support of chronic disease self-management.

PubMed

Roblin, Douglas W

2011-01-01

Productive interactions among patients, friends/family, and health care providers, as outlined by the Chronic Care Model, are important for promoting adherence to recommended care and good health outcomes among adults with a chronic illness. Characteristics of these interactions--active participation, collaboration, and data sharing among constituents--are the same as those of social networks organized around Web 2.0 principles and technology. Thus, the Web 2.0 framework can be used to configure social networks without the inherent spatiotemporal constraints of face-to-face interactions that remain prevalent in health care delivery. In this article, the author outlines various design principles and decisions for a pilot study in which cellular technology was used to mediate interactions between adults with Type 2 diabetes and supporters (i.e., family members or friends selected by the patients who agree provide support) to motivate regular self-monitoring of blood glucose (among the diabetes participants). Participants generally found the network to be relatively easy to use. Some diabetes patients reported improved attention to self-monitoring; and, patient-selected supporters indicated improvements in emotional and instrumental support that should benefit diabetes patients' lifestyle and health.

High Penetration Photovoltaic Power Electronics and Energy Management Technology Research, Development and Demonstration: Cooperative Research and Development Final Report, CRADA Number CRD-13-517

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hudgins, Andrew P.

Advanced Energy Industries, Inc., will partner with DOE's National Renewable Energy Laboratory (NREL) to conduct research and development to demonstrate technologies that will increase the penetration of photovoltaic (PV) technologies for commercial and utility applications. Standard PV power control systems use simple control techniques that only provide real power to the grid. A focus of this partnership is to demonstrate how state of the art control and power electronic technologies can be combined to create a utility interactive control platform.

Bluetooth as a Playful Public Art Interface

NASA Astrophysics Data System (ADS)

Stukoff, Maria N.

This chapter investigates how the application of emergent communication technologies assisted in the design of playful art experience in a public place. Every Passing Moment (EPM), was a mobile public artwork that tracked and recorded any discoverable Bluetooth device to automatically seed a flower in a virtual garden projected onto an urban screen. The EPM was the first public art work to run blu_box, a custom-designed Bluetooth system for mobile telephony. The aim of blu_box was to build a system that supported playful interactions between the public and an urban screen, openly accessible to anyone with a Bluetooth-enabled mobile phone. This participatory engagement was observed in EPM on three levels, namely; unconscious, conscious, and dynamic play. Furthermore, this chapter highlights how sound and face-to-face communication proved imperative in the play dynamics of EPM. In conclusion, this chapter proposes ways in which the use of emergent communication technologies in public places, especially when interfaced with urban screening platforms, can construct playful city spaces for the public at large.

Silk-Based Biomaterials for Sustained Drug Delivery

PubMed Central

Yucel, Tuna; Lovett, Michael L.; Kaplan, David L.

2014-01-01

Silk presents a rare combination of desirable properties for sustained drug delivery, including aqueous-based purification and processing options without chemical cross-linkers, compatibility with common sterilization methods, controllable and surface-mediated biodegradation into non-inflammatory by-products, biocompatibility, utility in drug stabilization, and robust mechanical properties. A versatile silk-based toolkit is currently available for sustained drug delivery formulations of small molecule through macromolecular drugs, with a promise to mitigate several drawbacks associated with other degradable sustained delivery technologies in the market. Silk-based formulations utilize silk’s well-defined nano- through microscale structural hierarchy, stimuli-responsive self-assembly pathways and crystal polymorphism, as well as sequence and genetic modification options towards targeted pharmaceutical outcomes. Furthermore, by manipulating the interactions between silk and drug molecules, near-zero order sustained release may be achieved through diffusion- and degradation-based release mechanisms. Because of these desirable properties, there has been increasing industrial interest in silk-based drug delivery systems currently at various stages of the developmental pipeline from pre-clinical to FDA-approved products. Here, we discuss the unique aspects of silk technology as a sustained drug delivery platform and highlight the current state of the art in silk-based drug delivery. We also offer a potential early development pathway for silk-based sustained delivery products. PMID:24910193

Depression longitudinally mediates the association of appearance concerns to ART non-adherence in HIV-infected individuals with a history of injection drug use.

PubMed

Blashill, Aaron J; Gordon, Janna R; Safren, Steven A

2014-02-01

Appearance concerns are common among HIV-infected individuals, and previous cross-sectional and longitudinal data indicate that these concerns are associated with antiretroviral therapy (ART) non-adherence. However, to date, no known prospective data have explored the mechanism behind this relationship. Thus, the aim of the current study was to test depression severity as a prospective mediator of the relationship between appearance concerns and ART non-adherence in HIV-infected individuals with a history of injection drug use (IDU). Participants were 89 HIV-infected individuals with a history of IDU who participated in a prospective, randomized controlled trial of cognitive behavioral therapy for depression and medication adherence. Clinician-administered measures of depression severity and appearance concerns, along with electronic monitoring of ART non-adherence were included. Data were analyzed using longitudinal linear mixed-level modeling, and mediation was tested via the Monte Carlo Method of Assessing Mediation. Appearance concerns were predictive of depression severity, γ = .31, SE = .076, 95 % CI [.16, .46], t = 4.1, p = .0001, and depression severity was predictive of ART non-adherence, γ = 3.3, SE = 1.3, 95 % CI [.8, 5.8], t = 2.6, p = .01. The effect of appearance concerns on ART non-adherence, however, was significantly mediated by depression severity, γ = 1.02, 95 % CI [.21, 2.1]. Appearance concerns are associated with depression severity, which in turn is associated with ART non-adherence. Integrative interventions addressing appearance concerns, depression and ART adherence are needed, as this is one potential pathway towards worse health outcomes in HIV-infected individuals.

Implementing Artificial Intelligence Behaviors in a Virtual World

NASA Technical Reports Server (NTRS)

Krisler, Brian; Thome, Michael

2012-01-01

In this paper, we will present a look at the current state of the art in human-computer interface technologies, including intelligent interactive agents, natural speech interaction and gestural based interfaces. We describe our use of these technologies to implement a cost effective, immersive experience on a public region in Second Life. We provision our Artificial Agents as a German Shepherd Dog avatar with an external rules engine controlling the behavior and movement. To interact with the avatar, we implemented a natural language and gesture system allowing the human avatars to use speech and physical gestures rather than interacting via a keyboard and mouse. The result is a system that allows multiple humans to interact naturally with AI avatars by playing games such as fetch with a flying disk and even practicing obedience exercises using voice and gesture, a natural seeming day in the park.

Comprehensive evaluation of contemporary assisted reproduction technology laboratory operations to determine staffing levels that promote patient safety and quality care.

PubMed

Alikani, Mina; Go, Kathryn J; McCaffrey, Caroline; McCulloh, David H

2014-11-01

To consider how staffing requirements have changed with evolving and increasingly more complex assisted reproduction technology (ART) laboratory practice. Analysis by four laboratory directors from three different ART programs of the level of complexity and time requirements for contemporary ART laboratory activities to determine adequate staffing levels. University-based and private ART programs. None. None. Human resource requirements for ART procedures. Both complexity and time required for completion of a contemporary ART cycle have increased significantly compared with the same requirements for the "traditional cycle" of the past. The latter required roughly 9 personnel hours, but a contemporary cycle can require up to 20 hours for completion. Consistent with this increase, a quantitative analysis shows that the number of embryologists required for safe and efficient operation of the ART laboratory has also increased. This number depends on not only the volume but also the types of procedures performed: the higher the number of complex procedures, the more personnel required. An interactive Personnel Calculator is introduced that can help determine staffing needs. The increased complexity of the contemporary ART laboratory requires a new look at the allocation of human resources. Our work provides laboratory directors with a practical, individualized tool to determine their staffing requirements with a view to increasing the safety and efficiency of operations. The work could serve as the basis for revision of the 2008 American Society for Reproductive Medicine (ASRM) staffing guidelines. Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

A Research-Informed, School-Based Professional Development Workshop Programme to Promote Dialogic Teaching with Interactive Technologies

ERIC Educational Resources Information Center

Hennessy, Sara; Dragovic, Tatjana; Warwick, Paul

2018-01-01

The study reported in this article investigated the influence of a research-informed, school-based, professional development workshop programme on the quality of classroom dialogue using the interactive whiteboard (IWB). The programme aimed to develop a dialogic approach to teaching and learning mediated through more interactive uses of the IWB,…

The measurement of childbearing motivation in couples considering the use of assisted reproductive technology.

PubMed

Miller, Warren B; Millstein, Susan G; Pasta, David J

2008-01-01

Relatively little is known about the motivational antecedents to the use of assisted reproductive technology (ART). In this paper we measure the fertility motivations of infertile couples who are considering the use of ART, using an established instrument, the Childbearing Questionnaire (CBQ). Our sample consists of 214 men and 216 women who were interviewed at home after an initial screening for ART but before making a final decision. We conducted two sets of analyses with the obtained data. In one set, we compared the scores on scales and subscales of the CBQ for the males and females in our sample with the scores for males and females from a comparable normative sample. For these analyses we first examined sample and gender differences with a four-group analysis of variance. We then conducted a series of linear models that included background characteristics as covariates and interactions between sample, gender, and age and between those three variables and the background characteristics. The results showed the expected higher positive and lower negative motivations in the ART sample and a significant effect on positive motivations of the interaction between sample and age. In the second set of analyses, we developed several new subscales relevant to facets of the desire for a child that appear to be important in ART decision-making. These facets include the desire to be genetically related to the child and the desire to experience pregnancy and childbirth. A third facet, the desire for parenthood, is already well covered by the existing subscales. The results showed the new subscales to have satisfactory reliability and validity. The results also showed that the original and new subscales predicted the three facets of the desire for a child in a multivariate context. We conclude with a general discussion of the way our findings relate both to ART decision-making and to further research on the motivations that drive it.

Access Denied? Twenty-First-Century Technology in Schools

ERIC Educational Resources Information Center

Male, Trevor; Burden, Kevin

2014-01-01

This article considers how developments in technologies have transformed the kind of social interaction possible over the Internet, making it feasible to undertake discourse and dialogue without having to rely solely on text-based mediation. This represents a fundamental change to learning, shifting from passive acquisition of someone else's ideas…

Endogenous voltage gradients as mediators of cell-cell communication: strategies for investigating bioelectrical signals during pattern formation

PubMed Central

Adams, Dany S.; Levin, Michael

2013-01-01

Alongside the well-known chemical modes of cell-cell communication, we find an important and powerful system of bioelectrical signaling: changes in the resting voltage potential (Vmem) of the plasma membrane driven by ion channels, pumps and gap junctions. Slow Vmem changes in all cells serve as a highly conserved, information-bearing pathway that regulates cell proliferation, migration and differentiation. In embryonic and regenerative pattern formation and in the disorganization of neoplasia, bioelectrical cues serve as mediators of large-scale anatomical polarity, organ identity and positional information. Recent developments have resulted in tools that enable a high-resolution analysis of these biophysical signals and their linkage with upstream and downstream canonical genetic pathways. Here, we provide an overview for the study of bioelectric signaling, focusing on state-of-the-art approaches that use molecular physiology and developmental genetics to probe the roles of bioelectric events functionally. We highlight the logic, strategies and well-developed technologies that any group of researchers can employ to identify and dissect ionic signaling components in their own work and thus to help crack the bioelectric code. The dissection of bioelectric events as instructive signals enabling the orchestration of cell behaviors into large-scale coherent patterning programs will enrich on-going work in diverse areas of biology, as biophysical factors become incorporated into our systems-level understanding of cell interactions. PMID:22350846

The cinema-cognition dialogue: a match made in brain.

PubMed

Dudai, Yadin

2012-01-01

That human evolution amalgamates biological and cultural change is taken as a given, and that the interaction of brain, body, and culture is more reciprocal then initially thought becomes apparent as the science of evolution evolves (Jablonka and Lamb, 2005). The contribution of science and technology to this evolutionary process is probably the first to come to mind. The biology of Homo sapiens permits and promotes the development of technologies and artefacts that enable us to sense and reach physical niches previously inaccessible. This extends our biological capabilities, but is also expected to create selective pressures on these capabilities. The jury is yet out on the pace at which critical biological changes take place in evolution. There is no question, however, that the kinetics of technological and cultural change is much faster, rendering the latter particularly important in the biography of the individual and the species alike. The capacity of art to enrich human capabilities is recurrently discussed by philosophers and critics (e.g., Arsitotle/Poetics, Richards, 1925; Smith and Parks, 1951; Gibbs, 1994). Yet less attention is commonly allotted to the role of the arts in the aforementioned ongoing evolutional tango. My position is that the art of cinema is particularly suited to explore the intriguing dialogue between art and the brain. Further, in the following set of brief notes, intended mainly to trigger further thinking on the subject, I posit that cinema provides an unparalleled and highly rewarding experimentation space for the mind of the individual consumer of that art. In parallel, it also provides a useful and promising device for investigating brain and cognition.

The cinema-cognition dialogue: a match made in brain

PubMed Central

Dudai, Yadin

2012-01-01

That human evolution amalgamates biological and cultural change is taken as a given, and that the interaction of brain, body, and culture is more reciprocal then initially thought becomes apparent as the science of evolution evolves (Jablonka and Lamb, 2005). The contribution of science and technology to this evolutionary process is probably the first to come to mind. The biology of Homo sapiens permits and promotes the development of technologies and artefacts that enable us to sense and reach physical niches previously inaccessible. This extends our biological capabilities, but is also expected to create selective pressures on these capabilities. The jury is yet out on the pace at which critical biological changes take place in evolution. There is no question, however, that the kinetics of technological and cultural change is much faster, rendering the latter particularly important in the biography of the individual and the species alike. The capacity of art to enrich human capabilities is recurrently discussed by philosophers and critics (e.g., Arsitotle/Poetics, Richards, 1925; Smith and Parks, 1951; Gibbs, 1994). Yet less attention is commonly allotted to the role of the arts in the aforementioned ongoing evolutional tango. My position is that the art of cinema is particularly suited to explore the intriguing dialogue between art and the brain. Further, in the following set of brief notes, intended mainly to trigger further thinking on the subject, I posit that cinema provides an unparalleled and highly rewarding experimentation space for the mind of the individual consumer of that art. In parallel, it also provides a useful and promising device for investigating brain and cognition. PMID:22969715

Using Gaming Equipment to Teach

ERIC Educational Resources Information Center

Curriculum Review, 2009

2009-01-01

Gaming equipment (such as Nintendo's Wii[TM]) is making its way to schools and classrooms. However, most of the discussion regarding how to use this technology and integrate it into lesson plans is happening in blogs on the Internet. An advocate of interactive media in the classroom, Dr. Dawn Hawkins, a faculty member for the Art Institute of…

Polish Teenage Students' Willingness to Engage in On-Line Intercultural Interactions

ERIC Educational Resources Information Center

Wach, Aleksandra

2013-01-01

Computer-based technologies, including various forms of computer-mediated communication (CMC), provide L2 users with opportunities to engage in intercultural interactions which may promote the development of their intercultural communicative competence. The article reports the findings of a study that investigated how beyond-the-classroom…

Mapping Languaging in Digital Spaces: Literacy Practices at Borderlands

ERIC Educational Resources Information Center

Dahlberg, Giulia Messina; Bagga-Gupta, Sangeeta

2016-01-01

The study presented in this article explores the ways in which discursive-technologies shape interaction in "digitally-mediated" educational settings in terms of affordances and constraints for the participants. Our multi-scale sociocultural-dialogical analysis of the interactional order in the online sessions of an "Italian for…

Interfering and Resolving: How Tabletop Interaction Facilitates Co-Construction of Argumentative Knowledge

ERIC Educational Resources Information Center

Falcao, Taciana Pontual; Price, Sara

2011-01-01

Tangible technologies and shared interfaces create new paradigms for mediating collaboration through dynamic, synchronous environments, where action is as important as speech for participating and contributing to the activity. However, interaction with shared interfaces has been shown to be inherently susceptible to peer interference, potentially…

Viewing Chinese art on an interactive tabletop.

PubMed

Hsieh, Chun-ko; Hung, Yi-Ping; Ben-Ezra, Moshe; Hsieh, Hsin-Fang

2013-01-01

To protect fragile paintings and calligraphy, Taiwan's National Palace Museum (NPM) has policies controlling the frequency and duration of their exposure. So, visitors might not see the works they planned to see. To address this problem, the NPM installed an interactive tabletop for viewing the works. This tabletop, the first to feature multiresolution and gigapixel photography technology, displays extremely high-quality images revealing brushwork-level detail. A user study at the NPM examined the tabletop's performance and collected visitor feedback.

SIG -- The Role of Human-Computer Interaction in Next-Generation Control Rooms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ronald L. Boring; Jacques Hugo; Christian Richard

2005-04-01

The purpose of this CHI Special Interest Group (SIG) is to facilitate the convergence between human-computer interaction (HCI) and control room design. HCI researchers and practitioners actively need to infuse state-of-the-art interface technology into control rooms to meet usability, safety, and regulatory requirements. This SIG outlines potential HCI contributions to instrumentation and control (I&C) and automation in control rooms as well as to general control room design.

Enhanced Chiral Discriminatory van der Waals Interactions Mediated by Chiral Surfaces

NASA Astrophysics Data System (ADS)

Barcellona, Pablo; Safari, Hassan; Salam, A.; Buhmann, Stefan Yoshi

2017-05-01

We predict a discriminatory interaction between a chiral molecule and an achiral molecule which is mediated by a chiral body. To achieve this, we generalize the van der Waals interaction potential between two ground-state molecules with electric, magnetic, and chiral response to nontrivial environments. The force is evaluated using second-order perturbation theory with an effective Hamiltonian. Chiral media enhance or reduce the free interaction via many-body interactions, making it possible to measure the chiral contributions to the van der Waals force with current technology. The van der Waals interaction is discriminatory with respect to enantiomers of different handedness and could be used to separate enantiomers. We also suggest a specific geometric configuration where the electric contribution to the van der Waals interaction is zero, making the chiral component the dominant effect.

A Technological, Pedagogical, Arts Knowledge Framework

ERIC Educational Resources Information Center

Jensen, Amy Petersen

2016-01-01

This article invites media arts and technology educators to find synergies in their classroom curriculum and practice. Encouraging the use of the National Media Arts Standards it summons teachers to develop a useful framework for technological practice that utilizes arts knowledge and pedagogies.

New Technologies, New Possibilities for the Arts and Multimodality in English Language Arts

ERIC Educational Resources Information Center

Williams, Wendy R.

2014-01-01

This article discusses the arts, multimodality, and new technologies in English language arts. It then turns to the example of the illuminated text--a multimodal book report consisting of animated text, music, and images--to consider how art, multimodality, and technology can work together to support students' reading of literature and inspire…

Nomad Biosensors: A New Multiplexed Technology for the Screening of GPCR Ligands.

PubMed

Mella, Rosa M; Kortazar, Danel; Roura-Ferrer, Meritxell; Salado, Clarisa; Valcárcel, María; Castilla, Amaia; Villacé, Patricia

2018-06-01

Nomad Technology (Innoprot [Innovative Technologies in Biological Systems], Derio, Spain), a novel tool for multiplexing high-throughput cell-based G protein-coupled receptor (GPCR) assays, is described in this work. This new technology comprises a family of fluorescent biosensors called Nomad Biosensors that allow for the measurement of responses mediated by G proteins through their interactions with second-messenger transduction proteins. GPCRs are one of the largest protein families of receptors in eukaryotes, and their signaling mediates important physiological processes within cells. Thus, GPCRs are associated with a wide variety of diseases, and considered major targets in therapeutic research. Nomad constitutes a novel tool for unraveling the mechanism of GPCR signal transduction by simultaneously tracing different pathways. GPCR activation changes the structural folding of the biosensor and promotes its vesicularization, as well as an increase in the fluorescence intensity. Based on this technology, the MPX Nomad cellular model was developed to discriminate between the Ca 2+ -mediated pathway and the cyclic adenosine monophosphate (cAMP)-mediated pathway. To validate this model, endothelin receptor B (ET B R) was coexpressed into the MPX Nomad cell line and assessed with a specific agonist, an antagonist, and a chemical library of compounds. Nomad Technology optimizes the identification of novel GPCR ligands and enables the testing of large numbers of compounds.

Contemporary Technology.

ERIC Educational Resources Information Center

Clark, Gilbert, Ed.

1999-01-01

This theme issue of "InSEA News" focuses on contemporary technology and art education. The articles are: "International Travel and Contemporary Technology" (Gilbert Clark); "Recollections and Visions for Electronic Computing in Art Education" (Guy Hubbard); "Using Technologies in Art Education: A Review of…

Real-time 3D human capture system for mixed-reality art and entertainment.

PubMed

Nguyen, Ta Huynh Duy; Qui, Tran Cong Thien; Xu, Ke; Cheok, Adrian David; Teo, Sze Lee; Zhou, ZhiYing; Mallawaarachchi, Asitha; Lee, Shang Ping; Liu, Wei; Teo, Hui Siang; Thang, Le Nam; Li, Yu; Kato, Hirokazu

2005-01-01

A real-time system for capturing humans in 3D and placing them into a mixed reality environment is presented in this paper. The subject is captured by nine cameras surrounding her. Looking through a head-mounted-display with a camera in front pointing at a marker, the user can see the 3D image of this subject overlaid onto a mixed reality scene. The 3D images of the subject viewed from this viewpoint are constructed using a robust and fast shape-from-silhouette algorithm. The paper also presents several techniques to produce good quality and speed up the whole system. The frame rate of our system is around 25 fps using only standard Intel processor-based personal computers. Besides a remote live 3D conferencing and collaborating system, we also describe an application of the system in art and entertainment, named Magic Land, which is a mixed reality environment where captured avatars of human and 3D computer generated virtual animations can form an interactive story and play with each other. This system demonstrates many technologies in human computer interaction: mixed reality, tangible interaction, and 3D communication. The result of the user study not only emphasizes the benefits, but also addresses some issues of these technologies.

Technology-mediated information sharing between patients and clinicians in primary care encounters.

PubMed

Asan, Onur; Montague, Enid

The aim of this study was to identify and describe the use of electronic health records for information sharing between patients and clinicians in primary care encounters. This topic is particularly important as computers and other technologies are increasingly implemented in multi-user health care settings where interactions and communication between patients and clinicians are integral to interpersonal and organizational outcomes. An ethnographic approach was used to classify the encounters into distinct technology-use patterns based on clinicians` interactions with the technology and patients. Each technology-use pattern was quantitatively analysed to assist with comparison. Quantitative analysis was based on duration of patient and clinician gaze at EHR. Physicians employed three different styles to share information using EHRs: Active information-sharing, in which a clinician turns the monitor towards the patient and uses the computer to actively share information with the patient;Passive information-sharing, when a clinician does not move the monitor, but the patient might see the monitor by leaning in if they choose; andTechnology withdrawal, when a clinician does not share the monitor with the patient. A variety of technology-mediated information-sharing styles may be effective in providing patient-centred care. New EHR designs may be needed to facilitate information sharing between patients and clinicians.

Interactive Technologies for Teacher Training: Comparing Performance and Assessment in Second Life and simSchool

ERIC Educational Resources Information Center

Meritt, Julia; Gibson, David; Christensen, Rhonda; Knezek, Gerald

2013-01-01

Two alternative technologies forming the basis of computer-mediated teacher preparation systems are compared and contrasted regarding implementation, operation, and assessment considerations. The role-playing system in Second Life is shown to have the unique characteristic of developing a co-constructed pedagogical identity, while the flight…

Fostering Students' Participation in Online Environments: Focus on Interaction, Communication and Problem Solving

ERIC Educational Resources Information Center

Zacharis, Nick Z.

2009-01-01

Rapid technological advances in the areas of telecommunications, computer technology and the Internet have made available to tutors and learners in the domain of online learning, a broad array of tools that provide the possibility to facilitate and enhance learning to higher levels of critical reflective thinking. Computer mediated communication…

Digital Technology in Teaching International Business: Is a Tradeoff between Richness and Reach Required?

ERIC Educational Resources Information Center

Wymbs, Cliff; Kijne, Hugo

2003-01-01

This analysis extends the traditional marketing tradeoffs between richness (depth of knowledge) and reach (geographic area coverage) to the emerging technology-mediated education industry, and then specifically evaluates their effect on the teaching of international business. It asserts that interactive learning, particularly as it applies to team…

Interaction between rhinitis and asthma: state of the art.

PubMed

Frieri, Marianne

2003-01-01

Rhinitis and asthma are very prevalent allergic disorders with comorbid features, similar risk factors, and environmental triggers. Pathophysiological processes are linked via tissue histopathology, immunologic pathway, and inflammatory mediators. Allergen challenge of the upper airway can increase lower-airway responsiveness and allergen challenge of the lower airway can lead to upper-airway inflammation. Both allergic rhinitis and asthma exert a high social and economic burden in significant loss of work and school days as well as impairment for children and adults.

Graphic Arts Technology: Industrial Arts Curriculum Guide. Grades 9-12. Bulletin No. 1334 (Tentative).

ERIC Educational Resources Information Center

Louisiana State Dept. of Education, Baton Rouge.

The tentative guide in graphic arts technology for senior high schools is part of a series of industrial arts curriculum materials developed by the State of Louisiana. The course is designed to provide "hands-on" experience with tools and materials along with a study of the industrial processes in graphic arts technology. In addition,…

Art and Technology: Computers in the Studio?

ERIC Educational Resources Information Center

Ruby-Baird, Janet

1997-01-01

Because the graphic industry demands graduates with computer skills, art students want college programs that include complex computer technologies. However, students can produce good computer art only if they have mastered traditional drawing and design skills. Discusses designing an art curriculum including both technology and traditional course…

Art and Technology.

ERIC Educational Resources Information Center

Lamal, Pauline Dove

Art has always adapted technological advances to its own uses. In the last 15 years, art has turned to color photocopiers, computers, mimeograph machines, and thermofax copiers. With this in mind, Central Piedmont Community College began offering a course in 1982 called "Art and Technology" which focused on the application of office…

Promoter Targeting RNAs: Unexpected Contributors to the Control of HIV-1 Transcription.

PubMed

Suzuki, Kazuo; Ahlenstiel, Chantelle; Marks, Katherine; Kelleher, Anthony D

2015-01-27

In spite of prolonged and intensive treatment with combined antiretroviral therapy (cART), which efficiently suppresses plasma viremia, the integrated provirus of HIV-1 persists in resting memory CD4(+) T cells as latent infection. Treatment with cART does not substantially reduce the burden of latent infection. Once cART is ceased, HIV-1 replication recrudesces from these reservoirs in the overwhelming majority of patients. There is increasing evidence supporting a role for noncoding RNAs (ncRNA), including microRNAs (miRNAs), antisense (as)RNAs, and short interfering (si)RNA in the regulation of HIV-1 transcription. This appears to be mediated by interaction with the HIV-1 promoter region. Viral miRNAs have the potential to act as positive or negative regulators of HIV transcription. Moreover, inhibition of virally encoded long-asRNA can induce positive transcriptional regulation, while antisense strands of siRNA targeting the NF-κB region suppress viral transcription. An in-depth understanding of the interaction between ncRNAs and the HIV-1 U3 promoter region may lead to new approaches for the control of HIV reservoirs. This review focuses on promoter associated ncRNAs, with particular emphasis on their role in determining whether HIV-1 establishes active or latent infection.

Promoter Targeting RNAs: Unexpected Contributors to the Control of HIV-1 Transcription

PubMed Central

Suzuki, Kazuo; Ahlenstiel, Chantelle; Marks, Katherine; Kelleher, Anthony D

2015-01-01

In spite of prolonged and intensive treatment with combined antiretroviral therapy (cART), which efficiently suppresses plasma viremia, the integrated provirus of HIV-1 persists in resting memory CD4+ T cells as latent infection. Treatment with cART does not substantially reduce the burden of latent infection. Once cART is ceased, HIV-1 replication recrudesces from these reservoirs in the overwhelming majority of patients. There is increasing evidence supporting a role for noncoding RNAs (ncRNA), including microRNAs (miRNAs), antisense (as)RNAs, and short interfering (si)RNA in the regulation of HIV-1 transcription. This appears to be mediated by interaction with the HIV-1 promoter region. Viral miRNAs have the potential to act as positive or negative regulators of HIV transcription. Moreover, inhibition of virally encoded long-asRNA can induce positive transcriptional regulation, while antisense strands of siRNA targeting the NF-κB region suppress viral transcription. An in-depth understanding of the interaction between ncRNAs and the HIV-1 U3 promoter region may lead to new approaches for the control of HIV reservoirs. This review focuses on promoter associated ncRNAs, with particular emphasis on their role in determining whether HIV-1 establishes active or latent infection. PMID:25625613

A Conceptual Framework Based on Activity Theory for Mobile CSCL

ERIC Educational Resources Information Center

Zurita, Gustavo; Nussbaum, Miguel

2007-01-01

There is a need for collaborative group activities that promote student social interaction in the classroom. Handheld computers interconnected by a wireless network allow people who work on a common task to interact face to face while maintaining the mediation afforded by a technology-based system. Wirelessly interconnected handhelds open up new…

Research of Technical Knowledge and Creativity Development of Children in Pre-Primary Education through Interactive Whiteboard

ERIC Educational Resources Information Center

Brecka, Peter; Cervenanská, Marcela

2016-01-01

The introduced study represents methodology and results of research focused on utilization of interactive whiteboard as didactic technology mediating information through multimedia worksheets applied in education process in pre-primary education. Its aim was to determine whether it can significantly increase the level of children's acquired…

Development of L2 Interactional Resources for Online Collaborative Task Accomplishment

ERIC Educational Resources Information Center

Balaman, Ufuk; Sert, Olcay

2017-01-01

Technology-mediated task environments have long been considered integral parts of L2 learning and teaching processes. However, the interactional resources that the learners deploy to complete tasks in these environments have remained largely unexplored due to an overall focus on task design and outcomes rather than task engagement processes. With…

Blogging through the Music Student Teaching Experience: Developing Virtual Communities of Practice

ERIC Educational Resources Information Center

Fitzpatrick, Kate R.

2014-01-01

Within educational settings, well-developed web-based social networking technologies such as interactive weblogs (blogs) can serve to effectively facilitate and mediate interactions among members of a "community of practice" (Chong, 2008; Wenger, White, & Smith, 2009). The purpose of this study was to investigate the use of an…

Interactivity in a Web Conference Training Context: Effects on Trainers and Trainees

ERIC Educational Resources Information Center

Stephens, Keri K.; Mottet, Timothy P.

2008-01-01

Organizations continue to use technology to train and share information. This study focused specifically on how trainers and trainees interact in the mediated Web conference training context. Using the rhetorical and relational goal theory of instructional communication, this 2x2 experimental study tested the effects of trainer-controlled and…

Infertility Fact Sheet

MedlinePlus

... Couples with unexplained infertility What is assisted reproductive technology (ART)? Assisted reproductive technology (ART) is a group ... the woman's body. How often is assisted reproductive technology (ART) successful? Success rates vary and depend on ...

Learning the determinants of satisfaction and usage intention of instant messaging.

PubMed

Lin, Chieh-Peng; Huang, Hsiu-Nien; Joe, Sheng-Wuu; Ma, Hwa-Chun

2008-06-01

This study proposes a model for evaluating usage intention toward interactive information technology. The test results reveal that usage intention is influenced directly by satisfaction, perceived ease of use, perceived personalization, and perceived social interaction, while being also influenced indirectly by perceived reliability, perceived instantaneity, perceived ease of use, perceived social image, and perceived social interaction via the mediation of satisfaction.

DJINNI: A Novel Technology Supported Exposure Therapy Paradigm for SAD Combining Virtual Reality and Augmented Reality.

PubMed

Ben-Moussa, Maher; Rubo, Marius; Debracque, Coralie; Lange, Wolf-Gero

2017-01-01

The present paper explores the benefits and the capabilities of various emerging state-of-the-art interactive 3D and Internet of Things technologies and investigates how these technologies can be exploited to develop a more effective technology supported exposure therapy solution for social anxiety disorder. "DJINNI" is a conceptual design of an in vivo augmented reality (AR) exposure therapy mobile support system that exploits several capturing technologies and integrates the patient's state and situation by vision-based, audio-based, and physiology-based analysis as well as by indoor/outdoor localization techniques. DJINNI also comprises an innovative virtual reality exposure therapy system that is adaptive and customizable to the demands of the in vivo experience and therapeutic progress. DJINNI follows a gamification approach where rewards and achievements are utilized to motivate the patient to progress in her/his treatment. The current paper reviews the state of the art of technologies needed for such a solution and recommends how these technologies could be integrated in the development of an individually tailored and yet feasible and effective AR/virtual reality-based exposure therapy. Finally, the paper outlines how DJINNI could be part of classical cognitive behavioral treatment and how to validate such a setup.

DJINNI: A Novel Technology Supported Exposure Therapy Paradigm for SAD Combining Virtual Reality and Augmented Reality

PubMed Central

Ben-Moussa, Maher; Rubo, Marius; Debracque, Coralie; Lange, Wolf-Gero

2017-01-01

The present paper explores the benefits and the capabilities of various emerging state-of-the-art interactive 3D and Internet of Things technologies and investigates how these technologies can be exploited to develop a more effective technology supported exposure therapy solution for social anxiety disorder. “DJINNI” is a conceptual design of an in vivo augmented reality (AR) exposure therapy mobile support system that exploits several capturing technologies and integrates the patient’s state and situation by vision-based, audio-based, and physiology-based analysis as well as by indoor/outdoor localization techniques. DJINNI also comprises an innovative virtual reality exposure therapy system that is adaptive and customizable to the demands of the in vivo experience and therapeutic progress. DJINNI follows a gamification approach where rewards and achievements are utilized to motivate the patient to progress in her/his treatment. The current paper reviews the state of the art of technologies needed for such a solution and recommends how these technologies could be integrated in the development of an individually tailored and yet feasible and effective AR/virtual reality-based exposure therapy. Finally, the paper outlines how DJINNI could be part of classical cognitive behavioral treatment and how to validate such a setup. PMID:28503155

Remaking Poems: Combining Translation and Digital Media to Interest High School Students in Poetry Analysis

ERIC Educational Resources Information Center

Simpson, Amy Beth

2017-01-01

In American high schools, the practice of poetry analysis as a study of language art has declined. Outworn methods have contributed to the trend away from close interactions with the text, to the unfortunate end that millennial high school students neither understand nor enjoy poetry. Digital technology coupled with principles of translation…

EduSpeak[R]: A Speech Recognition and Pronunciation Scoring Toolkit for Computer-Aided Language Learning Applications

ERIC Educational Resources Information Center

Franco, Horacio; Bratt, Harry; Rossier, Romain; Rao Gadde, Venkata; Shriberg, Elizabeth; Abrash, Victor; Precoda, Kristin

2010-01-01

SRI International's EduSpeak[R] system is a software development toolkit that enables developers of interactive language education software to use state-of-the-art speech recognition and pronunciation scoring technology. Automatic pronunciation scoring allows the computer to provide feedback on the overall quality of pronunciation and to point to…

Responding to the Call: Arts Methodologies Informing 21st Century Literacies

ERIC Educational Resources Information Center

Huber, Adrienne; Dinham, Judith; Chalk, Beryl

2015-01-01

With the advent of digital technologies, a new adventure began. How the world works has changed, and we cannot go back. Digitally savvy children born in the digital age (i.e., DigiKids) are interacting with and responding to rich, curatable multimodal communications as part of their daily-lived experience. For DigiKids, traditional text-based…

The Social Semantic Web in Intelligent Learning Environments: State of the Art and Future Challenges

ERIC Educational Resources Information Center

Jovanovic, Jelena; Gasevic, Dragan; Torniai, Carlo; Bateman, Scott; Hatala, Marek

2009-01-01

Today's technology-enhanced learning practices cater to students and teachers who use many different learning tools and environments and are used to a paradigm of interaction derived from open, ubiquitous, and socially oriented services. In this context, a crucial issue for education systems in general, and for Intelligent Learning Environments…

Assisted Reproductive Technology (ART)

MedlinePlus

... Share Facebook Twitter Pinterest Email Print Assisted Reproductive Technology (ART) ART refers to treatments and procedures that ... American Society for Reproductive Medicine. (2015). Assisted reproductive technologies: A guide for patients . Retrieved May 31, 2016, ...

Association between Perceived Discrimination in Healthcare Settings and HIV Medication Adherence: Mediating Psychosocial Mechanisms.

PubMed

Turan, Bulent; Rogers, Anna Joy; Rice, Whitney S; Atkins, Ghislaine C; Cohen, Mardge H; Wilson, Tracey E; Adimora, Adaora A; Merenstein, Daniel; Adedimeji, Adebola; Wentz, Eryka L; Ofotokun, Igho; Metsch, Lisa; Tien, Phyllis C; Johnson, Mallory O; Turan, Janet M; Weiser, Sheri D

2017-12-01

There is insufficient research on the impact of perceived discrimination in healthcare settings on adherence to antiretroviral therapy (ART), particularly among women living with HIV, and even less is known about psychosocial mechanisms that may mediate this association. Cross-sectional analyses were conducted in a sample of 1356 diverse women living with HIV enrolled in the Women's Interagency HIV Study (WIHS), a multi-center cohort study. Indirect effects analysis with bootstrapping was used to examine the potential mediating roles of internalized stigma and depressive symptoms in the association between perceived discrimination in healthcare settings and ART adherence. Perceived discrimination in healthcare settings was negatively associated with optimal (95% or better) ART adherence (adjusted odds ratio (AOR) = 0.81, p = 0.02, 95% confidence interval (CI) [0.68, 0.97]). Furthermore, internalization of stigma and depressive symptoms mediated the perceived discrimination-adherence association: Serial mediation analyses revealed a significant indirect effect of perceived discrimination in healthcare settings on ART adherence, first through internalized HIV stigma, and then through depressive symptoms (B = - 0.08, SE = 0.02, 95% CI [- 0.12, - 0.04]). Perceiving discrimination in healthcare settings may contribute to internalization of HIV-related stigma, which in turn may lead to depressive symptoms, with downstream adverse effects on ART adherence among women. These findings can guide the design of interventions to reduce discrimination in healthcare settings, as well as interventions targeting psychosocial mechanisms that may impact the ability of women living with HIV to adhere to ART regimens.

Preparing for Assisted Reproductive Technology

MedlinePlus

... CDC Cancel Submit Search The CDC Assisted Reproductive Technology (ART) Note: Javascript is disabled or is not ... visit this page: About CDC.gov . Assisted Reproductive Technology (ART) What Is ART Patient Resources Preparing for ...

Graphical User Interface in Art

NASA Astrophysics Data System (ADS)

Gwilt, Ian

This essay discusses the use of the Graphical User Interface (GUI) as a site of creative practice. By creatively repositioning the GUI as a work of art it is possible to challenge our understanding and expectations of the conventional computer interface wherein the icons and navigational architecture of the GUI no longer function as a technological tool. These artistic recontextualizations are often used to question our engagement with technology and to highlight the pivotal place that the domestic computer has taken in our everyday social, cultural and (increasingly), creative domains. Through these works the media specificity of the screen-based GUI can broken by dramatic changes in scale, form and configuration. This can be seen through the work of new media artists who have re-imagined the GUI in a number of creative forms both, within the digital, as image, animation, net and interactive art, and in the analogue, as print, painting, sculpture, installation and performative event. Furthermore as a creative work, the GUI can also be utilized as a visual way-finder to explore the relationship between the dynamic potentials of the digital and the concretized qualities of the material artifact.

Emergence, Agency, and Interaction-Notes from the Field.

PubMed

Penny, Simon

2015-01-01

This article describes the development of several interactive installations and robotic artworks developed through the 1990s and the technological, theoretical, and discursive context in which those works arose. The main works discussed are Petit Mal (1989-1995), Sympathetic Sentience (1996-1997), Fugitive I (1996-1997), Traces (1998-1999), and Fugitive II (2001-2004)-full documentation at ( www.simonpenny.net/works ). These works were motivated by a critical analysis of cognitivist computer science, which contrasted with notions of embodied experience arising from the arts. The works address questions of agency and interaction, informed by cybernetics and artificial life.

