The Effects of Chlordiazepoxide and d-Amphetamine during a Three-Component Multiple Schedule
Romanowich, Paul; Lamb, R. J.
2013-01-01
Multiple schedules have been used in behavioral pharmacology research to show that a drug’s effect on behavior can be a function of the schedule of reinforcement that supports that behavior. However, less research has examined whether the context of the schedule of reinforcement in a multiple schedule can change the drug’s effect on behavior. We examined the effects of acute chlordiazepoxide and d-amphetamine injections on the behavior of two groups of pigeons trained on a three-component multiple schedule with identical schedules of reinforcement in the first and last components. For one group of pigeons reinforcement was unavailable during the middle component (decreased-middle-component). For the second group reinforcement rate was higher during the middle component than during the first or third components (increased-middle-component). In the decreased-middle-component group, chlordiazepoxide (3.2-32 mg/kg) decreased third-component response rates less than it decreased responding in the first component. Conversely, in the increased-middle-component group, chlordiazepoxide (3.2-10 mg/kg) decreased third-component response rates more than in the first component. In both groups, d-amphetamine did not differentially affect response rates across components. These results are consistent with previous research showing that drugs can differentially affect responding to two different schedules of reinforcement during the same session, and suggest that pharmacological preparations may be helpful in elucidating the mechanisms that control multiple schedule interactions. PMID:23633164
Hoffmeister, F
1980-01-01
Rhesus monkeys were trained to complete three multiple schedules. The schedules consisted of three components: a fixed interval (component 1), a variable interval (component 2), and a fixed ratio (component 3). During components 1 and 2, pressing lever 1 was always reinforced by food delivery. During component 3, pressing lever 2 resulted in either food delivery or intravenous infusions of saline solution, solutions of cocaine, of d-amphetamine, of phenmetrazine, or fenetylline. In schedule I, animals were presented with all three components independent of key-pressing behavior during components 1 and 2. In schedule II the availability of component 2 was dependent on completion of component 1. Component 3 was made available only on completion of component 2. Noncompletion of components 1 or 2 resulted in time-out of 15 and 10 min, respectively. Schedule III was identical with schedule II, except that in schedule III the completion of components was indicated only by a change in the lever lights. The influence of self-administered drugs on behavior in all three components was evaluated. Self-administration of psychomotor stimulants impaired the performance of animals and delayed completion of components 1 and 2 of schedules I, II, and III. The effects on behavior were similar with low drug intake in schedule III, moderate intake in schedule II, and high drug intake in schedule I. These effects were strong with self-administration of phenmetrazine, moderate with self-administration of cocaine and d-amphetamine, and weak with self-administration of fenetylline.
ERIC Educational Resources Information Center
Williams, Dean C.; Saunders, Kathryn J.; Perone, Michael
2011-01-01
We conducted three experiments to reproduce and extend Perone and Courtney's (1992) study of pausing at the beginning of fixed-ratio schedules. In a multiple schedule with unequal amounts of food across two components, they found that pigeons paused longest in the component associated with the smaller amount of food (the lean component), but only…
Morrison, Heather; Roscoe, Eileen M; Atwell, Amy
2011-01-01
We evaluated antecedent exercise for treating the automatically reinforced problem behavior of 4 individuals with autism. We conducted preference assessments to identify leisure and exercise items that were associated with high levels of engagement and low levels of problem behavior. Next, we conducted three 3-component multiple-schedule sequences: an antecedent-exercise test sequence, a noncontingent leisure-item control sequence, and a social-interaction control sequence. Within each sequence, we used a 3-component multiple schedule to evaluate preintervention, intervention, and postintervention effects. Problem behavior decreased during the postintervention component relative to the preintervention component for 3 of the 4 participants during the exercise-item assessment; however, the effects could not be attributed solely to exercise for 1 of these participants. PMID:21941383
An Evaluation of a Three-Component Multiple Schedule to Indicate Attention Availability
ERIC Educational Resources Information Center
Nava, Maria J.; Vargo, Kristina K.; Babino, Misti M.
2016-01-01
Students may engage in high rates of social approach responses at inappropriate times throughout the school day. One intervention that has been used to teach students appropriate and inappropriate times to access attention is a multiple schedule of reinforcement. In this study, we evaluated the efficacy of a multiple schedule that indicated when…
Response-reinforcer dependency and resistance to change.
Cançado, Carlos R X; Abreu-Rodrigues, Josele; Aló, Raquel Moreira; Hauck, Flávia; Doughty, Adam H
2018-01-01
The effects of the response-reinforcer dependency on resistance to change were studied in three experiments with rats. In Experiment 1, lever pressing produced reinforcers at similar rates after variable interreinforcer intervals in each component of a two-component multiple schedule. Across conditions, in the fixed component, all reinforcers were response-dependent; in the alternative component, the percentage of response-dependent reinforcers was 100, 50 (i.e., 50% response-dependent and 50% response-independent) or 10% (i.e., 10% response-dependent and 90% response-independent). Resistance to extinction was greater in the alternative than in the fixed component when the dependency in the former was 10%, but was similar between components when this dependency was 100 or 50%. In Experiment 2, a three-component multiple schedule was used. The dependency was 100% in one component and 10% in the other two. The 10% components differed on how reinforcers were programmed. In one component, as in Experiment 1, a reinforcer had to be collected before the scheduling of other response-dependent or independent reinforcers. In the other component, response-dependent and -independent reinforcers were programmed by superimposing a variable-time schedule on an independent variable-interval schedule. Regardless of the procedure used to program the dependency, resistance to extinction was greater in the 10% components than in the 100% component. These results were replicated in Experiment 3 in which, instead of extinction, VT schedules replaced the baseline schedules in each multiple-schedule component during the test. We argue that the relative change in dependency from Baseline to Test, which is greater when baseline dependencies are high rather than low, could account for the differential resistance to change in the present experiments. The inconsistencies in results across the present and previous experiments suggest that the effects of dependency on resistance to change are not well understood. Additional systematic analyses are important to further understand the effects of the response-reinforcer relation on resistance to change and to the development of a more comprehensive theory of behavioral persistence. © 2017 Society for the Experimental Analysis of Behavior.
Williams, Dean C; Saunders, Kathryn J; Perone, Michael
2011-01-01
We conducted three experiments to reproduce and extend Perone and Courtney's (1992) study of pausing at the beginning of fixed-ratio schedules. In a multiple schedule with unequal amounts of food across two components, they found that pigeons paused longest in the component associated with the smaller amount of food (the lean component), but only when it was preceded by the rich component. In our studies, adults with mild intellectual disabilities responded on a touch-sensitive computer monitor to produce money. In Experiment 1, the multiple-schedule components differed in both response requirement and reinforcer magnitude (i.e., the rich component required fewer responses and produced more money than the lean component). Effects shown with pigeons were reproduced in all 7 participants. In Experiment 2, we removed the stimuli that signaled the two schedule components, and participants' extended pausing was eliminated. In Experiment 3, to assess sensitivity to reinforcer magnitude versus fixed-ratio size, we presented conditions with equal ratio sizes but disparate magnitudes and conditions with equal magnitudes but disparate ratio sizes. Sensitivity to these manipulations was idiosyncratic. The present experiments obtained schedule control in verbally competent human participants and, despite procedural differences, we reproduced findings with animal participants. We showed that pausing is jointly determined by past conditions of reinforcement and stimuli correlated with upcoming conditions. PMID:21541121
Key-peck durations under behavioral contrast and differential reinforcement
Whipple, William R.; Fantino, Edmund
1980-01-01
Pigeons were maintained on a multiple schedule in which both components were variable-interval one-minute schedules. When they were switched to a condition in which one component was extinction, behavioral contrast was observed. The median durations of the key pecks in the unchanged component did not decrease in size. The results are incompatible with a theory of behavioral contrast which considers the added pecks to be short-duration responses. In a second experiment, pigeons were required to emit short-duration key pecks in one component of a multiple schedule, and long-duration pecks in the other. Two of three pigeons learned to emit responses appropriate to the requirements of the component in effect, suggesting that the duration of the key-peck response is sensitive to differential reinforcement. PMID:16812185
Signals, resistance to change, and conditioned reinforcement in a multiple schedule.
Bell, Matthew C; Gomez, Belen E; Kessler, Kira
2008-06-01
The effect of signals on resistance to change was evaluated using pigeons responding on a three-component multiple schedule. Each component contained a variable-interval initial link followed by a fixed-time terminal link. One component was an unsignaled-delay schedule, and two were equivalent signaled-delay schedules. After baseline training, resistance to change was assessed through (a) extinction and (b) adding free food to the intercomponent interval. During these tests, the signal stimulus from one of the signaled-delay components (SIG-T) was replaced with the initial-link stimulus from that component, converting it to an unsignaled-delay schedule. That signal stimulus was added to the delay period of the unsignaled-delay component (UNS), converting it to a signaled-delay schedule. The remaining signaled component remained unchanged (SIG-C). Resistance-to-change tests showed removing the signal had a minimal effect on resistance to change in the SIG-T component compared to the unchanged SIG-C component except for one block during free-food testing. Adding the signal to the UNS component significantly increased response rates suggesting that component had low response strength. Interestingly, the direction of the effect was in the opposite direction from what is typically observed. Results are consistent with the conclusion that the signal functioned as a conditioned reinforcer and inconsistent with a generalization-decrement explanation.
Behavioral regulation of gravity - Schedule effects under escape-avoidance procedures
NASA Technical Reports Server (NTRS)
Clark, F. C.; Lange, K. O.; Belleville, R. E.
1973-01-01
Squirrel monkeys were restrained in a centrifuge capsule and trained to escape and avoid increases in artificial gravity. During escape-avoidance, lever responses reduced centrifugally simulated gravity or postponed scheduled increases. The effect of variation in the interval of postponement (equal to the duration of decrease produced by escape responses) was studied under a multiple schedule of four components. Three components were gravity escape-avoidance with postponement times of 20, 40, and 60 sec. The fourth component was extinction. Each component was associated with a different auditory stimulus. Rate of responding decreased with increasing postponement time and higher mean g-levels occurred at shorter intervals of postponement. Effects of the schedule parameter on response rate and mean g-level were similar to effects of the schedule on free-operant avoidance and on titration behavior maintained by shock.
Conditioned Reinforcement Value and Resistance to Change
ERIC Educational Resources Information Center
Shahan, Timothy A.; Podlesnik, Christopher A.
2008-01-01
Three experiments examined the effects of conditioned reinforcement value and primary reinforcement rate on resistance to change using a multiple schedule of observing-response procedures with pigeons. In the absence of observing responses in both components, unsignaled periods of variable-interval (VI) schedule food reinforcement alternated with…
Behavioral regulation of gravity: schedule effects under escape-avoidance procedures1
Clark, Fogle C.; Lange, Karl O.; Belleville, Richard E.
1973-01-01
Squirrel monkeys were restrained in a centrifuge capsule and trained to escape and avoid increases in artificial gravity. During escape-avoidance, lever responses reduced centrifugally simulated gravity or postponed scheduled increases. The effect of variation in the interval of postponement (equal to the duration of decrease produced by escape responses) was studied under a multiple schedule of four components. Three components were gravity escape-avoidance with postponement times of 20, 40, and 60 sec. The fourth component was extinction. Each component was associated with a different auditory stimulus. Rate of responding decreased with increasing postponement time and higher mean g-levels occurred at shorter intervals of postponement. Effects of the schedule parameter on response rate and mean g-level were similar to effects of the schedule on free-operant avoidance and on titration behavior maintained by shock. ImagesFig. 1. PMID:4202386
Effects of conditioned reinforcement frequency in an intermittent free-feeding situation, 12
Zimmerman, Joseph; Hanford, Peter V.; Brown, Wyman
1967-01-01
Key-pecking intermittently produced a set of brief exteroceptive stimulus changes under two-component multiple schedules of conditioned reinforcement. Throughout the study, free access to grain was concurrently provided on an intermittent basis via a variable-interval tape. Free food presentations scheduled by the tape were delivered if no peck had been emitted for 6 sec, and the brief stimulus changes produced by responding under the multiple schedules were those which accompanied food presentation. The second component of each multiple schedule was always associated with a 1-min, variable-interval schedule of conditioned reinforcement. The schedule associated with the first component was systematically varied and conditioned reinforcement was either absent (extinction) or programmed on a 1-, 3-, 6-, or 12-min variable-interval schedule. Under these conditions, rate of responding in the manipulated component decreased monotonically with a decrease in the frequency of conditioned reinforcement. In addition, contrast effects were often obtained in the constant, second component. These results are similar to those obtained with similar multiple schedules of primary reinforcement. PMID:6033554
Response Strength in Extreme Multiple Schedules
ERIC Educational Resources Information Center
McLean, Anthony P.; Grace, Randolph C.; Nevin, John A.
2012-01-01
Four pigeons were trained in a series of two-component multiple schedules. Reinforcers were scheduled with random-interval schedules. The ratio of arranged reinforcer rates in the two components was varied over 4 log units, a much wider range than previously studied. When performance appeared stable, prefeeding tests were conducted to assess…
BEHAVIORAL MOMENTUM AND ACCUMULATION OF MASS IN MULTIPLE SCHEDULES
Craig, Andrew R.; Cunningham, Paul J.; Shahan, Timothy A.
2015-01-01
Behavioral momentum theory suggests that the relation between a discriminative-stimulus situation and reinforcers obtained in that context (i.e., the Pavlovian stimulus–reinforcer relation) governs persistence of operant behavior. Within the theory, a mass-like aspect of behavior has been shown to be a power function of predisruption reinforcement rates. Previous investigations of resistance to change in multiple schedules, however, have been restricted to examining response persistence following protracted periods of stability in reinforcer rates within a discriminative situation. Thus, it is unclear how long a stimulus–reinforcer relation must be in effect prior to disruption in order to affect resistance to change. The present experiment examined resistance to change of pigeon’s key pecking following baseline conditions where reinforcer rates that were correlated with discriminative-stimulus situations changed. Across conditions, one multiple-schedule component arranged either relatively higher rates or lower rates of variable-interval food delivery, while the other component arranged the opposite rate. These schedules alternated between multiple-schedule components across blocks of sessions such that reinforcer rates in the components were held constant for 20, 5, 3, 2, or 1 session(s) between alternations. Resistance to extinction was higher in the component that most recently was associated with higher rates of food delivery in all conditions except when schedules alternated daily or every other day. These data suggest that resistance to change in multiple schedules is related to recently experienced reinforcer rates but only when multiple-schedule components are associated with specific reinforcer rates for several sessions. PMID:25787824
Belke, Terry W; Pierce, W David
2016-12-01
Rats responded on a multiple variable-ratio (VR) 10 VR 10 schedule of reinforcement in which lever pressing was reinforced by the opportunity to run in a wheel for 30s in both the changed (manipulated) and unchanged components. To generate positive contrast, the schedule of reinforcement in the changed component was shifted to extinction; to generate negative contrast, the schedule was shifted to VR 3. With the shift to extinction in the changed component, wheel-running and local lever-pressing rates increased in the unchanged component, a result supporting positive contrast; however, the shift to a VR 3 schedule in the changed component showed no evidence of negative contrast in the unaltered setting, only wheel running decreased in the unchanged component. Changes in wheel-running rates across components were consistent in showing a compensation effect, depending on whether the schedule manipulation increased or decreased opportunities for wheel running in the changed component. These findings are the first to demonstrate positive behavioral contrast on a multiple schedule with wheel running as reinforcement in both components. Copyright © 2016 Elsevier B.V. All rights reserved.
Influences on cocaine tolerance assessed under a multiple conjunctive schedule of reinforcement.
Yoon, Jin Ho; Branch, Marc N
2009-11-01
Under multiple schedules of reinforcement, previous research has generally observed tolerance to the rate-decreasing effects of cocaine that has been dependent on schedule-parameter size in the context of fixed-ratio (FR) schedules, but not under the context of fixed-interval (FI) schedules of reinforcement. The current experiment examined the effects of cocaine on key-pecking responses of White Carneau pigeons maintained under a three-component multiple conjunctive FI (10 s, 30 s, & 120 s) FR (5 responses) schedule of food presentation. Dose-effect curves representing the effects of presession cocaine on responding were assessed in the context of (1) acute administration of cocaine (2) chronic administration of cocaine and (3) daily administration of saline. Chronic administration of cocaine generally resulted in tolerance to the response-rate decreasing effects of cocaine, and that tolerance was generally independent of relative FI value, as measured by changes in ED50 values. Daily administration of saline decreased ED50 values to those observed when cocaine was administered acutely. The results show that adding a FR requirement to FI schedules is not sufficient to produce schedule-parameter-specific tolerance. Tolerance to cocaine was generally independent of FI-parameter under the present conjunctive schedules, indicating that a ratio requirement, per se, is not sufficient for tolerance to be dependent on FI parameter.
Independence of Terminal-Link Entry Rate and Immediacy in Concurrent Chains
ERIC Educational Resources Information Center
Berg, Mark E.; Grace, Randolph C.
2004-01-01
In Phase 1, 4 pigeons were trained on a three-component multiple concurrent-chains procedure in which components differed only in terms of relative terminal-link entry rate. The terminal links were variable-interval schedules and were varied across four conditions to produce immediacy ratios of 4:1, 1:4, 2:1, and 1:2. Relative terminal-link entry…
Landa, Robin; Hanley, Gregory P
2016-06-01
Using procedures similar to those of Tiger, Hanley, and Heal (2006), we compared two multiple-schedule variations (S+/S- and S+ only) to treat high-rate requests for edible items in the Picture Exchange Communication System (PECS). Two individuals with autism participated, after they showed persistent requests for edible items after PECS training. Stimulus control was achieved only with the multiple schedule that involved presentation of a discriminative stimulus during reinforcement components and its removal during extinction components (S+ only). Discriminated requests were maintained for the 1 participant who experienced schedule thinning. © 2016 Society for the Experimental Analysis of Behavior.
Pietras, Cynthia J; Brandt, Andrew E; Searcy, Gabriel D
2010-01-01
An experiment with adult humans investigated the effects of response-contingent money loss (response-cost punishment) on monetary-reinforced responding. A yoked-control procedure was used to separate the effects on responding of the response-cost contingency from the effects of reduced reinforcement density. Eight adults pressed buttons for money on a three-component multiple reinforcement schedule. During baseline, responding in all components produced money gains according to a random-interval 20-s schedule. During punishment conditions, responding during the punishment component conjointly produced money losses according to a random-interval schedule. The value of the response-cost schedule was manipulated across conditions to systematically evaluate the effects on responding of response-cost frequency. Participants were assigned to one of two yoked-control conditions. For participants in the Yoked Punishment group, during punishment conditions money losses were delivered in the yoked component response independently at the same intervals that money losses were produced in the punishment component. For participants in the Yoked Reinforcement group, responding in the yoked component produced the same net earnings as produced in the punishment component. In 6 of 8 participants, contingent response cost selectively decreased response rates in the punishment component and the magnitude of the decrease was directly related to the punishment schedule value. Under punishment conditions, for participants in the Yoked Punishment group response rates in the yoked component also decreased, but the decrease was less than that observed in the punishment component, whereas for participants in the Yoked Reinforcement group response rates in the yoked component remained similar to rates in the no-punishment component. These results provide further evidence that contingent response cost functions similarly to noxious punishers in that it appears to suppress responding apart from its effects on reinforcement density. PMID:20676265
ERIC Educational Resources Information Center
Lanovaz, Marc J.; Fletcher, Sarah E.; Rapp, John T.
2009-01-01
We used a three-component multiple-schedule with a brief reversal design to evaluate the effects of structurally unmatched and matched stimuli on immediate and subsequent vocal stereotypy that was displayed by three children with autism spectrum disorders. For 2 of the 3 participants, access to matched stimuli, unmatched stimuli, and music…
Contrast and autoshaping in multiple schedules varying reinforcer rate and duration.
Hamilton, B E; Silberberg, A
1978-07-01
Thirteen master pigeons were exposed to multiple schedules in which reinforcement frequency (Experiment I) or duration (Experiment II) was varied. In Phases 1 and 3 of Experiment I, the values of the first and second components' random-interval schedules were 33 and 99 seconds, respectively. In Phase 2, these values were 99 seconds for both components. In Experiment II, a random-interval 33-second schedule was associated with each component. During Phases 1 and 3, the first and second components had hopper durations of 7.5 and 2.5 seconds respectively. During Phase 2, both components' hopper durations were 2.5 seconds. In each experiment, positive contrast obtained for about half the master subjects. The rest showed a rate increase in both components (positive induction). Each master subject's key colors and reinforcers were synchronously presented on a response-independent basis to a yoked control. Richer component key-pecking occurred during each experiment's Phases 1 and 3 among half these subjects. However, none responded during the contrast condition (unchanged component of each experiment's Phase 2). From this it is inferred that autoshaping did not contribute to the contrast and induction findings among master birds. Little evidence of local contrast (highest rate at beginning of richer component) was found in any subject. These data show that (a) contrast can occur independently from autoshaping, (b) contrast assays during equal-valued components may produce induction, (c) local contrast in multiple schedules often does not occur, and (d) differential hopper durations can produce autoshaping and contrast.
Campos, Claudia; Leon, Yanerys; Sleiman, Andressa; Urcuyo, Beatriz
2017-03-01
One potential limitation of functional communication training (FCT) is that after the functional communication response (FCR) is taught, the response may be emitted at high rates or inappropriate times. Thus, schedule thinning is often necessary. Previous research has demonstrated that multiple schedules can facilitate schedule thinning by establishing discriminative control of the communication response while maintaining low rates of problem behavior. To date, most applied research evaluating the clinical utility of multiple schedules has done so in the context of behavior maintained by positive reinforcement (e.g., attention or tangible items). This study examined the use of a multiple schedule with alternating Fixed Ratio (FR 1)/extinction (EXT) components for two individuals with developmental disabilities who emitted escape-maintained problem behavior. Although problem behavior remained low during all FCT and multiple schedule phases, the use of the multiple schedule alone did not result in discriminated manding.
The Reinforcing Effects of Houselight Illumination during Chained Schedules of Food Presentation
ERIC Educational Resources Information Center
Allen, Ron; Kupfer, Jeff; Malagodi, E. F.
2008-01-01
Pigeons' keypecking was maintained under two- and three-component chained schedules of food presentation. The component schedules were all fixed-interval schedules of either 1- or 2-min duration. Across conditions the presence of houselight illumination within each component schedule was manipulated. For each pigeon, first-component response rates…
McLean, A P; Blampied, N M
1995-01-01
Behavioral momentum theory relates resistance to change of responding in a multiple-schedule component to the total reinforcement obtained in that component, regardless of how the reinforcers are produced. Four pigeons responded in a series of multiple-schedule conditions in which a variable-interval 40-s schedule arranged reinforcers for pecking in one component and a variable-interval 360-s schedule arranged them in the other. In addition, responses on a second key were reinforced according to variable-interval schedules that were equal in the two components. In different parts of the experiment, responding was disrupted by changing the rate of reinforcement on the second key or by delivering response-independent food during a blackout separating the two components. Consistent with momentum theory, responding on the first key in Part 1 changed more in the component with the lower reinforcement total when it was disrupted by changes in the rate of reinforcement on the second key. However, responding on the second key changed more in the component with the higher reinforcement total. In Parts 2 and 3, responding was disrupted with free food presented during intercomponent blackouts, with extinction (Part 2) or variable-interval 80-s reinforcement (Part 3) arranged on the second key. Here, resistance to change was greater for the component with greater overall reinforcement. Failures of momentum theory to predict short-term differences in resistance to change occurred with disruptors that caused greater change between steady states for the richer component. Consistency of effects across disruptors may yet be found if short-term effects of disruptors are assessed relative to the extent of change observed after prolonged exposure.
Contrast and autoshaping in multiple schedules varying reinforcer rate and duration
Hamilton, Bruce E.; Silberberg, Alan
1978-01-01
Thirteen master pigeons were exposed to multiple schedules in which reinforcement frequency (Experiment I) or duration (Experiment II) was varied. In Phases 1 and 3 of Experiment I, the values of the first and second components' random-interval schedules were 33 and 99 seconds, respectively. In Phase 2, these values were 99 seconds for both components. In Experiment II, a random-interval 33-second schedule was associated with each component. During Phases 1 and 3, the first and second components had hopper durations of 7.5 and 2.5 seconds respectively. During Phase 2, both components' hopper durations were 2.5 seconds. In each experiment, positive contrast obtained for about half the master subjects. The rest showed a rate increase in both components (positive induction). Each master subject's key colors and reinforcers were synchronously presented on a response-independent basis to a yoked control. Richer component key-pecking occurred during each experiment's Phases 1 and 3 among half these subjects. However, none responded during the contrast condition (unchanged component of each experiment's Phase 2). From this it is inferred that autoshaping did not contribute to the contrast and induction findings among master birds. Little evidence of local contrast (highest rate at beginning of richer component) was found in any subject. These data show that (a) contrast can occur independently from autoshaping, (b) contrast assays during equal-valued components may produce induction, (c) local contrast in multiple schedules often does not occur, and (d) differential hopper durations can produce autoshaping and contrast. PMID:16812081
The role of response force on the persistence and structure of behavior during extinction.
Pinkston, Jonathan W; Foss, Erica K
2018-01-01
Behavior Momentum Theory has emerged as a prominent account of resistance to change in both basic and applied research. Although laboratory studies often define precise, repeatable responses, application research often deals with response classes that may vary widely along a number of dimensions. In general, Behavior Momentum Theory has not addressed how response dimensions impact resistance to change, providing an opportunity to expand the model in new directions. Four rats pressed a force transducer under a multiple variable interval (VI) 60-s VI 60-s schedule of reinforcement. In one component, responses satisfied the schedule only if the response force fell within a "low" force band requirement; responses in the other schedule were required to satisfy a "high" force band. Once responding stabilized, extinction was programmed for three sessions. Then, the procedures were replicated. The results showed that response force came under discriminative control, but force requirements had no impact on resistance to extinction. In a follow-up condition, the schedule was changed to a multiple VI 30-s VI 120-s schedule and the low-force band operated in both components. The results showed that behavior maintained by the VI 30-s schedule was generally more resistant to extinction. A secondary analysis showed that force distributions created under baseline maintained during extinction. Overall, the results suggest that differential response force requirements prevailing in steady state do not affect the course of extinction. © 2018 Society for the Experimental Analysis of Behavior.
Ginsburg, Brett C; Lamb, Richard J
2014-03-01
Varenicline, a nicotinic partial agonist, selectively reduces ethanol (EtOH)- versus sucrose-maintained behavior when tested in separate groups, yet like the indirect agonist fluvoxamine, this selectively inverts when EtOH and food are concurrently available. Here, we extend these findings by examining varenicline and fluvoxamine effects under a multiple concurrent schedule where food and EtOH are concurrently available in different components: Component 1 where the food fixed-ratio was 25 and Component 2 where the food fixed-ratio was 75. The EtOH fixed-ratio was always 5. Food-maintained responding predominated in Component 1, while EtOH-maintained responding predominated in Component 2. In a second experiment, varenicline effects were assessed under a multiple schedule where food, then EtOH, then again food were available in separate 5-minute components with fixed-ratios of 5 for each reinforcement. In the multiple concurrent schedule, varenicline was more potent at reducing food- versus EtOH-maintained responding in both components and reduced EtOH-maintained responding more potently during Component 1 (when food was almost never earned) than in Component 2 (where food was often earned). Fluvoxamine was similarly potent at reducing food- and EtOH-maintained responding. Under the multiple schedule, varenicline, like fluvoxamine, more potently decreases EtOH- versus food maintained responding when only food or EtOH is available in separate components. These results demonstrate that selective effects on drug- versus alternative-maintained behavior depend on the schedule arrangement, and assays in which EtOH or an alternative is the only programmed reinforcement may overestimate the selectivity of treatments to decrease EtOH self-administration. Thus selective effects obtained under one assay may not generalize to another. Better understanding the behavioral mechanisms responsible for these results may help to guide pharmaco-therapeutic development for substance use disorders.
ERIC Educational Resources Information Center
Winsauer, Peter J.; Moerschbaecher, Joseph M.; Roussell, Alison M.
2008-01-01
Six rhesus monkeys responding under a three-component multiple schedule were administered haloperidol to determine its effects on cocaine self-administration and on cocaine's disruptive effects on the repeated acquisition and performance of response chains. In the absence of haloperidol, 0.0032 - 0.032 mg/kg/infusion of cocaine increased response…
A Component Analysis of Schedule Thinning during Functional Communication Training
ERIC Educational Resources Information Center
Betz, Alison M.; Fisher, Wayne W.; Roane, Henry S.; Mintz, Joslyn C.; Owen, Todd M.
2013-01-01
One limitation of functional communication training (FCT) is that individuals may request reinforcement via the functional communication response (FCR) at exceedingly high rates. Multiple schedules with alternating periods of reinforcement and extinction of the FCR combined with gradually lengthening the extinction-component interval can…
NASA Astrophysics Data System (ADS)
Lee, Junghyun; Kim, Heewon; Chung, Hyun; Kim, Haedong; Choi, Sujin; Jung, Okchul; Chung, Daewon; Ko, Kwanghee
2018-04-01
In this paper, we propose a method that uses a genetic algorithm for the dynamic schedule optimization of imaging missions for multiple satellites and ground systems. In particular, the visibility conflicts of communication and mission operation using satellite resources (electric power and onboard memory) are integrated in sequence. Resource consumption and restoration are considered in the optimization process. Image acquisition is an essential part of satellite missions and is performed via a series of subtasks such as command uplink, image capturing, image storing, and image downlink. An objective function for optimization is designed to maximize the usability by considering the following components: user-assigned priority, resource consumption, and image-acquisition time. For the simulation, a series of hypothetical imaging missions are allocated to a multi-satellite control system comprising five satellites and three ground stations having S- and X-band antennas. To demonstrate the performance of the proposed method, simulations are performed via three operation modes: general, commercial, and tactical.
An Enabling Technology for New Planning and Scheduling Paradigms
NASA Technical Reports Server (NTRS)
Jaap, John; Davis, Elizabeth
2004-01-01
The Night Projects Directorate at NASA's Marshall Space Flight Center is developing a new planning and scheduling environment and a new scheduling algorithm to enable a paradigm shift in planning and scheduling concepts. Over the past 33 years Marshall has developed and evolved a paradigm for generating payload timelines for Skylab, Spacelab, various other Shuttle payloads, and the International Space Station. The current paradigm starts by collecting the requirements, called ?ask models," from the scientists and technologists for the tasks that are to be scheduled. Because of shortcomings in the current modeling schema, some requirements are entered as notes. Next, a cadre with knowledge of vehicle and hardware modifies these models to encompass and be compatible with the hardware model; again, notes are added when the modeling schema does not provide a better way to represent the requirements. Finally, the models are modified to be compatible with the scheduling engine. Then the models are submitted to the scheduling engine for automatic scheduling or, when requirements are expressed in notes, the timeline is built manually. A future paradigm would provide a scheduling engine that accepts separate science models and hardware models. The modeling schema would have the capability to represent all the requirements without resorting to notes. Furthermore, the scheduling engine would not require that the models be modified to account for the capabilities (limitations) of the scheduling engine. The enabling technology under development at Marshall has three major components: (1) A new modeling schema allows expressing all the requirements of the tasks without resorting to notes or awkward contrivances. The chosen modeling schema is both maximally expressive and easy to use. It utilizes graphical methods to show hierarchies of task constraints and networks of temporal relationships. (2) A new scheduling algorithm automatically schedules the models without the intervention of a scheduling expert. The algorithm is tuned for the constraint hierarchies and the complex temporal relationships provided by the modeling schema. It has an extensive search algorithm that can exploit timing flexibilities and constraint and relationship options. (3) An innovative architecture allows multiple remote users to simultaneously model science and technology requirements and other users to model vehicle and hardware characteristics. The architecture allows the remote users to submit scheduling requests directly to the scheduling engine and immediately see the results. These three components are integrated so that science and technology experts with no knowledge of the vehicle or hardware subsystems and no knowledge of the internal workings of the scheduling engine have the ability to build and submit scheduling requests and see the results. The immediate feedback will hone the users' modeling skills and ultimately enable them to produce the desired timeline. This paper summarizes the three components of the enabling technology and describes how this technology would make a new paradigm possible.
Resistance to change and frequency of response-dependent stimuli uncorrelated with reinforcement.
Podlesnik, Christopher A; Jimenez-Gomez, Corina; Ward, Ryan D; Shahan, Timothy A
2009-09-01
Stimuli uncorrelated with reinforcement have been shown to enhance response rates and resistance to disruption; however, the effects of different rates of stimulus presentations have not been assessed. In two experiments, we assessed the effects of adding different rates of response-dependent brief stimuli uncorrelated with primary reinforcement on relative response rates and resistance to change. In both experiments, pigeons responded on variable-interval 60-s schedules of food reinforcement in two components of a multiple schedule, and brief response-dependent keylight-color changes were added to one or both components. Although relative response rates were not systematically affected in either experiment, relative resistance to presession feeding and extinction were. In Experiment 1, adding stimuli on a variable-interval schedule to one component of a multiple schedule either at a low rate (1 per min) for one group or at a high rate (4 per min) for another group similarly increased resistance to disruption in the components with added stimuli. When high and low rates of stimuli were presented across components (i.e., within subjects) in Experiment 2, however, relative resistance to disruption was greater in the component presenting stimuli at a lower rate. These results suggest that stimuli uncorrelated with food reinforcement do not strengthen responding in the same way as primary reinforcers.
Li, Guo; Lv, Fei; Guan, Xu
2014-01-01
This paper investigates a collaborative scheduling model in the assembly system, wherein multiple suppliers have to deliver their components to the multiple manufacturers under the operation of Supply-Hub. We first develop two different scenarios to examine the impact of Supply-Hub. One is that suppliers and manufacturers make their decisions separately, and the other is that the Supply-Hub makes joint decisions with collaborative scheduling. The results show that our scheduling model with the Supply-Hub is a NP-complete problem, therefore, we propose an auto-adapted differential evolution algorithm to solve this problem. Moreover, we illustrate that the performance of collaborative scheduling by the Supply-Hub is superior to separate decision made by each manufacturer and supplier. Furthermore, we also show that the algorithm proposed has good convergence and reliability, which can be applicable to more complicated supply chain environment.
Lv, Fei; Guan, Xu
2014-01-01
This paper investigates a collaborative scheduling model in the assembly system, wherein multiple suppliers have to deliver their components to the multiple manufacturers under the operation of Supply-Hub. We first develop two different scenarios to examine the impact of Supply-Hub. One is that suppliers and manufacturers make their decisions separately, and the other is that the Supply-Hub makes joint decisions with collaborative scheduling. The results show that our scheduling model with the Supply-Hub is a NP-complete problem, therefore, we propose an auto-adapted differential evolution algorithm to solve this problem. Moreover, we illustrate that the performance of collaborative scheduling by the Supply-Hub is superior to separate decision made by each manufacturer and supplier. Furthermore, we also show that the algorithm proposed has good convergence and reliability, which can be applicable to more complicated supply chain environment. PMID:24892104
Enabling a New Planning and Scheduling Paradigm
NASA Technical Reports Server (NTRS)
Jaap, John; Davis, Elizabeth
2004-01-01
The Flight Projects Directorate at NASA's Marshall Space Flight Center is developing a new planning and scheduling environment and a new scheduling algorithm to enable a paradigm shift in planning and scheduling concepts. Over the past 33 years Marshall has developed and evolved a paradigm for generating payload timelines for Skylab, Spacelab, various other Shuttle payloads, and the International Space Station. The current paradigm starts by collecting the requirements, called "tasks models," from the scientists and technologists for the tasks that they want to be done. Because of shortcomings in the current modeling schema, some requirements are entered as notes. Next a cadre with knowledge of vehicle and hardware modifies these models to encompass and be compatible with the hardware model; again, notes are added when the modeling schema does not provide a better way to represent the requirements. Finally, another cadre further modifies the models to be compatible with the scheduling engine. This last cadre also submits the models to the scheduling engine or builds the timeline manually to accommodate requirements that are expressed in notes. A future paradigm would provide a scheduling engine that accepts separate science models and hardware models. The modeling schema would have the capability to represent all the requirements without resorting to notes. Furthermore, the scheduling engine would not require that the models be modified to account for the capabilities (limitations) of the scheduling engine. The enabling technology under development at Marshall has three major components. (1) A new modeling schema allows expressing all the requirements of the tasks without resorting to notes or awkward contrivances. The chosen modeling schema is both maximally expressive and easy to use. It utilizes graphics methods to show hierarchies of task constraints and networks of temporal relationships. (2) A new scheduling algorithm automatically schedules the models without the intervention of a scheduling expert. The algorithm is tuned for the constraint hierarchies and the complex temporal relationships provided by the modeling schema. It has an extensive search algorithm which can exploit timing flexibilities and constraint and relationship options. (3) A web-based architecture allows multiple remote users to simultaneously model science and technology requirements and other users to model vehicle and hardware characteristics. The architecture allows the users to submit scheduling requests directly to the scheduling engine and immediately see the results. These three components are integrated so that science and technology experts with no knowledge of the vehicle or hardware subsystems and no knowledge of the internal workings of the scheduling engine have the ability to build and submit scheduling requests and see the results. The immediate feedback will hone the users' modeling skills and ultimately enable them to produce the desired timeline. This paper summarizes the three components of the enabling technology and describes how this technology would make a new paradigm possible.
Response Strength in Extreme Multiple Schedules
McLean, Anthony P; Grace, Randolph C; Nevin, John A
2012-01-01
Four pigeons were trained in a series of two-component multiple schedules. Reinforcers were scheduled with random-interval schedules. The ratio of arranged reinforcer rates in the two components was varied over 4 log units, a much wider range than previously studied. When performance appeared stable, prefeeding tests were conducted to assess resistance to change. Contrary to the generalized matching law, logarithms of response ratios in the two components were not a linear function of log reinforcer ratios, implying a failure of parameter invariance. Over a 2 log unit range, the function appeared linear and indicated undermatching, but in conditions with more extreme reinforcer ratios, approximate matching was observed. A model suggested by McLean (1991), originally for local contrast, predicts these changes in sensitivity to reinforcer ratios somewhat better than models by Herrnstein (1970) and by Williams and Wixted (1986). Prefeeding tests of resistance to change were conducted at each reinforcer ratio, and relative resistance to change was also a nonlinear function of log reinforcer ratios, again contrary to conclusions from previous work. Instead, the function suggests that resistance to change in a component may be determined partly by the rate of reinforcement and partly by the ratio of reinforcers to responses. PMID:22287804
Contextual Influences on Resistance to Disruption in Children with Intellectual Disabilities
ERIC Educational Resources Information Center
Lionello-DeNolf, Karen; Dube, William V.
2011-01-01
Training context can influence resistance to disruption under differing reinforcement schedules. With nonhumans, when relatively lean and rich reinforcement schedules are experienced in the context of a multiple schedule, greater resistance is found in the rich than the lean component, as described by behavioral momentum theory. By contrast, when…
ERIC Educational Resources Information Center
Harris, Aimee; Foster, T. Mary; Levine, Joshua; Temple, William
2012-01-01
Domestic hens responded under multiple fixed-ratio fixed-ratio schedules with equal fixed ratios. One component provided immediate reinforcement and the other provided reinforcement after a delay, signaled by the offset of the key light. The components were presented quasi-randomly so that all four possible transitions occurred in each session.…
Belke, Terry W; Pierce, W David
2014-03-01
The current study investigated the effect of motivational manipulations on operant wheel running for sucrose reinforcement and on wheel running as a behavioral consequence for lever pressing, within the same experimental context. Specifically, rats responded on a two-component multiple schedule of reinforcement in which lever pressing produced the opportunity to run in a wheel in one component of the schedule (reinforcer component) and wheel running produced the opportunity to consume sucrose solution in the other component (operant component). Motivational manipulations involved removal of sucrose contingent on wheel running and providing 1h of pre-session wheel running. Results showed that, in opposition to a response strengthening view, sucrose did not maintain operant wheel running. The motivational operations of withdrawing sucrose or providing pre-session wheel running, however, resulted in different wheel-running rates in the operant and reinforcer components of the multiple schedule; this rate discrepancy revealed the extrinsic reinforcing effects of sucrose on operant wheel running, but also indicated the intrinsic reinforcement value of wheel running across components. Differences in wheel-running rates between components were discussed in terms of arousal, undermining of intrinsic motivation, and behavioral contrast. Copyright © 2013 Elsevier B.V. All rights reserved.
Pigeons' Choices between Fixed-Interval and Random-Interval Schedules: Utility of Variability?
ERIC Educational Resources Information Center
Andrzejewski, Matthew E.; Cardinal, Claudia D.; Field, Douglas P.; Flannery, Barbara A.; Johnson, Michael; Bailey, Kathleen; Hineline, Philip N.
2005-01-01
Pigeons' choosing between fixed-interval and random-interval schedules of reinforcement was investigated in three experiments using a discrete-trial procedure. In all three experiments, the random-interval schedule was generated by sampling a probability distribution at an interval (and in multiples of the interval) equal to that of the…
Influence of temporal context on value in the multiple-chains and successive-encounters procedures.
O'Daly, Matthew; Angulo, Samuel; Gipson, Cassandra; Fantino, Edmund
2006-05-01
This set of studies explored the influence of temporal context across multiple-chain and multiple-successive-encounters procedures. Following training with different temporal contexts, the value of stimuli sharing similar reinforcement schedules was assessed by presenting these stimuli in concurrent probes. The results for the multiple-chain schedule indicate that temporal context does impact the value of a conditioned reinforcer consistent with delay-reduction theory, such that a stimulus signaling a greater reduction in delay until reinforcement has greater value. Further, nonreinforced stimuli that are concurrently presented with the preferred terminal link also have greater value, consistent with value transfer. The effects of context on value for conditions with the multiple-successive-encounters procedure, however, appear to depend on whether the search schedule or alternate handling schedule was manipulated, as well as on whether the tested stimuli were the rich or lean schedules in their components. Overall, the results help delineate the conditions under which temporal context affects conditioned-reinforcement value (acting as a learning variable) and the conditions under which it does not (acting as a performance variable), an issue of relevance to theories of choice.
JCL Implementation On A Human Spaceflight Program
NASA Technical Reports Server (NTRS)
Kulpa, Vyga; Karpowich, Mike; Abel, Diana; Archiable, Wes; Carson, William
2013-01-01
Joint Confidence Level (JCL) analysis focuses on the integration of traditionally stove-piped programmatic components (schedule, cost and risk) to establish projected resource and schedule requirements at various confidence levels and to identify programmatic cost and schedule risk drivers. SLS Program consists of multiple Prime Contractors managed by independent SLS Elements which are integrated using SE&I and Program Management. SLS further integrates with GSDO and MPCV through ESD integrated working groups.
The LSST Scheduler from design to construction
NASA Astrophysics Data System (ADS)
Delgado, Francisco; Reuter, Michael A.
2016-07-01
The Large Synoptic Survey Telescope (LSST) will be a highly robotic facility, demanding a very high efficiency during its operation. To achieve this, the LSST Scheduler has been envisioned as an autonomous software component of the Observatory Control System (OCS), that selects the sequence of targets in real time. The Scheduler will drive the survey using optimization of a dynamic cost function of more than 200 parameters. Multiple science programs produce thousands of candidate targets for each observation, and multiple telemetry measurements are received to evaluate the external and the internal conditions of the observatory. The design of the LSST Scheduler started early in the project supported by Model Based Systems Engineering, detailed prototyping and scientific validation of the survey capabilities required. In order to build such a critical component, an agile development path in incremental releases is presented, integrated to the development plan of the Operations Simulator (OpSim) to allow constant testing, integration and validation in a simulated OCS environment. The final product is a Scheduler that is also capable of running 2000 times faster than real time in simulation mode for survey studies and scientific validation during commissioning and operations.
Does the context of reinforcement affect resistance to change?
Nevin, J A; Grace, R C
1999-04-01
Eight pigeons were trained on multiple schedules of reinforcement where pairs of components alternated in blocks on different keys to define 2 local contexts. On 1 key, components arranged 160 and 40 reinforcers/hr; on the other, components arranged 40 and 10 reinforcers/hr. Response rates in the 40/hr component were higher in the latter pair. Within pairs, resistance to prefeeding and resistance to extinction were generally greater in the richer component. The two 40/hr components did not differ in resistance to prefeeding, but the 40/hr component that alternated with 10/hr was more resistant to extinction. This discrepancy was interpreted by an algebraic model relating response strength to component reinforcer rate, including generalization decrement. According to this model, strength is independent of context, consistent with research on schedule preference.
Lanovaz, Marc J; Fletcher, Sarah E; Rapp, John T
2009-09-01
We used a three-component multiple-schedule with a brief reversal design to evaluate the effects of structurally unmatched and matched stimuli on immediate and subsequent vocal stereotypy that was displayed by three children with autism spectrum disorders. For 2 of the 3 participants, access to matched stimuli, unmatched stimuli, and music decreased immediate levels of vocal stereotypy; however, with the exception of matched stimuli for one participant, none of the stimuli produced a clear abolishing operation for subsequent vocal stereotypy. That is, vocal stereotypy typically increased to baseline levels shortly after alternative stimulation was removed. Detection of motivating operations for each participant's vocal stereotypy was aided by the analysis of component distributions. The results are discussed in terms of immediate and subsequent effects of preferred stimuli on automatically reinforced problem behavior.
Combinations of response-reinforcer relations in periodic and aperiodic schedules.
Kuroda, Toshikazu; Cançado, Carlos R X; Lattal, Kennon A; Elcoro, Mirari; Dickson, Chata A; Cook, James E
2013-03-01
Key pecking of 4 pigeons was studied under a two-component multiple schedule in which food deliveries were arranged according to a fixed and a variable interfood interval. The percentage of response-dependent food in each component was varied, first in ascending (0, 10, 30, 70 and 100%) and then in descending orders, in successive conditions. The change in response rates was positively related to the percentage of response-dependent food in each schedule component. Across conditions, positively accelerated and linear patterns of responding occurred consistently in the fixed and variable components, respectively. These results suggest that the response-food dependency determines response rates in periodic and aperiodic schedules, and that the temporal distribution of food determines response patterns independently of the response-food dependency. Running rates, but not postfood pauses, also were positively related to the percentage of dependent food in each condition, in both fixed and variable components. Thus, the relation between overall response rate and the percentage of dependent food was mediated by responding that occurred after postfood pausing. The findings together extend previous studies wherein the dependency was either always present or absent, and increase the generality of the effects of variations in the response-food dependency from aperiodic to periodic schedules. © Society for the Experimental Analysis of Behavior.
Measuring Resistance to Change at the Within-Session Level
ERIC Educational Resources Information Center
Tonneau, Francois; Rios, Americo; Cabrera, Felipe
2006-01-01
Resistance to change is often studied by measuring response rate in various components of a multiple schedule. Response rate in each component is normalized (that is, divided by its baseline level) and then log-transformed. Differential resistance to change is demonstrated if the normalized, log-transformed response rate in one component decreases…
Foster, T A; Hackenberg, T D; Vaidya, M
2001-09-01
Pigeons' key pecks produced food under second-order schedules of token reinforcement, with light-emitting diodes serving as token reinforcers. In Experiment 1, tokens were earned according to a fixed-ratio 50 schedule and were exchanged for food according to either fixed-ratio or variable-ratio exchange schedules, with schedule type varied across conditions. In Experiment 2, schedule type was varied within sessions using a multiple schedule. In one component, tokens were earned according to a fixed-ratio 50 schedule and exchanged according to a variable-ratio schedule. In the other component, tokens were earned according to a variable-ratio 50 schedule and exchanged according to a fixed-ratio schedule. In both experiments, the number of responses per exchange was varied parametrically across conditions, ranging from 50 to 400 responses. Response rates decreased systematically with increases in the fixed-ratio exchange schedules, but were much less affected by changes in the variable-ratio exchange schedules. Response rates were consistently higher under variable-ratio exchange schedules than tinder comparable fixed-ratio exchange schedules, especially at higher exchange ratios. These response-rate differences were due both to greater pre-ratio pausing and to lower local rates tinder the fixed-ratio exchange schedules. Local response rates increased with proximity to food under the higher fixed-ratio exchange schedules, indicative of discriminative control by the tokens.
Resistance to Change and Relapse of Observing
ERIC Educational Resources Information Center
Thrailkill, Eric A.; Shahan, Timothy A.
2012-01-01
Four experiments examined relapse of extinguished observing behavior of pigeons using a two-component multiple schedule of observing-response procedures. In both components, unsignaled periods of variable-interval (VI) food reinforcement alternated with extinction and observing responses produced stimuli associated with the availability of the VI…
Pavor nocturnus: a complication of single daily tricyclic or neuroleptic dosage.
Flemenbaum, A
1976-05-01
The author tested the hypothesis that a single bedtime dosage schedule of tricyclic or neuroleptic medication produces increased frequency of night terrors by administering a questionnaire to 30 medical patients who were not receiving such medications and 100 psychiatric patients on either multiple- or single-dosage schedules. Psychiatric patients on multiple-dosage schedules reported no more frightening dreams than the medical patients, whereas almost three-fourths of those receiving single bedtime doses had frightening dreams, a significant difference from the medical sample. This preliminary report is presented to call attention to the possible undesirable effects of a single dose schedule.
ERIC Educational Resources Information Center
Koyama, Takanori; Wang, Hui-Ting
2011-01-01
A literature review was conducted on the effectiveness of activity schedules. Twenty three studies that a) were peer-reviewed, b) were experimental, c) implemented activity schedule as a primary intervention, d) incorporated multiple activities, and e) aimed to teach learners to self-manage individual schedules were included in the review. The…
Challenges in early clinical development of adjuvanted vaccines.
Della Cioppa, Giovanni; Jonsdottir, Ingileif; Lewis, David
2015-06-08
A three-step approach to the early development of adjuvanted vaccine candidates is proposed, the goal of which is to allow ample space for exploratory and hypothesis-generating human experiments and to select dose(s) and dosing schedule(s) to bring into full development. Although the proposed approach is more extensive than the traditional early development program, the authors suggest that by addressing key questions upfront the overall time, size and cost of development will be reduced and the probability of public health advancement enhanced. The immunogenicity end-points chosen for early development should be critically selected: an established immunological parameter with a well characterized assay should be selected as primary end-point for dose and schedule finding; exploratory information-rich end-points should be limited in number and based on pre-defined hypothesis generating plans, including system biology and pathway analyses. Building a pharmacodynamic profile is an important aspect of early development: to this end, multiple early (within 24h) and late (up to one year) sampling is necessary, which can be accomplished by sampling subgroups of subjects at different time points. In most cases the final target population, even if vulnerable, should be considered for inclusion in early development. In order to obtain the multiple formulations necessary for the dose and schedule finding, "bed-side mixing" of various components of the vaccine is often necessary: this is a complex and underestimated area that deserves serious research and logistical support. Copyright © 2015 Elsevier Ltd. All rights reserved.
Morphine Tolerance as a Function of Ratio Schedule: Response Requirement or Unit Price?
ERIC Educational Resources Information Center
Hughes, Christine; Sigmon, Stacey C.; Pitts, Raymond C.; Dykstra, Linda A.
2005-01-01
Key pecking by 3 pigeons was maintained by a multiple fixed-ratio 10, fixed-ratio 30, fixed-ratio 90 schedule of food presentation. Components differed with respect to amount of reinforcement, such that the unit price was 10 responses per 1-s access to food. Acute administration of morphine, "l"-methadone, and cocaine dose-dependently decreased…
2006-06-01
of the system (up to 3 years depending on the profiling schedule ). Shortly after deployment, each ITP begins profiling the water column at its...was programmed with accelerated sampling schedules of multiple one-way traverses per day between 10 and 750-760 m depth in order to quickly evaluate endurance and component fatigue.
NASA Technical Reports Server (NTRS)
Thalman, Nancy E.; Sparn, Thomas P.
1990-01-01
SURE (Science User Resource Expert) is one of three components that compose the SURPASS (Science User Resource Planning and Scheduling System). This system is a planning and scheduling tool which supports distributed planning and scheduling, based on resource allocation and optimization. Currently SURE is being used within the SURPASS by the UARS (Upper Atmospheric Research Satellite) SOLSTICE instrument to build a daily science plan and activity schedule and in a prototyping effort with NASA GSFC to demonstrate distributed planning and scheduling for the SOLSTICE II instrument on the EOS platform. For the SOLSTICE application the SURE utilizes a rule-based system. Development of a rule-based program using Ada CLIPS as opposed to using conventional programming, allows for capture of the science planning and scheduling heuristics in rules and provides flexibility in inserting or removing rules as the scientific objectives and mission constraints change. The SURE system's role as a component in the SURPASS, the purpose of the SURE planning and scheduling tool, the SURE knowledge base, and the software architecture of the SURE component are described.
Assessment of New Load Schedules for the Machine Calibration of a Force Balance
NASA Technical Reports Server (NTRS)
Ulbrich, N.; Gisler, R.; Kew, R.
2015-01-01
New load schedules for the machine calibration of a six-component force balance are currently being developed and evaluated at the NASA Ames Balance Calibration Laboratory. One of the proposed load schedules is discussed in the paper. It has a total of 2082 points that are distributed across 16 load series. Several criteria were applied to define the load schedule. It was decided, for example, to specify the calibration load set in force balance format as this approach greatly simplifies the definition of the lower and upper bounds of the load schedule. In addition, all loads are assumed to be applied in a calibration machine by using the one-factor-at-a-time approach. At first, all single-component loads are applied in six load series. Then, three two-component load series are applied. They consist of the load pairs (N1, N2), (S1, S2), and (RM, AF). Afterwards, four three-component load series are applied. They consist of the combinations (N1, N2, AF), (S1, S2, AF), (N1, N2, RM), and (S1, S2, RM). In the next step, one four-component load series is applied. It is the load combination (N1, N2, S1, S2). Finally, two five-component load series are applied. They are the load combination (N1, N2, S1, S2, AF) and (N1, N2, S1, S2, RM). The maximum difference between loads of two subsequent data points of the load schedule is limited to 33 % of capacity. This constraint helps avoid unwanted load "jumps" in the load schedule that can have a negative impact on the performance of a calibration machine. Only loadings of the single- and two-component load series are loaded to 100 % of capacity. This approach was selected because it keeps the total number of calibration points to a reasonable limit while still allowing for the application of some of the more complex load combinations. Data from two of NASA's force balances is used to illustrate important characteristics of the proposed 2082-point calibration load schedule.
Choice between Single and Multiple Reinforcers in Concurrent-Chains Schedules
ERIC Educational Resources Information Center
Mazur, James E.
2006-01-01
Pigeons responded on concurrent-chains schedules with equal variable-interval schedules as initial links. One terminal link delivered a single reinforcer after a fixed delay, and the other terminal link delivered either three or five reinforcers, each preceded by a fixed delay. Some conditions included a postreinforcer delay after the single…
Effects of "D"-Amphetamine and Ethanol on Variable and Repetitive Key-Peck Sequences in Pigeons
ERIC Educational Resources Information Center
Ward, Ryan D.; Bailey, Ericka M.; Odum, Amy L.
2006-01-01
This experiment assessed the effects of "d"-Amphetamine and ethanol on reinforced variable and repetitive key-peck sequences in pigeons. Pigeons responded on two keys under a multiple schedule of Repeat and Vary components. In the Repeat component, completion of a target sequence of right, right, left, left resulted in food. In the Vary component,…
A particle swarm model for estimating reliability and scheduling system maintenance
NASA Astrophysics Data System (ADS)
Puzis, Rami; Shirtz, Dov; Elovici, Yuval
2016-05-01
Modifying data and information system components may introduce new errors and deteriorate the reliability of the system. Reliability can be efficiently regained with reliability centred maintenance, which requires reliability estimation for maintenance scheduling. A variant of the particle swarm model is used to estimate reliability of systems implemented according to the model view controller paradigm. Simulations based on data collected from an online system of a large financial institute are used to compare three component-level maintenance policies. Results show that appropriately scheduled component-level maintenance greatly reduces the cost of upholding an acceptable level of reliability by reducing the need in system-wide maintenance.
Resistance to Change and Preference for Variable versus Fixed Response Sequences
ERIC Educational Resources Information Center
Arantes, Joana; Berg, Mark E.; Le, Dien; Grace, Randolph C.
2012-01-01
In Experiment 1, 4 pigeons were trained on a multiple chain schedule in which the initial link was a variable-interval (VI) 20-s schedule signalled by a red or green center key, and terminal links required four responses made to the left (L) and/or right (R) keys. In the REPEAT component, signalled by red keylights, only LRLR terminal-link…
Objectively Optimized Observation Direction System Providing Situational Awareness for a Sensor Web
NASA Astrophysics Data System (ADS)
Aulov, O.; Lary, D. J.
2010-12-01
There is great utility in having a flexible and automated objective observation direction system for the decadal survey missions and beyond. Such a system allows us to optimize the observations made by suite of sensors to address specific goals from long term monitoring to rapid response. We have developed such a prototype using a network of communicating software elements to control a heterogeneous network of sensor systems, which can have multiple modes and flexible viewing geometries. Our system makes sensor systems intelligent and situationally aware. Together they form a sensor web of multiple sensors working together and capable of automated target selection, i.e. the sensors “know” where they are, what they are able to observe, what targets and with what priorities they should observe. This system is implemented in three components. The first component is a Sensor Web simulator. The Sensor Web simulator describes the capabilities and locations of each sensor as a function of time, whether they are orbital, sub-orbital, or ground based. The simulator has been implemented using AGIs Satellite Tool Kit (STK). STK makes it easy to analyze and visualize optimal solutions for complex space scenarios, and perform complex analysis of land, sea, air, space assets, and shares results in one integrated solution. The second component is target scheduler that was implemented with STK Scheduler. STK Scheduler is powered by a scheduling engine that finds better solutions in a shorter amount of time than traditional heuristic algorithms. The global search algorithm within this engine is based on neural network technology that is capable of finding solutions to larger and more complex problems and maximizing the value of limited resources. The third component is a modeling and data assimilation system. It provides situational awareness by supplying the time evolution of uncertainty and information content metrics that are used to tell us what we need to observe and the priority we should give to the observations. A prototype of this component was implemented with AutoChem. AutoChem is NASA release software constituting an automatic code generation, symbolic differentiator, analysis, documentation, and web site creation tool for atmospheric chemical modeling and data assimilation. Its model is explicit and uses an adaptive time-step, error monitoring time integration scheme for stiff systems of equations. AutoChem was the first model to ever have the facility to perform 4D-Var data assimilation and Kalman filter. The project developed a control system with three main accomplishments. First, fully multivariate observational and theoretical information with associated uncertainties was combined using a full Kalman filter data assimilation system. Second, an optimal distribution of the computations and of data queries was achieved by utilizing high performance computers/load balancing and a set of automatically mirrored databases. Third, inter-instrument bias correction was performed using machine learning. The PI for this project was Dr. David Lary of the UMBC Joint Center for Earth Systems Technology at NASA/Goddard Space Flight Center.
ERIC Educational Resources Information Center
Wu, Will F. W.; Magill, Richard A.
2011-01-01
For this study, we investigated the effects of self-controlled practice on learning multiple motor skills. Thirty participants were randomly assigned to self-control or yoked conditions. Participants learned a three-keystroke pattern with three different relative time structures. Those in the self-control group chose one of three relative time…
Chemotherapy and treatment scheduling: the Johns Hopkins Oncology Center Outpatient Department.
Majidi, F.; Enterline, J. P.; Ashley, B.; Fowler, M. E.; Ogorzalek, L. L.; Gaudette, R.; Stuart, G. J.; Fulton, M.; Ettinger, D. S.
1993-01-01
The Chemotherapy and Treatment Scheduling System provides integrated appointment and facility scheduling for very complex procedures. It is fully integrated with other scheduling systems at The Johns Hopkins Oncology Center and is supported by the Oncology Clinical Information System (OCIS). It provides a combined visual and textual environment for the scheduling of events that have multiple dimensions and dependencies on other scheduled events. It is also fully integrated with other clinical decision support and ancillary systems within OCIS. The system has resulted in better patient flow through the ambulatory care areas of the Center. Implementing the system required changes in behavior among physicians, staff, and patients. This system provides a working example of building a sophisticated rule-based scheduling system using a relatively simple paradigm. It also is an example of what can be achieved when there is total integration between the operational and clinical components of patient care automation. PMID:8130453
NASA Astrophysics Data System (ADS)
Delgado, Francisco; Schumacher, German
2014-08-01
The Large Synoptic Survey Telescope (LSST) is a complex system of systems with demanding performance and operational requirements. The nature of its scientific goals requires a special Observatory Control System (OCS) and particularly a very specialized automatic Scheduler. The OCS Scheduler is an autonomous software component that drives the survey, selecting the detailed sequence of visits in real time, taking into account multiple science programs, the current external and internal conditions, and the history of observations. We have developed a SysML model for the OCS Scheduler that fits coherently in the OCS and LSST integrated model. We have also developed a prototype of the Scheduler that implements the scheduling algorithms in the simulation environment provided by the Operations Simulator, where the environment and the observatory are modeled with real weather data and detailed kinematics parameters. This paper expands on the Scheduler architecture and the proposed algorithms to achieve the survey goals.
Patient-Centered Appointment Scheduling Using Agent-Based Simulation
Turkcan, Ayten; Toscos, Tammy; Doebbeling, Brad N.
2014-01-01
Enhanced access and continuity are key components of patient-centered care. Existing studies show that several interventions such as providing same day appointments, walk-in services, after-hours care, and group appointments, have been used to redesign the healthcare systems for improved access to primary care. However, an intervention focusing on a single component of care delivery (i.e. improving access to acute care) might have a negative impact other components of the system (i.e. reduced continuity of care for chronic patients). Therefore, primary care clinics should consider implementing multiple interventions tailored for their patient population needs. We collected rapid ethnography and observations to better understand clinic workflow and key constraints. We then developed an agent-based simulation model that includes all access modalities (appointments, walk-ins, and after-hours access), incorporate resources and key constraints and determine the best appointment scheduling method that improves access and continuity of care. This paper demonstrates the value of simulation models to test a variety of alternative strategies to improve access to care through scheduling. PMID:25954423
Nonuniform sampling by quantiles.
Craft, D Levi; Sonstrom, Reilly E; Rovnyak, Virginia G; Rovnyak, David
2018-03-01
A flexible strategy for choosing samples nonuniformly from a Nyquist grid using the concept of statistical quantiles is presented for broad classes of NMR experimentation. Quantile-directed scheduling is intuitive and flexible for any weighting function, promotes reproducibility and seed independence, and is generalizable to multiple dimensions. In brief, weighting functions are divided into regions of equal probability, which define the samples to be acquired. Quantile scheduling therefore achieves close adherence to a probability distribution function, thereby minimizing gaps for any given degree of subsampling of the Nyquist grid. A characteristic of quantile scheduling is that one-dimensional, weighted NUS schedules are deterministic, however higher dimensional schedules are similar within a user-specified jittering parameter. To develop unweighted sampling, we investigated the minimum jitter needed to disrupt subharmonic tracts, and show that this criterion can be met in many cases by jittering within 25-50% of the subharmonic gap. For nD-NUS, three supplemental components to choosing samples by quantiles are proposed in this work: (i) forcing the corner samples to ensure sampling to specified maximum values in indirect evolution times, (ii) providing an option to triangular backfill sampling schedules to promote dense/uniform tracts at the beginning of signal evolution periods, and (iii) providing an option to force the edges of nD-NUS schedules to be identical to the 1D quantiles. Quantile-directed scheduling meets the diverse needs of current NUS experimentation, but can also be used for future NUS implementations such as off-grid NUS and more. A computer program implementing these principles (a.k.a. QSched) in 1D- and 2D-NUS is available under the general public license. Copyright © 2018 Elsevier Inc. All rights reserved.
