RHrFPGA Radiation-Hardened Re-programmable Field-Programmable Gate Array

NASA Technical Reports Server (NTRS)

Sanders, A. B.; LaBel, K. A.; McCabe, J. F.; Gardner, G. A.; Lintz, J.; Ross, C.; Golke, K.; Burns, B.; Carts, M. A.; Kim, H. S.

2004-01-01

Viewgraphs on the development of the Radiation-Hardened Re-programmable Field-Programmable Gate Array (RHrFPGA) are presented. The topics include: 1) Radiation Test Suite; 2) Testing Interface; 3) Test Configuration; 4) Facilities; 5) Test Programs; 6) Test Procedure; and 7) Test Results. A summary of heavy ion and proton testing is also included.

ATS-5 12 year in orbit evaluation

NASA Technical Reports Server (NTRS)

Kissel, F. J.; Schaffer, J.

1981-01-01

The results of the ATS 5 End-of-Life (EOL) tests are presented. Whenever possible, the test data were compared with prelaunch and inflight data. Pertinent memos and other informal documents containing these data are included as appendixes. The EOL tests include communication subsystems tests, power sybsystem tests, and gravity gradient television camera system tests.

Wave Energy Prize - 1/50th Testing - Iowec

DOE Data Explorer

Wesley Scharmen

2015-12-18

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the Iowec team, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

Wave Energy Prize - 1/50th Testing - Oscilla Power

DOE Data Explorer

Wesley Scharmen

2016-01-08

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the Oscilla Power team, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

Wave Energy Prize - 1/50th Testing - SEWEC

DOE Data Explorer

Wesley Scharmen

2015-12-11

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the SEWEC team, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

Wave Energy Prize - 1/50th Testing - Principle Power

DOE Data Explorer

Wesley Scharmen

2016-01-08

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the Principle Power team, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

Wave Energy Prize - 1/50th Testing - WECCA

DOE Data Explorer

Wesley Scharmen

2016-01-15

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the WECCA team, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

Wave Energy Prize - 1/50th Testing - Team Flapper/Harvest

DOE Data Explorer

Wesley Scharmen

2015-12-18

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the Team Flapper/Harvest, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

Wave Energy Prize - 1/50th Testing - Sea Potential

DOE Data Explorer

Wesley Scharmen

2015-12-04

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the Sea Potential team, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

Wave Energy Prize - 1/50th Testing - Mocean Energy

DOE Data Explorer

Wesley Scharmen

2016-01-08

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the Mocean Energy team, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

Wave Energy Prize - 1/50th Testing - CalWave

DOE Data Explorer

Wesley Scharmen

2016-01-15

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the CalWave team, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

Wave Energy Prize - 1/50th Testing - AquaHarmonics

DOE Data Explorer

Wesley Scharmen

2016-01-15

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the AquaHarmonics team, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

Test plan and preliminary report of airborne electromagentic environment survey over USA urban areas 0.4 to 18.0 GHz

NASA Technical Reports Server (NTRS)

Taylor, R. E.; Hill, J. S.

1975-01-01

An airborne electromagnetic environment survey is described of five urban areas where terrestrially-generated radio-frequency interference was measured over the frequency range from 0.4 to 18.0 GHz. A chartered Cessna 402 aircraft contained necessary measurement test equipment, including the receiving antennas mounted beneath the fuselage. Urban areas including Washington, D.C.; Baltimore, MD; Philadelphia, PA; New York, NY; Chicago, ILL; and Palestine, TX were surveyed. A flight test plan and preliminary test results for the 0.4 to 1.4 GHz frequency range, are included; a final test report describes more detailed results.

Description and test results of a variable speed, constant frequency generating system

NASA Astrophysics Data System (ADS)

Brady, F. J.

1985-12-01

The variable-speed, constant frequency generating system developed for the Mod-0 wind turbine is presented. This report describes the system as it existed at the conclusion of the project. The cycloconverter control circuit is described including the addition of field-oriented control. The laboratory test and actual wind turbine test results are included.

Design feasibility of an advanced technology supersonic cruise aircraft

NASA Technical Reports Server (NTRS)

Rowe, W. T.

1976-01-01

Research and development programs provide confidence that technology is in-hand to design an economically attractive, environmentally sound supersonic cruise aircraft for commercial operations. The principal results of studies and tests are described including those which define the selection of significant design features. These typically include the results of: (1) wind-tunnel tests, both subsonic and supersonic, (2) propulsion performance and acoustic tests on noise suppressors, including forward-flight effects, (3) studies of engine/airframe integration, which lead to the selection of engine cycles/sizes to meet future market, economic, and social requirements; and (4) structural testing.

Wave Energy Prize - 1/50th Testing - M3 Wave

DOE Data Explorer

Wesley Scharmen

2016-01-08

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the M3 Wave team, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

Wave Energy Prize - 1/50th Testing - RTI Wave Power

DOE Data Explorer

Wesley Scharmen

2015-12-18

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the RTI Wave Power team, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

Wave Energy Prize - 1/50th Testing - Atlas Ocean Systems

DOE Data Explorer

Wesley Scharmen

2015-12-04

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the Atlas Ocean Systems team, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

Impact of Inclusion or Exclusion of Repeaters on Test Equating

ERIC Educational Resources Information Center

Puhan, Gautam

2011-01-01

This study examined the effect of including or excluding repeaters on the equating process and results. New forms of two tests were equated to their respective old forms using either all examinees or only the first timer examinees in the new form sample. Results showed that for both tests used in this study, including or excluding repeaters in the…

The DOE ETV-1 Electric Test Vehicle. Phase 3: Performance Testing and system evaluation

NASA Technical Reports Server (NTRS)

Kurtz, D.

1981-01-01

Engineering tests were conducted in order to characterize overall system performance and component efficiencies within the system environment. A dynamometer was used in order to minimize the ambient effects and large uncertainties present in track testing. Extensive test requirements were defined and procedures were carefully controlled in order to maintain a high degree of credibility. Limited track testing was performed in order to corroborate the dynamometer results. Test results include an energy flow analysis through the major subsystems and incorporate the aerodynamic and rolling losses under cyclic and various steady speed conditions. The major output from all relevant dynamometer and track tests is also included.

9 CFR 51.26 - Record of tests.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Record of tests. 51.26 Section 51.26... each animal. The claimant must provide any information necessary to complete the form. The test record must include the type of test and the test results for each animal. It must also include the individual...

Wave Energy Prize - 1/50th Testing - Advanced Ocean Energy @ VT

DOE Data Explorer

Wesley Scharmen

2016-01-29

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the for the Advanced Ocean Energy @VT team, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

Wave Energy Prize - 1/50th Testing - Super Watt Wave Catcher Barge Team

DOE Data Explorer

Wesley Scharmen

2015-12-04

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the Super Watt Wave Catcher Barge team, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

Advanced Stirling Convertor Dynamic Test Approach and Results

NASA Technical Reports Server (NTRS)

Meer, David W.; Hill, Dennis; Ursic, Joseph

2009-01-01

The U.S. Department of Energy (DOE), Lockheed Martin (LM), and NASA Glenn Research Center (GRC) have been developing the Advanced Stirling Radioisotope Generator (ASRG) for use as a power system for space science missions. As part of the extended operation testing of this power system, the Advanced Stirling Converters (ASC) at NASA John H. Glenn Research Center undergo a vibration test sequence intended to simulate the vibration history of an ASC used in an ASRG for a space mission. This sequence includes testing at Workmanship and Flight Acceptance levels interspersed with periods of extended operation to simulate pre and post fueling. The final step in the test sequence utilizes additional testing at Flight Acceptance levels to simulate launch. To better replicate the acceleration profile seen by an ASC incorporated into an ASRG, the input spectra used in testing the convertors was modified based on dynamic testing of the ASRG Engineering Unit ( ASRG-EU) at Lockheed Martin. This paper presents the vibration test plan for current and future ASC units, including the modified input spectra, and the results of recent tests using these spectra. The test results include data from several accelerometers mounted on the convertors as well as the piston position and output power variables.

Status of 'HIMES' reentry flight test project

NASA Astrophysics Data System (ADS)

Inatani, Yoshifumi; Kawaguchi, Jun'ichiro; Yonemoto, Koichi

1990-10-01

The salient features of the Highly Maneuverable Experimental Space (HIMES) vehicle which is being developed by the Institute of Space and Astronautical Science of Japan are discussed together with the results of tests conducted. Analytical studies carried out so far include system analyses, aerodynamic design, the navigation/guidance and control systems, the propulsion system, and structural studies. Results of flight tests conducted to verify these analyses include the low-speed gliding flight test and the atmospheric reentry flight test, as well as a ground firing test of the hydrogen-fueled propulsion system. Diagrams are presented of the HIMES vehicle and its propulsion engines.

General Dynamic (GD) Launch Waveform On-Orbit Performance Report

NASA Technical Reports Server (NTRS)

Briones, Janette C.; Shalkhauser, Mary Jo

2014-01-01

The purpose of this report is to present the results from the GD SDR on-orbit performance testing using the launch waveform over TDRSS. The tests include the evaluation of well-tested waveform modes, the operation of RF links that are expected to have high margins, the verification of forward return link operation (including full duplex), the verification of non-coherent operational models, and the verification of radio at-launch operational frequencies. This report also outlines the launch waveform tests conducted and comparisons to the results obtained from ground testing.

Advanced Capabilities for Wind Tunnel Testing in the 21st Century

NASA Technical Reports Server (NTRS)

Kegelman, Jerome T.; Danehy, Paul M.; Schwartz, Richard J.

2010-01-01

Wind tunnel testing methods and test technologies for the 21st century using advanced capabilities are presented. These capabilities are necessary to capture more accurate and high quality test results by eliminating the uncertainties in testing and to facilitate verification of computational tools for design. This paper discusses near term developments underway in ground testing capabilities, which will enhance the quality of information of both the test article and airstream flow details. Also discussed is a selection of new capability investments that have been made to accommodate such developments. Examples include advanced experimental methods for measuring the test gas itself; using efficient experiment methodologies, including quality assurance strategies within the test; and increasing test result information density by using extensive optical visualization together with computed flow field results. These points could be made for both major investments in existing tunnel capabilities or for entirely new capabilities.

“Just Because It's Out There, People Aren't Going to Use It.” HIV Self-Testing Among Young, Black MSM, and Transgender Women

PubMed Central

Wilton, Leo; Hirshfield, Sabina; Chiasson, Mary Ann; Usher, DaShawn; Lucy, Debbie; McCrossin, Jermaine; Greene, Emily; Koblin, Beryl

2015-01-01

Abstract HIV disproportionately affects young black MSM and transgender women in the US. Increasing HIV testing rates among these populations is a critical public health goal. Although HIV self-tests are commercially available, there is a need to better understand access to and uptake of HIV self-testing among this population. Here, we report results of a qualitative study of 30 young black MSM and transgender women residing in the New York City area to understand facilitators of and barriers to a range of HIV testing approaches, including self-testing. Mean age was 23.7 years (SD = 3.4). Over half (54%) had some college or an associate's degree, yet 37% had an annual personal income of less than $10,000 per year. Most (64%) participants had tested in the past 6 months; venues included community health/free clinics, medical offices, mobile testing units, hospitals, emergency departments, and research sites. Just one participant reported ever using a commercially available HIV self-test. Facilitators of self-testing included convenience, control, and privacy, particularly as compared to venue-based testing. Barriers to self-testing included the cost of the test, anxiety regarding accessing the test, concerns around correct test operation, and lack of support if a test result is positive. Participants indicated that instruction in correct test operation and social support in the event of a positive test result may increase the likelihood that they would use the self-test. Alongside developing new approaches to HIV prevention, developing ways to increase HIV self-testing is a public health priority for young, black MSM, and transgender women. PMID:26376029

16 CFR 1203.41 - Recordkeeping requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... stability test; (14) The results of the dynamic strength of retention system test; (15) The name and... helmet tests. Complete test records shall be maintained. These records shall contain the following...; (3) The results of the tests, including the precise nature of any failures; (4) A description of the...

16 CFR 1203.41 - Recordkeeping requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... stability test; (14) The results of the dynamic strength of retention system test; (15) The name and... helmet tests. Complete test records shall be maintained. These records shall contain the following...; (3) The results of the tests, including the precise nature of any failures; (4) A description of the...

16 CFR 1203.41 - Recordkeeping requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... stability test; (14) The results of the dynamic strength of retention system test; (15) The name and... helmet tests. Complete test records shall be maintained. These records shall contain the following...; (3) The results of the tests, including the precise nature of any failures; (4) A description of the...

Intelligent transportation systems field operational test cross-cutting study : emergency notification and response.

DOT National Transportation Integrated Search

1998-09-01

Emergency Notification and Response report summarizes and interprets the results of two Field Operational Tests (FOTs) that included emergency notification and response system components. The tests included in this report are: Colorado Mayday and Pug...

Explanation of Two Anomalous Results in Statistical Mediation Analysis

ERIC Educational Resources Information Center

Fritz, Matthew S.; Taylor, Aaron B.; MacKinnon, David P.

2012-01-01

Previous studies of different methods of testing mediation models have consistently found two anomalous results. The first result is elevated Type I error rates for the bias-corrected and accelerated bias-corrected bootstrap tests not found in nonresampling tests or in resampling tests that did not include a bias correction. This is of special…

16 CFR § 1203.41 - Recordkeeping requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

... stability test; (14) The results of the dynamic strength of retention system test; (15) The name and... helmet tests. Complete test records shall be maintained. These records shall contain the following...; (3) The results of the tests, including the precise nature of any failures; (4) A description of the...

40 CFR 92.508 - Calculation and reporting of test results.

Code of Federal Regulations, 2010 CFR

2010-07-01

... specified in § 92.506(a). These results must also include the green engine factor, if applicable. The... engine, including: (A) Configuration and engine family identification; (B) Year, make, and build date; (C... accumulated on locomotive or locomotive engine prior to testing; and (E) Description of green engine factor...

Special Education Students: To Be (Tested) or Not To Be (Tested)? That's a Good Question.

ERIC Educational Resources Information Center

Wilkinson, L. David; Matter, M. Kevin

This paper outlines how the Austin Independent School District (Texas) tried to deal with the following questions: (1) Should special education students be included in the administration of standardized tests?; (2) Should their scores be included or excluded in the reporting of test results?; and (3) What are the evidences that test scores reflect…

ASVCP quality assurance guidelines: external quality assessment and comparative testing for reference and in-clinic laboratories.

PubMed

Camus, Melinda S; Flatland, Bente; Freeman, Kathleen P; Cruz Cardona, Janice A

2015-12-01

The purpose of this document is to educate providers of veterinary laboratory diagnostic testing in any setting about comparative testing. These guidelines will define, explain, and illustrate the importance of a multi-faceted laboratory quality management program which includes comparative testing. The guidelines will provide suggestions for implementation of such testing, including which samples should be tested, frequency of testing, and recommendations for result interpretation. Examples and a list of vendors and manufacturers supplying control materials and services to veterinary laboratories are also included. © 2015 American Society for Veterinary Clinical Pathology.

Analysis of 2004 Round Robin Tests 1 and 4 Data

NASA Technical Reports Server (NTRS)

Hirsch, David; Beeson, Harold

2005-01-01

An analysis of 2004 round robin tests 1 and 4 data is presented. Test 1 burn length test results include: 1) Kydex, WSTF No. 04-38645 25.9% O2 @ 14.3 psia; 2) Kydex, 30% O2 @ 10.2 psia; 3) Royal Blue Cotton, Flame Resistant (WST No. 04-38644) 30% O2 @ 10.2 psia; and 4) Silicone 20.9% O2 @ 14.7 psia. Test 4 burn length test results include: 1) Raychem Electrical Wire, MIL M22759/32-20-9 30% O2 @ 10.2 psia; and 2) Raychem Electrical Wire, MIL M81044/12-20-9 20.9% O2 @ 14.7 psia.

Technical Evaluation Motor No. 7 (TEM-7)

NASA Technical Reports Server (NTRS)

Hughes, Phil

1991-01-01

The Technical Evaluation Motor No. 7 (TEM-7) test was a full-scale, full duration static test firing of a high performance motor-configuration solid rocket motor with nozzle vectoring. The final test report documents the procedures, performance, and results of the static test firing of TEM-7. All observations, discussions, conclusions, and recommendations included in the report are complete and final except for the TEM-7 fixed housing unbond investigation. A presentation and discussion of TEM-7 performance, anomalies, and test result concurrence with the objectives outlined in CTP-0107, Rev A, Space Shuttle Technical Evaluation Motor No. 7 (TEM-7) Static Fire Test Plan are included.

Maraia Capsule Flight Testing and Results for Entry, Descent, and Landing

NASA Technical Reports Server (NTRS)

Sostaric, Ronald R.; Strahan, Alan L.

2016-01-01

The Maraia concept is a modest size (150 lb., 30" diameter) capsule that has been proposed as an ISS based, mostly autonomous earth return capability to function either as an Entry, Descent, and Landing (EDL) technology test platform or as a small on-demand sample return vehicle. A flight test program has been completed including high altitude balloon testing of the proposed capsule shape, with the purpose of investigating aerodynamics and stability during the latter portion of the entry flight regime, along with demonstrating a potential recovery system. This paper includes description, objectives, and results from the test program.

Kinematical Test Theories for Special Relativity

NASA Astrophysics Data System (ADS)

Lämmerzahl, Claus; Braxmaier, Claus; Dittus, Hansjörg; Müller, Holger; Peters, Achim; Schiller, Stephan

A comparison of certain kinematical test theories for Special Relativity including the Robertson and Mansouri-Sext test theories is presented and the accuracy of the experimental results testing Special Relativity are expressed in terms of the parameters appearing in these test theories. The theoretical results are applied to the most precise experimental results obtained recently for the isotropy of light propagation and the constancy of the speed of light.

Test results of the DOE/Sandia 17 meter VAWT

NASA Technical Reports Server (NTRS)

Nellums, R. O.; Worstell, M. H.

1979-01-01

A review is given of the test program of a 17 meter Vertical Axis Wind Turbine VAWT. Performance test results are discussed including difficulties encountered during the VAWT operation along with ways of solving these problems.

Advanced Stirling Convertor Dynamic Test Approach and Results

NASA Technical Reports Server (NTRS)

Meer, David W.; Hill, Dennis; Ursic, Joseph J.

2010-01-01

The U.S. Department of Energy (DOE), Lockheed Martin Corporation (LM), and NASA Glenn Research Center (GRC) have been developing the Advanced Stirling Radioisotope Generator (ASRG) for use as a power system for space science missions. As part of the extended operation testing of this power system, the Advanced Stirling Convertors (ASC) at NASA GRC undergo a vibration test sequence intended to simulate the vibration history that an ASC would experience when used in an ASRG for a space mission. This sequence includes testing at workmanship and flight acceptance levels interspersed with periods of extended operation to simulate prefueling and post fueling. The final step in the test sequence utilizes additional testing at flight acceptance levels to simulate launch. To better replicate the acceleration profile seen by an ASC incorporated into an ASRG, the input spectra used in testing the convertors was modified based on dynamic testing of the ASRG Engineering Unit (ASRG EU) at LM. This paper outlines the overall test approach, summarizes the test results from the ASRG EU, describes the incorporation of those results into the test approach, and presents the results of applying the test approach to the ASC-1 #3 and #4 convertors. The test results include data from several accelerometers mounted on the convertors as well as the piston position and output power variables.

Electrical Arc Ignition Testing of Spacesuit Materials

NASA Technical Reports Server (NTRS)

Smith, Sarah; Gallus, Tim; Tapia, Susana; Ball, Elizabeth; Beeson, Harold

2006-01-01

A viewgraph presentation on electrical arc ignition testing of spacesuit materials is shown. The topics include: 1) Background; 2) Test Objectives; 3) Test Sample Materials; 4) Test Methods; 5) Scratch Test Objectives; 6) Cotton Scratch Test Video; 7) Scratch Test Results; 8) Entire Date Plot; 9) Closeup Data Plot; 10) Scratch Test Problems; 11) Poke Test Objectives; 12) Poke Test Results; 13) Poke Test Problems; 14) Wire-break Test Objectives; 15) Cotton Wire-Break Test Video; 16) High Speed Cotton Wire-break Test Video; 17) Typical Data Plot; 18) Closeup Data Plot; 19) Wire-break Test Results; 20) Wire-break Tests vs. Scratch Tests; 21) Urethane-coated Nylon; and 22) Moleskin.

Reporting Results of Molecular Tests: A Retrospective Examination of BRAF Mutation Reporting.

PubMed

Treece, Amanda L; Gulley, Margaret L; Vasalos, Patricia; Paquette, Cherie; Lindeman, Neal I; Jennings, Lawrence J; Bartley, Angela N

2017-05-01

- With enormous growth in the field of molecular pathology, the reporting of results gleaned from this testing is essential to guide patient care. - To examine molecular reports from laboratories participating in proficiency testing for required elements to convey molecular laboratory test results to clinicians and patients. - Molecular laboratories participating in the College of American Pathologists (CAP) proficiency testing program for BRAF mutation analysis were solicited to submit examples of final reports from 2 separate proficiency testing reporting cycles. Reports were reviewed for the presence or absence of relevant components. - A total of 107 evaluable reports were received (57 demonstrating a positive result for the BRAF V600E mutation and 50 negative). Methods for BRAF testing varied, with 95% (102 of 107) of reports adequately describing their assay methods and 87% (93 of 107) of reports adequately describing the target(s) of their assays. Information on the analytic sensitivity of the assay was present in 74% (79 of 107) of reports and 83% (89 of 107) reported at least 1 assay limitation, though only 34% (36 of 107) reported on variants not detected by their assays. Analytic and clinical interpretive comments were included in 99% (106 of 107) and 90% (96 of 107) of reports, respectively. Of participants that perform a laboratory-developed test, 88% (88 of 100) included language addressing the development of the assay. - Laboratories participating in BRAF proficiency testing through the CAP are including most of the required reporting elements to unambiguously convey molecular results. Laboratories should continue to strive to report these results in a concise and comprehensive manner.

Test and Evaluation of the Navy Technical Information Presentation System (NTIPS) F-14A Field Test Results

DTIC Science & Technology

1988-09-01

Test and Evaluation Report Test and Evaluation of the Navy Technical Information Presentation System (NTIPS) F-14A Field Test Results by .0 Joseph J...PROGRAM PROJECT TASK WORK UNIT Washington, D.C. 20361 ELEMENT NO. NO. NO. ACCESSION NO. OMN 1820 11. TITLE (Include Security Classification) TEST AND...EVALUATION OF THE NAVY TECHNICAL INFORMATION PRESENTATION SYSTEM (NTIPS) F-14A FIELD TEST RESULTS 12. PERSONAL AUTHOR(S) Fuller, Joseph F. (DTRC) Post

Developing software to "track and catch" missed follow-up of abnormal test results in a complex sociotechnical environment.

PubMed

Smith, M; Murphy, D; Laxmisan, A; Sittig, D; Reis, B; Esquivel, A; Singh, H

2013-01-01

Abnormal test results do not always receive timely follow-up, even when providers are notified through electronic health record (EHR)-based alerts. High workload, alert fatigue, and other demands on attention disrupt a provider's prospective memory for tasks required to initiate follow-up. Thus, EHR-based tracking and reminding functionalities are needed to improve follow-up. The purpose of this study was to develop a decision-support software prototype enabling individual and system-wide tracking of abnormal test result alerts lacking follow-up, and to conduct formative evaluations, including usability testing. We developed a working prototype software system, the Alert Watch And Response Engine (AWARE), to detect abnormal test result alerts lacking documented follow-up, and to present context-specific reminders to providers. Development and testing took place within the VA's EHR and focused on four cancer-related abnormal test results. Design concepts emphasized mitigating the effects of high workload and alert fatigue while being minimally intrusive. We conducted a multifaceted formative evaluation of the software, addressing fit within the larger socio-technical system. Evaluations included usability testing with the prototype and interview questions about organizational and workflow factors. Participants included 23 physicians, 9 clinical information technology specialists, and 8 quality/safety managers. Evaluation results indicated that our software prototype fit within the technical environment and clinical workflow, and physicians were able to use it successfully. Quality/safety managers reported that the tool would be useful in future quality assurance activities to detect patients who lack documented follow-up. Additionally, we successfully installed the software on the local facility's "test" EHR system, thus demonstrating technical compatibility. To address the factors involved in missed test results, we developed a software prototype to account for technical, usability, organizational, and workflow needs. Our evaluation has shown the feasibility of the prototype as a means of facilitating better follow-up for cancer-related abnormal test results.

Effects of handcuffs on neuropsychological testing: Implications for criminal forensic evaluations.

PubMed

Biddle, Christine M; Fazio, Rachel L; Dyshniku, Fiona; Denney, Robert L

2018-01-01

Neuropsychological evaluations are increasingly performed in forensic contexts, including in criminal settings where security sometimes cannot be compromised to facilitate evaluation according to standardized procedures. Interpretation of nonstandardized assessment results poses significant challenges for the neuropsychologist. Research is limited in regard to the validation of neuropsychological test accommodation and modification practices that deviate from standard test administration; there is no published research regarding the effects of hand restraints upon neuropsychological evaluation results. This study provides preliminary results regarding the impact of restraints on motor functioning and common neuropsychological tests with a motor component. When restrained, performance on nearly all tests utilized was significantly impacted, including Trail Making Test A/B, a coding test, and several tests of motor functioning. Significant performance decline was observed in both raw scores and normative scores. Regression models are also provided in order to help forensic neuropsychologists adjust for the effect of hand restraints on raw scores of these tests, as the hand restraints also resulted in significant differences in normative scores; in the most striking case there was nearly a full standard deviation of discrepancy.

Genetic Diagnosis and Testing in Clinical Practice

PubMed Central

McPherson, Elizabeth

2006-01-01

Genetic testing is defined as “the analysis of human DNA, RNA, chromosomes, proteins and certain metabolites in order to detect heritable disease-related genotypes, mutations, phenotypes or karyotypes for clinical purposes.” This article focuses on diagnostic and predictive genetic testing. The latter includes presymptomatic testing, which identifies individuals who are expected to become ill in the future and predisposition testing, which identifies those who are at increased risk of becoming ill. Decisions regarding genetic testing must be based not only on the analytic accuracy, availability and cost of the test, but on the clinical utility as well, including the sensitivity, specificity and interpretability of results. Clinical information, including the medical and family history and the findings of the physical examination, is vital for the selection of appropriate diagnostic tests, as well as the interpretation of the results. Presymptomatic genetic testing is a very personal choice that should only be made after the patient has had sufficient counseling to develop an understanding of the risks and benefits of the test and is able to make an informed decision. The same principle applies to predisposition testing; however, additional factors, such as the probability of a positive result, the likelihood that the disease will actually develop in those with positive results, the effect on the management of the index patient, the effects on family members, the risk of false reassurance if the result is negative or the potential for loss of hope if it is positive, all contribute to the assessment of risk versus benefit. Clinical evaluation and counseling of the patient who is at risk for a genetic disorder are labor intensive but essential for the selection and interpretation of genetic tests. PMID:16809405

Space Station CMIF extended duration metabolic control test

NASA Technical Reports Server (NTRS)

Schunk, Richard G.; Bagdigian, Robert M.; Carrasquillo, Robyn L.; Ogle, Kathryn Y.; Wieland, Paul O.

1989-01-01

The Space Station Extended Duration Metabolic Control Test (EMCT) was conducted at the MSFC Core Module Integration Facility. The primary objective of the EMCT was to gather performance data from a partially-closed regenerative Environmental Control and Life Support (ECLS) system functioning under steady-state conditions. Included is a description of the EMCT configuration, a summary of events, a discussion of anomalies that occurred during the test, and detailed results and analysis from individual measurements of water and gas samples taken during the test. A comparison of the physical, chemical, and microbiological methods used in the post test laboratory analyses of the water samples is included. The preprototype ECLS hardware used in the test, providing an overall process description and theory of operation for each hardware item. Analytical results pertaining to a system level mass balance and selected system power estimates are also included.

Delivering safe and effective test-result communication, management and follow-up: a mixed-methods study protocol.

PubMed

Dahm, Maria R; Georgiou, Andrew; Westbrook, Johanna I; Greenfield, David; Horvath, Andrea R; Wakefield, Denis; Li, Ling; Hillman, Ken; Bolton, Patrick; Brown, Anthony; Jones, Graham; Herkes, Robert; Lindeman, Robert; Legg, Michael; Makeham, Meredith; Moses, Daniel; Badmus, Dauda; Campbell, Craig; Hardie, Rae-Anne; Li, Julie; McCaughey, Euan; Sezgin, Gorkem; Thomas, Judith; Wabe, Nasir

2018-02-15

The failure to follow-up pathology and medical imaging test results poses patient-safety risks which threaten the effectiveness, quality and safety of patient care. The objective of this project is to: (1) improve the effectiveness and safety of test-result management through the establishment of clear governance processes of communication, responsibility and accountability; (2) harness health information technology (IT) to inform and monitor test-result management; (3) enhance the contribution of consumers to the establishment of safe and effective test-result management systems. This convergent mixed-methods project triangulates three multistage studies at seven adult hospitals and one paediatric hospital in Australia.Study 1 adopts qualitative research approaches including semistructured interviews, focus groups and ethnographic observations to gain a better understanding of test-result communication and management practices in hospitals, and to identify patient-safety risks which require quality-improvement interventions.Study 2 analyses linked sets of routinely collected healthcare data to examine critical test-result thresholds and test-result notification processes. A controlled before-and-after study across three emergency departments will measure the impact of interventions (including the use of IT) developed to improve the safety and quality of test-result communication and management processes.Study 3 adopts a consumer-driven approach, including semistructured interviews, and the convening of consumer-reference groups and community forums. The qualitative data will identify mechanisms to enhance the role of consumers in test-management governance processes, and inform the direction of the research and the interpretation of findings. Ethical approval has been granted by the South Eastern Sydney Local Health District Human Research Ethics Committee and Macquarie University. Findings will be disseminated in academic, industry and consumer journals, newsletters and conferences. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Developing Software to “Track and Catch” Missed Follow-up of Abnormal Test Results in a Complex Sociotechnical Environment

PubMed Central

Smith, M.; Murphy, D.; Laxmisan, A.; Sittig, D.; Reis, B.; Esquivel, A.; Singh, H.

2013-01-01

Summary Background Abnormal test results do not always receive timely follow-up, even when providers are notified through electronic health record (EHR)-based alerts. High workload, alert fatigue, and other demands on attention disrupt a provider’s prospective memory for tasks required to initiate follow-up. Thus, EHR-based tracking and reminding functionalities are needed to improve follow-up. Objectives The purpose of this study was to develop a decision-support software prototype enabling individual and system-wide tracking of abnormal test result alerts lacking follow-up, and to conduct formative evaluations, including usability testing. Methods We developed a working prototype software system, the Alert Watch And Response Engine (AWARE), to detect abnormal test result alerts lacking documented follow-up, and to present context-specific reminders to providers. Development and testing took place within the VA’s EHR and focused on four cancer-related abnormal test results. Design concepts emphasized mitigating the effects of high workload and alert fatigue while being minimally intrusive. We conducted a multifaceted formative evaluation of the software, addressing fit within the larger socio-technical system. Evaluations included usability testing with the prototype and interview questions about organizational and workflow factors. Participants included 23 physicians, 9 clinical information technology specialists, and 8 quality/safety managers. Results Evaluation results indicated that our software prototype fit within the technical environment and clinical workflow, and physicians were able to use it successfully. Quality/safety managers reported that the tool would be useful in future quality assurance activities to detect patients who lack documented follow-up. Additionally, we successfully installed the software on the local facility’s “test” EHR system, thus demonstrating technical compatibility. Conclusion To address the factors involved in missed test results, we developed a software prototype to account for technical, usability, organizational, and workflow needs. Our evaluation has shown the feasibility of the prototype as a means of facilitating better follow-up for cancer-related abnormal test results. PMID:24155789

NEXT Single String Integration Test Results

NASA Technical Reports Server (NTRS)

Soulas, George C.; Patterson, Michael J.; Pinero, Luis; Herman, Daniel A.; Snyder, Steven John

2010-01-01

As a critical part of NASA's Evolutionary Xenon Thruster (NEXT) test validation process, a single string integration test was performed on the NEXT ion propulsion system. The objectives of this test were to verify that an integrated system of major NEXT ion propulsion system elements meets project requirements, to demonstrate that the integrated system is functional across the entire power processor and xenon propellant management system input ranges, and to demonstrate to potential users that the NEXT propulsion system is ready for transition to flight. Propulsion system elements included in this system integration test were an engineering model ion thruster, an engineering model propellant management system, an engineering model power processor unit, and a digital control interface unit simulator that acted as a test console. Project requirements that were verified during this system integration test included individual element requirements ; integrated system requirements, and fault handling. This paper will present the results of these tests, which include: integrated ion propulsion system demonstrations of performance, functionality and fault handling; a thruster re-performance acceptance test to establish baseline performance: a risk-reduction PMS-thruster integration test: and propellant management system calibration checks.

Common Allergens Identified Based on Patch Test Results in Patients with Suspected Contact Dermatitis of the Scalp

PubMed Central

Aleid, Nouf M.; Fertig, Raymond; Maddy, Austin; Tosti, Antonella

2017-01-01

Background Contact dermatitis of the scalp is common and might be caused by many chemicals including metals, ingredients of shampoos and conditioners, dyes, or other hair treatments. Eliciting a careful history and patch tests are necessary to identify the responsible allergen and prevent relapses. Objectives To identify allergens that may cause contact dermatitis of the scalp by reviewing patch test results. Methods We reviewed the records of 1,015 patients referred for patch testing at the Dermatology Department of the University of Miami. A total of 226 patients (205 females and 21 males) with suspected scalp contact dermatitis were identified, and the patch test results and clinical data for those patients were analyzed. Most patients were referred for patch testing from a specialized hair clinic at our institution. Results The most common allergens in our study population were nickel (23.8%), cobalt (21.0%), balsam of Peru (18.2%), fragrance mix (14.4%), carba mix (11.6%), and propylene glycol (PG) (8.8%). The majority of patients were females aged 40–59 years, and scalp itching or burning were reported as the most common symptom. Conclusion Frequent sources of allergens for metals include hair clasps, pins, and brushes, while frequent sources of allergens for preservatives, fragrance mix, and balsam of Peru include shampoos, conditioners, and hair gels. Frequent sources of allergens for PG include topical medications. PMID:28611994

Surface tension propellant control for Viking 75 Orbiter

NASA Technical Reports Server (NTRS)

Dowdy, M. W.; Hise, R. E.; Peterson, R. G.; Debrock, S. C.

1976-01-01

The paper describes the selection, development and qualification of the surface tension system and includes results of low-g drop tower tests of scale models, 1-g simulation tests of low-g large ullage settling and liquid withdrawal, structural qualification tests, and propellant surface tension/contact angle studies. Subscale testing and analyses were used to evaluate the ability of the system to maintain or recover the desired propellant orientation following possible disturbances during the Viking mission. This effort included drop tower tests to demonstrate that valid wick paths exist for moving any displaced propellant back over the tank outlet. Variations in surface tension resulting from aging, temperature, and lubricant contamination were studied and the effects of surface finish, referee fluid exposure, aging, and lubricant contamination on contact angle were assessed. Results of movies of typical subscale drop tower tests and full scale slosh tests are discussed.

Physical Test Prototypes Based on Microcontroller

NASA Astrophysics Data System (ADS)

Paramitha, S. T.

2017-03-01

The purpose of this study was to produce a prototype of a physical test-based microcontroller. The research method uses the research and development of the Borg and gall. The procedure starts from the study; research and information collecting, planning, develop preliminary form of product, preliminary field testing, main product revision, playing field testing, operational product revision, field operational testing, final product revision, dissemination and implementation. Validation of the product, obtained through expert evaluation; test products of small scale and large scale; effectiveness test; evaluation of respondents. The results showed that the eligibility assessment of prototype products based physical tests microcontroller. Based on the ratings of seven experts showed that 87% included in the category of “very good” and 13% included in the category of “good”. While the effectiveness of the test results showed that 1). The results of the experimental group to test sit-ups increase by 40% and the control group by 15%. 2). The results of the experimental group to test push-ups increased by 30% and the control group by 10%. 3). The results of the experimental group to test the Back-ups increased by 25% and the control group by 10%. With a significant value of 0.002 less than 0.05, product means a physical test prototype microcontroller based, proven effective in improving the results of physical tests. Conclusions and recommendations; Product physical microcontroller-based assays, can be used to measure the physical tests of pushups, sit ups, and back-ups.

Ground Test of the Urine Processing Assembly for Accelerations and Transfer Functions

NASA Technical Reports Server (NTRS)

Houston, Janice; Almond, Deborah F. (Technical Monitor)

2001-01-01

This viewgraph presentation gives an overview of the ground test of the urine processing assembly for accelerations and transfer functions. Details are given on the test setup, test data, data analysis, analytical results, and microgravity assessment. The conclusions of the tests include the following: (1) the single input/multiple output method is useful if the data is acquired by tri-axial accelerometers and inputs can be considered uncorrelated; (2) tying coherence with the matrix yields higher confidence in results; (3) the WRS#2 rack ORUs need to be isolated; (4) and future work includes a plan for characterizing performance of isolation materials.

RERTR-12 Insertion 2 Irradiation Summary Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

D. M. Perez; G. S. Chang; D. M. Wachs

2012-09-01

The Reduced Enrichment for Research and Test Reactor (RERTR) experiment RERTR-12 was designed to provide comprehensive information on the performance of uranium-molybdenum (U-Mo) based monolithic fuels for research reactor applications.1 RERTR-12 insertion 2 includes the capsules irradiated during the last three irradiation cycles. These capsules include Z, Y1, Y2 and Y3 type capsules. The following report summarizes the life of the RERTR-12 insertion 2 experiment through end of irradiation, including as-run neutronic analysis results, thermal analysis results and hydraulic testing results.

Uprated OMS Engine Status-Sea Level Testing Results

NASA Technical Reports Server (NTRS)

Bertolino, J. D.; Boyd, W. C.

1990-01-01

The current Space Shuttle Orbital Maneuvering Engine (OME) is pressure fed, utilizing storable propellants. Performance uprating of this engine, through the use of a gas generator driven turbopump to increase operating pressure, is being pursued by the NASA Johnson Space Center (JSC). Component level design, fabrication, and test activities for this engine system have been on-going since 1984. More recently, a complete engine designated the Integrated Component Test Bed (ICTB), was tested at sea level conditions by Aerojet. A description of the test hardware and results of the sea level test program are presented. These results, which include the test condition operating envelope and projected performance at altitude conditions, confirm the capability of the selected Uprated OME (UOME) configuration to meet or exceed performance and operational requirements. Engine flexibility, demonstrated through testing at two different operational mixture ratios, along with a summary of projected Space Shuttle performance enhancements using the UOME, are discussed. Planned future activities, including ICTB tests at simulated altitude conditions, and recommendations for further engine development, are also discussed.

LabRS: A Rosetta stone for retrospective standardization of clinical laboratory test results.

PubMed

Hauser, Ronald George; Quine, Douglas B; Ryder, Alex

2018-02-01

Clinical laboratories in the United States do not have an explicit result standard to report the 7 billion laboratory tests results they produce each year. The absence of standardized test results creates inefficiencies and ambiguities for secondary data users. We developed and tested a tool to standardize the results of laboratory tests in a large, multicenter clinical data warehouse. Laboratory records, each of which consisted of a laboratory result and a test identifier, from 27 diverse facilities were captured from 2000 through 2015. Each record underwent a standardization process to convert the original result into a format amenable to secondary data analysis. The standardization process included the correction of typos, normalization of categorical results, separation of inequalities from numbers, and conversion of numbers represented by words (eg, "million") to numerals. Quality control included expert review. We obtained 1.266 × 109 laboratory records and standardized 1.252 × 109 records (98.9%). Of the unique unstandardized records (78.887 × 103), most appeared <5 times (96%, eg, typos), did not have a test identifier (47%), or belonged to an esoteric test with <100 results (2%). Overall, these 3 reasons accounted for nearly all unstandardized results (98%). Current results suggest that the tool is both scalable and generalizable among diverse clinical laboratories. Based on observed trends, the tool will require ongoing maintenance to stay current with new tests and result formats. Future work to develop and implement an explicit standard for test results would reduce the need to retrospectively standardize test results. © The Author 2017. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com

Solar thermal upper stage technology demonstrator liquid hydrogen storage and feed system test program

NASA Astrophysics Data System (ADS)

Cady, E. C.

1997-01-01

The Solar Thermal Upper Stage Technology Demonstrator (STUSTD) Liquid Hydrogen Storage and Feed System (LHSFS) Test Program is described. The test program consists of two principal phases. First, an engineering characterization phase includes tests performed to demonstrate and understand the expected tank performance. This includes fill and drain; baseline heat leak; active Thermodynamic Vent System (TVS); and flow tests. After the LHSFS performance is understood and performance characteristics are determined, a 30 day mission simulation test will be conducted. This test will simulate a 30 day transfer mission from low earth orbit (LEO) to geosynchronous equatorial orbit (GEO). Mission performance predictions, based on the results of the engineering characterization tests, will be used to correlate the results of the 30 day mission simulation.

Structural, Thermal, and Optical Performance (STOP) Modeling and Results for the James Webb Space Telescope Integrated Science Instrument Module

NASA Technical Reports Server (NTRS)

Gracey, Renee; Bartoszyk, Andrew; Cofie, Emmanuel; Comber, Brian; Hartig, George; Howard, Joseph; Sabatke, Derek; Wenzel, Greg; Ohl, Raymond

2016-01-01

The James Webb Space Telescope includes the Integrated Science Instrument Module (ISIM) element that contains four science instruments (SI) including a Guider. We performed extensive structural, thermal, and optical performance(STOP) modeling in support of all phases of ISIM development. In this paper, we focus on modeling and results associated with test and verification. ISIMs test program is bound by ground environments, mostly notably the 1g and test chamber thermal environments. This paper describes STOP modeling used to predict ISIM system performance in 0g and at various on-orbit temperature environments. The predictions are used to project results obtained during testing to on-orbit performance.

Responsive Multimodal Transportation Management Strategies And IVHS

DOT National Transportation Integrated Search

1998-09-01

Emergency Notification and Response report summarizes and interprets the results of two Field Operational Tests (FOTs) that included emergency notification and response system components. The tests included in this report are: Colorado Mayday and Pug...

CPAS Preflight Drop Test Analysis Process

NASA Technical Reports Server (NTRS)

Englert, Megan E.; Bledsoe, Kristin J.; Romero, Leah M.

2015-01-01

Throughout the Capsule Parachute Assembly System (CPAS) drop test program, the CPAS Analysis Team has developed a simulation and analysis process to support drop test planning and execution. This process includes multiple phases focused on developing test simulations and communicating results to all groups involved in the drop test. CPAS Engineering Development Unit (EDU) series drop test planning begins with the development of a basic operational concept for each test. Trajectory simulation tools include the Flight Analysis and Simulation Tool (FAST) for single bodies, and the Automatic Dynamic Analysis of Mechanical Systems (ADAMS) simulation for the mated vehicle. Results are communicated to the team at the Test Configuration Review (TCR) and Test Readiness Review (TRR), as well as at Analysis Integrated Product Team (IPT) meetings in earlier and intermediate phases of the pre-test planning. The ability to plan and communicate efficiently with rapidly changing objectives and tight schedule constraints is a necessity for safe and successful drop tests.

Test result communication in primary care: clinical and office staff perspectives.

PubMed

Litchfield, Ian J; Bentham, Louise M; Lilford, Richard J; Greenfield, Sheila M

2014-10-01

To understand how the results of laboratory tests are communicated to patients in primary care and perceptions on how the process may be improved. Qualitative study employing staff focus groups. Four UK primary care practices. Staff involved in the communication of test results. Five main themes emerged from the data: (i) the default method for communicating results differed between practices; (ii) clinical impact of results and patient characteristics such as anxiety level or health literacy influenced methods by which patients received their test result; (iii) which staff member had responsibility for the task was frequently unclear; (iv) barriers to communicating results existed, including there being no system or failsafe in place to determine whether results were returned to a practice or patient; (v) staff envisaged problems with a variety of test result communication methods discussed, including use of modern technologies, such as SMS messaging or online access. Communication of test results is a complex yet core primary care activity necessitating flexibility by both patients and staff. Dealing with the results from increasing numbers of tests is resource intensive and pressure on practice staff can be eased by greater utilization of electronic communication. Current systems appear vulnerable with no routine method of tracing delayed or missing results. Instead, practices only become aware of missing results following queries from patients. The creation of a test communication protocol for dissemination among patients and staff would help ensure both groups are aware of their roles and responsibilities. © The Author 2014. Published by Oxford University Press.

An overview of key technology thrusts at Bell Helicopter Textron

NASA Technical Reports Server (NTRS)

Harse, James H.; Yen, Jing G.; Taylor, Rodney S.

1988-01-01

Insight is provided into several key technologies at Bell. Specific topics include the results of ongoing research and development in advanced rotors, methodology development, and new configurations. The discussion on advanced rotors highlight developments on the composite, bearingless rotor, including the development and testing of full scale flight hardware as well as some of the design support analyses and verification testing. The discussion on methodology development concentrates on analytical development in aeromechanics, including correlation studies and design application. New configurations, presents the results of some advanced configuration studies including hardware development.

Design, fabrication and test of graphite/polyimide composite joints and attachments for advanced aerospace vehicles

NASA Technical Reports Server (NTRS)

Barclay, D. L.

1980-01-01

Results of an experimental program to develop several types of graphite/polyimide (GR/PI) bonded and bolted joints for lightly loaded flight components for advanced space transportation systems and high speed aircraft are presented. Tasks accomplished include: a literature survey; design of static discriminator specimens; design allowables testing; fabrication of test panels and specimens; small specimen testing; and standard joint testing. Detail designs of static discriminator specimens for each of the four major attachment types are presented. Test results are given for the following: (1) transverse tension of Celion 3000/PMR-15 laminate; (2) net tension of a laminate for both a loaded and unloaded bolt hole; (3) comparative testing of bonded and co-cured doublers along with pull-off tests of single and double bonded angles; (4) single lap shear tests, transverse tension and coefficient of thermal expansion tests of A7F (LARC-13 amide-imide modified) adhesive; and (5) tension tests of standard single lap, double lap, and symmetric step lap bonded joints. Also, included are results of a finite element analysis of a single lap bonded composite joint.

The evaluation of a number of prototypes for the free-tip rotor constant-moment controller

NASA Technical Reports Server (NTRS)

Young, L. A.

1986-01-01

The development of several prototypes of a constant moment controller, a critical component of the free-tip rotor (FTR) concept, is described. Also presented are the experimental results of a whirl test designed to select a final controller configuration to be included in a future wind-tunnel test of this innovative rotor system. A brief explanation of the FTR concept and its history are included. The paper documents the controller design constraints, each prototype's operating principle, the evaluation test, and the individual prototype test results. A recommended design is identified, along with the selection rationale.

Ice Shape Scaling for Aircraft in SLD Conditions

NASA Technical Reports Server (NTRS)

Anderson, David N.; Tsao, Jen-Ching

2008-01-01

This paper has summarized recent NASA research into scaling of SLD conditions with data from both SLD and Appendix C tests. Scaling results obtained by applying existing scaling methods for size and test-condition scaling will be reviewed. Large feather growth issues, including scaling approaches, will be discussed briefly. The material included applies only to unprotected, unswept geometries. Within the limits of the conditions tested to date, the results show that the similarity parameters needed for Appendix C scaling also can be used for SLD scaling, and no additional parameters are required. These results were based on visual comparisons of reference and scale ice shapes. Nearly all of the experimental results presented have been obtained in sea-level tunnels. The currently recommended methods to scale model size, icing limit and test conditions are described.

Correlations of Platooning Track Test and Wind Tunnel Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lammert, Michael P.; Kelly, Kenneth J.; Yanowitz, Janet

In this report, the National Renewable Energy Laboratory analyzed results from multiple, independent truck platooning projects to compare and contrast track test results with wind tunnel test results conducted by Lawrence Livermore National Laboratory (LLNL). Some highlights from the report include compiled data, and results from four independent SAE J1321 full-size track test campaigns that were compared to LLNL wind tunnel testing results. All platooning scenarios tested demonstrated significant fuel savings with good correlation relative to following distances, but there are still unanswered questions and clear opportunities for system optimization. NOx emissions showed improvements from NREL tests in 2014 tomore » Auburn tests in 2015 with respect to J1321 platooning track testing of Peloton system. NREL evaluated data from Volpe's Naturalistic Study of Truck Following Behavior, which showed minimal impact of naturalistic background platooning. We found significant correlation between multiple track studies, wind tunnel tests, and computational fluid dynamics, but also showed that there is more to learn regarding close formation and longer-distance effects. We also identified potential areas for further research and development, including development of advanced aerodynamic designs optimized for platooning, measurement of platoon system performance in traffic conditions, impact of vehicle lateral offsets on platooning performance, and characterization of the national potential for platooning based on fleet operational characteristics.« less

Finite Element Analysis and Test Results Comparison for the Hybrid Wing Body Center Section Test Article

NASA Technical Reports Server (NTRS)

Przekop, Adam; Jegley, Dawn C.; Rouse, Marshall; Lovejoy, Andrew E.

2016-01-01

This report documents the comparison of test measurements and predictive finite element analysis results for a hybrid wing body center section test article. The testing and analysis efforts were part of the Airframe Technology subproject within the NASA Environmentally Responsible Aviation project. Test results include full field displacement measurements obtained from digital image correlation systems and discrete strain measurements obtained using both unidirectional and rosette resistive gauges. Most significant results are presented for the critical five load cases exercised during the test. Final test to failure after inflicting severe damage to the test article is also documented. Overall, good comparison between predicted and actual behavior of the test article is found.

Analysis of results from wind tunnel tests of inlets for an advanced turboprop nacelle installation

NASA Technical Reports Server (NTRS)

Hancock, J. P.; Lyman, V.; Pennock, A. P.

1986-01-01

Inlets for tractor installations of advanced turboprop propulsion systems were tested in three phases, covering a period from November, 1982 to January, 1984. Nacelle inlet configuration types included single scoop, twin scoop, and annular arrangements. Tests were performed with and without boundary layer diverters and several different diverter heights were tested for the single scoop inlet. This same inlet was also tested at two different axial positions. Test Mach numbers ranged from Mach 0.20 to 0.80. Types of data taken were: (1) internal and external pressures, including inlet throat recoveries; (2) balance forces, including thrust-minus-drag; and (3) propellar blade stresses.

Pathology Reports

MedlinePlus

... pathology report will include the results of these tests. For example, the pathology report may include information obtained from ... markers or indicators of a specific cancer. For example, the Philadelphia chromosome ... ( 3 ). Some tests that might be performed on a tissue sample ...

Assuring the Quality of Test Results in the Field of Nuclear Techniques and Ionizing Radiation. The Practical Implementation of Section 5.9 of the EN ISO/IEC 17025 Standard

NASA Astrophysics Data System (ADS)

Cucu, Daniela; Woods, Mike

2008-08-01

The paper aims to present a practical approach for testing laboratories to ensure the quality of their test results. It is based on the experience gained in assessing a large number of testing laboratories, discussing with management and staff, reviewing results obtained in national and international PTs and ILCs and exchanging information in the EA laboratory committee. According to EN ISO/IEC 17025, an accredited laboratory has to implement a programme to ensure the quality of its test results for each measurand. Pre-analytical, analytical and post-analytical measures shall be applied in a systematic manner. They shall include both quality control and quality assurance measures. When designing the quality assurance programme a laboratory should consider pre-analytical activities (like personnel training, selection and validation of test methods, qualifying equipment), analytical activities ranging from sampling, sample preparation, instrumental analysis and post-analytical activities (like decoding, calculation, use of statistical tests or packages, management of results). Designed on different levels (analyst, quality manager and technical manager), including a variety of measures, the programme shall ensure the validity and accuracy of test results, the adequacy of the management system, prove the laboratory's competence in performing tests under accreditation and last but not least show the comparability of test results. Laboratory management should establish performance targets and review periodically QC/QA results against them, implementing appropriate measures in case of non-compliance.

A study of short test and charge retention test methods for nickel-cadmium spacecraft cells

NASA Technical Reports Server (NTRS)

Scott, W. R.

1975-01-01

Methods for testing nickel-cadmium cells for internal shorts and charge retention were studied. Included were (a) open circuit voltage decay after a brief charge, (b) open circuit voltage recovery after shorting, and (c) open circuit voltage decay and capacity loss after a full charge. The investigation included consideration of the effects of prior history, of conditioning cells prior to testing, and of various test method variables on the results of the tests. Sensitivity of the tests was calibrated in terms of equivalent external resistance. The results were correlated. It was shown that a large number of variables may affect the results of these tests. It is concluded that the voltage decay after a brief charge and the voltage recovery methods are more sensitive than the charged stand method, and can detect an internal short equivalent to a resistance of about (10,000/C)ohms where "C' is the numerical value of the capacity of the cell in ampere hours.

Quiet Clean Short-haul Experimental Engine (QCSEE) Under-The-Wing (UTW) engine composite nacelle test report. Volume 1: Summary, aerodynamic and mechanical performance

NASA Technical Reports Server (NTRS)

1979-01-01

The performance test results of the final under-the-wing engine configuration are presented. One hundred and six hours of engine operation were completed, including mechanical and performance checkout, baseline acoustic testing with a bellmouth inlet, reverse thrust testing, acoustic technology tests, and limited controls testing. The engine includes a variable pitch fan having advanced composite fan blades and using a ball-spline pitch actuation system.

