NMDA and D1 receptors are involved in one-trial tolerance to the anxiolytic-like effects of diazepam in the elevated plus maze test in rats.

PubMed

Zhou, Heng; Yu, Cheng-Long; Wang, Li-Ping; Yang, Yue-Xiong; Mao, Rong-Rong; Zhou, Qi-Xin; Xu, Lin

2015-08-01

The elevated plus maze (EPM) test is used to examine anxiety-like behaviors in rodents. One interesting phenomenon in the EPM test is one-trial tolerance (OTT), which refers to the reduction in the anxiolytic-like effects of benzodiazepines when rodents are re-exposed to the EPM. However, the underlying mechanism of OTT is still unclear. In this study, we reported that OTT occurred when re-exposure to the EPM (trial 2) only depended on the prior experience of the EPM (trial 1) rather than diazepam treatment. This process was memory-dependent, as it was prevented by the N-methyl-D-aspartate (NMDA) receptors antagonist MK-801 1.5h before trial 2. In addition, OTT was maintained for at least one week but was partially abolished after an interval of 28 days. Furthermore, the administration of the D1-like receptors agonist SKF38393 to the bilateral dorsal hippocampus largely prevented OTT, as demonstrated by the ability of the diazepam treatment to produce significant anxiolytic-like effects in trial 2 after a one-day interval. These findings suggest that OTT to the EPM test may occur via the activation of NMDA receptors and the inactivation of D1-like receptors in certain brain regions, including the hippocampus. Copyright © 2015 Elsevier Inc. All rights reserved.

A New Forced Oscillation Capability for the Transonic Dynamics Tunnel

NASA Technical Reports Server (NTRS)

Piatak, David J.; Cleckner, Craig S.

2002-01-01

A new forced oscillation system has been installed and tested at NASA Langley Research Center's Transonic Dynamics Tunnel (TDT). The system is known as the Oscillating Turntable (OTT) and has been designed for the purpose of oscillating, large semispan models in pitch at frequencies up to 40 Hz to acquire high-quality unsteady pressure and loads data. Precisely controlled motions of a wind-tunnel model on the OTT can yield unsteady aerodynamic phenomena associated with flutter, limit cycle oscillations, shock dynamics, and non-linear aerodynamic effects on many vehicle configurations. This paper will discuss general design and components of the OTT and will present test data from performance testing and from research tests on two rigid semispan wind-tunnel models. The research tests were designed to challenge the OTT over a wide range of operating conditions while acquiring unsteady pressure data on a small rectangular supercritical wing and a large supersonic transport wing. These results will be presented to illustrate the performance capabilities, consistency of oscillations, and usefulness of the OTT as a research tool.

Use of Minute-by-Minute Cardiovascular Measurements During Tilt Tests to Strengthen Inference on the Effect of Long-Duration Space Flight on Orthostatic Hypotension

NASA Technical Reports Server (NTRS)

Feiveson, Alan H.; Lee, Stuart M. C.; Stenger, Michael B.; Stein, Sydney P.; Platts, Steven H.

2011-01-01

Typical methodology for evaluating the effects of spaceflight on orthostatic hypotension (OH) has been survival analysis of tolerance times from 80 head-up tilt tests. However when scheduled test durations are short, there may not be enough failures to allow survival analysis to adequately estimate and compare the effects of flight phase (e.g. pre-flight, number of days post-flight), flight duration, and their interaction, as well as interactions with effects of interventions or countermeasures. The problem is exacerbated in the presence of a repeated measures design, in which subjects participate in tilt tests during various flight phases. Here we show how it is possible to dramatically improve the efficiency of statistical inference in this setting by making use of the additional information contained in minute-by-minute observations of cardiovascular parameters thought to be reflective of progression towards presyncope during tilt testing. Methods: We retrospectively examined operational tilt test (OTT; 10 -min 80 head-up tilt) data from 20 International Space Station (ISS) and 66 Shuttle astronauts 10 d before launch (L-10), on landing day (R+0) and during recovery (R+1, R+3, R+6-10) depending on the level of participation. Data from 5 ISS astronauts tested on R+0 or R+1 who used non-standard countermeasures were excluded. In addition to OTT survival time, 8 cardiovascular parameters (CP: heart rate, systolic, diastolic, and mean arterial blood pressure, pulse pressure, stroke volume, cardiac output, and total peripheral resistance) that might be predictive of progression towards presyncope were measured every minute of each OTT. Statistical analysis was predicated on a two ]stage model of causation. In the first stage, flight duration and time from landing affect the astronauts' degree of OH, which is manifested in the time trends and variation of the above CPs during OTTs. In the second stage, the behavior of these parameters directly affects OTT survival time. Actual analysis proceeded in the opposite direction. First we identified those CPs or linear combinations that best predicted OTT survival regardless of what spaceflight conditions led to OTT completion or presyncope. From these, we calculated a summary statistic (one per OTT) that best predicted survival. We then used mixed ]model regression analysis to relate changes in the summary statistic to flight phase and duration. Inference on the effects of phase, duration, and their interaction on OH follows directly from this second analysis. Results: A linear combination (W) of diastolic blood pressure (DBP) and stroke volume (SV) was found to be the best predictor of OTT survival using the complete data set of minute-by-minute observations of CPs for each OTT. Furthermore, the log-transformed standard deviation of W (Z = log SW) was found to be a strong predictor of survival in the reduced data set consisting of one observation per OTT. In other words, this measure of variability of W during an OTT was the best indicator of whether or not the subject could complete the 10-min test, with higher variability (i.e. higher values of Z) being associated with greater probability of failure. In the mixed-model regression analysis where Z was now treated as a outcome with flight phase and duration groups (ISS and STS) as predictors, we found that there was a significantly more variability in W (higher values of Z) for both groups at R+0, but with no evidence of an interaction until R+3, when the ISS group still had inflated variability, but not the STS group. Conclusions: Variability of the cardiovascular index W recovers more slowly after long-compared to short-duration spaceflight. Since high variability of W has also been shown to be predictive of OTT failure, a primary manifestation of OH, a logical conclusion is that recovery from OH also is slower after long-duration compared to short-duration spaceflights.

Correlation of the oldest Toba Tuff to sediments in the central Indian Ocean Basin

NASA Astrophysics Data System (ADS)

Pattan, J. N.; Shyam Prasad, M.; Babu, E. V. S. S. K.

2010-08-01

We have identified an ash layer in association with Australasian microtektites of ˜0.77 Ma old in two sediment cores which are ˜450 km apart in the central Indian Ocean Basin (CIOB). Morphology and chemical composition of glass shards and associated microtektites have been used to trace their provenance. In ODP site 758 from Ninetyeast Ridge, ash layer-D (13 cm thick, 0.73-0.75 Ma) and layer-E (5 cm thick, 0.77-0.78 Ma) were previously correlated to the oldest Toba Tuff (OTT) eruptions of the Toba caldera, Sumatra. In this investigation, we found tephra ˜3100 km to the southwest of Toba caldera that is chemically identical to layer D of ODP site 758 and ash in the South China Sea correlated to the OTT. Layer E is not present in the CIOB or other ocean basins. The occurrence of tephra correlating to layer D suggests a widespread distribution of OTT tephra (˜3.6 × 107 km2), an ash volume of at least ˜1800 km3, a total OTT volume of 2300 km3, and classification of the OTT eruption as a super-eruption.

Remediation System Evaluation, Ott/Story/Cordova Superfund Site

EPA Pesticide Factsheets

The Ott/Story/Cordova Superfund Site occupies approximately 20 acres in Dalton Township, MuskegonCounty, Michigan. The remedies at the site address contamination stemming from a specialty organicchemical production facility operated under a series of..

Ecological validity of the five digit test and the oral trails test.

PubMed

Paiva, Gabrielle Chequer de Castro; Fialho, Mariana Braga; Costa, Danielle de Souza; Paula, Jonas Jardim de

2016-01-01

Tests evaluating the attentional-executive system are widely used in clinical practice. However, proximity of an objective cognitive test with real-world situations (ecological validity) is not frequently investigated. The present study evaluate the association between measures of the Five Digit Test (FDT) and the Oral Trails Test (OTT) with self-reported cognitive failures in everyday life as measured by the Cognitive Failures Questionnaire (CFQ). Brazilian adults from 18-to-65 years old voluntarily performed the FDT and OTT tests and reported the frequency of cognitive failures in their everyday life through the CFQ. After controlling for the age effect, the measures of controlled attentional processes were associated with cognitive failures, yet the cognitive flexibility of both FDT and OTT accounted for by the majority of variance in most aspects of the CFQ factors. The FDT and the OTT measures were predictive of real-world problems such as cognitive failures in everyday activities/situations.

Modulatory Effect of Aerobic Physical Activity on Synaptic Ultrastructure in the Old Mouse Hippocampus.

PubMed

Fattoretti, Patrizia; Malatesta, Manuela; Cisterna, Barbara; Milanese, Chiara; Zancanaro, Carlo

2018-01-01

Aerobic physical exercise (APE) leads to improved brain functions. To better understand the beneficial effect of APE on the aging brain, a morphometric study was carried out of changes in hippocampal synapses of old (>27 months) Balb/c mice undergoing treadmill training (OTT) for 4 weeks in comparison with old sedentary (OS), middle-aged sedentary (MAS) and middle-aged treadmill training (MATT) mice. The inner molecular layer of the hippocampal dentate gyrus (IMLDG) and the molecular stratum of Ammon's horn1 neurons (SMCA1) were investigated. The number of synapses per cubic micron of tissue (numeric density, Nv), overall synaptic area per cubic micron of tissue (surface density, Sv), average area of synaptic contact zones (S), and frequency (%) of perforated synapses (PS) were measured in electron micrographs of ethanol-phosphotungstic acid (E-PTA) stained tissue. Data were analyzed with analysis of variance (ANOVA). In IMLDG, an effect of age was found for Nv and Sv, but not S and %PS. Similar results were found for exercise and the interaction of age and exercise. In post hoc analysis Nv was higher (60.6% to 75.1%; p < 0.001) in MATT vs. MAS, OS and OTT. Sv was higher (32.3% to 54.6%; p < 0.001) in MATT vs. MAS, OS and OTT. In SMCA1, age affected Nv, Sv and %PS, but not S. The effect of exercise was significant for Sv only. The interaction of age and exercise was significant for Nv, Sv and %PS. In post hoc analysis Nv was lower in OS vs. MAS, MATT and OTT (-26.1% to -32.1%; p < 0.038). MAS and OTT were similar. Sv was lower in OS vs. MAS, MATT and OTT (-23.4 to -30.3%, p < 0.004). MAS and OTT were similar. PS frequency was higher in OS vs. MAS, MATT and OTT (48.3% to +96.6%, p < 0.023). APE positively modulated synaptic structural dynamics in the aging hippocampus, possibly in a region-specific way. The APE-associated reduction in PS frequency in SMCA1 of old mice suggests that an increasing complement of PS is a compensatory phenomenon to maintain synaptic efficacy. In conclusion, the modulation of synaptic plasticity by APE gives quantitative support to the concept that APE protects from neurodegeneration and improves learning and memory in aging.

High-Dose Split-Course Radiation Therapy for Anal Cancer: Outcome Analysis Regarding the Boost Strategy (CORS-03 Study)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hannoun-Levi, Jean-Michel, E-mail: jean-michel.hannoun-levi@nice.fnclcc.fr; Cercle des Oncologues Radiotherapeutes du Sud; Ortholan, Cecile

2011-07-01

Purpose: To retrospectively assess the clinical outcome in anal cancer patients treated with split-course radiation therapy and boosted through external-beam radiation therapy (EBRT) or brachytherapy (BCT). Methods and Materials: From January 2000 to December 2004, a selected group (162 patients) with invasive nonmetastatic anal squamous cell carcinoma was studied. Tumor staging reported was T1 = 31 patients (19%), T2 = 77 patients (48%), T3 = 42 patients (26%), and T4= 12 patients (7%). Lymph node status was N0-1 (86%) and N2-3 (14%). Patients underwent a first course of EBRT: mean dose 45.1 Gy (range, 39.5-50) followed by a boost: meanmore » dose 17.9 Gy (range, 8-25) using EBRT (76 patients, 47%) or BCT (86 patients, 53%). All characteristics of patients and tumors were well balanced between the BCT and EBRT groups. Results: The mean overall treatment time (OTT) was 82 days (range, 45-143) and 67 days (range, 37-128) for the EBRT and BCT groups, respectively (p < 0.001). The median follow-up was 62 months (range, 2-108). The 5-year cumulative rate of local recurrence (CRLR) was 21%. In the univariate analysis, the prognostic factors for CRLR were as follows: T stage (T1-2 = 15% vs. T3-4 = 36%, p = 0.03), boost technique (BCT = 12% vs. EBRT = 33%, p = 0.002) and OTT (OTT <80 days = 14%, OTT {>=}80 days = 34%, p = 0.005). In the multivariate analysis, BCT boost was the unique prognostic factor (hazard ratio = 0.62 (0.41-0.92). In the subgroup of patients with OTT <80 days, the 5-year CRLR was significantly increased with the BCT boost (BC = 9% vs. EBRT = 28%, p = 0.03). In the case of OTT {>=}80 days, the 5-year CRLR was not affected by the boost technique (BCT = 29% vs. EBRT = 38%, p = 0.21). Conclusion: In anal cancer, when OTT is <80 days, BCT boost is superior to EBRT boost for CRLR. These results suggest investigating the benefit of BCT boost in prospective trials.« less

The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model

PubMed Central

Mercher, Thomas; Raffel, Glen D.; Moore, Sandra A.; Cornejo, Melanie G.; Baudry-Bluteau, Dominique; Cagnard, Nicolas; Jesneck, Jonathan L.; Pikman, Yana; Cullen, Dana; Williams, Ifor R.; Akashi, Koichi; Shigematsu, Hirokazu; Bourquin, Jean-Pierre; Giovannini, Marco; Vainchenker, William; Levine, Ross L.; Lee, Benjamin H.; Bernard, Olivier A.; Gilliland, D. Gary

2009-01-01

Acute megakaryoblastic leukemia (AMKL) is a form of acute myeloid leukemia (AML) associated with a poor prognosis. The genetics and pathophysiology of AMKL are not well understood. We generated a knockin mouse model of the one twenty-two–megakaryocytic acute leukemia (OTT-MAL) fusion oncogene that results from the t(1;22)(p13;q13) translocation specifically associated with a subtype of pediatric AMKL. We report here that OTT-MAL expression deregulated transcriptional activity of the canonical Notch signaling pathway transcription factor recombination signal binding protein for immunoglobulin κ J region (RBPJ) and caused abnormal fetal megakaryopoiesis. Furthermore, cooperation between OTT-MAL and an activating mutation of the thrombopoietin receptor myeloproliferative leukemia virus oncogene (MPL) efficiently induced a short-latency AMKL that recapitulated all the features of human AMKL, including megakaryoblast hyperproliferation and maturation block, thrombocytopenia, organomegaly, and extensive fibrosis. Our results establish that concomitant activation of RBPJ (Notch signaling) and MPL (cytokine signaling) transforms cells of the megakaryocytic lineage and suggest that specific targeting of these pathways could be of therapeutic value for human AMKL. PMID:19287095

Clinical radiobiology of stage T2-T3 bladder cancer.

PubMed

Majewski, Wojciech; Maciejewski, Boguslaw; Majewski, Stanislaw; Suwinski, Rafal; Miszczyk, Leszek; Tarnawski, Rafal

2004-09-01

To evaluate the relationship between total radiation dose and overall treatment time (OTT) with the treatment outcome, with adjustment for selected clinical factors, in patients with Stage T2-T3 bladder cancer treated with curative radiotherapy (RT). The analysis was based on 480 patients with Stage T2-T3 bladder cancer who were treated at the Center of Oncology in Gliwice between 1975 and 1995. The mean total radiation dose was 65.5 Gy, and the mean OTT was 51 days. In 261 patients (54%), planned and unplanned gaps occurred during RT. Four fractionation schedules were used: (1) conventional fractionation (once daily, 1.8-2.5 Gy/fraction); (2) protracted fractionation (pelvic RT, once daily, 1.6-1.7 Gy/fraction, boost RT, once daily, 2.0 Gy/fraction); (3) accelerated hyperfractionated boost (pelvic RT, once daily, 2.0 Gy/fraction; boost RT, twice daily, 1.3-1.4 Gy/fraction); and (4) accelerated hyperfractionation (pelvic and boost RT, twice daily, 1.2-1.5 Gy/fraction). In all fractionation schedules, the total radiation dose was similar (average 65.5 Gy), but the OTT was different (mean 53 days for conventional fractionation, 62 days for protracted fractionation, 45 days for accelerated hyperfractionated boost, and 41 days for accelerated hyperfractionation). A Cox proportional hazard model and maximum likelihood logistic model were used to evaluate the relationship between the treatment-related parameters (total radiation dose, dose per fraction, and OTT) and clinical factors (clinical T stage, hemoglobin level and bladder capacity before RT) and treatment outcome. With a median follow-up of 76 months, the actuarial 5-year local control rate was 47%, and the overall survival rate was 40%. The logistic analysis, which included the total dose, OTT, and T stage, revealed that all of these factors were significantly related to tumor control probability (p = 0.021 for total radiation dose, p = 0.038 for OTT, and p = 0.00068 for T stage). A multivariate Cox model, which included the treatment-related parameters and other clinical factors, revealed that the hemoglobin level and bladder capacity before RT and T-stage were statistically significant factors determining local control and overall survival. The total radiation dose was of borderline statistical significance for overall survival (p = 0.087), and OTT did not reach statistical significance. The results of our study showed that the treatment outcome after RT for bladder cancer depends mainly on clinical factors: hemoglobin level and bladder capacity before RT, and clinical T stage. An increase in the total radiation dose seemed to be associated with a better treatment outcome. The effect of the OTT was difficult to define, because it was influenced by other prognostic factors.

Average activity of excitatory and inhibitory neural populations

NASA Astrophysics Data System (ADS)

Roulet, Javier; Mindlin, Gabriel B.

2016-09-01

We develop an extension of the Ott-Antonsen method [E. Ott and T. M. Antonsen, Chaos 18(3), 037113 (2008)] that allows obtaining the mean activity (spiking rate) of a population of excitable units. By means of the Ott-Antonsen method, equations for the dynamics of the order parameters of coupled excitatory and inhibitory populations of excitable units are obtained, and their mean activities are computed. Two different excitable systems are studied: Adler units and theta neurons. The resulting bifurcation diagrams are compared with those obtained from studying the phenomenological Wilson-Cowan model in some regions of the parameter space. Compatible behaviors, as well as higher dimensional chaotic solutions, are observed. We study numerical simulations to further validate the equations.

Average activity of excitatory and inhibitory neural populations

PubMed Central

Mindlin, Gabriel B.

2016-01-01

We develop an extension of the Ott-Antonsen method [E. Ott and T. M. Antonsen, Chaos 18(3), 037113 (2008)] that allows obtaining the mean activity (spiking rate) of a population of excitable units. By means of the Ott-Antonsen method, equations for the dynamics of the order parameters of coupled excitatory and inhibitory populations of excitable units are obtained, and their mean activities are computed. Two different excitable systems are studied: Adler units and theta neurons. The resulting bifurcation diagrams are compared with those obtained from studying the phenomenological Wilson-Cowan model in some regions of the parameter space. Compatible behaviors, as well as higher dimensional chaotic solutions, are observed. We study numerical simulations to further validate the equations. PMID:27781447

Shuttle program. MCC Level C formulation requirements: Entry guidance and entry autopilot

NASA Technical Reports Server (NTRS)

Harpold, J. C.; Hill, O.

1980-01-01

A set of preliminary entry guidance and autopilot software formulations is presented for use in the Mission Control Center (MCC) entry processor. These software formulations meet all level B requirements. Revision 2 incorporates the modifications required to functionally simulate optimal TAEM targeting capability (OTT). Implementation of this logic in the MCC must be coordinated with flight software OTT implementation and MCC TAEM guidance OTT. The entry guidance logic is based on the Orbiter avionics entry guidance software. This MCC requirements document contains a definition of coordinate systems, a list of parameter definitions for the software formulations, a description of the entry guidance detailed formulation requirements, a description of the detailed autopilot formulation requirements, a description of the targeting routine, and a set of formulation flow charts.

Peer-to-Peer Content Distribution and Over-The-Top TV: An Analysis of Value Networks

NASA Astrophysics Data System (ADS)

de Boever, Jorn; de Grooff, Dirk

The convergence of Internet and TV, i.e., the Over-The-Top TV (OTT TV) paradigm, created opportunities for P2P content distribution as these systems reduce bandwidth expenses for media companies. This resulted in the arrival of legal, commercial P2P systems which increases the importance of studying economic aspects of these business operations. This chapter examines the value networks of three cases (Kontiki, Zattoo and bittorrent) in order to compare how different actors position and distinguish themselves from competitors by creating value in different ways. The value networks of legal systems have different compositions depending on their market orientation - Business-to-Business (B2B) and/or Businessto- Consumer (B2C). In addition, legal systems differ from illegal systems as legal companies are not inclined to grant control to users, whereas users havemost control in value networks of illegal, self-organizing file sharing communities. In conclusion, the OTT TV paradigm made P2P technology a partner for the media industry rather than an enemy. However, we argue that the lack of control granted to users will remain a seed-bed for the success of illegal P2P file sharing communities.

Pitch Oscillation Data and Analysis for a Large HSCT Semispan Wing

NASA Technical Reports Server (NTRS)

Scott, Robert C.; Silva, Walter A.

2003-01-01

Data from wind-tunnel tests of the Rigid Semispan Model are presented. The primary focus is on data obtained from testing on the Oscillating Turntable (OTT), The OTT is capable of oscillating models in pitch at various amplitudes and frequencies about mean angles of attack. Steady and unsteady pressure data is presented and compared to data from previous tests on a load balance and on a Pitch and Plunge Apparatus (PAPA).

First occurrence of Nemobiinae crickets in the Lesser Antilles (Orthoptera, Grylloidea, Trigonidiidae), with the descriptions of three new species.

PubMed

Desutter-Grandcolas, Laure; Hugel, Sylvain

2016-09-15

The occurrence of Nemobiinae crickets (Grylloidea, Trigonidiidae) in the Lesser Antilles is attested here for the first time, by the descriptions of three new species of Absonemobius Desutter-Grandcolas, 1993 from Guadeloupe, St. Lucia and St. Vincent: Absonemobius septentrion n. sp., Absonemobius lucensis n. sp. and Absonemobius vincenti n. sp., and the discovery of Hygronemobius Hebard, 1913 in Guadeloupe. The generic attribution of several nemobiine species described from the Caribbean and from Southern Central America are also reviewed: Nemobius elegans Otte, 2006 from Costa Rica and Pteronemobius sanaco Otte & Perez-Gelabert, 2009 described from Belize are transferred to Hygronemobius; Hygronemobius darienicus Hebard, 1913 described from Panama is transferred to Absonemobius Desutter-Grandcolas, 1993; Hygronemobius epia Otte & Perez-Gelabert, 2009 does not belong to Hygronemobius, but is temporarily kept in this genus as incertae sedis.

A prospective study: current problems in radiotherapy for nasopharyngeal carcinoma in yogyakarta, indonesia.

PubMed

Stoker, Sharon D; Wildeman, Maarten A; Fles, Renske; Indrasari, Sagung R; Herdini, Camelia; Wildeman, Pieter L; van Diessen, Judi N A; Tjokronagoro, Maesadji; Tan, I Bing

2014-01-01

Nasopharyngeal carcinoma (NPC) has a high incidence in Indonesia. Previous study in Yogyakarta revealed a complete response of 29% and a median overall survival of less than 2 years. These poor treatment outcome are influenced by the long diagnose-to-treatment interval to radiotherapy (DTI) and the extended overall treatment time of radiotherapy (OTT). This study reveals insight why the OTT and DTI are prolonged. All patients treated with curative intent radiotherapy for NPC between July 2011 until October 2012 were included. During radiotherapy a daily diary was kept, containing information on DTI, missed radiotherapy days, the reason for missing and length of OTT. Sixty-eight patients were included. The median DTI was 106 days (95% CI: 98-170). Fifty-nine patients (87%) finished the treatment. The median OTT for radiotherapy was 57 days (95% CI: 57-65). The main reason for missing days was an inoperative radiotherapy machine (36%). Other reasons were patient's poor condition (21%), public holidays (14%), adjustment of the radiation field (7%), power blackout (3%), inoperative treatment planning system (2%) and patient related reasons (9%). Patient's insurance type was correlated to DTI in disadvantage for poor people. Yogyakarta has a lack of sufficient radiotherapy units which causes a delay of 3-4 months, besides the OTT is extended by 10-12 days. This influences treatment outcome to a great extend. The best solution would be creating sufficient radiotherapy units and better management in health care for poor patients. The growing economy in Indonesia will expectantly in time enable these solutions, but in the meantime solutions are needed. Solutions can consist of radiation outside office hours, better maintenance of the facilities and more effort from patient, doctor and nurse to finish treatment in time. These results are valuable when improving cancer care in low and middle income countries.

A Crowdsensing Based Analytical Framework for Perceptional Degradation of OTT Web Browsing.

PubMed

Li, Ke; Wang, Hai; Xu, Xiaolong; Du, Yu; Liu, Yuansheng; Ahmad, M Omair

2018-05-15

Service perception analysis is crucial for understanding both user experiences and network quality as well as for maintaining and optimizing of mobile networks. Given the rapid development of mobile Internet and over-the-top (OTT) services, the conventional network-centric mode of network operation and maintenance is no longer effective. Therefore, developing an approach to evaluate and optimizing users' service perceptions has become increasingly important. Meanwhile, the development of a new sensing paradigm, mobile crowdsensing (MCS), makes it possible to evaluate and analyze the user's OTT service perception from end-user's point of view other than from the network side. In this paper, the key factors that impact users' end-to-end OTT web browsing service perception are analyzed by monitoring crowdsourced user perceptions. The intrinsic relationships among the key factors and the interactions between key quality indicators (KQI) are evaluated from several perspectives. Moreover, an analytical framework of perceptional degradation and a detailed algorithm are proposed whose goal is to identify the major factors that impact the perceptional degradation of web browsing service as well as their significance of contribution. Finally, a case study is presented to show the effectiveness of the proposed method using a dataset crowdsensed from a large number of smartphone users in a real mobile network. The proposed analytical framework forms a valuable solution for mobile network maintenance and optimization and can help improve web browsing service perception and network quality.

Comparison of precipitation measurements by OTT Parsivel2 and Thies LPM optical disdrometers

NASA Astrophysics Data System (ADS)

Angulo-Martínez, Marta; Beguería, Santiago; Latorre, Borja; Fernández-Raga, María

2018-05-01

Optical disdrometers are present weather sensors with the ability of providing detailed information on precipitation such as rain intensity, radar reflectivity or kinetic energy, together with discrete information on the particle size and fall velocity distribution (PSVD) of the hydrometeors. Disdrometers constitute a step forward towards a more complete characterization of precipitation, being useful in several research fields and applications. In this article the performance of two extensively used optical disdrometers, the most recent version of OTT Parsivel2 disdrometer and Thies Clima Laser Precipitation Monitor (LPM), is evaluated. During 2 years, four collocated optical disdrometers, two Thies Clima LPM and two OTT Parsivel2, collected up to 100 000 min of data and up to 30 000 min with rain in more than 200 rainfall events, with intensities peaking at 277 mm h-1 in 1 minute. The analysis of these records shows significant differences between both disdrometer types for all integrated precipitation parameters, which can be explained by differences in the raw PSVD estimated by the two sensors. Thies LPM recorded a larger number of particles than Parsivel2 and a higher proportion of small particles than OTT Parsivel2, resulting in higher rain rates and totals and differences in radar reflectivity and kinetic energy. These differences increased greatly with rainfall intensity. Possible causes of these differences, and their practical consequences, are discussed in order to help researchers and users in the choice of sensor, and at the same time pointing out limitations to be addressed in future studies.

Measurement of Unsteady Pressure Data on a Large HSCT Semispan Wing and Comparison with Analysis

NASA Technical Reports Server (NTRS)

Scott, Robert C.; Silva, Walter A.; Florance, James R.; Keller, Donald F.

2002-01-01

Experimental data from wind-tunnel tests of the Rigid Semispan Model (RSM) performed at NASA Langley's Transonic Dynamics Tunnel (TDT) are presented. The primary focus of the paper is on data obtained from testing of the RSM on the Oscillating Turntable (OTT). The OTT is capable of oscillating models in pitch at various amplitudes and frequencies about mean angles of attack. Steady and unsteady pressure data obtained during testing of the RSM on the OTT is presented and compared to data obtained from previous tests of the RSM on a load balance and on a Pitch and Plunge Apparatus (PAPA). Testing of the RSM on the PAPA resulted in utter boundaries that were strongly dependent on angle of attack across the Mach number range. Pressure data from all three tests indicates the existence of vortical flows at moderate angles of attack. The correlation between the vortical flows and the unusual utter boundaries from the RSM/PAPA test is discussed. Comparisons of experimental data with analyses using the CFL3Dv6 computational fluid dynamics code are presented.

Turbulence in the Ott-Antonsen equation for arrays of coupled phase oscillators

NASA Astrophysics Data System (ADS)

Wolfrum, M.; Gurevich, S. V.; Omel'chenko, O. E.

2016-02-01

In this paper we study the transition to synchrony in an one-dimensional array of oscillators with non-local coupling. For its description in the continuum limit of a large number of phase oscillators, we use a corresponding Ott-Antonsen equation, which is an integro-differential equation for the evolution of the macroscopic profiles of the local mean field. Recently, it was reported that in the spatially extended case at the synchronisation threshold there appear partially coherent plane waves with different wave numbers, which are organised in the well-known Eckhaus scenario. In this paper, we show that for Kuramoto-Sakaguchi phase oscillators the phase lag parameter in the interaction function can induce a Benjamin-Feir-type instability of the partially coherent plane waves. The emerging collective macroscopic chaos appears as an intermediate stage between complete incoherence and stable partially coherent plane waves. We give an analytic treatment of the Benjamin-Feir instability and its onset in a codimension-two bifurcation in the Ott-Antonsen equation as well as a numerical study of the transition from phase turbulence to amplitude turbulence inside the Benjamin-Feir unstable region.

Atmospheric Transmission Modeling: Proposed Aerosol Methodology with Application to the Grafenwoehr Atmospheric Optics Data Base

DTIC Science & Technology

1976-12-01

ATMOSPHERIC OPTICS DATA BASE Robert E. Roberts December 1976 Ott 𔃾 a IDA INSTITUTE FOR DEFENSE ANALYSES 𔃾 SCIENCE AND TECHNOLOGY DIVISION 400 Army-Navy...distribu- tions, including three haze models and three cloud models, are shown in Fig. 2 for 0.7 pim and 10 um radiation. As one proceeds from the various...7 10 0.1 0.2 0.3 0.4 0.5 0.6 0.1 0.8 0.9 1.0 TRANSMISSION (8. 1-12.0 MICRONS) F.3’IGURE A-i1. Transmission in the 3.4-4.1 pim and 0.8-1.1 umn Bands

Identification of Experimental Unsteady Aerodynamic Impulse Responses

NASA Technical Reports Server (NTRS)

Silva, Walter A.; Piatak, David J.; Scott, Robert C.

2003-01-01

The identification of experimental unsteady aerodynamic impulse responses using the Oscillating Turntable (OTT) at NASA Langley's Transonic Dynamics Tunnel (TDT) is described. Results are presented for two configurations: a Rigid Semispan Model (RSM) and a rectangular wing with a supercritical airfoil section. Both models were used to acquire unsteady pressure data due to pitching oscillations on the OTT. A deconvolution scheme involving a step input in pitch and the resultant step response in pressure, for several pressure transducers, is used to identify the pressure impulse responses. The identified impulse responses are then used to predict the pressure response due to pitching oscillations at several frequencies. Comparisons with the experimental data are presented.

Creating an automated tool for measuring software cohesion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tutton, J.M.; Zucconi, L.

1994-05-06

Program modules with high complexity tend to be more error prone and more difficult to understand. These factors increase maintenance and enhancement costs. Hence, a tool that can help programmers determine a key factor in module complexity should be very useful. Our goal is to create a software tool that will automatically give a quantitative measure of the cohesiveness of a given module, and hence give us an estimate of the {open_quotes}maintainability{close_quotes} of that module. The Tool will use a metric developed by Professors Linda M. Ott and James M. Bieman. The Ott/Bieman metric gives quantitative measures that indicate themore » degree of functional cohesion using abstract data slices.« less

Two nonlinear control schemes contrasted on a hydrodynamiclike model

NASA Technical Reports Server (NTRS)

Keefe, Laurence R.

1993-01-01

The principles of two flow control strategies, those of Huebler (Luescher and Huebler, 1989) and of Ott et al. (1990) are discussed, and the two schemes are compared for their ability to control shear flow, using fully developed and transitional solutions of the Ginzburg-Landau equation as models for such flows. It was found that the effectiveness of both methods in obtaining control of fully developed flows depended strongly on the 'distance' in state space between the uncontrolled flow and goal dynamics. There were conceptual difficulties in applying the Ott et al. method to transitional convectively unstable flows. On the other hand, the Huebler method worked well, within certain limitations, although at a large cost in energy terms.

Battery testing at Argonne National Laboratory

NASA Astrophysics Data System (ADS)

Deluca, W. H.; Gillie, K. R.; Kulaga, J. E.; Smaga, J. A.; Tummillo, A. F.; Webster, C. E.

1993-03-01

Argonne National Laboratory's Analysis & Diagnostic Laboratory (ADL) tests advanced batteries under simulated electric and hybrid vehicle operating conditions. The ADL facilities also include a post-test analysis laboratory to determine, in a protected atmosphere if needed, component compositional changes and failure mechanisms. The ADL provides a common basis for battery performance characterization and life evaluations with unbiased application of tests and analyses. The battery evaluations and post-test examinations help identify factors that limit system performance and life and the most-promising R&D approaches for overcoming these limitations. Since 1991, performance characterizations and/or life evaluations have been conducted on eight battery technologies: Na/S, Li/S, Zn/Br, Ni/MH, Ni/Zn, Ni/Cd, Ni/Fe, and lead-acid. These evaluations were performed for the Department of Energy's. Office of Transportation Technologies, Electric and Hybrid Propulsion Division (DOE/OTT/EHP), and Electric Power Research Institute (EPRI) Transportation Program. The results obtained are discussed.

PLUMEX I: Coincident Radar and Rocket Observations of Equatorial Spread-F.

DTIC Science & Technology

1980-03-17

SCLmS1RESTOw, VA. 2n"g fIC? ArTN PIm KIM L10I@ICY ATN W14~ PAT C~aSIc ? A T T N C O D E A k io J A MCS A T. O sI w a C LA R K wATNOS .JISU NL# ICY...AG CY SICY ATTN OYC CAPT J. MARY PT. NqtD~ulr.J 07703 SICY ATTN DoC JOH A. 9Aq SICY ATTN OCCUENT CONTROL SICY ATTN OTT CAT HAM A. PRY SICY ATTN DES IAJ...CA 9550 OC T ATTN A. B. IAZZARI 0iCr ATTN OX: CON POP TEO IW OEPT OICY ATTN DOC CON POP L-309 R. OTT EADQUARTERS ICY A"T DOC CON FO L-51 I

Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials.

PubMed

Lees, Kennedy R; Bluhmki, Erich; von Kummer, Rüdiger; Brott, Thomas G; Toni, Danilo; Grotta, James C; Albers, Gregory W; Kaste, Markku; Marler, John R; Hamilton, Scott A; Tilley, Barbara C; Davis, Stephen M; Donnan, Geoffrey A; Hacke, Werner; Allen, Kathryn; Mau, Jochen; Meier, Dieter; del Zoppo, Gregory; De Silva, D A; Butcher, K S; Parsons, M W; Barber, P A; Levi, C; Bladin, C; Byrnes, G

2010-05-15

Early administration of intravenous recombinant tissue plasminogen activator (rt-PA) after ischaemic stroke improves outcome. Previous analysis of combined data from individual patients suggested potential benefit beyond 3 h from stroke onset. We re-examined the effect of time to treatment with intravenous rt-PA (alteplase) on therapeutic benefit and clinical risk by adding recent trial data to the analysis. We added data from ECASS III (821 patients) and EPITHET (100 patients) to a pool of common data elements from six other trials of alteplase for acute stroke (2775 patients). We used multivariate logistic regression to assess the relation of stroke onset to start of treatment (OTT) with treatment on favourable 3-month outcome (defined as modified Rankin score 0-1), mortality, and occurrence and outcome of clinically relevant parenchymal haemorrhage. The presence of an arterial occlusion was inferred from the patient's symptoms and absence of haemorrhage or other causes of ischaemic stroke. Vascular imaging was not a requirement in the trials. All patients with confirmed OTT within 360 min were included in the analysis. Treatment was started within 360 min of stroke onset in 3670 patients randomly allocated to alteplase (n=1850) or to placebo (n=1820). Odds of a favourable 3-month outcome increased as OTT decreased (p=0.0269) and no benefit of alteplase treatment was seen after around 270 min. Adjusted odds of a favourable 3-month outcome were 2.55 (95% CI 1.44-4.52) for 0-90 min, 1.64 (1.12-2.40) for 91-180 min, 1.34 (1.06-1.68) for 181-270 min, and 1.22 (0.92-1.61) for 271-360 min in favour of the alteplase group. Large parenchymal haemorrhage was seen in 96 (5.2%) of 1850 patients assigned to alteplase and 18 (1.0%) of 1820 controls, with no clear relation to OTT (p=0.4140). Adjusted odds of mortality increased with OTT (p=0.0444) and were 0.78 (0.41-1.48) for 0-90 min, 1.13 (0.70-1.82) for 91-180 min, 1.22 (0.87-1.71) for 181-270 min, and 1.49 (1.00-2.21) for 271-360 min. Patients with ischaemic stroke selected by clinical symptoms and CT benefit from intravenous alteplase when treated up to 4.5 h. To increase benefit to a maximum, every effort should be taken to shorten delay in initiation of treatment. Beyond 4.5 h, risk might outweigh benefit. None. Copyright 2010 Elsevier Ltd. All rights reserved.

Continued Development and Improvement of Pneumatic Heavy Vehicles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robert J. Englar

2005-07-15

The objective of this applied research effort led by Georgia Tech Research Institute is the application of pneumatic aerodynamic technology previously developed and patented by us to the design of an appropriate Heavy Vehicle (HV) tractor-trailer configuration, and experimental confirmation of this pneumatic configuration's improved aerodynamic characteristics. In Phases I to IV of our previous DOE program (Reference 1), GTRI has developed, patented, wind-tunnel tested and road-tested blown aerodynamic devices for Pneumatic Heavy Vehicles (PHVs) and Pneumatic Sports Utility Vehicles (PSUVs). To further advance these pneumatic technologies towards HV and SUV applications, additional Phase V tasks were included in themore » first year of a continuing DOE program (Reference 2). Based on the results of the Phase IV full-scale test programs, these Phase V tasks extended the application of pneumatic aerodynamics to include: further economy and performance improvements; increased aerodynamic stability and control; and safety of operation of Pneumatic HVs. Continued development of a Pneumatic SUV was also conducted during the Phase V program. Phase V was completed in July, 2003; its positive results towards development and confirmation of this pneumatic technology are reported in References 3 and 4. The current Phase VI of this program was incrementally funded by DOE in order to continue this technology development towards a second fuel economy test on the Pneumatic Heavy Vehicle. The objectives of this current Phase VI research and development effort (Ref. 5) fall into two categories: (1) develop improved pneumatic aerodynamic technology and configurations on smaller-scale models of the advanced Pneumatic Heavy Vehicle (PHV); and based on these findings, (2) redesign, modify, and re-test the modified full-scale PHV test vehicle. This second objective includes conduct of an on-road preliminary road test of this configuration to prepare it for a second series of SAE Type-U fuel economy evaluations, as described in Ref. 5. Both objectives are based on the pneumatic technology already developed and confirmed for DOE OHVT/OAAT in Phases I-V. This new Phase VI effort was initiated by contract amendment to the Phase V effort using carryover FY02 funds. This were conducted under a new and distinct project number, GTRI Project A-6935, separate from the Phase I-IV program. However, the two programs are closely integrated, and thus Phase VI continues with the previous program and goals.« less

Sloshing Star Goes Supernova

NASA Image and Video Library

2014-02-19

NuSTAR has provided the first observational evidence in support of a theory that says exploding stars slosh around before detonating. That theory, referred to as mild asymmetries, is shown here in a simulation by Christian Ott.

Effects of NMDA receptor blockade during the early development period on the retest performance of adult Wistar rats in the elevated plus maze.

PubMed

Kocahan, Sayad; Akillioglu, Kubra

2013-07-01

The elevated plus maze (EPM) is an animal model of anxiety used to test the effects of anxioselective drugs. The loss of the anxiolytic effect of drugs during the second exposure to the EPM is called the "one trial tolerance" (OTT) phenomenon. The present study was designed to investigate the relationship between the OTT phenomenon and N-methyl-D-aspartate (NMDA) receptor blockade in the early developmental period of rats. NMDA receptor blockade was accomplished using MK-801 treatment given between postnatal days 20-30. Beginning on postnatal day 20, the rats were subcutaneously injected with MK-801 twice a day at the nape of the neck for a period of 10 days (0.25 mg/kg). Increased open arm exploration was observed in MK-801-treated rats during trial 1 (p = 0.001) and trial 2 (p = 0.003). The rats spent less time in the closed arms as compared to the saline animals in trial 1 (p = 0.006), and this time decreased further in trial 2 (p = 0.02). The fecal boli of the MK-801 group was decreased in trial 1 as compared to the saline group (p = 0.01), but was not significantly different in trial 2 (p = 0.08). In conclusion, NMDA receptor blockade using MK-801 produced an anxiolytic-like effect in trials 1 and 2. Furthermore, OTT was not affected by NMDA receptor blockade.

Ecological Requirements of Chigger Mites.

DTIC Science & Technology

1982-03-31

our mature forest sites were in riverbottom hardwood forest, dominated by Acer negundo, Betula nigra and Liquidambar styraciflua with DBH greater than...Res. Malaysia , 16:1-67. Nutting, W. R. 1968. Host specificity in parasitic acarines. Acarolgia 10:165-180. Ott, Lyman. 1977. An introduction to

Linearized mathematical models for De Havilland Canada "Buffalo & Twin Otter" STOL transports.

DOT National Transportation Integrated Search

1971-06-01

Linearized six degree of freedom rigid body aircraft equations of motion are presented in a stability axes system. Values of stability derivatives are estimated for two representative STOL aircraft - the DeHavilland of Canada 'Buffalo' and 'Twin Otte...

The importance of immunohistochemical expression of EGFr in squamous cell carcinoma of the oral cavity treated with surgery and postoperative radiotherapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smid, Ernst J.; Stoter, T. Rianne; Bloemena, Elisabeth

2006-08-01

Purpose: The aim of this study was to investigate the prognostic significance of epidermal growth factor (EGFr) expression in oral cavity squamous cell carcinoma (OCSCC) treated with curative surgery and postoperative radiotherapy. Methods and Materials: This retrospective study included 165 OCSCC patients. The expression of EGFr was assessed on paraffin-embedded tissue of the primary tumor by immunohistochemistry using a monoclonal antibody directed against EGFr. Intensity of the EGFr expression was scored by two authors blinded for the clinical outcome. Results: In the univariate analysis, locoregional control at 3 years (LRC) in the EGFr-negative cases was 69% compared with 77% inmore » the EGFr-positive cases (p 0.22). In the multivariate analysis for local control, a significant interaction was found between EGFr and overall treatment time of radiation (OTT). After stratification for EGFr expression, the OTT was of no importance in the EGFr-negative cases, whereas a significant difference in LRC was found in the EGFr-positive cases, in which the LRC after 3 years was 69% and 94% in case of an OTT of 0-42 days and >42 days, respectively (p = 0.009; hazard ratio = 3.42; 95% confidence interval, 1.28-8.96). No significant association was found between EGFr expression and overall survival. Conclusions: In the present study, no association was found between EGFr expression and outcome regarding locoregional control and overall survival. However, the results of the present study suggest that patients with squamous cell carcinoma of the oral cavity with high EGFr expression benefit more from a reduction of the overall treatment time of postoperative radiation than those with low EGFr expression.« less

Thrombolysis in Acute Ischemic Stroke: A Simulation Study to Improve Pre- and in-Hospital Delays in Community Hospitals

PubMed Central

Lahr, Maarten M. H.; van der Zee, Durk-Jouke; Vroomen, Patrick C. A. J.; Luijckx, Gert-Jan; Buskens, Erik

2013-01-01

Background Various studies demonstrate better patient outcome and higher thrombolysis rates achieved by centralized stroke care compared to decentralized care, i.e. community hospitals. It remains largely unclear how to improve thrombolysis rate in decentralized care. The aim of this simulation study was to assess the impact of previously identified success factors in a central model on thrombolysis rates and patient outcome when implemented for a decentral model. Methods Based on a prospectively collected dataset of 1084 ischemic stroke patients, simulation was used to replicate current practice and estimate the effect of re-organizing decentralized stroke care to resemble a centralized model. Factors simulated included symptom onset call to help, emergency medical services transportation, and in-hospital diagnostic workup delays. Primary outcome was proportion of patients treated with thrombolysis; secondary endpoints were good functional outcome at 90 days, Onset-Treatment-Time (OTT), and OTT intervals, respectively. Results Combining all factors might increase thrombolysis rate by 7.9%, of which 6.6% ascribed to pre-hospital and 1.3% to in-hospital factors. Good functional outcome increased by 11.4%, 8.7% ascribed to pre-hospital and 2.7% to in-hospital factors. The OTT decreased 17 minutes, 7 minutes ascribed to pre-hospital and 10 minutes to in-hospital factors. An increase was observed in the proportion thrombolyzed within 1.5 hours; increasing by 14.1%, of which 5.6% ascribed to pre-hospital and 8.5% to in-hospital factors. Conclusions Simulation technique may target opportunities for improving thrombolysis rates in acute stroke. Pre-hospital factors proved to be the most promising for improving thrombolysis rates in an implementation study. PMID:24260151

"Mind the gap"--the impact of variations in the duration of the treatment gap and overall treatment time in the first UK Anal Cancer Trial (ACT I).

PubMed

Glynne-Jones, Rob; Sebag-Montefiore, David; Adams, Richard; McDonald, Alec; Gollins, Simon; James, Roger; Northover, John M A; Meadows, Helen M; Jitlal, Mark

2011-12-01

The United Kingdom Coordinating Committee on Cancer Research anal cancer trial demonstrated the benefit of combined modality treatment (CMT) using radiotherapy (RT), infusional 5-fluorouracil, and mitomycin C over RT alone. The present study retrospectively examines the impact of the recommended 6-week treatment gap and local RT boost on long-term outcome. A total of 577 patients were randomly assigned RT alone or CMT. After a 6-week gap responders received a boost using either additional external beam radiotherapy (EBRT) (15 Gy) or iridium-192 implant (25 Gy). The effect of boost, the gap between initial treatment (RT alone or CMT) and boost (Tgap), and overall treatment time (OTT) were examined for their impact on outcome. Among the 490 good responders, 436 (89%) patients received a boost after initial treatment. For boosted patients, the risk of anal cancer death decreased by 38% (hazard ratio [HR]: 0.62, 99% CI 0.35-1.12; p=0.04), but there was no evidence this was mediated via a reduction in locoregional failure (LRF) (HR: 0.90, 99% CI 0.48-1.68; p=0.66). The difference in Tgap was only 1.4 days longer for EBRT boost, compared with implant (p=0.51). OTT was longer by 6.1 days for EBRT (p=0.006). Tgap and OTT were not associated with LRF. Radionecrosis was reported in 8% of boosted, compared with 0% in unboosted patients (p=0.03). These results question the benefit of a radiotherapy boost after a 6-week gap. The higher doses of a boost may contribute more to an increased risk of late morbidity, rather than local control. Copyright © 2011 Elsevier Inc. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Glynne-Jones, Rob, E-mail: rob.glynnejones@nhs.net; Sebag-Montefiore, David; Adams, Richard

Purpose: The United Kingdom Coordinating Committee on Cancer Research anal cancer trial demonstrated the benefit of combined modality treatment (CMT) using radiotherapy (RT), infusional 5-fluorouracil, and mitomycin C over RT alone. The present study retrospectively examines the impact of the recommended 6-week treatment gap and local RT boost on long-term outcome. Methods and Materials: A total of 577 patients were randomly assigned RT alone or CMT. After a 6-week gap responders received a boost using either additional external beam radiotherapy (EBRT) (15 Gy) or iridium-192 implant (25 Gy). The effect of boost, the gap between initial treatment (RT alone ormore » CMT) and boost (Tgap), and overall treatment time (OTT) were examined for their impact on outcome. Results: Among the 490 good responders, 436 (89%) patients received a boost after initial treatment. For boosted patients, the risk of anal cancer death decreased by 38% (hazard ratio [HR]: 0.62, 99% CI 0.35-1.12; p = 0.04), but there was no evidence this was mediated via a reduction in locoregional failure (LRF) (HR: 0.90, 99% CI 0.48-1.68; p = 0.66). The difference in Tgap was only 1.4 days longer for EBRT boost, compared with implant (p = 0.51). OTT was longer by 6.1 days for EBRT (p = 0.006). Tgap and OTT were not associated with LRF. Radionecrosis was reported in 8% of boosted, compared with 0% in unboosted patients (p = 0.03). Conclusions: These results question the benefit of a radiotherapy boost after a 6-week gap. The higher doses of a boost may contribute more to an increased risk of late morbidity, rather than local control.« less

Evaluation of the New Version of the Laser-Optical Disdrometer, OTT Parsivel2

NASA Technical Reports Server (NTRS)

Tokay, Ali; Wolff, David B.; Petersen, Walter A.

2014-01-01

A comparative study of raindrop size distribution measurements has been conducted at NASA's Goddard Space Flight Center where the focus was to evaluate the performance of the upgraded laser-optical OTT Particle Size Velocity (Parsivel2; P2) disdrometer. The experimental setup included a collocated pair of tipping-bucket rain gauges, OTT Parsivel (P1) and P2 disdrometers, and Joss-Waldvogel (JW) disdrometers. Excellent agreement between the two collocated rain gauges enabled their use as a relative reference for event rain totals. A comparison of event total showed that the P2 had a 6%absolute bias with respect to the reference gauges, considerably lower than the P1 and JW disdrometers. Good agreement was also evident between the JW and P2 in hourly raindrop spectra for drop diameters between 0.5 and 4 mm. The P2 drop concentrations mostly increased toward small sizes, and the peak concentrations were mostly observed in the first three measurable size bins. The P1, on the other hand, underestimated small drops and overestimated the large drops, particularly in heavy rain rates. From the analysis performed, it appears that the P2 is an improvement over the P1 model for both drop size and rainfall measurements. P2 mean fall velocities follow accepted terminal fall speed relationships at drop sizes less than 1 mm. As a caveat, the P2 had approximately 1ms21 slower mean fall speed with respect to the terminal fall speed near 1 mm, and the difference between the mean measured and terminal fall speeds reduced with increasing drop size. This caveat was recognized as a software bug by the manufacturer and is currently being investigated.

Superfund record of decision amendment (EPA Region 5): Ott/Story/Cordova Chemical Co., Dalton Township, MI, February 26, 1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This decision document presents the amendment to the Record of Decision (ROD) for Operable Unit (O.U.) No. 3 at the Ott/Story/Cordova Site (the Site) in Muskegon, MI. On September 27, 1993 a ROD was signed for the O.U. No. 3 Remedial Action choosing Low Temperature Thermal Desorption (LTTD) to treat contaminated plant area soils and sediments in Little Bear Creek and its unnamed tributary. This amendment to the ROD: eliminates LTTD from the remedy; revises the volume of soils to be remediated by excavation and off-site disposal as a result of an understanding that the land use for the sitemore » will remain industrial instead of residential as provided for in the 1993 ROD; requires regular sampling of surface water and sediments to determine the need for remedial action in the Little Bear Creek; and requires deed restrictions to insure that use of the site remains industrial.« less

Controlling thermal emission with refractory epsilon-near-zero metamaterials via topological transitions

NASA Astrophysics Data System (ADS)

Dyachenko, P. N.; Molesky, S.; Petrov, A. Yu; Störmer, M.; Krekeler, T.; Lang, S.; Ritter, M.; Jacob, Z.; Eich, M.

2016-06-01

Control of thermal radiation at high temperatures is vital for waste heat recovery and for high-efficiency thermophotovoltaic (TPV) conversion. Previously, structural resonances utilizing gratings, thin film resonances, metasurfaces and photonic crystals were used to spectrally control thermal emission, often requiring lithographic structuring of the surface and causing significant angle dependence. In contrast, here, we demonstrate a refractory W-HfO2 metamaterial, which controls thermal emission through an engineered dielectric response function. The epsilon-near-zero frequency of a metamaterial and the connected optical topological transition (OTT) are adjusted to selectively enhance and suppress the thermal emission in the near-infrared spectrum, crucial for improved TPV efficiency. The near-omnidirectional and spectrally selective emitter is obtained as the emission changes due to material properties and not due to resonances or interference effects, marking a paradigm shift in thermal engineering approaches. We experimentally demonstrate the OTT in a thermally stable metamaterial at high temperatures of 1,000 °C.

Controlling thermal emission with refractory epsilon-near-zero metamaterials via topological transitions

PubMed Central

Dyachenko, P. N.; Molesky, S.; Petrov, A. Yu; Störmer, M.; Krekeler, T.; Lang, S.; Ritter, M.; Jacob, Z.; Eich, M.

2016-01-01

Control of thermal radiation at high temperatures is vital for waste heat recovery and for high-efficiency thermophotovoltaic (TPV) conversion. Previously, structural resonances utilizing gratings, thin film resonances, metasurfaces and photonic crystals were used to spectrally control thermal emission, often requiring lithographic structuring of the surface and causing significant angle dependence. In contrast, here, we demonstrate a refractory W-HfO2 metamaterial, which controls thermal emission through an engineered dielectric response function. The epsilon-near-zero frequency of a metamaterial and the connected optical topological transition (OTT) are adjusted to selectively enhance and suppress the thermal emission in the near-infrared spectrum, crucial for improved TPV efficiency. The near-omnidirectional and spectrally selective emitter is obtained as the emission changes due to material properties and not due to resonances or interference effects, marking a paradigm shift in thermal engineering approaches. We experimentally demonstrate the OTT in a thermally stable metamaterial at high temperatures of 1,000 °C. PMID:27263653

Analysis on Patterns of Globally Coupled Phase Oscillators with Attractive and Repulsive Interactions

NASA Astrophysics Data System (ADS)

Wang, Peng-Fei; Ruan, Xiao-Dong; Xu, Zhong-Bin; Fu, Xin

2015-11-01

The Hong-Strogatz (HS) model of globally coupled phase oscillators with attractive and repulsive interactions reflects the fact that each individual (oscillator) has its own attitude (attractive or repulsive) to the same environment (mean field). Previous studies on HS model focused mainly on the stable states on Ott-Antonsen (OA) manifold. In this paper, the eigenvalues of the Jacobi matrix of each fixed point in HS model are explicitly derived, with the aim to understand the local dynamics around each fixed point. Phase transitions are described according to relative population and coupling strength. Besides, the dynamics off OA manifold is studied. Supported by the National Basic Research Program of China under Grant No. 2015CB057301, the Applied Research Project of Public Welfare Technology of Zhejiang Province under Grant No. 201SC31109 and China Postdoctoral Science Foundation under Grant No. 2014M560483

Early Adolescent Perceptions Regarding Sources of Sexual Health Information

ERIC Educational Resources Information Center

Shoemaker, Kylea K.

2017-01-01

Early adolescence includes youth approximately 11-14 years of age. This age group represents a population open to learning more information about sexuality and signifies a developmental period where effective sexuality interventions may begin (Ott & Pfieffer, 2009; Grossman et al., 2014). Early adolescence is a critical period when…

Teaching about Teaching Sexuality and Religion

ERIC Educational Resources Information Center

Stephens, Darryl W.

2017-01-01

Classroom instructors implementing pedagogical strategies for embodied learning about sexuality and religion need institutional support and assistance from colleagues and mentors to be successful. One means of providing institutional and peer support for classroom instructors is to host and lead a pedagogy workshop. Building on the work of Ott and…

Global War on Terrorism: Executing War without Unity of Command

DTIC Science & Technology

2007-03-09

41 outlined 14 principles of management , which apply to this discussion. He states, “authority and responsibility, unity of command, unity of...Fayol, “General Principles of Management ,” in Classics of Organization Theory, ed. Jay M. Shafritz, J. Steven Ott, and Yong Suk Jang (Belmont,CA

Analytical Methods in Search Theory

DTIC Science & Technology

1979-11-01

X, t ) ,I pick g(x,t;E), *(x,tjc) and find the b necessary to satisfy the search equation. SOLUTION: This is an audience participation problem. It...Cnstotiaticon G11trant,’ ’I pp 2110 Path lestegsls,’ to pp., Jun IBM Iltetteol Pepsi pp., Ott 1313 (Tt o besubmitoet lot pubtinatteon l t Messino, Daidit

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jeffries, C.; Perez, J.

For a driven nonlinear oscillator we report direct evidence for three cases of an interior crisis of the attractor, as conjectured by Grebogi, Ott, and Yorke. These crises are sudden and discontinuous changes in the attractor, observed directly from bifurcation diagrams and attractor diagrams (Poincare sections) in real time. The crises arise from intersection of an unstable orbit with the chaotic attractor.

Degrading, Devaluing and Discounting: The Qualifications of Overseas Trained Teachers (OTT) in England

ERIC Educational Resources Information Center

Miller, Paul

2008-01-01

Highly trained teachers from across the world come to England expecting to practise their chosen profession. These expectations are dashed, however, if their foreign credentials and work experience are not recognised as legitimate by potential employers and accreditation bodies. This type of social situation is the focus of the relative…

Mathematical Knowledge: Its Growth through Teaching. Mathematics Education Library, Volume 10.

ERIC Educational Resources Information Center

Bishop, Alan J., Ed.; And Others

This book presents issues concerning relationships between mathematical knowledge and the teaching and learning processes, focusing especially on the genesis of mathematical knowledge in the classroom. The chapter titles are: (1) The Fragility of Knowledge (Guy Brousseau and Michael Otte); (2) The Double Bind as a Didactical Trap (Stieg…

The Impact Analysis of a Mixed Squadron, Containing LCS and Multi-Mission Surface Platforms, on Blue Force Casualties and Mission Effectiveness

DTIC Science & Technology

2008-09-01

Littoral Combat Ships OTH Over-The-Horizon Pd Probability of Detection PGGF Fast Attack Craft – Missile PIM Plan of Intended Movement Pk...Lucas Naval Postgraduate School Monterey, California 2. Dudley Knox Library Naval Postgraduate School Monterey, California 3. CAPT Doug Otte

Prisons as Organizational Cultures: A Literature Review of a Vastly Unexplored Organizational Communication Setting.

ERIC Educational Resources Information Center

Bedore, Joan M.

This literature review examines prisons as organizations and prisons as cultures, for as J. M. Shafritz and J. S. Ott (1992) point out, "a strong organizational culture literally controls organizational behavior." The review investigates the research of prison, organizational, and communication scholars to see how prison cultures shape…

Invariant submanifold for series arrays of Josephson junctions.

PubMed

Marvel, Seth A; Strogatz, Steven H

2009-03-01

We study the nonlinear dynamics of series arrays of Josephson junctions in the large-N limit, where N is the number of junctions in the array. The junctions are assumed to be identical, overdamped, driven by a constant bias current, and globally coupled through a common load. Previous simulations of such arrays revealed that their dynamics are remarkably simple, hinting at the presence of some hidden symmetry or other structure. These observations were later explained by the discovery of N-3 constants of motion, the choice of which confines the resulting flow in phase space to a low-dimensional invariant manifold. Here we show that the dimensionality can be reduced further by restricting attention to a special family of states recently identified by Ott and Antonsen. In geometric terms, the Ott-Antonsen ansatz corresponds to an invariant submanifold of dimension one less than that found earlier. We derive and analyze the flow on this submanifold for two special cases: an array with purely resistive loading and another with resistive-inductive-capacitive loading. Our results recover (and in some instances improve) earlier findings based on linearization arguments.

Experimental Measurements in the Turbulent Boundary Layer of a Yawed, Spinning Ogive-Cylinder Body of Revolution at Mach 3.0. Part 2. Data Tabulation

DTIC Science & Technology

1978-03-01

00 000000 0 4j Q C-4W% QV I- t. W w m oxw 0 Lrfl, or ( PIm L ITIr 4.2Q 00 QIMP v CJ .ot 00𔃾 004 .40l0.,I𔃾~mI Of-C0..,4C 44Ct4.’C00O00 3OO0 OOO OO nCM...on,*"- - -4 F %a0 ,p4 I 3hf Ott a3 1-~ 4’ 4 .0 0% rdI03I03:o3m 0, "~�P0 02I2nC LI1 ~ TC. . 000~~ 000 000 00Q 0 0 00 01- 004 s,0 .0 00000 00...1 I# .4 7 jL" qifA . , 4w .4-4-y4..4 ucp .4 m w w-e- P2unjmp J. 90-9 0 ~U w 0a. O 5,. Ott ; 8p-c; 10 -:40 44414 A ;J uj 0.3 0.0~U%4%M~-t~ Mm mMMMMm

Laboratory evaluation of an OTT acoustic digital current meter and a SonTek Laboratory acoustic Doppler velocimeter

USGS Publications Warehouse

Vermeyen, T.B.; Oberg, Kevin A.; Jackson, Patrick Ryan

2009-01-01

Recently, an acoustic current meter known as the OTT * acoustic digital current meter (ADC) was introduced as an alternative instrument for stream gaging measurements. The Bureau of Reclamation and the U.S. Geological Survey collaborated on a side- by-side evaluation of the ADC and a SonTek/YSI acoustic Doppler velocimeter (ADV). Measurements were carried out in a laboratory flume to evaluate the performance characteristics of the ADC under a range of flow and boundary conditions. The flume contained a physical model of a mountain river with a diversion dam and variety of bed materials ranging from smooth mortar to a cobble bed. The instruments were installed on a trolley system that allowed them to be easily moved within the flume while maintaining a consistent probe orientation. More than 50 comparison measurements were made in an effort to verify the manufacturer’s performance specifications and to evaluate potential boundary disturbance for near-bed and vertical boundary measurements. Data and results from this evaluation are presented and discussed. 

Choices Regarding Thrombolysis Are Modified by the Way to Transfer the Messages.

PubMed

Gong, Jingjing; Zhang, Yan; Gao, Hongyan; Wei, Wei; Lv, Jing; Liu, Hongyun; Huang, Yonghua

2017-01-01

Although thrombolysis is the most effective medical treatment for acute ischemic stroke, many stroke patients eligible for thrombolysis miss this treatment as a result of delay or refusal by the patients and/or their proxies. To explore the influences of prognostic information for different intervals from stroke onset to the start of thrombolytic treatment (OTT) and other factors on the preferences of patients/proxies regarding thrombolytic therapy, a cross-sectional, discrete-choice experiment was performed between August 2013 and September 2014. A total of 613 Chinese inpatients or their immediate family members were consecutively recruited at the Department of Neurology. After random assignment to a negative-framing group or a positive-framing group, the subjects completed a series of surveys, including nine items about thrombolysis. Latent class analysis (LCA) was used to examine participants' preference paradigms for thrombolysis and to categorize the participants into different subgroups. Subsequently, regression analyses were conducted to explore predictors of categorization of the participants into each subgroup and to construct a thrombolytic decision-making model. LCA revealed an optimal 3-subgroup model including a consent to thrombolysis subgroup and objection to thrombolysis subgroups 1 and 2. Multiple regression analysis demonstrated that compared with assignment to the consent to thrombolysis subgroup, assignment to objection to thrombolysis subgroup 1 or 2 could be predicted by different factors. χ 2 tests indicated effects of framing and other factors on participants' choices regarding thrombolysis. Choices regarding thrombolysis were modified by not only prognostic information for different OTT intervals but also message framing, presentation format, and sociodemographic characteristics. To facilitate consent to thrombolysis, physicians should convey prognostic information to patients/proxies on the basis of patient OTT interval and should order the presentation of therapies according to the classification of patients/proxies. Individualized decision-making (IDM) might be an optimal strategy to increase the selection of thrombolysis, which providing important reference points for IDM in other clinical domains.

Choices Regarding Thrombolysis Are Modified by the Way to Transfer the Messages

PubMed Central

Gong, Jingjing; Zhang, Yan; Gao, Hongyan; Wei, Wei; Lv, Jing; Liu, Hongyun; Huang, Yonghua

2017-01-01

Although thrombolysis is the most effective medical treatment for acute ischemic stroke, many stroke patients eligible for thrombolysis miss this treatment as a result of delay or refusal by the patients and/or their proxies. To explore the influences of prognostic information for different intervals from stroke onset to the start of thrombolytic treatment (OTT) and other factors on the preferences of patients/proxies regarding thrombolytic therapy, a cross-sectional, discrete-choice experiment was performed between August 2013 and September 2014. A total of 613 Chinese inpatients or their immediate family members were consecutively recruited at the Department of Neurology. After random assignment to a negative-framing group or a positive-framing group, the subjects completed a series of surveys, including nine items about thrombolysis. Latent class analysis (LCA) was used to examine participants’ preference paradigms for thrombolysis and to categorize the participants into different subgroups. Subsequently, regression analyses were conducted to explore predictors of categorization of the participants into each subgroup and to construct a thrombolytic decision-making model. LCA revealed an optimal 3-subgroup model including a consent to thrombolysis subgroup and objection to thrombolysis subgroups 1 and 2. Multiple regression analysis demonstrated that compared with assignment to the consent to thrombolysis subgroup, assignment to objection to thrombolysis subgroup 1 or 2 could be predicted by different factors. χ2 tests indicated effects of framing and other factors on participants’ choices regarding thrombolysis. Choices regarding thrombolysis were modified by not only prognostic information for different OTT intervals but also message framing, presentation format, and sociodemographic characteristics. To facilitate consent to thrombolysis, physicians should convey prognostic information to patients/proxies on the basis of patient OTT interval and should order the presentation of therapies according to the classification of patients/proxies. Individualized decision-making (IDM) might be an optimal strategy to increase the selection of thrombolysis, which providing important reference points for IDM in other clinical domains. PMID:29167657

Laboratory of Viral Diseases Guest Researcher Seminar Series | Center for Cancer Research

Cancer.gov

Laboratory of Viral Diseases Guest Researcher Seminar Series New Epigenetic Regulators of HIV Latency Speaker: Melanie Ott, M.D., Ph.D, Senior Investigator & Professor of Medicine Gladstone Institutes & University of California Building 33, Main Conference Room 1N09 Main NIH CAMPUS *BLDG 33 is a secure facility, please allow time to pass through security.

