Automotive Body Repair. Performance Objectives. Basic Course.

ERIC Educational Resources Information Center

Lang, Thomas

Several intermediate performance objectives and corresponding criterion measures are listed for each of 15 terminal objectives for a basic automotive body repair and refinishing course. The materials were developed for a two-semester (2 hours daily) course for organized classroom and shop experiences designed to enable the student to develop…

Service Station Attendant. Performance Objectives. Basic Course.

ERIC Educational Resources Information Center

Davis, John

Several intermediate performance objectives and corresponding criterion measures are listed for each of 24 terminal objectives for a basic secondary level service station attendant course. The materials were developed for a two-semester course (2 and 3 hours daily). The specialized classroom and shop experiences are designed to enable the student…

Welding. Performance Objectives. Intermediate Course.

ERIC Educational Resources Information Center

Vincent, Kenneth

Several intermediate performance objectives and corresponding criterion measures are listed for each of nine terminal objectives for an intermediate welding course. The materials were developed for a 36-week (3 hours daily) course designed to prepare the student for employment in the field of welding. Electric welding and specialized (TIG & MIG)…

Welding. Performance Objectives. Basic Course.

ERIC Educational Resources Information Center

Vincent, Kenneth

Several intermediate performance objectives and corresponding criterion measures are listed for each of eight terminal objectives for a basic welding course. The materials were developed for a 36-week (2 hours daily) course developed to teach the fundamentals of welding shop work, to become familiar with the operation of the welding shop…

Masonry. Performance Objectives. Intermediate Course.

ERIC Educational Resources Information Center

Thompson, Moses

Several intermediate performance objectives and corresponding criterion measures are listed for each of 13 terminal objectives for an intermediate masonry course. These materials, developed for a two-semester (3 hours daily) course, are designed to provide the student with the skills and knowledge necessary for entry level employment in the field…

Diesel Mechanics. Performance Objectives. Intermediate Course.

ERIC Educational Resources Information Center

Tidwell, Joseph

Several intermediate performance objectives and corresponding criterion measures are listed for each of six terminal objectives for an intermediate diesel mechanics course (two semesters, 3 hours daily) designed for high school students who upon completion would be ready for an on-the-job training experience in diesel service and repair. Through…

Carpentry. Performance Objectives. Basic Course.

ERIC Educational Resources Information Center

Downing, C. L.; Adcox, John W., Jr.

Several intermediate performance objectives and corresponding criterion measures are listed for each of 12 terminal objectives in this course guide in basic carpentry. The guide is designed to prepare persons for initial employment, or to upgrade or retrain persons already employed, or to provide the apprenticeship related course work necessary to…

Business Machine Maintenance. Performance Objectives. Basic Course.

ERIC Educational Resources Information Center

McMinn, Robert

Several intermediate performance objectives and corresponding criterion measures are listed for each of 25 terminal objectives presented in this guide for a basic business machine maintenance course at the secondary level. (For the intermediate course guide see CE 010 948.) The materials were developed for a two-semester (2 hour daily) course…

Cabinetmaking. Performance Objectives. Basic Course.

ERIC Educational Resources Information Center

Harvey, Bill

Several intermediate performance objectives and corresponding criterion measures are listed for each of 15 terminal objectives for a high school basic cabinetmaking course. The materials were developed for a two-semester (2 hours daily) course designed to develop and implement a well-grounded knowledge of the fundamentals of all phases of planning…

Machine Shop. Performance Objectives. Basic Course.

ERIC Educational Resources Information Center

Hilton, Arthur; Lambert, George

Several intermediate performance objectives and corresponding criterion measures are listed for each of 13 terminal objectives for a high school basic machine shop course. The materials were developed for a 36-week course (2 hours daily) designed to enable students to become familiar with the operation of machine shop equipment, to become familiar…

Metals. Industrial Arts. Performance Objectives, Junior High School.

ERIC Educational Resources Information Center

Bunch, Edwood; And Others

Several intermediate performance objectives and corresponding criterion measures are listed for a metals course for seventh, eighth, and ninth grade students. The seventh grade section includes 13 terminal objectives for a 9-week course and provides exploratory units in bench metals and sheet metals. Industrial materials and processes receive…

Channel and terminal description of the ACTS mobile terminal

NASA Technical Reports Server (NTRS)

Abbe, B. S.; Agan, M. J.; Girardey, C. C.; Jedrey, T. C.

1994-01-01

The Advanced Communications Technology Satellite (ACTS) Mobile Terminal (AMT) is a proof-of-concept K/Ka-band mobile satellite communications terminal under development by NASA at JPL. Currently the AMT is undergoing systems integration and testing in preparation for a July 1993 ACTS launch and the subsequent commencement of mobile experiments in the fall of 1993. The AMT objectives are presented, followed by a discussion of the AMT communications channel and the mobile terminal's design and performance.

Channel and terminal description of the ACTS mobile terminal

NASA Technical Reports Server (NTRS)

Abbe, B. S.; Agan, M. J.; Girardey, C. C.; Jedrey, T. C.

1993-01-01

The Advanced Communications Technology Satellite (ACTS) Mobile Terminal (AMT) is a proof-of-concept K/Ka-band mobile satellite communications terminal under development by NASA at JPL. Currently the AMT is undergoing system integration and test in preparation for a July 1993 ACTS launch and the subsequent commencement of mobile experiments in the fall of 1993. The AMT objectives are presented followed by a discussion of the AMT communications channel and mobile terminal design and performance.

Building Maintenance. Performance Objectives. Basic Course.

ERIC Educational Resources Information Center

Taylor, Ernest

Several intermediate performance objectives and corresponding criterion measures are listed for each of the 13 terminal objectives for a basic high school building maintenance course (the first year of a 3-year program). The materials were developed for a 36-week course (2 hours daily) designed to enable 10th grade students to develop competencies…

Commercial and Advertising Art. Performance Objectives. Basic Course.

ERIC Educational Resources Information Center

Atkinson, Floyd

Several intermediate performance objectives and corresponding criterion measures are listed for each of 12 terminal objectives for a basic commercial and advertising art course. The materials were developed for a two-semester (2 hours daily) course to enable tenth, eleventh, and twelfth grade students to develop competencies in the care and use of…

Parts Marketing. A Student Learning Guide.

ERIC Educational Resources Information Center

Ridge Vocational-Technical Center, Winter Haven, FL.

This learning guide is a self-instructional packet for one task identified as essential for performance on an entry-level job in parts marketing. The guide is based on a terminal performance objective (task) and two enabling objectives. For each enabling objective, some or all of these materials may be presented: learning steps (outline of student…

Gasoline Engine Mechanics. Performance Objectives. Basic Course.

ERIC Educational Resources Information Center

Jones, Marion

Several intermediate performance objectives and corresponding criterion measures are listed for each of five terminal objectives presented in this curriculum guide for a basic gasoline engine mechanics course at the secondary level. (For the intermediate course guide see CE 010 946.) The materials were developed for a two semester (2 hours daily)…

Diesel Mechanics. Performance Objectives. Basic Course.

ERIC Educational Resources Information Center

Tidwell, Joseph

Several intermediate performance objectives and corresponding criterion measures are listed for each of 12 terminal objectives for a basic diesel mechanics course. The course is designed as a two-semester (2 hour daily) course for 10th graders interested in being diesel service and repair mechanics; it would serve as the first year of a 3-year…

Custodial Services and Building Maint: Performance Objectives.

ERIC Educational Resources Information Center

Downing, Charles; And Others

Several intermediate performance objectives and corresponding criterion measures are listed for each of 14 terminal objectives for high school custodial service and building maintenance course (the third year of a 3-year program). The materials were developed for a 36-week course (3 hours daily) designed to prepare 12th graders with entry level…

Welding. Student Learning Guides.

ERIC Educational Resources Information Center

Ridge Vocational-Technical Center, Winter Haven, FL.

These 23 learning guides are self-instructional packets for 23 tasks identified as essential for performance on an entry-level job in welding. Each guide is based on a terminal performance objective (task) and 1-4 enabling objectives. For each enabling objective, some or all of these materials may be presented: learning steps (outline of student…

Plumbing and Pipefitting. Student Learning Guides.

ERIC Educational Resources Information Center

Ridge Vocational-Technical Center, Winter Haven, FL.

These 32 learning guides are self-instructional packets for 32 tasks identified as essential for performance on an entry-level job in plumbing and pipefitting. Each guide is based on a terminal performance objective (task) and 1-4 enabling objectives. For each enabling objective, some or all of these materials may be presented: learning steps…

Clothing Production. Student Learning Guides.

ERIC Educational Resources Information Center

Ridge Vocational-Technical Center, Winter Haven, FL.

These 59 learning guides are self-instructional packets for 59 tasks identified as essential for performance on an entry-level job in clothing production. Each guide is based on a terminal performance objective (task) and 2-5 enabling objectives. For each enabling objective, some or all of these materials may be presented: learning steps (outline…

Personal Career Orientation. Performance Objectives. Criterion Measures. Home Economics.

ERIC Educational Resources Information Center

Allen, Alveta; And Others

Several intermediate performance objectives and corresponding criterion measures are listed for each of six terminal objectives for a personal career orientation course for seventh grade students. This 6- to 9-week course is designed to acquaint the student with personal qualities and characteristics necessary for success in the world of work.…

Home Economics. Exploration of Clothing Management, Production and Service Occupations. Performance Objectives. Criterion Measures.

ERIC Educational Resources Information Center

Duval County School Board, Jacksonville, FL.

Several intermediate performance objectives and corresponding criterion measures are presented for each of five terminal objectives for a 12- to 18-week course designed to provide students in grades 8 or 9 with opportunities to explore a broad range of clothing management, production, and service occupations. The course was designed to provide…

Consumer Education--Home Economics. Performance Objectives. Criterion Measures. Home Economics.

ERIC Educational Resources Information Center

Duval County School Board, Jacksonville, FL.

Several intermediate performance objectives and corresponding criterion measures are listed for each of six terminal objectives for an 18-week consumer education-home economics course for 10th, 11th, and 12th grade students. Purposes listed for the course are to develop an understanding of the American market system, and how the individual affects…

Commercial Foods and Culinary Arts. Student Learning Guides.

ERIC Educational Resources Information Center

Ridge Vocational-Technical Center, Winter Haven, FL.

These 13 learning guides are self-instructional packets for 13 tasks identified as essential for performance on an entry-level job in commercial foods and culinary arts. Each guide is based on a terminal performance objective (task) and 1-4 enabling objectives. For each enabling objective, some or all of these materials may be presented: learning…

Ohio Agriscience Lesson Plans.

ERIC Educational Resources Information Center

Sommers, Robert D., II, Comp.; Waidelich, William D., Comp.

This document, which is intended for Ohio agriculture teachers, contains lesson plans for an eight-unit competency-based course in agriscience. Each lesson plan contains some or all of the following items: (1) unit title; (2) competency/terminal performance objective; (3) competency builders/pupil performance objectives; (4) list of applied…

Closing the Reference Interview: Implications for Policy and Practice.

ERIC Educational Resources Information Center

Nolan, Christopher W.

1992-01-01

Discusses reasons why patrons or librarians terminate the reference interview, including the content of the interview, interpersonal dynamics, and institutional or policy factors. Goals and objectives of the person terminating the interview are considered, and guidelines for policy development and performance improvement are offered. (30…

American Industries. Junior Hi. Pre-Vocational. Power and Transportation.

ERIC Educational Resources Information Center

Goldsbury, Paul; And Others

Several intermediate performance objectives and corresponding criterion measures are listed for each of 10 terminal objectives in this junior high school power and transportation course guide. Each objective also includes learning steps and suggestions for supplementary instructional aids. The overall focus is on the concepts of industrial…

Determination of thermal properties of commercial Ni-MH cells

NASA Astrophysics Data System (ADS)

Darcy, Eric C.

1994-02-01

The test objectives were to evaluate the electrical and thermal performance of commercial Ni-MH cells, evaluate the effectiveness of commercial charge control circuits, assess the abuse tolerance of these cells, and correlate performance and abuse tolerances to cell design via disassembly. Design objectives were to determine which cell designs are most suitable for scale-up and to guide the design of future shuttle and space station based battery chargers. Results, displayed in viewgraph format, include: reflex charging with ICS circuit resulted in premature charge termination; Ni-MH cells appear very tolerant to overcharge at low rates; Enstore's charger is more electrically and thermally efficient at high rates; and Ni-MH cycles much more efficiently than Ni-Cd with the delta-V/delta-t termination.

Airborne Visible Laser Optical Communications (AVLOC) experiment

NASA Technical Reports Server (NTRS)

1974-01-01

A series of optical communication experiments between a high altitude aircraft at 18.3 km (60,000 ft) and a ground station were conducted by NASA from summer 1972 through winter 1973. The basic system was an optical tracker and transmitter located in each terminal. The aircraft transceiver consisted of a 5-mW HeNe laser transmitter with a 30-megabit modulator. The ground station beacon was an argon laser operating at 488 nm. A separate pulsed laser radar was used for initial acquisition. The objective of the experiment was to obtain engineering data on the precision tracking and communication system performance at both terminals. Atmospheric effects on the system performance was also an experiment objective. The system description, engineering analysis, testing, and flight results are discussed.

Determination of thermal properties of commercial Ni-MH cells

NASA Technical Reports Server (NTRS)

Darcy, Eric C.

1994-01-01

The test objectives were to evaluate the electrical and thermal performance of commercial Ni-MH cells, evaluate the effectiveness of commercial charge control circuits, assess the abuse tolerance of these cells, and correlate performance and abuse tolerances to cell design via disassembly. Design objectives were to determine which cell designs are most suitable for scale-up and to guide the design of future shuttle and space station based battery chargers. Results, displayed in viewgraph format, include: reflex charging with ICS circuit resulted in premature charge termination; Ni-MH cells appear very tolerant to overcharge at low rates; Enstore's charger is more electrically and thermally efficient at high rates; and Ni-MH cycles much more efficiently than Ni-Cd with the delta-V/delta-t termination.

Appliance Services. Intermediate Course. Career Education.

ERIC Educational Resources Information Center

Killough, Joseph

Several intermediate performance objectives and corresponding criterion measures are listed for each of 16 terminal objectives for an intermediate appliance repair course. The materials were developed for a 36-week course (3 hours daily) covering the areas of refrigeration, maintenance, repair, and troubleshooting of refrigerators and air…

Assessment of body-powered upper limb prostheses by able-bodied subjects, using the Box and Blocks Test and the Nine-Hole Peg Test.

PubMed

Haverkate, Liz; Smit, Gerwin; Plettenburg, Dick H

2016-02-01

The functional performance of currently available body-powered prostheses is unknown. The goal of this study was to objectively assess and compare the functional performance of three commonly used body-powered upper limb terminal devices. Experimental trial. A total of 21 able-bodied subjects (n = 21, age = 22 ± 2) tested three different terminal devices: TRS voluntary closing Hook Grip 2S, Otto Bock voluntary opening hand and Hosmer Model 5XA hook, using a prosthesis simulator. All subjects used each terminal device nine times in two functional tests: the Nine-Hole Peg Test and the Box and Blocks Test. Significant differences were found between the different terminal devices and their scores on the Nine-Hole Peg Test and the Box and Blocks Test. The Hosmer hook scored best in both tests. The TRS Hook Grip 2S scored second best. The Otto Bock hand showed the lowest scores. This study is a first step in the comparison of functional performances of body-powered prostheses. The data can be used as a reference value, to assess the performance of a terminal device or an amputee. The measured scores enable the comparison of the performance of a prosthesis user and his or her terminal device relative to standard scores. © The International Society for Prosthetics and Orthotics 2014.

Radio and Television Servicing. Intermediate Course.

ERIC Educational Resources Information Center

Campbell, Guy; And Others

Several intermediate performance objectives and corresponding criterion measures are listed for each of 32 terminal objectives for an intermediate (second year) radio/TV servicing course. This 1-year course (3 hours daily) was designed to provide the student with the basic skills and knowledges necessary for entry level employment in the Radio/TV…

Masonry. Basic Course. Career Education.

ERIC Educational Resources Information Center

Muldrow, Oliver

Several intermediate performance objectives and corresponding criterion measures are listed for each of 22 terminal objectives for a basic masonry course. The materials were developed for a 36-week course (2 hours daily). Organized subject matter and practical experiences are designed to prepare students for entry level skills in the masonry…

General Mechanical Trades: A Curriculum Guide. Revised Edition.

ERIC Educational Resources Information Center

Henderson, W. Charles; And Others

The guide contains six sections, each consisting of one or more units of general mechanical trades instruction. The sections cover: safety and tools, measuring and blueprint reading, gas welding, arc welding, small engines, and metal work. Each unit includes performance objectives stated as terminal objectives, indicating the subject matter to be…

Appliance Services. Basic Course. Career Education.

ERIC Educational Resources Information Center

Killough, Joseph

Several intermediate performance objectives and corresponding criterion measures are listed for each of 25 terminal objectives for a basic appliance repair course. The materials were developed for a 36-week course (2 hours daily) designed to enable the student to be well-grounded in the fundamentals of electricity as well as applied electricity.…

Respiratory Therapists' Experiences and Attitudes Regarding Terminal Extubations and End-of-Life Care.

PubMed

Grandhige, Anjali P; Timmer, Marjorie; O'Neill, Michael J; Binney, Zachary O; Quest, Tammie E

2016-07-01

Respiratory therapists (RTs) routinely care for patients with life-limiting illnesses and in some hospitals are responsible for terminal extubations. Data on how such experiences affect RTs are scarce. The objective of this work was to survey RTs at 2 academic medical centers about their experiences caring for patients with terminal extubations. An online survey was distributed to the hospitals' RTs. Survey data included demographics and experiences with end-of-life care and terminal extubations. The survey was derived from previously published questionnaires plus input from hospital RT leaders. Sixty-five of 173 RTs (37.6%) responded. Of these, 42.4% were ≥50 y old, and 62.7% were female. 20.3% had ≤5 y experience; 52.5% had ≥16 y. 93.8% self-reported being involved in at least one terminal extubation; of those, 36.1% reported performing ≥20. Nearly half (47.5%) wanted to be involved in family meetings discussing terminal extubations, but just 6.6% were frequently involved. Only 32.3% felt that they received adequate education regarding terminal illness in RT school; 32.3% reported gathering this knowledge while working. 60.0% wanted more formal education around terminal patient care. 27.9% reported sometimes being uncomfortable with performing a terminal extubation; most of these rarely felt that they had the option not to perform the extubation. RTs are rarely involved in end-of-life discussions despite a desire to be, and they experience situations that generate discomfort. There is demand for more formal RT training around care for terminal patients. Clinical protocols that involve RTs in meetings before ventilator withdrawal should be considered. Copyright © 2016 by Daedalus Enterprises.

A longitudinal study evaluating the effects of interferon-alpha therapy on cognitive and psychiatric function in adults with chronic hepatitis C

PubMed Central

Huckans, Marilyn; Fuller, Bret; Wheaton, Viva; Jaehnert, Sarah; Ellis, Carilyn; Kolessar, Michael; Kriz, Daniel; Anderson, Jeanne Renee; Berggren, Kristin; Olavarria, Hannah; Sasaki, Anna W.; Chang, Michael; Flora, Kenneth D.; Loftis, Jennifer M.

2015-01-01

Objective To prospectively evaluate for changes in objective cognitive performance (attention, memory, and executive function) and psychiatric symptom severity (depression, anxiety, fatigue, and pain) in patients before, during and after interferon-alpha based therapy (IFN) for chronic hepatitis C virus infection (HCV). Methods 33 HCV+ adults were evaluated two months before IFN initiation (baseline), three months into IFN, and six months following IFN termination (IFN+ Group). 31 HCV+ adults who did not undergo IFN therapy were evaluated at baseline and six months later (IFN− Group). At each evaluation, participants completed the Neuropsychological Assessment Battery (NAB) Attention, Memory and Executive Functions Modules, the Beck Depression Inventory, Second Edition (BDI), Generalized Anxiety Disorder Inventory (GADI), Fatigue Severity Scale (FSS), and Brief Pain Inventory (BPI). Results Compared with the IFN−Group, the IFN+ Group experienced significantly (p < 0.050) increased symptoms of depression, anxiety, fatigue and pain during IFN therapy relative to baseline. In the IFN+ Group, psychiatric symptoms generally returned to baseline levels following IFN termination. Sustained viral response was associated with significantly lower depression and fatigue. No significant changes in cognitive performance were observed. Conclusions During IFN, patients with HCV evidence significantly increased psychiatric symptoms, including symptoms of depression, anxiety, fatigue and pain. These psychiatric symptoms are generally short-term and remit following IFN termination, with increased benefit if viral clearance is achieved. However, IFN is not associated with significant declines in objective cognitive performance during or following IFN. PMID:25219976

Decriminalisation of abortion performed by qualified health practitioners under the Abortion Law Reform Act 2008 (Vic).

PubMed

Mendelson, Danuta

2012-06-01

In 2008, the Victorian Parliament enacted the Abortion Law Reform Act 2008 (Vic) and amended the Crimes Act 1958 (Vic) to decriminalise terminations of pregnancy while making it a criminal offence for unqualified persons to carry out such procedures. The reform legislation has imposed a civil regulatory regime on the management of abortions, and has stipulated particular statutory duties of care for registered qualified health care practitioners who have conscientious objections to terminations of pregnancy. The background to, and the structure of, this novel statutory regime is examined, with a focus on conscientious objection clauses and liability in the tort of negligence and the tort of breach of statutory duty.

The Iowa Disinfection Cleaning Project: Opportunities, Successes, and Challenges of a Structured Intervention Program in 56 Hospitals.

PubMed

Carling, Philip; Herwaldt, Loreen A

2017-08-01

OBJECTIVE A diverse group of hospitals in Iowa implemented a program to objectively evaluate and improve the thoroughness of disinfection cleaning of near-patient surfaces. Administrative benefits of, challenges of, and impediments to the program were also evaluated. METHODS We conducted a prospective, quasi-experimental pre-/postintervention trial to improve the thoroughness of terminal room disinfection cleaning. Infection preventionists utilized an objective cleaning performance monitoring system (DAZO) to evaluate the thoroughness of disinfection cleaning (TDC) expressed as a proportion of objects confirmed to have been cleaned (numerator) to objects to be cleaned per hospital policy (denominator)×100. Data analysis, educational interventions, and objective performance feedback were modeled on previously published studies using the same monitoring tool. Programmatic analysis utilized unstructured and structured information from participants irrespective of whether they participated in the process improvement aspects to the program. RESULTS Initially, the overall TDC was 61% in 56 hospitals. Hospitals completing 1 or 2 feedback cycles improved their TDC percentages significantly (P90% for at least 38 months. A survey of infection preventionists found that lack of time and staff turnover were the most common reasons for terminating the study early. CONCLUSION The study confirmed that hospitals using this program can improve their TDC percentages significantly. Hospitals must invest resources to improve cleaning and to sustain their gains. Infect Control Hosp Epidemiol 2017;38:960-965.

Motion coherence affects human perception and pursuit similarly.

PubMed

Beutter, B R; Stone, L S

2000-01-01

Pursuit and perception both require accurate information about the motion of objects. Recovering the motion of objects by integrating the motion of their components is a difficult visual task. Successful integration produces coherent global object motion, while a failure to integrate leaves the incoherent local motions of the components unlinked. We compared the ability of perception and pursuit to perform motion integration by measuring direction judgments and the concomitant eye-movement responses to line-figure parallelograms moving behind stationary rectangular apertures. The apertures were constructed such that only the line segments corresponding to the parallelogram's sides were visible; thus, recovering global motion required the integration of the local segment motion. We investigated several potential motion-integration rules by using stimuli with different object, vector-average, and line-segment terminator-motion directions. We used an oculometric decision rule to directly compare direction discrimination for pursuit and perception. For visible apertures, the percept was a coherent object, and both the pursuit and perceptual performance were close to the object-motion prediction. For invisible apertures, the percept was incoherently moving segments, and both the pursuit and perceptual performance were close to the terminator-motion prediction. Furthermore, both psychometric and oculometric direction thresholds were much higher for invisible apertures than for visible apertures. We constructed a model in which both perception and pursuit are driven by a shared motion-processing stage, with perception having an additional input from an independent static-processing stage. Model simulations were consistent with our perceptual and oculomotor data. Based on these results, we propose the use of pursuit as an objective and continuous measure of perceptual coherence. Our results support the view that pursuit and perception share a common motion-integration stage, perhaps within areas MT or MST.

Motion coherence affects human perception and pursuit similarly

NASA Technical Reports Server (NTRS)

Beutter, B. R.; Stone, L. S.

2000-01-01

Pursuit and perception both require accurate information about the motion of objects. Recovering the motion of objects by integrating the motion of their components is a difficult visual task. Successful integration produces coherent global object motion, while a failure to integrate leaves the incoherent local motions of the components unlinked. We compared the ability of perception and pursuit to perform motion integration by measuring direction judgments and the concomitant eye-movement responses to line-figure parallelograms moving behind stationary rectangular apertures. The apertures were constructed such that only the line segments corresponding to the parallelogram's sides were visible; thus, recovering global motion required the integration of the local segment motion. We investigated several potential motion-integration rules by using stimuli with different object, vector-average, and line-segment terminator-motion directions. We used an oculometric decision rule to directly compare direction discrimination for pursuit and perception. For visible apertures, the percept was a coherent object, and both the pursuit and perceptual performance were close to the object-motion prediction. For invisible apertures, the percept was incoherently moving segments, and both the pursuit and perceptual performance were close to the terminator-motion prediction. Furthermore, both psychometric and oculometric direction thresholds were much higher for invisible apertures than for visible apertures. We constructed a model in which both perception and pursuit are driven by a shared motion-processing stage, with perception having an additional input from an independent static-processing stage. Model simulations were consistent with our perceptual and oculomotor data. Based on these results, we propose the use of pursuit as an objective and continuous measure of perceptual coherence. Our results support the view that pursuit and perception share a common motion-integration stage, perhaps within areas MT or MST.

State Regulatory Enforcement and Nursing Home Termination from the Medicare and Medicaid Programs

PubMed Central

Li, Yue; Harrington, Charlene; Spector, William D; Mukamel, Dana B

2010-01-01

Objectives Nursing homes certified by the Medicare and/or Medicaid program are subject to federally mandated and state-enforced quality and safety standards. We examined the relationship between state quality enforcement and nursing home terminations from the two programs. Study Design Using data from a survey of state licensure and certification agencies and other secondary databases, we performed bivariate and multivariate analyses on the strength of state quality regulation in 2005, and nursing home voluntary terminations (decisions made by the facility) or involuntary terminations (imposed by the state) in 2006–2007. Principal Findings Involuntary terminations were rarely imposed by state regulators, while voluntary terminations were relatively more common (2.16 percent in 2006–2007) and varied considerably across states. After controlling for facility, market, and state covariates, nursing homes in states implementing stronger quality enforcement were more likely to voluntarily terminate from the Medicare and Medicaid programs (odds ratio=1.53, p=.018). Conclusions Although involuntary nursing home terminations occurred rarely in most states, nursing homes in states with stronger quality regulations tend to voluntarily exit the publicly financed market. Because of the consequences of voluntary terminations on patient care and access, state regulators need to consider the effects of increased enforcement on both enhanced quality and the costs of termination. PMID:20819106

War Termination: Dreaming of the End and the Ultimate Triumph

DTIC Science & Technology

2004-05-17

and unstructured, art and science . To realize national strategic objectives and develop a triumphant peace, operational commanders must shun the...itself, war termination is both political and military, structured and unstructured, art and science . To realize national strategic objectives and...termination is political and military, structured and unstructured, art and science . By applying elements of operational art to war termination and

Professional Teacher Education Module Series. Assess Student Performance: Knowledge, Module D-2 of Category D--Instructional Evaluation.

ERIC Educational Resources Information Center

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

This second in a series of six learning modules on instructional evaluation is designed to give secondary and postsecondary vocational teachers help in assessing student performance as it relates to knowledge of the facts, data, related information, and procedures taught in their vocational courses. The terminal objective for the module is to…

Development of a multi-media crew-training program for the Terminal Configured Vehicle Mission Simulator

NASA Technical Reports Server (NTRS)

Houck, J. A.; Markos, A. T.

1980-01-01

This paper describes the work being done at the National Aeronautics and Space Administration's (NASA) Langley Research Center on the development of a multi-media crew-training program for the Terminal Configured Vehicle (TCV) Mission Simulator. Brief descriptions of the goals and objectives of the TCV Program and of the TCV Mission Simulator are presented. A detailed description of the training program is provided along with a description of the performance of the first group of four commercial pilots to be qualified in the TCV Mission Simulator.

Development of a multi-media crew-training program for the terminal configured vehicle mission simulator

NASA Technical Reports Server (NTRS)

Rhouck, J. A.; Markos, A. T.

1980-01-01

This paper describes the work being done at the National Aeronautics and Space Administration's (NASA) Langley Research Center on the development of a multi-media crew-training program for the Terminal Configured Vehicle (TCV) Mission Simulator. Brief descriptions of the goals and objectives of the TCV Program and of the TCV Mission Simulator are presented. A detailed description of the training program is provided along with a description of the performance of the first group of four commercial pilots to be qualified in the TCV Mission Simulator.

AIBS Education Review, Vol. 2, No. 4.

ERIC Educational Resources Information Center

Creager, Joan G., Ed.

This issue contains articles on experiences gained in the construction of terminal performance objectives for introductory biology courses, the impact of audiotutorial instruction on faculty load and departmental operating levels, an experiment designed to improve the teaching of biology in large enrollment introductory courses, a minicourse on…

Terminal velocity of a shuttlecock in vertical fall

NASA Astrophysics Data System (ADS)

Peastrel, Mark; Lynch, Rosemary; Armenti, Angelo

1980-07-01

We have performed a straightforward vertical fall experiment for a case where the effects of air resistance are important and directly measurable. Using a commonly available badminton shuttlecock, a tape measure, and a millisecond timer, the times required for the shuttlecock to fall given distances (up to almost ten meters) were accurately measured. The experiment was performed in an open stairwell. The experimental data was compared to the predictions of several models. The best fit was obtained with the model which assumes a resistive force quadratic in the instantaneous speed of the falling object. This model was fitted to the experimental data enabling us to predict the terminal velocity of the shuttlecock (6.80 m/sec). The results indicate that, starting from rest, the vertically falling shuttlecock achieves 99% of its terminal velocity in 1.84 sec, after falling 9.2 m. The relative ease in collecting the data, as well as the excellent agreement with theory, make this an ideal experiment for use in physics courses at a variety of levels.

Guidelines for Conducting a Training Effectiveness Evaluation (TEE). Volume 1. TEE Evaluator’s Handbook

DTIC Science & Technology

1985-02-01

by drawing prerequisite lines, the relationships between all subordinate skills and knowledges and the terminal objective. Thus, for purposes of...functions, tasks, or skills below it, rate the relationship of the performances shown in the superordinate box to those in the subordinate boxes...A useful format for displaying performance relationships between team functions and subordinate tasks or communication and coordination skills

Performance evaluation method of electric energy data acquire system based on combination of subjective and objective weights

NASA Astrophysics Data System (ADS)

Gao, Chen; Ding, Zhongan; Deng, Bofa; Yan, Shengteng

2017-10-01

According to the characteristics of electric energy data acquire system (EEDAS), considering the availability of each index data and the connection between the index integrity, establishing the performance evaluation index system of electric energy data acquire system from three aspects as master station system, communication channel, terminal equipment. To determine the comprehensive weight of each index based on triangular fuzzy number analytic hierarchy process with entropy weight method, and both subjective preference and objective attribute are taken into consideration, thus realize the performance comprehensive evaluation more reasonable and reliable. Example analysis shows that, by combination with analytic hierarchy process (AHP) and triangle fuzzy numbers (TFN) to establish comprehensive index evaluation system based on entropy method, the evaluation results not only convenient and practical, but also more objective and accurate.

Inhibited solid propellant composition containing beryllium hydride

NASA Technical Reports Server (NTRS)

Thompson, W. W. (Inventor)

1978-01-01

An object of this invention is to provide a composition of beryllium hydride and carboxy-terminated polybutadiene which is stable. Another object of this invention is to provide a method for inhibiting the reactivity of beryllium hydride toward carboxy-terminated polybutadiene. It was found that a small amount of lecithin inhibits the reaction of beryllium hydride with the acid groups in carboxy terminated polybutadiene.

Analysis of Nursing Curriculum and Course Competencies.

ERIC Educational Resources Information Center

Trani, G. M.

The objectives of this study were to relate the competencies of the Nursing Program at Delaware County Community College to national morbidity statistics and to recommend curriculum changes based on this analysis. Existing terminal objectives of the program and each nursing module were compared with college-wide terminal objectives, overlap was…

Advanced Respite Care: Medically Challenged. Teacher Edition. Respite Care Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This curriculum guide is designed to help teachers to provide advanced-level training for care providers who want to work with individuals who are chronically or terminally ill and require specialized care. The curriculum contains seven units. Each of the instructional units includes some or all of these basic components: performance objectives,…

Atmospheric-Fade-Tolerant Tracking and Pointing in Wireless Optical Communication

NASA Technical Reports Server (NTRS)

Ortiz, Gerardo; Lee, Shinhak

2003-01-01

An acquisition, tracking, and pointing (ATP) system, under development at the time of reporting the information for this article, is intended to enable a terminal in a free-space optical communication system to continue to aim its transmitting laser beam toward a receiver at a remote terminal when the laser beacon signal from the remote terminal temporarily fades or drops out of sight altogether. Such fades and dropouts can be caused by adverse atmospheric conditions (e.g., rain or clouds). They can also occur when intervening objects block the line of sight between terminals as a result of motions of those objects or of either or both terminals

GTEX: An expert system for diagnosing faults in satellite ground stations

NASA Technical Reports Server (NTRS)

Schlegelmilch, Richard F.; Durkin, John; Petrik, Edward J.

1991-01-01

A proof of concept expert system called Ground Terminal Expert (GTEX) was developed at The University of Akron in collaboration with NASA Lewis Research Center. The objective of GTEX is to aid in diagnosing data faults occurring with a digital ground terminal. This strategy can also be applied to the Very Small Aperture Terminal (VSAT) technology. An expert system which detects and diagnoses faults would enhance the performance of the VSAT by improving reliability and reducing maintenance time. GTEX is capable of detecting faults, isolating the cause and recommending appropriate actions. Isolation of faults is completed to board-level modules. A graphical user interface provides control and a medium where data can be requested and cryptic information logically displayed. Interaction with GTEX consists of user responses and input from data files. The use of data files provides a method of simulating dynamic interaction between the digital ground terminal and the expert system. GTEX as described is capable of both improving reliability and reducing the time required for necessary maintenance.

GTEX: An expert system for diagnosing faults in satellite ground stations

NASA Astrophysics Data System (ADS)

Schlegelmilch, Richard F.; Durkin, John; Petrik, Edward J.

1991-11-01

A proof of concept expert system called Ground Terminal Expert (GTEX) was developed at The University of Akron in collaboration with NASA Lewis Research Center. The objective of GTEX is to aid in diagnosing data faults occurring with a digital ground terminal. This strategy can also be applied to the Very Small Aperture Terminal (VSAT) technology. An expert system which detects and diagnoses faults would enhance the performance of the VSAT by improving reliability and reducing maintenance time. GTEX is capable of detecting faults, isolating the cause and recommending appropriate actions. Isolation of faults is completed to board-level modules. A graphical user interface provides control and a medium where data can be requested and cryptic information logically displayed. Interaction with GTEX consists of user responses and input from data files. The use of data files provides a method of simulating dynamic interaction between the digital ground terminal and the expert system. GTEX as described is capable of both improving reliability and reducing the time required for necessary maintenance.

Traffic sharing algorithms for hybrid mobile networks

NASA Technical Reports Server (NTRS)

Arcand, S.; Murthy, K. M. S.; Hafez, R.

1995-01-01

In a hybrid (terrestrial + satellite) mobile personal communications networks environment, a large size satellite footprint (supercell) overlays on a large number of smaller size, contiguous terrestrial cells. We assume that the users have either a terrestrial only single mode terminal (SMT) or a terrestrial/satellite dual mode terminal (DMT) and the ratio of DMT to the total terminals is defined gamma. It is assumed that the call assignments to and handovers between terrestrial cells and satellite supercells take place in a dynamic fashion when necessary. The objectives of this paper are twofold, (1) to propose and define a class of traffic sharing algorithms to manage terrestrial and satellite network resources efficiently by handling call handovers dynamically, and (2) to analyze and evaluate the algorithms by maximizing the traffic load handling capability (defined in erl/cell) over a wide range of terminal ratios (gamma) given an acceptable range of blocking probabilities. Two of the algorithms (G & S) in the proposed class perform extremely well for a wide range of gamma.

Construction of a new, objective prognostic score for terminally ill cancer patients: a multicenter study.

PubMed

Suh, Sang-Yeon; Choi, Youn Seon; Shim, Jae Yong; Kim, Young Sung; Yeom, Chang Hwan; Kim, Daeyoung; Park, Shin Ae; Kim, Sooa; Seo, Ji Yeon; Kim, Su Hyun; Kim, Daegyeun; Choi, Sung-Eun; Ahn, Hong-Yup

2010-02-01

The goal of this study was to develop a new, objective prognostic score (OPS) for terminally ill cancer patients based on an integrated model that includes novel objective prognostic factors. A multicenter study of 209 terminally ill cancer patients from six training hospitals in Korea were prospectively followed until death. The Cox proportional hazard model was used to adjust for the influence of clinical and laboratory variables on survival time. The OPS was calculated from the sum of partial scores obtained from seven significant predictors determined by the final model. The partial score was based on the hazard ratio of each predictor. The accuracy of the OPS was evaluated. The overall median survival was 26 days. On the multivariate analysis, reduced oral intake, resting dyspnea, low performance status, leukocytosis, elevated bilirubin, elevated creatinine, and elevated lactate dehydrogenase (LDH) were identified as poor prognostic factors. The range of OPS was from 0.0 to 7.0. For the above cutoff point of 3.0, the 3-week prediction sensitivity was 74.7%, the specificity was 76.5%, and the overall accuracy was 75.5%. We developed the new OPS, without clinician's survival estimates but including a new prognostic factor (LDH). This new instrument demonstrated accurate prediction of the 3-week survival. The OPS had acceptable accuracy in this study population (training set). Further validation is required on an independent population (testing set).

Influence of Seeding Ratio, Planting Date, and Termination Date on Rye-Hairy Vetch Cover Crop Mixture Performance under Organic Management

PubMed Central

Lawson, Andrew; Cogger, Craig; Bary, Andy; Fortuna, Ann-Marie

2015-01-01

Cover crop benefits include nitrogen accumulation and retention, weed suppression, organic matter maintenance, and reduced erosion. Organic farmers need region-specific information on winter cover crop performance to effectively integrate cover crops into their crop rotations. Our research objective was to compare cover crop seeding mixtures, planting dates, and termination dates on performance of rye (Secale cereale L.) and hairy vetch (Vicia villosa Roth) monocultures and mixtures in the maritime Pacific Northwest USA. The study included four seed mixtures (100% hairy vetch, 25% rye-75% hairy vetch, 50% rye-50% hairy vetch, and 100% rye by seed weight), two planting dates, and two termination dates, using a split-split plot design with four replications over six years. Measurements included winter ground cover; stand composition; cover crop biomass, N concentration, and N uptake; and June soil NO3 --N. Rye planted in mid-September and terminated in late April averaged 5.1 Mg ha-1 biomass, whereas mixtures averaged 4.1 Mg ha-1 and hairy vetch 2.3 Mg ha-1. Delaying planting by 2.5 weeks reduced average winter ground cover by 65%, biomass by 50%, and cover crop N accumulation by 40%. Similar reductions in biomass and N accumulation occurred for late March termination, compared with late April termination. Mixtures had less annual biomass variability than rye. Mixtures accumulated 103 kg ha-1 N and had mean C:N ratio <17:1 when planted in mid-September and terminated in late April. June soil NO3 --N (0 to 30 cm depth) averaged 62 kg ha-1 for rye, 97 kg ha-1 for the mixtures, and 119 kg ha-1 for hairy vetch. Weeds comprised less of the mixtures biomass (20% weeds by weight at termination) compared with the monocultures (29%). Cover crop mixtures provided a balance between biomass accumulation and N concentration, more consistent biomass over the six-year study, and were more effective at reducing winter weeds compared with monocultures. PMID:26080008

Influence of Seeding Ratio, Planting Date, and Termination Date on Rye-Hairy Vetch Cover Crop Mixture Performance under Organic Management.

PubMed

Lawson, Andrew; Cogger, Craig; Bary, Andy; Fortuna, Ann-Marie

2015-01-01

Cover crop benefits include nitrogen accumulation and retention, weed suppression, organic matter maintenance, and reduced erosion. Organic farmers need region-specific information on winter cover crop performance to effectively integrate cover crops into their crop rotations. Our research objective was to compare cover crop seeding mixtures, planting dates, and termination dates on performance of rye (Secale cereale L.) and hairy vetch (Vicia villosa Roth) monocultures and mixtures in the maritime Pacific Northwest USA. The study included four seed mixtures (100% hairy vetch, 25% rye-75% hairy vetch, 50% rye-50% hairy vetch, and 100% rye by seed weight), two planting dates, and two termination dates, using a split-split plot design with four replications over six years. Measurements included winter ground cover; stand composition; cover crop biomass, N concentration, and N uptake; and June soil NO3(-)-N. Rye planted in mid-September and terminated in late April averaged 5.1 Mg ha(-1) biomass, whereas mixtures averaged 4.1 Mg ha(-1) and hairy vetch 2.3 Mg ha(-1). Delaying planting by 2.5 weeks reduced average winter ground cover by 65%, biomass by 50%, and cover crop N accumulation by 40%. Similar reductions in biomass and N accumulation occurred for late March termination, compared with late April termination. Mixtures had less annual biomass variability than rye. Mixtures accumulated 103 kg ha(-1) N and had mean C:N ratio <17:1 when planted in mid-September and terminated in late April. June soil NO3(-)-N (0 to 30 cm depth) averaged 62 kg ha(-1) for rye, 97 kg ha(-1) for the mixtures, and 119 kg ha(-1) for hairy vetch. Weeds comprised less of the mixtures biomass (20% weeds by weight at termination) compared with the monocultures (29%). Cover crop mixtures provided a balance between biomass accumulation and N concentration, more consistent biomass over the six-year study, and were more effective at reducing winter weeds compared with monocultures.

AMPA experimental communications systems

NASA Technical Reports Server (NTRS)

Beckerman, D.; Fass, S.; Keon, T.; Sielman, P.

1982-01-01

The program was conducted to demonstrate the satellite communication advantages of Adaptive Phased Array Technology. A laboratory based experiment was designed and implemented to demonstrate a low earth orbit satellite communications system. Using a 32 element, L-band phased array augmented with 4 sets of weights (2 for reception and 2 for transmission) a high speed digital processing system and operating against multiple user terminals and interferers, the AMPA system demonstrated: communications with austere user terminals, frequency reuse, communications in the face of interference, and geolocation. The program and experiment objectives are described, the system hardware and software/firmware are defined, and the test performed and the resultant test data are presented.

FAA Air Traffic Control Operations Concepts. Volume 2. ACF/ACCC (Area Control Facility/Area Control Computer Complex) Terminal and En Route Controllers. Change 1

DTIC Science & Technology

1988-07-29

VOLff2) 6 July 19837 A-74 A1.5.6 MONITORING NON-CONTROLLED OBJECTS AIM, 7 OIHERS REPORT AIRSPACEJ FIRST 10 DETECT INTRUSION IradR’SIoN BY NON-CON’TROLLED 1...1988 Volume II: ACF/ACCC Terminal and En Route Controllers (ClIG 1) 6 . Porliming Organization Code 7 . Author(s) 8. Performing Organization Report No...MANEUVER SYSTEM GENERATES ABSORPT ION PREVIOUSLY PREPARED RECEIVED MANEUVER FOR A FLIGHT CLEAPANCEI D0T/FAA/AP-47-01 (VOLt2) 6 July 1987 A- 7 A,1.O

Requirements for Flight Testing Automated Terminal Service

DOT National Transportation Integrated Search

1977-05-01

This report describes requirements for the flight tests of the baseline Automated Terminals Service (ATS) system. The overall objective of the flight test program is to evaluate the feasibility of the ATS concept. Within this objective there are two ...

Advances In Engineering Science, Volume 2.

DTIC Science & Technology

1976-11-01

UNDRAINED CLAY BEHAVIOR .... ............ .. 95 Jean-Herve Prevost and Kaare H~eg THEORY OF ORTHODONTIC MOTIONS...compo- nents at a lower level are terminal nodes of a tree. The bracketed numbers on the right hand side of the terminating nodes are the number of...primitive data objects in each instance of the defined object. The bracketed numbers on the right hand side of the non-terminal nodes in the tree are the

A Study of Job Demands and Curriculum Development in Agricultural Training Related to the Muskegon County Wastewater Management System. Final Report. Volume III. Student Terminal Performance Objectives and Instructional Modules.

ERIC Educational Resources Information Center

Fisher, Harold S.; And Others

This is the third volume of a four-volume report of a research project designed to (1) identify job needs for agricultural occupations which will result from the Muskegon County Wastewater Management System and perform a task analysis on each occupation, (2) develop instructional modules and determine their place in either high school or 2-year…

Losing a father all over again: the termination of an analysis of an adolescent boy suffering from father loss.

PubMed

Sugarman, Alan

2010-08-01

Criteria for beginning and conducting the termination phase of psychoanalysis have provoked debate and confusion from the early days of psychoanalysis. Gabbard (2009) has recently pointed to the field's tendency to cling to idealized versions of these criteria as a way to deal with disagreements. The situation becomes more complicated for child and adolescent psychoanalysts because their patients are in the midst of a developmental process at the very time they are engaged in a psychoanalytic process. The termination phase of an adolescent male suffering from father loss is presented in depth in order to provide clinical data toward further consideration of the vexing questions surrounding termination in psychoanalysis. His termination is used to examine the relative importance of losing the analyst as a transference object as against a developmental object; the meaning of action during termination; the complicating role of trauma vis-à-vis termination; and the importance of the post-termination phase of analysis. It is suggested that his termination phase demonstrates that a "good enough" termination involves the development of a self-analyzing capacity that continues to evolve and develop after termination.

[Music in human terminality: the family members' conceptions].

PubMed

Sales, Catarina Aparecida; da Silva, Vladimir Araujo; Pilger, Calíope; Marcon, Sonia Silva

2011-03-01

This qualitative study was performed using the multiple case study method and Heidegger's existential phenomenology for data analysis. The objective was to understand how family members perceive the influence of musical experiences on the physical and mental health of a relative living with a terminal illness. Participants were seven individuals belonging to two families. Data collection was performed through interviews and observation from May to June 2009. Results showed that using music while providing care to beings living with cancer can provide well-being to patients as well as their caregivers. Considering the deficit of leisure and the monotony of the home environment, using music contemplates the philosophical and humanitarian precepts of palliative care, thus being characterized as a complementary resource to nursing care, as besides being a communication resource, it improves the interpersonal relationship between patients and their families.

Light microscopic image analysis system to quantify immunoreactive terminal area apposed to nerve cells.

PubMed

Wu, L C; D'Amelio, F; Fox, R A; Polyakov, I; Daunton, N G

1997-06-06

The present report describes a desktop computer-based method for the quantitative assessment of the area occupied by immunoreactive terminals in close apposition to nerve cells in relation to the perimeter of the cell soma. This method is based on Fast Fourier Transform (FFT) routines incorporated in NIH-Image public domain software. Pyramidal cells of layer V of the somatosensory cortex outlined by GABA immunolabeled terminals were chosen for our analysis. A Leitz Diaplan light microscope was employed for the visualization of the sections. A Sierra Scientific Model 4030 CCD camera was used to capture the images into a Macintosh Centris 650 computer. After preprocessing, filtering was performed on the power spectrum in the frequency domain produced by the FFT operation. An inverse FFT with filter procedure was employed to restore the images to the spatial domain. Pasting of the original image to the transformed one using a Boolean logic operation called 'AND'ing produced an image with the terminals enhanced. This procedure allowed the creation of a binary image using a well-defined threshold of 128. Thus, the terminal area appears in black against a white background. This methodology provides an objective means of measurement of area by counting the total number of pixels occupied by immunoreactive terminals in light microscopic sections in which the difficulties of labeling intensity, size, shape and numerical density of terminals are avoided.

Light microscopic image analysis system to quantify immunoreactive terminal area apposed to nerve cells

NASA Technical Reports Server (NTRS)

Wu, L. C.; D'Amelio, F.; Fox, R. A.; Polyakov, I.; Daunton, N. G.

1997-01-01

The present report describes a desktop computer-based method for the quantitative assessment of the area occupied by immunoreactive terminals in close apposition to nerve cells in relation to the perimeter of the cell soma. This method is based on Fast Fourier Transform (FFT) routines incorporated in NIH-Image public domain software. Pyramidal cells of layer V of the somatosensory cortex outlined by GABA immunolabeled terminals were chosen for our analysis. A Leitz Diaplan light microscope was employed for the visualization of the sections. A Sierra Scientific Model 4030 CCD camera was used to capture the images into a Macintosh Centris 650 computer. After preprocessing, filtering was performed on the power spectrum in the frequency domain produced by the FFT operation. An inverse FFT with filter procedure was employed to restore the images to the spatial domain. Pasting of the original image to the transformed one using a Boolean logic operation called 'AND'ing produced an image with the terminals enhanced. This procedure allowed the creation of a binary image using a well-defined threshold of 128. Thus, the terminal area appears in black against a white background. This methodology provides an objective means of measurement of area by counting the total number of pixels occupied by immunoreactive terminals in light microscopic sections in which the difficulties of labeling intensity, size, shape and numerical density of terminals are avoided.

Frequency stabilization for mobile satellite terminals via LORAN

NASA Technical Reports Server (NTRS)

Ernst, Gregory J.; Kee, Steven M.; Marquart, Robert C.

1990-01-01

Digital satellite communication systems require careful management of frequency stability. Historically, frequency stability has been accomplished by continuously powered, high cost, high performance reference oscillators. Today's low cost mobile satellite communication equipment must operate under wide ranging environmental conditions, stabilize quickly after application of power, and provide adequate performance margin to overcome RF link impairments unique to the land mobile environment. Methods for frequency stabilization in land mobile applications must meet these objectives without incurring excessive performance degradation. A frequency stabilization scheme utilizing the LORAN (Long Range Navigation) system is presented.

Does Individual Gambling Behavior Vary across Gambling Venues with Differing Numbers of Terminals? An Empirical Real-World Study using Player Account Data.

PubMed

Sagoe, Dominic; Pallesen, Ståle; Griffiths, Mark D; Mentzoni, Rune A; Leino, Tony

2018-01-01

Research examining gambling behavior via experiments, self-report, and/or observation presents many methodical challenges particularly in relation to objectivity. However, the use of player account-based gambling data provides purely objective data. Based on this real-world data, the primary aim of the present study was to examine gambling behavior in gambling venues with different numbers of gambling terminals (i.e., venues with one terminal; 2-5 terminals; 6-10 terminals; 11-16 terminals). Player account-based gambling data aggregated over a year (2015) amounting to 153,379 observations within 93,034 individual gamblers (males = 74%; mean age = 44.1, SD = 16.4 years) were analyzed. Gambling frequency was highest in venues with 2-5 terminals (54.5%) and lowest in venues with 11-16 terminals (1.6%). Approximately half of the sample (52.5%) gambled in only one venue category, with the majority (81.5%) preferring venues with 2-5 terminals present. Only 0.8% of the sample gambled in all four venue categories. Compared to venues with one terminal, venues with two or more terminals were associated with gamblers placing more bets, and spending more time and money per session. However, gamblers had higher losses (albeit small) in venues with one terminal compared to venues with 2-5 terminals. No differences in net outcome were found between venues with one terminal and those with 6-10 and 11-16 terminals. Overall, the present study demonstrates that in the natural gambling environment, gambling behavior is reinforced in venues with multiple terminals.

Joint Terminal Attack Controllers Sensors and Lasers Modernization

DTIC Science & Technology

2012-09-01

and Evaluation Activity MCSC Marine Corps Systems Command MCT Marine Corps Task MCTL Marine Corps Task List MEMS MicroElectroMechanical Systems...functional relationship of the key performance requirements was associated to Marine Corps Tasks ( MCT ), Critical Operational Issues (COIs...to an accomplishment of mission objectives and achievement of desired results [5]. All COIs are linked to a MCT , which are provided within the

Pediatric Critical Care Transport as a Conduit to Terminal Extubation at Home: A Case Series

PubMed Central

Noje, Corina; Bernier, Meghan L.; Costabile, Philomena M.; Klein, Bruce L.; Kudchadkar, Sapna R.