Nonuniform sampling by quantiles
NASA Astrophysics Data System (ADS)
Craft, D. Levi; Sonstrom, Reilly E.; Rovnyak, Virginia G.; Rovnyak, David
2018-03-01
A flexible strategy for choosing samples nonuniformly from a Nyquist grid using the concept of statistical quantiles is presented for broad classes of NMR experimentation. Quantile-directed scheduling is intuitive and flexible for any weighting function, promotes reproducibility and seed independence, and is generalizable to multiple dimensions. In brief, weighting functions are divided into regions of equal probability, which define the samples to be acquired. Quantile scheduling therefore achieves close adherence to a probability distribution function, thereby minimizing gaps for any given degree of subsampling of the Nyquist grid. A characteristic of quantile scheduling is that one-dimensional, weighted NUS schedules are deterministic, however higher dimensional schedules are similar within a user-specified jittering parameter. To develop unweighted sampling, we investigated the minimum jitter needed to disrupt subharmonic tracts, and show that this criterion can be met in many cases by jittering within 25-50% of the subharmonic gap. For nD-NUS, three supplemental components to choosing samples by quantiles are proposed in this work: (i) forcing the corner samples to ensure sampling to specified maximum values in indirect evolution times, (ii) providing an option to triangular backfill sampling schedules to promote dense/uniform tracts at the beginning of signal evolution periods, and (iii) providing an option to force the edges of nD-NUS schedules to be identical to the 1D quantiles. Quantile-directed scheduling meets the diverse needs of current NUS experimentation, but can also be used for future NUS implementations such as off-grid NUS and more. A computer program implementing these principles (a.k.a. QSched) in 1D- and 2D-NUS is available under the general public license.
Intravenous Alcohol Self-Administration in the P Rat
Windisch, Kyle A.; Kosobud, Ann E. K.; Czachowski, Cristine L.
2014-01-01
Alcohol consumption produces a complex array of effects that can be divided into two types: the explicit pharmacological effects of ethanol (which can be temporally separate from time of intake) and the more temporally “relevant” effects (primarily olfactory and taste) that bridge the time from intake to onset of the pharmacological effects. Intravenous (IV) self-administration of ethanol limits the confounding “non-pharmacological” effects associated with oral consumption, allows for controlled and precise dosing, and bypasses first order absorption kinetics, allowing for more direct and better-controlled assessment of alcohol’s effect on the brain. IV ethanol self-administration has been reliably demonstrated in mouse and human experimental models; however, models of IV self-administration have been historically problematic in the rat. An operant multiple-schedule study design was used to elucidate the role of each component of a compound IV-ethanol plus oral-sucrose reinforcer. Male alcohol-preferring P rats had free access to both food and water during all IV self-administration sessions. Animals were trained to press a lever for orally delivered 1% sucrose (1S) on a fixed ratio 4 schedule, and then surgically implanted with an indwelling jugular catheter. Animals were then trained to respond on a multiple FR4-FR4 schedule composed of alternating 2.5-min components across 30-min sessions. For the multiple schedule, two components were used: an oral 1S only and an oral 1S plus IV 20% ethanol (25 mg/kg/injection). Average total ethanol intake was 0.47 ± 0.04 g/kg. We found significantly higher earning of sucrose-only reinforcers and greater sucrose-lever error responding relative to the compound oral-sucrose plus IV-ethanol reinforcer. These response patterns suggest that sucrose, not ethanol, was responsible for driving overall responding. The work with a compound IV ethanol-oral sucrose reinforcer presented here suggests that the existing intravenous ethanol self-administration methodology cannot overcome the aversive properties of ethanol via this route in the rat. PMID:24835637
77 FR 43084 - Multiple Award Schedule (MAS) Program Continuous Open Season-Operational Change
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-23
... Award Schedule (MAS) Program Continuous Open Season- Operational Change AGENCY: Federal Acquisition... proposing this operational change to enhance the performance of and modernize the MAS program in three key program areas: Small business viability, operational efficiency, and cost control. The DBM will realign...
Stubbs, D A; Cohen, S L
1972-11-01
Pigeons performed on a second-order schedule in which fixed-interval components were maintained under a variable-interval schedule. Completion of each fixed-interval component resulted in a brief-stimulus presentation and/or food. The relation of the brief stimulus and food was varied across conditions. Under some conditions, the brief stimulus was never paired with food. Under other conditions, the brief stimulus was paired with food; three different pairing procedures were used: (a) a response produced the simultaneous onset of the stimulus and food; (b) a response produced the stimulus before food with the stimulus remaining on during food presentation; (c) a response produced the stimulus and the offset of the stimulus was simultaneous with the onset of the food cycle. The various pairing and nonpairing operations all produced similar effects on performance. Under all conditions, response rates were positively accelerated within fixed-interval components. Total response rates and Index of Curvature measures were similar across conditions. In one condition, a blackout was paired with food; with this different stimulus in effect, less curvature resulted. The results suggest that pairing of a stimulus is not a necessary condition for within-component patterning under some second-order schedules.
Stubbs, D. Alan; Cohen, Steven L.
1972-01-01
Pigeons performed on a second-order schedule in which fixed-interval components were maintained under a variable-interval schedule. Completion of each fixed-interval component resulted in a brief-stimulus presentation and/or food. The relation of the brief stimulus and food was varied across conditions. Under some conditions, the brief stimulus was never paired with food. Under other conditions, the brief stimulus was paired with food; three different pairing procedures were used: (a) a response produced the simultaneous onset of the stimulus and food; (b) a response produced the stimulus before food with the stimulus remaining on during food presentation; (c) a response produced the stimulus and the offset of the stimulus was simultaneous with the onset of the food cycle. The various pairing and nonpairing operations all produced similar effects on performance. Under all conditions, response rates were positively accelerated within fixed-interval components. Total response rates and Index of Curvature measures were similar across conditions. In one condition, a blackout was paired with food; with this different stimulus in effect, less curvature resulted. The results suggest that pairing of a stimulus is not a necessary condition for within-component patterning under some second-order schedules. PMID:16811634
ERIC Educational Resources Information Center
Wakefield, James A., Jr.; Cunningham, Claude H.
1975-01-01
The Vocational Preference Inventory and the Edwards Personal Preference Schedule were administered to 372 undergraduates. The two instruments were compared using canonical analysis. The analysis revealed three significant relationships between components of the two instruments. The relationships were viewed as supportive of Holland's theory of…
Autonomous power expert system
NASA Technical Reports Server (NTRS)
Walters, Jerry L.; Petrik, Edward J.; Roth, Mary Ellen; Truong, Long Van; Quinn, Todd; Krawczonek, Walter M.
1990-01-01
The Autonomous Power Expert (APEX) system was designed to monitor and diagnose fault conditions that occur within the Space Station Freedom Electrical Power System (SSF/EPS) Testbed. APEX is designed to interface with SSF/EPS testbed power management controllers to provide enhanced autonomous operation and control capability. The APEX architecture consists of three components: (1) a rule-based expert system, (2) a testbed data acquisition interface, and (3) a power scheduler interface. Fault detection, fault isolation, justification of probable causes, recommended actions, and incipient fault analysis are the main functions of the expert system component. The data acquisition component requests and receives pertinent parametric values from the EPS testbed and asserts the values into a knowledge base. Power load profile information is obtained from a remote scheduler through the power scheduler interface component. The current APEX design and development work is discussed. Operation and use of APEX by way of the user interface screens is also covered.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Garikapati, Venu; Astroza, Sebastian; Bhat, Prerna C.
This paper is motivated by the increasing recognition that modeling activity-travel demand for a single day of the week, as is done in virtually all travel forecasting models, may be inadequate in capturing underlying processes that govern activity-travel scheduling behavior. The considerable variability in daily travel suggests that there are important complementary relationships and competing tradeoffs involved in scheduling and allocating time to various activities across days of the week. Both limited survey data availability and methodological challenges in modeling week-long activity-travel schedules have precluded the development of multi-day activity-travel demand models. With passive and technology-based data collection methods increasinglymore » in vogue, the collection of multi-day travel data may become increasingly commonplace in the years ahead. This paper addresses the methodological challenge associated with modeling multi-day activity-travel demand by formulating a multivariate multiple discrete-continuous probit (MDCP) model system. The comprehensive framework ties together two MDCP model components, one corresponding to weekday time allocation and the other to weekend activity-time allocation. By tying the two MDCP components together, the model system also captures relationships in activity-time allocation between weekdays on the one hand and weekend days on the other. Model estimation on a week-long travel diary data set from the United Kingdom shows that there are significant inter-relationships between weekdays and weekend days in activity-travel scheduling behavior. The model system presented in this paper may serve as a higher-level multi-day activity scheduler in conjunction with existing daily activity-based travel models.« less
Baseline response rates affect resistance to change.
Kuroda, Toshikazu; Cook, James E; Lattal, Kennon A
2018-01-01
The effect of response rates on resistance to change, measured as resistance to extinction, was examined in two experiments. In Experiment 1, responding in transition from a variable-ratio schedule and its yoked-interval counterpart to extinction was compared with pigeons. Following training on a multiple variable-ratio yoked-interval schedule of reinforcement, in which response rates were higher in the former component, reinforcement was removed from both components during a single extended extinction session. Resistance to extinction in the yoked-interval component was always either greater or equal to that in the variable-ratio component. In Experiment 2, resistance to extinction was compared for two groups of rats that exhibited either high or low response rates when maintained on identical variable-interval schedules. Resistance to extinction was greater for the lower-response-rate group. These results suggest that baseline response rate can contribute to resistance to change. Such effects, however, can only be revealed when baseline response rate and reinforcement rate are disentangled (Experiments 1 and 2) from the more usual circumstance where the two covary. Furthermore, they are more cleanly revealed when the programmed contingencies controlling high and low response rates are identical, as in Experiment 2. © 2017 Society for the Experimental Analysis of Behavior.
Coordinating space telescope operations in an integrated planning and scheduling architecture
NASA Technical Reports Server (NTRS)
Muscettola, Nicola; Smith, Stephen F.; Cesta, Amedeo; D'Aloisi, Daniela
1992-01-01
The Heuristic Scheduling Testbed System (HSTS), a software architecture for integrated planning and scheduling, is discussed. The architecture has been applied to the problem of generating observation schedules for the Hubble Space Telescope. This problem is representative of the class of problems that can be addressed: their complexity lies in the interaction of resource allocation and auxiliary task expansion. The architecture deals with this interaction by viewing planning and scheduling as two complementary aspects of the more general process of constructing behaviors of a dynamical system. The principal components of the software architecture are described, indicating how to model the structure and dynamics of a system, how to represent schedules at multiple levels of abstraction in the temporal database, and how the problem solving machinery operates. A scheduler for the detailed management of Hubble Space Telescope operations that has been developed within HSTS is described. Experimental performance results are given that indicate the utility and practicality of the approach.
Ward, Ryan D; Odum, Amy L
2008-01-01
The present experiment developed a methodology for assessing sensitivity of conditional-discrimination performance to within-session variation of reinforcer frequency. Four pigeons responded under a multiple schedule of matching-to-sample components in which the ratio of reinforcers for correct S1 and S2 responses was varied across components within session. Initially, five components, each arranging a different reinforcer-frequency ratio (from 1∶9 to 9∶1), were presented randomly within a session. Under this condition, sensitivity to reinforcer frequency was low. Sensitivity failed to improve after extended exposure to this condition, and under a condition in which only three reinforcer-frequency ratios were varied within session. In a later condition, three reinforcer-frequency ratios were varied within session, but the reinforcer-frequency ratio in effect was differentially signaled within each component. Under this condition, values of sensitivity were similar to those traditionally obtained when reinforcer-frequency ratios for correct responses are varied across conditions. The effects of signaled vs. unsignaled reinforcer-frequency ratios were replicated in two subsequent conditions. The present procedure could provide a practical alternative to parametric variation of reinforcer frequency across conditions and may be useful in characterizing the effects of a variety of manipulations on steady-state sensitivity to reinforcer frequency. PMID:19070338
A comparison of multiprocessor scheduling methods for iterative data flow architectures
NASA Technical Reports Server (NTRS)
Storch, Matthew
1993-01-01
A comparative study is made between the Algorithm to Architecture Mapping Model (ATAMM) and three other related multiprocessing models from the published literature. The primary focus of all four models is the non-preemptive scheduling of large-grain iterative data flow graphs as required in real-time systems, control applications, signal processing, and pipelined computations. Important characteristics of the models such as injection control, dynamic assignment, multiple node instantiations, static optimum unfolding, range-chart guided scheduling, and mathematical optimization are identified. The models from the literature are compared with the ATAMM for performance, scheduling methods, memory requirements, and complexity of scheduling and design procedures.
NASA Technical Reports Server (NTRS)
Jaap, John; Muery, Kim
2000-01-01
Scheduling engines are found at the core of software systems that plan and schedule activities and resources. A Request-Oriented Scheduling Engine (ROSE) is one that processes a single request (adding a task to a timeline) and then waits for another request. For the International Space Station, a robust ROSE-based system would support multiple, simultaneous users, each formulating requests (defining scheduling requirements), submitting these requests via the internet to a single scheduling engine operating on a single timeline, and immediately viewing the resulting timeline. ROSE is significantly different from the engine currently used to schedule Space Station operations. The current engine supports essentially one person at a time, with a pre-defined set of requirements from many payloads, working in either a "batch" scheduling mode or an interactive/manual scheduling mode. A planning and scheduling process that takes advantage of the features of ROSE could produce greater customer satisfaction at reduced cost and reduced flow time. This paper describes a possible ROSE-based scheduling process and identifies the additional software component required to support it. Resulting changes to the management and control of the process are also discussed.
Evaluation of Scheduling Methods for Multiple Runways
NASA Technical Reports Server (NTRS)
Bolender, Michael A.; Slater, G. L.
1996-01-01
Several scheduling strategies are analyzed in order to determine the most efficient means of scheduling aircraft when multiple runways are operational and the airport is operating at different utilization rates. The study compares simulation data for two and three runway scenarios to results from queuing theory for an M/D/n queue. The direction taken, however, is not to do a steady-state, or equilibrium, analysis since this is not the case during a rush period at a typical airport. Instead, a transient analysis of the delay per aircraft is performed. It is shown that the scheduling strategy that reduces the delay depends upon the density of the arrival traffic. For light traffic, scheduling aircraft to their preferred runways is sufficient; however, as the arrival rate increases, it becomes more important to separate traffic by weight class. Significant delay reduction is realized when aircraft that belong to the heavy and small weight classes are sent to separate runways with large aircraft put into the 'best' landing slot.
Intravenous alcohol self-administration in the P rat.
Windisch, Kyle A; Kosobud, Ann E K; Czachowski, Cristine L
2014-08-01
Alcohol consumption produces a complex array of effects that can be divided into two types: the explicit pharmacological effects of ethanol (which can be temporally separate from time of intake) and the more temporally "relevant" effects (primarily olfactory and taste) that bridge the time from intake to onset of the pharmacological effects. Intravenous (IV) self-administration of ethanol limits the confounding "non-pharmacological" effects associated with oral consumption, allows for controlled and precise dosing, and bypasses first order absorption kinetics, allowing for more direct and better-controlled assessment of alcohol's effect on the brain. IV ethanol self-administration has been reliably demonstrated in mouse and human experimental models; however, models of IV self-administration have been historically problematic in the rat. An operant multiple-schedule study design was used to elucidate the role of each component of a compound IV-ethanol plus oral-sucrose reinforcer. Male alcohol-preferring P rats had free access to both food and water during all IV self-administration sessions. Animals were trained to press a lever for orally delivered 1% sucrose (1S) on a fixed ratio 4 schedule, and then surgically implanted with an indwelling jugular catheter. Animals were then trained to respond on a multiple FR4-FR4 schedule composed of alternating 2.5-min components across 30-min sessions. For the multiple schedule, two components were used: an oral 1S only and an oral 1S plus IV 20% ethanol (25 mg/kg/injection). Average total ethanol intake was 0.47 ± 0.04 g/kg. We found significantly higher earning of sucrose-only reinforcers and greater sucrose-lever error responding relative to the compound oral-sucrose plus IV-ethanol reinforcer. These response patterns suggest that sucrose, not ethanol, was responsible for driving overall responding. The work with a compound IV ethanol-oral sucrose reinforcer presented here suggests that the existing intravenous ethanol self-administration methodology cannot overcome the aversive properties of ethanol via this route in the rat. Copyright © 2014 Elsevier Inc. All rights reserved.
Resistance to extinction, generalization decrement, and conditioned reinforcement.
Dulaney, Alana E; Bell, Matthew C
2008-06-01
This study investigated generalization decrement during an extinction resistance-to-change test for pigeon key pecking using a two-component multiple schedule with equal variable-interval 3-min schedules and different reinforcer amounts (one component presented 2-s access to reinforcement and the other 8s). After establishing baseline responding, subjects were assigned to one of the two extinction conditions: hopper stimuli (hopper and hopper light were activated but no food was available) or Control (inactive hopper and hopper light). Responding in the 8-s component was more resistant to extinction than responding in the 2-s component, the hopper stimuli group was more resistant to extinction compared to the Control group, and an interaction between amount of reinforcement, extinction condition, and session block was present. This finding supports generalization decrement as a factor that influences resistance to extinction. Hopper-time data (the amount of time subjects spent with their heads in the hopper) were compared to resistance-to-change data in an investigation of the role of conditioned reinforcement on resistance to change.
Study of the impact of cruise speed on scheduling and productivity of commercial transport aircraft
NASA Technical Reports Server (NTRS)
Bond, E. Q.; Carroll, E. A.; Flume, R. A.
1977-01-01
A comparison is made between airplane productivity and utilization levels derived from commercial airline type schedules which were developed for two subsonic and four supersonic cruise speed aircraft. The cruise speed component is the only difference between the schedules which are based on 1995 passenger demand forecasts. Productivity-to-speed relationships were determined for the three discrete route systems: North Atlantic, Trans-Pacific, and North-South America. Selected combinations of these route systems were also studied. Other areas affecting the productivity-to-speed relationship such as aircraft design range and scheduled turn time were examined.
Development of a Dynamic Time Sharing Scheduled Environment Final Report CRADA No. TC-824-94E
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jette, M.; Caliga, D.
Massively parallel computers, such as the Cray T3D, have historically supported resource sharing solely with space sharing. In that method, multiple problems are solved by executing them on distinct processors. This project developed a dynamic time- and space-sharing scheduler to achieve greater interactivity and throughput than could be achieved with space-sharing alone. CRI and LLNL worked together on the design, testing, and review aspects of this project. There were separate software deliverables. CFU implemented a general purpose scheduling system as per the design specifications. LLNL ported the local gang scheduler software to the LLNL Cray T3D. In this approach, processorsmore » are allocated simultaneously to aU components of a parallel program (in a “gang”). Program execution is preempted as needed to provide for interactivity. Programs are also reIocated to different processors as needed to efficiently pack the computer’s torus of processors. In phase one, CRI developed an interface specification after discussions with LLNL for systemlevel software supporting a time- and space-sharing environment on the LLNL T3D. The two parties also discussed interface specifications for external control tools (such as scheduling policy tools, system administration tools) and applications programs. CRI assumed responsibility for the writing and implementation of all the necessary system software in this phase. In phase two, CRI implemented job-rolling on the Cray T3D, a mechanism for preempting a program, saving its state to disk, and later restoring its state to memory for continued execution. LLNL ported its gang scheduler to the LLNL T3D utilizing the CRI interface implemented in phases one and two. During phase three, the functionality and effectiveness of the LLNL gang scheduler was assessed to provide input to CRI time- and space-sharing, efforts. CRI will utilize this information in the development of general schedulers suitable for other sites and future architectures.« less
Measuring Resistance to Change at the Within-Session Level
Tonneau, François; Ríos, Américo; Cabrera, Felipe
2006-01-01
Resistance to change is often studied by measuring response rate in various components of a multiple schedule. Response rate in each component is normalized (that is, divided by its baseline level) and then log-transformed. Differential resistance to change is demonstrated if the normalized, log-transformed response rate in one component decreases more slowly than in another component. A problem with normalization, however, is that it can produce artifactual results if the relation between baseline level and disruption is not multiplicative. One way to address this issue is to fit specific models of disruption to untransformed response rates and evaluate whether or not a multiplicative model accounts for the data. Here we present such a test of resistance to change, using within-session response patterns in rats as a data base for fitting models of disruption. By analyzing response rate at a within-session level, we were able to confirm a central prediction of the resistance-to-change framework while discarding normalization artifacts as a plausible explanation of our results. PMID:16903495
Measuring resistance to change at the within-session level.
Tonneau, François; Ríos, Américo; Cabrera, Felipe
2006-07-01
Resistance to change is often studied by measuring response rate in various components of a multiple schedule. Response rate in each component is normalized (that is, divided by its baseline level) and then log-transformed. Differential resistance to change is demonstrated if the normalized, log-transformed response rate in one component decreases more slowly than in another component. A problem with normalization, however, is that it can produce artifactual results if the relation between baseline level and disruption is not multiplicative. One way to address this issue is to fit specific models of disruption to untransformed response rates and evaluate whether or not a multiplicative model accounts for the data. Here we present such a test of resistance to change, using within-session response patterns in rats as a data base for fitting models of disruption. By analyzing response rate at a within-session level, we were able to confirm a central prediction of the resistance-to-change framework while discarding normalization artifacts as a plausible explanation of our results.
Luczynski, Kevin C; Hanley, Gregory P
2014-01-01
Several studies have shown that children prefer contingent reinforcement (CR) rather than yoked noncontingent reinforcement (NCR) when continuous reinforcement is programmed in the CR schedule. Preference has not, however, been evaluated for practical schedules that involve CR. In Study 1, we assessed 5 children's preference for obtaining social interaction via a multiple schedule (periods of fixed-ratio 1 reinforcement alternating with periods of extinction), a briefly signaled delayed reinforcement schedule, and an NCR schedule. The multiple schedule promoted the most efficient level of responding. In general, children chose to experience the multiple schedule and avoided the delay and NCR schedules, indicating that they preferred multiple schedules as the means to arrange practical schedules of social interaction. In Study 2, we evaluated potential controlling variables that influenced 1 child's preference for the multiple schedule and found that the strong positive contingency was the primary variable. © Society for the Experimental Analysis of Behavior.
Resistance to change and resurgence in humans engaging in a computer task.
Kuroda, Toshikazu; Cançado, Carlos R X; Podlesnik, Christopher A
2016-04-01
The relation between persistence, as measured by resistance to change, and resurgence has been examined with nonhuman animals but not systematically with humans. The present study examined persistence and resurgence with undergraduate students engaging in a computer task for points exchangeable for money. In Phase 1, a target response was maintained on a multiple variable-interval (VI) 15-s (Rich) VI 60-s (Lean) schedule of reinforcement. In Phase 2, the target response was extinguished while an alternative response was reinforced at equal rates in both schedule components. In Phase 3, the target and the alternative responses were extinguished. In an additional test of persistence (Phase 4), target responding was reestablished as in Phase 1 and then disrupted by access to videos in both schedule components. In Phases 2 and 4, target responding was more persistent in the Rich than in the Lean component. Also, resurgence generally was greater in the Rich than in the Lean component in Phase 3. The present findings with humans extend the generality of those obtained with nonhuman animals showing that higher reinforcement rates produce both greater persistence and resurgence, and suggest that common processes underlie response persistence and relapse. Copyright © 2016 Elsevier B.V. All rights reserved.
NASA Technical Reports Server (NTRS)
Hornstein, Rhoda S.; Shinkle, Gerald L.; Weiler, Jerry D.; Willoughby, John K.
1990-01-01
This paper presents a planning approach to the Space Station Freedom program which takes into account the widely distributed nature of that program. The program management structure is organized into three major levels: a strategic level, a tactical level, and an execution level. For each level, resource availabilities are determined, the resources are distributed, schedules are built independently within the resource limits, the schedules are integrated into a single schedule, and conflicts are resolved by negotiating requirements and/or relaxing contraints. This approach distributes resources to multiple planning entities in such a way that when the multiple plans are collected, they fit together with minimal modification. The up-front distribution is planned in such a way and to a sufficient degree that a fit is virtually assured.
Another look at contrast in multiple schedules
Williams, Ben A.
1983-01-01
Recent research on multiple schedule interactions is reviewed. Contrary to formulations that view contrast as the result of elicited behavior controlled by the stimulus-reinforcer contingency (e.g., additivity theory), the major controlling variable is the relative rate of reinforcement, which cannot be reduced to some combination of stimulus-reinforcer and response-reinforcer effects. Other recent theoretical formulations are also reviewed and all are found to face serious counterevidence. The best description of the available data continues to be in terms of the “context of reinforcement,” but Herrnstein's (1970) formulation of the basis of such context effects appears to be inadequate. An alternative conception is provided by Catania's concept of “inhibition by reinforcement,” by which rate of responding is inversely related to the average rate of reinforcement in the situation. Such a conception is related to Gibbon's recent scalar-expectancy account of autoshaping and Fantino's delay-reduction model of conditioned reinforcement, suggesting that a common set of principles determines several diverse conditioning phenomena. However, the empirical status of such a description remains uncertain, because recent evidence shows that schedule interactions are temporally asymmetric, depending primarily upon the conditions of reinforcement that follow a schedule component. PMID:16812325
Collecting and Using Staff Performance Information for School Improvement.
ERIC Educational Resources Information Center
Tucker, Null A.
Use of multiple data sources for evaluation of faculty performance by the DeKalb County (Georgia) School System is described. Focus is on two evaluations, the administrator evaluation and the counselor evaluation; the former has been employed longer than any other component of the evaluation system, while the latter is scheduled for its second…
Belke, Terry W; Pierce, W David
2015-07-01
As a follow up to Belke and Pierce's (2014) study, we assessed the effects of repeated presentation and removal of sucrose solution on the behavior of rats responding on a two-component multiple schedule. Rats completed 15 wheel turns (FR 15) for either 15% or 0% sucrose solution in the manipulated component and lever pressed 10 times on average (VR 10) for an opportunity to complete 15 wheel turns (FR 15) in the other component. In contrast to our earlier study, the components advanced based on time (every 8min) rather than completed responses. Results showed that in the manipulated component wheel-running rates were higher and the latency to initiate running longer when sucrose was present (15%) compared to absent (0% or water); the number of obtained outcomes (sucrose/water), however, did not differ with the presentation and withdrawal of sucrose. For the wheel-running as reinforcement component, rates of wheel turns, overall lever-pressing rates, and obtained wheel-running reinforcements were higher, and postreinforcement pauses shorter, when sucrose was present (15%) than absent (0%) in manipulated component. Overall, our findings suggest that wheel-running rate regardless of its function (operant or reinforcement) is maintained by automatically generated consequences (automatic reinforcement) and is increased as an operant by adding experimentally arranged sucrose reinforcement (extrinsic reinforcement). This additive effect on operant wheel-running generalizes through induction or arousal to the wheel-running as reinforcement component, increasing the rate of responding for opportunities to run and the rate of wheel-running per opportunity. Copyright © 2015 Elsevier B.V. All rights reserved.
Automating Mid- and Long-Range Scheduling for NASA's Deep Space Network
NASA Technical Reports Server (NTRS)
Johnston, Mark D.; Tran, Daniel; Arroyo, Belinda; Sorensen, Sugi; Tay, Peter; Carruth, Butch; Coffman, Adam; Wallace, Mike
2012-01-01
NASA has recently deployed a new mid-range scheduling system for the antennas of the Deep Space Network (DSN), called Service Scheduling Software, or S(sup 3). This system is architected as a modern web application containing a central scheduling database integrated with a collaborative environment, exploiting the same technologies as social web applications but applied to a space operations context. This is highly relevant to the DSN domain since the network schedule of operations is developed in a peer-to-peer negotiation process among all users who utilize the DSN (representing 37 projects including international partners and ground-based science and calibration users). The initial implementation of S(sup 3) is complete and the system has been operational since July 2011. S(sup 3) has been used for negotiating schedules since April 2011, including the baseline schedules for three launching missions in late 2011. S(sup 3) supports a distributed scheduling model, in which changes can potentially be made by multiple users based on multiple schedule "workspaces" or versions of the schedule. This has led to several challenges in the design of the scheduling database, and of a change proposal workflow that allows users to concur with or to reject proposed schedule changes, and then counter-propose with alternative or additional suggested changes. This paper describes some key aspects of the S(sup 3) system and lessons learned from its operational deployment to date, focusing on the challenges of multi-user collaborative scheduling in a practical and mission-critical setting. We will also describe the ongoing project to extend S(sup 3) to encompass long-range planning, downtime analysis, and forecasting, as the next step in developing a single integrated DSN scheduling tool suite to cover all time ranges.
Thompson, D M; Guidotti, A; DiBella, M; Costa, E
1995-01-01
We report here on the ability of IDRA 21 and aniracetam, two negative allosteric modulators of glutamate-induced DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization, to attenuate alprazolam-induced learning deficit in patas monkeys working in a complex behavioral task. In one component of a multiple schedule (repeated acquisition or "learning"), patas monkeys acquired a different four-response chain each session by responding sequentially on three keys in the presence of four discriminative stimuli (geometric forms or numerals). In the other component (performance) the four-response chain was the same each session. The response chain in each component was maintained by food presentation under a fixed-ratio schedule. When alprazolam (0.1 or 0.32 mg/kg p.o.) was administered alone, this full allosteric modulator of gamma-aminobutyric acid type A (GABAA) receptors produced large decreases in the response rate and accuracy in the learning component of the task. IDRA 21 (3 or 5.6 mg/kg p.o.) and aniracetam (30 mg/kg p.o.) administered 60 min before alprazolam, having no effect when given alone, antagonized the large disruptive effects of alprazolam on learning. From dose-response studies, it can be estimated that IDRA 21 is approximately 10-fold more potent than aniracetam in antagonizing alprazolam-induced learning deficit. We conclude that IDRA 21, a chemically unrelated pharmacological congener of aniracetam, improves learning deficit induced in patas monkeys by the increase of GABAergic tone elicited by alprazolam. Very likely IDRA 21 exerts its behavioral effects by antagonizing AMPA receptor desensitization. PMID:7644474
Thompson, D M; Guidotti, A; DiBella, M; Costa, E
1995-08-15
We report here on the ability of IDRA 21 and aniracetam, two negative allosteric modulators of glutamate-induced DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization, to attenuate alprazolam-induced learning deficit in patas monkeys working in a complex behavioral task. In one component of a multiple schedule (repeated acquisition or "learning"), patas monkeys acquired a different four-response chain each session by responding sequentially on three keys in the presence of four discriminative stimuli (geometric forms or numerals). In the other component (performance) the four-response chain was the same each session. The response chain in each component was maintained by food presentation under a fixed-ratio schedule. When alprazolam (0.1 or 0.32 mg/kg p.o.) was administered alone, this full allosteric modulator of gamma-aminobutyric acid type A (GABAA) receptors produced large decreases in the response rate and accuracy in the learning component of the task. IDRA 21 (3 or 5.6 mg/kg p.o.) and aniracetam (30 mg/kg p.o.) administered 60 min before alprazolam, having no effect when given alone, antagonized the large disruptive effects of alprazolam on learning. From dose-response studies, it can be estimated that IDRA 21 is approximately 10-fold more potent than aniracetam in antagonizing alprazolam-induced learning deficit. We conclude that IDRA 21, a chemically unrelated pharmacological congener of aniracetam, improves learning deficit induced in patas monkeys by the increase of GABAergic tone elicited by alprazolam. Very likely IDRA 21 exerts its behavioral effects by antagonizing AMPA receptor desensitization.
Technology Integration and the Effect on Mathematics Fact Fluency in the Middle East
ERIC Educational Resources Information Center
Letwinsky, Karim Medico; Berry, Michael David
2017-01-01
This quantitative, quasi-experimental study investigated the effect of the Mathletics.com technology on basic multiplication fact fluency in fourth grade students in the Middle East. The treatment group received three weeks of scheduled time using Mathletics.com, while the control group practiced multiplication facts using only traditional…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hummon, M.; Jorgenson, J.; Denholm, P.
2013-10-01
Concentrating solar power with thermal energy storage (CSP-TES) can provide multiple benefits to the grid, including low marginal cost energy and the ability to levelize load, provide operating reserves, and provide firm capacity. It is challenging to properly value the integration of CSP because of the complicated nature of this technology. Unlike completely dispatchable fossil sources, CSP is a limited energy resource, depending on the hourly and daily supply of solar energy. To optimize the use of this limited energy, CSP-TES must be implemented in a production cost model with multiple decision variables for the operation of the CSP-TES plant.more » We develop and implement a CSP-TES plant in a production cost model that accurately characterizes the three main components of the plant: solar field, storage tank, and power block. We show the effect of various modelling simplifications on the value of CSP, including: scheduled versus optimized dispatch from the storage tank and energy-only operation versus co-optimization with ancillary services.« less
Modelling Concentrating Solar Power with Thermal Energy Storage for Integration Studies: Preprint
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hummon, M.; Denholm, P.; Jorgenson, J.
2013-10-01
Concentrating solar power with thermal energy storage (CSP-TES) can provide multiple benefits to the grid, including low marginal cost energy and the ability to levelize load, provide operating reserves, and provide firm capacity. It is challenging to properly value the integration of CSP because of the complicated nature of this technology. Unlike completely dispatchable fossil sources, CSP is a limited energy resource, depending on the hourly and daily supply of solar energy. To optimize the use of this limited energy, CSP-TES must be implemented in a production cost model with multiple decision variables for the operation of the CSP-TES plant.more » We develop and implement a CSP-TES plant in a production cost model that accurately characterizes the three main components of the plant: solar field, storage tank, and power block. We show the effect of various modelling simplifications on the value of CSP, including: scheduled versus optimized dispatch from the storage tank and energy-only operation versus co-optimization with ancillary services.« less
Unsignaled Delay of Reinforcement, Relative Time, and Resistance to Change
ERIC Educational Resources Information Center
Shahan, Timothy A.; Lattal, Kennon A.
2005-01-01
Two experiments with pigeons examined the effects of unsignaled, nonresetting delays of reinforcement on responding maintained by different reinforcement rates. In Experiment 1, 3-s unsignaled delays were introduced into each component of a multiple variable-interval (VI) 15-s VI 90-s VI 540-s schedule. When considered as a proportion of the…
A Practical Variation of a Multiple-Schedule Procedure: Brief Schedule-Correlated Stimuli
ERIC Educational Resources Information Center
Tiger, Jeffrey H.; Hanley, Gregory P.; Larsen, Kylie M.
2008-01-01
Multiple schedules using continuous discriminative stimuli have been used to minimize children's disruptive requesting for teacher attention (e.g., colored floral leis; Tiger & Hanley, 2004; Tiger, Hanley, & Heal, 2006). The present study evaluated the effectiveness of, and children's preferences for, two multiple-schedule arrangements in which…
A novel multi-item joint replenishment problem considering multiple type discounts.
Cui, Ligang; Zhang, Yajun; Deng, Jie; Xu, Maozeng
2018-01-01
In business replenishment, discount offers of multi-item may either provide different discount schedules with a single discount type, or provide schedules with multiple discount types. The paper investigates the joint effects of multiple discount schemes on the decisions of multi-item joint replenishment. In this paper, a joint replenishment problem (JRP) model, considering three discount (all-unit discount, incremental discount, total volume discount) offers simultaneously, is constructed to determine the basic cycle time and joint replenishment frequencies of multi-item. To solve the proposed problem, a heuristic algorithm is proposed to find the optimal solutions and the corresponding total cost of the JRP model. Numerical experiment is performed to test the algorithm and the computational results of JRPs under different discount combinations show different significance in the replenishment cost reduction.
An Empirical Comparison of Maslow's and Murray's Needs Systems
ERIC Educational Resources Information Center
Cunningham, Claude H.; And Others
1975-01-01
Attempts to establish the corresponding dimensions of needs measured by the Work Motivation Inventory and the Edwards Personal Preference Schedule. Three significant relationships were found between the two components. (Author/DEP)
A Baseline Load Schedule for the Manual Calibration of a Force Balance
NASA Technical Reports Server (NTRS)
Ulbrich, N.; Gisler, R.
2013-01-01
A baseline load schedule for the manual calibration of a force balance is defined that takes current capabilities at the NASA Ames Balance Calibration Laboratory into account. The chosen load schedule consists of 18 load series with a total of 194 data points. It was designed to satisfy six requirements: (i) positive and negative loadings should be applied for each load component; (ii) at least three loadings should be applied between 0 % and 100 % load capacity; (iii) normal and side force loadings should be applied at the forward gage location, aft gage location, and the balance moment center; (iv) the balance should be used in "up" and "down" orientation to get positive and negative axial force loadings; (v) the constant normal and side force approaches should be used to get the rolling moment loadings; (vi) rolling moment loadings should be obtained for 0, 90, 180, and 270 degrees balance orientation. In addition, three different approaches are discussed in the paper that may be used to independently estimate the natural zeros, i.e., the gage outputs of the absolute load datum of the balance. These three approaches provide gage output differences that can be used to estimate the weight of both the metric and non-metric part of the balance. Data from the calibration of a six-component force balance will be used in the final manuscript of the paper to illustrate characteristics of the proposed baseline load schedule.
A subjective scheduler for subjective dedicated networks
NASA Astrophysics Data System (ADS)
Suherman; Fakhrizal, Said Reza; Al-Akaidi, Marwan
2017-09-01
Multiple access technique is one of important techniques within medium access layer in TCP/IP protocol stack. Each network technology implements the selected access method. Priority can be implemented in those methods to differentiate services. Some internet networks are dedicated for specific purpose. Education browsing or tutorial video accesses are preferred in a library hotspot, while entertainment and sport contents could be subjects of limitation. Current solution may use IP address filter or access list. This paper proposes subjective properties of users or applications are used for priority determination in multiple access techniques. The NS-2 simulator is employed to evaluate the method. A video surveillance network using WiMAX is chosen as the object. Subjective priority is implemented on WiMAX scheduler based on traffic properties. Three different traffic sources from monitoring video: palace, park, and market are evaluated. The proposed subjective scheduler prioritizes palace monitoring video that results better quality, xx dB than the later monitoring spots.
ERIC Educational Resources Information Center
Soares, Louise M.
1998-01-01
Argues that a unique combination of (1) the Copernican Plan for block scheduling; (2) the application of Howard Gardner's theory of multiple intelligences; and (3) John Dewey's basic ideas about process create a teacher training program in which mastery is an achievable goal. Describes each component and illustrates how each has worked in one…
Memory-Based Structured Application Specific Integrated Circuit (ASIC) Study
2008-10-01
memory interface, arbiter/ schedulers for rescheduling the memory requests according to some schedule policy, and memory channels for communicating...between the power-savings and the wakeup overhead with respect to both wakeup power and wakeup delay. For example, dream mode can save 50% more static...power than sleep mode, but at the expense of twice the wake delay and three times the wakeup energy. The user can specify power-gating modes for various components.
NASA Technical Reports Server (NTRS)
Maxwell, Theresa G.; McNair, Ann R. (Technical Monitor)
2002-01-01
The planning processes for the International Space Station (ISS) Program are quite complex. Detailed mission planning for ISS on-orbit operations is a distributed function. Pieces of the on-orbit plan are developed by multiple planning organizations, located around the world, based on their respective expertise and responsibilities. The "pieces" are then integrated to yield the final detailed plan that will be executed onboard the ISS. Previous space programs have not distributed the planning and scheduling functions to this extent. Major ISS planning organizations are currently located in the United States (at both the NASA Johnson Space Center (JSC) and NASA Marshall Space Flight Center (MSFC)), in Russia, in Europe, and in Japan. Software systems have been developed by each of these planning organizations to support their assigned planning and scheduling functions. Although there is some cooperative development and sharing of key software components, each planning system has been tailored to meet the unique requirements and operational environment of the facility in which it operates. However, all the systems must operate in a coordinated fashion in order to effectively and efficiently produce a single integrated plan of ISS operations, in accordance with the established planning processes. This paper addresses lessons learned during the development of these multiple distributed planning systems, from the perspective of the developer of one of the software systems. The lessons focus on the coordination required to allow the multiple systems to operate together, rather than on the problems associated with the development of any particular system. Included in the paper is a discussion of typical problems faced during the development and coordination process, such as incompatible development schedules, difficulties in defining system interfaces, technical coordination and funding for shared tools, continually evolving planning concepts/requirements, programmatic and budget issues, and external influences. Techniques that mitigated some of these problems will also be addressed, along with recommendations for any future programs involving the development of multiple planning and scheduling systems. Many of these lessons learned are not unique to the area of planning and scheduling systems, so may be applied to other distributed ground systems that must operate in concert to successfully support space mission operations.
NASA Technical Reports Server (NTRS)
Maxwell, Theresa G.
2002-01-01
The planning processes for the International Space Station (ISS) Program are quite complex. Detailed mission planning for ISS on-orbit operations is a distributed function. Pieces of the on-orbit plan are developed by multiple planning organizations, located around the world, based on their respective expertise and responsibilities. The pieces are then integrated to yield the final detailed plan that will be executed onboard the ISS. Previous space programs have not distributed the planning and scheduling functions to this extent. Major ISS planning organizations are currently located in the United States (at both the NASA Johnson Space Center (JSC) and NASA Marshall Space Flight Center (MSFC)), in Russia, in Europe, and in Japan. Software systems have been developed by each of these planning organizations to support their assigned planning and scheduling functions. Although there is some cooperative development and sharing of key software components, each planning system has been tailored to meet the unique requirements and operational environment of the facility in which it operates. However, all the systems must operate in a coordinated fashion in order to effectively and efficiently produce a single integrated plan of ISS operations, in accordance with the established planning processes. This paper addresses lessons learned during the development of these multiple distributed planning systems, from the perspective of the developer of one of the software systems. The lessons focus on the coordination required to allow the multiple systems to operate together, rather than on the problems associated with the development of any particular system. Included in the paper is a discussion of typical problems faced during the development and coordination process, such as incompatible development schedules, difficulties in defining system interfaces, technical coordination and funding for shared tools, continually evolving planning concepts/requirements, programmatic and budget issues, and external influences. Techniques that mitigated some of these problems will also be addressed, along with recommendations for any future programs involving the development of multiple planning and scheduling systems. Many of these lessons learned are not unique to the area of planning and scheduling systems, so may be applied to other distributed ground systems that must operate in concert to successfully support space mission operations.
Fisher, Wayne W.; Greer, Brian D.; Fuhrman, Ashley M.; Querim, Angie C.
2016-01-01
Multiple schedules with signaled periods of reinforcement and extinction have been used to thin reinforcement schedules during functional communication training (FCT) to make the intervention more practical for parents and teachers. We evaluated whether these signals would also facilitate rapid transfer of treatment effects from one setting to the next and from one therapist to the next. With two children, we conducted FCT in the context of mixed (baseline) and multiple (treatment) schedules introduced across settings or therapists using a multiple baseline design. Results indicated that when the multiple schedules were introduced, the functional communication response came under rapid discriminative control, and problem behavior remained at near-zero rates. We extended these findings with another individual by using a more traditional baseline in which problem behavior produced reinforcement. Results replicated those of the previous participants and showed rapid reductions in problem behavior when multiple schedules were implemented across settings. PMID:26384141
Fisher, Wayne W; Greer, Brian D; Fuhrman, Ashley M; Querim, Angie C
2015-12-01
Multiple schedules with signaled periods of reinforcement and extinction have been used to thin reinforcement schedules during functional communication training (FCT) to make the intervention more practical for parents and teachers. We evaluated whether these signals would also facilitate rapid transfer of treatment effects across settings and therapists. With 2 children, we conducted FCT in the context of mixed (baseline) and multiple (treatment) schedules introduced across settings or therapists using a multiple baseline design. Results indicated that when the multiple schedules were introduced, the functional communication response came under rapid discriminative control, and problem behavior remained at near-zero rates. We extended these findings with another individual by using a more traditional baseline in which problem behavior produced reinforcement. Results replicated those of the previous participants and showed rapid reductions in problem behavior when multiple schedules were implemented across settings. © Society for the Experimental Analysis of Behavior.
Medicare physician payment systems: impact of 2011 schedule on interventional pain management.
Manchikanti, Laxmaiah; Singh, Vijay; Caraway, David L; Benyamin, Ramsin M; Hirsch, Joshua A
2011-01-01
Physicians in the United States have been affected by significant changes in the patterns of medical practice evolving over the last several decades. The recently passed affordable health care law, termed the Patient Protection and Affordable Care Act of 2010 (the ACA, for short) affects physicians more than any other law. Physician services are an integral part of health care. Physicians are paid in the United States for their personal services. This payment also includes the overhead expenses for maintaining an office and providing services. The payment system is highly variable in the private insurance market; however, governmental systems have a formula-based payment, mostly based on the Medicare payment system. Physician services are billed under Part B. Since the inception of the Medicare program in 1965, several methods have been used to determine the amounts paid to physicians for each covered service. Initially, the payment systems compensated physicians on the basis of their charges. In 1975, just over 10 years after the inception of the Medicare program, payments changed so as not to exceed the increase in the Medical Economic Index (MEI). Nevertheless, the policy failed to curb increases in costs, leading to the determination of a yearly change in fees by legislation from 1984 to 1991. In 1992, the fee schedule essentially replaced the prior payment system that was based on the physician's charges, which also failed to live up to expectations for operational success. Then, in 1998, the sustainable growth rate (SGR) system was introduced. In 2009, multiple attempts were made by Congress to repeal the formula - rather unsuccessfully. Consequently, the SGR formula continues to hamper physician payments. The mechanism of the SGR includes 3 components that are incorporated into a statutory formula: expenditure targets, growth rate period, and annual adjustments of payment rates for physician services. Further, the relative value of a physician fee schedule is based on 3 components: physician work, practice expense (PE), and malpractice expense that are used to determine a value ranking for each service to which it is applied. On average, the work component represents 53.5% of a service's relative value, the fee component represents 43.6%, and the malpractice component represents 3.9%. The final schedule for physician payment was issued on November 24, 2010. This was based on a total cut of 30.8% with 24.9% of the cut attributed to SGR. However, as usual, with patchwork efficiency, Congress passed a one-year extension of the 0% update, effective through December 2011. Consequently, CMS issued an emergency update of the 2011 Medicare fee schedule, with multiple revisions, resulting in a reduction of the conversion factor of $36.8729 from December 2010 to $33.9764 for 2011.
Multiresource allocation and scheduling for periodic soft real-time applications
NASA Astrophysics Data System (ADS)
Gopalan, Kartik; Chiueh, Tzi-cker
2001-12-01
Real-time applications that utilize multiple system resources, such as CPU, disks, and network links, require coordinated scheduling of these resources in order to meet their end-to-end performance requirements. Most state-of-the-art operating systems support independent resource allocation and deadline-driven scheduling but lack coordination among multiple heterogeneous resources. This paper describes the design and implementation of an Integrated Real-time Resource Scheduler (IRS) that performs coordinated allocation and scheduling of multiple heterogeneous resources on the same machine for periodic soft real-time application. The principal feature of IRS is a heuristic multi-resource allocation algorithm that reserves multiple resources for real-time applications in a manner that can maximize the number of applications admitted into the system in the long run. At run-time, a global scheduler dispatches the tasks of the soft real-time application to individual resource schedulers according to the precedence constraints between tasks. The individual resource schedulers, which could be any deadline based schedulers, can make scheduling decisions locally and yet collectively satisfy a real-time application's performance requirements. The tightness of overall timing guarantees is ultimately determined by the properties of individual resource schedulers. However, IRS maximizes overall system resource utilization efficiency by coordinating deadline assignment across multiple tasks in a soft real-time application.
Sagone, Elisabetta; De Caroli, Maria Elvira; Nima, Ali Al
2017-01-01
Background One important aspect of subjective judgments about one’s well-being (i.e., subjective well-being: life satisfaction, positive affect, and negative affect) is that cultural features, such as, nationality seem to shape cognitive judgments about the “the ideal life.” In this comparative study we examined differences in subjective well-being and psychological well-being between Italian and Swedish adolescents and tested if the relationship between the three constructs of subjective well-being (i.e., satisfaction with life, positive affect, and negative affect) and psychological well-being was moderated by the adolescents’ nationality. Method Italian (n = 255) and Swedish (n = 277) adolescents answered to the Satisfaction with Life Scale, the Positive Affect Negative Affect Schedule, and Ryff’s Scales of Psychological Well-Being. Differences between samples were tested using a Multiple Analysis of Variance. We also conducted a multiple group analysis (Italy and Sweden) using Structural Equation Modelling to investigate the relationship between all three subjective well-being constructs and psychological well-being. Results Italian adolescents scored significantly higher in satisfaction with life than Swedish adolescents. Additionally, across countries, girls scored significantly higher in negative affect than boys. In both countries, all three constructs of subjective well-being were significantly associated to adolescents’ psychological well-being. Nevertheless, while the effect of the relationship between affect and psychological well-being was almost the same across countries, life satisfaction was more strongly related to psychological well-being among Swedish adolescents. Conclusions The present study shows that there are larger variations between these two cultures in the cognitive construct of subjective well-being than in the affective construct. Accordingly, associations between the cognitive component, not the affective component, of subjective well-being and psychological well-being differ between countries as well. PMID:28097069
Garcia, Danilo; Sagone, Elisabetta; De Caroli, Maria Elvira; Nima, Ali Al
2017-01-01
One important aspect of subjective judgments about one's well-being (i.e., subjective well-being: life satisfaction, positive affect, and negative affect) is that cultural features, such as, nationality seem to shape cognitive judgments about the "the ideal life." In this comparative study we examined differences in subjective well-being and psychological well-being between Italian and Swedish adolescents and tested if the relationship between the three constructs of subjective well-being (i.e., satisfaction with life, positive affect, and negative affect) and psychological well-being was moderated by the adolescents' nationality. Italian ( n = 255) and Swedish ( n = 277) adolescents answered to the Satisfaction with Life Scale, the Positive Affect Negative Affect Schedule, and Ryff's Scales of Psychological Well-Being. Differences between samples were tested using a Multiple Analysis of Variance. We also conducted a multiple group analysis (Italy and Sweden) using Structural Equation Modelling to investigate the relationship between all three subjective well-being constructs and psychological well-being. Italian adolescents scored significantly higher in satisfaction with life than Swedish adolescents. Additionally, across countries, girls scored significantly higher in negative affect than boys. In both countries, all three constructs of subjective well-being were significantly associated to adolescents' psychological well-being. Nevertheless, while the effect of the relationship between affect and psychological well-being was almost the same across countries, life satisfaction was more strongly related to psychological well-being among Swedish adolescents. The present study shows that there are larger variations between these two cultures in the cognitive construct of subjective well-being than in the affective construct. Accordingly, associations between the cognitive component, not the affective component, of subjective well-being and psychological well-being differ between countries as well.
Zentall, Thomas R; Singer, Rebecca A
2007-07-01
When behavior suggests that the value of a reinforcer depends inversely on the value of the events that precede or follow it, the behavior has been described as a contrast effect. Three major forms of contrast have been studied: incentive contrast, in which a downward (or upward) shift in the magnitude of reinforcement produces a relatively stronger downward (or upward) shift in the vigor of a response; anticipatory contrast, in which a forthcoming improvement in reinforcement results in a relative reduction in consummatory response; and behavioral contrast, in which a decrease in the probability of reinforcement in one component of a multiple schedule results in an increase in responding in an unchanged component of the schedule. Here we discuss a possible fourth kind of contrast that we call within-trial contrast because within a discrete trial, the relative value of an event has an inverse effect on the relative value of the reinforcer that follows. We show that greater effort, longer delay to reinforcement, or the absence of food all result in an increase in the preference for positive discriminative stimuli that follow (relative to less effort, shorter delay, or the presence of food). We further distinguish this within-trial contrast effect from the effects of delay reduction. A general model of this form of contrast is proposed in which the value of a primary or conditioned reinforcer depends on the change in value from the value of the event that precedes it.
Zentall, Thomas R; Singer, Rebecca A
2007-01-01
When behavior suggests that the value of a reinforcer depends inversely on the value of the events that precede or follow it, the behavior has been described as a contrast effect. Three major forms of contrast have been studied: incentive contrast, in which a downward (or upward) shift in the magnitude of reinforcement produces a relatively stronger downward (or upward) shift in the vigor of a response; anticipatory contrast, in which a forthcoming improvement in reinforcement results in a relative reduction in consummatory response; and behavioral contrast, in which a decrease in the probability of reinforcement in one component of a multiple schedule results in an increase in responding in an unchanged component of the schedule. Here we discuss a possible fourth kind of contrast that we call within-trial contrast because within a discrete trial, the relative value of an event has an inverse effect on the relative value of the reinforcer that follows. We show that greater effort, longer delay to reinforcement, or the absence of food all result in an increase in the preference for positive discriminative stimuli that follow (relative to less effort, shorter delay, or the presence of food). We further distinguish this within-trial contrast effect from the effects of delay reduction. A general model of this form of contrast is proposed in which the value of a primary or conditioned reinforcer depends on the change in value from the value of the event that precedes it. PMID:17725056
Buchvold, Hogne Vikanes; Pallesen, Ståle; Waage, Siri; Bjorvatn, Bjørn
2018-05-01
Objectives The aim of this study was to investigate changes in body mass index (BMI) between different work schedules and different average number of yearly night shifts over a four-year follow-up period. Methods A prospective study of Norwegian nurses (N=2965) with different work schedules was conducted: day only, two-shift rotation (day and evening shifts), three-shift rotation (day, evening and night shifts), night only, those who changed towards night shifts, and those who changed away from schedules containing night shifts. Paired student's t-tests were used to evaluate within subgroup changes in BMI. Multiple linear regression analysis was used to evaluate between groups effects on BMI when adjusting for BMI at baseline, sex, age, marital status, children living at home, and years since graduation. The same regression model was used to evaluate the effect of average number of yearly night shifts on BMI change. Results We found that night workers [mean difference (MD) 1.30 (95% CI 0.70-1.90)], two shift workers [MD 0.48 (95% CI 0.20-0.75)], three shift workers [MD 0.46 (95% CI 0.30-0.62)], and those who changed work schedule away from [MD 0.57 (95% CI 0.17-0.84)] or towards night work [MD 0.63 (95% CI 0.20-1.05)] all had significant BMI gain (P<0.01) during the follow-up period. However, day workers had a non-significant BMI gain. Using adjusted multiple linear regressions, we found that night workers had significantly larger BMI gain compared to day workers [B=0.89 (95% CI 0.06-1.72), P<0.05]. We did not find any significant association between average number of yearly night shifts and BMI change using our multiple linear regression model. Conclusions After adjusting for possible confounders, we found that BMI increased significantly more among night workers compared to day workers.
Influences on Cocaine Tolerance Assessed under a Multiple Conjunctive Schedule of Reinforcement
ERIC Educational Resources Information Center
Yoon, Jin Ho; Branch, Marc N.
2009-01-01
Under multiple schedules of reinforcement, previous research has generally observed tolerance to the rate-decreasing effects of cocaine that has been dependent on schedule-parameter size in the context of fixed-ratio (FR) schedules, but not under the context of fixed-interval (FI) schedules of reinforcement. The current experiment examined the…
Pastrana, Sarah J; Rapp, John T; Frewing, Tyla M
2013-07-01
A number of studies have shown that response interruption and redirection (RIRD) decreases immediate engagement in targeted stereotypic behaviors; however, its effects on untargeted stereotypy have not yet been studied, and its effects following removal of treatment are unclear. We evaluated the immediate and subsequent effects of RIRD on targeted motor stereotypy, as well as untargeted but higher probability vocal stereotypy, of two participants diagnosed with autism, using a three-component multiple-schedule design. Treatment with RIRD decreased immediate engagement in motor stereotypy for both participants, and did not increase subsequent engagement above baseline levels for either participant. In addition, RIRD produced modest changes in immediate engagement in untargeted vocal stereotypy for both participants. We briefly discuss the clinical implications and limitations of the findings from this study.
48 CFR 538.270 - Evaluation of multiple award schedule (MAS) offers.
Code of Federal Regulations, 2010 CFR
2010-10-01
... SERVICES ADMINISTRATION SPECIAL CATEGORIES OF CONTRACTING FEDERAL SUPPLY SCHEDULE CONTRACTING Establishing and Administering Federal Supply Schedules 538.270 Evaluation of multiple award schedule (MAS) offers... determining the Government's price negotiation objectives, consider the following factors: (1) Aggregate...
Second-order schedules: discrimination of components1
Squires, Nancy; Norborg, James; Fantino, Edmund
1975-01-01
Pigeons were exposed to a series of second-order schedules in which the completion of a fixed number of fixed-interval components produced food. In Experiment 1, brief (2 sec) stimulus presentations occurred as each fixed-interval component was completed. During the brief-stimulus presentation terminating the last fixed-interval component, a response was required on a second key, the brief-stimulus key, to produce food. Responses on the brief-stimulus key before the last brief-stimulus presentation had no scheduled consequences, but served as a measure of the extent to which the final component was discriminated from preceding components. Whether there were one, two, four, or eight fixed-interval components, responses on the brief-stimulus key occurred during virtually every brief-stimulus presentation. In Experiment 2, an attempt was made to punish unnecessary responses on the brief-stimulus key, i.e., responses on the brief-stimulus key that occurred before the last component. None of the pigeons learned to withhold these responses, even though they produced a 15-sec timeout and loss of primary reinforcement. In Experiment 3, different key colors were associated with each component of a second-order schedule (a chain schedule). In contrast to Experiment 1, brief-stimulus key responses were confined to the last component. It was concluded that pigeons do not discriminate well between components of second-order schedules unless a unique exteroceptive cue is provided for each component. The relative discriminability of the components may account for the observed differences in initial-component response rates between comparable brief-stimulus, tandem, and chain schedules. PMID:16811868
Science Planning for Multi-Spacecraft Coordinated Observations
NASA Technical Reports Server (NTRS)
Maks, Lori; Fishman, Mark; Pell, Vince; Obenschain, Arthur F. (Technical Monitor)
2002-01-01
Fulfilling the promise of an era of great observatories, NASA now has more than three space-based astronomical telescopes operating in different wavebands. This situation provides astronomers with a unique opportunity to simultaneously observe with multiple observatories. Yet scheduling multiple observatories simultaneously is highly inefficient when compared to single observatory observations. Thus, programs using multiple observatories are limited not due to scientific restrictions, but due to operational inefficiencies. Each year, a number of proposals are accepted by a space-based observatory for conduction of astronomical observations and gathering of science data for the study of galactic events. Since each space-based observatory uses a set of instruments designed to operate in specific energy regions, most such studies are conducted by submitting observation proposals to multiple observatories, with requests to coordinate among themselves. To assure that the proposed observations can be scheduled, each observatory's staff has to check that the observations are valid and meet all the constraints for their own observatory; in addition, they have to verify that the observations satisfy the constraints of the other observatories. Thus, coordinated observations require painstaking manual collaboration among the observatory staff at each observatory. In order to exploit new paradigms for observatory operation, the Goddard Space Flight Center's Advanced Architectures and Automation Branch has developed a prototype tool called the Visual Observation Layout Tool (VOLT). The main objective of VOLT is to provide a visual tool to automate the science planning of coordinated observations for multiple spacecraft, as well as to increase the scheduling probability of observations. However, VOLT is also useful for single observatory planning to optimize observatory control. Three space-based missions are interested in using VOLT (the Hubble Space Telescope, the Chandra X-Ray Observatory, and the Far Ultraviolet Spectroscopic Explorer). The VOLT team members have collaborated with these missions to gather requirements and obtain feedback on their mission planning processes. VOLT has been developed as a cross-platform Java client application for use by scientists and observatory science planning staff to visualize scheduling options and constraints. It also supports a lightweight graphical user interface for remote viewing via a Web front end. Additionally, it uniquely supports the ability to interact with multiple, diverse scheduling packages in order to determine windows of opportunity for observations and visually portray the constraints of each observation request. VOLT enables science data capture scenarios which are currently either impossible, or which require extensive time and manpower to coordinate amongst multiple observatories. it supports early detection of planning conflicts by generating coordinated solutions based on observatory schedulability and constraints. The project development approach has included frequent prototype demonstrations to our interested missions to obtain feedback after each release of the software. We will present an overview of our lessons learned in infusing the VOLT tool into the operations of the missions we have collaborated with and a brief demonstration of the software.
Application of model predictive control for optimal operation of wind turbines
NASA Astrophysics Data System (ADS)
Yuan, Yuan; Cao, Pei; Tang, J.
2017-04-01
For large-scale wind turbines, reducing maintenance cost is a major challenge. Model predictive control (MPC) is a promising approach to deal with multiple conflicting objectives using the weighed sum approach. In this research, model predictive control method is applied to wind turbine to find an optimal balance between multiple objectives, such as the energy capture, loads on turbine components, and the pitch actuator usage. The actuator constraints are integrated into the objective function at the control design stage. The analysis is carried out in both the partial load region and full load region, and the performances are compared with those of a baseline gain scheduling PID controller. The application of this strategy achieves enhanced balance of component loads, the average power and actuator usages in partial load region.
Scheduling time-critical graphics on multiple processors
NASA Technical Reports Server (NTRS)
Meyer, Tom W.; Hughes, John F.
1995-01-01
This paper describes an algorithm for the scheduling of time-critical rendering and computation tasks on single- and multiple-processor architectures, with minimal pipelining. It was developed to manage scientific visualization scenes consisting of hundreds of objects, each of which can be computed and displayed at thousands of possible resolution levels. The algorithm generates the time-critical schedule using progressive-refinement techniques; it always returns a feasible schedule and, when allowed to run to completion, produces a near-optimal schedule which takes advantage of almost the entire multiple-processor system.
Evolutionary Scheduler for the Deep Space Network
NASA Technical Reports Server (NTRS)
Guillaume, Alexandre; Lee, Seungwon; Wang, Yeou-Fang; Zheng, Hua; Chau, Savio; Tung, Yu-Wen; Terrile, Richard J.; Hovden, Robert
2010-01-01
A computer program assists human schedulers in satisfying, to the maximum extent possible, competing demands from multiple spacecraft missions for utilization of the transmitting/receiving Earth stations of NASA s Deep Space Network. The program embodies a concept of optimal scheduling to attain multiple objectives in the presence of multiple constraints.