Low Cost Space Experiments. Study Report

DTIC Science & Technology

1991-12-06

Air Force Phillips Laboratory with Johns Hopkins University Applied Physics Laboratory . The goals of ALTAIR...Cs<- &l. LOW COST SPACE EXPERIMENTS STUDY REPORT 6 December 1991 19980302 059 Phillips Laboratory /SXL Kirtland AFB, NM 87117-6008 TVPTT" OTT...Report Corporate Author or Publisher: Phillips Laboratory /SXL, Kirtland AFB,NM 87117-6008 Publication Date: Dec 06, 1991 Pages: 176 Comments

76 FR 11177 - Frequency Regulation Compensation in the Organized Wholesale Power Markets

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-01

... energy injected less energy withdrawn multiplied by the real-time energy price. 10. Accuracy of... lowering energy prices.\\33\\ \\32\\ Tr. 35-36 (Ott); Tr. 30-31 (Kathpal); Tr. 37-39 (Ramey). \\33\\ Id. 24. To... same price per MWh of net energy.\\39\\ Again, this could lead to providing different amounts of ACE...

Overseas Trained Teachers in England: A Policy Framework for Social and Professional Integration

ERIC Educational Resources Information Center

Miller, Paul Washington

2008-01-01

Overseas trained teachers (OTTs) have become an important part of the make-up of England's primary and secondary education system. Through inadequate, and in some cases a lack of, initial induction and support for professional development, many are at risk of performing sub-optimally and some have become an endangered species. Failure to integrate…

Alternative Fuels Data Center: Coca-Cola Bottling Co. Brings Hybrids to New

Science.gov Websites

as a great example of a viable clean transportation option for similar fleets. " Rebecca Otte commitment to a more sustainable community and serves as a great example of a viable clean transportation , individual bottling companies now operate these vehicles. For example, Coca-Cola Bottling Company United

Optical Pumping of Molecular Gases

DTIC Science & Technology

1976-04-01

ser emission ott a The typical experimental apparatus is shown i.- Fig. *series of green and yellow molecular B-X’-basnd transi- 2. For B-bantd optical...with A, at 0. 473 pim and that Na2 may operate as a flash -lamp -pumped laser X,... at 0. 54 umn the Doppler widths are AwD - 12.42 source with buffer

U.S. EPA, Pesticide Product Label, TDC DICOFOL 4E, 02/19/1982

EPA Pesticide Factsheets

2011-04-21

... kJI ~ ...-I ~ ... M<1 ~ IIrf'Ie(II.-cI -- roc D«X>fOt '·E CWI be ~ 8IIOnI or 'tII"Ith ott>.f ~~ ... t9COiI ••• ded 'Pf'-r ~ • ttIouId Ml ~ ....s wtth limit or ... y ~ tIO .-piM.! ...

Diatomaceous Fungal and Bacterial Building Blocks for Material Synthesis

DTIC Science & Technology

2008-04-08

Thalassiosira-templated metallic microshells. Thalassiosira, only 1mM rhodamine 6G (d) lmM, (e) I piM ,(f 100 nM R6G. 4 concentrations gave detectable...hybridized with a 27-mer 7 oligonucleotide containing a 7-mer TAG GAA TAG TTA TA AT OTT ATT AGO complementary region 2, which produces TAIOATCCTTA TACAATAATCC

Non-Heat Treatable Alloy Sheet Products

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hayden, H.W.; Barthold, G.W.; Das, S.K.

ALCAR is an innovative approach for conducting multi-company, pre-competitive research and development programs. ALCAR has been formed to crate a partnership of aluminum producers, the American Society of Mechanical Engineers Center for Research and Technology Development (ASME/CRTD), the United States Department of Energy (USDOE), three USDOE National Laboratories, and a Technical Advisory Committee for conducting cooperative, pre-competitive research on the development of flower-cost, non-heat treated (NHT) aluminum alloys for automotive sheet applications with strength, formability and surface appearance similar to current heat treated (HT) aluminum alloys under consideration. The effort has been supported by the USDOE, Office of Transportation Technologymore » (OTT) through a three-year program with 50/50 cost share at a total program cost of $3 million. The program has led to the development of new and modified 5000 series aluminum ally compositions. Pilot production-size ingots have bee n melted, cast, hot rolled and cold rolled. Stamping trials on samples of rolled product for demonstrating production of typical automotive components have been successful.« less

High-Performance Solid-State and Fiber Lasers Controlled by Volume Bragg Gratings

DTIC Science & Technology

2013-09-01

Glebov: Proc. SPIE 8237 (2012) 823705. 12） I. Divliansky, D. Ott, B. Anderson, G. Venus, and L. Glebov: To be published in Opt. Express. 13） A. Jain...B. Anderson, D. Drachenberg, V. Rotar, G. Venus, and L. Glebov: Proc. SPIE 8237 (2012) 823705. 47） B. Anderson, S. Kaim, G. B. Venus, J. Lumeau, V

Bilingual Education in Three Cultures, Annual Conference of the Southwest Council for Bilingual Education (El Paso, November 8-9, 1968). Reports.

ERIC Educational Resources Information Center

Olstad, Charles, Ed.

These Reports deal with the American English, Texan Spanish, and Navajo languages and cultures. "English in Bilingual Education" by Elizabeth Ott describes the history of education in the Southwest and examines the concept and many forms of bilingualism. An example of a possible bilingual instructional program is given. "The Spanish…

Modeling and Modification of the Electromagnetic Properties of Advanced Composite Materials.

DTIC Science & Technology

1980-01-01

Direction 𔃾 into x tpaper L2JI F L TRANSVERSE CONDuCTIVmf !( oDK FIGUR 1-2 ’I I _ _ _ _ _ _ _ _ _ _ _ _ _ _ T-1 14 Pe’u are the electron, hole mobilities and...Otte and Lipsitt [4]. One of the conclusions of (5] is to characterize CYD boron as a collection of small crystallites of the 3-rhombohedral form

Dynamics of heterogeneous oscillator ensembles in terms of collective variables

NASA Astrophysics Data System (ADS)

Pikovsky, Arkady; Rosenblum, Michael

2011-04-01

We consider general heterogeneous ensembles of phase oscillators, sine coupled to arbitrary external fields. Starting with the infinitely large ensembles, we extend the Watanabe-Strogatz theory, valid for identical oscillators, to cover the case of an arbitrary parameter distribution. The obtained equations yield the description of the ensemble dynamics in terms of collective variables and constants of motion. As a particular case of the general setup we consider hierarchically organized ensembles, consisting of a finite number of subpopulations, whereas the number of elements in a subpopulation can be both finite or infinite. Next, we link the Watanabe-Strogatz and Ott-Antonsen theories and demonstrate that the latter one corresponds to a particular choice of constants of motion. The approach is applied to the standard Kuramoto-Sakaguchi model, to its extension for the case of nonlinear coupling, and to the description of two interacting subpopulations, exhibiting a chimera state. With these examples we illustrate that, although the asymptotic dynamics can be found within the framework of the Ott-Antonsen theory, the transients depend on the constants of motion. The most dramatic effect is the dependence of the basins of attraction of different synchronous regimes on the initial configuration of phases.

Directed assembly of colloidal particles for micro/nano photonics (Conference Presentation)

NASA Astrophysics Data System (ADS)

Zheng, Yuebing

2017-02-01

Bottom-up fabrication of complex structures with chemically synthesized colloidal particles as building blocks pave an efficient and cost-effective way towards micro/nano photonics with unprecedented functionality and tunability. Novel properties can arise from quantum effects of colloidal particles, as well as inter-particle interactions and spatial arrangement in particle assemblies. Herein, I discuss our recent developments and applications of three types of techniques for directed assembly of colloidal particles: moiré nanosphere lithography (MNSL), bubble-pen lithography (BPL), and optothermal tweezers (OTTs). Specifically, MNSL provides an efficient approach towards creating moiré metasurface with tunable and multiband optical responses from visible to mid-infrared regime. Au moiré metasurfaces have been applied for surface-enhanced infrared spectroscopy, optical capture and patterning of bacteria, and photothermal denaturation of proteins. BPL is developed to pattern a variety of colloidal particles on plasmonic substrates and two-dimensional atomic-layer materials in an arbitrary manner. The laser-directed microbubble captures and immobilizes nanoparticles through coordinated actions of Marangoni convection, surface tension, gas pressure, and substrate adhesion. OTTs are developed to create dynamic nanoparticle assemblies at low optical power. Such nanoparticle assemblies have been used for surface-enhanced Raman spectroscopy for molecular analysis in their native environments.

Monte Carlo Simulation Modeling of a Regional Stroke Team's Use of Telemedicine.

PubMed

Torabi, Elham; Froehle, Craig M; Lindsell, Christopher J; Moomaw, Charles J; Kanter, Daniel; Kleindorfer, Dawn; Adeoye, Opeolu

2016-01-01

The objective of this study was to evaluate operational policies that may improve the proportion of eligible stroke patients within a population who would receive intravenous recombinant tissue plasminogen activator (rt-PA) and minimize time to treatment in eligible patients. In the context of a regional stroke team, the authors examined the effects of staff location and telemedicine deployment policies on the timeliness of thrombolytic treatment, and estimated the efficacy and cost-effectiveness of six different policies. A process map comprising the steps from recognition of stroke symptoms to intravenous administration of rt-PA was constructed using data from published literature combined with expert opinion. Six scenarios were investigated: telemedicine deployment (none, all, or outer-ring hospitals only) and staff location (center of region or anywhere in region). Physician locations were randomly generated based on their zip codes of residence and work. The outcomes of interest were onset-to-treatment (OTT) time, door-to-needle (DTN) time, and the proportion of patients treated within 3 hours. A Monte Carlo simulation of the stroke team care-delivery system was constructed based on a primary data set of 121 ischemic stroke patients who were potentially eligible for treatment with rt-PA. With the physician located randomly in the region, deploying telemedicine at all hospitals in the region (compared with partial or no telemedicine) would result in the highest rates of treatment within 3 hours (80% vs. 75% vs. 70%) and the shortest OTT (148 vs. 164 vs. 176 minutes) and DTN (45 vs. 61 vs. 73 minutes) times. However, locating the on-call physician centrally coupled with partial telemedicine deployment (five of the 17 hospitals) would be most cost-effective with comparable eligibility and treatment times. Given the potential societal benefits, continued efforts to deploy telemedicine appear warranted. Aligning the incentives between those who would have to fund the up-front technology investments and those who will benefit over time from reduced ongoing health care expenses will be necessary to fully realize the benefits of telemedicine for stroke care. © 2015 by the Society for Academic Emergency Medicine.

Breathing chimera in a system of phase oscillators

NASA Astrophysics Data System (ADS)

Bolotov, M. I.; Smirnov, L. A.; Osipov, G. V.; Pikovsky, A. S.

2017-09-01

Chimera states consisting of synchronous and asynchronous domains in a medium of nonlinearly coupled phase oscillators have been considered. Stationary inhomogeneous solutions of the Ott-Antonsen equation for a complex order parameter that correspond to fundamental chimeras have been constructed. The direct numerical simulation has shown that these structures under certain conditions are transformed to oscillatory (breathing) chimera regimes because of the development of instability.

Proof of the Feasibility of Coherent and Incoherent Schemes for Pumping a Gamma-Ray Laser

DTIC Science & Technology

1988-01-01

device has been well characterized, 10,11 and its outputV Gose rate has been calibrated with an accuracy of z: 3%. After irradia- A- lion, t-he samples...Takahashi, Nature, 305, 198 (1983). 4. H. Beer and R. A. Ward, Nature, 291, 308 (1981). 5. E. Runte, W. D. Schmidt-Ott, W. Eschner, I. Rosner, R. Kirchner, 0

What Does It Mean to Educate?

ERIC Educational Resources Information Center

Knausz, Imre

2016-01-01

This paper focuses on the most abstract and most boring question of pedagogy or, as I prefer to call my field of interest, the theory of pedagogy. My aim is to try to rehash and re-pose this question--maybe even answer it? In this regard, Ottó Mihály advises us to be careful; in the preface to his notes on the philosophy of pedagogy he asserts…

Applied Polarography for Analysis of Ordnance Materials. Part 1. Determination and Monitoring for 1,2-Propyleneglycoldinitrate in Effluent Water by Single-Sweep Polarography

DTIC Science & Technology

1976-06-01

ie irom Ott - Ae wastewatt:r. Data obtained by the NWC-developed method of analyds and field equipment ccupare favorably with data obtained by a vapor...5, curve &. A microaliquot of standard PIM solution is then added to the cell solution and the procedure is repeated. This is known as the standard

Three or Four Fractions of 4-5 Gy per Week in Postoperative High-Dose-Rate Brachytherapy for Endometrial Carcinoma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rovirosa, Angeles, E-mail: rovirosa@clinic.ub.es; Ascaso, Carlos; Sanchez-Reyes, Alberto

2011-10-01

Purpose: To evaluate the results of high-dose-rate brachytherapy (HDRBT) using a schedule of three or four fractions per week, when possible, in 89 patients on local control and toxicity in postoperative treatment of endometrial carcinoma. The effect of the overall HDRBT treatment time (OTT) on toxicity was also evaluated. Patients and Methods: Federation Internationale de Gynecologie Obstetrique Stage: 24 IB, 45 IC, 4 IIA, 6 IIB, 4 IIIA, 2 IIIB, and 4 IIIC. Radiotherapy: Group 1-67 of 89 patients received external beam irradiation (EBI; 44-50 Gy) plus HDRBT (3 fractions of 4-6 Gy); Group 2-22 of 89 patients received HDRBTmore » alone (6 fractions of 4-5 Gy). OTT: Group 1-HDRBT was completed in a median of 5 days in 32 patients and in >5 days in 35; Group 2-HDRBT was completed in <15 days in 11 patients and in {>=}16 days in 11. Toxicity was evaluated using Radiation Therapy Oncology Group scores and the bioequivalent dose (BED) study was performed in vaginal mucosa surface. Statistics included Student's t test, chi-square test, and receiving operator curves. Results: With a mean follow-up of 31 months (range, 6-70), 1 of 89 patients had vaginal relapse. Early toxicity appeared in 8 of 89 (9%) patients and was resolved. Late toxicity appeared in 13/89 (14%): vaginal nine Grade 1, three Grade 2, one Grade 4; bladder two Grade 2; rectal three Grade 1, one Grade 2. No differences were found in relation to OTT in Groups 1 and 2. Mean BED was 88.48 Gy in Group 1 and 165.28 Gy in Group 2. Cases with Grade 2 late vaginal toxicity received >75 Gy after EBI and >165 Gy in Group 2. Conclusions: Three fractions of 4-5 Gy in 3-5 days after EBI or 6 fractions in <15 days in patients receiving HDRBT alone was a safe treatment in relation to toxicity and local control. Vaginal surface BED less than 75 Gy after EBI and less than 160 Gy in HDRBT alone may be safe to avoid G2 toxicity.« less

Inducing Ontologies from Folksonomies using Natural Language Understanding

DTIC Science & Technology

2009-11-13

3000, Richardson, TX, 75080 Phone number: (972) 680-0800 Effective date of contract: April 28th, 2009 Short title of work: Contract expiration date...highly correlated tags. Non-trivial examples include: EQUALITY(acr/vzYy, activities), EQUALITY {after- effects , AfterEffects), and EQUALITY(opz’w’ott...This procedure added 23.66% of the total number of relations to the ontology. Examples include lSA( vegan , vegetarian), ANTONYMY (peace, war

JPRS Report, Epidemiology.

DTIC Science & Technology

1989-04-28

intercourse without protection , or through the circulation of previously used drug parapherna- lia. If someone infected in these ways contracts the...OTT A WA CITIZEN, 29 Mar 89] •• ^ DENMARK Homosexuals Infected With HIV Despite Condom Use [Copenhagen BERL1NGSKE TIDENDE, 22 Mar 89] ^ FEDERAL...Research in Country Defended [Oho ^^^f^^^L"^’^’^ 39 Heterosexual Relations Seen Small Risk for AIDS Contag.on [Oslo AFTENPOSTEN, 9 Mar 89] ... 39

Analysis of Turkish Communications Sector and Determination of Critical Success Factors

DTIC Science & Technology

2014-09-01

payments, video streaming, socializing, and online gaming , OTT providers can now easily provide mainstream services such as text messaging and voice...above the regional average as it has sufficient provisions for management of spectra. On the other hand, Ministry can imitate tenders for spectrum...which creates uncertainty about who will initiate tenders . Moreover, the ICTA is free to announce frequency allocation tenders openly and may decide to

The mathematics behind chimera states

NASA Astrophysics Data System (ADS)

Omel’chenko, O. E.

2018-05-01

Chimera states are self-organized spatiotemporal patterns of coexisting coherence and incoherence. We give an overview of the main mathematical methods used in studies of chimera states, focusing on chimera states in spatially extended coupled oscillator systems. We discuss the continuum limit approach to these states, Ott-Antonsen manifold reduction, finite size chimera states, control of chimera states and the influence of system design on the type of chimera state that is observed.

On the palynomorph-based biozones in paleogene strata of rocky mountain basins

USGS Publications Warehouse

Nichols, D.J.

2009-01-01

In a paper published in this journal, and in five previous papers published elsewhere, Lillegraven and McKenna (2008) criticize the research of Nichols and Ott (1978) and Nichols and Flores (2006). They attempt to cast doubt on the validity of the palynomorph-based biozones (the "P- zone" system) applied in strata of Paleocene age throughout the Rocky Mountain region. Their conclusions are without merit.

Bibliography of NRL Publications--1988

DTIC Science & Technology

1990-10-31

2749-2752 Free-Electron Laser , by Schuetz. L.S., Ott, E., and Antonsen, T.M., Physics of Fluids Exact but Computationally Intensive Predictions 0 31...Chemistry. 92:1200-1203, 1988 pp. 212-225 Reactions of Carbon Cluster Ions with Small Picosecond and Nanosecond Laser Photolyses of Hydrocarbons, by...Temperature Superconductors, by Ramnaker, The Study of Cluster Ions by Combined D.E., Turner. N.H.. and Hutson, F.L. ,* Physical Laser /Mass Spectrometry

Human Reliability Prediction System User’s Manual

DTIC Science & Technology

1977-12-01

L Oh.~Nt C.A ICIA I I OMIII ots ?if# IVte AEA AL #4001Im.4,4 up I.-. tte )’fhawA ta *(.qOtte bim.s -vtait hP lSoulp * V1CALS ChET TING 0 IKIVA ofI...on human fectorsin under- sea warfare. Washington, D.C.: Committee on Undersea Warfare, 1949. 8. Blanchard, R.E. Survey of Navy user needs for human

Marketing Analysis and Strategy for a Small Business in the Beekeeping Industry.

DTIC Science & Technology

1980-08-18

segment has opportunities associated with it that may be profitably 2Philip Kotler , "Marketing Management: Analysis, Planning, and Control," Prentice...I I I162 I I BIBLIOGRAPHY IB Abel, Derek and John Hammond. Strategic Market Planning. Englewood Cliffs, N.J.: Prentice- Hall, Inc., 1979. Kotler ... Philip . Marketing Management: Analysis, Planning, and Control. Englewood Cliffs, N.J.: Prentice-Hall, Inc., 1976. Ott, Hyman. Introduction to Statistical

Intramolecular Dynamics: A Study of Molecules at High Levels of Vibrational Excitation.

DTIC Science & Technology

1988-05-27

aareemlent stith the photoa.couxueC rexults.,I4 % obintied t r iii pfii ioaCOI it tic tveaxu retntsx." Si ne thle xhoxs xthat Iii the I ott fi nence...t 0 200 400 ns 6000 between pump and probe pulse for CH3 CHF2 at 660 Pa. Infrared excitation: 10.6 pim P(20) line, 0.5 ns pulse with average fluence

Simultaneously Targeting Myofibroblast Contractility and Extracellular Matrix Cross-Linking as a Therapeutic Concept in Airway Fibrosis

PubMed Central

Lin, Yu-chun; Sung, Yon K.; Jiang, Xinguo; Peters-Golden, Marc; Nicolls, Mark R.

2016-01-01

Fibrosis after solid organ transplantation is considered an irreversible process and remains the major cause of graft dysfunction and death with limited therapies. This remodeling is characterized by aberrant accumulation of contractile myofibroblasts that deposit excessive extracellular matrix (ECM) and increase tissue stiffness. However, studies demonstrate that a stiff ECM, itself, promotes fibroblast-to-myofibroblast differentiation, stimulating further ECM production. This creates a positive feedback loop that perpetuates fibrosis. We hypothesized that simultaneously targeting myofibroblast contractility with relaxin and ECM stiffness with lysyl oxidase inhibitors could break the feedback loop, thereby, reversing established fibrosis. To test this, we used the orthotopic tracheal transplanted (OTT) mouse model, which develops robust fibrotic airway remodeling. Mice with established fibrosis were treated with saline, mono-, or combination therapies. While monotherapies had no effect, combining these agents decreased collagen deposition and promoted re-epithelialization of remodeled airways. Relaxin inhibited myofibroblast differentiation and contraction, in a matrix-stiffness-dependent manner through prostaglandin E2 (PGE2). Furthermore, the effect of combination therapy was lost in PGE2 receptor knockout and PGE2 inhibited OTT mice. This study reveals the important synergistic roles of cellular contractility and tissue stiffness in the maintenance of fibrotic tissue and suggests a new therapeutic principle for fibrosis. PMID:27804215

Military History of the American Revolution. Proceedings of the Military History Symposium (6th) Held at the Air Force Academy, Colo. on 10-11 October 1974,

DTIC Science & Technology

1976-01-01

heartedly planned a coup d’etat to get :he money owed them by Congress.2 6 The Revolution, as; an armed struggle, ended with a whimper. " Hannah Arendt , Ott...HWashington, X, 54-56, 332; David Uriffith to Mrs Hannah Griffith, November 13, 1777, David Griffith Papers. Virginia Historical Society; George Weedon to

Wave Chaos and Coupling to EM Structures

DTIC Science & Technology

2006-07-01

Antonsen, E. Ott and S. Anlage, Aspects of the Scattering and Impedance Properties of Chaotic Microwave Cavities, Acta Physica Polonica A 109, 65...other provision of law, no person shall be subject to a penalty for failing to comply with a collection of information if it does not display a ...currently valid OMB control number. 1. REPORT DATE JUL 2006 2. REPORT TYPE N/ A 3. DATES COVERED - 4. TITLE AND SUBTITLE Wave Chaos and Coupling

Monitoring Species of Concern Using Noninvasive Genetic Sampling and Capture-Recapture Methods

DTIC Science & Technology

2016-06-01

contents be construed as reflecting the official policy or position of the Department of Defense. Reference herein to any specific commercial product...Reserve in Mexico, and is home to more than 400 plant species and over 300 wildlife species. Construction of a border fence along the international...pronghorn mortality, a semi- captive breeding pen was constructed to facilitate pronghorn recovery (Otte 2006). The one- square mile facility is double

U.S. Army Training and Doctrine Command, 1973-1982: A Case Study in Successful Peacetime Military Reform

DTIC Science & Technology

2003-01-01

Member LTC Yvonne Doll, M.S...Tarpley, Cdr, US Army Infantry Center; Donn A. Starry, Cdr, US Army Armor Center; CG LeVan, Cdr, US Army Air Defense Center; William J. Maddox , Cdr, US...Ott, LeVan, Starry, Parfitt, Myer, and Maddox entitled “Field Manuals,” 10 October 1974, in DePuy Papers, MHI. 107DePuy, Letter to General Fred C

Quasi-local conserved charges in Lorenz-diffeomorphism covariant theory of gravity

NASA Astrophysics Data System (ADS)

Adami, H.; Setare, M. R.

2016-04-01

In this paper, using the combined Lorenz-diffeomorphism symmetry, we find a general formula for the quasi-local conserved charge of the covariant gravity theories in a first order formalism of gravity. We simplify the general formula for the Lovelock theory of gravity. Afterwards, we apply the obtained formula on BHT gravity to obtain the energy and angular momentum of the rotating OTT black hole solution in the context of this theory.

Processing, Properties and Morphology of Optical Limiting Silk Membranes

DTIC Science & Technology

2006-02-28

Christopher Brewer, Donald Ott, Polymer, 45 8451 (2004). 2. Electrospun Bombyx mori Gland Silk, S. Putthanarat, R.K. Eby, W. Kataphinan, S. Jones, R...Science, The University of Akron, Akron, OH. 3. American Physical Society (APS) meeting, March 2005, "Electrospun liquid silk from the gland of Bombyx Mori ...provide a good compatible matrix. They have previously demonstrated that GFP molecules can be incorporated into cast membranes of silk from B. mori

Portable Soft X-Ray Laser

DTIC Science & Technology

1992-05-22

ABSTRACT (Maximum 200 worch) A carpact sOtt X-ray laser (SXL) can be designed combining results of Princeton Plasma Physics Laboratory ( PPPL ) and Rutherford...Appleton Laboratory (RAL). At PPPL , gain at 18.2nm was dem- onstrated in a carbon plasma pumped by a low energy laser, with no mag- netic field. The...Physics Laboratory ( PPPL ) and Rutherford Appleton Laboratory (RAL). In the PPPL experiment, gain at a wavelength of 18.2 nm was demonstrated in a

Three or four fractions of 4-5 Gy per week in postoperative high-dose-rate brachytherapy for endometrial carcinoma.

PubMed

Rovirosa, Angeles; Ascaso, Carlos; Sánchez-Reyes, Alberto; Herreros, Antonio; Abellana, Rosa; Pahisa, Jaume; Lejarcegui, Jose Antonio; Biete, Albert

2011-10-01

To evaluate the results of high-dose-rate brachytherapy (HDRBT) using a schedule of three or four fractions per week, when possible, in 89 patients on local control and toxicity in postoperative treatment of endometrial carcinoma. The effect of the overall HDRBT treatment time (OTT) on toxicity was also evaluated. Fédération Internationale de Gynécologie Obstétrique Stage: 24 IB, 45 IC, 4 IIA, 6 IIB, 4 IIIA, 2 IIIB, and 4 IIIC. Radiotherapy: Group 1-67 of 89 patients received external beam irradiation (EBI; 44-50 Gy) plus HDRBT (3 fractions of 4-6 Gy); Group 2-22 of 89 patients received HDRBT alone (6 fractions of 4-5 Gy). OTT: Group 1-HDRBT was completed in a median of 5 days in 32 patients and in >5 days in 35; Group 2-HDRBT was completed in <15 days in 11 patients and in ≥16 days in 11. Toxicity was evaluated using Radiation Therapy Oncology Group scores and the bioequivalent dose (BED) study was performed in vaginal mucosa surface. Statistics included Student's t test, chi-square test, and receiving operator curves. With a mean follow-up of 31 months (range, 6-70), 1 of 89 patients had vaginal relapse. Early toxicity appeared in 8 of 89 (9%) patients and was resolved. Late toxicity appeared in 13/89 (14%): vaginal nine Grade 1, three Grade 2, one Grade 4; bladder two Grade 2; rectal three Grade 1, one Grade 2. No differences were found in relation to OTT in Groups 1 and 2. Mean BED was 88.48 Gy in Group 1 and 165.28 Gy in Group 2. Cases with Grade 2 late vaginal toxicity received >75 Gy after EBI and >165 Gy in Group 2. Three fractions of 4-5 Gy in 3-5 days after EBI or 6 fractions in <15 days in patients receiving HDRBT alone was a safe treatment in relation to toxicity and local control. Vaginal surface BED less than 75 Gy after EBI and less than 160 Gy in HDRBT alone may be safe to avoid G2 toxicity. Copyright © 2011 Elsevier Inc. All rights reserved.

Prognostic Factors and Pattern of Long-Term Recovery with MLC601 (NeuroAiD™) in the Chinese Medicine NeuroAiD Efficacy on Stroke Recovery - Extension Study.

PubMed

Venketasubramanian, Narayanaswamy; Lee, Chun Fan; Young, Sherry H; Tay, San San; Umapathi, Thirugnanam; Lao, Annabelle Y; Gan, Herminigildo H; Baroque Ii, Alejandro C; Navarro, Jose C; Chang, Hui Meng; Advincula, Joel M; Muengtaweepongsa, Sombat; Chan, Bernard P L; Chua, Carlos L; Wijekoon, Nirmala; de Silva, H Asita; Hiyadan, John Harold B; Suwanwela, Nijasri C; Wong, K S Lawrence; Poungvarin, Niphon; Eow, Gaik Bee; Chen, Christopher L H

2017-01-01

The Chinese Medicine NeuroAiD Efficacy on Stroke recovery - Extension (CHIMES-E) study is among the few acute stroke trials with long-term outcome data. We aimed to evaluate the recovery pattern and the influence of prognostic factors on treatment effect of MLC601 over 2 years. The CHIMES-E study evaluated the 2 years outcome of subjects aged ≥18 years with acute ischemic stroke, National Institutes of Health Stroke Scale (NIHSS) score 6-14, pre-stroke modified Rankin Scale (mRS) score ≤1 included in a multicenter, randomized, double-blind, placebo-controlled trial of MLC601 for 3 months. Standard stroke care and rehabilitation were allowed during follow-up with mRS score being assessed in-person at month (M) 3 and by telephone at M1, M6, M12, M18 and M24. Data from 880 subjects were analyzed. There was no difference in baseline characteristics between treatment groups. The proportion of subjects with mRS score 0-1 increased over time in favor of MLC601 most notably from M3 to M6, thereafter remaining stable up to M24, while the proportion deteriorating to mRS score ≥2 remained low at all time points. Older age (p < 0.01), female sex (p = 0.06), higher baseline NIHSS score (p < 0.01) and longer onset to treatment time (OTT; p < 0.01) were found to be predictors of poorer outcome at M3. Greater treatment effect, with more subjects improving on MLC601 than placebo, was seen among subjects with 2 or more prognostic factors (OR 1.65 at M3, 1.78 at M6, 1.90 at M12, 1.65 at M18, 1.39 at M24), especially in subjects with more severe stroke or longer OTT. The sustained benefits of MLC601 over 2 years were due to more subjects improving to functional independence at M6 and beyond compared to placebo. Selection of subjects with poorer prognosis, particularly those with more severe NIHSS score and longer OTT delay, as well as a long follow-up period, may improve the power of future trials investigating the treatment effect of neuroprotective or neurorestorative therapies. © 2016 The Author(s) Published by S. Karger AG, Basel.

Neutron Diffraction Studies of Some Rare Earth-Transition Metal Deuterides.

DTIC Science & Technology

1986-05-01

RD-A168 M NEUTRON DIFFRACTION STUDIES OF SONE RARE EARTH-TRANSITION METAL DEUTERIDES(U) MISSOURI UNIV-ROLLR MATERIALS RESEARCH CENTER N J JAMES MY 86...REPORT William J. James OTtO -il May 1986 ZLECTEJU U. S. Army Research Office DAAG29-83-K-01 59 ".;’ Graduate Center for Materials Research ...9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT, PROJECT. TASK AREA & WORK UNIT NUMBERS 2* Graduate Center for Materials Research

Evaluation of the Immunologic Impact of RAF Inhibitors to Guide Optimal Combination of RAF Inhibitors and Immunotherapy for the Treatment of Advanced Melanoma

DTIC Science & Technology

2013-10-01

Association  for  Cancer  Research  2012.   4.   Koya  RC,  Mok  S,  Otte  N,  et  al.  BRAF  inhibitor   vemurafenib ...Hodi  FS,  Callahan  M,  Konto  C,  Wolchok  J.  Hepatotoxicity  with  combination   of   vemurafenib  and  ipilimumab

A new species of subgenus Eulandrevus Gorochov, 1988 (Orthoptera: Gryllidae: Landrevinae) from China.

PubMed

Liu, Yang; He, Zhuqing; Ma, Libin

2015-09-11

Duolandrevus crickets are brown, smooth, shiny and bear reduced tegmina. They are forest species and have an equatorial distribution. Only the subgenus Eulandrevus of this genus, containing three species, has been recorded from China. Here, an additional species is described, recently discovered on Hainan Island, China. This species is similar to Duolandrevus (Eulandrevus) hongkongae Otte, 1988, but differs in body size and details of the elytra and genitalia. The description and illustrations of the new species Duolandrevus hainanensis are provided.

Delta 181 Sensor Module Command Center

DTIC Science & Technology

1989-09-01

Irot a rtiission perspectixc, operariort of lIte coltiiand center \\\\as, tight Iv coupled to corntrol cot11IrplX Operarll oIr 1lrefrc. bef’ore \\N e...8217, plantnin, It liTe latest alerts, accessed b\\ tile (olosnk cornt- putter displayv program, ss crc placedi ott all telretr\\ data displa\\ 5. 3.3.3 1health...ePackeizer Command echo Detected ,, ,/’ vRF Gomr, nad Center AF! CN Joophbick po~nts rpback Aoonops I Test loopback pairt Fig. 3-3 Major loopback

Environmental Assessment for Construction and Repair of Fuel Storage and Offloading Facilities at Kirtland Air Force Base

DTIC Science & Technology

2005-09-01

G Ot-T GOO) D. BRENT WILSON, P.E. Base Civil Engineer Kirtland Air Force Base Kirtland AFB Fuel Storage and Ofjloading Facilities Construction...September 2005 A-1 3 77 MSG/CEVQ DEPARTMENT OF THE AIR FORCE 3 77th Civil Engineer Division (AFMC) 2050 Wyoming Blvd SE, Suite 120 Kirtland AFB NM...FINAL FINDING OF NO SIGNIFICANT IMPACT FOR THE FOR CONSTRUCTION AND REP AIR OF FUEL STORAGE AND OFFLOADING FACILITIES AT KIRTLAND AIR FORCE

Creep and Fatigue Interaction in the PWA 1484 Single Crystal Nickel-Base Alloy (Preprint)

DTIC Science & Technology

2011-07-01

work by Zhang et al . has shown that during the early part of fatigue cycling dislocations are formed primarily in the γ matrix with the number of...dislocations increasing with the number of applied cycles [11]. Ott and Mughrabi showed that during fatigue of single crystal nickel base superalloys... al . and their research determined that the fatigue behavior of PWA1484 could be well represented by a Walker type fatigue model that also included

Radiometric Measurements by the MIDAS III System at Key West. Volume I. Cloud Backgrounds.

DTIC Science & Technology

1979-09-01

13 13.3 System Relative Spectral Response - Filter No. 2 5(4.4-4.77 pim ) ............................................. 14 3.4 System Relative Spectral...Response - Filter No. 5 (3.8-4.2 pim ) .............................................. 15 3.5 System Relative Spectral Response - Filter No. 6 (3.4-4.3...5 dat a was recorded dirtxet l ott t he recordinig osc ml logrtt1 Witereis tilt- 8-13 data was recorded on t tiet I ape, recorders i xst itd laxter p

Littoral Combat Ship (LCS) Mission Packages: Determining the Best Mix

DTIC Science & Technology

2008-03-01

to thank CAPT Doug Otte , USN, CDR Doug Burton, USN, Colonel Ed Lesnowicz, USMC (Ret.), Lloyd Brown, LCDR Scott Hattway, USN, and LT John Baggett...clear it of any surface threats. Upon commencement, SUW LCS are following assigned PIM into the channel with an embarked MH-60R airborne. Upon enemy... PIM . Since LCS is a focused mission platform, a SUW LCS will not pursue anything other than a surface threat (i.e. it will not pursue, and cannot

Fingerprints in the Great Basin: The Nellis Air Force Base Regional Obsidian Sourcing Study

DTIC Science & Technology

2005-01-01

obsidian-bearing alluvial deposits de - parts of the magma chamber are tapped, con- rived from the regionally extensive rhyolite centrations of Ba increase...gfold wing de scripti ons of Osi u ott hneVolcanic nou st Kawic rakinge the Be Ceuntern, Oak Spring Butte, South Kawich RangeGopwr rpedbten1. n Devil...2004 field season. These de - NTTR-NTS boundary in Nye County, Nevada. scriptions provide information about geologic age The Grouse Canyon Caldera lies

Survival of the lichen model system Circinaria gyrosa before flight to the ISS (EXPOSE R2 mission)

NASA Astrophysics Data System (ADS)

De la Torre Noetzel, Rosa

Abstract Space Verification Tests (SVT) are necessary for selection of the most promising biological organisms for flight experiments in Low Earth Orbit or other space destinations: Simulation of sample assembly, exposure to expected space parameters and sample disassembly are significantly advanced by such tests, will be performed with this tests, allowing post-analysis of the exposed biological material and thus a deeper understanding of the individual and synergistic effects of space. In this work we present the results obtained with the lichen species Circinaria gyrosa after the SVT 2 run-2 tests concerning the EXPOSE-R2 Mission Preflight Test Program, performed at the planetary and space simulation facilities at DLR (Deutsches Zentrum für Luft- und Raumfahrt, Cologne, Germany) [1], from October 2013 to January 2014. This vagrant lichen species was collected at the steppic highlands of Central Spain and defined as “astrobiological model system” due to previous test at space missions (BIOPAN-6, Foton M-3) [2, 3], Therefore, C. gyrosa is part of the BIOMEX experiment (Biology and Mars Experiment, ESA) [4] which will be exposed from July 2014 to January 2016 on board of EXPOSE R2 on the International Space Station. C. gyrosa was exposed at DLR to simulated space- and Mars parameters: a) space vacuum 10-5 Pa, space UV-radiation (200-400 nm, fluence of 12 months mission = 5 x 105 kJm-2) and temperature fluctuations (-25 ºC to 10 ºC); b); Mars Simulated CO2 atmosphere, Mars pressure of 103 Pa, Mars UV-radiation (200-400 nm), and temperature fluctuations (-25 ºC to 10 ºC). In line with the lichen's well studied adaptations to harsh environmental conditions [5, 6] we observed a high recovery- and resistance capacity of C. gyrosa which was demonstrated after a 72 hours re-activation process of in the UV-Radiation and Bioclimatology Laboratories of INTA (Atmospheric Research and Instrumentation, Dept. Earth Observation). These results confirm the high survival potential to space and Mars conditions, contributing to our understanding of extremotolerance and the Lithopanspermia hypothesis [7]. References [1] Rabbow, E., und Rettberg, Petra und Barczyk, Simon und Bohmeier, Maria und Parpart, André und Panitz, Corinna und Horneck, Gerda und von Heise-Rotenburg, Ralf und Hoppenbrouwers, Tom und Willnecker, Rainer und Baglioni, Pietro und Demets, René und Dettmann, Jan und Reitz, Guenther (2012) EXPOSE-E: An ESA Astrobiology Mission 1.5 Years in Space. Astrobiology, 12 (5), Seiten 374-386. Mary Ann Liebert, Inc.. DOI: 10.1089/ast.2011.0760. [2] De la Torre, R. L.G. Sancho, G. Horneck, A.de los Ríos, J. Wierzchos, K. Olsson-Francis, C.S. Cockell, Rettberg P., T. Berger, J.P. de Vera, S. Ott, J. Martinez Frías, P.Gonzalez Melendi M.M. Lucas, M. Reina, A. Pintado, R.Demets. Survival of lichens and bacteria exposed to outer space conditions. Results of the Lithopanspermia experiments. Icarus, doi:10.1016/j.icarus.2010.03.010 (2010). [3] Sanchez, F.J., E. Mateo-Martí, J. Raggio, J. Meessen, J. Martinez-Frias, L. Gª Sancho, S. Ott and R. de la Torre. The resistance of the lichen Circinaria gyrosa (nom. provis.) towards simulated Mars conditions - a model test for the survival capacity of an eukaryotic extremophyle. Planetary and Space Science 72, 102-110 (2012). [4] de Vera JP and the BIOMEX-Team (2012) Supporting Mars exploration: BIOMEX in Low Earth Orbit and further astrobiological studies on the Moon using Raman and PanCam technology. Planetary and Space Science, 74 (1), Seiten 103-110. Elsevier. DOI:10.1016/j.pss.2012.06.010. [5] Meeßen J, Sánchez FJ, Brandt A, Balzer EM, de la Torre R, Sancho LG, de Vera JP, Ott S (2013) Extremotolerance and resistance of lichens: Comparative studies on five species used in astrobiological research I. Morphological and anatomical characteristics. Origins of Life and Evolution of Biospheres 43 (3): 283-303 [6] Meeßen J, Sánchez FJ, Sadowsky A, de Vera JP, de la Torre R, Ott S (2013) Extremotolerance and resistance of lichens: Comparative studies on five lichen species used in astrobiological research II. Secondary lichen compounds. Origins of Life and Evolution of Biospheres, online-first publication, doi: 10.1007/s11084-013-9348-z [7] Mileikowsky C, Cucinotta F, Wilson JW, Gladman B, Horneck G, Lindegren G, Melosh J, Rickman H, Valtonen M, Zheng JQ (2000) Natural transfer of viable microbes in space, Part 1: From Mars to Earth and Earth to Mars. Icarus 145, 391-427

Two months of disdrometer data in the Paris area

NASA Astrophysics Data System (ADS)

Gires, Auguste; Tchiguirinskaia, Ioulia; Schertzer, Daniel

2018-05-01

The Hydrology, Meteorology, and Complexity laboratory of École des Ponts ParisTech (hmco.enpc.fr) has made a data set of optical disdrometer measurements available that come from a campaign involving three collocated devices from two different manufacturers, relying on different underlying technologies (one Campbell Scientific PWS100 and two OTT Parsivel2 instruments). The campaign took place in January-February 2016 in the Paris area (France). Disdrometers provide access to information on the size and velocity of drops falling through the sampling area of the devices of roughly a few tens of cm2. It enables the drop size distribution to be estimated and rainfall microphysics, kinetic energy, or radar quantities, for example, to be studied further. Raw data, i.e. basically a matrix containing a number of drops according to classes of size and velocity, along with more aggregated ones, such as the rain rate or drop size distribution with filtering, are available. Link to the data set: https://zenodo.org/record/1240168 (DOI: https://doi.org/10.5281/zenodo.1240168).

Canadian community pharmacists' use of digital health technologies in practice.

PubMed

Leung, Valerie; Tharmalingam, Sukirtha; Cooper, Janet; Charlebois, Maureen

2016-01-01

In 2010, a pan-Canadian study on the current state and benefits of provincial drug information systems (DIS) found that substantial benefits were being realized and that pharmacists perceived DIS to be a valuable tool in the evolving models of pharmacy practice. To understand changes in digital health and the impact on practice since that time, a survey of community pharmacists in Canada was conducted. In 2014, Canada Health Infoway (Infoway) and the Canadian Pharmacists Association (CPhA) invited community pharmacists to participate in a Web-based survey to understand their use and perceived benefits of digital health in practice. The survey was open from April 15 to May 12, 2014. Of the 447 survey responses, almost all used some form of digital health in practice. Those with access to DIS and provincial laboratory information systems (LIS) reported increased productivity and better quality of care. Those without access to these systems would overwhelmingly like access. There have been significant advances in digital health and community pharmacy practice over the past several years. In addition to digital health benefits in the areas of productivity and quality of care, pharmacists are also experiencing substantial benefits in areas related to recently expanded scope of practice activities such as ordering lab tests. Community pharmacists frequently use digital health in practice and recognize the benefits of these technologies. Digital health is, and will continue to be, a key enabler for practice transformation and improved quality of care. Can Pharm J (Ott) 2016;149:xx-xx.

A one-to-one telestroke network: the first Italian study of a web-based telemedicine system for thrombolysis delivery and patient monitoring.

PubMed

Nardetto, Lucia; Dario, Claudio; Tonello, Simone; Brunelli, Marta Carla; Lisiero, Manola; Carraro, Maria Grazia; Saccavini, Claudio; Scannapieco, Gianluigi; Giometto, Bruno

2016-05-01

Over 10 years after European approval, thrombolysis is still limited by a restricted time window and non-optimal territorial coverage. Implementation of telestroke can give a growing number of patients access to treatment. We hereby present the first Italian telemedicine study applied to both the acute and the monitoring phase of stroke care. From January 2011 to December 2013, we tested a web-based, drip, and treat interaction model, connecting the cerebrovascular specialist of one hub center to the Emergency Department of a Spoke center. We then compared thrombolysis delivered using the telestroke model with thrombolysis provided at the Hub Stroke Unit at the time when the telemedicine program was activated. Telethrombolysis data were then compared with data from the two main international telestroke projects (TEMPiS and REACH), and other European telestroke studies performed at the time of writing. We collected a total of 131 thrombolysis procedures (25 telethrombolysis and 106 thrombolysis patients at the Stroke Unit). Statistical analysis with the t test yielded no statistically significant differences between the two populations in door-to-scan, door-to-needle (DTN), and onset-to-treatment times (OTT). Our OTT and DTN pathway times were longer than the TEMPiS and REACH studies but comparable with other European telemedicine trials, despite different models of interaction and number of centers. Our study in a northeastern province of Italy confirms the potential of applying telemedicine to a cerebrovascular pathology.

New taxa and notes on crickets of the subfamily Landrevinae (Orthoptera: Gryllidae) from Brunei Darussalam, Borneo.

PubMed

Tan, Ming Kai; Wahab, Rodzay Bin Haji Abdul

2017-12-19

New taxa from the subfamily Landrevinae (Orthoptera: Gryllidae) are expected despite recent work on its taxonomy. Here, two more new species from Brunei Darussalam, Borneo are described: Duolandrevus (Eulandrevus) kawataredoki sp. nov. and Endodrelanva nympha sp. nov. The male calling song of D. (E.) kawataredoki sp. nov. is also described. We report the occurrence of a Duolandrevus (Bejorama) from Brunei close to (nr.) luzonensis Otte, 1988. We also document from Brunei a case of parasitic wasp from the genus Liris (Hymenoptera: Crabronidae: Larrini) hunting a Landrevinae.

Numerical and analytical investigation of the chimera state excitation conditions in the Kuramoto-Sakaguchi oscillator network

NASA Astrophysics Data System (ADS)

Frolov, Nikita S.; Goremyko, Mikhail V.; Makarov, Vladimir V.; Maksimenko, Vladimir A.; Hramov, Alexander E.

2017-03-01

In this paper we study the conditions of chimera states excitation in ensemble of non-locally coupled Kuramoto-Sakaguchi (KS) oscillators. In the framework of current research we analyze the dynamics of the homogeneous network containing identical oscillators. We show the chimera state formation process is sensitive to the parameters of coupling kernel and to the KS network initial state. To perform the analysis we have used the Ott-Antonsen (OA) ansatz to consider the behavior of infinitely large KS network.

A Review of the Processes that Control Snow Friction

DTIC Science & Technology

1992-04-01

initeracetion its well ats llteltw.’Cl change . or lubrilcation. W~itll these lithin filmns. I~vatls et il]. (I 976j suZ,-custed u~,i~u= ’~p(19) tihat...pesol slx. Ut1m ,Itll[s used. It is know\\it that electrical clmatees can ,tise floort that1 ititetac \\txiitli "’. -N: those thatsill otte xII ýClll d i... change in angle greatly incr-ases C "iri,; on snowv as contmsti ng of three componentsM wriose tire drag oai trie sl idc. relative significance

Wrought Stainless Steel Fasteners for Civil Works Applications.

DTIC Science & Technology

1982-03-01

Library Europe 09757 Fort Devens 01433 Huntsville 35807 Fort Drum 13604 ETL, AIT: Library 22080 Lower Mississippi Valley 39180 Fort Hood 76544 Middle...general C ). It cati be nitrided anid shows a dimnensiotnal cont rac - fabricating characteristics of’ 17-4 P11 SS are sitnilat tion ott heat t reatmnt tiup...CCP ATTN: EAE-ID 96224 Fort Lesley J. nesir euJn AIIN: OALM CH AITN: EAFE-41 9b/Ud Fort Myer eZZ1 AIIM. UAE-Cat ATTN: tAFE-H 9b271 ATTN, UAA-CW4M

Infrared Measurement Variability Analysis.

DTIC Science & Technology

1980-09-01

collecting optics of the measurement system. The first equation for tile blackbody experiment has the form 4.0 pim _ Ae W ,T) r(X,D) 3.5 pm - 4.0 pm JrD2 f3.5...potential for noise reduction by identifying and reducing contributing system effects. The measurement variance ott . of an infinite population of possible...irradiance can be written 4.0 pm I r()A A+ A ) 2 4.0 X C1(, = W(XT + AT)d 3.5 pim I since c + Af =2 r +Ar I Using the two expressions juSt devclopCd

Investigation of Methods to Eliminate Voltage Delay in Li/SOCl2 Cells.

DTIC Science & Technology

1980-05-01

of storage at 550C the surface was completely covered with cubic crystals averaging about 8 pim on an edge (Figure 24). The lithium surface stored at...completely covered with cubic crystals, showing no smooth undercoating at all (Figure 25). The average crystal diameter was approximately 3.3 pim , with a...used. ithi timl acgu ire0d A Ci yst al I me surt ace, oil dr n torage at elevated temlper aI Ite t. T[he out lace, showed ch[ ott ine by EPAC except

Lateral Translation of Explosion Crater Ejecta: A Working Model Based Upon Pellet Experiments

DTIC Science & Technology

1975-08-19

OMNEIS IOOCT7?I3 I6LR$I4ALE -aUS6IfniCrkFVICLS INCH# CRATER **OIUSIOC).1.661 MEllERS PIM TttE 996 09 Ror SWt v 7*¶16I’ ff3 ---- PREUICT EtLLEI RA.F...229 Set1? -.4711’ 1.q926 2.r,392 .40497 .35 .40!7, -. 19620 I.?qa ",3645 .76 ____ .11 .570 -. P9979 t.r9t P.0,16. .M247- .457 W604 -.?? Ott .044

Technical Considerations for Improvement of USAF Operational Training, Testing and Evaluation (OTT and E)

DTIC Science & Technology

1975-06-30

Needs 24 3-4 Needs 25 3-5 EW Scoring Considerations 28 3-6 Risk vs Benefit - Voluntary & 30 Involuntary Exposure 3-7 Mapping of Dollar Loss to the Air...method? Of this new jammer? Or this new tactic? Or this new airplane?" Can all be answer3d by showing how aircraft losses were lessened, while...30 approach does not present a cost basis to determine the dollar worth of safety improvements. Figure 3-7 shows the average dollar loss of

Evaluation of the Ott Hydromet Qliner for measuring discharge in laboratory and field conditions

USGS Publications Warehouse

McVay, Jason C.

2015-01-01

The U.S. Geological Survey, in collaboration with the University of Iowa IIHR – Hydroscience and Engineering, evaluated the use of the Ott Hydromet Qliner using laboratory flume tests along with field validation tests. Analysis of the flume testing indicates the velocities measured by the Qliner at a 40-second exposure time results in higher dispersion of velocities from the mean velocity of data collected with a 5-minute exposure time. The percent data spread from the mean of a 100-minute mean of Qliner velocities for a 40-second exposure time averaged 16.6 percent for the entire vertical, and a 5-minute mean produced a 6.2 percent data spread from the 100-minute mean. This 16.6 percent variation in measured velocity would result in a 3.32 percent variation in computed discharge assuming 25 verticals while averaging 4 bins in each vertical. The flume testing also provided results that indicate the blanking distance of 0.20 meters is acceptable when using beams 1 and 2, however beam 3 is negatively biased near the transducer and the 0.20-meter blanking distance is not sufficient. Field testing included comparing the measured discharge by the Qliner to the discharge measured by a Price AA mechanical current meter and a Teledyne RDI Rio Grande 1200 kilohertz acoustic Doppler current profiler. The field tests indicated a difference between the discharges measured with the Qliner and the field reference discharge between -14.0 and 8.0 percent; however the average percent difference for all 22 field comparisons was 0.22, which was not statistically significant.

Word Criticality Analysis. MOS: 67N. Skill Levels 1 & 2

DTIC Science & Technology

1981-09-01

12 1 , lat 0.. 71N 4 1 s,1 󈧅 119 *I .!Ill4 r ITr L34 U., p I*. 1, r-*44,1I6 C. I ", il. TD %T i - 96’ !04- 2,1 -i: l st a64 1104 121! tio 2...14 1’.1 !$04 4:4 11.1* :74 :’~ ~4 te 4 , 4?. 4.. 7 ., !:j-q1 , **)4 1Q3 *2 .1 .~ 4134 . 1.,’ 4- 1 41st -74 Ott. 󈧒 *4 . ,4 4,7Y t 1 46520 n190 37.1

A new species of the genus Duolandrevus (Orthoptera: Gryllidae: Landrevinae) from China.

PubMed

Ma, Libin; Gorochov, Andrej V; Zhang, Yalin

2015-05-27

A bark cricket genus Duolandrevus Kirby, 1906 is discussed here. These species are brownish with depressed bodies, with reduced elytra, lack hind wings and live in the bark of dead trees or branches. Duolandrevus are distributed from the south of China and Japan to the Philippines, the Malay Archipelago and New Guinea. Only one species, Duolandrevus hongkongae Otte, 1988, was recorded in China. Here, one additional species, Duolandrevus (Eulandrevus) unguiculatus sp. nov. is described from Southern China. Its description and illustrations and the key to the subgenera of Duolandrevus worldwide are given.

Attenuation of Electromagnetic Radiation by Haze, Fog, Clouds, and Rain

DTIC Science & Technology

1975-04-01

transmission data of Gebbie etal,(3 Gibbons (27) suggests that ai = 0.7 in the wavelength range from 0.61 to 11.48 pim regardless of the meteorological...attenuation at 10 Um becomes 10 to 100 times smaller than at 0.5 jim. It can be also observed that the 8 to 12 pm band is preferable to the 3 to 5 pim ...Water Aerosols and Fog-," Arl. ¢ Ott ., Vol. 9, 1970, pp. 2000-2006. 33. Gebbie, If. A., ot al., "Atmospheric Transmission in the 1 to 14P Region," Pro

The role of fire in the Central European lowlands during the Holocene: what we know so far

NASA Astrophysics Data System (ADS)

Dietze, Elisabeth; Theuerkauf, Martin; Słowiński, Michał; Brauer, Achim

2017-04-01

The modern landscape of the Central European lowlands results from the complex interaction between its geological and geomorphological configuration that developed during and after the last glaciation as well as its Holocene vegetation history, climate evolution and human activity. Although also fire is known to play a fundamental role in many ecosystems of the world and to be one of the major tools for anthropogenic land cover change, Holocene paleofire history has only marginally been studied in the area of the Central European lowlands so far. Here, we will present the first attempt to establish a Holocene fire synthesis for the Central European lowlands. In a first step, we aim to reconstruct the regional Holocene fire history by comparing available sedimentary charcoal records from lakes and peatlands of northern Germany, northern Poland and the Baltic countries. We will present the current knowledge on the role of fire during different time windows such as the Neolithic period, the Medieval time and the onset of industrialization. In addition, we will discuss the interaction between fire, human activity, vegetation and climate change during the last 250 years in more detail using high-resolution records of sedimentary charcoal and the fire biomarkers levoglucosan, mannosan and galactosan from the annually laminated lake sediments of Lake Czechowskie, northern Poland. Teams: CEL synthesis - A. Feurdean, M. Obremska, M. Lamentowicz, K. Marcisz, W. Dörfler, I. Feeser, N. Dräger, F. Ott, T. Giesecke, S. Jahns, L. Shumilovskikh, S. Veski, M. Wieckowska-Lüth, J. Wiethold; Czechowskie fire biomarkers - E.C. Hopmans, L.T. Schreuder, M. Obremska, A. Pieńczewska, O. Blarquez, F. Ott, D. Brykala, S. Schouten

Automatic Relocation of Ground Control Points in Landsat Imagery

DTIC Science & Technology

1981-06-01

This progras mtes use of a method of relocating in.jviiU.u1 S-p. this beini, done by Ott s~brosotir.. UXICCPF klocali-t gzp ). which is des.:ritrJ in t...dAil in se zt ’n ’. Erk t falJmit sec:tikrns dtscr-"be thv all gzps in ar. image ar.e iocate~.ý 3.2 CrýUnd c.Yntr,ýl pinat’cpu The tasýk or t~~IS...using the purpose-written progrn Ifl.CMI!P IX. The prc-blea cf rwltccating gzps is madle nic-h easier than the general pattern iecugnitior pmt.aleu

The Institute for Mathematics and its Applications. Volume 68, Flow Control,

DTIC Science & Technology

1994-01-01

agreenient. is also demonstr,.ted at a greater speed ratio a = 3.25. A detailed discussion of the accuracy of thc numerical sq- heme can be found in f8]. 4.1...to bound- ary variations. "u snake this expression for the gradient well- definted , one must show that this shape derivative exists. One would like to...q C2 and j’(r)v= (4.4) /S (u)- u. ÷ •v6 - p it,,,2+ •(-)V"dr rIr Ott 2 wi’frc 4 and 0, are definted es abover. ADA294785 338 THOMAS SYOBODNY 5

Strength and fatigue of NT551 silicon nitride and NT551 diesel exhaust valves

DOE Office of Scientific and Technical Information (OSTI.GOV)

Andrews, M.J.; Werezczak, A.A.; Kirkland, T.P.

2000-02-01

The content of this report is excerpted from Mark Andrew's Ph.D. Thesis (Andrews, 1999), which was funded by a DOE/OTT High Temperature Materials Laboratory Graduate Fellowship. It involves the characterization of NT551 and valves fabricated with it. The motivations behind using silicon nitride (Si{sub 3}N{sub 4}) as an exhaust valve for a diesel engine are presented in this section. There are several economic factors that have encouraged the design and implementation of ceramic components for internal combustion (IC) engines. The reasons for selecting the diesel engine valve for this are also presented.

Effects of Low-Dose Total-Body Irradiation on Canine Bone Marrow Function and Canine Lymphoma

DTIC Science & Technology

1981-11-01

SCIENTIFIC REPORT Effects of low-dose total-body irradiation on canine bone marrow function and canine lymphoma cc ca D. E. Cowal! 7. J. MacVittie G... CANINE BONE MARROW FUNCTION AND CANINE LYMPHOMA 6. PERFORMING O1G. REPORT NUMBER 7. AUTHO1R(s) 8. CONTRACT OR GRANT NUMBER(s) Dt E. Cowall*, T. J...ott it e r .f00 !(1414011V byt block tumbv,) canine , I’M, bone marrow, GM-CFC 20 A US TR AC y t (𔃺t 104#0 00 ,r ,. @#PS#0 It Ml 0 le~ 9 ncj0 dd0 19

Defense Manpower Commission Staff Studies and Supporting Papers. Volume 2. The Total Force and Its Manpower Requirements Including Overviews of Each Service

DTIC Science & Technology

1976-05-01

J^^’.Si*!** \\ ir..’’T^-.’-T*TSfn titoa i iMBi’M, OTTŕ" ,^~" fraCk k^«^;-<^»J,..;^.a,L.^t»^^ri^fc ft WBMyLmH’.’JW*^Hi,.J , Jl,l|llliln|Kli|Pffl...also develop a means to inspect tube internals to insure they are clean 11. Develop a deep tank, high volume, high head hydraulic driven pump to...and procedures that have been implemented at this Command and havs en- hanced productivity are: - Power floor cleaners Pneumatic/ hydraulic ram tire

Preliminary Common Module Design Handbook.

DTIC Science & Technology

1976-04-02

oat* circuit« it • canttant currant tourca <Q’’ With «a rosso « current «rive. V threuah 05 era turna* off thus thuttine *e*n the...ply» heat input renf’*9 fro» toro *h -r IS •mute« aa«iau» to 77* Kelvin »tertiea to 0 * «Ott at cold fieaer taaeeretwre of...trie «c»l»t ond OOjuOt for • toro Ml Ccr«ful|y pour llowitf nitrooon HU into tho d»t»ctor/o«M»r «wdu’-p I to». Con- tlnwa

Development of a Computer Model for Scattering of Electromagnetic Waves by a Turbulent Wake

DTIC Science & Technology

1976-10-01

01. W WO V m PiM NNN 0 0P o NI’ggo*.Ne~~~ 40 .INWN 4 I-.oAg , i- £ oc..eec a, *e ggg0eg.c e C30c O Ooa. Coo e r.g..00000mo.. k w 30 N on. N M...0 y 6 . N -.1, -0𔃺 64 6404 i 09000 aI ~III IL. W I 4 0 0, 1W0 I 0~ I 4 S- qw~ ____________’ .9 us, 4K C*I: 4W 0 fo # l C w 6 0o m. Ott ilfl,,0 0

Dynamics of a population of oscillatory and excitable elements.

PubMed

O'Keeffe, Kevin P; Strogatz, Steven H

2016-06-01

We analyze a variant of a model proposed by Kuramoto, Shinomoto, and Sakaguchi for a large population of coupled oscillatory and excitable elements. Using the Ott-Antonsen ansatz, we reduce the behavior of the population to a two-dimensional dynamical system with three parameters. We present the stability diagram and calculate several of its bifurcation curves analytically, for both excitatory and inhibitory coupling. Our main result is that when the coupling function is broad, the system can display bistability between steady states of constant high and low activity, whereas when the coupling function is narrow and inhibitory, one of the states in the bistable regime can show persistent pulsations in activity.

Penetrator Impact Studies of Soil/Concrete

DTIC Science & Technology

1977-11-01

JATINS OF MOTION OL1 ,O4 T01 oll , .’APOIMO ,ci • • di 010@m •’e - Cal ted X .Expa tal . . .... . .... . ... . • - -- ---- 007M6 iti (1 /7 x 01" IME...F4W*3,# TimVerO Deth f Pat~ton, m Sot N. 7 (C N.41 w - - - - -- . -# rTCEM~nyNM4c VCHICLI C@JltIs or "OttON 5.0 VEPINIO4 ?Oil I - Cale ted X Exper...os04𔃾--- ,oeiJ rig~W 2. i TIMu Vemsis U)pth of POUetwati~9Or Sho t, X. -󈨘. (Cp ww4.) so, TERRADYNAMIC VVHICLE f(kTI" Or MOTIO OL ESO Tl a -- Calcul ted

Multiple Magma Batches Recorded in Tephra Deposits from the Toba Complex, Sumatra.

NASA Astrophysics Data System (ADS)

Pearce, N. J. G.; Westgate, J.; Gatti, E.

2015-12-01

The Toba Caldera Complex is the largest Quaternary caldera on Earth, and has generated three voluminous and compositionally similar rhyolitic tuffs, viz. the Oldest (OTT, 800 ka), Middle (MTT, ~500 ka) and Youngest Toba Tuffs (YTT, 75 ka). These tephra deposits are widespread across Indonesia, Malaysia, South China Sea, Sea of Bengal, India and Indian Ocean and provide useful stratigraphic markers in oceanic, lacustrine and terrestrial environments. Single shard trace element analysis of these deposits reveals the changing availability of different batches of magma through time, with Sr, Ba and Y contents defining 5 discrete magma populations in YTT, 4 populations in MTT and only a single, low Ba population in OTT. Within an individual eruption these populations are clearly distinct, but between eruptions (e.g. MTT and YTT) some of these populations overlap while others do not, indicating both the longevity (and/or continuous supply of fresh material) and evolution of these magma batches in the Toba Complex. Major element compositions of the different groups show equilibration at different pressures (based on Q'-Ab'-Or'), with the equilibration of low Ba populations at ~160 MPa, increasing to depths of ~210 MPa for the highest Ba population. The proportions of different populations of glass in distal YTT shows that relatively little of the high Ba population makes it into the distal record across India, and that this population appears to be over-represented in the proximal free glass and pumice from the caldera walls. This data may shed light on magma availability and tephra dispersal during the YTT eruption. Similarly, the glass composition of individual pumices from proximal deposits record regional, compositional and temporal differences in the erupted products. These show, for example, the apparent mingling of some of the magma batches and also that the high Ba population appears early (i.e. stratigraphically lower) in the northern caldera wall.

Relationship between radiation treatment time and overall survival after induction chemotherapy for locally advanced head-and-neck carcinoma: a subset analysis of TAX 324.

PubMed

Sher, David J; Posner, Marshall R; Tishler, Roy B; Sarlis, Nicholas J; Haddad, Robert I; Holupka, Edward J; Devlin, Phillip M

2011-12-01

To analyze the relationship between overall survival (OS) and radiation treatment time (RTT) and overall treatment time (OTT) in a well-described sequential therapy paradigm for locally advanced head-and-neck carcinoma (LAHNC). TAX 324 is a Phase III study comparing TPF (docetaxel, cisplatin, and fluorouracil) with PF (cisplatin and fluorouracil) induction chemotherapy (IC) in LAHNC patients; both arms were followed by carboplatin-based chemoradiotherapy (CRT). Prospective radiotherapy quality assurance was performed. This analysis includes all patients who received three cycles of IC and a radiation dose of ≥70 Gy. Radiotherapy treatment time was analyzed as binary (≤8 weeks vs. longer) and continuous (number of days beyond 8 weeks) functions. The primary analysis assessed the relationship between RTT, OTT, and OS, and the secondary analysis explored the association between treatment times and locoregional recurrence (LRR). A total of 333 (of 501) TAX 324 patients met the criteria for inclusion in this analysis. There were no significant differences between the treatment arms in baseline or treatment characteristics. On multivariable analysis, PF IC, World Health Organization performance status of 1, non-oropharynx site, T3/4 stage, N3 status, and prolonged RTT (hazard ratio 1.63, p=0.006) were associated with significantly inferior survival. Performance status, T3/4 disease, and prolonged RTT (odds ratio 1.68, p=0.047) were independently and negatively related to LRR on multivariable analysis, whereas PF was not. Overall treatment time was not independently associated with either OS or LRR. In this secondary analysis of the TAX 324 trial, TPF IC remains superior to PF IC after controlling for radiotherapy delivery time. Even with optimal IC and concurrent chemotherapy, a non-prolonged RTT is a crucial determinant of treatment success. Appropriate delivery of radiotherapy after IC remains essential for optimizing OS in LAHNC. Copyright © 2011 Elsevier Inc. All rights reserved.

Relationship Between Radiation Treatment Time and Overall Survival After Induction Chemotherapy for Locally Advanced Head-and-Neck Carcinoma: A Subset Analysis of TAX 324

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sher, David J., E-mail: dsher@partners.org; Posner, Marshall R.; Tishler, Roy B.

