TRANSPORT BY MERIDIONAL CIRCULATIONS IN SOLAR-TYPE STARS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wood, T. S.; Brummell, N. H., E-mail: tsw25@soe.ucsc.edu

2012-08-20

Transport by meridional flows has significant consequences for stellar evolution, but is difficult to capture in global-scale numerical simulations because of the wide range of timescales involved. Stellar evolution models therefore usually adopt parameterizations for such transport based on idealized laminar or mean-field models. Unfortunately, recent attempts to model this transport in global simulations have produced results that are not consistent with any of these idealized models. In an effort to explain the discrepancies between global simulations and idealized models, here we use three-dimensional local Cartesian simulations of compressible convection to study the efficiency of transport by meridional flows belowmore » a convection zone in several parameter regimes of relevance to the Sun and solar-type stars. In these local simulations we are able to establish the correct ordering of dynamical timescales, although the separation of the timescales remains unrealistic. We find that, even though the generation of internal waves by convective overshoot produces a high degree of time dependence in the meridional flow field, the mean flow has the qualitative behavior predicted by laminar, 'balanced' models. In particular, we observe a progressive deepening, or 'burrowing', of the mean circulation if the local Eddington-Sweet timescale is shorter than the viscous diffusion timescale. Such burrowing is a robust prediction of laminar models in this parameter regime, but has never been observed in any previous numerical simulation. We argue that previous simulations therefore underestimate the transport by meridional flows.« less

Hydrogen Bond Switching among Flavin and Amino Acid Side Chains in the BLUF Photoreceptor Observed by Ultrafast Infrared Spectroscopy

PubMed Central

Bonetti, Cosimo; Mathes, Tilo; van Stokkum, Ivo H. M.; Mullen, Katharine M.; Groot, Marie-Louise; van Grondelle, Rienk; Hegemann, Peter; Kennis, John T. M.

2008-01-01

BLUF domains constitute a recently discovered class of photoreceptor proteins found in bacteria and eukaryotic algae. BLUF domains are blue-light sensitive through a FAD cofactor that is involved in an extensive hydrogen-bond network with nearby amino acid side chains, including a highly conserved tyrosine and glutamine. The participation of particular amino acid side chains in the ultrafast hydrogen-bond switching reaction with FAD that underlies photoactivation of BLUF domains is assessed by means of ultrafast infrared spectroscopy. Blue-light absorption by FAD results in formation of FAD•− and a bleach of the tyrosine ring vibrational mode on a picosecond timescale, showing that electron transfer from tyrosine to FAD constitutes the primary photochemistry. This interpretation is supported by the absence of a kinetic isotope effect on the fluorescence decay on H/D exchange. Subsequent protonation of FAD•− to result in FADH• on a picosecond timescale is evidenced by the appearance of a N-H bending mode at the FAD N5 protonation site and of a FADH• C=N stretch marker mode, with tyrosine as the likely proton donor. FADH• is reoxidized in 67 ps (180 ps in D2O) to result in a long-lived hydrogen-bond switched network around FAD. This hydrogen-bond switch shows infrared signatures from the C-OH stretch of tyrosine and the FAD C4=O and C=N stretches, which indicate increased hydrogen-bond strength at all these sites. The results support a previously hypothesized rotation of glutamine by ∼180° through a light-driven radical-pair mechanism as the determinant of the hydrogen-bond switch. PMID:18708458

Temperature Induced Syllable Breaking Unveils Nonlinearly Interacting Timescales in Birdsong Motor Pathway

PubMed Central

Goldin, Matías A.; Alonso, Leandro M.; Alliende, Jorge A.; Goller, Franz; Mindlin, Gabriel B.

2013-01-01

The nature of telencephalic control over premotor and motor circuits is debated. Hypotheses range from complete usurping of downstream circuitry to highly interactive mechanisms of control. We show theoretically and experimentally, that telencephalic song motor control in canaries is consistent with a highly interactive strategy. As predicted from a theoretical model of respiratory control, mild cooling of a forebrain nucleus (HVC) led to song stretching, but further cooling caused progressive restructuring of song, consistent with the hypothesis that respiratory gestures are subharmonic responses to a timescale present in the output of HVC. This interaction between a life-sustaining motor function (respiration) and telencephalic song motor control suggests a more general mechanism of how nonlinear integration of evolutionarily new brain structures into existing circuitry gives rise to diverse, new behavior. PMID:23818988

Temperature induced syllable breaking unveils nonlinearly interacting timescales in birdsong motor pathway.

PubMed

Goldin, Matías A; Alonso, Leandro M; Alliende, Jorge A; Goller, Franz; Mindlin, Gabriel B

2013-01-01

The nature of telencephalic control over premotor and motor circuits is debated. Hypotheses range from complete usurping of downstream circuitry to highly interactive mechanisms of control. We show theoretically and experimentally, that telencephalic song motor control in canaries is consistent with a highly interactive strategy. As predicted from a theoretical model of respiratory control, mild cooling of a forebrain nucleus (HVC) led to song stretching, but further cooling caused progressive restructuring of song, consistent with the hypothesis that respiratory gestures are subharmonic responses to a timescale present in the output of HVC. This interaction between a life-sustaining motor function (respiration) and telencephalic song motor control suggests a more general mechanism of how nonlinear integration of evolutionarily new brain structures into existing circuitry gives rise to diverse, new behavior.

Modeling temporal and large-scale spatial variability of soil respiration from soil water availability, temperature and vegetation productivity indices

NASA Astrophysics Data System (ADS)

Reichstein, Markus; Rey, Ana; Freibauer, Annette; Tenhunen, John; Valentini, Riccardo; Banza, Joao; Casals, Pere; Cheng, Yufu; Grünzweig, Jose M.; Irvine, James; Joffre, Richard; Law, Beverly E.; Loustau, Denis; Miglietta, Franco; Oechel, Walter; Ourcival, Jean-Marc; Pereira, Joao S.; Peressotti, Alessandro; Ponti, Francesca; Qi, Ye; Rambal, Serge; Rayment, Mark; Romanya, Joan; Rossi, Federica; Tedeschi, Vanessa; Tirone, Giampiero; Xu, Ming; Yakir, Dan

2003-12-01

Field-chamber measurements of soil respiration from 17 different forest and shrubland sites in Europe and North America were summarized and analyzed with the goal to develop a model describing seasonal, interannual and spatial variability of soil respiration as affected by water availability, temperature, and site properties. The analysis was performed at a daily and at a monthly time step. With the daily time step, the relative soil water content in the upper soil layer expressed as a fraction of field capacity was a good predictor of soil respiration at all sites. Among the site variables tested, those related to site productivity (e.g., leaf area index) correlated significantly with soil respiration, while carbon pool variables like standing biomass or the litter and soil carbon stocks did not show a clear relationship with soil respiration. Furthermore, it was evidenced that the effect of precipitation on soil respiration stretched beyond its direct effect via soil moisture. A general statistical nonlinear regression model was developed to describe soil respiration as dependent on soil temperature, soil water content, and site-specific maximum leaf area index. The model explained nearly two thirds of the temporal and intersite variability of soil respiration with a mean absolute error of 0.82 μmol m-2 s-1. The parameterized model exhibits the following principal properties: (1) At a relative amount of upper-layer soil water of 16% of field capacity, half-maximal soil respiration rates are reached. (2) The apparent temperature sensitivity of soil respiration measured as Q10 varies between 1 and 5 depending on soil temperature and water content. (3) Soil respiration under reference moisture and temperature conditions is linearly related to maximum site leaf area index. At a monthly timescale, we employed the approach by [2002] that used monthly precipitation and air temperature to globally predict soil respiration (T&P model). While this model was able to explain some of the month-to-month variability of soil respiration, it failed to capture the intersite variability, regardless of whether the original or a new optimized model parameterization was used. In both cases, the residuals were strongly related to maximum site leaf area index. Thus, for a monthly timescale, we developed a simple T&P&LAI model that includes leaf area index as an additional predictor of soil respiration. This extended but still simple model performed nearly as well as the more detailed time step model and explained 50% of the overall and 65% of the site-to-site variability. Consequently, better estimates of globally distributed soil respiration should be obtained with the new model driven by satellite estimates of leaf area index. Before application at the continental or global scale, this approach should be further tested in boreal, cold-temperate, and tropical biomes as well as for non-woody vegetation.

Connecting the failure of K-theory inside and above vegetation canopies and ejection-sweep cycles by a large eddy simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Banerjee, Tirtha; De Roo, Frederik; Mauder, Matthias

Parameterizations of biosphere-atmosphere interaction processes in climate models and other hydrological applications require characterization of turbulent transport of momentum and scalars between vegetation canopies and the atmosphere, which is often modeled using a turbulent analogy to molecular diffusion processes. However, simple flux-gradient approaches (K-theory) fail for canopy turbulence. One cause is turbulent transport by large coherent eddies at the canopy scale, which can be linked to sweep-ejection events, and bear signatures of non-local organized eddy motions. K-theory, that parameterizes the turbulent flux or stress proportional to the local concentration or velocity gradient, fails to account for these non-local organized motions. The connection to sweep-ejection cycles and the local turbulent flux can be traced back to the turbulence triple momentmore » $$\\overline{C'W'W'}$$. In this work, we use large-eddy simulation to investigate the diagnostic connection between the failure of K-theory and sweep-ejection motions. Analyzed schemes are quadrant analysis (QA) and a complete and incomplete cumulant expansion (CEM and ICEM) method. The latter approaches introduce a turbulence timescale in the modeling. Furthermore, we find that the momentum flux needs a different formulation for the turbulence timescale than the sensible heat flux. In conclusion, accounting for buoyancy in stratified conditions is also deemed to be important in addition to accounting for non-local events to predict the correct momentum or scalar fluxes.« less

Connecting the failure of K-theory inside and above vegetation canopies and ejection-sweep cycles by a large eddy simulation

DOE PAGES

Banerjee, Tirtha; De Roo, Frederik; Mauder, Matthias

2017-10-19

Parameterizations of biosphere-atmosphere interaction processes in climate models and other hydrological applications require characterization of turbulent transport of momentum and scalars between vegetation canopies and the atmosphere, which is often modeled using a turbulent analogy to molecular diffusion processes. However, simple flux-gradient approaches (K-theory) fail for canopy turbulence. One cause is turbulent transport by large coherent eddies at the canopy scale, which can be linked to sweep-ejection events, and bear signatures of non-local organized eddy motions. K-theory, that parameterizes the turbulent flux or stress proportional to the local concentration or velocity gradient, fails to account for these non-local organized motions. The connection to sweep-ejection cycles and the local turbulent flux can be traced back to the turbulence triple momentmore » $$\\overline{C'W'W'}$$. In this work, we use large-eddy simulation to investigate the diagnostic connection between the failure of K-theory and sweep-ejection motions. Analyzed schemes are quadrant analysis (QA) and a complete and incomplete cumulant expansion (CEM and ICEM) method. The latter approaches introduce a turbulence timescale in the modeling. Furthermore, we find that the momentum flux needs a different formulation for the turbulence timescale than the sensible heat flux. In conclusion, accounting for buoyancy in stratified conditions is also deemed to be important in addition to accounting for non-local events to predict the correct momentum or scalar fluxes.« less

The Hubbard Dimer: A Complete DFT Solution to a Many-Body Problem

NASA Astrophysics Data System (ADS)

Smith, Justin; Carrascal, Diego; Ferrer, Jaime; Burke, Kieron

2015-03-01

In this work we explain the relationship between density functional theory and strongly correlated models using the simplest possible example, the two-site asymmetric Hubbard model. We discuss the connection between the lattice and real-space and how this is a simple model for stretched H2. We can solve this elementary example analytically, and with that we can illuminate the underlying logic and aims of DFT. While the many-body solution is analytic, the density functional is given only implicitly. We overcome this difficulty by creating a highly accurate parameterization of the exact function. We use this parameterization to perform benchmark calculations of correlation kinetic energy, the adiabatic connection, etc. We also test Hartree-Fock and the Bethe Ansatz Local Density Approximation. We also discuss and illustrate the derivative discontinuity in the exchange-correlation energy and the infamous gap problem in DFT. DGE-1321846, DE-FG02-08ER46496.

The terminal area simulation system. Volume 1: Theoretical formulation

NASA Technical Reports Server (NTRS)

Proctor, F. H.

1987-01-01

A three-dimensional numerical cloud model was developed for the general purpose of studying convective phenomena. The model utilizes a time splitting integration procedure in the numerical solution of the compressible nonhydrostatic primitive equations. Turbulence closure is achieved by a conventional first-order diagnostic approximation. Open lateral boundaries are incorporated which minimize wave reflection and which do not induce domain-wide mass trends. Microphysical processes are governed by prognostic equations for potential temperature water vapor, cloud droplets, ice crystals, rain, snow, and hail. Microphysical interactions are computed by numerous Orville-type parameterizations. A diagnostic surface boundary layer is parameterized assuming Monin-Obukhov similarity theory. The governing equation set is approximated on a staggered three-dimensional grid with quadratic-conservative central space differencing. Time differencing is approximated by the second-order Adams-Bashforth method. The vertical grid spacing may be either linear or stretched. The model domain may translate along with a convective cell, even at variable speeds.

Mixing parametrizations for ocean climate modelling

NASA Astrophysics Data System (ADS)

Gusev, Anatoly; Moshonkin, Sergey; Diansky, Nikolay; Zalesny, Vladimir

2016-04-01

The algorithm is presented of splitting the total evolutionary equations for the turbulence kinetic energy (TKE) and turbulence dissipation frequency (TDF), which is used to parameterize the viscosity and diffusion coefficients in ocean circulation models. The turbulence model equations are split into the stages of transport-diffusion and generation-dissipation. For the generation-dissipation stage, the following schemes are implemented: the explicit-implicit numerical scheme, analytical solution and the asymptotic behavior of the analytical solutions. The experiments were performed with different mixing parameterizations for the modelling of Arctic and the Atlantic climate decadal variability with the eddy-permitting circulation model INMOM (Institute of Numerical Mathematics Ocean Model) using vertical grid refinement in the zone of fully developed turbulence. The proposed model with the split equations for turbulence characteristics is similar to the contemporary differential turbulence models, concerning the physical formulations. At the same time, its algorithm has high enough computational efficiency. Parameterizations with using the split turbulence model make it possible to obtain more adequate structure of temperature and salinity at decadal timescales, compared to the simpler Pacanowski-Philander (PP) turbulence parameterization. Parameterizations with using analytical solution or numerical scheme at the generation-dissipation step of the turbulence model leads to better representation of ocean climate than the faster parameterization using the asymptotic behavior of the analytical solution. At the same time, the computational efficiency left almost unchanged relative to the simple PP parameterization. Usage of PP parametrization in the circulation model leads to realistic simulation of density and circulation with violation of T,S-relationships. This error is majorly avoided with using the proposed parameterizations containing the split turbulence model. The high sensitivity of the eddy-permitting circulation model to the definition of mixing is revealed, which is associated with significant changes of density fields in the upper baroclinic ocean layer over the total considered area. For instance, usage of the turbulence parameterization instead of PP algorithm leads to increasing circulation velocity in the Gulf Stream and North Atlantic Current, as well as the subpolar cyclonic gyre in the North Atlantic and Beaufort Gyre in the Arctic basin are reproduced more realistically. Consideration of the Prandtl number as a function of the Richardson number significantly increases the modelling quality. The research was supported by the Russian Foundation for Basic Research (grant № 16-05-00534) and the Council on the Russian Federation President Grants (grant № MK-3241.2015.5)

A Two-Timescale Response of the Southern Ocean to Ozone Depletion: Importance of the Background State

NASA Astrophysics Data System (ADS)

Seviour, W.; Waugh, D.; Gnanadesikan, A.

2016-02-01

It has been recently suggested that the response of Southern Ocean sea-ice extent to stratospheric ozone depletion is time-dependent; that the ocean surface initially cools due to enhanced northward Ekman drift caused by a poleward shift in the eddy-driven jet, and then warms after some time due to upwelling of warm waters from below the mixed layer. It is therefore possible that ozone depletion could act to favor a short-term increase in sea-ice extent. However, many uncertainties remain in understanding this mechanism, with different models showing widely differing time-scales and magnitudes of the response. Here, we analyze an ensemble of coupled model simulations with a step-function ozone perturbation. The two-timescale response is present with an approximately 30 year initial cooling period. The response is further shown to be highly dependent upon the background ocean temperature and salinity stratification, which is influenced by both natural internal variability and the isopycnal eddy mixing parameterization. It is suggested that the majority of inter-model differences in the Southern Ocean response to ozone depletion are caused by differences in stratification.

Rainfall From Resolved Rather Than Parameterized Processes Better Represents the Present-Day and Climate Change Response of Moderate Rates in the Community Atmosphere Model

DOE PAGES

Kooperman, Gabriel J.; Pritchard, Michael S.; O'Brien, Travis A.; ...

2018-04-01

Deficiencies in the parameterizations of convection used in global climate models often lead to a distorted representation of the simulated rainfall intensity distribution (i.e., too much rainfall from weak rain rates). While encouraging improvements in high percentile rainfall intensity have been found as the horizontal resolution of the Community Atmosphere Model is increased to ~25 km, we demonstrate no corresponding improvement in the moderate rain rates that generate the majority of accumulated rainfall. Using a statistical framework designed to emphasize links between precipitation intensity and accumulated rainfall beyond just the frequency distribution, we show that CAM cannot realistically simulate moderatemore » rain rates, and cannot capture their intensification with climate change, even as resolution is increased. However, by separating the parameterized convective and large-scale resolved contributions to total rainfall, we find that the intensity, geographic pattern, and climate change response of CAM's large-scale rain rates are more consistent with observations (TRMM 3B42), superparameterization, and theoretical expectations, despite issues with parameterized convection. Increasing CAM's horizontal resolution does improve the representation of total rainfall intensity, but not due to changes in the intensity of large-scale rain rates, which are surprisingly insensitive to horizontal resolution. Rather, improvements occur through an increase in the relative contribution of the large-scale component to the total amount of accumulated rainfall. Analysis of sensitivities to convective timescale and entrainment rate confirm the importance of these parameters in the possible development of scale-aware parameterizations, but also reveal unrecognized trade-offs from the entanglement of precipitation frequency and total amount.« less

Rainfall From Resolved Rather Than Parameterized Processes Better Represents the Present-Day and Climate Change Response of Moderate Rates in the Community Atmosphere Model

NASA Astrophysics Data System (ADS)

Kooperman, Gabriel J.; Pritchard, Michael S.; O'Brien, Travis A.; Timmermans, Ben W.

2018-04-01

Deficiencies in the parameterizations of convection used in global climate models often lead to a distorted representation of the simulated rainfall intensity distribution (i.e., too much rainfall from weak rain rates). While encouraging improvements in high percentile rainfall intensity have been found as the horizontal resolution of the Community Atmosphere Model is increased to ˜25 km, we demonstrate no corresponding improvement in the moderate rain rates that generate the majority of accumulated rainfall. Using a statistical framework designed to emphasize links between precipitation intensity and accumulated rainfall beyond just the frequency distribution, we show that CAM cannot realistically simulate moderate rain rates, and cannot capture their intensification with climate change, even as resolution is increased. However, by separating the parameterized convective and large-scale resolved contributions to total rainfall, we find that the intensity, geographic pattern, and climate change response of CAM's large-scale rain rates are more consistent with observations (TRMM 3B42), superparameterization, and theoretical expectations, despite issues with parameterized convection. Increasing CAM's horizontal resolution does improve the representation of total rainfall intensity, but not due to changes in the intensity of large-scale rain rates, which are surprisingly insensitive to horizontal resolution. Rather, improvements occur through an increase in the relative contribution of the large-scale component to the total amount of accumulated rainfall. Analysis of sensitivities to convective timescale and entrainment rate confirm the importance of these parameters in the possible development of scale-aware parameterizations, but also reveal unrecognized trade-offs from the entanglement of precipitation frequency and total amount.

Rainfall From Resolved Rather Than Parameterized Processes Better Represents the Present‐Day and Climate Change Response of Moderate Rates in the Community Atmosphere Model

PubMed Central

Pritchard, Michael S.; O'Brien, Travis A.; Timmermans, Ben W.

2018-01-01

Abstract Deficiencies in the parameterizations of convection used in global climate models often lead to a distorted representation of the simulated rainfall intensity distribution (i.e., too much rainfall from weak rain rates). While encouraging improvements in high percentile rainfall intensity have been found as the horizontal resolution of the Community Atmosphere Model is increased to ∼25 km, we demonstrate no corresponding improvement in the moderate rain rates that generate the majority of accumulated rainfall. Using a statistical framework designed to emphasize links between precipitation intensity and accumulated rainfall beyond just the frequency distribution, we show that CAM cannot realistically simulate moderate rain rates, and cannot capture their intensification with climate change, even as resolution is increased. However, by separating the parameterized convective and large‐scale resolved contributions to total rainfall, we find that the intensity, geographic pattern, and climate change response of CAM's large‐scale rain rates are more consistent with observations (TRMM 3B42), superparameterization, and theoretical expectations, despite issues with parameterized convection. Increasing CAM's horizontal resolution does improve the representation of total rainfall intensity, but not due to changes in the intensity of large‐scale rain rates, which are surprisingly insensitive to horizontal resolution. Rather, improvements occur through an increase in the relative contribution of the large‐scale component to the total amount of accumulated rainfall. Analysis of sensitivities to convective timescale and entrainment rate confirm the importance of these parameters in the possible development of scale‐aware parameterizations, but also reveal unrecognized trade‐offs from the entanglement of precipitation frequency and total amount. PMID:29861837

Rainfall From Resolved Rather Than Parameterized Processes Better Represents the Present-Day and Climate Change Response of Moderate Rates in the Community Atmosphere Model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kooperman, Gabriel J.; Pritchard, Michael S.; O'Brien, Travis A.

Deficiencies in the parameterizations of convection used in global climate models often lead to a distorted representation of the simulated rainfall intensity distribution (i.e., too much rainfall from weak rain rates). While encouraging improvements in high percentile rainfall intensity have been found as the horizontal resolution of the Community Atmosphere Model is increased to ~25 km, we demonstrate no corresponding improvement in the moderate rain rates that generate the majority of accumulated rainfall. Using a statistical framework designed to emphasize links between precipitation intensity and accumulated rainfall beyond just the frequency distribution, we show that CAM cannot realistically simulate moderatemore » rain rates, and cannot capture their intensification with climate change, even as resolution is increased. However, by separating the parameterized convective and large-scale resolved contributions to total rainfall, we find that the intensity, geographic pattern, and climate change response of CAM's large-scale rain rates are more consistent with observations (TRMM 3B42), superparameterization, and theoretical expectations, despite issues with parameterized convection. Increasing CAM's horizontal resolution does improve the representation of total rainfall intensity, but not due to changes in the intensity of large-scale rain rates, which are surprisingly insensitive to horizontal resolution. Rather, improvements occur through an increase in the relative contribution of the large-scale component to the total amount of accumulated rainfall. Analysis of sensitivities to convective timescale and entrainment rate confirm the importance of these parameters in the possible development of scale-aware parameterizations, but also reveal unrecognized trade-offs from the entanglement of precipitation frequency and total amount.« less

Methane Sensitivity to Perturbations in Tropospheric Oxidizing Capacity

NASA Technical Reports Server (NTRS)

Yegorova, Elena; Duncan, Bryan

2011-01-01

Methane is an important greenhouse gas and has a 25 times greater global warming potential than CO2 on a century timescale. Yet there are considerable uncertainties in the magnitude and variability of its sources and sinks. The response of the coupled non-linear methane-carbon monoxide-hydroxyl radical (OH) system is important in determining the tropospheric oxidizing capacity. Using the NASA Goddard Earth Observing System, Version 5 (GEOS-5) chemistry climate model, we study the response of methane to perturbations of OH and wetland emissions. We use a computationally-efficient option of the GEOS-5 CCM that includes an OH parameterization that accurately represents OH predicted by a full chemical mechanism. The OH parameterization allows for studying non-linear CH4-CO-OH feedbacks in computationally fast sensitivity experiments. We compare our results with surface observations (GMD) and discuss the range of uncertainty in OH and wetland emissions required to bring modeling results in better agreement with surface observations. Our results can be used to improve projections of methane emissions and methane growth.

Heterogeneous chain dynamics and aggregate lifetimes in precise acid-containing polyethylenes: Experiments and simulations

DOE PAGES

Middleton, L. Robert; Tarver, Jacob D.; Cordaro, Joseph; ...

2016-11-10

Melt state dynamics for a series of strictly linear polyethylenes with precisely spaced associating functional groups were investigated. The periodic pendant acrylic acid groups form hydrogen-bonded acid aggregates within the polyethylene (PE) matrix. The dynamics of these nanoscale heterogeneous morphologies were investigated from picosecond to nanosecond timescales by both quasi-elastic neutron scattering (QENS) measurements and fully atomistic molecular dynamics (MD) simulations. Two dynamic processes were observed. The faster dynamic processes which occur at the picosecond timescales are compositionally insensitive and indicative of spatially restricted local motions. The slower dynamic processes are highly composition dependent and indicate the structural relaxation ofmore » the polymer backbone. Higher acid contents, or shorter PE spacers between pendant acid groups, slow the structural relaxation timescale and increase the stretching parameter (β) of the structural relaxation. Additionally, the dynamics of specific hydrogen atom positions along the backbone correlate structural heterogeneity imposed by the associating acid groups with a mobility gradient along the polymer backbone. At time intervals (<2 ns), the mean-squared displacements for the four methylene groups closest to the acid groups are up to 10 times smaller than those of methylene groups further from the acid groups. At longer timescales acid aggregates rearrange and the chain dynamics of the slow, near-aggregate regions and the faster bridge regions converge, implying a characteristic timescale for the passage of chains between aggregates. As a result, the characterization of the nanoscale chain dynamics in these associating polymer systems both provides validation of simulation force fields and provides understanding of heterogeneous chain dynamics in associating polymers.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Middleton, L. Robert; Tarver, Jacob D.; Cordaro, Joseph

Melt state dynamics for a series of strictly linear polyethylenes with precisely spaced associating functional groups were investigated. The periodic pendant acrylic acid groups form hydrogen-bonded acid aggregates within the polyethylene (PE) matrix. The dynamics of these nanoscale heterogeneous morphologies were investigated from picosecond to nanosecond timescales by both quasi-elastic neutron scattering (QENS) measurements and fully atomistic molecular dynamics (MD) simulations. Two dynamic processes were observed. The faster dynamic processes which occur at the picosecond timescales are compositionally insensitive and indicative of spatially restricted local motions. The slower dynamic processes are highly composition dependent and indicate the structural relaxation ofmore » the polymer backbone. Higher acid contents, or shorter PE spacers between pendant acid groups, slow the structural relaxation timescale and increase the stretching parameter (β) of the structural relaxation. Additionally, the dynamics of specific hydrogen atom positions along the backbone correlate structural heterogeneity imposed by the associating acid groups with a mobility gradient along the polymer backbone. At time intervals (<2 ns), the mean-squared displacements for the four methylene groups closest to the acid groups are up to 10 times smaller than those of methylene groups further from the acid groups. At longer timescales acid aggregates rearrange and the chain dynamics of the slow, near-aggregate regions and the faster bridge regions converge, implying a characteristic timescale for the passage of chains between aggregates. As a result, the characterization of the nanoscale chain dynamics in these associating polymer systems both provides validation of simulation force fields and provides understanding of heterogeneous chain dynamics in associating polymers.« less

Modeling the Conformation-Specific Infrared Spectra of N-Alkylbenzenes

NASA Astrophysics Data System (ADS)

Tabor, Daniel P.; Sibert, Edwin; Hewett, Daniel M.; Korn, Joseph A.; Zwier, Timothy S.

2016-06-01

Conformation-specific UV-IR double resonance spectra are presented for n-alkylbenzenes. With the aid of a local mode Hamiltonian that includes the effects of stretch-bend Fermi coupling, the spectra of ethyl, n-propyl, and n-butylbenzene are assigned to individual conformers. These molecules allow for further development of the work on a first principles method for calculating alkyl stretch spectra. Due to the consistency of the anharmonic couplings from conformer to conformer, construction of the model Hamiltonian for a given conformer only requires a harmonic frequency calculation at the conformer's minimum geometry as an input. The model Hamiltonian can be parameterized with either density functional theory or MP2 electronic structure calculations. The relative strengths and weaknesses of these methods are evaluated, including their predictions of the relative energetics of the conformers. Finally, the IR spectra for conformers that have the alkyl chain bend back and interact with the π cloud of the benzene ring are modeled.

Evaluating Lightning-generated NOx (LNOx) Parameterization based on Cloud Top Height at Resolutions with Partially-resolved Convection for Upper Tropospheric Chemistry Studies

NASA Astrophysics Data System (ADS)

Wong, J.; Barth, M. C.; Noone, D. C.

2012-12-01

Lightning-generated nitrogen oxides (LNOx) is an important precursor to tropospheric ozone production. With a meteorological time-scale variability similar to that of the ozone chemical lifetime, it can nonlinearly perturb tropospheric ozone concentration. Coupled with upper-air circulation patterns, LNOx can accumulate in significant amount in the upper troposphere with other precursors, thus enhancing ozone production (see attached figure). While LNOx emission has been included and tuned extensively in global climate models, its inclusions in regional chemistry models are seldom tested. Here we present a study that evaluates the frequently used Price and Rind parameterization based on cloud-top height at resolutions that partially resolve deep convection using the Weather Research and Forecasting model with Chemistry (WRF-Chem) over the contiguous United States. With minor modifications, the parameterization is shown to generate integrated flash counts close to those observed. However, the modeled frequency distribution of cloud-to-ground flashes do not represent well for storms with high flash rates, bringing into question the applicability of the intra-cloud/ground partitioning (IC:CG) formulation of Price and Rind in some studies. Resolution dependency also requires attention when sub-grid cloud-tops are used instead of the originally intended grid-averaged cloud-top. LNOx passive tracers being gathered by monsoonal upper tropospheric anticyclone.

Calculation of Rate Spectra from Noisy Time Series Data

PubMed Central

Voelz, Vincent A.; Pande, Vijay S.

2011-01-01

As the resolution of experiments to measure folding kinetics continues to improve, it has become imperative to avoid bias that may come with fitting data to a predetermined mechanistic model. Towards this end, we present a rate spectrum approach to analyze timescales present in kinetic data. Computing rate spectra of noisy time series data via numerical discrete inverse Laplace transform is an ill-conditioned inverse problem, so a regularization procedure must be used to perform the calculation. Here, we show the results of different regularization procedures applied to noisy multi-exponential and stretched exponential time series, as well as data from time-resolved folding kinetics experiments. In each case, the rate spectrum method recapitulates the relevant distribution of timescales present in the data, with different priors on the rate amplitudes naturally corresponding to common biases toward simple phenomenological models. These results suggest an attractive alternative to the “Occam’s razor” philosophy of simply choosing models with the fewest number of relaxation rates. PMID:22095854

An Efficient and Imperfect Model for Gravel-Bed Braided River Morphodynamics: Numerical Simulations as Exploratory Tools

NASA Astrophysics Data System (ADS)

Kasprak, A.; Brasington, J.; Hafen, K.; Wheaton, J. M.