Service-Oriented Node Scheduling Scheme for Wireless Sensor Networks Using Markov Random Field Model
Cheng, Hongju; Su, Zhihuang; Lloret, Jaime; Chen, Guolong
2014-01-01
Future wireless sensor networks are expected to provide various sensing services and energy efficiency is one of the most important criterions. The node scheduling strategy aims to increase network lifetime by selecting a set of sensor nodes to provide the required sensing services in a periodic manner. In this paper, we are concerned with the service-oriented node scheduling problem to provide multiple sensing services while maximizing the network lifetime. We firstly introduce how to model the data correlation for different services by using Markov Random Field (MRF) model. Secondly, we formulate the service-oriented node scheduling issue into three different problems, namely, the multi-service data denoising problem which aims at minimizing the noise level of sensed data, the representative node selection problem concerning with selecting a number of active nodes while determining the services they provide, and the multi-service node scheduling problem which aims at maximizing the network lifetime. Thirdly, we propose a Multi-service Data Denoising (MDD) algorithm, a novel multi-service Representative node Selection and service Determination (RSD) algorithm, and a novel MRF-based Multi-service Node Scheduling (MMNS) scheme to solve the above three problems respectively. Finally, extensive experiments demonstrate that the proposed scheme efficiently extends the network lifetime. PMID:25384005
CBSD Version 2 Component Models of the IR Celestial Background
1990-12-07
to B1950.0) INCL Inclination of orbit (referred to B1950.0) E Eccentricity SMA Semi-major axis (AU) OBLIQ Obliquity of the ecliptic (at B1950.0) The...pre-release summary of Super Sky Flux: Plates for ecliptic latitudes >500 are scheduled to be available in Spring 1991; full-sky coverage is scheduled...individual HCON Plate sets, a three HCON co-add plate set is being developed; however, regions within ±30’ of the ecliptic plane may not be included in
Principles and Guidelines for Duty and Rest Scheduling in Commercial Aviation
NASA Technical Reports Server (NTRS)
Dinges, David F.; Graeber, R. Curtis; Rosekind, Mark R.; Samel, Alexander
1996-01-01
The aviation industry requires 24-hour activities to meet operational demands. Growth in global long-haul, regional, overnight cargo, and short-haul domestic operations will continue to increase these round-the-clock requirements. Flight crews must be available to support 24-hour-a-day operations to meet these industry demands. Both domestic and international aviation can also require crossing multiple time zones. Therefore, shift work, night work, irregular work schedules, unpredictable work schedules, and dm zone changes will continue to be commonplace components of the aviation industry. These factors pose known challenges to human physiology, and because they result in performance-impairing fatigue, they pose a risk to safety. It is critical to acknowledge and, whenever possible, incorporate scientific information on fatigue, human sleep, and circadian physiology into 24-hour aviation operations. Utilization of such scientific information can help promote crew performance and alertness during flight operations and thereby maintain and improve the safety margin.
A new technology for manufacturing scheduling derived from space system operations
NASA Technical Reports Server (NTRS)
Hornstein, R. S.; Willoughby, J. K.
1993-01-01
A new technology for producing finite capacity schedules has been developed in response to complex requirements for operating space systems such as the Space Shuttle, the Space Station, and the Deep Space Network for telecommunications. This technology has proven its effectiveness in manufacturing environments where popular scheduling techniques associated with Materials Resources Planning (MRPII) and with factory simulation are not adequate for shop-floor work planning and control. The technology has three components. The first is a set of data structures that accommodate an extremely general description of a factory's resources, its manufacturing activities, and the constraints imposed by the environment. The second component is a language and set of software utilities that enable a rapid synthesis of functional capabilities. The third component is an algorithmic architecture called the Five Ruleset Model which accommodates the unique needs of each factory. Using the new technology, systems can model activities that generate, consume, and/or obligate resources. This allows work-in-process (WIP) to be generated and used; it permits constraints to be imposed or intermediate as well as finished goods inventories. It is also possible to match as closely as possible both the current factory state and future conditions such as promise dates. Schedule revisions can be accommodated without impacting the entire production schedule. Applications have been successful in both discrete and process manufacturing environments. The availability of a high-quality finite capacity production planning capability enhances the data management capabilities of MRP II systems. These schedules can be integrated with shop-floor data collection systems and accounting systems. Using the new technology, semi-custom systems can be developed at costs that are comparable to products that do not have equivalent functional capabilities and/or extensibility.
Automation of Coordinated Planning Between Observatories: The Visual Observation Layout Tool (VOLT)
NASA Technical Reports Server (NTRS)
Maks, Lori; Koratkar, Anuradha; Kerbel, Uri; Pell, Vince
2002-01-01
Fulfilling the promise of the era of great observatories, NASA now has more than three space-based astronomical telescopes operating in different wavebands. This situation provides astronomers with the unique opportunity of simultaneously observing a target in multiple wavebands with these observatories. Currently scheduling multiple observatories simultaneously, for coordinated observations, is highly inefficient. Coordinated observations require painstaking manual collaboration among the observatory staff at each observatory. Because they are time-consuming and expensive to schedule, observatories often limit the number of coordinated observations that can be conducted. In order to exploit new paradigms for observatory operation, the Advanced Architectures and Automation Branch of NASA's Goddard Space Flight Center has developed a tool called the Visual Observation Layout Tool (VOLT). The main objective of VOLT is to provide a visual tool to automate the planning of coordinated observations by multiple astronomical observatories. Four of NASA's space-based astronomical observatories - the Hubble Space Telescope (HST), Far Ultraviolet Spectroscopic Explorer (FUSE), Rossi X-ray Timing Explorer (RXTE) and Chandra - are enthusiastically pursuing the use of VOLT. This paper will focus on the purpose for developing VOLT, as well as the lessons learned during the infusion of VOLT into the planning and scheduling operations of these observatories.
NASA Astrophysics Data System (ADS)
Wang, Hongfeng; Fu, Yaping; Huang, Min; Wang, Junwei
2016-03-01
The operation process design is one of the key issues in the manufacturing and service sectors. As a typical operation process, the scheduling with consideration of the deteriorating effect has been widely studied; however, the current literature only studied single function requirement and rarely considered the multiple function requirements which are critical for a real-world scheduling process. In this article, two function requirements are involved in the design of a scheduling process with consideration of the deteriorating effect and then formulated into two objectives of a mathematical programming model. A novel multiobjective evolutionary algorithm is proposed to solve this model with combination of three strategies, i.e. a multiple population scheme, a rule-based local search method and an elitist preserve strategy. To validate the proposed model and algorithm, a series of randomly-generated instances are tested and the experimental results indicate that the model is effective and the proposed algorithm can achieve the satisfactory performance which outperforms the other state-of-the-art multiobjective evolutionary algorithms, such as nondominated sorting genetic algorithm II and multiobjective evolutionary algorithm based on decomposition, on all the test instances.
Short-term scheduling of an open-pit mine with multiple objectives
NASA Astrophysics Data System (ADS)
Blom, Michelle; Pearce, Adrian R.; Stuckey, Peter J.
2017-05-01
This article presents a novel algorithm for the generation of multiple short-term production schedules for an open-pit mine, in which several objectives, of varying priority, characterize the quality of each solution. A short-term schedule selects regions of a mine site, known as 'blocks', to be extracted in each week of a planning horizon (typically spanning 13 weeks). Existing tools for constructing these schedules use greedy heuristics, with little optimization. To construct a single schedule in which infrastructure is sufficiently utilized, with production grades consistently close to a desired target, a planner must often run these heuristics many times, adjusting parameters after each iteration. A planner's intuition and experience can evaluate the relative quality and mineability of different schedules in a way that is difficult to automate. Of interest to a short-term planner is the generation of multiple schedules, extracting available ore and waste in varying sequences, which can then be manually compared. This article presents a tool in which multiple, diverse, short-term schedules are constructed, meeting a range of common objectives without the need for iterative parameter adjustment.
Reinforcer magnitude and rate dependency: evaluation of resistance-to-change mechanisms.
Pinkston, Jonathan W; Ginsburg, Brett C; Lamb, Richard J
2014-10-01
Under many circumstances, reinforcer magnitude appears to modulate the rate-dependent effects of drugs such that when schedules arrange for relatively larger reinforcer magnitudes rate dependency is attenuated compared with behavior maintained by smaller magnitudes. The current literature on resistance to change suggests that increased reinforcer density strengthens operant behavior, and such strengthening effects appear to extend to the temporal control of behavior. As rate dependency may be understood as a loss of temporal control, the effects of reinforcer magnitude on rate dependency may be due to increased resistance to disruption of temporally controlled behavior. In the present experiments, pigeons earned different magnitudes of grain during signaled components of a multiple FI schedule. Three drugs, clonidine, haloperidol, and morphine, were examined. All three decreased overall rates of key pecking; however, only the effects of clonidine were attenuated as reinforcer magnitude increased. An analysis of within-interval performance found rate-dependent effects for clonidine and morphine; however, these effects were not modulated by reinforcer magnitude. In addition, we included prefeeding and extinction conditions, standard tests used to measure resistance to change. In general, rate-decreasing effects of prefeeding and extinction were attenuated by increasing reinforcer magnitudes. Rate-dependent analyses of prefeeding showed rate-dependency following those tests, but in no case were these effects modulated by reinforcer magnitude. The results suggest that a resistance-to-change interpretation of the effects of reinforcer magnitude on rate dependency is not viable.
System cost/performance analysis (study 2.3). Volume 1: Executive summary
NASA Technical Reports Server (NTRS)
Kazangey, T.
1973-01-01
The relationships between performance, safety, cost, and schedule parameters were identified and quantified in support of an overall effort to generate program models and methodology that provide insight into a total space vehicle program. A specific space vehicle system, the attitude control system (ACS), was used, and a modeling methodology was selected that develops a consistent set of quantitative relationships among performance, safety, cost, and schedule, based on the characteristics of the components utilized in candidate mechanisms. These descriptive equations were developed for a three-axis, earth-pointing, mass expulsion ACS. A data base describing typical candidate ACS components was implemented, along with a computer program to perform sample calculations. This approach, implemented on a computer, is capable of determining the effect of a change in functional requirements to the ACS mechanization and the resulting cost and schedule. By a simple extension of this modeling methodology to the other systems in a space vehicle, a complete space vehicle model can be developed. Study results and recommendations are presented.
Exploring Manycore Multinode Systems for Irregular Applications with FPGA Prototyping
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ceriani, Marco; Palermo, Gianluca; Secchi, Simone
We present a prototype of a multi-core architecture implemented on FPGA, designed to enable efficient execution of irregular applications on distributed shared memory machines, while maintaining high performance on regular workloads. The architecture is composed of off-the-shelf soft-core cores, local interconnection and memory interface, integrated with custom components that optimize it for irregular applications. It relies on three key elements: a global address space, multithreading, and fine-grained synchronization. Global addresses are scrambled to reduce the formation of network hot-spots, while the latency of the transactions is covered by integrating an hardware scheduler within the custom load/store buffers to take advantagemore » from the availability of multiple executions threads, increasing the efficiency in a transparent way to the application. We evaluated a dual node system irregular kernels showing scalability in the number of cores and threads.« less
Kern-Dunlap, L; Dunlap, G; Clarke, S; Childs, K E; White, R L; Stewart, M P
1992-01-01
Peer interactions are among the greatest challenges experienced by children who have severe emotional and behavioral problems. This study evaluated an intervention package designed to increase the ratio of these children's desirable to undesirable interactions. The package included three principal components: (a) observation of videotapes following regularly scheduled peer activity sessions; (b) self-evaluation of the children's peer interactions observed on the videotapes; and (c) delayed feedback and reinforcement for desirable peer interactions. Five students from two elementary schools participated. Multiple baseline designs and one reversal were used to evaluate the effects of the intervention package. The results showed that the intervention produced lower levels of undesirable peer interactions and higher ratios of desirable to undesirable interactions for all participants. The results are discussed in regard to their conceptual and applied implications and in terms of specific directions for future research. PMID:1634428
Linear modeling of steady-state behavioral dynamics.
Palya, William L; Walter, Donald; Kessel, Robert; Lucke, Robert
2002-01-01
The observed steady-state behavioral dynamics supported by unsignaled periods of reinforcement within repeating 2,000-s trials were modeled with a linear transfer function. These experiments employed improved schedule forms and analytical methods to improve the precision of the measured transfer function, compared to previous work. The refinements include both the use of multiple reinforcement periods that improve spectral coverage and averaging of independently determined transfer functions. A linear analysis was then used to predict behavior observed for three different test schedules. The fidelity of these predictions was determined. PMID:11831782
NASA Astrophysics Data System (ADS)
Moghaddam, Kamran S.; Usher, John S.
2011-07-01
In this article, a new multi-objective optimization model is developed to determine the optimal preventive maintenance and replacement schedules in a repairable and maintainable multi-component system. In this model, the planning horizon is divided into discrete and equally-sized periods in which three possible actions must be planned for each component, namely maintenance, replacement, or do nothing. The objective is to determine a plan of actions for each component in the system while minimizing the total cost and maximizing overall system reliability simultaneously over the planning horizon. Because of the complexity, combinatorial and highly nonlinear structure of the mathematical model, two metaheuristic solution methods, generational genetic algorithm, and a simulated annealing are applied to tackle the problem. The Pareto optimal solutions that provide good tradeoffs between the total cost and the overall reliability of the system can be obtained by the solution approach. Such a modeling approach should be useful for maintenance planners and engineers tasked with the problem of developing recommended maintenance plans for complex systems of components.
Application of decentralized cooperative problem solving in dynamic flexible scheduling
NASA Astrophysics Data System (ADS)
Guan, Zai-Lin; Lei, Ming; Wu, Bo; Wu, Ya; Yang, Shuzi
1995-08-01
The object of this study is to discuss an intelligent solution to the problem of task-allocation in shop floor scheduling. For this purpose, the technique of distributed artificial intelligence (DAI) is applied. Intelligent agents (IAs) are used to realize decentralized cooperation, and negotiation is realized by using message passing based on the contract net model. Multiple agents, such as manager agents, workcell agents, and workstation agents, make game-like decisions based on multiple criteria evaluations. This procedure of decentralized cooperative problem solving makes local scheduling possible. And by integrating such multiple local schedules, dynamic flexible scheduling for the whole shop floor production can be realized.
Nambe Pueblo Water Budget and Forecasting model.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brainard, James Robert
2009-10-01
This report documents The Nambe Pueblo Water Budget and Water Forecasting model. The model has been constructed using Powersim Studio (PS), a software package designed to investigate complex systems where flows and accumulations are central to the system. Here PS has been used as a platform for modeling various aspects of Nambe Pueblo's current and future water use. The model contains three major components, the Water Forecast Component, Irrigation Scheduling Component, and the Reservoir Model Component. In each of the components, the user can change variables to investigate the impacts of water management scenarios on future water use. The Watermore » Forecast Component includes forecasting for industrial, commercial, and livestock use. Domestic demand is also forecasted based on user specified current population, population growth rates, and per capita water consumption. Irrigation efficiencies are quantified in the Irrigated Agriculture component using critical information concerning diversion rates, acreages, ditch dimensions and seepage rates. Results from this section are used in the Water Demand Forecast, Irrigation Scheduling, and the Reservoir Model components. The Reservoir Component contains two sections, (1) Storage and Inflow Accumulations by Categories and (2) Release, Diversion and Shortages. Results from both sections are derived from the calibrated Nambe Reservoir model where historic, pre-dam or above dam USGS stream flow data is fed into the model and releases are calculated.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rees, D.C.; Wood, R.W.; Laties, V.G.
1984-03-01
The behavioral effects of d-amphetamine have been shown to be modulated by stimulus control, with less impairment of performance occurring when control is great. When the fixed-consecutive-number schedule is used (on which at least a specified consecutive number of responses must be made on one operandum before a single response on another will produce a reinforcer), response rate tends to invariant but reinforcement frequency is not. This study asks whether the differences in reinforcement frequency that usually accompany changes in stimulus control could themselves be responsible for the performance differences. Two versions of the fixed-consecutive-number schedule of reinforcement were combinedmore » into a multiple schedule within which stimulus control was varied but differences in reinforcement frequency were minimized by omitting some reinforcer deliveries during the component that usually had the higher reinforcement frequency. In one component, a compound discriminative stimulus was added with the eighth consecutive response on the first lever, a single response on the second lever was then reinforced. In the other component, no such stimulus was presented. With no added stimulus, large decreases occurred in the number of runs satisfying the minimum requirement for reinforcement at doses of drug that produced only minimal changes when an added stimulus controlled behavior. Thus, increased stimulus control diminishes the behavioral changes produced by d-amphetamine even when the possible contribution by baseline reinforcement rate is minimized. 17 references, 6 figures, 4 tables.« less
Space Tug Docking Study. Volume 5: Cost Analysis
NASA Technical Reports Server (NTRS)
1976-01-01
The cost methodology, summary cost data, resulting cost estimates by Work Breakdown Structure (WBS), technical characteristics data, program funding schedules and the WBS for the costing are discussed. Cost estimates for two tasks of the study are reported. The first, developed cost estimates for design, development, test and evaluation (DDT&E) and theoretical first unit (TFU) at the component level (Level 7) for all items reported in the data base. Task B developed total subsystem DDT&E costs and funding schedules for the three candidate Rendezvous and Docking Systems: manual, autonomous, and hybrid.
An Holistic Approach for Assisting Educationally Underprepared Students.
ERIC Educational Resources Information Center
Greenbaum, Allen
1981-01-01
Describes the Supportive Services Program (SSP) at the University of Minnesota, Duluth, focusing on program objectives and components, the three-stage academic assessment process, the structure of SSP courses, the use of peer assistants, cluster scheduling, advising, and the experiences and reactions of SSP students. (AYC)
Duan, Litian; Wang, Zizhong John; Duan, Fu
2016-11-16
In the multiple-reader environment (MRE) of radio frequency identification (RFID) system, multiple readers are often scheduled to interrogate the randomized tags via operating at different time slots or frequency channels to decrease the signal interferences. Based on this, a Geometric Distribution-based Multiple-reader Scheduling Optimization Algorithm using Artificial Immune System (GD-MRSOA-AIS) is proposed to fairly and optimally schedule the readers operating from the viewpoint of resource allocations. GD-MRSOA-AIS is composed of two parts, where a geometric distribution function combined with the fairness consideration is first introduced to generate the feasible scheduling schemes for reader operation. After that, artificial immune system (including immune clone, immune mutation and immune suppression) quickly optimize these feasible ones as the optimal scheduling scheme to ensure that readers are fairly operating with larger effective interrogation range and lower interferences. Compared with the state-of-the-art algorithm, the simulation results indicate that GD-MRSOA-AIS could efficiently schedules the multiple readers operating with a fairer resource allocation scheme, performing in larger effective interrogation range.
Duan, Litian; Wang, Zizhong John; Duan, Fu
2016-01-01
In the multiple-reader environment (MRE) of radio frequency identification (RFID) system, multiple readers are often scheduled to interrogate the randomized tags via operating at different time slots or frequency channels to decrease the signal interferences. Based on this, a Geometric Distribution-based Multiple-reader Scheduling Optimization Algorithm using Artificial Immune System (GD-MRSOA-AIS) is proposed to fairly and optimally schedule the readers operating from the viewpoint of resource allocations. GD-MRSOA-AIS is composed of two parts, where a geometric distribution function combined with the fairness consideration is first introduced to generate the feasible scheduling schemes for reader operation. After that, artificial immune system (including immune clone, immune mutation and immune suppression) quickly optimize these feasible ones as the optimal scheduling scheme to ensure that readers are fairly operating with larger effective interrogation range and lower interferences. Compared with the state-of-the-art algorithm, the simulation results indicate that GD-MRSOA-AIS could efficiently schedules the multiple readers operating with a fairer resource allocation scheme, performing in larger effective interrogation range. PMID:27854342
NASA Astrophysics Data System (ADS)
Witantyo; Rindiyah, Anita
2018-03-01
According to data from maintenance planning and control, it was obtained that highest inventory value is non-routine components. Maintenance components are components which procured based on maintenance activities. The problem happens because there is no synchronization between maintenance activities and the components required. Reliability Centered Maintenance method is used to overcome the problem by reevaluating maintenance activities required components. The case chosen is roller mill system because it has the highest unscheduled downtime record. Components required for each maintenance activities will be determined by its failure distribution, so the number of components needed could be predicted. Moreover, those components will be reclassified from routine component to be non-routine component, so the procurement could be carried out regularly. Based on the conducted analysis, failure happens in almost every maintenance task are classified to become scheduled on condition task, scheduled discard task, schedule restoration task and no schedule maintenance. From 87 used components for maintenance activities are evaluated and there 19 components that experience reclassification from non-routine components to routine components. Then the reliability and need of those components were calculated for one-year operation period. Based on this invention, it is suggested to change all of the components in overhaul activity to increase the reliability of roller mill system. Besides, the inventory system should follow maintenance schedule and the number of required components in maintenance activity so the value of procurement will be decreased and the reliability system will increase.
Artificial intelligence for the CTA Observatory scheduler
NASA Astrophysics Data System (ADS)
Colomé, Josep; Colomer, Pau; Campreciós, Jordi; Coiffard, Thierry; de Oña, Emma; Pedaletti, Giovanna; Torres, Diego F.; Garcia-Piquer, Alvaro
2014-08-01
The Cherenkov Telescope Array (CTA) project will be the next generation ground-based very high energy gamma-ray instrument. The success of the precursor projects (i.e., HESS, MAGIC, VERITAS) motivated the construction of this large infrastructure that is included in the roadmap of the ESFRI projects since 2008. CTA is planned to start the construction phase in 2015 and will consist of two arrays of Cherenkov telescopes operated as a proposal-driven open observatory. Two sites are foreseen at the southern and northern hemispheres. The CTA observatory will handle several observation modes and will have to operate tens of telescopes with a highly efficient and reliable control. Thus, the CTA planning tool is a key element in the control layer for the optimization of the observatory time. The main purpose of the scheduler for CTA is the allocation of multiple tasks to one single array or to multiple sub-arrays of telescopes, while maximizing the scientific return of the facility and minimizing the operational costs. The scheduler considers long- and short-term varying conditions to optimize the prioritization of tasks. A short-term scheduler provides the system with the capability to adapt, in almost real-time, the selected task to the varying execution constraints (i.e., Targets of Opportunity, health or status of the system components, environment conditions). The scheduling procedure ensures that long-term planning decisions are correctly transferred to the short-term prioritization process for a suitable selection of the next task to execute on the array. In this contribution we present the constraints to CTA task scheduling that helped classifying it as a Flexible Job-Shop Problem case and finding its optimal solution based on Artificial Intelligence techniques. We describe the scheduler prototype that uses a Guarded Discrete Stochastic Neural Network (GDSN), for an easy representation of the possible long- and short-term planning solutions, and Constraint Propagation techniques. A simulation platform, an analysis tool and different test case scenarios for CTA were developed to test the performance of the scheduler and are also described.
SMEX-Lite Modular Solar Array Architecture
NASA Technical Reports Server (NTRS)
Lyons, John W.; Day, John (Technical Monitor)
2002-01-01
The NASA Small Explorer (SMEX) missions have typically had three years between mission definition and launch. This short schedule has posed significant challenges with respect to solar array design and procurement. Typically, the solar panel geometry is frozen prior to going out with a procurement. However, with the SMEX schedule, it has been virtually impossible to freeze the geometry in time to avoid scheduling problems with integrating the solar panels to the spacecraft. A modular solar array architecture was developed to alleviate this problem. This approach involves procuring sufficient modules for multiple missions and assembling the modules onto a solar array framework that is unique to each mission. The modular approach removes the solar array from the critical path of the SMEX integration and testing schedule. It also reduces the cost per unit area of the solar arrays and facilitates the inclusion of experiments involving new solar cell or panel technologies in the SMEX missions.
Increasing Trends in Schedule II Opioid Use and Doctor Shopping during 1999–2007 in California
Han, Huijun; Kass, Philip H.; Wilsey, Barth L.; Li, Chin-Shang
2013-01-01
Purpose To examine the age and gender-specific trends of schedule II opioid use among California residents, with special reference to multiple provider users (“doctor shoppers”). Methods Utilizing data from the California Prescription Drug Monitoring Program, we examined age and gender-specific trends of Schedule II opioid use during calendar years 1999–2007. Specifically, we analyzed: 1) the prevalence of Schedule II opioid users among California’s population, and 2) the proportion of these opioid users who were doctor shoppers (defined as an individual who used more than five different prescribers for all schedule II opioids he/she obtained in a calendar year). Results Among all age and gender groups, the prevalence of Schedule II opioid users in California increased by 150%–280% and the prevalence of doctor shoppers among users increased by 111%–213% over nine years. The prevalence of opioid users was lowest among 18–44 year-old males (1.25%) and highest among 65 years and older females (5.31%) by 2007. The prevalence of doctor shoppers was approximately 1.4% among those up to age 64 and 0.5% among those 65 years and older. The gender difference in doctor shoppers among all age groups was negligible. On average, the cumulative morphine-equivalent amount of Schedule II opioid per individual obtained per year was three- to six-fold higher for doctor shoppers than for the general population across different age and gender groups. Conclusions Age and gender differences in opioid use were relatively small, while the trends for use of opioids and multiple providers grew at a disquieting rate. PMID:23956137
A multi-group and preemptable scheduling of cloud resource based on HTCondor
NASA Astrophysics Data System (ADS)
Jiang, Xiaowei; Zou, Jiaheng; Cheng, Yaodong; Shi, Jingyan
2017-10-01
Due to the features of virtual machine-flexibility, easy controlling and various system environments, more and more fields utilize the virtualization technology to construct the distributed system with the virtual resources, also including high energy physics. This paper introduce a method used in high energy physics that supports multiple resource group and preemptable cloud resource scheduling, combining virtual machine with HTCondor (a batch system). It makes resource controlling more flexible and more efficient and makes resource scheduling independent of job scheduling. Firstly, the resources belong to different experiment-groups, and the type of user-groups mapping to resource-groups(same as experiment-group) is one-to-one or many-to-one. In order to make the confused group simply to be managed, we designed the permission controlling component to ensure that the different resource-groups can get the suitable jobs. Secondly, for the purpose of elastically allocating resources for suitable resource-group, it is necessary to schedule resources like scheduling jobs. So this paper designs the cloud resource scheduling to maintain a resource queue and allocate an appropriate amount of virtual resources to the request resource-group. Thirdly, in some kind of situations, because of the resource occupied for a long time, resources need to be preempted. This paper adds the preemption function for the resource scheduling that implement resource preemption based on the group priority. Additionally, the way to preempting is soft that when virtual resources are preempted, jobs will not be killed but also be held and rematched later. It is implemented with the help of HTCondor, storing the held job information in scheduler, releasing the job to idle status and doing second matcher. In IHEP (institute of high energy physics), we have built a batch system based on HTCondor with a virtual resources pool based on Openstack. And this paper will show some cases of experiment JUNO and LHAASO. The result indicates that multi-group and preemptable resource scheduling is efficient to support multi-group and soft preemption. Additionally, the permission controlling component has been used in the local computing cluster, supporting for experiment JUNO, CMS and LHAASO, and the scale will be expanded to more experiments at the first half year, including DYW, BES and so on. Its evidence that the permission controlling is efficient.
System and method for optimal load and source scheduling in context aware homes
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shetty, Pradeep; Foslien Graber, Wendy; Mangsuli, Purnaprajna R.
A controller for controlling energy consumption in a home includes a constraints engine to define variables for multiple appliances in the home corresponding to various home modes and persona of an occupant of the home. A modeling engine models multiple paths of energy utilization of the multiple appliances to place the home into a desired state from a current context. An optimal scheduler receives the multiple paths of energy utilization and generates a schedule as a function of the multiple paths and a selected persona to place the home in a desired state.
Value of information of repair times for offshore wind farm maintenance planning
NASA Astrophysics Data System (ADS)
Seyr, Helene; Muskulus, Michael
2016-09-01
A large contribution to the total cost of energy in offshore wind farms is due to maintenance costs. In recent years research has focused therefore on lowering the maintenance costs using different approaches. Decision support models for scheduling the maintenance exist already, dealing with different factors influencing the scheduling. Our contribution deals with the uncertainty in the repair times. Given the mean repair times for different turbine components we make some assumptions regarding the underlying repair time distribution. We compare the results of a decision support model for the mean times to repair and those repair time distributions. Additionally, distributions with the same mean but different variances are compared under the same conditions. The value of lowering the uncertainty in the repair time is calculated and we find that using distributions significantly decreases the availability, when scheduling maintenance for multiple turbines in a wind park. Having detailed information about the repair time distribution may influence the results of maintenance modeling and might help identify cost factors.
Íbias, Javier; Pellón, Ricardo; Sanabria, Federico
2014-01-01
Recent research has suggested that frequent short bursts of activity characterize hyperactivity associated with attention deficit hyperactivity disorder (ADHD). This study determined whether such pattern is also visible in schedule-induced polydipsia (SIP) in the spontaneously hypertensive rat (SHR), an animal model of ADHD. Male SHR, Wistar Kyoto (WKY) and Wistar rats were exposed to 40 sessions of SIP using a multiple fixed-time (FT) schedule of food delivery with FT 30-s and FT 90-s components. Stable performance was analysed to determine the extent to which SIP-associated drinking is organized in bouts. The Bi-Exponential Refractory Model (BERM) of free-operant performance was applied to schedule-induced licks. A model comparison analysis supported BERM as a description of SIP episodes: licks were not produced at a constant rate but organized into bouts within drinking episodes. FT 30-s induced similar overall licking rates, latencies to first licks and episode durations across strains; FT 90-s induced longer episode durations in SHRs and reduced licking rate in WKY and Wistar rats to nearly baseline levels. Across schedules, SHRs made more and shorter bouts when compared to the other strains. These results suggest an incentive-induced hyperactivity in SHR that has been observed in operant behavior and in children with ADHD. PMID:25447297
Future aircraft networks and schedules
NASA Astrophysics Data System (ADS)
Shu, Yan
2011-07-01
Because of the importance of air transportation scheduling, the emergence of small aircraft and the vision of future fuel-efficient aircraft, this thesis has focused on the study of aircraft scheduling and network design involving multiple types of aircraft and flight services. It develops models and solution algorithms for the schedule design problem and analyzes the computational results. First, based on the current development of small aircraft and on-demand flight services, this thesis expands a business model for integrating on-demand flight services with the traditional scheduled flight services. This thesis proposes a three-step approach to the design of aircraft schedules and networks from scratch under the model. In the first step, both a frequency assignment model for scheduled flights that incorporates a passenger path choice model and a frequency assignment model for on-demand flights that incorporates a passenger mode choice model are created. In the second step, a rough fleet assignment model that determines a set of flight legs, each of which is assigned an aircraft type and a rough departure time is constructed. In the third step, a timetable model that determines an exact departure time for each flight leg is developed. Based on the models proposed in the three steps, this thesis creates schedule design instances that involve almost all the major airports and markets in the United States. The instances of the frequency assignment model created in this thesis are large-scale non-convex mixed-integer programming problems, and this dissertation develops an overall network structure and proposes iterative algorithms for solving these instances. The instances of both the rough fleet assignment model and the timetable model created in this thesis are large-scale mixed-integer programming problems, and this dissertation develops subproblem schemes for solving these instances. Based on these solution algorithms, this dissertation also presents computational results of these large-scale instances. To validate the models and solution algorithms developed, this thesis also compares the daily flight schedules that it designs with the schedules of the existing airlines. Furthermore, it creates instances that represent different economic and fuel-prices conditions and derives schedules under these different conditions. In addition, it discusses the implication of using new aircraft in the future flight schedules. Finally, future research in three areas---model, computational method, and simulation for validation---is proposed.
NASA Technical Reports Server (NTRS)
Steele, John; Rector, tony; Gazda, Daniel; Lewis, John
2009-01-01
An EMU water processing kit (Airlock Coolant Loop Recovery A/L CLR) was developed as a corrective action to Extravehicular Mobility Unit (EMU) coolant flow disruptions experienced on the International Space Station (ISS) in May of 2004 and thereafter. Conservative schedules for A/L CLR use and component life were initially developed and implemented based on prior analysis results and analytical modeling. The examination of postflight samples and EMU hardware in November of 2006 indicated that the A/L CLR kits were functioning well and had excess capacity that would allow a relaxation of the initially conservative schedules of use and component life. A relaxed use schedule and list of component lives was implemented thereafter. Since the adoption of the relaxed A/L CLR schedules of use and component lives, several A/L CLR kit components, transport loop water samples and sensitive EMU transport loop components have been examined to gage the impact of the relaxed requirements. The intent of this paper is to summarize the findings of that evaluation, and to outline updated schedules for A/L CLR use and component life.
Mota, Natalie; Cox, Brian J; Enns, Murray W; Calhoun, Laura; Sareen, Jitender
2008-08-01
The present study examined health-related quality of life (HRQOL) and the prevalence of mental disorders in pregnant and past-year pregnant women compared to non-pregnant women. Data came from the National Epidemiologic Survey on Alcohol and Related Conditions. Three groups of women (ages 18-44) were compared: currently pregnant (n=451), past-year pregnant (n=1061), and not pregnant (n=10,544). Past-year mood, anxiety and substance use disorders were assessed by the Alcohol Use Disorder and Associated Disabilities Interview Schedule-DSM-IV version. HRQOL was measured by the Medical Outcomes Study Short Form (SF-12). All analyses included sociodemographics as covariates. Multiple logistic regression analyses showed that pregnant women were less likely than non-pregnant women to have depression and alcohol abuse or dependence; and less likely than past-year pregnant women to have depression and mania. Past-year pregnant women were less likely than non-pregnant women to have social phobia and alcohol dependence or abuse. Multiple linear regression analyses demonstrated that pregnant and non-pregnant women had higher mental component scores than past-year pregnant women. Physical component scores were lower in pregnant women than in non-pregnant and past-year pregnant groups. This was a cross-sectional survey and the causality of relationships cannot be inferred. Results suggest that pregnant women have a lower likelihood of mental disorder than both non-pregnant and past-year pregnant women.
Space Station Furnace Facility. Volume 3: Program cost estimate
NASA Technical Reports Server (NTRS)
1992-01-01
The approach used to estimate costs for the Space Station Furnace Facility (SSFF) is based on a computer program developed internally at Teledyne Brown Engineering (TBE). The program produces time-phased estimates of cost elements for each hardware component, based on experience with similar components. Engineering estimates of the degree of similarity or difference between the current project and the historical data is then used to adjust the computer-produced cost estimate and to fit it to the current project Work Breakdown Structure (WBS). The SSFF Concept as presented at the Requirements Definition Review (RDR) was used as the base configuration for the cost estimate. This program incorporates data on costs of previous projects and the allocation of those costs to the components of one of three, time-phased, generic WBS's. Input consists of a list of similar components for which cost data exist, number of interfaces with their type and complexity, identification of the extent to which previous designs are applicable, and programmatic data concerning schedules and miscellaneous data (travel, off-site assignments). Output is program cost in labor hours and material dollars, for each component, broken down by generic WBS task and program schedule phase.
Influencing Trust for Human-Automation Collaborative Scheduling of Multiple Unmanned Vehicles.
Clare, Andrew S; Cummings, Mary L; Repenning, Nelson P
2015-11-01
We examined the impact of priming on operator trust and system performance when supervising a decentralized network of heterogeneous unmanned vehicles (UVs). Advances in autonomy have enabled a future vision of single-operator control of multiple heterogeneous UVs. Real-time scheduling for multiple UVs in uncertain environments requires the computational ability of optimization algorithms combined with the judgment and adaptability of human supervisors. Because of system and environmental uncertainty, appropriate operator trust will be instrumental to maintain high system performance and prevent cognitive overload. Three groups of operators experienced different levels of trust priming prior to conducting simulated missions in an existing, multiple-UV simulation environment. Participants who play computer and video games frequently were found to have a higher propensity to overtrust automation. By priming gamers to lower their initial trust to a more appropriate level, system performance was improved by 10% as compared to gamers who were primed to have higher trust in the automation. Priming was successful at adjusting the operator's initial and dynamic trust in the automated scheduling algorithm, which had a substantial impact on system performance. These results have important implications for personnel selection and training for futuristic multi-UV systems under human supervision. Although gamers may bring valuable skills, they may also be potentially prone to automation bias. Priming during training and regular priming throughout missions may be one potential method for overcoming this propensity to overtrust automation. © 2015, Human Factors and Ergonomics Society.
Tools for Coordinated Planning Between Observatories
NASA Technical Reports Server (NTRS)
Jones, Jeremy; Fishman, Mark; Grella, Vince; Kerbel, Uri; Maks, Lori; Misra, Dharitri; Pell, Vince; Powers, Edward I. (Technical Monitor)
2001-01-01
With the realization of NASA's era of great observatories, there are now more than three space-based telescopes operating in different wavebands. This situation provides astronomers with a unique opportunity to simultaneously observe with multiple observatories. Yet scheduling multiple observatories simultaneously is highly inefficient when compared to observations using only one single observatory. Thus, programs using multiple observatories are limited not due to scientific restrictions, but due to operational inefficiencies. At present, multi-observatory programs are conducted by submitting observing proposals separately to each concerned observatory. To assure that the proposed observations can be scheduled, each observatory's staff has to check that the observations are valid and meet all the constraints for their own observatory; in addition, they have to verify that the observations satisfy the constraints of the other observatories. Thus, coordinated observations require painstaking manual collaboration among the observatory staff at each observatory. Due to the lack of automated tools for coordinated observations, this process is time consuming, error-prone, and the outcome of the requests is not certain until the very end. To increase observatory operations efficiency, such manpower intensive processes need to undergo re-engineering. To overcome this critical deficiency, Goddard Space Flight Center's Advanced Architectures and Automation Branch is developing a prototype effort called the Visual Observation Layout Tool (VOLT). The main objective of the VOLT project is to provide visual tools to help automate the planning of coordinated observations by multiple astronomical observatories, as well as to increase the scheduling probability of all observations.
ERIC Educational Resources Information Center
Fisher, Wayne W.; Greer, Brian D.; Fuhrman, Ashley M.; Querim, Angie C.
2015-01-01
Multiple schedules with signaled periods of reinforcement and extinction have been used to thin reinforcement schedules during functional communication training (FCT) to make the intervention more practical for parents and teachers. We evaluated whether these signals would also facilitate rapid transfer of treatment effects across settings and…
Secure, web-accessible call rosters for academic radiology departments.
Nguyen, A V; Tellis, W M; Avrin, D E
2000-05-01
Traditionally, radiology department call rosters have been posted via paper and bulletin boards. Frequently, changes to these lists are made by multiple people independently, but often not synchronized, resulting in confusion among the house staff and technical staff as to who is on call and when. In addition, multiple and disparate copies exist in different sections of the department, and changes made would not be propagated to all the schedules. To eliminate such difficulties, a paperless call scheduling application was developed. Our call scheduling program allowed Java-enabled web access to a database by designated personnel from each radiology section who have privileges to make the necessary changes. Once a person made a change, everyone accessing the database would see the modification. This eliminates the chaos resulting from people swapping shifts at the last minute and not having the time to record or broadcast the change. Furthermore, all changes to the database were logged. Users are given a log-in name and password and can only edit their section; however, all personnel have access to all sections' schedules. Our applet was written in Java 2 using the latest technology in database access. We access our Interbase database through the DataExpress and DB Swing (Borland, Scotts Valley, CA) components. The result is secure access to the call rosters via the web. There are many advantages to the web-enabled access, mainly the ability for people to make changes and have the changes recorded and propagated in a single virtual location and available to all who need to know.
Temporal Context in Concurrent Chains: I. Terminal-Link Duration
ERIC Educational Resources Information Center
Grace, Randolph C.
2004-01-01
Two experiments are reported in which the ratio of the average times spent in the terminal and initial links ("Tt/Ti") in concurrent chains was varied. In Experiment 1, pigeons responded in a three-component procedure in which terminal-link variable-interval schedules were in constant ratio, but their average duration increased across components…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-17
...-0001; Sequence 21] General Services Administration Acquisition Regulation: Modifications (Multiple... Modifications (Multiple Award Schedule). DATES: Submit comments on or before: February 15, 2013. FOR FURTHER INFORMATION CONTACT: Ms. Dana Munson, General Services Acquisition Policy Division, GSA, (202) 357-9652 or...
Hulin, Mary W; Lawrence, Michelle N; Amato, Russell J; Weed, Peter F; Winsauer, Peter J
2015-03-01
The present study compared two putative pharmacotherapies for alcohol abuse and dependence, dehydroepiandrosterone (DHEA) and pregnanolone, with two Food and Drug Administration (FDA)-approved pharmacotherapies, naltrexone and acamprosate. Experiment 1 assessed the effects of different doses of DHEA, pregnanolone, naltrexone, and acamprosate on both ethanol- and food-maintained responding under a multiple fixed-ratio (FR)-10 FR-20 schedule, respectively. Experiment 2 assessed the effects of different mean intervals of food presentation on responding for ethanol under a FR-10 variable-interval (VI) schedule, whereas Experiment 3 assessed the effects of a single dose of each drug under a FR-10 VI-80 schedule. In Experiment 1, all four drugs dose-dependently decreased response rate for both food and ethanol, although differences in the rate-decreasing effects were apparent among the drugs. DHEA and pregnanolone decreased ethanol-maintained responding more potently than food-maintained responding, whereas the reverse was true for naltrexone. Acamprosate decreased responding for both reinforcers with equal potency. In Experiment 2, different mean intervals of food presentation significantly affected the number of food reinforcers obtained per session; however, changes in the number of food reinforcements did not significantly affect responding for ethanol. Under the FR-10 VI-80 schedule in Experiment 3, only naltrexone significantly decreased both the dose of alcohol presented and blood ethanol concentration (BEC). Acamprosate and pregnanolone had no significant effects on any of the dependent measures, whereas DHEA significantly decreased BEC, but did not significantly decrease response rate or the dose presented. In summary, DHEA and pregnanolone decreased ethanol-maintained responding more potently than food-maintained responding under a multiple FR-10 FR-20 schedule, and were more selective for decreasing ethanol self-administration than either naltrexone or acamprosate under that schedule. Experiment 2 showed that ethanol intake was relatively independent of the interval of reinforcement in the food-maintained component, and Experiment 3 showed that naltrexone was the most effective drug at the doses tested when the interval for food reinforcement was low and maintained under a variable-interval schedule. Copyright © 2015 Elsevier Inc. All rights reserved.
Hulin, Mary W.; Lawrence, Michelle N.; Amato, Russell J.; Weed, Peter F.; Winsauer, Peter J.
2015-01-01
The present study compared two putative pharmacotherapies for alcohol abuse and dependence, dehydroepiandrosterone (DHEA) and pregnanolone, with two Food and Drug Administration (FDA)-approved pharmacotherapies, naltrexone and acamprosate. Experiment 1 assessed the effects of different doses of DHEA, pregnanolone, naltrexone, and acamprosate on both ethanol- and food-maintained responding under a multiple fixed-ratio (FR)-10 FR-20 schedule, respectively. Experiment 2 assessed the effects of different mean intervals of food presentation on responding for ethanol under an FR-10 variable-interval (VI) schedule, whereas Experiment 3 assessed the effects of a single dose of each drug under a FR-10 VI-80 schedule. In Experiment 1, all four drugs dose-dependently decreased response rate for both food and ethanol, although differences in the rate-decreasing effects were apparent among the drugs. DHEA and pregnanolone decreased ethanol-maintained responding more potently than food-maintained responding, whereas the reverse was true for naltrexone. Acamprosate decreased responding for both reinforcers with equal potency. In Experiment 2, different mean intervals of food presentation significantly affected the number of food reinforcers obtained per session; however, changes in the number of food reinforcements did not significantly affect responding for ethanol. Under the FR-10 VI-80 schedule in Experiment 3, only naltrexone significantly decreased both the dose of alcohol presented and blood ethanol concentration (BEC). Acamprosate and pregnanolone had no significant effects on any of the dependent measures, whereas DHEA significantly decreased BEC, but did not significantly decrease response rate or the dose presented. In summary, DHEA and pregnanolone decreased ethanol-maintained responding more potently than food-maintained responding under a multiple FR-10 FR-20 schedule, and were more selective for decreasing ethanol self-administration than either naltrexone or acamprosate under that schedule. Experiment 2 showed that ethanol intake was relatively independent of the density of reinforcement in the food-maintained component, and Experiment 3 showed that naltrexone was the most effective drug at the doses tested when the density for food reinforcement was low and maintained under a variable-interval schedule. PMID:25620274
Refurbishment and Automation of Thermal Vacuum Facilities at NASA/GSFC
NASA Technical Reports Server (NTRS)
Dunn, Jamie; Gomez, Carlos; Donohue, John; Johnson, Chris; Palmer, John; Sushon, Janet
1999-01-01
The thermal vacuum facilities located at the Goddard Space Flight Center (GSFC) have supported both manned and unmanned space flight since the 1960s. Of the eleven facilities, currently ten of the systems are scheduled for refurbishment or replacement as part of a five-year implementation. Expected return on investment includes the reduction in test schedules, improvements in safety of facility operations, and reduction in the personnel support required for a test. Additionally, GSFC will become a global resource renowned for expertise in thermal engineering, mechanical engineering, and for the automation of thermal vacuum facilities and tests. Automation of the thermal vacuum facilities includes the utilization of Programmable Logic Controllers (PLCs), the use of Supervisory Control and Data Acquisition (SCADA) systems, and the development of a centralized Test Data Management System. These components allow the computer control and automation of mechanical components such as valves and pumps. The project of refurbishment and automation began in 1996 and has resulted in complete computer control of one facility (Facility 281), and the integration of electronically controlled devices and PLCs in multiple others.
Refurbishment and Automation of Thermal Vacuum Facilities at NASA/GSFC
NASA Technical Reports Server (NTRS)
Dunn, Jamie; Gomez, Carlos; Donohue, John; Johnson, Chris; Palmer, John; Sushon, Janet
1998-01-01
The thermal vacuum facilities located at the Goddard Space Flight Center (GSFC) have supported both manned and unmanned space flight since the 1960s. Of the eleven facilities, currently ten of the systems are scheduled for refurbishment or replacement as part of a five-year implementation. Expected return on investment includes the reduction in test schedules, improvements in safety of facility operations, and reduction in the personnel support required for a test. Additionally, GSFC will become a global resource renowned for expertise in thermal engineering, mechanical engineering, and for the automation of thermal vacuum facilities and tests. Automation of the thermal vacuum facilities includes the utilization of Programmable Logic Controllers (PLCs), the use of Supervisory Control and Data Acquisition (SCADA) systems, and the development of a centralized Test Data Management System. These components allow the computer control and automation of mechanical components such as valves and pumps. The project of refurbishment and automation began in 1996 and has resulted in complete computer control of one facility (Facility 281), and the integration of electronically controlled devices and PLCs in multiple others.
Human Research Initiative (HRI)
NASA Technical Reports Server (NTRS)
Motil, Brian
2003-01-01
A code U initiative starting in the FY04 budget includes specific funding for 'Phase Change' and 'Multiphase Flow Research' on the ISS. NASA GRC developed a concept for two facilities based on funding/schedule constraints: 1) Two Phase Flow Facility (TphiFFy) which assumes integrating into FIR; 2) Contact Line Dynamics Experiment Facility (CLiDE) which assumes integration into MSG. Each facility will accommodate multiple experiments conducted by NRA selected PIs with an overall goal of enabling specific NASA strategic objectives. There may also be a significant ground-based component.
Web-Based Distributed Simulation of Aeronautical Propulsion System
NASA Technical Reports Server (NTRS)
Zheng, Desheng; Follen, Gregory J.; Pavlik, William R.; Kim, Chan M.; Liu, Xianyou; Blaser, Tammy M.; Lopez, Isaac
2001-01-01
An application was developed to allow users to run and view the Numerical Propulsion System Simulation (NPSS) engine simulations from web browsers. Simulations were performed on multiple INFORMATION POWER GRID (IPG) test beds. The Common Object Request Broker Architecture (CORBA) was used for brokering data exchange among machines and IPG/Globus for job scheduling and remote process invocation. Web server scripting was performed by JavaServer Pages (JSP). This application has proven to be an effective and efficient way to couple heterogeneous distributed components.
A Baseline Load Schedule for the Manual Calibration of a Force Balance
NASA Technical Reports Server (NTRS)
Ulbrich, N.; Gisler, R.
2013-01-01
A baseline load schedule for the manual calibration of a force balance was developed that takes current capabilities at the NASA Ames Balance Calibration Laboratory into account. The load schedule consists of 18 load series with a total of 194 data points. It was designed to satisfy six requirements: (i) positive and negative loadings should be applied for each load component; (ii) at least three loadings should be applied between 0 % and 100 % load capacity; (iii) normal and side force loadings should be applied at the forward gage location, the aft gage location, and the balance moment center; (iv) the balance should be used in UP and DOWN orientation to get axial force loadings; (v) the constant normal and side force approaches should be used to get the rolling moment loadings; (vi) rolling moment loadings should be obtained for 0, 90, 180, and 270 degrees balance orientation. Three different approaches are also reviewed that may be used to independently estimate the natural zeros of the balance. These three approaches provide gage output differences that may be used to estimate the weight of both the metric and non-metric part of the balance. Manual calibration data of NASA s MK29A balance and machine calibration data of NASA s MC60D balance are used to illustrate and evaluate different aspects of the proposed baseline load schedule design.
Multiple-component covalent organic frameworks
Huang, Ning; Zhai, Lipeng; Coupry, Damien E.; Addicoat, Matthew A.; Okushita, Keiko; Nishimura, Katsuyuki; Heine, Thomas; Jiang, Donglin
2016-01-01
Covalent organic frameworks are a class of crystalline porous polymers that integrate molecular building blocks into periodic structures and are usually synthesized using two-component [1+1] condensation systems comprised of one knot and one linker. Here we report a general strategy based on multiple-component [1+2] and [1+3] condensation systems that enable the use of one knot and two or three linker units for the synthesis of hexagonal and tetragonal multiple-component covalent organic frameworks. Unlike two-component systems, multiple-component covalent organic frameworks feature asymmetric tiling of organic units into anisotropic skeletons and unusually shaped pores. This strategy not only expands the structural complexity of skeletons and pores but also greatly enhances their structural diversity. This synthetic platform is also widely applicable to multiple-component electron donor–acceptor systems, which lead to electronic properties that are not simply linear summations of those of the conventional [1+1] counterparts. PMID:27460607
Multiple-component covalent organic frameworks
NASA Astrophysics Data System (ADS)
Huang, Ning; Zhai, Lipeng; Coupry, Damien E.; Addicoat, Matthew A.; Okushita, Keiko; Nishimura, Katsuyuki; Heine, Thomas; Jiang, Donglin
2016-07-01
Covalent organic frameworks are a class of crystalline porous polymers that integrate molecular building blocks into periodic structures and are usually synthesized using two-component [1+1] condensation systems comprised of one knot and one linker. Here we report a general strategy based on multiple-component [1+2] and [1+3] condensation systems that enable the use of one knot and two or three linker units for the synthesis of hexagonal and tetragonal multiple-component covalent organic frameworks. Unlike two-component systems, multiple-component covalent organic frameworks feature asymmetric tiling of organic units into anisotropic skeletons and unusually shaped pores. This strategy not only expands the structural complexity of skeletons and pores but also greatly enhances their structural diversity. This synthetic platform is also widely applicable to multiple-component electron donor-acceptor systems, which lead to electronic properties that are not simply linear summations of those of the conventional [1+1] counterparts.
Stochastic Modeling of Airlines' Scheduled Services Revenue
NASA Technical Reports Server (NTRS)
Hamed, M. M.
1999-01-01
Airlines' revenue generated from scheduled services account for the major share in the total revenue. As such, predicting airlines' total scheduled services revenue is of great importance both to the governments (in case of national airlines) and private airlines. This importance stems from the need to formulate future airline strategic management policies, determine government subsidy levels, and formulate governmental air transportation policies. The prediction of the airlines' total scheduled services revenue is dealt with in this paper. Four key components of airline's scheduled services are considered. These include revenues generated from passenger, cargo, mail, and excess baggage. By addressing the revenue generated from each schedule service separately, air transportation planners and designers arc able to enhance their ability to formulate specific strategies for each component. Estimation results clearly indicate that the four stochastic processes (scheduled services components) are represented by different Box-Jenkins ARIMA models. The results demonstrate the appropriateness of the developed models and their ability to provide air transportation planners with future information vital to the planning and design processes.
Stochastic Modeling of Airlines' Scheduled Services Revenue
NASA Technical Reports Server (NTRS)
Hamed, M. M.
1999-01-01
Airlines' revenue generated from scheduled services account for the major share in the total revenue. As such, predicting airlines' total scheduled services revenue is of great importance both to the governments (in case of national airlines) and private airlines. This importance stems from the need to formulate future airline strategic management policies, determine government subsidy levels, and formulate governmental air transportation policies. The prediction of the airlines' total scheduled services revenue is dealt with in this paper. Four key components of airline's scheduled services are considered. These include revenues generated from passenger, cargo, mail, and excess baggage. By addressing the revenue generated from each schedule service separately, air transportation planners and designers are able to enhance their ability to formulate specific strategies for each component. Estimation results clearly indicate that the four stochastic processes (scheduled services components) are represented by different Box-Jenkins ARIMA models. The results demonstrate the appropriateness of the developed models and their ability to provide air transportation planners with future information vital to the planning and design processes.
Tolerance to Effects of Cocaine on Behavior under a Response-Initiated Fixed-Interval Schedule
ERIC Educational Resources Information Center
Weaver, Matthew T.; Branch, Marc N.
2008-01-01
Tolerance to effects of cocaine can be modulated by schedules of reinforcement. With multiple ratio schedules, research has shown an inverse relationship between ratio requirement and amount of tolerance that resulted from daily administration of the drug. In contrast, tolerance to the effects of cocaine on behavior under multiple interval…
Cheong, Jadeera Phaik Geok; Lay, Brendan; Grove, J. Robert; Medic, Nikola; Razman, Rizal
2012-01-01
To overcome the weakness of the contextual interference (CI) effect within applied settings, Brady, 2008 recommended that the amount of interference be manipulated. This study investigated the effect of five practice schedules on the learning of three field hockey skills. Fifty-five pre-university students performed a total of 90 trials for each skill under blocked, mixed or random practice orders. Results showed a significant time effect with all five practice conditions leading to improvements in acquisition and learning of the skills. No significant differences were found between the groups. The findings of the present study did not support the CI effect and suggest that either blocked, mixed, or random practice schedules can be used effectively when structuring practice for beginners. Key pointsThe contextual interference effect did not surface when using sport skills.There appears to be no difference between blocked and random practice schedules in the learning of field hockey skills.Low (blocked), moderate (mixed) or high (random) interference practice schedules can be used effectively when conducting a multiple skill practice session for beginners. PMID:24149204
Cheong, Jadeera Phaik Geok; Lay, Brendan; Grove, J Robert; Medic, Nikola; Razman, Rizal
2012-01-01
To overcome the weakness of the contextual interference (CI) effect within applied settings, Brady, 2008 recommended that the amount of interference be manipulated. This study investigated the effect of five practice schedules on the learning of three field hockey skills. Fifty-five pre-university students performed a total of 90 trials for each skill under blocked, mixed or random practice orders. Results showed a significant time effect with all five practice conditions leading to improvements in acquisition and learning of the skills. No significant differences were found between the groups. The findings of the present study did not support the CI effect and suggest that either blocked, mixed, or random practice schedules can be used effectively when structuring practice for beginners. Key pointsThe contextual interference effect did not surface when using sport skills.There appears to be no difference between blocked and random practice schedules in the learning of field hockey skills.Low (blocked), moderate (mixed) or high (random) interference practice schedules can be used effectively when conducting a multiple skill practice session for beginners.
Messer, Michael M; Haller, Irina V
2017-01-01
Objective: Depression is a common condition among patients with multiple sclerosis and often becomes resistant to oral antidepressants. We report a patient with multiple sclerosis who developed severe treatment-resistant depression and who was successfully treated with intravenous ketamine over the period of two years. Methods: Ketamine treatment protocol included an initial series of six treatments administered every other day, followed by a maintenance schedule. Ketamine was administered intravenously at 0.5mg/kg of ideal body weight over 40 minutes. Depression symptoms were measured using Beck Depression Index. Results: The patient's Beck Depression Index score prior to initiating ketamine treatment was 38, corresponding to severe depression. Response to treatment, defined as 50-percent reduction in Beck Depression Index score, was observed after five treatments. For this patient, the maintenance schedule ranged from a weekly treatment to one treatment every three weeks. During the two-year observation period, this patient was able to maintain a stable non-depressed mood and had no worsening of her MS symptoms. Conclusion: Ketamine may be an alternative treatment for resistant depression and may have a special use in patients with multiple sclerosis.
Further evaluation of methods to identify matched stimulation.
Rapp, John T
2007-01-01
The effects of preferred stimulation on the vocal stereotypy of 2 individuals were evaluated in two experiments. The results of Experiment 1 showed that (a) the vocal stereotypy of both participants persisted in the absence of social consequences, (b) 1 participant manipulated toys that did and did not produce auditory stimulation, but only sound-producing toys decreased his vocal stereotypy, and (c) only noncontingent music decreased vocal stereotypy for the other participant, but sterotypy paradoxically increased when toys were presented with music. Using a three-component multiple schedule, the results of Experiment 2 showed that the vocal stereotypy of both participants remained below preintervention levels following the removal of auditory stimulation and that 1 participant's vocal stereotypy increased following the removal of contingent reprimands. These patterns suggest that auditory stimulation functioned as an abolishing operation for vocal stereotypy and reprimands functioned as an establishing operation for vocal stereotypy. Together, the two experiments provide a method for identifying alternative stimulation that may substitute for automatically reinforced behavior.
Íbias, Javier; Pellón, Ricardo; Sanabria, Federico
2015-02-01
Recent research has suggested that frequent short bursts of activity characterize hyperactivity associated with attention deficit hyperactivity disorder (ADHD). This study determined whether such pattern is also visible in schedule-induced polydipsia (SIP) in the spontaneously hypertensive rat (SHR), an animal model of ADHD. Male SHR, Wistar Kyoto (WKY) and Wistar rats were exposed to 40 sessions of SIP using a multiple fixed-time (FT) schedule of food delivery with FT 30-s and FT 90-s components. Stable performance was analyzed to determine the extent to which SIP-associated drinking is organized in bouts. The Bi-Exponential Refractory Model (BERM) of free-operant performance was applied to schedule-induced licks. A model comparison analysis supported BERM as a description of SIP episodes: licks were not produced at a constant rate but organized into bouts within drinking episodes. FT 30-s induced similar overall licking rates, latencies to first licks and episode durations across strains; FT 90-s induced longer episode durations in SHRs and reduced licking rate in WKY and Wistar rats to nearly baseline levels. Across schedules, SHRs made more and shorter bouts when compared to the other strains. These results suggest an incentive-induced hyperactivity in SHR that has been observed in operant behaviour and in children with ADHD. Copyright © 2014 Elsevier B.V. All rights reserved.
ERIC Educational Resources Information Center
Pelios, Lillian V.; MacDuff, Gregory S.; Axelrod, Saul
2003-01-01
This study evaluated a treatment package to improve on-task academic skills by three children with autism. Program components included delayed reinforcement for on-task and on-schedule responding, fading of instructional prompts and instructor's presence, unpredictable supervision, and response cost for off-task responding. On-task and on-schedule…
Polarized BRDF for coatings based on three-component assumption
NASA Astrophysics Data System (ADS)
Liu, Hong; Zhu, Jingping; Wang, Kai; Xu, Rong
2017-02-01
A pBRDF(polarized bidirectional reflection distribution function) model for coatings is given based on three-component reflection assumption in order to improve the polarized scattering simulation capability for space objects. In this model, the specular reflection is given based on microfacet theory, the multiple reflection and volume scattering are given separately according to experimental results. The polarization of specular reflection is considered from Fresnel's law, and both multiple reflection and volume scattering are assumed depolarized. Simulation and measurement results of two satellite coating samples SR107 and S781 are given to validate that the pBRDF modeling accuracy can be significantly improved by the three-component model given in this paper.
NASA Technical Reports Server (NTRS)
Hall, Brendan (Inventor); Bonk, Ted (Inventor); Varadarajan, Srivatsan (Inventor); Smithgall, William Todd (Inventor); DeLay, Benjamin F. (Inventor)
2017-01-01
Systems and methods for systematic hybrid network scheduling for multiple traffic classes with host timing and phase constraints are provided. In certain embodiments, a method of scheduling communications in a network comprises scheduling transmission of virtual links pertaining to a first traffic class on a global schedule to coordinate transmission of the virtual links pertaining to the first traffic class across all transmitting end stations on the global schedule; and scheduling transmission of each virtual link pertaining to a second traffic class on a local schedule of the respective transmitting end station from which each respective virtual link pertaining to the second traffic class is transmitted such that transmission of each virtual link pertaining to the second traffic class is coordinated only at the respective end station from which each respective virtual link pertaining to the second traffic class is transmitted.
Do Conditional Reinforcers Count?
ERIC Educational Resources Information Center
Davison, Michael; Baum, William M.
2006-01-01
Six pigeons were trained on a procedure in which seven components arranged different food-delivery ratios on concurrent variable-interval schedules each session. The components were unsignaled, lasted for 10 food deliveries, and occurred in random order with a 60-s blackout between components. The schedules were arranged using a switching-key…
Abstract-Reasoning Software for Coordinating Multiple Agents
NASA Technical Reports Server (NTRS)
Clement, Bradley; Barrett, Anthony; Rabideau, Gregg; Knight, Russell
2003-01-01
A computer program for scheduling the activities of multiple agents that share limited resources has been incorporated into the Automated Scheduling and Planning Environment (ASPEN) software system, aspects of which have been reported in several previous NASA Tech Briefs articles. In the original intended application, the agents would be multiple spacecraft and/or robotic vehicles engaged in scientific exploration of distant planets. The program could also be used on Earth in such diverse settings as production lines and military maneuvers. This program includes a planning/scheduling subprogram of the iterative repair type that reasons about the activities of multiple agents at abstract levels in order to greatly improve the scheduling of their use of shared resources. The program summarizes the information about the constraints on, and resource requirements of, abstract activities on the basis of the constraints and requirements that pertain to their potential refinements (decomposition into less-abstract and ultimately to primitive activities). The advantage of reasoning about summary information is that time needed to find consistent schedules is exponentially smaller than the time that would be needed for reasoning about the same tasks at the primitive level.