2011-12-01

Purpose: To analyze the relationship between overall survival (OS) and radiation treatment time (RTT) and overall treatment time (OTT) in a well-described sequential therapy paradigm for locally advanced head-and-neck carcinoma (LAHNC). Methods and Materials: TAX 324 is a Phase III study comparing TPF (docetaxel, cisplatin, and fluorouracil) with PF (cisplatin and fluorouracil) induction chemotherapy (IC) in LAHNC patients; both arms were followed by carboplatin-based chemoradiotherapy (CRT). Prospective radiotherapy quality assurance was performed. This analysis includes all patients who received three cycles of IC and a radiation dose of {>=} 70 Gy. Radiotherapy treatment time was analyzed as binary ({<=} 8more » weeks vs. longer) and continuous (number of days beyond 8 weeks) functions. The primary analysis assessed the relationship between RTT, OTT, and OS, and the secondary analysis explored the association between treatment times and locoregional recurrence (LRR). Results: A total of 333 (of 501) TAX 324 patients met the criteria for inclusion in this analysis. There were no significant differences between the treatment arms in baseline or treatment characteristics. On multivariable analysis, PF IC, World Health Organization performance status of 1, non-oropharynx site, T3/4 stage, N3 status, and prolonged RTT (hazard ratio 1.63, p = 0.006) were associated with significantly inferior survival. Performance status, T3/4 disease, and prolonged RTT (odds ratio 1.68, p = 0.047) were independently and negatively related to LRR on multivariable analysis, whereas PF was not. Overall treatment time was not independently associated with either OS or LRR. Conclusions: In this secondary analysis of the TAX 324 trial, TPF IC remains superior to PF IC after controlling for radiotherapy delivery time. Even with optimal IC and concurrent chemotherapy, a non-prolonged RTT is a crucial determinant of treatment success. Appropriate delivery of radiotherapy after IC remains essential for optimizing OS in LAHNC.« less

Order parameter analysis of synchronization transitions on star networks

NASA Astrophysics Data System (ADS)

Chen, Hong-Bin; Sun, Yu-Ting; Gao, Jian; Xu, Can; Zheng, Zhi-Gang

2017-12-01

The collective behaviors of populations of coupled oscillators have attracted significant attention in recent years. In this paper, an order parameter approach is proposed to study the low-dimensional dynamical mechanism of collective synchronizations, by adopting the star-topology of coupled oscillators as a prototype system. The order parameter equation of star-linked phase oscillators can be obtained in terms of the Watanabe-Strogatz transformation, Ott-Antonsen ansatz, and the ensemble order parameter approach. Different solutions of the order parameter equation correspond to the diverse collective states, and different bifurcations reveal various transitions among these collective states. The properties of various transitions in the star-network model are revealed by using tools of nonlinear dynamics such as time reversibility analysis and linear stability analysis.

Using Concurrent Cardiovascular Information to Augment Survival Time Data from Orthostatic Tilt Tests

NASA Technical Reports Server (NTRS)

Feiveson, Alan H.; Fiedler, James; Lee, Stuart M. M.; Westby, Christian M.; Stenger, Michael B.; Platts, Steven H.

2014-01-01

Orthostatic Intolerance (OI) is the propensity to develop symptoms of fainting during upright standing. OI is associated with changes in heart rate, blood pressure and other measures of cardiac function. Problem: NASA astronauts have shown increased susceptibility to OI on return from space missions. Current methods for counteracting OI in astronauts include fluid loading and the use of compression garments. Multivariate trajectory spread is greater as OI increases. Pairwise comparisons at the same time within subjects allows incorporation of pass/fail outcomes. Path length, convex hull area, and covariance matrix determinant do well as statistics to summarize this spread Missing data problems Time series analysis need many more time points per OTT session treatment of trend? how incorporate survival information?

Collective phase response curves for heterogeneous coupled oscillators

NASA Astrophysics Data System (ADS)

Hannay, Kevin M.; Booth, Victoria; Forger, Daniel B.

2015-08-01

Phase response curves (PRCs) have become an indispensable tool in understanding the entrainment and synchronization of biological oscillators. However, biological oscillators are often found in large coupled heterogeneous systems and the variable of physiological importance is the collective rhythm resulting from an aggregation of the individual oscillations. To study this phenomena we consider phase resetting of the collective rhythm for large ensembles of globally coupled Sakaguchi-Kuramoto oscillators. Making use of Ott-Antonsen theory we derive an asymptotically valid analytic formula for the collective PRC. A result of this analysis is a characteristic scaling for the change in the amplitude and entrainment points for the collective PRC compared to the individual oscillator PRC. We support the analytical findings with numerical evidence and demonstrate the applicability of the theory to large ensembles of coupled neuronal oscillators.

[The problems of assessment of the high noise impact on the experts of the Air Force].

PubMed

Zinkin, V N; Sheshegov, P M

2012-01-01

Air Force specialists are exposed to high intensity noise levels exceeded the maximum permissible levels. Infrasound as a productive factor in accordance with the general technical requirements (OTT) Air Force-86 is not included in the list of standardized factors. The adverse acoustic environment makes the risk of occupational (sensorineural deafness) and professionally-related diseases of the nervous and cardiovascular systems. The system of physical fitness for military service in the Air Force and serving in the Air Force with high-intensity sources of noise, the system of treatment and preventive measures for adverse effects of noise and the procedure for examination of persons with diseases caused by the influence of noise are needed to be reviewed in accordance with the existing state legislative frameworks.

Chaotic dynamics in the physical sciences (Lewis Fry Richardson Medal Lecture)

NASA Astrophysics Data System (ADS)

Ott, Edward

2017-04-01

Chaos was discovered at the end of the 19th century by Poincare in his famous work on the motion of N>2 celestial bodies interacting through gravitational attraction. Although steady progress was made by mathematicians following Poincare's work, the widespread impact and development of chaos in the physical sciences is comparatively recent, i.e., approximately starting in the 1970's. This talk will review and comment on this history and will give some examples illustrating the types of questions, problems and results arising from perspectives resulting from the widespread participation of physical scientists in chaos research. One of these examples will be from our work on data assimilation for weather prediction [ Ott et al., Tellus A vol.56, 415 (2004); Patil, Phys. Rev. Lett. vol.86, 5878 (2001)].

Chimera and modulated drift states in a ring of nonlocally coupled oscillators with heterogeneous phase lags

NASA Astrophysics Data System (ADS)

Choe, Chol-Ung; Kim, Ryong-Son; Ri, Ji-Song

2017-09-01

We consider a ring of phase oscillators with nonlocal coupling strength and heterogeneous phase lags. We analyze the effects of heterogeneity in the phase lags on the existence and stability of a variety of steady states. A nonlocal coupling with heterogeneous phase lags that allows the system to be solved analytically is suggested and the stability of solutions along the Ott-Antonsen invariant manifold is explored. We present a complete bifurcation diagram for stationary patterns including the uniform drift and modulated drift states as well as chimera state, which reveals that the stable modulated drift state and a continuum of metastable drift states could occur due to the heterogeneity of the phase lags. We verify our theoretical results using the direct numerical simulations of the model system.

Supercritical Wing Preliminary Design Study

DTIC Science & Technology

1975-12-01

SHIN «" NOME« <i./t. TAK t«/C» Ttff MA. TAft 4P) JON*« SO M »<• n y »■« • ii n VT«t 4il rtt-Tin J.l.. .S • T» 4...UPM At 1 54 ;t’ -"fi Vitll TI|K EMS IQH A4 ZEE TAff i>^ /tr TAfE <!•/£► TAK KOMUl CUJT« ■no pl TfJK A« *>1» FT J’ T<»£ 511...N« AMT* Oa/tr I» MB »AIM NO. NO. MATEWAL n «ttr ASSY Ott».!. -1 fio.if 5»»« J («It» TAK , I 1 ftf»6 Sf»* »" Cit/t»T««l

Polarization of Lyman-Alpha Radiation from Atomic Hydrogen Excited by Electron Impact form Near Threshold to 1800 eV

NASA Technical Reports Server (NTRS)

James, G. K.; Slevin, J. A.; Dziczek, D.; McConkey, J. W.; Bray, Igor

1998-01-01

The polarization of Lyman-a radiation, produced by electron-impact excitation of atomic hydrogen, has been measured over the extended energy range from near threshold to 1800 eV. Measurements were obtained in a crossed-beam experiment using a silica-reflection linear polarization analyzer in tandem with a vacuum-ultraviolet monochromator to isolate the emitted line radiation. Comparison with various theoretical calculations shows that the present experimental results are in good agreement with theory over the entire range of electron-impact energies and, in particular, are in excellent agreement with theoretical convergent-close-coupling (CCC) calculations performed in the present work. Our polarization data are significantly different from the previous experimental measurements of Ott, Kauppila, and Fite.

An Event-based Assessment of Uncertainty in Measurements Between Multiple Precipitation Sensors During the North American Monsoon

NASA Astrophysics Data System (ADS)

Kautz, M. A.; Keefer, T.; Demaria, E. M.; Goodrich, D. C.; Hazenberg, P.; Petersen, W. A.; Wingo, M. T.; Smith, J.

2017-12-01

The USDA - Agricultural Research Service (USDA-ARS) Long-Term Agroecosystem Research network (LTAR) is a partnership between 18 long-term research sites across the United States. As part of the program, LTAR aims to assemble a network of common sensors and measurements of hydrological, meteorological, and biophysical variables to accompany the legacy datasets of individual LTAR sites. Uncertainty remains as to how the common sensor-based measurements will compare to those measured with existing sensors at each site. The USDA-ARS Southwest Watershed Research Center (SWRC) operated Walnut Gulch Experimental Watershed (WGEW) represents the semiarid grazing lands located in southeastern Arizona in the LTAR network. The bimodal precipitation regime of this region is characterized by large-scale frontal precipitation in the winter and isolated, high-intensity, convective thunderstorms in the summer during the North American Monsoon (NAM). SWRC maintains a network of 90 rain gauges across the 150 km2 WGEW and surrounding area, with measurements dating back to the 1950's. The high intensity and isolated nature of the summer storms has historically made it difficult to quantify compared to other regimes in the US. This study assesses the uncertainty of measurement between the common LTAR Belfort All Weather Precipitation Gauge (AEPG 600) and the legacy WGEW weighing-type raingage. Additionally, in a collaboration with NASA Global Precipitation Measurement mission (GPM) and the University of Arizona a dense array of precipitation measuring sensors was installed at WGEW within a 10 meter radius for observation during the NAM, July through October 2017. In addition to two WGEW weighing-type gauges, the array includes: an AEPG 600, a tipping bucket, a weighing-bucket installed with orifice at ground level, an OTT Pluvio2 rain gauge, a Two-Dimensional Video Disdrometer (2DVD), and three OTT Parsivel2 disdrometers. An event-based comparison was made between precipitation sensors using metrics including total depth, peak intensity (1, 15, 30, and 60 minute), event duration, time to peak intensity, and start time of event. These results provide further insight into the uncertainties of measuring point-based precipitation in this unique precipitation regime and representation in large-scale observation networks.

Nonsyndromic cleft lip with or without cleft palate: New BCL3 information

DOE Office of Scientific and Technical Information (OSTI.GOV)

Amos, C.; Hecht, J.T.; Gasser, D.

1996-09-01

We did not previously provide LOD scores for linkage assuming heterogeneity, as suggested by Ott for the linkage analysis of cleft lip with or without cleft palate (CL/P) and BCL3, ApoC2, and D19S178 in the paper by Stein et al. The results from analysis using the HOMOG program, allowing for heterogeneity under the reduced penetrance model, gave a maximum LOD score of 1.85 for ApoC2, 0.41 for BCL3, 0.03 for D19S178, and 1.72 for multipoint analysis in the interval. For the affecteds-only model, the values are 1.96 for ApoC2, 0.41 for BCL3, 0.01 for D19S178, and 1.44 for the multipointmore » analysis. 8 refs.« less

Resynchronization of circadian oscillators and the east-west asymmetry of jet-lag

NASA Astrophysics Data System (ADS)

Lu, Zhixin; Klein-Cardeña, Kevin; Lee, Steven; Antonsen, Thomas M.; Girvan, Michelle; Ott, Edward

2016-09-01

Cells in the brain's Suprachiasmatic Nucleus (SCN) are known to regulate circadian rhythms in mammals. We model synchronization of SCN cells using the forced Kuramoto model, which consists of a large population of coupled phase oscillators (modeling individual SCN cells) with heterogeneous intrinsic frequencies and external periodic forcing. Here, the periodic forcing models diurnally varying external inputs such as sunrise, sunset, and alarm clocks. We reduce the dimensionality of the system using the ansatz of Ott and Antonsen and then study the effect of a sudden change of clock phase to simulate cross-time-zone travel. We estimate model parameters from previous biological experiments. By examining the phase space dynamics of the model, we study the mechanism leading to the difference typically experienced in the severity of jet-lag resulting from eastward and westward travel.

Electron microscopy of carbonaceous matter in Allende acid residues

NASA Technical Reports Server (NTRS)

Lumpkin, G. R.

1982-01-01

On the basis of characteristic diffuse ring diffraction patterns, much of the carbonaceous matter in a large suite of Allende acid residues has been identified as a variety of turbostratic carbon. Crystallites of this phase contain randomly stacked sp(2) hybridized carbon layers and diffraction patterns resemble those from carbon black and glassy carbon. Carbynes are probably absent, and are certainly restricted to less than 0.5% of these acid residues. The work of Ott et al. (1981) provides a basis for the possibility that turbostratic carbon is a carrier of noble gases, but an additional component - amorphous carbon - may be necessary to explain the high release temperatures of noble gases as well as the glassy character of many of the carbonaceous particles. Carbynes are considered to be questionable as important carriers of noble gases in the Allende acid residues.

Null Filter Mobile Radar (NFMRAD): Concept Verification,

DTIC Science & Technology

1980-10-01

i ~ I t\\-~~iA \\-ti mitt Ir t!1 iil -it i 5 sh, \\ iIi : oil I III j tta i I, l I i i 1 :2)1 cfi i Iu ,ft vli tiiiht -ln r.t Anel t I ItIit ott!1 l vI...littIiS aI t ed )ki toe t I ( it I I, (t edsIn oil -u iletit ilthe li trilcoii, tile. I end 11c.d I [lht tx% t .I i Iii t ia Il (ila I s vst eli I S CS...appiiriate crrrectioin factors, and tiltitorrial iy~ oil pr’oc’edurec is c’rtliple’t. 17o calulat air antenna ratter, i’terall’t several I. to 1ii) ’i’reods

Network architecture in a converged optical + IP network

NASA Astrophysics Data System (ADS)

Wakim, Walid; Zottmann, Harald

2012-01-01

As demands on Provider Networks continue to grow at exponential rates, providers are forced to evaluate how to continue to grow the network while increasing service velocity, enhancing resiliency while decreasing the total cost of ownership (TCO). The bandwidth growth that networks are experiencing is in the form packet based multimedia services such as video, video conferencing, gaming, etc... mixed with Over the Top (OTT) content providers such as Netflix, and the customer's expectations that best effort is not enough you end up with a situation that forces the provider to analyze how to gain more out of the network with less cost. In this paper we will discuss changes in the network that are driving us to a tighter integration between packet and optical layers and how to improve on today's multi - layer inefficiencies to drive down network TCO and provide for a fully integrated and dynamic network that will decrease time to revenue.

Conformists and contrarians in a Kuramoto model with identical natural frequencies

NASA Astrophysics Data System (ADS)

Hong, Hyunsuk; Strogatz, Steven H.

2011-10-01

We consider a variant of the Kuramoto model in which all the oscillators are now assumed to have the same natural frequency, but some of them are negatively coupled to the mean field. These contrarian oscillators tend to align in antiphase with the mean field, whereas, the positively coupled conformist oscillators favor an in-phase relationship. The interplay between these effects can lead to rich dynamics. In addition to a splitting of the population into two diametrically opposed factions, the system can also display traveling waves, complete incoherence, and a blurred version of the two-faction state. Exact solutions for these states and their bifurcations are obtained by means of the Watanabe-Strogatz transformation and the Ott-Antonsen ansatz. Curiously, this system of oscillators with identical frequencies turns out to exhibit more complicated dynamics than its counterpart with heterogeneous natural frequencies.

Dynamics of weakly inhomogeneous oscillator populations: perturbation theory on top of Watanabe-Strogatz integrability

NASA Astrophysics Data System (ADS)

Vlasov, Vladimir; Rosenblum, Michael; Pikovsky, Arkady

2016-08-01

As has been shown by Watanabe and Strogatz (WS) (1993 Phys. Rev. Lett. 70 2391), a population of identical phase oscillators, sine-coupled to a common field, is a partially integrable system: for any ensemble size its dynamics reduce to equations for three collective variables. Here we develop a perturbation approach for weakly nonidentical ensembles. We calculate corrections to the WS dynamics for two types of perturbations: those due to a distribution of natural frequencies and of forcing terms, and those due to small white noise. We demonstrate that in both cases, the complex mean field for which the dynamical equations are written is close to the Kuramoto order parameter, up to the leading order in the perturbation. This supports the validity of the dynamical reduction suggested by Ott and Antonsen (2008 Chaos 18 037113) for weakly inhomogeneous populations.

Conformists and contrarians in a Kuramoto model with identical natural frequencies.

PubMed

Hong, Hyunsuk; Strogatz, Steven H

2011-10-01

We consider a variant of the Kuramoto model in which all the oscillators are now assumed to have the same natural frequency, but some of them are negatively coupled to the mean field. These contrarian oscillators tend to align in antiphase with the mean field, whereas, the positively coupled conformist oscillators favor an in-phase relationship. The interplay between these effects can lead to rich dynamics. In addition to a splitting of the population into two diametrically opposed factions, the system can also display traveling waves, complete incoherence, and a blurred version of the two-faction state. Exact solutions for these states and their bifurcations are obtained by means of the Watanabe-Strogatz transformation and the Ott-Antonsen ansatz. Curiously, this system of oscillators with identical frequencies turns out to exhibit more complicated dynamics than its counterpart with heterogeneous natural frequencies.

The type specimen and generic placement of Tridactylus galla Saussure, 1895 (Orthoptera: Caelifera: Tridactylidae).

PubMed

Heads, Sam W; Hollier, John

2016-11-15

Tridactylus galla was described by Henri de Saussure (1895) on the basis of a single adult female collected during Vittorio Bottego's first expedition to the Horn of Africa in 1892 and 1893. The species appears in lists compiled by Fenizia (1896), Lucas (1898) and Kirby (1906), but aside from a brief mention by Günther (1995), is entirely overlooked by subsequent authors and is absent from Otte's (1997) catalogue. During the course of compiling an annotated catalogue of the Orthoptera described by Saussure (Hollier and Heads, 2012) we were able to relocate the type of Tridactylus galla in the collection of the Museo Civico di Storia Naturale "Giacomo Doria" in Genova, Italy. Our examination of the specimen confirmed Günther's (1995) assertion that its placement in Tridactylus Olivier, 1789 is erroneous, and the species is herein formally transferred to the genus Xya Latreille, 1809.

Tissue procurement and transplantation: a Tuscany perspective.

PubMed

Filipponi, F; De Simone, P; Saviozzi, A; Bozzi, G

2008-01-01

Tissue procurement and transplantation are rarely taken into account as indicators of the efficiency of a regional donor procurement network. We present herein a retrospective review on Tuscany tissue procurement activities from 2004 until 2006. In 2003 the Tuscan Regional Government appointed a transplantation service authority to reorganize all regional donation and transplantation activities: the Organizzazione Toscana Trapianti (OTT). The regional tissue procurement network was based on either brain death (BD) and cardiac death (CD) donors under the responsibility of in-hospital transplantation coordinators (IHTCs). From 2004 to 2006, a total of 397 tissue donors were procured in Tuscany, and 4151 tissue transplantations were performed: 2909 skin grafts, 1209 bone grafts, and 33 heart valves. Over the same period, a total of 2116 cornea donors were procured; 4117 corneas were retrieved; 1779 were fit for transplantation, and 1418 were transplanted. Based on our experience, implementation of tissue procurement requires use of BD donors and paramount organizational efforts from IHTCs.

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, FY 88. Part 4. (Burnside-Ott Avi. Training Ctr.-Colcom, Inc.)

DTIC Science & Technology

1988-01-01

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Synchronization scenarios in the Winfree model of coupled oscillators

NASA Astrophysics Data System (ADS)

Gallego, Rafael; Montbrió, Ernest; Pazó, Diego

2017-10-01

Fifty years ago Arthur Winfree proposed a deeply influential mean-field model for the collective synchronization of large populations of phase oscillators. Here we provide a detailed analysis of the model for some special, analytically tractable cases. Adopting the thermodynamic limit, we derive an ordinary differential equation that exactly describes the temporal evolution of the macroscopic variables in the Ott-Antonsen invariant manifold. The low-dimensional model is then thoroughly investigated for a variety of pulse types and sinusoidal phase response curves (PRCs). Two structurally different synchronization scenarios are found, which are linked via the mutation of a Bogdanov-Takens point. From our results, we infer a general rule of thumb relating pulse shape and PRC offset with each scenario. Finally, we compare the exact synchronization threshold with the prediction of the averaging approximation given by the Kuramoto-Sakaguchi model. At the leading order, the discrepancy appears to behave as an odd function of the PRC offset.

Hydrometry's classical and Innovative methods and tools comparison for Stara river flows at Agios Germanos monitoring station in north-west Greece.

NASA Astrophysics Data System (ADS)

Filintas, Agathos, , Dr; Hatzigiannakis, Evagellos, , Dr; Arampatzis, George, , Dr; Ilias, Andreas; Panagopoulos, Andreas, , Dr; Hatzispiroglou, Ioannis

2015-04-01

The aim of the present study is a thorough comparison of hydrometry's conventional and innovative methods-tools for river flow monitoring. A case study was conducted in Stara river at Agios Germanos monitoring station (northwest Greece), in order to investigate possible deviations between conventional and innovative methods-tools on river flow velocity and discharge. For this study, two flowmeters were used, which manufac-tured in 2013 (OTT Messtechnik Gmbh, 2013), as follows: a) A conventional propeller flow velocity meter (OTT-Model C2) which is a me-chanical current flow meter with a certification of calibration BARGO, operated with a rod and a relocating device, along with a digital measuring device including an elec-tronic flow calculator, data logger and real time control display unit. The flowmeter has a measurement velocity range 0.025-4.000 m/s. b) An innovative electromagnetic flowmeter (OTT-Model MF pro) which it is con-sisted of a compact and light-weight sensor and a robust handheld unit. Both system components are designed to be attached to conventional wading rods. The electromag-netic flowmeter uses Faraday's Law of electromagnetic induction to measure the process flow. When an electrically conductive fluid flows along the meter, an electrode voltage is induced between a pair of electrodes placed at right angles to the direction of mag-netic field. The electrode voltage is directly proportional to the average fluid velocity. The electromagnetic flowmeter was operated with a rod and relocating device, along with a digital measuring device with various logging and graphical capabilities and vari-ous methods of velocity measurement (ISO/USGS standards). The flowmeter has a measurement velocity range 0.000-6.000 m/s. The river flow data were averaged over a pair measurement of 60+60 seconds and the measured river water flow velocity, depths and widths of the segments were used for the estimation of cross-section's mean flow velocity in each measured segment. Then it was used the mid-section method for the overall discharge calculation of all segments flow area. The cross-section characteristics, the river flow velocity of segments and the mean water flow velocity and discharge total profile were measured, calculated and an-notated respectively. A series of concurrent conventional and innovative (electromag-netic) flow measurements were performed during 2014. The results and statistical analysis showed that Froude number during the measurement period in all cases was Fr<1 which means that the water flow of the Stara river is classified as subcritical flow. The 12 months' study showed various advantages for the elec-tromagnetic sensor that is virtually maintenance-free because there are no moving parts, no calibration was required in practice, and it can be used even in the lowest water ve-locities from 0.000 m/s. Moreover, based on the concurrent hydromeasurements of the Stara River, on the velocity and discharge modelling and the statistical analysis, it was found that there was not a significant statistical difference (α=0.05) between mean velocity measured with a) conventional and b) electromagnetic method which seems to be more accurate in low velocities where a significant statistical difference was found. Acknowledgments Data in this study are collected in the framework of the elaboration of the national water resources monitoring network, supervised by the Special Secretariat for Water-Hellenic Ministry for the Environment and Climate Change. This project is elaborated in the framework of the operational program "Environment and Sustainable Development" which is co-funded by the National Strategic Reference Framework (NSRF) and the Public Investment Program (PIP).

Somatic hypermutation of T cell receptor α chain contributes to selection in nurse shark thymus.

PubMed

Ott, Jeannine A; Castro, Caitlin D; Deiss, Thaddeus C; Ohta, Yuko; Flajnik, Martin F; Criscitiello, Michael F

2018-04-17

Since the discovery of the T cell receptor (TcR), immunologists have assigned somatic hypermutation (SHM) as a mechanism employed solely by B cells to diversify their antigen receptors. Remarkably, we found SHM acting in the thymus on α chain locus of shark TcR. SHM in developing shark T cells likely is catalyzed by activation-induced cytidine deaminase (AID) and results in both point and tandem mutations that accumulate non-conservative amino acid replacements within complementarity-determining regions (CDRs). Mutation frequency at TcRα was as high as that seen at B cell receptor loci (BcR) in sharks and mammals, and the mechanism of SHM shares unique characteristics first detected at shark BcR loci. Additionally, fluorescence in situ hybridization showed the strongest AID expression in thymic corticomedullary junction and medulla. We suggest that TcRα utilizes SHM to broaden diversification of the primary αβ T cell repertoire in sharks, the first reported use in vertebrates. © 2018, Ott et al.

Pharmacokinetics Application in Biophysics Experiments

NASA Astrophysics Data System (ADS)

Millet, Philippe; Lemoigne, Yves

Among the available computerised tomography devices, the Positron Emission Tomography (PET) has the advantage to be sensitive to pico-molar concentrations of radiotracers inside living matter. Devices adapted to small animal imaging are now commercially available and allow us to study the function rather than the structure of living tissues by in vivo analysis. PET methodology, from the physics of electron-positron annihilation to the biophysics involved in tracers, is treated by other authors in this book. The basics of coincidence detection, image reconstruction, spatial resolution and sensitivity are discussed in the paper by R. Ott. The use of compartment analysis combined with pharmacokinetics is described here to illustrate an application to neuroimaging and to show how parametric imaging can bring insight on the in vivo bio-distribution of a radioactive tracer with small animal PET scanners. After reporting on the use of an intracerebral β+ radiosensitive probe (βP), we describe a small animal PET experiment used to measure the density of 5HT 1 a receptors in rat brain.

Frequency and phase synchronization in large groups: Low dimensional description of synchronized clapping, firefly flashing, and cricket chirping

NASA Astrophysics Data System (ADS)

Ott, Edward; Antonsen, Thomas M.

2017-05-01

A common observation is that large groups of oscillatory biological units often have the ability to synchronize. A paradigmatic model of such behavior is provided by the Kuramoto model, which achieves synchronization through coupling of the phase dynamics of individual oscillators, while each oscillator maintains a different constant inherent natural frequency. Here we consider the biologically likely possibility that the oscillatory units may be capable of enhancing their synchronization ability by adaptive frequency dynamics. We propose a simple augmentation of the Kuramoto model which does this. We also show that, by the use of a previously developed technique [Ott and Antonsen, Chaos 18, 037113 (2008)], it is possible to reduce the resulting dynamics to a lower dimensional system for the macroscopic evolution of the oscillator ensemble. By employing this reduction, we investigate the dynamics of our system, finding a characteristic hysteretic behavior and enhancement of the quality of the achieved synchronization.

Multiple-parameter bifurcation analysis in a Kuramoto model with time delay and distributed shear

NASA Astrophysics Data System (ADS)

Niu, Ben; Zhang, Jiaming; Wei, Junjie

2018-05-01

In this paper, time delay effect and distributed shear are considered in the Kuramoto model. On the Ott-Antonsen's manifold, through analyzing the associated characteristic equation of the reduced functional differential equation, the stability boundary of the incoherent state is derived in multiple-parameter space. Moreover, very rich dynamical behavior such as stability switches inducing synchronization switches can occur in this equation. With the loss of stability, Hopf bifurcating coherent states arise, and the criticality of Hopf bifurcations is determined by applying the normal form theory and the center manifold theorem. On one hand, theoretical analysis indicates that the width of shear distribution and time delay can both eliminate the synchronization then lead the Kuramoto model to incoherence. On the other, time delay can induce several coexisting coherent states. Finally, some numerical simulations are given to support the obtained results where several bifurcation diagrams are drawn, and the effect of time delay and shear is discussed.

Optimal synchronization of Kuramoto oscillators: A dimensional reduction approach

NASA Astrophysics Data System (ADS)

Pinto, Rafael S.; Saa, Alberto

2015-12-01

A recently proposed dimensional reduction approach for studying synchronization in the Kuramoto model is employed to build optimal network topologies to favor or to suppress synchronization. The approach is based in the introduction of a collective coordinate for the time evolution of the phase locked oscillators, in the spirit of the Ott-Antonsen ansatz. We show that the optimal synchronization of a Kuramoto network demands the maximization of the quadratic function ωTL ω , where ω stands for the vector of the natural frequencies of the oscillators and L for the network Laplacian matrix. Many recently obtained numerical results can be reobtained analytically and in a simpler way from our maximization condition. A computationally efficient hill climb rewiring algorithm is proposed to generate networks with optimal synchronization properties. Our approach can be easily adapted to the case of the Kuramoto models with both attractive and repulsive interactions, and again many recent numerical results can be rederived in a simpler and clearer analytical manner.

Avoiding the Health Hazard of People from Construction Vehicles: A Strategy for Controlling the Vibration of a Wheel Loader

PubMed Central

Chi, Feng; Zhou, Jun; Zhang, Qi; Wang, Yong; Huang, Panling

2017-01-01

The vibration control of a construction vehicle must be carried out in order to meet the aims of sustainable environmental development and to avoid the potential human health hazards. In this paper, based on market feedback, the driver seat vibration of a type of wheel loader in the left and right direction, is found to be significant over a certain speed range. In order to find abnormal vibration components, the order tracking technique (OTT) and transmission path analysis (TPA) were used to analyze the vibration sources of the wheel loader. Through this analysis, it can be seen that the abnormal vibration comes from the interaction between the tire tread and the road, and this is because the vibration was amplified by the cab mount, which was eventually transmitted to the cab seat. Finally, the seat vibration amplitudes were decreased by up to 50.8%, after implementing the vibration reduction strategy. PMID:28282849

Probing the statistics of transport in the Hénon Map

NASA Astrophysics Data System (ADS)

Alus, O.; Fishman, S.; Meiss, J. D.

2016-09-01

The phase space of an area-preserving map typically contains infinitely many elliptic islands embedded in a chaotic sea. Orbits near the boundary of a chaotic region have been observed to stick for long times, strongly influencing their transport properties. The boundary is composed of invariant "boundary circles." We briefly report recent results of the distribution of rotation numbers of boundary circles for the Hénon quadratic map and show that the probability of occurrence of small integer entries of their continued fraction expansions is larger than would be expected for a number chosen at random. However, large integer entries occur with probabilities distributed proportionally to the random case. The probability distributions of ratios of fluxes through island chains is reported as well. These island chains are neighbours in the sense of the Meiss-Ott Markov-tree model. Two distinct universality families are found. The distributions of the ratio between the flux and orbital period are also presented. All of these results have implications for models of transport in mixed phase space.

Chimera states in spatiotemporal systems: Theory and Applications

NASA Astrophysics Data System (ADS)

Yao, Nan; Zheng, Zhigang

2016-03-01

In this paper, we propose a retrospective and summary on recent studies of chimera states. Chimera states demonstrate striking inhomogeneous spatiotemporal patterns emerging in homogeneous systems through unexpected spontaneous symmetry breaking, where the consequent spatiotemporal patterns are composed of both coherence and incoherence domains, respectively characterized by the synchronized and desynchronized motions of oscillators. Since the discovery of chimera states by Kuramoto and others, this striking collective behavior has attracted a great deal of research interest in the community of physics and related interdisciplinary fields from both theoretical and experimental viewpoints. In recent works exploring chimera states, rich phenomena such as the spiral wave chimera, multiple cluster chimera, amplitude chimera were observed from various types of model systems. Theoretical framework by means of self-consistency approach and Ott-Antonsen approach were proposed for further understanding to this symmetry-breaking-induced behavior. The stability and robustness of chimera states were also discussed. More importantly, experiments ranging from optical, chemical to mechanical designs successfully approve the existence of chimera states.

Avoiding the Health Hazard of People from Construction Vehicles: A Strategy for Controlling the Vibration of a Wheel Loader.

PubMed

Chi, Feng; Zhou, Jun; Zhang, Qi; Wang, Yong; Huang, Panling

2017-03-08

The vibration control of a construction vehicle must be carried out in order to meet the aims of sustainable environmental development and to avoid the potential human health hazards. In this paper, based on market feedback, the driver seat vibration of a type of wheel loader in the left and right direction, is found to be significant over a certain speed range. In order to find abnormal vibration components, the order tracking technique (OTT) and transmission path analysis (TPA) were used to analyze the vibration sources of the wheel loader. Through this analysis, it can be seen that the abnormal vibration comes from the interaction between the tire tread and the road, and this is because the vibration was amplified by the cab mount, which was eventually transmitted to the cab seat. Finally, the seat vibration amplitudes were decreased by up to 50.8%, after implementing the vibration reduction strategy.

Widely Dispersed Tephra of Toba Mega-Eruptions in the Indian Ocean

NASA Astrophysics Data System (ADS)

Chen, C.; Lee, M.; Iizuka, Y.; Dehn, J.; Song, S.; Yang, F.

2001-12-01

The tephra layers recovered in the Quaternary sediments of Ocean Drilling Program (ODP) Leg 121 Site 758 provide the best record of Toba mega-eruptions in Sumatra, Indonesia. Site 758, located at 5o23.05¡œN, 90o21.67¡œE on the crest of Ninetyeast Ridge with 2924 m water depth, is approximately 1000 km west from the Toba caldera. Four tephra layers in the last 1.5 Ma were recognized as the products of the Toba caldera eruptions, based on chemical and isotopic compositions of the glass shards and minerals. These four tephra layers are named as A, C, D and F layers by Dehn et al. (1991), respectively. The glass shards in these tephra layers related to Toba eruptions showed much higher K2O (>4.5%) and lower CaO (<0.8%) contents, therefore pointing out great differences from the corresponding values of other ashes originating in the Philippines (e.g. glass in the SCS from Mt Pinatubo, K2O<3.0% and CaO>1.1%, SiO2 ~77% Wiesner et al., 1995). Moreover, the biotite grains in these tephra layers showed that the FeO content was higher than the MgO content. The isotopic composition of glass shards is the best fingerprint to trace the source rock. The glass shard fragments revealed extremely high 87Sr/86Sr values (0.71384-0.71869); As for the Sr isotopic values, the Youngest Toba Tuff (YTT) and the Oldest Toba Tuff (OTT) in the Sumatra and the IMAGES Cores in the South China Sea also showed high values from 0.7128-0.7152 (Chesner, 1988; Song et al., 2000; Chen et al., 2000, 2001). The tephrochronology of four tephra layers was re-estimated, based on the new Oxygen proxies. The ages of the A, C, D and F layers in the Site 758 were 0.075 Ma, 0.49 Ma, 0.80 Ma and 1.41 Ma, respectively, which could well correspond to the YTT, the Middle Toba Tuff (MTT), the OTT and the Haranggoal Dacite Tuff (HDT), respectively. This unique set of four wildly dispersed ash layers in the Indian Ocean will provide not only the important key beds in marine sedimentary sequence study in the Quaternary era, but a rare chance to speculate the relationship between the mega-eruptions and the long term global climate change in the natural laboratory.

Guest investigator program study: Physics of equatorial plasma bubbles

NASA Technical Reports Server (NTRS)

Tsunoda, Roland T.

1994-01-01

Plasma bubbles are large-scale (10 to 100 km) depletions in plasma density found in the night-time equatorial ionosphere. Their formation has been found to entail the upward transport of plasma over hundreds of kilometers in altitude, suggesting that bubbles play significant roles in the physics of many of the diverse and unique features found in the low-latitude ionosphere. In the simplest scenario, plasma bubbles appear first as perturbations in the bottomside F layer, which is linearly unstable to the gravitationally driven Rayleigh-Taylor instability. Once initiated, bubbles develop upward through the peak of the F layer into its topside (sometimes to altitudes in excess of 1000 km), a behavior predicted by the nonlinear form of the same instability. While good general agreement has been found between theory and observations, little is known about the detailed physics associated with plasma bubbles. Our research activity centered around two topics: the shape of plasma bubbles and associated electric fields, and the day-to-day variability in the occurrence of plasma bubbles. The first topic was pursued because of a divergence in view regarding the nonlinear physics associated with plasma bubble development. While the development of perturbations in isodensity contours in the bottomside F layer into plasma bubbles is well accepted, some believed bubbles to be cylinder-like closed regions of depleted plasma density that floated upward leaving a turbulent wake behind them (e.g., Woodman and LaHoz, 1976; Ott, 1978; Kelley and Ott, 1978). Our results, summarized in a paper submitted to the Journal of Geophysical Research, consisted of incoherent scatter radar measurements that showed unambiguously that the depleted region is wedgelike and not cylinderlike, and a case study and modeling of SM-D electric field instrument (EFI) measurements that showed that the absence of electric-field perturbations outside the plasma-depleted region is a distinct signature of wedge-shaped plasma bubbles. The second topic was pursued because the inability to predict the day-to-day occurrence of plasma bubbles indicated inadequate knowledge of the physics of plasma bubbles. An understanding of bubble formation requires an understanding of the roles of the various terms in the linearized growth rate of the collisional Rayleigh-Taylor instability. In our study, we examined electric-field perturbations found in SM-D EFI data and found that the seeding is more likely to be produced in the E region rather than the F region. The results of this investigation are presented in the Appendix of this report and will be submitted for publication in the Journal of Geophysical Research.

All-Manganite Tunnel Junctions with Interface-Induced Barrier Magnetism

NASA Astrophysics Data System (ADS)

Sefrioui, Zouhair

2011-03-01

The recent discovery of several unexpected phases at complex oxide interfaces is providing new insights into the physics of strongly correlated electron systems. The possibility of tailoring the electronic structure of such interfaces has triggered a great technological drive to functionalize them into devices. In this communication, we describe an alternative strategy to produce spin filtering by inducing a ferromagnetic insulating state in an ultrathin antiferromagnetic layer in contact with a ferromagnetic layer. This artificially induced spin filtering persists up to relatively high temperatures and operates at high applied bias voltages. The results suggest that after playing a key role in exchange-bias for spin-valves, uncompensated moments at engineered antiferromagnetic interfaces represent a novel route for generating highly spin-polarized currents with antiferromagnets. Work done in collaboration with M. Bibes, C. Carrétéro, A. Barthélémy (Unité Mixte de Physique CNRS/Thales, Campus de Polytechnique, 1, Avenue A. Fresnel, 91767 Palaiseau (France) and Université Paris-Sud, 91045 Orsay (France)), F.A. Cuellar, C. Visani, A. Rivera-Calzada, , C. León, J. Santamaria (Grupo de Física de Materiales Complejos, Universidad Complutense de Madrid, 28040 Madrid (Spain)), M.J. Calderón, L. Brey (Instituto de Ciencia de Materiales de Madrid, CSIC, Cantoblanco, 28049 Madrid (Spain)), K. March, M. Walls, D. Imhoff (Laboratoire de Physique des Solides, CNRS, Université Paris-Sud, 91405 Orsay (France)), R. Lopez Anton, T.R. Charlton (ISIS, Rutherford Appleton Laboratory, Chilton, Oxon OX11 0QX (United Kingdom)), E. Iborra (Universidad Politécnica de Madrid, Escuela Técnica Superior de Ingenieros de Telecomunicaciones, 28040 Madrid (Spain)), F. Ott (Léon Brillouin, CEA/CNRS, UMR 12, 91191 Gif-sur-Yvette (France)). This work was supported by the Spanish Ministry for Science and Education programs MAT2008 06517, and the Réseau Thématique de Recherche Avancée (RTRA) ``Triangle de la Physique.''

Simulations of Large-Area Electron Beam Diodes

NASA Astrophysics Data System (ADS)

Swanekamp, S. B.; Friedman, M.; Ludeking, L.; Smithe, D.; Obenschain, S. P.

1999-11-01

Large area electron beam diodes are typically used to pump the amplifiers of KrF lasers. Simulations of large-area electron beam diodes using the particle-in-cell code MAGIC3D have shown the electron flow in the diode to be unstable. Since this instability can potentially produce a non-uniform current and energy distribution in the hibachi structure and lasing medium it can be detrimental to laser efficiency. These results are similar to simulations performed using the ISIS code.(M.E. Jones and V.A. Thomas, Proceedings of the 8^th) International Conference on High-Power Particle Beams, 665 (1990). We have identified the instability as the so called ``transit-time" instability(C.K. Birdsall and W.B. Bridges, Electrodynamics of Diode Regions), (Academic Press, New York, 1966).^,(T.M. Antonsen, W.H. Miner, E. Ott, and A.T. Drobot, Phys. Fluids 27), 1257 (1984). and have investigated the role of the applied magnetic field and diode geometry. Experiments are underway to characterize the instability on the Nike KrF laser system and will be compared to simulation. Also some possible ways to mitigate the instability will be presented.

Noble Gases in Two Fragments of Different Lithologies from the Almahata Sitta Meteorite

NASA Technical Reports Server (NTRS)

Nagao, K.; Haba, M. K.; Zolensky, M.; Jenniskens, P.; Shaddad, M. H.

2014-01-01

The Almahata Sitta meteorite, whose preat-mospheric body was the asteroid 2008 TC3, fell on October 7, 2008 in the Nubian Desert in northern Sudan [e.g., 1, 2]. Numer-ous fragments have been recovered during several expeditions organized from December 2008 [2]. The meteorite was classified as an anomalous polymict ureilite with several different kinds of chondritic fragments [e.g., 3-5]. Noble gas studies performed on several fragments from the meteorite showed cosmic-ray expo-sure ages of about 20 My [e.g., 6-8], although slightly shorter ages were also reported in [9, 10]. Concentrations of trapped heavy noble gases are variable among the fragments of different lithologies [9, 10]. We report noble gas data on two samples from the #1 and #47 fragments [2], which were the same as those re-ported by Ott et al. [9]. Experimental Procedure: Weights of bulk samples #1 and #47 used in this work were 16.1 mg and 17.6 mg, respectively. Noble gases were extracted by stepwise heating at the tempera-tures of 800, 1200 and 1800°C for #1 and 600, 800, 1000, 1200, 1400, 1600 and 1800°C for #47. Concentrations and isotopic ra-tios of noble gases were measured with a modified-VG5400/MS-III at the Geochemical Research Center, University of Tokyo. Results and Discussion: Cosmogenic He and Ne are domi-nant in both #1 and #47, but trapped Ar, Kr and Xe concentra-tions are much higher in #47 than in #1, showing that noble gas compositions in #47 are similar to those of ureilites. 3He/21Ne and 22Ne/21Ne of cosmogenic He and Ne are 4.8 and 1.12 for #1 and 3.6 and 1.06 for #47, respectively, both of which plot on a Bern line [11]. This indicates negligible loss of cosmogenic 3He from #1 in our sample, unlike the low 3He/21Ne of 3.1 for #1 by Ott et al. [9]. Concentrations of cosmogenic 3He and 21Ne (10-8 cc/g) are 30 and 6.3 for #1 and 32 and 9.0 for #47, respectively, which are higher than those in [9] and give cosmic-ray exposure ages of ca. 20 My depending on assumed production rates. Rela-tive abundances of trapped 36Ar, 84Kr and 132Xe for #1 resemble those of Q-component, which is a dominant trapped noble gas component in chondrites. In contrast to #1, #47 plots below a trend for ureilites [12] as well as Q, which implies a partial loss of trapped 36Ar from the lithology of #47.

Detection of Lightning-produced NOx by Air Quality Monitoring Stations in Israel

NASA Astrophysics Data System (ADS)

Yair, Y.; Shalev, S.; Saaroni, H.; Ziv, B.

2011-12-01

Lightning is the largest natural source for the production of nitrogen oxides (LtNOx) in the troposphere. Since NOx are greenhouse gases, it is important to know the global production rate of LtNOx for climate studies (present estimates range from 2 to 8 Tg per year) and to model its vertical distribution (Ott et al., 2010). One of the key factors for such an estimate is the yield of a single lightning flash, namely the number of molecules produced for each Joule of energy deposited along the lightning channel. We used lightning stroke data from the Israel Lightning Location System (ILLS) together with NOx data obtained from the national network of air quality monitoring stations operated by the Israeli Ministry of Environmental Protection. Looking for the fingerprints of LtNOx in the general ambient concentrations, usually most affected by pollution from urban sources, we looked only for CG strokes occurring within a radius of 3 km from the location of an air-quality monitoring station. This lowered the number of relevant cases from 605,413 strokes detected in the 2004/5 through 2009/10 seasons to 1,897 strokes. We applied a threshold of > 60kA reducing the number of events to 35. The results showed that there was no consistent rising trend in the NOx concentrations in the hour following the lightning (the lifetime near the ground is expected to be a few hours; Zhang et al., 2003). However, when considering only those events when the prevailing wind was in the direction from the stroke location toward the sensor (7 cases), a clear increase of few ppb following the stroke was observed in 5 cases [see Fig.]. This increase is well correlated with the wind speed, suggesting an effective transport from the stroke location to the sensor. Weaker winds allow dilution and result in smaller observed increases of LtNOx. Separate analysis of additional 17 cases in which the strokes were located < 500 m from the monitoring station (with any peak current above 7 kA) showed no consistent trend. When excluding the 7 events that occurred during rush hour traffic, we found 6 (of 10) cases with an average increase in NOx concentrations of 16 ppb in the hour following the lightning. These results suggest a contribution of CG lightning strokes to the ground level concentrations of NOx. L. E. Ott, K. E. Pickering, G. L. Stenchikov, D. J. Allen, A. J. DeCaria, B. Ridley, R.F. Lin, S. Lang, and W.K. Tao (2010), Production of lightning NOx and its vertical distribution calculated from three dimensional cloud scale chemical transport model simulations, J. Geophys. Res., 115, D04301, doi:10.1029/2009JD011880

Preliminary microphysical characterization of precipitation at ground over Antarctica coast

NASA Astrophysics Data System (ADS)

Roberto, Nicoletta; Adirosi, Elisa; Montopoli, Mario; Baldini, Luca; Dietrich, Stefano; Porcù, Federico

2017-04-01

The primary mass input of the Antarctic ice sheet is snow precipitation which is one of the most direct climatic indicators. Climatic model simulations of precipitations over Antarctica is an important task to assess the variation of ice sheet over long temporal scale. The main source of precipitation information in Antarctica regions derive from satellite observations. However, satellite measurements and products need to be calibrated and validated with observations from ground sensors. In spite of their key role, precipitation measurements at ground are scarce and not appropriate to provide the specific characteristic of precipitation particles that influence the scattering and absorption properties of ice particles. Recently, different stations in Antarctica (Princess Elizabeth, McMurdo, Mario Zucchelli) are equipping observatories for cloud and precipitation observations. The setup of the observatory at the Italian Station, Mario Zucchelli (MZ) plans to integrate the current instrumentation for weather measurements with other instruments specific for precipitation observations, in particular, a 24-GHz vertical pointing radar and a laser disdrometer Parsivel. The synergetic use of the set of instruments allows for characterizing precipitation and studying properties of Antarctic precipitation such as dimension, shapes, fall behavior, density of particles, particles size distribution, particles terminal velocity, reflectivity factor and including some information on their vertical extent. Last November, the OTT Parsivel disdrometer was installed on the roof of a logistic container (at 6 m of height) of the MZ station (Latitude 74° 41' 42" S; Longitude 164° 07' 23E") in the Terranova Bay. The disdrometer measures size and fall velocity of particles, passing through a laser matrix from which the Particle Size Distribution (PSD) is obtained. In addition, some products such as reflectivity factor, snow rate and snow accumulation can be inferred by properly processing PSD spectra. Software provided by disdrometer manufacturer assumes spherical shape to compute the size and the fall velocity of the particle. In the case of solid precipitation, this assumption can be unrealistic. However, averaging over a long time the influence of irregular shape of the particles can be reduced. Despite this limit, the Parsivel disdrometer has been used in several study to measure falling snow. In this work, some preliminary measurements from OTT Parsivel at MSZ are presented. In particular, the PSD collected during summer season 2016-2017 are analyzed in order to infer microphysical characteristics of snows in Antarctica. A specific methodology to estimate the reflectivity factor and the snow rate from snow size spectra collected by Parsivel is investigated. Microphysical properties of Antarctica precipitating clouds, in particular PSD, are compared to measurements collected by disdrometer during snow events in other regions, such as the data collected during the GPM Cold-season Precipitation Experiment (GCPEx) in Ontario, Canada.

Delaying Orthostatic Syncope With Mental Challenge

NASA Astrophysics Data System (ADS)

Goswami, Nandu; Roessler, Andreas; Hinghofer-Szalkay, Helmut; Montani, Jean-Pierre; Steptoe, Andrew

2012-07-01

At orthostatic vasovagal syncope there appears to be a sudden withdrawl of sympathetic activity. As mental challenge activates the sympathetic system, we hypothesized that doing mental arithmetic in volunteers driven to the end point of their cardiovascular stability may delay the onset of orthostatic syncope. We investigated this in healthy male subjects. Each subject underwent a head up tilt (HUT) + graded lower body negative pressure (LBNP) up to presyncope session (control) to determine the orthostatic tolerance time, OTT (Time from HUT commencement to development of presyncopal symptoms/signs). Once the tolerance time was known, a randomized crossover protocol was used: either 1) Repeat HUT + LBNP to ensure reproducibility of repeated run or 2) HUT + LBNP run but with added mental challenge (two min before the expected presyncope time). Test protocols were separated by two weeks. Our studies on five male test subjects indicate that mental challenge improves orthostatic tolerance significantly. Additional mental loading could be a useful countermeasure to alleviate the orthostatic responses of persons, particularly in those with histories of dizziness on standing up, or to alleviate hypotension that frequently occurs during hemodialysis or on return to earth from the spaceflight environment of microgravity.

Adaptive control of dynamical synchronization on evolving networks with noise disturbances

NASA Astrophysics Data System (ADS)

Yuan, Wu-Jie; Zhou, Jian-Fang; Sendiña-Nadal, Irene; Boccaletti, Stefano; Wang, Zhen

2018-02-01

In real-world networked systems, the underlying structure is often affected by external and internal unforeseen factors, making its evolution typically inaccessible. An adaptive strategy was introduced for maintaining synchronization on unpredictably evolving networks [Sorrentino and Ott, Phys. Rev. Lett. 100, 114101 (2008), 10.1103/PhysRevLett.100.114101], which yet does not consider the noise disturbances widely existing in networks' environments. We provide here strategies to control dynamical synchronization on slowly and unpredictably evolving networks subjected to noise disturbances which are observed at the node and at the communication channel level. With our strategy, the nodes' coupling strength is adaptively adjusted with the aim of controlling synchronization, and according only to their received signal and noise disturbances. We first provide a theoretical analysis of the control scheme by introducing an error potential function to seek for the minimization of the synchronization error. Then, we show numerical experiments which verify our theoretical results. In particular, it is found that our adaptive strategy is effective even for the case in which the dynamics of the uncontrolled network would be explosive (i.e., the states of all the nodes would diverge to infinity).

Reynolds number dependence of relative dispersion statistics in isotropic turbulence

NASA Astrophysics Data System (ADS)

Sawford, Brian L.; Yeung, P. K.; Hackl, Jason F.

2008-06-01

Direct numerical simulation results for a range of relative dispersion statistics over Taylor-scale Reynolds numbers up to 650 are presented in an attempt to observe and quantify inertial subrange scaling and, in particular, Richardson's t3 law. The analysis includes the mean-square separation and a range of important but less-studied differential statistics for which the motion is defined relative to that at time t =0. It seeks to unambiguously identify and quantify the Richardson scaling by demonstrating convergence with both the Reynolds number and initial separation. According to these criteria, the standard compensated plots for these statistics in inertial subrange scaling show clear evidence of a Richardson range but with an imprecise estimate for the Richardson constant. A modified version of the cube-root plots introduced by Ott and Mann [J. Fluid Mech. 422, 207 (2000)] confirms such convergence. It has been used to yield more precise estimates for Richardson's constant g which decrease with Taylor-scale Reynolds numbers over the range of 140-650. Extrapolation to the large Reynolds number limit gives an asymptotic value for Richardson's constant in the range g =0.55-0.57, depending on the functional form used to make the extrapolation.

Dynamical phase transitions in generalized Kuramoto model with distributed Sakaguchi phase

NASA Astrophysics Data System (ADS)

Banerjee, Amitava

2017-11-01

In this numerical work, we have systematically studied the dynamical phase transitions in the Kuramoto-Sakaguchi model of synchronizing phase oscillators controlled by disorder in the Sakaguchi phases. We derive the numerical steady state phase diagrams for quenched and annealed kinds of disorder in the Sakaguchi parameters, using the conventional order parameter and other such statistical quantities as strength of incoherence and discontinuity measures. We have also considered the correlation profile of the local order parameter fluctuations in the various phases identified. The phase diagrams for quenched disorder are qualitatively much different from those in the global coupling regime. The order of various transitions is confirmed by a study of the distribution of the order parameter and its fourth order Binder’s cumulant across the transition for an ensemble of initial distribution of phases. For the annealed type of disorder, in contrast to the case with quenched disorder, the system is almost insensitive to the amount of disorder. We also elucidate the role of chimeralike states in the synchronizing transition of the system, and study the effect of disorder on these states. Finally, we seek justification of our results from simulations guided by the Ott-Antonsen ansatz.

A New Light Curve and Analysis of the Long Period Eclipsing Binary BF Draconis

NASA Astrophysics Data System (ADS)

Wolf, G. W.; Craig, L. E.; Caffey, J. F.

1999-01-01

The star BF Draconis was found to be an eclipsing binary by Strohmeier, Knigge and Ott (1962) and originally thought to be an Algol-type system with a period of 5.6 days. A spectrographic study by Imbert (1985) showed that the period was actually double this value and that the system consisted of two well-separated, almost-equal F-type stars in elliptical orbit. Diethelm, Wolf and Agerer (1993) later published a preliminary light curve of this system showing minima of unequal depth and width with a displaced secondary, confirming the elliptical orbit but disagreeing with Imbert on the specific orbital parameters. As a part of our long-term program of obtaining improved light curves of double-lined spectroscopic and eclipsing binaries, we have observed BF Draconis for the past four years using the 0.4 meter telescope at the Baker Observatory of Southwest Missouri State University. Complete light curves in the Cousins BVRI passbands have been obtained with our Photometrics CCD system, and a new model and orbital parameters for the binary have been determined using the Wilson-Devinney program. This research has been supported by NSF Grants AST-9315061 and AST-9605822 and NASA Grant NGT5-40060.

Extensive Natural Intraspecific Variation in Stoichiometric (C:N:P) Composition in Two Terrestrial Insect Species

PubMed Central

Bertram, S. M.; Bowen, M.; Kyle, M.; Schade, J. D.

2008-01-01

Heterotrophic organisms must obtain essential elements in sufficient quantities from their food. Because plants naturally exhibit extensive variation in their elemental content, it is important to quantify the within-species stoichiometric variation of consumers. If extensive stoichiometric variation exists, it may help explain consumer variation in life-history strategy and fitness. To date, however, research on stoichiometric variation has focused on interspecific differences and assumed minimal intraspecific differences. Here this assumption is tested. Natural variation is quantified in body stoichiometry of two terrestrial insects: the generalist field cricket, Gryllus texensis Cade and Otte (Orthoptera: Gryllidae) and a specialist curculionid weevil, Sabinia setosa (Le Conte) (Coleoptera: Curculionidae). Both species exhibited extensive intraspecific stoichiometric variation. Cricket body nitrogen content ranged from 8–12% and there was a four-fold difference in body phosphorus content, ranging from 0.32–1.27%. Body size explained half this stoichiometric variation, with larger individuals containing less nitrogen and phosphorus. Weevils exhibited an almost three-fold difference in body phosphorus content, ranging from 0.38–0.97%. Overall, the variation observed within each of these species is comparable to the variation previously observed across almost all terrestrial insect species. PMID:20298114

Bell-Plesset effects in Rayleigh-Taylor instability of finite-thickness spherical and cylindrical shells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Velikovich, A. L.; Schmit, P. F.

Bell-Plesset (BP) effects account for the influence of global convergence or divergence of the fluid flow on the evolution of the interfacial perturbations embedded in the flow. The development of the Rayleigh-Taylor instability in radiation-driven spherical capsules and magnetically-driven cylindrical liners necessarily includes a significant contribution from BP effects due to the time dependence of the radius, velocity, and acceleration of the unstable surfaces or interfaces. An analytical model is presented that, for an ideal incompressible fluid and small perturbation amplitudes, exactly evaluates the BP effects in finite-thickness shells through acceleration and deceleration phases. The time-dependent dispersion equations determining themore » “instantaneous growth rate” are derived. It is demonstrated that by integrating this approximate growth rate over time, one can accurately evaluate the number of perturbation e-foldings during the inward acceleration phase of the implosion. In the limit of small shell thickness, exact thin-shell perturbation equations and approximate thin-shell dispersion equations are obtained, generalizing the earlier results [E. G. Harris, Phys. Fluids 5, 1057 (1962); E. Ott, Phys. Rev. Lett. 29, 1429 (1972); A. B. Bud'ko et al., Phys. Fluids B 2, 1159 (1990)].« less

Bell-Plesset effects in Rayleigh-Taylor instability of finite-thickness spherical and cylindrical shells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Velikovich, A. L.; Schmit, P. F.

Bell-Plesset (BP) effects account for the influence of global convergence or divergence of the fluid flow on the evolution of the interfacial perturbations embedded in the flow. The development of the Rayleigh-Taylor instability in radiation-driven spherical capsules and magnetically-driven cylindrical liners necessarily includes a significant contribution from BP effects due to the time dependence of the radius, velocity, and acceleration of the unstable surfaces or interfaces. An analytical model is presented that, for an ideal incompressible fluid and small perturbation amplitudes, exactly evaluates the BP effects in finite-thickness shells through acceleration and deceleration phases. The time-dependent dispersion equations determining themore » “instantaneous growth rate” are derived. It is demonstrated that by integrating this approximate growth rate over time, one can accurately evaluate the number of perturbation e-foldings during the inward acceleration phase of the implosion. As a result, in the limit of small shell thickness, exact thin-shell perturbationequations and approximate thin-shell dispersion equations are obtained, generalizing the earlier results [E. G. Harris, Phys. Fluids 5, 1057 (1962); E. Ott, Phys. Rev. Lett. 29, 1429 (1972); A. B. Bud'ko et al., Phys. Fluids B 2, 1159 (1990)].« less

Mean-field behavior in coupled oscillators with attractive and repulsive interactions.

PubMed

Hong, Hyunsuk; Strogatz, Steven H

2012-05-01

We consider a variant of the Kuramoto model of coupled oscillators in which both attractive and repulsive pairwise interactions are allowed. The sign of the coupling is assumed to be a characteristic of a given oscillator. Specifically, some oscillators repel all the others, thus favoring an antiphase relationship with them. Other oscillators attract all the others, thus favoring an in-phase relationship. The Ott-Antonsen ansatz is used to derive the exact low-dimensional dynamics governing the system's long-term macroscopic behavior. The resulting analytical predictions agree with simulations of the full system. We explore the effects of changing various parameters, such as the width of the distribution of natural frequencies and the relative strengths and proportions of the positive and negative interactions. For the particular model studied here we find, unexpectedly, that the mixed interactions produce no new effects. The system exhibits conventional mean-field behavior and displays a second-order phase transition like that found in the original Kuramoto model. In contrast to our recent study of a different model with mixed interactions [Phys. Rev. Lett. 106, 054102 (2011)], the π state and traveling-wave state do not appear for the coupling type considered here.

Bell-Plesset effects in Rayleigh-Taylor instability of finite-thickness spherical and cylindrical shells

DOE PAGES

Velikovich, A. L.; Schmit, P. F.

2015-12-28

Bell-Plesset (BP) effects account for the influence of global convergence or divergence of the fluid flow on the evolution of the interfacial perturbations embedded in the flow. The development of the Rayleigh-Taylor instability in radiation-driven spherical capsules and magnetically-driven cylindrical liners necessarily includes a significant contribution from BP effects due to the time dependence of the radius, velocity, and acceleration of the unstable surfaces or interfaces. An analytical model is presented that, for an ideal incompressible fluid and small perturbation amplitudes, exactly evaluates the BP effects in finite-thickness shells through acceleration and deceleration phases. The time-dependent dispersion equations determining themore » “instantaneous growth rate” are derived. It is demonstrated that by integrating this approximate growth rate over time, one can accurately evaluate the number of perturbation e-foldings during the inward acceleration phase of the implosion. As a result, in the limit of small shell thickness, exact thin-shell perturbationequations and approximate thin-shell dispersion equations are obtained, generalizing the earlier results [E. G. Harris, Phys. Fluids 5, 1057 (1962); E. Ott, Phys. Rev. Lett. 29, 1429 (1972); A. B. Bud'ko et al., Phys. Fluids B 2, 1159 (1990)].« less

Bell-Plesset effects in Rayleigh-Taylor instability of finite-thickness spherical and cylindrical shells

NASA Astrophysics Data System (ADS)

Velikovich, A. L.; Schmit, P. F.

2015-12-01

Bell-Plesset (BP) effects account for the influence of global convergence or divergence of the fluid flow on the evolution of the interfacial perturbations embedded in the flow. The development of the Rayleigh-Taylor instability in radiation-driven spherical capsules and magnetically-driven cylindrical liners necessarily includes a significant contribution from BP effects due to the time dependence of the radius, velocity, and acceleration of the unstable surfaces or interfaces. An analytical model is presented that, for an ideal incompressible fluid and small perturbation amplitudes, exactly evaluates the BP effects in finite-thickness shells through acceleration and deceleration phases. The time-dependent dispersion equations determining the "instantaneous growth rate" are derived. It is demonstrated that by integrating this approximate growth rate over time, one can accurately evaluate the number of perturbation e-foldings during the inward acceleration phase of the implosion. In the limit of small shell thickness, exact thin-shell perturbation equations and approximate thin-shell dispersion equations are obtained, generalizing the earlier results [E. G. Harris, Phys. Fluids 5, 1057 (1962); E. Ott, Phys. Rev. Lett. 29, 1429 (1972); A. B. Bud'ko et al., Phys. Fluids B 2, 1159 (1990)].

Climate change and temperate zone insects: the tyranny of thermodynamics meets the world of limited resources.

PubMed

Adamo, Shelley A; Baker, Jillian L; Lovett, Maggie M E; Wilson, Graham

2012-12-01

Climate change will result in warmer temperatures and an increase in the frequency and severity of extreme weather events. Given that higher temperatures increase the reproductive rate of temperate zone insects, insect population growth rates are predicted to increase in the temperate zone in response to climate. This consensus, however, rests on the assumption that food is freely available. However, under conditions of limited food, the reproductive output of the Texan cricket Gryllus texensis (Cade and Otte) was highest at its current normal average temperature and declined with increasing temperature. Moreover, low food availability decreased survival during a simulated heat wave. Therefore, the effects of climate change on this species, and possibly on many others, are likely to hinge on food availability. Extrapolation from our data suggests that G. texensis will show larger yearly fluctuations in population size as climate change continues, and this will also have ecological repercussions. Only those temperate zone insects with a ready supply of food (e.g., agricultural pests) are likely to experience the predicted increase in population growth in response to climate change; food-limited species are likely to experience a population decline.

Simple theory for the dependence of the electrical resistance of the magnetic superconductors TmRh/sub 4/B/sub 4/ and ErRh/sub 4/B/sub 4/ on temperature and field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meijer, H.C.; Andriessen, J.; Postma, H.

1986-04-01

A phenomenological description for the temperature and magnetic field dependence of the electrical resistance R of polycrystalline samples of the reentrant superconductors TmRh/sub 4/B/sub 4/ and ErRh/sub 4/B/sub 4/ is given on the basis of two assumptions: (1) Due to the anisotropic values of the rare-earth ions the critical field of the crystallites depends on the direction of the externally applied field, which leads to an increasing number of normal crystallites with increasing field. For the dependence of the magnetization M on temperature, a molecular field model is used. (2) The bulk resistance R of the sample depends in amore » linear way on the fraction of normal crystallites. There is a qualitative agreement with the experimental results of Hamaker et al. and of Ott et al. It is also shown that an applied field H/sub e/ is equal to the orbital critical field H(/sub c//sub 2/ for the temperature at which R(H/sub e/, T) starts deviating from the resistance of the normal sample.« less

Medical History in the Hellenic Journal of Nuclear Medicine.