2015-12-01

Numerical models that predict channel evolution through time are an essential tool for investigating processes that occur over timescales which render field observation intractable. However, available morphodynamic models generally take one of two approaches to the complex problem of computing morphodynamics, resulting in oversimplification of the relevant physics (e.g. cellular models) or faithful, yet computationally intensive, representations of the hydraulic and sediment transport processes at play. The practical implication of these approaches is that river scientists must often choose between unrealistic results, in the case of the former, or computational demands that render modeling realistic spatiotemporal scales of channel evolution impossible. Here we present a new modeling framework that operates at the timescale of individual competent flows (e.g. floods), and uses a highly-simplified sediment transport routine that moves volumes of material according to morphologically-derived characteristic transport distances, or path lengths. Using this framework, we have constructed an open-source morphodynamic model, termed MoRPHED, which is here applied, and its validity investigated, at timescales ranging from a single event to a decade on two braided rivers in the UK and New Zealand. We do not purport that MoRPHED is the best, nor even an adequate, tool for modeling braided river dynamics at this range of timescales. Rather, our goal in this research is to explore the utility, feasibility, and sensitivity of an event-scale, path-length-based modeling framework for predicting braided river dynamics. To that end, we further explore (a) which processes are naturally emergent and which must be explicitly parameterized in the model, (b) the sensitivity of the model to the choice of particle travel distance, and (c) whether an event-scale model timestep is adequate for producing braided channel dynamics. The results of this research may inform techniques for future morphodynamic modeling that seeks to maximize computational resources while modeling fluvial dynamics at the timescales of change.

Multi-scale enhancement of climate prediction over land by improving the model sensitivity to vegetation variability

NASA Astrophysics Data System (ADS)

Alessandri, A.; Catalano, F.; De Felice, M.; Hurk, B. V. D.; Doblas-Reyes, F. J.; Boussetta, S.; Balsamo, G.; Miller, P. A.

2017-12-01

Here we demonstrate, for the first time, that the implementation of a realistic representation of vegetation in Earth System Models (ESMs) can significantly improve climate simulation and prediction across multiple time-scales. The effective sub-grid vegetation fractional coverage vary seasonally and at interannual time-scales in response to leaf-canopy growth, phenology and senescence. Therefore it affects biophysical parameters such as the surface resistance to evapotranspiration, albedo, roughness lenght, and soil field capacity. To adequately represent this effect in the EC-Earth ESM, we included an exponential dependence of the vegetation cover on the Leaf Area Index.By comparing two sets of simulations performed with and without the new variable fractional-coverage parameterization, spanning from centennial (20th Century) simulations and retrospective predictions to the decadal (5-years), seasonal (2-4 months) and weather (4 days) time-scales, we show for the first time a significant multi-scale enhancement of vegetation impacts in climate simulation and prediction over land. Particularly large effects at multiple time scales are shown over boreal winter middle-to-high latitudes over Canada, West US, Eastern Europe, Russia and eastern Siberia due to the implemented time-varying shadowing effect by tree-vegetation on snow surfaces. Over Northern Hemisphere boreal forest regions the improved representation of vegetation-cover consistently correct the winter warm biases, improves the climate change sensitivity, the decadal potential predictability as well as the skill of forecasts at seasonal and weather time-scales. Significant improvements of the prediction of 2m temperature and rainfall are also shown over transitional land surface hot spots. Both the potential predictability at decadal time-scale and seasonal-forecasts skill are enhanced over Sahel, North American Great Plains, Nordeste Brazil and South East Asia, mainly related to improved performance in the surface evapotranspiration.Above results are discussed in a peer-review paper just being accepted for publication on Climate Dynamics (Alessandri et al., 2017; doi:10.1007/s00382-017-3766-y).

Systematic errors in the simulation of the Asian summer monsoon: the role of rainfall variability on a range of time and space scales

NASA Astrophysics Data System (ADS)

Martin, Gill; Levine, Richard; Klingaman, Nicholas; Bush, Stephanie; Turner, Andrew; Woolnough, Steven

2015-04-01

Despite considerable efforts worldwide to improve model simulations of the Asian summer monsoon, significant biases still remain in climatological seasonal mean rainfall distribution, timing of the onset, and northward and eastward extent of the monsoon domain (Sperber et al., 2013). Many modelling studies have shown sensitivity to convection and boundary layer parameterization, cloud microphysics and land surface properties, as well as model resolution. Here we examine the problems in representing short-timescale rainfall variability (related to convection parameterization), problems in representing synoptic-scale systems such as monsoon depressions (related to model resolution), and the relationship of each of these with longer-term systematic biases. Analysis of the spatial distribution of rainfall intensity on a range of timescales ranging from ~30 minutes to daily, in the MetUM and in observations (where available), highlights how rainfall biases in the South Asian monsoon region on different timescales in different regions can be achieved in models through a combination of the incorrect frequency and/or intensity of rainfall. Over the Indian land area, the typical dry bias is related to sub-daily rainfall events being too infrequent, despite being too intense when they occur. In contrast, the wet bias regions over the equatorial Indian Ocean are mainly related to too frequent occurrence of lower-than-observed 3-hourly rainfall accumulations which result in too frequent occurrence of higher-than-observed daily rainfall accumulations. This analysis sheds light on the model deficiencies behind the climatological seasonal mean rainfall biases that many models exhibit in this region. Changing physical parameterizations alters this behaviour, with associated adjustments in the climatological rainfall distribution, although the latter is not always improved (Bush et al., 2014). This suggests a more complex interaction between the diabatic heating and the large-scale circulation than is indicated by the intensity and frequency of rainfall alone. Monsoon depressions and low pressure systems are important contributors to monsoon rainfall over central and northern India, areas where MetUM climate simulations typically show deficient monsoon rainfall. Analysis of MetUM climate simulations at resolutions ranging from N96 (~135km) to N512 (~25km) suggests that at lower resolution the numbers and intensities of monsoon depressions and low pressure systems and their associated rainfall are very low compared with re-analyses/observations. We show that there are substantial increases with horizontal resolution, but resolution is not the only factor. Idealised simulations, either using nudged atmospheric winds or initialised coupled hindcasts, which improve (strengthen) the mean state monsoon and cyclonic circulation over the Indian peninsula, also result in a substantial increase in monsoon depressions and associated rainfall. This suggests that a more realistic representation of monsoon depressions is possible even at lower resolution if the larger-scale systematic error pattern in the monsoon is improved.

Conditional probability of rainfall extremes across multiple durations

NASA Astrophysics Data System (ADS)

Le, Phuong Dong; Leonard, Michael; Westra, Seth

2017-04-01

The conditional probability that extreme rainfall will occur at one location given that it is occurring at another location is critical in engineering design and management circumstances including planning of evacuation routes and the sitting of emergency infrastructure. A challenge with this conditional simulation is that in many situations the interest is not so much the conditional distributions of rainfall of the same duration at two locations, but rather the conditional distribution of flooding in two neighbouring catchments, which may be influenced by rainfall of different critical durations. To deal with this challenge, a model that can consider both spatial and duration dependence of extremes is required. The aim of this research is to develop a model that can take account both spatial dependence and duration dependence into the dependence structure of extreme rainfalls. To achieve this aim, this study is a first attempt at combining extreme rainfall for multiple durations within a spatial extreme model framework based on max-stable process theory. Max-stable processes provide a general framework for modelling multivariate extremes with spatial dependence for just a single duration extreme rainfall. To achieve dependence across multiple timescales, this study proposes a new approach that includes addition elements representing duration dependence of extremes to the covariance matrix of max-stable model. To improve the efficiency of calculation, a re-parameterization proposed by Koutsoyiannis et al. (1998) is used to reduce the number of parameters necessary to be estimated. This re-parameterization enables the GEV parameters to be represented as a function of timescale. A stepwise framework has been adopted to achieve the overall aims of this research. Firstly, the re-parameterization is used to define a new set of common parameters for marginal distribution across multiple durations. Secondly, spatial interpolation of the new parameter set is used to estimate marginal parameters across the full spatial domain. Finally, spatial interpolation result is used as initial condition to estimate dependence parameters via a likelihood function of max-stable model for multiple durations. The Hawkesbury-Nepean catchment near Sydney in Australia was selected as case study for this research. This catchment has 25 sub-daily rain gauges with the minimum record length of 24 years over a region of 300 km × 300 km area. The re-parameterization was applied for each station for durations from 1 hour to 24 hours and then is evaluated by comparing with the at-site fitted GEV. The evaluation showed that the average R2 for all station is around 0.80 with the range from 0.26 to 1.0. The output of re-parameterization then was used to construct the spatial surface based on covariates including longitude, latitude, and elevation. The dependence model showed good agreements between empirical extremal coefficient and theoretical extremal coefficient for multiple durations. For the overall model, a leave-one-out cross-validation for all stations showed it works well for 20 out of 25 stations. The potential application of this model framework was illustrated through a conditional map of return period and return level across multiple durations, both of which are important for engineering design and management.

Long-range transport of black carbon to the Pacific Ocean and its dependence on aging timescale

NASA Astrophysics Data System (ADS)

Zhang, J.; Liu, J.; Tao, S.; Ban-Weiss, G. A.

2015-06-01

Improving the ability of global models to predict concentrations of black carbon (BC) over the Pacific Ocean is essential to evaluate the impact of BC on marine climate. In this study, we tag BC tracers from 13 source regions around the globe in a global chemical transport model MOZART-4. Numerous sensitivity simulations are carried out varying the aging timescale of BC emitted from each source region. The aging timescale for each source region is optimized by minimizing errors in vertical profiles of BC mass mixing ratios between simulations and HIAPER Pole-to-Pole Observations (HIPPO). For most HIPPO deployments, in the Northern Hemisphere, optimized aging timescales are less than half a day for BC emitted from tropical and mid-latitude source regions, and about 1 week for BC emitted from high latitude regions in all seasons except summer. We find that East Asian emissions contribute most to the BC loading over the North Pacific, while South American, African and Australian emissions dominate BC loadings over the South Pacific. Dominant source regions contributing to BC loadings in other parts of the globe are also assessed. The lifetime of BC originating from East Asia (i.e., the world's largest BC emitter) is found to be only 2.2 days, much shorter than the global average lifetime of 4.9 days, making East Asia's contribution to global burden only 36 % of BC from the second largest emitter, Africa. Thus, evaluating only relative emission rates without accounting for differences in aging timescales and deposition rates is not predictive of the contribution of a given source region to climate impacts. Our simulations indicate that lifetime of BC increases nearly linearly with aging timescale for all source regions. When aging rate is fast, the lifetime of BC is largely determined by factors that control local deposition rates (e.g. precipitation). The sensitivity of lifetime to aging timescale depends strongly on the initial hygroscopicity of freshly emitted BC. Our findings suggest that the aging timescale of BC varies significantly by region and season, and can strongly influence the contribution of source regions to BC burdens around the globe. Improving parameterizations of the aging process for BC is important for enhancing the predictive skill of air quality and climate models. Future observations that investigate the evolution of hygroscopicity of BC as it ages from different source regions to the remote atmosphere are urgently needed.

Long-range transport of black carbon to the Pacific Ocean and its dependence on aging timescale

NASA Astrophysics Data System (ADS)

Zhang, J.; Liu, J.; Tao, S.; Ban-Weiss, G. A.

2015-10-01

Improving the ability of global models to predict concentrations of black carbon (BC) over the Pacific Ocean is essential to evaluate the impact of BC on marine climate. In this study, we tag BC tracers from 13 source regions around the globe in a global chemical transport model, Model for Ozone and Related Chemical Tracers, version 4 (MOZART-4). Numerous sensitivity simulations are carried out varying the aging timescale of BC emitted from each source region. The aging timescale for each source region is optimized by minimizing errors in vertical profiles of BC mass mixing ratios between simulations and HIAPER Pole-to-Pole Observations (HIPPO). For most HIPPO deployments, in the Northern Hemisphere, optimized aging timescales are less than half a day for BC emitted from tropical and midlatitude source regions and about 1 week for BC emitted from high-latitude regions in all seasons except summer. We find that East Asian emissions contribute most to the BC loading over the North Pacific, while South American, African and Australian emissions dominate BC loadings over the South Pacific. Dominant source regions contributing to BC loadings in other parts of the globe are also assessed. The lifetime of BC originating from East Asia (i.e., the world's largest BC emitter) is found to be only 2.2 days, much shorter than the global average lifetime of 4.9 days, making the contribution from East Asia to the global BC burden only 36 % of that from the second largest emitter, Africa. Thus, evaluating only relative emission rates without accounting for differences in aging timescales and deposition rates is not predictive of the contribution of a given source region to climate impacts. Our simulations indicate that the lifetime of BC increases nearly linearly with aging timescale for all source regions. When the aging rate is fast, the lifetime of BC is largely determined by factors that control local deposition rates (e.g., precipitation). The sensitivity of lifetime to aging timescale depends strongly on the initial hygroscopicity of freshly emitted BC. Our findings suggest that the aging timescale of BC varies significantly by region and season and can strongly influence the contribution of source regions to BC burdens around the globe. Therefore, improving parameterizations of the aging process for BC is important for enhancing the predictive skill of global models. Future observations that investigate the evolution of the hygroscopicity of BC as it ages from different source regions to the remote atmosphere are urgently needed.

Alkyl hydrogen atom abstraction reactions of the CN radical with ethanol

NASA Astrophysics Data System (ADS)

Athokpam, Bijyalaxmi; Ramesh, Sai G.

2018-04-01

We present a study of the abstraction of alkyl hydrogen atoms from the β and α positions of ethanol by the CN radical in solution using the Empirical Valence Bond (EVB) method. We have built separate 2 × 2 EVB models for the Hβ and Hα reactions, where the atom transfer is parameterized using ab initio calculations. The intra- and intermolecular potentials of the reactant and product molecules were modelled with the General AMBER Force Field, with some modifications. We have carried out the dynamics in water and chloroform, which are solvents of contrasting polarity. We have computed the potential of mean force for both abstractions in each of the solvents. They are found to have a small and early barrier along the reaction coordinate with a large energy release. Analyzing the solvent structure around the reaction system, we have found two solvents to have little effect on either reaction. Simulating the dynamics from the transition state, we also study the fate of the energies in the HCN vibrational modes. The HCN molecule is born vibrationally hot in the CH stretch in both reactions and additionally in the HCN bends for the Hα abstraction reaction. In the early stage of the dynamics, we find that the CN stretch mode gains energy at the expense of the energy in CH stretch mode.

Revised tuning of Ocean Drilling Program Site 964 and KC01B (Mediterranean) and implications for the δ18O, tephra, calcareous nannofossil, and geomagnetic reversal chronologies of the past 1.1 Myr

NASA Astrophysics Data System (ADS)

Lourens, Lucas J.

2004-09-01

High-resolution color reflectance records of KC01 and KC01B (Calabrian Ridge, Ionian Sea) are presented and compared with a modified spliced high-resolution color reflectance record of Ocean Drilling Program (ODP) Site 964. This comparison revealed that KC01B is characterized by intensive deformation between ~27 and 28.5 m piston depth and that some sapropels are tectonically reduced in thickness. Moreover, the piston coring has caused considerable stretching in the top of KC01 and KC01B. Using a new splice of ODP Site 964 as guide, previous astronomical tuned timescales of KC01B and ODP Site 964 were evaluated. This evaluation resulted in a new sapropel-based astronomical timescale for the last 1.1 Myr. The new timescale implies a much more uniform change in sedimentation rate for the Ionian Sea cores. Two prominent excursions to lighter values in the δ18O record of the planktonic foraminiferal species Globigerinoides ruber occur during marine isotopic stages 12 and 16 applying the new timescale. These shifts correspond with maxima in obliquity and are punctuated by minima in the precession cycle. They are absent in global ice volume records and are interpreted as reflecting a (summer) low-salinity surface water lens that floats on top of extremely saline intermediate and deep waters at times of the very low sea levels during these glacial periods. All biostratigraphic and magnetostratigraphic events found in KC01B and ODP Site 964 were re-dated according to the new timescale, and the ages of 33 tephra layers were reviewed. The new ages for the Calabrian Ridge 2 and 3 magnetic events in the Brunhes are concordant with minima in the global Sint800 composite record, derived from worldwide deep-sea records of relative paleointensity and have been attributed to the Big Lost and La Palma excursions, respectively.

Speech rhythm analysis with decomposition of the amplitude envelope: characterizing rhythmic patterns within and across languages.

PubMed

Tilsen, Sam; Arvaniti, Amalia

2013-07-01

This study presents a method for analyzing speech rhythm using empirical mode decomposition of the speech amplitude envelope, which allows for extraction and quantification of syllabic- and supra-syllabic time-scale components of the envelope. The method of empirical mode decomposition of a vocalic energy amplitude envelope is illustrated in detail, and several types of rhythm metrics derived from this method are presented. Spontaneous speech extracted from the Buckeye Corpus is used to assess the effect of utterance length on metrics, and it is shown how metrics representing variability in the supra-syllabic time-scale components of the envelope can be used to identify stretches of speech with targeted rhythmic characteristics. Furthermore, the envelope-based metrics are used to characterize cross-linguistic differences in speech rhythm in the UC San Diego Speech Lab corpus of English, German, Greek, Italian, Korean, and Spanish speech elicited in read sentences, read passages, and spontaneous speech. The envelope-based metrics exhibit significant effects of language and elicitation method that argue for a nuanced view of cross-linguistic rhythm patterns.

Stochastic modeling of turbulent reacting flows

NASA Technical Reports Server (NTRS)

Fox, R. O.; Hill, J. C.; Gao, F.; Moser, R. D.; Rogers, M. M.

1992-01-01

Direct numerical simulations of a single-step irreversible chemical reaction with non-premixed reactants in forced isotropic turbulence at R(sub lambda) = 63, Da = 4.0, and Sc = 0.7 were made using 128 Fourier modes to obtain joint probability density functions (pdfs) and other statistical information to parameterize and test a Fokker-Planck turbulent mixing model. Preliminary results indicate that the modeled gradient stretching term for an inert scalar is independent of the initial conditions of the scalar field. The conditional pdf of scalar gradient magnitudes is found to be a function of the scalar until the reaction is largely completed. Alignment of concentration gradients with local strain rate and other features of the flow were also investigated.

Structurally detailed coarse-grained model for Sec-facilitated co-translational protein translocation and membrane integration

PubMed Central

Miller, Thomas F.

2017-01-01

We present a coarse-grained simulation model that is capable of simulating the minute-timescale dynamics of protein translocation and membrane integration via the Sec translocon, while retaining sufficient chemical and structural detail to capture many of the sequence-specific interactions that drive these processes. The model includes accurate geometric representations of the ribosome and Sec translocon, obtained directly from experimental structures, and interactions parameterized from nearly 200 μs of residue-based coarse-grained molecular dynamics simulations. A protocol for mapping amino-acid sequences to coarse-grained beads enables the direct simulation of trajectories for the co-translational insertion of arbitrary polypeptide sequences into the Sec translocon. The model reproduces experimentally observed features of membrane protein integration, including the efficiency with which polypeptide domains integrate into the membrane, the variation in integration efficiency upon single amino-acid mutations, and the orientation of transmembrane domains. The central advantage of the model is that it connects sequence-level protein features to biological observables and timescales, enabling direct simulation for the mechanistic analysis of co-translational integration and for the engineering of membrane proteins with enhanced membrane integration efficiency. PMID:28328943

Growing skin: Tissue expansion in pediatric forehead reconstruction

PubMed Central

Zollner, Alexander M.; Buganza Tepole, Adrian; Gosain, Arun K.; Kuhl, Ellen

2011-01-01

Tissue expansion is a common surgical procedure to grow extra skin through controlled mechanical over-stretch. It creates skin that matches the color, texture, and thickness of the surrounding tissue, while minimizing scars and risk of rejection. Despite intense research in tissue expansion and skin growth, there is a clear knowledge gap between heuristic observation and mechanistic understanding of the key phenomena that drive the growth process. Here, we show that a continuum mechanics approach, embedded in a custom-designed finite element model, informed by medical imaging, provides valuable insight into the biomechanics of skin growth. In particular, we model skin growth using the concept of an incompatible growth configuration. We characterize its evolution in time using a second-order growth tensor parameterized in terms of a scalar-valued internal variable, the in-plane area growth. When stretched beyond the physiological level, new skin is created, and the in-plane area growth increases. For the first time, we simulate tissue expansion on a patient-specific geometric model, and predict stress, strain, and area gain at three expanded locations in a pediatric skull: in the scalp, in the forehead, and in the cheek. Our results may help the surgeon to prevent tissue over-stretch and make informed decisions about expander geometry, size, placement, and inflation. We anticipate our study to open new avenues in reconstructive surgery, and enhance treatment for patients with birth defects, burn injuries, or breast tumor removal. PMID:22052000

The importance of terrestrial weathering for climate system modelling on extended timescales: a study with the UVic ESCM

NASA Astrophysics Data System (ADS)

Brault, Marc-Olivier; Matthews, Damon; Mysak, Lawrence

2016-04-01

The chemical erosion of carbonate and silicate rocks is a key process in the global carbon cycle and, through its coupling with calcium carbonate deposition in the ocean, is the primary sink of carbon on geologic timescales. The dynamic interdependence of terrestrial weathering rates with atmospheric temperature and carbon dioxide concentrations is crucial to the regulation of Earth's climate over multi-millennial timescales. However any attempts to develop a modeling context for terrestrial weathering as part of a dynamic climate system are limited, mostly because of the difficulty in adapting the multi-millennial timescales of the implied negative feedback mechanism with those of the atmosphere and ocean. Much of the earlier work on this topic is therefore based on box-model approaches, abandoning spatial variability for the sake of computational efficiency and the possibility to investigate the impact of weathering on climate change over time frames much longer than those allowed by traditional climate system models. As a result we still have but a rudimentary understanding of the chemical weathering feedback mechanism and its effects on ocean biogeochemistry and atmospheric CO2. Here, we introduce a spatially-explicit, rock weathering model into the University of Victoria Earth System Climate Model (UVic ESCM). We use a land map which takes into account a number of different rock lithologies, changes in sea level, as well as an empirical model of the temperature and NPP dependency of weathering rates for the different rock types. We apply this new model to the last deglacial period (c. 21000BP to 13000BP) as well as a future climate change scenario (c. 1800AD to 6000AD+), comparing the results of our 2-D version of the weathering feedback mechanism to simulations using only the box-model parameterizations of Meissner et al. [2012]. These simulations reveal the importance of two-dimensional factors (i.e., changes in sea level and rock type distribution) in the role of the weathering negative feedback mechanism on multi-millennial timescales.

Sources and characteristics of medium-scale traveling ionospheric disturbances observed by high-frequency radars in the North American sector

NASA Astrophysics Data System (ADS)

Frissell, N. A.; Baker, J. B. H.; Ruohoniemi, J. M.; Greenwald, R. A.; Gerrard, A. J.; Miller, E. S.; West, M. L.

2016-04-01

Medium-scale traveling ionospheric disturbances (MSTIDs) are wave-like ionospheric perturbations routinely observed by high-frequency radars. We focus on a class of MSTIDs observed during the winter daytime at high latitudes and midlatitudes. The source of these MSTIDs remains uncertain, with the two primary candidates being space weather and lower atmospheric processes. We surveyed observations from four high-latitude and six midlatitude Super Dual Auroral Radar Network radars in the North American sector from November to May 2012 to 2015. The MSTIDs observed have horizontal wavelengths between ˜150 and 650 km and horizontal velocities between ˜75 and 325 m s-1. In local fall and winter seasons the majority of MSTIDs propagated equatorward, with bearings ranging from ˜125° to 225° geographic azimuth. No clear correlation with space weather activity as parameterized by AE and SYM-H could be identified. Rather, MSTID observations were found to have a strong correlation with polar vortex dynamics on two timescales. First, a seasonal timescale follows the annual development and decay of the polar vortex. Second, a shorter 2-4 week timescale again corresponds to synoptic polar vortex variability, including stratospheric warmings. Additionally, statistical analysis shows that MSTIDs are more likely during periods of strong polar vortex. Direct comparison of the MSTID observations with stratospheric zonal winds suggests that a wind filtering mechanism may be responsible for the strong correlation. Collectively, these observations suggest that polar atmospheric processes, rather than space weather activity, are primarily responsible for controlling the occurrence of high-latitude and midlatitude winter daytime MSTIDs.

Sources and Characteristics of Medium Scale Traveling Ionospheric Disturbances Observed by High Frequency Radars in the North American Sector

NASA Astrophysics Data System (ADS)

Frissell, N. A.; Baker, J. B.; Ruohoniemi, J. M.; Greenwald, R. A.; Gerrard, A. J.; Miller, E. S.; West, M. L.

2016-12-01

Medium-scale traveling ionospheric disturbances (MSTIDs) are wave-like ionospheric perturbations routinely observed by high-frequency radars. We focus on a class of MSTIDs observed during the winter daytime at high latitudes and midlatitudes. The source of these MSTIDs remains uncertain, with the two primary candidates being space weather and lower atmospheric processes. We surveyed observations from four high-latitude and six midlatitude Super Dual Auroral Radar Network radars in the North American sector from November to May 2012 to 2015. The MSTIDs observed have horizontal wavelengths between 150 and 650 km and horizontal velocities between 75 and 325 m/s. In local fall and winter seasons the majority of MSTIDs propagated equatorward, with bearings ranging from 125° to 225° geographic azimuth. No clear correlation with space weather activity as parameterized by AE and SYM-H could be identified. Rather, MSTID observations were found to have a strong correlation with polar vortex dynamics on two timescales. First, a seasonal timescale follows the annual development and decay of the polar vortex. Second, a shorter 2-4 week timescale again corresponds to synoptic polar vortex variability, including stratospheric warmings. Additionally, statistical analysis shows that MSTIDs are more likely during periods of strong polar vortex. Direct comparison of the MSTID observations with stratospheric zonal winds suggests that a wind filtering mechanism may be responsible for the strong correlation. Collectively, these observations suggest that polar atmospheric processes, rather than space weather activity, are primarily responsible for controlling the occurrence of high-latitude and midlatitude winter daytime MSTIDs.

Multi-scale enhancement of climate prediction over land by increasing the model sensitivity to vegetation variability in EC-Earth

NASA Astrophysics Data System (ADS)

Alessandri, Andrea; Catalano, Franco; De Felice, Matteo; Van Den Hurk, Bart; Doblas Reyes, Francisco; Boussetta, Souhail; Balsamo, Gianpaolo; Miller, Paul

2016-04-01

The EC-Earth earth system model has been recently developed to include the dynamics of vegetation. In its original formulation, vegetation variability is simply operated by the Leaf Area Index (LAI), which affects climate basically by changing the vegetation physiological resistance to evapotranspiration. This coupling has been found to have only a weak effect on the surface climate modeled by EC-Earth. In reality, the effective sub-grid vegetation fractional coverage will vary seasonally and at interannual time-scales in response to leaf-canopy growth, phenology and senescence. Therefore it affects biophysical parameters such as the albedo, surface roughness and soil field capacity. To adequately represent this effect in EC-Earth, we included an exponential dependence of the vegetation cover on the LAI. By comparing two sets of simulations performed with and without the new variable fractional-coverage parameterization, spanning retrospective predictions at the decadal (5-years), seasonal and sub-seasonal time-scales, we show for the first time a significant multi-scale enhancement of vegetation impacts in climate simulation and prediction over land. Particularly large effects at multiple time scales are shown over boreal winter middle-to-high latitudes over Canada, West US, Eastern Europe, Russia and eastern Siberia due to the implemented time-varying shadowing effect by tree-vegetation on snow surfaces. Over Northern Hemisphere boreal forest regions the improved representation of vegetation cover tends to correct the winter warm biases, improves the climate change sensitivity, the decadal potential predictability as well as the skill of forecasts at seasonal and sub-seasonal time-scales. Significant improvements of the prediction of 2m temperature and rainfall are also shown over transitional land surface hot spots. Both the potential predictability at decadal time-scale and seasonal-forecasts skill are enhanced over Sahel, North American Great Plains, Nordeste Brazil and South East Asia, mainly related to improved performance in the surface evapotranspiration.

Multi-scale enhancement of climate prediction over land by increasing the model sensitivity to vegetation variability in EC-Earth

NASA Astrophysics Data System (ADS)

Alessandri, A.; Catalano, F.; De Felice, M.; van den Hurk, B.; Doblas-Reyes, F. J.; Boussetta, S.; Balsamo, G.; Miller, P. A.

2016-12-01

The European consortium earth system model (EC-Earth; http://www.ec-earth.org) has been recently developed to include the dynamics of vegetation. In its original formulation, vegetation variability is simply operated by the Leaf Area Index (LAI), which affects climate basically by changing the vegetation physiological resistance to evapotranspiration. This coupling has been found to have only a weak effect on the surface climate modeled by EC-Earth. In reality, the effective sub-grid vegetation fractional coverage will vary seasonally and at interannual time-scales in response to leaf-canopy growth, phenology and senescence. Therefore it affects biophysical parameters such as the albedo, surface roughness and soil field capacity. To adequately represent this effect in EC-Earth, we included an exponential dependence of the vegetation cover on the LAI. By comparing two sets of simulations performed with and without the new variable fractional-coverage parameterization, spanning from centennial (20th Century) simulations and retrospective predictions to the decadal (5-years), seasonal and weather time-scales, we show for the first time a significant multi-scale enhancement of vegetation impacts in climate simulation and prediction over land. Particularly large effects at multiple time scales are shown over boreal winter middle-to-high latitudes over Canada, West US, Eastern Europe, Russia and eastern Siberia due to the implemented time-varying shadowing effect by tree-vegetation on snow surfaces. Over Northern Hemisphere boreal forest regions the improved representation of vegetation cover tends to correct the winter warm biases, improves the climate change sensitivity, the decadal potential predictability as well as the skill of forecasts at seasonal and weather time-scales. Significant improvements of the prediction of 2m temperature and rainfall are also shown over transitional land surface hot spots. Both the potential predictability at decadal time-scale and seasonal-forecasts skill are enhanced over Sahel, North American Great Plains, Nordeste Brazil and South East Asia, mainly related to improved performance in the surface evapotranspiration.

Multi-scale enhancement of climate prediction over land by increasing the model sensitivity to vegetation variability in EC-Earth

NASA Astrophysics Data System (ADS)

Alessandri, Andrea; Catalano, Franco; De Felice, Matteo; Van Den Hurk, Bart; Doblas Reyes, Francisco; Boussetta, Souhail; Balsamo, Gianpaolo; Miller, Paul A.