Initial test results using the GEOS-3 engineering model altimeter

NASA Technical Reports Server (NTRS)

Hayne, G. S.; Clary, J. B.

1977-01-01

Data from a series of experimental tests run on the engineering model of the GEOS 3 radar altimeter using the Test and Measurement System (TAMS) designed for preflight testing of the radar altimeter are presented. These tests were conducted as a means of preparing and checking out a detailed test procedure to be used in running similar tests on the GEOS 3 protoflight model altimeter systems. The test procedures and results are also included.

40 CFR 1048.205 - What must I include in my application?

Code of Federal Regulations, 2010 CFR

2010-07-01

...? 1048.205 Section 1048.205 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... following: (1) Emission data from transient testing of engines using measurement systems designed for.... (s) Report test results as follows: (1) Report all test results involving measurement of pollutants...

Scaled Tank Test Design and Results for the Aquantis 2.5 MW Ocean Current Generation Device

DOE Data Explorer

Swales, Henry; Kils, Ole; Coakley, David B.; Sites, Eric; Mayer, Tyler

2015-06-03

Aquantis 2.5 MW Ocean Current Generation Device, Tow Tank Dynamic Rig Structural Analysis Results. This is the detailed documentation for scaled device testing in a tow tank, including models, drawings, presentations, cost of energy analysis, and structural analysis. This dataset also includes specific information on drivetrain, roller bearing, blade fabrication, mooring, and rotor characteristics.

Overcoming barriers to HIV testing: preferences for new strategies among clients of a needle exchange, a sexually transmitted disease clinic, and sex venues for men who have sex with men.

PubMed

Spielberg, Freya; Branson, Bernard M; Goldbaum, Gary M; Lockhart, David; Kurth, Ann; Celum, Connie L; Rossini, Anthony; Critchlow, Cathy W; Wood, Robert W

2003-03-01

To determine strategies to overcome barriers to HIV testing among persons at risk. We developed a survey that elicited testing motivators, barriers, and preferences for new strategies among 460 participants at a needle exchange, three sex venues for men who have sex with men, and a sexually transmitted disease clinic. Barriers to testing included factors influenced by individual concern (fear and discrimination); by programs, policies, and laws (named reporting and inability to afford treatment); and by counseling and testing strategies (dislike of counseling, anxiety waiting for results, and venipuncture). The largest proportions of participants preferred rapid testing strategies, including clinic-based testing (27%) and home self-testing (20%); roughly equal proportions preferred oral fluid testing (18%), urine testing (17%), and standard blood testing (17%). One percent preferred home specimen collection. Participants who had never tested before were significantly more likely to prefer home self-testing compared with other strategies. Blacks were significantly more likely to prefer urine testing. Strategies for improving acceptance of HIV counseling and testing include information about access to anonymous testing and early treatment. Expanding options for rapid testing, urine testing, and home self-testing; providing alternatives to venipuncture; making pretest counseling optional; and allowing telephone results disclosure may encourage more persons to learn their HIV status.

Pilot study: assessing the clinical diagnosis of allergy in atopic children using a microarray assay in addition to skin prick testing and serum specific IgE.

PubMed

Foong, Ru-Xin; Roberts, Graham; Fox, Adam Tobias; du Toit, George

2016-01-01

Children with atopic dermatitis (AD) are at risk of developing allergy. Alongside clinical history, testing modalities include skin prick tests (SPT), specific immunoglobulin-E (sp-IgE) and recently, microarray assays. The aim of this pilot study was to assess current tests and the ISAC sIgE-112 system in the diagnosis of food and aeroallergen allergy. Children aged 0-11 years with moderate to severe AD were included. An initial allergy assessment including clinical history, SPT and sp-IgE was performed to determine food and aeroallergen sensitization. A second independent clinical assessment using the same information given to the first assessor and ISAC test results for food and aeroallergen sensitization was also made for each participant. The results from both were compared. 30 children [mean age 3.91 years (SD 3.3)] were included; 53.3 and 46.7 % had moderate and severe AD, respectively. Sp-IgE tests had a higher percentage of positive results compared to SPT and ISAC tests for common allergens. There was a significant difference between the three tests in detecting aeroallergen sensitization (p = 0.038), especially between sp-IgE and ISAC tests, but no significant difference between the tests for food allergen sensitization. There was good agreement between the two assessors; 70 % of the children had a change in diagnosis, with 60 % having at least one diagnosis added and 40 % having at least one diagnosis removed. There is a role for the use of ISAC testing in diagnosing sensitization and allergy in children with AD as it leads to a change in diagnosis for many patients. Further work is required to assess its clinical and cost effectiveness.

QM-8 final performance evaluation report: SEALS, volume 4

NASA Technical Reports Server (NTRS)

Nelsen, L. V.

1989-01-01

The Space Shuttle Redesigned Solid Rocket Motor (RSRM) static test of Qualification Motor-8 (QM-8) was conducted. The QM-8 test article was the fifth full-scale, full-duration test, and the third qualification motor to incorporate the redesigned case field joint and nozzle-to-case joint. This was the second static test conducted in the T-97 test facility, which is equipped with actuators for inducing external side loads to a 360 degree external tank (ET) attach ring during test motor operation, and permits heating/cooling of an entire motor. The QM-8 motor was cooled to a temperature which ensured that the maximum propellant mean bulk temperature (PMBT) of 40 F was achieved at firing. All test results are not included, but rather, the performance of the metal case, field joints, and nozzle-to-case joint is addressed. The involvement is studied of the Structural Applications and Structural Design Groups with the QM-8 test which includes: assembly procedures of the field and nozzle-to-case joints, joint leak check results, structural test results, and post-test inspection evaluations.

Common pressure vessel battery performance

NASA Technical Reports Server (NTRS)

Otzinger, B.

1978-01-01

Performance tests run on two common pressure vessel type nickel hydrogen batteries are described and the results presented. The study included: (1) charge retention tests, (2) synchronous eclipse season cycling tests, and (3) temperature differential tests.

Development of a facility using robotics for testing automation of inertial instruments

NASA Technical Reports Server (NTRS)

Greig, Joy Y.; Lamont, Gary B.; Biezad, Daniel J.; Lewantowicz, Zdsislaw H.; Greig, Joy Y.

1987-01-01

The Integrated Robotics System Simulation (ROBSIM) was used to evaluate the performance of the PUMA 560 arm as applied to testing of inertial sensors. Results of this effort were used in the design and development of a feasibility test environment using a PUMA 560 arm. The implemented facility demonstrated the ability to perform conventional static inertial instrument tests (rotation and tumble). The facility included an efficient data acquisitions capability along with a precision test servomechanism function resulting in various data presentations which are included in the paper. Analysis of inertial instrument testing accuracy, repeatability and noise characteristics are provided for the PUMA 560 as well as for other possible commercial arm configurations. Another integral aspect of the effort was an in-depth economic analysis and comparison of robot arm testing versus use of contemporary precision test equipment.

Flight test results of the Strapdown hexad Inertial Reference Unit (SIRU). Volume 1: Flight test summary

NASA Technical Reports Server (NTRS)

Hruby, R. J.; Bjorkman, W. S.

1977-01-01

Flight test results of the strapdown inertial reference unit (SIRU) navigation system are presented. The fault-tolerant SIRU navigation system features a redundant inertial sensor unit and dual computers. System software provides for detection and isolation of inertial sensor failures and continued operation in the event of failures. Flight test results include assessments of the system's navigational performance and fault tolerance.

Prevalence and correlates of human immunodeficiency virus testing and posttest counseling among outpatients with serious mental illness.

PubMed

Desai, Mayur M; Rosenheck, Robert A; Desai, Rani A

2007-09-01

This study examined the prevalence and correlates of receipt of human immunodeficiency virus (HIV) testing, test results, and posttest counseling among outpatients with serious mental illness at 3 public-sector facilities in Connecticut (N = 487). A substantial proportion (41.9%) reported never having been tested for HIV, including fully one-third of those who were "very afraid" of getting acquired immune deficiency syndrome. Independent correlates of HIV testing included younger age, felony criminal history, stronger therapeutic alliance with one's primary clinician, and increased drug problems and psychological distress. Of those tested, nearly all (96.5%) reported receiving the test results; however, only half (50.5%) reported receiving any posttest counseling. Independent correlates of posttest counseling included higher educational level, felony criminal history, and receipt of community-based case management services. Greater efforts are needed to increase HIV testing and counseling among persons with serious mental illness to better identify and care for HIV-positive individuals and potentially reduce future transmission of the virus in this vulnerable, at-risk population.

Overseas testing of a multisensor landmine detection system: results and lessons learned

NASA Astrophysics Data System (ADS)

Keranen, Joe G.; Topolosky, Zeke

2009-05-01

The Nemesis detection system has been developed to provide an efficient and reliable unmanned, multi-sensor, groundbased platform to detect and mark landmines. The detection system consists of two detection sensor arrays: a Ground Penetrating Synthetic Aperture Radar (GPSAR) developed by Planning Systems, Inc. (PSI) and an electromagnetic induction (EMI) sensor array developed by Minelab Electronics, PTY. Limited. Under direction of the Night Vision and Electronic Sensors Directorate (NVESD), overseas testing was performed at Kampong Chhnang Test Center (KCTC), Cambodia, from May 12-30, 2008. Test objectives included: evaluation of detection performance, demonstration of real-time visualization and alarm generation, and evaluation of system operational efficiency. Testing was performed on five sensor test lanes, each consisting of a unique soil mixture and three off-road lanes which include curves, overgrowth, potholes, and non-uniform lane geometry. In this paper, we outline the test objectives, procedures, results, and lessons learned from overseas testing. We also describe the current state of the system, and plans for future enhancements and modifications including clutter rejection and feature-level fusion.

Status of the Flooding Fragility Testing Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pope, C. L.; Savage, B.; Bhandari, B.

2016-06-01

This report provides an update on research addressing nuclear power plant component reliability under flooding conditions. The research includes use of the Component Flooding Evaluation Laboratory (CFEL) where individual components and component subassemblies will be tested to failure under various flooding conditions. The resulting component reliability data can then be incorporated with risk simulation strategies to provide a more thorough representation of overall plant risk. The CFEL development strategy consists of four interleaved phases. Phase 1 addresses design and application of CFEL with water rise and water spray capabilities allowing testing of passive and active components including fully electrified components.more » Phase 2 addresses research into wave generation techniques followed by the design and addition of the wave generation capability to CFEL. Phase 3 addresses methodology development activities including small scale component testing, development of full scale component testing protocol, and simulation techniques including Smoothed Particle Hydrodynamic (SPH) based computer codes. Phase 4 involves full scale component testing including work on full scale component testing in a surrogate CFEL testing apparatus.« less

Subsonic stability and control flight test results of the Space Shuttle /tail cone off/

NASA Technical Reports Server (NTRS)

Cooke, D. R.

1980-01-01

The subsonic stability and control testing of the Space Shuttle Orbiter in its two test flights in the tailcone-off configuration is discussed, and test results are presented. Flight test maneuvers were designed to maximize the quality and quantity of stability and control data in the minimal time allotted using the Space Shuttle Functional Simulator and the Modified Maximum Likelihood Estimator (MMLE) programs, and coefficients were determined from standard sensor data sets using the MMLE, despite problems encountered in timing due to the different measurement systems used. Results are included for lateral directional and longitudinal maneuvers as well as the Space Shuttle aerodynamic data base obtained using the results of wind tunnel tests. The flight test data are found to permit greater confidence in the data base since the differences found are well within control system capability. It is suggested that the areas of major differences, including lateral directional data with open speedbrake, roll due to rudder and normal force due to elevon, be investigated in any further subsonic flight testing. Improvements in sensor data and data handling techniques for future orbital test flights are indicated.

Analysis, design, fabrication and testing of the mini-Brayton rotating unit (Mini-BRU). Volume 1: Text and tables

NASA Technical Reports Server (NTRS)

Dobler, F. X.

1978-01-01

A 500 to 2100 watt power output Mini-Brayton Rotating Unit (Mini-BRU)was analyzed, designed, fabricated and tested. Performance and test data for the various components is included. Components tested include the 2.12 in. diameter compressor, the 2.86 in. diameter turbine, the Rice alternator and the cantilevered foil-type journal and thrust bearings. Also included are results on the fabrication of a C-103 turbine plenum/nozzle assembly and on offgassing of the organic materials in the alternator stator.

Pretest analysis document for Semiscale Test S-LH-1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shaw, R.A.

Results from various pretest calculations which were performed for Test S-LH-1 are included in this report. Test S-LH-1 has been designed to produce primary liquid holdup in the steam generator U-tubes similar to Tests S-UT-8. The analyses included in this report indicate liquid will be held in the tubes, the core liquid level will be appropriately depressed, and a core heater rod temperature excursion should occur. Several sensitivity studies are also included which identify parameters which could affect the response.

Use of proficiency test performance to determine clinical laboratory director qualifications.

PubMed

Howanitz, P J

1988-04-01

Many activities and policies influence laboratory test quality. Proficiency test results are one measure of laboratory quality, and during the past 25 years, five studies have examined the relationship of laboratory director educational requirements to proficiency test results. Data from three studies support the association between director qualifications and quality as measured by proficiency test performance, whereas no relationship was found in the other two studies. Possible reasons for conflicting results include differences in database size and demographics; in addition, proficiency test results may be inappropriate, although widely used, as the sole measure of laboratory director performance.

Zum Problem des Tests, insbesondere des Einstufungstests, im Deutschunterricht fuer Auslaender (On the Problem of Tests, Particularly Placement Tests, in Teaching German to Foreigners)

ERIC Educational Resources Information Center

Breitung, H. A.; And Others

1974-01-01

New placement procedure at Humboldt University includes interviews and placement tests. Interviews reveal response ability, tempo, pronunciation, comprehension, etc. The 60-minute test that follows is described and results discussed, as well as difficulty level and grading. Results: better grouping of students, less shifting, better work. (Text is…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huskey, A.; Bowen, A.; Jager, D.

This test was conducted as part of the U.S. Department of Energy's (DOE) Independent Testing project. This project was established to help reduce the barriers to wind energy expansion by providing independent testing results for small wind turbines (SWT). In total, five turbines were tested at the National Wind Technology Center (NWTC) as a part of this project. Safety and function testing is one of up to five tests performed on the turbines, including power performance, duration, noise, and power-quality tests. NWTC testing results provide manufacturers with reports that may be used to meet part of small wind turbine certificationmore » requirements. The test equipment includes a Mariah Windspire wind turbine mounted on a monopole tower. L&E Machine manufactured the turbine in the United States. The inverter was manufactured separately by Technology Driven Products in the United States. The system was installed by the NWTC site operations group with guidance and assistance from Mariah Power.« less

Environmentally Friendly Corrosion Preventative Compounds

NASA Technical Reports Server (NTRS)

Calle, Luz Marina; Montgomery, Eliza; Kolody, Mark; Curran, Jerry; Back, Teddy; Balles, Angela

2012-01-01

The objective of the Ground Systems Development and Operations Program Environmentally Friendly Corrosion Protective Coatings and Corrosion Preventive Compounds (CPCs) project is to identify, test, and develop qualification criteria for the use of environmentally friendly corrosion protective coatings and CPCs for flight hardware and ground support equipment. This document is the Final Report for Phase I evaluations, which included physical property, corrosion resistance, and NASA spaceport environment compatibility testing and analysis of fifteen CPC types. The CPCs consisted of ten different oily film CPCs and five different wax or grease CPC types. Physical property testing encompassed measuring various properties of the bulk CPCs, while corrosion resistance testing directly measured the ability of each CPC material to protect various metals against corrosion. The NASA spaceport environment compatibility testing included common tests required by NASA-STD-6001, "Flammability, Odor, Offgassing, and Compatibility Requirements and Test Procedures for Materials in Environments that Support Combustion". At the end of Phase I, CPC materials were down-selected for inclusion in the next test phases. This final report includes all data and analysis of results obtained by following the experimental test plan that was developed as part of the project. Highlights of the results are summarized by test criteria type.

Component qualification and initial build of the AGT 100 advanced automotive gas turbine

NASA Technical Reports Server (NTRS)

Johnson, R. A.

1983-01-01

In advance of initial dynamometer testing of the AGT 100 engine, all prime components and subsystems were bench/rig tested. Included were compressor, combustor, turbines, regenerator, ceramic components, and electronic control system. Results are briefly reviewed. Initial engine buildup was completed and rolled-out for test cell installation in July 1982. Shakedown testing included motoring and sequential firing of the combustor's three fuel nozzles.

Geotechnical Centrifuge Experiments to Evaluate Piping in Foundation Soils

DTIC Science & Technology

2014-05-01

verifiable results. These tests were successful in design , construction, and execution of a realistic simulation of internal erosion leading to failure...possible “scale effects,” “modeling of models” testing protocol should be included in the test program. Also, the model design should minimize the scale...recommendations for improving the centrifuge tests include the following: • Design improved system for reservoir control to provide definitive and

Construction quality assurance report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roscha, V.

1994-09-08

This report provides a summary of the construction quality assurance (CQA) observation and test results, including: The results of the geosynthetic and soil materials conformance testing. The observation and testing results associates with the installation of the soil liners. The observation and testing results associated with the installation of the HDPE geomembrane liner systems. The observation and testing results associated with the installation of the leachate collection and removal systems. The observation and testing results associated with the installation of the working surfaces. The observation and testing results associated with in-plant manufacturing process. Summary of submittal reviews by Golder Constructionmore » Services, Inc. The submittal and certification of the piping material specifications. The observation and verification associated of the Acceptance Test Procedure results of the operational equipment functions. Summary of the ECNs which are incorporated into the project.« less

Evaluating performance in sweat testing in medical biochemistry laboratories in Croatia

PubMed Central

Aralica, Merica; Krleza, Jasna Lenicek

2017-01-01

Introduction Sweat test has a diagnostic role in evaluation of cystic fibrosis. Its performance includes sweat stimulation, collection and analysis. All listed may be sources of inconsistencies in everyday practice. The aim of this study was an evaluation of external quality assessment (EQA) of sweat chloride measurement including sweat test performance in medical biochemistry laboratories in Croatia. Materials and methods EQA for sweat chloride measurement was provided by Croatian Centre for Quality Assessment in Laboratory Medicine (CROQALM) in five consecutive exercises to medical biochemistry laboratories (MBL) that offered sweat testing. A questionnaire regarding all phases of testing was mailed to involved MBL (N = 10). Survey results were compared to current guidelines for sweat test performance. Results Reported results of EQA in 2015 exercises showed coefficients of variation (CV) from 28.9%, 29.0% to 35.3%, respectively. An introduction of uniform sweat chloride measurement protocol resulted in CV of 15.5% and 14.7% reported in following two exercises in 2016. All MBL included in this study replied to the questionnaire. Results reported by MBL indicated: lack of patient information policy (7/10), use of unacceptable electrodes (6/9), misuse of minimum of acceptable sweat weight (6/9), lack of internal quality assessment (5/9) and recommended reference ranges (5/9 and 4/9). Agreements to guidelines were found in approach to unsuitable patients (9/10) and sweat collection (8/9). Conclusion Presented results indicate major weak points of current practice in sweat test performance in Croatian MBL and stress the need for its standardization on a national level. PMID:28392735

Evaluation of rapid HIV test kits on whole blood and development of rapid testing algorithm for voluntary testing and counseling centers in Ethiopia.

PubMed

Tegbaru, Belete; Messele, Tsehaynesh; Wolday, Dawit; Meles, PhD Hailu; Tesema, Desalegn; Birhanu, Hiwot; Tesfaye, Girma; Bond, Kyle B; Martin, Robert; Rayfield, Mark A; Wuhib, Tadesse; Fekadu, Makonnen

2004-10-01

Five simple and rapid HIV antibody detection assays viz. Determine, Capillus, Oraquick, Unigold and Hemastrip were evaluated to examine their performance and to develop an alternative rapid test based testing algorithm for voluntary counseling and testing (VCT) in Ethiopia. All the kits were tested on whole blood, plasma and serum. The evaluation had three phases: Primary lab review, piloting at point of service and implementation. This report includes the results of the first two phases. A total of 2,693 specimens (both whole blood and plasma) were included in the evaluation. Results were compared to double Enzyme Linked Immuno-Sorbent Assay (ELISA) system. Discordant EIA results were resolved using Western Blot. The assays had very good sensitivities and specificities, 99-100%, at the two different phases of the evaluation. A 98-100% result agreement was obtained from those tested at VCT centers and National Referral Laboratory for AIDS (NRLA), in the quality control phase of the evaluation. A testing strategy yielding 100% [95% CI; 98.9-100.0] sensitivity was achieved by the sequential use of the three rapid test kits. Direct cost comparison showed serial testing algorithm reduces the cost of testing by over 30% compared to parallel testing in the current situation. Determine, Capillus/Oraquick (presence/absence of frefrigeration) and Unigold were recommended as screening, confirmation and tiebreaker tests, respectively.

Arcjet Testing of Micro-Meteoroid Impacted Thermal Protection Materials

NASA Technical Reports Server (NTRS)

Agrawal, Parul; Munk, Michelle M.; Glaab, Louis J.

2013-01-01

There are several harsh space environments that could affect thermal protection systems and in turn pose risks to the atmospheric entry vehicles. These environments include micrometeoroid impact, extreme cold temperatures, and ionizing radiation during deep space cruise, all followed by atmospheric entry heating. To mitigate these risks, different thermal protection material samples were subjected to multiple tests, including hyper velocity impact, cold soak, irradiation, and arcjet testing, at various NASA facilities that simulated these environments. The materials included a variety of honeycomb packed ablative materials as well as carbon-based non-ablative thermal protection systems. The present paper describes the results of the multiple test campaign with a focus on arcjet testing of thermal protection materials. The tests showed promising results for ablative materials. However, the carbon-based non-ablative system presented some concerns regarding the potential risks to an entry vehicle. This study provides valuable information regarding the capability of various thermal protection materials to withstand harsh space environments, which is critical to sample return and planetary entry missions.

Genetic susceptibility testing for neurodegenerative diseases: Ethical and practice issues

PubMed Central

Roberts, J. Scott; Uhlmann, Wendy R.

2013-01-01

As the genetics of neurodegenerative disease become better understood, opportunities for genetic susceptibility testing for at-risk individuals will increase. Such testing raises important ethical and practice issues related to test access, informed consent, risk estimation and communication, return of results, and policies to prevent genetic discrimination. The advent of direct-to-consumer genetic susceptibility testing for various neurodegenerative disorders (including Alzheimer’s disease, Parkinson’s disease, and certain prion diseases) means that ethical and practical challenges must be faced not only in traditional research and clinical settings, but also in broader society. This review addresses several topics relevant to the development and implementation of genetic susceptibility tests across research, clinical, and consumer settings; these include appropriate indications for testing, the implications of different methods for disclosing test results, clinical versus personal utility of risk information, psychological and behavioral responses to test results, testing of minors, genetic discrimination, and ethical dilemmas posed by whole-genome sequencing. We also identify future areas of likely growth in the field, including pharmacogenomics and genetic screening for individuals considering or engaged in activities that pose elevated risk of brain injury (e.g., football players, military personnel). APOE gene testing for risk of Alzheimer’s disease is used throughout as an instructive case example, drawing upon the authors’ experience as investigators in a series of multisite randomized clinical trials that have examined the impact of disclosing APOE genotype status to interested individuals (e.g., first-degree relatives, persons with mild cognitive impairment). PMID:23583530

Pap and HPV Testing

Cancer.gov

Pap tests detect abnormal cervical cells, including precancerous cervical lesions, as well as early cervical cancers. HPV tests detect HPV infections that can cause cervical cell abnormalities. Learn how Pap and HPV tests are done, how often testing should be done, and how are HPV test results are reported.

Investigation of optimized graded concrete for Oklahoma.

DOT National Transportation Integrated Search

2013-07-01

This report presents the results of several novel test methods to investigate concrete for slip formed paving. These tests include the Box Test, a novel test to evaluate the response of concrete to vibration, the AIMS2, an automated test for aggregat...

Evaluation of the impact of lime softening waste disposal in natural environments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blaisi, Nawaf I.; Roessler, Justin; Cheng, Weizhi

2015-09-15

Highlights: • Leaching tests conducted on WTR to assess potential for trace element release. • Aluminum leaching found to be elevated with respect to risk threshold. • Release in anaerobic conditions evaluated with column test run in nitrogen chamber. • Increased release of certain elements seen from residues under anaerobic conditions. • Different leaching tests produced results on two sides of regulatory threshold. - Abstract: Drinking water treatment residues (WTR), generated from the lime softening processes, are commonly reused or disposed of in a number of applications; these include use as a soil amendment or a subsurface fill. Recently questionsmore » were posed by the Florida regulatory community on whether lime WTR that contained a small percentage of other treatment additives could appropriately be characterized as lime WTR, in terms of total element content and leachability. A study was done using a broad range of leaching tests, including a framework of tests recently adopted by the United States-Environmental Protection Agency (EPA) and tests that were modified to account for scenario specific conditions, such as the presence of natural organic matter (NOM). The results of these additional leaching tests demonstrated that certain applications, including disposal in a water body with NOM or in placement anaerobic environment, did result in increased leaching of elements such as Fe, and that a site specific assessment should be conducted prior to using WTR in these types of applications. This study illustrates the importance of leaching test selection when attempting to provide an estimation of release in practice. Although leaching tests are just one component in a beneficial use assessment and other factors including aquifer and soil properties play a significant role in the outcome, leaching tests should be tailored to most appropriately represent the scenario or reuse application being evaluated.« less

The 5K70SK automatically tuned, high power, S-band klystron

NASA Technical Reports Server (NTRS)

Goldfinger, A.

1977-01-01

Primary objectives include delivery of 44 5K70SK klystron amplifier tubes and 26 remote tuner assemblies with spare parts kits. Results of a reliability demonstration on a klystron test cavity are discussed, along with reliability tests performed on a remote tuning unit. Production problems and one design modification are reported and discussed. Results of PAT and DVT are included.

Identifying and regulating carcinogens. Background paper

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1987-11-01

Contents include: Introduction and summary; policies for testing, assessing, and regulating carcinogens; federal agency assessment and regulation of carcinogens; the national toxicology program; agency responses to the annual report on carcinogens and NCI/NTP test results; statutory authority for regulating carcinogens; chemicals listed in annual report on carcinogens and NCI/NTP test results.

Flight test results of the strapdown hexad inertial reference unit (SIRU). Volume 2: Test report

NASA Technical Reports Server (NTRS)

Hruby, R. J.; Bjorkman, W. S.

1977-01-01

Results of flight tests of the Strapdown Inertial Reference Unit (SIRU) navigation system are presented. The fault tolerant SIRU navigation system features a redundant inertial sensor unit and dual computers. System software provides for detection and isolation of inertial sensor failures and continued operation in the event of failures. Flight test results include assessments of the system's navigational performance and fault tolerance. Performance shortcomings are analyzed.

Direct-to-Consumer Genetic Testing: Helping Patients Make Informed Choices
.

PubMed

Mahon, Suzanne M

2018-02-01

Using direct-to-consumer genetic testing (DTCGT), individuals can order a genetic test, collect and submit a saliva sample, and obtain results about their genetic risk for a variety of traits and health conditions without involving a healthcare provider. Potential benefits of DTCGT include personal control over genetic information and health management decisions, whereas potential risks include misinterpretation of results, psychosocial distress, and lack of informed consent. Oncology nurses can provide education, support, and advocacy to enable patients to truly understand the positives and negatives associated with DTCGT.
.

A device for testing cables

NASA Technical Reports Server (NTRS)

Hayhurst, Arthur Ray (Inventor)

1993-01-01

A device for testing current paths is attachable to a conductor. The device automatically checks the current paths of the conductor for continuity of a center conductor, continuity of a shield, and a short circuit between the shield and the center conductor. The device includes a pair of connectors and a circuit to provide for testing of the conductive paths of a cable to be tested with the circuit paths of the circuit. The circuit paths in the circuit include indicators to simultaneously indicate the results of the testing.

Track-train dynamic analysis and test program, truck static test

NASA Technical Reports Server (NTRS)

Nemes, A. G.

1974-01-01

A series of tests were conducted to define the characteristics of an ASF 11 Ride Truck Assembly including joint slop, friction and stiffness. Loading to the truck assembly included vertical load to simulate the car/pool loading combined with lateral or moment loading that resulted in desired truck deflections for the various phases of testing. All seven test conditions were successfully completed with load and deflection data being collected. No attempt is made to reduce the applicable data other than to provide computer plots.

DC to DC Converter Testing for Space Applications: Use of EMI Filters and Thermal Range of Operation

NASA Technical Reports Server (NTRS)

Leon, Rosa

2008-01-01

Several tests were performed on Interpoint and International Rectifier (IR) direct current (DC) to DC converters to evaluate potential performance and reliability issues in space use of DC to DC converters and to determine if the use of electromagnetic interference (EMI) filters mitigates concerns observed during previous tests. Test findings reported here include those done up until September - October 2008. Tests performed include efficiency, regulation, cross-regulation, power consumption with inhibit on, load transient response, synchronization, and turn-on tests. Some of the test results presented here span the thermal range -55 C to 125 C. Lower range was extended to -120 C in some tested converters. Determination of failure root cause in DC/DC converters that failed at thermal extremes is also included.

40 CFR 75.59 - Certification, quality assurance, and quality control record provisions.

Code of Federal Regulations, 2011 CFR

2011-07-01

...-minute readings and the run average); (B) The raw data and results for all required pre-test, post-test... error tests, and all off-line calibration demonstrations, including any follow-up tests after corrective... tests, a test number and reason for test; (ix) For 7-day calibration tests for certification or...

40 CFR 75.59 - Certification, quality assurance, and quality control record provisions.

Code of Federal Regulations, 2013 CFR

2013-07-01

...-minute readings and the run average); (B) The raw data and results for all required pre-test, post-test... error tests, and all off-line calibration demonstrations, including any follow-up tests after corrective... tests, a test number and reason for test; (ix) For 7-day calibration tests for certification or...

40 CFR 75.59 - Certification, quality assurance, and quality control record provisions.

Code of Federal Regulations, 2012 CFR

2012-07-01

...-minute readings and the run average); (B) The raw data and results for all required pre-test, post-test... error tests, and all off-line calibration demonstrations, including any follow-up tests after corrective... tests, a test number and reason for test; (ix) For 7-day calibration tests for certification or...

40 CFR 75.59 - Certification, quality assurance, and quality control record provisions.

Code of Federal Regulations, 2014 CFR

2014-07-01

...-minute readings and the run average); (B) The raw data and results for all required pre-test, post-test... error tests, and all off-line calibration demonstrations, including any follow-up tests after corrective... tests, a test number and reason for test; (ix) For 7-day calibration tests for certification or...

The Effect of Adaptive Nonlinear Frequency Compression on Phoneme Perception.

PubMed

Glista, Danielle; Hawkins, Marianne; Bohnert, Andrea; Rehmann, Julia; Wolfe, Jace; Scollie, Susan

2017-12-12

This study implemented a fitting method, developed for use with frequency lowering hearing aids, across multiple testing sites, participants, and hearing aid conditions to evaluate speech perception with a novel type of frequency lowering. A total of 8 participants, including children and young adults, participated in real-world hearing aid trials. A blinded crossover design, including posttrial withdrawal testing, was used to assess aided phoneme perception. The hearing aid conditions included adaptive nonlinear frequency compression (NFC), static NFC, and conventional processing. Enabling either adaptive NFC or static NFC improved group-level detection and recognition results for some high-frequency phonemes, when compared with conventional processing. Mean results for the distinction component of the Phoneme Perception Test (Schmitt, Winkler, Boretzki, & Holube, 2016) were similar to those obtained with conventional processing. Findings suggest that both types of NFC tested in this study provided a similar amount of speech perception benefit, when compared with group-level performance with conventional hearing aid technology. Individual-level results are presented with discussion around patterns of results that differ from the group average.

Hawaiian Electric Advanced Inverter Test Plan - Result Summary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoke, Anderson; Nelson, Austin; Prabakar, Kumaraguru

This presentation is intended to share the results of lab testing of five PV inverters with the Hawaiian Electric Companies and other stakeholders and interested parties. The tests included baseline testing of advanced inverter grid support functions, as well as distribution circuit-level tests to examine the impact of the PV inverters on simulated distribution feeders using power hardware-in-the-loop (PHIL) techniques. hardware-in-the-loop (PHIL) techniques.

CERCA LEU fuel assemblies testing in Maria Reactor - safety analysis summary and testing program scope.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pytel, K.; Mieleszczenko, W.; Lechniak, J.

2010-03-01

The presented paper contains neutronic and thermal-hydraulic (for steady and unsteady states) calculation results prepared to support annex to Safety Analysis Report for MARIA reactor in order to obtain approval for program of testing low-enriched uranium (LEU) lead test fuel assemblies (LTFA) manufactured by CERCA. This includes presentation of the limits and operational constraints to be in effect during the fuel testing investigations. Also, the scope of testing program (which began in August 2009), including additional measurements and monitoring procedures, is described.

Effect of Harm Anchors in Visual Displays of Test Results on Patient Perceptions of Urgency About Near-Normal Values: Experimental Study.

PubMed

Zikmund-Fisher, Brian J; Scherer, Aaron M; Witteman, Holly O; Solomon, Jacob B; Exe, Nicole L; Fagerlin, Angela

2018-03-26

Patient-facing displays of laboratory test results typically provide patients with one reference point (the "standard range"). To test the effect of including an additional harm anchor reference point in visual displays of laboratory test results, which indicates how far outside of the standard range values would need to be in order to suggest substantial patient risk. Using a demographically diverse, online sample, we compared the reactions of 1618 adults in the United States who viewed visual line displays that included both standard range and harm anchor reference points ("Many doctors are not concerned until here") to displays that included either (1) only a standard range, (2) standard range plus evaluative categories (eg, "borderline high"), or (3) a color gradient showing degree of deviation from the standard range. Providing the harm anchor reference point significantly reduced perceived urgency of close-to-normal alanine aminotransferase and creatinine results (P values <.001) but not generally for platelet count results. Notably, display type did not significantly alter perceptions of more extreme results in potentially harmful ranges. Harm anchors also substantially reduced the number of participants who wanted to contact their doctor urgently or go to the hospital about these test results. Presenting patients with evaluative cues regarding when test results become clinically concerning can reduce the perceived urgency of out-of-range results that do not require immediate clinical action. ©Brian J Zikmund-Fisher, Aaron M Scherer, Holly O Witteman, Jacob B Solomon, Nicole L Exe, Angela Fagerlin. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 26.03.2018.

Recent Radiation Test Results for Power MOSFETs

NASA Technical Reports Server (NTRS)

Lauenstein, Jean-Marie; Topper, Alyson D.; Casey, Megan C.; Wilcox, Edward P.; Phan, Anthony M.; Kim, Hak S.; LaBel, Kenneth A.

2013-01-01

Single-event effect (SEE) and total ionizing dose (TID) test results are presented for various hardened and commercial power metal-oxide-semiconductor field effect transistors (MOSFETs), including vertical planar, trench, superjunction, and lateral process designs.

Mesoscale Modeling, Forecasting and Remote Sensing Research.

DTIC Science & Technology

remote sensing , cyclonic scale diagnostic studies and mesoscale numerical modeling and forecasting are summarized. Mechanisms involved in the release of potential instability are discussed and simulated quantitatively, giving particular attention to the convective formulation. The basic mesoscale model is documented including the equations, boundary condition, finite differences and initialization through an idealized frontal zone. Results of tests including a three dimensional test with real data, tests of convective/mesoscale interaction and tests with a detailed

Surprising results: HIV testing and changes in contraceptive practices among young women in Malawi

PubMed Central

Sennott, Christie; Yeatman, Sara

2015-01-01

This study uses eight waves of data from the population-based Tsogolo la Thanzi study (2009–2011) in rural Malawi to examine changes in young women’s contraceptive practices, including the use of condoms, non-barrier contraceptive methods, and abstinence, following positive and negative HIV tests. The analysis factors in women’s prior perceptions of their HIV status that may already be shaping their behaviour and separates surprise HIV test results from those that merely confirm what was already believed. Fixed effects logistic regression models show that HIV testing frequently affects the contraceptive practices of young Malawian women, particularly when the test yields an unexpected result. Specifically, women who are surprised to test HIV positive increase their condom use and are more likely to use condoms consistently. Following an HIV negative test (whether a surprise or expected), women increase their use of condoms and decrease their use of non-barrier contraceptives; the latter may be due to an increase in abstinence following a surprise negative result. Changes in condom use following HIV testing are robust to the inclusion of potential explanatory mechanisms including fertility preferences, relationship status, and the perception that a partner is HIV positive. The results demonstrate that both positive and negative tests can influence women’s sexual and reproductive behaviours, and emphasise the importance of conceptualizing of HIV testing as offering new information only insofar as results deviate from prior perceptions of HIV status. PMID:26160156

Calibration of the Langley 16-foot transonic tunnel with test section air removal

NASA Technical Reports Server (NTRS)

Corson, B. W., Jr.; Runckel, J. F.; Igoe, W. B.

1974-01-01

The Langley 16-foot transonic tunnel with test section air removal (plenum suction) was calibrated to a Mach number of 1.3. The results of the calibration, including the effects of slot shape modifications, test section wall divergence, and water vapor condensation, are presented. A complete description of the wind tunnel and its auxiliary equipment is included.

Development of the Coastal Zone Color Scanner for NIMBUS 7. Volume 2: Test and performance data, revision A

NASA Technical Reports Server (NTRS)

1979-01-01

The results of the Coastal Zone Color Scanner protoflight tests are examined in detail while some of the test results are evaluated with respect to expected performance. Performance characteristics examined include spectral response, signal to noise ratio as a function of radiance input, radiance response, the modulation transfer function, and the field of view and coregistration. The results of orbital sequence tests are also included. The in orbit performance or return of radiometric data in the six spectral bands is evaluated along with the data processing sequence necessary to derive the final data products. Examples of the raw data are given and the housekeeping or diagnostic data which provides information on the day to day health or status of the instrument are discussed.

Central auditory processing disorder (CAPD) tests in a school-age hearing screening programme - analysis of 76,429 children.

PubMed

Skarzynski, Piotr H; Wlodarczyk, Andrzej W; Kochanek, Krzysztof; Pilka, Adam; Jedrzejczak, Wiktor W; Olszewski, Lukasz; Bruski, Lukasz; Niedzielski, Artur; Skarzynski, Henryk

2015-01-01

Hearing disorders among school-age children are a current concern. Continuing studies have been performed in Poland since 2008, and on 2 December 2011 the EU Council adopted Conclusions on the Early Detection and Treatment of Communication Disorders in Children, Including the Use of e-Health Tools and innovative Solutions. The discussion now focuses not only on the efficacy of hearing screening programmes in schoolchildren, but what should be its general aim and what tests it should include? This paper makes the case that it is important to include central auditory processing disorder (CAPD) tests. One such test is the dichotic digits test (DDT). The aim of the presented study was to evaluate the usefulness of the DDT in detecting central hearing disorders in school-age children. During hearing screening programmes conducted in Poland in 2008-2010, exactly 235,664 children (7-12-years-old) were screened in 9,325 schools. Of this number, 7,642 were examined using the DDT test for CAPD. Screening programmes were conducted using the Sense Examination Platform. With the cut-off criterion set at the 5th percentile, results for the DDT applied in a divided attention mode were 11.4% positive for 7-year-olds and 11.3% for 12-year-olds. In the focused attention mode, the comparable result for 12-year-olds was 9.7%. There was a clear right ear advantage. In children with positive DDT results, a higher incidence of other disorders, such as dyslexia, was observed. A test for CAPD should be included in the hearing screening of school-age children. The results of this study form the basis for developing Polish standards in this area.

Calibration and validation of a spar-type floating offshore wind turbine model using the FAST dynamic simulation tool

DOE PAGES

Browning, J. R.; Jonkman, J.; Robertson, A.; ...

2014-12-16

In this study, high-quality computer simulations are required when designing floating wind turbines because of the complex dynamic responses that are inherent with a high number of degrees of freedom and variable metocean conditions. In 2007, the FAST wind turbine simulation tool, developed and maintained by the U.S. Department of Energy's (DOE's) National Renewable Energy Laboratory (NREL), was expanded to include capabilities that are suitable for modeling floating offshore wind turbines. In an effort to validate FAST and other offshore wind energy modeling tools, DOE funded the DeepCwind project that tested three prototype floating wind turbines at 1/50 th scalemore » in a wave basin, including a semisubmersible, a tension-leg platform, and a spar buoy. This paper describes the use of the results of the spar wave basin tests to calibrate and validate the FAST offshore floating simulation tool, and presents some initial results of simulated dynamic responses of the spar to several combinations of wind and sea states. Wave basin tests with the spar attached to a scale model of the NREL 5-megawatt reference wind turbine were performed at the Maritime Research Institute Netherlands under the DeepCwind project. This project included free-decay tests, tests with steady or turbulent wind and still water (both periodic and irregular waves with no wind), and combined wind/wave tests. The resulting data from the 1/50th model was scaled using Froude scaling to full size and used to calibrate and validate a full-size simulated model in FAST. Results of the model calibration and validation include successes, subtleties, and limitations of both wave basin testing and FAST modeling capabilities.« less

Results of design studies and wind tunnel tests of an advanced high lift system for an Energy Efficient Transport

NASA Technical Reports Server (NTRS)

Oliver, W. R.

1980-01-01

The development of an advanced technology high lift system for an energy efficient transport incorporating a high aspect ratio supercritical wing is described. This development is based on the results of trade studies to select the high lift system, analysis techniques utilized to design the high lift system, and results of a wind tunnel test program. The program included the first experimental low speed, high Reynolds number wind tunnel test for this class of aircraft. The experimental results include the effects on low speed aerodynamic characteristics of various leading and trailing edge devices, nacelles and pylons, aileron, spoilers, and Mach and Reynolds numbers. Results are discussed and compared with the experimental data and the various aerodynamic characteristics are estimated.

Manual of Scaling Methods

NASA Technical Reports Server (NTRS)

Bond, Thomas H. (Technical Monitor); Anderson, David N.

2004-01-01

This manual reviews the derivation of the similitude relationships believed to be important to ice accretion and examines ice-accretion data to evaluate their importance. Both size scaling and test-condition scaling methods employing the resulting similarity parameters are described, and experimental icing tests performed to evaluate scaling methods are reviewed with results. The material included applies primarily to unprotected, unswept geometries, but some discussion of how to approach other situations is included as well. The studies given here and scaling methods considered are applicable only to Appendix-C icing conditions. Nearly all of the experimental results presented have been obtained in sea-level tunnels. Recommendations are given regarding which scaling methods to use for both size scaling and test-condition scaling, and icing test results are described to support those recommendations. Facility limitations and size-scaling restrictions are discussed. Finally, appendices summarize the air, water and ice properties used in NASA scaling studies, give expressions for each of the similarity parameters used and provide sample calculations for the size-scaling and test-condition scaling methods advocated.

Avco Lycoming QCGAT program design cycle, demonstrated performance and emissions

NASA Technical Reports Server (NTRS)

Fogel, P.; Koschier, A.

1980-01-01

A high bypass ratio, twin spool turbofan engine of modular design which incorporates a front fan module driven by a modified LTS101 core engine was tested. The engine is housed in a nacelle incorporating full length fan ducting with sound treatment in both the inlet and fan discharge flow paths. Design goals of components and results of component tests are presented together with full engine test results. The rationale behind the combustor design selected for the engine is presented as well as the emissions test results. Total system (engine and nacelle) test results are included.

SU-F-T-313: Clinical Results of a New Customer Acceptance Test for Elekta VMAT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rusk, B; Fontenot, J

Purpose: To report the results of a customer acceptance test (CAT) for VMAT treatments for two matched Elekta linear accelerators. Methods: The CAT tests were performed on two clinically matched Elekta linear accelerators equipped with a 160-leaf MLC. Functional tests included performance checks of the control system during dynamic movements of the diaphragms, MLC, and gantry. Dosimetric tests included MLC picket fence tests at static and variable dose rates and a diaphragm alignment test, all performed using the on-board EPID. Additionally, beam symmetry during arc delivery was measured at the four cardinal angles for high and low dose rate modesmore » using a 2D detector array. Results of the dosimetric tests were analyzed using the VMAT CAT analysis tool. Results: Linear accelerator 1 (LN1) met all stated CAT tolerances. Linear accelerator 2 (LN2) passed the geometric, beam symmetry, and MLC position error tests but failed the relative dose average test for the diaphragm abutment and all three picket fence fields. Though peak doses in the abutment regions were consistent, the average dose was below the stated tolerance corresponding to a leaf junction that was too narrow. Despite this, no significant differences in patient specific VMAT quality assurance measured were observed between the accelerators and both passed monthly MLC quality assurance performed with the Hancock test. Conclusion: Results from the CAT showed LN2 with relative dose averages in the abutment regions of the diaphragm and MLC tests outside the tolerances resulting from differences in leaf gap distances. Tolerances of the dose average tests from the CAT may be small enough to detect MLC errors which do not significantly affect patient QA or the routine MLC tests.« less

The general public's understanding and perception of direct-to-consumer genetic test results.

PubMed

Leighton, J W; Valverde, K; Bernhardt, B A

2012-01-01

Direct-to-consumer (DTC) genetic testing allows consumers to discover their risk for common complex disorders. The extent to which consumers understand typical results provided by DTC genetic testing is currently unknown. Misunderstanding of the results could lead to negative consequences including unnecessary concern, false reassurance or unwarranted changes in screening behaviors. We conducted a study to investigate consumers' perceptions and understanding of DTC test results. An online survey was posted on Facebook that included questions relating to 4 sample test results for risk of developing colorectal cancer, heart disease and skin cancer. Genetic counselors were used as a comparison group. 145 individuals from the general public and 171 genetic counselors completed the survey. A significant difference was found between the way the general public and genetic counselors interpreted the meaning of the DTC results. The general public respondents also believed that results in all 4 scenarios would be significantly more helpful than the genetic counselors did. Although the majority of general public respondents rated the results as easy to understand, they often misinterpreted them. These findings imply that the general public has the potential to misinterpret DTC results without appropriate assistance. Further research is needed to explore optimal methods of providing DTC test results and ways to minimize the risk of negative consequences for consumers. Copyright © 2011 S. Karger AG, Basel.

Estimating the positive predictive value of opportunistic population testing for gonorrhoea as part of the English Chlamydia Screening Programme.

PubMed

Fowler, T; Edeghere, O; Inglis, N; Bradshaw, S

2013-03-01

Advances in technology have raised the possibility of including gonorrhoea testing as part of chlamydia screening. In England this is recommended only where the positive predictive value (PPV) of the test is ≥90%. This study assessed the PPV for gonorrhoea testing using routine testing data. Routine data (including gonorrhoea testing) from the Greater Manchester Chlamydia Screening Programme (GMCSP) in 2009/2010, were used to estimate the PPV for gonorrhoea testing. Of those screened, 0.3% (59/18044) of men and 0.4% (174/41873) of women tested positive for gonorrhoea. The PPV was 82.3% in women and 73.6% in men, in those who also tested positive for chlamydia. For women and men testing negative for chlamydia the PPV for a positive gonorrhoea test was incalculable. The low PPV observed in most groups suggests that where population testing for gonorrhoea occurs there is a need for further confirmatory testing of positive results before treatment decisions are made. Clinicians should be aware of screening test result limitations in this context.

Annual Certification Data for Vehicles and Engines

EPA Pesticide Factsheets

The Annual Certification Test Results Report (often referred to as Federal Register Test Results Report) includes light-duty vehicle and heavy-duty engine reports of projected emission levels at the end of the useful life of a vehicle.

Comparison of aerodynamic coefficients obtained from theoretical calculations wind tunnel tests and flight tests data reduction for the alpha jet aircraft

NASA Technical Reports Server (NTRS)

Guiot, R.; Wunnenberg, H.

1980-01-01

The methods by which aerodynamic coefficients are determined and discussed. These include: calculations, wind tunnel experiments and experiments in flight for various prototypes of the Alpha Jet. A comparison of obtained results shows good correlation between expectations and in-flight test results.

Verification and benchmark testing of the NUFT computer code

NASA Astrophysics Data System (ADS)

Lee, K. H.; Nitao, J. J.; Kulshrestha, A.

1993-10-01

This interim report presents results of work completed in the ongoing verification and benchmark testing of the NUFT (Nonisothermal Unsaturated-saturated Flow and Transport) computer code. NUFT is a suite of multiphase, multicomponent models for numerical solution of thermal and isothermal flow and transport in porous media, with application to subsurface contaminant transport problems. The code simulates the coupled transport of heat, fluids, and chemical components, including volatile organic compounds. Grid systems may be cartesian or cylindrical, with one-, two-, or fully three-dimensional configurations possible. In this initial phase of testing, the NUFT code was used to solve seven one-dimensional unsaturated flow and heat transfer problems. Three verification and four benchmarking problems were solved. In the verification testing, excellent agreement was observed between NUFT results and the analytical or quasianalytical solutions. In the benchmark testing, results of code intercomparison were very satisfactory. From these testing results, it is concluded that the NUFT code is ready for application to field and laboratory problems similar to those addressed here. Multidimensional problems, including those dealing with chemical transport, will be addressed in a subsequent report.

Evaluating performance in sweat testing in medical biochemistry laboratories in Croatia.

PubMed

Aralica, Merica; Krleza, Jasna Lenicek

2017-02-15

Sweat test has a diagnostic role in evaluation of cystic fibrosis. Its performance includes sweat stimulation, collection and analysis. All listed may be sources of inconsistencies in everyday practice. The aim of this study was an evaluation of external quality assessment (EQA) of sweat chloride measurement including sweat test performance in medical biochemistry laboratories in Croatia. EQA for sweat chloride measurement was provided by Croatian Centre for Quality Assessment in Laboratory Medicine (CROQALM) in five consecutive exercises to medical biochemistry laboratories (MBL) that offered sweat testing. A questionnaire regarding all phases of testing was mailed to involved MBL (N = 10). Survey results were compared to current guidelines for sweat test performance. Reported results of EQA in 2015 exercises showed coefficients of variation (CV) from 28.9%, 29.0% to 35.3%, respectively. An introduction of uniform sweat chloride measurement protocol resulted in CV of 15.5% and 14.7% reported in following two exercises in 2016. All MBL included in this study replied to the questionnaire. Results reported by MBL indicated: lack of patient information policy (7/10), use of unacceptable electrodes (6/9), misuse of minimum of acceptable sweat weight (6/9), lack of internal quality assessment (5/9) and recommended reference ranges (5/9 and 4/9). Agreements to guidelines were found in approach to unsuitable patients (9/10) and sweat collection (8/9). Presented results indicate major weak points of current practice in sweat test performance in Croatian MBL and stress the need for its standardization on a national level.

First Human Testing of the Orion Atmosphere Revitalization Technology

NASA Technical Reports Server (NTRS)

Lin, Amy; Sweterlitsch, Jeffrey

2009-01-01

An amine-based carbon dioxide (CO2) and water vapor sorbent in pressure-swing regenerable beds has been developed by Hamilton Sundstrand and baselined for the Orion Atmosphere Revitalization System (ARS). In two previous years at this conference, reports were presented on extensive Johnson Space Center (JSC) testing of the technology in a representative environment with simulated human metabolic loads. The next step in developmental testing at JSC was to replace the simulated humans with real humans; this testing was conducted in the spring of 2008. This first instance of human testing of a new Orion ARS technology included several cases in a sealed Orion-equivalent free volume and three cases using emergency breathing masks connected directly to the ARS loop. Significant test results presented in this paper include comparisons between the standard metabolic rates for CO2 and water vapor production published in Orion requirements documents and real-world rate ranges observed with human test subjects. Also included are qualitative assessments of process flow rate and closed-loop pressure-cycling tolerability while using the emergency masks. Recommendations for modifications to the Orion ARS design and operation, based on the test results, conclude the paper.

First Human Testing of the Orion Atmosphere Revitalization Technology

NASA Technical Reports Server (NTRS)

Lin, Amy; Sweterlitsch, Jeffrey

2008-01-01

An amine-based carbon dioxide (CO2) and water vapor sorbent in pressure-swing regenerable beds has been developed by Hamilton Sundstrand and baselined for the Orion Atmosphere Revitalization System (ARS). In two previous years at this conference, reports were presented on extensive Johnson Space Center (JSC) testing of the technology in a representative environment with simulated human metabolic loads. The next step in developmental testing at JSC was to replace the simulated humans with real humans; this testing was conducted in the spring of 2008. This first instance of human testing of a new Orion ARS technology included several cases in a sealed Orione-quivalent free volume and three cases using emergency breathing masks connected directly to the ARS loop. Significant test results presented in this paper include comparisons between the standard metabolic rates for CO2 and water vapor production published in Orion requirements documents and real-world rate ranges observed with human test subjects. Also included are qualitative assessments of process flow rate and closed-loop pressure-cycling tolerability while using the emergency masks. Recommendations for modifications to the Orion ARS design and operation, based on the test results, conclude the paper.

CALiPER Report 24: OLED Luminaires

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, N. J.; Leon, F. A.; Davis, J. L.

2017-08-01

This report documents an initial investigation of OLED luminaires and summarizes the key features of those products. In addition to photometric testing of four commercial products in independent laboratories, PNNL examined many of the products through teardown testing (disassemblies to identify parts and functionality) in PNNL laboratories. Results of these tests as well as results of stress testing of several OLED luminaires at RTI International have been included.