PubMed

Otte, Andreas

2017-01-01

The Hellenic Journal of Nuclear Medicine is about to celebrate its 20th anniversary end of 2017. On board of the editorial team since 2003, this journal has influenced me like a good friend over the many past years. From time to time, the journal has published interesting and valuable historical notes. They show that nuclear medicine has a history and that medicine is its basis. They also teach us today, and some of the ancient perspectives and approaches are still valid. The reader of HJNM may be interested in these historical contributions, as they are timeless. Therefore, it was our idea to summarize these in the following pages. Where there is a link to the free article, this is noted. Upon opening all articles, you will find out that these are a book or so of its own. In thanks to the editor-in-chief of the Journal for his continuing support on the historical section. Below we refer to the historical papers of the Journal: History of Nuclear Medicine. Nuclear Medicine and History of Science and Philosophy: Atomic Theory of the Matter. G.N. Sfakianakis, 2001; 4(3); 155-60. Editorial. Pioneers of nuclear medicine, Madame Curie. P.C. Grammaticos. 2004; 7(1); 29-30. http://nuclmed.web.auth.gr/ magazine/eng/jan04/editorial.htm Editor's note. Hippocrates' Oath. The editor. 2004; 7(1); 31. Editorial. Useful known and unknown views of the father of modern medicine, Hippocrates and his teacher Democritus. P. Grammaticos, A. Diamantis. 2008; 11(1): 2-4. http://nuclmed.web.auth.gr/magazine/eng/jan08/2.pdf Special Article. The contribution of Maria Sklodowska-Curie and Pierre Curie to Nuclear and Medical Physics. A hundred and ten years after the discovery of radium. A. Diamantis, E. Magiorkinis, 2008; 11(1): 33-8. http://nuclmed.web.auth.gr/magazine/ eng/jan08/33.pdf Brief Historical Review. Lymphatic system and lymphoscintigraphy. P. Valsamaki. 2009; 12(1): 87-89. http://nuclmed.web. auth.gr/magazine/eng/jan09/89.pdf (In Greek) Historical Review. The philosophic and biological views of the "atomic" philosophers, Leucippus and Democritus. E. Magiorkinis. A. Beloukas, A. Diamantis. 2010; 13(2): 111-117. http://nuclmed.web.auth.gr/magazine/eng/may10/9.pdf Correspondence. Neuroimaging in mild traumatic brain injury and M. Ravel's injury. A. Otte. 2012; 15(1): 76. http://nuclmed. web.auth.gr/magazine/eng/jan12/3.pdf Selected Brief Contributions. The "atomic theory" of Leucippus, and its impact on medicine before Hippocrates. G. Tsoucalas, K. Laios et al. 2013; 16(1): 68-9. http://nuclmed.web.auth.gr/magazine/eng/jan13/72.pdf Selected Brief Contributions. Computed tomography alone reveals the secrets of ancient mummies in medical archaeology. A. Otte, T. Thieme et al. 2013; 16(2): 148-9. http://nuclmed.web.auth.gr/magazine/eng/may13/70.pdf Editorial. The timeless influence of Hippocratic ideas on diet, salicylates and personalized medicine. T.C. Karagiannis. 2014; 17(1): 2-6. http://nuclmed.web.auth.gr/magazine/eng/jan14/1.pdf Historical Article. The physician who first applied radiotherapy, Victor Despeignes, on 1896. M. Sgantzos, G. Tsoucalas et al. 2014; 17(1): 45-6. http://nuclmed.web.auth.gr/magazine/eng/jan14/11.pdf Original Articles. Medical practice applied in the ancient Asclepeion in Kos island. M. Mironidou-Tzouveleki, P.M. Tzitzis. 2014; 17(3): 167-70. http://www.nuclmed.web.auth.gr/magazine/eng/sept14/3.pdf Special Historical Article. How a tertiary medical nuclear medicine department at the Himalayan area in India can be established and function in an exemplary manner. Basic rules revisited. V.K. Dhingra, S. Saini et al. 2015; 18(3): 252-6. http:// nuclmed.web.auth.gr/magazine/eng/sept15/13.pdf Historical and Commentary Note. Johann Sebastian Bach's "Goldberg variations" to treat insomnia from renal lithiasis pain. Sleep research in Nuclear Medicine. A. Otte. 2016; 19(1): 13-4. http://nuclmed.web.auth.gr/magazine/eng/jan16/06.pdf Historical Review. The first medical ethics and deontology in Europe as derived from Greek mythology. M.K. Konstantinidou. 2016; 19(2): 155-8.http://nuclmed.web.auth.gr/magazine/eng/may16/11.pdf Historical-Technical Article. The beginning of using X-rays and the evolution of equipment for the treatment of ocular cancer. K. Laios, M. Zozoglou. 2017; 20(1): Ahead of print. And hopefully many more to follow!

License Compliance Issues For Biopharmaceuticals: Special Challenges For Negotiations Between Companies And Non-Profit Research Institutions.

PubMed

Ponzio, Todd A; Feindt, Hans; Ferguson, Steven

2011-09-01

Biopharmaceuticals are therapeutic products based on biotechnology. They are manufactured by or from living organisms and are the most complex of all commercial medicines to develop, manufacture and qualify for regulatory approval. In recent years biopharmaceuticals have rapidly increased in number and importance with over 400() already marketed in the U.S. and European markets alone. Many companies throughout the world are now ramping up investments in biopharmaceutical R&D and expanding their portfolios through licensing of early-stage biotechnologies from universities and other non-profit research institutions, and there is an increasing number of license agreements for biopharmaceutical product development relative to traditional small molecule drug compounds. This trend will only continue as large numbers of biosimilars and biogenerics enter the market.A primary goal of technology transfer offices associated with publicly-funded, non-profit research institutions is to establish patent protection for inventions deemed to have commercial potential and license them for product development. Such licenses help stimulate economic development and job creation, bring a stream of royalty revenue to the institution and, hopefully, advance the public good or public health by bringing new and useful products to market. In the course of applying for such licenses, a commercial development plan is usually put forth by the license applicant. This plan indicates the path the applicant expects to follow to bring the licensed invention to market. In the case of small molecule drug compounds, there exists a widely-recognized series of clinical development steps, dictated by regulatory requirements, that must be met to bring a new drug to market, such as completion of preclinical toxicology, Phase 1, 2 and 3 testing and product approvals. These steps often become the milestone/benchmark schedule incorporated into license agreements which technology transfer offices use to monitor the licensee's diligence and progress; most exclusive licenses include a commercial development plan, with penalties, financial or even revocation of the license, if the plan is not followed, e.g., the license falls too far behind.This study examines whether developmental milestone schedules based on a small molecule drug development model are useful and realistic in setting expectations for biopharmaceutical product development. We reviewed the monitoring records of all exclusive Public Health Service (PHS) commercial development license agreements for small molecule drugs or therapeutics based on biotechnology (biopharmaceuticals) executed by the National Institutes of Health (NIH) Office of Technology Transfer (OTT) between 2003 and 2009. We found that most biopharmaceutical development license agreements required amending because developmental milestones in the negotiated schedule could not be met by the licensee. This was in stark contrast with license agreements for small molecule chemical compounds which rarely needed changes to their developmental milestone schedules. As commercial development licenses for biopharmaceuticals make up the vast majority of NIH's exclusive license agreements, there is clearly a need to: 1) more closely examine how these benchmark schedules are formed, 2) try to understand the particular risk factors contributing to benchmark schedule non-compliance, and 3) devise alternatives to the current license benchmark schedule structural model. Schedules that properly weigh the most relevant risk factors such as technology classification (e.g., vaccine vs recombinant antibody vs gene therapy), likelihood of unforeseen regulatory issues, and company size/structure may help assure compliance with original license benchmark schedules. This understanding, coupled with a modified approach to the license negotiation process that makes use of a clear and comprehensive term sheet to minimize ambiguities should result in a more realistic benchmark schedule.

License Compliance Issues For Biopharmaceuticals: Special Challenges For Negotiations Between Companies And Non-Profit Research Institutions

PubMed Central

Ponzio, Todd A.; Feindt, Hans; Ferguson, Steven

2011-01-01

Summary Biopharmaceuticals are therapeutic products based on biotechnology. They are manufactured by or from living organisms and are the most complex of all commercial medicines to develop, manufacture and qualify for regulatory approval. In recent years biopharmaceuticals have rapidly increased in number and importance with over 4001 already marketed in the U.S. and European markets alone. Many companies throughout the world are now ramping up investments in biopharmaceutical R&D and expanding their portfolios through licensing of early-stage biotechnologies from universities and other non-profit research institutions, and there is an increasing number of license agreements for biopharmaceutical product development relative to traditional small molecule drug compounds. This trend will only continue as large numbers of biosimilars and biogenerics enter the market. A primary goal of technology transfer offices associated with publicly-funded, non-profit research institutions is to establish patent protection for inventions deemed to have commercial potential and license them for product development. Such licenses help stimulate economic development and job creation, bring a stream of royalty revenue to the institution and, hopefully, advance the public good or public health by bringing new and useful products to market. In the course of applying for such licenses, a commercial development plan is usually put forth by the license applicant. This plan indicates the path the applicant expects to follow to bring the licensed invention to market. In the case of small molecule drug compounds, there exists a widely-recognized series of clinical development steps, dictated by regulatory requirements, that must be met to bring a new drug to market, such as completion of preclinical toxicology, Phase 1, 2 and 3 testing and product approvals. These steps often become the milestone/benchmark schedule incorporated into license agreements which technology transfer offices use to monitor the licensee’s diligence and progress; most exclusive licenses include a commercial development plan, with penalties, financial or even revocation of the license, if the plan is not followed, e.g., the license falls too far behind. This study examines whether developmental milestone schedules based on a small molecule drug development model are useful and realistic in setting expectations for biopharmaceutical product development. We reviewed the monitoring records of all exclusive Public Health Service (PHS) commercial development license agreements for small molecule drugs or therapeutics based on biotechnology (biopharmaceuticals) executed by the National Institutes of Health (NIH) Office of Technology Transfer (OTT) between 2003 and 2009. We found that most biopharmaceutical development license agreements required amending because developmental milestones in the negotiated schedule could not be met by the licensee. This was in stark contrast with license agreements for small molecule chemical compounds which rarely needed changes to their developmental milestone schedules. As commercial development licenses for biopharmaceuticals make up the vast majority of NIH’s exclusive license agreements, there is clearly a need to: 1) more closely examine how these benchmark schedules are formed, 2) try to understand the particular risk factors contributing to benchmark schedule non-compliance, and 3) devise alternatives to the current license benchmark schedule structural model. Schedules that properly weigh the most relevant risk factors such as technology classification (e.g., vaccine vs recombinant antibody vs gene therapy), likelihood of unforeseen regulatory issues, and company size/structure may help assure compliance with original license benchmark schedules. This understanding, coupled with a modified approach to the license negotiation process that makes use of a clear and comprehensive term sheet to minimize ambiguities should result in a more realistic benchmark schedule. PMID:22162900

Postoperative radiotherapy dose requirement in standard combined-modality practice for head and neck squamous cell carcinoma: Analysis of salient surgical and radiotherapy parameters in 2 cohorts.

PubMed

Mohanti, Bidhu K; Thakar, Alok; Kaur, Jaspreet; Bahadur, Sudhir; Malik, Monica; Gandhi, Ajeet K; Bhasker, Suman; Sharma, Atul

2017-09-01

This study compared 2 sequential cohorts to identify the postoperative radiotherapy (PORT) dose requirement for head and neck squamous cell carcinoma (HNSCC). Two distinct PORT dose regimens were prescribed over 11 years; group 1 received 56 Gy or less, and group 2 received 60 Gy or more. The 2D and 3D techniques were used. Two sequential cohorts consisted of 478 patients, with mean and median follow-up for group 1 and 2 as: 37.0 versus 28.5 months and 13.8 versus 13.1 months, respectively. Grades 3-4 mucosal toxicities (11.4% vs 28.3%), hospitalization (3.2% vs 17.4%), and nasogastric feeding (11.9% vs 29.7%) were higher in group 2. The 2-year disease-free survival (DFS) was higher with PORT >60 Gy for the following factors: age ≤ 50 years (P = .041); ≥ 4 positive nodes (P = .029); and overall treatment time (OTT) ≥ 100 days (P = .042). Except for the benefit of doses >60 Gy for limited parameters, a lower PORT dose did not compromise the results and can potentially reduce the morbidities and healthcare costs. © 2017 Wiley Periodicals, Inc.

Can Whole-Body Cryotherapy with Subsequent Kinesiotherapy Procedures in Closed Type Cryogenic Chamber Improve BASDAI, BASFI, and Some Spine Mobility Parameters and Decrease Pain Intensity in Patients with Ankylosing Spondylitis?

PubMed

Stanek, Agata; Cholewka, Armand; Gadula, Jolanta; Drzazga, Zofia; Sieron, Aleksander; Sieron-Stoltny, Karolina

2015-01-01

The present study investigated whether whole-body cryotherapy (WBC) procedures could potentially have more beneficial effects on index of BASDAI and BASFI, pain intensity, and spine mobility parameters: Ott test, modified Schober test, chest expansion in ankylosing spondylitis (AS) patients, than kinesiotherapy procedures used separately. AS patients were exposed to a cycle of WBC procedures lasting 3 minutes a day, with a subsequent 60 minutes of kinesiotherapy or 60 minutes of kinesiotherapy only, for 10 consecutive days excluding weekend. After the completion of the cycle of WBC procedures with subsequent kinesiotherapy in the AS patients, BASDAI index decreased about 40% in comparison with the input value, whereas in the group of patients who received only kinesiotherapy it decreased only about 15% in comparison with the input value. After the completion of the treatment in the WBC group, BASFI index decreased about 30% in comparison with the input value, whereas in the kinesiotherapy group it only decreased about 16% in comparison with the input value. The important conclusion was that, in WBC group with subsequent kinesiotherapy, we observed on average about twice better results than in the group treated only by kinesiotherapy.

Can Whole-Body Cryotherapy with Subsequent Kinesiotherapy Procedures in Closed Type Cryogenic Chamber Improve BASDAI, BASFI, and Some Spine Mobility Parameters and Decrease Pain Intensity in Patients with Ankylosing Spondylitis?

PubMed Central

Stanek, Agata; Cholewka, Armand; Gadula, Jolanta; Drzazga, Zofia; Sieron, Aleksander; Sieron-Stoltny, Karolina

2015-01-01

The present study investigated whether whole-body cryotherapy (WBC) procedures could potentially have more beneficial effects on index of BASDAI and BASFI, pain intensity, and spine mobility parameters: Ott test, modified Schober test, chest expansion in ankylosing spondylitis (AS) patients, than kinesiotherapy procedures used separately. AS patients were exposed to a cycle of WBC procedures lasting 3 minutes a day, with a subsequent 60 minutes of kinesiotherapy or 60 minutes of kinesiotherapy only, for 10 consecutive days excluding weekend. After the completion of the cycle of WBC procedures with subsequent kinesiotherapy in the AS patients, BASDAI index decreased about 40% in comparison with the input value, whereas in the group of patients who received only kinesiotherapy it decreased only about 15% in comparison with the input value. After the completion of the treatment in the WBC group, BASFI index decreased about 30% in comparison with the input value, whereas in the kinesiotherapy group it only decreased about 16% in comparison with the input value. The important conclusion was that, in WBC group with subsequent kinesiotherapy, we observed on average about twice better results than in the group treated only by kinesiotherapy. PMID:26273618

Homeosis and beyond. What is the function of the Hox genes?

PubMed

Deutsch, Jean S

2010-01-01

What is the function of the Hox genes? At first glance, it is a curious question. Indeed, the answer seems so obvious that several authors have spoken of 'the Hox function' about some of the Hox genes, namely Hox3/zen and Hox6/ftz that seem to have lost it during the evolution of Arthropods. What these authors meant is that these genes have lost their 'homeotic' function. Indeed, 'homeotic' refers to a functional property that is so often associated with the Hox genes. However, the word 'Hox' should not be used to refer to a function, but to a group of genes. The above examples of Hox3/zen (see Schmitt-Ott's chapter, this book) and Hox6/ftz show that the homeotic function may be not so tightly linked to the Hox genes. Reversely, many genes, not belonging to the Hox group, do present a homeotic function. In the present chapter, I will first give a definition of the Hox genes. I will then ask what is the 'function' of a gene, examining its various meanings at different levels of biological organization. I will review and revisit the relation between the Hox genes and homeosis. I will suggest that their morphological homeotic function has been secondarily derived during the evolution of the Bilateria.

The Balloon-Based Manometry Evaluation of Swallowing in Patients with Amyotrophic Lateral Sclerosis

PubMed Central

Tomik, Jerzy; Tomik, Barbara; Gajec, Sebastian; Ceranowicz, Piotr; Pihut, Małgorzata; Olszanecki, Rafał; Stręk, Paweł; Składzień, Jacek

2017-01-01

The aim of the study was to analyse the disturbances of the oro-pharyngeal swallowing phase of dysphagia in amyotrophic lateral sclerosis (ALS) patients with the use of specific manometric measurements and to evaluate their plausible association with the duration of the disease. Seventeen patients with ALS were evaluated with manometric examinations of the oral and pharyngeal part of the gastrointestinal tract. Tests were carried out by using the oesophageal balloon-based method with four balloon transducers located 5 cm away from each other. The following manometric parameters were analysed: the base of tongue contraction (BTC) and the upper oesophageal sphincter pressure (UESP), and the hypopharyngeal suction pump (HSP) as well as the oro-pharyngeal, pharyngeal and hypopharyngeal transit time and average pharyngeal bolus velocity (oropharyngeal transit time (OTT), pharyngeal transit time (PTT), hypopharyngeal transit time (HTT) and average pharyngeal bolus velocity (APBV), respectively). Manomatric examinations during swallowing in patients with ALS showed significant weakness of BTC, a decrease of HSP and a decrease of the velocity of bolus transit inside the pharynx which were particularly marked between the first and the third examination. Manometric examinations of the oro-pharyngeal part of the gastrointestinal tract are useful and supportive methods in the analysis of swallowing disturbances in ALS patients. PMID:28346382

Circinaria gyrosa, a new astrobiological model system for studying the effects of heavy ion irradiation

NASA Astrophysics Data System (ADS)

Martín, María Luisa; Moeller, Ralf; De la Torre Noetzel, Rosa; Raguse, M. Marina

Up to date, most astrobiological experiments performed on space have been carried out on board of Earth-orbiting spacecrafts (e.g., Foton satellites), or on board of human-tended spacecrafts, (space shuttles and space stations). Organisms included in these experiments have been exposed to harsh space conditions: vacuum, doses of UV and ionizing radiation as well as extreme temperature fluctuations. Space radiation that arrived on these organisms is related with different sources: (e.g. solar particle events, galactic cosmic rays and electromagnetic radiation) [1]. More information on biological effects of cosmic radiation is needed to understand the possible risks for biological systems exposed to space conditions and to broaden our knowledge on the limits of terrestrial life. This study is focused on Circinaria gyrosa (from Aspicilia fruticulosa, ren. see Sohrabi, M., 2012), a vagrant lichen species collected at the steppic highlands of Central Spain. C. gyrosa. has been previously used in various space experiments, e.g., LITHOPANSPERMIA experiment, BIOPAN-6, FOTON M3, 2007, and in ground-based laboratory studies [2]. For example, after intensive UV-C exposure (7.2 x 107J/m2), C. gyrosa showed the highest PS-II activity of all lichens species tested [3]. Based on this high resistance to UV radiation C. gyrosa has been included in the next EXPOSE-R2 ISS experiment called “BIOMEX” (Biology and Mars-Experiment), in which different biological systems will be exposed to space and Martian conditions for nearly one and a half year. Here, we will present our first results of C.gyrosa, which have been obtained in frame of the STARLIFE project, an intercomparison project testing the effects of space-relevant ionizing radiation, i.e., heavy ions and X-rays, on different astrobiological model systems. For C. gyrosa we tested the organism metabolism through pulse amplitude modulated (PAM) fluorescence analysis prior and after the each irradiation experiment. This new data provide further evidence that lichens are suitable organisms to experimentally verify the potential of lichens in a Lithopanspermia scenario, as indicated by Horneck et al. (2008) [4] References [1] L. R. Dartnell. Ionizing radiation and life Astrobiology 11(6): 551-582 (2011) [2] R. de la Torre, L. G. Sancho, G. Horneck, A. de los Rios, J. Wierzchos, K. Olsson-Francis, C. S. Cockell, P. Rettberg, T. Berger, J. P. de Vera, S. Ott, J. Martinez Frias. P. González Melendi, M. M. Lucas, M. Reina, A. Pintado and R. Demets. Survival of lichens and bacteria exposed to outer space conditions. Results of the Lithopanspermia experiments. Icarus 208: 735-748 (2010) [3] F. J. Sánchez, E. Mateo-Martí, J. Raggio, J. Meeßen, J. Martínez-Frías, L. G .Sancho, S. Ott and R. de la Torre. The resistance of the lichen Circinaria gyrosa (nom. provis.) towards simulated Mars conditions - a model test for the survival capacity of an eukaryotic extremophile. Planetary and Space Science. 72 (1): 102-110 (2012) [4] Horneck, G., Klaus, D.M., and R. L. Mancinelli. Space microbiology. Microbiology and Molecular Biology Reviews: 74(1):121-156 (2010)

Thin layer model for nonlinear evolution of the Rayleigh-Taylor instability

NASA Astrophysics Data System (ADS)

Zhao, K. G.; Wang, L. F.; Xue, C.; Ye, W. H.; Wu, J. F.; Ding, Y. K.; Zhang, W. Y.

2018-03-01

On the basis of the thin layer approximation [Ott, Phys. Rev. Lett. 29, 1429 (1972)], a revised thin layer model for incompressible Rayleigh-Taylor instability has been developed to describe the deformation and nonlinear evolution of the perturbed interface. The differential equations for motion are obtained by analyzing the forces (the gravity and pressure difference) of fluid elements (i.e., Newton's second law). The positions of the perturbed interface are obtained from the numerical solution of the motion equations. For the case of vacuum on both sides of the layer, the positions of the upper and lower interfaces obtained from the revised thin layer approximation agree with that from the weakly nonlinear (WN) model of a finite-thickness fluid layer [Wang et al., Phys. Plasmas 21, 122710 (2014)]. For the case considering the fluids on both sides of the layer, the bubble-spike amplitude from the revised thin layer model agrees with that from the WN model [Wang et al., Phys. Plasmas 17, 052305 (2010)] and the expanded Layzer's theory [Goncharov, Phys. Rev. Lett. 88, 134502 (2002)] in the early nonlinear growth regime. Note that the revised thin layer model can be applied to investigate the perturbation growth at arbitrary Atwood numbers. In addition, the large deformation (the large perturbed amplitude and the arbitrary perturbed distributions) in the initial stage can also be described by the present model.

Decision making with environmental indices

USGS Publications Warehouse

Hoag, Dana L.; Ascough, James C.; Keske-Handley, C.; Koontz, Lynne; Burk, A.R.

2005-01-01

Since Ott's seminal book on environmental indices (1978), the use of indices has expanded into several natural resource disciplines, including ecological studies, environmental policymaking, and agricultural economics. However, despite their increasing use in natural resource disciplines, researchers and public decision makers continue to express concern about validity of these instruments to capture and communicate multidimensional, and sometimes disparate, characteristics of research data and stakeholder interests. Our purpose is to demonstrate how useful indices can be for communicating environmental information to decision makers. We discuss how environmental indices have evolved over four stages: 1) simple; 2) compound multicriteria; 3) the impact matrix and 4) disparate stakeholder management. We provide examples of simple and compound indices that were used by policy decision makers. We then build a framework, called an Impact Matrix (IM), that comprehensively accounts for multiple indices but lets the user decide how to integrate them. The IM was shaped from the concept of a financial risk payoff matrix and applied to ecosystem risk. While the IM offers flexibility, it does not address stakeholder preferences about which index to use. Therefore, the last phase in our evolutionary ladder includes stakeholder indices to specifically address disparate stakeholder preferences. Finally, we assert that an environmental index has the potential to increase resource efficiency, since the number of decision making resources may be reduced, and hence improve upon resource productivity

Structural Characteristics of Nocturnal Mesoscale Convective Systems in the U.S. Great Plains as Observed During the PECAN Field Campaign

NASA Astrophysics Data System (ADS)

Bodine, D. J.; Dougherty, E.; Rasmussen, K. L.; Torres, A. D.

2015-12-01

During the summer in the U.S. Great Plains, some of the heaviest precipitation falls from large thunderstorm complexes known as Mesoscale Convective Systems (MCSs). These frequently occurring MCSs are often nocturnal in nature, so the dynamics associated with these systems are more elusive than those in the daytime. The Plains Elevated Convection at Night (PECAN) field campaign was launched over a 7-week period as an endeavor to better understand nocturnal MCSs occurring in the Great Plains. PECAN featured a dense array of ground-based and airborne instruments to observe nocturnal MCS, including dual-polarization radars at multiple frequencies, mobile mesonets, and sounding units. Our role in PECAN involved deploying Ott Parsivel disdrometers to gain information on drop size distributions (DSDs) and fall speeds. Analysis of disdrometer data in conjunction with radar data presented using Contour Frequency by Altitude Diagrams (CFADs) and high-resolution radiosonde data allows for a structural comparison of PECAN MCS cases to previously identified MCS archetypes. Novel insights into the structural evolution of nocturnal MCSs in relation to their synoptic, mesoscale, and thermodynamic environments are presented, using data collected from dense and numerous observation platforms. Understanding the environmental conditions that result in different nocturnal MCS configurations is useful for gaining insight into precipitation distributions and potential severe weather and flooding hazards in the Great Plains.

Using raindrop size distributions from different types of disdrometer to establish weather radar algorithms

NASA Astrophysics Data System (ADS)

Baldini, Luca; Adirosi, Elisa; Roberto, Nicoletta; Vulpiani, Gianfranco; Russo, Fabio; Napolitano, Francesco

2015-04-01

Radar precipitation retrieval uses several relationships that parameterize precipitation properties (like rainfall rate and liquid water content and attenuation (in case of radars at attenuated frequencies such as those at C- and X- band) as a function of combinations of radar measurements. The uncertainty in such relations highly affects the uncertainty precipitation and attenuation estimates. A commonly used method to derive such relationships is to apply regression methods to precipitation measurements and radar observables simulated from datasets of drop size distributions (DSD) using microphysical and electromagnetic assumptions. DSD datasets are determined both by theoretical considerations (i.e. based on the assumption that the radar always samples raindrops whose sizes follow a gamma distribution) or from experimental measurements collected throughout the years by disdrometers. In principle, using long-term disdrometer measurements provide parameterizations more representative of a specific climatology. However, instrumental errors, specific of a disdrometer, can affect the results. In this study, different weather radar algorithms resulting from DSDs collected by diverse types of disdrometers, namely 2D video disdrometer, first and second generation of OTT Parsivel laser disdrometer, and Thies Clima laser disdrometer, in the area of Rome (Italy) are presented and discussed to establish at what extent dual-polarization radar algorithms derived from experimental DSD datasets are influenced by the different error structure of the different type of disdrometers used to collect the data.

Bell-Plesset effects in Rayleigh-Taylor instability of finite-thickness spherical and cylindrical shells

NASA Astrophysics Data System (ADS)

Velikovich, A. L.; Schmit, P. F.

2015-11-01

Bell-Plesset effects accounting for the time dependence of the radius, velocity and acceleration of the Rayleigh-Taylor-unstable surface are ubiquitous in the instability of spherical laser targets and magnetically driven cylindrical liners. We present an analytical model that, for an ideal incompressible fluid and small perturbation amplitudes, exactly accounts for the Bell-Plesset effects in finite-thickness targets and liners through acceleration and deceleration phases. We derive the time-dependent dispersion equations determining the ``instantaneous growth rate'' and demonstrate that by integrating this growth rate over time (the WKB approximation) we accurately evaluate the number of perturbation e-foldings during the acceleration phase. In the limit of the small target/liner thickness, we obtain the exact thin-shell perturbation equations and approximate thin-shell dispersion relations, generalizing the earlier results of Harris (1962), Ott (1972) and Bud'ko et al. (1989). This research was supported by the US DOE/NNSA (A.L.V.), and in part by appointment to the Sandia National Laboratories Truman Fellowship in National Security Science and Engineering (P.F.S.), which is part of the Laboratory Directed Research and Development (LDRD) Program, Project No. 165746, and sponsored by Sandia Corporation (a wholly owned subsidiary of Lockheed Martin Corporation) as Operator of Sandia National Laboratories under its U.S. Department of Energy Contract No. DE-AC04-94AL85000.

Thin Shell Model for NIF capsule stagnation studies

NASA Astrophysics Data System (ADS)

Hammer, J. H.; Buchoff, M.; Brandon, S.; Field, J. E.; Gaffney, J.; Kritcher, A.; Nora, R. C.; Peterson, J. L.; Spears, B.; Springer, P. T.

2015-11-01

We adapt the thin shell model of Ott et al. to asymmetric ICF capsule implosions on NIF. Through much of an implosion, the shell aspect ratio is large so the thin shell approximation is well satisfied. Asymmetric pressure drive is applied using an analytic form for ablation pressure as a function of the x-ray flux, as well as time-dependent 3D drive asymmetry from hohlraum calculations. Since deviations from a sphere are small through peak velocity, we linearize the equations, decompose them by spherical harmonics and solve ODE's for the coefficients. The model gives the shell position, velocity and areal mass variations at the time of peak velocity, near 250 microns radius. The variables are used to initialize 3D rad-hydro calculations with the HYDRA and ARES codes. At link time the cold fuel shell and ablator are each characterized by a density, adiabat and mass. The thickness, position and velocity of each point are taken from the thin shell model. The interior of the shell is filled with a uniform gas density and temperature consistent with the 3/2PV energy found from 1D rad-hydro calculations. 3D linked simulations compare favorably with integrated simulations of the entire implosion. Through generating synthetic diagnostic data, the model offers a method for quickly testing hypothetical sources of asymmetry and comparing with experiment. Prepared by LLNL under Contract DE-AC52-07NA27344.

Are Bred Vectors The Same As Lyapunov Vectors?

NASA Astrophysics Data System (ADS)

Kalnay, E.; Corazza, M.; Cai, M.

Regional loss of predictability is an indication of the instability of the underlying flow, where small errors in the initial conditions (or imperfections in the model) grow to large amplitudes in finite times. The stability properties of evolving flows have been studied using Lyapunov vectors (e.g., Alligood et al, 1996, Ott, 1993, Kalnay, 2002), singular vectors (e.g., Lorenz, 1965, Farrell, 1988, Molteni and Palmer, 1993), and, more recently, with bred vectors (e.g., Szunyogh et al, 1997, Cai et al, 2001). Bred vectors (BVs) are, by construction, closely related to Lyapunov vectors (LVs). In fact, after an infinitely long breeding time, and with the use of infinitesimal ampli- tudes, bred vectors are identical to leading Lyapunov vectors. In practical applications, however, bred vectors are different from Lyapunov vectors in two important ways: a) bred vectors are never globally orthogonalized and are intrinsically local in space and time, and b) they are finite-amplitude, finite-time vectors. These two differences are very significant in a dynamical system whose size is very large. For example, the at- mosphere is large enough to have "room" for several synoptic scale instabilities (e.g., storms) to develop independently in different regions (say, North America and Aus- tralia), and it is complex enough to have several different possible types of instabilities (such as barotropic, baroclinic, convective, and even Brownian motion). Bred vectors share some of their properties with leading LVs (Corazza et al, 2001a, 2001b, Toth and Kalnay, 1993, 1997, Cai et al, 2001). For example, 1) Bred vectors are independent of the norm used to define the size of the perturba- tion. Corazza et al. (2001) showed that bred vectors obtained using a potential enstro- phy norm were indistinguishable from bred vectors obtained using a streamfunction squared norm, in contrast with singular vectors. 2) Bred vectors are independent of the length of the rescaling period as long as the perturbations remain approximately linear (for example, for atmospheric models the interval for rescaling could be varied between a single time step and 1 day without affecting qualitatively the characteristics of the bred vectors. However, the finite-amplitude, finite-time, and lack of orthogonalization of the BVs introduces important differences with LVs: 1) In regions that undergo strong instabilities, the bred vectors tend to be locally domi- 1 nated by simple, low-dimensional structures. Patil et al (2001) showed that the BV-dim (appendix) gives a good estimate of the number of dominant directions (shapes) of the local k bred vectors. For example, if half of them are aligned in one direction, and half in a different direction, the BV-dim is about two. If the majority of the bred vectors are aligned predominantly in one direction and only a few are aligned in a second direction, then the BV-dim is between 1 and 2. Patil et al., (2001) showed that the regions with low dimensionality cover about 20% of the atmosphere. They also found that these low-dimensionality regions have a very well defined vertical structure, and a typical lifetime of 3-7 days. The low dimensionality identifies regions where the in- stability of the basic flow has manifested itself in a low number of preferred directions of perturbation growth. 2) Using a Quasi-Geostrophic simulation system of data assimilation developed by Morss (1999), Corazza et al (2001a, b) found that bred vectors have structures that closely resemble the background (short forecasts used as first guess) errors, which in turn dominate the local analysis errors. This is especially true in regions of low dimensionality, which is not surprising if these are unstable regions where errors grow in preferred shapes. 3) The number of bred vectors needed to represent the unstable subspace in the QG system is small (about 6-10). This was shown by computing the local BV-dim as a function of the number of independent bred vectors. Convergence in the local dimen- sion starts to occur at about 6 BVs, and is essentially complete when the number of vectors is about 10-15 (Corazza et al, 2001a). This should be contrasted with the re- sults of Snyder and Joly (1998) and Palmer et al (1998) who showed that hundreds of Lyapunov vectors with positive Lyapunov exponents are needed to represent the attractor of the system in quasi-geostrophic models. 4) Since only a few bred vectors are needed, and background errors project strongly in the subspace of bred vectors, Corazza et al (2001b) were able to develop cost-efficient methods to improve the 3D-Var data assimilation by adding to the background error covariance terms proportional to the outer product of the bred vectors, thus represent- ing the "errors of the day". This approach led to a reduction of analysis error variance of about 40% at very low cost. 5) The fact that BVs have finite amplitude provides a natural way to filter out instabil- ities present in the system that have fast growth, but saturate nonlinearly at such small amplitudes that they are irrelevant for ensemble perturbations. As shown by Lorenz (1996) Lyapunov vectors (and singular vectors) of models including these physical phenomena would be dominated by the fast but small amplitude instabilities, unless they are explicitly excluded from the linearized models. Bred vectors, on the other 2 hand, through the choice of an appropriate size for the perturbation, provide a natural filter based on nonlinear saturation of fast but irrelevant instabilities. 6) Every bred vector is qualitatively similar to the *leading* LV. LVs beyond the leading LV are obtained by orthogonalization after each time step with respect to the previous LVs subspace. The orthogonalization requires the introduction of a norm. With an enstrophy norm, the successive LVs have larger and larger horizontal scales, and a choice of a stream function norm would lead to successively smaller scales in the LVs. Beyond the first few LVs, there is little qualitative similarity between the background errors and the LVs. In summary, in a system like the atmosphere with enough physical space for several independent local instabilities, BVs and LVs share some properties but they also have significant differences. BV are finite-amplitude, finite-time, and because they are not globally orthogonalized, they have local properties in space. Bred vectors are akin to the leading LV, but bred vectors derived from different arbitrary initial perturba- tions remain distinct from each other, instead of collapsing into a single leading vec- tor, presumably because the nonlinear terms and physical parameterizations introduce sufficient stochastic forcing to avoid such convergence. As a result, there is no need for global orthogonalization, and the number of bred vectors required to describe the natural instabilities in an atmospheric system (from a local point of view) is much smaller than the number of Lyapunov vectors with positive Lyapunov exponents. The BVs are independent of the norm, whereas the LVs beyond the first one do depend on the choice of norm: for example, they become larger in scale with a vorticity norm, and smaller with a stream function norm. These properties of BVs result in significant advantages for data assimilation and en- semble forecasting for the atmosphere. Errors in the analysis have structures very similar to bred vectors, and it is found that they project very strongly on the subspace of a few bred vectors. This is not true for either Lyapunov vectors beyond the lead- ing LVs, or for singular vectors unless they are constructed with a norm based on the analysis error covariance matrix (or a bred vector covariance). The similarity between bred vectors and analysis errors leads to the ability to include "errors of the day" in the background error covariance and a significant improvement of the analysis beyond 3D-Var at a very low cost (Corazza, 2001b). References Alligood K. T., T. D. Sauer and J. A. Yorke, 1996: Chaos: an introduction to dynamical systems. Springer-Verlag, New York. Buizza R., J. Tribbia, F. Molteni and T. Palmer, 1993: Computation of optimal unstable 3 structures for numerical weather prediction models. Tellus, 45A, 388-407. Cai, M., E. Kalnay and Z. Toth, 2001: Potential impact of bred vectors on ensemble forecasting and data assimilation in the Zebiak-Cane model. Submitted to J of Climate. Corazza, M., E. Kalnay, D. J. Patil, R. Morss, M. Cai, I. Szunyogh, B. R. Hunt, E. Ott and J. Yorke, 2001: Use of the breeding technique to determine the structure of the "errors of the day". Submitted to Nonlinear Processes in Geophysics. Corazza, M., E. Kalnay, DJ Patil, E. Ott, J. Yorke, I Szunyogh and M. Cai, 2001: Use of the breeding technique in the estimation of the background error covariance matrix for a quasigeostrophic model. AMS Symposium on Observations, Data Assimilation and Predictability, Preprints volume, Orlando, FA, 14-17 January 2002. Farrell, B., 1988: Small error dynamics and the predictability of atmospheric flow, J. Atmos. Sciences, 45, 163-172. Kalnay, E 2002: Atmospheric modeling, data assimilation and predictability. Chapter 6. Cambridge University Press, UK. In press. Kalnay E and Z Toth 1994: Removing growing errors in the analysis. Preprints, Tenth Conference on Numerical Weather Prediction, pp 212-215. Amer. Meteor. Soc., July 18-22, 1994. Lorenz, E.N., 1965: A study of the predictability of a 28-variable atmospheric model. Tellus, 21, 289-307. Lorenz, E.N., 1996: Predictability- A problem partly solved. Proceedings of the ECMWF Seminar on Predictability, Reading, England, Vol. 1 1-18. Molteni F. and TN Palmer, 1993: Predictability and finite-time instability of the north- ern winter circulation. Q. J. Roy. Meteorol. Soc. 119, 269-298. Morss, R.E.: 1999: Adaptive observations: Idealized sampling strategies for improving numerical weather prediction. Ph.D. Thesis, Massachussetts Institute of Technology, 225pp. Ott, E., 1993: Chaos in Dynamical Systems. Cambridge University Press. New York. Palmer, TN, R. Gelaro, J. Barkmeijer and R. Buizza, 1998: Singular vectors, metrics and adaptive observations. J. Atmos Sciences, 55, 633-653. Patil, DJ, BR Hunt, E Kalnay, J. Yorke, and E. Ott, 2001: Local low dimensionality of atmospheric dynamics. Phys. Rev. Lett., 86, 5878. Patil, DJ, I. Szunyogh, BR Hunt, E Kalnay, E Ott, and J. Yorke, 2001: Using large 4 member ensembles to isolate local low dimensionality of atmospheric dynamics. AMS Symposium on Observations, Data Assimilation and Predictability, Preprints volume, Orlando, FA, 14-17 January 2002. Snyder, C. and A. Joly, 1998: Development of perturbations within growing baroclinic waves. Q. J. Roy. Meteor. Soc., 124, pp 1961. Szunyogh, I, E. Kalnay and Z. Toth, 1997: A comparison of Lyapunov and Singular vectors in a low resolution GCM. Tellus, 49A, 200-227. Toth, Z and E Kalnay 1993: Ensemble forecasting at NMC - the generation of pertur- bations. Bull. Amer. Meteorol. Soc., 74, 2317-2330. Toth, Z and E Kalnay 1997: Ensemble forecasting at NCEP and the breeding method. Mon Wea Rev, 125, 3297-3319. * Corresponding author address: Eugenia Kalnay, Meteorology Depart- ment, University of Maryland, College Park, MD 20742-2425, USA; email: ekalnay@atmos.umd.edu Appendix: BV-dimension Patil et al., (2001) defined local bred vectors around a point in the 3-dimensional grid of the model by taking the 24 closest horizontal neighbors. If there are k bred vectors available, and N model variables for each grid point, the k local bred vectors form the columns of a 25Nxk matrix B. The kxk covariance matrix is C=B^T B. Its eigen- values are positive, and its eigenvectors v(i) are the singular vectors of the local bred vector subspace. The Bred Vector dimension (BV-dim) measures the local effective dimension: BV-dim[s,s,...,s(k)]={SUM[s(i)]}^2/SUM[s(i)]^2 where s(i) are the square roots of the eigenvalues of the covariance matrix. 5

External quality assurance project report for the National Atmospheric Deposition Program’s National Trends Network and Mercury Deposition Network, 2015–16

USGS Publications Warehouse

Wetherbee, Gregory A.; Martin, RoseAnn

2018-06-29

The U.S. Geological Survey Precipitation Chemistry Quality Assurance project operated five distinct programs to provide external quality assurance monitoring for the National Atmospheric Deposition Program’s (NADP) National Trends Network and Mercury Deposition Network during 2015–16. The National Trends Network programs include (1) a field audit program to evaluate sample contamination and stability, (2) an interlaboratory comparison program to evaluate analytical laboratory performance, and (3) a colocated sampler program to evaluate bias and variability attributed to automated precipitation samplers. The Mercury Deposition Network programs include the (4) system blank program and (5) an interlaboratory comparison program. The results indicate that NADP data continue to be of sufficient quality for the analysis of spatial distributions and time trends for chemical constituents in wet deposition.The field audit program results indicate increased sample contamination for calcium, magnesium, and potassium relative to 2010 levels, and slight fluctuation in sodium contamination. Nitrate contamination levels dropped slightly during 2014–16, and chloride contamination leveled off between 2007 and 2016. Sulfate contamination is similar to the 2000 level. Hydrogen ion contamination has steadily decreased since 2012. Losses of ammonium and nitrate resulting from potential sample instability were negligible.The NADP Central Analytical Laboratory produced interlaboratory comparison results with low bias and variability compared to other domestic and international laboratories that support atmospheric deposition monitoring. Significant absolute bias above the magnitudes of the detection limits was observed for nitrate and sulfate concentrations, but no analyte determinations exceeded the detection limits for blanks.Colocated sampler program results from dissimilar colocated collectors indicate that the retrofit of the National Trends Network with N-CON Systems Company, Inc. precipitation collectors could cause substantial shifts in NADP annual deposition (concentration multiplied by depth) values. Median weekly relative percent differences for analyte concentrations ranged from -4 to +76 percent for cations, from 5 to 6 percent for ammonium, from +14 to +25 percent for anions, and from -21 to +8 percent for hydrogen ion contamination. By comparison, weekly absolute concentration differences for paired identical N-CON Systems Company, Inc., collectors ranged from 4–22 percent for cations; 2–9 percent for anions; 4–5 percent for ammonium; and 13–14 percent for hydrogen ion contamination. The N-CON Systems Company, Inc. collector caught more precipitation than the Aerochem Metrics Model 301 collector (ACM) at the WA99/99WA sites, but it typically caught slightly less precipitation than the ACM at ND11/11ND, sites which receive more wind and snow than WA99/99WA.Paired, identical OTT Pluvio-2 and ETI Noah IV precipitation gages were operated at the same sites. Median absolute percent differences for daily measured precipitation depths ranged from 0 to 7 percent. Annual absolute differences ranged from 0.08 percent (ETI Noah IV precipitation gages) to 11 percent (OTT Pluvio-2 precipitation gages).The Mercury Deposition Network programs include the system blank program and an interlaboratory comparison program. System blank results indicate that maximum total mercury contamination concentrations in samples were less than the third percentile of all Mercury Deposition Network sample concentrations (1.098 nanograms per liter; ng/L). The Mercury Analytical Laboratory produced chemical concentration results with low bias and variability compared with other domestic and international laboratories that support atmospheric-deposition monitoring. The laboratory’s performance results indicate a +1-ng/L shift in bias between 2015 (-0.4 ng/L) and 2016 (+0.5 ng/L).

Solar Noble Gases in Polymict Ureilites and an Update on Ureilite Noble Gas Data

NASA Astrophysics Data System (ADS)

Ott, U.; Lohr, H. P.; Begemann, F.

1993-07-01

Ureilites are one of the least understood classes of meteorites; they show signs of being processed, but also appear to be primitive, with abundant carbon and trapped noble gases [1-6]. We have now begun to analyze a number of recently recovered specimens: one from the Saharan desert (Acfer 277) amd five from the Antarctic (LEW 85328, LEW 85440, EET 87720, FRO 90036, and FRO 90054). Analyses of Acfer 277, LEW 85328, and EET 87720 are complete (Table 1). Solar noble gases are present in polymict EET 87720, as shown by the three- isotope plot of Fig. 1. There, in contrast to the bulk data point for Acfer 277, data points for EET 87720 deviate from a mixing line between "typical" spallation Ne (as approximated here by the spallation-dominated 1800 degrees C step for EET 87720) and Ne-U [7] toward higher ^20Ne/^22Ne. A line fitted to the EET 87720 data points passes slightly below Ne-B [8]. The situation is similar for sample F1 from polymict EET 83309 [9], which is shown for comparison. Additional support for the presence of solar gases arises from the abundance of ^4He (~9 x 10^-5 cm^3 STP/g in EET 87720-F1, corrected for spallogenic contributions), which in both cases is far higher than in other ureilite bulk samples [6,10]. Also, in the ratio of spallation-corrected ^4He to trapped ^36Ar, these two polymict ureilites clearly stand out. Helium-4/argon-36 ratios in EET 87720-F1 and EET 83309-F1 are ~20 and ~28 respectively, at least 1 order of magnitude higher than in bulk monomict ureilites and 2 orders of magnitude higher than what appears typical of ureilite diamonds [6]. Nilpena, another polymict ureilite [11], also has a ^4He/^36Ar ratio (2.1 in Nilpena II-1 [7]) higher than all monomict ureilites but one (Dingo Pup Donga), indicating the presence of solar noble gases (in variable contents) as a possible general feature of polymict ureilites, similar to the presence in them of nitrogen with high delta(^15N/^14N) [12]. Monomict LEW 85328 has a very high (^22Ne/^21Ne)(sub)c ratio of the cosmogenic component, indicative of irradiation under very low shielding conditions, but otherwise abundances and abundance ratios for the momomict ureilites LEW 85328 and Acfer 277 appear quite "ordinary" when compared to other monomict ureilites [6,10]. References: [1] Wasson J. T. et al. (1976) GCA, 40, 1449-1458. [2] Berkley J. L. et al. (1980) GCA, 44, 1579-1597. [3] Takeda H. (1989) EPSL, 93, 181- 194. [4] Warren P. H. and Kallemeyn G. W. (1989) Meteoritics, 24, 233-246. [5] Clayton R. N. and Mayeda T. K. (1988) GCA, 52, 1313-1318. [6] Gobel R. et al. (1978) JGR, 83, 855-867. [7] Ott U. et al. (1984) Meteoritics, 19, 287-288. [8] Black D. C. (1972) GCA, 36, 347-375. [9] Ott U. et al. (1990) Meteoritics, 25, 396. [10] Schultz L. and Kruse H. (1989) Meteoritics, 24, 155-172. [11] Jaques A. L. and Fitzgerald M. J. (1982) GCA, 46, 893-900. [12] Grady M. M. and Pillinger C. T. (1988) Nature, 331, 321-323. Table 1, which appears here in the hard copy, shows noble gases in monomict ureilites Acfer 277 and LEW 85328 and polymict ureilite EET 87720. Fig. 1 appears here in the hard copy.

The Microwave Spectroscopy of Aminoacetonitrile in the Vibrational Excited States 2

NASA Astrophysics Data System (ADS)

Fujita, Chiho; Higurashi, Haruka; Ozeki, Hiroyuki; Kobayashi, Kaori

2016-06-01

Aminoacetonitrile (NH_2CH_2CN) is a potential precursor of the simplest amino acid, glycine in the interstellar space and was detected toward SgrB2(N). We have extended measurements up to 1.3 THz so that the strongest transitions that may be found in the terahertz region should be covered. Aminoacetonitrile has a few low-lying vibrational excited states and indeed the pure rotational transitions in these vibrational excited states were found. The pure rotational transitions in six vibrational excited states in the 80-180 GHz range have been assigned and centrifugal distortion constants up to the sextic terms were determined. Based on spectral intensities and the vibrational information from Bak et al., They were assigned to the 3 low-lying fundamentals, 1 overtone and 2 combination bands. In the submillimeter wavelength region, perturbations were recognized and some of the lines were off by more than a few MHz. At this moment, these perturbed transitions are not included in our analysis. A. Belloche, K. M. Menten, C. Comito, H. S. P. Müller, P. Schilke, J. Ott, S. Thorwirth, and C. Hieret, 2008, Astronom. & Astrophys. 482, 179 (2008). Y. Motoki, Y. Tsunoda, H. Ozeki, and K. Kobayashi, Astrophys. J. Suppl. Ser. 209, 23 (2013). B. Bak, E. L. Hansen, F. M. Nicolaisen, and O. F. Nielsen, Can. J. Phys. 53, 2183 (1975) C. Fujita, H. Ozeki, and K. Kobayashi, 70th International Symposium on Molecular Spectroscopy (2015), MH14.

A High-resolution Study of Presupernova Core Structure

NASA Astrophysics Data System (ADS)

Sukhbold, Tuguldur; Woosley, S. E.; Heger, Alexander

2018-06-01

The density structure surrounding the iron core of a massive star when it dies is known to have a major effect on whether or not the star explodes. Here we repeat previous surveys of presupernova evolution with some important corrections to code physics and four to 10 times better mass resolution in each star. The number of presupernova masses considered is also much larger. Over 4000 models are calculated in the range from 12 to 60 M ⊙ with varying mass loss rates. The core structure is not greatly affected by the increased spatial resolution. The qualitative patterns of compactness measures and their extrema are the same, but with the increased number of models, the scatter seen in previous studies is replaced by several localized branches. More physics-based analyses by Ertl et al. and Müller et al. show these branches with less scatter than the single-parameter characterization of O’Connor & Ott. These branches are particularly apparent for stars in the mass ranges 14–19 and 22–24 M ⊙. The multivalued solutions are a consequence of interference between several carbon- and oxygen-burning shells during the late stages of evolution. For a relevant range of masses, whether a star explodes or not may reflect the small, almost random differences in its late evolution more than its initial mass. The large number of models allows statistically meaningful statements about the radius, luminosity, and effective temperatures of presupernova stars, their core structures, and their remnant mass distributions.

Spontaneous collective synchronization in the Kuramoto model with additional non-local interactions

NASA Astrophysics Data System (ADS)

Gupta, Shamik

2017-10-01

In the context of the celebrated Kuramoto model of globally-coupled phase oscillators of distributed natural frequencies, which serves as a paradigm to investigate spontaneous collective synchronization in many-body interacting systems, we report on a very rich phase diagram in presence of thermal noise and an additional non-local interaction on a one-dimensional periodic lattice. Remarkably, the phase diagram involves both equilibrium and non-equilibrium phase transitions. In two contrasting limits of the dynamics, we obtain exact analytical results for the phase transitions. These two limits correspond to (i) the absence of thermal noise, when the dynamics reduces to that of a non-linear dynamical system, and (ii) the oscillators having the same natural frequency, when the dynamics becomes that of a statistical system in contact with a heat bath and relaxing to a statistical equilibrium state. In the former case, our exact analysis is based on the use of the so-called Ott-Antonsen ansatz to derive a reduced set of nonlinear partial differential equations for the macroscopic evolution of the system. Our results for the case of statistical equilibrium are on the other hand obtained by extending the well-known transfer matrix approach for nearest-neighbor Ising model to consider non-local interactions. The work offers a case study of exact analysis in many-body interacting systems. The results obtained underline the crucial role of additional non-local interactions in either destroying or enhancing the possibility of observing synchrony in mean-field systems exhibiting spontaneous synchronization.

Thin Shell evolution of NIF capsule with asymmetric drive and the resulting neutron diagnostics

NASA Astrophysics Data System (ADS)

Buchoff, Michael; Hammer, Jim

2015-11-01

One of the major impediments to achieving ignition via ICF is the non-spherical implosion arising from small asymmetries in the drive forcing the collapse of the capsule. Likewise, an experimental diagnostic for quantifying the characteristics of the implosion asymmetry is the final state neutrons, whose number and velocity distributions are not experimentally consistent with the expectation of a spherical implosion. In principle, connecting these initial and final state asymmetries could be solved via hydrodynamic simulations, but due to the multiple scales traversed throughout this process, these calculations are difficult and expensive, leaving much of the potential drive asymmetry profiles unexplored. In this work, we solve the resulting analytic equations from the thin-shell model proposed by Ott et. al. to evolve the capsule over a range of different drive asymmetries from its initial state (when the shell aspect ratio is much greater than 1) to a radius of roughly 250 microns, consisting of a layer of dense CH, a cold layer of dense DT, and a warm core of sparsely distributed DT. At this stage, more tractable hydrodynamical simulations are performed in the ARES code suite, determining the distribution of neutron from thermonuclear yield. These and future results allow for a multitude of tests of asymmetric sources to compare with and potentially guide experiment. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

Measurement accuracy of weighing and tipping-bucket rainfall intensity gauges under dynamic laboratory testing

NASA Astrophysics Data System (ADS)

Colli, M.; Lanza, L. G.; La Barbera, P.; Chan, P. W.

2014-07-01

The contribution of any single uncertainty factor in the resulting performance of infield rain gauge measurements still has to be comprehensively assessed due to the high number of real world error sources involved, such as the intrinsic variability of rainfall intensity (RI), wind effects, wetting losses, the ambient temperature, etc. In recent years the World Meteorological Organization (WMO) addressed these issues by fostering dedicated investigations, which revealed further difficulties in assessing the actual reference rainfall intensity in the field. This work reports on an extensive assessment of the OTT Pluvio2 weighing gauge accuracy when measuring rainfall intensity under laboratory dynamic conditions (time varying reference flow rates). The results obtained from the weighing rain gauge (WG) were also compared with a MTX tipping-bucket rain gauge (TBR) under the same test conditions. Tests were carried out by simulating various artificial precipitation events, with unsteady rainfall intensity, using a suitable dynamic rainfall generator. Real world rainfall data measured by an Ogawa catching-type drop counter at a field test site located within the Hong Kong International Airport (HKIA) were used as a reference for the artificial rain generation system. Results demonstrate that the differences observed between the laboratory and field performance of catching-type gauges are only partially attributable to the weather and operational conditions in the field. The dynamics of real world precipitation events is responsible for a large part of the measurement errors, which can be accurately assessed in the laboratory under controlled environmental conditions. This allows for new testing methodologies and the development of instruments with enhanced performance in the field.

Identification of Computational and Experimental Reduced-Order Models

NASA Technical Reports Server (NTRS)

Silva, Walter A.; Hong, Moeljo S.; Bartels, Robert E.; Piatak, David J.; Scott, Robert C.

2003-01-01

The identification of computational and experimental reduced-order models (ROMs) for the analysis of unsteady aerodynamic responses and for efficient aeroelastic analyses is presented. For the identification of a computational aeroelastic ROM, the CFL3Dv6.0 computational fluid dynamics (CFD) code is used. Flutter results for the AGARD 445.6 Wing and for a Rigid Semispan Model (RSM) computed using CFL3Dv6.0 are presented, including discussion of associated computational costs. Modal impulse responses of the unsteady aerodynamic system are computed using the CFL3Dv6.0 code and transformed into state-space form. The unsteady aerodynamic state-space ROM is then combined with a state-space model of the structure to create an aeroelastic simulation using the MATLAB/SIMULINK environment. The MATLAB/SIMULINK ROM is then used to rapidly compute aeroelastic transients, including flutter. The ROM shows excellent agreement with the aeroelastic analyses computed using the CFL3Dv6.0 code directly. For the identification of experimental unsteady pressure ROMs, results are presented for two configurations: the RSM and a Benchmark Supercritical Wing (BSCW). Both models were used to acquire unsteady pressure data due to pitching oscillations on the Oscillating Turntable (OTT) system at the Transonic Dynamics Tunnel (TDT). A deconvolution scheme involving a step input in pitch and the resultant step response in pressure, for several pressure transducers, is used to identify the unsteady pressure impulse responses. The identified impulse responses are then used to predict the pressure responses due to pitching oscillations at several frequencies. Comparisons with the experimental data are then presented.

Towards a better understanding on how large wood is controlling longitudinal sediment (dis)connectivity in mountain streams - concepts and first results

NASA Astrophysics Data System (ADS)

Schuchardt, Anne; Pöppl, Ronald; Morche, David

2016-04-01

Large wood (LW) provides various ecological and morphological functions. Recent research has focused on habitat diversity and abundance, effects on channel planforms, pool formation, flow regimes and increased storage of organic matter as well as storage of fine sediment. While LW studies and sediment transport rates are the focus of numerous research questions, the influence of large channel blocking barriers (e.g. LW) and their impact on sediment trapping and decoupling transportation pathways is less studied. This project tries to diminish the obvious gap and deals with the modifications of the sediment connectivity by LW. To investigate the influence of large wood on sediment transporting processes and sediment connectivity, the spatial distribution and characterization of LW (>1 m in length and >10 cm in diameter) in channels is examined by field mapping and dGPS measurements. Channel hydraulic parameters are determined by field measurements of channel long profiles and cross sections. To quantify the direct effects of LW on discharge and bed load transport the flow velocity and bed load up- and downstream of LW is measured using an Ott-Nautilus and a portable Helley-Smith bed load sampler during different water stages. Sediment storages behind LWD accumulations will be monitored with dGPS. While accumulation of sediment indicates in-channel sediment storage and thus disconnection from downstream bed load transport, erosion of sediment evidences downstream sediment connectivity. First results will be presented from two study areas in mountain ranges in Germany (Wetterstein Mountain Range) and Austria (Bohemian Massif).

Comparison of Ground- and Space-based Radar Observations with Disdrometer Measurements During the PECAN Field Campaign

NASA Astrophysics Data System (ADS)

Torres, A. D.; Rasmussen, K. L.; Bodine, D. J.; Dougherty, E.

2015-12-01

Plains Elevated Convection At Night (PECAN) was a large field campaign that studied nocturnal mesoscale convective systems (MCSs), convective initiation, bores, and low-level jets across the central plains in the United States. MCSs are responsible for over half of the warm-season precipitation across the central U.S. plains. The rainfall from deep convection of these systems over land have been observed to be underestimated by satellite radar rainfall-retrieval algorithms by as much as 40 percent. These algorithms have a strong dependence on the generally unmeasured rain drop-size distribution (DSD). During the campaign, our group measured rainfall DSDs, precipitation fall velocities, and total precipitation in the convective and stratiform regions of MCSs using Ott Parsivel optical laser disdrometers. The disdrometers were co-located with mobile pod units that measured temperature, wind, and relative humidity for quality control purposes. Data from the operational NEXRAD radar in LaCrosse, Wisconsin and space-based radar measurements from a Global Precipitation Measurement satellite overpass on July 13, 2015 were used for the analysis. The focus of this study is to compare DSD measurements from the disdrometers to radars in an effort to reduce errors in existing rainfall-retrieval algorithms. The error analysis consists of substituting measured DSDs into existing quantitative precipitation estimation techniques (e.g. Z-R relationships and dual-polarization rain estimates) and comparing these estimates to ground measurements of total precipitation. The results from this study will improve climatological estimates of total precipitation in continental convection that are used in hydrological studies, climate models, and other applications.

Results from Core-collapse Simulations with Multi-dimensional, Multi-angle Neutrino Transport

NASA Astrophysics Data System (ADS)

Brandt, Timothy D.; Burrows, Adam; Ott, Christian D.; Livne, Eli

2011-02-01

We present new results from the only two-dimensional multi-group, multi-angle calculations of core-collapse supernova evolution. The first set of results from these calculations was published in 2008 by Ott et al. We have followed a nonrotating and a rapidly rotating 20 M sun model for ~400 ms after bounce. We show that the radiation fields vary much less with angle than the matter quantities in the region of net neutrino heating. This happens because most neutrinos are emitted from inner radiative regions and because the specific intensity is an integral over sources from many angles at depth. The latter effect can only be captured by multi-angle transport. We then compute the phase relationship between dipolar oscillations in the shock radius and in matter and radiation quantities throughout the post-shock region. We demonstrate a connection between variations in neutrino flux and the hydrodynamical shock oscillations, and use a variant of the Rayleigh test to estimate the detectability of these neutrino fluctuations in IceCube and Super-Kamiokande. Neglecting flavor oscillations, fluctuations in our nonrotating model would be detectable to ~10 kpc in IceCube, and a detailed power spectrum could be measured out to ~5 kpc. These distances are considerably lower in our rapidly rotating model or with significant flavor oscillations. Finally, we measure the impact of rapid rotation on detectable neutrino signals. Our rapidly rotating model has strong, species-dependent asymmetries in both its peak neutrino flux and its light curves. The peak flux and decline rate show pole-equator ratios of up to ~3 and ~2, respectively.

Comparison of Raindrop Size Distribution Measurements by Collocated Disdrometers

NASA Technical Reports Server (NTRS)

Tokay, Ali; Petersen, Walter A.; Gatlin, Patrick; Wingo, Matthew

2013-01-01

An impact-type Joss-Waldvogel disdrometer (JWD), a two-dimensional video disdrometer (2DVD), and a laser optical OTT Particle Size and Velocity (PARSIVEL) disdrometer (PD) were used to measure the raindrop size distribution (DSD) over a 6-month period in Huntsville, Alabama. Comparisons indicate event rain totals for all three disdrometers that were in reasonable agreement with a reference rain gauge. In a relative sense, hourly composite DSDs revealed that the JWD was more sensitive to small drops (,1 mm), while the PD appeared to severely underestimate small drops less than 0.76mm in diameter. The JWD and 2DVD measured comparable number concentrations of midsize drops (1-3mm) and large drops (3-5 mm), while the PD tended to measure relatively higher drop concentrations at sizes larger than 2.44mm in diameter. This concentration disparity tended to occur when hourly rain rates and drop counts exceeded 2.5mm/h and 400/min, respectively. Based on interactions with the PD manufacturer, the partially inhomogeneous laser beam is considered the cause of the PD drop count overestimation. PD drop fall speeds followed the expected terminal fall speed relationship quite well, while the 2DVD occasionally measured slower drops for diameters larger than 2.4mm, coinciding with events where wind speeds were greater than 4m/s. The underestimation of small drops by the PD had a pronounced effect on the intercept and shape of parameters of gamma-fitted DSDs, while the overestimation of midsize and larger drops resulted in higher mean values for PD integral rain parameters

Linear analysis on the growth of non-spherical perturbations in supersonic accretion flows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Takahashi, Kazuya; Yamada, Shoichi, E-mail: ktakahashi@heap.phys.waseda.ac.jp

We analyzed the growth of non-spherical perturbations in supersonic accretion flows. We have in mind an application to the post-bounce phase of core-collapse supernovae (CCSNe). Such non-spherical perturbations have been suggested by a series of papers by Arnett, who has numerically investigated violent convections in the outer layers of pre-collapse stars. Moreover, Couch and Ott demonstrated in their numerical simulations that such perturbations may lead to a successful supernova even for a progenitor that fails to explode without fluctuations. This study investigated the linear growth of perturbations during the infall onto a stalled shock wave. The linearized equations are solvedmore » as an initial and boundary value problem with the use of a Laplace transform. The background is a Bondi accretion flow whose parameters are chosen to mimic the 15 M {sub ☉} progenitor model by Woosley and Heger, which is supposed to be a typical progenitor of CCSNe. We found that the perturbations that are given at a large radius grow as they flow down to the shock radius; the density perturbations can be amplified by a factor of 30, for example. We analytically show that the growth rate is proportional to l, the index of the spherical harmonics. We also found that the perturbations oscillate in time with frequencies that are similar to those of the standing accretion shock instability. This may have an implication for shock revival in CCSNe, which will be investigated in our forthcoming paper in more detail.« less

Improvement of Olfactory Function With High Frequency Non-invasive Auricular Electrostimulation in Healthy Humans

PubMed Central

Maharjan, Ashim; Wang, Eunice; Peng, Mei; Cakmak, Yusuf O.

2018-01-01

In past literature on animal models, invasive vagal nerve stimulation using high frequencies has shown to be effective at modulating the activity of the olfactory bulb (OB). Recent advances in invasive vagal nerve stimulation in humans, despite previous findings in animal models, used low frequency stimulation and found no effect on the olfactory functioning. The present article aimed to test potential effects of non-invasive, high and low frequency vagal nerve stimulation in humans, with supplementary exploration of the orbitofrontal cortex using near-infrared spectroscopy (NIRS). Healthy, male adult participants (n = 18) performed two olfactory tests [odor threshold test (OTT) and supra-threshold test (STT)] before and after receiving high-, low frequency vagal nerve stimulation and placebo (no stimulation). Participant's olfactory functioning was monitored using NIRS, and assessed with two behavioral olfactory tests. NIRS data of separate stimulation parameters were statistically analyzed using repeated-measures ANOVA across different stages. Data from olfactory tests were analyzed using paired parametric and non-parametric statistical tests. Only high frequency, non-invasive vagal nerve stimulation was able to positively modulate the performance of the healthy participants in the STT (p = 0.021, Wilcoxon sign-ranked test), with significant differences in NIRS (p = 0.014, post-hoc with Bonferroni correction) recordings of the right hemispheric, orbitofrontal cortex. The results from the current article implore further exploration of the neurocircuitry involved under vagal nerve stimulation and the effects of non-invasive, high frequency, vagal nerve stimulation toward olfactory dysfunction which showcase in Parkinson's and Alzheimer's Diseases. Despite the sufficient effect size (moderate effect, correlation coefficient (r): 0.39 for the STT) of the current study, future research should replicate the current findings with a larger cohort. PMID:29740266

Factors associated with pharmacists' perceptions of their working conditions and safety and effectiveness of patient care.

PubMed

Tsao, Nicole W; Lynd, Larry D; Gastonguay, Louise; Li, Kathy; Nakagawa, Bob; Marra, Carlo A

2016-01-01

In recent years, the role of pharmacists has changed, as have various provincial legislations, which now allow pharmacists to provide additional health services to patients. With these changes comes growing concern about how well the current pharmacy working environment is adapting and whether it may also be creating work-related stress that may contribute to potentially unsafe practices of patient care. To characterize the current working conditions of pharmacists in British Columbia, an online survey was developed and distributed to all College of Pharmacists of BC (CPBC) registrants by email. The survey consisted of questions on pharmacists' demographics, practice setting and perceptions of workplace conditions. Responses were collected from October 1 to November 10, 2013. All data were summarized using descriptive statistics, and regression models were constructed to assess the association between various factors and pharmacists' self-reported working conditions. Twenty-three percent (1241/5300) of pharmacists registered with the CPBC responded, with 78% working in the community pharmacy setting (58% chain, 19% independent). Pharmacists mostly disagreed with the statements that they had enough time for breaks or lunches or to do their jobs, as well as enough staffing support. Pharmacists' perceptions of their workplace environment were negatively associated with workplace-imposed advanced service quotas (for medication reviews, immunizations and prescription adaptations); being employed at chain store pharmacies, compared to independent pharmacies or hospitals/long-term care settings; and higher prescription volume. Pharmacists working in chain community pharmacies who are required to meet monthly quotas for expanded services reported a substantial negative impact on their working conditions and perceived safety of patient care. Can Pharm J (Ott) 2016;149:xx-xx.

Depression Prevalence and Exposure to Organophosphate Esters in Aircraft Maintenance Workers.

