[Optimization study on extraction technology of the seed of Ziziphus jujuba var. spinosa by orthogonal design with multi-targets].

PubMed

Wang, Xiao-liang; Zhang, Yu-jie; Chen, Ming-xia; Wang, Ze-feng

2005-05-01

To optimize extraction technology of the seed of Ziziphus jujuba var. spinosa with the targets of the total saponin, total jujuboside A and B and total flavonoids. In the method of one-way and orthogonal tests, ethanol concentration, amount of ethanol, extraction time and extraction times were the factors in orthogonal test, and each factor with three levels. Ethanol concentration and extraction times had significant effect on all the targets, other factors should be selected in accordance with production practice. The best extraction technology is to extract for three times with 8 fold ethanol solution (60%), and 1.5 h each time.

CHLORINATED SOLVENT CONTAMINATED SOILS AND GROUNDWATER: FIELD APPLICATION OF THE SOLVENT EXTRACTION RESIDUAL BIOTREATMENT TECHNOLOGY

EPA Science Inventory

A pilot scale demonstration of the Solvent Extraction Residual Biotreatment (SERB) technology was conducted at the former Sage's Dry Cleaner site in Jacksonville, FL. The SERB technology is a treatment train approach to complete site restoration, which combines an active in situ...

Phytosterols and their extraction from various plant matrices using supercritical carbon dioxide: a review.

PubMed

Uddin, Md Salim; Sarker, Md Zaidul Islam; Ferdosh, Sahena; Akanda, Md Jahurul Haque; Easmin, Mst Sabina; Bt Shamsudin, Siti Hadijah; Bin Yunus, Kamaruzzaman

2015-05-01

Phytosterols provide important health benefits: in particular, the lowering of cholesterol. From environmental and commercial points of view, the most appropriate technique has been searched for extracting phytosterols from plant matrices. As a green technology, supercritical fluid extraction (SFE) using carbon dioxide (CO2) is widely used to extract bioactive compounds from different plant matrices. Several studies have been performed to extract phytosterols using supercritical CO2 (SC-CO2) and this technology has clearly offered potential advantages over conventional extraction methods. However, the efficiency of SFE technology fully relies on the processing parameters, chemistry of interest compounds, nature of the plant matrices and expertise of handling. This review covers SFE technology with particular reference to phytosterol extraction using SC-CO2. Moreover, the chemistry of phytosterols, properties of supercritical fluids (SFs) and the applied experimental designs have been discussed for better understanding of phytosterol solubility in SC-CO2. © 2014 Society of Chemical Industry.

Preparation of acellular scaffold for corneal tissue engineering by supercritical carbon dioxide extraction technology.

PubMed

Huang, Yi-Hsun; Tseng, Fan-Wei; Chang, Wen-Hsin; Peng, I-Chen; Hsieh, Dar-Jen; Wu, Shu-Wei; Yeh, Ming-Long

2017-08-01

In this study, we developed a novel method using supercritical carbon dioxide (SCCO 2 ) to prepare acellular porcine cornea (APC). Under gentle extraction conditions using SCCO 2 technology, hematoxylin and eosin staining showed that cells were completely lysed, and cell debris, including nuclei, was efficiently removed from the porcine cornea. The SCCO 2 -treated corneas exhibited intact stromal structures and appropriate mechanical properties. Moreover, no immunological reactions and neovascularization were observed after lamellar keratoplasty in rabbits. All transplanted grafts and animals survived without complications. The transplanted APCs were opaque after the operation but became transparent within 2weeks. Complete re-epithelialization of the transplanted APCs was observed within 4weeks. In conclusion, APCs produced by SCCO 2 extraction technology could be an ideal and useful scaffold for corneal tissue engineering. We decellularized the porcine cornea using SCCO 2 extraction technology and investigated the characteristics, mechanical properties, and biocompatibility of the decellularized porcine cornea by lamellar keratoplasty in rabbits. To the best of our knowledge, this is the first report describing the use of SCCO 2 extraction technology for preparation of acellular corneal scaffold. We proved that the cellular components of porcine corneas had been efficiently removed, and the biomechanical properties of the scaffold were well preserved by SCCO 2 extraction technology. SCCO 2 -treated corneas maintained optical transparency and exhibited appropriate strength to withstand surgical procedures. In vivo, the transplanted corneas showed no evidence of immunological reactions and exhibited good biocompatibility and long-term stability. Our results suggested that the APCs developed by SCCO 2 extraction technology could be an ideal and useful scaffold for corneal replacement and corneal tissue engineering. Copyright © 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

GREEN AND SUSTAINABLE REMEDIATION BEST MANAGEMENT PRACTICES

DTIC Science & Technology

2016-09-07

adoption. The technologies covered include air sparging, biosparging, soil vapor extraction (SVE), enhanced reductive dechlorination (ERD), in situ...RPM Remedial Project Manager SCR selective catalytic reduction SEE steam enhanced extraction SVE soil vapor extraction TCE trichloroethene...further promote their adoption. The technologies covered include air sparging, biosparging, soil vapor extraction (SVE), enhanced reductive

[Application of genetic algorithm in blending technology for extractions of Cortex Fraxini].

PubMed

Yang, Ming; Zhou, Yinmin; Chen, Jialei; Yu, Minying; Shi, Xiufeng; Gu, Xijun

2009-10-01

To explore the feasibility of genetic algorithm (GA) on multiple objective blending technology for extractions of Cortex Fraxini. According to that the optimization objective was the combination of fingerprint similarity and the root-mean-square error of multiple key constituents, a new multiple objective optimization model of 10 batches extractions of Cortex Fraxini was built. The blending coefficient was obtained by genetic algorithm. The quality of 10 batches extractions of Cortex Fraxini that after blending was evaluated with the finger print similarity and root-mean-square error as indexes. The quality of 10 batches extractions of Cortex Fraxini that after blending was well improved. Comparing with the fingerprint of the control sample, the similarity was up, but the degree of variation is down. The relative deviation of the key constituents was less than 10%. It is proved that genetic algorithm works well on multiple objective blending technology for extractions of Cortex Fraxini. This method can be a reference to control the quality of extractions of Cortex Fraxini. Genetic algorithm in blending technology for extractions of Chinese medicines is advisable.

Getting to low-cost algal biofuels: A monograph on conventional and cutting-edge harvesting and extraction technologies

DOE PAGES

Coons, James E.; Kalb, Daniel M.; Dale, Taraka; ...

2014-08-31

Among the most formidable challenges to algal biofuels is the ability to harvest algae and extract intracellular lipids at low cost and with a positive energy balance. Here, we construct two paradigms that contrast energy requirements and costs of conventional and cutting-edge Harvesting and Extraction (H&E) technologies. By application of the parity criterion and the moderate condition reference state, an energy–cost paradigm is created that allows 1st stage harvesting technologies to be compared with easy reference to the National Alliance for Advanced Biofuels and Bioproducts (NAABB) target of $0.013/gallon of gasoline equivalent (GGE) and to the U.S. DOE's Bioenergy Technologiesmore » Office 2022 cost metrics. Drawing from the moderate condition reference state, a concentration-dependency paradigm is developed for extraction technologies, making easier comparison to the National Algal Biofuels Technology Roadmap (NABTR) target of less than 10% total energy. This monograph identifies cost-bearing factors for a variety of H&E technologies, describes a design basis for ultrasonic harvesters, and provides a framework to measure future technological advancements toward reducing H&E costs. Finally, we show that ultrasonic harvesters and extractors are uniquely capable of meeting both NAABB and NABTR targets. Ultrasonic technologies require further development and scale-up before they can achieve low-cost performance at industrially relevant scales. But, the advancement of this technology would greatly reduce H&E costs and accelerate the commercial viability of algae-based biofuels.« less

[Nasal submicron emulsion of Scutellariae Radix extract preparation technology research based on phase transfer of solute technology].

PubMed

Shi, Ya-jun; Shi, Jun-hui; Chen, Shi-bin; Yang, Ming

2015-07-01

Based on the demand of nasal drug delivery high drug loadings, using the unique phase transfer of solute, integrating the phospholipid complex preparation and submicron emulsion molding process of Scutellariae Radix extract, the study obtained the preparation of the high drug loadings submicron emulsion of Scutellariae Radix extract. In the study of drug solution dispersion method, the uniformity of drug dispersed as the evaluation index, the traditional mixing method, grinding, homogenate and solute phase transfer technology were investigated, and the solute phase transfer technology was adopted in the last. With the adoption of new technology, the drug loading capacity reached 1.33% (phospholipid complex was 4%). The drug loading capacity was improved significantly. The transfer of solute method and timing were studied as follows,join the oil phase when the volume of phospholipid complex anhydrous ethanol solution remaining 30%, the solute phase transfer was completed with the continued recycling of anhydrous ethanol. After drug dissolved away to oil phase, the preparation technology of colostrum was determined with the evaluation index of emulsion droplet form. The particle size of submicron emulsion, PDI and stability parameters were used as evaluation index, orthogonal methodology were adopted to optimize the submicron emulsion ingredient and main influential factors of high pressure homogenization technology. The optimized preparation technology of Scutellariae Radix extract nasal submicron emulsion is practical and stable.

Technology transfer opportunities: patent license: electrochemical technique for introducing and redistributing ionic species into the earth

USGS Publications Warehouse

Leinz, Reinhard

1996-01-01

Scientists at the U.S. Geological Survey have expanded applications of the Chim electrode, technology used to perform partial geochemical extractions from soils. Recent applications of the the improved electrode technology show that geochemical extraction efficiencies can be improved by 2 orders of magnitude or better to about 30%.

Green extraction of natural products: concept and principles.

PubMed

Chemat, Farid; Vian, Maryline Abert; Cravotto, Giancarlo

2012-01-01

The design of green and sustainable extraction methods of natural products is currently a hot research topic in the multidisciplinary area of applied chemistry, biology and technology. Herein we aimed to introduce the six principles of green-extraction, describing a multifaceted strategy to apply this concept at research and industrial level. The mainstay of this working protocol are new and innovative technologies, process intensification, agro-solvents and energy saving. The concept, principles and examples of green extraction here discussed, offer an updated glimpse of the huge technological effort that is being made and the diverse applications that are being developed.

Applications of aerospace technology to petroleum extraction and reservoir engineering

NASA Technical Reports Server (NTRS)

Jaffe, L. D.; Back, L. H.; Berdahl, C. M.; Collins, E. E., Jr.; Gordon, P. G.; Houseman, J.; Humphrey, M. F.; Hsu, G. C.; Ham, J. D.; Marte, J. E.;

Terra-Kleen Response Group, Inc. Solvent Extraction Technology Rapid Commercialization Initiative Report

EPA Science Inventory

Terra-Kleen Response Group Inc. (Terra-Kleen), has commercialized a solvent extraction technology that uses a proprietary extraction solvent to transfer organic constituents from soil to a liquid phase in a batch process at ambient temperatures. The proprietary solvent has a rel...

RESOURCES CONSERVATIONS COMPANY - B.E.S.T. SOLVENT EXTRACTION TECHNOLOGY - APPLICATIONS ANALYSIS REPORT

EPA Science Inventory

This document is an evaluation of the performance of the Resources Conservation Company (RCC) Basic Extractive Sludge Treatment (B.E.S.T.®) solvent extraction technology and its applicability as a treatment technique for soils, sediments, and sludges contaminated with organics. B...

Innovative Alternative Technologies to Extract Carotenoids from Microalgae and Seaweeds

PubMed Central

Poojary, Mahesha M.; Barba, Francisco J.; Aliakbarian, Bahar; Donsì, Francesco; Pataro, Gianpiero; Dias, Daniel A.; Juliano, Pablo

2016-01-01

Marine microalgae and seaweeds (microalgae) represent a sustainable source of various bioactive natural carotenoids, including β-carotene, lutein, astaxanthin, zeaxanthin, violaxanthin and fucoxanthin. Recently, the large-scale production of carotenoids from algal sources has gained significant interest with respect to commercial and industrial applications for health, nutrition, and cosmetic applications. Although conventional processing technologies, based on solvent extraction, offer a simple approach to isolating carotenoids, they suffer several, inherent limitations, including low efficiency (extraction yield), selectivity (purity), high solvent consumption, and long treatment times, which have led to advancements in the search for innovative extraction technologies. This comprehensive review summarizes the recent trends in the extraction of carotenoids from microalgae and seaweeds through the assistance of different innovative techniques, such as pulsed electric fields, liquid pressurization, supercritical fluids, subcritical fluids, microwaves, ultrasounds, and high-pressure homogenization. In particular, the review critically analyzes technologies, characteristics, advantages, and shortcomings of the different innovative processes, highlighting the differences in terms of yield, selectivity, and economic and environmental sustainability. PMID:27879659

Innovative Alternative Technologies to Extract Carotenoids from Microalgae and Seaweeds.

PubMed

Poojary, Mahesha M; Barba, Francisco J; Aliakbarian, Bahar; Donsì, Francesco; Pataro, Gianpiero; Dias, Daniel A; Juliano, Pablo

2016-11-22

Marine microalgae and seaweeds (microalgae) represent a sustainable source of various bioactive natural carotenoids, including β-carotene, lutein, astaxanthin, zeaxanthin, violaxanthin and fucoxanthin. Recently, the large-scale production of carotenoids from algal sources has gained significant interest with respect to commercial and industrial applications for health, nutrition, and cosmetic applications. Although conventional processing technologies, based on solvent extraction, offer a simple approach to isolating carotenoids, they suffer several, inherent limitations, including low efficiency (extraction yield), selectivity (purity), high solvent consumption, and long treatment times, which have led to advancements in the search for innovative extraction technologies. This comprehensive review summarizes the recent trends in the extraction of carotenoids from microalgae and seaweeds through the assistance of different innovative techniques, such as pulsed electric fields, liquid pressurization, supercritical fluids, subcritical fluids, microwaves, ultrasounds, and high-pressure homogenization. In particular, the review critically analyzes technologies, characteristics, advantages, and shortcomings of the different innovative processes, highlighting the differences in terms of yield, selectivity, and economic and environmental sustainability.

[Study on molecular recognition technology in active constituents extracted and isolated from Aconitum pendulum].

PubMed

Ma, Xue-Qin; Li, Guo-Shan; Fu, Xue-Yan; Ma, Jing-Zu

2011-03-01

To investigate CD molecular recognition technology applied in active constituents extracted and isolated from traditional Chinese medicine--Aconitum pendulum. The inclusion constant and form probability of the inclusion complex of Aconitum pendulum with p-CD was calculated by UV spectra method. The active constituents of Aconitum pendulum were extracted and isolated by molecular recognition technology. The inclusion complex was identified by UV. The chemical constituents of Aconitum pendulum and inclusion complex was determined by HPLC. The analgesic effects of inclusion complex was investigated by experiment of intraperitoneal injection of acetic acid in rats. The inclusion complex was identified and confirmed by UV spectra method, the chemical components of inclusion complex were simple, and the content of active constituents increased significantly, the analgesic effects of inclusion complex was well. The molecular recognition technology can be used for extracting and isolating active constituents of Aconitum pendulum, and the effects are obvious.

SITE TECHNOLOGY CAPSULE: IITRI RADIO FREQUENCY HEATING TECHNOLOGY

EPA Science Inventory

Radio frequency heating (RFH) technologies use electromagnetic energy in the radio frequency i(RF) band to heat soil in-situ, thereby potentially enhancing the performances of standard soil vapor extraction (SVE) technologies. ontaminants are removed from in situ soils and transf...

SITE TECHNOLOGY CAPSULE: IITRI RADIO FREQUENCY HEATING TECHNOLOGY

EPA Science Inventory

Radio frequency heating (RFH) technologies use electromagnetic energy in the radio frequency (RF) band to heat soil in situ, thereby potentially enhancing the performance of standard soil vapor extraction (SVE) technologies. Contaminants are removed from in situ soils and transfe...

[Optimization of dissolution process for superfine grinding technology on total saponins of Panax ginseng fibrous root by response surface methodology].

PubMed

Zhao, Ya; Lai, Xiao-Pin; Yao, Hai-Yan; Zhao, Ran; Wu, Yi-Na; Li, Geng

2014-03-01

To investigate the effects of superfine comminution extraction technology of ginseng total saponins from Panax ginseng fibrous root, and to make sure the optimal extraction condition. Optimal condition of ginseng total saponins from Panax ginseng fibrous root was based on single factor experiment to study the effects of crushing degree, extraction time, alcohol concentration and extraction temperature on extraction rate. Response surface method was used to investigate three main factors such as superfine comminution time, extraction time and alcohol concentration. The relationship between content of ginseng total saponins in Panax ginseng fibrous root and three factors fitted second degree polynomial models. The optimal extraction condition was 9 min of superfine comminution time, 70% of alcohol, 50 degrees C of extraction temperature and 70 min of extraction time. Under the optimal condition, ginseng total saponins from Panax ginseng fibrous root was average 94. 81%, which was consistent with the predicted value. The optimization of technology is rapid, efficient, simple and stable.

COGNIS TERRAMET® LEAD EXTRACTION PROCESS; INNOVATIVE TECHNOLOGY EVALUATION REPORT

EPA Science Inventory

This report documents an evaluation of lead removal from sands and fines fractions of contaminated soils by the COGNIS TERRAMET® lead extraction process (COGNIS process). The evaluation was performed under the U.S. Environmental Protection Agency's Superfund Innovative Technolog...

SOIL VAPOR EXTRACTION TECHNOLOGY: REFERENCE HANDBOOK

EPA Science Inventory

Soil vapor extraction (SVE) systems are being used in Increasing numbers because of the many advantages these systems hold over other soil treatment technologies. SVE systems appear to be simple in design and operation, yet the fundamentals governing subsurface vapor transport ar...

The Learning Edge: What Technology Can Do to Educate All Children. Technology, Education--Connections (TEC) Series

ERIC Educational Resources Information Center

Bain, Alan; Weston, Mark E.

2011-01-01

After billions of dollars, thousands of studies, and immeasurable effort by educators at all levels, why is the performance of students and teachers so unaffected by technology? Moreover, what should be done to extract genuine benefit from the information and communication technology (ICT) revolution? In this groundbreaking book, technology and…

Chelation technology: a promising green approach for resource management and waste minimization.

PubMed

Chauhan, Garima; Pant, K K; Nigam, K D P

2015-01-01

Green chemical engineering recognises the concept of developing innovative environmentally benign technologies to protect human health and ecosystems. In order to explore this concept for minimizing industrial waste and for reducing the environmental impact of hazardous chemicals, new greener approaches need to be adopted for the extraction of heavy metals from industrial waste. In this review, a range of conventional processes and new green approaches employed for metal extraction are discussed in brief. Chelation technology, a modern research trend, has shown its potential to develop sustainable technology for metal extraction from various metal-contaminated sites. However, the interaction mechanism of ligands with metals and the ecotoxicological risk associated with the increased bioavailability of heavy metals due to the formation of metal-chelant complexes is still not sufficiently explicated in the literature. Therefore, a need was felt to provide a comprehensive state-of-the-art review of all aspects associated with chelation technology to promote this process as a green chemical engineering approach. This article elucidates the mechanism and thermodynamics associated with metal-ligand complexation in order to have a better understanding of the metal extraction process. The effects of various process parameters on the formation and stability of complexes have been elaborately discussed with respect to optimizing the chelation efficiency. The non-biodegradable attribute of ligands is another important aspect which is currently of concern. Therefore, biotechnological approaches and computational tools have been assessed in this review to illustrate the possibility of ligand degradation, which will help the readers to look for new environmentally safe mobilizing agents. In addition, emerging trends and opportunities in the field of chelation technology have been summarized and the diverse applicability of chelation technology in metal extraction from contaminated sites has also been reviewed.

DEMONSTRATION BULLETIN: TERRA KLEEN SOLVENT EXTRACTION TECHNOLOGY - TERRA-KLEEN RESPONSE GROUP, INC.

EPA Science Inventory

The Terra-Kleen Solvent Extraction Technology was developed by Terra-Kleen Response Group, Inc., to remove polychlorinated biphenyls (PCB) and other organic constituents from contaminated soil. This batch process system uses a proprietary solvent at ambient temperatures to treat ...

Superfund Innovative Technology Evaluation: Demonstration Bulletin: Organic Extraction Utilizing Solvents

EPA Science Inventory

This technology utilizes liquified gases as the extracting solvent to remove organics, such as hydrocarbons, oil and grease, from wastewater or contaminated sludges and soils. Carbon dioxide is generally used for aqueous solutions, and propane is used for sediment, sludges and ...

Diethylstilbestrol in fish tissue determined through subcritical fluid extraction and with GC-MS

NASA Astrophysics Data System (ADS)

Qiao, Qinghui; Shi, Nianrong; Feng, Xiaomei; Lu, Jie; Han, Yuqian; Xue, Changhu

2016-06-01

As the key point in sex hormone analysis, sample pre-treatment technology has attracted scientists' attention all over the world, and the development trend of sample preparation forwarded to faster and more efficient technologies. Taking economic and environmental concerns into account, subcritical fluid extraction as a faster and more efficient method has stood out as a sample pre-treatment technology. This new extraction technology can overcome the shortcomings of supercritical fluid and achieve higher extraction efficiency at relatively low pressures and temperatures. In this experiment, a simple, sensitive and efficient method has been developed for the determination of diethylstilbestrol (DES) in fish tissue using subcritical 1,1,1,2-tetrafluoroethane (R134a) extraction in combination with gas chromatography-mass spectrometry (GC-MS). After extraction, freezing-lipid filtration was utilized to remove fatty co-extract. Further purification steps were performed with C18 and NH2 solid phase extraction (SPE). Finally, the analyte was derived by heptafluorobutyric anhydride (HFBA), followed by GC-MS analysis. Response surface methodology (RSM) was employed to optimizing the extraction condition, and the optimized was as follows: extraction pressure, 4.3 MPa; extraction temperature, 26°C; amount of co-solvent volume, 4.7 mL. Under this condition, at a spiked level of 1, 5, 10 μg kg-1, the mean recovery of DES was more than 90% with relative standard deviations (RSDs) less than 10%. Finally, the developed method has been successfully used to analyzing the real samples.

Microencapsulation by solvent extraction/evaporation: reviewing the state of the art of microsphere preparation process technology.

PubMed

Freitas, Sergio; Merkle, Hans P; Gander, Bruno

2005-02-02

The therapeutic benefit of microencapsulated drugs and vaccines brought forth the need to prepare such particles in larger quantities and in sufficient quality suitable for clinical trials and commercialisation. Very commonly, microencapsulation processes are based on the principle of so-called "solvent extraction/evaporation". While initial lab-scale experiments are frequently performed in simple beaker/stirrer setups, clinical trials and market introduction require more sophisticated technologies, allowing for economic, robust, well-controllable and aseptic production of microspheres. To this aim, various technologies have been examined for microsphere preparation, among them are static mixing, extrusion through needles, membranes and microfabricated microchannel devices, dripping using electrostatic forces and ultrasonic jet excitation. This article reviews the current state of the art in solvent extraction/evaporation-based microencapsulation technologies. Its focus is on process-related aspects, as described in the scientific and patent literature. Our findings will be outlined according to the four major substeps of microsphere preparation by solvent extraction/evaporation, namely, (i) incorporation of the bioactive compound, (ii) formation of the microdroplets, (iii) solvent removal and (iv) harvesting and drying the particles. Both, well-established and more advanced technologies will be reviewed.

[Application of micro-power system in the surgery of tooth extraction].

PubMed

Kaijin, Hu; Yongfeng, Li

2015-02-01

Tooth extraction is a common operation in oral surgery. Traditional-extraction instruments, such as bone chisel, elevator, and bone hammer, lead to not only severe trauma but also unnecessary complications, and patients easily become nervous and apprehensive if tooth extraction is performed using these violent instruments. In recent years, with the develop- ment of minimally invasive concept and technology, various micro-power instruments have been used for tooth extraction. This innovative technology can reduce the iatrogenic trauma and complications of tooth extraction. Additionally, this technology can greatly decrease the patient's physical and mental pressure. The new equipment compensates for the deficiency of traditional tooth extraction equipment and facilitates the gradual replacement of the latter. Diverse micro-power systems have distinct strengths and weaknesses, so some auxiliary instruments are still needed during tooth extraction. This paper focuses on the various micro-power systems for tooth extraction and tries to compare the advantages and disadvantages of these systems. Selection and usage of auxiliary equipment are also introduced. Thus, this paper provides reference for the proper application of the micro-power systems in tooth extraction.

SITE TECHNOLOGY CAPSULE: TERRA-KLEEN SOLVENT EXTRACTION TECHNOLOGY

EPA Science Inventory

Remediation of PCBs in soils has been difficult to implement on a full-scale, cost-effective basis. The Terra-Kleen solvent extraction system has overcome many of the soil handling, contaminant removal, and regulatory restrictions that have made it difficult to implement a cost-e...

U.S. ENVIRONMENTAL PROTECTION AGENCY'S SUPERFUND INNOVATIVE TECHNOLOGY EVALUATION OF PNEUMATIC FRACTURING EXTRACTION

EPA Science Inventory

The U.S. Environmental Protection Agency (EPA), in cooperation with Accutech Remedial Systems (ARS) and the New Jersey Institute of Technology (NJIT) performed a field demonstration of Pneumatic Fracturing Extraction (PFE) for the removal of chlorinated volatile organics (VOCS) f...

[Application of continuous mixing technology in ethanol precipitation process of Salvia miltiorrhiza by using micromixer].

PubMed

Gong, Xing-Chu; Shen, Ji-Chen; Qu, Hai-Bin

2016-12-01

Continuous pharmaceutical manufacturing is one of the development directions in international pharmaceutical technology. In this study, a continuous mixing technology of ethanol and concentrated extract in the ethanol precipitation of Salvia miltiorrhiza was realized by using a membrane dispersion method. The effects of ethanol flowrate, concentrated extract flowrate, and flowrate ratio on ethanol precipitation results were investigated. With the increase of the flowrates of ethanol and concentrated extract, retention rate of active phenolic acids components was increased, and the total solid removal rate was decreased. The purity of active components in supernatants was mainly affected by the ratio of ethanol flowrate and concentrated extract flowrate. The mixing efficiency of adding ethanol under continuous flow mixing mode in this study was comparable to that of industrial ethanol precipitation. Continuous adding ethanol by using a membrane dispersion mixer is a promising technology with many advantages such as easy enlargement, large production per unit volume, and easy control. Copyright© by the Chinese Pharmaceutical Association.

Pressure-relief and methane production performance of pressure relief gas extraction technology in the longwall mining

NASA Astrophysics Data System (ADS)

Zhang, Cun; Tu, Shihao; Chen, Min; Zhang, Lei

2017-02-01

Pressure relief gas extraction technology (PRGET) has been successfully implemented at many locations as a coal mine methane exploitation and outburst prevention technology. Comprehensive PRGET including gob gas venthole (GGV), crossing seam drilling hole (CSDH), large diameter horizontal long drilling hole (LDHLDH) and buried pipe for extraction (BPE) have been used to extract abundant pressure-relief methane (PRM) during protective coal seam mining; these techniques mitigated dangers associated with coal and gas outbursts in 13-1 coal seam mining in the Huainan coalfield. These extraction technologies can ensure safe protective seam mining and effectively extract coal and gas. This article analyses PRGET production performance and verifies it with the field measurement. The results showed that PRGET drilling to extract PRM from the protected coal seam significantly reduced methane emissions from a longwall ventilation system and produced highly efficient extraction. Material balance analyses indicated a significant decrease in gas content and pressure in the protected coal seam, from 8.78 m3 t-1 and 4.2 MPa to 2.34 m3 t-1 and 0.285 MPa, respectively. The field measurement results of the residual gas content in protected coal seam (13-1 coal seam) indicated the reliability of the material balance analyses and the pressure relief range of PRGET in the protected coal seam is obtained.

SEMINAR PROCEEDINGS: RCRA CORRECTIVE ACTION STABILIZATION TECHNOLOGIES

EPA Science Inventory

The seminar publication provides an overview of many technologies that can be used in applying the stabilization concept to RCRA cleanup activities. Technologies discussed include covers, grouting, slurry walls, hydrofracture, horizontal well drilling, a vacuum extraction, and b...

ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, PCB DETECTION TECHNOLOGY, HYBRIZYME DELFIA TM ASSAY

EPA Science Inventory

The DELFIA PCB Assay is a solid-phase time-resolved fluoroimmunoassay based on the sequential addition of sample extract and europium-labeled PCB tracer to a monoclonal antibody reagent specific for PCBs. In this assay, the antibody reagent and sample extract are added to a strip...

CONTROL TECHNOLOGY EXTRACTION OF MERCURY FROM GROUNDWATER IMMOBILIZED ALGAE

EPA Science Inventory

Bio-Recovery Systems, Inc. conducted a project under the Emerging Technology portion of the United States Environmental Protection Agency (EPAs) Superfund Innovative Technology Evaluation (SITE) Program to evaluate the ability of immobilized algae to adsorb mercury from contamina...

Extraction of latent images from printed media

NASA Astrophysics Data System (ADS)

Sergeyev, Vladislav; Fedoseev, Victor

2015-12-01

In this paper we propose an automatic technology for extraction of latent images from printed media such as documents, banknotes, financial securities, etc. This technology includes image processing by adaptively constructed Gabor filter bank for obtaining feature images, as well as subsequent stages of feature selection, grouping and multicomponent segmentation. The main advantage of the proposed technique is versatility: it allows to extract latent images made by different texture variations. Experimental results showing performance of the method over another known system for latent image extraction are given.

Concomitant Leaching and Electrochemical Extraction of Rare Earth Elements from Monazite.

PubMed

Maes, Synthia; Zhuang, Wei-Qin; Rabaey, Korneel; Alvarez-Cohen, Lisa; Hennebel, Tom

2017-02-07

Rare earth elements (REEs) have become increasingly important in modern day technologies. Unfortunately, their recycling is currently limited, and the conventional technologies for their extraction and purification are exceedingly energy and chemical intensive. New sustainable technologies for REE extraction from both primary and secondary resources would be extremely beneficial. This research investigated a two-stage recovery strategy focused on the recovery of neodymium (Nd) and lanthanum (La) from monazite ore that combines microbially based leaching (using citric acid and spent fungal supernatant) with electrochemical extraction. Pretreating the phosphate-based monazite rock (via roasting) dramatically increased the microbial REE leaching efficiency. Batch experiments demonstrated the effective and continued leaching of REEs by recycled citric acid, with up to 392 mg of Nd L -1 and 281 mg of La L -1 leached during seven consecutive 24 h cycles. Neodymium was further extracted in the catholyte of a three-compartment electrochemical system, with up to 880 mg of Nd L -1 achieved within 4 days (at 40 A m -2 ). Meanwhile, the radioactive element thorium and counterions phosphate and citrate were separated effectively from the REEs in the anolyte, favoring REE extraction and allowing sustainable reuse of the leaching agent. This study shows a promising technology that is suitable for primary ores and can further be optimized for secondary resources.

[Application of microwave technology in extraction process of Guizhi Fuling capsule].

PubMed

Wang, Zheng-kuan; Zhou, Mao; Liu, Yuan; Bi, Yu-an; Wang, Zhen-zhong; Xiao, Wei

2015-06-01

In this paper, optimization of the conditions of microwave technique in extraction process of Guizhi Fuling capsule in the condition of a pilot scale was carried out. First of all, through the single factor experiment investigation of various factors, the overall impact tendency and range of each factor were determined. Secondly, L9 (3(4)) orthogonal test optimization was used, and the contents of gallic acid in liquid, paeoniflorin, benzoic acid, cinnamic acid, benzoyl paeoniflorin, amygdalin of the liquid medicine were detected. The extraction rate and comprehensive evaluation were calculated with the extraction effect, as the judgment basis. Theoptimum extraction process of Guizhi Fuling capsule by microwave technology was as follows: the ratio of liquid to solid was 6: 1 added to drinking water, the microwave power was 6 kW, extraction time was 20 min for 3 times. The process of the three batch of amplification through verification, the results are stable, and compared with conventional water extraction has the advantages of energy saving, time saving, high efficiency advantages. The above results show the optimum extracting technology of high efficiency, stable and feasible.

IITRI RADIO FREQUENCY HEATING TECHNOLOGY - INNOVATIVE TECHNOLOGY EVALUATION REPORT

EPA Science Inventory

IITRI's patented in situ RFH technology enhances the removal of volatile and semi-volatile organics by soil vapor extraction (SVE). Electromagnetic energy heats the soil resulting in increased contaminant vapor pressures and potentially higher soil permeability. RFH heats soil us...

Separation of heavy metals: Removal from industrial wastewaters and contaminated soil

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peters, R.W.; Shem, L.

1993-01-01

This paper reviews the applicable separation technologies relating to removal of heavy metals from solution and from soils in order to present the state-of-the-art in the field. Each technology is briefly described and typical operating conditions and technology performance are presented. Technologies described include chemical precipitation (including hydroxide, carbonate, or sulfide reagents), coagulation/flocculation, ion exchange, solvent extraction, extraction with chelating agents, complexation, electrochemical operation, cementation, membrane operations, evaporation, adsorption, solidification/stabilization, and vitrification. Several case histories are described, with a focus on waste reduction techniques and remediation of lead-contaminated soils. The paper concludes with a short discussion of important research needsmore » in the field.« less

Separation of heavy metals: Removal from industrial wastewaters and contaminated soil

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peters, R.W.; Shem, L.

1993-03-01

This paper reviews the applicable separation technologies relating to removal of heavy metals from solution and from soils in order to present the state-of-the-art in the field. Each technology is briefly described and typical operating conditions and technology performance are presented. Technologies described include chemical precipitation (including hydroxide, carbonate, or sulfide reagents), coagulation/flocculation, ion exchange, solvent extraction, extraction with chelating agents, complexation, electrochemical operation, cementation, membrane operations, evaporation, adsorption, solidification/stabilization, and vitrification. Several case histories are described, with a focus on waste reduction techniques and remediation of lead-contaminated soils. The paper concludes with a short discussion of important research needsmore » in the field.« less

The extraction of bitumen from western oil sands. Annual report, July 1991--July 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oblad, A.G.; Bunger, J.W.; Dahlstrom, D.A.

1992-08-01

The University of Utah tar sand research and development program is concerned with research and development on Utah is extensive oil sands deposits. The program has been intended to develop a scientific and technological base required for eventual commercial recovery of the heavy oils from oil sands and processing these oils to produce synthetic crude oil and other products such as asphalt. The overall program is based on mining the oil sand, processing the mined sand to recover the heavy oils and upgrading them to products. Multiple deposits are being investigated since it is believed that a large scale (approximatelymore » 20,000 bbl/day) plant would require the use of resources from more than one deposit. The tasks or projects in the program are organized according to the following classification: Recovery technologies which includes thermal recovery methods, water extraction methods, and solvent extraction methods; upgrading and processing technologies which covers hydrotreating, hydrocracking, and hydropyrolysis; solvent extraction; production of specialty products; and environmental aspects of the production and processing technologies. These tasks are covered in this report.« less

SITE TECHNOLOGY CAPSULE: KAI RADIO FREQUENCY HEATING TECHNOLOGY

EPA Science Inventory

KAI developed a patented, in situ RFH technology to enhance the removal of volatile and semi-volatile organics by soil vapor extraction (SVE). Electromagnetic energy heats the soil resulting in increased contaminant vapor pressures and soil permeability that may increase with dry...

DEMONSTRATION BULLETIN: RADIO FREQUENCY HEATING - KAI TECHNOLOGIES, INC.

EPA Science Inventory

Radio frequency heating (RFH) is a process that uses electromagnetic energy in the radio frequency (RF) band to heat soil in situ, thereby potentially enhancing the performance of standard soil vapor extraction (SVE) technologies. An RFH system developed by KAI Technologies, I...

Microwave-Assisted Extraction for Microalgae: From Biofuels to Biorefinery

PubMed Central

Pandhal, Jagroop

2018-01-01

The commercial reality of bioactive compounds and oil production from microalgal species is constrained by the high cost of production. Downstream processing, which includes harvesting and extraction, can account for 70–80% of the total cost of production. Consequently, from an economic perspective extraction technologies need to be improved. Microalgal cells are difficult to disrupt due to polymers within their cell wall such as algaenan and sporopollenin. Consequently, solvents and disruption devices are required to obtain products of interest from within the cells. Conventional techniques used for cell disruption and extraction are expensive and are often hindered by low efficiencies. Microwave-assisted extraction offers a possibility for extraction of biochemical components including lipids, pigments, carbohydrates, vitamins and proteins, individually and as part of a biorefinery. Microwave technology has advanced since its use in the 1970s. It can cut down working times and result in higher yields and purity of products. In this review, the ability and challenges in using microwave technology are discussed for the extraction of bioactive products individually and as part of a biorefinery approach. PMID:29462888

[Extraction and purification technologies of total flavonoids from Aconitum tanguticum].

PubMed

Li, Yan-Rong; Yan, Li-Xin; Feng, Wei-Hong; Li, Chun; Wang, Zhi-Min

2014-04-01

To optimize the extraction and purification technologies of total flavonoids from Aconitum tanguticum whole plant. With the content of total flavonoids as index, the optimum extraction conditions for the concentration, volume of alcohol, extracting time and times were selected by orthogonal optimized; Comparing the adsorption quantity (mg/g) and resolution (%), four kinds of macroporous adsorption resins including D101, AB-8, X-5 and XAD-16 were investigated for the enrichment ability of total flavonoids from Aconitum tanguticum; Concentration and pH value of sample, sampling amount, elution solvent and loading and elution velocity for the optimum adsorption resin were determined. The content of total flavonoids in Aconitum tanguticum was about 4.39%; The optimum extraction technique was 70% alcohol reflux extraction for three times,each time for one hour, the ratio of material and liquid was 1:10 (w/v); The optimum purification technology was: using XAD-16 macroporous resin, the initial concentration of total flavonoids of Aconitum tanguticum was 8 mg/mL, the sampling amount was 112 mg/g dry resin, the pH value was 5, the loading velocity was 3 mL/min, the elution solvent was 70% ethanol and the elution velocity was 5 mL/min. Under the optimum conditions, the average content of total flavonoids was raised from 4.39% to 46.19%. The optimum extraction and purification technologies for total flavonoids of Aconitum tanguticum were suitable for industrial production for its simplicity and responsibility.

[Studies on preparative technology and quantitative determination for extracts of total saponin in roof of Panax japonicus].

PubMed

He, Yu-min; Lu, Ke-ming; Yuan, Ding; Zhang, Chang-cheng

2008-11-01

To explore the optimum extraction and purification condition of the total saponins in the root of Panax japonicus (RPJ), and establish its quality control methods. Designed L16 (4(5)) orthogonal test with the extraction rate of total saponins as index, to determine the rational extraction process, and the techniques of water-saturated n-butanol extraction and acetone precipitation were applied to purify the alcohol extract of RPJ. Total saponins were detected by spectrophotometry and its triterpenoidal sapogenin oleanolic acid detected by HPLC. The optimum conditions of total saponins from RPJ was as follows: the material was pulverized, dipped in 60% ethanol aqueous solution as extract solvent at 10 times of volume, and refluxed 3 times for 3 h each time. Extractant of water-saturated n-butanol with extraction times of 3 and precipitant of acetone with precipitation amount of 4-5 times were included in the purification process, which would obtain the quality products. The content of total saponins could reach to 83.48%, and oleanolic acid to 38.30%. The optimized preparative technology is stable, convenient and practical. The extract rate of RPJ was high and steady with this technology, which provided new evidence for industrializing production of the plant and developing new drug.

[Optimization of extraction process for tannins from Geranium orientali-tibeticum by supercritical CO2 method].

PubMed

Xie, Song; Tong, Zhi-Ping; Tan, Rui; Liu, Xiao-Zhen

2014-08-01

In order to optimize extraction process conditions of tannins from Geranium orientali-tibeticum by supercritical CO2, the content of tannins was determined by phosphomolybdium tungsten acid-casein reaction, with extraction pressure, extraction temper- ature and extraction time as factors, the content of tannins from extract of G. orientali-tibeticum as index, technology conditions were optimized by orthogonal test. Optimum technology conditions were as follows: extraction pressure was 25 MPa, extraction temperature was 50 °C, extracted 1.5 h. The content of tannins in extract was 12.91 mg x g(-1), extract rate was 3.67%. The method established could be used for assay the contents of tannin in G. orientali-tibeticum. The circulated extraction was an effective extraction process that was stable and feasible, and that provides a way of the extraction process conditions of tannin from G. orientali-tibeticum.

On the problem of zinc extraction from the slags of lead heat

NASA Astrophysics Data System (ADS)

Kozyrev, V. V.; Besser, A. D.; Paretskii, V. M.

2013-12-01

The possibilities of zinc extraction from the slags of lead heat are studied as applied to the ZAO Karat-TsM lead plant to be built for processing ore lead concentrates. The process of zinc extraction into commercial fumes using the technology of slag fuming by natural gas developed in Gintsvetmet is recommended for this purpose. Technological rules are developed for designing a commercial fuming plant, as applied to the conditions of the ZAO Karat-TsM plant.

[Optimization theory and practical application of membrane science technology based on resource of traditional Chinese medicine residue].

PubMed

Zhu, Hua-Xu; Duan, Jin-Ao; Guo, Li-Wei; Li, Bo; Lu, Jin; Tang, Yu-Ping; Pan, Lin-Mei

2014-05-01

Resource of traditional Chinese medicine residue is an inevitable choice to form new industries characterized of modem, environmental protection and intensive in the Chinese medicine industry. Based on the analysis of source and the main chemical composition of the herb residue, and for the advantages of membrane science and technology used in the pharmaceutical industry, especially membrane separation technology used in improvement technical reserves of traditional extraction and separation process in the pharmaceutical industry, it is proposed that membrane science and technology is one of the most important choices in technological design of traditional Chinese medicine resource industrialization. Traditional Chinese medicine residue is a very complex material system in composition and character, and scientific and effective "separation" process is the key areas of technology to re-use it. Integrated process can improve the productivity of the target product, enhance the purity of the product in the separation process, and solve many tasks which conventional separation is difficult to achieve. As integrated separation technology has the advantages of simplified process and reduced consumption, which are in line with the trend of the modern pharmaceutical industry, the membrane separation technology can provide a broad platform for integrated process, and membrane separation technology with its integrated technology have broad application prospects in achieving resource and industrialization process of traditional Chinese medicine residue. We discuss the principles, methods and applications practice of effective component resources in herb residue using membrane separation and integrated technology, describe the extraction, separation, concentration and purification application of membrane technology in traditional Chinese medicine residue, and systematically discourse suitability and feasibility of membrane technology in the process of traditional Chinese medicine resource industrialization in this paper.

Nurse-Technology Interactions and Patient Safety.

PubMed

Ruppel, Halley; Funk, Marjorie

2018-06-01

Nurses are the end-users of most technology in intensive care units, and the ways in which they interact with technology affect quality of care and patient safety. Nurses' interactions include the processes of ensuring proper input of data into the technology as well as extracting and interpreting the output (clinical data, technical data, alarms). Current challenges in nurse-technology interactions for physiologic monitoring include issues regarding alarm management, workflow interruptions, and monitor surveillance. Patient safety concepts, like high reliability organizations and human factors, can advance efforts to enhance nurse-technology interactions. Copyright © 2018 Elsevier Inc. All rights reserved.

Mobil lube dewaxing technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baker, C.L.; McGuiness, M.P.

1995-09-01

Currently, the lube refining industry is in a period of transition, with both hydroprocessing and catalytic dewaxing gathering momentum as replacements for solvent extraction and solvent dewaxing. In addition, lube product quality requirements have been increasing, both in the US and abroad. Mobil has developed a broad array of dewaxing catalytic technologies which can serve refiners throughout the stages of this transition. In the future, lube feedstocks which vary in source and wax content will become increasingly important, requiring an optimized system for highest performance. The Mobil Lube Dewaxing (MLDW) process is the work-horse of the catalytic dewaxing technologies, beingmore » a robust, low cost technology suitable for both solvent extracted and hydrocracked feeds. The Mobil Selective Dewaxing (MSDW) process has been recently introduced in response to the growth of hydroprocessing. MSDW requires either severely hydrotreated or hydrocracked feeds and provides improved lube yields and VI. For refiners with hydrocrackers and solvent dewaxing units, Mobil Wax Isomerization (MWI) technology can make higher VI base stocks to meet the growing demand for very high quality lube products. A review of these three technologies is presented in this paper.« less

Technological Change and Its Labor Impact in Five Energy Industries. Coal Mining/Oil and Gas Extraction/Petroleum Refining/Petroleum Pipeline Transportation/Electric and Gas Utilities.

ERIC Educational Resources Information Center

Bureau of Labor Statistics (DOL), Washington, DC.

This bulletin appraises major technological changes emerging in five American industries (coal mining, oil and gas extraction, petroleum refining, petroleum pipeline transportation, and electric and gas utilities) and discusses the impact of these changes on productivity and occupations over the next five to ten years. Its separate reports on each…

Learning the Language of Healthcare Enabling Semantic Web Technology in CHCS

DTIC Science & Technology

2013-09-01

tuples”, (subject, predicate, object), to relate data and achieve semantic interoperability . Other similar technologies exist, but their... Semantic Healthcare repository [5]. Ultimately, both of our data approaches were successful. However, our current test system is based on the CPRS demo...to extract system dependencies and workflows; to extract semantically related patient data ; and to browse patient- centric views into the system . We

Green Remediation Best Management Practices: Implementing In Situ Thermal Technologies

EPA Pesticide Factsheets

Over recent years, the use of in situ thermal technologies such as electrical resistance heating, thermal conductive heating, and steam enhanced extraction to remediate contaminated sites has notably increased.

High-volume extraction of nucleic acids by magnetic bead technology for ultrasensitive detection of bacteria in blood components.

PubMed

Störmer, Melanie; Kleesiek, Knut; Dreier, Jens

2007-01-01

Nucleic acid isolation, the most technically demanding and laborious procedure performed in molecular diagnostics, harbors the potential for improvements in automation. A recent development is the use of magnetic beads covered with nucleic acid-binding matrices. We adapted this technology with a broad-range 23S rRNA real-time reverse transcription (RT)-PCR assay for fast and sensitive detection of bacterial contamination of blood products. We investigated different protocols for an automated high-volume extraction method based on magnetic-separation technology for the extraction of bacterial nucleic acids from platelet concentrates (PCs). We added 2 model bacteria, Staphylococcus epidermidis and Escherichia coli, to a single pool of apheresis-derived, single-donor platelets and assayed the PCs by real-time RT-PCR analysis with an improved primer-probe system and locked nucleic acid technology. Co-amplification of human beta(2)-microglobulin mRNA served as an internal control (IC). We used probit analysis to calculate the minimum concentration of bacteria that would be detected with 95% confidence. For automated magnetic bead-based extraction technology with the real-time RT-PCR, the 95% detection limit was 29 x 10(3) colony-forming units (CFU)/L for S. epidermidis and 22 x 10(3) CFU/L for E. coli. No false-positive results occurred, either due to nucleic acid contamination of reagents or externally during testing of 1030 PCs. High-volume nucleic acid extraction improved the detection limit of the assay. The improvement of the primer-probe system and the integration of an IC make the RT-PCR assay appropriate for bacteria screening of platelets.

[Pilot-scale purification of lipopeptide from marine-derived Bacillus marinus].

PubMed

Gu, Kangbo; Guan, Cheng; Xu, Jiahui; Li, Shulan; Luo, Yuanchan; Shen, Guomin; Zhang, Daojing; Li, Yuanguang

2016-11-25

This research was aimed at establishing the pilot-scale purification technology of lipopeptide from marine-derived Bacillus marinus. We studied lipopeptide surfactivity interferences on scale-up unit technologies including acid precipitation, methanol extraction, solvent precipitation, salting out, extraction, silica gel column chromatography and HZ806 macroporous absorption resin column chromatography. Then, the unit technologies were combined in a certain order, to remove the impurities gradually, and to gain purified lipopeptide finally, with high recovery rate throughout the whole process. The novel pilot-scale purification technology could effectively isolate and purify lipopeptide with 87.51% to 100% purity in hectograms from 1 ton of Bacillus marinus B-9987 fermentation broth with more than 81.73% recovery rate. The first practical hectogram production of highly purified lipopeptide derived from Bacillus marinus was achieved. With this new purification method, using complex media became possible in fermentation process to reduce the fermentation cost and scale-up the purification for lipopeptide production. For practicability and economy, foaming problem resulting from massive water evaporation was avoided in this technology.

Solid-phase microextraction technology for in vitro and in vivo metabolite analysis

PubMed Central

Zhang, Qihui; Zhou, Liandi; Chen, Hua; Wang, Chong-Zhi; Xia, Zhining; Yuan, Chun-Su

2016-01-01

Analysis of endogenous metabolites in biological samples may lead to the identification of biomarkers in metabolomics studies. To achieve accurate sample analysis, a combined method of continuous quick sampling and extraction is required for online compound detection. Solid-phase microextraction (SPME) integrates sampling, extraction and concentration into a single solvent-free step for chemical analysis. SPME has a number of advantages, including simplicity, high sensitivity and a relatively non-invasive nature. In this article, we reviewed SPME technology in in vitro and in vivo analyses of metabolites after the ingestion of herbal medicines, foods and pharmaceutical agents. The metabolites of microorganisms in dietary supplements and in the gastrointestinal tract will also be examined. As a promising technology in biomedical and pharmaceutical research, SPME and its future applications will depend on advances in analytical technologies and material science. PMID:27695152

Extraction of indirectly captured information for use in a comparison of offline pH measurement technologies.

PubMed

Ritchie, Elspeth K; Martin, Elaine B; Racher, Andy; Jaques, Colin

2017-06-10

Understanding the causes of discrepancies in pH readings of a sample can allow more robust pH control strategies to be implemented. It was found that 59.4% of differences between two offline pH measurement technologies for an historical dataset lay outside an expected instrument error range of ±0.02pH. A new variable, Osmo Res , was created using multiple linear regression (MLR) to extract information indirectly captured in the recorded measurements for osmolality. Principal component analysis and time series analysis were used to validate the expansion of the historical dataset with the new variable Osmo Res . MLR was used to identify variables strongly correlated (p<0.05) with differences in pH readings by the two offline pH measurement technologies. These included concentrations of specific chemicals (e.g. glucose) and Osmo Res, indicating culture medium and bolus feed additions as possible causes of discrepancies between the offline pH measurement technologies. Temperature was also identified as statistically significant. It is suggested that this was a result of differences in pH-temperature compensations employed by the pH measurement technologies. In summary, a method for extracting indirectly captured information has been demonstrated, and it has been shown that competing pH measurement technologies were not necessarily interchangeable at the desired level of control (±0.02pH). Copyright © 2017 Elsevier B.V. All rights reserved.

Natural language processing-based COTS software and related technologies survey.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stickland, Michael G.; Conrad, Gregory N.; Eaton, Shelley M.

Natural language processing-based knowledge management software, traditionally developed for security organizations, is now becoming commercially available. An informal survey was conducted to discover and examine current NLP and related technologies and potential applications for information retrieval, information extraction, summarization, categorization, terminology management, link analysis, and visualization for possible implementation at Sandia National Laboratories. This report documents our current understanding of the technologies, lists software vendors and their products, and identifies potential applications of these technologies.

Translations on USSR Science and Technology, Physical Sciences and Technology, Number 45

DTIC Science & Technology

1978-08-14

hundred pages. [Question] In the public’s perception a cosmonaut seems to be, in terms of physical and mental fitness, something like a superman . How ...indicate how the original information was processed. Where no processing indicator is given, the information was summarized or extracted. Unfamiliar... how the original Information was processed. Where no processing indicator is given, the information was sipmarized or extracted, unfamiliar names

Low-rank coal study: national needs for resource development. Volume 3. Technology evaluation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1980-11-01

Technologies applicable to the development and use of low-rank coals are analyzed in order to identify specific needs for research, development, and demonstration (RD and D). Major sections of the report address the following technologies: extraction; transportation; preparation, handling and storage; conventional combustion and environmental control technology; gasification; liquefaction; and pyrolysis. Each of these sections contains an introduction and summary of the key issues with regard to subbituminous coal and lignite; description of all relevant technology, both existing and under development; a description of related environmental control technology; an evaluation of the effects of low-rank coal properties on the technology;more » and summaries of current commercial status of the technology and/or current RD and D projects relevant to low-rank coals.« less

Supercritical fluid technology: concepts and pharmaceutical applications.

PubMed

Deshpande, Praful Balavant; Kumar, G Aravind; Kumar, Averineni Ranjith; Shavi, Gopal Venkatesh; Karthik, Arumugam; Reddy, Meka Sreenivasa; Udupa, Nayanabhirama

2011-01-01

In light of environmental apprehension, supercritical fluid technology (SFT) exhibits excellent opportunities to accomplish key objectives in the drug delivery sector. Supercritical fluid extraction using carbon dioxide (CO(2)) has been recognized as a green technology. It is a clean and versatile solvent with gas-like diffusivity and liquid-like density in the supercritical phase, which has provided an excellent alternative to the use of chemical solvents. The present commentary provides an overview of different techniques using supercritical fluids and their future opportunity for the drug delivery industry. Some of the emerging applications of SFT in pharmaceuticals, such as particle design, drug solubilization, inclusion complex, polymer impregnation, polymorphism, drug extraction process, and analysis, are also covered in this review. The data collection methods are based on the recent literature related to drug delivery systems using SFT platforms. SFT has become a much more versatile and environmentally attractive technology that can handle a variety of complicated problems in pharmaceuticals. This cutting-edge technology is growing predominantly to surrogate conventional unit operations in relevance to the pharmaceutical production process. Supercritical fluid technology has recently drawn attention in the field of pharmaceuticals. It is a distinct conception that utilizes the solvent properties of supercritical fluids above their critical temperature and pressure, where they exhibit both liquid-like and gas-like properties, which can enable many pharmaceutical applications. For example, the liquid-like properties provide benefits in extraction processes of organic solvents or impurities, drug solubilization, and polymer plasticization, and the gas-like features facilitate mass transfer processes. It has become a much more versatile and environmentally attractive technology that can handle a variety of complicated problems in pharmaceuticals. This review is focused on different techniques that use supercritical fluids and their opportunities for the pharmaceutical sector.

Advanced-technology space station study: Summary of systems and pacing technologies

NASA Technical Reports Server (NTRS)

Butterfield, A. J.; Garn, P. A.; King, C. B.; Queijo, M. J.

1990-01-01

The principal system features defined for the Advanced Technology Space Station are summarized and the 21 pacing technologies identified during the course of the study are described. The descriptions of system configurations were extracted from four previous study reports. The technological areas focus on those systems particular to all large spacecraft which generate artificial gravity by rotation. The summary includes a listing of the functions, crew requirements and electrical power demand that led to the studied configuration. The pacing technologies include the benefits of advanced materials, in-orbit assembly requirements, stationkeeping, evaluations of electrical power generation alternates, and life support systems. The descriptions of systems show the potential for synergies and identifies the beneficial interactions that can result from technological advances.

Assessing the Engagement, Learning, and Overall Experience of Students Operating an Atomic Absorption Spectrophotometer with Remote Access Technology

ERIC Educational Resources Information Center

Erasmus, Daniel J.; Brewer, Sharon E.; Cinel, Bruno

2015-01-01

The use of internet-based technologies in the teaching of laboratories has emerged as a promising education tool. This study evaluated the effectiveness of using remote access technology to operate an atomic absorption spectrophotometer in analyzing the iron content in a crude myoglobin extract. Sixty-two students were surveyed on their level of…

Making Semantic Information Work Effectively for Degraded Environments

DTIC Science & Technology

2013-06-01

Control Research & Technology Symposium (ICCRTS) held 19-21 June, 2013 in Alexandria, VA. 14. ABSTRACT The challenges of effectively managing semantic...technologies over disadvantaged or degraded environments are numerous and complex. One of the greatest challenges is the size of raw data. Large...approach mitigates this challenge by performing data reduction through the adoption of format recognition technologies, semantic data extractions, and the

A review on green trend for oil extraction using subcritical water technology and biodiesel production.

PubMed

Abdelmoez, Weal; Ashour, Eman; Naguib, Shahenaz M

2015-01-01

It became a global agenda to develop clean alternative fuels which were domestically available, environmentally acceptable and technically feasible. Thus, biodiesel was destined to make a substantial contribution to the future energy demands of the domestic and industrial economies. Utilization of the non edible vegetable oils as raw materials for biodiesel production had been handled frequently for the past few years. The oil content of these seeds could be extracted by different oil extraction methods, such as mechanical extraction, solvent extraction and by subcritical water extraction technology SWT. Among them, SWT represents a new promising green extraction method. Therefore this review covered the current used non edible oil seeds for biodiesel production as well as giving a sharp focus on the efficiency of using the SWT as a promising extraction method. In addition the advantages and the disadvantages of the different biodiesel production techniques would be covered.

Model-Based Extracted Water Desalination System for Carbon Sequestration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dees, Elizabeth M.; Moore, David Roger; Li, Li

Over the last 1.5 years, GE Global Research and Pennsylvania State University defined a model-based, scalable, and multi-stage extracted water desalination system that yields clean water, concentrated brine, and, optionally, salt. The team explored saline brines that ranged across the expected range for extracted water for carbon sequestration reservoirs (40,000 up to 220,000 ppm total dissolved solids, TDS). In addition, the validated the system performance at pilot scale with field-sourced water using GE’s pre-pilot and lab facilities. This project encompassed four principal tasks, in addition to Project Management and Planning: 1) identify a deep saline formation carbon sequestration site andmore » a partner that are suitable for supplying extracted water; 2) conduct a techno-economic assessment and down-selection of pre-treatment and desalination technologies to identify a cost-effective system for extracted water recovery; 3) validate the downselected processes at the lab/pre-pilot scale; and 4) define the scope of the pilot desalination project. Highlights from each task are described below: Deep saline formation characterization The deep saline formations associated with the five DOE NETL 1260 Phase 1 projects were characterized with respect to their mineralogy and formation water composition. Sources of high TDS feed water other than extracted water were explored for high TDS desalination applications, including unconventional oil and gas and seawater reverse osmosis concentrate. Technoeconomic analysis of desalination technologies Techno-economic evaluations of alternate brine concentration technologies, including humidification-dehumidification (HDH), membrane distillation (MD), forward osmosis (FO), turboexpander-freeze, solvent extraction and high pressure reverse osmosis (HPRO), were conducted. These technologies were evaluated against conventional falling film-mechanical vapor recompression (FF-MVR) as a baseline desalination process. Furthermore, a quality function deployment (QFD) method was used to compare alternate high TDS desalination technologies to FF-MVR. High pressure reverse osmosis was found to a be a promising alternative desalination technology. A deep-dive technoeconomic analysis of HPRO was performed, including Capex and Opex estimates, for seawater RO (SWRO). Additionally, two additional cases were explored: 1) a comparison of a SWRO plus HPRO system to the option of doubling the size of a standard seawater RO system to achieve the same total pure water recovery rate; and 2) a flue gas desulfurization wastewater treatment zero-liquid discharge (ZLD) application, where preconcentration with RO (SWRO or SWRO + HPRO) before evaporation and crystallization was compared to FF-MVR and crystallization technologies without RO preconcentration. Pre-pilot process validation Pre-pilot-scale tests were conducted using field production water to validate key process steps for extracted water pretreatment. Approximately 5,000 gallons of field produced water was processed through, microfiltration, ultrafiltration, and steam regenerable sorbent operations. Smaller quantities were processed through microclarification. In addition, analytical methods (purge-and-trap gas chromatography and Hach TOC analytical methods) were validated. Lab-scale HPRO elements were constructed and tested at high pressures, to identify and mitigate technical risks of the technology. Lastly, improvements in RO membrane materials were identified as the necessary next step to achieve further improvement in element performance at high pressure. Scope of Field Pilot A field pilot for extracted water pretreatment was designed.« less

New technology of extracting the amount of rare earth metals from the red mud

NASA Astrophysics Data System (ADS)

Martoyan, G. A.; Karamyan, G. G.; Vardan, G. A.

2016-01-01

The paper outlined the environmental and economic problems associated with red mud - the waste generated in processing of bauxite ore for aluminum production. The chemical analysis of red mud has identified a number of useful elements including rare earth metals. The electromembrane technology of red mud processing with extraction of valuable elements is described. A possible scheme of separation of these metals through electrolysis is also given.

Electric field-based technologies for valorization of bioresources.

PubMed

Rocha, Cristina M R; Genisheva, Zlatina; Ferreira-Santos, Pedro; Rodrigues, Rui; Vicente, António A; Teixeira, José A; Pereira, Ricardo N

2018-04-01

This review provides an overview of recent research on electrotechnologies applied to the valorization of bioresources. Following a comprehensive summary of the current status of the application of well-known electric-based processing technologies, such as pulsed electric fields (PEF) and high voltage electrical discharges (HVED), the application of moderate electric fields (MEF) as an extraction or valorization technology will be considered in detail. MEF, known by its improved energy efficiency and claimed electroporation effects (allowing enhanced extraction yields), may also originate high heating rates - ohmic heating (OH) effect - allowing thermal stabilization of waste stream for other added-value applications. MEF is a simple technology that mostly makes use of green solvents (mainly water) and that can be used on functionalization of compounds of biological origin broadening their application range. The substantial increase of MEF-based plants installed in industries worldwide suggests its straightforward application for waste recovery. Copyright © 2018 Elsevier Ltd. All rights reserved.

The application of UV multispectral technology in extract trace evdidence

NASA Astrophysics Data System (ADS)

Guo, Jingjing; Xu, Xiaojing; Li, Zhihui; Xu, Lei; Xie, Lanchi

2015-11-01

Multispectral imaging is becoming more and more important in the field of examination of material evidence, especially the ultraviolet spectral imaging. Fingerprints development, questioned document detection, trace evidence examination-all can used of it. This paper introduce a UV multispectral equipment which was developed by BITU & IFSC, it can extract trace evidence-extract fingerprints. The result showed that this technology can develop latent sweat-sebum mixed fingerprint on photo and ID card blood fingerprint on steel hold. We used the UV spectrum data analysis system to make the UV spectral image clear to identify and analyse.

Cost studies of thermally enhanced in situ soil remediation technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bremser, J.; Booth, S.R.