Xiang, Wei; Yin, Jiao; Lim, Gino
2015-02-01
Operating room (OR) surgery scheduling determines the individual surgery's operation start time and assigns the required resources to each surgery over a schedule period, considering several constraints related to a complete surgery flow and the multiple resources involved. This task plays a decisive role in providing timely treatments for the patients while balancing hospital resource utilization. The originality of the present study is to integrate the surgery scheduling problem with real-life nurse roster constraints such as their role, specialty, qualification and availability. This article proposes a mathematical model and an ant colony optimization (ACO) approach to efficiently solve such surgery scheduling problems. A modified ACO algorithm with a two-level ant graph model is developed to solve such combinatorial optimization problems because of its computational complexity. The outer ant graph represents surgeries, while the inner graph is a dynamic resource graph. Three types of pheromones, i.e. sequence-related, surgery-related, and resource-related pheromone, fitting for a two-level model are defined. The iteration-best and feasible update strategy and local pheromone update rules are adopted to emphasize the information related to the good solution in makespan, and the balanced utilization of resources as well. The performance of the proposed ACO algorithm is then evaluated using the test cases from (1) the published literature data with complete nurse roster constraints, and 2) the real data collected from a hospital in China. The scheduling results using the proposed ACO approach are compared with the test case from both the literature and the real life hospital scheduling. Comparison results with the literature shows that the proposed ACO approach has (1) an 1.5-h reduction in end time; (2) a reduction in variation of resources' working time, i.e. 25% for ORs, 50% for nurses in shift 1 and 86% for nurses in shift 2; (3) an 0.25h reduction in individual maximum overtime (OT); and (4) an 42% reduction in the total OT of nurses. Comparison results with the real 10-workday hospital scheduling further show the advantage of the ACO in several measurements. Instead of assigning all surgeries by a surgeon to only one OR and the same nurses by traditional manual approach in hospital, ACO realizes a more balanced surgery arrangement by assigning the surgeries to different ORs and nurses. It eventually leads to shortening the end time within the confidential interval of [7.4%, 24.6%] with 95% confidence level. The ACO approach proposed in this paper efficiently solves the surgery scheduling problem with daily nurse roster while providing a shortened end time and relatively balanced resource allocations. It also supports the advantage of integrating the surgery scheduling with the nurse scheduling and the efficiency of systematic optimization considering a complete three-stage surgery flow and resources involved. Copyright © 2014 Elsevier B.V. All rights reserved.
Astronaut Office Scheduling System Software
NASA Technical Reports Server (NTRS)
Brown, Estevancio
2010-01-01
AOSS is a highly efficient scheduling application that uses various tools to schedule astronauts weekly appointment information. This program represents an integration of many technologies into a single application to facilitate schedule sharing and management. It is a Windows-based application developed in Visual Basic. Because the NASA standard office automation load environment is Microsoft-based, Visual Basic provides AO SS developers with the ability to interact with Windows collaboration components by accessing objects models from applications like Outlook and Excel. This also gives developers the ability to create newly customizable components that perform specialized tasks pertaining to scheduling reporting inside the application. With this capability, AOSS can perform various asynchronous tasks, such as gathering/ sending/ managing astronauts schedule information directly to their Outlook calendars at any time.
ERIC Educational Resources Information Center
Bejarano, Rafael; Hackenberg, Timothy D.
2007-01-01
Two experiments with pigeons investigated the effects of contingencies between interresponse times (IRTs) and the transitions between the components of 2- and 4-component chained schedules (Experiments 1 and 2, respectively). The probability of component transitions varied directly with the most recent (Lag 0) IRT in some experimental conditions…
Morphine tolerance as a function of ratio schedule: response requirement or unit price?
Hughes, Christine E; Sigmon, Stacey C; Pitts, Raymond C; Dykstra, Linda A
2005-05-01
Key pecking by 3 pigeons was maintained by a multiple fixed-ratio 10, fixed-ratio 30, fixed-ratio 90 schedule of food presentation. Components differed with respect to amount of reinforcement, such that the unit price was 10 responses per 1-s access to food. Acute administration of morphine, l-methadone, and cocaine dose-dependently decreased overall response rates in each of the components. When a rate decreasing dose of morphine was administered daily, tolerance, as measured by an increase in the dose that reduced response rates to 50% of control (i.e., the ED50 value), developed in each of the components; however, the degree of tolerance was smallest in the fixed-ratio 90 component (i.e., the ED50 value increased the least). When the l-methadone dose-effect curve was redetermined during the chronic morphine phase, the degree of cross-tolerance conferred to l-methadone was similar across components, suggesting that behavioral variables may not influence the degree of cross-tolerance between opioids. During the chronic phase, the cocaine dose-effect curve shifted to the right for 2 pigeons and to the left for 1 pigeon, which is consistent with predictions based on the lack of pharmacological similarity between morphine and cocaine. When the morphine, l-methadone, and cocaine dose-effect curves were redetermined after chronic morphine administration ended, the morphine and l-methadone ED50s replicated those obtained prior to chronic morphine administration. The morphine data suggest that the fixed-ratio value (i.e., the absolute output) determines the degree of tolerance and not the unit price.
An Efficient Downlink Scheduling Strategy Using Normal Graphs for Multiuser MIMO Wireless Systems
NASA Astrophysics Data System (ADS)
Chen, Jung-Chieh; Wu, Cheng-Hsuan; Lee, Yao-Nan; Wen, Chao-Kai
Inspired by the success of the low-density parity-check (LDPC) codes in the field of error-control coding, in this paper we propose transforming the downlink multiuser multiple-input multiple-output scheduling problem into an LDPC-like problem using the normal graph. Based on the normal graph framework, soft information, which indicates the probability that each user will be scheduled to transmit packets at the access point through a specified angle-frequency sub-channel, is exchanged among the local processors to iteratively optimize the multiuser transmission schedule. Computer simulations show that the proposed algorithm can efficiently schedule simultaneous multiuser transmission which then increases the overall channel utilization and reduces the average packet delay.
Boyer, S A
1999-01-01
There is an alternative to classroom lecture that provides faster, more complete instruction and introduces the learner to clinical application of skills in a safe environment. This teaching style uses multiple media to present professional, published resources that provide excellent quality, topic-specific information. The benefits of this type of teaching/learning module include improved use of student and instructor time, scheduling advantages, increased learning, revenue generation potential, and student empowerment. With this approach, a strong, sound educational base is built, and each course includes some degree or form of clinical application as a key component.
An Example of Discovery Research Involving the Transfer of Stimulus Control
2005-01-01
The initial purpose of the present study was to replicate procedures for teaching preschool children to recruit attention at appropriate times by having an experimenter signal the availability and unavailability of attention (i.e., arrange a multiple schedule involving reinforcement and extinction; Tiger & Hanley, 2004). Following the development of discriminated social responding, the schedule-correlated stimuli were removed (i.e., a mixed schedule of reinforcement was arranged). However, discriminated responding continued during these conditions. Further evaluation suggested that stimulus control over children's social responding had transferred from the schedule-correlated stimuli to the delivery of reinforcement. The effect of a history of reinforcement under multiple-schedule conditions on performance under mixed schedules was then replicated with 2 participants in a reversal design. These findings suggest that following experience with schedule-correlated stimuli, these stimuli may be removed with only modest disruption to discriminated responding. PMID:16463530
Ginsburg, B C; Lamb, R J
2014-01-01
BACKGROUND AND PURPOSE Drugs that more potently or effectively reduce ethanol-maintained behaviour versus an alternative are considered selective and are considered promising pharmacotherapies for alcoholism. Such results are often obtained using separate groups or multiple schedules where ethanol and the alternative are available alone or sequentially. Recently, we observed that when ethanol and food were available sequentially under a multiple schedule, fluvoxamine and varenicline were selective; yet this selectivity disappeared when ethanol and food were concurrently available. EXPERIMENTAL APPROACH We examined the generality of these findings by comparing doses of several drugs required to decrease ethanol- and food-maintained responding under a multiple schedule and under a concurrent schedule. Effects were determined for chlordiazepoxide, 2,5-dimethoxy-4-iodoamphetamine (DOI), meta-chlorophenylpiperazine (mCPP), morphine, naltrexone and d-amphetamine. KEY RESULTS Under the multiple schedule, ED50 values for decreases in ethanol-maintained responding were significantly different and lower than ED50s for decreases in food-maintained responding (demonstrating selectivity) for each drug except for chlordiazepoxide (which was equipotent) and naltrexone (which did not affect responding). However, this selectivity vanished or even inverted under the concurrent schedule, such that ED50 values for decreasing ethanol- and food-maintained responding were not different (or, following DOI, the ED50 for food-maintained responding was lower than for ethanol-maintained responding). CONCLUSIONS AND IMPLICATIONS Results are consistent with those seen following fluvoxamine and varenicline administration, and suggest that selectivity is assay-dependent. These results indicate the need for careful interpretation of selective drug effects, especially when obtained in situations where ethanol or the alternative is the only programmed reinforcement available. PMID:24697498
Ginsburg, B C; Lamb, R J
2014-07-01
Drugs that more potently or effectively reduce ethanol-maintained behaviour versus an alternative are considered selective and are considered promising pharmacotherapies for alcoholism. Such results are often obtained using separate groups or multiple schedules where ethanol and the alternative are available alone or sequentially. Recently, we observed that when ethanol and food were available sequentially under a multiple schedule, fluvoxamine and varenicline were selective; yet this selectivity disappeared when ethanol and food were concurrently available. We examined the generality of these findings by comparing doses of several drugs required to decrease ethanol- and food-maintained responding under a multiple schedule and under a concurrent schedule. Effects were determined for chlordiazepoxide, 2,5-dimethoxy-4-iodoamphetamine (DOI), meta-chlorophenylpiperazine (mCPP), morphine, naltrexone and d-amphetamine. Under the multiple schedule, ED50 values for decreases in ethanol-maintained responding were significantly different and lower than ED50 s for decreases in food-maintained responding (demonstrating selectivity) for each drug except for chlordiazepoxide (which was equipotent) and naltrexone (which did not affect responding). However, this selectivity vanished or even inverted under the concurrent schedule, such that ED50 values for decreasing ethanol- and food-maintained responding were not different (or, following DOI, the ED50 for food-maintained responding was lower than for ethanol-maintained responding). Results are consistent with those seen following fluvoxamine and varenicline administration, and suggest that selectivity is assay-dependent. These results indicate the need for careful interpretation of selective drug effects, especially when obtained in situations where ethanol or the alternative is the only programmed reinforcement available. © 2014 The British Pharmacological Society.
Integration of domain and resource-based reasoning for real-time control in dynamic environments
NASA Technical Reports Server (NTRS)
Morgan, Keith; Whitebread, Kenneth R.; Kendus, Michael; Cromarty, Andrew S.
1993-01-01
A real-time software controller that successfully integrates domain-based and resource-based control reasoning to perform task execution in a dynamically changing environment is described. The design of the controller is based on the concept of partitioning the process to be controlled into a set of tasks, each of which achieves some process goal. It is assumed that, in general, there are multiple ways (tasks) to achieve a goal. The controller dynamically determines current goals and their current criticality, choosing and scheduling tasks to achieve those goals in the time available. It incorporates rule-based goal reasoning, a TMS-based criticality propagation mechanism, and a real-time scheduler. The controller has been used to build a knowledge-based situation assessment system that formed a major component of a real-time, distributed, cooperative problem solving system built under DARPA contract. It is also being employed in other applications now in progress.
Wearden, J H; Lejeune, Helga
2006-02-28
The article deals with response rates (mainly running and peak or terminal rates) on simple and on some mixed-FI schedules and explores the idea that these rates are determined by the average delay of reinforcement for responses occurring during the response periods that the schedules generate. The effects of reinforcement delay are assumed to be mediated by a hyperbolic delay of reinforcement gradient. The account predicts that (a) running rates on simple FI schedules should increase with increasing rate of reinforcement, in a manner close to that required by Herrnstein's equation, (b) improving temporal control during acquisition should be associated with increasing running rates, (c) two-valued mixed-FI schedules with equiprobable components should produce complex results, with peak rates sometimes being higher on the longer component schedule, and (d) that effects of reinforcement probability on mixed-FI should affect the response rate at the time of the shorter component only. All these predictions were confirmed by data, although effects in some experiments remain outside the scope of the model. In general, delay of reinforcement as a determinant of response rate on FI and related schedules (rather than temporal control on such schedules) seems a useful starting point for a more thorough analysis of some neglected questions about performance on FI and related schedules.
Morita, Yuko; Sasai-Sakuma, Taeko; Asaoka, Shoichi; Inoue, Yuichi
2015-10-15
This study investigated the prevalence and risk factors of insufficient sleep syndrome (ISS), and factors associated with daytime dysfunction in the disorder in Japanese young adults. In this cross-sectional study, a web-based questionnaire survey was used to assess demographic variables, sleep habits and quality, depressive symptoms, and health-related quality of life (HRQOL) in 2,276 participants aged 20-25. Eleven percent of participants were classified as having ISS. Multiple logistic regression analysis revealed that the presence of ISS was significantly associated with social status (student or full-time employee). The participants with ISS had significantly higher depression scores and lower mental component summary scores than healthy sleepers. In the participants with ISS, a delayed sleep-wake schedule was extracted as a factor associated with worse mental component summary. Results indicate a relatively high proportion of Japanese young adults suffer from ISS, and that the condition is associated with a social status of student or full-time employee. Moreover, a delayed sleep-wake schedule may lead to further deterioration of mental HRQOL in ISS-affected persons. © 2015 American Academy of Sleep Medicine.
2011-09-01
No. BAA09-69 ABSTRACT Using multiple deployments of an 80-element, three-component borehole seismic array stretching from the surface to 2.3 km...NNSA). 14. ABSTRACT Using multiple deployments of an 80-element, three-component borehole seismic array stretching from the surface to 2.3 km depth...generated using the direct Green’s function (DGF) method of Friederich and Dalkolmo (1995). This method synthesizes the seismic wavefield for a spherically
NASA Astrophysics Data System (ADS)
Seo, Junyeong; Sung, Youngchul
2018-06-01
In this paper, an efficient transmit beam design and user scheduling method is proposed for multi-user (MU) multiple-input single-output (MISO) non-orthogonal multiple access (NOMA) downlink, based on Pareto-optimality. The proposed beam design and user scheduling method groups simultaneously-served users into multiple clusters with practical two users in each cluster, and then applies spatical zeroforcing (ZF) across clusters to control inter-cluster interference (ICI) and Pareto-optimal beam design with successive interference cancellation (SIC) to two users in each cluster to remove interference to strong users and leverage signal-to-interference-plus-noise ratios (SINRs) of interference-experiencing weak users. The proposed method has flexibility to control the rates of strong and weak users and numerical results show that the proposed method yields good performance.
Optimization of Airport Surface Traffic: A Case-Study of Incheon International Airport
NASA Technical Reports Server (NTRS)
Eun, Yeonju; Jeon, Daekeun; Lee, Hanbong; Jung, Yoon C.; Zhu, Zhifan; Jeong, Myeongsook; Kim, Hyounkong; Oh, Eunmi; Hong, Sungkwon
2017-01-01
This study aims to develop a controllers decision support tool for departure and surface management of ICN. Airport surface traffic optimization for Incheon International Airport (ICN) in South Korea was studied based on the operational characteristics of ICN and airspace of Korea. For surface traffic optimization, a multiple runway scheduling problem and a taxi scheduling problem were formulated into two Mixed Integer Linear Programming (MILP) optimization models. The Miles-In-Trail (MIT) separation constraint at the departure fix shared by the departure flights from multiple runways and the runway crossing constraints due to the taxi route configuration specific to ICN were incorporated into the runway scheduling and taxiway scheduling problems, respectively. Since the MILP-based optimization model for the multiple runway scheduling problem may be computationally intensive, computation times and delay costs of different solving methods were compared for a practical implementation. This research was a collaboration between Korea Aerospace Research Institute (KARI) and National Aeronautics and Space Administration (NASA).
Optimization of Airport Surface Traffic: A Case-Study of Incheon International Airport
NASA Technical Reports Server (NTRS)
Eun, Yeonju; Jeon, Daekeun; Lee, Hanbong; Jung, Yoon Chul; Zhu, Zhifan; Jeong, Myeong-Sook; Kim, Hyoun Kyoung; Oh, Eunmi; Hong, Sungkwon
2017-01-01
This study aims to develop a controllers' decision support tool for departure and surface management of ICN. Airport surface traffic optimization for Incheon International Airport (ICN) in South Korea was studied based on the operational characteristics of ICN and airspace of Korea. For surface traffic optimization, a multiple runway scheduling problem and a taxi scheduling problem were formulated into two Mixed Integer Linear Programming (MILP) optimization models. The Miles-In-Trail (MIT) separation constraint at the departure fix shared by the departure flights from multiple runways and the runway crossing constraints due to the taxi route configuration specific to ICN were incorporated into the runway scheduling and taxiway scheduling problems, respectively. Since the MILP-based optimization model for the multiple runway scheduling problem may be computationally intensive, computation times and delay costs of different solving methods were compared for a practical implementation. This research was a collaboration between Korea Aerospace Research Institute (KARI) and National Aeronautics and Space Administration (NASA).
Efficient multitasking: parallel versus serial processing of multiple tasks
Fischer, Rico; Plessow, Franziska
2015-01-01
In the context of performance optimizations in multitasking, a central debate has unfolded in multitasking research around whether cognitive processes related to different tasks proceed only sequentially (one at a time), or can operate in parallel (simultaneously). This review features a discussion of theoretical considerations and empirical evidence regarding parallel versus serial task processing in multitasking. In addition, we highlight how methodological differences and theoretical conceptions determine the extent to which parallel processing in multitasking can be detected, to guide their employment in future research. Parallel and serial processing of multiple tasks are not mutually exclusive. Therefore, questions focusing exclusively on either task-processing mode are too simplified. We review empirical evidence and demonstrate that shifting between more parallel and more serial task processing critically depends on the conditions under which multiple tasks are performed. We conclude that efficient multitasking is reflected by the ability of individuals to adjust multitasking performance to environmental demands by flexibly shifting between different processing strategies of multiple task-component scheduling. PMID:26441742
Efficient multitasking: parallel versus serial processing of multiple tasks.
Fischer, Rico; Plessow, Franziska
2015-01-01
In the context of performance optimizations in multitasking, a central debate has unfolded in multitasking research around whether cognitive processes related to different tasks proceed only sequentially (one at a time), or can operate in parallel (simultaneously). This review features a discussion of theoretical considerations and empirical evidence regarding parallel versus serial task processing in multitasking. In addition, we highlight how methodological differences and theoretical conceptions determine the extent to which parallel processing in multitasking can be detected, to guide their employment in future research. Parallel and serial processing of multiple tasks are not mutually exclusive. Therefore, questions focusing exclusively on either task-processing mode are too simplified. We review empirical evidence and demonstrate that shifting between more parallel and more serial task processing critically depends on the conditions under which multiple tasks are performed. We conclude that efficient multitasking is reflected by the ability of individuals to adjust multitasking performance to environmental demands by flexibly shifting between different processing strategies of multiple task-component scheduling.
NASA Astrophysics Data System (ADS)
Pulusani, Praneeth R.
As the number of electric vehicles on the road increases, current power grid infrastructure will not be able to handle the additional load. Some approaches in the area of Smart Grid research attempt to mitigate this, but those approaches alone will not be sufficient. Those approaches and traditional solution of increased power production can result in an insufficient and imbalanced power grid. It can lead to transformer blowouts, blackouts and blown fuses, etc. The proposed solution will supplement the ``Smart Grid'' to create a more sustainable power grid. To solve or mitigate the magnitude of the problem, measures can be taken that depend on weather forecast models. For instance, wind and solar forecasts can be used to create first order Markov chain models that will help predict the availability of additional power at certain times. These models will be used in conjunction with the information processing layer and bidirectional signal processing components of electric vehicle charging systems, to schedule the amount of energy transferred per time interval at various times. The research was divided into three distinct components: (1) Renewable Energy Supply Forecast Model, (2) Energy Demand Forecast from PEVs, and (3) Renewable Energy Resource Estimation. For the first component, power data from a local wind turbine, and weather forecast data from NOAA were used to develop a wind energy forecast model, using a first order Markov chain model as the foundation. In the second component, additional macro energy demand from PEVs in the Greater Rochester Area was forecasted by simulating concurrent driving routes. In the third component, historical data from renewable energy sources was analyzed to estimate the renewable resources needed to offset the energy demand from PEVs. The results from these models and components can be used in the smart grid applications for scheduling and delivering energy. Several solutions are discussed to mitigate the problem of overloading transformers, lack of energy supply, and higher utility costs.
Student Scheduling Choices and Time to Completion of a Two-Year Credential
ERIC Educational Resources Information Center
Rzeznik, Mark A.
2017-01-01
All students need to decide how to schedule their classes to complete their credential. This study examined three types of student scheduling choices: full-block scheduling, partial-block scheduling, and traditional scheduling to address two research questions: How do the choices students make in scheduling classes-using three scheduling…
NASA Technical Reports Server (NTRS)
Robinson, John E.
2014-01-01
The Federal Aviation Administration's Next Generation Air Transportation System will combine advanced air traffic management technologies, performance-based procedures, and state-of-the-art avionics to maintain efficient operations throughout the entire arrival phase of flight. Flight deck Interval Management (FIM) operations are expected to use sophisticated airborne spacing capabilities to meet precise in-trail spacing from top-of-descent to touchdown. Recent human-in-the-loop simulations by the National Aeronautics and Space Administration have found that selection of the assigned spacing goal using the runway schedule can lead to premature interruptions of the FIM operation during periods of high traffic demand. This study compares three methods for calculating the assigned spacing goal for a FIM operation that is also subject to time-based metering constraints. The particular paradigms investigated include: one based upon the desired runway spacing interval, one based upon the desired meter fix spacing interval, and a composite method that combines both intervals. These three paradigms are evaluated for the primary arrival procedures to Phoenix Sky Harbor International Airport using the entire set of Rapid Update Cycle wind forecasts from 2011. For typical meter fix and runway spacing intervals, the runway- and meter fix-based paradigms exhibit moderate FIM interruption rates due to their inability to consider multiple metering constraints. The addition of larger separation buffers decreases the FIM interruption rate but also significantly reduces the achievable runway throughput. The composite paradigm causes no FIM interruptions, and maintains higher runway throughput more often than the other paradigms. A key implication of the results with respect to time-based metering is that FIM operations using a single assigned spacing goal will not allow reduction of the arrival schedule's excess spacing buffer. Alternative solutions for conducting the FIM operation in a manner more compatible with the arrival schedule are discussed in detail.
Compound-Schedules Approaches to Noncompliance: Teaching Children When to Ask and When to Work
ERIC Educational Resources Information Center
Lambert, Joseph M.; Clohisy, Anne M.; Blair Barrows, S.; Houchins-Juarez, Nealetta J.
2017-01-01
Researchers have demonstrated for practitioners how to use multiple-schedules preparations to thin initially dense schedules of reinforcement during functional communication training, without sacrificing benefits associated with dense schedules of reinforcement for manding. However, special considerations may be required for practitioners to…
Zhang, Xiaona; Chen, Gang; Xu, Feng; Zhou, Kaina; Zhuang, Guihua
2016-01-01
After validation of the widely used health-related quality of life (HRQOL) generic measure, the Short Form 36 version 2 (SF-36v2), we investigated the HRQOL and associated factors of frontline railway workers in China. Ground workers, conductors, and train drivers were selected from Ankang Precinct by using a stratified cluster sampling technique. A total of 784 frontline railway workers participated in the survey. The reliability and validity of SF-36v2 was satisfactory. The physical component summary (PCS) scores of three subgroups attained the average range for the USA general population, whereas the mental component summary (MCS) scores were well below the range. Most domains scored below the norm, except for the physical functioning (PF) domain. Among three subgroups, train drivers reported significantly lower scores on MCS and six health domains (excluding PF and bodily pain (BP)). After controlled confounders, conductors had significantly higher PCS and MCS scores than ground workers. There is heterogeneity on risk factors among three subgroups, but having long or irregular working schedules was negatively associated with HRQOL in all subgroups. SF-36v2 is a reliable and valid HRQOL measurement in railway workers in China. The frontline railway workers’ physical health was comparative to American norms, whilst mental health was relatively worse. Long or irregular working schedules were the most important factors. PMID:27916919
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-26
...; Modifications 552.243-72 (Multiple Award Schedules) AGENCY: Office of Acquisition Policy, General Services... information collection requirement regarding the Modifications (Multiple Award Schedule) clause. DATES: Submit comments on or before: April 25, 2013. FOR FURTHER INFORMATION CONTACT: Ms. Dana Munson, General Services...
NASA Astrophysics Data System (ADS)
Koch, Julian; Cüneyd Demirel, Mehmet; Stisen, Simon
2018-05-01
The process of model evaluation is not only an integral part of model development and calibration but also of paramount importance when communicating modelling results to the scientific community and stakeholders. The modelling community has a large and well-tested toolbox of metrics to evaluate temporal model performance. In contrast, spatial performance evaluation does not correspond to the grand availability of spatial observations readily available and to the sophisticate model codes simulating the spatial variability of complex hydrological processes. This study makes a contribution towards advancing spatial-pattern-oriented model calibration by rigorously testing a multiple-component performance metric. The promoted SPAtial EFficiency (SPAEF) metric reflects three equally weighted components: correlation, coefficient of variation and histogram overlap. This multiple-component approach is found to be advantageous in order to achieve the complex task of comparing spatial patterns. SPAEF, its three components individually and two alternative spatial performance metrics, i.e. connectivity analysis and fractions skill score, are applied in a spatial-pattern-oriented model calibration of a catchment model in Denmark. Results suggest the importance of multiple-component metrics because stand-alone metrics tend to fail to provide holistic pattern information. The three SPAEF components are found to be independent, which allows them to complement each other in a meaningful way. In order to optimally exploit spatial observations made available by remote sensing platforms, this study suggests applying bias insensitive metrics which further allow for a comparison of variables which are related but may differ in unit. This study applies SPAEF in the hydrological context using the mesoscale Hydrologic Model (mHM; version 5.8), but we see great potential across disciplines related to spatially distributed earth system modelling.
The effects of differing response-force requirements on fixed-ratio responding of rats.
Alling, K; Poling, A
1995-01-01
Rats were exposed to two-component multiple schedules of food delivery. In the first experiment, 15 responses were required to produce food in both components. A downward force of 0.25 N (25 g) was always required to operate the response lever in one component. In the other, the required force was 0.25, 0.50, 1.00, or 2.00 N (25, 50, 100, or 200 g). In the second experiment, 0.25 N of force operated the lever in one component, but in the other, the force requirement for five consecutive responses at the beginning, middle, or end of each ratio was increased from 0.25 to 2.00 N. In the third experiment, the number of responses required to produce food was reduced from 15 to 5, and then to 1. Again, the effects of altering response force from 0.25 to 2.00 N were examined. In general, as response force increased in all experiments, mean response rates decreased and mean interresponse times increased. PMID:7751836
Loehle, C.; Van Deusen, P.; Wigley, T.B.; Mitchell, M.S.; Rutzmoser, S.H.; Aggett, J.; Beebe, J.A.; Smith, M.L.
2006-01-01
Wildlife-habitat relationship models have sometimes been linked with forest simulators to aid in evaluating outcomes of forest management alternatives. However, linking wildlife-habitat models with harvest scheduling software would provide a more direct method for assessing economic and ecological implications of alternative harvest schedules in commercial forest operations. We demonstrate an approach for frontier analyses of wildlife benefits using the Habplan harvest scheduler and spatially explicit wildlife response models in the context of operational forest planning. We used the Habplan harvest scheduler to plan commercial forest management over a 40-year horizon at a landscape scale under five scenarios: unmanaged, an unlimited block-size option both with and without riparian buffers, three cases with different block-size restrictions, and a set-asides scenario in which older stands were withheld from cutting. The potential benefit to wildlife was projected based on spatial models of bird guild richness and species probability of detection. Harvested wood volume provided a measure of scenario costs, which provides an indication of management feasibility. Of nine species and guilds, none appeared to benefit from 50 m riparian buffers, response to an unmanaged scenario was mixed and expensive, and block-size restrictions (maximum harvest unit size) provided no apparent benefit and in some cases were possibly detrimental to bird richness. A set-aside regime, however, appeared to provide significant benefits to all species and groups, probably through increased landscape heterogeneity and increased availability of older forest. Our approach shows promise for evaluating costs and benefits of forest management guidelines in commercial forest enterprises and improves upon the state of the art by utilizing an optimizing harvest scheduler as in commercial forest management, multiple measures of biodiversity (models for multiple species and guilds), and spatially explicit wildlife response models. ?? 2006 Elsevier B.V. All rights reserved.
NASA Astrophysics Data System (ADS)
Beiden, Sergey V.; Wagner, Robert F.; Campbell, Gregory; Metz, Charles E.; Chan, Heang-Ping; Nishikawa, Robert M.; Schnall, Mitchell D.; Jiang, Yulei
2001-06-01
In recent years, the multiple-reader, multiple-case (MRMC) study paradigm has become widespread for receiver operating characteristic (ROC) assessment of systems for diagnostic imaging and computer-aided diagnosis. We review how MRMC data can be analyzed in terms of the multiple components of the variance (case, reader, interactions) observed in those studies. Such information is useful for the design of pivotal studies from results of a pilot study and also for studying the effects of reader training. Recently, several of the present authors have demonstrated methods to generalize the analysis of multiple variance components to the case where unaided readers of diagnostic images are compared with readers who receive the benefit of a computer assist (CAD). For this case it is necessary to model the possibility that several of the components of variance might be reduced when readers incorporate the computer assist, compared to the unaided reading condition. We review results of this kind of analysis on three previously published MRMC studies, two of which were applications of CAD to diagnostic mammography and one was an application of CAD to screening mammography. The results for the three cases are seen to differ, depending on the reader population sampled and the task of interest. Thus, it is not possible to generalize a particular analysis of variance components beyond the tasks and populations actually investigated.
Wirtz, Anna; Giebel, Ole; Schomann, Carsten; Nachreiner, Friedhelm
2008-04-01
Periodic components inherent in actual schedules of flexible working hours and their interference with social rhythms were measured using spectrum analysis. The resulting indicators of periodicity and interference were then related to the reported social impairments of workers. The results show that a suppression of the 24 and the 168 h (seven-day) components (absence of periodicity) in the work schedules predicts reported social impairment. However, even if there are relatively strong 24 and 168 h components left in the work schedules, their interference with the social rhythm (using the phase difference between working hours and the utility of time) further predicts impairment. The results thus indicate that the periodicity of working hours and the amount of (social) desynchronization induced by flexible work schedules can be used both for predicting the impairing effects of the specific work schedules on social well-being as well as for the design of socially acceptable flexible work hours.
Interleaved Practice with Multiple Representations: Analyses with Knowledge Tracing Based Techniques
ERIC Educational Resources Information Center
Rau, Martina A.; Pardos, Zachary A.
2012-01-01
The goal of this paper is to use Knowledge Tracing to augment the results obtained from an experiment that investigated the effects of practice schedules using an intelligent tutoring system for fractions. Specifically, this experiment compared different practice schedules of multiple representations of fractions: representations were presented to…
Chen, Juan; Yu, Qing; Zhu, Ziyun; Peng, Yujia; Fang, Fang
2016-01-01
In natural scenes, multiple objects are usually presented simultaneously. How do specific areas of the brain respond to multiple objects based on their responses to each individual object? Previous functional magnetic resonance imaging (fMRI) studies have shown that the activity induced by a multiobject stimulus in the primary visual cortex (V1) can be predicted by the linear or nonlinear sum of the activities induced by its component objects. However, there has been little evidence from electroencephelogram (EEG) studies so far. Here we explored how V1 responded to multiple objects by comparing the EEG signals evoked by a three-grating stimulus with those evoked by its two components (the central grating and 2 flanking gratings). We focused on the earliest visual component C1 (onset latency of ∼50 ms) because it has been shown to reflect the feedforward responses of neurons in V1. We found that when the stimulus was unattended, the amplitude of the C1 evoked by the three-grating stimulus roughly equaled the sum of the amplitudes of the C1s evoked by its two components, regardless of the distances between these gratings. When the stimulus was attended, this linear spatial summation existed only when the three gratings were far apart from each other. When the three gratings were close to each other, the spatial summation became compressed. These results suggest that the earliest visual responses in V1 follow a linear summation rule when attention is not involved and that attention can affect the earliest interactions between multiple objects. Copyright © 2016 the American Physiological Society.
Xiang, Wei; Li, Chong
2015-01-01
Operating Room (OR) is the core sector in hospital expenditure, the operation management of which involves a complete three-stage surgery flow, multiple resources, prioritization of the various surgeries, and several real-life OR constraints. As such reasonable surgery scheduling is crucial to OR management. To optimize OR management and reduce operation cost, a short-term surgery scheduling problem is proposed and defined based on the survey of the OR operation in a typical hospital in China. The comprehensive operation cost is clearly defined considering both under-utilization and overutilization. A nested Ant Colony Optimization (nested-ACO) incorporated with several real-life OR constraints is proposed to solve such a combinatorial optimization problem. The 10-day manual surgery schedules from a hospital in China are compared with the optimized schedules solved by the nested-ACO. Comparison results show the advantage using the nested-ACO in several measurements: OR-related time, nurse-related time, variation in resources' working time, and the end time. The nested-ACO considering real-life operation constraints such as the difference between first and following case, surgeries priority, and fixed nurses in pre/post-operative stage is proposed to solve the surgery scheduling optimization problem. The results clearly show the benefit of using the nested-ACO in enhancing the OR management efficiency and minimizing the comprehensive overall operation cost.
Scheduling optimization of design stream line for production research and development projects
NASA Astrophysics Data System (ADS)
Liu, Qinming; Geng, Xiuli; Dong, Ming; Lv, Wenyuan; Ye, Chunming
2017-05-01
In a development project, efficient design stream line scheduling is difficult and important owing to large design imprecision and the differences in the skills and skill levels of employees. The relative skill levels of employees are denoted as fuzzy numbers. Multiple execution modes are generated by scheduling different employees for design tasks. An optimization model of a design stream line scheduling problem is proposed with the constraints of multiple executive modes, multi-skilled employees and precedence. The model considers the parallel design of multiple projects, different skills of employees, flexible multi-skilled employees and resource constraints. The objective function is to minimize the duration and tardiness of the project. Moreover, a two-dimensional particle swarm algorithm is used to find the optimal solution. To illustrate the validity of the proposed method, a case is examined in this article, and the results support the feasibility and effectiveness of the proposed model and algorithm.
Air Traffic Management Technology Demonstration-1 Concept of Operations (ATD-1 ConOps), Version 2.0
NASA Technical Reports Server (NTRS)
Baxley, Brian T.; Johnson, William C.; Swenson, Harry N.; Robinson, John E.; Prevot, Tom; Callantine, Todd J.; Scardina, John; Greene, Michael
2013-01-01
This document is an update to the operations and procedures envisioned for NASA s Air Traffic Management (ATM) Technology Demonstration #1 (ATD-1). The ATD-1 Concept of Operations (ConOps) integrates three NASA technologies to achieve high throughput, fuel-efficient arrival operations into busy terminal airspace. They are Traffic Management Advisor with Terminal Metering (TMA-TM) for precise time-based schedules to the runway and points within the terminal area, Controller-Managed Spacing (CMS) decision support tools for terminal controllers to better manage aircraft delay using speed control, and Flight deck Interval Management (FIM) avionics and flight crew procedures to conduct airborne spacing operations. The ATD-1 concept provides de-conflicted and efficient operations of multiple arrival streams of aircraft, passing through multiple merge points, from top-of-descent (TOD) to the Final Approach Fix. These arrival streams are Optimized Profile Descents (OPDs) from en route altitude to the runway, using primarily speed control to maintain separation and schedule. The ATD-1 project is currently addressing the challenges of integrating the three technologies, and their implantation into an operational environment. The ATD-1 goals include increasing the throughput of high-density airports, reducing controller workload, increasing efficiency of arrival operations and the frequency of trajectory-based operations, and promoting aircraft ADS-B equipage.
NASA's ATM Technology Demonstration-1: Integrated Concept of Arrival Operations
NASA Technical Reports Server (NTRS)
Baxley, Brian T.; Swenson, Harry N.; Prevot, Thomas; Callantine, Todd J.
2012-01-01
This paper describes operations and procedures envisioned for NASA s Air Traffic Management (ATM) Technology Demonstration #1 (ATD-1). The ATD-1 Concept of Operations (ConOps) demonstration will integrate three NASA technologies to achieve high throughput, fuel-efficient arrival operations into busy terminal airspace. They are Traffic Management Advisor with Terminal Metering (TMA-TM) for precise time-based schedules to the runway and points within the terminal area, Controller-Managed Spacing (CMS) decision support tools for terminal controllers to better manage aircraft delay using speed control, and Flight deck Interval Management (FIM) avionics and flight crew procedures to conduct airborne spacing operations. The ATD-1 concept provides de-conflicted and efficient operations of multiple arrival streams of aircraft, passing through multiple merge points, from top-of-descent (TOD) to touchdown. It also enables aircraft to conduct Optimized Profile Descents (OPDs) from en route altitude to the runway, using primarily speed control to maintain separation and schedule. The ATD-1 project is currently addressing the challenges of integrating the three technologies, and implantation into an operational environment. Goals of the ATD-1 demonstration include increasing the throughput of high-density airports, reducing controller workload, increasing efficiency of arrival operations and the frequency of trajectory-based operations, and promoting aircraft ADS-B equipage.
Project W-320 acceptance test report for AY-farm electrical distribution
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bevins, R.R.
1998-04-02
This Acceptance Test Procedure (ATP) has been prepared to demonstrate that the AY-Farm Electrical Distribution System functions as required by the design criteria. This test is divided into three parts to support the planned construction schedule; Section 8 tests Mini-Power Pane AY102-PPI and the EES; Section 9 tests the SSS support systems; Section 10 tests the SSS and the Multi-Pak Group Control Panel. This test does not include the operation of end-use components (loads) supplied from the distribution system. Tests of the end-use components (loads) will be performed by other W-320 ATPs.
NASA Technical Reports Server (NTRS)
Sauerwein, Timothy A.; Gostomski, Thomas
2008-01-01
The ST5 technology demonstration mission led by GSFC of NASA's New Millennium Program managed by JPL consisted of three micro satellites (approximately 30 kg each) deployed into orbit from the Pegasus XL launch vehicle. In order to meet the launch date schedule of ST5, a different approach was required rather than the standard I&T approach used for single, room-sized satellites. The three spacecraft were designed, integrated, and tested at NASA Goddard Space Flight Center. It was determined that there was insufficient time in the schedule to perform three spacecraft I&T activities in series using standard approaches. The solution was for spacecraft #1 to undergo integration and test first, followed by spacecraft #2 and #3 simultaneously. This simultaneous integration was successful for several reasons. Each spacecraft had a Lead Test Conductor who planned and coordinated their spacecraft through its integration and test activities. One team of engineers and technicians executed the integration of all three spacecraft, learning and gaining knowledge and efficiency as spacecraft #1 integration and testing progressed. They became acutely familiar with the hardware, operation and processes for I&T, thus had the experience and knowledge to safely execute I&T for spacecraft #2 and #3. The integration team was extremely versatile; each member could perform many different activities or work any spacecraft, when needed. ST5 was successfully integrated, tested and shipped to the launch site per the I&T schedule that was planned three years previously. The I&T campaign was completed with ST5's successful launch on March 22, 2006.
Resistance to Change and Relapse of Observing
Thrailkill, Eric A; Shahan, Timothy A
2012-01-01
Four experiments examined relapse of extinguished observing behavior of pigeons using a two-component multiple schedule of observing-response procedures. In both components, unsignaled periods of variable-interval (VI) food reinforcement alternated with extinction and observing responses produced stimuli associated with the availability of the VI schedule (i.e., S+). The components differed in the rate of food arranged (Rich = VI 30 s; Lean = VI 120 s). In Experiment 1, following baseline training, extinction of observing involved removal of both food and S+ deliveries, and reinstatement was examined by presenting either response-independent food or S+ deliveries. In Experiment 2, extinction involved removal of only food deliveries while observing responses continued to produce S+. Reinstatement was examined by delivering food contingent upon the first two food-key responses occurring in the presence of the S+. Experiment 3 assessed ABA renewal of observing by extinguishing food-key and observing responses in the presence of one contextual stimulus (i.e., B) and then returning to the original training context (i.e., A) during continued extinction. Experiment 4 examined resurgence by introducing food reinforcement for an alternative response during extinction, and subsequently removing that alternative source of food. Across experiments, relative resistance to extinction and relapse of observing tended to be greater in the component previously associated with the higher rate of primary reinforcement. Relapse of observing or attending to stimuli associated with primary reinforcement appears to be impacted by frequency of primary reinforcement in a manner similar to responding maintained directly by primary reinforcement. PMID:22693359
Generation of Look-Up Tables for Dynamic Job Shop Scheduling Decision Support Tool
NASA Astrophysics Data System (ADS)
Oktaviandri, Muchamad; Hassan, Adnan; Mohd Shaharoun, Awaluddin
2016-02-01
Majority of existing scheduling techniques are based on static demand and deterministic processing time, while most job shop scheduling problem are concerned with dynamic demand and stochastic processing time. As a consequence, the solutions obtained from the traditional scheduling technique are ineffective wherever changes occur to the system. Therefore, this research intends to develop a decision support tool (DST) based on promising artificial intelligent that is able to accommodate the dynamics that regularly occur in job shop scheduling problem. The DST was designed through three phases, i.e. (i) the look-up table generation, (ii) inverse model development and (iii) integration of DST components. This paper reports the generation of look-up tables for various scenarios as a part in development of the DST. A discrete event simulation model was used to compare the performance among SPT, EDD, FCFS, S/OPN and Slack rules; the best performances measures (mean flow time, mean tardiness and mean lateness) and the job order requirement (inter-arrival time, due dates tightness and setup time ratio) which were compiled into look-up tables. The well-known 6/6/J/Cmax Problem from Muth and Thompson (1963) was used as a case study. In the future, the performance measure of various scheduling scenarios and the job order requirement will be mapped using ANN inverse model.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-12
...] Schedules of Controlled Substances: Temporary Placement of Three Synthetic Cannabinoids Into Schedule I... temporarily schedule three synthetic cannabinoids into the Controlled Substances Act (CSA) pursuant to the...). This action is based on a finding by the Deputy Administrator that the placement of these synthetic...
48 CFR 552.216-70 - Economic Price Adjustment-FSS Multiple Award Schedule Contracts.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Economic Price Adjustment... Text of Provisions and Clauses 552.216-70 Economic Price Adjustment—FSS Multiple Award Schedule Contracts. As prescribed in 516.203-4(a), insert the following clause: Economic Price Adjustment—FSS...
48 CFR 552.216-70 - Economic Price Adjustment-FSS Multiple Award Schedule Contracts.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Economic Price Adjustment... Text of Provisions and Clauses 552.216-70 Economic Price Adjustment—FSS Multiple Award Schedule Contracts. As prescribed in 516.203-4(a), insert the following clause: Economic Price Adjustment—FSS...
48 CFR 552.216-70 - Economic Price Adjustment-FSS Multiple Award Schedule Contracts.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Economic Price Adjustment... Text of Provisions and Clauses 552.216-70 Economic Price Adjustment—FSS Multiple Award Schedule Contracts. As prescribed in 516.203-4(a), insert the following clause: Economic Price Adjustment—FSS...
48 CFR 552.216-70 - Economic Price Adjustment-FSS Multiple Award Schedule Contracts.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Economic Price Adjustment... Text of Provisions and Clauses 552.216-70 Economic Price Adjustment—FSS Multiple Award Schedule Contracts. As prescribed in 516.203-4(a), insert the following clause: Economic Price Adjustment—FSS...
ERIC Educational Resources Information Center
Falcomata, Terry S.; Muething, Colin S.; Gainey, Summer; Hoffman, Katherine; Fragale, Christina
2013-01-01
We evaluated functional communication training (FCT) combined with a chained schedule of reinforcement procedure for the treatment of challenging behavior exhibited by two individuals diagnosed with Asperger syndrome and autism. Following functional analyses that suggested that challenging behavior served multiple functions for both participants,…
Phunchongharn, Phond; Hossain, Ekram; Camorlinga, Sergio
2011-11-01
We study the multiple access problem for e-Health applications (referred to as secondary users) coexisting with medical devices (referred to as primary or protected users) in a hospital environment. In particular, we focus on transmission scheduling and power control of secondary users in multiple spatial reuse time-division multiple access (STDMA) networks. The objective is to maximize the spectrum utilization of secondary users and minimize their power consumption subject to the electromagnetic interference (EMI) constraints for active and passive medical devices and minimum throughput guarantee for secondary users. The multiple access problem is formulated as a dual objective optimization problem which is shown to be NP-complete. We propose a joint scheduling and power control algorithm based on a greedy approach to solve the problem with much lower computational complexity. To this end, an enhanced greedy algorithm is proposed to improve the performance of the greedy algorithm by finding the optimal sequence of secondary users for scheduling. Using extensive simulations, the tradeoff in performance in terms of spectrum utilization, energy consumption, and computational complexity is evaluated for both the algorithms.
Devi, D Chitra; Uthariaraj, V Rhymend
2016-01-01
Cloud computing uses the concepts of scheduling and load balancing to migrate tasks to underutilized VMs for effectively sharing the resources. The scheduling of the nonpreemptive tasks in the cloud computing environment is an irrecoverable restraint and hence it has to be assigned to the most appropriate VMs at the initial placement itself. Practically, the arrived jobs consist of multiple interdependent tasks and they may execute the independent tasks in multiple VMs or in the same VM's multiple cores. Also, the jobs arrive during the run time of the server in varying random intervals under various load conditions. The participating heterogeneous resources are managed by allocating the tasks to appropriate resources by static or dynamic scheduling to make the cloud computing more efficient and thus it improves the user satisfaction. Objective of this work is to introduce and evaluate the proposed scheduling and load balancing algorithm by considering the capabilities of each virtual machine (VM), the task length of each requested job, and the interdependency of multiple tasks. Performance of the proposed algorithm is studied by comparing with the existing methods.
Devi, D. Chitra; Uthariaraj, V. Rhymend
2016-01-01
Cloud computing uses the concepts of scheduling and load balancing to migrate tasks to underutilized VMs for effectively sharing the resources. The scheduling of the nonpreemptive tasks in the cloud computing environment is an irrecoverable restraint and hence it has to be assigned to the most appropriate VMs at the initial placement itself. Practically, the arrived jobs consist of multiple interdependent tasks and they may execute the independent tasks in multiple VMs or in the same VM's multiple cores. Also, the jobs arrive during the run time of the server in varying random intervals under various load conditions. The participating heterogeneous resources are managed by allocating the tasks to appropriate resources by static or dynamic scheduling to make the cloud computing more efficient and thus it improves the user satisfaction. Objective of this work is to introduce and evaluate the proposed scheduling and load balancing algorithm by considering the capabilities of each virtual machine (VM), the task length of each requested job, and the interdependency of multiple tasks. Performance of the proposed algorithm is studied by comparing with the existing methods. PMID:26955656
Research on a Queue Scheduling Algorithm in Wireless Communications Network
NASA Astrophysics Data System (ADS)
Yang, Wenchuan; Hu, Yuanmei; Zhou, Qiancai
This paper proposes a protocol QS-CT, Queue Scheduling Mechanism based on Multiple Access in Ad hoc net work, which adds queue scheduling mechanism to RTS-CTS-DATA using multiple access protocol. By endowing different queues different scheduling mechanisms, it makes networks access to the channel much more fairly and effectively, and greatly enhances the performance. In order to observe the final performance of the network with QS-CT protocol, we simulate it and compare it with MACA/C-T without QS-CT protocol. Contrast to MACA/C-T, the simulation result shows that QS-CT has greatly improved the throughput, delay, rate of packets' loss and other key indicators.
Contextual Interference in Complex Bimanual Skill Learning Leads to Better Skill Persistence
Pauwels, Lisa; Swinnen, Stephan P.; Beets, Iseult A. M.
2014-01-01
The contextual interference (CI) effect is a robust phenomenon in the (motor) skill learning literature. However, CI has yielded mixed results in complex task learning. The current study addressed whether the CI effect is generalizable to bimanual skill learning, with a focus on the temporal evolution of memory processes. In contrast to previous studies, an extensive training schedule, distributed across multiple days of practice, was provided. Participants practiced three frequency ratios across three practice days following either a blocked or random practice schedule. During the acquisition phase, better overall performance for the blocked practice group was observed, but this difference diminished as practice progressed. At immediate and delayed retention, the random practice group outperformed the blocked practice group, except for the most difficult frequency ratio. Our main finding is that the random practice group showed superior performance persistence over a one week time interval in all three frequency ratios compared to the blocked practice group. This study contributes to our understanding of learning, consolidation and memory of complex motor skills, which helps optimizing training protocols in future studies and rehabilitation settings. PMID:24960171
Psychological Distance to Reward: Effects of S+ Duration and the Delay Reduction It Signals
ERIC Educational Resources Information Center
Alessandri, Jerome; Stolarz-Fantino, Stephanie; Fantino, Edmund
2011-01-01
A concurrent-chains procedure was used to examine choice between segmented (two-component chained schedules) and unsegmented schedules (simple schedules) in terminal links with equal inter-reinforcement intervals. Previous studies using this kind of experimental procedure showed preference for unsegmented schedules for both pigeons and humans. In…
Multiple Sclerosis: Molecular Mechanisms and Therapeutic Opportunities
Miljković, Djordje; Spasojević, Ivan
2013-01-01
Abstract The pathophysiology of multiple sclerosis (MS) involves several components: redox, inflammatory/autoimmune, vascular, and neurodegenerative. All of them are supported by the intertwined lines of evidence, and none of them should be written off. However, the exact mechanisms of MS initiation, its development, and progression are still elusive, despite the impressive pace by which the data on MS are accumulating. In this review, we will try to integrate the current facts and concepts, focusing on the role of redox changes and various reactive species in MS. Knowing the schedule of initial changes in pathogenic factors and the key turning points, as well as understanding the redox processes involved in MS pathogenesis is the way to enable MS prevention, early treatment, and the development of therapies that target specific pathophysiological components of the heterogeneous mechanisms of MS, which could alleviate the symptoms and hopefully stop MS. Pertinent to this, we will outline (i) redox processes involved in MS initiation; (ii) the role of reactive species in inflammation; (iii) prooxidative changes responsible for neurodegeneration; and (iv) the potential of antioxidative therapy. Antioxid. Redox Signal. 19, 2286–2334. PMID:23473637
Some Determinants of Remote Behavioral History Effects in Humans
ERIC Educational Resources Information Center
Hirai, Mariko; Okouchi, Hiroto; Matsumoto, Akio; Lattal, Kennon A.
2011-01-01
Undergraduates were exposed to a series of reinforcement schedules: first, to a fixed-ratio (FR) schedule in the presence of one stimulus and to a differential-reinforcement-of-low-rate (DRL) schedule in the presence of another (multiple FR DRL training), then to a fixed-interval (FI) schedule in the presence of a third stimulus (FI baseline),…
Thompson, Brennan J; Stock, Matt S; Banuelas, Victoria K
2017-05-01
Objective This study aimed to examine the effects of accumulating nursing work on maximal and rapid strength characteristics in female nurses and compare these effects in day versus night shift workers. Background Nurses exhibit among the highest nonfatal injury rates of all occupations, which may be a consequence of long, cumulative work shift schedules. Fatigue may accumulate across multiple shifts and lead to performance impairments, which in turn may be linked to injury risks. Method Thirty-seven nurses and aides performed isometric strength-based performance testing of three muscle groups, including the knee extensors, knee flexors, and wrist flexors (hand grip), as well as countermovement jumps, at baseline and following exposure to three 12-hour work shifts in a four-day period. Variables included peak torque (PT) and rate of torque development (RTD) from isometric strength testing and jump height and power output. Results The rigorous work period resulted in significant decreases (-7.2% to -19.2%) in a large majority (8/9) of the isometric strength-based measurements. No differences were noted for the day versus night shift workers except for the RTD at 200 millisecond variable, for which the night shift had greater work-induced decreases than the day shift workers. No changes were observed for jump height or power output. Conclusions A compressed nursing work schedule resulted in decreases in strength-based performance abilities, being indicative of performance fatigue. Application Compressed work schedules involving long shifts lead to functional declines in nurse performance capacities that may pose risks for both the nurse and patient quality of care. Fatigue management plans are needed to monitor and regulate increased levels of fatigue.
Resource management and scheduling policy based on grid for AIoT
NASA Astrophysics Data System (ADS)
Zou, Yiqin; Quan, Li
2017-07-01
This paper has a research on resource management and scheduling policy based on grid technology for Agricultural Internet of Things (AIoT). Facing the situation of a variety of complex and heterogeneous agricultural resources in AIoT, it is difficult to represent them in a unified way. But from an abstract perspective, there are some common models which can express their characteristics and features. Based on this, we proposed a high-level model called Agricultural Resource Hierarchy Model (ARHM), which can be used for modeling various resources. It introduces the agricultural resource modeling method based on this model. Compared with traditional application-oriented three-layer model, ARHM can hide the differences of different applications and make all applications have a unified interface layer and be implemented without distinction. Furthermore, it proposes a Web Service Resource Framework (WSRF)-based resource management method and the encapsulation structure for it. Finally, it focuses on the discussion of multi-agent-based AG resource scheduler, which is a collaborative service provider pattern in multiple agricultural production domains.
How do Air Traffic Controllers Use Automation and Tools Differently During High Demand Situations?
NASA Technical Reports Server (NTRS)
Kraut, Joshua M.; Mercer, Joey; Morey, Susan; Homola, Jeffrey; Gomez, Ashley; Prevot, Thomas
2013-01-01
In a human-in-the-loop simulation, two air traffic controllers managed identical airspace while burdened with higher than average workload, and while using advanced tools and automation designed to assist with scheduling aircraft on multiple arrival flows to a single meter fix. This paper compares the strategies employed by each controller, and investigates how the controllers' strategies change while managing their airspace under more normal workload conditions and a higher workload condition. Each controller engaged in different methods of maneuvering aircraft to arrive on schedule, and adapted their strategies to cope with the increased workload in different ways. Based on the conclusions three suggestions are made: that quickly providing air traffic controllers with recommendations and information to assist with maneuvering and scheduling aircraft when burdened with increased workload will improve the air traffic controller's effectiveness, that the tools should adapt to the strategy currently employed by a controller, and that training should emphasize which traffic management strategies are most effective given specific airspace demands.
Giebel, Ole; Wirtz, Anna; Nachreiner, Friedhelm
2008-04-01
In order to analyze whether impairments to health and well-being under flexible working hours can be predicted from specific characteristics of the work schedules, periodic components in flexible working hours and their interference with the circadian temperature rhythm were analyzed applying univariate and bivariate spectrum analyses to both time series. The resulting indicators of spectral power and phase shift of these components were then related to reported health impairments using regression analysis. The results show that a suppression of both the 24 and the 168 h components in the work schedules (i.e., a lack of periodicity) can be used to predict reported health impairments, and that if there are relatively strong 24 and 168 h components left in the work schedules, their phase difference with the temperature rhythm (as an indicator of the interference between working time and the circadian rhythm) further predicts impairment. The results indicate that the periodicity of working hours and the amount of (circadian) desynchronization induced by flexible work schedules can be used for predicting the impairing effects of flexible work schedules on health and well-being. The results can thus be used for evaluating and designing flexible shift rosters.
Enhanced Software for Scheduling Space-Shuttle Processing
NASA Technical Reports Server (NTRS)
Barretta, Joseph A.; Johnson, Earl P.; Bierman, Rocky R.; Blanco, Juan; Boaz, Kathleen; Stotz, Lisa A.; Clark, Michael; Lebovitz, George; Lotti, Kenneth J.; Moody, James M.;
2004-01-01
The Ground Processing Scheduling System (GPSS) computer program is used to develop streamlined schedules for the inspection, repair, and refurbishment of space shuttles at Kennedy Space Center. A scheduling computer program is needed because space-shuttle processing is complex and it is frequently necessary to modify schedules to accommodate unanticipated events, unavailability of specialized personnel, unexpected delays, and the need to repair newly discovered defects. GPSS implements constraint-based scheduling algorithms and provides an interactive scheduling software environment. In response to inputs, GPSS can respond with schedules that are optimized in the sense that they contain minimal violations of constraints while supporting the most effective and efficient utilization of space-shuttle ground processing resources. The present version of GPSS is a product of re-engineering of a prototype version. While the prototype version proved to be valuable and versatile as a scheduling software tool during the first five years, it was characterized by design and algorithmic deficiencies that affected schedule revisions, query capability, task movement, report capability, and overall interface complexity. In addition, the lack of documentation gave rise to difficulties in maintenance and limited both enhanceability and portability. The goal of the GPSS re-engineering project was to upgrade the prototype into a flexible system that supports multiple- flow, multiple-site scheduling and that retains the strengths of the prototype while incorporating improvements in maintainability, enhanceability, and portability.
A parallel computing engine for a class of time critical processes.
Nabhan, T M; Zomaya, A Y
1997-01-01
This paper focuses on the efficient parallel implementation of systems of numerically intensive nature over loosely coupled multiprocessor architectures. These analytical models are of significant importance to many real-time systems that have to meet severe time constants. A parallel computing engine (PCE) has been developed in this work for the efficient simplification and the near optimal scheduling of numerical models over the different cooperating processors of the parallel computer. First, the analytical system is efficiently coded in its general form. The model is then simplified by using any available information (e.g., constant parameters). A task graph representing the interconnections among the different components (or equations) is generated. The graph can then be compressed to control the computation/communication requirements. The task scheduler employs a graph-based iterative scheme, based on the simulated annealing algorithm, to map the vertices of the task graph onto a Multiple-Instruction-stream Multiple-Data-stream (MIMD) type of architecture. The algorithm uses a nonanalytical cost function that properly considers the computation capability of the processors, the network topology, the communication time, and congestion possibilities. Moreover, the proposed technique is simple, flexible, and computationally viable. The efficiency of the algorithm is demonstrated by two case studies with good results.
Drug discrimination under two concurrent fixed-interval fixed-interval schedules.
McMillan, D E; Li, M
2000-07-01
Pigeons were trained to discriminate 5.0 mg/kg pentobarbital from saline under a two-key concurrent fixed-interval (FI) 100-s FI 200-s schedule of food presentation, and later tinder a concurrent FI 40-s FI 80-s schedule, in which the FI component with the shorter time requirement reinforced responding on one key after drug administration (pentobarbital-biased key) and on the other key after saline administration (saline-biased key). After responding stabilized under the concurrent FI 100-s FI 200-s schedule, pigeons earned an average of 66% (after pentobarbital) to 68% (after saline) of their reinforcers for responding under the FI 100-s component of the concurrent schedule. These birds made an average of 70% of their responses on both the pentobarbital-biased key after the training dose of pentobarbital and the saline-biased key after saline. After responding stabilized under the concurrent FI 40-s FI 80-s schedule, pigeons earned an average of 67% of their reinforcers for responding under the FI 40 component after both saline and the training dose of pentobarbital. These birds made an average of 75% of their responses on the pentobarbital-biased key after the training dose of pentobarbital, but only 55% of their responses on the saline-biased key after saline. In test sessions preceded by doses of pentobarbital, chlordiazepoxide, ethanol, phencyclidine, or methamphetamine, the dose-response curves were similar under these two concurrent schedules. Pentobarbital, chlordiazepoxide, and ethanol produced dose-dependent increases in responding on the pentobarbital-biased key as the doses increased. For some birds, at the highest doses of these drugs, the dose-response curve turned over. Increasing doses of phencyclidine produced increased responding on the pentobarbital-biased key in some, but not all, birds. After methamphetamine, responding was largely confined to the saline-biased key. These data show that pigeons can perform drug discriminations under concurrent schedules in which the reinforcement frequency under the schedule components differs only by a factor of two, and that when other drugs are substituted for the training drugs they produce dose-response curves similar to the curves produced by these drugs under other concurrent interval schedules.
Integrating Microscopic Analysis into Existing Quality Assurance Processes
NASA Astrophysics Data System (ADS)
Frühberger, Peter; Stephan, Thomas; Beyerer, Jürgen
When technical goods, like mainboards and other electronic components, are produced, quality assurance (QA) is very important. To achieve this goal, different optical microscopes can be used to analyze a variety of specimen to gain comprehensive information by combining the acquired sensor data. In many industrial processes, cameras are used to examine these technical goods. Those cameras can analyze complete boards at once and offer a high level of accuracy when used for completeness checks. When small defects, e.g. soldered points, need to be examined in detail, those wide area cameras are limited. Microscopes with large magnification need to be used to analyze those critical areas. But microscopes alone cannot fulfill this task within a limited time schedule, because microscopic analysis of complete motherboards of a certain size is time demanding. Microscopes are limited concerning their depth of field and depth of focus, which is why additional components like XY moving tables need to be used to examine the complete surface. Yet today's industrial production quality standards require a 100 % control of the soldered components within a given time schedule. This level of quality, while keeping inspection time low, can only be achieved when combining multiple inspection devices in an optimized manner. This paper presents results and methods of combining industrial cameras with microscopy instrumenting a classificatory based approach intending to keep already deployed QA processes in place but extending them with the purpose of increasing the quality level of the produced technical goods while maintaining high throughput.
An Alternative to the Stay/Switch Equation Assessed When Using a Changeover-Delay
MacDonall, James S.
2015-01-01
An alternative to the generalized matching equation for understanding concurrent performances is the stay/switch model. For the stay/switch model, the important events are the contingencies and behaviors at each alternative. The current experiment compares the descriptions by two stay/switch equations, the original, empirically derived stay/switch equation and a more theoretically derived equation based on ratios of stay to switch responses matching ratios of stay to switch reinforcers. The present experiment compared descriptions by the original stay/switch equation when using and not using a changeover delay. It also compared descriptions by the more theoretical equation with and without a changeover delay. Finally, it compared descriptions of the concurrent performances by these two equations. Rats were trained in 15 conditions on identical concurrent random-interval schedules in each component of a multiple schedule. A COD operated in only one component. There were no consistent differences in the variance accounted for by each equation of concurrent performances whether or not a COD was used. The simpler equation found greater sensitivity to stay than to switch reinforcers. It also found a COD eliminated the influence of switch reinforcers. Because estimates of parameters were more meaningful when using the more theoretical stay/switch equation it is preferred. PMID:26299548
An alternative to the stay/switch equation assessed when using a changeover-delay.
MacDonall, James S
2015-11-01
An alternative to the generalized matching equation for understanding concurrent performances is the stay/switch model. For the stay/switch model, the important events are the contingencies and behaviors at each alternative. The current experiment compares the descriptions by two stay/switch equations, the original, empirically derived stay/switch equation and a more theoretically derived equation based on ratios of stay to switch responses matching ratios of stay to switch reinforcers. The present experiment compared descriptions by the original stay/switch equation when using and not using a changeover delay. It also compared descriptions by the more theoretical equation with and without a changeover delay. Finally, it compared descriptions of the concurrent performances by these two equations. Rats were trained in 15 conditions on identical concurrent random-interval schedules in each component of a multiple schedule. A COD operated in only one component. There were no consistent differences in the variance accounted for by each equation of concurrent performances whether or not a COD was used. The simpler equation found greater sensitivity to stay than to switch reinforcers. It also found a COD eliminated the influence of switch reinforcers. Because estimates of parameters were more meaningful when using the more theoretical stay/switch equation it is preferred. Copyright © 2015 Elsevier B.V. All rights reserved.