PubMed

Hardos, Jennifer E; Whitehead, Lawrence W; Han, Inkyu; Ott, Darrin K; Waller, D Kim

2016-08-01

Previous studies found that aircraft maintenance workers may be exposed to organophosphates in hydraulic fluid and engine oil. Studies have also illustrated a link between long-term low-level organophosphate pesticide exposure and depression. A questionnaire containing the Patient Health Questionnaire 8 depression screener was e-mailed to 52,080 aircraft maintenance workers (with N = 4801 complete responses) in a cross-sectional study to determine prevalence and severity of depression and descriptions of their occupational exposures. There was no significant difference between reported depression prevalence and severity in similar exposure groups in which aircraft maintenance workers were exposed or may have been exposed to organophosphate esters compared to similar exposure groups in which they were not exposed. However, a dichotomous measure of the prevalence of depression was significantly associated with self-reported exposure levels from low (OR: 1.21) to moderate (OR: 1.68) to high exposure (OR: 2.70) and with each exposure route including contact (OR: 1.68), inhalation (OR: 2.52), and ingestion (OR: 2.55). A self-reported four-level measure of depression severity was also associated with a self-reported four-level measure of exposure. Based on self-reported exposures and outcomes, an association is observed between organophosphate exposure and depression; however, we cannot assume that the associations we observed are causal because some workers may have been more likely to report exposure to organophosphate esters and also more likely to report depression. Future studies should consider using a larger sample size, better methods for characterizing crew chief exposures, and bioassays to measure dose rather than exposure. Hardos JE, Whitehead LW, Han I, Ott DK, Waller DK. Depression prevalence and exposure to organophosphate esters in aircraft maintenance workers. Aerosp Med Hum Perform. 2016; 87(8):712-717.

Improvement of Olfactory Function With High Frequency Non-invasive Auricular Electrostimulation in Healthy Humans.

PubMed

Maharjan, Ashim; Wang, Eunice; Peng, Mei; Cakmak, Yusuf O

2018-01-01

In past literature on animal models, invasive vagal nerve stimulation using high frequencies has shown to be effective at modulating the activity of the olfactory bulb (OB). Recent advances in invasive vagal nerve stimulation in humans, despite previous findings in animal models, used low frequency stimulation and found no effect on the olfactory functioning. The present article aimed to test potential effects of non-invasive, high and low frequency vagal nerve stimulation in humans, with supplementary exploration of the orbitofrontal cortex using near-infrared spectroscopy (NIRS). Healthy, male adult participants ( n = 18) performed two olfactory tests [odor threshold test (OTT) and supra-threshold test (STT)] before and after receiving high-, low frequency vagal nerve stimulation and placebo (no stimulation). Participant's olfactory functioning was monitored using NIRS, and assessed with two behavioral olfactory tests. NIRS data of separate stimulation parameters were statistically analyzed using repeated-measures ANOVA across different stages. Data from olfactory tests were analyzed using paired parametric and non-parametric statistical tests. Only high frequency, non-invasive vagal nerve stimulation was able to positively modulate the performance of the healthy participants in the STT ( p = 0.021, Wilcoxon sign-ranked test), with significant differences in NIRS ( p = 0.014, post-hoc with Bonferroni correction ) recordings of the right hemispheric, orbitofrontal cortex. The results from the current article implore further exploration of the neurocircuitry involved under vagal nerve stimulation and the effects of non-invasive, high frequency, vagal nerve stimulation toward olfactory dysfunction which showcase in Parkinson's and Alzheimer's Diseases. Despite the sufficient effect size (moderate effect, correlation coefficient (r): 0.39 for the STT) of the current study, future research should replicate the current findings with a larger cohort.

How do community pharmacists make decisions? Results of an exploratory qualitative study in Ontario.

PubMed

Gregory, Paul A M; Whyte, Brenna; Austin, Zubin

2016-03-01

As the complexity of pharmacy practice increases, pharmacists are required to make more decisions under ambiguous or information-deficient conditions. There is scant literature examining how pharmacists make decisions and what factors or values influence their choices. The objective of this exploratory research was to characterize decision-making patterns in the clinical setting of community pharmacists in Ontario. The think-aloud decision-making method was used for this study. Community pharmacists with 3 or more years' experience were presented with 2 clinical case studies dealing with challenging situations and were asked to verbally reason through their decision-making process while being probed by an interviewer for clarification, justification and further explication. Verbatim transcripts were analyzed using a protocol analysis method. A total of 12 pharmacists participated in this study. Participants experienced cognitive dissonance in attempting to reconcile their desire for a clear and confrontation-free conclusion to the case discussion and the reality of the challenge presented within each case. Strategies for resolving this cognitive dissonance included strong emphasis on the educational (rather than decision-making) role of the pharmacist, the value of strong interpersonal relationships as a way to avoid conflict and achieve desired outcomes, the desire to seek external advice or defer to others' authority to avoid making a decision and the use of strict interpretations of rules to avoid ambiguity and contextual interpretation. This research was neither representative nor generalizable but was indicative of patterns of decisional avoidance and fear of assuming responsibility for outcomes that warrant further investigation. The think-aloud method functioned effectively in this context and provided insights into pharmacists' decision-making patterns in the clinical setting. Can Pharm J (Ott) 2016;149:90-98.

Checkerboard seed-blanket thorium fuel core concepts for heavy water moderated reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bromley, B.P.; Hyland, B.

2013-07-01

New reactor concepts to implement thorium-based fuel cycles have been explored to achieve maximum resource utilization. Pressure tube heavy water reactors (PT-HWR) are highly advantageous for implementing the use of thorium-based fuels because of their high neutron economy and on-line re-fuelling capability. The use of heterogeneous seed-blanket core concepts in a PT-HWR where higher-fissile-content seed fuel bundles are physically separate from lower-fissile-content blanket bundles allows more flexibility and control in fuel management to maximize the fissile utilization and conversion of fertile fuel. The lattice concept chosen was a 35-element bundle made with a homogeneous mixture of reactor grade Pu (aboutmore » 67 wt% fissile) and Th, and with a central zirconia rod to help reduce coolant void reactivity. Several checkerboard heterogeneous seed-blanket core concepts with plutonium-thorium-based fuels in a 700-MWe-class PT-HWR were analyzed, using a once-through thorium (OTT) cycle. Different combinations of seed and blanket fuel were tested to determine the impact on core-average burnup, fissile utilization, power distributions, and other performance parameters. It was found that various checkerboard core concepts can achieve a fissile utilization that is up to 26% higher than that achieved in a PT-HWR using more conventional natural uranium fuel bundles. Up to 60% of the Pu is consumed; up to 43% of the energy is produced from thorium, and up to 303 kg/year of Pa-233/U-233/U-235 are produced. Checkerboard cores with about 50% of low-power blanket bundles may require power de-rating (65% to 74%) to avoid exceeding maximum limits for channel and bundle powers and linear element ratings. (authors)« less

Annular seed-blanket thorium fuel core concepts for heavy water moderated reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bromley, B.P.; Hyland, B.

2013-07-01

New reactor concepts to implement thorium-based fuel cycles have been explored to achieve maximum resource utilization. Pressure tube heavy water reactors (PT-HWR) are highly advantageous for implementing the use of thorium-based fuels because of their high neutron economy and on-line re-fuelling capability. The use of heterogeneous seed-blanket core concepts in a PT-HWR where higher-fissile-content seed fuel bundles are physically separate from lower-fissile-content blanket bundles allows more flexibility and control in fuel management to maximize the fissile utilization and conversion of fertile fuel. The lattice concept chosen is a 35-element bundle made with a homogeneous mixture of reactor grade Pu andmore » Th, and with a central zirconia rod to help reduce coolant void reactivity. Several annular heterogeneous seed-blanket core concepts with plutonium-thorium-based fuels in a 700-MWe-class PT-HWR were analyzed, using a once-through thorium (OTT) cycle. Different combinations of seed and blanket fuel were tested to determine the impact on core-average burnup, fissile utilization, power distributions, and other performance parameters. It was found that the various core concepts can achieve a fissile utilization that is up to 30% higher than is currently achieved in a PT-HWR using conventional natural uranium fuel bundles. Up to 67% of the Pu is consumed; up to 43% of the energy is produced from thorium, and up to 363 kg/year of U-233 is produced. Seed-blanket cores with ∼50% content of low-power blanket bundles may require power de-rating (∼58% to 65%) to avoid exceeding maximum limits for peak channel power, bundle power and linear element ratings. (authors)« less

Evaluation of the Hydrolab HL4 water-quality sonde and sensors

USGS Publications Warehouse

Snazelle, Teri T.

2017-12-18

The U.S. Geological Survey (USGS) Hydrologic Instrumentation Facility evaluated three Hydrolab HL4 multiparameter water-quality sondes by OTT Hydromet. The sondes were equipped with temperature, conductivity, pH, dissolved oxygen (DO), and turbidity sensors. The sensors were evaluated for compliance with the USGS National Field Manual for the Collection of Water-Quality Data (NFM) criteria for continuous water-quality monitors and to verify the validity of the manufacturer’s technical specifications. The conductivity sensors were evaluated for the accuracy of the specific conductance (SC) values (conductance at 25 degrees Celsius [oC]), that were calculated by using the vendor default method, Hydrolab Fresh. The HL4’s communication protocols and operating temperature range along with accuracy of the water-quality sensors were tested in a controlled laboratory setting May 1–19, 2016. To evaluate the sonde’s performance in a surface-water field application, an HL4 equipped with temperature, conductivity, pH, DO, and turbidity sensors was deployed June 20–July 22, 2016, at USGS water-monitoring site 02492620, Pearl River at National Space Technology Laboratories (NSTL) Station, Mississippi, located near Bay Saint Louis, Mississippi, and compared to the adjacent well-maintained EXO2 site sonde.The three HL4 sondes met the USGS temperature testing criteria and the manufacturer’s technical specifications for temperature based upon the median room temperature difference between the measured and standard temperatures, but two of the three sondes exceeded the allowable difference criteria at the temperature extremes of approximately 5 and 40 ºC. Two sondes met the USGS criteria for SC. One of the sondes failed the criteria for SC when evaluated in a 100,000-microsiemens-per-centimeter (μS/cm) standard at room temperature, and also failed in a 10,000-μS/cm standard at 5, 15, and 40 ºC. All three sondes met the USGS criteria for pH and DO at room temperature, but one sonde exceeded the allowable difference criteria when tested in pH 5.00 buffer and at 40 ºC. The USGS criteria and the technical specifications for turbidity were met by one sonde in standards ranging from 10 to 3,000 nephelometric turbidity units (NTU). A second sonde met the USGS criteria and the technical specifications except in the 3,000-NTU standard, and the third sonde exceeded the USGS calibration criteria in the 10- and 20-NTU standards and the technical specifications in the 20-NTU standard.Results of the field test showed acceptable performance and revealed that differences in data sample processing between sonde manufacturers may result in variances between the reported measurements when comparing one sonde to another. These variances in data would be more pronounced in dynamic site conditions. The lack of a wiper or other sensor-cleaning device on the DO sensor could prove problematic, and could limit the use of the HL4 to profiling applications or at sites with limited biofouling.

Hydrologic Instrumentation of Field Sites to Understand Short Term Changes in Water Quality

NASA Astrophysics Data System (ADS)

Iqbal, M. Z.; Clayton, M.

2011-12-01

This project is funded by a successful NSF-CCLI grant currently in effect. The objective of this project is to build a real time water quality monitoring facility by the Dry Run Creek on the University of Northern Iowa campus. The long term goal is to turn this site into a model outdoor educational resource for students to study the critical elements of the hydrologic environment. Weekly class sessions otherwise make it difficult for students to deal with the daily changes is water chemistry. Upon completion of the project, students will be able to look at the diurnal variations in the water quality through a website available for public viewing. Besides, they will have the opportunity to participate in a variety of research and learning activities directly at the site. Four (4) pieces of instruments are in the process of being installed at the experimental site. The instruments are 1) YSI 6600 V2 extended deployment probe to measure water quality parameters in the Dry Run Creek (i.e., pH, Total Dissolved Solids, conductivity, Dissolved Oxygen, temperature, turbidity, chlorophyll, etc.); 2) OTT RLS Radar to measure water level fluctuations in the creek; 3) Hydrolab MS5 mini-sonde to continuously measure pH, TDS, conductivity, DO, temperature, turbidity, and nitrate in a 70 ft deep ground water well on the site; and 4) DL 3000 data logger to receive all data from the above 3 pieces of equipment and automatically upload them to a website. Site preparation, including digging trenches for data cable and electric wires has been completed. Instrumental calibration is in progress and the site is expected to be up and running soon. We expect that this well site expansion plan will considerably strengthen our hydrology curriculum and facilitate more effective dissemination of the project outcome.

Chimera states in two-dimensional networks of locally coupled oscillators

NASA Astrophysics Data System (ADS)

Kundu, Srilena; Majhi, Soumen; Bera, Bidesh K.; Ghosh, Dibakar; Lakshmanan, M.

2018-02-01

Chimera state is defined as a mixed type of collective state in which synchronized and desynchronized subpopulations of a network of coupled oscillators coexist and the appearance of such anomalous behavior has strong connection to diverse neuronal developments. Most of the previous studies on chimera states are not extensively done in two-dimensional ensembles of coupled oscillators by taking neuronal systems with nonlinear coupling function into account while such ensembles of oscillators are more realistic from a neurobiological point of view. In this paper, we report the emergence and existence of chimera states by considering locally coupled two-dimensional networks of identical oscillators where each node is interacting through nonlinear coupling function. This is in contrast with the existence of chimera states in two-dimensional nonlocally coupled oscillators with rectangular kernel in the coupling function. We find that the presence of nonlinearity in the coupling function plays a key role to produce chimera states in two-dimensional locally coupled oscillators. We analytically verify explicitly in the case of a network of coupled Stuart-Landau oscillators in two dimensions that the obtained results using Ott-Antonsen approach and our analytical finding very well matches with the numerical results. Next, we consider another type of important nonlinear coupling function which exists in neuronal systems, namely chemical synaptic function, through which the nearest-neighbor (locally coupled) neurons interact with each other. It is shown that such synaptic interacting function promotes the emergence of chimera states in two-dimensional lattices of locally coupled neuronal oscillators. In numerical simulations, we consider two paradigmatic neuronal oscillators, namely Hindmarsh-Rose neuron model and Rulkov map for each node which exhibit bursting dynamics. By associating various spatiotemporal behaviors and snapshots at particular times, we study the chimera states in detail over a large range of coupling parameter. The existence of chimera states is confirmed by instantaneous angular frequency, order parameter and strength of incoherence.

Characterisation of Growth and Ultrastructural Effects of the Xanthoria elegans Photobiont After 1.5 Years of Space Exposure on the International Space Station

NASA Astrophysics Data System (ADS)

Brandt, Annette; Posthoff, Eva; de Vera, Jean-Pierre; Onofri, Silvano; Ott, Sieglinde

2016-06-01

The lichen Xanthoria elegans has been exposed to space and simulated Mars-analogue environment in the Lichen and Fungi Experiment (LIFE) on the EXPOSE-E facility at the International Space Station (ISS). This long-term exposure of 559 days tested the ability of various organisms to cope with either low earth orbit (LEO) or Mars-analogue conditions, such as vacuum, Mars-analogue atmosphere, rapid temperature cycling, cosmic radiation of up to 215 ± 16 mGy, and insolation of accumulated doses up to 4.87 GJm-2, including up to 0.314 GJm-2 of UV irradiation. In a previous study, X. elegans demonstrated considerable resistance towards these conditions by means of photosynthetic activity as well as by post-exposure metabolic activity of 50-80 % in the algal and 60-90 % in the fungal symbiont (Brandt et al. Int J Astrobiol 14(3):411-425, 2015). The two objectives of the present study were complementary: First, to verify the high post-exposure viability by using a qualitative cultivation assay. Second, to characterise the cellular damages by transmission electron microscopy (TEM) which were caused by the space and Mars-analogue exposure conditions of LIFE. Since the algal symbiont of lichens is considered as the more susceptible partner (de Vera and Ott 2010), the analyses focused on the photobiont. The study demonstrated growth and proliferation of the isolated photobiont after all exposure conditions of LIFE. The ultrastructural analysis of the algal cells provided an insight to cellular damages caused by long-term exposure and highlighted that desiccation-induced breakdown of cellular integrity is more pronounced under the more severe space vacuum than under Mars-analogue atmospheric conditions. In conclusion, desiccation-induced damages were identified as a major threat to the photobiont of X. elegans. Nonetheless, a fraction of the photobiont cells remained cultivable after all exposure conditions tested in LIFE.

Block ground interaction of rockfalls

NASA Astrophysics Data System (ADS)

Volkwein, Axel; Gerber, Werner; Kummer, Peter

2016-04-01

During a rockfall the interaction of the falling block with the ground is one of the most important factors that define the evolution of a rockfall trajectory. It steers the rebound, the rotational movement, possibly brake effects, friction losses and damping effects. Therefore, if most reliable rockfall /trajectory simulation software is sought a good understanding of the block ground interaction is necessary. Today's rockfall codes enable the simulation of a fully 3D modelled block within a full 3D surface . However, the details during the contact, i.e. the contact duration, the penetration depth or the dimension of the marks in the ground are usually not part of the simulation. Recent field tests with rocks between 20 and 80 kg have been conducted on a grassy slope in 2014 [1]. A special rockfall sensor [2] within the blocks measured the rotational velocity and the acting accelerations during the tests. External video records and a so-called LocalPositioningSystem deliver information on the travel velocity. With these data not only the flight phases of the trajectories but also the contacts with the ground can be analysed. During the single jumps of a block the flight time, jump length, the velocity, and the rotation are known. During the single impacts their duration and the acting accelerations are visible. Further, the changes of rotational and translational velocity influence the next jump of the block. The change of the rotational velocity over the whole trajectory nicely visualizes the different phases of a rockfall regarding general acceleration and deceleration in respect to the inclination and the topography of the field. References: [1] Volkwein A, Krummenacher B, Gerber W, Lardon J, Gees F, Brügger L, Ott T (2015) Repeated controlled rockfall trajectory testing. [Abstract] Geophys. Res. Abstr. 17: EGU2015-9779. [2] Volkwein A, Klette J (2014) Semi-Automatic Determination of Rockfall Trajectories. Sensors 14: 18187-18210.

Nonlinear Dynamics, Chaotic and Complex Systems

NASA Astrophysics Data System (ADS)

Infeld, E.; Zelazny, R.; Galkowski, A.

2011-04-01

Part I. Dynamic Systems Bifurcation Theory and Chaos: 1. Chaos in random dynamical systems V. M. Gunldach; 2. Controlling chaos using embedded unstable periodic orbits: the problem of optimal periodic orbits B. R. Hunt and E. Ott; 3. Chaotic tracer dynamics in open hydrodynamical flows G. Karolyi, A. Pentek, T. Tel and Z. Toroczkai; 4. Homoclinic chaos L. P. Shilnikov; Part II. Spatially Extended Systems: 5. Hydrodynamics of relativistic probability flows I. Bialynicki-Birula; 6. Waves in ionic reaction-diffusion-migration systems P. Hasal, V. Nevoral, I. Schreiber, H. Sevcikova, D. Snita, and M. Marek; 7. Anomalous scaling in turbulence: a field theoretical approach V. Lvov and I. Procaccia; 8. Abelian sandpile cellular automata M. Markosova; 9. Transport in an incompletely chaotic magnetic field F. Spineanu; Part III. Dynamical Chaos Quantum Physics and Foundations Of Statistical Mechanics: 10. Non-equilibrium statistical mechanics and ergodic theory L. A. Bunimovich; 11. Pseudochaos in statistical physics B. Chirikov; 12. Foundations of non-equilibrium statistical mechanics J. P. Dougherty; 13. Thermomechanical particle simulations W. G. Hoover, H. A. Posch, C. H. Dellago, O. Kum, C. G. Hoover, A. J. De Groot and B. L. Holian; 14. Quantum dynamics on a Markov background and irreversibility B. Pavlov; 15. Time chaos and the laws of nature I. Prigogine and D. J. Driebe; 16. Evolutionary Q and cognitive systems: dynamic entropies and predictability of evolutionary processes W. Ebeling; 17. Spatiotemporal chaos information processing in neural networks H. Szu; 18. Phase transitions and learning in neural networks C. Van den Broeck; 19. Synthesis of chaos A. Vanecek and S. Celikovsky; 20. Computational complexity of continuous problems H. Wozniakowski; Part IV. Complex Systems As An Interface Between Natural Sciences and Environmental Social and Economic Sciences: 21. Stochastic differential geometry in finance studies V. G. Makhankov; Part V. Conference Banquet Speech: Where will the future go? M. J. Feigenbaum.

Characterisation and quantification of groundwater-surface water interactions along an alluvial stream using geophysical, hydraulic and tracer methods

NASA Astrophysics Data System (ADS)

Rumph Frederiksen, R.; Rasmussen, K. R.; Christensen, S.

2015-12-01

Qualifying and quantifying water, nutrient and contaminant exchange at the groundwater-surface water interface are becoming increasingly important for water resources management. The objectives of this study are to characterise an alluvial stream using geophysics in addition to traditional geological and geomorphological data and quantify the groundwater seepage to the stream on point-to-reach scale using both hydraulic and tracer methods. We mapped the very shallow subsurface along an alluvial stream using a GCM system (DUALEM421S, an electromagnetic system that can be operated behind a boat or towed behind a motorized vehicle) as well as using geological logs from a large number of old wells. Furthermore we made geomorphological observations through digital maps (old topographical maps and aerial photos) and field observations. We measured stream discharge (quasi-) simultaneously at several positions along the stream using both an Ott-C31 propeller instrument and an Acoustic Doppler Current Profiler instrument. The measurements were made during dry summer periods when baseflow is expected to be the dominating contribution to streamflow. Preliminary findings show that the GCM system reveals small-scale structures not seen with other data types. Furthermore, based on the GCM results and stream discharge results we have identified gaining, losing and zero exchange sections of the stream. During late summer 2015 we will collect additional hydrological data in order to support or modify our preliminary findings. To further investigate the spatial and temporal variations of the groundwater-surface water interactions along the stream we will measure groundwater seepage to the stream using: seepage meter (point-scale) DTS (reach-scale) temperature stick measurements (point-in-space-and-time-scale) temperature loggers installed in the streambed (month-scale) The measurement sites are chosen based on our geophysical, geological, and geomorphological mapping as well as our stream discharge measurements.

The impact of a windshield in a tipping bucket rain gauge on the reduction of losses in precipitation measurements during snowfall events

NASA Astrophysics Data System (ADS)

Buisan, Samuel T.; Collado, Jose Luis; Alastrue, Javier

2016-04-01

The amount of snow available controls the ecology and hydrological response of mountainous areas and cold regions and affects economic activities including winter tourism, hydropower generation, floods and water supply. An accurate measurement of snowfall accumulation amount is critical and source of error for a better evaluation and verification of numerical weather forecast, hydrological and climate models. It is well known that the undercatch of solid precipitation resulting from wind-induced updrafts at the gauge orifice is the main factor affecting the quality and accuracy of the amount of snowfall precipitation. This effect can be reduced by the use of different windshields. Overall, Tipping Bucket Rain Gauges (TPBRG) provide a large percentage of the precipitation amount measurements, in all climate regimes, estimated at about 80% of the total of observations by automatic instruments. In the frame of the WMO-SPICE project, we compared at the Formigal-Sarrios station (Spanish Pyrenees, 1800 m a.s.l.) the measured precipitation in two heated TPBRGs, one of them protected with a single alter windshield in order to reduce the wind bias. Results were contrasted with measured precipitation using the SPICE reference gauge (Pluvio2 OTT) in a Double Fence Intercomparison Reference (DFIR). Results reported that shielded reduces undercatch up to 40% when wind speed exceeds 6 m/s. The differences when compared with the reference gauge reached values higher than 70%. The inaccuracy of these measurements showed a significant impact in nowcasting operations and climatology in Spain, especially during some heavy snowfall episodes. Also, hydrological models showed a better agreement with the observed rivers flow when including the precipitation not accounted during these snowfall events. The conclusions of this experiment will be used to take decisions on the suitability of the installation of windshields in stations characterized by a large quantity of snowfalls during the winter season and which are mainly located in Northern Spain

Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international study

PubMed Central

Zhou, Yinmei; Abla, Oussama; Adachi, Souichi; Auvrignon, Anne; Beverloo, H. Berna; de Bont, Eveline; Chang, Tai-Tsung; Creutzig, Ursula; Dworzak, Michael; Elitzur, Sarah; Fynn, Alcira; Forestier, Erik; Hasle, Henrik; Liang, Der-Cherng; Lee, Vincent; Locatelli, Franco; Masetti, Riccardo; De Moerloose, Barbara; Reinhardt, Dirk; Rodriguez, Laura; Van Roy, Nadine; Shen, Shuhong; Taga, Takashi; Tomizawa, Daisuke; Yeoh, Allen E. J.; Zimmermann, Martin; Raimondi, Susana C.

2015-01-01

Comprehensive clinical studies of patients with acute megakaryoblastic leukemia (AMKL) are lacking. We performed an international retrospective study on 490 patients (age ≤18 years) with non–Down syndrome de novo AMKL diagnosed from 1989 to 2009. Patients with AMKL (median age 1.53 years) comprised 7.8% of pediatric AML. Five-year event-free (EFS) and overall survival (OS) were 43.7% ± 2.7% and 49.0% ± 2.7%, respectively. Patients diagnosed in 2000 to 2009 were treated with higher cytarabine doses and had better EFS (P = .037) and OS (P = .003) than those diagnosed in 1989 to 1999. Transplantation in first remission did not improve survival. Cytogenetic data were available for 372 (75.9%) patients: hypodiploid (n = 18, 4.8%), normal karyotype (n = 49, 13.2%), pseudodiploid (n = 119, 32.0%), 47 to 50 chromosomes (n = 142, 38.2%), and >50 chromosomes (n = 44, 11.8%). Chromosome gain occurred in 195 of 372 (52.4%) patients: +21 (n = 106, 28.5%), +19 (n = 93, 25.0%), +8 (n = 77, 20.7%). Losses occurred in 65 patients (17.5%): –7 (n = 13, 3.5%). Common structural chromosomal aberrations were t(1;22)(p13;q13) (n = 51, 13.7%) and 11q23 rearrangements (n = 38, 10.2%); t(9;11)(p22;q23) occurred in 21 patients. On the basis of frequency and prognosis, AMKL can be classified to 3 risk groups: good risk—7p abnormalities; poor risk—normal karyotypes, –7, 9p abnormalities including t(9;11)(p22;q23)/MLL-MLLT3, –13/13q-, and –15; and intermediate risk—others including t(1;22)(p13;q13)/OTT-MAL (RBM15-MKL1) and 11q23/MLL except t(9;11). Risk-based innovative therapy is needed to improve patient outcomes. PMID:26215111

The Laboratory Rotational Spectrum of Iso-Propyl Cyanide and AN Astronomical Search in Sagittarius B2(N)

NASA Astrophysics Data System (ADS)

Müller, Holger S. P.; Coutens, A.; Walters, A.; Grabow, J.-U.; Belloche, A.; Menten, K. M.; Schlemmer, S.

2009-06-01

We have carried out a molecular line survey of Sagittarius B2(N) in the 3 mm region with selected recordings at 2 and 1.3 mm to probe the chemical complexity in massive star-forming regions. Noteworthy results include the detection of aminoacetonitrile, a possible precursor of the aminoacid glycine, the detection of ^{13}C isotopologs of vinyl cyanide, and the detection of ethyl formate as well as normal-propyl cyanide. The heavy atoms in the latter molecule form a chain. An isomer with a branched structure, iso-propyl cyanide, also exists, but its rotational spectrum has only been recorded in few transitions up to 40 GHz. Therefore, laboratory measurements were extended. The molecule is rather asymmetric (κ = -0.5766) with a strong a-dipole moment component of 4.05 (2) D and a still sizable c-component of 1.4 (2) D.^e Measurements in Köln were carried out in selected regions between 40 and 600 GHz. Since the c-type transitions appeared to be weaker than predicted additional Stark (and also zero-field) measurements have been carried out in Hannover between 6 and 20 GHz. We will present results of these laboratory spectroscopic investigations as well as the outcome of a search for the molecule in our Sgr B2(N) line survey. A. Belloche, K. M. Menten, C. Comito, H. S. P. Müller, P. Schilke, J. Ott, S. Thorwirth, C. Hieret, Astron. Astrophys. 482 (2008) 179; Erratum 492 (2008) 796. H. S. P. Müller, A. Belloche, K. M. Menten, C. Comito, P. Schilke, J. Mol. Spectrosc. 251 (2008) 319. A. Belloche, R. T. Garrod, H. S. P. Müller, K. M. Menten, C. Comito, P. Schilke, Astron. Astrophys. (2009), accepted. G. E. Herberich, Z. Naturforsch. 22a (1967) 543. J. R. Durig, Y. S. Li, J. Mol. Struct. 21 (1974) 289.

Chimera states in two-dimensional networks of locally coupled oscillators.

PubMed

Kundu, Srilena; Majhi, Soumen; Bera, Bidesh K; Ghosh, Dibakar; Lakshmanan, M

2018-02-01

Chimera state is defined as a mixed type of collective state in which synchronized and desynchronized subpopulations of a network of coupled oscillators coexist and the appearance of such anomalous behavior has strong connection to diverse neuronal developments. Most of the previous studies on chimera states are not extensively done in two-dimensional ensembles of coupled oscillators by taking neuronal systems with nonlinear coupling function into account while such ensembles of oscillators are more realistic from a neurobiological point of view. In this paper, we report the emergence and existence of chimera states by considering locally coupled two-dimensional networks of identical oscillators where each node is interacting through nonlinear coupling function. This is in contrast with the existence of chimera states in two-dimensional nonlocally coupled oscillators with rectangular kernel in the coupling function. We find that the presence of nonlinearity in the coupling function plays a key role to produce chimera states in two-dimensional locally coupled oscillators. We analytically verify explicitly in the case of a network of coupled Stuart-Landau oscillators in two dimensions that the obtained results using Ott-Antonsen approach and our analytical finding very well matches with the numerical results. Next, we consider another type of important nonlinear coupling function which exists in neuronal systems, namely chemical synaptic function, through which the nearest-neighbor (locally coupled) neurons interact with each other. It is shown that such synaptic interacting function promotes the emergence of chimera states in two-dimensional lattices of locally coupled neuronal oscillators. In numerical simulations, we consider two paradigmatic neuronal oscillators, namely Hindmarsh-Rose neuron model and Rulkov map for each node which exhibit bursting dynamics. By associating various spatiotemporal behaviors and snapshots at particular times, we study the chimera states in detail over a large range of coupling parameter. The existence of chimera states is confirmed by instantaneous angular frequency, order parameter and strength of incoherence.

Characterisation of Growth and Ultrastructural Effects of the Xanthoria elegans Photobiont After 1.5 Years of Space Exposure on the International Space Station.

PubMed

Brandt, Annette; Posthoff, Eva; de Vera, Jean-Pierre; Onofri, Silvano; Ott, Sieglinde

2016-06-01

The lichen Xanthoria elegans has been exposed to space and simulated Mars-analogue environment in the Lichen and Fungi Experiment (LIFE) on the EXPOSE-E facility at the International Space Station (ISS). This long-term exposure of 559 days tested the ability of various organisms to cope with either low earth orbit (LEO) or Mars-analogue conditions, such as vacuum, Mars-analogue atmosphere, rapid temperature cycling, cosmic radiation of up to 215 ± 16 mGy, and insolation of accumulated doses up to 4.87 GJm(-2), including up to 0.314 GJm(-2) of UV irradiation. In a previous study, X. elegans demonstrated considerable resistance towards these conditions by means of photosynthetic activity as well as by post-exposure metabolic activity of 50-80% in the algal and 60-90% in the fungal symbiont (Brandt et al. Int J Astrobiol 14(3):411-425, 2015). The two objectives of the present study were complementary: First, to verify the high post-exposure viability by using a qualitative cultivation assay. Second, to characterise the cellular damages by transmission electron microscopy (TEM) which were caused by the space and Mars-analogue exposure conditions of LIFE. Since the algal symbiont of lichens is considered as the more susceptible partner (de Vera and Ott 2010), the analyses focused on the photobiont. The study demonstrated growth and proliferation of the isolated photobiont after all exposure conditions of LIFE. The ultrastructural analysis of the algal cells provided an insight to cellular damages caused by long-term exposure and highlighted that desiccation-induced breakdown of cellular integrity is more pronounced under the more severe space vacuum than under Mars-analogue atmospheric conditions. In conclusion, desiccation-induced damages were identified as a major threat to the photobiont of X. elegans. Nonetheless, a fraction of the photobiont cells remained cultivable after all exposure conditions tested in LIFE.

A prototype for evidence-based pharmaceutical opinions to promote physician-pharmacist communication around deprescribing

PubMed Central

Tannenbaum, Cara

2018-01-01

Context: Interprofessional communication is an effective mechanism for reducing inappropriate prescriptions among older adults. Physicians’ views about which elements are essential for pharmacists to include in an evidence-based pharmaceutical opinion for deprescribing remain unknown. Objective: To develop a prototype for an evidence-based pharmaceutical opinion that promotes physician-pharmacist communication around deprescribing. Methods: A standardized template for an evidence-based pharmaceutical opinion was developed with input from a convenience sample of 32 primary care physicians and 61 primary care pharmacists, recruited from conferences and community settings in Montreal, Canada. Participants were asked to comment on the need for clarifying treatment goals, including personalized patient data and biomarkers, highlighting evidence about drug harms, listing the credibility and source of the recommendations, providing therapeutic alternatives and formalizing official documentation of decision making. The content and format of the prototype underwent revision by community physicians and pharmacists until consensus was reached on a final recommended template. Results: The majority of physicians (84%-97%) requested that the source of the deprescribing recommendations be cited, that alternative management options be provided and that the information be tailored to the patient. Sixteen percent of physicians expressed concern about the information in the opinions being too dense. Pharmacists also questioned the length of the opinion and asked that additional space be provided for the physician’s response. A statement was added making the opinion a valid prescription upon receipt of a signature from physicians. Compared to a nonstandardized opinion, the majority of pharmacists believed the template was easier to use, more evidence based, more time efficient and more likely to lead to deprescribing. Conclusion: Physicians and pharmacists endorsed a standardized template that promotes interprofessional communication for deprescribing (available at https://www.deprescribingnetwork.ca/pharmaceutical-opinions). The outcome of the D-Prescribe trial will determine the effectiveness of these evidence-based pharmaceutical opinions on deprescribing processes and outcomes. Can Pharm J (Ott) 2018;151:xx-xx. PMID:29531631

Multifractal comparison of the extremes of rain rates and integrated vapour content

NASA Astrophysics Data System (ADS)

Gires, Auguste; Ni, Vincent; Bosser, Pierre; Tchiguirinskaia, Ioulia; Schertzer, Daniel

2015-04-01

Rainfall extremes are studied through the analyse of three related fields measured with the help of co-located devices installed in the roof of the Ecole des Ponts ParisTech building: (i) Integrated Water Vapour (IWV); it corresponds the amount of water vapour present in the vertical columns between a GPS ground receiver and corresponding satellites. It is estimated from the time shift between the expected duration the signal needs to reach the receiver (the two positions are known) and the actual one (ii) Rain rate measured by three optical disdrometers of two different types (Campbell Scientific PWS100 and OTT Parsivel2) (iii) Relative humidity measured by a dedicated sensor First the correlations between these quantities during significant events is analysed. It appears that although IWV tends to decrease (vapour condense to form drops that fall) and relative humidity to increase during a rainfall event, it turns out difficult to quantitatively characterize this link. It is possibly due to the fact that the scale gap between a punctual measure for the rain rate and an average over a few km height column for the IWV is too large. Finally the scaling features of these three fields are investigated with the help of the Universal Multifractal framework which has been extensively used to analyse and simulate geophysical fields extremely variable over wide ranges of scales. Only three parameters are used to characterize variability across scales: C1 the mean intermittency, alpha the multifractality index and H the non-conservative exponent. Retrieved features are compared and the notion of maximum observable singularity is used to quantify the extremes of the various fields. Authors acknowledge the financial support of the Interreg IV NEW RainGain project (www.raingain.eu) and the chair "hydrology for resilient cities" sponsored by Véolia, and the Climate-KIC Blue Green Dream project (bgd.org.uk/).

Rain attenuation statistics over millimeter wave bands in South Korea

NASA Astrophysics Data System (ADS)

Shrestha, Sujan; Choi, Dong-You

2017-01-01

Rain induced degradations are significant for terrestrial microwave links operating at frequencies higher than 10 GHz. Paper presents analyses done on rain attenuation and rainfall data for three years between 2013 till 2015, in 3.2 km experimental link of 38 GHz and 0.1 km link at 75 GHz. The less link distance is maintained for 75 GHz operating frequency in order to have better recording of propagation effect as such attenuation induced by rain. OTT Parsivel is used for collection of rain rate database which show rain rate of about 50 mm/h and attenuation values of 20.89 and 28.55 dB are obtained at 0.01% of the time for vertical polarization under 38 and 75 GHz respectively. Prediction models, namely, ITU-R P. 530-16, Da Silva Mello, Moupfouma, Abdulrahman, Lin and differential equation approach are analyzed. This studies help to identify most suitable rain attenuation model for higher microwave bands. While applying ITU-R P. 530-16, the relative error margin of about 3%, 38% and 42% along with 80, 70, 61% were obtained in 0.1%, 0.01% and 0.001% of the time for vertical polarization under 38 and 75 GHz respectively. Interestingly, ITU-R P. 530-16 shows relatively closer estimation to measured rain attenuation at 75 GHz with relatively less error probabilities and additionally, Abdulrahman and ITU-R P. 530-16 results in better estimation to the measured rain attenuation at 38 GHz link. The performance of prominent rain attenuation models are judged with different error matrices as recommended by ITU-R P. 311-15. Furthermore, the efficacy of frequency scaling technique of rain attenuation between links distribution are also discussed. This study shall be useful for making good considerations in rain attenuation predictions for terrestrial link operating at higher frequencies.

The global mean energy balance under cloud-free conditions

NASA Astrophysics Data System (ADS)

Wild, Martin; Hakuba, Maria; Folini, Dois; Ott, Patricia; Long, Charles

2017-04-01

A long standing problem of climate models is their overestimation of surface solar radiation not only under all-sky, but also under clear-sky conditions (Wild et al. 1995, Wild et al. 2006). This overestimation reduced over time in consecutive model generations due to the simulation of stronger atmospheric absorption. Here we analyze the clear sky fluxes of the latest climate model generation from the Coupled Model Intercomparison Project Phase 5 (CMIP5) against an expanded and updated set of direct observations from the Baseline Surface Radiation Network (BSRN). Clear sky climatologies from these sites have been composed based on the Long and Ackermann (2000) clear sky detection algorithm (Hakuba et al. 2017), and sampling issues when comparing with model simulated clear sky fluxes have been analyzed in Ott (2017). Overall, the overestimation of clear sky insolation in the CMIP5 models is now merely 1-2 Wm-2 in the multimodel mean, compared to 4 Wm-2 in CMIP3 and 6 Wm-2 in AMIPII (Wild et al. 2006). Still a considerable spread in the individual model biases is apparent, ranging from -2 Wm-2 to 10 Wm-2 when averaged over 53 globally distributed BSRN sites. This bias structure is used to infer best estimates for present day global mean clear sky insolation, following an approach developped in Wild et al. (2013, 2015, Clim. Dyn.) for all sky fluxes. Thereby the flux biases in the various models are linearly related to their respective global means. A best estimate can then be inferred from the linear regression at the intersect where the bias against the surface observations becomes zero. This way we obtain a best estimate of 247 Wm-2 for the global mean insolation at the Earth surface under cloud free conditions, and a global mean absorbed solar radiation of 214 Wm-2 in the cloud-free atmosphere, assuming a global mean surface albedo of 13.5%. Combined with a best estimate for the net influx of solar radiation at the Top of Atmosphere under cloud free conditions from CERES EBAF of 286 Wm-2, this leaves an amount of 72 Wm-2 absorbed solar radiation in the cloud free atmosphere. The 72 Wm-2 closely match our best estimate for the global mean cloud-free atmospheric absorption in Wild et al. JGR (2006) based on older models and their biases against much fewer direct observation. This indicates that the estimate of global mean solar absorption in the cloud free atmosphere slightly above 70 Wm-2 is fairly robust. In comparison, the global mean solar absorption under all sky conditions was estimated in Wild et al. (2015) at 80 Wm-2 based on the same approach. The difference between the all- and clear-sky absorption represents the cloud radiative effect on the atmospheric absorption, and is thus estimated here to be around 8 Wm-2. This is similar in magnitude to the 11 Wm-2 derived by Hakuba et al. (2017) when averaged over the atmospheric cloud effect determined at 36 BSRN station. We applied the same methodology also for the longwave fluxes. Thereby we obtained a best estimate for the global mean clear sky downward longwave flux at the Earth surface of 214 Wm-2. Together with a surface and TOA upward longwave flux of 398 Wm-2 and 266 Wm-2, respectively, this leaves an atmospheric longwave divergence under clear sky conditions of 182 Wm-2. Selected related references: Hakuba, M. Z., Folini, D., Wild, M., Long, C. N., Schaepman-Strub, G., and Stephens, G.L., 2017: Cloud Effects on Atmospheric Solar Absorption in Light of Most Recent Surface and Satellite Measurements. AIP Conf. Proc. (in press). Ott, P., 2017: Master Thesis at ETH Zurich (in prep.). Wild, M., Ohmura, A., Gilgen, H., and Roeckner, E., 1995: Validation of GCM simulated radiative fluxes using surface observations. J. Climate, 8, 1309-1324. Wild, M., Long, C.N., and Ohmura, A., 2006: Evaluation of clear-sky solar fluxes in GCMs participating in AMIP and IPCC-AR4 from a surface perspective. J. Geophys. Res., 111, D01104, doi:10.1029/2005JD006118. Wild, M., Folini, D., Schär, C., Loeb, N., Dutton, E.G., and König-Langlo, G., 2013: The global energy balance from a surface perspective. Climate Dynamics, 40, 3107-3134. Wild, M., Folini, D., Hakuba, M., Schär, C., Seneviratne, S.I., Kato, S., Rutan, D., Ammann, C., Wood, E.F., and König-Langlo, G., 2015: The energy balance over land and oceans: An assessment based on direct observations and CMIP5 climate models, Climate Dynamics, 3393-3429, 44, DOI 10.1007/s00382-014-2430-z.

High-resolution stable isotope signature of a land-falling atmospheric river in Southern Norway

NASA Astrophysics Data System (ADS)

Weng, Yongbiao; Sodemann, Harald

2017-04-01

Gathering observational evidence of the long-range moisture versus local source contributions remains a scientific challenge, but is critical for understanding how hydrological extremes develop. Moisture transport to the west coast of Norway is often connected to elongated meridional structures of high water vapour flux known as Atmospheric Rivers. It is still an open question how well moisture sources estimated by different numerical models for such events of long-range transport correspond with reality. In this study, we present high resolution stable isotope information collected during a land-falling Atmospheric River in Southern Norway during winter 2016, and analyse the data with the aim to differentiate between moisture source signatures and below-cloud processes affecting the stable isotope composition. The precipitation characterised by a pronounced warm front was sampled manually on a rooftop platform at a 10-20 minute interval during the 24h of the event and later measured by a laser spectrometer (Picarro L2140-i) in the lab for δ18O, δD, and d-excess. Simultaneously, the stable isotope composition of water vapor was continuously measured at high resolution. To that end, ambient air was continuously pumped from a nearby inlet at 25 m above the ground and measured by another laser spectrometer (Picarro L2130-i). Stable water isotope measurements were supplemented by detailed precipitation parameters from a laser disdrometer (OTT Parsivel2), Micro Rain Radar (MRR-2), Total Precipitation Sensor (TPS-3100), and a nearby weather station. Measurements show a signature of two depletion periods in the main stable isotope parameters that are not apparent in precipitation amount and atmospheric temperature measurements. The deuterium excess in rainfall responds differently, with first and increase and then a decrease during these depletion periods. We interpret this as a combined consequence of airmass change, cloud microphysics, and below-cloud effects. Moisture sources identified during the atmospheric river event show a clear transition that points to the need to constrain this kind of analysis by additional stable water isotope observations en route and upstream.

Durability of the beneficial effect of MLC601 (NeuroAiD™) on functional recovery among stroke patients from the Philippines in the CHIMES and CHIMES-E studies.

PubMed

Navarro, Jose C; Chen, Christopher Lh; Lee, Chun F; Gan, Herminigildo H; Lao, Annabelle Y; Baroque, Alejandro C; Hiyadan, John Harold B; Chua, Carlos L; San Jose, Ma Cristina; Advincula, Joel M; Venketasubramanian, Narayanaswamy

2017-04-01

Background and Aim A pre-specified country analysis of subjects from the Philippines in the CHInese Medicine NeuroAiD Efficacy on Stroke recovery (CHIMES) Study showed significantly improved functional and neurological outcomes on MLC601 at month (M) 3. We aimed to assess these effects on long-term functional recovery in the Filipino cohort. Methods The CHIMES-E (extension) Study evaluated subjects who completed three months of randomized placebo-controlled treatment in CHIMES up to two years. Blinding of treatment allocation was maintained and all subjects received standard stroke care and rehabilitation. Modified Rankin Score (mRS) and Barthel Index (BI) were assessed in-person at M3 and by telephone at M6, M12, M18, M24. Odds ratios (OR) with corresponding 95% confidence intervals (CI) for functional recovery using ordinal analysis of mRS and for achieving functional independence (mRS 0-1 or BI ≥ 95) at each time point were calculated, adjusting for age, sex, baseline National Institute of Health Stroke Scale (NIHSS), onset-to-treatment time (OTT) and pre-stroke mRS. Results The 378 subjects (MLC601 192, placebo 186) included in CHIMES-E from the Philippines (mean age 60.2 ± 11.1) had more women ( p < 0.001), worse baseline NIHSS ( p < 0.001) and longer onset to treatment time ( p = 0.002) compared to other countries. Baseline characteristics were similar between treatment groups. The treatment effect of MLC601 seen at M3 peaked at M6 with OR for mRS shift of 1.53 (95% CI 1.05-2.22), mRS dichotomy 0-1 of 1.77 (95% CI 1.10-2.83), and BI ≥ 95 of 1.87 (95% CI 1.16-3.02). The beneficial effect persisted up to M24. Conclusion The beneficial effect of MLC601 seen at M3 in the Filipino cohort is durable up to two years after stroke.

Flow status of three transboundary rivers in Northern Greece as a tool for hydro-diplomacy

NASA Astrophysics Data System (ADS)

Hatzigiannakis, Eyaggelos; Hatzispiroglou, Ioannis; Arampatzis, Georgios; Ilia, Andreas; Pantelakis, Dimitrios; Filintas, Agathos; Panagopoulos, Andreas

2015-04-01

The aim of this paper is to examine how the river flow monitoring consists a tool for hydro-diplomacy. Management of transboundary catchments and the demand of common water resources, often comprise the cause of conflicts and tension threatening the peaceful coexistence of nations. The Water Framework Directive 2000/60/EU sets a base for water management contributing to common approaches, common goals, common principles as well as providing new definitions and measures for Europe's water resources. In northern Greece the main renewable resources are "imported" (over 25% of its water reserves) and for this reason the implementation of continuous flow measurements throughout the year is necessary, even though difficult to achieve. This paper focuses on the three largest transboundary rivers in Northern Greece. Axios and Strymonas river flow across the region of Central Macedonia in Northern Greece. Axios flows from FYROM to Greece, and Strymonas from Bulgaria to Greece. Nestos river flows from Bulgaria to Greece. The Greek part is in the region of Eastern Macedonia and Thrace in Northern Greece. Significant productive agricultural areas around these rivers are irrigated from them so they are very important for the local society. Measurements of the river flow velocity and the flow depth have been made at bridges. The frequency of the measurements is roughly monthly, because it is expected a significant change in the depth flow and discharge. A series of continuously flow measure-ments were performed during 2013 and 2014 using flowmeters (Valeport and OTT type). The cross-section characteristics, the river flow velocity of segments and the mean water flow velocity and discharge total profile were measured and calculated re-spectively. Measurements are conducted in the framework of the national water resources monitoring network, which is realised in compliance to the Water Framework Directive under the supervision and coordination of the Hellenic Ministry for the Environment and Climate Change. This project is elaborated in the framework of the operational program "Environment and Sustainable Development" which is co-funded by the National Strategic Reference Framework (NSRF) and the Public Investment Program (PIP).

Vertical Variability of Rain Drop Size Distribution from Micro Rain Radar Measurements during IFloodS

NASA Astrophysics Data System (ADS)

Adirosi, Elisa; Tokay, Ali; Roberto, Nicoletta; Gorgucci, Eugenio; Montopoli, Mario; Baldini, Luca

2017-04-01

Ground based weather radars are highly used to generate rainfall products for meteorological and hydrological applications. However, weather radar quantitative rainfall estimation is obtained at a certain altitude that depends mainly on the radar elevation angle and on the distance from the radar. Therefore, depending on the vertical variability of rainfall, a time-height ambiguity between radar measurement and rainfall at the ground can affect the rainfall products. The vertically pointing radars (such as the Micro Rain Radar, MRR) are great tool to investigate the vertical variability of rainfall and its characteristics and ultimately, to fill the gap between the ground level and the first available radar elevation. Furthermore, the knowledge of rain Drop Size Distribution (DSD) variability is linked to the well-known problem of the non-uniform beam filling that is one of the main uncertainties of Global Precipitation Measurement (GPM) mission Dual frequency Precipitation Radar (DPR). During GPM Ground Validation Iowa Flood Studies (IFloodS) field experiment, data collected with 2D video disdrometers (2DVD), Autonomous OTT Parsivel2 Units (APU), and MRR profilers at different sites were available. In three different sites co-located APU, 2DVD and MRR are available and covered by the S-band Dual Polarimetric Doppler radar (NPOL). The first elevation height of the radar beam varies, among the three sites, between 70 m and 1100 m. The IFloodS set-up has been used to compare disdrometers, MRR and NPOL data and to evaluate the uncertainties of those measurements. First, the performance of disdrometers and MRR in determining different rainfall parameters at ground has been evaluated and then the MRR based parameters have been compared with the ones obtained from NPOL data at the lowest elevations. Furthermore, the vertical variability of DSD and integral rainfall parameters within the MRR bins (from ground to 1085 m each 35 m) has been investigated in order to provide some insight on the variability of the rainfall microphysical characteristics within about 1 km above the ground.

Dynamics of Large Systems of Nonlinearly Evolving Units

NASA Astrophysics Data System (ADS)

Lu, Zhixin

The dynamics of large systems of many nonlinearly evolving units is a general research area that has great importance for many areas in science and technology, including biology, computation by artificial neural networks, statistical mechanics, flocking in animal groups, the dynamics of coupled neurons in the brain, and many others. While universal principles and techniques are largely lacking in this broad area of research, there is still one particular phenomenon that seems to be broadly applicable. In particular, this is the idea of emergence, by which is meant macroscopic behaviors that "emerge" from a large system of many "smaller or simpler entities such that...large entities" [i.e., macroscopic behaviors] arise which "exhibit properties the smaller/simpler entities do not exhibit." In this thesis we investigate mechanisms and manifestations of emergence in four dynamical systems consisting many nonlinearly evolving units. These four systems are as follows. (a) We first study the motion of a large ensemble of many noninteracting particles in a slowly changing Hamiltonian system that undergoes a separatrix crossing. In such systems, we find that separatrix-crossing induces a counterintuitive effect. Specifically, numerical simulation of two sets of densely sprinkled initial conditions on two energy curves appears to suggest that the two energy curves, one originally enclosing the other, seemingly interchange their positions. This, however, is topologically forbidden. We resolve this paradox by introducing a numerical simulation method we call "robust" and study its consequences. (b) We next study the collective dynamics of oscillatory pacemaker neurons in Suprachiasmatic Nucleus (SCN), which, through synchrony, govern the circadian rhythm of mammals. We start from a high-dimensional description of the many coupled oscillatory neuronal units within the SCN. This description is based on a forced Kuramoto model. We then reduce the system dimensionality by using the Ott Antonsen Ansatz and obtain a low-dimensional macroscopic description. Using this reduced macroscopic system, we explain the east-west asymmetry of jet-lag recovery and discus the consequences of our findings. (c) Thirdly, we study neuron firing in integrate-and-fire neural networks. We build a discrete-state/discrete-time model with both excitatory and inhibitory neurons and find a phase transition between avalanching dynamics and ceaseless firing dynamics. Power-law firing avalanche size/duration distributions are observed at critical parameter values. Furthermore, in this critical regime we find the same power law exponents as those observed from experiments and previous, more restricted, simulation studies. We also employ a mean-field method and show that inhibitory neurons in this system promote robustness of the criticality (i.e., an enhanced range of system parameter where power-law avalanche statistics applies). (d) Lastly, we study the dynamics of "reservoir computing networks" (RCN's), which is a recurrent neural network (RNN) scheme for machine learning. The advantage of RCN's over traditional RNN's is that the training is done only on the output layer, usually via a simple least-square method. We show that RCN's are very effective for inferring unmeasured state variables of dynamical systems whose system state is only partially measured. Using the examples of the Lorenz system and the Rossler system we demonstrate the potential of an RCN to perform as an universal model-free "observer".

Application of Bred Vectors To Data Assimilation

NASA Astrophysics Data System (ADS)

Corazza, M.; Kalnay, E.; Patil, Dj

We introduced a statistic, the BV-dimension, to measure the effective local finite-time dimensionality of the atmosphere. We show that this dimension is often quite low, and suggest that this finding has important implications for data assimilation and the accuracy of weather forecasting (Patil et al, 2001). The original database for this study was the forecasts of the NCEP global ensemble forecasting system. The initial differences between the control forecast and the per- turbed forecasts are called bred vectors. The control and perturbed initial conditions valid at time t=n(t are evolved using the forecast model until time t=(n+1) (t. The differences between the perturbed and the control forecasts are scaled down to their initial amplitude, and constitute the bred vectors valid at (n+1) (t. Their growth rate is typically about 1.5/day. The bred vectors are similar by construction to leading Lya- punov vectors except that they have small but finite amplitude, and they are valid at finite times. The original NCEP ensemble data set has 5 independent bred vectors. We define a local bred vector at each grid point by choosing the 5 by 5 grid points centered at the grid point (a region of about 1100km by 1100km), and using the north-south and east- west velocity components at 500mb pressure level to form a 50 dimensional column vector. Since we have k=5 global bred vectors, we also have k local bred vectors at each grid point. We estimate the effective dimensionality of the subspace spanned by the local bred vectors by performing a singular value decomposition (EOF analysis). The k local bred vector columns form a 50xk matrix M. The singular values s(i) of M measure the extent to which the k column unit vectors making up the matrix M point in the direction of v(i). We define the bred vector dimension as BVDIM={Sum[s(i)]}^2/{Sum[s(i)]^2} For example, if 4 out of the 5 vectors lie along v, and one lies along v, the BV- dimension would be BVDIM[sqrt(4), 1, 0,0,0]=1.8, less than 2 because one direction is more dominant than the other in representing the original data. The results (Patil et al, 2001) show that there are large regions where the bred vectors span a subspace of substantially lower dimension than that of the full space. These low dimensionality regions are dominant in the baroclinic extratropics, typically have a lifetime of 3-7 days, have a well-defined horizontal and vertical structure that spans 1 most of the atmosphere, and tend to move eastward. New results with a large number of ensemble members confirm these results and indicate that the low dimensionality regions are quite robust, and depend only on the verification time (i.e., the underlying flow). Corazza et al (2001) have performed experiments with a data assimilation system based on a quasi-geostrophic model and simulated observations (Morss, 1999, Hamill et al, 2000). A 3D-variational data assimilation scheme for a quasi-geostrophic chan- nel model is used to study the structure of the background error and its relationship to the corresponding bred vectors. The "true" evolution of the model atmosphere is defined by an integration of the model and "rawinsonde observations" are simulated by randomly perturbing the true state at fixed locations. It is found that after 3-5 days the bred vectors develop well organized structures which are very similar for the two different norms considered in this paper (potential vorticity norm and streamfunction norm). The results show that the bred vectors do indeed represent well the characteristics of the data assimilation forecast errors, and that the subspace of bred vectors contains most of the forecast error, except in areas where the forecast errors are small. For example, the angle between the 6hr forecast error and the subspace spanned by 10 bred vectors is less than 10o over 90% of the domain, indicating a pattern correlation of more than 98.5% between the forecast error and its projection onto the bred vector subspace. The presence of low-dimensional regions in the perturbations of the basic flow has important implications for data assimilation. At any given time, there is a difference between the true atmospheric state and the model forecast. Assuming that model er- rors are not the dominant source of errors, in a region of low BV-dimensionality the difference between the true state and the forecast should lie substantially in the low dimensional unstable subspace of the few bred vectors that contribute most strongly to the low BV-dimension. This information should yield a substantial improvement in the forecast: the data assimilation algorithm should correct the model state by moving it closer to the observations along the unstable subspace, since this is where the true state most likely lies. Preliminary experiments have been conducted with the quasi-geostrophic data assim- ilation system testing whether it is possible to add "errors of the day" based on bred vectors to the standard (constant) 3D-Var background error covariance in order to capture these important errors. The results are extremely encouraging, indicating a significant reduction (about 40%) in the analysis errors at a very low computational cost. References: 2 Corazza, M., E. Kalnay, DJ Patil, R. Morss, M Cai, I. Szunyogh, BR Hunt, E Ott and JA Yorke, 2001: Use of the breeding technique to estimate the structure of the analysis "errors of the day". Submitted to Nonlinear Processes in Geophysics. Hamill, T.M., Snyder, C., and Morss, R.E., 2000: A Comparison of Probabilistic Fore- casts from Bred, Singular-Vector and Perturbed Observation Ensembles, Mon. Wea. Rev., 128, 1835­1851. Kalnay, E., and Z. Toth, 1994: Removing growing errors in the analysis cycle. Preprints of the Tenth Conference on Numerical Weather Prediction, Amer. Meteor. Soc., 1994, 212-215. Morss, R. E., 1999: Adaptive observations: Idealized sampling strategies for improv- ing numerical weather prediction. PHD thesis, Massachussetts Institute of technology, 225pp. Patil, D. J. S., B. R. Hunt, E. Kalnay, J. A. Yorke, and E. Ott., 2001: Local Low Dimensionality of Atmospheric Dynamics. Phys. Rev. Lett., 86, 5878. 3

Problems in the Definition, Interpretation, and Evaluation of Genetic Heterogeneity

PubMed Central

Whittemore, Alice S.; Halpern, Jerry

2001-01-01

Suppose that we wish to classify families with multiple cases of disease into one of three categories: those that segregate mutations of a gene of interest, those which segregate mutations of other genes, and those whose disease is due to nonhereditary factors or chance. Among families in the first two categories (the hereditary families), we wish to estimate the proportion, p, of families that segregate mutations of the gene of interest. Although this proportion is a commonly accepted concept, it is well defined only with an unambiguous definition of “family.” Even then, extraneous factors such as family sizes and structures can cause p to vary across different populations and, within a population, to be estimated differently by different studies. Restrictive assumptions about the disease are needed, in order to avoid this undesirable variation. The assumptions require that mutations of all disease-causing genes (i) have no effect on family size, (ii) have very low frequencies, and (iii) have penetrances that satisfy certain constraints. Despite the unverifiability of these assumptions, linkage studies often invoke them to estimate p, using the admixture likelihood introduced by Smith and discussed by Ott. We argue against this common practice, because (1) it also requires the stronger assumption of equal penetrances for all etiologically relevant genes; (2) even if all assumptions are met, estimates of p are sensitive to misspecification of the unknown phenocopy rate; (3) even if all the necessary assumptions are met and the phenocopy rate is correctly specified, estimates of p that are obtained by linkage programs such as HOMOG and GENEHUNTER are based on the wrong likelihood and therefore are biased in the presence of phenocopies. We show how to correct these estimates; but, nevertheless, we do not recommend the use of parametric heterogeneity models in linkage analysis, even merely as a tool for increasing the statistical power to detect linkage. This is because the assumptions required by these models cannot be verified, and their violation could actually decrease power. Instead, we suggest that estimation of p be postponed until the relevant genes have been identified. Then their frequencies and penetrances can be estimated on the basis of population-based samples and can be used to obtain more-robust estimates of p for specific populations. PMID:11170893

A laboratory assessment of the measurement accuracy of weighing type rainfall intensity gauges

NASA Astrophysics Data System (ADS)

Colli, M.; Chan, P. W.; Lanza, L. G.; La Barbera, P.

2012-04-01

In recent years the WMO Commission for Instruments and Methods of Observation (CIMO) fostered noticeable advancements in the accuracy of precipitation measurement issue by providing recommendations on the standardization of equipment and exposure, instrument calibration and data correction as a consequence of various comparative campaigns involving manufacturers and national meteorological services from the participating countries (Lanza et al., 2005; Vuerich et al., 2009). Extreme events analysis is proven to be highly affected by the on-site RI measurement accuracy (see e.g. Molini et al., 2004) and the time resolution of the available RI series certainly constitutes another key-factor in constructing hyetographs that are representative of real rain events. The OTT Pluvio2 weighing gauge (WG) and the GEONOR T-200 vibrating-wire precipitation gauge demonstrated very good performance under previous constant flow rate calibration efforts (Lanza et al., 2005). Although WGs do provide better performance than more traditional Tipping Bucket Rain gauges (TBR) under continuous and constant reference intensity, dynamic effects seem to affect the accuracy of WG measurements under real world/time varying rainfall conditions (Vuerich et al., 2009). The most relevant is due to the response time of the acquisition system and the derived systematic delay of the instrument in assessing the exact weight of the bin containing cumulated precipitation. This delay assumes a relevant role in case high resolution rain intensity time series are sought from the instrument, as is the case of many hydrologic and meteo-climatic applications. This work reports the laboratory evaluation of Pluvio2 and T-200 rainfall intensity measurements accuracy. Tests are carried out by simulating different artificial precipitation events, namely non-stationary rainfall intensity, using a highly accurate dynamic rainfall generator. Time series measured by an Ogawa drop counter (DC) at a field test site located within the Hong Kong International Airport (HKIA) were aggregated at a 1-minute scale and used as reference for the artificial rain generation (Colli et al., 2012). The preliminary development and validation of the rainfall simulator for the generation of variable time steps reference intensities is also shown. The generator is characterized by a sufficiently short time response with respect to the expected weighing gauges behavior in order to ensure effective comparison of the measured/reference intensity at very high resolution in time.

Variation of rain intensity and drop size distribution with General Weather Patterns (GWL)

NASA Astrophysics Data System (ADS)

Ghada, Wael; Buras, Allan; Lüpke, Marvin; Menzel, Annette

2017-04-01

Short-duration rainfall extremes may cause flash floods in certain catchments (e.g. cities or fast responding watersheds) and pose a great risk to affected communities. In order to predict their occurrence under future climate change scenarios, their link to atmospheric circulation patterns needs to be well understood. We used a comprehensive data set of meteorological data (temperature, rain gauge precipitation) and precipitation spectra measured by a disdrometer (OTT PARSIVEL) between October 2008 and June 2010 at Freising, southern Germany. For the 21 months of the study period, we integrated the disdrometer spectra over intervals of 10 minutes to correspond to the temporal resolution of the weather station data and discarded measurements with air temperatures below 0°C. Daily General Weather Patterns ("Großwetterlagen", GWL) were downloaded from the website of the German Meteorological Service. Out of the 29 GWL, 14 were included in the analysis for which we had at least 12 rain events during our study period. For the definition of a rain event, we tested different lengths of minimum inter-event times and chose 30 min as a good compromise between number and length of resulting events; rain events started when more than 0.001 mm/h (sensitivity of the disdrometer) were recorded. The length of the rain events ranged between 10 min and 28 h (median 130 min) with the maximum rain intensity recorded being 134 mm/h on 24-07-2009. Seasonal differences were identified for rain event average intensities and maximum intensities per event. The influence of GWL on rain properties such as rain intensity and drop size distribution per time step and per event was investigated based on the above mentioned rain event definition. Pairwise Wilcoxon-tests revealed that higher rain intensity and larger drops were associated with the GWL "Low over the British Isles" (TB), whereas low rain intensities and less drops per interval were associated with the GWL "High over Central Europe" (HM). "Trough over Central Europe" (TRM) was linked to smaller drops and "High Scandinavia-Iceland, Trough C. Europe" (HNFZ) had fewer drops per time step when compared to other GWL types. We also investigated the intra-event behavior regarding fluctuations in rain intensity, rain drop counts, and drop size distribution with time. When combined with predictions of circulation patterns, our analysis provides a detailed insight into the characteristics of rain events under different future climate scenarios, but definitively an extended measurement period and more measurement locations are needed for validation.

Study of rain attenuation in Ka band for satellite communication in South Korea

NASA Astrophysics Data System (ADS)

Shrestha, Sujan; Choi, Dong-You

2016-10-01

The important factor to be considered in the link budget estimation for satellite communication systems, operating at frequencies above 10 GHz is the rain attenuation. Scattering and absorption are the main concern for system designers at these frequency bands. This has resulted in the need for suitable prediction models that can best provide estimates of attenuation due to rain with available information of rain attenuation data. Researchers have developed models that can be used to estimate 1-min rainfall attenuation distribution for earth space link but there is still some confusion with regard to choosing the right model to predict attenuation for the location of interest. In this context, the existing prediction models need to be tested against the measured results. This paper presents studies on rain attenuation at 19.8 GHz, which specifies the performance parameters for Ka-Band under earth space communication system. It presents the experimental result of rain rates and rain-induced attenuation in 19.8 and 20.73 GHz for vertical and circular polarization respectively. The received signal data for rain attenuation and rain rate were collected at 10 s intervals over a three year periods from 2013 to 2015. The data highlights the impact of clear air variation and rain fade loss. Rain rate data was measured through OTT Parsivel. During the observation period, rain rates of about 50 mm/h and attenuation values of 11.6 dB for 0.01% of the time were noted. The experimental link was set up at Korea Radio Promotion Association, Mokdong, Seoul. Out of several models, this paper present discussion and comparison of ITU-R P.618-12, Unified Method, Dissanayake Allnutt and Haidara (DAH), Simple Attenuation (SAM), Crane Global and Ramachandran and Kumar models. The relative error margin of 27.51, 89.84,72.46% and 67.24, 130.84, 166.48% are obtained for 0.1%, 0.01% and 0.001% of the time for 19.8 and 20.73 GHz under vertical and circular polarization respectively from ITU-R P. 618-12 method which has been analyzed in the further section of this article. In order to obtain the better approximation of rain induced attenuation, the suitable method is proposed for earth space link whose efficiency have been compared with prominent rain attenuation models. The method provides useful information for system engineers and researchers in making a decision over the choice of suitable rain attenuation prediction method for earth space communication operating in the South Korea region.