1996-05-01

This report describes five thermally enhanced technologies that may be used to remediate contaminated soil and water resources. The standard methods of treating these contaminated areas are Soil Vapor Extraction (SVE), Excavate & Treat (E&T), and Pump & Treat (P&T). Depending on the conditions at a given site, one or more of these conventional alternatives may be employed; however, several new thermally enhanced technologies for soil decontamination are emerging. These technologies are still in demonstration programs which generally are showing great success at achieving the expected remediation results. The cost savings reported in this work assume that the technologies willmore » ultimately perform as anticipated by their developers in a normal environmental restoration work environment. The five technologies analyzed in this report are Low Frequency Heating (LF or Ohmic, both 3 and 6 phase AC), Dynamic Underground Stripping (DUS), Radio Frequency Heating (RF), Radio Frequency Heating using Dipole Antennae (RFD), and Thermally Enhanced Vapor Extraction System (TEVES). In all of these technologies the introduction of heat to the formation raises vapor pressures accelerating contaminant evaporation rates and increases soil permeability raising diffusion rates of contaminants. The physical process enhancements resulting from temperature elevations permit a greater percentage of volatile organic compound (VOC) or semi- volatile organic compound (SVOC) contaminants to be driven out of the soils for treatment or capture in a much shorter time period. This report presents the results of cost-comparative studies between these new thermally enhanced technologies and the conventional technologies, as applied to five specific scenarios.« less

Basewide Groundwater Operable Unit. Groundwater Operable Unit Remedial Investigation/Feasibility Study Report. Volume 3

DTIC Science & Technology

1994-06-01

technologies were organized into five categories: * In Situ Biological Treatment * In Situ Physical/Chemical Treatment * Ex Situ Biological Groundwater...Technology FIGURE 11-3 PRIMARY SCORING SUMMARY EX SITU BIOLOGICAL GROUNDWATER TREATMENT TECHNOLOGIES GROUNDWATER OPERABLE UNIT RIIFS McCLELLAN AIR FORCE... Biological Treatment CometabolicAnaerobic Anaerobic/Aerobic In Situ Physical/Chemical Treatment Sparging/Soil Vapor Extraction Ex Situ Biological

[Studies on technology of supercritical-CO2 fluid extraction for volatile oils and saikosaponins in Bupleurum chinense DC].

PubMed

Ge, F H; Li, Y; Xie, J M; Li, Q; Ma, G J; Chen, Y H; Lin, Y C; Li, X F

2000-03-01

To study the technology of supercritical-CO2 fluid extraction (SFE-CO2) for the volatile oils and saikosaponins in Bupleurum chinense. Exploring the effects of pressure, temperature, extraction time, flow rate of CO2 and entrainers on the yield of the oils and saikosaponin-contained extracts; determining the optimum conditions for SFE-CO2; analyzing the oils by GC/MS and comparing the technology of SFE-CO2 with that of traditional steam distillation. The optimum extraction conditions turned out to be--for volatile oils: pressure (EP) = 20 MPa, temperature (ET) = 30 degrees C, isolator I pressure (1P-I) = 12 MPa, temperature(1T-I) = 65 degrees C, isolator II pressure (1P-II) = 6 MPa, temperature (1T-II) = 40 degrees C, extraction time = 4 hours, and CO2 flow rate = 10-20 kg.(h.kg)-1 crude drug; for saikosaponins: EP = 30 MPa, ET = 65 degrees C, 1P I = 12 MPa, 1T I = 55 degrees C, 1P II = 6 MPa, 1T II = 43 degrees C, extraction time = 3 hours, entrainer = 60% ethanol, and CO2 flow rate = 20-25 kg.(h.kg)-1 crude drug. SFE-CO2 excels the traditional steam distillation in raising yield and reducing extraction time. The oils are composed of 22 constituents including caproaldehyde, and the saikosaponins can only be extracted with the help of entrainers under higher pressure and temperature.

Subcritical Water Technology for Enhanced Extraction of Biochemical Compounds from Chlorella vulgaris

PubMed Central

Awaluddin, S. A.; Thiruvenkadam, Selvakumar; Izhar, Shamsul; Hiroyuki, Yoshida; Danquah, Michael K.; Harun, Razif

2016-01-01

Subcritical water extraction (SWE) technology has been used for the extraction of active compounds from different biomass materials with low process cost, mild operating conditions, short process times, and environmental sustainability. With the limited application of the technology to microalgal biomass, this work investigates parametrically the potential of subcritical water for high-yield extraction of biochemicals such as carbohydrates and proteins from microalgal biomass. The SWE process was optimized using central composite design (CCD) under varying process conditions of temperature (180–374°C), extraction time (1–20 min), biomass particulate size (38–250 μm), and microalgal biomass loading (5–40 wt.%). Chlorella vulgaris used in this study shows high volatile matter (83.5 wt.%) and carbon content (47.11 wt.%), giving advantage as a feedstock for biofuel production. The results showed maximum total carbohydrate content and protein yields of 14.2 g/100 g and 31.2 g/100 g, respectively, achieved under the process conditions of 277°C, 5% of microalgal biomass loading, and 5 min extraction time. Statistical analysis revealed that, of all the parameters investigated, temperature is the most critical during SWE of microalgal biomass for protein and carbohydrate production. PMID:27366748

IPAT: a freely accessible software tool for analyzing multiple patent documents with inbuilt landscape visualizer.

PubMed

Ajay, Dara; Gangwal, Rahul P; Sangamwar, Abhay T

2015-01-01

Intelligent Patent Analysis Tool (IPAT) is an online data retrieval tool, operated based on text mining algorithm to extract specific patent information in a predetermined pattern into an Excel sheet. The software is designed and developed to retrieve and analyze technology information from multiple patent documents and generate various patent landscape graphs and charts. The software is C# coded in visual studio 2010, which extracts the publicly available patent information from the web pages like Google Patent and simultaneously study the various technology trends based on user-defined parameters. In other words, IPAT combined with the manual categorization will act as an excellent technology assessment tool in competitive intelligence and due diligence for predicting the future R&D forecast.

Effective removal of co-purified inhibitors from extracted DNA samples using synchronous coefficient of drag alteration (SCODA) technology.

PubMed

Schmedes, Sarah; Marshall, Pamela; King, Jonathan L; Budowle, Bruce

2013-07-01

Various types of biological samples present challenges for extraction of DNA suitable for subsequent molecular analyses. Commonly used extraction methods, such as silica membrane columns and phenol-chloroform, while highly successful may still fail to provide a sufficiently pure DNA extract with some samples. Synchronous coefficient of drag alteration (SCODA), implemented in Boreal Genomics' Aurora Nucleic Acid Extraction System (Boreal Genomics, Vancouver, BC), is a new technology that offers the potential to remove inhibitors effectively while simultaneously concentrating DNA. In this initial study, SCODA was tested for its ability to remove various concentrations of forensically and medically relevant polymerase chain reaction (PCR) inhibitors naturally found in tissue, hair, blood, plant, and soil samples. SCODA was used to purify and concentrate DNA from intentionally contaminated DNA samples containing known concentrations of hematin, humic acid, melanin, and tannic acid. The internal positive control (IPC) provided in the Quantifiler™ Human DNA Quantification Kit (Life Technologies, Foster City, CA) and short tandem repeat (STR) profiling (AmpFℓSTR® Identifiler® Plus PCR Amplification Kit; Life Technologies, Foster City, CA) were used to measure inhibition effects and hence purification. SCODA methodology yielded overall higher efficiency of purification of highly contaminated samples compared with the QIAquick® PCR Purification Kit (Qiagen, Valencia, CA). SCODA-purified DNA yielded no cycle shift of the IPC for each sample and yielded greater allele percentage recovery and relative fluorescence unit values compared with the QIAquick® purification method. The Aurora provided an automated, minimal-step approach to successfully remove inhibitors and concentrate DNA from challenged samples.

[Microcrystalline cellulose and their flow -- morphological properties modifications as an effective excpients in tablet formulation technology containing lattice established API and also dry plant extract].

PubMed

Zgoda, Marian Mikołaj; Nachajski, Michał Jakub; Kołodziejczyk, Michał Krzysztof

2009-01-01

The production technology of powder cellulose (Arbocel) and microcrystaline cellulose (Vivapur) and their application in the composition of direct compression tablet mass was provided. The function of silicified microcrystaline cellulose type Prosolv in the direct compression process of dry plant extract was discussed. An analysis of the chemical structure of cellulose fiber (Vitacel) enabled determining its properties and applications in the manufacture of diet supplement, pharmaceutical and food products.

A moving baseline for evaluation of advanced coal extraction systems

NASA Technical Reports Server (NTRS)

Bickerton, C. R.; Westerfield, M. D.

1981-01-01

Results from the initial effort to establish baseline economic performance comparators for a program whose intent is to define, develop, and demonstrate advanced systems suitable for coal resource extraction beyond the year 2000 are reported. Systems used were selected from contemporary coal mining technology and from conservation conjectures of year 2000 technology. The analysis was also based on a seam thickness of 6 ft. Therefore, the results are specific to the study systems and the selected seam extended to other seam thicknesses.

Vaporization or Chemical Reaction: Which controls the fate of contaminants treated by in situ thermal remediation?

EPA Science Inventory

Thermal remediation technologies, which includes steam enhanced extraction, electrical resistance heating, and thermal conductive heating, have been developed based on technologies employed by the enhanced oil recovery industry. Although mobilization and/or volatilization of con...

In Situ Biodegradation of MTBE and TBA

EPA Science Inventory

Ground water at most UST spills sites in Kansas contains both MTBE and benzene, and both contaminants must be effectively treated to close the sites. Soil vacuum extraction, and air sparging are common treatment technologies in Kansas. The technologies supply oxygen to support ...

Scan Line Based Road Marking Extraction from Mobile LiDAR Point Clouds.

PubMed

Yan, Li; Liu, Hua; Tan, Junxiang; Li, Zan; Xie, Hong; Chen, Changjun

2016-06-17

Mobile Mapping Technology (MMT) is one of the most important 3D spatial data acquisition technologies. The state-of-the-art mobile mapping systems, equipped with laser scanners and named Mobile LiDAR Scanning (MLS) systems, have been widely used in a variety of areas, especially in road mapping and road inventory. With the commercialization of Advanced Driving Assistance Systems (ADASs) and self-driving technology, there will be a great demand for lane-level detailed 3D maps, and MLS is the most promising technology to generate such lane-level detailed 3D maps. Road markings and road edges are necessary information in creating such lane-level detailed 3D maps. This paper proposes a scan line based method to extract road markings from mobile LiDAR point clouds in three steps: (1) preprocessing; (2) road points extraction; (3) road markings extraction and refinement. In preprocessing step, the isolated LiDAR points in the air are removed from the LiDAR point clouds and the point clouds are organized into scan lines. In the road points extraction step, seed road points are first extracted by Height Difference (HD) between trajectory data and road surface, then full road points are extracted from the point clouds by moving least squares line fitting. In the road markings extraction and refinement step, the intensity values of road points in a scan line are first smoothed by a dynamic window median filter to suppress intensity noises, then road markings are extracted by Edge Detection and Edge Constraint (EDEC) method, and the Fake Road Marking Points (FRMPs) are eliminated from the detected road markings by segment and dimensionality feature-based refinement. The performance of the proposed method is evaluated by three data samples and the experiment results indicate that road points are well extracted from MLS data and road markings are well extracted from road points by the applied method. A quantitative study shows that the proposed method achieves an average completeness, correctness, and F-measure of 0.96, 0.93, and 0.94, respectively. The time complexity analysis shows that the scan line based road markings extraction method proposed in this paper provides a promising alternative for offline road markings extraction from MLS data.

Scan Line Based Road Marking Extraction from Mobile LiDAR Point Clouds†

PubMed Central

Yan, Li; Liu, Hua; Tan, Junxiang; Li, Zan; Xie, Hong; Chen, Changjun

2016-01-01

Mobile Mapping Technology (MMT) is one of the most important 3D spatial data acquisition technologies. The state-of-the-art mobile mapping systems, equipped with laser scanners and named Mobile LiDAR Scanning (MLS) systems, have been widely used in a variety of areas, especially in road mapping and road inventory. With the commercialization of Advanced Driving Assistance Systems (ADASs) and self-driving technology, there will be a great demand for lane-level detailed 3D maps, and MLS is the most promising technology to generate such lane-level detailed 3D maps. Road markings and road edges are necessary information in creating such lane-level detailed 3D maps. This paper proposes a scan line based method to extract road markings from mobile LiDAR point clouds in three steps: (1) preprocessing; (2) road points extraction; (3) road markings extraction and refinement. In preprocessing step, the isolated LiDAR points in the air are removed from the LiDAR point clouds and the point clouds are organized into scan lines. In the road points extraction step, seed road points are first extracted by Height Difference (HD) between trajectory data and road surface, then full road points are extracted from the point clouds by moving least squares line fitting. In the road markings extraction and refinement step, the intensity values of road points in a scan line are first smoothed by a dynamic window median filter to suppress intensity noises, then road markings are extracted by Edge Detection and Edge Constraint (EDEC) method, and the Fake Road Marking Points (FRMPs) are eliminated from the detected road markings by segment and dimensionality feature-based refinement. The performance of the proposed method is evaluated by three data samples and the experiment results indicate that road points are well extracted from MLS data and road markings are well extracted from road points by the applied method. A quantitative study shows that the proposed method achieves an average completeness, correctness, and F-measure of 0.96, 0.93, and 0.94, respectively. The time complexity analysis shows that the scan line based road markings extraction method proposed in this paper provides a promising alternative for offline road markings extraction from MLS data. PMID:27322279

Efficient extraction strategies of tea (Camellia sinensis) biomolecules.

PubMed

Banerjee, Satarupa; Chatterjee, Jyotirmoy

2015-06-01

Tea is a popular daily beverage worldwide. Modulation and modifications of its basic components like catechins, alkaloids, proteins and carbohydrate during fermentation or extraction process changes organoleptic, gustatory and medicinal properties of tea. Through these processes increase or decrease in yield of desired components are evident. Considering the varied impacts of parameters in tea production, storage and processes that affect the yield, extraction of tea biomolecules at optimized condition is thought to be challenging. Implementation of technological advancements in green chemistry approaches can minimize the deviation retaining maximum qualitative properties in environment friendly way. Existed extraction processes with optimization parameters of tea have been discussed in this paper including its prospects and limitations. This exhaustive review of various extraction parameters, decaffeination process of tea and large scale cost effective isolation of tea components with aid of modern technology can assist people to choose extraction condition of tea according to necessity.

Authoritative knowledge, the technological imperative and women's responses to prenatal diagnostic technologies.

PubMed

McCoyd, Judith L M

2010-12-01

Theories about authoritative knowledge (AK) and the technological imperative have received varying levels of interest in anthropological, feminist and science and technology studies. Although the anthropological literature abounds with empirical considerations of authoritative knowledge, few have considered both theories through an empirical, inductive lens. Data extracted from an earlier study of 30 women's responses to termination for fetal anomaly are reanalyzed to consider the women's views of, and responses to, prenatal diagnostic technologies (PNDTs). Findings indicate that a small minority embrace the societal portrayal of technology as univalently positive, while the majority have nuanced and ambivalent responses to the use of PNDTs. Further, the interface of authoritative knowledge and the technological imperative suggests that AK derives not only from medical provider status and technology use, but also from the adequacy and trustworthiness of the information. The issue of timing and uncertainty of the information also are interrogated for their impact on women's lives and what that can illuminate about the theories of AK and the technological imperative.

An Integrative Review of Technology to Support Communication With Parents of Infants in the NICU

PubMed Central

Epstein, Elizabeth G.; Arechiga, Jaqueline; Dancy, Margaret; Simon, Jordan; Wilson, Daniel; Alhusen, Jeanne L.

2017-01-01

Objective To synthesize findings from the published literature on the use of technology in the NICU to improve communications and interactions among health care providers, parents, and infants. Data Sources Electronic databases including Ovid MEDLINE, CINAHL, Web of Science, and Google Scholar were searched for related research published through May 2016. The reference lists of all studies were reviewed, and a hand search of key journals was also conducted to locate eligible studies. Study Selection Eleven studies (five quantitative, two qualitative, and four mixed methods) were identified that met the inclusion criteria. Only studies published in English were included. Data Extraction Whittemore and Knafl’s methodology for conducting integrative reviews was used to guide data extraction, analysis, and synthesis. Data were extracted and organized according to the following headings: author, year, and location; study purpose and design; sample size and demographics; technology used; study findings; and limitations. Data Synthesis Various technologies were used, including videoconferencing, videophone, and commercially available modalities such as Skype, FaceTime, AngelEye, and NICView Webcams. In the 11 studies, three main outcomes were evaluated: parents’ perception of technology use, health care providers’ perceptions of technology use, and objective outcomes, such as parental anxiety or stress or infant length of stay. Overall, parents and health care providers perceived the varied interventions quite favorably, although a few significant differences were found for the objective measures. Conclusion Several interventions have been tested to improve communications and promote interactions among NICU health care team members, parents, and infants. Although initial findings are positive, research in this area is quite limited, and the reviewed studies had several limitations. There is a significant need for further rigorous research to be conducted with diverse samples. PMID:28263727

[Study on the extraction technology and hypoglycemic activity of lectin from Trichosanthes kirilowi].

PubMed

Li, Qiong; Ye, Xiao-Li; Zeng, Hong; Chen, Xin; Li, Xue-Gang

2012-03-01

To extract lectins from Trichosanthes kirilowi and study their hypoglycemic activity. The optimal extraction process included the following parameters were conformed by optimization analysis,lectins extracted from Trichosanthes kirilowi was achieved by ammonium sulfate precipitation; The agglutinate activity was determined by using the agglutination test with 5% human blood cells. Human hepatocarcinoma cell HepG2 and the alloxan-induced diabetic mice model were used to assess hypoglycemic activity of Lectin in Trichosanthes kirilowi. The agglutination indexes of lectins extraction buffer were 32; The cell and mice tests indicated that the lectins exhibited hypoglycemic activity in the 70% saturation. The optimum extraction technology is as follows: extraction with PBS, the material-water ratio is 1:30, the extraction time is 24 h, while the concentration of sodium chloride is 0 mol/L and pH is 7.2. Precipitate lectins by ammonium sulfate in the 70% saturation, centrifugal speed is 10 000 tracted from Trichosanthes kirilowi exposes proper hypoglycemic activity.

Role of modifier in microwave assisted extraction of oleanolic acid from Gymnema sylvestre: application of green extraction technology for botanicals.

PubMed

Mandal, Vivekananda; Dewanjee, Saikat; Mandal, Subhash C

2009-08-01

This work highlights the development of a green extraction technology for botanicals with the use of microwave energy. Taking into consideration the extensive time involved in conventional extraction methods, coupled with usage of large volumes of organic solvent and energy resources, an ecofriendly green method that can overcome the above problems has been developed. The work compares the effect of sample pretreatment with untreated sample for improved yield of oleanolic acid from Gymnema sylvestre leaves. The pretreated sample with water produced 0.71% w/w oleanolic acid in one extraction cycle with 500 W microwave power, 25 mL methanol and only an 8 min extraction time. On the other hand, a conventional heat reflux extraction for 6 hours could produce only 0.62% w/w oleanolic acid. The detailed mechanism of extraction has been studied through scanning electron micrographs. The environmental impact of the proposed green method has also been evaluated.

SOLUBILIZATION AND MICROEMULSIFICATION OF CHLORINATED SOLVENTS USING DIRECT FOOD ADDITIVE (EDIBLE) SURFACTANTS (JOURNAL)

EPA Science Inventory

Surfactant enhanced subsurface remediation is being evaluated as an innovative technology to expedite contaminant extraction from the subsurface. Regulatory approval of this technology will likely be enhanced by use of surfactants with FDA direct food additive status ("edible" su...

Liquid fossil-fuel technology. Quarterly technical progress report, April-June 1982

DOE Office of Scientific and Technical Information (OSTI.GOV)

Linville, B.

This report primarily covers in-house oil, gas, and synfuel research and lists the contracted research. The report is broken into the following areas: liquid fossil fuel cycle, extraction, processing, utilization, and project integration and technology transfer. BETC publications are listed. (DLC)

Typical Applications of Airborne LIDAR Technolagy in Geological Investigation

NASA Astrophysics Data System (ADS)

Zheng, X.; Xiao, C.

2018-05-01

The technology of airborne light detection and ranging (LiDAR), also referred to as Airborne Laser Scanning, is widely used for high-resolution topographic data acquisition (even under forest cover) with sub-meter planimetric and vertical accuracy. This contribution constructs the real digital terrain model to provide the direct observation data for the landscape analysis in geological domains. Based on the advantage of LiDAR, the authors mainly deal with the applications of LiDAR data to such fields as surface land collapse, landslide and fault structure extraction. The review conclusion shows that airborne LiDAR technology is becoming an indispensable tool for above mentioned issues, especially in the local and large scale investigations of micro-topography. The technology not only can identify the surface collapse, landslide boundary and subtle faulted landform, but also be able to extract the filling parameters of collapsed surface, the geomorphic parameters of landslide stability evaluation and cracks. This technology has extensive prospect of applications in geological investigation.

Effect of sludge features and extraction-esterification technology on the synthesis of biodiesel from secondary wastewater treatment sludges.

PubMed

Patiño, Yolanda; Mantecón, Laura G; Polo, Sara; Faba, Laura; Díaz, Eva; Ordóñez, Salvador

2018-01-01

Secondary sludge from municipal wastewater treatment plant is proposed as a promising alternative lipid feedstock for biodiesel production. A deep study combining different type of raw materials (sludge coming from the oxic, anoxic and anaerobic steps of the biological treatment) with different technologies (liquid-liquid and solid-liquid extractions followed by acid catalysed transesterification and in situ extraction-transesterification procedure) allows a complete comparison of available technologies. Different parameters - contact time, catalyst concentration, pretreatments - were considered, obtaining more than 17% FAMEs yield after 50min of sonication with the in situ procedure and 5% of H 2 SO 4 . This result corresponds to an increment of more than 65% respect to the best results reported at typical conditions. Experimental data were used to propose a mathematical model for this process, demonstrating that the mass transfer of lipids from the sludge to the liquid is the limiting step. Copyright © 2017 Elsevier Ltd. All rights reserved.

DEMETERRES project: development of innovative technologies for removing radionuclides from contaminated solid and liquid matrices

NASA Astrophysics Data System (ADS)

Chagvardieff, Pierre; Barré, Yves; Blin, Virginie; Faure, Sylvain; Fornier, Anne; Grange, Didier; Grandjean, Agnès; Guiderdoni, Emmanuel; Henner, Pascale; Siroux, Brice; Leybros, Antoine; Messalier, Marc; Paillard, Hervé; Prévost, Thierry; Rennesson, Malvina; Sarrobert, Catherine; Vavasseur, Alain; Véry, Anne-Aliénor

2017-09-01

As part of the « post-accidental » management, the DEMETERRES project (RSNR PIA) proposes to develop innovative and environmentally friendly methods for removal of cesium and strontium from soils and liquid matrices in order to rehabilitate them for an agricultural use while minimizing the volume of generated wastes in accordance with the nuclear waste existing processes. Complementary approaches are used: they are based on physico-chemical technologies (such as foams flotation, supercritical CO2 extraction, extractants in fluidized bed reactor …) and biological ones (bioextractants, phytoextraction) which concepts are described. These researches aim to design innovative and performing extractants in term of selectivity and to achieve the pilot reactor phase for each of them. These pilots will group in a network to provide a technological platform lasting the project, to which will be attached an available network of experts. The respective advances of these researches are presented, completed of tests initiated in Japan on contaminated soils through partnerships.

New solid-state chemistry technologies to bring better drugs to market: knowledge-based decision making.

PubMed

Park, Aeri; Chyall, Leonard J; Dunlap, Jeanette; Schertz, Christine; Jonaitis, David; Stahly, Barbara C; Bates, Simon; Shipplett, Rex; Childs, Scott

2007-01-01

Modern drug development demands constant deployment of more effective technologies to mitigate the high cost of bringing new drugs to market. In addition to cost savings, new technologies can improve all aspects of pharmaceutical development. New technologies developed at SSCI, Inc. include solid form development of an active pharmaceutical ingredients. (APIs) are PatternMatch software and capillary-based crystallisation techniques that not only allow for fast and effective solid form screening, but also extract maximum property information from the routine screening data that is generally available. These new technologies offer knowledge-based decision making during solid form development of APIs and result in more developable API solid forms.

Aquantis C-Plane Ocean Current Turbine Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fleming, Alex

The Aquantis 2.5 MW Ocean Current Generation Device technology developed by Dehlsen Associates, LLC (DA) is a derivation of wind power generating technology (a means of harnessing a slow moving fluid) adapted to the ocean environment. The Aquantis Project provides an opportunity for accelerated technological development and early commercialization, since it involves the joining of two mature disciplines: ocean engineering and wind turbine design. The Aquantis Current Plane (C-Plane) technology is an ocean current turbine designed to extract kinetic energy from a current flow. The technology is capable of achieving competitively priced, continuous, base-load, and reliable power generation from amore » source of renewable energy not before possible in this scale or form.« less

[Studies on technology optimization for extraction and purification of total flavones from root bark of Artocarpus styracifolius].

PubMed

Ren, Gang; Liu, Rong-hua; Shao, Feng; Huang, Hui-lian; Wen, Li-rong

2010-08-01

To study the technology optimization for extraction and purification of total flavones from root bark of Artocarpus styracifolius. The optimum extraction conditions were investigated by the contents of the total flavones, using orthogonal test; Static adsorption capacity and desorption rate were employed as examine items for the screening of optimum macroporous resin and optimum technology for the purification of total flavones with selected macroporous were also investigated. The optimum extraction conditions were as follows: using 60% alcohol of seven times than amounts of original material soaking 12 hours,extracting once with hot reflux method at 50 degrees C. HPD-500 type macroporous resin showed better adsorption and desorption property. The optimum purification conditions were as follows: the sample solution was prepared at the concentration of 50.0 mg/mL, subjected to HPD-500 type macroporous resin column chromatography with a load ratio of 22.0 mg total flavones per gram of resin. After standing for 1 hour, the column was eluted with 4 BV water before being eluted with 4 BV 80% alcohol. The purity of the product was 86.4%, which enhanced the content of total flavones by 533%. The optimum conditions for extraction and purification of total flavones from root bark of Artocarpus styractifolius are convenient and practical, and could be used as a reference for industrial production.

Assessing the engagement, learning, and overall experience of students operating an atomic absorption spectrophotometer with remote access technology.

PubMed

Erasmus, Daniel J; Brewer, Sharon E; Cinel, Bruno

2015-01-01

The use of internet-based technologies in the teaching of laboratories has emerged as a promising education tool. This study evaluated the effectiveness of using remote access technology to operate an atomic absorption spectrophotometer in analyzing the iron content in a crude myoglobin extract. Sixty-two students were surveyed on their level of engagement, learning, and overall experience. Feedback from students suggests that the use of remote access technology is effective in teaching students the principles of chemical analysis by atomic absorption spectroscopy. © 2014 The International Union of Biochemistry and Molecular Biology.

On the Development of Hydrogen Isotope Extraction Technologies for a Full LiMIT-Style PFC Liquid Lithium Loop

NASA Astrophysics Data System (ADS)

Christenson, Michael; Szott, Matthew; Stemmley, Steven; Mettler, Jeremy; Wendeborn, John; Moynihan, Cody; Ahn, Chisung; Andruczyk, Daniel; Ruzic, David

2017-10-01

Lithium has proven over numerous studies to improve core confinement, allowing access to operational regimes previously unattainable when using solid, high-Z divertor and limiter modules in magnetic confinement devices. Lithium readily absorbs fuel species, and while this is advantageous, it is also detrimental with regards to tritium inventory and safety concerns. As such, extraction technologies for the recovery of hydrogenic isotopes captured by lithium require development and testing in the context of a larger lithium loop recycling system. Proposed reclamation technologies at the University of Illinois at Urbana-Champaign (UIUC) will take advantage of the thermophysical properties of the lithium-hydrogen-lithium hydride system as the driving force for recovery. Previous work done at UIUC indicates that hydrogen release from pure lithium hydride reaches a maximum of 7 x 1018 s-1 at 665 °C. While this recovery rate is appreciable, reactor-scale scenarios will require isotope recycling to happen on an even faster timescale. The ratio of isotope dissolution to hydride precipitate formation must therefore be determined, along with the energy needed to recoup trapped hydrogen isotopes. Extraction technologies for use with a LiMIT-style loop system will be discussed and results will be presented. DOE/ALPS DE-FG02-99ER54515.

Comparison of end-of-life tire treatment technologies: a Chinese case study.

PubMed

Li, Xingfu; Xu, He; Gao, Yingnan; Tao, Yijun

2010-11-01

The aim of this paper is to compare different end-of-life tire (ELT) treatment technologies in China from an environmental and economic perspective. Four treatment technologies were evaluated: ambient grinding, devulcanization, pyrolysis and illegal tire oil extraction. Life cycle assessment (LCA) was applied to evaluate the potential environmental impact of each treatment based on the Eco-indicator 99 (Hierarchist approach) method provided by GaBi 4 software. The final result shows that pyrolysis represents the environmentally benign option while illegal tire oil extraction caused the worst damages. For the three legal treatments, although high credit was obtained when considering avoided impacts from recycled materials and energy, they have great impact as to respiratory effects (inorganic) dominantly contributed by energy production stage, which implies that the emphasis on environmental policies related to ELT treatment should shift from the control of emissions from treatment process to the reduction of energy consumption. A simplified comparison of net benefits and total impacts shows that the most eco-effective ELT treatment technology is pyrolysis, followed by dynamic devulcanization and ambient grinding. The illegal tire oil extraction, however, must be prohibited immediately because of its highest environmental pollution and lowest net benefit. Copyright © 2010 Elsevier Ltd. All rights reserved.

SITE TECHNOLOGY CAPSULE: IN SITU STEAM ENHANCED RECOVERY PROCESS

EPA Science Inventory

The SERP technology is designed to treat soils contaminated with VOCs and SVOCs in situ. Steam injection and vacuum extraction are used to remove the organic compounds from the soil and concentrate them for disposal or recycling. A full-scale demonstration of SERP was conducted a...

CLEANING EXCAVATED SOIL USING EXTRACTION AGENTS: A STATE-OF-THE-ART REVIEW

EPA Science Inventory

This report presents a state-of-the-art review of soil washing technologies and their applicability to Superfund sites in the United States. The review includes Superfund site soil and contamination characteristics; as well as soil cleaning technologies, their principles of opera...

IMPACT OF COSOLVENT FLUSHING ON SUBSURFACE MICROBIAL ECOLOGY AT A FORMER DRY CLEANER SITE

EPA Science Inventory

The Solvent Extraction Residual Biotreatment (SERB) technology was evaluated at a former dry cleaner site in Jacksonville, FL where an area of tetrachloroethene (PCE) contamination was identified. The SERB technology is a treatment train approach to complete site restoration, wh...

IMPACT OF COSOLVENT FLUSHING ON SUBSURFACE MICROBIAL ECOLOGY AT THE FORMER SAGE'S DRY CLEANER SITE

EPA Science Inventory

The Solvent Extraction Residual Biotreatment (SERB) technology was evaluated at the former Sage's Dry Cleaner site in Jacksonville, FL where an area of tetrachloroethylene (PCE) contamination was identified. The SERB technology is a treatment train approach to complete site rest...

[Study on the extraction of the total alkaloids from Caulopyhllum robustum].

PubMed

Li, Yi-ping; Yang, Guang-de; He, Lang-chong

2007-02-01

To study the technological parameters of the extraction process of the total alkaloids from Caulopyhllum robstum. Taspine, whiVh is main component of the total alkaloids from Caulopyhllum robustum, was selected as an evaluating marker and determined by HPLC. The orthogonal test was used to optimize extracting conditions in the process of acid water extraction. Then the optimized conditions for purification using cation exchange resin were investigated. The optimized conditions in the process of acid water extraction were 1% hydrochloric acid as much as seven times of the medicine amount for 24hs and three times. Then the extraction of acid water was purified with a column of macroporous cation exchange resin LSD001 at 2 ml/min of flow rate, then eluted with 10BV of 4% aqueous ammonia ethanol. The extraction ratio of the total alkaloids was 1. 35% and the content of taspine of the total alkaloids was 6. 80%. This technology is simply, cheap effective and feasible for manufacture in great scale.

Multiple Solvent Extraction System with Flow Injection Technology.

DTIC Science & Technology

1981-09-30

encounters a back extraction step where the direction of the extraction is from organic to aqueous solvent. Thus it is advantageous to incorporate both...stainless steel ( Alltech Associates, Arlington Heights, IQ) and prepared from a single section of 180 cmn in length. The Section 2 mixing and extraction

Life-Cycle environmental impact assessment of mineral industries

NASA Astrophysics Data System (ADS)

Hisan Farjana, Shahjadi; Huda, Nazmul; Parvez Mahmud, M. A.

2018-05-01

Mining is the extraction and processing of valuable ferro and non-ferro metals and minerals to be further used in manufacturing industries. Valuable metals and minerals are extracted from the geological deposits and ores deep in the surface through complex manufacturing technologies. The extraction and processing of mining industries involve particle emission to air or water, toxicity to the environment, contamination of water resources, ozone layer depletion and most importantly decay of human health. Despite all these negative impacts towards sustainability, mining industries are working throughout the world to facilitate the employment sector, economy and technological growth. The five most important miners in the world are South Africa, Russia, Australia, Ukraine, Guinea. The mining industries contributes to their GDP significantly. However, the most important issue is making the mining world sustainable thus reducing the emissions. To address the environmental impacts caused by the mining sectors, this paper is going to analyse the environmental impacts caused by the 5 major minerals extraction processes, which are bauxite, ilmenite, iron ore, rutile and uranium by using the life-cycle impact assessment technologies. The analysis is done here using SimaPro software version 8.4 using ReCipe, CML and Australian indicator method.

Subcritical Water Technology for Extraction of Phenolic Compounds from Chlorella sp. Microalgae and Assessment on Its Antioxidant Activity.

PubMed

Zakaria, Siti Maisurah; Kamal, Siti Mazlina Mustapa; Harun, Mohd Razif; Omar, Rozita; Siajam, Shamsul Izhar

2017-07-03

Chlorella sp . microalgae is a potential source of antioxidants and natural bioactive compounds used in the food and pharmaceutical industries. In this study, a subcritical water (SW) technology was applied to determine the phenolic content and antioxidant activity of Chlorella sp . This study focused on maximizing the recovery of Chlorella sp. phenolic content and antioxidant activity measured by 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay as a function of extraction temperature (100-250 °C), time (5-20 min) and microalgae concentration (5-20 wt. %) using response surface methodology. The optimal operating conditions for the extraction process were found to be 5 min at 163 °C with 20 wt. % microalgae concentration, which resulted in products with 58.73 mg gallic acid equivalent (GAE)/g phenolic content and 68.5% inhibition of the DPPH radical. Under optimized conditions, the experimental values were in close agreement with values predicted by the model. The phenolic content was highly correlated (R² = 0.935) with the antioxidant capacity. Results indicated that extraction by SW technology was effective and that Chlorella sp . could be a useful source of natural antioxidants.

The change in critical technologies for computational physics

NASA Technical Reports Server (NTRS)

Watson, Val

1990-01-01

It is noted that the types of technology required for computational physics are changing as the field matures. Emphasis has shifted from computer technology to algorithm technology and, finally, to visual analysis technology as areas of critical research for this field. High-performance graphical workstations tied to a supercommunicator with high-speed communications along with the development of especially tailored visualization software has enabled analysis of highly complex fluid-dynamics simulations. Particular reference is made here to the development of visual analysis tools at NASA's Numerical Aerodynamics Simulation Facility. The next technology which this field requires is one that would eliminate visual clutter by extracting key features of simulations of physics and technology in order to create displays that clearly portray these key features. Research in the tuning of visual displays to human cognitive abilities is proposed. The immediate transfer of technology to all levels of computers, specifically the inclusion of visualization primitives in basic software developments for all work stations and PCs, is recommended.

Proceedings of the twenty sixth international symposium on discharges and electrical insulation in vacuum. V. 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

2014-07-01

Vacuum science and technology has made vital contributions in high technology areas like space, high energy particle accelerators, plasma devices, pulse power, electronics, vacuum interrupters, thin films, melting and refining of metals/alloys, extraction and processing of advanced materials. Vacuum discharges, vacuum arc physics and technology and various applications towards vacuum interrupters, pulse power and particle accelerator are the main themes for this symposium. Papers relevant to INIS are indexed separately.

Proceedings of the twenty sixth international symposium on discharges and electrical insulation in vacuum. V. 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

2014-07-01

Vacuum science and technology has made vital contributions in high technology areas like space, high energy particle accelerators, plasma devices, pulse power, electronics, vacuum interrupters, thin films, melting and refining of metals/alloys, extraction and processing of advanced materials. Vacuum discharges, vacuum arc physics and technology and various applications towards vacuum interrupters, pulse power and particle accelerator are the main themes for this symposium. Papers relevant to INIS are indexed separately.

National Alliance for Advanced Biofuels and Bio-Products Final Technical Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Olivares, Jose A.; Baxter, Ivan; Brown, Judith

2014-09-30

The main objective of NAABB was to combine science, technology, and engineering expertise from across the nation to break down critical technical barriers to commercialization of algae-based biofuels. The approach was to address technology development across the entire value chain of algal biofuels production, from selection of strains to cultivation, harvesting, extraction, fuel conversion, and agricultural coproduct production. Sustainable practices and financial feasibility assessments ununderscored the approach and drove the technology development.

Application of Magnetic Nanoparticles in Pretreatment Device for POPs Analysis in Water

NASA Astrophysics Data System (ADS)

Chu, Dongzhi; Kong, Xiangfeng; Wu, Bingwei; Fan, Pingping; Cao, Xuan; Zhang, Ting

2018-01-01

In order to reduce process time and labour force of POPs pretreatment, and solve the problem that extraction column was easily clogged, the paper proposed a new technology of extraction and enrichment which used magnetic nanoparticles. Automatic pretreatment system had automatic sampling unit, extraction enrichment unit and elution enrichment unit. The paper briefly introduced the preparation technology of magnetic nanoparticles, and detailly introduced the structure and control system of automatic pretreatment system. The result of magnetic nanoparticles mass recovery experiments showed that the system had POPs analysis preprocessing capability, and the recovery rate of magnetic nanoparticles were over 70%. In conclusion, the author proposed three points optimization recommendation.

The role of water in unconventional in situ energy resource extraction technologies: Chapter 7 in Food, energy, and water: The chemistry connection

USGS Publications Warehouse

Gallegos, Tanya J.; Bern, Carleton R.; Birdwell, Justin E.; Haines, Seth S.; Engle, Mark A.

2015-01-01

Global trends toward developing new energy resources from lower grade, larger tonnage deposits that are not generally accessible using “conventional” extraction methods involve variations of subsurface in situ extraction techniques including in situ oil-shale retorting, hydraulic fracturing of petroleum reservoirs, and in situ recovery (ISR) of uranium. Although these methods are economically feasible and perhaps result in a smaller above-ground land-use footprint, there remain uncertainties regarding potential subsurface impacts to groundwater. This chapter provides an overview of the role of water in these technologies and the opportunities and challenges for water reuse and recycling.

Linear feature extraction from radar imagery: SBIR (Small Business Innovative Research), phase 2, option 2

NASA Astrophysics Data System (ADS)

Milgram, David L.; Kahn, Philip; Conner, Gary D.; Lawton, Daryl T.

1988-12-01

The goal of this effort is to develop and demonstrate prototype processing capabilities for a knowledge-based system to automatically extract and analyze features from Synthetic Aperture Radar (SAR) imagery. This effort constitutes Phase 2 funding through the Defense Small Business Innovative Research (SBIR) Program. Previous work examined the feasibility of and technology issues involved in the development of an automated linear feature extraction system. This final report documents this examination and the technologies involved in automating this image understanding task. In particular, it reports on a major software delivery containing an image processing algorithmic base, a perceptual structures manipulation package, a preliminary hypothesis management framework and an enhanced user interface.

Ontology Extraction Tools: An Empirical Study with Educators

ERIC Educational Resources Information Center

Hatala, M.; Gasevic, D.; Siadaty, M.; Jovanovic, J.; Torniai, C.

2012-01-01

Recent research in Technology-Enhanced Learning (TEL) demonstrated several important benefits that semantic technologies can bring to the TEL domain. An underlying assumption for most of these research efforts is the existence of a domain ontology. The second unspoken assumption follows that educators will build domain ontologies for their…

Energy, environmental and climate assessment with the EPA MARKAL energy system modeling framework

EPA Science Inventory

The energy system is comprised of the technologies and fuels that extend from the import or extraction of energy resources (e.g., mines and wells), through the conversion of these resources into useful forms (e.g., electricity and gasoline), to the technologies (e.g., cars, light...

Current Educational Technology Research Trends in Japan

ERIC Educational Resources Information Center

Nakayama, Minoru; Ueno, Maomi

2009-01-01

To examine trends in educational practice research, this article conducted a survey and analysis of factors affecting the review of research papers in the field of the educational technology in Japan. Two factors, namely, practical orientation and theoretical orientation, were extracted from 63 survey responses, and scores from members of a…

EMERGING TECHNOLOGY BULLETIN: PROCESS FOR THE TREATMENT OF VOLATILE ORGANIC CARBON AND HEAVY-METAL- CONTAMINATED SOIL - INTERNATIONAL TECHNOLOGY CORPORATION

EPA Science Inventory

The batch steam distillation and metal extraction treatment process is a two-stage system that treats soils contaminated with organics and inorganics. This system uses conventional, readily available process equipment, and does not produce hazardous combustion products. Hazar...

Hydrometallurgical methods of recovery of scandium from the wastes of various technologies

NASA Astrophysics Data System (ADS)

Molchanova, T. V.; Akimova, I. D.; Smirnov, K. M.; Krylova, O. K.; Zharova, E. V.

2017-03-01

The recovery of scandium from the wastes of the production of uranium, titanium, iron-vanadium, and alumina is studied. The applied acid schemes of scandium transfer to a solution followed by ion-exchange recovery and extraction concentration of scandium ensure the precipitation of crude scandium oxides containing up to 5% Sc2O3. Scandium oxides of 99.96-99.99% purity are formed after additional refining of these crude oxides according to an extraction technology using a mixture 15% multiradical phosphine oxide or Cyanex-925 + 15% tributyl phosphate in kerosene.

A Review of Vapor Extraction Technology for Contaminated Soil Remediation

DTIC Science & Technology

1993-05-01

NUMBER DATE DTIC ACCESSION 23 MAY 94 NOTICE 1 . REPORT IDENTIFYING INFORMATION I. PU yurmiWin av W A. ORIGINATING anENCY m of ftm...NUMBER W 6 to8 8t. N00123-89-G-0531 2. DISTRIBUTION STATEMENT MTIr" 1 . Aswa AD Nuntw. ŕPPROVED FOR PUPLIC t•ELSASE; 2. ,elumtom ust,. DIST, Ri?-"jTO...8217 ,10" ’J’) ZL DTIC Form 50 PREVIOUS EDITIONS ARE OBSOLETE DEC 91 ,/ / 1 . - ’ < > i•" 1 A REVIEW OF VAPOR EXTRACTION TECHNOLOGY FOR CONTAMINATED SOIL

Benchmarks of a III-V TFET technology platform against the 10-nm CMOS FinFET technology node considering basic arithmetic circuits

NASA Astrophysics Data System (ADS)

Strangio, S.; Palestri, P.; Lanuzza, M.; Esseni, D.; Crupi, F.; Selmi, L.

2017-02-01

In this work, a benchmark for low-power digital applications of a III-V TFET technology platform against a conventional CMOS FinFET technology node is proposed. The analysis focuses on full-adder circuits, which are commonly identified as representative of the digital logic environment. 28T and 24T topologies, implemented in complementary-logic and transmission-gate logic, respectively, are investigated. Transient simulations are performed with a purpose-built test-bench on each single-bit full adder solution. The extracted delays and energy characteristics are post-processed and translated into figures-of-merit for multi-bit ripple-carry-adders. Trends related to the different full-adder implementations (for the same device technology platform) and to the different technology platforms (for the same full-adder topology) are presented and discussed.

The Future Potential of Wave Power in the US

NASA Astrophysics Data System (ADS)

Previsic, M.; Epler, J.; Hand, M.; Heimiller, D.; Short, W.; Eurek, K.

2012-12-01

The theoretical ocean wave energy resource potential exceeds 50% of the annual domestic energy demand of the US, is located in close proximity of coastal population centers, and, although variable in nature, may be more consistent and predictable than some other renewable generation technologies. As renewable electricity generation technologies, ocean wave energy offers a low air pollutant option for diversifying the US electricity generation portfolio. Furthermore, the output characteristics of these technologies may complement other renewable technologies. This study addresses: (1) The energy extraction potential from the US wave energy resource, (2) The present cost of wave technology in /kW, (3) The estimated cost of energy in /kWh, and (4) Cost levels at which the technology should see significant deployment. RE Vision Consulting in collaboration with NREL engaged in various analyses to establish present-day and future cost profiles for MHK technologies, compiled existing resource assessments and wave energy supply curves, and developed cost and deployment scenarios using the ReEDS analysis model to estimate the present-day technology cost reductions necessary to facilitate significant technology deployment in the US.

Greener approach for the extraction of copper metal from electronic waste.

PubMed

Jadhao, Prashant; Chauhan, Garima; Pant, K K; Nigam, K D P

2016-11-01

Technology innovations resulted into a major move from agricultural to industrial economy in last few decades. Consequently, generation of waste electronic and electrical equipments (WEEE) has been increased at a significant rate. WEEE contain large amount of precious and heavy metals and therefore, can be considered a potential secondary resource to overcome the scarcity of metals. Also, presence of these metals may affect the ecosystem due to lack of adequate management of WEEE. Building upon our previous experimental investigations for metal extraction from spent catalyst, present study explores the concept of green technology for WEEE management. Efforts have been made to recover base metal from a printed circuit board using eco-friendly chelation technology and results were compared with the conventional acid leaching method. 83.8% recovery of copper metal was achieved using chelation technology whereas only 27% could be recovered using acid leaching method in absence of any oxidant at optimum reaction conditions. Various characterization studies (energy dispersive X-ray analysis, scanning electron microscopy, X-ray diffraction, inductive coupled plasma spectrophotometry) of Printed Circuit Board (PCB) and residues were performed for qualitative and quantitative analysis of samples. Significant metal extraction, more than 96% recovery of chelating agent, recycling of reactant in next chelation cycle and nearly zero discharge to the environment are the major advantages of the proposed green process which articulate the transcendency of chelation technology over other conventional approaches. Kinetic investigation suggests diffusion controlled process as the rate determining step for the chelate assisted recovery of copper from WEEE with activation energy of 22kJ/mol. Copyright © 2015 Elsevier Ltd. All rights reserved.

Measurement of glucose area under the curve using minimally invasive interstitial fluid extraction technology: evaluation of glucose monitoring concepts without blood sampling.

PubMed

Sato, Toshiyuki; Okada, Seiki; Hagino, Kei; Asakura, Yoshihiro; Kikkawa, Yasuo; Kojima, Junko; Watanabe, Toshihiro; Maekawa, Yasunori; Isobe, Kazuki; Koike, Reona; Nakajima, Hiromu; Asano, Kaoru

2011-12-01

Monitoring postprandial hyperglycemia is crucial in treating diabetes, although its dynamics make accurate monitoring difficult. We developed a new technology for monitoring postprandial hyperglycemia using interstitial fluid (ISF) extraction technology without blood sampling. The glucose area under the curve (AUC) using this system was measured as accumulated ISF glucose (IG) with simultaneous calibration with sodium ions. The objective of this study was to evaluate this technological concept in healthy individuals. Minimally invasive ISF extraction technology (MIET) comprises two steps: pretreatment with microneedles and ISF accumulation over a specific time by contact with a solvent. The correlation between glucose and sodium ion levels using MIET was evaluated in 12 subjects with stable blood glucose (BG) levels during fasting. BG and IG time courses were evaluated in three subjects to confirm their relationship while BG was fluctuating. Furthermore, the accuracy of glucose AUC measurements by MIET was evaluated several hours after a meal in 30 subjects. A high correlation was observed between glucose and sodium ion levels when BG levels were stable (R=0.87), indicating that sodium ion is a good internal standard for calibration. The variation in IG and BG with MIET was similar, indicating that IG is an adequate substitute for BG. Finally, we showed a strong correlation (R=0.92) between IG-AUC and BG-AUC after a meal. These findings validate the adequacy of glucose AUC measurements using MIET. Monitoring glucose using MIET without blood sampling may be beneficial to patients with diabetes.

The research of road and vehicle information extraction algorithm based on high resolution remote sensing image

NASA Astrophysics Data System (ADS)

Zhou, Tingting; Gu, Lingjia; Ren, Ruizhi; Cao, Qiong

2016-09-01

With the rapid development of remote sensing technology, the spatial resolution and temporal resolution of satellite imagery also have a huge increase. Meanwhile, High-spatial-resolution images are becoming increasingly popular for commercial applications. The remote sensing image technology has broad application prospects in intelligent traffic. Compared with traditional traffic information collection methods, vehicle information extraction using high-resolution remote sensing image has the advantages of high resolution and wide coverage. This has great guiding significance to urban planning, transportation management, travel route choice and so on. Firstly, this paper preprocessed the acquired high-resolution multi-spectral and panchromatic remote sensing images. After that, on the one hand, in order to get the optimal thresholding for image segmentation, histogram equalization and linear enhancement technologies were applied into the preprocessing results. On the other hand, considering distribution characteristics of road, the normalized difference vegetation index (NDVI) and normalized difference water index (NDWI) were used to suppress water and vegetation information of preprocessing results. Then, the above two processing result were combined. Finally, the geometric characteristics were used to completed road information extraction. The road vector extracted was used to limit the target vehicle area. Target vehicle extraction was divided into bright vehicles extraction and dark vehicles extraction. Eventually, the extraction results of the two kinds of vehicles were combined to get the final results. The experiment results demonstrated that the proposed algorithm has a high precision for the vehicle information extraction for different high resolution remote sensing images. Among these results, the average fault detection rate was about 5.36%, the average residual rate was about 13.60% and the average accuracy was approximately 91.26%.

Review of NASA programs in applying aerospace technology to energy

NASA Technical Reports Server (NTRS)

Schwenk, F. C.

1981-01-01

NASA's role in energy research and development, with the aid of aerospace technology, is reviewed. A brief history, which began in 1974 with studies of solar energy systems on earth, is presented, and the major energy programs, consisting of over 60 different projects, are described, and include solar terrestrial systems, conservation and fossil energy systems, and space utilization systems. Special attention is given to the Satellite Power System and the isolation of nuclear wastes in space. Emerging prospects for NASA programs in energy technology include bioenergy, and ocean thermal energy conversion, coal extraction and conversion technologies, and support to the nuclear industry in power plant systems safety.

An extension of fracture mechanics/technology to larger and smaller cracks/defects

PubMed Central

Abé, Hiroyuki

2009-01-01

Fracture mechanics/technology is a key science and technology for the design and integrity assessment of the engineering structures. However, the conventional fracture mechanics has mostly targeted a limited size of cracks/defects, say of from several hundred microns to several tens of centimeters. The author and his group has tried to extend that limited size and establish a new version of fracture technology for very large cracks used in geothermal energy extraction and for very small cracks/defects or damage often appearing in the combination of mechanical and electronic components of engineering structures. Those new versions are reviewed in this paper. PMID:19907123

An extension of fracture mechanics/technology to larger and smaller cracks/defects.

PubMed

Abé, Hiroyuki

2009-01-01

Fracture mechanics/technology is a key science and technology for the design and integrity assessment of the engineering structures. However, the conventional fracture mechanics has mostly targeted a limited size of cracks/defects, say of from several hundred microns to several tens of centimeters. The author and his group has tried to extend that limited size and establish a new version of fracture technology for very large cracks used in geothermal energy extraction and for very small cracks/defects or damage often appearing in the combination of mechanical and electronic components of engineering structures. Those new versions are reviewed in this paper.

Model-based Extracted Water Desalination System for Carbon Sequestration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gettings, Rachel; Dees, Elizabeth

The focus of this research effort centered around water recovery from high Total Dissolved Solids (TDS) extracted waters (180,000 mg/L) using a combination of water recovery (partial desalination) technologies. The research goals of this project were as follows: 1. Define the scope and test location for pilot-scale implementation of the desalination system, 2.Define a scalable, multi-stage extracted water desalination system that yields clean water, concentrated brine, and, salt from saline brines, and 3. Validate overall system performance with field-sourced water using GE pre-pilot lab facilities. Conventional falling film-mechanical vapor recompression (FF-MVR) technology was established as a baseline desalination process. Amore » quality function deployment (QFD) method was used to compare alternate high TDS desalination technologies to the base case FF-MVR technology, including but not limited to: membrane distillation (MD), forward osmosis (FO), and high pressure reverse osmosis (HPRO). Technoeconomic analysis of high pressure reverse osmosis (HPRO) was performed comparing the following two cases: 1. a hybrid seawater RO (SWRO) plus HPRO system and 2. 2x standard seawater RO system, to achieve the same total pure water recovery rate. Pre-pilot-scale tests were conducted using field production water to validate key process steps for extracted water pretreatment. Approximately 5,000 gallons of field produced water was processed through, microfiltration, ultrafiltration, and steam regenerable sorbent operations. Improvements in membrane materials of construction were considered as necessary next steps to achieving further improvement in element performance at high pressure. Several modifications showed promising results in their ability to withstand close to 5,000 PSI without gross failure.« less

Fundus Image Features Extraction for Exudate Mining in Coordination with Content Based Image Retrieval: A Study

NASA Astrophysics Data System (ADS)

Gururaj, C.; Jayadevappa, D.; Tunga, Satish

2018-02-01

Medical field has seen a phenomenal improvement over the previous years. The invention of computers with appropriate increase in the processing and internet speed has changed the face of the medical technology. However there is still scope for improvement of the technologies in use today. One of the many such technologies of medical aid is the detection of afflictions of the eye. Although a repertoire of research has been accomplished in this field, most of them fail to address how to take the detection forward to a stage where it will be beneficial to the society at large. An automated system that can predict the current medical condition of a patient after taking the fundus image of his eye is yet to see the light of the day. Such a system is explored in this paper by summarizing a number of techniques for fundus image features extraction, predominantly hard exudate mining, coupled with Content Based Image Retrieval to develop an automation tool. The knowledge of the same would bring about worthy changes in the domain of exudates extraction of the eye. This is essential in cases where the patients may not have access to the best of technologies. This paper attempts at a comprehensive summary of the techniques for Content Based Image Retrieval (CBIR) or fundus features image extraction, and few choice methods of both, and an exploration which aims to find ways to combine these two attractive features, and combine them so that it is beneficial to all.

Fundus Image Features Extraction for Exudate Mining in Coordination with Content Based Image Retrieval: A Study

NASA Astrophysics Data System (ADS)

Gururaj, C.; Jayadevappa, D.; Tunga, Satish

2018-06-01

Medical field has seen a phenomenal improvement over the previous years. The invention of computers with appropriate increase in the processing and internet speed has changed the face of the medical technology. However there is still scope for improvement of the technologies in use today. One of the many such technologies of medical aid is the detection of afflictions of the eye. Although a repertoire of research has been accomplished in this field, most of them fail to address how to take the detection forward to a stage where it will be beneficial to the society at large. An automated system that can predict the current medical condition of a patient after taking the fundus image of his eye is yet to see the light of the day. Such a system is explored in this paper by summarizing a number of techniques for fundus image features extraction, predominantly hard exudate mining, coupled with Content Based Image Retrieval to develop an automation tool. The knowledge of the same would bring about worthy changes in the domain of exudates extraction of the eye. This is essential in cases where the patients may not have access to the best of technologies. This paper attempts at a comprehensive summary of the techniques for Content Based Image Retrieval (CBIR) or fundus features image extraction, and few choice methods of both, and an exploration which aims to find ways to combine these two attractive features, and combine them so that it is beneficial to all.

Current technologies and new insights for the recovery of high valuable compounds from fruits by-products.

PubMed

Ferrentino, Giovanna; Asaduzzaman, Md; Scampicchio, Matteo Mario

2018-02-11

The recovery of high valuable compounds from food waste is becoming a tighten issue in food processing. The large amount of non-edible residues produced by food industries causes pollution, difficulties in the management, and economic loss. The waste produced during the transformation of fruits includes a huge amount of materials such as peels, seeds, and bagasse, whose disposal usually represents a problem. Research over the past 20 years revealed that many food wastes could serve as a source of potentially valuable bioactive compounds, such as antioxidants and vitamins with increasing scientific interest thanks to their beneficial effects on human health. The challenge for the recovery of these compounds is to find the most appropriate and environment friendly extraction technique able to achieve the maximum extraction yield without compromising the stability of the extracted products. Based on this scenario, the aim of the current review is twofold. The first is to give a brief overview of the most important bioactive compounds occurring in fruit wastes. The second is to describe the pro and cons of the most up-to-dated innovative and environment friendly extraction technologies that can be an alternative to the classical solvent extraction procedures for the recovery of valuable compounds from fruit processing. Furthermore, a final section will take into account published findings on the combination of some of these technologies to increase the extracts yields of bioactives.

An innovative ultrasound assisted extraction micro-scale cell combined with gas chromatography/mass spectrometry in negative chemical ionization to determine persistent organic pollutants in air particulate matter.

PubMed

Beristain-Montiel, E; Villalobos-Pietrini, R; Arias-Loaiza, G E; Gómez-Arroyo, S L; Amador-Muñoz, O

2016-12-16

New clean technologies are needed to determine concentration of organic pollutants without generating more pollution. A method to extract Persistent Organic Pollutants (POPs) from airborne particulate matter was developed using a novel technology recently patented called ultrasound assisted extraction micro-scale cell (UAE-MSC). This technology extracts, filters, collects the sample, and evaporates the solvent, on-line. No sample transfer is needed. The cell minimizes sample manipulation, solvent consumption, waste generation, time, and energy; fulfilling most of the analytical green chemistry protocol. The methodology was optimized applying a centred 2 3 factorial experimental design. Optimum conditions were used to validate and determine concentration of 16 organochlorine pesticides (OCls) and 6 polybrominated diphenyl ethers (PBDEs). The best conditions achieved were 2 extractions with 5mL (each) of dichloromethane over 5min (each) at 60°C and 80% ultrasound potency. POPs were determined by gas chromatography/mass spectrometry in negative chemical ionization (GC/MS-NCI). Analytical method validation was carried out on airborne particles spiked with POPs at seven concentration levels between 0.5 and 26.9pgm -3 . This procedure was done by triplicate (N=21). Recovery, ranged between 65.5±2.3% and 107.5±3.0% for OCls and between 79.1±6.5% and 105.2±3.8% for PBDEs. Linearity (r 2 ) was ≥0.94 for all compounds. Method detection limits, ranged from 0.5 to 2.7pgm -3 , while limits of quantification (LOQ), ranged from 1.7 to 9.0pgm -3 . A Bias from -18.6% to 9% for PBDEs was observed in the Standard Reference Material (SRM) 2787. SRM 2787 did not contain OCls. OCls recoveries were equivalent by UAE-MSC and Soxhlet methods UAE-MSC optimized extraction conditions reduced 30 times less solvent and decreased the extraction time from several hours to ten minutes, respect to Soxhlet. UAE-MSC was applied to 15 samples of particles less than 2.5μm (PM 2.5 ) from three seasons (warm dry, rainy, and cold dry) collected in five sites around Mexico City. OCls (4,4'-DDE and endrin aldehyde) concentrations ranged from

Membrane contactor assisted extraction/reaction process employing ionic liquids

DOEpatents

Lin, Yupo J [Naperville, IL; Snyder, Seth W [Lincolnwood, IL

2012-02-07

The present invention relates to a functionalized membrane contactor extraction/reaction system and method for extracting target species from multi-phase solutions utilizing ionic liquids. One preferred embodiment of the invented method and system relates to an extraction/reaction system wherein the ionic liquid extraction solutions act as both extraction solutions and reaction mediums, and allow simultaneous separation/reactions not possible with prior art technology.

Effect of Rehabilitation Technology Services on Vocational Rehabilitation Outcomes of Individuals with Multiple Sclerosis

ERIC Educational Resources Information Center

Chiu, Chung-Yi; Tansey, Timothy N.; Chan, Fong; Strauser, David; Frain, Michael P.; Arora, Simran

2015-01-01

Objectives: To examine the effect of rehabilitation technology interventions on the employment or job retention outcomes of individuals with multiple sclerosis (MS) served by the state-federal vocational rehabilitation program using a case-control study design. Participants: Data for this study were extracted from the Rehabilitation Services…

Space technology in the discovery and development of mineral and energy resources

NASA Technical Reports Server (NTRS)

Lowman, P. D.

1977-01-01

Space technology, applied to the discovery and extraction of mineral and energy resources, is summarized. Orbital remote sensing for geological purposes has been widely applied through the use of LANDSAT satellites. These techniques also have been of value for protection against environmental hazards and for a better understanding of crustal structure.

PERFORMANCE OF CONVENTIONAL REMEDIAL TECHNOLOGY FOR TREATMENT OF MTBE AND BENZENE AT UST SITES IN KANSAS

EPA Science Inventory

Ground water at most UST spills sites in Kansas contains both MTBE and benzene, and both contaminants must be effectively treated to close the sites. Soil vacuum extraction, air sparging, and excavation are the most common treatment technologies in Kansas. To compare the relati...

Research on Crowdsourcing Emergency Information Extraction of Based on Events' Frame

NASA Astrophysics Data System (ADS)

Yang, Bo; Wang, Jizhou; Ma, Weijun; Mao, Xi

2018-01-01

At present, the common information extraction method cannot extract the structured emergency event information accurately; the general information retrieval tool cannot completely identify the emergency geographic information; these ways also do not have an accurate assessment of these results of distilling. So, this paper proposes an emergency information collection technology based on event framework. This technique is to solve the problem of emergency information picking. It mainly includes emergency information extraction model (EIEM), complete address recognition method (CARM) and the accuracy evaluation model of emergency information (AEMEI). EIEM can be structured to extract emergency information and complements the lack of network data acquisition in emergency mapping. CARM uses a hierarchical model and the shortest path algorithm and allows the toponomy pieces to be joined as a full address. AEMEI analyzes the results of the emergency event and summarizes the advantages and disadvantages of the event framework. Experiments show that event frame technology can solve the problem of emergency information drawing and provides reference cases for other applications. When the emergency disaster is about to occur, the relevant departments query emergency's data that has occurred in the past. They can make arrangements ahead of schedule which defense and reducing disaster. The technology decreases the number of casualties and property damage in the country and world. This is of great significance to the state and society.