2017-08-01

The EC-Earth earth system model has been recently developed to include the dynamics of vegetation. In its original formulation, vegetation variability is simply operated by the Leaf Area Index (LAI), which affects climate basically by changing the vegetation physiological resistance to evapotranspiration. This coupling has been found to have only a weak effect on the surface climate modeled by EC-Earth. In reality, the effective sub-grid vegetation fractional coverage will vary seasonally and at interannual time-scales in response to leaf-canopy growth, phenology and senescence. Therefore it affects biophysical parameters such as the albedo, surface roughness and soil field capacity. To adequately represent this effect in EC-Earth, we included an exponential dependence of the vegetation cover on the LAI. By comparing two sets of simulations performed with and without the new variable fractional-coverage parameterization, spanning from centennial (twentieth century) simulations and retrospective predictions to the decadal (5-years), seasonal and weather time-scales, we show for the first time a significant multi-scale enhancement of vegetation impacts in climate simulation and prediction over land. Particularly large effects at multiple time scales are shown over boreal winter middle-to-high latitudes over Canada, West US, Eastern Europe, Russia and eastern Siberia due to the implemented time-varying shadowing effect by tree-vegetation on snow surfaces. Over Northern Hemisphere boreal forest regions the improved representation of vegetation cover tends to correct the winter warm biases, improves the climate change sensitivity, the decadal potential predictability as well as the skill of forecasts at seasonal and weather time-scales. Significant improvements of the prediction of 2 m temperature and rainfall are also shown over transitional land surface hot spots. Both the potential predictability at decadal time-scale and seasonal-forecasts skill are enhanced over Sahel, North American Great Plains, Nordeste Brazil and South East Asia, mainly related to improved performance in the surface evapotranspiration.

Multi-scale enhancement of climate prediction over land by increasing the model sensitivity to vegetation variability in EC-Earth

NASA Astrophysics Data System (ADS)

Alessandri, Andrea; Catalano, Franco; De Felice, Matteo; Van Den Hurk, Bart; Doblas Reyes, Francisco; Boussetta, Souhail; Balsamo, Gianpaolo; Miller, Paul A.

2017-04-01

The EC-Earth earth system model has been recently developed to include the dynamics of vegetation. In its original formulation, vegetation variability is simply operated by the Leaf Area Index (LAI), which affects climate basically by changing the vegetation physiological resistance to evapotranspiration. This coupling has been found to have only a weak effect on the surface climate modeled by EC-Earth. In reality, the effective sub-grid vegetation fractional coverage will vary seasonally and at interannual time-scales in response to leaf-canopy growth, phenology and senescence. Therefore it affects biophysical parameters such as the albedo, surface roughness and soil field capacity. To adequately represent this effect in EC-Earth, we included an exponential dependence of the vegetation cover on the LAI. By comparing two sets of simulations performed with and without the new variable fractional-coverage parameterization, spanning from centennial (20th Century) simulations and retrospective predictions to the decadal (5-years), seasonal and weather time-scales, we show for the first time a significant multi-scale enhancement of vegetation impacts in climate simulation and prediction over land. Particularly large effects at multiple time scales are shown over boreal winter middle-to-high latitudes over Canada, West US, Eastern Europe, Russia and eastern Siberia due to the implemented time-varying shadowing effect by tree-vegetation on snow surfaces. Over Northern Hemisphere boreal forest regions the improved representation of vegetation cover tends to correct the winter warm biases, improves the climate change sensitivity, the decadal potential predictability as well as the skill of forecasts at seasonal and weather time-scales. Significant improvements of the prediction of 2m temperature and rainfall are also shown over transitional land surface hot spots. Both the potential predictability at decadal time-scale and seasonal-forecasts skill are enhanced over Sahel, North American Great Plains, Nordeste Brazil and South East Asia, mainly related to improved performance in the surface evapotranspiration.

Large-scale tropospheric transport in the Chemistry-Climate Model Initiative (CCMI) simulations

NASA Astrophysics Data System (ADS)

Orbe, Clara; Yang, Huang; Waugh, Darryn W.; Zeng, Guang; Morgenstern, Olaf; Kinnison, Douglas E.; Lamarque, Jean-Francois; Tilmes, Simone; Plummer, David A.; Scinocca, John F.; Josse, Beatrice; Marecal, Virginie; Jöckel, Patrick; Oman, Luke D.; Strahan, Susan E.; Deushi, Makoto; Tanaka, Taichu Y.; Yoshida, Kohei; Akiyoshi, Hideharu; Yamashita, Yousuke; Stenke, Andreas; Revell, Laura; Sukhodolov, Timofei; Rozanov, Eugene; Pitari, Giovanni; Visioni, Daniele; Stone, Kane A.; Schofield, Robyn; Banerjee, Antara

2018-05-01

Understanding and modeling the large-scale transport of trace gases and aerosols is important for interpreting past (and projecting future) changes in atmospheric composition. Here we show that there are large differences in the global-scale atmospheric transport properties among the models participating in the IGAC SPARC Chemistry-Climate Model Initiative (CCMI). Specifically, we find up to 40 % differences in the transport timescales connecting the Northern Hemisphere (NH) midlatitude surface to the Arctic and to Southern Hemisphere high latitudes, where the mean age ranges between 1.7 and 2.6 years. We show that these differences are related to large differences in vertical transport among the simulations, in particular to differences in parameterized convection over the oceans. While stronger convection over NH midlatitudes is associated with slower transport to the Arctic, stronger convection in the tropics and subtropics is associated with faster interhemispheric transport. We also show that the differences among simulations constrained with fields derived from the same reanalysis products are as large as (and in some cases larger than) the differences among free-running simulations, most likely due to larger differences in parameterized convection. Our results indicate that care must be taken when using simulations constrained with analyzed winds to interpret the influence of meteorology on tropospheric composition.

A Generalized Simple Formulation of Convective Adjustment ...

EPA Pesticide Factsheets

Convective adjustment timescale (τ) for cumulus clouds is one of the most influential parameters controlling parameterized convective precipitation in climate and weather simulation models at global and regional scales. Due to the complex nature of deep convection, a prescribed value or ad hoc representation of τ is used in most global and regional climate/weather models making it a tunable parameter and yet still resulting in uncertainties in convective precipitation simulations. In this work, a generalized simple formulation of τ for use in any convection parameterization for shallow and deep clouds is developed to reduce convective precipitation biases at different grid spacing. Unlike existing other methods, our new formulation can be used with field campaign measurements to estimate τ as demonstrated by using data from two different special field campaigns. Then, we implemented our formulation into a regional model (WRF) for testing and evaluation. Results indicate that our simple τ formulation can give realistic temporal and spatial variations of τ across continental U.S. as well as grid-scale and subgrid scale precipitation. We also found that as the grid spacing decreases (e.g., from 36 to 4-km grid spacing), grid-scale precipitation dominants over subgrid-scale precipitation. The generalized τ formulation works for various types of atmospheric conditions (e.g., continental clouds due to heating and large-scale forcing over la

Once more on the equilibrium-point hypothesis (lambda model) for motor control.

PubMed

Feldman, A G

1986-03-01

The equilibrium control hypothesis (lambda model) is considered with special reference to the following concepts: (a) the length-force invariant characteristic (IC) of the muscle together with central and reflex systems subserving its activity; (b) the tonic stretch reflex threshold (lambda) as an independent measure of central commands descending to alpha and gamma motoneurons; (c) the equilibrium point, defined in terms of lambda, IC and static load characteristics, which is associated with the notion that posture and movement are controlled by a single mechanism; and (d) the muscle activation area (a reformulation of the "size principle")--the area of kinematic and command variables in which a rank-ordered recruitment of motor units takes place. The model is used for the interpretation of various motor phenomena, particularly electromyographic patterns. The stretch reflex in the lambda model has no mechanism to follow-up a certain muscle length prescribed by central commands. Rather, its task is to bring the system to an equilibrium, load-dependent position. Another currently popular version defines the equilibrium point concept in terms of alpha motoneuron activity alone (the alpha model). Although the model imitates (as does the lambda model) spring-like properties of motor performance, it nevertheless is inconsistent with a substantial data base on intact motor control. An analysis of alpha models, including their treatment of motor performance in deafferented animals, reveals that they suffer from grave shortcomings. It is concluded that parameterization of the stretch reflex is a basis for intact motor control. Muscle deafferentation impairs this graceful mechanism though it does not remove the possibility of movement.

The water hexamer: three-body interactions, structures, energetics, and OH-stretch spectroscopy at finite temperature.

PubMed

Tainter, C J; Skinner, J L

2012-09-14

Using a newly developed and recently parameterized classical empirical simulation model for water that involves explicit three-body interactions, we determine the eleven most stable isomers of the water hexamer. We find that the lowest energy isomer is one of the cage structures, in agreement with far-IR and microwave experiments. The energy ordering for the binding energies is cage > glove > book > bag > chair > boat > chaise, and energies relative to the cage are in good agreement with CCSD(T) calculations. The three-body contributions to the cage, book, and chair are also in reasonable agreement with CCSD(T) results. The energy of each isomer results from a delicate balance involving the number of hydrogen bonds, the strain of these hydrogen bonds, and cooperative and anti-cooperative three-body interactions, whose contribution we can understand simply from the form of the three-body interactions in the simulation model. Oxygen-oxygen distances in the cage and book isomers are in good agreement with microwave experiments. Hydrogen-bond distances depend on both donor and acceptor, which can again be understood from the three-body model. Fully anharmonic OH-stretch spectra are calculated for these low-energy structures, and compared with shifted harmonic results from ab initio and density functional theory calculations. Replica-exchange molecular dynamics simulations were performed from 40 to 194 K, which show that the cage isomer has the lowest free energy from 0 to 70 K, and the book isomer has the lowest free energy from 70 to 194 K. OH-stretch spectra were calculated between 40 and 194 K, and results at 40, 63, and 79 K were compared to recent experiments, leading to re-assignment of the peaks in the experimental spectra. We calculate local OH-stretch cumulative spectral densities for different donor-acceptor types and compare to analogous results for liquid water.

Dynamic structural disorder in supported nanoscale catalysts

NASA Astrophysics Data System (ADS)

Rehr, J. J.; Vila, F. D.

2014-04-01

We investigate the origin and physical effects of "dynamic structural disorder" (DSD) in supported nano-scale catalysts. DSD refers to the intrinsic fluctuating, inhomogeneous structure of such nano-scale systems. In contrast to bulk materials, nano-scale systems exhibit substantial fluctuations in structure, charge, temperature, and other quantities, as well as large surface effects. The DSD is driven largely by the stochastic librational motion of the center of mass and fluxional bonding at the nanoparticle surface due to thermal coupling with the substrate. Our approach for calculating and understanding DSD is based on a combination of real-time density functional theory/molecular dynamics simulations, transient coupled-oscillator models, and statistical mechanics. This approach treats thermal and dynamic effects over multiple time-scales, and includes bond-stretching and -bending vibrations, and transient tethering to the substrate at longer ps time-scales. Potential effects on the catalytic properties of these clusters are briefly explored. Model calculations of molecule-cluster interactions and molecular dissociation reaction paths are presented in which the reactant molecules are adsorbed on the surface of dynamically sampled clusters. This model suggests that DSD can affect both the prefactors and distribution of energy barriers in reaction rates, and thus can significantly affect catalytic activity at the nano-scale.

Time-dependent changes in magmatic and hydrothermal activity at the Costa Rica Rift recorded by variations in oceanic crustal structure

NASA Astrophysics Data System (ADS)

Wilson, D. J.; Peirce, C.; Hobbs, R. W.; Gregory, E. P. M.; Zhang, L.

2016-12-01

Geophysical studies of crustal structure at a diverse range of ridges have provided evidence that the balance between spreading rate and magma supply determines whether spreading predominantly occurs by magmatic accretion of new oceanic crust or through tectonic stretching of the whole lithosphere. Asymmetric spreading, patterns of on- and off-axis volcanism, the evolution of oceanic core complexes and the distribution of hydrothermal systems all indicate that the process of spreading is not constant over geologically short timescales. The structure of the resulting crust reflects this complexity in origin. Studies along flow-lines across ridges spreading at intermediate rates suggest variations in topographic style and crustal structure have periodically occurred, controlled by the interplay between magmatic accretion and tectonic stretching, and coupled to the degree of hydrothermal activity. Seismic reflection images and tomographic models derived from wide-angle seismic data have enabled a detailed examination of the oceanic crust that formed at the fast-to-intermediate-spreading (36 mm yr-1) Costa Rica Rift over the last 6 Ma, to look for any temporal variation in basement topography, upper crust (layer 2) P-wave velocity/density structure and crustal thickness. Coincident marine gravity and magnetic data not only allow us to test the validity of the final velocity-density model but also review variability in half-spreading rate, respectively. Collectively our analyses allow us to investigate the timescale and cyclicity of crustal structure variations and, having determined the spreading rate over time, consider how this may reflect changes in magma supply and/or hydrothermal activity at the Costa Rica Rift, using borehole 504B as the ground-truth. This research is part of a major, interdisciplinary NERC-funded collaboration entitled: Oceanographic and Seismic Characterisation of heat dissipation and alteration by hydrothermal fluids at an Axial Ridge (OSCAR).

Temperature manipulation of neuronal dynamics in a forebrain motor control nucleus

PubMed Central

Mindlin, Gabriel B.

2017-01-01

Different neuronal types within brain motor areas contribute to the generation of complex motor behaviors. A widely studied songbird forebrain nucleus (HVC) has been recognized as fundamental in shaping the precise timing characteristics of birdsong. This is based, among other evidence, on the stretching and the “breaking” of song structure when HVC is cooled. However, little is known about the temperature effects that take place in its neurons. To address this, we investigated the dynamics of HVC both experimentally and computationally. We developed a technique where simultaneous electrophysiological recordings were performed during temperature manipulation of HVC. We recorded spontaneous activity and found three effects: widening of the spike shape, decrease of the firing rate and change in the interspike interval distribution. All these effects could be explained with a detailed conductance based model of all the neurons present in HVC. Temperature dependence of the ionic channel time constants explained the first effect, while the second was based in the changes of the maximal conductance using single synaptic excitatory inputs. The last phenomenon, only emerged after introducing a more realistic synaptic input to the inhibitory interneurons. Two timescales were present in the interspike distributions. The behavior of one timescale was reproduced with different input balances received form the excitatory neurons, whereas the other, which disappears with cooling, could not be found assuming poissonian synaptic inputs. Furthermore, the computational model shows that the bursting of the excitatory neurons arises naturally at normal brain temperature and that they have an intrinsic delay at low temperatures. The same effect occurs at single synapses, which may explain song stretching. These findings shed light on the temperature dependence of neuronal dynamics and present a comprehensive framework to study neuronal connectivity. This study, which is based on intrinsic neuronal characteristics, may help to understand emergent behavioral changes. PMID:28829769

Recent topographic evolution and erosion of the deglaciated Washington Cascades inferred from a stochastic landscape evolution model

NASA Astrophysics Data System (ADS)

Moon, S.; Shelef, E.; Hilley, G. E.

2013-12-01

The Washington Cascades is currently in topographic and erosional disequilibrium after deglaciation occurred around 11- 17 ka ago. The topography still shows the features inherited from prior alpine glacial processes (e.g., cirques, steep side-valleys, and flat valley bottoms), though postglacial processes are currently denuding this landscape. Our previous study in this area calculated the thousand-year-timescale denudation rates using cosmogenic 10Be concentration (CRN-denudation rates), and showed that they were ~ four times higher than million-year-timescale uplift rates. In addition, the spatial distribution of denudation rates showed a good correlation with a factor-of-ten variation in precipitation. We interpreted this correlation as reflecting the sensitivity of landslide triggering in over-steepened deglaciated topography to precipitation, which produced high denudation rates in wet areas that experienced frequent landsliding. We explored this interpretation using a model of postglacial surface processes that predicts the evolution of the topography and denudation rates within the deglaciated Washington Cascades. Specifically, we used the model to understand the controls on and timescales of landscape response to changes in the surface process regime after deglaciation. The postglacial adjustment of this landscape is modeled using a geomorphic-transport-law-based numerical model that includes processes of river incision, hillslope diffusion, and stochastic landslides. The surface lowering due to landslides is parameterized using a physically-based slope stability model coupled to a stochastic model of the generation of landslides. The model parameters of river incision and stochastic landslides are calibrated based on the rates and distribution of thousand-year-timescale denudation rates measured from cosmogenic 10Be isotopes. The probability distribution of model parameters required to fit the observed denudation rates shows comparable ranges from previous studies in similar rock types and climatic conditions. The calibrated parameters suggest that the dominant sediment source of river sediments originates from stochastic landslides. The magnitude of landslide denudation rates is determined by failure density (similar to landslide frequency), while their spatial distribution is largely controlled by precipitation and slope angles. Simulation results show that denudation rates decay over time and take approximately 130-180 ka to reach steady-state rates. This response timescale is longer than glacial/interglacial cycles, suggesting that frequent climatic perturbations during the Quaternary may prevent these types of landscapes from reaching a dynamic equilibrium with postglacial processes.

Simultaneous event-specific estimates of transport, loss, and source rates for relativistic outer radiation belt electrons: Event-Specific 1-D Modeling

DOE PAGES

Schiller, Q.; Tu, W.; Ali, A. F.; ...

2017-03-11

The most significant unknown regarding relativistic electrons in Earth’s outer Van Allen radiation belt is the relative contribution of loss, transport, and acceleration processes within the inner magnetosphere. Detangling each individual process is critical to improve the understanding of radiation belt dynamics, but determining a single component is challenging due to sparse measurements in diverse spatial and temporal regimes. However, there are currently an unprecedented number of spacecraft taking measurements that sample different regions of the inner magnetosphere. With the increasing number of varied observational platforms, system dynamics can begin to be unraveled. In this work, we employ in-situ measurementsmore » during the 13-14 January 2013 enhancement event to isolate transport, loss, and source dynamics in a one dimensional radial diffusion model. We then validate the results by comparing them to Van Allen Probes and THEMIS observations, indicating that the three terms have been accurately and individually quantified for the event. Finally, a direct comparison is performed between the model containing event-specific terms and various models containing terms parameterized by geomagnetic index. Models using a simple 3/Kp loss timescale show deviation from the event specific model of nearly two orders of magnitude within 72 hours of the enhancement event. However, models using alternative loss timescales closely resemble the event specific model.« less

Simultaneous event-specific estimates of transport, loss, and source rates for relativistic outer radiation belt electrons: Event-Specific 1-D Modeling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schiller, Q.; Tu, W.; Ali, A. F.

The most significant unknown regarding relativistic electrons in Earth’s outer Van Allen radiation belt is the relative contribution of loss, transport, and acceleration processes within the inner magnetosphere. Detangling each individual process is critical to improve the understanding of radiation belt dynamics, but determining a single component is challenging due to sparse measurements in diverse spatial and temporal regimes. However, there are currently an unprecedented number of spacecraft taking measurements that sample different regions of the inner magnetosphere. With the increasing number of varied observational platforms, system dynamics can begin to be unraveled. In this work, we employ in-situ measurementsmore » during the 13-14 January 2013 enhancement event to isolate transport, loss, and source dynamics in a one dimensional radial diffusion model. We then validate the results by comparing them to Van Allen Probes and THEMIS observations, indicating that the three terms have been accurately and individually quantified for the event. Finally, a direct comparison is performed between the model containing event-specific terms and various models containing terms parameterized by geomagnetic index. Models using a simple 3/Kp loss timescale show deviation from the event specific model of nearly two orders of magnitude within 72 hours of the enhancement event. However, models using alternative loss timescales closely resemble the event specific model.« less

Will high-resolution global ocean models benefit coupled predictions on short-range to climate timescales?

NASA Astrophysics Data System (ADS)

Hewitt, Helene T.; Bell, Michael J.; Chassignet, Eric P.; Czaja, Arnaud; Ferreira, David; Griffies, Stephen M.; Hyder, Pat; McClean, Julie L.; New, Adrian L.; Roberts, Malcolm J.

2017-12-01

As the importance of the ocean in the weather and climate system is increasingly recognised, operational systems are now moving towards coupled prediction not only for seasonal to climate timescales but also for short-range forecasts. A three-way tension exists between the allocation of computing resources to refine model resolution, the expansion of model complexity/capability, and the increase of ensemble size. Here we review evidence for the benefits of increased ocean resolution in global coupled models, where the ocean component explicitly represents transient mesoscale eddies and narrow boundary currents. We consider lessons learned from forced ocean/sea-ice simulations; from studies concerning the SST resolution required to impact atmospheric simulations; and from coupled predictions. Impacts of the mesoscale ocean in western boundary current regions on the large-scale atmospheric state have been identified. Understanding of air-sea feedback in western boundary currents is modifying our view of the dynamics in these key regions. It remains unclear whether variability associated with open ocean mesoscale eddies is equally important to the large-scale atmospheric state. We include a discussion of what processes can presently be parameterised in coupled models with coarse resolution non-eddying ocean models, and where parameterizations may fall short. We discuss the benefits of resolution and identify gaps in the current literature that leave important questions unanswered.

Easy Volcanic Aerosol (EVA v1.0): an idealized forcing generator for climate simulations

NASA Astrophysics Data System (ADS)

Toohey, Matthew; Stevens, Bjorn; Schmidt, Hauke; Timmreck, Claudia

2016-11-01

Stratospheric sulfate aerosols from volcanic eruptions have a significant impact on the Earth's climate. To include the effects of volcanic eruptions in climate model simulations, the Easy Volcanic Aerosol (EVA) forcing generator provides stratospheric aerosol optical properties as a function of time, latitude, height, and wavelength for a given input list of volcanic eruption attributes. EVA is based on a parameterized three-box model of stratospheric transport and simple scaling relationships used to derive mid-visible (550 nm) aerosol optical depth and aerosol effective radius from stratospheric sulfate mass. Precalculated look-up tables computed from Mie theory are used to produce wavelength-dependent aerosol extinction, single scattering albedo, and scattering asymmetry factor values. The structural form of EVA and the tuning of its parameters are chosen to produce best agreement with the satellite-based reconstruction of stratospheric aerosol properties following the 1991 Pinatubo eruption, and with prior millennial-timescale forcing reconstructions, including the 1815 eruption of Tambora. EVA can be used to produce volcanic forcing for climate models which is based on recent observations and physical understanding but internally self-consistent over any timescale of choice. In addition, EVA is constructed so as to allow for easy modification of different aspects of aerosol properties, in order to be used in model experiments to help advance understanding of what aspects of the volcanic aerosol are important for the climate system.

Photometric properties of intermediate-redshift Type Ia supernovae observed by the Sloan Digital Sky Survey-II Supernova Survey

DOE PAGES

Takanashi, N.; Doi, M.; Yasuda, N.; ...

2016-12-06

We have analyzed multi-band light curves of 328 intermediate redshift (0.05 <= z < 0.24) type Ia supernovae (SNe Ia) observed by the Sloan Digital Sky Survey-II Supernova Survey (SDSS-II SN Survey). The multi-band light curves were parameterized by using the Multi-band Stretch Method, which can simply parameterize light curve shapes and peak brightness without dust extinction models. We found that most of the SNe Ia which appeared in red host galaxies (u - r > 2.5) don't have a broad light curve width and the SNe Ia which appeared in blue host galaxies (u - r < 2.0) havemore » a variety of light curve widths. The Kolmogorov-Smirnov test shows that the colour distribution of SNe Ia appeared in red / blue host galaxies is different (significance level of 99.9%). We also investigate the extinction law of host galaxy dust. As a result, we find the value of Rv derived from SNe Ia with medium light curve width is consistent with the standard Galactic value. On the other hand, the value of Rv derived from SNe Ia that appeared in red host galaxies becomes significantly smaller. Furthermore, these results indicate that there may be two types of SNe Ia with different intrinsic colours, and they are obscured by host galaxy dust with two different properties.« less

Photometric properties of intermediate-redshift Type Ia supernovae observed by the Sloan Digital Sky Survey-II Supernova Survey

DOE Office of Scientific and Technical Information (OSTI.GOV)

Takanashi, N.; Doi, M.; Yasuda, N.

We have analyzed multi-band light curves of 328 intermediate redshift (0.05 <= z < 0.24) type Ia supernovae (SNe Ia) observed by the Sloan Digital Sky Survey-II Supernova Survey (SDSS-II SN Survey). The multi-band light curves were parameterized by using the Multi-band Stretch Method, which can simply parameterize light curve shapes and peak brightness without dust extinction models. We found that most of the SNe Ia which appeared in red host galaxies (u - r > 2.5) don't have a broad light curve width and the SNe Ia which appeared in blue host galaxies (u - r < 2.0) havemore » a variety of light curve widths. The Kolmogorov-Smirnov test shows that the colour distribution of SNe Ia appeared in red / blue host galaxies is different (significance level of 99.9%). We also investigate the extinction law of host galaxy dust. As a result, we find the value of Rv derived from SNe Ia with medium light curve width is consistent with the standard Galactic value. On the other hand, the value of Rv derived from SNe Ia that appeared in red host galaxies becomes significantly smaller. Furthermore, these results indicate that there may be two types of SNe Ia with different intrinsic colours, and they are obscured by host galaxy dust with two different properties.« less

O-H anharmonic vibrational motions in Cl(-)···(CH3OH)(1-2) ionic clusters. Combined IRPD experiments and AIMD simulations.

PubMed

Beck, Jordan P; Cimas, Alvaro; Lisy, James M; Gaigeot, Marie-Pierre

2014-02-05

The structures of Cl(-)-(Methanol)1,2 clusters have been unraveled combining Infrared Predissociation (IR-PD) experiments and DFT-based molecular dynamics simulations (DFT-MD) at 100 K. The dynamical IR spectra extracted from DFT-MD provide the initial 600 cm(-1) large anharmonic red-shift of the O-H stretch from uncomplexed methanol (3682 cm(-1)) to Cl(-)-(Methanol)1 complex (3085 cm(-1)) as observed in the IR-PD experiment, as well as the subtle supplementary blue- and red-shifts of the O-H stretch in Cl(-)-(Methanol)2 depending on the structure. The anharmonic vibrational calculations remarkably provide the 100 cm(-1) O-H blue-shift when the two methanol molecules are simultaneously organized in the anion first hydration shell (conformer 2A), while they provide the 240 cm(-1) O-H red-shift when the second methanol is in the second hydration shell of Cl(-) (conformer 2B). RRKM calculations have also shown that 2A/2B conformers interconvert on a nanosecond time-scale at the estimated 100 K temperature of the clusters formed by evaporative cooling of argon prior to the IR-PD process. Copyright © 2013 Elsevier B.V. All rights reserved.

Unravelling the mechanisms of vibrational relaxation in solution.

PubMed

Grubb, Michael P; Coulter, Philip M; Marroux, Hugo J B; Orr-Ewing, Andrew J; Ashfold, Michael N R

2017-04-01

We present a systematic study of the mode-specific vibrational relaxation of NO 2 in six weakly-interacting solvents (perfluorohexane, perfluoromethylcyclohexane, perfluorodecalin, carbon tetrachloride, chloroform, and d-chloroform), chosen to elucidate the dominant energy transfer mechanisms in the solution phase. Broadband transient vibrational absorption spectroscopy has allowed us to extract quantum state-resolved relaxation dynamics of the two distinct NO 2 fragments produced from the 340 nm photolysis of N 2 O 4 → NO 2 (X) + NO 2 (A) and their separate paths to thermal equilibrium. Distinct relaxation pathways are observed for the NO 2 bending and stretching modes, even at energies as high as 7000 cm -1 above the potential minimum. Vibrational energy transfer is governed by different interaction mechanisms in the various solvent environments, and proceeds with timescales ranging from 20-1100 ps. NO 2 relaxation rates in the perfluorocarbon solvents are identical despite differences in acceptor mode state densities, infrared absorption cross sections, and local solvent structure. Vibrational energy is shown to be transferred to non-vibrational solvent degrees of freedom (V-T) through impulsive collisions with the perfluorocarbon molecules. Conversely, NO 2 relaxation in chlorinated solvents is reliant on vibrational resonances (V-V) while V-T energy transfer is inefficient and thermal excitation of the surrounding solvent molecules inhibits faster vibrational relaxation through direct complexation. Intramolecular vibrational redistribution allows the symmetric stretch of NO 2 to act as a gateway for antisymmetric stretch energy to exit the molecule. This study establishes an unprecedented level of detail for the cooling dynamics of a solvated small molecule, and provides a benchmark system for future theoretical studies of vibrational relaxation processes in solution.

Control of Vocal and Respiratory Patterns in Birdsong: Dissection of Forebrain and Brainstem Mechanisms Using Temperature

PubMed Central

Fee, Michale S.

2011-01-01

Learned motor behaviors require descending forebrain control to be coordinated with midbrain and brainstem motor systems. In songbirds, such as the zebra finch, regular breathing is controlled by brainstem centers, but when the adult songbird begins to sing, its breathing becomes tightly coordinated with forebrain-controlled vocalizations. The periods of silence (gaps) between song syllables are typically filled with brief breaths, allowing the bird to sing uninterrupted for many seconds. While substantial progress has been made in identifying the brain areas and pathways involved in vocal and respiratory control, it is not understood how respiratory and vocal control is coordinated by forebrain motor circuits. Here we combine a recently developed technique for localized brain cooling, together with recordings of thoracic air sac pressure, to examine the role of cortical premotor nucleus HVC (proper name) in respiratory-vocal coordination. We found that HVC cooling, in addition to slowing all song timescales as previously reported, also increased the duration of expiratory pulses (EPs) and inspiratory pulses (IPs). Expiratory pulses, like song syllables, were stretched uniformly by HVC cooling, but most inspiratory pulses exhibited non-uniform stretch of pressure waveform such that the majority of stretch occurred late in the IP. Indeed, some IPs appeared to change duration by the earlier or later truncation of an underlying inspiratory event. These findings are consistent with the idea that during singing the temporal structure of EPs is under the direct control of forebrain circuits, whereas that of IPs can be strongly influenced by circuits downstream of HVC, likely in the brainstem. An analysis of the temporal jitter of respiratory and vocal structure suggests that IPs may be initiated by HVC at the end of each syllable and terminated by HVC immediately before the onset of the next syllable. PMID:21980466

Implementation and calibration of a stochastic multicloud convective parameterization in the NCEP Climate Forecast System (CFSv2)

NASA Astrophysics Data System (ADS)

Goswami, B. B.; Khouider, B.; Phani, R.; Mukhopadhyay, P.; Majda, A. J.