The NASA super pressure balloon - A path to flight

NASA Astrophysics Data System (ADS)

Cathey, H. M.

2009-07-01

The National Aeronautics and Space Administration's Balloon Program Office has invested significant time and effort in extensive ground testing of model super pressure balloons. The testing path has been developed as an outgrowth of the results of the super pressure balloon test flight in 2006. Summary results of the June 2006 super pressure test flight from Kiruna, Sweden are presented including the balloon performance and "lessons learned". This balloons flight performance exceeded expectations, but did not fully deploy. The flight was safely terminated by command. The results of this test flight refocused the project's efforts toward additional ground testing and analysis; a path to flight. A series of small 4 m diameter models were made and tested to further explore the deployment and structural capabilities of the balloons and materials. A series of ˜27 m model balloons were successfully tested indoors. These balloons successfully replicated the cleft seen in the Sweden flight, explored the deployment trade space to help characterize better design approaches, and demonstrated an acceptable fix to the deployment issue. Photogrammetry was employed during these ˜27 m model tests to help characterize both the balloon and gore shape evolution under pressurization. A ˜8.5 m ground model was used to explore the design and materials performance. Results of these tests will be presented. A general overview of some of the other project advancements made related to demonstrating the strain arresting nature of the proposed design, materials and analysis work will also be presented. All of this work has prepared a clear path toward a renewed round of test flights. This paper will give an overview of the development approach pursued for this super pressure balloon development. A description of the balloon design, including the modifications made as a result of the lessons learned, is presented. A short deployment test flight of the National Aeronautics and Space Administration's super pressure balloon took place in June 2008. This flight was from Ft. Sumner, New Mexico. Preliminary results of this flight are presented. Future plans for both ground testing and additional test flights are also presented. Goals of the future test flights, which are staged in increments of increasing suspended load and altitude, are presented. This includes the projected balloon volumes, payload capabilities, test flight locations, and proposed flight schedule.

S-2 stage 1/25 scale model base region thermal environment test. Volume 1: Test results, comparison with theory and flight data

NASA Technical Reports Server (NTRS)

Sadunas, J. A.; French, E. P.; Sexton, H.

1973-01-01

A 1/25 scale model S-2 stage base region thermal environment test is presented. Analytical results are included which reflect the effect of engine operating conditions, model scale, turbo-pump exhaust gas injection on base region thermal environment. Comparisons are made between full scale flight data, model test data, and analytical results. The report is prepared in two volumes. The description of analytical predictions and comparisons with flight data are presented. Tabulation of the test data is provided.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Geoffrey Wayne; Leonard, Philip; Hartline, Ernest Leon

High Explosives and Technology (M-7) completed the second round of formulation and testing of Remediated Nitrate Salt (RNS) surrogates on March 17, 2016. This report summarizes the results of the work and also includes additional documentation required under test plan PLAN-TA9-2443 Rev B, "Remediated Nitrate Salt (RNS) Surrogate Formulation and Testing Standard Procedure", released February 16, 2016. All formulation and testing was carried out according to PLAN-TA9-2443 Rev B. Results from the first round of formulation and testing were documented in memorandum M7-16-6042, "Results from First Round of Remediated Nitrate Salt Surrogate Formulation and Testing."

NASA's Evolutionary Xenon Thruster (NEXT) Prototype Model 1R (PM1R) Ion Thruster and Propellant Management System Wear Test Results

NASA Technical Reports Server (NTRS)

VanNoord, Jonathan L.; Soulas, George C.; Sovey, James S.

2010-01-01

The results of the NEXT wear test are presented. This test was conducted with a 36-cm ion engine (designated PM1R) and an engineering model propellant management system. The thruster operated with beam extraction for a total of 1680 hr and processed 30.5 kg of xenon during the wear test, which included performance testing and some operation with an engineering model power processing unit. A total of 1312 hr was accumulated at full power, 277 hr at low power, and the remainder was at intermediate throttle levels. Overall ion engine performance, which includes thrust, thruster input power, specific impulse, and thrust efficiency, was steady with no indications of performance degradation. The propellant management system performed without incident during the wear test. The ion engine and propellant management system were also inspected following the test with no indication of anomalous hardware degradation from operation.

Genetic susceptibility testing for neurodegenerative diseases: ethical and practice issues.

PubMed

Roberts, J Scott; Uhlmann, Wendy R

2013-11-01

As the genetics of neurodegenerative disease become better understood, opportunities for genetic susceptibility testing for at-risk individuals will increase. Such testing raises important ethical and practice issues related to test access, informed consent, risk estimation and communication, return of results, and policies to prevent genetic discrimination. The advent of direct-to-consumer genetic susceptibility testing for various neurodegenerative disorders (including Alzheimer's disease (AD), Parkinson's disease, and certain prion diseases) means that ethical and practical challenges must be faced not only in traditional research and clinical settings, but also in broader society. This review addresses several topics relevant to the development and implementation of genetic susceptibility tests across research, clinical, and consumer settings; these include appropriate indications for testing, the implications of different methods for disclosing test results, clinical versus personal utility of risk information, psychological and behavioral responses to test results, testing of minors, genetic discrimination, and ethical dilemmas posed by whole-genome sequencing. We also identify future areas of likely growth in the field, including pharmacogenomics and genetic screening for individuals considering or engaged in activities that pose elevated risk of brain injury (e.g., football players, military personnel). APOE gene testing for risk of Alzheimer's disease is used throughout as an instructive case example, drawing upon the authors' experience as investigators in a series of multisite randomized clinical trials that have examined the impact of disclosing APOE genotype status to interested individuals (e.g., first-degree relatives of AD patients, persons with mild cognitive impairment). Copyright © 2013 Elsevier Ltd. All rights reserved.

Promoting clinical and laboratory interaction by harmonization.

PubMed

Plebani, Mario; Panteghini, Mauro

2014-05-15

The lack of interchangeable results in current practice among clinical laboratories has underpinned greater attention to standardization and harmonization projects. Although the focus was mainly on the standardization and harmonization of measurement procedures and their results, the scope of harmonization goes beyond method and analytical results: it includes all other aspects of laboratory testing, including terminology and units, report formats, reference limits and decision thresholds, as well as test profiles and criteria for the interpretation of results. In particular, as evidence collected in last decades demonstrates that pre-pre- and post-post-analytical steps are more vulnerable to errors, harmonization initiatives should be performed to improve procedures and processes at the laboratory-clinical interface. Managing upstream demand, down-stream interpretation of laboratory results, and subsequent appropriate action through close relationships between laboratorians and clinicians remains a crucial issue of the laboratory testing process. Therefore, initiatives to improve test demand management from one hand and to harmonize procedures to improve physicians' acknowledgment of laboratory data and their interpretation from the other hand are needed in order to assure quality and safety in the total testing process. © 2013.

Maternal Plasma DNA and RNA Sequencing for Prenatal Testing.

PubMed

Tamminga, Saskia; van Maarle, Merel; Henneman, Lidewij; Oudejans, Cees B M; Cornel, Martina C; Sistermans, Erik A

2016-01-01

Cell-free DNA (cfDNA) testing has recently become indispensable in diagnostic testing and screening. In the prenatal setting, this type of testing is often called noninvasive prenatal testing (NIPT). With a number of techniques, using either next-generation sequencing or single nucleotide polymorphism-based approaches, fetal cfDNA in maternal plasma can be analyzed to screen for rhesus D genotype, common chromosomal aneuploidies, and increasingly for testing other conditions, including monogenic disorders. With regard to screening for common aneuploidies, challenges arise when implementing NIPT in current prenatal settings. Depending on the method used (targeted or nontargeted), chromosomal anomalies other than trisomy 21, 18, or 13 can be detected, either of fetal or maternal origin, also referred to as unsolicited or incidental findings. For various biological reasons, there is a small chance of having either a false-positive or false-negative NIPT result, or no result, also referred to as a "no-call." Both pre- and posttest counseling for NIPT should include discussing potential discrepancies. Since NIPT remains a screening test, a positive NIPT result should be confirmed by invasive diagnostic testing (either by chorionic villus biopsy or by amniocentesis). As the scope of NIPT is widening, professional guidelines need to discuss the ethics of what to offer and how to offer. In this review, we discuss the current biochemical, clinical, and ethical challenges of cfDNA testing in the prenatal setting and its future perspectives including novel applications that target RNA instead of DNA. © 2016 Elsevier Inc. All rights reserved.

Stereo tests as a screening tool for strabismus: which is the best choice?

PubMed Central

Ancona, Chiara; Stoppani, Monica; Odazio, Veronica; La Spina, Carlo; Corradetti, Giulia; Bandello, Francesco

2014-01-01

Purpose To compare four stereo tests (Lang I, Lang II, Titmus, and TNO) and assess their effectiveness. The main focus of this study is to identify the most useful stereo test as a challenging tool in the screening of strabismus. Patients and methods A total of 143 Caucasian subjects, 74 males (52%) and 69 females (48%), aged between 4 years and 78 years (mean age 19.09±15.12 years) were examined at our Strabismus Service (Scientific Institute San Raffaele Hospital, Milan, Italy) and included in this observational cross-sectional study. Subjects recruited in this study were either affected by strabismus, including microstrabismic patients, or healthy volunteers. Subjects affected by ophthalmological diseases, other than strabismus, were excluded. All patients underwent both ophthalmological and orthoptic examination, including stereo tests, Hirschberg Corneal Light Reflex Test, Worth Four-Dot Test, the 4 Prism Diopter Base-Out Test, Cover Testing, Bruckner Test, visual acuity, automated refraction under 1% tropicamide cycloplegia and thereafter, posterior pole evaluation. Results All data were processed using the IBM SPSS Statistics, Version 2.0, to perform all statistical calculations. The main finding of this study is that Lang I stereo test achieved the highest sensitivity (89.8%) and specificity (95.2%) in detecting strabismus, including microstrabismus as well, compared to all the other stereoacuity tests. Furthermore, Lang I is the stereo test with the highest positive predictive value and negative predictive value, both greater than 90%. Conclusion The stereo test with the highest sensitivity, specificity, positive predictive value, and negative predictive value is Lang I. These results suggest its applicability as a screening test for strabismus in people older than 4 years. PMID:25419114

Optical fiber dispersion characterization study

NASA Technical Reports Server (NTRS)

Geeslin, A.; Arriad, A.; Riad, S. M.; Padgett, M. E.

1979-01-01

The theory, design, and results of optical fiber pulse dispersion measurements are considered. Both the hardware and software required to perform this type of measurement are described. Hardware includes a thermoelectrically cooled injection laser diode source, an 800 GHz gain bandwidth produce avalanche photodiode and an input mode scrambler. Software for a HP 9825 computer includes fast Fourier transform, inverse Fourier transform, and optimal compensation deconvolution. Test set construction details are also included. Test results include data collected on a 1 Km fiber, a 4 Km fiber, a fused spliced, eight 600 meter length fibers concatenated to form 4.8 Km, and up to nine optical connectors.

42 CFR 493.1251 - Standard: Procedure manual.

Code of Federal Regulations, 2013 CFR

2013-10-01

... (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Quality System for Nonwaived Testing Analytic... intervals (normal values). (11) Imminently life-threatening test results, or panic or alert values. (12... reporting patient results including, when appropriate, the protocol for reporting imminently life...

42 CFR 493.1251 - Standard: Procedure manual.

Code of Federal Regulations, 2014 CFR

2014-10-01

... (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Quality System for Nonwaived Testing Analytic... intervals (normal values). (11) Imminently life-threatening test results, or panic or alert values. (12... reporting patient results including, when appropriate, the protocol for reporting imminently life...

42 CFR 493.1251 - Standard: Procedure manual.

Code of Federal Regulations, 2010 CFR

2010-10-01

... (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Quality System for Nonwaived Testing Analytic... intervals (normal values). (11) Imminently life-threatening test results, or panic or alert values. (12... reporting patient results including, when appropriate, the protocol for reporting imminently life...

Test Results of the Modified Space Shuttle Main Engine at the Marshall Space Flight Center Technology Test Bed Facility

NASA Technical Reports Server (NTRS)

Cook, J.; Dumbacher, D.; Ise, M.; Singer, C.

1990-01-01

A modified space shuttle main engine (SSME), which primarily includes an enlarged throat main combustion chamber with the acoustic cavities removed and a main injector with the stability control baffles removed, was tested. This one-of-a-kind engine's design changes are being evaluated for potential incorporation in the shuttle flight program in the mid-1990's. Engine testing was initiated on September 15, 1988 and has accumulated 1,915 seconds and 19 starts. Testing is being conducted to characterize the engine system performance, combustion stability with the baffle-less injector, and both low pressure oxidizer turbopump (LPOTP) and high pressure oxidizer turbopump (HPOTP) for suction performance. These test results are summarized and compared with the SSME flight configuration data base. Testing of this new generation SSME is the first product from the technology test bed (TTB). Figure test plans for the TTB include the highly instrumented flight configuration SSME and advanced liquid propulsion technology items.

Thermosyphon Flooding in Reduced Gravity Environments Test Results

NASA Technical Reports Server (NTRS)

Gibson, Marc A.; Jaworske, Donald A.; Sanzi, Jim; Ljubanovic, Damir

2013-01-01

The condenser flooding phenomenon associated with gravity aided two-phase thermosyphons was studied using parabolic flights to obtain the desired reduced gravity environment (RGE). The experiment was designed and built to test a total of twelve titanium water thermosyphons in multiple gravity environments with the goal of developing a model that would accurately explain the correlation between gravitational forces and the maximum axial heat transfer limit associated with condenser flooding. Results from laboratory testing and parabolic flights are included in this report as part I of a two part series. The data analysis and correlations are included in a follow on paper.

Production development of organic nonflammable spacecraft potting, encapsulating and conformal coating compounds. Volume 3: Appendices

NASA Technical Reports Server (NTRS)

Lieberman, S. L.

1974-01-01

Appendices are presented which include: statement of work; material vendor contacts; formulation/processing data sheet; upward propagation test; flammability test conditions/results sheet; odor test; vacuum stability requirements; flammability test facility; determination of offgassing products and carbon monoxide test; and pneumatic and mechanical impact test guidelines.

40 CFR 85.2223 - On-board diagnostic test report.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 18 2010-07-01 2010-07-01 false On-board diagnostic test report. 85... Tests § 85.2223 On-board diagnostic test report. (a) Motorists whose vehicles fail the on-board diagnostic test described in § 85.2222 shall be provided with the on-board diagnostic test results, including...

40 CFR 85.2223 - On-board diagnostic test report.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 18 2011-07-01 2011-07-01 false On-board diagnostic test report. 85... Tests § 85.2223 On-board diagnostic test report. (a) Motorists whose vehicles fail the on-board diagnostic test described in § 85.2222 shall be provided with the on-board diagnostic test results, including...

Battleship tank firing test of H-II launch vehicle - First stage

NASA Astrophysics Data System (ADS)

Watanabe, Atsutaro; Endo, Mamoru; Yamazaki, Isao; Maemura, Takashi; Namikawa, Tatsuo

1991-06-01

The H-II launch vehicle capable of placing 2-ton-class payloads on geostationary orbits is outlined, and focus is placed on its propulsion system. The development status of the project, including component development, preliminary battleship tank firing test (BFT-1), battleship tank firing test (BFT-2), and flight-type tank firing test (CFT) is discussed. The configuration and schematic diagram of BFT-2 are presented, and the firing test results of BFT-2 first series are analyzed, including engine performance, interface compatibility, and pressurization of subsystems.

Proposed Interventions to Decrease the Frequency of Missed Test Results

ERIC Educational Resources Information Center

Wahls, Terry L.; Cram, Peter

2009-01-01

Numerous studies have identified that delays in diagnosis related to the mishandling of abnormal test results are an import contributor to diagnostic errors. Factors contributing to missed results included organizational factors, provider factors and patient-related factors. At the diagnosis error conference continuing medical education conference…

Intermediate-Size Inducer Pump design report. [LMFBR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boardman, T.J.

1979-06-15

This report summarizes the mechanical, structural, and hydrodynamic design of the Intermediate-Size Inducer Pump (ISIP). The design was performed under Atomics International's DOE Base Technology Program by the Atomics International and Rocketdyne Divisions of Rockwell International. The pump was designed to utilize the FFTF prototype pump frame as a test vehicle to test the inducer, impeller, and diffuser plus necessary adapter hardware under simulated Large Scale Liquid Metal Fast Breeder Reactor service conditions. The report describes the design requirements including the purpose and objectives, and discusses those design efforts and considerations made to meet the requirements. Included in the reportmore » are appendices showing calculative methods and results. Also included are overall assembly and layout drawings plus some details used as illustrations for discussion of the design results and the results of water tests performed on a model of the inducer.« less

The NASA atomic oxygen effects test program

NASA Technical Reports Server (NTRS)

Banks, Bruce A.; Rutledge, Sharon K.; Brady, Joyce A.

1988-01-01

The NASA Atomic Oxygen Effects Test Program was established to compare the low earth orbital simulation characteristics of existing atomic oxygen test facilities and utilize the collective data from a multitude of simulation facilities to promote understanding of mechanisms and erosion yield dependence upon energy, flux, metastables, charge, and environmental species. Four materials chosen for this evaluation include Kapton HN polyimide, FEP Teflon, polyethylene, and graphite single crystals. The conditions and results of atomic oxygen exposure of these materials is reported by the participating organizations and then assembled to identify degrees of dependency of erosion yields that may not be observable from any single atomic oxygen low earth orbital simulation facility. To date, the program includes 30 test facilities. Characteristics of the participating test facilities and results to date are reported.

Seal material development test program

NASA Technical Reports Server (NTRS)

1971-01-01

A program designed to characterize an experimental fluoroelastomer material designated AF-E-124D, is examined. Tests conducted include liquid nitrogen load compression tests, flexure tests and valve seal tests, ambient and elevated temperature compression set tests, and cleaning and flushing fluid exposure tests. The results of these tests indicate the AF-E-124D is a good choice for a cryogenic seal, since it exhibits good low temperature sealing characteristics and resistance to permanent set. The status of this material as an experimental fluorelastomer is stressed and recommended. Activity includes definition and control of critical processing to ensure consistent material properties. Design, fabrication and test of this and other materials is recommended in valve and static seal applications.

Test Bias and the Culturally Different Early Adolescent.

ERIC Educational Resources Information Center

Roberts, Eileen; DeBlassie, Richard R.

1983-01-01

Defines test bias as a phenomenon in which test scores result in negative outcomes for certain groups, often lower socioeconomic groups and minorities. Discusses three manifestations of test bias including content, atmosphere, and use bias and presents recommendations for remedying bias problems in testing the culturally different. (JAC)

Long-term stability of amorphous-silicon modules

NASA Technical Reports Server (NTRS)

Ross, R. G., Jr.

1986-01-01

The Jet Propulsion Laboratory (JPL) program of developing qualification tests necessary for amorphous silicon modules, including appropriate accelerated environmental tests reveal degradation due to illumination. Data were given which showed the results of temperature-controlled field tests and accelerated tests in an environmental chamber.

Experimental design, operation, and results of a 4 kW high temperature steam electrolysis experiment

DOE PAGES

Zhang, Xiaoyu; O'Brien, James E.; Tao, Greg; ...

2015-08-06

High temperature steam electrolysis (HTSE) is a promising technology for large-scale hydrogen production. However, research on HTSE performance above the kW level is limited. This paper presents the results of 4 kW HTSE long-term test completed in a multi-kW test facility recently developed at the Idaho National Laboratory (INL). The 4 kW HTSE unit included two solid oxide electrolysis stacks operating in parallel, each of which included 40 electrode-supported planar cells. A current density of 0.41 A/cm2 was used for the long-term operation, resulting in a hydrogen production rate about 25 slpm. A demonstration of 920 hours stable operation wasmore » achieved. The paper also includes detailed descriptions of the piping layout, steam generation and delivery system, test fixture, heat recuperation system, hot zone, instrumentation, and operating conditions. As a result, this successful demonstration of multi-kW scale HTSE unit will help to advance the technology toward near-term commercialization.« less

Electrical Evaluation of RCA MWS5001D Random Access Memory, Volume 5, Appendix D

NASA Technical Reports Server (NTRS)

Klute, A.

1979-01-01

The electrical characterization and qualification test results are presented for the RCA MWS 5001D random access memory. The tests included functional tests, AC and DC parametric tests, AC parametric worst-case pattern selection test, determination of worst-case transition for setup and hold times, and a series of schmoo plots. Average input high current, worst case input high current, output low current, and data setup time are some of the results presented.

Electrical Evaluation of RCA MWS5501D Random Access Memory, Volume 2, Appendix a

NASA Technical Reports Server (NTRS)

Klute, A.

1979-01-01

The electrical characterization and qualification test results are presented for the RCA MWS5001D random access memory. The tests included functional tests, AC and DC parametric tests, AC parametric worst-case pattern selection test, determination of worst-case transition for setup and hold times, and a series of schmoo plots. The address access time, address readout time, the data hold time, and the data setup time are some of the results surveyed.

SDT: The Brazilian Standardization of the Silver Drawing Test of Cognition and Emotion.

ERIC Educational Resources Information Center

Allessandrini, Cristina Dias; Duarte, Jose Luclano Miranda; Bianco, Marisa Fernandes; Dupas, Margarida Azevedo

1998-01-01

The Silver Drawing Test of Cognition and Emotion was standardized for Brazilian children (N=2,000). ANOVA results are presented for age and education groups from early grades on, including distinguishing adult education levels; results are compared for U.S. and Brazilian populations. Growth in test scores, emotional content responses, and…

Differential Item Functioning Analysis for Accommodated versus Nonaccommodated Students

ERIC Educational Resources Information Center

Finch, Holmes; Barton, Karen; Meyer, Patrick

2009-01-01

The No Child Left Behind act resulted in an increased reliance on large-scale standardized tests to assess the progress of individual students as well as schools. In addition, emphasis was placed on including all students in the testing programs as well as those with disabilities. As a result, the role of testing accommodations has become more…

A comparison of the results from intra-pleural and intra-peritoneal studies with those from inhalation and intratracheal tests for the assessment of pulmonary responses to inhalable dusts and fibres.

PubMed

Drummond, Gail; Bevan, Ruth; Harrison, Paul

2016-11-01

The aim of this paper is to compare results from inhalation studies with those from intraperitoneal and intrapleural tests, where available, for a number of fibrous and particulate test materials. The objective is to determine how well intraperitoneal/intrapleural studies predict the pathological responses observed in more standard in vivo studies of pulmonary toxicity, with a particular focus on carcinogenicity. Published toxicity data was obtained for a number of materials including asbestos, wollastonite, MMVFs (including glass fibres, stone wools and RCF), silicon carbide whiskers, potassium octatitanate, quartz, kevlar, polypropylene and titanium dioxide. For some of the fibrous material reviewed, there is conformity between the results of intraperitoneal and inhalation tests such that they are either consistently positive or consistently negative. For the remaining fibrous materials reviewed, intraperitoneal and inhalation tests give different results, with positive results in the intraperitoneal test not being reflected by positive inhalation results. It is suggested that the intraperitoneal test can be used to exonerate a dust or fibre (because if negative in the intraperitoneal test it is extremely unlikely to be positive in either inhalation or intratracheal tests) but should not be used to positively determine that a dust or fibre is carcinogenic by inhalation. We would argue against the use of intraperitoneal tests for human health risk assessment except perhaps for the purpose of exoneration of a material from classification as a carcinogen. Copyright © 2016 Elsevier Inc. All rights reserved.

Lithium-Thionyl Chloride Batteries for the Mars Pathfinder Microrover

NASA Technical Reports Server (NTRS)

Deligiannis, Frank; Frank, Harvey; Staniewicz, R. J.; Willson, John

1996-01-01

A discussion of the power requirements for the Mars Pathfinder Mission is given. Topics include: battery requirements; cell design; battery design; test descriptions and results. A summary of the results is also included.

Understanding Cervical Changes: A Health Guide for Women

Cancer.gov

Explains abnormal Pap test, HPV test, and Pap/HPV cotest results. Treatment and follow-up care for abnormal cervical cancer screening results including ASC-US, AGC, LSIL, ASC-H, HSIL, AIS. Learn about colposcopy, types of biopsies, CIN, and HPV vaccine.

GOES Type III Loop Heat Pipe Life Test Results

NASA Technical Reports Server (NTRS)

Ottenstein, Laura

2011-01-01

The GOES Type III Loop Heat Pipe (LHP) was built as a life test unit for the loop heat pipes on the GOES N-Q series satellites. This propylene LHP was built by Dynatherm Corporation in 2000 and tested continuously for approximately 14 months. It was then put into storage for 3 years. Following the storage period, the LHP was tested at Swales Aerospace to verify that the loop performance hadn t changed. Most test results were consistent with earlier results. At the conclusion of testing at Swales, the LHP was transferred to NASA/GSFC for continued periodic testing. The LHP has been set up for testing in the Thermal Lab at GSFC since 2006. A group of tests consisting of start-ups, power cycles, and a heat transport limit test have been performed every six to nine months since March 2006. Tests results have shown no change in the loop performance over the five years of testing. This presentation will discuss the test hardware, test set-up, and tests performed. Test results to be presented include sample plots from individual tests, along with conductance measurements for all tests performed.

Technical and investigative support for high density digital satellite recording systems

NASA Technical Reports Server (NTRS)

Schultz, R. A.

1982-01-01

Methods and results of examinations and tests conducted on magnetic recording tapes under consideration for a high density digital (HDDR) satellite recording system are described. The examinations and tests investigate the performance of tapes with respect to their physical, magnetic and electrical characteristics. The objective of the tests, the likely significance of typical results, and the importance of the characteristics under investigation to the application are included. Theoretical discussions of measurement methods are provided where appropriate. Methods and results are discussed; the results of some sections are tabulated together to facilitate their comparison. The conclusion of each test section relates the test results to their possible significance and attempts to correlate the results of that section with the results of other tests. Some of the sections analyze sources of error inherent in the measurement methods or relate the value of the information obtained to the objectives of the test or the overall purpose of the project.

Static renewal tests using Anodonta imbecillis (freshwater mussels). Anodonta imbecillis QA test 1, Clinch River-Environmental Restoration Program (CR-ERP)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simbeck, D.J.

1993-12-31

Toxicity testing of split whole sediment samples using juvenile freshwater mussels (Anodonta imbecillis) was conducted by TVA and CR-ERP personnel as part of the CR-ERP biomonitoring study of Clinch River sediments to provide a quality assurance mechanism for test organism quality and overall performance of the test. In addition, testing included procedures comparing daily renewal versus non-renewal of test sediments. Testing of sediment samples collected July 15 from Poplar Creek Miles 6.0 and 5.1 was conducted from July 21--30, 1993. Results from this test showed no toxicity (survival effects) to fresh-water mussels during a 9-day exposure to the sediments. Sidemore » by side testing of sediments with daily sediment renewal and no sediment renewal showed no differences between methods. This may be due to the absence of toxicity in both samples and may not reflect true differences between the two methods for toxic sediment. Attachments to this report include: Chain of custody forms -- originals; Toxicity test bench sheets and statistical analyses; and Ammonia analysis request and results.« less

Heat pipe radiators for space

NASA Technical Reports Server (NTRS)

Sellers, J. P.

1976-01-01

Analysis of the data heat pipe radiator systems tested in both vacuum and ambient environments was continued. The systems included (1) a feasibility VCHP header heat-pipe panel, (2) the same panel reworked to eliminate the VCHP feature and referred to as the feasibility fluid header panel, and (3) an optimized flight-weight fluid header panel termed the 'prototype.' A description of freeze-thaw thermal vacuum tests conducted on the feasibility VCHP was included. In addition, the results of ambient tests made on the feasibility fluid header are presented, including a comparison with analytical results. A thermal model of a fluid header heat pipe radiator was constructed and a computer program written. The program was used to make a comparison of the VCHP and fluid-header concepts for both single and multiple panel applications. The computer program was also employed for a parametric study, including optimum feeder heat pipe spacing, of the prototype fluid header.

Comparison of cost-effectiveness between the quantiFERON-TB Gold-In-Tube and T-Spot tests for screening health-care workers for latent tuberculosis infection.

PubMed

Mukai, Shigeto; Shigemura, Katsumi; Yamamichi, Fukashi; Kitagawa, Koichi; Takami, Nozomi; Nomi, Masashi; Arakawa, Soichi; Fujisawa, Masato

2017-01-01

There are several methods used to screen for latent tuberculosis (TB) infection (LTBI) including the QuantiFERON-TB Gold-in-Tube (QFT-GIT) and T-SPOT-TB (T-SPOT) tests. Many studies have reported the equivalence of these two methods, but it is unclear which of them is more cost effective. We investigated the age and cost issues of these tests in screening for LTBI among health-care workers. One hundred and forty new employees during 2008-2011 in our hospital were screened using the QFT-GIT test, and 140 new employees during 2011-2014 were screened with the T-SPOT test for LTBI. The results of both tests were classified as positive, undetermined (retesting required), or negative. There were six positive results (4.29%), eight undetermined results (5.71%), and 126 negative results (90.0%) with the QFT-GIT test. As for the T-SPOT test, there were eight positive results (5.71%), three undetermined results (2.14%), and 129 negative results (92.1%). Fourteen LTBI employees (6 in QFT-GIT and 8 in T-SPOT) were detected statistically equally using the two methods (P = 0.79). The total costs, including those incurred for retesting, were $7,711.86 (US dollar) and $6,525.42 for the QFT-GIT and T-SPOT tests (cost of one test is $55.08 for QFT-GIT and $46.61 for T-SPOT), respectively. T-SPOT is one of the options for screening for LTBI partly owing to the viewpoint of cost-effectiveness. Further prospective studies need to be considered for a definitive conclusion.

Software interface verifier

NASA Technical Reports Server (NTRS)

Soderstrom, Tomas J.; Krall, Laura A.; Hope, Sharon A.; Zupke, Brian S.

1994-01-01

A Telos study of 40 recent subsystem deliveries into the DSN at JPL found software interface testing to be the single most expensive and error-prone activity, and the study team suggested creating an automated software interface test tool. The resulting Software Interface Verifier (SIV), which was funded by NASA/JPL and created by Telos, employed 92 percent software reuse to quickly create an initial version which incorporated early user feedback. SIV is now successfully used by developers for interface prototyping and unit testing, by test engineers for formal testing, and by end users for non-intrusive data flow tests in the operational environment. Metrics, including cost, are included. Lessons learned include the need for early user training. SIV is ported to many platforms and can be successfully used or tailored by other NASA groups.

42 CFR 37.95 - Specifications for performing spirometry examinations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... examinations must include the following: (1) Pre-test checklist. A short Spirometry Pre-Test Checklist (Form... spirometry examinations electronically with content as specified in § 37.96(b), pre-test screening checklists... spirometry examinations, pre-test checklists, and standardized respiratory assessment results in electronic...

Investigation of reliability attributes and accelerated stress factors on terrestrial solar cells

NASA Technical Reports Server (NTRS)

Prince, J. L.; Lathrop, J. W.

1979-01-01

The results of accelerated stress testing of four different types of silicon terrestrial solar cells are discussed. The accelerated stress tests used included bias-temperature tests, bias-temperature-humidity tests, thermal cycle and thermal shock tests, and power cycle tests. Characterization of the cells was performed before stress testing and at periodic down-times, using electrical measurement, visual inspection, and metal adherence pull tests. Electrical parameters measured included short-circuit current, open circuit voltage, and output power, voltage, and current at the maximum power point. Incorporated in the report are the distributions of the prestress electrical data for all cell types. Data were also obtained on cell series and shunt resistance.

Wave Energy Prize - 1/50th Testing - Float Inc

DOE Data Explorer

Wesley Scharmen

2016-01-15

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for Float Inc. During the testing of its 1/50th-scale device, Float Inc. Berger ABAM was deemed ineligible due to the fact that they brought a device with them to test and did not ship the device by the deadline stipulated in the Wave Energy Prize Rules. Because of this, analysis, results, and judging were not completed for this team/device. This submission included files such as: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents

28,000 Hour Xenon Hollow Cathode LifeTest Results

NASA Technical Reports Server (NTRS)

Sarver-Verhey, Timothy R.

1997-01-01

The International Space Station Plasma Contactor System requires a hollow cathode assembly (HCA) with a lifetime of at least 18,000 hours. Critical components of the HCA include the hollow cathode and electron emitter. A series of hollow cathode wear tests was performed which included a life test operated at the maximum current of the HCA. This test sought to verify the hollow cathode design and contamination control protocols. The life test accumulated 27,800 hours of operation before failing to ignite. The hollow cathode exhibited relatively small changes in operating parameters over the course of the test. This life test is the longest duration test of a high current xenon hollow cathode reported to date.

Strength Testing.

ERIC Educational Resources Information Center

Londeree, Ben R.

1981-01-01

Postural deviations resulting from strength and flexibility imbalances include swayback, scoliosis, and rounded shoulders. Screening tests are one method for identifying strength problems. Tests for the evaluation of postural problems are described, and exercises are presented for the strengthening of muscles. (JN)

Antimicrobial effects of a new therapeutic liquid dentifrice formulation on oral bacteria including odorigenic species.

PubMed

Sreenivasan, P K; Furgang, D; Zhang, Y; DeVizio, W; Fine, D H

2005-03-01

The control of oral malodor is well-recognized in efforts to improve oral health. Antimicrobial formulations can mitigate oral malodor, however, procedures to assess effects on oral bacteria including those implicated in halitosis are unavailable. This investigation examined the antimicrobial effects of a new liquid triclosan/copolymer dentifrice (test) formulation that demonstrated significant inhibition of oral malodor in previous organoleptic clinical studies. Procedures compared antimicrobial effects of the test and control formulations on a range of oral micro-organisms including members implicated in halitosis, substantive antimicrobial effects of formulations with hydroxyapatite as a surrogate for human teeth and ex vivo effects on oral bacteria from human volunteers. With Actinomyces viscosus, as a model system, the test formulation demonstrated a dose-dependent effect. At these concentrations the test formulation provided significant antimicrobial effects on 13 strains of oral bacteria including those implicated in bad breath at selected posttreatment time points. Treatment of hydroxyapatite by the test dentifrice resulted in a significant and substantive antimicrobial effect vs. controls. Oral bacteria from subjects treated ex vivo with the test dentifrice resulted in significant reductions in cultivable oral bacteria and odorigenic bacteria producing hydrogen sulfide. In summary, microbiological methods adapted to study odorigenic bacteria demonstrate the significant antimicrobial effects of the test (triclosan/copolymer) dentifrice with laboratory and clinical strains of oral bacteria implicated in bad breath.

Evaluation of the impact of lime softening waste disposal in ...

EPA Pesticide Factsheets

Drinking water treatment residues (WTR), generated from the lime softening processes, are commonly reused or disposed of in a number of applications; these include use as a soil amendment or a subsurface fill. Recently questions were posed by the Florida regulatory community on whether lime WTR that contained a small percentage of other treatment additives could appropriately be characterized as lime WTR, in terms of its total element content and leachability. A study was done using a broad range of leaching tests, including a framework of tests recently adopted by the United States-Environmental Protection Agency (EPA) and tests that were modified to account for scenario specific conditions, such as the presence of natural organic matter (NOM). The results of these additional leaching tests demonstrated that certain applications, including disposal in a water body with NOM or in placement anaerobic environment, did result in increased leaching of elements such as Fe, and that a site specific assessment should be conducted prior to using WTR in these types of applications. This study illustrates the importance of leaching test selection when attempting to provide an estimation of release in practice. Although leaching tests are just one component in a beneficial use assessment and other factors including aquifer and soil properties play a significant role in the outcome, leaching tests should be tailored to most appropriately represent the scenario or reuse ap

TESTING OF TMR SAND MANTIS FINAL REPORT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krementz, D; William Daugherty, W

2007-06-12

Screening tests of Sand Mantis candidate materials selected for erosion resistance have been completed. The results of this testing identified that over a relatively short period of operation (<1 hour), measurable erosion will occur in each of the candidate zoom tube materials given equal operating exposure. Additionally, this testing has shown that erosion of the rubber discharge hose directly downstream of the vehicle could be expected to limit the service life of the discharge hose. On the basis of these test results, SRNL recommends the following; {lg_bullet} redesign of critical system components (e.g., zoom tube, discharge hose) should be conductedmore » to improve system characteristics relative to erosion and capitalize on the results of this testing, {lg_bullet} continued efforts to deploy the Sand Mantis should include testing to better define and optimize operating parameters, and gain an understanding of system dynamics, {lg_bullet} discontinue wear testing with the selected materials pending redesign of critical system components (1st recommendation) and inclusion of other candidate materials. The final selection of additional candidate materials should be made following design changes, but might include a Stellite alloy or zirconia.« less

Fabrication and verification testing of ETM 30 cm diameter ion thrusters

NASA Technical Reports Server (NTRS)

Collett, C.

1977-01-01

Engineering model designs and acceptance tests are described for the 800 and 900 series 30 cm electron bombardment thrustors. Modifications to the test console for a 1000 hr verification test were made. The 10,000 hr endurance test of the S/N 701 thruster is described, and post test analysis results are included.

SIMS prototype system 3 test results: Engineering analysis

NASA Technical Reports Server (NTRS)

1978-01-01

The results obtained during testing of a closed hydronic drain down solar system designed for space and hot water heating is presented. Data analysis is included which documents the system performance and verifies the suitability of SIMS Prototype System 3 for field installation.

Results and Analysis from Space Suit Joint Torque Testing

NASA Technical Reports Server (NTRS)

Matty, Jennifer

2010-01-01

This joint mobility KC lecture included information from two papers, "A Method for and Issues Associated with the Determination of Space Suit Joint Requirements" and "Results and Analysis from Space Suit Joint Torque Testing," as presented for the International Conference on Environmental Systems in 2009 and 2010, respectively. The first paper discusses historical joint torque testing methodologies and approaches that were tested in 2008 and 2009. The second paper discusses the testing that was completed in 2009 and 2010.

Systems special investigation group

NASA Technical Reports Server (NTRS)

1991-01-01

An interim report concerning the Long Duration Exposure Facility (LDEF) is presented by a Boeing Systems special investigation group (SIG). The SIG activities were divided into five engineering disciplines: electrical, mechanical, optics, thermal, and batteries/solar cells. The responsibilities of the SIG included the following areas: support de-integration at Kennedy Space Center (KSC); testing of hardware at Boeing; review of principal investigator (PI) test plans and test results; support of test activities at PI labs; and collation of all test results into the SIG database.

LDEF electronic systems: Successes, failures, and lessons

NASA Technical Reports Server (NTRS)

Miller, Emmett; Porter, Dave; Smith, Dave; Brooks, Larry; Levorsen, Joe; Mulkey, Owen

1991-01-01

Following the Long Duration Exposure Facility (LDEF) retrieval, the Systems Special Investigation Group (SIG) participated in an extensive series of tests of various electronic systems, including the NASA provided data and initiate systems, and some experiment systems. Overall, these were found to have performed remarkably well, even though most were designed and tested under limited budgets and used at least some nonspace qualified components. However, several anomalies were observed, including a few which resulted in some loss of data. The postflight test program objectives, observations, and lessons learned from these examinations are discussed. All analyses are not yet complete, but observations to date will be summarized, including the Boeing experiment component studies and failure analysis results related to the Interstellar Gas Experiment. Based upon these observations, suggestions for avoiding similar problems on future programs are presented.

BRCA1/2 Test Results Impact Risk Management Attitudes, Intentions and Uptake

PubMed Central

O’Neill, Suzanne C.; Valdimarsdottir, Heiddis B.; DeMarco, Tiffani A.; Peshkin, Beth N.; Graves, Kristi D.; Brown, Karen; Hurley, Karen E.; Isaacs, Claudine; Hecker, Sharon; Schwartz, Marc D.

2011-01-01

BACKGROUND Women who receive positive or uninformative BRCA1/2 test results face a number of decisions about how to manage their cancer risk. The purpose of this study was to prospectively examine the effect of receiving a positive vs. uninformative BRCA1/2 genetic test result on the perceived pros and cons of risk-reducing mastectomy (RRM) and risk-reducing oophorectomy (RRO) and breast cancer screening. We further examined how perceived pros and cons of surgery predict intention for and uptake of surgery. METHODS 308 women (146 positive, 162 uninformative) were included in RRM and breast cancer screening analyses. 276 women were included in RRO analyses. Participants completed questionnaires at pre-disclosure baseline and 1-, 6-and 12-months post-disclosure. We used linear multiple regression to assess whether test result contributed to change in pros and cons and logistic regression to predict intentions and surgery uptake. RESULTS Receipt of a positive BRCA1/2 test result predicted stronger pros for RRM and RRO (Ps < .001), but not perceived cons of RRM and RRO. Pros of surgery predicted RRM and RRO intentions in carriers and RRO intentions in uninformatives. Cons predicted RRM intentions in carriers. Pros and cons predicted carriers’ RRO uptake in the year after testing (Ps < .001). CONCLUSIONS Receipt of BRCA1/2 mutation test results impacts how carriers see the positive aspects of RRO and RRM and their surgical intentions. Both the positive and negative aspects predict uptake of surgery. PMID:20383578

A geochemical examination of humidity cell tests

USGS Publications Warehouse

Maest, Ann; Nordstrom, D. Kirk

2017-01-01

Humidity cell tests (HCTs) are long-term (20 to >300 weeks) leach tests that are considered by some to be the among the most reliable geochemical characterization methods for estimating the leachate quality of mined materials. A number of modifications have been added to the original HCT method, but the interpretation of test results varies widely. We suggest that the HCTs represent an underutilized source of geochemical data, with a year-long test generating approximately 2500 individual chemical data points. The HCT concentration peaks and valleys can be thought of as a “chromatogram” of reactions that may occur in the field, whereby peaks in concentrations are associated with different geochemical processes, including sulfate salt dissolution, sulfide oxidation, and dissolution of rock-forming minerals, some of which can neutralize acid. Some of these reactions occur simultaneously, some do not, and geochemical modeling can be used to help distinguish the dominant processes. Our detailed examination, including speciation and inverse modeling, of HCTs from three projects with different geology and mineralization shows that rapid sulfide oxidation dominates over a limited period of time that starts between 40 and 200 weeks of testing. The applicability of laboratory tests results to predicting field leachate concentrations, loads, or rates of reaction has not been adequately demonstrated, although early flush releases and rapid sulfide oxidation rates in HCTs should have some relevance to field conditions. Knowledge of possible maximum solute concentrations is needed to design effective treatment and mitigation approaches. Early flush and maximum sulfide oxidation results from HCTs should be retained and used in environmental models. Factors that complicate the use of HCTs include: sample representation, time for microbial oxidizers to grow, sample storage before testing, geochemical reactions that add or remove constituents, and the HCT results chosen for use in modeling the environmental performance at mine sites. Improved guidance is needed for more consistent interpretation and use of HCT results that rely on identifying: the geochemical processes; the mineralogy, including secondary mineralogy; the available surface area for reactions; and the influence of hydrologic processes on leachate concentrations in runoff, streams, and groundwater.

Methods Used in Economic Evaluations of Chronic Kidney Disease Testing — A Systematic Review

PubMed Central

Sutton, Andrew J.; Breheny, Katie; Deeks, Jon; Khunti, Kamlesh; Sharpe, Claire; Ottridge, Ryan S.; Stevens, Paul E.; Cockwell, Paul; Kalra, Philp A.; Lamb, Edmund J.

2015-01-01

Background The prevalence of chronic kidney disease (CKD) is high in general populations around the world. Targeted testing and screening for CKD are often conducted to help identify individuals that may benefit from treatment to ameliorate or prevent their disease progression. Aims This systematic review examines the methods used in economic evaluations of testing and screening in CKD, with a particular focus on whether test accuracy has been considered, and how analysis has incorporated issues that may be important to the patient, such as the impact of testing on quality of life and the costs they incur. Methods Articles that described model-based economic evaluations of patient testing interventions focused on CKD were identified through the searching of electronic databases and the hand searching of the bibliographies of the included studies. Results The initial electronic searches identified 2,671 papers of which 21 were included in the final review. Eighteen studies focused on proteinuria, three evaluated glomerular filtration rate testing and one included both tests. The full impact of inaccurate test results was frequently not considered in economic evaluations in this setting as a societal perspective was rarely adopted. The impact of false positive tests on patients in terms of the costs incurred in re-attending for repeat testing, and the anxiety associated with a positive test was almost always overlooked. In one study where the impact of a false positive test on patient quality of life was examined in sensitivity analysis, it had a significant impact on the conclusions drawn from the model. Conclusion Future economic evaluations of kidney function testing should examine testing and monitoring pathways from the perspective of patients, to ensure that issues that are important to patients, such as the possibility of inaccurate test results, are properly considered in the analysis. PMID:26465773

Functionalization of MEMS cantilever beams for interconnect reliability investigation: development practice

NASA Astrophysics Data System (ADS)

Bieniek, T.; Janczyk, G.; Dobrowolski, R.; Wojciechowska, K.; Malinowska, A.; Panas, A.; Nieprzecki, M.; Kłos, H.

2016-11-01

This paper covers research results on development of the cantilevers beams test structures for interconnects reliability and robustness investigation. Presented results include design, modelling, simulation, optimization and finally fabrication stage performed on 4 inch Si wafers using the ITE microfabrication facility. This paper also covers experimental results from the test structures characterization.

Results of Mechanical Testing for Pyroceram(tm) Glass-Ceramic

NASA Technical Reports Server (NTRS)

Choi, Sung R.; Gyekenyesi, John P.

2003-01-01

Mechanical testing for Pyroceram (trademark) 9606 glass-ceramic fabricated by Corning was conducted to determine mechanical properties of the material including slow crack growth.Valid testing was not achieved in tension, compression, and shear testing due to inappropriate test specimen configurations provided and primarily due to the existence of fortified layer( in tension).

Test Anxiety and College Students with Attention Deficit Hyperactivity Disorder

ERIC Educational Resources Information Center

Nelson, Jason M.; Lindstrom, Will; Foels, Patricia A.

2014-01-01

Test anxiety was examined in college students with and without attention deficit hyperactivity disorder (ADHD). Results indicated that, relative to college students without ADHD, college students with ADHD reported higher total test anxiety as well as specific aspects of test anxiety, including worry (i.e., cognitive aspects of test anxiety) and…

The Effect of Font Selection on Student Test Anxiety

ERIC Educational Resources Information Center

Murphy, Peter V.

2014-01-01

The emergence of standards-based curriculums has resulted in an increased frequency of student testing, including high-stakes testing. Of students who take tests, up to 65% may experience test anxiety, which can have negative effects on student outcomes. For this reason, the purpose of this single-group, repeated measures design, quantitative…

Process qualification and testing of LENS deposited AY1E0125 D-bottle brackets.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Atwood, Clinton J.; Smugeresky, John E.; Jew, Michael

2006-11-01

The LENS Qualification team had the goal of performing a process qualification for the Laser Engineered Net Shaping{trademark}(LENS{reg_sign}) process. Process Qualification requires that a part be selected for process demonstration. The AY1E0125 D-Bottle Bracket from the W80-3 was selected for this work. The repeatability of the LENS process was baselined to determine process parameters. Six D-Bottle brackets were deposited using LENS, machined to final dimensions, and tested in comparison to conventionally processed brackets. The tests, taken from ES1E0003, included a mass analysis and structural dynamic testing including free-free and assembly-level modal tests, and Haversine shock tests. The LENS brackets performedmore » with very similar characteristics to the conventionally processed brackets. Based on the results of the testing, it was concluded that the performance of the brackets made them eligible for parallel path testing in subsystem level tests. The testing results and process rigor qualified the LENS process as detailed in EER200638525A.« less

Response of an Impact Test Apparatus for Fall Protective Headgear Testing Using a Hybrid-III Head/Neck Assembly

PubMed Central

Caccese, V.; Ferguson, J.; Lloyd, J.; Edgecomb, M.; Seidi, M.; Hajiaghamemar, M.

2017-01-01

A test method based upon a Hybrid-III head and neck assembly that includes measurement of both linear and angular acceleration is investigated for potential use in impact testing of protective headgear. The test apparatus is based upon a twin wire drop test system modified with the head/neck assembly and associated flyarm components. This study represents a preliminary assessment of the test apparatus for use in the development of protective headgear designed to prevent injury due to falls. By including angular acceleration in the test protocol it becomes possible to assess and intentionally reduce this component of acceleration. Comparisons of standard and reduced durometer necks, various anvils, front, rear, and side drop orientations, and response data on performance of the apparatus are provided. Injury measures summarized for an unprotected drop include maximum linear and angular acceleration, head injury criteria (HIC), rotational injury criteria (RIC), and power rotational head injury criteria (PRHIC). Coefficient of variation for multiple drops ranged from 0.4 to 6.7% for linear acceleration. Angular acceleration recorded in a side drop orientation resulted in highest coefficient of variation of 16.3%. The drop test apparatus results in a reasonably repeatable test method that has potential to be used in studies of headgear designed to reduce head impact injury. PMID:28216804

COMPARATIVE TOXICITY TESTING OF SELECTED BENTHIC AND EPIBENTHIC ORGANISMS FOR THE DEVELOPMENT OF SEDIMENT QUALITY TEST PROTOCOLS

EPA Science Inventory

Sediment contamination has resulted in the need to develop an appropriate suite of toxicity tests to assess ecotoxicological impacts on estuarine ecosystems. Existing Environmental Protection Agency (EPA) protocols recommend a number of test organisms, including amphipods, polych...

NEPP Update of Independent Single Event Upset Field Programmable Gate Array Testing

NASA Technical Reports Server (NTRS)

Berg, Melanie; Label, Kenneth; Campola, Michael; Pellish, Jonathan

2017-01-01

This presentation provides a NASA Electronic Parts and Packaging (NEPP) Program update of independent Single Event Upset (SEU) Field Programmable Gate Array (FPGA) testing including FPGA test guidelines, Microsemi RTG4 heavy-ion results, Xilinx Kintex-UltraScale heavy-ion results, Xilinx UltraScale+ single event effect (SEE) test plans, development of a new methodology for characterizing SEU system response, and NEPP involvement with FPGA security and trust.

The development, design and test of a 66 W/kg (30-W/lb) roll-up solar array

NASA Technical Reports Server (NTRS)

Hasbach, W. A.; Ross, R. G., Jr.

1972-01-01

A program to develop a 250 square foot roll-up solar array with a power-to-weight ratio exceeding 30 watts per pound is described. The system design and fabrication of a full scale engineering development model are discussed. The system and development test program results are presented. Special test equipment and test procedures are included, together with comparisons of experimental and analytical results.

Practical challenges related to point of care testing.

PubMed

Shaw, Julie L V

2016-04-01

Point of care testing (POCT) refers to laboratory testing that occurs near to the patient, often at the patient bedside. POCT can be advantageous in situations requiring rapid turnaround time of test results for clinical decision making. There are many challenges associated with POCT, mainly related to quality assurance. POCT is performed by clinical staff rather than laboratory trained individuals which can lead to errors resulting from a lack of understanding of the importance of quality control and quality assurance practices. POCT is usually more expensive than testing performed in the central laboratory and requires a significant amount of support from the laboratory to ensure the quality testing and meet accreditation requirements. Here, specific challenges related to POCT compliance with accreditation standards are discussed along with strategies that can be used to overcome these challenges. These areas include: documentation of POCT orders, charting of POCT results as well as training and certification of individuals performing POCT. Factors to consider when implementing connectivity between POCT instruments and the electronic medical record are also discussed in detail and include: uni-directional versus bidirectional communication, linking patient demographic information with POCT software, the importance of positive patient identification and considering where to chart POCT results in the electronic medical record.

Computer model to simulate testing at the National Transonic Facility

NASA Technical Reports Server (NTRS)

Mineck, Raymond E.; Owens, Lewis R., Jr.; Wahls, Richard A.; Hannon, Judith A.

1995-01-01

A computer model has been developed to simulate the processes involved in the operation of the National Transonic Facility (NTF), a large cryogenic wind tunnel at the Langley Research Center. The simulation was verified by comparing the simulated results with previously acquired data from three experimental wind tunnel test programs in the NTF. The comparisons suggest that the computer model simulates reasonably well the processes that determine the liquid nitrogen (LN2) consumption, electrical consumption, fan-on time, and the test time required to complete a test plan at the NTF. From these limited comparisons, it appears that the results from the simulation model are generally within about 10 percent of the actual NTF test results. The use of actual data acquisition times in the simulation produced better estimates of the LN2 usage, as expected. Additional comparisons are needed to refine the model constants. The model will typically produce optimistic results since the times and rates included in the model are typically the optimum values. Any deviation from the optimum values will lead to longer times or increased LN2 and electrical consumption for the proposed test plan. Computer code operating instructions and listings of sample input and output files have been included.