2016-01-01

Objective To present our single-center’s experience with three palliative critical care transports home from the pediatric intensive care unit (PICU) for terminal extubation. Design, Setting, Patients All cases were identified from our institutional Pediatric Transport database. Patients in the case series were terminally ill children unable to separate from mechanical ventilation in the PICU, who were transported home between January 1, 2012 and December 31, 2014 for terminal extubation and end-of-life care according to their families’ wishes. Interventions, Measurements, Main Results The rate of palliative care transports home for terminal extubation during the study period was 2.6 per 100 deaths. The patients were 7 months, 6 years, and 18 years old and had complex chronic conditions. The transfer process was protocolized. The families were approached by the PICU staff during multidisciplinary goals-of-care meetings. Parental expectations were clarified and home hospice care was arranged pre-transfer. All transports were performed by our pediatric critical care transport team, and all terminal extubations were performed by physicians. All patients had unstable medical conditions and urgent needs for transport to comply with the families’ wishes for withdrawal of life-support and death at home. As such, all three cases presented similar logistical challenges, including establishing do-not-resuscitate status pre-transport, having limited time to organize the transport, and coordinating home palliative care services with available community resources. Conclusions Though a relatively infrequent practice in pediatric critical care, transport home for terminal extubation represents a feasible alternative for families seeking out-of-hospital end-of-life care for their critically ill technology-dependent children. Our single-center experience supports the need for development of formal programs for end-of-life critical care transports to include patient screening tools, palliative care home discharge algorithms, transport protocols, and resource utilization and cost analyses. PMID:27801708

Terminal Behavioral Objectives for Teaching Clinical Toxicology to Clinical Pharmacists

ERIC Educational Resources Information Center

Veltri, Joseph C.; And Others

1976-01-01

As a first step in the development of a competency-based clinical toxicology clerkship, a set of terminal behavioral objectives were developed that reflect the anticipated role that clinical pharmacists should play as part of the clinical toxicology team. The evaluation approaches used at the University of Utah are presented. (LBH)

Flight experiments to improve terminal area operations

NASA Technical Reports Server (NTRS)

Salmirs, S.; Morello, S. A.

1978-01-01

A brief description is given of the objectives and activities of the terminal configured vehicle (TCV) program and of some of the airborne facilities. A short analysis of some particular problems in CTOL operations in the terminal area is also presented to show how the program's technical objectives are related to the defined problems. The test aircraft was flown both manually and automatically with manual monitoring over paths including 130 deg intercepts and 2.0 km and 0.8 km finals. Some statistical data are presented from these and other flight profiles designed to address specific terminal area problems. An overview is presented of research studies receiving emphasis in the next biennium and their application to the terminal area. A description of work undertaken to study the addition of adjacent traffic information to present map displays is also given.

Flight experiments to improve terminal area operations

NASA Technical Reports Server (NTRS)

Salmirs, S.; Morello, S. A.

1978-01-01

A brief description is given of the objectives and activities of the terminal configured vehicle (TCV) program and of some of the airborne facilities. A short analysis of some particular problems of CTOL operations in the terminal area is also presented to show how the program's technical objectives are related to the defined problems. The test aircraft was flown both manually and automatically with manual monitoring over paths including 130 deg intercepts and 2.0 km (1.1. n. mi.) and 0.8 km (0.44 n. mi.) finals. Some statistical data are presented from these and other flight profiles designed to address specific terminal in the next biennium and their application to the terminal area. A description of work being undertaken to study the addition of adjacent traffic information to present map displays is also given.

Does Individual Gambling Behavior Vary across Gambling Venues with Differing Numbers of Terminals? An Empirical Real-World Study using Player Account Data

PubMed Central

Sagoe, Dominic; Pallesen, Ståle; Griffiths, Mark D.; Mentzoni, Rune A.; Leino, Tony

2018-01-01

Research examining gambling behavior via experiments, self-report, and/or observation presents many methodical challenges particularly in relation to objectivity. However, the use of player account-based gambling data provides purely objective data. Based on this real-world data, the primary aim of the present study was to examine gambling behavior in gambling venues with different numbers of gambling terminals (i.e., venues with one terminal; 2–5 terminals; 6–10 terminals; 11–16 terminals). Player account-based gambling data aggregated over a year (2015) amounting to 153,379 observations within 93,034 individual gamblers (males = 74%; mean age = 44.1, SD = 16.4 years) were analyzed. Gambling frequency was highest in venues with 2–5 terminals (54.5%) and lowest in venues with 11–16 terminals (1.6%). Approximately half of the sample (52.5%) gambled in only one venue category, with the majority (81.5%) preferring venues with 2–5 terminals present. Only 0.8% of the sample gambled in all four venue categories. Compared to venues with one terminal, venues with two or more terminals were associated with gamblers placing more bets, and spending more time and money per session. However, gamblers had higher losses (albeit small) in venues with one terminal compared to venues with 2–5 terminals. No differences in net outcome were found between venues with one terminal and those with 6–10 and 11–16 terminals. Overall, the present study demonstrates that in the natural gambling environment, gambling behavior is reinforced in venues with multiple terminals. PMID:29503626

Discrete event simulation model for external yard choice of import container terminal in a port buffer area

NASA Astrophysics Data System (ADS)

Rusgiyarto, Ferry; Sjafruddin, Ade; Frazila, Russ Bona; Suprayogi

2017-06-01

Increasing container traffic and land acquisition problem for terminal expansion leads to usage of external yard in a port buffer area. This condition influenced the terminal performance because a road which connects the terminal and the external yard was also used by non-container traffic. Location choice problem considered to solve this condition, but the previous research has not taken account a stochastic condition of container arrival rate and service time yet. Bi-level programming framework was used to find optimum location configuration. In the lower-level, there was a problem to construct the equation, which correlated the terminal operation and the road due to different time cycle equilibrium. Container moves from the quay to a terminal gate in a daily unit of time, meanwhile, it moves from the terminal gate to the external yard through the road in a minute unit of time. If the equation formulated in hourly unit equilibrium, it cannot catch up the container movement characteristics in the terminal. Meanwhile, if the equation formulated in daily unit equilibrium, it cannot catch up the road traffic movement characteristics in the road. This problem can be addressed using simulation model. Discrete Event Simulation Model was used to simulate import container flow processes in the container terminal and external yard. Optimum location configuration in the upper-level was the combinatorial problem, which was solved by Full Enumeration approach. The objective function of the external yard location model was to minimize user transport cost (or time) and to maximize operator benefit. Numerical experiment was run for the scenario assumption of two container handling ways, three external yards, and thirty-day simulation periods. Jakarta International Container Terminal (JICT) container characteristics data was referred for the simulation. Based on five runs which were 5, 10, 15, 20, and 30 repetitions, operation one of three available external yards (external yard - 3) was the optimum result. Apparently, the model confirmed the hypothesis that there was an optimum configuration of the external yard. Nevertheless, the model needs detail elaboration related to the objective function and the optimization constraint. It requires detail validation, in term of service time value, distribution pattern, and arrival rate in each unit server modeled in the next step of the research. The model gave unique and relatively consistent value of each run. It was indicated that the method has a chance to solve the research problem.

Tubular Crystals and Helical Arrays: Structural Determination of HIV-1 Capsid Assemblies Using Iterative Helical Real-Space Reconstruction

PubMed Central

Zhang, Peijun; Meng, Xin; Zhao, Gongpu

2013-01-01

Helical structures are important in many different life forms and are well-suited for structural studies by cryo-EM. A unique feature of helical objects is that a single projection image contains all the views needed to perform a three-dimensional (3D) crystallographic reconstruction. Here, we use HIV-1 capsid assemblies to illustrate the detailed approaches to obtain 3D density maps from helical objects. Mature HIV-1 particles contain a conical- or tubular-shaped capsid that encloses the viral RNA genome and performs essential functions in the virus life cycle. The capsid is composed of capsid protein (CA) oligomers which are helically arranged on the surface. The N-terminal domain (NTD) of CA is connected to its C-terminal domain (CTD) through a flexible hinge. Structural analysis of two- and three-dimensional crystals provided molecular models of the capsid protein (CA) and its oligomer forms. We determined the 3D density map of helically assembled HIV-1 CA hexamers at 16 Å resolution using an iterative helical real-space reconstruction method. Docking of atomic models of CA-NTD and CA-CTD dimer into the electron density map indicated that the CTD dimer interface is retained in the assembled CA. Furthermore, molecular docking revealed an additional, novel CTD trimer interface. PMID:23132072

Application of VSC-HVDC with Shunt Connected SMES for Compensation of Power Fluctuation

NASA Astrophysics Data System (ADS)

Linn, Zarchi; Kakigano, Hiroaki; Miura, Yushi; Ise, Toshifumi

This paper describes the application of VSC-HVDC (High Voltage DC Transmission using Voltage Source Converter) with shunt connected SMES (Superconducting Magnetic Energy Storage) for compensation of power fluctuation caused by fluctuating power source such as photovoltaics and wind turbines. The objectives of this proposed system is to smooth out fluctuating power in one terminal side of HVDC in order to avoid causing power system instability and frequency deviation by absorbing or providing power according to the system requirement while another terminal side power is fluctuated. The shunt connected SMES charges and discharges the energy to and from the dc side and it compensates required power of fluctuation to obtain constant power flow in one terminal side of VSC-HVDC system. This system configuration has ability for power system stabilization in the case of power fluctuation from natural energy source. PSCAD/EMTDC simulation is used to evaluate the performance of applied system configuration and control method.

Feed intake and efficiency of F1 lambs

USDA-ARS?s Scientific Manuscript database

Objective estimates of feed efficiency for progeny of terminal-sire breeds of sheep are needed to improve the value of market lambs. Because recent terminal-sire breed-comparison data are lacking, we determined effects of terminal-sire breed on feed efficiency of F1 lambs. Each year for 3 yr, Columb...

Economic selection index development for Beefmaster cattle I: Terminal breeding objective.

PubMed

Ochsner, K P; MacNeil, M D; Lewis, R M; Spangler, M L

2017-03-01

The objective of this study was to develop an economic selection index for Beefmaster cattle in a terminal production system where bulls are mated to mature cows with all resulting progeny harvested. National average prices from 2010 to 2014 were used to establish income and expenses for the system. Phenotypic and genetic parameter values among the selection criteria and goal traits were obtained from literature. Economic values were estimated by simulating 100,000 animals and approximating the partial derivatives of the profit function by perturbing traits one at a time, by 1 unit, while holding the other traits constant at their respective means. Relative economic values (REV) for the terminal objective traits HCW, marbling score (MS), ribeye area (REA), 12th-rib fat (FAT), and feed intake (FI) were 91.29, 17.01, 8.38, -7.07, and -29.66, respectively. Consequently, improving the efficiency of beef production is expected to impact profitability greater than improving carcass merit alone. The accuracy of the index lies between 0.338 (phenotypic selection) and 0.503 (breeding values known without error). The application of this index would aid Beefmaster breeders in their sire selection decisions, facilitating genetic improvement for a terminal breeding objective.

36 CFR 51.48 - What happens to a right of preference in the event of termination of a concession contract for...

Code of Federal Regulations, 2010 CFR

2010-07-01

... its terms at any time for less than satisfactory performance or otherwise. If a concession contract is terminated for less than satisfactory performance or other breach, the terminated concessioner, even if... terminated a concession contract for less than satisfactory performance or other breach will not limit the...

Short-term blueberry-enriched diet prevents and reverses object recognition memory loss in aging rats.

PubMed

Malin, David H; Lee, David R; Goyarzu, Pilar; Chang, Yu-Hsuan; Ennis, Lalanya J; Beckett, Elizabeth; Shukitt-Hale, Barbara; Joseph, James A

2011-03-01

Previously, 4 mo of a blueberry-enriched (BB) antioxidant diet prevented impaired object recognition memory in aging rats. Experiment 1 determined whether 1- and 2-mo BB diets would have a similar effect and whether the benefits would disappear promptly after terminating the diets. Experiment 2 determined whether a 1-mo BB diet could subsequently reverse existing object memory impairment in aging rats. In experiment 1, Fischer-344 rats were maintained on an appropriate control diet or on 1 or 2 mo of the BB diet before testing object memory at 19 mo postnatally. In experiment 2, rats were tested for object recognition memory at 19 mo and again at 20 mo after 1 mo of maintenance on a 2% BB or control diet. In experiment 1, the control group performed no better than chance, whereas the 1- and 2-mo BB diet groups performed similarly and significantly better than controls. The 2-mo BB-diet group, but not the 1-mo group, maintained its performance over a subsequent month on a standard laboratory diet. In experiment 2, the 19-mo-old rats performed near chance. At 20 mo of age, the rats subsequently maintained on the BB diet significantly increased their object memory scores, whereas the control diet group exhibited a non-significant decline. The change in object memory scores differed significantly between the two diet groups. These results suggest that a considerable degree of age-related object memory decline can be prevented and reversed by brief maintenance on BB diets. Copyright © 2011 Elsevier Inc. All rights reserved.

Propagation-related AMT design aspects and supporting experiments

NASA Technical Reports Server (NTRS)

Dessouky, Khaled; Estabrook, Polly

1991-01-01

The ACTS Mobile Terminal (AMT) is presently being developed with the goal of significantly extending commercial satellite applications and their user base. A thorough knowledge of the Ka-band channel characteristics is essential to the proper design of a commercially viable system that efficiently utilizes the valuable resources. To date, only limited tests have been performed to characterize the Ka-band channel, and they have focused on the needs of fixed terminals. As part of the value of the AMT as a Ka-band test bed is its function as a vehicle through which tests specifically applicable to the mobile satellite communications can be performed. The exact propagation environment with the proper set of elevation angles, vehicle antenna gains and patterns, roadside shadowing, rain, and Doppler is encountered. The ability to measure all of the above, as well as correlate their effects with observed communication system performance, creates an invaluable opportunity to understand in depth Ka-band's potential in supporting mobile and personal communications. This paper discusses the propagation information required for system design, the setup with ACTS that will enable obtaining this information, and finally the types of experiments to be performed and data to be gathered by the AMT to meet this objective.

Intelligent nonsingular terminal sliding-mode control using MIMO Elman neural network for piezo-flexural nanopositioning stage.

PubMed

Lin, Faa-Jeng; Lee, Shih-Yang; Chou, Po-Huan

2012-12-01

The objective of this study is to develop an intelligent nonsingular terminal sliding-mode control (INTSMC) system using an Elman neural network (ENN) for the threedimensional motion control of a piezo-flexural nanopositioning stage (PFNS). First, the dynamic model of the PFNS is derived in detail. Then, to achieve robust, accurate trajectory-tracking performance, a nonsingular terminal sliding-mode control (NTSMC) system is proposed for the tracking of the reference contours. The steady-state response of the control system can be improved effectively because of the addition of the nonsingularity in the NTSMC. Moreover, to relax the requirements of the bounds and discard the switching function in NTSMC, an INTSMC system using a multi-input-multioutput (MIMO) ENN estimator is proposed to improve the control performance and robustness of the PFNS. The ENN estimator is proposed to estimate the hysteresis phenomenon and lumped uncertainty, including the system parameters and external disturbance of the PFNS online. Furthermore, the adaptive learning algorithms for the training of the parameters of the ENN online are derived using the Lyapunov stability theorem. In addition, two robust compensators are proposed to confront the minimum reconstructed errors in INTSMC. Finally, some experimental results for the tracking of various contours are given to demonstrate the validity of the proposed INTSMC system for PFNS.

Overview and Status of the Lunar Laser Communication Demonstration

NASA Technical Reports Server (NTRS)

Boroson, D. M.; Robinson, B. S.; Burianek, D. A.; Murphy, D. V.; Biswas, A.

2012-01-01

The Lunar Laser Communication Demonstration (LLCD), a project being undertaken by MIT Lincoln Laboratory, NASA's Goddard Space Flight Center, and the Jet Propulsion Laboratory, will be NASA's first attempt to demonstrate optical communications between a lunar orbiting spacecraft and Earth-based ground receivers. The LLCD space terminal will be flown on the Lunar Atmosphere and Dust Environment Explorer (LADEE) spacecraft, presently scheduled to launch in 2013. LLCD will demonstrate downlink optical communications at rates up to 620 Mbps, uplink optical communications at rates up to 20 Mbps, and two-way time-of-flight measurements with the potential to perform ranging with sub-centimeter accuracy. We describe the objectives of the LLCD program, key technologies employed in the space and ground terminals, and show the status of development of the several systems.

Palliative care for people with dementia in the terminal phase: a mixed-methods qualitative study to inform service development.

PubMed

van der Steen, Jenny T; Lemos Dekker, Natashe; Gijsberts, Marie-José H E; Vermeulen, Laura H; Mahler, Margje M; The, B Anne-Mei

2017-04-28

When entering the dying phase, the nature of physical, psychosocial and spiritual care needs of people with dementia and their families may change. Our objective was to understand what needs to be in place to develop optimal palliative care services for the terminal phase in the face of a small evidence base. In 2015-2016, we performed a mixed-methods qualitative study in which we (1) analysed the domains and recommendations from the European Association for Palliative Care (EAPC) dementia white paper and identified those with particular relevance for the terminal phase; (2) performed a series of focus group discussions with Dutch family caregivers of people with dementia in variable stages; (3) conducted interviews with experts involved in 15 special forms of terminal care for people with dementia in five countries. The terminal phase was defined as dying but because of the difficulty predicting it, we included advanced dementia. We initially analysed the three parts separately, followed by an integrated analysis of (1)-(3) to inform service development. (1) The EAPC domain of "avoiding overly aggressive, burdensome, or futile treatment" was regarded of particular relevance in the terminal phase, along with a number of recommendations that refer to providing of comfort. (2) Families preferred continuity in care and living arrangements. Despite a recognition that this was a time when they had complex support needs, they found it difficult to accept involvement of a large team of unfamiliar (professional) caregivers. Mostly, terminal care was preferred at the place of residence. (3) The expert interviews identified preferred, successful models in which a representative of a well-trained team has the time, authority and necessary expertise to provide care and education of staff and family to where people are and which ensure continuity of relationships with and around the patient. A mobile team that specializes in palliative care in dementia and supports professional and family caregivers is a promising model. Compared to transfer to a hospice in the last weeks or days, it has the potential to address the priorities of families and patients for continuity of care, relationships and specialist expertise.

Second Line of Defense Megaports Initiative Operational Testing and Evaluation Plan - Kingston Container Terminal, Port of Kingston, Jamaica

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deforest, Thomas J.; VanDyke, Damon S.

2012-03-01

Operational Testing and Evaluation Plan - Kingston Container Terminal, Port of Kingston, Jamaica was written for the Second Line of Defense Megaports Initiative. The purpose of the Operational Testing and Evaluation (OT&E) phase of the project is to prepare for turnover of the Megaports system supplied by U.S. Department of Energy/National Nuclear Security Administration (DOE/NNSA) located at the Kingston Container Terminal (KCT) of the Port of Kingston, Jamaica to the Government of Jamaica (GOJ). Activities conducted during the OT&E phase must demonstrate that the Megaports system can be operated effectively in real time by Jamaica Customs and KCT personnel tomore » the satisfaction of the DOE/NNSA. These activities will also determine if the Megaports system, as installed and accepted, is performing according to the Megaports Program objectives such that the system is capable of executing the mission of the Second Line of Defense Megaports Initiative. The OT&E phase of the project also provides an opportunity to consider potential improvements to the system and to take remedial action if performance deficiencies are identified during the course of evaluation. Changes to the system should be considered under an appropriate change-control process. DOE/NNSA will determine that OT&E is complete by examining whether the Megaports system is performing as intended and that the GOJ is fully capable of operating the system independently without continued onsite support from the U.S. team.« less

Prosthetic Jamming Terminal Device: A Case Study of Untethered Soft Robotics

PubMed Central

Amend, John; Farrell, Todd; Latour, Debra; Martinez, Carlos; Johansson, Jen; McNicoll, Anthony; Wartenberg, Marek; Naseef, Samuel; Hanson, William; Culley, William

2016-01-01

Abstract This article illuminates the major and often overlooked challenge of untethering soft robotic systems through the context of recent work, in which soft robotic gripper technology enabled by jamming of granular media was applied to a prosthetic jamming terminal device (PJTD). The PJTD's technical and market feasibility was evaluated in a pilot study with two upper-limb amputees. A PJTD prototype was tested against a commercial device (Motion Control electric terminal service with a one degree-of-freedom pinching mechanism) using two existing hand function tests: the first quantified the device's speed in picking and placing small blocks and the second evaluated a person's ability to perform activities of daily living (ADLs). The PJTD prototype performed slightly slower than its commercial counterpart in the first test. While both participants successfully completed all the ADLs with both devices in the second test, the commercial device scored marginally higher. Results suggested that PJTD can have potential benefits over existing terminal devices, such as providing the capability to firmly grasp tools due to the ability of PJTD to conform to arbitrary surfaces and reducing compensatory shoulder movements due to its axisymmetric design. Some downsides were that users reported fatigue while operating the PJTD, as most operations require pushing the PJTD against target objects to adequately conform to them. The greatest drawback for the PJTD is also a major roadblock preventing a number of soft robotic research projects from making an impact in real-world applications: pneumatic technology required for operating the PJTD is currently too large and heavy to enable compact untethered operation. PMID:28078196

28 CFR 51.64 - Bar to termination of coverage (bailout).

Code of Federal Regulations, 2011 CFR

2011-07-01

... ADMINISTRATION OF SECTION 5 OF THE VOTING RIGHTS ACT OF 1965, AS AMENDED Sanctions § 51.64 Bar to termination of coverage (bailout). (a) Section 4(a) of the Act sets out the requirements for the termination of coverage... under section 4(a)(1)(E) a section 5 objection to a submitted voting standard, practice, or procedure if...

28 CFR 51.64 - Bar to termination of coverage (bailout).

Code of Federal Regulations, 2010 CFR

2010-07-01

... ADMINISTRATION OF SECTION 5 OF THE VOTING RIGHTS ACT OF 1965, AS AMENDED Sanctions § 51.64 Bar to termination of coverage (bailout). (a) Section 4(a) of the Act sets out the requirements for the termination of coverage... under section 4(a)(1)(E) a section 5 objection to a submitted voting standard, practice, or procedure if...

Degenerative changes of the canine cervical spine after discectomy procedures, an in vivo study.

PubMed

Grunert, Peter; Moriguchi, Yu; Grossbard, Brian P; Ricart Arbona, Rodolfo J; Bonassar, Lawrence J; Härtl, Roger

2017-06-23

Discectomies are a common surgical treatment for disc herniations in the canine spine. However, the effect of these procedures on intervertebral disc tissue is not fully understood. The objective of this study was to assess degenerative changes of cervical spinal segments undergoing discectomy procedures, in vivo. Discectomies led to a 60% drop in disc height and 24% drop in foraminal height. Segments did not fuse but showed osteophyte formation as well as endplate sclerosis. MR imaging revealed terminal degenerative changes with collapse of the disc space and loss of T2 signal intensity. The endplates showed degenerative type II Modic changes. Quantitative MR imaging revealed that over 95% of Nucleus Pulposus tissue was extracted and that the nuclear as well as overall disc hydration significantly decreased. Histology confirmed terminal degenerative changes with loss of NP tissue, loss of Annulus Fibrosus organization and loss of cartilage endplate tissue. The bony endplate displayed sclerotic changes. Discectomies lead to terminal degenerative changes. Therefore, these procedures should be indicated with caution specifically when performed for prophylactic purposes.

Evaluation of colonoscopy technical skill levels by use of an objective kinematic-based system.

PubMed

Obstein, Keith L; Patil, Vaibhav D; Jayender, Jagadeesan; San José Estépar, Raúl; Spofford, Inbar S; Lengyel, Balazs I; Vosburgh, Kirby G; Thompson, Christopher C

2011-02-01

Colonoscopy requires training and experience to ensure accuracy and safety. Currently, no objective, validated process exists to determine when an endoscopist has attained technical competence. Kinematics data describing movements of laparoscopic instruments have been used in surgical skill assessment to define expert surgical technique. We have developed a novel system to record kinematics data during colonoscopy and quantitatively assess colonoscopist performance. To use kinematic analysis of colonoscopy to quantitatively assess endoscopic technical performance. Prospective cohort study. Tertiary-care academic medical center. This study involved physicians who perform colonoscopy. Application of a kinematics data collection system to colonoscopy evaluation. Kinematics data, validated task load assessment instrument, and technical difficulty visual analog scale. All 13 participants completed the colonoscopy to the terminal ileum on the standard colon model. Attending physicians reached the terminal ileum quicker than fellows (median time, 150.19 seconds vs 299.86 seconds; p<.01) with reduced path lengths for all 4 sensors, decreased flex (1.75 m vs 3.14 m; P=.03), smaller tip angulation, reduced absolute roll, and lower curvature of the endoscope. With performance of attending physicians serving as the expert reference standard, the mean kinematic score increased by 19.89 for each decrease in postgraduate year (P<.01). Overall, fellows experienced greater mental, physical, and temporal demand than did attending physicians. Small cohort size. Kinematic data and score calculation appear useful in the evaluation of colonoscopy technical skill levels. The kinematic score appears to consistently vary by year of training. Because this assessment is nonsubjective, it may be an improvement over current methods for determination of competence. Ongoing studies are establishing benchmarks and characteristic profiles of skill groups based on kinematics data. Copyright © 2011 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.

Genetic differences based on a beef terminal index are reflected in future phenotypic performance differences in commercial beef cattle.

PubMed

Connolly, S M; Cromie, A R; Berry, D P

2016-05-01

The increased demand for animal-derived protein and energy for human consumption will have to be achieved through a combination of improved animal genetic merit and better management strategies. The objective of the present study was to quantify whether differences in genetic merit among animals materialised into phenotypic differences in commercial herds. Carcass phenotypes on 156 864 animals from 7301 finishing herds were used, which included carcass weight (kg), carcass conformation score (scale 1 to 15), carcass fat score (scale 1 to 15) at slaughter as well as carcass price. The price per kilogram and the total carcass value that the producer received for the animal at slaughter was also used. A terminal index, calculated in the national genetic evaluations, was obtained for each animal. The index was based on pedigree index for calving performance, feed intake and carcass traits from the national genetic evaluations. Animals were categorised into four terminal index groups on the basis of genetic merit estimates that were derived before the expression of the phenotypic information by the validation animals. The association between terminal index and phenotypic performance at slaughter was undertaken using mixed models; whether the association differed by gender (i.e. young bulls, steers and heifers) or by early life experiences (animals born in a dairy herd or beef herd) was also investigated. The regression coefficient of phenotypic carcass weight, carcass conformation and carcass fat on their respective estimated breeding values (EBVs) was 0.92 kg, 1.08 units and 0.79 units, respectively, which is close to the expectation of one. Relative to animals in the lowest genetic merit group, animals in the highest genetic merit group had, on average, a 38.7 kg heavier carcass, with 2.21 units greater carcass conformation, and 0.82 units less fat. The superior genetic merit animals were, on average, slaughtered 6 days younger than their inferior genetic merit contemporaries. The superior carcass characteristics of the genetically elite animals materialised in carcasses worth €187 more than those of the lowest genetic merit animals. Although the phenotypic difference in carcass traits of animals divergent in terminal index differed statistically by animal gender and early life experience, the detected interactions were generally biologically small. This study clearly indicates that selection on an appropriate terminal index will produce higher performing animals and this was consistent across all production systems investigated.

Description and performance of a digital mobile satellite terminal

NASA Technical Reports Server (NTRS)

Lay, N.; Jedrey, T.; Parkyn, J.; Divsalar, D.

1990-01-01

A major goal of the Mobile Satellite Experiment (MSAT-X) program at the Jet Propulsion Lab (JPL) is the development of an advanced digital terminal for use in land mobile satellite communication. The terminal has been developed to minimize the risk of applying advanced technologies to future commercial mobile satellite systems (MSS). Testing with existing L band satellites was performed in fixed, land mobile and aeronautical mobile environments. JPL's development and tests of its mobile terminal have demonstrated the viability of narrowband digital voice communications in a land mobile environment through geostationary satellites. This paper provides a consolidated description of the terminal architecture and the performance of its individual elements.

48 CFR 49.201 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

....201 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS Additional Principles for Fixed-Price Contracts Terminated for Convenience 49.201... strict accounting principles, is the heart of a settlement. (b) The primary objective is to negotiate a...

Equipment Decisions: Micros, Terminals, or Typewriters.

ERIC Educational Resources Information Center

Swanson, Jean C.

1986-01-01

Discusses factors to be considered when deciding whether to buy typewriters, terminals, or microcomputers for the school typing room. Factors include (1) objectives of the typewriting program, (2) market needs, (3) student learning methods, (4) costs, and (5) instructional materials. (CH)

Image Processing for Planetary Limb/Terminator Extraction

NASA Technical Reports Server (NTRS)

Udomkesmalee, S.; Zhu, D. Q.; Chu, C. -C.

1995-01-01

A novel image segmentation technique for extracting limb and terminator of planetary bodies is proposed. Conventional edge- based histogramming approaches are used to trace object boundaries. The limb and terminator bifurcation is achieved by locating the harmonized segment in the two equations representing the 2-D parameterized boundary curve. Real planetary images from Voyager 1 and 2 served as representative test cases to verify the proposed methodology.

Development of a Low-Cost, Stand-Alone Microterminal for Support of Testing and Instruction. Final Report for Period January 1977-February 1978.

ERIC Educational Resources Information Center

Steffen, Dale A.; And Others

A study was undertaken to develop a microterminal for use in a computer-based instructional system. Objectives were to use new microprocessor technology to produce one terminal that is more effective and efficient than either the management terminal or the plasma type interactive terminal presently in use by the Air Force Advanced Instructional…

Iron Modifies Plasma FGF23 Differently in Autosomal Dominant Hypophosphatemic Rickets and Healthy Humans

PubMed Central

Peacock, Munro; Gray, Amie K.; Padgett, Leah R.; Hui, Siu L.; Econs, Michael J.

2011-01-01

Context: In autosomal dominant hypophosphatemic rickets (ADHR), fibroblast growth factor 23 (FGF23) resists cleavage, causing increased plasma FGF23 levels. The clinical phenotype includes variable onset during childhood or adulthood and waxing/waning of hypophosphatemia. Delayed onset after puberty in females suggests iron status may be important. Objective: Studies were performed to test the hypothesis that plasma C-terminal and intact FGF23 concentrations are related to serum iron concentrations in ADHR. Design and Setting: Cross-sectional and longitudinal studies of ADHR and a cross-sectional study in healthy subjects were conducted at an academic medical center. Participants: Participants included 37 subjects with ADHR mutations from four kindreds and 158 healthy adult controls. Main Outcome Measure: The relationships of serum iron concentrations with plasma C-terminal and intact FGF23 concentrations were evaluated. Results: Serum phosphate and 1,25-dihydroxyvitamin D correlated negatively with C-terminal FGF23 and intact FGF23 in ADHR but not in controls. Serum iron was negatively correlated to both C-terminal FGF23 (r = −0.386; P < 0.05) and intact FGF23 (r = −0.602; P < 0.0001) in ADHR. However, control subjects also demonstrated a negative relationship of serum iron with C-terminal FGF23 (r = −0.276; P < 0.001) but no relationship with intact FGF23. Longitudinally in ADHR subjects, C-terminal FGF23 and intact FGF23 concentrations changed negatively with iron concentrations (P < 0.001 and P = 0.055, respectively), serum phosphate changed negatively with C-terminal FGF23 and intact FGF23 (P < 0.001), and there was a positive relationship between serum iron and phosphate (P < 0.001). Conclusions: Low serum iron is associated with elevated FGF23 in ADHR. However, in controls, low serum iron was also associated with elevated C-terminal FGF23, but not intact FGF23, suggesting cleavage maintains homeostasis despite increased FGF23 expression. PMID:21880793

High-speed microprocessor characterization. Final report/project accomplishments summary, CRADA Number KCP-94-1004

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, L.W.

The objective of the project was to characterize and document the critical operating parameters of an 0.8-micron, 350-MHz, 32-bit microprocessor prototype. The roles of FM and T and the participant company were: FM and T -- evaluation performance of the prototype 32-bit microprocessor using the IDS5000 and Tektronix S3260 Integrated Circuit Test System; Corda -- design and build the prototype microprocessor. This project was terminated with nearly all of the planned activities unaddressed.

Personal Access Satellite System (PASS) study. Fiscal year 1989 results

NASA Technical Reports Server (NTRS)

Sue, Miles K. (Editor)

1990-01-01

The Jet Propulsion Laboratory is exploring the potential and feasibility of a personal access satellite system (PASS) that will offer the user greater freedom and mobility than existing or currently planned communications systems. Studies performed in prior years resulted in a strawman design and the identification of technologies that are critical to the successful implementation of PASS. The study efforts in FY-89 were directed towards alternative design options with the objective of either improving the system performance or alleviating the constraints on the user terminal. The various design options and system issues studied this year and the results of the study are presented.

Continued development of a non-proprietary, high-tension, cable end terminal system.

DOT National Transportation Integrated Search

2016-04-29

A non-proprietary, cable guardrail system is currently under development for the Midwest States Pooled Fund Program. : A cable guardrail end terminal was necessary to accompany the cable guardrail system. The objective of this research : project was ...

MSL EDL Entry Guidance using the Entry Terminal Point Controller

NASA Technical Reports Server (NTRS)

2006-01-01

The Mars Science Laboratory will be the first Mars mission to attempt a guided entry with the objective of safely delivering the entry vehicle to a survivable parachute deploy state within 10 km of the pre-designated landing site. The Entry Terminal Point Controller guidance algorithm is derived from the final phase Apollo Command Module guidance and, like Apollo, modulates the bank angle to control range based on deviations in range, altitude rate, and drag acceleration from a reference trajectory. For application to Mars landers which must make use of the tenuous Martian atmosphere, it is critical to balance the lift of the vehicle to minimize the range while still ensuring a safe deploy altitude. An overview of the process to generate optimized guidance settings is presented, discussing improvements made over the last four years. Performance tradeoffs between ellipse size and deploy altitude will be presented, along with imposed constraints of entry acceleration and heating. Performance sensitivities to the bank reversal deadbands, heading alignment, attitude initialization error, and atmospheric delivery errors are presented. Guidance settings for contingency operations, such as those appropriate for severe dust storm scenarios, are evaluated.

TRIO: Turbulent Response in Oxygen

NASA Technical Reports Server (NTRS)

Hecht, J. H.; Clemmons, J. H.; Katz, N.; Ben-Ami, M.; Carranza, P. A.; Larsen, M.

2005-01-01

This project was designed to build on the results from the successful launch of the Turbulent Oxygen Mixing Experiment (TOMEX) mother-daughter (instrumented and chemical-release) payload (21.126) that was launched in October 2000 from the White Sands Missile Range. The overall science objective was to investigate the evolution of the atmospheric response. at altitudes between 80 and 120 km, to the presence of unstable regions with vertical scales of the order of 1 to 10 km. TRIO was designed to use Na lidar measurements from the MAUUMALT observation on MAUI with a launch of a payload from Pacific Missile Range Facility (PMRF), located on Kauai. During this project, Aerospace participated in a Mission Initiation Conference. put together a science requirements document. performed a site visit to PMRF. prepared a CDR document. and developed a production and calibration procedure for one of the payload instruments. the 3-channel photometer. Unfortunately. NASA decided to terminate the program because of unforeseen (by NASA) range costs. This CDR document represents our view of this project at termination and provides a roadmap to perform this experiment should it be proposed again.

NASA TEERM Hexavalent Chrome Alternatives Projects

NASA Technical Reports Server (NTRS)

Kessel, Kurt R.; Rothgeb, Matthew

2011-01-01

The overall objective of the Hex Chrome Free Coatings for Electronics project is to evaluate and test pretreatment coating systems not containing hexavalent chrome in avionics and electronics housing applications. This objective will be accomplished by testing strong performing coating systems from prior NASA and DoD testing or new coating systems as determined by the stakeholders. The technical stakeholders have agreed that this protocol will focus specifically on Class 3 coatings. Original Equipment Manufacturers (OEMs), depots, and support contractors have to be prepared to deal with an electronics supply chain that increasingly provides parts with lead-free finishes, some labeled no differently and intermingled with their SnPb counterparts. Allowance of lead-free components presents one of the greatest risks to the reliability of military and aerospace electronics. The introduction of components with lead-free terminations, termination finishes, or circuit boards presents a host of concerns to customers, suppliers, and maintainers of aerospace and military electronic systems such as: 1. Electrical shorting due to tin whiskers 2. Incompatibility of lead-free processes and parameters (including higher melting points of lead-free alloys) with other materials in the system 3. Unknown material properties and incompatibilities that could reduce solder joint reliability

Laser data transfer flight experiment definition

NASA Technical Reports Server (NTRS)

Merritt, J. R.

1975-01-01

A set of laser communication flight experiments to be performed between a relay satellite, ground terminals, and space shuttles were synthesized and evaluated. Results include a definition of the space terminals, NASA ground terminals, test methods, and test schedules required to perform the experiments.

A New Computational Technique for the Generation of Optimised Aircraft Trajectories

NASA Astrophysics Data System (ADS)

Chircop, Kenneth; Gardi, Alessandro; Zammit-Mangion, David; Sabatini, Roberto

2017-12-01

A new computational technique based on Pseudospectral Discretisation (PSD) and adaptive bisection ɛ-constraint methods is proposed to solve multi-objective aircraft trajectory optimisation problems formulated as nonlinear optimal control problems. This technique is applicable to a variety of next-generation avionics and Air Traffic Management (ATM) Decision Support Systems (DSS) for strategic and tactical replanning operations. These include the future Flight Management Systems (FMS) and the 4-Dimensional Trajectory (4DT) planning and intent negotiation/validation tools envisaged by SESAR and NextGen for a global implementation. In particular, after describing the PSD method, the adaptive bisection ɛ-constraint method is presented to allow an efficient solution of problems in which two or multiple performance indices are to be minimized simultaneously. Initial simulation case studies were performed adopting suitable aircraft dynamics models and addressing a classical vertical trajectory optimisation problem with two objectives simultaneously. Subsequently, a more advanced 4DT simulation case study is presented with a focus on representative ATM optimisation objectives in the Terminal Manoeuvring Area (TMA). The simulation results are analysed in-depth and corroborated by flight performance analysis, supporting the validity of the proposed computational techniques.

Conflict termination and military strategy: Coercion, persuasion, and war

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cimbala, S.J.; Dunn, K.A.

1987-01-01

The contributors examine a wide variety of topics ranging from superpower views on conflict termination to past, present, and future U.S. military service contributions. They aim to highlight the importance of thinking about conflict termination goals and objectives in peacetime to insure that plans that may be used in war have been carefully evaluated outside the heat of battle, when the emotions created by war might cloud decision making.

Domestic Violence, Unwanted Pregnancy and Pregnancy Termination among Urban Women of Bangladesh

PubMed Central

2013-01-01

Objective This paper explores the relationship between domestic violence against women inflicted by husbands, unwanted pregnancy and pregnancy termination of Bangladeshi urban women. Materials and methods The study used the nationally representative 2007 Bangladesh Demographic and Health Survey (BDHS) data. The BDHS covered a representative sample of 10,996 ever married women from rural and urban areas. The BDHS used a separate module to collect information from women regarding domestic violence. The survey gathered information of domestic violence from 1,013 urban women which are the basis of the study. Simple cross tabulation, bivariate and multivariate statistical analyses were performed to analyzing data. Results Overall, the lifetime prevalence of domestic violence was 47.5%. Of the most recent pregnancies, 15.6% were unwanted and 16.0% of the women terminated pregnancy in their marital life. The multivariate binary logistic regression analyses yielded quantitatively important and reliable estimate of unwanted pregnancy and pregnancy termination. The regression analyses yielded significantly (p < 0.05) increased risk of unwanted pregnancy only for physical violence (OR = 2.35, 95% CI = 1.28-4.32) and for both physical and sexual violence (OR = 2.27, 95% CI = 1.02-5.28), and higher risk of pregnancy termination for only physical violence (OR = 1.41, 95% CI = 0.95-2.10) and for both physical and sexual violence (OR = 1.81, 95% CI = 1.07-3.04) than women who were never abused. Current age, higher parity and early marriage are also important determinants of unwanted pregnancy and pregnancy termination. Conclusion Violence against women inflicted by husbands is commonplace in Bangladesh. Any strategy to reduce the burden of unwanted pregnancy and induced abortion should include prevention of violence against women and strengthening women's sexual and reproductive health. PMID:24971097

Synchronous parallel system for emulation and discrete event simulation

NASA Technical Reports Server (NTRS)

Steinman, Jeffrey S. (Inventor)

1992-01-01

A synchronous parallel system for emulation and discrete event simulation having parallel nodes responds to received messages at each node by generating event objects having individual time stamps, stores only the changes to state variables of the simulation object attributable to the event object, and produces corresponding messages. The system refrains from transmitting the messages and changing the state variables while it determines whether the changes are superseded, and then stores the unchanged state variables in the event object for later restoral to the simulation object if called for. This determination preferably includes sensing the time stamp of each new event object and determining which new event object has the earliest time stamp as the local event horizon, determining the earliest local event horizon of the nodes as the global event horizon, and ignoring the events whose time stamps are less than the global event horizon. Host processing between the system and external terminals enables such a terminal to query, monitor, command or participate with a simulation object during the simulation process.

Synchronous Parallel System for Emulation and Discrete Event Simulation

NASA Technical Reports Server (NTRS)

Steinman, Jeffrey S. (Inventor)

2001-01-01

A synchronous parallel system for emulation and discrete event simulation having parallel nodes responds to received messages at each node by generating event objects having individual time stamps, stores only the changes to the state variables of the simulation object attributable to the event object and produces corresponding messages. The system refrains from transmitting the messages and changing the state variables while it determines whether the changes are superseded, and then stores the unchanged state variables in the event object for later restoral to the simulation object if called for. This determination preferably includes sensing the time stamp of each new event object and determining which new event object has the earliest time stamp as the local event horizon, determining the earliest local event horizon of the nodes as the global event horizon, and ignoring events whose time stamps are less than the global event horizon. Host processing between the system and external terminals enables such a terminal to query, monitor, command or participate with a simulation object during the simulation process.

L-band mobile terminal antennas for helicopters

NASA Technical Reports Server (NTRS)

Wu, T. K.; Farazian, K.; Golshan, N.; Divsalar, D.; Hinedi, S.

1993-01-01

The feasibility of using a low gain antenna (LGA) as a mobile terminal antenna for a helicopter is described in this paper. The objectives are to select the lowest cost antenna system which can be easily mounted on a helicopter and capable of communicating with a satellite, and to determine the best antenna position on the helicopter to mitigate the signal blockage due to rotor blades and the multipath effect from the helicopter's body. The omnidirectional LGA is selected because it is simple, reliable, and low cost. The helix antenna is selected among the many LGA's because it is the most economical one and has the widest elevation beamwidth. Both 2-arm and 4-arm helices are studied experimentally to determine the antenna's performance and the scattering effects from the helicopter's body. It is found that the LGA should be located near the tail section and at least eight inches above the helicopter.

Biaxial Creep Specimen Fabrication

DOE Office of Scientific and Technical Information (OSTI.GOV)

JL Bump; RF Luther

This report documents the results of the weld development and abbreviated weld qualification efforts performed by Pacific Northwest National Laboratory (PNNL) for refractory metal and superalloy biaxial creep specimens. Biaxial creep specimens were to be assembled, electron beam welded, laser-seal welded, and pressurized at PNNL for both in-pile (JOYO reactor, O-arai, Japan) and out-of-pile creep testing. The objective of this test campaign was to evaluate the creep behavior of primary cladding and structural alloys under consideration for the Prometheus space reactor. PNNL successfully developed electron beam weld parameters for six of these materials prior to the termination of the Navalmore » Reactors program effort to deliver a space reactor for Project Prometheus. These materials were FS-85, ASTAR-811C, T-111, Alloy 617, Haynes 230, and Nirnonic PE16. Early termination of the NR space program precluded the development of laser welding parameters for post-pressurization seal weldments.« less

Knowledge-Based Scheduling of Arrival Aircraft in the Terminal Area

NASA Technical Reports Server (NTRS)

Krzeczowski, K. J.; Davis, T.; Erzberger, H.; Lev-Ram, Israel; Bergh, Christopher P.

1995-01-01

A knowledge based method for scheduling arrival aircraft in the terminal area has been implemented and tested in real time simulation. The scheduling system automatically sequences, assigns landing times, and assign runways to arrival aircraft by utilizing continuous updates of aircraft radar data and controller inputs. The scheduling algorithm is driven by a knowledge base which was obtained in over two thousand hours of controller-in-the-loop real time simulation. The knowledge base contains a series of hierarchical 'rules' and decision logic that examines both performance criteria, such as delay reductions, as well as workload reduction criteria, such as conflict avoidance. The objective of the algorithm is to devise an efficient plan to land the aircraft in a manner acceptable to the air traffic controllers. This paper describes the scheduling algorithms, gives examples of their use, and presents data regarding their potential benefits to the air traffic system.

Low cost Ku-band earth terminals for voice/data/facsimile

NASA Technical Reports Server (NTRS)

Kelley, R. L.

1977-01-01

A Ku-band satellite earth terminal capable of providing two way voice/facsimile teleconferencing, 128 Kbps data, telephone, and high-speed imagery services is proposed. Optimized terminal cost and configuration are presented as a function of FDMA and TDMA approaches to multiple access. The entire terminal from the antenna to microphones, speakers and facsimile equipment is considered. Component cost versus performance has been projected as a function of size of the procurement and predicted hardware innovations and production techniques through 1985. The lowest cost combinations of components has been determined in a computer optimization algorithm. The system requirements including terminal EIRP and G/T, satellite size, power per spacecraft transponder, satellite antenna characteristics, and link propagation outage were selected using a computerized system cost/performance optimization algorithm. System cost and terminal cost and performance requirements are presented as a function of the size of a nationwide U.S. network. Service costs are compared with typical conference travel costs to show the viability of the proposed terminal.

Data-linked pilot reply time on controller workload and communication in a simulated terminal option

DOT National Transportation Integrated Search

2001-05-01

This report describes an analysis of air traffic control communication and workload in a simulated terminal radar approach : control environment. The objective of this study was to investigate how pilot-to-controller data-link acknowledgment time : m...

Rural inland waterways economic impact kit : users guide

DOT National Transportation Integrated Search

2000-08-01

The primary objective of the project was to develop a PC-based kit allowing users to evaluate the economic impact of existing rural inland waterways ports and terminals. By using the Kit, the importance to a community of a port and terminals can be q...

Rural inland waterways economic impact kit : analysis manual

DOT National Transportation Integrated Search

2000-08-01

The primary objective of the project was to develop a PC-based kit allowing users to evaluate the economic impact of existing rural inland waterways ports and terminals. By using the Kit, the importance to a community of a port and terminals can be q...

Due process model of procedural justice in performance appraisal: promotion versus termination scenarios.

PubMed

Kataoka, Heloneida C; Cole, Nina D; Flint, Douglas A

2006-12-01

In a laboratory study, 318 student participants (148 male, 169 female, and one who did not report sex; M age 25.0, SD = 6.0) in introductory organizational behavior classes responded to scenarios in which performance appraisal resulted in either employee promotion or termination. Each scenario had varying levels of three procedural justice criteria for performance appraisal. For both promotion and termination outcomes, analysis showed that, as the number of criteria increased, perceptions of procedural fairness increased. A comparison between the two outcomes showed that perceptions of fairness were significantly stronger for the promotion outcome than for termination.

War Termination Criteria: Linking Strategic Policy and Operational Objectives

DTIC Science & Technology

2014-04-16

leaders of the period, as published in biographies and historical texts, provide insights to the effectiveness of the campaigns. This section outlined the...Critical Survey. Jerusalem : Hebrew University, 1978. Handel, Michael I. “The Study of War Termination.” Journal of Strategic Studies 1, 1978

The development of catalytic nucleophilic additions of terminal alkynes in water.

PubMed

Li, Chao-Jun

2010-04-20

One of the major research endeavors in synthetic chemistry over the past two decades is the exploration of synthetic methods that work under ambient atmosphere with benign solvents, that maximize atom utilization, and that directly transform natural resources, such as renewable biomass, from their native states into useful chemical products, thus avoiding the need for protecting groups. The nucleophilic addition of terminal alkynes to various unsaturated electrophiles is a classical (textbook) reaction in organic chemistry, allowing the formation of a C-C bond while simultaneously introducing the alkyne functionality. A prerequisite of this classical reaction is the stoichiometric generation of highly reactive metal acetylides. Over the past decade, our laboratory and others have been exploring an alternative, the catalytic and direct nucleophilic addition of terminal alkynes to unsaturated electrophiles in water. We found that various terminal alkynes can react efficiently with a wide range of such electrophiles in water (or organic solvent) in the presence of simple and readily available catalysts, such as copper, silver, gold, iron, palladium, and others. In this Account, we describe the development of these synthetic methods, focusing primarily on results from our laboratory. Our studies include the following: (i) catalytic reaction of terminal alkynes with acid chloride, (ii) catalytic addition of terminal alkynes to aldehydes and ketones, (iii) catalytic addition of alkynes to C=N bonds, and (iv) catalytic conjugate additions. Most importantly, these reactions can tolerate various functional groups and, in many cases, perform better in water than in organic solvents, clearly defying classical reactivities predicated on the relative acidities of water, alcohols, and terminal alkynes. We further discuss multicomponent and enantioselective reactions that were developed. These methods provide an alternative to the traditional requirement of separate steps in classical alkyne reactions, including the pregeneration of metal acetylides with stoichiometric, highly basic reagents and the preprotection of sensitive functional groups. Accordingly, these techniques have greatly enhanced overall synthetic efficiencies and furthered our long-term objective of developing Grignard-type reactions in water.

Operation and evaluation of the Terminal Configured Vehicle Mission Simulator in an automated terminal area metering and spacing ATC environment

NASA Technical Reports Server (NTRS)

Houck, J. A.

1980-01-01

This paper describes the work being done at the National Aeronautics and Space Administration's Langley Research Center on the development of a mission simulator for use in the Terminal Configured Vehicle Program. A brief description of the goals and objectives of the Terminal Configured Vehicle Program is presented. A more detailed description of the Mission Simulator, in its present configuration, and its components is provided. Finally, a description of the first research study conducted in the Mission Simulator is presented along with a discussion of some preliminary results from this study.

Mathematics Education: Student Terminal Goals, Program Goals, and Behavioral Objectives.

ERIC Educational Resources Information Center

Mesa Public Schools, AZ.

Behavioral objectives are listed for the primary, intermediate and junior high mathematics curriculum in the Mesa Public Schools (Arizona). Lists of specific objectives are given by level for sets, symbol recognition, number operations, mathematical structures, measurement and problem solving skills. (JP)

Rooting traits of peanut genotypes with different yield responses to terminal drought

USDA-ARS?s Scientific Manuscript database

Drought at pod filling can severely reduce yield of peanut. Better root systems can reduce yield loss from drought. However, the relationship of root characters with yield under terminal drought is not well understood. The objective of this study was to investigate the responses of peanut genotyp...

Plant, soil and weather-based cues for irrigation termination timing in soybean.

USDA-ARS?s Scientific Manuscript database

Irrigation termination timing was evaluated on Mississippi County commercial farms in 2014 and 2015 in furrow-irrigated fields with Sharkey clay soils. A major objective was to validate and expand irrigation timing recommendations that pair plant growth measures with weather cues including use of lo...

Operation and evaluation of the terminal configured vehicle mission simulator in an automated terminal area metering and spacing ATC environment

NASA Technical Reports Server (NTRS)

Houck, J. A.

1979-01-01

The development of a mission simulator for use in the Terminal Configured Vehicle (TCV) program is outlined. The broad objectives of the TCV program are to evaluate new concepts in airborne systems and in operational flight procedures. These evaluations are directed toward improving terminal area capacity and efficiency, improving approach and landing capability in adverse weather, and reducing noise impact in the terminal area. A description is given of the design features and operating principles of the two major components of the TCV Mission Simulator: the TCV Aft Flight Deck Simulation and the Terminal Area Air Traffic Model Simulation, and their merger to form the TCV Mission Simulator. The first research study conducted in the Mission Simulator is presented along with some preliminary results.

Delivery performance of conventional aircraft by terminal-area, time-based air traffic control: A real-time simulation evaluation

NASA Technical Reports Server (NTRS)

Credeur, Leonard; Houck, Jacob A.; Capron, William R.; Lohr, Gary W.

1990-01-01

A description and results are presented of a study to measure the performance and reaction of airline flight crews, in a full workload DC-9 cockpit, flying in a real-time simulation of an air traffic control (ATC) concept called Traffic Intelligence for the Management of Efficient Runway-scheduling (TIMER). Experimental objectives were to verify earlier fast-time TIMER time-delivery precision results and obtain data for the validation or refinement of existing computer models of pilot/airborne performance. Experimental data indicated a runway threshold, interarrival-time-error standard deviation in the range of 10.4 to 14.1 seconds. Other real-time system performance parameters measured include approach speeds, response time to controller turn instructions, bank angles employed, and ATC controller message delivery-time errors.