Soundscapes/Artabilitation - Evolution of a Hybrid Human Performance Concept, Method & Apparatus Where Digital Interactive Media, The Arts, & Entertainment are Combined

NASA Astrophysics Data System (ADS)

Brooks, A. L.

'SoundScapes' is a body of empirical research that for almost two decades has focused upon investigating noninvasive gesture control of multi-sensory stimuli and potential uses in therapy and the arts. In this context noninvasive gesture refers to motion in invisible activity zones of a system input device utilizing technology outside of human vision. Especially targeted are disabled people of all ages, and special focus has been on the profoundly impaired who especially have limited opportunities for creative self-articulation and playful interaction. The concept has been explored in various situations including: - live stage performances; interactive room installations for museums, workshops, and festivals; and in health-care sessions at hospitals, institutes and special schools. Multifaceted aspects continuously cross-inform in a systemic manner, and each situation where the motion-sensitive environment is applied is considered as a hybrid system. Whilst simplistic in concept, i.e. learning by playful and creative doings, inherent are complexities of optimizing the interactive system to user-experience and evaluation of same. This chapter presents the system in context to its conceived-for-target community; it also presents the parallel practice-led investigations in performance art. Reciprocal design and reflective cross-analysis of the activities has resulted such that performance informs design and strategies of intervention and evaluation with impaired users, and vice versa.

Bodily Explorations in Space: Social Experience of a Multimodal Art Installation

NASA Astrophysics Data System (ADS)

Jacucci, Giulio; Spagnolli, Anna; Chalambalakis, Alessandro; Morrison, Ann; Liikkanen, Lassi; Roveda, Stefano; Bertoncini, Massimo

We contribute with an extensive field study of a public interactive art installation that applies multimodal interface technologies. The installation is part of a Theater production on Galileo Galilei and includes: projected galaxies that are generated and move according to motion of visitors changing colour depending on their voices; projected stars that configure themselves around shadows of visitors. In the study we employ emotion scales (PANAS), qualitative analysis of questionnaire answers and video-recordings. PANAS rates indicate dominantly positive feelings, further described in the subjective verbalizations as gravitating around interest, ludic pleasure and transport. Through the video analysis, we identified three phases in the interaction with the artwork (circumspection, testing, play) and two pervasive features of these phases (experience sharing and imitation), which were also found in the verbalizations. Both video and verbalisations suggest that visitor’s experience and ludic pleasure are rooted in the embodied, performative interaction with the installation, and is negotiated with the other visitors.

The artist emerges: visual art learning alters neural structure and function.

PubMed

Schlegel, Alexander; Alexander, Prescott; Fogelson, Sergey V; Li, Xueting; Lu, Zhengang; Kohler, Peter J; Riley, Enrico; Tse, Peter U; Meng, Ming

2015-01-15

How does the brain mediate visual artistic creativity? Here we studied behavioral and neural changes in drawing and painting students compared to students who did not study art. We investigated three aspects of cognition vital to many visual artists: creative cognition, perception, and perception-to-action. We found that the art students became more creative via the reorganization of prefrontal white matter but did not find any significant changes in perceptual ability or related neural activity in the art students relative to the control group. Moreover, the art students improved in their ability to sketch human figures from observation, and multivariate patterns of cortical and cerebellar activity evoked by this drawing task became increasingly separable between art and non-art students. Our findings suggest that the emergence of visual artistic skills is supported by plasticity in neural pathways that enable creative cognition and mediate perceptuomotor integration. Copyright © 2014 Elsevier Inc. All rights reserved.

Technology Education in the Liberal Arts.

ERIC Educational Resources Information Center

Wiens, A. Emerson

1987-01-01

Reviews development of technological literacy in liberal arts curriculum, especially efforts of Sloan Foundation. Observes that few general education courses with technology content are taught by industrial educators; focus of the new liberal arts is on understanding how technology works; quantitative skills are vital; and social and human…

Preface: Special Topic on Ions in Water.

PubMed

Allen, Heather C; Tobias, Douglas J

2018-06-14

This special topic contains a diverse collection of 40 articles that span the vast range of subjects that fall under the heading "Ions in Water," a longstanding mainstay of chemical physics. The investigations reported herein employ state-of-the-art theoretical, computational, and experimental techniques, as well as combinations thereof, to provide new insights into the fundamental aspects of ion solvation and the important roles that ions play in mediating physicochemical processes occurring in solutions and at interfaces in a wide variety of settings relevant to biological, environmental, and technological applications.

Nanoparticle-mediated hyperthermia in cancer therapy

PubMed Central

Chatterjee, Dev Kumar; Diagaradjane, Parmeswaran; Krishnan, Sunil

2011-01-01

A small rise in tumor temperature (hyperthermia) makes cancer cells more susceptible to radiation and chemotherapy. The means of achieving this is not trivial, and traditional methods have certain drawbacks. Loading tumors with systematically asministered energy-transducing nanoparticles can circumvent several of the obstacles to achieve tumor hyperthermia. However, nanoparticles also face unique challenges prior to clinical implementation. This article summarizes the state-of-the-art current technology and discusses the advantages and challenges of the three major nanoparticle formulations in focus: gold nanoshells and nanorods, superparamagnetic iron oxide particles and carbon nanotubes. PMID:22506095

Preface: Special Topic on Ions in Water

NASA Astrophysics Data System (ADS)

Allen, Heather C.; Tobias, Douglas J.

2018-06-01

This special topic contains a diverse collection of 40 articles that span the vast range of subjects that fall under the heading "Ions in Water," a longstanding mainstay of chemical physics. The investigations reported herein employ state-of-the-art theoretical, computational, and experimental techniques, as well as combinations thereof, to provide new insights into the fundamental aspects of ion solvation and the important roles that ions play in mediating physicochemical processes occurring in solutions and at interfaces in a wide variety of settings relevant to biological, environmental, and technological applications.

CMC Technologies for Teaching Foreign Languages: What's on the Horizon?

ERIC Educational Resources Information Center

Lafford, Peter A.; Lafford, Barbara A.

2005-01-01

Computer-mediated communication (CMC) technologies have begun to play an increasingly important role in the teaching of foreign/second (L2) languages. Its use in this context is supported by a growing body of CMC research that highlights the importance of the negotiation of meaning and computer-based interaction in the process of second language…

Art-Science-Technology collaboration through immersive, interactive 3D visualization

NASA Astrophysics Data System (ADS)

Kellogg, L. H.

2014-12-01

At the W. M. Keck Center for Active Visualization in Earth Sciences (KeckCAVES), a group of geoscientists and computer scientists collaborate to develop and use of interactive, immersive, 3D visualization technology to view, manipulate, and interpret data for scientific research. The visual impact of immersion in a CAVE environment can be extremely compelling, and from the outset KeckCAVES scientists have collaborated with artists to bring this technology to creative works, including theater and dance performance, installations, and gamification. The first full-fledged collaboration designed and produced a performance called "Collapse: Suddenly falling down", choreographed by Della Davidson, which investigated the human and cultural response to natural and man-made disasters. Scientific data (lidar scans of disaster sites, such as landslides and mine collapses) were fully integrated into the performance by the Sideshow Physical Theatre. This presentation will discuss both the technological and creative characteristics of, and lessons learned from the collaboration. Many parallels between the artistic and scientific process emerged. We observed that both artists and scientists set out to investigate a topic, solve a problem, or answer a question. Refining that question or problem is an essential part of both the creative and scientific workflow. Both artists and scientists seek understanding (in this case understanding of natural disasters). Differences also emerged; the group noted that the scientists sought clarity (including but not limited to quantitative measurements) as a means to understanding, while the artists embraced ambiguity, also as a means to understanding. Subsequent art-science-technology collaborations have responded to evolving technology for visualization and include gamification as a means to explore data, and use of augmented reality for informal learning in museum settings.

How food insecurity contributes to poor HIV health outcomes: Qualitative evidence from the San Francisco Bay Area.

PubMed

Whittle, Henry J; Palar, Kartika; Seligman, Hilary K; Napoles, Tessa; Frongillo, Edward A; Weiser, Sheri D

2016-12-01

Food-insecure people living with HIV/AIDS (PLHIV) consistently exhibit worse clinical outcomes than their food-secure counterparts. This relationship is mediated in part through non-adherence to antiretroviral therapy (ART), sub-optimal engagement in HIV care, and poor mental health. An in-depth understanding of how these pathways operate in resource-rich settings, however, remains elusive. We aimed to understand the relationship between food insecurity and HIV health among low-income individuals in the San Francisco Bay Area using qualitative methods. Semi-structured in-depth interviews were conducted with 34 low-income PLHIV receiving food assistance from a non-profit organization. Interviews explored experiences with food insecurity and its perceived effects on HIV-related health, mental health, and health behaviors including taking ART and attending clinics. Thematic content analysis of transcripts followed an integrative inductive-deductive approach. Food insecurity was reported to contribute to poor ART adherence and missing scheduled clinic visits through various mechanisms, including exacerbated ART side effects in the absence of food, physical feelings of hunger and fatigue, and HIV stigma at public free-meal sites. Food insecurity led to depressive symptoms among participants by producing physical feelings of hunger, aggravating pre-existing struggles with depression, and nurturing a chronic self-perception of social failure. Participants further explained how food insecurity, depression, and ART non-adherence could reinforce each other in complex interactions. Our study demonstrates how food insecurity detrimentally shapes HIV health behavior and outcomes through complex and interacting mechanisms, acting via multiple socio-ecological levels of influence in this setting. The findings emphasize the need for broad, multisectoral approaches to tackling food insecurity among urban poor PLHIV in the United States. Copyright © 2016 Elsevier Ltd. All rights reserved.

Technology Education in Taiwan: A Transition from Industrial Arts to Living Technology.

ERIC Educational Resources Information Center

Lee, Lung-Sheng Steven

Secondary-level technology education in Taiwan is shifting its emphasis from industrial arts to living technology in an effort to overcome the following problems: industrial arts is seen as a subordinate subject; the public's perceptions are not aligned with the field; and industrial technology teachers have had to struggle with huge class sizes…

Awareness in the Home: The Nuances of Relationships, Domestic Coordination and Communication

NASA Astrophysics Data System (ADS)

Greenberg, Saul; Neustaedter, Carman; Elliot, Kathryn

Computing has changed dramatically over the last decade. While some changes arose from technological advances, the most profound effects are in how technologies are used by everyday people for activities other than task-oriented work. Computers are now central to new ways of engaging in play, interpersonal and small group communication, community interaction, entertainment, personal creativity dissemination, personal publication, and so on. We are particularly interested in domestic computing, where technology mediates how families and other inhabitants interact within the context of the home. While domestic computing can incorporate many things, we focus in this chapter on the role awareness plays in domestic coordination and communication.

Technology Interventions to Manage Food Intake: Where Are We Now?

PubMed

Allman-Farinelli, Margaret; Gemming, Luke

2017-09-23

This review describes the state-of-the-art for dietary assessment using smartphone apps and digital technology and provides an update on the efficacy of technology-mediated interventions for dietary change. Technology has progressed from apps requiring entry of foods consumed, to digital imaging to provide food intake data. However, these methods rely on patients being active in data collection. The automated estimation of the volume and composition of every meal consumed globally is years away. The use of text messaging, apps, social media, and combinations of these for interventions is growing and proving effective for type 2 diabetes mellitus (T2DM). Effectiveness of text messaging for obesity management is improving and multicomponent interventions show promise. A stand-alone app is less likely to produce positive outcomes and social media is relatively unexplored. A concentrated effort will be needed to progress digital dietary assessment. Researcher-designed technology programs are producing positive outcomes for T2DM but further research is needed in the area of weight management.

Keeping up with Our Students: The Evolution of Technology and Standards in Art Education

ERIC Educational Resources Information Center

Patton, Ryan M.; Buffington, Melanie L.

2016-01-01

This article addresses the standards of technology in the visual arts, arguing the standards function as de facto policy, the guidelines that shape what teachers teach. In this study, we investigate how art education standards approach technology as a teaching tool and artmaking medium, analyzing the current National Visual Arts Standards, the…

Interactive Whiteboard Professional Development: A Look through the Eyes of Early Childhood Educators

ERIC Educational Resources Information Center

Evans, Nicole Southerland

2012-01-01

With vastly ever-changing technology, there come greater possibilities in the school classroom. One possibility includes the interactive whiteboard, IWB (Higgins, Beauchamp, & Miller, 2007). However, there is little research on how to effectively promote the use of an IWB in the classroom for anything other than as a mediating tool. One option…

What Factors Affect the Way Teams Interact in an On-Line Graduate Course?

ERIC Educational Resources Information Center

Ingram, K. W.; Conley, C.; McDonald, S.; Parker, V.; Rivers, J.

This study examined how adult graduate students made use of technology to mediate group interactions and processes in an online learning environment, also noting why individual groups of students chose particular tools and methods. The online course was delivered using a third-party course management tool. The structure of the course and the use…

Mandarin Students' Perceptions of Multimodal Interaction in a Web Conferencing Environment: A Satisfaction Survey

ERIC Educational Resources Information Center

Tseng, Jun-Jie

2015-01-01

A major indicator of whether online courses have been effective and successful is student satisfaction. Copious research points to lack of interaction as the most cited reason for student dissatisfaction. To improve this problem, new Computer-Mediated Communication (CMC) technology could be considered as an option to enhance the online learning…

Counseling Issues for Gay Men and Lesbians Seeking Assisted Reproductive Technologies (ART)

MedlinePlus

... with gay men and lesbians seeking assisted reproductive technology (ART) More lesbian, gay, bisexual, and transgender (LGBT) ... choosing to build a family through assisted reproductive technology (ART) have concerns about how to best nurture ...

"Jiselle and the Royal Jelly": Power, Conflict and Culture in an Interdisciplinary Game Design Course

ERIC Educational Resources Information Center

Dickey, Michele D.

2010-01-01

With the rising popularity of digital games, a growing number of universities are developing programmes in various areas of digital design and interactive media to meet the needs for game-related courses. Faculty of this emerging field are grappling with the complexity of developing curricula which integrate art, design and technology and of…

The Complexity of HIV Persistence and Pathogenesis in the Lung Under Antiretroviral Therapy: Challenges Beyond AIDS

PubMed Central

2014-01-01

Abstract Antiretroviral therapy (ART) represents a significant milestone in the battle against AIDS. However, we continue learning about HIV and confronting challenges 30 years after its discovery. HIV has cleverly tricked both the host immune system and ART. First, the many HIV subtypes and recombinant forms have different susceptibilities to antiretroviral drugs, which may represent an issue in countries where ART is just being introduced. Second, even under the suppressive pressures of ART, HIV still increases inflammatory mediators, deregulates apoptosis and proliferation, and induces oxidative stress in the host. Third, the preference of HIV for CXCR4 as a co-receptor may also have noxious outcomes, including potential malignancies. Furthermore, HIV still replicates cryptically in anatomical reservoirs, including the lung. HIV impairs bronchoalveolar T-lymphocyte and macrophage immune responses, rendering the lung susceptible to comorbidities. In addition, HIV-infected individuals are significantly more susceptible to long-term HIV-associated complications. This review focuses on chronic obstructive pulmonary disease (COPD), pulmonary arterial hypertension, and lung cancer. Almost two decades after the advent of highly active ART, we now know that HIV-infected individuals on ART live as long as the uninfected population. Fortunately, its availability is rapidly increasing in low- and middle-income countries. Nevertheless, ART is not risk-free: the developed world is facing issues with antiretroviral drug toxicity, resistance, and drug–drug interactions, while developing countries are confronting issues with immune reconstitution inflammatory syndrome. Several aspects of the complexity of HIV persistence and challenges with ART are discussed, as well as suggestions for new avenues of research. PMID:24797368

Media Arts: Arts Education for a Digital Age

ERIC Educational Resources Information Center

Peppler, Kylie A.

2010-01-01

Background/Context: New technologies have been largely absent in arts education curriculum even though they offer opportunities to address arts integration, equity, and the technological prerequisites of an increasingly digital age. This paper draws upon the emerging professional field of "media arts" and the ways in which youth use new…

The virtual environment display system

NASA Technical Reports Server (NTRS)

Mcgreevy, Michael W.

1991-01-01

Virtual environment technology is a display and control technology that can surround a person in an interactive computer generated or computer mediated virtual environment. It has evolved at NASA-Ames since 1984 to serve NASA's missions and goals. The exciting potential of this technology, sometimes called Virtual Reality, Artificial Reality, or Cyberspace, has been recognized recently by the popular media, industry, academia, and government organizations. Much research and development will be necessary to bring it to fruition.

Deus Ex Machina: Tradition, Technology, and the Chicanafuturist Art of Marion C. Martinez

ERIC Educational Resources Information Center

Ramirez, Catherine S.

2004-01-01

The visual art of Marion C. Martinez is examined. Through technology, Martinez reproduces and transforms traditional Indo-Hispanic art forms, at the same time, underscores New Mexico's history as a dumping ground for technological waste.

Knowledge-based systems in Japan

NASA Technical Reports Server (NTRS)

Feigenbaum, Edward; Engelmore, Robert S.; Friedland, Peter E.; Johnson, Bruce B.; Nii, H. Penny; Schorr, Herbert; Shrobe, Howard

1994-01-01

This report summarizes a study of the state-of-the-art in knowledge-based systems technology in Japan, organized by the Japanese Technology Evaluation Center (JTEC) under the sponsorship of the National Science Foundation and the Advanced Research Projects Agency. The panel visited 19 Japanese sites in March 1992. Based on these site visits plus other interactions with Japanese organizations, both before and after the site visits, the panel prepared a draft final report. JTEC sent the draft to the host organizations for their review. The final report was published in May 1993.

The Use of Weblog in Language Learning: Motivation of Second Language Learners in Reading Classroom

ERIC Educational Resources Information Center

Sulaiman, Ahmad Nasaruddin; Kassim, Asiah

2010-01-01

The age of technology has enabled learners to interact with other users outside the four walls of the classroom. Weblogs, in particular, provide a channel for asynchronous computer-mediated communication to take place in the learning process. Motivation is one of the learning aspects that is greatly enhanced by the use of technology.…

Art Historical Appropriation in a Visual Culture-Based Art Education

ERIC Educational Resources Information Center

Trafi-Prats, Laura

2009-01-01

Critical art histories have strategically contributed to the constitution of visual culture studies as an interdisciplinary field that interprets the mediations of mass-produced imagery in contemporary culture. This article advocates for an anti-historicist perspective of art historical knowledge connected to cultural analysis and centered on the…

Art as a Means of Accessing Ourselves. Using Art in Psychotherapy.

PubMed

d'Errico, Immacolata

2017-09-01

Using art in psychotherapy could become an interesting instrument for the cure and the prevention of psychological and psychiatric problems. This belongs to that trend that sees the mediation of art as having big potential to go beyond the spoken word. Everybody knows that our emotions, thoughts, feelings, and so on, are living in the body and speaking through the body, in fact the symbolic dimension (art, music, dance, painting and so on) reconfigures the experience of living. In this form of therapy we use Art as a means of accessing ourselves and opening ourselves up to the world. The forms of artistic mediation that we mainly describe in the paper are the basic elements of tango and performative theatrical technique (Theatre of the Oppressed and Physical Theatre). In the final part of this paper a series of images illustrate specific cases in which the method and its outcomes are described.

Combining Brain–Computer Interfaces and Assistive Technologies: State-of-the-Art and Challenges

PubMed Central

Millán, J. d. R.; Rupp, R.; Müller-Putz, G. R.; Murray-Smith, R.; Giugliemma, C.; Tangermann, M.; Vidaurre, C.; Cincotti, F.; Kübler, A.; Leeb, R.; Neuper, C.; Müller, K.-R.; Mattia, D.

2010-01-01

In recent years, new research has brought the field of electroencephalogram (EEG)-based brain–computer interfacing (BCI) out of its infancy and into a phase of relative maturity through many demonstrated prototypes such as brain-controlled wheelchairs, keyboards, and computer games. With this proof-of-concept phase in the past, the time is now ripe to focus on the development of practical BCI technologies that can be brought out of the lab and into real-world applications. In particular, we focus on the prospect of improving the lives of countless disabled individuals through a combination of BCI technology with existing assistive technologies (AT). In pursuit of more practical BCIs for use outside of the lab, in this paper, we identify four application areas where disabled individuals could greatly benefit from advancements in BCI technology, namely, “Communication and Control”, “Motor Substitution”, “Entertainment”, and “Motor Recovery”. We review the current state of the art and possible future developments, while discussing the main research issues in these four areas. In particular, we expect the most progress in the development of technologies such as hybrid BCI architectures, user–machine adaptation algorithms, the exploitation of users’ mental states for BCI reliability and confidence measures, the incorporation of principles in human–computer interaction (HCI) to improve BCI usability, and the development of novel BCI technology including better EEG devices. PMID:20877434

Scientists and artists: ""Hey! You got art in my science! You got science on my art

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elfman, Mary E; Hayes, Birchard P; Michel, Kelly D

The pairing of science and art has proven to be a powerful combination since the Renaissance. The combination of these two seemingly disparate disciplines ensured that even complex scientific theories could be explored and effectively communicated to both the subject matter expert and the layman. In modern times, science and art have frequently been considered disjoint, with objectives, philosophies, and perspectives often in direct opposition to each other. However, given the technological advances in computer science and high fidelity 3-D graphics development tools, this marriage of art and science is once again logically complimentary. Art, in the form of computermore » graphics and animation created on supercomputers, has already proven to be a powerful tool for improving scientific research and providing insight into nuclear phenomena. This paper discusses the power of pairing artists with scientists and engineers in order to pursue the possibilities of a widely accessible lightweight, interactive approach. We will use a discussion of photo-realism versus stylization to illuminate the expected beneficial outcome of such collaborations and the societal advantages gained by a non-traditional pa11nering of these two fields.« less

Germ line genome editing in clinics: the approaches, objectives and global society

PubMed Central

2017-01-01

Genome editing allows for the versatile genetic modification of somatic cells, germ cells and embryos. In particular, CRISPR/Cas9 is worldwide used in biomedical research. Although the first report on Cas9-mediated gene modification in human embryos focused on the prevention of a genetic disease in offspring, it raised profound ethical and social concerns over the safety of subsequent generations and the potential misuse of genome editing for human enhancement. The present article considers germ line genome editing approaches from various clinical and ethical viewpoints and explores its objectives. The risks and benefits of the following three likely objectives are assessed: the prevention of monogenic diseases, personalized assisted reproductive technology (ART) and genetic enhancement. Although genetic enhancement should be avoided, the international regulatory landscape suggests the inevitability of this misuse at ART centers. Under these circumstances, possible regulatory responses and the potential roles of public dialogue are discussed. PMID:26615180

Human-Computer Interaction, Tourism and Cultural Heritage

NASA Astrophysics Data System (ADS)

Cipolla Ficarra, Francisco V.

We present a state of the art of the human-computer interaction aimed at tourism and cultural heritage in some cities of the European Mediterranean. In the work an analysis is made of the main problems deriving from training understood as business and which can derail the continuous growth of the HCI, the new technologies and tourism industry. Through a semiotic and epistemological study the current mistakes in the context of the interrelations of the formal and factual sciences will be detected and also the human factors that have an influence on the professionals devoted to the development of interactive systems in order to safeguard and boost cultural heritage.

Converging technologies in higher education: paradigm for the "new" liberal arts?

PubMed

Balmer, Robert T

2006-12-01

This article discusses the historic relationship between the practical arts (technology) and the mental (liberal) arts, suggesting that Converging Technologies is a new higher education paradigm that integrates the arts, humanities, and sciences with modern technology. It explains that the paradigm really includes all fields in higher education from philosophy to art to music to modern languages and beyond. To implement a transformation of this magnitude, it is necessary to understand the psychology of change in academia. Union College in Schenectady, New York, implemented a Converging Technologies Educational Paradigm in five steps: (1) create a compelling vision, (2) communicate the vision, (3) empower the faculty, (4) create short-term successes, and (5) institutionalize the results. This case study of Union College demonstrates it is possible to build a pillar of educational excellence based on Converging Technologies.

The role of ADP-ribosylation in regulating DNA interstrand crosslink repair

PubMed Central

Gunn, Alasdair R.; Banos-Pinero, Benito; Paschke, Peggy; Sanchez-Pulido, Luis; Ariza, Antonio; Day, Joseph; Emrich, Mehera; Leys, David; Ponting, Chris P.

2016-01-01

ABSTRACT ADP-ribosylation by ADP-ribosyltransferases (ARTs) has a well-established role in DNA strand break repair by promoting enrichment of repair factors at damage sites through ADP-ribose interaction domains. Here, we exploit the simple eukaryote Dictyostelium to uncover a role for ADP-ribosylation in regulating DNA interstrand crosslink repair and redundancy of this pathway with non-homologous end-joining (NHEJ). In silico searches were used to identify a protein that contains a permutated macrodomain (which we call aprataxin/APLF-and-PNKP-like protein; APL). Structural analysis reveals that this permutated macrodomain retains features associated with ADP-ribose interactions and that APL is capable of binding poly(ADP-ribose) through this macrodomain. APL is enriched in chromatin in response to cisplatin treatment, an agent that induces DNA interstrand crosslinks (ICLs). This is dependent on the macrodomain of APL and the ART Adprt2, indicating a role for ADP-ribosylation in the cellular response to cisplatin. Although adprt2− cells are sensitive to cisplatin, ADP-ribosylation is evident in these cells owing to redundant signalling by the double-strand break (DSB)-responsive ART Adprt1a, promoting NHEJ-mediated repair. These data implicate ADP-ribosylation in DNA ICL repair and identify that NHEJ can function to resolve this form of DNA damage in the absence of Adprt2. PMID:27587838

Art + technology in optics educational outreach programs

NASA Astrophysics Data System (ADS)

Silberman, Donn M.

2007-09-01

In the modern era, art and technology have been at opposite ends of the spectrum of human study. Artists tend to be non-technical and technologists tend not to be artistic. While this is a broad generalization, it is rare to find an artist teaching science or an engineer teaching art. However, if we think back several centuries, it was very common for great artists to be at the forefront of technology. The prime example being the great Leonardo Di Vinci. Over the past several years, the optics educational outreach programs of the Optics Institute of Southern California (OISC) have incorporated using art and artists to help teach optics and related science. The original use of this was with material from the General Atomics Education Foundation, Color My World, which has been used in a number of settings. Recently, the OISC has partnered with the UC Irvine Beall Center for Art + Technology to provide Family Day Event presentations that use the themes of current Art + Technology exhibits to help attendees learn and understand more about the fundamental science through the art. The two main concepts here are that artists are using science and technology as the basis for their art, also sometimes making some social statements; and the technologists are using the art to make the science more accessible and interesting to the general pubic. This paper weaves a path from the original OISC uses of art to the recent work at UC Irvine.

Transcription factors as readers and effectors of DNA methylation.

PubMed

Zhu, Heng; Wang, Guohua; Qian, Jiang

2016-08-01

Recent technological advances have made it possible to decode DNA methylomes at single-base-pair resolution under various physiological conditions. Many aberrant or differentially methylated sites have been discovered, but the mechanisms by which changes in DNA methylation lead to observed phenotypes, such as cancer, remain elusive. The classical view of methylation-mediated protein-DNA interactions is that only proteins with a methyl-CpG binding domain (MBD) can interact with methylated DNA. However, evidence is emerging to suggest that transcription factors lacking a MBD can also interact with methylated DNA. The identification of these proteins and the elucidation of their characteristics and the biological consequences of methylation-dependent transcription factor-DNA interactions are important stepping stones towards a mechanistic understanding of methylation-mediated biological processes, which have crucial implications for human development and disease.

Transcription factors as readers and effectors of DNA methylation

PubMed Central

Zhu, Heng; Wang, Guohua; Qian, Jiang

2017-01-01

Recent technological advances have made it possible to decode DNA methylomes at single-base-pair resolution under various physiological conditions. Many aberrant or differentially methylated sites have been discovered, but the mechanisms by which changes in DNA methylation lead to observed phenotypes, such as cancer, remain elusive. The classical view of methylation-mediated protein-DNA interactions is that only proteins with a methyl-CpG binding domain (MBD) can interact with methylated DNA. However, evidence is emerging to suggest that transcription factors lacking a MBD can also interact with methylated DNA. The identification of these proteins and the elucidation of their characteristics and the biological consequences of methylation-dependent transcription factor-DNA interactions are important stepping stones towards a mechanistic understanding of methylation-mediated biological processes, which have crucial implications for human development and disease. PMID:27479905

Virtual microscopy: merging of computer mediated communication and intuitive interfacing

NASA Astrophysics Data System (ADS)

de Ridder, Huib; de Ridder-Sluiter, Johanna G.; Kluin, Philip M.; Christiaans, Henri H. C. M.

2009-02-01

Ubiquitous computing (or Ambient Intelligence) is an upcoming technology that is usually associated with futuristic smart environments in which information is available anytime anywhere and with which humans can interact in a natural, multimodal way. However spectacular the corresponding scenarios may be, it is equally challenging to consider how this technology may enhance existing situations. This is illustrated by a case study from the Dutch medical field: central quality reviewing for pathology in child oncology. The main goal of the review is to assess the quality of the diagnosis based on patient material. The sharing of knowledge in social face-to-face interaction during such meeting is an important advantage. At the same time there is the disadvantage that the experts from the seven Dutch academic medical centers have to travel to the review meeting and that the required logistics to collect and bring patient material and data to the meeting is cumbersome and time-consuming. This paper focuses on how this time-consuming, nonefficient way of reviewing can be replaced by a virtual collaboration system by merging technology supporting Computer Mediated Collaboration and intuitive interfacing. This requires insight in the preferred way of communication and collaboration as well as knowledge about preferred interaction style with a virtual shared workspace.

Object-Based Teaching and Learning for a Critical Assessment of Digital Technologies in Arts and Cultural Heritage

NASA Astrophysics Data System (ADS)

Hess, M.; Garside, D.; Nelson, T.; Robson, S.; Weyrich, T.

2017-08-01

As cultural sector practice becomes increasingly dependent on digital technologies for the production, display, and dissemination of art and material heritage, it is important that those working in the sector understand the basic scientific principles underpinning these technologies and the social, political and economic implications of exploiting them. The understanding of issues in cultural heritage preservation and digital heritage begins in the education of the future stakeholders and the innovative integration of technologies into the curriculum. This paper gives an example of digital technology skills embedded into a module in the interdisciplinary UCL Bachelor of Arts and Sciences, named "Technologies in Arts and Cultural Heritage", at University College London.

Revolutionizing Arts Education in K-12 Classrooms through Technological Integration

ERIC Educational Resources Information Center

Lemon, Narelle, Ed.

2015-01-01

Educational technologies are becoming more commonplace across the K-12 curriculum. In particular, the use of innovative digital technology is expanding the potential of arts education, presenting new opportunities--and challenges--to both curricular design and pedagogical practice. "Revolutionizing Arts Education in K-12 Classrooms through…

Spin-offs from laser ablation in art conservation

NASA Astrophysics Data System (ADS)

Asmus, J.; Elford, J.; Parfenov, V.

2013-05-01

In 1973 The Center for Art Conservation Studies (CASS) was established at the University of California, San Diego (UCSD). This was in response to demonstrations that were conducted during January-March 1972 in Venice for UNESCO, Venice in Peril, International Fund for Monuments, and the Italian Petroleum Institute (ENI). The feasibility investigation explored in-situ pulsed holography, holographic interferometry, and laser ablation divestment for applications in art conservation practice. During subsequent decades scores of UCSD graduate and undergraduate students as well as conservators, conservation scientists, academics, and engineers who resided in CASS as "Visiting Scholars" contributed to advancing the understanding and performance of radiation technologies in the arts. Several technologies in addition to those involving optical wavelengths were also investigated to aid in art conservation and conservation science. Magnetic Resonance Imaging (MRI) and Nuclear Magnetic Resonance (NMR) were employed to detect and map moisture within masonry. Lead isotopic analyses revealed authenticity and provenance of Benin bronzes. Inside-out x-ray radiography facilitated the detection of defects in stone. Ultrasonic imaging was introduced for the mapping of fresco strata. Photoacoustic Spectroscopy (PAS) was used to characterize varnish layers on paintings. Digital image processing was introduced in order to detect and visualize pentimenti within paintings as well as to perform virtual restoration and provide interactive museum displays. Holographic images were employed as imaginary theater sets. In the years that followed the graduation of students and the visits of professional collaborators, numerous other applications of radiation ablation began appearing in a wide variety of other fields such as aircraft maintenance, ship maintenance, toxic chemical remediation, biological sterilization, food processing, industrial fabrication, industrial maintenance, nuclear decontamination, dermatology, nuclear weapons effects simulation, and graffiti control. It was readily apparent that the customary diffusion of advanced technologies from science and industry into the art conservation field had been reversed. In this paper we trace the migration and adaptation of radiation divestment developments in art conservation to numerous applications in science, industry, and consumer products. Examples described include the robotized hybrid "Flashjet" aircraft paint stripping system, the "Novotronic" anthrax remediation installation in the Pentagon Building, the InTa automated graffiti removal system employing a carbon dioxide TEA laser, the Bellalite body hair removal product incorporating flashlamp technology, and the Foodco line of optical radiation products for the sterilization of food products. The Foodco products are also applied to the sterilization and/or pasteurization of beverages and beverage containers. A similar device has been adapted to seafood irradiation in order to increase shelf life, as well as for the ablative removal of skin and scales. The Goodyear Tire and Rubber Company, to etch logos and identification information into the sidewalls of pneumatic tires, also developed a flashlamp-based ablation technology. The founders of the CYMER Corporation applied UV irradiation technology to the manufacture of high-performance integrated circuits (viz., memory chips, etc.) In several instances former CASS students and Visiting Fellows consciously adapted the above-learned art conservation methodologies to still other purposes. Thus, these examples of technology transfer may be termed: "Art in the service of Science." Alternatively, it is evident that many associated innovations developed from independent activities, unconnected serendipity, or through the normal diffusion of information and knowledge across disciplines.

Theorizing the Nexus of STEAM Practice

ERIC Educational Resources Information Center

Peppler, Kylie; Wohlwend, Karen

2018-01-01

Recent advances in arts education policy, as outlined in the latest National Core Arts Standards, advocate for bringing digital media into the arts education classroom. The promise of such Science, Technology, Engineering, Arts, and Mathematics (STEAM)-based approaches is that, by coupling Science, Technology, Engineering, and Mathematics (STEM)…

Mediating factors in martial arts and combat sports: an analysis of the type of martial art, characteristics, and social background of young participants.

PubMed

Vertonghen, Jikkemien; Theeboom, Marc; Pieter, Willy

2014-02-01

To date, most studies regarding the social-psychological effects of martial arts and combat sports (MA&CS) on young people focus on measuring effects without considering mediating factors. The aim of the present study was to analyze three mediating factors that might be influential when examining outcomes of MA&CS for youth (i.e., the type of MA&CS, participants' characteristics, and social background). Young MA&CS participants (N = 477, M age = 14.0 yr., SD = 2.13) practicing judo, aikido, kick-/Thai boxing or karate, as well as their parents (N = 307), were assessed in terms of their goal orientations, aggressiveness, psychosocial behavior, and social background. It was concluded that differences exist in the characteristics and social background of participants depending on the type of MA&CS being practiced. The fact that differences in these mediating factors can be identified indicates that in future research these and possible other mediating factors should be considered when trying to determine social-psychological outcomes of MA&CS.

Interaction between a pair of gypsy insulators or between heterologous gypsy and Wari insulators modulates Flp site-specific recombination in Drosophila melanogaster.

PubMed

Krivega, Margarita; Savitskaya, Ekaterina; Krivega, Ivan; Karakozova, Marina; Parshikov, Aleksander; Golovnin, Anton; Georgiev, Pavel

2010-08-01

Chromatin insulators block the action of transcriptional enhancers when interposed between an enhancer and a promoter. An Flp technology was used to examine interactions between Drosophila gypsy and Wari insulators in somatic and germ cells. The gypsy insulator consists of 12 binding sites for the Su(Hw) protein, while the endogenous Wari insulator, located on the 3' side of the white gene, is independent from the Su(Hw) protein. Insertion of the gypsy but not Wari insulator between FRT sites strongly blocks recombination between Flp dimers bound to FRT sites located on the same chromatid (recombination in cis) or in sister chromatids (unequal recombination in trans). At the same time, the interaction between Wari and gypsy insulators regulates the efficiency of Flp-mediated recombination. Thus, insulators may have a role in controlling interactions between distantly located protein complexes (not only those involved in transcriptional gene regulation) on the same chromosome or on sister chromatids in somatic and germ cells. We have also found that the frequency of Flp-mediated recombination between FRT sites is strongly dependent on the relative orientation of gypsy insulators. Taken together, our results indicate that the interactions between insulators can be visualized by Flp technology and that insulators may be involved in blocking undesirable interactions between proteins at the two-chromatid phase of the cell cycle.

The therapeutic application of CRISPR/Cas9 technologies for HIV

PubMed Central

Saayman, Sheena; Ali, Stuart A.; Morris, Kevin V.; Weinberg, Marc S.

2015-01-01

Introduction The use of antiretroviral therapy (ART) has led to a significant decrease in morbidity and mortality in HIV-infected individuals. Nevertheless gene-based therapies represent a promising therapeutic paradigm for HIV-1, as they have the potential for sustained viral inhibition and reduced treatment interventions. One new method amendable to a gene-based therapy is the clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 gene editing system. Areas covered CRISPR/Cas9 can be engineered to successfully modulate an array of disease-causing genetic elements. We discuss the diverse roles that CRISPR/Cas9 may play in targeting HIV and eradicating infection. The Cas9 nuclease coupled with one or more small guide RNAs (sgRNAs) can target the provirus to mediate excision of the integrated viral genome. Moreover, a modified nuclease deficient Cas9 fused to transcription activating domains may induce targeted activation of proviral gene expression allowing for the purging of the latent reservoirs. These technologies can also be exploited to target host dependency factors such as the co-receptor CCR5, thus preventing cellular entry of the virus. Expert opinion The diversity of the CRISPR/Cas9 technologies hold great promise for targeting different stages of the viral life cycle, and have the capacity for mediating an effective and sustained genetic therapy against HIV. PMID:25865334

Enhancing Science Literacy and Art History Engagement at Princeton Through Collaboration Between the University Art Museum and the Council on Science and Technology

NASA Astrophysics Data System (ADS)

Riihimaki, C. A.; White, V. M.

2016-12-01

The importance of innovative science education for social science and humanities students is often under-appreciated by science departments, because these students typically do not take science courses beyond general education requirements, nor do they contribute to faculty research programs. However, these students are vitally important in society—for example as business leaders or consultants, and especially as voters. In these roles, they will be confronted with decisions related to science in their professional and personal lives. The Council on Science and Technology at Princeton University aims to fill this education gap by developing and supporting innovative programs that bring science to cross-disciplinary audiences. One of our most fruitful collaborations has been with the Princeton University Art Museum, which has an encyclopedic collection of over 92,000 works of art, ranging from antiquity to the contemporary. Our work includes 1) bringing introductory environmental science courses to the Museum to explore how original works of art of different ages can serve as paleo-environmental proxies, thereby providing a means for discussing broader concepts in development of proxies and validation of reconstructions; 2) sponsoring a panel aimed at the general public and composed of science faculty and art historians who discussed the scientific and art historical contexts behind Albert Bierstadt's Mount Adams, Washington, 1875 (oil on canvas, gift of Mrs. Jacob N. Beam, accession number y1940-430), including the landscape's subjects, materials, technique, and style; and 3) collaborating on an installation of photographs relevant to a freshman GIS course, with an essay about the artwork written by the students. This first-hand study of works of art encourages critical thinking and an empathetic approach to different historical periods and cultures, as well as to the environment. Our collaboration additionally provides an opportunity to engage more students in science and art history concepts, energizes the faculty by providing new opportunities for them to interact with colleagues across the University, and enhances funding requests by broadening the typical audience for Art Museum and science departments.