Case-finding for hepatitis C in primary care: a mixed-methods service evaluation

PubMed Central

Datta, Shivani; Horwood, Jeremy; Hickman, Matthew; Sharp, Debbie

2014-01-01

Background Hepatitis C is often asymptomatic, presenting with liver failure and cancer decades after infection. People who inject drugs (PWID) and immigrant populations from countries with a moderate-to-high prevalence of hepatitis C virus (HCV) are the main risk groups. Deaths and hospital admissions due to HCV cirrhosis tripled between 1998 and 2010, but the majority of people with chronic HCV are unaware of it. Aim To identify patients at risk of developing hepatitis C using routine GP data, to determine the proportion not tested, and to explore GPs’ views regarding testing. Design and setting Mixed-methods service evaluation (density-based selection of PWID) in six NHS practices in Bristol. Method Patients at risk of HCV were identified. The Health Protection Agency laboratory (now part of Public Health England) provided test results. Semi-structured interviews with 17 GPs were audiorecorded and thematic analyses conducted on anonymised transcripts. Results Of 3765 patients identified as being at risk of developing hepatitis C, 3051 (81%) had no test result, including 53% of PWID and 93% of the ‘ethnicity’ group. All GPs said they usually test PWID. Most GPs test for HIV and hepatitis B in immigrants more often than they test for HCV. Barriers to testing included not questioning patients about risk factors, competing priorities, the chaotic lifestyle of PWID, difficulty extracting information from computerised records, and forgetting to address HCV. Conclusion Computer prompts and GP education on whom to test are warranted. Ensuring that country of origin and drug use is included on the new-patient questionnaire might also aid case-finding for HCV. PMID:24567619

Life Test Results for Water Heat Pipes Operating at 200 °C to 300 °C

NASA Astrophysics Data System (ADS)

Rosenfeld, John H.; Gernert, Nelson J.

2008-01-01

For lunar or planetary bases to be viable, a robust electric generating system will be required for powering the habitat. Water heat pipes offer an attractive solution for lunar base heat rejection, and would serve as a qualification for them on other long duration missions. Successful operation near the upper end of water operating range is a requirement for the application. Results are reported for life tests on water heat pipes that were operated at various temperatures between 200 °C and 300 °C. Tests were conducted on twenty three gravity-assisted water heat pipes. Eleven titanium/water heat pipes and ten Monel/water heat pipes were tested at temperatures above 200 °C. Two cupronickel heat pipes were also assembled and tested. Titanium alloys tested included CP-2 titanium, as well as two beta-titanium alloys, namely 15-3 and Nitinol alloys. Some of the titanium alloy life tests used wicks fabricated from CP-2 titanium screen or porous felt. Monel alloys tested included 400 and K-500 alloys. Some of the Monel heat pipes contained copper/nickel wicks that were fabricated by brazing nickel-plated copper felt metal wicks. Although most of the envelope/material combinations exhibit favorable results at 200 °C, some of the combinations failed at higher temperatures. Causes of failure included stress-creep of envelopes and corrosion at axial or end cap welds. This information represents a significant advance in selection of materials for 200 °C to 300 °C water heat pipes. Life testing work is being continued.

Effects of personal identifier resynthesis on clinical text de-identification.

PubMed

Yeniterzi, Reyyan; Aberdeen, John; Bayer, Samuel; Wellner, Ben; Hirschman, Lynette; Malin, Bradley

2010-01-01

De-identified medical records are critical to biomedical research. Text de-identification software exists, including "resynthesis" components that replace real identifiers with synthetic identifiers. The goal of this research is to evaluate the effectiveness and examine possible bias introduced by resynthesis on de-identification software. We evaluated the open-source MITRE Identification Scrubber Toolkit, which includes a resynthesis capability, with clinical text from Vanderbilt University Medical Center patient records. We investigated four record classes from over 500 patients' files, including laboratory reports, medication orders, discharge summaries and clinical notes. We trained and tested the de-identification tool on real and resynthesized records. We measured performance in terms of precision, recall, F-measure and accuracy for the detection of protected health identifiers as designated by the HIPAA Safe Harbor Rule. The de-identification tool was trained and tested on a collection of real and resynthesized Vanderbilt records. Results for training and testing on the real records were 0.990 accuracy and 0.960 F-measure. The results improved when trained and tested on resynthesized records with 0.998 accuracy and 0.980 F-measure but deteriorated moderately when trained on real records and tested on resynthesized records with 0.989 accuracy 0.862 F-measure. Moreover, the results declined significantly when trained on resynthesized records and tested on real records with 0.942 accuracy and 0.728 F-measure. The de-identification tool achieves high accuracy when training and test sets are homogeneous (ie, both real or resynthesized records). The resynthesis component regularizes the data to make them less "realistic," resulting in loss of performance particularly when training on resynthesized data and testing on real data.

Development and Design Application of Rigidized Surface Insulation Thermal Protection Systems, Volume 1. [for the space shuttle

NASA Technical Reports Server (NTRS)

1972-01-01

Materials and design technology of the all-silica LI-900 rigid surface insulation (RSI) thermal protection system (TPS) concept for the shuttle spacecraft is presented. All results of contract development efforts are documented. Engineering design and analysis of RSI strain arrestor plate material selections, sizing, and weight studies are reported. A shuttle prototype test panel was designed, analyzed, fabricated, and delivered. Thermophysical and mechanical properties of LI-900 were experimentally established and reported. Environmental tests, including simulations of shuttle loads represented by thermal response, turbulent duct, convective cycling, and chemical tolerance tests are described and results reported. Descriptions of material test samples and panels fabricated for testing are included. Descriptions of analytical sizing and design procedures are presented in a manner formulated to allow competent engineering organizations to perform rational design studies. Results of parametric studies involving material and system variables are reported. Material performance and design data are also delineated.

Cryogenic Fluid Storage Technology Development: Recent and Planned Efforts at NASA

NASA Technical Reports Server (NTRS)

Moran, Matthew E.

2009-01-01

Recent technology development work conducted at NASA in the area of Cryogenic Fluid Management (CFM) storage is highlighted, including summary results, key impacts, and ongoing efforts. Thermodynamic vent system (TVS) ground test results are shown for hydrogen, methane, and oxygen. Joule-Thomson (J-T) device tests related to clogging in hydrogen are summarized, along with the absence of clogging in oxygen and methane tests. Confirmation of analytical relations and bonding techniques for broad area cooling (BAC) concepts based on tube-to-tank tests are presented. Results of two-phase lumped-parameter computational fluid dynamic (CFD) models are highlighted, including validation of the model with hydrogen self pressurization test data. These models were used to simulate Altair representative methane and oxygen tanks subjected to 210 days of lunar surface storage. Engineering analysis tools being developed to support system level trades and vehicle propulsion system designs are also cited. Finally, prioritized technology development risks identified for Constellation cryogenic propulsion systems are presented, and future efforts to address those risks are discussed.

2010 Toyota Prius VIN 0462 Hybrid Electric Vehicle Battery Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tyler Gray; Matthew Shirk

2013-01-01

The U.S. Department of Energy Advanced Vehicle Testing Activity Program consists of vehicle, battery, and infrastructure testing on advanced technology related to transportation. The activity includes tests on hybrid electric vehicles (HEVs), including testing the HEV batteries when both the vehicles and batteries are new and at the conclusion of 160,000 miles of on road fleet testing. This report documents battery testing performed for the 2010 Toyota Prius HEV (VIN: JTDKN3DU2A5010462). Battery testing was performed by the Electric Transportation Engineering Corporation dba ECOtality North America. The Idaho National Laboratory and ECOtality North America collaborate on the Advanced Vehicle Testing Activitymore » for the Vehicle Technologies Program of the U.S. Department of Energy.« less

2010 Honda Insight VIN 0141 Hybrid Electric Vehicle Battery Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tyler Gray

2013-01-01

The U.S. Department of Energy Advanced Vehicle Testing Activity Program consists of vehicle, battery, and infrastructure testing on advanced technology related to transportation. The activity includes tests on hybrid electric vehicles (HEVs), including testing the HEV batteries when both the vehicles and batteries are new and at the conclusion of 160,000 miles of on road fleet testing. This report documents battery testing performed for the 2010 Honda Insight HEV (VIN: JHMZE2H78AS010141). Battery testing was performed by the Electric Transportation Engineering Corporation dba ECOtality North America. The Idaho National Laboratory and ECOtality North America collaborate on the Advanced Vehicle Testing Activitymore » for the Vehicle Technologies Program of the U.S. Department of Energy.« less

2010 Toyota Prius VIN 6063 Hybrid Electric Vehicle Battery Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tyler Gray; Matthew Shirk

2013-01-01

The U.S. Department of Energy Advanced Vehicle Testing Activity Program consists of vehicle, battery, and infrastructure testing on advanced technology related to transportation. The activity includes tests on hybrid electric vehicles (HEVs), including testing the HEV batteries when both the vehicles and batteries are new and at the conclusion of 160,000 miles of on road fleet testing. This report documents battery testing performed for the 2010 Toyota Prius HEV (VIN JTDKN3DU5A0006063). Battery testing was performed by the Electric Transportation Engineering Corporation dba ECOtality North America. The Idaho National Laboratory and ECOtality North America collaborate on the Advanced Vehicle Testing Activitymore » for the Vehicle Technologies Program of the U.S. Department of Energy.« less

2010 Honda Insight VIN 1748 Hybrid Electric Vehicle Battery Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tyler Gray; Matthew Shirk

2013-01-01

The U.S. Department of Energy Advanced Vehicle Testing Activity Program consists of vehicle, battery, and infrastructure testing on advanced technology related to transportation. The activity includes tests on hybrid electric vehicles (HEVs), including testing the HEV batteries when both the vehicles and batteries are new and at the conclusion of 160,000 miles of on road fleet testing. This report documents battery testing performed for the 2010 Honda Insight HEV (VIN: JHMZE2H59AS011748). Battery testing was performed by the Electric Transportation Engineering Corporation dba ECOtality North America. The Idaho National Laboratory and ECOtality North America collaborate on the Advanced Vehicle Testing Activitymore » for the Vehicle Technologies Program of the U.S. Department of Energy.« less

2010 Ford Fusion VIN 4757 Hybrid Electric Vehicle Battery Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tyler Gray; Matthew Shirk

2013-01-01

The U.S. Department of Energy Advanced Vehicle Testing Activity Program consists of vehicle, battery, and infrastructure testing on advanced technology related to transportation. The activity includes tests on hybrid electric vehicles (HEVs), including testing HEV batteries when both the vehicles and batteries are new and at the conclusion of 160,000 miles of on-road fleet testing. This report documents battery testing performed for the 2010 Ford Fusion HEV (VIN: 3FADP0L34AR144757). Battery testing was performed by the Electric Transportation Engineering Corporation dba ECOtality North America. The Idaho National Laboratory and ECOtality North America collaborate on the Advanced Vehicle Testing Activity for themore » Vehicle Technologies Program of the U.S. Department of Energy.« less

Design and development of a structural mode control system

NASA Technical Reports Server (NTRS)

1977-01-01

A program was conducted to compile and document some of the existing information about the conceptual design, development, and tests of the B-1 structural mode control system (SMCS) and its impact on ride quality. This report covers the following topics: (1) Rationale of selection of SMCS to meet ride quality criteria versus basic aircraft stiffening. (2) Key considerations in designing an SMCS, including vane geometry, rate and deflection requirements, power required, compensation network design, and fail-safe requirements. (3) Summary of key results of SMCS vane wind tunnel tests. (4) SMCS performance. (5) SMCS design details, including materials, bearings, and actuators. (6) Results of qualification testing of SMCS on the "Iron Bird" flight control simulator, and lab qualification testing of the actuators. (7) Impact of SMCS vanes on engine inlet characteristics from wind tunnel tests.

An optimized implementation of a fault-tolerant clock synchronization circuit

NASA Technical Reports Server (NTRS)

Torres-Pomales, Wilfredo

1995-01-01

A fault-tolerant clock synchronization circuit was designed and tested. A comparison to a previous design and the procedure followed to achieve the current optimization are included. The report also includes a description of the system and the results of tests performed to study the synchronization and fault-tolerant characteristics of the implementation.

The Not-so-Random Drunkard's Walk

ERIC Educational Resources Information Center

Ehrhardt, George

2013-01-01

This dataset contains the results of a quasi-experiment, testing Karl Pearson's "drunkard's walk" analogy for an abstract random walk. Inspired by the alternate hypothesis that drunkards stumble to the side of their dominant hand, it includes data on intoxicated test subjects walking a 10' line. Variables include: the…

Results of Rolling Resistance Measurements of Twelve Radial Passenger Car Tires

DOT National Transportation Integrated Search

1980-01-01

The Calspan Tire Research Facility is described, including the test procedure, a tire test schedule, and a tire identification schedule for testing low-rolling resistance radial passenger car tires. The equilibrium rolling resistance was measured on ...

Update on HER2 testing for breast and upper gastrointestinal tract cancers.

PubMed

Ross, Jeffrey S

2011-06-01

With the regulatory approvals in Europe and the USA of trastuzumab-based anti-HER2 targeted therapy for upper gastrointestinal cancers in 2010, HER2 testing has now become universal for newly diagnosed cases of both breast cancer and adenocarcinomas of esophagus, stomach and gastroesophageal origin. In the 12 years or more since the approval of trastuzumab for breast cancer, general refinements in approaches to HER2 testing, including a greater understanding of the implications of preanalytic factors impacting the test results and the application of standardization of reporting of HER2 test results, have taken place. There has also been continuing development in breast cancer with the introduction of new HER2 tests, including non-FISH tests, dimerization assays, phosphorylated HER2 receptor tests, mRNA-based tests, HER2 gene sequencing tests and the application of HER2 testing to circulating tumor cells. Most recently, the introduction of HER2 testing for upper gastrointentinal malignancies has emphasized the need for performing and interpreting slide-based assays in a manner unique to these specimens and not to apply the breast cancer testing protocols to esophageal and gastric adenocarcinomas.

Correlation between skin-prick testing, individual specific IgE tests, and a multiallergen IgE assay for allergy detection in patients with chronic rhinitis.

PubMed

Cho, Jae Hoon; Suh, Jeffrey D; Kim, Jin Kook; Hong, Seok-Chan; Park, Il-Ho; Lee, Heung-Man

2014-01-01

Allergy test results can differ based on the method used. The most common tests include skin-prick testing (SPT) and in vitro tests to detect allergen-specific IgE. This study was designed to assess allergy test results using SPT, individual specific IgE tests, and a multiallergen IgE assay (multiple allergen simultaneous test) in patients with chronic rhinitis and controls. One hundred forty total patients were prospectively enrolled in the study, including 100 patients with chronic rhinitis and 40 control patients without atopy. All eligible patients underwent SPT, serum analysis using individual specific IgE test, and multiple allergen simultaneous test against 10 common allergens. Allergy test results were then compared to identify correlation and interest agreement. There was an 81-97% agreement between SPT and individual specific IgE test in allergen detection and an 80-98% agreement between SPT and multiple allergen simultaneous test. Individual specific IgE test and multiple allergen simultaneous test allergy detection prevalence was generally similar to SPT in patients with chronic rhinitis. All control patients had negative SPT (0/40), but low positive results were found with both individual specific IgE test (5-12.5%) and multiple allergen simultaneous test (2.5-7.5%) to some allergens, especially cockroach, Dermatophagoides farina, and ragweed. Agreement and correlation between individual specific IgE test and multiple allergen simultaneous test were good to excellent for a majority of tested allergens. This study shows good agreement and correlation between SPT with individual specific IgE test and multiple allergen simultaneous test on a majority of the tested allergens for patients with chronic rhinitis. Comparing the two in vitro tests, individual specific IgE test agrees with SPT better than multiple allergen simultaneous test.

High-Alpha Research Vehicle (HARV) longitudinal controller: Design, analyses, and simulation resultss

NASA Technical Reports Server (NTRS)

Ostroff, Aaron J.; Hoffler, Keith D.; Proffitt, Melissa S.; Brown, Philip W.; Phillips, Michael R.; Rivers, Robert A.; Messina, Michael D.; Carzoo, Susan W.; Bacon, Barton J.; Foster, John F.

1994-01-01

This paper describes the design, analysis, and nonlinear simulation results (batch and piloted) for a longitudinal controller which is scheduled to be flight-tested on the High-Alpha Research Vehicle (HARV). The HARV is an F-18 airplane modified for and equipped with multi-axis thrust vectoring. The paper includes a description of the facilities, a detailed review of the feedback controller design, linear analysis results of the feedback controller, a description of the feed-forward controller design, nonlinear batch simulation results, and piloted simulation results. Batch simulation results include maximum pitch stick agility responses, angle of attack alpha captures, and alpha regulation for full lateral stick rolls at several alpha's. Piloted simulation results include task descriptions for several types of maneuvers, task guidelines, the corresponding Cooper-Harper ratings from three test pilots, and some pilot comments. The ratings show that desirable criteria are achieved for almost all of the piloted simulation tasks.

Performance of the Primary Mirror Center-of-Curvature Optical Metrology System during Cryogenic Testing of the JWST Pathfinder Telescope

NASA Technical Reports Server (NTRS)

Hadaway, James B.; Wells, Conrad; Olczak, Gene; Waldman, Mark; Whitman, Tony; Cosentino, Joseph; Connolly, Mark; Chaney, David; Telfer, Randal

2016-01-01

The JWST primary mirror consists of 18 1.5 m hexagonal segments, each with 6-DoF and RoC adjustment. The telescope will be tested at its cryogenic operating temperature at Johnson Space Center. The testing will include center-of-curvature measurements of the PM, using the Center-of-Curvature Optical Assembly (COCOA) and the Absolute Distance Meter Assembly (ADMA). The performance of these metrology systems, including hardware, software, procedures, was assessed during two cryogenic tests at JSC, using the JWST Pathfinder telescope. This paper describes the test setup, the testing performed, and the resulting metrology system performance.

An approach to operating system testing

NASA Technical Reports Server (NTRS)

Sum, R. N., Jr.; Campbell, R. H.; Kubitz, W. J.

1984-01-01

To ensure the reliability and performance of a new system, it must be verified or validated in some manner. Currently, testing is the only resonable technique available for doing this. Part of this testing process is the high level system test. System testing is considered with respect to operating systems and in particular UNIX. This consideration results in the development and presentation of a good method for performing the system test. The method includes derivations from the system specifications and ideas for management of the system testing project. Results of applying the method to the IBM System/9000 XENIX operating system test and the development of a UNIX test suite are presented.

Validating Laboratory Results in Electronic Health Records

PubMed Central

Perrotta, Peter L.; Karcher, Donald S.

2017-01-01

Context Laboratories must ensure that the test results and pathology reports they transmit to a patient’s electronic health record (EHR) are accurate, complete, and presented in a useable format. Objective To determine the accuracy, completeness, and formatting of laboratory test results and pathology reports transmitted from the laboratory to the EHR. Design Participants from 45 institutions retrospectively reviewed results from 16 different laboratory tests, including clinical and anatomic pathology results, within the EHR used by their providers to view laboratory results. Results were evaluated for accuracy, presence of required elements, and usability. Both normal and abnormal results were reviewed for tests, some of which were performed in-house and others at a reference laboratory. Results Overall accuracy for test results transmitted to the EHR was greater than 99.3% (1052 of 1059). There was lower compliance for completeness of test results, with 69.6% (732 of 1051) of the test results containing all essential reporting elements. Institutions that had fewer than half of their orders entered electronically had lower test result completeness rates. The rate of appropriate formatting of results was 90.9% (98 of 1010). Conclusions The great majority of test results are accurately transmitted from the laboratory to the EHR; however, lower percentages are transmitted completely and in a useable format. Laboratories should verify the accuracy, completeness, and format of test results at the time of test implementation, after test changes, and periodically. PMID:27575266

Special environmental control and life support equipment test analyses and hardware

NASA Technical Reports Server (NTRS)

Callahan, David M.

1995-01-01

This final report summarizes NAS8-38250 contract events, 'Special Environmental Control and Life Support Systems Test Analysis and Hardware'. This report is technical and includes programmatic development. Key to the success of this contract was the evaluation of Environmental Control and Life Support Systems (ECLSS) test results via sophisticated laboratory analysis capabilities. The history of the contract, including all subcontracts, is followed by the support and development of each Task.

Statistical analysis of Skylab 3. [endocrine/metabolic studies of astronauts

NASA Technical Reports Server (NTRS)

Johnston, D. A.

1974-01-01

The results of endocrine/metabolic studies of astronauts on Skylab 3 are reported. One-way analysis of variance, contrasts, two-way unbalanced analysis of variance, and analysis of periodic changes in flight are included. Results for blood tests, and urine tests are presented.

Fuel Efficiency Mapping of a 2014 6-Cylinder GM EcoTec 4.3L Engine with Cylinder Deactivation (SAE 2016-01-0662)

EPA Science Inventory

This paper describes the method and test results of the engine dyno portion of the benchmarking test results including engine fuel consumption maps showing the effects of cylinder deactivation engine technology.

Second generation heliostat development for solar central receiver systems. Volume 4, appendices F-J: Control software test results manufacturing pile installation pile coatings

NASA Astrophysics Data System (ADS)

1981-03-01

Support documentation for a second generation heliostat project is presented. Flowcharts of control software are included. Numerical and graphic test results are provided. Project management information is also provided.

Effect of Changing the Center of Gravity on Human Performance in Simulated Lunar Gravity

NASA Technical Reports Server (NTRS)

Chappell, Steven P.; Norcross, Jason R.; Gernhardt, Michael L.

2010-01-01

The presentation slides include: Moving Past Apollo, Testing in Analog Environments, NEEMO/NBL CG (center of gravity) Studies, Center of Gravity Test Design and Methods, CG Suited Locations and Results, CG Individual Considerations, CG Shirt-Sleeve Locations and Results.

Driving competences and neuropsychological factors associated to driving counseling in multiple sclerosis.

PubMed

Badenes, Dolors; Garolera, Maite; Casas, Laura; Cejudo-Bolivar, Juan Carlos; de Francisco, Jorge; Zaragoza, Silvia; Calzado, Noemi; Aguilar, Miquel

2014-05-01

Multiple Sclerosis (MS) significantly impacts daily living activities, including car driving. To investigate driving difficulties experienced with MS, we compared 50 MS patients with minor or moderate disability and 50 healthy controls (HC) using computerized driving tests (the ASDE driver test and the Useful Field of View (UFOV) test) and neuropsychological tests. Inclusion criteria included being active drivers. We evaluated whether cognitive deterioration in MS is associated with the results of driving tests by comparing MS patients without cognitive deterioration with HC. The results indicated that the MS patients performed worse than the HCs in attention, information processing, working memory and visuomotor coordination tasks. Furthermore, MS patients with cognitive impairments experienced more difficulties in the driving tests than did the non-impaired MS patients. Motor dysfunction associated with MS also played an important role in this activity. The results of this study suggest that MS should be assessed carefully and that special emphasis should be placed on visuomotor coordination and executive functions because patients with minor motor disability and subtle cognitive impairments can pass measures predictive of driving safety.

How well do general practitioners manage laboratory test results for patients with diabetes mellitus and cardiovascular disease?: A systematic review.

PubMed

McCaughey, Euan J; Li, Julie; Badrick, Tony C; Westbrook, Johanna I; Georgiou, Andrew

2017-10-01

To evaluate how well general practitioners (GPs) manage and respond to laboratory results for patients with diabetes mellitus (DM) and cardiovascular disease (CVD). MEDLINE, CINAHL, Embase, EBM reviews, ProQuest and Scopus. Peer-reviewed journal articles published between 2000 and 2015 that assessed GPs' management of laboratory results for patients with DM or CVD. Study design and demographics, laboratory tests and key findings relating to GP management of laboratory results were extracted from studies. Thirteen articles were included, comprising seven studies which utilized surveys, four observational studies, one cohort study and one randomized controlled trial. Findings indicate that GPs often overestimate the risk of complications associated with DM and CVD based on laboratory results and have unrealistically high expectations regarding the precision of laboratory tests. Considerable variation existed in the use of repeat testing for diagnostic confirmation and in GPs' identification of the difference between two consecutive results required to indicate a change in patient condition. GPs also often failed to initiate appropriate treatment for patients with DM and CVD based on laboratory results. Feedback to GPs about their test ordering patterns and educational messages on laboratory results improved clinical outcomes. Evidence about how well GPs manage results and its impact on patient outcomes remains weak and inconclusive. This review identified a number of areas where interventions could support GPs to improve the interpretation and management of laboratory test results, including feedback to GPs and educational messages on test result reports. © The Author 2017. Published by Oxford University Press in association with the International Society for Quality in Health Care. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

SRG110 Stirling Generator Dynamic Simulator Vibration Test Results and Analysis Correlation

NASA Technical Reports Server (NTRS)

Suarez, Vicente J.; Lewandowski, Edward J.; Callahan, John

2006-01-01

The U.S. Department of Energy (DOE), Lockheed Martin (LM), and NASA Glenn Research Center (GRC) have been developing the Stirling Radioisotope Generator (SRG110) for use as a power system for space science missions. The launch environment enveloping potential missions results in a random input spectrum that is significantly higher than historical RPS launch levels and is a challenge for designers. Analysis presented in prior work predicted that tailoring the compliance at the generator-spacecraft interface reduced the dynamic response of the system thereby allowing higher launch load input levels and expanding the range of potential generator missions. To confirm analytical predictions, a dynamic simulator representing the generator structure, Stirling convertors and heat sources was designed and built for testing with and without a compliant interface. Finite element analysis was performed to guide the generator simulator and compliant interface design so that test modes and frequencies were representative of the SRG110 generator. This paper presents the dynamic simulator design, the test setup and methodology, test article modes and frequencies and dynamic responses, and post-test analysis results. With the compliant interface, component responses to an input environment exceeding the SRG110 qualification level spectrum were all within design allowables. Post-test analysis included finite element model tuning to match test frequencies and random response analysis using the test input spectrum. Analytical results were in good overall agreement with the test results and confirmed previous predictions that the SRG110 power system may be considered for a broad range of potential missions, including those with demanding launch environments.

SRG110 Stirling Generator Dynamic Simulator Vibration Test Results and Analysis Correlation

NASA Technical Reports Server (NTRS)

Lewandowski, Edward J.; Suarez, Vicente J.; Goodnight, Thomas W.; Callahan, John

2007-01-01

The U.S. Department of Energy (DOE), Lockheed Martin (LM), and NASA Glenn Research Center (GRC) have been developing the Stirling Radioisotope Generator (SRG110) for use as a power system for space science missions. The launch environment enveloping potential missions results in a random input spectrum that is significantly higher than historical radioisotope power system (RPS) launch levels and is a challenge for designers. Analysis presented in prior work predicted that tailoring the compliance at the generator-spacecraft interface reduced the dynamic response of the system thereby allowing higher launch load input levels and expanding the range of potential generator missions. To confirm analytical predictions, a dynamic simulator representing the generator structure, Stirling convertors and heat sources were designed and built for testing with and without a compliant interface. Finite element analysis was performed to guide the generator simulator and compliant interface design so that test modes and frequencies were representative of the SRG110 generator. This paper presents the dynamic simulator design, the test setup and methodology, test article modes and frequencies and dynamic responses, and post-test analysis results. With the compliant interface, component responses to an input environment exceeding the SRG110 qualification level spectrum were all within design allowables. Post-test analysis included finite element model tuning to match test frequencies and random response analysis using the test input spectrum. Analytical results were in good overall agreement with the test results and confirmed previous predictions that the SRG110 power system may be considered for a broad range of potential missions, including those with demanding launch environments.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Geoffrey Wayne; Leonard, Philip; Hartline, Ernest Leon

High Explosives Science and Technology (M-7) completed all required formulation and testing of Remediated Nitrate Salt (RNS) surrogates on April 27, 2016 as specified in PLAN-TA9-2443 Rev B, "Remediated Nitrate Salt (RNS) Surrogate Formulation and Testing Standard Procedure", released February 16, 2016. This report summarizes the results of the work and also includes additional documentation required in that test plan. All formulation and testing was carried out according to PLAN-TA9-2443 Rev B. The work was carried out in three rounds, with the full matrix of samples formulated and tested in each round. Results from the first round of formulation andmore » testing were documented in memorandum M7-J6-6042, " Results from First Round of Remediated Nitrate Salt Surrogate Formulation and Testing." Results from the second round of formulation and testing were documented in M7-16-6053 , "Results from the Second Round of Remediated Nitrate Salt Surrogate Formulation and Testing." Initial results from the third round were documented in M7-16-6057, "Initial Results from the Third Round of Remediated Nitrate Salt Formulation and Testing."« less

External quality assurance of HER2 fluorescence in situ hybridisation testing: results of a UK NEQAS pilot scheme.

PubMed

Bartlett, John M S; Ibrahim, Merdol; Jasani, Bharat; Morgan, John M; Ellis, Ian; Kay, Elaine; Magee, Hilary; Barnett, Sarah; Miller, Keith

2007-07-01

Trastuzumab provides clinical benefit for advanced and early breast cancer patients whose tumours over-express or have gene amplification of the HER2 oncogene. The UK National External Quality Assessment Scheme (NEQAS) for immunohistochemical testing was established to assess and improve the quality of HER2 immunohistochemical testing. However, until recently, no provision was available for HER2 fluorescence in situ hybridisation (FISH) testing. A pilot scheme was set up to review the performance of FISH testing in clinical diagnostic laboratories. FISH was performed in 6 reference and 31 participating laboratories using a cell line panel with known HER2 status. Using results from reference laboratories as a criterion for acceptable performance, 60% of all results returned by participants were appropriate and 78% either appropriate or acceptable. However, 22.4% of results returned were deemed inappropriate, including 13 cases (4.2%) where a misdiagnosis would have been made had these been clinical specimens. The results of three consecutive runs show that both reference laboratories and a proportion of routine clinical diagnostic (about 25%) centres can consistently achieve acceptable quality control of HER2 testing. Data from a significant proportion of participating laboratories show that further steps are required, including those taken via review of performance under schemes such as NEQAS, to improve quality of HER2 testing by FISH in the "real world".

Significance of hydrogen breath tests in children with suspected carbohydrate malabsorption

PubMed Central

2014-01-01

Background Hydrogen breath tests are noninvasive procedures frequently applied in the diagnostic workup of functional gastrointestinal disorders. Here, we review hydrogen breath test results and the occurrence of lactose, fructose and sorbitol malabsorption in pediatric patients; and determine the significance of the findings and the outcome of patients with carbohydrate malabsorption. Methods We included 206 children (88 male, 118 female, median age 10.7 years, range 3–18 years) with a total of 449 hydrogen breath tests (lactose, n = 161; fructose, n = 142; sorbitol, n = 146) into a retrospective analysis. Apart from test results, we documented symptoms, the therapeutic consequences of the test, the outcome and the overall satisfaction of the patients and families. Results In total, 204 (46%) of all breath tests were positive. Long-term follow-up data could be collected from 118 patients. Of 79 patients (67%) who were put on a diet reduced in lactose, fructose and/or sorbitol, the majority (92%, n = 73) reported the diet to be strict and only 13% (n = 10) had no response to diet. Most families (96%, n = 113) were satisfied by the test and the therapy. There were only 21 tests (5%) with a borderline result because the criteria for a positive result were only partially met. Conclusions Hydrogen breath tests can be helpful in the evaluation of children with gastrointestinal symptoms including functional intestinal disorders. If applied for a variety of carbohydrates but only where indicated, around two-third of all children have positive results. The therapeutic consequences are successfully relieving symptoms in the vast majority of patients. PMID:24575947

Point-of-Care Viral Load Testing for Sub-Saharan Africa: Informing a Target Product Profile.

PubMed

Phillips, Andrew N; Cambiano, Valentina; Nakagawa, Fumiyo; Ford, Deborah; Apollo, Tsitsi; Murungu, Joseph; Rousseau, Christine; Garnett, Geoff; Ehrenkranz, Peter; Bansi-Matharu, Loveleen; Vojnov, Lara; Katz, Zachary; Peeling, Rosanna; Revill, Paul

2016-09-01

Point-of-care viral load tests are being developed to monitor patients on antiretroviral therapy (ART) in sub-Saharan Africa. Test design involves trade-offs between test attributes, including accuracy, complexity, robustness, and cost. We used a model of the human immunodeficiency virus epidemic and ART program in Zimbabwe and found that the attributes of a viral load testing approach that are most influential for cost effectiveness are avoidance of a high proportion of failed tests or results not received, use of an approach that best facilitates retention on ART, and the ability to facilitate greater use of differentiated care, including through expanding coverage of testing availability.

Point-of-Care Viral Load Testing for Sub-Saharan Africa: Informing a Target Product Profile

PubMed Central

Phillips, Andrew N.; Cambiano, Valentina; Nakagawa, Fumiyo; Ford, Deborah; Apollo, Tsitsi; Murungu, Joseph; Rousseau, Christine; Garnett, Geoff; Ehrenkranz, Peter; Bansi-Matharu, Loveleen; Vojnov, Lara; Katz, Zachary; Peeling, Rosanna; Revill, Paul

2016-01-01

Point-of-care viral load tests are being developed to monitor patients on antiretroviral therapy (ART) in sub-Saharan Africa. Test design involves trade-offs between test attributes, including accuracy, complexity, robustness, and cost. We used a model of the human immunodeficiency virus epidemic and ART program in Zimbabwe and found that the attributes of a viral load testing approach that are most influential for cost effectiveness are avoidance of a high proportion of failed tests or results not received, use of an approach that best facilitates retention on ART, and the ability to facilitate greater use of differentiated care, including through expanding coverage of testing availability. PMID:27704016

Multiplex tests to identify gastrointestinal bacteria, viruses and parasites in people with suspected infectious gastroenteritis: a systematic review and economic analysis.

PubMed

Freeman, Karoline; Mistry, Hema; Tsertsvadze, Alexander; Royle, Pam; McCarthy, Noel; Taylor-Phillips, Sian; Manuel, Rohini; Mason, James

2017-04-01

Gastroenteritis is a common, transient disorder usually caused by infection and characterised by the acute onset of diarrhoea. Multiplex gastrointestinal pathogen panel (GPP) tests simultaneously identify common bacterial, viral and parasitic pathogens using molecular testing. By providing test results more rapidly than conventional testing methods, GPP tests might positively influence the treatment and management of patients presenting in hospital or in the community. To systematically review the evidence for GPP tests [xTAG ® (Luminex, Toronto, ON, Canada), FilmArray (BioFire Diagnostics, Salt Lake City, UT, USA) and Faecal Pathogens B (AusDiagnostics, Beaconsfield, NSW, Australia)] and to develop a de novo economic model to compare the cost-effectiveness of GPP tests with conventional testing in England and Wales. Multiple electronic databases including MEDLINE, EMBASE, Web of Science and the Cochrane Database were searched from inception to January 2016 (with supplementary searches of other online resources). Eligible studies included patients with acute diarrhoea; comparing GPP tests with standard microbiology techniques; and patient, management, test accuracy or cost-effectiveness outcomes. Quality assessment of eligible studies used tailored Quality Assessment of Diagnostic Accuracy Studies-2, Consolidated Health Economic Evaluation Reporting Standards and Philips checklists. The meta-analysis included positive and negative agreement estimated for each pathogen. A de novo decision tree model compared patients managed with GPP testing or comparable coverage with patients managed using conventional tests, within the Public Health England pathway. Economic models included hospital and community management of patients with suspected gastroenteritis. The model estimated costs (in 2014/15 prices) and quality-adjusted life-year losses from a NHS and Personal Social Services perspective. Twenty-three studies informed the review of clinical evidence (17 xTAG, four FilmArray, two xTAG and FilmArray, 0 Faecal Pathogens B). No study provided an adequate reference standard with which to compare the test accuracy of GPP with conventional tests. A meta-analysis (of 10 studies) found considerable heterogeneity; however, GPP testing produces a greater number of pathogen-positive findings than conventional testing. It is unclear whether or not these additional 'positives' are clinically important. The review identified no robust evidence to inform consequent clinical management of patients. There is considerable uncertainty about the cost-effectiveness of GPP panels used to test for suspected infectious gastroenteritis in hospital and community settings. Uncertainties in the model include length of stay, assumptions about false-positive findings and the costs of tests. Although there is potential for cost-effectiveness in both settings, key modelling assumptions need to be verified and model findings remain tentative. No test-treat trials were retrieved. The economic model reflects one pattern of care, which will vary across the NHS. The systematic review and cost-effectiveness model identify uncertainties about the adoption of GPP tests within the NHS. GPP testing will generally correctly identify pathogens identified by conventional testing; however, these tests also generate considerable additional positive results of uncertain clinical importance. An independent reference standard may not exist to evaluate alternative approaches to testing. A test-treat trial might ascertain whether or not additional GPP 'positives' are clinically important or result in overdiagnoses, whether or not earlier diagnosis leads to earlier discharge in patients and what the health consequences of earlier intervention are. Future work might also consider the public health impact of different testing treatments, as test results form the basis for public health surveillance. This study is registered as PROSPERO CRD2016033320. The National Institute for Health Research Health Technology Assessment programme.

40 CFR 86.1828-01 - Emission data vehicle selection.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., considering all exhaust emission constituents, all exhaust test procedures, and the potential impact of air conditioning on test results. The selected vehicle will include an air conditioning engine code unless the.... (a) FTP and SFTP testing. Within each test group, the vehicle configuration shall be selected which...

40 CFR 86.1828-01 - Emission data vehicle selection.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., considering all exhaust emission constituents, all exhaust test procedures, and the potential impact of air conditioning on test results. The selected vehicle will include an air conditioning engine code unless the.... (a) FTP and SFTP testing. Within each test group, the vehicle configuration shall be selected which...

40 CFR 86.1828-01 - Emission data vehicle selection.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., considering all exhaust emission constituents, all exhaust test procedures, and the potential impact of air conditioning on test results. The selected vehicle will include an air conditioning engine code unless the.... (a) FTP and SFTP testing. Within each test group, the vehicle configuration shall be selected which...

40 CFR 86.1828-01 - Emission data vehicle selection.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., considering all exhaust emission constituents, all exhaust test procedures, and the potential impact of air conditioning on test results. The selected vehicle will include an air conditioning engine code unless the.... (a) FTP and SFTP testing. Within each test group, the vehicle configuration shall be selected which...

Acceptability of self-conducted home-based HIV testing among men who have sex with men in Brazil: data from an on-line survey

PubMed Central

Lippman, Sheri A.; Périssé, André R. S.; Veloso, Valdiléa G.; Sullivan, Patrick S.; Buchbinder, Susan; Sineath, R. Craig; Grinsztejn, Beatriz

2014-01-01

The Brazilian HIV/AIDS epidemic is concentrated among men who have sex with men (MSM), however HIV testing rates among MSM are not commensurate with their risk. Strategies to expand early diagnosis may include use of self-conducted home-based testing kits, which are now available for purchase in the US. In April 2011 we conducted a survey with Brazilian MSM using Facebook to assess HIV testing preferences and acceptability of home-based testing. Among 356 previously tested, HIV-negative MSM, 47% reported a preference for home-based testing, 27% preferred clinic-based testing, and 26% had no preference. Less frequent testers and those who had considered testing but failed to test were more likely to prefer home-based testing. Close to 90% reported that they would use self-test kits; 62% and 54% said they would use home-based testing to make choices about unprotected sex with regular and new partners, respectively. Concerns included difficulty to understand the tests (32%) and receiving results alone (23%). Overall, home-based testing may appeal to MSM and result in increased testing frequency. Research on feasibility and utilization of self-tests in practice is needed. PMID:24896048

Field Testing of Cryogenic Carbon Capture

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sayre, Aaron; Frankman, Dave; Baxter, Andrew

Sustainable Energy Solutions has been developing Cryogenic Carbon Capture™ (CCC) since 2008. In that time two processes have been developed, the External Cooling Loop and Compressed Flue Gas Cryogenic Carbon Capture processes (CCC ECL™ and CCC CFG™ respectively). The CCC ECL™ process has been scaled up to a 1TPD CO2 system. In this process the flue gas is cooled by an external refrigerant loop. SES has tested CCC ECL™ on real flue gas slip streams from subbituminous coal, bituminous coal, biomass, natural gas, shredded tires, and municipal waste fuels at field sites that include utility power stations, heating plants, cementmore » kilns, and pilot-scale research reactors. The CO2 concentrations from these tests ranged from 5 to 22% on a dry basis. CO2 capture ranged from 95-99+% during these tests. Several other condensable species were also captured including NO2, SO2 and PMxx at 95+%. NO was also captured at a modest rate. The CCC CFG™ process has been scaled up to a .25 ton per day system. This system has been tested on real flue gas streams including subbituminous coal, bituminous coal and natural gas at field sites that include utility power stations, heating plants, and pilot-scale research reactors. CO2 concentrations for these tests ranged from 5 to 15% on a dry basis. CO2 capture ranged from 95-99+% during these tests. Several other condensable species were also captured including NO2, SO2 and PMxx at 95+%. NO was also captured at 90+%. Hg capture was also verified and the resulting effluent from CCC CFG™ was below a 1ppt concentration. This paper will focus on discussion of the capabilities of CCC, the results of field testing and the future steps surrounding the development of this technology.« less

Transonic flight flutter tests of a control surface utilizing an impedance response technique

NASA Technical Reports Server (NTRS)

Mirowitz, L. I.

1975-01-01

Transonic flight flutter tests of the XF3H-1 Demon Airplane were conducted utilizing a frequency response technique in which the oscillating rudder provides the means of system excitation. These tests were conducted as a result of a rudder flutter incident in the transonic speed range. The technique employed is presented including a brief theoretical development of basic concepts. Test data obtained during the flight are included and the method of interpretation of these data is indicated. This method is based on an impedance matching technique. It is shown that an artificial stabilizing device, such as a damper, may be incorporated in the system for test purposes without complicating the interpretation of the test results of the normal configuration. Data are presented which define the margin of stability introduced to the originally unstable rudder by design changes which involve higher control system stiffness and external damper. It is concluded that this technique of flight flutter testing is a feasible means of obtaining flutter stability information in flight.

High HIV Prevalence, Suboptimal HIV Testing, and Low Knowledge of HIV-Positive Serostatus Among Injection Drug Users in St. Petersburg, Russia

PubMed Central

Toussova, Olga V.; Verevochkin, Sergei V.; Barbour, Russell; Heimer, Robert; Kozlov, Andrei P.

2011-01-01

The purpose of this analysis was to estimate human immunodeficiency virus (HIV) prevalence and testing patterns among injection drug users (IDUs) in St. Petersburg, Russia. HIV prevalence among 387 IDUs in the sample was 50%. Correlates of HIV-positive serostatus included unemployment, recent unsafe injections, and history/current sexually transmitted infection. Seventy-six percent had been HIV tested, but only 22% of those who did not report HIV-positive serostatus had been tested in the past 12 months and received their test result. Correlates of this measure included recent doctor visit and having been in prison or jail among men. Among the 193 HIV-infected participants, 36% were aware of their HIV-positive serostatus. HIV prevalence is high and continuing to increase in this population. Adequate coverage of HIV testing has not been achieved, resulting in poor knowledge of positive serostatus. Efforts are needed to better understand motivating and deterring factors for HIV testing in this setting. PMID:18843531

[A pseudo-outbreak of pharyngeal gonorrhoea related to a false-positive PCR-result].

PubMed

Verzijl, A; Berretty, P J M; Erceg, A; Krekels, G A M; Van den Brule, A J C; Boel, C H E

2007-03-24

Nucleic acid amplification tests, including the polymerase chain reaction (PCR), are sensitive and specific tests that are often used for diagnosing sexually transmitted diseases (STDs). A pseudo-outbreak of pharyngeal gonorrhoea in a group of prostitutes turned out to have been caused by false-positive test results due to commensal oropharyngeal Neisseria species. Specific molecular tests may yield erroneous results. When the results of an STD study have major consequences at a legal or social level, it is advisable, in consultation with a medical microbiologist, to take a sample for culture or to carry out a second molecular test aimed at a different part of the bacterial genome.

Routine testing for blood-borne viruses in prisons: a systematic review

PubMed Central

Pevalin, David J.; O’Moore, Éamonn

2015-01-01

Background: People in prison have a higher burden of blood-borne virus (BBV) infection than the general population, and prisons present an opportunity to test for BBVs in high-risk, underserved groups. Changes to the BBV testing policies in English prisons have recently been piloted. This review will enable existing evidence to inform policy revisions. We describe components of routine HIV, hepatitis B and C virus testing policies in prisons and quantify testing acceptance, coverage, result notification and diagnosis. Methods: We searched five databases for studies of both opt-in (testing offered to all and the individual chooses to have the test or not) and opt-out (the individual is informed the test will be performed unless they actively refuse) prison BBV testing policies. Results: Forty-four studies published between 1989 and 2013 met the inclusion criteria. Of these, 82% were conducted in the USA, 91% included HIV testing and most tested at the time of incarceration. HIV testing acceptance rates ranged from 22 to 98% and testing coverage from 3 to 90%. Mixed results were found for equity in uptake. Six studies reported reasons for declining a test including recent testing and fear. Conclusions: While the quality of evidence is mixed, this review suggests that reasonable rates of uptake can be achieved with opt-in and, even better, with opt-out HIV testing policies. Little evidence was found relating to hepatitis testing. Policies need to specify exclusion criteria and consider consent processes, type of test and timing of the testing offer to balance acceptability, competence and availability of individuals. PMID:26219884

Comparative efficacy of several disinfectants in suspension and carrier tests against Haemophilus parasuis serovars 1 and 5.

PubMed

Rodríguez Ferri, E F; Martínez, S; Frandoloso, R; Yubero, S; Gutiérrez Martín, C B

2010-06-01

The comparative efficacy of 16 active compounds (including the most commonly used chemical groups) and 10 commercial formulations against Haemophilus parasuis serovars 1 and 5 was studied. These organisms were tested in suspension and carrier tests in the presence and absence of serum as representative of organic matter. Chloramine-T and half of the formulations from commercial sources (most of them including quaternary ammonium compounds) were effective in both in vitro tests, regardless of the presence or absence of organic load. All 26 disinfectants except for an iodophor (0.1% available iodine) resulted in at least 3-log(10) reduction in colony-forming units in suspension test, and most of them resulted in the maximal level of detection (>6-log(10) reduction). On the other hand, disinfectants were not as effective in carrier test as in suspension test, and the presence of serum considerably reduced the activities of most of the compounds tested, especially in carrier test. These results suggest the importance of selecting suitable disinfection for routine use on surfaces contaminated with H. parasuis, particularly when organic matter is present. Chloramine-T and formulations 2 and 7-10 are recommended for a complete inactivation of H. parasuis in swine herds. Copyright 2009 Elsevier Ltd. All rights reserved.

Statistical correlation of structural mode shapes from test measurements and NASTRAN analytical values

NASA Technical Reports Server (NTRS)

Purves, L.; Strang, R. F.; Dube, M. P.; Alea, P.; Ferragut, N.; Hershfeld, D.

1983-01-01

The software and procedures of a system of programs used to generate a report of the statistical correlation between NASTRAN modal analysis results and physical tests results from modal surveys are described. Topics discussed include: a mathematical description of statistical correlation, a user's guide for generating a statistical correlation report, a programmer's guide describing the organization and functions of individual programs leading to a statistical correlation report, and a set of examples including complete listings of programs, and input and output data.

Statistics 101 for Radiologists.

PubMed

Anvari, Arash; Halpern, Elkan F; Samir, Anthony E

2015-10-01

Diagnostic tests have wide clinical applications, including screening, diagnosis, measuring treatment effect, and determining prognosis. Interpreting diagnostic test results requires an understanding of key statistical concepts used to evaluate test efficacy. This review explains descriptive statistics and discusses probability, including mutually exclusive and independent events and conditional probability. In the inferential statistics section, a statistical perspective on study design is provided, together with an explanation of how to select appropriate statistical tests. Key concepts in recruiting study samples are discussed, including representativeness and random sampling. Variable types are defined, including predictor, outcome, and covariate variables, and the relationship of these variables to one another. In the hypothesis testing section, we explain how to determine if observed differences between groups are likely to be due to chance. We explain type I and II errors, statistical significance, and study power, followed by an explanation of effect sizes and how confidence intervals can be used to generalize observed effect sizes to the larger population. Statistical tests are explained in four categories: t tests and analysis of variance, proportion analysis tests, nonparametric tests, and regression techniques. We discuss sensitivity, specificity, accuracy, receiver operating characteristic analysis, and likelihood ratios. Measures of reliability and agreement, including κ statistics, intraclass correlation coefficients, and Bland-Altman graphs and analysis, are introduced. © RSNA, 2015.

Test and evaluation of 23 electric vehicles for state-of-the-art assessment

NASA Technical Reports Server (NTRS)

Dustin, M. O.; Denington, R. J.

1978-01-01

Eleven of the electric vehicles were passenger cars and 12 were commercial vans. Tests were conducted in accordance with an ERDS test procedure which is based on the SAE J227a Test Procedure. Tests included range, acceleration, coast-down, and braking. The results of the tests are presented, and comments on reliability are made.

Special Educator's Complete Guide to 109 Diagnostic Tests: How To Select & Interpret Tests, Use Results in IEPs, and Remediate Specific Difficulties.

ERIC Educational Resources Information Center

Pierangelo, Roger; Giuliani, George

This manual is a guide to the special education diagnostic process and covers the various stages of evaluation, interpretation, diagnosis, prescription, and remediation. Test information includes: explanations of the most commonly used diagnostic tests, coverage of the areas measured by each test, interpretation of test patterns for commonly used…

Modified Drop Tower Impact Tests for American Football Helmets.

PubMed

Rush, G Alston; Prabhu, R; Rush, Gus A; Williams, Lakiesha N; Horstemeyer, M F

2017-02-19

A modified National Operating Committee on Standards for Athletic Equipment (NOCSAE) test method for American football helmet drop impact test standards is presented that would provide better assessment of a helmet's on-field impact performance by including a faceguard on the helmet. In this study, a merger of faceguard and helmet test standards is proposed. The need for a more robust systematic approach to football helmet testing procedures is emphasized by comparing representative results of the Head Injury Criterion (HIC), Severity Index (SI), and peak acceleration values for different helmets at different helmet locations under modified NOCSAE standard drop tower tests. Essentially, these comparative drop test results revealed that the faceguard adds a stiffening kinematic constraint to the shell that lessens total energy absorption. The current NOCSAE standard test methods can be improved to represent on-field helmet hits by attaching the faceguards to helmets and by including two new helmet impact locations (Front Top and Front Top Boss). The reported football helmet test method gives a more accurate representation of a helmet's performance and its ability to mitigate on-field impacts while promoting safer football helmets.

CO2 Washout Testing of NASA Space Suits

NASA Technical Reports Server (NTRS)

Norcross, Jason

2012-01-01

During the presentation "CO2 Washout Testing of NASA Spacesuits," Jason Norcross discussed the results of recent carbon dioxide CO2 washout testing of NASA spacesuits including the Rear Entry I-suit (REI), Enhanced Mobility Advanced Crew Escape Suit (EM-ACES), and possibly the ACES and Z-1 EVA prototype. When a spacesuit is used during ground testing, adequate CO2 washout must be provided for the suited subject. Symptoms of acute CO2 exposure depend on the partial pressure of CO2 (ppCO2) available to enter the lungs during respiration. The primary factors during ground-based testing that influence the ppCO2 level in the oronasal area include the metabolic rate of the subject and air flow through the suit. These tests were done to characterize inspired oronasal ppCO2 for a range of workloads and flow rates for which ground testing is nominally performed. During this presentation, Norcross provided descriptions of the spacesuits, test hardware, methodology, and results, as well as implications for future ground testing and verification of flight requirements.

Actuated forebody strake controls for the F-18 high alpha research vehicle

NASA Technical Reports Server (NTRS)

Murri, Daniel G.; Shah, Gautam H.; Dicarlo, Daniel J.; Trilling, Todd W.

1993-01-01

A series of ground-based studies have been conducted to develop actuated forebody strake controls for flight test evaluations using the NASA F-18 High-Alpha Research Vehicle. The actuated forebody strake concept has been designed to provide increased levels of yaw control at high angles of attack where conventional rudders become ineffective. Results are presented from tests conducted with the flight-test strake design, including static and dynamic wind-tunnel tests, transonic wind-tunnel tests, full-scale wind-tunnel tests, pressure surveys, and flow visualization tests. Results from these studies show that a pair of conformal actuated forebody strakes applied to the F-18 HARV can provide a powerful and precise yaw control device at high angles of attack. The preparations for flight testing are described, including the fabrication of flight hardware and the development of aircraft flight control laws. The primary objectives of the flight tests are to provide flight validation of the groundbased studies and to evaluate the use of this type of control to enhance fighter aircraft maneuverability.

Utilization of Ancillary Studies in the Cytologic Diagnosis of Respiratory Lesions

PubMed Central

Layfield, Lester J.; Roy-Chowdhuri, Sinchita; Baloch, Zubair; Ehya, Hormoz; Geisinger, Kim; Hsiao, Susan J.; Lin, Oscar; Lindeman, Neal I.; Roh, Michael; Schmitt, Fernando; Sidiropoulos, Nikoletta; VanderLaan, Paul A.

2017-01-01

The Papanicolaou Society of Cytopathology has developed a set of guidelines for respiratory cytology including indications for sputum examination, bronchial washings and brushings, CT-guided FNA and endobronchial ultrasound guided fine needle aspiration (EBUS-FNA), as well as recommendations for classification and criteria, ancillary testing and post-cytologic diagnosis management and follow-up. All recommendation documents are based on the expertise of committee members, an extensive literature review, and feedback from presentations at national and international conferences. The guideline documents selectively present the results of these discussions. The present document summarizes recommendations for ancillary testing of cytologic samples. Ancillary testing including microbiologic, immunocytochemical, flow cytometric, and molecular testing, including next-generation sequencing are discussed. PMID:27561242

DAME: planetary-prototype drilling automation.

PubMed

Glass, B; Cannon, H; Branson, M; Hanagud, S; Paulsen, G

2008-06-01

We describe results from the Drilling Automation for Mars Exploration (DAME) project, including those of the summer 2006 tests from an Arctic analog site. The drill hardware is a hardened, evolved version of the Advanced Deep Drill by Honeybee Robotics. DAME has developed diagnostic and executive software for hands-off surface operations of the evolved version of this drill. The DAME drill automation tested from 2004 through 2006 included adaptively controlled drilling operations and the downhole diagnosis of drilling faults. It also included dynamic recovery capabilities when unexpected failures or drilling conditions were discovered. DAME has developed and tested drill automation software and hardware under stressful operating conditions during its Arctic field testing campaigns at a Mars analog site.