Moderate Hypofractionated Protracted Radiation Therapy and Dose Escalation for Prostate Cancer: Do Dose and Overall Treatment Time Matter?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kountouri, Melpomeni; Zilli, Thomas; Rouzaud, Michel

2016-02-01

Purpose: This was a retrospective study of 2 sequential dose escalation regimens of twice-weekly 4 Gy/fractions hypofractionated intensity modulated radiation therapy (IMRT): 56 Gy and 60 Gy delivered within a protracted overall treatment time (OTT) of 6.5 and 7 weeks, respectively. Methods and Materials: 163 prostate cancer patients with cT1c-T3a disease and nodal involvement risk ≤20% (Roach index) were treated twice weekly to the prostate ± seminal vesicles with 2 sequential dose-escalated IMRT schedules: 56 Gy (14 × 4 Gy, n=81) from 2003 to 2007 and 60 Gy (15 × 4 Gy, n=82) from 2006 to 2010. Patient repositioning was made with bone matching on portal images. Gastrointestinal (GI) and genitourinary (GU) toxicities weremore » scored according to the Common Terminology Criteria for Adverse Events version 3.0 grading scale. Results: There were no significant differences regarding the acute GU and GI toxicities in the 2 dose groups. The median follow-up times were 80.2 months (range, 4.5-121 months) and 56.5 months (range, 1.4-91.2 months) for patients treated to 56 and 60 Gy, respectively. The 5-year grade ≥2 late GU toxicity-free survivals with 56 Gy and 60 Gy were 96 ± 2.3% and 78.2 ± 5.1% (P=.001), respectively. The 5-year grade ≥2 late GI toxicity-free survivals with 56 Gy and 60 Gy were 98.6 ± 1.3% and 85.1 ± 4.5% (P=.005), respectively. Patients treated with 56 Gy showed a 5-year biochemical progression-free survival (bPFS) of 80.8 ± 4.7%, worse than patients treated with 60 Gy (93.2 ± 3.9%, P=.007). A trend for a better 5-year distant metastasis-free survival was observed among patients treated in the high-dose group (95.3 ± 2.7% vs 100%, P=.073, respectively). On multivariate analysis, only the 60-Gy group predicted for a better bPFS (P=.016, hazard ratio = 4.58). Conclusions: A single 4-Gy additional fraction in patients treated with a hypofractionated protracted IMRT schedule of 14 × 4 Gy resulted in a similar and minimal acute toxicity, in worse moderate to severe urinary and GI late effects, but a significantly better biochemical control.« less

Agile Acceptance Test-Driven Development of Clinical Decision Support Advisories: Feasibility of Using Open Source Software.

PubMed

Basit, Mujeeb A; Baldwin, Krystal L; Kannan, Vaishnavi; Flahaven, Emily L; Parks, Cassandra J; Ott, Jason M; Willett, Duwayne L

2018-04-13

Moving to electronic health records (EHRs) confers substantial benefits but risks unintended consequences. Modern EHRs consist of complex software code with extensive local configurability options, which can introduce defects. Defects in clinical decision support (CDS) tools are surprisingly common. Feasible approaches to prevent and detect defects in EHR configuration, including CDS tools, are needed. In complex software systems, use of test-driven development and automated regression testing promotes reliability. Test-driven development encourages modular, testable design and expanding regression test coverage. Automated regression test suites improve software quality, providing a "safety net" for future software modifications. Each automated acceptance test serves multiple purposes, as requirements (prior to build), acceptance testing (on completion of build), regression testing (once live), and "living" design documentation. Rapid-cycle development or "agile" methods are being successfully applied to CDS development. The agile practice of automated test-driven development is not widely adopted, perhaps because most EHR software code is vendor-developed. However, key CDS advisory configuration design decisions and rules stored in the EHR may prove amenable to automated testing as "executable requirements." We aimed to establish feasibility of acceptance test-driven development of clinical decision support advisories in a commonly used EHR, using an open source automated acceptance testing framework (FitNesse). Acceptance tests were initially constructed as spreadsheet tables to facilitate clinical review. Each table specified one aspect of the CDS advisory's expected behavior. Table contents were then imported into a test suite in FitNesse, which queried the EHR database to automate testing. Tests and corresponding CDS configuration were migrated together from the development environment to production, with tests becoming part of the production regression test suite. We used test-driven development to construct a new CDS tool advising Emergency Department nurses to perform a swallowing assessment prior to administering oral medication to a patient with suspected stroke. Test tables specified desired behavior for (1) applicable clinical settings, (2) triggering action, (3) rule logic, (4) user interface, and (5) system actions in response to user input. Automated test suite results for the "executable requirements" are shown prior to building the CDS alert, during build, and after successful build. Automated acceptance test-driven development and continuous regression testing of CDS configuration in a commercial EHR proves feasible with open source software. Automated test-driven development offers one potential contribution to achieving high-reliability EHR configuration. Vetting acceptance tests with clinicians elicits their input on crucial configuration details early during initial CDS design and iteratively during rapid-cycle optimization. ©Mujeeb A Basit, Krystal L Baldwin, Vaishnavi Kannan, Emily L Flahaven, Cassandra J Parks, Jason M Ott, Duwayne L Willett. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 13.04.2018.

A laboratory evaluation of the influence of weighing gauges performance on extreme events statistics

NASA Astrophysics Data System (ADS)

Colli, Matteo; Lanza, Luca

2014-05-01

The effects of inaccurate ground based rainfall measurements on the information derived from rain records is yet not much documented in the literature. La Barbera et al. (2002) investigated the propagation of the systematic mechanic errors of tipping bucket type rain gauges (TBR) into the most common statistics of rainfall extremes, e.g. in the assessment of the return period T (or the related non-exceedance probability) of short-duration/high intensity events. Colli et al. (2012) and Lanza et al. (2012) extended the analysis to a 22-years long precipitation data set obtained from a virtual weighing type gauge (WG). The artificial WG time series was obtained basing on real precipitation data measured at the meteo-station of the University of Genova and modelling the weighing gauge output as a linear dynamic system. This approximation was previously validated with dedicated laboratory experiments and is based on the evidence that the accuracy of WG measurements under real world/time varying rainfall conditions is mainly affected by the dynamic response of the gauge (as revealed during the last WMO Field Intercomparison of Rainfall Intensity Gauges). The investigation is now completed by analyzing actual measurements performed by two common weighing gauges, the OTT Pluvio2 load-cell gauge and the GEONOR T-200 vibrating-wire gauge, since both these instruments demonstrated very good performance under previous constant flow rate calibration efforts. A laboratory dynamic rainfall generation system has been arranged and validated in order to simulate a number of precipitation events with variable reference intensities. Such artificial events were generated basing on real world rainfall intensity (RI) records obtained from the meteo-station of the University of Genova so that the statistical structure of the time series is preserved. The influence of the WG RI measurements accuracy on the associated extreme events statistics is analyzed by comparing the original intensity-duration-frequency (IDF) curves with those obtained from the measuring of the simulated rain events. References: Colli, M., L.G. Lanza, and P. La Barbera, (2012). Weighing gauges measurement errors and the design rainfall for urban scale applications, 9th International Workshop On Precipitation In Urban Areas, 6-9 December, 2012, St. Moritz, Switzerland Lanza, L.G., M. Colli, and P. La Barbera (2012). On the influence of rain gauge performance on extreme events statistics: the case of weighing gauges, EGU General Assembly 2012, April 22th, Wien, Austria La Barbera, P., L.G. Lanza, and L. Stagi, (2002). Influence of systematic mechanical errors of tipping-bucket rain gauges on the statistics of rainfall extremes. Water Sci. Techn., 45(2), 1-9.

Investigations on the links between rain intensity or reflectivity structures estimated from radar and drop size distributions

NASA Astrophysics Data System (ADS)

Hachani, Sahar; Boudevillain, Brice; Bargaoui, Zoubeida; Delrieu, Guy

2015-04-01

During the first Special Observation Period (SOP) of the Hydrological cycle in the Mediterranean Experiment (HyMeX, www.hymex.org) held in fall 2012 in the Northwestern Mediterranean region, an observation network dedicated to rain studies was implemented in the Cévennes region, France. It was mainly constituted by weather radars, micro rain radars, disdrometers and rain gauges. Observations are performed by a network of 25 OTT Parsivel optical disdrometers distributed with inter-distances ranging from a few meters up to about one hundred kilometers. This presentation focuses on the comparison of one optical disdrometer observations located at Villeneuve-de-berg to observations using weather Météo-France / ARAMIS radar located at Bollène which is in a neighborhood of 60 km from the disdrometer.The period from September to November 2012 is studied. To analyze the structure of the rain observed by radar, a window of investigation centered on the disdrometer was selected and the mean spatial values, standard deviation, gradients, and intermittency of radar reflectivity or rainfall intensity were computed for a time step of 5 minutes.Four different windowsizes were analyzed: 1 km², 25 km², 100 km² and 400 km². On the other hand, the total concentration of drops Nt, the characteristic diameter of drops Dc, and a Gamma distribution shape parameter µ were estimated. Gamma distribution for the DSD related to disdrometer observations was estimated according to the modeling framework proposed by Yu et al. (2014). Correlation coefficient between intensity R obtained by the disdrometer and windowaverage R estimated using radar data is nearly 0.70 whatever the window. The highest value is found for the window 25 km² (0.74). Correlation coefficients between Dc and window average R vary from 0.35 for the window 1 km² to 0.4 for the window 400 km². So, they areweak and not sensitive to the choice of the window. Contrarily, formean radar reflectivityZ, correlation coefficients with Dc, Nt and µ vary to some extent from the window size 1 km² to the window size 100 km². The most sensitive is the correlation coefficient between Z and Nt. However it presents the smallest correlations while the highest correlations are found for Dc (respectively 0.80 and 0.74). The overall of relations between the rainfall structure variables and DSD parameters will be presented in the communication with a special attention to the weather and/or rainfall types (orographic, stratiform, and convective). References: Yu, N., Delrieu, G., Boudevillain, B., Hazenberg, P., and Uijlenhoet, R., 2014: Unified formulation of single and multi-moment normalizations of the raindrop size distribution based on the gamma probability density function. Journal of Applied Meteorology and Climatology, 53, pp 166-179.

Linking varve-formation processes to climate and lake conditions at Tiefer See (NE Germany)

NASA Astrophysics Data System (ADS)

Dräger, Nadine; Kienel, Ulrike; Plessen, Birgit; Ott, Florian; Brademann, Brian; Pinkerneil, Sylvia; Brauer, Achim

2017-04-01

Annually laminated (varved) lake sediments represent unique archives in continental areas providing both, precise chronologies and seasonally resolving proxy data. Monitoring of physical, chemical and biological processes influencing lake sediment formation are a suitable approach for detailed proxy understanding of varved sediment records. Lake Tiefer See (NE Germany) indicates deposition of varved sediments today as well as millennia ago (Dräger et al., 2016; Kienel et al., 2013). Therefore, the lake provides the possibility to trace current seasonal layer formation in the lake and to pair these data to climate and lake conditions (Kienel et al., 2016). Lake Tiefer See was formed during the last glaciation and is part of the Klocksin Lake Chain, a subglacial channel system that crosses the Pomeranian terminal moraine. The lake is a mesotrophic hard water lake with a maximum depth of 63 m and a surface area of 0.75 km2. During four consecutive years (2012-2015) the particulate matter deposition was trapped at bi-weekly to monthly resolution at three different water depths (5, 12 and 50 m). The sediment trap material was analysed for sediment flux and organic matter and calcite content. In addition, we monitored limnological parameters (e.g. temperature, pH, conductivity, oxygen content) as well as the meteorological conditions (e.g. temperature, wind speed and direction, precipitation) with a monitoring and climate station installed on the lake. These data describe strength and duration of lake mixing and lake stagnation phases. Our results show distinct seasonal peaks in sediment formation, which correspond to the spring and summer productivity phases comprising of diatom blooms and calcite precipitation. This observation is in line with microfacies results from surface sediment cores. The content of biogenic calcite content decreases in the trapped material with increasing water depth indicating dissolution processes. However, the strength of calcite dissolution varies between seasons and years. We will discuss the depositional processes in relation to conditions in the water column and to meteorological data. This study is a contribution to the Virtual Institute of Integrated Climate and Landscape Evolution Analysis -ICLEA- of the Helmholtz Association; grant number VH-VI-415. Dräger N, Brauer A, Theuerkauf M, Szeroczyńska K, Tjallingii R, Plessen B, Kienel U and Brauer A (2016) A varve micro-facies and varve preservation record of climate change and human impact for the last 6000 years at Lake Tiefer See (NE Germany). The Holocene online first. Kienel U, Dulski P, Ott F, Lorenz S and Brauer A (2013) Recently induced anoxia leading to the preservation of seasonal laminae in two NE-German lakes. Journal of paleolimnology 50 (4): 535-544. Kienel U, Kirillin G, Brademann B, Plessen B, Lampe R and Brauer A (2016) Effects of spring warming and mixing duration on diatom deposition in deep Tiefer See, NE Germany. Journal of paleolimnology 57 (1): 37-49.

Ozone retrievals from MAGEAQ GEO TIR+VIS for air quality

NASA Astrophysics Data System (ADS)

Quesada-Ruiz, Samuel; Attié, Jean-Luc; Lahoz, William A.; Abida, Rachid; El-Amraoui, Laaziz; Ricaud, Philippe; Zbinden, Regina; Spurr, Robert; da Silva, Arlindo M.

2016-04-01

Nowadays, air quality monitoring is based on the use of ground-based stations (GBS) or satellite measurements. GBS provide accurate measurements of pollutant concentrations, especially in the planetary boundary layer (PBL), but usually the spatial coverage is sparse. Polar-orbiting satellites provide good spatial resolution but low temporal coverage -this is insufficient for tracking pollutants exhibiting a diurnal cycle (Lahoz et al., 2012). However, pollutant concentrations can be measured by instruments placed on board a geostationary satellite, which can provide sufficiently high temporal and spatial resolutions (e.g. Hache et al., 2014). In this work, we investigate the potentiality of a possible future geostationary instrument, MAGEAQ (Monitoring the Atmosphere from Geostationary orbit for European Air Quality), for retrieving ozone measurements over Europe. In particular, MAGEAQ can provide 1-hour temporal sampling at 10x10km pixel resolution for measurements in both visible (VIS) and thermal infrared (TIR) bands -thus, we will be able to measure during the day and at night. MAGEAQ synthetic radiance observations are obtained through radiative transfer (RT) simulations using the VLIDORT discrete ordinate RT model (Spurr, 2006) based on output from the GEOS-5 Nature Run (Gelaro et al., 2015) providing optical information, plus a suitable instrument model. Ozone is retrieved from these synthetic measurements using the optimal estimation inversion scheme of Levenberg-Marquardt. Finally, we examine an application of the air quality concept based on these ozone retrievals during the heatwave event of July 2006 over Europe. REFERENCES Gelaro, R., Putman, W. M., Pawson, S., Draper, C., Molod, A., Norris, P. M., Ott, L., Privé, N., Reale, O., Achuthavarier, D., Bosilovich, M., Buchard, V., Chao, W., Coy, L., Cullather, R., da Silva, A., Darmenov, A., Errico, R. M., Fuentes, M., Kim, M-J., Koster, R., McCarty, W., Nattala, J., Partyka, G., Schubert, S., Vernieres, G., Vikhliaev, Y., and Wargan, K.. Evaluation of the 7-km GEOS-5 Nature Run. NASA/TM-2014-104606, Vol. 36., 2015. Hache, E., Attié, J.L., Tourneur, C., Ricaud, P., Coret, L., Lahoz, W.A., El Amraoui, L., Josse, B., Hamer, P., Warner, J., Liu, X., Chance, K., Höpfner, M., Spurr, R., Natraj, V., Kulawik, S., Eldering, A. and Orphal, J.. The added value of a visible channel to a geostationary thermal infrared instrument to monitor ozone for air quality. Atmos. Meas. Tech., 7, 2185-2201, 2014. Lahoz, W. A., Peuch, V. H., Orphal, J., Attie, J.L., Chance, K., Liu, X., Edwards, D., Elbern, H., Flaud, J. M., Claeyman, M., and El Amraoui, L.. Monitoring Air Quality from Space: The Case for the Geostationay Platform. Bulletin of the American Meteorological Society, 93, 221-233, 2012. Spurr, R. J. D.. VLIDORT: A Linearized Pseudo-Spherical Vector Discrete Ordinate Radiative Transfer Code for Forward Model and Retrieval Studies in Multilayer Multiple Scattering Media. Journal of Quantitative Spectroscopy & Radiative Transfer, 102, 316-342, 2006.

Collective Dynamics for Heterogeneous Networks of Theta Neurons

NASA Astrophysics Data System (ADS)

Luke, Tanushree

Collective behavior in neural networks has often been used as an indicator of communication between different brain areas. These collective synchronization and desynchronization patterns are also considered an important feature in understanding normal and abnormal brain function. To understand the emergence of these collective patterns, I create an analytic model that identifies all such macroscopic steady-states attainable by a network of Type-I neurons. This network, whose basic unit is the model "theta'' neuron, contains a mixture of excitable and spiking neurons coupled via a smooth pulse-like synapse. Applying the Ott-Antonsen reduction method in the thermodynamic limit, I obtain a low-dimensional evolution equation that describes the asymptotic dynamics of the macroscopic mean field of the network. This model can be used as the basis in understanding more complicated neuronal networks when additional dynamical features are included. From this reduced dynamical equation for the mean field, I show that the network exhibits three collective attracting steady-states. The first two are equilibrium states that both reflect partial synchronization in the network, whereas the third is a limit cycle in which the degree of network synchronization oscillates in time. In addition to a comprehensive identification of all possible attracting macro-states, this analytic model permits a complete bifurcation analysis of the collective behavior of the network with respect to three key network features: the degree of excitability of the neurons, the heterogeneity of the population, and the overall coupling strength. The network typically tends towards the two macroscopic equilibrium states when the neuron's intrinsic dynamics and the network interactions reinforce each other. In contrast, the limit cycle state, bifurcations, and multistability tend to occur when there is competition between these network features. I also outline here an extension of the above model where the neurons' excitability now varies in time sinuosoidally, thus simulating a parabolic bursting network. This time-varying excitability can lead to the emergence of macroscopic chaos and multistability in the collective behavior of the network. Finally, I expand the single population model described above to examine a two-population neuronal network where each population has its own unique mixture of excitable and spiking neurons, as well as its own coupling strength (either excitatory or inhibitory in nature). Specifically, I consider the situation where the first population is only allowed to influence the second population without any feedback, thus effectively creating a feed-forward "driver-response" system. In this special arrangement, the driver's asymptotic macroscopic dynamics are fully explored in the comprehensive analysis of the single population. Then, in the presence of an influence from the driver, the modified dynamics of the second population, which now acts as a response population, can also be fully analyzed. As in the time-varying model, these modifications give rise to richer dynamics to the response population than those found from the single population formalism, including multi-periodicity and chaos.

OAST system technology planning

NASA Technical Reports Server (NTRS)

Sadin, S. R.

1978-01-01

The NASA Office of Aeronautics and Space Technology developed a planning model for space technology consisting of a space systems technology model, technology forecasts and technology surveys. The technology model describes candidate space missions through the year 2000 and identifies their technology requirements. The technology surveys and technology forecasts provide, respectively, data on the current status and estimates of the projected status of relevant technologies. These tools are used to further the understanding of the activities and resources required to ensure the timely development of technological capabilities. Technology forecasting in the areas of information systems, spacecraft systems, transportation systems, and power systems are discussed.

What is technology? A study of fifth and eighth grade student ideas about the Nature of Technology

NASA Astrophysics Data System (ADS)

Digironimo, Nicole

Most, if not all, standards for science and technology education and curriculum indicate that knowledge of the Nature of Technology is an educational goal, yet the literature lacks an established definition for the Nature of Technology. Additionally, the research on student ideas about the Nature of Technology is insufficient. After reviewing the literature on science and technology education, the philosophy of technology, and the history of technology, this study presents an internally consistent definition for the Nature of Technology. This definition illustrates how the Nature of Technology includes five dimensions: Technology as Artifacts; Technology as a Creation Process; Technology as a Human Practice; The History of Technology; and The Current Role of Technology. Using an interview protocol developed for this study, a small group of 5th and 8th grade students were interviewed to ascertain their ideas about the Nature of Technology. The results indicate that there are a variety of ideas present in the thinking of young people. All of the participants expressed one of two ideas about technological artifacts: technological artifacts are electronic or technological artifacts are invented. All of the participants identified particular skills needed to invent technological artifacts; some of the participants included mobility and concluded that disabled people cannot be inventors. Despite their experiences with technological artifacts (including educational technology tools), a few of the participants were uncertain whether they would identify themselves as technological. More than half of the participants did not believe older artifacts can still be considered technology. Most of the participants were apprehensive about our technological future; the main issue expressed by the participants was the environment. Other than environmental concerns, most of the participants were unable to identify global issues regarding technological use and development. Overall, these findings increase our knowledge of the ideas young people have about the Nature of Technology, which can inform future research on teaching and learning about science and technology.

PREFACE: Introduction to the proceedings of Dynamics Days South America 2010

NASA Astrophysics Data System (ADS)

Macau, Elbert E. N.; Pereira, Tiago; Prado, Antonio F. B. A.; Turci, Luiz F. R.; Winter, Othon C.

2011-03-01

This proceedings presents selected contributions from the participants of South America Dynamics Days 2011, which was hosted by the National Institute for Space Research (INPE), Brazil, in July 2010. Dynamics Days was founded in 1980 and is the longest standing and most respected international series of meetings devoted to the field of dynamics and nonlinearity. Traditionally it has brought together researchers from a wide range of backgrounds - including physics, biology, engineering, chemistry and mathematics - for interdisciplinary research into nonlinear science. Dynamics Days South America 2010 marked the beginning of the South American branch of Dynamics Days. It brought together, for the first time in South America, researchers from a wide range of backgrounds who share a common interest in the theory and applications of nonlinear dynamics. Thus, South American researchers had a forum to promote regional as well as international scientific and technological exchange and collaboration especially, but not exclusively, on problems that are particularly relevant for the development of science and technology in the South American region. Furthermore, the conference also brought together prominent scientists from around the world to review recent developments in nonlinear science. This conference comprised plenary invited talks, minisymposia, contributed talks and poster sessions. The articles that are compiled here were chosen from among the works that were presented as contributed talks and posters. They represent a good selection which allows one to put issues that were discussed during the conference into perspective. It is possible to evaluate the success of an initiative by using several indices. In relation to attendees, the conference had 311 participants from 22 countries, who presented 341 works. About 86% of the participants came from South American countries. These figures allow one to classify this Dynamics Days conference as that with the greatest number of attendees ever. Finally, we would like to express our gratitude to all the participants for their presentations, discussions, and remarkable interactions with one another. The tireless work undertaken by all the members of the International Advisory Committee and the Organizing Committee must also be recognized. We also wish to express our deep appreciation for the Scientific Societies and Research Support Agencies which supported the conference and provided all the resources which were necessary to make this idea of a South American Dynamics Days come true. Elbert E N Macau, Tiago Pereira, Antonio F B A Prado, Luiz F R Turci, and Othon C WinterEditors Conference photograph Conference photograph Conference photograph Conference photograph International Advisory Committee Adilson E MotterNorthwestern UniversityEvanston - IL - USA Alfredo OzorioCentro Brasileiro de Pesquisas FísicasRio de Janeiro - RJ - Brazil Celso Grebogi (Chair)University of AberdeenAberdeen - UK Ed OttUniversity of MarylandCollege Park - MD - USA Epaminondas Rosa JrIllinois State UniversityNormal - IL - USA Hans Ingo WeberPontifícia Universidade CatólicaRio de Janeiro - RJ - Brazil Holger KantzMax Planck Institute for the Physics of Complex SystemsDresden - Germany Jason Gallas (Co-chair)Universidade Federal do Rio Grande do SulPorto Alegre - RS - Brazil José Roberto Rios LeiteUniv. Federal de PernanbucoRecife - PE - Brazil Jürgen KurthsPotsdam Institute for climate Impact ResearchHumboldt University, Berlin - Germany Kenneth ShowalterWest Virginia UniversityMorgantown - WV - USA Lou PecoraNaval Research LabWashington - DC - USA Luis Antonio AguirreUniversidade Federal de Minas GeraisBelo Horizonte - MG - Brazil Marcelo VianaIMPA - Instituto Nacional de Matemática Pura e AplicadaRio de Janeiro - RJ - Brazil Miguel A F SanjuánUniversidad Rey Juan CarlosMadrid - Spain Paulo Roberto de Souza MendesPontifícia Universidade CatólicaRio de Janeiro - RJ - Brazil Roland KorbeleUniversidade de São PauloSão Carlos - SP - Brazil Rubens SampaioPontifícia Universidade CatólicaRio de Janeiro - RJ - Brazil Ruedi StoopSwiss Federal Institute of TechnologyUZH/ETHZ Zurich - Switzerland Sylvio Ferraz MelloUniversidade de São PauloSão Paulo - SP - Brazil Takashi YoneyamaITA - Instituto Tecnológico de AeronáuticaSão José dos Campos - SP - Brazil Ying-Cheng LaiArizona State UniversityTempe - AZ - USA Organizing Committee Antonio Carlos Roque da SilvaUSP - Universidade de São PauloRibeirão Preto - SP - Brazil Antonio F Bertachini de Almeida Prado (Co-chair)INPE - Instituto Nacional de Pesquisas EspaciaisSão José dos Campos - SP - Brazil Arturo C MartiFacultad de CienciaMontevideo - Uruguai Carlos Leopoldo Pando LambruschiniBenemérita Universidad Autónoma de PueblaPuebla - Mexico Edson Denis LeonelUNESP - "Júlio de Mesquisa Filho"Rio Claro - SP - Brazil Elbert E N Macau (Chair)INPE - Instituto Nacional de Pesquisas EspaciaisSão José dos Campos - SP - Brazil Gerard Olivar TostUniversidad National de ColombiaManizales - Colombia Hamilton VarelaUSP - Universidade de São PauloSão Carlos - SP - Brazil Hilda Cerdeira (Co-chair)IFT - Instituto de Física TeóricaSão Paulo - SP - Brazil Iberê Luiz CaldasUSP - Universidade de São PauloSão Paulo - SP - Brazil José Manoel BalthazarUNESP - "Júlio de Mesquisa Filho"Rio Claro - SP - Brazil José Roberto Castilho PiqueiraUSP - Universidade de São PauloSão Paulo - SP - Brazil Luciano da Fontoura CostaUSP - Universidade de São PauloSão Carlos - SP - Brazil Luiz de Siqueira Martins FilhoUFABC - Universidade Federal do ABCSanto André - SP - Brazil Marcel G ClercUniversidad de ChileSantiago - Chile Miguel VizcardoUniversidad de ArequipaArequipa - Peru Gonzalo Marcelo Ramirez ÁvilaUniversidad Mayor de San AndrésLa Paz - Bolivia Marco Aurélio Pires IdiartUniversidade Federal do Rio Grande do SulPorto Alegre - RS - Brazil Marcus de AguiarUNICAMPCampinas - SP - Brazil Mario CosenzaUniversidad de Los AndesMerida - Venezuela Othon Cabo WinterUNESP - "Júlio de Mesquisa Filho"Guaratinguetá - SP - Brazil Ricardo Luiz VianaUniversidade Federal do ParanáCuritiba - PA - Brazil Silvina Ponce DawsonUniversidad de Buenos AiresBuenos Aires - Argentina Vivian M GomesINPE - Instituto Nacional de Pesquisas EspaciaisSão José dos Campos - SP - Brazil Realization INPE logo Promotion ABCM logo   SBA logo SBF logo   SBMAC logo Sponsorship CAPES logo   CNPq logo FAPESP logo   ICTP logo Claf logo   SOARD AFOSR logo TAM logo

Entropy and gravity concepts as new methodological indexes to investigate technological convergence: patent network-based approach.

PubMed

Cho, Yongrae; Kim, Minsung

2014-01-01

The volatility and uncertainty in the process of technological developments are growing faster than ever due to rapid technological innovations. Such phenomena result in integration among disparate technology fields. At this point, it is a critical research issue to understand the different roles and the propensity of each element technology for technological convergence. In particular, the network-based approach provides a holistic view in terms of technological linkage structures. Furthermore, the development of new indicators based on network visualization can reveal the dynamic patterns among disparate technologies in the process of technological convergence and provide insights for future technological developments. This research attempts to analyze and discover the patterns of the international patent classification codes of the United States Patent and Trademark Office's patent data in printed electronics, which is a representative technology in the technological convergence process. To this end, we apply the physical idea as a new methodological approach to interpret technological convergence. More specifically, the concepts of entropy and gravity are applied to measure the activities among patent citations and the binding forces among heterogeneous technologies during technological convergence. By applying the entropy and gravity indexes, we could distinguish the characteristic role of each technology in printed electronics. At the technological convergence stage, each technology exhibits idiosyncratic dynamics which tend to decrease technological differences and heterogeneity. Furthermore, through nonlinear regression analysis, we have found the decreasing patterns of disparity over a given total period in the evolution of technological convergence. This research has discovered the specific role of each element technology field and has consequently identified the co-evolutionary patterns of technological convergence. These new findings on the evolutionary patterns of technological convergence provide some implications for engineering and technology foresight research, as well as for corporate strategy and technology policy.

Mediated Effects of Technology Competencies and Experiences on Relations among Attitudes Towards Technology Use, Technology Ownership, and Self Efficacy about Technological Pedagogical Content Knowledge

NASA Astrophysics Data System (ADS)

Yerdelen-Damar, Sevda; Boz, Yezdan; Aydın-Günbatar, Sevgi

2017-08-01

This study examined the relations of preservice science teachers' attitudes towards technology use, technology ownership, technology competencies, and experiences to their self-efficacy beliefs about technological pedagogical content knowledge (TPACK). The present study also investigated interrelations among preservice teachers' attitudes towards technology use, technology ownership, technology competencies, and experiences. The participants of study were 665 elementary preservice science teachers (467 females, 198 males) from 7 colleges in Turkey. The proposed model based on educational technology literature was tested using structural equation modeling. The model testing results revealed that preservice teachers' technology competencies and experiences mediated the relation of technology ownership to their TPACK self efficacy beliefs. The direct relation of their possession of technology to their TPACK self efficacy beliefs was insignificant while the indirect relation through their technology competencies and experiences was significant. The results also indicated there were significant direct effects of preservice teachers' attitudes towards technology use, technology competencies, and experiences on their TPACK self efficacy beliefs.

Technology Transition for Hybrid Warfare

DTIC Science & Technology

2010-02-16

and Iraq. At the same time, the science and technology base must provide the disruptive technologies to defeat future conventional enemies. This... disruptive technologies will be needed to retain long-term technological superiority in conventional warfare. Incremental improvement is the most...technology to be missed. Disruptive technologies are the second type of technological change and involve revolutionary concepts involving large technological

77 FR 13159 - Nanoscale Science, Engineering, and Technology Subcommittee of the Committee on Technology...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-05

... OFFICE OF SCIENCE AND TECHNOLOGY POLICY Nanoscale Science, Engineering, and Technology Subcommittee of the Committee on Technology, National Science and Technology Council Workshop ACTION: Notice of... Nanoscale Science, Engineering, and Technology (NSET) Subcommittee of the Committee on Technology, National...

Power Systems for Future Missions: Appendices A-L

NASA Technical Reports Server (NTRS)

Gill, S. P.; Frye, P. E.; Littman, Franklin D.; Meisl, C. J.

1994-01-01

Selection of power system technology for space applications is typically based on mass, readiness of a particular technology to meet specific mission requirements, and life cycle costs (LCC). The LCC is typically used as a discriminator between competing technologies for a single mission application. All other future applications for a given technology are usually ignored. As a result, development cost of a technology becomes a dominant factor in the LCC comparison. Therefore, it is common for technologies such as DIPS and LMR-CBC to be potentially applicable to a wide range of missions and still lose out in the initial LCC comparison due to high development costs. This collection of appendices (A through L) contains the following power systems technology plans: CBC DIPS Technology Roadmap; PEM PFC Technology Roadmap; NAS Battery Technology Roadmap; PV/RFC Power System Technology Roadmap; PV/NAS Battery Technology Roadmap; Thermionic Reactor Power System Technology Roadmap; SP-100 Power System Technology Roadmap; Dynamic SP-100 Power System Technology Roadmap; Near-Term Solar Dynamic Power System Technology Roadmap; Advanced Solar Dynamic Power System Technology Roadmap; Advanced Stirling Cycle Dynamic Isotope Power System Technology Roadmap; and the ESPPRS (Evolutionary Space Power and Propulsion Requirements System) User's Guide.

New technology for food systems and security.

PubMed

Yau, N J Newton

2009-01-01

In addition to product trade, technology trade has become one of the alternatives for globalization action around the world. Although not all technologies employed on the technology trade platform are innovative technologies, the data base of international technology trade still is a good indicator for observing innovative technologies around world. The technology trade data base from Sinew Consulting Group (SCG) Ltd. was employed as an example to lead the discussion on security or safety issues that may be caused by these innovative technologies. More technologies related to processing, functional ingredients and quality control technology of food were found in the data base of international technology trade platform. The review was conducted by categorizing technologies into the following subcategories in terms of safety and security issues: (1) agricultural materials/ingredients, (2) processing/engineering, (3) additives, (4) packaging/logistics, (5) functional ingredients, (6) miscellaneous (include detection technology). The author discusses examples listed for each subcategory, including GMO technology, nanotechnology, Chinese medicine based functional ingredients, as well as several innovative technologies. Currently, generation of innovative technology advance at a greater pace due to cross-area research and development activities. At the same time, more attention needs to be placed on the employment of these innovative technologies.

75 FR 81678 - Aeronautics Science and Technology Subcommittee; Committee on Technology; National Science and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-28

... OFFICE OF SCIENCE AND TECHNOLOGY POLICY Aeronautics Science and Technology Subcommittee; Committee on Technology; National Science and Technology Council ACTION: Notice of Meeting--Public input is.... SUMMARY: The Aeronautics Science and Technology Subcommittee (ASTS) of the National Science and Technology...

Projecting technology change to improve space technology planning and systems management

NASA Astrophysics Data System (ADS)

Walk, Steven Robert

2011-04-01

Projecting technology performance evolution has been improving over the years. Reliable quantitative forecasting methods have been developed that project the growth, diffusion, and performance of technology in time, including projecting technology substitutions, saturation levels, and performance improvements. These forecasts can be applied at the early stages of space technology planning to better predict available future technology performance, assure the successful selection of technology, and improve technology systems management strategy. Often what is published as a technology forecast is simply scenario planning, usually made by extrapolating current trends into the future, with perhaps some subjective insight added. Typically, the accuracy of such predictions falls rapidly with distance in time. Quantitative technology forecasting (QTF), on the other hand, includes the study of historic data to identify one of or a combination of several recognized universal technology diffusion or substitution patterns. In the same manner that quantitative models of physical phenomena provide excellent predictions of system behavior, so do QTF models provide reliable technological performance trajectories. In practice, a quantitative technology forecast is completed to ascertain with confidence when the projected performance of a technology or system of technologies will occur. Such projections provide reliable time-referenced information when considering cost and performance trade-offs in maintaining, replacing, or migrating a technology, component, or system. This paper introduces various quantitative technology forecasting techniques and illustrates their practical application in space technology and technology systems management.

An investigation into the attitudes of nursing students toward technology.

PubMed

Tubaishat, Ahmad

2014-06-01

Attitudes toward technology may impact the levels of technology acceptance and training willingness among nursing students. Nurse acceptance and effective utilization of technology are critical to improving patient care and safety. The aims of this cross-sectional study were to measurethe attitude of nursing students toward technology and to determine if demographic characteristics affect their attitudinal measures. Furthermore, the amount of formal education provided on the use of technology applications is explored. A convenience sample of nursing students attending a public university in Jordan was recruited, and a technology attitude scale designed to measure the attitude of nursing students toward technology was used. Scales designed to gather data on participant demographics, self-reported technology skills, and level of formal technology education were also used. The results showed that participants held a positive attitude toward technology. Students who reported a high level of technology skill had the most positive attitude toward technology. The impact years of formal education on the use of technology applications were low, whereas academic level had a significant impact on technology attitudes. Senior student participants had the highest level of technology education, likely because of their exposure to relatively more educational opportunities, and the most positive attitude toward technology. Despite the positive attitude of nursing students toward technology, the problem of minimal technology education should be addressed in future nursing programs to further enhance positive attitudes toward technology.

Philosophy of Technology Assumptions in Educational Technology Leadership: Questioning Technological Determinism

ERIC Educational Resources Information Center

Webster, Mark David

2013-01-01

Scholars have emphasized that decisions about technology can be influenced by philosophy of technology assumptions, and have argued for research that critically questions technological determinist assumptions. Empirical studies of technology management in fields other than K-12 education provided evidence that philosophy of technology assumptions,…

Be the Technology: Redefining Technology Integration in Classrooms.

ERIC Educational Resources Information Center

Mills, Steven C.; Tincher, Robert C.

A technology professional development initiative was launched in a school district with the goal of extending technology use in the classroom. For teachers to teach expertly, the aim was for them to "be the technology" by modeling technology use in the classroom, applying technology across the curriculum, applying technology to…

Entropy and Gravity Concepts as New Methodological Indexes to Investigate Technological Convergence: Patent Network-Based Approach

PubMed Central

Cho, Yongrae; Kim, Minsung

2014-01-01

The volatility and uncertainty in the process of technological developments are growing faster than ever due to rapid technological innovations. Such phenomena result in integration among disparate technology fields. At this point, it is a critical research issue to understand the different roles and the propensity of each element technology for technological convergence. In particular, the network-based approach provides a holistic view in terms of technological linkage structures. Furthermore, the development of new indicators based on network visualization can reveal the dynamic patterns among disparate technologies in the process of technological convergence and provide insights for future technological developments. This research attempts to analyze and discover the patterns of the international patent classification codes of the United States Patent and Trademark Office's patent data in printed electronics, which is a representative technology in the technological convergence process. To this end, we apply the physical idea as a new methodological approach to interpret technological convergence. More specifically, the concepts of entropy and gravity are applied to measure the activities among patent citations and the binding forces among heterogeneous technologies during technological convergence. By applying the entropy and gravity indexes, we could distinguish the characteristic role of each technology in printed electronics. At the technological convergence stage, each technology exhibits idiosyncratic dynamics which tend to decrease technological differences and heterogeneity. Furthermore, through nonlinear regression analysis, we have found the decreasing patterns of disparity over a given total period in the evolution of technological convergence. This research has discovered the specific role of each element technology field and has consequently identified the co-evolutionary patterns of technological convergence. These new findings on the evolutionary patterns of technological convergence provide some implications for engineering and technology foresight research, as well as for corporate strategy and technology policy. PMID:24914959

Using bibliographic databases in technology transfer

NASA Technical Reports Server (NTRS)

Huffman, G. David

1987-01-01

When technology developed for a specific purpose is used in another application, the process is called technology transfer--the application of an existing technology to a new use or user for purposes other than those for which the technology was originally intended. Using Bibliographical Databases in Technology Transfer deals with demand-pull transfer, technology transfer that arises from need recognition, and is a guide for conducting demand-pull technology transfer studies. It can be used by a researcher as a self-teaching manual or by an instructor as a classroom text. A major problem of technology transfer is finding applicable technology to transfer. Described in detail is the solution to this problem, the use of computerized, bibliographic databases, which currently contain virtually all documented technology of the past 15 years. A general framework for locating technology is described. NASA technology organizations and private technology transfer firms are listed for consultation.

Mediated Effects of Technology Competencies and Experiences on Relations among Attitudes towards Technology Use, Technology Ownership, and Self Efficacy about Technological Pedagogical Content Knowledge

ERIC Educational Resources Information Center

Yerdelen-Damar, Sevda; Boz, Yezdan; Aydin-Günbatar, Sevgi

2017-01-01

This study examined the relations of preservice science teachers' attitudes towards technology use, technology ownership, technology competencies, and experiences to their self-efficacy beliefs about technological pedagogical content knowledge (TPACK). The present study also investigated interrelations among preservice teachers' attitudes towards…

Adoption and Use of Digital Technologies among General Dental Practitioners in the Netherlands

PubMed Central

van der Zande, Marieke M.; Gorter, Ronald C.; Aartman, Irene H. A.; Wismeijer, Daniel

2015-01-01

Objectives To investigate (1) the degree of digital technology adoption among general dental practitioners, and to assess (2) which personal and practice factors are associated with technology use. Methods A questionnaire was distributed among a stratified sample of 1000 general dental practitioners in the Netherlands, to measure the use of fifteen administrative, communicative, clinical and diagnostic technologies, as well as personal factors and dental practice characteristics. Results The response rate was 31.3%; 65.1% replied to the questionnaire on paper and 34.9% online. Each specific digital technology was used by between 93.2% and 6.8% of the dentists. Administrative technologies were generally used by more dentists than clinical technologies. Dentists had adopted an average number of 6.3±2.3 technologies. 22.5% were low technology users (0 to 4 technologies), 46.2% were intermediate technology users (5 to 7 technologies) and 31.3% were high technology users (8 to12 technologies). High technology users more frequently had a specialization (p<0.001), were younger on average (p=0.024), and worked more hours per week (p=0.003) than low technology users, and invested more hours per year in professional activities (p=0.026) than intermediate technology users. High technology use was also more common for dentists working in practices with a higher average number of patients per year (p<0.001), with more dentists working in the practice (p<0.001) and with more staff (p<0.001). Conclusion With few exceptions, all dentists use some or a substantial number of digital technologies. Technology use is associated with various patterns of person-specific factors, and is higher when working in larger dental practices. The findings provide insight into the current state of digital technology adoption in dental practices. Further exploration why some dentists are more reluctant to adopt technologies than others is valuable for the dental profession’s agility in adjusting to technological developments. PMID:25811594

Science, technology, and pedagogy: Exploring secondary science teachers' effective uses of technology

NASA Astrophysics Data System (ADS)

Guzey, Siddika Selcen

Technology has become a vital part of our professional and personal lives. Today we cannot imagine living without many technological tools such as computers. For the last two decades technology has become inseparable from several areas, such as science. However, it has not been fully integrated into the field of education. The integration of technology in teaching and learning is still challenging even though there has been a historical growth of Internet access and available technology tools in schools (U.S. Department of Education, National Center for Education Statistics, 2006). Most teachers have not incorporated technology into their teaching for various reasons such as lack of knowledge of educational technology tools and having unfavorable beliefs about the effectiveness of technology on student learning. In this study, three beginning science teachers who have achieved successful technology integration were followed to investigate how their beliefs, knowledge, and identity contribute to their uses of technology in their classroom instruction. Extensive classroom observations and interviews were conducted. The findings demonstrate that the participating teachers are all intrinsically motivated to use technology in their teaching and this motivation allows them to enjoy using technology in their instruction and keeps them engaged in technology use. These teachers use a variety of technology tools in their instruction while also allowing students to use them, and they posit a belief set in favor of technology. The major findings of the study are displayed in a model which indicates that teachers' use of technology in classroom instruction was constructed jointly by their technology, pedagogy, and content knowledge; identity; beliefs; and the resources that are available to them and that the internalization of the technology use comes from reflection. The study has implications for teachers, teacher educators, and school administrators for successful technology integration into science classrooms.

The role of technology in critical care nursing.

PubMed

Crocker, Cheryl; Timmons, Stephen

2009-01-01

This paper is a report of a study to identify the meaning for critical care nurses of technology related to weaning from mechanical ventilation and to explore how that technology was used in practice. The literature concerned with the development of critical care (intensive care and high dependency units) focuses mainly on innovative medical technology. Although this use of technology in critical care is portrayed as new, it actually represents a transfer of technology from operating theatres. An ethnographic study was conducted and data were collected on one critical care unit in a large teaching hospital over a 6-month period in 2004. The methods included participant observation, interviews and the collection of field notes. The overall theme 'The nursing-technology relation' was identified. This comprised three sub-themes: definition of technology, technology transferred and technology transformed. Novice nurses took a task-focussed approach to weaning, treating it as a 'medical' technology transferred to them from doctors. Expert nurses used technology differently and saw its potential to become a 'nursing technology'. Nurses need to examine how they can adapt and to 'reconfigure' technology so that it can be transformed into a nursing technology. Those technologies that do not fit with nursing may have no place there. Rather than simply extending and expanding their roles through technology transfer, nurses should transform those technologies that preserve the essence of nursing and can contribute to a positive outcome for patients.

Adopting Digital Technologies in the Classroom: 10 Assessment Questions

ERIC Educational Resources Information Center

Staley, David J.

2004-01-01

Technology has long been a part of the classroom space. Sometime in the 1990s, the word technology was co-opted to refer only to digital tools. "Technology in the classroom" or "technology stocks" or "the dangers posed by technology" came to refer only to digital technology rather than to technology as a whole. As such, much of the discussion…

Technology Estimating: A Process to Determine the Cost and Schedule of Space Technology Research and Development

NASA Technical Reports Server (NTRS)

Cole, Stuart K.; Reeves, John D.; Williams-Byrd, Julie A.; Greenberg, Marc; Comstock, Doug; Olds, John R.; Wallace, Jon; DePasquale, Dominic; Schaffer, Mark

2013-01-01

NASA is investing in new technologies that include 14 primary technology roadmap areas, and aeronautics. Understanding the cost for research and development of these technologies and the time it takes to increase the maturity of the technology is important to the support of the ongoing and future NASA missions. Overall, technology estimating may help provide guidance to technology investment strategies to help improve evaluation of technology affordability, and aid in decision support. The research provides a summary of the framework development of a Technology Estimating process where four technology roadmap areas were selected to be studied. The framework includes definition of terms, discussion for narrowing the focus from 14 NASA Technology Roadmap areas to four, and further refinement to include technologies, TRL range of 2 to 6. Included in this paper is a discussion to address the evaluation of 20 unique technology parameters that were initially identified, evaluated and then subsequently reduced for use in characterizing these technologies. A discussion of data acquisition effort and criteria established for data quality are provided. The findings obtained during the research included gaps identified, and a description of a spreadsheet-based estimating tool initiated as a part of the Technology Estimating process.

Technology Integration Practice as a Function of Pedagogical Expertise.

ERIC Educational Resources Information Center

Pierson, Melissa E.

2001-01-01

Investigated how teachers at various levels of technology use and teaching abilities used technology and how technology use related to general teaching practice. Highlights include teachers' personal definitions of technology integration; planning habits for technology inclusion; strategies for teaching about technology that matched teacher…

75 FR 36722 - Aeronautics Science and Technology Subcommittee; Committee on Technology; National Science and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-28

... OFFICE OF SCIENCE AND TECHNOLOGY POLICY Aeronautics Science and Technology Subcommittee; Committee on Technology; National Science and Technology Council ACTION: Notice of Meeting--Public input is... Evaluation (RDT&E) Infrastructure Plan. SUMMARY: The Aeronautics Science and Technology Subcommittee (ASTS...

77 FR 61448 - Nanoscale Science, Engineering and Technology Subcommittee Committee on Technology, National...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-09

... OFFICE OF SCIENCE AND TECHNOLOGY POLICY Nanoscale Science, Engineering and Technology Subcommittee Committee on Technology, National Science and Technology Council; Public Meetings AGENCY: Executive Office of the President, Office of Science and Technology Policy. ACTION: Notice of Public Meetings. SUMMARY...

Industrial Sector Technology Use Model (ISTUM): industrial energy use in the United States, 1974-2000. Volume 4. Technology appendix. Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1979-10-01

Volume IV of the ISTUM documentation gives information on the individual technology specifications, but relates closely with Chapter II of Volume I. The emphasis in that chapter is on providing an overview of where each technology fits into the general-model logic. Volume IV presents the actual cost structure and specification of every technology modeled in ISTUM. The first chapter presents a general overview of the ISTUM technology data base. It includes an explanation of the data base printouts and how the separate-cost building blocks are combined to derive an aggregate-technology cost. The remaining chapters are devoted to documenting the specific-technologymore » cost specifications. Technologies included are: conventional technologies (boiler and non-boiler conventional technologies); fossil-energy technologies (atmospheric fluidized bed combustion, low Btu coal and medium Btu coal gasification); cogeneration (steam, machine drive, and electrolytic service sectors); and solar and geothermal technologies (solar steam, solar space heat, and geothermal steam technologies), and conservation technologies.« less

Technology transfer methodology

NASA Technical Reports Server (NTRS)

Labotz, Rich

1991-01-01

Information on technology transfer methodology is given in viewgraph form. Topics covered include problems in economics, technology drivers, inhibitors to using improved technology in development, technology application opportunities, and co-sponsorship of technology.

Ares Project Technology Assessment: Approach and Tools

NASA Technical Reports Server (NTRS)

Hueter, Uwe; Tyson, Richard

2010-01-01

Technology assessments provide a status of the development maturity of specific technologies. Along with benefit analysis, the risks the project assumes can be quantified. Normally due to budget constraints, the competing technologies are prioritized and decisions are made which ones to fund. A detailed technology development plan is produced for the selected technologies to provide a roadmap to reach the desired maturity by the project s critical design review. Technology assessments can be conducted for both technology only tasks or for product development programs. This paper is primarily biased toward the product development programs. The paper discusses the Ares Project s approach to technology assessment. System benefit analysis, risk assessment, technology prioritization, and technology readiness assessment are addressed. A description of the technology readiness level tool being used is provided.

(Ir)reconcilable differences? The debate concerning nursing and technology.

PubMed

Sandelowski, M

1997-01-01

To review and critique the debate concerning nursing and technology. Technology has been considered both at one and at odds with nursing. Mitcham's (1994) concepts of technological optimism and romanticism. Nursing literature since 1960. Historical analysis. Technological optimists in nursing have viewed technology as an extension of and as readily assimilable into humanistic nursing practice, and nursing as socially advantaged by technology. Technological romantics have viewed technology as irreconcilable with nursing culture, as an expression of masculine culture, and as recirculating existing gender and social inequalities. Both optimists and romantics essentialize technology and nursing, treating the two as singular and fixed entities. The (ir)reconcilability of nursing and technology may be a function of how devices are used by people in different contexts, or of the (ir)reconcilability of views of technology in nursing.

76 FR 76388 - National Medal of Technology and Innovation Nomination Application

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-07

... Medal of Technology and Innovation is the highest honor for technological achievement bestowed by the... commercialization of technology products, processes and concepts, technological innovation, and development of the Nation's technological manpower. The purpose of the National Medal of Technology and Innovation is to...

78 FR 24241 - Nanoscale Science, Engineering, and Technology Subcommittee; Committee on Technology, National...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-24

... OFFICE OF SCIENCE AND TECHNOLOGY POLICY Nanoscale Science, Engineering, and Technology Subcommittee; Committee on Technology, National Science and Technology Council; Notice of Public Meeting AGENCY: Executive Office of the President, Office of Science and Technology Policy. ACTION: Notice of Public Meeting...

PREFACE: Turbulent Mixing and Beyond Turbulent Mixing and Beyond

NASA Astrophysics Data System (ADS)

Abarzhi, Snezhana I.; Gauthier, Serge; Rosner, Robert

2008-10-01

The goals of the International Conference `Turbulent Mixing and Beyond' are to expose the generic problem of Turbulence and Turbulent Mixing in Unsteady Flows to a wide scientific community, to promote the development of new ideas in tackling the fundamental aspects of the problem, to assist in the application of novel approaches in a broad range of phenomena, where the non-canonical turbulent processes occur, and to have a potential impact on technology. The Conference provides the opportunity to bring together scientists from the areas which include, but are not limited to, high energy density physics, plasmas, fluid dynamics, turbulence, combustion, material science, geophysics, astrophysics, optics and telecommunications, applied mathematics, probability and statistics, and to have their attention focused on the long-standing formidable task. The Turbulent Mixing and Turbulence in Unsteady Flows, including multiphase flows, plays a key role in a wide variety of phenomena, ranging from astrophysical to nano-scales, under either high or low energy density conditions. Inertial confinement and magnetic fusion, light-matter interaction and non-equilibrium heat transfer, properties of materials under high strain rates, strong shocks, explosions, blast waves, supernovae and accretion disks, stellar non-Boussinesq and magneto-convection, planetary interiors and mantle-lithosphere tectonics, premixed and non-premixed combustion, oceanography, atmospheric flows, unsteady boundary layers, hypersonic and supersonic flows, are a few examples to list. A grip on unsteady turbulent processes is crucial for cutting-edge technology such as laser-micromachining and free-space optical telecommunications, and for industrial applications in aeronautics. Unsteady Turbulent Processes are anisotropic, non-local and multi-scale, and their fundamental scaling, spectral and invariant properties depart from the classical Kolmogorov scenario. The singular aspects and similarity of the mixing dynamics are interplayed with fundamental properties of the Euler and compressible Navier-Stokes equations, with the problem sensitivity to the initial conditions and to the boundary conditions at the discontinuities, and with its stochastic description. The state-of-the-art numerical simulations of the multi-phase non-equilibrium dynamics suggest new methods for capturing discontinuities and singularities and shock-interface interaction, for predictive modeling of the multi-scale dynamics in fluids and plasmas, for error estimate and uncertainty quantification as well as for novel data assimilation techniques. The First International Conference `Turbulent Mixing and Beyond' (TMB-2007), was held on 18-26 August 2007 at the Abdus Salam International Centre for Theoretical Physics, Trieste, Italy. This was a highly informative and exciting meeting, by all the standards a major success. The Conference brought together 120 participants (307 authors) from five continents, ranging from students to members of National Academies of Sciences and Engineering and including researchers from the Universities, National Laboratories, Leading Scientific Institutions and Industry. TMB-2007 covered 16 different topics, maintaining the scope and the interdisciplinary character of the meeting, and kept the focus on a fundamental fluid dynamic problem of unsteady turbulent processes and the Conference Objectives. The success of the TMB-07 was a result of the successful work of all the participants, who were serious and professional people, caring for the quality of their research and sharing their scientific vision. The level of presentations was high, and the presentations included 87 oral contributions, 32 invited lectures and 5 tutorials and over 30 poster contributions. The round table discussions held at TMB-2007 investigated the organization of a Collaborative Computing Environment for the Turbulent Mixing and Beyond Community. The abstracts of the 150 accepted Conference presentations were published in the Book of Abstracts, International Conference `Turbulent Mixing and Beyond', August 18-26, 2007, Copyright 2007 Abdus Salam International Centre for Theoretical Physics, Trieste, Italy, ISBN 92-95003-36-5. This Topical Issue consists of nearly 60 articles accepted for publication in the Conference Proceedings and reflects a substantial part of the Conference contributions. The articles cover a broad variety of TMB-2007 themes and are sorted alphabetically by the last name of the first author within each of the following topics: Canonical Turbulence and Turbulent Mixing (invariant, scaling, spectral properties, scalar transports) Wall-bounded Flows (structure and fundamentals, unsteady boundary layers, super-sonic flows, shock - boundary layer interaction) Interfacial Dynamics (Rayleigh-Taylor, Richtmyer-Meshkov and Kelvin-Helmholtz instabilities) Unsteady Turbulent Processes (turbulence and turbulent mixing in unsteady, multiphase and anisotropic flows) High Energy Density Physics (laser-material interaction, Z-pinches, laser-driven, heavy-ion and magnetic fusion) Astrophysics (supernovae, interstellar medium, star formation, stellar interiors, early Universe, cosmic micro-wave background) Magneto-hydrodynamics (magneto-convection, magneto-rotational instability, accretion disks, dynamo) Plasmas in Ionosphere (coupled plasmas, anomalous resistance, ionosphere) Physics of Atmosphere (environmental fluid dynamics, forecasting, data analysis, error estimate) Geophysics (turbulent convection in stratified, rotating and active flows) Combustion (dynamics of flames, fires, blast waves and explosions) Mathematical Aspects of Multi-Scale Dynamics (vortex dynamics, singularities, discontinuities, asymptotic dynamics, weak solutions, well- and ill-posedness) Statistical Approaches, Stochastic Processes and Probabilistic Description (uncertainty quantification, anomalous diffusion, long-tail distributions, wavelets) Advanced Numerical Simulations (continuous DNS/LES/RANS, Molecular dynamics, Monte-Carlo, predictive modeling) New Experimental Diagnostics (novel methods for flow visualization and control, high-tech) The First International Conference `Turbulent Mixing and Beyond' was organized by the following members of the Organizing Committee: Snezhana I Abarzhi (chairperson, Chicago, USA) Malcolm J Andrews (Los Alamos National Laboratory, USA) Sergei I Anisimov (Landau Institute for Theoretical Physics, Russia) Serge Gauthier (Commissariat à l'Energie Atomique, France) Donald Q Lamb (The University of Chicago, USA) Katsunobu Nishihara (Institute for Laser Engineering, Osaka, Japan) Bruce A Remington (Lawrence Livermore National Laboratory, USA) Robert Rosner (Argonne National Laboratory, USA) Katepalli R Sreenivasan (International Centre for Theoretical Physics, Italy) Alexander L Velikovich (Naval Research Laboratory, USA) The Organizing Committee gratefully acknowledges the financial support of the Conference Sponsors: National Science Foundation (NSF), USA (Divisions and Programs Directors: Drs A G Detwiler, L M Jameson, E L Lomon, P E Phelan, G A Prentice, J A Raper, W Schultz, P R Westmoreland; PI: Dr S I Abarzhi) Air Force Office of Scientific Research (AFOSR), USA (Program Director: Dr J D Schmisseur; PI: Dr S I Abarzhi) European Office of Aerospace Research and Development (EOARD) of the AFOSR, UK (Program Chief: Dr S Surampudi; PI: Dr S I Abarzhi) International Centre for Theoretical Physics (ICTP), Trieste, Italy (Centre's Director: Dr K R Sreenivasan) The University of Chicago and The Argonne National Laboratory (ANL), USA (Laboratory's Director: Dr R Rosner) Commissariat à l'Energie Atomique (CEA), France (Directeur de Recherche: Dr S Gauthier) Department of Energy, Los Alamos National Laboratory (LANL), USA (Program manager: Dr R J Hanrahan; Group Leader: Dr M J Andrew) The DOE ASC Alliance Center for Astrophysical Thermonuclear Flashes, The University of Chicago, USA (Center's Director: Dr D Q Lamb) Institute for Laser Engineering (ILE), Osaka, Japan (Division Head: Dr K Nishihara) Illinois Institute of Technology (IIT), Chicago, USA (College of Science and Letters, Department of Applied Mathematics: Dr S I Abarji) and thanks them for making this event possible. The Organizing Committee appreciates the assistance of Suzie Radosic (administrator and assistant, ICTP) Daniil Ilyin (web-master, Chicago) Elena Magnus (assistant, Chicago) We express our gratitude for the help with the Conference Program to the members of the Scientific Advisory Committee S I Abarzhi (The University of Chicago, Illinois Institute of Technology, USA) G Ahlers (University of California at Santa Barbara, USA) M J Andrews (Los Alamos National Laboratory, Texas A & M University, USA) S I Anisimov (Landau Institute for Theoretical Physics, Russia) E Bodenschatz (Max Plank Institute, Gottingen, Germany) S Dalziel (DAMTP, University of Cambridge, UK) R Ecke (Los Alamos National Laboratory, USA) H J Fernando (Arizona State University, USA) S Gauthier (Commissariat à l'Energie Atomique, France) G A Glatzmaier (University of California at Santa Cruz, USA) W A Goddard III (California Institute of Technology, USA) L P Kadanoff (The University of Chicago, USA) D Q Lamb (The University of Chicago, USA) D P Lathrop (University of Maryland, USA) S Lebedev (Imperial College, UK) P Manneville (Ecole Polytechnique, France) D I Meiron (California Institute of Technology, USA) H Nagib (Illinois Institute of Technology, Chicago, USA) J Niemela (International Center for Theoretical Physics, Italy) K Nishihara (Institute for Laser Engineering, Osaka, Japan) S A Orszag (Yale University, USA) E Ott (University of Maryland, USA) N Peters (RWTS, Aachen, Germany) S B Pope (Cornell, USA) B A Remington (Lawrence Livermore National Laboratory, USA) R Rosner (Argonne National Laboratory and The University of Chicago, USA) A Schmidt (Naval Research Laboratory, USA) K R Sreenivasan (International Centre for Theoretical Physics, Italy) V Steinberg (Weiznmann Institute, Israel) A L Velikovich (Naval Research Laboratory, USA) P K Yeung (Georgia Institute of Technology, USA) F A Williams (University of California at San Diego, USA) We would like to thank all the authors and the referees for their contributions to this Topical Issue and for offering their expertise, time and effort We cordially invite the reader to take a look at this Topical Issue for information on the frontiers of theoretical, numerical and experimental research and technology The Organizing Committee hopes the TMB Conference will serve to advance the state-of-the-art in understanding of fundamental physical properties of turbulent mixing and turbulence in unsteady flows and will have an impact on predictive modeling capabilities, physical description and, ultimately, control of these complex processes Snezhana I Abarzhi, Serge Gauthier, Robert Rosner Chicago, 20 Nov 2008

Technology 2000, volume 2

NASA Technical Reports Server (NTRS)

1991-01-01

Technology 2000 was the first major industrial conference and exposition spotlighting NASA technology and technology transfer. It's purpose was, and continues to be, to increase awareness of existing NASA-developed technologies that are available for immediate use in the development of new products and processes, and to lay the groundwork for the effective utilization of emerging technologies. Included are sessions on: computer technology and software engineering; human factors engineering and life sciences; materials science; sensors and measurement technology; artificial intelligence; environmental technology; optics and communications; and superconductivity.

Center for development technology and program in technology and human affairs. [emphasizing technology-based networks

NASA Technical Reports Server (NTRS)

Wong, M. D.

1974-01-01

The role of technology in nontraditional higher education with particular emphasis on technology-based networks is analyzed nontraditional programs, institutions, and consortia are briefly reviewed. Nontraditional programs which utilize technology are studied. Technology-based networks are surveyed and analyzed with regard to kinds of students, learning locations, technology utilization, interinstitutional relationships, cost aspects, problems, and future outlook.

Initiating the 2002 Mars Science Laboratory (MSL) Focused Technology Program

NASA Technical Reports Server (NTRS)

Caffrey, Robert T.; Udomkesmalee, Gabriel; Hayati, Samad A.

2004-01-01

The Mars Science Laboratory (MSL) Project is an aggressive mission launching in 2009 to deliver a new generation of rover safely to the surface of Mars and conduct comprehensive in situ investigations using a new generation of instruments. This system will be designed to land with precision and be capable of operating over a large percentage on the surface of Mars. It will have capabilities that will support NASA's scientific goals into the next decade of exphation. The MSL Technology program is developing a wide-range of technologies needed for this Mission and potentially other space missions. The MSL Technology Program reports to both the MSL Project and the Mars Technology Program (MTP). The dual reporting process creates a challenging management situation, but ensures the new technology meets both the specific MSL requirements and the broader Mars Program requirements. MTP is a NASA-wide technology development program managed by the Jet Propulsion Laboratory (JPL) and is divided into a Focused Program and a Base Program. The Focused Technology Program addresses technologies that are specific and critical to near-term missions, while the Base Technology Program addresses those technologies that are applicable to multiple missions and which can be characterized as longer term, higher risk, and high payoff technologies. The MSL Technology Program is under the Focused Program and is tightly coupled to MSL's mission milestones and deliverables. The technology budget is separate from the flight Project budget, but the technology s requirements and the development process are tightly coordinated with the Project. The Technology Program combines proven management techniques of flight projects with commercial and academic technology management strategies, to create a technology management program that meets the near-term requirements of MSL and the long-term requirements of MTP. This paper examines the initiation of 2002 MSL Technology program. Some of the areas discussed in this paper include technology definition, task selection, technology management, and technology assessment.

Technology transfer within the NASA Goddard Space Flight Center

NASA Technical Reports Server (NTRS)

Plotkin, Henry H.

1992-01-01

Viewgraphs on technology transfer within the NASA Goddard Space Flight Center presented to Civil Space Technology Development workshop on technology transfer and effectiveness are provided. Topics covered include: obstacles to technology transfer; technology transfer improvement program at GSFC: communication between technology developers and users; and user feedback to technologists.

Space Transportation Technology Workshop: Propulsion Research and Technology

NASA Technical Reports Server (NTRS)

2000-01-01

This viewgraph presentation gives an overview of the Space Transportation Technology Workshop topics, including Propulsion Research and Technology (PR&T) project level organization, FY 2001 - 2006 project roadmap, points of contact, foundation technologies, auxiliary propulsion technology, PR&T Low Cost Turbo Rocket, and PR&T advanced reusable technologies RBCC test bed.

Technological Literacy Education and Technological and Vocational Education in Taiwan

ERIC Educational Resources Information Center

Lee, Lung-Sheng Steven

2010-01-01

Technology education in Taiwan is categorized into the following two types: (1) technological literacy education (TLE)--the education for all people to become technological literates; and (2) technological specialty education (TSE)--the education for specific people to become technicians and professionals for technology-related jobs. This paper…

Initiating the 2002 Mars Science Laboratory (MSL) Technology Program

NASA Technical Reports Server (NTRS)

Caffrey, Robert T.; Udomkesmalee, Gabriel; Hayati, Samad A.; Henderson, Rebecca

2004-01-01

The Mars Science Laboratory (MSL) Project is an aggressive mission launching in 2009 to investigate the Martian environment and requires new capabilities that are currently are not available. The MSL Technology Program is developing a wide-range of technologies needed for this Mission and potentially other space missions. The MSL Technology Program reports to both the MSL Project and the Mars Technology Program (MTP). The dual reporting process creates a challenging management situation, but ensures the new technology meets both the specific MSL requirements and the broader Mars Program requirements. MTP is a NASA-wide technology development program managed by JPL and is divided into a Focused Program and a Base Program. The MSL Technology Program is under the focused program and is tightly coupled to MSL's mission milestones and deliverables. The technology budget is separate from the flight Project budget, but the technology's requirements and the development process are tightly coordinated with the Project. The MSL Technology Program combines the proven management techniques of flight projects with the commercial technology management strategies of industry and academia, to create a technology management program that meets the short-term requirements of MSL and the long-term requirements of MTP. This paper examines the initiation of 2002 MSL Technology program. Some of the areas discussed in this paper include technology definition, task selection, technology management, and technology assessment. This paper also provides an update of the 2003 MSL technology program and examines some of the drivers that changed the program from its initiation.