2017-07-01

A comparative analysis of fourteen 5 year long climate simulations produced by the National Centers for Environmental Predictions (NCEP) Climate Forecast System version 2 (CFSv2), in which a stochastic multicloud (SMCM) cumulus parameterization is implemented, is presented here. These 5 year runs are made with different sets of parameters in order to figure out the best model configuration based on a suite of state-of-the-art metrics. This analysis is also a systematic attempt to understand the model sensitivity to the SMCM parameters. The model is found to be resilient to minor changes in the parameters used implying robustness of the SMCM formulation. The model is found to be most sensitive to the midtropospheric dryness parameter (MTD) and to the stratiform cloud decay timescale (τ30). MTD is more effective in controlling the global mean precipitation and its distribution while τ30 has more effect on the organization of convection as noticed in the simulation of the Madden-Julian oscillation (MJO). This is consistent with the fact that in the SMCM formulation, midtropospheric humidity controls the deepening of convection and stratiform clouds control the backward tilt of tropospheric heating and the strength of unsaturated downdrafts which cool and dry the boundary layer and trigger the propagation of organized convection. Many other studies have also found midtropospheric humidity to be a key factor in the capacity of a global climate model to simulate organized convection on the synoptic and intraseasonal scales.

The Distribution and Magnitude of Glacial Erosion on 103-year Timescales at Engabreen, Norway

NASA Astrophysics Data System (ADS)

Rand, C.; Goehring, B. M.

2017-12-01

We derive the magnitudes of glacial erosion integrated over 103-year timescales across a transect transverse to the direction of ice flow at Engabreen, Norway. Understanding the distribution of glacial erosion is important for several reasons, including sediment budgeting to fjord environments, development of robust landscape evolution models, and if a better understanding between erosion and ice-bed interface properties (e.g., sliding rate, basal water pressure) can be developed, we can use records of glacial erosion to infer glaciological properties that can ultimately benefit models of past and future glaciers. With few exceptions, measurements of glacial erosion are limited to the historical past and even then are rare owing to the difficulty of accessing the glacier bed. One method proven useful in estimating glacial erosion on 103-year timescales is to measure the remaining concentrations of cosmogenic nuclides that accumulate in exposed bedrock during periods of retracted glacier extent and are removed by glacial erosion and radioactive decay during ice cover. Here we will present measurements of 14C and 10Be measured in proglacial bedrock from Engabreen. Our transects are ca. 600 and 400 meters in front of the modern ice front, and based on historical imagery, was ice covered until the recent past. Initial 10Be results show an increase in concentrations of nearly an order of magnitude from the samples near the center of the glacial trough to those on the lateral margin, consistent with conceptual models of glacial erosion parameterized in terms of sliding velocity. Naïve exposure ages that assume no subglacial erosion range from 0.22 - 9.04 ka. More importantly, we can estimate erosion depths by assuming zero erosion of the highest concentration sample along the two transects and calculate the amount of material removed to yield the lower concentrations elsewhere along the two transects. Results indicate minimum erosion depths of 1-183 cm for most ice proximal transect and 7-56 cm for the more distal one.

Atmospheric turbulence above coastal waters: Determination of stability classes and a simple model for offshore flow including advection and dissipation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Erbrink, H.J.; Scholten, D.A.

1995-10-01

Atmospheric turbulence intensities and timescales have been measured for one year and modeled in a shoreline environment. Measurements were carried out at two sites, on both sides of the shoreline, about 10 km from the beach. The frequency distribution of Pasquill stability classes [determined using the COPS (calculation of Pasquill stability) method by analyzing wind fluctuations] was compared with similar observations at the land site. A shift to the more stable classes is observed. Moreover, a large shift to the stable classes was shown at the overwater site for the COPS method in comparison to the Hanna et al. andmore » Hsu method, which is based upon z/L values, originating from sea-air temperature differences. The observed values of the lateral wind fluctuations {sigma}{sub {nu}} and stability classes for the dataset could not be adequately described in terms of local parameters such as Obukhov length L and friction velocity u. Therefore, a simple model, which explicitly considered advection and dissipation in the turbulent kinetic energy equation, was formulated for the calculation of turbulence intensity at sea for offshore wind flows; dissipation is assumed to scale well with {sigma}{sub {nu}}{sup 3}/uT{sub {ell}}. Using this model, observed {sigma}{sub {nu}} values were explained remarkably well. It is concluded that atmospheric turbulence intensity above sea in the vicinity of the shoreline is strongly influenced by horizontal gradients and cannot be described successfully only in terms of local parameterization. The calculated values of the Eulerian timescale correlate quite well with measured values of {sigma}{sub {nu}}/u at both sites. However, values of the timescale at sea were larger; this may be caused by differences in roughness lengths between land and sea. 43 refs., 11 figs., 3 tabs.« less

Stochasticity of convection in Giga-LES data

NASA Astrophysics Data System (ADS)

De La Chevrotière, Michèle; Khouider, Boualem; Majda, Andrew J.

2016-09-01

The poor representation of tropical convection in general circulation models (GCMs) is believed to be responsible for much of the uncertainty in the predictions of weather and climate in the tropics. The stochastic multicloud model (SMCM) was recently developed by Khouider et al. (Commun Math Sci 8(1):187-216, 2010) to represent the missing variability in GCMs due to unresolved features of organized tropical convection. The SMCM is based on three cloud types (congestus, deep and stratiform), and transitions between these cloud types are formalized in terms of probability rules that are functions of the large-scale environment convective state and a set of seven arbitrary cloud timescale parameters. Here, a statistical inference method based on the Bayesian paradigm is applied to estimate these key cloud timescales from the Giga-LES dataset, a 24-h large-eddy simulation (LES) of deep tropical convection (Khairoutdinov et al. in J Adv Model Earth Syst 1(12), 2009) over a domain comparable to a GCM gridbox. A sequential learning strategy is used where the Giga-LES domain is partitioned into a few subdomains, and atmospheric time series obtained on each subdomain are used to train the Bayesian procedure incrementally. Convergence of the marginal posterior densities for all seven parameters is demonstrated for two different grid partitions, and sensitivity tests to other model parameters are also presented. A single column model simulation using the SMCM parameterization with the Giga-LES inferred parameters reproduces many important statistical features of the Giga-LES run, without any further tuning. In particular it exhibits intermittent dynamical behavior in both the stochastic cloud fractions and the large scale dynamics, with periods of dry phases followed by a coherent sequence of congestus, deep, and stratiform convection, varying on timescales of a few hours consistent with the Giga-LES time series. The chaotic variations of the cloud area fractions were captured fairly well both qualitatively and quantitatively demonstrating the stochastic nature of convection in the Giga-LES simulation.

What Mantle Processes Determine Isotopic

NASA Astrophysics Data System (ADS)

Tackley, P. J.; Xie, S.

2003-12-01

Isotopic measurements on Mid Ocean Ridge Basalts and Ocean Island Basalts indicate effective `ages' (from e.g., U-Pb or Sm-Nd systems) in the range 1-2 billion years- much less than the age of the Earth, even though melting should have been much more vigorous early on and skewed the mean time since melting to older values. This relatively young `age' has generally been explained in terms of stretching of heterogeneities by mantle convection, which might reduce them to dimensions too small to be individually distinguishable in short timescales of less than 1 Gyr. On the other hand, published numerical models that use tracers to track differentiated material (Christensen and Hofmann, 1994, Davies, 2002) suggest that Earth-like `ages' can be obtained without taking stretching-induced erasure of tracer signatures into account, although this might effectively happen if the lengthscale for sampling the isotope systems was large enough. In those models, the only explicit mechanism for resetting isotope systems was re-melting, but for this to explain the isotopic ages observed for basalts, the global rate of melting in the recent past would have had to be very much higher than present-day values. To investigate stretching vs. re-melting we have conducted numerical experiments of a cooling mantle with plate tectonics, differentiation and evolution of important isotopic systems. The time of last melting and the total strain is tracked on each tracer (in addition to isotopic information). The results confirm that a model matching today's crustal production rate and with a reasonable secular cooling history generates `ages' that are substantially larger than those observed, with the extent of crustal settling above the CMB making some difference but not enough. The effect of sampling lengthscale on observed `age' is also tested and found to be insufficient to explain the data. Thus, these results reaffirm the importance of stretching as a key mechanism for effectively deleting older heterogeneities. From analysis of strain vs. age and matching of the observed ages, it is estimated that erasure of heterogeneities occurs at strains of 103-104, somewhat larger than has often been assumed.

Water Interfaces, Solvation, and Spectroscopy

NASA Astrophysics Data System (ADS)

Geissler, Phillip L.

2013-04-01

Liquid water consistently expands our appreciation of the rich statistical mechanics that can emerge from simple molecular constituents. Here I review several interrelated areas of recent work on aqueous systems that aim to explore and explain this richness by revealing molecular arrangements, their thermodynamic origins, and the timescales on which they change. Vibrational spectroscopy of OH stretching features prominently in these discussions, with an emphasis on efforts to establish connections between spectroscopic signals and statistics of intermolecular structure. For bulk solutions, the results of these efforts largely verify and enrich existing physical pictures of hydrogen-bond network connectivity, dynamics, and response. For water at interfaces, such pictures are still emerging. As an important example I discuss the solvation of small ions at the air-water interface, whose surface propensities challenge a basic understanding of how aqueous fluctuations accommodate solutes in heterogeneous environments.

CO Diffusion into Amorphous H2O Ices

NASA Astrophysics Data System (ADS)

Lauck, Trish; Karssemeijer, Leendertjan; Shulenberger, Katherine; Rajappan, Mahesh; Öberg, Karin I.; Cuppen, Herma M.

2015-03-01

The mobility of atoms, molecules, and radicals in icy grain mantles regulates ice restructuring, desorption, and chemistry in astrophysical environments. Interstellar ices are dominated by H2O, and diffusion on external and internal (pore) surfaces of H2O-rich ices is therefore a key process to constrain. This study aims to quantify the diffusion kinetics and barrier of the abundant ice constituent CO into H2O-dominated ices at low temperatures (15-23 K), by measuring the mixing rate of initially layered H2O(:CO2)/CO ices. The mixed fraction of CO as a function of time is determined by monitoring the shape of the infrared CO stretching band. Mixing is observed at all investigated temperatures on minute timescales and can be ascribed to CO diffusion in H2O ice pores. The diffusion coefficient and final mixed fraction depend on ice temperature, porosity, thickness, and composition. The experiments are analyzed by applying Fick’s diffusion equation under the assumption that mixing is due to CO diffusion into an immobile H2O ice. The extracted energy barrier for CO diffusion into amorphous H2O ice is ˜160 K. This is effectively a surface diffusion barrier. The derived barrier is low compared to current surface diffusion barriers in use in astrochemical models. Its adoption may significantly change the expected timescales for different ice processes in interstellar environments.

Turbulent mixing within the Kuroshio in the Tokara Strait

NASA Astrophysics Data System (ADS)

Tsutsumi, Eisuke; Matsuno, Takeshi; Lien, Ren-Chieh; Nakamura, Hirohiko; Senjyu, Tomoharu; Guo, Xinyu

2017-09-01

Turbulent mixing and background current were observed using a microstructure profiler and acoustic Doppler current profilers in the Tokara Strait, where many seamounts and small islands exist within the route of the Kuroshio in the East China Sea. Vertical structure and water properties of the Kuroshio were greatly modified downstream from shallow seamounts. In the lee of a seamount crest at 200 m depth, the modification made the flow tend to shear instability, and the vertical eddy diffusivity is enhanced by nearly 100 times that of the upstream site, to Kρ ˜ O(10-3)-O(10-2) m2 s-1. A one-dimensional diffusion model using the observed eddy diffusivity reproduced the observed downstream evolution of the temperature-salinity profile. However, the estimated diffusion time-scale is at least 10 times longer than the observed advection time-scale. This suggests that the eddy diffusivity reaches to O(10-1) m2 s-1 in the vicinity of the seamount. At a site away from the abrupt topography, eddy diffusivity was also elevated to O(10-3) m2 s-1, and was associated with shear instability presumably induced by the Kuroshio shear and near-inertial internal-wave shear. Our study suggests that a better prediction of current, water-mass properties, and nutrients within the Kuroshio requires accurate understanding and parameterization of flow-topography interaction such as internal hydraulics, the associated internal-wave processes, and turbulent mixing processes.

Scales of convective activity in the MJO (Invited)

NASA Astrophysics Data System (ADS)

Houze, R.

2013-12-01

One of the results of the Dynamics of the Madden-Julian Oscillation (MJO) field experiment (DYNAMO) is the realization that an active period of the MJO is not a continuous stretch of time in which convection and rainfall are occurring. Rather, an active MJO period, as determined by standard statistical treatments of the wind and satellite data such as that of Wheeler and Hendon (2004), has periods of highly suppressed conditions interspersed with bursts or episodes of deep convection and rainfall. At a given location, an MJO cycle is of the order of 30-60 days. The active half of a cycle is then about 2-4 weeks. DYNAMO data show that within this multi-week period rain falls in intermittent bursts of deep convection at intervals of 2-6 days, with each burst lasting 1-2 days. The time between bursts is highly suppressed, such that the convective cloud population consists of shallow non-precipitating cumulus. This intermediate burst timescale is neither the MJO timescale nor the timescale of an individual convective cloud. The modulation on the 2-6 day timescale was related to various types of higher frequency equatorial waves (especially, inertio-gravity waves and easterly waves). The largest individual convective cloud element in the MJO environment is the mesoscale convective system (MCS), which lasts about a half day, much shorter than the time period of the wave-modulated bursts. The intermediate scale bursts reflect an evolution of the cloud population. Numerous individual cloud systems undergo their lifecycles within the envelope of the wave-controlled time period of a few days. At a given site, such as the principal island site of Addu Atoll in DYNAMO, radar observations show that in an intermediate timescale episode the convective ensemble goes through a systematic series of stages characterized by differing proportions of elements of different sizes and intensities. The first stage is a population of shallow non-precipitating cumulus, followed by an ensemble of clouds containing some deeper convective elements. At the time of maximum rain during the episode, the population contains growing mesoscale systems. As the rain episode declines the population contains a substantial number of MCSs with broad stratiform regions. Thus, at least three scales are critical in the active periods of an MJO: the MJO scale, the equatorial wave scale of 2-6 days, and the scale of individual clouds, the largest of which are MCSs. This presentation will document the large-scale environment conditions on each of these scales, the population characteristics of the convection during the wave-modulated bursts, and of the individual cloud systems themselves.

The Annual Glaciohydrology Cycle in the Ablation Zone of the Greenland Ice Sheet: Part 1. Hydrology Model

NASA Technical Reports Server (NTRS)

Colgan, William; Rajaram, Harihar; Anderson, Robert; Steffen. Konrad; Phillips, Thomas; Zwally, H. Jay; Abdalati, Waleed

2012-01-01

We apply a novel one-dimensional glacier hydrology model that calculates hydraulic head to the tidewater-terminating Sermeq Avannarleq flowline of the Greenland ice sheet. Within a plausible parameter space, the model achieves a quasi-steady-state annual cycle in which hydraulic head oscillates close to flotation throughout the ablation zone. Flotation is briefly achieved during the summer melt season along a approx.17 km stretch of the approx.50 km of flowline within the ablation zone. Beneath the majority of the flowline, subglacial conduit storage closes (i.e. obtains minimum radius) during the winter and opens (i.e. obtains maximum radius) during the summer. Along certain stretches of the flowline, the model predicts that subglacial conduit storage remains open throughout the year. A calculated mean glacier water residence time of approx.2.2 years implies that significant amounts of water are stored in the glacier throughout the year. We interpret this residence time as being indicative of the timescale over which the glacier hydrologic system is capable of adjusting to external surface meltwater forcings. Based on in situ ice velocity observations, we suggest that the summer speed-up event generally corresponds to conditions of increasing hydraulic head during inefficient subglacial drainage. Conversely, the slowdown during fall generally corresponds to conditions of decreasing hydraulic head during efficient subglacial drainage.

The Subglacial Access and Fast Ice Research Experiment - SAFIRE - on Store Glacier, West Greenland

NASA Astrophysics Data System (ADS)

Christoffersen, P.; Hubbard, B. P.; Doyle, S. H.; Young, T. J.; Hofstede, C. M.; Bougamont, M. H.; Todd, J.; Toberg, N.; Nicholls, K. W.; Box, J.; Walter, J. I.; Hubbard, A.

2015-12-01

Marine-terminating outlet glaciers drain 90 percent of the Greenland Ice Sheet and are responsible for about half of the ice sheet's net annual mass loss, which currently raises global sea level by 1 mm per year. The basal controls on these fast-flowing glaciers are, however, poorly understood, with the implication that numerical ice sheet models needed to predict future dynamic ice loss from Greenland relies on uncertain and often untested basal parameterizations. The Subglacial Access and Fast Ice Research Experiment - SAFIRE - is addressing this paucity of observational constraints by drilling to the bed of Store Glacier, a fast-flowing outlet glacier terminating in Uummannaq Fjord, West Greenland. In 2014, we gained access to the bed in four boreholes drilled to depths of 603-616 m near the center of the glacier, 30 km inland from the calving terminus where ice flows at a rate of 700 m/year. A seismic survey showed the glacier bed to consist of water-saturated, soft sediment. The water level in all four boreholes nevertheless dropped rapidly to 80 m below the ice surface when the drill connected with a basal water system, indicating effective drainage over a sedimentary bed. We were able to install wired sensor strings at the bed (water pressure, temperature, electrical conductivity and turbidity) and within the glacier (temperature and tilt) in three boreholes. The sensors operated for up to 80+ days before cables stretched and ultimately snapped due to high internal strain. The data collected during this sensor deployment show ice as cold as -21 degrees Celcius; yet, temperature of water in the basal water system was persistently above the local freezing point. With diurnal variations detected in several sensor records, we hypothesise that surface water lubricates the ice flow while also warming basal ice. The fast basal motion of Store Glacier not only occurs by basal sliding, but from high rates of concentrated strain in the bottom third of the glacier. Deployment of an autonomous phase-sensitive radar near the drill site complements the data collected by sensors installed in boreholes, as internal reflectors measured at hourly timescale show very high, and highly variable internal strain within the glacier. In 2016, we plan to install new sensors while also sampling cores from the bed.

Ultrafast vibrational spectroscopy (2D-IR) of CO{sub 2} in ionic liquids: Carbon capture from carbon dioxide’s point of view

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brinzer, Thomas; Berquist, Eric J.; Ren, Zhe

2015-06-07

The CO{sub 2}ν{sub 3} asymmetric stretching mode is established as a vibrational chromophore for ultrafast two-dimensional infrared (2D-IR) spectroscopic studies of local structure and dynamics in ionic liquids, which are of interest for carbon capture applications. CO{sub 2} is dissolved in a series of 1-butyl-3-methylimidazolium-based ionic liquids ([C{sub 4}C{sub 1}im][X], where [X]{sup −} is the anion from the series hexafluorophosphate (PF{sub 6}{sup −}), tetrafluoroborate (BF{sub 4}{sup −}), bis-(trifluoromethyl)sulfonylimide (Tf{sub 2}N{sup −}), triflate (TfO{sup −}), trifluoroacetate (TFA{sup −}), dicyanamide (DCA{sup −}), and thiocyanate (SCN{sup −})). In the ionic liquids studied, the ν{sub 3} center frequency is sensitive to the local solvationmore » environment and reports on the timescales for local structural relaxation. Density functional theory calculations predict charge transfer from the anion to the CO{sub 2} and from CO{sub 2} to the cation. The charge transfer drives geometrical distortion of CO{sub 2}, which in turn changes the ν{sub 3} frequency. The observed structural relaxation timescales vary by up to an order of magnitude between ionic liquids. Shoulders in the 2D-IR spectra arise from anharmonic coupling of the ν{sub 2} and ν{sub 3} normal modes of CO{sub 2}. Thermal fluctuations in the ν{sub 2} population stochastically modulate the ν{sub 3} frequency and generate dynamic cross-peaks. These timescales are attributed to the breakup of ion cages that create a well-defined local environment for CO{sub 2}. The results suggest that the picosecond dynamics of CO{sub 2} are gated by local diffusion of anions and cations.« less

Universality classes of fluctuation dynamics in hierarchical complex systems

NASA Astrophysics Data System (ADS)

Macêdo, A. M. S.; González, Iván R. Roa; Salazar, D. S. P.; Vasconcelos, G. L.

2017-03-01

A unified approach is proposed to describe the statistics of the short-time dynamics of multiscale complex systems. The probability density function of the relevant time series (signal) is represented as a statistical superposition of a large time-scale distribution weighted by the distribution of certain internal variables that characterize the slowly changing background. The dynamics of the background is formulated as a hierarchical stochastic model whose form is derived from simple physical constraints, which in turn restrict the dynamics to only two possible classes. The probability distributions of both the signal and the background have simple representations in terms of Meijer G functions. The two universality classes for the background dynamics manifest themselves in the signal distribution as two types of tails: power law and stretched exponential, respectively. A detailed analysis of empirical data from classical turbulence and financial markets shows excellent agreement with the theory.

Utilization of Short-Simulations for Tuning High-Resolution Climate Model

NASA Astrophysics Data System (ADS)

Lin, W.; Xie, S.; Ma, P. L.; Rasch, P. J.; Qian, Y.; Wan, H.; Ma, H. Y.; Klein, S. A.

2016-12-01

Many physical parameterizations in atmospheric models are sensitive to resolution. Tuning the models that involve a multitude of parameters at high resolution is computationally expensive, particularly when relying primarily on multi-year simulations. This work describes a complementary set of strategies for tuning high-resolution atmospheric models, using ensembles of short simulations to reduce the computational cost and elapsed time. Specifically, we utilize the hindcast approach developed through the DOE Cloud Associated Parameterization Testbed (CAPT) project for high-resolution model tuning, which is guided by a combination of short (< 10 days ) and longer ( 1 year) Perturbed Parameters Ensemble (PPE) simulations at low resolution to identify model feature sensitivity to parameter changes. The CAPT tests have been found to be effective in numerous previous studies in identifying model biases due to parameterized fast physics, and we demonstrate that it is also useful for tuning. After the most egregious errors are addressed through an initial "rough" tuning phase, longer simulations are performed to "hone in" on model features that evolve over longer timescales. We explore these strategies to tune the DOE ACME (Accelerated Climate Modeling for Energy) model. For the ACME model at 0.25° resolution, it is confirmed that, given the same parameters, major biases in global mean statistics and many spatial features are consistent between Atmospheric Model Intercomparison Project (AMIP)-type simulations and CAPT-type hindcasts, with just a small number of short-term simulations for the latter over the corresponding season. The use of CAPT hindcasts to find parameter choice for the reduction of large model biases dramatically improves the turnaround time for the tuning at high resolution. Improvement seen in CAPT hindcasts generally translates to improved AMIP-type simulations. An iterative CAPT-AMIP tuning approach is therefore adopted during each major tuning cycle, with the former to survey the likely responses and narrow the parameter space, and the latter to verify the results in climate context along with assessment in greater detail once an educated set of parameter choice is selected. Limitations on using short-term simulations for tuning climate model are also discussed.

Direct simulation of amphiphilic nanoparticle mediated membrane interactions

NASA Astrophysics Data System (ADS)

Tahir, Mukarram; Alexander-Katz, Alfredo

Membrane fusion is a critical step in the transport of biological cargo through membrane-bound compartments like vesicles. Membrane proteins that alleviate energy barriers for initial stalk formation and eventual rupture of the hemifusion intermediate during fusion generally assist this process. Gold nanoparticles functionalized with a combination of hydrophobic and hydrophilic alkanethiol ligands have recently been shown to induce membrane re-arrangements that are similar to those associated with these fusion proteins. In this work, we utilize molecular dynamics simulation to systematically design nanoparticles that exhibit targeted interactions with membranes. We introduce a method for rapidly parameterizing nanoparticle topology for the MARTINI biomolecular force field to permit long timescale simulation of their interactions with lipid bilayers. We leverage this model to investigate how ligand chemistry governs the nanoparticle's insertion efficacy and the perturbations it generates in the membrane environment. We further demonstrate through unbiased simulations that these nanoparticles can direct the fusion of lipid assemblies such as micelles and vesicles in a manner that mimics the function of biological fusion peptides and SNARE proteins.

Model under-representation of decadal Pacific trade wind trends and its link to tropical Atlantic bias

NASA Astrophysics Data System (ADS)

Kajtar, Jules B.; Santoso, Agus; McGregor, Shayne; England, Matthew H.; Baillie, Zak

2018-02-01

The strengthening of the Pacific trade winds in recent decades has been unmatched in the observational record stretching back to the early twentieth century. This wind strengthening has been connected with numerous climate-related phenomena, including accelerated sea-level rise in the western Pacific, alterations to Indo-Pacific ocean currents, increased ocean heat uptake, and a slow-down in the rate of global-mean surface warming. Here we show that models in the Coupled Model Intercomparison Project phase 5 underestimate the observed range of decadal trends in the Pacific trade winds, despite capturing the range in decadal sea surface temperature (SST) variability. Analysis of observational data suggests that tropical Atlantic SST contributes considerably to the Pacific trade wind trends, whereas the Atlantic feedback in coupled models is muted. Atmosphere-only simulations forced by observed SST are capable of recovering the time-variation and the magnitude of the trade wind trends. Hence, we explore whether it is the biases in the mean or in the anomalous SST patterns that are responsible for the under-representation in fully coupled models. Over interannual time-scales, we find that model biases in the patterns of Atlantic SST anomalies are the strongest source of error in the precipitation and atmospheric circulation response. In contrast, on decadal time-scales, the magnitude of the model biases in Atlantic mean SST are directly linked with the trade wind variability response.

Mechanical Fluidity of Fully Suspended Biological Cells

PubMed Central

Maloney, John M.; Lehnhardt, Eric; Long, Alexandra F.; Van Vliet, Krystyn J.

2013-01-01

Mechanical characteristics of single biological cells are used to identify and possibly leverage interesting differences among cells or cell populations. Fluidity—hysteresivity normalized to the extremes of an elastic solid or a viscous liquid—can be extracted from, and compared among, multiple rheological measurements of cells: creep compliance versus time, complex modulus versus frequency, and phase lag versus frequency. With multiple strategies available for acquisition of this nondimensional property, fluidity may serve as a useful and robust parameter for distinguishing cell populations, and for understanding the physical origins of deformability in soft matter. Here, for three disparate eukaryotic cell types deformed in the suspended state via optical stretching, we examine the dependence of fluidity on chemical and environmental influences at a timescale of ∼1 s. We find that fluidity estimates are consistent in the time and frequency domains under a structural damping (power-law or fractional-derivative) model, but not under an equivalent-complexity, lumped-component (spring-dashpot) model; the latter predicts spurious time constants. Although fluidity is suppressed by chemical cross-linking, we find that ATP depletion in the cell does not measurably alter the parameter, and we thus conclude that active ATP-driven events are not a crucial enabler of fluidity during linear viscoelastic deformation of a suspended cell. Finally, by using the capacity of optical stretching to produce near-instantaneous increases in cell temperature, we establish that fluidity increases with temperature—now measured in a fully suspended, sortable cell without the complicating factor of cell-substratum adhesion. PMID:24138852

Observation of Water-Protein Interaction Dynamics with Broadband Two-Dimensional Infrared Spectroscopy

NASA Astrophysics Data System (ADS)

De Marco, Luigi; Haky, Andrew; Tokmakoff, Andrei

Two-dimensional infrared (2D IR) spectroscopy has proven itself an indispensable tool for studying molecular dynamics and intermolecular interactions on ultrafast timescales. Using a novel source of broadband mid-IR pulses, we have collected 2D IR spectra of protein films at varying levels of hydration. With 2D IR, we can directly observe coupling between water's motions and the protein's. Protein films provide us with the ability to discriminate hydration waters from bulk water and thus give us access to studying water dynamics along the protein backbone, fluctuations in the protein structure, and the interplay between the molecular dynamics of the two. We present two representative protein films: poly-L-proline (PLP) and hen egg-white lysozyme (HEWL). Having no N-H groups, PLP allows us to look at water dynamics without interference from resonant energy transfer between the protein N-H stretch and the water O-H stretch. We conclude that at low hydration levels water-protein interactions dominate, and the water's dynamics are tied to those of the protein. In HEWL films, we take advantage of the robust secondary structure to partially deuterate the film, allowing us to spectrally distinguish the protein core from the exterior. From this, we show that resonant energy transfer to water provides an effective means of dissipating excess energy within the protein, while maintaining the structure. These methods are general and can easily be extended to studying specific protein-water interactions.

Overstable librations can account for the paucity of mean motion resonances among exoplanet pairs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldreich, Peter; Schlichting, Hilke E., E-mail: pmg@ias.edu, E-mail: hilke@mit.edu

2014-02-01

We assess the multi-planet systems discovered by the Kepler satellite in terms of current ideas about orbital migration and eccentricity damping due to planet-disk interactions. Our primary focus is on first order mean motion resonances, which we investigate analytically to lowest order in eccentricity. Only a few percent of planet pairs are in close proximity to a resonance. However, predicted migration rates (parameterized by τ{sub n}=n/| n-dot |) imply that during convergent migration most planets would have been captured into first order resonances. Eccentricity damping (parameterized by τ{sub e}=e/| e-dot |) offers a plausible resolution. Estimates suggest τ {sub e}/τmore » {sub n} ∼ (h/a){sup 2} ∼ 10{sup –2}, where h/a is the ratio of disk thickness to radius. Together, eccentricity damping and orbital migration give rise to an equilibrium eccentricity, e {sub eq} ∼ (τ {sub e}/τ {sub n}){sup 1/2}. Capture is permanent provided e {sub eq} ≲ μ{sup 1/3}, where μ denotes the planet to star mass ratio. But for e {sub eq} ≳ μ{sup 1/3}, capture is only temporary because librations around equilibrium are overstable and lead to passage through resonance on timescale τ {sub e}. Most Kepler planet pairs have e {sub eq} > μ{sup 1/3}. Since τ {sub n} >> τ {sub e} is the timescale for migration between neighboring resonances, only a modest percentage of pairs end up trapped in resonances after the disk disappears. Thus the paucity of resonances among Kepler pairs should not be taken as evidence for in situ planet formation or the disruptive effects of disk turbulence. Planet pairs close to a mean motion resonance typically exhibit period ratios 1%-2% larger than those for exact resonance. The direction of this shift undoubtedly reflects the same asymmetry that requires convergent migration for resonance capture. Permanent resonance capture at these separations from exact resonance would demand μ(τ {sub n}/τ {sub e}){sup 1/2} ≳ 0.01, a value that estimates of μ from transit data and (τ {sub e}/τ {sub n}){sup 1/2} from theory are insufficient to match. Plausible alternatives involve eccentricity damping during or after disk dispersal. The overstability referred to above has applications beyond those considered in this investigation. It was discovered numerically by Meyer and Wisdom in their study of the tidal evolution of Saturn's satellites.« less

On the use of nudging techniques for regional climate modeling: application for tropical convection

NASA Astrophysics Data System (ADS)

Pohl, Benjamin; Crétat, Julien

2014-09-01

Using a large set of WRF ensemble simulations at 70-km horizontal resolution over a domain encompassing the Warm Pool region and its surroundings [45°N-45°S, 10°E-240°E], this study aims at quantifying how nudging techniques can modify the simulation of deep atmospheric convection. Both seasonal mean climate, transient variability at intraseasonal timescales, and the respective weight of internal (stochastic) and forced (reproducible) variability are considered. Sensitivity to a large variety of nudging settings (nudged variables and layers and nudging strength) and to the model physics (using 3 convective parameterizations) is addressed. Integrations are carried out during a 7-month season characterized by neutral background conditions and strong intraseasonal variability. Results show that (1) the model responds differently to the nudging from one parameterization to another. Biases are decreased by ~50 % for Betts-Miller-Janjic convection against 17 % only for Grell-Dévényi, the scheme producing yet the largest biases; (2) relaxing air temperature is the most efficient way to reduce biases, while nudging the wind increases most co-variability with daily observations; (3) the model's internal variability is drastically reduced and mostly depends on the nudging strength and nudged variables; (4) interrupting the relaxation before the end of the simulations leads to an abrupt convergence towards the model's natural solution, with no clear effects on the simulated climate after a few days. The usefulness and limitations of the approach are finally discussed through the example of the Madden-Julian Oscillation, that the model fails at simulating and that can be artificially and still imperfectly reproduced in relaxation experiments.