Novel approach for deriving genome wide SNP analysis data from archived blood spots

PubMed Central

2012-01-01

Background The ability to transport and store DNA at room temperature in low volumes has the advantage of optimising cost, time and storage space. Blood spots on adapted filter papers are popular for this, with FTA (Flinders Technology Associates) Whatman™TM technology being one of the most recent. Plant material, plasmids, viral particles, bacteria and animal blood have been stored and transported successfully using this technology, however the method of porcine DNA extraction from FTA Whatman™TM cards is a relatively new approach, allowing nucleic acids to be ready for downstream applications such as PCR, whole genome amplification, sequencing and subsequent application to single nucleotide polymorphism microarrays has hitherto been under-explored. Findings DNA was extracted from FTA Whatman™TM cards (following adaptations of the manufacturer’s instructions), whole genome amplified and subsequently analysed to validate the integrity of the DNA for downstream SNP analysis. DNA was successfully extracted from 288/288 samples and amplified by WGA. Allele dropout post WGA, was observed in less than 2% of samples and there was no clear evidence of amplification bias nor contamination. Acceptable call rates on porcine SNP chips were also achieved using DNA extracted and amplified in this way. Conclusions DNA extracted from FTA Whatman cards is of a high enough quality and quantity following whole genomic amplification to perform meaningful SNP chip studies. PMID:22974252

Assessment of desalination technologies for treatment of a highly saline brine from a potential CO 2 storage site

DOE PAGES

Kaplan, Ruth; Mamrosh, Darryl; Salih, Hafiz H.; ...

2016-11-12

Brine extraction is a promising strategy for the management of increased reservoir pressure, resulting from carbon dioxide (CO 2) injection in deep saline reservoirs. The extracted brines usually have high concentrations of total dissolved solids (TDS) and various contaminants, and require proper disposal or treatment. In this article, first by conducting a critical review, we evaluate the applicability, limits, and advantages or challenges of various commercially available and emerging desalination technologies that can potentially be employed to treat the highly saline brine (with TDS values >70.000 ppm) and those that are applicable to a ~200,000 ppm TDS brine extracted frommore » the Mt. Simon Sandstone, a potential CO 2 storage site in Illinois, USA. Based on the side-by-side comparison of technologies, evaporators are selected as the most suitable existing technology for treating Mt. Simon brine. Process simulations are then conducted for a conceptual design for desalination of 454 m 3/h (2000 gpm) pretreated brine for near-zero liquid discharge by multi-effect evaporators. In conclusion, the thermal energy demand is estimated at 246kWh perm 3 of recoveredwater, ofwhich 212kWh/m 3 is required for multiple-effect evaporation and the remainder for salt drying. The process also requires additional electrical power of ~2 kWh/m 3.« less

Smart technologies to enhance social connectedness in older people who live at home.

PubMed

Morris, Meg E; Adair, Brooke; Ozanne, Elizabeth; Kurowski, William; Miller, Kimberly J; Pearce, Alan J; Santamaria, Nick; Long, Maureen; Ventura, Cameron; Said, Catherine M

2014-09-01

To examine the effectiveness of smart technologies in improving or maintaining the social connectedness of older people living at home. We conducted a systematic review and critical evaluation of research articles published between 2000 and 2013. Article screening, data extraction and quality assessment (using the Downs and Black checklist) were conducted by two independent researchers. Eighteen publications were identified that evaluated the effect of smart technologies on dimensions of social connectedness. Fourteen studies reported positive outcomes in aspects such as social support, isolation and loneliness. There was emerging evidence that some technologies augmented the beneficial effects of more traditional aged-care services. Smart technologies, such as tailored internet programs, may help older people better manage and understand various health conditions, resulting in subsequent improvements in aspects of social connectedness. Further research is required regarding how technological innovations could be promoted, marketed and implemented to benefit older people. © 2014 ACOTA.

Technological change in revitalization - Phytoremediation and the role of nonknowledge.

PubMed

Bleicher, Alena

2016-12-15

In the 1990s, remediation methods that use plants to investigate and extract contaminations were developed. According to their proponents, these technologies have considerable potential for greening remediation and to develop a more sustainable trajectory for revitalization. Although a great deal of research has been conducted on these technologies they have, so far, rarely been applied in European countries. This article will contribute a perspective from social science to this debate. By taking an approach inspired by social science practice theories, attention will be drawn to a specific socio-cultural aspect: dealing with nonknowledge. The analysis of remediation practices reveals how the phenomenon of nonknowledge becomes relevant in the process of inventing and applying new technologies. This allows for a better understanding of technological innovation processes in remediation. Based on this understanding strategies are suggested which might increase the use of plant-based technologies in remediation and site management. Copyright © 2016 Elsevier Ltd. All rights reserved.

Soil vapor extraction with dewatering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thomson, N.R.

1996-08-01

The physical treatment technology of soil vapor extraction (SVE) is reliable, safe, robust, and able to remove significant amounts of mass at a relatively low cost. SVE combined with a pump-and-treat system to create a dewatered zone has the opportunity to remove more mass with the added cost of treating the extracted groundwater. Various limiting processes result in a significant reduction in the overall mass removal rates from a SVE system in porous media. Only pilot scale, limited duration SVE tests conducted in low permeability media have been reported in the literature. It is expected that the presence of amore » fracture network in low permeability media will add another complexity to the limiting conditions surrounding the SVE technology. 20 refs., 4 figs.« less

Linear feature extraction from radar imagery: SBIR (Small Business Innovative Research) phase 2, option 1

NASA Astrophysics Data System (ADS)

Conner, Gary D.; Milgram, David L.; Lawton, Daryl T.; McConnell, Christopher C.

1988-04-01

The goal of this effort is to develop and demonstrate prototype processing capabilities for a knowledge-based system to automatically extract and analyze linear features from synthetic aperture radar (SAR) imagery. This effort constitutes Phase 2 funding through the Defense Small Business Innovative Research (SBIR) Program. Previous work examined the feasibility of the technology issues involved in the development of an automatedlinear feature extraction system. This Option 1 Final Report documents this examination and the technologies involved in automating this image understanding task. In particular, it reports on a major software delivery containing an image processing algorithmic base, a perceptual structures manipulation package, a preliminary hypothesis management framework and an enhanced user interface.

A comprehensive guide of remediation technologies for oil contaminated soil - Present works and future directions.

PubMed

Lim, Mee Wei; Lau, Ee Von; Poh, Phaik Eong

2016-08-15

Oil spills result in negative impacts on the environment, economy and society. Due to tidal and waves actions, the oil spillage affects the shorelines by adhering to the soil, making it difficult for immediate cleaning of the soil. As shoreline clean-up is the most costly component of a response operation, there is a need for effective oil remediation technologies. This paper provides a review on the remediation technologies for soil contaminated with various types of oil, including diesel, crude oil, petroleum, lubricating oil, bitumen and bunker oil. The methods discussed include solvent extraction, bioremediation, phytoremediation, chemical oxidation, electrokinetic remediation, thermal technologies, ultrasonication, flotation and integrated remediation technologies. Each of these technologies was discussed, and associated with their advantages, disadvantages, advancements and future work in detail. Nonetheless, it is important to note that no single remediation technology is considered the best solution for the remediation of oil contaminated soil. This review provides a comprehensive literature on the various remediation technologies studied in the removal of different oil types from soil. Copyright © 2016 Elsevier Ltd. All rights reserved.

The 3-D image recognition based on fuzzy neural network technology

NASA Technical Reports Server (NTRS)

Hirota, Kaoru; Yamauchi, Kenichi; Murakami, Jun; Tanaka, Kei

1993-01-01

Three dimensional stereoscopic image recognition system based on fuzzy-neural network technology was developed. The system consists of three parts; preprocessing part, feature extraction part, and matching part. Two CCD color camera image are fed to the preprocessing part, where several operations including RGB-HSV transformation are done. A multi-layer perception is used for the line detection in the feature extraction part. Then fuzzy matching technique is introduced in the matching part. The system is realized on SUN spark station and special image input hardware system. An experimental result on bottle images is also presented.

Recent patents on the extraction of carotenoids.

PubMed

Riggi, Ezio

2010-01-01

This article reviews the patents that have been presented during the last decade related to the extraction of carotenoids from various forms of organic matter (fruit, vegetables, animals), with an emphasis on the methods and mechanisms exploited by these technologies, and on technical solutions for the practical problems related to these technologies. I present and classify 29 methods related to the extraction processes (physical, mechanical, chemical, and enzymatic). The large number of processes for extraction by means of supercritical fluids and the growing number of large-scale industrial plants suggest a positive trend towards using this technique that is currently slowed by its cost. This trend should be reinforced by growing restrictions imposed on the use of most organic solvents for extraction of food products and by increasingly strict waste management regulations that are indirectly promoting the use of extraction processes that leave the residual (post-extraction) matrix substantially free from solvents and compounds that must subsequently be removed or treated. None of the reviewed approaches is the best answer for every extractable compound and source, so each should be considered as one of several alternatives, including the use of a combination of extraction approaches.

Implantable brain computer interface: challenges to neurotechnology translation.

PubMed

Konrad, Peter; Shanks, Todd

2010-06-01

This article reviews three concepts related to implantable brain computer interface (BCI) devices being designed for human use: neural signal extraction primarily for motor commands, signal insertion to restore sensation, and technological challenges that remain. A significant body of literature has occurred over the past four decades regarding motor cortex signal extraction for upper extremity movement or computer interface. However, little is discussed regarding postural or ambulation command signaling. Auditory prosthesis research continues to represent the majority of literature on BCI signal insertion. Significant hurdles continue in the technological translation of BCI implants. These include developing a stable neural interface, significantly increasing signal processing capabilities, and methods of data transfer throughout the human body. The past few years, however, have provided extraordinary human examples of BCI implant potential. Despite technological hurdles, proof-of-concept animal and human studies provide significant encouragement that BCI implants may well find their way into mainstream medical practice in the foreseeable future.

Classifying patents based on their semantic content.

PubMed

Bergeaud, Antonin; Potiron, Yoann; Raimbault, Juste

2017-01-01

In this paper, we extend some usual techniques of classification resulting from a large-scale data-mining and network approach. This new technology, which in particular is designed to be suitable to big data, is used to construct an open consolidated database from raw data on 4 million patents taken from the US patent office from 1976 onward. To build the pattern network, not only do we look at each patent title, but we also examine their full abstract and extract the relevant keywords accordingly. We refer to this classification as semantic approach in contrast with the more common technological approach which consists in taking the topology when considering US Patent office technological classes. Moreover, we document that both approaches have highly different topological measures and strong statistical evidence that they feature a different model. This suggests that our method is a useful tool to extract endogenous information.

Deterministic implementation of a bright, on-demand single photon source with near-unity indistinguishability via quantum dot imaging.

PubMed

He, Yu-Ming; Liu, Jin; Maier, Sebastian; Emmerling, Monika; Gerhardt, Stefan; Davanço, Marcelo; Srinivasan, Kartik; Schneider, Christian; Höfling, Sven

2017-07-20

Deterministic techniques enabling the implementation and engineering of bright and coherent solid-state quantum light sources are key for the reliable realization of a next generation of quantum devices. Such a technology, at best, should allow one to significantly scale up the number of implemented devices within a given processing time. In this work, we discuss a possible technology platform for such a scaling procedure, relying on the application of nanoscale quantum dot imaging to the pillar microcavity architecture, which promises to combine very high photon extraction efficiency and indistinguishability. We discuss the alignment technology in detail, and present the optical characterization of a selected device which features a strongly Purcell-enhanced emission output. This device, which yields an extraction efficiency of η = (49 ± 4) %, facilitates the emission of photons with (94 ± 2.7) % indistinguishability.

Classifying patents based on their semantic content

PubMed Central

2017-01-01

In this paper, we extend some usual techniques of classification resulting from a large-scale data-mining and network approach. This new technology, which in particular is designed to be suitable to big data, is used to construct an open consolidated database from raw data on 4 million patents taken from the US patent office from 1976 onward. To build the pattern network, not only do we look at each patent title, but we also examine their full abstract and extract the relevant keywords accordingly. We refer to this classification as semantic approach in contrast with the more common technological approach which consists in taking the topology when considering US Patent office technological classes. Moreover, we document that both approaches have highly different topological measures and strong statistical evidence that they feature a different model. This suggests that our method is a useful tool to extract endogenous information. PMID:28445550

A review of electrostatic monitoring technology: The state of the art and future research directions

NASA Astrophysics Data System (ADS)

Wen, Zhenhua; Hou, Junxing; Atkin, Jason

2017-10-01

Electrostatic monitoring technology is a useful tool for monitoring and detecting component faults and degradation, which is necessary for system health management. It encompasses three key research areas: sensor technology; signal detection, processing and feature extraction; and verification experimentation. It has received considerable recent attention for condition monitoring due to its ability to provide warning information and non-obstructive measurements on-line. A number of papers in recent years have covered specific aspects of the technology, including sensor design optimization, sensor characteristic analysis, signal de-noising and practical applications of the technology. This paper provides a review of the recent research and of the development of electrostatic monitoring technology, with a primary emphasis on its application for the aero-engine gas path. The paper also presents a summary of some of the current applications of electrostatic monitoring technology in other industries, before concluding with a brief discussion of the current research situation and possible future challenges and research gaps in this field. The aim of this paper is to promote further research into this promising technology by increasing awareness of both the potential benefits of the technology and the current research gaps.

Abuse-deterrent features of an extended-release morphine drug product developed using a novel injection-molding technology for oral drug delivery.

PubMed

Skak, Nikolaj; Elhauge, Torben; Dayno, Jeffrey M; Lindhardt, Karsten

A novel technology platform (Guardian™ Technology, Egalet Corporation, Wayne, PA) was used to manufacture morphine abuse-deterrent (AD), extended-release (ER), injection-molded tablets (morphine-ADER-IMT; ARYMO® ER [morphine sulfate] ER tablets; Egalet Corporation), a recently approved morphine product with AD labeling. The aim of this article is to highlight how the features of Guardian™ Technology are linked to the ER profile and AD characteristics of morphine-ADER-IMT. The ER profile of morphine-ADER-IMT is attributed to the precise release of morphine from the polymer matrix. The approved dosage strengths of morphine-ADER-IMT are bioequivalent to corresponding dosage strengths of morphine ER (MS Contin®; Purdue Pharma LP, Stamford, CT). Morphine-ADER-IMT was very resistant to physical manipulations intended to reduce particle size, with <10 percent of particles being reduced to <500µm, regarded by the US Food and Drug Administration as a relevant cutoff for potential insufflation in their generic solid oral AD opioid guidance. Furthermore, morphine was not readily extracted from the polymer matrix of morphine-ADER-IMT in small- or large-volume solvent extraction studies that evaluated the potential for intravenous and oral abuse. The ER profile and AD characteristics of morphine-ADER-IMT are a result of Guardian™ Technology. The combination of the polyethylene oxide matrix and the use of injection molding differentiate morphine-ADER-IMT from other approved AD opioids that deter abuse using physical and chemical barriers. The high degree of flexibility of the Guardian™ Technology enables the development of products that can be tailored to almost any desired release profile; as such, it is a technology platform that may be useful for the development of a wide range of pharmaceutical products.

Organizational issues in the implementation and adoption of health information technology innovations: an interpretative review.

PubMed

Cresswell, Kathrin; Sheikh, Aziz

2013-05-01

Implementations of health information technologies are notoriously difficult, which is due to a range of inter-related technical, social and organizational factors that need to be considered. In the light of an apparent lack of empirically based integrated accounts surrounding these issues, this interpretative review aims to provide an overview and extract potentially generalizable findings across settings. We conducted a systematic search and critique of the empirical literature published between 1997 and 2010. In doing so, we searched a range of medical databases to identify review papers that related to the implementation and adoption of eHealth applications in organizational settings. We qualitatively synthesized this literature extracting data relating to technologies, contexts, stakeholders, and their inter-relationships. From a total body of 121 systematic reviews, we identified 13 systematic reviews encompassing organizational issues surrounding health information technology implementations. By and large, the evidence indicates that there are a range of technical, social and organizational considerations that need to be deliberated when attempting to ensure that technological innovations are useful for both individuals and organizational processes. However, these dimensions are inter-related, requiring a careful balancing act of strategic implementation decisions in order to ensure that unintended consequences resulting from technology introduction do not pose a threat to patients. Organizational issues surrounding technology implementations in healthcare settings are crucially important, but have as yet not received adequate research attention. This may in part be due to the subjective nature of factors, but also due to a lack of coordinated efforts toward more theoretically-informed work. Our findings may be used as the basis for the development of best practice guidelines in this area. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

PERFORMANCE OF ACTIVE IN SITU REMEDIAL TECHNOLOGY FOR TREATMENT OF MTBE AND BENZENE AT UST SOURCE AREAS IN KANSAS

EPA Science Inventory

Both MtBE and Benzene are present at over 86% of the Underground Storage Tank sites in Kansas, USA that require active remediation. In situ remedial technologies, consisting primarily of soil vapor extraction and air sparging, are the preferred choice for treatment for MtBE site...

Connectivism in Learning Activity Design: Implications for Pedagogically-Based Technology Adoption in African Higher Education Contexts

ERIC Educational Resources Information Center

Kizito, Rita Ndagire

2016-01-01

This paper examines the possible characteristics and the value of designing learning activities grounded in connectivism--an emerging learning theory. It is an exploratory attempt to connect the theory to the prevailing technology adoption archetypes used in African contexts with the aim of extracting influences that could shape pedagogical…

Next generation sequencing technology: a powerful tool for the genome characterization of sugarcane mosaic virus from Sorghum almum

USDA-ARS?s Scientific Manuscript database

Next generation sequencing (NGS) technology was used to analyze the occurrence of viruses in Sorghum almum plants in Florida exhibiting mosaic symptoms. Total RNA was extracted from symptomatic leaves and used as a template for cDNA library preparation. The resulting library was sequenced on an Illu...

A Meta-Analysis of the Effects of Computer Technology on School Students' Mathematics Learning

ERIC Educational Resources Information Center

Li, Qing; Ma, Xin

2010-01-01

This study examines the impact of computer technology (CT) on mathematics education in K-12 classrooms through a systematic review of existing literature. A meta-analysis of 85 independent effect sizes extracted from 46 primary studies involving a total of 36,793 learners indicated statistically significant positive effects of CT on mathematics…

Aquantis Ocean Current Turbine Development Project Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fleming, Alex J.

2014-08-23

The Aquantis® Current Plane (“C-Plane”) technology developed by Dehlsen Associates, LLC (DA) and Aquantis, Inc. is an ocean current turbine designed to extract kinetic energy from ocean currents. The technology is capable of achieving competitively priced base-load, continuous, and reliable power generation from a source of renewable energy not before possible in this scale or form.

Technology-Enhanced Learning and Co-Operative Practice against the Neoliberal University

ERIC Educational Resources Information Center

Hall, Richard

2016-01-01

Neoliberalism is a global pedagogical project aimed at the dispossession of free time so that all of life becomes productive, and education is a central institutional means for its realisation. This project aims at marketising all of social life, so that life becomes predicated upon the extraction of value. In part the deployment of technologies,…

Reusable Software Technology

NASA Technical Reports Server (NTRS)

Morgan, Timothy E.

1995-01-01

The objective of the Reusable Software System (RSS) is to provide NASA Langley Research Center and its contractor personnel with a reusable software technology through the Internet. The RSS is easily accessible, provides information that is extractable, and the capability to submit information or data for the purpose of scientific research at NASA Langley Research Center within the Atmospheric Science Division.

Current knowledge and potential applications of cavitation technologies for the petroleum industry.

PubMed

Avvaru, Balasubrahmanyam; Venkateswaran, Natarajan; Uppara, Parasuveera; Iyengar, Suresh B; Katti, Sanjeev S

2018-04-01

Technologies based on cavitation, produced by either ultrasound or hydrodynamic means, are part of growing literature for individual refinery unit processes. In this review, we have explained the mechanism through which these cavitation technologies intensify individual unit processes such as enhanced oil recovery, demulsification of water in oil emulsions during desalting stage, crude oil viscosity reduction, oxidative desulphurisation/demetallization, and crude oil upgrading. Apart from these refinery processes, applications of this technology are also mentioned for other potential crude oil sources such as oil shale and oil sand extraction. The relative advantages and current situation of each application/process at commercial scale is explained. Copyright © 2017 Elsevier B.V. All rights reserved.

Recent Developments in Australian Gold Extraction.

ERIC Educational Resources Information Center

Thiele, Rodney B.

1995-01-01

Describes new technologies that have greatly improved the extraction efficiency of gold ore, including: altering plant layout to promote efficiency, engaging Filiblast forced oxidation and bioxidation systems, and updating the electrowinning procedure at the gold recovery stage. (JRH)

Isolation of Mitochondrial DNA from Single, Short Hairs without Roots Using Pressure Cycling Technology.

PubMed

Harper, Kathryn A; Meiklejohn, Kelly A; Merritt, Richard T; Walker, Jessica; Fisher, Constance L; Robertson, James M

2018-02-01

Hairs are commonly submitted as evidence to forensic laboratories, but standard nuclear DNA analysis is not always possible. Mitochondria (mt) provide another source of genetic material; however, manual isolation is laborious. In a proof-of-concept study, we assessed pressure cycling technology (PCT; an automated approach that subjects samples to varying cycles of high and low pressure) for extracting mtDNA from single, short hairs without roots. Using three microscopically similar donors, we determined the ideal PCT conditions and compared those yields to those obtained using the traditional manual micro-tissue grinder method. Higher yields were recovered from grinder extracts, but yields from PCT extracts exceeded the requirements for forensic analysis, with the DNA quality confirmed through sequencing. Automated extraction of mtDNA from hairs without roots using PCT could be useful for forensic laboratories processing numerous samples.

[Study on extraction and purification technology of Hubei ophiopogon saponins].

PubMed

Lin, Yun-Han; Li, Chong-Ming; Li, Xiao-Dong; Xiang, Yang; Zhang, Ya-Qin; Zhang, Xiao-Cun; Liu, Xia

2013-05-01

To explore the extraction and purification technology of total saponins from the effective parts of Liriope spicata. Orthogonal design was used. Macroporous resin was selected to separate and purify total saponin from the effective parts of Liriope spicata. The process validation was conducted. The total saponins was determined by Ultraviolet Spectrophotometry. The optimal extraction conditions were as follows: 10 times the amount of ethanol (70%) for each occasion and hot reflux (3 x 2 h). Total saponins was purified by D101 macroporous resin. The concentration of eluting ethanol was 50% - 70%. Ethanol (70%) was selected as the best eluent. The result of process validation was consistent with the study. The process is simple and stable enough to significantly improve the extraction rate of the effective parts. The study can provide reference for the research and production of effective parts of traditional Chinese medicine such as Liriope spicata.

[Optimization of processing technology for semen cuscuta by uniform and regression analysis].

PubMed

Li, Chun-yu; Luo, Hui-yu; Wang, Shu; Zhai, Ya-nan; Tian, Shu-hui; Zhang, Dan-shen

2011-02-01

To optimize the best preparation technology for the contains of total flavornoids, polysaccharides, the percentage of water and alcohol-soluble components in Semen Cuscuta herb processing. UV-spectrophotometry was applied to determine the contains of total flavornoids and polysaccharides, which were extracted from Semen Cuscuta. And the processing was optimized by the way of uniform design and contour map. The best preparation technology was satisfied with some conditions as follows: baking temperature 150 degrees C, baking time 140 seconds. The regression models are notable and reasonable, which can forecast results precisely.

Control technology appendices for pollution control technical manuals. Final report, June 1982-February 1983

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1983-04-01

The document is one of six technical handbooks prepared by EPA to help government officials granting permits to build synfuels facilities, synfuels process developers, and other interested parties. They provide technical data on waste streams from synfuels facilities and technologies capable of controlling them. Process technologies covered in the manuals include coal gasification, coal liquefaction by direct and idirect processing, and the extraction of oil from shale. The manuals offer no regulatory guidance, allowing the industry flexibility in deciding how best to comply with environmental regulations.

Continuation of Crosscutting Technology Development at Cast

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yoon, Roe-Hoan

2012-03-31

This Final Technical Report describes progress made on the sub-projects awarded in the Cooperative Agreement DE-FC26-05NT42457: Continuation of Crosscutting Technology Development at Center for Advanced Separation Technologies (CAST). The final reports for each sub-project are attached in the appendix. Much of the research to be conducted with Cooperative Agreement funds will be longer-term, high-risk, basic research and will be carried out in five broad areas: a) Solid-solid separation b) Solid-liquid separation c) Chemical/Biological Extraction d) Modeling and Control, and e) Environmental Control.

Rural hospital information technology implementation for safety and quality improvement: lessons learned.

PubMed

Tietze, Mari F; Williams, Josie; Galimbertti, Marisa

2009-01-01

This grant involved a hospital collaborative for excellence using information technology over 3-year period. The project activities focused on the improvement of patient care safety and quality in Southern rural and small community hospitals through the use of technology and education. The technology component of the design involved the implementation of a Web-based business analytic tool that allows hospitals to view data, create reports, and analyze their safety and quality data. Through a preimplementation and postimplementation comparative design, the focus of the implementation team was twofold: to recruit participant hospitals and to implement the technology at each of the 66 hospital sites. Rural hospitals were defined as acute care hospitals located in a county with a population of less than 100 000 or a state-administered Critical Access Hospital, making the total study population target 188 hospitals. Lessons learned during the information technology implementation of these hospitals are reflective of the unique culture, financial characteristics, organizational structure, and technology architecture of rural hospitals. Specific steps such as recruitment, information technology assessment, conference calls for project planning, data file extraction and transfer, technology training, use of e-mail, use of telephones, personnel management, and engaging information technology vendors were found to vary greatly among hospitals.

Analysis of fractionation in corn-to-ethanol plants

NASA Astrophysics Data System (ADS)

Nelson, Camille

As the dry grind ethanol industry has grown, the research and technology surrounding ethanol production and co-product value has increased. Including use of back-end oil extraction and front-end fractionation. Front-end fractionation is pre-fermentation separation of the corn kernel into 3 fractions: endosperm, bran, and germ. The endosperm fraction enters the existing ethanol plant, and a high protein DDGS product remains after fermentation. High value oil is extracted out of the germ fraction. This leaves corn germ meal and bran as co-products from the other two streams. These 3 co-products have a very different composition than traditional corn DDGS. Installing this technology allows ethanol plants to increase profitability by tapping into more diverse markets, and ultimately could allow for an increase in profitability. An ethanol plant model was developed to evaluate both back-end oil extraction and front-end fractionation technology and predict the change in co-products based on technology installed. The model runs in Microsoft Excel and requires inputs of whole corn composition (proximate analysis), amino acid content, and weight to predict the co-product quantity and quality. User inputs include saccharification and fermentation efficiencies, plant capacity, and plant process specifications including front-end fractionation and backend oil extraction, if applicable. This model provides plants a way to assess and monitor variability in co-product composition due to the variation in whole corn composition. Additionally the co-products predicted in this model are entered into the US Pork Center of Excellence, National Swine Nutrition Guide feed formulation software. This allows the plant user and animal nutritionists to evaluate the value of new co-products in existing animal diets.

Industrial applications of hot dry rock geothermal energy

NASA Astrophysics Data System (ADS)

Duchane, D. V.

1992-07-01

Geothermal resources in the form of naturally occurring hot water or steam have been utilized for many years. While these hydrothermal resources are found in many places, the general case is that the rock at depth is hot, but does not contain significant amounts of mobile fluid. An extremely large amount of geothermal energy is found around the world in this hot dry rock (HDR). Technology has been under development for more than twenty years at the Los Alamos National Laboratory in the United States and elsewhere to develop the technology to extract the geothermal energy from HDR in a form useful for electricity generation, space heating, or industrial processing. HDR technology is especially attractive for industrial applications because of the ubiquitous distribution of the HDR resource and the unique aspects of the process developed to recover it. In the HDR process, as developed at Los Alamos, water is pumped down a well under high pressure to open up natural joints in hot rock and create an artificial geothermal reservoir. Energy is extracted by circulating water through the reservoir. Pressurized hot water is returned to the surface through the production well, and its thermal energy is extracted for practical use. The same water is then recirculated through the system to mine more geothermal heat. Construction of a pilot HDR facility at Fenton Hill, NM, USA, has recently been completed by the Los Alamos National Laboratory. It consists of a large underground reservoir, a surface plant, and the connecting wellbores. This paper describes HDR technology and the current status of the development program. Novel industrial applications of geothermal energy based on the unique characteristics of the HDR energy extraction process are discussed.

A Review on Phytosome Technology as a Novel Approach to Improve The Bioavailability of Nutraceuticals

NASA Astrophysics Data System (ADS)

Amin, Tawheed; Bhat, Suman Vikas

2012-08-01

The bioavailability and absorption of water soluble phytoconstituents is erratic due to poor solubility of these constituents in gastrointestinal tract. This can be overcome by a novel delivery system known as phytosome technology in which water soluble phytoconstituents are allowed to react with phospholipids. For better and improved bioavailability, natural phytoconstituents must have a good balance between hydrophilicity (helps in dissolution in gastro-intestinal fluids) and hydrophobicity (helps to cross lipid rich cell membranes). This is achieved through phytosome technology. Phospholipids have a dual solubility and acts as an emulsifier. Phytosome technology acts as a bridge between novel and conventional delivery systems. Many products are available in the market based on this phytosome technology which include popular herbal extracts such as Ginkgo biloba, Silybum marianum, grape seed, olive oil flavonoids etc.

Mars in Situ Resource Utilization Technology Evaluation

NASA Technical Reports Server (NTRS)

Muscatello, Anthony C.; Santago-Maldonado, Edgardo

2012-01-01

We have examined the technologies required to enable Mars In-Situ Resource Utilization (ISRU) because our understanding of Mars resources has changed significantly in the last five years as a result of recent robotic missions to the red planet. Two major developments, (1) confirmation of the presence of near-surface water in the form of ice in very large amounts at high latitudes by the Phoenix Lander and (2) the likely existence of water at lower latitudes in the form of hydrates or ice in the top one meter of the regolith, have the potential to change ISRU technology selection. A brief technology assessment was performed for the most promising Mars atmospheric gas processing techniques: Reverse Water Gas Shift (RWGS) and Methanation (aka Sabatier), as well as an overview of soil processing technology to extract water from Martian soil.

Mars In-Situ Resource Utilization Technology Evaluation

NASA Technical Reports Server (NTRS)

Santiago-Maldonado, Edgardo; Muscatello, Anthony

2011-01-01

We have examined the technologies required to enable Mars Tn-Situ Resource Utilization (ISRU) because our understanding of Mars resources has changed significantly in the last five years as a result of recent robotic missions to the red planet [1-4]. Two major developments, (1) confirmation of the presence of near-surface water in the form of ice in very large amounts at high latitudes by the Phoenix Lander and (2) the likely existence of water at lower latitudes in the form of hydrates or ice in the top one meter of the regolith, have the potential to change ISRU technology selection. A brief technology assessment was performed for the most promising Mars atmospheric gas processing techniques: Reverse Water Gas Shift (RWGS) and Methanation (aka Sabatier), as well as an overview of soil.processing technology to extract water from Martian soil.

Acid-switched Eu(III) coordination inside reverse aggregates: Insights into a synergistic liquid-liquid extraction system

DOE PAGES

Ellis, Ross J.

2016-08-09

Determining the structure of complex solutions bearing metal ions is challenging, but crucial for developing important technologies such as liquid-liquid extraction for metal refining and separation purposes. Herein, the structure of an organic Eu(III) solution consisting a binary mixture of lipophilic ligands di-2-ethylhexyl phosphoric acid (HDEHP) and tetraoctyl diglycolamide (TODGA) in dodecane is studied using synchrotron small angle X-ray scattering (SAXS) and X-ray absorption fine structure spectroscopy (EXAFS). This system is of technological importance in f-element separation for nuclear fuel cycle applications, where extraction is controlled by varying nitric acid concentration. Extraction is promoted at low and high concentration, butmore » is retarded at intermediate concentration, leading to a U-shaped function; the structural origins of which we investigate. At the nanoscale, the solution is apparently comprised of reverse micelles with polar cores of approximately 1 nm in size, and these remain virtually unchanged as acid concentration is varied. Inside the polar cores, the coordination environment of Eu(III) switches from a 9-coordinate [Eu(TODGA) 3] 3+ motif at high acid, to a 6-coordinate HDEHP-dominated complex resembling Eu(HDEHP·DEHP) 3 at low acid. The results show that extraction is controlled within the coordination sphere, where it is promoted under conditions that favor coordination of either one of the two organic ligands, but is retarded under conditions that encourage mixed complexes. Lastly, our results link solution structure with ion transport properties in a technologically-important liquid-liquid ion extraction system.« less

Application of ionic liquid for extraction and separation of bioactive compounds from plants.

PubMed

Tang, Baokun; Bi, Wentao; Tian, Minglei; Row, Kyung Ho

2012-09-01

In recent years, ionic liquids (ILs), as green and designer solvents, have accelerated research in analytical chemistry. This review highlights some of the unique properties of ILs and provides an overview of the preparation and application of IL or IL-based materials to extract bioactive compounds in plants. IL or IL-based materials in conjunction with liquid-liquid extraction (LLE), ultrasonic-assisted extraction (UAE), microwave-assisted extraction (MAE), high performance liquid chromatography (HPLC) and solid-phase extraction (SPE) analytical technologies etc., have been applied successfully to the extraction or separation of bioactive compounds from plants. This paper reviews the available data and references to examine the advantages of IL and IL-based materials in these applications. In addition, the main target compounds reviewed in this paper are bioactive compounds with multiple therapeutic effects and pharmacological activities. Based on the importance of the targets, this paper reviews the applications of ILs, IL-based materials or co-working with analytical technologies. The exploitation of new applications of ILs on the extraction of bioactive compounds from plant samples is expected to increase. Copyright © 2012 Elsevier B.V. All rights reserved.

Three-Dimensional Reconstruction of the Virtual Plant Branching Structure Based on Terrestrial LIDAR Technologies and L-System

NASA Astrophysics Data System (ADS)

Gong, Y.; Yang, Y.; Yang, X.

2018-04-01

For the purpose of extracting productions of some specific branching plants effectively and realizing its 3D reconstruction, Terrestrial LiDAR data was used as extraction source of production, and a 3D reconstruction method based on Terrestrial LiDAR technologies combined with the L-system was proposed in this article. The topology structure of the plant architectures was extracted using the point cloud data of the target plant with space level segmentation mechanism. Subsequently, L-system productions were obtained and the structural parameters and production rules of branches, which fit the given plant, was generated. A three-dimensional simulation model of target plant was established combined with computer visualization algorithm finally. The results suggest that the method can effectively extract a given branching plant topology and describes its production, realizing the extraction of topology structure by the computer algorithm for given branching plant and also simplifying the extraction of branching plant productions which would be complex and time-consuming by L-system. It improves the degree of automation in the L-system extraction of productions of specific branching plants, providing a new way for the extraction of branching plant production rules.

Development of a Kelp-type Structure Module in a Coastal Ocean Model to Assess the Hydrodynamic Impact of Seawater Uranium Extraction Technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Taiping; Khangaonkar, Tarang; Long, Wen

2014-02-07

In recent years, with the rapid growth of global energy demand, the interest in extracting uranium from seawater for nuclear energy has been renewed. While extracting seawater uranium is not yet commercially viable, it serves as a “backstop” to the conventional uranium resources and provides an essentially unlimited supply of uranium resource. With recent advances in seawater uranium extraction technology, extracting uranium from seawater could be economically feasible when the extraction devices are deployed at a large scale (e.g., several hundred km2). There is concern however that the large scale deployment of adsorbent farms could result in potential impacts tomore » the hydrodynamic flow field in an oceanic setting. In this study, a kelp-type structure module was incorporated into a coastal ocean model to simulate the blockage effect of uranium extraction devices on the flow field. The module was quantitatively validated against laboratory flume experiments for both velocity and turbulence profiles. The model-data comparison showed an overall good agreement and validated the approach of applying the model to assess the potential hydrodynamic impact of uranium extraction devices or other underwater structures in coastal oceans.« less

Extracting ballistic forensic intelligence: microstamped firearms deliver data for illegal firearm traffic mapping: technology, implementation, and applications

NASA Astrophysics Data System (ADS)

Ohar, Orest P.; Lizotte, Todd E.

2009-08-01

Over the years law enforcement has become increasingly complex, driving a need for a better level of organization of knowledge within policing. The use of COMPSTAT or other Geospatial Information Systems (GIS) for crime mapping and analysis has provided opportunities for careful analysis of crime trends. By identifying hotspots within communities, data collected and entered into these systems can be analyzed to determine how, when and where law enforcement assets can be deployed efficiently. This paper will introduce in detail, a powerful new law enforcement and forensic investigative technology called Intentional Firearm Microstamping (IFM). Once embedded and deployed into firearms, IFM will provide data for identifying and tracking the sources of illegally trafficked firearms within the borders of the United States and across the border with Mexico. Intentional Firearm Microstamping is a micro code technology that leverages a laser based micromachining process to form optimally located, microscopic "intentional structures and marks" on components within a firearm. Thus when the firearm is fired, these IFM structures transfer an identifying tracking code onto the expended cartridge that is ejected from the firearm. Intentional Firearm Microstamped structures are laser micromachined alpha numeric and encoded geometric tracking numbers, linked to the serial number of the firearm. IFM codes can be extracted quickly and used without the need to recover the firearm. Furthermore, through the process of extraction, IFM codes can be quantitatively verified to a higher level of certainty as compared to traditional forensic matching techniques. IFM provides critical intelligence capable of identifying straw purchasers, trafficking routes and networks across state borders and can be used on firearms illegally exported across international borders. This paper will outline IFM applications for supporting intelligence led policing initiatives, IFM implementation strategies, describe the how IFM overcomes the firearms stochastic properties and explain the code extraction technologies that can be used by forensic investigators and discuss the applications where the extracted data will benefit geospatial information systems for forensic intelligence benefit.

Extraction and utilization of the repeating patterns for CP writing in mask making

NASA Astrophysics Data System (ADS)

Shoji, Masahiro; Inoue, Tadao; Yamabe, Masaki

2010-05-01

In May 2006, the Mask Design, Drawing, and Inspection Technology Research Department (Mask D2I) at the Association of Super-Advanced Electronics Technologies (ASET) launched a 4-year program for reducing mask manufacturing cost and TAT by concurrent optimization of Mask Data Preparation (MDP), mask writing, and mask inspection [1]. Figure 1 shows an outline of the project at Mask D2I at ASET. As one of the tasks being pursued at the Mask Design Data Technology Research Laboratory we have evaluated the effect of reducing the writing shot counts by utilizing the repeating patterns, and that showed positive impact on mask making by using CP writing. During the past four years, we have developed a software to extract repeating patterns from fractured OPCed mask data and have evaluated the efficiency of reducing the writing shot counts using the repeating patterns with this software. In this evaluation, we have used many actual device production data obtained from the member companies of Mask D2I. To the extraction software, we added new functions for extracting common repeating patterns from a set of multiple masks, and studied how this step affects the ratio of reducing the shot counts in comparison to the case of utilization of the repeating patterns for single mask. We have also developed a software that uses the result of extracting repeating patterns and prepares writing-data for the MCC/CP writing system which has been developed at the Mask Writing Equipment Technology Research Laboratory. With this software, we have examined how EB proximity effect on CP writing affects in reducing the shot count where CP shots with large CD errors have to be divided into VSB shots. In this paper we will report on making common CP mask from a set of multiple actual device data by using these software, and will also report on the results of CP writing and calculation of writing-TAT by MCC/CP writing system.

Statistical Methods for Proteomic Biomarker Discovery based on Feature Extraction or Functional Modeling Approaches.

PubMed

Morris, Jeffrey S

2012-01-01

In recent years, developments in molecular biotechnology have led to the increased promise of detecting and validating biomarkers, or molecular markers that relate to various biological or medical outcomes. Proteomics, the direct study of proteins in biological samples, plays an important role in the biomarker discovery process. These technologies produce complex, high dimensional functional and image data that present many analytical challenges that must be addressed properly for effective comparative proteomics studies that can yield potential biomarkers. Specific challenges include experimental design, preprocessing, feature extraction, and statistical analysis accounting for the inherent multiple testing issues. This paper reviews various computational aspects of comparative proteomic studies, and summarizes contributions I along with numerous collaborators have made. First, there is an overview of comparative proteomics technologies, followed by a discussion of important experimental design and preprocessing issues that must be considered before statistical analysis can be done. Next, the two key approaches to analyzing proteomics data, feature extraction and functional modeling, are described. Feature extraction involves detection and quantification of discrete features like peaks or spots that theoretically correspond to different proteins in the sample. After an overview of the feature extraction approach, specific methods for mass spectrometry ( Cromwell ) and 2D gel electrophoresis ( Pinnacle ) are described. The functional modeling approach involves modeling the proteomic data in their entirety as functions or images. A general discussion of the approach is followed by the presentation of a specific method that can be applied, wavelet-based functional mixed models, and its extensions. All methods are illustrated by application to two example proteomic data sets, one from mass spectrometry and one from 2D gel electrophoresis. While the specific methods presented are applied to two specific proteomic technologies, MALDI-TOF and 2D gel electrophoresis, these methods and the other principles discussed in the paper apply much more broadly to other expression proteomics technologies.

[The method and application to construct experience recommendation platform of acupuncture ancient books based on data mining technology].

PubMed

Chen, Chuyun; Hong, Jiaming; Zhou, Weilin; Lin, Guohua; Wang, Zhengfei; Zhang, Qufei; Lu, Cuina; Lu, Lihong

2017-07-12

To construct a knowledge platform of acupuncture ancient books based on data mining technology, and to provide retrieval service for users. The Oracle 10 g database was applied and JAVA was selected as development language; based on the standard library and ancient books database established by manual entry, a variety of data mining technologies, including word segmentation, speech tagging, dependency analysis, rule extraction, similarity calculation, ambiguity analysis, supervised classification technology were applied to achieve text automatic extraction of ancient books; in the last, through association mining and decision analysis, the comprehensive and intelligent analysis of disease and symptom, meridians, acupoints, rules of acupuncture and moxibustion in acupuncture ancient books were realized, and retrieval service was provided for users through structure of browser/server (B/S). The platform realized full-text retrieval, word frequency analysis and association analysis; when diseases or acupoints were searched, the frequencies of meridian, acupoints (diseases) and techniques were presented from high to low, meanwhile the support degree and confidence coefficient between disease and acupoints (special acupoint), acupoints and acupoints in prescription, disease or acupoints and technique were presented. The experience platform of acupuncture ancient books based on data mining technology could be used as a reference for selection of disease, meridian and acupoint in clinical treatment and education of acupuncture and moxibustion.

TECHNOLOGY EVALUATION REPORT: SITE PROGRAM DEMONSTRATION TEST - ACCUTECH PNEUMATIC FRACTURING EXTRACTION AND HOT GAS INJECTION, PHASE 1 - VOLUME I

EPA Science Inventory

The Pneumatic Fracturing Extraction (PFE) process developed by Accutech Remedial Systems, Inc. makes it possible to use vapor extraction to remove volatile organics at increased rates from a broader range of vadose zones. The low permeability of silts, clays, shales, etc. would o...

Maintaining perspective on third molar extraction.

PubMed

Boughner, Julia C

2013-01-01

Third molar extraction is one of the most common oral surgeries performed on Canadian patients, particularly young adults. Vigorous debate persists about the risks of retention of asymptomatic impacted third molars, compared to extraction. The controversy centres on whether medical necessity justifies the cost of third molar extraction for the patient in terms of substantial pain and potential loss of income during recovery and for the federal or provincial health care systems, which may be billed for a portion of the surgical fees. Several research studies initiated by the American Association of Oral and Maxillofacial Surgeons (AAOMS) report new associations between oral disease and asymptomatic impacted third molars. These findings merit careful attention because they are being used by the AAOMS to advocate for prophylactic third molar extraction--an approach that contradicts the conclusions of a Canadian health technology report, American Public Health Association policy, and health technology reports from Sweden, Belgium and the UK. The decision to extract third molars seems most effective when made on a case-by-case basis that is tailored to each patient's health status and access to professional oral health care.

Study on Suitable Light Conditions and Efficient Lipid Extraction Technologies for Biodiesel Production Based on Microalgae

NASA Astrophysics Data System (ADS)

Wang, Yao; Zhang, Qingtao; Sun, Yuan; Yang, Chengjia

2018-01-01

As a new generation biodiesel feedstock, microalgae have most potential to replace fossil fuel. However, the limited scale and high cost are two bottleneck problems. Efficient microwave-assisted lipid extraction technologies and suitable light conditions for Chlorella Sorokiniana need further study for lowering the cost. In this study, three photoperiod groups(24L:0D, 12L:12D, 0L:24D), three illumination intensity groups (1800 lux, 3600 lux, 5400 lux)and four light spectrum groups (Red, green, blue, and white) were used to culture Chlorella Sorokiniana to investigate those effects on algae growth rate and biomass accumulation. The suitable microwave treatment was also studied to achieve an optimizing quantum fracturing technology. 400 w, 750 w and 1000 w microwave power were set and 60 °C, 75 °C, 90 °C microwave conditions were investigated. The results showed that Chlorella Sorokiniana under 24L:0D photoperiod with 5400 lux white light can achieve better growth rate. The 90 °C / 1000w microwave treatment was identified as the most simple, easy, and effective way for lipid extraction from Chlorella Sorokiniana. As the raw material of biodiesel production, C18:1, C18:2 and C18:3 have accounted for important components of fatty acid in Chlorella Sorokiniana. Therefore, Chlorella Sorokiniana is a good raw material for the production of good quality biodiesel under suitable and efficient technologies.

Surrogate outcomes in health technology assessment: an international comparison.

PubMed

Velasco Garrido, Marcial; Mangiapane, Sandra

2009-07-01

Our aim was to review the recommendations given by health technology assessment (HTA) institutions in their methodological guidelines concerning the use of surrogate outcomes in their assessments. In a second step, we aimed at quantifying the role surrogate parameters take in assessment reports. We analyzed methodological papers and guidelines from HTA agencies with International Network of Agencies for Health Technology Assessment membership as well as from institutions related to pharmaceutical regulation (i.e., reimbursement, pricing). We analyzed the use of surrogate outcomes in a sample of HTA reports randomly drawn from the HTA database. We checked methods, results (including evidence tables), and conclusions sections and extracted the outcomes reported. We report descriptive statistics on the presence of surrogate outcomes in the reports. We identified thirty-four methodological guidelines, twenty of them addressing the issue of outcome parameter choice and the problematic of surrogate outcomes. Overall HTA agencies call on caution regarding the reliance on surrogate outcomes. None of the agencies has provided a list or catalog of acceptable and validated surrogate outcomes. We extracted the outcome parameter of 140 HTA reports. Only around half of the reports determined the outcomes for the assessment prospectively. Surrogate outcomes had been used in 62 percent of the reports. However, only 3.6 percent were based upon surrogate outcomes exclusively. All of them assessed diagnostic or screening technologies and the surrogate outcomes were predominantly test characteristics. HTA institutions seem to agree on a cautious approach to the use of surrogate outcomes in technology assessment. Thorough assessment of health technologies should not rely exclusively on surrogate outcomes.

How Are They Now? Longer Term Effects of eCoaching through Online Bug-in-Ear Technology

ERIC Educational Resources Information Center

Rock, Marcia L.; Schumacker, Randall E.; Gregg, Madeleine; Howard, Pamela W.; Gable, Robert A.; Zigmond, Naomi

2014-01-01

In this study, using mixed methods, we investigated the longer term effects of eCoaching through advanced online bug-in-ear (BIE) technology. Quantitative data on five dependent variables were extracted from 14 participants' electronically archived video files at three points in time--Spring 1 (i.e., baseline, which was the first semester of…

A Behavioural Approach to Understanding Semi-Subsistence Farmers' Technology Adoption Decisions: The Case of Improved Paddy-Prawn System in Indonesia

ERIC Educational Resources Information Center

Sambodo, Leonardo A. A. T.; Nuthall, Peter L.

2010-01-01

Purpose: This study traced the origins of subsistence Farmers' technology adoption attitudes and extracted the critical elements in their decision making systems. Design/Methodology/Approach: The analysis was structured using a model based on the Theory of Planned Behaviour (TPB). The role of a "bargaining process" was particularly…

Ultrasonic Clothes Drying Technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Patel, Viral; Momen, Ayyoub

Oak Ridge National Laboratory researchers Ayyoub Momen and Viral Patel demonstrate a direct contact ultrasonic clothes dryer under development by ORNL in collaboration with General Electric (GE) Appliances. This novel approach uses high-frequency mechanical vibrations instead of heat to extract moisture as cold mist, dramatically reducing drying time and energy use. Funding for this project was competitively awarded by DOE’s Building Technologies Office in 2014.

JPRS Report, Science & Technology, Europe

DTIC Science & Technology

1992-02-06

also sunflower and corn oil); bioethanol is produced by fermenting sugars extracted from sugar beets and grains. Regulations limit its share of...Metal Complexes"] [Text] Frankfurt, 16 Oct—The fermentation technology research team of the University of Bielefeld’s School of Engineering is...Frequency of Continuous Operation in Fermentation and Product Recovery" first two para- graphs are VDI NACHRICHTEN introduction] [Text

Enzyme assisted extraction of biomolecules as an approach to novel extraction technology: A review.

PubMed

Nadar, Shamraja S; Rao, Priyanka; Rathod, Virendra K

2018-06-01

An interest in the development of extraction techniques of biomolecules from various natural sources has increased in recent years due to their potential applications particularly for food and nutraceutical purposes. The presence of polysaccharides such as hemicelluloses, starch, pectin inside the cell wall, reduces the extraction efficiency of conventional extraction techniques. Conventional techniques also suffer from low extraction yields, time inefficiency and inferior extract quality due to traces of organic solvents present in them. Hence, there is a need of the green and novel extraction methods to recover biomolecules. The present review provides a holistic insight to various aspects related to enzyme aided extraction. Applications of enzymes in the recovery of various biomolecules such as polyphenols, oils, polysaccharides, flavours and colorants have been highlighted. Additionally, the employment of hyphenated extraction technologies can overcome some of the major drawbacks of enzyme based extraction such as longer extraction time and immoderate use of solvents. This review also includes hyphenated intensification techniques by coupling conventional methods with ultrasound, microwave, high pressure and supercritical carbon dioxide. The last section gives an insight on application of enzyme immobilization as a strategy for large scale extraction. Immobilization of enzymes on magnetic nanoparticles can be employed to enhance the operational performance of the system by multiple use of expensive enzymes making them industrially and economically feasible. Copyright © 2018 Elsevier Ltd. All rights reserved.

Enhancing Food Processing by Pulsed and High Voltage Electric Fields: Principles and Applications.

PubMed

Wang, Qijun; Li, Yifei; Sun, Da-Wen; Zhu, Zhiwei

2018-02-02

Improvements in living standards result in a growing demand for food with high quality attributes including freshness, nutrition and safety. However, current industrial processing methods rely on traditional thermal and chemical methods, such as sterilization and solvent extraction, which could induce negative effects on food quality and safety. The electric fields (EFs) involving pulsed electric fields (PEFs) and high voltage electric fields (HVEFs) have been studied and developed for assisting and enhancing various food processes. In this review, the principles and applications of pulsed and high voltage electric fields are described in details for a range of food processes, including microbial inactivation, component extraction, and winemaking, thawing and drying, freezing and enzymatic inactivation. Moreover, the advantages and limitations of electric field related technologies are discussed to foresee future developments in the food industry. This review demonstrates that electric field technology has a great potential to enhance food processing by supplementing or replacing the conventional methods employed in different food manufacturing processes. Successful industrial applications of electric field treatments have been achieved in some areas such as microbial inactivation and extraction. However, investigations of HVEFs are still in an early stage and translating the technology into industrial applications need further research efforts.

Preliminary study on activity monitoring using an android smart-watch

PubMed Central

Ahanathapillai, Vijayalakshmi; Goodwin, Zoe; James, Christopher J.

2015-01-01

The global trend for increasing life expectancy is resulting in aging populations in a number of countries. This brings to bear a pressure to provide effective care for the older population with increasing constraints on available resources. Providing care for and maintaining the independence of an older person in their own home is one way that this problem can be addressed. The EU Funded Unobtrusive Smart Environments for Independent Living (USEFIL) project is an assistive technology tool being developed to enhance independent living. As part of USEFIL, a wrist wearable unit (WWU) is being developed to monitor the physical activity (PA) of the user and integrate with the USEFIL system. The WWU is a novel application of an existing technology to the assisted living problem domain. It combines existing technologies and new algorithms to extract PA parameters for activity monitoring. The parameters that are extracted include: activity level, step count and worn state. The WWU, the algorithms that have been developed and a preliminary validation are presented. The results show that activity level can be successfully extracted, that worn state can be correctly identified and that step counts in walking data can be estimated within 3% error, using the controlled dataset. PMID:26609402

Methods from Information Extraction from LIDAR Intensity Data and Multispectral LIDAR Technology

NASA Astrophysics Data System (ADS)

Scaioni, M.; Höfle, B.; Baungarten Kersting, A. P.; Barazzetti, L.; Previtali, M.; Wujanz, D.

2018-04-01

LiDAR is a consolidated technology for topographic mapping and 3D reconstruction, which is implemented in several platforms On the other hand, the exploitation of the geometric information has been coupled by the use of laser intensity, which may provide additional data for multiple purposes. This option has been emphasized by the availability of sensors working on different wavelength, thus able to provide additional information for classification of surfaces and objects. Several applications ofmonochromatic and multi-spectral LiDAR data have been already developed in different fields: geosciences, agriculture, forestry, building and cultural heritage. The use of intensity data to extract measures of point cloud quality has been also developed. The paper would like to give an overview on the state-of-the-art of these techniques, and to present the modern technologies for the acquisition of multispectral LiDAR data. In addition, the ISPRS WG III/5 on `Information Extraction from LiDAR Intensity Data' has collected and made available a few open data sets to support scholars to do research on this field. This service is presented and data sets delivered so far as are described.

Preliminary study on activity monitoring using an android smart-watch.

PubMed

Ahanathapillai, Vijayalakshmi; Amor, James D; Goodwin, Zoe; James, Christopher J

2015-02-01

The global trend for increasing life expectancy is resulting in aging populations in a number of countries. This brings to bear a pressure to provide effective care for the older population with increasing constraints on available resources. Providing care for and maintaining the independence of an older person in their own home is one way that this problem can be addressed. The EU Funded Unobtrusive Smart Environments for Independent Living (USEFIL) project is an assistive technology tool being developed to enhance independent living. As part of USEFIL, a wrist wearable unit (WWU) is being developed to monitor the physical activity (PA) of the user and integrate with the USEFIL system. The WWU is a novel application of an existing technology to the assisted living problem domain. It combines existing technologies and new algorithms to extract PA parameters for activity monitoring. The parameters that are extracted include: activity level, step count and worn state. The WWU, the algorithms that have been developed and a preliminary validation are presented. The results show that activity level can be successfully extracted, that worn state can be correctly identified and that step counts in walking data can be estimated within 3% error, using the controlled dataset.

Ultrasound‐assisted emerging technologies for chemical processes

PubMed Central

Geertman, Rob; Wierschem, Matthias; Skiborowski, Mirko; Gielen, Bjorn; Jordens, Jeroen; John, Jinu J; Van Gerven, Tom

2018-01-01

Abstract The chemical industry has witnessed many important developments during past decades largely enabled by process intensification techniques. Some of them are already proven at commercial scale (e.g. reactive distillation) while others (e.g. ultrasound‐assisted extraction/crystallization/reaction) are on their way to becoming the next‐generation technologies. This article focuses on the advances of ultrasound (US)‐assisted technologies that could lead in the near future to significant improvements in commercial activities. The aim is to provide an authoritative discussion on US‐assisted technologies that are currently emerging from the research environment into the chemical industry, as well as give an overview of the current state‐of‐the‐art applications of US in chemical processing (e.g. enzymatic reactive distillation, crystallization of API). Sufficient information is included to allow the assessment of US‐assisted technologies and the challenges for implementation, as well as their potential for commercial applications. © 2017 The Authors. Journal of Chemical Technology & Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. PMID:29780194

Advanced Monobore Concept, Development of CFEX Self-Expanding Tubular Technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jeff Spray

2007-09-30

The Advanced Monobore Concept--CFEX{copyright} Self-Expanding Tubular Technology Development was a successfully executed fundamental research through field demonstration project. This final report is presented as a progression, according to basic technology development steps. For this project, the research and development steps used were: concept development, engineering analysis, manufacturing, testing, demonstration, and technology transfer. The CFEX{copyright} Technology Development--Advanced Monobore Concept Project successfully completed all of the steps for technology development, covering fundamental research, conceptual development, engineering design, advanced-level prototype construction, mechanical testing, and downhole demonstration. Within an approximately two year period, a partially defined, broad concept was evolved into a substantial newmore » technological area for drilling and production engineering applicable a variety of extractive industries--which was also successfully demonstrated in a test well. The demonstration achievement included an actual mono-diameter placement of two self-expanding tubulars. The fundamental result is that an economical and technically proficient means of casing any size of drilling or production well or borehole is indicated as feasible based on the results of the project. Highlighted major accomplishments during the project's Concept, Engineering, Manufacturing, Demonstration, and Technology Transfer phases, are given.« less

PHYSIOLOGICALLY BASED EXTRACTION PROCEDURE: COMPARISON OF FIVE FLUIDS

EPA Science Inventory

Traditionally, the performance of soil remediation technologies has been evaluated based on the total amount of extractable contaminants. However, some have argued that remedial treatments may alter the bioavailability as well as the mass of contaminants. For example, it has been...

ENGINEERING BULLETIN: IN SITU STEAM EXTRACTION TREATMENT

EPA Science Inventory

In situ steam extraction removes volatile and semivolatile hazardous contaminants from soil and groundwater without excavation of the hazardous waste. Waste constituents are removed in situ by the technology and are not actually treated. The use of steam enhances the stripping of...

Analyzing crime scene videos

NASA Astrophysics Data System (ADS)

Cunningham, Cindy C.; Peloquin, Tracy D.

1999-02-01

Since late 1996 the Forensic Identification Services Section of the Ontario Provincial Police has been actively involved in state-of-the-art image capture and the processing of video images extracted from crime scene videos. The benefits and problems of this technology for video analysis are discussed. All analysis is being conducted on SUN Microsystems UNIX computers, networked to a digital disk recorder that is used for video capture. The primary advantage of this system over traditional frame grabber technology is reviewed. Examples from actual cases are presented and the successes and limitations of this approach are explored. Suggestions to companies implementing security technology plans for various organizations (banks, stores, restaurants, etc.) will be made. Future directions for this work and new technologies are also discussed.

Proceedings: Fourteenth annual EPRI conference on fuel science

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-05-01

EPRI's Fourteenth Annual Contractors' Conference on Fuel Science was held on May 18--19, 1989 in Palo Alto, CA. The conference featured results of work on coal science, coal liquefaction, methanol production, and coal oil coprocessing and coal upgrading. The following topics were discussed: recent development in coal liquefaction at the Wilsonville Clean Coal Research Center; British coal's liquid solvent extraction (LSE) process; feedstock reactivity in coal/oil co-processing; utility applications for coal-oil coprocessed fuels; effect of coal rank and quality on two-stage liquefaction; organic sulfur compounds in coals; the perchloroethylene refining process of high-sulfur coals; extraction of sulfur coals; extraction ofmore » sulfur from coal; agglomeration of bituminous and subbituminous coals; solubilization of coals by cell-free extracts derived from polyporus versicolor; remediation technologies and services; preliminary results from proof-of-concept testing of heavy liquid cyclone cleaning technology; clean-up of soil contaminated with tarry/oily organics; midwest ore processing company's coal benefication technology: recent prep plant, scale and laboratory activities; combustion characterization of coal-oil agglomerate fuels; status report on the liquid phase methanol project; biomimetic catalysis; hydroxylation of C{sub 2} {minus} C{sub 3} and cycloc{sub 6} hydrocarbons with Fe cluster catalysts as models for methane monooxygenase enzyme; methanol production scenarios; and modeling studies of the BNL low temperature methanol catalyst. Individual projects are processed separately for the data bases.« less

Factors affecting registered nurses' use of medication administration technology in acute care settings: A systematic review.

PubMed

San, Tay Hui; Lin, Serena Koh Siew; Fai, Chan Moon

Information technology to aid reduction in medication errors has been encouraged over the years and one of them is the medication administration technology. It consists of the electronic Medication Administration Record, Bar-Code Medication Administration system and Automated Medication Dispensing system. Studies had examined the effectiveness and impact of this technology to reduce medication error. However, user's acceptance towards this technology has often been neglected. To date, no systematic review has been undertaken to examine the possible factors that affect nurses' use of this technology in the acute care settings. The objective of this systematic review was to explore and determine the factors that affect nurses' use of medication administration technology in the acute care settings. All quantitative studies published in English which examined factors affecting nurses' use of the medication administration technology were considered.Primary focus was on registered nurses with experience of operating medication administration technology in the acute care settings. Other healthcare personnel were excluded.This review considered studies that evaluated factors affecting nurses' use of the medication administration technology.The outcome measures of interest were the factors that affect nurses' use of the medication administration technology in the acute care settings. The search was conducted across published and unpublished databases. A search was conducted in JBI Library of Systematic Reviews, The Cochrane Library, CINAHL, MEDLINE, Scopus, ScienceDirect, Wiley InterScience, SpringerLink, PsycINFO (ovid), Web of science, ProQuest Dissertations and Theses, and MedNar. Papers selected for retrieval were assessed by two independent reviewers for methodological validity prior to inclusion in the review, using the standardised critical appraisal instruments developed by the Joanna Briggs Institute. Quantitative data were extracted from papers included in the review using a standardised data extraction tool developed by the JBI. Findings were presented in narrative summary due to heterogeneity of the study designs. Six descriptive studies were included in this review. Nurses' use of the technology can be influenced by a combination of complex and inter-related factors, such as organisational factors, and user and system characteristics. In order to successfully implement medication administration technology, system, user and organisational factors have to be collaborated concurrently.Users' needs should be accommodated when designing the system features. Prior to system implementation, institutions should consider the users' demographical characteristics and provide adequate preparations and training. A supportive culture from the institution and colleagues is also important.There is a significant need for further research in this field. Further research to discover potential factors in different settings, locations and countries are suggested. Studies to evaluate nurses' use of the technology at regular intervals are also required.

Current impact of gene technology on healthcare. A map of economic assessments.