Carpentry. Competency Statements/Objectives and Reference Guide. Revised.

ERIC Educational Resources Information Center

North Carolina State Dept. of Public Instruction, Raleigh. Div. of Vocational Education.

This curriculum guide provides competency statements/objectives for an 11th- to 12th-grade trade and industrial education course in carpentry. The first half of the guide consists of competency statements for the 35 units of the curriculum. Each competency statement consists of a terminal objective and specific objectives for each unit, referenced…

Mechanical Systems. Competency Statements/Objectives and Reference Guide.

ERIC Educational Resources Information Center

North Carolina State Dept. of Public Instruction, Raleigh. Div. of Vocational Education.

This curriculum guide provides competency statements/objectives for an 11th- to 12th-grade trade and industrial education course in mechanical systems. The first half of the guide consists of competency statements for the 53 units of the curriculum. Each competency statement consists of a terminal objective and specific objectives for each unit,…

To die, to sleep: US physicians' religious and other objections to physician-assisted suicide, terminal sedation, and withdrawal of life support.

PubMed

Curlin, Farr A; Nwodim, Chinyere; Vance, Jennifer L; Chin, Marshall H; Lantos, John D

2008-01-01

This study analyzes data from a national survey to estimate the proportion of physicians who currently object to physician-assisted suicide (PAS), terminal sedation (TS), and withdrawal of artificial life support (WLS), and to examine associations between such objections and physician ethnicity, religious characteristics, and experience caring for dying patients. Overall, 69% of the US physicians object to PAS, 18% to TS, and 5% to WLS. Highly religious physicians are more likely than those with low religiosity to object to both PAS (84% vs 55%, P < .001) and TS (25% vs 12%, P < .001). Objection to PAS or TS is also associated with being of Asian ethnicity, of Hindu religious affiliation, and having more experience caring for dying patients. These findings suggest that, with respect to morally contested interventions at the end of life, the medical care patients receive will vary based on their physicians' religious characteristics, ethnicity, and experience caring for dying patients.

Terminating the Audit of the National Flood Insurance Program’s Fiscal 1980 Financial Statements.

DTIC Science & Technology

1981-09-21

7 AD-A107 188 GENERAL ACCOUNTING OFFICE WASHINGTON DC ACCOUNTING A ETC F/G 5/1 TERMINATING THE AUDIT OF THE NATIONAL FLOOD INSURANCE PROGRAN S-,-ETC...Management Agency Dear Mr. Giuffrida: A Subject: Terminating the Audit of the National Floodr .) Insurance Program’s Fiscal 1980 Financial...objective of the audit was to express an opinion on the NFIP’s < fiscal 1980 financial statements. We will not meet this objec- tive, however, because

Operational benefits from the terminal configured vehicle

NASA Technical Reports Server (NTRS)

Reeder, J. P.; Schmitz, R. A.; Clark, L. V.

1979-01-01

The NASA Terminal Configured Vehicle is a flying laboratory used to conduct research and development on improved airborne systems (including avionics) and operational flight procedures, with particular emphasis on utilization in the terminal area environment. The objectives of this technology development activity, focused on conventional transport aircraft, are to develop and demonstrate improvements which can lead to increased airport and runway capacity, increased air traffic controller productivity, energy efficient terminal area operations, reduced weather minima with safety, and reduced community noise by use of appropriate procedures. This paper discusses some early results of this activity in addition to defining present efforts and future research plans.

Correlations between measures of feed efficiency and feedlot return for F1 lambs

USDA-ARS?s Scientific Manuscript database

Objective estimates of feedlot return for progeny of terminal-sire breeds of sheep are needed to improve lamb profitability. Thus, we used recent economic data to determine the effects of terminal-sire breed on returns of F1 lambs. Annually for 3 yr, Columbia, USMARC Composite, Suffolk, and Texel ra...

Using Initial, Derived, and Terminal Credibility to Help Students Understand How They Are Perceived by Others

ERIC Educational Resources Information Center

Berry, Marcia

2018-01-01

Courses: Public Speaking, Interpersonal Communication, Organizational Communication, Introduction to Communication Studies, Business Communication. Objectives: The goal for this activity is not only to provide students with an understanding of their initial, derived, and terminal credibility when relating a personal, edifying story but also to…

Inheritance on processes, exemplified on distributed termination detection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thomsen, K.S.

1987-02-01

A multiple inheritance mechanism on processes is designed and presented within the framework of a small object oriented language. Processes are described in classes, and the different action parts of a process inherited from different classes are executed in a coroutine-like style called alternation. The inheritance mechanism is a useful tool for factorizing the description of common aspects of processes. This is demonstrated within the domain of distributed programming by using the inheritance mechanism to factorize the description of distributed termination detection algorithms from the description of the distributed main computations for which termination is to be detected. A clearmore » separation of concerns is obtained, and arbitrary combinations of terminations detection algorithms and main computations can be formed. The same termination detection classes can also be used for more general purposes within distributed programming, such as detecting termination of each phase in a multi-phase main computation.« less

48 CFR 52.249-6 - Termination (Cost-Reimbursement).

Code of Federal Regulations, 2010 CFR

2010-10-01

...-Reimbursement). 52.249-6 Section 52.249-6 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION....249-6 Termination (Cost-Reimbursement). As prescribed in 49.503(a)(1), insert the following clause: Termination (Cost-Reimbursement) (MAY 2004) (a) The Government may terminate performance of work under this...

Schizophrenia and induced abortions: A national register-based follow-up study among Finnish women born between 1965-1980 with schizophrenia or schizoaffective disorder.

PubMed

Simoila, Laura; Isometsä, Erkki; Gissler, Mika; Suvisaari, Jaana; Sailas, Eila; Halmesmäki, Erja; Lindberg, Nina

2018-02-01

The objectives of this study were to investigate, in women with schizophrenia or schizoaffective disorder, the number and incidence of induced abortions (= pregnancy terminations performed by a physician), their demographic characteristics, use of contraceptives, plus indications of and complications related to pregnancy termination. Using the Care Register for Health Care, we identified Finnish women born between the years 1965-1980 who were diagnosed with either schizophrenia or schizoaffective disorder during the follow-up period ending 31.12.2013. For each case, five age- and place-of-birth- matched controls were obtained from the Population Register of Finland. Information about births and induced abortions were obtained from the Medical Birth Register and the Induced Abortion Register. The number and incidence of induced abortions per 1000 follow-up years did not differ between cases and their controls. However, due to fewer pregnancies, cases exhibited an over 2-fold increased risk of pregnancy termination (RR 2.28; 95% CI 2.20-2.36). Cases were younger, were more often without a partner at the time of induced abortion, and their pregnancies resulted more often from a lack of contraception. Among cases, the indication for pregnancy termination was more often mother-to-be's medical condition. Induced abortions after 12weeks gestation were more common among cases. However, cases had no more complications related to termination. The incidence of induced abortions among Finnish women with schizophrenia or schizoaffective disorder is similar to the general population, but their risk per pregnancy over two-fold. They need effective, affordable family planning services and long-term premeditated contraception. Copyright © 2017 Elsevier B.V. All rights reserved.

20 CFR 633.315 - Replacement, corrective action, termination.

Code of Federal Regulations, 2010 CFR

2010-04-01

...; documented information from the Inspector General or gained through incident reports of poor performance... whose performance has been found deficient, but not sufficient to warrant termination for cause or... successive periods within 30 days after they are due; (ii) Failure to submit required quarterly performance...

The PLATO IV Communications System.

ERIC Educational Resources Information Center

Sherwood, Bruce Arne; Stifle, Jack

The PLATO IV computer-based educational system contains its own communications hardware and software for operating plasma-panel graphics terminals. Key echoing is performed by the central processing unit: every key pressed at a terminal passes through the entire system before anything appears on the terminal's screen. Each terminal is guaranteed…

A Simulation Based Approach to Optimize Berth Throughput Under Uncertainty at Marine Container Terminals

NASA Technical Reports Server (NTRS)

Golias, Mihalis M.

2011-01-01

Berth scheduling is a critical function at marine container terminals and determining the best berth schedule depends on several factors including the type and function of the port, size of the port, location, nearby competition, and type of contractual agreement between the terminal and the carriers. In this paper we formulate the berth scheduling problem as a bi-objective mixed-integer problem with the objective to maximize customer satisfaction and reliability of the berth schedule under the assumption that vessel handling times are stochastic parameters following a discrete and known probability distribution. A combination of an exact algorithm, a Genetic Algorithms based heuristic and a simulation post-Pareto analysis is proposed as the solution approach to the resulting problem. Based on a number of experiments it is concluded that the proposed berth scheduling policy outperforms the berth scheduling policy where reliability is not considered.

The Inclusion of Disability as a Condition for Termination of Parental Rights

ERIC Educational Resources Information Center

Lightfoot, Elizabeth; Hill, Katharine; LaLiberte, Traci

2010-01-01

Objectives: All 50 states and the District of Columbia have statutes outlining the grounds for terminating parental rights (TPR) in relation to child abuse and neglect. Although recent research has found that parents with disabilities are not more likely to maltreat their children than parents without disabilities ([Glaun and Brown, 1999] and…

Effects of a one year physical activity program on serum C Terminal Agrin Fragment (CAF) concentrations among mobility limited older adults

USDA-ARS?s Scientific Manuscript database

OBJECTIVES: C terminal Agrin Fragment (CAF) has been proposed as a potential circulating biomarker for predicting changes in physical function among older adults. To determine the effect of a one year PA intervention on changes in CAF concentrations and to evaluate baseline and longitudinal associat...

Engineering flight and guest pilot evaluation report, phase 2. [DC 8 aircraft

NASA Technical Reports Server (NTRS)

Morrison, J. A.; Anderson, E. B.; Brown, G. W.; Schwind, G. K.

1974-01-01

Prior to the flight evaluation, the two-segment profile capabilities of the DC-8-61 were evaluated and flight procedures were developed in a flight simulator at the UA Flight Training Center in Denver, Colorado. The flight evaluation reported was conducted to determine the validity of the simulation results, further develop the procedures and use of the area navigation system in the terminal area, certify the system for line operation, and obtain evaluations of the system and procedures by a number of pilots from the industry. The full area navigation capabilities of the special equipment installed were developed to provide terminal area guidance for two-segment approaches. The objectives of this evaluation were: (1) perform an engineering flight evaluation sufficient to certify the two-segment system for the six-month in-service evaluation; (2) evaluate the suitability of a modified RNAV system for flying two-segment approaches; and (3) provide evaluation of the two-segment approach by management and line pilots.

An aeronautical mobile satellite experiment

NASA Technical Reports Server (NTRS)

Jedrey, T. C.; Dessouky, K. I.; Lay, N. E.

1990-01-01

The various activities and findings of a NASA/FAA/COMSAT/INMARSAT collaborative aeronautical mobile satellite experiment are detailed. The primary objective of the experiment was to demonstrate and evaluate an advanced digital mobile satellite terminal developed at the Jet Propulsion Laboratory under the NASA Mobile Satellite Program. The experiment was a significant milestone for NASA/JPL, since it was the first test of the mobile terminal in a true mobile satellite environment. The results were also of interest to the general mobile satellite community because of the advanced nature of the technologies employed in the terminal.

Evaluations of Guardrail Breakaway Cable Terminals

DOT National Transportation Integrated Search

1982-05-01

Currently recommended guardrail and median barrier breakaway cable terminals (BCT) were to be evaluated for performance with 1800-lb (800-kg) class minicars. Early findings indicated unsatisfactory performance of the guardrail BCT for end-on impacts ...

42 CFR 421.205 - Termination by the Secretary.

Code of Federal Regulations, 2010 CFR

2010-10-01

... for termination. The Secretary may terminate a contract with a carrier at any time if he or she... performed its function in a manner inconsistent with the effective and efficient administration of the... intent to terminate the contract, the carrier may request a hearing within 20 days after the date on the...

9 CFR 590.161 - Termination of plant approval.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Termination of plant approval. 590.161... Service § 590.161 Termination of plant approval. When inspection service is not performed at any plant for a period of at least 90 days, plant approval shall terminate upon notice by the Administrator...

9 CFR 590.161 - Termination of plant approval.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Termination of plant approval. 590.161... Service § 590.161 Termination of plant approval. When inspection service is not performed at any plant for a period of at least 90 days, plant approval shall terminate upon notice by the Administrator...

9 CFR 590.161 - Termination of plant approval.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Termination of plant approval. 590.161... Service § 590.161 Termination of plant approval. When inspection service is not performed at any plant for a period of at least 90 days, plant approval shall terminate upon notice by the Administrator...

9 CFR 590.161 - Termination of plant approval.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Termination of plant approval. 590.161... Service § 590.161 Termination of plant approval. When inspection service is not performed at any plant for a period of at least 90 days, plant approval shall terminate upon notice by the Administrator...

Rover nuclear rocket engine program: Overview of rover engine tests

NASA Technical Reports Server (NTRS)

Finseth, J. L.

1991-01-01

The results of nuclear rocket development activities from the inception of the ROVER program in 1955 through the termination of activities on January 5, 1973 are summarized. This report discusses the nuclear reactor test configurations (non cold flow) along with the nuclear furnace demonstrated during this time frame. Included in the report are brief descriptions of the propulsion systems, test objectives, accomplishments, technical issues, and relevant test results for the various reactor tests. Additionally, this document is specifically aimed at reporting performance data and their relationship to fuel element development with little or no emphasis on other (important) items.

20 CFR 632.23 - Termination and corrective action of a CAP and/or Master Plan.

Code of Federal Regulations, 2010 CFR

2010-04-01

... substantiates serious management, fiscal and/or performance problems, information from the Inspector General or gained through incident reports of poor performance, serious administrative problems and/or inability to... termination: (1) Poor performance and inability to meet Federal standards related to such debt collection...

Real-time vision, tactile cues, and visual form agnosia: removing haptic feedback from a “natural” grasping task induces pantomime-like grasps

PubMed Central

Whitwell, Robert L.; Ganel, Tzvi; Byrne, Caitlin M.; Goodale, Melvyn A.

2015-01-01

Investigators study the kinematics of grasping movements (prehension) under a variety of conditions to probe visuomotor function in normal and brain-damaged individuals. “Natural” prehensile acts are directed at the goal object and are executed using real-time vision. Typically, they also entail the use of tactile, proprioceptive, and kinesthetic sources of haptic feedback about the object (“haptics-based object information”) once contact with the object has been made. Natural and simulated (pantomimed) forms of prehension are thought to recruit different cortical structures: patient DF, who has visual form agnosia following bilateral damage to her temporal-occipital cortex, loses her ability to scale her grasp aperture to the size of targets (“grip scaling”) when her prehensile movements are based on a memory of a target previewed 2 s before the cue to respond or when her grasps are directed towards a visible virtual target but she is denied haptics-based information about the target. In the first of two experiments, we show that when DF performs real-time pantomimed grasps towards a 7.5 cm displaced imagined copy of a visible object such that her fingers make contact with the surface of the table, her grip scaling is in fact quite normal. This finding suggests that real-time vision and terminal tactile feedback are sufficient to preserve DF’s grip scaling slopes. In the second experiment, we examined an “unnatural” grasping task variant in which a tangible target (along with any proxy such as the surface of the table) is denied (i.e., no terminal tactile feedback). To do this, we used a mirror-apparatus to present virtual targets with and without a spatially coincident copy for the participants to grasp. We compared the grasp kinematics from trials with and without terminal tactile feedback to a real-time-pantomimed grasping task (one without tactile feedback) in which participants visualized a copy of the visible target as instructed in our laboratory in the past. Compared to natural grasps, removing tactile feedback increased RT, slowed the velocity of the reach, reduced in-flight grip aperture, increased the slopes relating grip aperture to target width, and reduced the final grip aperture (FGA). All of these effects were also observed in the real time-pantomime grasping task. These effects seem to be independent of those that arise from using the mirror in general as we also compared grasps directed towards virtual targets to those directed at real ones viewed directly through a pane of glass. These comparisons showed that the grasps directed at virtual targets increased grip aperture, slowed the velocity of the reach, and reduced the slopes relating grip aperture to the widths of the target. Thus, using the mirror has real consequences on grasp kinematics, reflecting the importance of task-relevant sources of online visual information for the programming and updating of natural prehensile movements. Taken together, these results provide compelling support for the view that removing terminal tactile feedback, even when the grasps are target-directed, induces a switch from real-time visual control towards one that depends more on visual perception and cognitive supervision. Providing terminal tactile feedback and real-time visual information can evidently keep the dorsal visuomotor system operating normally for prehensile acts. PMID:25999834

Real-time vision, tactile cues, and visual form agnosia: removing haptic feedback from a "natural" grasping task induces pantomime-like grasps.

PubMed

Whitwell, Robert L; Ganel, Tzvi; Byrne, Caitlin M; Goodale, Melvyn A

2015-01-01

Investigators study the kinematics of grasping movements (prehension) under a variety of conditions to probe visuomotor function in normal and brain-damaged individuals. "Natural" prehensile acts are directed at the goal object and are executed using real-time vision. Typically, they also entail the use of tactile, proprioceptive, and kinesthetic sources of haptic feedback about the object ("haptics-based object information") once contact with the object has been made. Natural and simulated (pantomimed) forms of prehension are thought to recruit different cortical structures: patient DF, who has visual form agnosia following bilateral damage to her temporal-occipital cortex, loses her ability to scale her grasp aperture to the size of targets ("grip scaling") when her prehensile movements are based on a memory of a target previewed 2 s before the cue to respond or when her grasps are directed towards a visible virtual target but she is denied haptics-based information about the target. In the first of two experiments, we show that when DF performs real-time pantomimed grasps towards a 7.5 cm displaced imagined copy of a visible object such that her fingers make contact with the surface of the table, her grip scaling is in fact quite normal. This finding suggests that real-time vision and terminal tactile feedback are sufficient to preserve DF's grip scaling slopes. In the second experiment, we examined an "unnatural" grasping task variant in which a tangible target (along with any proxy such as the surface of the table) is denied (i.e., no terminal tactile feedback). To do this, we used a mirror-apparatus to present virtual targets with and without a spatially coincident copy for the participants to grasp. We compared the grasp kinematics from trials with and without terminal tactile feedback to a real-time-pantomimed grasping task (one without tactile feedback) in which participants visualized a copy of the visible target as instructed in our laboratory in the past. Compared to natural grasps, removing tactile feedback increased RT, slowed the velocity of the reach, reduced in-flight grip aperture, increased the slopes relating grip aperture to target width, and reduced the final grip aperture (FGA). All of these effects were also observed in the real time-pantomime grasping task. These effects seem to be independent of those that arise from using the mirror in general as we also compared grasps directed towards virtual targets to those directed at real ones viewed directly through a pane of glass. These comparisons showed that the grasps directed at virtual targets increased grip aperture, slowed the velocity of the reach, and reduced the slopes relating grip aperture to the widths of the target. Thus, using the mirror has real consequences on grasp kinematics, reflecting the importance of task-relevant sources of online visual information for the programming and updating of natural prehensile movements. Taken together, these results provide compelling support for the view that removing terminal tactile feedback, even when the grasps are target-directed, induces a switch from real-time visual control towards one that depends more on visual perception and cognitive supervision. Providing terminal tactile feedback and real-time visual information can evidently keep the dorsal visuomotor system operating normally for prehensile acts.

Short-term blueberry-enriched antioxidant diet prevents and reverses object recognition memory loss in aged rats

USDA-ARS?s Scientific Manuscript database

Objective Previously, four months of a blueberry-enriched (BB) antioxidant diet prevented impaired object recognition memory in aged rats. Experiment 1 determined whether one and two-month BB diets would have a similar effect and whether the benefits would disappear promptly after terminating the d...

Curriculum Guide for Teachers of Educable Mentally Retarded -- Junior-Senior.

ERIC Educational Resources Information Center

Palm Beach County Board of Public Instruction, West Palm Beach, FL.

General behavioral objectives are listed for both junior and senior high level educables; unit and lesson plans on job safety and budgeting are provided; a unit on voice and diction is included. Over half of the document presents behavioral objectives, arranged according to general objectives, and lists terminal behavior, communicative and…

Effects of Case Manager Feedback on the Quality of Individual Habilitation Plan Objectives.

ERIC Educational Resources Information Center

Horner, Robert H.; And Others

1990-01-01

The functional relation between feedback and improved writing of Individual Habilitation Plan objectives in four adult service agencies serving the retarded was assessed. The agencies improved the quality of their written objectives after receiving feedback from the case manager and maintained those gains 18 months after feedback was terminated.…

Connective Tissue Growth Factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells

PubMed Central

MARKIEWICZ, MAGARET; NAKERAKANTI, SASHIDHAR S.; KAPANADZE, BAGRAT; GHATNEKAR, ANGELA; TROJANOWSKA, MARIA

2010-01-01

Objective The primary objective of this study was to examine the potential interaction between sphingosine-1-phosphate (S1P), a pleiotropic lipid mediator, and CTGF/CCN2 a secreted multimodular protein, in the process of endothelial cell migration. The second objective was to determine whether C- and N-terminal domains of CTGF/CCN2 have specific function in cell migration. Materials and Methods Migration of human dermal microvascular endothelial cells (HDMECs) was examined in monolayer wound healing “scratch” assay, while capillary-like tube formation was examined in 3 dimensional collagen co-culture assays. Results We observed that S1P stimulates HDMECs migration concomitant with upregulation of CTGF/CCN2 expression. Furthermore, the blockade of endogenous CTGF/CCN2 via siRNA abrogated S1P induced HDMECs migration and capillary-like tube formation. Full length CTGF induced cell migration and capillary-like tube formation with potency similar to that of S1P, while C-terminal domain of CTGF was slightly less effective. However; N-terminal domain had only a residual activity in inducing capillary-like tube formation. Conclusions This study revealed that CTGF/CCN2 is required for the S1P induced endothelial cell migration, which suggests that CTGF/CCN2 may be an important mediator of S1P induced physiological and pathological angiogenesis. Moreover, this study shows that the pro-migratory activity of CTGF/CCN2 is located in the C-terminal domain. PMID:21166920

Welding.

ERIC Educational Resources Information Center

Cowan, Earl; And Others

The curriculum guide for welding instruction contains 16 units presented in six sections. Each unit is divided into the following areas, each of which is color coded: terminal objectives, specific objectives, suggested activities, and instructional materials; information sheet; transparency masters; assignment sheet; test; and test answers. The…

Safety performance functions for ramp terminals at diamond interchanges.

DOT National Transportation Integrated Search

2011-07-01

This report documents two efforts to support CDOT in the area of Safety Performance Function (SPF) : development. The first involved the data collection and development of SPFs for five categories of ramp : terminals at diamond interchanges. For each...

40 CFR 60.502 - Standard for Volatile Organic Compound (VOC) emissions from bulk gasoline terminals.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (VOC) emissions from bulk gasoline terminals. 60.502 Section 60.502 Protection of Environment... SOURCES Standards of Performance for Bulk Gasoline Terminals § 60.502 Standard for Volatile Organic Compound (VOC) emissions from bulk gasoline terminals. On and after the date on which § 60.8(a) requires a...

40 CFR 60.502 - Standard for Volatile Organic Compound (VOC) emissions from bulk gasoline terminals.

Code of Federal Regulations, 2012 CFR

2012-07-01

... (VOC) emissions from bulk gasoline terminals. 60.502 Section 60.502 Protection of Environment... SOURCES Standards of Performance for Bulk Gasoline Terminals § 60.502 Standard for Volatile Organic Compound (VOC) emissions from bulk gasoline terminals. On and after the date on which § 60.8(a) requires a...

40 CFR 60.502 - Standard for Volatile Organic Compound (VOC) emissions from bulk gasoline terminals.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (VOC) emissions from bulk gasoline terminals. 60.502 Section 60.502 Protection of Environment... SOURCES Standards of Performance for Bulk Gasoline Terminals § 60.502 Standard for Volatile Organic Compound (VOC) emissions from bulk gasoline terminals. On and after the date on which § 60.8(a) requires a...

40 CFR 60.502 - Standard for Volatile Organic Compound (VOC) emissions from bulk gasoline terminals.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (VOC) emissions from bulk gasoline terminals. 60.502 Section 60.502 Protection of Environment... SOURCES Standards of Performance for Bulk Gasoline Terminals § 60.502 Standard for Volatile Organic Compound (VOC) emissions from bulk gasoline terminals. On and after the date on which § 60.8(a) requires a...

40 CFR 60.502 - Standard for Volatile Organic Compound (VOC) emissions from bulk gasoline terminals.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (VOC) emissions from bulk gasoline terminals. 60.502 Section 60.502 Protection of Environment... SOURCES Standards of Performance for Bulk Gasoline Terminals § 60.502 Standard for Volatile Organic Compound (VOC) emissions from bulk gasoline terminals. On and after the date on which § 60.8(a) requires a...

The Development, Field Testing and Evaluation of Three Hierarchies of Behaviorally Stated Objectives for the Chemistry Content of a Course of Instruction in Physical Science for Pre-Service Nursing Students.

ERIC Educational Resources Information Center

Love, Robert Alden

The purpose of this research was to develop hierarchies of behavioral objectives for the chemistry content of a one-semester course in physical science for preservice associate degree nursing students. Each of three content objectives was expressed by a series of behaviorally stated objectives which included a terminal objective for a unit of…

Basic Learning Skills Grades K-6. Minimum Statewide Educational Objectives Approved by the Board of Education May 27, 1977.

ERIC Educational Resources Information Center

Virginia State Dept. of Education, Richmond. Div. of Elementary Education.

The specific educational objectives or basic learning skills are listed for the Virginia elementary school grades. Minimum skills are listed in reading, communications, and mathematics. Terminal objectives for reading include skills in word identification or decoding, comprehension, and study skills. Communication skills include listening,…

“Having Another Child Would Be a Life or Death Situation for Her”: Understanding Pregnancy Termination Among Couples in Rural Bangladesh

PubMed Central

Hindin, Michelle J.

2008-01-01

Objectives. We conducted a mixed-method study in rural southwestern Bangladesh, a country in which an estimated 730 000 elective pregnancy terminations occur each year, to explore women's and couples’ motivations to terminate pregnancies. Methods. Quantitative data derived from a 1998 cross-sectional survey and a longitudinal demographic surveillance system (1998–2003) were combined with qualitative data gathered through 84 in-depth interviews conducted with 19 couples during 2004–2005. Results. Quantitative results indicated that 11% of couples reported a pregnancy termination in the study period; the rate was highest among couples who reported in 1998 that they wanted no more children (29%). Both wives’ and husbands’ fertility preferences independently and significantly predicted pregnancy termination. Qualitative findings showed that more than half of the participants had attempted to terminate a pregnancy at least once in their lifetime. Conclusions. Our results highlight the importance of collecting data from both partners and the influence of husbands’ fertility preferences on reproductive decisionmaking. The prevalence of reported pregnancy terminations in our population, along with the use of informal methods in termination attempts, highlights the need for continued provision of contraceptives and access to safe and affordable pregnancy termination services in this setting. PMID:18703439

48 CFR 32.109 - Termination financing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Termination financing. 32... CONTRACTING REQUIREMENTS CONTRACT FINANCING Non-Commercial Item Purchase Financing 32.109 Termination financing. To encourage contractors to invest their own funds in performance despite the susceptibility of...

Electrokinetic supercharging with a system-induced terminator and an optimized capillary versus electrode configuration for parts-per-trillion detection of rare-earth elements in CZE.

PubMed

Xu, Zhongqi; Kawahito, Kouji; Ye, Xiaoxue; Timerbaev, Andrei R; Hirokawa, Takeshi

2011-05-01

A further improvement of electrokinetic supercharging (EKS) methodology has been proposed, with the objective to enhance the sensitivity of the conventional CZE-UV method down to a single-digit part per trillion (ppt) level. The advanced EKS procedure is based on a novel phenomenon displaying the formation of a zone with an increased concentration of the hydrogen ion, capable to perform the function of a terminator, behind the sample zone upon electrokinetic injection. In combination with a visualizing co-ion of BGE, protonated 4-methylbenzylamine, acting as the leading ion, such system-induced terminator a effected the transient ITP state to efficiently concentrate cationic analytes prior to CZE. Furthermore, to amass more analyte ions within the effective electric field at the injection stage, a standard sample vial was replaced with an elongated vial that allowed the sample volume to be increased from 500 to 900 μL. Alongside, this replacement made the upright distance between the electrode and the capillary tips prolonged to 40.0 mm to achieve high-efficiency electrokinetic injection. The computer simulation was used for profiling analyte concentration, pH, and field strength in order to delineate formation of the terminator during sample injection. The proposed preconcentration strategy afforded an enrichment factor of 80,000 and thereby the LODs of rare-earth metal ions at the ppt level, e.g. 0.04 nM (6.7 ng/L) for erbium(III). Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Effects and safety of mechanical bathing as a complementary therapy for terminal stage cancer patients from the physiological and psychological perspective: a pilot study.

PubMed

Fujimoto, Sawako; Iwawaki, Yoko; Takishita, Yukie; Yamamoto, Yoko; Murota, Masako; Yoshioka, Saori; Hayano, Azusa; Hosokawa, Toyoshi; Yamanaka, Ryuya

2017-11-01

In palliative care hospitals in Japan, mechanical bathing is conducted to maintain cleanliness. However, the physiological and psychological influence of mechanical bathing on patients has not been sufficiently studied. The objective of this study was to assess, using physiological and psychological indices, the effects of mechanical bathing care for patients in the terminal stage of cancer. Mechanical bathing was performed using a Marine Court SB7000 in a supine or semi-seated position. The heart rate variability analysis method was used to measure autonomic nervous system function. The patients' state of anxiety was assessed using the State-Trait Anxiety Inventory (STAI), a psychological index, and patients' verbal responses were also collected after mechanical bathing. Twenty-four patients were enrolled in this study. Their sympathetic and parasympathetic nervous activity did not differ before and after bathing. A significant difference was found between pre- and post-bathing anxiety, as evaluated by STAI (P < 0.0001). In the patient's verbal responses that was collected, the most frequently mentioned descriptors were 'comfortable' and 'relaxed'. Patients were more relaxed after mechanical bathing according to STAI evaluation and their verbal responses. The findings suggest that the method of bathing used in this study is safe and pain-relieving for terminal stage cancer patients. It is thus possible to provide safe and comfortable care for terminal stage cancer patients using mechanical baths. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

Alkynyl-Containing Peptides of Marine Origin: A Review

PubMed Central

Chai, Qiu-Ye; Yang, Zhen; Lin, Hou-Wen; Han, Bing-Nan

2016-01-01

Since the 1990s, a number of terminal alkynyl residue-containing cyclic/acyclic peptides have been identified from marine organisms, especially cyanobacteria and marine mollusks. This review has presented 66 peptides, which covers over 90% marine peptides with terminal alkynyl fatty acyl units. In fact, more than 90% of these peptides described in the literature are of cyanobacterial origin. Interestingly, all the linear peptides featured with terminal alkyne were solely discovered from marine cyanobacteria. The objective of this article is to provide an overview on the types, structural characterization of these unusual terminal alkynyl fatty acyl units, as well as the sources and biological functions of their composed peptides. Many of these peptides have a variety of biological activities, including antitumor, antibacterial, antimalarial, etc. Further, we have also discussed the evident biosynthetic origin responsible for formation of terminal alkynes of natural PKS (polyketide synthase)/NRPS (nonribosome peptide synthetase) hybrids. PMID:27886049

Development of mini VSAT system

NASA Astrophysics Data System (ADS)

Lu, Shyue-Ching; Chiu, Wu-Jhy; Lin, Hen-Dao; Shih, Mu-Piao

1992-03-01

This paper presents the mini VSAT (very small aperture terminal) system, which is a low cost networking system providing economical alternatives to the business world's datacom needs. The system is designed to achieve the highest possible performance/price ratio for private VSAT networks that range from a few tens of remote terminals to large networks of several thousands remote terminals. The paper describes the system architecture, major features, hardware and software structure, access protocol and performance of the developed system.

Development of the multiwavelength monolithic integrated fiber optics terminal

NASA Technical Reports Server (NTRS)

Chubb, C. R.; Bryan, D. A.; Powers, J. K.; Rice, R. R.; Nettle, V. H.; Dalke, E. A.; Reed, W. R.

1982-01-01

This paper describes the development of the Multiwavelength Monolithic Integrated Fiber Optic Terminal (MMIFOT) for the NASA Johnson Space Center. The program objective is to utilize guided wave optical technology to develop wavelength-multiplexing and -demultiplexing units, using a single mode optical fiber for transmission between terminals. Intensity modulated injection laser diodes, chirped diffraction gratings and thin film lenses are used to achieve the wavelength-multiplexing and -demultiplexing. The video and audio data transmission test of an integrated optical unit with a Luneburg collimation lens, waveguide diffraction grating and step index condensing lens is described.

Injury Outcome in Crashes with Guardrail End Terminals.

PubMed

Johnson, Nicholas S; Gabler, Hampton C

2015-01-01

The goal of this study is to evaluate the crash performance of guardrail end terminals in real-world crashes. Guardrail end terminals are installed at the ends of guardrail systems to prevent the rail from spearing through the car in an end-on collision. Recently, there has been a great deal of controversy as to the safety of certain widely used end terminal designs, partly because there is surprisingly little real-world crash data for end terminals. Most existing studies of end terminal crashes used data from prior to the mid-1990s. Since then, there have been large improvements to vehicle crashworthiness and seat belt usage rates, as well as new roadside safety hardware compliant with National Cooperative Highway Research Program (NCHRP) Report 350, "Recommended Procedures for the Safety Performance Evaluation of Highway Features." Additionally, most existing studies of injury in end terminal crashes do not account for factors such as the occurrence of rollover. This analysis uses more recent crash data that represent post-1990s vehicle fleet changes and account for a number of factors that may affect driver injury outcome and rollover occurrence. Passenger vehicle crashes coded as involving guardrail end terminals were identified in the set of police-reported crashes in Michigan in 2011 and 2012. End terminal performance was expected to be a function of end terminal system design. State crash databases generally do not identify specific end terminal systems. In this study, the coded crash location was used to obtain photographs of the crash site prior to the crash from Google Street View. These site photographs were manually inspected to identify the particular end terminal system involved in the crash. Multiple logistic regression was used to test for significant differences in the odds of driver injury and rollover between different terminal types while accounting for other factors. A total of 1,001 end terminal crashes from the 2011-2012 Michigan State crash data were manually inspected to identify the terminal that had been struck. Four hundred fifty-one crashes were found to be suitable for analysis. Serious to fatal driver injury occurred in 3.8% of end terminal crashes, moderate to fatal driver injury occurred in 11.8%, and 72.3% involved property damage only. No significant difference in moderate to fatal driver injury odds was observed between NCHRP 350 compliant end terminals and noncompliant terminals. Car drivers showed odds of moderate to fatal injury 3.6 times greater than LTV drivers in end terminal crashes. Rollover occurrence was not significantly associated with end terminal type. Car drivers have greater potential for injury in end terminal crashes than light truck/van/sport utility vehicle drivers. End terminal designs compliant with NCHRP 350 did not appear to carry different odds of moderate driver injury than noncompliant end terminals. The findings account for driver seat belt use, rollover occurrence, terminal orientation (leading/trailing), control loss, and the number of impact events. Rollover and nonuse of seat belts carried much larger increases in injury potential than end terminal type. Rollover did not appear to be associated with NCHRP 350 compliance.

Terminal Dynamics Approach to Discrete Event Systems

NASA Technical Reports Server (NTRS)

Zak, Michail; Meyers, Ronald

1995-01-01

This paper presents and discusses a mathematical formalism for simulation of discrete event dynamic (DED)-a special type of 'man-made' systems to serve specific purposes of information processing. The main objective of this work is to demonstrate that the mathematical formalism for DED can be based upon a terminal model of Newtonian dynamics which allows one to relax Lipschitz conditions at some discrete points.!.

Evaluation of Columbia, USMARC-Composite, Suffolk, and Texel rams as terminal sires in an extensive rangeland production system: I. Ewe productivity and crossbred lamb survival and preweaning growth

USDA-ARS?s Scientific Manuscript database

A 3-yr study was conducted to comprehensively evaluate Columbia, Suffolk, USMARC-Composite (Composite), and Texel breeds as terminal sires in an extensive rangeland production system. The objective was to estimate breed-of-ram effects on ewe fertility, prolificacy, and dystocia, and sire breed effe...

Performance evaluation type II and type IIA box beam end terminals--volume II : appendices.

DOT National Transportation Integrated Search

2010-01-10

Two types of guide rail end terminals were constructed and evaluated according to the American Association of State Highway : and Transportation Officials (AASHTOs) Manual for Assessing Safety Hardware (MASH). The guide rail end terminals are u...

Identification of key factors in consumers' adoption behavior of intelligent medical terminals based on a hybrid modified MADM model for product improvement.

PubMed

Liu, Yupeng; Chen, Yifei; Tzeng, Gwo-Hshiung

2017-09-01

As a new application technology of the Internet of Things (IoT), intelligent medical treatment has attracted the attention of both nations and industries through its promotion of medical informatisation, modernisation, and intelligentisation. Faced with a wide variety of intelligent medical terminals, consumers may be affected by various factors when making purchase decisions. To examine and evaluate the key influential factors (and their interrelationships) of consumer adoption behavior for improving and promoting intelligent medical terminals toward achieving set aspiration level in each dimension and criterion. A hybrid modified Multiple Attribute Decision-Making (MADM) model was used for this study, based on three components: (1) the Decision-Making Trial and Evaluation Laboratory (DEMATEL) technique, to build an influential network relationship map (INRM) at both 'dimensions' and 'criteria' levels; (2) the DEMATEL-based analytic network process (DANP) method, to determine the interrelationships and influential weights among the criteria and identify the source-influential factors; and (3) the modified Vlse Kriterijumska Optimizacija I Kompromisno Resenje (VIKOR) method, to evaluate and improve for reducing the performance gaps to meet the consumers' needs for continuous improvement and sustainable products-development. First, a consensus on the influential factors affecting consumers' adoption of intelligent medical terminals was collected from experts' opinion in practical experience. Next, the interrelationships and influential weights of DANP among dimensions/criteria based on the DEMATEL technique were determined. Finally, two intelligent medicine bottles (AdhereTech, A 1 alternative; and Audio/Visual Alerting Pillbox, A 2 alternative) were reviewed as the terminal devices to verify the accuracy of the MADM model and evaluate its performance on each criterion for improving the total certification gaps by systematics according to the modified VIKOR method based on an INRM. In this paper, the criteria and dimensions used to improve the evaluation framework are validated. The systematic evaluation in index system is constructed on the basis of five dimensions and corresponding ten criteria. Influential weights of all criteria ranges from 0.037 to 0.152, which shows the rank of criteria importance. The evaluative framework were validated synthetically and scientifically. INRM (influential network relation map) was obtained from experts' opinion through DEMATEL technique shows complex interrelationship among factors. At the dimension level, the environmental dimension influences other dimensions the most, whereas the security dimension is most influenced by others. So the improvement order of environmental dimension is prior to security dimension. The newly constructed approach was still further validated by the results of the empirical case, where performance gap improvement strategies were analyzed for decision-makers. The modified VIKOR method was especially validated for solving real-world problems in intelligent medical terminal improvement processes. For this paper, A 1 performs better than A 2 , however, promotion mix, brand factor, and market environment are shortcomings faced by both A 1 and A 2 . In addition, A 2 should be improved in the wireless network technology, and the objective contact with a high degree of gaps. Based on the evaluation index system and the integrated model proposed here, decision-makers in enterprises can identify gaps when promoting intelligent medical terminals, from which they can get valuable advice to improve consumer adoption. Additionally, an INRM and the influential weights of DANP can be combined using the modified VIKOR method as integrated weightings to determine how to reduce gaps and provide the best improvement strategies for reaching set aspiration levels. Copyright © 2017 Elsevier B.V. All rights reserved.

Transport in a field aligned magnetized plasma/neutral gas boundary: the end of the plasma

NASA Astrophysics Data System (ADS)

Cooper, Christopher Michael

The objective of this dissertation is to characterize the physics of a boundary layer between a magnetized plasma and a neutral gas along the direction of a confining magnetic field. A series of experiments are performed at the Enormous Toroidal Plasma Device (ETPD) at UCLA to study this field aligned Neutral Boundary Layer (NBL) at the end of the plasma. A Lanthanum Hexaboride (LaB6) cathode and semi-transparent anode creates a magnetized, current-free helium plasma which terminates on a neutral helium gas without touching any walls. Probes are inserted into the plasma to measure the basic plasma parameters and study the transport in the NBL. The experiment is performed in the weakly ionized limit where the plasma density (ne) is much less than the neutral density (nn) such that ne/nn < 5%. The NBL is characterized by a field-aligned electric field which begins at the point where the plasma pressure equilibrates with the neutral gas pressure. Beyond the pressure equilibration point the electrons and ions lose their momentum by collisions with the neutral gas and come to rest. An electric field is established self consistently to maintain a current-free termination through equilibration of the different species' stopping rates in the neutral gas. The electric field resembles a collisional quasineutral sheath with a length 10 times the electron-ion collision length, 100 times the neutral collision length, and 10,000 times the Debye length. Collisions with the neutral gas dominate the losses in the system. The measured plasma density loss rates are above the classical cross-field current-free ambipolar rate, but below the anomalous Bohm diffusion rate. The electron temperature is below the ionization threshold of the gas, 2.2 eV in helium. The ions are in thermal equilibrium with the neutral gas. A generalized theory of plasma termination in a Neutral Boundary Layer is applied to this case using a two-fluid, current-free, weakly ionized transport model. The electron and ion momentum equations along the field are combined in a generalized Ohm's law which predicts the axial electric field required to maintain a current-free termination. The pressure balance criteria for termination and the predicted electric field are confirmed over a scaling of plasma parameters. The experiment and the model are relevant for studying NBLs in other systems, such as the atmospheric termination of the aurora or detached gaseous divertors. A steady state modified ambipolar system is measured in the ETPD NBL. The drift speeds associated with these currents are a small fraction of the plasma flow speeds and the problem is treated as a perturbation to the termination model. The current-free condition on the model is relaxed to explain the presence of the divergence free current.

Two Unipolar Terminal-Attractor-Based Associative Memories

NASA Technical Reports Server (NTRS)

Liu, Hua-Kuang; Wu, Chwan-Hwa

1995-01-01

Two unipolar mathematical models of electronic neural network functioning as terminal-attractor-based associative memory (TABAM) developed. Models comprise sets of equations describing interactions between time-varying inputs and outputs of neural-network memory, regarded as dynamical system. Simplifies design and operation of optoelectronic processor to implement TABAM performing associative recall of images. TABAM concept described in "Optoelectronic Terminal-Attractor-Based Associative Memory" (NPO-18790). Experimental optoelectronic apparatus that performed associative recall of binary images described in "Optoelectronic Inner-Product Neural Associative Memory" (NPO-18491).

17 CFR 250.89 - Termination of contracts.

Code of Federal Regulations, 2011 CFR

2011-04-01

...) GENERAL RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Service, Sales and Construction Contracts § 250.89 Termination of contracts. Every service, sales, or construction contract made after April... contain provision for its termination to the extent that performance may conflict with any rule...

17 CFR 250.89 - Termination of contracts.

Code of Federal Regulations, 2010 CFR

2010-04-01

...) GENERAL RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Service, Sales and Construction Contracts § 250.89 Termination of contracts. Every service, sales, or construction contract made after April... contain provision for its termination to the extent that performance may conflict with any rule...

48 CFR 609.405-70 - Termination action decision.

Code of Federal Regulations, 2010 CFR

2010-10-01

...) For overseas posts, A/OPE. (b) Termination for default. Termination for default under a contract's default clause is appropriate when the circumstances giving rise to the debarment or suspension also constitute a default in the contractor's performance of that contract. Debarment or suspension of the...

Differences between terminally ill cancer patients who died after euthanasia had been performed and terminally ill cancer patients who did not request euthanasia.

PubMed

Georges, Jean-Jacques; Onwuteaka-Philipsen, Bregje D; van der Wal, Gerrit; van der Heide, Agnes; van der Maas, Paul J

2005-12-01

Palliative care, directed at improving the quality of life of terminally ill patients, is generally not aimed at any form of postponing or hastening death. It is possible that high quality palliative care could prevent requests for euthanasia. However, empirical evidence on this issue is scarce. In a national survey of end-of-life medical decisions in The Netherlands the subject of care at the end of life has been addressed. Data on terminally ill cancer patients who died after their request was granted and euthanasia had been performed were compared with those of terminally ill cancer patients who did not request euthanasia. The results show that the prevalence and severity of symptoms e.g., pain, feeling unwell, nausea, was higher in patients who died after their request was granted and euthanasia had been performed. No differences concerning the treatment of symptoms or the care provided were found between the two groups. The results suggest that the practice of euthanasia is mainly related to the patient's suffering.

Conjoined twins and legal authorization for abortion.

PubMed

Nomura, Roseli Mieko Yamamoto; Brizot, Maria de Lourdes; Liao, Adolfo Wenjaw; Hernandez, Wagner Rodrigues; Zugaib, Marcelo

2011-01-01

To describe pregnancies with conjoined twins according to the request for legal termination of pregnancy. Retrospective review of pregnancies with conjoined twins, with no possibility of extrauterine survival or postnatal surgical separation, observed at a tertiary teaching hospital, between 1998 and 2010. Amongst 30 cases seen during the study period, six (20.0%) couples decided to continue with the pregnancy, termination of pregnancy was not requested due to advanced gestational age (> 25 weeks) in 5 cases (16.7%). Legal authorization to terminate the pregnancy was requested in 19 (63.3%) cases: permission was granted in 12 (63.2%), denied in five (26.3%) and information was missing in two (10.5%) cases. A successful vaginal delivery was performed in 83.3% of the cases undergoing termination of pregnancy and a cesarean section was performed in all the remaining cases (p < 0.01). In pregnancies with conjoined twins and without fetal prognosis, legal termination of the pregnancy is an alternative. Moreover, a successful vaginal delivery can be performed in most cases before the third trimester, further reducing maternal risks and parental suffering.

20 CFR 404.325 - The termination month.

Code of Federal Regulations, 2011 CFR

2011-04-01

... activity level and continue to do so throughout the 36 months following completion of your trial work... third month following the earliest month you perform substantial gainful activity or are determined able to perform substantial gainful activity; however, in no event will the termination month under these...

20 CFR 404.325 - The termination month.

Code of Federal Regulations, 2010 CFR

2010-04-01

... activity level and continue to do so throughout the 36 months following completion of your trial work... third month following the earliest month you perform substantial gainful activity or are determined able to perform substantial gainful activity; however, in no event will the termination month under these...

Optoelectronic Terminal-Attractor-Based Associative Memory

NASA Technical Reports Server (NTRS)

Liu, Hua-Kuang; Barhen, Jacob; Farhat, Nabil H.

1994-01-01

Report presents theoretical and experimental study of optically and electronically addressable optical implementation of artificial neural network that performs associative recall. Shows by computer simulation that terminal-attractor-based associative memory can have perfect convergence in associative retrieval and increased storage capacity. Spurious states reduced by exploiting terminal attractors.

46 CFR 525.1 - Purpose and scope.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., warehouse or other terminal facilities in connection with a common carrier, or in connection with a common...; common carriers who perform port terminal services; and warehousemen who operate port terminal facilities... storage spaces, cold storage plants, cranes, grain elevators and/or bulk cargo loading and/or unloading...

Performance evaluation of type II and type IIA box beam end terminals--volume I : research results and discussion.

DOT National Transportation Integrated Search

2010-01-20

Two types of guide rail end terminals were constructed and evaluated according to the American Association of State Highway : Transportation Officials (AASHTOs)Manual for Assessing Safety Hardware (MASH). The guide rail end terminals are used w...

Piloting considerations for terminal area operations of civil tiltwing and tiltrotor aircraft

NASA Technical Reports Server (NTRS)

Hindson, William S.; Hardy, Gordon H.; Tucker, George E.; Decker, William A.

1993-01-01

The existing body of research to investigate airworthiness, performance, handling, and operational requirements for STOL and V/STOL aircraft was reviewed for its applicability to the tiltrotor and tiltwing design concepts. The objective of this study was to help determine the needs for developing civil certification criteria for these aircraft concepts. Piloting tasks that were considered included configuration and thrust vector management, glidepath control, deceleration to hover, and engine failure procedures. Flight control and cockpit display systems that have been found necessary to exploit the low-speed operating characteristics of these aircraft are described, and beneficial future developments are proposed.

Selective Reduction: "A Soft Cover for Hard Choices" or Another Name for Abortion?

PubMed

Rao, Radhika

2015-01-01

Selective reduction and abortion both involve the termination of fetal life, but they are classified by different designations to underscore the notion that they are regarded as fundamentally different medical procedures: the two are performed using distinct techniques by different types of physicians, upon women under very different circumstances, in order to further dramatically different objectives. Hence, the two procedures appear to call for a distinct moral calculus, and they have traditionally evoked contradictory reactions from society. This essay posits that despite their different appellations, selective reduction and abortion are essentially equivalent. © 2015 American Society of Law, Medicine & Ethics, Inc.

Formulation and evaluation of biodegradable nanoparticles for the oral delivery of fenretinide.

PubMed

Graves, Richard A; Ledet, Grace A; Glotser, Elena Y; Mitchner, Demaurian M; Bostanian, Levon A; Mandal, Tarun K

2015-08-30

Fenretinide is an anticancer drug with low water solubility and poor bioavailability. The goal of this study was to develop biodegradable polymeric nanoparticles of fenretinide with the intent of increasing its apparent aqueous solubility and intestinal permeability. Three biodegradable polymers were investigated for this purpose: two different poly lactide-co-glycolide (PLGA) polymers, one acid terminated and one ester terminated, and one poly lactide-co-glycolide/polyethylene glycol (PLGA/PEG) diblock copolymer. Nanoparticles were obtained by using an emulsification solvent evaporation technique. The formulations were characterized by differential scanning calorimetry (DSC), scanning electron microscopy (SEM), and particle size analysis. Dissolution studies and Caco-2 cell permeation studies were also carried out for all formulations. Ultra high performance liquid chromatography coupled with mass spectrometry (UPLC/MS) and ultraviolet detection was used for the quantitative determination of fenretinide. Drug loading and the type of polymer affected the nanoparticles' physical properties, drug release rate, and cell permeability. While the acid terminated PLGA nanoparticles performed the best in drug release, the ester terminated PLGA nanoparticles performed the best in the Caco-2 cell permeability assays. The PLGA/PEG copolymer nanoparticles performed better than the formulations with ester terminated PLGA in terms of drug release but had the poorest performance in terms of cell permeation. All three categories of formulations performed better than the drug alone in both drug release and cell permeation studies. Copyright © 2015 Elsevier B.V. All rights reserved.

Aging and the Shape of Cognitive Change Before Death: Terminal Decline Or Terminal Drop?

PubMed Central

Hultsch, David F.; Dixon, Roger A.

2011-01-01

Objectives. Relative to typical age-related cognitive decrements, the terms “terminal decline” and “terminal drop” refer to the phenomenon of increased cognitive decline in proximity to death. Given that these terms are not necessarily synonymous, we examined the important theoretical distinction between the two alternative trajectories or shapes of changes they imply. Methods. We used 12-year (5-wave) data from the Victoria Longitudinal Study to directly test whether pre-death cognitive decrements follow a terminal decline (generally gradual) or a terminal drop (more abrupt) shape. Pre-death trajectories of cognitive decline for n = 265 decedents (Mage = 72.67 years, SD = 6.44) were examined separately for 5 key cognitive constructs (verbal speed, working memory, episodic memory, semantic memory, and crystallized ability). Results. Several classes of linear mixed models evaluated whether cognitive decline increased per additional year closer to death. Findings indicated that the shape of pre-death cognitive change was predominantly characterized by decline that is steeper as compared with typical aging-related change, but still best described as slow and steady decline, especially as compared with precipitous drop. Discussion. The present findings suggest that terminal decline and terminal drop trajectories may not be mutually exclusive but could rather reflect distinct developmental trajectories within the same individual. PMID:21300703

JOVIAL/Ada Microprocessor Study.

DTIC Science & Technology

1982-04-01

Study Final Technical Report interesting feature of the nodes is that they provide multiple virtual terminals, so it is possible to monitor several...Terminal Interface Tasking Except ion Handling A more elaborate system could allow such features as spooling, background jobs or multiple users. To a large...Another editor feature is the buffer. Buffers may hold small amounts of text or entire text objects. They allow multiple files to be edited simultaneously

Rapid incorporation kinetics and improved fidelity of a novel class of 3'-OH unblocked reversible terminators.