Coupled energy-balance/ice-sheet model simulations of the glacial cycle: A possible connection between terminations and terrigenous dust

NASA Astrophysics Data System (ADS)

Peltier, W. Richard; Marshall, Shawn

1995-07-01

We apply a coupled energy-balance/ice-sheet climate model in an investigation of northern hemisphere ice-sheet advance and retreat over the last glacial cycle. When driven only by orbital insolation variations, the model predicts ice-sheet advances over the continents of North America and Eurasia that are in good agreement with geological reconstructions in terms of the timescale of advance and the spatial positioning of the main ice masses. The orbital forcing alone, however, is unable to induce the observed rapid ice-sheet retreat, and we conclude that additional climatic feedbacks not explicitly included in the basic model must be acting. In the analyses presented here we have parameterized a number of potentially important effects in order to test their relative influence on the process of glacial termination. These include marine instability, thermohaline circulation effects, carbon dioxide variations, and snow albedo changes caused by dust loading during periods of high atmospheric aerosol concentration. For the purpose of these analyses the temporal changes in the latter two variables were inferred from ice core records. Of these various influences, our analyses suggest that the albedo variations in the ice-sheet ablation zone caused by dust loading may represent an extremely important ablation mechanism. Using our parameterization of "dirty" snow in the ablation zone we find glacial retreat to be strongly accelerated, such that complete collapse of the otherwise stable Laurentide ice sheet ensues. The last glacial maximum configurations of the Laurentide and Fennoscandian complexes are also brought into much closer accord with the ICE-3G reconstruction of Tushingham and Peltier (1991,1992) and the ICE-4G reconstruction of Peltier (1994) when this effect is reasonably introduced.

A Bayesian methodological framework for accommodating interannual variability of nutrient loading with the SPARROW model

NASA Astrophysics Data System (ADS)

Wellen, Christopher; Arhonditsis, George B.; Labencki, Tanya; Boyd, Duncan

2012-10-01

Regression-type, hybrid empirical/process-based models (e.g., SPARROW, PolFlow) have assumed a prominent role in efforts to estimate the sources and transport of nutrient pollution at river basin scales. However, almost no attempts have been made to explicitly accommodate interannual nutrient loading variability in their structure, despite empirical and theoretical evidence indicating that the associated source/sink processes are quite variable at annual timescales. In this study, we present two methodological approaches to accommodate interannual variability with the Spatially Referenced Regressions on Watershed attributes (SPARROW) nonlinear regression model. The first strategy uses the SPARROW model to estimate a static baseline load and climatic variables (e.g., precipitation) to drive the interannual variability. The second approach allows the source/sink processes within the SPARROW model to vary at annual timescales using dynamic parameter estimation techniques akin to those used in dynamic linear models. Model parameterization is founded upon Bayesian inference techniques that explicitly consider calibration data and model uncertainty. Our case study is the Hamilton Harbor watershed, a mixed agricultural and urban residential area located at the western end of Lake Ontario, Canada. Our analysis suggests that dynamic parameter estimation is the more parsimonious of the two strategies tested and can offer insights into the temporal structural changes associated with watershed functioning. Consistent with empirical and theoretical work, model estimated annual in-stream attenuation rates varied inversely with annual discharge. Estimated phosphorus source areas were concentrated near the receiving water body during years of high in-stream attenuation and dispersed along the main stems of the streams during years of low attenuation, suggesting that nutrient source areas are subject to interannual variability.

High Resolution Global Climate Modeling with GEOS-5: Intense Precipitation, Convection and Tropical Cyclones on Seasonal Time-Scales.

NASA Technical Reports Server (NTRS)

Putnam, WilliamM.

2011-01-01

In 2008 the World Modeling Summit for Climate Prediction concluded that "climate modeling will need-and is ready-to move to fundamentally new high-resolution approaches to capitalize on the seamlessness of the weather-climate continuum." Following from this, experimentation with very high-resolution global climate modeling has gained enhanced priority within many modeling groups and agencies. The NASA Goddard Earth Observing System model (GEOS-5) has been enhanced to provide a capability for the execution at the finest horizontal resolutions POS,SIOle with a global climate model today. Using this high-resolution, non-hydrostatic version of GEOS-5, we have developed a unique capability to explore the intersection of weather and climate within a seamless prediction system. Week-long weather experiments, to mUltiyear climate simulations at global resolutions ranging from 3.5- to 14-km have demonstrated the predictability of extreme events including severe storms along frontal systems, extra-tropical storms, and tropical cyclones. The primary benefits of high resolution global models will likely be in the tropics, with better predictions of the genesis stages of tropical cyclones and of the internal structure of their mature stages. Using satellite data we assess the accuracy of GEOS-5 in representing extreme weather phenomena, and their interaction within the global climate on seasonal time-scales. The impacts of convective parameterization and the frequency of coupling between the moist physics and dynamics are explored in terms of precipitation intensity and the representation of deep convection. We will also describe the seasonal variability of global tropical cyclone activity within a global climate model capable of representing the most intense category 5 hurricanes.

Diffusion of volatile organics through porous snow: impact of surface adsorption and grain boundaries

NASA Astrophysics Data System (ADS)

Bartels-Rausch, T.; Wren, S. N.; Schreiber, S.; Riche, F.; Schneebeli, M.; Ammann, M.

2013-07-01

Release of trace gases from surface snow on earth drives atmospheric chemistry, especially in the polar regions. The gas-phase diffusion of methanol and of acetone through the interstitial air of snow was investigated in a well-controlled laboratory study in the temperature range of 223 to 263 K. The aim of this study was to evaluate how the structure of the snowpack, the interaction of the trace gases with the snow surface, and the grain boundaries influence the diffusion on timescales up to 1 h. The diffusive loss of these two volatile organics into packed snow samples was measured using a chemical ionization mass spectrometer. The structure of the snow was analysed by means of X-ray-computed micro-tomography. The observed diffusion profiles could be well described based on gas-phase diffusion and the known structure of the snow sample at temperatures ≥ 253 K. At colder temperatures, surface interactions start to dominate the diffusive transport. Parameterizing these interactions in terms of adsorption to the solid ice surface, i.e. using temperature-dependent air-ice partitioning coefficients, better described the observed diffusion profiles than the use of air-liquid partitioning coefficients. No changes in the diffusive fluxes were observed by increasing the number of grain boundaries in the snow sample by a factor of 7, indicating that for these volatile organic trace gases, uptake into grain boundaries does not play a role on the timescale of diffusion through porous surface snow. For this, a snow sample with an artificially high amount of ice grains was produced and the grain boundary surface measured using thin sections. In conclusion, we have shown that the diffusivity can be predicted when the structure of the snowpack and the partitioning of the trace gas to solid ice is known.

Diffusion of volatile organics through porous snow: impact of surface adsorption and grain boundaries

NASA Astrophysics Data System (ADS)

Bartels-Rausch, T.; Wren, S. N.; Schreiber, S.; Riche, F.; Schneebeli, M.; Ammann, M.

2013-03-01

Release of trace gases from surface snow on Earth drives atmospheric chemistry, especially in the polar regions. The gas-phase diffusion of methanol and of acetone through the interstitial air of snow was investigated in a well-controlled laboratory study in the temperature range of 223 to 263 K. The aim of this study was to evaluate how the structure of the snowpack, the interaction of the trace gases with the snow surface, and the grain boundaries influence the diffusion on timescales up to 1 h. The diffusive loss of these two volatile organics into packed snow samples was measured using a chemical ionization mass spectrometer. The structure of the snow was analyzed by means of X-ray computed micro-tomography. The observed diffusion profiles could be well described based on gas-phase diffusion and the known structure of the snow sample at temperatures ≥ 253 K. At colder temperatures surface interactions start to dominate the diffusive transport. Parameterizing these interactions in terms of adsorption to the solid ice surface, i.e. using temperature dependent air-ice partitioning coefficients, better described the observed diffusion profiles than the use of air-liquid partitioning coefficients. No changes in the diffusive fluxes were observed by increasing the number of grain boundaries in the snow sample by a factor of 7, indicating that for these volatile organic trace gases, uptake into grain boundaries does not play a role on the timescale of diffusion through porous surface snow. In conclusion, we have shown that the diffusivity can be predicted when the structure of the snowpack and the partitioning of the trace gas to solid ice is known.

Pan-European climate at convection-permitting scale: a model intercomparison study

NASA Astrophysics Data System (ADS)

Berthou, Ségolène; Kendon, Elizabeth J.; Chan, Steven C.; Ban, Nikolina; Leutwyler, David; Schär, Christoph; Fosser, Giorgia

2018-03-01

We investigate the effect of using convection-permitting models (CPMs) spanning a pan-European domain on the representation of precipitation distribution at a climatic scale. In particular we compare two 2.2 km models with two 12 km models run by ETH Zürich (ETH-12 km and ETH-2.2 km) and the Met-Office (UKMO-12 km and UKMO-2.2 km). The two CPMs yield qualitatively similar differences to the precipitation climatology compared to the 12 km models, despite using different dynamical cores and different parameterization packages. A quantitative analysis confirms that the CPMs give the largest differences compared to 12 km models in the hourly precipitation distribution in regions and seasons where convection is a key process: in summer across the whole of Europe and in autumn over the Mediterranean Sea and coasts. Mean precipitation is increased over high orography, with an increased amplitude of the diurnal cycle. We highlight that both CPMs show an increased number of moderate to intense short-lasting events and a decreased number of longer-lasting low-intensity events everywhere, correcting (and often over-correcting) biases in the 12 km models. The overall hourly distribution and the intensity of the most intense events is improved in Switzerland and to a lesser extent in the UK but deteriorates in Germany. The timing of the peak in the diurnal cycle of precipitation is improved. At the daily time-scale, differences in the precipitation distribution are less clear but the greater Alpine region stands out with the largest differences. Also, Mediterranean autumnal intense events are better represented at the daily time-scale in both 2.2 km models, due to improved representation of mesoscale processes.

Transient responses of SFG spectra of D 2O ice/CO/Pt(1 1 1) interface with irradiation of ultra-short NIR pump pulses

NASA Astrophysics Data System (ADS)

Kubota, Jun; Wada, Akihide; Domen, Kazunari; Kano, Satoru S.

2002-08-01

The behavior of D 2O ice on CO/Pt(1 1 1) and Pt(1 1 1) under the irradiation of near-IR pulses (NIR) was studied by sum-frequency generation (SFG) spectroscopy. The peaks assigned to the O-D stretching modes of ice were obtained for the first 30 molecular layers on Pt(1 1 1). When the D2O/ CO/ Pt(1 1 1) was irradiated, the signal of D 2O was weakened after 500 ps, but that of CO was weakened immediately after the pumping. A similar time response was observed for the D 2O peak in D2O/ Pt(1 1 1) . The weakening of SFG is attributed to the broadening of bands due to thermal excitation. This indicates that the energy of the pump pulse is deposited on the Pt(1 1 1) surface and diffused into the layers of D 2O ice in the 500 ps timescale.

Explosive Leidenfrost droplets

NASA Astrophysics Data System (ADS)

Colinet, Pierre; Moreau, Florian; Dorbolo, Stéphane

2017-11-01

We show that Leidenfrost droplets made of an aqueous solution of surfactant undergo a violent explosion in a wide range of initial volumes and concentrations. This unexpected behavior turns out to be triggered by the formation of a gel-like shell, followed by a sharp temperature increase. Comparing a simple model of the radial surfactant distribution inside a spherical droplet with experiments allows highlighting the existence of a critical surface concentration for the shell to form. The temperature rise (attributed to boiling point elevation with surface concentration) is a key feature leading to the explosion, instead of the implosion (buckling) scenario reported by other authors. Indeed, under some conditions, this temperature increase is shown to be sufficient to trigger nucleation and growth of vapor bubbles in the highly superheated liquid bulk, stretching the surrounding elastic shell up to its rupture limit. The successive timescales characterizing this explosion sequence are also discussed. Funding sources: F.R.S. - FNRS (ODILE and DITRASOL projects, RD and SRA positions of P. Colinet and S. Dorbolo), BELSPO (IAP 7/38 MicroMAST project).

Evidence of impurity and boundary effects on magnetic monopole dynamics in spin ice

NASA Astrophysics Data System (ADS)

Revell, H. M.; Yaraskavitch, L. R.; Mason, J. D.; Ross, K. A.; Noad, H. M. L.; Dabkowska, H. A.; Gaulin, B. D.; Henelius, P.; Kycia, J. B.

2013-01-01

Electrical resistance is a crucial and well-understood property of systems ranging from computer microchips to nerve impulse propagation in the human body. Here we study the motion of magnetic charges in spin ice and find that extra spins inserted in Dy2Ti2O7 trap magnetic monopole excitations and provide the first example of how defects in a spin-ice material obstruct the flow of monopoles--a magnetic version of residual resistance. We measure the time-dependent magnetic relaxation in Dy2Ti2O7 and show that it decays with a stretched exponential followed by a very slow long-time tail. In a Monte Carlo simulation governed by Metropolis dynamics we show that surface effects and a very low level of stuffed spins (0.30%)--magnetic Dy ions substituted for non-magnetic Ti ions--cause these signatures in the relaxation. In addition, we find evidence that the rapidly diverging experimental timescale is due to a temperature-dependent attempt rate proportional to the monopole density.

Nonequilibrium thermodynamics of dilute polymer solutions in flow.

PubMed

Latinwo, Folarin; Hsiao, Kai-Wen; Schroeder, Charles M

2014-11-07

Modern materials processing applications and technologies often occur far from equilibrium. To this end, the processing of complex materials such as polymer melts and nanocomposites generally occurs under strong deformations and flows, conditions under which equilibrium thermodynamics does not apply. As a result, the ability to determine the nonequilibrium thermodynamic properties of polymeric materials from measurable quantities such as heat and work is a major challenge in the field. Here, we use work relations to show that nonequilibrium thermodynamic quantities such as free energy and entropy can be determined for dilute polymer solutions in flow. In this way, we determine the thermodynamic properties of DNA molecules in strong flows using a combination of simulations, kinetic theory, and single molecule experiments. We show that it is possible to calculate polymer relaxation timescales purely from polymer stretching dynamics in flow. We further observe a thermodynamic equivalence between nonequilibrium and equilibrium steady-states for polymeric systems. In this way, our results provide an improved understanding of the energetics of flowing polymer solutions.

Investigating vibrational relaxation in cyanide-bridged transition metal mixed-valence complexes using two-dimensional infrared and infrared pump-probe spectroscopies

PubMed Central

Slenkamp, Karla M.; Lynch, Michael S.; Brookes, Jennifer F.; Bannan, Caitlin C.; Daifuku, Stephanie L.; Khalil, Munira

2016-01-01

Using polarization-selective two-dimensional infrared (2D IR) and infrared pump-probe spectroscopies, we study vibrational relaxation of the four cyanide stretching (νCN) vibrations found in [(NH3)5RuIIINCFeII(CN)5]− (FeRu) dissolved in D2O or formamide and [(NC)5FeIICNPtIV(NH3)4NCFeII(CN)5]4− (FePtFe) dissolved in D2O. These cyanide-bridged transition metal complexes serve as models for understanding the role high frequency vibrational modes play in metal-to-metal charge transfers over a bridging ligand. However, there is currently little information about vibrational relaxation and dephasing dynamics of the anharmonically coupled νCN modes in the electronic ground state of these complexes. IR pump-probe experiments reveal that the vibrational lifetimes of the νCN modes are ∼2 times faster when FeRu is dissolved in D2O versus formamide. They also reveal that the vibrational lifetimes of the νCN modes of FePtFe in D2O are almost four times as long as for FeRu in D2O. Combined with mode-specific relaxation dynamics measured from the 2D IR experiments, the IR pump-probe experiments also reveal that intramolecular vibrational relaxation is occurring in all three systems on ∼1 ps timescale. Center line slope dynamics, which have been shown to be a measure of the frequency-frequency correlation function, reveal that the radial, axial, and trans νCN modes exhibit a ∼3 ps timescale for frequency fluctuations. This timescale is attributed to the forming and breaking of hydrogen bonds between each mode and the solvent. The results presented here along with our previous work on FeRu and FePtFe reveal a picture of coupled anharmonic νCN modes where the spectral diffusion and vibrational relaxation dynamics depend on the spatial localization of the mode on the molecular complex and its specific interaction with the solvent. PMID:27158634

Investigating vibrational relaxation in cyanide-bridged transition metal mixed-valence complexes using two-dimensional infrared and infrared pump-probe spectroscopies.

PubMed

Slenkamp, Karla M; Lynch, Michael S; Brookes, Jennifer F; Bannan, Caitlin C; Daifuku, Stephanie L; Khalil, Munira

2016-03-01

Using polarization-selective two-dimensional infrared (2D IR) and infrared pump-probe spectroscopies, we study vibrational relaxation of the four cyanide stretching (νCN) vibrations found in [(NH3)5Ru(III)NCFe(II)(CN)5](-) (FeRu) dissolved in D2O or formamide and [(NC)5Fe(II)CNPt(IV)(NH3)4NCFe(II)(CN)5](4-) (FePtFe) dissolved in D2O. These cyanide-bridged transition metal complexes serve as models for understanding the role high frequency vibrational modes play in metal-to-metal charge transfers over a bridging ligand. However, there is currently little information about vibrational relaxation and dephasing dynamics of the anharmonically coupled νCN modes in the electronic ground state of these complexes. IR pump-probe experiments reveal that the vibrational lifetimes of the νCN modes are ∼2 times faster when FeRu is dissolved in D2O versus formamide. They also reveal that the vibrational lifetimes of the νCN modes of FePtFe in D2O are almost four times as long as for FeRu in D2O. Combined with mode-specific relaxation dynamics measured from the 2D IR experiments, the IR pump-probe experiments also reveal that intramolecular vibrational relaxation is occurring in all three systems on ∼1 ps timescale. Center line slope dynamics, which have been shown to be a measure of the frequency-frequency correlation function, reveal that the radial, axial, and trans νCN modes exhibit a ∼3 ps timescale for frequency fluctuations. This timescale is attributed to the forming and breaking of hydrogen bonds between each mode and the solvent. The results presented here along with our previous work on FeRu and FePtFe reveal a picture of coupled anharmonic νCN modes where the spectral diffusion and vibrational relaxation dynamics depend on the spatial localization of the mode on the molecular complex and its specific interaction with the solvent.

Vertical Transport Processes for Inert and Scavenged Species: TRACE-A Measurements

NASA Technical Reports Server (NTRS)

Chatfield, Robert B.; Chan, K. Roland (Technical Monitor)

1997-01-01

The TRACE-A mission of the NASA DC-8 aircraft made a large-scale survey of the tropical and subtropical atmosphere in September and October of 1992. Both In-situ measurements of CO (G. Sachsen NASA Langley) and aerosol size (J. Browell group, NASA Langley) provide excellent data sets with which to constrain vertical transport by planetary boundary layer mixing and deep-cloud cumulus convection. Lidar profiles of aerosol-induced scattering and ozone (also by Bremen) are somewhat require more subtle interpretation as tracers, but the vertical information on layering largely compensates for these complexities. The reason this DC-8 dataset is so useful is that very large areas of biomass burning over Africa and South America provide surface sources of appropriate sizes with which to characterize vertical and horizontal motions; the major limitation of our source description is that biomass burning patterns move considerably every few days, and daily burning inventories are a matter of concurrent, intensive research. We use the Penn State / NCAR MM5 model in an assimilation mode on the synoptic and intercontinental scale, and assess the success it shows in vertical transport descriptions. We find that the general level of emissions suggested by the climatological approach (Will. Has, U. of Montana) appears to be approximately correct, possibly a bit low, for this October, 1992, time period. Vertical transport in planetary boundary layer mixing to 5.5 kin was observed and reproduced in our simulations. Furthermore we find evidence that Blackader "transilient" or matrix-transport scheme is needed, but may require some adaptation in our tracer model: CO seems to exhibit very high values at the top of the planetary boundary layer, a process that stretches the eddy-diffusion parameterization. We will report on progress in improving the deep convective transport of carbon monoxide: the Grail scheme as we used it at 100 kin resolution did not transport enough material to the upper troposphere. We expect to be able to attribute this to either parameterization reasons (inadequacy of this parameterization at the large 100km scale) or other reasons. Nevertheless, the qualitative nature of deep transport by clouds shows up well in the simulations. As for scavengable species, the simulations predict tens of micrograms per standard cubic meter of smoke aerosol in the boundary layer. In a straightforward illustration of our simple bulk-mass scavenging parameterization, to one or two micrograms per standard cubic meter of smoke aerosol in the free troposphere just above the source regions: very high concentrations for the free troposphere. We expect to report on comparisons of these predictions to a variety of observations.

SPM response to tide and river flow in the hyper-turbid Ems River

NASA Astrophysics Data System (ADS)

Winterwerp, Johan C.; Vroom, Julia; Wang, Zheng-B.; Krebs, Martin; Hendriks, Erik C. M.; van Maren, Dirk S.; Schrottke, Kerstin; Borgsmüller, Christine; Schöl, Andreas

2017-05-01

In this paper, we analyse the behaviour of fine sediments in the hyper-turbid Lower Ems River, with focus on the river's upper reaches, a stretch of about 25 km up-estuary of Terborg. Our analysis is based on long records of suspended particulate matter (SPM) from optical backscatter (OBS) measurements close to the bed at seven stations along the river, records of salinity and water level measurements at these stations, acoustic measurements on the vertical mud structure just up-estuary of Terborg and oxygen profiles in the lower 3 m of the water column close to Leerort and Terborg. Further, we use cross-sectionally averaged velocities computed with a calibrated numerical model. Distinction is made between four timescales, i.e. the semi-diurnal tidal timescale, the spring-neap tidal timescale, a timescale around an isolated peak in river flow (i.e. about 3 weeks) and a seasonal timescale. The data suggest that a pool of fluid/soft mud is present in these upper reaches, from up-estuary of Papenburg to a bit down-estuary of Terborg. Between Terborg and Gandersum, SPM values drop rapidly but remain high at a few gram per litre. The pool of fluid/soft mud is entrained/mobilized at the onset of flood, yielding SPM values of many tens gram per litre. This suspension is transported up-estuary with the flood. Around high water slack, part of the suspension settles, being remixed during ebb, while migrating down-estuary, but likely not much further than Terborg. Around low water slack, a large fraction of the sediment settles, reforming the pool of fluid mud. The rapid entrainment from the fluid mud layer after low water slack is only possible when the peak flood velocity exceeds a critical value of around 1 m/s, i.e. when the stratified water column seems to become internally supercritical. If the peak flood velocity does not reach this critical value, f.i. during neap tide, fluid mud is not entrained up to the OBS sensors. Thus, it is not classical tidal asymmetry, but the peak flood velocity itself which governs the hyper-turbid state in the Lower Ems River. The crucial role of river flow and river floods is in reducing these peak flood velocities. During elongated periods of high river flow, in e.g. wintertime, SPM concentrations reduce, and the soft mud deposits consolidate and possibly become locally armoured as well by sand washed in from the river. We have no observations that sediments are washed out of the hyper-turbid zone. Down-estuary of Terborg, where SPM values do not reach hyper-turbid conditions, the SPM dynamics are governed by classical tidal asymmetry and estuarine circulation. Hence, nowhere in the river, sediments are flushed from the upper reaches of the river into the Ems-Dollard estuary during high river flow events. However, exchange of sediment between river and estuary should occur because of tide-induced dispersion.

Chemically reacting fluid flow in exoplanet and brown dwarf atmospheres

NASA Astrophysics Data System (ADS)

Bordwell, Baylee; Brown, Benjamin P.; Oishi, Jeffrey S.

2016-11-01

In the past few decades, spectral observations of planets and brown dwarfs have demonstrated significant deviations from predictions in certain chemical abundances. Starting with Jupiter, these deviations were successfully explained to be the effect of fast dynamics on comparatively slow chemical reactions. These dynamical effects are treated using mixing length theory in what is known as the "quench" approximation. In these objects, however, both radiative and convective zones are present, and it is not clear that this approximation applies. To resolve this issue, we solve the fully compressible equations of fluid dynamics in a matched polytropic atmosphere using the state-of-the-art pseudospectral simulation framework Dedalus. Through the inclusion of passive tracers, we explore the transport properties of convective and radiative zones, and verify the classical eddy diffusion parameterization. With the addition of active tracers, we examine the interactions between dynamical and chemical processes using abstract chemical reactions. By locating the quench point (the point at which the dynamical and chemical timescales are the same) in different dynamical regimes, we test the quench approximation, and generate prescriptions for the exoplanet and brown dwarf communities.

Confounding factors in determining causal soil moisture-precipitation feedback

NASA Astrophysics Data System (ADS)

Tuttle, Samuel E.; Salvucci, Guido D.

2017-07-01

Identification of causal links in the land-atmosphere system is important for construction and testing of land surface and general circulation models. However, the land and atmosphere are highly coupled and linked by a vast number of complex, interdependent processes. Statistical methods, such as Granger causality, can help to identify feedbacks from observational data, independent of the different parameterizations of physical processes and spatiotemporal resolution effects that influence feedbacks in models. However, statistical causal identification methods can easily be misapplied, leading to erroneous conclusions about feedback strength and sign. Here, we discuss three factors that must be accounted for in determination of causal soil moisture-precipitation feedback in observations and model output: seasonal and interannual variability, precipitation persistence, and endogeneity. The effect of neglecting these factors is demonstrated in simulated and observational data. The results show that long-timescale variability and precipitation persistence can have a substantial effect on detected soil moisture-precipitation feedback strength, while endogeneity has a smaller effect that is often masked by measurement error and thus is more likely to be an issue when analyzing model data or highly accurate observational data.

Black hole based quantum computing in labs and in the sky

NASA Astrophysics Data System (ADS)

Dvali, Gia; Panchenko, Mischa

2016-08-01

Analyzing some well established facts, we give a model-independent parameterization of black hole quantum computing in terms of a set of macro and micro quantities and their relations. These include the relations between the extraordinarily-small energy gap of black hole qubits and important time-scales of information-processing, such as, scrambling time and Page's time. We then show, confirming and extending previous results, that other systems of nature with identical quantum informatics features are attractive Bose-Einstein systems at the critical point of quantum phase transition. Here we establish a complete isomorphy between the quantum computational properties of these two systems. In particular, we show that the quantum hair of a critical condensate is strikingly similar to the quantum hair of a black hole. Irrespectively whether one takes the similarity between the two systems as a remarkable coincidence or as a sign of a deeper underlying connection, the following is evident. Black holes are not unique in their way of quantum information processing and we can manufacture black hole based quantum computers in labs by taking advantage of quantum criticality.

Reconstruction of late Holocene climate based on tree growth and mechanistic hierarchical models

USGS Publications Warehouse

Tipton, John; Hooten, Mevin B.; Pederson, Neil; Tingley, Martin; Bishop, Daniel

2016-01-01

Reconstruction of pre-instrumental, late Holocene climate is important for understanding how climate has changed in the past and how climate might change in the future. Statistical prediction of paleoclimate from tree ring widths is challenging because tree ring widths are a one-dimensional summary of annual growth that represents a multi-dimensional set of climatic and biotic influences. We develop a Bayesian hierarchical framework using a nonlinear, biologically motivated tree ring growth model to jointly reconstruct temperature and precipitation in the Hudson Valley, New York. Using a common growth function to describe the response of a tree to climate, we allow for species-specific parameterizations of the growth response. To enable predictive backcasts, we model the climate variables with a vector autoregressive process on an annual timescale coupled with a multivariate conditional autoregressive process that accounts for temporal correlation and cross-correlation between temperature and precipitation on a monthly scale. Our multi-scale temporal model allows for flexibility in the climate response through time at different temporal scales and predicts reasonable climate scenarios given tree ring width data.

Unravelling the mechanisms of vibrational relaxation in solution† †All experimental data are archived in the University of Bristol's Research Data Storage Facility (DOI: 10.5523/bris.2vk036f35m5aq2dnlb79c0wcsh). ‡ ‡Electronic supplementary information (ESI) available: Further discussion of spectral lineshapes, concentration dependence of transient absorption data, theoretical calculations, IR-pump IR-probe spectra, transient absorption spectra including animation of spectra. See DOI: 10.1039/c6sc05234g Click here for additional data file. Click here for additional data file.

PubMed Central

Grubb, Michael P.; Coulter, Philip M.; Marroux, Hugo J. B.

2017-01-01

We present a systematic study of the mode-specific vibrational relaxation of NO2 in six weakly-interacting solvents (perfluorohexane, perfluoromethylcyclohexane, perfluorodecalin, carbon tetrachloride, chloroform, and d-chloroform), chosen to elucidate the dominant energy transfer mechanisms in the solution phase. Broadband transient vibrational absorption spectroscopy has allowed us to extract quantum state-resolved relaxation dynamics of the two distinct NO2 fragments produced from the 340 nm photolysis of N2O4 → NO2(X) + NO2(A) and their separate paths to thermal equilibrium. Distinct relaxation pathways are observed for the NO2 bending and stretching modes, even at energies as high as 7000 cm–1 above the potential minimum. Vibrational energy transfer is governed by different interaction mechanisms in the various solvent environments, and proceeds with timescales ranging from 20–1100 ps. NO2 relaxation rates in the perfluorocarbon solvents are identical despite differences in acceptor mode state densities, infrared absorption cross sections, and local solvent structure. Vibrational energy is shown to be transferred to non-vibrational solvent degrees of freedom (V-T) through impulsive collisions with the perfluorocarbon molecules. Conversely, NO2 relaxation in chlorinated solvents is reliant on vibrational resonances (V-V) while V-T energy transfer is inefficient and thermal excitation of the surrounding solvent molecules inhibits faster vibrational relaxation through direct complexation. Intramolecular vibrational redistribution allows the symmetric stretch of NO2 to act as a gateway for antisymmetric stretch energy to exit the molecule. This study establishes an unprecedented level of detail for the cooling dynamics of a solvated small molecule, and provides a benchmark system for future theoretical studies of vibrational relaxation processes in solution. PMID:28451375

Type Ia supernova Hubble residuals and host-galaxy properties

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, A. G.; Aldering, G.; Aragon, C.