DAME: Planetary-Prototype Drilling Automation

NASA Astrophysics Data System (ADS)

Glass, B.; Cannon, H.; Branson, M.; Hanagud, S.; Paulsen, G.

2008-06-01

We describe results from the Drilling Automation for Mars Exploration (DAME) project, including those of the summer 2006 tests from an Arctic analog site. The drill hardware is a hardened, evolved version of the Advanced Deep Drill by Honeybee Robotics. DAME has developed diagnostic and executive software for hands-off surface operations of the evolved version of this drill. The DAME drill automation tested from 2004 through 2006 included adaptively controlled drilling operations and the downhole diagnosis of drilling faults. It also included dynamic recovery capabilities when unexpected failures or drilling conditions were discovered. DAME has developed and tested drill automation software and hardware under stressful operating conditions during its Arctic field testing campaigns at a Mars analog site.

A three-axis flight simulator. [for testing and evaluating inertial measuring units, and flight platforms

NASA Technical Reports Server (NTRS)

Mason, M. G.

1975-01-01

A simulator is described, which was designed for testing and evaluating inertial measuring units, and flight platforms. Mechanical and electrical specifications for the outer, middle, and inner axis are presented. Test results are included.

Metal Matrix Composites: Fatigue and Fracture Testing. (Latest citations from the Aerospace Database)

NASA Technical Reports Server (NTRS)

1996-01-01

The bibliography contains citations concerning techniques and results of testing metal matrix composites for fatigue and fracture. Methods include non-destructive testing techniques, and static and cyclic techniques for assessing compression, tensile, bending, and impact characteristics.

CSF glucose test

MedlinePlus

Glucose test - CSF; Cerebrospinal fluid glucose test ... The glucose level in the CSF should be 50 to 80 mg/100 mL (or greater than 2/3 ... Abnormal results include higher and lower glucose levels. Abnormal ... or fungus) Inflammation of the central nervous system Tumor

Role of Urine Drug Testing in the Current Opioid Epidemic.

PubMed

Mahajan, Gagan

2017-12-01

While the evidence for urine drug testing for patients on chronic opioid therapy is weak, the guidelines created by numerous medical societies and state and federal regulatory agencies recommend that it be included as one of the tools used to monitor patients for compliance with chronic opioid therapy. To get the most comprehensive results, clinicians should order both an immunoassay screen and confirmatory urine drug test. The immunoassay screen, which can be performed as an in-office point-of-care test or as a laboratory-based test, is a cheap and convenient study to order. Limitations of an immunoassay screen, however, include having a high threshold of detectability and only providing qualitative information about a select number of drug classes. Because of these restrictions, clinicians should understand that immunoassay screens have high false-positive and false-negative rates. Despite these limitations, though, the results can assist the clinician with making preliminary treatment decisions. In comparison, a confirmatory urine drug test, which can only be performed as a laboratory-based test, has a lower threshold of detectability and provides both qualitative and quantitative information. A urine drug test's greater degree of specificity allows for a relatively low false-negative and false-positive rate in contrast to an immunoassay screen. Like any other diagnostic test, an immunoassay screen and a confirmatory urine drug test both possess limitations. Clinicians must keep this in mind when interpreting an unexpected test result and consult with their laboratory when in doubt about the meaning of the test result to avoid making erroneous decisions that negatively impact both the patient and clinician.

Reducing Overutilization of Testing for Clostridium difficile Infection in a Pediatric Hospital System: A Quality Improvement Initiative.

PubMed

Klatte, J Michael; Selvarangan, Rangaraj; Jackson, Mary Anne; Myers, Angela L

2016-01-01

Study objectives included addressing overuse of Clostridium difficile laboratory testing by decreasing submission rates of nondiarrheal stool specimens and specimens from children ≤12 months of age and determining resultant patient and laboratory cost savings associated with decreased testing. A multifaceted initiative was developed, and components included multiple provider education methods, computerized order entry modifications, and automatic declination from laboratory on testing stool specimens of nondiarrheal consistency and from children ≤12 months old. A run chart, demonstrating numbers of nondiarrheal plus infant stool specimens submitted over time, was developed to analyze the initiative's impact on clinicians' test-ordering practices. A p-chart was generated to evaluate the percentage of these submitted specimens tested biweekly over a 12-month period. Cost savings for patients and the laboratory were assessed at the study period's conclusion. Run chart analysis revealed an initial shift after the interventions, suggesting a temporary decrease in testing submission; however, no sustained differences in numbers of specimens submitted biweekly were observed over time. On the p-chart, the mean percentage of specimens tested before the intervention was 100%. After the intervention, the average percentage of specimens tested dropped to 53.8%. Resultant laboratory cost savings totaled nearly $3600, and patient savings on testing charges were ∼$32 000. Automatic laboratory declination of nondiarrheal stools submitted for CDI testing resulted in a sustained decrease in the number of specimens tested, resulting in significant laboratory and patient cost savings. Despite multiple educational efforts, no sustained changes in physician ordering practices were observed. Copyright © 2016 by the American Academy of Pediatrics.

Integrated Data Collection Analysis (IDCA) Program - Statistical Analysis of RDX Standard Data Sets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sandstrom, Mary M.; Brown, Geoffrey W.; Preston, Daniel N.

2015-10-30

The Integrated Data Collection Analysis (IDCA) program is conducting a Proficiency Test for Small- Scale Safety and Thermal (SSST) testing of homemade explosives (HMEs). Described here are statistical analyses of the results for impact, friction, electrostatic discharge, and differential scanning calorimetry analysis of the RDX Type II Class 5 standard. The material was tested as a well-characterized standard several times during the proficiency study to assess differences among participants and the range of results that may arise for well-behaved explosive materials. The analyses show that there are detectable differences among the results from IDCA participants. While these differences are statisticallymore » significant, most of them can be disregarded for comparison purposes to assess potential variability when laboratories attempt to measure identical samples using methods assumed to be nominally the same. The results presented in this report include the average sensitivity results for the IDCA participants and the ranges of values obtained. The ranges represent variation about the mean values of the tests of between 26% and 42%. The magnitude of this variation is attributed to differences in operator, method, and environment as well as the use of different instruments that are also of varying age. The results appear to be a good representation of the broader safety testing community based on the range of methods, instruments, and environments included in the IDCA Proficiency Test.« less

External quality assurance of HER2 fluorescence in situ hybridisation testing: results of a UK NEQAS pilot scheme

PubMed Central

Bartlett, John M S; Ibrahim, Merdol; Jasani, Bharat; Morgan, John M; Ellis, Ian; Kay, Elaine; Magee, Hilary; Barnett, Sarah; Miller, Keith

2007-01-01

Background and Aims Trastuzumab provides clinical benefit for advanced and early breast cancer patients whose tumours over‐express or have gene amplification of the HER2 oncogene. The UK National External Quality Assessment Scheme (NEQAS) for immunohistochemical testing was established to assess and improve the quality of HER2 immunohistochemical testing. However, until recently, no provision was available for HER2 fluorescence in situ hybridisation (FISH) testing. A pilot scheme was set up to review the performance of FISH testing in clinical diagnostic laboratories. Methods FISH was performed in 6 reference and 31 participating laboratories using a cell line panel with known HER2 status. Results Using results from reference laboratories as a criterion for acceptable performance, 60% of all results returned by participants were appropriate and 78% either appropriate or acceptable. However, 22.4% of results returned were deemed inappropriate, including 13 cases (4.2%) where a misdiagnosis would have been made had these been clinical specimens. Conclusions The results of three consecutive runs show that both reference laboratories and a proportion of routine clinical diagnostic (about 25%) centres can consistently achieve acceptable quality control of HER2 testing. Data from a significant proportion of participating laboratories show that further steps are required, including those taken via review of performance under schemes such as NEQAS, to improve quality of HER2 testing by FISH in the “real world”. PMID:16963466

Ethical issues in neurogenetics.

PubMed

Uhlmann, Wendy R; Roberts, J Scott

2018-01-01

Many neurogenetic conditions are inherited and therefore diagnosis of a patient will have implications for the patient's relatives and can raise ethical issues. Predictive genetic testing offers asymptomatic relatives the opportunity to determine their risk status for a neurogenetic condition, and professional guidelines emphasize patients' autonomy and informed, voluntary decision making. Beneficence and nonmaleficence both need to be considered when making decisions about disclosure and nondisclosure of genetic information and test results. There can be disclosure concerns and challenges in determining whose autonomy to prioritize when a patient makes a genetic testing decision that can reveal the genetic status of a relative (e.g., testing an adult child when the at-risk parent has not been tested). Ethical issues are prominent when genetic testing for neurogenetic conditions is requested prenatally, on minors, adoptees, adult children at 25% risk, and for individuals with psychiatric issues or cognitive impairment. Neurogenetic conditions can result in cognitive decline which can affect decisional capacity and lead to ethical challenges with decision making, informed consent, and determining the patient's ability to comprehend test results. The ethical implications of genetic testing and emerging issues, including direct-to-consumer genetic testing, disclosure of secondary findings from genomic sequencing, and use of apolipoprotein E testing in clinical and research settings, are also discussed. Resources for information about genetic testing practice guidelines, insurance laws, and directories of genetics clinics are included. Copyright © 2018 Elsevier B.V. All rights reserved.

Ethical Issues in Neurogenetics

PubMed Central

Uhlmann, Wendy R.; Roberts, J. Scott

2018-01-01

Many neurogenetic conditions are inherited and therefore diagnosis of a patient will have implications for their relatives and can raise ethical issues. Predictive genetic testing offers asymptomatic relatives the opportunity to determine their risk status for a neurogenetic condition, and professional guidelines emphasize patients’ autonomy and informed, voluntary decision-making. Beneficence and non-maleficence both need to be considered when making decisions about disclosure and nondisclosure of genetic information and test results. There can be disclosure concerns and issues of determining whose autonomy to prioritize when a patient makes a genetic testing decision that can reveal the genetic status of a relative (e.g. testing an adult child when the at-risk parent has not been tested). Ethical issues are prominent when genetic testing for neurogenetic conditions is requested prenatally, on minors, adoptees, adult children at 25% risk, and for individuals with psychiatric issues or cognitive impairment. Neurogenetic conditions can result in cognitive decline which can affect decisional capacity and lead to ethical challenges with decision-making, informed consent and determining the patient’s ability to comprehend test results. The ethical implications of genetic testing and emerging issues, including direct-to-consumer genetic testing, disclosure of secondary findings from genomic sequencing, and use of APOE testing in clinical and research settings, are also discussed. Resources for information about genetic testing practice guidelines, insurance laws and directories of genetics clinics are included. PMID:29325614

Emergency Physicians’ Views of Direct Notification of Laboratory and Radiology Results to Patients Using the Internet: A Multisite Survey

PubMed Central

2015-01-01

Background Patients are increasingly using the Internet to communicate with health care providers and access general and personal health information. Missed test results have been identified as a critical safety issue with studies showing up to 75% of tests for emergency department (ED) patients not being followed-up. One strategy that could reduce the likelihood of important results being missed is for ED patients to have direct access to their test results. This could be achieved electronically using a patient portal tied to the hospital’s electronic medical record or accessed from the relevant laboratory information system. Patients have expressed interest in accessing test results directly, but there have been no reported studies on emergency physicians’ opinions. Objective The aim was to explore emergency physicians’ current practices of test result notification and attitudes to direct patient notification of clinically significant abnormal and normal test results. Methods A cross-sectional survey was self-administered by senior emergency physicians (site A: n=50; site B: n=39) at 2 large public metropolitan teaching hospitals in Australia. Outcome measures included current practices for notification of results (timing, methods, and responsibilities) and concerns with direct notification. Results The response rate was 69% (61/89). More than half of the emergency physicians (54%, 33/61) were uncomfortable with patients receiving direct notification of abnormal test results. A similar proportion (57%, 35/61) was comfortable with direct notification of normal test results. Physicians were more likely to agree with direct notification of normal test results if they believed it would reduce their workload (OR 5.72, 95% CI 1.14-39.76). Main concerns were that patients could be anxious (85%, 52/61), confused (92%, 56/61), and lacking in the necessary expertise to interpret their results (90%, 55/61). Conclusions Although patients’ direct access to test results could serve as a safety net reducing the likelihood of abnormal results being missed, emergency physicians’ concerns need further exploration: which results are suitable and the timing and method of direct release to patients. Methods of access, including secure Web-based patient portals with drill-down facilities providing test descriptions and result interpretations, or laboratories sending results directly to patients, need evaluation to ensure patient safety is not compromised and the processes fit with ED clinician and laboratory work practices and patient needs. PMID:25739322

The recursive maximum likelihood proportion estimator: User's guide and test results

NASA Technical Reports Server (NTRS)

Vanrooy, D. L.

1976-01-01

Implementation of the recursive maximum likelihood proportion estimator is described. A user's guide to programs as they currently exist on the IBM 360/67 at LARS, Purdue is included, and test results on LANDSAT data are described. On Hill County data, the algorithm yields results comparable to the standard maximum likelihood proportion estimator.

Apollo experience report environmental acceptance testing

NASA Technical Reports Server (NTRS)

Laubach, C. H. M.

1976-01-01

Environmental acceptance testing was used extensively to screen selected spacecraft hardware for workmanship defects and manufacturing flaws. The minimum acceptance levels and durations and methods for their establishment are described. Component selection and test monitoring, as well as test implementation requirements, are included. Apollo spacecraft environmental acceptance test results are summarized, and recommendations for future programs are presented.

2007 Nissan Altima-2351 Hybrid Electric Vehicle Battery Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tyler Gray; Chester Motloch; James Francfort

2010-01-01

The U.S. Department of Energy's (DOE) Advanced Vehicle Testing Activity (AVTA) conducts several different types of tests on hybrid electric vehicles (HEVs), including testing the HEV batteries when both the vehicles and batteries are new, and at the conclusion of 160,000 miles of on-road accelerated testing. This report documents the battery testing performed and the battery testing results for the 2007 Nissan Altima HEV, number 2351 (VIN 1N4CL21E87C172351). The battery testing was performed by the Electric Transportation Engineering Corporation (eTec). The Idaho National Laboratory and eTec conduct the AVTA for DOE’s Vehicle Technologies Program.

Electrocardiogram

MedlinePlus

... history of heart disease in the family Normal Results Normal test results include: Heart rate: 60 to ... minute Heart rhythm: Consistent and even What Abnormal Results Mean Abnormal ECG results may be a sign ...

Community noise sources and noise control issues

NASA Technical Reports Server (NTRS)

Nihart, Gene L.

1992-01-01

The topics covered include the following: community noise sources and noise control issues; noise components for turbine bypass turbojet engine (TBE) turbojet; engine cycle selection and noise; nozzle development schedule; NACA nozzle design; NACA nozzle test results; nearly fully mixed (NFM) nozzle design; noise versus aspiration rate; peak noise test results; nozzle test in the Low Speed Aeroacoustic Facility (LSAF); and Schlieren pictures of NACA nozzle.

Mobile phone messaging for communicating results of medical investigations.

PubMed

Gurol-Urganci, Ipek; de Jongh, Thyra; Vodopivec-Jamsek, Vlasta; Car, Josip; Atun, Rifat

2012-06-13

Mobile phone messaging, such as Short Message Service (SMS) and Multimedia Message Service (MMS), has rapidly grown into a mode of communication with a wide range of applications, including communicating the results from medical investigations to patients. Alternative modes of communication of results include face-to-face communication, postal messages, calls to landlines or mobile phones, through web-based health records and email. Possible advantages of mobile phone messaging include convenience to both patients and healthcare providers, reduced waiting times for health services and healthcare costs. To assess the effects of mobile phone messaging for communicating results of medical investigations, on people's healthcare-seeking behaviour and health outcomes. Secondary objectives include assessment of participants' evaluation of the intervention, direct and indirect healthcare costs and possible risks and harms associated with the intervention. We searched the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library 2009, Issue 2), MEDLINE (OvidSP) (January 1993 to June 2009), EMBASE (OvidSP) (January 1993 to June 2009), PsycINFO (OvidSP) (January 1993 to June 2009), CINAHL (EbscoHOST) (January 1993 to June 2009), LILACS (January 1993 to June 2009) and African Health Anthology (January 1993 to June 2009). We also reviewed grey literature (including trial registers) and reference lists of articles. We included randomised controlled trials (RCTs), quasi-randomised controlled trials (QRCTs), controlled before-after (CBA) studies, or interrupted time series (ITS) studies with at least three time points before and after the intervention. We included studies assessing mobile phone messaging for communicating results of medical tests, between a healthcare provider or 'treatment buddy' and patient. We only included studies in which it was possible to assess the effects of mobile phone messaging independent of other technologies or interventions.   Two review authors independently assessed all studies against the inclusion criteria, with any disagreements resolved by a third review author. Study design features, characteristics of target populations, interventions and controls, and results data were extracted by two review authors and confirmed by a third. Primary outcomes of interest were health outcomes and healthcare utilisation as a result of the intervention. We also considered patients' and providers' evaluation of the intervention, perceptions of safety, costs and potential harms or adverse effects of the intervention. We included one randomised controlled trial involving 2782 participants. The study investigated the effects of mobile phone messaging in alleviating anxiety in women waiting for prenatal biochemical screening results for Down syndrome, by providing fast reporting of results before a follow-up appointment. The study measured health outcomes using the Spielberger State-Trait Anxiety Inventory (STAI), which includes a scale (20 to 80 points, higher score indicates higher anxiety) to describe how the respondent feels at a particular moment in time (state anxiety). The study, which was at high risk of bias, found that women who had received their test result early by text message had a mean anxiety score 2.48 points lower than women who had not yet received their result (95% CI - 8.79 to 3.84). Women with a serum-negative test result receiving their result early had a mean anxiety score 5.3 points lower (95% CI - 5.99 to -4.61) than women in the control group. Women with a serum-positive test result receiving their result early by text message had a mean anxiety score 1.2 points higher (95% CI - 3.48 to 5.88) than women in the control group.The evidence was of low quality due to high risk of bias in the included study, and the fact that the evidence comes from one study only. The study did not report on other outcomes of interest, such as patient satisfaction, adverse events or cost. We found very limited evidence of low quality that communicating results of medical investigations by mobile phone messaging may make little or no difference to women's anxiety overall or in women with positive test results, but may reduce anxiety in women with negative test results. However, with only one study included in this review, this evidence is insufficient to inform recommendations at this time. More research is needed on the effectiveness and user evaluation of these interventions. In particular, more research should be conducted into the potential risks and limitations of these interventions.

Controlled induced recharge tests at Kalamazoo, Michigan

USGS Publications Warehouse

Deutsch, Morris

1962-01-01

This article discusses the results of a controlled field testing program, which indicated that definite hydraulic and other advantages may be gained from induced recharging as practiced at Kalamazoo, Michigan. Results include the following: water levels and artesian pressures can be maintained at high stages, the results are lower pumping lifts and substantial reductions in the amount of power used for pumping; the high water levels permit increased rates of withdrawal during periods of peak demand; encroachment of poor quality water from other aquifers is minimized; the surface water induced into the aquifer is filtered naturally through great thicknesses of earth materials; natural underground storage is used to conserve and protect water, which otherwise would flow largely to waste; and, significant supplemental benefits, including flood control, have been derived. The tests demonstrated that it is possible to manipulate the regimen of a complex hydrologic system for definite hydraulic benefits with predictable results. Furthermore with current methods, quantitative evaluations may be made of the effects of induced recharge. The results of the tests, therefore, are applicable in other areas of similar hydrogeologic environments.

The Relevance of External Quality Assessment for Molecular Testing for ALK Positive Non-Small Cell Lung Cancer: Results from Two Pilot Rounds Show Room for Optimization

PubMed Central

Tembuyser, Lien; Tack, Véronique; Zwaenepoel, Karen; Pauwels, Patrick; Miller, Keith; Bubendorf, Lukas; Kerr, Keith; Schuuring, Ed; Thunnissen, Erik; Dequeker, Elisabeth M. C.

2014-01-01

Background and Purpose Molecular profiling should be performed on all advanced non-small cell lung cancer with non-squamous histology to allow treatment selection. Currently, this should include EGFR mutation testing and testing for ALK rearrangements. ROS1 is another emerging target. ALK rearrangement status is a critical biomarker to predict response to tyrosine kinase inhibitors such as crizotinib. To promote high quality testing in non-small cell lung cancer, the European Society of Pathology has introduced an external quality assessment scheme. This article summarizes the results of the first two pilot rounds organized in 2012–2013. Materials and Methods Tissue microarray slides consisting of cell-lines and resection specimens were distributed with the request for routine ALK testing using IHC or FISH. Participation in ALK FISH testing included the interpretation of four digital FISH images. Results Data from 173 different laboratories was obtained. Results demonstrate decreased error rates in the second round for both ALK FISH and ALK IHC, although the error rates were still high and the need for external quality assessment in laboratories performing ALK testing is evident. Error rates obtained by FISH were lower than by IHC. The lowest error rates were observed for the interpretation of digital FISH images. Conclusion There was a large variety in FISH enumeration practices. Based on the results from this study, recommendations for the methodology, analysis, interpretation and result reporting were issued. External quality assessment is a crucial element to improve the quality of molecular testing. PMID:25386659

Emergency physicians' views of direct notification of laboratory and radiology results to patients using the Internet: a multisite survey.

PubMed

Callen, Joanne; Giardina, Traber Davis; Singh, Hardeep; Li, Ling; Paoloni, Richard; Georgiou, Andrew; Runciman, William B; Westbrook, Johanna I

2015-03-04

Patients are increasingly using the Internet to communicate with health care providers and access general and personal health information. Missed test results have been identified as a critical safety issue with studies showing up to 75% of tests for emergency department (ED) patients not being followed-up. One strategy that could reduce the likelihood of important results being missed is for ED patients to have direct access to their test results. This could be achieved electronically using a patient portal tied to the hospital's electronic medical record or accessed from the relevant laboratory information system. Patients have expressed interest in accessing test results directly, but there have been no reported studies on emergency physicians' opinions. The aim was to explore emergency physicians' current practices of test result notification and attitudes to direct patient notification of clinically significant abnormal and normal test results. A cross-sectional survey was self-administered by senior emergency physicians (site A: n=50; site B: n=39) at 2 large public metropolitan teaching hospitals in Australia. Outcome measures included current practices for notification of results (timing, methods, and responsibilities) and concerns with direct notification. The response rate was 69% (61/89). More than half of the emergency physicians (54%, 33/61) were uncomfortable with patients receiving direct notification of abnormal test results. A similar proportion (57%, 35/61) was comfortable with direct notification of normal test results. Physicians were more likely to agree with direct notification of normal test results if they believed it would reduce their workload (OR 5.72, 95% CI 1.14-39.76). Main concerns were that patients could be anxious (85%, 52/61), confused (92%, 56/61), and lacking in the necessary expertise to interpret their results (90%, 55/61). Although patients' direct access to test results could serve as a safety net reducing the likelihood of abnormal results being missed, emergency physicians' concerns need further exploration: which results are suitable and the timing and method of direct release to patients. Methods of access, including secure Web-based patient portals with drill-down facilities providing test descriptions and result interpretations, or laboratories sending results directly to patients, need evaluation to ensure patient safety is not compromised and the processes fit with ED clinician and laboratory work practices and patient needs.

Atmospheric Probe Model: Construction and Wind Tunnel Tests

NASA Technical Reports Server (NTRS)

Vogel, Jerald M.

1998-01-01

The material contained in this document represents a summary of the results of a low speed wind tunnel test program to determine the performance of an atmospheric probe at low speed. The probe configuration tested consists of a 2/3 scale model constructed from a combination of hard maple wood and aluminum stock. The model design includes approximately 130 surface static pressure taps. Additional hardware incorporated in the baseline model provides a mechanism for simulating external and internal trailing edge split flaps for probe flow control. Test matrix parameters include probe side slip angle, external/internal split flap deflection angle, and trip strip applications. Test output database includes surface pressure distributions on both inner and outer annular wings and probe center line velocity distributions from forward probe to aft probe locations.

Physical and chemical test results of electrostatic safe flooring materials

NASA Technical Reports Server (NTRS)

Gompf, R. H.

1988-01-01

This test program was initiated because a need existed at the Kennedy Space Center (KSC) to have this information readily available to the engineer who must make the choice of which electrostatic safe floor to use in a specific application. The information, however, should be of value throughout both the government and private industry in the selection of a floor covering material. Included are the test results of 18 floor covering materials which by test evaluation at KSC are considered electrostatically safe. Tests were done and/or the data compiled in the following areas: electrostatics, flammability, hypergolic compatibility, outgassing, floor type, material thickness, and available colors. Each section contains the test method used to gather the data and the test results.

Frontal Lobe Function and Risk of Hip Fracture in Patient With Alzheimer Disease: An Analysis of Linked Data.

PubMed

Roh, Hyun Woong; Hong, Chang Hyung; Lee, SooJin; Lee, Yunhwan; Lee, Kang Soo; Chang, Ki Jung; Oh, Byoung Hoon; Choi, Seong Hye; Kim, Seong Yoon; Back, Joung Hwan; Chung, Young Ki; Lim, Ki Young; Noh, Jai Sung; Son, Sang Joon

2015-11-01

To determine the association between frontal lobe function and risk of hip fracture in patients with Alzheimer disease (AD).Retrospective cohort study using multicenter hospital-based dementia registry and national health insurance claim data was done. Participants who had available data of neuropsychological test, national health insurance claim, and other covariates were included. A total of 1660 patients with AD were included based on Stroop Test results. A total of 1563 patients with AD were included based on the Controlled Oral Word Association Test (COWAT) results. Hip fracture was measured by validated identification criteria using national health insurance claim data. Frontal lobe function was measured by Stroop Test and COWAT at baseline.After adjusting for potential covariates, including cognitive function in other domains (language, verbal and nonverbal memory, and attention), the Cox proportional hazard regression analysis revealed that risk of a hip fracture was decreased with a hazard ratio (HR) of 0.98 per one point of increase in the Stroop Test (adjusted HR = 0.98, 95% confidence interval [CI]: 0.97-1.00) and 0.93 per one point increase in COWAT (adjusted HR = 0.93, 95% CI: 0.88-0.99).The risk of hip fracture in AD patients was associated with baseline frontal lobe function. The result of this research presents evidence of association between frontal lobe function and risk of hip fracture in patients with AD.

Frontal Lobe Function and Risk of Hip Fracture in Patient With Alzheimer Disease

PubMed Central

Roh, Hyun Woong; Hong, Chang Hyung; Lee, SooJin; Lee, Yunhwan; Lee, Kang Soo; Chang, Ki Jung; Oh, Byoung Hoon; Choi, Seong Hye; Kim, Seong Yoon; Back, Joung Hwan; Chung, Young Ki; Lim, Ki Young; Noh, Jai Sung; Son, Sang Joon

2015-01-01

Abstract To determine the association between frontal lobe function and risk of hip fracture in patients with Alzheimer disease (AD). Retrospective cohort study using multicenter hospital-based dementia registry and national health insurance claim data was done. Participants who had available data of neuropsychological test, national health insurance claim, and other covariates were included. A total of 1660 patients with AD were included based on Stroop Test results. A total of 1563 patients with AD were included based on the Controlled Oral Word Association Test (COWAT) results. Hip fracture was measured by validated identification criteria using national health insurance claim data. Frontal lobe function was measured by Stroop Test and COWAT at baseline. After adjusting for potential covariates, including cognitive function in other domains (language, verbal and nonverbal memory, and attention), the Cox proportional hazard regression analysis revealed that risk of a hip fracture was decreased with a hazard ratio (HR) of 0.98 per one point of increase in the Stroop Test (adjusted HR = 0.98, 95% confidence interval [CI]: 0.97–1.00) and 0.93 per one point increase in COWAT (adjusted HR = 0.93, 95% CI: 0.88–0.99). The risk of hip fracture in AD patients was associated with baseline frontal lobe function. The result of this research presents evidence of association between frontal lobe function and risk of hip fracture in patients with AD. PMID:26559259

Usability test of KNRC self-feeding robot.

PubMed

Song, Won-Kyung; Song, Won-Jin; Kim, Yale; Kim, Jongbae

2013-06-01

Various assistive robots for supporting the activities of daily living have been developed. However, not many of these have been introduced into the market because they were found to be impractical in actual scenarios. In this paper, we report on the usability test results of an assistive robot designed for self-feeding for people having disabilities, which includes those having spinal cord injury, cerebral palsy, and traumatic brain injury. First, we present three versions of a novel self-feeding robot (KNRC self-feeding robot), which is suitable for use with Korean food, including sticky rice. These robots have been improved based on participatory action design over a period of three years. Next, we discuss the usability tests of the KNRC self-feeding robots. People with disabilities participated in comparative tests between the KNRC self-feeding robot and the commercialized product named My Spoon. The KNRC self-feeding robot showed positive results in relation to satisfaction and performance compared to the commercialized robot when users ate Korean food, including sticky rice.

High-Speed Research: 1994 Sonic Boom Workshop. Configuration, Design, Analysis and Testing

NASA Technical Reports Server (NTRS)

McCurdy, David A. (Editor)

1999-01-01

The third High-Speed Research Sonic Boom Workshop was held at NASA Langley Research Center on June 1-3, 1994. The purpose of this workshop was to provide a forum for Government, industry, and university participants to present and discuss progress in their research. The workshop was organized into sessions dealing with atmospheric propagation; acceptability studies; and configuration design, and testing. Attendance at the workshop was by invitation only. The workshop proceedings include papers on design, analysis, and testing of low-boom high-speed civil transport configurations and experimental techniques for measuring sonic booms. Significant progress is noted in these areas in the time since the previous workshop a year earlier. The papers include preliminary results of sonic boom wind tunnel tests conducted during 1993 and 1994 on several low-boom designs. Results of a mission performance analysis of all low-boom designs are also included. Two experimental methods for measuring near-field signatures of airplanes in flight are reported.

Enhancing graphical literacy skills in the high school science classroom via authentic, intensive data collection and graphical representation exposure

NASA Astrophysics Data System (ADS)

Palmeri, Anthony

This research project was developed to provide extensive practice and exposure to data collection and data representation in a high school science classroom. The student population engaged in this study included 40 high school sophomores enrolled in two microbiology classes. Laboratory investigations and activities were deliberately designed to include quantitative data collection that necessitated organization and graphical representation. These activities were embedded into the curriculum and conducted in conjunction with the normal and expected course content, rather than as a separate entity. It was expected that routine practice with graph construction and interpretation would result in improved competency when graphing data and proficiency in analyzing graphs. To objectively test the effectiveness in achieving this goal, a pre-test and post-test that included graph construction, interpretation, interpolation, extrapolation, and analysis was administered. Based on the results of a paired T-Test, graphical literacy was significantly enhanced by extensive practice and exposure to data representation.

Integrated Advanced Microwave Sounding Unit-A (AMSU-A. Engineering Report: Electromagnetic Interface (EMI)/Electromagnetic Radiation (EMR) and Electromagnetic Compatibility (EMC), for the METSAT/METOP AMSU-A1

NASA Technical Reports Server (NTRS)

Valdez, A.

1999-01-01

This document contains the procedure and the test results of the Advanced Microwave Sounding Unit-A (AMSU-A) Electromagnetic Interference (EMI), Electromagnetic Susceptibility, and Electromagnetic Compatibility (EMC) qualification test for the Meteorological Satellite (METSAT) and the Meteorological Operation Platform (METOP) projects. The test was conducted in accordance with the approved EMI/EMC Test Plan/Procedure, Specification number AE-26151/5D. This document describes the EMI/EMC test performed by Aerojet and it is presented in the following manner: Section-1 contains introductory material and a brief summary of the test results. Section 2 contains more detailed descriptions of the test plan, test procedure, and test results for each type of EMI/EMC test conducted. Section 3 contains supplementary information that includes test data sheets, plots, and calculations collected during the qualification testing.

Validation of the OECD reproduction test guideline with the New Zealand mudsnail Potamopyrgus antipodarum using trenbolone and prochloraz.

PubMed

Geiß, Cornelia; Ruppert, Katharina; Askem, Clare; Barroso, Carlos; Faber, Daniel; Ducrot, Virginie; Holbech, Henrik; Hutchinson, Thomas H; Kajankari, Paula; Kinnberg, Karin Lund; Lagadic, Laurent; Matthiessen, Peter; Morris, Steve; Neiman, Maurine; Penttinen, Olli-Pekka; Sanchez-Marin, Paula; Teigeler, Matthias; Weltje, Lennart; Oehlmann, Jörg

2017-04-01

The Organisation for Economic Cooperation and Development (OECD) provides several standard test methods for the environmental hazard assessment of chemicals, mainly based on primary producers, arthropods, and fish. In April 2016, two new test guidelines with two mollusc species representing different reproductive strategies were approved by OECD member countries. One test guideline describes a 28-day reproduction test with the parthenogenetic New Zealand mudsnail Potamopyrgus antipodarum. The main endpoint of the test is reproduction, reflected by the embryo number in the brood pouch per female. The development of a new OECD test guideline involves several phases including inter-laboratory validation studies to demonstrate the robustness of the proposed test design and the reproducibility of the test results. Therefore, a ring test of the reproduction test with P. antipodarum was conducted including eight laboratories with the test substances trenbolone and prochloraz and results are presented here. Most laboratories could meet test validity criteria, thus demonstrating the robustness of the proposed test protocol. Trenbolone did not have an effect on the reproduction of the snails at the tested concentration range (nominal: 10-1000 ng/L). For prochloraz, laboratories produced similar EC 10 and NOEC values, showing the inter-laboratory reproducibility of results. The average EC 10 and NOEC values for reproduction (with coefficient of variation) were 26.2 µg/L (61.7%) and 29.7 µg/L (32.9%), respectively. This ring test shows that the mudsnail reproduction test is a well-suited tool for use in the chronic aquatic hazard and risk assessment of chemicals.

42 CFR 486.344 - Condition: Evaluation and management of potential donors and organ placement and recovery.

Code of Federal Regulations, 2013 CFR

2013-10-01

... potential donor (including point-of-care testing and blood typing) are conducted by a laboratory that is... chapter. (3) Ensure that the potential donor's blood is typed using two separate blood samples. (4) Document potential donor's record with all test results, including blood type, before organ recovery. (d...

42 CFR 486.344 - Condition: Evaluation and management of potential donors and organ placement and recovery.

Code of Federal Regulations, 2012 CFR

2012-10-01

... potential donor (including point-of-care testing and blood typing) are conducted by a laboratory that is... chapter. (3) Ensure that the potential donor's blood is typed using two separate blood samples. (4) Document potential donor's record with all test results, including blood type, before organ recovery. (d...

42 CFR 486.344 - Condition: Evaluation and management of potential donors and organ placement and recovery.

Code of Federal Regulations, 2014 CFR

2014-10-01

... potential donor (including point-of-care testing and blood typing) are conducted by a laboratory that is... chapter. (3) Ensure that the potential donor's blood is typed using two separate blood samples. (4) Document potential donor's record with all test results, including blood type, before organ recovery. (d...

Riveting in metal airplane construction. Part III : strength of riveted joints in duralumin (continued)

NASA Technical Reports Server (NTRS)

Pleines, Wilhelm

1930-01-01

This report includes strength of riveted joints in duralumin, descriptions of test procedure and results of tests. Tabulated data includes: curshing strength by failure for various conditions, shearing strength of hole edge zone in direction of tearing, tearing strengths of plates weakened by rivet holes, and enlargement of holes at beginning of break.

Vision, Training Hours, and Road Testing Results in Bioptic Drivers

PubMed Central

Dougherty, Bradley E.; Flom, Roanne E.; Bullimore, Mark A.; Raasch, Thomas W.

2015-01-01

Purpose Bioptic telescopic spectacles (BTS) can be used by people with central visual acuity that does not meet the state standards to obtain an unrestricted driver’s license. The purpose of this study was to examine the relationships among visual and demographic factors, training hours, and the results of road testing for bioptic drivers. Methods A retrospective study of patients who received an initial daylight bioptic examination at the Ohio State University and subsequently received a bioptic license was conducted. Data were collected on vision including visual acuity, contrast sensitivity, and visual field. Hours of driver training and results of Highway Patrol road testing were extracted from records. Relationships among vision, training hours, and road testing were analyzed. Results Ninety-seven patients who completed a vision examination between 2004 and 2008 and received daylight licensure with BTS were included. Results of the first Highway Patrol road test were available for 74 patients. The median interquartile range (IQR) hours of training prior to road testing was 21±17 hours, (range of 9 to 75 hours). Candidates without previous licensure were younger (p< 0.001) and had more documented training (p< 0.001). Lack of previous licensure and more training were significantly associated with having failed a portion of the Highway Patrol test and points deducted on the road test. Conclusions New bioptic drivers without previous non-bioptic driving experience required more training and performed more poorly on road testing for licensure than those who had previous non-bioptic licensure. No visual factor was predictive of road testing results after adjustment for previous experience. The hours of training received remained predictive of road testing outcome even with adjustment for previous experience. These results suggest that previous experience and trainer assessments should be investigated as potential predictors of road safety in bioptic drivers in future studies. PMID:25946098

Evidence synthesis to inform model-based cost-effectiveness evaluations of diagnostic tests: a methodological review of health technology assessments.

PubMed

Shinkins, Bethany; Yang, Yaling; Abel, Lucy; Fanshawe, Thomas R

2017-04-14

Evaluations of diagnostic tests are challenging because of the indirect nature of their impact on patient outcomes. Model-based health economic evaluations of tests allow different types of evidence from various sources to be incorporated and enable cost-effectiveness estimates to be made beyond the duration of available study data. To parameterize a health-economic model fully, all the ways a test impacts on patient health must be quantified, including but not limited to diagnostic test accuracy. We assessed all UK NIHR HTA reports published May 2009-July 2015. Reports were included if they evaluated a diagnostic test, included a model-based health economic evaluation and included a systematic review and meta-analysis of test accuracy. From each eligible report we extracted information on the following topics: 1) what evidence aside from test accuracy was searched for and synthesised, 2) which methods were used to synthesise test accuracy evidence and how did the results inform the economic model, 3) how/whether threshold effects were explored, 4) how the potential dependency between multiple tests in a pathway was accounted for, and 5) for evaluations of tests targeted at the primary care setting, how evidence from differing healthcare settings was incorporated. The bivariate or HSROC model was implemented in 20/22 reports that met all inclusion criteria. Test accuracy data for health economic modelling was obtained from meta-analyses completely in four reports, partially in fourteen reports and not at all in four reports. Only 2/7 reports that used a quantitative test gave clear threshold recommendations. All 22 reports explored the effect of uncertainty in accuracy parameters but most of those that used multiple tests did not allow for dependence between test results. 7/22 tests were potentially suitable for primary care but the majority found limited evidence on test accuracy in primary care settings. The uptake of appropriate meta-analysis methods for synthesising evidence on diagnostic test accuracy in UK NIHR HTAs has improved in recent years. Future research should focus on other evidence requirements for cost-effectiveness assessment, threshold effects for quantitative tests and the impact of multiple diagnostic tests.

Evaluation of the impact of lime softening waste disposal in natural environments.

PubMed

Blaisi, Nawaf I; Roessler, Justin; Cheng, Weizhi; Townsend, Timothy; Al-Abed, Souhail R

2015-09-01

Drinking water treatment residues (WTR), generated from the lime softening processes, are commonly reused or disposed of in a number of applications; these include use as a soil amendment or a subsurface fill. Recently questions were posed by the Florida regulatory community on whether lime WTR that contained a small percentage of other treatment additives could appropriately be characterized as lime WTR, in terms of total element content and leachability. A study was done using a broad range of leaching tests, including a framework of tests recently adopted by the United States-Environmental Protection Agency (EPA) and tests that were modified to account for scenario specific conditions, such as the presence of natural organic matter (NOM). The results of these additional leaching tests demonstrated that certain applications, including disposal in a water body with NOM or in placement anaerobic environment, did result in increased leaching of elements such as Fe, and that a site specific assessment should be conducted prior to using WTR in these types of applications. This study illustrates the importance of leaching test selection when attempting to provide an estimation of release in practice. Although leaching tests are just one component in a beneficial use assessment and other factors including aquifer and soil properties play a significant role in the outcome, leaching tests should be tailored to most appropriately represent the scenario or reuse application being evaluated. Copyright © 2015 Elsevier Ltd. All rights reserved.

Environmental Testing of the NEXT PM1R Ion Engine

NASA Technical Reports Server (NTRS)

Snyder, John S.; Anderson, John R.; VanNoord, Jonathan L.; Soulas, George C.

2007-01-01

The NEXT propulsion system is an advanced ion propulsion system presently under development that is oriented towards robotic exploration of the solar system using solar electric power. The subsystem includes an ion engine, power processing unit, feed system components, and thruster gimbal. The Prototype Model engine PM1 was subjected to qualification-level environmental testing in 2006 to demonstrate compatibility with environments representative of anticipated mission requirements. Although the testing was largely successful, several issues were identified including the fragmentation of potting cement on the discharge and neutralizer cathode heater terminations during vibration which led to abbreviated thermal testing, and generation of particulate contamination from manufacturing processes and engine materials. The engine was reworked to address most of these findings, renamed PM1R, and the environmental test sequence was repeated. Thruster functional testing was performed before and after the vibration and thermal-vacuum tests. Random vibration testing, conducted with the thruster mated to the breadboard gimbal, was executed at 10.0 Grms for 2 min in each of three axes. Thermal-vacuum testing included three thermal cycles from 120 to 215 C with hot engine re-starts. Thruster performance was nominal throughout the test program, with minor variations in a few engine operating parameters likely caused by facility effects. There were no significant changes in engine performance as characterized by engine operating parameters, ion optics performance measurements, and beam current density measurements, indicating no significant changes to the hardware as a result of the environmental testing. The NEXT PM1R engine and the breadboard gimbal were found to be well-designed against environmental requirements based on the results reported herein. The redesigned cathode heater terminations successfully survived the vibration environments. Based on the results of this test program and confidence in the engineering solutions available for the remaining findings of the first test program, specifically the particulate contamination, the hardware environmental qualification program can proceed with confidence

Physiological Capacities: Estimating an Athlete's Potential.

ERIC Educational Resources Information Center

Lemon, Peter W. R.

1982-01-01

Several simple performance tests are described for assessing an athlete's major energy-producing capabilities. The tests are suitable for mass screening because they are easy to administer, require no sophisticated equipment, and can be done quickly. Information for evaluating test results is included. (PP)

A Simple Alternative to the IMViC Test in Microbiology.

ERIC Educational Resources Information Center

Benathen, Isaiah A.

1992-01-01

Presents a singular alternative to the Indole Methyl-red Voges-Proskauer Citrate (IMViC) test that uses bile-esculin agar to distinguish between the Escherichia coli and Enterobacter aerogenes bacteria. Includes materials and methods, results, and conclusions for the test. (MDH)

Aerothermodynamic Testing of Aerocapture and Planetary Probe Geometries in Hypersonic Ballistic-Range Environments

NASA Technical Reports Server (NTRS)

Wilder, M. C.; Reda, D. C.; Bogdanoff, D. W.; Olejniczak, J.

2005-01-01

A viewgraph presentation on aerothermodynamic testing of aerocapture and planetary probe design methods in hypersonic ballistic range environments is shown. The topics include: 1) Ballistic Range Testing; 2) NASA-Ames Hypervelocity Free Flight Facility; and 3) Representative Results.

Train-to-train impact test : occupant protection experiments

DOT National Transportation Integrated Search

2002-11-17

This paper describes the results of the occupant protection experiments included as part of the train-to-train impact test conducted at the Transportation Technology Center in Pueblo, Colorado on January 31, 2002. In this test, a cab car-led train, i...

Anomalous Thrust Production from an RF Test Device Measured on a Low-Thrust Torsion Pendulum

NASA Technical Reports Server (NTRS)

Brady, David; White, Harold G.; March, Paul; Lawrence, James T.; Davies, Frank J.

2014-01-01

This paper describes the eight-day August 2013 test campaign designed to investigate and demonstrate viability of using classical magnetoplasmadynamics to obtain a propulsive momentum transfer via the quantum vacuum virtual plasma. This paper will not address the physics of the quantum vacuum plasma thruster, but instead will describe the test integration, test operations, and the results obtained from the test campaign. Approximately 30-50 micro-Newtons of thrust were recorded from an electric propulsion test article consisting primarily of a radio frequency (RF) resonant cavity excited at approximately 935 megahertz. Testing was performed on a low-thrust torsion pendulum that is capable of detecting force at a single-digit micronewton level, within a stainless steel vacuum chamber with the door closed but at ambient atmospheric pressure. Several different test configurations were used, including two different test articles as well as a reversal of the test article orientation. In addition, the test article was replaced by an RF load to verify that the force was not being generated by effects not associated with the test article. The two test articles were designed by Cannae LLC of Doylestown, Pennsylvania. The torsion pendulum was designed, built, and operated by Eagleworks Laboratories at the NASA Johnson Space Center of Houston, Texas. Approximately six days of test integration were required, followed by two days of test operations, during which, technical issues were discovered and resolved. Integration of the two test articles and their supporting equipment was performed in an iterative fashion between the test bench and the vacuum chamber. In other words, the test article was tested on the bench, then moved to the chamber, then moved back as needed to resolve issues. Manual frequency control was required throughout the test. Thrust was observed on both test articles, even though one of the test articles was designed with the expectation that it would not produce thrust. Specifically, one test article contained internal physical modifications that were designed to produce thrust, while the other did not (with the latter being referred to as the "null" test article). Test data gathered includes torsion pendulum displacement measurements which are used to calculate generated force, still imagery in the visible spectrum to document the physical configuration, still imagery in the infrared spectrum to characterize the thermal environment, and video imagery. Post-test data includes static and animated graphics produced during RF resonant cavity characterization using the COMSOL Multiphysics® software application. Excerpts from all of the above are included and discussed in this paper. Lessons learned from test integration and operations include identification of the need to replace manual control of the resonant cavity target frequency with an automated frequency control capability. Future test plans include the development of an automatic frequency control circuit. Test results indicate that the RF resonant cavity thruster design, which is unique as an electric propulsion device, is producing a force that is not attributable to any classical electromagnetic phenomenon and therefore is potentially demonstrating an interaction with the quantum vacuum virtual plasma. Future test plans include independent verification and validation at other test facilities.

Technical Evaluation Motor No. 10 (TEM-10)

NASA Technical Reports Server (NTRS)

1993-01-01

Technical Evaluation Motor No. 10 (TEM-10) was static fired on 27 Apr. 1993 at the Thiokol Corporation full-scale motor static test bay, T-24. This final test report documents the procedures, performance, and results of the static test firing of TEM-10. All observations, discussions, conclusions, and recommendations contained are final. Included is a presentation and discussion of TEM-10 performance, anomalies, and test results in concurrence with the objectives outlined in CTP-0110, Revision D, Space Shuttle Technical Evaluation Motor No. 10 (TEM-10) Static Fire Test Plan.

Module Hipot and ground continuity test results

NASA Technical Reports Server (NTRS)

Griffith, J. S.

1984-01-01

Hipot (high voltage potential) and module frame continuity tests of solar energy conversion modules intended for deployment into large arrays are discussed. The purpose of the tests is to reveal potentially hazardous voltage conditions in installed modules, and leakage currents that may result in loss of power or cause ground fault system problems, i.e., current leakage potential and leakage voltage distribution. The tests show a combined failure rate of 36% (69% when environmental testing is included). These failure rates are believed easily corrected by greater care in fabrication.

Cost and Efficacy Assessment of an Alternative Medication Compliance Urine Drug Testing Strategy.

PubMed

Doyle, Kelly; Strathmann, Frederick G

2017-02-01

This study investigates the frequency at which quantitative results provide additional clinical benefit compared to qualitative results alone. A comparison between alternative urine drug screens and conventional screens including the assessment of cost-to-payer differences, accuracy of prescription compliance or polypharmacy/substance abuse was also included. In a reference laboratory evaluation of urine specimens from across the United States, 213 urine specimens with provided prescription medication information (302 prescriptions) were analyzed by two testing algorithms: 1) conventional immunoassay screen with subsequent reflexive testing of positive results by quantitative mass spectrometry; and 2) a combined immunoassay/qualitative mass-spectrometry screen that substantially reduced the need for subsequent testing. The qualitative screen was superior to immunoassay with reflex to mass spectrometry in confirming compliance per prescription (226/302 vs 205/302), and identifying non-prescription abuse (97 vs 71). Pharmaceutical impurities and inconsistent drug metabolite patterns were detected in only 3.8% of specimens, suggesting that quantitative results have limited benefit. The percentage difference between the conventional testing algorithm and the alternative screen was projected to be 55%, and a 2-year evaluation of test utilization as a measure of test order volume follows an exponential trend for alternative screen test orders over conventional immunoassay screens that require subsequent confirmation testing. Alternative, qualitative urine drug screens provide a less expensive, faster, and more comprehensive evaluation of patient medication compliance and drug abuse. The vast majority of results were interpretable with qualitative results alone indicating a reduced need to automatically reflex to quantitation or provide quantitation for the majority of patients. This strategy highlights a successful approach using an alternative strategy for both the laboratory and physician to align clinical needs while being mindful of costs.

Canine infection with Borrelia burgdorferi, Dirofilaria immitis, Anaplasma spp. and Ehrlichia spp. in Canada, 2013-2014.

PubMed

Herrin, Brian H; Peregrine, Andrew S; Goring, Jonas; Beall, Melissa J; Little, Susan E

2017-05-19

Canine test results generated by veterinarians throughout Canada from 2013-2014 were evaluated to assess the geographical distribution of canine infection with Borrelia burgdorferi, Dirofilaria immitis, Ehrlichia spp., and Anaplasma spp. The percent positive test results of 115,636 SNAP® 4Dx® Plus tests from dogs tested were collated by province and municipality to determine the distribution of these vector-borne infections in Canada. A total of 2,844/115,636 (2.5%) dogs tested positive for antibody to B. burgdorferi. In contrast, positive test results for D. immitis antigen and antibodies to Ehrlichia spp. and Anaplasma spp. were low, with less than 0.5% of dogs testing positive for any one of these three agents nationwide. Provincial seroprevalence for antibodies to B. burgdorferi ranged from 0.5% (Saskatchewan)-15.7% (Nova Scotia); the areas of highest percent positive test results were in proximity to regions in the USA considered endemic for Lyme borreliosis, including Nova Scotia (15.7%) and Eastern Ontario (5.1%). These high endemic foci, which had significantly higher percent positive test results than the rest of the nation (P < 0.0001), were surrounded by areas of moderate to low seroprevalence in New Brunswick (3.7%), Quebec (2.8%), and the rest of Ontario (0.9%), as well as northward and westward through Manitoba (2.4%) and Saskatchewan (0.5%). Insufficient results were available from the westernmost provinces, including Alberta and British Columbia, to allow analysis. Increased surveillance of these vector-borne disease agents, especially B. burgdorferi, is important as climate, vector range, and habitat continues to change throughout Canada. Using dogs as sentinels for these pathogens can aid in recognition of the public and veterinary health threat that each pose.

Comparison of five assays for detection of Clostridium difficile toxin.

PubMed

Chapin, Kimberle C; Dickenson, Roberta A; Wu, Fongman; Andrea, Sarah B

2011-07-01

Performance characteristics of five assays for detection of Clostridium difficile toxin were compared using fresh stool samples from patients with C. difficile infection (CDI). Assays were performed simultaneously and according to the manufacturers' instructions. Patients were included in the study if they exhibited clinical symptoms consistent with CDI. Nonmolecular assays included glutamate dehydrogenase antigen tests, with positive findings followed by the Premier Toxin A and B Enzyme Immunoassay (GDH/EIA), and the C. Diff Quik Chek Complete test. Molecular assays (PCR) included the BD GeneOhm Cdiff Assay, the Xpert C. difficile test, and the ProGastro Cd assay. Specimens were considered true positive if results were positive in two or more assays. For each method, the Youden index was calculated and cost-effectiveness was analyzed. Of 81 patients evaluated, 26 (32.1%) were positive for CDI. Sensitivity of the BD GeneOhm Cdiff assay, the Xpert C. difficile test, the ProGastro Cd assay, C. Diff Quik Chek Complete test, and two-step GDH/EIA was 96.2%, 96.2%, 88.5%, 61.5%, and 42.3%, respectively. Specificity of the Xpert C. difficile test was 96.4%, and for the other four assays was 100%. Compared with nonmolecular methods, molecular methods detected 34.7% more positive specimens. Assessment of performance characteristics and cost-effectiveness demonstrated that the BD GeneOhm Cdiff assay yielded the best results. While costly, the Xpert C. difficile test required limited processing and yielded rapid results. Because of discordant results, specimen processing, and extraction equipment requirements, the ProGastro Cd assay was the least favored molecular assay. The GDH/EIA method lacked sufficient sensitivity to be recommended. Copyright © 2011 American Society for Investigative Pathology and the Association for Molecular Pathology. Published by Elsevier Inc. All rights reserved.

Paternity tests in Mexico: Results obtained in 3005 cases.