PubMed

Rogowski, Wolf

2007-02-01

It has been claimed that gene technology will induce revolutionary changes in healthcare. This paper investigates how and to what extent these changes have been economically assessed. A generic framework was developed to distinguish between methodologically similar evaluations of healthcare technology. Methodological issues and the current state of economic evidence concerning human DNA technology were extracted from publications within these groups of evaluations. Economic evaluations of "healthcare consisting of gene technology" were identified primarily for in vitro diagnostics for hereditary disease and others for pharmacogenetics and molecular pathology. "Healthcare enabled by gene technology" is far more encompassing and includes, e.g., biotechnology drugs for which various health economic evaluations can be found. Yet here, the impact of gene technology intertwines with the impact of other technologies and is therefore hardly susceptible to evaluation. The fields of evaluation may be classified best according to the two dimensions "purpose" and "stage of development". Current evaluations cover screening, diagnostic and treatment technologies in investigational, new and established stages. Apart from prenatal screening, healthcare consisting of gene technology was cost saving only for genotype tests replacing continuous phenotype tests and for one pharmacogenetic test. Conclusive evidence of favourable cost-effectiveness ratios is available only for few conditions. Hypotheses about the impact of gene technology on healthcare must be explicit about the definition of "genetic" medicine. A general statement regarding healthcare enabled by gene technology is not possible. Based on current evidence, an era of healthcare consisting of gene technology built on widespread predictive testing is not desirable from a health economic viewpoint.

Optimization of β-cyclodextrin-based extraction of antioxidant and anti-browning activities from thyme leaves by response surface methodology.

PubMed

Favre, Leonardo Cristian; Dos Santos, Cristina; López-Fernández, María Paula; Mazzobre, María Florencia; Buera, María Del Pilar

2018-11-01

Thyme (Thymus vulgaris) has been demonstrated to extend the shelf-life of food products, being also a potential source of bioactive compounds. The aim of this research was to optimize the ultrasound assisted extraction employing β-cyclodextrin aqueous solutions as no-contaminant technology and Response Surface Methodology to obtain thyme extracts with the maximum antioxidant capacity. The optimal extraction conditions were: a solution of β-ciclodextrin 15 mM, an ultrasonic treatment time of 5.9 min at a temperature of 36.6 °C. They resulted in an extract with a polyphenolic content of 189.3 mg GAE/mL, an antioxidant activity (DPPH) of 14.8 mg GAE/mL, and ferric reducing/antioxidant power (FRAP) of 3.3 mg GAE/mL. Interestingly, the extract demonstrated to inhibit the production of Maillard browning products and can be considered a potential antiglycant agent. The obtained data is important for developing eco-friendly technologies in order to obtain natural antioxidant extracts with a potential inhibitory capacity of Maillard glycation reaction. Copyright © 2018 Elsevier Ltd. All rights reserved.

Supercritical Fluid Extraction of Metal Chelate: A Review.

PubMed

Ding, Xin; Liu, Qinli; Hou, Xiongpo; Fang, Tao

2017-03-04

Supercritical fluid extraction (SFE), as a new green extraction technology, has been used in extracting various metal species. The solubilities of chelating agents and corresponding metal chelates are the key factors which influence the efficiency of SFE. Other main properties of them such as stability and selectivity are also reviewed. The extraction mechanisms of mainly used chelating agents are explained by typical examples in this paper. This is the important aspect of SFE of metal ions. Moreover, the extraction efficiencies of metal species also depend on other factors such as temperature, pressure, extraction time and matrix effect. The two main complexation methods namely in-situ and on-line chelating SFE are described in detail. As an efficient chelating agent, tributyl phosphate-nitric acid (TBP-HNO 3 ) complex attracts much attention. The SFE of metal ions, lanthanides and actinides as well as organometallic compounds are also summarized. With the proper selection of ligands, high efficient extraction of metal species can be obtained. As an efficient sample analysis method, supercritical fluid chromatography (SFC) is introduced in this paper. Recently, the extraction method combining ionic liquids (ILs) with supercritical fluid has been becoming a novel technology for treating metal ions. The kinetics related to SFE of metal species is discussed with some specific examples.

Novel technologies applied for recovery and value addition of high value compounds from plant byproducts: A review.

PubMed

Ran, Xin-Li; Zhang, Min; Wang, Yuchuan; Adhikari, Benu

2017-09-18

Plant byproducts of food processing industry line are undervalued yet important resource. These byproducts contain large percentage of high value functional substances such as antioxidants, pectin, polyphenols and so on. Recently, many research studies concentrated on innovative technologies that promise to overcome such issues as time consuming, inefficiency, and low yield, among others, which exist in most conventional techniques. Consequently, to achieve the recovery of nutraceuticals from high added-value by-products, it is necessary to have more knowledge of these novel technologies and more importantly explore the possibility of application of these latest technologies to the recovery downstream processing. The present work will summarize state-of-the-art technological approaches concerning extraction, superfine and drying applied to plant food processing residues. Simultaneously, the application of the bioactive components originated from byproducts in food industry will also be reviewed.

Photonic quantum technologies (Presentation Recording)

NASA Astrophysics Data System (ADS)

O'Brien, Jeremy L.

2015-09-01

The impact of quantum technology will be profound and far-reaching: secure communication networks for consumers, corporations and government; precision sensors for biomedical technology and environmental monitoring; quantum simulators for the design of new materials, pharmaceuticals and clean energy devices; and ultra-powerful quantum computers for addressing otherwise impossibly large datasets for machine learning and artificial intelligence applications. However, engineering quantum systems and controlling them is an immense technological challenge: they are inherently fragile; and information extracted from a quantum system necessarily disturbs the system itself. Of the various approaches to quantum technologies, photons are particularly appealing for their low-noise properties and ease of manipulation at the single qubit level. We have developed an integrated waveguide approach to photonic quantum circuits for high performance, miniaturization and scalability. We will described our latest progress in generating, manipulating and interacting single photons in waveguide circuits on silicon chips.

NEOCHIM: An electrochemical method for environmental application

USGS Publications Warehouse

Leinz, R.W.; Hoover, D.B.; Meier, A.L.

1999-01-01

Ion migration and electroosmosis are the principal processes underlying electrokinetic remediation of hazardous wastes from soils. These processes are a response of charged species to an applied electrical current and they are accompanied by electrolysis of water at the electrodes through which the current is applied. Electrolysis results in the formation of OH- at the cathode and H+ at the anode. The current drives the OH- and H+ thus formed from the electrodes, through the soil and to the electrode of opposite charge. Introduction of OH- and H+ into the soil being treated modifies soil chemistry and can interfere with either the collection or immobilization of hazardous waste ions. The introduction of either OH- or H+ to the soil can be problematic to electrokinetic remediation but the problem caused by OH- has been the focus of most researchers. The problem has been addressed by flushing the OH- from the soil near the cathode or treating the soil with buffers. These treatments would apply as well to soils affected by H+. With the NEOCHIM technology, developed by the U.S. Geological Survey (USGS) for use as a sampling technique in exploration for buried ore deposits, OH- and H+ are retained in the inner compartment of two-compartment electrodes and are thus prevented from reaching the soil. This enables the extraction of cations and anions, including anionic forms of toxic metals such as HAsO42-. One of the principal attributes of NEOCHIM is the large volume of soil from which ions can be extracted. It is mathematically demonstrable that NEOCHIM extraction volumes can be orders of magnitude greater than volumes typically sampled in more conventional geochemical exploration methods or for environmental sampling. The technology may also be used to introduce selected ions into the soil that affect the solubility of ceratin ions present in the soil. Although field tests for mineral exploration have shown NEOCHIM extraction efficiencies of about 25-35%, laboratory experiments suggest that significantly higher efficiencies are possible. The attributes of NEOCHIM combined with relatively low cost of electrical power, indicate that the technology may be useful for remediation and monitoring of hazardous waste sites. Of particular importance is that NEOCHIM extractions affect only dissolved and electrically charged species, hence those prone to move in groundwater.The U.S. Geological Survey (USGS) has developed a technology called NEOCHIM for use as a sampling technique in exploration for buried deposits. With this technology, OH- and H+ are retained in the inner compartment of two-compartment electrodes and are thus prevented from reaching the soil. This enables the extraction of cations and anions. Laboratory experiments suggest extraction efficiencies higher than 25-35%.

Applications of satellite and marine geodesy to operations in the ocean environment

NASA Technical Reports Server (NTRS)

Fubara, D. M.; Mourad, A. G.

1975-01-01

The requirements for marine and satellite geodesy technology are assessed with emphasis on the development of marine geodesy. Various programs and missions for identification of the satellite geodesy technology applicable to marine geodesy are analyzed along with national and international marine programs to identify the roles of satellite/marine geodesy techniques for meeting the objectives of the programs and other objectives of national interest effectively. The case for marine geodesy is developed based on the extraction of requirements documented by authoritative technical industrial people, professional geodesists, government agency personnel, and applicable technology reports.

FIELD IMPLEMENTATION PLAN FOR A WILLISTON BASIN BRINE EXTRACTION AND STORAGE TEST

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hamling, John; Klapperich, Ryan; Stepan, Daniel

2016-03-31

The Energy & Environmental Research Center (EERC) successfully completed all technical work of Phase I, including development of a field implementation plan (FIP) for a brine extraction and storage test (BEST) in the North Dakota portion of the Williston Basin. This implementation plan was commissioned by the U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) as a proxy for managing formation pressure plumes and measuring/monitoring the movement of differential pressure and CO2 plumes in the subsurface for future saline CO2 storage projects. BEST comprises the demonstration and validation of active reservoir management (ARM) strategies and extracted brine treatmentmore » technologies. Two prospective commercial brine injection sites were evaluated for BEST to satisfy DOE’s goals. Ultimately, an active saltwater disposal (SWD) site, Johnsons Corner, was selected because it possesses an ideal combination of key factors making it uniquely suited to host BEST. This site is located in western North Dakota and operated by Nuverra Environmental Solutions (Nuverra), a national leader in brine handling, treatment, and injection. An integrated management approach was used to incorporate local and regional geologic characterization activities with geologic and simulation models, inform a monitoring, verification, and accounting (MVA) plan, and to conduct a risk assessment. This approach was used to design a FIP for an ARM schema and an extracted brine treatment technology test bed facility. The FIP leverages an existing pressure plume generated by two commercial SWD wells. These wells, in conjunction with a new brine extraction well, will be used to conduct the ARM schema. Results of these tests will be quantified based on their impact on the performance of the existing SWD wells and the surrounding reservoir system. Extracted brine will be injected into an underlying deep saline formation through a new injection well. The locations of proposed extraction and injection wells were selected during the Phase I efforts. These wells will be permitted as North Dakota Administrative Code Underground Injection Control Class II wells and will yield additional characterization data which will further refine the FIP in Phase II. An array of surface and downhole monitoring techniques will validate ARM performance against predictive simulation results. Infrastructure will be constructed to manage extracted fluids at the surface and provide brine to a treatment test bed facility. Treatment of extracted brine can provide a means of reducing extracted brine disposal volumes, an alternate source of water, and/or salable products for beneficial use. A test bed facility will be constructed to provide a means of demonstrating these technologies on a wide range of brine concentrations. Screening criteria based on a techno-economic and life cycle assessment were developed to select high-salinity brine treatment technologies for extended duration treatment (30–60 days) in Phase II. A detailed cost assessment determined total implementation costs for BEST of $19,901,065 million (DOE share $15,680,505). These costs are inclusive of all necessary equipment, infrastructure construction, operations and project closeout costs required to implement BEST. An ideal combination of key factors makes the Johnsons Corner site uniquely suited to be the BEST demonstration.« less

Preliminary results of sugar maple carbohydrate and growth response under vacuum and gravity sap extraction

Treesearch

Mark L. Isselhardt; Timothy D. Perkins; Abby K. van den Berg; Paul G. Schaberg

2016-01-01

Recent technological advancements have increased the amount of sugar-enriched sap that can be extracted from sugar maple (Acer saccharum). This pilot study quantified overall sugar removal and the impacts of vacuum (60 cm Hg) and gravity sap extraction on residual nonstructural carbohydrate (NSC) concentrations and on stem and twig growth. Vacuum...

Methods of downstream processing for the production of biodiesel from microalgae.

PubMed

Kim, Jungmin; Yoo, Gursong; Lee, Hansol; Lim, Juntaek; Kim, Kyochan; Kim, Chul Woong; Park, Min S; Yang, Ji-Won

2013-11-01

Despite receiving increasing attention during the last few decades, the production of microalgal biofuels is not yet sufficiently cost-effective to compete with that of petroleum-based conventional fuels. Among the steps required for the production of microalgal biofuels, the harvest of the microalgal biomass and the extraction of lipids from microalgae are two of the most expensive. In this review article, we surveyed a substantial amount of previous work in microalgal harvesting and lipid extraction to highlight recent progress in these areas. We also discuss new developments in the biodiesel conversion technology due to the importance of the connectivity of this step with the lipid extraction process. Furthermore, we propose possible future directions for technological or process improvements that will directly affect the final production costs of microalgal biomass-based biofuels. Copyright © 2013 Elsevier Inc. All rights reserved.

Technology evaluation report. Site program demonstration, resources conservation company, basic extractive sludge treatment (b. e. s. t. (trade name)), Grand Calumet River, Gary, Indiana. Volume 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wagner, T.

1993-07-01

The report summarizes the findings of an evaluation of the Basic Extractive Sludge Treatment (B.E.S.T.) solvent extraction technology developed by Resources Conservation Company (RCC). During the demonstration test, the B.E.S.T. system was used to treat composited sediments from two areas of the Grand Calumet River. Contaminant concentration reductions of 96 percent for total polynuclear aromatic hydrocarbons (PAHs) and greater than 99 percent for total polychlorinated biphenyls (PCBs) were achieved for Sediment A. Contaminant concentration reductions of greater than 99 percent for total PAHs and greater than 99 percent for total PCBs were achieved for Sediment B. Removal efficiencies in excessmore » of 98 percent were realized for both sediments for oil and grease (O G).« less

Defense Forensic Enterprise: Assessment and Status Report Personnel Accounting Extract

DTIC Science & Technology

2013-12-01

represent the opinion of the Department of the Navy. APPROVED FOR PUBLIC RELEASE. DISTRIBUTION UNLIMITED. Copies of this document can be obtained through...Roberts Director, Aviation Systems and Technology Advanced Technology and Systems Analysis REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188... Public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions

Ultrasonic Clothes Drying Technology

ScienceCinema

Patel, Viral; Momen, Ayyoub

2018-01-16

Oak Ridge National Laboratory researchers Ayyoub Momen and Viral Patel demonstrate a direct contact ultrasonic clothes dryer under development by ORNL in collaboration with General Electric (GE) Appliances. This novel approach uses high-frequency mechanical vibrations instead of heat to extract moisture as cold mist, dramatically reducing drying time and energy use. Funding for this project was competitively awarded by DOE’s Building Technologies Office in 2014.

East Europe Report, Economic and Industrial Affairs, No. 2409

DTIC Science & Technology

1983-06-09

technologically unsophisticated or because they do not correspond to the necessity for locating facilities rationally in terms of the natural and...Geological explorations and drilling in search of ore and nonmetalliferous min- eral deposits, cooperation in technology , extraction and processing...agreed to lend support and to encourage cooperation in the production of and trade in ready-to-wear clothing, knitwear , shoes, leather goods etc. 5

ecoSPEARS License Signing with Kelvin Manning

NASA Image and Video Library

2017-12-19

NASA Kennedy Space Center's Associate Director Kelvin Manning, center, signs a license agreement with the President and CEO of ecoSPEARS, which allows the company to commercially sell a soil remediation technology developed by a research team at Kennedy. The technology, known as Sorbent Polymer Extraction And Remediation System, is designed to capture and remove polychlorinated biphenyls (PCBs) from contaminated sediments in waterways and wetlands.

On the Biomimetic Design of Agile-Robot Legs

PubMed Central

Garcia, Elena; Arevalo, Juan Carlos; Muñoz, Gustavo; Gonzalez-de-Santos, Pablo

2011-01-01

The development of functional legged robots has encountered its limits in human-made actuation technology. This paper describes research on the biomimetic design of legs for agile quadrupeds. A biomimetic leg concept that extracts key principles from horse legs which are responsible for the agile and powerful locomotion of these animals is presented. The proposed biomimetic leg model defines the effective leg length, leg kinematics, limb mass distribution, actuator power, and elastic energy recovery as determinants of agile locomotion, and values for these five key elements are given. The transfer of the extracted principles to technological instantiations is analyzed in detail, considering the availability of current materials, structures and actuators. A real leg prototype has been developed following the biomimetic leg concept proposed. The actuation system is based on the hybrid use of series elasticity and magneto-rheological dampers which provides variable compliance for natural motion. From the experimental evaluation of this prototype, conclusions on the current technological barriers to achieve real functional legged robots to walk dynamically in agile locomotion are presented. PMID:22247667

Economic evaluation of technology for a new generation biofuel production using wastes.

PubMed

Koutinas, Athanasios; Kanellaki, Maria; Bekatorou, Argyro; Kandylis, Panagiotis; Pissaridi, Katerina; Dima, Agapi; Boura, Konstantina; Lappa, Katerina; Tsafrakidou, Panagiota; Stergiou, Panagiota-Yiolanda; Foukis, Athanasios; Gkini, Olga A; Papamichael, Emmanuel M

2016-01-01

An economic evaluation of an integrated technology for industrial scale new generation biofuel production using whey, vinasse, and lignocellulosic biomass as raw materials is reported. Anaerobic packed-bed bioreactors were used for organic acids production using initially synthetic media and then wastes. Butyric, lactic and acetic acid were predominately produced from vinasse, whey, and cellulose, respectively. Mass balance was calculated for a 16,000L daily production capacity. Liquid-liquid extraction was applied for recovery of the organic acids using butanol-1 as an effective extraction solvent which serves also as the alcohol for the subsequent enzyme-catalyzed esterification. The investment needed for the installation of the factory was estimated to about 1.7million€ with depreciation excepted at about 3months. For cellulosics, the installation investment was estimated to be about 7-fold higher with depreciation at about 1.5years. The proposed technology is an alternative trend in biofuel production. Copyright © 2015. Published by Elsevier Ltd.

Ultrasound-assisted oxidative desulfurization of liquid fuels and its industrial application.

PubMed

Wu, Zhilin; Ondruschka, Bernd

2010-08-01

Latest environmental regulations require a very deep desulfurization to meet the ultra-low sulfur diesel (ULSD, 15 ppm sulfur) specifications. Due to the disadvantages of hydrotreating technology on the slashing production conditions, costs and safety as well as environmental protection, the ultrasound-assisted oxidative desulfurization (UAOD) as an alternative technology has been developed. UAOD process selectively oxidizes sulfur in common thiophenes in diesel to sulfoxides and sulfones which can be removed via selective adsorption or extractant. SulphCo has successfully used a 5000 barrel/day mobile "Sonocracking" unit to duplicate on a commercial scale its proprietary process that applies ultrasonics at relatively low temperatures and pressures. The UAOD technology estimate capital costs less than half the cost of a new high-pressure hydrotreater. The physical and chemical mechanisms of UAOD process are illustrated, and the effective factors, such as ultrasonic frequency and power, oxidants, catalysts, phase-transfer agent, extractant and adsorbent, on reaction kinetics and product recovery are discussed in this review. Copyright 2009 Elsevier B.V. All rights reserved.

Parameters of Transportation of Tailings of Metals Lixiviating

NASA Astrophysics Data System (ADS)

Golik, Vladimir; Dmitrak, Yury

2017-11-01

The article shows that the change in the situation in the metals market with a steady increase in production volumes is intensified against the tendency of the transition of mining production from underground mining to underground mining for a certain group of ores. The possibility of a non-waste metals extraction from not only standard, but also from substandard raw materials, is currently provided only by technology with the lixiviating of metals from developing ores. The regular dependences of the magnitude of hydraulic resistances on the hydro-mixture velocity and its density are determined. The correct values of the experimental data convergence with the calculated values of these parameters are obtained. It is shown that the optimization of the transportation parameters of lixiviating tailings allows reducing the level of chemically dangerous pollution of the environment by leachate products. The direction of obtaining the ecological and technological effect from the use of simultaneously environmental and resource-saving technology for the extraction of the disclosed metals is indicated.

High-quality and small-capacity e-learning video featuring lecturer-superimposing PC screen images

NASA Astrophysics Data System (ADS)

Nomura, Yoshihiko; Murakami, Michinobu; Sakamoto, Ryota; Sugiura, Tokuhiro; Matsui, Hirokazu; Kato, Norihiko

2006-10-01

Information processing and communication technology are progressing quickly, and are prevailing throughout various technological fields. Therefore, the development of such technology should respond to the needs for improvement of quality in the e-learning education system. The authors propose a new video-image compression processing system that ingeniously employs the features of the lecturing scene. While dynamic lecturing scene is shot by a digital video camera, screen images are electronically stored by a PC screen image capturing software in relatively long period at a practical class. Then, a lecturer and a lecture stick are extracted from the digital video images by pattern recognition techniques, and the extracted images are superimposed on the appropriate PC screen images by off-line processing. Thus, we have succeeded to create a high-quality and small-capacity (HQ/SC) video-on-demand educational content featuring the advantages: the high quality of image sharpness, the small electronic file capacity, and the realistic lecturer motion.

Biochemical and technological studies on the production of isolated guar protein.

PubMed

Khalil, M M

2001-02-01

Guar seeds contain 32% crude protein. Therefore, attempts were made to prepare protein isolates from guar seed flour (GSF) by extraction in different media (distilled water, salt solution, alkali solution alone or in combination) followed by a precipitation at acid pH. From the four technologies adopted, mixed salt-alkali solution was found to be the most satisfactory for extraction of protein from GSF. The highest amount of product was obtained in the mixed technology along with the highest amount of protein (87.5%). Protein isolates were also nutritionally evaluated following well-established rat bioassay procedures in a comparative study with casein as standard. The protein isolates are rich in lysine but poor in sulphur-containing amino acids such as methionine and cysteine. Protein isolates obtained by mixed salt-alkali solution showed high water and oil absorption as well as good emulsifying and foaming stability. The results indicate that protein isolates can be used as a supplementary source of protein in different food industries.

On the biomimetic design of agile-robot legs.

PubMed

Garcia, Elena; Arevalo, Juan Carlos; Muñoz, Gustavo; Gonzalez-de-Santos, Pablo

2011-01-01

The development of functional legged robots has encountered its limits in human-made actuation technology. This paper describes research on the biomimetic design of legs for agile quadrupeds. A biomimetic leg concept that extracts key principles from horse legs which are responsible for the agile and powerful locomotion of these animals is presented. The proposed biomimetic leg model defines the effective leg length, leg kinematics, limb mass distribution, actuator power, and elastic energy recovery as determinants of agile locomotion, and values for these five key elements are given. The transfer of the extracted principles to technological instantiations is analyzed in detail, considering the availability of current materials, structures and actuators. A real leg prototype has been developed following the biomimetic leg concept proposed. The actuation system is based on the hybrid use of series elasticity and magneto-rheological dampers which provides variable compliance for natural motion. From the experimental evaluation of this prototype, conclusions on the current technological barriers to achieve real functional legged robots to walk dynamically in agile locomotion are presented.

RNA isolation from mammalian cells using porous polymer monoliths: an approach for high-throughput automation.

PubMed

Chatterjee, Anirban; Mirer, Paul L; Zaldivar Santamaria, Elvira; Klapperich, Catherine; Sharon, Andre; Sauer-Budge, Alexis F

2010-06-01

The life science and healthcare communities have been redefining the importance of ribonucleic acid (RNA) through the study of small molecule RNA (in RNAi/siRNA technologies), micro RNA (in cancer research and stem cell research), and mRNA (gene expression analysis for biologic drug targets). Research in this field increasingly requires efficient and high-throughput isolation techniques for RNA. Currently, several commercial kits are available for isolating RNA from cells. Although the quality and quantity of RNA yielded from these kits is sufficiently good for many purposes, limitations exist in terms of extraction efficiency from small cell populations and the ability to automate the extraction process. Traditionally, automating a process decreases the cost and personnel time while simultaneously increasing the throughput and reproducibility. As the RNA field matures, new methods for automating its extraction, especially from low cell numbers and in high throughput, are needed to achieve these improvements. The technology presented in this article is a step toward this goal. The method is based on a solid-phase extraction technology using a porous polymer monolith (PPM). A novel cell lysis approach and a larger binding surface throughout the PPM extraction column ensure a high yield from small starting samples, increasing sensitivity and reducing indirect costs in cell culture and sample storage. The method ensures a fast and simple procedure for RNA isolation from eukaryotic cells, with a high yield both in terms of quality and quantity. The technique is amenable to automation and streamlined workflow integration, with possible miniaturization of the sample handling process making it suitable for high-throughput applications.

[Complex enzyme combined with ultrasound extraction technology, physicochemical properties and antioxidant activity of Hedysarum polysaccharides].

PubMed

Yang, Xiu-Yan; Xue, Zhi-Yuan; Yang, Ya-Fei; Fang, Yao-Yao; Zhou, Xiang-Lin; Zhao, Liang-Gong; Feng, Shi-Lan

2018-06-01

In this study, complex enzymes combined with ultrasonic extraction technology（MC） were used, to select optimal extraction combinations by single factor and orthogonal test, with Hedysarum polysaccharides yield and content as the comprehensive indexes. The components, physicochemical properties and antioxidant activity of Hedysarum polysaccharides from complex enzyme combined with ultrasonic extraction（HPS-MC）and the Hedysarum polysaccharides from hot water extraction（HPS-R）were analyzed. The results showed that：complex enzymes had significant effect on the yield and content of Hedysarum polysaccharides, and the ultrasonic power could significantly improve the content of Hedysarum polysaccharides. The optimum technological parameters were as follows: complex enzyme ratio 1:1, ultrasonic power 105 W, ultrasonic time 60 min, and enzymatic hydrolysis pH 5, achieving （14.01±0.64）% and （92.45±1.47）% respectively for the yield and content of Polysaccharides. As compared with HPS-R, the molecular weight, absolute viscosity and protein content of HPS-MC were decreased, while the content of uronic acid was increased. In the antioxidant system, the concentration of polysaccharide was within the range of 1-7 g·L⁻¹; the antioxidant activity of HPS-MC was higher than that of HPS-R, and HPS-MC (80%) with the lowest molecular weight showed a significant dose effect relationship with the increase of the experimental concentration. In conclusion, MC is a simple, convenient, economical and environmentally friendly extraction technology, and the Hedysarum polysaccharides extracted by this method have obvious antioxidant activity. Copyright© by the Chinese Pharmaceutical Association.

SITE DEMONSTRATION OF THE CF SYSTEMS ORGANIC EXTRACTION PROCESS

EPA Science Inventory

The CF Systems Organic Extraction Process was used to remove PCBs from contaminated sediment dredged from the New Bedford Harbor. This work was done as part of a field demonstration under EPA's Superfund Innovative Technology Evaluation (SITE) program. The purpose of the SITE p...

Application of FTA technology to extraction of sperm DNA from mixed body fluids containing semen.

PubMed

Fujita, Yoshihiko; Kubo, Shin-ichi

2006-01-01

FTA technology is a novel method designed to simplify the collection, shipment, archiving and purification of nucleic acids from a wide variety of biological sources. In this study, we report a rapid and simple method of extracting DNA from sperm when body fluids mixed with semen were collected using FTA cards. After proteinase K digestion of the sperm and body fluid mixture, the washed pellet suspension as the sperm fraction and the concentrated supernatant as the epithelial cell fraction were respectively applied to FTA cards containing DTT. The FTA cards were dried, then directly added to a polymerase chain reaction (PCR) mix and processed by PCR. The time required from separation of the mixed fluid into sperm and epithelial origin DNA extractions was only about 2.5-3h. Furthermore, the procedure was extremely simple. It is considered that our designed DNA extraction procedure using an FTA card is available for application to routine work.

[Monitoring method of extraction process for Schisandrae Chinensis Fructus based on near infrared spectroscopy and multivariate statistical process control].

PubMed

Xu, Min; Zhang, Lei; Yue, Hong-Shui; Pang, Hong-Wei; Ye, Zheng-Liang; Ding, Li

2017-10-01

To establish an on-line monitoring method for extraction process of Schisandrae Chinensis Fructus, the formula medicinal material of Yiqi Fumai lyophilized injection by combining near infrared spectroscopy with multi-variable data analysis technology. The multivariate statistical process control (MSPC) model was established based on 5 normal batches in production and 2 test batches were monitored by PC scores, DModX and Hotelling T2 control charts. The results showed that MSPC model had a good monitoring ability for the extraction process. The application of the MSPC model to actual production process could effectively achieve on-line monitoring for extraction process of Schisandrae Chinensis Fructus, and can reflect the change of material properties in the production process in real time. This established process monitoring method could provide reference for the application of process analysis technology in the process quality control of traditional Chinese medicine injections. Copyright© by the Chinese Pharmaceutical Association.

Finger vein extraction using gradient normalization and principal curvature

NASA Astrophysics Data System (ADS)

Choi, Joon Hwan; Song, Wonseok; Kim, Taejeong; Lee, Seung-Rae; Kim, Hee Chan

2009-02-01

Finger vein authentication is a personal identification technology using finger vein images acquired by infrared imaging. It is one of the newest technologies in biometrics. Its main advantage over other biometrics is the low risk of forgery or theft, due to the fact that finger veins are not normally visible to others. Extracting finger vein patterns from infrared images is the most difficult part in finger vein authentication. Uneven illumination, varying tissues and bones, and changes in the physical conditions and the blood flow make the thickness and brightness of the same vein different in each acquisition. Accordingly, extracting finger veins at their accurate positions regardless of their thickness and brightness is necessary for accurate personal identification. For this purpose, we propose a new finger vein extraction method which is composed of gradient normalization, principal curvature calculation, and binarization. As local brightness variation has little effect on the curvature and as gradient normalization makes the curvature fairly uniform at vein pixels, our method effectively extracts finger vein patterns regardless of the vein thickness or brightness. In our experiment, the proposed method showed notable improvement as compared with the existing methods.

[Improvement of powder flowability and hygroscopicity of traditional Chinese medicine extract by surface coating modification technology].

PubMed

Zeng, Rong-Gui; Jiang, Qie-Ying; Liao, Zheng-Gen; Zhao, Guo-Wei; Luo, Yun; Luo, Juan; Lv, Dan

2016-06-01

To study the improvement of powder flowability and hygroscopicity of traditional Chinese medicine extract by surface coating modification technology. The 1% hydrophobic silica nanoparticles were used as surface modifier, and andrographis extract powder was taken as a model drug. Three different techniques were used for coating model drugs, with angle of repose, compressibility, flat angle and cohesion as the comprehensive evaluation indexes for the powder flowability. The powder particle size and the size distribution were measured by Mastersizer 2000. FEI scanning electron microscope was used to observe the surface morphology and structure of the powder. The percentage of Si element on the powder surface was measured by energy dispersive spectrometer. The hygroscopicity of powder was determined by Chinese pharmacopoeia method. All of the three techniques can improve the flowability of powder extract. In particular, hygroscopicity of extract powder can also be improved by dispersion and then high-speed mixing, which can produce a higher percentage of Si element on the powder surface. The improvement principle may be correlated with a modifier adhered to the powder surface. Copyright© by the Chinese Pharmaceutical Association.

Determination of well flat band condition in thin film FDSOI transistors using C-V measurement for accurate parameter extraction

NASA Astrophysics Data System (ADS)

Mohamad, B.; Leroux, C.; Reimbold, G.; Ghibaudo, G.

2018-01-01

For advanced gate stacks, effective work function (WFeff) and equivalent oxide thickness (EOT) are fundamental parameters for technology optimization. On FDSOI transistors, and contrary to the bulk technologies, while EOT can still be extracted at strong inversion from the typical gate-to-channel capacitance (Cgc), it is no longer the case for WFeff due to the disappearance of an observable flat band condition on capacitance characteristics. In this work, a new experimental method, the Cbg(VBG) characteristic, is proposed in order to extract the well flat band condition (VFB, W). This characteristic enables an accurate and direct evaluation of WFeff. Moreover, using the previous extraction of the gate oxide (tfox), and buried oxide (tbox) from typical capacitance characteristics (Cgc and Cbc), it allows the extraction of the channel thickness (tch). Furthermore, the measurement of the well flat band condition on Cbg(VBG) characteristics for two different Si and SiGe channel also proves the existence of a dipole at the SiGe/SiO2 interface.

Improved integral images compression based on multi-view extraction

NASA Astrophysics Data System (ADS)

Dricot, Antoine; Jung, Joel; Cagnazzo, Marco; Pesquet, Béatrice; Dufaux, Frédéric

2016-09-01

Integral imaging is a technology based on plenoptic photography that captures and samples the light-field of a scene through a micro-lens array. It provides views of the scene from several angles and therefore is foreseen as a key technology for future immersive video applications. However, integral images have a large resolution and a structure based on micro-images which is challenging to encode. A compression scheme for integral images based on view extraction has previously been proposed, with average BD-rate gains of 15.7% (up to 31.3%) reported over HEVC when using one single extracted view. As the efficiency of the scheme depends on a tradeoff between the bitrate required to encode the view and the quality of the image reconstructed from the view, it is proposed to increase the number of extracted views. Several configurations are tested with different positions and different number of extracted views. Compression efficiency is increased with average BD-rate gains of 22.2% (up to 31.1%) reported over the HEVC anchor, with a realistic runtime increase.

Big data; sensor networks and remotely-sensed data for mapping; feature extraction from lidar

NASA Astrophysics Data System (ADS)

Tlhabano, Lorato

2018-05-01

Unmanned aerial vehicles (UAVs) can be used for mapping in the close range domain, combining aerial and terrestrial photogrammetry and now the emergence of affordable platforms to carry these technologies has opened up new opportunities for mapping and modeling cadastral boundaries. At the current state mainly low cost UAVs fitted with sensors are used in mapping projects with low budgets, the amount of data produced by the UAVs can be enormous hence the need for big data techniques' and concepts. The past couple of years have witnessed the dramatic rise of low-cost UAVs fitted with high tech Lidar sensors and as such the UAVS have now reached a level of practical reliability and professionalism which allow the use of these systems as mapping platforms. UAV based mapping provides not only the required accuracy with respect to cadastral laws and policies as well as requirements for feature extraction from the data sets and maps produced, UAVs are also competitive to other measurement technologies in terms of economic aspects. In the following an overview on how the various technologies of UAVs, big data concepts and lidar sensor technologies can work together to revolutionize cadastral mapping particularly in Africa and as a test case Botswana in particular will be used to investigate these technologies. These technologies can be combined to efficiently provide cadastral mapping in difficult to reach areas and over large areas of land similar to the Land Administration Procedures, Capacity and Systems (LAPCAS) exercise which was recently undertaken by the Botswana government, we will show how the uses of UAVS fitted with lidar sensor and utilizing big data concepts could have reduced not only costs and time for our government but also how UAVS could have provided more detailed cadastral maps.

Industrial Applications of High Power Ultrasonics

NASA Astrophysics Data System (ADS)

Patist, Alex; Bates, Darren

Since the change of the millennium, high-power ultrasound has become an alternative food processing technology applicable to large-scale commercial applications such as emulsification, homogenization, extraction, crystallization, dewatering, low-temperature pasteurization, degassing, defoaming, activation and inactivation of enzymes, particle size reduction, extrusion, and viscosity alteration. This new focus can be attributed to significant improvements in equipment design and efficiency during the late 1990 s. Like most innovative food processing technologies, high-power ultrasonics is not an off-the-shelf technology, and thus requires careful development and scale-up for each and every application. The objective of this chapter is to present examples of ultrasonic applications that have been successful at the commercialization stage, advantages, and limitations, as well as key learnings from scaling up an innovative food technology in general.

Optimization of Supercritical Carbon Dioxide Extraction of Eucommia ulmoides Seed Oil and Quality Evaluation of the Oil.

PubMed

Zhang, Zhen-Shan; Liu, Yu-Lan; Che, Li-Ming

2018-03-01

Supercritical carbon dioxide extraction (SC-CO 2 ) technology was used to extract oil from Eucommia ulmoides seed. The optimum conditions and significant parameters in SC-CO 2 were obtained using response surface methodology (RSM). The qualities of the extracted oil were evaluated by physicochemical properties, fatty acid composition, vitamin E composition. It was found that the optimum extraction parameters were at pressure of 37 MPa, temperature of 40°C, extraction time of 125 min and CO 2 flow rate of 2.6 SL/min. Pressure, temperature and time were identified as significant parameter effecting on extraction yield. The importance of evaluated parameters decreased in the order of pressure > extraction time > temperature > CO 2 flow rate. GC analysis indicated that E. ulmoides seed oil contained about 61% of linolenic acid and its fatty acid composition was similar with that of flaxseed oil and perilla oil. The content and composition of vitamin E was determined using HPLC. The E. ulmoides seed oil was rich in vitamin E (190.72 mg/100 g), the predominant vitamin E isomers were γ- tocopherol and δ- tocopherol, which accounted for 70.87% and 24.81% of the total vitamin E, respectively. The high yield and good physicochemical properties of extracted oil support the notion that SC-CO 2 technology is an effective technique for extracting oil from E. ulmoides seed.

Liquefaction for cataract extraction

PubMed Central

Labiris, Georgios; Toli, Aspasia; Polychroni, Damaskini; Gkika, Maria; Angelonias, Dimitrios; Kozobolis, Vassilios P.

2016-01-01

A systematic review of the recent literature regarding the implementation of the liquefaction in cataract surgery and its short-term and long-term outcomes in various parameters that affect the quality of patients' life, including visual rehabilitation and possible complications was performed based on the PubMed, Medline, Nature and the American Academy of Ophthalmology databases in November 2013 and data from 14 comparative studies were included in this narrative review. Liquefaction is an innovative technology for cataract extraction that uses micropulses of balanced salt solution to liquefy the lens nucleus. Most studies reported that liquefaction is a reliable technology for mild to moderate cataracts, while fragmentation difficulties may be encountered with harder nuclei. PMID:26949656

[Application of hyper-spectral remote sensing technology in environmental protection].

PubMed

Zhao, Shao-Hua; Zhang, Feng; Wang, Qiao; Yao, Yun-Jun; Wang, Zhong-Ting; You, Dai-An

2013-12-01

Hyper-spectral remote sensing (RS) technology has been widely used in environmental protection. The present work introduces its recent application in the RS monitoring of pollution gas, green-house gas, algal bloom, water quality of catch water environment, safety of drinking water sources, biodiversity, vegetation classification, soil pollution, and so on. Finally, issues such as scarce hyper-spectral satellites, the limits of data processing and information extract are related. Some proposals are also presented, including developing subsequent satellites of HJ-1 satellite with differential optical absorption spectroscopy, greenhouse gas spectroscopy and hyper-spectral imager, strengthening the study of hyper-spectral data processing and information extraction, and promoting the construction of environmental application system.

Latest Progress of Fault Detection and Localization in Complex Electrical Engineering

NASA Astrophysics Data System (ADS)

Zhao, Zheng; Wang, Can; Zhang, Yagang; Sun, Yi

2014-01-01

In the researches of complex electrical engineering, efficient fault detection and localization schemes are essential to quickly detect and locate faults so that appropriate and timely corrective mitigating and maintenance actions can be taken. In this paper, under the current measurement precision of PMU, we will put forward a new type of fault detection and localization technology based on fault factor feature extraction. Lots of simulating experiments indicate that, although there are disturbances of white Gaussian stochastic noise, based on fault factor feature extraction principal, the fault detection and localization results are still accurate and reliable, which also identifies that the fault detection and localization technology has strong anti-interference ability and great redundancy.

Longwall top coal caving (LTCC) mining technologies with roof softening by hydraulic fracturing method

NASA Astrophysics Data System (ADS)

Klishin, V.; Nikitenko, S.; Opruk, G.

2018-05-01

The paper discusses advanced top coal caving technologies for thick coal seams and addresses some issues of incomplete coal extraction, which can result in the environmental damage, landscape change, air and water pollution and endogenous fires. The authors put forward a fundamentally new, having no equivalent and ecology-friendly method to difficult-to-cave roof coal – directional hydraulic fracturing and nonexplosive disintegration.

Phytoremediation of Excavation in Eastern Siberia

NASA Astrophysics Data System (ADS)

Timofeeva, S. S.; Zhmurova, T. M.

2017-04-01

The paper deals with prospects and applicability of phytoremediation technology in the conditions of Eastern Siberia as applied to gypsum stone extraction of Zalarinsky deposit in Irkutsk region. It analyses dust intensity for different technological processes of the deposit and evaluates the dust loading on the workers of the deposit. The selection of plantings that have potential to neutralize the dust loading produced by the plot “Severniy” is carried out.

First Complete Genomic Sequence of a Rabies Virus from the Republic of Tajikistan Obtained Directly from a Flinders Technology Associates Card

PubMed Central

Goharriz, H.; Marston, D. A.; Sharifzoda, F.; Ellis, R. J.; Horton, D. L.; Khakimov, T.; Whatmore, A.; Khamroev, K.; Makhmadshoev, A. N.; Bazarov, M.; Fooks, A. R.

2017-01-01

ABSTRACT A brain homogenate derived from a rabid dog in the district of Tojikobod, Republic of Tajikistan, was applied to a Flinders Technology Associates (FTA) card. A full-genome sequence of rabies virus (RABV) was generated from the FTA card directly without extraction, demonstrating the utility of these cards for readily obtaining genetic data. PMID:28684566

First Complete Genomic Sequence of a Rabies Virus from the Republic of Tajikistan Obtained Directly from a Flinders Technology Associates Card.

PubMed

Goharriz, H; Marston, D A; Sharifzoda, F; Ellis, R J; Horton, D L; Khakimov, T; Whatmore, A; Khamroev, K; Makhmadshoev, A N; Bazarov, M; Fooks, A R; Banyard, A C

2017-07-06

A brain homogenate derived from a rabid dog in the district of Tojikobod, Republic of Tajikistan, was applied to a Flinders Technology Associates (FTA) card. A full-genome sequence of rabies virus (RABV) was generated from the FTA card directly without extraction, demonstrating the utility of these cards for readily obtaining genetic data. © Crown copyright 2017.

Reliable Electronic Text: The Elusive Prerequisite for a Host of Human Language Technologies

DTIC Science & Technology

2010-09-30

is not always the case—for example, ligatures in Latin-fonts, and glyphs in Arabic fonts (King, 2008; Carrier, 2009). This complexity, and others...such effects can render electronic text useless for natural language processing ( NLP ). Typically, file converters do not expose the details of the...the many component NLP technologies typically used inside information extraction and text categorization applications, such as tokenization, part-of

A New Formulation for the Removal and Remediation of Polychlorinated Biphenyls in Painted Structures

NASA Technical Reports Server (NTRS)

Quinn, Jacqueline; Brooks, Kathleen; Geiger, Cherie; Clausen, Christian

2009-01-01

This new technology report will describe the laboratory development of a new and innovative solution for the removal and destruction of PCBs found in painted structures or within the binding or caulking material on structures. The technology incorporates a Bimetallic Treatment System (BTS) that extracts and degrades only the PCBs found on the facilities, leaving in most cases the structure virtually unaltered.

Assessment of the use of space technology in the monitoring of oil spills and ocean pollution: Executive summary

NASA Technical Reports Server (NTRS)

Alvarado, U. R. (Editor)

1980-01-01

The adequacy of current technology in terms of stage of maturity, of sensing, support systems, and information extraction was assessed relative to oil spills, waste pollution, and inputs to pollution trajectory models. Needs for advanced techniques are defined and the characteristics of a future satellite system are determined based on the requirements of U.S. agencies involved in pollution monitoring.

Terra Vac In Situ Vacuum Extraction System: Applications Analysis Report

EPA Science Inventory

This document is an evaluation of the Terra Vac in situ vacuum extraction system and its applicability as a treatment method for waste site cleanup. This report analyzes the results from the Superfund Innovative Technology Evaluation (SITE) Program’s 56-day demonstration at t...

How PNNL Extracts Rare Earth Elements from Geothermal Brine

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2016-07-12

By looking at a problem at a nanoscale level, PNNL researchers are developing an economic way to extract valuable rare earth elements from geothermal fluids. This novel approach may help meet the high demand for rare earth elements that are used in many clean energy technologies.

Using Technology to Deliver Mental Health Services to Children and Youth: A Scoping Review

PubMed Central

Boydell, Katherine M.; Hodgins, Michael; Pignatiello, Antonio; Teshima, John; Edwards, Helen; Willis, David

2014-01-01

Objective: To conduct a scoping review on the use of technology to deliver mental health services to children and youth in order to identify the breadth of peer-reviewed literature, summarize findings and identify gaps. Method: A literature database search identified 126 original studies meeting criteria for review. Descriptive numerical summary and thematic analyses were conducted. Two reviewers independently extracted data. Results: Studies were characterized by diverse technologies including videoconferencing, telephone and mobile phone applications and Internet-based applications such as email, web sites and CD-ROMs. Conclusion: The use of technologies plays a major role in the delivery of mental health services and supports to children and youth in providing prevention, assessment, diagnosis, counseling and treatment programs. Strategies are growing exponentially on a global basis, thus it is critical to study the impact of these technologies on child and youth mental health service delivery. An in-depth review and synthesis of the quality of findings of studies on effectiveness of the use of technologies in service delivery are also warranted. A full systematic review would provide that opportunity. PMID:24872824

Using technology to deliver mental health services to children and youth: a scoping review.

PubMed

Boydell, Katherine M; Hodgins, Michael; Pignatiello, Antonio; Teshima, John; Edwards, Helen; Willis, David

2014-05-01

To conduct a scoping review on the use of technology to deliver mental health services to children and youth in order to identify the breadth of peer-reviewed literature, summarize findings and identify gaps. A literature database search identified 126 original studies meeting criteria for review. Descriptive numerical summary and thematic analyses were conducted. Two reviewers independently extracted data. Studies were characterized by diverse technologies including videoconferencing, telephone and mobile phone applications and Internet-based applications such as email, web sites and CD-ROMs. The use of technologies plays a major role in the delivery of mental health services and supports to children and youth in providing prevention, assessment, diagnosis, counseling and treatment programs. Strategies are growing exponentially on a global basis, thus it is critical to study the impact of these technologies on child and youth mental health service delivery. An in-depth review and synthesis of the quality of findings of studies on effectiveness of the use of technologies in service delivery are also warranted. A full systematic review would provide that opportunity.

Anticancer patent landscape and technology assessment of Indian public-funded research institutes and organizations.

PubMed

Dara, Ajay; Sangamwar, Abhay T

2014-08-01

This review discusses the various drug therapeutic targets and latest technologies of anticancer patents from 10 Indian public-funded research organizations covering more than 150 esteemed institutes. We have identified and reported the leading assignee and inventors along with their collaboration network and, thereby, have analyzed the various patent trends, geographical distributions, citation maps, Derwent World Patents Index, international patent classification analysis and the like. This article provides the insights of 1905 patent documents from 191 families and discusses in-depth anticancer technology through categorization studies at the level of drug discovery, drug development and treatment and diagnosis. In addition, various cancer targets were correlated with recent technologies so as to identify the white spaces for upcoming technologies. Over a period of 13 years (1990 - 2013) the main focus of Indian cancer research was in the field of synthetic chemistry and natural extracts followed by the pharmaceutical compositions and combinations, whereas, the white spaces for future cancer remedy were identified from research in the areas of cancer stem cell lines, vaccines, gene therapy, nano formulations with targeted drug delivery systems as core and latest technologies.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kaplan, Ruth; Mamrosh, Darryl; Salih, Hafiz H.

Brine extraction is a promising strategy for the management of increased reservoir pressure, resulting from carbon dioxide (CO 2) injection in deep saline reservoirs. The extracted brines usually have high concentrations of total dissolved solids (TDS) and various contaminants, and require proper disposal or treatment. In this article, first by conducting a critical review, we evaluate the applicability, limits, and advantages or challenges of various commercially available and emerging desalination technologies that can potentially be employed to treat the highly saline brine (with TDS values >70.000 ppm) and those that are applicable to a ~200,000 ppm TDS brine extracted frommore » the Mt. Simon Sandstone, a potential CO 2 storage site in Illinois, USA. Based on the side-by-side comparison of technologies, evaporators are selected as the most suitable existing technology for treating Mt. Simon brine. Process simulations are then conducted for a conceptual design for desalination of 454 m 3/h (2000 gpm) pretreated brine for near-zero liquid discharge by multi-effect evaporators. In conclusion, the thermal energy demand is estimated at 246kWh perm 3 of recoveredwater, ofwhich 212kWh/m 3 is required for multiple-effect evaporation and the remainder for salt drying. The process also requires additional electrical power of ~2 kWh/m 3.« less

Recent advances in enzyme extraction strategies: A comprehensive review.

PubMed

Nadar, Shamraja S; Pawar, Rohini G; Rathod, Virendra K

2017-08-01

The increasing interest of industrial enzymes demands for development of new downstream strategies for maximizing enzyme recovery. The significant efforts have been focused on the development of newly adapted technologies to purify enzymes in catalytically active form. Recently, an aqueous two phase system (ATPS) is emerged as powerful tools for efficient extraction and purification of enzymes due to their versatility, lower cost, process integration capability and easy scale-up. The present review gives an overview of effect of parameters such as tie line length, pH, neutral salts, properties of polymer and salt involved in traditional polymer/polymer and polymer/salt ATPS for enzyme recovery. Further, advanced ATPS have been developed based on alcohols, surfactants, micellar compounds to avoid tedious recovery steps for getting desired enzyme. In order to improve the selectivity and efficiency of ATPS, recent approaches of conventional ATPS combined with different techniques like affinity ligands, ionic liquids, thermoseparating polymers and microfluidic device based ATPS have been reviewed. Moreover, three phase partitioning is also highlighted for enzymes enrichment as a blooming technology for efficiently integrated bioseparation techniques. At the end, it includes an overview of CLEAs technology and organic-inorganic nanoflowers preparation as novel strategies for simultaneous extraction, purification and immobilization of enzymes. Copyright © 2017 Elsevier B.V. All rights reserved.

[Optimization of vacuum belt drying process of Gardeniae Fructus in Reduning injection by Box-Behnken design-response surface methodology].

PubMed

Huang, Dao-sheng; Shi, Wei; Han, Lei; Sun, Ke; Chen, Guang-bo; Wu Jian-xiong; Xu, Gui-hong; Bi, Yu-an; Wang, Zhen-zhong; Xiao, Wei

2015-06-01

To optimize the belt drying process conditions optimization of Gardeniae Fructus extract from Reduning injection by Box-Behnken design-response surface methodology, on the basis of single factor experiment, a three-factor and three-level Box-Behnken experimental design was employed to optimize the drying technology of Gardeniae Fructus extract from Reduning injection. With drying temperature, drying time, feeding speed as independent variables and the content of geniposide as dependent variable, the experimental data were fitted to a second order polynomial equation, establishing the mathematical relationship between the content of geniposide and respective variables. With the experimental data analyzed by Design-Expert 8. 0. 6, the optimal drying parameter was as follows: the drying temperature was 98.5 degrees C , the drying time was 89 min, the feeding speed was 99.8 r x min(-1). Three verification experiments were taked under this technology and the measured average content of geniposide was 564. 108 mg x g(-1), which was close to the model prediction: 563. 307 mg x g(-1). According to the verification test, the Gardeniae Fructus belt drying process is steady and feasible. So single factor experiments combined with response surface method (RSM) could be used to optimize the drying technology of Reduning injection Gardenia extract.

Extraction of Volatiles from Regolith or Soil on Mars, the Moon, and Asteroids

NASA Technical Reports Server (NTRS)

Linne, Diane; Kleinhenz, Julie; Trunek, Andrew; Hoffman, Stephen; Collins, Jacob

2017-01-01

NASA's Advanced Exploration Systems ISRU Technology Project is evaluating concepts to extract water from all resource types Near-term objectives: Produce high-fidelity mass, power, and volume estimates for mining and processing systems Identify critical challenges for development focus Begin demonstration of component and subsystem technologies in relevant environment Several processor types: Closed processors either partially or completely sealed during processing Open air processors operates at Mars ambient conditions In-situ processors Extract product directly without excavation of raw resource Design features Elimination of sweep gas reduces dust particles in water condensate Pressure maintained by height of soil in hopper Model developed to evaluate key design parameters Geometry: conveyor diameter, screw diameter, shaft diameter, flight spacing and pitch Operational: screw speed vs. screw length (residence time) Thermal: Heat flux, heat transfer to soil Testing to demonstrate feasibility and performance Agglomeration, clogging Pressure rise forced flow to condenser.

Latent Dirichlet Allocation (LDA) Model and kNN Algorithm to Classify Research Project Selection

NASA Astrophysics Data System (ADS)

Safi’ie, M. A.; Utami, E.; Fatta, H. A.

2018-03-01

Universitas Sebelas Maret has a teaching staff more than 1500 people, and one of its tasks is to carry out research. In the other side, the funding support for research and service is limited, so there is need to be evaluated to determine the Research proposal submission and devotion on society (P2M). At the selection stage, research proposal documents are collected as unstructured data and the data stored is very large. To extract information contained in the documents therein required text mining technology. This technology applied to gain knowledge to the documents by automating the information extraction. In this articles we use Latent Dirichlet Allocation (LDA) to the documents as a model in feature extraction process, to get terms that represent its documents. Hereafter we use k-Nearest Neighbour (kNN) algorithm to classify the documents based on its terms.

Technology evaluation report. Site program demonstration, resources conservation company, basic extractive sludge treatment (b. e. s. t. (trade name)), Grand Calumet River, Gary, Indiana. Volume 2. Part 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wagner, T.

1993-07-01

The report summarizes the findings of an evaluation of the Basic Extractive Sludge Treatment (B.E.S.T.) solvent extraction technology developed by Resources Conservation Company (RCC). During the demonstration test, the B.E.S.T. system was used to treat composited sediments from two areas of the Grand Calumet River. Contaminant concentration reductions of 96 percent for total polynuclear aromatic hydrocarbons (PAHs) and greater than 99 percent for total polychlorinated biphenyls (PCBs) were achieved for Sediment A. Contaminant concentration reductions of greater than 99 percent for total PAHs and greater than 99 percent for total PCBs were achieved for Sediment B. Removal efficiencies in excessmore » of 98 percent were realized for both sediments for oil and grease (O G).« less

Technology evaluation report. Site program demonstration, resources conservation company, basic extractive sludge treatment (b. e. s. t. (trade name)), Grant Calumet River, Gary, Indiana. Volume 2. Part 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wagner, T.

1993-07-01

The report summarizes the findings of an evaluation of the Basic Extractive Sludge Treatment (B.E.S.T.) solvent extraction technology developed by Resources Conservation Company (RCC). During the demonstration test, the B.E.S.T. system was used to treat composited sediments from two areas of the Grand Calumet River. Contaminant concentration reductions of 96 percent for total polynuclear aromatic hydrocarbons (PAHs) and greater than 99 percent for total polychlorinated biphenyls (PCBs) were achieved for Sediment A. Contaminant concentration reductions of greater than 99 percent for total PAHs and greater than 99 percent for total PCBs were achieved for Sediment B. Removal efficiencies in excessmore » of 98 percent were realized for both sediments for oil and grease (O G).« less

Extraction of rubidium from natural resources

NASA Astrophysics Data System (ADS)

Ertan, Bengü

2017-04-01

Rubidium is a rare alkali metal in the first group of periodic table. It has some exclusive properties like softness, ductility, malleability, strong chemical and photo-emissive activity, low melting point, easy ionization. So it is used many of applications such that optical and laser technology, electronics, telecommunications, biomedical, space technology, academic research especially quantum mechanics-based computing devices. Attention of rubidium in relation to its uses will increase in the near future. Rubidium does not have any mineral that is the main component. It is produced as minor quantities from lithium or cesium-rich minerals and natural brines. However, there are a few researches on the extraction of rubidium from mine tailings. It is difficult extraction or concentration of rubidium from these resources. Because they require a series of physical and chemical treatments and cost expensive. Efficient, cheap and friendly of environment methods for the recovery of this metal are being investigated.

Technologies for Decreasing Mining Losses

NASA Astrophysics Data System (ADS)

Valgma, Ingo; Väizene, Vivika; Kolats, Margit; Saarnak, Martin

2013-12-01

In case of stratified deposits like oil shale deposit in Estonia, mining losses depend on mining technologies. Current research focuses on extraction and separation possibilities of mineral resources. Selective mining, selective crushing and separation tests have been performed, showing possibilities of decreasing mining losses. Rock crushing and screening process simulations were used for optimizing rock fractions. In addition mine backfilling, fine separation, and optimized drilling and blasting have been analyzed. All tested methods show potential and depend on mineral usage. Usage in addition depends on the utilization technology. The questions like stability of the material flow and influences of the quality fluctuations to the final yield are raised.

Development of Plant Control Diagnosis Technology and Increasing Its Applications

NASA Astrophysics Data System (ADS)

Kugemoto, Hidekazu; Yoshimura, Satoshi; Hashizume, Satoru; Kageyama, Takashi; Yamamoto, Toru

A plant control diagnosis technology was developed to improve the performance of plant-wide control and maintain high productivity of plants. The control performance diagnosis system containing this technology picks out the poor performance loop, analyzes the cause, and outputs the result on the Web page. Meanwhile, the PID tuning tool is used to tune extracted loops from the control performance diagnosis system. It has an advantage of tuning safely without process changes. These systems are powerful tools to do Kaizen (continuous improvement efforts) step by step, coordinating with the operator. This paper describes a practical technique regarding the diagnosis system and its industrial applications.

Thermal power systems, point-focusing distributed receiver technology project. Volume 2: Detailed report

NASA Technical Reports Server (NTRS)

Lucas, J.

1979-01-01

Thermal or electrical power from the sun's radiated energy through Point-Focusing Distributed Receiver technology is the goal of this Project. The energy thus produced must be economically competitive with other sources. The Project supports the industrial development of technology and hardware for extracting energy from solar power to achieve the stated goal. Present studies are working to concentrate the solar energy through mirrors or lenses, to a working fluid or gas, and through a power converter change to an energy source useful to man. Rankine-cycle and Brayton-cycle engines are currently being developed as the most promising energy converters for our near future needs.

Current mHealth Technologies for Physical Activity Assessment and Promotion

PubMed Central

O’Reilly, Gillian A.; Spruijt-Metz, Donna

2014-01-01

Context Novel mobile assessment and intervention capabilities are changing the face of physical activity (PA) research. A comprehensive systematic review of how mobile technology has been used for measuring PA and promoting PA behavior change is needed. Evidence acquisition Article collection was conducted using six databases from February to June 2012 with search terms related to mobile technology and PA. Articles that described the use of mobile technologies for PA assessment, sedentary behavior assessment, and/or interventions for PA behavior change were included. Articles were screened for inclusion and study information was extracted. Evidence synthesis Analyses were conducted from June to September 2012. Mobile phone–based journals and questionnaires, short message service (SMS) prompts, and on-body PA sensing systems were the mobile technologies most utilized. Results indicate that mobile journals and questionnaires are effective PA self-report measurement tools. Intervention studies that reported successful promotion of PA behavior change employed SMS communication, mobile journaling, or both SMS and mobile journaling. Conclusions mHealth technologies are increasingly being employed to assess and intervene on PA in clinical, epidemiologic, and intervention research. The wide variations in technologies used and outcomes measured limit comparability across studies, and hamper identification of the most promising technologies. Further, the pace of technologic advancement currently outstrips that of scientific inquiry. New adaptive, sequential research designs that take advantage of ongoing technology development are needed. At the same time, scientific norms must shift to accept “smart,” adaptive, iterative, evidence-based assessment and intervention technologies that will, by nature, improve during implementation. PMID:24050427

Current mHealth technologies for physical activity assessment and promotion.

PubMed

O'Reilly, Gillian A; Spruijt-Metz, Donna

2013-10-01

Novel mobile assessment and intervention capabilities are changing the face of physical activity (PA) research. A comprehensive systematic review of how mobile technology has been used for measuring PA and promoting PA behavior change is needed. Article collection was conducted using six databases from February to June 2012 with search terms related to mobile technology and PA. Articles that described the use of mobile technologies for PA assessment, sedentary behavior assessment, and/or interventions for PA behavior change were included. Articles were screened for inclusion and study information was extracted. Analyses were conducted from June to September 2012. Mobile phone-based journals and questionnaires, short message service (SMS) prompts, and on-body PA sensing systems were the mobile technologies most utilized. Results indicate that mobile journals and questionnaires are effective PA self-report measurement tools. Intervention studies that reported successful promotion of PA behavior change employed SMS communication, mobile journaling, or both SMS and mobile journaling. mHealth technologies are increasingly being employed to assess and intervene on PA in clinical, epidemiologic, and intervention research. The wide variations in technologies used and outcomes measured limit comparability across studies, and hamper identification of the most promising technologies. Further, the pace of technologic advancement currently outstrips that of scientific inquiry. New adaptive, sequential research designs that take advantage of ongoing technology development are needed. At the same time, scientific norms must shift to accept "smart," adaptive, iterative, evidence-based assessment and intervention technologies that will, by nature, improve during implementation. © 2013 American Journal of Preventive Medicine.

A novel approach for the efficient extraction of silybin from milk thistle fruits.

PubMed

Tan, Caihong; Xu, Xianrong; Shang, Yaqi; Fu, Xianli; Xia, Guohua; Yang, Huan

2014-10-01

Milk Thistle fruit is an important herb popularly consumed worldwide for a very long time. Silybin is the main bioactive constituent of the herb, and it has been approved by US Food and Drug Administration (FDA) as a medicine to treat liver diseases. Presently, using conventional technology, the meal of Milk Thistle fruit is used as the raw material to extract silybin. To investigate the necessity of detaching husk from kernel of the herb and also to propose a novel approach to enhance the extraction technology in pharmaceutical practices. The husk of Milk Thistle fruit was detached from the kernel of the herb using an automatic huller specially designed for this application. The husk and the meal of Milk Thistle fruit was subsequently refluxed, separately, with production rate of silybin as index for comparison of their extraction effect. The highest production rate was achieved under optimized condition. The husk was extracted 2 times (3 hrs each) using ethyl acetate, and the ratio of solvent to raw material was 8:1. The extract was allowed to be crystallized out. The separation of kernel from the husk of Milk Thistle fruit and using only the husk as raw material can largely enhance the extraction of silybin.

Peroxidase extraction from jicama skin peels for phenol removal

NASA Astrophysics Data System (ADS)

Chiong, T.; Lau, S. Y.; Khor, E. H.; Danquah, M. K.