PubMed

Gardner, Andrew F; Wang, Jinchun; Wu, Weidong; Karouby, Jennifer; Li, Hong; Stupi, Brian P; Jack, William E; Hersh, Megan N; Metzker, Michael L

2012-08-01

Recent developments of unique nucleotide probes have expanded our understanding of DNA polymerase function, providing many benefits to techniques involving next-generation sequencing (NGS) technologies. The cyclic reversible termination (CRT) method depends on efficient base-selective incorporation of reversible terminators by DNA polymerases. Most terminators are designed with 3'-O-blocking groups but are incorporated with low efficiency and fidelity. We have developed a novel class of 3'-OH unblocked nucleotides, called Lightning Terminators™, which have a terminating 2-nitrobenzyl moiety attached to hydroxymethylated nucleobases. A key structural feature of this photocleavable group displays a 'molecular tuning' effect with respect to single-base termination and improved nucleotide fidelity. Using Therminator DNA polymerase, we demonstrate that these 3'-OH unblocked terminators exhibit superior enzymatic performance compared to two other reversible terminators, 3'-O-amino-TTP and 3'-O-azidomethyl-TTP. Lightning Terminators show maximum incorporation rates (k(pol)) that range from 35 to 45 nt/s, comparable to the fastest NGS chemistries, yet with catalytic efficiencies (k(pol)/K(D)) comparable to natural nucleotides. Pre-steady-state kinetic studies of thymidine analogs revealed that the major determinant for improved nucleotide selectivity is a significant reduction in k(pol) by >1000-fold over TTP misincorporation. These studies highlight the importance of structure-function relationships of modified nucleotides in dictating polymerase performance.

A Possible Role for End-Stopped V1 Neurons in the Perception of Motion: A Computational Model

PubMed Central

Zarei Eskikand, Parvin; Kameneva, Tatiana; Ibbotson, Michael R.; Burkitt, Anthony N.; Grayden, David B.

2016-01-01

We present a model of the early stages of processing in the visual cortex, in particular V1 and MT, to investigate the potential role of end-stopped V1 neurons in solving the aperture problem. A hierarchical network is used in which the incoming motion signals provided by complex V1 neurons and end-stopped V1 neurons proceed to MT neurons at the next stage. MT neurons are categorized into two types based on their function: integration and segmentation. The role of integration neurons is to propagate unambiguous motion signals arriving from those V1 neurons that emphasize object terminators (e.g. corners). Segmentation neurons detect the discontinuities in the input stimulus to control the activity of integration neurons. Although the activity of the complex V1 neurons at the terminators of the object accurately represents the direction of the motion, their level of activity is less than the activity of the neurons along the edges. Therefore, a model incorporating end-stopped neurons is essential to suppress ambiguous motion signals along the edges of the stimulus. It is shown that the unambiguous motion signals at terminators propagate over the rest of the object to achieve an accurate representation of motion. PMID:27741307

Concept of Operations for the Next Generation Air Transportation System, Version 2.0

DTIC Science & Technology

2007-06-13

SIDA )/airport operations area (AOA), [R-110] terminal perimeter, terminal airspace (security) • Landside. Terminal public and commercial roadways and...Required Surveillance Performance RTSS Remote Terminal Security Screening SAA Special Activity Airspace SIDA Security Identification Display Area SM...impede airside operations? R-110 Research 6.4.2/C. 4.4.1 Airside: Security Identification Display Area ( SIDA )/AOA R&D needed to develop and

12 CFR 367.6 - Causes for exclusion.

Code of Federal Regulations, 2010 CFR

2010-01-01

... default; or (2) The termination of such contract(s) for poor performance; or (3) A violation of the terms of a contract that would have resulted in a default or termination of the contract for poor... lack of integrity, or conspiracy to do the same; (l) The contractor's performance under previous...

Inquiry into terminal decline: five objectives for future study.

PubMed

Gerstorf, Denis; Ram, Nilam

2013-10-01

Notions of terminal decline propose that late-life change is primarily driven by processes closely tied to pathology and mortality rather than chronological age. We use the rationales of longitudinal research as outlined by Baltes and Nesselroade (Baltes, P., & Nesselroade, J. [1979]. History and rationale of longitudinal research. In J. R. Nesselroade & P. Baltes (Eds.), Longitudinal research in the study of behavior and development [pp. 1-39]. San Diego, CA: Academic Press) as a framework for organizing research on terminal decline. In doing so, we note that there are relatively robust descriptions of terminal decline across a variety of different domains, as well as the extent of interindividual differences in the levels of function, rates of change, and timing of terminal decline (research rationales 1 and 2). However, there is much more to learn about the interrelations among change in different domains, the underlying mechanisms of change, and the factors that contribute to interindividual differences in change (research rationales 3-5). Needed are new study designs and analytical models that better address the structural, temporal, and causal interrelations that contribute to and protect against terminal decline.

A Comparative Evaluation between Cheiloscopic Patterns and Terminal Planes in Primary Dentition

PubMed Central

Vignesh, R; Rekha, C Vishnu; Annamalai, Sankar; Norouzi, Parisa; Sharmin, Ditto

2017-01-01

Objective: To assess the correlation between different cheiloscopic patterns with the terminal planes in deciduous dentition. Materials and Methods: Three hundred children who are 3–6 years old with complete primary dentition were recruited, and the pattern of molar terminal plane was recorded in the pro forma. Lip prints of these children were recorded with lipstick-cellophane method, and the middle 10 mm of lower lip was analyzed for the lip print pattern as suggested by Sivapathasundharam et al. The pattern was classified based on Tsuchihashi and Suzuki classification. Results: Type II (branched) pattern was the most predominant cheiloscopic pattern. The predominant patterns which related to the terminal planes were as follows: Type IV (reticular) and Type V (irregular) pattern for mesial step, Type IV (reticular) pattern for distal step, and Type I (complete vertical) pattern for flush terminal plane. No significant relationship was obtained on gender comparison. Conclusion: Lip prints can provide an alternative to dermatoglyphics to predict the terminal plane in primary dentition. Further studies with larger sample size are required to provide an insight into its significant correlations. PMID:29326500

Photovoltaic module electrical termination design requirement study

NASA Technical Reports Server (NTRS)

Mosna, F. J., Jr.; Donlinger, J.

1980-01-01

Pertinent electrical termination attributes were identified and used in the development of selection criteria which included function, environmental durability, utility, manufacturing, code, and cost. Significant aspects of each criteria are discussed, and eight different types of terminations are ranked according to their performance in remote, residential, intermediate, and industrial applications.

75 FR 60258 - Federal Acquisition Regulation; Termination for Default Reporting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-29

... terminations for cause or default and defective cost or pricing data, into the Past Performance Information... defective cost or pricing data and terminations for cause or default into the FAPIIS module of the PPIRS... Pricing Information Comment: One respondent submitted two separate comments suggesting that defective...

Design of low SWaP optical terminals for free space optical communications

NASA Astrophysics Data System (ADS)

Shubert, P.; Cline, A.; McNally, J.; Pierson, R.

2017-02-01

Along with advantages in higher data rates, spectrum contention, and security, free space optical communications can provide size, weight, and power (SWaP) advantages over radio frequency (RF) systems. SWaP is always an issue in space systems and can be critical in applying free space optical communications to small satellite platforms. The system design of small space-based free space optical terminals with Gbps data rates is addressed. System architectures and requirements are defined to ensure the terminals are capable of acquisition, establishment and maintenance of a free space optical communications link. Design trades, identification of blocking technologies, and performance analyses are used to evaluate the practical limitations to terminal SWaP. Small terminal design concepts are developed to establish their practicality and feasibility. Techniques, such as modulation formats and capacity approaching encoding, are considered to mitigate the disadvantages brought by SWaP limitations, and performance as a function of SWaP is evaluated.

75 FR 3665 - Regulations under the Comprehensive Smokeless Tobacco Health Education Act; Termination of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-22

... event-related objects that display the brand name, logo, or selling message of smokeless tobacco... vehicles and other event-related objects bearing smokeless tobacco brand names, logos, or selling messages... using brand names, logos, or selling messages. Given these legislative and likely regulatory changes...

Latin Curriculum Guide.

ERIC Educational Resources Information Center

Lee, Agnes; Stevens, Patrick

This guide delineates the scope and sequence of Latin instruction in levels 1-3 in terms of behavioral objectives. Following a review of the Bloomington, Minnesota, school philosophy and a discussion of the design of foreign language behavioral objectives on which the guide is based, the manual discusses expected terminal behavior in the level 1…

An Elementary Algorithm for Autonomous Air Terminal Merging and Interval Management

NASA Technical Reports Server (NTRS)

White, Allan L.

2017-01-01

A central element of air traffic management is the safe merging and spacing of aircraft during the terminal area flight phase. This paper derives and examines an algorithm for the merging and interval managing problem for Standard Terminal Arrival Routes. It describes a factor analysis for performance based on the distribution of arrivals, the operating period of the terminal, and the topology of the arrival routes; then presents results from a performance analysis and from a safety analysis for a realistic topology based on typical routes for a runway at Phoenix International Airport. The heart of the safety analysis is a statistical derivation on how to conduct a safety analysis for a local simulation when the safety requirement is given for the entire airspace.

Interventions and decision-making at the end of life: the effect of establishing the terminal illness situation.

PubMed

Campos-Calderón, C; Montoya-Juárez, R; Hueso-Montoro, C; Hernández-López, E; Ojeda-Virto, F; García-Caro, M P

2016-11-07

Many 'routine' interventions performed in hospital rooms have repercussions for the comfort of the patient, and the decision to perform them should depend on whether the patient is identified as in a terminal phase. The aim of this study is to analyse the health interventions performed and decisions made in the last days of life in patients with advanced oncological and non-oncological illness to ascertain whether identifying the patient's terminal illness situation has any effect on these decisions. Retrospective study of the clinical histories of deceased patients in four hospitals in Granada (Spain) in 2010. Clinical histories corresponding to the last three months of the patient's life were reviewed. A total of 202 clinical histories were reviewed, 60 % of which were those of non-oncology patients. Opioid prescriptions (58.4 %), palliative sedation (35.1 %) and Do Not Resuscitate (DNR) orders (34.7 %) were the decisions most often reflected in the histories, and differences in these decisions were found between patients registered as terminal and those who were not registered as terminal. The most frequent interventions in the final 14 days and 48 h were parenteral hydration (96-83 %), peripheral venous catheter (90.1-82 %) and oxygen therapy (81.2-70.5 %). There were statistically significant differences between the patients who were registered as terminal and those not registered as terminal in the number of interventions applied in the final 14 days and 48 h (p = 0.01-p = 0.00) and in many of the described treatments. The recognition of a patient's terminal status in the clinical history conditions the decisions that are made and is generally associated with a lower number of interventions.

High prevalence of morphometric vertebral deformities in patients with inflammatory bowel disease.

PubMed

Heijckmann, Anna Caroline; Huijberts, Maya S P; Schoon, Erik J; Geusens, Piet; de Vries, Jolanda; Menheere, Paul P C A; van der Veer, Eveline; Wolffenbuttel, Bruce H R; Stockbrugger, Reinhold W; Dumitrescu, Bianca; Nieuwenhuijzen Kruseman, Arie C

2008-08-01

Earlier studies have documented that the prevalence of decreased bone mineral density (BMD) is elevated in patients with inflammatory bowel disease. The objective of this study was to investigate the prevalence of vertebral deformities in inflammatory bowel disease patients and their relation with BMD and bone turnover. One hundred and nine patients with Crohn's disease (CD) and 72 with ulcerative colitis (UC) (age 44.5+/-14.2 years) were studied. BMD of the hip (by dual X-ray absorptiometry) was measured and a lateral single energy densitometry of the spine for assessment of vertebral deformities was performed. Serum markers of bone resorption (carboxy-terminal cross-linked telopeptide of type I collagen) and formation (procollagen type I amino-terminal propeptide) were measured, and determinants of prevalent vertebral deformities were assessed using logistic regression analysis. Vertebral deformities were found in 25% of both CD and UC patients. Comparing patients with and without vertebral deformities, no significant difference was found between Z-scores and T-scores of BMD, or levels of serum carboxy-terminal cross-linked telopeptide of type I collagen and serum procollagen type I amino-terminal propeptide. Using logistic regression analysis the only determinant of any morphometric vertebral deformity was sex. The presence of multiple vertebral deformities was associated with older age and glucocorticoid use. The prevalence of morphometric vertebral deformities is high in CD and UC. Male sex, but neither disease activity, bone turnover markers, clinical risk factors, nor BMD predicted their presence. The determinants for having more than one vertebral deformity were age and glucocorticoid use. This implies that in addition to screening for low BMD, morphometric assessment of vertebral deformities is warranted in CD and UC.

Multistage Electrotherapy Delivered Through Chronically-Implanted Leads Terminates Atrial Fibrillation With Lower Energy Than a Single Biphasic Shock

PubMed Central

Janardhan, Ajit H.; Gutbrod, Sarah R.; Li, Wenwen; Lang, Di; Schuessler, Richard B.; Efimov, Igor R.

2014-01-01

Objectives The goal of this study was to develop a low-energy, implantable device–based multistage electrotherapy (MSE) to terminate atrial fibrillation (AF). Background Previous attempts to perform cardioversion of AF by using an implantable device were limited by the pain caused by use of a high-energy single biphasic shock (BPS). Methods Transvenous leads were implanted into the right atrium (RA), coronary sinus, and left pulmonary artery of 14 dogs. Self-sustaining AF was induced by 6 ± 2 weeks of high-rate RA pacing. Atrial defibrillation thresholds of standard versus experimental electrotherapies were measured in vivo and studied by using optical imaging in vitro. Results The mean AF cycle length (CL) in vivo was 112 ± 21 ms (534 beats/min). The impedances of the RA–left pulmonary artery and RA–coronary sinus shock vectors were similar (121 ± 11 Ω vs. 126 ± 9 Ω; p = 0.27). BPS required 1.48 ± 0.91 J (165 ± 34 V) to terminate AF. In contrast, MSE terminated AF with significantly less energy (0.16 ± 0.16 J; p < 0.001) and significantly lower peak voltage (31.1 ± 19.3 V; p < 0.001). In vitro optical imaging studies found that AF was maintained by localized foci originating from pulmonary vein–left atrium interfaces. MSE Stage 1 shocks temporarily disrupted localized foci; MSE Stage 2 entrainment shocks continued to silence the localized foci driving AF; and MSE Stage 3 pacing stimuli enabled consistent RA–left atrium activation until sinus rhythm was restored. Conclusions Low-energy MSE significantly reduced the atrial defibrillation thresholds compared with BPS in a canine model of AF. MSE may enable painless, device-based AF therapy. PMID:24076284

7 CFR 1494.801 - Enforcement and termination of agreements with CCC.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false Enforcement and termination of agreements with CCC... Enhancement Program Operations § 1494.801 Enforcement and termination of agreements with CCC. (a) Performance in accordance with an Agreement with CCC. (1) An exporter which enters into an Agreement with CCC...

7 CFR 1494.801 - Enforcement and termination of agreements with CCC.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 10 2013-01-01 2013-01-01 false Enforcement and termination of agreements with CCC... Enhancement Program Operations § 1494.801 Enforcement and termination of agreements with CCC. (a) Performance in accordance with an Agreement with CCC. (1) An exporter which enters into an Agreement with CCC...

7 CFR 1494.801 - Enforcement and termination of agreements with CCC.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false Enforcement and termination of agreements with CCC... Enhancement Program Operations § 1494.801 Enforcement and termination of agreements with CCC. (a) Performance in accordance with an Agreement with CCC. (1) An exporter which enters into an Agreement with CCC...

Distinct compartmentalization of dentin matrix protein 1 fragments in mineralized tissues and cells.

PubMed

Maciejewska, Izabela; Qin, Disheng; Huang, Bingzhen; Sun, Yao; Mues, Gabrielle; Svoboda, Kathy; Bonewald, Lynda; Butler, William T; Feng, Jerry Q; Qin, Chunlin

2009-01-01

Dentin matrix protein 1 (DMP1) has been shown to be critical for the formation of dentin and bone. However, the precise pathway by which DMP1 participates in dentinogenesis and osteogenesis remains to be clarified. DMP1 is present in the extracellular matrix of dentin and bone as processed NH(2)- and COOH-terminal fragments. The NH(2)-terminal fragment occurs as a proteoglycan, whereas the COOH-terminal fragment is highly phosphorylated. The differences in biochemical properties suggest that these fragments may have different tissue and cell distribution in association with distinct functions. In this study, we analyzed the distribution of the NH(2)- and COOH-terminal fragments of DMP1 in tooth, bone, osteocytes as well as MC3T3-E1 and HEK-293 cells. Immunohistochemical analyses were performed using antibodies specific to the NH(2)- or COOH-terminal region of DMP1. Clear differences in the distribution of these fragments were observed. In the teeth and bone, the NH(2)-terminal fragment was primarily located in the nonmineralized predentin and cartilage of the growth plate, while the COOH-terminal fragment accumulated in the mineralized zones. In osteocytes, the NH(2)-terminal fragment appeared more abundant along cell membrane and processes of osteocytes, while the COOH-terminal fragment was often found in the nuclei. This pattern of distribution in cellular compartments was further confirmed by analyses on MC3T3-E1 and HEK-293 cells transfected with a construct containing DMP1 cDNA. In these cell lines, the COOH-terminal fragment accumulated in cell nuclei, while the NH(2)-terminal fragment was in the cytosol. The different distribution of DMP1 fragments indicates that these DMP1 variants must perform distinct functions. Copyright 2008 S. Karger AG, Basel.

10 CFR 1706.7 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-01-01

... decline to approve performance of a particular task by the contractor if an actual or potential OCI is...) Terminate the contract, or, in the case of a task order contract, terminate the particular task; (ii) Insist... contractor to continue to perform the contract (or task) under the waiver provisions of § 1706.8, and, where...

Layered data association using graph-theoretic formulation with applications to tennis ball tracking in monocular sequences.

PubMed

Yan, Fei; Christmas, William; Kittler, Josef

2008-10-01

In this paper, we propose a multilayered data association scheme with graph-theoretic formulation for tracking multiple objects that undergo switching dynamics in clutter. The proposed scheme takes as input object candidates detected in each frame. At the object candidate level, "tracklets'' are "grown'' from sets of candidates that have high probabilities of containing only true positives. At the tracklet level, a directed and weighted graph is constructed, where each node is a tracklet, and the edge weight between two nodes is defined according to the "compatibility'' of the two tracklets. The association problem is then formulated as an all-pairs shortest path (APSP) problem in this graph. Finally, at the path level, by analyzing the APSPs, all object trajectories are identified, and track initiation and track termination are automatically dealt with. By exploiting a special topological property of the graph, we have also developed a more efficient APSP algorithm than the general-purpose ones. The proposed data association scheme is applied to tennis sequences to track tennis balls. Experiments show that it works well on sequences where other data association methods perform poorly or fail completely.

Conscientious objection or fear of social stigma and unawareness of ethical obligations.

PubMed

Faúndes, Anibal; Duarte, Graciana Alves; Osis, Maria José Duarte

2013-12-01

Conscientious objection is a legitimate right of physicians to reject the practice of actions that violate their ethical or moral principles. The application of that principle is being used in many countries as a justification to deny safe abortion care to women who have the legal right to have access to safe termination of pregnancy. The problem is that, often, this concept is abused by physicians who camouflage under the guise of conscientious objection their fear of experiencing discrimination and social stigma if they perform legal abortions. These colleagues seem to ignore the ethical principle that the primary conscientious duty of OB/GYNs is-at all times-to treat, or provide benefit and prevent harm to, the patients for whose care they are responsible. Any conscientious objection to treating a patient is secondary to this primary duty. One of the jobs of the FIGO Working Group for the Prevention of Unsafe Abortion is to change this paradigm and make our colleagues proud of providing legal abortion services that protect women's life and health, and concerned about disrespecting the human rights of women and professional ethical principles. Copyright © 2013 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

How do the outcomes of the DEKA Arm compare to conventional prostheses?

PubMed

Resnik, Linda J; Borgia, Matthew L; Acluche, Frantzy; Cancio, Jill M; Latlief, Gail; Sasson, Nicole

2018-01-01

Objectives were to 1) compare self-reported function, dexterity, activity performance, quality of life and community integration of the DEKA Arm to conventional prostheses; and 2) examine differences in outcomes by conventional prosthesis type, terminal device type and by DEKA Arm configuration level. This was a two-part study; Part A consisted of in-laboratory training. Part B consisted of home use. Study participants were 23 prosthesis users (mean age = 45 ± 16; 87% male) who completed Part A, and 15 (mean age = 45 ± 18; 87% male) who completed Parts A and B. Outcomes including self-report and performance measures, were collected at Baseline using participants' personal prostheses and at the End of Parts A and B. Scores were compared using paired t-tests. Wilcoxon signed-rank tests were used to compare outcomes for the full sample, and for the sample stratified by device and terminal device type. Analysis of outcomes by configuration level was performed graphically. At the End of Part A activity performance using the DEKA Arm and conventional prosthesis was equivalent, but slower with the DEKA Arm. After Part B, performance using the DEKA Arm surpassed conventional prosthesis scores, and speed of activity completion was equivalent. Participants reported using the DEKA Arm to perform more activities, had less perceived disability, and less difficulty in activities at the End of A and B as compared to Baseline. No differences were observed in dexterity, prosthetic skill, spontaneity, pain, community integration or quality of life. Comparisons stratified by device type revealed similar patterns. Graphic comparisons revealed variations by configuration level. Participants using the DEKA Arm had less perceived disability and more engagement of the prosthesis in everyday tasks, although activity performance was slower. After home use experience, activity performance was improved and activity speed equivalent to using conventional prostheses.

BDNF Expression in Perirhinal Cortex is Associated with Exercise-Induced Improvement in Object Recognition Memory

PubMed Central

Hopkins, Michael E.; Bucci, David J.

2010-01-01

Physical exercise induces widespread neurobiological adaptations and improves learning and memory. Most research in this field has focused on hippocampus-based spatial tasks and changes in brain-derived neurotrophic factor (BDNF) as a putative substrate underlying exercise-induced cognitive improvements. Chronic exercise can also be anxiolytic and causes adaptive changes in stress reactivity. The present study employed a perirhinal cortex-dependent object recognition task as well as the elevated plus maze to directly test for interactions between the cognitive and anxiolytic effects of exercise in male Long Evans rats. Hippocampal and perirhinal cortex tissue was collected to determine whether the relationship between BDNF and cognitive performance extends to this non-spatial and non-hippocampal-dependent task. We also examined whether the cognitive improvements persisted once the exercise regimen was terminated. Our data indicate that 4 weeks of voluntary exercise every-other-day improved object recognition memory. Importantly, BDNF expression in the perirhinal cortex of exercising rats was strongly correlated with object recognition memory. Exercise also decreased anxiety-like behavior, however there was no evidence to support a relationship between anxiety-like behavior and performance on the novel object recognition task. There was a trend for a negative relationship between anxiety-like behavior and hippocampal BDNF. Neither the cognitive improvements nor the relationship between cognitive function and perirhinal BDNF levels persisted after 2 weeks of inactivity. These are the first data demonstrating that region-specific changes in BDNF protein levels are correlated with exercise-induced improvements in non-spatial memory, mediated by structures outside the hippocampus and are consistent with the theory that, with regard to object recognition, the anxiolytic and cognitive effects of exercise may be mediated through separable mechanisms. PMID:20601027

Weight distributions for turbo codes using random and nonrandom permutations

NASA Technical Reports Server (NTRS)

Dolinar, S.; Divsalar, D.

1995-01-01

This article takes a preliminary look at the weight distributions achievable for turbo codes using random, nonrandom, and semirandom permutations. Due to the recursiveness of the encoders, it is important to distinguish between self-terminating and non-self-terminating input sequences. The non-self-terminating sequences have little effect on decoder performance, because they accumulate high encoded weight until they are artificially terminated at the end of the block. From probabilistic arguments based on selecting the permutations randomly, it is concluded that the self-terminating weight-2 data sequences are the most important consideration in the design of constituent codes; higher-weight self-terminating sequences have successively decreasing importance. Also, increasing the number of codes and, correspondingly, the number of permutations makes it more and more likely that the bad input sequences will be broken up by one or more of the permuters. It is possible to design nonrandom permutations that ensure that the minimum distance due to weight-2 input sequences grows roughly as the square root of (2N), where N is the block length. However, these nonrandom permutations amplify the bad effects of higher-weight inputs, and as a result they are inferior in performance to randomly selected permutations. But there are 'semirandom' permutations that perform nearly as well as the designed nonrandom permutations with respect to weight-2 input sequences and are not as susceptible to being foiled by higher-weight inputs.

Object Substitution Masking: When Does Mask Preview Work?

ERIC Educational Resources Information Center

Lim, Stephen Wee Hun; Chua, Fook K.

2008-01-01

When a target is enclosed by a 4-dot mask that persists after the target disappears, target identification is worse than it is when the mask terminates with the target. This masking effect is attributed to object substitution masking (OSM). Previewing the mask, however, attenuates OSM. This study investigated specific conditions under which mask…

Curriculum Outline for Introduction to Engineering Chemistry. First Edition. Review Cycle-Annual.

ERIC Educational Resources Information Center

Schlenker, Richard M.

This curriculum outline consists of behavioral objectives (called terminal and enabling objectives) for Introduction to Engineering Chemistry, a one-semester, post-secondary course consisting of four 1-hour lectures each week. Course goal is to introduce marine engineering students to the rudiments of basic/introductory inorganic chemistry. The…

A systematic assessment of drought termination in the United Kingdom

NASA Astrophysics Data System (ADS)

Parry, Simon; Wilby, Robert L.; Prudhomme, Christel; Wood, Paul J.

2016-10-01

Drought termination can be associated with dramatic transitions from drought to flooding. Greater attention may be given to these newsworthy and memorable events, but drought terminations that proceed gradually also pose challenges for water resource managers. This paper defines drought termination as a distinctive phase of the event. Using observed river flow records for 52 UK catchments, a more systematic and objective approach for detecting drought terminations is demonstrated. The parameters of the approach are informed by a sensitivity analysis that ensures a focus on terminations of multi-season to multi-year droughts. The resulting inventory of 467 drought terminations provides an unprecedented historical perspective on this phenomenon in the UK. Nationally and regionally coherent drought termination events are identifiable, although their characteristics vary both between and within major episodes. Contrasting drought termination events in 1995-1998 and 2009-2012 are examined in greater depth. The data are also used to assess potential linkages between metrics of drought termination and catchment properties. The duration of drought termination is moderately negatively correlated with elevation (rs = -0.47) and catchment average rainfall (rs = -0.42), suggesting that wetter catchments in upland areas of the UK tend to experience shorter drought terminations. More urbanized catchments tend to have gradual drought terminations (contrary to expectations of flashy hydrological response in such areas), although this may also reflect the type of catchments typical of lowland England. Significant correlations are found between the duration of the drought development phase and both the duration (rs = -0.29) and rate (rs = 0.28) of drought termination. This suggests that prolonged drought development phases tend to be followed by shorter and more abrupt drought terminations. The inventory helps to place individual events within a long-term context. The drought termination phase in 2009-2012 was, at the time, regarded as exceptional in terms of magnitude and spatial footprint, but the Thames river flow record identifies several comparable events before 1930. The chronology could, in due course, provide a basis for exploring the complex drivers, long-term variability, and impacts of drought termination events.

The terminal crest: morphological features relevant to electrophysiology

PubMed Central

Sánchez-Quintana, D; Anderson, R H; Cabrera, J A; Climent, V; Martin, R; Farré, J; Ho, S Y

2002-01-01

Objective: To investigate the detailed anatomy of the terminal crest (crista terminalis) and its junctional regions with the pectinate muscles and intercaval area to provide the yardstick for structural normality. Design: 97 human necropsy hearts were studied from patients who were not known to have medical histories of atrial arrhythmias. The dimensions of the terminal crest were measured in width and thickness from epicardium to endocardium, at the four points known to be chosen as sites of ablation. Results: The pectinate muscles originating from the crest and extending along the wall of the appendage towards the vestibule of the tricuspid valve had a non-uniform trabecular pattern in 80% of hearts. Fine structure of the terminal crest studied using light and scanning electron microscopy consisted of much thicker and more numerous fibrous sheaths of endomysium with increasing age of the patient. 36 specimens of 45 (80%) specimens studied by electron microscopy had a predominantly uniform longitudinal arrangement of myocardial fibres within the terminal crest. In contrast, in all specimens, the junctional areas of the terminal crest with the pectinate muscles and with the intercaval area had crossing and non-uniform architecture of myofibres. Conclusions: The normal anatomy of the muscle fibres and connective tissue in the junctional area of the terminal crest/pectinate muscles and terminal crest/intercaval bundle favours non-uniform anisotropic properties. PMID:12231604

Termination of persistent atrial fibrillation during pulmonary vein isolation: insight from the MAGIC-AF trial.

PubMed

Singh, Sheldon M; d'Avila, Andre; Kim, Young-Hoon; Aryana, Arash; Mangrum, J Michael; Michaud, Gregory F; Dukkipati, Srinivas R; Barrett, Conor D; Heist, E Kevin; Parides, Michael K; Thorpe, Kevin E; Reddy, Vivek Y

2017-10-01

Controversy on the optimal ablation strategy for persistent atrial fibrillation (AF) exists with limited work evaluating a strategy of pulmonary vein isolation (PVI) alone when AF terminates during PVI. Thirty-five patients had AF termination during PVI in the Modified Ablation Guided by Ibutilide Use in Chronic Atrial Fibrillation (MAGIC-AF; ClinicalTrials.gov number: NCT01014741) study. The objective of the current study is to report the 1-year outcome after PVI alone in this unique patient group. The 1-year single procedure freedom from atrial arrhythmia off anti-arrhythmic drugs was reported for the 35 patients in the MAGIC-AF study with persistent AF termination during or upon completion of PVI. Freedom from recurrent atrial arrhythmia was achieved in 60% of patients where AF terminated during PVI. Cavotricuspid isthmus flutter was common when AF terminated to a macro re-entrant flutter during PVI, and responsible for 92% of all flutter circuits with AF termination. Persistent AF termination during PVI may identify a subgroup of patients who experience a similar long-term clinical outcome with PVI ablation alone when compared with other more extensive persistent AF ablation strategies. Pulmonary vein isolation alone may be an appropriate tactic in this subgroup of persistent AF patients. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2016. For permissions please email: journals.permissions@oup.com.

Communication target object recognition for D2D connection with feature size limit

NASA Astrophysics Data System (ADS)

Ok, Jiheon; Kim, Soochang; Kim, Young-hoon; Lee, Chulhee

2015-03-01

Recently, a new concept of device-to-device (D2D) communication, which is called "point-and-link communication" has attracted great attentions due to its intuitive and simple operation. This approach enables user to communicate with target devices without any pre-identification information such as SSIDs, MAC addresses by selecting the target image displayed on the user's own device. In this paper, we present an efficient object matching algorithm that can be applied to look(point)-and-link communications for mobile services. Due to the limited channel bandwidth and low computational power of mobile terminals, the matching algorithm should satisfy low-complexity, low-memory and realtime requirements. To meet these requirements, we propose fast and robust feature extraction by considering the descriptor size and processing time. The proposed algorithm utilizes a HSV color histogram, SIFT (Scale Invariant Feature Transform) features and object aspect ratios. To reduce the descriptor size under 300 bytes, a limited number of SIFT key points were chosen as feature points and histograms were binarized while maintaining required performance. Experimental results show the robustness and the efficiency of the proposed algorithm.

No Exit: Identifying Avoidable Terminal Oncology Intensive Care Unit Hospitalizations

PubMed Central

Hantel, Andrew; Wroblewski, Kristen; Balachandran, Jay S.; Chow, Selina; DeBoer, Rebecca; Fleming, Gini F.; Hahn, Olwen M.; Kline, Justin; Liu, Hongtao; Patel, Bhakti K.; Verma, Anshu; Witt, Leah J.; Fukui, Mayumi; Kumar, Aditi; Howell, Michael D.; Polite, Blase N.

2016-01-01

Purpose: Terminal oncology intensive care unit (ICU) hospitalizations are associated with high costs and inferior quality of care. This study identifies and characterizes potentially avoidable terminal admissions of oncology patients to ICUs. Methods: This was a retrospective case series of patients cared for in an academic medical center’s ambulatory oncology practice who died in an ICU during July 1, 2012 to June 30, 2013. An oncologist, intensivist, and hospitalist reviewed each patient’s electronic health record from 3 months preceding terminal hospitalization until death. The primary outcome was the proportion of terminal ICU hospitalizations identified as potentially avoidable by two or more reviewers. Univariate and multivariate analysis were performed to identify characteristics associated with avoidable terminal ICU hospitalizations. Results: Seventy-two patients met inclusion criteria. The majority had solid tumor malignancies (71%), poor performance status (51%), and multiple encounters with the health care system. Despite high-intensity health care utilization, only 25% had documented advance directives. During a 4-day median ICU length of stay, 81% were intubated and 39% had cardiopulmonary resuscitation. Forty-seven percent of these hospitalizations were identified as potentially avoidable. Avoidable hospitalizations were associated with factors including: worse performance status before admission (median 2 v 1; P = .01), worse Charlson comorbidity score (median 8.5 v 7.0, P = .04), reason for hospitalization (P = .006), and number of prior hospitalizations (median 2 v 1; P = .05). Conclusion: Given the high frequency of avoidable terminal ICU hospitalizations, health care leaders should develop strategies to prospectively identify patients at high risk and formulate interventions to improve end-of-life care. PMID:27601514

Design of a monitor and simulation terminal (master) for space station telerobotics and telescience

NASA Technical Reports Server (NTRS)

Lopez, L.; Konkel, C.; Harmon, P.; King, S.

1989-01-01

Based on Space Station and planetary spacecraft communication time delays and bandwidth limitations, it will be necessary to develop an intelligent, general purpose ground monitor terminal capable of sophisticated data display and control of on-orbit facilities and remote spacecraft. The basic elements that make up a Monitor and Simulation Terminal (MASTER) include computer overlay video, data compression, forward simulation, mission resource optimization and high level robotic control. Hardware and software elements of a MASTER are being assembled for testbed use. Applications of Neural Networks (NNs) to some key functions of a MASTER are also discussed. These functions are overlay graphics adjustment, object correlation and kinematic-dynamic characterization of the manipulator.

ATS-1/ATS-3 dual satellite navigation study

NASA Technical Reports Server (NTRS)

Hoover, W. M.

1971-01-01

A study which illustrated the feasibility of implementing an on-board aircraft navigation system based on using the ATS-1 and ATS-3 satellites, the modified Omega Position Location Equipment (OPLE) Control Center, and a suitable aircraft terminal was conducted. The report provides: (1) a consideration of the problems of satellite navigation and an objective definition of the optimum system under the constraints of its specified components, (2) a description of the necessary modifications to the OPLE Control Center, the design of an aircraft terminal, and the design of ground reference terminals, and (3) an outline of an experiment plan and an estimate of the cost to be expected in conducting the program.

Semiparametric temporal process regression of survival-out-of-hospital.

PubMed

Zhan, Tianyu; Schaubel, Douglas E

2018-05-23

The recurrent/terminal event data structure has undergone considerable methodological development in the last 10-15 years. An example of the data structure that has arisen with increasing frequency involves the recurrent event being hospitalization and the terminal event being death. We consider the response Survival-Out-of-Hospital, defined as a temporal process (indicator function) taking the value 1 when the subject is currently alive and not hospitalized, and 0 otherwise. Survival-Out-of-Hospital is a useful alternative strategy for the analysis of hospitalization/survival in the chronic disease setting, with the response variate representing a refinement to survival time through the incorporation of an objective quality-of-life component. The semiparametric model we consider assumes multiplicative covariate effects and leaves unspecified the baseline probability of being alive-and-out-of-hospital. Using zero-mean estimating equations, the proposed regression parameter estimator can be computed without estimating the unspecified baseline probability process, although baseline probabilities can subsequently be estimated for any time point within the support of the censoring distribution. We demonstrate that the regression parameter estimator is asymptotically normal, and that the baseline probability function estimator converges to a Gaussian process. Simulation studies are performed to show that our estimating procedures have satisfactory finite sample performances. The proposed methods are applied to the Dialysis Outcomes and Practice Patterns Study (DOPPS), an international end-stage renal disease study.

Autonomous Flight Safety System - Phase III

NASA Technical Reports Server (NTRS)

2008-01-01

The Autonomous Flight Safety System (AFSS) is a joint KSC and Wallops Flight Facility project that uses tracking and attitude data from onboard Global Positioning System (GPS) and inertial measurement unit (IMU) sensors and configurable rule-based algorithms to make flight termination decisions. AFSS objectives are to increase launch capabilities by permitting launches from locations without range safety infrastructure, reduce costs by eliminating some downrange tracking and communication assets, and reduce the reaction time for flight termination decisions.

Training Corrective Maintenance Performance on Electronic Equipment with CAI Terminals: I. A Feasibility Study.

ERIC Educational Resources Information Center

Rigney, Joseph W.

A report is given of a feasibility study in which several possible relationships between student, computer terminal, and electronic equipment were considered. The simplest of these configurations was set up and examined in terms of its feasibility for teaching the performance of fault localization on a Navy transceiver. An instructional program…

Experiences of informational needs and received information following a prenatal diagnosis of congenital heart defect

PubMed Central

Bergman, Gunnar; Wadensten, Barbro; Mattsson, Elisabet

2016-01-01

Abstract Objective To explore the need for information and what information was actually received following prenatal diagnosis of a congenital heart defect, in a country where termination of pregnancy beyond 22 weeks of gestation is not easily possible because of legal constraints. Methods Twenty‐six Swedish‐speaking pregnant women (n = 14) and partners (n = 12) were consecutively recruited for semi‐structured telephone interviews following the prenatal diagnosis of a congenital heart defect. Data were analyzed using content analysis. Results Although high satisfaction with the specialist information was described, the information was considered overwhelming and complex. Objective, honest, and detailed information about multiple subjects were needed, delivered repeatedly, and supplemented by written information/illustrations. Eighteen respondents had used the Internet to search for information and identified issues involving searching difficulties, low quality, and that it was too complex, insufficient, or unspecific. Those who terminated their pregnancy criticized that there was a lack of information about termination of pregnancy, both from health professionals and online sources, resulting in unanswered questions and unpreparedness. Conclusion Individuals faced with a prenatal diagnosis of a congenital heart defect need individualized and repeated information. These needs are not all adequately met, as individuals are satisfied with the specialist consultation but left with unanswered questions regarding pregnancy termination. © 2016 The Authors. Prenatal Diagnosis published by John Wiley & Sons, Ltd. PMID:26991536

Improved transmission of electrostatic accelerator in a wide range of terminal voltages by controlling the focal strength of entrance acceleration tube

NASA Astrophysics Data System (ADS)

Lobanov, Nikolai R.; Tunningley, Thomas; Linardakis, Peter

2018-04-01

Tandem electrostatic accelerators often require the flexibility to operate at a variety of terminal voltages to accommodate various user requirements. However, the ion beam transmission will only be optimal for a limited range of terminal voltages. This paper describes the operational performance of a novel focusing system that expands the range of terminal voltages for optimal transmission. This is accomplished by controlling the gradient of the entrance of the low-energy tube, providing an additional focusing element. In this specific case it is achieved by applying up to 150 kV to the fifth electrode of the first unit of the accelerator tube. Numerical simulations and beam transmission tests have been performed to confirm the effectiveness of the lens. An analytical expression has been derived describing its focal properties. These tests demonstrate that the entrance lens control eliminates the need to short out sections of the tube for operation at low terminal voltage.

Phenylethynyl terminated imide oligomers

NASA Technical Reports Server (NTRS)

Hergenrother, Paul M. (Inventor); Bryant, Robert G. (Inventor); Jensen, Brian J. (Inventor); Havens, Stephen J. (Inventor)

1994-01-01

Four phenylethynyl amine compounds - 3 and 4-aminophenoxy-4'-phenylethynylbenzophenone, and 3 and 4-amino-4'-phenylethynylbenzophenone - were readily prepared and were used to endcap imide oligomers. Phenylethynyl-terminated amide acid oligomers and phenylethynyl-terminated imide oligomers with various molecular weights and compositions were prepared and characterized. These oligomers were cured at 300 to 400 C to provide crosslinked polyimides with excellent solvent resistance, high strength and modulus, and good high temperature properties. Adhesive panels, composites, films, and moldings from these phenylethynyl terminated imide oligomers gave excellent mechanical performance.

Phenylethynyl terminated imide oligomers

NASA Technical Reports Server (NTRS)

Hergenrother, Paul M. (Inventor); Bryant, Robert G. (Inventor); Jensen, Brian J. (Inventor); Havens, Stephen J. (Inventor)

1995-01-01

Four phenylethynyl amine compounds - 3 and 4-aminophenoxy-4'-phenylethynylbenzophenone, and 3 and 4-amino-4'-phenylethynylbenzophenone - were readily prepared and were used to endcap imide oligomers. Phenylethynyl-terminated amide acid oligomers and phenylethynyl-terminated imide oligomers with various molecular weights and compositions were prepared and characterized. These oligomers were cured at 300 to 400 C to provide crosslinked polyimides with excellent solvent resistance, high strength and modulus, and good high temperature properties. Adhesive panels, composites, films, and moldings from these phenylethynyl terminated imide oligomers gave excellent mechanical performance.

Filter line wiring designs in aircraft

NASA Astrophysics Data System (ADS)

Rowe, Richard M.

1990-10-01

The paper presents a harness design using a filter-line wire technology and appropriate termination methods to help meet high-energy radiated electromagnetic field (HERF) requirements for protection against the adverse effects of EMI on electrical and avionic systems. Filter-line interconnect harnessing systems discussed consist of high-performance wires and cables; when properly wired they suppress conducted and radiated EMI above 100 MHz. Filter-line termination devices include backshell adapters, braid splicers, and shield terminators providing 360-degree low-impedance terminations and enhancing maintainability of the system.

The right to information for the terminally ill patient.

PubMed Central

Osuna, E; Pérez-Cárceles, M D; Esteban, M A; Luna, A

1998-01-01

OBJECTIVES: To analyse the attitudes of medical personnel towards terminally ill patients and their right to be fully informed. DESIGN: Self-administered questionnaire composed of 56 closed questions. SETTING: Three general hospitals and eleven health centres in Granada (Spain). The sample comprised 168 doctors and 207 nurses. RESULTS: A high percentage of medical personnel (24.1%) do not think that informing the terminally ill would help them face their illness with greater serenity. Eighty-four per cent think the patient's own home is the best place to die: 8.9% of the subjects questioned state that the would not like to be informed of an incurable illness. CONCLUSION: In our opinion any information given should depend on the patient's personality, the stage of the illness and family circumstances. Our study confirms that a hospital is not the ideal environment for attending to the needs of the terminally ill and their families. PMID:9602997

DCS - A global satellite environmental data collection system.

NASA Technical Reports Server (NTRS)

Claire, E. J.

1973-01-01

This paper presents a summary of the results of a comparative study of satellite data collection systems which utilize remote ground data collection platforms transmitting data directly to a satellite and down to low-cost direct read-out local user terminals. The general objective of the study was to evaluate cost and technical feasibility of five medium orbiting and six geo-synchronous satellite data collection system (DCS) configurations with varying degrees of spacecraft and local user terminal (LUT) complexity. The goal of trading spacecraft and LUT complexity was to determine practical feasible systems with low-cost terminals, yet with a reasonable overall system cost the would permit the broad worldwide utilization of a highly beneficial data collection system. Results presented include data collection system analyses, satellite and local user terminal designs, and estimated costs. A summary of the types of local users and their requirements is also included.

The synthesis of monomers with pendent ethynyl group for modified high performance thermoplastics

NASA Technical Reports Server (NTRS)

Nwokogu, Godson C.; Antoine, Miquel D.; Ansong, Omari

1992-01-01

The objectives of this project were to develop synthetic schemes for the following classes of modified monomers: (1) difunctional triarylethanes with pendent acetylenic groups; and (2) tertiary aspartimides with terminal acetylene groups at the two ends. Our efforts have resulted in the successful development of high yield schemes for the syntheses of several diamino and bisphenolic analogs of difunctional triarylethanes with pendent ethynyl group. A scheme for one new tertiary aspartimide was also established. Multi-gram samples of all prepared new monomers were provided to our technical contact at NASA-LaRC and preliminary polymerization studies were encouraging. Details of the accomplished work within the last four years are described.

Genesis, Pathways, and Terminations of Intense Global Water Vapor Transport in Association with Large-Scale Climate Patterns

NASA Astrophysics Data System (ADS)

Sellars, S. L.; Kawzenuk, B.; Nguyen, P.; Ralph, F. M.; Sorooshian, S.

2017-12-01

The CONNected objECT (CONNECT) algorithm is applied to global Integrated Water Vapor Transport data from the NASA's Modern-Era Retrospective Analysis for Research and Applications - Version 2 reanalysis product for the period of 1980 to 2016. The algorithm generates life-cycle records in time and space evolving strong vapor transport events. We show five regions, located in the midlatitudes, where events typically exist (off the coast of the southeast United States, eastern China, eastern South America, off the southern tip of South Africa, and in the southeastern Pacific Ocean). Global statistics show distinct genesis and termination regions and global seasonal peak frequency during Northern Hemisphere late fall/winter and Southern Hemisphere winter. In addition, the event frequency and geographical location are shown to be modulated by the Arctic Oscillation, Pacific North American Pattern, and the quasi-biennial oscillation. Moreover, a positive linear trend in the annual number of objects is reported, increasing by 3.58 objects year-over-year.

The Anatomy of the Young Protostellar Outflow HH 211

NASA Astrophysics Data System (ADS)

Tappe, A.; Forbrich, J.; Martín, S.; Yuan, Y.; Lada, C. J.

2012-05-01

We present Spitzer Space Telescope 5-36 μm mapping observations toward the southeastern lobe of the young protostellar outflow HH 211. The southeastern terminal shock of the outflow shows a rich mid-infrared spectrum including molecular emission lines from OH, H2O, HCO+, CO2, H2, and HD. The spectrum also shows a rising infrared continuum toward 5 μm, which we interpret as unresolved emission lines from highly excited rotational levels of the CO v = 1-0 fundamental band. This interpretation is supported by a strong excess flux observed in the Spitzer/IRAC 4-5 μm channel 2 image compared to the other IRAC channels. The extremely high critical densities of the CO v = 1-0 ro-vibrational lines and a comparison to H2 and CO excitation models suggest jet densities larger than 106 cm-3 in the terminal shock. We also observed the southeastern terminal outflow shock with the Submillimeter Array and detected pure rotational emission from CO 2-1, HCO+ 3-2, and HCN 3-2. The rotationally excited CO traces the collimated outflow backbone as well as the terminal shock. HCN traces individual dense knots along the outflow and in the terminal shock, whereas HCO+ solely appears in the terminal shock. The unique combination of our mid-infrared and submillimeter observations with previously published near-infrared observations allow us to study the interaction of one of the youngest known protostellar outflows with its surrounding molecular cloud. Our results help us to understand the nature of some of the so-called green fuzzies (Extended Green Objects), and elucidate the physical conditions that cause high OH excitation and affect the chemical OH/H2O balance in protostellar outflows and young stellar objects. In an appendix to this paper, we summarize our Spitzer follow-up survey of protostellar outflow shocks to find further examples of highly excited OH occurring together with H2O and H2.

Role of Supportive Care for Terminal Stage Hepatocellular Carcinoma

PubMed Central

Kumar, Manoj; Panda, Dipanjan

2014-01-01

Patients with end stage or terminal HCC are those presenting with tumors leading to a very poor Performance Status (ECOG 3–4) or Child–Pugh C patients with tumors beyond the transplantation threshold. Among HCC patients, 15–20% present with end stage or terminal stage HCC. Their median survival is less than 3–4 months. The management of end stage or terminal HCC is only symptomatic and no definitive tumor directed treatment is indicated. Patients with end stage or terminal HCC should receive palliative support including management of pain, nutrition and psychological support. In general, they should not be considered for participating in clinical trials. This review focuses on palliative care of terminal stage HCC. PMID:25755605

Hippocampal Protein Kinase C Signaling Mediates the Short-Term Memory Impairment Induced by Delta9-Tetrahydrocannabinol.

PubMed

Busquets-Garcia, Arnau; Gomis-González, Maria; Salgado-Mendialdúa, Victòria; Galera-López, Lorena; Puighermanal, Emma; Martín-García, Elena; Maldonado, Rafael; Ozaita, Andrés

2018-04-01

Cannabis affects cognitive performance through the activation of the endocannabinoid system, and the molecular mechanisms involved in this process are poorly understood. Using the novel object-recognition memory test in mice, we found that the main psychoactive component of cannabis, delta9-tetrahydrocannabinol (THC), alters short-term object-recognition memory specifically involving protein kinase C (PKC)-dependent signaling. Indeed, the systemic or intra-hippocampal pre-treatment with the PKC inhibitors prevented the short-term, but not the long-term, memory impairment induced by THC. In contrast, systemic pre-treatment with mammalian target of rapamycin complex 1 inhibitors, known to block the amnesic-like effects of THC on long-term memory, did not modify such a short-term cognitive deficit. Immunoblot analysis revealed a transient increase in PKC signaling activity in the hippocampus after THC treatment. Thus, THC administration induced the phosphorylation of a specific Ser residue in the hydrophobic-motif at the C-terminal tail of several PKC isoforms. This significant immunoreactive band that paralleled cognitive performance did not match in size with the major PKC isoforms expressed in the hippocampus except for PKCθ. Moreover, THC transiently enhanced the phosphorylation of the postsynaptic calmodulin-binding protein neurogranin in a PKC dependent manner. These data demonstrate that THC alters short-term object-recognition memory through hippocampal PKC/neurogranin signaling.

A Low Earth Orbit satellite marine communication system demonstration

NASA Technical Reports Server (NTRS)

Elms, T. Keith; Butt, Kenneth A.; Asmus, Ken W.

1995-01-01

An application of Low Earth Orbit (LEO) satellite communications technology was investigated during a joint Canadian/American scientific expedition to the north pole in the summer of 1994. The Canadian ice breaker involved, was equipped with a store-and-forward LEO satellite terminal which was linked to a ground station in St. John's, Newfoundland, via the near-polar-orbiting satellite, HealthSat-l. The objective was to evaluate the performance of such a system while providing an alternate means of communications in the far north. The system performed well, given its inherent limitations. All 151 attempts to send data files to the ship were successful. Only two (2) of the 35 attempts to send files from the ship were unsuccessful. The files ranged in size from 0.1 to 60 Kbytes. In the high arctic, above 80 deg north, this system often provided the only practical means of data communications. This experiment demonstrated the potential of such a system for not-real-time communications with remote and/or mobile stations, and highlighted the many issues involved. This paper describes the project objectives, system configuration and experimental procedure used, related technical issues, trial results, future work, and conclusions.

Loopback Radio Frequency Translator For The Acts Mobile Terminal

NASA Technical Reports Server (NTRS)

Davis, John F.

1993-01-01

This paper summarizes the system design and performance measurements of the Loopback Translator, a satellite simulator to be used in testing the fixed and mobile terminal hardware prior to the ACTS launch.

A comparative study of n-channel low temperature poly-Si thin-film transistors with a body terminal or a lightly-doped-drain structure

NASA Astrophysics Data System (ADS)

Wu, Yanwen; Wang, Mingxiang; Wang, Huaisheng; Zhang, Dongli

2018-02-01

Hot-carrier (HC) induced degradation is a critical reliability issue of n-channel low temperature poly-Si thin-film transistors (TFTs) in TFT-based circuits. In this work, a kind of four-terminal TFT, which has an additional p+-doped lateral body terminal connecting to the floating channel, is systematically compared to conventional n-channel TFT and lightly-doped-drain (LDD) TFT. We demonstrate that the four-terminal TFT can provide similar advantages to that of the LDD TFT such as kink current suppression and DC HC degradation immunity, much superior immunity to the dynamic HC degradation, but without any tradeoffs in device performance and process complexity of the LDD TFT. It has high performance, as well as excellent reliability under both DC and AC conditions.

Terminal Performance of Lead Free Pistol Bullets in Ballistic Gelatin Using Retarding Force Analysis from High Speed Video

DTIC Science & Technology

2016-04-04

Terminal Performance of Lead-Free Pistol Bullets in Ballistic Gelatin Using Retarding Force Analysis from High Speed Video ELIJAH COURTNEY, AMY...quantified using high speed video . The temporary stretch cavities and permanent wound cavities are also characterized. Two factors tend to re- duce the...Performance of Lead-Free Pistol Bullets in Ballistic Gelatin Using Retarding Force Analysis from High Speed Video cavity. In addition, stretching can also

20 CFR 411.321 - Under what conditions will SSA terminate an agreement with an EN due to inadequate performance?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Under what conditions will SSA terminate an agreement with an EN due to inadequate performance? 411.321 Section 411.321 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Networks § 411.321 Under...

20 CFR 411.321 - Under what conditions will SSA terminate an agreement with an EN due to inadequate performance?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Under what conditions will SSA terminate an agreement with an EN due to inadequate performance? 411.321 Section 411.321 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Networks § 411.321 Under...

20 CFR 411.321 - Under what conditions will SSA terminate an agreement with an EN due to inadequate performance?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Under what conditions will SSA terminate an agreement with an EN due to inadequate performance? 411.321 Section 411.321 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Networks § 411.321 Under...