Annual Science and Engineering Technology Conference/DOD Technology Exposition (7th). Volume 2. Wednesday - Thursday

DTIC Science & Technology

2006-04-20

Disruptive Technologies • Army Approach to Disruptive Technologies and Transition Mr. Dennis Schmidt, Director, Science & Technology Integration, Office of...the Assistant Secretary of the Army for Research and Technology • Navy Approach to Disruptive Technologies and Transition Mr. Lewis DeSandre, Program...Manager, ONR 351 • Air Force Approach to Disruptive Technologies and Transition Colonel Mark Stephen, Associate Deputy Assistant Secretary (Science

7th Annual Science and Engineering Technology Conference/DoD Technology Exposition Volume 1

DTIC Science & Technology

2006-04-20

Disruptive Technologies • Army Approach to Disruptive Technologies and Transition Mr. Dennis Schmidt, Director, Science & Technology Integration, Office of...the Assistant Secretary of the Army for Research and Technology • Navy Approach to Disruptive Technologies and Transition Mr. Lewis DeSandre, Program...Manager, ONR 351 • Air Force Approach to Disruptive Technologies and Transition Colonel Mark Stephen, Associate Deputy Assistant Secretary (Science

Introducing Current Technologies

NASA Technical Reports Server (NTRS)

Mitchell, Tiffany

1995-01-01

The objective of the study was a continuation of the 'technology push' activities that the Technology Transfer Team conducts at this time. It was my responsibility to research current technologies at Langley Research Center and find a commercial market for these technologies in the private industry. After locating a market for the technologies, a mailing package was put together which informed the companies of the benefits of NASA Langley's technologies. The mailing package included articles written about the technology, patent material, abstracts from technical papers, and one-pagers which were used at the Technology Opportunities Showcase (TOPS) exhibitions. The companies were encouraged to consult key team members for further information on the technologies.

Prioritizing Information Technology Investments: Assessing the Correlations among Technological Readiness, Information Technology Flexibility, and Information Technology Effectiveness

ERIC Educational Resources Information Center

Walter, John T.

2010-01-01

Management's dilemma, when allocating financial resources towards the improvement of technological readiness and IT flexibility within their organizations, is to control financial risk and maximize IT effectiveness. Technological readiness is people's propensity to embrace and use technology. Its drivers are optimism, innovativeness, discomfort,…

The Impact of In-Service Technology Training Programmes on Technology Teachers

ERIC Educational Resources Information Center

Gumbo, Mishack; Makgato, Moses; Muller, Helene

2012-01-01

The aim of this paper is to assess the impact the Advanced Certificate in Education (ACE) in-service technology training program has on technology teachers' knowledge and understanding of technology. The training of technology teachers is an initiative toward teachers' professional development within the mathematics, science, and technology sphere…

Gender and Technology in Hong Kong: A Study of Pupils' Attitudes toward Technology.

ERIC Educational Resources Information Center

Volk, Kenneth S.; Ming, Yip Wai

1999-01-01

Discussion of attitudes toward traditional male and female roles and technology focuses on a study of Hong Kong secondary school students that used a Pupils' Attitudes toward Technology (PATT) instrument to investigate perceptions of the difficulty of technology, technology in the curriculum, pursuing technology careers, parents' careers, home…

The Complete Picture: "Standards for Technological Literacy" and "Advancing Excellence in Technological Literacy."

ERIC Educational Resources Information Center

Technology Teacher, 2003

2003-01-01

Provides an overview of the "Standards for Technological Literacy: Content for the Study of Technology" (STL) and "Advancing Excellence in Technological Literacy: Student Assessment, Professional Development, and Program Standards" (AETL). Shows how the documents work together to advance the technological literacy of technology educators and K-12…

Technology Estimating 2: A Process to Determine the Cost and Schedule of Space Technology Research and Development

NASA Technical Reports Server (NTRS)

Cole, Stuart K.; Wallace, Jon; Schaffer, Mark; May, M. Scott; Greenberg, Marc W.

2014-01-01

As a leader in space technology research and development, NASA is continuing in the development of the Technology Estimating process, initiated in 2012, for estimating the cost and schedule of low maturity technology research and development, where the Technology Readiness Level is less than TRL 6. NASA' s Technology Roadmap areas consist of 14 technology areas. The focus of this continuing Technology Estimating effort included four Technology Areas (TA): TA3 Space Power and Energy Storage, TA4 Robotics, TA8 Instruments, and TA12 Materials, to confine the research to the most abundant data pool. This research report continues the development of technology estimating efforts completed during 2013-2014, and addresses the refinement of parameters selected and recommended for use in the estimating process, where the parameters developed are applicable to Cost Estimating Relationships (CERs) used in the parametric cost estimating analysis. This research addresses the architecture for administration of the Technology Cost and Scheduling Estimating tool, the parameters suggested for computer software adjunct to any technology area, and the identification of gaps in the Technology Estimating process.

The influence of technology in nursing education.

PubMed

Krau, Stephen D

2015-06-01

The complexity of the relationship between nursing and technology is not new. The complexity has increased with the advent of new technology and technological devices. For faculty who are in the clinical area on a limited basis, and for nurses who are not involved in decisions related to the adoption of technology, terms and concepts related to technology can be misconstrued or misunderstood. An overview of some major terms used in reference to technology and technological approaches can only enhance the intricate relationship between nursing and technology. Copyright © 2015 Elsevier Inc. All rights reserved.

Physics of the Cosmos Program Annual Technology Report

NASA Technical Reports Server (NTRS)

Pham, Bruce Thai; Cardiff, Ann H.

2015-01-01

What's in this Report? What's New? This fifth Program Annual Technology Report (PATR) summarizes the Programs technology development activities for fiscal year (FY) 2015. The PATR serves four purposes.1. Summarize the technology gaps identified by the astrophysics community;2. Present the results of this years technology gap prioritization by the PCOS Technology Management Board (TMB);3. Report on newly funded PCOS Strategic Astrophysics Technology (SAT) projects; and4. Detail progress, current status, and activities planned for the coming year for all technologies supported by PCOS Supporting Research and Technology (SRT) funding in FY 2015. .

Developing an instrument for assessing students' concepts of the nature of technology

NASA Astrophysics Data System (ADS)

Liou, Pey-Yan

2015-05-01

Background:The nature of technology has been rarely discussed despite the fact that technology plays an essential role in modern society. It is important to discuss students' concepts of the nature of technology, and further to advance their technological literacy and adaptation to modern society. There is a need to assess high school students' concepts of the nature of technology. Purpose:This study aims to engage in discourse on students' concepts of the nature of technology based on a proposed theoretical framework. Moreover, another goal is to develop an instrument for measuring students' concepts of the nature of technology. Sample:Four hundred and fifty-five high school students' perceptions of technology were qualitatively analyzed. Furthermore, 530 students' responses to a newly developed questionnaire were quantitatively analyzed in the final test. Design and method:First, content analysis was utilized to discuss and categorize students' statements regarding technology and its related issues. The Student Concepts of the Nature of Technology Questionnaire was developed based on the proposed theoretical framework and was supported by the students' qualitative data. Finally, exploratory factor analysis and reliability analysis were applied to determine the structure of the items and the internal consistency of each scale. Results:Through a process of instrument development, the Student Concepts of the Nature of Technology Questionnaire was shown to be a valid and reliable tool for measuring students' concepts of the nature of technology. This newly developed questionnaire is composed of 29 items in six scales, namely 'technology as artifacts,' 'technology as an innovation change,' 'the current role of technology in society,' 'technology as a double-edged sword,' 'technology as a science-based form,' and 'history of technology.' Conclusions:The Student Concepts of the Nature of Technology Questionnaire has been confirmed as a reasonably valid and reliable instrument. This study provides a useful questionnaire for educational researchers and practitioners for measuring students' concepts of the nature of technology.

DEVELOPMENT OF EMERGING TECHNOLOGIES WITHIN THE SITE PROGRAM

EPA Science Inventory

The Site Program is formed by five research programs: the Demonstration Program, the Emerging Technology Program, the Measurement and Monitoring Technology Development Program, the Innovative Technology Program, and the Technology Transfer Program. The Emerging Technology (ET) P...

SUPERFUND INNOVATIVE TECHNOLOGY EVALUATION - TECHNOLOGY PROFILES

EPA Science Inventory

This document is intended as a reference guide for EPA Regional decision makers and others interested in technologies in the SITE Demonstration and Emerging Technologies programs. The Technologies are described in technology profiles, presented in alphabetical order by developer ...

Earth Science Geostationary Platform Technology

NASA Technical Reports Server (NTRS)

Wright, Robert L. (Editor); Campbell, Thomas G. (Editor)

1989-01-01

The objective of the workshop was to address problems in science and in four technology areas (large space antenna technology, microwave sensor technology, electromagnetics-phased array adaptive systems technology, and optical metrology technology) related to Earth Science Geostationary Platform missions.

Site Remediation Technology InfoBase: A Guide to Federal Programs, Information Resources, and Publications on Contaminated Site Cleanup Technologies. First Edition

NASA Technical Reports Server (NTRS)

1998-01-01

Table of Contents: Federal Cleanup Programs; Federal Site Remediation Technology Development Assistance Programs; Federal Site Remediation Technology Development Electronic Data Bases; Federal Electronic Resources for Site Remediation Technology Information; Other Electronic Resources for Site Remediation Technology Information; Other Electronic Resources for Site Remediation Technology Information; Selected Bibliography: Federal Publication on Alternative and Innovative Site Remediation; and Appendix: Technology Program Contacts.

User needs as a basis for advanced technology. [U.S. civil space program

NASA Technical Reports Server (NTRS)

Mankins, John C.; Reck, Gregory M.

1992-01-01

The NASA Integrated Technology Plan (ITP) is described with treatment given to the identification of U.S. technology needs, space research and technology programs, and some ITP implementations. The ITP is based on the development and transfer of technologies relevant to the space program that also have significant implications for general technological research. Among the areas of technological research identified are: astrophysics, earth sciences, microgravity, and space physics. The Office of Space Science and Applications prioritizes the technology needs in three classes; the highest priority is given to submm and microwave technologies for earth sciences and astrophysics study. Other government and commercial needs are outlined that include cryogenic technologies, low-cost engines, advanced data/signal processing, and low-cost ELVs. It is demonstrated that by identifying and addressing these areas of user technology needs NASA's research and technology program can enhance U.S. trade and industrial competitiveness.

NASA/ESTO investments in remote sensing technologies (Conference Presentation)

NASA Astrophysics Data System (ADS)

Babu, Sachidananda R.

2017-02-01

For more then 18 years NASA Earth Science Technology Office has been investing in remote sensing technologies. During this period ESTO has invested in more then 900 tasks. These tasks are managed under multiple programs like Instrument Incubator Program (IIP), Advanced Component Technology (ACT), Advanced Information Systems Technology (AIST), In-Space Validation of Earth Science Technologies (InVEST), Sustainable Land Imaging - Technology (SLI-T) and others. This covers the whole spectrum of technologies from component to full up satellite in space and software. Over the years many of these technologies have been infused into space missions like Aquarius, SMAP, CYGNSS, SWOT, TEMPO and others. Over the years ESTO is actively investing in Infrared sensor technologies for space applications. Recent investments have been for SLI-T and InVEST program. On these tasks technology development is from simple Bolometers to Advanced Photonic waveguide based spectrometers. Some of the details on these missions and technologies will be presented.

ESTO Investments in Innovative Sensor Technologies for Remote Sensing

NASA Technical Reports Server (NTRS)

Babu, Sachidananda R.

2017-01-01

For more then 18 years NASA Earth Science Technology Office has been investing in remote sensing technologies. During this period ESTO has invested in more then 900 tasks. These tasks are managed under multiple programs like Instrument Incubator Program (IIP), Advanced Component Technology (ACT), Advanced Information Systems Technology (AIST), In-Space Validation of Earth Science Technologies (InVEST), Sustainable Land Imaging - Technology (SLI-T) and others. This covers the whole spectrum of technologies from component to full up satellite in space and software. Over the years many of these technologies have been infused into space missions like Aquarius, SMAP, CYGNSS, SWOT, TEMPO and others. Over the years ESTO is actively investing in Infrared sensor technologies for space applications. Recent investments have been for SLI-T and InVEST program. On these tasks technology development is from simple Bolometers to Advanced Photonic waveguide based spectrometers. Some of the details on these missions and technologies will be presented.

Technology and its ethics in nursing and caring journals: An integrative literature review.

PubMed

Korhonen, Eila-Sisko; Nordman, Tina; Eriksson, Katie

2015-08-01

Over the past 20 years, the impact of technology has increased significantly in health care. The diversity of technology is growing and its knowledge scattered. The concept of technology is ambiguous in caring and nursing sciences and its ethics remains unidentified. To find evidence on how the concept of technology and its ethics are defined in caring and nursing sciences and practice. The purpose of this study is to describe and summarize the concept of technology and its ethics in the past nursing and caring literature. The integrative literature review of the past nursing and caring literature. The data were collected from caring and nursing journal articles from 2000 to 2013 focusing on technology and its ethics.The results were summarized and themed. Technology as a concept has three implications. First, technology is devices and products, including ICT and advanced, simple and assistive technology. Second, technology refers to a process consisting of methods for helping people. Third, technology as a service indicates the production of care by technology. The ethics of technology has not been established as a guiding principle. Some studies excluded ethical reflection completely. Many studies discussed the ethics of technology as benefits such as improved communication and symptoms management, and the simple use of e-health services whilst others remained critical presenting ethical problems such as unwillingness and the inability to use technology, or conflicts with human aspects or questions of inequality. In conclusion, this study indicates that technology as a concept is described diversely. The relation between technology and ethics is not a truism. Despite some evidence, more is needed to promote ethical care when using technology. © The Author(s) 2014.

Smart and intelligent sensor payload project

NASA Image and Video Library

2009-04-01

Engineers working on the smart and intelligent sensor payload project include (l to r): Ed Conley (NASA), Mark Mitchell (Jacobs Technology), Luke Richards (NASA), Robert Drackett (Jacobs Technology), Mark Turowski (Jacobs Technology) , Richard Franzl (seated, Jacobs Technology), Greg McVay (Jacobs Technology), Brianne Guillot (Jacobs Technology), Jon Morris (Jacobs Technology), Stephen Rawls (NASA), John Schmalzel (NASA) and Andrew Bracey (NASA).

Metrology for Information Technology

DTIC Science & Technology

1997-05-01

Technology (IT) MEL/ITL Task Group on Metrology for Information Technology (IT) U.S. DEPARTMENT OF COMMERCE Technology Administration National Institute of...NIST management requested a white paper on metrology for information technology (IT). A task group was formed to develop this white paper with...representatives from the Manufacturing Engineering Laboratory (MEL), the Information Technology Laboratory (ITL), and Technology Services (TS). The task

Growing Misconception of Technology: Investigation of Elementary Students' Recognition of and Reasoning about Technological Artifacts

ERIC Educational Resources Information Center

Firat, Mehmet

2017-01-01

Knowledge of technology is an educational goal of science education. A primary way of increasing technology literacy in a society is to develop students' conception of technology starting from their elementary school years. However, there is a lack of research on student recognition of and reasoning about technology and technological artifacts. In…

Targeting at the Speed of Light

DTIC Science & Technology

2007-02-23

Christensen states: “it is the combination of new disruptive technologies which could have significant impact on nations such as the United States.”6...technology? According to Harvard Professor, Clayton Christensen, there are two technologies: sustaining technologies and disruptive technologies . Sustaining...problems dealing with disruptive technologies . Disruptive technologies are generally "cheaper, simpler, smaller, and, frequently, more convenient

Active and Passive Technology Integration: A Novel Approach for Managing Technology's Influence on Learning Experiences in Context-Aware Learning Spaces

ERIC Educational Resources Information Center

Laine, Teemu H.; Nygren, Eeva

2016-01-01

Technology integration is the process of overcoming different barriers that hinder efficient utilisation of learning technologies. The authors divide technology integration into two components based on technology's role in the integration process. In active integration, the technology integrates learning resources into a learning space, making it…

"Obligatory Technologies": Explaining Why People Feel Compelled to Use Certain Technologies

ERIC Educational Resources Information Center

Chandler, Jennifer A.

2012-01-01

The ideas of technological determinism and the autonomy of technology are long-standing and widespread. This article explores why the use of certain technologies is perceived to be obligatory, thus fueling the fatalism of technological determinism and undermining our sense of freedom vis-a-vis the use of technologies. Three main mechanisms that…

Technological Determinism in Educational Technology Research: Some Alternative Ways of Thinking about the Relationship between Learning and Technology

ERIC Educational Resources Information Center

Oliver, M.

2011-01-01

This paper argues that research on the educational uses of technology frequently overemphasizes the influence of technology. Research in the field is considered a form of critical perspective, and assumptions about technology are questioned. Technological determinism is introduced, and different positions on this concept are identified. These are…

Applications of aerospace technology in industry. A technology transfer profile: Food technology

NASA Technical Reports Server (NTRS)

Murray, D. M.

1971-01-01

Food processing and preservation technologies are reviewed, expected technological advances are considered including processing and market factors. NASA contributions to food technology and nutrition are presented with examples of transfer from NASA to industry.

Decision Gate Process for Assessment of a NASA Technology Development Portfolio

NASA Technical Reports Server (NTRS)

Kohli, Rajiv; Fishman, Julianna L.; Hyatt, Mark J.

2012-01-01

The NASA Dust Management Project (DMP) was established to provide technologies (to Technology Readiness Level (TRL) 6) required to address adverse effects of lunar dust to humans and to exploration systems and equipment, to reduce life cycle cost and risk, and to increase the probability of sustainable and successful lunar missions. The technology portfolio of DMP consisted of different categories of technologies whose final product was either a technology solution in itself, or one that contributes toward a dust mitigation strategy for a particular application. A Decision Gate Process (DGP) was developed to assess and validate the achievement and priority of the dust mitigation technologies as the technologies progress through the development cycle. The DGP was part of continuous technology assessment and was a critical element of DMP risk management. At the core of the process were technology-specific criteria developed to measure the success of each DMP technology in attaining the technology readiness levels assigned to each decision gate. The DGP accounts for both categories of technologies and qualifies the technology progression from technology development tasks to application areas. The process provided opportunities to validate performance, as well as to identify non-performance in time to adjust resources and direction. This paper describes the overall philosophy of the DGP and the methodology for implementation for DMP, and describes the method for defining the technology evaluation criteria. The process is illustrated by example of an application to a specific DMP technology.

Educational technology in medical education.

PubMed

Han, Heeyoung; Resch, David S; Kovach, Regina A

2013-01-01

This article aims to review the past practices of educational technology and envision future directions for medical education. The discussion starts with a historical review of definitions and perspectives of educational technology, in which the authors propose that educators adopt a broader process-oriented understanding of educational technology. Future directions of e-learning, simulation, and health information technology are discussed based on a systems view of the technological process. As new technologies continue to arise, this process-oriented understanding and outcome-based expectations of educational technology should be embraced. With this view, educational technology should be valued in terms of how well the technological process informs and facilitates learning, and the acquisition and maintenance of clinical expertise.

Analysis of the frontier technology of agricultural IoT and its predication research

NASA Astrophysics Data System (ADS)

Han, Shuqing; Zhang, Jianhua; Zhu, Mengshuai; Wu, Jianzhai; Shen, Chen; Kong, Fantao

2017-09-01

Agricultural IoT (Internet of Things) develops rapidly. Nanotechnology, biotechnology and optoelectronic technology are successfully integrated into the agricultural sensor technology. Big data, cloud computing and artificial intelligence technology have also been successfully used in IoT. This paper carries out the research on integration of agricultural sensor technology, nanotechnology, biotechnology and optoelectronic technology and the application of big data, cloud computing and artificial intelligence technology in agricultural IoT. The advantages and development of the integration of nanotechnology, biotechnology and optoelectronic technology with agricultural sensor technology were discussed. The application of big data, cloud computing and artificial intelligence technology in IoT and their development trend were analysed.

Analysis of Impact of 3D Printing Technology on Traditional Manufacturing Technology

NASA Astrophysics Data System (ADS)

Wu, Niyan; Chen, Qi; Liao, Linzhi; Wang, Xin

With quiet rise of 3D printing technology in automobile, aerospace, industry, medical treatment and other fields, many insiders hold different opinions on its development. This paper objectively analyzes impact of 3D printing technology on mold making technology and puts forward the idea of fusion and complementation of 3D printing technology and mold making technology through comparing advantages and disadvantages of 3D printing mold and traditional mold making technology.

NASA Technology Transfer System

NASA Technical Reports Server (NTRS)

Tran, Peter B.; Okimura, Takeshi

2017-01-01

NTTS is the IT infrastructure for the Agency's Technology Transfer (T2) program containing 60,000+ technology portfolio supporting all ten NASA field centers and HQ. It is the enterprise IT system for facilitating the Agency's technology transfer process, which includes reporting of new technologies (e.g., technology invention disclosures NF1679), protecting intellectual properties (e.g., patents), and commercializing technologies through various technology licenses, software releases, spinoffs, and success stories using custom built workflow, reporting, data consolidation, integration, and search engines.

An assessment of producer precision dairy farming technology use, prepurchase considerations, and usefulness.

PubMed

Borchers, M R; Bewley, J M

2015-06-01

An online survey to identify producer precision dairy farming technology perception was distributed in March 2013 through web links sent to dairy producers through written publications and e-mail. Responses were collected in May 2013 and 109 surveys were used in statistical analysis. Producers were asked to select parameters monitored by technologies on their farm from a predetermined list and 68.8% of respondents indicated technology use on their dairies (31.2% of producers not using technologies). Daily milk yield (52.3%), cow activity (41.3%), and mastitis (25.7%) were selected most frequently. Producers were also asked to score the same list of parameters on usefulness using a 5-point scale (1=not useful and 5=useful). Producers indicated (mean ± SE) mastitis (4.77±0.47), standing estrus (4.75±0.55), and daily milk yield (4.72±0.62) to be most useful. Producers were asked to score considerations taken before deciding to purchase a precision dairy farming technology from a predetermined list (1=not important and 5=important). Producers indicated benefit-to-cost ratio (4.57±0.66), total investment cost (4.28±0.83), and simplicity and ease of use (4.26±0.75) to be most important when deciding whether to implement a technology. Producers were categorized based on technology use (using technology vs. not using technology) and differed significantly across technology usefulness scores, daily milk yield (using technologies: 4.83±0.07 vs. not using technologies: 4.50±0.10), and standing estrus (using technologies: 4.68±0.06 vs. not using technologies: 4.91±0.09). The same categories were used to evaluate technology use effect on prepurchase technology selection criteria and availability of local support (using technologies: 4.25±0.11 vs. not using technologies: 3.82±0.16) differed significantly. Producer perception of technology remains relatively unknown to manufacturers. Using this data, technology manufacturers may better design and market technologies to producer need. Copyright © 2015 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Strategic Planning for Technological Change

ERIC Educational Resources Information Center

Strong, Bart

2007-01-01

Strategic planning can become downright treacherous if one's institution depends heavily on technology, because technology changes course frequently. Technological change is somewhat predictable, and doing nothing is not an option. A number of complex factors hasten technological change. Limits on performance, breakthrough technology, market…

77 FR 5282 - National Science and Technology Council

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-02

... OFFICE OF SCIENCE AND TECHNOLOGY POLICY National Science and Technology Council ACTION: Notice of... Nanoscale Science, Engineering, and Technology (NSET) Subcommittee of the Committee on Technology, National Science and Technology Council (NSTC), will hold an ``International Symposium on Assessing the Economic...

Cost, Time, and Risk Assessment of Different Wave Energy Converter Technology Development Trajectories: Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weber, Jochem W; Laird, Daniel; Costello, Ronan

This paper presents a comparative assessment of three fundamentally different wave energy converter technology development trajectories. The three technology development trajectories are expressed and visualised as a function of technology readiness levels and technology performance levels. The assessment shows that development trajectories that initially prioritize technology readiness over technology performance are likely to require twice the development time, consume a threefold of the development cost, and are prone to a risk of technical or commercial failure of one order of magnitude higher than those development trajectories that initially prioritize technology performance over technology readiness.

The Status of Spacecraft Bus and Platform Technology Development under the NASA ISPT Program

NASA Technical Reports Server (NTRS)

Anderson, David J.; Munk, Michelle M.; Pencil, Eric; Dankanich, John; Glaab, Louis; Peterson, Todd

2013-01-01

The In-Space Propulsion Technology (ISPT) program is developing spacecraft bus and platform technologies that will enable or enhance NASA robotic science missions. The ISPT program is currently developing technology in four areas that include Propulsion System Technologies (electric and chemical), Entry Vehicle Technologies (aerocapture and Earth entry vehicles), Spacecraft Bus and Sample Return Propulsion Technologies (components and ascent vehicles), and Systems/Mission Analysis. Three technologies are ready for near-term flight infusion: 1) the high-temperature Advanced Material Bipropellant Rocket (AMBR) engine providing higher performance; 2) NASA s Evolutionary Xenon Thruster (NEXT) ion propulsion system, a 0.6-7 kW throttle-able gridded ion system; and 3) Aerocapture technology development with investments in a family of thermal protection system (TPS) materials and structures; guidance, navigation, and control (GN&C) models of blunt-body rigid aeroshells; and aerothermal effect models. Two component technologies being developed with flight infusion in mind are the Advanced Xenon Flow Control System and ultralightweight propellant tank technologies. Future directions for ISPT are technologies that relate to sample return missions and other spacecraft bus technology needs like: 1) Mars Ascent Vehicles (MAV); 2) multi-mission technologies for Earth Entry Vehicles (MMEEV); and 3) electric propulsion. These technologies are more vehicles and mission-focused, and present a different set of technology development and infusion steps beyond those previously implemented. The Systems/Mission Analysis area is focused on developing tools and assessing the application of propulsion and spacecraft bus technologies to a wide variety of mission concepts. These inspace propulsion technologies are applicable, and potentially enabling for future NASA Discovery, New Frontiers, and sample return missions currently under consideration, as well as having broad applicability to potential Flagship missions. This paper provides a brief overview of the ISPT program, describing the development status and technology infusion readiness of in-space propulsion technologies in the areas of electric propulsion, Aerocapture, Earth entry vehicles, propulsion components, Mars ascent vehicle, and mission/systems analysis.

The status of spacecraft bus and platform technology development under the NASA ISPT program

NASA Astrophysics Data System (ADS)

Anderson, D. J.; Munk, M. M.; Pencil, E.; Dankanich, J.; Glaab, L.; Peterson, T.

The In-Space Propulsion Technology (ISPT) program is developing spacecraft bus and platform technologies that will enable or enhance NASA robotic science missions. The ISPT program is currently developing technology in four areas that include Propulsion System Technologies (electric and chemical), Entry Vehicle Technologies (aerocapture and Earth entry vehicles), Spacecraft Bus and Sample Return Propulsion Technologies (components and ascent vehicles), and Systems/Mission Analysis. Three technologies are ready for near-term flight infusion: 1) the high-temperature Advanced Material Bipropellant Rocket (AMBR) engine providing higher performance; 2) NASA's Evolutionary Xenon Thruster (NEXT) ion propulsion system, a 0.6-7 kW throttle-able gridded ion system; and 3) Aerocapture technology development with investments in a family of thermal protection system (TPS) materials and structures; guidance, navigation, and control (GN& C) models of blunt-body rigid aeroshells; and aerothermal effect models. Two component technologies being developed with flight infusion in mind are the Advanced Xenon Flow Control System and ultra-lightweight propellant tank technologies. Future directions for ISPT are technologies that relate to sample return missions and other spacecraft bus technology needs like: 1) Mars Ascent Vehicles (MAV); 2) multi-mission technologies for Earth Entry Vehicles (MMEEV); and 3) electric propulsion. These technologies are more vehicles and mission-focused, and present a different set of technology development and infusion steps beyond those previously implemented. The Systems/Mission Analysis area is focused on developing tools and assessing the application of propulsion and spacecraft bus technologies to a wide variety of mission concepts. These in-space propulsion technologies are applicable, and potentially enabling for future NASA Discovery, New Frontiers, and sample return missions currently under consideration, as well as having broad applicabilit- to potential Flagship missions. This paper provides a brief overview of the ISPT program, describing the development status and technology infusion readiness of in-space propulsion technologies in the areas of electric propulsion, Aerocapture, Earth entry vehicles, propulsion components, Mars ascent vehicle, and mission/systems analysis.

The Status of Spacecraft Bus and Platform Technology Development Under the NASA ISPT Program

NASA Technical Reports Server (NTRS)

Anderson, David; Munk, Michelle M.; Pencil, Eric; Dankanich, John; Glaab, Louis; Peterson, Todd

2014-01-01

The In-Space Propulsion Technology (ISPT) program is developing spacecraft bus and platform technologies that will enable or enhance NASA robotic science missions. The ISPT program is currently developing technology in three areas that include Propulsion System Technologies, Entry Vehicle Technologies, and Systems Mission Analysis. ISPTs propulsion technologies include: 1) NASAs Evolutionary Xenon Thruster (NEXT) ion propulsion system, a 0.6-7 kW throttle-able gridded ion system; 2) a Hall-effect electric propulsion (HEP) system for sample return and low cost missions; 3) the Advanced Xenon Flow Control System (AXFS); ultra-lightweight propellant tank technologies (ULTT); and propulsion technologies for a Mars Ascent Vehicle (MAV). The AXFS and ULTT are two component technologies being developed with nearer-term flight infusion in mind, whereas NEXT and the HEP are being developed as EP systems. ISPTs entry vehicle technologies are: 1) Aerocapture technology development with investments in a family of thermal protection system (TPS) materials and structures; guidance, navigation, and control (GNC) models of blunt-body rigid aeroshells; and aerothermal effect models; and 2) Multi-mission technologies for Earth Entry Vehicles (MMEEV) for sample return missions. The Systems Mission Analysis area is focused on developing tools and assessing the application of propulsion, entry vehicle, and spacecraft bus technologies to a wide variety of mission concepts. Several of the ISPT technologies are related to sample return missions and other spacecraft bus technology needs like: MAV propulsion, MMEEV, and electric propulsion. These technologies, as well as Aerocapture, are more vehicle and mission-focused, and present a different set of technology development challenges. These in-space propulsion technologies are applicable, and potentially enabling for future NASA Discovery, New Frontiers, Flagship and sample return missions currently under consideration. This paper provides a brief overview of the ISPT program, describing the development status and technology infusion readiness.

The Status of Spacecraft Bus and Platform Technology Development Under the NASA ISPT Program

NASA Technical Reports Server (NTRS)

Anderson, David J.; Munk, Michelle M.; Pencil, Eric J.; Dankanich, John; Glaab, Louis J.

2013-01-01

The In-Space Propulsion Technology (ISPT) program is developing spacecraft bus and platform technologies that will enable or enhance NASA robotic science missions. The ISPT program is currently developing technology in four areas that include Propulsion System Technologies (electric and chemical), Entry Vehicle Technologies (aerocapture and Earth entry vehicles), Spacecraft Bus and Sample Return Propulsion Technologies (components and ascent vehicles), and Systems/Mission Analysis. Three technologies are ready for near-term flight infusion: 1) the high-temperature Advanced Material Bipropellant Rocket (AMBR) engine providing higher performance 2) NASAs Evolutionary Xenon Thruster (NEXT) ion propulsion system, a 0.6-7 kW throttle-able gridded ion system and 3) Aerocapture technology development with investments in a family of thermal protection system (TPS) materials and structures guidance, navigation, and control (GN&C) models of blunt-body rigid aeroshells and aerothermal effect models. Two component technologies being developed with flight infusion in mind are the Advanced Xenon Flow Control System, and ultra-lightweight propellant tank technologies. Future direction for ISPT are technologies that relate to sample return missions and other spacecraft bus technology needs like: 1) Mars Ascent Vehicles (MAV) 2) multi-mission technologies for Earth Entry Vehicles (MMEEV) and 3) electric propulsion. These technologies are more vehicle and mission-focused, and present a different set of technology development and infusion steps beyond those previously implemented. The Systems/Mission Analysis area is focused on developing tools and assessing the application of propulsion and spacecraft bus technologies to a wide variety of mission concepts. These in-space propulsion technologies are applicable, and potentially enabling for future NASA Discovery, New Frontiers, and sample return missions currently under consideration, as well as having broad applicability to potential Flagship missions. This paper provides a brief overview of the ISPT program, describing the development status and technology infusion readiness of in-space propulsion technologies in the areas of electric propulsion, Aerocapture, Earth entry vehicles, propulsion components, Mars ascent vehicle, and mission/systems analysis.

SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 5: Human Support

NASA Technical Reports Server (NTRS)

1991-01-01

Viewgraphs of briefings from the Space Systems and Technology Advisory Committee (SSTAC)/ARTS review of the draft integrated technology plan (ITP) on human support are included. Topics covered include: human support program; human factors; life support technology; fire safety; medical support technology; advanced refrigeration technology; EVA suit system; advanced PLSS technology; and ARC-EVA systems research program.

Preparing Teachers to Integrate Technology into K-12 Instruction: Comparing a Stand-Alone Technology Course with a Technology-Infused Approach

ERIC Educational Resources Information Center

Buss, Ray R.; Wetzel, Keith; Foulger, Teresa S.; Lindsey, LeeAnn

2015-01-01

We compared the effectiveness of learning technological, pedagogical, and content knowledge (TPACK) domain knowledge in a new technology-infused approach for teaching technology to teacher candidates with a more traditional, stand-alone course. In the new approach, learning to use technology is infused into program methods courses. Candidates all…

Technological Literacy for All: A Course Designed to Raise the Technological Literacy of College Students

ERIC Educational Resources Information Center

Baskette, Kimberly G.; Fantz, Todd D.

2013-01-01

Understanding what technology is, and is not, is the first step in becoming technologically literate. One should also understand how technology is created, how it works, how it shapes society, and how society shapes technology. This study was designed to gauge the ability of a single-semester course to raise students' technological literacy as…

Some Implications of the Philosophy of Technology for Science, Technology and Society (STS) Studies

ERIC Educational Resources Information Center

Ankiewicz, Piet; De Swardt, Estelle; De Vries, Marc

2006-01-01

Technology is frequently considered in terms of its impact on entities outside its essential nature: as the impact of technology on the environment and society, but also the impact of human values and needs on technology. By taking particular social implications of technology into account, the Science-Technology relationship can be extended to the…

Nature of Technology: Implications for design, development, and enactment of technological tools in school science classrooms

NASA Astrophysics Data System (ADS)

Waight, Noemi; Abd-El-Khalick, Fouad

2012-12-01

This position paper provides a theory-based explanation informed by philosophy of technology (PoT) of the recurrent documented patterns often associated with attempts to enact technology-supported, inquiry-based approaches in precollege science classrooms. Understandings derived from the history of technological development in other domains (e.g. medicine, transportation, and warfare) reveal numerous parallels that help to explain these recurrent patterns. Historical analyses of major technologies reveal a conglomerate of factors that interact to produce benefits, as well as intended and unintended consequences. On a macro-scale, PoT facilitates understandings of how technologies interact and are impacted by individuals, society, institutions, economy, politics, and culture. At the micro-level, and most relevant to science education, PoT engages the inherent nature of technology along a number of key dimensions: role of culture and values, notions of technological progression, technology as part of systems, technological diffusion, technology as a fix, and the notions of expertise. Overall, the present analysis has implications for the design, development, implementation, and adoption of technological tools for use in precollege science education, and highlights the role of technology as both artifact and process.

Technology Adoption: an Interaction Perspective

NASA Astrophysics Data System (ADS)

Sitorus, Hotna M.; Govindaraju, Rajesri; Wiratmadja, I. I.; Sudirman, Iman

2016-02-01

The success of a new technology depends on how well it is accepted by its intended users. Many technologies face the problem of low adoption rate, despite the benefits. An understanding of what makes people accept or reject a new technology can help speed up the adoption rate. This paper presents a framework for technology adoption based on an interactive perspective, resulting from a literature study on technology adoption. In studying technology adoption, it is necessary to consider the interactions among elements involved in the system, for these interactions may generate new characteristics or new relationships. The interactions among elements in a system adoption have not received sufficient consideration in previous studies of technology adoption. Based on the proposed interaction perspective, technology adoption is elaborated by examining interactions among the individual (i.e. the user or prospective user), the technology, the task and the environment. The framework is formulated by adopting several theories, including Perceived Characteristics of Innovating, Diffusion of Innovation Theory, Technology Acceptance Model, Task-Technology Fit and usability theory. The proposed framework is illustrated in the context of mobile banking adoption. It is aimed to offer a better understanding of determinants of technology adoption in various contexts, including technology in manufacturing systems.

Commercializing Defense Technologies and Helping Defense Firms Succeed in Commercial Markets: A Report on the Objectives, Activities, and Accomplishments of the TAP-IN Program

NASA Technical Reports Server (NTRS)

1997-01-01

Technology Access for Product Innovation (TAP-IN), the largest technology deployment project funded by TRP, was competitively selected through a national solicitation for proposals. TAP-IN was created to help companies access and apply defense technologies and help defense-dependent companies enter new commercial markets. Defense technologies included technologies developed by DoD, DOE, NASA, and their contractors. TAP-IN was structured to provide region-based technology access services that were able to draw on technology resources nationwide. TAP-IN provided expert assistance in all stages of the commercialization process from concept through prototype design to capital sourcing and marketing strategy. TAP-IN helped companies locate new technology, identify business partners, secure financing, develop ideas for new products, identify new markets, license technology, solve technical problems, and develop company-specific applications of federal technology. TAP-IN leveraged NASA's existing commercial technology network to create an integrated national network of organizations that assisted companies in every state. In addition to NASA's six regional technology transfer centers (RTTCs), TAP-IN included business and technology development organizations in every state, the Industrial Designers Society of America, and the Federal Laboratory Consortium (FLC).

Technology CAD for integrated circuit fabrication technology development and technology transfer

NASA Astrophysics Data System (ADS)

Saha, Samar

2003-07-01

In this paper systematic simulation-based methodologies for integrated circuit (IC) manufacturing technology development and technology transfer are presented. In technology development, technology computer-aided design (TCAD) tools are used to optimize the device and process parameters to develop a new generation of IC manufacturing technology by reverse engineering from the target product specifications. While in technology transfer to manufacturing co-location, TCAD is used for process centering with respect to high-volume manufacturing equipment of the target manufacturing equipment of the target manufacturing facility. A quantitative model is developed to demonstrate the potential benefits of the simulation-based methodology in reducing the cycle time and cost of typical technology development and technology transfer projects over the traditional practices. The strategy for predictive simulation to improve the effectiveness of a TCAD-based project, is also discussed.

Assessment of US industry's technology trends and new technology requirements

NASA Technical Reports Server (NTRS)

1984-01-01

The utility and effectiveness of a novel approach (the Applications Development, or AD approach), intended to augment the efficiency of NASA's technology utilization (TU) through dissemination of NASA technologies and joint technology development efforts with U.S. industry is tested. The innovative AD approach consists of the following key elements: selection of NASA technologies appearing to have leading edge attributes; interaction with NASA researchers to assess the characteristics and quality of each selected technology; identification of industry's needs in the selected technology areas; structuring the selected technologies in terms of specifications and standards familiar to industry (industrial Spec. Sheets); identification and assessment of industry's interest in the specific selected NASA technologies, utilizing the greatly facilitated communication made possible by the availability of the industrial Spec. Sheets; and matching selected NASA technologies with the needs of selected industries.

Assistive Technology. NICHCY News Digest.

ERIC Educational Resources Information Center

Horne, Richard, Ed.

The newsletter presents six articles and associated information concerned with assistive technology for children and youth with handicaps. "Technology: Becoming an Informed Consumer" (Elizabeth Lahm and Sue Elting) reviews the history of technology with emphasis on assistive technology, offers case studies on technology applications, and gives…

Information Communication Technology Planning in Developing Countries

ERIC Educational Resources Information Center

Malapile, Sandy; Keengwe, Jared

2014-01-01

This article explores major issues related to Information Communication Technology (ICT) in education and technology planning. Using the diffusion of innovation theory, the authors examine technology planning opportunities and challenges in Developing countries (DCs), technology planning trends in schools, and existing technology planning models…

Technology Alignment and Portfolio Prioritization (TAPP)

NASA Technical Reports Server (NTRS)

Funaro, Gregory V.; Alexander, Reginald A.

2015-01-01

Technology Alignment and Portfolio Prioritization (TAPP) is a method being developed by the Advanced Concepts Office, at NASA Marshall Space Flight Center. The TAPP method expands on current technology assessment methods by incorporating the technological structure underlying technology development, e.g., organizational structures and resources, institutional policy and strategy, and the factors that motivate technological change. This paper discusses the methods ACO is currently developing to better perform technology assessments while taking into consideration Strategic Alignment, Technology Forecasting, and Long Term Planning.

The southern regional conference on technology assessment: Summary

NASA Technical Reports Server (NTRS)

Coates, V. T.; Mock, J. E.

1974-01-01

The proceedings of a conference on technology assessment are presented. A survey of recent Federal activity in technology assessment was discussed initially. Emphasis was placed on state and local activities with respect to technology assessment to include the following subjects: (1) the technology assessment desired by states, (2) organization of technology assessment activities, (3) how to perform technology assessments for less than $5,000, and (4) the preparation of environmental impact statements. Specific application of technology assessment to solid waste management in Connecticut is reported.

NASA's Microgravity Technology Report, 1996: Summary of Activities

NASA Technical Reports Server (NTRS)

Kierk, Isabella

1996-01-01

This report covers technology development and technology transfer activities within the Microgravity Science Research Programs during FY 1996. It also describes the recent major tasks under the Advanced Technology Development (ATD) Program and identifies current technology requirements. This document is consistent with NASA,s Enteprise for the Human Exploration and development of Space (HEDS) Strategic Plan. This annual update reflects changes in the Microgravity Science Research Program's new technology activities and requirements. Appendix A. FY 1996 Advanced Technology Development. Program and Project Descriptions. Appendix B. Technology Development.

The interface of genomic technologies and nursing.

PubMed

Loescher, Lois J; Merkle, Carrie J

2005-01-01

(a) to summarize views of the interface of technology, genomic technology, and nursing; (b) provide an overview of current and emerging genomic technologies; (c) present clinical exemplars of uses of genomic technology in two disease conditions; and (d) list genomic-focused nursing research on genomic technologies. A discussion of genomic technology in the context of nurses' views of technology, the importance of genomic technology for nurses, linking the central dogma of molecular biology to state-of-the-art tests and assays, and nurses' current use of technologies. Human genome discoveries will continue to be an integral part of disease prevention, diagnosis, treatment, and management. These discoveries also have the potential for being integrated into nursing science. Genomic technologies are becoming a driving force in patient management, so that nurses will be unable to provide quality care without knowledge of the types of genomic technologies, the rationale for their use, and the possible sequelae that can result from genetic diagnosis or treatment. Many nurses already are using genomic technologies to conduct genomic-focused nursing research. The biobehavioral nature of much of this research further indicates the important contributions of nurses in genomics.

A network meta-analysis on the effects of information technology application on preoperative knowledge of patients.

PubMed

Lai, Yi-Horng

2015-01-01

The application of information technology in health education plan in Taiwan has existed for a long time. The purpose of this study is to explore the relationship between information technology application in health education and patients' preoperative knowledge by synthesizing existing researches that compare the effectiveness of information technology application and traditional instruction in the health education plan. In spite of claims regarding the potential benefits of using information technology in health education plan, results of previous researches were conflicting. This study is carried out to examine the effectiveness of information technology by using network meta-analysis, which is a statistical analysis of separate but similar studies in order to test the pooled data for statistical significance. Information technology application in health education discussed in this study include interactive technology therapy (person-computer), group interactive technology therapy (person-person), multimedia technology therapy and video therapy. The result has shown that group interactive technology therapy is the most effective, followed by interactive technology therapy. And these four therapies of information technology are all superior to the traditional health education plan (leaflet therapy).

System analysis for technology transfer readiness assessment of horticultural postharvest

NASA Astrophysics Data System (ADS)

Hayuningtyas, M.; Djatna, T.

2018-04-01

Availability of postharvest technology is becoming abundant, but only a few technologies are applicable and useful to a wider community purposes. Based on this problem it requires a significant readiness level of transfer technology approach. This system is reliable to access readiness a technology with level, from 1-9 and to minimize time of transfer technology in every level, time required technology from the selection process can be minimum. Problem was solved by using Relief method to determine ranking by weighting feasible criteria on postharvest technology in each level and PERT (Program Evaluation Review Technique) to schedule. The results from ranking process of post-harvest technology in the field of horticulture is able to pass level 7. That, technology can be developed to increase into pilot scale and minimize time required for technological readiness on PERT with optimistic time of 7,9 years. Readiness level 9 shows that technology has been tested on the actual conditions also tied with estimated production price compared to competitors. This system can be used to determine readiness of technology innovation that is derived from agricultural raw materials and passes certain stages.

Different Perspectives on Technology Acceptance: The Role of Technology Type and Age

NASA Astrophysics Data System (ADS)

Arning, Katrin; Ziefle, Martina

Although eHealth technologies offer an enormous potential to improve healthcare, the knowledge about key determinants of acceptance for eHealth technology is restricted. While the underlying technology of eHealth technologies and Information and Communication technology (ICT) is quite similar, utilization contexts and using motives are quite different. In order to explore the role of technology type on acceptance, we contrasted central application characteristics of both technology types using the scenario technique. A questionnaire was administered (n = 104) measuring individual variables (age, gender) and attitudes regarding an eHealth application (blood sugar meter) in contrast to an ICT device (Personal Digital Assistant, PDA). Older users basically approved the utilization of health-related technologies and perceived lower usability barriers. In addition, we identified main utilization motives of eHealth technology and technology-specific acceptance patterns, especially regarding issues of data safety in the eHealth context. Effects of age and gender in acceptance ratings suggest a differential perspective on eHealth acceptance. Finally, practical interventions were derived in order to support eHealth device design and to promote acceptance of eHealth technology.

Disruptive Technology: An Uncertain Future

DTIC Science & Technology

2005-05-21

Technology that overturns market -- Military - Technology that causes a fundamental change in force structure, basing, and capability balance * Disruptive Technologies may arise from systems or enabling technology.

Rapid Prototyping Technologies for Manufacturing and Maintenance Activities

NASA Astrophysics Data System (ADS)

Pfeifer, Marcel Rolf

2017-12-01

The paper deals with the direct application of Rapid Prototyping technologies for parts and spare parts production in production companies and the economic effect by making use of this technology. Traditional production technologies are technologies such as forging, cutting, machining, etc. These technologies are widely accepted and the teething troubles are solved. Rapid Prototyping technologies such as 3D printing on the other hand came into the focus in the recent years when the technologies and the produced quality gradually advanced. Providing flexibility and time efficiency the technology should also have a practical application in production. This paper has the aim to provide a case-study based on existing cost figures to show that these technologies are not limited to prototype developments.

Advanced Refrigerator/Freezer Technology Development. Technology Assessment

NASA Technical Reports Server (NTRS)

Gaseor, Thomas; Hunter, Rick; Hamill, Doris

1996-01-01

The NASA Lewis Research Center, through contract with Oceaneering Space Systems, is engaged in a project to develop advanced refrigerator/freezer (R/F) technologies for future Life and Biomedical Sciences space flight missions. The first phase of this project, a technology assessment, has been completed to identify the advanced R/F technologies needed and best suited to meet the requirements for the five R/F classifications specified by Life and Biomedical Science researchers. Additional objectives of the technology assessment were to rank those technologies based on benefit and risk, and to recommend technology development activities that can be accomplished within this project. This report presents the basis, the methodology, and results of the R/F technology assessment, along with technology development recommendations.

Software Engineering Technology Infusion Within NASA

NASA Technical Reports Server (NTRS)

Zelkowitz, Marvin V.

1996-01-01

Abstract technology transfer is of crucial concern to both government and industry today. In this paper, several software engineering technologies used within NASA are studied, and the mechanisms, schedules, and efforts at transferring these technologies are investigated. The goals of this study are: 1) to understand the difference between technology transfer (the adoption of a new method by large segments of an industry) as an industry-wide phenomenon and the adoption of a new technology by an individual organization (called technology infusion); and 2) to see if software engineering technology transfer differs from other engineering disciplines. While there is great interest today in developing technology transfer models for industry, it is the technology infusion process that actually causes changes in the current state of the practice.

Transportation technology program: Strategic plan

NASA Astrophysics Data System (ADS)

1991-09-01

The purpose of this report is to define the technology program required to meet the transportation technology needs for current and future civil space missions. It is a part of an integrated plan, prepared by NASA in part in response to the Augustine Committee recommendations, to describe and advocate expanded and more aggressive efforts in the development of advanced space technologies. This expanded program will provide a technology basis for future space missions to which the U.S. aspires, and will help to regain technology leadership for the U.S. on a broader front. The six aspects of this integrated program/plan deal with focused technologies to support space sciences, exploration, transportation, platforms, and operations as well as provide a Research and Technology Base Program. This volume describes the technologies needed to support transportation systems, e.g., technologies needed for upgrades to current transportation systems and to provide reliable and efficient transportation for future space missions. The Office of Aeronautics, Exploration, and Technology (OAET) solicited technology needs from the major agency technology users and the aerospace industry community and formed a transportation technology team (appendix A) to develop a technology program to respond to those needs related to transportation technologies. This report addresses the results of that team activity. It is a strategic plan intended for use as a planning document rather than as a project management tool. It is anticipated that this document will be primarily utilized by research & technology (R&T) management at the various NASA Centers as well as by officials at NASA Headquarters and by industry in planning their corporate Independent Research and Development (IR&D) investments.

Transportation technology program: Strategic plan

NASA Technical Reports Server (NTRS)

1991-01-01

The purpose of this report is to define the technology program required to meet the transportation technology needs for current and future civil space missions. It is a part of an integrated plan, prepared by NASA in part in response to the Augustine Committee recommendations, to describe and advocate expanded and more aggressive efforts in the development of advanced space technologies. This expanded program will provide a technology basis for future space missions to which the U.S. aspires, and will help to regain technology leadership for the U.S. on a broader front. The six aspects of this integrated program/plan deal with focused technologies to support space sciences, exploration, transportation, platforms, and operations as well as provide a Research and Technology Base Program. This volume describes the technologies needed to support transportation systems, e.g., technologies needed for upgrades to current transportation systems and to provide reliable and efficient transportation for future space missions. The Office of Aeronautics, Exploration, and Technology (OAET) solicited technology needs from the major agency technology users and the aerospace industry community and formed a transportation technology team (appendix A) to develop a technology program to respond to those needs related to transportation technologies. This report addresses the results of that team activity. It is a strategic plan intended for use as a planning document rather than as a project management tool. It is anticipated that this document will be primarily utilized by research & technology (R&T) management at the various NASA Centers as well as by officials at NASA Headquarters and by industry in planning their corporate Independent Research and Development (IR&D) investments.

Technology in Science and Mathematics Education.

ERIC Educational Resources Information Center

Buccino, Alphonse

Provided are several perspectives on technology, addressing changes in learners related to technology, changes in contemporary life related to technology, and changes in subject areas related to technology (indicating that technology has created such new tools for inquiry as computer programming, word processing, online database searches, and…

Technology Usage of Tennessee Agriculture Teachers

ERIC Educational Resources Information Center

Coley, Michael D.; Warner, Wendy J.; Stair, Kristin S.; Flowers, James L.; Croom, D. Barry

2015-01-01

This study examined the accessibility and use of instructional technologies by agriculture teachers in Tennessee. Data were collected using a survey instrument to investigate teachers' adoption of technology, sources of acquired technology skills, accessibility and use of technological equipment, and barriers to technology integration. The study…

ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT: ECR TECHNOLOGIES, INC., EARTHLINKED GROUND-SOURCE HEAT PUMP WATER HEATING SYSTEM

EPA Science Inventory

EPA has created the Environmental Technology Verification program to provide high quality, peer reviewed data on technology performance. This data is expected to accelerate the acceptance and use of improved environmental protection technologies. The Greenhouse Gas Technology C...

40 CFR 420.03 - Alternative effluent limitations representing the degree of effluent reduction attainable by the...

Code of Federal Regulations, 2011 CFR

2011-07-01

... technology currently available, best available technology economically achievable, best available demonstrated control technology, and best conventional pollutant control technology (the âwater bubbleâ). 420... of best practicable control technology currently available, best available technology economically...

40 CFR 420.03 - Alternative effluent limitations representing the degree of effluent reduction attainable by the...

Code of Federal Regulations, 2012 CFR

2012-07-01

... technology currently available, best available technology economically achievable, best available demonstrated control technology, and best conventional pollutant control technology (the âwater bubbleâ). 420... of best practicable control technology currently available, best available technology economically...

40 CFR 420.03 - Alternative effluent limitations representing the degree of effluent reduction attainable by the...

Code of Federal Regulations, 2010 CFR

2010-07-01

... technology currently available, best available technology economically achievable, best available demonstrated control technology, and best conventional pollutant control technology (the âwater bubbleâ). 420... of best practicable control technology currently available, best available technology economically...

Swiss and Turkish Pre-Service Science Teachers' Anxiety Levels for Educational Technology

ERIC Educational Resources Information Center

Efe, Hulya Aslan; Efe, Rifat

2016-01-01

This study aims to culturally explain pre-service science teachers' instructional technology-related anxiety levels by analyzing the variables of their instructional technology using experiences, frequency of using instructional technologies, access to instructional technologies, instructional technology-related attitude and their instructional…

Older Adults Talk Technology: Technology Usage and Attitudes.

PubMed

Mitzner, Tracy L; Boron, Julie B; Fausset, Cara Bailey; Adams, Anne E; Charness, Neil; Czaja, Sara J; Dijkstra, Katinka; Fisk, Arthur D; Rogers, Wendy A; Sharit, Joseph

2010-11-01

Older adults (n = 113) participated in focus groups discussing their use of and attitudes about technology in the context of their home, work, and healthcare. Participants reported using a wide variety of technology items, particularly in their homes. Positive attitudes (i.e., likes) outnumbered negative attitudes (i.e., dislikes), suggesting that older adults perceive the benefits of technology use to outweigh the costs of such use. Positive attitudes were most frequently related to how the technology supported activities, enhanced convenience, and contained useful features. Negative attitudes were most frequently associated with technology creating inconveniences, unhelpful features, as well as security and reliability concerns. Given that older adults reported more positive than negative attitudes about the technologies they use, these results contradict stereotypes that older adults are afraid or unwilling to use technology. These findings also highlight the importance of perceived benefits of use and ease of use for models of technology acceptance. Emphasizing the benefits of technology in education and training programs may increase future technology adoption.

Older Adults Talk Technology: Technology Usage and Attitudes

PubMed Central

Mitzner, Tracy L.; Boron, Julie B.; Fausset, Cara Bailey; Adams, Anne E.; Charness, Neil; Czaja, Sara J.; Dijkstra, Katinka; Fisk, Arthur D.; Rogers, Wendy A.; Sharit, Joseph

2010-01-01

Older adults (n = 113) participated in focus groups discussing their use of and attitudes about technology in the context of their home, work, and healthcare. Participants reported using a wide variety of technology items, particularly in their homes. Positive attitudes (i.e., likes) outnumbered negative attitudes (i.e., dislikes), suggesting that older adults perceive the benefits of technology use to outweigh the costs of such use. Positive attitudes were most frequently related to how the technology supported activities, enhanced convenience, and contained useful features. Negative attitudes were most frequently associated with technology creating inconveniences, unhelpful features, as well as security and reliability concerns. Given that older adults reported more positive than negative attitudes about the technologies they use, these results contradict stereotypes that older adults are afraid or unwilling to use technology. These findings also highlight the importance of perceived benefits of use and ease of use for models of technology acceptance. Emphasizing the benefits of technology in education and training programs may increase future technology adoption. PMID:20967133

Patient source of learning about health technologies and ratings of trust in technologies used in their care

PubMed Central

Montague, Enid

2011-01-01

In order to design effective health technologies and systems, it is important to understand how patients learn and make decisions about health technologies used in their care. The objective of this study was to examine patients' source of learning about technologies used in their care and how the source related to their trust in the technology used. Individual face-to-face and telephone interviews were conducted with 24 patients. Thirteen unique sources of information about technology were identified and three major themes emerged; outside of the work system versus inside the work system, when the health information was provided, and the medium used. Patients used multiple sources outside of the health care work system to learn about technologies that will be used in their care. Results showed a relationship between learning about technologies from web sources and trust in technologies but no relationship between learning about technologies from health care providers and trust in technologies. PMID:20967654

How different types of users develop trust in technology: A qualitative analysis of the antecedents of active and passive user trust in a shared technology

PubMed Central

Xu, Jie; Le, Kim; Deitermann, Annika; Montague, Enid

2014-01-01

The aim of this study was to investigate the antecedents of trust in technology for active users and passive users working with a shared technology. According to the prominence-interpretation theory, to assess the trustworthiness of a technology, a person must first perceive and evaluate elements of the system that includes the technology. An experimental study was conducted with 54 participants who worked in two-person teams in a multi-task environment with a shared technology. Trust in technology was measured using a trust in technology questionnaire and antecedents of trust were elicited using an open-ended question. A list of antecedents of trust in technology was derived using qualitative analysis techniques. The following categories emerged from the antecedent: technology factors, user factors, and task factors. Similarities and differences between active users and passive user responses, in terms of trust in technology were discussed. PMID:24882059

How different types of users develop trust in technology: a qualitative analysis of the antecedents of active and passive user trust in a shared technology.

PubMed

Xu, Jie; Le, Kim; Deitermann, Annika; Montague, Enid

2014-11-01

The aim of this study was to investigate the antecedents of trust in technology for active users and passive users working with a shared technology. According to the prominence-interpretation theory, to assess the trustworthiness of a technology, a person must first perceive and evaluate elements of the system that includes the technology. An experimental study was conducted with 54 participants who worked in two-person teams in a multi-task environment with a shared technology. Trust in technology was measured using a trust in technology questionnaire and antecedents of trust were elicited using an open-ended question. A list of antecedents of trust in technology was derived using qualitative analysis techniques. The following categories emerged from the antecedent: technology factors, user factors, and task factors. Similarities and differences between active users and passive user responses, in terms of trust in technology were discussed. Copyright © 2014 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Protecting Defense Technologies: DOD Assessment Needed to Determine Requirement for Critical Technologies List

DTIC Science & Technology

2013-01-01

Service DTSA Defense Technology Security Administration MCTL Militarily Critical Technologies List This is a work of the U.S. government and is not...Respond to MCTL Weaknesses Page 8 GAO-13-157 Protecting Defense Technologies Administration ( DTSA ), military services, and DOD...implementation of technology security policies on international transfers of defense- related goods, services, and technologies; • directed DTSA to

Technology Transfer Report

NASA Technical Reports Server (NTRS)

2000-01-01

Since its inception, Goddard has pursued a commitment to technology transfer and commercialization. For every space technology developed, Goddard strives to identify secondary applications. Goddard then provides the technologies, as well as NASA expertise and facilities, to U.S. companies, universities, and government agencies. These efforts are based in Goddard's Technology Commercialization Office. This report presents new technologies, commercialization success stories, and other Technology Commercialization Office activities in 1999.

Quantifying Adoption Rates and Energy Savings Over Time for Advanced Manufacturing Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hanes, Rebecca; Carpenter Petri, Alberta C; Riddle, Matt

Energy-efficient manufacturing technologies can reduce energy consumption and lower operating costs for an individual manufacturing facility, but increased process complexity and the resulting risk of disruption means that manufacturers may be reluctant to adopt such technologies. In order to quantify potential energy savings at scales larger than a single facility, it is necessary to account for how quickly and how widely the technology will be adopted by manufacturers. This work develops a methodology for estimating energy-efficient manufacturing technology adoption rates using quantitative, objectively measurable technology characteristics, including energetic, economic and technical criteria. Twelve technology characteristics are considered, and each characteristicmore » is assigned an importance weight that reflects its impact on the overall technology adoption rate. Technology characteristic data and importance weights are used to calculate the adoption score, a number between 0 and 1 that represents how quickly the technology is likely to be adopted. The adoption score is then used to estimate parameters for the Bass diffusion curve, which quantifies the change in the number of new technology adopters in a population over time. Finally, energy savings at the sector level are calculated over time by multiplying the number of new technology adopters at each time step with the technology's facility-level energy savings. The proposed methodology will be applied to five state-of-the-art energy-efficient technologies in the carbon fiber composites sector, with technology data obtained from the Department of Energy's 2016 bandwidth study. Because the importance weights used in estimating the Bass curve parameters are subjective, a sensitivity analysis will be performed on the weights to obtain a range of parameters for each technology. The potential energy savings for each technology and the rate at which each technology is adopted in the sector are quantified and used to identify the technologies which offer the greatest cumulative sector-level energy savings over a period of 20 years. Preliminary analysis indicates that relatively simple technologies, such as efficient furnaces, will be adopted more quickly and result in greater cumulative energy savings compared to more complex technologies that require process retrofitting, such as advanced control systems.« less

Innovative Technologies for Global Space Exploration

NASA Technical Reports Server (NTRS)

Hay, Jason; Gresham, Elaine; Mullins, Carie; Graham, Rachael; Williams-Byrd; Reeves, John D.

2012-01-01

Under the direction of NASA's Exploration Systems Mission Directorate (ESMD), Directorate Integration Office (DIO), The Tauri Group with NASA's Technology Assessment and Integration Team (TAIT) completed several studies and white papers that identify novel technologies for human exploration. These studies provide technical inputs to space exploration roadmaps, identify potential organizations for exploration partnerships, and detail crosscutting technologies that may meet some of NASA's critical needs. These studies are supported by a relational database of more than 400 externally funded technologies relevant to current exploration challenges. The identified technologies can be integrated into existing and developing roadmaps to leverage external resources, thereby reducing the cost of space exploration. This approach to identifying potential spin-in technologies and partnerships could apply to other national space programs, as well as international and multi-government activities. This paper highlights innovative technologies and potential partnerships from economic sectors that historically are less connected to space exploration. It includes breakthrough concepts that could have a significant impact on space exploration and discusses the role of breakthrough concepts in technology planning. Technologies and partnerships are from NASA's Technology Horizons and Technology Frontiers game-changing and breakthrough technology reports as well as the External Government Technology Dataset, briefly described in the paper. The paper highlights example novel technologies that could be spun-in from government and commercial sources, including virtual worlds, synthetic biology, and human augmentation. It will consider how these technologies can impact space exploration and will discuss ongoing activities for planning and preparing them.

Decision Gate Process for Assessment of a Technology Development Portfolio

NASA Technical Reports Server (NTRS)

Kohli, Rajiv; Fishman, Julianna; Hyatt, Mark

2012-01-01

The NASA Dust Management Project (DMP) was established to provide technologies (to TRL 6 development level) required to address adverse effects of lunar dust to humans and to exploration systems and equipment, which will reduce life cycle cost and risk, and will increase the probability of sustainable and successful lunar missions. The technology portfolio of DMP consisted of different categories of technologies whose final product is either a technology solution in itself, or one that contributes toward a dust mitigation strategy for a particular application. A Decision Gate Process (DGP) was developed to assess and validate the achievement and priority of the dust mitigation technologies as the technologies progress through the development cycle. The DGP was part of continuous technology assessment and was a critical element of DMP risk management. At the core of the process were technology-specific criteria developed to measure the success of each DMP technology in attaining the technology readiness levels assigned to each decision gate. The DGP accounts for both categories of technologies and qualifies the technology progression from technology development tasks to application areas. The process provided opportunities to validate performance, as well as to identify non-performance in time to adjust resources and direction. This paper describes the overall philosophy of the DGP and the methodology for implementation for DMP, and describes the method for defining the technology evaluation criteria. The process is illustrated by example of an application to a specific DMP technology.

Technology Games: Using Wittgenstein for Understanding and Evaluating Technology.

PubMed

Coeckelbergh, Mark

2017-08-15

In the philosophy of technology after the empirical turn, little attention has been paid to language and its relation to technology. In this programmatic and explorative paper, it is proposed to use the later Wittgenstein, not only to pay more attention to language use in philosophy of technology, but also to rethink technology itself-at least technology in its aspect of tool, technology-in-use. This is done by outlining a working account of Wittgenstein's view of language (as articulated mainly in the Investigations) and by then applying that account to technology-turning around Wittgenstein's metaphor of the toolbox. Using Wittgenstein's concepts of language games and form of life and coining the term 'technology games', the paper proposes and argues for a use-oriented, holistic, transcendental, social, and historical approach to technology which is empirically but also normatively sensitive, and which takes into account implicit knowledge and know-how. It gives examples of interaction with social robots to support the relevance of this project for understanding and evaluating today's technologies, makes comparisons with authors in philosophy of technology such as Winner and Ihde, and sketches the contours of a phenomenology and hermeneutics of technology use that may help us to understand but also to gain a more critical relation to specific uses of concrete technologies in everyday contexts. Ultimately, given the holism argued for, it also promises a more critical relation to the games and forms of life technologies are embedded in-to the ways we do things.

Advanced Technology Lifecycle Analysis System (ATLAS) Technology Tool Box (TTB)

NASA Technical Reports Server (NTRS)

Doyle, Monica; ONeil, Daniel A.; Christensen, Carissa B.

2005-01-01

The Advanced Technology Lifecycle Analysis System (ATLAS) is a decision support tool designed to aid program managers and strategic planners in determining how to invest technology research and development dollars. It is an Excel-based modeling package that allows a user to build complex space architectures and evaluate the impact of various technology choices. ATLAS contains system models, cost and operations models, a campaign timeline and a centralized technology database. Technology data for all system models is drawn from a common database, the ATLAS Technology Tool Box (TTB). The TTB provides a comprehensive, architecture-independent technology database that is keyed to current and future timeframes.

Technology Assessment Need: Review on Attractiveness and Competitiveness

NASA Astrophysics Data System (ADS)

Salwa Sait, Siti; Merlinda Muharam, Farrah; Chin, Thoo Ai; Sulaiman, Zuraidah

2017-06-01

Technology assessment is crucial in managing technology for the purpose of technology exploitation. With business environment continuously changing, firms have to address this issue critically as technology is considered one of the important elements to evaluate performance and gain competitive advantage. Missteps in deciding the best technology to be developed, employed or maintained would cost the firm overall value. To fulfil the need of finding the appropriate scale to assess suitable technology, this paper summarizes that technology assessment (TA) should cover two main aspects, namely technology attractiveness and competitiveness. These components are seen capable to link the scale suggested towards evaluation of financial and non-financial performance towards competitive advantage.

FCS Technology Investigation Overview

NASA Technical Reports Server (NTRS)

Budinger, James; Gilbert, Tricia

2007-01-01

This working paper provides an overview of the Future Communication Study (FCS) technology investigation progress. It includes a description of the methodology applied to technology evaluation; evaluation criteria; and technology screening (down select) results. A comparison of screening results with other similar technology screening activities is provided. Additional information included in this working paper is a description of in-depth studies (including characterization of the L-band aeronautical channel; L-band deployment cost assessment; and performance assessments of candidate technologies in the applicable aeronautical channel) that have been conducted to support technology evaluations. The paper concludes with a description on-going activities leading to conclusion of the technology investigation and the development of technology recommendations.

The Struggle for Technology: Towards a Realistic Political Theory of Technology.