ERIC Educational Resources Information Center
Heald, M.; Allen, D.; Villa, D.; Oliver, C.
2013-01-01
This proof of principle study was designed to evaluate whether excessively high rates of social approach behaviors in children with Angelman syndrome (AS) can be modified using a multiple schedule design. Four children with AS were exposed to a multiple schedule arrangement, in which social reinforcement and extinction, cued using a novel…
ERIC Educational Resources Information Center
Torelli, Jessica N.; Lloyd, Blair P.; Diekman, Claire A.; Wehby, Joseph H.
2017-01-01
In elementary school classrooms, students commonly recruit teacher attention at inappropriately high rates or at inappropriate times. Multiple schedule interventions have been used to teach stimulus control by signaling to students when reinforcement is and is not available contingent on an appropriate response. The purpose of the current study…
Daniel I. Navon
1971-01-01
Timber RAM (Resource Allocation Method) is a long-range planning method for commercial timber lands under multiple-use management. Timber RAM can produce cutting and reforestation schedules and related harvest and economic reports. Each schedule optimizes an index of performance, subject to periodic constraints on revenues, costs, and, harvest levels. Periodic...
ERIC Educational Resources Information Center
Cammilleri, Anthony P.; Tiger, Jeffrey H.; Hanley, Gregory P.
2008-01-01
Children may recruit their teachers' attention at undesirably high rates or at inconvenient times. Tiger and Hanley (2004) described a multiple-schedule procedure to reduce ill-timed requests, which involved providing children with two distinct continuous signals that were correlated with periods in which teacher attention was either available or…
Hard real-time beam scheduler enables adaptive images in multi-probe systems
NASA Astrophysics Data System (ADS)
Tobias, Richard J.
2014-03-01
Real-time embedded-system concepts were adapted to allow an imaging system to responsively control the firing of multiple probes. Large-volume, operator-independent (LVOI) imaging would increase the diagnostic utility of ultrasound. An obstacle to this innovation is the inability of current systems to drive multiple transducers dynamically. Commercial systems schedule scanning with static lists of beams to be fired and processed; here we allow an imager to adapt to changing beam schedule demands, as an intelligent response to incoming image data. An example of scheduling changes is demonstrated with a flexible duplex mode two-transducer application mimicking LVOI imaging. Embedded-system concepts allow an imager to responsively control the firing of multiple probes. Operating systems use powerful dynamic scheduling algorithms, such as fixed priority preemptive scheduling. Even real-time operating systems lack the timing constraints required for ultrasound. Particularly for Doppler modes, events must be scheduled with sub-nanosecond precision, and acquired data is useless without this requirement. A successful scheduler needs unique characteristics. To get close to what would be needed in LVOI imaging, we show two transducers scanning different parts of a subjects leg. When one transducer notices flow in a region where their scans overlap, the system reschedules the other transducer to start flow mode and alter its beams to get a view of the observed vessel and produce a flow measurement. The second transducer does this in a focused region only. This demonstrates key attributes of a successful LVOI system, such as robustness against obstructions and adaptive self-correction.
Value of Conditioned Reinforcers as a Function of Temporal Context
ERIC Educational Resources Information Center
O'Daly, Matthew; Meyer, Steven; Fantino, Edmund
2005-01-01
In two experiments, pigeons were trained on a multiple-chain schedule, in which the initial link for one chain was a variable-interval (VI) 100s schedule and for the other chain a VI 10s schedule. The terminal links were both fixed-time 30s schedules signaled by differently colored stimuli. Following training, the pigeons had their preference for…
Swarm satellite mission scheduling & planning using Hybrid Dynamic Mutation Genetic Algorithm
NASA Astrophysics Data System (ADS)
Zheng, Zixuan; Guo, Jian; Gill, Eberhard
2017-08-01
Space missions have traditionally been controlled by operators from a mission control center. Given the increasing number of satellites for some space missions, generating a command list for multiple satellites can be time-consuming and inefficient. Developing multi-satellite, onboard mission scheduling & planning techniques is, therefore, a key research field for future space mission operations. In this paper, an improved Genetic Algorithm (GA) using a new mutation strategy is proposed as a mission scheduling algorithm. This new mutation strategy, called Hybrid Dynamic Mutation (HDM), combines the advantages of both dynamic mutation strategy and adaptive mutation strategy, overcoming weaknesses such as early convergence and long computing time, which helps standard GA to be more efficient and accurate in dealing with complex missions. HDM-GA shows excellent performance in solving both unconstrained and constrained test functions. The experiments of using HDM-GA to simulate a multi-satellite, mission scheduling problem demonstrates that both the computation time and success rate mission requirements can be met. The results of a comparative test between HDM-GA and three other mutation strategies also show that HDM has outstanding performance in terms of speed and reliability.
The relative effects on math performance of single- versus multiple-ratio schedules: a case study1
Lovitt, Tom C.; Esveldt, Karen A.
1970-01-01
This series of four experiments sought to assess the comparative effects of multiple- versus single-ratio schedules on a pupil's responding to mathematics materials. Experiment I, which alternated between single- and multiple-ratio contingencies, revealed that during the latter phase the subject responded at a higher rate. Similar findings were revealed by Exp. II. The third experiment, which manipulated frequency of reinforcement rather than multiple ratios, revealed that the alteration had a minimal effect on the subject's response rate. A final experiment, conducted to assess further the effects of multiple ratios, provided data similar to those of Exp. I and II. PMID:16795267
ERIC Educational Resources Information Center
Bilgi, Arzu Doganay; Özmen, E. Rüya
2018-01-01
This study investigates the effectiveness of Modified Multi-Component Cognitive Strategy Instruction (MMCSI) on expository text comprehension skills of students with mild intellectual disability (ID). Three students participated from inclusion classes of three different secondary schools in Turkey. The study was conducted using a multiple probe…
NASA Astrophysics Data System (ADS)
Liu, Yu-Che; Huang, Chung-Lin
2013-03-01
This paper proposes a multi-PTZ-camera control mechanism to acquire close-up imagery of human objects in a surveillance system. The control algorithm is based on the output of multi-camera, multi-target tracking. Three main concerns of the algorithm are (1) the imagery of human object's face for biometric purposes, (2) the optimal video quality of the human objects, and (3) minimum hand-off time. Here, we define an objective function based on the expected capture conditions such as the camera-subject distance, pan tile angles of capture, face visibility and others. Such objective function serves to effectively balance the number of captures per subject and quality of captures. In the experiments, we demonstrate the performance of the system which operates in real-time under real world conditions on three PTZ cameras.
2016-02-01
components. In 2010, they began an LEP to consolidate four versions of a legacy nuclear weapon, the B61 bomb , into a bomb called the B61-12 (see...Force Integrated Master Schedule BIMS Boeing Integrated Master Schedule B61 bomb B61 legacy bomb CD critical decision Cost Guide GAO Cost...are versions of the B61 bomb , an aircraft-delivered weapon that is a key component of the United States’ commitments to the North Atlantic Treaty
A General Cross-Layer Cloud Scheduling Framework for Multiple IoT Computer Tasks.
Wu, Guanlin; Bao, Weidong; Zhu, Xiaomin; Zhang, Xiongtao
2018-05-23
The diversity of IoT services and applications brings enormous challenges to improving the performance of multiple computer tasks' scheduling in cross-layer cloud computing systems. Unfortunately, the commonly-employed frameworks fail to adapt to the new patterns on the cross-layer cloud. To solve this issue, we design a new computer task scheduling framework for multiple IoT services in cross-layer cloud computing systems. Specifically, we first analyze the features of the cross-layer cloud and computer tasks. Then, we design the scheduling framework based on the analysis and present detailed models to illustrate the procedures of using the framework. With the proposed framework, the IoT services deployed in cross-layer cloud computing systems can dynamically select suitable algorithms and use resources more effectively to finish computer tasks with different objectives. Finally, the algorithms are given based on the framework, and extensive experiments are also given to validate its effectiveness, as well as its superiority.
Coordinated Science Campaign Scheduling for Sensor Webs
NASA Technical Reports Server (NTRS)
Edgington, Will; Morris, Robert; Dungan, Jennifer; Williams, Jenny; Carlson, Jean; Fleming, Damian; Wood, Terri; Yorke-Smith, Neil
2005-01-01
Future Earth observing missions will study different aspects and interacting pieces of the Earth's eco-system. Scientists are designing increasingly complex, interdisciplinary campaigns to exploit the diverse capabilities of multiple Earth sensing assets. In addition, spacecraft platforms are being configured into clusters, trains, or other distributed organizations in order to improve either the quality or the coverage of observations. These simultaneous advances in the design of science campaigns and in the missions that will provide the sensing resources to support them offer new challenges in the coordination of data and operations that are not addressed by current practice. For example, the scheduling of scientific observations for satellites in low Earth orbit is currently conducted independently by each mission operations center. An absence of an information infrastructure to enable the scheduling of coordinated observations involving multiple sensors makes it difficult to execute campaigns involving multiple assets. This paper proposes a software architecture and describes a prototype system called DESOPS (Distributed Earth Science Observation Planning and Scheduling) that will address this deficiency.
Multi-trip vehicle routing and scheduling problem with time window in real life
NASA Astrophysics Data System (ADS)
Sze, San-Nah; Chiew, Kang-Leng; Sze, Jeeu-Fong
2012-09-01
This paper studies a manpower scheduling problem with multiple maintenance operations and vehicle routing considerations. Service teams located at a common service centre are required to travel to different customer sites. All customers must be served within given time window, which are known in advance. The scheduling process must take into consideration complex constraints such as a meal break during the team's shift, multiple travelling trips, synchronisation of service teams and working shifts. The main objective of this study is to develop a heuristic that can generate high quality solution in short time for large problem instances. A Two-stage Scheduling Heuristic is developed for different variants of the problem. Empirical results show that the proposed solution performs effectively and efficiently. In addition, our proposed approximation algorithm is very flexible and can be easily adapted to different scheduling environments and operational requirements.
2017-03-23
PUBLIC RELEASE; DISTRIBUTION UNLIMITED Using Multiple and Logistic Regression to Estimate the Median Will- Cost and Probability of Cost and... Cost and Probability of Cost and Schedule Overrun for Program Managers Ryan C. Trudelle Follow this and additional works at: https://scholar.afit.edu...afit.edu. Recommended Citation Trudelle, Ryan C., "Using Multiple and Logistic Regression to Estimate the Median Will- Cost and Probability of Cost and
Cameron, Courtney M.; Wightman, R. Mark; Carelli, Regina M.
2014-01-01
Electrophysiological studies show that distinct subsets of nucleus accumbens (NAc) neurons differentially encode information about goal-directed behaviors for intravenous cocaine versus natural (food/water) rewards. Further, NAc rapid dopamine signaling occurs on a timescale similar to phasic cell firing during cocaine and natural reward-seeking behaviors. However, it is not known whether dopamine signaling is reinforcer specific (i.e., is released during responding for only one type of reinforcer) within discrete NAc locations, similar to neural firing dynamics. Here, fast-scan cyclic voltammetry (FSCV) was used to measure rapid dopamine release during multiple schedules involving sucrose reward and cocaine self-administration (n=8 rats) and, in a separate group of rats (n = 6), during a sucrose/food multiple schedule. During the sucrose/cocaine multiple schedule, dopamine increased within seconds of operant responding for both reinforcers. Although dopamine release was not reinforcer specific, more subtle differences were observed in peak dopamine concentration [DA] across reinforcer conditions. Specifically, peak [DA] was higher during the first phase of the multiple schedule, regardless of reinforcer type. Further, the time to reach peak [DA] was delayed during cocaine-responding compared to sucrose. During the sucrose/food multiple schedule, increases in dopamine release were also observed relative to operant responding for both natural rewards. However, peak [DA] was higher relative to responding for sucrose than food, regardless of reinforcer order. Overall, the results reveal the dynamics of rapid dopamine signaling in discrete locations in the NAc across reward conditions, and provide novel insight into the functional role of this system in reward-seeking behaviors. PMID:25174553
SSME component assembly and life management expert system
NASA Technical Reports Server (NTRS)
Ali, M.; Dietz, W. E.; Ferber, H. J.
1989-01-01
The space shuttle utilizes several rocket engine systems, all of which must function with a high degree of reliability for successful mission completion. The space shuttle main engine (SSME) is by far the most complex of the rocket engine systems and is designed to be reusable. The reusability of spacecraft systems introduces many problems related to testing, reliability, and logistics. Components must be assembled from parts inventories in a manner which will most effectively utilize the available parts. Assembly must be scheduled to efficiently utilize available assembly benches while still maintaining flight schedules. Assembled components must be assigned to as many contiguous flights as possible, to minimize component changes. Each component must undergo a rigorous testing program prior to flight. In addition, testing and assembly of flight engines and components must be done in conjunction with the assembly and testing of developmental engines and components. The development, testing, manufacture, and flight assignments of the engine fleet involves the satisfaction of many logistical and operational requirements, subject to many constraints. The purpose of the SSME Component Assembly and Life Management Expert System (CALMES) is to assist the engine assembly and scheduling process, and to insure that these activities utilize available resources as efficiently as possible.
ERIC Educational Resources Information Center
DeFulio, Anthony; Hackenberg, Timothy D.
2008-01-01
Pigeons pecked a response key on a variable-interval (VI) schedule, in which responses produced food every 40 s, on average. These VI periods, or components, alternated in irregular fashion with extinction components in which food was unavailable. Pecks on a second (observing) key briefly produced exteroceptive stimuli (houselight flashes)…
Guidelines for successful self-scheduling on nursing units.
Russell, Elizabeth; Hawkins, Jenna; Arnold, Kara A
2012-09-01
Self-scheduling programs are an increasingly popular strategy utilized by employers to address the individual and organizational challenges resulting from employee work-life imbalance among the nursing workforce. Certain key components will ensure buy-in and support from staff when self-scheduling programs are developed.
Diet components can suppress inflammation and reduce cancer risk.
Hardman, W Elaine
2014-06-01
Epidemiology studies indicate that diet or specific dietary components can reduce the risk for cancer, cardiovascular disease and diabetes. An underlying cause of these diseases is chronic inflammation. Dietary components that are beneficial against disease seem to have multiple mechanisms of action and many also have a common mechanism of reducing inflammation, often via the NFκB pathway. Thus, a plant based diet can contain many components that reduce inflammation and can reduce the risk for developing all three of these chronic diseases. We summarize dietary components that have been shown to reduce cancer risk and two studies that show that dietary walnut can reduce cancer growth and development. Part of the mechanism for the anticancer benefit of walnut was by suppressing the activation of NFκB. In this brief review, we focus on reduction of cancer risk by dietary components and the relationship to suppression of inflammation. However, it should be remembered that most dietary components have multiple beneficial mechanisms of action that can be additive and that suppression of chronic inflammation should reduce the risk for all three chronic diseases.
Diet components can suppress inflammation and reduce cancer risk
2014-01-01
Epidemiology studies indicate that diet or specific dietary components can reduce the risk for cancer, cardiovascular disease and diabetes. An underlying cause of these diseases is chronic inflammation. Dietary components that are beneficial against disease seem to have multiple mechanisms of action and many also have a common mechanism of reducing inflammation, often via the NFκB pathway. Thus, a plant based diet can contain many components that reduce inflammation and can reduce the risk for developing all three of these chronic diseases. We summarize dietary components that have been shown to reduce cancer risk and two studies that show that dietary walnut can reduce cancer growth and development. Part of the mechanism for the anticancer benefit of walnut was by suppressing the activation of NFκB. In this brief review, we focus on reduction of cancer risk by dietary components and the relationship to suppression of inflammation. However, it should be remembered that most dietary components have multiple beneficial mechanisms of action that can be additive and that suppression of chronic inflammation should reduce the risk for all three chronic diseases. PMID:24944766
ERIC Educational Resources Information Center
Ulke-Kurkcuoglu, Burcu; Bozkurt, Funda; Cuhadar, Selmin
2015-01-01
This study aims to investigate the effectiveness of the instruction process provided through computer-assisted activity schedules in the instruction of on-schedule and role-play skills to children with autism spectrum disorder. Herein, a multiple probe design with probe conditions across participants among single subject designs was used. Four…
Multivariate classification of small order watersheds in the Quabbin Reservoir Basin, Massachusetts
Lent, R.M.; Waldron, M.C.; Rader, J.C.
1998-01-01
A multivariate approach was used to analyze hydrologic, geologic, geographic, and water-chemistry data from small order watersheds in the Quabbin Reservoir Basin in central Massachusetts. Eighty three small order watersheds were delineated and landscape attributes defining hydrologic, geologic, and geographic features of the watersheds were compiled from geographic information system data layers. Principal components analysis was used to evaluate 11 chemical constituents collected bi-weekly for 1 year at 15 surface-water stations in order to subdivide the basin into subbasins comprised of watersheds with similar water quality characteristics. Three principal components accounted for about 90 percent of the variance in water chemistry data. The principal components were defined as a biogeochemical variable related to wetland density, an acid-neutralization variable, and a road-salt variable related to density of primary roads. Three subbasins were identified. Analysis of variance and multiple comparisons of means were used to identify significant differences in stream water chemistry and landscape attributes among subbasins. All stream water constituents were significantly different among subbasins. Multiple regression techniques were used to relate stream water chemistry to landscape attributes. Important differences in landscape attributes were related to wetlands, slope, and soil type.A multivariate approach was used to analyze hydrologic, geologic, geographic, and water-chemistry data from small order watersheds in the Quabbin Reservoir Basin in central Massachusetts. Eighty three small order watersheds were delineated and landscape attributes defining hydrologic, geologic, and geographic features of the watersheds were compiled from geographic information system data layers. Principal components analysis was used to evaluate 11 chemical constituents collected bi-weekly for 1 year at 15 surface-water stations in order to subdivide the basin into subbasins comprised of watersheds with similar water quality characteristics. Three principal components accounted for about 90 percent of the variance in water chemistry data. The principal components were defined as a biogeochemical variable related to wetland density, an acid-neutralization variable, and a road-salt variable related to density of primary roads. Three subbasins were identified. Analysis of variance and multiple comparisons of means were used to identify significant differences in stream water chemistry and landscape attributes among subbasins. All stream water constituents were significantly different among subbasins. Multiple regression techniques were used to relate stream water chemistry to landscape attributes. Important differences in landscape attributes were related to wetlands, slope, and soil type.
Steiner, Genevieve Z.; Barry, Robert J.; Gonsalvez, Craig J.
2016-01-01
In oddball tasks, increasing the time between stimuli within a particular condition (target-to-target interval, TTI; nontarget-to-nontarget interval, NNI) systematically enhances N1, P2, and P300 event-related potential (ERP) component amplitudes. This study examined the mechanism underpinning these effects in ERP components recorded from 28 adults who completed a conventional three-tone oddball task. Bivariate correlations, partial correlations and multiple regression explored component changes due to preceding ERP component amplitudes and intervals found within the stimulus series, rather than constraining the task with experimentally constructed intervals, which has been adequately explored in prior studies. Multiple regression showed that for targets, N1 and TTI predicted N2, TTI predicted P3a and P3b, and Processing Negativity (PN), P3b, and TTI predicted reaction time. For rare nontargets, P1 predicted N1, NNI predicted N2, and N1 predicted Slow Wave (SW). Findings show that the mechanism is operating on separate stages of stimulus-processing, suggestive of either increased activation within a number of stimulus-specific pathways, or very long component generator recovery cycles. These results demonstrate the extent to which matching-stimulus intervals influence ERP component amplitudes and behavior in a three-tone oddball task, and should be taken into account when designing similar studies. PMID:27445774
Steiner, Genevieve Z; Barry, Robert J; Gonsalvez, Craig J
2016-01-01
In oddball tasks, increasing the time between stimuli within a particular condition (target-to-target interval, TTI; nontarget-to-nontarget interval, NNI) systematically enhances N1, P2, and P300 event-related potential (ERP) component amplitudes. This study examined the mechanism underpinning these effects in ERP components recorded from 28 adults who completed a conventional three-tone oddball task. Bivariate correlations, partial correlations and multiple regression explored component changes due to preceding ERP component amplitudes and intervals found within the stimulus series, rather than constraining the task with experimentally constructed intervals, which has been adequately explored in prior studies. Multiple regression showed that for targets, N1 and TTI predicted N2, TTI predicted P3a and P3b, and Processing Negativity (PN), P3b, and TTI predicted reaction time. For rare nontargets, P1 predicted N1, NNI predicted N2, and N1 predicted Slow Wave (SW). Findings show that the mechanism is operating on separate stages of stimulus-processing, suggestive of either increased activation within a number of stimulus-specific pathways, or very long component generator recovery cycles. These results demonstrate the extent to which matching-stimulus intervals influence ERP component amplitudes and behavior in a three-tone oddball task, and should be taken into account when designing similar studies.
Unit Price and Choice in a Token-Reinforcement Context
ERIC Educational Resources Information Center
Foster, Theresa A.; Hackenberg, Timothy D.
2004-01-01
Pigeons were exposed to multiple and concurrent second-order schedules of token reinforcement, with stimulus lights serving as token reinforcers. Tokens were produced and exchanged for food according to various fixed-ratio schedules, yielding equal and unequal unit prices (responses per unit food delivery). On one schedule (termed the "standard…
Mousavi, Maryam; Yap, Hwa Jen; Musa, Siti Nurmaya; Tahriri, Farzad; Md Dawal, Siti Zawiah
2017-01-01
Flexible manufacturing system (FMS) enhances the firm's flexibility and responsiveness to the ever-changing customer demand by providing a fast product diversification capability. Performance of an FMS is highly dependent upon the accuracy of scheduling policy for the components of the system, such as automated guided vehicles (AGVs). An AGV as a mobile robot provides remarkable industrial capabilities for material and goods transportation within a manufacturing facility or a warehouse. Allocating AGVs to tasks, while considering the cost and time of operations, defines the AGV scheduling process. Multi-objective scheduling of AGVs, unlike single objective practices, is a complex and combinatorial process. In the main draw of the research, a mathematical model was developed and integrated with evolutionary algorithms (genetic algorithm (GA), particle swarm optimization (PSO), and hybrid GA-PSO) to optimize the task scheduling of AGVs with the objectives of minimizing makespan and number of AGVs while considering the AGVs' battery charge. Assessment of the numerical examples' scheduling before and after the optimization proved the applicability of all the three algorithms in decreasing the makespan and AGV numbers. The hybrid GA-PSO produced the optimum result and outperformed the other two algorithms, in which the mean of AGVs operation efficiency was found to be 69.4, 74, and 79.8 percent in PSO, GA, and hybrid GA-PSO, respectively. Evaluation and validation of the model was performed by simulation via Flexsim software.
Yap, Hwa Jen; Musa, Siti Nurmaya; Tahriri, Farzad; Md Dawal, Siti Zawiah
2017-01-01
Flexible manufacturing system (FMS) enhances the firm’s flexibility and responsiveness to the ever-changing customer demand by providing a fast product diversification capability. Performance of an FMS is highly dependent upon the accuracy of scheduling policy for the components of the system, such as automated guided vehicles (AGVs). An AGV as a mobile robot provides remarkable industrial capabilities for material and goods transportation within a manufacturing facility or a warehouse. Allocating AGVs to tasks, while considering the cost and time of operations, defines the AGV scheduling process. Multi-objective scheduling of AGVs, unlike single objective practices, is a complex and combinatorial process. In the main draw of the research, a mathematical model was developed and integrated with evolutionary algorithms (genetic algorithm (GA), particle swarm optimization (PSO), and hybrid GA-PSO) to optimize the task scheduling of AGVs with the objectives of minimizing makespan and number of AGVs while considering the AGVs’ battery charge. Assessment of the numerical examples’ scheduling before and after the optimization proved the applicability of all the three algorithms in decreasing the makespan and AGV numbers. The hybrid GA-PSO produced the optimum result and outperformed the other two algorithms, in which the mean of AGVs operation efficiency was found to be 69.4, 74, and 79.8 percent in PSO, GA, and hybrid GA-PSO, respectively. Evaluation and validation of the model was performed by simulation via Flexsim software. PMID:28263994
Automated Platform Management System Scheduling
NASA Technical Reports Server (NTRS)
Hull, Larry G.
1990-01-01
The Platform Management System was established to coordinate the operation of platform systems and instruments. The management functions are split between ground and space components. Since platforms are to be out of contact with the ground more than the manned base, the on-board functions are required to be more autonomous than those of the manned base. Under this concept, automated replanning and rescheduling, including on-board real-time schedule maintenance and schedule repair, are required to effectively and efficiently meet Space Station Freedom mission goals. In a FY88 study, we developed several promising alternatives for automated platform planning and scheduling. We recommended both a specific alternative and a phased approach to automated platform resource scheduling. Our recommended alternative was based upon use of exactly the same scheduling engine in both ground and space components of the platform management system. Our phased approach recommendation was based upon evolutionary development of the platform. In the past year, we developed platform scheduler requirements and implemented a rapid prototype of a baseline platform scheduler. Presently we are rehosting this platform scheduler rapid prototype and integrating the scheduler prototype into two Goddard Space Flight Center testbeds, as the ground scheduler in the Scheduling Concepts, Architectures, and Networks Testbed and as the on-board scheduler in the Platform Management System Testbed. Using these testbeds, we will investigate rescheduling issues, evaluate operational performance and enhance the platform scheduler prototype to demonstrate our evolutionary approach to automated platform scheduling. The work described in this paper was performed prior to Space Station Freedom rephasing, transfer of platform responsibility to Code E, and other recently discussed changes. We neither speculate on these changes nor attempt to predict the impact of the final decisions. As a consequence some of our work and results may be outdated when this paper is published.
The ILLIAC IV memory system: Current status and future possibilities
NASA Technical Reports Server (NTRS)
Stevenson, D. K.
1978-01-01
The future needs of researchers who will use the Illiac were examined and the requirements they will place on the memory system were evaluated. Various alternatives to replacing critical memory components were considered with regard to cost, risk, system impact, software requirements, and implementation schedules. The current system, its performance and status, and the limitations it places on possible enhancements are discussed as well as the planned enhancements to the Illiac processor. After a brief technology survey, different implementations are presented for each system memory component. Three different memory systems are proposed to meet the identified needs of the Illiac user community. These three alternatives differ considerably with respect to storage capacity and accessing capabilities, but they all offer significant improvements over the current system. The proposed systems and their relative merits are analyzed.
Íbias, Javier; Miguéns, Miguel; Pellón, Ricardo
2016-09-01
The spontaneously hypertensive rat (SHR) has been proposed as an animal model for attention deficit hyperactivity disorder (ADHD), and typically develops excessive patterns of response under most behavioural protocols. Schedule-induced polydipsia (SIP) is the excessive water consumption that occurs as a schedule effect when food is intermittently delivered and animals are partially food- but not water-deprived. SIP has been used as a model of excessive behaviour, and considerable evidence has involved the dopaminergic system in its development and maintenance. The aim of this study was to evaluate the effects of the most common psychostimulants used in ADHD treatment on SIP, comparing their effects in SHRs with rats from control populations. SHR, Wistar Kyoto (WKY) and Wistar rats were submitted to a multiple fixed time (FT) food schedule with two components: 30 s and 90 s. The acute effects of different dopaminergic compounds were evaluated after 40 sessions of SIP acquisition. All animals showed higher adjunctive drinking under FT 30 s than FT 90 s, and SHRs displayed higher asymptotic SIP levels in FT 90 s compared to WKY and Wistar rats. SHRs were less sensitive to dopaminergic agents than control rats in terms of affecting rates of adjunctive drinking. These differences point to an altered dopaminergic system in the SHR and provide new insights into the neurobiological basis of ADHD pharmacological treatments. © The Author(s) 2016.
Klarich, Mark J; Rea, Ronald W; Lal, Tarun Mohan; Garcia, Angel L; Steffens, Fay L
2016-01-01
Demand for ambulatory care visits is projected to increase 22% between 2008 and 2025. Given this growth, ambulatory care managers need to proactively plan for efficient use of scarce resources (ie, space, equipment, and staff). One important component of ambulatory care space (the number of examination rooms) is dependent on multiple factors, including variation in demand, hours of operation, scheduling, and staff. The authors (1) outline common data collection methods, (2) highlight analysis and reporting considerations for examination room utilization, and (3) provide a strategic framework for short- and long-term decision making for facility design or renovation.
Effects of a Single Night of Postpartum Sleep on Childless Women’s Daytime Functioning
McBean, Amanda L.; Kinsey, Steven G.; Montgomery-Downs, Hawley E.
2017-01-01
Study Objectives The maternal postpartum period is characterized by sleep fragmentation, which is associated with daytime impairment, mental health disturbances, and changes in melatonin patterns. In addition to sleep fragmentation, women undergo a complex set of physiological and environmental changes upon entering the postpartum period, confounding our understanding of effects of postpartum sleep disturbance. The primary study aim was to understand the basic impact of a single night of postpartum-like sleep fragmentation on sleep architecture, nocturnal melatonin levels, mood, daytime sleepiness, and neurobehavioral performance. Measurements and Results For one week prior to entry into the laboratory, eleven healthy nulliparous women kept a stable sleep-wake schedule (verified via actigraphy). Participants contributed three consecutive nights of laboratory overnight polysomnography: (1) a habituation/sleep disorder screening night; (2) a baseline night; and (3) a sleep fragmentation night, when participants were awakened three times for ~30 min each. Self-reported sleep quality and mood (Profile of Mood States Survey) both decreased significantly after sleep fragmentation compared to baseline measurements. Unexpectedly, daytime sleepiness (Multiple Sleep Latency Test) decreased significantly after sleep fragmentation. Experimental fragmentation had no significant effect on time spent in nocturnal sleep stages, urinary 6-sulphatoxymelatonin concentration, or psychomotor vigilance test performance. Participants continued to provide actigraphy data, and daily PVTs and self-reported sleep quality assessments at home for one week following sleep fragmentation; these assessments did not differ from baseline values. Conclusions While there were no changes in measured physiological components of a single night of postpartum-like experimental sleep fragmentation, there were decreases in self-reported measures of mood and sleep quality. Future research should examine the effects of multiple nights of modeling postpartum-like sleep fragmentation on objective measures of sleep and daytime functioning. PMID:26776447
NASA Astrophysics Data System (ADS)
Sembiring, N.; Ginting, E.; Darnello, T.
2017-12-01
Problems that appear in a company that produces refined sugar, the production floor has not reached the level of critical machine availability because it often suffered damage (breakdown). This results in a sudden loss of production time and production opportunities. This problem can be solved by Reliability Engineering method where the statistical approach to historical damage data is performed to see the pattern of the distribution. The method can provide a value of reliability, rate of damage, and availability level, of an machine during the maintenance time interval schedule. The result of distribution test to time inter-damage data (MTTF) flexible hose component is lognormal distribution while component of teflon cone lifthing is weibull distribution. While from distribution test to mean time of improvement (MTTR) flexible hose component is exponential distribution while component of teflon cone lifthing is weibull distribution. The actual results of the flexible hose component on the replacement schedule per 720 hours obtained reliability of 0.2451 and availability 0.9960. While on the critical components of teflon cone lifthing actual on the replacement schedule per 1944 hours obtained reliability of 0.4083 and availability 0.9927.
Evidence for Spiral Magnetic Structures at the Magnetopause: A Case for Multiple Reconnections
NASA Technical Reports Server (NTRS)
Vaisberg, O. L.; Smirnov, V. N.; Avanov, L. A.; Moore, T. E.
2003-01-01
We analyze plasma structures within the low latitude boundary layer (LLBL) observed by the lnterball Tail spacecraft under southward interplanetary magnetic field. Ion velocity distributions observed in the LLBL under these conditions fall into three categories: (a) D-shaped distributions, (b) ion velocity distributions consisting of two counterstreaming magnetosheath-type, and (c) distributions with three components where one of them has nearly zero velocity parallel to magnetic field (VlI), while the other two are counter-streaming components. D-shaped ion velocity distributions (a) correspond to magnetosheath plasma injections into reconnected flux tubes, as influenced by spacecraft location relative to the reconnection site. Simultaneous counter-streaming injections (b) suggest multiple reconnections. Three-component ion velocity distributions (c) and theii evolution with decreasing number density in the LLBL are consistent v behavior expected on long spiral flux tube islands at the magnetopaus as has been proposed and found to occur in magnetopause simulatior We interpret these distributions as a natural consequence of the formation of spiral magnetic flux tubes consisting of a mixture of alternating segments originating from the magnetosheath and magnetospheric plasmas. We suggest that multiple reconnections pla! an important role in the formation of the LLBL.
User’s guide to SNAP for ArcGIS® :ArcGIS interface for scheduling and network analysis program
Woodam Chung; Dennis Dykstra; Fred Bower; Stephen O’Brien; Richard Abt; John. and Sessions
2012-01-01
This document introduces a computer software named SNAP for ArcGIS® , which has been developed to streamline scheduling and transportation planning for timber harvest areas. Using modern optimization techniques, it can be used to spatially schedule timber harvest with consideration of harvesting costs, multiple products, alternative...
NASA Astrophysics Data System (ADS)
Foronda, Augusto; Ohta, Chikara; Tamaki, Hisashi
Dirty paper coding (DPC) is a strategy to achieve the region capacity of multiple input multiple output (MIMO) downlink channels and a DPC scheduler is throughput optimal if users are selected according to their queue states and current rates. However, DPC is difficult to implement in practical systems. One solution, zero-forcing beamforming (ZFBF) strategy has been proposed to achieve the same asymptotic sum rate capacity as that of DPC with an exhaustive search over the entire user set. Some suboptimal user group selection schedulers with reduced complexity based on ZFBF strategy (ZFBF-SUS) and proportional fair (PF) scheduling algorithm (PF-ZFBF) have also been proposed to enhance the throughput and fairness among the users, respectively. However, they are not throughput optimal, fairness and throughput decrease if each user queue length is different due to different users channel quality. Therefore, we propose two different scheduling algorithms: a throughput optimal scheduling algorithm (ZFBF-TO) and a reduced complexity scheduling algorithm (ZFBF-RC). Both are based on ZFBF strategy and, at every time slot, the scheduling algorithms have to select some users based on user channel quality, user queue length and orthogonality among users. Moreover, the proposed algorithms have to produce the rate allocation and power allocation for the selected users based on a modified water filling method. We analyze the schedulers complexity and numerical results show that ZFBF-RC provides throughput and fairness improvements compared to the ZFBF-SUS and PF-ZFBF scheduling algorithms.
Cameron, Courtney M; Wightman, R Mark; Carelli, Regina M
2014-11-01
Electrophysiological studies show that distinct subsets of nucleus accumbens (NAc) neurons differentially encode information about goal-directed behaviors for intravenous cocaine versus natural (food/water) rewards. Further, NAc rapid dopamine signaling occurs on a timescale similar to phasic cell firing during cocaine and natural reward-seeking behaviors. However, it is not known whether dopamine signaling is reinforcer specific (i.e., is released during responding for only one type of reinforcer) within discrete NAc locations, similar to neural firing dynamics. Here, fast-scan cyclic voltammetry (FSCV) was used to measure rapid dopamine release during multiple schedules involving sucrose reward and cocaine self-administration (n = 8 rats) and, in a separate group of rats (n = 6), during a sucrose/food multiple schedule. During the sucrose/cocaine multiple schedule, dopamine increased within seconds of operant responding for both reinforcers. Although dopamine release was not reinforcer specific, more subtle differences were observed in peak dopamine concentration [DA] across reinforcer conditions. Specifically, peak [DA] was higher during the first phase of the multiple schedule, regardless of reinforcer type. Further, the time to reach peak [DA] was delayed during cocaine-responding compared to sucrose. During the sucrose/food multiple schedule, increases in dopamine release were also observed relative to operant responding for both natural rewards. However, peak [DA] was higher relative to responding for sucrose than food, regardless of reinforcer order. Overall, the results reveal the dynamics of rapid dopamine signaling in discrete locations in the NAc across reward conditions, and provide novel insight into the functional role of this system in reward-seeking behaviors. Copyright © 2014 Elsevier Ltd. All rights reserved.
Vehicle coordinated transportation dispatching model base on multiple crisis locations
NASA Astrophysics Data System (ADS)
Tian, Ran; Li, Shanwei; Yang, Guoying
2018-05-01
Many disastrous events are often caused after unconventional emergencies occur, and the requirements of disasters are often different. It is difficult for a single emergency resource center to satisfy such requirements at the same time. Therefore, how to coordinate the emergency resources stored by multiple emergency resource centers to various disaster sites requires the coordinated transportation of emergency vehicles. In this paper, according to the problem of emergency logistics coordination scheduling, based on the related constraints of emergency logistics transportation, an emergency resource scheduling model based on multiple disasters is established.
Trade Study of Multiple Thruster Options for the Mars Airplane Concept
NASA Technical Reports Server (NTRS)
Kuhl, Christopher A.; Gayle, Steven W.; Hunter, Craig A.; Kenney, Patrick S.; Scola, Salvatore; Paddock, David A.; Wright, Henry S.; Gasbarre, Joseph F.
2009-01-01
A trade study was performed at NASA Langley Research Center under the Planetary Airplane Risk Reduction (PARR) project (2004-2005) to examine the option of using multiple, smaller thrusters in place of a single large thruster on the Mars airplane concept with the goal to reduce overall cost, schedule, and technical risk. The 5-lbf (22N) thruster is a common reaction control thruster on many satellites. Thousands of these types of thrusters have been built and flown on numerous programs, including MILSTAR and Intelsat VI. This study has examined the use of three 22N thrusters for the Mars airplane propulsion system and compared the results to those of the baseline single thruster system.
Link Scheduling Algorithm with Interference Prediction for Multiple Mobile WBANs
Le, Thien T. T.
2017-01-01
As wireless body area networks (WBANs) become a key element in electronic healthcare (e-healthcare) systems, the coexistence of multiple mobile WBANs is becoming an issue. The network performance is negatively affected by the unpredictable movement of the human body. In such an environment, inter-WBAN interference can be caused by the overlapping transmission range of nearby WBANs. We propose a link scheduling algorithm with interference prediction (LSIP) for multiple mobile WBANs, which allows multiple mobile WBANs to transmit at the same time without causing inter-WBAN interference. In the LSIP, a superframe includes the contention access phase using carrier sense multiple access with collision avoidance (CSMA/CA) and the scheduled phase using time division multiple access (TDMA) for non-interfering nodes and interfering nodes, respectively. For interference prediction, we define a parameter called interference duration as the duration during which disparate WBANs interfere with each other. The Bayesian model is used to estimate and classify the interference using a signal to interference plus noise ratio (SINR) and the number of neighboring WBANs. The simulation results show that the proposed LSIP algorithm improves the packet delivery ratio and throughput significantly with acceptable delay. PMID:28956827
Sensory mediation of stimulus-driven attentional capture in multiple-cue displays.
Wright, Richard D; Richard, Christian M
2003-08-01
Three location-cuing experiments were conducted in order to examine the stimulus-driven control of attentional capture in multiple-cue displays. These displays consisted of one to four simultaneously presented direct location cues. The results indicated that direct location cuing can produce cue effects that are mediated, in part, by nonattentional processing that occurs simultaneously at multiple locations. When single cues were presented in isolation, however, the resulting cue effect appeared to be due to a combination of sensory processing and attentional capture by the cue. This suggests that the faster responses produced by direct cues may be associated with two different components: an attention-related component that can be modulated by goal-driven factors and a nonattentional component that occurs in parallel at multiple direct-cue locations and is minimally affected by goal-driven factors.
NASA Astrophysics Data System (ADS)
Pyne, Moinak
This thesis aspires to model and control, the flow of power in a DC microgrid. Specifically, the energy sources are a photovoltaic system and the utility grid, a lead acid battery based energy storage system and twenty PEV charging stations as the loads. Theoretical principles of large scale state space modeling are applied to model the considerable number of power electronic converters needed for controlling voltage and current thresholds. The energy storage system is developed using principles of neural networks to facilitate a stable and uncomplicated model of the lead acid battery. Power flow control is structured as a hierarchical problem with multiple interactions between individual components of the microgrid. The implementation is done using fuzzy logic with scheduling the maximum use of available solar energy and compensating demand or excess power with the energy storage system, and minimizing utility grid use, while providing multiple speeds of charging the PEVs.
NASA Astrophysics Data System (ADS)
Kuai, Zi-Xiang; Liu, Wan-Yu; Zhu, Yue-Min
2017-11-01
The aim of this work was to investigate the effect of multiple perfusion components on the pseudo-diffusion coefficient D * in the bi-exponential intravoxel incoherent motion (IVIM) model. Simulations were first performed to examine how the presence of multiple perfusion components influences D *. The real data of livers (n = 31), spleens (n = 31) and kidneys (n = 31) of 31 volunteers was then acquired using DWI for in vivo study and the number of perfusion components in these tissues was determined together with their perfusion fraction and D *, using an adaptive multi-exponential IVIM model. Finally, the bi-exponential model was applied to the real data and the mean, standard variance and coefficient of variation of D * as well as the fitting residual were calculated over the 31 volunteers for each of the three tissues and compared between them. The results of both the simulations and the in vivo study showed that, for the bi-exponential IVIM model, both the variance of D * and the fitting residual tended to increase when the number of perfusion components was increased or when the difference between perfusion components became large. In addition, it was found that the kidney presented the fewest perfusion components among the three tissues. The present study demonstrated that multi-component perfusion is a main factor that causes high variance of D * and the bi-exponential model should be used only when the tissues under investigation have few perfusion components, for example the kidney.
Time-dependent contrast effects in a multiple schedule of food reinforcement1
Bernheim, Joseph W.; Williams, David R.
1967-01-01
Four rats were rewarded for running in a wheel under two alternating conditions of food reinforcement. These periods of frequent and infrequent reinforcement, each accompanied by a particular stimulus, were presented a number of times in each daily session. Following shifts from high to low frequency of reinforcement, responding decreased suddenly and markedly, and then recovered within the next few minutes. The magnitude of this temporary depression was an increasing function of the duration of the immediately preceding component of high-frequency reinforcement. A transient elevation in performance, which did not vary with the duration of the prior component, was noted in two subjects following shifts from low to high frequency of reinforcement. The elevation and depression effects did not appear simultaneously during the 48 experimental sessions. A possible relation between the difficulty of the discrimination and the extent of contrast effects is discussed. PMID:6056797
Special Inspector General for Iraq Reconstruction
2012-10-30
security facilities at Umm Qasr slipped three months.227 Because these upgrades might not be completed until aft er the OSC-I sites are transitioned...Basrah 11/18/2011 1/23/2013 1.1 0.6 0.5 Procure Electrical Coil Winding Machines Multiple 7/26/2012 11/23/2012 0.7 – 0.7 PHC Repairs in Central Iraq...complex in Baghdad continued to be the second-largest ongo- ing project. Once again, the schedule slipped . In April, USACE reported that it expected the
Choice with frequently changing food rates and food ratios.
Baum, William M; Davison, Michael
2014-03-01
In studies of operant choice, when one schedule of a concurrent pair is varied while the other is held constant, the constancy of the constant schedule may exert discriminative control over performance. In our earlier experiments, schedules varied reciprocally across components within sessions, so that while food ratio varied food rate remained constant. In the present experiment, we held one variable-interval (VI) schedule constant while varying the concurrent VI schedule within sessions. We studied five conditions, each with a different constant left VI schedule. On the right key, seven different VI schedules were presented in seven different unsignaled components. We analyzed performances at several different time scales. At the longest time scale, across conditions, behavior ratios varied with food ratios as would be expected from the generalized matching law. At shorter time scales, effects due to holding the left VI constant became more and more apparent, the shorter the time scale. In choice relations across components, preference for the left key leveled off as the right key became leaner. Interfood choice approximated strict matching for the varied right key, whereas interfood choice hardly varied at all for the constant left key. At the shortest time scale, visit patterns differed for the left and right keys. Much evidence indicated the development of a fix-and-sample pattern. In sum, the procedural difference made a large difference to performance, except for choice at the longest time scale and the fix-and-sample pattern at the shortest time scale. © Society for the Experimental Analysis of Behavior.
PLAN-IT-2: The next generation planning and scheduling tool
NASA Technical Reports Server (NTRS)
Eggemeyer, William C.; Cruz, Jennifer W.
1990-01-01
PLAN-IT is a scheduling program which has been demonstrated and evaluated in a variety of scheduling domains. The capability enhancements being made for the next generation of PLAN-IT, called PLAN-IT-2 is discussed. PLAN-IT-2 represents a complete rewrite of the original PLAN-IT incorporating major changes as suggested by the application experiences with the original PLAN-IT. A few of the enhancements described are additional types of constraints, such as states and resettable-depletables (batteries), dependencies between constraints, multiple levels of activity planning during the scheduling process, pattern constraint searching for opportunities as opposed to just minimizing the amount of conflicts, additional customization construction features for display and handling of diverse multiple time systems, and reduction in both the size and the complexity for creating the knowledge-base to address the different problem domains.
A customizable, scalable scheduling and reporting system.
Wood, Jody L; Whitman, Beverly J; Mackley, Lisa A; Armstrong, Robert; Shotto, Robert T
2014-06-01
Scheduling is essential for running a facility smoothly and for summarizing activities in use reports. The Penn State Hershey Clinical Simulation Center has developed a scheduling interface that uses off-the-shelf components, with customizations that adapt to each institution's data collection and reporting needs. The system is designed using programs within the Microsoft Office 2010 suite. Outlook provides the scheduling component, while the reporting is performed using Access or Excel. An account with a calendar is created for the main schedule, with separate resource accounts created for each room within the center. The Outlook appointment form's 2 default tabs are used, in addition to a customized third tab. The data are then copied from the calendar into either a database table or a spreadsheet, where the reports are generated.Incorporating this system into an institution-wide structure allows integration of personnel lists and potentially enables all users to check the schedule from their desktop. Outlook also has a Web-based application for viewing the basic schedule from outside the institution, although customized data cannot be accessed. The scheduling and reporting functions have been used for a year at the Penn State Hershey Clinical Simulation Center. The schedule has increased workflow efficiency, improved the quality of recorded information, and provided more accurate reporting. The Penn State Hershey Clinical Simulation Center's scheduling and reporting system can be adapted easily to most simulation centers and can expand and change to meet future growth with little or no expense to the center.
Vehicle Test Procedure Driving Schedules
DOT National Transportation Integrated Search
1977-03-01
This report discusses the salient characteristics of driving schedules which are currently being used to determine automotive fuel economy, exhaust emissions, and component characteristics. The analyses discussed and the results reported highlight th...
Complex ambulatory settings demand scheduling systems.
Ross, K M
1998-01-01
Practice management systems are becoming more and more complex, as they are asked to integrate all aspects of patient and resource management. Although patient scheduling is a standard expectation in any ambulatory environment, facilities and equipment resource scheduling are additional functionalities of scheduling systems. Because these functions were not typically managed in manual patient scheduling, often the result was resource mismanagement, along with a potential negative impact on utilization, patient flow and provider productivity. As ambulatory organizations have become more seasoned users of practice management software, the value of resource scheduling has become apparent. Appointment scheduling within a fully integrated practice management system is recognized as an enhancement of scheduling itself and provides additional tools to manage other information needs. Scheduling, as one component of patient information management, provides additional tools in these areas.
Technology for aircraft energy efficiency
NASA Technical Reports Server (NTRS)
Klineberg, J. M.
1977-01-01
Six technology programs for reducing fuel use in U.S. commercial aviation are discussed. The six NASA programs are divided into three groups: Propulsion - engine component improvement, energy efficient engine, advanced turboprops; Aerodynamics - energy efficient transport, laminar flow control; and Structures - composite primary structures. Schedules, phases, and applications of these programs are considered, and it is suggested that program results will be applied to current transport derivatives in the early 1980s and to all-new aircraft of the late 1980s and early 1990s.
JSC Wireless Sensor Network Update
NASA Technical Reports Server (NTRS)
Wagner, Robert
2010-01-01
Sensor nodes composed of three basic components... radio module: COTS radio module implementing standardized WSN protocol; treated as WSN modem by main board main board: contains application processor (TI MSP430 microcontroller), memory, power supply; responsible for sensor data acquisition, pre-processing, and task scheduling; re-used in every application with growing library of embedded C code sensor card: contains application-specific sensors, data conditioning hardware, and any advanced hardware not built into main board (DSPs, faster A/D, etc.); requires (re-) development for each application.
Real association of factors with inappropriate hospital days.
Huet, Bernard; Cauterman, Maxime
2005-01-01
Several studies of inappropriate (in the sense of the AEP) hospital days highlighted associations between two factors (rate of inappropriateness and reasons for inappropriateness, rate of inappropriateness and appropriate setting of care,..). The aim of this communication is to present a study on real associations, at constant factor, between five factors associated with hospital inappropriate days: medical management process, reason for inappropriateness, scheduled admission, rate of inappropriateness, length of stay. We used the European version of Appropriateness Evaluation Protocol for evaluation of inappropriate days and the French protocol ;for analysis of inappropriate days. The study set in three Parisian hospitals, four clinical departments, three specialities. 523 patients were included in the study, 5663 days were evaluated on a wide variety of pathologies: 27 Medical Management Processes. Results show that there are real associations (elimination of transitive associations) between five factors : medical management process and discharge processes, reason for inappropriateness, scheduled admission, rate of inappropriate days, length of stay. Multiple Correspondence Analysis on all "groups of contiguous days related with the same reason for inappropriateness" shows five profiles of queues integrating various medical management processes.
Kuria, Ng'endo; Reid, Anthony; Owiti, Philip; Tweya, Hannock; Kibet, Caleb Kipkurui; Mbau, Lilian; Manzi, Marcel; Murunga, Victor; Namusonge, Tecla; Kibachio, Joseph
2018-05-19
To determine and compare, among three models of care, compliance to scheduled clinic appointments and adherence to anti-hypertensive medication of patients in an informal settlement of Kibera, Kenya. Routinely collected patient data were used from three health facilities, six walkway clinics and one weekend/church clinic. Patients were eligible if they had received hypertension care for more than six months. Compliance with clinic appointments and self-reported adherence to medication were determined from clinic records and compared using the Chi-square test. Univariate and multivariate logistic regression models estimated the odds of overall adherence to medication. 785 patients received hypertension treatment eligible for analysis, of whom two-thirds were women. Between them, there were 5879 clinic visits with an overall compliance to appointments of 63%. Compliance was high in the health facilities and walkway clinics but men were more likely to attend the weekend/church clinics. Self-reported adherence to medication by those complying with scheduled clinic visits was 94%. Patients in the walkway clinics were two times more likely to adhere to anti-hypertensive medication than patients at the health facility (OR 1.97, 95%CI 1.25-3.10). Walkway clinics outperformed health facilities and weekend clinics. Use of multiple sites for the management of hypertensive patients led to good compliance with scheduled clinic visits and very good self-reported adherence to medication in a low-resource setting. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.
NASA Astrophysics Data System (ADS)
Arons-Polan, Bonnie
This study examined the effect of three schedule types on student achievement in Advanced Placement Biology classes. AP Biology test scores from students on three types of full-year schedules were analyzed to assess the impact schedule type had on student achievement. The three schedules included the block and traditional schedules, and the rotating/hybrid, a blend of the former two schedules. The results indicated the variable most closely associated with success on the AP Biology exam was the length of experience the teachers had teaching the course, regardless of schedule type. Although significant differences were seen in mean AP Biology test scores among the three schedule types, this could be explained by the relationship between instructors' experience and schedule type. Regression analysis determined the two strongest predictors of successful performance on the AP Biology exam were instructors' experience and perceived teaching style, regardless of schedule type. It appears that the economically developed suburbs, had teachers with the largest amount of experience teaching AP Biology, and these teachers reported using a direct approach to teaching, using lecture greater than 50% of the time. The results of this study also suggest when restructuring to improve student achievement, educators should examine other variables in addition to the high school schedule. Restructuring the day to allow for longer classes must be accompanied by professional staff development to allow teachers to develop new teaching methods. Most of the teachers in the survey reported using lecture a great deal of the time, regardless of schedule type. Comments from the teachers from the various schedules revealed that the ability to add student centered, inquiry based activities and labs were dependent on adequate class time. No information on whether or not the teachers were given professional development to expand their repertoire of teaching methods when the school adopted a block or rotating hybrid schedule was obtained. Limitations to this study include the fact that there was no independent verification of teaching style as reported by the teachers in this study. This study involved only Advanced Placement Biology classes, so no generalizations can be made to other science classes.
Multiple R&D projects scheduling optimization with improved particle swarm algorithm.
Liu, Mengqi; Shan, Miyuan; Wu, Juan
2014-01-01
For most enterprises, in order to win the initiative in the fierce competition of market, a key step is to improve their R&D ability to meet the various demands of customers more timely and less costly. This paper discusses the features of multiple R&D environments in large make-to-order enterprises under constrained human resource and budget, and puts forward a multi-project scheduling model during a certain period. Furthermore, we make some improvements to existed particle swarm algorithm and apply the one developed here to the resource-constrained multi-project scheduling model for a simulation experiment. Simultaneously, the feasibility of model and the validity of algorithm are proved in the experiment.
ERIC Educational Resources Information Center
Greve, Andrew W.
2017-01-01
The principal is ultimately responsible for decisions regarding the master schedule at the elementary level of education (Canady & Rettig, 2013; Young, 2008), and these scheduling decisions are influenced by multiple factors (Benamati, 2010; Harris, 2013; Howard & Rakoz, 2009). Although principals have become increasingly aware of the need…
Two-Level Scheduling for Video Transmission over Downlink OFDMA Networks
Tham, Mau-Luen
2016-01-01
This paper presents a two-level scheduling scheme for video transmission over downlink orthogonal frequency-division multiple access (OFDMA) networks. It aims to maximize the aggregate quality of the video users subject to the playback delay and resource constraints, by exploiting the multiuser diversity and the video characteristics. The upper level schedules the transmission of video packets among multiple users based on an overall target bit-error-rate (BER), the importance level of packet and resource consumption efficiency factor. Instead, the lower level renders unequal error protection (UEP) in terms of target BER among the scheduled packets by solving a weighted sum distortion minimization problem, where each user weight reflects the total importance level of the packets that has been scheduled for that user. Frequency-selective power is then water-filled over all the assigned subcarriers in order to leverage the potential channel coding gain. Realistic simulation results demonstrate that the proposed scheme significantly outperforms the state-of-the-art scheduling scheme by up to 6.8 dB in terms of peak-signal-to-noise-ratio (PSNR). Further test evaluates the suitability of equal power allocation which is the common assumption in the literature. PMID:26906398
48 CFR 552.238-71 - Submission and Distribution of Authorized FSS Schedule Pricelists.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Multiple Award Schedule electronic data base. (d) The Contractor shall make all of the distributions... electronic submission with the award notification. Some structured data entry in a prescribed format may be...
48 CFR 552.238-71 - Submission and Distribution of Authorized FSS Schedule Pricelists.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Multiple Award Schedule electronic data base. (d) The Contractor shall make all of the distributions... electronic submission with the award notification. Some structured data entry in a prescribed format may be...
48 CFR 552.238-71 - Submission and Distribution of Authorized FSS Schedule Pricelists.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Multiple Award Schedule electronic data base. (d) The Contractor shall make all of the distributions... electronic submission with the award notification. Some structured data entry in a prescribed format may be...
48 CFR 552.238-71 - Submission and Distribution of Authorized FSS Schedule Pricelists.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Multiple Award Schedule electronic data base. (d) The Contractor shall make all of the distributions... electronic submission with the award notification. Some structured data entry in a prescribed format may be...
48 CFR 552.238-71 - Submission and Distribution of Authorized FSS Schedule Pricelists.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Multiple Award Schedule electronic data base. (d) The Contractor shall make all of the distributions... electronic submission with the award notification. Some structured data entry in a prescribed format may be...
Deep space network resource scheduling approach and application
NASA Technical Reports Server (NTRS)
Eggemeyer, William C.; Bowling, Alan
1987-01-01
Deep Space Network (DSN) resource scheduling is the process of distributing ground-based facilities to track multiple spacecraft. The Jet Propulsion Laboratory has carried out extensive research to find ways of automating this process in an effort to reduce time and manpower costs. This paper presents a resource-scheduling system entitled PLAN-IT with a description of its design philosophy. The PLAN-IT's current on-line usage and limitations in scheduling the resources of the DSN are discussed, along with potential enhancements for DSN application.
2015-05-28
Diver Characteristics Appendix E Diving Schedule Appendix F Medical Incidents Appendix G UBA Gas Compositions iv ACKNOWLEDGEMENTS The...experimental dives (median = 3). The schedule of each diver’s participation in experimental dives is given in Appendix E . Divers were required to avoid any...divers’ participation on each test schedule is given in Appendix E . The numbers of completed man-dives on the two schedules are not multiples of the
Preliminary design report for OTEC stationkeeping subsystems (SKSS)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1979-12-12
Lockheed Ocean Systems with IMODCO prepared these preliminary designs for OTEC Stationkeeping Subsystems (SKSS) under contract to NOAA in support of the Department of Energy OTEC program. The results of Tasks III, V, and VI are presented in this design report. The report consists of five sections: introduction, preliminary designs for the multiple anchor leg (MAL) and tension anchor leg (TAL), costs and schedule, and conclusions. Extensive appendixes provide detailed descriptions of design methodology and include backup calculations and data to support the results presented. The objective of this effort is to complete the preliminary designs for the barge-MAL andmore » Spar-TAL SKSS. A set of drawings is provided for each which show arrangements, configuration, component details, engineering description, and deployment plan. Loads analysis, performance assessment, and sensitivity to requirements are presented, together with the methodology employed to analyze the systems and to derive the results presented. Life cycle costs and schedule are prepared and compared on a common basis. Finally, recommendations for the Commercial Plant SKSS are presented for both platform types.« less
Effects of restricted feeding schedules on circadian organization in squirrel monkeys
NASA Technical Reports Server (NTRS)
Boulos, Z.; Frim, D. M.; Dewey, L. K.; Moore-Ede, M. C.
1989-01-01
Free running circadian rhythms of motor activity, food-motivated lever-pressing, and either drinking (N = 7) or body temperature (N = 3) were recorded from 10 squirrel monkeys maintained in constant illumination with unlimited access to food. Food availability was then restricted to a single unsignaled 3-hour interval each day. The feeding schedule failed to entrain the activity rhythms of 8 monkeys, which continued to free-run. Drinking was almost completely synchronized by the schedule, while body temperature showed a feeding-induced rise superimposed on a free-running rhythm. Nonreinforced lever-pressing showed both a free-running component and a 24-hour component that anticipated the time of feeding. At the termination of the schedule, all recorded variables showed free-running rhythms, but in 3 animals the initial phase of the postschedule rhythms was advanced by several hours, suggesting relative coordination. Of the remaining 2 animals, one exhibited stable entrainment of all 3 recorded rhythms, while the other appeared to entrain temporarily to the feeding schedule. These results indicate that restricted feeding schedules are only a weak zeitgeber for the circadian pacemaker generating free-running rhythms in the squirrel monkey. Such schedules, however, may entrain a separate circadian system responsible for the timing of food-anticipatory changes in behavior and physiology.
Six components observations of local earthquakes during the 2016 Central Italy seismic sequence
NASA Astrophysics Data System (ADS)
Simonelli, A.; Bernauer, F.; Chow, B.; Braun, T.; Wassermann, J. M.; Igel, H.
2017-12-01
For many years the seismological community has looked for a reliable, sensitive, broadband three-component portable rotational sensor. In this preliminary study, we show the possibility of measuring and extracting relevant seismological information from local earthquakes. We employ portable three-component rotational sensors, insensitive to translations, which operate on optical interferometry principles (Sagnac effect). Multiple sensors recording redundantly add significance to the measurements.During the Central Italy seismic sequence in November 2016, we deployed two portable fiber-optic gyroscopes (BlueSeis3A from iXBlue and LCG demonstrator from LITEF) and a broadband seismometer in Colfiorito, Italy. We present here the six-component observations, with analysis of rotational (three redundant components) and translational (three components) ground motions, generated by earthquakes at local distances. For each seismic event, we compare coherence between rotational sensors and estimate a back azimuth consistent with theoretical values. We also estimate Love and Rayleigh wave phase velocities in the 5 to 10 Hz frequency range.
Multiple-Purpose Subsonic Naval Aircraft (MPSNA) Multiple Application Propfan Study (MAPS)
NASA Technical Reports Server (NTRS)
Winkeljohn, D. M.; Mayrand, C. H.
1986-01-01
A conceptual design study compared a selected propfan-powered aircraft to a turbofan-powered aircraft for multiple Navy carrier-based support missions in the 1995 timeframe. Conventional takeoff and landing (CTOL) propfan and turbofan-powered designs and short takeoff/vertical landing (STOVL) propfan-powered designs are presented. Ten support mission profiles were defined and the aircraft were sized to be able to perform all ten missions. Emphasis was placed on efficient high altitude loiter for Airborne Early Warning (AEW) and low altitude high speed capability for various offensive and tactical support missions. The results of the study show that the propfan-powered designs have lighter gross weights, lower fuel fractions, and equal or greater performance capability than the turbofan-powered designs. Various sensitives were developed in the study, including the effect of using single-rotation versus counter-rotation propfans and the effect of AEW loiter altitude on vehicle gross weight and empty weight. A propfan technology development plan was presented which illustrates that the development of key components can be achieved without accelerated schedules through the extension of current and planned government and civil propfan programs.