20 CFR 411.321 - Under what conditions will SSA terminate an agreement with an EN due to inadequate performance?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Under what conditions will SSA terminate an agreement with an EN due to inadequate performance? 411.321 Section 411.321 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Networks § 411.321 Under...

20 CFR 411.321 - Under what conditions will SSA terminate an agreement with an EN due to inadequate performance?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Under what conditions will SSA terminate an agreement with an EN due to inadequate performance? 411.321 Section 411.321 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Networks § 411.321 Under...

Correlation between the thermal performance and the microstructure of the material used in medium and high voltage transformer terminals

NASA Astrophysics Data System (ADS)

Salas, Y. J.; Vera-Monroy, S. P.; Mejia-Camacho, A.; Rivera, W.

2017-12-01

In Colombia, energy companies neglect the distribution that represents the main and most valuable process, presenting shortcomings in prevention and forecasting programs, using contractors who perform corrective maintenance of the components without guaranteeing the quality and performance of the materials. Within the process, the terminals determine the effective connection between the voltage line and the transformer, which have faults that are evidenced by the thermal deterioration of the material. In this work, a diagnosis of the thermal performance of these components was carried out and it was correlated with the microstructure, observing variations of the working temperature, with a thermography camera, for three types of terminals, which were classified by X-ray fluorescence in brass Z20, Z40 and Z60, and for two types of connection, copper and aluminium. The microstructure results showed that copper is the conductor that degrades the terminals faster, evidencing cracking of the material; on the other hand, the Z40 brass was the most stable with the lowest temperature variation regardless of the conductor diameter; however, in all cases the behaviour of higher temperature to lower calibre is satisfied.

The performance of cable braids and terminations to lightning induced transients

NASA Technical Reports Server (NTRS)

Crofts, David

1991-01-01

The latest specification detailing the test waveforms for indirect lightning transients as applied to aircraft wiring systems specify very high voltages and currents. Although considerable data exists for measuring cable screen leakage using such methods as surface transfer impedance and bulk cable injection, there is little data on the likely core transient level that is likely to be induced from these threats. In particular, the new Waveform 5 at very high current levels (10 kA) is reputed to cause severe cable damage. A range of representative cables were made with various screen termination techniques and screening levels. These were tested first to determine their relative screening performance and then they were subjected to lightning transient testing to all the specified waveforms. Core voltages were measured for each test. Tests were also performed on bundles with fewer wires to determine the failure criteria with Waveform 5 and these tests also include flat conductor cables. The test showed that correctly terminated cable bundles performed well in all the tests and would provide a high level of protection to the electronic systems. The use of overbraides, provided the individual screens are well terminated, appears to be unnecessary.

CLOSTRIDIUM DIFFICILE INFECTION IN ACUTE CARE HOSPITALS: SYSTEMATIC REVIEW AND BEST PRACTICES FOR PREVENTION

PubMed Central

Louh, Irene K.; Greendyke, William G.; Hermann, Emilia A.; Davidson, Karina W.; Falzon, Louise; Vawdrey, David K.; Shaffer, Jonathan A.; Calfee, David P.; Furuya, E. Yoko; Ting, Henry H.

2017-01-01

Objective Prevention of Clostridium difficile infection (CDI) in acute care hospitals is a priority for hospitals and clinicians. We performed a qualitative systematic review to update the evidence on interventions to prevent CDI published since 2009. Design We searched Ovid, MEDLINE, EMBASE, The Cochrane Library, CINAHL, ISI Web of Knowledge, and grey literature databases from January 1, 2009 to August 1, 2015. Setting We included studies performed in acute care hospitals. Patients or participants We included studies conducted on hospitalized patients that investigated the impact of specific interventions on CDI rates. Interventions We used the QI-Minimum Quality Criteria Set (QI-MQCS) to assess the quality of included studies. Interventions were grouped thematically: environmental disinfection, antimicrobial stewardship, hand hygiene, chlorhexidine bathing, probiotics, bundled approaches, and others. A meta-analysis was performed when possible. Results Of 3236 articles screened, 261 met the criteria for full-text review and 46 studies were ultimately included. The average quality rating was 82% on the QI-MQCS. The most effective interventions, resulting in a 45% to 85% reduction in CDI, included daily to twice daily disinfection of high-touch surfaces (including bed rails) and terminal cleaning of patient rooms with chlorine-based products. Bundled interventions and antimicrobial stewardship showed promise for reducing CDI rates. Chlorhexidine bathing and intensified hand hygiene practices were not effective for reducing CDI rates. Conclusions Daily and terminal cleaning of patient rooms using chlorine-based products were most effective in reducing CDI rates in hospitals. Further studies are needed to identify the components of bundled interventions that reduce CDI rates. PMID:28300019

Passenger comfort during terminal-area flight maneuvers. M.S. Thesis.

NASA Technical Reports Server (NTRS)

Schoonover, W. E., Jr.

1976-01-01

A series of flight experiments was conducted to obtain passenger subjective responses to closely controlled and repeatable flight maneuvers. In 8 test flights, reactions were obtained from 30 passenger subjects to a wide range of terminal-area maneuvers, including descents, turns, decelerations, and combinations thereof. Analysis of the passenger rating variance indicated that the objective of a repeatable flight passenger environment was achieved. Multiple linear regression models developed from the test data were used to define maneuver motion boundaries for specified degrees of passenger acceptance.

[Eye stress from work with visual screens].

PubMed

Läubli, T; Hünting, W; Grandjean, E

1980-09-01

Four groups of office tasks were studied: Data entry terminals, conversational terminals, traditional office work and typing. Eye impairments are observed in every group of office employees, but the impairments are more frequent in VDU operators. The impairments persist during leisure time. High luminance contrasts between screen and source document are associated with an increase of eye troubles. Increased oscillating luminance of characters is associated with lower visual acuity, with a higher incidence of subjective and objective symptoms of eye irritation including more frequent use of eye drops.

Economics and terminal area environmental impact of STOL transportation

NASA Technical Reports Server (NTRS)

Stewart, E. C.

1973-01-01

The impact of short takeoff and landing aircraft in meeting the needs of short haul transportation systems is analyzed. The objectives of the short haul system are evaluated on the basis of the following criteria: (1) service to the passenger, (2) economic viability, and (3) terminal area environment conditions caused by community noise, ground and air decongestion, and air pollution. Data are presented in the forms of tables, charts, and graphs. An itemization of the conclusions reached after the preliminary investigation is included.

Terminal-area STOL operating systems experiments program

NASA Technical Reports Server (NTRS)

Smith, D. W.; Watson, D.; Christensen, J. V.

1972-01-01

A system study to determine the application of short takeoff aircraft for a high speed, short haul air transportation service was conducted. The study focused on developing information which will aid in choosing system concepts, design criteria, operating procedures, landing guidance systems, air traffic control systems, and airborne avionics and flight control systems. A terminal area STOL operating system experiments program was developed. The objectives, program approach, program schedule, typical experiments, research facilities to be used, and program status are discussed.

Fostering Informed Choice: Alleviating the Trauma of Genetic Abortions.

PubMed

Asbury, Bret D

2015-01-01

Each year, thousands of pregnant women learn of fetal abnormalities through prenatal genetic analysis. This discovery--made after a woman has initially declined to exercise her right to abort an unwanted pregnancy—raises the difficult and heart-wrenching question of whether to terminate on genetic grounds. Women considering a genetic abortion rely on information and support from health care providers to assist them in making their choice. Though intended to be objective and nondirective, the support women receive frequently provides them within complete and incomprehensible information having the effect of encouraging them to abort genetically anomalous fetuses. As a result, genetic terminations--which cause severe and long-standing psychological impacts such as pathological grief, depression and post-traumatic stress—are often the result of something other than a fully informed choice.Congress and eleven states have recognized the importance of better informing choice by passing legislation aimed at providing clearer and more balanced information to expectant mothers learning of fetal genetic abnormalities. But existing legislative remedies do not adequately address this problem, and this inadequacy will become more pronounced in future years as increases in access to prenatal genetic analysis further stretch the capabilities of the available support services.This Article describes the unique characteristics of terminations for a fetal abnormality, their troubling and persistent psychological impacts,and the reasons why they will become more common in future years. It then offers proposals for how to reconfigure the prenatal genetic counseling landscape in order to reduce the incidence of genetic terminations based on incomplete or misleading information, thereby alleviating their distinct psychological costs. Its overall objective is to ensure that women learning of prenatal genetic abnormalities have access to complete and comprehensible information prior to making their decision and adequate support whether or not they choose to terminate.

Oral health conditions affect functional and social activities of terminally-ill cancer patients

PubMed Central

Fischer, D.J.; Epstein, J.B.; Yao, Y.; Wilkie, D.J.

2013-01-01

Purpose Oral conditions are established complications in terminally-ill cancer patients. Yet despite significant morbidity, the characteristics and impact of oral conditions in these patients are poorly documented. The study objective was to characterize oral conditions in terminally-ill cancer patients to determine the presence, severity, and the functional and social impact of these oral conditions. Methods This was an observational clinical study including terminally-ill cancer patients (2.5–3 week life expectancy). Data were obtained via the Oral Problems Scale (OPS) that measures the presence of subjective xerostomia, orofacial pain, taste change, and the functional/social impact of oral conditions and a demographic questionnaire. A standardized oral examination was used to assess objective salivary hypofunction, fungal infection, mucosal erythema, and ulceration. Regression analysis and t test investigated the associations between measures. Results Of 104 participants, most were ≥50 years of age, female, and high-school educated; 45% were African American, 43% Caucasian, and 37% married. Oral conditions frequencies were: salivary hypofunction (98%), mucosal erythema (50%), ulceration (20%), fungal infection (36%), and other oral problems (46%). Xerostomia, taste change, and orofacial pain all had significant functional impact; p<.001, p=.042 and p<.001, respectively. Orofacial pain also had a significant social impact (p<.001). Patients with oral ulcerations had significantly more orofacial pain with a social impact than patients without ulcers (p=.003). Erythema was significantly associated with fungal infection and with mucosal ulceration (p<.001). Conclusions Oral conditions significantly affect functional and social activities in terminally-ill cancer patients. Identification and management of oral conditions in these patients should therefore be an important clinical consideration. PMID:24232310

High-performance fractional order terminal sliding mode control strategy for DC-DC Buck converter

PubMed Central

Xu, Dan; Zhou, Huan; Bai, Anning; Lu, Wei

2017-01-01

This paper presents an adaption of the fractional order terminal sliding mode control (AFTSMC) strategy for DC-DC Buck converter. The following strategy aims to design a novel nonlinear sliding surface function, with a double closed-loop structure of voltage and current. This strategy is a fusion of two characteristics: terminal sliding mode control (TSMC) and fractional order calculation (FOC). In addition, the influence of “the controller parameters” on the “performance of double closed-loop system” is investigated. It is observed that the value of terminal power has to be chosen to make a compromise between start-up and transient response of the converter. Therefore the AFTSMC strategy chooses the value of the terminal power adaptively, and this strategy can lead to the appropriate number of fractional order as well. Furthermore, through the fractional order analysis, the system can reach the sliding mode surface in a finite time. And the theoretical considerations are verified by numerical simulation. The performance of the AFTSMC and TSMC strategies is tested by computer simulations. And the comparison simulation results show that the AFTSMC exhibits a considerable improvement in terms of a faster output voltage response during load changes. Moreover, AFTSMC obtains a faster dynamical response, smaller steady-state error rate and lower overshoot. PMID:29084255

High-performance fractional order terminal sliding mode control strategy for DC-DC Buck converter.

PubMed

Wang, Jianlin; Xu, Dan; Zhou, Huan; Bai, Anning; Lu, Wei

2017-01-01

This paper presents an adaption of the fractional order terminal sliding mode control (AFTSMC) strategy for DC-DC Buck converter. The following strategy aims to design a novel nonlinear sliding surface function, with a double closed-loop structure of voltage and current. This strategy is a fusion of two characteristics: terminal sliding mode control (TSMC) and fractional order calculation (FOC). In addition, the influence of "the controller parameters" on the "performance of double closed-loop system" is investigated. It is observed that the value of terminal power has to be chosen to make a compromise between start-up and transient response of the converter. Therefore the AFTSMC strategy chooses the value of the terminal power adaptively, and this strategy can lead to the appropriate number of fractional order as well. Furthermore, through the fractional order analysis, the system can reach the sliding mode surface in a finite time. And the theoretical considerations are verified by numerical simulation. The performance of the AFTSMC and TSMC strategies is tested by computer simulations. And the comparison simulation results show that the AFTSMC exhibits a considerable improvement in terms of a faster output voltage response during load changes. Moreover, AFTSMC obtains a faster dynamical response, smaller steady-state error rate and lower overshoot.

Attitudes of oncologists toward euthanasia in Turkey.

PubMed

Mayda, Atilla Senih; Ozkara, Erdem; Corapçioğlu, Funda

2005-09-01

There have been intensive debates about euthanasia and attempts to change laws on euthanasia in all countries. What doctors and particularly oncologists think about euthanasia must be taken into consideration, as their voices are crucial in this dialogue. The aim of this study was to find out how Turkish doctors approach euthanasia in the context of cancer. A questionnaire was used to collect data from 85 oncologists out of a total 800 in active oncology practice. Of the oncologists surveyed, 43.8% did not object to euthanasia. Some 33.7% had been asked to perform euthanasia and 41.5% believed that euthanasia was performed secretly although it is against the law in Turkey. Forty-two doctors (50.6%) noted that they had withdrawn treatment in patients. Doctors who encounter terminally ill patients with cancer should update their knowledge about patients' rights and euthanasia. Doctors, who are often asked to perform euthanasia, especially in the cancer setting, can help to illuminate the debates about euthanasia.

Pediatric Critical Care Transport as a Conduit to Terminal Extubation at Home: A Case Series.

PubMed

Noje, Corina; Bernier, Meghan L; Costabile, Philomena M; Klein, Bruce L; Kudchadkar, Sapna R

2017-01-01

To present our single-center's experience with three palliative critical care transports home from the PICU for terminal extubation. We performed a retrospective chart review of patients transported between January 1, 2012, and December 31, 2014. All cases were identified from our institutional pediatric transport database. Patients were terminally ill children unable to separate from mechanical ventilation in the PICU, who were transported home for terminal extubation and end-of-life care according to their families' wishes. Patients underwent palliative care transport home for terminal extubation. The rate of palliative care transports home for terminal extubation during the study period was 2.6 per 100 deaths. The patients were 7 months, 6 years, and 18 years old and had complex chronic conditions. The transfer process was protocolized. The families were approached by the PICU staff during multidisciplinary goals-of-care meetings. Parental expectations were clarified, and home hospice care was arranged pretransfer. All transports were performed by our pediatric critical care transport team, and all terminal extubations were performed by physicians. All patients had unstable medical conditions and urgent needs for transport to comply with the families' wishes for withdrawal of life support and death at home. As such, all three cases presented similar logistic challenges, including establishing do-not-resuscitate status pretransport, having limited time to organize the transport, and coordinating home palliative care services with available community resources. Although a relatively infrequent practice in pediatric critical care, transport home for terminal extubation represents a feasible alternative for families seeking out-of-hospital end-of-life care for their critically ill technology-dependent children. Our single-center experience supports the need for development of formal programs for end-of-life critical care transports to include patient screening tools, palliative care home discharge algorithms, transport protocols, and resource utilization and cost analyses.

A 15.3 GHz satellite-to-ground diversity propagation experiment using a terminal separation of 4 kilometers

NASA Technical Reports Server (NTRS)

Grimm, K. R.; Hodge, D. B.

1971-01-01

The performance of a path diversity satellite-to-ground millimeter wave link with two ground terminals separated by 4 km is discussed. At this separation distance the duration of fades below 6 dB was decreased by at least a factor of 10 when using path diversity and the cumulative crosscorrelation between the attenuations observed at the two terminals during rain events was approximately 0.45. Narrow beam radiometers directed along the propagation paths were also utilized to relate the path radiometric temperature to the path attenuation. An analysis of downlink propagation data for generating diversity link performance statistics is included.

Implementation of LSCMA adaptive array terminal for mobile satellite communications

NASA Astrophysics Data System (ADS)

Zhou, Shun; Wang, Huali; Xu, Zhijun

2007-11-01

This paper considers the application of adaptive array antenna based on the least squares constant modulus algorithm (LSCMA) for interference rejection in mobile SATCOM terminals. A two-element adaptive array scheme is implemented with a combination of ADI TS201S DSP chips and Altera Stratix II FPGA device, which makes a cooperating computation for adaptive beamforming. Its interference suppressing performance is verified via Matlab simulations. Digital hardware system is implemented to execute the operations of LSCMA beamforming algorithm that is represented by an algorithm flowchart. The result of simulations and test indicate that this scheme can improve the anti-jamming performance of terminals.

Control of nonlinear systems using terminal sliding modes

NASA Technical Reports Server (NTRS)

Venkataraman, S. T.; Gulati, S.

1992-01-01

The development of an approach to control synthesis for robust robot operations in unstructured environments is discussed. To enhance control performance with full model information, the authors introduce the notion of terminal convergence and develop control laws based on a class of sliding modes, denoted as terminal sliders. They demonstrate that terminal sliders provide robustness to parametric uncertainty without having to resort to high-frequency control switching, as in the case of conventional sliders. It is shown that the proposed method leads to greater guaranteed precision in all control cases discussed.

Guidebook for Developing Criterion-Referenced Tests

DTIC Science & Technology

1975-08-01

struction (each student learning at his own pace ), and then tested when he felt prepared to take the test. Note that an NRT is des 4 grea to spread people out...be able to build a CRT. A properly constructed CRT will allow you to classify the people who take it into two groups: , Masters--those who you are...Instructioial Objectives * Instructional Goals e Learning Objectives 9 Terminal Training Objectives This level describes work activities which can stand by

Voltammetric and impedance behaviours of surface-treated nano-crystalline diamond film electrodes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, F. B.; Jing, B.; Cui, Y.

2015-04-15

The electrochemical performances of hydrogen- and oxygen-terminated nano-crystalline diamond film electrodes were investigated by cyclic voltammetry and AC impedance spectroscopy. In addition, the surface morphologies, phase structures, and chemical states of the two diamond films were analysed by scanning probe microscopy, Raman spectroscopy, and X-ray photoelectron spectroscopy, respectively. The results indicated that the potential window is narrower for the hydrogen-terminated nano-crystalline diamond film than for the oxygen-terminated one. The diamond film resistance and capacitance of oxygen-terminated diamond film are much larger than those of the hydrogen-terminated diamond film, and the polarization resistances and double-layer capacitance corresponding to oxygen-terminated diamond filmmore » are both one order of magnitude larger than those corresponding to the hydrogen-terminated diamond film. The electrochemical behaviours of the two diamond film electrodes are discussed.« less

Transportable satellite voice terminals in Canada's north: Benefits from the users' perspectives

NASA Astrophysics Data System (ADS)

Sivertz, Christopher B.

Infosat Telecommunications has developed a series of Ku-band transportable terminals for toll-quality telecommunications applications. These terminals are designed to provide reliable telephone, Group III facsimile, and computer data to users needing communications on short notice. The terminals are capable of providing full duplex service interconnecting into the public switched network or operating as an off-premise extension of an office private branch exchange. The terminals use a 1.8 m antenna and can be deployed from the back of a pick-up truck, single axle trailer or surface-mounted metal base. They operate reliable in extreme conditions and are very satellite efficient. This paper describes the features and performance of these terminals. Highlights of a number of remote installations are also discussed.

Flight performance of the TCV B-737 airplane at Jorge Newberry Airport, Buenos Aires, Argentina using TRSB/MLS guidance

NASA Technical Reports Server (NTRS)

White, W. F.; Clark, L.

1980-01-01

The flight performance of the Terminal Configured Vehicle airplane is summarized. Demonstration automatic approaches and landings utilizing time reference scanning beam microwave landing system (TRSB/MLS) guidance are presented. The TRSB/MLS was shown to provide the terminal area guidance necessary for flying curved automatic approaches with final legs as short as 2 km.

Flight demonstration of flight termination system and solid rocket motor ignition using semiconductor laser initiated ordnance

NASA Astrophysics Data System (ADS)

Schulze, Norman R.; Maxfield, B.; Boucher, C.

1995-01-01

Solid State Laser Initiated Ordnance (LIO) offers new technology having potential for enhanced safety, reduced costs, and improved operational efficiency. Concerns over the absence of programmatic applications of the technology, which has prevented acceptance by flight programs, should be abated since LIO has now been operationally implemented by the Laser Initiated Ordnance Sounding Rocket Demonstration (LOSRD) Program. The first launch of solid state laser diode LIO at the NASA Wallops Flight Facility (WFF) occurred on March 15, 1995 with all mission objectives accomplished. This project, Phase 3 of a series of three NASA Headquarters LIO demonstration initiatives, accomplished its objective by the flight of a dedicated, all-LIO sounding rocket mission using a two-stage Nike-Orion launch vehicle. LIO flight hardware, made by The Ensign-Bickford Company under NASA's first Cooperative Agreement with Profit Making Organizations, safely initiated three demanding pyrotechnic sequence events, namely, solid rocket motor ignition from the ground and in flight, and flight termination, i.e., as a Flight Termination System (FTS). A flight LIO system was designed, built, tested, and flown to support the objectives of quickly and inexpensively putting LIO through ground and flight operational paces. The hardware was fully qualified for this mission, including component testing as well as a full-scale system test. The launch accomplished all mission objectives in less than 11 months from proposal receipt. This paper concentrates on accomplishments of the ordnance aspects of the program and on the program's implementation and results. While this program does not generically qualify LIO for all applications, it demonstrated the safety, technical, and operational feasibility of those two most demanding applications, using an all solid state safe and arm system in critical flight applications.

Wake Vortex Field Measurement Program at Memphis, Tennessee: Data Guide

NASA Technical Reports Server (NTRS)

Campbell, S. D.; Dasey, T. J.; Freehart, R. E.; Heinrichs, R. M.; Mathews, M. P.; Perras, G. H.; Rowe, G. S.

1997-01-01

Eliminating or reducing current restrictions in the air traffic control system due to wake vortex considerations would yield increased capacity, decreased delays, and cost savings. Current wake vortex separation standards are widely viewed as very conservative under most conditions. However, scientific uncertainty about wake vortex behavior under different atmospheric conditions remains a barrier to development of an adaptive vortex spacing system. The objective of the wake vortex field measurement efforts during December, 1994 and August, 1995 at Memphis, TN were to record wake vortex behavior for varying atmospheric conditions and types of aircraft. This effort is part of a larger effort by the NASA Langley Research Center to develop an Aircraft Vortex Spacing System (AVOSS) as an element of the Terminal Area Productivity (TAP) program. The TAP program is being performed in concert with the FAA Terminal Air Traffic Control Automation (TATCA) program and ATC Automation. Wake vortex behavior was observed using a mobile continuous-wave (CW) coherent laser Doppler radar (lidar) developed at Lincoln Laboratory. This lidar features a number of improvements over previous systems, including the first-ever demonstration of an automatic wake vortex detection and tracking algorithm.

Comparative Study of Optical and Radio-Frequency Communication Systems for a Deep-Space Mission

NASA Technical Reports Server (NTRS)

Hemmati, H.; Wilson, K.; Sue, M. K.; Harcke, L. J.; Wilhelm, M.; Chen, C.-C.; Lesh, J.; Feria, Y.; Rascoe, D.; Lansing, F.

1997-01-01

We have performed a study on telecommunication systems for a hypothetical mission to Mars. The objective of the study was to evaluate and compare the benefits that microwave-X-band (8.4 GHz) and Ka-band (32 GHz) - and optical communications technologies a afford to future missions. The telecommunication systems were required to return data after launch and in orbit at 2.7 AU with daily data volumes of 0.1, 1.0, or 10.0 Gbits (Gb). Spacecraft terminals capable of delivering each of the three data volumes were proposed and characterized in terms of mass, power consumption, size, and cost. The estimated parameters for X-band, Ka-band, and optical frequencies are compared and presented here. For all cases, the optical light terminal exhibits about 60 percent of the mass of the corresponding radio frequency (RF) subsystem. Power consumption is comparable for all three technologies at a 0.1 Gb/day data volume, but the power required at either Ka-band or optical is less than half of the X-band requirement at 10 Gb/day. These benefits can be obtained only with a suitable investment in reception facilities for Ka-band or optical frequencies.

Sex differences present in auditory looming perception, absent in auditory recession

NASA Astrophysics Data System (ADS)

Neuhoff, John G.; Seifritz, Erich

2005-04-01

When predicting the arrival time of an approaching sound source, listeners typically exhibit an anticipatory bias that affords a margin of safety in dealing with looming objects. The looming bias has been demonstrated behaviorally in the laboratory and in the field (Neuhoff 1998, 2001), neurally in fMRI studies (Seifritz et al., 2002), and comparatively in non-human primates (Ghazanfar, Neuhoff, and Logothetis, 2002). In the current work, male and female listeners were presented with three-dimensional looming sound sources and asked to press a button when the source was at the point of closest approach. Females exhibited a significantly greater anticipatory bias than males. Next, listeners were presented with sounds that either approached or receded and then stopped at three different terminal distances. Consistent with the time-to-arrival judgments, female terminal distance judgments for looming sources were significantly closer than male judgments. However, there was no difference between male and female terminal distance judgments for receding sounds. Taken together with the converging behavioral, neural, and comparative evidence, the current results illustrate the environmental salience of looming sounds and suggest that the anticipatory bias for auditory looming may have been shaped by evolution to provide a selective advantage in dealing with looming objects.

Design Considerations for a New Terminal Area Arrival Scheduler

NASA Technical Reports Server (NTRS)

Thipphavong, Jane; Mulfinger, Daniel

2010-01-01

Design of a terminal area arrival scheduler depends on the interrelationship between throughput, delay and controller intervention. The main contribution of this paper is an analysis of the above interdependence for several stochastic behaviors of expected system performance distributions in the aircraft s time of arrival at the meter fix and runway. Results of this analysis serve to guide the scheduler design choices for key control variables. Two types of variables are analyzed, separation buffers and terminal delay margins. The choice for these decision variables was tested using sensitivity analysis. Analysis suggests that it is best to set the separation buffer at the meter fix to its minimum and adjust the runway buffer to attain the desired system performance. Delay margin was found to have the least effect. These results help characterize the variables most influential in the scheduling operations of terminal area arrivals.

Mechanisms and treatment of cancer cachexia.

PubMed

Argilés, J M; López-Soriano, F J; Busquets, S

2013-12-01

According to a recent consensus, cachexia is a complex metabolic syndrome associated with underlying illness and characterised by loss of muscle with or without loss of fat mass. The prominent clinical feature of cachexia is weight loss. Cachexia occurs in the majority of terminal cancer patients and it is responsible for the deaths of 22% of cancer patients. Although body weight is, indeed, an important factor to be taken into consideration in any cachexia treatment, body composition, physical performance and quality of life should be monitored. From the results presented here, one can speculate that a single therapy may not be completely successful in the treatment of cachexia. From this point of view, treatments involving different combinations are more likely to be successful. The objectives of any therapeutical combination are two: an anticatabolic aim directed towards both fat and muscle catabolism and an anabolic objective leading to the synthesis of macromolecules such as contractile proteins. Copyright © 2012 Elsevier B.V. All rights reserved.

A computational NMR study on zigzag aluminum nitride nanotubes

NASA Astrophysics Data System (ADS)

Bodaghi, Ali; Mirzaei, Mahmoud; Seif, Ahmad; Giahi, Masoud

2008-12-01

A computational nuclear magnetic resonance (NMR) study is performed to investigate the electronic structure properties of the single-walled zigzag aluminum nitride nanotubes (AlNNTs). The chemical-shielding (CS) tensors are calculated at the sites of Al-27 and N-15 nuclei in three structural forms of AlNNT including H-saturated, Al-terminated, and N-terminated ones. The structural forms are firstly optimized and then the calculated CS tensors in the optimized structures are converted to chemical-shielding isotropic (CSI) and chemical-shielding anisotropic (CSA) parameters. The calculated parameters reveal that various Al-27 and N-15 nuclei are divided into some layers with equivalent electrostatic properties; furthermore, Al and N can act as Lewis base and acid, respectively. In the Al-terminated and N-terminated forms of AlNNT, in which one mouth of the nanotube is terminated by aluminum and nitrogen nuclei, respectively, just the CS tensors of the nearest nuclei to the mouth of the nanotube are significantly changed due to removal of saturating hydrogen atoms. Density functional theory (DFT) calculations are performed using GAUSSIAN 98 package of program.

Reference system for scanning probe tip fingerprinting

NASA Astrophysics Data System (ADS)

Turansky, Robert; Bamidele, Joseph; Sugawara, Yasuhiro; Kantorovitch, Lev; Stich, Ivan

2012-02-01

Knowledge of the chemical structure of the tip asperity in Non-Contact Atomic Force Microscopy (NC-AFM) is crucial as controlled manipulation of atoms and/or molecules on surfaces can only be performed if this information is available. However, a simple and robust protocol for ensuring a specific tip termination has not yet been developed. We propose a procedure for chemical tip finger printing and an example of a reference system, the oxygen-terminated Cu(110) surface, that enables one to ensure a specific tip termination with Si, Cu, or O atoms. To follow this up and unambiguously determine tip types, we performed a theoretical DFT study of the line scans with the tip models in question and found that the tip characterization made based on experimental results (Cu/O-terminated tip imaging Cu/O atoms) is in fact incorrect and the opposite is true (Cu/O-terminated tip imaging O/Cu atoms). This protocol allows the tip asperity's chemical structure to be verified and established both before as well as at any stage of the manipulation experiment when numerous tip changes may take place.

Objective Speech Quality Assessment Based on Payload Discrimination of Lost Packets for Cellular Phones in NGN Environment

NASA Astrophysics Data System (ADS)

Uemura, Satoshi; Fukumoto, Norihiro; Yamada, Hideaki; Nakamura, Hajime

A feature of services provided in a Next Generation Network (NGN) is that the end-to-end quality is guaranteed. This is quite a challenging issue, given the considerable fluctuation in network conditions within a Fixed Mobile Convergence (FMC) network. Therefore, a novel approach, whereby a network node and a mobile terminal such as a cellular phone cooperate with each other to control service quality is essential. In order to achieve such cooperation, the mobile terminal needs to become more intelligent so it can estimate the service quality, including the user's perceptual quality, and notify the measurement result to the network node. Subsequently, the network node implements some kind of service control function, such as a resource and admission control function, based on the notification from the mobile terminal. In this paper, the role of the mobile terminal in such collaborative system is focused on. As a part of a QoS/QoE measurement system, we describe an objective speech quality assessment with payload discrimination of lost packets to measure the user's perceptual quality of VoIP. The proposed assessment is so simple that it can be implemented on a cellular phone. We therefore did this as part of the QoS/QoE measurement system. By using the implemented system, we can measure the user's perceptual quality of VoIP as well as the network QoS metrics, in terms of criteria such as packet loss rate, jitter and burstiness in real time.

Simulation for assessment of bulk cargo berths number

NASA Astrophysics Data System (ADS)

Kuznetsov, A. L.; Kirichenko, A. V.; Slitsan, A. E.

2017-10-01

The world trade volumes of mineral resources have been growing constantly for decades, notwithstanding any economical crises. At the same time, the proximity of the bulk materials as products to the starting point of the integrated value added or logistic supply chain makes their unit price relatively low. This fact automatically causes a strong economic sensitivity of the supply chain to the level of operational expenses in every link. The core of the integrated logistic supply chain is its maritime segment, with the fleet and terminals (i.e. the cargo transportation system) serving as the base platform for it. In its turn, the terminal berths play a role of the interface between the fleet and the land-transportation sub-system. Current development of the maritime transportation technologies, ships and terminal specialization, vessel size growth, rationalization of route patterns, regionalization of trade etc., has made conventional calculation methods inadequate. The solution of the problem is in using object oriented simulation. At the same time, this approch usually assumes only ad hoc models. Thus, it does not provide the generality of its conventional analytical predecessors. The time and labor consumpting procedure of simulation results in a very narrow application domain of the model. This article describes a new simulation instrument, combining the generality of the analytical technoques with the efficiency of the object-oriented simulation. The approach implemented as a software module, which validity and adequacy are proved. The software was tested on several sea terminal design projects and confirmed its efficiency.

Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells.

PubMed

Markiewicz, Margaret; Nakerakanti, Sashidhar S; Kapanadze, Bagrat; Ghatnekar, Angela; Trojanowska, Maria

2011-01-01

The primary objective of this study was to examine the potential interaction between S1P, a pleiotropic lipid mediator, and CTGF/CCN2, a secreted multimodular protein, in the process of endothelial cell migration. The secondary objective was to determine whether C- and N-terminal domains of CTGF/CCN2 have a specific function in cell migration. Migration of HDMECs was examined in monolayer wound healing "scratch" assay, whereas capillary-like tube formation was examined in three-dimensional collagen co-culture assays. We observed that S1P stimulates migration of HDMECs concomitant with upregulation of CTGF/CCN2 expression. Furthermore, the blockade of endogenous CTGF/CCN2 via siRNA abrogated S1P-induced HDMEC migration and capillary-like tube formation. Full-length CTGF induced cell migration and capillary-like tube formation with a potency similar to that of S1P, while C-terminal domain of CTGF was slightly less effective. However, N-terminal domain had only a residual activity in inducing capillary-like tube formation. This study revealed that CTGF/CCN2 is required for the S1P-induced endothelial cell migration, which suggests that CTGF/CCN2 may be an important mediator of S1P-induced physiological and pathological angiogenesis. Moreover, this study shows that the pro-migratory activity of CTGF/CCN2 is located in the C-terminal domain. © 2010 John Wiley & Sons Ltd.

30 CFR 291.101 - What definitions apply to this part?

Code of Federal Regulations, 2010 CFR

2010-07-01

... equipment, device, apparatus, or other object attached to a horizontal component or riser. Examples include...), pipeline end terminals (PLETs), anode sleds, other sleds, and jumpers (other than jumpers connecting subsea...

Output power distributions of terminals in a 3G mobile communication network.

PubMed

Persson, Tomas; Törnevik, Christer; Larsson, Lars-Eric; Lovén, Jan

2012-05-01

The objective of this study was to examine the distribution of the output power of mobile phones and other terminals connected to a 3G network in Sweden. It is well known that 3G terminals can operate with very low output power, particularly for voice calls. Measurements of terminal output power were conducted in the Swedish TeliaSonera 3G network in November 2008 by recording network statistics. In the analysis, discrimination was made between rural, suburban, urban, and dedicated indoor networks. In addition, information about terminal output power was possible to collect separately for voice and data traffic. Information from six different Radio Network Controllers (RNCs) was collected during at least 1 week. In total, more than 800000 h of voice calls were collected and in addition to that a substantial amount of data traffic. The average terminal output power for 3G voice calls was below 1 mW for any environment including rural, urban, and dedicated indoor networks. This is <1% of the maximum available output power. For data applications the average output power was about 6-8 dB higher than for voice calls. For rural areas the output power was about 2 dB higher, on average, than in urban areas. Copyright © 2011 Wiley Periodicals, Inc.

The link evaluation terminal for the advanced communications technology satellite experiments program

NASA Technical Reports Server (NTRS)

May, Brian D.

1992-01-01

The experimental NASA satellite, Advanced Communications Technology Satellite (ACTS), introduces new technology for high throughput 30 to 20 GHz satellite services. Contained in a single communication payload is both a regenerative TDMA system and multiple 800 MHz 'bent pipe' channels routed to spot beams by a switch matrix. While only one mode of operation is typical during any experiment, both modes can operate simultaneously with reduced capability due to sharing of the transponder. NASA-Lewis instituted a ground terminal development program in anticipation of the satellite launch to verify the performance of the switch matrix mode of operations. Specific functions are built into the ground terminal to evaluate rain fade compensation with uplink power control and to monitor satellite transponder performance with bit error rate measurements. These functions were the genesis of the ground terminal's name, Link Evaluation Terminal, often referred to as LET. Connectors are included in LET that allow independent experimenters to run unique modulation or network experiments through ACTS using only the RF transmit and receive portions of LET. Test data indicate that LET will be able to verify important parts of ACTS technology and provide independent experimenters with a useful ground terminal. Lab measurements of major subsystems integrated into LET are presented. Bit error rate is measured with LET in an internal loopback mode.

Truck Terminal and Warehouse Survey Results

DOT National Transportation Integrated Search

1996-03-01

The survey of truck terminals and warehouses resulted in locating the highway bottlenecks for truck movements which are more localized in nature than the previous air, marine, and rail surveys performed by the NYMTC Central Staff. However, all of the...

46 CFR 232.5 - Income Statement Accounts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... as terminal operations, cargo equipment, fleet operations, cargo pooling agreements, container... revenue from pooling agreements, terminal services provided to others, and cargo handling services performed for others; cargo equipment rentals, and repairs to cargo equipment belonging to others; agency...

46 CFR 232.5 - Income Statement Accounts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... as terminal operations, cargo equipment, fleet operations, cargo pooling agreements, container... revenue from pooling agreements, terminal services provided to others, and cargo handling services performed for others; cargo equipment rentals, and repairs to cargo equipment belonging to others; agency...

46 CFR 232.5 - Income Statement Accounts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... as terminal operations, cargo equipment, fleet operations, cargo pooling agreements, container... revenue from pooling agreements, terminal services provided to others, and cargo handling services performed for others; cargo equipment rentals, and repairs to cargo equipment belonging to others; agency...

46 CFR 232.5 - Income Statement Accounts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... as terminal operations, cargo equipment, fleet operations, cargo pooling agreements, container... revenue from pooling agreements, terminal services provided to others, and cargo handling services performed for others; cargo equipment rentals, and repairs to cargo equipment belonging to others; agency...

Flight performance of the TCV B-737 airplane at Kennedy Airport using TRSB/MLS guidance

NASA Technical Reports Server (NTRS)

White, W. F.; Clark, L. V.

1979-01-01

The terminal configured vehicle (TCV) B 737 was flown in demonstration of the time reference scanning beam/microwave landing system (TRSB/MLS). The flight performance of the TCV airplane during the demonstration automatic approaches and landings while utilizing TRSB/MLS guidance is reported. The TRSB/MLS is shown to provide the terminal area guidance necessary for flying curved automatic approaches with short finals.

Performance evaluation and comparison of three-terminal energy selective electron devices with different connective ways and filter configurations

NASA Astrophysics Data System (ADS)

Peng, Wanli; Zhang, Yanchao; Yang, Zhimin; Chen, Jincan

2018-02-01

Three-terminal energy selective electron (ESE) devices consisting of three electronic reservoirs connected by two energy filters and an electronic conductor with negligible resistance may work as ESE refrigerators and amplifiers. They have three possible connective ways for the electronic conductor and six electronic transmission forms. The configuration of energy filters may be described by the different transmission functions such as the rectangular and Lorentz transmission functions. The ESE devices with three connective ways can be, respectively, regarded as three equivalent hybrid systems composed of an ESE heat engine and an ESE refrigerator/heat pump. With the help of the theory of the ESE devices operated between two electronic reservoirs, the coefficients of performance and cooling rates (heat-pumping rates) of hybrid systems are directly derived. The general performance characteristics of hybrid systems are revealed. The optimal regions of these devices are determined. The performances of the devices with three connective ways of the electronic conductor and two configurations of energy filters are compared in detail. The advantages and disadvantages of each of three-terminal ESE devices are expounded. The results obtained here may provide some guidance for the optimal design and operation of three-terminal ESE devices.

Optical fiber systems for the BigBOSS instrument

NASA Astrophysics Data System (ADS)

Edelstein, Jerry; Poppett, Claire; Sirk, Martin; Besuner, Robert; Lafever, Robin; Allington-Smith, Jeremy R.; Murray, Graham J.

2012-09-01

We describe the fiber optics systems for use in BigBOSS, a proposed massively parallel multi-object spectrograph for the Kitt Peak Mayall 4-m telescope that will measure baryon acoustic oscillations to explore dark energy. BigBOSS will include 5,000 optical fibers each precisely actuator-positioned to collect an astronomical target’s flux at the telescope prime-focus. The fibers are to be routed 40m through the telescope facility to feed ten visible-band imaging spectrographs. We report on our fiber component development and performance measurement program. Results include the numerical modeling of focal ratio degradation (FRD), observations of actual fibers’ collimated and converging beam FRD, and observations of FRD from different types of fiber terminations, mechanical connectors, and fusion-splice connections.

Electric terminal performance and characterization of solid oxide fuel cells and systems

NASA Astrophysics Data System (ADS)

Lindahl, Peter Allan

Solid Oxide Fuel Cells (SOFCs) are electrochemical devices which can effect efficient, clean, and quiet conversion of chemical to electrical energy. In contrast to conventional electricity generation systems which feature multiple discrete energy conversion processes, SOFCs are direct energy conversion devices. That is, they feature a fully integrated chemical to electrical energy conversion process where the electric load demanded of the cell intrinsically drives the electrochemical reactions and associated processes internal to the cell. As a result, the cell's electric terminals provide a path for interaction between load side electric demand and the conversion side processes. The implication of this is twofold. First, the magnitude and dynamic characteristics of the electric load demanded of the cell can directly impact the long-term efficacy of the cell's chemical to electrical energy conversion. Second, the electric terminal response to dynamic loads can be exploited for monitoring the cell's conversion side processes and used in diagnostic analysis and degradation-mitigating control schemes. This dissertation presents a multi-tier investigation into this electric terminal based performance characterization of SOFCs through the development of novel test systems, analysis techniques and control schemes. First, a reference-based simulation system is introduced. This system scales up the electric terminal performance of a prototype SOFC system, e.g. a single fuel cell, to that of a full power-level stack. This allows realistic stack/load interaction studies while maintaining explicit ability for post-test analysis of the prototype system. Next, a time-domain least squares fitting method for electrochemical impedance spectroscopy (EIS) is developed for reduced-time monitoring of the electrochemical and physicochemical mechanics of the fuel cell through its electric terminals. The utility of the reference-based simulator and the EIS technique are demonstrated through their combined use in the performance testing of a hybrid-source power management (HSPM) system designed to allow in-situ EIS monitoring of a stack under dynamic loading conditions. The results from the latter study suggest that an HSPM controller allows an opportunity for in-situ electric terminal monitoring and control-based mitigation of SOFC degradation. As such, an exploration of control-based SOFC degradation mitigation is presented and ideas for further work are suggested.

Unmarried women's decisions on pregnancy termination: Qualitative interviews in Colombo, Sri Lanka.

PubMed

Olsson, Pia; Wijewardena, Kumudu

2010-11-01

In Sri Lanka pregnancy termination is very restricted by law and social norms. Premarital sex, and pregnancies are not generally accepted and unmarried pregnant women are vulnerable in their decision-making on pregnancy termination. The objective of this study was to describe the circumstances of becoming pregnant and factors considered in the decision-making for seeking pregnancy termination in a sample of unmarried women in Colombo, Sri Lanka. Individual qualitative interviews were conducted with 19 unmarried women seeking pregnancy terminations at a reproductive health centre in Colombo, Sri Lanka. The interviews were later analysed using qualitative content analysis. Becoming pregnant in a love relationship was predominant in this sample. Awareness of contraceptives varied and initial reaction to the pregnancy involved strong contradictory emotions. Multiple interrelated factors were considered in the decision-making for termination. Family pressure was the most prominent factor followed by the partner's qualities and attitude towards the pregnancy, economic factors and own feelings, values and future fertility. The women described that their own emotional, religious and economic reasons for continuing the pregnancy were often outweighed by their responsibility to the family, male partner and unborn child. These unmarried women's sexual and reproductive rights were limited and for many the pregnancy termination was socially unsafe. They found themselves at the interface of two value systems. Modern values allow for relationships with men prior to marriage; whereas, traditional values did not. The limited possibilities to prevent pregnancies and little hope for support if continuing the pregnancy; made women seek pregnancy termination despite own doubts. Copyright © 2010 Elsevier B.V. All rights reserved.

Illness awareness in terminal cancer patients: an Italian study.

PubMed

Corli, O; Apolone, G; Pizzuto, M; Cesaris, L; Cozzolino, A; Orsi, L; Enterri, L

2009-06-01

The amount and quality of information and awareness in cancer patients' is a topic frequently debated, but few studies have focussed on terminal patients. This is the objective of the present study that involved two different palliative home-care units in Italy, which recruited 550 terminal cancer patients. Data from patients and their caregivers was prospectively collected with special attention to information patients were provided with when their cancer was diagnosed and patients' awareness of their current health condition. In the case of the information, 67.0% of patients reported they were previously informed about their diagnosis, but only 58.0% seemed to be aware of their terminal condition. The comparison between the caregivers opinions about the level of information provided to the patients and their present awareness and what the patients really know about their own disease shows a high degree of correspondence. Some variables such as age and education level of patients were associated with patient's awareness.

Low-loss reciprocal optical terminals for two-way time-frequency transfer.

PubMed

Swann, W C; Sinclair, L C; Khader, I; Bergeron, H; Deschênes, J-D; Newbury, N R

2017-12-01

We present the design and performance of a low-cost, reciprocal, compact free-space terminal employing tip/tilt pointing compensation that enables optical two-way time-frequency transfer over free-space links across the turbulent atmosphere. The insertion loss of the terminals is ∼1.5  dB with total link losses of 15 dB, 24 dB, and 50 dB across horizontal, turbulent 2-km, 4-km, and 12-km links, respectively. The effects of turbulence on pointing control and aperture size, and their influence on the terminal design, are discussed.

Decisions Regarding Pregnancy Termination Due to β-Thalassemia Major: a Mixed-Methods Study in Sistan and Baluchestan, Iran.

PubMed

Moudi, Zahra; Miri-Moghaddam, Ebrahim

2017-06-01

In the present study, an embedded design was applied in order to conduct a one-year cross-sectional audit of chorionic villus sampling (CVS) and foetal outcomes affected by β-thalassemia major (β-TM) in a prenatal diagnosis (PND) setting. In addition, we explored the decisions regarding pregnancy termination among women whose pregnancy (or child) was affected by β-TM. In the quantitative phase, the available data in the clients' medical records were analysed, while the qualitative phase was performed using a grounded theory method. Interviews were performed with nine pregnant women who had decided against pregnancy termination despite positive CVS results, 11 mothers who had admitted their child to the thalassemia ward for blood transfusion, and 19 mothers who had received positive CVS results and had decided against pregnancy termination in the preceding year. Over one year, 18.6 % of women decided against pregnancy termination despite positive CVS results. Two main themes related to decisions against pregnancy termination emerged from the qualitative data: 1) Cognitive factors (questioning the reliability of the tests or doubts about the accuracy of the results, understanding disease recurrence, curability, perceived severity of the disease, and lack of "real-life experiences"); and 2) Sociocultural responsiveness (family opposition, responsibility before God, and self-responsiveness). All of the mentioned factors could intensify fear of abortion in couples due to possible regret, and encourage a decision against pregnancy termination.

Terminal-area STOL operating systems experiments program

NASA Technical Reports Server (NTRS)

Smith, D. W.; Watson, D.; Christensen, J. V.

1973-01-01

Information which will aid in the choice by the U.S. Government and industry of system concepts, design criteria, operating procedures for STOL aircraft and STOL ports, STOL landing guidance systems, air traffic control systems, and airborne avionics and flight control systems. Ames has developed a terminal-area STOL operating systems experiments program which is a part of the joint DOT/NASA effort is discussed. The Ames operating systems experiments program, its objectives, the program approach, the program schedule, typical experiments, the research facilities to be used, and the program status are described.

Movement or Goal: Goal Salience and Verbal Cues Affect Preschoolers' Imitation of Action Components

ERIC Educational Resources Information Center

Elsner, Birgit; Pfeifer, Caroline

2012-01-01

The impact of goal salience and verbal cues given by the model on 3- to 5-year-olds' reproduction of action components (movement or goal) was investigated in an imitation choice task. Preschoolers watched an experimenter moving a puppet up or down a ramp, terminating at one of two target objects. The target objects were either differently colored…

Immersion francaise precoce: Arts plastiques 1-7 (Early French Immersion: Plastic Arts for Grades 1-7).

ERIC Educational Resources Information Center

Burt, Andy; And Others

This curriculum guide in art education is intended for use in grades 1-7 in the early French immersion program. An introductory chapter describes the educational objectives of the art program, the role of art education in child development, general and terminal objectives, methodology, the steps in graphic evolution, and an outline of the program.…

The unique C- and N-terminal sequences of Metallothionein isoform 3 mediate growth inhibition and Vectorial active transport in MCF-7 cells.

PubMed

Voels, Brent; Wang, Liping; Sens, Donald A; Garrett, Scott H; Zhang, Ke; Somji, Seema

2017-05-25

The 3rd isoform of the metallothionein (MT3) gene family has been shown to be overexpressed in most ductal breast cancers. A previous study has shown that the stable transfection of MCF-7 cells with the MT3 gene inhibits cell growth. The goal of the present study was to determine the role of the unique C-terminal and N-terminal sequences of MT3 on phenotypic properties and gene expression profiles of MCF-7 cells. MCF-7 cells were transfected with various metallothionein gene constructs which contain the insertion or the removal of the unique MT3 C- and N-terminal domains. Global gene expression analysis was performed on the MCF-7 cells containing the various constructs and the expression of the unique C- and N- terminal domains of MT3 was correlated to phenotypic properties of the cells. The results of the present study demonstrate that the C-terminal sequence of MT3, in the absence of the N-terminal sequence, induces dome formation in MCF-7 cells, which in cell cultures is the phenotypic manifestation of a cell's ability to perform vectorial active transport. Global gene expression analysis demonstrated that the increased expression of the GAGE gene family correlated with dome formation. Expression of the C-terminal domain induced GAGE gene expression, whereas the N-terminal domain inhibited GAGE gene expression and that the effect of the N-terminal domain inhibition was dominant over the C-terminal domain of MT3. Transfection with the metallothionein 1E gene increased the expression of GAGE genes. In addition, both the C- and the N-terminal sequences of the MT3 gene had growth inhibitory properties, which correlated to an increased expression of the interferon alpha-inducible protein 6. Our study shows that the C-terminal domain of MT3 confers dome formation in MCF-7 cells and the presence of this domain induces expression of the GAGE family of genes. The differential effects of MT3 and metallothionein 1E on the expression of GAGE genes suggests unique roles of these genes in the development and progression of breast cancer. The finding that interferon alpha-inducible protein 6 expression is associated with the ability of MT3 to inhibit growth needs further investigation.

The astronomical data base and retrieval system at NASA

NASA Technical Reports Server (NTRS)

Mead, J. M.; Nagy, T. A.; Hill, R. S.; Warren, W. H., Jr.

1982-01-01

More than 250 machine-readable catalogs of stars and extended celestial objects are now available at the NASA/Goddard Space Flight Center (GSFC) as the result of over a decade of catalog acquisition, verification and documentation. Retrieval programs are described which permit the user to obtain from a remote terminal bibliographical listings for stars; to find all celestial objects from a given list that are within a defined angular separation from each object in another list; to plot celestial objects on overlays for sky survey plate areas; and to search selected catalogs for objects by criteria of position, identification number, magnitude or spectral type.

The Termination of Checking and the Role of Just Right Feelings: A Study of Obsessional Checkers Compared with Anxious and Non-clinical Controls.

PubMed

Salkovskis, Paul M; Millar, Josie; Gregory, James D; Wahl, Karina

2017-03-01

Repeated checking in OCD can be understood from a cognitive perspective as the motivated need to achieve certainty about the outcome of a potentially risky action, leading to the application of Elevated Evidence Requirements (EER) and overuse of subjective criteria. Twenty-four obsessional checkers, 22 anxious controls, and 26 non-clinical controls were interviewed about and rated recent episodes where they felt (a) they needed to check and (b) checked mainly out of habit (i.e. not obsessionally). Both subjective and objective criteria were rated as significantly more important in obsessional checkers than in controls; obsessional checkers also used more criteria overall for the termination of the check, and rated more criteria as "extremely important" than the control groups. The termination of the check was rated as more effortful for obsessional checkers than for the comparison groups. Analysis of the interview data was consistent with the ratings. Feelings of "rightness" were associated with the termination of a check for obsessional checkers but not for controls. Results were consistent with the proposal that the use of "just right feelings" to terminate checking are related to EER.

Dusty plasma sheath-like structure in the lunar terminator region

NASA Astrophysics Data System (ADS)

Popel, Sergey; Zelenyi, Lev; Atamaniuk, Barbara

2016-07-01

The main properties of the dusty plasma layer near the surface over the illuminated and dark parts of the Moon are described. They are used to realize dusty plasma behaviour and to determine electric fields over the terminator region. Possibility of the existence of a dusty plasma sheath-like structure [1] in the region of lunar terminator is shown. The electric fields excited in the terminator region are demonstrated to be on the order of 300 V/m. These electric fields can result in rise of dust particles of the size of a few micrometers up to an altitude of about 30 cm over the lunar surface that explains the effect of ``horizon glow" observed at the terminator by Surveyor lunar lander. This work was supported in part by the Presidium of the Russian Academy of Sciences (under Fundamental Research Program No. 7, ``Experimental and Theoretical Study of the Solar System Objects and Stellar Planet Systems. Transient Explosion Processes in Astrophysics" and the Russian Foundation for Basic Research (Project No. 15-02-05627-a). [1] S. I. Popel, L. M. Zelenyi, and B. Atamaniuk, Phys. Plasmas 22, 123701 (2015); doi: 10.1063/1.4937368.