2014-03-20

Kim et al. introduced a new methodology for determining peak-brightness absolute magnitudes of type Ia supernovae from multi-band light curves. We examine the relation between their parameterization of light curves and Hubble residuals, based on photometry synthesized from the Nearby Supernova Factory spectrophotometric time series, with global host-galaxy properties. The K13 Hubble residual step with host mass is 0.013 ± 0.031 mag for a supernova subsample with data coverage corresponding to the K13 training; at <<1σ, the step is not significant and lower than previous measurements. Relaxing the data coverage requirement of the Hubble residual step with the host massmore » is 0.045 ± 0.026 mag for the larger sample; a calculation using the modes of the distributions, less sensitive to outliers, yields a step of 0.019 mag. The analysis of this article uses K13 inferred luminosities, as distinguished from previous works that use magnitude corrections as a function of SALT2 color and stretch parameters: steps at >2σ significance are found in SALT2 Hubble residuals in samples split by the values of their K13 x(1) and x(2) light-curve parameters. x(1) affects the light-curve width and color around peak (similar to the Δm {sub 15} and stretch parameters), and x(2) affects colors, the near-UV light-curve width, and the light-curve decline 20-30 days after peak brightness. The novel light-curve analysis, increased parameter set, and magnitude corrections of K13 may be capturing features of SN Ia diversity arising from progenitor stellar evolution.« less

High Resolution Simulations of Future Climate in West Africa Using a Variable-Resolution Atmospheric Model

NASA Astrophysics Data System (ADS)

Adegoke, J. O.; Engelbrecht, F.; Vezhapparambu, S.

2013-12-01

In previous work demonstrated the application of a var¬iable-resolution global atmospheric model, the conformal-cubic atmospheric model (CCAM), across a wide range of spatial and time scales to investigate the ability of the model to provide realistic simulations of present-day climate and plausible projections of future climate change over sub-Saharan Africa. By applying the model in stretched-grid mode the versatility of the model dynamics, numerical formulation and physical parameterizations to function across a range of length scales over the region of interest, was also explored. We primarily used CCAM to illustrate the capability of the model to function as a flexible downscaling tool at the climate-change time scale. Here we report on additional long term climate projection studies performed by downscaling at much higher resolutions (8 Km) over an area that stretches from just south of Sahara desert to the southern coast of the Niger Delta and into the Gulf of Guinea. To perform these simulations, CCAM was provided with synoptic-scale forcing of atmospheric circulation from 2.5 deg resolution NCEP reanalysis at 6-hourly interval and SSTs from NCEP reanalysis data uses as lower boundary forcing. CCAM 60 Km resolution downscaled to 8 Km (Schmidt factor 24.75) then 8 Km resolution simulation downscaled to 1 Km (Schmidt factor 200) over an area approximately 50 Km x 50 Km in the southern Lake Chad Basin (LCB). Our intent in conducting these high resolution model runs was to obtain a deeper understanding of linkages between the projected future climate and the hydrological processes that control the surface water regime in this part of sub-Saharan Africa.

Pion, Kaon, Proton and Antiproton Production in Proton-Proton Collisions

NASA Technical Reports Server (NTRS)

Norbury, John W.; Blattnig, Steve R.

2008-01-01

Inclusive pion, kaon, proton, and antiproton production from proton-proton collisions is studied at a variety of proton energies. Various available parameterizations of Lorentz-invariant differential cross sections as a function of transverse momentum and rapidity are compared with experimental data. The Badhwar and Alper parameterizations are moderately satisfactory for charged pion production. The Badhwar parameterization provides the best fit for charged kaon production. For proton production, the Alper parameterization is best, and for antiproton production the Carey parameterization works best. However, no parameterization is able to fully account for all the data.

Stress relaxation in quasi-two-dimensional self-assembled nanoparticle monolayers

NASA Astrophysics Data System (ADS)

Boucheron, Leandra S.; Stanley, Jacob T.; Dai, Yeling; You, Siheng Sean; Parzyck, Christopher T.; Narayanan, Suresh; Sandy, Alec R.; Jiang, Zhang; Meron, Mati; Lin, Binhua; Shpyrko, Oleg G.

2018-05-01

We experimentally probed the stress relaxation of a monolayer of iron oxide nanoparticles at the water-air interface. Upon drop-casting onto a water surface, the nanoparticles self-assembled into islands of two-dimensional hexagonally close packed crystalline domains surrounded by large voids. When compressed laterally, the voids gradually disappeared as the surface pressure increased. After the compression was stopped, the surface pressure (as measured by a Wilhelmy plate) evolved as a function of the film aging time with three distinct timescales. These aging dynamics were intrinsic to the stressed state built up during the non-equilibrium compression of the film. Utilizing x-ray photon correlation spectroscopy, we measured the characteristic relaxation time (τ ) of in-plane nanoparticle motion as a function of the aging time through both second-order and two-time autocorrelation analysis. Compressed and stretched exponential fitting of the intermediate scattering function yielded exponents (β ) indicating different relaxation mechanisms of the films under different compression stresses. For a monolayer compressed to a lower surface pressure (between 20 mN/m and 30 mN/m), the relaxation time (τ ) decreased continuously as a function of the aging time, as did the fitted exponent, which transitioned from being compressed (>1 ) to stretched (<1 ), indicating that the monolayer underwent a stress release through crystalline domain reorganization. However, for a monolayer compressed to a higher surface pressure (around 40 mN/m), the relaxation time increased continuously and the compressed exponent varied very little from a value of 1.6, suggesting that the system may have been highly stressed and jammed. Despite the interesting stress relaxation signatures seen in these samples, the structural ordering of the monolayer remained the same over the sample lifetime, as revealed by grazing incidence x-ray diffraction.

Hydraulic Conductivity Estimation using Bayesian Model Averaging and Generalized Parameterization

NASA Astrophysics Data System (ADS)

Tsai, F. T.; Li, X.

2006-12-01

Non-uniqueness in parameterization scheme is an inherent problem in groundwater inverse modeling due to limited data. To cope with the non-uniqueness problem of parameterization, we introduce a Bayesian Model Averaging (BMA) method to integrate a set of selected parameterization methods. The estimation uncertainty in BMA includes the uncertainty in individual parameterization methods as the within-parameterization variance and the uncertainty from using different parameterization methods as the between-parameterization variance. Moreover, the generalized parameterization (GP) method is considered in the geostatistical framework in this study. The GP method aims at increasing the flexibility of parameterization through the combination of a zonation structure and an interpolation method. The use of BMP with GP avoids over-confidence in a single parameterization method. A normalized least-squares estimation (NLSE) is adopted to calculate the posterior probability for each GP. We employee the adjoint state method for the sensitivity analysis on the weighting coefficients in the GP method. The adjoint state method is also applied to the NLSE problem. The proposed methodology is implemented to the Alamitos Barrier Project (ABP) in California, where the spatially distributed hydraulic conductivity is estimated. The optimal weighting coefficients embedded in GP are identified through the maximum likelihood estimation (MLE) where the misfits between the observed and calculated groundwater heads are minimized. The conditional mean and conditional variance of the estimated hydraulic conductivity distribution using BMA are obtained to assess the estimation uncertainty.

Dynamic stretching and golf swing performance.

PubMed

Moran, K A; McGrath, T; Marshall, B M; Wallace, E S

2009-02-01

The aim of the present study was to examine the effect of dynamic stretching, static stretching and no stretching, as part of a general warm-up, on golf swing performance with a five-iron. Measures of performance were taken 0 min, 5 min, 15 min and 30 min after stretching. Dynamic stretching produced significantly greater club head speeds than both static stretching (Delta=1.9m.s (-1); p=0.000) and no stretching (Delta=1.7 m.s (-1); p=0.000), and greater ball speeds than both static stretching (Delta=3.5m.s (-1); p=0.003) and no stretching (Delta=3.3m.s (-1); p=0.001). Dynamic stretching produced significantly straighter swing-paths than both static stretching (Delta=-0.61 degrees , p=0.000) and no stretching (Delta=-0.72 degrees , p=0.01). Dynamic stretching also produced more central impact points than the static stretch (Delta=0.7 cm, p=0.001). For the club face angle, there was no effect of either stretch or time. For all of the variables measured, there was no significant difference between the static stretch and no stretch conditions. All of the results were unaffected by the time of measurement after stretching. The results indicate that dynamic stretching should be used as part of a general warm-up in golf.

Assessing the performance of wave breaking parameterizations in shallow waters in spectral wave models

NASA Astrophysics Data System (ADS)

Lin, Shangfei; Sheng, Jinyu

2017-12-01

Depth-induced wave breaking is the primary dissipation mechanism for ocean surface waves in shallow waters. Different parametrizations were developed for parameterizing depth-induced wave breaking process in ocean surface wave models. The performance of six commonly-used parameterizations in simulating significant wave heights (SWHs) is assessed in this study. The main differences between these six parameterizations are representations of the breaker index and the fraction of breaking waves. Laboratory and field observations consisting of 882 cases from 14 sources of published observational data are used in the assessment. We demonstrate that the six parameterizations have reasonable performance in parameterizing depth-induced wave breaking in shallow waters, but with their own limitations and drawbacks. The widely-used parameterization suggested by Battjes and Janssen (1978, BJ78) has a drawback of underpredicting the SWHs in the locally-generated wave conditions and overpredicting in the remotely-generated wave conditions over flat bottoms. The drawback of BJ78 was addressed by a parameterization suggested by Salmon et al. (2015, SA15). But SA15 had relatively larger errors in SWHs over sloping bottoms than BJ78. We follow SA15 and propose a new parameterization with a dependence of the breaker index on the normalized water depth in deep waters similar to SA15. In shallow waters, the breaker index of the new parameterization has a nonlinear dependence on the local bottom slope rather than the linear dependence used in SA15. Overall, this new parameterization has the best performance with an average scatter index of ∼8.2% in comparison with the three best performing existing parameterizations with the average scatter index between 9.2% and 13.6%.

The response of the SSM/I to the marine environment. Part 2: A parameterization of the effect of the sea surface slope distribution on emission and reflection

NASA Technical Reports Server (NTRS)

Petty, Grant W.; Katsaros, Kristina B.

1994-01-01

Based on a geometric optics model and the assumption of an isotropic Gaussian surface slope distribution, the component of ocean surface microwave emissivity variation due to large-scale surface roughness is parameterized for the frequencies and approximate viewing angle of the Special Sensor Microwave/Imager. Independent geophysical variables in the parameterization are the effective (microwave frequency dependent) slope variance and the sea surface temperature. Using the same physical model, the change in the effective zenith angle of reflected sky radiation arising from large-scale roughness is also parameterized. Independent geophysical variables in this parameterization are the effective slope variance and the atmospheric optical depth at the frequency in question. Both of the above model-based parameterizations are intended for use in conjunction with empirical parameterizations relating effective slope variance and foam coverage to near-surface wind speed. These empirical parameterizations are the subject of a separate paper.

Stellar Death by Black Hole: How Tidal Disruption Events Unveil the High Energy Universe

NASA Astrophysics Data System (ADS)

Coughlin, Eric Robert

2017-08-01

When a star comes very close to a supermassive black hole, the tidal field of the hole can be strong enough to deform and stretch the star into a stream of debris. Half of this stellar debris stream returns to the black hole and forms an accretion disk, briefly lighting up the black hole and, in the most extreme cases, launching relativistic jets. These ``tidal disruption events,'' from the initial stellar destruction to the eventual jet production, are the focus of my thesis, and during this talk I will describe some of the theoretical advances we have made in understanding them. I will also discuss more recent work that shows how this relatively simple picture can be more complicated when the disrupting black hole is part of a binary system. Despite the added complexity, I will argue that there is a timescale over which one expects to see variation in the luminosity of a tidal disruption event from a binary supermassive black hole system. Using these predictions and a set of simulations, I will motivate such an interpretation for the superluminous supernova ASASSN-15lh.

Single-molecule analysis of DNA uncoiling by a type II topoisomerase

NASA Astrophysics Data System (ADS)

Strick, Terence R.; Croquette, Vincent; Bensimon, David

2000-04-01

Type II DNA topoisomerases are ubiquitous ATP-dependent enzymes capable of transporting a DNA through a transient double-strand break in a second DNA segment. This enables them to untangle DNA and relax the interwound supercoils (plectonemes) that arise in twisted DNA. In vivo, they are responsible for untangling replicated chromosomes and their absence at mitosis or meiosis ultimately causes cell death. Here we describe a micromanipulation experiment in which we follow in real time a single Drosophila melanogaster topoisomerase II acting on a linear DNA molecule which is mechanically stretched and supercoiled. By monitoring the DNA's extension in the presence of ATP, we directly observe the relaxation of two supercoils during a single catalytic turnover. By controlling the force pulling on the molecule, we determine the variation of the reaction rate with the applied stress. Finally, in the absence of ATP, we observe the clamping of a DNA crossover by a single topoisomerase on at least two different timescales (configurations). These results show that single molecule experiments are a powerful new tool for the study of topoisomerases.

A new methodology for the assessment of hand protection from ultraviolet exposure.

PubMed

Khazova, M; O'Hagan, J B; Grainger, K J-L

2006-01-01

A number of industrial applications and public services involve occupational exposure to ultraviolet radiation (UVR) from a variety of lamps and lasers. The aim of this study was to develop a methodology for the assessment of the UV protection level for disposable gloves. Glove UV protection factor is defined as a time-scale increase in exposure permitted for the hand protected by a glove with respect to an unprotected hand. Our study showed that for all tested gloves a change in UVR attenuation with stretching is characteristic for the type of glove material and can be included as a scaling factor in the definition of UVR protection. Glove material has a bigger effect on UVR protection level than variations in the glove thickness or its colour. Examples of assessment of the 'worst case scenario' are compared with the protection level against a number of sources, together with the guidance on a simplified evaluation protocol. An application-specific assessment, illustrated for 'SmartWater' forensic examinations and biological trans-illuminators, demonstrates that some gloves provide inadequate protection against occupational UV exposure.

An eleven-year validation of a physically-based distributed dynamic ecohydorological model tRIBS+VEGGIE: Walnut Gulch Experimental Watershed

NASA Astrophysics Data System (ADS)

Sivandran, G.; Bisht, G.; Ivanov, V. Y.; Bras, R. L.

2008-12-01

A coupled, dynamic vegetation and hydrologic model, tRIBS+VEGGIE, was applied to the semiarid Walnut Gulch Experimental Watershed in Arizona. The physically-based, distributed nature of the coupled model allows for parameterization and simulation of watershed vegetation-water-energy dynamics on timescales varying from hourly to interannual. The model also allows for explicit spatial representation of processes that vary due to complex topography, such as lateral redistribution of moisture and partitioning of radiation with respect to aspect and slope. Model parameterization and forcing was conducted using readily available databases for topography, soil types, and land use cover as well as the data from network of meteorological stations located within the Walnut Gulch watershed. In order to test the performance of the model, three sets of simulations were conducted over an 11 year period from 1997 to 2007. Two simulations focus on heavily instrumented nested watersheds within the Walnut Gulch basin; (i) Kendall watershed, which is dominated by annual grasses; and (ii) Lucky Hills watershed, which is dominated by a mixture of deciduous and evergreen shrubs. The third set of simulations cover the entire Walnut Gulch Watershed. Model validation and performance were evaluated in relation to three broad categories; (i) energy balance components: the network of meteorological stations were used to validate the key energy fluxes; (ii) water balance components: the network of flumes, rain gauges and soil moisture stations installed within the watershed were utilized to validate the manner in which the model partitions moisture; and (iii) vegetation dynamics: remote sensing products from MODIS were used to validate spatial and temporal vegetation dynamics. Model results demonstrate satisfactory spatial and temporal agreement with observed data, giving confidence that key ecohydrological processes can be adequately represented for future applications of tRIBS+VEGGIE in regional modeling of land-atmosphere interactions.

On the competition among aerosol number, size and composition in predicting CCN variability: a multi-annual field study in an urbanized desert.

PubMed

Crosbie, E; Youn, J-S; Balch, B; Wonaschütz, A; Shingler, T; Wang, Z; Conant, W C; Betterton, E A; Sorooshian, A

2015-02-10

A 2-year data set of measured CCN (cloud condensation nuclei) concentrations at 0.2 % supersaturation is combined with aerosol size distribution and aerosol composition data to probe the effects of aerosol number concentrations, size distribution and composition on CCN patterns. Data were collected over a period of 2 years (2012-2014) in central Tucson, Arizona: a significant urban area surrounded by a sparsely populated desert. Average CCN concentrations are typically lowest in spring (233 cm -3 ), highest in winter (430 cm -3 ) and have a secondary peak during the North American monsoon season (July to September; 372 cm -3 ). There is significant variability outside of seasonal patterns, with extreme concentrations (1 and 99 % levels) ranging from 56 to 1945 cm -3 as measured during the winter, the season with highest variability. Modeled CCN concentrations based on fixed chemical composition achieve better closure in winter, with size and number alone able to predict 82% of the variance in CCN concentration. Changes in aerosol chemical composition are typically aligned with changes in size and aerosol number, such that hygroscopicity can be parameterized even though it is still variable. In summer, models based on fixed chemical composition explain at best only 41% (pre-monsoon) and 36% (monsoon) of the variance. This is attributed to the effects of secondary organic aerosol (SOA) production, the competition between new particle formation and condensational growth, the complex interaction of meteorology, regional and local emissions and multi-phase chemistry during the North American monsoon. Chemical composition is found to be an important factor for improving predictability in spring and on longer timescales in winter. Parameterized models typically exhibit improved predictive skill when there are strong relationships between CCN concentrations and the prevailing meteorology and dominant aerosol physicochemical processes, suggesting that similar findings could be possible in other locations with comparable climates and geography.

Conditions and timescales for welding block-and-ash flow deposits

NASA Astrophysics Data System (ADS)

Heap, M. J.; Kolzenburg, S.; Russell, J. K.; Campbell, M. E.; Welles, J.; Farquharson, J. I.; Ryan, A.

2014-12-01

Welding of pyroclastic deposits to reform a coherent rock mass is a common phenomenon, especially for pumiceous pyroclastic density current deposits (i.e., ignimbrites). However, and despite the pervasive abundance of block-and-ash flow (BAF) deposits in the geological and modern record, instances of strongly welded BAF deposits are few. Here, we present a series of high-temperature (800-900 °C) compaction experiments designed to map the conditions (deposit thickness/stress and temperature/viscosity) and timescales that permit or inhibit the welding of BAF deposits. Our experiments were performed on unconsolidated aggregates (containing an ash and lapilli component) derived from crushed and sieved lava blocks (containing 25% crystals) taken from the well-documented welded BAF deposit at Mount Meager volcano (British Columbia, Canada). The experiments demonstrate that welding efficiency increases with increasing time and temperature. Progressive welding is expressed by increasing axial strain, porosity loss, and bulk density. The rate of change of each of these physical properties reduces as welding progresses. Microstructural analysis of the experimental products shows that the loss of interclast porosity during welding results from the progressive sintering and amalgamation of vitric fragments, and that the pore shape changes from sub-equant pores to stretched lenses sandwiched between vitric and crystal fragments. The coincidence between the microstructure and rock physical properties of the natural and experimental samples highlight that we have successfully reproduced welded BAF in the laboratory. Furthermore, our permeability measurements highlight a hysteresis in the return journey of the "there-and-back-again" volcanic permeability cycle (expressed by an increase in permeability due to vesiculation and fragmentation followed by a decrease due to welding). This hysteresis cannot be described by a single porosity-permeability power law relationship and reflects the change in pore shape and connectivity during welding. Finally, we show that a simple model for welding can accurately forecast the welding timescales of the BAF deposit at Mount Meager (as reconstructed from the collapse of the Lillooet River valley dam) using our experimental data. We use this validation as a platform to provide a universal window for the welding of BAF deposits, also applicable for comparable welded deposits (e.g., welded autobreccias in block-lavas and lava domes), for a broad range of deposit thickness (or stress) and effective viscosity.

Leveraging organismal biology to forecast the effects of climate change.

PubMed

Buckley, Lauren B; Cannistra, Anthony F; John, Aji

2018-04-26

Despite the pressing need for accurate forecasts of ecological and evolutionary responses to environmental change, commonly used modelling approaches exhibit mixed performance because they omit many important aspects of how organisms respond to spatially and temporally variable environments. Integrating models based on organismal phenotypes at the physiological, performance and fitness levels can improve model performance. We summarize current limitations of environmental data and models and discuss potential remedies. The paper reviews emerging techniques for sensing environments at fine spatial and temporal scales, accounting for environmental extremes, and capturing how organisms experience the environment. Intertidal mussel data illustrate biologically important aspects of environmental variability. We then discuss key challenges in translating environmental conditions into organismal performance including accounting for the varied timescales of physiological processes, for responses to environmental fluctuations including the onset of stress and other thresholds, and for how environmental sensitivities vary across lifecycles. We call for the creation of phenotypic databases to parameterize forecasting models and advocate for improved sharing of model code and data for model testing. We conclude with challenges in organismal biology that must be solved to improve forecasts over the next decade.acclimation, biophysical models, ecological forecasting, extremes, microclimate, spatial and temporal variability.

Accelerated Weathering of Waste Glass at 90°C with the Pressurized Unsaturated Flow (PUF) Apparatus: Implications for Predicting Glass Corrosion with a Reactive Transport Model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pierce, Eric M.; Bacon, Diana H.

2009-09-21

The interest in the long-term durability of waste glass stems from the need to predict radionuclide release rates from the corroding glass over geologic time-scales. Several long-term test methods have been developed to accelerate the glass-water reaction [drip test, vapor hydration test, product consistency test-B, and pressurized unsaturated flow (PUF)]. Currently, the PUF test is the only method that can mimic the unsaturated hydraulic properties expected in a subsurface disposal facility and simultaneously monitor the glass-water reaction. PUF tests are being conducted to accelerate the weathering of glass and validate the model parameters being used to predict long-term glass behavior.more » One dimensional reactive chemical transport simulations of glass dissolution and secondary phase formation during a 1.5-year long PUF experiment was conducted with the subsurface transport over reactive multi-phases (STORM) code. Results show that parameterization of the computer model by combining direct laboratory measurements and thermodynamic data provides an integrated approach to predicting glass behavior over geologic-time scales.« less

Iron control on global productivity: an efficient inverse model of the ocean's coupled phosphate and iron cycles.

NASA Astrophysics Data System (ADS)

Pasquier, B.; Holzer, M.; Frants, M.

2016-02-01

We construct a data-constrained mechanistic inverse model of the ocean's coupled phosphorus and iron cycles. The nutrient cycling is embedded in a data-assimilated steady global circulation. Biological nutrient uptake is parameterized in terms of nutrient, light, and temperature limitations on growth for two classes of phytoplankton that are not transported explicitly. A matrix formulation of the discretized nutrient tracer equations allows for efficient numerical solutions, which facilitates the objective optimization of the key biogeochemical parameters. The optimization minimizes the misfit between the modelled and observed nutrient fields of the current climate. We systematically assess the nonlinear response of the biological pump to changes in the aeolian iron supply for a variety of scenarios. Specifically, Green-function techniques are employed to quantify in detail the pathways and timescales with which those perturbations are propagated throughout the world oceans, determining the global teleconnections that mediate the response of the global ocean ecosystem. We confirm previous findings from idealized studies that increased iron fertilization decreases biological production in the subtropical gyres and we quantify the counterintuitive and asymmetric response of global productivity to increases and decreases in the aeolian iron supply.

Spatial regression analysis on 32 years of total column ozone data

NASA Astrophysics Data System (ADS)

Knibbe, J. S.; van der A, R. J.; de Laat, A. T. J.

2014-08-01

Multiple-regression analyses have been performed on 32 years of total ozone column data that was spatially gridded with a 1 × 1.5° resolution. The total ozone data consist of the MSR (Multi Sensor Reanalysis; 1979-2008) and 2 years of assimilated SCIAMACHY (SCanning Imaging Absorption spectroMeter for Atmospheric CHartographY) ozone data (2009-2010). The two-dimensionality in this data set allows us to perform the regressions locally and investigate spatial patterns of regression coefficients and their explanatory power. Seasonal dependencies of ozone on regressors are included in the analysis. A new physically oriented model is developed to parameterize stratospheric ozone. Ozone variations on nonseasonal timescales are parameterized by explanatory variables describing the solar cycle, stratospheric aerosols, the quasi-biennial oscillation (QBO), El Niño-Southern Oscillation (ENSO) and stratospheric alternative halogens which are parameterized by the effective equivalent stratospheric chlorine (EESC). For several explanatory variables, seasonally adjusted versions of these explanatory variables are constructed to account for the difference in their effect on ozone throughout the year. To account for seasonal variation in ozone, explanatory variables describing the polar vortex, geopotential height, potential vorticity and average day length are included. Results of this regression model are compared to that of a similar analysis based on a more commonly applied statistically oriented model. The physically oriented model provides spatial patterns in the regression results for each explanatory variable. The EESC has a significant depleting effect on ozone at mid- and high latitudes, the solar cycle affects ozone positively mostly in the Southern Hemisphere, stratospheric aerosols affect ozone negatively at high northern latitudes, the effect of QBO is positive and negative in the tropics and mid- to high latitudes, respectively, and ENSO affects ozone negatively between 30° N and 30° S, particularly over the Pacific. The contribution of explanatory variables describing seasonal ozone variation is generally large at mid- to high latitudes. We observe ozone increases with potential vorticity and day length and ozone decreases with geopotential height and variable ozone effects due to the polar vortex in regions to the north and south of the polar vortices. Recovery of ozone is identified globally. However, recovery rates and uncertainties strongly depend on choices that can be made in defining the explanatory variables. The application of several trend models, each with their own pros and cons, yields a large range of recovery rate estimates. Overall these results suggest that care has to be taken in determining ozone recovery rates, in particular for the Antarctic ozone hole.

Immediate effects of different types of stretching exercises on badminton jump smash.

PubMed

Jang, Hwi S; Kim, Daeho; Park, Jihong

2018-01-01

Since different types of stretching exercises may alter athletic performance, we compared the effects of three types of stretching exercises on badminton jump smash. Sixteen male collegiate badminton players performed one of three different stretching exercises in a counterbalanced order on different days. Static stretching had seven typical stretches, while dynamic stretching involved nine dynamic movements, and resistance dynamic stretching was performed with weighted vests and dumbbells. Before and after each stretching exercise, subjects performed 20 trials of jump smashes. Dependent measurements were the jump heights during jump smashes, velocities of jump-smashed shuttlecocks, and drop point of jump-smashed shuttlecocks. To test the effects of each stretching exercise, we performed mixed model ANOVAs and calculated between-time effect sizes (ES). Each stretching exercise improved the jump heights during jump smashes (type main effect: F(2,75)=1.19, P=0.31; static stretching: 22.1%, P<0.01, ES=0.98; dynamic stretching: 30.1%, P<0.01, ES=1.49; resistance dynamic stretching: 17.7%, P=0.03, ES=0.98) and velocities of jump-smashed shuttlecocks (type main effect: F(2,75)=2.18, P=0.12; static stretching: 5.7%, P=0.61, ES=0.39; dynamic stretching: 3.4%, P=0.94, ES=0.28; resistance dynamic stretching: 6%, P=0.50, ES=0.66). However, there were no differences among the stretching exercises for any measurement. The drop point of jump-smashed shuttlecocks did not change (interaction: F(2,75)=0.88, P=0.42). All stretching exercises improved badminton jump smash performance, but we could not determine the best protocol. Since badminton requires high-speed movement and explosive force, we suggest performing dynamic stretching or resistance dynamic stretching.

Parameterizing deep convection using the assumed probability density function method

DOE PAGES

Storer, R. L.; Griffin, B. M.; Höft, J.; ...

2014-06-11

Due to their coarse horizontal resolution, present-day climate models must parameterize deep convection. This paper presents single-column simulations of deep convection using a probability density function (PDF) parameterization. The PDF parameterization predicts the PDF of subgrid variability of turbulence, clouds, and hydrometeors. That variability is interfaced to a prognostic microphysics scheme using a Monte Carlo sampling method. The PDF parameterization is used to simulate tropical deep convection, the transition from shallow to deep convection over land, and mid-latitude deep convection. These parameterized single-column simulations are compared with 3-D reference simulations. The agreement is satisfactory except when the convective forcing ismore » weak. The same PDF parameterization is also used to simulate shallow cumulus and stratocumulus layers. The PDF method is sufficiently general to adequately simulate these five deep, shallow, and stratiform cloud cases with a single equation set. This raises hopes that it may be possible in the future, with further refinements at coarse time step and grid spacing, to parameterize all cloud types in a large-scale model in a unified way.« less

Parameterizing deep convection using the assumed probability density function method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Storer, R. L.; Griffin, B. M.; Höft, J.

2015-01-06

Due to their coarse horizontal resolution, present-day climate models must parameterize deep convection. This paper presents single-column simulations of deep convection using a probability density function (PDF) parameterization. The PDF parameterization predicts the PDF of subgrid variability of turbulence, clouds, and hydrometeors. That variability is interfaced to a prognostic microphysics scheme using a Monte Carlo sampling method.The PDF parameterization is used to simulate tropical deep convection, the transition from shallow to deep convection over land, and midlatitude deep convection. These parameterized single-column simulations are compared with 3-D reference simulations. The agreement is satisfactory except when the convective forcing is weak.more » The same PDF parameterization is also used to simulate shallow cumulus and stratocumulus layers. The PDF method is sufficiently general to adequately simulate these five deep, shallow, and stratiform cloud cases with a single equation set. This raises hopes that it may be possible in the future, with further refinements at coarse time step and grid spacing, to parameterize all cloud types in a large-scale model in a unified way.« less

Parameterizing deep convection using the assumed probability density function method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Storer, R. L.; Griffin, B. M.; Hoft, Jan

2015-01-06

Due to their coarse horizontal resolution, present-day climate models must parameterize deep convection. This paper presents single-column simulations of deep convection using a probability density function (PDF) parameterization. The PDF parameterization predicts the PDF of subgrid variability of turbulence, clouds, and hydrometeors. That variability is interfaced to a prognostic microphysics scheme using a Monte Carlo sampling method.The PDF parameterization is used to simulate tropical deep convection, the transition from shallow to deep convection over land, and mid-latitude deep convection.These parameterized single-column simulations are compared with 3-D reference simulations. The agreement is satisfactory except when the convective forcing is weak. Themore » same PDF parameterization is also used to simulate shallow cumulus and stratocumulus layers. The PDF method is sufficiently general to adequately simulate these five deep, shallow, and stratiform cloud cases with a single equation set. This raises hopes that it may be possible in the future, with further refinements at coarse time step and grid spacing, to parameterize all cloud types in a large-scale model in a unified way.« less

Solar Variability from 240 to 1750 nm in Terms of Faculae Brightening and Sunspot Darkening from SCIAMACHY

NASA Astrophysics Data System (ADS)

Pagaran, J.; Weber, M.; Burrows, J.