2016-06-01

Phenol and its derivatives exist in various types of industrial effluents, and are known to be harmful to aquatic lives even at low concentrations. Conventional treatment technologies for phenol removal are challenged with long retention time, high energy consumption and process cost. Enzymatic treatment has emerged as an alternative technology for phenol removal from wastewater. These enzymes interact with aromatic compounds including phenols in the presence of hydrogen peroxide, forming free radicals which polymerize spontaneously to produce insoluble phenolic polymers. This work aims to extract peroxidase from agricultural wastes materials and establish its application for phenol removal. Peroxidase was extracted from jicama skin peels under varying extraction conditions of pH, sample-to-buffer ratio (w/v %) and temperature. Experimental results showed that extraction process conducted at pH 10, 40% w/v and 25oC demonstrated a peroxidase activity of 0.79 U/mL. Elevated temperatures slightly enhanced the peroxidase activities. Jicama peroxidase extracted at optimum extraction conditions demonstrated a phenol removal efficiency of 87.5% at pH 7. Phenol removal efficiency was ∼ 97% in the range of 30 - 40oC, and H2O2 dosage has to be kept below 100 mM for maximum removal under phenol concentration tested.

Apache Clinical Text and Knowledge Extraction System (cTAKES) | Informatics Technology for Cancer Research (ITCR)

Cancer.gov

The tool extracts deep phenotypic information from the clinical narrative at the document-, episode-, and patient-level. The final output is FHIR compliant patient-level phenotypic summary which can be consumed by research warehouses or the DeepPhe native visualization tool.

Assessment of Nigella sativa extract as a potential antibiotic alternative feed supplement for weaned swine

USDA-ARS?s Scientific Manuscript database

New technologies are needed to help livestock producers maintain health and wellbeing of their animals while minimizing risks of disseminating antimicrobial resistant bacteria to humans or animals. Nigella sativa (NS) is a plant containing bioactive constituents, such as thymoquinone. Extracts of ...

Emerging Technology Summary. ACID EXTRACTION TREATMENT SYSTEM FOR TREATMENT OF METAL CONTAMINATED SOILS

EPA Science Inventory

The Acid Extraction Treatment System (AETS) is intended to reduce the concentrations and/or teachability of heavy metals in contaminated soils so the soil can be returned to the site from which it originated. The objective of the project was to determine the effectiveness and com...

EPA SITE DEMONSTRATION OF THE TERRA VAC IN SITU VACUUM EXTRACTION PROCESS IN GROVELAND, MASSACHUSETTS

EPA Science Inventory

This paper presents an EPA evaluation of the patented Terra Vac, Inc.'s in situ vacuum extraction process that was field-demonstrated on a trichloroethylene (TCE) contaminated soil in Groveland, MA, under the EPA Superfund Innovative Technology Evaluation (SITE) program. he Terra...

Extraction Techniques for Polycyclic Aromatic Hydrocarbons in Soils

PubMed Central

Lau, E. V.; Gan, S.; Ng, H. K.

2010-01-01

This paper aims to provide a review of the analytical extraction techniques for polycyclic aromatic hydrocarbons (PAHs) in soils. The extraction technologies described here include Soxhlet extraction, ultrasonic and mechanical agitation, accelerated solvent extraction, supercritical and subcritical fluid extraction, microwave-assisted extraction, solid phase extraction and microextraction, thermal desorption and flash pyrolysis, as well as fluidised-bed extraction. The influencing factors in the extraction of PAHs from soil such as temperature, type of solvent, soil moisture, and other soil characteristics are also discussed. The paper concludes with a review of the models used to describe the kinetics of PAH desorption from soils during solvent extraction. PMID:20396670

Landmarks in the historical development of twenty first century food processing technologies.

PubMed

Misra, N N; Koubaa, Mohamed; Roohinejad, Shahin; Juliano, Pablo; Alpas, Hami; Inácio, Rita S; Saraiva, Jorge A; Barba, Francisco J

2017-07-01

Over a course of centuries, various food processing technologies have been explored and implemented to provide safe, fresher-tasting and nutritive food products. Among these technologies, application of emerging food processes (e.g., cold plasma, pressurized fluids, pulsed electric fields, ohmic heating, radiofrequency electric fields, ultrasonics and megasonics, high hydrostatic pressure, high pressure homogenization, hyperbaric storage, and negative pressure cavitation extraction) have attracted much attention in the past decades. This is because, compared to their conventional counterparts, novel food processes allow a significant reduction in the overall processing times with savings in energy consumption, while ensuring food safety, and ample benefits for the industry. Noteworthily, industry and university teams have made extensive efforts for the development of novel technologies, with sound scientific knowledge of their effects on different food materials. The main objective of this review is to provide a historical account of the extensive efforts and inventions in the field of emerging food processing technologies since their inception to present day. Copyright © 2017 Elsevier Ltd. All rights reserved.

Ethics in biotechnology and biosecurity.

PubMed

Jameel, S

2011-01-01

Great advances in technology produce unique challenges. Every technology also has a dual use, which needs to be understood and managed to extract maximum benefits for mankind and the development of civilization. The achievements of physicists in the mid-20th century resulted in the nuclear technology, which gave us the destructive power of the atomic bomb as also a source of energy. Towards the later part of the 20th century, information technology empowered us with fast, easy and cheap access to information, but also led to intrusions into our privacy. Today, biotechnology is yielding life- saving and life-enhancing advances at a fast pace. But, the same tools can also give rise to fiercely destructive forces. How do we construct a security regime for biology? What have we learnt from the management of earlier technological advances? How much information should be in the public domain? Should biology, or more broadly science, be regulated? Who should regulate it? These and many other ethical questions need to be addressed.

Raising quality of maintenance and control of metallic structures in large-load technological machines

NASA Astrophysics Data System (ADS)

Drygin, M. Yu; Kuryshkin, N. P.

2018-01-01

Active growth of coal extraction and underinvestment of coal mining in Russia lead to the fact that technical state of more than 86% of technological machines at opencast coal mines is unacceptable. One of the most significant problems is unacceptable state of supporting metallic structures of excavators and mine dump trucks. The analysis has shown that defects in these metallic structures had been accumulated for a long time. Their removal by the existing method of repair welding was not effective - the flaws reappeared in 2-6 months of technological machines’ service. The authors detected the prime causes that did not allow to make a good repair welding joint. A new technology of repair welding had been tested and endorsed, and this allowed to reduce the number of welded joints’ flaws by 85% without additional raising welders’ qualification. As a result the number of flaws in metallic structures of the equipment had been reduced by 35 % as early as in the first year of using the new technology.

A three-dimensional laser vibration measurement technology realized on five laser beam and its calibration

NASA Astrophysics Data System (ADS)

Li, Lu-Ke; Zhang, Shen-Feng

2018-03-01

Put forward a kind of three-dimensional vibration information technology of vibrating object by the mean of five laser beam of He-Ne laser, and with the help of three-way sensor, measure the three-dimensional laser vibration developed by above mentioned technology. The technology based on the Doppler principle of interference and signal demodulation technology, get the vibration information of the object, through the algorithm processing, extract the three-dimensional vibration information of space objects, and can achieve the function of angle calibration of five beam in the space, which avoid the effects of the mechanical installation error, greatly improve the accuracy of measurement. With the help of a & B K4527 contact three axis sensor, measure and calibrate three-dimensional laser vibrometer, which ensure the accuracy of the measurement data. Summarize the advantages and disadvantages of contact and non-contact sensor, and analysis the future development trends of the sensor industry.

Supercritical fluid technology: a promising approach in pharmaceutical research.

PubMed

Girotra, Priti; Singh, Shailendra Kumar; Nagpal, Kalpana

2013-02-01

Supercritical fluids possess the unique properties of behaving like liquids and gases, above their critical point. Supercritical fluid technology has recently emerged as a green and novel technique for various processes such as solubility enhancement of poorly soluble drugs, plasticization of polymers, surface modification, nanosizing and nanocrystal modification, and chromatographic extraction. Research interest in this area has been fuelled because of the numerous advantages that the technology offers over the conventional methods. This work aims to review the merits, demerits, and various processes such as rapid expansion of supercritical solutions (RESS), particles from gas saturated solutions (PGSS), gas antisolvent process (GAS), supercritical antisolvent process (SAS) and polymerization induced phase separation (PIPS), that have enabled this technology to considerably raise the interest of researchers over the past two decades. An insight has been given into the numerous applications of this technology in pharmaceutical industry and the future challenges which must be appropriately dealt with to make it effective on a commercial scale.

End-User Evaluations of Semantic Web Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCool, Rob; Cowell, Andrew J.; Thurman, David A.

Stanford University's Knowledge Systems Laboratory (KSL) is working in partnership with Battelle Memorial Institute and IBM Watson Research Center to develop a suite of technologies for information extraction, knowledge representation & reasoning, and human-information interaction, in unison entitled 'Knowledge Associates for Novel Intelligence' (KANI). We have developed an integrated analytic environment composed of a collection of analyst associates, software components that aid the user at different stages of the information analysis process. An important part of our participatory design process has been to ensure our technologies and designs are tightly integrate with the needs and requirements of our end users,more » To this end, we perform a sequence of evaluations towards the end of the development process that ensure the technologies are both functional and usable. This paper reports on that process.« less

Technical and technological solution for vegetal bio-stimulants obtaining

NASA Astrophysics Data System (ADS)

Anghelache, D. G.; Diaconescu, I.; Pătraşcu, R.

2017-08-01

The paper presents a modern technology for bio fertilizers resulted from waste plant mass after harvesting crops Experimental products were obtained rich in nutrients, but unstable in terms of existing microorganisms. Therefore, they conducted further studies to obtaining bio fungicide herb, so in all investigations undertaken so far in the laboratory, were able to conclude that the introduction of medicinal plant extracts with fungicidal effect into the bio fertilizers obtained by degradation of plant material post-harvest can get various bio-stimulants with nourishing effect upon the plants. Following this technology the paper’s objective is to identify a flux scheme for experimental equipment which can produce as final outcome this type of bio-stimulant. Also, in this work, this equipment will be chosen and will be designed following and obeying to the request of every step of the above technology.

Nuclear Weapons. National Nuclear Security Administration’s Plans for Its Uranium Processing Facility Should Better Reflect Funding Estimates and Technology Readiness

DTIC Science & Technology

2010-11-01

metal. Recovery extraction centrifugal contactors A process that uses solvent to extract uranium for purposes of purification. Agile machining A...extraction centrifugal contactors 5 6 Yes 6 No Agile machining 5 5 No 6 No Chip management 5 6 Yes 6 No Special casting 3 6 Yes 6 No Source: GAO

An improved protocol for the preparation of total genomic DNA from isolates of yeast and mould using Whatman FTA filter papers.

PubMed

Borman, Andrew M; Fraser, Mark; Linton, Christopher J; Palmer, Michael D; Johnson, Elizabeth M

2010-06-01

Here, we present a significantly improved version of our previously published method for the extraction of fungal genomic DNA from pure cultures using Whatman FTA filter paper matrix technology. This modified protocol is extremely rapid, significantly more cost effective than our original method, and importantly, substantially reduces the problem of potential cross-contamination between sequential filters when employing FTA technology.

The design and implementation of image query system based on color feature

NASA Astrophysics Data System (ADS)

Yao, Xu-Dong; Jia, Da-Chun; Li, Lin

2013-07-01

ASP.NET technology was used to construct the B/S mode image query system. The theory and technology of database design, color feature extraction from image, index and retrieval in the construction of the image repository were researched. The campus LAN and WAN environment were used to test the system. From the test results, the needs of user queries about related resources were achieved by system architecture design.

2008 Joint Chemical Biological, Radiological and Nuclear (CBRN) Conference and Exhibition

DTIC Science & Technology

2008-06-26

Untitled Document 2008cbrn.html[5/16/ 2016 10:15:46 AM] 2008 Joint Chemical Biological, Radiological and Nuclear (CBRN) Conference & Exhibition... 2016 10:15:46 AM] Mr. Fred Crowson, Chief, Physical Science and Technology Division, Joint Science & Technology Office for Chemical and Biological... analysis Detect and measure alpha, beta, gamma, neutron, and x-ray emissions Levels A, B, and C capable Level A Level B 2-Jul-08 10 Extract Capabilities

Automated Cooperative Trajectories

NASA Technical Reports Server (NTRS)

Hanson, Curt; Pahle, Joseph; Brown, Nelson

2015-01-01

This presentation is an overview of the Automated Cooperative Trajectories project. An introduction to the phenomena of wake vortices is given, along with a summary of past research into the possibility of extracting energy from the wake by flying close parallel trajectories. Challenges and barriers to adoption of civilian automatic wake surfing technology are identified. A hardware-in-the-loop simulation is described that will support future research. Finally, a roadmap for future research and technology transition is proposed.

Orbital transfer vehicle launch operations study: Automated technology knowledge base, volume 4

NASA Technical Reports Server (NTRS)

1986-01-01

A simplified retrieval strategy for compiling automation-related bibliographies from NASA/RECON is presented. Two subsets of NASA Thesaurus subject terms were extracted: a primary list, which is used to obtain an initial set of citations; and a secondary list, which is used to limit or further specify a large initial set of citations. These subject term lists are presented in Appendix A as the Automated Technology Knowledge Base (ATKB) Thesaurus.

Evaluation of a minimally invasive system for measuring glucose area under the curve during oral glucose tolerance tests: usefulness of sweat monitoring for precise measurement.

PubMed

Sakaguchi, Kazuhiko; Hirota, Yushi; Hashimoto, Naoko; Ogawa, Wataru; Hamaguchi, Tomoya; Matsuo, Toshihiro; Miyagawa, Jun-ichiro; Namba, Mitsuyoshi; Sato, Toshiyuki; Okada, Seiki; Tomita, Koji; Matsuhisa, Munehide; Kaneto, Hideaki; Kosugi, Keisuke; Maegawa, Hiroshi; Nakajima, Hiromu; Kashiwagi, Atsunori

2013-05-01

We developed a system for measuring glucose area under the curve (AUC) using minimally invasive interstitial fluid extraction technology (MIET). Sweat contamination during interstitial fluid glucose (IG) extraction affects the accuracy of glucose AUC measurement, because this technology uses extracted sodium ion levels as an internal standard. Therefore, we developed a sweat monitoring patch to reduce this effect and investigated its efficacy in volunteers undergoing oral glucose tolerance tests (OGTTs). Fifty diabetes mellitus inpatients and 10 healthy subjects undergoing the 75 g OGTT were included. Two sites on the forearm were pretreated with microneedle arrays, then hydrogels for interstitial fluid extraction were placed on the treated sites. Simultaneously, hydrogels for sweat monitoring were placed on untreated sites near the treated sites. Plasma glucose (PG) levels were measured every 30 min for 2 h to calculate reference AUC values. Using MIET, IG AUC was calculated from extracted glucose and sodium ion levels after attachment of the hydrogel for 2 h. Good correlation between IG AUC measurements using MIET and reference AUCs measured using PG levels was confirmed over a wide AUC range (202-610 mg/h/dl) after correction for the sweat-induced error detected by the hydrogel patches on the nonpretreated skin. Strong correlation between IG AUC and peak glucose levels indicates that glucose spikes can be easily detected by this system. We confirmed the effectiveness of a sweat monitoring patch for precise AUC measurement using MIET. This novel, easy-to-use system has potential for glucose excursion evaluation in daily clinical practice. © 2013 Diabetes Technology Society.

Design and experimental investigation of an oxy-fuel combustion system for magnetohydrodynamic power extraction

NASA Astrophysics Data System (ADS)

Hernandez, Manuel Johannes

A general consensus in the scientific and research community is the need to restrict carbon emissions in energy systems. Therefore, extensive research efforts are underway to develop the next generation of energy systems. In the field of power generation, researchers are actively investigating novel methods to produce electricity in a cleaner, efficient form. Recently, Oxy-Combustion for magnetohydrodynamic power extraction has generated significant interest, since the idea was proposed as a method for clean power generation in coal and natural gas power plants. Oxy-combustion technologies have been proposed to provide high enthalpy, electrically conductive flows for direct conversion of electricity. Direct power extraction via magnetohydrodynamics (MHD) can occur as a consequence of the motion of "seeded" combustion products in the presence of magnetic fields. However, oxy-combustion technologies for MHD power extraction has not been demonstrated in the available literature. Furthermore, there are still fundamental unexplored questions remaining, associated with this technology, for MHD power extraction. In this present study, previous magnetohydrodynamic combustion technologies and technical issues in this field were assessed to develop a new combustion system for electrically conductive flows. The research aims were to fully understand the current-state-of-the-art of open-cycle magnetohydrodynamic technologies and present new future directions and concepts. The design criteria, methodology, and technical specifications of an advanced cooled oxy-combustion technology are presented in this dissertation. The design was based on a combined analytical, empirical, and numerical approach. Analytical one-dimensional (1D) design tools initiated design construction. Design variants were analyzed and vetted against performance criteria through the application of computational fluid dynamics modeling. CFD-generated flow fields permitted insightful visualization of the design concepts. Therefore, numerical computational fluid dynamics (CFD) models were developed to design and optimize the combustion flow fields of oxy-fuel combustion systems. These models were analyzed to understand the boundary layer and heat transfer profile and qualitative behaviors in the product designs. Advanced materials for high-temperature applications were assessed for their possible implementation in the product design. A trade-off analysis indicated that this scheme may incur elevated product cost and a difficulty in manufacturing. Active cooling strategies were considered for product development. A rocket-based cooling scheme, regenerative cooling, was implemented to provide active cooling. In the hot gas path (HGP) cooling design, CFD models were developed to predict the variation of heat removal along the oxy-combustion wall for various operating conditions. The oxy-combustion technology was manufactured using electrical discharge machining (EDM). The product development lifecycle in this dissertation encompassed preliminary design, detailed design, and demonstration and validation of the product. Towards the final stages of the product development, Fuel-rich oxy combustion experiments were carried out to demonstrate and observe flame characteristics from the designed technology and to predict heat transfer loads. The demonstration findings of oxy-combustion flames are presented in this work to contribute the developing field of MHD direct power extraction, which lacks oxy-combustion design data and qualitative combustion datasets. The findings show that this oxy-combustion concept is capable of providing a high-enthalpy MHD environment for seeding, in order to render the flow to be conductive. Based on previous findings, temperatures in the range of 2800-3000 K may enable magnetohydrodynamic power extraction. The combustor hardware design was developed to contribute to engineered systems rated less than 100 kW for demonstration. The product hardware was designed to produce gas velocities of 2000 m/s gas and temperatures within the following range of 2800-3000 K. In the injection system, the momentum flux ratio (MFR) was estimated to be 16. The heat loss fraction in this oxy-combustion system, based on CFD and analytical calculations, at optimal operating conditions, was estimated to be less than 10 percent. Furthermore, the heat transfer design removed approximately 7 MW/m2. The experimental performance of oxy-combustion systems demonstrates promise for advanced power generation applications.

The CHPM2030 H2020 Project: Combined Heat, Power and Metal extraction from ultra-deep ore bodies

NASA Astrophysics Data System (ADS)

Miklovicz, Tamas; Bodo, Balazs; Cseko, Adrienn; Hartai, Eva; Madarasz, Tamas

2017-04-01

The CHPM2030 project consortium is working on a novel technology solution that can provide both geothermal energy and minerals, in a single interlinked process. The CHPM technology involves an integrated approach to cross fertilize between two yet separated research areas: unconventional geothermal energy and mineral extraction. This places the project's research agenda onto the frontiers of geothermal resources development, mineral extraction and electro-metallurgy with the objectives of converting ultra-deep metallic mineral formations into an "orebody-enhanced geothermal system". In the envisioned facility, an EGS is established on a 3-4 km deep ore mineralisation. Metal content from the ore body is mobilised using mild leaching and/or nanoparticles, then metals are recovered by high-temperature, high-pressure geothermal fluid electrolysis and gas-diffusion electroprecipitation and electrocrystallisation. Salinity gradient power from pre-treated geothermal fluids will also be used. In the project, all these will be carried out at laboratory scale (technology readiness level of 4-5), providing data for the conceptual framework, process optimisation and simulations. Integrated sustainability assessment will also be carried out on the economic feasibility, social impact, policy considerations, environmental impact and ethics concerns. During the last stage of the research agenda, the work will focus on mapping converging technological areas, setting a background for pilot implementation and developing research roadmaps for 2030 and 2050. Pilot study areas include South West England, the Iberian Pyrite Belt in Portugal, the Banatitic Magmatic and Metallogenic Belt in Romania, and three mining districts in Sweden. The project started in January 2016 and lasts for 42 months. In the first phase, the metallogenesis of Europe was investigated and the potential ore formations have been identified. The rock-mechanical characteristics of orebodies have also been examined from an EGS perspective and the conceptual framework for an orebody-EGS has been formulated. Metal extraction from geothermal resources provides added value to the system, which has the potential to increase financial feasibility of geothermal development. This approach can contribute to a Europe-wide growth in industrial applications of geothermal resources in the future. The project also thrives to connect thousands of scientists, engineers, and decision-makers by establishing co-operative links to already running on critical raw materials, geothermal energy and other technology-driven projects.

Fruit wastes fermentation for phenolic antioxidants production and their application in manufacture of edible coatings and films.

PubMed

Martinez-Avila, G C G; Aguilera, A F; Saucedo, S; Rojas, R; Rodriguez, R; Aguilar, C N

2014-01-01

Agro-industrial by-products are important sources of potent bioactive phenolic compounds. These compounds are of extreme relevance for food and pharmacological industries due to their great variety of biological activities. Fermentation represents an environmentally clean technology for production and extraction of these bioactive compounds, providing high quality and high activity extracts, which can be incorporated in foods using coatings/films wax-based in order to avoid alterations in their quality. In this document is presented an overview about importance and benefits of solid-state fermentation, pointing out this bioprocess as an alternative technology for use agro-industrial by-products as substrates to produce valuable secondary metabolites and their applications as food quality conservatives.

Carotenoids from microalgae: A review of recent developments.

PubMed

Gong, Mengyue; Bassi, Amarjeet

2016-12-01

Carotenoids have been receiving increasing attention due to their potential health benefits. Microalgae are recognized as a natural source of carotenoids and other beneficial byproducts. However, the production of micro-algal carotenoids is not yet sufficiently cost-effective to compete with traditional chemical synthetic methods and other technologies such as extraction from plant based sources. This review presents the recent biotechnological developments in microalgal carotenoid production. The current technologies involved in their bioprocessing including cultivation, harvesting, extraction, and purification are discussed with a specific focus on downstream processing. The recent advances in chemical and biochemical synthesis of carotenoids are also reviewed for a better understanding of suitable and economically feasible biotechnological strategies. Some possible future directions are also proposed. Copyright © 2016 Elsevier Inc. All rights reserved.

1985 Particle Accelerator Conference: Accelerator Engineering and Technology, 11th, Vancouver, Canada, May 13-16, 1985, Proceedings

NASA Astrophysics Data System (ADS)

Strathdee, A.

1985-10-01

The topics discussed are related to high-energy accelerators and colliders, particle sources and electrostatic accelerators, controls, instrumentation and feedback, beam dynamics, low- and intermediate-energy circular accelerators and rings, RF and other acceleration systems, beam injection, extraction and transport, operations and safety, linear accelerators, applications of accelerators, radiation sources, superconducting supercolliders, new acceleration techniques, superconducting components, cryogenics, and vacuum. Accelerator and storage ring control systems are considered along with linear and nonlinear orbit theory, transverse and longitudinal instabilities and cures, beam cooling, injection and extraction orbit theory, high current dynamics, general beam dynamics, and medical and radioisotope applications. Attention is given to superconducting RF structures, magnet technology, superconducting magnets, and physics opportunities with relativistic heavy ion accelerators.

High-Efficiency Nitride-Base Photonic Crystal Light Sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

James Speck; Evelyn Hu; Claude Weisbuch

2010-01-31

The research activities performed in the framework of this project represent a major breakthrough in the demonstration of Photonic Crystals (PhC) as a competitive technology for LEDs with high light extraction efficiency. The goals of the project were to explore the viable approaches to manufacturability of PhC LEDS through proven standard industrial processes, establish the limits of light extraction by various concepts of PhC LEDs, and determine the possible advantages of PhC LEDs over current and forthcoming LED extraction concepts. We have developed three very different geometries for PhC light extraction in LEDs. In addition, we have demonstrated reliable methodsmore » for their in-depth analysis allowing the extraction of important parameters such as light extraction efficiency, modal extraction length, directionality, internal and external quantum efficiency. The information gained allows better understanding of the physical processes and the effect of the design parameters on the light directionality and extraction efficiency. As a result, we produced LEDs with controllable emission directionality and a state of the art extraction efficiency that goes up to 94%. Those devices are based on embedded air-gap PhC - a novel technology concept developed in the framework of this project. They rely on a simple and planar fabrication process that is very interesting for industrial implementation due to its robustness and scalability. In fact, besides the additional patterning and regrowth steps, the process is identical as that for standard industrially used p-side-up LEDs. The final devices exhibit the same good electrical characteristics and high process yield as a series of test standard LEDs obtained in comparable conditions. Finally, the technology of embedded air-gap patterns (PhC) has significant potential in other related fields such as: increasing the optical mode interaction with the active region in semiconductor lasers; increasing the coupling of the incident light into the active region of solar cells; increasing the efficiency of the phosphorous light conversion in white light LEDs etc. In addition to the technology of embedded PhC LEDs, we demonstrate a technique for improvement of the light extraction and emission directionality for existing flip-chip microcavity (thin) LEDs by introducing PhC grating into the top n-contact. Although, the performances of these devices in terms of increase of the extraction efficiency are not significantly superior compared to those obtained by other techniques like surface roughening, the use of PhC offers some significant advantages such as improved and controllable emission directionality and a process that is directly applicable to any material system. The PhC microcavity LEDs have also potential for industrial implementation as the fabrication process has only minor differences to that already used for flip-chip thin LEDs. Finally, we have demonstrated that achieving good electrical properties and high fabrication yield for these devices is straightforward.« less

Technological Innovations for High-Throughput Approaches to In Vitro Allergy Diagnosis.

PubMed

Chapman, Martin D; Wuenschmann, Sabina; King, Eva; Pomés, Anna

2015-07-01

Allergy diagnostics is being transformed by the advent of in vitro IgE testing using purified allergen molecules, combined with multiplex technology and biosensors, to deliver discriminating, sensitive, and high-throughput molecular diagnostics at the point of care. Essential elements of IgE molecular diagnostics are purified natural or recombinant allergens with defined purity and IgE reactivity, planar or bead-based multiplex systems to enable IgE to multiple allergens to be measured simultaneously, and, most recently, nanotechnology-based biosensors that facilitate rapid reaction rates and delivery of test results via mobile devices. Molecular diagnostics relies on measurement of IgE to purified allergens, the "active ingredients" of allergenic extracts. Typically, this involves measuring IgE to multiple allergens which is facilitated by multiplex technology and biosensors. The technology differentiates between clinically significant cross-reactive allergens (which could not be deduced by conventional IgE assays using allergenic extracts) and provides better diagnostic outcomes. Purified allergens are manufactured under good laboratory practice and validated using protein chemistry, mass spectrometry, and IgE antibody binding. Recently, multiple allergens (from dog) were expressed as a single molecule with high diagnostic efficacy. Challenges faced by molecular allergy diagnostic companies include generation of large panels of purified allergens with known diagnostic efficacy, access to flexible and robust array or sensor technology, and, importantly, access to well-defined serum panels form allergic patients for product development and validation. Innovations in IgE molecular diagnostics are rapidly being brought to market and will strengthen allergy testing at the point of care.

Custom-made, root-analogue direct laser metal forming implant: a case report.

PubMed

Mangano, Francesco Guido; Cirotti, Bruno; Sammons, Rachel Lilian; Mangano, Carlo

2012-11-01

In the last few years, the application of digital technology in dentistry has become widespread with the introduction of cone beam computed tomography (CBCT) scan technology, and considerable progress has been made in the development of computer-aided design/ computer-aided manufacturing (CAD/CAM) techniques, including direct laser metal forming (DLMF). DLMF is a technology which allows solids with complex geometry to be produced by annealing metal powder microparticles in a focused laser beam, according to a computer-generated three-dimensional (3D) model. For dental implants, the fabrication process involves the laser-induced fusion of titanium microparticles, in order to build, layer by layer, the desired object. At present, the combined use of CBCT 3D data and CAD/CAM technology makes it possible to manufacture custom-made, root-analogue implants (RAI) with sufficient precision. This report demonstrates the successful clinical use of a custom-made, root-analogue DLMF implant. CBCT images of a non-restorable right maxillary first premolar were acquired and transformed into a 3D model. From this model, a custom-made, root-analogue DLMF implant was fabricated. Immediately after tooth extraction, the RAI with a pre-operatively designed abutment was placed in the extraction socket and restored with a single crown. At the 1-year follow-up examination, the RAI showed a good functional and aesthetic integration. The introduction of DLMF technology signals the start of a new revolutionary era for implant dentistry as its immense potential for producing highly complex macro- and microstructures is receiving vast interest in different medical fields.

Site remediation using photocatalytic VOC destruction of chlorinated hydrocarbons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brunet, R.A.H.; Pearcey, R.; Kittrell, J.R.

1999-07-01

An innovative environmental technology has been developed and demonstrated for cost-effective control of toxic air emissions, such as trichloroethylene (TCE) and perchloroethylene (PCE), found in soil and groundwater at hazardous waste sites and in industrial effluents. The technology uses UV light and a proprietary photocatalyst to adsorb and destroy pollutants at ambient conditions, even with high humidity. Air stripping and soil vapor extraction efficiently transfer the pollutants to the gas phase, where they can be economically treated by photocatalysis without the risk of hazardous by-product formation. The AIR2000 photocatalytic technology was successfully installed at the Stamina Mills Superfund site inmore » Rhode Island, where a commercial scale unit is treating 700 cfm of up to 1,000 ppm TCE, mixed with PCE, dichloroethylene (DCE), trichloroethane (TCA), and vinyl chloride (VC) produced through a combination of soil vapor extraction (SVE) and air stripping. As part of the EPA SITE program, the system was monitored for overall destruction removal efficiency (DRE) and hazardous by-product formation. A DRE in excess of 99% was reported over the first four months of operation, with greater than 99.99% DRE achieved, without production of hazardous by-products. The operating cost of the system is approximately 20% of activated carbon adsorption, which provides approximately $1,500,000 in cost savings over the life of the Stamina Mills project. The Adsorption Integrated Reaction (AIR) process is the recipient of the 1997 SBIR Technology of the Year award, the 1998 EPA Environmental Technology Innovator Award, and the 1998 R and D 100 Award.« less

EASY-HIT: HIV full-replication technology for broad discovery of multiple classes of HIV inhibitors.

PubMed

Kremb, Stephan; Helfer, Markus; Heller, Werner; Hoffmann, Dieter; Wolff, Horst; Kleinschmidt, Andrea; Cepok, Sabine; Hemmer, Bernhard; Durner, Jörg; Brack-Werner, Ruth

2010-12-01

HIV replication assays are important tools for HIV drug discovery efforts. Here, we present a full HIV replication system (EASY-HIT) for the identification and analysis of HIV inhibitors. This technology is based on adherently growing HIV-susceptible cells, with a stable fluorescent reporter gene activated by HIV Tat and Rev. A fluorescence-based assay was designed that measures HIV infection by two parameters relating to the early and the late phases of HIV replication, respectively. Validation of the assay with a panel of nine reference inhibitors yielded effective inhibitory concentrations consistent with published data and allowed discrimination between inhibitors of early and late phases of HIV replication. Finer resolution of the effects of reference drugs on different steps of HIV replication was achieved in secondary time-of-addition assays. The EASY-HIT assay yielded high Z' scores (>0.9) and signal stabilities, confirming its robustness. Screening of the LOPAC(1280) library identified 10 compounds (0.8%), of which eight were known to inhibit HIV, validating the suitability of this assay for screening applications. Studies evaluating anti-HIV activities of natural products with the EASY-HIT technology led to the identification of three novel inhibitory compounds that apparently act at different steps of HIV-1 replication. Furthermore, we demonstrate successful evaluation of plant extracts for HIV-inhibitory activities, suggesting application of this technology for the surveillance of biological extracts with anti-HIV activities. We conclude that the EASY-HIT technology is a versatile tool for the discovery and characterization of HIV inhibitors.

Public funding of pharmaceuticals in The Netherlands: investigating the effect of evidence, process and context on CVZ decision-making.

PubMed

Cerri, Karin H; Knapp, Martin; Fernandez, Jose-Luis

2014-09-01

The College Voor Zorgverzekeringen (CVZ) provides guidance to the Dutch healthcare system on funding and use of new pharmaceutical technologies. This study examined the impact of evidence, process and context factors on CVZ decisions in 2004-2009. A data set of CVZ decisions pertaining to pharmaceutical technologies was created, including 29 variables extracted from published information. A three-category outcome variable was used, defined as the decision to 'recommend', 'restrict' or 'not recommend' a technology. Technologies included in list 1A/1B or on the expensive drug list were considered recommended; those included in list 2 or for which patient co-payment is required were considered restricted; technologies not included on any reimbursement list were classified as 'not recommended'. Using multinomial logistic regression, the relative contribution of explanatory variables on CVZ decisions was assessed. In all, 244 technology appraisals (256 technologies) were analysed, with 51%, of technologies recommended, 33% restricted and 16% not recommended by CVZ for funding. The multinomial model showed significant associations (p ≤ 0.10) between CVZ outcome and several variables, including: (1) use of an active comparator and demonstration of statistical superiority of the primary endpoint in clinical trials, (2) pharmaceutical budget impact associated with introduction of the technology, (3) therapeutic indication and (4) prevalence of the target population. Results confirm the value of a comprehensive and multivariate approach to understanding CVZ decision-making.

NASA's Advanced Information Systems Technology (AIST) Program: Advanced Concepts and Disruptive Technologies

NASA Astrophysics Data System (ADS)

Little, M. M.; Moe, K.; Komar, G.

2014-12-01

NASA's Earth Science Technology Office (ESTO) manages a wide range of information technology projects under the Advanced Information Systems Technology (AIST) Program. The AIST Program aims to support all phases of NASA's Earth Science program with the goal of enabling new observations and information products, increasing the accessibility and use of Earth observations, and reducing the risk and cost of satellite and ground based information systems. Recent initiatives feature computational technologies to improve information extracted from data streams or model outputs and researchers' tools for Big Data analytics. Data-centric technologies enable research communities to facilitate collaboration and increase the speed with which results are produced and published. In the future NASA anticipates more small satellites (e.g., CubeSats), mobile drones and ground-based in-situ sensors will advance the state-of-the-art regarding how scientific observations are performed, given the flexibility, cost and deployment advantages of new operations technologies. This paper reviews the success of the program and the lessons learned. Infusion of these technologies is challenging and the paper discusses the obstacles and strategies to adoption by the earth science research and application efforts. It also describes alternative perspectives for the future program direction and for realizing the value in the steps to transform observations from sensors to data, to information, and to knowledge, namely: sensor measurement concepts development; data acquisition and management; data product generation; and data exploitation for science and applications.

Technology whitespaces India should focus: a comparative anti-cancer patent rational analysis of Indian and international public funded universities.

PubMed

Dara, Ajay; Sangamwar, Abhay T

2015-01-01

The article reported an in-depth comparative technology analysis of 1708 Anti-cancer patents from top 20 international universities and leading 10 Indian public funded organization and research institutes. The study segregated pioneer universities vs. technologies used in the field of Anticancer research at a level of drug discovery, development, diagnosis and treatment, which are illustrated in the form of novel substantive patent landscape maps. The reported competitive intelligent maps identified genetics, composition and synthetic compounds as dominating technologies; followed by natural extracts, combination and drug delivery systems as upcoming technologies. The least number of patents were reported by surgical apparatus, targeted therapy and animal models. In addition, the study analysed the key technologies followed by Indian universities in comparison to the international universities, to identify the overlooked technologies by the Indian public funded institutes. In an ever changing competitive world, it is essential for every university to have their own research plan and thrust areas; but at the same time, it is equally important for any organisation to have an idea of their competitor's research plan as well. So, the article suggested Indian institutes to focus on the latest emerging Anti-cancer technology trends, which are in practice by the international universities. Concurrently, this study may be a landmark indication for Indian public funded universities and institutes, calling for a U-turn from their traditional approaches.

Final Technical Report Recovery Act: Online Nonintrusive Condition Monitoring and Fault Detection for Wind Turbines

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wei Qiao

2012-05-29

The penetration of wind power has increased greatly over the last decade in the United States and across the world. The U.S. wind power industry installed 1,118 MW of new capacity in the first quarter of 2011 alone and entered the second quarter with another 5,600 MW under construction. By 2030, wind energy is expected to provide 20% of the U.S. electricity needs. As the number of wind turbines continues to grow, the need for effective condition monitoring and fault detection (CMFD) systems becomes increasingly important [3]. Online CMFD is an effective means of not only improving the reliability, capacitymore » factor, and lifetime, but it also reduces the downtime, energy loss, and operation and maintenance (O&M) of wind turbines. The goal of this project is to develop novel online nonintrusive CMFD technologies for wind turbines. The proposed technologies use only the current measurements that have been used by the control and protection system of a wind turbine generator (WTG); no additional sensors or data acquisition devices are needed. Current signals are reliable and easily accessible from the ground without intruding on the wind turbine generators (WTGs) that are situated on high towers and installed in remote areas. Therefore, current-based CMFD techniques have great economic benefits and the potential to be adopted by the wind energy industry. Specifically, the following objectives and results have been achieved in this project: (1) Analyzed the effects of faults in a WTG on the generator currents of the WTG operating at variable rotating speed conditions from the perspective of amplitude and frequency modulations of the current measurements; (2) Developed effective amplitude and frequency demodulation methods for appropriate signal conditioning of the current measurements to improve the accuracy and reliability of wind turbine CMFD; (3) Developed a 1P-invariant power spectrum density (PSD) method for effective signature extraction of wind turbine faults with characteristic frequencies in the current or current demodulated signals, where 1P stands for the shaft rotating frequency of a WTG; (4) Developed a wavelet filter for effective signature extraction of wind turbine faults without characteristic frequencies in the current or current demodulated signals; (5) Developed an effective adaptive noise cancellation method as an alternative to the wavelet filter method for signature extraction of wind turbine faults without characteristic frequencies in the current or current demodulated signals; (6) Developed a statistical analysis-based impulse detection method for effective fault signature extraction and evaluation of WTGs based on the 1P-invariant PSD of the current or current demodulated signals; (7) Validated the proposed current-based wind turbine CMFD technologies through extensive computer simulations and experiments for small direct-drive WTGs without gearboxes; and (8) Showed, through extensive experiments for small direct-drive WTGs, that the performance of the proposed current-based wind turbine CMFD technologies is comparable to traditional vibration-based methods. The proposed technologies have been successfully applied for detection of major failures in blades, shafts, bearings, and generators of small direct-drive WTGs. The proposed technologies can be easily integrated into existing wind turbine control, protection, and monitoring systems and can be implemented remotely from the wind turbines being monitored. The proposed technologies provide an alternative to vibration-sensor-based CMFD. This will reduce the cost and hardware complexity of wind turbine CMFD systems. The proposed technologies can also be combined with vibration-sensor-based methods to improve the accuracy and reliability of wind turbine CMFD systems. When there are problems with sensors, the proposed technologies will ensure proper CMFD for the wind turbines, including their sensing systems. In conclusion, the proposed technologies offer an effective means to achieve condition-based smart maintenance for wind turbines and have a great potential to be adopted by the wind energy industry due to their almost no-cost, nonintrusive features. Although only validated for small direct-drive wind turbines without gearboxes, the proposed technologies are also applicable for CMFD of large-size wind turbines with and without gearboxes. However, additional investigations are recommended in order to apply the proposed technologies to those large-size wind turbines.« less

INTERIM REPORT ON THE EVOLUTION AND ...

EPA Pesticide Factsheets

A demonstration of screening technologies for determining the presence of dioxin and dioxin-like compounds in soil and sediment was conducted under the U.S. Environmental Protection Agency's(EPA's) Superfund Innovative Technology Evaluation Program in Saginaw, Michigan in 2004. The objectives of the demonstration included evaluating each participating technology's accuracy, precision, sensitivity, sample throughput, tendency for matrix effects, and cost. The test also included an assessment of how well the technology's results compared to those generated by established laboratory methods using high-resolution mass spectrometry (HRMS). The demonstration objectives were accomplished by evaluating the results generated by each technology from 209 soil, sediment, and extract samples. The test samples included performance evaluation (PE) samples (i.e., contaminant concentrations were certified or the samples were spiked with known contaminants) and environmental samples collected from 10 different sampling locations. The PE and environmental samples were distributed to the technology developers in blind, random order. One of the participants in the original SITE demonstration was Hybrizyme Corporation, which demonstrated the use of the AhRC PCR Kit. The AhRC PCR Kit was a technology that reported the concentration of aryl hydrocarbon receptor (AhR) binding compounds in a sample, with units reported as Ah Receptor Binding Units (AhRBU). At the time of the original dem

NanoString, a novel digital color-coded barcode technology: current and future applications in molecular diagnostics.

PubMed

Tsang, Hin-Fung; Xue, Vivian Weiwen; Koh, Su-Pin; Chiu, Ya-Ming; Ng, Lawrence Po-Wah; Wong, Sze-Chuen Cesar

2017-01-01

Formalin-fixed, paraffin-embedded (FFPE) tissue sample is a gold mine of resources for molecular diagnosis and retrospective clinical studies. Although molecular technologies have expanded the range of mutations identified in FFPE samples, the applications of existing technologies are limited by the low nucleic acids yield and poor extraction quality. As a result, the routine clinical applications of molecular diagnosis using FFPE samples has been associated with many practical challenges. NanoString technologies utilize a novel digital color-coded barcode technology based on direct multiplexed measurement of gene expression and offer high levels of precision and sensitivity. Each color-coded barcode is attached to a single target-specific probe corresponding to a single gene which can be individually counted without amplification. Therefore, NanoString is especially useful for measuring gene expression in degraded clinical specimens. Areas covered: This article describes the applications of NanoString technologies in molecular diagnostics and challenges associated with its applications and the future development. Expert commentary: Although NanoString technology is still in the early stages of clinical use, it is expected that NanoString-based cancer expression panels would play more important roles in the future in classifying cancer patients and in predicting the response to therapy for better personal therapeutic care.

Clearing the Fog of Anticancer Patents from 1993–2013: Through an In-Depth Technology Landscape & Target Analysis from Pioneer Research Institutes and Universities Worldwide

PubMed Central

Dara, Ajay; Sangamwar, Abhay T.

2014-01-01

Background In a search for an effective anticancer therapy the R&D units from leading universities and institutes reveal numerous technologies in the form of patent documents. The article addressed comparative anticancer patent landscape and technology assessment of Council of Scientific and Industrial Research (CSIR): India’s largest R&D organisation with top twenty international public funded universities and institutes from eight different countries. Methodology/Principal Findings The methodology include quantitative and qualitative assessment based on the bibliometric parameters and manual technology categorisation to understand the changing patent trends and recent novel technologies. The research finding analysed 25,254 patent documents from the year 1993 to 2013 and reported the insights of latest anticancer technologies and targets through categorisation studies at the level of drug discovery, development and treatment & diagnosis. The article has reported the technology correlation matrix of twelve secondary class technologies with 34 tertiary sub-class research area to identify the leading technologies and scope of future research through whitespaces analysis. In addition, the results have also addressed the target analysis, leading inventor, assignee, collaboration network, geographical distribution, patent trend analysis, citation maps and technology assessment with respect to international patent classification systems such as CPC, IPC and CPI codes. Conclusions/Significance The result suggested peptide technology as the dominating research area next to gene therapy, vaccine and medical preparation containing organic compounds. The Indian CSIR has ranked itself at seventh position among the top 20 universities. Globally, the anticancer research was focused in the area of genetics and immunology, whereas Indian CSIR reported more patents related to plant extract and organic preparation. The article provided a glimpse of two decade anticancer scenario with respect to top public funded universities worldwide. PMID:25083710

Clearing the fog of anticancer patents from 1993-2013: through an in-depth technology landscape & target analysis from pioneer research institutes and universities worldwide.

PubMed

Dara, Ajay; Sangamwar, Abhay T

2014-01-01

In a search for an effective anticancer therapy the R&D units from leading universities and institutes reveal numerous technologies in the form of patent documents. The article addressed comparative anticancer patent landscape and technology assessment of Council of Scientific and Industrial Research (CSIR): India's largest R&D organisation with top twenty international public funded universities and institutes from eight different countries. The methodology include quantitative and qualitative assessment based on the bibliometric parameters and manual technology categorisation to understand the changing patent trends and recent novel technologies. The research finding analysed 25,254 patent documents from the year 1993 to 2013 and reported the insights of latest anticancer technologies and targets through categorisation studies at the level of drug discovery, development and treatment & diagnosis. The article has reported the technology correlation matrix of twelve secondary class technologies with 34 tertiary sub-class research area to identify the leading technologies and scope of future research through whitespaces analysis. In addition, the results have also addressed the target analysis, leading inventor, assignee, collaboration network, geographical distribution, patent trend analysis, citation maps and technology assessment with respect to international patent classification systems such as CPC, IPC and CPI codes. The result suggested peptide technology as the dominating research area next to gene therapy, vaccine and medical preparation containing organic compounds. The Indian CSIR has ranked itself at seventh position among the top 20 universities. Globally, the anticancer research was focused in the area of genetics and immunology, whereas Indian CSIR reported more patents related to plant extract and organic preparation. The article provided a glimpse of two decade anticancer scenario with respect to top public funded universities worldwide.

Modelling assistive technology adoption for people with dementia.

PubMed

Chaurasia, Priyanka; McClean, Sally I; Nugent, Chris D; Cleland, Ian; Zhang, Shuai; Donnelly, Mark P; Scotney, Bryan W; Sanders, Chelsea; Smith, Ken; Norton, Maria C; Tschanz, JoAnn

2016-10-01

Assistive technologies have been identified as a potential solution for the provision of elderly care. Such technologies have in general the capacity to enhance the quality of life and increase the level of independence among their users. Nevertheless, the acceptance of these technologies is crucial to their success. Generally speaking, the elderly are not well-disposed to technologies and have limited experience; these factors contribute towards limiting the widespread acceptance of technology. It is therefore important to evaluate the potential success of technologies prior to their deployment. The research described in this paper builds upon our previous work on modelling adoption of assistive technology, in the form of cognitive prosthetics such as reminder apps and aims at identifying a refined sub-set of features which offer improved accuracy in predicting technology adoption. Consequently, in this paper, an adoption model is built using a set of features extracted from a user's background to minimise the likelihood of non-adoption. The work is based on analysis of data from the Cache County Study on Memory and Aging (CCSMA) with 31 features covering a range of age, gender, education and details of health condition. In the process of modelling adoption, feature selection and feature reduction is carried out followed by identifying the best classification models. With the reduced set of labelled features the technology adoption model built achieved an average prediction accuracy of 92.48% when tested on 173 participants. We conclude that modelling user adoption from a range of parameters such as physical, environmental and social perspectives is beneficial in recommending a technology to a particular user based on their profile. Copyright © 2016 Elsevier Inc. All rights reserved.

[Identification of green tea brand based on hyperspectra imaging technology].

PubMed

Zhang, Hai-Liang; Liu, Xiao-Li; Zhu, Feng-Le; He, Yong

2014-05-01

Hyperspectral imaging technology was developed to identify different brand famous green tea based on PCA information and image information fusion. First 512 spectral images of six brands of famous green tea in the 380 approximately 1 023 nm wavelength range were collected and principal component analysis (PCA) was performed with the goal of selecting two characteristic bands (545 and 611 nm) that could potentially be used for classification system. Then, 12 gray level co-occurrence matrix (GLCM) features (i. e., mean, covariance, homogeneity, energy, contrast, correlation, entropy, inverse gap, contrast, difference from the second-order and autocorrelation) based on the statistical moment were extracted from each characteristic band image. Finally, integration of the 12 texture features and three PCA spectral characteristics for each green tea sample were extracted as the input of LS-SVM. Experimental results showed that discriminating rate was 100% in the prediction set. The receiver operating characteristic curve (ROC) assessment methods were used to evaluate the LS-SVM classification algorithm. Overall results sufficiently demonstrate that hyperspectral imaging technology can be used to perform classification of green tea.

Gold nanorods based diffusion reflection measurements: current status and perspectives for clinical applications

NASA Astrophysics Data System (ADS)

Ankri, Rinat; Fixler, Dror

2017-07-01

Optical imaging is a powerful tool for investigating the structure and function of tissues. Tissue optical imaging technologies are generally discussed under two broad regimes: microscopic and macroscopic, while the latter is widely investigated in the field of light-tissue interaction. Among the developed optical technologies for tissue investigation, the diffusion reflectance (DR) method is a simple and safe technology. However, this method suffers from low specificity and low signal-to-noise ratio, so the extraction of the tissue properties is not an easy task. In this review, we describe the use of gold nanorods (GNRs) in DR spectroscopy. The GNRs present unique optical properties which enhance the scattering and absorption properties of a tissue. The GNRs can be easily targeted toward abnormal sites in order to improve the DR signal and to distinguish between the healthy and the abnormal sites in the tissue, with high specificity. This article describes the use of the DR-GNRs method for the detection of cancer and atherosclerosis, from light transfer theory, through the extraction of the tissue properties using the diffusion theory and up to DR in vivo measurements.

Sustainable Development Strategy for Russian Mineral Resources Extracting Economy

NASA Astrophysics Data System (ADS)

Dotsenko, Elena; Ezdina, Natalya; Prilepskaya, Angelina; Pivnyk, Kirill

2017-11-01

The immaturity of strategic and conceptual documents in the sphere of sustainable development of the Russian economy had a negative impact on long-term strategic forecasting of its neo-industrialization. At the present stage, the problems of overcoming the mineral and raw material dependence, the negative structural shift of the Russian economy, the acceleration of the rates of economic growth, the reduction of technological gap from the developed countries become strategically in demand. The modern structure of the Russian economy, developed within the framework of the proposed market model, does not generate a sustainable type of development. It became obvious that in conditions of the market processes' entropy, without neo-industrial changes, the reconstruction of industry on a new convergence-technological basis and without increasing the share of high technology production the instability of macroeconomic system, the risks of environmental and economic security of Russia are growing. Therefore, today we need a transition from forming one industry development strategy to the national one that will take into account both the social and economic and environmental challenges facing Russia as a mineral resources extracting country.

Promising Technologies of Mining and Processing of Solid Minerals

NASA Astrophysics Data System (ADS)

Shabaev, Sergey; Ivanov, Seregey; Vakhianov, Evgeniy

2017-11-01

The continuing growth in mineral extraction entails an increase in industrial waste, which in turn has a negative impact on the environment. Rubber-tired vehicles, in which the tires wear colossally, is mainly used as a transport for loading, unloading, transportation and other types of work in the extraction of solid minerals. The used tires are not disposed in any way, but are stored in special areas where harmful toxic substances are emitted under the influence of ultraviolet rays. Therefore, a decision was made to find a method for utilization and rational use of industrial waste in the road construction sector. The operating temperature of composite rubber-bituminous binders based on rubber crumb from the used automobile tires is estimated in this paper, which is necessary for assigning technological parameters of production and laying of asphalt-concrete mixtures produced on their basis. It is established that composite rubber-bituminous binders based on rubber chips from the used automobile tires, produced according to the two-stage technology, have the same viscosity as the original petroleum bitumen, at a temperature increased by 20°C.

Neo-Industrial and Sustainable Development of Russia as Mineral Resources Exploiting Country

NASA Astrophysics Data System (ADS)

Prokudina, Marina; Zhironkina, Olga; Kalinina, Oksana; Gasanov, Magerram; Agafonov, Felix

2017-11-01

In the Russian economy, the world leadership in the extraction of different mineral resources is combined with the potential for their processing and a significant scientific sector. Innovative development of raw materials extraction is impossible without the parallel technological modernization of the high-tech sector. In general, the complex of these processes is a neo-industrialization of the economy. Neo-industrially oriented transformation of the economy reflects complex changes in its structure, the transformation of established stable relationships between various elements of the system of social production that determine macroeconomic proportions. Neo-industrial transformations come along with the modification of economic relations associated with investments, innovations, labor and income distribution, with the process of locating productive forces and regulating the economy by the government. Neo-industrialization of economy is not only significant changes in its technological and reproductive structure (the development of high-tech industries, the integration of science and industry), but, above all, the implementation of a system structural policy of innovative development of raw material industry and the recovery of manufacturing industries on a new technological basis.

Data Processing and Text Mining Technologies on Electronic Medical Records: A Review

PubMed Central

Sun, Wencheng; Li, Yangyang; Liu, Fang; Fang, Shengqun; Wang, Guoyan

2018-01-01

Currently, medical institutes generally use EMR to record patient's condition, including diagnostic information, procedures performed, and treatment results. EMR has been recognized as a valuable resource for large-scale analysis. However, EMR has the characteristics of diversity, incompleteness, redundancy, and privacy, which make it difficult to carry out data mining and analysis directly. Therefore, it is necessary to preprocess the source data in order to improve data quality and improve the data mining results. Different types of data require different processing technologies. Most structured data commonly needs classic preprocessing technologies, including data cleansing, data integration, data transformation, and data reduction. For semistructured or unstructured data, such as medical text, containing more health information, it requires more complex and challenging processing methods. The task of information extraction for medical texts mainly includes NER (named-entity recognition) and RE (relation extraction). This paper focuses on the process of EMR processing and emphatically analyzes the key techniques. In addition, we make an in-depth study on the applications developed based on text mining together with the open challenges and research issues for future work. PMID:29849998

Sustainable Mars Sample Return

NASA Technical Reports Server (NTRS)

Alston, Christie; Hancock, Sean; Laub, Joshua; Perry, Christopher; Ash, Robert

2011-01-01

The proposed Mars sample return mission will be completed using natural Martian resources for the majority of its operations. The system uses the following technologies: In-Situ Propellant Production (ISPP), a methane-oxygen propelled Mars Ascent Vehicle (MAV), a carbon dioxide powered hopper, and a hydrogen fueled balloon system (large balloons and small weather balloons). The ISPP system will produce the hydrogen, methane, and oxygen using a Sabatier reactor. a water electrolysis cell, water extracted from the Martian surface, and carbon dioxide extracted from the Martian atmosphere. Indigenous hydrogen will fuel the balloon systems and locally-derived methane and oxygen will fuel the MAV for the return of a 50 kg sample to Earth. The ISPP system will have a production cycle of 800 days and the estimated overall mission length is 1355 days from Earth departure to return to low Earth orbit. Combining these advanced technologies will enable the proposed sample return mission to be executed with reduced initial launch mass and thus be more cost efficient. The successful completion of this mission will serve as the next step in the advancement of Mars exploration technology.

Profile and Functional Properties of Seed Proteins from Six Pea (Pisum sativum) Genotypes

PubMed Central

Barac, Miroljub; Cabrilo, Slavica; Pesic, Mirjana; Stanojevic, Sladjana; Zilic, Sladjana; Macej, Ognjen; Ristic, Nikola

2010-01-01

Extractability, extractable protein compositions, technological-functional properties of pea (Pisum sativum) proteins from six genotypes grown in Serbia were investigated. Also, the relationship between these characteristics was presented. Investigated genotypes showed significant differences in storage protein content, composition and extractability. The ratio of vicilin:legumin concentrations, as well as the ratio of vicilin + convicilin: Legumin concentrations were positively correlated with extractability. Our data suggest that the higher level of vicilin and/or a lower level of legumin have a positive influence on protein extractability. The emulsion activity index (EAI) was strongly and positively correlated with the solubility, while no significant correlation was found between emulsion stability (ESI) and solubility, nor between foaming properties and solubility. No association was evident between ESI and EAI. A moderate positive correlation between emulsion stability and foam capacity was observed. Proteins from the investigated genotypes expressed significantly different emulsifying properties and foam capacity at different pH values, whereas low foam stability was detected. It appears that genotype has considerable influence on content, composition and technological-functional properties of pea bean proteins. This fact can be very useful for food scientists in efforts to improve the quality of peas and pea protein products. PMID:21614186

Profile and functional properties of seed proteins from six pea (Pisum sativum) genotypes.

PubMed

Barac, Miroljub; Cabrilo, Slavica; Pesic, Mirjana; Stanojevic, Sladjana; Zilic, Sladjana; Macej, Ognjen; Ristic, Nikola

2010-01-01

Extractability, extractable protein compositions, technological-functional properties of pea (Pisum sativum) proteins from six genotypes grown in Serbia were investigated. Also, the relationship between these characteristics was presented. Investigated genotypes showed significant differences in storage protein content, composition and extractability. The ratio of vicilin:legumin concentrations, as well as the ratio of vicilin + convicilin: Legumin concentrations were positively correlated with extractability. Our data suggest that the higher level of vicilin and/or a lower level of legumin have a positive influence on protein extractability. The emulsion activity index (EAI) was strongly and positively correlated with the solubility, while no significant correlation was found between emulsion stability (ESI) and solubility, nor between foaming properties and solubility. No association was evident between ESI and EAI. A moderate positive correlation between emulsion stability and foam capacity was observed. Proteins from the investigated genotypes expressed significantly different emulsifying properties and foam capacity at different pH values, whereas low foam stability was detected. It appears that genotype has considerable influence on content, composition and technological-functional properties of pea bean proteins. This fact can be very useful for food scientists in efforts to improve the quality of peas and pea protein products.

Spectral Regression Based Fault Feature Extraction for Bearing Accelerometer Sensor Signals

PubMed Central

Xia, Zhanguo; Xia, Shixiong; Wan, Ling; Cai, Shiyu

2012-01-01

Bearings are not only the most important element but also a common source of failures in rotary machinery. Bearing fault prognosis technology has been receiving more and more attention recently, in particular because it plays an increasingly important role in avoiding the occurrence of accidents. Therein, fault feature extraction (FFE) of bearing accelerometer sensor signals is essential to highlight representative features of bearing conditions for machinery fault diagnosis and prognosis. This paper proposes a spectral regression (SR)-based approach for fault feature extraction from original features including time, frequency and time-frequency domain features of bearing accelerometer sensor signals. SR is a novel regression framework for efficient regularized subspace learning and feature extraction technology, and it uses the least squares method to obtain the best projection direction, rather than computing the density matrix of features, so it also has the advantage in dimensionality reduction. The effectiveness of the SR-based method is validated experimentally by applying the acquired vibration signals data to bearings. The experimental results indicate that SR can reduce the computation cost and preserve more structure information about different bearing faults and severities, and it is demonstrated that the proposed feature extraction scheme has an advantage over other similar approaches. PMID:23202017

A Review of Enzymatic Transesterification of Microalgal Oil-Based Biodiesel Using Supercritical Technology

PubMed Central

Taher, Hanifa; Al-Zuhair, Sulaiman; Al-Marzouqi, Ali H.; Haik, Yousef; Farid, Mohammed M.

2011-01-01

Biodiesel is considered a promising replacement to petroleum-derived diesel. Using oils extracted from agricultural crops competes with their use as food and cannot realistically satisfy the global demand of diesel-fuel requirements. On the other hand, microalgae, which have a much higher oil yield per hectare, compared to oil crops, appear to be a source that has the potential to completely replace fossil diesel. Microalgae oil extraction is a major step in the overall biodiesel production process. Recently, supercritical carbon dioxide (SC-CO2) has been proposed to replace conventional solvent extraction techniques because it is nontoxic, nonhazardous, chemically stable, and inexpensive. It uses environmentally acceptable solvent, which can easily be separated from the products. In addition, the use of SC-CO2 as a reaction media has also been proposed to eliminate the inhibition limitations that encounter biodiesel production reaction using immobilized enzyme as a catalyst. Furthermore, using SC-CO2 allows easy separation of the product. In this paper, conventional biodiesel production with first generation feedstock, using chemical catalysts and solvent-extraction, is compared to new technologies with an emphasis on using microalgae, immobilized lipase, and SC-CO2 as an extraction solvent and reaction media. PMID:21915372

Effects of hot-water extraction on the thermochemical conversion of shrub willow via fast pyrolysis

USDA-ARS?s Scientific Manuscript database

Hot-water extraction (TM) (HWE) is a pretreatment technology designed to facilitate the subsequent hydrolysis of cellulose by removing the majority of the hemicellulose and ash content from the solid biomass. The HWE process generates salable sugars and other products as part of the process. The bio...

SYNCHROTRON RADIATION, FREE ELECTRON LASER, APPLICATION OF NUCLEAR TECHNOLOGY, ETC. Design of a multi-cusp ion source for proton therapy

NASA Astrophysics Data System (ADS)

Wu, Xiao-Bing; Huang, Tao; Ouyang, Hua-Fu; Zhang, Hua-Shun; Gong, Ke-Yun

2010-12-01

The permanent magnets of the discharge chamber in a multi-cusp proton source are studied and designed. The three electrode extraction system is adopted and simulated. A method to extract different amounts of current while keeping the beam emittance unchanged is proposed.

COMPARISON OF TWO FIELD SAMPLING PROCEDURES (EN CORE AND FIELD METHANOL EXTRACTION) FOR VOLATILE ORGANIC COMPOUNDS

EPA Science Inventory

In-situ Lasagna technology was recently evaluated at a contaminated site at Offutt Air Force Base. The site was contaminated with low levels (< 30 mg/kg) of volatile organic compounds (VOCs). Originally, researchers planned to use field methanol extraction for both pre- and pos...

Green synthesis of silver nanoparticles using Calotropis gigantea and their potential mosquito larvicidal property

USDA-ARS?s Scientific Manuscript database

In recent years the utilization of secondary metabolites from plant extract has emerged as a novel technology for the synthesis of nanoparticles. The aim of the present study was to evaluate the effect of plant synthesized silver nanoparticles (Ag NPs) using aqueous leaf extract of Calotropis gigan...

Technology summary of the in situ bioremediation demonstration (methane biostimulation) via horizontal wells at the Savannah River Site Integrated Demonstration Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hazen, T.C.; Looney, B.B.; Fliermans, C.B.

1994-06-01

The US Department of Energy, Office of Technology Development, has been sponsoring full-scale environmental restoration technology demonstrations for the past 4 years. The Savannah River Site Integrated Demonstration focuses on ``Clean-up of Soils ad Groundwater Contaminated with Chlorinated VOCs.`` Several laboratories including our own had demonstrated the ability of methanotrophic bacteria to completely degrade or mineralize chlorinated solvents, and these bacteria were naturally found in soil and aquifer material. Thus the test consisted of injection of methane mixed with air into the contaminated aquifer via a horizontal well and extraction from the vadose zone via a parallel horizontal well.

Interactions of microorganisms with rare earth ions and their utilization for separation and environmental technology.