Technology Education and the Arts

ERIC Educational Resources Information Center

Roman, Harry T.

2009-01-01

One hears quite frequently how the arts continually suffer in the academic day. Many long-time technology education champions certainly know what this is all about; but there may be some ways to use technology education to bring the arts into the classroom. This article offers a series of activities and suggestions that will help students better…

Neurologists and technology: The changing "Facebook" of practice.

PubMed

Potts, Daniel C; Hohler, Anna D

2013-04-01

Social and traditional media are revolutionizing health care. Medicine, once an art practiced behind closed doors, is now part of the public domain. This article will help neurologists navigate a complex maze of technology to optimize patient care without compromising privacy. We offer ideas for improving our digital "footprint." Guidance is given on maintaining professional demeanor in all private and public interactions to help us avoid personal or patient insult and injury. Acknowledging that neurology is becoming a specialty of increased personal and social education, we outline ways to proactively improve our patient care and education locally and globally.

Neurologists and technology

PubMed Central

Potts, Daniel C.; Hohler, Anna D.

2013-01-01

Summary Social and traditional media are revolutionizing health care. Medicine, once an art practiced behind closed doors, is now part of the public domain. This article will help neurologists navigate a complex maze of technology to optimize patient care without compromising privacy. We offer ideas for improving our digital “footprint.” Guidance is given on maintaining professional demeanor in all private and public interactions to help us avoid personal or patient insult and injury. Acknowledging that neurology is becoming a specialty of increased personal and social education, we outline ways to proactively improve our patient care and education locally and globally. PMID:29473595

Optical pump-probe microscopy for biomedicine and art conservation

NASA Astrophysics Data System (ADS)

Fischer, Martin

2013-03-01

Nonlinear optical microscopy can provide contrast in highly heterogeneous media and a wide range of applications has emerged, primarily in biology, medicine, and materials science. Compared to linear microscopy methods, the localized nature of nonlinear interactions leads to high spatial resolution, optical sectioning, and larger possible imaging depth in scattering media. However, nonlinear contrast (other than fluorescence, harmonic generation or CARS) is generally difficult to measure because it is overwhelmed by the large background of detected illumination light. This background can be suppressed by using femtosecond pulse or pulse train shaping to encode nonlinear interactions in background-free regions of the frequency spectrum. We have developed this shaping technology to study novel intrinsic structural and molecular contrast in biological tissue, generally using less power than a laser pointer. For example we have recently been able to sensitively measure detailed transient absorption dynamics of melanin sub-types in a variety of skin lesions, showing clinically relevant differences of melanin type and distribution between cancerous and benign tissue.[1] Recently we have also applied this technology to paint samples and to historic artwork in order to provide detailed, depth-resolved pigment identification. Initial studies in different inorganic and organic pigments have shown a rich and pigment-specific nonlinear absorption signature.[2] Some pigments, for example lapis lazuli (natural ultramarine), even show marked differences in signal depending on its geographic origin and on age, demonstrating the potential of this technique to determine authenticity, provenance, technology of manufacture, or state of preservation of historic works of art.

Accessibility of electronically mediated education: policy issues.

PubMed

Blair, Martin E; Goldmann, Hilary; Relton, Joy

2004-01-01

Electronic technology has transformed education systems over the past 30 years. Generally speaking, technology has been an incredible benefit for individuals with disabilities. However, the use of technology, particularly in education, has been sometimes discriminatory toward those who are unable to interact with it in the standard ways anticipated by its inventors. Disability policies have attempted to address issues of equality of opportunity for all citizens, but application of these policies to rapidly evolving technology has been difficult. In this article we provide a brief review of disability policy as it pertains to education. We also review several current policy initiatives related to higher education information technology--all of which pertain to public kindergarten through 12th-grade education. We raise questions that arise when careful thought is given to ways in which disability, education, and technology policies overlap. We anticipate that these next few pages will generate dialogue among researchers, policy makers, educators, technology engineers, and others interested in how electronically mediated education affects individuals with disabilities and how it can be used to ensure equal access to the educational benefits available in schools protected by U.S. civil rights legislation.

A Mobile-Based E-Learning System

ERIC Educational Resources Information Center

Ojokoh, Bolanle Adefowoke; Doyeni, Olubimtan Ayo; Adewale, Olumide Sunday; Isinkaye, Folasade Olubusola

2013-01-01

E-learning is an innovative approach for delivering electronically mediated, well-designed, learner-centred interactive learning environments by utilizing internet and digital technologies with respect to instructional design principles. This paper presents the application of Software Development techniques in the development of a Mobile Based…

First Things First: Internet Relay Chat Openings.

ERIC Educational Resources Information Center

Rintel, E. Sean; Mulholland, Joan; Pittam, Jeffery

2001-01-01

Argues that Internet Relay Chat (IRC) research needs to systematically address links between interaction structures, technological mediation and the instantiation and development of interpersonal relationships. Finds that openings that occur directly following user's entries into public IRC channels are often ambiguous, can disrupt relationship…

Predictors of Performance in Everyday Technology Tasks in Older Adults With and Without Mild Cognitive Impairment.

PubMed

Schmidt, Laura I; Wahl, Hans-Werner

2018-06-06

The ability to use everyday technology has become a key competence for conducting activities of daily living, maintaining an autonomous life, as well as participating in society. However, studying this issue in older adults needs more attention, particularly among those with mild cognitive impairment (MCI). We assessed the performance of N = 80 older adults (M = 73 years) in a range of tasks representing important life domains, i.e., using a blood pressure monitor, a mobile phone, and an eBook reader. Thirty-nine participants had been diagnosed with MCI by experienced geropsychiatrists and 41 healthy controls were matched for age, sex, and education. Standardized observation based on video-recording and coding was combined with cognitive testing and assessment of social-cognitive variables (self-efficacy, perceived obsolescence, attitudes towards technology). Cognitively healthy participants outperformed those with MCI regarding completion time and errors. An interaction effect of device and study group indicated larger differences in completion time for tasks with multilayered interfaces. In hierarchical regression models, aggregated cognitive factors (fluid and memory component) predicted performance and interactions with education level emerged. Obsolescence, addressing a perceived lack of competence to cope with modern society, mediated the effect of cognitive status on performance, both regarding time (partial mediation, adj.R2 = 28%) and errors (full mediation, adj.R2 = 23%). Findings show that social-cognitive factors contribute to differences in performance on everyday technology tasks in addition to cognitive abilities. Training programs may profit from considering respective individual resources or limitations in the cognitive, personality-related or emotional-motivational domain.

Artemisinin induces ROS-mediated caspase3 activation in ASTC-a-1 cells

NASA Astrophysics Data System (ADS)

Xiao, Feng-Lian; Chen, Tong-Sheng; Qu, Jun-Le; Liu, Cheng-Yi

2010-02-01

Artemisinin (ART), an antimalarial phytochemical from the sweet wormwood plant or a naturally occurring component of Artemisia annua, has been shown a potential anticancer activity by apoptotic pathways. In our report, cell counting kit (CCK-8) assay showed that treatment of human lung adenocarcinoma (ASTC-a-1) cells with ART effectively increase cell death by inducing apoptosis in a time- and dose-dependent fashion. Hoechst 33258 staining was used to detect apoptosis as well. Reactive oxygen species (ROS) generation was observed in cells exposed to ART at concentrations of 400 μM for 48 h. N-acetyl-L-cysteine (NAC), an oxygen radical scavenger, suppressed the rate of ROS generation and inhibited the ART-induced apoptosis. Moreover, AFC assay (Fluorometric assay for Caspase3 activity) showed that ROS was involved in ART-induced caspase3 acitvation. Taken together, our data indicate that ART induces ROS-mediated caspase3 activation in a time-and dose-dependent way in ASCT-a-1 cells.

Boxes with Fires: Wisely Integrating Learning Technologies into the Art Classroom

ERIC Educational Resources Information Center

Gregory, Diane C.

2009-01-01

By integrating and infusing computer learning technologies wisely into student-centered or social constructivist art learning environments, art educators can improve student learning and at the same time provide a creative, substantive model for how schools can and should be reformed. By doing this, art educators have an opportunity to demonstrate…

A Suggested Planned Course in Industrial Arts; Grades 7 and 8. Reprint.

ERIC Educational Resources Information Center

Pennsylvania State Dept. of Education, Harrisburg. Bureau of Curriculum Services.

The Pennsylvania industrial arts curriculum guide for grades 7 and 8 reflects changing philosophy and practices in industrial arts education as well as incorporating the effect of technological changes. Objectives unique to industrial arts education are: (1) to develop literacy in a technological civilization, (2) to develop an insight and…

Digital Masterpieces

ERIC Educational Resources Information Center

Hunter-Doniger, Tracey

2005-01-01

Tracey Hunter-Doniger is an elementary visual arts teacher who is fortunate enough to work in a school that realizes the value and influence art has on technology. Twice a year, her first-through fifth-grade classes meet in the computer lab to create computer-generated works of art. the class discusses the importance of art in technology, such as…

State of the art survey of technologies applicable to NASA's aeronautics, avionics and controls program

NASA Technical Reports Server (NTRS)

Smyth, R. K. (Editor)

1979-01-01

The state of the art survey (SOAS) covers six technology areas including flightpath management, aircraft control system, crew station technology, interface & integration technology, military technology, and fundamental technology. The SOAS included contributions from over 70 individuals in industry, government, and the universities.

Investigation of Personality Traits between Infertile Women Submitted to Assisted Reproductive Technology or Surrogacy.

PubMed

Asgari, Najmeh; Yazdkhasti, Fariba; Nasr Esfahani, Mohammad Hossein

2016-01-01

Personality traits affect human relationships, social interactions, treatment procedures, and essentially all human activities. The purpose of this study is to investigate the personality traitsincluding sensation seeking, flexibility, and happiness among a variety of infertile women who were apt to choose assisted reproductive technology (ART) or surrogacy. This is a cross-sectional study that was performed on 251 infertile women who visited Isfahan and Tehran Reproductive Medicine Center. These fertility clinics are located in Isfahan and Tehran, Iran. In this study, 201 infertile women who underwent treatment using ART and 50 infertile women who tended to have surrogacy were chosen by convenience sampling. Zuckerman's Sensation Seeking Scale Form V (SSS-V), Psychological Flexibility Questionnaire (adapted from NEO Personality Inventory-Revised) and Oxford Happiness Questionnaire (OHQ) were used as research instruments. All participants had to complete the research instruments in order to be included in this study. Data were analyzed by descriptive-analytical statistics and statistical tests including multivariate analysis of variance (MANOVA) and Z Fisher. Statistically significant effects were accepted for P<0.05. In the sensation-seeking variable, there was a meaningful difference between under-study groups. However, the flexibility and happiness variables did not have a significant difference between under-study groups (P<0.001). Interaction between education, employment, and financial status was effective in happiness of infertile women underwent ART (P<0.05), while age, education and financial status were also effective in happiness of infertile women sought surrogacy (P<0.05). A positive meaningful relationship was seen between sensation seeking and flexibility variables in both groups (P<0.05). And a negative meaningful relationship was seen between sensation seeking and happiness in infertile women who sought surrogacy (P<0.05). The difference in rate of relationship between sensation seeking and flexibility was meaningful in infertile women who sought either ART or surrogacy (P<0.05). Sensations seeking as a personality trait is lower in infertile women who underwent treatment using ART compared women who tended to have surrogacy. This study shows that demographic variables are effective in happiness of infertile women. Also, there is a significant relation among sensation seeking, flexibility and happiness in infertile women.

The agency of patients and carers in medical care and self-care technologies for interacting with doctors.

PubMed

Nunes, Francisco; Andersen, Tariq; Fitzpatrick, Geraldine

2017-06-01

People living with Parkinson's disease engage in self-care for most of the time but, two or three times a year, they meet with doctors to re-evaluate the condition and adjust treatment. Patients and (informal) carers participate actively in these encounters, but their engagement might change as new patient-centred technologies are integrated into healthcare infrastructures. Drawing on a qualitative study that used observations and interviews to investigate consultations, and digital ethnography to understand interactions in an online community, we describe how patients and carers living with Parkinson's participate in the diagnosis and treatment decisions, engage in discussions to learn about certain topics, and address inappropriate medication. We contrast their engagement with a review of self-care technologies that support interactions with doctors, to investigate how these artefacts may influence the agency of patients and carers. Finally, we discuss design ideas for improving the participation of patients and carers in technology-mediated scenarios.

The Interactome of the Glucocorticoid Receptor and Its Influence on the Actions of Glucocorticoids in Combatting Inflammatory and Infectious Diseases

PubMed Central

Petta, Ioanna; Dejager, Lien; Ballegeer, Marlies; Lievens, Sam; Tavernier, Jan; Libert, Claude

2016-01-01

SUMMARY Glucocorticoids (GCs) have been widely used for decades as a first-line treatment for inflammatory and autoimmune diseases. However, their use is often hampered by the onset of adverse effects or resistance. GCs mediate their effects via binding to glucocorticoid receptor (GR), a transcription factor belonging to the family of nuclear receptors. An important aspect of GR's actions, including its anti-inflammatory capacity, involves its interactions with various proteins, such as transcription factors, cofactors, and modifying enzymes, which codetermine receptor functionality. In this review, we provide a state-of-the-art overview of the protein-protein interactions (PPIs) of GR that positively or negatively affect its anti-inflammatory properties, along with mechanistic insights, if known. Emphasis is placed on the interactions that affect its anti-inflammatory effects in the presence of inflammatory and microbial diseases. PMID:27169854

Knowledge-based commodity distribution planning

NASA Technical Reports Server (NTRS)

Saks, Victor; Johnson, Ivan

1994-01-01

This paper presents an overview of a Decision Support System (DSS) that incorporates Knowledge-Based (KB) and commercial off the shelf (COTS) technology components. The Knowledge-Based Logistics Planning Shell (KBLPS) is a state-of-the-art DSS with an interactive map-oriented graphics user interface and powerful underlying planning algorithms. KBLPS was designed and implemented to support skilled Army logisticians to prepare and evaluate logistics plans rapidly, in order to support corps-level battle scenarios. KBLPS represents a substantial advance in graphical interactive planning tools, with the inclusion of intelligent planning algorithms that provide a powerful adjunct to the planning skills of commodity distribution planners.

Pathways From HIV-Related Stigma to Antiretroviral Therapy Measures in the HIV Care Cascade for Women Living With HIV in Canada.

PubMed

Logie, Carmen H; Lacombe-Duncan, Ashley; Wang, Ying; Kaida, Angela; Conway, Tracey; Webster, Kath; de Pokomandy, Alexandra; Loutfy, Mona R; Anema, Aranka; Becker, Denise; Brotto, Lori; Carter, Allison; Cardinal, Claudette; Colley, Guillaume; Ding, Erin; Duddy, Janice; Gataric, Nada; Hogg, Robert S; Hosward, Terry; Jabbari, Shahab; Jones, Evin; Kestler, Mary; Langlois, Andrea; Lima, Viviane; Lloyd-Smith, Elisa; Medjuck, Melissa; Miller, Cari; Money, Deborah; Nicholson, Valerie; Ogilvie, Gina; Patterson, Sophie; Pick, Neora; Roth, Eric; Salters, Kate; Sanchez, Margarite; Sas, Jacquie; Sereda, Paul; Summers, Marcie; Tom, Christina; Wang, Lu; Webster, Kath; Zhang, Wendy; Abdul-Noor, Rahma; Angel, Jonathan; Barry, Fatimatou; Bauer, Greta; Beaver, Kerrigan; Benoit, Anita; Bertozzi, Breklyn; Borton, Sheila; Bourque, Tammy; Brophy, Jason; Burchell, Ann; Carlson, Allison; Cioppa, Lynne; Cohen, Jeffrey; Conway, Tracey; Cooper, Curtis; Cotnam, Jasmine; Cousineau, Janette; Fraleigh, Annette; Gagnier, Brenda; Gasingirwa, Claudine; Greene, Saara; Hart, Trevor; Islam, Shazia; Kaushic, Charu; Kennedy, Logan; Kerr, Desiree; Kiboyogo, Maxime; Kwaramba, Gladys; Leonard, Lynne; Lewis, Johanna; Logie, Carmen; Margolese, Shari; Muchenje, Marvelous; Ndungʼu, Mary; OʼBrien, Kelly; Ouellette, Charlene; Powis, Jeff; Quan, Corinna; Raboud, Janet; Rachlis, Anita; Ralph, Edward; Rourke, Sean; Rueda, Sergio; Sandre, Roger; Smaill, Fiona; Smith, Stephanie; Tigere, Tsitsi; Tharao, Wangari; Walmsley, Sharon; Wobeser, Wendy; Yee, Jessica; Yudin, Mark; Baril, Jean-Guy; Burke, Nora Butler; Clément, Pierrette; Dayle, Janice; Dubuc, Danièle; Fernet, Mylène; Groleau, Danielle; Hot, Aurélie; Klein, Marina; Martin, Carrie; Massie, Lyne; Ménard, Brigitte; OʼBrien, Nadia; Otis, Joanne; Peltier, Doris; Pierre, Alie; Proulx-Boucher, Karène; Rouleau, Danielle; Savoie, Édénia; Tremblay, Cécile; Trottier, Benoit; Trottier, Sylvie; Tsoukas, Christos; Gahagan, Jacqueline; Hankins, Catherine; Masching, Renee; Ogunnaike-Cooke, Susanna

2018-02-01

Associations between HIV-related stigma and reduced antiretroviral therapy (ART) adherence are widely established, yet the mechanisms accounting for this relationship are underexplored. There has been less attention to HIV-related stigma and its associations with ART initiation and current ART use. We examined pathways from HIV-related stigma to ART initiation, current ART use, and ART adherence among women living with HIV in Canada. We used baseline survey data from a national cohort of women living with HIV in Canada (n = 1425). Structural equation modeling using weighted least squares estimation methods was conducted to test the direct effects of HIV-related stigma dimensions (personalized, negative self-image, and public attitudes) on ART initiation, current ART use, and 90% ART adherence, and indirect effects through depression and HIV disclosure concerns, adjusting for sociodemographic factors. In the final model, the direct paths from personalized stigma to ART initiation (β = -0.104, P < 0.05) and current ART use (β = -0.142, P < 0.01), and negative self-image to ART initiation (β = -0.113, P < 0.01) were significant, accounting for the mediation effects of depression and HIV disclosure concerns. Depression mediated the pathways from personalized stigma to ART adherence, and negative self-image to current ART use and ART adherence. Final model fit indices suggest that the model fit the data well [χ(25) = 90.251, P < 0.001; comparative fit index = 0.945; root-mean-square error of approximation = 0.044]. HIV-related stigma is associated with reduced likelihood of ART initiation and current ART use, and suboptimal ART adherence. To optimize the benefit of ART among women living with HIV, interventions should reduce HIV-related stigma and address depression.

Assessment of the state of the art in life support environmental control for SEI

NASA Technical Reports Server (NTRS)

Simonds, Charles H.; Noyes, Gary P.

1992-01-01

This paper defines the types of technology that would be used in a lunar base for environmental control and life support system and how it might relate to in situ materials utilization (ISMU) for the Space Exploration Initiative (SEI). There are three types of interaction between ISMU and the Environmental Control and Life Support System (ECLSS): (1) ISMU can reduce cost of water, oxygen, and possibly diluent gasses provided to ECLSS--a corollary to this fact is that the availability of indigenous resources can dramatically alter life support technology trade studies; (2) ISMU can use ECLSS waste systems as a source of reductant carbon and hydrogen; and (3) ECLSS and ISMU, as two chemical processing technologies used in spacecraft, can share technology, thereby increasing the impact of technology investments in either area.

A Survey on Ambient Intelligence in Health Care

PubMed Central

Acampora, Giovanni; Cook, Diane J.; Rashidi, Parisa; Vasilakos, Athanasios V.

2013-01-01

Ambient Intelligence (AmI) is a new paradigm in information technology aimed at empowering people’s capabilities by the means of digital environments that are sensitive, adaptive, and responsive to human needs, habits, gestures, and emotions. This futuristic vision of daily environment will enable innovative human-machine interactions characterized by pervasive, unobtrusive and anticipatory communications. Such innovative interaction paradigms make ambient intelligence technology a suitable candidate for developing various real life solutions, including in the health care domain. This survey will discuss the emergence of ambient intelligence (AmI) techniques in the health care domain, in order to provide the research community with the necessary background. We will examine the infrastructure and technology required for achieving the vision of ambient intelligence, such as smart environments and wearable medical devices. We will summarize of the state of the art artificial intelligence methodologies used for developing AmI system in the health care domain, including various learning techniques (for learning from user interaction), reasoning techniques (for reasoning about users’ goals and intensions) and planning techniques (for planning activities and interactions). We will also discuss how AmI technology might support people affected by various physical or mental disabilities or chronic disease. Finally, we will point to some of the successful case studies in the area and we will look at the current and future challenges to draw upon the possible future research paths. PMID:24431472

A Survey on Ambient Intelligence in Health Care.

PubMed

Acampora, Giovanni; Cook, Diane J; Rashidi, Parisa; Vasilakos, Athanasios V

2013-12-01

Ambient Intelligence (AmI) is a new paradigm in information technology aimed at empowering people's capabilities by the means of digital environments that are sensitive, adaptive, and responsive to human needs, habits, gestures, and emotions. This futuristic vision of daily environment will enable innovative human-machine interactions characterized by pervasive, unobtrusive and anticipatory communications. Such innovative interaction paradigms make ambient intelligence technology a suitable candidate for developing various real life solutions, including in the health care domain. This survey will discuss the emergence of ambient intelligence (AmI) techniques in the health care domain, in order to provide the research community with the necessary background. We will examine the infrastructure and technology required for achieving the vision of ambient intelligence, such as smart environments and wearable medical devices. We will summarize of the state of the art artificial intelligence methodologies used for developing AmI system in the health care domain, including various learning techniques (for learning from user interaction), reasoning techniques (for reasoning about users' goals and intensions) and planning techniques (for planning activities and interactions). We will also discuss how AmI technology might support people affected by various physical or mental disabilities or chronic disease. Finally, we will point to some of the successful case studies in the area and we will look at the current and future challenges to draw upon the possible future research paths.

Parallel Index and Query for Large Scale Data Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chou, Jerry; Wu, Kesheng; Ruebel, Oliver

2011-07-18

Modern scientific datasets present numerous data management and analysis challenges. State-of-the-art index and query technologies are critical for facilitating interactive exploration of large datasets, but numerous challenges remain in terms of designing a system for process- ing general scientific datasets. The system needs to be able to run on distributed multi-core platforms, efficiently utilize underlying I/O infrastructure, and scale to massive datasets. We present FastQuery, a novel software framework that address these challenges. FastQuery utilizes a state-of-the-art index and query technology (FastBit) and is designed to process mas- sive datasets on modern supercomputing platforms. We apply FastQuery to processing ofmore » a massive 50TB dataset generated by a large scale accelerator modeling code. We demonstrate the scalability of the tool to 11,520 cores. Motivated by the scientific need to search for inter- esting particles in this dataset, we use our framework to reduce search time from hours to tens of seconds.« less

A master of arts in chemistry for in-service teachers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crosby, G.A.; Crosby, J.L.

Because many teachers of high school chemistry do not have degrees in that subject, there is a growing need for professional development programs to improve the capacity of practicing teachers to teach modem chemistry competently, safely, and in a manner that engages the interest of the student. Because teachers are place bound (except during the summer) it is difficult to devise programs that meet their needs. At Washington State University we are using a combination of summer laboratory programs and technology during the academic year to deliver instruction to high school teachers. The delivery methods include VCR instruction during themore » academic year via U.S. post, two-way interactive television instruction to cohorts of teachers employed as chemists during summers, and an Electronic Bulletin Board to facilitate information exchange. An outline of the program with emphasis on the problems and benefits, and the degree of acceptance of instructional delivery by technology will be presented. Within three years the teachers earn a Master of Arts in Chemistry.« less

Elementary Core Curriculum Standards: Levels K-3: Arts, Information Technology, Science, Language Arts, Mathematics, Social Studies, Health, Lifestyles.

ERIC Educational Resources Information Center

Utah State Office of Education, Salt Lake City.

Utah's 1987 minimum course description standards for students in kindergarten through third grade are provided in the required core curriculum areas of arts, information technology, science, language arts, mathematics, social studies, and healthy lifestyles. For each curricular area a rationale is given, followed by a brief course description…

A Systems Approach to Technology Education.

ERIC Educational Resources Information Center

Hacker, Michael; Barden, Robert

1983-01-01

Provides a brief history of industrial arts curriculum development, a rationale for a technology-based study of industrial arts, and the use of a systems view in understanding and interpreting technology. (SK)

Episodic Memory and Beyond: The Hippocampus and Neocortex in Transformation

PubMed Central

Moscovitch, Morris; Cabeza, Roberto; Winocur, Gordon; Nadel, Lynn

2016-01-01

The last decade has seen dramatic technological and conceptual changes in research on episodic memory and the brain. New technologies, and increased use of more naturalistic observations, have enabled investigators to delve deeply into the structures that mediate episodic memory, particularly the hippocampus, and to track functional and structural interactions among brain regions that support it. Conceptually, episodic memory is increasingly being viewed as subject to lifelong transformations that are reflected in the neural substrates that mediate it. In keeping with this dynamic perspective, research on episodic memory (and the hippocampus) has infiltrated domains, from perception to language and from empathy to problem solving, that were once considered outside its boundaries. Using the component process model as a framework, and focusing on the hippocampus, its subfields, and specialization along its longitudinal axis, along with its interaction with other brain regions, we consider these new developments and their implications for the organization of episodic memory and its contribution to functions in other domains. PMID:26726963

Episodic Memory and Beyond: The Hippocampus and Neocortex in Transformation.

PubMed

Moscovitch, Morris; Cabeza, Roberto; Winocur, Gordon; Nadel, Lynn

2016-01-01

The last decade has seen dramatic technological and conceptual changes in research on episodic memory and the brain. New technologies, and increased use of more naturalistic observations, have enabled investigators to delve deeply into the structures that mediate episodic memory, particularly the hippocampus, and to track functional and structural interactions among brain regions that support it. Conceptually, episodic memory is increasingly being viewed as subject to lifelong transformations that are reflected in the neural substrates that mediate it. In keeping with this dynamic perspective, research on episodic memory (and the hippocampus) has infiltrated domains, from perception to language and from empathy to problem solving, that were once considered outside its boundaries. Using the component process model as a framework, and focusing on the hippocampus, its subfields, and specialization along its longitudinal axis, along with its interaction with other brain regions, we consider these new developments and their implications for the organization of episodic memory and its contribution to functions in other domains.

Investigation of Technology Integrated Instruction in Art Education: A Case Study of Exploring Learning Achievement

ERIC Educational Resources Information Center

Lee, Szu Hsin; Tseng, Hui Ching

2008-01-01

In today's studies of how computer technologies are used in college art lessons, limited examples are focused on both digital instructional technology design and learning achievement. This study attempts to measure the learning achievement of college students from two intact groups in an art class when a multimedia form of instruction was utilized…

Necessity Is the Mother of Invention: Changing Power Dynamics between Teachers and Students in Wired Art Classrooms

ERIC Educational Resources Information Center

Black, Joanna

2009-01-01

Since 2000, the impact of technologies on society has been critical, significant, and extensive. In this paper, the author explores art educators' perceptions and approaches to working with technology, in light of the emerging technology as a significant and increasingly prevalent art education tool, as a means of student communication, and as a…

Security training with interactive laser-video-disk technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilson, D.

1988-01-01

DOE, through its contractor EG and G Energy Measurements, Inc., has developed a state-of-the-art interactive-video system for use at the Department of Energy's Central Training Academy. Called the Security Training and Evaluation Shooting System (STRESS), the computer-driven decision shooting system employs the latest is laservideo-disk technology. STRESS is designed to provide realistic and stressful training for security inspectors employed by the DOE and its contractors. The system uses wide-screen video projection, sophisticated scenario-branching technology, and customized video scenarios especially designed for the DOE. Firing a weapon that has been modified to shoot ''laser bullets,'' and wearing a special vest thatmore » detects ''hits'': the security inspector encounters adversaries on the wide screen who can shoot or be shot by the inspector in scenarios that demand fast decisions. Based on those decisions, the computer provides instantaneous branching to different scenes, giving the inspector confrontational training with the realism and variability of real life.« less

Effect of Suberoylanilide Hydroxamic Acid (SAHA) Administration on the Residual Virus Pool in a Model of Combination Antiretroviral Therapy-Mediated Suppression in SIVmac239-Infected Indian Rhesus Macaques

PubMed Central

Del Prete, Gregory Q.; Shoemaker, Rebecca; Oswald, Kelli; Lara, Abigail; Trubey, Charles M.; Fast, Randy; Schneider, Douglas K.; Kiser, Rebecca; Coalter, Vicky; Wiles, Adam; Wiles, Rodney; Freemire, Brandi; Keele, Brandon F.; Estes, Jacob D.; Quiñones, Octavio A.; Smedley, Jeremy; Macallister, Rhonda; Sanchez, Rosa I.; Wai, John S.; Tan, Christopher M.; Alvord, W. Gregory; Hazuda, Daria J.; Piatak, Michael

2014-01-01

Nonhuman primate models are needed for evaluations of proposed strategies targeting residual virus that persists in HIV-1-infected individuals receiving suppressive combination antiretroviral therapy (cART). However, relevant nonhuman primate (NHP) models of cART-mediated suppression have proven challenging to develop. We used a novel three-class, six-drug cART regimen to achieve durable 4.0- to 5.5-log reductions in plasma viremia levels and declines in cell-associated viral RNA and DNA in blood and tissues of simian immunodeficiency virus SIVmac239-infected Indian-origin rhesus macaques, then evaluated the impact of treatment with the histone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA; Vorinostat) on the residual virus pool. Ex vivo SAHA treatment of CD4+ T cells obtained from cART-suppressed animals increased histone acetylation and viral RNA levels in culture supernatants. cART-suppressed animals each received 84 total doses of oral SAHA. We observed SAHA dose-dependent increases in acetylated histones with evidence for sustained modulation as well as refractoriness following prolonged administration. In vivo virologic activity was demonstrated based on the ratio of viral RNA to viral DNA in peripheral blood mononuclear cells, a presumptive measure of viral transcription, which significantly increased in SAHA-treated animals. However, residual virus was readily detected at the end of treatment, suggesting that SAHA alone may be insufficient for viral eradication in the setting of suppressive cART. The effects observed were similar to emerging data for repeat-dose SAHA treatment of HIV-infected individuals on cART, demonstrating the feasibility, utility, and relevance of NHP models of cART-mediated suppression for in vivo assessments of AIDS virus functional cure/eradication approaches. PMID:25182644

The need for interaction between assisted reproduction technology and genetics: recommendations of the European Societies of Human Genetics and Human Reproduction and Embryology.

PubMed

2006-08-01

Infertility and reproductive genetic risk are both increasing in our societies because of lifestyle changes and possibly environmental factors. Owing to the magnitude of the problem, they have implications not only at the individual and family levels but also at the community level. This leads to an increasing demand for access to assisted reproduction technology (ART) and genetic services, especially when the cause of infertility may be genetic in origin. The increasing application of genetics in reproductive medicine and vice versa requires closer collaboration between the two disciplines. ART and genetics are rapidly evolving fields where new technologies are currently introduced without sufficient knowledge of their potential long-term effects. As for any medical procedures, there are possible unexpected effects which need to be envisaged to make sure that the balance between benefits and risks is clearly on the benefit side. The development of ART and genetics as scientific activities is creating an opportunity to understand the early stages of human development, which is leading to new and challenging findings/knowledge. However, there are opinions against investigating the early stages of development in humans who deserve respect and attention. For all these reasons, these two societies, European Society of Human Genetics (ESHG) and European Society of Human Reproduction and Embryology (ESHRE), have joined efforts to explore the issues at stake and to set up recommendations to maximize the benefit for the couples in need and for the community.

High-performance holographic technologies for fluid-dynamics experiments

PubMed Central

Orlov, Sergei S.; Abarzhi, Snezhana I.; Oh, Se Baek; Barbastathis, George; Sreenivasan, Katepalli R.

2010-01-01

Modern technologies offer new opportunities for experimentalists in a variety of research areas of fluid dynamics. Improvements are now possible in the state-of-the-art in precision, dynamic range, reproducibility, motion-control accuracy, data-acquisition rate and information capacity. These improvements are required for understanding complex turbulent flows under realistic conditions, and for allowing unambiguous comparisons to be made with new theoretical approaches and large-scale numerical simulations. One of the new technologies is high-performance digital holography. State-of-the-art motion control, electronics and optical imaging allow for the realization of turbulent flows with very high Reynolds number (more than 107) on a relatively small laboratory scale, and quantification of their properties with high space–time resolutions and bandwidth. In-line digital holographic technology can provide complete three-dimensional mapping of the flow velocity and density fields at high data rates (over 1000 frames per second) over a relatively large spatial area with high spatial (1–10 μm) and temporal (better than a few nanoseconds) resolution, and can give accurate quantitative description of the fluid flows, including those of multi-phase and unsteady conditions. This technology can be applied in a variety of problems to study fundamental properties of flow–particle interactions, rotating flows, non-canonical boundary layers and Rayleigh–Taylor mixing. Some of these examples are discussed briefly. PMID:20211881

SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 5: Human Support

NASA Technical Reports Server (NTRS)

1991-01-01

Viewgraphs of briefings from the Space Systems and Technology Advisory Committee (SSTAC)/ARTS review of the draft integrated technology plan (ITP) on human support are included. Topics covered include: human support program; human factors; life support technology; fire safety; medical support technology; advanced refrigeration technology; EVA suit system; advanced PLSS technology; and ARC-EVA systems research program.

Plastic Technology (Production). Industrial Arts, Senior High--Level II. North Dakota Senior High Industrial Arts Curriculum Guides.

ERIC Educational Resources Information Center

Claus, Robert; And Others

This course guide for a plastic technology course is one of four developed for the production area in the North Dakota senior high industrial arts education program. (Eight other guides are available for two other areas of Industrial Arts--energy/power and graphic communications.) Part 1 provides such introductory information as a definition and…

Wood Technology (Production). Industrial Arts, Senior High--Level II. North Dakota Senior High Industrial Arts Curriculum Guides.

ERIC Educational Resources Information Center

Claus, Robert; And Others

This course guide for a wood technology course is one of four developed for the production area in the North Dakota senior high industrial arts education program. (Eight other guides are available for two other areas of Industrial Arts--energy/power and graphic communications.) Part 1 provides such introductory information as a definition and…

Does the medium matter? The interaction of task type and technology on group performance and member reactions.

PubMed

Straus, S G; McGrath, J E

1994-02-01

The authors investigated the hypothesis that as group tasks pose greater requirements for member interdependence, communication media that transmit more social context cues will foster group performance and satisfaction. Seventy-two 3-person groups of undergraduate students worked in either computer-mediated or face-to-face meetings on 3 tasks with increasing levels of interdependence: an idea-generation task, an intellective task, and a judgment task. Results showed few differences between computer-mediated and face-to-face groups in the quality of the work completed but large differences in productivity favoring face-to-face groups. Analysis of productivity and of members' reactions supported the predicted interaction of tasks and media, with greater discrepancies between media conditions for tasks requiring higher levels of coordination. Results are discussed in terms of the implications of using computer-mediated communications systems for group work.

The Ethical, Legal, and Social Issues Impacted by Modern Assisted Reproductive Technologies

PubMed Central

Brezina, Paul R.; Zhao, Yulian

2012-01-01

Background. While assisted reproductive technology (ART), including in vitro fertilization has given hope to millions of couples suffering from infertility, it has also introduced countless ethical, legal, and social challenges. The objective of this paper is to identify the aspects of ART that are most relevant to present-day society and discuss the multiple ethical, legal, and social challenges inherent to this technology. Scope of Review. This paper evaluates some of the most visible and challenging topics in the field of ART and outlines the ethical, legal, and social challenges they introduce. Major Conclusions. ART has resulted in a tectonic shift in the way physicians and the general population perceive infertility and ethics. In the coming years, advancing technology is likely to exacerbate ethical, legal, and social concerns associated with ART. ART is directly challenging society to reevaluate the way in which human life, social justice and equality, and claims to genetic offspring are viewed. Furthermore, these issues will force legal systems to modify existing laws to accommodate the unique challenges created by ART. Society has a responsibility to ensure that the advances achieved through ART are implemented in a socially responsible manner. PMID:22272208

Industrial Arts Test Development, Book III. Resource Items for Graphics Technology, Power Technology, Production Technology.

ERIC Educational Resources Information Center

New York State Education Dept., Albany.

This booklet is designed to assist teachers in developing examinations for classroom use. It is a collection of 955 objective test questions, mostly multiple choice, for industrial arts students in the three areas of graphics technology, power technology, and production technology. Scoring keys are provided. There are no copyright restrictions,…

Impact of food, housing, and transportation insecurity on ART adherence: a hierarchical resources approach.

PubMed

Cornelius, Talea; Jones, Maranda; Merly, Cynthia; Welles, Brandi; Kalichman, Moira O; Kalichman, Seth C

2017-04-01

Antiretroviral therapy (ART) has transformed HIV into a manageable illness. However, high levels of adherence must be maintained. Lack of access to basic resources (food, transportation, and housing) has been consistently associated with suboptimal ART adherence. Moving beyond such direct effects, this study takes a hierarchical resources approach in which the effects of access to basic resources on ART adherence are mediated through interpersonal resources (social support and care services) and personal resources (self-efficacy). Participants were 915 HIV-positive men and women living in Atlanta, GA, recruited from community centers and infectious disease clinics. Participants answered baseline questionnaires, and provided prospective data on ART adherence. Across a series of nested models, a consistent pattern emerged whereby lack of access to basic resources had indirect, negative effects on adherence, mediated through both lack of access to social support and services, and through lower treatment self-efficacy. There was also a significant direct effect of lack of access to transportation on adherence. Lack of access to basic resources negatively impacts ART adherence. Effects for housing instability and food insecurity were fully mediated through social support, access to services, and self-efficacy, highlighting these as important targets for intervention. Targeting service supports could be especially beneficial due to the potential to both promote adherence and to link clients with other services to supplement food, housing, and transportation. Inability to access transportation had a direct negative effect on adherence, suggesting that free or reduced cost transportation could positively impact ART adherence among disadvantaged populations.

Strategic Use of Modality during Synchronous CMC

ERIC Educational Resources Information Center

Sauro, Shannon

2009-01-01

Research on computer-mediated communication (CMC) in the second language (L2) classroom has revealed the potential for technology to promote learner interaction and opportunities for negotiation of meaning as well as to provide opportunities for language access outside the classroom environment. Despite this potential, social, linguistic, and…

Combustor liner durability analysis

NASA Technical Reports Server (NTRS)

Moreno, V.

1981-01-01

An 18 month combustor liner durability analysis program was conducted to evaluate the use of advanced three dimensional transient heat transfer and nonlinear stress-strain analyses for modeling the cyclic thermomechanical response of a simulated combustor liner specimen. Cyclic life prediction technology for creep/fatigue interaction is evaluated for a variety of state-of-the-art tools for crack initiation and propagation. The sensitivity of the initiation models to a change in the operating conditions is also assessed.

Development of interactive multimedia applications

NASA Technical Reports Server (NTRS)

Leigh, Albert; Wang, Lui

1993-01-01

Multimedia is making an increasingly significant contribution to our informational society. The usefulness of this technology is already evident in education, business presentations, informational kiosks (e.g., in museums), training and the entertainment environment. Institutions, from grade schools to medical schools, are exploring the use of multifaceted electronic text books and teaching aids to enhance course materials. Through multimedia, teachers and students can take full advantage of the cognitive value of animation, audio, video and other types in a seamless application. The Software Technology Branch at NASA Johnson Space Center (NASA/JSC) is taking similar approaches to apply the state-of-the-art technology to space training, mission operations and other applications. This paper discusses the characteristics and development of multimedia applications at the NASA/JSC.