Human-In-The-Loop Investigation of Interoperability Between Terminal Sequencing and Spacing, Automated Terminal Proximity Alert, and Wake-Separation Recategorization

NASA Technical Reports Server (NTRS)

Callantine, Todd J.; Bienert, Nancy; Borade, Abhay; Gabriel, Conrad; Gujral, Vimmy; Jobe, Kim; Martin, Lynne; Omar, Faisal; Prevot, Thomas; Mercer, Joey

2016-01-01

A human-in-the-loop simulation study addressed terminal-area controller-workstation interface variations for interoperability between three new capabilities being introduced by the FAA. The capabilities are Terminal Sequencing and Spacing (TSAS), Automated Terminal Proximity Alert (ATPA), and wake-separation recategorization, or 'RECAT.' TSAS provides controllers with Controller-Managed Spacing (CMS) tools, including slot markers, speed advisories, and early/late indications, together with runway assignments and sequence numbers. ATPA provides automatic monitor, warning, and alert cones to inform controllers about spacing between aircraft on approach. ATPA cones are sized according to RECAT, an improved method of specifying wake-separation standards. The objective of the study was to identify potential issues and provide recommendations for integrating TSAS with ATPA and RECAT. Participants controlled arrival traffic under seven different display configurations, then tested an 'exploratory' configuration developed with participant input. All the display conditions were workable and acceptable, but controllers strongly preferred having the CMS tools available on Feeder positions, and both CMS tools and ATPA available on Final positions. Controllers found the integrated systems favorable and liked being able to tailor configurations to individual preferences.

Heparin free dialysis in critically sick children using sustained low efficiency dialysis (SLEDD-f): A new hybrid therapy for dialysis in developing world

PubMed Central

Khare, Anshika; Dhaliwal, Maninder; Raghunathan, Veena; Wadhwani, Nikita; Nandwani, Ashish; Yadav, Dinesh Kumar; Mahapatra, Amit Kumar; Raina, Rupesh

2018-01-01

Background In critically sick adults, sustained low efficiency dialysis [SLED] appears to be better tolerated hemodynamically and outcomes seem to be comparable to CRRT. However, there is paucity of data in critically sick children. In children, two recent studies from Taiwan (n = 11) and India (n = 68) showed benefits of SLED in critically sick children. Aims and objectives The objective of the study was to look at the feasibility and tolerability of sustained low efficiency daily dialysis-filtration [SLEDD-f] in critically sick pediatric patients. Material and methods Design: Retrospective study Inclusion criteria: All pediatric patients who had undergone heparin free SLEDD-f from January 2012 to October 2017. Measurements: Data collected included demographic details, vital signs, PRISM III at admission, ventilator parameters (where applicable), number of inotropes, blood gas and electrolytes before, during, and on conclusion of SLED therapy. Technical information was gathered regarding SLEDD-f prescription and complications. Results Between 2012–2017, a total of 242 sessions of SLEDD-f were performed on 70 patients, out of which 40 children survived. The median age of patients in years was 12 (range 0.8–17 years), and the median weight was 39 kg (range 8.5–66 kg). The mean PRISM score at admission was 8.77±7.22. SLEDD-f sessions were well tolerated, with marked improvement in fluid status and acidosis. Premature terminations had to be done in 23 (9.5%) of the sessions. There were 21 sessions (8.6%) terminated due to hypotension and 2 sessions (0.8%) terminated due to circuit clotting. Post- SLEDD-f hypocalcemia occurred in 15 sessions (6.2%), post- SLEDD-f hypophosphatemia occurred in 1 session (0.4%), and post- SLEDD-f hypokalemia occurred in 17 sessions (7.0%). Conclusions This study is the largest compiled data on pediatric SLEDD-f use in critically ill patients. Our study confirms the feasibility of heparin free SLEDD-f in a larger pediatric population, and even in children weighing <20 kg on inotropic support. PMID:29698409

Range Safety for an Autonomous Flight Safety System

NASA Technical Reports Server (NTRS)

Lanzi, Raymond J.; Simpson, James C.

2010-01-01

The Range Safety Algorithm software encapsulates the various constructs and algorithms required to accomplish Time Space Position Information (TSPI) data management from multiple tracking sources, autonomous mission mode detection and management, and flight-termination mission rule evaluation. The software evaluates various user-configurable rule sets that govern the qualification of TSPI data sources, provides a prelaunch autonomous hold-launch function, performs the flight-monitoring-and-termination functions, and performs end-of-mission safing

Design of an adaptive super-twisting decoupled terminal sliding mode control scheme for a class of fourth-order systems.

PubMed

Ashtiani Haghighi, Donya; Mobayen, Saleh

2018-04-01

This paper proposes an adaptive super-twisting decoupled terminal sliding mode control technique for a class of fourth-order systems. The adaptive-tuning law eliminates the requirement of the knowledge about the upper bounds of external perturbations. Using the proposed control procedure, the state variables of cart-pole system are converged to decoupled terminal sliding surfaces and their equilibrium points in the finite time. Moreover, via the super-twisting algorithm, the chattering phenomenon is avoided without affecting the control performance. The numerical results demonstrate the high stabilization accuracy and lower performance indices values of the suggested method over the other ones. The simulation results on the cart-pole system as well as experimental validations demonstrate that the proposed control technique exhibits a reasonable performance in comparison with the other methods. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.

Neural Network Assisted Inverse Dynamic Guidance for Terminally Constrained Entry Flight

PubMed Central

Chen, Wanchun

2014-01-01

This paper presents a neural network assisted entry guidance law that is designed by applying Bézier approximation. It is shown that a fully constrained approximation of a reference trajectory can be made by using the Bézier curve. Applying this approximation, an inverse dynamic system for an entry flight is solved to generate guidance command. The guidance solution thus gotten ensures terminal constraints for position, flight path, and azimuth angle. In order to ensure terminal velocity constraint, a prediction of the terminal velocity is required, based on which, the approximated Bézier curve is adjusted. An artificial neural network is used for this prediction of the terminal velocity. The method enables faster implementation in achieving fully constrained entry flight. Results from simulations indicate improved performance of the neural network assisted method. The scheme is expected to have prospect for further research on automated onboard control of terminal velocity for both reentry and terminal guidance laws. PMID:24723821

Clostridium Difficile Infection in Acute Care Hospitals: Systematic Review and Best Practices for Prevention.

PubMed

Louh, Irene K; Greendyke, William G; Hermann, Emilia A; Davidson, Karina W; Falzon, Louise; Vawdrey, David K; Shaffer, Jonathan A; Calfee, David P; Furuya, E Yoko; Ting, Henry H

2017-04-01

OBJECTIVE Prevention of Clostridium difficile infection (CDI) in acute-care hospitals is a priority for hospitals and clinicians. We performed a qualitative systematic review to update the evidence on interventions to prevent CDI published since 2009. DESIGN We searched Ovid, MEDLINE, EMBASE, The Cochrane Library, CINAHL, the ISI Web of Knowledge, and grey literature databases from January 1, 2009 to August 1, 2015. SETTING We included studies performed in acute-care hospitals. PATIENTS OR PARTICIPANTS We included studies conducted on hospitalized patients that investigated the impact of specific interventions on CDI rates. INTERVENTIONS We used the QI-Minimum Quality Criteria Set (QI-MQCS) to assess the quality of included studies. Interventions were grouped thematically: environmental disinfection, antimicrobial stewardship, hand hygiene, chlorhexidine bathing, probiotics, bundled approaches, and others. A meta-analysis was performed when possible. RESULTS Of 3,236 articles screened, 261 met the criteria for full-text review and 46 studies were ultimately included. The average quality rating was 82% according to the QI-MQCS. The most effective interventions, resulting in a 45% to 85% reduction in CDI, included daily to twice daily disinfection of high-touch surfaces (including bed rails) and terminal cleaning of patient rooms with chlorine-based products. Bundled interventions and antimicrobial stewardship showed promise for reducing CDI rates. Chlorhexidine bathing and intensified hand-hygiene practices were not effective for reducing CDI rates. CONCLUSIONS Daily and terminal cleaning of patient rooms using chlorine-based products were most effective in reducing CDI rates in hospitals. Further studies are needed to identify the components of bundled interventions that reduce CDI rates. Infect Control Hosp Epidemiol 2017;38:476-482.

Multimarker Strategy for Heart Failure Prognostication. Value of Neurohormonal Biomarkers: Neprilysin vs NT-proBNP.

PubMed

Bayes-Genis, Antoni; Barallat, Jaume; Galán, Amparo; de Antonio, Marta; Domingo, Mar; Zamora, Elisabet; Gastelurrutia, Paloma; Vila, Joan; Peñafiel, Judith; Gálvez-Montón, Carolina; Lupón, Josep

2015-12-01

Neprilysin breaks down numerous vasoactive peptides. The soluble form of neprilysin, which was recently identified in heart failure, is associated with cardiovascular outcomes. Within a multibiomarker strategy, we directly compared soluble neprilysin and N-terminal pro-B-type natriuretic peptide as risk stratifiers in a real-life cohort of heart failure patients. Soluble neprilysin, N-terminal pro-B-type natriuretic peptide, ST2, and high-sensitivity troponin T levels were measured in 797 consecutive ambulatory heart failure patients followed up for 4.7 years. Comprehensive multivariable analyses and soluble neprilysin vs N-terminal pro-B-type natriuretic peptide head-to-head assessments of performance were performed. A primary composite endpoint included cardiovascular death or heart failure hospitalization. A secondary endpoint explored cardiovascular death alone. Median soluble neprilysin and N-terminal pro-B-type natriuretic peptide concentrations were 0.64ng/mL and 1187 ng/L, respectively. Both biomarkers significantly correlated with age (P<.001) and ST2 (P<.001), but only N-terminal pro-B-type natriuretic peptide significantly correlated with estimated glomerular filtration rate (P<.001), body mass index (P<.001), left ventricular ejection fraction (P=.02) and high-sensitivity troponin T (P<.001). In multivariable Cox regression analyses, soluble neprilysin remained independently associated with the composite endpoint (hazard ratio=1.14; 95% confidence interval, 1.02-1.27; P=.03) and cardiovascular death (hazard ratio=1.15; 95% confidence interval, 1.01-1.31; P=.04), but N-terminal pro-B-type natriuretic peptide did not. The head-to-head soluble neprilysin vs N-terminal pro-B-type natriuretic peptide comparison showed good calibration and similar discrimination and reclassification for both neurohormonal biomarkers, but only soluble neprilysin improved overall goodness-of-fit. When added to a multimarker strategy, soluble neprilysin remained an independent prognosticator, while N-terminal pro-B-type natriuretic peptide lost significance as a risk stratifier in ambulatory patients with heart failure. Both biomarkers performed similarly in head-to-head analyses. Copyright © 2015 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

Analyzing semi-competing risks data with missing cause of informative terminal event.

PubMed

Zhou, Renke; Zhu, Hong; Bondy, Melissa; Ning, Jing

2017-02-28

Cancer studies frequently yield multiple event times that correspond to landmarks in disease progression, including non-terminal events (i.e., cancer recurrence) and an informative terminal event (i.e., cancer-related death). Hence, we often observe semi-competing risks data. Work on such data has focused on scenarios in which the cause of the terminal event is known. However, in some circumstances, the information on cause for patients who experience the terminal event is missing; consequently, we are not able to differentiate an informative terminal event from a non-informative terminal event. In this article, we propose a method to handle missing data regarding the cause of an informative terminal event when analyzing the semi-competing risks data. We first consider the nonparametric estimation of the survival function for the terminal event time given missing cause-of-failure data via the expectation-maximization algorithm. We then develop an estimation method for semi-competing risks data with missing cause of the terminal event, under a pre-specified semiparametric copula model. We conduct simulation studies to investigate the performance of the proposed method. We illustrate our methodology using data from a study of early-stage breast cancer. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Normally-off AlGaN/GaN-based MOS-HEMT with self-terminating TMAH wet recess etching

NASA Astrophysics Data System (ADS)

Son, Dong-Hyeok; Jo, Young-Woo; Won, Chul-Ho; Lee, Jun-Hyeok; Seo, Jae Hwa; Lee, Sang-Heung; Lim, Jong-Won; Kim, Ji Heon; Kang, In Man; Cristoloveanu, Sorin; Lee, Jung-Hee

2018-03-01

Normally-off AlGaN/GaN-based MOS-HEMT has been fabricated by utilizing damage-free self-terminating tetramethyl ammonium hydroxide (TMAH) recess etching. The device exhibited a threshold voltage of +2.0 V with good uniformity, extremely small hysteresis of ∼20 mV, and maximum drain current of 210 mA/mm. The device also exhibited excellent off-state performances, such as breakdown voltage of ∼800 V with off-state leakage current as low as ∼10-12 A and high on/off current ratio (Ion/Ioff) of 1010. These excellent device performances are believed to be due to the high quality recessed surface, provided by the simple self-terminating TMAH etching.

Performance of an Automated System for Control of Traffic in Terminal Airspace

NASA Technical Reports Server (NTRS)

Nikoleris, Tasos; Erzberger, Heinz; Paielli, Russell A.; Chu, Yung-Cheng

2016-01-01

This paper examines the performance of a system that performs automated conflict resolution and arrival scheduling for aircraft in the terminal airspace around major airports. Such a system has the potential to perform separation assurance and arrival sequencing tasks that are currently handled manually by human controllers. The performance of the system is tested against several simulated traffic scenarios that are characterized by the rate at which air traffic is metered into the terminal airspace. For each traffic scenario, the levels of performance that are examined include: number of conflicts predicted to occur, types of resolution maneuver used to resolve predicted conflicts, and the amount of delay for all flights. The simulation results indicate that the percentage of arrivals that required a maneuver that changes the flight's horizontal route ranged between 11% and 15% in all traffic scenarios. That finding has certain implications if this automated system were to be implemented simply as a decision support tool. It is also found that arrival delay due to purely wake vortex separation requirements on final approach constituted only between 29% and 35% of total arrival delay, while the remaining major portion of it is mainly due to delay back propagation effects.

Visually scoring hirsutism

PubMed Central

Yildiz, Bulent O.; Bolour, Sheila; Woods, Keslie; Moore, April; Azziz, Ricardo

2010-01-01

BACKGROUND Hirsutism is the presence of excess body or facial terminal (coarse) hair growth in females in a male-like pattern, affects 5–15% of women, and is an important sign of underlying androgen excess. Different methods are available for the assessment of hair growth in women. METHODS We conducted a literature search and analyzed the published studies that reported methods for the assessment of hair growth. We review the basic physiology of hair growth, the development of methods for visually quantifying hair growth, the comparison of these methods with objective measurements of hair growth, how hirsutism may be defined using a visual scoring method, the influence of race and ethnicity on hirsutism, and the impact of hirsutism in diagnosing androgen excess and polycystic ovary syndrome. RESULTS Objective methods for the assessment of hair growth including photographic evaluations and microscopic measurements are available but these techniques have limitations for clinical use, including a significant degree of complexity and a high cost. Alternatively, methods for visually scoring or quantifying the amount of terminal body and facial hair growth have been in use since the early 1920s; these methods are semi-quantitative at best and subject to significant inter-observer variability. The most common visual method of scoring the extent of body and facial terminal hair growth in use today is based on a modification of the method originally described by Ferriman and Gallwey in 1961 (i.e. the mFG method). CONCLUSION Overall, the mFG scoring method is a useful visual instrument for assessing excess terminal hair growth, and the presence of hirsutism, in women. PMID:19567450

Assessing total fungal concentrations on commercial passenger aircraft using mixed-effects modeling.

PubMed

McKernan, Lauralynn Taylor; Hein, Misty J; Wallingford, Kenneth M; Burge, Harriet; Herrick, Robert

2008-01-01

The primary objective of this study was to compare airborne fungal concentrations onboard commercial passenger aircraft at various in-flight times with concentrations measured inside and outside airport terminals. A secondary objective was to investigate the use of mixed-effects modeling of repeat measures from multiple sampling intervals and locations. Sequential triplicate culturable and total spore samples were collected on wide-body commercial passenger aircraft (n = 12) in the front and rear of coach class during six sampling intervals: boarding, midclimb, early cruise, midcruise, late cruise, and deplaning. Comparison samples were collected inside and outside airport terminals at the origin and destination cities. The MIXED procedure in SAS was used to model the mean and the covariance matrix of the natural log transformed fungal concentrations. Five covariance structures were tested to determine the appropriate models for analysis. Fixed effects considered included the sampling interval and, for samples obtained onboard the aircraft, location (front/rear of coach section), occupancy rate, and carbon dioxide concentrations. Overall, both total culturable and total spore fungal concentrations were low while the aircraft were in flight. No statistical difference was observed between measurements made in the front and rear sections of the coach cabin for either culturable or total spore concentrations. Both culturable and total spore concentrations were significantly higher outside the airport terminal compared with inside the airport terminal (p-value < 0.0001) and inside the aircraft (p-value < 0.0001). On the aircraft, the majority of total fungal exposure occurred during the boarding and deplaning processes, when the aircraft utilized ancillary ventilation and passenger activity was at its peak.

24 CFR 200.1520 - Termination of MAP privileges.

Code of Federal Regulations, 2010 CFR

2010-04-01

... the traditional application processing (TAP) procedure. HUD will completely reprocess all stages of... it normally performs for TAP processing. (iv) The original lender may service a transferred loan once... lender status as a result of termination, the lender's status to process transactions using TAP is...

ACTS Ka-Band Earth Stations: Technology, Performance, and Lessons Learned

NASA Technical Reports Server (NTRS)

Reinhart, Richard C.; Struharik, Steven J.; Diamond, John J.; Stewart, David

2000-01-01

The Advanced Communications Technology Satellite (ACTS) Project invested heavily in prototype Ka-band satellite ground terminals to conduct an experiments program with ACTS. The ACTS experiments program proposed to validate Ka-band satellite and ground-station technology, demonstrate future telecommunication services, demonstrate commercial viability and market acceptability of these new services, evaluate system networking and processing technology, and characterize Ka-band propagation effects, including development of techniques to mitigate signal fading. This paper will present a summary of the fixed ground terminals developed by the NASA Glenn Research Center and its industry partners, emphasizing the technology and performance of the terminals and the lessons learned throughout their 6-year operation, including the inclined orbit phase-of-operations. The fixed ground stations used for experiments by government, academic, and commercial entities used reflector-based offset-fed antenna systems with antennas ranging in size from 0.35 to 3.4 in. in diameter. Gateway earth stations included two systems referred to as the NASA Ground Station (NGS) and the Link Evaluation Terminal (LET).

External pulsed plasma propulsion and its potential for the near future

NASA Astrophysics Data System (ADS)

Bonometti, J. A.; Morton, P. J.; Schmidt, G. R.

2000-01-01

This paper examines External Pulsed Plasma Propulsion (EPPP), a propulsion concept that derives its thrust from plasma waves generated from a series of small, supercritical fission/fusion pulses behind an object in space. For spacecraft applications, a momentum transfer mechanism translates the intense plasma wave energy into a vehicle acceleration that is tolerable to the rest of the spacecraft and its crew. This propulsion concept offers extremely high performance in terms of both specific impulse (Isp) and thrust-to-weight ratio, something that other concepts based on available technology cannot do. The political concerns that suspended work on this type of system (i.e., termination of Project ORION) may now not be as insurmountable as they were in 1965. The appeal of EPPP stems from its relatively low cost and reusability, fast interplanetary transit times, safety and reliability, and independence from major technological breakthroughs. In fact, a first generation EPPP system based on modern-day technology (i.e., GABRIEL-an evolutionary framework of EPPP concepts) may very well be the only form of propulsion that could realistically be developed to perform ambitious human exploration beyond Mars in the 21st century. It could also provide the most effective approach for deterrence against collision between earth and small planetary objects-a growing concern over recent years. .

External Pulsed Plasma Propulsion and Its Potential for the Near Future

NASA Technical Reports Server (NTRS)

Bonometti, J. A.; Morton, P. J.; Schmidt, G. R.

1999-01-01

This paper examines External Pulsed Plasma Propulsion (EPPP), a propulsion concept that derives its thrust from plasma waves generated from a series of small, supercritical fission/fusion pulses behind an object in space. For spacecraft applications, a momentum transfer mechanism translates the intense plasma wave energy into a vehicle acceleration that is tolerable to the rest of the spacecraft and its crew. This propulsion concept offers extremely high performance in terms of both specific impulse (Isp) and thrust-to-weight ratio, something that other concepts based on available technology cannot do, The political concerns that suspended work on this type of system (i.e. termination of Project ORION) may now not be as insurmountable as they were in 1965. The appeal of EPPP stems from its relatively low cost and reusability, fast interplanetary transit times, safety and reliability, and independence from major technological breakthroughs. In fact, a first generation EPPP system based on modern-day technology (i.e., GABRIEL - an evolutionary framework- of EPPP concepts) may very well be the only form of propulsion that could realistically be developed to perform ambitious human exploration beyond Mars in the 21st century. It could also provide the most effective approach for deterrence against collision between earth and small planetary objects - a growing concern over recent years.

The exosome component Rrp6 is required for RNA polymerase II termination at specific targets of the Nrd1-Nab3 pathway.

PubMed

Fox, Melanie J; Gao, Hongyu; Smith-Kinnaman, Whitney R; Liu, Yunlong; Mosley, Amber L

2015-01-01

The exosome and its nuclear specific subunit Rrp6 form a 3'-5' exonuclease complex that regulates diverse aspects of RNA biology including 3' end processing and degradation of a variety of noncoding RNAs (ncRNAs) and unstable transcripts. Known targets of the nuclear exosome include short (<1000 bp) RNAPII transcripts such as small noncoding RNAs (snRNAs), cryptic unstable transcripts (CUTs), and some stable unannotated transcripts (SUTs) that are terminated by an Nrd1, Nab3, and Sen1 (NNS) dependent mechanism. NNS-dependent termination is coupled to RNA 3' end processing and/or degradation by the Rrp6/exosome in yeast. Recent work suggests Nrd1 is necessary for transcriptome surveillance, regulating promoter directionality and suppressing antisense transcription independently of, or prior to, Rrp6 activity. It remains unclear whether Rrp6 is directly involved in termination; however, Rrp6 has been implicated in the 3' end processing and degradation of ncRNA transcripts including CUTs. To determine the role of Rrp6 in NNS termination globally, we performed RNA sequencing (RNA-Seq) on total RNA and perform ChIP-exo analysis of RNA Polymerase II (RNAPII) localization. Deletion of RRP6 promotes hyper-elongation of multiple NNS-dependent transcripts resulting from both improperly processed 3' RNA ends and faulty transcript termination at specific target genes. The defects in RNAPII termination cause transcriptome-wide changes in mRNA expression through transcription interference and/or antisense repression, similar to previously reported effects of depleting Nrd1 from the nucleus. Elongated transcripts were identified within all classes of known NNS targets with the largest changes in transcription termination occurring at CUTs. Interestingly, the extended transcripts that we have detected in our studies show remarkable similarity to Nrd1-unterminated transcripts at many locations, suggesting that Rrp6 acts with the NNS complex globally to promote transcription termination in addition to 3' end RNA processing and/or degradation at specific targets.

Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates.

PubMed

Kleifeld, Oded; Doucet, Alain; Prudova, Anna; auf dem Keller, Ulrich; Gioia, Magda; Kizhakkedathu, Jayachandran N; Overall, Christopher M

2011-09-22

Analysis of the sequence and nature of protein N termini has many applications. Defining the termini of proteins for proteome annotation in the Human Proteome Project is of increasing importance. Terminomics analysis of protease cleavage sites in degradomics for substrate discovery is a key new application. Here we describe the step-by-step procedures for performing terminal amine isotopic labeling of substrates (TAILS), a 2- to 3-d (depending on method of labeling) high-throughput method to identify and distinguish protease-generated neo-N termini from mature protein N termini with all natural modifications with high confidence. TAILS uses negative selection to enrich for all N-terminal peptides and uses primary amine labeling-based quantification as the discriminating factor. Labeling is versatile and suited to many applications, including biochemical and cell culture analyses in vitro; in vivo analyses using tissue samples from animal and human sources can also be readily performed. At the protein level, N-terminal and lysine amines are blocked by dimethylation (formaldehyde/sodium cyanoborohydride) and isotopically labeled by incorporating heavy and light dimethylation reagents or stable isotope labeling with amino acids in cell culture labels. Alternatively, easy multiplex sample analysis can be achieved using amine blocking and labeling with isobaric tags for relative and absolute quantification, also known as iTRAQ. After tryptic digestion, N-terminal peptide separation is achieved using a high-molecular-weight dendritic polyglycerol aldehyde polymer that binds internal tryptic and C-terminal peptides that now have N-terminal alpha amines. The unbound naturally blocked (acetylation, cyclization, methylation and so on) or labeled mature N-terminal and neo-N-terminal peptides are recovered by ultrafiltration and analyzed by tandem mass spectrometry (MS/MS). Hierarchical substrate winnowing discriminates substrates from the background proteolysis products and non-cleaved proteins by peptide isotope quantification and bioinformatics search criteria.

Near-Bottom Turbulence and Sediment Resuspension Induced by Nonlinear Internal Waves

DTIC Science & Technology

2015-05-27

leading to benthic nepheloid layer ( BNL ) formation. OBJECTIVES The specific objectives of this now-terminated project consisted of: • Using Large...particles by the BBL-turbulence and their transport/deposition into BNLs . • Analyze field observations from the New Jersey shelf to identify the...mapping. Finally, the generated resuspended particle distributions under NLIWs, a reliable proxy of BNLs , can be used to quantify the transmission or

A software control system for the ACTS high-burst-rate link evaluation terminal

NASA Technical Reports Server (NTRS)

Reinhart, Richard C.; Daugherty, Elaine S.

1991-01-01

Control and performance monitoring of NASA's High Burst Rate Link Evaluation Terminal (HBR-LET) is accomplished by using several software control modules. Different software modules are responsible for controlling remote radio frequency (RF) instrumentation, supporting communication between a host and a remote computer, controlling the output power of the Link Evaluation Terminal and data display. Remote commanding of microwave RF instrumentation and the LET digital ground terminal allows computer control of various experiments, including bit error rate measurements. Computer communication allows system operators to transmit and receive from the Advanced Communications Technology Satellite (ACTS). Finally, the output power control software dynamically controls the uplink output power of the terminal to compensate for signal loss due to rain fade. Included is a discussion of each software module and its applications.

Grief after second-trimester termination for fetal anomaly: a qualitative study

PubMed Central

Maguire, Marguerite; Light, Alexis; Kuppermann, Miriam; Dalton, Vanessa K.; Steinauer, Jody E.; Kerns, Jennifer L.

2015-01-01

Objectives We aimed to qualitatively evaluate factors that contribute to and alleviate grief associated with termination of a pregnancy for a fetal anomaly and how that grief changes over time. Study design We conducted a longitudinal qualitative study of decision satisfaction, grief and coping among women undergoing termination (dilation and evacuation or induction termination) for fetal anomalies and other complications. We conducted three postprocedure interviews at 1–3 weeks, 3 months and 1 year. We used a generative thematic approach to analyze themes related to grief using NVivo software program. Results Of the 19 women in the overall study, 13 women’s interviews were eligible for analysis of the grief experience. Eleven women completed all three interviews, and two completed only the first interview. Themes that contributed to grief include self-blame for the diagnosis, guilt around the termination decision, social isolation related to discomfort with abortion and grief triggered by reminders of pregnancy. Social support and time are mechanisms that serve to alleviate grief. Conclusions Pregnancy termination in this context is experienced as a significant loss similar to other types of pregnancy loss and is also associated with real and perceived stigma. Women choosing termination for fetal anomalies may benefit from tailored counseling that includes dispelling misconceptions about cause of the anomaly. In addition, efforts to decrease abortion stigma and increase social support may improve women’s experiences and lessen their grief response. Implications The nature and course of grief after second-trimester termination for fetal anomaly are, as of yet, poorly understood. With improved understanding of how women grieve over time, clinicians can better recognize the significance of their patients’ suffering and offer tools to direct their grief toward positive coping. PMID:25499590

Study of automatic and manual terminal guidance and control systems for space shuttle vehicles. Volume 2: Section 4 through appendix B

NASA Technical Reports Server (NTRS)

Osder, S.; Keller, R.

1971-01-01

Guidance and control design studies that were performed for three specific space shuttle candidate vehicles are described. Three types of simulation were considered. The manual control investigations and pilot evaluations of the automatic system performance is presented. Recommendations for systems and equipment, both airborne and ground-based, necessary to flight test the guidance and control concepts for shuttlecraft terminal approach and landing are reported.

Evaluation of touch-sensitive screen tablet terminal button size and spacing accounting for effect of fingertip contact angle.

PubMed

Nishimura, T; Doi, K; Fujimoto, H

2015-08-01

Touch-sensitive screen terminals enabling intuitive operation are used as input interfaces in a wide range of fields. Tablet terminals are one of the most common devices with a touch-sensitive screen. They have a feature of good portability, enabling use under various conditions. On the other hand, they require a GUI designed to prevent decrease of usability under various conditions. For example, the angle of fingertip contact with the display changes according to finger posture during operation and how the case is held. When a human fingertip makes contact with an object, the contact area between the fingertip and contact object increases or decreases as the contact angle changes. A touch-sensitive screen detects positions using the change in capacitance of the area touched by the fingertip; hence, differences in contact area between the touch-sensitive screen and fingertip resulting from different forefinger angles during operation could possibly affect operability. However, this effect has never been studied. We therefore conducted an experiment to investigate the relationship between size/spacing and operability, while taking the effect of fingertip contact angle into account. As a result, we have been able to specify the button size and spacing conditions that enable accurate and fast operation regardless of the forefinger contact angle.

A Study on Cognitive Radio Coexisting with Cellular Systems

NASA Astrophysics Data System (ADS)

Tandai, Tomoya; Horiguchi, Tomoya; Deguchi, Noritaka; Tomizawa, Takeshi; Tomioka, Tazuko

Cognitive Radios (CRs) are expected to perform more significant role in the view of efficient utilization of the spectrum resources in the future wireless communication networks. In this paper, a cognitive radio coexisting with cellular systems is proposed. In the case that a cellular system adopts Frequency Division Duplex (FDD) as a multiplexing scheme, the proposed CR terminals communicate in local area on uplink channels of the cellular system with transmission powers that don't interfere with base stations of the cellular system. Alternatively, in the case that a cellular system adopts Time Division Duplex (TDD), the CR terminals communicate on uplink slots of the cellular system. However if mobile terminals in the cellular system are near the CR network, uplink signals from the mobile terminals may interfere with the CR communications. In order to avoid interference from the mobile terminals, the CR terminal performs carrier sense during a beginning part of uplink slot, and only when the level of detected signal is below a threshold, then the CR terminal transmits a signal during the remained period of the uplink slot. In this paper, both the single carrier CR network that uses one frequency channel of the cellular system and the multicarrier CR network that uses multiple frequency channels of the cellular system are considered. The probabilities of successful CR communications, the average throughputs of the CR communications according to the positions of the CR network, and the interference levels from cognitive radio network to base stations of the cellular system are evaluated in the computer simulation then the effectiveness of the proposed network is clarified.

New Hypervelocity Terminal Intercept Guidance Systems for Deflecting/Disrupting Hazardous Asteroids

NASA Astrophysics Data System (ADS)

Lyzhoft, Joshua Richard

Computational modeling and simulations of visual and infrared (IR) sensors are investigated for a new hypervelocity terminal guidance system of intercepting small asteroids (50 to 150 meters in diameter). Computational software tools for signal-to-noise ratio estimation of visual and IR sensors, estimation of minimum and maximum ranges of target detection, and GPU (Graphics Processing Units)-accelerated simulations of the IR-based terminal intercept guidance systems are developed. Scaled polyhedron models of known objects, such as the Rosetta mission's Comet 67P/C-G, NASA's OSIRIS-REx Bennu, and asteroid 433 Eros, are utilized in developing a GPU-based simulation tool for the IR-based terminal intercept guidance systems. A parallelized-ray tracing algorithm for simulating realistic surface-to-surface shadowing of irregular-shaped asteroids or comets is developed. Polyhedron solid-angle approximation is also considered. Using these computational models, digital image processing is investigated to determine single or multiple impact locations to assess the technical feasibility of new planetary defense mission concepts of utilizing a Hypervelocity Asteroid Intercept Vehicle (HAIV) or a Multiple Kinetic-energy Interceptor Vehicle (MKIV). Study results indicate that the IR-based guidance system outperforms the visual-based system in asteroid detection and tracking. When using an IR sensor, predicting impact locations from filtered images resulted in less jittery spacecraft control accelerations than conducting missions with a visual sensor. Infrared sensors have also the possibility to detect asteroids at greater distances, and if properly used, can aid in terminal phase guidance for proper impact location determination for the MKIV system. Emerging new topics of the Minimum Orbit Intersection Distance (MOID) estimation and the Full-Two-Body Problem (F2BP) formulation are also investigated to assess a potential near-Earth object collision risk and the proximity gravity effects of an irregular-shaped binary-asteroid target on a standoff nuclear explosion mission.

Computer-Graphics Emulation of Chemical Instrumentation: Absorption Spectrophotometers.

ERIC Educational Resources Information Center

Gilbert, D. D.; And Others

1982-01-01

Describes interactive, computer-graphics program emulating behavior of high resolution, ultraviolet-visible analog recording spectrophotometer. Graphics terminal behaves as recording absorption spectrophotometer. Objective of the emulation is study of optimization of the instrument to yield accurate absorption spectra, including…

Blast Injuries And Heterotopic Ossification

DTIC Science & Technology

2012-08-01

transfemoral amputation. Note the skin graft over the terminal portion of the residual limb. Although we advocate avoiding terminal skin grafting of...of the overlying skin graft . Fig. 2a 177 K. A. ALFIERI, J. A. FORSBERG, B. K. POTTER BONE & JOINT RESEARCH mimimum of six months prior to performing

Polynomial filter estimation of range and range rate for terminal rendezvous

NASA Technical Reports Server (NTRS)

Philips, R.

1970-01-01

A study was made of a polynomial filter for computing range rate information from CSM VHF range data. The filter's performance during the terminal phase of the rendezvous is discussed. Two modifications of the filter were also made and tested. A manual terminal rendezvous was simulated and desired accuracies were achieved for vehicles on an intercept trajectory, except for short periods following each braking maneuver when the estimated range rate was initially in error by the magnitude of the burn.

Maximum and minimum return losses from a passive two-port network terminated with a mismatched load

NASA Technical Reports Server (NTRS)

Otoshi, T. Y.

1993-01-01

This article presents an analytical method for determining the exact distance a load is required to be offset from a passive two-port network to obtain maximum or minimum return losses from the terminated two-port network. Equations are derived in terms of two-port network S-parameters and load reflection coefficient. The equations are useful for predicting worst-case performances of some types of networks that are terminated with offset short-circuit loads.

Phenylethynyl amine

NASA Technical Reports Server (NTRS)

Hergenrother, Paul M. (Inventor); Bryant, Robert G. (Inventor); Jensen, Brian J. (Inventor); Havens, Stephen J. (Inventor)

1997-01-01

Four phenylethynyl amine compounds--3 and 4-aminophenoxy-4'-phenylethynylbenzophenone, and 3 and 4-amino-4'-phenylethynylbenzophenone--were readily prepared and were used to endcap imide oligomers. Phenylethynyl-terminated amide acid oligomers and phenylethynyl-terminated imide oligomers with various molecular weights and compositions were prepared and characterized. These oligomers were cured at 300.degree. C. to 400.degree. C. to provide crosslinked polyimides with excellent solvent resistance, high strength and modulus and good high temperature properties. Adhesive panels, composites, films and moldings from these phenylethynyl terminated imide oligomers gave excellent mechanical performance.

Simulating the performance of adaptive optics techniques on FSO communications through the atmosphere

NASA Astrophysics Data System (ADS)

Martínez, Noelia; Rodríguez Ramos, Luis Fernando; Sodnik, Zoran

2017-08-01

The Optical Ground Station (OGS), installed in the Teide Observatory since 1995, was built as part of ESA efforts in the research field of satellite optical communications to test laser telecommunication terminals on board of satellites in Low Earth Orbit and Geostationary Orbit. As far as one side of the link is settled on the Earth, the laser beam (either on the uplink or on the downlink) has to bear with the atmospheric turbulence. Within the framework of designing an Adaptive Optics system to improve the performance of the Free-Space Optical Communications at the OGS, turbulence conditions regarding uplink and downlink have been simulated within the OOMAO (Object-Oriented Matlab Adaptive Optics) Toolbox as well as the possible utilization of a Laser Guide Star to measure the wavefront in this context. Simulations have been carried out by reducing available atmospheric profiles regarding both night-time and day-time measurements and by having into account possible seasonal changes. An AO proposal to reduce atmospheric aberrations and, therefore, ameliorate FSO links performance is presented and analysed in this paper

Experience of Thai women in Bangkok with Norplant-2 implants.

PubMed

Chompootaweep, S; Kochagarn, E; Tang-Usaha, J; Theppitaksak, B; Dusitsin, N

1998-10-01

A prospective study of the Norplant-2 contraceptive subdermal implant system was conducted in Bangkok, Thailand. The objective of the study was to evaluate the efficacy, adverse effects, and overall acceptability of Norplant-2 implants. A total of 140 women were enrolled in a 3-year clinical trial. The mean age was 29 years. Of all the acceptors, 70% had completed primary school. The continuation rates at years 1, 2, and 3 were, respectively, 94%, 89%, and 83%. No accidental pregnancies occurred throughout the 3 years of use in this study. Personal reasons were the leading cause for termination of Norplant-2 implant use. The 3-year cumulative termination rate for personal reasons was 7.2%. These personal reasons were divorce, husband having vasectomy, and moving away from the study area. The other leading cause for termination was medical reasons; acne, headache, and pain at the implant site were the complaints. The termination rate for medical reasons in year 3 of the study was 4.6%. Prolonged menstrual flow was the other main reason for termination. The 3-year cumulative termination rate for menstrual irregularities was 3.8%. In this study, the cumulative termination for planned pregnancy at the end of the year 3 was only 1.6%. The incidence of difficult removals was 8%. Breakage of the rods on removal was encountered in the majority of these cases. The study findings presented suggest that the Norplant-2 implants are highly effective with high continuation rates. The Norplant-2 system could become another choice of long acting reversible contraception for Thai women.

Compact Termination for Structural Soft-goods

NASA Technical Reports Server (NTRS)

Wilkes, Robert, Jr.

2013-01-01

Glass fiber is unique in its ability to withstand atomic oxygen and ultraviolet radiation in-space environments. However, glass fiber is also difficult to terminate by traditional methods without decreasing its strength significantly. Glass fiber products are especially sensitive to bend radius, and do not work very well with traditional 'sewn loop on pin' type connections. As with most composites, getting applied loads from a metallic structure into the webbing without stress concentrations is the key to a successful design. A potted end termination has been shown in some preliminary work to out-perform traditional termination methods. It was proposed to conduct a series of tensile tests on structural webbing or cord to determine the optimum potting geometry, and to then be able to estimate a weight and volume savings over traditional sewn-overa- pin connections. During the course of the investigation into potted end terminations for glass fiber webbing, a new and innovative connection was developed that has lower weight, reduced fabrication time, and superior thermal tolerance over the metallic end terminations that were to be optimized in the original proposal. This end termination essentially transitions the flexible glass fiber webbing into a rigid fiberglass termination, which can be bolted/fastened with traditional methods

Dynamic testing of a non-proprietary, high-tension, cable end terminal system.

DOT National Transportation Integrated Search

2014-03-01

Two bogie tests were conducted on a high-tension cable end terminal to evaluate the performance of a new design. The : main goals of the new design were to promote quick cable release times, to retain the cable release lever during impact, to : susta...

7 CFR 1755.910 - RUS specification for outside plant housings and serving area interface systems.

Code of Federal Regulations, 2012 CFR

2012-01-01

... requirements are interrelated to several tests designed to determine the performance aspects of terminals and... environments. Included are the mechanical, electrical, and environmental requirements, desired design features, and test methods for evaluation of the product. (2) The housing and terminal requirements reflect the...

7 CFR 1755.910 - RUS specification for outside plant housings and serving area interface systems.

Code of Federal Regulations, 2013 CFR

2013-01-01

... requirements are interrelated to several tests designed to determine the performance aspects of terminals and... environments. Included are the mechanical, electrical, and environmental requirements, desired design features, and test methods for evaluation of the product. (2) The housing and terminal requirements reflect the...

7 CFR 1755.910 - RUS specification for outside plant housings and serving area interface systems.

Code of Federal Regulations, 2014 CFR

2014-01-01

... requirements are interrelated to several tests designed to determine the performance aspects of terminals and... environments. Included are the mechanical, electrical, and environmental requirements, desired design features, and test methods for evaluation of the product. (2) The housing and terminal requirements reflect the...

7 CFR 1755.910 - RUS specification for outside plant housings and serving area interface systems.

Code of Federal Regulations, 2011 CFR

2011-01-01

... requirements are interrelated to several tests designed to determine the performance aspects of terminals and... environments. Included are the mechanical, electrical, and environmental requirements, desired design features, and test methods for evaluation of the product. (2) The housing and terminal requirements reflect the...

Smart truck driver assistant : a cost effective solution for real time management of container delivery to trucks.

DOT National Transportation Integrated Search

2015-12-01

The twin ports of Los Angeles and Long Beach are two of the busiest ports in the country. The marine terminals at these ports are under tremendous pressure to enhance their performance levels. One major issue in the terminals' productivity and perfor...

40 CFR 60.500 - Applicability and designation of affected facility.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Performance for Bulk Gasoline Terminals § 60.500 Applicability and designation of affected facility. (a) The... bulk gasoline terminal which deliver liquid product into gasoline tank trucks. (b) Each facility under... technologies (BDT). The numerical emission limits in this standard are expressed in terms of total organic...

40 CFR 60.500 - Applicability and designation of affected facility.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Performance for Bulk Gasoline Terminals § 60.500 Applicability and designation of affected facility. (a) The... bulk gasoline terminal which deliver liquid product into gasoline tank trucks. (b) Each facility under... technologies (BDT). The numerical emission limits in this standard are expressed in terms of total organic...

5 CFR 575.111 - Termination of a service agreement.

Code of Federal Regulations, 2010 CFR

2010-01-01

...., for unacceptable performance or conduct), if the employee receives a rating of record (or an official... management needs of the agency. For example, an agency may terminate a service agreement when the employee's... incentive payments, or when the agency assigns the employee to a different position (if the different...

5 CFR 575.211 - Termination of a service agreement.

Code of Federal Regulations, 2010 CFR

2010-01-01

...., for unacceptable performance or conduct), if the employee receives a rating of record (or an official... needs of the agency. For example, an agency may terminate a service agreement when the employee's... incentive payments, or when the agency assigns the employee to a different position (if the different...

Development of robots and application to industrial processes

NASA Technical Reports Server (NTRS)

Palm, W. J.; Liscano, R.

1984-01-01

An algorithm is presented for using a robot system with a single camera to position in three-dimensional space a slender object for insertion into a hole; for example, an electrical pin-type termination into a connector hole. The algorithm relies on a control-configured end effector to achieve the required horizontal translations and rotational motion, and it does not require camera calibration. A force sensor in each fingertip is integrated with the vision system to allow the robot to teach itself new reference points when different connectors and pins are used. Variability in the grasped orientation and position of the pin can be accomodated with the sensor system. Performance tests show that the system is feasible. More work is needed to determine more precisely the effects of lighting levels and lighting direction.

CAMAC: A Unique Application with a Pocket Terminal.

DTIC Science & Technology

1982-09-16

POCKET TERMINAL S. PERFORMING ORG. REPORT NUMSIER I. AUTWOR(o) S. CONTRACT OR GRANT NUMU41’e() A.D. Elmond S. PERFORMING ORGANIZATION NAME AND ADORIESS 10...port of any CAMAC crate. In addition to being a maintenance device, the HHTT is a " smart " device that can control operations in a CAMAC crate. The...system LSI 11/23 microprocessor through an Asynchronous Serial Port (ASP) interface module. This ASP interface consists of: 1) Crystal Clock 2) MIK -Bus

Flight performance of the TCV B-737 airplane at Montreal/Dorval International Airport, Montreal, Canada, using TRSB/MLS guidance

NASA Technical Reports Server (NTRS)

White, W. F.; Clark, L. V.

1980-01-01

The NASA terminal configured vehicle B-737 was flown in support of the world wide FAA demonstration of the time reference scanning beam microwave landing system. A summary of the flight performance of the TCV airplane during demonstration automatic approaches and landings while utilizing TRSB/MLS guidance is presented. The TRSB/MLS provided the terminal area guidance necessary for automatically flying curved, noise abatement type approaches and landings with short finals.

Aesthetic bridge rails, transitions, and terminals for park roads and parkways

DOT National Transportation Integrated Search

1990-05-01

The objective of this project was to test aesthetic bridge rails for park roads, parkways, and other roads under Federal jurisdiction. Four designs were analyzed and evaluated: the Modified (Kansas Corral bridge rail, the Forest Service glulam bridge...

Conflict Termination--Transitioning from Warrior to Constable: A Primer

DTIC Science & Technology

1992-04-15

historical or artistic interest; works of art, manuscripts, books, and other objects of artistic, historical, or archaeological interest; scientific ... collections and important collections of books or archives, or reproductions of the property defined above. Buildings used for cultural or religious

Louisiana offshore terminal authority environmental monitoring 2001-2002 marine/estuarine : Part 2.

DOT National Transportation Integrated Search

2002-09-01

The objectives of the monitoring program are (1) to maintain seasonal environmental and ecological data so that conditions existing during operations can be related to historical baseline conditions; (2) to detect during the operation of the deepwate...

Telomere healing following DNA polymerase arrest-induced breakages is likely the main mechanism generating chromosome 4p terminal deletions.

PubMed

Hannes, Femke; Van Houdt, Jeroen; Quarrell, Oliver W; Poot, Martin; Hochstenbach, Ron; Fryns, Jean-Pierre; Vermeesch, Joris R

2010-12-01

Constitutional developmental disorders are frequently caused by terminal chromosomal deletions. The mechanisms and/or architectural features that might underlie those chromosome breakages remain largely unexplored. Because telomeres are the vital DNA protein complexes stabilizing linear chromosomes against chromosome degradation, fusion, and incomplete replication, those terminal-deleted chromosomes acquired new telomeres either by telomere healing or by telomere capture. To unravel the mechanisms leading to chromosomal breakage and healing, we sequenced nine chromosome 4p terminal deletion boundaries. A computational analysis of the breakpoint flanking region, including 12 previously published pure terminal breakage sites, was performed in order to identify architectural features that might be involved in this process. All terminal 4p truncations were likely stabilized by telomerase-mediated telomere healing. In the majority of breakpoints multiple genetic elements have a potential to induce secondary structures and an enrichment in replication stalling site motifs were identified. These findings suggest DNA replication stalling-induced chromosome breakage during early development is the first mechanistic step leading toward terminal deletion syndromes. © 2010 Wiley-Liss, Inc.

A stochastic discrete optimization model for designing container terminal facilities

NASA Astrophysics Data System (ADS)

Zukhruf, Febri; Frazila, Russ Bona; Burhani, Jzolanda Tsavalista

2017-11-01

As uncertainty essentially affect the total transportation cost, it remains important in the container terminal that incorporates several modes and transshipments process. This paper then presents a stochastic discrete optimization model for designing the container terminal, which involves the decision of facilities improvement action. The container terminal operation model is constructed by accounting the variation of demand and facilities performance. In addition, for illustrating the conflicting issue that practically raises in the terminal operation, the model also takes into account the possible increment delay of facilities due to the increasing number of equipment, especially the container truck. Those variations expectantly reflect the uncertainty issue in the container terminal operation. A Monte Carlo simulation is invoked to propagate the variations by following the observed distribution. The problem is constructed within the framework of the combinatorial optimization problem for investigating the optimal decision of facilities improvement. A new variant of glow-worm swarm optimization (GSO) is thus proposed for solving the optimization, which is rarely explored in the transportation field. The model applicability is tested by considering the actual characteristics of the container terminal.

An experimental paradigm to compare motor performance under laboratory and under everyday-like conditions.

PubMed

Bock, Otmar; Hagemann, Anne

2010-10-30

Research findings on human motor skills may not necessarily hold in everyday life, since laboratory and everyday scenarios typically differ with respect to the subjects' attention to the skill, their motivation to perform at their best, the goals they try to achieve, and the mode of movement initiation - extrinsic versus intrinsic. Here we present an experimental approach which can be used to substantiate the hypothesized effects of laboratory (L) versus everyday (E) settings on one type of motor skill, i.e., manual prehension. This approach is based on two tasks: In task L, subjects are told that they will participate in an experiment on grasping, and are instructed to seize and move a lever upon appearance of a visual target. In task E, they are told that they will play a computer game, and they have to seize and move the lever in order to proceed from one game level to the next. Both tasks include prehension movements from the same starting position and object to the same terminal position and object; movements differ only in their behavioural context. We exemplify the utility of our approach with a preliminary analysis of kinematic and force data. It shows that the two tasks differ with respect to several performance measures, and that some performance measures make independent contributions to that difference. The existence of independent contributions suggests that behavioural context may influence prehension via several distinct routes. Our approach can be used for comprehensive analyses of the context-dependence of motor skills in various reference groups. Copyright © 2010 Elsevier B.V. All rights reserved.

Purification and Crystallization of Murine Myostatin: A Negative Regulator of Muscle Mass

NASA Technical Reports Server (NTRS)

Hong, Young S.; Adamek, Daniel; Bridge, Kristi; Malone, Christine C.; Young, Ronald B.; Miller, Teresa; Karr, Laurel

2004-01-01

Myostatin (MSTN) has been crystallized and its preliminary X-ray diffraction data were collected. MSTN is a negative regulator of muscle growt/differentiation and suppressor of fat accumulation. It is a member of TGF-b family of proteins. Like other members of this family, the regulation of MSTN is critically tied to its process of maturation. This process involves the formation of a homodimer followed by two proteolytic steps. The first proteolytic cleavage produces a species where the n-terminal portion of the dimer is covalently separated from, but remains non-covalently bound to, the c-terminal, functional, portion of the protein. The protein is activated upon removal of the n-terminal "pro-segment" by a second n-terminal proteolytic cut by BMP-1 in vivo, or by acid treatment in vitro. Understanding the structural nature and physical interactions involved in these regulatory processes is the objective of our studies. Murine MSTN was purified from culture media of genetically engineered Chinese Hamster Ovary cells by multicolumn purification process and crystallized using the vapor diffusion method.

Physiological Effects of Acceleration Observed During a Centrifuge Study of Pilot Performance

NASA Technical Reports Server (NTRS)

Smedal, Harald A.; Creer, Brent Y.; Wingrove, Rodney C.

1960-01-01

An investigation was conducted by the National Aeronautics and Space Administration, Ames Research Center, and the Naval Air Development Center, Aviation Medical Acceleration Laboratory, to study the effects of acceleration on pilot performance and to obtain some meaningful data for use in establishing tolerance to acceleration levels. The flight simulator used in the study was the Johnsville centrifuge operated as a closed loop system. The pilot was required to perform a control task in various sustained acceleration fields typical of those that Might be encountered by a pilot flying an entry vehicle in which he is seated in a forward-facing position. A special restraint system was developed and designed to increase the pilot's tolerance to these accelerations. The results of this study demonstrated that a well-trained subject, such as a test pilot, can adequately carry out a control task during moderately high accelerations for prolonged periods of time. The maximum levels of acceleration tolerated were approximately 6 times that of gravity for approximately 6 minutes, and varied slightly with the acceleration direction. The tolerance runs were in each case terminated by the subject. In all but two instances, the cause was extreme fatigue. On two occasions the subject terminated the run when he "grayed out." Although there were subjective and objective findings involving the visual and cardiovascular systems, the respiratory system yielded the more critical limiting factors. It would appear that these limiting factors were less severe during the "eyeballs-out" accelerations when compared with the "eyeballs-in" accelerations. These findings are explained on the basis of the influence that the inertial forces of acceleration have on the mechanics of respiration. A condensed version of this report was presented at the Annual Meeting of the Aerospace Medical Association, Miami Beach, May 5-11, 1960, in a paper entitled "Ability of Pilots to Perform a Control Task in Various Sustained Acceleration Fields."