Strum, David P; May, Jerrold H; Sampson, Allan R; Vargas, Luis G; Spangler, William E
2003-01-01
Variability inherent in the duration of surgical procedures complicates surgical scheduling. Modeling the duration and variability of surgeries might improve time estimates. Accurate time estimates are important operationally to improve utilization, reduce costs, and identify surgeries that might be considered outliers. Surgeries with multiple procedures are difficult to model because they are difficult to segment into homogenous groups and because they are performed less frequently than single-procedure surgeries. The authors studied, retrospectively, 10,740 surgeries each with exactly two CPTs and 46,322 surgical cases with only one CPT from a large teaching hospital to determine if the distribution of dual-procedure surgery times fit more closely a lognormal or a normal model. The authors tested model goodness of fit to their data using Shapiro-Wilk tests, studied factors affecting the variability of time estimates, and examined the impact of coding permutations (ordered combinations) on modeling. The Shapiro-Wilk tests indicated that the lognormal model is statistically superior to the normal model for modeling dual-procedure surgeries. Permutations of component codes did not appear to differ significantly with respect to total procedure time and surgical time. To improve individual models for infrequent dual-procedure surgeries, permutations may be reduced and estimates may be based on the longest component procedure and type of anesthesia. The authors recommend use of the lognormal model for estimating surgical times for surgeries with two component procedures. Their results help legitimize the use of log transforms to normalize surgical procedure times prior to hypothesis testing using linear statistical models. Multiple-procedure surgeries may be modeled using the longest (statistically most important) component procedure and type of anesthesia.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yoginath, Srikanth B; Perumalla, Kalyan S; Henz, Brian J
2012-01-01
In prior work (Yoginath and Perumalla, 2011; Yoginath, Perumalla and Henz, 2012), the motivation, challenges and issues were articulated in favor of virtual time ordering of Virtual Machines (VMs) in network simulations hosted on multi-core machines. Two major components in the overall virtualization challenge are (1) virtual timeline establishment and scheduling of VMs, and (2) virtualization of inter-VM communication. Here, we extend prior work by presenting scaling results for the first component, with experiment results on up to 128 VMs scheduled in virtual time order on a single 12-core host. We also explore the solution space of design alternatives formore » the second component, and present performance results from a multi-threaded, multi-queue implementation of inter-VM network control for synchronized execution with VM scheduling, incorporated in our NetWarp simulation system.« less
Podlesnik, Christopher A; Fleet, James D
2014-09-01
Behavioral momentum theory asserts Pavlovian stimulus-reinforcer relations govern the persistence of operant behavior. Specifically, resistance to conditions of disruption (e.g., extinction, satiation) reflects the relation between discriminative stimuli and the prevailing reinforcement conditions. The present study assessed whether Pavlovian stimulus-reinforcer relations govern resistance to disruption in pigeons by arranging both response-dependent and -independent food reinforcers in two components of a multiple schedule. In one component, discrete-stimulus changes preceded response-independent reinforcers, paralleling methods that reduce Pavlovian conditioned responding to contextual stimuli. Compared to the control component with no added stimuli preceding response-independent reinforcement, response rates increased as discrete-stimulus duration increased (0, 5, 10, and 15 s) across conditions. Although resistance to extinction decreased as stimulus duration increased in the component with the added discrete stimulus, further tests revealed no effect of discrete stimuli, including other disrupters (presession food, intercomponent food, modified extinction) and reinstatement designed to control for generalization decrement. These findings call into question a straightforward conception that the stimulus-reinforcer relations governing resistance to disruption reflect the same processes as Pavlovian conditioning, as asserted by behavioral momentum theory. © Society for the Experimental Analysis of Behavior.
Thompson, Brennan J; Stock, Matt S; Banuelas, Victoria K; Akalonu, Chibuzo C
2016-07-01
The aim of this study was to determine the impact of a demanding work schedule involving long, cumulative work shifts on response time and balance-related performance outcomes and to evaluate the prevalence of musculoskeletal disorders between day and night shift working nurses. A questionnaire was used to identify the prevalence of past (12-month) and current (7-day) musculoskeletal disorders. Nurses worked three 12-hour work shifts in a 4-day period. Reaction time and balance tests were conducted before and after the work period. The work period induced impairments for reaction time, errors on reaction time tasks, and balance performance, independent of shift type. Musculoskeletal symptom prevalence was high in workers of both work shifts. Compressed work shifts caused performance-based fatigue in nurses. Reaction time and balance tests may be sensitive fatigue identification markers in nurses.
NASA Astrophysics Data System (ADS)
Sembiring, N.; Nasution, A. H.
2018-02-01
Corrective maintenance i.e replacing or repairing the machine component after machine break down always done in a manufacturing company. It causes the production process must be stopped. Production time will decrease due to the maintenance team must replace or repair the damage machine component. This paper proposes a preventive maintenance’s schedule for a critical component of a critical machine of an crude palm oil and kernel company due to increase maintenance efficiency. The Reliability Engineering & Maintenance Value Stream Mapping is used as a method and a tool to analize the reliability of the component and reduce the wastage in any process by segregating value added and non value added activities.
Multiple Power-Saving MSSs Scheduling Methods for IEEE802.16e Broadband Wireless Networks
2014-01-01
This work proposes two enhanced multiple mobile subscriber stations (MSSs) power-saving scheduling methods for IEEE802.16e broadband wireless networks. The proposed methods are designed for the Unsolicited Grant Service (UGS) of IEEE802.16e. To reduce the active periods of all power-saving MSSs, the base station (BS) allocates each MSS fewest possible transmission frames to retrieve its data from the BS. The BS interlaces the active periods of each MSS to increase the amount of scheduled MSSs and splits the overflowing transmission frames to maximize the bandwidth utilization. Simulation results reveal that interlacing the active periods of MSSs can increase the number of scheduled MSSs to more than four times of that in the Direct scheduling method. The bandwidth utilization can thus be improved by 60%–70%. Splitting the overflowing transmission frames can improve bandwidth utilization by more than 10% over that achieved using the method of interlacing active periods, with a sacrifice of only 1% of the sleep periods in the interlacing active period method. PMID:24523656
Dolan, Samantha B; Patel, Manish; Hampton, Lee M; Burnett, Eleanor; Ehlman, Daniel C; Garon, Julie; Cloessner, Emily; Chmielewski, Elizabeth; Hyde, Terri B; Mantel, Carsten; Wallace, Aaron S
2017-07-01
In 2013, the World Health Organization's (WHO's) Strategic Advisory Group of Experts (SAGE) recommended that all 126 countries using only oral polio vaccine (OPV) introduce at least 1 dose of inactivated polio vaccine (IPV) into their routine immunization schedules by the end of 2015. In many countries, the addition of IPV would necessitate delivery of multiple injectable vaccines (hereafter, "multiple injections") during a single visit, with infants receiving IPV alongside pentavalent vaccine (which covers diphtheria, tetanus, and whole-cell pertussis; hepatitis B; and Haemophilus influenzae type b) and pneumococcal vaccine. Unanticipated concerns emerged from countries over acceptability of multiple injections, sites of administration, and safety. We contextualized the issues surrounding multiple injections by documenting concerns associated with administration of ≥3 injections, existing evidence in the published literature, and findings of a systematic review on administration practices and techniques. Concerns associated with multiple-injection visits were documented from meetings and personal communications with immunization program managers. Published literature on the acceptability of multiple injections by providers and caregivers was summarized, and a systematic review of the literature on administration practices was completed on the following topics: spacing between injection sites (ie, vaccine spacing), site of injection, route of injection, and procedural preparedness. WHO and United Nations Children's Fund data from 2013-2015 were used to assess multiple-injection visits included in national immunization schedules. Healthcare provider and caregiver attitudes and practices indicated concerns about infant pain, potential adverse effects, and uncertainty about vaccine effectiveness with multiple-injection visits. Published literature reinforced the record of safety and acceptance of the recommended schedule of IPV by the SAGE, but the evidence was largely from developed countries. Parental acceptance of multiple injections was associated with a positive provider recommendation to the caregiver. Findings of the systematic review identified that the intramuscular route is preferred over the subcutaneous route for vaccine administration and that the vastus lateralis muscle is preferred over the deltoid muscle for intramuscular injections. Recommendations on vaccine spacing and procedural preparedness were based on practical necessities, but comparative evidence was not identified. During 2013-2015, 85 countries added IPV to their immunization schedules, 46 (55%) of which adopted a schedule resulting in 3 injectable vaccines being administered in a single visit. The multiple-injection experience identified gaps in guidance for future vaccine introductions. Global partner organizations quickly mobilized to assess, document, and communicate the existing global experience on multiple-injection visits. This evidence-based approach provided reassurance to opinion leaders, health workers, and professional societies, thus encouraging uptake of IPV as a second or third injection in an accelerated manner globally. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.
Patel, Manish; Hampton, Lee M.; Burnett, Eleanor; Ehlman, Daniel C.; Garon, Julie; Cloessner, Emily; Chmielewski, Elizabeth; Hyde, Terri B.; Mantel, Carsten; Wallace, Aaron S.
2017-01-01
Abstract Background. In 2013, the World Health Organization’s (WHO’s) Strategic Advisory Group of Experts (SAGE) recommended that all 126 countries using only oral polio vaccine (OPV) introduce at least 1 dose of inactivated polio vaccine (IPV) into their routine immunization schedules by the end of 2015. In many countries, the addition of IPV would necessitate delivery of multiple injectable vaccines (hereafter, “multiple injections”) during a single visit, with infants receiving IPV alongside pentavalent vaccine (which covers diphtheria, tetanus, and whole-cell pertussis; hepatitis B; and Haemophilus influenzae type b) and pneumococcal vaccine. Unanticipated concerns emerged from countries over acceptability of multiple injections, sites of administration, and safety. We contextualized the issues surrounding multiple injections by documenting concerns associated with administration of ≥3 injections, existing evidence in the published literature, and findings of a systematic review on administration practices and techniques. Methods. Concerns associated with multiple-injection visits were documented from meetings and personal communications with immunization program managers. Published literature on the acceptability of multiple injections by providers and caregivers was summarized, and a systematic review of the literature on administration practices was completed on the following topics: spacing between injection sites (ie, vaccine spacing), site of injection, route of injection, and procedural preparedness. WHO and United Nations Children’s Fund data from 2013–2015 were used to assess multiple-injection visits included in national immunization schedules. Results. Healthcare provider and caregiver attitudes and practices indicated concerns about infant pain, potential adverse effects, and uncertainty about vaccine effectiveness with multiple-injection visits. Published literature reinforced the record of safety and acceptance of the recommended schedule of IPV by the SAGE, but the evidence was largely from developed countries. Parental acceptance of multiple injections was associated with a positive provider recommendation to the caregiver. Findings of the systematic review identified that the intramuscular route is preferred over the subcutaneous route for vaccine administration and that the vastus lateralis muscle is preferred over the deltoid muscle for intramuscular injections. Recommendations on vaccine spacing and procedural preparedness were based on practical necessities, but comparative evidence was not identified. During 2013–2015, 85 countries added IPV to their immunization schedules, 46 (55%) of which adopted a schedule resulting in 3 injectable vaccines being administered in a single visit. Conclusion. The multiple-injection experience identified gaps in guidance for future vaccine introductions. Global partner organizations quickly mobilized to assess, document, and communicate the existing global experience on multiple-injection visits. This evidence-based approach provided reassurance to opinion leaders, health workers, and professional societies, thus encouraging uptake of IPV as a second or third injection in an accelerated manner globally. PMID:28838188
Sidana, Surbhi; Narkhede, Mayur; Elson, Paul; Hastings, Debbie; Faiman, Beth; Valent, Jason; Samaras, Christy; Hamilton, Kimberly; Liu, Hien K.; Smith, Mitchell R.; Reu, Frederic J.
2017-01-01
Introduction Randomized studies have shown that bortezomib (BTZ) can be given weekly via intravenous (IV) route or twice weekly via subcutaneous (SC) route with lower neuropathy risk and no loss of anti-myeloma efficacy compared to original standard IV twice weekly schedule. Weekly SC should therefore yield the best therapeutic index and is widely used but has not been compared to established administration schedules in the context of a clinical trial. Methods Comprehensive electronic medical record review was done for disease control and neuropathy symptoms of 344 consecutive patients who received their first BTZ-containing regimen for myeloma or AL amyloidosis before or after we changed to SC weekly in December 2010. Univariate and multivariable analyses were carried out that adjusted for age, underlying disease, concurrently used anticancer agents, underlying conditions predisposing to neuropathy, and number of prior regimens compared SC weekly to other schedules. Results Fifty-three patients received BTZ SC weekly, 17 SC twice weekly, 127 IV weekly and 147 IV twice weekly. Risk for neuropathy of any grade was higher with other schedules compared to SC weekly (44.3% vs. 26.9%, p = 0.001) while response rate was similar (72.1% vs. 76.6%, respectively, p = 0.15). Multivariable analyses upheld higher neuropathy risk (Odds ratio 2.45, 95% CI 1.26–4.76, p = 0.008) while the likelihood of not achieving a response (= partial response or better) was comparable (Odds ratio 1.25, 95% CI 0.58–2.71, p = 0.56) for other schedules compared to SC weekly, respectively. Lower neuropathy risk translated into longer treatment duration when BTZ was started SC weekly (p = 0.001). Conclusions Weekly SC BTZ has activity comparable to other schedules and causes low rates of neuropathy. PMID:28278302
Skylab 3 crew during training in Orbital Workshop trainer
1973-06-19
S73-28412 (February 1973) --- The three members of the prime crew of the third of three scheduled manned Skylab missions (Skylab 4) go through Skylab preflight training in the Mission Training and Simulation Facility at the Johnson Space Center. Astronaut Gerald P. Carr (on right), Skylab 4 commander, is seated at a simulator which represents the control and display console of the Apollo Telescope Mount which is located in the space station's Multiple Docking Adapter. Seated on the left is scientist-astronaut Edward G. Gibson, Skylab 4 science pilot. In the left background is astronaut William R. Pogue, Skylab 4 pilot. (Unmanned Skylab 1 will carry the Skylab space station payload into Earth orbit). Photo credit: NASA
Differential reinforcement and resistance to change of divided-attention performance.
Podlesnik, Christopher A; Thrailkill, Eric; Shahan, Timothy A
2012-06-01
Behavioral momentum theory provides a framework for understanding how conditions of reinforcement influence instrumental response strength under conditions of disruption (i.e., resistance to change). The present experiment examined resistance to change of divided-attention performance when different overall probabilities of reinforcement were arranged across two components of a multiple schedule. Pigeons responded in a delayed-matching-to-sample procedure with compound samples (color + line orientation) and element comparisons (two colors or two line orientations). Reinforcement ratios of 1:9, 1:1, and 9:1 for accurate matches on the two types of comparison trials were examined across conditions using reinforcement probabilities (color/lines) of .9/.1, .5/.5, and .1/.9 in the rich component and .18/.02, .1/.1, and .02/.18 in the lean component. Relative accuracy with color and line comparisons was an orderly function of relative reinforcement, but this relation did not depend on the overall rate of reinforcement between components. The resistance to change of divided-attention performance was greater for both trial types in the rich component with presession feeding and extinction, but not with decreases in sample duration. These findings suggest promise for the applicability of quantitative models of operant behavior to divided-attention performance, but they highlight the need to further explore conditions impacting the resistance to change of attending.
Differential reinforcement and resistance to change of divided-attention performance
Thrailkill, Eric
2016-01-01
Behavioral momentum theory provides a framework for understanding how conditions of reinforcement influence instrumental response strength under conditions of disruption (i.e., resistance to change). The present experiment examined resistance to change of divided-attention performance when different overall probabilities of reinforcement were arranged across two components of a multiple schedule. Pigeons responded in a delayed-matching-to-sample procedure with compound samples (color + line orientation) and element comparisons (two colors or two line orientations). Reinforcement ratios of 1:9, 1:1, and 9:1 for accurate matches on the two types of comparison trials were examined across conditions using reinforcement probabilities (color/lines) of .9/.1, .5/.5, and .1/.9 in the rich component and .18/.02, .1/.1, and .02/.18 in the lean component. Relative accuracy with color and line comparisons was an orderly function of relative reinforcement, but this relation did not depend on the overall rate of reinforcement between components. The resistance to change of divided-attention performance was greater for both trial types in the rich component with presession feeding and extinction, but not with decreases in sample duration. These findings suggest promise for the applicability of quantitative models of operant behavior to divided-attention performance, but they highlight the need to further explore conditions impacting the resistance to change of attending. PMID:22038737
Kuprijanov, A; Gnoth, S; Simutis, R; Lübbert, A
2009-02-01
Design and experimental validation of advanced pO(2) controllers for fermentation processes operated in the fed-batch mode are described. In most situations, the presented controllers are able to keep the pO(2) in fermentations for recombinant protein productions exactly on the desired value. The controllers are based on the gain-scheduling approach to parameter-adaptive proportional-integral controllers. In order to cope with the most often appearing distortions, the basic gain-scheduling feedback controller was complemented with a feedforward control component. This feedforward/feedback controller significantly improved pO(2) control. By means of numerical simulations, the controller behavior was tested and its parameters were determined. Validation runs were performed with three Escherichia coli strains producing different recombinant proteins. It is finally shown that the new controller leads to significant improvements in the signal-to-noise ratio of other key process variables and, thus, to a higher process quality.
DOPAMINE POSTSYNAPTIC RECEPTOR EFFECTS OF RESTRICTED SCHEDULES OF ELECTROCONVULSIVE SHOCK
Andrade, Chittaranjan; Gangadhar, B.N.; Meena, M.; Pradhan, N.
1990-01-01
SUMMMARY Little work is available on the acute and time-dependant dopaminergic effects of single electroconvulsive shock (ECS) and multiple ECS despite the posited clinical utility of such schedules of electroconvulsive therapy (ECT) administration and the posited role of dopaminergic mechanisms in iieuropsychiatric disorders. In this study, using the apomorphine-induced motility-alteration behavioural paradigm, single session multiple ECS was found to produce no significant effect while single ECS behaviourally downregulated dopamine postsynaptic receptor functioning one week after the ECS, which effect was also seen (albeit to a lesser extent) a further week later. These findings indicate a possible application of restricted schedules of ECT to dopamine postsynaptic receptor supersensitivity syndromes. Lines for future research are suggested. PMID:21927479
Refurbishment and Automation of the Thermal/Vacuum Facilities at the Goddard Space Flight Center
NASA Technical Reports Server (NTRS)
Donohue, John T.; Johnson, Chris; Ogden, Rick; Sushon, Janet
1998-01-01
The thermal/vacuum facilities located at the Goddard Space Flight Center (GSFC) have supported both manned and unmanned space flight since the 1960s. Of the 11 facilities, currently 10 of the systems are scheduled for refurbishment and/or replacement as part of a 5-year implementation. Expected return on investment includes the reduction in test schedules, improvements in the safety of facility operations, reduction in the complexity of a test and the reduction in personnel support required for a test. Additionally, GSFC will become a global resource renowned for expertise in thermal engineering, mechanical engineering and for the automation of thermal/vacuum facilities and thermal/vacuum tests. Automation of the thermal/vacuum facilities includes the utilization of Programmable Logic Controllers (PLCs) and the use of Supervisory Control and Data Acquisition (SCADA) systems. These components allow the computer control and automation of mechanical components such as valves and pumps. In some cases, the chamber and chamber shroud require complete replacement while others require only mechanical component retrofit or replacement. The project of refurbishment and automation began in 1996 and has resulted in the computer control of one Facility (Facility #225) and the integration of electronically controlled devices and PLCs within several other facilities. Facility 225 has been successfully controlled by PLC and SCADA for over one year. Insignificant anomalies have occurred and were resolved with minimal impact to testing and operations. The amount of work remaining to be performed will occur over the next four to five years. Fiscal year 1998 includes the complete refurbishment of one facility, computer control of the thermal systems in two facilities, implementation of SCADA and PLC systems to support multiple facilities and the implementation of a Database server to allow efficient test management and data analysis.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Spanos, W.J. Jr.; Clery, M.; Perez, C.A.
1994-07-30
The purpose was to determine late complication incidence for pelvic palliation using accelerated multiple daily fraction radiation [Radiation Therapy Oncology Group (RTOG) 8502]. None of the patients with < 30 Gy (less than three courses) developed late toxicity. A total of 11/193 (6%) developed Grade 3+ late toxicity (nine Grade 3, on Grade 4, one Grade 5). Actuarial analysis of complication rate by survival time for Grades 3, 4, and 5 shows a cumulative incidence for complications after 6 months that plateaus at 6.9% by 18 months. The cumulative incidence for Grades 4 and 5 is 2.0% by 12 months.more » The difference in late effect for the 2-week rest vs. 4-week rest was not statistically different (p = .47). Patient factors evaluated for increased risk of late complications included prior surgeries, age, sex, KPS and primary. None were found to have significant statistical correlations with late effects. The crude late complications rate is 6%. Actuarial analysis using cumulative incidence shows 6.9% by 18 months. This represents a significant decrease in late complications from 49% seen with higher dose per fraction (10 Gy {times} 3) piloted by Radiation Therapy Oncology Group (7905) for a similar group of patients. Long-term analysis of late complication indicates this schedule can be used in the pelvis with relatively low incidence of complication. This schedule has significant logistic benefits and has been shown to produce good tumor regression and excellent palliation of symptoms. 14 refs., 4 figs., 4 tabs.« less
Wang, Fang; Zhang, Ming; Xie, Bing-Feng; Cao, Han; Tong, Shao-Yong; Wang, Jun-Rong; Yu, Xiao-Ping; Tang, Yang; Yang, Jing-Ran; Sun, Ming-Bo
2013-04-01
To study the effect of aluminume adjuvant and immunization schedule on immunogenicity of Sabin inactivated poliovirus vaccine. Four batches of Sabin IPV were produced by different concentrations of type 1, 2, and 3 poliovirus and administrated on three-dose schedule at 0, 1, 2 months and 0, 2, 4 months on rats. Serum samples were collected one month after each dose and neutralizing antibody titers against three types poliovirus were determined by micro-neutralization assay. The GMTs of neutralizing antibodies against three types poliovirus increased significantly and the seropositivity rates were 100% in all groups after 3 doses. There was no significant difference between two immunization schedules, and the 0, 2, 4 month schedule could induce higher level neutralizing antibody compared to the 0, 1, 2 month schedule. The groups with aluminum adjuvant could induce higher level neutralizing antibody compared to the groups without adjuvant. Aluminum djuvant and immunization schedule could improve the immunogenicity of Sabin IPV.
NASA Technical Reports Server (NTRS)
Adair, Jerry R.
1994-01-01
This paper is a consolidated report on ten major planning and scheduling systems that have been developed by the National Aeronautics and Space Administration (NASA). A description of each system, its components, and how it could be potentially used in private industry is provided in this paper. The planning and scheduling technology represented by the systems ranges from activity based scheduling employing artificial intelligence (AI) techniques to constraint based, iterative repair scheduling. The space related application domains in which the systems have been deployed vary from Space Shuttle monitoring during launch countdown to long term Hubble Space Telescope (HST) scheduling. This paper also describes any correlation that may exist between the work done on different planning and scheduling systems. Finally, this paper documents the lessons learned from the work and research performed in planning and scheduling technology and describes the areas where future work will be conducted.
Landslide: Systematic Dynamic Race Detection in Kernel Space
2012-05-01
schedule_in_flight← true; CAUSE_TIMER_INTERRUPT(); end if end function Thread Scheduling Finally, the Landslide scheduler is responsible for managing ...child process vanish() simultaneously. • double_wait: Tests interactions of multiple waiters on a single child. • double_thread_fork: Tests for...conditions using Landslide. We describe them here. • Too many waiters allowed. Using the double_wait test case, Group 1 found a bug in which more threads
2007-10-01
KENNEDY SPACE CENTER, FLA. -- In the Space Station Processing Facility at NASA's Kennedy Space Center, the starboard arm of the Special Purpose Dexterous Manipulator, known as Dextre, is lowered toward the base for installation. Dextre is a sophisticated dual-armed robot, which is part of Canada's contribution to the International Space Station (ISS). Along with Canadarm2, whose technical name is the Space Station Remote Manipulator System, and a moveable work platform called the Mobile Base System, these three elements form a robotic system called the Mobile Servicing System, or MSS. The three components have been designed to work together or independently. Dextre is part of the payload scheduled on mission STS-123, targeted to launch Feb. 14. Photo credit: NASA/George Shelton
NASA Astrophysics Data System (ADS)
Toparli, M. Burak; Fitzpatrick, Michael E.; Gungor, Salih
2015-09-01
In this study, residual stress fields, including the near-surface residual stresses, were determined for an Al7050-T7451 sample after laser peening. The contour method was applied to measure one component of the residual stress, and the relaxed stresses on the cut surfaces were then measured by X-ray diffraction. This allowed calculation of the three orthogonal stress components using the superposition principle. The near-surface results were validated with results from incremental hole drilling and conventional X-ray diffraction. The results demonstrate that multiple residual stress components can be determined using a combination of the contour method and another technique. If the measured stress components are congruent with the principal stress axes in the sample, then this allows for determination of the complete stress tensor.
Scheduling multicore workload on shared multipurpose clusters
NASA Astrophysics Data System (ADS)
Templon, J. A.; Acosta-Silva, C.; Flix Molina, J.; Forti, A. C.; Pérez-Calero Yzquierdo, A.; Starink, R.
2015-12-01
With the advent of workloads containing explicit requests for multiple cores in a single grid job, grid sites faced a new set of challenges in workload scheduling. The most common batch schedulers deployed at HEP computing sites do a poor job at multicore scheduling when using only the native capabilities of those schedulers. This paper describes how efficient multicore scheduling was achieved at the sites the authors represent, by implementing dynamically-sized multicore partitions via a minimalistic addition to the Torque/Maui batch system already in use at those sites. The paper further includes example results from use of the system in production, as well as measurements on the dependence of performance (especially the ramp-up in throughput for multicore jobs) on node size and job size.
A scalable approach to solving dense linear algebra problems on hybrid CPU-GPU systems
Song, Fengguang; Dongarra, Jack
2014-10-01
Aiming to fully exploit the computing power of all CPUs and all graphics processing units (GPUs) on hybrid CPU-GPU systems to solve dense linear algebra problems, in this paper we design a class of heterogeneous tile algorithms to maximize the degree of parallelism, to minimize the communication volume, and to accommodate the heterogeneity between CPUs and GPUs. The new heterogeneous tile algorithms are executed upon our decentralized dynamic scheduling runtime system, which schedules a task graph dynamically and transfers data between compute nodes automatically. The runtime system uses a new distributed task assignment protocol to solve data dependencies between tasksmore » without any coordination between processing units. By overlapping computation and communication through dynamic scheduling, we are able to attain scalable performance for the double-precision Cholesky factorization and QR factorization. Finally, our approach demonstrates a performance comparable to Intel MKL on shared-memory multicore systems and better performance than both vendor (e.g., Intel MKL) and open source libraries (e.g., StarPU) in the following three environments: heterogeneous clusters with GPUs, conventional clusters without GPUs, and shared-memory systems with multiple GPUs.« less
A scalable approach to solving dense linear algebra problems on hybrid CPU-GPU systems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Song, Fengguang; Dongarra, Jack
Aiming to fully exploit the computing power of all CPUs and all graphics processing units (GPUs) on hybrid CPU-GPU systems to solve dense linear algebra problems, in this paper we design a class of heterogeneous tile algorithms to maximize the degree of parallelism, to minimize the communication volume, and to accommodate the heterogeneity between CPUs and GPUs. The new heterogeneous tile algorithms are executed upon our decentralized dynamic scheduling runtime system, which schedules a task graph dynamically and transfers data between compute nodes automatically. The runtime system uses a new distributed task assignment protocol to solve data dependencies between tasksmore » without any coordination between processing units. By overlapping computation and communication through dynamic scheduling, we are able to attain scalable performance for the double-precision Cholesky factorization and QR factorization. Finally, our approach demonstrates a performance comparable to Intel MKL on shared-memory multicore systems and better performance than both vendor (e.g., Intel MKL) and open source libraries (e.g., StarPU) in the following three environments: heterogeneous clusters with GPUs, conventional clusters without GPUs, and shared-memory systems with multiple GPUs.« less
Production Scheduling for Rehabilitation Workshops.
ERIC Educational Resources Information Center
Hietala, David A.
This publication examines production scheduling procedures for sheltered workshops. The manual includes three major sections: (1) the importance and benefits of production scheduling; (2) how-to information on performing basic scheduling in the workshop; and (3) answers to the question, What makes production scheduling work? The scheduling…
Interaction Between Strategic and Local Traffic Flow Controls
NASA Technical Reports Server (NTRS)
Grabbe, Son; Sridhar, Banavar; Mukherjee, Avijit; Morando, Alexander
2010-01-01
The loosely coordinated sets of traffic flow management initiatives that are operationally implemented at the national- and local-levels have the potential to under, over, and inconsistently control flights. This study is designed to explore these interactions through fast-time simulations with an emphasis on identifying inequitable situations in which flights receive multiple uncoordinated delays. Two operationally derived scenarios were considered in which flights arriving into the Dallas/Fort Worth International Airport were first controlled at the national-level, either with a Ground Delay Program or a playbook reroute. These flights were subsequently controlled at the local level. The Traffic Management Advisor assigned them arrival scheduling delays. For the Ground Delay Program scenarios, between 51% and 53% of all arrivals experience both pre-departure delays from the Ground Delay Program and arrival scheduling delays from the Traffic Management Advisor. Of the subset of flights that received multiple delays, between 5.7% and 6.4% of the internal departures were first assigned a pre-departure delay by the Ground Delay Program, followed by a second pre-departure delay as a result of the arrival scheduling. For the playbook reroute scenario, Dallas/Fort Worth International Airport arrivals were first assigned pre-departure reroutes based on the MW_2_DALLAS playbook plan, and were subsequently assigned arrival scheduling delays by the Traffic Management Advisor. Since the airport was operating well below capacity when the playbook reroute was in effect, only 7% of the arrivals were observed to receive both rerouting and arrival scheduling delays. Findings from these initial experiments confirm field observations that Ground Delay Programs operated in conjunction with arrival scheduling can result in inequitable situations in which flights receive multiple uncoordinated delays.
Lin, Lili; Yan, Rong; Liu, Yongqiang; Jiang, Wenju
2010-11-01
The artificial biomass based on three biomass components (cellulose, hemicellulose and lignin) were developed on the basis of a simplex-lattice approach. Together with a natural biomass sample, they were employed in enzymatic hydrolysis researches. Different enzyme combines of two commercial enzymes (ACCELLERASE 1500 and OPTIMASH BG) showed a potential to hydrolyze hemicellulose completely. Negligible interactions among the three components were observed, and the used enzyme ACCELLERASE 1500 was proven to be weak lignin-binding. On this basis, a multiple linear-regression equation was established for predicting the reducing sugar yield based on the component proportions in a biomass. The hemicellulose and cellulose in a biomass sample were found to have different contributions in staged hydrolysis at different time periods. Furthermore, the hydrolysis of rice straw was conducted to validate the computation approach through considerations of alkaline solution pretreatment and combined enzymes function, so as to understand better the nature of biomass hydrolysis, from the aspect of three biomass components.
Considerations for Creating Multi-Language Personality Norms: A Three-Component Model of Error
ERIC Educational Resources Information Center
Meyer, Kevin D.; Foster, Jeff L.
2008-01-01
With the increasing globalization of human resources practices, a commensurate increase in demand has occurred for multi-language ("global") personality norms for use in selection and development efforts. The combination of data from multiple translations of a personality assessment into a single norm engenders error from multiple sources. This…
Quasi-reinforcement: control of responding by a percentage-reinforcement schedule1
Neuringer, Allen J.; Chung, Shin-Ho
1967-01-01
When a variable-interval schedule of reinforcement was segmented into small fixed-interval components, with reinforcements following some components and brief blackouts following the others, rate of responding doubled and a positively accelerated pattern within each component was obtained. Presented according to this percentage reinforcement paradigm, the blackouts approximated the functions of a food reinforcer. These effects occurred only when the behavior sequence required to produce reinforcement was identical to that required to produce blackout. The quasi-reinforcing effects of these blackout stimuli suggest that a neutral stimulus need not occasion or accompany a primary reinforcer to acquire reinforcing properties. PMID:16811304
Shaikh, Alfiya; Nayak, Priyanka; Navada, Rajesh
2017-01-01
Introduction Globalization and urbanization have resulted in an increased demand on sand dredging. Legal and environmental restrictions on automated dredging have led to a rise in manual technique. The working techniques and environment involved in manual sand dredging may expose the workers to multiple work related disorders. Aim To determine the health risks and occupational hazards involved in manual sand dredging. Materials and Methods An assessment schedule was developed and content was validated by five experts for the study. A cross-sectional study was then conducted using this assessment schedule. Thirty manual sand dredgers were recruited from three randomly selected docks on Swarna riverbed in Udupi district, Karnataka, India. A detailed work and worksite assessments were conducted using systematic observation and close-ended questions. Work-related health risk evaluation included onsite-evaluation and self-reported health complains. Results The prevalence of musculoskeletal pain and discomfort was 93.34% with lower back (70%), shoulder (56.7%) and neck (46.7%) involvements being most common regions. Prevalence of sensory deficits at multiple site and ear pain was 66.6% and 76.6% respectively. All the workers recruited, complained of dermatological and ophthalmic involvements. Also, lack of health and safety measures like personal protective devices and security schemes were identified. Conclusion This study shows a high prevalence of multiple work-related disorders and hazards involved in manual sand dredging, a highly demanding job in coastal Karnataka. Lack of health and safety measures were also identified. PMID:28892936
Balancing Authority Cooperation Concepts - Intra-Hour Scheduling
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hunsaker, Matthew; Samaan, Nader; Milligan, Michael
2013-03-29
The overall objective of this study was to understand, on an Interconnection-wide basis, the effects intra-hour scheduling compared to hourly scheduling. Moreover, the study sought to understand how the benefits of intra-hour scheduling would change by altering the input assumptions in different scenarios. This report describes results of three separate scenarios with differing key assumptions and comparing the production costs between hourly scheduling and 10-minute scheduling performance. The different scenarios were chosen to provide insight into how the estimated benefits might change by altering input assumptions. Several key assumptions were different in the three scenarios, however most assumptions were similarmore » and/or unchanged among the scenarios.« less
ERIC Educational Resources Information Center
Goetz, Lori; O'Farrell, Nora
1999-01-01
This article describes a three-component package to facilitate social supports for students who are deaf-blind in general education classes. The components are: ongoing provision of information, provision of interactive, multiple communication media, and facilitation of social interactions. Case studies of four students with deaf-blindness…
A real-time architecture for time-aware agents.
Prouskas, Konstantinos-Vassileios; Pitt, Jeremy V
2004-06-01
This paper describes the specification and implementation of a new three-layer time-aware agent architecture. This architecture is designed for applications and environments where societies of humans and agents play equally active roles, but interact and operate in completely different time frames. The architecture consists of three layers: the April real-time run-time (ART) layer, the time aware layer (TAL), and the application agents layer (AAL). The ART layer forms the underlying real-time agent platform. An original online, real-time, dynamic priority-based scheduling algorithm is described for scheduling the computation time of agent processes, and it is shown that the algorithm's O(n) complexity and scalable performance are sufficient for application in real-time domains. The TAL layer forms an abstraction layer through which human and agent interactions are temporally unified, that is, handled in a common way irrespective of their temporal representation and scale. A novel O(n2) interaction scheduling algorithm is described for predicting and guaranteeing interactions' initiation and completion times. The time-aware predicting component of a workflow management system is also presented as an instance of the AAL layer. The described time-aware architecture addresses two key challenges in enabling agents to be effectively configured and applied in environments where humans and agents play equally active roles. It provides flexibility and adaptability in its real-time mechanisms while placing them under direct agent control, and it temporally unifies human and agent interactions.
Demand side management in recycling and electricity retail pricing
NASA Astrophysics Data System (ADS)
Kazan, Osman
This dissertation addresses several problems from the recycling industry and electricity retail market. The first paper addresses a real-life scheduling problem faced by a national industrial recycling company. Based on their practices, a scheduling problem is defined, modeled, analyzed, and a solution is approximated efficiently. The recommended application is tested on the real-life data and randomly generated data. The scheduling improvements and the financial benefits are presented. The second problem is from electricity retail market. There are well-known patterns in daily usage in hours. These patterns change in shape and magnitude by seasons and days of the week. Generation costs are multiple times higher during the peak hours of the day. Yet most consumers purchase electricity at flat rates. This work explores analytic pricing tools to reduce peak load electricity demand for retailers. For that purpose, a nonlinear model that determines optimal hourly prices is established based on two major components: unit generation costs and consumers' utility. Both are analyzed and estimated empirically in the third paper. A pricing model is introduced to maximize the electric retailer's profit. As a result, a closed-form expression for the optimal price vector is obtained. Possible scenarios are evaluated for consumers' utility distribution. For the general case, we provide a numerical solution methodology to obtain the optimal pricing scheme. The models recommended are tested under various scenarios that consider consumer segmentation and multiple pricing policies. The recommended model reduces the peak load significantly in most cases. Several utility companies offer hourly pricing to their customers. They determine prices using historical data of unit electricity cost over time. In this dissertation we develop a nonlinear model that determines optimal hourly prices with parameter estimation. The last paper includes a regression analysis of the unit generation cost function obtained from Independent Service Operators. A consumer experiment is established to replicate the peak load behavior. As a result, consumers' utility function is estimated and optimal retail electricity prices are computed.
Steel for Bodies: Ammunition Readiness During the Korean War
2003-01-01
Committee, contradicted Secretary of Defense Robert Lovett by stating that serious bottlenecks still existed and that deliveries were well behind schedule ...disagreement over whether there had in fact been shortages, Chairman Saltonstall scheduled a hearing on 10 March 1953, at which both Army Chief of...packaging for shipment were contracted out to manufacturers. The planning and coordination to schedule components to be completed, on hand, and ready for
Protocol, Engineering Research Center, University of California, Santa Barbara
2005-12-01
minimizing the energy consumption in idle periods. We have designed an asynchronous wakeup schedule based on the theory of block designs. The idea is...performance of ad hoc networks through innovative packet scheduling (Baker). "* Developed a number of novel schemes to ensure loop freedom in on demand routing...network nodes to schedule their transmissions to avoid collisions (Garcia-Luna-Aceves). "* Designed and analyzed the Hybrid Activation Multiple Access (HAMA
2012-09-01
scheduler to adapt its uplink and downlink assignments to channel conditions. Sleep mode is used by the MS to minimize power drain and radio...is addressed in one resource unit, while for multi-user (MU) schemes , multiple users can be scheduled in one resource unit. Open-loop techniques...17 7. Mobility and Power Management ......................................... 18 8. Scheduling Services
Benchmarking surgeon satisfaction at academic health centers: a nationwide comparative survey.
Drachman, D A
1996-01-01
Forty-six academic health centers (AHCs) belonging to the University HealthSystem consortium joined forces to compare the efficiency of their surgical services and to identify best practices. In addition to measures of operational performance, surgeon satisfaction with the surgical services provided was measured by using a standardized questionnaire. From hospital records, indicators of the efficiency of surgical services were collected in three main areas: scheduling, preoperative testing and assessment, and the intraoperative process. Responding to a mail questionnaire, a sample of surgeons rated their satisfaction with key aspects of surgical services including scheduling, operating room staff, and equipment/supplies. On the basis of a review of the operational measures and the survey results, high performers were identified. Site visits were made to several of these high performers to uncover the critical factors responsible for their success. The survey revealed distinct variations in surgeon satisfaction across the participating institutions. Numerical benchmarks were obtained for surgeon satisfaction with each key component of surgical services. Scheduling was the most important component of overall surgeon satisfaction, explaining 71% of the variance in the rating of overall satisfaction with surgical services. High operational efficiency and high surgeon satisfaction were not incompatible. Several of the participating institutions were able to achieve both. These results were disseminated to all of the participants at a national meeting as well as in written form. The surgeon satisfaction survey allowed the participants to establish benchmarks for surgeon satisfaction for each key component of the surgical services they receive. The site visits revealed several common characteristics of highly efficient surgical services. Taken by themselves, the participating institutions might have been reluctant to consider adopting these best practices for fear of alienating the surgical staff. The availability of data on surgeon satisfaction showed the participants that these best practices can coexist with high levels of surgeon satisfaction. This has helped to promote their adoption by the other participating institutions.
Bankefors, Johan; Nord, Lars I; Kenne, Lennart
2010-02-01
A method for separation and detection of major and minor components in complex mixtures has been developed, utilising two-dimensional high-performance liquid chromatography (2D-HPLC) combined with electrospray ionisation ion-trap multiple-stage mass spectrometry (ESI-ITMS(n)). Chromatographic conditions were matched with mass spectrometric detection to maximise the number of components that could be separated. The described procedure has proven useful to discern several hundreds of saponin components when applied to Quillaja saponaria Molina bark extracts. The discrimination of each saponin component relies on the fact that three coordinates (x, y, z) for each component can be derived from the retention time of the two chromatographic steps (x, y) and the m/z-values from the multiple-stage mass spectrometry (z(n), n=1, 2, ...). Thus an improved graphical representation was obtained by combining retention times from the two-stage separation with +MS(1) (z(1)) and the additional structural information from the second mass stage +MS(2) (z(2), z(3)) corresponding to the main fragment ions. By this approach three-dimensional plots can be made that reveal both the chromatographic and structural properties of a specific mixture which can be useful in fingerprinting of complex mixtures. 2009 Elsevier B.V. All rights reserved.
An evaluation of resistance to change with unconditioned and conditioned reinforcers.
Vargo, Kristina K; Ringdahl, Joel E
2015-09-01
Several reinforcer-related variables influence a response's resistance to change (Nevin, 1974). Reinforcer type (i.e., conditioned or unconditioned) is a reinforcer-related variable that has not been studied with humans but may have clinical implications. In Experiment 1, we identified unconditioned and conditioned reinforcers of equal preference. In Experiments 2, 3, and 4, we reinforced participants' behavior during a baseline phase using a multiple variable-interval (VI) 30-s VI 30-s schedule with either conditioned (i.e., token) or unconditioned (i.e., food; one type of reinforcement in each component) reinforcement. After equal reinforcement rates across components, we introduced a disruptor. Results of Experiments 2 and 3 showed that behaviors were more resistant to extinction and distraction, respectively, with conditioned than with unconditioned reinforcers. Results of Experiment 4, however, showed that when prefeeding disrupted responding, behaviors were more resistant to change with unconditioned reinforcers than with conditioned reinforcers. © Society for the Experimental Analysis of Behavior.
Riesen, Eleanor; Morley, Michelle; Clendinneng, Debra; Ogilvie, Susan; Ann Murray, Mary
2012-07-01
Interprofessional simulation interventions, especially when face-to-face, involve considerable resources and require that all participants convene in a single location at a specific time. Scheduling multiple people across different programs is an important barrier to implementing interprofessional education interventions. This study explored a novel way to overcome the challenges associated with scheduling interprofessional learning experiences through the use of simulations in a virtual environment (Web.Alive™) where learners interact as avatars. In this study, 60 recent graduates from nursing, paramedic, police, and child and youth service programs participated in a 2-day workshop designed to improve interprofessional competencies through a blend of learning environments that included virtual face-to-face experiences, traditional face-to-face experiences and online experiences. Changes in learners' interprofessional competence were assessed through three outcomes: change in interprofessional attitudes pre- to post-workshop, self-perceived changes in interprofessional competence and observer ratings of performance across three clinical simulations. Results from the study indicate that from baseline to post-intervention, there was significant improvement in learners' interprofessional competence across all outcomes, and that the blended learning environment provided an acceptable way to develop these competencies.
Scheduling lessons learned from the Autonomous Power System
NASA Technical Reports Server (NTRS)
Ringer, Mark J.
1992-01-01
The Autonomous Power System (APS) project at NASA LeRC is designed to demonstrate the applications of integrated intelligent diagnosis, control, and scheduling techniques to space power distribution systems. The project consists of three elements: the Autonomous Power Expert System (APEX) for Fault Diagnosis, Isolation, and Recovery (FDIR); the Autonomous Intelligent Power Scheduler (AIPS) to efficiently assign activities start times and resources; and power hardware (Brassboard) to emulate a space-based power system. The AIPS scheduler was tested within the APS system. This scheduler is able to efficiently assign available power to the requesting activities and share this information with other software agents within the APS system in order to implement the generated schedule. The AIPS scheduler is also able to cooperatively recover from fault situations by rescheduling the affected loads on the Brassboard in conjunction with the APEX FDIR system. AIPS served as a learning tool and an initial scheduling testbed for the integration of FDIR and automated scheduling systems. Many lessons were learned from the AIPS scheduler and are now being integrated into a new scheduler called SCRAP (Scheduler for Continuous Resource Allocation and Planning). This paper will service three purposes: an overview of the AIPS implementation, lessons learned from the AIPS scheduler, and a brief section on how these lessons are being applied to the new SCRAP scheduler.
Learning to improve iterative repair scheduling
NASA Technical Reports Server (NTRS)
Zweben, Monte; Davis, Eugene
1992-01-01
This paper presents a general learning method for dynamically selecting between repair heuristics in an iterative repair scheduling system. The system employs a version of explanation-based learning called Plausible Explanation-Based Learning (PEBL) that uses multiple examples to confirm conjectured explanations. The basic approach is to conjecture contradictions between a heuristic and statistics that measure the quality of the heuristic. When these contradictions are confirmed, a different heuristic is selected. To motivate the utility of this approach we present an empirical evaluation of the performance of a scheduling system with respect to two different repair strategies. We show that the scheduler that learns to choose between the heuristics outperforms the same scheduler with any one of two heuristics alone.
Yoo, Woo-Jin; Nguyen, Thanh V Q; Kobayashi, Shū
2014-09-15
A copper-catalyzed multicomponent coupling reaction between in situ generated ortho-arynes, terminal alkynes, and carbon dioxide was developed to access isocoumarins in moderate to good yields. The key to this CO2-incorporating reaction was the use of a versatile N-heterocyclic carbene/copper complex that was able to catalyze multiple transformations within the three-component reaction. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
How, Jonathan; Minden, Mark D.; Brian, Leber; Chen, Eric X.; Brandwein, Joseph; Schuh, Andre C.; Schimmer, Aaron D.; Gupta, Vikas; Webster, Sheila; Degelder, Tammy; Haines, Patricia; Stayner, Lee-Anne; McGill, Shauna; Wang, Lisa; Piekarz, Richard; Wong, Tracy; Siu, Lillian L.; Espinoza-Delgado, Igor; Holleran, Julianne L.; Egorin, Merrill J.; Yee, Karen W. L.
2015-01-01
This phase I trial evaluated two schedules of escalating vorinostat in combination with decitabine every 28 days: (i) sequential or (ii) concurrent. There were three dose-limiting toxicities: grade 3 fatigue and generalized muscle weakness on the sequential schedule (n = 1) and grade 3 fatigue on the concurrent schedule (n = 2). The maximum tolerated dose was not reached on both planned schedules. The overall response rate (ORR) was 23% (three complete response [CR], two CR with incomplete incomplete blood count recovery [CRi], one partial response [PR] and two morphological leukemic free state [MLFS]). The ORR for all and previously untreated patients in the sequential arm was 13% (one CRi; one MLFS) and 0% compared to 30% (three CR; one CRi; one PR; one MLFS) and 36% in the concurrent arm (p = 0.26 for both), respectively. Decitabine plus vorinostat was safe and has clinical activity in patients with previously untreated acute myeloid leukemia. Responses appear higher with the concurrent dose schedule. Cumulative toxicities may limit long-term usage on the current dose/schedules. PMID:25682963
Aaboud, M.; Aad, G.; Abbott, B.; ...
2017-06-28
Two-particle pseudorapidity correlations are measured in √ sNN = 2.76TeV Pb + Pb, √ sNN = 5.02TeV p + Pb, and √s = 13 TeV pp collisions at the Large Hadron Collider (LHC), with total integrated luminosities of approximately 7μb –1, 28 nb –1, and 65 nb –1, respectively. The correlation function C N(η 1,η 2) is measured as a function of event multiplicity using charged particles in the pseudorapidity range |η| < 2.4. The correlation function contains a significant short-range component, which is estimated and subtracted. After removal of the short-range component, the shape of the correlation function ismore » described approximately by 1 + < a2 1 > 1/2η 1η 2 in all collision systems over the full multiplicity range. The values of < a 2 1 > 1/2 are consistent for the opposite-charge pairs and same-charge pairs, and for the three collision systems at similar multiplicity. The values of < a 2 1 > 1/2 and the magnitude of the short-range component both follow a power-law dependence on the event multiplicity. Here, the short-range component in p + Pb collisions, after symmetrizing the proton and lead directions, is found to be smaller at a given η than in pp collisions with comparable multiplicity.« less
NASA Astrophysics Data System (ADS)
Aaboud, M.; Aad, G.; Abbott, B.; Abdallah, J.; Abdinov, O.; Abeloos, B.; Aben, R.; Abouzeid, O. S.; Abraham, N. L.; Abramowicz, H.; Abreu, H.; Abreu, R.; Abulaiti, Y.; Acharya, B. S.; Adamczyk, L.; Adams, D. L.; Adelman, J.; Adomeit, S.; Adye, T.; Affolder, A. A.; Agatonovic-Jovin, T.; Agricola, J.; Aguilar-Saavedra, J. A.; Ahlen, S. P.; Ahmadov, F.; Aielli, G.; Akerstedt, H.; Åkesson, T. P. A.; Akimov, A. V.; Alberghi, G. L.; Albert, J.; Albrand, S.; Alconada Verzini, M. J.; Aleksa, M.; Aleksandrov, I. N.; Alexa, C.; Alexander, G.; Alexopoulos, T.; Alhroob, M.; Ali, B.; Aliev, M.; Alimonti, G.; Alison, J.; Alkire, S. P.; Allbrooke, B. M. M.; Allen, B. W.; Allport, P. P.; Aloisio, A.; Alonso, A.; Alonso, F.; Alpigiani, C.; Alstaty, M.; Alvarez Gonzalez, B.; Álvarez Piqueras, D.; Alviggi, M. G.; Amadio, B. T.; Amako, K.; Amaral Coutinho, Y.; Amelung, C.; Amidei, D.; Amor Dos Santos, S. P.; Amorim, A.; Amoroso, S.; Amundsen, G.; Anastopoulos, C.; Ancu, L. S.; Andari, N.; Andeen, T.; Anders, C. F.; Anders, G.; Anders, J. K.; Anderson, K. J.; Andreazza, A.; Andrei, V.; Angelidakis, S.; Angelozzi, I.; Anger, P.; Angerami, A.; Anghinolfi, F.; Anisenkov, A. V.; Anjos, N.; Annovi, A.; Antel, C.; Antonelli, M.; Antonov, A.; Anulli, F.; Aoki, M.; Aperio Bella, L.; Arabidze, G.; Arai, Y.; Araque, J. P.; Arce, A. T. H.; Arduh, F. A.; Arguin, J.-F.; Argyropoulos, S.; Arik, M.; Armbruster, A. J.; Armitage, L. J.; Arnaez, O.; Arnold, H.; Arratia, M.; Arslan, O.; Artamonov, A.; Artoni, G.; Artz, S.; Asai, S.; Asbah, N.; Ashkenazi, A.; Åsman, B.; Asquith, L.; Assamagan, K.; Astalos, R.; Atkinson, M.; Atlay, N. B.; Augsten, K.; Avolio, G.; Axen, B.; Ayoub, M. K.; Azuelos, G.; Baak, M. A.; Baas, A. E.; Baca, M. J.; Bachacou, H.; Bachas, K.; Backes, M.; Backhaus, M.; Bagiacchi, P.; Bagnaia, P.; Bai, Y.; Baines, J. T.; Baker, O. K.; Baldin, E. M.; Balek, P.; Balestri, T.; Balli, F.; Balunas, W. K.; Banas, E.; Banerjee, Sw.; Bannoura, A. A. E.; Barak, L.; Barberio, E. L.; Barberis, D.; Barbero, M.; Barillari, T.; Barisits, M.-S.; Barklow, T.; Barlow, N.; Barnes, S. L.; Barnett, B. M.; Barnett, R. M.; Barnovska, Z.; Baroncelli, A.; Barone, G.; Barr, A. J.; Barranco Navarro, L.; Barreiro, F.; Barreiro Guimarães da Costa, J.; Bartoldus, R.; Barton, A. E.; Bartos, P.; Basalaev, A.; Bassalat, A.; Bates, R. L.; Batista, S. J.; Batley, J. R.; Battaglia, M.; Bauce, M.; Bauer, F.; Bawa, H. S.; Beacham, J. B.; Beattie, M. D.; Beau, T.; Beauchemin, P. H.; Bechtle, P.; Beck, H. P.; Becker, K.; Becker, M.; Beckingham, M.; Becot, C.; Beddall, A. J.; Beddall, A.; Bednyakov, V. A.; Bedognetti, M.; Bee, C. P.; Beemster, L. J.; Beermann, T. A.; Begel, M.; Behr, J. K.; Belanger-Champagne, C.; Bell, A. S.; Bella, G.; Bellagamba, L.; Bellerive, A.; Bellomo, M.; Belotskiy, K.; Beltramello, O.; Belyaev, N. L.; Benary, O.; Benchekroun, D.; Bender, M.; Bendtz, K.; Benekos, N.; Benhammou, Y.; Benhar Noccioli, E.; Benitez, J.; Benjamin, D. P.; Bensinger, J. R.; Bentvelsen, S.; Beresford, L.; Beretta, M.; Berge, D.; Bergeaas Kuutmann, E.; Berger, N.; Beringer, J.; Berlendis, S.; Bernard, N. R.; Bernius, C.; Bernlochner, F. U.; Berry, T.; Berta, P.; Bertella, C.; Bertoli, G.; Bertolucci, F.; Bertram, I. A.; Bertsche, C.; Bertsche, D.; Besjes, G. J.; Bessidskaia Bylund, O.; Bessner, M.; Besson, N.; Betancourt, C.; Bethani, A.; Bethke, S.; Bevan, A. J.; Bianchi, R. M.; Bianchini, L.; Bianco, M.; Biebel, O.; Biedermann, D.; Bielski, R.; Biesuz, N. V.; Biglietti, M.; Bilbao de Mendizabal, J.; Billoud, T. R. V.; Bilokon, H.; Bindi, M.; Binet, S.; Bingul, A.; Bini, C.; Biondi, S.; Bisanz, T.; Bjergaard, D. M.; Black, C. W.; Black, J. E.; Black, K. M.; Blackburn, D.; Blair, R. E.; Blanchard, J.-B.; Blazek, T.; Bloch, I.; Blocker, C.; Blum, W.; Blumenschein, U.; Blunier, S.; Bobbink, G. J.; Bobrovnikov, V. S.; Bocchetta, S. S.; Bocci, A.; Bock, C.; Boehler, M.; Boerner, D.; Bogaerts, J. A.; Bogavac, D.; Bogdanchikov, A. G.; Bohm, C.; Boisvert, V.; Bokan, P.; Bold, T.; Boldyrev, A. S.; Bomben, M.; Bona, M.; Boonekamp, M.; Borisov, A.; Borissov, G.; Bortfeldt, J.; Bortoletto, D.; Bortolotto, V.; Bos, K.; Boscherini, D.; Bosman, M.; Bossio Sola, J. D.; Boudreau, J.; Bouffard, J.; Bouhova-Thacker, E. V.; Boumediene, D.; Bourdarios, C.; Boutle, S. K.; Boveia, A.; Boyd, J.; Boyko, I. R.; Bracinik, J.; Brandt, A.; Brandt, G.; Brandt, O.; Bratzler, U.; Brau, B.; Brau, J. E.; Braun, H. M.; Breaden Madden, W. D.; Brendlinger, K.; Brennan, A. J.; Brenner, L.; Brenner, R.; Bressler, S.; Bristow, T. M.; Britton, D.; Britzger, D.; Brochu, F. M.; Brock, I.; Brock, R.; Brooijmans, G.; Brooks, T.; Brooks, W. K.; Brosamer, J.; Brost, E.; Broughton, J. H.; Bruckman de Renstrom, P. A.; Bruncko, D.; Bruneliere, R.; Bruni, A.; Bruni, G.; Bruni, L. S.; Brunt, Bh; Bruschi, M.; Bruscino, N.; Bryant, P.; Bryngemark, L.; Buanes, T.; Buat, Q.; Buchholz, P.; Buckley, A. G.; Budagov, I. A.; Buehrer, F.; Bugge, M. 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R.; Suzuki, S.; Svatos, M.; Swiatlowski, M.; Sykora, I.; Sykora, T.; Ta, D.; Taccini, C.; Tackmann, K.; Taenzer, J.; Taffard, A.; Tafirout, R.; Taiblum, N.; Takai, H.; Takashima, R.; Takeshita, T.; Takubo, Y.; Talby, M.; Talyshev, A. A.; Tan, K. G.; Tanaka, J.; Tanaka, M.; Tanaka, R.; Tanaka, S.; Tannenwald, B. B.; Tapia Araya, S.; Tapprogge, S.; Tarem, S.; Tartarelli, G. F.; Tas, P.; Tasevsky, M.; Tashiro, T.; Tassi, E.; Tavares Delgado, A.; Tayalati, Y.; Taylor, A. C.; Taylor, G. N.; Taylor, P. T. E.; Taylor, W.; Teischinger, F. A.; Teixeira-Dias, P.; Temming, K. K.; Temple, D.; Ten Kate, H.; Teng, P. K.; Teoh, J. J.; Tepel, F.; Terada, S.; Terashi, K.; Terron, J.; Terzo, S.; Testa, M.; Teuscher, R. J.; Theveneaux-Pelzer, T.; Thomas, J. P.; Thomas-Wilsker, J.; Thompson, E. N.; Thompson, P. D.; Thompson, A. S.; Thomsen, L. A.; Thomson, E.; Thomson, M.; Tibbetts, M. J.; Ticse Torres, R. E.; Tikhomirov, V. O.; Tikhonov, Yu. A.; Timoshenko, S.; Tipton, P.; Tisserant, S.; Todome, K.; Todorov, T.; Todorova-Nova, S.; Tojo, J.; Tokár, S.; Tokushuku, K.; Tolley, E.; Tomlinson, L.; Tomoto, M.; Tompkins, L.; Toms, K.; Tong, B.; Torrence, E.; Torres, H.; Torró Pastor, E.; Toth, J.; Touchard, F.; Tovey, D. R.; Trefzger, T.; Tricoli, A.; Trigger, I. M.; Trincaz-Duvoid, S.; Tripiana, M. F.; Trischuk, W.; Trocmé, B.; Trofymov, A.; Troncon, C.; Trottier-McDonald, M.; Trovatelli, M.; Truong, L.; Trzebinski, M.; Trzupek, A.; Tseng, J. C.-L.; Tsiareshka, P. V.; Tsipolitis, G.; Tsirintanis, N.; Tsiskaridze, S.; Tsiskaridze, V.; Tskhadadze, E. G.; Tsui, K. M.; Tsukerman, I. I.; Tsulaia, V.; Tsuno, S.; Tsybychev, D.; Tu, Y.; Tudorache, A.; Tudorache, V.; Tuna, A. N.; Tupputi, S. A.; Turchikhin, S.; Turecek, D.; Turgeman, D.; Turra, R.; Turvey, A. J.; Tuts, P. M.; Tyndel, M.; Ucchielli, G.; Ueda, I.; Ughetto, M.; Ukegawa, F.; Unal, G.; Undrus, A.; Unel, G.; Ungaro, F. C.; Unno, Y.; Unverdorben, C.; Urban, J.; Urquijo, P.; Urrejola, P.; Usai, G.; Usanova, A.; Vacavant, L.; Vacek, V.; Vachon, B.; Valderanis, C.; Valdes Santurio, E.; Valencic, N.; Valentinetti, S.; Valero, A.; Valery, L.; Valkar, S.; Valls Ferrer, J. A.; van den Wollenberg, W.; van der Deijl, P. C.; van der Graaf, H.; van Eldik, N.; van Gemmeren, P.; van Nieuwkoop, J.; van Vulpen, I.; van Woerden, M. C.; Vanadia, M.; Vandelli, W.; Vanguri, R.; Vaniachine, A.; Vankov, P.; Vardanyan, G.; Vari, R.; Varnes, E. W.; Varol, T.; Varouchas, D.; Vartapetian, A.; Varvell, K. E.; Vasquez, J. G.; Vazeille, F.; Vazquez Schroeder, T.; Veatch, J.; Veeraraghavan, V.; Veloce, L. M.; Veloso, F.; Veneziano, S.; Ventura, A.; Venturi, M.; Venturi, N.; Venturini, A.; Vercesi, V.; Verducci, M.; Verkerke, W.; Vermeulen, J. C.; Vest, A.; Vetterli, M. C.; Viazlo, O.; Vichou, I.; Vickey, T.; Vickey Boeriu, O. E.; Viehhauser, G. H. A.; Viel, S.; Vigani, L.; Villa, M.; Villaplana Perez, M.; Vilucchi, E.; Vincter, M. G.; Vinogradov, V. B.; Vittori, C.; Vivarelli, I.; Vlachos, S.; Vlasak, M.; Vogel, M.; Vokac, P.; Volpi, G.; Volpi, M.; von der Schmitt, H.; von Toerne, E.; Vorobel, V.; Vorobev, K.; Vos, M.; Voss, R.; Vossebeld, J. H.; Vranjes, N.; Vranjes Milosavljevic, M.; Vrba, V.; Vreeswijk, M.; Vuillermet, R.; Vukotic, I.; Vykydal, Z.; Wagner, P.; Wagner, W.; Wahlberg, H.; Wahrmund, S.; Wakabayashi, J.; Walder, J.; Walker, R.; Walkowiak, W.; Wallangen, V.; Wang, C.; Wang, C.; Wang, F.; Wang, H.; Wang, H.; Wang, J.; Wang, J.; Wang, K.; Wang, R.; Wang, S. M.; Wang, T.; Wang, T.; Wang, W.; Wang, X.; Wanotayaroj, C.; Warburton, A.; Ward, C. P.; Wardrope, D. R.; Washbrook, A.; Watkins, P. M.; Watson, A. T.; Watson, M. F.; Watts, G.; Watts, S.; Waugh, B. M.; Webb, S.; Weber, M. S.; Weber, S. W.; Webster, J. S.; Weidberg, A. R.; Weinert, B.; Weingarten, J.; Weiser, C.; Weits, H.; Wells, P. S.; Wenaus, T.; Wengler, T.; Wenig, S.; Wermes, N.; Werner, M.; Werner, M. D.; Werner, P.; Wessels, M.; Wetter, J.; Whalen, K.; Whallon, N. L.; Wharton, A. M.; White, A.; White, M. J.; White, R.; Whiteson, D.; Wickens, F. J.; Wiedenmann, W.; Wielers, M.; Wienemann, P.; Wiglesworth, C.; Wiik-Fuchs, L. A. M.; Wildauer, A.; Wilk, F.; Wilkens, H. G.; Williams, H. H.; Williams, S.; Willis, C.; Willocq, S.; Wilson, J. A.; Wingerter-Seez, I.; Winklmeier, F.; Winston, O. J.; Winter, B. T.; Wittgen, M.; Wittkowski, J.; Wolf, T. M. H.; Wolter, M. W.; Wolters, H.; Worm, S. D.; Wosiek, B. K.; Wotschack, J.; Woudstra, M. J.; Wozniak, K. W.; Wu, M.; Wu, M.; Wu, S. L.; Wu, X.; Wu, Y.; Wyatt, T. R.; Wynne, B. M.; Xella, S.; Xu, D.; Xu, L.; Yabsley, B.; Yacoob, S.; Yamaguchi, D.; Yamaguchi, Y.; Yamamoto, A.; Yamamoto, S.; Yamanaka, T.; Yamauchi, K.; Yamazaki, Y.; Yan, Z.; Yang, H.; Yang, H.; Yang, Y.; Yang, Z.; Yao, W.-M.; Yap, Y. C.; Yasu, Y.; Yatsenko, E.; Yau Wong, K. H.; Ye, J.; Ye, S.; Yeletskikh, I.; Yen, A. L.; Yildirim, E.; Yorita, K.; Yoshida, R.; Yoshihara, K.; Young, C.; Young, C. J. S.; Youssef, S.; Yu, D. R.; Yu, J.; Yu, J. M.; Yu, J.; Yuan, L.; Yuen, S. P. Y.; Yusuff, I.; Zabinski, B.; Zaidan, R.; Zaitsev, A. M.; Zakharchuk, N.; Zalieckas, J.; Zaman, A.; Zambito, S.; Zanello, L.; Zanzi, D.; Zeitnitz, C.; Zeman, M.; Zemla, A.; Zeng, J. C.; Zeng, Q.; Zengel, K.; Zenin, O.; Ženiš, T.; Zerwas, D.; Zhang, D.; Zhang, F.; Zhang, G.; Zhang, H.; Zhang, J.; Zhang, L.; Zhang, R.; Zhang, R.; Zhang, X.; Zhang, Z.; Zhao, X.; Zhao, Y.; Zhao, Z.; Zhemchugov, A.; Zhong, J.; Zhou, B.; Zhou, C.; Zhou, L.; Zhou, L.; Zhou, M.; Zhou, N.; Zhu, C. G.; Zhu, H.; Zhu, J.; Zhu, Y.; Zhuang, X.; Zhukov, K.; Zibell, A.; Zieminska, D.; Zimine, N. I.; Zimmermann, C.; Zimmermann, S.; Zinonos, Z.; Zinser, M.; Ziolkowski, M.; Živković, L.; Zobernig, G.; Zoccoli, A.; Zur Nedden, M.; Zwalinski, L.; Atlas Collaboration
2017-06-01
Two-particle pseudorapidity correlations are measured in √{sNN}=2.76 TeV Pb +Pb , √{sNN}=5.02 TeV p +Pb, and √{s }=13 TeV p p collisions at the Large Hadron Collider (LHC), with total integrated luminosities of approximately 7 μ b-1 , 28 nb-1, and 65 nb-1, respectively. The correlation function CN(η1,η2) is measured as a function of event multiplicity using charged particles in the pseudorapidity range |η |<2.4 . The correlation function contains a significant short-range component, which is estimated and subtracted. After removal of the short-range component, the shape of the correlation function is described approximately by 1 +
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-16
... Change To Amend OCC's Schedule of Fees to Eliminate Fees for Certain Educational Brochures July 10, 2012... change would amend OCC's Schedule of Fees to eliminate fees for three brochures to reflect that these... OCC's Schedule of Fees to eliminate fees for three brochures to reflect that these brochures are now...