Technological Literacy: The Roles of Practical Arts and Vocational Education. Proceedings from an International Symposium on Technological Literacy (Columbus, Ohio, May 13-15, 1987).

ERIC Educational Resources Information Center

Blankenbaker, E. Keith, Ed.; Miller, Aaron J., Ed.

The following papers are included: "Technological Literacy: What? Why? For Whom?" (Kranzberg); "Techniliterate vs. Technilliterate (There's an L of a Difference)" (Stone); "International Perspectives on Technological Literacy" (Dyrenfurth); "Technology and the Liberal Arts: Are We Producing Technopeasants?"…

2-in-1 shampoo technology: state-of-the-art shampoo and conditioner in one.

PubMed

Rushton, H; Gummer, C L; Flasch, H

1994-01-01

Consumers have expressed a need for cleaning and conditioning in one step. Conventional shampoo technology using anionic surfactants and cationic conditioners results in charge interaction and complexing of the ingredients. Neither shampoo nor conditioners achieves the desired result. The successful solution was to incorporate charge neutral dimethicone conditioning ingredients, suspended as microfine droplets within complex crystal lattices, into anionic surfactant shampoo technology. The same solution has also been applied to amphoteric surfactant systems. This provides complete cleaning, and hair conditioning fully equal to separate conditioners without the problems of sebum interactions and conditioner build-up. This was achieved by keeping the dimethicone in suspension throughout the shampoo process. During rinsing, excess water breaks the crystalline lattice and allows deposition of the dimethicone droplets onto the hair. Full cleaning and conditioning are, therefore, achieved in one application. Dimethicone build-up is not encountered as subsequent washes first remove soil and previously deposited dimethicone. Neither do neutral dimethicones show any reactions with sebum. The development of effective 2-in-1 technology has had a major impact on shampoo technology and consumer habits and practices. This has significantly changed the way consumers care for their hair.

SMART Power Systems for ANTS Missions

NASA Astrophysics Data System (ADS)

Clark, P. E.; Floyd, S. R.; Curtis, S. A.; Rilee, M. L.

2005-02-01

Autonomous NanoTechnology Swarm (ANTS) Architecture is based on Addressable Reconfigurable Technology (ART) adaptable for the full spectrum of activities in space. ART systems based on currently available electromechanical (EMS) technology could support human crews on the lunar surface within the next 10 to 15 years. Two or more decades from now, NEMS (Super Miniaturized ART or SMART) technology could perform fully autonomous surveys and operations beyond the reach of human crews. Power system requirements would range from 1 kg to generate tens of Watts for near term ART applications, such as a lunar or Mars Lander Amorphous Rover Antenna (LARA), to <0.1 kg to generate hundreds of mWatts for more advanced SMART applications.

ENGage: The use of space and pixel art for increasing primary school children's interest in science, technology, engineering and mathematics

NASA Astrophysics Data System (ADS)

Roberts, Simon J.

2014-01-01

The Faculty of Engineering at The University of Nottingham, UK, has developed interdisciplinary, hands-on workshops for primary schools that introduce space technology, its relevance to everyday life and the importance of science, technology, engineering and maths. The workshop activities for 7-11 year olds highlight the roles that space and satellite technology play in observing and monitoring the Earth's biosphere as well as being vital to communications in the modern digital world. The programme also provides links to 'how science works', the environment and citizenship and uses pixel art through the medium of digital photography to demonstrate the importance of maths in a novel and unconventional manner. The interactive programme of activities provides learners with an opportunity to meet 'real' scientists and engineers, with one of the key messages from the day being that anyone can become involved in science and engineering whatever their ability or subject of interest. The methodology introduces the role of scientists and engineers using space technology themes, but it could easily be adapted for use with any inspirational topic. Analysis of learners' perceptions of science, technology, engineering and maths before and after participating in ENGage showed very positive and significant changes in their attitudes to these subjects and an increase in the number of children thinking they would be interested and capable in pursuing a career in science and engineering. This paper provides an overview of the activities, the methodology, the evaluation process and results.

Liberal Education and Technology.

ERIC Educational Resources Information Center

Brown, Peggy Ann, Ed.

1985-01-01

Projects at liberal arts colleges to help students understand technology, most of which were funded by the Alfred P. Sloan Foundations' New Liberal Arts Program, are described. Also included are John G. Truxal's essay, "Thoughts on Teaching Technology," which includes an illustration of technological problems/solutions posed by the pacemaker. The…

Introduction to the Special Issue on "State-of-the-Art Sensor Technology in Japan 2015".

PubMed

Tokumitsu, Masahiro; Ishida, Yoshiteru

2016-08-23

This Special Issue, "State-of-the-Art Sensor Technology in Japan 2015", collected papers on different kinds of sensing technology: fundamental technology for intelligent sensors, information processing for monitoring humans, and information processing for adaptive and survivable sensor systems.[...].

Industrial Arts and Technology, Past, Present, and Future; Addresses and Proceedings of the American Industrial Arts Association's Annual Convention (29th, Philadelphia, 1967).

ERIC Educational Resources Information Center

American Industrial Arts Association, Washington, DC.

Manuscripts of 158 individual conference presentations are included. Speeches in each general session were centered on one of the following major topics--(1) Philosophical Bases of Industrial Arts--Four Poles, (2) Industrial Arts and the National Image, (3) The Cultural and Educational Heritage of Our Technological Society, (4) How and Where Can…

Power Technology (Energy/Power). Industrial Arts, Senior High--Level II. North Dakota Senior High Industrial Arts Curriculum Guides.

ERIC Educational Resources Information Center

Lawrence, Allen; And Others

This course guide for a power technology course is one of four developed for the energy/power area in the North Dakota senior high industrial arts education program. (Eight other guides are available for two other areas of Industrial Arts--graphic communications and production.) Part 1 provides such introductory information as a definition and…

Electrical/Electronic Technology (Energy/Power). Industrial Arts, Senior High--Level II. North Dakota Senior High Industrial Arts Curriculum Guides.

ERIC Educational Resources Information Center

Lawrence, Allen; And Others

This course guide for an electrical/electronic technology course is one of four developed for the energy/power area in the North Dakota senior high industrial arts education program. (Eight other guides are available for two other areas of Industrial Arts--graphic communications and production.) Part 1 provides such introductory information as a…

Germ line genome editing in clinics: the approaches, objectives and global society.

PubMed

Ishii, Tetsuya

2017-01-01

Genome editing allows for the versatile genetic modification of somatic cells, germ cells and embryos. In particular, CRISPR/Cas9 is worldwide used in biomedical research. Although the first report on Cas9-mediated gene modification in human embryos focused on the prevention of a genetic disease in offspring, it raised profound ethical and social concerns over the safety of subsequent generations and the potential misuse of genome editing for human enhancement. The present article considers germ line genome editing approaches from various clinical and ethical viewpoints and explores its objectives. The risks and benefits of the following three likely objectives are assessed: the prevention of monogenic diseases, personalized assisted reproductive technology (ART) and genetic enhancement. Although genetic enhancement should be avoided, the international regulatory landscape suggests the inevitability of this misuse at ART centers. Under these circumstances, possible regulatory responses and the potential roles of public dialogue are discussed. © The Author 2015. Published by Oxford University Press.

Brain-computer interface after nervous system injury.

PubMed

Burns, Alexis; Adeli, Hojjat; Buford, John A

2014-12-01

Brain-computer interface (BCI) has proven to be a useful tool for providing alternative communication and mobility to patients suffering from nervous system injury. BCI has been and will continue to be implemented into rehabilitation practices for more interactive and speedy neurological recovery. The most exciting BCI technology is evolving to provide therapeutic benefits by inducing cortical reorganization via neuronal plasticity. This article presents a state-of-the-art review of BCI technology used after nervous system injuries, specifically: amyotrophic lateral sclerosis, Parkinson's disease, spinal cord injury, stroke, and disorders of consciousness. Also presented is transcending, innovative research involving new treatment of neurological disorders. © The Author(s) 2014.

Semantic web for integrated network analysis in biomedicine.

PubMed

Chen, Huajun; Ding, Li; Wu, Zhaohui; Yu, Tong; Dhanapalan, Lavanya; Chen, Jake Y

2009-03-01

The Semantic Web technology enables integration of heterogeneous data on the World Wide Web by making the semantics of data explicit through formal ontologies. In this article, we survey the feasibility and state of the art of utilizing the Semantic Web technology to represent, integrate and analyze the knowledge in various biomedical networks. We introduce a new conceptual framework, semantic graph mining, to enable researchers to integrate graph mining with ontology reasoning in network data analysis. Through four case studies, we demonstrate how semantic graph mining can be applied to the analysis of disease-causal genes, Gene Ontology category cross-talks, drug efficacy analysis and herb-drug interactions analysis.

Determination of the element-specific complex permittivity using a soft x-ray phase modulator

NASA Astrophysics Data System (ADS)

Kubota, Y.; Hirata, Y.; Miyawaki, J.; Yamamoto, S.; Akai, H.; Hobara, R.; Yamamoto, Sh.; Yamamoto, K.; Someya, T.; Takubo, K.; Yokoyama, Y.; Araki, M.; Taguchi, M.; Harada, Y.; Wadati, H.; Tsunoda, M.; Kinjo, R.; Kagamihata, A.; Seike, T.; Takeuchi, M.; Tanaka, T.; Shin, S.; Matsuda, I.

2017-12-01

We report on directly determining the complex permittivity tensor using a method combining a developed light source from a segmented cross undulator of synchrotron radiation and the magneto-optical Kerr effect. The empirical permittivity, which carries the electronic and magnetic information of a material, has element specificity and has perfect confirmation using the quantum-mechanical calculation for itinerant electrons systems. These results help in understanding the interaction of light and matter, and they provide an interesting approach to seek the best materials as optical elements, for example, in extended-ultraviolet lithographic technologies or in state-of-the-art laser technologies.

Platelet–neutrophil interactions under thromboinflammatory conditions

PubMed Central

Li, Jing; Kim, Kyungho; Barazia, Andrew; Tseng, Alan

2015-01-01

Platelets primarily mediate hemostasis and thrombosis, whereas leukocytes are responsible for immune responses. Since platelets interact with leukocytes at the site of vascular injury, thrombosis and vascular inflammation are closely intertwined and occur consecutively. Recent studies using real-time imaging technology demonstrated that platelet–neutrophil interactions on the activated endothelium are an important determinant of microvascular occlusion during thromboinflammatory disease in which inflammation is coupled to thrombosis. Although the major receptors and counter receptors have been identified, it remains poorly understood how heterotypic platelet–neutrophil interactions are regulated under disease conditions. This review discusses our current understanding of the regulatory mechanisms of platelet– neutrophil interactions in thromboinflammatory disease. PMID:25650236

Conversation Analysis in Computer-Assisted Language Learning

ERIC Educational Resources Information Center

González-Lloret, Marta

2015-01-01

The use of Conversation Analysis (CA) in the study of technology-mediated interactions is a recent methodological addition to qualitative research in the field of Computer-assisted Language Learning (CALL). The expansion of CA in Second Language Acquisition research, coupled with the need for qualitative techniques to explore how people interact…

Instrumental and Documentational Approaches: From Technology Use to Documentation Systems in University Mathematics Education

ERIC Educational Resources Information Center

Gueudet, Ghislaine; Buteau, Chantal; Mesa, Vilma; Misfeldt, Morten

2014-01-01

In this article we present an "instrumental approach" in mathematics education, which focuses on the interactions between students, teachers, and "artefacts." This approach analyses "mediations" attached to the use of a given artefact and "instruments" developed by the subjects from this artefact along…

University ESL Learners' Cross-Cultural Transitions through Web-Based Project Work

ERIC Educational Resources Information Center

Kang, Migyu; Bruna, Katherine Richardson

2013-01-01

This study sought to account for East Asian learners' cross-cultural transitions to US university Intensive English classroom culture within a technology-mediated language teaching approach, PrOCALL (Project-Oriented Computer Assisted Language Learning). It explored the influence of this approach on classroom interaction patterns acquired in the…

Power, Voice and Democratization: Feminist Pedagogy and Assessment in CMC.

ERIC Educational Resources Information Center

Campbell, Katy

2002-01-01

Discussion of differences in the ways that female and male faculty approach the use of technology in teaching focuses on a study of female faculty learning design preferences in critical feminist teaching. Considers learner-centered approaches; interactions with students in computer-mediated communication (CMC); democratization in online…

Teaching with Distance Delivery Systems: Strategies from Alpha to Omega.

ERIC Educational Resources Information Center

Rezabek, Landra L.

Distance education can assume many forms, including videotaped lectures, computer-mediated communication among teacher and student, and instantaneous, live two-way interaction. This paper focuses on tips and strategies for educators wishing to expand their teaching repertoires to include the use of these technologies. Teacher strategies listed…

Activity Theory and Qualitative Research in Digital Domains

ERIC Educational Resources Information Center

Sam, Cecile

2012-01-01

Understanding the interactions between people, computer-mediated communication, and online life requires that researchers appropriate a set of methodological tools that would be best suited for capturing and analyzing the phenomenon. However, these tools are not limited to relevant technological forms of data collections and analysis programs; it…

Educating Avatars: On Virtual Worlds and Pedagogical Intent

ERIC Educational Resources Information Center

Wang, Tsung Juang

2011-01-01

Virtual world technology is now being incorporated into various higher education programs, often with enthusiastic claims about the improvement of students' abilities to experience learning problems and tasks in computer-mediated virtual reality through the use of computer-generated personal agents or avatars. The interactivity of the avatars with…

Sonic Onyx: Case Study of an Interactive Artwork

NASA Astrophysics Data System (ADS)

Ahmed, Salah Uddin; Jaccheri, Letizia; M'kadmi, Samir

Software supported art projects are increasing in numbers in recent years as artists are exploring how computing can be used to create new forms of live art. Interactive sound installation is one kind of art in this genre. In this article we present the development process and functional description of Sonic Onyx, an interactive sound installation. The objective is to show, through the life cycle of Sonic Onyx, how a software dependent interactive artwork involves its users and raises issues related to its interaction and functionalities.

The impact of active controls technology on the structural integrity of aeronautical vehicles

NASA Technical Reports Server (NTRS)

Noll, Thomas E.; Austin, Edward; Donley, Shawn; Graham, George; Harris, Terry; Kaynes, Ian; Lee, Ben; Sparrow, James

1993-01-01

The findings of an investigation conducted under the auspices of The Technical Cooperation Program (TTCP) to assess the impact of active controls technology on the structural integrity of aeronautical vehicles and to evaluate the present state-of-the-art for predicting loads caused by a flight-control system modification and the resulting change in the fatigue life of the flight vehicle are summarized. Important points concerning structural technology considerations implicit in applying active controls technology in new aircraft are summarized. These points are well founded and based upon information received from within the aerospace industry and government laboratories, acquired by sponsoring workshops which brought together experts from contributing and interacting technical disciplines, and obtained by conducting a case study to independently assess the state of the technology. The paper concludes that communication between technical disciplines is absolutely essential in the design of future high performance aircraft.

Selected Colorado Technology Education Programs.

ERIC Educational Resources Information Center

Gloeckner, Gene W.

The transition from industrial arts to technology education is a priority in Colorado. Millions of dollars have been and will be spent to renovate industrial arts facilities and laboratories. Four Colorado middle schools have exemplary technology education programs. The Eagle Crest Technology Education Laboratory is used for both middle and high…

Permuting the PGF Signature Motif Blocks both Archaeosortase-Dependent C-Terminal Cleavage and Prenyl Lipid Attachment for the Haloferax volcanii S-Layer Glycoprotein.

PubMed

Abdul Halim, Mohd Farid; Karch, Kelly R; Zhou, Yitian; Haft, Daniel H; Garcia, Benjamin A; Pohlschroder, Mechthild

2015-12-28

For years, the S-layer glycoprotein (SLG), the sole component of many archaeal cell walls, was thought to be anchored to the cell surface by a C-terminal transmembrane segment. Recently, however, we demonstrated that the Haloferax volcanii SLG C terminus is removed by an archaeosortase (ArtA), a novel peptidase. SLG, which was previously shown to be lipid modified, contains a C-terminal tripartite structure, including a highly conserved proline-glycine-phenylalanine (PGF) motif. Here, we demonstrate that ArtA does not process an SLG variant where the PGF motif is replaced with a PFG motif (slg(G796F,F797G)). Furthermore, using radiolabeling, we show that SLG lipid modification requires the PGF motif and is ArtA dependent, lending confirmation to the use of a novel C-terminal lipid-mediated protein-anchoring mechanism by prokaryotes. Similar to the case for the ΔartA strain, the growth, cellular morphology, and cell wall of the slg(G796F,F797G) strain, in which modifications of additional H. volcanii ArtA substrates should not be altered, are adversely affected, demonstrating the importance of these posttranslational SLG modifications. Our data suggest that ArtA is either directly or indirectly involved in a novel proteolysis-coupled, covalent lipid-mediated anchoring mechanism. Given that archaeosortase homologs are encoded by a broad range of prokaryotes, it is likely that this anchoring mechanism is widely conserved. Prokaryotic proteins bound to cell surfaces through intercalation, covalent attachment, or protein-protein interactions play critical roles in essential cellular processes. Unfortunately, the molecular mechanisms that anchor proteins to archaeal cell surfaces remain poorly characterized. Here, using the archaeon H. volcanii as a model system, we report the first in vivo studies of a novel protein-anchoring pathway involving lipid modification of a peptidase-processed C terminus. Our findings not only yield important insights into poorly understood aspects of archaeal biology but also have important implications for key bacterial species, including those of the human microbiome. Additionally, insights may facilitate industrial applications, given that photosynthetic cyanobacteria encode uncharacterized homologs of this evolutionarily conserved enzyme, or may spur development of unique drug delivery systems. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

A Review of Multi-Sensory Technologies in a Science, Technology, Engineering, Arts and Mathematics (STEAM) Classroom

ERIC Educational Resources Information Center

Taljaard, Johann

2016-01-01

This article reviews the literature on multi-sensory technology and, in particular, looks at answering the question: "What multi-sensory technologies are available to use in a science, technology, engineering, arts and mathematics (STEAM) classroom, and do they affect student engagement and learning outcomes?" Here engagement is defined…

Technology and Thematic Units: A Primary Example (Technology Links to Literacy).

ERIC Educational Resources Information Center

Wepner, Shelley B.

1992-01-01

Uses a teacher's thematic unit on endangered species to share how technology can help to make meaningful connections across the curriculum. Shows how the unit includes science, social studies, mathematics, art, language arts, and music. (SR)

Advanced Rotorcraft Transmission (ART) program summary

NASA Technical Reports Server (NTRS)

Krantz, T. L.; Kish, J. G.

1992-01-01

The Advanced Rotorcraft Transmission (ART) Program was initiated to advance the state of the art for rotorcraft transmissions. The goal of the ART Program was to develop and demonstrate the technologies needed to reduce transmission weight by 25 pct. and reduce noise by 10 dB while obtaining a 5000 hr 'mean time between failure'. The research done under the ART Program is summarized. A split path design was selected as best able to meet the program goals. Key part technologies needed for this design were identified, studied, and developed. Two of these technologies are discussed in detail: the load sharing of split path designs including the use of a compliant elastomeric torque splitter and the application of a high ratio, low pitch line velocity gear mesh. Development of an angular contact spherical roller bearing, transmission error analysis, and fretting fatigue testing are discussed. The technologies for a light weight, quiet, and reliable rotorcraft transmission were demonstrated.

Association Between Internalized HIV-Related Stigma and HIV Care Visit Adherence.

PubMed

Rice, Whitney S; Crockett, Kaylee B; Mugavero, Michael J; Raper, James L; Atkins, Ghislaine C; Turan, Bulent

2017-12-15

Internalized HIV-related stigma acts as a barrier to antiretroviral therapy (ART) adherence, but its effects on other HIV care continuum outcomes are unclear. Among 196 HIV clinic patients in Birmingham, AL, we assessed internalized HIV-related stigma and depressive symptom severity using validated multi-item scales and assessed ART adherence using a validated single-item measure. HIV visit adherence (attended out of total scheduled visits) was calculated using data from clinic records. Using covariate-adjusted regression analysis, we investigated the association between internalized stigma and visit adherence. Using path analytic methods with bootstrapping, we tested the mediating role of depressive symptoms in the association between internalized stigma and visit adherence and the mediating role of visit adherence in the association between internalized stigma and ART adherence. Higher internalized stigma was associated with lower visit adherence (B = -0.04, P = 0.04). Black (versus white) race and depressive symptoms were other significant predictors within this model. Mediation analysis yielded no indirect effect through depression in the association between internalized stigma and visit adherence (B = -0.18, SE = 0.11, 95% confidence interval: -0.44 to -0.02) in the whole sample. Supplemental mediated moderation analyses revealed gender-specific effects. Additionally, the effect of internalized stigma on suboptimal ART adherence was mediated by lower visit adherence (B = -0.18, SE = 0.11, 95% confidence interval: -0.44 to -0.02). Results highlight the importance of internalized HIV stigma to multiple and sequential HIV care continuum outcomes. Also, findings suggest multiple intervention targets, including addressing internalized stigma directly, reducing depressive symptoms, and promoting consistent engagement in care.

76 FR 9610 - National Endowment for the Arts; Submission of OMB Review: Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-18

... technological collection techniques, or other forms of information technology, e.g., permitting electronic... in the Arts. OMB Number: New. Frequency: One Time. Affected Public: American adults. Estimated Number... sectional survey of individual attendance and involvement in arts and cultural activity. The data are...

STEAM by Another Name: Transdisciplinary Practice in Art and Design Education

ERIC Educational Resources Information Center

Costantino, Tracie

2018-01-01

The recent movement to include art and design in Science, Technology, Engineering, and Mathematics (STEM) education has made Science, Technology, Engineering, Arts, and Mathematics (STEAM) an increasingly common acronym in the education lexicon. The STEAM movement builds on existing models of interdisciplinary curriculum, but what makes the union…

Artistic Ways of Knowing in Gifted Education: Encouraging Every Student to Think Like an Artist

ERIC Educational Resources Information Center

Haroutounian, Joanne

2017-01-01

After decades of fluctuating presence in gifted education, the arts are surprisingly establishing themselves in academic classrooms, spurred by arts integration with science, technology, engineering, and mathematics (STEM) curricula or science, technology, engineering, art, and mathematics (STEAM). This renewed interest provides the opportunity to…

Kids as Curators: Virtual Art at the Seattle Museum.

ERIC Educational Resources Information Center

Scanlan, Laura Wolff

2000-01-01

Discusses the use of technology at the Seattle Art Museum (Washington). Includes a Web site that enables students in grades six through ten to act as curators and offers integrations of technology in the exhibition "Leonardo Lives: The Codex Leicester and Leonardo da Vinci's Legacy of Art and Science." (CMK)

Innovative Technology for Teaching Introductory Astronomy

NASA Astrophysics Data System (ADS)

Guidry, Mike

The application of state-of-the-art technology (primarily Java and Flash MX Actionscript on the client side and Java PHP PERL XML and SQL databasing on the server side) to the teaching of introductory astronomy will be discussed. A completely online syllabus in introductory astronomy built around more than 350 interactive animations called ""Online Journey through Astronomy"" and a new set of 20 online virtual laboratories in astronomy that we are currently developing will be used as illustration. In addition to demonstration of the technology our experience using these technologies to teach introductory astronomy to thousands of students in settings ranging from traditional classrooms to full distance learning will be summarized. Recent experiments using Java and vector graphics programming of handheld devices (Personal Digital Assistants and cell phones) with wireless wide-area connectivity for applications in astronomy education will also be described.

Simulator platform for fast reactor operation and safety technology demonstration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vilim, R. B.; Park, Y. S.; Grandy, C.

2012-07-30

A simulator platform for visualization and demonstration of innovative concepts in fast reactor technology is described. The objective is to make more accessible the workings of fast reactor technology innovations and to do so in a human factors environment that uses state-of-the art visualization technologies. In this work the computer codes in use at Argonne National Laboratory (ANL) for the design of fast reactor systems are being integrated to run on this platform. This includes linking reactor systems codes with mechanical structures codes and using advanced graphics to depict the thermo-hydraulic-structure interactions that give rise to an inherently safe responsemore » to upsets. It also includes visualization of mechanical systems operation including advanced concepts that make use of robotics for operations, in-service inspection, and maintenance.« less

Teaching and Learning in the Mixed-Reality Science Classroom

NASA Astrophysics Data System (ADS)

Tolentino, Lisa; Birchfield, David; Megowan-Romanowicz, Colleen; Johnson-Glenberg, Mina C.; Kelliher, Aisling; Martinez, Christopher

2009-12-01

As emerging technologies become increasingly inexpensive and robust, there is an exciting opportunity to move beyond general purpose computing platforms to realize a new generation of K-12 technology-based learning environments. Mixed-reality technologies integrate real world components with interactive digital media to offer new potential to combine best practices in traditional science learning with the powerful affordances of audio/visual simulations. This paper introduces the realization of a learning environment called SMALLab, the Situated Multimedia Arts Learning Laboratory. We present a recent teaching experiment for high school chemistry students. A mix of qualitative and quantitative research documents the efficacy of this approach for students and teachers. We conclude that mixed-reality learning is viable in mainstream high school classrooms and that students can achieve significant learning gains when this technology is co-designed with educators.

An Interactive Approach to Learning and Teaching in Visual Arts Education

ERIC Educational Resources Information Center

Tomljenovic, Zlata

2015-01-01

The present research focuses on modernising the approach to learning and teaching the visual arts in teaching practice, as well as examining the performance of an interactive approach to learning and teaching in visual arts classes with the use of a combination of general and specific (visual arts) teaching methods. The study uses quantitative…

Assessment of Superflux relative to marine science and oceanography. [airborne remote sensing of the Chesapeake Bay plume and shelf regions

NASA Technical Reports Server (NTRS)

Esaias, W. E.

1981-01-01

A general assessment of the Superflux project is made in relation to marine science and oceanography. It is commented that the program clearly demonstrated the effectiveness of state-of-the-art technology required to study highly dynamic estuarine plumes, and the necessity of a broadly interdisciplinary, interactive remote sensing and shipboard program required to significantly advance the understanding of transport processes and impacts of estuarine outflows.

In vitro fertilization (IVF)

MedlinePlus

IVF; Assisted reproductive technology; ART; Test-tube baby procedure; Infertility - in vitro ... conception. IVF is a form of assisted reproductive technology (ART). This means special medical techniques are used ...

Situated technology in reproductive health care: Do we need a new theory of the subject to promote person-centred care?

PubMed

Stankovic, Biljana

2017-01-01

Going through reproductive experiences (especially pregnancy and childbirth) in contemporary Western societies almost inevitably involves interaction with medical practitioners and various medical technologies in institutional context. This has important consequences for women as embodied subjects. A critical appraisal of these consequences-coming dominantly from feminist scholarship-relied on a problematic theory of both technology and the subject, which are in contemporary approaches no longer considered as given, coherent and well individualized wholes, but as complex constellations that are locally situated and that can only be described empirically. In this study, we will be relying on the developments in phenomenological theory to reconceptualize women as technologically mediated embodied subjects and on the new paradigms in philosophy of technology and STS to reconstruct medical technology as situated-with the aim of reconceptualizing their relationship and exploring different possibilities for the mediating role of medical technology. It will be argued that technologization of female reproductive processes and alienating consequences for women are not necessary or directly interrelated. The role of technology varies from case to case and depends mainly on the nontechnological and relational aspects of institutional context, in which medical practitioners play a decisive role. © 2016 John Wiley & Sons Ltd.

Evaluation of Distance Course Effectiveness - Exploring the Quality of Interactive Processes

NASA Astrophysics Data System (ADS)

Botelho, Francisco Villa Ulhôa; Vicari, Rosa Maria

Understanding the dynamics of learning processes implies an understanding of their components: individuals, environment or context and mediation. It is known that distance learning (DL) has a distinctive characteristic in relation to the mediation component. Due to the need of overcoming the barriers of distance and time, DL intensively uses information and communication technologies (ICT) to perform interactive processes. Construction of effective learning environments depends on human relationships. It also depends on the emotionality placed on such relationships. Therefore, knowing how to act in virtual environments in the sense of creating the required ambiance for animation of learning processes has a unique importance. This is the theme of this study. Its general objectives were achieved and can be summarized as follows: analyze indexes that are significant for evaluations of distance course effectiveness; investigate to which extent effectiveness of DL courses is correlated with quality of interactive processes; search characteristics of the conversations by individuals interacting in study groups that are formed in virtual environments, which may contribute to effectiveness of distance courses.

Enhancing User Experience through Emotional Interaction: Determining Users' Interests in Online Art Collections Using AMARA (Affective Museum of Art Resource Agent)

ERIC Educational Resources Information Center

Park, S. Joon

2013-01-01

The need for emotional interaction has already influenced various disciplines and industries, and online museums represent a domain where providing emotional interactions could have a significant impact. Today, online museums lack the appropriate affective and hedonic values necessary to engage art enthusiasts on an emotional level. To address…

Digital technology use among disadvantaged Australians: implications for equitable consumer participation in digitally-mediated communication and information exchange with health services.

PubMed

Newman, Lareen; Biedrzycki, Kate; Baum, Fran

2012-05-01

To present research findings on access to, and use of, digital information and communication technologies (ICTs) by Australians from lower income and disadvantaged backgrounds to determine implications for equitable consumer access to digitally-mediated health services and information. Focus groups were held in 2008-09 with 80 residents from lower income and disadvantaged backgrounds in South Australia, predominantly of working- and family-formation age (25 to 55 years). Qualitative analysis was conducted on a-priori and emergent themes to describe dominant categories. Access to, and use of, computers, the Internet and mobile phones varied considerably in extent, frequency and quality within and across groups due to differences in abilities, resources and life experience. Barriers and facilitators included English literacy (including for native speakers), technological literacy, education, income, housing situation, social connection, health status, employment status, and trust. Many people gained ICT skills by trial and error or help from friends, and only a few from formal programs, resulting in varied skills. The considerable variation in ICT access and use within lower income and disadvantaged groups must be acknowledged and accommodated by health initiatives and services when delivering digitally-mediated consumer-provider interaction, online health information, or online self-management of health conditions. If services require consumers to participate in a digitally-mediated communication exchange, then we suggest they might support skills and technology acquisition, or provide non-ICT alternatives, in order to avoid exacerbating health inequities.

Mozart to Michelangelo: Software to Hone Your Students' Fine Arts Skills.

ERIC Educational Resources Information Center

Smith, Russell

2000-01-01

Describes 15 art and music computer software products for classroom use. "Best bets" (mostly secondary level) include Clearvue Inc.'s Art of Seeing, Sunburst Technology's Curious George Paint & Print Studio, Inspiration Software's Inspiration 6.0, Harmonic Vision's Music Ace 2, and Coda Music Technology's PrintMusic! 2000 and SmartMusic Studio.…

Mechanisms for the Negative Effects of Internalized HIV-Related Stigma on Antiretroviral Therapy Adherence in Women: The Mediating Roles of Social Isolation and Depression.

PubMed

Turan, Bulent; Smith, Whitney; Cohen, Mardge H; Wilson, Tracey E; Adimora, Adaora A; Merenstein, Daniel; Adedimeji, Adebola; Wentz, Eryka L; Foster, Antonina G; Metsch, Lisa; Tien, Phyllis C; Weiser, Sheri D; Turan, Janet M

2016-06-01

Internalization of HIV-related stigma may inhibit a person's ability to manage HIV disease through adherence to treatment regimens. Studies, mainly with white men, have suggested an association between internalized stigma and suboptimal adherence to antiretroviral therapy (ART). However, there is a scarcity of research with women of different racial/ethnic backgrounds and on mediating mechanisms in the association between internalized stigma and ART adherence. The Women's Interagency HIV Study (WIHS) is a multicenter cohort study. Women living with HIV complete interviewer-administered questionnaires semiannually. Cross-sectional analyses for the current article included 1168 women on ART for whom data on medication adherence were available from their last study visit between April 2013 and March 2014, when the internalized stigma measure was initially introduced. The association between internalized stigma and self-reported suboptimal ART adherence was significant for those in racial/ethnic minority groups (AOR = 0.69, P = 0.009, 95% CI: 0.52 to 0.91), but not for non-Hispanic whites (AOR = 2.15, P = 0.19, 95% CI: 0.69 to 6.73). Depressive symptoms, loneliness, and low perceived social support mediated the association between internalized stigma and suboptimal adherence in the whole sample, as well as in the subsample of minority participants. In serial mediation models, internalized stigma predicted less-perceived social support (or higher loneliness), which in turn predicted more depressive symptoms, which in turn predicted suboptimal medication adherence. Findings suggest that interconnected psychosocial mechanisms affect ART adherence, and that improvements in adherence may require multifaceted interventions addressing both mental health and interpersonal factors, especially for minority women.

Mechanisms for the Negative Effects of Internalized HIV-Related Stigma on Antiretroviral Therapy Adherence in Women: The Mediating Roles of Social Isolation and Depression

PubMed Central

Smith, Whitney; Cohen, Mardge H.; Wilson, Tracey E.; Adimora, Adaora A.; Merenstein, Daniel; Adedimeji, Adebola; Wentz, Eryka L.; Foster, Antonina G.; Metsch, Lisa; Tien, Phyllis C.; Weiser, Sheri D.; Turan, Janet M.

2016-01-01

Background: Internalization of HIV-related stigma may inhibit a person's ability to manage HIV disease through adherence to treatment regimens. Studies, mainly with white men, have suggested an association between internalized stigma and suboptimal adherence to antiretroviral therapy (ART). However, there is a scarcity of research with women of different racial/ethnic backgrounds and on mediating mechanisms in the association between internalized stigma and ART adherence. Methods: The Women's Interagency HIV Study (WIHS) is a multicenter cohort study. Women living with HIV complete interviewer-administered questionnaires semiannually. Cross-sectional analyses for the current article included 1168 women on ART for whom data on medication adherence were available from their last study visit between April 2013 and March 2014, when the internalized stigma measure was initially introduced. Results: The association between internalized stigma and self-reported suboptimal ART adherence was significant for those in racial/ethnic minority groups (AOR = 0.69, P = 0.009, 95% CI: 0.52 to 0.91), but not for non-Hispanic whites (AOR = 2.15, P = 0.19, 95% CI: 0.69 to 6.73). Depressive symptoms, loneliness, and low perceived social support mediated the association between internalized stigma and suboptimal adherence in the whole sample, as well as in the subsample of minority participants. In serial mediation models, internalized stigma predicted less-perceived social support (or higher loneliness), which in turn predicted more depressive symptoms, which in turn predicted suboptimal medication adherence. Conclusions: Findings suggest that interconnected psychosocial mechanisms affect ART adherence, and that improvements in adherence may require multifaceted interventions addressing both mental health and interpersonal factors, especially for minority women. PMID:26885803

Advances in Maize Transformation Technologies and Development of Transgenic Maize

PubMed Central

Yadava, Pranjal; Abhishek, Alok; Singh, Reeva; Singh, Ishwar; Kaul, Tanushri; Pattanayak, Arunava; Agrawal, Pawan K.

2017-01-01

Maize is the principal grain crop of the world. It is also the crop where genetic engineering has been employed to a great extent to improve its various traits. The ability to transform maize is a crucial step for application of gene technology in maize improvement. There have been constant improvements in the maize transformation technologies over past several years. The choice of genotype and the explant material to initiate transformation and the different types of media to be used in various stages of tissue culture can have significant impact on the outcomes of the transformation efforts. Various methods of gene transfer, like the particle bombardment, protoplast transformation, Agrobacterium-mediated, in planta transformation, etc., have been tried and improved over years. Similarly, various selection systems for retrieval of the transformants have been attempted. The commercial success of maize transformation and transgenic development is unmatched by any other crop so far. Maize transformation with newer gene editing technologies is opening up a fresh dimension in transformation protocols and work-flows. This review captures the various past and recent facets in improvement in maize transformation technologies and attempts to present a comprehensive updated picture of the current state of the art in this area. PMID:28111576

Advances in Maize Transformation Technologies and Development of Transgenic Maize.

PubMed

Yadava, Pranjal; Abhishek, Alok; Singh, Reeva; Singh, Ishwar; Kaul, Tanushri; Pattanayak, Arunava; Agrawal, Pawan K

2016-01-01

Maize is the principal grain crop of the world. It is also the crop where genetic engineering has been employed to a great extent to improve its various traits. The ability to transform maize is a crucial step for application of gene technology in maize improvement. There have been constant improvements in the maize transformation technologies over past several years. The choice of genotype and the explant material to initiate transformation and the different types of media to be used in various stages of tissue culture can have significant impact on the outcomes of the transformation efforts. Various methods of gene transfer, like the particle bombardment, protoplast transformation, Agrobacterium -mediated, in planta transformation, etc., have been tried and improved over years. Similarly, various selection systems for retrieval of the transformants have been attempted. The commercial success of maize transformation and transgenic development is unmatched by any other crop so far. Maize transformation with newer gene editing technologies is opening up a fresh dimension in transformation protocols and work-flows. This review captures the various past and recent facets in improvement in maize transformation technologies and attempts to present a comprehensive updated picture of the current state of the art in this area.

What is art and how does it differ from aesthetics?

PubMed

Kreuzbauer, Robert

2017-01-01

Art objects differ from other objects because they are intentionally created to embody a producer's (i.e., artist's) expression. Hence, art objects are social objects whose appeal and value are determined largely by the strategic interaction between the artist and the audience. I discuss several aspects of how strategic interaction can affect an art object's perceived value and aesthetic appeal.

Art and Culture in the Space Age

NASA Astrophysics Data System (ADS)

Guidi, A.; de Chiara, V.

2002-01-01

The relation between culture and science it is a key point for understanding of our changing world. The relation between Art and Science needs to be analyzed more deeply and some specific field have to be studied with the help of people who really work in these field. One of the selected field will be certainly "theatre" one of the most ancient form of art and especially of communication. Since the Greek culture theatre contributed to diffuse culture, not only in the same community, but even in different one. Actors and their play were always travelling around. With the help of a director and of an actor in the paper will be described the argument from them point of view. Another fundamental art form is "Architecture". There is in the last period a strong changing in this field, the architecture is the form of art which is more related to technology. It can be said that Architecture can be considered as a "bridge" between Art and Technology. Finally even all the visual arts are strongly influenced by the nowadays technology. Different kind of visual arts will be considered, and impressions from people working on them will be analysed. An other aspect of our changing world is the evolution of the communication and the diffusion of culture, through century. This aspect and the nowadays level of "communication technology" is another key point who will be further analyzed. Conclusion is identified in opening the door to a wider variety of experiments on the International Space Station (ISS). A type of experiments devoted to involve a wider number of people in space technology. A type of experiments which will also bring the space age closer to a public that has least interest in technical fields. This increase of public support will bring to the space technology an increase in development. The more public interest there is in a certain technology, the larger it is its development. Finally this type of experiments would also open sociological and psychological study.

Longitudinal Analysis of Music Education on Executive Functions in Primary School Children

PubMed Central

Jaschke, Artur C.; Honing, Henkjan; Scherder, Erik J. A.

2018-01-01

Background: Research on the effects of music education on cognitive abilities has generated increasing interest across the scientific community. Nonetheless, longitudinal studies investigating the effects of structured music education on cognitive sub-functions are still rare. Prime candidates for investigating a relationship between academic achievement and music education appear to be executive functions such as planning, working memory, and inhibition. Methods: One hundred and forty-seven primary school children, Mage = 6.4 years, SD = 0.65 were followed for 2.5 years. Participants were randomized into four groups: two music intervention groups, one active visual arts group, and a no arts control group. Neuropsychological tests assessed verbal intelligence and executive functions. Additionally, a national pupil monitor provided data on academic performance. Results: Children in the visual arts group perform better on visuospatial memory tasks as compared to the three other conditions. However, the test scores on inhibition, planning and verbal intelligence increased significantly in the two music groups over time as compared to the visual art and no arts controls. Mediation analysis with executive functions and verbal IQ as mediator for academic performance have shown a possible far transfer effect from executive sub-function to academic performance scores. Discussion: The present results indicate a positive influence of long-term music education on cognitive abilities such as inhibition and planning. Of note, following a two-and-a-half year long visual arts program significantly improves scores on a visuospatial memory task. All results combined, this study supports a far transfer effect from music education to academic achievement mediated by executive sub-functions. PMID:29541017

Longitudinal Analysis of Music Education on Executive Functions in Primary School Children.