2009-08-01

The change of spectral decomposition of the total radiative output on various timescales of solar magnetic activity is of large interest to terrestrial and solar-stellar atmosphere studies. Starting in 2002, SCIAMACHY was the first satellite instrument to observe daily solar spectral irradiance (SSI) continuously from 230 nm (UV) to 1750 nm (near-infrared; near-IR). In order to address the question of how much UV, visible (vis), and IR spectral regions change on 27 day and 11 year timescales, we parameterize short-term SSI variations in terms of faculae brightening (Mg II index) and sunspot darkening (photometric sunspot index) proxies. Although spectral variations above 300 nm are below 1% and, therefore, well below the accuracy of absolute radiometric calibration, relative accuracy for short-term changes is shown to be in the per mill range. This enables us to derive short-term spectral irradiance variations from the UV to the near-IR. During Halloween solar storm in 2003 with a record high sunspot area, we observe a reduction of 0.3% in the near-IR to 0.5% in the vis and near-UV. This is consistent with a 0.4% reduction in total solar irradiance (TSI). Over an entire 11 year solar cycle, SSI variability covering simultaneously the UV, vis, and IR spectral regions have not been directly observed so far. Using variations of solar proxies over solar cycle 23, solar cycle spectral variations have been estimated using scaling factors that best matched short-term variations of SCIAMACHY. In the 300-400 nm region, which strongly contributes to TSI solar cycle change, a contribution of 34% is derived from SCIAMACHY observations, which is lower than the reported values from SUSIM satellite data and the empirical SATIRE model. The total UV contribution (below 400 nm) to TSI solar cycle variations is estimated to be 55%.

SOLAR VARIABILITY FROM 240 TO 1750 nm IN TERMS OF FACULAE BRIGHTENING AND SUNSPOT DARKENING FROM SCIAMACHY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pagaran, J.; Weber, M.; Burrows, J.

2009-08-01

The change of spectral decomposition of the total radiative output on various timescales of solar magnetic activity is of large interest to terrestrial and solar-stellar atmosphere studies. Starting in 2002, SCIAMACHY was the first satellite instrument to observe daily solar spectral irradiance (SSI) continuously from 230 nm (UV) to 1750 nm (near-infrared; near-IR). In order to address the question of how much UV, visible (vis), and IR spectral regions change on 27 day and 11 year timescales, we parameterize short-term SSI variations in terms of faculae brightening (Mg II index) and sunspot darkening (photometric sunspot index) proxies. Although spectral variationsmore » above 300 nm are below 1% and, therefore, well below the accuracy of absolute radiometric calibration, relative accuracy for short-term changes is shown to be in the per mill range. This enables us to derive short-term spectral irradiance variations from the UV to the near-IR. During Halloween solar storm in 2003 with a record high sunspot area, we observe a reduction of 0.3% in the near-IR to 0.5% in the vis and near-UV. This is consistent with a 0.4% reduction in total solar irradiance (TSI). Over an entire 11 year solar cycle, SSI variability covering simultaneously the UV, vis, and IR spectral regions have not been directly observed so far. Using variations of solar proxies over solar cycle 23, solar cycle spectral variations have been estimated using scaling factors that best matched short-term variations of SCIAMACHY. In the 300-400 nm region, which strongly contributes to TSI solar cycle change, a contribution of 34% is derived from SCIAMACHY observations, which is lower than the reported values from SUSIM satellite data and the empirical SATIRE model. The total UV contribution (below 400 nm) to TSI solar cycle variations is estimated to be 55%.« less

A Microphysics-Based Black Carbon Aging Scheme in a Global Chemical Transport Model: Constraints from HIPPO Observations

NASA Astrophysics Data System (ADS)

He, C.; Li, Q.; Liou, K. N.; Qi, L.; Tao, S.; Schwarz, J. P.

2015-12-01

Black carbon (BC) aging significantly affects its distributions and radiative properties, which is an important uncertainty source in estimating BC climatic effects. Global models often use a fixed aging timescale for the hydrophobic-to-hydrophilic BC conversion or a simple parameterization. We have developed and implemented a microphysics-based BC aging scheme that accounts for condensation and coagulation processes into a global 3-D chemical transport model (GEOS-Chem). Model results are systematically evaluated by comparing with the HIPPO observations across the Pacific (67°S-85°N) during 2009-2011. We find that the microphysics-based scheme substantially increases the BC aging rate over source regions as compared with the fixed aging timescale (1.2 days), due to the condensation of sulfate and secondary organic aerosols (SOA) and coagulation with pre-existing hydrophilic aerosols. However, the microphysics-based scheme slows down BC aging over Polar regions where condensation and coagulation are rather weak. We find that BC aging is primarily dominated by condensation process that accounts for ~75% of global BC aging, while the coagulation process is important over source regions where a large amount of pre-existing aerosols are available. Model results show that the fixed aging scheme tends to overestimate BC concentrations over the Pacific throughout the troposphere by a factor of 2-5 at different latitudes, while the microphysics-based scheme reduces the discrepancies by up to a factor of 2, particularly in the middle troposphere. The microphysics-based scheme developed in this work decreases BC column total concentrations at all latitudes and seasons, especially over tropical regions, leading to large improvement in model simulations. We are presently analyzing the impact of this scheme on global BC budget and lifetime, quantifying its uncertainty associated with key parameters, and investigating the effects of heterogeneous chemical oxidation on BC aging.

Monitoring burned and unburned hillslopes from North Carolina to southern California: insights into hydrologic and geomorphic controls on disturbance-recovery cycles

NASA Astrophysics Data System (ADS)

Mirus, B. B.; Kean, J. W.; Smith, J. B.; Staley, D. M.; Wooten, R.; Cattanach, B.; Rengers, F. K.; McGuire, L.; Godt, J.; Lu, N.

2017-12-01

On steep hillslopes, vegetation often provides an important ecosystem function by preventing landsliding, debris flows, and floods, thereby protecting human lives and infrastructure. Disturbances that disrupt vegetation - from wildfire and forest clearing to landslides themselves - can abruptly alter hillslope hydrologic and geomorphic processes thereby increasing the threat of these natural hazards. Two major challenges from a hazard assessment perspective are: (1) quantifying disturbance impacts on near-surface hydrologic responses, and (2) understanding the relevant processes and timescales associated with disturbance-recovery cycles. These challenges are complicated by the limited availability of long-term monitoring in pre- and post-disturbance environments. Therefore, many tools designed to provide rapid situational awareness and improve disaster preparedness and response rely on temporally invariant parameterization or locally derived empirical relations that are not necessarily transferrable across different geologic or climatic settings. Here we examine hillslope hydrologic response in landslide-prone terrain across the continental US, from the West Coast to Appalachia, to explore these issues related to disturbance-recovery cycles. Wildfire is a recurring disturbance along the actively uplifting mountains in semi-arid southern California, and heavy winter storms arriving from the Pacific are frequently able to produce debris flows in recently burned areas. Although wildfire is less common in the much wetter Cascades and Coast Ranges of Oregon and Washington, frequent landslides and forest clearing disturbances also influence hillslope hydrology and slope stability. In contrast, the recent wildfires in Tennessee, Georgia, and North Carolina have highlighted critical knowledge gaps related to post-fire hydrology and natural hazards in the geologically stable and humid sub-tropical southeastern US, where severe wildfires are less common than other disturbances. Our continuous monitoring from several burned and unburned hillslopes across these diverse geologic and climatic settings reveals variations in the disturbance impacts and recovery timescales, as well as the need for further monitoring, modeling, and synthesis across regions and scales.

Characterization and Modeling of Atmospheric Flow Within and Above Plant Canopies

NASA Astrophysics Data System (ADS)

Souza Freire Grion, Livia

The turbulent flow within and above plant canopies is responsible for the exchange of momentum, heat, gases and particles between vegetation and the atmosphere. Turbulence is also responsible for the mixing of air inside the canopy, playing an important role in chemical and biophysical processes occurring in the plants' environment. In the last fifty years, research has significantly advanced the understanding of and ability to model the flow field within and above the canopy, but important issues remain unsolved. In this work, we focus on (i) the estimation of turbulent mixing timescales within the canopy from field data; and (ii) the development of new computationally efficient modeling approaches for the coupled canopy-atmosphere flow field. The turbulent mixing timescale represents how quickly turbulence creates a well-mixed environment within the canopy. When the mixing timescale is much smaller than the timescale of other relevant processes (e.g. chemical reactions, deposition), the system can be assumed to be well-mixed and detailed modeling of turbulence is not critical to predict the system evolution. Conversely, if the mixing timescale is comparable or larger than the other timescales, turbulence becomes a controlling factor for the concentration of the variables involved; hence, turbulence needs to be taken into account when studying and modeling such processes. In this work, we used a combination of ozone concentration and high-frequency velocity data measured within and above the canopy in the Amazon rainforest to characterize turbulent mixing. The eddy diffusivity parameter (used as a proxy for mixing efficiency) was applied in a simple theoretical model of one-dimensional diffusion, providing an estimate of turbulent mixing timescales as a function of height within the canopy and time-of-day. Results showed that, during the day, the Amazon rainforest is characterized by well-mixed conditions with mixing timescales smaller than thirty minutes in the upper-half of the canopy, and partially mixed conditions in the lower half of the canopy. During the night, most of the canopy (except for the upper 20%) is either partially or poorly mixed, resulting in mixing timescales of up to several hours. For the specific case of ozone, the mixing timescales observed during the day are much lower than the chemical and deposition timescales, whereas chemical processes and turbulence have comparable timescales during the night. In addition, the high day-to-day variability in mixing conditions and the fast increase in mixing during the morning transition period indicate that turbulence within the canopy needs to be properly investigated and modeled in many studies involving plant-atmosphere interactions. Motivated by the findings described above, this work proposes and tests a new approach for modeling canopy flows. Typically, vertical profiles of flow statistics are needed to represent canopy-atmosphere exchanges in chemical and biophysical processes happening within the canopy. Current single-column models provide only steady-state (equilibrium) profiles, and rely on closure assumptions that do not represent the dominant non-local turbulent fluxes present in canopy flows. We overcome these issues by adapting the one-dimensional turbulent (ODT) model to represent atmospheric flows from the ground up to the top of the atmospheric boundary layer (ABL). The ODT model numerically resolves the one-dimensional diffusion equation along a vertical line (representing a horizontally homogeneous ABL column), and the presence of three-dimensional turbulence is added through the effect of stochastic eddies. Simulations of ABL without canopy were performed for different atmospheric stabilities and a diurnal cycle, to test the capabilities of this modeling approach in representing unsteady flows with strong non-local transport. In addition, four different types of canopies were simulated, one of them including the transport of scalar with a point source located inside the canopy. The comparison of all simulations with theory and field data provided satisfactory results. The main advantages of using ODT compared to typical 1D canopy-flow models are the ability to represent the coupled canopy-ABL flow with one single modeling approach, the presence of non-local turbulent fluxes, the ability to simulate transient conditions, the straightforward representation of multiple scalar fields, and the presence of only one adjustable parameter (as opposed to the several adjustable constants and boundary conditions needed for other modeling approaches). The results obtained with ODT as a stand-alone model motivated its use as a surface parameterization for Large-Eddy Simulation (LES). In this two-way coupling between LES and ODT, the former is used to simulate the ABL in a case where a canopy is present but cannot be resolved by the LES (i.e., the LES first vertical grid point is above the canopy). ODT is used to represent the flow field between the ground and the first LES grid point, including the region within and just above the canopy. In this work, we tested the ODT-LES model for three different types of canopies and obtained promising results. Although more work is needed in order to improve first and second-order statistics within the canopy (i.e. in the ODT domain), the results obtained for the flow statistics in the LES domain and for the third order statistics in the ODT domain demonstrate that the ODT-LES model is capable of capturing some important features of the canopy-atmosphere interaction. This new surface superparameterization approach using ODT provides a new alternative for simulations that require complex interactions between the flow field and near-surface processes (e.g. sand and snow drift, waves over water surfaces) and can potentially be extended to other large-scale models, such as mesoscale and global circulation models.

Glass transition-related thermorheological complexity in polystyrene melts

NASA Astrophysics Data System (ADS)

Lin, Y.-H.

2007-11-01

The relaxation-modulus G(t) functional forms covering the whole time range are given by incorporating a stretched exponential for the structural- (glassy-) relaxation process into the extended reptation theory (ERT; for entangled systems) or the Rouse theory (for entanglement-free systems). The creep compliance J(t) curves of two entangled (A and B) and one entanglement-free (C) polystyrene samples (Plazek) as well as the viscoelastic spectra G*(ω) of four entanglement-free polystyrene samples (Inoue et al) have been quantitatively analyzed in terms of the given G(t) functional forms. In such quantitatively successful analyses, the ERT or the Rouse theory works as the frame of reference in both the line shape and timescale. The thermorheological complexity in the J(t) curves is explained naturally and precisely by the temperature dependence of the energetic-interaction-derived structural relaxation being stronger than that of the entropic ERT or Rouse dynamics in a simple way. Structural-relaxation times τS (= 18s'K') of all the studied samples are equally well separated into two decoupled quantities: the structural-growth parameter s' and the frictional factor K' (for the Rouse-Mooney or Rouse modes of motion). The separation is fundamentally a clean-cut process: s' is determined entirely by the line shape of J(t) or G*(ω) while K' is calculated from the timescale shifting factor obtained from the superposition of the calculated curves onto the measured. The glassy-relaxation strength AGf and the stretching parameter β extracted from the J(t) and G*(ω) results over the glassy-relaxation region are in good agreement. The glass-transition temperature Tg is defined as corresponding to τS = 1000 s for all the studied samples. The τS, s' and K' data points of samples A, B and C extracted from their J(t) curves individually fall closely on the same curves when expressed as a function of ΔT = T-Tg, revealing a Tg-related universality within the polystyrene system, entangled or not. The revealed universality confirms the previously derived conclusion that the ERT and the Rouse theory have the same footing at the Rouse-segmental level. Representing important physical features of the universality, the length-scale of the structural relaxation increases as ΔT diminishes and reaches the value of ~3 nm at ΔT = 0 (or at Tg) for all three samples, A, B and C. Extracted from the G*(ω) results, the τS, s' and K' data of samples with molecular weights just below and well below entanglement molecular weight Me (13 500) are found to deviate more from the respective universal curves with decreasing molecular weight. Deviation is estimated to start occurring at Mw = 12 000.

Perspectives for short timescale variability studies with Gaia

NASA Astrophysics Data System (ADS)

Roelens, M.; Eyer, L.; Mowlavi, N.; Lecoeur-Taïbi, I.; Rimoldini, L.; Blanco-Cuaresma, S.; Palaversa, L.; Süveges, M.; Charnas, J.; Wevers, T.

2017-12-01

We assess the potential of Gaia for detecting and characterizing short timescale variables, i.e. at timescale from a few seconds to a dozen hours, through extensive light-curve simulations for various short timescale variable types, including both periodic and non-periodic variability. We evidence that the variogram analysis applied to Gaia photometry should enable to detect such fast variability phenomena, down to amplitudes of a few millimagnitudes, with limited contamination from longer timescale variables or constant sources. This approach also gives valuable information on the typical timescale(s) of the considered variation, which could complement results of classical period search methods, and help prepare ground-based follow-up of the Gaia short timescale candidates.

Turbulent Mixing in Gravity Currents with Transverse Shear

NASA Astrophysics Data System (ADS)

White, Brian; Helfrich, Karl; Scotti, Alberto

2010-11-01

A parallel flow with horizontal shear and horizontal density gradient undergoes an intensification of the shear by gravitational tilting and stretching, rapidly breaking down into turbulence. Such flows have the potential for substantial mixing in estuaries and the coastal ocean. We present high-resolution numerical results for the mixing efficiency of these flows, which can be viewed as gravity currents with transverse shear, and contrast them with the well-studied case of stably stratified, homogeneous turbulence (uniform vertical density and velocity gradients). For a sheared gravity current, the buoyancy flux, turbulent Reynolds stress, and dissipation are well out of equilibrium. The total kinetic energy first increases as potential energy is transferred to the gravity current, but rapidly decays once turbulence sets in. Despite the non-equilibrium character, mixing efficiencies are slightly higher but qualitatively similar to homogeneous stratified turbulence. Efficiency decreases in the highly energetic regime where the dissipation rate is large compared with viscosity and stratification, ɛ/(νN^2)>100, further declining as turbulence decays and kinetic energy dissipation dominates the buoyancy flux. In general, the mixing rate, parameterized by a turbulent eddy diffusivity, increases with the strength of the transverse shear.

Global model comparison of heterogeneous ice nucleation parameterizations in mixed phase clouds

NASA Astrophysics Data System (ADS)

Yun, Yuxing; Penner, Joyce E.

2012-04-01

A new aerosol-dependent mixed phase cloud parameterization for deposition/condensation/immersion (DCI) ice nucleation and one for contact freezing are compared to the original formulations in a coupled general circulation model and aerosol transport model. The present-day cloud liquid and ice water fields and cloud radiative forcing are analyzed and compared to observations. The new DCI freezing parameterization changes the spatial distribution of the cloud water field. Significant changes are found in the cloud ice water fraction and in the middle cloud fractions. The new DCI freezing parameterization predicts less ice water path (IWP) than the original formulation, especially in the Southern Hemisphere. The smaller IWP leads to a less efficient Bergeron-Findeisen process resulting in a larger liquid water path, shortwave cloud forcing, and longwave cloud forcing. It is found that contact freezing parameterizations have a greater impact on the cloud water field and radiative forcing than the two DCI freezing parameterizations that we compared. The net solar flux at top of atmosphere and net longwave flux at the top of the atmosphere change by up to 8.73 and 3.52 W m-2, respectively, due to the use of different DCI and contact freezing parameterizations in mixed phase clouds. The total climate forcing from anthropogenic black carbon/organic matter in mixed phase clouds is estimated to be 0.16-0.93 W m-2using the aerosol-dependent parameterizations. A sensitivity test with contact ice nuclei concentration in the original parameterization fit to that recommended by Young (1974) gives results that are closer to the new contact freezing parameterization.

Effects of Static and Dynamic Stretching on the Isokinetic Peak Torques and Electromyographic Activities of the Antagonist Muscles

PubMed Central

Serefoglu, Abdullah; Sekir, Ufuk; Gür, Hakan; Akova, Bedrettin

2017-01-01

The aim of this study was to investigate if static and dynamic stretching exercises of the knee muscles (quadriceps and hamstring muscles) have any effects on concentric and eccentric isokinetic peak torques and electromyographic amplitudes (EMG) of the antagonist muscles. Twenty healthy male athletes (age between 18-30 years) voluntarily participated in this study. All of the subjects visited the laboratory to complete the following intervention in a randomized order on 5 separate days; (a) non-stretching (control), (b) static stretching of the quadriceps muscles, (c) static stretching of the hamstring muscles, (d) dynamic stretching of the quadriceps muscles, and (e) dynamic stretching of the hamstring muscles. Static stretching exercises either for the quadriceps or the hamstring muscles were carried out at the standing and sitting positions. Subjects performed four successive repetitions of each stretching exercises for 30 seconds in both stretching positions. Similar to static stretching exercises two different stretching modes were designed for dynamic stretching exercises. Concentric and eccentric isokinetic peak torque for the non-stretched antagonist quadriceps or hamstring muscles at angular velocities of 60°/sec and 240°/sec and their concurrent electromyographic (EMG) activities were measured before and immediately after the intervention. Isokinetic peak torques of the non-stretched agonist hamstring and quadriceps muscles did not represent any significant (p > 0.05) differences following static and dynamic stretching of the antagonist quadriceps and hamstring muscles, respectively. Similarly, the EMG activities of the agonist muscles exhibited no significant alterations (p > 0.05) following both stretching exercises of the antagonist muscles. According to the results of the present study it is possible to state that antagonist stretching exercises either in the static or dynamic modes do not affect the isokinetic peak torques and the EMG activities of the non-stretched agonist quadriceps or hamstring muscles. Key points The effects of dynamic stretching of the antagonist muscles on strength performance are unknown. We showed that both static and dynamic stretching of the antagonist muscle does not influence strength and EMG activities in the agonist muscles. Further research should focus on the effects of antagonist stretching using other techniques like PNF or ballistic stretching and/or different volumes of stretching. PMID:28344445

Neural effects of muscle stretching on the spinal reflexes in multiple lower-limb muscles.

PubMed

Masugi, Yohei; Obata, Hiroki; Inoue, Daisuke; Kawashima, Noritaka; Nakazawa, Kimitaka

2017-01-01

While previous studies have shown that muscle stretching suppresses monosynaptic spinal reflex excitability in stretched muscles, its effects on non-stretched muscles is still largely unknown. The purpose of this study was to examine the effects of muscle stretching on monosynaptic spinal reflex in non-stretched muscles. Ten healthy male subjects participated in this study. Muscle stretching of the right triceps surae muscle was performed using a motor torque device for 1 minute. Three different dorsiflexion torques (at approximately 5, 10, and 15 Nm) were applied during muscle stretching. Spinal reflexes evoked by transcutaneous spinal cord stimulation were recorded in both the lower-limb muscles before, during, and at 0 and 5 min following muscle stretching. The amplitudes of the spinal reflexes in both the stretched and non-stretched muscles in the right (ipsilateral) leg were smaller during stretching compared to before, and at 0 and 5 min after stretching. Furthermore, the degree of reduction in the amplitude of the spinal reflexes in the right (ipsilateral) leg muscles increased significantly as the dorsiflexion torque (i.e., stretching of the right triceps surae muscles) increased. In contrast, reduction in the amplitude of the spinal reflexes with increasing dorsiflexion torque was not seen in the left (contralateral) leg muscles. Our results clearly indicate that muscle stretching has inhibitory effects on monosynaptic spinal reflexes, not only in stretched muscles, but also in non-stretched muscles of the ipsilateral leg.

Neural effects of muscle stretching on the spinal reflexes in multiple lower-limb muscles

PubMed Central

Obata, Hiroki; Inoue, Daisuke; Kawashima, Noritaka; Nakazawa, Kimitaka

2017-01-01

While previous studies have shown that muscle stretching suppresses monosynaptic spinal reflex excitability in stretched muscles, its effects on non-stretched muscles is still largely unknown. The purpose of this study was to examine the effects of muscle stretching on monosynaptic spinal reflex in non-stretched muscles. Ten healthy male subjects participated in this study. Muscle stretching of the right triceps surae muscle was performed using a motor torque device for 1 minute. Three different dorsiflexion torques (at approximately 5, 10, and 15 Nm) were applied during muscle stretching. Spinal reflexes evoked by transcutaneous spinal cord stimulation were recorded in both the lower-limb muscles before, during, and at 0 and 5 min following muscle stretching. The amplitudes of the spinal reflexes in both the stretched and non-stretched muscles in the right (ipsilateral) leg were smaller during stretching compared to before, and at 0 and 5 min after stretching. Furthermore, the degree of reduction in the amplitude of the spinal reflexes in the right (ipsilateral) leg muscles increased significantly as the dorsiflexion torque (i.e., stretching of the right triceps surae muscles) increased. In contrast, reduction in the amplitude of the spinal reflexes with increasing dorsiflexion torque was not seen in the left (contralateral) leg muscles. Our results clearly indicate that muscle stretching has inhibitory effects on monosynaptic spinal reflexes, not only in stretched muscles, but also in non-stretched muscles of the ipsilateral leg. PMID:28662201

Evaluation of Warm-Rain Microphysical Parameterizations in Cloudy Boundary Layer Transitions

NASA Astrophysics Data System (ADS)

Nelson, K.; Mechem, D. B.

2014-12-01

Common warm-rain microphysical parameterizations used for marine boundary layer (MBL) clouds are either tuned for specific cloud types (e.g., the Khairoutdinov and Kogan 2000 parameterization, "KK2000") or are altogether ill-posed (Kessler 1969). An ideal microphysical parameterization should be "unified" in the sense of being suitable across MBL cloud regimes that include stratocumulus, cumulus rising into stratocumulus, and shallow trade cumulus. The recent parameterization of Kogan (2013, "K2013") was formulated for shallow cumulus but has been shown in a large-eddy simulation environment to work quite well for stratocumulus as well. We report on our efforts to implement and test this parameterization into a regional forecast model (NRL COAMPS). Results from K2013 and KK2000 are compared with the operational Kessler parameterization for a 5-day period of the VOCALS-REx field campaign, which took place over the southeast Pacific. We focus on both the relative performance of the three parameterizations and also on how they compare to the VOCALS-REx observations from the NOAA R/V Ronald H. Brown, in particular estimates of boundary-layer depth, liquid water path (LWP), cloud base, and area-mean precipitation rate obtained from C-band radar.

A unified parameterization of clouds and turbulence using CLUBB and subcolumns in the Community Atmosphere Model

DOE PAGES

Thayer-Calder, K.; Gettelman, A.; Craig, C.; ...

2015-06-30

Most global climate models parameterize separate cloud types using separate parameterizations. This approach has several disadvantages, including obscure interactions between parameterizations and inaccurate triggering of cumulus parameterizations. Alternatively, a unified cloud parameterization uses one equation set to represent all cloud types. Such cloud types include stratiform liquid and ice cloud, shallow convective cloud, and deep convective cloud. Vital to the success of a unified parameterization is a general interface between clouds and microphysics. One such interface involves drawing Monte Carlo samples of subgrid variability of temperature, water vapor, cloud liquid, and cloud ice, and feeding the sample points into amore » microphysics scheme.This study evaluates a unified cloud parameterization and a Monte Carlo microphysics interface that has been implemented in the Community Atmosphere Model (CAM) version 5.3. Results describing the mean climate and tropical variability from global simulations are presented. The new model shows a degradation in precipitation skill but improvements in short-wave cloud forcing, liquid water path, long-wave cloud forcing, precipitable water, and tropical wave simulation. Also presented are estimations of computational expense and investigation of sensitivity to number of subcolumns.« less

A unified parameterization of clouds and turbulence using CLUBB and subcolumns in the Community Atmosphere Model

DOE PAGES

Thayer-Calder, Katherine; Gettelman, A.; Craig, Cheryl; ...

2015-12-01

Most global climate models parameterize separate cloud types using separate parameterizations.This approach has several disadvantages, including obscure interactions between parameterizations and inaccurate triggering of cumulus parameterizations. Alternatively, a unified cloud parameterization uses one equation set to represent all cloud types. Such cloud types include stratiform liquid and ice cloud, shallow convective cloud, and deep convective cloud. Vital to the success of a unified parameterization is a general interface between clouds and microphysics. One such interface involves drawing Monte Carlo samples of subgrid variability of temperature, water vapor, cloud liquid, and cloud ice, and feeding the sample points into a microphysicsmore » scheme. This study evaluates a unified cloud parameterization and a Monte Carlo microphysics interface that has been implemented in the Community Atmosphere Model (CAM) version 5.3. Results describing the mean climate and tropical variability from global simulations are presented. In conclusion, the new model shows a degradation in precipitation skill but improvements in short-wave cloud forcing, liquid water path, long-wave cloud forcing, perceptible water, and tropical wave simulation. Also presented are estimations of computational expense and investigation of sensitivity to number of subcolumns.« less

Immediate effect of passive and active stretching on hamstrings flexibility: a single-blinded randomized control trial.

PubMed

Nishikawa, Yuichi; Aizawa, Junya; Kanemura, Naohiko; Takahashi, Tetsuya; Hosomi, Naohisa; Maruyama, Hirofumi; Kimura, Hiroaki; Matsumoto, Masayasu; Takayanagi, Kiyomi

2015-10-01

[Purpose] This study compared the efficacy of passive and active stretching techniques on hamstring flexibility. [Subjects] Fifty-four healthy young subjects were randomly assigned to one of three groups (2 treatment groups and 1 control group). [Methods] Subjects in the passive stretching group had their knees extended by an examiner while lying supine 90° of hip flexion. In the same position, subjects in the active stretching group extended their knees. The groups performed 3 sets of the assigned stretch, with each stretch held for 10 seconds at the point where tightness in the hamstring muscles was felt. Subjects in the control group did not perform stretching. Before and immediately after stretching, hamstring flexibility was assessed by a blinded assessor, using the active knee-extension test. [Results] After stretching, there was a significant improvement in the hamstring flexibilities of the active and passive stretching groups compared with the control group. Furthermore, the passive stretching group showed significantly greater improvement in hamstring flexibility than the active stretching group. [Conclusion] Improvement in hamstring flexibility measured by the active knee-extension test was achieved by both stretching techniques; however, passive stretching was more effective than active stretching at achieving an immediate increase in hamstring flexibility.

Acute effects of constant torque and constant angle stretching on the muscle and tendon tissue properties.

PubMed

Konrad, Andreas; Budini, Francesco; Tilp, Markus

2017-08-01

Static stretching induces acute structural changes of the muscle-tendon unit (MTU) that are related to the intensity or duration of stretching. It has been reported that stretching with a constant torque (CT) leads to greater joint range of motion changes than stretching with a constant angle (CA). Whether or not this difference is due to different structural changes of the MTUs of the lower leg and ankle plantar flexors is not known. Therefore, the purpose of this study was to compare the acute effects of single CA and CT stretching on various muscle and tendon mechanical properties. Seventeen young, healthy volunteers were tested on two separate days using either CT or CA stretching (4 × 30 s each). Before and after stretching, dorsiflexion range of motion (RoM), passive resistive torque (PRT), and maximum voluntary contraction (MVC) were measured with a dynamometer. Ultrasonography of the medial gastrocnemius (GM) muscle-tendon junction (MTJ) displacement allowed us to determine the length changes in the tendon and muscle, respectively, and hence to calculate their stiffness. Maximum dorsiflexion increased while PRT, muscle-tendon stiffness, and muscle stiffness decreased following both CA and CT stretching. There was a greater increase in RoM following CT stretching compared to CA stretching. Moreover, the decline in PRT was greater during CT stretching compared to CA stretching. As expected, several functional adaptations (RoM, PRT) were different between CT and CA stretching due to the higher intensity of CT stretching. However, no structural differences in the adaptations to the stretching modalities could be detected. We suggest that the different functional adaptations between CA and CT stretching are the consequence of different adaptations in the perception of stretch and pain.

Acute Effects of Dynamic Stretching on Muscle Flexibility and Performance: An Analysis of the Current Literature.