Token Economy: A Systematic Review of Procedural Descriptions.
Ivy, Jonathan W; Meindl, James N; Overley, Eric; Robson, Kristen M
2017-09-01
The token economy is a well-established and widely used behavioral intervention. A token economy is comprised of six procedural components: the target response(s), a token that functions as a conditioned reinforcer, backup reinforcers, and three interconnected schedules of reinforcement. Despite decades of applied research, the extent to which the procedures of a token economy are described in complete and replicable detail has not been evaluated. Given the inherent complexity of a token economy, an analysis of the procedural descriptions may benefit future token economy research and practice. Articles published between 2000 and 2015 that included implementation of a token economy within an applied setting were identified and reviewed with a focus on evaluating the thoroughness of procedural descriptions. The results show that token economy components are regularly omitted or described in vague terms. Of the articles included in this analysis, only 19% (18 of 96 articles reviewed) included replicable and complete descriptions of all primary components. Missing or vague component descriptions could negatively affect future research or applied practice. Recommendations are provided to improve component descriptions.
Influence of Temporal Context on Value in the Multiple-Chains and Successive-Encounters Procedures
ERIC Educational Resources Information Center
O'Daly, Matthew; Angulo, Samuel; Gipson, Cassandra; Fantino, Edmund
2006-01-01
This set of studies explored the influence of temporal context across multiple-chain and multiple-successive-encounters procedures. Following training with different temporal contexts, the value of stimuli sharing similar reinforcement schedules was assessed by presenting these stimuli in concurrent probes. The results for the multiple-chain…
Departure Queue Prediction for Strategic and Tactical Surface Scheduler Integration
NASA Technical Reports Server (NTRS)
Zelinski, Shannon; Windhorst, Robert
2016-01-01
A departure metering concept to be demonstrated at Charlotte Douglas International Airport (CLT) will integrate strategic and tactical surface scheduling components to enable the respective collaborative decision making and improved efficiency benefits these two methods of scheduling provide. This study analyzes the effect of tactical scheduling on strategic scheduler predictability. Strategic queue predictions and target gate pushback times to achieve a desired queue length are compared between fast time simulations of CLT surface operations with and without tactical scheduling. The use of variable departure rates as a strategic scheduler input was shown to substantially improve queue predictions over static departure rates. With target queue length calibration, the strategic scheduler can be tuned to produce average delays within one minute of the tactical scheduler. However, root mean square differences between strategic and tactical delays were between 12 and 15 minutes due to the different methods the strategic and tactical schedulers use to predict takeoff times and generate gate pushback clearances. This demonstrates how difficult it is for the strategic scheduler to predict tactical scheduler assigned gate delays on an individual flight basis as the tactical scheduler adjusts departure sequence to accommodate arrival interactions. Strategic/tactical scheduler compatibility may be improved by providing more arrival information to the strategic scheduler and stabilizing tactical scheduler changes to runway sequence in response to arrivals.
Goal-driven modulation of stimulus-driven attentional capture in multiple-cue displays.
Richard, Christian M; Wright, Richard D; Ward, Lawrence M
2003-08-01
Six location-cuing experiments were conducted to examine the goal-driven control of attentional capture in multiple-cue displays. In most of the experiments, the cue display consisted of the simultaneous presentation of a red direct cue that was highly predictive of the target location (the unique cue) and three gray direct cues (the standard cues) that were not predictive of the location. The results indicated that although target responses were faster at all cued locations relative to uncued locations, they were significantly faster at the unique-cue location than at the standard-cue locations. Other results suggest that the faster responses produced by direct cues may be associated with two different components: an attention-related component that can be modulated by goal-driven factors and a nonattentional component that occurs in parallel at multiple direct-cue locations and is minimally affected by the same goal-driven factors.
On scheduling task systems with variable service times
NASA Astrophysics Data System (ADS)
Maset, Richard G.; Banawan, Sayed A.
1993-08-01
Several strategies have been proposed for developing optimal and near-optimal schedules for task systems (jobs consisting of multiple tasks that can be executed in parallel). Most such strategies, however, implicitly assume deterministic task service times. We show that these strategies are much less effective when service times are highly variable. We then evaluate two strategies—one adaptive, one static—that have been proposed for retaining high performance despite such variability. Both strategies are extensions of critical path scheduling, which has been found to be efficient at producing near-optimal schedules. We found the adaptive approach to be quite effective.
Flexible Scheduling to Fit the Firefighters.
ERIC Educational Resources Information Center
Cox, Clarice Robinson
Three flexible scheduling plans were tried in order that firefighters could take regular college courses despite their 24 hours on the 24 off work schedule. Plan one scheduled the firefighters into a regular Monday-Wednesday-Friday class which they attended every other week, making up missed material outside of class. Plan two scheduled special…
Transmission overhaul estimates for partial and full replacement at repair
NASA Technical Reports Server (NTRS)
Savage, M.; Lewicki, D. G.
1991-01-01
Timely transmission overhauls increase in-flight service reliability greater than the calculated design reliabilities of the individual aircraft transmission components. Although necessary for aircraft safety, transmission overhauls contribute significantly to aircraft expense. Predictions of a transmission's maintenance needs at the design stage should enable the development of more cost effective and reliable transmissions in the future. The frequency is estimated of overhaul along with the number of transmissions or components needed to support the overhaul schedule. Two methods based on the two parameter Weibull statistical distribution for component life are used to estimate the time between transmission overhauls. These methods predict transmission lives for maintenance schedules which repair the transmission with a complete system replacement or repair only failed components of the transmission. An example illustrates the methods.
SKYLAB (SL)-3 CREW - TRAINING - ORBITAL WORKSHOP (OWS) TRAINER - JSC
1973-06-19
S73-28411 (February 1973) --- The three members of the prime crew of the third of three scheduled manned Skylab missions (Skylab 4) go through Skylab preflight training in the Mission Training and Simulation Facility at the Johnson Space Center. Astronaut Gerald P. Carr (on right), Skylab 4 commander, is seated at a simulator which represents the control and display console of the Apollo Telescope Mount which is located in the space station's Multiple Docking Adapter. Seated on the left is scientist-astronaut Edward G. Gibson, Skylab 4 science pilot. In the left background is astronaut William R. Pogue, Skylab 4 pilot. (Unmanned Skylab 1 will carry the Skylab space station payload into Earth orbit). Photo credit: NASA
Project Listen Compute Show (LCS) - Marine
2004-02-01
Figure 15. Block diagram of a BB-5. Notice the discrete components between the FPGA and the display connection. All of these are scheduled to be... scheduled to form the core of the next generation projection product. This architecture is expected to scale to true HDTV resolution of 1920 by 1080...flight schedule obtained from a SABRE database in order to offer on-time status. We have developed more sophisticated mechanisms for dealing with
Firefighter Shift Schedules Affect Sleep Quality.
Billings, Joel; Focht, Will
2016-03-01
The aim of this study was to investigate the prevalence and severity of firefighter sleep quality across department shift schedules. Sleep quality was assessed using a Pittsburgh Sleep Quality Index in a sample of 109 male career firefighters from six fire departments in three Southwestern US states. The three shift schedules studied were 24on/48off, 48on/96off, and Kelly. Seventy-three percent of firefighters report poor sleep quality. The 24on/48off shift schedule is associated with the best sleep quality and Kelly is associated with the worst sleep quality. Firefighters working second jobs report significantly poorer sleep quality than those who do not. Shift schedules that disrupt normal circadian rhythms more result in poorer sleep quality, which can lead to less effective emergency response and increased risk to firefighter health and safety.
Alphatome--Enhancing Spatial Reasoning: A Simulation in Two and Three Dimensions
ERIC Educational Resources Information Center
LeClair, Elizabeth E.
2003-01-01
Using refrigerator magnets, foam blocks, ink pads, and modeling clay, students manipulate the letters of the alphabet at multiple angles, reconstructing three-dimensional forms from two-dimensional data. This exercise increases students' spatial reasoning ability, an important component in many scientific disciplines. (Contains 5 figures.)
Scheduling Results for the THEMIS Observation Scheduling Tool
NASA Technical Reports Server (NTRS)
Mclaren, David; Rabideau, Gregg; Chien, Steve; Knight, Russell; Anwar, Sadaat; Mehall, Greg; Christensen, Philip
2011-01-01
We describe a scheduling system intended to assist in the development of instrument data acquisitions for the THEMIS instrument, onboard the Mars Odyssey spacecraft, and compare results from multiple scheduling algorithms. This tool creates observations of both (a) targeted geographical regions of interest and (b) general mapping observations, while respecting spacecraft constraints such as data volume, observation timing, visibility, lighting, season, and science priorities. This tool therefore must address both geometric and state/timing/resource constraints. We describe a tool that maps geometric polygon overlap constraints to set covering constraints using a grid-based approach. These set covering constraints are then incorporated into a greedy optimization scheduling algorithm incorporating operations constraints to generate feasible schedules. The resultant tool generates schedules of hundreds of observations per week out of potential thousands of observations. This tool is currently under evaluation by the THEMIS observation planning team at Arizona State University.
Scheduling Real-Time Mixed-Criticality Jobs
NASA Astrophysics Data System (ADS)
Baruah, Sanjoy K.; Bonifaci, Vincenzo; D'Angelo, Gianlorenzo; Li, Haohan; Marchetti-Spaccamela, Alberto; Megow, Nicole; Stougie, Leen
Many safety-critical embedded systems are subject to certification requirements; some systems may be required to meet multiple sets of certification requirements, from different certification authorities. Certification requirements in such "mixed-criticality" systems give rise to interesting scheduling problems, that cannot be satisfactorily addressed using techniques from conventional scheduling theory. In this paper, we study a formal model for representing such mixed-criticality workloads. We demonstrate first the intractability of determining whether a system specified in this model can be scheduled to meet all its certification requirements, even for systems subject to two sets of certification requirements. Then we quantify, via the metric of processor speedup factor, the effectiveness of two techniques, reservation-based scheduling and priority-based scheduling, that are widely used in scheduling such mixed-criticality systems, showing that the latter of the two is superior to the former. We also show that the speedup factors are tight for these two techniques.
Effects of Behavioral History on Resistance to Change
ERIC Educational Resources Information Center
Doughty, Adam H.; Cirino, Sergio; Mayfield, Kristin H.; da Silva, Stephanie P.; Okouchi, Hiroto; Lattal, Kennon A.
2005-01-01
Two experiments examined whether differential resistance to change would occur under identical variable-interval schedules as a function of a differential behavioral history. In Experiment 1, each of 3 pigeons first pecked at different rates under a multiple variable-ratio differential-reinforcement-of-low-rate schedule. In a subsequent condition,…
NASA Technical Reports Server (NTRS)
Richards, Stephen F.
1991-01-01
Although computerized operations have significant gains realized in many areas, one area, scheduling, has enjoyed few benefits from automation. The traditional methods of industrial engineering and operations research have not proven robust enough to handle the complexities associated with the scheduling of realistic problems. To address this need, NASA has developed the computer-aided scheduling system (COMPASS), a sophisticated, interactive scheduling tool that is in wide-spread use within NASA and the contractor community. Therefore, COMPASS provides no explicit support for the large class of problems in which several people, perhaps at various locations, build separate schedules that share a common pool of resources. This research examines the issue of distributing scheduling, as applied to application domains characterized by the partial ordering of tasks, limited resources, and time restrictions. The focus of this research is on identifying issues related to distributed scheduling, locating applicable problem domains within NASA, and suggesting areas for ongoing research. The issues that this research identifies are goals, rescheduling requirements, database support, the need for communication and coordination among individual schedulers, the potential for expert system support for scheduling, and the possibility of integrating artificially intelligent schedulers into a network of human schedulers.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Weiss, David; Purgert, Robert; Rhudy, Richard
1999-04-21
Some highlights are: (1) Material development, process development, and part validation are occurring simultaneously on a fast track schedule. (2) Prior project activity has resulted in a program emphasis on three components--manifolds, mounting brackets, and motor mounts; and three casting techniques--squeeze casting, pressure die casting, and sand casting. (3) With the project focus, it appears possible to offer manifolds and mounting brackets for automotive qualification testing on a schedule in line with the PNGV Year 2004 goal. (4) Through an iterative process of fly ash treatment, MMC ingot preparation, foundry process refinement, and parts production, both foundries (Eck Industries andmore » Thompson Aluminum Casting Company) are addressing the pre-competitive issues of: (a) Optimum castability with fly ash shapes and sizes; (b) Best mechanical properties derived from fly ash shapes and sizes; (c) Effective fly ash classification processes; (d) Mechanical properties resulting from various casting processes and fly ash formulations. Eck and TAC continued experiments with batch ingot provided by both Eck and the University of Wisconsin at Milwaukee. Castings were run that contained varying amounts of fly ash and different size fractions. Components were cast using cenosphere material to ascertain the effects of squeeze casting and to determine whether the pressure would break the cenospheres. Test parts are currently being machined into substandard test bars for mechanical testing. Also, the affect of heat treatments on ashalloy are being studied through comparison to two lots, one heat treated and one in the ''as cast'' condition.« less
Duval, J; Coyette, F; Seron, X
2008-08-01
This paper describes and evaluates a programme of neuropsychological rehabilitation which aims to improve three sub-components of the working memory central executive: processing load, updating and dual-task monitoring, by the acquisition of three re-organisation strategies (double coding, serial processing and speed reduction). Our programme has two stages: cognitive rehabilitation (graduated exercises subdivided into three sub-programmes each corresponding to a sub-component) which enables the patient to acquire the three specific strategies; and an ecological rehabilitation, including analyses of scenarios and simulations of real-life situations, which aims to transfer the strategies learned to everyday life. The programme also includes information meetings. It was applied to a single case who had working memory deficits after a surgical operation for a cerebral tumour on his left internal temporal ganglioglioma. Multiple baseline tests were used to measure the effectiveness of the rehabilitation. The programme proved to be effective for all three working memory components; a generalisation of its effects to everyday life was observed, and the effects were undiminished three months later.
36 CFR 1225.12 - How are records schedules developed?
Code of Federal Regulations, 2010 CFR
2010-07-01
... activity to identify records series, systems, and nonrecord materials. (c) Determine the appropriate scope of the records schedule items, e.g., individual series/system component, work process, group of related work processes, or broad program area. (d) Evaluate the period of time the agency needs each...
36 CFR 1225.12 - How are records schedules developed?
Code of Federal Regulations, 2011 CFR
2011-07-01
... activity to identify records series, systems, and nonrecord materials. (c) Determine the appropriate scope of the records schedule items, e.g., individual series/system component, work process, group of related work processes, or broad program area. (d) Evaluate the period of time the agency needs each...
36 CFR 1225.12 - How are records schedules developed?
Code of Federal Regulations, 2012 CFR
2012-07-01
... activity to identify records series, systems, and nonrecord materials. (c) Determine the appropriate scope of the records schedule items, e.g., individual series/system component, work process, group of related work processes, or broad program area. (d) Evaluate the period of time the agency needs each...
Cheong, Jadeera P.G.; Lay, Brendan; Razman, Rizal
2016-01-01
This study attempted to present conditions that were closer to the real-world setting of team sports. The primary purpose was to examine the effects of blocked, random and game-based training practice schedules on the learning of the field hockey trap, close dribble and push pass that were practiced in combination. The secondary purpose was to investigate the effects of predictability of the environment on the learning of field hockey sport skills according to different practice schedules. A game-based training protocol represented a form of random practice in an unstable environment and was compared against a blocked and a traditional random practice schedule. In general, all groups improved dribble and push accuracy performance during the acquisition phase when assessed in a closed environment. In the retention phase, there were no differences between the three groups. When assessed in an open skills environment, all groups improved their percentage of successful executions for trapping and passing execution, and improved total number of attempts and total number of successful executions for both dribbling and shooting execution. Between-group differences were detected for dribbling execution with the game-based group scoring a higher number of dribbling successes. The CI effect did not emerge when practicing and assessing multiple sport skills in a closed skill environment, even when the skills were practiced in combination. However, when skill assessment was conducted in a real-world situation, there appeared to be some support for the CI effect. Key points The contextual interference effect was not supported when practicing several skills in combination when the sports skills were assessed in a closed skill environment. There appeared to be some support for the contextual interference effect when sports skills were assessed in an open skill environment, which were similar to a real game situation. A game-based training schedule can be used as an alternative practice schedule as it displayed superior learning compared to a blocked practice schedule when assessed by the game performance test (real-world setting). The game-based training schedule also matched the blocked and random practice schedules in the other tests. PMID:26957940
Cheong, Jadeera P G; Lay, Brendan; Razman, Rizal
2016-03-01
This study attempted to present conditions that were closer to the real-world setting of team sports. The primary purpose was to examine the effects of blocked, random and game-based training practice schedules on the learning of the field hockey trap, close dribble and push pass that were practiced in combination. The secondary purpose was to investigate the effects of predictability of the environment on the learning of field hockey sport skills according to different practice schedules. A game-based training protocol represented a form of random practice in an unstable environment and was compared against a blocked and a traditional random practice schedule. In general, all groups improved dribble and push accuracy performance during the acquisition phase when assessed in a closed environment. In the retention phase, there were no differences between the three groups. When assessed in an open skills environment, all groups improved their percentage of successful executions for trapping and passing execution, and improved total number of attempts and total number of successful executions for both dribbling and shooting execution. Between-group differences were detected for dribbling execution with the game-based group scoring a higher number of dribbling successes. The CI effect did not emerge when practicing and assessing multiple sport skills in a closed skill environment, even when the skills were practiced in combination. However, when skill assessment was conducted in a real-world situation, there appeared to be some support for the CI effect. Key pointsThe contextual interference effect was not supported when practicing several skills in combination when the sports skills were assessed in a closed skill environment.There appeared to be some support for the contextual interference effect when sports skills were assessed in an open skill environment, which were similar to a real game situation.A game-based training schedule can be used as an alternative practice schedule as it displayed superior learning compared to a blocked practice schedule when assessed by the game performance test (real-world setting). The game-based training schedule also matched the blocked and random practice schedules in the other tests.
ERIC Educational Resources Information Center
Foster, T. Mary; Sumpter, Catherine E.; Temple, William; Flevill, Amanda; Poling, Alan
2009-01-01
Concurrent schedules were used to establish 6 hens' preferences for three foods. The resulting biases suggested wheat was preferred over honey-puffed and puffed wheat, and puffed wheat was the least preferred food. The hens then responded under fixed-ratio schedules for each food in 40-min (excluding reinforcer time) sessions, with the response…
Ginsburg, Brett C; Lamb, R J
2015-04-01
In reinstatement studies (a common preclinical procedure for studying relapse), incubation occurs (longer abstinence periods result in more responding). This finding is discordant with the clinical literature. Identifying determinants of incubation could aid in interpreting reinstatement and identifying processes involved in relapse. Reinstated responding was examined in rats trained to respond for ethanol and food under a multiple concurrent schedule (Component 1: ethanol FR5, food FR150; Component 2: ethanol FR5, food FR5-alternating across the 30-min session). Ethanol consumption was then reduced for 1 or 16 sessions either by suspending training (rats remained in home cage) or by providing alternative reinforcement (only Component 2 stimuli and contingencies were presented throughout the session). In the next session, stimuli associated with Component 1 were presented and responses recorded but ethanol and food were never delivered. Two test conditions were studied: fixed-ratio completion either produced ethanol- or food-associated stimuli (signaled) or had no programmed consequence (unsignaled). Incubation of ethanol responding was observed only after suspended training during signaled test sessions. Incubation of food responding was also observed after suspended training. These results are most consistent with incubation resulting from a degradation of feedback functions limiting extinction responding, rather than from increased motivation. Copyright © 2015 Elsevier B.V. All rights reserved.
Assessment of Spatial Navigation and Docking Performance During Simulated Rover Tasks
NASA Technical Reports Server (NTRS)
Wood, S. J.; Dean, S. L.; De Dios, Y. E.; Moore, S. T.
2010-01-01
INTRODUCTION: Following long-duration exploration transits, pressurized rovers will enhance surface mobility to explore multiple sites across Mars and other planetary bodies. Multiple rovers with docking capabilities are envisioned to expand the range of exploration. However, adaptive changes in sensorimotor and cognitive function may impair the crew s ability to safely navigate and perform docking tasks shortly after transition to the new gravitoinertial environment. The primary goal of this investigation is to quantify post-flight decrements in spatial navigation and docking performance during a rover simulation. METHODS: Eight crewmembers returning from the International Space Station will be tested on a motion simulator during four pre-flight and three post-flight sessions over the first 8 days following landing. The rover simulation consists of a serial presentation of discrete tasks to be completed within a scheduled 10 min block. The tasks are based on navigating around a Martian outpost spread over a 970 sq m terrain. Each task is subdivided into three components to be performed as quickly and accurately as possible: (1) Perspective taking: Subjects use a joystick to indicate direction of target after presentation of a map detailing current orientation and location of the rover with the task to be performed. (2) Navigation: Subjects drive the rover to the desired location while avoiding obstacles. (3) Docking: Fine positioning of the rover is required to dock with another object or align a camera view. Overall operator proficiency will be based on how many tasks the crewmember can complete during the 10 min time block. EXPECTED RESULTS: Functionally relevant testing early post-flight will develop evidence regarding the limitations to early surface operations and what countermeasures are needed. This approach can be easily adapted to a wide variety of simulated vehicle designs to provide sensorimotor assessments for other operational and civilian populations.
2007-10-01
KENNEDY SPACE CENTER, FLA. -- In the Space Station Processing Facility at NASA's Kennedy Space Center, technicians help guide the starboard arm of the Special Purpose Dexterous Manipulator, known as Dextre, into place for installation on the base. Dextre is a sophisticated dual-armed robot, which is part of Canada's contribution to the International Space Station (ISS). Along with Canadarm2, whose technical name is the Space Station Remote Manipulator System, and a moveable work platform called the Mobile Base System, these three elements form a robotic system called the Mobile Servicing System, or MSS. The three components have been designed to work together or independently. Dextre is part of the payload scheduled on mission STS-123, targeted to launch Feb. 14. Photo credit: NASA/George Shelton
2007-10-01
KENNEDY SPACE CENTER, FLA. -- In the Space Station Processing Facility at NASA's Kennedy Space Center, the starboard arm of the Special Purpose Dexterous Manipulator, known as Dextre, is ready to be installed on the base. Dextre is a sophisticated dual-armed robot, which is part of Canada's contribution to the International Space Station ISS. Along with Canadarm2, whose technical name is the Space Station Remote Manipulator System, and a moveable work platform called the Mobile Base System, these three elements form a robotic system called the Mobile Servicing System, or MSS. The three components have been designed to work together or independently. Dextre is part of the payload scheduled on mission STS-123, targeted to launch Feb. 14. Photo credit: NASA/George Shelton
2007-10-01
KENNEDY SPACE CENTER, FLA. -- In the Space Station Processing Facility at NASA's Kennedy Space Center, technicians help guide the starboard arm of the Special Purpose Dexterous Manipulator, known as Dextre, into place for installation on the base. Dextre is a sophisticated dual-armed robot, which is part of Canada's contribution to the International Space Station (ISS). Along with Canadarm2, whose technical name is the Space Station Remote Manipulator System, and a moveable work platform called the Mobile Base System, these three elements form a robotic system called the Mobile Servicing System, or MSS. The three components have been designed to work together or independently. Dextre is part of the payload scheduled on mission STS-123, targeted to launch Feb. 14. Photo credit: NASA/George Shelton
2007-10-01
KENNEDY SPACE CENTER, FLA. -- In the Space Station Processing Facility at NASA's Kennedy Space Center, the starboard arm of the Special Purpose Dexterous Manipulator, known as Dextre, is moved across the facility. The arm will be installed on the base. Dextre is a sophisticated dual-armed robot, which is part of Canada's contribution to the International Space Station (ISS). Along with Canadarm2, whose technical name is the Space Station Remote Manipulator System, and a moveable work platform called the Mobile Base System, these three elements form a robotic system called the Mobile Servicing System, or MSS. The three components have been designed to work together or independently. Dextre is part of the payload scheduled on mission STS-123, targeted to launch Feb. 14. Photo credit: NASA/George Shelton
Marching to the beat of Moore's Law
NASA Astrophysics Data System (ADS)
Borodovsky, Yan
2006-03-01
Area density scaling in integrated circuits, defined as transistor count per unit area, has followed the famous observation-cum-prediction by Gordon Moore for many generations. Known as "Moore's Law" which predicts density doubling every 18-24 month, it has provided all important synchronizing guidance and reference for tools and materials suppliers, IC manufacturers and their customers as to what minimal requirements their products and services need to meet to satisfy technical and financial expectations in support of the infrastructure required for the development and manufacturing of corresponding technology generation nodes. Multiple lithography solutions are usually under considerations for any given node. In general, three broad classes of solutions are considered: evolutionary - technology that is extension of existing technology infrastructure at similar or slightly higher cost and risk to schedule; revolutionary - technology that discards significant parts of the existing infrastructure at similar cost, higher risk to schedule but promises higher capability as compared to the evolutionary approach; and last but not least, disruptive - approach that as a rule promises similar or better capabilities, much lower cost and wholly unpredictable risk to schedule and products yields. This paper examines various lithography approaches, their respective merits against criteria of respective infrastructure availability, affordability and risk to IC manufacturer's schedules and strategy involved in developing and selecting best solution in an attempt to sort out key factors that will impact the decision on the lithography choice for large-scale manufacturing for the future technology nodes.
MacDuff, G S; Krantz, P J; McClannahan, L E
1993-01-01
We used a graduated guidance procedure to teach 4 boys with autism to follow photographic activity schedules to increase on-task and on-schedule behavior. The multiple baseline across participants design included baseline, teaching, maintenance, resequencing of photographs, and generalization to novel photographs phases. The results indicated that photographic activity schedules (albums depicting after-school activities) produced sustained engagement, and skills generalized to a new sequence of photographs and to new photographs. The acquisition of schedule-following skills enabled these children with severe developmental disabilities to display lengthy response chains, independently change activities, and change activities in different group home settings in the absence of immediate supervision and prompts from others. PMID:8473261
Conflict-Aware Scheduling Algorithm
NASA Technical Reports Server (NTRS)
Wang, Yeou-Fang; Borden, Chester
2006-01-01
conflict-aware scheduling algorithm is being developed to help automate the allocation of NASA s Deep Space Network (DSN) antennas and equipment that are used to communicate with interplanetary scientific spacecraft. The current approach for scheduling DSN ground resources seeks to provide an equitable distribution of tracking services among the multiple scientific missions and is very labor intensive. Due to the large (and increasing) number of mission requests for DSN services, combined with technical and geometric constraints, the DSN is highly oversubscribed. To help automate the process, and reduce the DSN and spaceflight project labor effort required for initiating, maintaining, and negotiating schedules, a new scheduling algorithm is being developed. The scheduling algorithm generates a "conflict-aware" schedule, where all requests are scheduled based on a dynamic priority scheme. The conflict-aware scheduling algorithm allocates all requests for DSN tracking services while identifying and maintaining the conflicts to facilitate collaboration and negotiation between spaceflight missions. These contrast with traditional "conflict-free" scheduling algorithms that assign tracks that are not in conflict and mark the remainder as unscheduled. In the case where full schedule automation is desired (based on mission/event priorities, fairness, allocation rules, geometric constraints, and ground system capabilities/ constraints), a conflict-free schedule can easily be created from the conflict-aware schedule by removing lower priority items that are in conflict.
Dack, Charlotte; Reed, Phil; McHugh, Louise
2010-11-01
The aim of the four present experiments was to explore how different schedules of reinforcement influence schedule-induced behavior, their impact on evaluative ratings given to conditioned stimuli associated with each schedule through evaluative conditioning, and the transfer of these evaluations through derived stimulus networks. Experiment 1 compared two contrasting response reinforcement rules (variable ratio [VR], variable interval [VI]). Experiment 2 varied the response to reinforcement rule between two schedules but equated the outcome to response rate (differential reinforcement of high rate [DRH] vs. VR). Experiment 3 compared molar and molecular aspects of contingencies of reinforcement (tandem VIVR vs. tandem VRVI). Finally, Experiment 4 employed schedules that induced low rates of responding to determine whether, under these circumstances, responses were more sensitive to the molecular aspects of a schedule (differential reinforcement of low rate [DRL] vs. VI). The findings suggest that the transfer of evaluative functions is determined mainly by differences in response rate between the schedules and the molar aspects of the schedules. However, when neither schedule was based on a strong response reinforcement rule, the transfer of evaluative judgments came under the control of the molecular aspects of the schedule.
Klerman, Elizabeth B; Beckett, Scott A; Landrigan, Christopher P
2016-09-13
In 2011 the U.S. Accreditation Council for Graduate Medical Education began limiting first year resident physicians (interns) to shifts of ≤16 consecutive hours. Controversy persists regarding the effectiveness of this policy for reducing errors and accidents while promoting education and patient care. Using a mathematical model of the effects of circadian rhythms and length of time awake on objective performance and subjective alertness, we quantitatively compared predictions for traditional intern schedules to those that limit work to ≤ 16 consecutive hours. We simulated two traditional schedules and three novel schedules using the mathematical model. The traditional schedules had extended duration work shifts (≥24 h) with overnight work shifts every second shift (including every third night, Q3) or every third shift (including every fourth night, Q4) night; the novel schedules had two different cross-cover (XC) night team schedules (XC-V1 and XC-V2) and a Rapid Cycle Rotation (RCR) schedule. Predicted objective performance and subjective alertness for each work shift were computed for each individual's schedule within a team and then combined for the team as a whole. Our primary outcome was the amount of time within a work shift during which a team's model-predicted objective performance and subjective alertness were lower than that expected after 16 or 24 h of continuous wake in an otherwise rested individual. The model predicted fewer hours with poor performance and alertness, especially during night-time work hours, for all three novel schedules than for either the traditional Q3 or Q4 schedules. Three proposed schedules that eliminate extended shifts may improve performance and alertness compared with traditional Q3 or Q4 schedules. Predicted times of worse performance and alertness were at night, which is also a time when supervision of trainees is lower. Mathematical modeling provides a quantitative comparison approach with potential to aid residency programs in schedule analysis and redesign.
75 FR 67054 - Listing of Approved Drug Products Containing Dronabinol in Schedule III
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-01
... dronabinol extracted from Cannabis sativa (i.e. naturally-derived), is identical to synthetically-produced... psychoactive component of the cannabis plant (marijuana). THC, as a general category, is listed in schedule I... capsule form containing natural dronabinol (derived from the cannabis plant) or synthetic dronabinol...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-16
... Area ICD International Classification of Diseases IMRT Intensity Modulated Radiation Therapy IOM... Stereotactic body radiation therapy SGR Sustainable growth rate TC Technical component TIN Tax identification... Clinical Lab Fee Schedule, which is unaffected by the misvalued code initiative. Radiation therapy centers...
A Principal Components Analysis of the Rathus Assertiveness Schedule.
ERIC Educational Resources Information Center
Law, H. G.; And Others
1979-01-01
Investigated the adequacy of the Rathus Assertiveness Schedule (RAS) as a global measure of assertiveness. Analysis indicated that the RAS does not provide a unidimensional index of assertiveness, but rather measures a number of factors including situation-specific assertive behavior, aggressiveness, and a more general assertiveness. (Author)
1987-01-16
Management System (NOHIMS) Industrial Hygiene (IH) Component database in order to perform these functions: (1) enroll and remove employees from Medical...The Medical Examination Scheduling (MES) module consists of a list of options that allow users to access the Navy Occupational Health Information
1987-01-16
Management System (HOHIMS) Industrial Hygiene (IH) Component database in order to perform these functions: (1) enroll and remove employees from Medical...The Medical Examination Scheduling (MES) module consists of a list of options that allow users to access the Navy Occupational Health Information
Prenatal ethanol weakens the efficacy of reinforcers for adult mice.
Gentry, G D; Middaugh, L D
1988-02-01
Pregnant C57BL/6cr mice were fed a liquid diet containing 20% of the total calories from either ethanol (E) or sucrose (S) for gestation days 5-17. Adult male and female (six of each from both prenatal-treatment groups) offspring were tested under various schedules of food reinforcement. The first phase was a test of fixed-ratio (FR) acquisition in which the required number of responses per unit of reinforcement was increased from 1 to 20 to 100. Prenatal ethanol exposure interacted with other factors to produce an acquisition deficit. The second phase involved responding under extinction (Ext). Under standard Ext procedures there were no prenatal-ethanol effects; however, when a conditioned reinforcer was superimposed on an FR 5, the E males did not increase their rates as much as the S males. Finally, under a multiple FR 5 DRO 15-sec (differential-reinforcement-of-other-behavior) arrangement, prenatal-ethanol effects were found in each component. For the FR 5 component, prenatal ethanol eliminated the sex differences found in the S subjects. For the DRO 15-sec component, prenatal ethanol elevated response rates. The results indicate a general decreased efficacy of positive reinforcement in adult mice following prenatal ethanol exposure.
NASA Astrophysics Data System (ADS)
Wu, Y.; Luo, Z.; Zhou, H.; Xu, C.
2017-12-01
Regional gravity field recovery is of great importance for understanding ocean circulation and currents in oceanography and investigating the structure of the lithosphere in geophysics. Under the framework of remove-compute-restore methodology (RCR), a regional approach using spherical radial basis functions (SRBFs) is set up for gravity field determination using the GOCE (Gravity Field and Steady-State Ocean Circulation Explorer) gravity gradient tensor, heterogeneous gravimetry and altimetry measurements. The additional value on regional model introduced by GOCE data is validated and quantified. Numerical experiments in a western European region show that the effects introduced by GOCE data display as long-wavelength patterns on the centimeter scale in terms of quasi-geoid heights, which may allow to highlight and reduce the remaining long-wavelength errors and biases in ground-based data and improve the regional model. The accuracy of the gravimetric quasi-geoid computed with a combination of three diagonal components is improved by 0.6 cm (0.5 cm) in the Netherlands (Belgium), compared to that derived from gravimetry and altimetry data alone, when GOCO05s is used as the reference model. Performances of different diagonal components and their combinations are not identical; the solution with vertical gradients shows highest quality when a single component is used. Incorporation of multiple components further improves the model, and the combination of three components shows the best fit to GPS/leveling data. Moreover, the contributions introduced by different components are heterogeneous in terms of spatial coverage and magnitude, although similar structures occur in the spatial domain. Contributions introduced by the vertical components have the most significant effects when a single component is applied. Combination of multiple components further magnifies these effects and improves the solutions, and the incorporation of three components has the most prominent effects. This work is supported by the State Scholarship Fund from Chinese Scholarship Council (201306270014), China Postdoctoral Science Foundation (No.2016M602301), and the National Natural Science Foundation of China (No. 41374023).
Temporal planning for transportation planning and scheduling
NASA Technical Reports Server (NTRS)
Frederking, Robert E.; Muscettola, Nicola
1992-01-01
In this paper we describe preliminary work done in the CORTES project, applying the Heuristic Scheduling Testbed System (HSTS) to a transportation planning and scheduling domain. First, we describe in more detail the transportation problems that we are addressing. We then describe the fundamental characteristics of HSTS and we concentrate on the representation of multiple capacity resources. We continue with a more detailed description of the transportation planning problem that we have initially addressed in HSTS and of its solution. Finally we describe future directions for our research.
Viidanoja, Jyrki
2015-09-15
A new, sensitive and selective liquid chromatography-electrospray ionization-tandem mass spectrometric (LC-ESI-MS/MS) method was developed for the analysis of Phospholipids (PLs) in bio-oils and fats. This analysis employs hydrophilic interaction liquid chromatography-scheduled multiple reaction monitoring (HILIC-sMRM) with a ZIC-cHILIC column. Eight PL class selective internal standards (homologs) were used for the semi-quantification of 14 PL classes for the first time. More than 400 scheduled MRMs were used for the measurement of PLs with a run time of 34min. The method's performance was evaluated for vegetable oil, animal fat and algae oil. The averaged within-run precision and between-run precision were ≤10% for all of the PL classes that had a direct homologue as an internal standard. The method accuracy was generally within 80-120% for the tested PL analytes in all three sample matrices. Copyright © 2015 Elsevier B.V. All rights reserved.
Progress of Crew Autonomous Scheduling Test (CAST) On the ISS
NASA Technical Reports Server (NTRS)
Healy, Matthew; Marquez, Jessica; Hillenius, Steven; Korth, David; Bakalyar, Lauren Rush; Woodbury, Neil; Larsen, Crystal M.; Bates, Shelby; Kockler, Mikayla; Rhodes, Brooke;
2017-01-01
The United States space policy is evolving toward missions beyond low Earth orbit. In an effort to meet that policy, NASA has recognized Autonomous Mission Operations (AMO) as a valuable capability. Identified within AMO capabilities is the potential for autonomous planning and replanning during human spaceflight operations. That is allowing crew members to collectively or individually participate in the development of their own schedules. Currently, dedicated mission operations planners collaborate with international partners to create daily plans for astronauts aboard the International Space Station (ISS), taking into account mission requirements, ground rules, and various vehicle and payload constraints. In future deep space operations the crew will require more independence from ground support due to communication transmission delays. Furthermore, crew members who are provided with the capability to schedule their own activities are able to leverage direct experience operating in the space environment, and possibly maximize their efficiency. CAST (Crew Autonomous Scheduling Test) is an ISS investigation designed to analyze three important hypotheses about crew autonomous scheduling. First, given appropriate inputs, the crew is able to create and execute a plan in a reasonable period of time without impacts to mission success. Second, the proximity of the planner, in this case the crew, to the planned operations increases their operational efficiency. Third, crew members are more satisfied when given a role in plan development. This presentation shows the progress done in this study with a single astronaut test subject participating in five CAST sessions. CAST is a technology demonstration payload sponsored by the ISS Research Science and Technology Office, and performed by experts in Mission Operations Planning from the Flight Operations Directorate at NASA Johnson Space Center, and researchers across multiple NASA centers.
Longley, Susan L; Watson, David; Noyes, Russell; Yoder, Kevin
2006-01-01
A dimensional and psychometrically informed taxonomy of anxiety is emerging, but the specific and nonspecific dimensions of panic and phobic anxiety require greater clarification. In this study, confirmatory factor analyses of data from a sample of 438 college students were used to validate a model of panic and phobic anxiety with six content factors; multiple scales from self-report measures were indicators of each model component. The model included a nonspecific component of (1) neuroticism and two specific components of panic attack, (2) physiological hyperarousal, and (3) anxiety sensitivity. The model also included three phobia components of (4) classically defined agoraphobia, (5) social phobia, and (6) blood-injection phobia. In these data, agoraphobia correlated more strongly with both the social phobia and blood phobia components than with either the physiological hyperarousal or the anxiety sensitivity components. These findings suggest that the association between panic attacks and agoraphobia warrants greater attention.
Areas influenced by multiple edges and their implications in fragmented landscapes
Qinglin Li; Jiquan Chen; Bo Song; Jacob L. LaCroix; Mary K. Breese; John A. Radmacher
2007-01-01
We introduced a new approach for delineating areas of multiple edge influence (AMEI) within a fragmented landscape using a geographic information system (GIS). AMEI was defined as the interface that is affected by more than two neighboring patch types. We decomposed AMEI into three components: AMEI1, the area where one patch type meets a different patch type; AMEI2,...
Stabilized single-injection inactivated polio vaccine elicits a strong neutralizing immune response.
Tzeng, Stephany Y; McHugh, Kevin J; Behrens, Adam M; Rose, Sviatlana; Sugarman, James L; Ferber, Shiran; Langer, Robert; Jaklenec, Ana
2018-05-21
Vaccination in the developing world is hampered by limited patient access, which prevents individuals from receiving the multiple injections necessary for protective immunity. Here, we developed an injectable microparticle formulation of the inactivated polio vaccine (IPV) that releases multiple pulses of stable antigen over time. To accomplish this, we established an IPV stabilization strategy using cationic polymers for pH modulation to enhance traditional small-molecule-based stabilization methods. We investigated the mechanism of this strategy and showed that it was broadly applicable to all three antigens in IPV. Our lead formulations released two bursts of IPV 1 month apart, mimicking a typical vaccination schedule in the developing world. One injection of the controlled-release formulations elicited a similar or better neutralizing response in rats, considered the correlate of protection in humans, than multiple injections of liquid vaccine. This single-administration vaccine strategy has the potential to improve vaccine coverage in the developing world. Copyright © 2018 the Author(s). Published by PNAS.
Stabilized single-injection inactivated polio vaccine elicits a strong neutralizing immune response
Tzeng, Stephany Y.; McHugh, Kevin J.; Behrens, Adam M.; Rose, Sviatlana; Sugarman, James L.; Ferber, Shiran; Jaklenec, Ana
2018-01-01
Vaccination in the developing world is hampered by limited patient access, which prevents individuals from receiving the multiple injections necessary for protective immunity. Here, we developed an injectable microparticle formulation of the inactivated polio vaccine (IPV) that releases multiple pulses of stable antigen over time. To accomplish this, we established an IPV stabilization strategy using cationic polymers for pH modulation to enhance traditional small-molecule–based stabilization methods. We investigated the mechanism of this strategy and showed that it was broadly applicable to all three antigens in IPV. Our lead formulations released two bursts of IPV 1 month apart, mimicking a typical vaccination schedule in the developing world. One injection of the controlled-release formulations elicited a similar or better neutralizing response in rats, considered the correlate of protection in humans, than multiple injections of liquid vaccine. This single-administration vaccine strategy has the potential to improve vaccine coverage in the developing world. PMID:29784798
Scheduler for multiprocessor system switch with selective pairing
Gara, Alan; Gschwind, Michael Karl; Salapura, Valentina
2015-01-06
System, method and computer program product for scheduling threads in a multiprocessing system with selective pairing of processor cores for increased processing reliability. A selective pairing facility is provided that selectively connects, i.e., pairs, multiple microprocessor or processor cores to provide one highly reliable thread (or thread group). The method configures the selective pairing facility to use checking provide one highly reliable thread for high-reliability and allocate threads to corresponding processor cores indicating need for hardware checking. The method configures the selective pairing facility to provide multiple independent cores and allocate threads to corresponding processor cores indicating inherent resilience.
ERIC Educational Resources Information Center
Hansmann, Ralf
2009-01-01
A university Environmental Sciences curriculum is described against the background of requirements for environmental problem solving for sustainability and then analyzed using data from regular surveys of graduates (N = 373). Three types of multiple regression models examine links between qualifications and curriculum components in order to derive…
HOST payload for STS-95 being moved into SSPF
NASA Technical Reports Server (NTRS)
1998-01-01
The Hubble Space Telescope Orbiting Systems Test (HOST) is checked out by technicians in the Space Shuttle Processing Facility. One of the payloads on the STS-95 mission, the HOST platform is carrying four experiments to validate components planned for installation during the third Hubble Space Telescope servicing mission and to evaluate new technologies in an earth orbiting environment. The STS-95 mission is scheduled to launch Oct. 29. It will carry three other payloads: the Spartan solar- observing deployable spacecraft, the International Extreme Ultraviolet Hitchhiker, and the SPACEHAB single module with experiments on space flight and the aging process.
HOST payload for STS-95 being moved into SSPF
NASA Technical Reports Server (NTRS)
1998-01-01
Workers watch as the Hubble Space Telescope Orbiting Systems Test (HOST)is moved inside the Space Shuttle Processing Facility. The HOST platform, one of the payloads on the STS-95 mission, is carrying four experiments to validate components planned for installation during the third Hubble Space Telescope servicing mission and to evaluate new technologies in an earth orbiting environment. The STS-95 mission is scheduled to launch Oct. 29. It will carry three other payloads: the Spartan solar-observing deployable spacecraft, the International Extreme Ultraviolet Hitchhiker, and the SPACEHAB single module with experiments on space flight and the aging process.
Earth resources instrumentation for the Space Station Polar Platform
NASA Technical Reports Server (NTRS)
Donohoe, Martin J.; Vane, Deborah
1986-01-01
The spacecraft and payloads of the Space Station Polar Platform program are described in a brief overview. Present plans call for one platform in a descending morning-equator-crossing orbit at 824 km and two or three platforms in ascending afternoon-crossing orbits at 542-824 km. The components of the NASA Earth Observing System (EOS) and NOAA payloads are listed in tables and briefly characterized, and data-distribution requirements and the mission development schedule are discussed. A drawing of the platform, a graph showing the spectral coverage of the EOS instruments, and a glossary of acronyms are provided.
1998-09-04
Workers watch as the Hubble Space Telescope Orbiting Systems Test (HOST)is moved inside the Space Shuttle Processing Facility. The HOST platform, one of the payloads on the STS-95 mission, is carrying four experiments to validate components planned for installation during the third Hubble Space Telescope servicing mission and to evaluate new technologies in an earth orbiting environment. The STS-95 mission is scheduled to launch Oct. 29. It will carry three other payloads: the Spartan solar-observing deployable spacecraft, the International Extreme Ultraviolet Hitchhiker, and the SPACEHAB single module with experiments on space flight and the aging process
1998-09-04
The Hubble Space Telescope Orbiting Systems Test (HOST)is being raised to a workstand by technicians in the Space Shuttle Processing Facility. One of the payloads on the STS-95 mission, the HOST platform is carrying four experiments to validate components planned for installation during the third Hubble Space Telescope servicing mission and to evaluate new technologies in an earth orbiting environment. The STS-95 mission is scheduled to launch Oct. 29. It will carry three other payloads: the Spartan solar-observing deployable spacecraft, the International Extreme Ultraviolet Hitchhiker, and the SPACEHAB single module with experiments on space flight and the aging process
1998-09-04
KENNEDY SPACE CENTER, FLA. -- The Hubble Space Telescope Orbiting Systems Test (HOST) is checked out by technicians in the Space Shuttle Processing Facility. One of the payloads on the STS-95 mission, the HOST platform is carrying four experiments to validate components planned for installation during the third Hubble Space Telescope servicing mission and to evaluate new technologies in an earth orbiting environment. The STS-95 mission is scheduled to launch Oct. 29. It will carry three other payloads: the Spartan solar-observing deployable spacecraft, the International Extreme Ultraviolet Hitchhiker, and the SPACEHAB single module with experiments on space flight and the aging process
Kable, Ashley K; Levett-Jones, Tracy L; Arthur, Carol; Reid-Searl, Kerry; Humphreys, Melanie; Morris, Sara; Walsh, Pauline; Witton, Nicola J
2018-01-01
The aim of this paper is to report the results of a cross-national study that evaluated a range of simulation sessions using an observation schedule developed from evidence-based quality indicators. Observational data were collected from 17 simulation sessions conducted for undergraduate nursing students at three universities in Australia and the United Kingdom. The observation schedule contained 27 questions that rated simulation quality. Data were collected by direct observation and from video recordings of the simulation sessions. Results indicated that the highest quality scores were for provision of learning objectives prior to the simulation session (90%) and debriefing (72%). Student preparatiosn and orientation (67%) and perceived realism and fidelity (67%) were scored lower than other components of the simulation sessions. This observational study proved to be an effective strategy to identify areas of strength and those needing further development to improve simulation sessions. Copyright © 2017 Elsevier Ltd. All rights reserved.
NASA Technical Reports Server (NTRS)
Clare, Loren; Clement, B.; Gao, J.; Hutcherson, J.; Jennings, E.
2006-01-01
Described recent development of communications protocols, services, and associated tools targeted to reduce risk, reduce cost and increase efficiency of IND infrastructure and supported mission operations. Space-based networking technologies developed were: a) Provide differentiated quality of service (QoS) that will give precedence to traffic that users have selected as having the greatest importance and/or time-criticality; b) Improve the total value of information to users through the use of QoS prioritization techniques; c) Increase operational flexibility and improve command-response turnaround; d) Enable new class of networked and collaborative science missions; e) Simplify applications interfaces to communications services; and f) Reduce risk and cost from a common object model and automated scheduling and communications protocols. Technologies are described in three general areas: communications scheduling, middleware, and protocols. Additionally developed simulation environment, which provides comprehensive, quantitative understanding of the technologies performance within overall, evolving architecture, as well as ability to refine & optimize specific components.
Immunization Schedules for Preteens and Teens
... Immunization Schedule for Preteens and Teens (7 through 18 Years) Recommend on Facebook Tweet Share Compartir On ... a Catch-Up or Accelerated Schedule Birth through 18 Years In three easy steps, you can use ...
Every three-hour versus every six-hour oral feeding in preterm infants: a randomised clinical trial.
Gray, Megan M; Medoff-Cooper, Barbara; Enlow, Elizabeth M; Mukhopadhyay, Sagori; DeMauro, Sara B
2017-02-01
This trial compares two oral feeding schedules, every three-hour and every six-hour oral feeding attempts, to determine which schedule allows for more rapid attainment of full oral feeding in preterm infants. Infants born at ≤33-week gestation were randomly assigned to receive oral feeding every three hours or every six hours if feeding cues were present. The primary outcome was time to full oral feeding; secondary outcomes include respiratory and apnoea rates, growth and length of stay. A total of 55 infants were recruited. There was no difference between the groups in the primary or secondary outcomes. For preterm infants fed when oral feeding cues are present, an every six-hour schedule did not alter the time to full oral feeding and had no effect on rates of tachypnoea, apnoea or length of hospital stay compared to every three-hour feeding schedule. An every six-hour oral feeding schedule led to only small reductions in number of oral feeding attempts per day. ©2016 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.
OGUPSA sensor scheduling architecture and algorithm
NASA Astrophysics Data System (ADS)
Zhang, Zhixiong; Hintz, Kenneth J.
1996-06-01
This paper introduces a new architecture for a sensor measurement scheduler as well as a dynamic sensor scheduling algorithm called the on-line, greedy, urgency-driven, preemptive scheduling algorithm (OGUPSA). OGUPSA incorporates a preemptive mechanism which uses three policies, (1) most-urgent-first (MUF), (2) earliest- completed-first (ECF), and (3) least-versatile-first (LVF). The three policies are used successively to dynamically allocate and schedule and distribute a set of arriving tasks among a set of sensors. OGUPSA also can detect the failure of a task to meet a deadline as well as generate an optimal schedule in the sense of minimum makespan for a group of tasks with the same priorities. A side benefit is OGUPSA's ability to improve dynamic load balance among all sensors while being a polynomial time algorithm. Results of a simulation are presented for a simple sensor system.
Nontraditional work schedules for pharmacists.
Mahaney, Lynnae; Sanborn, Michael; Alexander, Emily
2008-11-15
Nontraditional work schedules for pharmacists at three institutions are described. The demand for pharmacists and health care in general continues to increase, yet significant material changes are occurring in the pharmacy work force. These changing demographics, coupled with historical vacancy rates and turnover trends for pharmacy staff, require an increased emphasis on workplace changes that can improve staff recruitment and retention. At William S. Middleton Memorial Veterans Affairs Hospital in Madison, Wisconsin, creative pharmacist work schedules and roles are now mainstays to the recruitment and retention of staff. The major challenge that such scheduling presents is the 8 hours needed to prepare a six-week schedule. Baylor Medical Center at Grapevine in Dallas, Texas, has a total of 45 pharmacy employees, and slightly less than half of the 24.5 full-time-equivalent staff work full-time, with most preferring to work one, two, or three days per week. As long as the coverage needs of the facility are met, Envision Telepharmacy in Alpine, Texas, allows almost any scheduling arrangement preferred by individual pharmacists or the pharmacist group covering the facility. Staffing involves a great variety of shift lengths and intervals, with shifts ranging from 2 to 10 hours. Pharmacy leaders must be increasingly aware of opportunities to provide staff with unique scheduling and operational enhancements that can provide for a better work-life balance. Compressed workweeks, job-sharing, and team scheduling were the most common types of alternative work schedules implemented at three different institutions.
1980-05-02
for rebuild. "* The rapid buildup in RVN without mobilizing the Reserve Component made it necessary to draw on materiel and equipment in or scheduled ...been restored to service by 1957. By 1960 the system within RVN was operating both scheduled freight and passenger trains on mucii)of the line...established under a concept approved in April 1963 to provide a centralized source of logistic data for the Pacific Theater. It was scheduled to be
NASA Technical Reports Server (NTRS)
Muscettola, Nicola; Smith, Steven S.
1996-01-01
This final report summarizes research performed under NASA contract NCC 2-531 toward generalization of constraint-based scheduling theories and techniques for application to space telescope observation scheduling problems. Our work into theories and techniques for solution of this class of problems has led to the development of the Heuristic Scheduling Testbed System (HSTS), a software system for integrated planning and scheduling. Within HSTS, planning and scheduling are treated as two complementary aspects of the more general process of constructing a feasible set of behaviors of a target system. We have validated the HSTS approach by applying it to the generation of observation schedules for the Hubble Space Telescope. This report summarizes the HSTS framework and its application to the Hubble Space Telescope domain. First, the HSTS software architecture is described, indicating (1) how the structure and dynamics of a system is modeled in HSTS, (2) how schedules are represented at multiple levels of abstraction, and (3) the problem solving machinery that is provided. Next, the specific scheduler developed within this software architecture for detailed management of Hubble Space Telescope operations is presented. Finally, experimental performance results are given that confirm the utility and practicality of the approach.
Automation Improves Schedule Quality and Increases Scheduling Efficiency for Residents.
Perelstein, Elizabeth; Rose, Ariella; Hong, Young-Chae; Cohn, Amy; Long, Micah T
2016-02-01
Medical resident scheduling is difficult due to multiple rules, competing educational goals, and ever-evolving graduate medical education requirements. Despite this, schedules are typically created manually, consuming hours of work, producing schedules of varying quality, and yielding negative consequences for resident morale and learning. To determine whether computerized decision support can improve the construction of residency schedules, saving time and improving schedule quality. The Optimized Residency Scheduling Assistant was designed by a team from the University of Michigan Department of Industrial and Operations Engineering. It was implemented in the C.S. Mott Children's Hospital Pediatric Emergency Department in the 2012-2013 academic year. The 4 metrics of schedule quality that were compared between the 2010-2011 and 2012-2013 academic years were the incidence of challenging shift transitions, the incidence of shifts following continuity clinics, the total shift inequity, and the night shift inequity. All scheduling rules were successfully incorporated. Average schedule creation time fell from 22 to 28 hours to 4 to 6 hours per month, and 3 of 4 metrics of schedule quality significantly improved. For the implementation year, the incidence of challenging shift transitions decreased from 83 to 14 (P < .01); the incidence of postclinic shifts decreased from 72 to 32 (P < .01); and the SD of night shifts dropped by 55.6% (P < .01). This automated shift scheduling system improves the current manual scheduling process, reducing time spent and improving schedule quality. Embracing such automated tools can benefit residency programs with shift-based scheduling needs.
Fu, Yunhai; Ma, Lin; Xu, Yubin
2015-01-01
In spectrum aggregation (SA), two or more component carriers (CCs) of different bandwidths in different bands can be aggregated to support a wider transmission bandwidth. The scheduling delay is the most important design constraint for the broadband wireless trunking (BWT) system, especially in the cognitive radio (CR) condition. The current resource scheduling schemes for spectrum aggregation become questionable and are not suitable for meeting the challenge of the delay requirement. Consequently, the authors propose a novel component carrier configuration and switching scheme for real-time traffic (RT-CCCS) to satisfy the delay requirement in the CR-based SA system. In this work, the authors consider a sensor-network-assisted CR network. The authors first introduce a resource scheduling structure for SA in the CR condition. Then the proposed scheme is analyzed in detail. Finally, simulations are carried out to verify the analysis on the proposed scheme. Simulation results prove that our proposed scheme can satisfy the delay requirement in the CR-based SA system. PMID:26393594
Enabling New Operations Concepts for Lunar and Mars Exploration
NASA Astrophysics Data System (ADS)
Jaap, John; Maxwell, Theresa
2005-02-01
The planning and scheduling of human space activities is an expensive and time-consuming task that seldom provides the crew with the control, flexibility, or insight that they need. During the past thirty years, scheduling software has seen only incremental improvements; however, software limitations continue to prevent even evolutionary improvements in the ``operations concept'' that is used for human space missions. Space missions are planned on the ground long before they are executed in space, and the crew has little input or influence on the schedule. In recent years the crew has been presented with a ``job jar'' of activities that they can do whenever they have time, but the contents of the jar is limited to tasks that do not use scarce shared resources and do not have external timing constraints. Consequently, the crew has no control over the schedule of the majority of their own tasks. As humans venture farther from earth for longer durations, it will become imperative that they have the ability to plan and schedule not only their own activities, but also the unattended activities of the systems, equipment, and robots on the journey with them. Significant software breakthroughs are required to enable the change in the operations concept. The crew does not have the time to build or modify the schedule by hand. They only need to issue a request to schedule a task and the system should automatically do the rest. Of course, the crew should not be required to build the complete schedule. Controllers on the ground should contribute the models and schedules where they have the better knowledge. The system must allow multiple simultaneous users, some on earth and some in space. The Mission Operations Laboratory at NASA's Marshall Space Flight Center has been researching and prototyping a modeling schema, scheduling engine, and system architecture that can enable the needed paradigm shift - it can make the crew autonomous. This schema and engine can be the core of a planning and scheduling system that would enable multiple planners, some on the earth and some in space, to build one integrated timeline. Its modeling schema can capture all the task requirements; its scheduling engine can build the schedule automatically; and its architecture can allow those (on earth and in space) with the best knowledge of the tasks to schedule them. This paper describes the enabling technology and proposes an operations concept for astronauts autonomously scheduling their activities and the activities around them.
Enabling New Operations Concepts for Lunar and Mars Exploration
NASA Technical Reports Server (NTRS)
Jaap, John; Maxwell, Theresa
2005-01-01
The planning and scheduling of human space activities is an expensive and time-consuming task that seldom provides the crew with the control, flexibility, or insight that they need. During the past thirty years, scheduling software has seen only incremental improvements; however, software limitations continue to prevent even evolutionary improvements in the operations concept that is used for human space missions. Space missions are planned on the ground long before they are executed in space, and the crew has little input or influence on the schedule. In recent years the crew has been presented with a job jar of activities that they can do whenever they have time, but the contents of the jar is limited to tasks that do not use scarce shared resources and do not have external timing constraints. Consequently, the crew has no control over the schedule of the majority of their own tasks. As humans venture farther from earth for longer durations, it will become imperative that they have the ability to plan and schedule not only their own activities, but also the unattended activities of the systems, equipment, and robots on the journey with them. Significant software breakthroughs are required to enable the change in the operations concept. The crew does not have the time to build or modify the schedule by hand. They only need to issue a request to schedule a task and the system should automatically do the rest. Of course, the crew should not be required to build the complete schedule. Controllers on the ground should contribute the models and schedules where they have the better knowledge. The system must allow multiple simultaneous users, some on earth and some in space. The Mission Operations Laboratory at NASA's Marshall Space flight Center has been researching and prototyping a modeling schema, scheduling engine, and system architecture that can enable the needed paradigm shift - it can make the crew autonomous. This schema and engine can be the core of a planning and scheduling system that would enable multiple planners, some on the earth and some in space, to build one integrated timeline. Its modeling schema can capture all the task requirements; its scheduling engine can build the schedule automatically, and its architecture can allow those (on earth and in space) with the best knowledge of the tasks to schedule them. This paper describes the enabling technology and proposes an operations concept for astronauts autonomously scheduling their activities and the activities around them.
Kumar, Shaji K; Laubach, Jacob P; Giove, Thomas J; Quick, Maureen; Neuwirth, Rachel; Yung, Godwin; Rajkumar, S Vincent; Richardson, Paul G
2017-09-01
Peripheral neuropathy (PN) is the most troublesome adverse event associated with the proteasome inhibitor bortezomib. Studies suggest an inflammatory aetiology for bortezomib-induced PN (BiPN) and it has been hypothesized that reducing inflammation with concomitant dexamethasone may reduce BiPN incidence and/or severity. We retrospectively analysed PN rates from 32 studies (2697 patients with previously untreated multiple myeloma) incorporating bortezomib and differing dexamethasone schedules: partnered dosing (days of and after bortezomib), weekly dosing, and other dosing schedules (e.g. days 1-4, 8-11). Pooled overall PN rates were 45·5%, 63·9%, and 47·5%, respectively, with 5·3%, 11·0%, and 9·6% grade ≥3. Adjusting for potential confounders (age, gender, presence of thalidomide, bortezomib treatment duration), PN rates in patients on partnered dosing schedules appeared lower than in patients on weekly or other dosing schedules. Analyses conducted using patient-level data suggest that cumulative dexamethasone dose, a potential confounding factor, is unlikely to have influenced the analyses. Findings were similar in a separate pooled analysis excluding data from regimens incorporating thalidomide, when pooled overall PN rates were 50·1%, 63·9%, and 48·3%, respectively, with 4·2%, 11·0%, and 8·6% grade ≥3. These findings suggest that partnered dexamethasone dosing may result in less severe BiPN compared with alternative dexamethasone dosing schedules. © 2017 John Wiley & Sons Ltd.