Updating the profile of C-terminal MECP2 deletions in Rett syndrome

PubMed Central

Bebbington, A; Percy, A; Christodoulou, J; Ravine, D; Ho, G; Jacoby, P; Anderson, A; Pineda, M; Ben Zeev, B; Bahi-Buisson, N; Smeets, E; Leonard, H

2014-01-01

Objectives This study aimed to compare the phenotype of Rett syndrome cases with C-terminal deletions to that of cases with different MECP2 mutations and to examine the phenotypic variation within C-terminal deletions. Methods Cases were selected from InterRett, an international database and from the population-based Australian Rett Syndrome Database. Cases (n=832) were included if they had a pathogenic MECP2 mutation in which the nature of the amino acid change was known. Three severity scale systems were used, and individual aspects of the phenotype were also compared. Results Lower severity was associated with C-terminal deletions (n=79) compared to all other MECP2 mutations (e.g. Pineda scale C-terminals mean 15.0 (95% CI 14.0–16.0) vs 16.2 (15.9–16.5). Cases with C-terminal deletions were more likely to have a normal head circumference (odds ratio 3.22, 95% CI 1.53 – 6.79) and weight (odds ratio 2.97, 95% CI 1.25–5.76). Onset of stereotypies tended to be later (median age 2.5 years vs 2 years, p<0.001 from survival analysis), and age of learning to walk tended to be earlier (median age 1.6 years vs 2 years, p=0.002 from survival analysis). Those with C-terminal deletions occurring later in the region had lower average severity scores than those occurring earlier in the region. Conclusion In terms of overall severity C-terminal deletion cases would appear to be in the middle of the range. In terms of individual aspects of phenotype growth and ability to ambulate appear to be particular strengths. By pooling data internationally this study has achieved the case numbers to provide a phenotypic profile of C-terminal deletions in Rett syndrome. PMID:19914908

Development of a new integrated local trajectory planning and tracking control framework for autonomous ground vehicles

NASA Astrophysics Data System (ADS)

Li, Xiaohui; Sun, Zhenping; Cao, Dongpu; Liu, Daxue; He, Hangen

2017-03-01

This study proposes a novel integrated local trajectory planning and tracking control (ILTPTC) framework for autonomous vehicles driving along a reference path with obstacles avoidance. For this ILTPTC framework, an efficient state-space sampling-based trajectory planning scheme is employed to smoothly follow the reference path. A model-based predictive path generation algorithm is applied to produce a set of smooth and kinematically-feasible paths connecting the initial state with the sampling terminal states. A velocity control law is then designed to assign a speed value at each of the points along the generated paths. An objective function considering both safety and comfort performance is carefully formulated for assessing the generated trajectories and selecting the optimal one. For accurately tracking the optimal trajectory while overcoming external disturbances and model uncertainties, a combined feedforward and feedback controller is developed. Both simulation analyses and vehicle testing are performed to verify the effectiveness of the proposed ILTPTC framework, and future research is also briefly discussed.

Abortion experiences among Zanzibari women: a chain-referral sampling study.

PubMed

Norris, Alison; Harrington, Bryna J; Grossman, Daniel; Hemed, Maryam; Hindin, Michelle J

2016-03-11

In Zanzibar, a semi-autonomous region of Tanzania, induced abortion is illegal but common, and fewer than 12% of married reproductive-aged women use modern contraception. As part of a multi-method study about contraception and consequences of unwanted pregnancies, the objective of this study was to understand the experiences of Zanzibari women who terminated pregnancies. The cross-sectional study was set in Zanzibar, Tanzania. Participants were a community-based sample of women who had terminated pregnancies. We carried out semi-structured interviews with 45 women recruited via chain-referral sampling. We report the characteristics of women who have had abortions, the reasons they had abortions, and the methods used to terminate their pregnancies. Women in Zanzibar terminate pregnancies that are unwanted for a range of reasons, at various points in their reproductive lives, and using multiple methods. While clinical methods were most effective, nearly half of our participants successfully terminated a pregnancy using non-clinical methods and very few had complications requiring post abortion care (PAC). Even in settings where abortion is illegal, some women experience illegal abortions without adverse health consequences, what we might call 'safer' unsafe abortions; these kinds of abortion experiences can be missed in studies about abortion conducted among women seeking PAC in hospitals.

Wavelet-based compression of pathological images for telemedicine applications

NASA Astrophysics Data System (ADS)

Chen, Chang W.; Jiang, Jianfei; Zheng, Zhiyong; Wu, Xue G.; Yu, Lun

2000-05-01

In this paper, we present the performance evaluation of wavelet-based coding techniques as applied to the compression of pathological images for application in an Internet-based telemedicine system. We first study how well suited the wavelet-based coding is as it applies to the compression of pathological images, since these images often contain fine textures that are often critical to the diagnosis of potential diseases. We compare the wavelet-based compression with the DCT-based JPEG compression in the DICOM standard for medical imaging applications. Both objective and subjective measures have been studied in the evaluation of compression performance. These studies are performed in close collaboration with expert pathologists who have conducted the evaluation of the compressed pathological images and communication engineers and information scientists who designed the proposed telemedicine system. These performance evaluations have shown that the wavelet-based coding is suitable for the compression of various pathological images and can be integrated well with the Internet-based telemedicine systems. A prototype of the proposed telemedicine system has been developed in which the wavelet-based coding is adopted for the compression to achieve bandwidth efficient transmission and therefore speed up the communications between the remote terminal and the central server of the telemedicine system.

Changes in Cerebral Hemodynamics during Complex Motor Learning by Character Entry into Touch-Screen Terminals.

PubMed

Sagari, Akira; Iso, Naoki; Moriuchi, Takefumi; Ogahara, Kakuya; Kitajima, Eiji; Tanaka, Koji; Tabira, Takayuki; Higashi, Toshio

2015-01-01

Studies of cerebral hemodynamics during motor learning have mostly focused on neurorehabilitation interventions and their effectiveness. However, only a few imaging studies of motor learning and the underlying complex cognitive processes have been performed. We measured cerebral hemodynamics using near-infrared spectroscopy (NIRS) in relation to acquisition patterns of motor skills in healthy subjects using character entry into a touch-screen terminal. Twenty healthy, right-handed subjects who had no previous experience with character entry using a touch-screen terminal participated in this study. They were asked to enter the characters of a randomly formed Japanese syllabary into the touch-screen terminal. All subjects performed the task with their right thumb for 15 s alternating with 25 s of rest for 30 repetitions. Performance was calculated by subtracting the number of incorrect answers from the number of correct answers, and gains in motor skills were evaluated according to the changes in performance across cycles. Behavioral and oxygenated hemoglobin concentration changes across task cycles were analyzed using Spearman's rank correlations. Performance correlated positively with task cycle, thus confirming motor learning. Hemodynamic activation over the left sensorimotor cortex (SMC) showed a positive correlation with task cycle, whereas activations over the right prefrontal cortex (PFC) and supplementary motor area (SMA) showed negative correlations. We suggest that increases in finger momentum with motor learning are reflected in the activity of the left SMC. We further speculate that the right PFC and SMA were activated during the early phases of motor learning, and that this activity was attenuated with learning progress.

In-Operando Spatial Imaging of Edge Termination Electric Fields in GaN Vertical p-n Junction Diodes

DOE PAGES

Leonard, Francois; Dickerson, J. R.; King, M. P.; ...

2016-05-03

Control of electric fields with edge terminations is critical to maximize the performance of high-power electronic devices. We proposed a variety of edge termination designs which makes the optimization of such designs challenging due to many parameters that impact their effectiveness. And while modeling has recently allowed new insight into the detailed workings of edge terminations, the experimental verification of the design effectiveness is usually done through indirect means, such as the impact on breakdown voltages. In this letter, we use scanning photocurrent microscopy to spatially map the electric fields in vertical GaN p-n junction diodes in operando. We alsomore » reveal the complex behavior of seemingly simple edge termination designs, and show how the device breakdown voltage correlates with the electric field behavior. Modeling suggests that an incomplete compensation of the p-type layer in the edge termination creates a bilayer structure that leads to these effects, with variations that significantly impact the breakdown voltage.« less

Nurses' views on their involvement in euthanasia: a qualitative study in Flanders (Belgium)

PubMed Central

de Casterlé, B Dierckx; Verpoort, C; De Bal, N; Gastmans, C

2006-01-01

Background Although nurses worldwide are confronted with euthanasia requests from patients, the views of palliative care nurses on their involvement in euthanasia remain unclear. Objectives In depth exploration of the views of palliative care nurses on their involvement in the entire care process surrounding euthanasia. Design A qualitative Grounded Theory strategy was used. Setting and participants In anticipation of new Belgian legislation on euthanasia, we conducted semistructured interviews with 12 nurses working in a palliative care setting in the province of Vlaams‐Brabant (Belgium). Results Palliative care nurses believed unanimously that they have an important role in the process of caring for a patient who requests euthanasia, a role that is not limited to assisting the physician when he is administering life terminating drugs. Nurses' involvement starts when the patient requests euthanasia and ends with supporting the patient's relatives and healthcare colleagues after the potential life terminating act. Nurses stressed the importance of having an open mind and of using palliative techniques, also offering a contextual understanding of the patient's request in the decision making process. Concerning the actual act of performing euthanasia, palliative care nurses saw their role primarily as assisting the patient, the patient's family, and the physician by being present, even if they could not reconcile themselves with actually performing euthanasia. Conclusions Based on their professional nursing expertise and unique relationship with the patient, nurses participating as full members of the interdisciplinary expert team are in a key position to provide valuable care to patients requesting euthanasia. PMID:16574869

Recognition and treatment of unstable supraventricular tachycardia by pediatric residents in a simulation scenario.

PubMed

Shilkofski, Nicole A; Nelson, Kristen L; Hunt, Elizabeth A

2008-01-01

Supraventricular tachycardia (SVT) is the most frequent tachydysrhythmia in children. SVT with hemodynamic compromise should be terminated by immediate electrical cardioversion. Study objectives were to: (1) establish time to recognition and cardioversion of simulated unstable SVT; and (2) document delays and mistakes made during cardioversion. Ten teams of pediatric residents were presented with an unresponsive "patient" (Laerdal SimMan) in unstable SVT. Actions of team members and simulator timestamps of key events were recorded. A retrospective review of events and time logs was performed with primary outcome measure of time to successful cardioversion. Median time to cardioversion was 8.9 minutes (range, 5.3 minutes to unsuccessful scenario terminated at 15 minutes). In 20% of scenarios, the patient was never cardioverted. Ninety percent of teams administered adenosine, but 44% of attempts demonstrated incorrect administration technique. Other maneuvers before cardioversion: 70% administered fluid, 60% attempted vagal maneuvers, 30% requested electrocardiogram, 30% requested antiarrhythmics. In 20% of scenarios, the rhythm was misidentified. When cardioversion was performed, 25% failed to use gel, 37.5% failed to synchronize, 25% used inappropriate energy doses. In 60% of scenarios, no oxygen was administered. In 90% there was no assignment of Glasgow Coma Scale, and no assessment of mental status in 30%. In 60% perfusion was not assessed. Median time to cardioversion of 8.9 minutes is inconsistent with AHA recommendations for treatment of unstable SVT with "immediate cardioversion." Delays were secondary to lack of recognition of "unstable" SVT, due to failure to assess perfusion and mental status. Errors encountered during simulation identify curriculum reform targets.

High performance addition-type thermoplastics (ATTs) - Evidence for the formation of a Diels-Alder adduct in the reaction of an acetylene-terminated material and a bismaleimide

NASA Technical Reports Server (NTRS)

Pater, R. H.; Soucek, M. D.; Chang, A. C.; Partos, R. D.

1991-01-01

Recently, the concept and demonstration of a new versatile synthetic reaction for making a large number of high-performance addition-type thermoplastics (ATTs) were reported. The synthesis shows promise for providing polymers having an attractive combination of easy processability, good toughness, respectable high temperature mechanical performance, and excellent thermo-oxidative stability. The new chemistry involves the reaction of an acetylene-terminated material with a bismaleimide or benzoquinone. In order to clarify the reaction mechanism, model compound studies were undertaken in solutions as well as in the solid state. The reaction products were purified by flash chromatography and characterized by conventional analytical techniques including NMR, FT-IR, UV-visible, mass spectroscopy, and high pressure liquid chromatography. The results are presented of the model compound studies which strongly support the formation of a Diels-Alder adduct in the reaction of an acetylene-terminated compound and a bismaleimide or benzoquinone.

Discrete-Time Local Value Iteration Adaptive Dynamic Programming: Admissibility and Termination Analysis.

PubMed

Wei, Qinglai; Liu, Derong; Lin, Qiao

In this paper, a novel local value iteration adaptive dynamic programming (ADP) algorithm is developed to solve infinite horizon optimal control problems for discrete-time nonlinear systems. The focuses of this paper are to study admissibility properties and the termination criteria of discrete-time local value iteration ADP algorithms. In the discrete-time local value iteration ADP algorithm, the iterative value functions and the iterative control laws are both updated in a given subset of the state space in each iteration, instead of the whole state space. For the first time, admissibility properties of iterative control laws are analyzed for the local value iteration ADP algorithm. New termination criteria are established, which terminate the iterative local ADP algorithm with an admissible approximate optimal control law. Finally, simulation results are given to illustrate the performance of the developed algorithm.In this paper, a novel local value iteration adaptive dynamic programming (ADP) algorithm is developed to solve infinite horizon optimal control problems for discrete-time nonlinear systems. The focuses of this paper are to study admissibility properties and the termination criteria of discrete-time local value iteration ADP algorithms. In the discrete-time local value iteration ADP algorithm, the iterative value functions and the iterative control laws are both updated in a given subset of the state space in each iteration, instead of the whole state space. For the first time, admissibility properties of iterative control laws are analyzed for the local value iteration ADP algorithm. New termination criteria are established, which terminate the iterative local ADP algorithm with an admissible approximate optimal control law. Finally, simulation results are given to illustrate the performance of the developed algorithm.

Development and validation of a prognostic nomogram for terminally ill cancer patients.

PubMed

Feliu, Jaime; Jiménez-Gordo, Ana María; Madero, Rosario; Rodríguez-Aizcorbe, José Ramón; Espinosa, Enrique; Castro, Javier; Acedo, Jesús Domingo; Martínez, Beatriz; Alonso-Babarro, Alberto; Molina, Raquel; Cámara, Juan Carlos; García-Paredes, María Luisa; González-Barón, Manuel

2011-11-02

Determining life expectancy in terminally ill cancer patients is a difficult task. We aimed to develop and validate a nomogram to predict the length of survival in patients with terminal disease. From February 1, 2003, to December 31, 2005, 406 consecutive terminally ill patients were entered into the study. We analyzed 38 features prognostic of life expectancy among terminally ill patients by multivariable Cox regression and identified the most accurate and parsimonious model by backward variable elimination according to the Akaike information criterion. Five clinical and laboratory variables were built into a nomogram to estimate the probability of patient survival at 15, 30, and 60 days. We validated and calibrated the nomogram with an external validation cohort of 474 patients who were treated from June 1, 2006, through December 31, 2007. The median overall survival was 29.1 days for the training set and 18.3 days for the validation set. Eastern Cooperative Oncology Group performance status, lactate dehydrogenase levels, lymphocyte levels, albumin levels, and time from initial diagnosis to diagnosis of terminal disease were retained in the multivariable Cox proportional hazards model as independent prognostic factors of survival and formed the basis of the nomogram. The nomogram had high predictive performance, with a bootstrapped corrected concordance index of 0.70, and it showed good calibration. External independent validation revealed 68% predictive accuracy. We developed a highly accurate tool that uses basic clinical and analytical information to predict the probability of survival at 15, 30, and 60 days in terminally ill cancer patients. This tool can help physicians making decisions on clinical care at the end of life.

Direct observation of morphological evolution of a catalyst during carbon nanotube forest growth: new insights into growth and growth termination

NASA Astrophysics Data System (ADS)

Jeong, Seojeong; Lee, Jaegeun; Kim, Hwan-Chul; Hwang, Jun Yeon; Ku, Bon-Cheol; Zakharov, Dmitri N.; Maruyama, Benji; Stach, Eric A.; Kim, Seung Min

2016-01-01

In this study, we develop a new methodology for transmission electron microscopy (TEM) analysis that enables us to directly investigate the interface between carbon nanotube (CNT) arrays and the catalyst and support layers for CNT forest growth without any damage induced by a post-growth TEM sample preparation. Using this methodology, we perform in situ and ex situ TEM investigations on the evolution of the morphology of the catalyst particles and observe the catalyst particles to climb up through CNT arrays during CNT forest growth. We speculate that the lifted catalysts significantly affect the growth and growth termination of CNT forests along with Ostwald ripening and sub-surface diffusion. Thus, we propose a modified growth termination model which better explains various phenomena related to the growth and growth termination of CNT forests.In this study, we develop a new methodology for transmission electron microscopy (TEM) analysis that enables us to directly investigate the interface between carbon nanotube (CNT) arrays and the catalyst and support layers for CNT forest growth without any damage induced by a post-growth TEM sample preparation. Using this methodology, we perform in situ and ex situ TEM investigations on the evolution of the morphology of the catalyst particles and observe the catalyst particles to climb up through CNT arrays during CNT forest growth. We speculate that the lifted catalysts significantly affect the growth and growth termination of CNT forests along with Ostwald ripening and sub-surface diffusion. Thus, we propose a modified growth termination model which better explains various phenomena related to the growth and growth termination of CNT forests. Electronic supplementary information (ESI) available. See DOI: 10.1039/c5nr05547d

Object Localization Does Not Imply Awareness of Object Category at the Break of Continuous Flash Suppression

PubMed Central

Kobylka, Florian; Persike, Malte; Meinhardt, Günter

2017-01-01

In continuous flash suppression (CFS), a dynamic noise masker, presented to one eye, suppresses conscious perception of a test stimulus, presented to the other eye, until the suppressed stimulus comes to awareness after few seconds. But what do we see breaking the dominance of the masker in the transition period? We addressed this question with a dual-task in which observers indicated (i) whether the test object was left or right of the fixation mark (localization) and (ii) whether it was a face or a house (categorization). As done recently Stein et al. (2011a), we used two experimental varieties to rule out confounds with decisional strategy. In the terminated mode, stimulus and masker were presented for distinct durations, and the observers were asked to give both judgments at the end of the trial. In the self-paced mode, presentation lasted until the observers responded. In the self-paced mode, b-CFS durations for object categorization were about half a second longer than for object localization. In the terminated mode, correct categorization rates were consistently lower than correct detection rates, measured at five duration intervals ranging up to 2 s. In both experiments we observed an upright face advantage compared to inverted faces and houses, as concurrently reported in b-CFS studies. Our findings reveal that more time is necessary to enable observers judging the nature of the object, compared to judging that there is “something other” than the noise which can be localized, but not recognized. This suggests gradual transitions in the first break of CFS. Further, the results imply that suppression is such that no cues to object identity are conveyed in potential “leaks” of CFS (Gelbard-Sagiv et al., 2016). PMID:28663728

Evaluation of the Performance Characteristics of the CGLSS and NLDN Systems Based on Two Years of Ground-Truth Data from Launch Complex 39B, Kennedy Space Center, Florida

NASA Technical Reports Server (NTRS)

Mata, Carlos T.; Hill, Jonathan D.; Mata, Angel G.; Cummins, Kenneth L.

2014-01-01

From May 2011 through July 2013, the lightning instrumentation at Launch Complex 39B (LC39B) at the Kennedy Space Center, Florida, has obtained high-speed video records and field change waveforms (dE/dt and three-axis dH/dt) for 54 negative polarity return strokes whose strike termination locations and times are known with accuracy of the order of 10 m or less and 1 µs, respectively. A total of 18 strokes terminated directly to the LC39B lighting protection system (LPS), which contains three 181 m towers in a triangular configuration, an overhead catenary wire system on insulating masts, and nine down conductors. An additional 9 strokes terminated on the 106 m lightning protection mast of Launch Complex 39A (LC39A), which is located about 2.7 km southeast of LC39B. The remaining 27 return strokes struck either on the ground or attached to low-elevation grounded objects within about 500 m of the LC39B LPS. Leader/return stroke sequences were imaged at 3200 frames/sec by a network of six Phantom V310 high-speed video cameras. Each of the three towers on LC39B had two high-speed cameras installed at the 147 m level with overlapping fields of view of the center of the pad. The locations of the strike points of 54 return strokes have been compared to time-correlated reports of the Cloud-to-Ground Lightning Surveillance System (CGLSS) and the National Lightning Detection Network (NLDN), and the results of this comparison will be presented and discussed.

Progress toward a 30 percent-efficient, monolithic, three-junction, two-terminal concentrator solar cell for space applications

NASA Technical Reports Server (NTRS)

Partain, L. D.; Chung, B.-C.; Virshup, G. F.; Schultz, J. C.; Macmillan, H. F.; Ristow, M. Ladle; Kuryla, M. S.; Bertness, K. A.

1991-01-01

Component efficiencies of 0.2/sq cm cells at approximately 100x AMO light concentration and 80 C temperatures are not at 15.3 percent for a 1.9 eV AlGaAs top cell, 9.9 percent for a 1.4 eV GaAs middle cell under a 1.9 eV AlGaAs filter, and 2.4 percent for a bottom 1.0 eV InGaAs cell under a GaAs substrate. The goal is to continue improvement in these performance levels and to sequentially grow these devices on a single substrate to give 30 percent efficient, monolithic, two-terminal, three-junction space concentrator cells. The broad objective is a 30 percent efficient monolithic two-terminal cell that can operate under 25 to 100x AMO light concentrations and at 75 to 100 C cell temperatures. Detailed modeling predicts that this requires three junctions. Two options are being pursued, and both use a 1.9 eV AlGaAs top junction and a 1.4 eV GaAs middle junction grown by a 1 atm OMVPE on a lattice matched substrate. Option 1 uses a low-doped GaAs substrate with a lattice mismatched 1.0 eV InGaAs cell formed on the back of the substrate. Option 2 uses a Ge substrate to which the AlGaAs and GaAs top junctions are lattice matched, with a bottom 0.7 eV Ge junction formed near the substrate interface with the GaAs growth. The projected efficiency contributions are near 16, 11, and 3 percent, respectively, from the top, middle, and bottom junctions.

A Comparison Of The Universal TOR Guideline To The Absence Of Prehospital ROSC And Duration Of Resuscitation In Predicting Futility From Out-of-Hospital Cardiac Arrest

PubMed Central

Drennan, Ian R.; Case, Erin; Verbeek, P. Richard; Reynolds, Joshua C.; Goldberger, Zachary D.; Jasti, Jamie; Charleston, Mark; Herren, Heather; Idris, Ahamed H.; Leslie, Paul R.; Austin, Michael A.; Xiong, Yan; Schmicker, Robert H.; Morrison, Laurie J.

2017-01-01

Introduction The Universal Termination of Resuscitation (TOR) Guideline accurately identifies potential out-of-hospital cardiac arrest (OHCA) survivors. However, implementation is inconsistent with some emergency medical service (EMS) agencies using absence of return of spontaneous circulation (ROSC) as sole criterion for termination. Objective To compare the performance of the Universal TOR Guideline with the single criterion of no prehospital ROSC. Second, to determine factors associated with survival for patients transported without a ROSC. Lastly, to compare the impact of time to ROSC as a marker of futility to the Universal TOR Guideline. Design Retrospective, observational cohort study Participants Non-traumatic, adult (≥18 years) OHCA patients of presumed cardiac etiology treated by EMS providers Setting ROC-PRIMED and ROC-Epistry post ROC-PRIMED databases between 2007 and 2011. Outcomes Primary outcome was survival to hospital discharge and the secondary outcome was functional survival. We used multivariable regression to evaluate factors associated with survival in patients transported without a ROSC. Results 36,543 treated OHCAs occurred of which 9,467 (26%) were transported to hospital without a ROSC. Patients transported without a ROSC who met the Universal TOR Guideline for transport had a survival of 3.0% (95% CI 2.5%–3.4%) compared to 0.7% (95% CI 0.4%–0.9%) in patients who met the Universal TOR Guideline for termination. The Universal TOR Guideline identified 99% of survivors requiring continued resuscitation and transportation to hospital including early identification of survivors who sustained a ROSC after extended durations of CPR. Conclusion Using absence of ROSC as a sole predictor of futility misses potential survivors. The Universal TOR Guideline remains a strong predictor of survival. PMID:27923115

Mifepristone (RU486) in Australian pharmacies: the ethical and practical challenges.

PubMed

Lee, Rebekah Yeaun; Moles, Rebekah; Chaar, Betty

2015-01-01

The recent legalization of mifepristone has given women in Australia a new option for termination of pregnancy. Pharmacists are well positioned to provide information and supply mifepristone for patients. However, there are ethical and legal concerns in Australia regarding the supply of mifepristone, as pharmacists may choose to conscientiously object to supplying mifepristone and are subject to differing abortion laws between states and territories in Australia. The objective of this study was to explore attitudes and knowledge of Australian pharmacists about mifepristone. Semistructured interviews were conducted with 41 registered pharmacists working in a pharmacy or hospital in Sydney, Australia. When data saturation was achieved, audiotaped transcripts were deidentified and transcribed verbatim. Data were thematically analyzed using a framework approach for applied policy research and categorized into the following themes: contextual, diagnostic, evaluative and strategic. Analysis of the transcripts yielded four themes: (a) pharmacists' contextual view on pregnancy termination, the role of the pharmacist and impact on the pharmacy workplace; (b) diagnostic reasons for differing views; (c) evaluation of actual and perceived pharmacy practice in relation to the supply of mifepristone and (d) strategies to improve pharmacists' services, awareness and education. Australian pharmacists in this study perceived themselves to have a potentially important role as medicine experts in patient health care and safety in medical termination of pregnancy. However, there was a general lack of clinical, ethical and legal knowledge about medical termination of pregnancy and its legislation. To ensure patient safety, well-being and autonomy, there is an imperative need for pharmacist-specific training and guidelines to be made available and open discussion to be initiated within the profession to raise awareness, in particular regarding professional accountability for full patient care. Copyright © 2014 Elsevier Inc. All rights reserved.

MASH test 3-37 of the TxDOT 31-inch W-beam downstream anchor terminal.

DOT National Transportation Integrated Search

2011-12-01

The objective of this study was to develop a suitable replacement for the downstream turndown : guardrail anchor system. The turndown guardrail anchor system does not meet mandated test requirements : under MASH for upstream anchor applic...

Development of Reduced Sediment Volume Test Procedures for the Estuarine Amphipod Leptocheirus plumulosus

EPA Science Inventory

The sediment volume requirements of toxicity and bioaccumulation bioassays affect the cost of the assessment related to field collection, transportation, storage, disposal, and labor associated with organism recovery at bioassay termination. Our objective was to assess four redu...

Effect of leaching residual methyl methacrylate concentrations on in vitro cytotoxicity of heat polymerized denture base acrylic resin processed with different polymerization cycles

PubMed Central

BURAL, Canan; AKTAŞ, Esin; DENIZ, Günnur; ÜNLÜÇERÇI, Yeşim; BAYRAKTAR, Gülsen

2011-01-01

Objectives Residual methyl methacrylate (MMA) may leach from the acrylic resin denture bases and have adverse effects on the oral mucosa. This in vitro study evaluated and correlated the effect of the leaching residual MMA concentrations ([MMA]r) on in vitro cytotoxicity of L-929 fibroblasts. Material and Methods A total of 144 heat-polymerized acrylic resin specimens were fabricated using 4 different polymerization cycles: (1) at 74ºC for 9 h, (2) at 74ºC for 9 h and terminal boiling (at 100ºC) for 30 min, (3) at 74ºC for 9 h and terminal boiling for 3 h, (4) at 74ºC for 30 min and terminal boiling for 30 min. Specimens were eluted in a complete cell culture medium at 37ºC for 1, 2, 5 and 7 days. [MMA]r in eluates was measured using high-performance liquid chromatography. In vitro cytotoxicity of eluates on L-929 fibroblasts was evaluated by means of cell proliferation using a tetrazolium salt XTT (sodium 3´-[1-phenyl-aminocarbonyl)-3,4-tetrazolium]bis(4-methoxy-6-nitro)benzenesulphonic acid) assay. Differences in [MMA]r of eluates and cell proliferation values between polymerization cycles were statistically analyzed by Kruskal-Wallis, Friedman and Dunn's multiple comparison tests. The correlation between [MMA]r of eluates and cell proliferation was analyzed by Pearson's correlation test (p<0.05). Results [MMA]r was significantly (p≤0.001) higher in eluates of specimens polymerized with cycle without terminal boiling after elution of 1 and 2 days. Cell proliferation values for all cycles were significantly (p<0.01) lower in eluates of 1 day than those of 2 days. The correlation between [MMA]r and cell proliferation values was negative after all elution periods, showing significance (p<0.05) for elution of 1 and 2 days. MMA continued to leach from acrylic resin throughout 7 days and leaching concentrations markedly reduced after elution of 1 and 2 days. Conclusion Due to reduction of leaching residual MMA concentrations, use of terminal boiling in the polymerization process for at least 30 min and water storage of the heat-polymerized denture bases for at least 1 to 2 days before denture delivery is clinically recommended for minimizing the residual MMA and possible cytotoxic effects. PMID:21956586

76 FR 76407 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-07

... Activities; Submission to OMB for Review and Approval; Comment Request; NSPS for Bulk Gasoline Terminals... information about the electronic docket, go to http://www.regulations.gov . Title: NSPS for Bulk Gasoline... New Source Performance Standards (NSPS) for Bulk Gasoline Terminals were proposed on December 17, 1980...

Low-Cost Terminal Alternative for Learning Center Managers. Final Report.

ERIC Educational Resources Information Center

Nix, C. Jerome; And Others

This study established the feasibility of replacing high performance and relatively expensive computer terminals with less expensive ones adequate for supporting specific tasks of Advanced Instructional System (AIS) at Lowry AFB, Colorado. Surveys of user requirements and available devices were conducted and the results used in a system analysis.…

20 CFR 901.52 - Effect of suspension, termination or resignation of enrollment; surrender of enrollment certificate.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Effect of suspension, termination or resignation of enrollment; surrender of enrollment certificate. 901.52 Section 901.52 Employees' Benefits JOINT BOARD FOR THE ENROLLMENT OF ACTUARIES REGULATIONS GOVERNING THE PERFORMANCE OF ACTUARIAL SERVICES...

20 CFR 901.52 - Effect of suspension, termination or resignation of enrollment; surrender of enrollment certificate.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 4 2013-04-01 2013-04-01 false Effect of suspension, termination or resignation of enrollment; surrender of enrollment certificate. 901.52 Section 901.52 Employees' Benefits JOINT BOARD FOR THE ENROLLMENT OF ACTUARIES REGULATIONS GOVERNING THE PERFORMANCE OF ACTUARIAL SERVICES...

20 CFR 901.52 - Effect of suspension, termination or resignation of enrollment; surrender of enrollment certificate.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Effect of suspension, termination or resignation of enrollment; surrender of enrollment certificate. 901.52 Section 901.52 Employees' Benefits JOINT BOARD FOR THE ENROLLMENT OF ACTUARIES REGULATIONS GOVERNING THE PERFORMANCE OF ACTUARIAL SERVICES...

20 CFR 901.52 - Effect of suspension, termination or resignation of enrollment; surrender of enrollment certificate.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Effect of suspension, termination or resignation of enrollment; surrender of enrollment certificate. 901.52 Section 901.52 Employees' Benefits JOINT BOARD FOR THE ENROLLMENT OF ACTUARIES REGULATIONS GOVERNING THE PERFORMANCE OF ACTUARIAL SERVICES...

20 CFR 901.52 - Effect of suspension, termination or resignation of enrollment; surrender of enrollment certificate.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Effect of suspension, termination or resignation of enrollment; surrender of enrollment certificate. 901.52 Section 901.52 Employees' Benefits JOINT BOARD FOR THE ENROLLMENT OF ACTUARIES REGULATIONS GOVERNING THE PERFORMANCE OF ACTUARIAL SERVICES...

Operation mode switchable charge-trap memory based on few-layer MoS2

NASA Astrophysics Data System (ADS)

Hou, Xiang; Yan, Xiao; Liu, Chunsen; Ding, Shijin; Zhang, David Wei; Zhou, Peng

2018-03-01

Ultrathin layered two-dimensional (2D) semiconductors like MoS2 and WSe2 have received a lot of attention because of their excellent electrical properties and potential applications in electronic devices. We demonstrate a charge-trap memory with two different tunable operation modes based on a few-layer MoS2 channel and an Al2O3/HfO2/Al2O3 charge storage stack. Our device shows excellent memory properties under the traditional three-terminal operation mode. More importantly, unlike conventional charge-trap devices, this device can also realize the memory performance with just two terminals (drain and source) because of the unique atomic crystal electrical characteristics. Under the two-terminal operation mode, the erase/program current ratio can reach up to 104 with a stable retention property. Our study indicates that the conventional charge-trap memory cell can also realize the memory performance without the gate terminal based on novel two dimensional materials, which is meaningful for low power consumption and high integration density applications.

A novel adaptive finite time controller for bilateral teleoperation system

NASA Astrophysics Data System (ADS)

Wang, Ziwei; Chen, Zhang; Liang, Bin; Zhang, Bo

2018-03-01

Most bilateral teleoperation researches focus on the system stability within time-delays. However, practical teleoperation tasks require high performances besides system stability, such as convergence rate and accuracy. This paper investigates bilateral teleoperation controller design with transient performances. To ensure the transient performances and system stability simultaneously, an adaptive non-singular fast terminal mode controller is proposed to achieve practical finite-time stability considering system uncertainties and time delays. In addition, a novel switching scheme is introduced, in which way the singularity problem of conventional terminal sliding manifold is avoided. Finally, numerical simulations demonstrate the effectiveness and validity of the proposed method.

Static power reduction for midpoint-terminated busses

DOEpatents

Coteus, Paul W [Yorktown Heights, NY; Takken, Todd [Brewster, NY

2011-01-18

A memory system is disclosed which is comprised of a memory controller and addressable memory devices such as DRAMs. The invention provides a programmable register to control the high vs. low drive state of each bit of a memory system address and control bus during periods of bus inactivity. In this way, termination voltage supply current can be minimized, while permitting selected bus bits to be driven to a required state. This minimizes termination power dissipation while not affecting memory system performance. The technique can be extended to work for other high-speed busses as well.

Telerobot control system

NASA Technical Reports Server (NTRS)

Backes, Paul G. (Inventor); Tso, Kam S. (Inventor)

1993-01-01

This invention relates to an operator interface for controlling a telerobot to perform tasks in a poorly modeled environment and/or within unplanned scenarios. The telerobot control system includes a remote robot manipulator linked to an operator interface. The operator interface includes a setup terminal, simulation terminal, and execution terminal for the control of the graphics simulator and local robot actuator as well as the remote robot actuator. These terminals may be combined in a single terminal. Complex tasks are developed from sequential combinations of parameterized task primitives and recorded teleoperations, and are tested by execution on a graphics simulator and/or local robot actuator, together with adjustable time delays. The novel features of this invention include the shared and supervisory control of the remote robot manipulator via operator interface by pretested complex tasks sequences based on sequences of parameterized task primitives combined with further teleoperation and run-time binding of parameters based on task context.

GPS/REFSAT definition study report for low-cost terminals

NASA Technical Reports Server (NTRS)

1980-01-01

A relay transponder, located either on a satellite in geostationary orbit or on a local tower to relay acquisition-aiding data, ephemerides, etc, from a ground-based remote control station to a GPS civil user terminal located on a ship or land-transportation vehicle is described. Termed REFSAT (Reference Satellite), this concept reduces the circuit complexity and cost of user terminals. The various systems needed to implement the REFSAT concept for low-cost, GPS civil terminals are defined. The GPS/REFSAT system compatible with the NAVSTAR GPS system consists of a geostationary relay satellite, civil user terminals, and the central facility which performs operations common to all users for relay via the space segment. A GPS/REFSAT system utilizing a local tower for the relay transponder is described, results of a study of civil user requirements are presented, and specifications for the GPS/REFSAT system and its individual segments are included.

Actions of Acute and Chronic Ethanol on Presynaptic Terminals

PubMed Central

Roberto, Marisa; Treistman, Steven N.; Pietrzykowski, Andrzej Z.; Weiner, Jeff; Galindo, Rafael; Mameli, Manuel; Valenzuela, Fernando; Zhu, Ping Jun; Lovinger, David; Zhang, Tao A.; Hendricson, Adam H.; Morrisett, Richard; Siggins, George Robert

2014-01-01

This article presents the proceedings of a symposium entitled “The Tipsy Terminal: Presynaptic Effects of Ethanol” (held at the annual meeting of the Research Society on Alcoholism, in Santa Barbara, CA, June 27, 2005). The objective of this symposium was to focus on a cellular site of ethanol action underrepresented in the alcohol literature, but quickly becoming a “hot” topic. The chairs of the session were Marisa Roberto and George Robert Siggins. Our speakers were chosen on the basis of the diverse electrophysiological and other methods used to discern the effects of acute and chronic ethanol on presynaptic terminals and on the basis of significant insights that their data provide for understanding ethanol actions on neurons in general, as mechanisms underlying problematic behavioral effects of alcohol. The 5 presenters drew from their recent studies examining the effects of acute and chronic ethanol using a range of sophisticated methods from electrophysiological analysis of paired-pulse facilitation and spontaneous and miniature synaptic currents (Drs. Weiner, Valenzuela, Zhu, and Morrisett), to direct recording of ion channel activity and peptide release from acutely isolated synaptic terminals (Dr. Treistman), to direct microscopic observation of vesicular release (Dr. Morrisett). They showed that ethanol administration could both increase and decrease the probability of release of different transmitters from synaptic terminals. The effects of ethanol on synaptic terminals could often be correlated with important behavioral or developmental actions of alcohol. These and other novel findings suggest that future analyses of synaptic effects of ethanol should attempt to ascertain, in multiple brain regions, the role of presynaptic terminals, relevant presynaptic receptors and signal transduction linkages, exocytotic mechanisms, and their involvement in alcohol’s behavioral actions. Such studies could lead to new treatment strategies for alcohol intoxication, alcohol abuse, and alcoholism. PMID:16441271

Accelerated development of object permanence in Down's syndrome infants.

PubMed

Pasnak, C F; Pasnak, R

1987-01-01

Six infants with Down's syndrome, aged 3-19 months, were taught to solve object permanence problems. The instruction took place in the infants' homes and in a child development centre, and was conducted both by parents and by a child psychologist. Object permanence tasks ranging over stages 3-6 of the sensorimotor period of intelligence were utilized in the intervention, which lasted for up to 8 months. The infants were able to progress rather rapidly on these tasks. When the instruction was terminated most had mastered multiple visible displacements, which index the fifth stage of sensorimotor intelligence.

Congenital anomalies and termination of pregnancy in Iran.

PubMed

Samadirad, Bahram; Khamnian, Zhila; Hosseini, Mohammad Bager; Dastgiri, Saeed

2012-01-01

The aim of this study was to document some epidemiological features of termination of pregnancy for birth defects in Iran. We studied 603 pregnant women who were diagnosed/recommended for the termination of pregnancy as having a fetus with some types of birth defect(s). Most women (87.2 percent) had at least one ultrasound examination. The proportion of other screening tests including amniocentesis and genetic tests were 2.8 and 4.6 percent, respectively. Of 603 women, 201 terminated the pregnancy giving a prevalence rate of 33.3 percent (CI 95%: 29.6-37.6). The remaining 402 subjects were unable to get the permission for abortion because of untimely diagnosis/application for termination (20th week of pregnancy and/or later). Forty-eight percent of termination of pregnancies was performed before the 18th week of pregnancy. Neural tube defects, limb deformation, hydrops fetalis, hydrocephaly, and chromosomal anomalies including Down syndrome accounted proportionally for about 65 percent of defects eligible for abortion in the region. Although the rate of termination of pregnancy for birth defects is acceptable at the current situation in the country, more efforts should still be made to convince the community authorities to give more possibility and ease for the termination of pregnancy for congenital anomalies.

Assessment of accessible facilities for disabled passenger movement in aerodrome terminals in Klang Valley

NASA Astrophysics Data System (ADS)

Ramli, M. Z.; Hasnol., J. N. E.; Hamid, N. B.; Ismail, N.; Zawawi, M. H.; Zainal, M. Z.

2017-09-01

The effectiveness of accessibility in public transport has prompted a great deal of weakness and confines many disabled from moving around unreservedly. As far as the built-up environment is concerned, it is important that it should be barrier-free and adapted to fulfill the needs of all people equally. The consideration of equal accessibility to outdoor environments is still lacking. These cause the problems with poor accessibility, the disabled people face more challenges and difficulties while travelling and using the public transport. Therefore, the aim of the study is to evaluate the performance of accessible facilities for disabled movement in aerodrome terminals in Klang Valley. An assessment rating was developed from an established guideline to assess the disabled facilities provided in the Aerodrome Terminal 1 and Aerodrome Terminal 2 by using manual observation and measurement technique. Based on the results obtained, the facility for disabled people in both aerodrome terminals are moderate. Aerodrome Terminal 1 is averagely 63.46% while for Aerodrome Terminal 2 is 67.31%. Results demonstrated that effort is needed by the respective agencies and there was a demand on re-designing the current facility, so that disabled people will not face any difficulty while traveling through public transport stations or terminals.

Propagation of Sparkleberry (Vaccinium arboreum) improved via cutting type

USDA-ARS?s Scientific Manuscript database

The objectives of this study were to determine whether cutting type (softwood, semi-hardwood, or hardwood), cutting position (terminal or subterminal), IBA concentration, or the interaction of these treatments influence rooting of V. arboreum stem cuttings. Previous experiments did not specify if th...

Assessing Intermediate Outcomes of a Faith-Based Residential Prisoner Reentry Program

ERIC Educational Resources Information Center

Roman, Caterina G.; Wolff, Ashley; Correa, Vanessa; Buck, Janeen

2007-01-01

Objective: This study examined intermediate outcomes of a faith-based prisoner reentry program by assessing how client spirituality related to client- and program-level characteristics, investigating differences between completers and terminators, and examining how religious preference, religiosity/spirituality, religious salience, and…

Value and impacts of alternative fuel distribution concepts : assessing the Army's future needs for temporary fuel pipelines

DOT National Transportation Integrated Search

2009-01-01

The Army maintains the capability to employ temporary petroleum pipelines. With the fiscal year (FY) 0813 program objective memorandum (POM) force, the Army proposes to retain two Active and twelve Reserve Petroleum Pipeline and Terminal Operating...

Multi-junction Thin-film Solar Cells on Flexible Substrates for Space Power

NASA Technical Reports Server (NTRS)

Hepp, Aloysius F.; Smith, Mark; Scofield, John H.; Dickman, John E.; Lush, Gregory B.; Morel, Donald L.; Ferekides, Christos; Dhere, Neelkanth G.

2002-01-01

The ultimate objective of the thin-film program at NASA GRC is development of a 20 percent AM0 thin-film device technology with high power/weight ratio. Several approaches are outlined to improve overall device efficiency and power/weight ratio. One approach involves the use of very lightweight flexible substrates such as polyimides (i.e., Kapton(Trademark)) or metal foil. Also, a compound semiconductor tandem device structure that can meet this objective is proposed and simulated using Analysis of Microelectronic and Photonic Structures (AMPS). AMPS modeling of current devices in tandem format indicate that AM0 efficiencies near 20 percent can be achieved. And with improvements in materials, efficiencies approaching 25 percent are achievable. Several important technical issues need to be resolved to realize these complex devices: development of a wide bandgap material with good electronic properties, development of transparent contacts, and targeting a 2-terminal device structure (with more complicated processing and tunnel junction) or 4-terminal device. Recent progress in the NASA GRC program is outlined.

Effective signaling of surface boundaries by L-vertices reflect the consistency of their contrast in natural images.

PubMed

Vessel, Edward A; Biederman, Irving; Subramaniam, Suresh; Greene, Michelle R

2016-07-01

An L-vertex, the point at which two contours coterminate, provides highly reliable evidence that a surface terminates at that vertex, thus providing the strongest constraint on the extraction of shape from images (Guzman, 1968). Such vertices are pervasive in our visual world but the importance of a statistical regularity about them has been underappreciated: The contours defining the vertex are (almost) always of the same direction of contrast with respect to the background (i.e., both darker or both lighter). Here we show that when the two contours are of different directions of contrast, the capacity of the L-vertex to signal the termination of a surface, as reflected in object recognition, is markedly reduced. Although image statistics have been implicated in determining the connectivity in the earliest cortical visual stage (V1) and in grouping during visual search, this finding provides evidence that such statistics are involved in later stages where object representations are derived from two-dimensional images.

[Remote results of plastic operations on the tricuspid valve in patients with cardiac insufficiency at terminal stage].

PubMed

Habriielian, A V; Smorzhevs'kyĭ, V I; Onishchenko, V F; Beleĭovych, V V; Topchu, Ie I; Domans'kyĭ, T M; Myroniuk, O I

2011-07-01

Comparative analysis of the results of plastic operations performance on a tricuspid valve (TV) in patients, suffering cardiac insufficiency in terminal stage, was conducted. In late postoperative period the indices of intracardial hemodynamics (cardiac output fraction, regurgitation on TV) and clinical features (severity of symptoms, quality of life) after plastic operations, using a support ring, have differed significantly from those after performance of a sutured plasty. The valve function during five years was secured in 91.1% of patients.

Controls for Reusable Launch Vehicles During Terminal Area Energy Management

NASA Technical Reports Server (NTRS)

Driessen, Brian J.

2005-01-01

During the terminal energy management phase of flight (last of three phases) for a reusable launch vehicle, it is common for the controller to receive guidance commands specifying desired values for (i) the roll angle roll q(sub roll), (ii) the acceleration a(sub n) in the body negative z direction, -k(sub A)-bar, and (iii) omega(sub 3), the projection of onto the body-fixed axis k(sub A)-bar, is always indicated by guidance to be zero. The objective of the controller is to regulate the actual values of these three quantities, i.e make them close to the commanded values, while maintaining system stability.

A slewing control experiment for flexible structures

NASA Technical Reports Server (NTRS)

Juang, J.-N.; Horta, L. G.; Robertshaw, H. H.

1985-01-01

A hardware set-up has been developed to study slewing control for flexible structures including a steel beam and a solar panel. The linear optimal terminal control law is used to design active controllers which are implemented in an analog computer. The objective of this experiment is to demonstrate and verify the dynamics and optimal terminal control laws as applied to flexible structures for large angle maneuver. Actuation is provided by an electric motor while sensing is given by strain gages and angle potentiometer. Experimental measurements are compared with analytical predictions in terms of modal parameters of the system stability matrix and sufficient agreement is achieved to validate the theory.

Rail Mounted Gantry Crane Scheduling Optimization in Railway Container Terminal Based on Hybrid Handling Mode

PubMed Central

Zhu, Xiaoning

2014-01-01

Rail mounted gantry crane (RMGC) scheduling is important in reducing makespan of handling operation and improving container handling efficiency. In this paper, we present an RMGC scheduling optimization model, whose objective is to determine an optimization handling sequence in order to minimize RMGC idle load time in handling tasks. An ant colony optimization is proposed to obtain near optimal solutions. Computational experiments on a specific railway container terminal are conducted to illustrate the proposed model and solution algorithm. The results show that the proposed method is effective in reducing the idle load time of RMGC. PMID:25538768

Assessing materials handling and storage capacities in port terminals

NASA Astrophysics Data System (ADS)

Dinu, O.; Roşca, E.; Popa, M.; Roşca, M. A.; Rusca, A.

2017-08-01

Terminals constitute the factual interface between different modes and, as a result, buffer stocks are unavoidable whenever transport flows with different discontinuities meet. This is the reason why assessing materials handling and storage capacities is an important issue in the course of attempting to increase operative planning of logistic processes in terminals. Proposed paper starts with a brief review of the compatibilities between different sorts of materials and corresponding transport modes and after, a literature overview of the studies related to ports terminals and their specialization is made. As a methodology, discrete event simulation stands as a feasible technique for assessing handling and storage capacities at the terminal, taking into consideration the multi-flows interaction and the non-uniform arrivals of vessels and inland vehicles. In this context, a simulation model, that integrates the activities of an inland water terminal and describes the essential interactions between the subsystems which influence the terminal capacity, is developed. Different scenarios are simulated for diverse sorts of materials, leading to bottlenecks identification, performance indicators such as average storage occupancy rate, average dwell or transit times estimations, and their evolution is analysed in order to improve the transfer operations in the logistic process

Pancreatic stone protein (lithostathine), a physiologically relevant pancreatic calcium carbonate crystal inhibitor?

PubMed

Bimmler, D; Graf, R; Scheele, G A; Frick, T W

1997-01-31

Apart from digestive enzymes, pancreatic juice contains several proteins that are not directly involved in digestion. One of these, lithostathine, has been reported to exhibit calcite crystal inhibitor activity in vitro. As pancreatic juice is supersaturated with respect to calcium carbonate, it was hypothesized that lithostathine stabilizes pancreatic juice. Lithostathine is cleaved by trace amounts of trypsin, resulting in a C-terminal polypeptide and an N-terminal undecapeptide, which has been identified as the active site of lithostathine regarding crystal inhibition. We produced rat lithostathine in a baculovirus expression system. In order to test its functional activity, the protein was purified using a nondenaturing multi-step procedure. In the low micromolar range, recombinant rat lithostathine in vitro exhibited calcite crystal inhibitor activity, confirming earlier reports. Limited tryptic proteolysis of recombinant lithostathine was performed, and the two cleavage products were separated; the C-terminal polypeptide was precipitated by centrifugation, and the N-terminal undecapeptide was purified by high performance liquid chromatography. Only the C-terminal peptide displayed measurable calcite crystal inhibitory activity. Furthermore, synthetic undecapeptides with identical sequence to the N-terminal undecapeptides of rat or human lithostathine were inactive. However, when tested in the same in vitro assays, other pancreatic or extra-pancreatic proteins show inhibitory activity in the same concentration range as lithostathine, and inorganic phosphate is active as well. Based on these findings it seems unlikely that lithostathine is a physiologically relevant calcite crystal inhibitor. The name "lithostathine" is therefore inappropriate, and the protein's key function remains to be elucidated.

Shelter-based palliative care for the homeless terminally ill.

PubMed

Podymow, Tiina; Turnbull, Jeffrey; Coyle, Doug

2006-03-01

The homeless have high rates of mortality, but live in environments not conducive to terminal care. Traditional palliative care hospitals may be reluctant to accept such patients, due to behavior or lifestyle concerns. The Ottawa Inner City Health Project (OICHP) is a pilot study to improve health care delivery to homeless adults. This is a retrospective analysis of a cohort of terminally ill homeless individuals and the effectiveness of shelter-based palliative care. As proof of principle, a cost comparison was performed. 28 consecutive homeless terminally ill patients were admitted and died at a shelter-based palliative care hospice. Demographics, diagnoses at admission and course were recorded. Burden of illness was assessed by medical and psychiatric diagnoses, addictions, Karnofsky scale and symptom management. An expert panel was convened to identify alternate care locations. Using standard costing scales, direct versus alternate care costs were compared. 28 patients had a mean age 49 years; average length of stay 120 days. DIAGNOSES: liver disease 43%, HIV/AIDS 25%, malignancy 25% and other 8%. Addiction to drugs or alcohol and mental illness in 82% of patients. Karnofsky performance score mean 40 +/- 16.8. Pain management with continuous opiates in 71%. The majority reunited with family. Compared to alternate care locations, the hospice projected 1.39 million dollars savings for the patients described. The homeless terminally ill have a heavy burden of disease including physical illness, psychiatric conditions and addictions. Shelter-based palliative care can provide effective end-of-life care to terminally ill homeless individuals at potentially substantial cost savings.

49 CFR 23.39 - What other certification requirements apply in the case of ACDBEs?

Code of Federal Regulations, 2010 CFR

2010-10-01

... the firm and its key personnel to perform the concession contracts or other contracts it wishes to... private terminal owners or lessees are not authorized to certify firms as ACDBEs. As a car rental company or private terminal owner or lessee, you must obtain ACDBE participation from firms which a recipient...

49 CFR 23.39 - What other certification requirements apply in the case of ACDBEs?

Code of Federal Regulations, 2012 CFR

2012-10-01

... the firm and its key personnel to perform the concession contracts or other contracts it wishes to... private terminal owners or lessees are not authorized to certify firms as ACDBEs. As a car rental company or private terminal owner or lessee, you must obtain ACDBE participation from firms which a recipient...

49 CFR 23.39 - What other certification requirements apply in the case of ACDBEs?

Code of Federal Regulations, 2011 CFR

2011-10-01

... the firm and its key personnel to perform the concession contracts or other contracts it wishes to... private terminal owners or lessees are not authorized to certify firms as ACDBEs. As a car rental company or private terminal owner or lessee, you must obtain ACDBE participation from firms which a recipient...