PubMed

García-Aceves, M E; Romero Rentería, O; Díaz-Navarro, X X; Rangel-Villalobos, H

2018-04-01

National and international reports regarding the paternity testing activity scarcely include information from Mexico and other Latin American countries. Therefore, we report different results from the analysis of 3005 paternity cases analyzed during a period of five years in a Mexican paternity testing laboratory. Motherless tests were the most frequent (77.27%), followed by trio cases (20.70%); the remaining 2.04% included different cases of kinship reconstruction. The paternity exclusion rate was 29.58%, higher but into the range reported by the American Association of Blood Banks (average 24.12%). We detected 65 mutations, most of them involving one-step (93.8% and the remaining were two-step mutations (6.2%) thus, we were able to estimate the paternal mutation rate for 17 different STR loci: 0.0018 (95% CI 0.0005-0.0047). Five triallelic patterns and 12 suspected null alleles were detected during this period; however, re-amplification of these samples with a different Human Identification (HID) kit confirmed the homozygous genotypes, which suggests that most of these exclusions actually are one-step mutations. HID kits with ≥20 STRs detected more exclusions, diminishing the rate of inconclusive results with isolated exclusions (<3 loci), and leading to higher paternity indexes (PI). However, the Powerplex 21 kit (20 STRs) and Powerplex Fusion kit (22 STRs) offered similar PI (p = 0.379) and average number of exclusions (PE) (p = 0.339) when a daughter was involved in motherless tests. In brief, besides to report forensic parameters from paternity tests in Mexico, results describe improvements to solve motherless paternity tests using HID kits with ≥20 STRs instead of one including 15 STRs. Copyright © 2018 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

Comparison of Five Assays for Detection of Clostridium difficile Toxin

PubMed Central

Chapin, Kimberle C.; Dickenson, Roberta A.; Wu, Fongman; Andrea, Sarah B.

2011-01-01

Performance characteristics of five assays for detection of Clostridium difficile toxin were compared using fresh stool samples from patients with C. difficile infection (CDI). Assays were performed simultaneously and according to the manufacturers' instructions. Patients were included in the study if they exhibited clinical symptoms consistent with CDI. Nonmolecular assays included glutamate dehydrogenase antigen tests, with positive findings followed by the Premier Toxin A and B Enzyme Immunoassay (GDH/EIA), and the C. Diff Quik Chek Complete test. Molecular assays (PCR) included the BD GeneOhm Cdiff Assay, the Xpert C. difficile test, and the ProGastro Cd assay. Specimens were considered true positive if results were positive in two or more assays. For each method, the Youden index was calculated and cost-effectiveness was analyzed. Of 81 patients evaluated, 26 (32.1%) were positive for CDI. Sensitivity of the BD GeneOhm Cdiff assay, the Xpert C. difficile test, the ProGastro Cd assay, C. Diff Quik Chek Complete test, and two-step GDH/EIA was 96.2%, 96.2%, 88.5%, 61.5%, and 42.3%, respectively. Specificity of the Xpert C. difficile test was 96.4%, and for the other four assays was 100%. Compared with nonmolecular methods, molecular methods detected 34.7% more positive specimens. Assessment of performance characteristics and cost-effectiveness demonstrated that the BD GeneOhm Cdiff assay yielded the best results. While costly, the Xpert C. difficile test required limited processing and yielded rapid results. Because of discordant results, specimen processing, and extraction equipment requirements, the ProGastro Cd assay was the least favored molecular assay. The GDH/EIA method lacked sufficient sensitivity to be recommended. PMID:21704273

Utility of Urinary Protein-Creatinine Ratio and Protein Content in a 24-Hour Urine Collection in Systemic Lupus Erythematosus: A Systematic Review and Meta-Analysis.

PubMed

Medina-Rosas, Jorge; Yap, Kristy S; Anderson, Melanie; Su, Jiandong; Touma, Zahi

2016-09-01

To systematically review literature on the utility of spot urinary protein-creatinine ratio (PCR) as a screening test for proteinuria and its ability to accurately measure proteinuria compared with 24-hour urine collection (24H-P) in patients with systemic lupus erythematosus (SLE). We conducted a literature search (1900-2015) for articles comparing PCR and 24H-P in SLE patients in the databases Medline, Web of Science, and Embase. Included studies and their results were critically appraised and analyzed. Thirteen studies (1,001 patients; 84.01% women) were included. Ten studies reported on Pearson's correlation (range 0.67-0.94), and 3 studies reported on Spearman's correlation (range 0.78-1.00). The meta-analysis of studies with Pearson's correlation showed a high overall correlation of 0.80 between 24H-P and PCR, yet with high heterogeneity (I(2)  = 97.2%). Correlation analysis is not sufficient to evaluate the utility of a new test against the gold standard test, and analysis on agreement is required. Seven studies reported on agreement: 3 studies analyzed concordance correlation coefficient (0.48-0.94), 3 analyzed intraclass correlation coefficient (0.66-0.95), and 1 analyzed kappa coefficient (0.58). These results confirmed that the agreement between 24H-P and PCR was inappropriate. Three studies included Bland-Altman plots, and the results also demonstrated poor agreement between both tests. The PCR has a utility as a screening test for proteinuria in SLE patients. The studies' results of 24H-P and PCR showed poor agreement between both tests, signifying that PCR should not be a substitute for the gold standard test (24H-P) to accurately measure proteinuria. © 2016, American College of Rheumatology.

10 CFR 26.183 - Medical review officer.

Code of Federal Regulations, 2012 CFR

2012-01-01

... construed as a potential conflict of interest. Examples of relationships between laboratories and MROs that... licensee's or other entity's discretion, dilute test result. This action may include, but is not limited to... physiology of the donor. (2) The MRO may only consider the results of tests of specimens that are collected...

10 CFR 26.183 - Medical review officer.

Code of Federal Regulations, 2013 CFR

2013-01-01

... construed as a potential conflict of interest. Examples of relationships between laboratories and MROs that... licensee's or other entity's discretion, dilute test result. This action may include, but is not limited to... physiology of the donor. (2) The MRO may only consider the results of tests of specimens that are collected...

10 CFR 26.183 - Medical review officer.

Code of Federal Regulations, 2014 CFR

2014-01-01

... construed as a potential conflict of interest. Examples of relationships between laboratories and MROs that... licensee's or other entity's discretion, dilute test result. This action may include, but is not limited to... physiology of the donor. (2) The MRO may only consider the results of tests of specimens that are collected...

The "Anatomy" of a Performance-Enhancing Drug Test in Sports

ERIC Educational Resources Information Center

Werner, T. C.

2012-01-01

The components of a performance-enhancing drug (PED) test in sports include sample selection, collection, establishing sample integrity, sample pretreatment, analyte detection, data evaluation, reporting results, and action taken based on the result. Undergraduate curricula generally focus on the detection and evaluation steps of an analytical…

The Space Station Photovoltaic Panels Plasma Interaction Test Program: Test plan and results

NASA Technical Reports Server (NTRS)

Nahra, Henry K.; Felder, Marian C.; Sater, Bernard L.; Staskus, John V.

1989-01-01

The Plasma Interaction Test performed on two space station solar array panels is addressed. This includes a discussion of the test requirements, test plan, experimental set-up, and test results. It was found that parasitic current collection was insignificant (0.3 percent of the solar array delivered power). The measured arcing threshold ranged from -210 to -457 V with respect to the plasma potential. Furthermore, the dynamic response of the panels showed the panel time constant to range between 1 and 5 microsec, and the panel capacitance to be between .01 and .02 microF.

The Space Station photovoltaic panels plasma interaction test program - Test plan and results

NASA Technical Reports Server (NTRS)

Nahra, Henry K.; Felder, Marian C.; Sater, Bernard L.; Staskus, John V.

1990-01-01

The plasma Interaction Test performed on two space station solar array panels is addressed. This includes a discussion of the test requirements, test plan, experimental set-up, and test results. It was found that parasitic current collection was insignificant (0.3 percent of the solar array delivered power). The measured arcing threshold ranged from -210 to -457 V with respect to the plasma potential. Furthermore, the dynamic response of the panels showed the panel time constant to range between 1 and 5 microsec, and the panel capacitance to be between .01 and .02 microF.

HIV Point-of-Care Testing in Canadian Settings: A Scoping Review.

PubMed

Minichiello, Alexa; Swab, Michelle; Chongo, Meck; Marshall, Zack; Gahagan, Jacqueline; Maybank, Allison; Hot, Aurélie; Schwandt, Michael; Gaudry, Sonia; Hurley, Oliver; Asghari, Shabnam

2017-01-01

HIV point-of-care testing (POCT) was approved for use in Canada in 2005 and provides important public health benefits by providing rapid screening results rather than sending a blood sample to a laboratory and waiting on test results. Access to test results soon after testing (or during the same visit) is believed to increase the likelihood that individuals will receive their results and improve access to confirmatory testing and linkages to care. This paper reviews the literature on the utilization of HIV POCT across Canadian provinces. We searched OVID Medline, Embase, EBM Reviews, PsycINFO, CINAHL, and 20 electronic grey literature databases. All empirical studies investigating HIV POCT programs in Canada published in French or English were included. Searches of academic databases identified a total of 6,091 records. After removing duplicates and screening for eligibility, 27 records were included. Ten studies are peer-reviewed articles, and 17 are grey literature reports. HIV POCT in Canada is both feasible and accepted by Canadians. It is preferred to conventional HIV testing (ranging from 81.1 to 97%), and users are highly satisfied with the testing process (ranging between 96 and 100%). The majority of studies demonstrate that HIV POCT is feasible, preferred, and accepted by diverse populations in Canada. Losses to follow-up and linkage rates are also good. However, more research is needed to understand how best to scale up HIV POCT in contexts that currently have very limited or no access to testing.

HIV testing in re-education through labour camps in Guangxi Autonomous Region, China (a cross-sectional survey)

PubMed Central

Yap, Lorraine; Reekie, Joanne; Liu, Wei; Chen, Yi; Wu, Zunyou; Li, Jianghong; Zhang, Lei; Wand, Handan; Donovan, Basil; Butler, Tony

2015-01-01

Objective HIV testing is mandatory in re-education-through-labour camps (laojiaosuo) in China yet no studies have reported on the process. Methods The survey response rate was 100% although 29 detainees were excluded because they were under 18 years of age. A cross-sectional face-to-face survey was conducted in three labour camps in Guangxi, located in the south-western region of China. Results Of the 755 detainees surveyed, 725 (96%) reported having a blood test in the labour camps of whom 493 (68%) thought this included an HIV test. 61 detainees self-reported they were HIV infected, their status confirmed by medical records, if available. Of these, 53 (87%) recalled receiving post-test HIV education, and 15 (25%) were currently receiving HIV antiretroviral therapy. Pretest education on HIV was provided to 233/725 (32%) detainees. The study further reports on detainees’ reactions and feelings towards non-disclosure and disclosure of their HIV test results in the labour camps. Conclusions Mandatory testing is almost universal in the labour camps although a proportion of detainees were unaware that this included an HIV test. HIV test results should be disclosed to all labour camp detainees to reduce their distress of not knowing and prevent misconceptions about their HIV status. Labour camps provide another opportunity to implement universal treatment (‘Test and Treat’) to prevent the spread of HIV. PMID:25739879

A comparison of experimental and theoretical results for leakage, pressure gradients, and rotordynamic coefficients for tapered annular gas seal

NASA Technical Reports Server (NTRS)

Elrod, D. A.; Childs, D. W.

1986-01-01

A brief review of current annular seal theory and a discussion of the predicted effect on stiffness of tapering the seal stator are presented. An outline of Nelson's analytical-computational method for determining rotordynamic coefficients for annular compressible-flow seals is included. Modifications to increase the maximum rotor speed of an existing air-seal test apparatus at Texas A&M University are described. Experimental results, including leakage, entrance-loss coefficients, pressure distributions, and normalized rotordynamic coefficients, are presented for four convergent-tapered, smooth-rotor, smooth-stator seals. A comparison of the test results shows that an inlet-to-exit clearance ratio of 1.5 to 2.0 provides the maximum direct stiffness, a clearance ratio of 2.5 provides the greatest stability, and a clearance ratio of 1.0 provides the least stability. The experimental results are compared to theoretical results from Nelson's analysis with good agreement. Test results for cross-coupled stiffness show less sensitivity of fluid prerotation than predicted.

40 CFR 1068.450 - What records must I send to EPA?

Code of Federal Regulations, 2014 CFR

2014-07-01

..., send us a written request with justification for a waiver. (e) We may post test results on publicly..., send us a report with the following information: (1) Describe any facility used to test production-line... of tests for each family. (3) Describe your test engines/equipment, including the family's...

40 CFR 1068.450 - What records must I send to EPA?

Code of Federal Regulations, 2013 CFR

2013-07-01

..., send us a written request with justification for a waiver. (e) We may post test results on publicly..., send us a report with the following information: (1) Describe any facility used to test production-line... of tests for each family. (3) Describe your test engines/equipment, including the family's...

40 CFR 1068.450 - What records must I send to EPA?

Code of Federal Regulations, 2012 CFR

2012-07-01

..., send us a written request with justification for a waiver. (e) We may post test results on publicly..., send us a report with the following information: (1) Describe any facility used to test production-line... of tests for each family. (3) Describe your test engines/equipment, including the family's...

40 CFR 75.59 - Certification, quality assurance, and quality control record provisions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... and the run average); (B) The raw data and results for all required pre-test, post-test, pre-run and...-day calibration error tests, all daily system integrity checks (Hg monitors, only), and all off-line calibration demonstrations, including any follow-up tests after corrective action: (i) Component-system...

Eddy Current, Magnetic Particle and Hardness Testing, Aviation Quality Control (Advanced): 9227.04.

ERIC Educational Resources Information Center

Dade County Public Schools, Miami, FL.

This unit of instruction includes the principles of eddy current, magnetic particle and hardness testing; standards used for analyzing test results; techniques of operating equipment; interpretation of indications; advantages and limitations of these methods of testing; care and calibration of equipment; and safety and work precautions. Motion…

Engineering evaluation of 24 channel multispectral scanner. [from flight tests

NASA Technical Reports Server (NTRS)

Lambeck, P. F.

1973-01-01

The results of flight tests to evaluate the performance of the 24 channel multispectral scanner are reported. The flight plan and test site are described along with the time response and channel registration. The gain and offset drift, and moire patterns are discussed. Aerial photographs of the test site are included.

75 FR 57200 - National Poultry Improvement Plan and Auxiliary Provisions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-20

... (ELISA) test to confirm the positive results of other serological tests. We are proposing to remove the ELISA test from this list. The ELISA test is a screening assay and should not be used to confirm... status is negative for Mycoplasma. We would amend this paragraph to include the ELISA and the official...

Psychological Correlates of College Students Referred to a Learning Needs Center.

ERIC Educational Resources Information Center

Lefebvre, R. Craig

The paper considers issues in intelligence testing of learning disabled (LD) children and adults and reviews results of psychological testing of LD students at the University of Virginia (UVA). Tests administered include neurological screening tests and personality assessments where appropriate. It is explained that the matriculating LD student is…

Readability Level of Standardized Test Items and Student Performance: The Forgotten Validity Variable

ERIC Educational Resources Information Center

Hewitt, Margaret A.; Homan, Susan P.

2004-01-01

Test validity issues considered by test developers and school districts rarely include individual item readability levels. In this study, items from a major standardized test were examined for individual item readability level and item difficulty. The Homan-Hewitt Readability Formula was applied to items across three grade levels. Results of…

Bypass control valve seal and bearing life cycle test report

NASA Technical Reports Server (NTRS)

Lundback, A. V.

1972-01-01

The operating characteristics of a bypass control valve seal and bearing life cycle tests are reported. Data from the initial assembly, leak, torque, and deflection tests are included along with the cycle life test results and conclusions. The equipment involved was to be used in the nuclear engine for the rocket vehicles program.

Historical Increase in the Number of Factors Measured by Commercial Tests of Cognitive Ability: Are We Overfactoring?

ERIC Educational Resources Information Center

Frazier, Thomas W.; Youngstrom, Eric A.

2007-01-01

A historical increase in the number of factors purportedly measured by commercial tests of cognitive ability may result from four distinct pressures including: increasingly complex models of intelligence, test publishers' desires to provide clinically useful assessment instruments with greater interpretive value, test publishers' desires to…

16 CFR § 1210.17 - Recordkeeping and reporting.

Code of Federal Regulations, 2013 CFR

2013-01-01

... tests, photograph(s) or a video tape for a single pair of children from each 100-child test panel to...), the actual surrogate lighters tested, and the results of the tests, including video tape records, if... from disclosure by the Commission, in accordance with 16 CFR 1015.18. Requests for confidentiality of...

Analyses of the dynamic docking test system for advanced mission docking system test programs. [Apollo Soyuz Test Project

NASA Technical Reports Server (NTRS)

Gates, R. M.; Williams, J. E.

1974-01-01

Results are given of analytical studies performed in support of the design, implementation, checkout and use of NASA's dynamic docking test system (DDTS). Included are analyses of simulator components, a list of detailed operational test procedures, a summary of simulator performance, and an analysis and comparison of docking dynamics and loads obtained by test and analysis.

Structural Element Testing in Support of the Design of the NASA Composite Crew Module

NASA Technical Reports Server (NTRS)

Kellas, Sotiris; Jackson, Wade C.; Thesken, John C.; Schleicher, Eric; Wagner, Perry; Kirsch, Michael T.

2012-01-01

In January 2007, the NASA Administrator and Associate Administrator for the Exploration Systems Mission Directorate chartered the NASA Engineering and Safety Center (NESC) to design, build, and test a full-scale Composite Crew Module (CCM). For the design and manufacturing of the CCM, the team adopted the building block approach where design and manufacturing risks were mitigated through manufacturing trials and structural testing at various levels of complexity. Following NASA's Structural Design Verification Requirements, a further objective was the verification of design analysis methods and the provision of design data for critical structural features. Test articles increasing in complexity from basic material characterization coupons through structural feature elements and large structural components, to full-scale structures were evaluated. This paper discusses only four elements tests three of which include joints and one that includes a tapering honeycomb core detail. For each test series included are specimen details, instrumentation, test results, a brief analysis description, test analysis correlation and conclusions.

Simulation of Acoustics for Ares I Scale Model Acoustic Tests

NASA Technical Reports Server (NTRS)

Putnam, Gabriel; Strutzenberg, Louise L.

2011-01-01

The Ares I Scale Model Acoustics Test (ASMAT) is a series of live-fire tests of scaled rocket motors meant to simulate the conditions of the Ares I launch configuration. These tests have provided a well documented set of high fidelity acoustic measurements useful for validation including data taken over a range of test conditions and containing phenomena like Ignition Over-Pressure and water suppression of acoustics. To take advantage of this data, a digital representation of the ASMAT test setup has been constructed and test firings of the motor have been simulated using the Loci/CHEM computational fluid dynamics software. Results from ASMAT simulations with the rocket in both held down and elevated configurations, as well as with and without water suppression have been compared to acoustic data collected from similar live-fire tests. Results of acoustic comparisons have shown good correlation with the amplitude and temporal shape of pressure features and reasonable spectral accuracy up to approximately 1000 Hz. Major plume and acoustic features have been well captured including the plume shock structure, the igniter pulse transient, and the ignition overpressure.

Liquid propellant thermal conditioning system test program

NASA Technical Reports Server (NTRS)

Bullard, B. R.

1972-01-01

Results are presented from more than 1500 hours of testing on a liquid hydrogen thermal conditioning unit. Test parameters included: mixer and vent flow rates; tank size; ullage volume; pressurant gas; pressurant temperature; pressure level; and heat rate. Gaseous hydrogen and helium were used as pressurants. Analytical models were developed to correlate the test data and relate the performance to that anticipated in zero gravity. Experimental and theoretical results are presented which relate the variables controlling vapor condensation at a moving interface.

Intensity measurement of automotive headlamps using a photometric vision system

NASA Astrophysics Data System (ADS)

Patel, Balvant; Cruz, Jose; Perry, David L.; Himebaugh, Frederic G.

1996-01-01

Requirements for automotive head lamp luminous intensity tests are introduced. The rationale for developing a non-goniometric photometric test system is discussed. The design of the Ford photometric vision system (FPVS) is presented, including hardware, software, calibration, and system use. Directional intensity plots and regulatory test results obtained from the system are compared to corresponding results obtained from a Ford goniometric test system. Sources of error for the vision system and goniometer are discussed. Directions for new work are identified.

Environmental testing and laser transmission results for ruggedized high power IR fiber cables

NASA Astrophysics Data System (ADS)

Busse, Lynda; Kung, Frederic; Florea, Catalin; Shaw, Brandon; Aggarwal, Ishwar; Sanghera, Jas

2013-03-01

We present successful results of high mid-IR laser power transmission as well as MIL-SPEC environmental testing (thermal cycling and vibration testing) of ruggedized, IR-transmitting chalcogenide glass fiber cables. The cables tested included chalcogenide fiber cables with endfaces imprinted with anti-reflective "moth eye" surfaces, whereby the reflection loss is reduced from about 17% per end to less than 3%. The cables with these moth eye surfaces also show excellent laser damage resistance.

Combined Space Environmental Exposure Tests of Multi-Junction GaAs/Ge Solar Array Coupons

NASA Technical Reports Server (NTRS)

Hoang, Bao; Wong, Frankie; Corey, Ron; Gardiner, George; Funderburk, Victor V.; Gahart, Richard; Wright, Kenneth H.; Schneider, Todd; Vaughn, Jason

2010-01-01

A set of multi-junction GaAs/Ge solar array test coupons were subjected to a sequence of 5-year increments of combined environmental exposure tests. The purpose of this test program is to understand the changes and degradation of the solar array panel components, including its ESD mitigation design features in their integrated form, after multiple years (up to 15) of simulated geosynchronous space environment. These tests consist of: UV radiation, electrostatic discharge (ESD), electron/proton particle radiation, thermal cycling, and ion thruster plume exposures. The solar radiation was produced using a Mercury-Xenon lamp with wavelengths in the UV spectrum ranging from 230 to 400 nm. The ESD test was performed in the inverted-gradient mode using a low-energy electron (2.6 - 6 keV) beam exposure. The ESD test also included a simulated panel coverglass flashover for the primary arc event. The electron/proton radiation exposure included both 1.0 MeV and 100 keV electron beams simultaneous with a 40 keV proton beam. The thermal cycling included simulated transient earth eclipse for satellites in geosynchronous orbit. With the increasing use of ion thruster engines on many satellites, the combined environmental test also included ion thruster exposure to determine whether solar array surface erosion had any impact on its performance. Before and after each increment of environmental exposures, the coupons underwent visual inspection under high power magnification and electrical tests that included characterization by LAPSS, Dark I-V, and electroluminescence. This paper discusses the test objective, test methodologies, and preliminary results after 5 years of simulated exposure.

Develop and test fuel cell powered on-site integrated total energy system. Phase 3: Full-scale power plant development

NASA Technical Reports Server (NTRS)

Kaufman, A.

1981-01-01

An integrated 5 kW power system based upon methanol fuel and a phosphoric acid fuel cell operating at about 473 K is described. Description includes test results of advanced fuel cell catalysts, a semiautomatic acid replenishment system and a completed 5 kW methanol/system reformer. The results of a preliminary system test on a reformer/stack/inverter combination are reported. An initial design for a 25 kW stack is presented. Experimental plans are outlined for data acquisition necessary for design of a 50 kW methanol/steam reformer. Activities related to complete mathematical modelling of the integrated power system, including wasteheat utilization, are described.

Aircraft Engine Noise Research and Testing at the NASA Glenn Research Center

NASA Technical Reports Server (NTRS)

Elliott, Dave

2015-01-01

The presentation will begin with a brief introduction to the NASA Glenn Research Center as well as an overview of how aircraft engine noise research fits within the organization. Some of the NASA programs and projects with noise content will be covered along with the associated goals of aircraft noise reduction. Topics covered within the noise research being presented will include noise prediction versus experimental results, along with engine fan, jet, and core noise. Details of the acoustic research conducted at NASA Glenn will include the test facilities available, recent test hardware, and data acquisition and analysis methods. Lastly some of the actual noise reduction methods investigated along with their results will be shown.

Device for testing continuity and/or short circuits in a cable

NASA Technical Reports Server (NTRS)

Hayhurst, Arthur R. (Inventor)

1995-01-01

A device for testing current paths is attachable to a conductor. The device automatically checks the current paths of the conductor for continuity of a center conductor, continuity of a shield and a short circuit between the shield and the center conductor. The device includes a pair of connectors and a circuit to provide for testing of the conductive paths of the cable. The pair of connectors electrically connects the conductive paths of a cable to be tested with the circuit paths of the circuit. The circuit paths in the circuit include indicators to simultaneously indicate the results of the testing.

Advanced Stirling Convertor Durability Testing: Plans and Interim Results

NASA Technical Reports Server (NTRS)

Meer, David W.; Oriti, Salvatore M.

2012-01-01

The U.S. Department of Energy (DOE), Lockheed Martin Corporation (LM), and NASA Glenn Research Center (GRC) have been developing the Advanced Stirling Radioisotope Generator (ASRG) for use as a power system for space science missions. In support of this program, GRC has been involved in testing Stirling convertors, including the Advanced Stirling Convertor (ASC), for use in the ASRG. This testing includes electromagnetic interference/compatibility (EMI/EMC), structural dynamics, advanced materials, organics, and unattended extended operation. The purpose of the durability tests is to experimentally demonstrate the margins in the ASC design. Due to the high value of the hardware, previous ASC tests focused on establishing baseline performance of the convertors within the nominal operating conditions. The durability tests present the first planned extension of the operating conditions into regions beyond those intended to meet the product spec, where the possibility exists of lateral contact, overstroke, or over-temperature events. These tests are not intended to cause damage that would shorten the life of the convertors, so they can transition into extended operation at the conclusion of the tests. This paper describes the four tests included in the durability test sequence: 1) start/stop cycling, 2) exposure to constant acceleration in the lateral and axial directions, 3) random vibration at increased piston amplitude to induce contact events, and 4) overstroke testing to simulate potential failures during processing or during the mission life where contact events could occur. The paper also summarizes the analysis and simulation used to predict the results of each of these tests.

Results of the NASP Ames Integrated Mixing Hypersonic Engine (AIMHYE) Scramjet Test Program

NASA Technical Reports Server (NTRS)

Cavolowsky, John A.; Loomis, Mark P.; Deiwert, George S.

1995-01-01

This paper describes the test techniques and results from the National Aerospace Plane Government Work Package 53, the Ames Integrated Mixing Hypersonic Engine (AIMHYE) Scramjet Test program conducted in the NASA Ames 16-Inch Combustion Driven Shock Tunnel. This was a series of near full-scale scramjet combustor tests with the objective to obtain high speed combustor and nozzle data from an engine with injector configurations similar to the NASP E21 and E22a designs. The experimental test approach was to use a large combustor model (80-100% throat height) designed and fabricated for testing in the semi-free jet mode. The conditions tested were similar to the "blue book" conditions at Mach 12, 14, and 16. GWP 53 validated use of large, long test time impulse facilities, specifically the Ames 16-Inch Shock Tunnel, for high Mach number scramjet propulsion testing an integrated test rig (inlet, combustor, and nozzle). Discussion of key features of the test program will include: effects of the 2-D combustor inlet pressure profile; performance of large injectors' fueling system that included nozzlettes, base injection, and film cooling; and heat transfer measurements to the combustor. Significant instrumentation development and application efforts include the following: combustor force balance application for measurement of combustor drag for comparison with integrated point measurements of skin friction; nozzle metric strip for measuring thrust with comparison to integrated pressure measurements; and nonintrusive optical fiber-based diode laser absorption measurements of combustion products for determination of combustor performance. Direct measurements will be reported for specific test article configurations and compared with CFD solutions.

An effective utilization management strategy by dual approach of influencing physician ordering and gate keeping.

PubMed

Elnenaei, Manal O; Campbell, Samuel G; Thoni, Andrea J; Lou, Amy; Crocker, Bryan D; Nassar, Bassam A

2016-02-01

There is increasing recognition of the importance of appropriate laboratory test utilization. We investigate the effect of a multifaceted educational approach that includes physician feedback on individual test ordering, in conjunction with targeted restriction, on the utilization of selected laboratory tests. Scientific evidence was compiled on the usefulness and limitations of tests suspected of being over utilized in our laboratories. A variety of approaches were used to deliver education on each of the targeted tests, with greater focus on primary care physicians (PCPs). Feedback on requesting behavior of these tests was also communicated to the latter group which included an educational component. Laboratory based restriction of testing was also exercised, including the unbundling of our electrolyte panel. PCP requesting patterns for the selected tests were found to be markedly skewed. The interventions implemented over the study period resulted in a substantial 51% reduction in overall ordering of five of the targeted tests equating to an annual marginal cost saving of $60,124. Unbundling of the electrolyte panel resulted in marginal cost savings that equated annually to $42,500 on chloride and $48,000 on total CO2. A multifaceted educational approach combined with feedback on utilization and laboratory driven gate-keeping significantly reduced the number of laboratory tests suspected of being redundant or unjustifiably requested. Laboratory professionals are well positioned to manage demand on laboratory tests by utilizing evidence base in developing specific test ordering directives and gate-keeping rules. Crown Copyright © 2015. Published by Elsevier Inc. All rights reserved.

Alternative Bio-Derived JP-8 Class Fuel and JP-8 Fuel: Flame Tube Combustor Test Results Compared using a GE TAPS Injector Configuration

NASA Technical Reports Server (NTRS)

Hicks, Yolanda R.; Anderson, Robert; Tedder, Sarah

2016-01-01

This paper presents results from tests in a NASA Glenn Research Center (GRC) flame tube facility, where a bio-derived alternate fuel was compared with JP-8 for emissions and general combustion performance. A research version of General Electric Aviation (GE) TAPS injector was used for the tests. Results include 2D, planar laser-based imaging as well as basic flow visualization of the flame. Four conditions were selected that simulate various engine power conditions relevant to NASA Fundamental Aeronautics Supersonics and Environmentally Responsible Aviation Projects were tested.

Diagnostic value of repeated ice tests in the evaluation of ptosis in myasthenia gravis.

PubMed

Park, Jun Young; Yang, Hee Kyung; Hwang, Jeong-Min

2017-01-01

Twenty-six patients with ptosis related to Myasthenia gravis (MG) and 38 controls with ptosis other than MG were included. All patients were tested with the ice test 2 times on separate days in the afternoon. The margin reflex distance (MRD) was measured before and immediately after 2-minute application of ice on the eyelids. The ice test was judged positive if there was an improvement of at least 2.0 mm of MRD after the ice test. Among the patients with negative test results, 'equivocal' was defined by improvement of MRD from at least 1.0 mm to less than 2.0 mm after the ice test. Repeated ice test results showed an agreement of 61.5% in MG, and 97.4% in nonmyasthenic ptosis. Repeated ice tests increased the sensitivity by 34.6% compared to a single test. Among the patients with repeatedly negative test results, 63.6% of those who showed equivocal results at least once turned out to be MG. Of those with repeated non-equivocal negative results, nobody turned out to be MG. There was no significant difference of the ice test results between ocular MG and generalized MG (p = 0.562).

Diagnostic value of repeated ice tests in the evaluation of ptosis in myasthenia gravis

PubMed Central

2017-01-01

Twenty-six patients with ptosis related to Myasthenia gravis (MG) and 38 controls with ptosis other than MG were included. All patients were tested with the ice test 2 times on separate days in the afternoon. The margin reflex distance (MRD) was measured before and immediately after 2-minute application of ice on the eyelids. The ice test was judged positive if there was an improvement of at least 2.0 mm of MRD after the ice test. Among the patients with negative test results, 'equivocal’ was defined by improvement of MRD from at least 1.0 mm to less than 2.0 mm after the ice test. Repeated ice test results showed an agreement of 61.5% in MG, and 97.4% in nonmyasthenic ptosis. Repeated ice tests increased the sensitivity by 34.6% compared to a single test. Among the patients with repeatedly negative test results, 63.6% of those who showed equivocal results at least once turned out to be MG. Of those with repeated non-equivocal negative results, nobody turned out to be MG. There was no significant difference of the ice test results between ocular MG and generalized MG (p = 0.562). PMID:28562609

Blood Gases Test

MedlinePlus

... a pH, carbon dioxide/oxygen, or electrolyte imbalance. Examples include uncontrolled diabetes , which can lead to ketoacidosis ... acid from the stomach), and sodium bicarbonate overdose. Examples of test results associated with the above conditions ...

The Psychology Experiment Building Language (PEBL) and PEBL Test Battery

PubMed Central

Mueller, Shane T.; Piper, Brian J.

2014-01-01

Background We briefly describe the Psychology Experiment Building Language (PEBL), an open source software system for designing and running psychological experiments. New Method We describe the PEBL test battery, a set of approximately 70 behavioral tests which can be freely used, shared, and modified. Included is a comprehensive set of past research upon which tests in the battery are based. Results We report the results of benchmark tests that establish the timing precision of PEBL. Comparison with Existing Method We consider alternatives to the PEBL system and battery tests. Conclusions We conclude with a discussion of the ethical factors involved in the open source testing movement. PMID:24269254

Profit-driven drug testing.

PubMed

Collen, Mark

2012-01-01

Random drug testing of people being treated for chronic pain has become more common. Physicians may drug test patients on opioid therapy as a result of concerns over prosecution, drug misuse, addiction, and overdose. However, profit motive has remained unexplored. This article suggests profits also drive physician drug-testing behavior and evidence is offered, including an exploration of Medicare reimbursement incentives and kickbacks for drug testing.

Comparative evaluation of subgrade resilient modulus from non-destructive, in-situ, and laboratory methods.

DOT National Transportation Integrated Search

2007-08-01

Field and laboratory testing programs were conducted to develop models that predict the resilient modulus of subgrade soils from : the test results of DCP, CIMCPT, FWD, Dynaflect, and soil properties. The field testing program included DCP, CIMCPT, F...

GENETIC VARIATION FOR COPPER RESISTANCE IN FATHEAD MINNOW TOXICITY TESTS

EPA Science Inventory

Unexplained variation in the results of aquatic organism toxicity tests is a consistently observed and troubling phenomenon. Possible sources of variation include differences in condition or nutritional status of the population prior to the test, as well as age, density and hand...

49 CFR 40.209 - What procedural problems do not result in the cancellation of a test and do not require correction?

Code of Federal Regulations, 2012 CFR

2012-10-01

... significant adverse effect on the right of the employee to have a fair and accurate test. Matters that do not result in the cancellation of a test include, but are not limited to, the following: (1) A minor... that does not affect employee protections under this part (e.g., the collector's failure to add bluing...

49 CFR 40.209 - What procedural problems do not result in the cancellation of a test and do not require correction?

Code of Federal Regulations, 2014 CFR

2014-10-01

... significant adverse effect on the right of the employee to have a fair and accurate test. Matters that do not result in the cancellation of a test include, but are not limited to, the following: (1) A minor... that does not affect employee protections under this part (e.g., the collector's failure to add bluing...

26 x 6.6 radial-belted aircraft tire performance

NASA Technical Reports Server (NTRS)

Davis, Pamela A.; Martinson, Veloria J.; Yager, Thomas J.; Stubbs, Sandy M.

1991-01-01

Preliminary results from testing of 26 x 6.6 radial-belted and bias-ply aircraft tires at NASA Langley's Aircraft Landing Dynamics Facility (ALDF) are reviewed. The 26 x 6.6 tire size evaluation includes cornering performance tests throughout the aircraft ground operational speed range for both dry and wet runway surfaces. Static test results to define 26 x 6.6 tire vertical stiffness properties are also presented and discussed.

A research program to reduce interior noise in general aviation airplanes. [test methods and results

NASA Technical Reports Server (NTRS)

Roskam, J.; Muirhead, V. U.; Smith, H. W.; Peschier, T. D.; Durenberger, D.; Vandam, K.; Shu, T. C.

1977-01-01

Analytical and semi-empirical methods for determining the transmission of sound through isolated panels and predicting panel transmission loss are described. Test results presented include the influence of plate stiffness and mass and the effects of pressurization and vibration damping materials on sound transmission characteristics. Measured and predicted results are presented in tables and graphs.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hart, Darren M.

Sandia National Laboratories has tested and evaluated Geotech Smart24 data acquisition system with active Fortezza crypto card data signing and authentication. The test results included in this report were in response to static and tonal-dynamic input signals. Most test methodologies used were based on IEEE Standards 1057 for Digitizing Waveform Recorders and 1241 for Analog to Digital Converters; others were designed by Sandia specifically for infrasound application evaluation and for supplementary criteria not addressed in the IEEE standards. The objective of this work was to evaluate the overall technical performance of the Geotech Smart24 digitizer with a Fortezza PCMCIA cryptomore » card actively implementing the signing of data packets. The results of this evaluation were compared to relevant specifications provided within manufacturer's documentation notes. The tests performed were chosen to demonstrate different performance aspects of the digitizer under test. The performance aspects tested include determining noise floor, least significant bit (LSB), dynamic range, cross-talk, relative channel-to-channel timing, time-tag accuracy, analog bandwidth and calibrator performance.« less

Assessment accommodations on tests of academic achievement for students who are deaf or hard of hearing: a qualitative meta-analysis of the research literature.

PubMed

Cawthon, Stephanie; Leppo, Rachel

2013-01-01

The authors conducted a qualitative meta-analysis of the research on assessment accommodations for students who are deaf or hard of hearing. There were 16 identified studies that analyzed the impact of factors related to student performance on academic assessments across different educational settings, content areas, and types of assessment accommodations. The meta-analysis found that the results of analyses of group effects of accommodated versus unaccommodated test formats are often not significant, test-level factors exist that can affect how students perceive the assessments, and differences exist in how test items function across different conditions. Student-level factors, including educational context and academic proficiency, influence accommodations' role in assessment processes. The results of this analysis highlight the complexity of and intersections between student-level factors, test-level factors, and larger policy contexts. Findings are discussed within the context of larger changes in academic assessment, including computer-based administration and high-stakes testing.

Experimental Results From a 2kW Brayton Power Conversion Unit

NASA Technical Reports Server (NTRS)

Hervol, David; Mason, Lee; Birchenough, Arthur

2003-01-01

This paper presents experimental test results from operation of a 2 kWe Brayton power conversion unit. The Brayton converter was developed for a solar dynamic power system flight experiment planned for the Mir Space Station in 1997. The flight experiment was cancelled, but the converter was tested at Glenn Research Center as part of the Solar Dynamic Ground Test Demonstration system which included a solar concentrator, heat receiver, and space radiator. In preparation for the current testing, the heat receiver was removed and replaced with an electrical resistance heater, simulating the thermal input of a steady-state nuclear source. The converter was operated over a full range of thermal input power levels and rotor speeds to generate an overall performance map. The converter unit will serve as the centerpiece of a Nuclear Electric Propulsion Testbed at Glenn. Future potential uses for the Testbed include high voltage electrical controller development, integrated electric thruster testing and advanced radiator demonstration testing to help guide high power Brayton technology development for Nuclear Electric Propulsion (NEP).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maloy, Stuart Andrew; Pestovich, Kimberly Shay; Anderoglu, Osman

The Fuel Cycle Research and Development program is investigating methods of transmuting minor actinides in various fuel cycle options. To achieve this goal, new fuels and cladding materials must be developed and tested to high burnup levels (e.g. >20%) requiring cladding to withstand very high doses (greater than 200 dpa) while in contact with the coolant and the fuel. To develop and qualify materials to a total fluence greater than 200 dpa requires development of advanced alloys and irradiations in fast reactors to test these alloys. Recent results from testing numerous ferritic/martensitic steels at low temperatures suggest that improvements inmore » low temperature radiation tolerance can be achieved through carefully controlling the nitrogen content in these alloys. Thus, four new heats of HT-9 were produced with controlled nitrogen content: two by Metalwerks and two by Sophisticated Alloys. Initial results on these new alloys are presented including microstructural analysis and hardness testing. Future testing will include irradiation testing with ions and in reactor.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rowe, M.D.; Pierce, B.L.

This report presents results of tests of different final site selection methods used for siting large-scale facilities such as nuclear power plants. Test data are adapted from a nuclear power plant siting study conducted on Long Island, New York. The purpose of the tests is to determine whether or not different final site selection methods produce different results, and to obtain some understanding of the nature of any differences found. Decision rules and weighting methods are included. Decision rules tested are Weighting Summation, Power Law, Decision Analysis, Goal Programming, and Goal Attainment; weighting methods tested are Categorization, Ranking, Rating Ratiomore » Estimation, Metfessel Allocation, Indifferent Tradeoff, Decision Analysis lottery, and Global Evaluation. Results show that different methods can, indeed, produce different results, but that the probability that they will do so is controlled by the structure of differences among the sites being evaluated. Differences in weights and suitability scores attributable to methods have reduced significance if the alternatives include one or two sites that are superior to all others in many attributes. The more tradeoffs there are among good and bad levels of different attributes at different sites, the more important are the specifics of methods to the final decision. 5 refs., 14 figs., 19 tabs.« less

Smoking and occupational allergy in workers in a platinum refinery.

PubMed Central

Venables, K. M.; Dally, M. B.; Nunn, A. J.; Stevens, J. F.; Stephens, R.; Farrer, N.; Hunter, J. V.; Stewart, M.; Hughes, E. G.; Newman Taylor, A. J.

1989-01-01

OBJECTIVE--To test the hypothesis that smoking increases the risk of sensitisation by occupational allergens. DESIGN--Historical prospective cohort study. SETTING--Platinum refinery. SUBJECTS--91 Workers (86 men) who started work between 1 January 1973 and 31 December 1974 and whose smoking habit and atopic state (on skin prick testing with common allergens) had been noted at joining. MAIN OUTCOME MEASURES--Results of skin prick tests with platinum salts carried out routinely every three to six months and records of any respiratory symptoms noted by the refinery's occupational health service. Follow up was until 1980 or until leaving refinery work, whichever was earlier. RESULTS--57 Workers smoked and 29 were atopic; 22 developed a positive result on skin testing with platinum salts and 49 developed symptoms, including all 22 whose skin test result was positive. Smoking was the only significant predictor of a positive result on skin testing with platinum salts and its effect was greater than that of atopy; the estimated relative risks (95% confidence interval) when both were included in the regression model were: smokers versus non-smokers 5.05 (1.68 to 15.2) and atopic versus non-atopic 2.29 (0.88 to 5.99). Number of cigarettes smoked per day was the only significant predictor of respiratory symptoms. CONCLUSION--Smokers are at increased risk of sensitisation by platinum salts. PMID:2508944

OPSAID Initial Design and Testing Report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hurd, Steven A.; Stamp, Jason Edwin; Chavez, Adrian R.

2007-11-01

Process Control System (PCS) security is critical to our national security. Yet, there are a number of technological, economic, and educational impediments to PCS owners implementing effective security on their systems. OPSAID (Open PCS Security Architecture for Interoperable Design), a project sponsored by the US Department of Energy's Office of Electricity Delivery and Reliability, aims to address this issue through developing and testing an open source architecture for PCS security. Sandia National Laboratories, along with a team of PCS vendors and owners, have developed and tested this PCS security architecture. This report describes their progress to date.2 AcknowledgementsThe authors acknowledgemore » and thank their colleagues for their assistance with the OPSAID project.Sandia National Laboratories: Alex Berry, Charles Perine, Regis Cassidy, Bryan Richardson, Laurence PhillipsTeumim Technical, LLC: Dave TeumimIn addition, the authors are greatly indebted to the invaluable help of the members of the OPSAID Core Team. Their assistance has been critical to the success and industry acceptance of the OPSAID project.Schweitzer Engineering Laboratory: Rhett Smith, Ryan Bradetich, Dennis GammelTelTone: Ori Artman Entergy: Dave Norton, Leonard Chamberlin, Mark AllenThe authors would like to acknowledge that the work that produced the results presented in this paper was funded by the U.S. Department of Energy/Office of Electricity Delivery and Energy Reliability (DOE/OE) as part of the National SCADA Test Bed (NSTB) Program. Executive SummaryProcess control systems (PCS) are very important for critical infrastructure and manufacturing operations, yet cyber security technology in PCS is generally poor. The OPSAID (Open PCS (Process Control System) Security Architecture for Interoperable Design) program is intended to address these security shortcomings by accelerating the availability and deployment of comprehensive security technology for PCS, both for existing PCS and inherently secure PCS in the future. All activities are closely linked to industry outreach and advisory efforts.Generally speaking, the OPSAID project is focused on providing comprehensive security functionality to PCS that communicate using IP. This is done through creating an interoperable PCS security architecture and developing a reference implementation, which is tested extensively for performance and reliability.This report first provides background on the PCS security problem and OPSAID, followed by goals and objectives of the project. The report also includes an overview of the results, including the OPSAID architecture and testing activities, along with results from industry outreach activities. Conclusion and recommendation sections follow. Finally, a series of appendices provide more detailed information regarding architecture and testing activities.Summarizing the project results, the OPSAID architecture was defined, which includes modular security functionality and corresponding component modules. The reference implementation, which includes the collection of component modules, was tested extensively and proved to provide more than acceptable performance in a variety of test scenarios. The primary challenge in implementation and testing was correcting initial configuration errors.OPSAID industry outreach efforts were very successful. A small group of industry partners were extensively involved in both the design and testing of OPSAID. Conference presentations resulted in creating a larger group of potential industry partners.Based upon experience implementing and testing OPSAID, as well as through collecting industry feedback, the OPSAID project has done well and is well received. Recommendations for future work include further development of advanced functionality, refinement of interoperability guidance, additional laboratory and field testing, and industry outreach that includes PCS owner education. 4 5 --This page intentionally left blank --« less

2011 Chevrolet Volt VIN 0815 Plug-In Hybrid Electric Vehicle Battery Test Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tyler Gray; Matthew Shirk; Jeffrey Wishart

2013-07-01

The U.S. Department of Energy (DOE) Advanced Vehicle Testing Activity (AVTA) program consists of vehicle, battery, and infrastructure testing on advanced technology related to transportation. The activity includes tests on plug-in hybrid electric vehicles (PHEVs), including testing the PHEV batteries when both the vehicles and batteries are new and at the conclusion of 12,000 miles of on-road fleet testing. This report documents battery testing performed for the 2011 Chevrolet Volt PHEV (VIN 1G1RD6E48BU100815). The battery testing was performed by the Electric Transportation Engineering Corporation (eTec) dba ECOtality North America. The Idaho National Laboratory and ECOtality North America collaborate on themore » AVTA for the Vehicle Technologies Program of the DOE.« less

Self pressuring HTP feed systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Whitehead, J.

1999-10-14

Hydrogen peroxide tanks can be pressurized with decomposed HTP (high test hydrogen peroxide) originating in the tank itself. In rocketry, this offers the advantage of eliminating bulky and heavy inert gas storage. Several prototype self-pressurizing HTP systems have recently been designed and tested. Both a differential piston tank and a small gas-driven pump have been tried to obtain the pressure boost needed for flow through a gas generator and back to the tank. Results include terrestrial maneuvering tests of a prototype microsatellite, including warm gas attitude control jets.

When the Test of Mediation is More Powerful than the Test of the Total Effect

PubMed Central

O'Rourke, Holly P.; MacKinnon, David P.

2014-01-01

Although previous research has studied power in mediation models, the extent to which the inclusion of a mediator will increase power has not been investigated. First, a study compared analytical power of the mediated effect to the total effect in a single mediator model to identify the situations in which the inclusion of one mediator increased statistical power. Results from the first study indicated that including a mediator increased statistical power in small samples with large coefficients and in large samples with small coefficients, and when coefficients were non-zero and equal across models. Next, a study identified conditions where power was greater for the test of the total mediated effect compared to the test of the total effect in the parallel two mediator model. Results indicated that including two mediators increased power in small samples with large coefficients and in large samples with small coefficients, the same pattern of results found in the first study. Finally, a study assessed analytical power for a sequential (three-path) two mediator model and compared power to detect the three-path mediated effect to power to detect both the test of the total effect and the test of the mediated effect for the single mediator model. Results indicated that the three-path mediated effect had more power than the mediated effect from the single mediator model and the test of the total effect. Practical implications of these results for researchers are then discussed. PMID:24903690

Effects of Electric Vehicle Fast Charging on Battery Life and Vehicle Performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matthew Shirk; Jeffrey Wishart

2015-04-01

As part of the U.S. Department of Energy’s Advanced Vehicle Testing Activity, four new 2012 Nissan Leaf battery electric vehicles were instrumented with data loggers and operated over a fixed on-road test cycle. Each vehicle was operated over the test route, and charged twice daily. Two vehicles were charged exclusively by AC level 2 EVSE, while two were exclusively DC fast charged with a 50 kW charger. The vehicles were performance tested on a closed test track when new, and after accumulation of 50,000 miles. The traction battery packs were removed and laboratory tested when the vehicles were new, andmore » at 10,000-mile intervals. Battery tests include constant-current discharge capacity, electric vehicle pulse power characterization test, and low peak power tests. The on-road testing was carried out through 70,000 miles, at which point the final battery tests were performed. The data collected over 70,000 miles of driving, charging, and rest are analyzed, including the resulting thermal conditions and power and cycle demands placed upon the battery. Battery performance metrics including capacity, internal resistance, and power capability obtained from laboratory testing throughout the test program are analyzed. Results are compared within and between the two groups of vehicles. Specifically, the impacts on battery performance, as measured by laboratory testing, are explored as they relate to battery usage and variations in conditions encountered, with a primary focus on effects due to the differences between AC level 2 and DC fast charging. The contrast between battery performance degradation and the effect on vehicle performance is also explored.« less

Semaphore network encryption report

NASA Astrophysics Data System (ADS)

Johnson, Karen L.

1994-03-01

This paper documents the results of a preliminary assessment performed on the commercial off-the-shelf (COTS) Semaphore Communications Corporation (SCC) Network Security System (NSS). The Semaphore NSS is a family of products designed to address important network security concerns, such as network source address authentication and data privacy. The assessment was performed in the INFOSEC Core Integration Laboratory, and its scope was product usability focusing on interoperability and system performance in an existing operational network. Included in this paper are preliminary findings. Fundamental features and functionality of the Semaphore NSS are identified, followed by details of the assessment, including test descriptions and results. A summary of test results and future plans are also included. These findings will be useful to those investigating the use of commercially available solutions to network authentication and data privacy.

Sierra/SolidMechanics 4.48 Verification Tests Manual.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Plews, Julia A.; Crane, Nathan K; de Frias, Gabriel Jose

2018-03-01

Presented in this document is a small portion of the tests that exist in the Sierra / SolidMechanics (Sierra / SM) verification test suite. Most of these tests are run nightly with the Sierra / SM code suite, and the results of the test are checked versus the correct analytical result. For each of the tests presented in this document, the test setup, a description of the analytic solution, and comparison of the Sierra / SM code results to the analytic solution is provided. Mesh convergence is also checked on a nightly basis for several of these tests. This documentmore » can be used to confirm that a given code capability is verified or referenced as a compilation of example problems. Additional example problems are provided in the Sierra / SM Example Problems Manual. Note, many other verification tests exist in the Sierra / SM test suite, but have not yet been included in this manual.« less

Sierra/SolidMechanics 4.48 Verification Tests Manual.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Plews, Julia A.; Crane, Nathan K.; de Frias, Gabriel Jose

Presented in this document is a small portion of the tests that exist in the Sierra / SolidMechanics (Sierra / SM) verification test suite. Most of these tests are run nightly with the Sierra / SM code suite, and the results of the test are checked versus the correct analytical result. For each of the tests presented in this document, the test setup, a description of the analytic solution, and comparison of the Sierra / SM code results to the analytic solution is provided. Mesh convergence is also checked on a nightly basis for several of these tests. This documentmore » can be used to confirm that a given code capability is verified or referenced as a compilation of example problems. Additional example problems are provided in the Sierra / SM Example Problems Manual. Note, many other verification tests exist in the Sierra / SM test suite, but have not yet been included in this manual.« less

Retrospective Comparison of Cardiac Testing and Results on Inpatients with Low Pretest Probability Compared with Moderate/High Pretest Probability for Coronary Artery Disease.

PubMed

Lear, Aaron; Huber, Merritt; Canada, Amy; Robertson, Jessica; Bosman, Evan; Zyzanski, Stephen

2018-01-01

To determine whether admission, and provocative stress testing of patients who have ruled out for acute coronary syndrome put patients with low-risk category for coronary artery disease (CAD) at risk for false-positive provocative stress testing and unnecessary coronary angiogram/imaging. A retrospective chart review was performed on patients between 30 and 70 years old, with no pre-existing diagnosis of CAD, admitted to observation or inpatient status chest pain or related complaints. Included patients were categorized based on Duke Clinical Score for pretest probability for CAD into either low-risk group, or moderate/high-risk group. The inpatient course was compared including whether provocative stress testing was performed; results of stress testing; whether patients underwent further coronary imaging; and what the results of the further imaging showed. 543 patients were eligible: 305 low pretest probability, and 238 moderate/high pretest probability. No difference was found in rate of stress testing relative risk (RR) = 1.01 (95% CI, 0.852 to 1.192; P = 0); rate of positive or equivocal stress tests between the 2 groups: RR = 0.653 (95% CI, 0.415 to 1.028; P = .07,). Low-pretest-probability patients had a lower likelihood of positive coronary imaging after stress test, RR = 0.061 (95% CI, 0.004 to 0.957; P = .001). Follow-up provocative testing of all patients admitted/observed after emergency department presentation with chest pain is unlikely to find CAD in patients with low pretest probability. Testing all low-probability patients puts them at increased risk for unnecessary invasive confirmatory testing. Further prospective testing is needed to confirm these retrospective results. © Copyright 2018 by the American Board of Family Medicine.

Fuel alcohol production from agricultural lignocellulosic feedstocks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farina, G.E.; Barrier, J.W.; Forsythe, M.L.