PubMed

Verbeek, Peter-Paul

2017-01-01

Pieter Lemmens' neo-Marxist approach to technology urges us to rethink how to do political philosophy of technology. First, Lemmens' high level of abstraction raises the question of how empirically informed a political theory of technology needs to be. Second, his dialectical focus on a "struggle" between humans and technologies reveals the limits of neo-Marxism. Political philosophy of technology needs to return "to the things themselves". The political significance of technologies cannot be reduced to its origins in systems of production or social organization, but requires study at the micro-level, where technologies help to shape engagement, interaction, power, and social awareness.

Method for technology-delivered healthcare measures.

PubMed

Kramer-Jackman, Kelli Lee; Popkess-Vawter, Sue

2011-12-01

Current healthcare literature lacks development and evaluation methods for research and practice measures administered by technology. Researchers with varying levels of informatics experience are developing technology-delivered measures because of the numerous advantages they offer. Hasty development of technology-delivered measures can present issues that negatively influence administration and psychometric properties. The Method for Technology-delivered Healthcare Measures is designed to systematically guide the development and evaluation of technology-delivered measures. The five-step Method for Technology-delivered Healthcare Measures includes establishment of content, e-Health literacy, technology delivery, expert usability, and participant usability. Background information and Method for Technology-delivered Healthcare Measures steps are detailed.

Software Engineering Research/Developer Collaborations in 2005

NASA Technical Reports Server (NTRS)

Pressburger, Tom

2006-01-01

In CY 2005, three collaborations between software engineering technology providers and NASA software development personnel deployed three software engineering technologies on NASA development projects (a different technology on each project). The main purposes were to benefit the projects, infuse the technologies if beneficial into NASA, and give feedback to the technology providers to improve the technologies. Each collaboration project produced a final report. Section 2 of this report summarizes each project, drawing from the final reports and communications with the software developers and technology providers. Section 3 indicates paths to further infusion of the technologies into NASA practice. Section 4 summarizes some technology transfer lessons learned. Also included is an acronym list.

Technological Innovation of Thin-Film Transistors: Technology Development, History, and Future

NASA Astrophysics Data System (ADS)

Yamamoto, Yoshitaka

2012-06-01

The scale of the liquid crystal display industry has expanded rapidly, driven by technological innovations for thin-film transistors (TFTs). The TFT technology, which started from amorphous silicon (a-Si), has produced large TVs, and low-temperature polycrystalline silicon (poly-Si) has become a core technology for small displays, such as mobile phones. Recently, various TFT technological seeds have been realized, indicating that new information appliances that match new lifestyles and information infrastructures will be available in the near future. In this article, I review the history of TFT technology and discuss the future of TFT technological development from the technological innovation viewpoint.

Users speak out on technology deployment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peters, Mark; Prochaska, Marty; Cromer, Paul

2001-02-25

This report summarizes user feedback data collected during a recent Accelerated Site Technology Deployment (ASTD) project: the Fluor Fernald ASTD Technology Deployment Project from May, 1999 through September, 2000. The main goal of the ASTD project was to use the ''Fernald approach'' to expedite the deployment of new or innovative technologies with superior safety, cost, and/or productivity benefits to Department of Energy (DOE) facilities. The Fernald approach targets technology end-users and their managers and directly involves them with hands-on demonstrations of new or innovative technologies during technology transfer sessions. The two technologies deployed through this project were the Personal Icemore » Cooling System (PICS) and the oxy-gasoline torch. Participants of technology transfer sessions were requested to complete feedback surveys. Surveys evaluated the effectiveness of the Fernald approach to technology deployment and assessed the responsiveness of employees to new technologies. This report presents the results of those surveys.« less

Technology Area Roadmap for In Space Propulsion Technologies

NASA Technical Reports Server (NTRS)

Johnson, Les; Meyer, Mike; Coote, David; Goebel, Dan; Palaszewski, Bryan; White, Sonny

2010-01-01

This slide presentation reviews the technology area (TA) roadmap to develop propulsion technologies that will be used to enable further exploration of the solar system, and beyond. It is hoped that development of the technologies within this TA will result in technical solutions that will improve thrust levels, specific impulse, power, specific mass, volume, system mass, system complexity, operational complexity, commonality with other spacecraft systems, manufacturability and durability. Some of the propulsion technologies that are reviewed include: chemical and non-chemical propulsion, and advanced propulsion (i.e., those with a Technology Readiness level of less than 3). Examples of these advanced technologies include: Beamed Energy, Electric Sail, Fusion, High Energy Density Materials, Antimatter, Advanced Fission and Breakthrough propulsion technologies. Timeframes for development of some of these propulsion technologies are reviewed, and top technical challenges are reviewed. This roadmap describes a portfolio of in-space propulsion technologies that can meet future space science and exploration needs.

Middle school special education teachers' perceptions and use of assistive technology in literacy instruction.

PubMed

Flanagan, Sara; Bouck, Emily C; Richardson, Jennifer

2013-01-01

In this research the authors examined middle school special education teachers' perceptions of assistive technology during literacy instruction with students with high incidence disabilities. A survey explored the use, effectiveness, and factors impacting use or effectiveness of assistive technology for literacy teaching and learning. Results suggested teachers' perceived assistive technology to be an effective tool for literacy, but use it minimally. When assistive technology was used, teachers indicated it was an effective literacy support. Teachers also reported barriers to using assistive technology in literacy including cost, usability, and lack of training/experience. However, factors such as previous successful experiences with assistive technology and assistive technology supporting students' learning encouraged assistive technology use. The consistency of teachers' reports of needing more experience and knowledge in assistive technology to fully use it suggests implications for preservice preparation such as providing additional experiences and information on assistive technology.

Understanding Active and Passive Users: The Effects of an Active User Using Normal, Hard and Unreliable Technologies on User Assessment of Trust in Technology and Co-User

PubMed Central

Montague, Enid; JieXu

2011-01-01

The aim of this study was to understand how passive users perceive the trustworthiness of active users and technologies under varying technological conditions. An experimental study was designed to vary the functioning of technologies that active users interacted with, while passive users observed these interactions. Active and passive user ratings of technology and partner were collected. Exploratory data analysis suggests that passive users developed perceptions of technologies based on the functioning of the technology and how the active user interacted with the technologies. Findings from this research have implications for the design of technologies in environments where active and passive users interact with technologies in different ways. Future work in this area should explore interventions that lead to enhanced affective engagement and trust calibration. PMID:22192788

Issues of doing gender and doing technology - Music as an innovative theme for technology education

NASA Astrophysics Data System (ADS)

Thaler, A.; Zorn, I.

2010-08-01

This paper presents the concept and results of the research project 'Engineer Your Sound!' (2008-2009). It aimed at exploring whether interdisciplinary, innovative teaching/learning settings in the fields of technology and digital media can be used to give pupils the opportunities to experiment and discover their technical potential, skills, interests and talents and if music technology could offer such an appealing context. The paper explains how technology and why gender need to be addressed when planning to raise young people's interest in technology but questions if interest in technology is mainly influenced by gender. The paper explores through ethnographic research how pupils' technological competencies and interests have developed during the course of a technology-related project. Results of the analysis explain how music technology can serve as a suitable theme with the potential to increase both males' and females' interest in technology.

Incorporating Experimental Technologies in the Middle Level Technology Education Classroom

ERIC Educational Resources Information Center

Shields, C. J.; Rogers, George E.

2005-01-01

This paper offers some concrete ideas and suggestions for incorporating discussions of experimental technologies in the middle level technology education classroom. Technology education students should be aware of experimental technologies. They should understand the ramifications of items such as hybrid vehicles, photovoltaic solar panels,…

75 FR 3203 - National Medal of Technology and Innovation Call for 2010 Nominations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-20

... outstanding, lasting contribution to the economy through the promotion of technology or technological manpower... contributions to the promotion of technology or technological manpower for the improvement of the economic... highlights the national importance of fostering technological innovation based upon solid science, resulting...

75 FR 82378 - National Medal of Technology and Innovation Call for 2011 Nominations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-30

... the promotion of technology or technological manpower, you may obtain a nomination form from: http... promotion of technology and technological manpower for the improvement of the economic, environmental or... national importance of fostering technological innovation based upon solid science, resulting in...

How Technology Teachers Understand Technological Knowledge

ERIC Educational Resources Information Center

Norström, Per

2014-01-01

Swedish technology teachers' views of technological knowledge are examined through a written survey and a series of interviews. The study indicates that technology teachers' understandings of what constitutes technological knowledge and how it is justified vary considerably. The philosophical discussions on the topic are unknown to them. This lack…

Gauging Technology Costs and Benefits

ERIC Educational Resources Information Center

Kaestner, Rich

2007-01-01

Regardless of the role technology plays in a school district, district personnel should know the costs associated with technology, understand the consequences of technology purchases, and be able to measure the benefits of technology, so they can make more informed decisions. However, determining costs and benefits of current technology or…

The Dairy Technology System in Venezuela. Summary of Research 79.

ERIC Educational Resources Information Center

Nieto, Ruben D.; Henderson, Janet L.

A study examined the agricultural technology system in Venezuela with emphasis on the dairy industry. An analytical framework was used to identify the strengths and weaknesses of the following components of Venezuela's agricultural technology system: policy, technology development, technology transfer, and technology use. Selected government…

Policy formulation and technology assessment.

PubMed

Banta, H D; Behney, C J

1981-01-01

Describes technology assessment and its application to the health field; examines evaluation of efficacy, safety, and cost effectiveness; discusses the use of technology assessment in policy formulation, especially by federal programs; suggests a system for assessment of medical technologies; and offers some observations about the future of technology assessment in policy making. Technology assessment began formally in 1965 in the Committee on Science and Astronautics of the House of Representatives as a process of examining technology and its impacts. Only a few attempts have been made since then to apply the concepts of technology assessment to health care. The amount of money currently devoted to assessing the efficacy and safety of medical technologies is small, and many important technologies have not been assessed. Priorities for clinical trials should therefore be set. Cost effectiveness analysis is a useful tool in decision making but because of its inherent limitations, it should not be the sole or even primary determinant of a decision. Technology assessment is apparently infrequently used as a decision-assisting tool by 3rd party payers, federal government agencies funding biomedical research, or the federal program which is designed to control physician utilization of certain technologies. Only the FDA regularly utilizes technology assessment. A systematic program of technology assessment would require identification of technologies needing testing, setting of priorities for such tests, synthesizing of information gained and its dessemination to decision makers.

Trust in technology-mediated collaborative health encounters: constructing trust in passive user interactions with technologies.

PubMed

Montague, Enid; Asan, Onur

2012-01-01

The present study investigated factors that explain patient trust in health technology and the relationship between patient trust in technology and trust in their care provider. Sociotechnical systems theory states that changes in one part of the system are likely related to other parts of the system. Therefore, attitudes about technologies, like trust, are likely related to other aspects of the system. Contributing to appropriate trust at the technological, interpersonal, and system levels can potentially lead to positive health outcomes. The study described in this manuscript used data collected from 101 patients with a Trust in Medical Technology instrument. The instrument measured patients' trust in (1) their providers, (2) the technology, and (3) how their providers used the technology. Measure 3 was positively associated with measures 1 and 2, while measures 1 and 2 were not positively or negatively associated with one another. These results may indicate that patient assessments of the trustworthiness of care providers and technologies are based on their observations of how providers use technologies. Though patients are not active users of technologies in health care, the results of this study show that their perceptions of how providers use technology are related to their trust in both technology and the care provider. Study findings have implications for how trust is conceptualised and measured in interpersonal relationships and in technologies.

Toward equality of biodiversity knowledge through technology transfer.

PubMed

Böhm, Monika; Collen, Ben

2015-10-01

To help stem the continuing decline of biodiversity, effective transfer of technology from resource-rich to biodiversity-rich countries is required. Biodiversity technology as defined by the Convention on Biological Diversity (CBD) is a complex term, encompassing a wide variety of activities and interest groups. As yet, there is no robust framework by which to monitor the extent to which technology transfer might benefit biodiversity. We devised a definition of biodiversity technology and a framework for the monitoring of technology transfer between CBD signatories. Biodiversity technology within the scope of the CBD encompasses hard and soft technologies that are relevant to the conservation and sustainable use of biodiversity, or make use of genetic resources, and that relate to all aspects of the CBD, with a particular focus on technology transfer from resource-rich to biodiversity-rich countries. Our proposed framework introduces technology transfer as a response indicator: technology transfer is increased to stem pressures on biodiversity. We suggest an initial approach of tracking technology flow between countries; charting this flow is likely to be a one-to-many relationship (i.e., the flow of a specific technology from one country to multiple countries). Future developments should then focus on integrating biodiversity technology transfer into the current pressure-state-response indicator framework favored by the CBD (i.e., measuring the influence of technology transfer on changes in state and pressure variables). Structured national reporting is important to obtaining metrics relevant to technology and knowledge transfer. Interim measures, that can be used to assess biodiversity technology or knowledge status while more in-depth indicators are being developed, include the number of species inventories, threatened species lists, or national red lists; databases on publications and project funding may provide measures of international cooperation. Such a pragmatic approach, followed by rigorous testing of specific technology transfer metrics submitted by CBD signatories in a standardized manner may in turn improve the focus of future targets on technology transfer for biodiversity conservation. © 2015 Society for Conservation Biology.

NASA In-Space Propulsion Technologies and Their Infusion Potential

NASA Technical Reports Server (NTRS)

Anderson, David J.; Pencil,Eric J.; Peterson, Todd; Vento, Daniel; Munk, Michelle M.; Glaab, Louis J.; Dankanich, John W.

2012-01-01

The In-Space Propulsion Technology (ISPT) program has been developing in-space propulsion technologies that will enable or enhance NASA robotic science missions. The ISPT program is currently developing technology in four areas that include Propulsion System Technologies (Electric and Chemical), Entry Vehicle Technologies (Aerocapture and Earth entry vehicles), Spacecraft Bus and Sample Return Propulsion Technologies (components and ascent vehicles), and Systems/Mission Analysis. Three technologies are ready for flight infusion: 1) the high-temperature Advanced Material Bipropellant Rocket (AMBR) engine providing higher performance; 2) NASA s Evolutionary Xenon Thruster (NEXT) ion propulsion system, a 0.6-7 kW throttle-able gridded ion system; and 3) Aerocapture technology development with investments in a family of thermal protection system (TPS) materials and structures; guidance, navigation, and control (GN&C) models of blunt-body rigid aeroshells; and aerothermal effect models. Two component technologies that will be ready for flight infusion in the near future will be Advanced Xenon Flow Control System, and ultra-lightweight propellant tank technologies. Future focuses for ISPT are sample return missions and other spacecraft bus technologies like: 1) Mars Ascent Vehicles (MAV); 2) multi-mission technologies for Earth Entry Vehicles (MMEEV) for sample return missions; and 3) electric propulsion for sample return and low cost missions. These technologies are more vehicle-focused, and present a different set of technology infusion challenges. While the Systems/Mission Analysis area is focused on developing tools and assessing the application of propulsion technologies to a wide variety of mission concepts. These in-space propulsion technologies are applicable, and potentially enabling for future NASA Discovery, New Frontiers, and sample return missions currently under consideration, as well as having broad applicability to potential Flagship missions. This paper provides a brief overview of the ISPT program, describing the development status and technology infusion readiness of in-space propulsion technologies in the areas of electric propulsion, aerocapture, Earth entry vehicles, propulsion components, Mars ascent vehicle, and mission/systems analysis.

NASA space research and technology overview (ITP)

NASA Technical Reports Server (NTRS)

Reck, Gregory M.

1992-01-01

A series of viewgraphs summarizing NASA space research and technology is presented. Some of the specific topics covered include the organization and goals of the Office of Aeronautics and Space Technology, technology maturation strategy, integrated technology plan for the Civil Space Program, program selection and investment prioritization, and space technology benefits.

A Path Model of Factors Affecting Secondary School Students' Technological Literacy

ERIC Educational Resources Information Center

Avsec, Stanislav; Jamšek, Janez

2018-01-01

Technological literacy defines a competitive vision for technology education. Working together with competitive supremacy, technological literacy shapes the actions of technology educators. Rationalised by the dictates of industry, technological literacy was constructed as a product of the marketplace. There are many models that visualise…

Electro-Technologies. Guide to Standards and Implementation. Career & Technology Studies.

ERIC Educational Resources Information Center

Alberta Dept. of Education, Edmonton. Curriculum Standards Branch.

With this Career and Technologies Studies (CTS) curriculum guide, secondary students in Alberta can do the following: develop skills that can be applied in their daily lives; refine career-planning skills; develop technology-related skills in electro-technologies; enhance employability skills, especially in electro-technologies industries; and…

U.S. Military Technology Dependence: The Hidden Vulnerability to National Security

DTIC Science & Technology

2016-06-10

complementary technologies among the services, decreasing the innovation to fielding timeline, and practice in degraded technology environments. 15. SUBJECT TERMS...technologies among the services, decreasing the innovation to fielding timeline, and practice in degraded technology environments. vi...29 SECTION 4: Fielding New Technology ................................................................... 32 Understanding the

Teachers' Perceptions of the Dimensions and Implementation of Technology Leadership of Principals in Taiwanese Elementary Schools

ERIC Educational Resources Information Center

Chang, I-Hua; Chin, Joseph M.; Hsu, Cheng-Mei

2008-01-01

Principals' technology leadership is strongly correlated with teachers' integration of educational technology, and technology leadership is necessary for effective utilization of technology in schooling. The article describes a study that empirically investigated teachers' perceptions of elementary schools principals' technology leadership…

Children's Developing Understanding of Technology

ERIC Educational Resources Information Center

Mawson, Brent

2010-01-01

The issue of children's conceptions of technology and technology education is seen as important by technology educators. While there is a solid body of literature that documents groups of children's understandings of technology and technology education, this is primarily focused on snapshot studies of children aged 11 and above. There is little…

SITE TECHNOLOGY CAPSULE; MULTI-VENDOR BIOREMEDIATION DEMONSTRATION PROJECT: ENVIRONMENTAL LABORATORIES/SBP TECHNOLOGIES' UVB VACUUM VAPORIZATION WELL PROCESS

EPA Science Inventory

This technology capsule summarizes the findings of an evaluation of the Unterdruck-Verdampfer-Brunnen (UVB) technology developed by IEG Technologies (IEG) and licensed in the eastern United States by Environmental Laboratories, Inc. (ELI) and SBP Technologies, Inc. (SBP). This e...

Mississippi Curriculum Framework for Technology Discovery (9th Grade). CIP: 00.0253.

ERIC Educational Resources Information Center

Mississippi Research and Curriculum Unit for Vocational and Technical Education, State College.

This document, which is intended for technology educators in Mississippi, outlines a technology discovery course in which a modular instruction approach allows ninth graders to experience various workplace technologies within four career cluster areas: agriculture/natural resources technology, business/marketing technology, health/human services…

New Jersey State Library Technology Plan, 1999-2001.

ERIC Educational Resources Information Center

Breedlove, Elizabeth A., Ed.

This document represents the New Jersey State Library Technology Plan for 1999-2001. Contents include: the mission statement; technology planning process of the Technology Committee (convened by the State Library); specific goals of the Technology Plan 1999-2001; technology assumptions for the operational library and statewide library services;…

45 CFR 170.553 - Certification of health information technology other than Complete EHRs and EHR Modules.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 1 2011-10-01 2011-10-01 false Certification of health information technology... AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS... TECHNOLOGY Permanent Certification Program for HIT § 170.553 Certification of health information technology...

45 CFR 170.553 - Certification of health information technology other than Complete EHRs and EHR Modules.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 1 2014-10-01 2014-10-01 false Certification of health information technology... and Human Services HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS... TECHNOLOGY ONC HIT Certification Program § 170.553 Certification of health information technology other than...

45 CFR 170.553 - Certification of health information technology other than Complete EHRs and EHR Modules.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 1 2012-10-01 2012-10-01 false Certification of health information technology... AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS... TECHNOLOGY Permanent Certification Program for HIT § 170.553 Certification of health information technology...

45 CFR 170.553 - Certification of health information technology other than Complete EHRs and EHR Modules.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 1 2013-10-01 2013-10-01 false Certification of health information technology... AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS... TECHNOLOGY ONC HIT Certification Program § 170.553 Certification of health information technology other than...

Space teleoperations technology for Space Station evolution

NASA Technical Reports Server (NTRS)

Reuter, Gerald J.

1990-01-01

Viewgraphs on space teleoperations technology for space station evolution are presented. Topics covered include: shuttle remote manipulator system; mobile servicing center functions; mobile servicing center technology; flight telerobotic servicer-telerobot; flight telerobotic servicer technology; technologies required for space station assembly; teleoperation applications; and technology needs for space station evolution.

State of the art survey of technologies applicable to NASA's aeronautics, avionics and controls program

NASA Technical Reports Server (NTRS)

Smyth, R. K. (Editor)

1979-01-01

The state of the art survey (SOAS) covers six technology areas including flightpath management, aircraft control system, crew station technology, interface & integration technology, military technology, and fundamental technology. The SOAS included contributions from over 70 individuals in industry, government, and the universities.

77 FR 2047 - National Medal of Technology and Innovation Call for 2012 Nominations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-13

... through the promotion of technology or technological manpower, you may obtain a nomination form from: http... to the promotion of technology and technological manpower for the improvement of the economic... highlights the national importance of fostering technological innovation based upon solid science, resulting...

Perceptions and Practice: The Relationship between Teacher Perceptions of Technology Use and Level of Classroom Technology Integration

ERIC Educational Resources Information Center

Sawyer, Laura M.

2017-01-01

This correlational-predictive study investigated the relationship between teacher perceptions of technology use and observed classroom technology integration level using the "Technology Uses and Perceptions Survey" (TUPS) and the "Technology Integration Matrix-Observation" (TIM-O) instruments, developed by the Florida Center…

Changing Technology and Work: Northern Telecom. CAW Technology Project.

ERIC Educational Resources Information Center

Robertson, David; Wareham, Jeff

A project to examine the implications of technological change at Northern Telecom consisted of two major components: a technological survey and case study research. A questionnaire that contained more than 90 questions on technological change was distributed through local union technology committee meetings in Brampton, London, Belleville, and…

75 FR 47317 - President's Council of Advisors on Science and Technology

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-05

... OFFICE OF SCIENCE AND TECHNOLOGY POLICY President's Council of Advisors on Science and Technology... Office of Science and Technology Policy (OSTP). PCAST is co-chaired by Dr. John P. Holdren, Assistant to the President for Science and Technology, and Director, Office of Science and Technology Policy...

Examples of the Integration of Technology in the Classroom.

ERIC Educational Resources Information Center

Kealey, Robert J., Ed.

This book presents the following case studies of how some Catholic schools have integrated technology: (1) "A Plan for the Integration of Technology" (Teresa Anthony); (2) "Integrating Technology in the Classroom" (Charlotte Bennett); (3) "From Commodore 64 to the Millennium Technology" (Ann Heidkamp); (4) "A Technology Project for the Eighth…

What Is Technology Education? A Review of the "Official Curriculum"

ERIC Educational Resources Information Center

Brown, Ryan A.; Brown, Joshua W.

2010-01-01

Technology education, not to be confused with educational technology, has an "official curriculum." This article explores this "official curriculum" and answers the following questions; what are the goals of technology education, what should technology education look like in classrooms, and why technology education is important. This article…

Technology Transfer Issues and a New Technology Transfer Model

ERIC Educational Resources Information Center

Choi, Hee Jun

2009-01-01

The following are major issues that should be considered for efficient and effective technology transfer: conceptions of technology, technological activity and transfer, communication channels, factors affecting transfer, and models of transfer. In particular, a well-developed model of technology transfer could be used as a framework for…

Barriers to Technology Use in Large and Small School Districts

ERIC Educational Resources Information Center

Francom, Gregory M.

2016-01-01

Barriers to effective technology integration come in several different categories, including access to technology tools and resources, technology training and support, administrative support, time to plan and prepare for technology integration, and beliefs about the importance and usefulness of technology tools and resources. This study used…

Philosophy of Technology Assumptions in Educational Technology Leadership

ERIC Educational Resources Information Center

Webster, Mark David

2017-01-01

A qualitative study using grounded theory methods was conducted to (a) examine what philosophy of technology assumptions are present in the thinking of K-12 technology leaders, (b) investigate how the assumptions may influence technology decision making, and (c) explore whether technological determinist assumptions are present. Subjects involved…

Preservice Teachers' Intention to Adopt Technology in Their Future Classrooms

ERIC Educational Resources Information Center

Li, Kun; Li, Yanju; Franklin, Teresa

2016-01-01

This study examined four factors that influence preservice teachers' intentions to adopt technology in classrooms based on the Theory of Planned Behavior and Technology Acceptance Model. These four factors--technology self-efficacy, attitudes toward technology, perceived ease of use of technology, and perceived barriers of technology…

Translation Technologies: A Dilemma between Translation Industry and Academia

ERIC Educational Resources Information Center

Bakul, Halil Ibrahim

2016-01-01

Today, physical and virtual borders are shrinking thanks to technology whose footprints are greater and faster than one can imagine. Beyond the shadow of a doubt, technology is associated with the areas for which it offers solutions such as education technologies, health technologies and translation technologies. Nowadays using translation…

Technology in the Montessori Classroom: Teachers' Beliefs and Technology Use

ERIC Educational Resources Information Center

Jones, Sara J.

2017-01-01

As technology becomes ubiquitous in society, there is increasing momentum to incorporate it into education. Montessori education is not immune to this push for technology integration. This qualitative study investigates four Upper Elementary Montessori teachers' attitudes toward technology and technology integration in a public school setting.…

K-12 Technology Accessibility: The Message from State Governments

ERIC Educational Resources Information Center

Shaheen, Natalie L.; Lazar, Jonathan

2018-01-01

This study examined state education technology plans and technology accessibility statutes to attempt to answer the question--is K-12 instructional technology accessibility discussed in state-level technology accessibility statutes and education technology plans across the 50 United States? When a K-12 school district is planning the construction…

Fix It with TAPE: Repurposing Technology to Be Assistive Technology for Students with High-Incidence Disabilities

ERIC Educational Resources Information Center

Bouck, Emily C.; Shurr, Jordan C.; Tom, Kinsey; Jasper, Andrea D.; Bassette, Laura; Miller, Bridget; Flanagan, Sara M.

2012-01-01

This article discusses how practitioners can repurpose technology--common and socially desirable technology in particular--to be assistive technology for students with high-incidence disabilities. The authors provide a framework for practitioners to consider technology for repurposing: TAPE (Transportable, Available, Practical, Engaging) and…

National Responses to Technological Innovations in Weapon Systems, 1815 to the Present

DTIC Science & Technology

1986-01-07

CONTENTS Pane Preface Introduction 1 I. Technology of the Industrial Revolution 4 II. Innovative Technologies of the Early Twentieth Century 18 III...focuses on the period from 1815 to the present, from the beginning of the Industrial Revolution to the latest developments in military technology...TECHNOLOGY OF THE INDUSTRIAL REVOLUTION Technological innovation has influenced warfare since antiquity. But the development of new- technology and

Digital technologies in occupational therapy and physiotherapy undergraduate and postgraduate education: a scoping review protocol.

PubMed

Olivier, Benita; Verdonck, Michele; Casteleijn, Daleen

2017-11-01

How have digital technologies been used in occupational therapy and physiotherapy undergraduate and postgraduate education?Specifically, the objective of this scoping review is to present an overview of research on the use of digital technologies in terms of type of digital technology used, pedagogy associated with the use of digital technology, subject/topic/area of application, experiences/perception of digital technology used, outcomes of the digital technology used and challenges to the use of digital technologies in occupational therapy and physiotherapy undergraduate and postgraduate education.

Commercial space opportunities - Advanced concepts and technology overview

NASA Technical Reports Server (NTRS)

Reck, Gregory M.

1993-01-01

The paper discusses the status of current and future commercial space opportunities. The goal is to pioneer innovative, customer-focused space concepts and technologies, leveraged through industrial, academic, and government alliance, to ensure U.S. commercial competitiveness and preeminence in space. The strategy is to develop technologies which enable new products and processes, deploy existing technology into commercial and military products and processes, and integrate military and commercial research and production activities. Technology development areas include information infrastructure, electronics design and manufacture, health care technology, environment technology, and aeronautical technologies.

[Patented technology status quo and development trend for Chinese herbal medicines].

PubMed

Li, Chang; Huang, Luqi

2009-06-01

Patent technology is regarded as technological trends under the market economy condition. The case showed the information form patent literature can be widely used in technology or economy. In this study, we analyzed the patent technology status quo and development trend for Chinese herbal medicines based on China patent database. The patent technology status quo is divided from the technology of biotechnology, quality control, cultivation and herb processing on Chinese herbal medicines. Furthermore, some recommendations of technology development and advices on patent protection for Chinese herbal medicines were suggested.

Mississippi Curriculum Framework for Business and Office and Related Technology Cluster. Office Systems Technology (CIP: 52.0401--Administrative Assistant/Secretarial). Accounting Technology (CIP: 52.0302). Medical Office Technology (CIP: 52.0404--Medical Admin. Asst./Secretarial). Microcomputer Technology (CIP: 52.0490). Court Reporting Technology (CIP: 52.0405). Paralegal Technology (CIP: Paralegal/Legal Assistant).

ERIC Educational Resources Information Center

Mississippi Research and Curriculum Unit for Vocational and Technical Education, State College.

This document, which is intended for use by community and junior colleges throughout Mississippi, contains curriculum frameworks for four programs in the postsecondary-level business and office cluster (office systems, accounting, medical office, and microcomputer technologies) and two programs in the legal cluster (court reporting and paralegal…

Integrated technology wing design study

NASA Technical Reports Server (NTRS)

Hays, A. P.; Beck, W. E.; Morita, W. H.; Penrose, B. J.; Skarshaug, R. E.; Wainfan, B. S.

1984-01-01

The technology development costs and associated benefits in applying advanced technology associated with the design of a new wing for a new or derivative trijet with a capacity for 350 passengers and maximum range of 8519 km, entering service in 1990 were studied. The areas of technology are: (1) airfoil technology; (2) planform parameters; (3) high lift; (4) pitch active control system; (5) all electric systems; (6) E to 3rd power propulsion; (7) airframe/propulsion integration; (8) graphite/epoxy composites; (9) advanced aluminum alloys; (10) titanium alloys; and (11) silicon carbide/aluminum composites. These technologies were applied to the reference aircraft configuration. Payoffs were determined for block fuel reductions and net value of technology. These technologies are ranked for the ratio of net value of technology (NVT) to technology development costs.

Appropriate strategies.

PubMed

Halty, M

1979-01-01

Technology strategies are concerned with the production, distribution, and consumption of technology. Observation of less developed countries (LDCs) and international organizations shows that little attention is given to the development of a technology strategy. LDCs need to formulate a strategy of self-reliant technological development for the next decade. They should no longer be content to stand in a technologically dependent relationship to the developed countries. Such strategies must balance the ratio between investment in indigenous technologies and expenditure for foreign technology. The strategies change according to the level of industrialization achieved. The following considerations come into development of technology strategies: 1) determination of an appropriate balance among the accumulation, consumption, and distribution of technology; 2) the amount and level of government support; and 3) the balance between depth and breadth of technology to be encouraged.

Assistive technology and learning disabilities: today's realities and tomorrow's promises.

PubMed

Lewis, R B

1998-01-01

Many forms of technology, both "high" and "low," can help individuals with learning disabilities capitalize on their strengths and bypass, or compensate for, their disabilities. This article surveys the current status of assistive technology for this population and reflects on future promises and potential problems. In addition, a model is presented for conceptualizing assistive technology in terms of the types of barriers it helps persons with disabilities to surmount. Several current technologies are described and the research supporting their effectiveness reviewed: word processing, computer-based instruction in reading and other academic areas, interactive videodisc interventions for math, and technologies for daily life. In conclusion, three themes related to the future success of assistive technology applications are discussed: equity of access to technology; ease of technology, use; and emergent technologies, such as virtual reality.

[The Technology Acceptance Model and Its Application in a Telehealth Program for the Elderly With Chronic Illnesses].

PubMed

Chang, Chi-Ping

2015-06-01

Many technology developments hold the potential to improve the quality of life of people and make life easier and more comfortable. New technologies have been well accepted by most people. Information sharing in particular is a major catalyst of change in our current technology-based society. Technology has widely innovated life and drastically changed lifestyles. The Technology Acceptance Model (TAM), a model developed to address the rapid advances in computer technology, is used to explain and predict user acceptance of new information technology. In the past, businesses have used the TAM as an assessment tool to predict user acceptance when introducing new technology products. They have also used external factors in the model to influence user perceptions and beliefs and to ensure the successful spread of new technologies. Informatization plays a critical role in healthcare services. Due to the rapid aging of populations and upward trends in the incidence of chronic illness, requirements for long-term care have increased in both quality and quantity. Therefore, there has been an increased emphasis on integrating healthcare and information technology. However, most elderly are significantly less adept at technology use than the general population. Therefore, we reexamined the effect that the essential concepts in a TAM exerted on technology acceptance. In the present study, the technology acceptance experience with regard to telehealth of the elderly was used as an example to explain how the revised technology acceptance model (TAM 2) may be effectively applied to enhance the understanding of technology care among nurses. The results may serve as a reference for future research on healthcare-technology use in long-term care or in elderly populations.

Towards G2G: Systems of Technology Database Systems

NASA Technical Reports Server (NTRS)

Maluf, David A.; Bell, David

2005-01-01

We present an approach and methodology for developing Government-to-Government (G2G) Systems of Technology Database Systems. G2G will deliver technologies for distributed and remote integration of technology data for internal use in analysis and planning as well as for external communications. G2G enables NASA managers, engineers, operational teams and information systems to "compose" technology roadmaps and plans by selecting, combining, extending, specializing and modifying components of technology database systems. G2G will interoperate information and knowledge that is distributed across organizational entities involved that is ideal for NASA future Exploration Enterprise. Key contributions of the G2G system will include the creation of an integrated approach to sustain effective management of technology investments that supports the ability of various technology database systems to be independently managed. The integration technology will comply with emerging open standards. Applications can thus be customized for local needs while enabling an integrated management of technology approach that serves the global needs of NASA. The G2G capabilities will use NASA s breakthrough in database "composition" and integration technology, will use and advance emerging open standards, and will use commercial information technologies to enable effective System of Technology Database systems.

American export control, technology spillover and innovation of Chinese pharmaceutical Industry.

PubMed

Hui, Jiang

2017-05-01

This paper was aimed to analyze whether the U.S. strict export control to China affects the technological innovation of Chinese pharmaceutical industry. This paper selected the data of technological innovation and the expenditure of high and new technology adoption in China's pharmaceutical industry from 1995 to 2014, created panel regression model to study the impact of export controls on technology spillovers and the impact of technology spillovers on innovation capacity. The results show that US export control has a significant impact on technology spillovers, but foreign technology spillovers have no significant impact on the innovation of Chinese pharmaceutical industry. Although the US export control prevented foreign technology spillovers to China, but indirectly stimulated the domestic technology spillovers to pharmaceutical manufacturing industry in China. Statistical analysis show that the correlation coefficient between innovation capacity and expenditure for high technology adoption is not significant, but the expenditure of purchasing domestic technical is essential to pharmaceutical innovation. This study shows that US export control indirectly, not directly, affected the technological innovation of China's pharmaceutical industry, affected the allocation of innovative resources, but failed to prevent the technological progress and competitiveness improvement of Chinese pharmaceutical industry.

Technology Integration in a Science Classroom: Preservice Teachers' Perceptions

NASA Astrophysics Data System (ADS)

Rehmat, Abeera P.; Bailey, Janelle M.

2014-12-01

The challenge of preparing students for the information age has prompted administrators to increase technology in the public schools. Yet despite the increased availability of technology in schools, few teachers are integrating technology for instructional purposes. Preservice teachers must be equipped with adequate content knowledge of technology to create an advantageous learning experience in science classrooms. To understand preservice teachers' conceptions of technology integration, this research study explored 15 elementary science methods students' definitions of technology and their attitudes toward incorporating technology into their teaching. The phenomenological study took place in a science methods course that was based on a constructivist approach to teaching and learning science through science activities and class discussions, with an emphasis on a teacher beliefs framework. Data were collected throughout the semester, including an open-ended pre/post-technology integration survey, lesson plans, and reflections on activities conducted throughout the course. Through a qualitative analysis, we identified improvements in students' technology definitions, increased technology incorporation into science lesson plans, and favorable attitudes toward technology integration in science teaching after instruction. This research project demonstrates that positive changes in beliefs and behaviors relating to technology integration in science instruction among preservice teachers are possible through explicit instruction.

The investigation of science teachers’ experience in integrating digital technology into science teaching

NASA Astrophysics Data System (ADS)

Agustin, R. R.; Liliasari; Sinaga, P.; Rochintaniawati, D.

2018-05-01

The use of technology into science learning encounters problems. One of the problem is teachers’ less technological pedagogical and content knowledge (TPACK) on the implementation of technology itself. The purpose of this study was to investigate science teachers’ experience in using digital technology into science classroom. Through this study science teachers’ technological knowledge (TK) and technological content knowledge (TCK) can be unpacked. Descriptive method was used to depict science teachers’ TK and TCK through questionnaire that consisted of 20 questions. Subjects of this study were 25 science teachers in Bandung, Indonesia. The study was conducted in the context of teacher professional training. Result shows that science teachers still have less TK, yet they have high TCK. The teachers consider characteristics of concepts as main aspect for implementing technology into science teaching. This finding describes teachers’ high technological content knowledge. Meanwhile, science teachers’ technological knowledge was found to be still low since only few of them who can exemplify digital technology that can be implemented into several science concept. Therefore, training about technology implementation into science teaching and learning is necessary as a means to improve teachers’ technological knowledge.

The ultimate technology: the end of technology and the task of nature.

PubMed

Riis, Søren

2013-01-01

One of the most influential philosophers of the 20th century, Martin Heidegger (1889-1976), died prior to the remarkable cloning of the sheep Dolly and before Dr. Venter started his experiments on creating synthetic life, and he never explicitly discussed living technologies. However, by reinterpreting his notion of "modern technology," this article shows how it is possible to philosophically assess living technologies and to recognize ways in which Heidegger anticipated this phenomenon with his notion of cybernetics. The interpretation elucidates the fundamental process of technology becoming living and simultaneously presents living technology as the ultimate technology. The thesis of this article is that living technology is not just one more technology; rather, it is the perfection of technology as understood by Aristotle. Aristotle's thinking is in this way a key example of a profound reassessment of nature and technology. Aristotle clearly separates these two domains of being in his definition, but in doing so, he also connects them to one another in a highly influential way. Following this line of thought, the article finally offers an original perspective involving renewed respect for the perpetual self-unfolding nature of living technology.

Space and nuclear research and technology

NASA Technical Reports Server (NTRS)

1975-01-01

A fact sheet is presented on the space and nuclear research and technology program consisting of a research and technology base, system studies, system technology programs, entry systems technology, and experimental programs.

Spacecraft Bus and Platform Technology Development under the NASA ISPT Program

NASA Technical Reports Server (NTRS)

Anderson, David J.; Munk, Michelle M.; Pencil, Eric; Dankanich, John; Glaab, Louis; Peterson, Todd

2013-01-01

The In-Space Propulsion Technology (ISPT) program is developing spacecraft bus and platform technologies that will enable or enhance NASA robotic science missions. The ISPT program is currently developing technology in four areas that include Propulsion System Technologies (electric and chemical), Entry Vehicle Technologies (aerocapture and Earth entry vehicles), Spacecraft Bus and Sample Return Propulsion Technologies (components and ascent vehicles), and Systems/Mission Analysis. Three technologies are ready for near-term flight infusion: 1) the high-temperature Advanced Material Bipropellant Rocket (AMBR) engine providing higher performance; 2) NASA s Evolutionary Xenon Thruster (NEXT) ion propulsion system, a 0.6-7 kW throttle-able gridded ion system; and 3) Aerocapture technology development with investments in a family of thermal protection system (TPS) materials and structures; guidance, navigation, and control (GN&C) models of blunt-body rigid aeroshells; and aerothermal effect models. Two component technologies being developed with flight infusion in mind are the Advanced Xenon Flow Control System, and ultra-lightweight propellant tank technologies. Future direction for ISPT are technologies that relate to sample return missions and other spacecraft bus technology needs like: 1) Mars Ascent Vehicles (MAV); 2) multi-mission technologies for Earth Entry Vehicles (MMEEV) for sample return missions; and 3) electric propulsion for sample return and low cost missions. These technologies are more vehicle and mission-focused, and present a different set of technology development and infusion steps beyond those previously implemented. The Systems/Mission Analysis area is focused on developing tools and assessing the application of propulsion and spacecraft bus technologies to a wide variety of mission concepts. These in-space propulsion technologies are applicable, and potentially enabling for future NASA Discovery, New Frontiers, and sample return missions currently under consideration, as well as having broad applicability to potential Flagship missions. This paper provides a brief overview of the ISPT program, describing the development status and technology infusion readiness of in-space propulsion technologies in the areas of electric propulsion, Aerocapture, Earth entry vehicles, propulsion components, Mars ascent vehicle, and mission/systems analysis.

Spacecraft Bus and Platform Technology Development under the NASA ISPT Program

NASA Technical Reports Server (NTRS)

Anderson, David J.; Munk, Michelle M.; Pencil, Eric J.; Dankanich, John W.; Glaab, Louis J.; Peterson, Todd T.

2013-01-01

The In-Space Propulsion Technology (ISPT) program is developing spacecraft bus and platform technologies that will enable or enhance NASA robotic science missions. The ISPT program is currently developing technology in four areas that include Propulsion System Technologies (electric and chemical), Entry Vehicle Technologies (aerocapture and Earth entry vehicles), Spacecraft Bus and Sample Return Propulsion Technologies (components and ascent vehicles), and Systems/Mission Analysis. Three technologies are ready for near-term flight infusion: 1) the high-temperature Advanced Material Bipropellant Rocket (AMBR) engine providing higher performance 2) NASAs Evolutionary Xenon Thruster (NEXT) ion propulsion system, a 0.6-7 kW throttle-able gridded ion system and 3) Aerocapture technology development with investments in a family of thermal protection system (TPS) materials and structures guidance, navigation, and control (GN&C) models of blunt-body rigid aeroshells and aerothermal effect models. Two component technologies being developed with flight infusion in mind are the Advanced Xenon Flow Control System, and ultra-lightweight propellant tank technologies. Future direction for ISPT are technologies that relate to sample return missions and other spacecraft bus technology needs like: 1) Mars Ascent Vehicles (MAV) 2) multi-mission technologies for Earth Entry Vehicles (MMEEV) for sample return missions and 3) electric propulsion for sample return and low cost missions. These technologies are more vehicle and mission-focused, and present a different set of technology development and infusion steps beyond those previously implemented. The Systems/Mission Analysis area is focused on developing tools and assessing the application of propulsion and spacecraft bus technologies to a wide variety of mission concepts. These in-space propulsion technologies are applicable, and potentially enabling for future NASA Discovery, New Frontiers, and sample return missions currently under consideration, as well as having broad applicability to potential Flagship missions. This paper provides a brief overview of the ISPT program, describing the development status and technology infusion readiness of in-space propulsion technologies in the areas of electric propulsion, Aerocapture, Earth entry vehicles, propulsion components, Mars ascent vehicle, and mission/systems analysis.

Troubling distinctions: a semiotics of the nursing/technology relationship.

PubMed

Sandelowski, M

1999-09-01

I consider the discursive practices that have served conceptually and ontologically to trouble the boundaries between nursing and technology: between nurse/human/subject and machine/non-human/object. Nursing and technology have been semiotically related largely by two processes: (a) by the metaphor that depicts nursing as technology and (b) by opposition, or as not like and even in conflict with technology. Less frequently but no less significantly, nursing and technology have been semiotically linked (c) by the metaphor that depicts technology as nursing and (d) by metonymy, or by word or picture juxtapositions of nursing with technology. The troubling distinctions between nursing and technology suggest yet another reason why the construction of difference continues to elude nursing.

Technology and Economics, Inc. Technology Application Team

NASA Technical Reports Server (NTRS)

Ballard, T.; Macfadyen, D. J.

1981-01-01

Technology + Economics, Inc. (T+E), under contract to the NASA Headquarters Technology Transfer Division, operates a Technology Applications Team (TATeam) to assist in the transfer of NASA-developed aerospace technology. T+E's specific areas of interest are selected urban needs at the local, county, and state levels. T+E contacts users and user agencies at the local, state, and county levels to assist in identifying significant urban needs amenable to potential applications of aerospace technology. Once viable urban needs have been identified in this manner, or through independent research, T+E searches the NASA technology database for technology and/or expertise applicable to the problem. Activities currently under way concerning potential aerospace applications are discussed.

CSTI Earth-to-orbit propulsion research and technology program overview

NASA Technical Reports Server (NTRS)

Gentz, Steven J.

1993-01-01

NASA supports a vigorous Earth-to-orbit (ETO) research and technology program as part of its Civil Space Technology Initiative. The purpose of this program is to provide an up-to-date technology base to support future space transportation needs for a new generation of lower cost, operationally efficient, long-lived and highly reliable ETO propulsion systems by enhancing the knowledge, understanding and design methodology applicable to advanced oxygen/hydrogen and oxygen/hydrocarbon ETO propulsion systems. Program areas of interest include analytical models, advanced component technology, instrumentation, and validation/verification testing. Organizationally, the program is divided between technology acquisition and technology verification as follows: (1) technology acquisition; and (2) technology verification.

Digital SPC switching technology: Foreign technology assessment

NASA Astrophysics Data System (ADS)

Fischman, Kurt; Jorstad, Norman D.

1990-12-01

This paper provides a foreign technology assessment of digital switching technology. Leading suppliers of digital switching technology are identified; although the United States holds a large part of the market, major companies in France, Sweden, Japan, the U.K., and Germany are also important. These countries, along with Belgium and Canada, are the most innovative and technically advanced. A listing is provided of transfers of digital switching technology to non-COCOM countries through licensing and joint ventures which reflects the widespread dissemination of this technology. Detailed technical specifications are provided for selected digital switching systems worldwide. The report concludes that considering the degree to which the technology is in place, that control of digital switching technology may not be feasible.

From Research to Flight: Thinking About Implementation While Performing Fundamental Research

NASA Technical Reports Server (NTRS)

Johnson, Les

2010-01-01

This slide presentation calls for a strategy to implement new technologies. Such a strategy would allow advanced space transportation technologies to mature for exploration beyond Earth orbit. It discusses the difference between technology push versus technology pull. It also reviews the three basic technology readiness levels (TRL). The presentation traces examples of technology development to flight application: the Space Shuttle Main Engine Advanced Health Management System, the Friction Stir Welding technology the (auto-adjustable pin tool). A couple of technologies currently not in flight, but are being reviewed for potential use are: cryogenic fluid management (CFM), and solar sail propulsion. There is also an attempt to explain why new technologies are so difficult to field.

Methodologies for Optimum Capital Expenditure Decisions for New Medical Technology

PubMed Central

Landau, Thomas P.; Ledley, Robert S.

1980-01-01

This study deals with the development of a theory and an analytical model to support decisions regarding capital expenditures for complex new medical technology. Formal methodologies and quantitative techniques developed by applied mathematicians and management scientists can be used by health planners to develop cost-effective plans for the utilization of medical technology on a community or region-wide basis. In order to maximize the usefulness of the model, it was developed and tested against multiple technologies. The types of technologies studied include capital and labor-intensive technologies, technologies whose utilization rates vary with hospital occupancy rate, technologies whose use can be scheduled, and limited-use and large-use technologies.

KSC Tech Transfer News, Volume 5, No. 1

NASA Technical Reports Server (NTRS)

Buckingham, Bruce (Editor)

2012-01-01

In October 2011, the White House released a presidential memorandum titled "Accelerating Technology Transfer and Commercialization of Federal Research in Support of High-Growth Businesses." It emphasized the importance of technology transfer as a driver of successful innovation to fuel economic growth, create jobs, and make U.S. industries more competitive in a global market. In response to this memorandum, NASA developed a 5-year plan for accelerating its own technology transfer activities. This plan outlines key objectives for enhancing NASA's ability to increase the rate, volume, and quality of technology transfers to industry, academia, and other Government agencies. By doing so, we are increasing the economic impact and public benefit of Federal technology investments. In addition, NASA established technology transfer as a key element of one of its Agency High Priority Performance Goals: "Enable bold new missions and make new technologies available to Government agencies and U.S. industry."What does this mean to you? In the broadest sense, NASA defines technology transfer as the utilization of NASA's technological assets- technologies, innovations, unique facilities and equipment, and technical expertise- by public and private sectors to benefit the Nation. So, if your job involves developing new technologies, writing new software, creating innovative ways to do business, performing research, or developing new technical capabilities, you could be contributing to Kennedy Space Center's (KSC) technology transfer activities by creating the technological assets that may one day be used by external partners. Furthermore, anytime you provide technical expertise to external partners, you're participating in technology transfer. The single most important step you can take to support the technology transfer process is to report new technologies and innovations ro the Technology Transfer Office. This is the critical first step in fueling the technology transfer pipeline. This is also a requirement for all Federal employees (see NPD 2091.1 B) and most NASA contractors. Detailed information on when, where, and how ro report new technology is provided on the following page. In addition, it's important that all detailed-oriented discussions about technology between NASA and external partners are documented or that they occur under formal agreements such as Space Act Agreements and Nondisclosure Agreements. Our office can assist you in putting these agreements into place, protecting NASA's interests, and providing the means to accurately measure the Agency's technology transfer activities. Technology transfer is everyone's responsibility. We need your help to ensure that NASA remains the leader in Federal technology transfer, and that the great work done at KSC provides the maximum economic and societal benefit to the Nation.

A Study of the Factors Associated with Successful Technology Transfer and their Applicability to Air Force Technology Transfers.

DTIC Science & Technology

1995-09-01

transfer project. (D) 8a Organization has a technology transfer organization. (D,A) 10a Marketing and advertising of technologies targeted to relevant...Entrepreneurial (D) Developer: 10A: Marketing and advertising of technologies targeted to relevant industries. Most developers indicate that they marketed...regard to marketing and advertising . 10B: Technology maturation supported by internal units or by contracting out. Technology maturation is the

National transportation technology plan

DOT National Transportation Integrated Search

2000-05-01

The National Science and Technology Council (NSTC) Committee on Technology, Subcommittee on Transportation Research and Development (R&D), has created a National Transportation Technology Plan that builds on the initial Technology Plan released in 19...

ENVIRONMENTAL TECHNOLOGY VERIFICATION, TEST REPORT OF MOBILE SOURCE EMISSIONS CONTROL DEVICES: CLEAN DIESEL TECHNOLOGIES FUEL-BORNE CATALYST WITH MITSUI/PUREARTH CATALYZED WIRE MESH FILTER

EPA Science Inventory

The Environmental Technology Verification report discusses the technology and performance of the Fuel-Borne Catalyst with Mitsui/PUREarth Catalyzed Wire Mesh Filter manufactured by Clean Diesel Technologies, Inc. The technology is a platinum/cerium fuel-borne catalyst in commerci...

Technology Education Symposium II. Program Theme: "Technological Literacy" (Menomonie, Wisconsin, May 1-2, 1981).

ERIC Educational Resources Information Center

Smalley, Lee, Ed.

This monograph summarizes 21 presentations from a symposium whose theme was technological literacy--an understanding of the impact of technological descisions. These presentations are divided into five categories. The six presentations in the section, The Context of Technology Education, focus on technological literacy for living in today's…

Information Communication Technology and Politics: A Synthesized Analysis of the Impacts of Information Technology on Voter Participation in Kenya

ERIC Educational Resources Information Center

Tsuma, Clive Katiba

2011-01-01

The availability of political information throughout society made possible by the evolution of contemporary information communication technology has precipitated conflicting debate regarding the effects of technology use on real life political participation. Proponents of technology argue that the use of new information technology stimulates…

Mars base technology program overview

NASA Technical Reports Server (NTRS)

Chu, Chneg-Chih; Hayati, Samad A.; Udomkesmalee, Suraphol

2005-01-01

In this paper, we present an overview of the current technology portfolio for Mars Base Technology Program. Brief descriptions of the awarded technologies and the high-priority areas in both NRAs are provided to show the current focus of MTP. We also present the approach that MTP uses to evaluate technology maturity for each of the technology tasks.

Too Much Too Fast: The Dangers of Technological Momentum.

ERIC Educational Resources Information Center

Dyer, Dean

This paper discusses the dangers of technological momentum. Technological momentum is defined as the increase in the rate of the evolution of technology, its infusion into societal tasks and recreations, society's dependence on technology, and the impact of technology on society. Topics of discussion include changes in response to user needs,…

Hot Technologies for K-12 Schools: The 2005 Guide for Technology Decision Makers. COSN's Emerging Technologies Series

ERIC Educational Resources Information Center

Vockley, Martha, Ed.

2004-01-01

As technology companies introduce innovative products and services for the education market, school districts have the opportunity to invest in technologies designed to improve instruction and operations--from teaching, learning and assessments to organizational efficiency. Perhaps the greatest promise of anticipated technologies is their…

Technology Transience and the Challenges It Poses to Higher Education

ERIC Educational Resources Information Center

Amirault, Ray J.

2015-01-01

Today's technologies come and go at an alarming rate, and the length of time any one technology, either software or hardware, exists before being supplanted by a newer technology is growing ever shorter. For anyone working within the field of instructional technology, this rapid replacement rate of technologies can hold immense implications for…

Aspiring School Administrators' Perceived Ability to Meet Technology Standards and Technological Needs for Professional Development

ERIC Educational Resources Information Center

Yu, Chien; Prince, Debra Lindsey

2016-01-01

The merits of technology in general and of educational technology specifically are well documented. The use of educational technology has been shown to improve teaching and learning and the overall educational quality of schools. However, the successful integration of educational technology in schools hinges on school administrators' technology…

Under Construction: Minority Girls Becoming Technologically Fluent in an Urban After-School Program

ERIC Educational Resources Information Center

De La Pena, Yvonne

2012-01-01

Technological fluency involves having a deep understanding of information technology as well as an identity as someone who engages with technology in meaningful and complex ways. Hence, it is more fruitful to think about individuals not as developing technological fluency but rather as becoming technologically fluent. Although physical access to…

76 FR 52721 - President's Council of Advisors on Science and Technology; Notice of Meeting: Partially Closed...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-23

... OFFICE OF SCIENCE AND TECHNOLOGY POLICY President's Council of Advisors on Science and Technology... Office of Science and Technology Policy (OSTP). PCAST is co-chaired by Dr. John P. Holdren, Assistant to the President for Science and Technology, and Director, Office of Science and Technology Policy...

76 FR 7593 - President's Council of Advisors on Science and Technology; Notice of Meeting: Partially Closed...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-10

... OFFICE OF SCIENCE AND TECHNOLOGY POLICY President's Council of Advisors on Science and Technology... Office of Science and Technology Policy (OSTP). PCAST is co-chaired by Dr. John P. Holdren, Assistant to the President for Science and Technology, and Director, Office of Science and Technology Policy...

Discerning Technological Systems Related to Everyday Objects: Mapping the Variation in Pupils' Experience

ERIC Educational Resources Information Center

Svensson, Maria; Ingerman, Ake

2010-01-01

Understanding technology today implies more than being able to use the technological objects present in our everyday lives. Our society is increasingly integrated with technological systems, of which technological objects, and their function, form a part. Technological literacy in that context implies understanding how knowledge is constituted in…

Understanding Technology Literacy: A Framework for Evaluating Educational Technology Integration

ERIC Educational Resources Information Center

Davies, Randall S.

2011-01-01

Federal legislation in the United States currently mandates that technology be integrated into school curricula because of the popular belief that learning is enhanced through the use of technology. The challenge for educators is to understand how best to teach with technology while developing the technological expertise of their students. This…

How New Technologies Have (and Have Not) Changed Teaching and Learning in Schools

ERIC Educational Resources Information Center

Halverson, Richard; Smith, Annette

2010-01-01

Information technologies have reshaped teaching and learning in schools, but often not in ways anticipated by technology proponents. This paper proposes a contrast between technologies for learning and technologies for learners to explain how technologies influence teaching and learning in and out of schools. Schools have made significant use of…

The Ecology of Technological Progress: How Symbiosis and Competition Affect the Growth of Technology Domains

ERIC Educational Resources Information Center

Carnabuci, Gianluca

2010-01-01

We show that the progress of technological knowledge is an inherently ecological process, wherein the growth rate of each technology domain depends on dynamics occurring in "other" technology domains. We identify two sources of ecological interdependence among technology domains. First, there are symbiotic interdependencies, implying…

Technology and the Nature of Man: Biological Considerations. An Occasional Paper on Man/Society/Technology.

ERIC Educational Resources Information Center

Sherwood, Lauralee

This seminar paper explores biological aspects of the man-technology relationship. From man's beginning and continuing into the future, technology is interwoven extensively in the biological fabric of man. Five facets of the biology-technology interaction are examined: (1) technological innovations enabling man to learn about his biological…

What Is Educational Technology? An Inquiry into the Meaning, Use, and Reciprocity of Technology

ERIC Educational Resources Information Center

Lakhana, Arun

2014-01-01

This position paper explores the ambiguity of technology, toward refined understanding of Educational Technology. The purpose of education is described by John Dewey as growing, or habitual learning. Two philosophical conceptions of technology are reviewed. Dewey positions inquiry as a technology that creates knowledge. Val Dusek offers a…

Current Trends in Higher Education Technology: Simulation

ERIC Educational Resources Information Center

Damewood, Andrea M.

2016-01-01

This paper is focused on how technology in use changes over time, and the current trend of simulation technology as a supported classroom technology. Simulation-based training as a learning tool is discussed within the context of adult learning theories, as is the technology used and how today's higher education technology administrators support…

Science-Technology-Society or Technology-Society-Science? Insights from an Ancient Technology

ERIC Educational Resources Information Center

Lee, Yeung Chung

2010-01-01

Current approaches to science-technology-society (STS) education focus primarily on the controversial socio-scientific issues that arise from the application of science in modern technology. This paper argues for an interdisciplinary approach to STS education that embraces science, technology, history, and social and cultural studies. By employing…

A Framework for Seeking the Connections between Technology, Pedagogy, and Culture: A Study in the Maldives

ERIC Educational Resources Information Center

Adam, Aminath

2017-01-01

Educational technology researchers have often overlooked the effect of culture on teachers' use of digital technologies in their pedagogical practice. Several technology integration models, such as the Technology Adoption Model (TAM) and Technological, Pedagogical and Content Knowledge (TPACK), have also failed to explain the connections between…

Developing Indicators for a Classroom Observation Tool on Pedagogy and Technology Integration: A Delphi Study

ERIC Educational Resources Information Center

Elmendorf, Douglas C.; Song, Liyan

2015-01-01

Rapid advances in technology and increased access to technology tools have created new instructional demands and expectations on teachers. Due to the ubiquitous presence of technology in K-12 schools, teachers are being observed on both their pedagogical and technology integration practices. Applying the technological pedagogical and content…

Evolution of technology convergence networks in Korea: Characteristics of temporal changes in R&D according to institution type.

PubMed

Choi, Jae Young; Jeong, Seongkyoon; Jung, Jung-Kyu

2018-01-01

This study investigates the temporal changes in development of technology convergence networks by institution type, i.e., public research institute (PRI), university and industry. Using the co-classification of technological domains of patents, we identified technology convergence of Korean patents, which were filed at Korea Intellectual Properties Office (KIPO) from 1997 to 2011. We conducted a network analysis at the technology level to search for the key technology fields and frequent instances of technology convergence. The results show that technology convergence networks have grown significantly in the recent period regardless of the institution type. While industries started to conspicuously engage in technology convergence in the late 1990s, universities or PRIs did not do so until the mid-2000s. This discrepancy in the phase of technology convergence is attributed to the temporal difference in R&D stage (e.g., basic research and commercial product development). Our findings imply that corporal and governmental R&D management decision on promising technology fields will be more effective if the decision makers carefully consider the type of R&D entity in analyzing technological landscapes.

Technology for small spacecraft

NASA Technical Reports Server (NTRS)

1994-01-01

This report gives the results of a study by the National Research Council's Panel on Small Spacecraft Technology that reviewed NASA's technology development program for small spacecraft and assessed technology within the U.S. government and industry that is applicable to small spacecraft. The panel found that there is a considerable body of advanced technology currently available for application by NASA and the small spacecraft industry that could provide substantial improvement in capability and cost over those technologies used for current NASA small spacecraft. These technologies are the result of developments by commercial companies, Department of Defense agencies, and to a lesser degree NASA. The panel also found that additional technologies are being developed by these same entities that could provide additional substantial improvement if development is successfully completed. Recommendations for future technology development efforts by NASA across a broad technological spectrum are made.

SHARED TECHNOLOGY TRANSFER PROGRAM

DOE Office of Scientific and Technical Information (OSTI.GOV)

GRIFFIN, JOHN M. HAUT, RICHARD C.

2008-03-07

The program established a collaborative process with domestic industries for the purpose of sharing Navy-developed technology. Private sector businesses were educated so as to increase their awareness of the vast amount of technologies that are available, with an initial focus on technology applications that are related to the Hydrogen, Fuel Cells and Infrastructure Technologies (Hydrogen) Program of the U.S. Department of Energy. Specifically, the project worked to increase industry awareness of the vast technology resources available to them that have been developed with taxpayer funding. NAVSEA-Carderock and the Houston Advanced Research Center teamed with Nicholls State University to catalog NAVSEA-Carderockmore » unclassified technologies, rated the level of readiness of the technologies and established a web based catalog of the technologies. In particular, the catalog contains technology descriptions, including testing summaries and overviews of related presentations.« less

Technology and the hydra of terrorism?

DOE Office of Scientific and Technical Information (OSTI.GOV)

LePoire, D. J.; Glenn, J. C.; Environmental Assessment

2007-02-01

In the application of new technologies that address the terrorism problem, an objective is to ensure that the technology does not cause more problems than it solves. Potential new technologies, including convergences of genomics, robotics, information technology, and nanotechnology, might rapidly develop. As with any technological advance, each of these offers a mixture of benefits and risks. At first, a direct approach is reviewed by looking at how these technologies might deter the motive, means, and opportunity for terrorist activities. While there are many potential deterrence applications, other issues are identified that might cause unintended problems in the system. Somemore » of these problems include the possible contribution to terrorist motives by increasing stresses toward divisiveness in society, terrorist means through the development of dual-use technologies, or terrorist opportunities by further developing technological vulnerabilities. Next, a more systemic approach is taken by reviewing a wider range of issues, such as resource availability, management of science and technology, and general societal trends. The balance between technological change and social response is important in realizing benefits while mitigating unintended consequences such as harmful uses through terrorist actions. To explore issues concerning this balance, possible technological development scenarios are reviewed, including the possibility of accelerating or slowing technological development. Some recent recommendations are considered within this context. The need for a balance between technological and social response in this asymmetric situation suggests that the benefits of a rapid technological response against terrorism might not be as large as those observed during World War II.« less

Subjective Technology Adaptivity Predicts Technology Use in Old Age.

PubMed

Kamin, Stefan T; Lang, Frieder R; Beyer, Anja

2017-01-01

To date, not much is known about the psychological and motivational factors underlying technology use in late life. What are the interindividual determinants that lead older adults to invest in using technological innovations despite the age-related physiological changes that impose challenges on behavioral plasticity in everyday life? This research explores interindividual differences in subjective technology adaptivity - a general technology-related motivational resource that accounts for technology use in late life. More specifically, we investigate the influence of this factor relative to demographic characteristics, personality traits, and functional limitations in a longitudinal sample of community-dwelling older adults. We report results from a paper-and-pencil survey with 136 older adults between 59 and 92 years of age (mean = 71.4, SD = 7.4). Of those participants, 77 participated in a 2-year follow-up. We assessed self-reports of technology use, subjective technology adaptivity, functional limitations, and the personality traits openness to new experiences and neuroticism. Higher levels of subjective technology adaptivity were associated with technology use at the first measurement as well as increased use over the course of 2 years. Subjective technology adaptivity is a significant predictor of technology use in old age. Our findings contribute to improving the understanding of interindividual differences when using technological innovation in late life. Moreover, our findings have implications in the context of user involvement and may contribute to the successful development of innovative technology for older adults. © 2017 S. Karger AG, Basel.

Home care technology through an ability expectation lens.

PubMed

Wolbring, Gregor; Lashewicz, Bonnie

2014-06-20

Home care is on the rise, and its delivery is increasingly reliant on an expanding variety of health technologies ranging from computers to telephone "health apps" to social robots. These technologies are most often predicated on expectations that people in their homes (1) can actively interact with these technologies and (2) are willing to submit to the action of the technology in their home. Our purpose is to use an "ability expectations" lens to bring together, and provide some synthesis of, the types of utility and disadvantages that can arise for people with disabilities in relation to home care technology development and use. We searched the academic databases Scopus, Web of Science, EBSCO ALL, IEEE Xplore, and Compendex to collect articles that had the term "home care technology" in the abstract or as a topic (in the case of Web of Science). We also used our background knowledge and related academic literature pertaining to self-diagnosis, health monitoring, companionship, health information gathering, and care. We examined background articles and articles collected through our home care technology search in terms of ability expectations assumed in the presentation of home care technologies, or discussed in relation to home care technologies. While advances in health care support are made possible through emerging technologies, we urge critical examination of such technologies in terms of implications for the rights and dignity of people with diverse abilities. Specifically, we see potential for technologies to result in new forms of exclusion and powerlessness. Ableism influences choices made by funders, policy makers, and the public in the development and use of home health technologies and impacts how people with disabilities are served and how useful health support technologies will be for them. We urge continued critical examination of technology development and use according to ability expectations, and we recommend increasing incorporation of participatory design processes to counteract potential for health support technology to render people with disabilities technologically excluded and powerless.

Educational technologies in health sciences libraries: teaching technology skills.

PubMed

Hurst, Emily J

2014-01-01

As technology rapidly changes, libraries remain go-to points for education and technology skill development. In academic health sciences libraries, trends suggest librarians provide more training on technology topics than ever before. While education and training have always been roles for librarians, providing technology training on new mobile devices and emerging systems requires class creation and training capabilities that are new to many librarians. To appeal to their users, many health sciences librarians are interested in developing technology-based classes. This column explores the question: what skills are necessary for developing and teaching technology in an academic health sciences library setting?

National Technology Center and photonics

NASA Astrophysics Data System (ADS)

Vlannes, Nickolas P.

1992-05-01

A National Technology Center is proposed in order to meet the international challenges to the economy and security of the United States. This center would be tasked with the acquisition, analysis, assessment, and dissemination of worldwide scientific and technical information and data; technology transfer to the United States; and research and development in information and library sciences and technology. The National Technology Center would form a national network linking centers of excellence and expertise, and maintain a national technology library. With these functions, the National Technology Center has inherent requirements for technologies based on photonics, and will further motivate developments in this field.