PubMed

Moriwaki, Hiroshi; Yamamoto, Hiroki

2013-01-01

In recent years, rare earth elements (REEs) have been widely used in various modern technological devices and the global demand for REE has been increasing. The increased demand for REEs has led to environmental exposure or water pollution from rare earth metal mines and various commercial products. Therefore, the development of a safe technology for the separation and adsorption of REEs is very important from the perspective of green chemistry and environmental pollution. In this review, the application and mechanisms of microorganisms for the removal and extraction of REEs from aqueous solutions are described. In addition, the advantages in using microorganisms for REE adsorption and future studies on this topic are discussed.

A portable foot-parameter-extracting system

NASA Astrophysics Data System (ADS)

Zhang, MingKai; Liang, Jin; Li, Wenpan; Liu, Shifan

2016-03-01

In order to solve the problem of automatic foot measurement in garment customization, a new automatic footparameter- extracting system based on stereo vision, photogrammetry and heterodyne multiple frequency phase shift technology is proposed and implemented. The key technologies applied in the system are studied, including calibration of projector, alignment of point clouds, and foot measurement. Firstly, a new projector calibration algorithm based on plane model has been put forward to get the initial calibration parameters and a feature point detection scheme of calibration board image is developed. Then, an almost perfect match of two clouds is achieved by performing a first alignment using the Sampled Consensus - Initial Alignment algorithm (SAC-IA) and refining the alignment using the Iterative Closest Point algorithm (ICP). Finally, the approaches used for foot-parameterextracting and the system scheme are presented in detail. Experimental results show that the RMS error of the calibration result is 0.03 pixel and the foot parameter extracting experiment shows the feasibility of the extracting algorithm. Compared with the traditional measurement method, the system can be more portable, accurate and robust.

Life cycle analysis on fossil energy ratio of algal biodiesel: effects of nitrogen deficiency and oil extraction technology.

PubMed

Jian, Hou; Jing, Yang; Peidong, Zhang

2015-01-01

Life cycle assessment (LCA) has been widely used to analyze various pathways of biofuel preparation from "cradle to grave." Effects of nitrogen supply for algae cultivation and technology of algal oil extraction on life cycle fossil energy ratio of biodiesel are assessed in this study. Life cycle fossil energy ratio of Chlorella vulgaris based biodiesel is improved by growing algae under nitrogen-limited conditions, while the life cycle fossil energy ratio of biodiesel production from Phaeodactylum tricornutum grown with nitrogen deprivation decreases. Compared to extraction of oil from dried algae, extraction of lipid from wet algae with subcritical cosolvents achieves a 43.83% improvement in fossil energy ratio of algal biodiesel when oilcake drying is not considered. The outcome for sensitivity analysis indicates that the algal oil conversion rate and energy content of algae are found to have the greatest effects on the LCA results of algal biodiesel production, followed by utilization ratio of algal residue, energy demand for algae drying, capacity of water mixing, and productivity of algae.

Identification of New Compounds from Sage Flowers (Salvia officinalis L.) as Markers for Quality Control and the Influence of the Manufacturing Technology on the Chemical Composition and Antibacterial Activity of Sage Flower Extracts.

PubMed

Gericke, Sebastian; Lübken, Tilo; Wolf, Diana; Kaiser, Martin; Hannig, Christian; Speer, Karl

2018-02-28

Parts of Salvia species such as its flowers and leaves are currently used as a culinary herb and for some medicinal applications. To distinguish the different sage extracts it is necessary to analyze their individual chemical compositions. Their characteristic compounds might be established as markers to differentiate between sage flowers and leaf extracts or to determine the manufacturing technology and storage conditions. Tri-p-coumaroylspermidine can be detected only in flowers and has been described here for Salvia and Lavandula species for the first time. Markers for oxidation processes are the novel compounds salviquinone A and B, which were generated from carnosol by exposure to oxygen. Caffeic acid ethyl ester was established as an indirect marker for the usage of ethanol as extraction solvent. The compounds were identified by LC-QTOF-HRESIMS, LC-MS, NMR, IR, and single-crystal X-ray diffraction after isolation by semipreparative HPLC. Furthermore, sage flower resin showed interesting antibacterial in vitro activities against Gram-positive and Gram-negative bacteria.

Hemimorphite Ores: A Review of Processing Technologies for Zinc Extraction

NASA Astrophysics Data System (ADS)

Chen, Ailiang; Li, Mengchun; Qian, Zhen; Ma, Yutian; Che, Jianyong; Ma, Yalin

2016-10-01

With the gradual depletion of zinc sulfide ores, exploration of zinc oxide ores is becoming more and more important. Hemimorphite is a major zinc oxide ore, attracting much attention in the field of zinc metallurgy although it is not the major zinc mineral. This paper presents a critical review of the treatment for extraction of zinc with emphasis on flotation, pyrometallurgical and hydrometallurgical methods based on the properties of hemimorphite. The three-dimensional framework structure of hemimorphite with complex linkage of its structural units lead to difficult desilicification before extracting zinc in the many metallurgical technologies. It is found that the flotation method is generally effective in enriching zinc minerals from hemimorphite ores into a high-grade concentrate for recovery of zinc. Pure zinc can be produced from hemimorphite or/and willemite with a reducing reagent, like methane or carbon. Leaching reagents, such as acid and alkali, can break the complex structure of hemimorphite to release zinc in the leached solution without generation of silica gel in the hydrometallurgical process. For optimal zinc extraction, combing flotation with pyrometallurgical or hydrometallurgical methods may be required.

Life Cycle Analysis on Fossil Energy Ratio of Algal Biodiesel: Effects of Nitrogen Deficiency and Oil Extraction Technology

PubMed Central

Jian, Hou; Jing, Yang; Peidong, Zhang

2015-01-01

Life cycle assessment (LCA) has been widely used to analyze various pathways of biofuel preparation from “cradle to grave.” Effects of nitrogen supply for algae cultivation and technology of algal oil extraction on life cycle fossil energy ratio of biodiesel are assessed in this study. Life cycle fossil energy ratio of Chlorella vulgaris based biodiesel is improved by growing algae under nitrogen-limited conditions, while the life cycle fossil energy ratio of biodiesel production from Phaeodactylum tricornutum grown with nitrogen deprivation decreases. Compared to extraction of oil from dried algae, extraction of lipid from wet algae with subcritical cosolvents achieves a 43.83% improvement in fossil energy ratio of algal biodiesel when oilcake drying is not considered. The outcome for sensitivity analysis indicates that the algal oil conversion rate and energy content of algae are found to have the greatest effects on the LCA results of algal biodiesel production, followed by utilization ratio of algal residue, energy demand for algae drying, capacity of water mixing, and productivity of algae. PMID:26000338

Development of medicine-intended isotope production technologies at Yerevan Physics Institute

NASA Astrophysics Data System (ADS)

Avetisyan, Albert; Avagyan, Robert; Kerobyan, Ivetta; Dallakyan, Ruben; Harutyunyan, Gevorg; Melkonyan, Aleksandr

2015-05-01

Accelerator-based 99mTc and 123I isotopes production technologies were created and developed at A.Alikhanyan National Science Laboratory (former Yerevan Physics Institute - YerPhI). The method involves the irradiation of natural molybdenum (for 99mTc production) and natural xenon (for 123I production) using high-intensity bremsstrahlung photons from the electron beam of the LUE50 linear electron accelerator located at the YerPhI. We have developed and tested the extraction of 99mTc and 123I from the irradiated natural MoO3 and natural Xe, respectively. The production method has been developed and shown to be successful. The current activity is devoted to creation and development of the technology of direct production 99mTc on the 100Mo as target materials using the proton beam from an IBA C18/18 cyclotron. The proton cyclotron C18/18 (producer - IBA, Belgium) was purchased and will be installed nearby AANL (YerPhI) till end 2014. The 18 MeV protons will be used to investigate accelerator-based schemes for the direct production of 99mTc. Main topics of studies will include experimental measurement of 99mTc production yield for different energies of protons, irradiation times, intensities, development of new methods of 99mTc extraction from irradiated materials, development of target preparation technology, development of target material recovery methods for multiple use and others.

Expediting analog design retargeting by design knowledge re-use and circuit synthesis: a practical example on a Delta-Sigma modulator

NASA Astrophysics Data System (ADS)

Webb, Matthew; Tang, Hua

2016-08-01

In the past decade or two, due to constant and rapid technology changes, analog design re-use or design retargeting to newer technologies has been brought to the table in order to expedite the design process and improve time-to-market. If properly conducted, analog design retargeting could significantly cut down design cycle compared to designs starting from the scratch. In this article, we present an empirical and general method for efficient analog design retargeting by design knowledge re-use and circuit synthesis (CS). The method first identifies circuit blocks that compose the source system and extracts the performance parameter specifications of each circuit block. Then, for each circuit block, it scales the values of design variables (DV) from the source design to derive an initial design in the target technology. Depending on the performance of this initial target design, a design space is defined for synthesis. Subsequently, each circuit block is automatically synthesised using state-of-art analog synthesis tools based on a combination of global and local optimisation techniques to achieve comparable performance specifications to those extracted from the source system. Finally, the overall system is composed of those synthesised circuit blocks in the target technology. We illustrate the method using a practical example of a complex Delta-Sigma modulator (DSM) circuit.

Collaboration spotting for dental science.

PubMed

Leonardi, E; Agocs, A; Fragkiskos, S; Kasfikis, N; Le Goff, J M; Cristalli, M P; Luzzi, V; Polimeni, A

2014-10-06

The goal of the Collaboration Spotting project is to create an automatic system to collect information about publications and patents related to a given technology, to identify the key players involved, and to highlight collaborations and related technologies. The collected information can be visualized in a web browser as interactive graphical maps showing in an intuitive way the players and their collaborations (Sociogram) and the relations among the technologies (Technogram). We propose to use the system to study technologies related to Dental Science. In order to create a Sociogram, we create a logical filter based on a set of keywords related to the technology under study. This filter is used to extract a list of publications from the Web of Science™ database. The list is validated by an expert in the technology and sent to CERN where it is inserted in the Collaboration Spotting database. Here, an automatic software system uses the data to generate the final maps. We studied a set of recent technologies related to bone regeneration procedures of oro--maxillo--facial critical size defects, namely the use of Porous HydroxyApatite (HA) as a bone substitute alone (bone graft) or as a tridimensional support (scaffold) for insemination and differentiation ex--vivo of Mesenchymal Stem Cells. We produced the Sociograms for these technologies and the resulting maps are now accessible on--line. The Collaboration Spotting system allows the automatic creation of interactive maps to show the current and historical state of research on a specific technology. These maps are an ideal tool both for researchers who want to assess the state--of--the--art in a given technology, and for research organizations who want to evaluate their contribution to the technological development in a given field. We demonstrated that the system can be used for Dental Science and produced the maps for an initial set of technologies in this field. We now plan to enlarge the set of mapped technologies in order to make the Collaboration Spotting system a useful reference tool for Dental Science research.

Collaboration Spotting for oral medicine.

PubMed

Leonardi, E; Agocs, A; Fragkiskos, S; Kasfikis, N; Le Goff, J M; Cristalli, M P; Luzzi, V; Polimeni, A

2014-09-01

The goal of the Collaboration Spotting project is to create an automatic system to collect information about publications and patents related to a given technology, to identify the key players involved, and to highlight collaborations and related technologies. The collected information can be visualized in a web browser as interactive graphical maps showing in an intuitive way the players and their collaborations (Sociogram) and the relations among the technologies (Technogram). We propose to use the system to study technologies related to oral medicine. In order to create a sociogram, we create a logical filter based on a set of keywords related to the technology under study. This filter is used to extract a list of publications from the Web of Science™ database. The list is validated by an expert in the technology and sent to CERN where it is inserted in the Collaboration Spotting database. Here, an automatic software system uses the data to generate the final maps. We studied a set of recent technologies related to bone regeneration procedures of oro-maxillo-facial critical size defects, namely the use of porous hydroxyapatite (HA) as a bone substitute alone (bone graft) or as a tridimensional support (scaffold) for insemination and differentiation ex vivo of mesenchymal stem cells. We produced the sociograms for these technologies and the resulting maps are now accessible on-line. The Collaboration Spotting system allows the automatic creation of interactive maps to show the current and historical state of research on a specific technology. These maps are an ideal tool both for researchers who want to assess the state-of-the-art in a given technology, and for research organizations who want to evaluate their contribution to the technological development in a given field. We demonstrated that the system can be used in oral medicine as is produced the maps for an initial set of technologies in this field. We now plan to enlarge the set of mapped technologies in order to make the Collaboration Spotting system a useful reference tool for oral medicine research.

Novel treatment technologies for PFAS compounds: A critical review.

PubMed

Kucharzyk, Katarzyna H; Darlington, Ramona; Benotti, Mark; Deeb, Rula; Hawley, Elisabeth

2017-12-15

Perfluorinated compounds such as perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) have recently drawn great attention due to their wide distribution in aquatic environments. The understanding of the physicochemical properties and fate and transport of PFAs in groundwater is still limited. Preliminary studies indicate that these compounds can readily bioaccumulate and pose human and animal health concerns. Due to their physicochemical properties, PFOS and PFOA are water soluble, nonvolatile and persistent in the environment, which is a cause of concern related to their treatment with conventional remediation technologies. Extraction with inefficient carbon adsorption is one of the most common treatment technologies for remediation of PFOS- or PFOA-impacted groundwater. Several other innovative and promising technologies, including sonochemistry, bioremediation and photolysis, have been tested for their effectiveness in removal of perfluorinated compounds. This paper provides a baseline for understanding research needs to better develop treatment technologies for PFOA and PFOS in groundwater. Frontiers for improving the state of practice for PFOA and PFOS treatment include the development of more cost-effective ex situ treatment methods and the development and demonstration of promising in situ treatment technologies at the pilot and full scale. Copyright © 2017 Elsevier Ltd. All rights reserved.

Assuring data transparency through design methodologies

NASA Technical Reports Server (NTRS)

Williams, Allen

1990-01-01

This paper addresses the role of design methodologies and practices in the assurance of technology transparency. The development of several subsystems on large, long life cycle government programs was analyzed to glean those characteristics in the design, development, test, and evaluation that precluded or enabled the insertion of new technology. The programs examined were Minuteman, DSP, B1-B, and space shuttle. All these were long life cycle, technology-intensive programs. The design methodologies (or lack thereof) and design practices for each were analyzed in terms of the success or failure in incorporating evolving technology. Common elements contributing to the success or failure were extracted and compared to current methodologies being proposed by the Department of Defense and NASA. The relevance of these practices to the design and deployment of Space Station Freedom were evaluated. In particular, appropriate methodologies now being used on the core development contract were examined.

Consumer acceptance of technology-based food innovations: lessons for the future of nutrigenomics.

PubMed

Ronteltap, A; van Trijp, J C M; Renes, R J; Frewer, L J

2007-07-01

Determinants of consumer adoption of innovations have been studied from different angles and from the perspectives of various disciplines. In the food area, the literature is dominated by a focus on consumer concern. This paper reviews previous research into acceptance of technology-based innovation from both inside and outside the food domain, extracts key learnings from this literature and integrates them into a new conceptual framework for consumer acceptance of technology-based food innovations. The framework distinguishes 'distal' and 'proximal' determinants of acceptance. Distal factors (characteristics of the innovation, the consumer and the social system) influence consumers' intention to accept an innovation through proximal factors (perceived cost/benefit considerations, perceptions of risk and uncertainty, social norm and perceived behavioural control). The framework's application as a tool to anticipate consumer reaction to future innovations is illustrated for an actual technology-based innovation in food science, nutrigenomics (the interaction between nutrition and human genetics).

1,4-Dioxane Remediation by Extreme Soil Vapor Extraction (XSVE). Screening-Level Feasibility Assessment and Design Tool in Support of 1,4-Dioxane Remediation by Extreme Soil Vapor Extraction (XSVE) ESTCP Project ER 201326

DTIC Science & Technology

2017-10-01

USER GUIDE 1,4-Dioxane Remediation by Extreme Soil Vapor Extraction (XSVE) Screening-Level Feasibility Assessment and Design Tool in...Support of 1,4-Dioxane Remediation by Extreme Soil Vapor Extraction (XSVE) ESTCP Project ER-201326 OCTOBER 2017 Rob Hinchee Integrated Science...Technology, Inc. 1509 Coastal Highway Panacea, FL 32346 8/8/2013 - 8/8/2018 10-2017 1,4-Dioxane Remediation by Extreme Soil Vapor Extraction (XSVE) Screening

Is the extraction by Whatman FTA filter matrix technology and sequencing of large ribosomal subunit D1-D2 region sufficient for identification of clinical fungi?

PubMed

Kiraz, Nuri; Oz, Yasemin; Aslan, Huseyin; Erturan, Zayre; Ener, Beyza; Akdagli, Sevtap Arikan; Muslumanoglu, Hamza; Cetinkaya, Zafer

2015-10-01

Although conventional identification of pathogenic fungi is based on the combination of tests evaluating their morphological and biochemical characteristics, they can fail to identify the less common species or the differentiation of closely related species. In addition these tests are time consuming, labour-intensive and require experienced personnel. We evaluated the feasibility and sufficiency of DNA extraction by Whatman FTA filter matrix technology and DNA sequencing of D1-D2 region of the large ribosomal subunit gene for identification of clinical isolates of 21 yeast and 160 moulds in our clinical mycology laboratory. While the yeast isolates were identified at species level with 100% homology, 102 (63.75%) clinically important mould isolates were identified at species level, 56 (35%) isolates at genus level against fungal sequences existing in DNA databases and two (1.25%) isolates could not be identified. Consequently, Whatman FTA filter matrix technology was a useful method for extraction of fungal DNA; extremely rapid, practical and successful. Sequence analysis strategy of D1-D2 region of the large ribosomal subunit gene was found considerably sufficient in identification to genus level for the most clinical fungi. However, the identification to species level and especially discrimination of closely related species may require additional analysis. © 2015 Blackwell Verlag GmbH.

Integrated use of spatial and semantic relationships for extracting road networks from floating car data

NASA Astrophysics Data System (ADS)

Li, Jun; Qin, Qiming; Xie, Chao; Zhao, Yue

2012-10-01

The update frequency of digital road maps influences the quality of road-dependent services. However, digital road maps surveyed by probe vehicles or extracted from remotely sensed images still have a long updating circle and their cost remain high. With GPS technology and wireless communication technology maturing and their cost decreasing, floating car technology has been used in traffic monitoring and management, and the dynamic positioning data from floating cars become a new data source for updating road maps. In this paper, we aim to update digital road maps using the floating car data from China's National Commercial Vehicle Monitoring Platform, and present an incremental road network extraction method suitable for the platform's GPS data whose sampling frequency is low and which cover a large area. Based on both spatial and semantic relationships between a trajectory point and its associated road segment, the method classifies each trajectory point, and then merges every trajectory point into the candidate road network through the adding or modifying process according to its type. The road network is gradually updated until all trajectories have been processed. Finally, this method is applied in the updating process of major roads in North China and the experimental results reveal that it can accurately derive geometric information of roads under various scenes. This paper provides a highly-efficient, low-cost approach to update digital road maps.

Improved system integration for integrated gasification combined cycle (IGCC) systems.

PubMed

Frey, H Christopher; Zhu, Yunhua

2006-03-01

Integrated gasification combined cycle (IGCC) systems are a promising technology for power generation. They include an air separation unit (ASU), a gasification system, and a gas turbine combined cycle power block, and feature competitive efficiency and lower emissions compared to conventional power generation technology. IGCC systems are not yet in widespread commercial use and opportunities remain to improve system feasibility via improved process integration. A process simulation model was developed for IGCC systems with alternative types of ASU and gas turbine integration. The model is applied to evaluate integration schemes involving nitrogen injection, air extraction, and combinations of both, as well as different ASU pressure levels. The optimal nitrogen injection only case in combination with an elevated pressure ASU had the highest efficiency and power output and approximately the lowest emissions per unit output of all cases considered, and thus is a recommended design option. The optimal combination of air extraction coupled with nitrogen injection had slightly worse efficiency, power output, and emissions than the optimal nitrogen injection only case. Air extraction alone typically produced lower efficiency, lower power output, and higher emissions than all other cases. The recommended nitrogen injection only case is estimated to provide annualized cost savings compared to a nonintegrated design. Process simulation modeling is shown to be a useful tool for evaluation and screening of technology options.

Evaluation of Antioxidant, Antimicrobial, and Antiurolithiatic Potential of Different Solvent Extracts of Aerva lanata Linn Flowers

PubMed Central

Behera, Padma Charan; Ghosh, Manik

2018-01-01

Introduction: Aerva lanata (Linn) of family Amaranthaceae is an important and commonly used plant for its medicinal and pharmacological properties and proving the traditional uses of flowers of A. lanata Linn. Objective: All extracts of A. lanata were further evaluated for antioxidant, antimicrobial, and antiurolithiatic potential to scientifically prove the traditional uses. Materials and Methods: In the present investigation, different solvent extracts of flowers were obtained using a Soxhlet extractor. Microorganisms were obtained from IMTECH, Chandigarh. Antiurolithiatic study was carried out in Albino Research and Training Centre, Hyderabad. Results: Regardless of the antioxidant studied, the methanolic extract presented the highest antioxidant activity and the aqueous extracts offered the lowest, following the order: methanolic extract > ethyl acetate > chloroform > aqueous. The results of this antimicrobial study indicate that methanolic extract of A. lanata could be used as antimicrobial agents. Overall, the methanolic flower extract of A. lanata (Linn) was significantly more promising as antiurolithiatic spectrum. This result also suggested the potential usefulness of the methanolic extract as an antiurolithiatic agent. Conclusion: Henceforward, this research can be acknowledged as a prime new report that focuses on the application of A. lanata (Linn) as an antioxidant, antimicrobial, and antiurolithiatic agent. SUMMARY Overall, methanolic flower extract of Aerva lanata Linn showed promising antioxidant activityAdditionally, methanolic flower extract of A. lanata Linn exhibited remarkable antimicrobial and antiurolithiatic potential. Abbreviations used: IMTECH Chandigarh: Institute of Microbial Technology, Chandigarh; IMMT: Institute of Mineral and Material Technology; CSIR: Council of Scientific & Industrial Research; DPPH: 1,1-diphenyl-2-picrylhydrazyl; MTCC: Microbial Type Culture Collection; BHT: Butylated Hydroxyl Toluene. PMID:29576701

Numerical simulation on reasonable hole-sealing depth of boreholes for gas extraction

NASA Astrophysics Data System (ADS)

Zhao, Dan; Pan, Jingtao

2018-04-01

To overcome the low efficiency of extracting gas in coal reservoirs with a low gas permeability, some boreholes were drilled for gas extraction in No. 2 coal reservoir of Wangjialing Coalmine in Shanxi Province, China and reasonably sealed. Aiming at shortfalls such as rapid attenuation of volume for extracted gas as well as low gas permeability when using boreholes in the No. 2 coal reservoir, the traditional COMSOL MultiphysicsMT Earth Science Module was used to couple the three governing equations (Darcy-Brinkman-Navier-Stokes) for fluids. On this basis, numerical simulation on the seepage law along the directions of roadways and boreholes was carried out. The simulation results indicated that when the hole-sealing length was within the width range of fractures in roadways, the negative pressure not only led the gas in surrounding rock masses to flow to the boreholes, but also made the air flow in roadways to permeate into coal walls. As a result, gas and air flows both entered into the boreholes through the loosening zone containing fractures, resulting in seepage of air in roadway to the boreholes. The seepage velocity along the roadway direction under condition with a hole-sealing length of 12 m was obviously slower than that when the hole-sealing length was 8 m. While, the method by simply increasing the length of the hole-sealing section for boreholes failed to effectively stop the air flow in roadways from permeating into the coal wall and then entering the boreholes. Moreover, the increase in the hole-sealing length brought about much more difficulties to the hole-sealing construction. So, the method is not operable in practical condition of the coal mine. Therefore, it is necessary to improve the traditional hole-sealing technology based on foamed macromolecular materials which are mainly made of polyurethane (PU) and use the fluid wall-type hole-sealing technology based on solid-liquid coupling. Then, the effects of gas extraction before and after using the fluid wall-type hole-sealing technology based on solid-liquid coupling to increase the hole-sealing length to 12 m were compared. The comparison results revealed that the pure extraction amount of gas from a single borehole in the No. 2 coal reservoir of Wangjialing Coalmine was improved by 4˜6 times. In addition, the concentration of extracted gas increased from less than 1% under the traditional hole-sealing mode to 20%˜25%, with an increase of more than 20 times. The extraction effect of the No. 2 coal reservoir of the coal mine was significantly enhanced by employing the fluid-wall-type hole-sealing technology based on solid-liquid coupling.

Physical, technical, and economic accessibility of resources and reserves need to be distinguished by grade: Application to the case of phosphorus.

PubMed

Springer, Nathaniel P

2017-01-15

The amount of phosphorus in the total environment is finite, yet recent estimates suggest that more than enough phosphate ore resources exist in the lithosphere to meet future increases in demand during the next century. Still, it remains unclear how the accessibility of this resource stock - which is heterogeneous in terms of grade and location - will change as currently accessible resources are utilized, as extraction and processing technologies develop, and as the relative economic costs vary. This study uses an economic framework, the World Trade Model with Rectangular Choice-of-Technology, to link estimates of known geological resources of various grades with the technically and economically accessible reserves. Using the most recent public data on phosphate ore stocks and mining and technological capacity, this study estimates that the ~400,000teragrams (Tg) of known apatite ore (>1% P 2 O 5 content) equate to ~110,000Tg when converted to potential reserves (~30% P 2 O 5 ) using existing technologies, with over half of these remaining potential reserves converted from resources with grades below 20% P 2 O 5 . Corresponding global reserves are estimated at ~70,000Tg using the Rectangular Choice-of-Technology model, but since any reserve estimate is contingent on the state of the world economy, a set of five illustrative scenarios are constructed to show how this estimate can vary between ~67,000 and ~98,000Tg with only a small number of changes to the economic and technical parameters and variables. Calculating accessibility using consistent definitions for resources and reserves while distinguishing between grades not only creates a clearer picture of remaining non-renewable resources, but creates a framework that can be used to explore future geopolitical scenarios about ore availability, extraction technologies, supply networks, and global commodity prices. Copyright © 2016 Elsevier B.V. All rights reserved.

A new generation of medical cyclotrons for the 90`s

DOE Office of Scientific and Technical Information (OSTI.GOV)

Milton, B.F.

1995-08-01

Cyclotrons continue to be efficient accelerators for use in radio-isotope production. In recent years, developments in accelerator technology have greatly increased the practical beam current in these machines while also improving the overall system reliability. These developments combined with the development of new isotopes for medicine and industry, and a retiring of older machines indicates a strong future for commercial cyclotrons. In this paper the authors will survey recent developments in the areas of cyclotron technology as they relate to the new generation of commercial cyclotrons. Existing and potential markets for these cyclotrons will be presented. They will also discussmore » the possibility of systems capable of extracted energies up to 150 MeV and extracted beam currents of up to 2.0 mA.« less

[Study on spray-drier preparation technology of weitai granules using orthogonal experiments].

PubMed

Qu, Cai-Hong; Yang, Li; Chen, Zhi-Liang

2006-04-01

To screen preparation technique in order to raise the end-product and economical efficiency of spray-drier preparation technology of weitai granules. Newly Fluid-bed-spray-drier-granulation technique was adoped and taken extracting technique, temperature of exit and entry and the matching of accessories as inspecting factors, two levels of each factors, end-product and the water content of semi-finished weitai granules as inspecting marker, the best preparation technique of weitai granules was screened by orthogonal desing. Among the 3 factors, the matching of accessories was most notalbe (P < 0.01), next was the temperature of exit and entry (P < 0.05). However, the extracting technique was of little importance (P > 0.05). The optimum spray-drier granulation technique of weitai granules is A3B1C3.

Extraction and Analysis of Traditional Chinese Medicine Crops Based on Multitemporal High Resolution Data-Taking Qiaocheng District of Bozhou as AN Example

NASA Astrophysics Data System (ADS)

Yu, H.; He, J.; Zhou, H.; Guan, F.; Li, L.; Ren, B.; Wang, Z.

2018-04-01

Remote sensing technology has become an important method to rapidly acquireing of planting layout and composition of regional crops.It is very important to accurately master the planting area of Chinese medicine crops in the Characteristic planting area because it relations to accurately master the cultivation of Chinese medicine crops, formulate related policies and adjustment of crop planting structure.The author puts forward a method of using remote sencing technology for momitoring Chinese medicine which has good applicability and generalization. This paper took Qiaocheng District of Bozhou as an example to Verify the feasibility of the method, providing a reference for solving the problem of interpretation and extraction of Chinese medicinal materials in the region.

Plasma-Treated Microplates with Enhanced Protein Recoveries and Minimized Extractables

PubMed Central

Weikart, Christopher M.; Klibanov, Alexander M.; Breeland, Adam P.; Taha, Ahmad H.; Maurer, Brian R.; Martin, Steven P.

2016-01-01

SiO2 Medical Products, Inc. (SiO) has developed a proprietary technology that greatly enhances protein recoveries and reduces extractables from commercial microplates used for bioanalytical assays and storage of biologics. SiO technology is based on plasma treatment that chemically modifies the surface of polypropylene with predominantly hydrogen-bond-acceptor uncharged polar groups. The resultant surface resists nonspecific protein adsorption over a wide range of protein concentrations, thereby eliminating the need to passivate (and hence potentially contaminate) the microplates with blocking proteins. High shelf-life stability and cleanliness of the plasma-treated microplates have been demonstrated using five different proteins for two common microplate formats. The protein recovery performance of plasma-treated microplates is found to be higher compared with commercial low-protein-binding microplates. PMID:27651466

A systematic review of portable electronic technology for health education in resource-limited settings.

PubMed

McHenry, Megan S; Fischer, Lydia J; Chun, Yeona; Vreeman, Rachel C

2017-08-01

The objective of this study is to conduct a systematic review of the literature of how portable electronic technologies with offline functionality are perceived and used to provide health education in resource-limited settings. Three reviewers evaluated articles and performed a bibliography search to identify studies describing health education delivered by portable electronic device with offline functionality in low- or middle-income countries. Data extracted included: study population; study design and type of analysis; type of technology used; method of use; setting of technology use; impact on caregivers, patients, or overall health outcomes; and reported limitations. Searches yielded 5514 unique titles. Out of 75 critically reviewed full-text articles, 10 met inclusion criteria. Study locations included Botswana, Peru, Kenya, Thailand, Nigeria, India, Ghana, and Tanzania. Topics addressed included: development of healthcare worker training modules, clinical decision support tools, patient education tools, perceptions and usability of portable electronic technology, and comparisons of technologies and/or mobile applications. Studies primarily looked at the assessment of developed educational modules on trainee health knowledge, perceptions and usability of technology, and comparisons of technologies. Overall, studies reported positive results for portable electronic device-based health education, frequently reporting increased provider/patient knowledge, improved patient outcomes in both quality of care and management, increased provider comfort level with technology, and an environment characterized by increased levels of technology-based, informal learning situations. Negative assessments included high investment costs, lack of technical support, and fear of device theft. While the research is limited, portable electronic educational resources present promising avenues to increase access to effective health education in resource-limited settings, contingent on the development of culturally adapted and functional materials to be used on such devices.

Olive oil pilot-production assisted by pulsed electric field: impact on extraction yield, chemical parameters and sensory properties.

PubMed

Puértolas, Eduardo; Martínez de Marañón, Iñigo

2015-01-15

The impact of the use of pulsed electric field (PEF) technology on Arroniz olive oil production in terms of extraction yield and chemical and sensory quality has been studied at pilot scale in an industrial oil mill. The application of a PEF treatment (2 kV/cm; 11.25 kJ/kg) to the olive paste significantly increased the extraction yield by 13.3%, with respect to a control. Furthermore, olive oil obtained by PEF showed total phenolic content, total phytosterols and total tocopherols significantly higher than control (11.5%, 9.9% and 15.0%, respectively). The use of PEF had no negative effects on general chemical and sensory characteristics of the olive oil, maintaining the highest quality according to EU legal standards (EVOO; extra virgin olive oil). Therefore, PEF could be an appropriate technology to improve olive oil yield and produce EVOO enriched in human-health-related compounds, such as polyphenols, phytosterols and tocopherols. Copyright © 2014 Elsevier Ltd. All rights reserved.

Automatic updating and 3D modeling of airport information from high resolution images using GIS and LIDAR data

NASA Astrophysics Data System (ADS)

Lv, Zheng; Sui, Haigang; Zhang, Xilin; Huang, Xianfeng

2007-11-01

As one of the most important geo-spatial objects and military establishment, airport is always a key target in fields of transportation and military affairs. Therefore, automatic recognition and extraction of airport from remote sensing images is very important and urgent for updating of civil aviation and military application. In this paper, a new multi-source data fusion approach on automatic airport information extraction, updating and 3D modeling is addressed. Corresponding key technologies including feature extraction of airport information based on a modified Ostu algorithm, automatic change detection based on new parallel lines-based buffer detection algorithm, 3D modeling based on gradual elimination of non-building points algorithm, 3D change detecting between old airport model and LIDAR data, typical CAD models imported and so on are discussed in detail. At last, based on these technologies, we develop a prototype system and the results show our method can achieve good effects.

Potential Impacts of Hydrokinetic and Wave Energy Conversion Technologies on Aquatic Environments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Čada, Glenn F.

2007-04-01

A new generation of hydropower technologies, the kinetic hydro and wave energy conversion devices, offers the possibility of generating electricity from the movements of water, without the need for dams and diversions. The Energy Policy Act of 2005 encouraged the development of these sources of renewable energy in the United States, and there is growing interest in deploying them globally. The technologies that would extract electricity from free-flowing streams, estuaries, and oceans have not been widely tested. Consequently, the U.S. Department of Energy convened a workshop to (1) identify the varieties of hydrokinetic energy and wave energy conversion devices andmore » their stages of development, (2) identify where these technologies can best operate, (3) identify the potential environmental issues associated with these technologies and possible mitigation measures, and (4) develop a list of research needs and/or practical solutions to address unresolved environmental issues. The article reviews the results of that workshop, focusing on potential effects on freshwater, estuarine, and marine ecosystems, and we describe recent national and international developments.« less

Automatic Speech Acquisition and Recognition for Spacesuit Audio Systems

NASA Technical Reports Server (NTRS)

Ye, Sherry

2015-01-01

NASA has a widely recognized but unmet need for novel human-machine interface technologies that can facilitate communication during astronaut extravehicular activities (EVAs), when loud noises and strong reverberations inside spacesuits make communication challenging. WeVoice, Inc., has developed a multichannel signal-processing method for speech acquisition in noisy and reverberant environments that enables automatic speech recognition (ASR) technology inside spacesuits. The technology reduces noise by exploiting differences between the statistical nature of signals (i.e., speech) and noise that exists in the spatial and temporal domains. As a result, ASR accuracy can be improved to the level at which crewmembers will find the speech interface useful. System components and features include beam forming/multichannel noise reduction, single-channel noise reduction, speech feature extraction, feature transformation and normalization, feature compression, and ASR decoding. Arithmetic complexity models were developed and will help designers of real-time ASR systems select proper tasks when confronted with constraints in computational resources. In Phase I of the project, WeVoice validated the technology. The company further refined the technology in Phase II and developed a prototype for testing and use by suited astronauts.

A New Approach to Geoengineering: Manna From Heaven

NASA Astrophysics Data System (ADS)

Ellery, Alex

2015-04-01

Geo-engineering, although controversial, has become an emerging factor in coping with climate change. Although most are terrestrial-based technologies, I focus on a space-based approach implemented through a solar shield system. I present several new elements that essentially render the high-cost criticism moot. Of special relevance are two seemingly unrelated technologies - the Resource Prospector Mission (RPM) to the Moon in 2018 that shall implement a technology demonstration of simple material resource extraction from lunar regolith, and the emergence of multi-material 3D printing technology that promises unprecedented robotic manufacturing capabilities. My research group has begun theoretical and experimentation work in developing the concept of a 3D printed electric motor system from lunar-type resources. The electric motor underlies every universal mechanical machine. Together with 3D printed electronics, I submit that this would enable self-replicating machines to be realised. A detailed exposition on how this may be achieved will be outlined. Such self-replicating machines could construct the spacecraft required to implement a solar shield and solar power satellites in large numbers from lunar resources with the same underlying technologies at extremely low cost.

Enhancing Ear and Hearing Health Access for Children With Technology and Connectivity.

PubMed

Swanepoel, De Wet

2017-10-12

Technology and connectivity advances are demonstrating increasing potential to improve access of service delivery to persons with hearing loss. This article demonstrates use cases from community-based hearing screening and automated diagnosis of ear disease. This brief report reviews recent evidence for school- and home-based hearing testing in underserved communities using smartphone technologies paired with calibrated headphones. Another area of potential impact facilitated by technology and connectivity is the use of feature extraction algorithms to facilitate automated diagnosis of most common ear conditions from video-otoscopic images. Smartphone hearing screening using calibrated headphones demonstrated equivalent sensitivity and specificity for school-based hearing screening. Automating test sequences with a forced-choice response paradigm allowed persons with minimal training to offer screening in underserved communities. The automated image analysis and diagnosis system for ear disease demonstrated an overall accuracy of 80.6%, which is up to par and exceeds accuracy rates previously reported for general practitioners and pediatricians. The emergence of these tools that capitalize on technology and connectivity advances enables affordable and accessible models of service delivery for community-based ear and hearing care.

Medical technology as a key driver of rising health expenditure: disentangling the relationship

PubMed Central

Sorenson, Corinna; Drummond, Michael; Bhuiyan Khan, Beena

2013-01-01

Health care spending has risen steadily in most countries, becoming a concern for decision-makers worldwide. Commentators often point to new medical technology as the key driver for burgeoning expenditures. This paper critically appraises this conjecture, based on an analysis of the existing literature, with the aim of offering a more detailed and considered analysis of this relationship. Several databases were searched to identify relevant literature. Various categories of studies (eg, multivariate and cost-effectiveness analyses) were included to cover different perspectives, methodological approaches, and issues regarding the link between medical technology and costs. Selected articles were reviewed and relevant information was extracted into a standardized template and analyzed for key cross-cutting themes, ie, impact of technology on costs, factors influencing this relationship, and methodological challenges in measuring such linkages. A total of 86 studies were reviewed. The analysis suggests that the relationship between medical technology and spending is complex and often conflicting. Findings were frequently contingent on varying factors, such as the availability of other interventions, patient population, and the methodological approach employed. Moreover, the impact of technology on costs differed across technologies, in that some (eg, cancer drugs, invasive medical devices) had significant financial implications, while others were cost-neutral or cost-saving. In light of these issues, we argue that decision-makers and other commentators should extend their focus beyond costs solely to include consideration of whether medical technology results in better value in health care and broader socioeconomic benefits. PMID:23807855

Extract-filter-shoot liquid chromatography/mass spectrometry for analysis of vitamin D2 in a powdered supplement capsule and SRM 3280

USDA-ARS?s Scientific Manuscript database

An ‘extract-filter-shoot’ method for analysis of vitamin D2, ergocalciferol, in a dry powdered dietary supplement capsule containing rice flour excipient and in National Institute of Standards and Technology (NIST) standard reference material (SRM) 3280 is reported. Quantification of vitamin D2 was...

The value of information technology in healthcare.

PubMed

Skinner, Richard I

2003-01-01

Not only will healthcare investments in information technology (IT) continue, they are sure to increase. Just as other industries learned over time how to extract more value from IT investments, so too will the healthcare industry, and for the same reason: because they must. This article explores the types of business value IT has generated in other industries, what value it can generate in healthcare, and some of the barriers encountered in achieving that value. The article ends with management principles for IT investment.

ELECTROKINETIC REMEDIATION: BASICS AND TECHNOLOGY STATUS

EPA Science Inventory

Electrokinetic remediation, variably named as electrochemical soil processing, electromigration, electrokinetic decontamination or electroreclamation uses electric currents to extract radionuclides, heavy metals, certain organic compounds, or mixed inorganic species and some orga...

Information Extraction from Unstructured Text for the Biodefense Knowledge Center

DOE Office of Scientific and Technical Information (OSTI.GOV)

Samatova, N F; Park, B; Krishnamurthy, R

2005-04-29

The Bio-Encyclopedia at the Biodefense Knowledge Center (BKC) is being constructed to allow an early detection of emerging biological threats to homeland security. It requires highly structured information extracted from variety of data sources. However, the quantity of new and vital information available from every day sources cannot be assimilated by hand, and therefore reliable high-throughput information extraction techniques are much anticipated. In support of the BKC, Lawrence Livermore National Laboratory and Oak Ridge National Laboratory, together with the University of Utah, are developing an information extraction system built around the bioterrorism domain. This paper reports two important pieces ofmore » our effort integrated in the system: key phrase extraction and semantic tagging. Whereas two key phrase extraction technologies developed during the course of project help identify relevant texts, our state-of-the-art semantic tagging system can pinpoint phrases related to emerging biological threats. Also we are enhancing and tailoring the Bio-Encyclopedia by augmenting semantic dictionaries and extracting details of important events, such as suspected disease outbreaks. Some of these technologies have already been applied to large corpora of free text sources vital to the BKC mission, including ProMED-mail, PubMed abstracts, and the DHS's Information Analysis and Infrastructure Protection (IAIP) news clippings. In order to address the challenges involved in incorporating such large amounts of unstructured text, the overall system is focused on precise extraction of the most relevant information for inclusion in the BKC.« less

Evaluation of cell lysis procedures and use of a micro fluidic system for an automated DNA-based cell identification in interplanetary missions

NASA Astrophysics Data System (ADS)

Hall, J. A.; Felnagle, E.; Fries, M.; Spearing, S.; Monaco, L.; Steele, A.

2006-12-01

A Modular Assay System for Solar System Exploration (MASSE) is being developed to include sample handling, pre-treatment, separation and analysis of biological target compounds by both DNA and protein microarrays. To better design sensitive and accurate initial upstream sample handling of the MASSE instrument, experiments investigating the sensitivity and potential extraction bias of commercially available DNA extraction kits between classes of environmentally relevant prokaryotes such as gram-negative bacteria ( Escherichia coli), gram-positive bacteria ( Bacillus megatarium), and Archaea ( Haloarcula marismortui) were performed. For extractions of both planktonic cultures and spiked Mars simulated regolith, FTA ® paper demonstrated the highest sensitivity, with detection as low as ˜1×10 1 cells and ˜3.3×10 2 cells, respectively. In addition to the highest sensitivity, custom modified application of FTA ® paper extraction protocol is the simplest in terms of incorporation into MASSE and displayed little bias in sensitivity with respect to prokaryotic cell type. The implementation of FTA paper for environmental microbiology investigations appears to be a viable and effective option potentially negating the need for other pre-concentration steps such as filtration and negating concerns regarding extraction efficiency of cells. In addition to investigations on useful technology for upstream sample handling in MASSE, we have also evaluated the potential for μTAS to be employed in the MASSE instrument by employing proprietary lab-on-a-chip development technology to investigate the potential for microfluidic cell lysis of different prokaryotic cells employing both chemical and biological lysis agents. Real-time bright-field microscopy and quantitative PMT detection indicated that that gram positive, gram negative and archaeal cells were effectively lyzed in a few seconds using the microfluidic chip protocol developed. This included employing a lysis buffer with components including lysozyme, Protease, Proteinase K, Tween-20 and TritonX-100. The effectiveness of antibiotics and other chemical lysis agents were also screened and demonstrated partial effectiveness on all three cell types. This work demonstrates a step wise approach to evaluating the efficacy and sensitivity of commercial macro-scale technology and state-of-the-art developmental microfluidic technology under consideration for incorporation into the remotely operated MASSE instrument currently under development at the Carnegie Institution of Washington.

Managing diabetes mellitus using information technology: a systematic review.

PubMed

Riazi, H; Larijani, B; Langarizadeh, M; Shahmoradi, L

2015-01-01

To review published evidences about using information technology interventions in diabetes care and determine their effects on managing diabetes. Systematic review of information technology based interventions. MEDLINE®/PubMed were electronically searched for articles published between 2004/07/01 and 2014/07/01. A comprehensive, electronic search strategy was used to identify eligible articles. Inclusion criteria were defined based on type of study and effect of information technology based intervention in relation to glucose control and other clinical outcomes in diabetic patients. Studies must have used a controlled design to evaluate an information technology based intervention. A total of 3613 articles were identified based on the searches conducted in MEDLINE from PubMed. After excluding duplicates (n = 6), we screened titles and abstracts of 3607 articles based on inclusion criteria. The remaining articles matched with inclusion criteria (n = 277) were reviewed in full text, and 210 articles were excluded based on exclusion criteria. Finally, 67 articles complied with our eligibility criteria and were included in this study. In this study, the effect of various information technology based interventions on clinical outcomes in diabetic patients extracted and measured from selected articles is described and compared to each other. Information technology based interventions combined with the usual care are associated with improved glycemic control with different efficacy on various clinical outcomes in diabetic patients.

New technology of functional infrared imaging and its clinical applications

NASA Astrophysics Data System (ADS)

Yang, Hongqin; Xie, Shusen; Lu, Zukang; Liu, Zhongqi

2006-01-01

With improvements in infrared camera technology, the promise of reduced costs and noninvasive character, infrared thermal imaging resurges in medicine. The paper introduces a new technology of functional infrared imaging, thermal texture maps (TTM), which is not only an apparatus for thermal radiation imaging but also a new method for revealing the relationship between the temperature distribution of the skin surface and the emission field inside body. The skin temperature distribution of a healthy human body exhibits a contralateral symmetry. Any disease in the body is associated with an alteration of the thermal distribution of human body. Infrared thermography is noninvasive, so it is the best choice for studying the physiology of thermoregulation and the thermal dysfunction associated with diseases. Reading and extracting information from the thermograms is a complex and subjective task that can be greatly facilitated by computerized techniques. Through image processing and measurement technology, surface or internal radiation sources can be non-invasively distinguished through extrapolation. We discuss the principle, the evaluation procedure and the effectiveness of TTM technology in the clinical detection and diagnosis of cancers, especially in their early stages and other diseases by comparing with other imaging technologies, such as ultrasound. Several study cases are given to show the effectiveness of this method. At last, we point out the applications of TTM technology in the research field of traditional medicine.

Deep Aquifer Remediation Tools (DARTs): A new technology for ground-water remediation

USGS Publications Warehouse

Naftz, David L.; Davis, James A.

1999-01-01

Potable ground-water supplies throughout the world are contaminated or threatened by advancing plumes containing radionuclides, metals, and organic compounds. Currently (1999), the most widely used method of ground-water remediation is a combination of extraction, ex-situ treatment, and discharge of the treated water, commonly known as pump and treat. Pump-and-treat methods are costly and often ineffective in meeting long-term protection standards (Travis and Doty, 1990; Gillham and Burris, 1992; National Research Council, 1994). This fact sheet describes a new and potentially cost-effective technology for removal of organic and inorganic contaminants from ground water. The U.S. Geological Survey (USGS) is currently exploring the possibilities of obtaining a U.S. Patent for this technology.

Accelerating Innovation that Enhances Resource Recovery in the Wastewater Sector: Advancing a National Testbed Network.

PubMed

Mihelcic, James R; Ren, Zhiyong Jason; Cornejo, Pablo K; Fisher, Aaron; Simon, A J; Snyder, Seth W; Zhang, Qiong; Rosso, Diego; Huggins, Tyler M; Cooper, William; Moeller, Jeff; Rose, Bob; Schottel, Brandi L; Turgeon, Jason

2017-07-18

This Feature examines significant challenges and opportunities to spur innovation and accelerate adoption of reliable technologies that enhance integrated resource recovery in the wastewater sector through the creation of a national testbed network. The network is a virtual entity that connects appropriate physical testing facilities, and other components needed for a testbed network, with researchers, investors, technology providers, utilities, regulators, and other stakeholders to accelerate the adoption of innovative technologies and processes that are needed for the water resource recovery facility of the future. Here we summarize and extract key issues and developments, to provide a strategy for the wastewater sector to accelerate a path forward that leads to new sustainable water infrastructures.

PROJECT W-551 DETERMINATION DATA FOR EARLY LAW INTERIM PRETREATMENT SYSTEM SELECTION

DOE Office of Scientific and Technical Information (OSTI.GOV)

TEDESCHI AR

This report provides the detailed assessment forms and data for selection of the solids separation and cesium separation technology for project W-551, Interim Pretreatment System. This project will provide early pretreated low activity waste feed to the Waste Treatment Plant to allow Waste Treatment Plan Low Activity Waste facility operation prior to construction completion of the Pretreatment and High Level Waste facilities. The candidate solids separations technologies are rotary microfiltration and crossflow filtration, and the candidate cesium separation technologies are fractional crystallization, caustic-side solvent extraction, and ion-exchange using spherical resorcinol-formaldehyde resin. This data was used to prepare a cross-cutting technologymore » summary, reported in RPP-RPT-37740.« less

Advanced space power requirements and techniques. Task 1: Mission projections and requirements. Volume 1: Technical report

NASA Technical Reports Server (NTRS)

Wolfe, M. G.

1978-01-01

The objectives of this study were to: (1) develop projections of the NASA, DoD, and civil space power requirements for the 1980-1995 time period; (2) identify specific areas of application and space power subsystem type needs for each prospective user; (3) document the supporting and historical base, including relevant cost related measures of performance; and (4) quantify the benefits of specific technology projection advancements. The initial scope of the study included: (1) construction of likely models for NASA, DoD, and civil space systems; (2) generation of a number of future scenarios; (3) extraction of time phased technology requirements based on the scenarios; and (4) cost/benefit analyses of some of the technologies identified.

Carbon footprint assessment of recycling technologies for rare earth elements: A case study of recycling yttrium and europium from phosphor.

PubMed

Hu, Allen H; Kuo, Chien-Hung; Huang, Lance H; Su, Chao-Chin

2017-02-01

Rare earth elements are key raw materials in high-technology industries. Mining activities and manufacturing processes of such industries have caused considerable environmental impacts, such as soil erosion, vegetation destruction, and various forms of pollution. Sustaining the long-term supply of rare earth elements is difficult because of the global shortage of rare earth resources. The diminishing supply of rare earth elements has attracted considerable concern because many industrialized countries regarded such elements as important strategic resources for economic growth. This study aims to explore the carbon footprints of yttrium and europium recovery techniques from phosphor. Two extraction recovery methods, namely, acid extraction and solvent extraction, were selected for the analysis and comparison of carbon footprints. The two following functional units were used: (1) the same phosphor amounts for specific Y and Eu recovery concentrations, and (2) the same phosphor amounts for extraction. For acid extraction method, two acidic solutions (H 2 SO 4 and HCl) were used at two different temperatures (60 and 90°C). For solvent extraction method, acid leaching was performed followed by ionic liquid extraction. Carbon footprints from acid and solvent extraction methods were estimated to be 10.1 and 10.6kgCO 2 eq, respectively. Comparison of the carbon emissions of the two extraction methods shows that the solvent extraction method has significantly higher extraction efficiency, even though acid extraction method has a lower carbon footprint. These results may be used to develop strategies for life cycle management of rare earth resources to realize sustainable usage. Copyright © 2016 Elsevier Ltd. All rights reserved.

The Hydrometallurgical Extraction and Recovery of High-Purity Silver

NASA Astrophysics Data System (ADS)

Hoffmann, James E.

2012-06-01

With the continuous reduction in the availability of extractive metallurgical curricula in colleges and universities, the concern has in part been from where will the next generation of extractive metallurgists come? One objective of this article is to emphasize the fact that extractive metallurgy is, in fact, one of many areas of chemical engineering technology. Thus, although the extractive metallurgist may have disappeared in name, its activity is alive and well, subsumed in the field of chemical engineering. One goal of this lecture is to demonstrate the applicability of chemical engineering principles to what is typically considered "the field of extractive metallurgy." Two processes will be described that have supplanted typical pyrometallurgical fire refining of precious metals, particularly silver. The origins of fire refining can be traced back to biblical times. There are numerous references to it in the old testament: Ezekiel 22:20, "As men gather silver and bronze and iron and lead and tin into a furnace to blow the fire upon it in order melt it"; Jeremiah 6:29, "The bellows blow fiercely; the lead is consumed by the fire; in vain the refining goes on"; and Malachi 3:2 (The Oxford Annotated Bible with the Apocrypha), "For he is like a refiners fire." Many references to it will also be found in "De Re Metallurgica" and as well in Lazarus Ercker's 1574 Manual "Treatise on Ores and Refining." Today, fire refining has been improved greatly by innovative furnace design, new fluxing technologies, and the improved use of oxygen. However, fundamentally, the process chemistry has not changed much in the last millennium. Illustrations of hydrometallurgical processing of silver-bearing inputs will be provided by the treatment of sulfated silver-bearing materials and chlorinated slimes. The first of these technologies will be described briefly as practiced by the Phelps Dodge Refining Corporation for several years. The second, the treatment of silver chloride-bearing inputs, will be described in detail to demonstrate how typical chemical engineering unit process and unit operations have supplanted classic smelting and fire refining techniques. The Kennecott Copper Company, which has operated a hydrometallurgical circuit successfully for the recovery of high-purity silver from the slimes wet chlorination residue, has permitted me to provide some operation information and results using the technology. Both Phelps Dodge and Kennecott should be recognized for their forward-looking attitude in undertaking the conversion of conceptual chemistry into successful, full-scale plants. The process as employed at Phelps Dodge is discussed at length in reference (J.E. Hoffmann and B. Wesstrom: Hydrometallurgy, 1994, vol. 94, pp. 69-105).

Associating Human-Centered Concepts with Social Networks Using Fuzzy Sets

NASA Astrophysics Data System (ADS)

Yager, Ronald R.

The rapidly growing global interconnectivity, brought about to a large extent by the Internet, has dramatically increased the importance and diversity of social networks. Modern social networks cut across a spectrum from benign recreational focused websites such as Facebook to occupationally oriented websites such as LinkedIn to criminally focused groups such as drug cartels to devastation and terror focused groups such as Al-Qaeda. Many organizations are interested in analyzing and extracting information related to these social networks. Among these are governmental police and security agencies as well marketing and sales organizations. To aid these organizations there is a need for technologies to model social networks and intelligently extract information from these models. While established technologies exist for the modeling of relational networks [1-7] few technologies exist to extract information from these, compatible with human perception and understanding. Data bases is an example of a technology in which we have tools for representing our information as well as tools for querying and extracting the information contained. Our goal is in some sense analogous. We want to use the relational network model to represent information, in this case about relationships and interconnections, and then be able to query the social network using intelligent human-centered concepts. To extend our capabilities to interact with social relational networks we need to associate with these network human concepts and ideas. Since human beings predominantly use linguistic terms in which to reason and understand we need to build bridges between human conceptualization and the formal mathematical representation of the social network. Consider for example a concept such as "leader". An analyst may be able to express, in linguistic terms, using a network relevant vocabulary, properties of a leader. Our task is to translate this linguistic description into a mathematical formalism that allows us to determine how true it is that a particular node is a leader. In this work we look at the use of fuzzy set methodologies [8-10] to provide a bridge between the human analyst and the formal model of the network.

[A technological study on the extraction of ultra-fine powder of Panax notoginsen].

PubMed

Huang, Yaohai; Huang, Mingqing; Zeng, Huifang; Guo, Wei; Xi, Ping

2005-12-01

To investigate the extraction of ultra-fine powder Panax notoginsen. The extraction rate of ginseng saponin Rg1, Re, Rb1, notoginseng saponin R1 and filtrated time were determined by alcoholic and aqueous extraction of Panax notoginsen in tablet, coarse powder, ultra-fine powder and recostitution granules of ultra-fine powder. The filtered time of ultra-fine powder of Panax notoginsen extraction and that of the tablet of Panax notoginsen extraction were similar, while the extraction rates of various saponins of it were high. The method of aqueous extrction in ltra-fine powder of Panax notoginsen is easy in filtrationer, higher in extraction rate of Panax notoginsen and lower in production cost.

Forensic print extraction using 3D technology and its processing

NASA Astrophysics Data System (ADS)

Rajeev, Srijith; Shreyas, Kamath K. M.; Panetta, Karen; Agaian, Sos S.

2017-05-01

Biometric evidence plays a crucial role in criminal scene analysis. Forensic prints can be extracted from any solid surface such as firearms, doorknobs, carpets and mugs. Prints such as fingerprints, palm prints, footprints and lip-prints can be classified into patent, latent, and three-dimensional plastic prints. Traditionally, law enforcement officers capture these forensic traits using an electronic device or extract them manually, and save the data electronically using special scanners. The reliability and accuracy of the method depends on the ability of the officer or the electronic device to extract and analyze the data. Furthermore, the 2-D acquisition and processing system is laborious and cumbersome. This can lead to the increase in false positive and true negative rates in print matching. In this paper, a method and system to extract forensic prints from any surface, irrespective of its shape, is presented. First, a suitable 3-D camera is used to capture images of the forensic print, and then the 3-D image is processed and unwrapped to obtain 2-D equivalent biometric prints. Computer simulations demonstrate the effectiveness of using 3-D technology for biometric matching of fingerprints, palm prints, and lip-prints. This system can be further extended to other biometric and non-biometric modalities.

Transcriptional effect of an Aframomum angustifolium seed extract on human cutaneous cells using low-density DNA chips.

PubMed

Bonnet-Duquennoy, Mathilde; Dumas, Marc; Debacker, Adeline; Lazou, Kristell; Talbourdet, Sylvie; Franchi, Jocelyne; Heusèle, Catherine; André, Patrice; Schnebert, Sylvianne; Bonté, Frédéric; Kurfürst, Robin

2007-06-01

Studying photoexposed and photoprotected skin biopsies from young and aged women, it has been found that a specific zone, composed of the basal layers of the epidermis, the dermal epidermal junction, and the superficial dermis, is major target of aging and reactive oxygen species. We showed that this zone is characterized by significant variations at a transcriptional and/or protein levels. Using low-density DNA chip technology, we evaluated the effect of a natural mixture of Aframomum angustifolium seed extract containing labdane diterpenoids on these aging markers. Expression profiles of normal human fibroblasts (NHF) were studied using a customized cDNA macroarray system containing genes covering dermal structure, inflammatory responses, and oxidative stress defense mechanisms. For normal human keratinocyte (NHK) investigations, we chose OLISA technique, a sensitive and quantitative method developed by BioMérieux specifically designed to investigate cell death, proliferation, epidermal structure, differentiation, and oxidative stress defense response. We observed that this extract strongly modified gene expression profiles of treated NHK, but weakly for NHF. This extract regulated antioxidant defenses, dermal-epidermal junction components, and epidermal renewal-related genes. Using low-density DNA chip technology, we identified new potential actions of A. angustifolium seed extract on skin aging.

Supercritical Carbon Dioxide and Microwave-Assisted Extraction of Functional Lipophilic Compounds from Arthrospira platensis

PubMed Central

Esquivel-Hernández, Diego A.; López, Víctor H.; Rodríguez-Rodríguez, José; Alemán-Nava, Gibrán S.; Cuéllar-Bermúdez, Sara P.; Rostro-Alanis, Magdalena; Parra-Saldívar, Roberto

2016-01-01

Arthrospira platensis biomass was used in order to obtain functional lipophilic compounds through green extraction technologies such as supercritical carbon dioxide fluid extraction (SFE) and microwave-assisted extraction (MAE). The temperature (T) factor was evaluated for MAE, while for SFE, pressure (P), temperature (T), and co-solvent (ethanol) (CS) were evaluated. The maximum extraction yield of the obtained oleoresin was (4.07% ± 0.14%) and (4.27% ± 0.10%) for SFE and MAE, respectively. Extracts were characterized by gas chromatography mass spectrometry (GC-MS) and gas chromatography flame ionization detector (GC-FID). The maximum contents of functional lipophilic compounds in the SFE and MAE extracts were: for carotenoids 283 ± 0.10 μg/g and 629 ± 0.13 μg/g, respectively; for tocopherols 5.01 ± 0.05 μg/g and 2.46 ± 0.09 μg/g, respectively; and for fatty acids 34.76 ± 0.08 mg/g and 15.88 ± 0.06 mg/g, respectively. In conclusion, the SFE process at P 450 bar, T 60 °C and CS 53.33% of CO2 produced the highest yield of tocopherols, carotenoids and fatty acids. The MAE process at 400 W and 50 °C gives the best extracts in terms of tocopherols and carotenoids. For yield and fatty acids, the MAE process at 400 W and 70 °C produced the highest values. Both SFE and MAE showed to be suitable green extraction technologies for obtaining functional lipophilic compounds from Arthrospira platensis. PMID:27164081

Supercritical Carbon Dioxide and Microwave-Assisted Extraction of Functional Lipophilic Compounds from Arthrospira platensis.

PubMed

Esquivel-Hernández, Diego A; López, Víctor H; Rodríguez-Rodríguez, José; Alemán-Nava, Gibrán S; Cuéllar-Bermúdez, Sara P; Rostro-Alanis, Magdalena; Parra-Saldívar, Roberto

2016-05-05

Arthrospira platensis biomass was used in order to obtain functional lipophilic compounds through green extraction technologies such as supercritical carbon dioxide fluid extraction (SFE) and microwave-assisted extraction (MAE). The temperature (T) factor was evaluated for MAE, while for SFE, pressure (P), temperature (T), and co-solvent (ethanol) (CS) were evaluated. The maximum extraction yield of the obtained oleoresin was (4.07% ± 0.14%) and (4.27% ± 0.10%) for SFE and MAE, respectively. Extracts were characterized by gas chromatography mass spectrometry (GC-MS) and gas chromatography flame ionization detector (GC-FID). The maximum contents of functional lipophilic compounds in the SFE and MAE extracts were: for carotenoids 283 ± 0.10 μg/g and 629 ± 0.13 μg/g, respectively; for tocopherols 5.01 ± 0.05 μg/g and 2.46 ± 0.09 μg/g, respectively; and for fatty acids 34.76 ± 0.08 mg/g and 15.88 ± 0.06 mg/g, respectively. In conclusion, the SFE process at P 450 bar, T 60 °C and CS 53.33% of CO₂ produced the highest yield of tocopherols, carotenoids and fatty acids. The MAE process at 400 W and 50 °C gives the best extracts in terms of tocopherols and carotenoids. For yield and fatty acids, the MAE process at 400 W and 70 °C produced the highest values. Both SFE and MAE showed to be suitable green extraction technologies for obtaining functional lipophilic compounds from Arthrospira platensis.