1988-01-01

A two-stage, low-temperature, ambient pressure, acid hydrolysis process that utilizes separate unit operations to convert hemicellulose and cellulose in agricultural residues and crops to fermentable sugars is being developed and tested. Based on the results of the bench-scale tests, an acid hydrolysis experimental plant to demonstrate the concepts of low-temperature acid hydrolysis on a much larger scale was built. Plant tests using corn stover have been conducted for more that a year and conversion efficiences have equaled those achieved in the laboratory. Laboratory tests to determine the potential for low-temperature acid hydrolysis of other feedstocks - including red clover, alfalfa,more » kobe lespedeza, winter rape, and rye grass - are being conducted. Where applicable, process modifications to include extraction before or after hydrolysis also are being studied. This paper describes the experimental plant and process, results obtained in the plant, results of alternative feedstocks testing in the laboratory, and a plan for an integrated system that will produce other fuels, feed, and food from crops grown on marginal land.« less

Validation of NHB 8060.1C, Test 18 Arc Tracking, September 30, 1991

NASA Technical Reports Server (NTRS)

Linley, Larry

2005-01-01

A test project was conducted to validate Test 18 of NASA Handbook (NHB) 8060.1C and, if necessary, identify and recommend improvements in the procedures or criteria of the test. The NHB 8060.1C, Test 18 test system was modified to produce better discrimination of test results. Changes, and their effects on test results, in the graphite immersion-depth, test timing sequence, and atmospheric conditions were investigated for the wire-insulation constructions tested. Based on the test results, the graphite immersion-depths (between 0.8 mm and 1.6 mm), the timing sequence, and the change in the test conditions from ambient to three environments common in manned spaceflight did not significantly affect test results. The criteria used in Test 18 of NHB 8060.1C was found to be appropriate for qualifying arc-tracking and arc-propagation characteristics of wire-insulation materials, Using the Test 18 criteria, Kapton and ETFE were considered inappropriate for use, while PTFE was considered appropriate. Recommendations from this test project for Test 18 of NHB 8060.1C include changing the experimental setup and configurational tests and performing qualification testing in air rather than in the three environments common in manned spaceflight.

Rapid diagnostic tests for typhoid and paratyphoid (enteric) fever

PubMed Central

Wijedoru, Lalith; Mallett, Sue; Parry, Christopher M

2017-01-01

Background Differentiating both typhoid (Salmonella Typhi) and paratyphoid (Salmonella Paratyphi A) infection from other causes of fever in endemic areas is a diagnostic challenge. Although commercial point-of-care rapid diagnostic tests (RDTs) for enteric fever are available as alternatives to the current reference standard test of blood or bone marrow culture, or to the widely used Widal Test, their diagnostic accuracy is unclear. If accurate, they could potentially replace blood culture as the World Health Organization (WHO)-recommended main diagnostic test for enteric fever. Objectives To assess the diagnostic accuracy of commercially available rapid diagnostic tests (RDTs) and prototypes for detecting Salmonella Typhi or Paratyphi A infection in symptomatic persons living in endemic areas. Search methods We searched the Cochrane Infectious Diseases Group Specialized Register, MEDLINE, Embase, Science Citation Index, IndMED, African Index Medicus, LILACS, ClinicalTrials.gov, and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) up to 4 March 2016. We manually searched WHO reports, and papers from international conferences on Salmonella infections. We also contacted test manufacturers to identify studies. Selection criteria We included diagnostic accuracy studies of enteric fever RDTs in patients with fever or with symptoms suggestive of enteric fever living in endemic areas. We classified the reference standard used as either Grade 1 (result from a blood culture and a bone marrow culture) or Grade 2 (result from blood culture and blood polymerase chain reaction, or from blood culture alone). Data collection and analysis Two review authors independently extracted the test result data. We used a modified QUADAS-2 extraction form to assess methodological quality. We performed a meta-analysis when there were sufficient studies for the test and heterogeneity was reasonable. Main results Thirty-seven studies met the inclusion criteria and included a total of 5080 participants (range 50 to 1732). Enteric fever prevalence rates in the study populations ranged from 1% to 75% (median prevalence 24%, interquartile range (IQR) 11% to 46%). The included studies evaluated 16 different RDTs, and 16 studies compared two or more different RDTs. Only three studies used the Grade 1 reference standard, and only 11 studies recruited unselected febrile patients. Most included studies were from Asia, with five studies from sub-Saharan Africa. All of the RDTs were designed to detect S.Typhi infection only. Most studies evaluated three RDTs and their variants: TUBEX in 14 studies; Typhidot (Typhidot, Typhidot-M, and TyphiRapid-Tr02) in 22 studies; and the Test-It Typhoid immunochromatographic lateral flow assay, and its earlier prototypes (dipstick, latex agglutination) developed by the Royal Tropical Institute, Amsterdam (KIT) in nine studies. Meta-analyses showed an average sensitivity of 78% (95% confidence interval (CI) 71% to 85%) and specificity of 87% (95% CI 82% to 91%) for TUBEX; and an average sensitivity of 69% (95% CI 59% to 78%) and specificity of 90% (95% CI 78% to 93%) for all Test-It Typhoid and prototype tests (KIT). Across all forms of the Typhidot test, the average sensitivity was 84% (95% CI 73% to 91%) and specificity was 79% (95% CI 70% to 87%). When we based the analysis on the 13 studies of the Typhidot test that either reported indeterminate test results or where the test format means there are no indeterminate results, the average sensitivity was 78% (95% CI 65% to 87%) and specificity was 77% (95% CI 66% to 86%). We did not identify any difference in either sensitivity or specificity between TUBEX, Typhidot, and Test-it Typhoid tests when based on comparison to the 13 Typhidot studies where indeterminate results are either reported or not applicable. If TUBEX and Test-it Typhoid are compared to all Typhidot studies, the sensitivity of Typhidot was higher than Test-it Typhoid (15% (95% CI 2% to 28%), but other comparisons did not show a difference at the 95% level of CIs. In a hypothetical cohort of 1000 patients presenting with fever where 30% (300 patients) have enteric fever, on average Typhidot tests reporting indeterminate results or where tests do not produce indeterminate results will miss the diagnosis in 66 patients with enteric fever, TUBEX will miss 66, and Test-It Typhoid and prototype (KIT) tests will miss 93. In the 700 people without enteric fever, the number of people incorrectly diagnosed with enteric fever would be 161 with Typhidot tests, 91 with TUBEX, and 70 with Test-It Typhoid and prototype (KIT) tests. The CIs around these estimates were wide, with no difference in false positive results shown between tests. The quality of the data for each study was evaluated using a standardized checklist called QUADAS-2. Overall, the certainty of the evidence in the studies that evaluated enteric fever RDTs was low. Authors' conclusions In 37 studies that evaluated the diagnostic accuracy of RDTs for enteric fever, few studies were at a low risk of bias. The three main RDT tests and variants had moderate diagnostic accuracy. There was no evidence of a difference between the average sensitivity and specificity of the three main RDT tests. More robust evaluations of alternative RDTs for enteric fever are needed. The accuracy of rapid diagnostic tests for detecting typhoid and paratyphoid (enteric) fever Cochrane researchers assessed the accuracy of commercially-available rapid diagnostic tests and their prototypes (including TUBEX, Typhidot, Typhidot-M, Test-it Typhoid, and other tests) for detecting typhoid and paratyphoid (enteric) fever in people living in countries where the estimated number of individuals with the disease at any one time is greater than 10 per 100,000 population. If accurate, they could replace the current World Health Organization (WHO)-recommended diagnostic test: culture (growing the bacteria that causes the infection from a patient’s blood or bone marrow). Background Typhoid fever and paratyphoid fever are infections caused by the bacteria Salmonella Typhi and Salmonella Paratyphi A respectively. The term ‘enteric fever’ is used to describe both infections. Enteric fever can be difficult to diagnose as the signs and symptoms are similar to those of other infectious diseases that cause fever such as malaria. The recommended test to confirm if a person has enteric fever is to grow the Salmonella from their blood. It takes at least 48 hours to give a result, so cannot help healthcare workers make a diagnosis the same day the blood culture is taken. Blood cultures may give a negative result even though a person has enteric fever. The test also requires a laboratory and trained staff, which are often unavailable in communities where enteric fever is common. Rapid diagnostic tests (RDTs) are designed to be easy to use, and to deliver a quick result without the need for a blood culture laboratory. The cost of an enteric fever RDT would be significantly less than a blood culture, and requires less training to perform. Study characteristics Cochrane researchers searched the available literature up to 4 March 2016 and included 37 studies. Most studies recruited participants from South Asia. Most participants were adults, with 22 studies including children. All of the RDTs evaluated detected Salmonella Typhi (typhoid fever) only. Quality of the evidence The Cochrane researchers evaluated the quality of the data for each study using a standardized checklist called QUADAS-2. High quality studies that compared different types of RDT in the same patients were few in number. Two-thirds of the included studies did not evaluate the RDTs in the context of patients who are typically tested for the disease. Many studies utilized a particular study design (a case control study) which risks overestimating RDT accuracy. In the studies evaluating the Typhidot RDT, it was often unclear how many test results were indeterminate, when the test cannot distinguish a current episode of infection from a previous disease episode. Overall, the certainty of the evidence in the studies that evaluated enteric fever RDTs was low. Key results Sensitivity indicates the percentage of patients with a positive test result who are correctly diagnosed with disease. Specificity indicates the percentage of patients who are correctly identified as not having disease. TUBEX showed an average sensitivity of 78% and specificity of 87%. Typhidot studies, grouped together to include Typhidot, Typhidot-M, and TyphiRapid-Tr02, showed an average sensitivity of 84% and specificity of 79%. When Typhidot studies with clear reporting of indeterminate results are considered, the average sensitivity and specificity of Typhidot was 78% and 77% respectively. Test-It Typhoid and prototypes (KIT) showed an average sensitivity of 69% and specificity of 90%. Based on these results, in 1000 patients with fever where 30% (300 patients) have enteric fever, we would expect Typhidot tests reporting indeterminate results or where tests do not produce indeterminate results to, on average, miss the diagnosis (give a false negative result) in 66 patients with enteric fever, TUBEX to miss 66, and Test-It Typhoid and prototypes (KIT) to miss 93. In the 700 people without enteric fever, the number of people incorrectly given a diagnosis of enteric fever (a false positive result) would be on average 161 with these Typhidot tests, 91 with TUBEX, and 70 with the Test-It Typhoid and prototypes (KIT). These differences in the number of false negative and false positive results in patients from the different tests are not statistically important. The RDTs evaluated are not sufficiently accurate to replace blood culture as a diagnostic test for enteric fever. PMID:28545155

Pressure vessel burst test program - Initial program paper

NASA Technical Reports Server (NTRS)

Cain, Maurice R.; Sharp, Douglas E.; Coleman, Michael D.; Webb, Bobby L.

1990-01-01

The current status of a pressure vessel burst test program, aimed at the study of the blast waves and fragmentation characteristics of ruptured gas-filled pressure vessels, is reported. The program includes a series of test plans, each involving multiple bursts with burst pressures ranging to 7500 psig. The discussion covers the identification of concerns and hazards, application of the data generated, and a brief review of the current methods for assessing vessel safety and burst parameters. Attention is also given to pretest activities, including completed vessel and facility/instrumentation preparation and results of completed preliminary burst tests.

Diagnostic Testing and Interpretation of Tests for Autoimmunity

PubMed Central

Castro, Christine; Gourley, Mark

2010-01-01

Laboratory testing is of great value when evaluating a patient with a suspected autoimmune disease. The results can confirm a diagnosis, estimate disease severity, aid in assessing prognosis and are useful to follow disease activity. Components of the laboratory exam include complete blood count with differential, comprehensive metabolic panel, inflammatory markers, autoantibodies, and flow cytometry. This chapter discusses these components and includes a discussion about organ-specific immunologic diseases where immunological laboratory testing is employed. Comprehensive laboratory evaluation of a suspected autoimmune illness in conjunction with a thorough clinical evaluation provides a better understanding of a patient's immunologic disease. PMID:20061009

Safety Performance of Small Lithium-Ion Cells in High Voltage Batteries

NASA Technical Reports Server (NTRS)

Cowles, Philip R.; Darcy, Eric C.; Davies, Frank J.; Jeevarajan, Judith A.; Spurrett, Robert P.

2003-01-01

Topics covered include: Small-cell EAPU work done by NASA-JSC & COM DEV; Looking at safety features (short circuit protection - PTCs); Early tests showed that long strings do not withstand short circuit; a) Some PTCs experience large negative voltages; b) Destructive results. Solution: group cells into shorter substrings, with bypass diodes Work included: a) Tests with single cells shorted; b) Tests with single cells with imposed-negative voltages; c) 6s, 7s and 8s string shorts; and d) Tests with protection scheme in place, on 12s and 41s x 5p.

Frequency-Domain Identification Of Aeroelastic Modes

NASA Technical Reports Server (NTRS)

Acree, C. W., Jr.; Tischler, Mark B.

1991-01-01

Report describes flight measurements and frequency-domain analyses of aeroelastic vibrational modes of wings of XV-15 tilt-rotor aircraft. Begins with description of flight-test methods. Followed by brief discussion of methods of analysis, which include Fourier-transform computations using chirp z transformers, use of coherence and other spectral functions, and methods and computer programs to obtain frequencies and damping coefficients from measurements. Includes brief description of results of flight tests and comparisions among various experimental and theoretical results. Ends with section on conclusions and recommended improvements in techniques.

The relevance of external quality assessment for molecular testing for ALK positive non-small cell lung cancer: results from two pilot rounds show room for optimization.

PubMed

Tembuyser, Lien; Tack, Véronique; Zwaenepoel, Karen; Pauwels, Patrick; Miller, Keith; Bubendorf, Lukas; Kerr, Keith; Schuuring, Ed; Thunnissen, Erik; Dequeker, Elisabeth M C

2014-01-01

Molecular profiling should be performed on all advanced non-small cell lung cancer with non-squamous histology to allow treatment selection. Currently, this should include EGFR mutation testing and testing for ALK rearrangements. ROS1 is another emerging target. ALK rearrangement status is a critical biomarker to predict response to tyrosine kinase inhibitors such as crizotinib. To promote high quality testing in non-small cell lung cancer, the European Society of Pathology has introduced an external quality assessment scheme. This article summarizes the results of the first two pilot rounds organized in 2012-2013. Tissue microarray slides consisting of cell-lines and resection specimens were distributed with the request for routine ALK testing using IHC or FISH. Participation in ALK FISH testing included the interpretation of four digital FISH images. Data from 173 different laboratories was obtained. Results demonstrate decreased error rates in the second round for both ALK FISH and ALK IHC, although the error rates were still high and the need for external quality assessment in laboratories performing ALK testing is evident. Error rates obtained by FISH were lower than by IHC. The lowest error rates were observed for the interpretation of digital FISH images. There was a large variety in FISH enumeration practices. Based on the results from this study, recommendations for the methodology, analysis, interpretation and result reporting were issued. External quality assessment is a crucial element to improve the quality of molecular testing.

Development of an accelerated reliability test schedule for terrestrial solar cells

NASA Technical Reports Server (NTRS)

Lathrop, J. W.; Prince, J. L.

1981-01-01

An accelerated test schedule using a minimum amount of tests and a minimum number of cells has been developed on the basis of stress test results obtained from more than 1500 cells of seven different cell types. The proposed tests, which include bias-temperature, bias-temperature-humidity, power cycle, thermal cycle, and thermal shock tests, use as little as 10 and up to 25 cells, depending on the test type.

Inflammatory disorders mimicking periprosthetic joint infections may result in false positive α-defensin.

PubMed

Plate, Andreas; Stadler, Laura; Sutter, Reto; Anagnostopoulos, Alexia; Frustaci, Dario; Zbinden, Reinhard; Fucentese, Sandro F; Zinkernagel, Annelies S; Zingg, Patrick O; Achermann, Yvonne

2018-02-26

The antimicrobial peptide α-defensin has recently been introduced as potential "single" biomarker with a high sensitivity and specificity for the preoperative diagnosis of periprosthetic joint infections (PJIs). However, most studies assessed the benefits of the test with exclusion of patients with rheumatic diseases. We aimed to evaluate the α-defensin test in a cohort study without exclusion of cases with inflammatory diseases. Between June 2016 and June 2017, we prospectively included cases with a suspected PJI and an available lateral flow test α-defensin (Synovasure®) in synovial fluid. We compared the test result to the diagnostic criteria for PJIs published by an International Consensus Group in 2013. We included 109 cases (49 hips, 60 knees) in which preoperative α-defensin tests had been performed. Thereof, 20 PJIs (16 hips, 4 knees) were diagnosed. Preoperative α-defensin tests were positive in 25 cases (22.9%) with a test sensitivity and specificity of 90% and 92.1% (95% confidence interval [CI], 68.3 - 98.8% and 84.5 - 96.8%, respectively), and a high negative predictive value of 97.6% (95% CI, 91.7 - 99.4%). We interpreted seven α-defensin tests as false positive, mainly in cases with inflammatory rheumatic diseases, including crystal deposition diseases. A negative synovial α-defensin test can reliably rule out a PJI. However, the test can be false positive in conjunction with an underlying non-infectious inflammatory disease. We therefore propose to use the α-defensin test only in addition to MSIS criteria and assessment for crystals in synovial aspirates. Copyright © 2018. Published by Elsevier Ltd.

Test and Measurement Expert Opinions: A Dialogue about Testing Students with Disabilities Out of Level in Large-Scale Assessments. Out-of-Level Testing Report.

ERIC Educational Resources Information Center

Minnema, Jane; Thurlow, Martha; Bielinski, John

Two focus groups of test and measurement experts were held to explore the use of out-of-level testing for students with disabilities. The participants (n=17) included state and federal level assessment personnel, test company employees, and university professors. A content analysis of the narrative results indicated that there was no clear…

Design certification tests: High Pressure Oxygen Filter (HPOF) program. Summary report

NASA Technical Reports Server (NTRS)

Smith, I. D.

1976-01-01

Design and acceptance certification test procedures and results are presented for a high pressure oxygen filter developed to protect the sealing surfaces in emergency oxygen systems. Equipment specifications are included.

Graphics Processor Units (GPUs)

NASA Technical Reports Server (NTRS)

Wyrwas, Edward J.

2017-01-01

This presentation will include information about Graphics Processor Units (GPUs) technology, NASA Electronic Parts and Packaging (NEPP) tasks, The test setup, test parameter considerations, lessons learned, collaborations, a roadmap, NEPP partners, results to date, and future plans.

Final test report for ITS standards testing of ATC 2070 and its cabinet as deployed in Harris County, TX.

DOT National Transportation Integrated Search

2008-06-27

This Final Report includes all of the findings and recommendations resulting from Battelles static review, detailed interviews and onsite testing activity related to the ITS Standards deployed and currently in use for transportation management sys...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Warpinski, N.R.; Branagan, P.T.; Sattler, A.R.

This paper is a case study of the stimulation and testing of tight, lenticular sands in the paludal interval of the Mesaverde group in the Piceance basin at DOE's Multiwell Experiment (MWX) site in Colorado. Topics discussed include geologic data, stress test results, well testing, laboratory core studies, stimulation and stimulation analyses, and postfracture operations.

241-AZ-101 Waste Tank Color Video Camera System Shop Acceptance Test Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

WERRY, S.M.

2000-03-23

This report includes shop acceptance test results. The test was performed prior to installation at tank AZ-101. Both the camera system and camera purge system were originally sought and procured as a part of initial waste retrieval project W-151.

46 CFR 178.215 - Weight of passengers and crew.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., for which stability information is based on the results of a simplified stability proof test. (b... simplified stability proof test and the number of passengers and crew included in the total test weight... TONS) INTACT STABILITY AND SEAWORTHINESS Stability Instructions for Operating Personnel § 178.215...

46 CFR 178.215 - Weight of passengers and crew.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., for which stability information is based on the results of a simplified stability proof test. (b... simplified stability proof test and the number of passengers and crew included in the total test weight... TONS) INTACT STABILITY AND SEAWORTHINESS Stability Instructions for Operating Personnel § 178.215...

46 CFR 178.215 - Weight of passengers and crew.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., for which stability information is based on the results of a simplified stability proof test. (b... simplified stability proof test and the number of passengers and crew included in the total test weight... TONS) INTACT STABILITY AND SEAWORTHINESS Stability Instructions for Operating Personnel § 178.215...

46 CFR 178.215 - Weight of passengers and crew.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., for which stability information is based on the results of a simplified stability proof test. (b... simplified stability proof test and the number of passengers and crew included in the total test weight... TONS) INTACT STABILITY AND SEAWORTHINESS Stability Instructions for Operating Personnel § 178.215...

Audit of Trichomonas vaginalis test requesting by community referrers after a change from culture to molecular testing, including a cost analysis.

PubMed

Bissessor, Liselle; Wilson, Janet; McAuliffe, Gary; Upton, Arlo

2017-06-16

Trichomonas vaginalis (TV) prevalence varies among different communities and peoples. The availability of robust molecular platforms for the detection of TV has advanced diagnosis; however, molecular tests are more costly than phenotypic methodologies, and testing all urogenital samples is costly. We recently replaced culture methods with the Aptima Trichomonas vaginalis nucleic acid amplification test on specific request and as reflex testing by the laboratory, and have audited this change. Data were collected from August 2015 (microbroth culture and microscopy) and August 2016 (Aptima TV assay) including referrer, testing volumes, results and test cost estimates. In August 2015, 10,299 vaginal swabs, and in August 2016, 2,189 specimens (urogenital swabs and urines), were tested. The positivity rate went from 0.9% to 5.3%, and overall more TV infections were detected in 2016. The number needed to test and cost for one positive TV result respectively was 111 and $902.55 in 2015, and 19 and $368.92 in 2016. Request volumes and positivity rates differed among referrers. The methodology change was associated with higher overall detection of TV, and reductions in the numbers needed to test/cost for one TV diagnosis. Our audit suggests that there is room for improvement with TV test requesting in our community.

Experience in Grid Site Testing for ATLAS, CMS and LHCb with HammerCloud

NASA Astrophysics Data System (ADS)

Elmsheuser, Johannes; Medrano Llamas, Ramón; Legger, Federica; Sciabà, Andrea; Sciacca, Gianfranco; Úbeda García, Mario; van der Ster, Daniel

2012-12-01

Frequent validation and stress testing of the network, storage and CPU resources of a grid site is essential to achieve high performance and reliability. HammerCloud was previously introduced with the goals of enabling VO- and site-administrators to run such tests in an automated or on-demand manner. The ATLAS, CMS and LHCb experiments have all developed VO plugins for the service and have successfully integrated it into their grid operations infrastructures. This work will present the experience in running HammerCloud at full scale for more than 3 years and present solutions to the scalability issues faced by the service. First, we will show the particular challenges faced when integrating with CMS and LHCb offline computing, including customized dashboards to show site validation reports for the VOs and a new API to tightly integrate with the LHCbDIRAC Resource Status System. Next, a study of the automatic site exclusion component used by ATLAS will be presented along with results for tuning the exclusion policies. A study of the historical test results for ATLAS, CMS and LHCb will be presented, including comparisons between the experiments’ grid availabilities and a search for site-based or temporal failure correlations. Finally, we will look to future plans that will allow users to gain new insights into the test results; these include developments to allow increased testing concurrency, increased scale in the number of metrics recorded per test job (up to hundreds), and increased scale in the historical job information (up to many millions of jobs per VO).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

In this quarterly technical progress report, UTSI reports on progress on a multitask contract to develop the necessary technology for the steam bottoming plant of the MHD Steam Combined Cycle power plant. A Proof-Of-Concept (POC) test was conducted during the quarter and the results are reported. This POC test was terminated after 88 hours of operation due to the failure of the coal pulverizer main shaft. Preparations for the test and post-test activities are summarized. Modifications made to the dry electrostatic precipitator (ESP) are described and measurements of its performance are reported. The baghouse performance is summarized, together with actionsmore » being taken to improve bag cleaning using reverse air. Data on the wet ESP performance is included at two operating conditions, including verification that it met State of Tennessee permit conditions for opacity with all the flow through it. The results of experiments to determine the effect of potassium seed on NO{sub x} emissions and secondary combustion are reported. The status of efforts to quantify the detailed mass balance for all POC testing is summarized. The work to develop a predictive ash deposition model is discussed and results compared with deposition actually encountered during the test. Plans to measure the kinetics of potassium and sulfur on flames like the secondary combustor, are included. Advanced diagnostic work by both UTSI and MSU is reported. Efforts to develop the technology for a high temperature air heater using ceramic tubes are summarized.« less

Testing the Grossman model of medical spending determinants with macroeconomic panel data.

PubMed

Hartwig, Jochen; Sturm, Jan-Egbert

2018-02-16

Michael Grossman's human capital model of the demand for health has been argued to be one of the major achievements in theoretical health economics. Attempts to test this model empirically have been sparse, however, and with mixed results. These attempts so far relied on using-mostly cross-sectional-micro data from household surveys. For the first time in the literature, we bring in macroeconomic panel data for 29 OECD countries over the period 1970-2010 to test the model. To check the robustness of the results for the determinants of medical spending identified by the model, we include additional covariates in an extreme bounds analysis (EBA) framework. The preferred model specifications (including the robust covariates) do not lend much empirical support to the Grossman model. This is in line with the mixed results of earlier studies.

Efficient concepts for large erectable space structures

NASA Technical Reports Server (NTRS)

Card, M. F.; Bush, H. G.; Heard, W. L., Jr.; Mikulas, M. M., Jr.

1978-01-01

The status of Langley Research Center development of the nestable column concept is reviewed including results of member and truss component tests, and planned assembly studies. In addition, more recent studies of alternative member concepts are presented. Preliminary results on relative efficiency of several types of truss-type columns are compared and future test plans discussed.

Shear-Panel Test Fixture Eliminates Corner Stresses

NASA Technical Reports Server (NTRS)

Kiss, J. J.; Farley, G. L.; Baker, D. J.

1984-01-01

New design eliminates corner stresses while maintaining uniform stress across panel. Shear panel test fixture includes eight frames and eight corner pins. Fixture assembled in two halves with shear panel sandwiched in between. Results generated from this fixture will result in good data base for design of efficient aircraft structures and other applications.

Emissions of PCDD/Fs, PCBs, and PAHs from a modern diesel engine equipped with catalyzed emission control systems.

PubMed

Laroo, Christopher A; Schenk, Charles R; Sanchez, L James; McDonald, Joseph

2011-08-01

Exhaust emissions of 17 2,3,7,8-substituted chlorinated dibenzo-p-dioxin/furan (CDD/F) congeners, tetra-octa CDD/F homologues, 12 2005 WHO chlorinated biphenyls (CB) congeners, mono-nona CB homologues, and 19 polycyclic aromatic hydrocarbons (PAHs) from a model year 2008 Cummins ISB engine were investigated. Testing included configurations composed of different combinations of aftertreatment including a diesel oxidation catalyst (DOC), catalyzed diesel particulate filter (CDPF), copper zeolite urea selective catalytic reduction (SCR), iron zeolite SCR, and ammonia slip catalyst. Results were compared to a baseline engine out configuration. Testing included the use of fuel that contained the maximum expected chlorine (Cl) concentration of U.S. highway diesel fuel and a Cl level 1.5 orders of magnitude above. Results indicate there is no risk for an increase in polychlorinated dibenzo-p-dioxin/furan and polychlorinated biphenyl emissions from modern diesel engines with catalyzed aftertreatment when compared to engine out emissions for configurations tested in this program. These results, along with PAH results, compare well with similar results from modern diesel engines in the literature. The results further indicate that polychlorinated dibenzo-p-dioxin/furan emissions from modern diesel engines both with and without aftertreatment are below historical values reported in the literature as well as the current inventory value.

Expert Knowledge Influences Decision-Making for Couples Receiving Positive Prenatal Chromosomal Microarray Testing Results.

PubMed

Rubel, M A; Werner-Lin, A; Barg, F K; Bernhardt, B A

2017-09-01

To assess how participants receiving abnormal prenatal genetic testing results seek information and understand the implications of results, 27 US female patients and 12 of their male partners receiving positive prenatal microarray testing results completed semi-structured phone interviews. These interviews documented participant experiences with chromosomal microarray testing, understanding of and emotional response to receiving results, factors affecting decision-making about testing and pregnancy termination, and psychosocial needs throughout the testing process. Interview data were analyzed using a modified grounded theory approach. In the absence of certainty about the implications of results, understanding of results is shaped by biomedical expert knowledge (BEK) and cultural expert knowledge (CEK). When there is a dearth of BEK, as in the case of receiving results of uncertain significance, participants rely on CEK, including religious/spiritual beliefs, "gut instinct," embodied knowledge, and social network informants. CEK is a powerful platform to guide understanding of prenatal genetic testing results. The utility of culturally situated expert knowledge during testing uncertainty emphasizes that decision-making occurs within discourses beyond the biomedical domain. These forms of "knowing" may be integrated into clinical consideration of efficacious patient assessment and counseling.

High Stakes Testing and Teacher Access to Professional Opportunities: Lessons from Indonesia

ERIC Educational Resources Information Center

Ashadi, Ashadi; Rice, Suzanne

2016-01-01

High-stakes testing regimes, in which schools are judged on their capacity to attain high student results in national tests, are becoming common in both developed and developing nations, including the United States, Britain and Australia. However, while there has been substantial investigation around the impact of high-stakes testing on curriculum…

Development of a Cavitation Erosion Resistant Advanced Material System

DTIC Science & Technology

2005-11-01

Sheet EPD M results .............................................................................. 47 Figure 5.11 - EPDM rubber samples, sheet (left...Testing The long test times of EPDM rubber and other durable elastomer samples created a need for overnight testing capability. In the original test setup...seals, adhesives and molded flexible parts. Common examples of elastomers include natural and synthetic rubber , silicone, neoprene, EPDM , polyurethane

The CF6 jet engine performance improvement: New front mount

NASA Technical Reports Server (NTRS)

Fasching, W. A.

1979-01-01

The New Front Mount was evaluated in component tests including stress, deflection/distortion and fatigue tests. The test results demonstrated a performance improvement of 0.1% in cruise sfc, 16% in compressor stall margin and 10% in compressor stator angle margin. The New Front Mount hardware successfully completed 35,000 simulated flight cycles endurance testing.

An antenna pointing mechanism for large reflector antennas

NASA Technical Reports Server (NTRS)

Heimerdinger, H.

1981-01-01

An antenna pointing mechanism for large reflector antennas on direct broadcasting communication satellites was built and tested. After listing the requirements and constraints for this equipment the model is described, and performance figures are given. Futhermore, results of the qualification level tests, including functional, vibrational, thermovacuum, and accelerated life tests are reported. These tests were completed successfully.

Construction and Evaluation of Reliability and Validity of Reasoning Ability Test

ERIC Educational Resources Information Center

Bhat, Mehraj A.

2014-01-01

This paper is based on the construction and evaluation of reliability and validity of reasoning ability test at secondary school students. In this paper an attempt was made to evaluate validity, reliability and to determine the appropriate standards to interpret the results of reasoning ability test. The test includes 45 items to measure six types…

Clinical history as a predictor of penicillin skin test outcome.

PubMed

Wong, Benjamin B L; Keith, Paul K; Waserman, Susan

2006-08-01

Up to 10% of the population reports an "allergy" to penicillin, whereas approximately 1.1% has positive penicillin skin test results. Where penicillin skin tests are unavailable, some have advocated using history to decide whether to use a penicillin-related antibiotic. To determine if clinical history predicts penicillin skin test results. Retrospective medical record review of 94 consecutive patients who had previously taken penicillin referred for penicillin allergy. Case histories were taken, penicillin skin tests performed, and an oral challenge recommended if skin test results were negative. Of 91 cases studied, the average patient age was 27 years (range, 6 months to 82 years; 36% female). Fifty-two (57%) experienced hives as their main adverse reaction. Sixteen (18%) had at least 1 positive test result. Of this group, 9 had hives as their main symptom, whereas 1 had respiratory problems and 1 had angioedema. Most patients with positive skin test results had experienced their reaction at least 3 years ago. Regression analysis showed that age, sex, and clinical history, including type of reaction, time of reaction after penicillin ingestion, or time since the last reaction, were not associated with skin test positivity. Seventy-two (96%) of the 75 patients who had negative skin test results underwent oral challenge. Seventy had negative challenge results. The negative predictive value of a negative penicillin skin test result was 97%. Clinical history was not predictive of subsequent penicillin skin test results.

Health effects from fallout.

PubMed

Gilbert, Ethel S; Land, Charles E; Simon, Steven L

2002-05-01

This paper primarily discusses health effects that have resulted from exposures received as a result of above-ground nuclear tests, with emphasis on thyroid disease from exposure to 131I and leukemia and solid cancers from low dose rate external and internal exposure. Results of epidemiological studies of fallout exposures in the Marshall Islands and from the Nevada Test Site are summarized, and studies of persons with exposures similar to those from fallout are briefly reviewed (including patients exposed to 131I for medical reasons and workers exposed externally at low doses and low dose rates). Promising new studies of populations exposed in countries of the former Soviet Union are also discussed and include persons living near the Semipalatinsk Test Site in Kazakhstan, persons exposed as a result of the Chernobyl accident, and persons exposed as a result of operations of the Mayak Nuclear Plant in the Russian Federation. Very preliminary estimates of cancer risks from fallout doses received by the United States population are presented.

TALARIS project update: Overview of flight testing and development of a prototype planetary surface exploration hopper

NASA Astrophysics Data System (ADS)

Rossi, Christopher; Cunio, Phillip M.; Alibay, Farah; Morrow, Joe; Nothnagel, Sarah L.; Steiner, Ted; Han, Christopher J.; Lanford, Ephraim; Hoffman, Jeffrey A.

2012-12-01

The TALARIS (Terrestrial Artificial Lunar And Reduced GravIty Simulator) project is intended to test GNC (Guidance, Navigation, and Control) algorithms on a prototype planetary surface exploration hopper in a dynamic environment with simulated reduced gravity. The vehicle is being developed by the Charles Stark Draper Laboratory and Massachusetts Institute of Technology in support of efforts in the Google Lunar X-Prize contest. This paper presents progress achieved since September 2010 in vehicle development and flight testing. Upgrades to the vehicle are described, including a redesign of the power train for the gravity-offset propulsion system and a redesign of key elements of the spacecraft emulator propulsion system. The integration of flight algorithms into modular flight software is also discussed. Results are reported for restricted degree of freedom (DOF) tests used to tune GNC algorithms on the path to a full 6-DOF hover-hop flight profile. These tests include 3-DOF tests on flat surfaces restricted to horizontal motion, and 2-DOF vertical tests restricted to vertical motion and 1-DOF attitude control. The results of tests leading up to full flight operations are described, as are lessons learned and future test plans.

SU-F-T-249: Application of Human Factors Methods: Usability Testing in the Radiation Oncology Environment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Warkentin, H; Bubric, K; Giovannetti, H

2016-06-15

Purpose: As a quality improvement measure, we undertook this work to incorporate usability testing into the implementation procedures for new electronic documents and forms used by four affiliated radiation therapy centers. Methods: A human factors specialist provided training in usability testing for a team of medical physicists, radiation therapists, and radiation oncologists from four radiotherapy centers. A usability testing plan was then developed that included controlled scenarios and standardized forms for qualitative and quantitative feedback from participants, including patients. Usability tests were performed by end users using the same hardware and viewing conditions that are found in the clinical environment.more » A pilot test of a form used during radiotherapy CT simulation was performed in a single department; feedback informed adaptive improvements to the electronic form, hardware requirements, resource accessibility and the usability testing plan. Following refinements to the testing plan, usability testing was performed at three affiliated cancer centers with different vault layouts and hardware. Results: Feedback from the testing resulted in the detection of 6 critical errors (omissions and inability to complete task without assistance), 6 non-critical errors (recoverable), and multiple suggestions for improvement. Usability problems with room layout were detected at one center and problems with hardware were detected at one center. Upon amalgamation and summary of the results, three key recommendations were presented to the document’s authors for incorporation into the electronic form. Documented inefficiencies and patient safety concerns related to the room layout and hardware were presented to administration along with a request for funding to purchase upgraded hardware and accessories to allow a more efficient workflow within the simulator vault. Conclusion: By including usability testing as part of the process when introducing any new document or procedure into clinical use, associated risks can be identified and mitigated before patient care and clinical workflow are impacted.« less

Remote sensing and field test capabilities at U.S. Army Dugway Proving Ground

NASA Astrophysics Data System (ADS)

Pearson, James T.; Herron, Joshua P.; Marshall, Martin S.

2011-11-01

U.S. Army Dugway Proving Ground (DPG) is a Major Range and Test Facility Base (MRTFB) with the mission of testing chemical and biological defense systems and materials. DPG facilities include state-of-the-art laboratories, extensive test grids, controlled environment calibration facilities, and a variety of referee instruments for required test measurements. Among these referee instruments, DPG has built up a significant remote sensing capability for both chemical and biological detection. Technologies employed for remote sensing include FTIR spectroscopy, UV spectroscopy, Raman-shifted eye-safe lidar, and other elastic backscatter lidar systems. These systems provide referee data for bio-simulants, chemical simulants, toxic industrial chemicals (TICs), and toxic industrial materials (TIMs). In order to realize a successful large scale open-air test, each type of system requires calibration and characterization. DPG has developed specific calibration facilities to meet this need. These facilities are the Joint Ambient Breeze Tunnel (JABT), and the Active Standoff Chamber (ASC). The JABT and ASC are open ended controlled environment tunnels. Each includes validation instrumentation to characterize simulants that are disseminated. Standoff systems are positioned at typical field test distances to measure characterized simulants within the tunnel. Data from different types of systems can be easily correlated using this method, making later open air test results more meaningful. DPG has a variety of large scale test grids available for field tests. After and during testing, data from the various referee instruments is provided in a visual format to more easily draw conclusions on the results. This presentation provides an overview of DPG's standoff testing facilities and capabilities, as well as example data from different test scenarios.

Remote sensing and field test capabilities at U.S. Army Dugway Proving Ground

NASA Astrophysics Data System (ADS)

Pearson, James T.; Herron, Joshua P.; Marshall, Martin S.

2012-05-01

U.S. Army Dugway Proving Ground (DPG) is a Major Range and Test Facility Base (MRTFB) with the mission of testing chemical and biological defense systems and materials. DPG facilities include state-of-the-art laboratories, extensive test grids, controlled environment calibration facilities, and a variety of referee instruments for required test measurements. Among these referee instruments, DPG has built up a significant remote sensing capability for both chemical and biological detection. Technologies employed for remote sensing include FTIR spectroscopy, UV spectroscopy, Raman-shifted eye-safe lidar, and other elastic backscatter lidar systems. These systems provide referee data for bio-simulants, chemical simulants, toxic industrial chemicals (TICs), and toxic industrial materials (TIMs). In order to realize a successful large scale open-air test, each type of system requires calibration and characterization. DPG has developed specific calibration facilities to meet this need. These facilities are the Joint Ambient Breeze Tunnel (JABT), and the Active Standoff Chamber (ASC). The JABT and ASC are open ended controlled environment tunnels. Each includes validation instrumentation to characterize simulants that are disseminated. Standoff systems are positioned at typical field test distances to measure characterized simulants within the tunnel. Data from different types of systems can be easily correlated using this method, making later open air test results more meaningful. DPG has a variety of large scale test grids available for field tests. After and during testing, data from the various referee instruments is provided in a visual format to more easily draw conclusions on the results. This presentation provides an overview of DPG's standoff testing facilities and capabilities, as well as example data from different test scenarios.

Results of Third-Grade Students in a Reform Curriculum on the Illinois State Mathematics Test.

ERIC Educational Resources Information Center

Carroll, William M.

1997-01-01

Reports on the results of the reform curriculum of the University of Chicago School Mathematics Project's elementary curriculum, Everyday Mathematics, for third-grade students. Results included the fact that only 2% of UCSMP students failed to meet state goals. UCSMP students also scored well in all mathematical areas including number skills and…

Full-scale aircraft cabin flammability tests of improved fire-resistant materials

NASA Technical Reports Server (NTRS)

Stuckey, R. N.; Surpkis, D. E.; Price, L. J.

1974-01-01

Full-scale aircraft cabin flammability tests to evaluate the effectiveness of new fire-resistant materials by comparing their burning characteristics with those of older aircraft materials are described. Three tests were conducted and are detailed. Test 1, using pre-1968 materials, was run to correlate the procedures and to compare the results with previous tests by other organizations. Test 2 included newer, improved fire-resistant materials. Test 3 was essentially a duplicate of test 2, but a smokeless fuel was used. Test objectives, methods, materials, and results are presented and discussed. Results indicate that the pre-1968 materials ignited easily, allowed the fire to spread, produced large amounts of smoke and toxic combustion products, and resulted in a flash fire and major fire damage. The newer fire-resistant materials did not allow the fire to spread. Furthermore, they produced less, lower concentrations of toxic combustion products, and lower temperatures. The newer materials did not produce a flash fire.

A Comparison Between The NORCAT Rover Test Results and the ISRU Excavation System Model Predictions Results

NASA Technical Reports Server (NTRS)

Gallo, Christopher A.; Agui, Juan H.; Creager, Colin M.; Oravec, Heather A.

2012-01-01

An Excavation System Model has been written to simulate the collection and transportation of regolith on the moon. The calculations in this model include an estimation of the forces on the digging tool as a result of excavation into the regolith. Verification testing has been performed and the forces recorded from this testing were compared to the calculated theoretical data. The Northern Centre for Advanced Technology Inc. rovers were tested at the NASA Glenn Research Center Simulated Lunar Operations facility. This testing was in support of the In-Situ Resource Utilization program Innovative Partnership Program. Testing occurred in soils developed at the Glenn Research Center which are a mixture of different types of sands and whose soil properties have been well characterized. This testing is part of an ongoing correlation of actual field test data to the blade forces calculated by the Excavation System Model. The results from this series of tests compared reasonably with the predicted values from the code.

21 CFR 3.7 - Request for designation.

Code of Federal Regulations, 2013 CFR

2013-04-01

... biological composition; (vi) Status and brief reports of the results of developmental work, including animal testing; (vii) Description of the manufacturing processes, including the sources of all components; (viii...

21 CFR 3.7 - Request for designation.

Code of Federal Regulations, 2011 CFR

2011-04-01

... biological composition; (vi) Status and brief reports of the results of developmental work, including animal testing; (vii) Description of the manufacturing processes, including the sources of all components; (viii...

21 CFR 3.7 - Request for designation.

Code of Federal Regulations, 2010 CFR

2010-04-01

... biological composition; (vi) Status and brief reports of the results of developmental work, including animal testing; (vii) Description of the manufacturing processes, including the sources of all components; (viii...

21 CFR 3.7 - Request for designation.

Code of Federal Regulations, 2014 CFR

2014-04-01

... biological composition; (vi) Status and brief reports of the results of developmental work, including animal testing; (vii) Description of the manufacturing processes, including the sources of all components; (viii...

21 CFR 3.7 - Request for designation.

Code of Federal Regulations, 2012 CFR

2012-04-01

... biological composition; (vi) Status and brief reports of the results of developmental work, including animal testing; (vii) Description of the manufacturing processes, including the sources of all components; (viii...

Economic evaluation of laboratory testing strategies for hospital-associated Clostridium difficile infection.

PubMed

Schroeder, Lee F; Robilotti, Elizabeth; Peterson, Lance R; Banaei, Niaz; Dowdy, David W

2014-02-01

Clostridium difficile infection (CDI) is the most common cause of infectious diarrhea in health care settings, and for patients presumed to have CDI, their isolation while awaiting laboratory results is costly. Newer rapid tests for CDI may reduce this burden, but the economic consequences of different testing algorithms remain unexplored. We used decision analysis from the hospital perspective to compare multiple CDI testing algorithms for adult inpatients with suspected CDI, assuming patient management according to laboratory results. CDI testing strategies included combinations of on-demand PCR (odPCR), batch PCR, lateral-flow diagnostics, plate-reader enzyme immunoassay, and direct tissue culture cytotoxicity. In the reference scenario, algorithms incorporating rapid testing were cost-effective relative to nonrapid algorithms. For every 10,000 symptomatic adults, relative to a strategy of treating nobody, lateral-flow glutamate dehydrogenase (GDH)/odPCR generated 831 true-positive results and cost $1,600 per additional true-positive case treated. Stand-alone odPCR was more effective and more expensive, identifying 174 additional true-positive cases at $6,900 per additional case treated. All other testing strategies were dominated by (i.e., more costly and less effective than) stand-alone odPCR or odPCR preceded by lateral-flow screening. A cost-benefit analysis (including estimated costs of missed cases) favored stand-alone odPCR in most settings but favored odPCR preceded by lateral-flow testing if a missed CDI case resulted in less than $5,000 of extended hospital stay costs and <2 transmissions, if lateral-flow GDH diagnostic sensitivity was >93%, or if the symptomatic carrier proportion among the toxigenic culture-positive cases was >80%. These results can aid guideline developers and laboratory directors who are considering rapid testing algorithms for diagnosing CDI.

Economic Evaluation of Laboratory Testing Strategies for Hospital-Associated Clostridium difficile Infection

PubMed Central

Robilotti, Elizabeth; Peterson, Lance R.; Banaei, Niaz; Dowdy, David W.

2014-01-01

Clostridium difficile infection (CDI) is the most common cause of infectious diarrhea in health care settings, and for patients presumed to have CDI, their isolation while awaiting laboratory results is costly. Newer rapid tests for CDI may reduce this burden, but the economic consequences of different testing algorithms remain unexplored. We used decision analysis from the hospital perspective to compare multiple CDI testing algorithms for adult inpatients with suspected CDI, assuming patient management according to laboratory results. CDI testing strategies included combinations of on-demand PCR (odPCR), batch PCR, lateral-flow diagnostics, plate-reader enzyme immunoassay, and direct tissue culture cytotoxicity. In the reference scenario, algorithms incorporating rapid testing were cost-effective relative to nonrapid algorithms. For every 10,000 symptomatic adults, relative to a strategy of treating nobody, lateral-flow glutamate dehydrogenase (GDH)/odPCR generated 831 true-positive results and cost $1,600 per additional true-positive case treated. Stand-alone odPCR was more effective and more expensive, identifying 174 additional true-positive cases at $6,900 per additional case treated. All other testing strategies were dominated by (i.e., more costly and less effective than) stand-alone odPCR or odPCR preceded by lateral-flow screening. A cost-benefit analysis (including estimated costs of missed cases) favored stand-alone odPCR in most settings but favored odPCR preceded by lateral-flow testing if a missed CDI case resulted in less than $5,000 of extended hospital stay costs and <2 transmissions, if lateral-flow GDH diagnostic sensitivity was >93%, or if the symptomatic carrier proportion among the toxigenic culture-positive cases was >80%. These results can aid guideline developers and laboratory directors who are considering rapid testing algorithms for diagnosing CDI. PMID:24478478

A Revised Spanish/English Oral Proficiency Test, 1974 Field Test Results. Research and Development Memorandum No. 134.

ERIC Educational Resources Information Center

Ramirez, Arnulfo G.; Politzer, Robert L.

A revised Spanish/English oral-proficiency test battery was administered to 40 Spanish-surnamed pupils equally divided by sex at grade levels 1, 3, 5, and 7. The test battery included parallel Spanish and English versions of: (1) a 12-item vocabulary pretest, (2) a 32-item vocabulary-by-domain test consisting of four sections--home, neighborhood,…

Advanced Pediatric Brain Imaging Research and Training Program

DTIC Science & Technology

2015-10-01

post assessment scores (combined pretest AVG =64.5% to combined post - test AVG=94.04%). The scores demonstrate that online...techniques. This field test (s) included a (pre/ post : pre- test vs. post - test ) mixed design , with training being a between-subjects factor. We randomly... Post Test 98.0% The next section focuses on discussing the post -module survey results in which participants documented their

A program for calculating expansion-tube flow quantities for real-gas mixtures and comparison with experimental results

NASA Technical Reports Server (NTRS)

Miller, C. G., III

1972-01-01

A computer program written in FORTRAN 4 language is presented which determines expansion-tube flow quantities for real test gases CO2 N2, O2, Ar, He, and H2, or mixtures of these gases, in thermochemical equilibrium. The effects of dissociation and first and second ionization are included. Flow quantities behind the incident shock into the quiescent test gas are determined from the pressure and temperature of the quiescent test gas in conjunction with: (1) incident-shock velocity, (2) static pressure immediately behind the incident shock, or (3) pressure and temperature of the driver gas (imperfect hydrogen or helium). The effect of the possible existence of a shock reflection at the secondary diaphragm of the expansion tube is included. Expansion-tube test-section flow conditions are obtained by performing an isentropic unsteady expansion from the conditions behind the incident shock or reflected shock to either the test-region velocity or the static pressure. Both a thermochemical-equilibrium expansion and a frozen expansion are included. Flow conditions immediately behind the bow shock of a model positioned at the test section are also determined. Results from the program are compared with preliminary experimental data obtained in the Langley 6-inch expansion tube.

[The effects of moderate physical exercise on cognition in adults over 60 years of age].

PubMed

Sanchez-Gonzalez, J L; Calvo-Arenillas, J I; Sanchez-Rodriguez, J L

2018-04-01

Clinical evidence gathered in recent years indicates that elderly individuals more frequently display cognitive changes. These age-related changes refer, above all, to memory functions and to the speed of thinking and reasoning. A number of studies have shown that physical activity can be used as an important mechanism for protecting the cognitive functions. To test the hypothesis that physical exercise is able to bring about changes in the cognitive functions of healthy elderly adults without cognitive impairment, thereby improving their quality of life. The study population included participants in the University of Salamanca geriatric revitalisation programme. The sample initially consisted of a total of 44 subjects of both sexes, with a mean age of 74.93 years. The neuropsychological evaluation of the subjects included a series of validated neuropsychological tests: Mini-Mental State Examination, Benton Visual Retention Test, Rey Auditory Verbal Learning Test, Stroop Test and Trail Making Test. The results show that more physical activity is related to better performance in the cognitive functions of the subjects included in this study, after applying the geriatric revitalisation programme. The geriatric revitalisation programme can be a valuable tool for improving cognition in adults over 60 years of age, resulting in enhanced well-being in their quality of life.

Status and future plans of the Drones for Aerodynamic and Structural Testing (DAST) program. [Aeroelastic Research Wing (ARW)

NASA Technical Reports Server (NTRS)

Murrow, H. N.

1981-01-01

Results from flight tests of the ARW-1 research wing are presented. Preliminary loads data and experiences with the active control system for flutter suppression are included along with comparative results of test and prediction for the flutter boundary of the supercritical research wing and on performance of the flutter suppression system. The status of the ARW-2 research wing is given.

Design verification test matrix development for the STME thrust chamber assembly

NASA Technical Reports Server (NTRS)

Dexter, Carol E.; Elam, Sandra K.; Sparks, David L.

1993-01-01

This report presents the results of the test matrix development for design verification at the component level for the National Launch System (NLS) space transportation main engine (STME) thrust chamber assembly (TCA) components including the following: injector, combustion chamber, and nozzle. A systematic approach was used in the development of the minimum recommended TCA matrix resulting in a minimum number of hardware units and a minimum number of hot fire tests.

The Behind-the-Knee test: an efficient model for evaluating mechanical and chemical irritation.

PubMed

Farage, Miranda A

2006-05-01

The 'Behind-the-Knee' method (BTK test), using the popliteal fossa as a test site, evaluates both the inherent chemical irritation, and the potential for mechanical irritation of substrates and products. This approach eliminates some of the difficulties of in-use clinical test systems while still providing reliable results. In this publication, examples of the results of BTK tests on several materials are presented with direct comparisons, where possible, with results of in-use clinical testing conducted on the same materials. In in-use clinical tests, volunteer panelists were provided with catamenial products to use in place of their normal product. In the BTK test, samples were applied daily to the popliteal fossa using an elastic athletic band. In both studies, irritation reactions were scored visually. Levels of irritation in the BTK test are consistently higher than those of standard patch tests, illustrating the contribution of mechanical irritation to the overall irritant potential of materials and products. Repeated tests on identical test materials demonstrated that the BTK test results are reproducible. Side-by-side comparisons of the BTK test and in-use clinical tests demonstrated that the BTK test produces results of similar quality to the in-use clinical. By using several concurrent panels with a common test material, it is possible to compare the irritant properties of several materials at once. We have tested over 25 different materials in over 35 BTK studies. The test method has proven reliable and versatile in testing a wide variety of materials, including menstrual pads, topsheets, interlabial pads, pantiliners, tampons and lotion coatings on products. Unlike in-use clinicals, the BTK test allows the direct comparison of two products at one time on the same individual, and is easily adapted to investigative programs. It is subject to fewer confounding factors, is much easier to implement, has a shorter turnaround time, and is less expensive than in-use clinical testing. Importantly, unlike standard patch tests, the BTK test evaluates both the inherent chemical irritation associated with materials and the mechanical irritation owing to friction. Although the BTK test was developed using catamenial products, the test system provides a valuable alternative for evaluating any material where mechanical irritation may play a role, including textiles, facial tissues, baby and adult diapers, and laundry products that may leave residues on fabrics.