PubMed

Jaschke, Artur C; Honing, Henkjan; Scherder, Erik J A

2018-01-01

Background: Research on the effects of music education on cognitive abilities has generated increasing interest across the scientific community. Nonetheless, longitudinal studies investigating the effects of structured music education on cognitive sub-functions are still rare. Prime candidates for investigating a relationship between academic achievement and music education appear to be executive functions such as planning, working memory, and inhibition. Methods: One hundred and forty-seven primary school children, M age = 6.4 years, SD = 0.65 were followed for 2.5 years. Participants were randomized into four groups: two music intervention groups, one active visual arts group, and a no arts control group. Neuropsychological tests assessed verbal intelligence and executive functions. Additionally, a national pupil monitor provided data on academic performance. Results: Children in the visual arts group perform better on visuospatial memory tasks as compared to the three other conditions. However, the test scores on inhibition, planning and verbal intelligence increased significantly in the two music groups over time as compared to the visual art and no arts controls. Mediation analysis with executive functions and verbal IQ as mediator for academic performance have shown a possible far transfer effect from executive sub-function to academic performance scores. Discussion: The present results indicate a positive influence of long-term music education on cognitive abilities such as inhibition and planning. Of note, following a two-and-a-half year long visual arts program significantly improves scores on a visuospatial memory task. All results combined, this study supports a far transfer effect from music education to academic achievement mediated by executive sub-functions.

Micro- and nanodevices integrated with biomolecular probes

PubMed Central

Alapan, Yunus; Icoz, Kutay; Gurkan, Umut A.

2016-01-01

Understanding how biomolecules, proteins and cells interact with their surroundings and other biological entities has become the fundamental design criterion for most biomedical micro- and nanodevices. Advances in biology, medicine, and nanofabrication technologies complement each other and allow us to engineer new tools based on biomolecules utilized as probes. Engineered micro/nanosystems and biomolecules in nature have remarkably robust compatibility in terms of function, size, and physical properties. This article presents the state of the art in micro- and nanoscale devices designed and fabricated with biomolecular probes as their vital constituents. General design and fabrication concepts are presented and three major platform technologies are highlighted: microcantilevers, micro/nanopillars, and microfluidics. Overview of each technology, typical fabrication details, and application areas are presented by emphasizing significant achievements, current challenges, and future opportunities. PMID:26363089

Communication technology use and mHealth acceptance among HIV-infected men who have sex with men in Peru: implications for HIV prevention and treatment.

PubMed

Krishnan, Archana; Ferro, Enrico G; Weikum, Damian; Vagenas, Panagiotis; Lama, Javier R; Sanchez, Jorge; Altice, Frederick L

2015-01-01

The HIV epidemic in Peru is concentrated among men who have sex with men (MSM). Given that MSM have been documented as early adopters of emerging technology, we examined communication technology access and utilization, and mobile health (mHealth) acceptance among Peruvian MSM and transgender women (TGW) in order to gauge opportunities for mHealth-enabled HIV interventions. A convenience sample of 359 HIV-infected MSM and TGW recruited from three sites in Lima, Peru completed standardized assessments of alcohol use disorders (AUDs), risky sexual behavior, and antiretroviral therapy (ART) adherence along with self-constructed measures of communication technology access and utilization, and mHealth acceptance. Most participants (86%) had daily access to any cell phone, including smartphones (30%). The most frequent communication activities were receiving and making calls, and receiving and sending text messages using cell phones. On a 5-point Likert scale, participants expressed interest in using mHealth for medication reminders (M = 3.21, SD = 1.32) and engaging in anonymous online interactions with health professionals to discuss HIV-related issues (M = 3.56, SD = 1.33). Importantly, no significant differences were found in communication technology use and mHealth acceptance among participants with AUDs, depression, and suboptimal ART adherence, all of which are associated with poor HIV treatment outcomes. Findings show support for implementing mHealth-based intervention strategies using cell phones to assess and reduce HIV-risk behaviors among HIV-infected MSM and TGW.

My First CMC Article Revisited: A Window on Spanish L2 Interlanguage

ERIC Educational Resources Information Center

Blake, Robert

2016-01-01

The computer-assisted language learning (CALL) field seems to change overnight with new technological affordances. Blake revisits his 2000 "LLT" article on computer-mediation communication (CMC) in order to reflect on how the field has examined this topic over the past decade or so. While the Interaction Hypothesis continues to guide…

Keep Your Eye on the Prize: Implementing AAC within the Broader Context of Communicative Competence

ERIC Educational Resources Information Center

DeThorne, Laura Segebart; Hengst, Julie; Fisher, Kim; King, Amie

2014-01-01

Electronic technologies are playing an increasing role in mediating patterns of social interaction within the classroom. This trend includes augmentative and alternative communication (AAC) systems like light-weight smart tablets. AAC in general has proven effective for many children in regard to decreasing challenging behavior, enabling…

Appropriation of a Representational Tool in a Second-Language Classroom

ERIC Educational Resources Information Center

Wen, Yun; Looi, Chee-Kit; Chen, Wenli

2015-01-01

While the affordances of face-to-face and online environments have been studied somewhat extensively, there is relatively less research on how technology-mediated learning takes place across multiple media in the networked classroom environment where face-to-face and online interactions are intertwined, especially in the context of language…

Social Presence Reconsidered: Moving Beyond, Going Back, or Killing Social Presence

ERIC Educational Resources Information Center

Öztok, Murat; Kehrwald, Benjamin A.

2017-01-01

Online education research has long employed the concept of social presence to study interactions in technologically mediated spaces. Yet, a precise shared definition of social presence does not exist. This article traces how the concept of social presence has been developed and appropriated in the online and distance education literature. We do…

Kindergarten Teachers' Orchestration of Mathematical Activities Afforded by Technology: Agency and Mediation

ERIC Educational Resources Information Center

Carlsen, Martin; Erfjord, Ingvald; Hundeland, Per Sigurd; Monaghan, John

2016-01-01

This paper focuses on kindergarten teachers' interactions with young children during mathematical learning activities involving the use of digital tools. We aim to characterise the teachers' roles and actions in these activities and extend considerations of teachers' orchestrations current in the research literature with regard to agency and…

Visible Korean human images on MIOS system

NASA Astrophysics Data System (ADS)

Har, Donghwan; Son, Young-Ho; Lee, Sung-Won; Lee, Jung Beom

2004-05-01

Basically, photography has the attributes of reason, which encompasses the scientific knowledge of optics, physics and chemistry, and delicate sensibility of individuals. Ultimately, the photograph pursues "effective communication." Communication is "mental and psychosocial exchange mediated by material symbols, such as language, gesture and picture," and it has four compositions: "sender, receiver, message and channel." Recently, a change in the communication method is on the rise in the field of art and culture, including photography. Until now, communication was mainly achieved by the form of messages unilaterally transferred from senders to receivers. But, nowadays, an interactive method, in which the boundary of sender and receiver is obscure, is on the increase. Such new communication method may be said to have arrived from the desire of art and culture societies, pursuing something new and creative in the background of utilization of a variety of information media. The multi-view screen we developed is also a communication tool capable of effective interaction using photos or motion pictures. The viewer can see different images at different locations. It utilizes the basic lenticular characteristics, which have been used in printing. Each motion picture is displayed on the screen without crosstalk. The multi-view screen is different in many aspects from other display media, and is expected to be utilized in many fields, including advertisement, display and education.

A novel computerized surgeon-machine interface for robot-assisted laser phonomicrosurgery.

PubMed

Mattos, Leonardo S; Deshpande, Nikhil; Barresi, Giacinto; Guastini, Luca; Peretti, Giorgio

2014-08-01

To introduce a novel computerized surgical system for improved usability, intuitiveness, accuracy, and controllability in robot-assisted laser phonomicrosurgery. Pilot technology assessment. The novel system was developed involving a newly designed motorized laser micromanipulator, a touch-screen display, and a graphics stylus. The system allows the control of a CO2 laser through interaction between the stylus and the live video of the surgical area. This empowers the stylus with the ability to have actual effect on the surgical site. Surgical enhancements afforded by this system were established through a pilot technology assessment using randomized trials comparing its performance with a state-of-the-art laser microsurgery system. Resident surgeons and medical students were chosen as subjects in performing sets of trajectory-following exercises. Image processing-based techniques were used for an objective performance assessment. A System Usability Scale-based questionnaire was used for the qualitative assessment. The computerized interface demonstrated superiority in usability, accuracy, and controllability over the state-of-the-art system. Significant ease of use and learning experienced by the subjects were demonstrated by the usability score assigned to the two compared interfaces: computerized interface = 83.96% versus state-of-the-art = 68.02%. The objective analysis showed a significant enhancement in accuracy and controllability: computerized interface = 90.02% versus state-of-the-art = 75.59%. The novel system significantly enhances the accuracy, usability, and controllability in laser phonomicrosurgery. The design provides an opportunity to improve the ergonomics and safety of current surgical setups. © 2014 The American Laryngological, Rhinological and Otological Society, Inc.

Investigation of Personality Traits between Infertile Women Submitted to Assisted Reproductive Technology or Surrogacy

PubMed Central

Asgari, Najmeh; Yazdkhasti, Fariba; Nasr Esfahani, Mohammad Hossein

2016-01-01

Background Personality traits affect human relationships, social interactions, treatment procedures, and essentially all human activities. The purpose of this study is to investigate the personality traitsincluding sensation seeking, flexibility, and happiness among a variety of infertile women who were apt to choose assisted reproductive technology (ART) or surrogacy. Materials and Methods This is a cross-sectional study that was performed on 251 infertile women who visited Isfahan and Tehran Reproductive Medicine Center. These fertility clinics are located in Isfahan and Tehran, Iran. In this study, 201 infertile women who underwent treatment using ART and 50 infertile women who tended to have surrogacy were chosen by convenience sampling. Zuckerman’s Sensation Seeking Scale Form V (SSS-V), Psychological Flexibility Questionnaire (adapted from NEO Personality Inventory-Revised) and Oxford Happiness Questionnaire (OHQ) were used as research instruments. All participants had to complete the research instruments in order to be included in this study. Data were analyzed by descriptive-analytical statistics and statistical tests including multivariate analysis of variance (MANOVA) and Z Fisher. Statistically significant effects were accepted for P<0.05. Results In the sensation-seeking variable, there was a meaningful difference between under-study groups. However, the flexibility and happiness variables did not have a significant difference between under-study groups (P<0.001). Interaction between education, employment, and financial status was effective in happiness of infertile women underwent ART (P<0.05), while age, education and financial status were also effective in happiness of infertile women sought surrogacy (P<0.05). A positive meaningful relationship was seen between sensation seeking and flexibility variables in both groups (P<0.05). And a negative meaningful relationship was seen between sensation seeking and happiness in infertile women who sought surrogacy (P<0.05). The difference in rate of relationship between sensation seeking and flexibility was meaningful in infertile women who sought either ART or surrogacy (P<0.05). Conclusion Sensations seeking as a personality trait is lower in infertile women who underwent treatment using ART compared women who tended to have surrogacy. This study shows that demographic variables are effective in happiness of infertile women. Also, there is a significant relation among sensation seeking, flexibility and happiness in infertile women. PMID:27123206

The Babushka Project: Mediating between the Margins and Wider Community through Public Art Creation

ERIC Educational Resources Information Center

Gray, Bronwen Lucie

2012-01-01

This article discusses the theoretical and social contexts of a community art project that took place at a public housing estate located in Melbourne, Australia. The art intervention was aimed at increasing the residents' health and well-being through the empowerment of their own cultural creations. Three sculptures in the form of giant babushka…

Oligonucleotide Aptamers: New Tools for Targeted Cancer Therapy

PubMed Central

Sun, Hongguang; Zhu, Xun; Lu, Patrick Y; Rosato, Roberto R; Tan, Wen; Zu, Youli

2014-01-01

Aptamers are a class of small nucleic acid ligands that are composed of RNA or single-stranded DNA oligonucleotides and have high specificity and affinity for their targets. Similar to antibodies, aptamers interact with their targets by recognizing a specific three-dimensional structure and are thus termed “chemical antibodies.” In contrast to protein antibodies, aptamers offer unique chemical and biological characteristics based on their oligonucleotide properties. Hence, they are more suitable for the development of novel clinical applications. Aptamer technology has been widely investigated in various biomedical fields for biomarker discovery, in vitro diagnosis, in vivo imaging, and targeted therapy. This review will discuss the potential applications of aptamer technology as a new tool for targeted cancer therapy with emphasis on the development of aptamers that are able to specifically target cell surface biomarkers. Additionally, we will describe several approaches for the use of aptamers in targeted therapeutics, including aptamer-drug conjugation, aptamer-nanoparticle conjugation, aptamer-mediated targeted gene therapy, aptamer-mediated immunotherapy, and aptamer-mediated biotherapy. PMID:25093706

Using a Networked Mac Lab To Facilitate Learning in Art, Foreign Languages, and English.

ERIC Educational Resources Information Center

Brutchin, Patricia; And Others

These presentations examine the use of a new Macintosh Lab in Commercial Art Technology, Spanish, and English Composition classes at Clark State Community College. The first paper describes the Commercial Art Technology program at the college, highlighting the use of the Mac Lab installed in September 1993 and discussing the Electronic Publishing,…

Parent-Child Moments of Meeting in Art-Making with Collage, iPad, Tuxpaint and Crayons

ERIC Educational Resources Information Center

Sakr, Mona; Kucirkova, Natalia

2017-01-01

Previous research suggests that parent-child art making can foster opportunities for closeness between children and parents. Most studies however, have focused on art-making that involves paint and paper, or non-digital drawing technologies. There is a need for researchers to consider how a wider range of technologies, including digital…

Promising Practices in Higher Education: Art Education and Human Rights Using Information, Communication Technologies (ICT)

ERIC Educational Resources Information Center

Black, Joanna; Cap, Orest

2014-01-01

Promising pedagogical practices is described in relation to incorporating ICT (Information, Communication and Technologies) with the study of Human Rights issues in Visual Arts Education for teacher candidates. As part of a course, "Senior Years Art," students at the Faculty of Education, University of Manitoba during 2013-2014…

INNOVATIVE TECHNOLOGY EVALUATION REPORT, SEDIMENT SAMPLING TECHNOLOGY, ART'S MANUFACTURING, SPLIT CORE SAMPLER FOR SUBMERGED SEDIMENTS

EPA Science Inventory

The Split Core Sampler for Submerged Sediments (Split Core Sampler) designed and fabricated by Arts Manufacturing & Supply, Inc., was demonstrated under the U.S. Environmental Protection Agency (EPA) Superfund Innovative Technology Evaluation Program in April and May 1999 at ...

Are "Wii" Exercising Correctly? Understanding How Exergames Can Be Used to Increase Knowledge of Exercise Behavior.

PubMed

Limperos, Anthony M

2014-02-01

Many studies have investigated how commercial exergames can be used to increase physical activity and energy expenditure, but relatively few have focused on understanding if these games can impact learning of exercise behavior. The objective of this research is to understand how features of mediated exercise technologies can impact learning of exercise behavior. One hundred thirty college students (mean age, 20.56 years old) participated in a between-subjects experiment where they spent approximately 10 minutes exercising with either the "Biggest Loser" exergame (for the Nintendo(®) [Redmond, WA] Wii™ console) or the Biggest Loser Workout Vol. 2 DVD. Then, participants filled out a questionnaire with items pertaining to interactivity, trainer liking, self-efficacy, and learning. Analysis of covariance tests and meditational analyses were used to answer the questions of interest. Results indicated that participants who interacted with an exergame experienced greater interactivity and learning from playing the game than working out with the nearly identical exercise DVD. Furthermore, the relationship between playing an exergame and learning was mediated by interactivity. This study suggests that exergames may be more beneficial than similar mediated exercise companions in encouraging learning about exercise. Theoretical and practical implications as well as limitations and future research considerations are discussed.

Two cultures are better than one: Earth sciences and Art for a better planet sustainability

NASA Astrophysics Data System (ADS)

Lanza, Tiziana; Rubbia, Giuliana; Negrete, Aquiles

2015-04-01

Climate change, pollution, desertification, natural hazard, animals' extinction are some of the problems we face every day. Very often Science and Technology are charged of the solutions while Art is intended mainly for entertainment. Are we sure this is the right attitude? "Technology is a queer thing. It brings you gifts with one hand, and stabs you in the back with the other", says C.P.Snow, author of a milestone book on the Two Cultures, namely Sciences and Humanities. If Science can drive to a rigorous knowledge of the Earth speaking to people's mind, Technology is Science in action. When individuals act very often the reasons behind their actions are linked to their education, values, sense of beauty, presence or absence of feelings, all things pertaining to the emotional sphere of humans usually addressed by humanistic culture. But if in one hand, Science and Technology cannot be left alone to solve the impelling problems that are deteriorating not only our planet resources but also our quality of life, on the other hand the humanistic culture can find a powerful ally in scientific culture for re-awakening in everybody the sense of beauty, values and respect for the planet. To know Earth is to love Earth, since nature is in itself a work of Art. Earth sciences dig out all the secrets that make our planet a unique place in the Universe we know. Every single phenomena can be seen then in a double face value. An Aurora, for instance, can inspire poetry for its beauty and colors but always remains the result of the interaction between the solar wind and the Earth magnetic field. And, most important, an Aurora will never inspire negative feelings. To make our part in creating a common field between Art and Earth sciences, we have created a blog and a related FaceBook page to collect, browsing the web, all the experiences in this trend, to find out that many scientists and artists are already working in this direction as a final and enjoyable surprise.

Nanoparticle puzzles and research opportunities that go beyond state of the art.

PubMed

Jee, Ah-Young; Lou, Kai; Jang, Hyun-Sook; Nagamanasa, K Hima; Granick, Steve

2016-01-01

We present an overview of current progress and research challenges in the field of nanoparticle assembly, touching on the following topics: (1) historical perspective; (2) consideration of what is a nanoparticle; (3) contrast between nanoparticle self-assembly and top-down construction; (4) opportunities for nanoparticles with more intelligent sub-structures; (5) opportunities for nanoparticle systems cued to interact subtly in space and time. In this personal and subjective account, certain holy grails for nanoparticle science and technology are identified.

Effectiveness of Artistic Interaction through Video Conferencing

ERIC Educational Resources Information Center

Eristi, Suzan Duygu

2011-01-01

This study investigated Turkish and Canadian primary school students' ways of expressing their perception of interactive art education through video conferencing and that of cultural interaction through pictorial representations. The qualitative research data were collected in the form of pictures and interviews on interactive art education along…

Forty and 80 GHz technology assessment and forecast including executive summary

NASA Technical Reports Server (NTRS)

Mazur, D. G.; Mackey, R. J., Jr.; Tanner, S. G.; Altman, F. J.; Nicholas, J. J., Jr.; Duchaine, K. A.

1976-01-01

The results of a survey to determine current demand and to forecast growth in demand for use of the 40 and 80 GHz bands during the 1980-2000 time period are given. The current state-of-the-art is presented, as well as the technology requirements of current and projected services. Potential developments were identified, and a forecast is made. The impacts of atmospheric attenuation in the 40 and 80 GHz bands were estimated for both with and without diversity. Three services for the 1980-2000 time period -- interactive television, high quality three stereo pair audio, and 30 MB data -- are given with system requirements and up and down-link calculations.

Fluorescence imaging host pathogen interactions: fifteen years benefit of hindsight….

PubMed

Aulner, Nathalie; Danckaert, Anne; Fernandes, Julien; Nicola, Marie-Anne; Roux, Pascal; Salles, Audrey; Tinevez, Jean-Yves; Shorte, Spencer L

2018-03-19

We consider in review current state-of-the-art fluorescence microscopy for investigating the host-pathogen interface. Our perspective is honed from years with literally thousands of microbiologists using the variety of imaging technologies available within our dedicated BSL2/BSL3 optical imaging research service facilities at the Institut Pasteur Paris founded from scratch in 2001. During fifteen years learning from the success and failures of introducing different fluorescence imaging technologies, methods, and technical development strategies we provide here a synopsis review of our experience to date and a synthesis of how we see the future in perspective for fluorescence imaging at the host-pathogen interface. Copyright © 2018. Published by Elsevier Ltd.

Reading, Language Arts and Literacy. [SITE 2002 Section].

ERIC Educational Resources Information Center

Matthew, Kathy, Ed.

This document contains the following papers on reading, language arts, and literacy from the SITE (Society for Information Technology & Teacher Education) 2002 conference: "PT3 Facilitates Technology Use in Preservice Teacher Reading Courses" (Dana Arrowood and Michele Maldonado); "PT3 Technology Enhanced Lesson Plans for the Elementary School"…

The Relationship between Psychological Type and Professional Orientation among Technology Education Teachers.

ERIC Educational Resources Information Center

Wicklein, Robert C.; Rojewski, Jay W.

1995-01-01

Of secondary school teachers who completed the Keirsey-Bates Temperament Sorter, 136 were in technology education, 110 in industrial arts. Two types were prevalent among industrial arts teachers: Extrovert Sensing Feeling Judging and Introvert Sensing Feeling Judging. Technology education teachers were more Extrovert Intuitive Thinking Judging,…

Rethinking radical politics in the context of assisted reproductive technology.

PubMed

Parks, Jennifer

2009-01-01

Radical feminists have argued for both the radical potential of assisted reproductive technology (ART) and its oppressive and damaging effects for women. This paper will address the question of what constitutes a radical feminist position on ART; I will argue that the very debate over whether ART liberates or oppresses women is misguided, and that instead the issue should be understood dialectically. Reproductive technologies are neither inherently liberating nor entirely oppressive: we can only understand the potential and effects by considering how they are actually taken up within a culture. The internal contradictions, tensions, and inconsistencies within ART and the way it is addressed within the law points to a dialectic that resists a simple reductivist understanding.

Control/structure interaction design methodology

NASA Technical Reports Server (NTRS)

Briggs, Hugh C.; Layman, William E.

1989-01-01

The Control Structure Interaction Program is a technology development program for spacecraft that exhibit interactions between the control system and structural dynamics. The program objectives include development and verification of new design concepts (such as active structure) and new tools (such as a combined structure and control optimization algorithm) and their verification in ground and possibly flight test. The new CSI design methodology is centered around interdisciplinary engineers using new tools that closely integrate structures and controls. Verification is an important CSI theme and analysts will be closely integrated to the CSI Test Bed laboratory. Components, concepts, tools and algorithms will be developed and tested in the lab and in future Shuttle-based flight experiments. The design methodology is summarized in block diagrams depicting the evolution of a spacecraft design and descriptions of analytical capabilities used in the process. The multiyear JPL CSI implementation plan is described along with the essentials of several new tools. A distributed network of computation servers and workstations was designed that will provide a state-of-the-art development base for the CSI technologies.

Mood Swings: An Affective Interactive Art System

NASA Astrophysics Data System (ADS)

Bialoskorski, Leticia S. S.; Westerink, Joyce H. D. M.; van den Broek, Egon L.

The progress in the field of affective computing enables the realization of affective consumer products, affective games, and affective art. This paper describes the affective interactive art system Mood Swings, which interprets and visualizes affect expressed by a person. Mood Swings is founded on the integration of a framework for affective movements and a color model. This enables Mood Swings to recognize affective movement characteristics as expressed by a person and display a color that matches the expressed emotion. With that, a unique interactive system is introduced, which can be considered as art, a game, or a combination of both.

From art to applied science.

PubMed

Schatzberg, Eric

2012-09-01

Before "applied science" and "technology" became keywords, the concept of art was central to discourse about material culture and its connections to natural knowledge. By the late nineteenth century, a new discourse of applied science had replaced the older discourse of art. This older discourse of art, especially as presented in Enlightenment encyclopedias, addressed the relationship between art and science in depth. But during the nineteenth century the concept of fine art gradually displaced the broader meanings of "art," thus undermining the utility of the term for discourse on the relationship between knowledge and practice. This narrowed meaning of "art" obscured key aspects of the industrial world. In effect, middle-class agents of industrialism, including "men of science," used the rhetoric of "applied science" and, later, "technology" to cement the exclusion of artisanal knowledge from the discourse of industrial modernity.

Adverse pregnancy and birth outcomes associated with underlying diagnosis with and without assisted reproductive technology treatment.

PubMed

Stern, Judy E; Luke, Barbara; Tobias, Michael; Gopal, Daksha; Hornstein, Mark D; Diop, Hafsatou

2015-06-01

To compare the risks for adverse pregnancy and birth outcomes by diagnoses with and without assisted reproductive technology (ART) treatment to non-ART pregnancies in fertile women. Historical cohort of Massachusetts vital records linked to ART clinic data from Society for Assisted Reproductive Technology Clinic Outcome Reporting System. Not applicable. Diagnoses included male factor (ART only), endometriosis, ovulation disorders, tubal (ART only), and reproductive inflammatory disorders (non-ART only). Pregnancies resulting in singleton and twin live births from 2004 to 2008 were linked to hospital discharges in women who had ART treatment (n = 3,689), women with no ART treatment in the current pregnancy (n = 4,098), and non-ART pregnancies in fertile women (n = 297,987). None. Risks of gestational diabetes, prenatal hospitalizations, prematurity, low birth weight, and small for gestational age were modeled using multivariate logistic regression with fertile deliveries as the reference group adjusted for maternal age, race/ethnicity, education, chronic hypertension, diabetes mellitus, and plurality (adjusted odds ratios [AORs] and 95% confidence intervals [CIs]). Risk of prenatal hospital admissions was increased for endometriosis (ART: 1.97, 1.38-2.80; non-ART: 3.34, 2.59-4.31), ovulation disorders (ART: 2.31, 1.81-2.96; non-ART: 2.56, 2.05-3.21), tubal factor (ART: 1.51, 1.14-2.01), and reproductive inflammation (non-ART: 2.79, 2.47-3.15). Gestational diabetes was increased for women with ovulation disorders (ART: 2.17, 1.72-2.73; non-ART: 1.94, 1.52-2.48). Preterm delivery (AORs, 1.24-1.93) and low birth weight (AORs, 1.27-1.60) were increased in all groups except in endometriosis with ART. The findings indicate substantial excess perinatal morbidities associated with underlying infertility-related diagnoses in both ART-treated and non-ART-treated women. Copyright © 2015 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Mediator, SWI/SNF and SAGA complexes regulate Yap8-dependent transcriptional activation of ACR2 in response to arsenate.

PubMed

Menezes, Regina Andrade; Pimentel, Catarina; Silva, Ana Rita Courelas; Amaral, Catarina; Merhej, Jawad; Devaux, Frédéric; Rodrigues-Pousada, Claudina

2017-04-01

Response to arsenic stress in Saccharomyces cerevisiae is orchestrated by the regulatory protein Yap8, which mediates transcriptional activation of ACR2 and ACR3. This study contributes to the state of art knowledge of the molecular mechanisms underlying yeast stress response to arsenate as it provides the genetic and biochemical evidences that Yap8, through cysteine residues 132, 137, and 274, is the sensor of presence of arsenate in the cytosol. Moreover, it is here reported for the first time the essential role of the Mediator complex in the transcriptional activation of ACR2 by Yap8. Based on our data, we propose an order-of-function map to recapitulate the sequence of events taking place in cells injured with arsenate. Modification of the sulfhydryl state of these cysteines converts Yap8 in its activated form, triggering the recruitment of the Mediator complex to the ACR2/ACR3 promoter, through the interaction with the tail subunit Med2. The Mediator complex then transfers the regulatory signals conveyed by Yap8 to the core transcriptional machinery, which culminates with TBP occupancy, ACR2 upregulation and cell adaptation to arsenate stress. Additional co-factors are required for the transcriptional activation of ACR2 by Yap8, particularly the nucleosome remodeling activity of SWI/SNF and SAGA complexes. Copyright © 2017. Published by Elsevier B.V.

Smart Data Infrastructure: The Sixth Generation of Mediation for Data Science

NASA Astrophysics Data System (ADS)

Fox, P. A.

2014-12-01

In the emergent "fourth paradigm" (data-driven) science, the scientific method is enhanced by the integration of significant data sources into the practice of scientific research. To address Big Science, there are challenges in understanding the role of data in enabling researchers to attack not just disciplinary issues, but also the system-level, large-scale, and transdisciplinary global scientific challenges facing society.Recognizing that the volume of data is only one of many dimensions to be considered, there is a clear need for improved data infrastructures to mediate data and information exchange, which we contend will need to be powered by semantic technologies. One clear need is to provide computational approaches for researchers to discover appropriate data resources, rapidly integrate data collections from heterogeneously resources or multiple data sets, and inter-compare results to allow generation and validation of hypotheses. Another trend is toward automated tools that allow researchers to better find and reuse data that they currently don't know they need, let alone know how to find. Again semantic technologies will be required. Finally, to turn data analytics from "art to science", technical solutions are needed for cross-dataset validation, reproducibility studies on data-driven results, and the concomitant citation of data products allowing recognition for those who curate and share important data resources.

A Junior High School Industrial Technology Curriculum Project: A Final Evaluation of the Industrial Arts Curriculum Project (IACP), 1965-1971.

ERIC Educational Resources Information Center

Buffer, James J.; And Others

The objective of the Industrial Arts Curriculum Project (IACP) was to develop, refine, and institutionalize a new and relevant 2-year junior high industrial arts program. The study focused on "industrial technology," the knowledge of management, production, and personnel practices used by men to produce goods to satisfy their needs…

Integrating On-Line Technology into Teaching Activities to Enhance Student and Teacher Learning in a New Zealand Primary School

ERIC Educational Resources Information Center

Baskerville, Delia

2012-01-01

Continuing emphasis given to computer technology resourcing in schools presents potential for web-based initiatives which focus on quality arts teaching and learning, as ways to improve arts outcomes for all students. An arts e-learning collaborative research project between specialist on-line teacher/researchers and generalist primary teachers…

Training in reproductive endocrinology and infertility and assisted reproductive technologies: options and worldwide needs.

PubMed

de Ziegler, Dominique; de Ziegler, Nathalie; Sean, Sokteang; Bajouh, Osama; Meldrum, David R

2015-07-01

Standardized, high-quality training in reproductive endocrinology, infertility, and assisted reproductive technologies (REI-ART) faces challenges owing to the high-tech nature of ART and the important country-to-country differences in clinical practice and regulations overseeing training. Moreover, while the training capacity of the classical by-fellowship training platforms is shrinking, an increasing demand for REI-ART specialists is coming from emerging countries. To meet this expanding need for REI-ART specialists, we propose a novel by-network model linking a reference training center to satellite practical training sites. Simulation should be used more extensively to achieve competency before initiating live clinical experience, analogous to the highly effective training systems that have been used in aviation for decades. Large ART databases that exist because of obligations to report ART activity and results constitute unique yet so far untapped sources for developing by-scenario simulation training models. Online training materials incorporating these state-of-the-art information technology tools could be developed as a means of fulfilling training needs worldwide. Copyright © 2015. Published by Elsevier Inc.

The Effect of Active Creation on Psychological Health: A Feasibility Study on (Therapeutic) Mechanisms

PubMed Central

Lange, Gudrun; Leonhart, Rainer; Gruber, Harald

2018-01-01

Creation is an important part of many interventions in creative arts therapies (art, music, dance, and drama therapy). This active part of art-making in arts therapies has not yet been closely investigated. The present study commits to this field of research using a mixed-methods design to investigate the effects of active creation on health-related psychological outcomes. In an artistic inquiry within an experimental design, N = 44 participants engaged in active art-making for eight minutes in the presence of the researcher (first author) with a choice of artistic materials: paper and colors for drawing and writing, musical instruments, space for moving or performing. Before and after the creation, participants completed a well-being, a self-efficacy and an experience of creation scale, and in addition found their own words to express the experiences during the activity. We hypothesized that the experience of empowerment, freedom, impact, and creativity (Experience of Creation Scale) mediates the positive effect of active creation on the outcomes of self-efficacy and well-being, and evaluated this assumption with a mediation analysis. Results suggest that the effect of active creation on both self-efficacy and well-being is significantly mediated by the Experience of Creation Scale. This article focuses on the quantitative side of the investigation. During the process, qualitative and quantitative results were triangulated for a more valid evaluation and jointly contribute to the emerging theory frame of embodied aesthetics. PMID:29439541

The Effect of Active Creation on Psychological Health: A Feasibility Study on (Therapeutic) Mechanisms.

PubMed

Lange, Gudrun; Leonhart, Rainer; Gruber, Harald; Koch, Sabine C

2018-02-12

Creation is an important part of many interventions in creative arts therapies (art, music, dance, and drama therapy). This active part of art-making in arts therapies has not yet been closely investigated. The present study commits to this field of research using a mixed-methods design to investigate the effects of active creation on health-related psychological outcomes. In an artistic inquiry within an experimental design, N = 44 participants engaged in active art-making for eight minutes in the presence of the researcher (first author) with a choice of artistic materials: paper and colors for drawing and writing, musical instruments, space for moving or performing. Before and after the creation, participants completed a well-being, a self-efficacy and an experience of creation scale, and in addition found their own words to express the experiences during the activity. We hypothesized that the experience of empowerment, freedom, impact, and creativity (Experience of Creation Scale) mediates the positive effect of active creation on the outcomes of self-efficacy and well-being, and evaluated this assumption with a mediation analysis. Results suggest that the effect of active creation on both self-efficacy and well-being is significantly mediated by the Experience of Creation Scale. This article focuses on the quantitative side of the investigation. During the process, qualitative and quantitative results were triangulated for a more valid evaluation and jointly contribute to the emerging theory frame of embodied aesthetics.

Imaging host-Leishmania interactions: significance in visceral leishmaniasis.

PubMed

Forestier, C-L

2013-01-01

Leishmaniasis is a neglected disease that is associated with a spectrum of clinical manifestations ranging from self-healing cutaneous lesions to fatal visceral infections, which primarily depends on the parasite species. In visceral leishmaniasis (VL), as opposed to cutaneous leishmaniasis (CL), parasites that infect host cells at the sand fly bite site have the striking ability to disseminate to visceral organs where they proliferate and persist for long periods of time. Imaging the dynamics of the host-Leishmania interaction in VL provides a powerful approach to understanding the mechanisms underlying host cell invasion, Leishmania dissemination and persistence within visceral organs and, to dissecting the immune responses to infection. Therefore, by allowing the visualization of the critical steps involved in the pathogenesis of VL, state-of-the-art microscopy technologies have the great potential to aid in the identification of better intervention strategies for this devastating disease. In this review, we emphasize the current knowledge and the potential significance of imaging technologies in understanding the infection process of visceralizing Leishmania species. Then, we discuss how application of innovative microscopy technologies to the study of VL will provide rich opportunities for investigating host-parasite interactions at a previously unexplored level and elucidating visceral disease-promoting mechanisms. © 2013 John Wiley & Sons Ltd.

Technology-enhanced human interaction in psychotherapy.

PubMed

Imel, Zac E; Caperton, Derek D; Tanana, Michael; Atkins, David C

2017-07-01

Psychotherapy is on the verge of a technology-inspired revolution. The concurrent maturation of communication, signal processing, and machine learning technologies begs an earnest look at how these technologies may be used to improve the quality of psychotherapy. Here, we discuss 3 research domains where technology is likely to have a significant impact: (1) mechanism and process, (2) training and feedback, and (3) technology-mediated treatment modalities. For each domain, we describe current and forthcoming examples of how new technologies may change established applications. Moreover, for each domain we present research questions that touch on theoretical, systemic, and implementation issues. Ultimately, psychotherapy is a decidedly human endeavor, and thus the application of modern technology to therapy must capitalize on-and enhance-our human capacities as counselors, students, and supervisors. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Identification and Characterization of ART-27, a Novel Coactivator for the Androgen Receptor N Terminus

PubMed Central

Markus, Steven M.; Taneja, Samir S.; Logan, Susan K.; Li, Wenhui; Ha, Susan; Hittelman, Adam B.; Rogatsky, Inez; Garabedian, Michael J.

2002-01-01

The androgen receptor (AR) is a ligand-regulated transcription factor that stimulates cell growth and differentiation in androgen-responsive tissues. The AR N terminus contains two activation functions (AF-1a and AF-1b) that are necessary for maximal transcriptional enhancement by the receptor; however, the mechanisms and components regulating AR transcriptional activation are not fully understood. We sought to identify novel factors that interact with the AR N terminus from an androgen-stimulated human prostate cancer cell library using a yeast two-hybrid approach designed to identify proteins that interact with transcriptional activation domains. A 157-amino acid protein termed ART-27 was cloned and shown to interact predominantly with the AR153–336, containing AF-1a and a part of AF-1b, localize to the nucleus and increase the transcriptional activity of AR when overexpressed in cultured mammalian cells. ART-27 also enhanced the transcriptional activation by AR153–336 fused to the LexA DNA-binding domain but not other AR N-terminal subdomains, suggesting that ART-27 exerts its effect via an interaction with a defined region of the AR N terminus. ART-27 interacts with AR in nuclear extracts from LNCaP cells in a ligand-independent manner. Interestingly, velocity gradient sedimentation of HeLa nuclear extracts suggests that native ART-27 is part of a multiprotein complex. ART-27 is expressed in a variety of human tissues, including sites of androgen action such as prostate and skeletal muscle, and is conserved throughout evolution. Thus, ART-27 is a novel cofactor that interacts with the AR N terminus and plays a role in facilitating receptor-induced transcriptional activation. PMID:11854421

Identification and characterization of ART-27, a novel coactivator for the androgen receptor N terminus.

PubMed

Markus, Steven M; Taneja, Samir S; Logan, Susan K; Li, Wenhui; Ha, Susan; Hittelman, Adam B; Rogatsky, Inez; Garabedian, Michael J

2002-02-01

The androgen receptor (AR) is a ligand-regulated transcription factor that stimulates cell growth and differentiation in androgen-responsive tissues. The AR N terminus contains two activation functions (AF-1a and AF-1b) that are necessary for maximal transcriptional enhancement by the receptor; however, the mechanisms and components regulating AR transcriptional activation are not fully understood. We sought to identify novel factors that interact with the AR N terminus from an androgen-stimulated human prostate cancer cell library using a yeast two-hybrid approach designed to identify proteins that interact with transcriptional activation domains. A 157-amino acid protein termed ART-27 was cloned and shown to interact predominantly with the AR(153-336), containing AF-1a and a part of AF-1b, localize to the nucleus and increase the transcriptional activity of AR when overexpressed in cultured mammalian cells. ART-27 also enhanced the transcriptional activation by AR(153-336) fused to the LexA DNA-binding domain but not other AR N-terminal subdomains, suggesting that ART-27 exerts its effect via an interaction with a defined region of the AR N terminus. ART-27 interacts with AR in nuclear extracts from LNCaP cells in a ligand-independent manner. Interestingly, velocity gradient sedimentation of HeLa nuclear extracts suggests that native ART-27 is part of a multiprotein complex. ART-27 is expressed in a variety of human tissues, including sites of androgen action such as prostate and skeletal muscle, and is conserved throughout evolution. Thus, ART-27 is a novel cofactor that interacts with the AR N terminus and plays a role in facilitating receptor-induced transcriptional activation.

Longitudinal Assessment of Systemic and Genital Tract Inflammatory Markers and Endogenous Genital Tract E. coli Inhibitory Activity in HIV-Infected and Uninfected Women.