Publicly Open Virtualized Gaming Environment For Simulation of All Aspects Related to '100 Year Starship Study'

NASA Astrophysics Data System (ADS)

Obousy, R. K.

2012-09-01

Sending a mission to distant stars will require our civilization to develop new technologies and change the way we live. The complexity of the task is enormous [1] thus, the thought is to involve people from around the globe through the ``citizen scientist'' paradigm. The suggestion is a ``Gaming Virtual Reality Network'' (GVRN) to simulate sociological and technological aspects involved in this project. Currently there is work being done [2] in developing a technology which will construct computer games within GVRN. This technology will provide quick and easy ways for individuals to develop game scenarios related to various aspects of the ``100YSS'' project. People will be involved in solving certain tasks just by play games. Players will be able to modify conditions, add new technologies, geological conditions, social movements and assemble new strategies just by writing scenarios. The system will interface with textual and video information, extract scenarios written in millions of texts and use it to assemble new games. Thus, players will be able to simulate enormous amounts of possibilities. Information technologies will be involved which will require us to start building the system in a way that any modules can be easily replaced. Thus, GVRN should be modular and open to the community.

Geothermal energy

NASA Astrophysics Data System (ADS)

Manzella, A.

2017-07-01

Geothermal technologies use renewable energy resources to generate electricity and direct use of heat while producing very low levels of greenhouse-gas (GHG) emissions. Geothermal energy is the thermal energy stored in the underground, including any contained fluid, which is available for extraction and conversion into energy products. Electricity generation, which nowadays produces 73.7 TWh (12.7 GW of capacity) worldwide, usually requires geothermal resources temperatures of over 100 °C. For heating, geothermal resources spanning a wider range of temperatures can be used in applications such as space and district heating (and cooling, with proper technology), spa and swimming pool heating, greenhouse and soil heating, aquaculture pond heating, industrial process heating and snow melting. Produced geothermal heat in the world accounts to 164.6 TWh, with a capacity of 70.9 GW. Geothermal technology, which has focused for decades on extracting naturally heated steam or hot water from natural hydrothermal reservoirs, is developing to more advanced techniques to exploit the heat also where underground fluids are scarce and to use the Earth as a potential energy battery, by storing heat. The success of the research will enable energy recovery and utilization from a much larger fraction of the accessible thermal energy in the Earth's crust.

Advanced processing for high-bandwidth sensor systems

NASA Astrophysics Data System (ADS)

Szymanski, John J.; Blain, Phil C.; Bloch, Jeffrey J.; Brislawn, Christopher M.; Brumby, Steven P.; Cafferty, Maureen M.; Dunham, Mark E.; Frigo, Janette R.; Gokhale, Maya; Harvey, Neal R.; Kenyon, Garrett; Kim, Won-Ha; Layne, J.; Lavenier, Dominique D.; McCabe, Kevin P.; Mitchell, Melanie; Moore, Kurt R.; Perkins, Simon J.; Porter, Reid B.; Robinson, S.; Salazar, Alfonso; Theiler, James P.; Young, Aaron C.

2000-11-01

Compute performance and algorithm design are key problems of image processing and scientific computing in general. For example, imaging spectrometers are capable of producing data in hundreds of spectral bands with millions of pixels. These data sets show great promise for remote sensing applications, but require new and computationally intensive processing. The goal of the Deployable Adaptive Processing Systems (DAPS) project at Los Alamos National Laboratory is to develop advanced processing hardware and algorithms for high-bandwidth sensor applications. The project has produced electronics for processing multi- and hyper-spectral sensor data, as well as LIDAR data, while employing processing elements using a variety of technologies. The project team is currently working on reconfigurable computing technology and advanced feature extraction techniques, with an emphasis on their application to image and RF signal processing. This paper presents reconfigurable computing technology and advanced feature extraction algorithm work and their application to multi- and hyperspectral image processing. Related projects on genetic algorithms as applied to image processing will be introduced, as will the collaboration between the DAPS project and the DARPA Adaptive Computing Systems program. Further details are presented in other talks during this conference and in other conferences taking place during this symposium.

Biotechnology for Solar System Exploration

NASA Astrophysics Data System (ADS)

Steele, A.; Maule, J.; Toporski, J.; Parro-Garcia, V.; Briones, C.; Schweitzer, M.; McKay, D.

With the advent of a new era of astrobiology missions in the exploration of the solar system and the search for evidence of life elsewhere, we present a new approach to this goal, the integration of biotechnology. We have reviewed the current list of biotechnology techniques, which are applicable to miniaturization, automatization and integration into a combined flight platform. Amongst the techniques reviewed are- The uses of antibodies- Fluorescent detection strategies- Protein and DNA chip technology- Surface plasmon resonance and its relation to other techniques- Micro electronic machining (MEMS where applicable to biologicalsystems)- nanotechnology (e.g. molecular motors)- Lab-on-a-chip technology (including PCR)- Mass spectrometry (i.e. MALDI-TOF)- Fluid handling and extraction technologies- Chemical Force Microscopy (CFM)- Raman Spectroscopy We have begun to integrate this knowledge into a single flight instrument approach for the sole purpose of combining several mutually confirming tests for life, organic and/or microbial contamination, as well as prebiotic and abiotic organic chemicals. We will present several innovative designs for new instrumentation including pro- engineering design drawings of a protein chip reader for space flight and fluid handling strategies. We will also review the use of suitable extraction methodologies for use on different solar system bodies.

Design and process aspects of laboratory scale SCF particle formation systems.

PubMed

Vemavarapu, Chandra; Mollan, Matthew J; Lodaya, Mayur; Needham, Thomas E

2005-03-23

Consistent production of solid drug materials of desired particle and crystallographic morphologies under cGMP conditions is a frequent challenge to pharmaceutical researchers. Supercritical fluid (SCF) technology gained significant attention in pharmaceutical research by not only showing a promise in this regard but also accommodating the principles of green chemistry. Given that this technology attained commercialization in coffee decaffeination and in the extraction of hops and other essential oils, a majority of the off-the-shelf SCF instrumentation is designed for extraction purposes. Only a selective few vendors appear to be in the early stages of manufacturing equipment designed for particle formation. The scarcity of information on the design and process engineering of laboratory scale equipment is recognized as a significant shortcoming to the technological progress. The purpose of this article is therefore to provide the information and resources necessary for startup research involving particle formation using supercritical fluids. The various stages of particle formation by supercritical fluid processing can be broadly classified into delivery, reaction, pre-expansion, expansion and collection. The importance of each of these processes in tailoring the particle morphology is discussed in this article along with presenting various alternatives to perform these operations.

Instant controlled pressure drop technology and ultrasound assisted extraction for sequential extraction of essential oil and antioxidants.

PubMed

Allaf, Tamara; Tomao, Valérie; Ruiz, Karine; Chemat, Farid

2013-01-01

The instant controlled pressure drop (DIC) technology enabled both the extraction of essential oil and the expansion of the matrix itself which improved solvent extraction. The sequential use of DIC and Ultrasound Assisted Extraction (UAE) triggered complementary actions materialized by supplementary effects. We visualized these combination impacts by comparing them to standard techniques: Hydrodistillation (HD) and Solvent Extraction (SE). First, the extraction of orange peel Essential Oils (EO) was achieved by HD during 4h and DIC process (after optimization) during 2 min; EO yields was 1.97 mg/g dry material (dm) with HD compared to 16.57 mg/g d m with DIC. Second, the solid residue was recovered to extract antioxidant compounds (naringin and hesperidin) by SE and UAE. Scanning electron microscope showed that after HD the recovered solid shriveled as opposite to DIC treatment which expanded the product structure. HPLC analyses showed that the best kinetics and yields of naringin and hesperidin extraction was when DIC and UAE are combined. Indeed, after 1h of extraction, DIC treated orange peels with UAE were 0.825 ± 1.6 × 10(-2)g/g of dry material (dm) for hesperidin and 6.45 × 10(-2) ± 2.3 × 10(-4)g/g d m for naringin compared to 0.64 ± 2.7 × 10(-2)g/g of dry material (dm) and 5.7 × 10(-2) ± 1.6 × 10(-3)g/g d m, respectively with SE. By combining DIC to UAE, it was possible to enhance kinetics and yields of antioxidant extraction. Copyright © 2012 Elsevier B.V. All rights reserved.

Re-thinking the unimpeded tube-well growth under the depleting groundwater resources in the Punjab, Pakistan

NASA Astrophysics Data System (ADS)

Watto, Muhammad Arif; Mugera, Amin W.; Kingwell, Ross; Saqab, Muhammad Mudasar

2018-04-01

Groundwater resources are crucial in sustaining agro-ecosystems and ensuring food security in many parts of the world, including Pakistan. However, the sustainability of groundwater resources is subject to a number of challenges, including over-extraction, deterioration in quality, and vulnerability to the impacts of climate change and population growth. Given the current state of groundwater resources in Pakistan, policymakers seek to manage groundwater resources by limiting groundwater extraction. To achieve this goal on a national scale, it is important to understand the determinants of the decisions made by local farmers in respect of tube-well adoption. This study investigates smallholder farmers' decisions to adopt tube-well technology in the face of dwindling groundwater resources and falling water tables. Analysis is based on a cross-sectional survey of 200 rural households from the arid to semi-arid predominantly groundwater-irrigated plains of the Punjab province, Pakistan. It is found that farmers will adopt tube-well technology in pursuit of reliable irrigation water supplies to hedge against production risks but not against the risk associated with unfavourable extreme events (downside risk) such as total crop failure. This suggests that the adoption decision is influenced by the expected long-term rather than the short-term benefits. This paper draws attention to the need to regulate groundwater resource exploitation by requiring the use of tube-well technology to be accompanied by irrigation water-efficient techniques and technologies.

Supercritical CO2 Extraction of Rice Bran Oil -the Technology, Manufacture, and Applications.

PubMed

Sookwong, Phumon; Mahatheeranont, Sugunya

2017-06-01

Rice bran is a good source of nutrients that have large amounts of phytochemicals and antioxidants. Conventional rice bran oil production requires many processes that may deteriorate and degrade these valuable substances. Supercritical CO 2 extraction is a green alternative method for producing rice bran oil. This work reviews production of rice bran oil by supercritical carbon dioxide (SC-CO 2 ) extraction. In addition, the usefulness and advantages of SC-CO 2 extracted rice bran oil for edible oil and health purpose is also described.

Innovative technologies and social inequalities in health: A scoping review of the literature

PubMed Central

Jensen, Magnus Rom; Solhaug, Solvor; Krokstad, Steinar

2018-01-01

The aim of this study was to systematically review the range, nature, and extent of current research activity exploring the influence of innovative health-related technologies on social inequalities in health, with specific focus on a deeper understanding of the variables used to measure this connection and the pathways leading to the (re)production of inequalities. A review process was conducted, based on scoping review techniques, searching literature published from January 1, 1996 to November 25, 2016 using MEDLINE, Scopus, and ISI web of science. Search, sorting, and data extraction processes were conducted by a team of researchers and experts using a dynamic, reflexive examination process. Of 4139 studies collected from the search process, a total of 33 were included in the final analysis. Results of this study include the classification of technologies based on how these technologies are accessed and used by end users. In addition to the factors and mechanisms that influence unequal access to technologies, the results of this study highlight the importance of variations in use that importantly shape social inequalities in health. Additionally, focus on health care services technologies must be accompanied by investigating emerging technologies influencing healthy lifestyle, genomics, and personalized devices in health. Findings also suggest that choosing one measure of social position over another has important implications for the interpretation of research results. Furthermore, understanding the pathways through which various innovative health technologies reduce or (re)produce social inequalities in health is context dependent. In order to better understand social inequalities in health, these contextual variations draw attention to the need for critical distinctions between technologies based on how these various technologies are accessed and used. The results of this study provide a comprehensive starting point for future research to further investigate how innovative technologies may influence the unequal distribution of health as a human right. PMID:29614114

Innovative technologies and social inequalities in health: A scoping review of the literature.

PubMed

Weiss, Daniel; Rydland, Håvard T; Øversveen, Emil; Jensen, Magnus Rom; Solhaug, Solvor; Krokstad, Steinar

2018-01-01

The aim of this study was to systematically review the range, nature, and extent of current research activity exploring the influence of innovative health-related technologies on social inequalities in health, with specific focus on a deeper understanding of the variables used to measure this connection and the pathways leading to the (re)production of inequalities. A review process was conducted, based on scoping review techniques, searching literature published from January 1, 1996 to November 25, 2016 using MEDLINE, Scopus, and ISI web of science. Search, sorting, and data extraction processes were conducted by a team of researchers and experts using a dynamic, reflexive examination process. Of 4139 studies collected from the search process, a total of 33 were included in the final analysis. Results of this study include the classification of technologies based on how these technologies are accessed and used by end users. In addition to the factors and mechanisms that influence unequal access to technologies, the results of this study highlight the importance of variations in use that importantly shape social inequalities in health. Additionally, focus on health care services technologies must be accompanied by investigating emerging technologies influencing healthy lifestyle, genomics, and personalized devices in health. Findings also suggest that choosing one measure of social position over another has important implications for the interpretation of research results. Furthermore, understanding the pathways through which various innovative health technologies reduce or (re)produce social inequalities in health is context dependent. In order to better understand social inequalities in health, these contextual variations draw attention to the need for critical distinctions between technologies based on how these various technologies are accessed and used. The results of this study provide a comprehensive starting point for future research to further investigate how innovative technologies may influence the unequal distribution of health as a human right.

[Studies on technology optimization for extracting triterpenoid saponins from Picria felterrae by multi-target grading method].

PubMed

Fang, Hong; Ning, De-sheng; Liang, Xiao-yan

2009-12-01

To study the optimum extraction conditions of triterpenoid saponins from Picria felterrae. The optimum extraction conditions were investigated by the contents of the total glycosides and picfeltarraenine I A and I B, using orthogonal test. The optimum extraction conditions were as follows: using 70% alcohol of 19 times than the amount of original material soaking 3 hours, extracting twice with hot reflux method at 80 degrees C, 3h the first time, 1 h the second time. The selected extraction conditions are convenient and practical with high accuracy, and could be used as a reference for industrial production.

Image Analysis and Modeling

DTIC Science & Technology

1975-08-01

image analysis and processing tasks such as information extraction, image enhancement and restoration, coding, etc. The ultimate objective of this research is to form a basis for the development of technology relevant to military applications of machine extraction of information from aircraft and satellite imagery of the earth’s surface. This report discusses research activities during the three month period February 1 - April 30,

CPU and GPU-based Numerical Simulations of Combustion Processes

DTIC Science & Technology

2012-04-27

Distribution unlimited UCLA MAE Research and Technology Review April 27, 2012 Magnetohydrodynamic Augmentation of the Pulse Detonation Rocket Engines...Pulse Detonation Rocket-Induced MHD Ejector (PDRIME) – Energy extract from exhaust flow by MHD generator – Seeded air stream acceleration by MHD...accelerator for thrust enhancement and control • Alternative concept: Magnetic piston – During PDE blowdown process, MHD extracts energy and

A Spectroscopic study on the fuel value of softwoods in relation to chemical composition

Treesearch

Chi-Leung So; Thomas L. Eberhardt; Les Groom; Todd F. Shupe

2012-01-01

The recent focus on bioenergy has led to interest in developing alternative technologies for assessing the fuel value of available biomass resources. In this study, both near- and mid-infrared spectroscopic datawere used to predict fuel value in relation to extractives and lignin contents for longleaf pine wood. Samples were analyzed both before and after extraction....

A novel approach to the simultaneous extraction and non-targeted analysis of the small molecules metabolome and lipidome using 96-well solid phase extraction plates with column-switching technology.

PubMed

Li, Yubo; Zhang, Zhenzhu; Liu, Xinyu; Li, Aizhu; Hou, Zhiguo; Wang, Yuming; Zhang, Yanjun

2015-08-28

This study combines solid phase extraction (SPE) using 96-well plates with column-switching technology to construct a rapid and high-throughput method for the simultaneous extraction and non-targeted analysis of small molecules metabolome and lipidome based on ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry. This study first investigated the columns and analytical conditions for small molecules metabolome and lipidome, separated by an HSS T3 and BEH C18 columns, respectively. Next, the loading capacity and actuation duration of SPE were further optimized. Subsequently, SPE and column switching were used together to rapidly and comprehensively analyze the biological samples. The experimental results showed that the new analytical procedure had good precision and maintained sample stability (RSD<15%). The method was then satisfactorily applied to more widely analyze the small molecules metabolome and lipidome to test the throughput. The resulting method represents a new analytical approach for biological samples, and a highly useful tool for researches in metabolomics and lipidomics. Copyright © 2015 Elsevier B.V. All rights reserved.

Rapid DNA extraction from dried blood spots on filter paper: potential applications in biobanking.

PubMed

Choi, Eun-Hye; Lee, Sang Kwang; Ihm, Chunhwa; Sohn, Young-Hak

2014-12-01

Dried blood spot (DBS) technology is a microsampling alternative to traditional plasma or serum sampling for pharmaco- or toxicokinetic evaluation. DBS technology has been applied to diagnostic screening in drug discovery, nonclinical, and clinical settings. We have developed an improved elution protocol involving boiling of blood spots dried on Whatman filter paper. The purpose of this study was to compare the quality, purity, and quantity of DNA isolated from frozen blood samples and DBSs. We optimized a method for extraction and estimation of DNA from blood spots dried on filter paper (3-mm FTA card). A single DBS containing 40 μL blood was used. DNA was efficiently extracted in phosphate-buffered saline (PBS) or Tris-EDTA (TE) buffer by incubation at 37°C overnight. DNA was stable in DBSs that were stored at room temperature or frozen. The housekeeping genes GAPDH and beta-actin were used as positive standards for polymerase chain reaction (PCR) validation of general diagnostic screening. Our simple and convenient DBS storage and extraction methods are suitable for diagnostic screening by using very small volumes of blood collected on filter paper, and can be used in biobanks for blood sample storage.

[Recent advance in solidification/stabilization technology for the remediation of heavy metals-contaminated soil].

PubMed

Hao, Han-zhou; Chen, Tong-bin; Jin, Meng-gui; Lei, Mei; Liu, Cheng-wu; Zu, Wen-pu; Huang, Li-mi

2011-03-01

Remediation of heavy metals-contaminated soil is still a difficulty and a hotspot of international research projects. At present, the technologies commonly adopted for the remediation of contaminated sites mainly include excavation, solidification/stabilization (S/S), soil washing, soil vapor extraction (SVE), thermal treatment, and bioremediation. Based on the S/S technical guidelines of Unite State Environmental Protection Agency (EPA) and United Kingdom Environment Agency (EA) and the domestic and foreign patents, this paper introduced the concepts of S/S and its development status at home and abroad, and discussed its future development directions. Solidification refers to a process that binds contaminated media with a reagent, changing the media's physical properties via increasing its compressive strength, decreasing its permeability, and encapsulating the contaminants to form a solid material. Stabilization refers to the process that involves a chemical reaction which reduces the leachability of a waste, chemically immobilizes the waste and reduces its solubility, making the waste become less harmful or less mobile. S/S technology includes cement solidification, lime pozzolanic solidification, plastic materials stabilization, vitrification, and regent-based stabilization. Stabilization (or immobilization) treatment processes convert contaminants to less mobile forms through chemical or thermal interactions. In stabilization technology, the aim of adding agents is to change the soil physical and chemical properties through pH control technology, redox potential technology, precipitation techniques, adsorption technology, and ion-exchange technology that change the existing forms of heavy metals in soil, and thus, reduce the heavy metals bioavailability and mobility. This review also discussed the S/S evaluation methods, highlighted the need to enhance S/S technology in the molecular bonding, soil polymers, and formulation of China's S/S technical guidelines.

Grist : grid-based data mining for astronomy

NASA Technical Reports Server (NTRS)

Jacob, Joseph C.; Katz, Daniel S.; Miller, Craig D.; Walia, Harshpreet; Williams, Roy; Djorgovski, S. George; Graham, Matthew J.; Mahabal, Ashish; Babu, Jogesh; Berk, Daniel E. Vanden;

Application of ionic liquid in liquid phase microextraction technology.

PubMed

Han, Dandan; Tang, Baokun; Lee, Yu Ri; Row, Kyung Ho

2012-11-01

Ionic liquids (ILs) are novel nonmolecular solvents. Their unique properties, such as high thermal stability, tunable viscosity, negligible vapor pressure, nonflammability, and good solubility for inorganic and organic compounds, make them excellent candidates as extraction media for a range of microextraction techniques. Many physical properties of ILs can be varied, and the structural design can be tuned to impart the desired functionality and enhance the analyte extraction selectivity, efficiency, and sensitivity. This paper provides an overview of the applications of ILs in liquid phase microextraction technology, such as single-drop microextraction, hollow fiber based liquid phase microextraction, and dispersive liquid-liquid microextraction. The sensitivity, linear calibration range, and detection limits for a range of target analytes in the methods were analyzed to determine the advantages of ILs in liquid phase microextraction. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Extended performance technology study 30-cm thruster

NASA Technical Reports Server (NTRS)

Beattie, J. R.

1983-01-01

The extended performance technology study was an investigation of advanced discharge chambers and thruster components that were designed to operate under conditions which result in an increase in the thrust and thrust to power ratio of the state of the art J-series thruster. The high level of performance was achieved by a discharge chamber that employs a ring cusp magnetic confinement arrangement and a three grid ion extraction assembly. It is shown that the ring cusp magnetic field geometry confines the plasma to the volume immediately adjacent to the ion extraction assembly. A high emission current hollow cathode that demonstrated operation at an emission current as high as J sub E = 40 A, and measurements which show the breakdown voltage of individual sections of the J-series propellant flow electrical isolator is about 340 V per section are investigated.

Grist: Grid-based Data Mining for Astronomy

NASA Astrophysics Data System (ADS)

Jacob, J. C.; Katz, D. S.; Miller, C. D.; Walia, H.; Williams, R. D.; Djorgovski, S. G.; Graham, M. J.; Mahabal, A. A.; Babu, G. J.; vanden Berk, D. E.; Nichol, R.

2005-12-01

The Grist project is developing a grid-technology based system as a research environment for astronomy with massive and complex datasets. This knowledge extraction system will consist of a library of distributed grid services controlled by a workflow system, compliant with standards emerging from the grid computing, web services, and virtual observatory communities. This new technology is being used to find high redshift quasars, study peculiar variable objects, search for transients in real time, and fit SDSS QSO spectra to measure black hole masses. Grist services are also a component of the ``hyperatlas'' project to serve high-resolution multi-wavelength imagery over the Internet. In support of these science and outreach objectives, the Grist framework will provide the enabling fabric to tie together distributed grid services in the areas of data access, federation, mining, subsetting, source extraction, image mosaicking, statistics, and visualization.

Hybrid Technology of Hard Coal Mining from Seams Located at Great Depths

NASA Astrophysics Data System (ADS)

Czaja, Piotr; Kamiński, Paweł; Klich, Jerzy; Tajduś, Antoni

2014-10-01

Learning to control fire changed the life of man considerably. Learning to convert the energy derived from combustion of coal or hydrocarbons into another type of energy, such as steam pressure or electricity, has put him on the path of scientific and technological revolution, stimulating dynamic development. Since the dawn of time, fossil fuels have been serving as the mankind's natural reservoir of energy in an increasingly great capacity. A completely incomprehensible refusal to use fossil fuels causes some local populations, who do not possess a comprehensive knowledge of the subject, to protest and even generate social conflicts as an expression of their dislike for the extraction of minerals. Our times are marked by the search for more efficient ways of utilizing fossil fuels by introducing non-conventional technologies of exploiting conventional energy sources. During apartheid, South Africa demonstrated that cheap coal can easily satisfy total demand for liquid and gaseous fuels. In consideration of current high prices of hydrocarbon media (oil and gas), gasification or liquefaction of coal seems to be the innovative technology convergent with contemporary expectations of both energy producers as well as environmentalists. Known mainly from literature reports, underground coal gasification technologies can be brought down to two basic methods: - shaftless method - drilling, in which the gasified seam is uncovered using boreholes drilled from the surface, - shaft method, in which the existing infrastructure of underground mines is used to uncover the seams. This paper presents a hybrid shaft-drilling approach to the acquisition of primary energy carriers (methane and syngas) from coal seams located at great depths. A major advantage of this method is the fact that the use of conventional coal mining technology requires the seams located at great depths to be placed on the off-balance sheet, while the hybrid method of underground gasification enables them to become a source of additional energy for the economy. It should be noted, however, that the shaft-drilling method cannot be considered as an alternative to conventional methods of coal extraction, but rather as a complementary and cheaper way of utilizing resources located almost beyond the technical capabilities of conventional extraction methods due to the associated natural hazards and high costs of combating them. This article presents a completely different approach to the issue of underground coal gasification. Repurposing of the already fully depreciated mining infrastructure for the gasification process may result in a large value added of synthesis gas production and very positive economic effect.

NASA In-Situ Resource Utilization (ISRU) Technology and Development Project Overview

NASA Technical Reports Server (NTRS)

Sanders, Gerald B.; Lason, William E.; Sacksteder, Kurt R.; Mclemore, Carole; Johnson, Kenneth

2008-01-01

Since the Vision for Space Exploration (VSE) was released in 2004, NASA, in conjunction with international space agencies, industry, and academia, has continued to define and refine plans for sustained and affordable robotic and human exploration of the Moon and beyond. With the goal of establishing a lunar Outpost on the Moon to extend human presence, pursue scientific activities, use the Moon to prepare for future human missions to Mars, and expand Earth s economic sphere, a change in how space exploration is performed is required. One area that opens up the possibility for the first time of breaking our reliance on Earth supplied consumables and learn to live off the land is In-Situ Resource Utilization (ISRU). ISRU, which involves the extraction and processing of space resources into useful products, can have a substantial impact on mission and architecture concepts. In particular, the ability to make propellants, life support consumables, and fuel cell reagents can significantly reduce the cost, mass, and risk of sustained human activities beyond Earth. However, ISRU is an unproven capability for human lunar exploration and can not be put in the critical path of lunar Outpost success until it has been proven. Therefore, ISRU development and deployment needs to take incremental steps toward the desired end state. To ensure ISRU capabilities are available for pre-Outpost and Outpost deployment by 2020, and mission and architecture planners are confident that ISRU can meet initial and long term mission requirements, the ISRU Project is developing technologies and systems in three critical areas: (1) Regolith Excavation, Handling and Material Transportation; (2) Oxygen Extraction from Regolith; and (3) Volatile Extraction and Resource Prospecting, and in four development stages: (I) Demonstrate feasibility; (II) Evolve system w/ improved technologies; (III) Develop one or more systems to TRL 6 before start of flight development; and (IV) Flight development for Outpost. To minimize cost and ensure that ISRU technologies, systems, and functions are integrated properly into the Outpost, technology development efforts are being coordinated with other development areas such as Surface Mobility, Surface Power, Life Support, EVA, and Propulsion. Lastly, laboratory and field system-level tests and demonstrations will be performed as often as possible to demonstrate improvements in: Capabilities (ex. digging deeper); Performance (ex. lower power); and Duration (ex. more autonomy or more robustness). This presentation will provide the status of work performed to date within the NASA ISRU project with respect to technology and system development and field demonstration activities, as well as the current strategy to implement ISRU in future robotic and human lunar exploration missions.

A fast and efficient method for device level layout analysis

NASA Astrophysics Data System (ADS)

Dong, YaoQi; Zou, Elaine; Pang, Jenny; Huang, Lucas; Yang, Legender; Zhang, Chunlei; Du, Chunshan; Hu, Xinyi; Wan, Qijian

2017-03-01

There is an increasing demand for device level layout analysis, especially as technology advances. The analysis is to study standard cells by extracting and classifying critical dimension parameters. There are couples of parameters to extract, like channel width, length, gate to active distance, and active to adjacent active distance, etc. for 14nm technology, there are some other parameters that are cared about. On the one hand, these parameters are very important for studying standard cell structures and spice model development with the goal of improving standard cell manufacturing yield and optimizing circuit performance; on the other hand, a full chip device statistics analysis can provide useful information to diagnose the yield issue. Device analysis is essential for standard cell customization and enhancements and manufacturability failure diagnosis. Traditional parasitic parameters extraction tool like Calibre xRC is powerful but it is not sufficient for this device level layout analysis application as engineers would like to review, classify and filter out the data more easily. This paper presents a fast and efficient method based on Calibre equation-based DRC (eqDRC). Equation-based DRC extends the traditional DRC technology to provide a flexible programmable modeling engine which allows the end user to define grouped multi-dimensional feature measurements using flexible mathematical expressions. This paper demonstrates how such an engine and its programming language can be used to implement critical device parameter extraction. The device parameters are extracted and stored in a DFM database which can be processed by Calibre YieldServer. YieldServer is data processing software that lets engineers query, manipulate, modify, and create data in a DFM database. These parameters, known as properties in eqDRC language, can be annotated back to the layout for easily review. Calibre DesignRev can create a HTML formatted report of the results displayed in Calibre RVE which makes it easy to share results among groups. This method has been proven and used in SMIC PDE team and SPICE team.

Scaling up Dietary Data for Decision-Making in Low-Income Countries: New Technological Frontiers.

PubMed

Bell, Winnie; Colaiezzi, Brooke A; Prata, Cathleen S; Coates, Jennifer C

2017-11-01

Dietary surveys in low-income countries (LICs) are hindered by low investment in the necessary research infrastructure, including a lack of basic technology for data collection, links to food composition information, and data processing. The result has been a dearth of dietary data in many LICs because of the high cost and time burden associated with dietary surveys, which are typically carried out by interviewers using pencil and paper. This study reviewed innovative dietary assessment technologies and gauged their suitability to improve the quality and time required to collect dietary data in LICs. Predefined search terms were used to identify technologies from peer-reviewed and gray literature. A total of 78 technologies were identified and grouped into 6 categories: 1 ) computer- and tablet-based, 2 ) mobile-based, 3 ) camera-enabled, 4 ) scale-based, 5 ) wearable, and 6 ) handheld spectrometers. For each technology, information was extracted on a number of overarching factors, including the primary purpose, mode of administration, and data processing capabilities. Each technology was then assessed against predetermined criteria, including requirements for respondent literacy, battery life, requirements for connectivity, ability to measure macro- and micronutrients, and overall appropriateness for use in LICs. Few technologies reviewed met all the criteria, exhibiting both practical constraints and a lack of demonstrated feasibility for use in LICs, particularly for large-scale, population-based surveys. To increase collection of dietary data in LICs, development of a contextually adaptable, interviewer-administered dietary assessment platform is recommended. Additional investments in the research infrastructure are equally important to ensure time and cost savings for the user.

Scaling up Dietary Data for Decision-Making in Low-Income Countries: New Technological Frontiers

PubMed Central

Bell, Winnie; Colaiezzi, Brooke A; Prata, Cathleen S

2017-01-01

Dietary surveys in low-income countries (LICs) are hindered by low investment in the necessary research infrastructure, including a lack of basic technology for data collection, links to food composition information, and data processing. The result has been a dearth of dietary data in many LICs because of the high cost and time burden associated with dietary surveys, which are typically carried out by interviewers using pencil and paper. This study reviewed innovative dietary assessment technologies and gauged their suitability to improve the quality and time required to collect dietary data in LICs. Predefined search terms were used to identify technologies from peer-reviewed and gray literature. A total of 78 technologies were identified and grouped into 6 categories: 1) computer- and tablet-based, 2) mobile-based, 3) camera-enabled, 4) scale-based, 5) wearable, and 6) handheld spectrometers. For each technology, information was extracted on a number of overarching factors, including the primary purpose, mode of administration, and data processing capabilities. Each technology was then assessed against predetermined criteria, including requirements for respondent literacy, battery life, requirements for connectivity, ability to measure macro- and micronutrients, and overall appropriateness for use in LICs. Few technologies reviewed met all the criteria, exhibiting both practical constraints and a lack of demonstrated feasibility for use in LICs, particularly for large-scale, population-based surveys. To increase collection of dietary data in LICs, development of a contextually adaptable, interviewer-administered dietary assessment platform is recommended. Additional investments in the research infrastructure are equally important to ensure time and cost savings for the user. PMID:29141974

Privacy Attitudes among Early Adopters of Emerging Health Technologies.

PubMed

Cheung, Cynthia; Bietz, Matthew J; Patrick, Kevin; Bloss, Cinnamon S

2016-01-01

Advances in health technology such as genome sequencing and wearable sensors now allow for the collection of highly granular personal health data from individuals. It is unclear how people think about privacy in the context of these emerging health technologies. An open question is whether early adopters of these advances conceptualize privacy in different ways than non-early adopters. This study sought to understand privacy attitudes of early adopters of emerging health technologies. Transcripts from in-depth, semi-structured interviews with early adopters of genome sequencing and health devices and apps were analyzed with a focus on participant attitudes and perceptions of privacy. Themes were extracted using inductive content analysis. Although interviewees were willing to share personal data to support scientific advancements, they still expressed concerns, as well as uncertainty about who has access to their data, and for what purpose. In short, they were not dismissive of privacy risks. Key privacy-related findings are organized into four themes as follows: first, personal data privacy; second, control over personal information; third, concerns about discrimination; and fourth, contributing personal data to science. Early adopters of emerging health technologies appear to have more complex and nuanced conceptions of privacy than might be expected based on their adoption of personal health technologies and participation in open science. Early adopters also voiced uncertainty about the privacy implications of their decisions to use new technologies and share their data for research. Though not representative of the general public, studies of early adopters can provide important insights into evolving attitudes toward privacy in the context of emerging health technologies and personal health data research.

High-efficient extraction of principal medicinal components from fresh Phellodendron bark (cortex phellodendri).

PubMed

Xu, Keqin; He, Gongxiu; Qin, Jieming; Cheng, Xuexiang; He, Hanjie; Zhang, Dangquan; Peng, Wanxi

2018-05-01

There are three key medicinal components (phellodendrine, berberine and palmatine) in the extracts of Phellodendron bark, as one of the fundamental herbs of traditional Chinese medicine. Different extraction methods and solvent combinations were investigated to obtain the optimal technologies for high-efficient extraction of these medicinal components. The results showed that combined solvents have higher extracting effect of phellodendrine, berberine and palmatine than single solvent, and the effect of ultrasonic extraction is distinctly better than those of distillation and soxhlet extraction. The hydrochloric acid/methanol-ultrasonic extraction has the best effect for three medicinal components of fresh Phellodendron bark, providing an extraction yield of 103.12 mg/g berberine, 24.41 mg/g phellodendrine, 1.25 mg/g palmatine.

Colorimetric Solid Phase Extraction (CSPE): Using Color to Monitor Spacecraft Water Quality

NASA Technical Reports Server (NTRS)

Gazda, Daniel B.; Nolan, Daniel J.; Rutz, Jeffrey A.; Schultz, John R.; Siperko, Lorraine M.; Porter, Marc D.; Lipert, Robert J.; Flint, Stephanie M.; McCoy, J. Torin

2010-01-01

In August 2009, an experimental water quality monitoring kit based on Colorimetric Solid Phase Extraction (CSPE) technology was delivered to the International Space Station (ISS). The kit, called the Colorimetric Water Quality Monitoring Kit (CWQMK), was launched as a Station Development Test Objective (SDTO) experiment to evaluate the suitability of CSPE technology for routine use monitoring water quality on the ISS. CSPE is a sorption-spectrophotometric technique that combines colorimetric reagents, solid-phase extraction, and diffuse reflectance spectroscopy to quantify trace analytes in water samples. In CSPE, a known volume of sample is metered through a membrane disk that has been impregnated with an analyte-specific colorimetric reagent and any additives required to optimize the formation of the analyte-reagent complex. As the sample flows through the membrane disk, the target analyte is selectively extracted, concentrated, and complexed. Formation of the analyte-reagent complex causes a detectable change in the color of the membrane disk that is proportional to the amount of analyte present in the sample. The analyte is then quantified by measuring the color of the membrane disk surface using a hand-held diffuse reflectance spectrophotometer (DRS). The CWQMK provides the capability to measure the ionic silver (Ag +) and molecular iodine (I2) in water samples on-orbit. These analytes were selected for the evaluation of CSPE technology because they are the biocides used in the potable water storage and distribution systems on the ISS. Biocides are added to the potable water systems on spacecraft to inhibit microbial growth. On the United States (US) segment of the ISS molecular iodine serves as the biocide, while the Russian space agency utilizes silver as a biocide in their systems. In both cases, the biocides must be maintained at a level sufficient to control bacterial growth, but low enough to avoid any negative effects on crew health. For example, the presence of high levels of iodine in water can cause taste and odor issues that result in decreased water consumption by the crew. There are also concerns about potential impacts on thyroid function following exposure to high levels of iodine. With silver, there is a risk of developing argyria, an irreversible blue-gray discoloration of the skin, associated with long term consumption of water containing high concentrations of silver. The need to ensure that safe, effective levels of biocide are maintained in the potable water systems on the ISS provides a perfect platform for evaluating the suitability of CSPE technology for in-flight water quality monitoring. This paper provides an overview of CSPE technology and details on the silver and iodine methods used in the CWQMK. It also reports results obtained during in-flight analyses performed with the CWQMK and briefly discusses other potential applications for CSPE technology in both the spacecraft and terrestrial environments.

Large-screen display technology assessment for military applications

NASA Astrophysics Data System (ADS)

Blaha, Richard J.

1990-08-01

Full-color, large screen display systems can enhance military applications that require group presentation, coordinated decisions, or interaction between decision makers. The technology already plays an important role in operations centers, simulation facilities, conference rooms, and training centers. Some applications display situational, status, or briefing information, while others portray instructional material for procedural training or depict realistic panoramic scenes that are used in simulators. While each specific application requires unique values of luminance, resolution, response time, reliability, and the video interface, suitable performance can be achieved with available commercial large screen displays. Advances in the technology of large screen displays are driven by the commercial applications because the military applications do not provide the significant market share enjoyed by high definition television (HDTV), entertainment, advertisement, training, and industrial applications. This paper reviews the status of full-color, large screen display technologies and includes the performance and cost metrics of available systems. For this discussion, performance data is based upon either measurements made by our personnel or extractions from vendors' data sheets.

Acoustic technology for high-performance disruption and extraction of plant proteins.

PubMed

Toorchi, Mahmoud; Nouri, Mohammad-Zaman; Tsumura, Makoto; Komatsu, Setsuko

2008-07-01

Acoustic technology shows the capability of protein pellet homogenization from different tissue samples of soybean and rice in a manner comparable to the ordinary mortar/pestle method and far better than the vortex/ultrasonic method with respect to the resolution of the protein pattern through two-dimensional polyacrylamide gel electrophoresis (2D-PAGE). With acoustic technology, noncontact tissue disruption and protein pellet homogenization can be carried out in a computer-controlled manner, which ultimately increases the efficiency of the process for a large number of samples. A lysis buffer termed the T-buffer containing TBP, thiourea, and CHAPS yields an excellent result for the 2D-PAGE separation of soybean plasma membrane proteins followed by the 2D-PAGE separation of crude protein of soybean and rice tissues. For this technology, the T-buffer is preferred because protein quantification is possible by eliminating the interfering compound 2-mercaptoethanol and because of the high reproducibility of 2D-PAGE separation.

Quantifying Traces of Tool Use: A Novel Morphometric Analysis of Damage Patterns on Percussive Tools

PubMed Central

Caruana, Matthew V.; Carvalho, Susana; Braun, David R.; Presnyakova, Darya; Haslam, Michael; Archer, Will; Bobe, Rene; Harris, John W. K.

2014-01-01

Percussive technology continues to play an increasingly important role in understanding the evolution of tool use. Comparing the archaeological record with extractive foraging behaviors in nonhuman primates has focused on percussive implements as a key to investigating the origins of lithic technology. Despite this, archaeological approaches towards percussive tools have been obscured by a lack of standardized methodologies. Central to this issue have been the use of qualitative, non-diagnostic techniques to identify percussive tools from archaeological contexts. Here we describe a new morphometric method for distinguishing anthropogenically-generated damage patterns on percussive tools from naturally damaged river cobbles. We employ a geomatic approach through the use of three-dimensional scanning and geographical information systems software to statistically quantify the identification process in percussive technology research. This will strengthen current technological analyses of percussive tools in archaeological frameworks and open new avenues for translating behavioral inferences of early hominins from percussive damage patterns. PMID:25415303

Modern supercritical fluid technology for food applications.

PubMed

King, Jerry W

2014-01-01

This review provides an update on the use of supercritical fluid (SCF) technology as applied to food-based materials. It advocates the use of the solubility parameter theory (SPT) for rationalizing the results obtained when employing sub- and supercritical media to food and nutrient-bearing materials and for optimizing processing conditions. Total extraction and fractionation of foodstuffs employing SCFs are compared and are illustrated by using multiple fluids and unit processes to obtain the desired food product. Some of the additional prophylactic benefits of using carbon dioxide as the processing fluid are explained and illustrated with multiple examples of commercial products produced using SCF media. I emphasize the role of SCF technology in the context of environmentally benign and sustainable processing, as well as its integration into an overall biorefinery concept. Conclusions are drawn in terms of current trends in the field and future research that is needed to secure new applications of the SCF platform as applied in food science and technology.

Fundamentals of converging mining technologies in integrated development of mineral resources of lithosphere

NASA Astrophysics Data System (ADS)

Trubetskoy, KN; Galchenko, YuP; Eremenko, VA

2018-03-01

The paper sets forth a theoretical framework for the strategy of the radically new stage in development of geotechnologies under conditions of rapidly aggravating environmental crisis of the contemporary technocratic civilization that utilizes the substance extracted from the lithosphere as the source of energy and materials. The authors of the paper see the opportunity to overcome the conflict between the techno- and bio-spheres in the area of mineral raw materials by means of changing the technological paradigm of integrated mineral development by implementing nature-like technologies oriented to the ideas and methods of converging resources of natural biota as the object of the environmental protection and geotechnologies as the major source of ecological hazards induced in the course of development of mineral resources of lithosphere.

Investigation of an artificial intelligence technology--Model trees. Novel applications for an immediate release tablet formulation database.

PubMed

Shao, Q; Rowe, R C; York, P

2007-06-01

This study has investigated an artificial intelligence technology - model trees - as a modelling tool applied to an immediate release tablet formulation database. The modelling performance was compared with artificial neural networks that have been well established and widely applied in the pharmaceutical product formulation fields. The predictability of generated models was validated on unseen data and judged by correlation coefficient R(2). Output from the model tree analyses produced multivariate linear equations which predicted tablet tensile strength, disintegration time, and drug dissolution profiles of similar quality to neural network models. However, additional and valuable knowledge hidden in the formulation database was extracted from these equations. It is concluded that, as a transparent technology, model trees are useful tools to formulators.

Automated site characterization for robotic sample acquisition systems

NASA Astrophysics Data System (ADS)

Scholl, Marija S.; Eberlein, Susan J.

1993-04-01

A mobile, semiautonomous vehicle with multiple sensors and on-board intelligence is proposed for performing preliminary scientific investigations on extraterrestrial bodies prior to human exploration. Two technologies, a hybrid optical-digital computer system based on optical correlator technology and an image and instrument data analysis system, provide complementary capabilities that might be part of an instrument package for an intelligent robotic vehicle. The hybrid digital-optical vision system could perform real-time image classification tasks using an optical correlator with programmable matched filters under control of a digital microcomputer. The data analysis system would analyze visible and multiband imagery to extract mineral composition and textural information for geologic characterization. Together these technologies would support the site characterization needs of a robotic vehicle for both navigational and scientific purposes.

Definition of information technology architectures for continuous data management and medical device integration in diabetes.

PubMed

Hernando, M Elena; Pascual, Mario; Salvador, Carlos H; García-Sáez, Gema; Rodríguez-Herrero, Agustín; Martínez-Sarriegui, Iñaki; Gómez, Enrique J

2008-09-01

The growing availability of continuous data from medical devices in diabetes management makes it crucial to define novel information technology architectures for efficient data storage, data transmission, and data visualization. The new paradigm of care demands the sharing of information in interoperable systems as the only way to support patient care in a continuum of care scenario. The technological platforms should support all the services required by the actors involved in the care process, located in different scenarios and managing diverse information for different purposes. This article presents basic criteria for defining flexible and adaptive architectures that are capable of interoperating with external systems, and integrating medical devices and decision support tools to extract all the relevant knowledge to support diabetes care.

State of the Art, Trends and Future of Bluetooth Low Energy, Near Field Communication and Visible Light Communication in the Development of Smart Cities.

PubMed

Cerruela García, Gonzalo; Luque Ruiz, Irene; Gómez-Nieto, Miguel Ángel

2016-11-23

The current social impact of new technologies has produced major changes in all areas of society, creating the concept of a smart city supported by an electronic infrastructure, telecommunications and information technology. This paper presents a review of Bluetooth Low Energy (BLE), Near Field Communication (NFC) and Visible Light Communication (VLC) and their use and influence within different areas of the development of the smart city. The document also presents a review of Big Data Solutions for the management of information and the extraction of knowledge in an environment where things are connected by an "Internet of Things" (IoT) network. Lastly, we present how these technologies can be combined together to benefit the development of the smart city.

Patent information retrieval: approaching a method and analysing nanotechnology patent collaborations.

PubMed

Ozcan, Sercan; Islam, Nazrul

2017-01-01

Many challenges still remain in the processing of explicit technological knowledge documents such as patents. Given the limitations and drawbacks of the existing approaches, this research sets out to develop an improved method for searching patent databases and extracting patent information to increase the efficiency and reliability of nanotechnology patent information retrieval process and to empirically analyse patent collaboration. A tech-mining method was applied and the subsequent analysis was performed using Thomson data analyser software. The findings show that nations such as Korea and Japan are highly collaborative in sharing technological knowledge across academic and corporate organisations within their national boundaries, and China presents, in some cases, a great illustration of effective patent collaboration and co-inventorship. This study also analyses key patent strengths by country, organisation and technology.

Valorisation of softwood bark through extraction of utilizable chemicals. A review.

PubMed

Jablonsky, M; Nosalova, J; Sladkova, A; Haz, A; Kreps, F; Valka, J; Miertus, S; Frecer, V; Ondrejovic, M; Sima, J; Surina, I

2017-11-01

Softwood bark is an important source for producing chemicals and materials as well as bioenergy. Extraction is regarded as a key technology for obtaining chemicals in general, and valorizing bark as a source of such chemicals in particular. In this paper, properties of 237 compounds identified in various studies dealing with extraction of softwood bark were described. Finally, some challenges and perspectives on the production of chemicals from bark are discussed. Copyright © 2017 Elsevier Inc. All rights reserved.

Development of an improved sample preparation platform for acidic endogenous hormones in plant tissues using electromembrane extraction.

PubMed

Suh, Joon Hyuk; Han, Sang Beom; Wang, Yu

2018-02-02

Despite their importance in pivotal signaling pathways due to trace quantities and complex matrices, the analysis of plant hormones is a challenge. Here, to improve this issue, we present an electromembrane extraction technology combined with liquid chromatography-tandem mass spectrometry for determination of acidic plant hormones including jasmonic acid, abscisic acid, salicylic acid, benzoic acid, gibberellic acid and gibberellin A 4 in plant tissues. Factors influencing extraction efficiency, such as voltage, extraction time and stirring rate were optimized using a design of experiments. Analytical performance was evaluated in terms of specificity, linearity, limit of quantification, precision, accuracy, recovery and repeatability. The results showed good linearity (r 2  > 0.995), precision and acceptable accuracy. The limit of quantification ranged from 0.1 to 10 ng mL -1 , and the recoveries were 34.6-50.3%. The developed method was applied in citrus leaf samples, showing better clean-up efficiency, as well as higher sensitivity compared to a previous method using liquid-liquid extraction. Organic solvent consumption was minimized during the process, making it an appealing method. More noteworthy, electromembrane extraction has been scarcely applied to plant tissues, and this is the first time that major plant hormones were extracted using this technology, with high sensitivity and selectivity. Taken together, this work gives not only a novel sample preparation platform using an electric field for plant hormones, but also a good example of extracting complex plant tissues in a simple and effective way. Copyright © 2017 Elsevier B.V. All rights reserved.

Proceedings of the Lunar Materials Technology Symposium

NASA Technical Reports Server (NTRS)

1992-01-01

The meeting was organized around a possible lunar outpost scenario, featuring industrial technologies, systems, and components applicable to the extraction, processing, and fabrication of local materials. Acknowledged space resources experts as well as investigators from outside the field whose knowledge could be applied to space development activities were brought together. Presentations came from a variety of specialists in fields such as minerals processing, environmental control, and communications. The sessions of the symposium were divided into the following areas: resource characterization, energy management, materials processing, environment control, and automation and communications.

Present status and trends of image fusion

NASA Astrophysics Data System (ADS)

Xiang, Dachao; Fu, Sheng; Cai, Yiheng

2009-10-01

Image fusion information extracted from multiple images which is more accurate and reliable than that from just a single image. Since various images contain different information aspects of the measured parts, and comprehensive information can be obtained by integrating them together. Image fusion is a main branch of the application of data fusion technology. At present, it was widely used in computer vision technology, remote sensing, robot vision, medical image processing and military field. This paper mainly presents image fusion's contents, research methods, and the status quo at home and abroad, and analyzes the development trend.

Walk-through survey report: control technology for fermentation processes at Wyeth Laboratories, Inc. , West Chester, Pennsylvania

DOE Office of Scientific and Technical Information (OSTI.GOV)

Martinez, K.F.

A walk-through survey was conducted at Wyeth Laboratories, Incorporated, West Chester, Pennsylvania in November, 1983. The purpose of the survey was to evaluate the control technology for the fermentation processes. The facility produced penicillin-V and penicillin-G using the microbial strain Penicillium-chrysogenum. Medical examinations were available for fermentation and extraction process workers. Safety shoes and glasses and disposable dust respirators were provided. The author concludes that Wyeth has in operation an apparently effective system of control measures.

Gait recognition based on integral outline

NASA Astrophysics Data System (ADS)

Ming, Guan; Fang, Lv

2017-02-01

Biometric identification technology replaces traditional security technology, which has become a trend, and gait recognition also has become a hot spot of research because its feature is difficult to imitate and theft. This paper presents a gait recognition system based on integral outline of human body. The system has three important aspects: the preprocessing of gait image, feature extraction and classification. Finally, using a method of polling to evaluate the performance of the system, and summarizing the problems existing in the gait recognition and the direction of development in the future.

A novel compact model for on-chip stacked transformers in RF-CMOS technology

NASA Astrophysics Data System (ADS)

Jun, Liu; Jincai, Wen; Qian, Zhao; Lingling, Sun

2013-08-01

A novel compact model for on-chip stacked transformers is presented. The proposed model topology gives a clear distinction to the eddy current, resistive and capacitive losses of the primary and secondary coils in the substrate. A method to analytically determine the non-ideal parasitics between the primary coil and substrate is provided. The model is further verified by the excellent match between the measured and simulated S -parameters on the extracted parameters for a 1 : 1 stacked transformer manufactured in a commercial RF-CMOS technology.

Feeling validated yet? A scoping review of the use of consumer-targeted wearable and mobile technology to measure and improve sleep.

PubMed

Baron, Kelly Glazer; Duffecy, Jennifer; Berendsen, Mark A; Cheung Mason, Ivy; Lattie, Emily G; Manalo, Natalie C

2017-12-20

The objectives of this review were to evaluate the use of consumer-targeted wearable and mobile sleep monitoring technology, identify gaps in the literature and determine the potential for use in behavioral interventions. We undertook a scoping review of studies conducted in adult populations using consumer-targeted wearable technology or mobile devices designed to measure and/or improve sleep. After screening for inclusion/exclusion criteria, data were extracted from the articles by two co-authors. Articles included in the search were using wearable or mobile technology to estimate or evaluate sleep, published in English and conducted in adult populations. Our search returned 3897 articles and 43 met our inclusion criteria. Results indicated that the majority of studies focused on validating technology to measure sleep (n = 23) or were observational studies (n = 10). Few studies were used to identify sleep disorders (n = 2), evaluate response to interventions (n = 3) or deliver interventions (n = 5). In conclusion, the use of consumer-targeted wearable and mobile sleep monitoring technology has largely focused on validation of devices and applications compared with polysomnography (PSG) but opportunities exist for observational research and for delivery of behavioral interventions. Multidisciplinary research is needed to determine the uses of these technologies in interventions as well as the use in more diverse populations including sleep disorders and other patient populations. Copyright © 2017 Elsevier Ltd. All rights reserved.

A Unique Master's Program in Combined Nuclear Technology and Nuclear Chemistry at Chalmers University of Technology, Sweden

NASA Astrophysics Data System (ADS)

Skarnemark, Gunnar; Allard, Stefan; Ekberg, Christian; Nordlund, Anders

2009-08-01

The need for engineers and scientists who can ensure safe and secure use of nuclear energy is large in Sweden and internationally. Chalmers University of Technology is therefore launching a new 2-year master's program in Nuclear Engineering, with start from the autumn of 2009. The program is open to Swedish and foreign students. The program starts with compulsory courses dealing with the basics of nuclear chemistry and physics, radiation protection, nuclear power and reactors, nuclear fuel supply, nuclear waste management and nuclear safety and security. There are also compulsory courses in nuclear industry applications and sustainable energy futures. The subsequent elective courses can be chosen freely but there is also a possibility to choose informal tracks that concentrate on nuclear chemistry or reactor technology and physics. The nuclear chemistry track comprises courses in e.g. chemistry of lanthanides, actinides and transactinides, solvent extraction, radioecology and radioanalytical chemistry and radiopharmaceuticals. The program is finished with a one semester thesis project. This is probably a unique master program in the sense of its combination of deep courses in both nuclear technology and nuclear chemistry.

NASA Technology Evaluation for Environmental Risk Mitigation Remediation Technology Collaboration Development

NASA Technical Reports Server (NTRS)

Romeo, James

2013-01-01

NASA is committed to finding solutions to agency cleanup problems that are better, cheaper, and more effective than the status quo. Unfortunately, some potential solutions involve innovative technologies for which NASA remediation managers may not have a high level of understanding or confidence. Since 2004, NASA's Stennis Space Center (SSC) in Mississippi has been pumping groundwater contaminated with trichloroethylene (TCE) and other halogenated volatile organic compounds (HVOC) from their cleanup location designated "Area G" through extraction wells to an aboveground treatment system. Over time, however, the effectiveness of this treatment strategy has diminished and an alternative approach is needed. In 2012, professionals from NASA's Principal Center for Technology Evaluation for Environmental Risk Mitigation (TEERM) introduced SSC managers to an innovative technology for enhancing the performance of SSC's existing pump and treat system. The technology, generally referred to as in situ chemical oxidation (ISCO), involves slowly and continuously injecting a strong but safe chemical oxidant into the groundwater. Treatment is enhanced by a "surfactant-type effect" which causes residual contamination from saturated soil to be released into the dissolved-phase where it can be readily oxidized. Any dissolved-phase contamination that was not oxidized can be collected by the extraction well network and treated aboveground. SSC was not familiar with the technology so to increase their confidence, TEERM identified a contractor who was willing to demonstrate their product and process at a significantly reduced price. An initial, small-scale demonstration of ISCO began at sse in March 2012 and completed in August 2012. This successful demonstration was followed by three larger-scale ISCO demonstrations between August and December 2012. The contractor's innovative Continuous Injection System (CIS) incorporated "green" and sustainable technologies and practices. A slow injection rate was maintained autonomously by the CIS, eliminating the need for multiple mobilizations of personnel and powered equipment. The CIS was calibrated to deliver only as much reagent as the formation would accept without "short circuiting", minimizing material waste. Public utility water pressure was used to mix, dilute, and inject the reagent. NASA personnel were trained to operate and maintain the system and remote monitoring and injection control capabilities were developed, further reducing the need for contractor mobilizations to the site. An integrated solar photovoltaic panel was used to power the control valves and web monitoring telemetry. SSC provided hydrogen peroxide for the process using their existing supplier for the aboveground pump and treat systems. The only consumable required from the contractor was their proprietary activator to catalyze SSC's peroxide.

A comparative study of Averrhoabilimbi extraction method

NASA Astrophysics Data System (ADS)

Zulhaimi, H. I.; Rosli, I. R.; Kasim, K. F.; Akmal, H. Muhammad; Nuradibah, M. A.; Sam, S. T.

2017-09-01

In recent year, bioactive compound in plant has become a limelight in the food and pharmaceutical market, leading to research interest to implement effective technologies for extracting bioactive substance. Therefore, this study is focusing on extraction of Averrhoabilimbi by different extraction technique namely, maceration and ultrasound-assisted extraction. Fewplant partsof Averrhoabilimbiweretaken as extraction samples which are fruits, leaves and twig. Different solvents such as methanol, ethanol and distilled water were utilized in the process. Fruit extractsresult in highest extraction yield compared to other plant parts. Ethanol and distilled water have significant role compared to methanol in all parts and both extraction technique. The result also shows that ultrasound-assisted extraction gave comparable result with maceration. Besides, the shorter period on extraction process gives useful in term of implementation to industries.

Solid Phase Micro Extraction (SPME)

NASA Technical Reports Server (NTRS)

1998-01-01

Internation Flavors and Fragrances Inc. proprietary research technology, Solid Phase Micro Extraction (SPME) utilizes a special fiber needle placed directly next to the bloom of the living flower to collect the fragrance molecules. SPME was used in the Space Flower experiment aboard STS-95 space shuttle mission, after which Dr. Braja Mookherjee (left) and Subha Patel of IFF will analyze the effects of gravity on the Overnight Scentsation rose plant.

High-speed RNA microextraction technology using magnetic oligo-dT beads and lateral magnetophoresis.

PubMed

Lee, Hwanyong; Jung, Jinhee; Han, Song-I; Han, Ki-Ho

2010-10-21

This paper presents a high-speed RNA microextractor for the direct isolation of RNA from peripheral blood lysate using magnetic oligo-dT beads. The extraction is achieved through lateral magnetophoresis, generated by a ferromagnetic wire array inlaid on a glass substrate. This RNA microextractor separated more than 80% of magnetic beads with a flow rate up to 20 ml h(-1), and the overall extraction procedure was completed within 1 min. The absorbance ratio of RNA to protein (A(260)/A(280)) was >1.7, indicating that the extraction technology yielded nearly pure RNA. The feasibility of this technique was evaluated further for its applicability to reverse transcription polymerase chain reaction (RT-PCR) procedures by performing cDNA synthesis and PCR. The analysis verified that the RNA microextractor is a practical method for easy, rapid, and high-precision RT-PCR using minimal reagent volumes without requiring highly trained personnel. In addition, it can be readily incorporated into genetic analysis procedures for realizing automated on-chip genetic platforms in a micro format.

Employing image processing techniques for cancer detection using microarray images.

PubMed

Dehghan Khalilabad, Nastaran; Hassanpour, Hamid

2017-02-01

Microarray technology is a powerful genomic tool for simultaneously studying and analyzing the behavior of thousands of genes. The analysis of images obtained from this technology plays a critical role in the detection and treatment of diseases. The aim of the current study is to develop an automated system for analyzing data from microarray images in order to detect cancerous cases. The proposed system consists of three main phases, namely image processing, data mining, and the detection of the disease. The image processing phase performs operations such as refining image rotation, gridding (locating genes) and extracting raw data from images the data mining includes normalizing the extracted data and selecting the more effective genes. Finally, via the extracted data, cancerous cell is recognized. To evaluate the performance of the proposed system, microarray database is employed which includes Breast cancer, Myeloid Leukemia and Lymphomas from the Stanford Microarray Database. The results indicate that the proposed system is able to identify the type of cancer from the data set with an accuracy of 95.45%, 94.11%, and 100%, respectively. Copyright © 2017 Elsevier Ltd. All rights reserved.

Valorisation of wastewater from two-phase olive oil extraction in fired clay brick production.

PubMed

de la Casa, José A; Lorite, Miguel; Jiménez, Juan; Castro, Eulogio

2009-09-30

Wastewater issued from oil-washing stage (OWW) in the two-phase olive oil extraction method was used to replace fresh water in clay brick manufacture. The extrusion trials were performed with one of the ceramic bodies currently being used in a local brick factory for red facing bricks (RB) production. Fresh water or OWW was added to a final consistency of 2.4 kg/cm(2), the same value as used at industrial scale for this kind of clay mixture. Comparative results of technological properties of facing bricks are presented. Results show that the products obtained with olive oil wastewater are comparable to traditional ones in terms of extrusion performance and technological properties of end products. Even dry-bending strength of the body formed by wastewater improves by 33% compared to fresh water body. In addition, heating requirements can be reduced in the range 2.4-7.3% depending on the final product. This application can alleviate environmental impacts from the olive oil extraction industry and, at the same time, result in economic savings for the brick manufacturing industry.

Medical Ultrasound Video Coding with H.265/HEVC Based on ROI Extraction

PubMed Central

Wu, Yueying; Liu, Pengyu; Gao, Yuan; Jia, Kebin

2016-01-01

High-efficiency video compression technology is of primary importance to the storage and transmission of digital medical video in modern medical communication systems. To further improve the compression performance of medical ultrasound video, two innovative technologies based on diagnostic region-of-interest (ROI) extraction using the high efficiency video coding (H.265/HEVC) standard are presented in this paper. First, an effective ROI extraction algorithm based on image textural features is proposed to strengthen the applicability of ROI detection results in the H.265/HEVC quad-tree coding structure. Second, a hierarchical coding method based on transform coefficient adjustment and a quantization parameter (QP) selection process is designed to implement the otherness encoding for ROIs and non-ROIs. Experimental results demonstrate that the proposed optimization strategy significantly improves the coding performance by achieving a BD-BR reduction of 13.52% and a BD-PSNR gain of 1.16 dB on average compared to H.265/HEVC (HM15.0). The proposed medical video coding algorithm is expected to satisfy low bit-rate compression requirements for modern medical communication systems. PMID:27814367

Bisphenol A, 4-t-octylphenol, and 4-nonylphenol determination in serum by Hybrid Solid Phase Extraction-Precipitation Technology technique tailored to liquid chromatography-tandem mass spectrometry.

PubMed

Asimakopoulos, Alexandros G; Thomaidis, Nikolaos S

2015-04-01

A rapid liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and optimized for the simultaneous determination of bisphenol A, 4-t-octylphenol and 4-nonylphenol in human blood serum. For the first time, the electrospray ionization (ESI) parameters of probe position, voltage potential, sheath gas flow rate, auxiliary gas flow rate, and ion transfer tube temperature were thoroughly studied and optimized for each phenol by a univariate approach. As a consequence, low instrumental limits of detection were reported, demonstrating at 0.2 ng/mL (in solvent matrix) excellent injection repeatability (RSD<14.5%) and a confirmation peak for all target phenols. Extraction and purification of serum was performed by the novel Hybrid Solid Phase Extraction-Precipitation Technology technique (Hybrid SPE-PPT). The limits of detection in human blood serum were 0.80, 1.3 and 1.4 ng/mL for BPA, 4-t-OP and 4-NP, respectively. Copyright © 2015 Elsevier B.V. All rights reserved.