A Comparison of Techniques for Scheduling Fleets of Earth-Observing Satellites
NASA Technical Reports Server (NTRS)
Globus, Al; Crawford, James; Lohn, Jason; Pryor, Anna
2003-01-01
Earth observing satellite (EOS) scheduling is a complex real-world domain representative of a broad class of over-subscription scheduling problems. Over-subscription problems are those where requests for a facility exceed its capacity. These problems arise in a wide variety of NASA and terrestrial domains and are .XI important class of scheduling problems because such facilities often represent large capital investments. We have run experiments comparing multiple variants of the genetic algorithm, hill climbing, simulated annealing, squeaky wheel optimization and iterated sampling on two variants of a realistically-sized model of the EOS scheduling problem. These are implemented as permutation-based methods; methods that search in the space of priority orderings of observation requests and evaluate each permutation by using it to drive a greedy scheduler. Simulated annealing performs best and random mutation operators outperform our squeaky (more intelligent) operator. Furthermore, taking smaller steps towards the end of the search improves performance.
A distributed scheduling algorithm for heterogeneous real-time systems
NASA Technical Reports Server (NTRS)
Zeineldine, Osman; El-Toweissy, Mohamed; Mukkamala, Ravi
1991-01-01
Much of the previous work on load balancing and scheduling in distributed environments was concerned with homogeneous systems and homogeneous loads. Several of the results indicated that random policies are as effective as other more complex load allocation policies. The effects of heterogeneity on scheduling algorithms for hard real time systems is examined. A distributed scheduler specifically to handle heterogeneities in both nodes and node traffic is proposed. The performance of the algorithm is measured in terms of the percentage of jobs discarded. While a random task allocation is very sensitive to heterogeneities, the algorithm is shown to be robust to such non-uniformities in system components and load.
SLURM: Simple Linux Utility for Resource Management
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jette, M; Grondona, M
2002-12-19
Simple Linux Utility for Resource Management (SLURM) is an open source, fault-tolerant, and highly scalable cluster management and job scheduling system for Linux clusters of thousands of nodes. Components include machine status, partition management, job management, scheduling and stream copy modules. This paper presents an overview of the SLURM architecture and functionality.
SLURM: Simplex Linux Utility for Resource Management
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jette, M; Grondona, M
2003-04-22
Simple Linux Utility for Resource Management (SLURM) is an open source, fault-tolerant, and highly scalable cluster management and job scheduling system for Linux clusters of thousands of nodes. Components include machine status, partition management, job management, scheduling, and stream copy modules. This paper presents an overview of the SLURM architecture and functionality.
Prasanna Gowda
2016-01-01
Evapotranspiration (ET) is an essential component of the water balance and a major consumptive use of irrigation water and precipitation on cropland. Any attempt to improve water use efficiency must be based on reliable estimates of ET for irrigation scheduling purposes.
NASA Astrophysics Data System (ADS)
Iwamura, Koji; Kuwahara, Shinya; Tanimizu, Yoshitaka; Sugimura, Nobuhiro
Recently, new distributed architectures of manufacturing systems are proposed, aiming at realizing more flexible control structures of the manufacturing systems. Many researches have been carried out to deal with the distributed architectures for planning and control of the manufacturing systems. However, the human operators have not yet been discussed for the autonomous components of the distributed manufacturing systems. A real-time scheduling method is proposed, in this research, to select suitable combinations of the human operators, the resources and the jobs for the manufacturing processes. The proposed scheduling method consists of following three steps. In the first step, the human operators select their favorite manufacturing processes which they will carry out in the next time period, based on their preferences. In the second step, the machine tools and the jobs select suitable combinations for the next machining processes. In the third step, the automated guided vehicles and the jobs select suitable combinations for the next transportation processes. The second and third steps are carried out by using the utility value based method and the dispatching rule-based method proposed in the previous researches. Some case studies have been carried out to verify the effectiveness of the proposed method.
Multi-Objective Approach for Energy-Aware Workflow Scheduling in Cloud Computing Environments
Kadima, Hubert; Granado, Bertrand
2013-01-01
We address the problem of scheduling workflow applications on heterogeneous computing systems like cloud computing infrastructures. In general, the cloud workflow scheduling is a complex optimization problem which requires considering different criteria so as to meet a large number of QoS (Quality of Service) requirements. Traditional research in workflow scheduling mainly focuses on the optimization constrained by time or cost without paying attention to energy consumption. The main contribution of this study is to propose a new approach for multi-objective workflow scheduling in clouds, and present the hybrid PSO algorithm to optimize the scheduling performance. Our method is based on the Dynamic Voltage and Frequency Scaling (DVFS) technique to minimize energy consumption. This technique allows processors to operate in different voltage supply levels by sacrificing clock frequencies. This multiple voltage involves a compromise between the quality of schedules and energy. Simulation results on synthetic and real-world scientific applications highlight the robust performance of the proposed approach. PMID:24319361
Multi-objective approach for energy-aware workflow scheduling in cloud computing environments.
Yassa, Sonia; Chelouah, Rachid; Kadima, Hubert; Granado, Bertrand
2013-01-01
We address the problem of scheduling workflow applications on heterogeneous computing systems like cloud computing infrastructures. In general, the cloud workflow scheduling is a complex optimization problem which requires considering different criteria so as to meet a large number of QoS (Quality of Service) requirements. Traditional research in workflow scheduling mainly focuses on the optimization constrained by time or cost without paying attention to energy consumption. The main contribution of this study is to propose a new approach for multi-objective workflow scheduling in clouds, and present the hybrid PSO algorithm to optimize the scheduling performance. Our method is based on the Dynamic Voltage and Frequency Scaling (DVFS) technique to minimize energy consumption. This technique allows processors to operate in different voltage supply levels by sacrificing clock frequencies. This multiple voltage involves a compromise between the quality of schedules and energy. Simulation results on synthetic and real-world scientific applications highlight the robust performance of the proposed approach.
NASA Astrophysics Data System (ADS)
Hayward, Christopher C.; Chapman, Scott C.; Steidel, Charles C.; Golob, Anneya; Casey, Caitlin M.; Smith, Daniel J. B.; Zitrin, Adi; Blain, Andrew W.; Bremer, Malcolm N.; Chen, Chian-Chou; Coppin, Kristen E. K.; Farrah, Duncan; Ibar, Eduardo; Michałowski, Michał J.; Sawicki, Marcin; Scott, Douglas; van der Werf, Paul; Fazio, Giovanni G.; Geach, James E.; Gurwell, Mark; Petitpas, Glen; Wilner, David J.
2018-05-01
Interferometric observations have demonstrated that a significant fraction of single-dish submillimetre (submm) sources are blends of multiple submm galaxies (SMGs), but the nature of this multiplicity, i.e. whether the galaxies are physically associated or chance projections, has not been determined. We performed spectroscopy of 11 SMGs in six multicomponent submm sources, obtaining spectroscopic redshifts for nine of them. For an additional two component SMGs, we detected continuum emission but no obvious features. We supplement our observed sources with four single-dish submm sources from the literature. This sample allows us to statistically constrain the physical nature of single-dish submm source multiplicity for the first time. In three (3/7, { or} 43^{+39 }_{ -33} {per cent at 95 {per cent} confidence}) of the single-dish sources for which the nature of the blending is unambiguous, the components for which spectroscopic redshifts are available are physically associated, whereas 4/7 (57^{+33 }_{ -39} per cent) have at least one unassociated component. When components whose spectra exhibit continuum but no features and for which the photometric redshift is significantly different from the spectroscopic redshift of the other component are also considered, 6/9 (67^{+26 }_{ -37} per cent) of the single-dish sources are comprised of at least one unassociated component SMG. The nature of the multiplicity of one single-dish source is ambiguous. We conclude that physically associated systems and chance projections both contribute to the multicomponent single-dish submm source population. This result contradicts the conventional wisdom that bright submm sources are solely a result of merger-induced starbursts, as blending of unassociated galaxies is also important.
NASA Technical Reports Server (NTRS)
1980-01-01
The solar heating system installer guidelines are presented for each subsystem. This single family residential heating system is a solar-assisted, hydronic-to-warm-air system with solar-assisted domestic water heating. It is composed of the following major components: (1) liquid cooled flat plate collectors; (2) water storage tank; (3) passive solar-fired domestic water preheater; (4) electric hot water heater; (5) heat pump with electric backup; (6) solar hot water coil unit; (7) tube-and-shell heat exchanger, three pumps, and associated pipes and valving in an energy transport module; (8) control system; and (9) air-cooled heat purge unit. Information is provided on the operating procedures, controls, caution requirements, and routine and schedule maintenance in the form of written descriptions, schematics, detail drawings, pictures, and manufacturer's component data.
ERIC Educational Resources Information Center
Tomlin, Michelle; Reed, Phil
2012-01-01
The effects of fixed-time (FT) reinforcement schedules on the disruptive behavior of 4 students in special education classrooms were studied. Attention provided on FT schedules in the context of a multiple-baseline design across participants substantially decreased all students' challenging behavior. Disruptive behavior was maintained at levels…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-09
... licenses included in Auction 89 using the Commission's standard simultaneous multiple-round auction format... sequential bidding rounds. The initial bidding schedule will be announced in a public notice to be released.... For Auction 89, the Bureau proposes to employ a simultaneous stopping rule approach. A simultaneous...
Treatment for Acquired Apraxia of Speech: Examination of Treatment Intensity and Practice Schedule
ERIC Educational Resources Information Center
Wambaugh, Julie L.; Nessler, Christina; Cameron, Rosalea; Mauszycki, Shannon C.
2013-01-01
Purpose: The authors designed this investigation to extend the development of a treatment for acquired apraxia of speech (AOS)--sound production treatment (SPT)--by examining the effects of 2 treatment intensities and 2 schedules of practice. Method: The authors used a multiple baseline design across participants and behaviors with 4 speakers with…
NASA Astrophysics Data System (ADS)
Chen, Zhe; Parker, B. J.; Feng, D. D.; Fulton, R.
2004-10-01
In this paper, we compare various temporal analysis schemes applied to dynamic PET for improved quantification, image quality and temporal compression purposes. We compare an optimal sampling schedule (OSS) design, principal component analysis (PCA) applied in the image domain, and principal component analysis applied in the sinogram domain; for region-of-interest quantification, sinogram-domain PCA is combined with the Huesman algorithm to quantify from the sinograms directly without requiring reconstruction of all PCA channels. Using a simulated phantom FDG brain study and three clinical studies, we evaluate the fidelity of the compressed data for estimation of local cerebral metabolic rate of glucose by a four-compartment model. Our results show that using a noise-normalized PCA in the sinogram domain gives similar compression ratio and quantitative accuracy to OSS, but with substantially better precision. These results indicate that sinogram-domain PCA for dynamic PET can be a useful preprocessing stage for PET compression and quantification applications.
Multi-Axis Thrust Measurements of the EO-1 Pulsed Plasma Thruster
NASA Technical Reports Server (NTRS)
Arrington, Lynn A.; Haag, Thomas W.
1999-01-01
Pulsed plasma thrusters are low thrust propulsive devices which have a high specific impulse at low power. A pulsed plasma thruster is currently scheduled to fly as an experiment on NASA's Earth Observing-1 satellite mission. The pulsed plasma thruster will be used to replace one of the reaction wheels. As part of the qualification testing of the thruster it is necessary to determine the nominal thrust as a function of charge energy. These data will be used to determine control algorithms. Testing was first completed on a breadboard pulsed plasma thruster to determine nominal or primary axis thrust and associated propellant mass consumption as a function of energy and then later to determine if any significant off-axis thrust component existed. On conclusion that there was a significant off-axis thrust component with the bread-board in the direction of the anode electrode, the test matrix was expanded on the flight hardware to include thrust measurements along all three orthogonal axes. Similar off-axis components were found with the flight unit.
Sleep and respiration in microgravity
NASA Technical Reports Server (NTRS)
Prisk, G. K.
1998-01-01
Sleep studies conducted during the STS-90 Neurolab mission are explored. The relationship between sleep, melatonin, and circadian phase is reviewed. The study contained both sleep and awake components. The objectives of the sleep component were to test five hypotheses: that circadian rhythms of core body temperature and urinary melatonin are synchronized to required sleep-wake schedules, that spaceflight results in substantial disruption of sleep, that the pattern of chest and abdominal wall motion alters during the different sleep stages in microgravity, that arterial oxygen saturation is reduced during some stages of sleep in microgravity, and that pre-sleep administration of melatonin during microgravity results in improved sleep quality. The awake component tested three hypotheses: that ventilatory response to carbon dioxide is increased during exposure to microgravity and that this exacerbates sleep disruption, that ventilatory response to hypoxia is increased by exposure to microgravity, and that the improved sleep resulting from the pre-sleep administration of melatonin enhances next day cognition when compared to placebo.
Hackenberg, T D; Hineline, P N
1992-01-01
Pigeons chose between two schedules of food presentation, a fixed-interval schedule and a progressive-interval schedule that began at 0 s and increased by 20 s with each food delivery provided by that schedule. Choosing one schedule disabled the alternate schedule and stimuli until the requirements of the chosen schedule were satisfied, at which point both schedules were again made available. Fixed-interval duration remained constant within individual sessions but varied across conditions. Under reset conditions, completing the fixed-interval schedule not only produced food but also reset the progressive interval to its minimum. Blocks of sessions under the reset procedure were interspersed with sessions under a no-reset procedure, in which the progressive schedule value increased independent of fixed-interval choices. Median points of switching from the progressive to the fixed schedule varied systematically with fixed-interval value, and were consistently lower during reset than during no-reset conditions. Under the latter, each subject's choices of the progressive-interval schedule persisted beyond the point at which its requirements equaled those of the fixed-interval schedule at all but the highest fixed-interval value. Under the reset procedure, switching occurred at or prior to that equality point. These results qualitatively confirm molar analyses of schedule preference and some versions of optimality theory, but they are more adequately characterized by a model of schedule preference based on the cumulated values of multiple reinforcers, weighted in inverse proportion to the delay between the choice and each successive reinforcer. PMID:1548449
Distributed intelligent scheduling of FMS
NASA Astrophysics Data System (ADS)
Wu, Zuobao; Cheng, Yaodong; Pan, Xiaohong
1995-08-01
In this paper, a distributed scheduling approach of a flexible manufacturing system (FMS) is presented. A new class of Petri nets called networked time Petri nets (NTPN) for system modeling of networking environment is proposed. The distributed intelligent scheduling is implemented by three schedulers which combine NTPN models with expert system techniques. The simulation results are shown.
Reliability-based optimization of maintenance scheduling of mechanical components under fatigue
Beaurepaire, P.; Valdebenito, M.A.; Schuëller, G.I.; Jensen, H.A.
2012-01-01
This study presents the optimization of the maintenance scheduling of mechanical components under fatigue loading. The cracks of damaged structures may be detected during non-destructive inspection and subsequently repaired. Fatigue crack initiation and growth show inherent variability, and as well the outcome of inspection activities. The problem is addressed under the framework of reliability based optimization. The initiation and propagation of fatigue cracks are efficiently modeled using cohesive zone elements. The applicability of the method is demonstrated by a numerical example, which involves a plate with two holes subject to alternating stress. PMID:23564979
Improved Scheduling Mechanisms for Synchronous Information and Energy Transmission.
Qin, Danyang; Yang, Songxiang; Zhang, Yan; Ma, Jingya; Ding, Qun
2017-06-09
Wireless energy collecting technology can effectively reduce the network time overhead and prolong the wireless sensor network (WSN) lifetime. However, the traditional energy collecting technology cannot achieve the balance between ergodic channel capacity and average collected energy. In order to solve the problem of the network transmission efficiency and the limited energy of wireless devices, three improved scheduling mechanisms are proposed: improved signal noise ratio (SNR) scheduling mechanism (IS2M), improved N-SNR scheduling mechanism (INS2M) and an improved Equal Throughput scheduling mechanism (IETSM) for different channel conditions to improve the whole network performance. Meanwhile, the average collected energy of single users and the ergodic channel capacity of three scheduling mechanisms can be obtained through the order statistical theory in Rayleig, Ricean, Nakagami- m and Weibull fading channels. It is concluded that the proposed scheduling mechanisms can achieve better balance between energy collection and data transmission, so as to provide a new solution to realize synchronous information and energy transmission for WSNs.
Improved Scheduling Mechanisms for Synchronous Information and Energy Transmission
Qin, Danyang; Yang, Songxiang; Zhang, Yan; Ma, Jingya; Ding, Qun
2017-01-01
Wireless energy collecting technology can effectively reduce the network time overhead and prolong the wireless sensor network (WSN) lifetime. However, the traditional energy collecting technology cannot achieve the balance between ergodic channel capacity and average collected energy. In order to solve the problem of the network transmission efficiency and the limited energy of wireless devices, three improved scheduling mechanisms are proposed: improved signal noise ratio (SNR) scheduling mechanism (IS2M), improved N-SNR scheduling mechanism (INS2M) and an improved Equal Throughput scheduling mechanism (IETSM) for different channel conditions to improve the whole network performance. Meanwhile, the average collected energy of single users and the ergodic channel capacity of three scheduling mechanisms can be obtained through the order statistical theory in Rayleig, Ricean, Nakagami-m and Weibull fading channels. It is concluded that the proposed scheduling mechanisms can achieve better balance between energy collection and data transmission, so as to provide a new solution to realize synchronous information and energy transmission for WSNs. PMID:28598395
DOE Office of Scientific and Technical Information (OSTI.GOV)
Samaan, Nader A.; Milligan, Michael; Hunsaker, Matthew
This paper introduces a Production Cost Modeling (PCM) approach to evaluate the benefits of intra-hour scheduling between Balancing Authorities (BAs). The system operation is modeled in a three-stage sequential manner: day ahead (DA)-hour ahead (HA)-real time (RT). In addition to contingency reserve, each BA will need to carry out “up” and “down” load following and regulation reserve capacity requirements in the DA and HA time frames. In the real-time simulation, only contingency and regulation reserves are carried out as load following is deployed. To model current real-time operation with hourly schedules, a new constraint was introduced to force each BAmore » net exchange schedule deviation from HA schedules to be within NERC ACE limits. Case studies that investigate the benefits of moving from hourly exchange schedules between WECC BAs into 10-min exchange schedules under two different levels of wind and solar penetration (11% and 33%) are presented.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Samaan, Nader; Milligan, Michael; Hunsaker, Matt
This paper introduces a production cost modeling approach for evaluating the benefits of intra-hour scheduling among Balancing Authorities (BAs). System operation is modeled in a three-stage sequential manner: day ahead (DA)-hour ahead (HA) real time (RT). In addition to contingency reserve, each BA will need to carry out 'up' and 'down' load following and regulation reserve capacity requirements in the DA and HA time frames. In the RT simulation, only contingency and regulation reserves are carried out as load following is deployed. To model current RT operation with hourly schedules, a new constraint was introduced to force each BA netmore » exchange schedule deviation from HA schedules to be within North American Electric Reliability Corporation (NERC) area control error (ACE) limits. Case studies that investigate the benefits of moving from hourly exchange schedules between Western Electricity Coordinating Council (WECC) BAs into 10-minute exchange schedules under two different levels of wind and solar penetration (11% and 33%) are presented.« less
Development of the Perceived Multiple Role Stress Scale (PMRS).
Gigliotti, E
2001-01-01
Assessment of women's perception of multiple-role stress arising from occupancy of the maternal and student role is crucial if we are to engage in prevention and intervention strategies. Existing measures do not fully address the components of multiple role stress in this population: emotional role ambiguity, person-role and inter-role conflict. This article describes the development of the Perceived Multiple Role Stress Scale (PMRS) which was derived from Kahn, Wolfe, Quinn and Snoek's (1964) systems-based role theory. The 8-item, 3-factor PMRS measures multiple role stress in women who are both mothers and students. Review of the PMRS by role stress and women's roles experts supported content validity. Construct validity was supported in three phases over a five-year period. It is recommended that the three correlated factors be used as one eight-item scale. The internal consistency for the PMRS was .86.
Hughes, D A; Deegan, P B; Milligan, A; Wright, N; Butler, L H; Jacobs, A; Mehta, A B
2013-07-01
Anecdotal reports suggest that the currently approved dosing interval of agalsidase alfa (0.2 mg/kg/2 weeks) for Fabry disease treatment is too long. This randomised, double-blind, placebo-controlled, crossover study investigated three altered dosing intervals. 18 Fabry patients received three agalsidase alfa dosing schedules, each for four weeks (A: 0.2 mg/kg∗2 weeks, B: 0.1 mg/kg/week, C: 0.2 mg/kg/week). Health state, pain levels, sweat volume and latency and plasma and urinary globotriaosylceramide levels were recorded throughout the study. No significant differences were found among the schedules for the primary efficacy outcome of self-assessed health state, or for pain scores. A trend toward increased sweat volume on QSART testing, and reduced urine globotriaosylceramide concentration were seen with treatment schedule C. Agalsidase alfa was safe and well tolerated with all schedules. In conclusion, the primary analyses did not find weekly infusions of agalsidase alfa to be statistically better than the approved dosing schedule however the data indicates that further studies with more patients over a longer period are required to more accurately determine the optimum dose and schedule. Copyright © 2013 Elsevier Inc. All rights reserved.
The Updated Multiple Star Catalog
NASA Astrophysics Data System (ADS)
Tokovinin, Andrei
2018-03-01
The catalog of hierarchical stellar systems with three or more components is an update of the original 1997 version. For 2000 hierarchies, the new Multiple Star Catalog (MSC) provides distances, component masses and periods, and supplementary information (astrometry, photometry, identifiers, orbits, notes). The MSC content and format are explained, and its incompleteness and strong observational selection are stressed. Nevertheless, the MSC can be used for statistical studies and is a valuable source for planning observations of multiple stars. Rare classes of stellar hierarchies found in the MSC (with six or seven components, extremely eccentric orbits, planar and possibly resonant orbits, hosting planets) are briefly presented. High-order hierarchies have smaller velocity dispersion compared to triples and are often associated with moving groups. The paper concludes with an analysis of the ratio of periods and separations between inner and outer subsystems. In wide hierarchies, the ratio of semimajor axes, estimated statistically, is distributed between 3 and 300, with no evidence of dynamically unstable systems.
Kwon, Yong Hyun; Kwon, Jung Won; Lee, Myoung Hee
2015-01-01
[Purpose] The purpose of the current study was to compare the effectiveness of motor sequential learning according to two different types of practice schedules, distributed practice schedule (two 12-hour inter-trial intervals) and massed practice schedule (two 10-minute inter-trial intervals) using a serial reaction time (SRT) task. [Subjects and Methods] Thirty healthy subjects were recruited and then randomly and evenly assigned to either the distributed practice group or the massed practice group. All subjects performed three consecutive sessions of the SRT task following one of the two different types of practice schedules. Distributed practice was scheduled for two 12-hour inter-session intervals including sleeping time, whereas massed practice was administered for two 10-minute inter-session intervals. Response time (RT) and response accuracy (RA) were measured in at pre-test, mid-test, and post-test. [Results] For RT, univariate analysis demonstrated significant main effects in the within-group comparison of the three tests as well as the interaction effect of two groups × three tests, whereas the between-group comparison showed no significant effect. The results for RA showed no significant differences in neither the between-group comparison nor the interaction effect of two groups × three tests, whereas the within-group comparison of the three tests showed a significant main effect. [Conclusion] Distributed practice led to enhancement of motor skill acquisition at the first inter-session interval as well as at the second inter-interval the following day, compared to massed practice. Consequentially, the results of this study suggest that a distributed practice schedule can enhance the effectiveness of motor sequential learning in 1-day learning as well as for two days learning formats compared to massed practice. PMID:25931727
30 CFR 18.97 - Inspection of machines; minimum requirements.
Code of Federal Regulations, 2013 CFR
2013-07-01
... all electrical components for materials, workmanship, design, and construction; (2) Examination of all components of the machine which have been approved or certified under Bureau of Mines Schedule 2D, 2E, 2F, or...
30 CFR 18.97 - Inspection of machines; minimum requirements.
Code of Federal Regulations, 2012 CFR
2012-07-01
... all electrical components for materials, workmanship, design, and construction; (2) Examination of all components of the machine which have been approved or certified under Bureau of Mines Schedule 2D, 2E, 2F, or...
30 CFR 18.97 - Inspection of machines; minimum requirements.
Code of Federal Regulations, 2014 CFR
2014-07-01
... all electrical components for materials, workmanship, design, and construction; (2) Examination of all components of the machine which have been approved or certified under Bureau of Mines Schedule 2D, 2E, 2F, or...
Ulloa, Alvaro; Jingyu Liu; Vergara, Victor; Jiayu Chen; Calhoun, Vince; Pattichis, Marios
2014-01-01
In the biomedical field, current technology allows for the collection of multiple data modalities from the same subject. In consequence, there is an increasing interest for methods to analyze multi-modal data sets. Methods based on independent component analysis have proven to be effective in jointly analyzing multiple modalities, including brain imaging and genetic data. This paper describes a new algorithm, three-way parallel independent component analysis (3pICA), for jointly identifying genomic loci associated with brain function and structure. The proposed algorithm relies on the use of multi-objective optimization methods to identify correlations among the modalities and maximally independent sources within modality. We test the robustness of the proposed approach by varying the effect size, cross-modality correlation, noise level, and dimensionality of the data. Simulation results suggest that 3p-ICA is robust to data with SNR levels from 0 to 10 dB and effect-sizes from 0 to 3, while presenting its best performance with high cross-modality correlations, and more than one subject per 1,000 variables. In an experimental study with 112 human subjects, the method identified links between a genetic component (pointing to brain function and mental disorder associated genes, including PPP3CC, KCNQ5, and CYP7B1), a functional component related to signal decreases in the default mode network during the task, and a brain structure component indicating increases of gray matter in brain regions of the default mode region. Although such findings need further replication, the simulation and in-vivo results validate the three-way parallel ICA algorithm presented here as a useful tool in biomedical data decomposition applications.
NASA Instrument Cost/Schedule Model
NASA Technical Reports Server (NTRS)
Habib-Agahi, Hamid; Mrozinski, Joe; Fox, George
2011-01-01
NASA's Office of Independent Program and Cost Evaluation (IPCE) has established a number of initiatives to improve its cost and schedule estimating capabilities. 12One of these initiatives has resulted in the JPL developed NASA Instrument Cost Model. NICM is a cost and schedule estimator that contains: A system level cost estimation tool; a subsystem level cost estimation tool; a database of cost and technical parameters of over 140 previously flown remote sensing and in-situ instruments; a schedule estimator; a set of rules to estimate cost and schedule by life cycle phases (B/C/D); and a novel tool for developing joint probability distributions for cost and schedule risk (Joint Confidence Level (JCL)). This paper describes the development and use of NICM, including the data normalization processes, data mining methods (cluster analysis, principal components analysis, regression analysis and bootstrap cross validation), the estimating equations themselves and a demonstration of the NICM tool suite.
NASA Technical Reports Server (NTRS)
Kong, Edmund M.; Saenz-Otero, Alvar; Nolet, Simon; Berkovitz, Dustin S.; Miller, David W.; Sell, Steve W.
2004-01-01
The MIT-SSL SPHERES testbed provides a facility for the development of algorithms necessary for the success of Distributed Satellite Systems (DSS). The initial development contemplated formation flight and docking control algorithms; SPHERES now supports the study of metrology, control, autonomy, artificial intelligence, and communications algorithms and their effects on DSS projects. To support this wide range of topics, the SPHERES design contemplated the need to support multiple researchers, as echoed from both the hardware and software designs. The SPHERES operational plan further facilitates the development of algorithms by multiple researchers, while the operational locations incrementally increase the ability of the tests to operate in a representative environment. In this paper, an overview of the SPHERES testbed is first presented. The SPHERES testbed serves as a model of the design philosophies that allow for the various researches being carried out on such a facility. The implementation of these philosophies are further highlighted in the three different programs that are currently scheduled for testing onboard the International Space Station (ISS) and three that are proposed for a re-flight mission: Mass Property Identification, Autonomous Rendezvous and Docking, TPF Multiple Spacecraft Formation Flight in the first flight and Precision Optical Pointing, Tethered Formation Flight and Mars Orbit Sample Retrieval for the re-flight mission.
Stuckey, Bronwyn G A; Opie, Nicole; Cussons, Andrea J; Watts, Gerald F; Burke, Valerie
2014-08-01
Polycystic ovary syndrome (PCOS) is a prevalent condition with heterogeneity of clinical features and cardiovascular risk factors that implies multiple aetiological factors and possible outcomes. To reduce a set of correlated variables to a smaller number of uncorrelated and interpretable factors that may delineate subgroups within PCOS or suggest pathogenetic mechanisms. We used principal component analysis (PCA) to examine the endocrine and cardiometabolic variables associated with PCOS defined by the National Institutes of Health (NIH) criteria. Data were retrieved from the database of a single clinical endocrinologist. We included women with PCOS (N = 378) who were not taking the oral contraceptive pill or other sex hormones, lipid lowering medication, metformin or other medication that could influence the variables of interest. PCA was performed retaining those factors with eigenvalues of at least 1.0. Varimax rotation was used to produce interpretable factors. We identified three principal components. In component 1, the dominant variables were homeostatic model assessment (HOMA) index, body mass index (BMI), high density lipoprotein (HDL) cholesterol and sex hormone binding globulin (SHBG); in component 2, systolic blood pressure, low density lipoprotein (LDL) cholesterol and triglycerides; in component 3, total testosterone and LH/FSH ratio. These components explained 37%, 13% and 11% of the variance in the PCOS cohort respectively. Multiple correlated variables from patients with PCOS can be reduced to three uncorrelated components characterised by insulin resistance, dyslipidaemia/hypertension or hyperandrogenaemia. Clustering of risk factors is consistent with different pathogenetic pathways within PCOS and/or differing cardiometabolic outcomes. Copyright © 2014 Elsevier Inc. All rights reserved.
ERIC Educational Resources Information Center
Akin, Fatma Nur; Uzuntiryaki-Kondakci, Esen
2018-01-01
We examined the interactions among pedagogical content knowledge (PCK) components of novice and experienced chemistry teachers in teaching reaction rate and chemical equilibrium topics in this qualitative multiple-case design study. For this aim, three chemistry teachers who had different levels of teaching experience in chemistry teaching were…
Using Knowledge Base for Event-Driven Scheduling of Web Monitoring Systems
NASA Astrophysics Data System (ADS)
Kim, Yang Sok; Kang, Sung Won; Kang, Byeong Ho; Compton, Paul
Web monitoring systems report any changes to their target web pages by revisiting them frequently. As they operate under significant resource constraints, it is essential to minimize revisits while ensuring minimal delay and maximum coverage. Various statistical scheduling methods have been proposed to resolve this problem; however, they are static and cannot easily cope with events in the real world. This paper proposes a new scheduling method that manages unpredictable events. An MCRDR (Multiple Classification Ripple-Down Rules) document classification knowledge base was reused to detect events and to initiate a prompt web monitoring process independent of a static monitoring schedule. Our experiment demonstrates that the approach improves monitoring efficiency significantly.
Applying the Extended Parallel Process Model to workplace safety messages.
Basil, Michael; Basil, Debra; Deshpande, Sameer; Lavack, Anne M
2013-01-01
The extended parallel process model (EPPM) proposes fear appeals are most effective when they combine threat and efficacy. Three studies conducted in the workplace safety context examine the use of various EPPM factors and their effects, especially multiplicative effects. Study 1 was a content analysis examining the use of EPPM factors in actual workplace safety messages. Study 2 experimentally tested these messages with 212 construction trainees. Study 3 replicated this experiment with 1,802 men across four English-speaking countries-Australia, Canada, the United Kingdom, and the United States. The results of these three studies (1) demonstrate the inconsistent use of EPPM components in real-world work safety communications, (2) support the necessity of self-efficacy for the effective use of threat, (3) show a multiplicative effect where communication effectiveness is maximized when all model components are present (severity, susceptibility, and efficacy), and (4) validate these findings with gory appeals across four English-speaking countries.
2015-11-13
The Administrator of the Drug Enforcement Administration is issuing this final order extending the temporary schedule I status for three synthetic phenethylamines into the Controlled Substances Act pursuant to the temporary scheduling provisions of the Act. The substances are: 2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25I-NBOMe; 2C-I-NBOMe; 25I; Cimbi-5), 2-(4-chloro-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25C-NBOMe; 2C-C-NBOMe; 25C; Cimbi-82), and 2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (25B-NBOMe; 2C-B-NBOMe; 25B; Cimbi-36) [hereinafter 25I-NBOMe, 2C-NBOMe, and 25-NBOMe, respectively]. The initial temporary scheduling was based on a finding by the Deputy Administrator that the placement of these synthetic phenethylamines and their optical, positional, and geometric isomers, salts, and salts of isomers into schedule I of the Controlled Substances Act is necessary to avoid an imminent hazard to the public safety. The current final order temporarily placing 25I-NBOMe, 25C-NBOMe, and 25B-NBOMe in schedule I is due to expire on November 14, 2015. This final order will extend the temporary scheduling of 25I-NBOMe, 25C-NBOMe, and 25B-NBOMe for one year, or until the permanent scheduling action for these three substances is completed, whichever occurs first. As a result of this order, the full effect of the Controlled Substances Act and its implementing regulations, including criminal, civil and administrative penalties, sanctions, and regulatory controls of schedule I substances will be imposed on the manufacture, distribution, possession, importation, and exportation of these synthetic phenethylamines.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Castellana, Vito G.; Tumeo, Antonino; Ferrandi, Fabrizio
Emerging applications such as data mining, bioinformatics, knowledge discovery, social network analysis are irregular. They use data structures based on pointers or linked lists, such as graphs, unbalanced trees or unstructures grids, which generates unpredictable memory accesses. These data structures usually are large, but difficult to partition. These applications mostly are memory bandwidth bounded and have high synchronization intensity. However, they also have large amounts of inherent dynamic parallelism, because they potentially perform a task for each one of the element they are exploring. Several efforts are looking at accelerating these applications on hybrid architectures, which integrate general purpose processorsmore » with reconfigurable devices. Some solutions, which demonstrated significant speedups, include custom-hand tuned accelerators or even full processor architectures on the reconfigurable logic. In this paper we present an approach for the automatic synthesis of accelerators from C, targeted at irregular applications. In contrast to typical High Level Synthesis paradigms, which construct a centralized Finite State Machine, our approach generates dynamically scheduled hardware components. While parallelism exploitation in typical HLS-generated accelerators is usually bound within a single execution flow, our solution allows concurrently running multiple execution flow, thus also exploiting the coarser grain task parallelism of irregular applications. Our approach supports multiple, multi-ported and distributed memories, and atomic memory operations. Its main objective is parallelizing as many memory operations as possible, independently from their execution time, to maximize the memory bandwidth utilization. This significantly differs from current HLS flows, which usually consider a single memory port and require precise scheduling of memory operations. A key innovation of our approach is the generation of a memory interface controller, which dynamically maps concurrent memory accesses to multiple ports. We present a case study on a typical irregular kernel, Graph Breadth First search (BFS), exploring different tradeoffs in terms of parallelism and number of memories.« less
RSM 1.0 user's guide: A resupply scheduler using integer optimization
NASA Technical Reports Server (NTRS)
Viterna, Larry A.; Green, Robert D.; Reed, David M.
1991-01-01
The Resupply Scheduling Model (RSM) is a PC based, fully menu-driven computer program. It uses integer programming techniques to determine an optimum schedule to replace components on or before a fixed replacement period, subject to user defined constraints such as transportation mass and volume limits or available repair crew time. Principal input for RSJ includes properties such as mass and volume and an assembly sequence. Resource constraints are entered for each period corresponding to the component properties. Though written to analyze the electrical power system on the Space Station Freedom, RSM is quite general and can be used to model the resupply of almost any system subject to user defined resource constraints. Presented here is a step by step procedure for preparing the input, performing the analysis, and interpreting the results. Instructions for installing the program and information on the algorithms are given.
NASA Astrophysics Data System (ADS)
Fulton, A.; Snyder, R.; Hillyer, C.; English, M.; Sanden, B.; Munk, D.
2012-04-01
Enhancing Adoption of Irrigation Scheduling to Sustain the Viability of Fruit and Nut Crops in California Allan Fulton, Richard Snyder, Charles Hillyer, Marshall English, Blake Sanden, and Dan Munk Adoption of scientific methods to decide when to irrigate and how much water to apply to a crop has increased over the last three decades in California. In 1988, less than 4.3 percent of US farmers employed some type of science-based technique to assist in making irrigation scheduling decisions (USDA, 1995). An ongoing survey in California, representing an industry irrigating nearly 0.4 million planted almond hectares, indicates adoption rates ranging from 38 to 55 percent of either crop evapotranspiration (ETc), soil moisture monitoring, plant water status, or some combination of these irrigation scheduling techniques to assist with making irrigation management decisions (California Almond Board, 2011). High capital investment to establish fruit and nut crops, sensitivity to over and under-irrigation on crop performance and longevity, and increasing costs and competition for water have all contributed to increased adoption of scientific irrigation scheduling methods. These trends in adoption are encouraging and more opportunities exist to develop improved irrigation scheduling tools, especially computer decision-making models. In 2009 and 2010, an "On-line Irrigation Scheduling Advisory Service" (OISO, 2012), also referred to as Online Irrigation Management (IMO), was used and evaluated in commercial walnut, almond, and French prune orchards in the northern Sacramento Valley of California. This specific model has many features described as the "Next Generation of Irrigation Schedulers" (Hillyer, 2010). While conventional irrigation management involves simply irrigating as needed to avoid crop stress, this IMO is designed to control crop stress, which requires: (i) precise control of crop water availability (rather than controlling applied water); (ii) quantifying crop stress in order to manage it in heterogeneous fields; and (iii) predicting crop responses to water stress. The capacities of this IMO include: 1. Modeling of the disposition of applied water in spatially variable fields; 2. Conjunctive scheduling for multiple fields, rather than scheduling each field independently; 3. Long range forecasting of crop water requirements to better utilize limited water or limited delivery system capacity: and 4. Explicit modeling of the uncertainties of water use and crop yield. This was one of the first efforts to employ a "Next Generation" type computer irrigation scheduling advisory model or IMO in orchard crops. This paper discusses experiences with introducing this model to fruit and nut growers of various size and scale in the northern Sacramento Valley of California and the accuracy of its forecasts of irrigation needs in fruit and nut crops. Strengths and opportunities to forge ahead in the development of a "Next Generation" irrigation scheduler were identified from this on-farm evaluation.
2003-05-15
KENNEDY SPACE CENTER, FLA. - In the Payload Hazardous Servicing Facility, workers lower the backshell with the Mars Exploration Rover 1 (MER-1) onto the heat shield. The two components form the aeroshell that will protect the rover on its journey to Mars. NASA's twin Mars Exploration Rovers are designed to study the history of water on Mars. These robotic geologists are equipped with a robotic arm, a drilling tool, three spectrometers, and four pairs of cameras that allow them to have a human-like, 3D view of the terrain. Each rover could travel as far as 100 meters in one day to act as Mars scientists' eyes and hands, exploring an environment where humans can't yet go. MER-1 is scheduled to launch June 25 as MER-B aboard a Delta II rocket from Cape Canaveral Air Force Station.
Gene differentiation among ten endogamous groups of West Bengal, India.
Chakraborty, R; Walter, H; Mukherjee, B N; Malhotra, K C; Sauber, P; Banerjee, S; Roy, M
1986-11-01
Ten endogamous populations of West Bengal, India have been surveyed for genetic variation in 12 systems. These populations encompass all social ranks in the caste hierarchy and cover almost the entire geographic area of the state. Gene diversity analysis suggests that these groups exhibit significant allele frequency variation at all but three loci. The overall genetic difference is not, however, in accord with the classification based on caste. Two low-ranking scheduled caste groups are, in fact, in close proximity with the high-caste ones, suggesting evidence of past generations of gene flow among them. Three different clusters of groups emerge from the present data, providing support for the anthropologic assertion that in Bengal Proto-Australoid, Caucasoid, and Mongoloid racial elements generally coexist. However, these three components are not uniformly present in all groups. Geographic separation of the groups is a strong determinant of the gene differentiation that exists among these populations.
2007-10-01
KENNEDY SPACE CENTER, FLA. -- In the Space Station Processing Facility at NASA's Kennedy Space Center, the starboard arm of the Special Purpose Dexterous Manipulator, known as Dextre, is moved toward the base, in the background. The arm will be installed on the base. Dextre is a sophisticated dual-armed robot, which is part of Canada's contribution to the International Space Station (ISS). Along with Canadarm2, whose technical name is the Space Station Remote Manipulator System, and a moveable work platform called the Mobile Base System, these three elements form a robotic system called the Mobile Servicing System, or MSS. The three components have been designed to work together or independently. Dextre is part of the payload scheduled on mission STS-123, targeted to launch Feb. 14. Photo credit: NASA/George Shelton
2007-10-01
KENNEDY SPACE CENTER, FLA. -- In the Space Station Processing Facility at NASA's Kennedy Space Center, technicians aid with the lowering of the starboard arm of the Special Purpose Dexterous Manipulator, known as Dextre, toward the base. The arm will be installed on the base. Dextre is a sophisticated dual-armed robot, which is part of Canada's contribution to the International Space Station (ISS). Along with Canadarm2, whose technical name is the Space Station Remote Manipulator System, and a moveable work platform called the Mobile Base System, these three elements form a robotic system called the Mobile Servicing System, or MSS. The three components have been designed to work together or independently. Dextre is part of the payload scheduled on mission STS-123, targeted to launch Feb. 14. Photo credit: NASA/George Shelton
2007-10-01
KENNEDY SPACE CENTER, FLA. -- In the Space Station Processing Facility at NASA's Kennedy Space Center, technicians adjust the cables of an overhead crane on the starboard arm of the Special Purpose Dexterous Manipulator, known as Dextre. The arm will be moved to and installed on the base. Dextre is a sophisticated dual-armed robot, which is part of Canada's contribution to the International Space Station ISS. Along with Canadarm2, whose technical name is the Space Station Remote Manipulator System, and a moveable work platform called the Mobile Base System, these three elements form a robotic system called the Mobile Servicing System, or MSS. The three components have been designed to work together or independently. Dextre is part of the payload scheduled on mission STS-123, targeted to launch Feb. 14. Photo credit: NASA/George Shelton
2007-10-01
KENNEDY SPACE CENTER, FLA. -- In the Space Station Processing Facility at NASA's Kennedy Space Center, technicians begin raising the starboard arm of the Special Purpose Dexterous Manipulator, known as Dextre, for its move across the facility. The arm will be installed on the base. Dextre is a sophisticated dual-armed robot, which is part of Canada's contribution to the International Space Station ISS. Along with Canadarm2, whose technical name is the Space Station Remote Manipulator System, and a moveable work platform called the Mobile Base System, these three elements form a robotic system called the Mobile Servicing System, or MSS. The three components have been designed to work together or independently. Dextre is part of the payload scheduled on mission STS-123, targeted to launch Feb. 14. Photo credit: NASA/George Shelton
A Hybrid Task Graph Scheduler for High Performance Image Processing Workflows.
Blattner, Timothy; Keyrouz, Walid; Bhattacharyya, Shuvra S; Halem, Milton; Brady, Mary
2017-12-01
Designing applications for scalability is key to improving their performance in hybrid and cluster computing. Scheduling code to utilize parallelism is difficult, particularly when dealing with data dependencies, memory management, data motion, and processor occupancy. The Hybrid Task Graph Scheduler (HTGS) improves programmer productivity when implementing hybrid workflows for multi-core and multi-GPU systems. The Hybrid Task Graph Scheduler (HTGS) is an abstract execution model, framework, and API that increases programmer productivity when implementing hybrid workflows for such systems. HTGS manages dependencies between tasks, represents CPU and GPU memories independently, overlaps computations with disk I/O and memory transfers, keeps multiple GPUs occupied, and uses all available compute resources. Through these abstractions, data motion and memory are explicit; this makes data locality decisions more accessible. To demonstrate the HTGS application program interface (API), we present implementations of two example algorithms: (1) a matrix multiplication that shows how easily task graphs can be used; and (2) a hybrid implementation of microscopy image stitching that reduces code size by ≈ 43% compared to a manually coded hybrid workflow implementation and showcases the minimal overhead of task graphs in HTGS. Both of the HTGS-based implementations show good performance. In image stitching the HTGS implementation achieves similar performance to the hybrid workflow implementation. Matrix multiplication with HTGS achieves 1.3× and 1.8× speedup over the multi-threaded OpenBLAS library for 16k × 16k and 32k × 32k size matrices, respectively.
ACARA - AVAILABILITY, COST AND RESOURCE ALLOCATION
NASA Technical Reports Server (NTRS)
Viterna, L. A.
1994-01-01
ACARA is a program for analyzing availability, lifecycle cost, and resource scheduling. It uses a statistical Monte Carlo method to simulate a system's capacity states as well as component failure and repair. Component failures are modelled using a combination of exponential and Weibull probability distributions. ACARA schedules component replacement to achieve optimum system performance. The scheduling will comply with any constraints on component production, resupply vehicle capacity, on-site spares, or crew manpower and equipment. ACARA is capable of many types of analyses and trade studies because of its integrated approach. It characterizes the system performance in terms of both state availability and equivalent availability (a weighted average of state availability). It can determine the probability of exceeding a capacity state to assess reliability and loss of load probability. It can also evaluate the effect of resource constraints on system availability and lifecycle cost. ACARA interprets the results of a simulation and displays tables and charts for: (1) performance, i.e., availability and reliability of capacity states, (2) frequency of failure and repair, (3) lifecycle cost, including hardware, transportation, and maintenance, and (4) usage of available resources, including mass, volume, and maintenance man-hours. ACARA incorporates a user-friendly, menu-driven interface with full screen data entry. It provides a file management system to store and retrieve input and output datasets for system simulation scenarios. ACARA is written in APL2 using the APL2 interpreter for IBM PC compatible systems running MS-DOS. Hardware requirements for the APL2 system include 640K of RAM, 2Mb of extended memory, and an 80386 or 80486 processor with an 80x87 math co-processor. A dot matrix printer is required if the user wishes to print a graph from a results table. A sample MS-DOS executable is provided on the distribution medium. The executable contains licensed material from the APL2 for the IBM PC product which is program property of IBM; Copyright IBM Corporation 1988 - All rights reserved. It is distributed with IBM's permission. The standard distribution medium for this program is a set of three 5.25 inch 360K MS-DOS format diskettes. The contents of the diskettes are compressed using the PKWARE archiving tools. The utility to unarchive the files, PKUNZIP.EXE, is included. ACARA was developed in 1992.
NASA Technical Reports Server (NTRS)
Clement, Bradley; Johnston, Mark; Wax, Allan; Chouinard, Caroline
2008-01-01
The DSN (Deep Space Network) Scheduling Engine targets all space missions that use DSN services. It allows clients to issue scheduling, conflict identification, conflict resolution, and status requests in XML over a Java Message Service interface. The scheduling requests may include new requirements that represent a set of tracks to be scheduled under some constraints. This program uses a heuristic local search to schedule a variety of schedule requirements, and is being infused into the Service Scheduling Assembly, a mixed-initiative scheduling application. The engine resolves conflicting schedules of resource allocation according to a range of existing and possible requirement specifications, including optional antennas; start of track and track duration ranges; periodic tracks; locks on track start, duration, and allocated antenna; MSPA (multiple spacecraft per aperture); arraying/VLBI (very long baseline interferometry)/delta DOR (differential one-way ranging); continuous tracks; segmented tracks; gap-to-track ratio; and override or block-out of requirements. The scheduling models now include conflict identification for SOA(start of activity), BOT (beginning of track), RFI (radio frequency interference), and equipment constraints. This software will search through all possible allocations while providing a best-effort solution at any time. The engine reschedules to accommodate individual emergency tracks in 0.2 second, and emergency antenna downtime in 0.2 second. The software handles doubling of one mission's track requests over one week (to 42 total) in 2.7 seconds. Further tests will be performed in the context of actual schedules.
Shiftwork Scheduling for the 1990s.
ERIC Educational Resources Information Center
Coleman, Richard M.
1989-01-01
The author discusses the problems of scheduling shift work, touching on such topics as employee desires, health requirements, and business needs. He presents a method for developing shift schedules that addresses these three areas. Implementation hints are also provided. (CH)
Treatment of giant intradural (perimedullary) arteriovenous fistulas.
Halbach, V V; Higashida, R T; Dowd, C F; Fraser, K W; Edwards, M S; Barnwell, S L
1993-12-01
Ten patients with giant intradural spinal arteriovenous fistulas (perimedullary Types II and III) were treated with embolization alone (three patients) or in combination with surgery (seven patients). Their ages at the time of treatment ranged from 2 to 40 years, with a mean of 19.5 years. The indications for treatment included progressive myelopathy in five patients, spinal subarachnoid hemorrhage in four, and acute paraplegia in one. Associated conditions included Rendu-Osler-Weber syndrome in two patients, and Cobb's syndrome in two patients. In one patient, the cause of the fistula may have been related to epidural anesthesia traumatizing a low tethered cord. Angiographically, the fistulas were subclassified in three groups: a single-hole fistula supplied by a single feeding medullary artery (three patients); a single-hole fistula supplied by multiple medullary arteries (three patients); and multiple separate fistulas supplied by multiple medullary arteries (four patients). Eight patients were classified as perimedullary Type III and two as perimedullary Type II. Embolic agents were delivered from transarterial routes in 14 procedures and transvenous routes in 2 procedures. A total of 16 embolizations and 8 operations were performed in 10 patients. Seven patients were cured of their fistula (as demonstrated by angiography), two patients had 5% residual filling and are scheduled for future therapy. One refused a follow-up angiographic examination. Complications related to embolization included rupture of the anterior spinal artery by a detachable balloon, resulting in transient worsening of paraplegia with recovery to baseline. Transient worsening of symptoms after surgery was common, but all patients returned to baseline or better. Dramatic improvement was observed in four patients.(ABSTRACT TRUNCATED AT 250 WORDS)
NASA Astrophysics Data System (ADS)
Shimura, Tsutomu; Takeda, Yuki; Endo, Masao; Umegaki, Shinsuke; Fujimura, Ryushi
2016-09-01
Recently new photopolymers that does not require scheduled exposure in the multiple page writing for the holographic memory was introduced. Its sensitivity does not decrease throughout the multiple page writing process. We will explain why this photopolymer has such a property with our reaction model. The key is the existence of the molecules which make seeds of the polymers. At the first exposure process to record the page data, seeds are produced corresponding to the light intensity distribution. Then after writing the information of all multiplexed pages, the seeds are growing to be polymers under the spatially uniform light illumination.
Bouchard-Cannon, Pascale; Cheng, Hai-Ying M.
2013-01-01
Restricted feeding (RF) schedules are potent zeitgebers capable of entraining metabolic and hormonal rhythms in peripheral oscillators in anticipation of food. Behaviorally, this manifests in the form of food anticipatory activity (FAA) in the hours preceding food availability. Circadian rhythms of FAA are thought to be controlled by a food-entrainable oscillator (FEO) outside of the suprachiasmatic nucleus (SCN), the central circadian pacemaker in mammals. Although evidence suggests that the FEO and the SCN are capable of interacting functionally under RF conditions, the genetic basis of these interactions remains to be defined. In this study, using dexras1-deficient (dexras1−/−) mice, the authors examined whether Dexras1, a modulator of multiple inputs to the SCN, plays a role in regulating the effects of RF on activity rhythms and gene expression in the SCN. Daytime RF under 12L:12D or constant darkness (DD) resulted in potentiated (but less stable) FAA expression in dexras1−/− mice compared with wild-type (WT) controls. Under these conditions, the magnitude and phase of the SCN-driven activity component were greatly perturbed in the mutants. Restoration to ad libitum (AL) feeding revealed a stable phase displacement of the SCN-driven activity component of dexras1−/− mice by ~2 h in advance of the expected time. RF in the late night/early morning induced a long-lasting increase in the period of the SCN-driven activity component in the mutants but not the WT. At the molecular level, daytime RF advanced the rhythm of PER1, PER2, and pERK expression in the mutant SCN without having any effect in the WT. Collectively, these results indicate that the absence of Dexras1 sensitizes the SCN to perturbations resulting from restricted feeding. PMID:22928915
Power-based Shift Schedule for Pure Electric Vehicle with a Two-speed Automatic Transmission
NASA Astrophysics Data System (ADS)
Wang, Jiaqi; Liu, Yanfang; Liu, Qiang; Xu, Xiangyang
2016-11-01
This paper introduces a comprehensive shift schedule for a two-speed automatic transmission of pure electric vehicle. Considering about driving ability and efficiency performance of electric vehicles, the power-based shift schedule is proposed with three principles. This comprehensive shift schedule regards the vehicle current speed and motor load power as input parameters to satisfy the vehicle driving power demand with lowest energy consumption. A simulation model has been established to verify the dynamic and economic performance of comprehensive shift schedule. Compared with traditional dynamic and economic shift schedules, simulation results indicate that the power-based shift schedule is superior to traditional shift schedules.
ERIC Educational Resources Information Center
Stambaugh, Laura A.; Demorest, Steven M.
2010-01-01
The effects of three practice schedules on beginning instrumental achievement were explored. A total of 19 seventh-grade clarinet and saxophone students completed one 18-minute practice session using either a blocked schedule causing a low level of cognitive (contextual) interference, a hybrid schedule causing a moderate level of interference, or…
Close, Ryan M; Pearson, Catherine; Cohn, Jennifer
2016-09-07
Complex humanitarian emergencies affect 40-60 million people annually and are a growing public health concern worldwide. Despite efforts to provide medical and public health services to populations affected by complex emergencies, significant morbidity and mortality persist. Measles is a major communicable disease threat, but through vaccination of broader target age groups beyond the traditional immunization schedule, measles-related mortality has been significantly reduced during crises. Yet, a limited number of vaccine-preventable diseases continue to contribute disproportionately to morbidity and mortality in complex emergencies. The literature suggests that Streptococcus pneumoniae, Rotavirus, and Haemophilus influenzae type-b should be key targets for vaccination programs. Because of the significant contribution of these three pathogens to complex humanitarian emergencies in low and middle-income countries regardless of disaster type, geography, or population, their vaccines should be considered essential components of the standard emergency response effort. We discuss the barriers to vaccine distribution and provide evidence for strategies to improve distribution, including expanded target age-range and reduced dose schedules. Our review includes specific recommendations for the expanded use of these three vaccines in complex emergencies in low and middle-income countries as a way to guide future policy discussions. Copyright © 2016 Elsevier Ltd. All rights reserved.
Mozumdar, Biswita C; Hornsby, Douglas Neal; Gogate, Adheet S; Intriere, Lisa A; Hanson, Richard; McGreal, Karen; Kelly, Pauline; Ros, Pablo
2003-08-01
To study end-user attitudes and preferences with respect to radiology scheduling systems and to assess implications for retention and extension of the referral base. A study of the institution's historical data indicated reduced satisfaction with the process of patient scheduling in recent years. Sixty physicians who referred patients to a single, large academic radiology department received the survey. The survey was designed to identify (A) the preferred vehicle for patient scheduling (on-line versus telephone scheduling) and (B) whether ease of scheduling was a factor in physicians referring patients to other providers. Referring physicians were asked to forward the survey to any appropriate office staff member in case the latter scheduled appointments for patients. Users were asked to provide comments and suggestions for improvement. The statistical method used was the analysis of proportions. Thirty-three responses were received, corresponding to a return rate of 55%. Twenty-six of the 33 respondents (78.8%, P < .01) stated they were willing to try an online scheduling system; 16 of which tried the system. Twelve of the 16 (75%, P < .05) preferred the on-line application to the telephone system, stating logistical simplification as the primary reason for preference. Three (18.75%) did not consider online scheduling to be more convenient than traditional telephone scheduling. One respondent did not indicate any preference. Eleven of 33 users (33.33%, P < .001) stated that they would change radiology service providers if expectations of scheduling ease are not met. On-line scheduling applications are becoming the preferred scheduling vehicle. Augmenting their capabilities and availability can simplify the scheduling process, improve referring physician satisfaction, and provide a competitive advantage. Referrers are willing to change providers if scheduling expectations are not met.
Liu, Ying; Uboh, Cornelius E; Soma, Lawrence R; Li, Xiaoqing; Guan, Fuyu; You, Youwen; Chen, Jin-Wen
2011-09-01
Multiple drug target analysis (MDTA) used in doping control is more efficient than single drug target analysis (SDTA). The number of drugs with the potential for abuse is so extensive that full coverage is not possible with SDTA. To address this problem, a liquid chromatography tandem mass spectrometric method was developed for simultaneous analysis of 302 drugs using a scheduled multiple reaction monitoring (s-MRM) algorithm. With a known retention time of an analyte, the s-MRM algorithm monitors each MRM transition only around its expected retention time. Analytes were recovered from plasma by liquid-liquid extraction. Information-dependent acquisition (IDA) functionality was used to combine s-MRM with enhanced product ion (EPI) scans within the same chromatographic analysis. An EPI spectrum library was also generated for rapid identification of analytes. Analysis time for the 302 drugs was 7 min. Scheduled MRM improved the quality of the chromatograms, signal response, reproducibility, and enhanced signal-to-noise ratio (S/N), resulting in more data points. Reduction in total cycle time from 2.4 s in conventional MRM (c-MRM) to 1 s in s-MRM allowed completion of the EPI scan at the same time. The speed for screening and identification of multiple drugs in equine plasma for doping control analysis was greatly improved by this method.
Galgani, Ilaria; Bunge, Eveline M; Hendriks, Lisa; Schludermann, Christopher; Marano, Cinzia; De Moerlooze, Laurence
2017-09-01
Tick-borne encephalitis (TBE), which is endemic across large regions of Europe and Asia, is most effectively prevented through vaccination. Three-dose primary TBE vaccination schedules are either rapid (0,7,21-days) or conventional (0,28-84-days, 9-12-months). The second dose can also be administered at 14 days for faster priming and sero-protection). Areas covered: We used a three-step selection process to identify 21 publications comparing the immunogenicity and/or safety of different schedules. Expert commentary: Priming with two or three TBE vaccine doses was highly immunogenic. After conventional priming (0-28 days), 95% adults and ≥95% children had neutralization test (NT) titers ≥10 at 14 days post-dose-2 compared with 92% adults and 99% children at 21 days post-dose-3 (rapid schedule). Most subjects retained NT titers ≥10 at day 300. A single booster dose induced a strong immune response in all subjects irrespective of primary vaccination schedule or elapsed time since priming. GMT peaked at 42 days post-dose-1 (i.e., 21 days post-dose 3 [rapid-schedule], or 14-28 days post-dose-2 [conventional-schedule]), and declined thereafter. Adverse events were generally rare and declined with increasing doses. In the absence of data to recommend one particular schedule, the regimen choice will remain at the physician's discretion, based on patient constraints and availability.
Computer-aided resource planning and scheduling for radiological services
NASA Astrophysics Data System (ADS)
Garcia, Hong-Mei C.; Yun, David Y.; Ge, Yiqun; Khan, Javed I.
1996-05-01
There exists tremendous opportunity in hospital-wide resource optimization based on system integration. This paper defines the resource planning and scheduling requirements integral to PACS, RIS and HIS integration. An multi-site case study is conducted to define the requirements. A well-tested planning and scheduling methodology, called Constrained Resource Planning model, has been applied to the chosen problem of radiological service optimization. This investigation focuses on resource optimization issues for minimizing the turnaround time to increase clinical efficiency and customer satisfaction, particularly in cases where the scheduling of multiple exams are required for a patient. How best to combine the information system efficiency and human intelligence in improving radiological services is described. Finally, an architecture for interfacing a computer-aided resource planning and scheduling tool with the existing PACS, HIS and RIS implementation is presented.
LH2 Tank Composite Coverplate Development and Flight Qualification for the X-33
NASA Technical Reports Server (NTRS)
Wright, Richard J.; Roule, Gerard M.
2000-01-01
In this paper, the development history for the first cryogenic pressurized fuel tank coverplates is presented along with a synopsis of the development strategy and technologies which led to success on this program. Coverplates are the large access panels used to access launch vehicle fuel tanks. These structures incorporate all of the requirements for a pressure vessel as well as the added requirement to mount all of the miscellaneous access points required for a fuel management system. The first composite coverplates to meet the requirements for flight qualification were developed on the X-33 program. The X-33 composite coverplates went from an open requirement to successful finished flight hardware with multiple unique configurations, complete with verification testing, in less than eighteen months. Besides the rapid development schedule, these components introduced several new technologies previously unseen in cryogenic composites including solutions to cryogenic shrinkage, self-supporting sealing surfaces, and highly loaded composite bosses with precision sealing interfaces. These components were proven to seal liquid hydrogen at cryogenic temperatures under maximum loading and pressure conditions.
NASA Astrophysics Data System (ADS)
Sembiring, N.; Panjaitan, N.; Saragih, A. F.
2018-02-01
PT. XYZ is a manufacturing company that produces fresh fruit bunches (FFB) to Crude Palm Oil (CPO) and Palm Kernel Oil (PKO). PT. XYZ consists of six work stations: receipt station, sterilizing station, thressing station, pressing station, clarification station, and kernelery station. So far, the company is still implementing corrective maintenance maintenance system for production machines where the machine repair is done after damage occurs. Problems at PT. XYZ is the absence of scheduling engine maintenance in a planned manner resulting in the engine often damaged which can disrupt the smooth production. Another factor that is the problem in this research is the kernel station environment that becomes less convenient for operators such as there are machines and equipment not used in the production area, slippery, muddy, scattered fibers, incomplete use of PPE, and lack of employee discipline. The most commonly damaged machine is in the seed processing station (kernel station) which is cake breaker conveyor machine. The solution of this problem is to propose a schedule plan for maintenance of the machine by using the method of reliability centered maintenance and also the application of 5S. The result of the application of Reliability Centered maintenance method is obtained four components that must be treated scheduled (time directed), namely: for bearing component is 37 days, gearbox component is 97 days, CBC pen component is 35 days and conveyor pedal component is 32 days While after identification the application of 5S obtained the proposed corporate environmental improvement measures in accordance with the principles of 5S where unused goods will be moved from the production area, grouping goods based on their use, determining the procedure of cleaning the production area, conducting inspection in the use of PPE, and making 5S slogans.
Optimization of an Aeroservoelastic Wing with Distributed Multiple Control Surfaces
NASA Technical Reports Server (NTRS)
Stanford, Bret K.
2015-01-01
This paper considers the aeroelastic optimization of a subsonic transport wingbox under a variety of static and dynamic aeroelastic constraints. Three types of design variables are utilized: structural variables (skin thickness, stiffener details), the quasi-steady deflection scheduling of a series of control surfaces distributed along the trailing edge for maneuver load alleviation and trim attainment, and the design details of an LQR controller, which commands oscillatory hinge moments into those same control surfaces. Optimization problems are solved where a closed loop flutter constraint is forced to satisfy the required flight margin, and mass reduction benefits are realized by relaxing the open loop flutter requirements.