PubMed

Keller, Marla J; McGinn, Aileen P; Lo, Yungtai; Huber, Ashley; Espinoza, Lilia; Minkoff, Howard; Colie, Christine; Nowicki, Marek J; D'Souza, Gypsyamber; Anastos, Kathryn

2016-06-01

Stability over time of systemic and mucosal immunity and their associations with bacterial vaginosis (BV) and HIV-specific parameters were assessed. Immune mediators and HIV viral load in plasma and cervicovaginal lavage (CVL), E. coli inhibition, and Nugent score were measured at three semiannual visits among 94 participants in the Women's Interagency HIV Study. Mixed models identified the factors associated with immune mediators. There was higher E. coli inhibition and lower inflammation over time in the genital tract and systemically. BV was consistently associated with higher CVL inflammatory mediators and lower CVL E. coli inhibition. HIV-infected women with higher CD4 counts had lower systemic and genital inflammatory mediators, and genital HIV shedding was associated with higher CVL inflammatory mediators. Use of antiretroviral therapy (ART) was associated with lower plasma and CVL mediators, but higher E. coli inhibition. HIV and BV are linked to inflammation, and ART may be associated with improved vaginal health. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Collaborative routes to clarifying the murky waters of aqueous supramolecular chemistry.

PubMed

Cremer, Paul S; Flood, Amar H; Gibb, Bruce C; Mobley, David L

2017-12-19

On planet Earth, water is everywhere: the majority of the surface is covered with it; it is a key component of all life; its vapour and droplets fill the lower atmosphere; and even rocks contain it and undergo geomorphological changes because of it. A community of physical scientists largely drives studies of the chemistry of water and aqueous solutions, with expertise in biochemistry, spectroscopy and computer modelling. More recently, however, supramolecular chemists - with their expertise in macrocyclic synthesis and measuring supramolecular interactions - have renewed their interest in water-mediated non-covalent interactions. These two groups offer complementary expertise that, if harnessed, offer to accelerate our understanding of aqueous supramolecular chemistry and water writ large. This Review summarizes the state-of-the-art of the two fields, and highlights where there is latent chemical space for collaborative exploration by the two groups.

Collaborative routes to clarifying the murky waters of aqueous supramolecular chemistry

NASA Astrophysics Data System (ADS)

Cremer, Paul S.; Flood, Amar H.; Gibb, Bruce C.; Mobley, David L.

2018-01-01

On planet Earth, water is everywhere: the majority of the surface is covered with it; it is a key component of all life; its vapour and droplets fill the lower atmosphere; and even rocks contain it and undergo geomorphological changes because of it. A community of physical scientists largely drives studies of the chemistry of water and aqueous solutions, with expertise in biochemistry, spectroscopy and computer modelling. More recently, however, supramolecular chemists -- with their expertise in macrocyclic synthesis and measuring supramolecular interactions -- have renewed their interest in water-mediated non-covalent interactions. These two groups offer complementary expertise that, if harnessed, offer to accelerate our understanding of aqueous supramolecular chemistry and water writ large. This Review summarizes the state-of-the-art of the two fields, and highlights where there is latent chemical space for collaborative exploration by the two groups.

Teachers' Dispositions towards the Role of Digital Devices in Play-Based Pedagogy in Early Childhood Education

ERIC Educational Resources Information Center

Palaiologou, Ioanna

2016-01-01

A body of research is emerging on early childhood education teachers' views on the integration of digital technologies in their practice. Despite evidence of the digitalisation of homes in affluent societies and children's interactions in highly mediated digital environments, few teachers so far have integrated digital devices into a play-based…

Community-Based Outdoor Education Using a Local Approach to Conservation

ERIC Educational Resources Information Center

Maeda, Kazushi

2005-01-01

Local people of a community interact with nature in a way that is mediated by their local cultures and shape their own environment. We need a local approach to conservation for the local environment adding to the political or technological approaches for global environmental problems such as the destruction of the ozone layer or global warming.…

A Multivocal Approach in the Analysis of Online Dialogue in the Language-Focused Classroom in Higher Education

ERIC Educational Resources Information Center

Dahlberg, Giulia Messina

2017-01-01

The study presented here is interested in understanding the ways in which social interaction in technology-mediated institutional settings is constrained and afforded by what Pennycook defines as "critical moments" in the educational experience. Drawing on Social Learning Analytics and on the concepts of heteroglossia, contingency and…

Computer Utilization in Industrial Arts/Technology Education. Curriculum Guide.

ERIC Educational Resources Information Center

Connecticut Industrial Arts Association.

This guide is intended to assist industrial arts/technology education teachers in helping students in grades K-12 understand the impact of computers and computer technology in the world. Discussed in the introductory sections are the ways in which computers have changed the face of business, industry, and education and training; the scope and…

Applications of Videodisc Technology to Language Arts, Grades K-12: A Review of the Literature.

ERIC Educational Resources Information Center

Lewis, Martina E.

This monograph traces the history of videodisc technology, describes the videodisc and its functions, reviews classroom applications and limitations, and discusses the future use of videodisc technology in elementary and secondary language arts classes. Two videodisc formats are discussed--constant linear velocity (CLV), and constant angular…

Present Place and the Future of Computing and Technology on the College Campus.

ERIC Educational Resources Information Center

Powell, James L.

Serious budgetary and administrative questions concerning educational computing and technology confront liberal arts college administrators. What will be the impact of microcomputers and other technologies on a liberal arts education? Since monies are less and less apt to come from outside grants, especially for non-innovative institutions, and…

A Comparison of Self-Reported Educational Technology Integration Proficiencies and Evidence-Based Educational Technology Integration Practices among Select Elementary Language Arts Teachers

ERIC Educational Resources Information Center

Anderson, Monika R.

2014-01-01

The purpose of this study was to use a variety of techniques and data sources, to describe and to compare the self-reported educational technology integration proficiency levels with the evidence-based educational technology integration practices among select elementary language arts teachers. A collective case study design (Stake, 1995) was used…

Remote photonic metrology in the conservation of cultural heritage

NASA Astrophysics Data System (ADS)

Tornari, Vivi; Pedrini, G.; Osten, W.

2013-05-01

Photonic technologies play a leading innovative role of research in the fields of Cultural Heritage (CH) conservation, preservation and digitisation. In particular photonic technologies have introduced a new indispensable era of research in the conservation of cultural artefacts expanding from decorative objects, paintings, sculptures, monuments to archaeological sites and including fields of application as diverse as materials characterisation to restoration practices and from defect topography to 3d artwork reconstruction. Thus the last two decades photonic technologies have emerged as unique answer or most competitive alternative into many long-term standing disputes in conservation and restoration of Cultural Heritage. Despite the impressive advances on the state-of-the-art ranging from custom-made system development to new methods and practises, photonic research and technological developments remain incoherently scattered and fragmented with a significant amount of duplication of work and misuse of resources. In this context, further progress should aim to capitalise on the so far achieved milestones in any of the diverse applications flourished in the field of CH. Embedding of experimental facilities and conclusions seems the only way to secure the progress beyond the existing state of the art and its false use. The solution to this embedment seems possible through the new computing environments. Cloud computing environment and remote laboratory access hold the missing research objective to bring the leading research together and integrate the achievements. The cloud environment would allow experts from museums, galleries, historical sites, art historians, conservators, scientists and technologists, conservation and technical laboratories and SMEs to interact their research, communicate their achievements and share data and resources. The main instrument of this integration is the creation of a common research platform termed here Virtual Laboratory allowing not only remote research, inspection and evaluation, but also providing the results to the members and the public with instant and simultaneous access to necessary information, knowledge and technologies. In this paper it is presented the concept and first results confirming the potential of implementing metrology techniques as remote digital laboratory facilities in artwork structural assessment. The method paves the way of the general objective to introduce remote photonic technologies in the sensitive field of Cultural Heritage.

[The virtual environment of a research group: the tutors' perspective].

PubMed

Prado, Cláudia; Casteli, Christiane Pereira Martins; Lopes, Tania Oliveira; Kobayashi, Rika M; Peres, Heloísa Helena Ciqueto; Leite, Maria Madalena Januário

2012-02-01

The Grupo de Estudos e Pesquisas de Tecnologia da Informação nos Processos de Trabalho em Enfermagem (Study and Research Group for Information Technology in the Nursing Working Processes, GEPETE) has the purpose of producing and socializing knowledge in information technology and health and nursing communication, making associations with research groups in this field and promoting student participation. This study was performed by the group tutors with the objective to report on the development of the virtual learning environment (VLE) and the tutors' experience as mediators of a research group using the Moodle platform. To do this, a VLE was developed and pedagogical mediation was performed following the theme of mentoring. An initial diagnosis was made of the difficulties in using this technology in interaction and communication, which permitted the proposal of continuing to use the platform as a resource to support research activities, offer lead researchers the mechanisms to socialize projects and offer the possibility of giving advice at a distance.

Outcome measures to evaluate new technology for tonsillectomy: preliminary experience with Coblation

NASA Astrophysics Data System (ADS)

Shah, Udayan K.; Puchalski, Robert; Briggs, Marianne; Chiavacci, Rosetta; Galinkin, Jeffrey

2001-05-01

Evaluating the benefits of new surgical technologies does not end with the observation of successful instrument-to- tissue interaction. The impact of new technologies in medicine today is also gauged by improvements in patients' daily activities and performance. We present our outcomes assessment tool for judging the value of applying a novel tonsillectomy technique, plasma- mediated ablation using Coblation technology. Plasma- mediated ablation (PMA) achieves soft tissue resection in the oropharynx by energizing protons to break bonds. Less heat is released, allowing for less thermal injury, and possibly less pain, than with tonsillectomy performed using electrocautery alone. Children undergoing tonsillectomy by PMA, were evaluated using our outcomes-based scale, which asked families to report the degree of interruption of normal activities for the patient and their family during the post-tonsillectomy recovery period. A preliminary review of several outcomes assessments exemplify the benefits and limitations of this tool. The tracking of valuable data is weighed against the limitations of a short time course relative to the duration of disability, and a poor response rate. Future work aims to improve this data collection tool to allow application to other new technologies in otolaryngology.

The bar{P}ANDA Experiment at FAIR — Subatomic Physics with Antiprotons

NASA Astrophysics Data System (ADS)

Messchendorp, Johan

The non-perturbative nature of the strong interaction leads to spectacular phenomena, such as the formation of hadronic matter, color confinement, and the generation of the mass of visible matter. To get deeper insight into the underlying mechanisms remains one of the most challenging tasks within the field of subatomic physics. The antiProton ANnihilations at DArmstadt (bar{P}ANDA) collaboration has the ambition to address key questions in this field by exploiting a cooled beam of antiprotons at the High Energy Storage Ring (HESR) at the future Facility for Antiproton and Ion Research (FAIR) combined with a state-of-the-art and versatile detector. This contribution will address some of the unique features of bar{P}ANDA that give rise to a promising physics program together with state-of-the-art technological developments.

Can assisted reproductive technologies cause adult-onset disease? Evidence from human and mouse

PubMed Central

Vrooman, Lisa A.; Bartolomei, Marisa S.

2016-01-01

Millions of children have been born worldwide though assisted reproductive technologies (ART). Consistent with the Developmental Origins of Health and Disease hypothesis, there is concern that ART can induce adverse effects, especially because procedures coincide with epigenetic reprogramming events. Although the majority of studies investigating the effects of ART have focused on perinatal outcomes, more recent studies demonstrate that ART-conceived children may be at increased risk for postnatal effects. Here, we present the current epidemiological evidence that ART-conceived children have detectable differences in blood pressure, body composition, and glucose homeostasis. Similar effects are observed in the ART mouse model, which have no underlying infertility, suggesting that cardiometabolic effects are likely caused by ART procedures and not due to reasons related to infertility. We propose that the mouse system can, consequently, be used to adequately study, modify, and improve outcomes for ART children. PMID:27474254

The Tools, Approaches and Applications of Visual Literacy in the Visual Arts Department of Cross River University of Technology, Calabar, Nigeria

ERIC Educational Resources Information Center

Ecoma, Victor

2016-01-01

The paper reflects upon the tools, approaches and applications of visual literacy in the Visual Arts Department of Cross River University of Technology, Calabar, Nigeria. The objective of the discourse is to examine how the visual arts training and practice equip students with skills in visual literacy through methods of production, materials and…

Fuzzing: The State of the Art

DTIC Science & Technology

2012-02-01

UNCLASSIFIED Fuzzing: The State of the Art Richard McNally, Ken Yiu, Duncan Grove and Damien Gerhardy Command, Control, Communications and...Intelligence Division Defence Science and Technology Organisation DSTO–TN–1043 ABSTRACT Fuzzing is an approach to software testing where the system being tested...features of fuzzers and recent advances in their development, in order to discern the current state of the art in fuzzing technologies, and to extrapolate

Mobile Learning and Art Museums: A Case Study of a New Art Interpretation Approach for Visitor Engagement through Mobile Media

ERIC Educational Resources Information Center

Benito, Victoria López

2014-01-01

Nowadays Mobile technologies in Museums and especially in Art Museums are a popular way of communication with their audiences. These kinds of technologies have a high communicative potential and also could be a tool for marketing, information, engagement and learning as well. However with regards how these resources explain the meaning of works of…

Selecting and Acquiring Art Materials in the Academic Library: Meeting the Needs of the Studio Artist

ERIC Educational Resources Information Center

Lorenzen, Elizabeth A.

2004-01-01

As technology is shaping today's art world, parallel changes are happening in the ways art book collections are identified and acquired. The purpose of this article is to identify the changes transpiring in the worlds of the artist and library acquisitions, and to evaluate the ways in which the changes effected by technological applications in the…

Creating Meaningful Art Experiences with Assistive Technology for Students with Physical, Visual, Severe, and Multiple Disabilities

ERIC Educational Resources Information Center

Coleman, Mari Beth; Cramer, Elizabeth Stephanie

2015-01-01

Various levels of assistive technology can be used in the art classroom to provide a fulfilling artmaking experience for all levels of learners. The purpose of this article is to add to the body of knowledge by providing ideas generated from collaboration between the fields of special education and art education that the authors feel will benefit…

Creativity and Technology in Mathematics: From Story Telling to Algorithmic with Op'Art

ERIC Educational Resources Information Center

Mercat, Christian; Filho, Pedro Lealdino; El-Demerdash, Mohamed

2017-01-01

This article describes some of the results of the European project mcSquared (http://mc2-project.eu/) regarding the use of Op'Art and optical illusion pieces as a tool to foster modeling and creative mathematical thinking in students. We present briefly the c-book technology and some results we got experimenting it. The Op'Art movement, with…

Applying Multi-Touch Technology to Facilitate the Learning of Art Appreciation: From the View of Motivation and Annotation

ERIC Educational Resources Information Center

Hung, Hui-Chun; Young, Shelley Shwu-Ching

2017-01-01

Handheld technologies with multi-touch functions have been embraced by the young generation and become their important tool for social and learning purposes. The purpose of this study was to explore how the state-of-art devices could be integrated into authentic art appreciation courses to motivate and enhance students' learning. It was conducted…

An international view of surgically assisted conception and surrogacy tourism.

PubMed

Ahmad, Nehaluddin

2011-01-01

Modern medicine, specifically assisted reproductive technology (ART), has overtaken the law in many jurisdictions around the world. New technologies and practices open a Pandora's Box of ethical, religious, social and legal questions, and may present a variety of significant legal problems to the courts and legislators. Surrogate motherhood and pregnancy through ART have both attracted controversy. Some groups condemn ART and want it banned while its supporters acknowledge there is a need for legislative guidelines and regulations. A proposed statute, the Assisted Reproductive Technique Services Act, aimed at regulating reproductive technologies, including surrogacy arrangements, will be introduced in the Malaysian parliament, probably in 2012, and the Assisted Reproductive Technology (Regulation) Bill 2010 is already before the Indian parliament. This paper will discuss several of the potential socio-legal issues surrounding ART in the light of the complex situation, with a comparative analysis of the Malaysian, USA, UK and Indian positions.

The role of prefrontal and parietal cortices in esthetic appreciation of representational and abstract art: a TMS study.

PubMed

Cattaneo, Zaira; Lega, Carlotta; Gardelli, Chiara; Merabet, Lotfi B; Cela-Conde, Camilo J; Nadal, Marcos

2014-10-01

To explain the biological foundations of art appreciation is to explain one of our species' distinctive traits. Previous neuroimaging and electrophysiological studies have pointed to the prefrontal and the parietal cortex as two critical regions mediating esthetic appreciation of visual art. In this study, we applied transcranial magnetic stimulation (TMS) over the left prefrontal cortex and the right posterior parietal cortex while participants were evaluating whether they liked, and by how much, a particular painting. By depolarizing cell membranes in the targeted regions, TMS transiently interferes with the activity of specific cortical areas, which allows clarifying their role in a given task. Our results show that both regions play a fundamental role in mediating esthetic appreciation. Critically though, the effects of TMS varied depending on the type of art considered (i.e. representational vs. abstract) and on participants' a-priori inclination toward one or the other. Copyright © 2014 Elsevier Inc. All rights reserved.

Micro- and nanodevices integrated with biomolecular probes.

PubMed

Alapan, Yunus; Icoz, Kutay; Gurkan, Umut A

2015-12-01

Understanding how biomolecules, proteins and cells interact with their surroundings and other biological entities has become the fundamental design criterion for most biomedical micro- and nanodevices. Advances in biology, medicine, and nanofabrication technologies complement each other and allow us to engineer new tools based on biomolecules utilized as probes. Engineered micro/nanosystems and biomolecules in nature have remarkably robust compatibility in terms of function, size, and physical properties. This article presents the state of the art in micro- and nanoscale devices designed and fabricated with biomolecular probes as their vital constituents. General design and fabrication concepts are presented and three major platform technologies are highlighted: microcantilevers, micro/nanopillars, and microfluidics. Overview of each technology, typical fabrication details, and application areas are presented by emphasizing significant achievements, current challenges, and future opportunities. Copyright © 2015 Elsevier Inc. All rights reserved.

Creating Nanotechnicians for the 21st Century Workplace

NASA Astrophysics Data System (ADS)

Burke, Michael; Jean, Kristi; Brown, Cheryl; Barrett, Rick; Leopold, Carrie

The North Dakota State College of Science (NDSCS) Nanoscience Technology Training Program was designed and implemented to meet the growing demand for technicians skilled in nanofabrication, surface analysis and production of various micro and nano-scale products. The program emphasizes hands-on training and utilizes a state-of-the-art Applied Science and Advanced Manufacturing Training Laboratory to develop the KSA’s (knowledge, skills, attitudes) needed by industry. Two-year Associate in Applied Science degree, diploma and certificate tracks are offered in four industry focus areas; nanotechnology, microelectronics technology, bio-fuels technology and biotechnology. Students learn to work in multidisciplinary teams on design, prototyping, analysis and manufacturing processes of products. The program also hosts an extensive hands-on outreach program which interacted with over 8000 secondary school science students and 500 teachers in the first 12 months of operation.

Distributed 3D Information Visualization - Towards Integration of the Dynamic 3D Graphics and Web Services

NASA Astrophysics Data System (ADS)

Vucinic, Dean; Deen, Danny; Oanta, Emil; Batarilo, Zvonimir; Lacor, Chris

This paper focuses on visualization and manipulation of graphical content in distributed network environments. The developed graphical middleware and 3D desktop prototypes were specialized for situational awareness. This research was done in the LArge Scale COllaborative decision support Technology (LASCOT) project, which explored and combined software technologies to support human-centred decision support system for crisis management (earthquake, tsunami, flooding, airplane or oil-tanker incidents, chemical, radio-active or other pollutants spreading, etc.). The performed state-of-the-art review did not identify any publicly available large scale distributed application of this kind. Existing proprietary solutions rely on the conventional technologies and 2D representations. Our challenge was to apply the "latest" available technologies, such Java3D, X3D and SOAP, compatible with average computer graphics hardware. The selected technologies are integrated and we demonstrate: the flow of data, which originates from heterogeneous data sources; interoperability across different operating systems and 3D visual representations to enhance the end-users interactions.

A unification of mediation and interaction: a four-way decomposition

PubMed Central

VanderWeele, Tyler J.

2014-01-01

It is shown that the overall effect of an exposure on an outcome, in the presence of a mediator with which the exposure may interact, can be decomposed into four components: (i) the effect of the exposure in the absence of the mediator, (ii) the interactive effect when the mediator is left to what it would be in the absence of exposure, (iii) a mediated interaction, and (iv) a pure mediated effect. These four components, respectively, correspond to the portion of the effect that is due to neither mediation nor interaction, to just interaction (but not mediation), to both mediation and interaction, and to just mediation (but not interaction). This four-way decomposition unites methods that attribute effects to interactions and methods that assess mediation. Certain combinations of these four components correspond to measures for mediation, while other combinations correspond to measures of interaction previously proposed in the literature. Prior decompositions in the literature are in essence special cases of this four-way decomposition. The four-way decomposition can be carried out using standard statistical models, and software is provided to estimate each of the four components. The four-way decomposition provides maximum insight into how much of an effect is mediated, how much is due to interaction, how much is due to both mediation and interaction together, and how much is due to neither. PMID:25000145

To boldly go where no relationship has gone before: Commentary on interpersonal relationships in the digital age.

PubMed

Okdie, Bradley M; Ewoldsen, David R

2018-01-01

Individuals have a need to maintain positive social interactions, and with the advent of new-media technologies, there are a myriad ways individuals can satisfy this need by engaging socially in mediated (non-face-to-face) communication, hence the need for a special issue on "Relationships in the Digital Age." The articles in this special issue reflect the need to answer theoretical questions brought forth by the increased tendency for individuals to create and maintain interpersonal relationships through mediated forms of communication. The commentary highlights the need for increased research on mediated interpersonal relationships by psychologists and discusses how the articles in the issue can be used to answer theoretical questions about mediated interpersonal communication. The article ends with speculation on how media may create social spaces that may be advantageous for some individuals.

To boldly go where no relationship has gone before: commentary on interpersonal relationships in the digital age.

PubMed

Okdie, Bradley M; Ewoldsen, David R

2018-04-19

Individuals have a need to maintain positive social interactions and with the advent of new media technologies, there are a myriad ways individuals can satisfy this need by engaging socially in mediated (non-face-to-face) communication, hence the need for a special issue on Relationships in the Digital Age. The articles in this special issue reflect the need to answer theoretical questions brought forth by the increased tendency for individuals to create and maintain interpersonal relationships through mediated forms of communication. The commentary highlights the need for increased research on mediated interpersonal relationships by psychologists and discusses how the articles in the issue can be used to answer theoretical questions about mediated interpersonal communication. The article ends with speculation on how media may create social spaces that may be advantageous for some individuals.

Automated identification of protein-ligand interaction features using Inductive Logic Programming: a hexose binding case study.

PubMed

A Santos, Jose C; Nassif, Houssam; Page, David; Muggleton, Stephen H; E Sternberg, Michael J

2012-07-11

There is a need for automated methods to learn general features of the interactions of a ligand class with its diverse set of protein receptors. An appropriate machine learning approach is Inductive Logic Programming (ILP), which automatically generates comprehensible rules in addition to prediction. The development of ILP systems which can learn rules of the complexity required for studies on protein structure remains a challenge. In this work we use a new ILP system, ProGolem, and demonstrate its performance on learning features of hexose-protein interactions. The rules induced by ProGolem detect interactions mediated by aromatics and by planar-polar residues, in addition to less common features such as the aromatic sandwich. The rules also reveal a previously unreported dependency for residues cys and leu. They also specify interactions involving aromatic and hydrogen bonding residues. This paper shows that Inductive Logic Programming implemented in ProGolem can derive rules giving structural features of protein/ligand interactions. Several of these rules are consistent with descriptions in the literature. In addition to confirming literature results, ProGolem's model has a 10-fold cross-validated predictive accuracy that is superior, at the 95% confidence level, to another ILP system previously used to study protein/hexose interactions and is comparable with state-of-the-art statistical learners.

Emerging materials for lowering atmospheric carbon

DOE PAGES

Barkakaty, Balaka; Sumpter, Bobby G.; Ivanov, Ilia N.; ...

2016-12-08

CO 2 emissions from anthropogenic sources and the rate at which they increase could have deep global ramifications such as irreversible climate change and increased natural disasters. Because greater than 50% of anthropogenic CO 2 emissions come from small, distributed sectors such as homes, offices, and transportation sources, most renewable energy systems and on-site carbon capture technologies for reducing future CO 2 emissions cannot be effectively utilized. This problem might be mediated by considering novel materials and technologies for directly capturing/removing CO 2 from air. But, compared to materials for capturing CO 2 at on-site emission sources, materials for capturingmore » CO 2 directly from air must be more selective to CO 2, and should operate and be stable at near ambient conditions. Here, we briefly summarize the recent developments in materials for capturing carbon dioxide directly from air. Furthermore, we discuss the challenges in this field and offer a perspective for developing the current state-of-art and also highlight the potential of a few recent discoveries in materials science that show potential for advanced application of air capture technology.« less

Stress and Displacement Analysis of Microreactors during Thermal and Vacuum Loading

DTIC Science & Technology

2017-09-07

and extend the available energy density well beyond state-of-the-art battery technology (140 W·h/kg for rechargeable lithium [Li]- ion technology).1...time. In the 10–100 W+ power range, battery technology is the best solution currently available, but higher-energy dense technologies are needed to...augment batteries and extend the available energy density well beyond state-of-the-art battery technology. One way to approach this is to take

Perception of approaching and retreating floor-projected shapes in a large, immersive, multimedia learning environment.

PubMed

Dolgov, Igor; Birchfield, David A; McBeath, Michael K; Thornburg, Harvey; Todd, Christopher G

2009-04-01

Perception of floor-projected moving geometric shapes was examined in the context of the Situated Multimedia Arts Learning Laboratory (SMALLab), an immersive, mixed-reality learning environment. As predicted, the projected destinations of shapes which retreated in depth (proximal origin) were judged significantly less accurately than those that approached (distal origin). Participants maintained similar magnitudes of error throughout the session, and no effect of practice was observed. Shape perception in an immersive multimedia environment is comparable to the real world. One may conclude that systematic exploration of basic psychological phenomena in novel mediated environments is integral to an understanding of human behavior in novel human-computer interaction architectures.

Cucurbit[n]uril-Based Microcapsules Self-Assembled within Microfluidic Droplets: A Versatile Approach for Supramolecular Architectures and Materials

PubMed Central

2017-01-01

Conspectus Microencapsulation is a fundamental concept behind a wide range of daily applications ranging from paints, adhesives, and pesticides to targeted drug delivery, transport of vaccines, and self-healing concretes. The beauty of microfluidics to generate microcapsules arises from the capability of fabricating monodisperse and micrometer-scale droplets, which can lead to microcapsules/particles with fine-tuned control over size, shape, and hierarchical structure, as well as high reproducibility, efficient material usage, and high-throughput manipulation. The introduction of supramolecular chemistry, such as host–guest interactions, endows the resultant microcapsules with stimuli-responsiveness and self-adjusting capabilities, and facilitates hierarchical microstructures with tunable stability and porosity, leading to the maturity of current microencapsulation industry. Supramolecular architectures and materials have attracted immense attention over the past decade, as they open the possibility to obtain a large variety of aesthetically pleasing structures, with myriad applications in biomedicine, energy, sensing, catalysis, and biomimicry, on account of the inherent reversible and adaptive nature of supramolecular interactions. As a subset of supramolecular interactions, host–guest molecular recognition involves the formation of inclusion complexes between two or more moieties, with specific three-dimensional structures and spatial arrangements, in a highly controllable and cooperative manner. Such highly selective, strong yet dynamic interactions could be exploited as an alternative methodology for programmable and controllable engineering of supramolecular architectures and materials, exploiting reversible interactions between complementary components. Through the engineering of molecular structures, assemblies can be readily functionalized based on host–guest interactions, with desirable physicochemical characteristics. In this Account, we summarize the current state of development in the field of monodisperse supramolecular microcapsules, fabricated through the integration of traditional microfluidic techniques and interfacial host–guest chemistry, specifically cucurbit[n]uril (CB[n])-mediated host–guest interactions. Three different strategies, colloidal particle-driven assembly, interfacial condensation-driven assembly and electrostatic interaction-driven assembly, are classified and discussed in detail, presenting the methodology involved in each microcapsule formation process. We highlight the state-of-the-art in design and control over structural complexity with desirable functionality, as well as promising applications, such as cargo delivery stemming from the assembled microcapsules. On account of its dynamic nature, the CB[n]-mediated host–guest complexation has demonstrated efficient response toward various external stimuli such as UV light, pH change, redox chemistry, and competitive guests. Herein, we also demonstrate different microcapsule modalities, which are engineered with CB[n] host–guest chemistry and also can be disrupted with the aid of external stimuli, for triggered release of payloads. In addition to the overview of recent achievements and current limitations of these microcapsules, we finally summarize several perspectives on tunable cargo loading and triggered release, directions, and challenges for this technology, as well as possible strategies for further improvement, which will lead to substainitial progress of host–guest chemistry in supramolecular architectures and materials. PMID:28075551

Integrating Art.

ERIC Educational Resources Information Center

BCATA Journal for Art Teachers, 1991

1991-01-01

These articles focus on art as a component of interdisciplinary integration. (1) "Integrated Curriculum and the Visual Arts" (Anna Kindler) considers various aspects of integration and implications for art education. (2) "Integration: The New Literacy" (Tim Varro) illustrates how the use of technology can facilitate…

An Introduction to the Computerized Assessment of Art-Based Instruments

ERIC Educational Resources Information Center

Mattson, Donald C.

2012-01-01

This article provides a historical overview of computer-assisted art assessment, introduces the basic concepts of computerized assessment of art-based instruments (CAABI), and offers a tutorial to assist art therapists in the study of its application. Understanding this emergent technology may assist art therapists in overcoming hesitancy in…

'Emotional rights', moral reasoning, and Jewish-Arab alliances in the regulation of in-vitro-fertilization in israel: theorizing the unexpected consequences of assisted reproductive technologies.

PubMed

Gooldin, Sigal

2013-04-01

Consumption rates of assisted reproductive technologies (ARTs) in Israel is internationally unprecedented, a phenomenon that has been the subject of growing anthropological and sociological attention. Explanations for the singular extent of ARTs use in Israel tend to pre-assume and conceptually prioritize the symbolic and political power of pro-natalist discourses, Jewish religious values, and the demographic interests of the Jewish state. This article attempts to understand the exceptional usage of IVF in Israel in terms of its emergent meanings and unexpected effects in a particular local setup. The question that this article tries to answer is: How is the 'Israeli character' of IVF emerges within and through the interactive practice of moral justifications, and how might this medical technology affect the networks within which it is enmeshed? The article is based on a case-study analysis of a public dispute that took place in 2003-2004 over the extent of public funding for fertility treatments. Ethnographic analysis of parliament discussions, media coverage, and an online forum of IVF consumers recorded three frames of justification for the uniquely generous public funding scheme of IVF in Israel: 'rational-economic', 'nationalist', and 'liberal'. The latter assumes shared 'emotional vulnerability' of all 'childless' Israelis, Jews and Arabs alike and advocates a universal language of 'emotional rights' and 'human rights'. This liberal framing of IVF, which is the most persuasive justification in the dispute, blurs dichotomous rivalries between Jews and Arabs and generates a potential for alliances between traditionally rival sectors. These are some of the unexpected and non-intuitive consequences of ARTs in Israel. Copyright © 2013 Elsevier Ltd. All rights reserved.

Adaptive and perceptual learning technologies in medical education and training.

PubMed

Kellman, Philip J

2013-10-01

Recent advances in the learning sciences offer remarkable potential to improve medical education and maximize the benefits of emerging medical technologies. This article describes 2 major innovation areas in the learning sciences that apply to simulation and other aspects of medical learning: Perceptual learning (PL) and adaptive learning technologies. PL technology offers, for the first time, systematic, computer-based methods for teaching pattern recognition, structural intuition, transfer, and fluency. Synergistic with PL are new adaptive learning technologies that optimize learning for each individual, embed objective assessment, and implement mastery criteria. The author describes the Adaptive Response-Time-based Sequencing (ARTS) system, which uses each learner's accuracy and speed in interactive learning to guide spacing, sequencing, and mastery. In recent efforts, these new technologies have been applied in medical learning contexts, including adaptive learning modules for initial medical diagnosis and perceptual/adaptive learning modules (PALMs) in dermatology, histology, and radiology. Results of all these efforts indicate the remarkable potential of perceptual and adaptive learning technologies, individually and in combination, to improve learning in a variety of medical domains. Reprint & Copyright © 2013 Association of Military Surgeons of the U.S.

Extracellular Electron Uptake: Among Autotrophs and Mediated by Surfaces.

PubMed

Tremblay, Pier-Luc; Angenent, Largus T; Zhang, Tian

2017-04-01

Autotrophic microbes can acquire electrons from solid donors such as steel, other microbial cells, or electrodes. Based on this feature, bioprocesses are being developed for the microbial electrosynthesis (MES) of useful products from the greenhouse gas CO 2 . Extracellular electron-transfer mechanisms involved in the acquisition of electrons from metals by electrical microbially influenced corrosion (EMIC), from other living cells by interspecies electron transfer (IET), or from an electrode during MES rely on: (i) mediators such as H 2 ; (ii) physical contact through electron-transfer proteins; or (iii) mediator-generating enzymes detached from cells. This review explores the interactions of autotrophs with solid electron donors and their importance in nature and for biosustainable technologies. Copyright © 2016 Elsevier Ltd. All rights reserved.

Art in the Service of Science

NASA Astrophysics Data System (ADS)

Asmus, J. F.

In fields such as studio art, art conservation, archaeology, anthropology, music, and architecture it is often understood that many of the advances emerge from the introduction of new developments from science and technology. Scientific research is often justified on the basis of its past as well as potential future fallout into other endeavors as diverse as medicine, manufacturing, and the humanities. The diffusion of scientific innovation into the practice of art conservation has been punctuated by the introduction of a series of diverse technologies. Trace element and isotopic analyses, infrared imaging, ultraviolet fluorescence inspection, advanced coatings and adhesives, scanning electron microscopy, and photon/electron microprobes are notable examples. For the past thirty years various laser technologies have demonstrated utility in the practice of art conservation, as well. These include photon cleaning and divestment, holographic display and nondestructive analysis, surface characterization through laser fluorescence, radiation scattering and absorption, as well as laser-induced ultrasound. At the dawn of laser technology's introduction into the art conservation field (1972-74) the Center for Art/Science Studies (CASS) was established at the University of California, San Diego (UCSD) with the hope of accelerating and broadening the diffusion of scientific developments into art conservation practice. Surprisingly, one of the first events in the CASS/UCSD transpired when a Visual Arts Department student employed a primitive laser statue cleaner to "correct" a silk-screen print. In the course of maintaining her laser this art student discovered a dramatically improved method for aligning the complex optical beam train by utilizing her artistic training. A few months later another CASS/UCSD student in the Photographic Arts Program (while modifying a ruby laser to experiment with theater-lighting special effects) discovered an improved laser beam-profile diagnostic technique. These two, seemingly trite, examples of scientific serendipity "in reverse" are not isolated anomalies. History is replete with instances of art coming to the aid of science and technology. Examples include Samuel Morse's drawing upon his skill as a painter in support of his electrical engineering research, the collaboration of Michele Besso and Albert Einstein in the formulation of Special Relativity, Picasso's vision of wave-function collapse in Quantum Electrodynamics, and Jay DeFeo's depiction of Big Bangs and Black Holes while cosmologists were focusing on Fred Hoyle's steady-state continuum theory of the universe.

Adaptation of the TH Epsilon Mu formalism for the analysis of the equivalence principle in the presence of the weak and electroweak interaction

NASA Technical Reports Server (NTRS)

Fennelly, A. J.

1981-01-01

The TH epsilon mu formalism, used in analyzing equivalence principle experiments of metric and nonmetric gravity theories, is adapted to the description of the electroweak interaction using the Weinberg-Salam unified SU(2) x U(1) model. The use of the TH epsilon mu formalism is thereby extended to the weak interactions, showing how the gravitational field affects W sub mu (+ or -1) and Z sub mu (0) boson propagation and the rates of interactions mediated by them. The possibility of a similar extension to the strong interactions via SU(5) grand unified theories is briefly discussed. Also, using the effects of the potentials on the baryon and lepton wave functions, the effects of gravity on transition mediated in high-A atoms which are electromagnetically forbidden. Three possible experiments to test the equivalence principle in the presence of the weak interactions, which are technologically feasible, are then briefly outline: (1) K-capture by the FE nucleus (counting the emitted X-ray); (2) forbidden absorption transitions in high-A atoms' vapor; and (3) counting the relative Beta-decay rates in a suitable alpha-beta decay chain, assuming the strong interactions obey the equivalence principle.

SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 1: Plenary Session

NASA Technical Reports Server (NTRS)

1991-01-01

Briefings from the plenary session of the conference on SSTAC/ARTS Review of the Draft Integrated Technology Plan (ITP) held on 24-28 Jun. 1991 are included. Viewgraphs from the presentations are included.

An analysis of integrated science and language arts themes in software at the elementary school level

NASA Astrophysics Data System (ADS)

Libidinsky, Lisa Jill

2002-09-01

There are many demands on the elementary classroom teacher today, such that teachers often do not have the time and resources to instruct in a meaningful manner that would produce effective, real instruction. Subjects are often disjointed and not significant. When teachers instruct using an integrated approach, students learn more efficiently as they see connections in the subjects. Science and language arts, when combined to produce an integrated approach, show positive associations that can enable students to learn real-life connections. In addition, with the onset of technology and the increased usage of technological programs in the schools, teachers can use technology to support an integrated curriculum. When teachers use a combined instructional focus of science, language arts, and technology to produce lessons, students are able to gain knowledge of concepts and skills necessary for appropriate academic growth and development. Given that there are many software programs available to teachers for classroom use, it is imperative that quality software is used for instruction. Using criteria based upon an intensive literature review of integrated instruction in the areas of science and language arts, this study examines science and language arts software programs to determine whether there are science and language arts integrated themes in the software analyzed. Also, this study examines whether more science and language arts integrated themes are present in science or language arts software programs. Overall, this study finds a significant difference between language arts software and science software when looking at integrated themes. This study shows that science software shows integrated themes with language arts more often than does language arts software with science. The findings in this study can serve as a reference point for educators when selecting software that is meaningful and effective in the elementary classroom. Based on this study, it is apparent that there is a need to evaluate software for appropriate use in the classroom in order to promote effective education.

A Curriculum Guide for Industrial Arts Plastic Technology. Intermediate and Secondary Level Students.

ERIC Educational Resources Information Center

Landers, Jack M.

This curriculum guide is an aid to administrators and instructors of industrial arts and vocational-technical school programs for the development of meaningful curriculum in plastics. The materials are intended for use at four levels: level I, exploring plastic technology; Level II, basic plastic technology; and levels III and IV, applied plastic…

Dynamic strain-mediated coupling of a single diamond spin to a mechanical resonator

NASA Astrophysics Data System (ADS)

Ovartchaiyapong, Preeti; Lee, Kenneth W.; Myers, Bryan A.; Jayich, Ania C. Bleszynski

2014-07-01

The development of hybrid quantum systems is central to the advancement of emerging quantum technologies, including quantum information science and quantum-assisted sensing. The recent demonstration of high-quality single-crystal diamond resonators has led to significant interest in a hybrid system consisting of nitrogen-vacancy centre spins that interact with the resonant phonon modes of a macroscopic mechanical resonator through crystal strain. However, the nitrogen-vacancy spin-strain interaction has not been well characterized. Here, we demonstrate dynamic, strain-mediated coupling of the mechanical motion of a diamond cantilever to the spin of an embedded nitrogen-vacancy centre. Via quantum control of the spin, we quantitatively characterize the axial and transverse strain sensitivities of the nitrogen-vacancy ground-state spin. The nitrogen-vacancy centre is an atomic scale sensor and we demonstrate spin-based strain imaging with a strain sensitivity of 3 × 10-6 strain Hz-1/2. Finally, we show how this spin-resonator system could enable coherent spin-phonon interactions in the quantum regime.