Technical Evaluation Motor No. 7 (TEM-07)

NASA Technical Reports Server (NTRS)

Hugh, Phil

1991-01-01

Technical Evaluation Motor Number 7 (TEM-7) was a full scale, full-duration static test firing of a high performance motor (HPM) configuration solid rocket motor (SRM) with nozzle vectoring. The static test fire occurred on 11 December 1990 at the Thiokol Corporation Static Test Bay T-97. Documented here are the procedures, performance, and results available through 22 January 1991. Critical post test hardware activities and assessment of the test data are not complete. A completed test report will be submitted 60 days after the test date. Included here is a presentation and discussion of the TEM-7 performance, anomalies, and test result concurrence with the objectives outlined in CTP-0107 Revision A, Space Shuttle Technical Evaluation Motor number 7 (TEM-07) Static Fire Test Plan.

Accelerated stress testing of terrestrial solar cells

NASA Technical Reports Server (NTRS)

Lathrop, J. W.; Hawkins, D. C.; Prince, J. L.; Walker, H. A.

1982-01-01

The development of an accelerated test schedule for terrestrial solar cells is described. This schedule, based on anticipated failure modes deduced from a consideration of IC failure mechanisms, involves bias-temperature testing, humidity testing (including both 85-85 and pressure cooker stress), and thermal-cycle thermal-shock testing. Results are described for 12 different unencapsulated cell types. Both gradual electrical degradation and sudden catastrophic mechanical change were observed. These effects can be used to discriminate between cell types and technologies relative to their reliability attributes. Consideration is given to identifying laboratory failure modes which might lead to severe degradation in the field through second quadrant operation. Test results indicate that the ability of most cell types to withstand accelerated stress testing depends more on the manufacturer's design, processing, and worksmanship than on the particular metallization system. Preliminary tests comparing accelerated test results on encapsulated and unencapsulated cells are described.

Personal Narratives of Genetic Testing: Expectations, Emotions, and Impact on Self and Family.

PubMed

Anderson, Emily E; Wasson, Katherine

2015-01-01

The stories in this volume shed light on the potential of narrative inquiry to fill gaps in knowledge, particularly given the mixed results of quantitative research on patient views of and experiences with genetic and genomic testing. Published studies investigate predictors of testing (particularly risk perceptions and worry); psychological and behavioral responses to testing; and potential impact on the health care system (e.g., when patients bring DTC genetic test results to their primary care provider). Interestingly, these themes did not dominate the narratives published in this issue. Rather, these narratives included consistent themes of expectations and looking for answers; complex emotions; areas of contradiction and conflict; and family impact. More narrative research on patient experiences with genetic testing may fill gaps in knowledge regarding how patients define the benefits of testing, changes in psychological and emotional reactions to test results over time, and the impact of testing on families.

Study of Dominant Factors Affecting Cerchar Abrasivity Index

NASA Astrophysics Data System (ADS)

Rostami, Jamal; Ghasemi, Amireza; Alavi Gharahbagh, Ehsan; Dogruoz, Cihan; Dahl, Filip

2014-09-01

The Cerchar abrasion index is commonly used to represent rock abrasion for estimation of bit life and wear in various mining and tunneling applications. Although the test is simple and fast, there are some discrepancies in the test results related to the equipment used, condition of the rock surface, operator skills, and procedures used in conducting and measuring the wear surface. This paper focuses on the background of the test and examines the influence of various parameters on Cerchar testing including pin hardness, surface condition of specimens, petrographical and geomechanical properties, test speed, applied load, and method of measuring wear surface. Results of Cerchar tests on a set of rock specimens performed at different laboratories are presented to examine repeatability of the tests. In addition, the preliminary results of testing with a new device as a potential alternative testing system for rock abrasivity measurement are discussed.

Diagnosis of Acute Gout: A Clinical Practice Guideline From the American College of Physicians.

PubMed

Qaseem, Amir; McLean, Robert M; Starkey, Melissa; Forciea, Mary Ann

2017-01-03

The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on the diagnosis of gout. This guideline is based on a systematic review of published studies on gout diagnosis, identified using several databases, from database inception to February 2016. Evaluated outcomes included the accuracy of the test results; intermediate outcomes (results of laboratory and radiographic tests, such as serum urate and synovial fluid crystal analysis and radiographic or ultrasonography changes); clinical decision making (additional testing and pharmacologic or dietary management); short-term clinical (patient-centered) outcomes, such as pain and joint swelling and tenderness; and adverse effects of the tests. This guideline grades the evidence and recommendations by using the ACP grading system, which is based on the GRADE (Grading of Recommendations Assessment, Development and Evaluation) method. The target audience for this guideline includes all clinicians, and the target patient population includes adults with joint inflammation suspected to be gout. ACP recommends that clinicians use synovial fluid analysis when clinical judgment indicates that diagnostic testing is necessary in patients with possible acute gout. (Grade: weak recommendation, low-quality evidence).

Construction and beam-tests of silicon-tungsten prototype modules for the CMS High Granularity Calorimeter for HL-LHC

NASA Astrophysics Data System (ADS)

Quast, Thorben

2018-02-01

As part of its HL-LHC upgrade program, CMS is developing a High Granularity Calorimeter (HGCAL) to replace the existing endcap calorimeters. The HGCAL will be realised as a sampling calorimeter, including an electromagnetic compartment comprising 28 layers of silicon pad detectors with pad areas of 0.5-1.0 cm2 interspersed with absorbers. Prototype modules, based on 6-inch hexagonal silicon pad sensors with 128 channels, have been constructed and include many of the features required for this challenging detector. In 2016, beam tests of sampling configurations made from these modules have been conducted both at FNAL and at CERN using the Skiroc2 front-end ASIC (designed by the CALICE collaboration for ILC). In 2017, the setup has been extended with CALICE's AHCAL prototype, a scinitillator based sampling calorimeter, and it was further tested in dedicated beam tests at CERN. There, the new Skiroc2-CMS front-end ASIC was used for the first time. We highlight final results from our studies in 2016, including position resolution as well as precision timing-measurements. Furthermore, the extended setup in 2017 is discussed and first results from beam tests with electrons and pions are shown.

Clinical and Microbiological Aspects of β-Lactam Resistance in Staphylococcus lugdunensis

PubMed Central

McHardy, Ian H.; Veltman, Jennifer; Hindler, Janet; Bruxvoort, Katia; Carvalho, Marissa M.

2016-01-01

ABSTRACT Antimicrobial susceptibility results from broth microdilution MIC testing of 993 Staphylococcus lugdunensis isolates recovered from patients at a tertiary care medical center from 2008 to 2015 were reviewed. Ninety-two oxacillin-susceptible isolates were selected to assess the accuracy of penicillin MIC testing, the penicillin disk diffusion test, and three β-lactamase tests, including the cefoxitin-induced nitrocefin test, penicillin cloverleaf assay, and penicillin disk zone edge test. The results of all phenotypic tests were compared to the results of blaZ PCR. The medical records of 62 patients from whom S. lugdunensis was isolated, including 31 penicillin-susceptible and 31 penicillin-resistant strains, were retrospectively reviewed to evaluate the clinical significance of S. lugdunensis isolation, the antimicrobial agents prescribed, if any, and the clinical outcome. MIC testing revealed that 517/993 (52.1%) isolates were susceptible to penicillin and 946/993 (95.3%) were susceptible to oxacillin. The induced nitrocefin test was 100% sensitive and specific for the detection of β-lactamase compared to the blaZ PCR results, whereas the penicillin disk zone edge and cloverleaf tests showed sensitivities of 100% but specificities of only 9.1% and 89.1%, respectively. The penicillin MIC test had 100% categorical agreement with blaZ PCR, while penicillin disk diffusion yielded one major error. Only 3/31 patients with penicillin-susceptible isolates were treated with a penicillin family antimicrobial. The majority of cases were treated with other β-lactams, trimethoprim-sulfamethoxazole, or vancomycin. These data indicate that nearly all isolates of S. lugdunensis are susceptible to narrow-spectrum antimicrobial agents. Clinical laboratories in areas with resistance levels similar to those described here can help promote the use of these agents versus vancomycin by effectively designing their antimicrobial susceptibility reports to convey this message. PMID:27927926

Clinical and Microbiological Aspects of β-Lactam Resistance in Staphylococcus lugdunensis.

PubMed

McHardy, Ian H; Veltman, Jennifer; Hindler, Janet; Bruxvoort, Katia; Carvalho, Marissa M; Humphries, Romney M

2017-02-01

Antimicrobial susceptibility results from broth microdilution MIC testing of 993 Staphylococcus lugdunensis isolates recovered from patients at a tertiary care medical center from 2008 to 2015 were reviewed. Ninety-two oxacillin-susceptible isolates were selected to assess the accuracy of penicillin MIC testing, the penicillin disk diffusion test, and three β-lactamase tests, including the cefoxitin-induced nitrocefin test, penicillin cloverleaf assay, and penicillin disk zone edge test. The results of all phenotypic tests were compared to the results of blaZ PCR. The medical records of 62 patients from whom S. lugdunensis was isolated, including 31 penicillin-susceptible and 31 penicillin-resistant strains, were retrospectively reviewed to evaluate the clinical significance of S. lugdunensis isolation, the antimicrobial agents prescribed, if any, and the clinical outcome. MIC testing revealed that 517/993 (52.1%) isolates were susceptible to penicillin and 946/993 (95.3%) were susceptible to oxacillin. The induced nitrocefin test was 100% sensitive and specific for the detection of β-lactamase compared to the blaZ PCR results, whereas the penicillin disk zone edge and cloverleaf tests showed sensitivities of 100% but specificities of only 9.1% and 89.1%, respectively. The penicillin MIC test had 100% categorical agreement with blaZ PCR, while penicillin disk diffusion yielded one major error. Only 3/31 patients with penicillin-susceptible isolates were treated with a penicillin family antimicrobial. The majority of cases were treated with other β-lactams, trimethoprim-sulfamethoxazole, or vancomycin. These data indicate that nearly all isolates of S. lugdunensis are susceptible to narrow-spectrum antimicrobial agents. Clinical laboratories in areas with resistance levels similar to those described here can help promote the use of these agents versus vancomycin by effectively designing their antimicrobial susceptibility reports to convey this message. Copyright © 2017 American Society for Microbiology.

FY17 Status Report on Testing Supporting the Inclusion of Grade 91 Steel as an Acceptable Material for Application of the EPP Methodology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Messner, Mark C.; Sham, Sam; Wang, Yanli

This report summarizes the experiments performed in FY17 on Gr. 91 steels. The testing of Gr. 91 has technical significance because, currently, it is the only approved material for Class A construction that is strongly cyclic softening. Specific FY17 testing includes the following activities for Gr. 91 steel. First, two types of key feature testing have been initiated, including two-bar thermal ratcheting and Simplified Model Testing (SMT). The goal is to qualify the Elastic – Perfectly Plastic (EPP) design methodologies and to support incorporation of these rules for Gr. 91 into the ASME Division 5 Code. The preliminary SMT testmore » results show that Gr. 91 is most damaging when tested with compression hold mode under the SMT creep fatigue testing condition. Two-bar thermal ratcheting test results at a temperature range between 350 to 650o C were compared with the EPP strain limits code case evaluation, and the results show that the EPP strain limits code case is conservative. The material information obtained from these key feature tests can also be used to verify its material model. Second, to provide experimental data in support of the viscoplastic material model development at Argonne National Laboratory, selective tests were performed to evaluate the effect of cyclic softening on strain rate sensitivity and creep rates. The results show the prior cyclic loading history decreases the strain rate sensitivity and increases creep rates. In addition, isothermal cyclic stress-strain curves were generated at six different temperatures, and a nonisothermal thermomechanical testing was also performed to provide data to calibrate the viscoplastic material model.« less

Visualizing the Bayesian 2-test case: The effect of tree diagrams on medical decision making.

PubMed

Binder, Karin; Krauss, Stefan; Bruckmaier, Georg; Marienhagen, Jörg

2018-01-01

In medicine, diagnoses based on medical test results are probabilistic by nature. Unfortunately, cognitive illusions regarding the statistical meaning of test results are well documented among patients, medical students, and even physicians. There are two effective strategies that can foster insight into what is known as Bayesian reasoning situations: (1) translating the statistical information on the prevalence of a disease and the sensitivity and the false-alarm rate of a specific test for that disease from probabilities into natural frequencies, and (2) illustrating the statistical information with tree diagrams, for instance, or with other pictorial representation. So far, such strategies have only been empirically tested in combination for "1-test cases", where one binary hypothesis ("disease" vs. "no disease") has to be diagnosed based on one binary test result ("positive" vs. "negative"). However, in reality, often more than one medical test is conducted to derive a diagnosis. In two studies, we examined a total of 388 medical students from the University of Regensburg (Germany) with medical "2-test scenarios". Each student had to work on two problems: diagnosing breast cancer with mammography and sonography test results, and diagnosing HIV infection with the ELISA and Western Blot tests. In Study 1 (N = 190 participants), we systematically varied the presentation of statistical information ("only textual information" vs. "only tree diagram" vs. "text and tree diagram in combination"), whereas in Study 2 (N = 198 participants), we varied the kinds of tree diagrams ("complete tree" vs. "highlighted tree" vs. "pruned tree"). All versions were implemented in probability format (including probability trees) and in natural frequency format (including frequency trees). We found that natural frequency trees, especially when the question-related branches were highlighted, improved performance, but that none of the corresponding probabilistic visualizations did.

Rapid tests for the diagnosis of visceral leishmaniasis in patients with suspected disease

PubMed Central

Boelaert, Marleen; Verdonck, Kristien; Menten, Joris; Sunyoto, Temmy; van Griensven, Johan; Chappuis, Francois; Rijal, Suman

2014-01-01

Background The diagnosis of visceral leishmaniasis (VL) in patients with fever and a large spleen relies on showing Leishmania parasites in tissue samples and on serological tests. Parasitological techniques are invasive, require sophisticated laboratories, consume time, or lack accuracy. Recently, rapid diagnostic tests that are easy to perform have become available. Objectives To determine the diagnostic accuracy of rapid tests for diagnosing VL in patients with suspected disease presenting at health services in endemic areas. Search methods We searched MEDLINE, EMBASE, LILACS, CIDG SR, CENTRAL, SCI-expanded, Medion, Arif, CCT, and the WHO trials register on 3 December 2013, without applying language or date limits. Selection criteria This review includes original, phase III, diagnostic accuracy studies of rapid tests in patients clinically suspected to have VL. As reference standards, we accepted: (1) direct smear or culture of spleen aspirate; (2) composite reference standard based on one or more of the following: parasitology, serology, or response to treatment; and (3) latent class analysis. Data collection and analysis Two review authors independently extracted data and assessed quality of included studies using the QUADAS-2 tool. Discrepancies were resolved by a third author. We carried out a meta-analysis to estimate sensitivity and specificity of rapid tests, using a bivariate normal model with a complementary log-log link function. We analysed each index test separately. As possible sources of heterogeneity, we explored: geographical area, commercial brand of index test, type of reference standard, disease prevalence, study size, and risk of bias (QUADAS-2). We also undertook a sensitivity analysis to assess the influence of imperfect reference standards. Main results Twenty-four studies containing information about five index tests (rK39 immunochromatographic test (ICT), KAtex latex agglutination test in urine, FAST agglutination test, rK26 ICT, and rKE16 ICT) recruiting 4271 participants (2605 with VL) were included. We carried out a meta-analysis for the rK39 ICT (including 18 studies; 3622 participants) and the latex agglutination test (six studies; 1374 participants). The results showed considerable heterogeneity. For the rK39 ICT, the overall sensitivity was 91.9% (95% confidence interval (95% CI) 84.8 to 96.5) and the specificity 92.4% (95% CI 85.6 to 96.8). The sensitivity was lower in East Africa (85.3%; 95% CI 74.5 to 93.2) than in the Indian subcontinent (97.0%; 95% CI 90.0 to 99.5). For the latex agglutination test, overall sensitivity was 63.6% (95% CI 40.9 to 85.6) and specificity 92.9% (95% CI 76.7 to 99.2). Authors' conclusions The rK39 ICT shows high sensitivity and specificity for the diagnosis of visceral leishmaniasis in patients with febrile splenomegaly and no previous history of the disease, but the sensitivity is notably lower in east Africa than in the Indian subcontinent. Other rapid tests lack accuracy, validation, or both. PLAIN LANGUAGE SUMMARY Rapid diagnostic tests for visceral leishmaniasis Visceral leishmaniasis (or kala-azar) is caused by a parasite, results in fever, a large spleen and other health problems, occuring in India, Bangladesh and Nepal, east Africa, the Mediterranean region and Brazil. Without treatment people die, and proper treatment can result in cure, so diagnosis is important. Many of the tests that are used to determine if a person has visceral leishmaniasis are complicated, costly, painful and sometimes dangerous for the patients. Now rapid diagnostic tests that are safe and easy to perform are available. This Cochrane review describes how accurate these rapid diagnostic tests are for diagnosing visceral leishmaniasis. We summarize those studies that evaluated the rapid tests in people who, according to their physicians, could have the disease. We only included studies in which the researchers had used established methods to distinguish the people with visceral leishmaniasis from those who did not have the disease. We found 24 studies, which contained information about five different rapid tests. A total of 4271 people participated in these studies. One of the rapid tests (called the rK39 immunochromatographic test) gave correct, positive results in 92% of the people with visceral leishmaniasis and it gave correct, negative results in 92% of the people who did not have the disease. This test worked better in India and Nepal than in east Africa. In India and Nepal, it gave correct, positive results in 97% of the people with the disease. In east Africa, it gave correct, positive results in only 85% of the people with the disease. A second rapid test (called latex agglutination test) gave correct, positive results in 64% of the people with the disease and it gave correct, negative results in 93% of the people without the disease. For the other rapid tests evaluated, there are too few studies to know how accurate they are. PMID:24947503

HIV Risk Perception and Behavior among Sex Workers in Three Major Urban Centers of Mozambique

PubMed Central

Langa, Judite; Sousa, César; Sidat, Mohsin; Kroeger, Karen; McLellan-Lemal, Eleanor; Belani, Hrishikesh; Patel, Shama; Shodell, Daniel; Shodell, Michael; Benech, Irene; Needle, Richard

2014-01-01

HIV risk perceptions and behaviors of 236 commercial sex workers from three major Mozambican urban centers were studied using the International Rapid Assessment, Response and Evaluation (I-RARE) methodology. All were offered HIV testing and, in Maputo, syphilis testing was offered as well. Sixty-three of the 236 opted for HIV testing, with 30 (48%) testing positive for HIV. In Maputo, all 30 receiving HIV tests also had syphilis testing, with 6 (20%) found to be positive. Results include interview excerpts and qualitative results using I-RARE methodology and AnSWR-assisted analyses of the interviews and focus group sessions. PMID:24736653

Endurance testing of a 30-cm Kaufman thruster

NASA Technical Reports Server (NTRS)

Collett, C. R.

1973-01-01

Results of a program to demonstrate lifetime capability of a 30-cm Kaufman ion thruster with a 6000 hour endurance test are described. Included in the program are (1) thruster fabrication, (2) design and construction of a test console containing a transistorized high frequency power processor, and control circuits which provide unattended automatic operation of the thruster, and (3) modification of a vacuum facility to incorporate a frozen mercury collector and permit unattended operation. Four tests ranging in duration from 100 to 1100 hours have been completed. These tests and the resulting thruster modifications are described. The status of the endurance test is also presented.

Autohesive strength development in polysulfone resin and graphite-polysulfone composites

NASA Technical Reports Server (NTRS)

Howes, Jeremy C.; Loos, Alfred C.

1988-01-01

The effects of bonding temperature and contact time on autohesive strength development in thermoplastic polysulfone resin and graphite-polysulfone composites were investigated. Two test methods were examined to measure autohesion in the neat resin samples. These included an interfacial tension test and a compact tension fracture toughness test. Autohesive strength development in fiber-reinforced composites was measured using a double cantilever beam interlaminar fracture toughness test. The results of the tests were compared with current diffusion theories explaining crack healing and welding of glassy polymers. Discrepancies between the results of the present investigation and the diffusion theories are discussed.

LSA field test

NASA Technical Reports Server (NTRS)

Jaffe, P.

1979-01-01

Degradation tests indicate that electrical degradation is not a slow monotonically increasing phenomenon as originally thought but occurs abruptly as the result of some traumatic event. This finding has led to a change in the test philosophy. A discussion of this change is presented along with a summary of degradation and failure data from all the sites and results from a variety of special tests. New instrumentation for in-field measurements are described. Field testing activity was expanded by the addition of twelve remote sites located as far away as Alaska and the Canal Zone. Descriptions of the new sites are included.

Rover nuclear rocket engine program: Overview of rover engine tests

NASA Technical Reports Server (NTRS)

Finseth, J. L.

1991-01-01

The results of nuclear rocket development activities from the inception of the ROVER program in 1955 through the termination of activities on January 5, 1973 are summarized. This report discusses the nuclear reactor test configurations (non cold flow) along with the nuclear furnace demonstrated during this time frame. Included in the report are brief descriptions of the propulsion systems, test objectives, accomplishments, technical issues, and relevant test results for the various reactor tests. Additionally, this document is specifically aimed at reporting performance data and their relationship to fuel element development with little or no emphasis on other (important) items.

Large-Scale Wind-Tunnel Tests of an Airplane Model with an Unswept, Tilt Wing of Aspect Ratio 5.5, and with Four Propellers and Blowing Flaps

NASA Technical Reports Server (NTRS)

Weiberg, James A.; Holzhauser, Curt A.

1961-01-01

Tests were made of a large-scale tilt-wing deflected-slipstream VTOL airplane with blowing-type BLC trailing-edge flaps. The model was tested with flap deflections of 0 deg. without BLC, 50 deg. with and without BLC, and 80 deg. with BLC for wing-tilt angles of 0, 30, and 50 deg. Included are results of tests of the model equipped with a leading-edge flap and the results of tests of the model in the presence of a ground plane.

Bias in the physical examination of patients with lumbar radiculopathy

PubMed Central

2010-01-01

Background No prior studies have examined systematic bias in the musculoskeletal physical examination. The objective of this study was to assess the effects of bias due to prior knowledge of lumbar spine magnetic resonance imaging findings (MRI) on perceived diagnostic accuracy of the physical examination for lumbar radiculopathy. Methods This was a cross-sectional comparison of the performance characteristics of the physical examination with blinding to MRI results (the 'independent group') with performance in the situation where the physical examination was not blinded to MRI results (the 'non-independent group'). The reference standard was the final diagnostic impression of nerve root impingement by the examining physician. Subjects were recruited from a hospital-based outpatient specialty spine clinic. All adults age 18 and older presenting with lower extremity radiating pain of duration ≤ 12 weeks were evaluated for participation. 154 consecutively recruited subjects with lumbar disk herniation confirmed by lumbar spine MRI were included in this study. Sensitivities and specificities with 95% confidence intervals were calculated in the independent and non-independent groups for the four components of the radiculopathy examination: 1) provocative testing, 2) motor strength testing, 3) pinprick sensory testing, and 4) deep tendon reflex testing. Results The perceived sensitivity of sensory testing was higher with prior knowledge of MRI results (20% vs. 36%; p = 0.05). Sensitivities and specificities for exam components otherwise showed no statistically significant differences between groups. Conclusions Prior knowledge of lumbar MRI results may introduce bias into the pinprick sensory testing component of the physical examination for lumbar radiculopathy. No statistically significant effect of bias was seen for other components of the physical examination. The effect of bias due to prior knowledge of lumbar MRI results should be considered when an isolated sensory deficit on examination is used in medical decision-making. Further studies of bias should include surgical clinic populations and other common diagnoses including shoulder, knee and hip pathology. PMID:21118558

EGFR T790M mutation testing within the osimertinib AURA Phase I study.

PubMed

Dearden, Simon; Brown, Helen; Jenkins, Suzanne; Thress, Kenneth S; Cantarini, Mireille; Cole, Rebecca; Ranson, Malcolm; Jänne, Pasi A

2017-07-01

Reliable epidermal growth factor receptor (EGFR) mutation testing techniques are required to identify eligible patients with EGFR mutation/T790M positive advanced non-small cell lung cancer (NSCLC), for treatment with osimertinib (AZD9291), an oral, potent, irreversible EGFR tyrosine kinase inhibitor (TKI) selective for EGFR-TKI-sensitizing and T790M resistance mutations over wild-type EGFR. There is no current consensus regarding the best method to detect EGFR T790M mutations. The aim of this study was to describe the concordance between local testing, which used a variety of methods, and central testing, using the cobas ® EGFR Mutation Test, for EGFR-sensitizing mutations and the T790M resistance mutation. Tumor samples were obtained from all patients screened for inclusion onto the osimertinib Phase I expansion component of the AURA Phase I/II study (NCT01802632). Samples underwent central laboratory testing for EGFR-sensitizing mutations and T790M resistance mutation using the cobas ® EGFR Mutation Test. Results were compared with local laboratory test results, based on other testing methodologies including Sanger sequencing, therascreen ® , PNAClamp™, and Sequenom MassARRAY ® . Central laboratory testing was successful in 99% of samples passing histopathology review and testing success rates were comparable across the three central laboratories. Concordance between central and local testing for common sensitizing mutations was high (>98%) and concordance for the T790M mutation was also high (>90%). Tumor heterogeneity, along with other technical factors may have influenced this result. Within the osimertinib AURA Phase I study, EGFR mutation testing across three centralized laboratories using the cobas ® EGFR Mutation Test was feasible and successful, with strong concordance between local and central laboratory results, including for T790M. The cobas ® EGFR Mutation Test has subsequently been approved as the companion diagnostic test for osimertinib in the USA and Japan. Copyright © 2017 Elsevier B.V. All rights reserved.

Outcomes Definitions and Statistical Tests in Oncology Studies: A Systematic Review of the Reporting Consistency

PubMed Central

Rivoirard, Romain; Duplay, Vianney; Oriol, Mathieu; Tinquaut, Fabien; Chauvin, Franck; Magne, Nicolas; Bourmaud, Aurelie

2016-01-01

Background Quality of reporting for Randomized Clinical Trials (RCTs) in oncology was analyzed in several systematic reviews, but, in this setting, there is paucity of data for the outcomes definitions and consistency of reporting for statistical tests in RCTs and Observational Studies (OBS). The objective of this review was to describe those two reporting aspects, for OBS and RCTs in oncology. Methods From a list of 19 medical journals, three were retained for analysis, after a random selection: British Medical Journal (BMJ), Annals of Oncology (AoO) and British Journal of Cancer (BJC). All original articles published between March 2009 and March 2014 were screened. Only studies whose main outcome was accompanied by a corresponding statistical test were included in the analysis. Studies based on censored data were excluded. Primary outcome was to assess quality of reporting for description of primary outcome measure in RCTs and of variables of interest in OBS. A logistic regression was performed to identify covariates of studies potentially associated with concordance of tests between Methods and Results parts. Results 826 studies were included in the review, and 698 were OBS. Variables were described in Methods section for all OBS studies and primary endpoint was clearly detailed in Methods section for 109 RCTs (85.2%). 295 OBS (42.2%) and 43 RCTs (33.6%) had perfect agreement for reported statistical test between Methods and Results parts. In multivariable analysis, variable "number of included patients in study" was associated with test consistency: aOR (adjusted Odds Ratio) for third group compared to first group was equal to: aOR Grp3 = 0.52 [0.31–0.89] (P value = 0.009). Conclusion Variables in OBS and primary endpoint in RCTs are reported and described with a high frequency. However, statistical tests consistency between methods and Results sections of OBS is not always noted. Therefore, we encourage authors and peer reviewers to verify consistency of statistical tests in oncology studies. PMID:27716793

Space Station Freedom environmental control and life support system phase 3 simplified integrated test detailed report

NASA Technical Reports Server (NTRS)

Roberts, B. C.; Carrasquillo, R. L.; Dubiel, M. Y.; Ogle, K. Y.; Perry, J. L.; Whitley, K. M.

1990-01-01

A description of the phase 3 simplified integrated test (SIT) conducted at the Marshall Space Flight Center (MSFC) Core Module Integration Facility (CMIF) in 1989 is presented. This was the first test in the phase 3 series integrated environmental control and life support systems (ECLSS) tests. The basic goal of the SIT was to achieve full integration of the baseline air revitalization (AR) subsystems for Space Station Freedom. Included is a description of the SIT configuration, a performance analysis of each subsystem, results from air and water sampling, and a discussion of lessons learned from the test. Also included is a full description of the preprototype ECLSS hardware used in the test.

40 CFR Appendix B to Part 60 - Performance Specifications

Code of Federal Regulations, 2012 CFR

2012-07-01

... manufacturers comply with a comprehensive series of design and performance specifications and test procedures to... must periodically select and test an opacity monitor, that is representative of a group of monitors... program are used. One Run may include results for more than one test condition. Constant emissions means...

40 CFR Appendix B to Part 60 - Performance Specifications

Code of Federal Regulations, 2011 CFR

2011-07-01

... manufacturers comply with a comprehensive series of design and performance specifications and test procedures to... must periodically select and test an opacity monitor, that is representative of a group of monitors... program are used. One Run may include results for more than one test condition. Constant emissions means...

40 CFR Appendix B to Part 60 - Performance Specifications

Code of Federal Regulations, 2013 CFR

2013-07-01

... manufacturers comply with a comprehensive series of design and performance specifications and test procedures to... must periodically select and test an opacity monitor, that is representative of a group of monitors... program are used. One Run may include results for more than one test condition. Constant emissions means...

Validation of a Video-based Game-Understanding Test Procedure in Badminton.

ERIC Educational Resources Information Center

Blomqvist, Minna T.; Luhtanen, Pekka; Laakso, Lauri; Keskinen, Esko

2000-01-01

Reports the development and validation of video-based game-understanding tests in badminton for elementary and secondary students. The tests included different sequences that simulated actual game situations. Players had to solve tactical problems by selecting appropriate solutions and arguments for their decisions. Results suggest that the test…

Model aerodynamic test results for two variable cycle engine coannular exhaust systems at simulated takeoff and cruise conditions. Comprehensive data report. Volume 2: Tabulated aerodynamic data book 2

NASA Technical Reports Server (NTRS)

Nelson, D. P.

1981-01-01

Tabulated aerodynamic data from coannular nozzle performance tests are given for test runs 26 through 37. The data include nozzle thrust coefficient parameters, nozzle discharge coefficients, and static pressure tap measurements.

A Logic of Appropriation: Enacting National Testing (NAPLAN) in Australia

ERIC Educational Resources Information Center

Hardy, Ian

2014-01-01

This paper explores how the strong policy push to improve students' results on national literacy and numeracy tests -- the National Assessment Program, Literacy and Numeracy (NAPLAN) -- in the Australian state of Queensland influenced schooling practices, including teachers' learning. The paper argues the focus upon improved test scores on NAPLAN…

6 CFR 25.6 - Procedures for designation of qualified anti-terrorism technologies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... available or can be feasibly conducted or obtained, including test results produced by an independent laboratory or other entity engaged to test or verify the safety, utility, performance, in order to assess the...; (ii) Classified and otherwise confidential studies; (iii) Studies, tests, or other performance records...

6 CFR 25.6 - Procedures for designation of qualified anti-terrorism technologies.

Code of Federal Regulations, 2014 CFR

2014-01-01

... available or can be feasibly conducted or obtained, including test results produced by an independent laboratory or other entity engaged to test or verify the safety, utility, performance, in order to assess the...; (ii) Classified and otherwise confidential studies; (iii) Studies, tests, or other performance records...

Subscriber Response System. Progress Report.

ERIC Educational Resources Information Center

Callais, Richard T.

Results of preliminary tests made prior and subsequent to the installation of a two-way interactive communication system which involves a computer complex termed the Local Processing Center and subscriber terminals located in the home or business location are reported. This first phase of the overall test plan includes tests made at Theta-Com…

SU-F-T-475: An Evaluation of the Overlap Between the Acceptance Testing and Commissioning Processes for Conventional Medical Linear Accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morrow, A; Rangaraj, D; Perez-Andujar, A

2016-06-15

Purpose: This work’s objective is to determine the overlap of processes, in terms of sub-processes and time, between acceptance testing and commissioning of a conventional medical linear accelerator and to evaluate the time saved by consolidating the two processes. Method: A process map for acceptance testing for medical linear accelerators was created from vendor documentation (Varian and Elekta). Using AAPM TG-106 and inhouse commissioning procedures, a process map was created for commissioning of said accelerators. The time to complete each sub-process in each process map was evaluated. Redundancies in the processes were found and the time spent on each weremore » calculated. Results: Mechanical testing significantly overlaps between the two processes - redundant work here amounts to 9.5 hours. Many beam non-scanning dosimetry tests overlap resulting in another 6 hours of overlap. Beam scanning overlaps somewhat - acceptance tests include evaluating PDDs and multiple profiles but for only one field size while commissioning beam scanning includes multiple field sizes and depths of profiles. This overlap results in another 6 hours of rework. Absolute dosimetry, field outputs, and end to end tests are not done at all in acceptance testing. Finally, all imaging tests done in acceptance are repeated in commissioning, resulting in about 8 hours of rework. The total time overlap between the two processes is about 30 hours. Conclusion: The process mapping done in this study shows that there are no tests done in acceptance testing that are not also recommended to do for commissioning. This results in about 30 hours of redundant work when preparing a conventional linear accelerator for clinical use. Considering these findings in the context of the 5000 linacs in the United states, consolidating acceptance testing and commissioning would have allowed for the treatment of an additional 25000 patients using no additional resources.« less

Medical University admission test: a confirmatory factor analysis of the results.

PubMed

Luschin-Ebengreuth, Marion; Dimai, Hans P; Ithaler, Daniel; Neges, Heide M; Reibnegger, Gilbert

2016-05-01

The Graz Admission Test has been applied since the academic year 2006/2007. The validity of the Test was demonstrated by a significant improvement of study success and a significant reduction of dropout rate. The purpose of this study was a detailed analysis of the internal correlation structure of the various components of the Graz Admission Test. In particular, the question investigated was whether or not the various test parts constitute a suitable construct which might be designated as "Basic Knowledge in Natural Science." This study is an observational investigation, analyzing the results of the Graz Admission Test for the study of human medicine and dentistry. A total of 4741 applicants were included in the analysis. Principal component factor analysis (PCFA) as well as techniques from structural equation modeling, specifically confirmatory factor analysis (CFA), were employed to detect potential underlying latent variables governing the behavior of the measured variables. PCFA showed good clustering of the science test parts, including also text comprehension. A putative latent variable "Basic Knowledge in Natural Science," investigated by CFA, was indeed shown to govern the response behavior of the applicants in biology, chemistry, physics, and mathematics as well as text comprehension. The analysis of the correlation structure of the various test parts confirmed that the science test parts together with text comprehension constitute a satisfactory instrument for measuring a latent construct variable "Basic Knowledge in Natural Science." The present results suggest the fundamental importance of basic science knowledge for results obtained in the framework of the admission process for medical universities.

Polymer concrete overlay test program : final report.

DOT National Transportation Integrated Search

1981-12-01

The results in this report were obtained during the test program which began in 1973. Physical properties of various polymer concretes are listed. They include compressive strength, splitting tensile strength, bond strength, the modulus of elasticity...

A study of graphite-epoxy laminate failures due to high transverse shear strains using the multi-span-beam shear test procedure

NASA Technical Reports Server (NTRS)

Jegley, Dawn C.

1989-01-01

The multi-span-beam shear test procedure is used to study failure mechanisms in graphite-epoxy laminates due to high transverse shear strains induced by severe local bending deformations in test specimens. Results of a series of tests on specimens with a variety of stacking sequences, including some with adhesive interleaving, are presented. These results indicate that laminates with stacking sequences with several + or - 45 and 90 deg plies next to each other are more susceptible to failures due to high transverse shear strains than laminates with + or - 45 and 0 deg plies next to each other or with + or - 45 deg plies next to layers of adhesive interleaving. Results of these tests are compared with analytical results based on finite elements.

Summary of CPAS EDU Testing Analysis Results

NASA Technical Reports Server (NTRS)

Romero, Leah M.; Bledsoe, Kristin J.; Davidson, John.; Engert, Meagan E.; Fraire, Usbaldo, Jr.; Galaviz, Fernando S.; Galvin, Patrick J.; Ray, Eric S.; Varela, Jose

2015-01-01

The Orion program's Capsule Parachute Assembly System (CPAS) project is currently conducting its third generation of testing, the Engineering Development Unit (EDU) series. This series utilizes two test articles, a dart-shaped Parachute Compartment Drop Test Vehicle (PCDTV) and capsule-shaped Parachute Test Vehicle (PTV), both of which include a full size, flight-like parachute system and require a pallet delivery system for aircraft extraction. To date, 15 tests have been completed, including six with PCDTVs and nine with PTVs. Two of the PTV tests included the Forward Bay Cover (FBC) provided by Lockheed Martin. Advancements in modeling techniques applicable to parachute fly-out, vehicle rate of descent, torque, and load train, also occurred during the EDU testing series. An upgrade from a composite to an independent parachute simulation allowed parachute modeling at a higher level of fidelity than during previous generations. The complexity of separating the test vehicles from their pallet delivery systems necessitated the use the Automatic Dynamic Analysis of Mechanical Systems (ADAMS) simulator for modeling mated vehicle aircraft extraction and separation. This paper gives an overview of each EDU test and summarizes the development of CPAS analysis tools and techniques during EDU testing.

Programmable Logic Application Notes

NASA Technical Reports Server (NTRS)

Katz, Richard

1998-01-01

This column will be provided each quarter as a source for reliability, radiation results, NASA capabilities, and other information on programmable logic devices and related applications. This quarter's column will include some announcements and some recent radiation test results and evaluations of interest. Specifically, the following topics will be covered: the Military and Aerospace Applications of Programmable Devices and Technologies Conference to be held at GSFC in September, 1998, proton test results, and some total dose results.

The progress test as a diagnostic tool for a new PBL curriculum.

PubMed

Al Alwan, I; Al-Moamary, M; Al-Attas, N; Al Kushi, A; AlBanyan, E; Zamakhshary, M; Al Kadri, H M F; Tamim, H; Magzoub, M; Hajeer, A; Schmidt, H

2011-12-01

The College of Medicine at King Saud bin Abdulaziz University for Health Sciences (KSAU-HS) is running a PBL-based curriculum. A progress test was used to evaluate components of the basic medical and clinical sciences curriculum. To evaluate the performance of students at different levels of the college of medicine curriculum through USMLE-based test that focused on basic medical and clinical sciences topics. The USMLE-based basic medical and clinical sciences progress test has been conducted since 2007. It covers nine topics, including: anatomy; physiology; histology; epidemiology; biochemistry; behavioral sciences, pathology, pharmacology and immunology/microbiology. Here we analyzed results of three consecutive years of all students in years 1-4. There was a good correlation between progress test results and students' GPA. Progress test results in the clinical topics were better than basic medical sciences. In basic medical sciences, results of pharmacology, biochemistry, behavioral sciences and histology gave lower results than the other disciplines. Results of our progress test proved to be a useful indicator for both basic medical sciences and clinical sciences curriculum. Results are being utilized to help in modifying our curriculum.

Test of acoustic tone source and propulsion performance of C8A Buffalo suppressor nozzle

NASA Technical Reports Server (NTRS)

Marrs, C. C.; Harkonen, D. L.; Okeefe, J. V.

1974-01-01

Results are presented for a static acoustic and propulsion performance ground test conducted at the Boeing hot nozzle facility on the C8A Buffalo noise suppressor nozzle. Various methods to remove a nozzle-associated 2000-Hz tone are evaluated. Results of testing this rectangular-array lobed nozzle for propulsion performance and acoustic directivity are reported. Recommendations for future nozzle modifications and further testing are included. Appendix A contains the test plan. Appendix B presents the test log. Appendix C contains plots of the one-third octave sound pressure levels recorded during the test. Appendix D describes the acoustic data recording and reduction systems. The performance data is tabulated in Appendix E.

Photovoltaic tests and applications project

NASA Technical Reports Server (NTRS)

1978-01-01

The activities and accomplishments of the Photovoltaic Tests and Applications Project during the period April 1976 through June 1977 are summarized. Results of efforts to identify potential near-term photovoltaic applications and users are discussed, including the outcome of an extensive survey of Federal government agencies. The status of application experiments is presented. Various general engineering efforts are reported, including the design and construction of a photovoltaic Systems Test Facility. Efforts to develop a high efficiency 10 kVA self-commutated inverter and controller specifically designed for photovoltaic systems are also discussed. The results of a wide variety of activities in the area of photovoltaic measurements and standards are related. Documents generated by the Project during the reporting period are listed in an Appendix.

Operational overview of NASA GTE/CITE 1 airborne instrument intercomparisons - Carbon monoxide, nitric oxide, and hydroxyl instrumentation. [Global Tropospheric Experiment/Chemical Instrumentation Test and Evaluation

NASA Technical Reports Server (NTRS)

Beck, Sherwin M.; Bendura, Richard J.; Mcdougal, David S.; Hoell, James M., Jr.; Gregory, Gerald L.; Sachse, Glen W.; Hill, Gerald F.; Curfman, Howard J., Jr.; Torres, Arnold L.; Condon, Estelle P.

1987-01-01

An overview of the airborne intercomparisons of CO, NO, and OH instrumentation is presented in this first paper of the series on the NASA Global Tropospheric Experiment/Chemical Instrumentation Test and Evaluation (GTE/CITE 1). This paper provides the reader with background information about several important characteristics of the project. These include the overall objectives and approach, the measurements taken, the intercomparison protocol, aircraft platform, profiles of each aircraft flight, and the participants. A synopsis of the overall results of the CO, NO, and OH instrument intercomparisons is also included. Companion papers discuss the detailed results of the CO and NO intercomparison tests as well as pertinent scientific findings.

Radiation hardness of Efratom M-100 rubidium frequency standard

NASA Technical Reports Server (NTRS)

English, T. C.; Vorwerk, H.; Rudie, N. J.

1983-01-01

The effects of nuclear radiation on rubidium gas cell frequency standards and components are presented, including the results of recent tests where a continuously operating rubidium frequency standard (Effratom, Model M-100) was subjected to simultaneous neutron/gamma radiation. At the highest neutron fluence 7.5 10 to the 12th power n/sq cm and total dose 11 krad(Si) tested, the unit operated satisfactorily; the total frequency change over the 2 1/2 hour test period due to all causes, including repeated retraction from and insertion into the reactor, was less than 1 x 10 to the -10th power. The effects of combined neutron/gamma radiation on rubidium frequency standard physics package components were also studied, and the results are presented.

Spacesuit Portable Life Support System Breadboard (PLSS 1.0) Development and Test Results

NASA Technical Reports Server (NTRS)

Vogel, Matt R.; Watts, Carly

2011-01-01

A multi-year effort has been carried out at NASA-JSC to develop an advanced Extravehicular Activity (EVA) PLSS design intended to further the current state of the art by increasing operational flexibility, reducing consumables, and increasing robustness. Previous efforts have focused on modeling and analyzing the advanced PLSS architecture, as well as developing key enabling technologies. Like the current International Space Station (ISS) Extravehicular Mobility Unit (EMU) PLSS, the advanced PLSS comprises of three subsystems required to sustain the crew during EVA including the Thermal, Ventilation, and Oxygen Subsystems. This multi-year effort has culminated in the construction and operation of PLSS 1.0, a test rig that simulates full functionality of the advanced PLSS design. PLSS 1.0 integrates commercial off the shelf hardware with prototype technology development components, including the primary and secondary oxygen regulators, ventilation loop fan, Rapid Cycle Amine (RCA) swingbed, and Spacesuit Water Membrane Evaporator (SWME). Testing accumulated 239 hours over 45 days, while executing 172 test points. Specific PLSS 1.0 test objectives assessed during this testing include: confirming key individual components perform in a system level test as they have performed during component level testing; identifying unexpected system-level interactions; operating PLSS 1.0 in nominal steady-state EVA modes to baseline subsystem performance with respect to metabolic rate, ventilation loop pressure and flow rate, and environmental conditions; simulating nominal transient EVA operational scenarios; simulating contingency EVA operational scenarios; and further evaluating individual technology development components. Successful testing of the PLSS 1.0 provided a large database of test results that characterize system level and component performance. With the exception of several minor anomalies, the PLSS 1.0 test rig performed as expected; furthermore, many system responses trended in accordance with pre-test predictions.

Mechanisms flown on LDEF

NASA Technical Reports Server (NTRS)

Dursch, Harry; Spear, Steve

1992-01-01

A wide variety of mechanisms were flown on the Long Duration Exposure Facility (LDEF). These include canisters, valves, gears, drive train assemblies, and motors. This report will provide the status of the Systems SIG effort into documenting, integrating, and developing 'lessons learned' for the variety of mechanisms flown on the LDEF. Results will include both testing data developed by the various experimenters and data acquired by testing of hardware at Boeing.

VETA-I x ray test analysis

NASA Technical Reports Server (NTRS)

Brissenden, R. J. V.; Chartas, G.; Freeman, M. D.; Hughes, J. P.; Kellogg, E. M.; Podgorski, W. A.; Schwartz, D. A.; Zhao, P.

1992-01-01

This interim report presents some definitive results from our analysis of the VETA-I x-ray testing data. It also provides a description of the hardware and software used in the conduct of the VETA-I x-ray test program performed at the MSFC x-ray Calibration Facility (XRCF). These test results also serve to supply data and information to include in the TRW final report required by DPD 692, DR XC04. To provide an authoritative compendium of results, we have taken nine papers as published in the SPIE Symposium, 'Grazing Incidence X-ray/EUV Optics for Astronomy and Projection Lithography' and have reproduced them as the content of this report.

Monomethylhydrazine versus hydrazine fuels - Test results using a 100 pound thrust bipropellant rocket engine

NASA Technical Reports Server (NTRS)

Smith, J. A.; Stechman, R. C.

1981-01-01

A test program was performed to evaluate hydrazine (N2H4) as a fuel for a 445 Newton (100 lbf) thrust bipropellant rocket engine. Results of testing with an identical thruster utilizing monomethylhydrazine (MMH) are included for comparison. Engine performance with hydrazine fuel was essentially identical to that experienced with monomethylhydrazine although higher combustor wall temperatures (approximately 400 F) were obtained with hydrazine. Results are presented which indicate that hydrazine as a fuel is compatible with Marquardt bipropellant rocket engines which use monomethylhydrazine as a baseline fuel.

Interrelationship of mechanical and corrosion-mechanical characteristics of type 12KhN4MF steel

DOE Office of Scientific and Technical Information (OSTI.GOV)

Voronin, V.P.; Goncharov, A.F.; Maslov, V.A.

1985-11-01

Investigations presented include a comparative evaluation of the corrosionmechanical characteristics of specimens of high-strength chrome-nickelmolybdenum steel taking into consideration the different methods of melting of the original metal. A comparison of the corrosion-mechanical test results obtained with the results of acceptance tests are presented. A study of the fracture surfaces and the specimen material with the use of fractographic, macroscopic, and microscopic analyses is given. The systematization of the corrosion-mechanical test results with the use of methods of mathematical statistics are presented.

A study of space shuttle structural integrity test and assessment. Part 1

NASA Technical Reports Server (NTRS)

Anderson, R. E.; Poe, R. G.

1972-01-01

The ultrasonics technique for assessing the structural integrity of the primary surface of the space shuttle vehicles is discussed and evaluated. Analysis was made of transducers, transducer coupling test structure fabrication, flaws, and ultrasonic testing. Graphs of microphone response curves from the initial noise tests, accelerometer response curves from the final noise tests, and microphone curves from the final noise tests are included along with a glossary, bibliography, and results.

Automotive Stirling Engine Development Program

NASA Technical Reports Server (NTRS)

Nightingale, N.; Richey, A.; Farrell, R.; Riecke, G.; Ernst, W.; Howarth, R.; Cronin, M.; Simetkosky, M.; Smith, G.; Meacher, J.

1985-01-01

Development test activities on Mod I engines directed toward evaluating technologies for potential inclusion in the Mod II engine are summarized. Activities covered include: test of a 12-tube combustion gas recirculation combustor; manufacture and flow-distribution test of a two-manifold annular heater head; piston rod/piston base joint; single-solid piston rings; and a digital air/fuel concept. Also summarized are results of a formal assessment of candidate technologies for the Mod II engine, and preliminary design work for the Mod II. The overall program philosophy weight is outlined, and data and test results are presented.

Skylab parasol material evaluation

NASA Technical Reports Server (NTRS)

Jacobs, S.

1975-01-01

Results of experimental work to evaluate the degradation rate of a parasol that was used as a means of alleviating thermal problems encountered soon after the launch of the Skylab 1 space vehicle are presented. Material selection criteria are discussed; the material chosen is described, and results of tests performed after environmental exposure at five facilities are given. The facilities used for exposure to ultraviolet radiation/thermal-vacuum environments and the equipment used for testing physical properties before and after exposure are described. Comparisons of ground test and flight test data are included.

Dataset for Testing Contamination Source Identification Methods for Water Distribution Networks

EPA Pesticide Factsheets

This dataset includes the results of a simulation study using the source inversion techniques available in the Water Security Toolkit. The data was created to test the different techniques for accuracy, specificity, false positive rate, and false negative rate. The tests examined different parameters including measurement error, modeling error, injection characteristics, time horizon, network size, and sensor placement. The water distribution system network models that were used in the study are also included in the dataset. This dataset is associated with the following publication:Seth, A., K. Klise, J. Siirola, T. Haxton , and C. Laird. Testing Contamination Source Identification Methods for Water Distribution Networks. Journal of Environmental Division, Proceedings of American Society of Civil Engineers. American Society of Civil Engineers (ASCE), Reston, VA, USA, ., (2016).

Solar electric propulsion thrust subsystem development

NASA Technical Reports Server (NTRS)

Masek, T. D.

1973-01-01

The Solar Electric Propulsion System developed under this program was designed to demonstrate all the thrust subsystem functions needed on an unmanned planetary vehicle. The demonstration included operation of the basic elements, power matching input and output voltage regulation, three-axis thrust vector control, subsystem automatic control including failure detection and correction capability (using a PDP-11 computer), operation of critical elements in thermal-vacuum-, zero-gravity-type propellant storage, and data outputs from all subsystem elements. The subsystem elements, functions, unique features, and test setup are described. General features and capabilities of the test-support data system are also presented. The test program culminated in a 1500-h computer-controlled, system-functional demonstration. This included simultaneous operation of two thruster/power conditioner sets. The results of this testing phase satisfied all the program goals.

Pregnant patients' risk perception of prenatal test results with uncertain fetal clinical significance: ultrasound versus advanced genetic testing.

PubMed

Richards, Elliott G; Sangi-Haghpeykar, Haleh; McGuire, Amy L; Van den Veyver, Ignatia B; Fruhman, Gary

2015-12-01

A common concern of utilizing prenatal advanced genetic testing is that a result of uncertain clinical significance will increase patient anxiety. However, prenatal ultrasound may also yield findings of uncertain significance, such as 'soft markers' for fetal aneuploidy, or findings with variable prognosis, such as mild ventriculomegaly. In this study we compared risk perception following uncertain test results from each modality. A single survey with repeated measures design was administered to 133 pregnant women. It included 'intolerance of uncertainty' questions, two hypothetical scenarios involving prenatal ultrasound or advanced genetic testing, and response questions. The primary outcome was risk perception score. Risk perception did not vary significantly between ultrasound and genetic scenarios (p = 0.17). The genetic scenario scored a higher accuracy (p = 0.04) but lower sense of empowerment (p = 0.01). Furthermore, patients were more likely to seek additional testing after an ultrasound than after genetic testing (p = 0.05). There were no differences in other secondary outcomes including perception of life-altering consequences and hypothetical worry, anxiety, confusion, or medical care decisions. Our data suggest that uncertain findings on prenatal genetic testing do not elicit a higher perception of risk or anxiety when compared to ultrasound findings of comparable uncertainty. © 2015 John Wiley & Sons, Ltd. © 2015 John Wiley & Sons, Ltd.

AGR-1 Thermocouple Data Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jeff Einerson

2012-05-01

This report documents an effort to analyze measured and simulated data obtained in the Advanced Gas Reactor (AGR) fuel irradiation test program conducted in the INL's Advanced Test Reactor (ATR) to support the Next Generation Nuclear Plant (NGNP) R&D program. The work follows up on a previous study (Pham and Einerson, 2010), in which statistical analysis methods were applied for AGR-1 thermocouple data qualification. The present work exercises the idea that, while recognizing uncertainties inherent in physics and thermal simulations of the AGR-1 test, results of the numerical simulations can be used in combination with the statistical analysis methods tomore » further improve qualification of measured data. Additionally, the combined analysis of measured and simulation data can generate insights about simulation model uncertainty that can be useful for model improvement. This report also describes an experimental control procedure to maintain fuel target temperature in the future AGR tests using regression relationships that include simulation results. The report is organized into four chapters. Chapter 1 introduces the AGR Fuel Development and Qualification program, AGR-1 test configuration and test procedure, overview of AGR-1 measured data, and overview of physics and thermal simulation, including modeling assumptions and uncertainties. A brief summary of statistical analysis methods developed in (Pham and Einerson 2010) for AGR-1 measured data qualification within NGNP Data Management and Analysis System (NDMAS) is also included for completeness. Chapters 2-3 describe and discuss cases, in which the combined use of experimental and simulation data is realized. A set of issues associated with measurement and modeling uncertainties resulted from the combined analysis are identified. This includes demonstration that such a combined analysis led to important insights for reducing uncertainty in presentation of AGR-1 measured data (Chapter 2) and interpretation of simulation results (Chapter 3). The statistics-based simulation-aided experimental control procedure described for the future AGR tests is developed and demonstrated in Chapter 4. The procedure for controlling the target fuel temperature (capsule peak or average) is based on regression functions of thermocouple readings and other relevant parameters and accounting for possible changes in both physical and thermal conditions and in instrument performance.« less