Medical Ultrasound Video Coding with H.265/HEVC Based on ROI Extraction.

PubMed

Wu, Yueying; Liu, Pengyu; Gao, Yuan; Jia, Kebin

2016-01-01

High-efficiency video compression technology is of primary importance to the storage and transmission of digital medical video in modern medical communication systems. To further improve the compression performance of medical ultrasound video, two innovative technologies based on diagnostic region-of-interest (ROI) extraction using the high efficiency video coding (H.265/HEVC) standard are presented in this paper. First, an effective ROI extraction algorithm based on image textural features is proposed to strengthen the applicability of ROI detection results in the H.265/HEVC quad-tree coding structure. Second, a hierarchical coding method based on transform coefficient adjustment and a quantization parameter (QP) selection process is designed to implement the otherness encoding for ROIs and non-ROIs. Experimental results demonstrate that the proposed optimization strategy significantly improves the coding performance by achieving a BD-BR reduction of 13.52% and a BD-PSNR gain of 1.16 dB on average compared to H.265/HEVC (HM15.0). The proposed medical video coding algorithm is expected to satisfy low bit-rate compression requirements for modern medical communication systems.

Solvent extraction of Cu, Mo, V, and U from leach solutions of copper ore and flotation tailings.

PubMed

Smolinski, Tomasz; Wawszczak, Danuta; Deptula, Andrzej; Lada, Wieslawa; Olczak, Tadeusz; Rogowski, Marcin; Pyszynska, Marta; Chmielewski, Andrzej Grzegorz

2017-01-01

Flotation tailings from copper production are deposits of copper and other valuable metals, such as Mo, V and U. New hydrometallurgical technologies are more economical and open up new possibilities for metal recovery. This work presents results of the study on the extraction of copper by mixed extractant consisting p -toluidine dissolved in toluene. The possibility of simultaneous liquid-liquid extraction of molybdenum and vanadium was examined. D2EHPA solutions was used as extractant, and recovery of individual elements compared for the representative samples of ore and copper flotation tailings. Radiometric methods were applied for process optimization.

Optimization of conditions for supercritical fluid extraction of flavonoids from hops (Humulus lupulus L.)*

PubMed Central

He, Guo-qing; Xiong, Hao-ping; Chen, Qi-he; Ruan, Hui; Wang, Zhao-yue; Traoré, Lonseny

2005-01-01

Waste hops are good sources of flavonoids. Extraction of flavonoids from waste hops (SC-CO2 extracted hops) using supercritical fluids technology was investigated. Various temperatures, pressures and concentrations of ethanol (modifier) and the ratio (w/w) of solvent to material were tested in this study. The results of single factor and orthogonal experiments showed that at 50 °C, 25 MPa, the ratio of solvent to material (50%), ethanol concentration (80%) resulted in maximum extraction yield flavonoids (7.8 mg/g). HPLC-MS analysis of the extracts indicated that flavonoids obtained were xanthohumol, the principal prenylflavonoid in hops. PMID:16187413

Method 1664: N-hexane extractable material (hem) and silica gel treated n-hexane extractable material (SGT-HEM) by extraction and gravimetry (oil and grease and total petroleum hydrocarbons), April 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Method 1664 was developed by the United States Environmental Protection Agency Office of Science and Technology to replace previously used gravimetric procedures that employed Freon-113, a Class I CFC, as the extraction solvent for the determination of oil and grease and petroleum hydrocarbons. Method 1664 is a performance-based method applicable to aqueous matrices that requires the use of n-hexane as the extraction solvent and gravimetry as the determinative technique. In addition, QC procedures designed to monitor precision and accuracy have been incorporated into Method 1664.

Social license to operate: case from brazilian mining industry

NASA Astrophysics Data System (ADS)

Santiago, Ana Lúcia F.; Demajorovic, Jacques; Aledo, Antonio

2015-04-01

The approach of the Social License to Operate (SLO) emerges as an important element in academic discussions and business practices related to extractive industries. It appears that in productive activities with great potential to produce economic, social and environmental impacts, conventional approaches based on legal compliance no longer sufficient to legitimize the actions of companies and engagement stakeholders. Studies highlight the need of mining activities receiving a SLO "issued" by companies stakeholders, including society, government, non-governmental organizations, media and communities. However, local communities appears as major stakeholders in governance arrangements, by virtue of its proximity to extractive areas and ability to affect the company's results. Stakeholders with unmet expectations can generate conflicts and risks to the company, the knowledge of these expectations and an awareness of company managers of the importance of Social License to Operate (SLO), can generate strategies and mitigating actions to prevent and or minimize possible conflicts. The concept of SLO arises in engineering extractive industry, when you need to respond to social challenges, beyond the usual environmental challenges, technological and management. According to Franks and Cohen (2012) there is a tendency of engineering sectors, sustainability, environmental, safety and especially in risk mappings, treat the technological issues in a neutral manner, separating the technological research projects of social influences. I want to contribute to the advancement of the debate on stakeholder engagement and adopting as focus on the company's relationship with the community, the aim of this study was to understand how a social project held by one of the largest mining companies in Brazil contributed to the process of SLO. This methodological procedure adopted was a qualitative, descriptive, and exploratory interviews with the communities located in rural areas of direct influence of the company's approach. The results show that the strategy adopted by the company contributed to the process of SLO, furthermore it is necessary adopt strong methodologies that facilitate the engagement processes of the other company's stakeholders, as well as the challenge to keep on local legitimacy earned. Key words: Mining, social license to operate (SLO), social impact, corporate social responsibility, stakeholders. References: * FRANKS, DANIEL M.; COHEN, TAMAR. Social Licence in Design: Constructive technology assessment within a mineral research and development institution. Centre for Social Responsibility in Mining, Sustainable Minerals Institute, University of Queensland, Australia. 79 122 Technological Forecasting & Social Change. 2012.

Current experiences in applied underground coal gasification

NASA Astrophysics Data System (ADS)

Peters, Justyn

2010-05-01

The world is experiencing greater stress on its ability to mine and exploit energy resources such as coal, through traditional mining methods. The resources available by extraction from traditional mining methods will have a finite time and quantity. In addition, the high quality coals available are becoming more difficult to find substantially increasing exploration costs. Subsequently, new methods of extraction are being considered to improve the ability to unlock the energy from deep coals and improve the efficiency of the exploitation of the resources while also considering the mitigation of global warming. Underground Coal Gasification (UCG) is a leading commercial technology that is able to maximize the exploitation of the deep coal through extraction of the coal as a syngas (CO and H2) in situ. The syngas is then brought to the surface and efficiently utilized in any of combined cycle power generation, liquid hydrocarbon transport fuel production, fertilizer production or polymer production. Commercial UCG has been successfully operating for more than 50 years at the Yerostigaz facility in Angren, Uzbekistan. Yerostigaz is the only remaining UCG site in the former Soviet Union. Linc Energy currently owns 91.6% of this facility. UCG produces a high quality synthetic gas (syngas), containing carbon monoxide, hydrogen and methane. UCG produced syngas can be economically used for a variety of purposes, including: the production of liquid fuels when combined with Gas to Liquids (GTL) technology power generation in gas turbine combined cycle power stations a feedstock for different petrochemical processes, for example producing chemicals or other gases such as hydrogen, methane, ammonia, methanol and dimethyl ether Linc Energy has proven the combined use of UCG to Gas to Liquids (GTL) technologies. UCG to GTL technologies have the ability to provide energy alternatives to address increasing global demand for energy products. With these technologies, Linc Energy is set to become the leading producer of cleaner liquid fuels and other associated products. UCG has now been developed to a point where the commercialisation of the process is no longer questioned, the economics of the process are compelling, and is now seen as a method that resolves energy security for countries that have access to deep coal previously thought to have no economic value.

American Indian Systems for Natural Resource Management.

ERIC Educational Resources Information Center

Quintana, Jorge O.

1992-01-01

Outlines the philosophy and general principles of "primitive" indigenous production technologies and natural resource management systems in North and South America. Discusses indigenous practices that promote sustainable production in gathering, hunting and fishing, minerals extraction, and agriculture. (SV)

Analysis of DNA methylation in FFPE tissues using the MethyLight technology.

PubMed

Dallol, Ashraf; Al-Ali, Waleed; Al-Shaibani, Amina; Al-Mulla, Fahd

2011-01-01

Novel biomarkers are sought after by mining DNA extracted from formalin-fixed, paraffin-embedded (FFPE) tissues. Such tissues offer the great advantage of often having complete clinical data (including survival), as well as the tissues are amenable for laser microdissection targeting specific tissue areas. Downstream analysis of such DNA includes mutational screens and methylation profiling. Screening for mutations by sequencing requires a significant amount of DNA for PCR and cycle sequencing. This is self-inhibitory if the gene screened has a large number of exons. Profiling DNA methylation using the MethyLight technology circumvents this problem and allows for the mining of several biomarkers from DNA extracted from a single microscope slide of the tissue of interest. We describe in this chapter a detailed protocol for MethyLight and its use in the determination of CpG Island Methylator Phenotype status in FFPE colorectal cancer samples.

Healthy reduced-fat Bologna sausages enriched in ALA and DHA and stabilized with Melissa officinalis extract.

PubMed

Berasategi, Izaskun; Navarro-Blasco, Iñigo; Calvo, Maria Isabel; Cavero, Rita Yolanda; Astiasarán, Iciar; Ansorena, Diana

2014-03-01

Reduced-energy and reduced-fat Bologna products enriched with ω-3 polyunsaturated fatty acids were formulated by replacing the pork back-fat by an oil-in-water emulsion containing a mixture of linseed-algae oil stabilized with a lyophilized Melissa officinalis extract. Healthier composition and lipid profile was obtained: 85 kcal/100 g, 3.6% fat, 0.6 g ALA and 0.44 g DHA per 100 g of product and ω-6/ω-3 ratio of 0.4. Technological and sensory problems were not detected in the new formulations. Reformulation did not cause oxidation problems during 32 days of storage under refrigeration. The results suggest that it is possible to obtain reduced-fat Bologna-type sausages rich in ALA and DHA and stabilized with natural antioxidants, applying the appropriate technology without significant effects on the sensory quality, yielding interesting products from a nutritional point of view. © 2013.

EBCO Technologies TR Cyclotrons, Dynamics, Equipment, and Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, R.R.; Univ British Columbia; Erdman, K. L.

2003-08-26

The Ebco Technologies TR cyclotrons have a common parent in the 500 MeV negative ion cyclotron at TRIUMF in Vancouver. As such, the TR cyclotrons have features that can be adapted for specific application. The cyclotron design is modularized into ion source and injection system, central region and then extraction. The cyclotron ion source is configured for cyclotron beam currents ranging from 50 microAmps to 2 milliAmps. The injection line can be operated in either continuous (CW) or in pulsed mode. The center region of the cyclotron is configured to match the ion source configuration. The extracted beams are directedmore » either to a local target station or to beam lines and thence to target stations. There has been development both in solid, liquid and gas targets. There has been development in radioisotope handling techniques, target material recovery and radiochemical synthesis.« less

Rapid matching of stereo vision based on fringe projection profilometry

NASA Astrophysics Data System (ADS)

Zhang, Ruihua; Xiao, Yi; Cao, Jian; Guo, Hongwei

2016-09-01

As the most important core part of stereo vision, there are still many problems to solve in stereo matching technology. For smooth surfaces on which feature points are not easy to extract, this paper adds a projector into stereo vision measurement system based on fringe projection techniques, according to the corresponding point phases which extracted from the left and right camera images are the same, to realize rapid matching of stereo vision. And the mathematical model of measurement system is established and the three-dimensional (3D) surface of the measured object is reconstructed. This measurement method can not only broaden application fields of optical 3D measurement technology, and enrich knowledge achievements in the field of optical 3D measurement, but also provide potential possibility for the commercialized measurement system in practical projects, which has very important scientific research significance and economic value.

Maintaining space in localized ridge augmentation using guided bone regeneration with tenting screw technology.

PubMed

Chasioti, Evdokia; Chiang, Tat Fai; Drew, Howard J

2013-01-01

Prosthetic guided implant surgery requires adequate ridge dimensions for proper implant placement. Various surgical procedures can be used to augment deficient alveolar ridges. Studies have examined new bone formation on deficient ridges, utilizing numerous surgical techniques and biomaterials. The goal is to develop time efficient techniques, which have low morbidity. A crucial factor for successful bone grafting procedures is space maintenance. The article discusses space maintenance tenting screws, used in conjunction with bone allografts and resorbable barrier membranes, to ensure uneventful guided bone regeneration (GBR) enabling optimal implant positioning. The technique utilized has been described in the literature to treat severely resorbed alveolar ridges and additionally can be considered in restoring the vertical and horizontal component of deficient extraction sites. Three cases are presented to illustrate the utilization and effectiveness of tenting screw technology in the treatment of atrophic extraction sockets and for deficient ridges.

A Technological Comparison of Six Processes for the Production of Reduction-Grade Alumina from Non-Bauxitic Raw Materials

NASA Astrophysics Data System (ADS)

Bengtson, K. B.

The U. S. Bureau of Mines, by means of a contract with Kaiser Engineers and with Kaiser Aluminum & Chemical Corporation as a subcontractor, has sponsored a technological and an economic evaluation of six candidate processes for the manufacture of alumina from certain U. S. raw materials other than bauxite. This paper describes each process. Flow diagrams and the total energy requirement for each process are included. Important characteristics affecting the economics of producing alumina by each process are discussed, and some presently unsolved technical problems are identified. The extraction of alumina from clay via hydrochloric acid with iron separation by solvent extraction, and the crystallization of intermediate AlCl3·6H2O through the introduction of HCl gas into the pregnant mother liquor, appears to be technically feasible and the most attractive of the six raw material/process combinations.

Dust Mitigation for Martian Exploration

NASA Technical Reports Server (NTRS)

Williams, Blakeley Shay

2011-01-01

One of the efforts of the In-Situ Resource Utilization project is to extract oxygen, fuel, and water from the Martian air. However, the surface of Mars is covered in a layer of dust, which is uploaded into the atmosphere by dust devils and dust storms. This atmospheric dust would be collected along with the air during the conversion process. Thus, it is essential to extract the dust from the air prior to commencing the conversion. An electrostatic precipitator is a commonly used dust removal technology on earth. Using this technology, dust particles that pass through receive an electrostatic charge by means of a corona discharge. The particles are then driven to a collector in a region of high electric field at the center of the precipitator. Experiments were conducted to develop a precipitator that will function properly in the Martian atmosphere, which has a very low pressure and is made up . of primarily carbon dioxide.

Colorimetric Solid Phase Extraction for the Measurement of Total I (Iodine, Iodide, and Triiodide) in Spacecraft Drinking Water

NASA Technical Reports Server (NTRS)

Lipert, Robert J.; Porter, Marc D.; Siperko, Lorraine M.; Gazda, Daniel B.; Rutz, Jeff A.; Schultz, John R.; Carrizales, Stephanie M.; McCoy, J. Torin

2009-01-01

An experimental drinking water monitoring kit for the measurement of iodine and silver(I) was recently delivered to the International Space Station (ISS). The kit is based on Colorimetric Solid Phase Extraction (CSPE) technology, which measures the change in diffuse reflectance of indicator disks following exposure to a water sample. To satisfy additional spacecraft water monitoring requirements, CSPE has now been extended to encompass the measurement of total I (iodine, iodide, and triiodide) through the introduction of an oxidizing agent, which converts iodide and triiodide to iodine, for measurement using the same indicator disks currently being tested on ISS. These disks detect iodine, but are insensitive to iodide and triiodide. We report here the operational considerations, design, and ground-based performance of the CSPE method for total I. The results demonstrate that CSPE technology is poised to meet NASA's total I monitoring requirements.

Neuroimaging Feature Terminology: A Controlled Terminology for the Annotation of Brain Imaging Features.

PubMed

Iyappan, Anandhi; Younesi, Erfan; Redolfi, Alberto; Vrooman, Henri; Khanna, Shashank; Frisoni, Giovanni B; Hofmann-Apitius, Martin

2017-01-01

Ontologies and terminologies are used for interoperability of knowledge and data in a standard manner among interdisciplinary research groups. Existing imaging ontologies capture general aspects of the imaging domain as a whole such as methodological concepts or calibrations of imaging instruments. However, none of the existing ontologies covers the diagnostic features measured by imaging technologies in the context of neurodegenerative diseases. Therefore, the Neuro-Imaging Feature Terminology (NIFT) was developed to organize the knowledge domain of measured brain features in association with neurodegenerative diseases by imaging technologies. The purpose is to identify quantitative imaging biomarkers that can be extracted from multi-modal brain imaging data. This terminology attempts to cover measured features and parameters in brain scans relevant to disease progression. In this paper, we demonstrate the systematic retrieval of measured indices from literature and how the extracted knowledge can be further used for disease modeling that integrates neuroimaging features with molecular processes.

The Agent of extracting Internet Information with Lead Order

NASA Astrophysics Data System (ADS)

Mo, Zan; Huang, Chuliang; Liu, Aijun

In order to carry out e-commerce better, advanced technologies to access business information are in need urgently. An agent is described to deal with the problems of extracting internet information that caused by the non-standard and skimble-scamble structure of Chinese websites. The agent designed includes three modules which respond to the process of extracting information separately. A method of HTTP tree and a kind of Lead algorithm is proposed to generate a lead order, with which the required web can be retrieved easily. How to transform the extracted information structuralized with natural language is also discussed.

Apparatus and method for extraction of chemicals from aquifer remediation effluent water

DOEpatents

McMurtrey, Ryan D.; Ginosar, Daniel M.; Moor, Kenneth S.; Shook, G. Michael; Moses, John M.; Barker, Donna L.

2002-01-01

An apparatus and method for extraction of chemicals from an aquifer remediation aqueous effluent are provided. The extraction method utilizes a critical fluid for separation and recovery of chemicals employed in remediating aquifers contaminated with hazardous organic substances, and is particularly suited for separation and recovery of organic contaminants and process chemicals used in surfactant-based remediation technologies. The extraction method separates and recovers high-value chemicals from the remediation effluent and minimizes the volume of generated hazardous waste. The recovered chemicals can be recycled to the remediation process or stored for later use.

Method and system for extraction of chemicals from aquifer remediation effluent water

DOEpatents

McMurtrey, Ryan D.; Ginosar, Daniel M.; Moor, Kenneth S.; Shook, G. Michael; Barker, Donna L.

2003-01-01

A method and system for extraction of chemicals from an groundwater remediation aqueous effluent are provided. The extraction method utilizes a critical fluid for separation and recovery of chemicals employed in remediating groundwater contaminated with hazardous organic substances, and is particularly suited for separation and recovery of organic contaminants and process chemicals used in surfactant-based remediation technologies. The extraction method separates and recovers high-value chemicals from the remediation effluent and minimizes the volume of generated hazardous waste. The recovered chemicals can be recycled to the remediation process or stored for later use.

An integrated system for land resources supervision based on the IoT and cloud computing

NASA Astrophysics Data System (ADS)

Fang, Shifeng; Zhu, Yunqiang; Xu, Lida; Zhang, Jinqu; Zhou, Peiji; Luo, Kan; Yang, Jie

2017-01-01

Integrated information systems are important safeguards for the utilisation and development of land resources. Information technologies, including the Internet of Things (IoT) and cloud computing, are inevitable requirements for the quality and efficiency of land resources supervision tasks. In this study, an economical and highly efficient supervision system for land resources has been established based on IoT and cloud computing technologies; a novel online and offline integrated system with synchronised internal and field data that includes the entire process of 'discovering breaches, analysing problems, verifying fieldwork and investigating cases' was constructed. The system integrates key technologies, such as the automatic extraction of high-precision information based on remote sensing, semantic ontology-based technology to excavate and discriminate public sentiment on the Internet that is related to illegal incidents, high-performance parallel computing based on MapReduce, uniform storing and compressing (bitwise) technology, global positioning system data communication and data synchronisation mode, intelligent recognition and four-level ('device, transfer, system and data') safety control technology. The integrated system based on a 'One Map' platform has been officially implemented by the Department of Land and Resources of Guizhou Province, China, and was found to significantly increase the efficiency and level of land resources supervision. The system promoted the overall development of informatisation in fields related to land resource management.

Investigations into the application of a combination of bioventing and biotrickling filter technologies for soil decontamination processes--a transition regime between bioventing and soil vapour extraction.

PubMed

Magalhães, S M C; Ferreira Jorge, R M; Castro, P M L

2009-10-30

Bioventing has emerged as one of the most cost-effective in situ technologies available to address petroleum light-hydrocarbon spills, one of the most common sources of soil pollution. However, the major drawback associated with this technology is the extended treatment time often required. The present study aimed to illustrate how an intended air-injection bioventing technology can be transformed into a soil vapour extraction effort when the air flow rates are pushed to a stripping mode, thus leading to the treatment of the off-gas resulting from volatilisation. As such, a combination of an air-injection bioventing system and a biotrickling filter was applied for the treatment of contaminated soil, the latter aiming at the treatment of the emissions resulting from the bioventing process. With a moisture content of 10%, soil contaminated with toluene at two different concentrations, namely 2 and 14 mg g soil(-1), were treated successfully using an air-injection bioventing system at a constant air flow rate of ca. 0.13 dm(3) min(-1), which led to the removal of ca. 99% toluene, after a period of ca. 5 days of treatment. A biotrickling filter was simultaneously used to treat the outlet gas emissions, which presented average removal efficiencies of ca. 86%. The proposed combination of biotechnologies proved to be an efficient solution for the decontamination process, when an excessive air flow rate was applied, reducing both the soil contamination and the outlet gas emissions, whilst being able to reduce the treatment time required by bioventing only.

Proposed correlation of modern processing principles for Ayurvedic herbal drug manufacturing: A systematic review.

PubMed

Jain, Rahi; Venkatasubramanian, Padma

2014-01-01

Quality Ayurvedic herbal medicines are potential, low-cost solutions for addressing contemporary healthcare needs of both Indian and global community. Correlating Ayurvedic herbal preparations with modern processing principles (MPPs) can help develop new and use appropriate technology for scaling up production of the medicines, which is necessary to meet the growing demand. Understanding the fundamental Ayurvedic principles behind formulation and processing is also important for improving the dosage forms. Even though Ayurvedic industry has adopted technologies from food, chemical and pharmaceutical industries, there is no systematic study to correlate the traditional and modern processing methods. This study is an attempt to provide a possible correlation between the Ayurvedic processing methods and MPPs. A systematic literature review was performed to identify the Ayurvedic processing methods by collecting information from English editions of classical Ayurveda texts on medicine preparation methods. Correlation between traditional and MPPs was done based on the techniques used in Ayurvedic drug processing. It was observed that in Ayurvedic medicine preparations there were two major types of processes, namely extraction, and separation. Extraction uses membrane rupturing and solute diffusion principles, while separation uses volatility, adsorption, and size-exclusion principles. The study provides systematic documentation of methods used in Ayurveda for herbal drug preparation along with its interpretation in terms of MPPs. This is the first step which can enable improving or replacing traditional techniques. New technologies or use of existing technologies can be used to improve the dosage forms and scaling up while maintaining the Ayurvedic principles similar to traditional techniques.

Microbes, metagenomes and marine mammals: enabling the next generation of scientist to enter the genomic era

PubMed Central

2013-01-01

Background The revolution in DNA sequencing technology continues unabated, and is affecting all aspects of the biological and medical sciences. The training and recruitment of the next generation of researchers who are able to use and exploit the new technology is severely lacking and potentially negatively influencing research and development efforts to advance genome biology. Here we present a cross-disciplinary course that provides undergraduate students with practical experience in running a next generation sequencing instrument through to the analysis and annotation of the generated DNA sequences. Results Many labs across world are installing next generation sequencing technology and we show that the undergraduate students produce quality sequence data and were excited to participate in cutting edge research. The students conducted the work flow from DNA extraction, library preparation, running the sequencing instrument, to the extraction and analysis of the data. They sequenced microbes, metagenomes, and a marine mammal, the Californian sea lion, Zalophus californianus. The students met sequencing quality controls, had no detectable contamination in the targeted DNA sequences, provided publication quality data, and became part of an international collaboration to investigate carcinomas in carnivores. Conclusions Students learned important skills for their future education and career opportunities, and a perceived increase in students’ ability to conduct independent scientific research was measured. DNA sequencing is rapidly expanding in the life sciences. Teaching undergraduates to use the latest technology to sequence genomic DNA ensures they are ready to meet the challenges of the genomic era and allows them to participate in annotating the tree of life. PMID:24007365

Mercury ion thruster technology

NASA Technical Reports Server (NTRS)

Beattie, J. R.; Matossian, J. N.

1989-01-01

The Mercury Ion Thruster Technology program was an investigation for improving the understanding of state-of-the-art mercury ion thrusters. Emphasis was placed on optimizing the performance and simplifying the design of the 30 cm diameter ring-cusp discharge chamber. Thruster performance was improved considerably; the baseline beam-ion production cost of the optimized configuration was reduced to Epsilon (sub i) perspective to 130 eV/ion. At a discharge propellant-utilization efficiency of 95 percent, the beam-ion production cost was reduced to about 155 eV/ion, representing a reduction of about 40 eV/ion over the corresponding value for the 30 cm diameter J-series thruster. Comprehensive Langmuir-probe surveys were obtained and compared with similar measurements for a J-series thruster. A successful volume-averaging scheme was developed to correlate thruster performance with the dominant plasma processes that prevail in the two thruster designs. The average Maxwellian electron temperature in the optimized ring-cusp design is as much as 1 eV higher than it is in the J-series thruster. Advances in ion-extraction electrode fabrication technology were made by improving materials selection criteria, hydroforming and stress-relieving tooling, and fabrications procedures. An ion-extraction performance study was conducted to assess the effect of screen aperture size on ion-optics performance and to verify the effectiveness of a beam-vectoring model for three-grid ion optics. An assessment of the technology readiness of the J-series thruster was completed, and operation of an 8 cm IAPS thruster using a simplified power processor was demonstrated.

Successful isolation and PCR amplification of DNA from National Institute of Standards and Technology herbal dietary supplement standard reference material powders and extracts.

PubMed

Cimino, Matthew T

2010-03-01

Twenty-four herbal dietary supplement powder and extract reference standards provided by the National Institute of Standards and Technology (NIST) were investigated using three different commercially available DNA extraction kits to evaluate DNA availability for downstream nucleotide-based applications. The material included samples of Camellia, Citrus, Ephedra, Ginkgo, Hypericum, Serenoa, And Vaccinium. Protocols from Qiagen, MoBio, and Phytopure were used to isolate and purify DNA from the NIST standards. The resulting DNA concentration was quantified using SYBR Green fluorometry. Each of the 24 samples yielded DNA, though the concentration of DNA from each approach was notably different. The Phytopure method consistently yielded more DNA. The average yield ratio was 22 : 3 : 1 (ng/microL; Phytopure : Qiagen : MoBio). Amplification of the internal transcribed spacer II region using PCR was ultimately successful in 22 of the 24 samples. Direct sequencing chromatograms of the amplified material suggested that most of the samples were comprised of mixtures. However, the sequencing chromatograms of 12 of the 24 samples were sufficient to confirm the identity of the target material. The successful extraction, amplification, and sequencing of DNA from these herbal dietary supplement extracts and powders supports a continued effort to explore nucleotide sequence-based tools for the authentication and identification of plants in dietary supplements. (c) Georg Thieme Verlag KG Stuttgart . New York.

Comparison of commercial systems for extraction of nucleic acids from DNA/RNA respiratory pathogens.

PubMed

Yang, Genyan; Erdman, Dean E; Kodani, Maja; Kools, John; Bowen, Michael D; Fields, Barry S

2011-01-01

This study compared six automated nucleic acid extraction systems and one manual kit for their ability to recover nucleic acids from human nasal wash specimens spiked with five respiratory pathogens, representing Gram-positive bacteria (Streptococcus pyogenes), Gram-negative bacteria (Legionella pneumophila), DNA viruses (adenovirus), segmented RNA viruses (human influenza virus A), and non-segmented RNA viruses (respiratory syncytial virus). The robots and kit evaluated represent major commercially available methods that are capable of simultaneous extraction of DNA and RNA from respiratory specimens, and included platforms based on magnetic-bead technology (KingFisher mL, Biorobot EZ1, easyMAG, KingFisher Flex, and MagNA Pure Compact) or glass fiber filter technology (Biorobot MDX and the manual kit Allprep). All methods yielded extracts free of cross-contamination and RT-PCR inhibition. All automated systems recovered L. pneumophila and adenovirus DNA equivalently. However, the MagNA Pure protocol demonstrated more than 4-fold higher DNA recovery from the S. pyogenes than other methods. The KingFisher mL and easyMAG protocols provided 1- to 3-log wider linearity and extracted 3- to 4-fold more RNA from the human influenza virus and respiratory syncytial virus. These findings suggest that systems differed in nucleic acid recovery, reproducibility, and linearity in a pathogen specific manner. Published by Elsevier B.V.

[Influence of Gentiana lutea L extract on blood coagulation].

PubMed

Bakuridze, A D; Nikolaev, S M; Tsagarenshvili, N T; Kurdiani, N G; Mikaia, G A

2009-01-01

The dry extract from the terrestrial parts of Gentiana Lutea was received in accordance to the developed by us general technological scheme. Study of the pharmacological influence of obtained extract on the coagulating properties of blood revealed that after its per os instillation into experimental animals the time of the formation of active thromboplastin reliably increases, while the time of thrombin and fibrinous cluster formation is shortened in comparison with those indices in the animals, that did not receive phyto-preparation, at the same time morphological appearance of the peripheral blood remains unchanged. Dry extract of terrestrial parts of Gentiana Lutea prepared in accordance to the technology recommended by us, together with widely known pharmacological effects, is characterized with new activity - influence on haemostasis. Obtained preliminary data concerning influence of the extract on coagulation of the blood request further deep studies of its mechanism. Revealed new activity of the terrestrial parts of Gentiana Lutea and the studies of the mechanism of its activity will serve in future as a basis for the recommendation of its use in new nosology. Terrestrial parts of Gentiana lutea L. are proposed as an alternative of the underground parts of the plant. Alongside with that, it is expedient to continue the studies devoted to the development of the haemostatic remedies of plant origin with systemic and local action (sponges, films, skin glues) from terrestrial parts of Gentiana lutea L.

ON-SITE SOLID PHRASE EXTRACTION AND LABORATORY ...

EPA Pesticide Factsheets

Fragrance materials, such as synthetic musks in aqueous samples, are normally analyzed by GC/MS in the selected ion monitoring (SIM) mode to provide maximum sensitivity after liquid-liquid extraction of I -L samples. A I -L sample, however, usually provides too little analyte for full-scan data acquisition. An on-site extraction method for extracting synthetic musks from 60 L of wastewater effluent has been developed. Such a large sample volume permits high-quality, full-scan mass spectra to be obtained for various synthetic musk compounds. Quantification of these compounds was conveniently achieved from the full-scan data directly, without preparing SIM descriptors for each compound to acquire SIM data. The research focused on in the subtasks is the development and application of state-of the-art technologies to meet the needs of the public, Office of Water, and ORD in the area of Water Quality. Located In the subtasks are the various research projects being performed in support of this Task and more in-depth coverage of each project. Briefly, each project's objective is stated below.Subtask 1: To integrate state-of-the-art technologies (polar organic chemical integrative samplers, advanced solid-phase extraction methodologies with liquid chromatography/electrospray/mass spectrometry) and apply them to studying the sources and fate of a select list of PPCPs. Application and improvement of analytical methodologies that can detect non-volatile, polar, water-sol

IN SITU SOLID-PHASE EXTRACTION AND ANALYSIS OF ...

EPA Pesticide Factsheets

Fragrance materials, such as synthetic musks in aqueous samples, are normally analyzed by GC/MS in the selected ion monitoring (SIM) mode to provide maximum sensitivity after liquid-liquid extraction of 1-L samples. A 1-L sample, however, usually provides too little analyte for full-scan data acquisition.We have developed an on-site extraction method for extracting synthetic musks from 60 L of wastewater effluent. Such a large sample volume permits high-quality, full-scan mass spectra to be obtained for various synthetic musk compounds. Quantification of these compounds was conveniently achieved from the full-scan data directly, without preparing SIM descriptors for each compound to acquire SIM data. The research focused on in the subtasks is the development and application of state-of the-art technologies to meet the needs of the public, Office of Water, and ORD in the area of Water Quality. Located In the subtasks are the various research projects being performed in support of this Task and more in-depth coverage of each project. Briefly, each project's objective is stated below.Subtask 1: To integrate state-of-the-art technologies (polar organic chemical integrative samplers, advanced solid-phase extraction methodologies with liquid chromatography/electrospray/mass spectrometry) and apply them to studying the sources and fate of a select list of PPCPs. Application and improvement of analytical methodologies that can detect non-volatile, polar, water-s

Privacy Attitudes among Early Adopters of Emerging Health Technologies

PubMed Central

Cheung, Cynthia; Bietz, Matthew J.; Patrick, Kevin; Bloss, Cinnamon S.

2016-01-01

Introduction Advances in health technology such as genome sequencing and wearable sensors now allow for the collection of highly granular personal health data from individuals. It is unclear how people think about privacy in the context of these emerging health technologies. An open question is whether early adopters of these advances conceptualize privacy in different ways than non-early adopters. Purpose This study sought to understand privacy attitudes of early adopters of emerging health technologies. Methods Transcripts from in-depth, semi-structured interviews with early adopters of genome sequencing and health devices and apps were analyzed with a focus on participant attitudes and perceptions of privacy. Themes were extracted using inductive content analysis. Results Although interviewees were willing to share personal data to support scientific advancements, they still expressed concerns, as well as uncertainty about who has access to their data, and for what purpose. In short, they were not dismissive of privacy risks. Key privacy-related findings are organized into four themes as follows: first, personal data privacy; second, control over personal information; third, concerns about discrimination; and fourth, contributing personal data to science. Conclusion Early adopters of emerging health technologies appear to have more complex and nuanced conceptions of privacy than might be expected based on their adoption of personal health technologies and participation in open science. Early adopters also voiced uncertainty about the privacy implications of their decisions to use new technologies and share their data for research. Though not representative of the general public, studies of early adopters can provide important insights into evolving attitudes toward privacy in the context of emerging health technologies and personal health data research. PMID:27832194

Space technology developments in Malaysia:

NASA Astrophysics Data System (ADS)

Sabirin, A.

The venture of space is, by nature, a costly one. However, exploring space is not just an activity reserved for international superpowers. Smaller and emerging space nations, some with burgeoning space programs of their own, can play a role in space technology development and interplanetary exploration, sometimes simply by just being there. Over the past four decades, the range of services delivered by space technologies in Malaysia has grown enormously. For many business and public services, space based technologies have become the primary means of delivery of such services. Space technology development in Malaysia started with Malaysia's first microsatellite, TiungSAT-1. TiungSAT-1 has been successfully launched from the Baikonur Cosmodrome, Kazakhstan on the 26th of September 2000 on a Russian-Ukrainian Dnepr rocket. There have been wide imaging applications and information extraction using data from TiungSAT-1. Various techniques have been applied to the data for different applications in environmental assessment and monitoring as well as resource management. As a step forward, Malaysia has also initiated another space technology programme, RAZAKSAT. RAZAKSAT is a 180kg class satellite designed to provide 2.5meter ground sampling distance resolution imagery on a near equatorial orbit. Its mission objective is to demonstrate the capability of a medium high resolution remote sensing camera using a cost effective small satellite platform and a multi-channel linear push-broom electro-optical instrument. Realizing the immense benefits of space technology and its significant role in promoting sustainable development, Malaysia is committed to the continuous development and advancement of space technology within the scope of peaceful use of outer space and boosting its national economic growth through space related activities.

New Fiber Materials with Sorption Capacity at 5.0 g-U/kg Adsorbent under Marine Testing Conditions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saito, Tomonori; Brown, S.; Das, Sadananda

The Fuel Resources program of the Fuel Cycle Research and Development program of the Office of Nuclear Energy (NE) has focused on assuring that nuclear fuel resources are available in the United States for a long term. An immense source of uranium is seawater, which contains an estimated amount of 4.5 billion tonnes of dissolved uranium. Extraction of the uranium resource in seawater can provide a price cap and ensure centuries of uranium supply for future nuclear energy production. NE initiated a multidisciplinary program with participants from national laboratories, universities, and research institutes to enable technical breakthroughs related to uraniummore » recovery from seawater. The goal is to develop advanced adsorbents to make the seawater uranium recovery technology a cost competitive, viable technology. Under this program, Oak Ridge National Laboratory (ORNL) has developed several novel adsorbents, which enhanced the uranium capacity 4-5 times from the state-of-the art Japanese adsorbents. Uranium exists uniformly at a concentration of ~3.3 ppb in seawater. Because of the vast volume of the oceans, the total estimated amount of uranium in seawater is approximately 1000 times larger than its amount in terrestrial resources. However, due to the low concentration, a significant challenge remains for making the extraction of uranium from seawater a commercially viable alternative technology. The biggest challenge for this technology to overcome to efficiently reduce the extraction cost is to develop adsorbents with increased uranium adsorption capacity. Two major approaches were investigated for synthesizing novel adsorbents with enhanced uranium adsorption capacity. One method utilized conventional radiation induced graft polymerization (RIGP) to synthesize adsorbents on high-surface area trunk fibers and the other method utilized a chemical grafting technique, atom-transfer radical polymerization (ATRP). Both approaches have shown promising uranium extraction capacities: RIGP adsorbent achieved 5.00 ± 0.15 g U/kg-ads., while ATRP adsorbent achieved 6.56 ± 0.33 g U/kg-ads., after 56 days of seawater exposure. These achieved values are the highest adsorption capacities ever reported for uranium extraction from seawater. The study successfully demonstrated new fiber materials with sorption capacity at 5.0 g-U/kg adsorbent under marine testing conditions. Further optimization, investigation of other new materials as well as deepening our understanding will develop adsorbents that have even higher uranium adsorption capacity, increased selectivity, and faster kinetics.« less

Optimization and Technological Development Strategies of an Antimicrobial Extract from Achyrocline alata Assisted by Statistical Design

PubMed Central

Demarque, Daniel P.; Fitts, Sonia Maria F.; Boaretto, Amanda G.; da Silva, Júlio César Leite; Vieira, Maria C.; Franco, Vanessa N. P.; Teixeira, Caroline B.; Toffoli-Kadri, Mônica C.; Carollo, Carlos A.

2015-01-01

Achyrocline alata, known as Jateí-ka-há, is traditionally used to treat several health problems, including inflammations and infections. This study aimed to optimize an active extract against Streptococcus mutans, the main bacteria that causes caries. The extract was developed using an accelerated solvent extraction and chemometric calculations. Factorial design and response surface methodologies were used to determine the most important variables, such as active compound selectivity. The standardized extraction recovered 99% of the four main compounds, gnaphaliin, helipyrone, obtusifolin and lepidissipyrone, which represent 44% of the extract. The optimized extract of A. alata has a MIC of 62.5 μg/mL against S. mutans and could be used in mouth care products. PMID:25710523

Fabrication and vibration characterization of curcumin extracted from turmeric (Curcuma longa) rhizomes of the northern Vietnam.

PubMed

Van Nong, Hoang; Hung, Le Xuan; Thang, Pham Nam; Chinh, Vu Duc; Vu, Le Van; Dung, Phan Tien; Van Trung, Tran; Nga, Pham Thu

2016-01-01

In this report, we present the research results on using the conventional method and microwave technology to extract curcuminoid from turmeric roots originated in different regions of Northern Vietnam. This method is simple, yet economical, non-toxic and still able to achieve high extraction performance to get curcuminoid from turmeric roots. The detailed results on the Raman vibration spectra combined with X-ray powder diffraction and high-performance liquid chromatography/mass spectrometry allowed the evaluation of each batch of curcumin crystalline powder sample received, under the conditions of applied fabrication technology. Also, the absorption and fluorescence spectroscopies of the samples are presented in the paper. The information to be presented in this paper: absorption and fluorescence spectroscopies of the samples; new experimental study results on applied technology to mass-produce curcumin from turmeric rhizomes; comparative study results between fabricated samples and marketing curcumin products-to state the complexity of co-existing crystalline phase in curcumin powder samples. We noticed that, it is possible to use the vibration line at ~959 cm(-1)-characteristic of the ν C=O vibration, and the ~1625 cm(-1) line-characteristic of the ν C=O and ν C=C vibration in curcumin molecules, for preliminary quality assessment of naturally originated curcumin crystalline powder samples. Data on these new optical spectra will contribute to the bringing of detailed information on natural curcumin in Vietnam, serving research purposes and applications of natural curcumin powder and nanocurcumin in Vietnam, as well as being initial materials for the pharmaceutical, cosmetics or functional food industries.

Research on the use of data fusion technology to evaluate the state of electromechanical equipment

NASA Astrophysics Data System (ADS)

Lin, Lin

2018-04-01

Aiming at the problems of different testing information modes and the coexistence of quantitative and qualitative information in the state evaluation of electromechanical equipment, the paper proposes the use of data fusion technology to evaluate the state of electromechanical equipment. This paper introduces the state evaluation process of mechanical and electrical equipment in detail, uses the D-S evidence theory to fuse the decision-making layers of mechanical and electrical equipment state evaluation and carries out simulation tests. The simulation results show that it is feasible and effective to apply the data fusion technology to the state evaluation of the mechatronic equipment. After the multiple decision-making information provided by different evaluation methods are fused repeatedly and the useful information is extracted repeatedly, the fuzziness of judgment can be reduced and the state evaluation Credibility.

Decontamination of produced water containing petroleum hydrocarbons by electrochemical methods: a minireview.

PubMed

dos Santos, Elisama Vieira; Bezerra Rocha, Jessica Horacina; de Araújo, Danyelle Medeiros; de Moura, Dayanne Chianca; Martínez-Huitle, Carlos Alberto

2014-01-01

Produced water (PW) is the largest waste stream generated in oil and gas industries. The drilling and extraction operations that are aimed to maximize the production of oil may be counterbalanced by the huge production of contaminated water (called PW) with pollutants, such as heavy metals, dissolved/suspended solids, and organic compounds. PW is conventionally treated through different physical, chemical, and biological methods. In offshore platforms, because of space constraints, compact physical and chemical systems are used. However, major research efforts are being developed with innovative technologies for treating PW in order to comply with reuse and discharge limits. Among them, electrochemical technologies have been proposed as a promising alternative for the treatment of this kind of wastewaters. Then, this paper presents a minireview of efficient electrochemical technologies used until now for treating PW generated by petrochemical industry.

Photolytic AND Catalytic Destruction of Organic Waste Water Pollutants

NASA Astrophysics Data System (ADS)

Torosyan, V. F.; Torosyan, E. S.; Kryuchkova, S. O.; Gromov, V. E.

2017-01-01

The system: water supply source - potable and industrial water - wastewater - sewage treatment - water supply source is necessary for water supply and efficient utilization of water resources. Up-to-date technologies of waste water biological treatment require for special microorganisms, which are technologically complex and expensive but unable to solve all the problems. Application of photolytic and catalytically-oxidizing destruction is quite promising. However, the most reagents are strong oxidizers in catalytic oxidation of organic substances and can initiate toxic substance generation. Methodic and scientific approaches to assess bread making industry influence on the environment have been developed in this paper in order to support forecasting and taking technological decisions concerning reduction of this influence. Destructive methods have been tested: ultra violet irradiation and catalytic oxidation for extraction of organic compounds from waste water by natural reagents.

A new patent-based approach for technology mapping in the pharmaceutical domain.

PubMed

Russo, Davide; Montecchi, Tiziano; Carrara, Paolo

2013-09-01

The key factor in decision-making is the quality of information collected and processed in the problem analysis. In most cases, patents represent a very important source of information. The main problem is how to extract such information from the huge corpus of documents with a high recall and precision, and in a short time. This article demonstrates a patent search and classification method, called Knowledge Organizing Module, which consists of creating, almost automatically, a pool of patents based on polysemy expansion and homonymy disambiguation. Since the pool is done, an automatic patent technology landscaping is provided for fixing the state of the art of our product, and exploring competing alternative treatments and/or possible technological opportunities. An exemplary case study is provided, it deals with a patent analysis in the field of verruca treatments.

Research on key technology of prognostic and health management for autonomous underwater vehicle

NASA Astrophysics Data System (ADS)

Zhou, Zhi

2017-12-01

Autonomous Underwater Vehicles (AUVs) are non-cable and autonomous motional underwater robotics. With a wide range of activities, it can reach thousands of kilometers. Because it has the advantages of wide range, good maneuverability, safety and intellectualization, it becomes an important tool for various underwater tasks. How to improve diagnosis accuracy of the AUVs electrical system faults, and how to repair AUVs by the information are the focus of navy in the world. In turn, ensuring safe and reliable operation of the system has very important significance to improve AUVs sailing performance. To solve these problems, in the paper the prognostic and health management(PHM) technology is researched and used to AUV, and the overall framework and key technology are proposed, such as data acquisition, feature extraction, fault diagnosis, failure prediction and so on.

State of the Art, Trends and Future of Bluetooth Low Energy, Near Field Communication and Visible Light Communication in the Development of Smart Cities

PubMed Central

Cerruela García, Gonzalo; Luque Ruiz, Irene; Gómez-Nieto, Miguel Ángel

2016-01-01

The current social impact of new technologies has produced major changes in all areas of society, creating the concept of a smart city supported by an electronic infrastructure, telecommunications and information technology. This paper presents a review of Bluetooth Low Energy (BLE), Near Field Communication (NFC) and Visible Light Communication (VLC) and their use and influence within different areas of the development of the smart city. The document also presents a review of Big Data Solutions for the management of information and the extraction of knowledge in an environment where things are connected by an “Internet of Things” (IoT) network. Lastly, we present how these technologies can be combined together to benefit the development of the smart city. PMID:27886087

Object-oriented recognition of high-resolution remote sensing image

NASA Astrophysics Data System (ADS)

Wang, Yongyan; Li, Haitao; Chen, Hong; Xu, Yuannan

2016-01-01

With the development of remote sensing imaging technology and the improvement of multi-source image's resolution in satellite visible light, multi-spectral and hyper spectral , the high resolution remote sensing image has been widely used in various fields, for example military field, surveying and mapping, geophysical prospecting, environment and so forth. In remote sensing image, the segmentation of ground targets, feature extraction and the technology of automatic recognition are the hotspot and difficulty in the research of modern information technology. This paper also presents an object-oriented remote sensing image scene classification method. The method is consist of vehicles typical objects classification generation, nonparametric density estimation theory, mean shift segmentation theory, multi-scale corner detection algorithm, local shape matching algorithm based on template. Remote sensing vehicles image classification software system is designed and implemented to meet the requirements .

Biologically Inspired Technology Using Electroactive Polymers (EAP)

NASA Technical Reports Server (NTRS)

Bar-Cohen, Yoseph

2006-01-01

Evolution allowed nature to introduce highly effective biological mechanisms that are incredible inspiration for innovation. Humans have always made efforts to imitate nature's inventions and we are increasingly making advances that it becomes significantly easier to imitate, copy, and adapt biological methods, processes and systems. This brought us to the ability to create technology that is far beyond the simple mimicking of nature. Having better tools to understand and to implement nature's principles we are now equipped like never before to be inspired by nature and to employ our tools in far superior ways. Effectively, by bio-inspiration we can have a better view and value of nature capability while studying its models to learn what can be extracted, copied or adapted. Using electroactive polymers (EAP) as artificial muscles is adding an important element to the development of biologically inspired technologies.

[Application progress on near infrared spectroscopy in quality control and process monitoring of traditional Chinese medicine].

PubMed

Li, Wenlong; Qu, Haibin

2017-01-25

The industry of traditional Chinese medicine (TCM) encounters problems like quality fluctuation of raw materials and unstandardized production process. Near infrared (NIR) spectroscopy technology is widely used in quality control of TCM because of its abundant information, fast and nondestructive characters. The main applications include quantitative analysis of Chinese medicinal materials, intermediates and Chinese patent medicines; the authenticity of TCM, species, origins and manufacturers; monitoring and control of the extraction, alcohol precipitation, column chromatography and blending process. This article reviews the progress on the application of NIR spectroscopy technology in TCM field. In view of the problems existing in the application, the article proposes that the standardization of NIR analysis method should be developed according to specific characteristics of TCM, which will promote the application of NIR technology in the TCM industry.

A review on hydrothermal pre-treatment technologies and environmental profiles of algal biomass processing.

PubMed

Patel, Bhavish; Guo, Miao; Izadpanah, Arash; Shah, Nilay; Hellgardt, Klaus

2016-01-01

The need for efficient and clean biomass conversion technologies has propelled Hydrothermal (HT) processing as a promising treatment option for biofuel production. This manuscript discussed its application for pre-treatment of microalgae biomass to solid (biochar), liquid (biocrude and biodiesel) and gaseous (hydrogen and methane) products via Hydrothermal Carbonisation (HTC), Hydrothermal Liquefaction (HTL) and Supercritical Water Gasification (SCWG) as well as the utility of HT water as an extraction medium and HT Hydrotreatment (HDT) of algal biocrude. In addition, the Solar Energy Retained in Fuel (SERF) using HT technologies is calculated and compared with benchmark biofuel. Lastly, the Life Cycle Assessment (LCA) discusses the limitation of the current state of art as well as introduction to new potential input categories to obtain a detailed environmental profile. Copyright © 2015 Elsevier Ltd. All rights reserved.

Database Integrity Monitoring for Synthetic Vision Systems Using Machine Vision and SHADE

NASA Technical Reports Server (NTRS)

Cooper, Eric G.; Young, Steven D.

2005-01-01

In an effort to increase situational awareness, the aviation industry is investigating technologies that allow pilots to visualize what is outside of the aircraft during periods of low-visibility. One of these technologies, referred to as Synthetic Vision Systems (SVS), provides the pilot with real-time computer-generated images of obstacles, terrain features, runways, and other aircraft regardless of weather conditions. To help ensure the integrity of such systems, methods of verifying the accuracy of synthetically-derived display elements using onboard remote sensing technologies are under investigation. One such method is based on a shadow detection and extraction (SHADE) algorithm that transforms computer-generated digital elevation data into a reference domain that enables direct comparison with radar measurements. This paper describes machine vision techniques for making this comparison and discusses preliminary results from application to actual flight data.

Modelling Single Tree Structure with Terrestrial Laser Scanner

NASA Astrophysics Data System (ADS)

Yurtseven, H.; Akgül, M.; Gülci, S.

2017-11-01

Recent technological developments, which has reliable accuracy and quality for all engineering works, such as remote sensing tools have wide range use in forestry applications. Last decade, sustainable use and management opportunities of forest resources are favorite topics. Thus, precision of obtained data plays an important role in evaluation of current status of forests' value. The use of aerial and terrestrial laser technology has more reliable and effective models to advance the appropriate natural resource management. This study investigates the use of terrestrial laser scanner (TLS) technology in forestry, and also the methodological data processing stages for tree volume extraction is explained. Z+F Imager 5010C TLS system was used for measure single tree information such as tree height, diameter of breast height, branch volume and canopy closure. In this context more detailed and accurate data can be obtained than conventional inventory sampling in forestry by using TLS systems. However the accuracy of obtained data is up to the experiences of TLS operator in the field. Number of scan stations and its positions are other important factors to reduce noise effect and accurate 3D modelling. The results indicated that the use of point cloud data to extract tree information for forestry applications are promising methodology for precision forestry.

Life cycle Greenhouse gas emissions of current Oil Sands Technologies: surface mining and in situ applications.

PubMed

Bergerson, Joule A; Kofoworola, Oyeshola; Charpentier, Alex D; Sleep, Sylvia; Maclean, Heather L

2012-07-17

Life cycle greenhouse gas (GHG) emissions associated with two major recovery and extraction processes currently utilized in Alberta's oil sands, surface mining and in situ, are quantified. Process modules are developed and integrated into a life cycle model-GHOST (GreenHouse gas emissions of current Oil Sands Technologies) developed in prior work. Recovery and extraction of bitumen through surface mining and in situ processes result in 3-9 and 9-16 g CO(2)eq/MJ bitumen, respectively; upgrading emissions are an additional 6-17 g CO(2)eq/MJ synthetic crude oil (SCO) (all results are on a HHV basis). Although a high degree of variability exists in well-to-wheel emissions due to differences in technologies employed, operating conditions, and product characteristics, the surface mining dilbit and the in situ SCO pathways have the lowest and highest emissions, 88 and 120 g CO(2)eq/MJ reformulated gasoline. Through the use of improved data obtained from operating oil sands projects, we present ranges of emissions that overlap with emissions in literature for conventional crude oil. An increased focus is recommended in policy discussions on understanding interproject variability of emissions of both oil sands and conventional crudes, as this has not been adequately represented in previous studies.

Extraction of High Molecular Weight DNA from Fungal Rust Spores for Long Read Sequencing.

PubMed

Schwessinger, Benjamin; Rathjen, John P

2017-01-01

Wheat rust fungi are complex organisms with a complete life cycle that involves two different host plants and five different spore types. During the asexual infection cycle on wheat, rusts produce massive amounts of dikaryotic urediniospores. These spores are dikaryotic (two nuclei) with each nucleus containing one haploid genome. This dikaryotic state is likely to contribute to their evolutionary success, making them some of the major wheat pathogens globally. Despite this, most published wheat rust genomes are highly fragmented and contain very little haplotype-specific sequence information. Current long-read sequencing technologies hold great promise to provide more contiguous and haplotype-phased genome assemblies. Long reads are able to span repetitive regions and phase structural differences between the haplomes. This increased genome resolution enables the identification of complex loci and the study of genome evolution beyond simple nucleotide polymorphisms. Long-read technologies require pure high molecular weight DNA as an input for sequencing. Here, we describe a DNA extraction protocol for rust spores that yields pure double-stranded DNA molecules with molecular weight of >50 kilo-base pairs (kbp). The isolated DNA is of sufficient purity for PacBio long-read sequencing, but may require additional purification for other sequencing technologies such as Nanopore and 10× Genomics.

Post-Fragmentation Whole Genome Amplification-Based Method

NASA Technical Reports Server (NTRS)

Benardini, James; LaDuc, Myron T.; Langmore, John

2011-01-01

This innovation is derived from a proprietary amplification scheme that is based upon random fragmentation of the genome into a series of short, overlapping templates. The resulting shorter DNA strands (<400 bp) constitute a library of DNA fragments with defined 3 and 5 termini. Specific primers to these termini are then used to isothermally amplify this library into potentially unlimited quantities that can be used immediately for multiple downstream applications including gel eletrophoresis, quantitative polymerase chain reaction (QPCR), comparative genomic hybridization microarray, SNP analysis, and sequencing. The standard reaction can be performed with minimal hands-on time, and can produce amplified DNA in as little as three hours. Post-fragmentation whole genome amplification-based technology provides a robust and accurate method of amplifying femtogram levels of starting material into microgram yields with no detectable allele bias. The amplified DNA also facilitates the preservation of samples (spacecraft samples) by amplifying scarce amounts of template DNA into microgram concentrations in just a few hours. Based on further optimization of this technology, this could be a feasible technology to use in sample preservation for potential future sample return missions. The research and technology development described here can be pivotal in dealing with backward/forward biological contamination from planetary missions. Such efforts rely heavily on an increasing understanding of the burden and diversity of microorganisms present on spacecraft surfaces throughout assembly and testing. The development and implementation of these technologies could significantly improve the comprehensiveness and resolving power of spacecraft-associated microbial population censuses, and are important to the continued evolution and advancement of planetary protection capabilities. Current molecular procedures for assaying spacecraft-associated microbial burden and diversity have inherent sample loss issues at practically every step, particularly nucleic acid extraction. In engineering a molecular means of amplifying nucleic acids directly from single cells in their native state within the sample matrix, this innovation has circumvented entirely the need for DNA extraction regimes in the sample processing scheme.

Implicit prosody mining based on the human eye image capture technology

NASA Astrophysics Data System (ADS)

Gao, Pei-pei; Liu, Feng

2013-08-01

The technology of eye tracker has become the main methods of analyzing the recognition issues in human-computer interaction. Human eye image capture is the key problem of the eye tracking. Based on further research, a new human-computer interaction method introduced to enrich the form of speech synthetic. We propose a method of Implicit Prosody mining based on the human eye image capture technology to extract the parameters from the image of human eyes when reading, control and drive prosody generation in speech synthesis, and establish prosodic model with high simulation accuracy. Duration model is key issues for prosody generation. For the duration model, this paper put forward a new idea for obtaining gaze duration of eyes when reading based on the eye image capture technology, and synchronous controlling this duration and pronunciation duration in speech synthesis. The movement of human eyes during reading is a comprehensive multi-factor interactive process, such as gaze, twitching and backsight. Therefore, how to extract the appropriate information from the image of human eyes need to be considered and the gaze regularity of eyes need to be obtained as references of modeling. Based on the analysis of current three kinds of eye movement control model and the characteristics of the Implicit Prosody reading, relative independence between speech processing system of text and eye movement control system was discussed. It was proved that under the same text familiarity condition, gaze duration of eyes when reading and internal voice pronunciation duration are synchronous. The eye gaze duration model based on the Chinese language level prosodic structure was presented to change previous methods of machine learning and probability forecasting, obtain readers' real internal reading rhythm and to synthesize voice with personalized rhythm. This research will enrich human-computer interactive form, and will be practical significance and application prospect in terms of disabled assisted speech interaction. Experiments show that Implicit Prosody mining based on the human eye image capture technology makes the synthesized speech has more flexible expressions.

Factors influencing acceptance of technology for aging in place: a systematic review.

PubMed

Peek, Sebastiaan T M; Wouters, Eveline J M; van Hoof, Joost; Luijkx, Katrien G; Boeije, Hennie R; Vrijhoef, Hubertus J M

2014-04-01

To provide an overview of factors influencing the acceptance of electronic technologies that support aging in place by community-dwelling older adults. Since technology acceptance factors fluctuate over time, a distinction was made between factors in the pre-implementation stage and factors in the post-implementation stage. A systematic review of mixed studies. Seven major scientific databases (including MEDLINE, Scopus and CINAHL) were searched. Inclusion criteria were as follows: (1) original and peer-reviewed research, (2) qualitative, quantitative or mixed methods research, (3) research in which participants are community-dwelling older adults aged 60 years or older, and (4) research aimed at investigating factors that influence the intention to use or the actual use of electronic technology for aging in place. Three researchers each read the articles and extracted factors. Sixteen out of 2841 articles were included. Most articles investigated acceptance of technology that enhances safety or provides social interaction. The majority of data was based on qualitative research investigating factors in the pre-implementation stage. Acceptance in this stage is influenced by 27 factors, divided into six themes: concerns regarding technology (e.g., high cost, privacy implications and usability factors); expected benefits of technology (e.g., increased safety and perceived usefulness); need for technology (e.g., perceived need and subjective health status); alternatives to technology (e.g., help by family or spouse), social influence (e.g., influence of family, friends and professional caregivers); and characteristics of older adults (e.g., desire to age in place). When comparing these results to qualitative results on post-implementation acceptance, our analysis showed that some factors are persistent while new factors also emerge. Quantitative results showed that a small number of variables have a significant influence in the pre-implementation stage. Fourteen out of the sixteen included articles did not use an existing technology acceptance framework or model. Acceptance of technology in the pre-implementation stage is influenced by multiple factors. However, post-implementation research on technology acceptance by community-dwelling older adults is scarce and most of the factors in this review have not been tested by using quantitative methods. Further research is needed to determine if and how the factors in this review are interrelated, and how they relate to existing models of technology acceptance. Copyright © 2014 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

[The research on separating and extracting overlapping spectral feature lines in LIBS using damped least squares method].

PubMed

Wang, Yin; Zhao, Nan-jing; Liu, Wen-qing; Yu, Yang; Fang, Li; Meng, De-shuo; Hu, Li; Zhang, Da-hai; Ma, Min-jun; Xiao, Xue; Wang, Yu; Liu, Jian-guo

2015-02-01

In recent years, the technology of laser induced breakdown spectroscopy has been developed rapidly. As one kind of new material composition detection technology, laser induced breakdown spectroscopy can simultaneously detect multi elements fast and simply without any complex sample preparation and realize field, in-situ material composition detection of the sample to be tested. This kind of technology is very promising in many fields. It is very important to separate, fit and extract spectral feature lines in laser induced breakdown spectroscopy, which is the cornerstone of spectral feature recognition and subsequent elements concentrations inversion research. In order to realize effective separation, fitting and extraction of spectral feature lines in laser induced breakdown spectroscopy, the original parameters for spectral lines fitting before iteration were analyzed and determined. The spectral feature line of' chromium (Cr I : 427.480 nm) in fly ash gathered from a coal-fired power station, which was overlapped with another line(FeI: 427.176 nm), was separated from the other one and extracted by using damped least squares method. Based on Gauss-Newton iteration, damped least squares method adds damping factor to step and adjust step length dynamically according to the feedback information after each iteration, in order to prevent the iteration from diverging and make sure that the iteration could converge fast. Damped least squares method helps to obtain better results of separating, fitting and extracting spectral feature lines and give more accurate intensity values of these spectral feature lines: The spectral feature lines of chromium in samples which contain different concentrations of chromium were separated and extracted. And then, the intensity values of corresponding spectral lines were given by using damped least squares method and least squares method separately. The calibration curves were plotted, which showed the relationship between spectral line intensity values and chromium concentrations in different samples. And then their respective linear correlations were compared. The experimental results showed that the linear correlation of the intensity values of spectral feature lines and the concentrations of chromium in different samples, which was obtained by damped least squares method, was better than that one obtained by least squares method. And therefore, damped least squares method was stable, reliable and suitable for separating, fitting and extracting spectral feature lines in laser induced breakdown spectroscopy.

Geologic considerations in underground coal mining system design

NASA Technical Reports Server (NTRS)

Camilli, F. A.; Maynard, D. P.; Mangolds, A.; Harris, J.

1981-01-01

Geologic characteristics of coal resources which may impact new extraction technologies are identified and described to aid system designers and planners in their task of designing advanced coal extraction systems for the central Appalachian region. These geologic conditions are then organized into a matrix identified as the baseline mine concept. A sample region, eastern Kentucy is analyzed using both the developed baseline mine concept and the traditional geologic investigative approach.