Communication Technology Use and mHealth Acceptance among HIV-infected Men who have Sex with Men in Peru: Implications for HIV Prevention and Treatment

PubMed Central

Krishnan, Archana; Ferro, Enrico G.; Weikum, Damian; Vagenas, Panagiotis; Lama, Javier R.; Sanchez, Jorge; Altice, Frederick L.

2014-01-01

The HIV epidemic in Peru is concentrated among men who have sex with men (MSM). Given that MSM have been documented as early adopters of emerging technology, we examined communication technology access and utilization, and mobile health (mHealth) acceptance among Peruvian MSM and transgender women (TGW) in order to gauge opportunities for mHealth-enabled HIV interventions. A convenience sample of 359 HIV-infected MSM and TGW recruited from three sites in Lima, Peru completed standardized assessments of alcohol use disorders (AUDs), risky sexual behavior, and antiretroviral therapy (ART) adherence along with self-constructed measures of communication technology access and utilization, and mHealth acceptance. Most (86%) participants had daily access to any cell phone, including smartphones (30%). The most frequent communication activities were receiving and making calls, and receiving and sending text messages using cell phones. On a 5-point Likert scale, participants expressed interest in using mHealth for medication reminders (M=3.21, SD=1.32) and engaging in anonymous online interactions with health professionals to discuss HIV-related issues (M=3.56, SD=1.33). Importantly, no significant differences were found in communication technology use and mHealth acceptance among participants with AUDs, depression and suboptimal ART adherence, all of which are associated with poor HIV treatment outcomes. Findings show support for implementing mHealth-based intervention strategies using cell phones to assess and reduce HIV-risk behaviors among HIV-infected MSM and TGW. PMID:25285464

ARV robotic technologies (ART): a risk reduction effort for future unmanned systems

NASA Astrophysics Data System (ADS)

Jaster, Jeffrey F.

2006-05-01

The Army's ARV (Armed Robotic Vehicle) Robotic Technologies (ART) program is working on the development of various technological thrusts for use in the robotic forces of the future. The ART program will develop, integrate and demonstrate the technology required to advance the maneuver technologies (i.e., perception, mobility, tactical behaviors) and increase the survivability of unmanned platforms for the future force while focusing on reducing the soldiers' burden by providing an increase in vehicle autonomy coinciding with a decrease in the total number user interventions required to control the unmanned assets. This program will advance the state of the art in perception technologies to provide the unmanned platform an increasingly accurate view of the terrain that surrounds it; while developing tactical/mission behavior technologies to provide the Unmanned Ground Vehicle (UGV) the capability to maneuver tactically, in conjunction with the manned systems in an autonomous mode. The ART testbed will be integrated with the advanced technology software and associated hardware developed under this effort, and incorporate appropriate mission modules (e.g. RSTA sensors, MILES, etc.) to support Warfighter experiments and evaluations (virtual and field) in a military significant environment (open/rolling and complex/urban terrain). The outcome of these experiments as well as other lessons learned through out the program life cycle will be used to reduce the current risks that are identified for the future UGV systems that will be developed under the Future Combat Systems (FCS) program, including the early integration of an FCS-like autonomous navigation system onto a tracked skid steer platform.

Merging the Internet and Hypermedia in the English Language Arts.

ERIC Educational Resources Information Center

Reed, W. Michael; Wells, John G.

1997-01-01

Discussion of hypermedia and computer-mediated communication focuses on a project that merges a language arts Internet resource with a hypermedia-based knowledge construction approach to learning. Highlights include constructing a HyperCard-based program on Shakespeare's "Hamlet," gophers and search engines, downloading, collaborative…

Beyond Art Waitressing: Meaningful Engagement in Interactive Art Galleries

ERIC Educational Resources Information Center

Kothe, Elsa Lenz

2012-01-01

The metaphor of "art waitressing" is a valuable tool for educators who seek guidance in enacting many of the new roles in museums, particularly the role of facilitator in an open-ended interactive gallery. Though this metaphor provides a valuable model for engaging visitors, the question quickly arises of how educators can go beyond "serving" an…

Failures of reproduction: problematising 'success' in assisted reproductive technology.

PubMed

Peters, Kathleen; Jackson, Debra; Rudge, Trudy

2007-06-01

This paper scrutinises the many ways in which 'success' is portrayed in representing assisted reproductive technology (ART) services and illuminates how these definitions differ from those held by participant couples. A qualitative approach informed by feminist perspectives guided this study and aimed to problematise the concept of 'success' by examining literature from ART clinics, government reports on ART, and by analysing narratives of couples who have accessed ART services. As many ART services have varying definitions of 'success' and as statistics are manipulated to promote further patronage of ART services, the likelihood of 'success' is often overstated. This paper is concerned with the effects this promotion has on the participants. We suggest that this very mobilisation of statistical success changes the ability of those who access ART services to make productive decisions about themselves inside these treatment regimes, as the basis for decision-making is hidden by the way numbers, objectivity and clinical reasoning operate to maintain participation in the program. In such an operation, the powerful mix of hope and technology kept participants enrolled far longer than they originally planned. Moreover, how success rates are manipulated raises ethical issues for all involved: clients, counsellors, and nursing and medical professionals.

Promoting Art through Technology, Education and Research of Natural Sciences (PATTERNS) across Wyoming, A Wyoming NSF EPSCoR Funded Project

NASA Astrophysics Data System (ADS)

Gellis, B. S.; McElroy, B. J.

2016-12-01

PATTERNS across Wyoming is a science and art project that promotes new and innovative approaches to STEM education and outreach, helping to re-contextualize how educators think about creative knowledge, and how to reach diverse audiences through informal education. The convergence of art, science and STEM outreach efforts is vital to increasing the presence of art in geosciences, developing multidisciplinary student research opportunities, expanding creative STEM thinking, and generating creative approaches of visualizing scientific data. A major goal of this project is to train art students to think critically about the value of scientific and artistic inquiry. PATTERNS across Wyoming makes science tangible to Wyoming citizens through K-14 art classrooms, and promotes novel maker-based art explorations centered around Wyoming's geosciences. The first PATTERNS across Wyoming scientific learning module (SIM) is a fish-tank sized flume that recreates natural patterns in sand as a result of fluid flow and sediment transport. It will help promotes the understanding of river systems found across Wyoming (e.g. Green, Yellowstone, Snake). This SIM, and the student artwork inspired by it, will help to visualize environmental-water changes in the central Rocky Mountains and will provide the essential inspiration and tools for Wyoming art students to design biological-driven creative explorations. Each art class will receive different fluvial system conditions, allowing for greater understanding of river system interactions. Artwork will return to the University of Wyoming for a STE{A}M Exhibition inspired by Wyoming's varying fluvial systems. It is our hope that new generations of science and art critical thinkers will not only explore questions of `why' and `how' scientific phenomena occur, but also `how' to better predict, conserve and study invaluable artifacts, and visualize conditions which allow for better control of scientific outcomes and public understanding.

A Review on Real-Time 3D Ultrasound Imaging Technology

PubMed Central

Zeng, Zhaozheng

2017-01-01

Real-time three-dimensional (3D) ultrasound (US) has attracted much more attention in medical researches because it provides interactive feedback to help clinicians acquire high-quality images as well as timely spatial information of the scanned area and hence is necessary in intraoperative ultrasound examinations. Plenty of publications have been declared to complete the real-time or near real-time visualization of 3D ultrasound using volumetric probes or the routinely used two-dimensional (2D) probes. So far, a review on how to design an interactive system with appropriate processing algorithms remains missing, resulting in the lack of systematic understanding of the relevant technology. In this article, previous and the latest work on designing a real-time or near real-time 3D ultrasound imaging system are reviewed. Specifically, the data acquisition techniques, reconstruction algorithms, volume rendering methods, and clinical applications are presented. Moreover, the advantages and disadvantages of state-of-the-art approaches are discussed in detail. PMID:28459067

A Review on Real-Time 3D Ultrasound Imaging Technology.

PubMed

Huang, Qinghua; Zeng, Zhaozheng

2017-01-01

Real-time three-dimensional (3D) ultrasound (US) has attracted much more attention in medical researches because it provides interactive feedback to help clinicians acquire high-quality images as well as timely spatial information of the scanned area and hence is necessary in intraoperative ultrasound examinations. Plenty of publications have been declared to complete the real-time or near real-time visualization of 3D ultrasound using volumetric probes or the routinely used two-dimensional (2D) probes. So far, a review on how to design an interactive system with appropriate processing algorithms remains missing, resulting in the lack of systematic understanding of the relevant technology. In this article, previous and the latest work on designing a real-time or near real-time 3D ultrasound imaging system are reviewed. Specifically, the data acquisition techniques, reconstruction algorithms, volume rendering methods, and clinical applications are presented. Moreover, the advantages and disadvantages of state-of-the-art approaches are discussed in detail.

Length of training, hostility and the martial arts: a comparison with other sporting groups.

PubMed Central

Daniels, K; Thornton, E

1992-01-01

Previous research has indicated that training in the martial arts leads to a reduction in levels of hostility. However, such research has only compared hostility within martial arts groups. The present research compares two martial arts groups and two other sporting groups on levels of assaultive, verbal and indirect hostility. Moderated multiple regression analyses revealed a significant interaction between length of training in the respondent's stated sport and whether that sport was a martial art in predicting assaultive and verbal hostility. The form of the interaction suggests that participation in the martial arts is associated, over time, with decreased feelings of assaultive and verbal hostility. PMID:1422642

Acceptability of a Virtual Patient Educator for Hispanic Women.

PubMed

Wells, Kristen J; Vàzquez-Otero, Coralia; Bredice, Marissa; Meade, Cathy D; Chaet, Alexis; Rivera, Maria I; Arroyo, Gloria; Proctor, Sara K; Barnes, Laura E

2015-01-01

There are few Spanish language interactive, technology-driven health education programs. Objectives of this feasibility study were to (a) learn more about computer and technology usage among Hispanic women living in a rural community and (b) evaluate acceptability of the concept of using an embodied conversational agent (ECA) computer application among this population. A survey about computer usage history and interest in computers was administered to a convenience sample of 26 women. A sample video prototype of a hospital discharge ECA was administered followed by questions to gauge opinion about the ECA. Data indicate women exhibited both a high level of computer experience and enthusiasm for the ECA. Feedback from community is essential to ensure equity in state of the art dissemination of health information.

MagLev Cobra: Test Facilities and Operational Experiments

NASA Astrophysics Data System (ADS)

Sotelo, G. G.; Dias, D. H. J. N.; de Oliveira, R. A. H.; Ferreira, A. C.; De Andrade, R., Jr.; Stephan, R. M.

2014-05-01

The superconducting MagLev technology for transportation systems is becoming mature due to the research and developing effort of recent years. The Brazilian project, named MagLev-Cobra, started in 1998. It has the goal of developing a superconducting levitation vehicle for urban areas. The adopted levitation technology is based on the diamagnetic and the flux pinning properties of YBa2Cu3O7-δ (YBCO) bulk blocks in the interaction with Nd-Fe-B permanent magnets. A laboratory test facility with permanent magnet guideway, linear induction motor and one vehicle module is been built to investigate its operation. The MagLev-Cobra project state of the art is presented in the present paper, describing some construction details of the new test line with 200 m.

Is Technology-Mediated Parental Monitoring Related to Adolescent Substance Use?

PubMed

Rudi, Jessie; Dworkin, Jodi

2018-01-03

Prevention researchers have identified parental monitoring leading to parental knowledge to be a protective factor against adolescent substance use. In today's digital society, parental monitoring can occur using technology-mediated communication methods, such as text messaging, email, and social networking sites. The current study aimed to identify patterns, or clusters, of in-person and technology-mediated monitoring behaviors, and examine differences between the patterns (clusters) in adolescent substance use. Cross-sectional survey data were collected from 289 parents of adolescents using Facebook and Amazon Mechanical Turk (MTurk). Cluster analyses were computed to identify patterns of in-person and technology-mediated monitoring behaviors, and chi-square analyses were computed to examine differences in substance use between the identified clusters. Three monitoring clusters were identified: a moderate in-person and moderate technology-mediated monitoring cluster (moderate-moderate), a high in-person and high technology-mediated monitoring cluster (high-high), and a high in-person and low technology-mediated monitoring cluster (high-low). Higher frequency of technology-mediated parental monitoring was not associated with lower levels of substance use. Results show that higher levels of technology-mediated parental monitoring may not be associated with adolescent substance use.

Art Education and Rural Schools: Reflections from the Field. Country Teacher.

ERIC Educational Resources Information Center

Thurber, Frances E.

1997-01-01

An art education teacher-educator discusses the strengths and potential of rural education, arising from the sense of community found in small rural schools. Gives six suggestions to art teacher-educators concerning integrating art with other curricula, utilizing technology in art education, ensuring that rural students are afforded equal…

Imprinting Disorders and Assisted Reproductive Technology

PubMed Central

Owen, Carter M.; Segars, James H.

2009-01-01

Worldwide use of assisted reproductive technology (ART) accounts for an estimated 1 to 3% of births. Since 2002, a series of reports have suggested an increased risk of imprinting disorders (Beckwith-Wiedemann syndrome and Angelman syndrome) in children conceived by ART. Definitive conclusions are difficult to substantiate due to the rarity of imprinting disorders and the variability in ART protocols. Despite these limitations, there is biological plausibility for alteration in nongenomic inheritance caused by ART. Animal studies have shown that ART procedures can alter normal imprinting, specifically DNA methylation patterns. Collectively, studies suggest an association between ART and loss of maternal methylation. More recent reports examined a possible association between ART and global hypomethylation of DNA. Three other imprinting disorders (Silver-Russell syndrome, maternal hypomethylation syndrome, and retinoblastoma) have also been implicated, but there is insufficient evidence to establish an association of these syndromes with ART. Based on current evidence, the absolute risk of imprinting disorders after ART remains small and does not warrant routine screening. Large prospective studies are needed to better understand the risks associated with imprinting disorders, imprinting defects, and ART. PMID:19711252

Ergonomic aspects of a virtual environment.

PubMed

Ahasan, M R; Väyrynen, S

1999-01-01

A virtual environment is an interactive graphic system mediated through computer technology that allows a certain level of reality or a sense of presence to access virtual information. To create reality in a virtual environment, ergonomics issues are explored in this paper, aiming to develop the design of presentation formats with related information, that is possible to attain and to maintain user-friendly application.

Reconceptualising Understandings of Texts, Readers and Contexts: One English Teacher's Response to Using Multimodal Texts and Interactive Whiteboards

ERIC Educational Resources Information Center

Kitson, Lisbeth

2011-01-01

The comprehension of multimodal texts is now a key concern with the release of the Australian National Curriculum for English (ACARA, 2010). However, the nature of multimodal texts, the diversity of readers in classrooms, and the complex technological environments through which multimodal texts are mediated, requires English teachers to reconsider…

How Drawing Is Taught in Chinese Infant Schools

ERIC Educational Resources Information Center

Jolley, Richard; Zhang, Zhi

2012-01-01

The benefits of drawing for children are wide-ranging but are likely to be mediated by the art curriculum and other governmental guidance to teachers relevant to drawing/art. Furthermore, such statutory regulations vary between cultures, and therefore curricula represent an important influence on the cultural differences found in children's…

Technology addiction's contribution to mental wellbeing: The positive effect of online social capital.

PubMed

Magsamen-Conrad, Kate; Billotte-Verhoff, China; Greene, Kathryn

2014-11-01

This research examines the effect of online social capital and Internet use on the normally negative effects of technology addiction, especially for individuals prone to self-concealment. Self-concealment is a personality trait that describes individuals who are more likely to withhold personal and private information, inhibiting catharsis and wellbeing. Addiction, in any context, is also typically associated with negative outcomes. However, we investigate the hypothesis that communication technology addiction may positively affect wellbeing for self-concealing individuals when online interaction is positive, builds relationships, or fosters a sense of community. Within these parameters, increased communication through mediated channels (and even addiction) may reverse the otherwise negative effects of self-concealment on wellbeing. Overall, the proposed model offers qualified support for the continued analysis of mediated communication as a potential source for improving the wellbeing for particular individuals. This study is important because we know that healthy communication in relationships, including disclosure, is important to wellbeing. This study recognizes that not all people are comfortable communicating in face-to-face settings. Our findings offer evidence that the presence of computers in human behaviors (e.g., mediated channels of communication and NCTs) enables some individuals to communicate and fos ter beneficial interpersonal relationships, and improve their wellbeing.

Technology addiction's contribution to mental wellbeing: The positive effect of online social capital

PubMed Central

Magsamen-Conrad, Kate; Billotte-Verhoff, China; Greene, Kathryn

2014-01-01

This research examines the effect of online social capital and Internet use on the normally negative effects of technology addiction, especially for individuals prone to self-concealment. Self-concealment is a personality trait that describes individuals who are more likely to withhold personal and private information, inhibiting catharsis and wellbeing. Addiction, in any context, is also typically associated with negative outcomes. However, we investigate the hypothesis that communication technology addiction may positively affect wellbeing for self-concealing individuals when online interaction is positive, builds relationships, or fosters a sense of community. Within these parameters, increased communication through mediated channels (and even addiction) may reverse the otherwise negative effects of self-concealment on wellbeing. Overall, the proposed model offers qualified support for the continued analysis of mediated communication as a potential source for improving the wellbeing for particular individuals. This study is important because we know that healthy communication in relationships, including disclosure, is important to wellbeing. This study recognizes that not all people are comfortable communicating in face-to-face settings. Our findings offer evidence that the presence of computers in human behaviors (e.g., mediated channels of communication and NCTs) enables some individuals to communicate and fos ter beneficial interpersonal relationships, and improve their wellbeing. PMID:25568591

New Technology/Assistive Technology and the Arts. Proceedings of the National Institute, July 29--August 1, 1991.

ERIC Educational Resources Information Center

Peterson, Charles R., Ed.

This document is prefaced with a descriptive introduction to the "Access to the Arts Through Assistive Technology Project." The contents that follow are organized in 5 parts. Part 1 includes: "Introduction" (Betsy Foley), and "My Voice Has Wings" (Jeff Moyer). Part 2, "Major Addresses," presents: (1) "Welcome from the Wisconsin Department of…

A Study of the Integrated Alignment of Technology and Organizational Strategic Planning in Small Private Liberal Arts Colleges and Universities

ERIC Educational Resources Information Center

Schneider, Sheree A.

2010-01-01

The purpose of this study was to determine the relationship between technology planning and strategic planning in small private liberal arts colleges and universities that were members of the Appalachian College Association (ACA). The objective of the study was to determine if the technology initiatives were appropriately aligned to the…

Moving from Industrial Arts to Living Technology: The Status of Technology Education in Taiwan, R.O.C.

ERIC Educational Resources Information Center

Lee, Lung-Sheng Steven

In Taiwan, technology education has traditionally been covered by two courses: Craftwork and Industrial Arts (IA). At present, all students in grades 1-6 take Craftwork. At the junior and senior high school levels, IA is considered a subordinate subject, and students must elect IA or home economics. In accordance with Taiwan's new national…

Endocytosis of the Aspartic Acid/Glutamic Acid Transporter Dip5 Is Triggered by Substrate-Dependent Recruitment of the Rsp5 Ubiquitin Ligase via the Arrestin-Like Protein Aly2 ▿

PubMed Central

Hatakeyama, Riko; Kamiya, Masao; Takahara, Terunao; Maeda, Tatsuya

2010-01-01

Endocytosis of nutrient transporters is stimulated under various conditions, such as elevated nutrient availability. In Saccharomyces cerevisiae, endocytosis is triggered by ubiquitination of transporters catalyzed by the E3 ubiquitin ligase Rsp5. However, how the ubiquitination is accelerated under certain conditions remains obscure. Here we demonstrate that closely related proteins Aly2/Art3 and Aly1/Art6, which are poorly characterized members of the arrestin-like protein family, mediate endocytosis of the aspartic acid/glutamic acid transporter Dip5. In aly2Δ cells, Dip5 is stabilized at the plasma membrane and is not endocytosed efficiently. Efficient ubiquitination of Dip5 is dependent on Aly2. aly1Δ cells also show deficiency in Dip5 endocytosis, although less remarkably than aly2Δ cells. Aly2 physically interacts in vivo with Rsp5 at its PY motif and also with Dip5, thus serving as an adaptor linking Rsp5 with Dip5 to achieve Dip5 ubiquitination. Importantly, the interaction between Aly2 and Dip5 is accelerated in response to elevated aspartic acid availability. This result indicates that the regulation of Dip5 endocytosis is accomplished by dynamic recruitment of Rsp5 via Aly2. PMID:20956561

Crush-2: Communicating research through a science-art collaboration

NASA Astrophysics Data System (ADS)

Mair, K.; Barrett, N.; Schubnel, A. J.; Abe, S.

2011-12-01

Historically, the Earth's environment and dynamics have influenced and inspired the arts. Art in turn is a powerful vehicle for expression of the natural world. It lends itself to public presentation in many forms and appeals to a diverse audience. Science-art collaborations provide a unique opportunity to connect with the public by taking science out of the classroom and into museums, galleries and public spaces. Here we investigate the use of contemporary digital sound-art in communicating geoscience research to the general public through the installation Crush-2. Crush-2, is an interactive sound-art installation exploring the microscopic forces released during the crushing of rock. Such processes have a strong influence on the sliding behaviour and hence earthquake potential of active faults. This work is a collaboration between sound artist and composer Natasha Barrett (Oslo) and geoscientists Karen Mair (University of Oslo), Alexandre Schubnel (Ecole Normale Superieure, Paris) and Steffen Abe (RWTH Aachen). Using a sonification technique, Barrett has assigned sound recorded from rocks, of different pitches, timbres and durations, to individual fracturing events produced in our 3D fault fragmentation models and laboratory rock breaking experiments. In addition, ultrasonic acoustic emissions recorded directly in the laboratory are made audible for our hearing and feature in the work. The installation space comprises a loudspeaker array and sensor enabled helmet with wireless headphones. By wearing the helmet, moving and listening, the audience explores an artistic interpretation of the scientific data in physical space. On entering the space, one is immediately immersed in a 3D cacophony of sound. Sustained or intermittent pings, burrs, plops and tingles jostle for position in our heads whilst high pitched delicate cascades juxtapose with deep thunder like rumbles. Depending on the user's precise path through the soundscape, the experience changes accordingly, so every visitor has a unique sound adventure. The experience is intensely engaging, playful and yet a little unsettling and provides a truly unique way to explore our scientific data and present geoscience research to the public. Crush-2 has featured in an exhibition on Sonic Interaction Design at the Norwegian Museum of Science, Technology and Medicine, Oslo, Norway (27 May - 21 August 2011) and forms part of a solo exhibition by Barrett at Galleri ROM, Oslo in fall 2011. Visitor feedback from the Museum exhibition suggests that users were initially attracted to the exhibit by its interactive 'hands-on' nature and dramatic sounds, but as they 'explored' the soundspace, became curious to ask questions about the underlying science. The concept of using sound rather than visual gives an unusual and therefore highly memorable experience. This science-art collaboration provides a novel and highly enjoyable way to present our work to the public - that is particularly attractive to youngsters. Visitors to this poster presentation will be able to explore the Crush-2 soundscape using a laptop and headphone interactive mode.

Art, Technology, and the Holy: Reflections on the Work of J. M. W. Turner

ERIC Educational Resources Information Center

Murray, Michael

1974-01-01

The following reflections focus on one of the late works by Turner, Rain, Steam, and Speed: The Great Western Railway (1844), and its possible bearing on the three-fold theme of art, technology, and the holy. (Author)

Professional Development Needs as Perceived by Minnesota Industrial Arts/Technology Teachers.

ERIC Educational Resources Information Center

Johnson, Scott D.; Summers, Keith

1984-01-01

Describes a profile of professional development needs that was developed through a survey of 150 industrial arts/technology teachers in Minnesota. The greatest need was in the area of job environment: salary, job security, facilities and equipment, and discipline. (SK)

State-of-the-art technologies for intrusion and obstacle detection for railroad operations

DOT National Transportation Integrated Search

2007-07-01

This report provides an update on the state-of-the-art technologies with intrusion and obstacle detection capabilities for rail rights of way (ROW) and crossings. A workshop entitled Intruder and Obstacle Detection Systems (IODS) for Railroads Requir...

Mine Burial Assessment State-of the Art in Prediction and Modeling Workshop and Initiation of Technical Program

DTIC Science & Technology

2000-09-30

Burial Assessment State-of-the Art Science , Technology, and Modeling. A Review of Coastal Research, Modeling, and Naval Operational Needs in Shallow Water...the ONR Mine Burial Prediction Program are summarized below. 1) Completed comprehensive technical reports: a. Mine Burial Assessment, State-of-the Art ... Science , Technology, and Modeling. A review of Coastal Research, Modeling, and Naval Operational Needs in Shallow Water Environments with

Virtual Tour Environment of Cuba's National School of Art

NASA Astrophysics Data System (ADS)

Napolitano, R. K.; Douglas, I. P.; Garlock, M. E.; Glisic, B.

2017-08-01

Innovative technologies have enabled new opportunities for collecting, analyzing, and sharing information about cultural heritage sites. Through a combination of two of these technologies, spherical imaging and virtual tour environment, we preliminarily documented one of Cuba's National Schools of Art, the National Ballet School.The Ballet School is one of the five National Art Schools built in Havana, Cuba after the revolution. Due to changes in the political climate, construction was halted on the schools before completion. The Ballet School in particular was partially completed but never used for the intended purpose. Over the years, the surrounding vegetation and environment have started to overtake the buildings; damages such as missing bricks, corroded rebar, and broken tie bars can be seen. We created a virtual tour through the Ballet School which highlights key satellite classrooms and the main domed performance spaces. Scenes of the virtual tour were captured utilizing the Ricoh Theta S spherical imaging camera and processed with Kolor Panotour virtual environment software. Different forms of data can be included in this environment in order to provide a user with pertinent information. Image galleries, hyperlinks to websites, videos, PDFs, and links to databases can be embedded within the scene and interacted with by a user. By including this information within the virtual tour, a user can better understand how the site was constructed as well as the existing types of damage. The results of this work are recommendations for how a site can be preliminarily documented and information can be initially organized and shared.

Integrated human-machine intelligence in space systems

NASA Technical Reports Server (NTRS)

Boy, Guy A.

1992-01-01

The integration of human and machine intelligence in space systems is outlined with respect to the contributions of artificial intelligence. The current state-of-the-art in intelligent assistant systems (IASs) is reviewed, and the requirements of some real-world applications of the technologies are discussed. A concept of integrated human-machine intelligence is examined in the contexts of: (1) interactive systems that tolerate human errors; (2) systems for the relief of workloads; and (3) interactive systems for solving problems in abnormal situations. Key issues in the development of IASs include the compatibility of the systems with astronauts in terms of inputs/outputs, processing, real-time AI, and knowledge-based system validation. Real-world applications are suggested such as the diagnosis, planning, and control of enginnered systems.

History of Assisted Reproductive Technology and Chlamydia Trachomatis Infection in Pregnancy.

PubMed

Kato, Masahiko; Suzuki, Shunji

2016-03-01

To identify whether or not a history of assisted reproductive technology (ART) is associated with the low incidence of Chlamydia trachomatis (CT) infection in pregnant women, we reviewed the obstetric records of the Japanese women aged 35 - 42 years. The prevalence of CT in the pregnancies without ART was 1.1% (28/2,632) using nucleic acid amplification tests, while it was zero in the pregnancies conceived by ART (0/364, P = 0.049 by the X(2) test). A history of ART seemed to be a negative risk factor for CT infection in pregnant women.

Merging arts and bioethics: An interdisciplinary experiment in cultural and scientific mediation.

PubMed

Couture, Vincent; Bélisle-Pipon, Jean-Christophe; Cloutier, Marianne; Barnabé, Catherine

2017-10-01

How to engage the public in a reflection on the most pressing ethical issues of our time? What if part of the solution lies in adopting an interdisciplinary and collaborative strategy to shed light on critical issues in bioethics? An example is Art + Bioéthique, an innovative project that brought together bioethicists, art historians and artists with the aim of expressing bioethics through arts in order to convey the "sensitive" aspect of many health ethics issues. The aim of this project was threefold: 1) to identify and characterize mechanisms for the meeting of arts and bioethics; 2) to experiment with and co-construct a dialogue between arts and bioethics; and 3) to initiate a public discussion on bioethical issues through the blending of arts and bioethics. In connection with an exhibition held in March 2016 at the Espace Projet, a non-profit art space in Montréal (Canada), the project developed a platform that combined artworks, essays and cultural & scientific mediation activities related to the work of six duos of young bioethics researchers and emerging artists. Each duo worked on a variety of issues, such as the social inclusion of disabled people, the challenges of practical applications of nanomedicine and regenerative medicine, and a holistic approach to contemporary diseases. This project, which succeeded in stimulating an interdisciplinary dialogue and collaboration between bioethics and arts, is an example of an innovative approach to knowledge transfer that can move bioethics reflection into the public space. © 2017 John Wiley & Sons Ltd.

Advancing "Media Arts" Education in "Visual Arts" Classrooms: Addressing Policy Ambiguities and Gaps in Art Teacher Preparation

ERIC Educational Resources Information Center

Bequette, James W.; Brennan, Colleen

2008-01-01

Since the mid-1980s, arts policymakers in Minnesota have positioned "media arts"--defined as the "study and practice of examining human communication through photography, film or video, audio, computer or digital arts, and interactive media"--within the realm of aesthetic education and considered it one of six arts areas. This…

Technology as the Crayon Box.

ERIC Educational Resources Information Center

Garcia, Lilia

2000-01-01

While arts facilities should be equipped with computers, color scanners, MIDI (Musical Instrument Digital Interface) labs, connective video cameras, and appropriate software, music rooms still need pianos and visual art rooms need traditional art supplies. Dade County (Florida) Schools's pilot teacher assistance projects and arts-centered schools…

Childhood outcomes of assisted reproductive technology.

PubMed

Savage, Tim; Peek, John; Hofman, Paul L; Cutfield, Wayne S

2011-09-01

There is a large population of children conceived via assisted reproductive technology (ART), which continues to increase worldwide, without a clear understanding of associated long-term outcomes. ART children are more likely to be the result of multiple pregnancies, and thus to be born prematurely or low birthweight. There is growing evidence that ART children are phenotypically and biochemically different from naturally conceived children, but the mechanism(s) leading to these changes have not been elucidated. There is a possible increased risk of rare imprinted gene disorders in these children. However, it remains unclear whether more subtle changes in DNA methylation occur commonly, leading to differences in gene expression and phenotype in ART children. Although an increased risk of cancer among ART children has been reported, the role of ART in the development of cancer has not been demonstrated. Further research and ongoing surveillance of ART children is essential to better understand the possible effects of ART on the long-term health of this population.

The art of the chart note in clinical ethics consultation and bioethics mediation: conveying information that can be understood and evaluated.

PubMed

Dubler, Nancy Neveloff

2013-01-01

Unlike bioethics mediators who are employed by healthcare organizations as outside consultants, mediators who are embedded in an institution must be authorized to chronicle a clinical ethics consultation (CEC) or a mediation in a patient's medical chart. This is an important privilege, as the chart is a legal document. In this article I discuss this important part of a bioethics mediator's tool kit in my presentation of a case illustrating how bioethics mediation may proceed, and what this approach using both bioethics and mediation may add.

Investigational treatment suspension and enhanced cell-mediated immunity at rebound followed by drug-free remission of simian AIDS

PubMed Central

2013-01-01

Background HIV infection persists despite antiretroviral treatment (ART) and is reignited as soon as therapies are suspended. This vicious cycle is fueled by the persistence of viral reservoirs that are invulnerable to standard ART protocols, and thus therapeutic agents able to target these reservoirs are needed. One such agent, auranofin, has recently been shown to decrease the memory T-cell reservoir in chronically SIVmac251-infected macaques. Moreover, auranofin could synergize with a fully suppressive ART protocol and induce a drug-free post-therapy containment of viremia. Results We administered buthionine sulfoximine (BSO), an inhibitor of glutathione synthesis currently in clinical trials for cancer, in combination with auranofin to chronically SIVmac251-infected macaques under highly-intensified ART (H-iART). The ART/auranofin/BSO therapeutic protocol was followed, after therapy suspension, by a significant decrease of viral RNA and DNA in peripheral blood as compared to pre-therapy levels. Drug-free post-therapy control of the infection was achieved in animals with pre-therapy viral loads ranging from values comparable to average human set points to levels largely higher. This control was dependent on the presence CD8+ cells and associated with enhanced levels of cell-mediated immune responses. Conclusions The level of post-therapy viral set point reduction achieved in this study is the largest reported so far in chronically SIVmac251-infected macaques and may represent a promising strategy to improve over the current “ART for life” plight. PMID:23866829

Intercultural and Media Education on Art Classes

ERIC Educational Resources Information Center

Borges, Maria José; Chaves, Anabela; Costa, Manuela; Pereira, Emília Sá

2009-01-01

Visual art, music and literature, are part of the culture. Thus Art shows the interactions between different cultures. The aim of the article is to present some activities to include intercultural issues in Art and Mother Language classes. Art classes also give the opportunity to do Media Education.

Assessment of the State of the Art of Flight Control Technologies as Applicable to Adverse Conditions

NASA Technical Reports Server (NTRS)

Reveley, Mary s.; Briggs, Jeffrey L.; Leone, Karen M.; Kurtoglu, Tolga; Withrow, Colleen A.

2010-01-01

Literature from academia, industry, and other Government agencies was surveyed to assess the state of the art in current Integrated Resilient Aircraft Control (IRAC) aircraft technologies. Over 100 papers from 25 conferences from the time period 2004 to 2009 were reviewed. An assessment of the general state of the art in adaptive flight control is summarized first, followed by an assessment of the state of the art as applicable to 13 identified adverse conditions. Specific areas addressed in the general assessment include flight control when compensating for damage or reduced performance, retrofit software upgrades to flight controllers, flight control through engine response, and finally test and validation of new adaptive controllers. The state-of-the-art assessment applicable to the adverse conditions include technologies not specifically related to flight control, but may serve as inputs to a future flight control algorithm. This study illustrates existing gaps and opportunities for additional research by the NASA IRAC Project

Communications Arts and Technology Program Needs Assessment.

ERIC Educational Resources Information Center

Oakland Community Coll., Farmington, MI. Office of Institutional Planning and Analysis.

In 1992, Oakland Community College conducted a needs assessment study to assist in reviewing and evaluating proposed changes to the college's existing Communications Arts and Technology Program. Businesses and employers in the communications field were surveyed (n=40) regarding employment requirements and opportunities. Additional information was…

Printing/Graphic Arts Technology Program Guide.

ERIC Educational Resources Information Center

Georgia Univ., Athens. Dept. of Vocational Education.

This guide presents the standard curriculum for technical institutes in Georgia. The curriculum addresses the minimum competencies for a printing/graphics technology program. It includes specializations in art and copy preparation, prepress/image assembly, and lithographic press operations. The guide contains four major sections. The General…

Tilt Train Technology : A State of the Art Survey

DOT National Transportation Integrated Search

1992-05-01

This report presents an overview of the state-of-the-art in tilt-train technology. It is intended to give the reader a better understanding of the unique features of this approach to train design and the variations that exist. Briefly described is th...

Advancing the art and science of dietary assessment through technology

USDA-ARS?s Scientific Manuscript database

This research editorial presents the background against which dietitians may consider the benefits of new technology being incorporated into the art and science of dietary assessment. The background provides past changes that have increased the need for computer applications being developed for indi...

Reading, Language Arts & Literacy.

ERIC Educational Resources Information Center

Matthew, Kathy, Ed.

This document contains the following papers on educational technology issues related to reading, language arts, and literacy: (1) "The Infusion of Technology into a Teacher Education Course: Issues and Strategies" (Mary Ann Kolloff); (2) "Project READ: Developing Online Course Materials for a Reading Methods Class" (Judith A.…

The Palazzo della Ragione in Padua: Representation and Communication of Art, Architecture, and Astrology of a Civic Monument

NASA Astrophysics Data System (ADS)

Borgherini, M.; Garbin, E.

2011-06-01

Eight centuries of the history of art and of Padua's scientific and technological culture deposited on the stones and frescoes of its Palace of Law ("Palazzo della Ragione") make this great work of urban architecture a part of the city's collective identity. This "palimpsest", legible only to a restricted circle of specialists, should be accessible to a vaster public interested in understanding this object symbol of local culture. The project planned for interactive exploration on the web is a series of digital models, employing tomographic-endoscopic visualizations and, in future, multi-resolution images. The various models devised allow the visitor to superimpose the Palace's current conditions on the various transformations undergone over the centuries. Similarly, comparisons can be made between the astrological fresco cycle with maps of the heavens, cosmological hypotheses, ancient and contemporary astrological treatises, and the related exchange of knowledge between the Orient and the Occident.

Design and Decorative Art in Shaping of Architectural Environment Image

NASA Astrophysics Data System (ADS)

Shabalina, N. M.

2017-11-01

The relevance of the topic is determined by the dynamic development of the promising branch, i.e. the architectural environment design, which requires, on the one hand, consideration of the morphology and typology of this art form, on the other hand, the specificity of the architectural environment artistic image. The intensive development of innovative computer technologies and materials in modern engineering, improvement of the information communications forms in their totality has led to the application of new methods in design and construction which, in their turn, have required the development of additional methods for content and context analysis in the integrated assessment of socially significant architectural environments. In the modern culture, correlative processes are steadily developing leading us to a new understanding of the interaction of architecture, decorative art and design. Their rapprochement at the morphological level has been noted which makes it possible to reveal a specific method of synthesis and similarity. The architecture of postmodern styles differs in its bionic form becoming an interactive part of the society and approaching its structural qualities with painting, sculpture, and design. In the modern world, these processes acquire multi-valued semantic nuances, expand the importance of associativity and dynamic processuality in the perception of environmental objects and demand the development of new approaches to the assessment of the architectural design environment. Within the framework of the universal paradigm of modern times the concept of the world develops as a set of systems that live according to the self-organization laws.

The Brainarium: An Interactive Immersive Tool for Brain Education, Art, and Neurotherapy

PubMed Central

2016-01-01

Recent theoretical and technological advances in neuroimaging techniques now allow brain electrical activity to be recorded using affordable and user-friendly equipment for nonscientist end-users. An increasing number of educators and artists have begun using electroencephalogram (EEG) to control multimedia and live artistic contents. In this paper, we introduce a new concept based on brain computer interface (BCI) technologies: the Brainarium. The Brainarium is a new pedagogical and artistic tool, which can deliver and illustrate scientific knowledge, as well as a new framework for scientific exploration. The Brainarium consists of a portable planetarium device that is being used as brain metaphor. This is done by projecting multimedia content on the planetarium dome and displaying EEG data recorded from a subject in real time using Brain Machine Interface (BMI) technologies. The system has been demonstrated through several performances involving an interaction between the subject controlling the BMI, a musician, and the audience during series of exhibitions and workshops in schools. We report here feedback from 134 participants who filled questionnaires to rate their experiences. Our results show improved subjective learning compared to conventional methods, improved entertainment value, improved absorption into the material being presented, and little discomfort. PMID:27698660

Control-Structure-Interaction (CSI) technologies and trends to future NASA missions

NASA Technical Reports Server (NTRS)

1990-01-01

Control-structure-interaction (CSI) issues which are relevant for future NASA missions are reviewed. This goal was achieved by: (1) reviewing large space structures (LSS) technologies to provide a background and survey of the current state of the art (SOA); (2) analytically studying a focus mission to identify opportunities where CSI technology may be applied to enhance or enable future NASA spacecraft; and (3) expanding a portion of the focus mission, the large antenna, to provide in-depth trade studies, scaling laws, and methodologies which may be applied to other NASA missions. Several sections are presented. Section 1 defines CSI issues and presents an overview of the relevant modeling and control issues for LLS. Section 2 presents the results of the three phases of the CSI study. Section 2.1 gives the results of a CSI study conducted with the Geostationary Platform (Geoplat) as the focus mission. Section 2.2 contains an overview of the CSI control design methodology available in the technical community. Included is a survey of the CSI ground-based experiments which were conducted to verify theoretical performance predictions. Section 2.3 presents and demonstrates a new CSI scaling law methodology for assessing potential CSI with large antenna systems.