49 CFR 23.39 - What other certification requirements apply in the case of ACDBEs?

Code of Federal Regulations, 2013 CFR

2013-10-01

... the firm and its key personnel to perform the concession contracts or other contracts it wishes to... private terminal owners or lessees are not authorized to certify firms as ACDBEs. As a car rental company or private terminal owner or lessee, you must obtain ACDBE participation from firms which a recipient...

49 CFR 23.39 - What other certification requirements apply in the case of ACDBEs?

Code of Federal Regulations, 2014 CFR

2014-10-01

... the firm and its key personnel to perform the concession contracts or other contracts it wishes to... private terminal owners or lessees are not authorized to certify firms as ACDBEs. As a car rental company or private terminal owner or lessee, you must obtain ACDBE participation from firms which a recipient...

"The End Could Be Just the Beginning": The Study of Relationship Termination through the Performance of Literature.

ERIC Educational Resources Information Center

West, Richard L.; Gentile, John S.

Noting that breaking off romantic relationships can be traumatic even when the end is welcome, this paper describes the strategies and stages of relationship termination and suggests ways for instructors of oral interpretation and/or interpersonal communication classes to illustrate such relational decay. The first section deals with relationship…

7 CFR 1494.801 - Enforcement and termination of agreements with CCC.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Enforcement and termination of agreements with CCC... CCC. (a) Performance in accordance with an Agreement with CCC. (1) An exporter which enters into an Agreement with CCC must ensure that the eligible commodity is exported from the U.S. and enters the eligible...

Influence of native catfish mucus on Flavobacterium columnare growth and proteolytic activity

USDA-ARS?s Scientific Manuscript database

Flavobacterium columnare causes columnaris disease of farmed and wild freshwater fish. Skin mucus is an important factor in early stages of columnaris pathogenesis, albeit little studied. Our objectives were to 1) characterize the terminal glycosylation pattern (TGP) of catfish mucus, 2) determine t...

A Vision-Based Motion Sensor for Undergraduate Laboratories.

ERIC Educational Resources Information Center

Salumbides, Edcel John; Maristela, Joyce; Uy, Alfredson; Karremans, Kees

2002-01-01

Introduces an alternative method to determine the mechanics of a moving object that uses computer vision algorithms with a charge-coupled device (CCD) camera as a recording device. Presents two experiments, pendulum motion and terminal velocity, to compare results of the alternative and conventional methods. (YDS)

Determine the Requirements for Existing Pipeline, Tank and Terminal Systems to Transport Ethanol without Cracking

DOT National Transportation Integrated Search

2010-06-18

The potential exists for stress corrosion cracking (SCC) of carbon steel pipelines transporting fuel grade ethanol (FGE) and FGE- gasoline blends. The objectives of SCC 4-4 were to: 1. Develop data necessary to make engineering assessments of the fea...

A Terminal Pharmaceutics Course in Clinical Pharmacokinetics.

ERIC Educational Resources Information Center

Reuning, Richard H.; Krautheim, Daniel

1978-01-01

At Ohio State University, an undergraduate course extends the course sequence in biopharmaceutics and pharmacokinetics to application to problems in optimizing drug therapy. Course content, structure, instructional methods, and student term projects are described, and a course outline, typical projects, and some behavioral objectives are appended.…

Research Analysis on MOOC Course Dropout and Retention Rates

ERIC Educational Resources Information Center

Gomez-Zermeno, Marcela Gerogina; Aleman de La Garza, Lorena

2016-01-01

This research's objective was to identify the terminal efficiency of the Massive Online Open Course "Educational Innovation with Open Resources" offered by a Mexican private university. A quantitative methodology was used, combining descriptive statistics and probabilistic models to analyze the levels of retention, completion, and…

Formulating New Directions with Strategic Marketing Planning.

ERIC Educational Resources Information Center

Crompton, John L.

1983-01-01

This article describes both a short- and long-term strategic marketing planning approach for the parks and recreation manager. Both plans involve a needs assessment, objective development, marketing plans, and evaluations. Also discussed is a continuum of stragetic program options ranging from developing new programs to terminating existing…

Saccade-related activity in the prefrontal cortex: its role in eye movement control and cognitive functions

PubMed Central

Funahashi, Shintaro

2014-01-01

Prefrontal neurons exhibit saccade-related activity and pre-saccadic memory-related activity often encodes the directions of forthcoming eye movements, in line with demonstrated prefrontal contribution to flexible control of voluntary eye movements. However, many prefrontal neurons exhibit post-saccadic activity that is initiated well after the initiation of eye movement. Although post-saccadic activity has been observed in the frontal eye field, this activity is thought to be a corollary discharge from oculomotor centers, because this activity shows no directional tuning and is observed whenever the monkeys perform eye movements regardless of goal-directed or not. However, prefrontal post-saccadic activities exhibit directional tunings similar as pre-saccadic activities and show context dependency, such that post-saccadic activity is observed only when monkeys perform goal-directed saccades. Context-dependency of prefrontal post-saccadic activity suggests that this activity is not a result of corollary signals from oculomotor centers, but contributes to other functions of the prefrontal cortex. One function might be the termination of memory-related activity after a behavioral response is done. This is supported by the observation that the termination of memory-related activity coincides with the initiation of post-saccadic activity in population analyses of prefrontal activities. The termination of memory-related activity at the end of the trial ensures that the subjects can prepare to receive new and updated information. Another function might be the monitoring of behavioral performance, since the termination of memory-related activity by post-saccadic activity could be associated with informing the correctness of the response and the termination of the trial. However, further studies are needed to examine the characteristics of saccade-related activities in the prefrontal cortex and their functions in eye movement control and a variety of cognitive functions. PMID:25071482

Real-time acquisition and tracking system with multiple Kalman filters

NASA Astrophysics Data System (ADS)

Beard, Gary C.; McCarter, Timothy G.; Spodeck, Walter; Fletcher, James E.

1994-07-01

The design of a real-time, ground-based, infrared tracking system with proven field success in tracking boost vehicles through burnout is presented with emphasis on the software design. The system was originally developed to deliver relative angular positions during boost, and thrust termination time to a sensor fusion station in real-time. Autonomous target acquisition and angle-only tracking features were developed to ensure success under stressing conditions. A unique feature of the system is the incorporation of multiple copies of a Kalman filter tracking algorithm running in parallel in order to minimize run-time. The system is capable of updating the state vector for an object at measurement rates approaching 90 Hz. This paper will address the top-level software design, details of the algorithms employed, system performance history in the field, and possible future upgrades.

Defrost Temperature Termination in Supermarket Refrigeration Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fricke, Brian A; Sharma, Vishaldeep

2011-11-01

The objective of this project was to determine the potential energy savings associated with implementing demand defrost strategies to defrost supermarket refrigerated display case evaporators, as compared to the widely accepted current practice of controlling display case defrost cycles with a preset timer. The defrost heater energy use of several representative display case types was evaluated. In addition, demand defrost strategies for refrigerated display cases as well as those used in residential refrigerator/freezers were evaluated. Furthermore, it is anticipated that future work will include identifying a preferred defrost strategy, with input from Retail Energy Alliance members. Based on this strategy,more » a demand defrost system will be designed which is suitable for supermarket refrigerated display cases. Limited field testing of the preferred defrost strategy will be performed in a supermarket environment.« less

Designing with non-linear viscoelastic fluids

NASA Astrophysics Data System (ADS)

Schuh, Jonathon; Lee, Yong Hoon; Allison, James; Ewoldt, Randy

2017-11-01

Material design is typically limited to hard materials or simple fluids; however, design with more complex materials can provide ways to enhance performance. Using the Criminale-Ericksen-Filbey (CEF) constitutive model in the thin film lubrication limit, we derive a modified Reynolds Equation (based on asymptotic analysis) that includes shear thinning, first normal stress, and terminal regime viscoelastic effects. This allows for designing non-linear viscoelastic fluids in thin-film creeping flow scenarios, i.e. optimizing the shape of rheological material properties to achieve different design objectives. We solve the modified Reynolds equation using the pseudo-spectral method, and describe a case study in full-film lubricated sliding where optimal fluid properties are identified. These material-agnostic property targets can then guide formulation of complex fluids which may use polymeric, colloidal, or other creative approaches to achieve the desired non-Newtonian properties.

Reusable Reentry Satellite (RRS): Recovery tradeoff study

NASA Technical Reports Server (NTRS)

1990-01-01

The main objectives of the Recovery Tradeoff Study were as follows: (1) to determine whether a land or water recovery best suits RRS system requirements; (2) what type of terminal recovery system is best suited for the RRS; and (3) what are the recovery access timelines after system landing. Based on the trade parameters and evaluation criteria used in this study, the land-landing configuration has an advantage over the water-landing configuration. It is recommended that a land-landing configuration be developed assuming WSMR as the landing site. It is also recommended that natural orbits be used for low inclination missions and any orbit adjustments for landing site targeting be performed at the end of the mission. Near-integer orbits should be used for high inclination missions and allow orbital decay to precess the ground track over the landing site range.

Degradation pattern of photosystem II reaction center protein D1 in intact leaves. The major photoinhibition-induced cleavage site in D1 polypeptide is located amino terminally of the DE loop.

PubMed

Kettunen, R; Tyystjärvi, E; Aro, E M

1996-08-01

Photoinhibition-induced degradation of the D1 protein of the photosystem II reaction center was studied in intact pumpkin (Cucurbita pepo L.) leaves. Photoinhibition was observed to cause the cleavage of the D1 protein at two distinct sites. The main cleavage generated an 18-kD N-terminal and a 20-kD C-terminal degradation fragment of the D1 protein. this cleavage site was mapped to be located clearly N terminally of the DE loop. The other, less-frequent cleavage occurred at the DE loop and produced the well-documented 23-kD, N-terminal D1 degradation product. Furthermore, the 23-kD, N-terminal D1 fragment appears to be phosphorylated and can be detected only under severe photoinhibition in vivo. Comparison of the D1 degradation pattern after in vivo photoinhibition to that after in vitro acceptor-side and donor-side photoinhibition, performed with isolated photosystem II core particles, gives indirect evidence in support of donor-side photoinhibition in intact leaves.

Terminal sedation and euthanasia: a comparison of clinical practices.

PubMed

Rietjens, Judith A C; van Delden, Johannes J M; van der Heide, Agnes; Vrakking, Astrid M; Onwuteaka-Philipsen, Bregje D; van der Maas, Paul J; van der Wal, Gerrit

2006-04-10

An important issue in the debate about terminal sedation is the extent to which it differs from euthanasia. We studied clinical differences and similarities between both practices in the Netherlands. Personal interviews were held with a nationwide stratified sample of 410 physicians (response rate, 85%) about the most recent cases in which they used terminal sedation, defined as administering drugs to keep the patient continuously in deep sedation or coma until death without giving artificial nutrition or hydration (n = 211), or performed euthanasia, defined as administering a lethal drug at the request of a patient with the explicit intention to hasten death (n = 123). We compared characteristics of the patients, the decision-making process, and medical care of both practices. Terminal sedation and euthanasia both mostly concerned patients with cancer. Patients receiving terminal sedation were more often anxious (37%) and confused (24%) than patients receiving euthanasia (15% and 2%, respectively). Euthanasia requests were typically related to loss of dignity and a sense of suffering without improving, whereas requesting terminal sedation was more often related to severe pain. Physicians applying terminal sedation estimated that the patient's life had been shortened by more than 1 week in 27% of cases, compared with 73% in euthanasia cases. Terminal sedation and euthanasia both are often applied to address severe suffering in terminally ill patients. However, terminal sedation is typically used to address severe physical and psychological suffering in dying patients, whereas perceived loss of dignity during the last phase of life is a major problem for patients requesting euthanasia.

Impact of a quality improvement project on deceased organ donor management

PubMed Central

Olmos, Andrea; Feiner, John; Hirose, Ryutaro; Swain, Sharon; Blasi, Annabel; Roberts, John P.; Niemann, Claus U.

2017-01-01

Context Donors showed poor glucose control in the period between declaration of brain death and organ recovery. The level of hyperglycemia in the donors was associated with a decline in terminal renal function. Objective To determine whether implementation of a quality improvement project improved glucose control and preserved renal function in deceased organ donors. Methods Data collected retrospectively included demographics, medical history, mechanism of death, laboratory values, and data from the United Network for Organ Sharing. Results After implementation of the quality improvement project, deceased donors had significantly lower mean glucose concentrations (mean [SD], 162 [44] vs 212 [42] mg/dL; P < .001) and prerecovery glucose concentration (143 [66] vs 241 [69] mg/dL; P < .001). When the donor cohorts from before and after the quality improvement project were analyzed together, mean glucose concentration remained a significant predictor of terminal creatinine level (P < .001). Multivariate analysis of delayed graft function in kidney recipients matched to donors indicated that higher terminal creatinine level was associated with delayed graft function in recipients (P < .001). Conclusion The quality improvement project improved donor glucose homeostasis, and the data confirm that poor glucose homeostasis is associated with worsening terminal renal function. PMID:26645930

An efficient and accurate solution methodology for bilevel multi-objective programming problems using a hybrid evolutionary-local-search algorithm.

PubMed

Deb, Kalyanmoy; Sinha, Ankur

2010-01-01

Bilevel optimization problems involve two optimization tasks (upper and lower level), in which every feasible upper level solution must correspond to an optimal solution to a lower level optimization problem. These problems commonly appear in many practical problem solving tasks including optimal control, process optimization, game-playing strategy developments, transportation problems, and others. However, they are commonly converted into a single level optimization problem by using an approximate solution procedure to replace the lower level optimization task. Although there exist a number of theoretical, numerical, and evolutionary optimization studies involving single-objective bilevel programming problems, not many studies look at the context of multiple conflicting objectives in each level of a bilevel programming problem. In this paper, we address certain intricate issues related to solving multi-objective bilevel programming problems, present challenging test problems, and propose a viable and hybrid evolutionary-cum-local-search based algorithm as a solution methodology. The hybrid approach performs better than a number of existing methodologies and scales well up to 40-variable difficult test problems used in this study. The population sizing and termination criteria are made self-adaptive, so that no additional parameters need to be supplied by the user. The study indicates a clear niche of evolutionary algorithms in solving such difficult problems of practical importance compared to their usual solution by a computationally expensive nested procedure. The study opens up many issues related to multi-objective bilevel programming and hopefully this study will motivate EMO and other researchers to pay more attention to this important and difficult problem solving activity.

Terminal illness and the increased mortality risk of conventional antipsychotics in observational studies: a systematic review.

PubMed

Luijendijk, Hendrika J; de Bruin, Niels C; Hulshof, Tessa A; Koolman, Xander

2016-02-01

Numerous large observational studies have shown an increased risk of mortality in elderly users of conventional antipsychotics. Health authorities have warned against use of these drugs. However, terminal illness is a potentially strong confounder of the observational findings. So, the objective of this study was to systematically assess whether terminal illness may have biased the observational association between conventional antipsychotics and risk of mortality in elderly patients. Studies were searched in PubMed, CINAHL, Embase, the references of selected studies and articles referring to selected studies (Web of Science). Inclusion criteria were (i) observational studies that estimated (ii) the risk of all-cause mortality in (iii) new elderly users of (iv) conventional antipsychotics compared with atypical antipsychotics or no use. Two investigators assessed the characteristics of the exposure and reference groups, main results, measured confounders and methods used to adjust for unmeasured confounders. We identified 21 studies. All studies were based on administrative medical and pharmaceutical databases. Sicker and older patients received conventional antipsychotics more often than new antipsychotics. The risk of dying was especially high in the first month of use, and when haloperidol was administered per injection or in high doses. Terminal illness was not measured in any study. Instrumental variables that were used were also confounded by terminal illness. We conclude that terminal illness has not been adjusted for in observational studies that reported an increased risk of mortality risk in elderly users of conventional antipsychotics. As the validity of the evidence is questionable, so is the warning based on it. Copyright © 2015 John Wiley & Sons, Ltd.

Analysis of a terminal landing on Mars

NASA Astrophysics Data System (ADS)

Tuckness, Dan G.

1995-01-01

This study consists of a preliminary performance and sensitivity assessment of trajectory and guidance capabilities of a Mars terminal landing phase. The phase begins with the end of the entry phase, which is at parachute deployment. Therefore, the trajectory investigated in this study starts at parachute deployment and continues through parachute jettison and finally propulsive deceleration and maneuvering to a specified landing site. Various landing navigation maneuver schemes and environmental conditions for the lander are investigated and their performance analyzed. Effects of atmospheric density and surface wind deviations on landing guidance are investigated using stochastic wind and density models. Simulation shows that the lander guidance is robust to wind and density dispersions. Density dispersions are found to be more critical for a precision landing than wind dispersions. Also, because of the aerodynamic characteristics of current aeroshell vehicle designs, very little terminal maneuvering is allowed for navigation.

Cure Chemistry of Phenylethynyl Terminated Oligomers

NASA Technical Reports Server (NTRS)

Wood, Karen H.; Orwoll, Robert A.; Young, Philip R.; Jensen, Brian J.; McNair, Harold M.

1997-01-01

The ability to process high performance polymers into quality, void-free composites has been significantly advanced using oligomers terminated with reactive groups which cure or crosslink at elevated temperature without the evolution of volatile byproducts. Several matrix resin systems of considerable interest to the aerospace community utilize phenylethynyl-terminated imide (PETI) technology to achieve this advantage. The present paper addresses the cure chemistry of PETI oligomers. The thermal cure of a low molecular weight model compound was studied using a variety of analytical techniques including differential scanning calorimetry, Fourier transform infrared spectroscopy, and liquid chromatography-mass spectroscopy. The studies indicate an extremely complex cure process. Many stable products were isolated and this paper reports current work on identification of those products. The intent of this research is to provide fundamental insight into the molecular structure of the cured PETI engineering materials so that performance and durability can be more fully assessed.

Location-allocation models and new solution methodologies in telecommunication networks

NASA Astrophysics Data System (ADS)

Dinu, S.; Ciucur, V.

2016-08-01

When designing a telecommunications network topology, three types of interdependent decisions are combined: location, allocation and routing, which are expressed by the following design considerations: how many interconnection devices - consolidation points/concentrators should be used and where should they be located; how to allocate terminal nodes to concentrators; how should the voice, video or data traffic be routed and what transmission links (capacitated or not) should be built into the network. Including these three components of the decision into a single model generates a problem whose complexity makes it difficult to solve. A first method to address the overall problem is the sequential one, whereby the first step deals with the location-allocation problem and based on this solution the subsequent sub-problem (routing the network traffic) shall be solved. The issue of location and allocation in a telecommunications network, called "The capacitated concentrator location- allocation - CCLA problem" is based on one of the general location models on a network in which clients/demand nodes are the terminals and facilities are the concentrators. Like in a location model, each client node has a demand traffic, which must be served, and the facilities can serve these demands within their capacity limit. In this study, the CCLA problem is modeled as a single-source capacitated location-allocation model whose optimization objective is to determine the minimum network cost consisting of fixed costs for establishing the locations of concentrators, costs for operating concentrators and costs for allocating terminals to concentrators. The problem is known as a difficult combinatorial optimization problem for which powerful algorithms are required. Our approach proposes a Fuzzy Genetic Algorithm combined with a local search procedure to calculate the optimal values of the location and allocation variables. To confirm the efficiency of the proposed algorithm with respect to the quality of solutions, significant size test problems were considered: up to 100 terminal nodes and 50 concentrators on a 100 × 100 square grid. The performance of this hybrid intelligent algorithm was evaluated by measuring the quality of its solutions with respect to the following statistics: the standard deviation and the ratio of the best solution obtained.

Solar Terminator Waves in the Ionosphere Measured by the Wallops Island, VA Dynasonde

NASA Astrophysics Data System (ADS)

Zabotin, N. A.; Song, H.; Bullett, T. W.

2017-12-01

Solar terminator represents a unique source of atmospheric waves possessing of near-ideal coherent properties: its geometry and magnitude of the impact changes very little from day to day. This feature has been used in [Forbes et al., GRL, 2008] to obtain "snapshots" of terminator waves in the neutral atmosphere at the altitude 400 km by averaging CHAMP accelerometer data over relatively long sequences of the satellite passes. The results were represented in the geographic latitude vs local time coordinates. We apply a similar approach averaging time series of Wallops Island, VA Dynasonde Doppler data to obtain "snapshots" of terminator waves in the ionosphere in the true altitude vs local "terminator time" coordinates. The averaging is performed independently for every month of the yearlong observation period from May 2013 to April 2014. The altitude range covered is 90 km to 400 km with 2 km resolution, representing the entire bottom-side ionosphere. Individual local time segments used for the averaging were 12 hours long and all centered at the times of the sunrise or sunset terminator passing at every specific altitude. This procedure effectively suppresses all kinds of incoherent wave activity and allows one to reveal the perturbation phenomenon mainly caused by the solar terminator. This is an important advantage of this technique compared to multiple "terminator wave" studies based on simple time coincidence. Both sunrise and sunset terminator waves are easily visualized in all of the monthly images. Our results confirm observations of [Forbes et al., GRL, 2008] of the wave structures existing on both sides of the terminator. The phase fronts of the sunset terminator wave are propagating downward indicating upward movement of the terminator-related disturbance and of the wave energy generated by it. The phase fronts of the sunrise terminator waves are propagating upward indicating downward movement of the terminator-related disturbance and of the wave energy generated by it. Spectral analysis of the local time sequences reveals characteristic peaks in the terminator-related wave activity corresponding to the periods 40-60 min and 2 hours. We also analyze statistics of their horizontal wavelengths.

Terminal shock position and restart control of a Mach 2.7, two-dimensional, twin duct mixed compression inlet

NASA Technical Reports Server (NTRS)

Cole, G. L.; Neiner, G. H.; Baumbick, R. J.

1973-01-01

Experimental results of terminal shock and restart control system tests of a two-dimensional, twin-duct mixed compression inlet are presented. High-response (110-Hz bandwidth) overboard bypass doors were used, both as the variable to control shock position and as the means of disturbing the inlet airflow. An inherent instability in inlet shock position resulted in noisy feedback signals and thus restricted the terminal shock position control performance that was achieved. Proportional-plus-integral type controllers using either throat exit static pressure or shock position sensor feedback gave adequate low-frequency control. The inlet restart control system kept the terminal shock control loop closed throughout the unstart-restart transient. The capability to restart the inlet was non limited by the inlet instability.

36 CFR 14.25 - Documents which must accompany application.

Code of Federal Regulations, 2010 CFR

2010-07-01

... terminal points of the survey should be accurately connected by course and distance to the nearest corner... connection will be made to some prominent natural object or permanent monument, which can be readily... the witness monuments and the connecting courses and distances to the original corners should be shown...

Frog egg growth, experiment S003

NASA Technical Reports Server (NTRS)

Young, R. S.; Tremor, J. W.

1971-01-01

The objective of experiment was to determine the effect of weightlessness on the ability of a fertilized frog egg to divide normally and to differentiate and form a normal embryo. This experiment was first attempted on the Gemini 8 mission and was completed only partially because of the early termination of that mission.

Terminal Velocity of a Shuttlecock in Vertical Fall.

ERIC Educational Resources Information Center

Peastrel, Mark; And Others

1980-01-01

Describes a straightforward vertical fall experiment using a badminton shuttlecock, a tape measure, and a millisecond timer. The effects of air resistance are important and directly measurable. The experimental data best fit a predictive model which assumes a resistive force quadratic in the instantaneous speed of the falling object. (GS)

Trade Education Syllabus in Graphics Industries Occupations.

ERIC Educational Resources Information Center

New York State Education Dept., Albany. Bureau of Occupational Education Curriculum Development.

This syllabus provides occupational education teachers in secondary schools with a guide for developing a course in trade graphics which meets the minimal requirements that an acceptable two-year program in New York State must provide. The content is presented in six sections, and each one includes terminal objectives and suggestions for…

"Let There Be Light" Minicourse, Career Oriented Pre-Technical Physics.

ERIC Educational Resources Information Center

Dallas Independent School District, TX.

This instructional guide, intended for student use, develops the concept of light through a series of sequential activities. A technical development of the subject is pursued with examples stressing practical aspects of the concepts. Included in the minicourse are: (1) the rationale, (2) terminal behavioral objectives, (3) enabling behavioral…

Agriculture Education. Soybeans and Rice.

ERIC Educational Resources Information Center

Stuttgart Public Schools, AR.

This curriculum guide is designed for group instruction of secondary students enrolled in one or two semester-long courses in agricultural education. The guide presents units of study in the following areas: (1) soybeans, (2) rice, and (3) orientation. Each of the 17 units of instruction follows a typical format: terminal objective, specific…

Radioactivity and Man Minicourse, Career Oriented Pre-Technical Physics.

ERIC Educational Resources Information Center

Dallas Independent School District, TX.

This instructional guide, intended for student use, develops the subject of radioactivity and man through a series of sequential activities. A technical development of the subject is pursued with examples stressing practical aspects of the concepts. Included in the minicourse are: (1) the rationale, (2) terminal behavioral objectives, (3) enabling…

Matching Older Workers to Jobs: The Industrial Health Counseling Service.

ERIC Educational Resources Information Center

Ossofsky, Eula W.

1986-01-01

GULHEMP, an occupational health system used by the Industrial Health Counseling Service (IHCS) in Portland, Maine, improves the match between middle-aged and older workers' abilities and the demands of specific jobs. It provides objective criteria upon which to base decisions to hire, promote, transfer, or terminate workers. (JOW)

New York Power Authority Pouch Terminal Power Plant, Staten Island, NY; Petition to Object to Title V Operating Permit

EPA Pesticide Factsheets

This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database.

Intergroup Relations Curriculum. Program Report.

ERIC Educational Resources Information Center

Bye, Margaret

The description provides information on the elementary social studies one-year program designed for use as the basis of curriculum or as a supplement to an existing program. A long term goal is for students to develop democratic human relations. Terminal objectives include affective and cognitive developments, helping students to understand the…

Sedimentation Solutions for Military Ocean Terminal Sunny Point (MOTSU), North Carolina

DTIC Science & Technology

2012-07-01

quality at MOTSU at the request of US Army Engineer District–Wilmington (USAED-SAW). The objective was achieved through numerical modeling ...literature review, and sediment forecasting. This report documents the results of the numerical modeling study only. Two advantageous approaches for...data .............................................................................................................. 25  4  Model Development

Report on the Total System Computer Program for Medical Libraries.

ERIC Educational Resources Information Center

Divett, Robert T.; Jones, W. Wayne

The objective of this project was to develop an integrated computer program for the total operations of a medical library including acquisitions, cataloging, circulation, reference, a computer catalog, serials controls, and current awareness services. The report describes two systems approaches: the batch system and the terminal system. The batch…

The Soviet Objective of War Termination: Limits and Constraints

DTIC Science & Technology

1988-06-01

results, even the best, must be regarded as a base, as a trampoline , for achieving still higher indicators. What is considered a success today may no...organizations. According to Boris Ponomarev, former head of the Soviet’s International Department, such contacts would establish "broad alliances covering the

An economic assessment of STOL aircraft potential including terminal area environmental considerations. Volume 2: Appendices

NASA Technical Reports Server (NTRS)

Solomon, H. L.; Sokolsky, S.

1973-01-01

An economic assessment of short takeoff aircraft for short haul air transportation applications is presented. The economic viability and environmental compatibility of short takeoff aircraft service in high density areas were evaluated. The subjects discussed are: (1) aircraft configurations and performance, (2) airfield and terminal requirements, and (3) direct and indirect operating costs.

Buck-boost converter for simultaneous semi-active vibration control and energy harvesting for electromagnetic regenerative shock absorber

NASA Astrophysics Data System (ADS)

Li, Peng; Zhang, Chongxiao; Kim, Junyoung; Yu, Liangyao; Zuo, Lei

2014-04-01

Regenerative semi-active suspensions can capture the previously dissipated vibration energy and convert it to usable electrical energy for powering on-board electronic devices, while achieve both the better ride comfort and improved road handling performance at the same time when certain control is applied. To achieve this objective, the power electronics interface circuit connecting the energy harvester and the electrical loads, which can perform simultaneous vibration control and energy harvesting function is in need. This paper utilized a buck-boost converter for simultaneous semi-active vibration control and energy harvesting with electromagnetic regenerative shock absorber, which utilizes a rotational generator to converter the vibration energy to electricity. It has been found that when the circuit works in discontinuous current mode (DCM), the ratio between the input voltage and current is only related to the duty cycle of the switch pulse width modulation signal. Using this property, the buck-boost converter can be used to perform semi-active vibration control by controlling the load connected between the terminals of the generator in the electromagnetic shock absorber. While performing the vibration control, the circuit always draw current from the shock absorber and the suspension remain dissipative, and the shock absorber takes no additional energy to perform the vibration control. The working principle and dynamics of the circuit has been analyzed and simulations were performed to validate the concept.

Test Report for NASA MSFC Support of the Linear Aerospike SR-71 Experiment (LASRE)

NASA Technical Reports Server (NTRS)

Elam, S. K.

2000-01-01

The Linear Aerospike SR-71 Experiment (LASRE) was performed in support of the Reusable Launch Vehicle (RLV) program to help develop a linear aerospike engine. The objective of this program was to operate a small aerospike engine at various speeds and altitudes to determine how slipstreams affect the engine's performance. The joint program between government and industry included NASA!s Dryden Flight Research Center, The Air Force's Phillips Laboratory, NASA's Marshall Space Flight Center, Lockheed Martin Skunkworks, Lockheed-Martin Astronautics, and Rocketdyne Division of Boeing North American. Ground testing of the LASRE engine produced two successful hot-fire tests, along with numerous cold flows to verify sequencing and operation before mounting the assembly on the SR-71. Once installed on the aircraft, flight testing performed several cold flows on the engine system at altitudes ranging from 30,000 to 50,000 feet and Mach numbers ranging from 0.9 to 1.5. The program was terminated before conducting hot-fires in flight because excessive leaks in the propellant supply systems could not be fixed to meet required safety levels without significant program cost and schedule impacts.

Research on quality metrics of wireless adaptive video streaming

NASA Astrophysics Data System (ADS)

Li, Xuefei

2018-04-01

With the development of wireless networks and intelligent terminals, video traffic has increased dramatically. Adaptive video streaming has become one of the most promising video transmission technologies. For this type of service, a good QoS (Quality of Service) of wireless network does not always guarantee that all customers have good experience. Thus, new quality metrics have been widely studies recently. Taking this into account, the objective of this paper is to investigate the quality metrics of wireless adaptive video streaming. In this paper, a wireless video streaming simulation platform with DASH mechanism and multi-rate video generator is established. Based on this platform, PSNR model, SSIM model and Quality Level model are implemented. Quality Level Model considers the QoE (Quality of Experience) factors such as image quality, stalling and switching frequency while PSNR Model and SSIM Model mainly consider the quality of the video. To evaluate the performance of these QoE models, three performance metrics (SROCC, PLCC and RMSE) which are used to make a comparison of subjective and predicted MOS (Mean Opinion Score) are calculated. From these performance metrics, the monotonicity, linearity and accuracy of these quality metrics can be observed.

The Effects of Renal Denervation on Renal Hemodynamics and Renal Vasculature in a Porcine Model

PubMed Central

Verloop, Willemien L.; Hubens, Lisette E. G.; Spiering, Wilko; Doevendans, Pieter A.; Goldschmeding, Roel; Bleys, Ronald L. A. W.; Voskuil, Michiel

2015-01-01

Rationale Recently, the efficacy of renal denervation (RDN) has been debated. It is discussed whether RDN is able to adequately target the renal nerves. Objective We aimed to investigate how effective RDN was by means of functional hemodynamic measurements and nerve damage on histology. Methods and Results We performed hemodynamic measurements in both renal arteries of healthy pigs using a Doppler flow and pressure wire. Subsequently unilateral denervation was performed, followed by repeated bilateral hemodynamic measurements. Pigs were terminated directly after RDN or were followed for 3 weeks or 3 months after the procedure. After termination, both treated and control arteries were prepared for histology to evaluate vascular damage and nerve damage. Directly after RDN, resting renal blood flow tended to increase by 29±67% (P = 0.01). In contrast, renal resistance reserve increased from 1.74 (1.28) to 1.88 (1.17) (P = 0.02) during follow-up. Vascular histopathology showed that most nerves around the treated arteries were located outside the lesion areas (8±7 out of 55±25 (14%) nerves per pig were observed within a lesion area). Subsequently, a correlation was noted between a more impaired adventitia and a reduction in renal resistance reserve (β: -0.33; P = 0.05) at three weeks of follow-up. Conclusion Only a small minority of renal nerves was targeted after RDN. Furthermore, more severe adventitial damage was related to a reduction in renal resistance in the treated arteries at follow-up. These hemodynamic and histological observations may indicate that RDN did not sufficiently target the renal nerves. Potentially, this may explain the significant spread in the response after RDN. PMID:26587981

Two Algorithms for High-throughput and Multi-parametric Quantification of Drosophila Neuromuscular Junction Morphology.

PubMed

Castells-Nobau, Anna; Nijhof, Bonnie; Eidhof, Ilse; Wolf, Louis; Scheffer-de Gooyert, Jolanda M; Monedero, Ignacio; Torroja, Laura; van der Laak, Jeroen A W M; Schenck, Annette

2017-05-03

Synaptic morphology is tightly related to synaptic efficacy, and in many cases morphological synapse defects ultimately lead to synaptic malfunction. The Drosophila larval neuromuscular junction (NMJ), a well-established model for glutamatergic synapses, has been extensively studied for decades. Identification of mutations causing NMJ morphological defects revealed a repertoire of genes that regulate synapse development and function. Many of these were identified in large-scale studies that focused on qualitative approaches to detect morphological abnormalities of the Drosophila NMJ. A drawback of qualitative analyses is that many subtle players contributing to NMJ morphology likely remain unnoticed. Whereas quantitative analyses are required to detect the subtler morphological differences, such analyses are not yet commonly performed because they are laborious. This protocol describes in detail two image analysis algorithms "Drosophila NMJ Morphometrics" and "Drosophila NMJ Bouton Morphometrics", available as Fiji-compatible macros, for quantitative, accurate and objective morphometric analysis of the Drosophila NMJ. This methodology is developed to analyze NMJ terminals immunolabeled with the commonly used markers Dlg-1 and Brp. Additionally, its wider application to other markers such as Hrp, Csp and Syt is presented in this protocol. The macros are able to assess nine morphological NMJ features: NMJ area, NMJ perimeter, number of boutons, NMJ length, NMJ longest branch length, number of islands, number of branches, number of branching points and number of active zones in the NMJ terminal.

A 20 GHz low noise, low cost receiver for digital satellite communication system, ground terminal applications

NASA Technical Reports Server (NTRS)

Allen, Glen

1988-01-01

A 45 month effort for the development of a 20 GHz, low-noise, low-cost receiver for digital, satellite communication system, ground terminal applications is discussed. Six proof-of-concept receivers were built in two lots of three each. Performance was generally consistent between the two lots. Except for overall noise figure, parameters were within or very close to specification. While noise figure was specified as 3.5 dB, typical performance was measured at 3.0 to 5.5 dB, over the full temperature range of minus 30 C to plus 75 C.

The relationship between sociodemographic factors and reporting having terminated a pregnancy among Ghanaian women: a population-based study.

PubMed

Dankwah, Emmanuel; Steeves, Megan; Ramsay, Dana; Feng, Cindy; Farag, Marwa

2018-05-19

Pregnancy termination is an illegal medical procedure in Ghana and 88% of induced abortions are performed in unsafe conditions, thus recipients face an elevated risk of abortion-related complications. This study aims to explore the associations between sociodemographic factors and reporting having terminated a pregnancy among Ghanaian women. Logistic regression models were estimated using data from the 2014 Ghana Demographic and Health Survey (n=9396). ORs were computed for the associations between reporting pregnancy termination and select demographic and socio-economic factors. Education level, employment status, financial status and marital status of women are significantly associated with reporting having terminated a pregnancy. Women who are employed, cohabit with a partner and are considered middle class or wealthy are more likely than their counterparts to report having terminated a pregnancy. Ghanaian women with intermediate levels of education are more likely than both their more- and less-educated counterparts to report having terminated a pregnancy. These findings highlight the need for the development of policies aimed at reducing unsafe abortions associated with unintended pregnancies. Specific recommendations include providing family planning education and outreach to high-risk groups to reduce unintended pregnancies and improving working conditions for expectant mothers, including provisions for paid maternity leave and job protection.

AIRNOISE: A Tool for Preliminary Noise-Abatement Terminal Approach Route Design

NASA Technical Reports Server (NTRS)

Li, Jinhua; Sridhar, Banavar; Xue, Min; Ng, Hok

2016-01-01

Noise from aircraft in the airport vicinity is one of the leading aviation-induced environmental issues. The FAA developed the Integrated Noise Model (INM) and its replacement Aviation Environmental Design Tool (AEDT) software to assess noise impact resulting from all aviation activities. However, a software tool is needed that is simple to use for terminal route modification, quick and reasonably accurate for preliminary noise impact evaluation and flexible to be used for iterative design of optimal noise-abatement terminal routes. In this paper, we extend our previous work on developing a noise-abatement terminal approach route design tool, named AIRNOISE, to satisfy this criterion. First, software efficiency has been significantly increased by over tenfold using the C programming language instead of MATLAB. Moreover, a state-of-the-art high performance GPU-accelerated computing module is implemented that was tested to be hundreds time faster than the C implementation. Secondly, a Graphical User Interface (GUI) was developed allowing users to import current terminal approach routes and modify the routes interactively to design new terminal approach routes. The corresponding noise impacts are then calculated and displayed in the GUI in seconds. Finally, AIRNOISE was applied to Baltimore-Washington International Airport terminal approach route to demonstrate its usage.

Charge splitters and charge transport junctions based on guanine quadruplexes

NASA Astrophysics Data System (ADS)

Sha, Ruojie; Xiang, Limin; Liu, Chaoren; Balaeff, Alexander; Zhang, Yuqi; Zhang, Peng; Li, Yueqi; Beratan, David N.; Tao, Nongjian; Seeman, Nadrian C.

2018-04-01

Self-assembling circuit elements, such as current splitters or combiners at the molecular scale, require the design of building blocks with three or more terminals. A promising material for such building blocks is DNA, wherein multiple strands can self-assemble into multi-ended junctions, and nucleobase stacks can transport charge over long distances. However, nucleobase stacking is often disrupted at junction points, hindering electric charge transport between the two terminals of the junction. Here, we show that a guanine-quadruplex (G4) motif can be used as a connector element for a multi-ended DNA junction. By attaching specific terminal groups to the motif, we demonstrate that charges can enter the structure from one terminal at one end of a three-way G4 motif, and can exit from one of two terminals at the other end with minimal carrier transport attenuation. Moreover, we study four-way G4 junction structures by performing theoretical calculations to assist in the design and optimization of these connectors.

Phylogenetic relationships within anuran clade Terrarana, with emphasis on the placement of Brazilian Atlantic rainforest frogs genus Ischnocnema (Anura: Brachycephalidae).

PubMed

Canedo, Clarissa; Haddad, Célio F B

2012-11-01

We present a phylogenetic hypothesis of the anuran clade Terrarana based on partial sequences of nuclear (Tyr and RAG1) and mitochondrial (12S, tRNA-Val, and 16S) genes, testing the monophyly of Ischnocnema and its species series. We performed maximum parsimony, maximum likelihood, and Bayesian inference analyses on 364 terminals: 11 outgroup terminals and 353 ingroup Terrarana terminals, including 139 Ischnocnema terminals (accounting for 29 of the 35 named Ischnocnema species) and 214 other Terrarana terminals within the families Brachycephalidae, Ceuthomantidae, Craugastoridae, and Eleutherodactylidae. Different optimality criteria produced similar results and mostly recovered the currently accepted families and genera. According to these topologies, Ischnocnema is not a monophyletic group. We propose new combinations for three species, relocating them to Pristimantis, and render Eleutherodactylus bilineatus Bokermann, 1975 incertae sedis status within Holoadeninae. The rearrangements in Ischnocnema place it outside the northernmost Brazilian Atlantic rainforest, where the fauna of Terrarana comprises typical Amazonian genera. Copyright © 2012 Elsevier Inc. All rights reserved.

32 CFR 1656.11 - Job performance standards and sanctions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... responsible for adhering to the standards of conduct, attitude, appearance and performance demanded by the... to hire him; (3) His employer terminates the ASW's employment because his conduct, attitude...

Biochemical Defense Response: Characterizing the Plasticity of Source and Sink in Spring Wheat under Terminal Heat Stress.

PubMed

Kumar, Ranjeet R; Goswami, Suneha; Shamim, Mohammed; Mishra, Upama; Jain, Monika; Singh, Khushboo; Singh, Jyoti P; Dubey, Kavita; Singh, Shweta; Rai, Gyanendra K; Singh, Gyanendra P; Pathak, Himanshu; Chinnusamy, Viswanathan; Praveen, Shelly

2017-01-01

Wheat is highly prone to terminal heat stress (HS) under late-sown conditions. Delayed- sowing is one of the preferred methods to screen the genotypes for thermotolerance under open field conditions. We investigated the effect of terminal HS on the thermotolerance of four popular genotypes of wheat i.e. WR544, HD2967, HD2932, and HD2285 under field condition. We observed significant variations in the biochemical parameters like protein content, antioxidant activity, proline and total reducing sugar content in leaf, stem, and spike under normal (26 ± 2°C) and terminal HS (36 ± 2°C) conditions. Maximum protein, sugars and proline was observed in HD2967, as compared to other cultivars under terminal HS. Wheat cv. HD2967 showed more adaptability to the terminal HS. Differential protein-profiling in leaves, stem and spike of HD2967 under normal (26 ± 2°C) and terminal HS (36 ± 2°C) showed expression of some unique protein spots. MALDI-TOF/MS analysis showed the DEPs as RuBisCO (Rub), RuBisCO activase (Rca), oxygen evolving enhancer protein (OEEP), hypothetical proteins, etc. Expression analysis of genes associated with photosynthesis ( Rub and Rca ) and starch biosynthesis pathway ( AGPase, SSS and SBE ) showed significant variations in the expression under terminal HS. HD2967 showed better performance, as compared to other cultivars under terminal HS. SSS activity observed in HD2967 showed more stability under terminal HS, as compared with other cultivars. Triggering of different biochemical parameters in response to terminal HS was observed to modulate the plasticity of carbon assimilatory pathway. The identified DEPs will enrich the proteomic resources of wheat and will provide a potential biochemical marker for screening wheat germplasm for thermotolerance. The model hypothesized will help the researchers to work in a more focused way to develop terminal heat tolerant wheat without compromising with the quality and quantity of grains.

The Limiting Velocity in Falling from a Great Height

NASA Technical Reports Server (NTRS)

Wilson, Edwin Bidwell

1919-01-01

The purpose of this report is to give a simple treatment of the problem of calculating the final or limiting velocity of an object falling in vertical motion under gravity in a resisting medium. The equations of motion are easily set up and integrated when the density of the medium is constant and the resistance varies as the square of the velocity. The results show that the fundamental characteristics of the vertical motion under gravity in a resisting medium is the approach to a terminal or limiting velocity, whether the initial downward velocity is less or greater than the limiting velocity. This method can be used to calculate the terminal velocity of a bomb trajectory.

Dynamic Network Drivers of Seizure Generation, Propagation and Termination in Human Neocortical Epilepsy

PubMed Central

Khambhati, Ankit N.; Davis, Kathryn A.; Oommen, Brian S.; Chen, Stephanie H.; Lucas, Timothy H.; Litt, Brian; Bassett, Danielle S.

2015-01-01

The epileptic network is characterized by pathologic, seizure-generating ‘foci’ embedded in a web of structural and functional connections. Clinically, seizure foci are considered optimal targets for surgery. However, poor surgical outcome suggests a complex relationship between foci and the surrounding network that drives seizure dynamics. We developed a novel technique to objectively track seizure states from dynamic functional networks constructed from intracranial recordings. Each dynamical state captures unique patterns of network connections that indicate synchronized and desynchronized hubs of neural populations. Our approach suggests that seizures are generated when synchronous relationships near foci work in tandem with rapidly changing desynchronous relationships from the surrounding epileptic network. As seizures progress, topographical and geometrical changes in network connectivity strengthen and tighten synchronous connectivity near foci—a mechanism that may aid seizure termination. Collectively, our observations implicate distributed cortical structures in seizure generation, propagation and termination, and may have practical significance in determining which circuits to modulate with implantable devices. PMID:26680762

Wound Documentation by Using 3G Mobile as Acquisition Terminal: An Appropriate Proposal for Community Wound Care.

PubMed

Ge, Kui; Wu, Minjie; Liu, Hu; Gong, Jiahong; Zhang, Yi; Hu, Qiang; Fang, Min; Tao, Yanping; Cai, Minqiang; Chen, Hua; Wang, Jianbo; Xie, Ting; Lu, Shuliang

2015-06-01

The increasing numbers of cases of wound disease are now posing a big challenge in China. For more convenience of wound patients, wound management in community health care centers under the supervision of a specialist at general hospitals is an ideal solution. To ensure an accurate diagnosis in community health clinics, it is important that "the same language" for wound description, which may be composed of unified format description, including wound image, must be achieved. We developed a wound information management system that was built up by acquisition terminal, wound description, data bank, and related software. In this system, a 3G mobile phone was applied as acquisition terminal, which could be used to access to the data bank. This documentation system was thought to be an appropriate proposal for community wound care because of its objectivity, uniformity, and facilitation. It also provides possibility for epidemiological study in the future. © The Author(s) 2014.

Electrocardiographic signal-averaging during atrial pacing and effect of cycle length on the terminal QRS in patients with and without inducible ventricular tachycardia.

PubMed

Kremers, M S; Black, W H; Lange, R; Wells, P J; Solo, M

1990-11-01

Electrocardiographic signal-averaging during sinus rhythm (61 to 99 beats/min) and atrial pacing (100 to 171 beats/min) were performed to determine the effect of heart rate on late potentials in 15 patients without (group 1) and 7 patients with (group 2) inducible sustained ventricular tachycardia (VT). In sinus rhythm (79 +/- 12 vs 77 +/- 12 beats/min, difference not significant), the duration of the low-amplitude signal less than 40 microV was longer in group 2 than group 1 (43 +/- 21 vs 26 +/- 8 ms, p = 0.034) and more patients had late potentials (57 vs 7%, p = 0.021), but QRS duration (121 +/- 32 vs 98 +/- 19 ms) and terminal voltage (33 +/- 33 vs 50 +/- 26 ms) were not significantly different. With atrial pacing in group 1 (128 +/- 16 beats/min), 3 patients developed a simultaneous decrease in terminal voltage and an increase in terminal QRS duration consistent with a late potential, but mean total and terminal durations were unchanged. Terminal voltage increased (50 +/- 26 to 59 +/- 40) but not significantly. With atrial pacing in group 2 (119 +/- 12 beats/min) all patients either had a late potential or developed a simultaneous decrease in terminal voltage and an increase in terminal QRS duration (p = 0.001 vs group 1). Root mean square (p = 0.001 vs group 1). Root mean square voltage decreased (33 +/- 23 to 22 +/- 23) and became significantly different from group 1 (p = 0.017). Mean QRS duration, root mean square terminal voltage and low-amplitude terminal QRS duration, however, were unchanged.(ABSTRACT TRUNCATED AT 250 WORDS)

Port of Galveston Solar Energy Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Falcioni, Diane; Cuclis, Alex; Freundlich, Alex

This study on the performance characteristics of existing solar technologies in a maritime environment was funded by an award given to The Port of Galveston (POG) from the U.S. Department of Energy (DOE). The study includes research performed by The Center for Advanced Materials at the University of Houston (UH). The UH researchers examined how solar cell efficiencies and life spans can be improved by examining the performance of a variety of antireflective (AR) coatings mounted on the top of one of the POG’s Cruise Terminals. Supplemental supporting research was performed at the UH laboratories. An educational Kiosk was constructedmore » with a 55” display screen providing information about solar energy, the research work UH performed at POG and real time data from the solar panels located on the roof of the Cruise Terminal. The Houston Advanced Research Center (HARC) managed the project.« less

Partial reinforcement (acquisition) effects within subjects

PubMed Central

Amsel, Abram; MacKinnon, John R.; Rashotte, Michael E.; Surridge, C. Thomas

1964-01-01

Acquisition performance of 22 rats in a straight alley runway was examined. The animals were subjected to partial reinforcement when the alley was black (B±) and continuous reinforcement when it was white (W+). The results indicated (a) higher terminal performance, for partial as against continuous reinforcement conditions, for starting-time and running-time measures, and (b) lower terminal performance under partial conditions for a goal-entry-time measure. These results confirm within subjects an effect previously demonstrated, in the runway, only in between-groups tests, where one group is run under partial reinforcement and a separate group is run under continuous reinforcement in the presence of the same external stimuli. Differences between the runway situation, employing a discrete-trial procedure and performance measures at three points in the response chain, and the Skinner box situation, used in its free-operant mode with a single performance measure, are discussed in relation to the present findings. PMID:14130088

PARTIAL REINFORCEMENT (ACQUISITION) EFFECTS WITHIN SUBJECTS.

PubMed

AMSEL, A; MACKINNON, J R; RASHOTTE, M E; SURRIDGE, C T

1964-03-01

Acquisition performance of 22 rats in a straight alley runway was examined. The animals were subjected to partial reinforcement when the alley was black (B+/-) and continuous reinforcement when it was white (W+). The results indicated (a) higher terminal performance, for partial as against continuous reinforcement conditions, for starting-time and running-time measures, and (b) lower terminal performance under partial conditions for a goal-entry-time measure. These results confirm within subjects an effect previously demonstrated, in the runway, only in between-groups tests, where one group is run under partial reinforcement and a separate group is run under continuous reinforcement in the presence of the same external stimuli. Differences between the runway situation, employing a discrete-trial procedure and performance measures at three points in the response chain, and the Skinner box situation, used in its free-operant mode with a single performance measure, are discussed in relation to the present findings.

Generalized gradient algorithm for trajectory optimization

NASA Technical Reports Server (NTRS)

Zhao, Yiyuan; Bryson, A. E.; Slattery, R.

1990-01-01

The generalized gradient algorithm presented and verified as a basis for the solution of trajectory optimization problems improves the performance index while reducing path equality constraints, and terminal equality constraints. The algorithm is conveniently divided into two phases, of which the first, 'feasibility' phase yields a solution satisfying both path and terminal constraints, while the second, 'optimization' phase uses the results of the first phase as initial guesses.

Conformational ensemble of human α-synuclein physiological form predicted by molecular simulations.

PubMed

Rossetti, G; Musiani, F; Abad, E; Dibenedetto, D; Mouhib, H; Fernandez, C O; Carloni, P

2016-02-17

We perform here enhanced sampling simulations of N-terminally acetylated human α-synuclein, an intrinsically disordered protein involved in Parkinson's disease. The calculations, consistent with experiments, suggest that the post-translational modification leads to the formation of a transient amphipathic α-helix. The latter, absent in the non-physiological form, alters protein dynamics at the N-terminal and intramolecular interactions.

International Space Station Cathode Life Testing

NASA Technical Reports Server (NTRS)

Soulas, George C.; Sarver-Verhey, Timothy R.

1997-01-01

Four hollow cathode assembly (HCA) life tests were initiated at operating conditions simulating on-orbit operation of the International Space Station plasma contactor. The objective of these tests is to demonstrate the mission-required 18,000 hour lifetime with high-fidelity development model HCAS. HCAs are operated with a continuous 6 sccm xenon flow rate and 3 A anode current. On-orbit emission current requirements are simulated with a square waveform consisting of 50 minutes at a 2.5 A emission current and 40 minutes with no emission current. One HCA test was terminated after approximately 8,000 hours so that a destructive analysis could be performed. The analysis revealed no life-limiting processes and the ultimate lifetime was projected to be greater than the mission requirement. Testing continues for the remaining three HCAs which have accumulated approximately 8,000 hours, 10,000 hours, and 11,000 hours, respectively, as of June 1997. Anode and bias voltages, strong indicators of cathode electron emitter condition, are within acceptable ranges and have exhibited no life- or performance-limiting phenomena to date.

Clipping in neurocontrol by adaptive dynamic programming.

PubMed

Fairbank, Michael; Prokhorov, Danil; Alonso, Eduardo

2014-10-01

In adaptive dynamic programming, neurocontrol, and reinforcement learning, the objective is for an agent to learn to choose actions so as to minimize a total cost function. In this paper, we show that when discretized time is used to model the motion of the agent, it can be very important to do clipping on the motion of the agent in the final time step of the trajectory. By clipping, we mean that the final time step of the trajectory is to be truncated such that the agent stops exactly at the first terminal state reached, and no distance further. We demonstrate that when clipping is omitted, learning performance can fail to reach the optimum, and when clipping is done properly, learning performance can improve significantly. The clipping problem we describe affects algorithms that use explicit derivatives of the model functions of the environment to calculate a learning gradient. These include backpropagation through time for control and methods based on dual heuristic programming. However, the clipping problem does not significantly affect methods based on heuristic dynamic programming, temporal differences learning, or policy-gradient learning algorithms.