Revitalizing the Physics Department: The Use of Interactive Technologies to Improve Student Learning

NASA Astrophysics Data System (ADS)

Sheldon, Peter; Groover, Holly

2002-04-01

The Physics Department at Randolph-Macon Woman's College, a liberal arts women's college of 720, has traditionally turned out approximately 0.6 majors/year. We have invigorated the program by adding community (e.g. SPS, physical space, organized activities), adding a significant technical component (e.g. web-assisted and computerized labs and more technology in the classes [1]), and incorporating new learning techniques (JITT, Physlets, Peer Instruction and Cooperative Learning [2]). Students have responded well as evidenced by significant increases in enrollments as well as strong scores on the FCI. We have seen mixed results in the lab, but increased performance in the class, which is attributed to the interactive learning techniques that are being implemented through new technologies. In this presentation, we will discuss the implementation of the new curricular developments and the specific changes we have seen in student learning. [1] This work is supported in part by the NSF CCLI Program under grant DUE-9980890. Additional support has been from the Virginia Foundation of Private Colleges and AT&T. [2] See, for example, the project Galileo website http://galileo.harvard.edu for a description of all of these techniques.

The Brainarium: An Interactive Immersive Tool for Brain Education, Art, and Neurotherapy.

PubMed

Grandchamp, Romain; Delorme, Arnaud

2016-01-01

Recent theoretical and technological advances in neuroimaging techniques now allow brain electrical activity to be recorded using affordable and user-friendly equipment for nonscientist end-users. An increasing number of educators and artists have begun using electroencephalogram (EEG) to control multimedia and live artistic contents. In this paper, we introduce a new concept based on brain computer interface (BCI) technologies: the Brainarium. The Brainarium is a new pedagogical and artistic tool, which can deliver and illustrate scientific knowledge, as well as a new framework for scientific exploration. The Brainarium consists of a portable planetarium device that is being used as brain metaphor. This is done by projecting multimedia content on the planetarium dome and displaying EEG data recorded from a subject in real time using Brain Machine Interface (BMI) technologies. The system has been demonstrated through several performances involving an interaction between the subject controlling the BMI, a musician, and the audience during series of exhibitions and workshops in schools. We report here feedback from 134 participants who filled questionnaires to rate their experiences. Our results show improved subjective learning compared to conventional methods, improved entertainment value, improved absorption into the material being presented, and little discomfort.

The NASA Augmented/Virtual Reality Lab: The State of the Art at KSC

NASA Technical Reports Server (NTRS)

Little, William

2017-01-01

The NASA Augmented Virtual Reality (AVR) Lab at Kennedy Space Center is dedicated to the investigation of Augmented Reality (AR) and Virtual Reality (VR) technologies, with the goal of determining potential uses of these technologies as human-computer interaction (HCI) devices in an aerospace engineering context. Begun in 2012, the AVR Lab has concentrated on commercially available AR and VR devices that are gaining in popularity and use in a number of fields such as gaming, training, and telepresence. We are working with such devices as the Microsoft Kinect, the Oculus Rift, the Leap Motion, the HTC Vive, motion capture systems, and the Microsoft Hololens. The focus of our work has been on human interaction with the virtual environment, which in turn acts as a communications bridge to remote physical devices and environments which the operator cannot or should not control or experience directly. Particularly in reference to dealing with spacecraft and the oftentimes hazardous environments they inhabit, it is our hope that AR and VR technologies can be utilized to increase human safety and mission success by physically removing humans from those hazardous environments while virtually putting them right in the middle of those environments.

Advantages of mixing bioinformatics and visualization approaches for analyzing sRNA-mediated regulatory bacterial networks

PubMed Central

Bourqui, Romain; Benchimol, William; Gaspin, Christine; Sirand-Pugnet, Pascal; Uricaru, Raluca; Dutour, Isabelle

2015-01-01

The revolution in high-throughput sequencing technologies has enabled the acquisition of gigabytes of RNA sequences in many different conditions and has highlighted an unexpected number of small RNAs (sRNAs) in bacteria. Ongoing exploitation of these data enables numerous applications for investigating bacterial transacting sRNA-mediated regulation networks. Focusing on sRNAs that regulate mRNA translation in trans, recent works have noted several sRNA-based regulatory pathways that are essential for key cellular processes. Although the number of known bacterial sRNAs is increasing, the experimental validation of their interactions with mRNA targets remains challenging and involves expensive and time-consuming experimental strategies. Hence, bioinformatics is crucial for selecting and prioritizing candidates before designing any experimental work. However, current software for target prediction produces a prohibitive number of candidates because of the lack of biological knowledge regarding the rules governing sRNA–mRNA interactions. Therefore, there is a real need to develop new approaches to help biologists focus on the most promising predicted sRNA–mRNA interactions. In this perspective, this review aims at presenting the advantages of mixing bioinformatics and visualization approaches for analyzing predicted sRNA-mediated regulatory bacterial networks. PMID:25477348

Advantages of mixing bioinformatics and visualization approaches for analyzing sRNA-mediated regulatory bacterial networks.

PubMed

Thébault, Patricia; Bourqui, Romain; Benchimol, William; Gaspin, Christine; Sirand-Pugnet, Pascal; Uricaru, Raluca; Dutour, Isabelle

2015-09-01

The revolution in high-throughput sequencing technologies has enabled the acquisition of gigabytes of RNA sequences in many different conditions and has highlighted an unexpected number of small RNAs (sRNAs) in bacteria. Ongoing exploitation of these data enables numerous applications for investigating bacterial transacting sRNA-mediated regulation networks. Focusing on sRNAs that regulate mRNA translation in trans, recent works have noted several sRNA-based regulatory pathways that are essential for key cellular processes. Although the number of known bacterial sRNAs is increasing, the experimental validation of their interactions with mRNA targets remains challenging and involves expensive and time-consuming experimental strategies. Hence, bioinformatics is crucial for selecting and prioritizing candidates before designing any experimental work. However, current software for target prediction produces a prohibitive number of candidates because of the lack of biological knowledge regarding the rules governing sRNA-mRNA interactions. Therefore, there is a real need to develop new approaches to help biologists focus on the most promising predicted sRNA-mRNA interactions. In this perspective, this review aims at presenting the advantages of mixing bioinformatics and visualization approaches for analyzing predicted sRNA-mediated regulatory bacterial networks. © The Author 2014. Published by Oxford University Press.

The role of steroid hormone supplementation in non-assisted reproductive technology treatments for unexplained infertility.

PubMed

Quaas, Alexander M; Hansen, Karl R

2016-12-01

Fertility treatment strategies are evolving, with a more rapid transition to assisted reproductive technology (ART) treatments after unsuccessful non-ART treatments. This trend increases the potential importance of adjuvant treatments in non-ART cycles, such as steroid hormone supplementation. It has been established that success rates of ART treatments are increased with the use of luteal support with progesterone. In the setting of non-ART cycles, however, the evidence is less clear, and clinical practices vary widely between providers and clinics. In this review, we aimed to provide an overview of the current evidence for the use of steroid hormone supplementation, including progesterone for luteal support, estrogens, androgens, and mineralocorticoids, in the setting of non-ART treatments for ovulatory women. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Art for the Brain's Sake.

ERIC Educational Resources Information Center

Sylwester, Robert

1998-01-01

From fine-tuning muscular systems to integrating emotion and logic, the arts have important biological value. Motion and emotion are central to the arts and life itself. It is counterproductive to promote high performance standards while displacing skill development with computer technologies and reducing arts programs that move students from…

International Committee for Monitoring Assisted Reproductive Technology: world report on assisted reproductive technology, 2005.

PubMed

Zegers-Hochschild, Fernando; Mansour, Ragaa; Ishihara, Osamu; Adamson, G David; de Mouzon, Jacques; Nygren, Karl G; Sullivan, Elizabeth A

2014-02-01

To analyze information on assisted reproductive technology (ART) performed worldwide and trends in outcomes over successive years. Cross-sectional survey on access, effectiveness, and safety of ART procedures performed in 53 countries during 2005. A total of 2,973 clinics from national and regional ART registries. Infertile women and men undergoing ART globally. Collection and analysis of international ART data. Number of cycles performed by country and region, including pregnancies, single and multiple birth rates, and perinatal mortality. Overall, 1,052,363 ART procedures resulted in an estimated 237,315 babies born. The availability of ART varied by country from 15 to 3,982 cycles per million of population. Of all initiated fresh cycles, 62.9% were intracytoplasmic sperm injection. The overall delivery rate per fresh aspiration was 19.6% and for frozen embryo transfer 17.4%, with a cumulative delivery rate of 23.9%. With wide regional variations, single embryo transfer represented 17.5% of cycles, and the proportion of deliveries with twins and triplets from fresh transfers was 23.6% and 1.5%, respectively. Systematic collection and dissemination of international ART data allows patients, health professionals, and policy makers to examine and compare the impact of reproductive strategies or lack of them as markers of reproductive health. Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Children's Aesthetic Understanding of Photographic Art and the Quality of Art-Related Parent-Child Interactions

ERIC Educational Resources Information Center

Szechter, Lisa E.; Liben, Lynn S.

2007-01-01

This research was designed to examine the quality of children's aesthetic understanding of photographs, observe social interactions between parents and children in this aesthetic domain, and study whether qualitatively different dyadic interactions were associated with children's own aesthetic understanding. Parents and children (7-13 years; 40…

The Imagination Machines. An Explanation of the Role of Computer Technology in Arts Education and the Impact of the Arts on New Electronic Learning Tools. [Videotape.

ERIC Educational Resources Information Center

1991

Narrated by actor Kadeem Hardison, this documentary videotape presents arguments and examples for using Computer Assisted Instruction (CAI) in today's classroom. Experts in education examine how individuals currently use technology and suggest how people can use technology better in the future to augment and improve education. Many programs are…

The impact of stress and psychosocial interventions on assisted reproductive technology outcome.

PubMed

Morreale, Mary; Balon, Richard; Tancer, Manuel; Diamond, Michael

2011-01-01

In natural cycles of attempted conception, stress has been shown to predict lower conception rates. The objective of this article is to determine whether stress affects the outcome of assisted reproductive technology (ART) as well. In addition, this article analyzes the effect that psychosocial interventions targeting the reduction of stress have on ART outcomes. This review examined available PubMed articles published in the past 15 years, and 28 articles were included. Looking specifically at numbers of women studied, stress appears to negatively affect ART outcome; interventions targeting stress reduction appear beneficial. Because stress appears to negatively affect ART outcome, and psychosocial interventions do not have detrimental effects, screening for stress should occur and some type of intervention considered during the ART process.

Demonstration of LED Retrofit Lamps at the Smithsonian American Art Museum, Washington, DC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, Naomi J.; Rosenfeld, Scott M.

This report documents observations and results obtained from a lighting demonstration project conducted under the U.S. Department of Energy GATEWAY Solid-State Lighting (SSL) Technology Demonstration Program at the Smithsonain American Art Museum in Washington, DC. LED Lamp samples were tested in the museum workshop, temporarily installed in a gallery for feedback, and ultimately replaced all traditional incandescent lamps in one gallery of modernist art at the American Art Museum and partially replacing lamps in two galleries at the Musesum's Renwick Gallery. This report describes the selection and testing process, technology challenges, perceptions, economics, energy use, and mixed results of usignmore » LED replacement lamps in art galleries housing national treasures.« less

[Access to Assisted Reproductive Technologies, surrogacy, same sex couple parenting].

PubMed

Belaisch Allart, J

2012-08-01

In France, access to Assisted Reproductive Technologies (ART) is strictly controlled. ART is only authorized for medical infertility. The revision of the law of bioethics has not modified access to ART. It is still forbidden to take charge of lesbian couples or gay-male couples, surrogacy is prohibited. The only change is that unmarried couples have no more to prove they live together since 2 years. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

A Site to Behold: Creating Curricula about Local Urban Environmental Art.

ERIC Educational Resources Information Center

Thurber, Frances E.

1997-01-01

Describes "Site Omaha" an interactive public arts project designed to explore alternative art venues in the urban environment and to create a common link between artists and other community members. "Site Omaha" initiated innovative community arts projects. Provides a brief overview of urban environmental art. (MJP)

The future of holographic technologies and their use by artists

NASA Astrophysics Data System (ADS)

Oliveira, S.; Richardson, M.

2013-02-01

The use of holographic technologies in the past has faced resistance in the artistic field. The most conservative artists and critiques saw the term "holographic" more as a technical subject than an artistic one. Nevertheless, to explore new forms to create art has been a constant challenge for any artist, whatever their field. At the end of the 20-century the concept that art can explore any field or subject, create a vision that is somehow technological, is part of the evolving artistic world. In the last two decades, in the search for new terminologies, scientists and artists have used the expression "Holographic" as a synonym of evolution, but with different meanings. Artists are using it as a new form of art call "Holo Art"; scientists see it as a "new" science technique where light takes an important part in the process, and can be used in various aspects of daily life, such as, security and medicine. This paper will explore artists who take the challenge of combining their art with new technologies and how they are viewed in a world where the question of 'what is and what isn't art' is very debatable. Other questions that will be explored are 'How can these techniques be useful to artists?' and 'How do artists challenge themselves to analyse the pros and cons of the results that can be obtained?'

Smart fabrics and interactive textile enabling wearable personal applications: R&D state of the art and future challenges.

PubMed

Lymberis, A; Paradiso, R

2008-01-01

Smart fabrics and interactive textiles (SFIT) are fibrous structures that are capable of sensing, actuating, generating/storing power and/or communicating. Research and development towards wearable textile-based personal systems allowing e.g. health monitoring, protection & safety, and healthy lifestyle gained strong interest during the last 10 years. Under the Information and Communication Programme of the European Commission, a cluster of R&D projects dealing with smart fabrics and interactive textile wearable systems regroup activities along two different and complementary approaches i.e. 'application pull' and 'technology push'. This includes projects aiming at personal health management through integration, validation, and use of smart clothing and other networked mobile devices as well as projects targeting the full integration of sensors/actuators, energy sources, processing and communication within the clothes to enable personal applications such as protection/safety, emergency and healthcare. The integration part of the technologies into a real SFIT product is at present stage on the threshold of prototyping and testing. Several issues, technical as well user-centred, societal and business, remain to be solved. The paper presents on going major R&D activities, identifies gaps and discuss key challenges for the future.

Medical mistrust as a key mediator in the association between perceived discrimination and adherence to antiretroviral therapy among HIV-positive Latino men.

PubMed

Galvan, Frank H; Bogart, Laura M; Klein, David J; Wagner, Glenn J; Chen, Ying-Tung

2017-10-01

Discrimination has been found to have deleterious effects on physical health. The goal of the present study was to examine the association between perceived discrimination and adherence to antiretroviral therapy (ART) among HIV-positive Latino men and the extent to which medical mistrust serves as a mediator of that association. A series of linear and logistic regression models was used to test for mediation for three types of perceived discrimination (related to being Latino, being perceived as gay and being HIV-positive). Medical mistrust was found to be significantly associated with perceived discrimination based on Latino ethnicity and HIV serostatus. Medical mistrust was found to mediate the associations between two types of perceived discrimination (related to being Latino and being HIV-positive) and ART adherence. Given these findings, interventions should be developed that increase the skills of HIV-positive Latino men to address both perceived discrimination and medical mistrust.

Morals or markets? Regulating assisted reproductive technologies as morality or economic policies in the states.

PubMed

Heidt-Forsythe, Erin

2017-01-01

The availability of assisted reproductive technologies (ARTs) in the medical marketplace complicates our understanding of reproductive public policy in the United States. Political debates over ARTs often are based on fundamental moral principles of life, reproduction, and kinship, similar to other reproductive policies in the United States. However, ARTs are an important moneymaking private enterprise for the U.S. biotechnology industry. This project investigates how the U.S. states regulate these unique and challenging technologies as either moral policies or economic policies. This study employs ordinary least squares (OLS) regression to estimate the significance of morality and economic policy variables on ART policies at the state level, noting associations between state-level political, economic, and gender variables on restrictive and permissive state-level ART policies. Economic variables (reflecting the biotechnology industry) and advocacy for access to ART on behalf of infertility patients increase the chances of states passing policies that enable consumer use of ARTs. Additionally, individual ART policies are distinct from one another in the ways that morality variables increase the chances of ART regulations. Surprisingly, the role of religious adherence among state residents varied in positive and negative relationships with individual policy passage. In general, these results support the hypothesis that ART laws are associated with economic as well as moral concerns of the states-ARTs lie at the intersection of issues of life and reproduction and of scientific innovation and health. What is most striking about these results is that they do not follow patterns seen in the legislation of abortion, contraception, and sexuality in general-those reproductive policies that are considered "morality policy." Similarly, economic variables are not consistently significant in the expected direction.

Rap and Technology Teach the Art of Argument

ERIC Educational Resources Information Center

Fink, Rosalie

2017-01-01

How can teachers integrate rap and technology strategies to teach students with learning disabilities the art of persuasive argument writing? This teacher research study presents creative new approaches for teaching argument writing. Strategies used in the study helped college freshmen with learning disabilities (LD) succeed in developing…

Science & Technology: A New Alliance.

ERIC Educational Resources Information Center

Lux, Donald G.

Understandings and cooperation must be improved between researchers in pure science and applied science, and in this case, industrial arts. Technology has crept into science but is seldom an organized part of the science curriculum. Few science teachers have contact with engineers or technologists, while industrial arts teachers typically have…

CLEANING EXCAVATED SOIL USING EXTRACTION AGENTS: A STATE-OF-THE-ART REVIEW

EPA Science Inventory

This report presents a state-of-the-art review of soil washing technologies and their applicability to Superfund sites in the United States. The review includes Superfund site soil and contamination characteristics; as well as soil cleaning technologies, their principles of opera...

Socio-Cultural Theories of Cognitive Development: Implications for Teaching Theory in the Visual Arts.

ERIC Educational Resources Information Center

Fielding, Rob

1989-01-01

Explicates the socio-cultural developmental theories of Vygotsky and Feuerstein which advocate teacher mediated learning in order to stimulate and accelerate development. Implications for art education include the need for the teacher to become involved in the enculturation of the child into the thinking processes and conceptual organization of…

An integrated systems engineering approach to aircraft design

NASA Astrophysics Data System (ADS)

Price, M.; Raghunathan, S.; Curran, R.

2006-06-01

The challenge in Aerospace Engineering, in the next two decades as set by Vision 2020, is to meet the targets of reduction of nitric oxide emission by 80%, carbon monoxide and carbon dioxide both by 50%, reduce noise by 50% and of course with reduced cost and improved safety. All this must be achieved with expected increase in capacity and demand. Such a challenge has to be in a background where the understanding of physics of flight has changed very little over the years and where industrial growth is driven primarily by cost rather than new technology. The way forward to meet the challenges is to introduce innovative technologies and develop an integrated, effective and efficient process for the life cycle design of aircraft, known as systems engineering (SE). SE is a holistic approach to a product that comprises several components. Customer specifications, conceptual design, risk analysis, functional analysis and architecture, physical architecture, design analysis and synthesis, and trade studies and optimisation, manufacturing, testing validation and verification, delivery, life cycle cost and management. Further, it involves interaction between traditional disciplines such as Aerodynamics, Structures and Flight Mechanics with people- and process-oriented disciplines such as Management, Manufacturing, and Technology Transfer. SE has become the state-of-the-art methodology for organising and managing aerospace production. However, like many well founded methodologies, it is more difficult to embody the core principles into formalised models and tools. The key contribution of the paper will be to review this formalisation and to present the very latest knowledge and technology that facilitates SE theory. Typically, research into SE provides a deeper understanding of the core principles and interactions, and helps one to appreciate the required technical architecture for fully exploiting it as a process, rather than a series of events. There are major issues as regards to systems approach to aircraft design and these include lack of basic scientific/practical models and tools for interfacing and integrating the components of SE and within a given component, for example, life cycle cost, basic models for linking the key drivers. The paper will review the current state of art in SE approach to aircraft design and identify some of the major challenges, the current state of the art and visions for the future. The review moves from an initial basis in traditional engineering design processes to consideration of costs and manufacturing in this integrated environment. Issues related to the implementation of integration in design at the detailed physics level are discussed in the case studies.

Practical Arts. Arkansas Public School Course Content Guide.

ERIC Educational Resources Information Center

Arkansas State Dept. of Education, Little Rock.

This guide outlines the basic, developmental, and extension skills that should be covered in practical arts courses (for grades 7 and 8) presented within the framework of agricultural, business, home economics, and industrial arts/technology education programs. The first section lists practical arts skills related to the following areas of…

Art Libraries Section. Special Libraries Division. Papers.

ERIC Educational Resources Information Center

International Federation of Library Associations, The Hague (Netherlands).

Papers on art libraries and information services for the arts, which were presented at the 1983 International Federation of Library Associations (IFLA) conference, include: (1) "'I See All': Information Technology and the Universal Availability of Images" by Philip Pacey (United Kingdom); (2) "Online Databases in the Fine Arts"…

Learning about Computers through Art History and Art Practice.

ERIC Educational Resources Information Center

Lichtman, Loy

1996-01-01

Describes a Victoria University (Australia) program that combines art history, computer graphics, and studio practice. Discusses the social applications of technology, the creation and manipulation of computer imagery, and the ways that these impact traditional concepts of art. The program has proven particularly successful with female students.…

X-34 Poster Art

NASA Technical Reports Server (NTRS)

2004-01-01

Pictured is NASA's poster art for the X-34 technology Demonstrator. The X-34 was part of NASA's Pathfinder Program which demonstrated advanced space transportation technologies through the use of flight experiments and experimental vehicles. These technology demonstrators and flight experiments would support the Agency's goal of dramatically reducing the cost of access to space and would define the future of space transportation pushing technology into a new era of space development and exploration at the dawn of the new century. The X-34 program was cancelled in 2001.

Intersegmental Eye-Head-Body Interactions during Complex Whole Body Movements

PubMed Central

von Laßberg, Christoph; Beykirch, Karl A.; Mohler, Betty J.; Bülthoff, Heinrich H.

2014-01-01

Using state-of-the-art technology, interactions of eye, head and intersegmental body movements were analyzed for the first time during multiple twisting somersaults of high-level gymnasts. With this aim, we used a unique combination of a 16-channel infrared kinemetric system; a three-dimensional video kinemetric system; wireless electromyography; and a specialized wireless sport-video-oculography system, which was able to capture and calculate precise oculomotor data under conditions of rapid multiaxial acceleration. All data were synchronized and integrated in a multimodal software tool for three-dimensional analysis. During specific phases of the recorded movements, a previously unknown eye-head-body interaction was observed. The phenomenon was marked by a prolonged and complete suppression of gaze-stabilizing eye movements, in favor of a tight coupling with the head, spine and joint movements of the gymnasts. Potential reasons for these observations are discussed with regard to earlier findings and integrated within a functional model. PMID:24763143

Socio-economic marginalization and plasma HIV-1 RNA non-detectability among individuals who use illicit drugs in a Canadian setting

PubMed Central

RICHARDSON, Lindsey A.; KERR, Thomas H.; DOBRER, Sabina; PUSKAS, Cathy M.; GUILLEMI, Silvia A.; MONTANER, Julio S. G.; WOOD, Evan; MILLOY, M-J. S.

2015-01-01

Objective Given that people who use illicit drugs (PWUD) often engage in prohibited income generation to support their basic needs, we sought to examine the role of these activities in shaping antiretroviral therapy (ART) adherence and plasma HIV RNA-1 viral load suppression among HIV-infected PWUD. Design Longitudinal analyses among HIV-positive, ART exposed PWUD in the AIDS Care Cohort to evaluate Exposure to Survival Services prospective cohort study (2005–2013). Methods Generalized linear mixed effects and mediation analyses examined the relationship between prohibited income generation (e.g. sex work, drug dealing, theft, street-based income) and virologic suppression (plasma viral load ≤ 50 copies/mL plasma) adjusting for adherence and potential confounders. Results Among 687 HIV-infected PWUD, 391 (56.9%) individuals reported prohibited income generation activity during the study period. In multivariate analyses, prohibited income generation remained independently and negatively associated with virologic suppression (adjusted odds ratio: 0.68, 95% confidence interval: 0.52–0.88) following adjustment for hypothesized confounders, including high-intensity drug use, ART adherence and homelessness. While partially mediated by ART adherence, the relationship between prohibited income generation and virologic suppression was maintained in mediation analyses (Sobel statistic = −1.95, p=0.05). Conclusions Involvement in prohibited income generation decreases the likelihood of virologic suppression directly and indirectly through its negative association with ART adherence. These findings suggest that linkages between socio-economic marginalization, the criminalization of illicit drug use and insufficient employment opportunities may produce barriers to access and retention in care. Programmatic and policy interventions that decrease socio-economic vulnerability may therefore reduce HIV-related morbidity, mortality and onward transmission. PMID:26558546

Transforming an educational virtual reality simulation into a work of fine art.

PubMed

Panaiotis; Addison, Laura; Vergara, Víctor M; Hakamata, Takeshi; Alverson, Dale C; Saiki, Stanley M; Caudell, Thomas Preston

2008-01-01

This paper outlines user interface and interaction issues, technical considerations, and problems encountered in transforming an educational VR simulation of a reified kidney nephron into an interactive artwork appropriate for a fine arts museum.

History of Assisted Reproductive Technology and Chlamydia Trachomatis Infection in Pregnancy

PubMed Central

Kato, Masahiko; Suzuki, Shunji

2016-01-01

Background and Methods To identify whether or not a history of assisted reproductive technology (ART) is associated with the low incidence of Chlamydia trachomatis (CT) infection in pregnant women, we reviewed the obstetric records of the Japanese women aged 35 - 42 years. Results The prevalence of CT in the pregnancies without ART was 1.1% (28/2,632) using nucleic acid amplification tests, while it was zero in the pregnancies conceived by ART (0/364, P = 0.049 by the X2 test). Conclusions A history of ART seemed to be a negative risk factor for CT infection in pregnant women. PMID:26858799

Bioethics for clinicians: 26. Assisted reproductive technologies

PubMed Central

Shanner, Laura; Nisker, Jeffrey

2001-01-01

ASSISTED REPRODUCTIVE TECHNOLOGIES (ARTs) can be very helpful for certain patients, but ethical concerns have been raised about the inherent nature of specific techniques and the contexts in which many techniques are used. Physicians play important roles in supporting those who wish to become parents and in educating patients about impediments to fertilization and ways to promote conception. We discuss various ethical issues surrounding ARTs, including family relationships, informed choice, gender issues, embryo status and the commercialization of reproduction, as well as legal and policy issues. We examine the empirical evidence of the effectiveness of ARTs and suggest ways to approach ARTs in practice. PMID:11402801

An Interview with Marcia McCaffrey about the Core Arts Standards: Implications for Arts Teacher Evaluation

ERIC Educational Resources Information Center

Shaw, Ryan D.

2014-01-01

This article reports on an interview with Marcia McCaffrey, the state arts consultant for the New Hampshire Department of Education and current president of the State Education Agency Directors of Arts Education (SEADAE). The discussion revolved around how the new arts standards may interact with evolving structures of arts teacher evaluation…

A "Neogeographical Education"? The Geospatial Web, GIS and Digital Art in Adult Education

ERIC Educational Resources Information Center

Papadimitriou, Fivos

2010-01-01

Neogeography provides a link between the science of geography and digital art. The carriers of this link are geospatial technologies (global navigational satellite systems such as the global positioning system, Geographical Information System [GIS] and satellite imagery) along with ubiquitous information and communication technologies (such as…

Desktop Simulation: Towards a New Strategy for Arts Technology Education

ERIC Educational Resources Information Center

Eidsheim, Nina Sun

2009-01-01

For arts departments in many institutions, technology education entails prohibitive equipment costs, maintenance requirements and administrative demands. There are also inherent pedagogical challenges: for example, recording studio classes where, due to space and time constraints, only a few students in what might be a large class can properly…

Student Evaluation of Audience Response Technology in Large Lecture Classes

ERIC Educational Resources Information Center

MacGeorge, Erina L.; Homan, Scott R.; Dunning, John B., Jr.; Elmore, David; Bodie, Graham D.; Evans, Ed; Khichadia, Sangeetha; Lichti, Steven M.; Feng, Bo; Geddes, Brian

2008-01-01

In the past few years, audience response technology (ART) has been widely adopted on college campuses, and is especially popular among instructors of large lecture classes. Claims regarding ART's benefits to students have received only limited empirical evaluation, and prior studies exhibit methodological limitations. The current study provides a…

Whole-Language Strategies for Integrating Technology into Language Arts.

ERIC Educational Resources Information Center

Stuhlmann, Janice; Taylor, Harriet

This paper presents proven strategies and benefits of integrating technology into the language-arts curriculum and instruction. Benefits include creating a risk-free learning environment; increasing student empowerment; providing the opportunity for students to practice skills in meaningful contexts; and increasing interest in reading and writing.…

When a Body Meets a Body: An Exploration of the Negative Impact of Social Interactions on Museum Experiences of Art

ERIC Educational Resources Information Center

Pelowski, Matthew; Liu, Tao; Palacios, Victor; Akiba, Fuminori

2014-01-01

We consider the phenomenon of social interactions within the art museum, arguing that even the bare possibility of meeting others or intruding into their gaze can have a profoundly detrimental effect on art experience. This is done by tracing a finding from our previous studies in which we considered three museum galleries--each with the same…

Risk disparities in the globalisation of assisted reproductive technology: the case of Asia.

PubMed

Ha, Jung-Ok

2013-01-01

This paper analyses the disparities in risks associated with biomedical technology focusing on the results of assisted reproductive technology (ART). ART among biomedical technologies transferred to Asia is a representative case that reveals in its clinical use and related scientific research the global politics of technology. This study notes the global politics at work in the recognition of and reaction to such risks. While many Asian countries aggressively pursue technological development, weak legislative and administrative regulations have created various problems and controversial cases. This study asserts that risks associated with technology are characterised as social facts not natural ones or mere 'side effects', since technological development and risk are closely intertwined.

The Integration Method of Ceramic Arts in the Product Design

NASA Astrophysics Data System (ADS)

Shuxin, Wang

2018-03-01

As one of the four ancient civilization countries, the firing technology of ceramic invented by China has made a great contribution to the progress and development of human society. In modern life, even the development of technology still needs the ceramics, there are large number of artists who take the ceramics as carrier active in the field of contemporary art. The ceramics can be seen everywhere in our daily life, this paper mainly discusses the integration means of ceramic art in the product design.

Art as Relational Encounter: An Ostensive Communication Theory of Art Therapy

ERIC Educational Resources Information Center

Springham, Neil; Huet, Val

2018-01-01

Biopsychosocial theory is strengthening psychotherapy by focusing on interactions that engage the attachment system. Art therapy has the potential to align coherently with current theory provided it addresses the value of art in engaging with the attachment system. This article describes an interpersonal theory of art therapy based on a model of…

Economic Impact of the Arts: A Sourcebook.

ERIC Educational Resources Information Center

National Conference of State Legislatures, Washington, DC.

This book represents a collection of 7 works by authors arguing for the support of public spending on the arts: (1) "Introduction: The Value of Economic Reasoning and the Arts" (Harry Hillman-Chartrand), examines the changing social perception of the arts over time, and describes the interaction among the sectors of the arts; (2)…

Plant-pathogen interactions: what microarray tells about it?

PubMed

Lodha, T D; Basak, J

2012-01-01

Plant defense responses are mediated by elementary regulatory proteins that affect expression of thousands of genes. Over the last decade, microarray technology has played a key role in deciphering the underlying networks of gene regulation in plants that lead to a wide variety of defence responses. Microarray is an important tool to quantify and profile the expression of thousands of genes simultaneously, with two main aims: (1) gene discovery and (2) global expression profiling. Several microarray technologies are currently in use; most include a glass slide platform with spotted cDNA or oligonucleotides. Till date, microarray technology has been used in the identification of regulatory genes, end-point defence genes, to understand the signal transduction processes underlying disease resistance and its intimate links to other physiological pathways. Microarray technology can be used for in-depth, simultaneous profiling of host/pathogen genes as the disease progresses from infection to resistance/susceptibility at different developmental stages of the host, which can be done in different environments, for clearer understanding of the processes involved. A thorough knowledge of plant disease resistance using successful combination of microarray and other high throughput techniques, as well as biochemical, genetic, and cell biological experiments is needed for practical application to secure and stabilize yield of many crop plants. This review starts with a brief introduction to microarray technology, followed by the basics of plant-pathogen interaction, the use of DNA microarrays over the last decade to unravel the mysteries of plant-pathogen interaction, and ends with the future prospects of this technology.

Automated identification of protein-ligand interaction features using Inductive Logic Programming: a hexose binding case study

PubMed Central

2012-01-01

Background There is a need for automated methods to learn general features of the interactions of a ligand class with its diverse set of protein receptors. An appropriate machine learning approach is Inductive Logic Programming (ILP), which automatically generates comprehensible rules in addition to prediction. The development of ILP systems which can learn rules of the complexity required for studies on protein structure remains a challenge. In this work we use a new ILP system, ProGolem, and demonstrate its performance on learning features of hexose-protein interactions. Results The rules induced by ProGolem detect interactions mediated by aromatics and by planar-polar residues, in addition to less common features such as the aromatic sandwich. The rules also reveal a previously unreported dependency for residues cys and leu. They also specify interactions involving aromatic and hydrogen bonding residues. This paper shows that Inductive Logic Programming implemented in ProGolem can derive rules giving structural features of protein/ligand interactions. Several of these rules are consistent with descriptions in the literature. Conclusions In addition to confirming literature results, ProGolem’s model has a 10-fold cross-validated predictive accuracy that is superior, at the 95% confidence level, to another ILP system previously used to study protein/hexose interactions and is comparable with state-of-the-art statistical learners. PMID:22783946

LPA3-mediated lysophosphatidic acid signalling in implantation and embryo spacing

PubMed Central

Ye, Xiaoqin; Hama, Kotaro; Contos, James J.A.; Anliker, Brigitte; Inoue, Aska; Skinner, Michael K.; Suzuki, Hiroshi; Amano, Tomokazu; Kennedy, Grace; Arai, Hiroyuki; Aoki, Junken; Chun, Jerold

2005-01-01

Every successful pregnancy requires proper embryo implantation. Low implantation rate is a major problem during infertility treatments using assisted reproductive technologies (ART) 1. Here we report a new molecular influence on implantation through the lysophosphatidic acid (LPA) receptor LPA3 2–4. Targeted deletion of LPA3 in mice resulted in significantly reduced litter size, which could be attributed to delayed implantation and altered embryo spacing. These two events led to delayed embryonic development, hypertrophic placentas shared by multiple embryos, and embryonic death. An enzyme demonstrated to influence implantation, cyclooxygenase-2 (COX-2) 5, was down-regulated in LPA3-deficient uteri during preimplantation. Down regulation of COX-2 led to reduced levels of prostaglandins that are critical for implantation 1. Exogenous administration of the prostaglandins PGE2 and cPGI into LPA3-deficient females rescued delayed implantation but did not rescue defects in embryo spacing. These data identify LPA3 receptor-mediated signalling as a new influence on implantation and further indicate linkage between LPA signalling and prostaglandin biosynthesis. PMID:15875025

Long-term follow-up of children conceived through assisted reproductive technology.

PubMed

Lu, Yue-hong; Wang, Ning; Jin, Fan

2013-05-01

Children conceived via assisted reproductive technologies (ART) are nowadays a substantial proportion of the population. It is important to follow up these children and evaluate whether they have elevated health risks compared to naturally conceived (NC) children. In recent years there has been a lot of work in this field. This review will summarize what is known about the health of ART-conceived children, encompassing neonatal outcomes, birth defects, growth and gonadal developments, physical health, neurological and neurodevelopmental outcomes, psychosocial developments, risk for cancer, and epigenetic abnormalities. Most of the children conceived after ART are normal. However, there is increasing evidence that ART-conceived children are at higher risk of poor perinatal outcome, birth defects, and epigenetic disorders, and the mechanism(s) leading to these changes have not been elucidated. Continuous follow-up of children after ART is of great importance as they progress through adolescence into adulthood, and new ART techniques are constantly being introduced.

Increased Length of Awareness of Assisted Reproductive Technologies Fosters Positive Attitudes and Acceptance among Women

PubMed Central

Fortin, Chelsea; Abele, Susanne

2016-01-01

Background The field of infertility medicine has witnessed a surge of scientific developments in recent years, but research on public attitudes towards infertility treatments has remained minimal. This study examined the social and demographic factors that affect women’s attitudes towards assisted reproductive technology (ART) in general, as well as their opinions of specific issues related to ART. Materials and Methods This cross-sectional study was conducted from March 2011 to April 2011 by means of an online survey administered to a sample of 287 women. Results Women with a longer length of awareness of ART had significantly greater attitudinal favorability towards ART. Political affiliation was also significantly related to general attitudes, as well as several specific aspects of ART issues. Conclusion The results of this study suggest that several factors influence attitudes that women hold in regards to ART. Identifying some of these factors serves as a crucial starting point for devising strategies to increase public acceptance of ART. PMID:27110326

New advances in probing cell–extracellular matrix interactions

PubMed Central

2017-01-01

The extracellular matrix (ECM) provides structural and biochemical support to cells within tissues. An emerging body of evidence has established that the ECM plays a key role in cell mechanotransduction – the study of coupling between mechanical inputs and cellular phenotype – through either mediating transmission of forces to the cells, or presenting mechanical cues that guide cellular behaviors. Recent progress in cell mechanotransduction research has been facilitated by advances of experimental tools, particularly microtechnologies, engineered biomaterials, and imaging and analytical methods. Microtechnologies have enabled the design and fabrication of controlled physical microenvironments for the study and measurement of cell–ECM interactions. Advances in engineered biomaterials have allowed researchers to develop synthetic ECMs that mimic tissue microenvironments and investigate the impact of altered physicochemical properties on various cellular processes. Finally, advanced imaging and spectroscopy techniques have facilitated the visualization of the complex interaction between cells and ECM in vitro and in living tissues. This review will highlight the application of recent innovations in these areas to probing cell–ECM interactions. We believe cross-disciplinary approaches, combining aspects of the different technologies reviewed here, will inspire innovative ideas to further elucidate the secrets of ECM-mediated cell control. PMID:28352896

Use of speech generating devices can improve perception of qualifications for skilled, verbal, and interactive jobs.

PubMed

Stern, Steven E; Chobany, Chelsea M; Beam, Alexander A; Hoover, Brittany N; Hull, Thomas T; Linsenbigler, Melissa; Makdad-Light, Courtney; Rubright, Courtney N

2017-01-01

We have previously demonstrated that when speech generating devices (SGD) are used as assistive technologies, they are preferred over the users' natural voices. We sought to examine whether using SGDs would affect listener's perceptions of hirability of people with complex communication needs. In a series of three experiments, participants rated videotaped actors, one using SGD and the other using their natural, mildly dysarthric voice, on (a) a measurement of perceptions of speaker credibility, strength, and informedness and (b) measurements of hirability for jobs coded in terms of skill, verbal ability, and interactivity. Experiment 1 examined hirability for jobs varying in terms of skill and verbal ability. Experiment 2 was a replication that examined hirability for jobs varying in terms of interactivity. Experiment 3 examined jobs in terms of skill and specific mode of interaction (face-to-face, telephone, computer-mediated). Actors were rated more favorably when using SGD than their own voices. Actors using SGD were also rated more favorably for highly skilled and highly verbal jobs. This preference for SGDs over mildly dysarthric voice was also found for jobs entailing computer-mediated-communication, particularly skillful jobs.