PubMed

Opplert, Jules; Babault, Nicolas

2018-02-01

Stretching has long been used in many physical activities to increase range of motion (ROM) around a joint. Stretching also has other acute effects on the neuromuscular system. For instance, significant reductions in maximal voluntary strength, muscle power or evoked contractile properties have been recorded immediately after a single bout of static stretching, raising interest in other stretching modalities. Thus, the effects of dynamic stretching on subsequent muscular performance have been questioned. This review aimed to investigate performance and physiological alterations following dynamic stretching. There is a substantial amount of evidence pointing out the positive effects on ROM and subsequent performance (force, power, sprint and jump). The larger ROM would be mainly attributable to reduced stiffness of the muscle-tendon unit, while the improved muscular performance to temperature and potentiation-related mechanisms caused by the voluntary contraction associated with dynamic stretching. Therefore, if the goal of a warm-up is to increase joint ROM and to enhance muscle force and/or power, dynamic stretching seems to be a suitable alternative to static stretching. Nevertheless, numerous studies reporting no alteration or even performance impairment have highlighted possible mitigating factors (such as stretch duration, amplitude or velocity). Accordingly, ballistic stretching, a form of dynamic stretching with greater velocities, would be less beneficial than controlled dynamic stretching. Notwithstanding, the literature shows that inconsistent description of stretch procedures has been an important deterrent to reaching a clear consensus. In this review, we highlight the need for future studies reporting homogeneous, clearly described stretching protocols, and propose a clarified stretching terminology and methodology.

The Berkeley Out-of-Order Machine (BOOM): An Industry-Competitive, Synthesizable, Parameterized RISC-V Processor

DTIC Science & Technology

2015-06-13

The Berkeley Out-of-Order Machine (BOOM): An Industry- Competitive, Synthesizable, Parameterized RISC-V Processor Christopher Celio David A...Synthesizable, Parameterized RISC-V Processor Christopher Celio, David Patterson, and Krste Asanović University of California, Berkeley, California 94720...Order Machine BOOM is a synthesizable, parameterized, superscalar out- of-order RISC-V core designed to serve as the prototypical baseline processor

The acute effect of different stretching methods on sprint performance in taekwondo practitioners.

PubMed

Alemdaroğlu, Utku; Köklü, Yusuf; Koz, Mitat

2017-09-01

The purpose of this study was to compare the acute effects of different stretching types on sprint performance in taekwondo practitioners. Twelve male taekwondo practitioners performed stretching exercises using different types (ballistic, proprioceptive neuromuscular facilitation [PNF], static stretching) in a random order at three-day intervals; there was also a control condition involving no stretching exercises. The subjects performed 2 maximal 20-m sprints (with 10-m split times also recorded) with a recovery period of 1 minute immediately post stretching and at 5, 10, 15 and 20 minutes after stretching. They also performed these sprints before doing the stretching exercises. The study results showed that sprint times significantly increased after static stretching (10-m pre =1.84±0.07 s, 10-m post =1.89±0.08 s; 20-m pre =3.33±0.19 s, 20-m post= 3.38±0.2 s), PNF stretching (10-m pre =1.84±0.07 s, 10-m post =1.89±0.08 s; 20-m pre =3.33±0.19 s, 20-m post =3.38±0.20 s) and ballistic stretching (pre =1.84±0.08 s, post =1.86±0.07 s; 20-m pre =3.33±0.20 s, 20-m post =3.35±0.21 s) (P<0.05). In the static stretching condition, 10-m and 20-m sprint performance had fully returned to normal at 15 minutes after stretching. In the PNF stretching condition, 20-m sprint performance returned to normal levels at 15 minutes after stretching, while 10-m performance took 20 minutes to recover fully. In the ballistic stretching method, both 10-m and 20-m sprint performances had fully recovered at 5 minutes after stretching. It is therefore concluded that the acute effects of static, PNF and ballistic stretching may negatively affect sprint performance, although sprint performance is less affected after ballistic stretching than after the other stretching types. Therefore, it is not advisable to perform PNF or static stretching immediately before sprint performance.

Modelling temporal and large-scale spatial variability of soil respiration from soil water availability, temperature and vegetation productivity indices

NASA Astrophysics Data System (ADS)

Reichstein, M.; Rey, A.; Freibauer, A.; Tenhunen, J.; Valentini, R.; Soil Respiration Synthesis Team

2003-04-01

Field-chamber measurements of soil respiration from 17 different forest and shrubland sites in Europe and North America were summarized and analyzed with the goal to develop a model describing seasonal, inter-annual and spatial variability of soil respiration as affected by water availability, temperature and site properties. The analysis was performed at a daily and at a monthly time step. With the daily time step, the relative soil water content in the upper soil layer expressed as a fraction of field capacity was a good predictor of soil respiration at all sites. Among the site variables tested, those related to site productivity (e.g. leaf area index) correlated significantly with soil respiration, while carbon pool variables like standing biomass or the litter and soil carbon stocks did not show a clear relationship with soil respiration. Furthermore, it was evidenced that the effect of precipitation on soil respiration stretched beyond its direct effect via soil moisture. A general statistical non-linear regression model was developed to describe soil respiration as dependent on soil temperature, soil water content and site-specific maximum leaf area index. The model explained nearly two thirds of the temporal and inter-site variability of soil respiration with a mean absolute error of 0.82 µmol m-2 s-1. The parameterised model exhibits the following principal properties: 1) At a relative amount of upper-layer soil water of 16% of field capacity half-maximal soil respiration rates are reached. 2) The apparent temperature sensitivity of soil respiration measured as Q10 varies between 1 and 5 depending on soil temperature and water content. 3) Soil respiration under reference moisture and temperature conditions is linearly related to maximum site leaf area index. At a monthly time-scale we employed the approach by Raich et al. (2002, Global Change Biol. 8, 800-812) that used monthly precipitation and air temperature to globally predict soil respiration (T&P-model). While this model was able to explain some of the month-to-month variability of soil respiration, it failed to capture the inter-site variability, regardless whether the original or a new optimized model parameterization was used. In both cases, the residuals were strongly related to maximum site leaf area index. Thus, for a monthly time scale we developed a simple T&P&LAI-model that includes leaf area index as an additional predictor of soil respiration. This extended but still simple model performed nearly as well as the more detailed time-step model and explained 50 % of the overall and 65% of the site-to-site variability. Consequently, better estimates of globally distributed soil respiration should be obtained with the new model driven by satellite estimates of leaf area index.

Acute Effects of Three Different Stretching Protocols on the Wingate Test Performance

PubMed Central

Franco, Bruno L.; Signorelli, Gabriel R.; Trajano, Gabriel S.; Costa, Pablo B.; de Oliveira, Carlos G.

2012-01-01

The purpose of this study was to examine the acute effects of different stretching exercises on the performance of the traditional Wingate test (WT). Fifteen male participants performed five WT; one for familiarization (FT), and the remaining four after no stretching (NS), static stretching (SS), dynamic stretching (DS), and proprioceptive neuromuscular facilitation (PNF). Stretches were targeted for the hamstrings, quadriceps, and calf muscles. Peak power (PP), mean power (MP), and the time to reach PP (TP) were calculated. The MP was significantly lower when comparing the DS (7.7 ± 0.9 W/kg) to the PNF (7.3 ± 0.9 W/kg) condition (p < 0.05). For PP, significant differences were observed between more comparisons, with PNF stretching providing the lowest result. A consistent increase of TP was observed after all stretching exercises when compared to NS. The results suggest the type of stretching, or no stretching, should be considered by those who seek higher performance and practice sports that use maximal anaerobic power. Key points The mean power was significantly lower when comparing dynamic stretching.to proprioceptive neuromuscular facilitation. For peak power, significant differences were observed between more comparisons, with proprioceptive neuromuscular facilitation stretching providing the lowest result. A consistent increase of time to reach the peak was observed after all stretching exercises when compared to non-stretching. The type of stretching, or no stretching, should be considered by those who seek higher performance and practice sports that use maximal anaerobic power. PMID:24149116

Evaluation of different parameterizations of the spatial heterogeneity of subsurface storage capacity for hourly runoff simulation in boreal mountainous watershed

NASA Astrophysics Data System (ADS)

Hailegeorgis, Teklu T.; Alfredsen, Knut; Abdella, Yisak S.; Kolberg, Sjur

2015-03-01

Identification of proper parameterizations of spatial heterogeneity is required for precipitation-runoff models. However, relevant studies with a specific aim at hourly runoff simulation in boreal mountainous catchments are not common. We conducted calibration and evaluation of hourly runoff simulation in a boreal mountainous watershed based on six different parameterizations of the spatial heterogeneity of subsurface storage capacity for a semi-distributed (subcatchments hereafter called elements) and distributed (1 × 1 km2 grid) setup. We evaluated representation of element-to-element, grid-to-grid, and probabilistic subcatchment/subbasin, subelement and subgrid heterogeneities. The parameterization cases satisfactorily reproduced the streamflow hydrographs with Nash-Sutcliffe efficiency values for the calibration and validation periods up to 0.84 and 0.86 respectively, and similarly for the log-transformed streamflow up to 0.85 and 0.90. The parameterizations reproduced the flow duration curves, but predictive reliability in terms of quantile-quantile (Q-Q) plots indicated marked over and under predictions. The simple and parsimonious parameterizations with no subelement or no subgrid heterogeneities provided equivalent simulation performance compared to the more complex cases. The results indicated that (i) identification of parameterizations require measurements from denser precipitation stations than what is required for acceptable calibration of the precipitation-streamflow relationships, (ii) there is challenges in the identification of parameterizations based on only calibration to catchment integrated streamflow observations and (iii) a potential preference for the simple and parsimonious parameterizations for operational forecast contingent on their equivalent simulation performance for the available input data. In addition, the effects of non-identifiability of parameters (interactions and equifinality) can contribute to the non-identifiability of the parameterizations.

Comprehensive assessment of parameterization methods for estimating clear-sky surface downward longwave radiation

NASA Astrophysics Data System (ADS)

Guo, Yamin; Cheng, Jie; Liang, Shunlin

2018-02-01

Surface downward longwave radiation (SDLR) is a key variable for calculating the earth's surface radiation budget. In this study, we evaluated seven widely used clear-sky parameterization methods using ground measurements collected from 71 globally distributed fluxnet sites. The Bayesian model averaging (BMA) method was also introduced to obtain a multi-model ensemble estimate. As a whole, the parameterization method of Carmona et al. (2014) performs the best, with an average BIAS, RMSE, and R 2 of - 0.11 W/m2, 20.35 W/m2, and 0.92, respectively, followed by the parameterization methods of Idso (1981), Prata (Q J R Meteorol Soc 122:1127-1151, 1996), Brunt and Sc (Q J R Meteorol Soc 58:389-420, 1932), and Brutsaert (Water Resour Res 11:742-744, 1975). The accuracy of the BMA is close to that of the parameterization method of Carmona et al. (2014) and comparable to that of the parameterization method of Idso (1981). The advantage of the BMA is that it achieves balanced results compared to the integrated single parameterization methods. To fully assess the performance of the parameterization methods, the effects of climate type, land cover, and surface elevation were also investigated. The five parameterization methods and BMA all failed over land with the tropical climate type, with high water vapor, and had poor results over forest, wetland, and ice. These methods achieved better results over desert, bare land, cropland, and grass and had acceptable accuracies for sites at different elevations, except for the parameterization method of Carmona et al. (2014) over high elevation sites. Thus, a method that can be successfully applied everywhere does not exist.

Evaluation of wave runup predictions from numerical and parametric models

USGS Publications Warehouse

Stockdon, Hilary F.; Thompson, David M.; Plant, Nathaniel G.; Long, Joseph W.

2014-01-01

Wave runup during storms is a primary driver of coastal evolution, including shoreline and dune erosion and barrier island overwash. Runup and its components, setup and swash, can be predicted from a parameterized model that was developed by comparing runup observations to offshore wave height, wave period, and local beach slope. Because observations during extreme storms are often unavailable, a numerical model is used to simulate the storm-driven runup to compare to the parameterized model and then develop an approach to improve the accuracy of the parameterization. Numerically simulated and parameterized runup were compared to observations to evaluate model accuracies. The analysis demonstrated that setup was accurately predicted by both the parameterized model and numerical simulations. Infragravity swash heights were most accurately predicted by the parameterized model. The numerical model suffered from bias and gain errors that depended on whether a one-dimensional or two-dimensional spatial domain was used. Nonetheless, all of the predictions were significantly correlated to the observations, implying that the systematic errors can be corrected. The numerical simulations did not resolve the incident-band swash motions, as expected, and the parameterized model performed best at predicting incident-band swash heights. An assimilated prediction using a weighted average of the parameterized model and the numerical simulations resulted in a reduction in prediction error variance. Finally, the numerical simulations were extended to include storm conditions that have not been previously observed. These results indicated that the parameterized predictions of setup may need modification for extreme conditions; numerical simulations can be used to extend the validity of the parameterized predictions of infragravity swash; and numerical simulations systematically underpredict incident swash, which is relatively unimportant under extreme conditions.

Effects of Static and Dynamic Stretching on the Isokinetic Peak Torques and Electromyographic Activities of the Antagonist Muscles.

PubMed

Serefoglu, Abdullah; Sekir, Ufuk; Gür, Hakan; Akova, Bedrettin

2017-03-01

The aim of this study was to investigate if static and dynamic stretching exercises of the knee muscles (quadriceps and hamstring muscles) have any effects on concentric and eccentric isokinetic peak torques and electromyographic amplitudes (EMG) of the antagonist muscles. Twenty healthy male athletes (age between 18-30 years) voluntarily participated in this study. All of the subjects visited the laboratory to complete the following intervention in a randomized order on 5 separate days; (a) non-stretching (control), (b) static stretching of the quadriceps muscles, (c) static stretching of the hamstring muscles, (d) dynamic stretching of the quadriceps muscles, and (e) dynamic stretching of the hamstring muscles. Static stretching exercises either for the quadriceps or the hamstring muscles were carried out at the standing and sitting positions. Subjects performed four successive repetitions of each stretching exercises for 30 seconds in both stretching positions. Similar to static stretching exercises two different stretching modes were designed for dynamic stretching exercises. Concentric and eccentric isokinetic peak torque for the non-stretched antagonist quadriceps or hamstring muscles at angular velocities of 60°/sec and 240°/sec and their concurrent electromyographic (EMG) activities were measured before and immediately after the intervention. Isokinetic peak torques of the non-stretched agonist hamstring and quadriceps muscles did not represent any significant (p > 0.05) differences following static and dynamic stretching of the antagonist quadriceps and hamstring muscles, respectively. Similarly, the EMG activities of the agonist muscles exhibited no significant alterations (p > 0.05) following both stretching exercises of the antagonist muscles. According to the results of the present study it is possible to state that antagonist stretching exercises either in the static or dynamic modes do not affect the isokinetic peak torques and the EMG activities of the non-stretched agonist quadriceps or hamstring muscles.

Hamstring Stiffness Returns More Rapidly After Static Stretching Than Range of Motion, Stretch Tolerance, and Isometric Peak Torque.

PubMed

Hatano, Genki; Suzuki, Shigeyuki; Matsuo, Shingo; Kataura, Satoshi; Yokoi, Kazuaki; Fukaya, Taizan; Fujiwara, Mitsuhiro; Asai, Yuji; Iwata, Masahiro

2017-12-18

Hamstring injuries are common, and lack of hamstring flexibility may predispose to injury. Static stretching increases range of motion (ROM) but also results in reduced muscle strength after stretching. The effects of stretching on the hamstring muscles and the duration of these effects remain unclear. To determine the effects of static stretching on the hamstrings and the duration of these effects. Randomized crossover study. University laboratory. Twenty-four healthy volunteers. We measured the torque-angle relationship (ROM, passive torque (PT) at the onset of pain, and passive stiffness) and isometric muscle force using an isokinetic dynamometer. After a 60-minute rest, the ROM of the dynamometer was set at maximum tolerable intensity; this position was maintained for 300 seconds while static passive torque (SPT) was measured continuously. We remeasured the torque-angle relationship and isometric muscle force after rest periods of 10, 20, and 30 minutes. Change in SPT during stretching; changes in ROM, PT at the onset of pain, passive stiffness, and isometric muscle force before stretching compared with 10, 20, and 30 minutes after stretching. SPT decreased significantly during stretching. Passive stiffness decreased significantly 10 and 20 minutes after stretching, but there was no significant pre- vs. post-stretching difference after 30 minutes. PT at the onset of pain and ROM increased significantly after stretching at all rest intervals, while isometric muscle force decreased significantly after all rest intervals. The effect of static stretching on passive stiffness of the hamstrings was not maintained as long as the changes in ROM, stretch tolerance, and isometric muscle force. Therefore, frequent stretching is necessary to improve the viscoelasticity of the muscle-tendon unit. Muscle force was decreased for 30 minutes after stretching; this should be considered prior to activities requiring maximal muscle strength.

Stretch-induced contraction in pulmonary arteries.

PubMed

Kulik, T J; Evans, J N; Gamble, W J

1988-12-01

Stretch stimulates contraction of systemic blood vessels, but the response has not been described in pulmonary vessels. To determine whether pulmonary arteries contract when stretched, isolated cylindrical segments of pulmonary arteries were suspended between two parallel wires, stretched, and the active force was generated in response to stretch measured. Eighty-nine percent of segments from small (in situ diameter less than 1,000 microns) feline pulmonary arteries contracted when stretched, and in 65% of these the magnitude of stretch was related to the magnitude of contraction. Large (in situ diameter greater than or equal to 1,000 microns) feline pulmonary arteries did not contract with stretch. Multiple, rapidly repeated stretches resulted in a diminution of active force development. Stretch-induced contraction required external Ca2+ and was abolished by diltiazem (10 microns), but it was not affected by phenoxybenzamine, phentolamine, diethylcarbamazine, or mechanical removal of endothelium. Indomethacin blunted but did not abolish stretch-induced contraction, an effect that may have been nonspecific. This study suggests that stretch can act, probably directly, on smooth muscle in small feline pulmonary arteries to elicit contraction and that it may be a determinant of pulmonary vascular tone. In addition, feline pulmonary arteries are suitable for the in vitro study of stretch-induced contraction.

Correction of Excessive Precipitation over Steep and High Mountains in a GCM: A Simple Method of Parameterizing the Thermal Effects of Subgrid Topographic Variation

NASA Technical Reports Server (NTRS)

Chao, Winston C.

2015-01-01

The excessive precipitation over steep and high mountains (EPSM) in GCMs and meso-scale models is due to a lack of parameterization of the thermal effects of the subgrid-scale topographic variation. These thermal effects drive subgrid-scale heated slope induced vertical circulations (SHVC). SHVC provide a ventilation effect of removing heat from the boundary layer of resolvable-scale mountain slopes and depositing it higher up. The lack of SHVC parameterization is the cause of EPSM. The author has previously proposed a method of parameterizing SHVC, here termed SHVC.1. Although this has been successful in avoiding EPSM, the drawback of SHVC.1 is that it suppresses convective type precipitation in the regions where it is applied. In this article we propose a new method of parameterizing SHVC, here termed SHVC.2. In SHVC.2 the potential temperature and mixing ratio of the boundary layer are changed when used as input to the cumulus parameterization scheme over mountainous regions. This allows the cumulus parameterization to assume the additional function of SHVC parameterization. SHVC.2 has been tested in NASA Goddard's GEOS-5 GCM. It achieves the primary goal of avoiding EPSM while also avoiding the suppression of convective-type precipitation in regions where it is applied.

Cessation of cyclic stretch induces atrophy of C2C12 myotubes.

PubMed

Soltow, Quinlyn A; Zeanah, Elizabeth H; Lira, Vitor A; Criswell, David S

2013-05-03

Cyclic stretch of differentiated myotubes mimics the loading pattern of mature skeletal muscle. We tested a cell culture model of disuse atrophy by the cessation of repetitive bouts of cyclic stretch in differentiated C2C12 myotubes. Myotubes were subjected to cyclic strain (12%, 0.7 Hz, 1 h/d) on collagen-I-coated Bioflex plates using a computer-controlled vacuum stretch apparatus (Flexcell Int.) for 2 (2dSTR) or 5 (5dSTR) consecutive days. Control cultures were maintained in the Bioflex plates without cyclic stretch for 2d or 5d. Additionally, some cultures were stretched for 2 d followed by cessation of stretch for 3d (2dSTR3dCES). Cyclic stretching (5dSTR) increased myotube diameter and overall myotube area by ~2-fold (P<0.05) compared to non-stretched controls, while cessation of stretch (2dSTR3dCES) resulted in ~80% smaller myotubes than 5dSTR cells, and 40-50% smaller than non-stretched controls (P<0.05). Further, the calpain-dependent cleavage products of αII-spectrin (150 kDa) and talin increased (3.5-fold and 2.2-fold, respectively; P<0.05) in 2dSTR3dCES myotubes, compared to non-stretched controls. The 1h cyclic stretching protocol acutely increased the phosphorylation of Akt (+4.5-fold; P<0.05) and its downstream targets, FOXO3a (+4.2-fold; P<0.05) and GSK-3β (+1.8-fold; P<0.05), which returned to baseline by 48 h after cessation of stretch. Additionally, nitric oxide production increased during stretch and co-treatment with the NOS inhibitor, l-NAME, inhibited the effects of stretch and cessation of stretch. We conclude that cessation of cyclic stretching causes myotube atrophy by activating calpains and decreasing activation of Akt. Stretch-induced myotube growth, as well as activation of atrophy signaling with cessation of stretch, are dependent on NOS activity. Copyright © 2013 Elsevier Inc. All rights reserved.

Evaluation of scale-aware subgrid mesoscale eddy models in a global eddy-rich model

NASA Astrophysics Data System (ADS)

Pearson, Brodie; Fox-Kemper, Baylor; Bachman, Scott; Bryan, Frank

2017-07-01

Two parameterizations for horizontal mixing of momentum and tracers by subgrid mesoscale eddies are implemented in a high-resolution global ocean model. These parameterizations follow on the techniques of large eddy simulation (LES). The theory underlying one parameterization (2D Leith due to Leith, 1996) is that of enstrophy cascades in two-dimensional turbulence, while the other (QG Leith) is designed for potential enstrophy cascades in quasi-geostrophic turbulence. Simulations using each of these parameterizations are compared with a control simulation using standard biharmonic horizontal mixing.Simulations using the 2D Leith and QG Leith parameterizations are more realistic than those using biharmonic mixing. In particular, the 2D Leith and QG Leith simulations have more energy in resolved mesoscale eddies, have a spectral slope more consistent with turbulence theory (an inertial enstrophy or potential enstrophy cascade), have bottom drag and vertical viscosity as the primary sinks of energy instead of lateral friction, and have isoneutral parameterized mesoscale tracer transport. The parameterization choice also affects mass transports, but the impact varies regionally in magnitude and sign.

A randomized controlled trial for the effect of passive stretching on measures of hamstring extensibility, passive stiffness, strength, and stretch tolerance.

PubMed

Marshall, Paul W M; Cashman, Anthony; Cheema, Birinder S

2011-11-01

To measure hamstring extensibility, stiffness, stretch tolerance, and strength following a 4-week passive stretching program. Randomized controlled trial. Twenty-two healthy participants were randomly assigned to either a 4-week stretching program consisting of 4 hamstring and hip stretches performed 5 times per week, or a non-stretching control group. Hamstring extensibility and stiffness were measured before and after training using the instrumented straight leg raise test (iSLR). Stretch tolerance was measured as the pain intensity (visual analog scale; VAS) elicited during the maximal stretch. Hamstring strength was measured using isokinetic dynamometry at 30 and 120° s(-1). Hamstring extensibility increased by 20.9% in the intervention group following 4 weeks of training (p<0.001; d=0.86). Passive stiffness was reduced by 31% in the intervention group (p<0.05; d=-0.89). Stretch tolerance VAS scores were not different between groups at either time point, and no changes were observed following training. There were no changes in hamstring concentric strength measured at 30 and 120° s(-1). Passive stretching increases hamstring extensibility and decreases passive stiffness, with no change in stretch tolerance defined by pain intensity during the stretch. Compared to previous research, the volume of stretching was higher in this study. The volume of prescribed stretching is important for eliciting the strong clinical effect observed in this study. Copyright © 2011 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

Short Durations of Static Stretching when Combined with Dynamic Stretching do not Impair Repeated Sprints and Agility

PubMed Central

Wong, Del P.; Chaouachi, Anis; Lau, Patrick W.C.; Behm, David G.

2011-01-01

This study aimed to compare the effect of different static stretching durations followed by dynamic stretching on repeated sprint ability (RSA) and change of direction (COD). Twenty-five participants performed the RSA and COD tests in a randomized order. After a 5 min aerobic warm up, participants performed one of the three static stretching protocols of 30 s, 60 s or 90 s total duration (3 stretches x 10 s, 20 s or 30 s). Three dynamic stretching exercises of 30 s duration were then performed (90 s total). Sit-and-reach flexibility tests were conducted before the aerobic warm up, after the combined static and dynamic stretching, and post- RSA/COD test. The duration of static stretching had a positive effect on flexibility with 36.3% and 85.6% greater sit-and-reach scores with the 60 s and 90 s static stretching conditions respectively than with the 30 s condition (p ≤ 0.001). However there were no significant differences in RSA and COD performance between the 3 stretching conditions. The lack of change in RSA and COD might be attributed to a counterbalancing of static and dynamic stretching effects. Furthermore, the short duration (≤ 90 s) static stretching may not have provided sufficient stimulus to elicit performance impairments. Key points The duration of combined static and dynamic stretching had a positive effect on flexibility with 36.3% and 85.6% greater sit and reach scores with the 60 s and 90 s static stretching conditions respectively than with the 30 s condition (p ≤ 0.001). No significant differences in RSA and COD between the 3 stretching conditions. The lack of change in RSA and COD might be attributed to a counterbalancing of static and dynamic stretching effects. The short duration (≤ 90 s) static stretching may not have provided sufficient stimulus to elicit performance impairments. PMID:24149890

The effectiveness of manual stretching in the treatment of plantar heel pain: a systematic review

PubMed Central

2011-01-01

Background Plantar heel pain is a commonly occurring foot complaint. Stretching is frequently utilised as a treatment, yet a systematic review focusing only on its effectiveness has not been published. This review aimed to assess the effectiveness of stretching on pain and function in people with plantar heel pain. Methods Medline, EMBASE, CINAHL, AMED, and The Cochrane Library were searched from inception to July 2010. Studies fulfilling the inclusion criteria were independently assessed, and their quality evaluated using the modified PEDro scale. Results Six studies including 365 symptomatic participants were included. Two compared stretching with a control, one study compared stretching to an alternative intervention, one study compared stretching to both alternative and control interventions, and two compared different stretching techniques and durations. Quality rating on the modified Pedro scale varied from two to eight out of a maximum of ten points. The methodologies and interventions varied significantly between studies, making meta-analysis inappropriate. Most participants improved over the course of the studies, but when stretching was compared to alternative or control interventions, the changes only reached statistical significance in one study that used a combination of calf muscle stretches and plantar fascia stretches in their stretching programme. Another study comparing different stretching techniques, showed a statistically significant reduction in some aspects of pain in favour of plantar fascia stretching over calf stretches in the short term. Conclusions There were too few studies to assess whether stretching is effective compared to control or other interventions, for either pain or function. However, there is some evidence that plantar fascia stretching may be more effective than Achilles tendon stretching alone in the short-term. Appropriately powered randomised controlled trials, utilizing validated outcome measures, blinded assessors and long-term follow up are needed to assess the efficacy of stretching. PMID:21703003

Short Durations of Static Stretching when Combined with Dynamic Stretching do not Impair Repeated Sprints and Agility.

PubMed

Wong, Del P; Chaouachi, Anis; Lau, Patrick W C; Behm, David G

2011-01-01

This study aimed to compare the effect of different static stretching durations followed by dynamic stretching on repeated sprint ability (RSA) and change of direction (COD). Twenty-five participants performed the RSA and COD tests in a randomized order. After a 5 min aerobic warm up, participants performed one of the three static stretching protocols of 30 s, 60 s or 90 s total duration (3 stretches x 10 s, 20 s or 30 s). Three dynamic stretching exercises of 30 s duration were then performed (90 s total). Sit-and-reach flexibility tests were conducted before the aerobic warm up, after the combined static and dynamic stretching, and post- RSA/COD test. The duration of static stretching had a positive effect on flexibility with 36.3% and 85.6% greater sit-and-reach scores with the 60 s and 90 s static stretching conditions respectively than with the 30 s condition (p ≤ 0.001). However there were no significant differences in RSA and COD performance between the 3 stretching conditions. The lack of change in RSA and COD might be attributed to a counterbalancing of static and dynamic stretching effects. Furthermore, the short duration (≤ 90 s) static stretching may not have provided sufficient stimulus to elicit performance impairments. Key pointsThe duration of combined static and dynamic stretching had a positive effect on flexibility with 36.3% and 85.6% greater sit and reach scores with the 60 s and 90 s static stretching conditions respectively than with the 30 s condition (p ≤ 0.001).No significant differences in RSA and COD between the 3 stretching conditions.The lack of change in RSA and COD might be attributed to a counterbalancing of static and dynamic stretching effects.The short duration (≤ 90 s) static stretching may not have provided sufficient stimulus to elicit performance impairments.

A randomized controlled comparison of stretching procedures for posterior shoulder tightness.

PubMed

McClure, Philip; Balaicuis, Jenna; Heiland, David; Broersma, Mary Ellen; Thorndike, Cheryl K; Wood, April

2007-03-01

Randomized controlled trial, To compare changes in shoulder internal rotation range of motion (ROM), for 2 stretching exercises, the "cross-body stretch" and the "sleeper stretch," in individuals with posterior shoulder tightness. Recently, some authors have expressed the belief that the sleeper stretch is better than the cross-body stretch to address glenohumeral posterior tightness because the scapula is stabilized. Fifty-four asymptomatic subjects (20 males, 34 females) participated in the study. The control group (n=24) consisted of subjects with a between-shoulder difference in internal rotation ROM of less than 10 degrees, whereas those subjects with more than a 10 degrees difference were randomly assigned to 1 of 2 intervention groups, the sleeper stretch group (n=15) or the cross-body stretch group (n=15). Shoulder internal rotation ROM, with the arm abducted to 90 degrees and scapula motion prevented, was measured before and after a 4-week intervention period. Subjects in the control group were asked not to engage in any new stretching activities, while subjects in the 2 stretching groups were asked to perform stretching exercises on the more limited side only, once daily for 5 repetitions, holding each stretch for 30 seconds. The improvements in internal rotation ROM for the subjects in the cross-body stretch group (mean +/- SD, 20.0 degrees +/- 12.9 degrees) were significantly greater than for the subjects in the control group (5.9 degrees +/- 9.4 degrees, P = .009). The gains in the sleeper stretch group (12.4 degrees +/- 10.4 degrees) were not significant compared to those of the control group (P = .586) and those of the cross-body stretch group (P = .148). The cross-body stretch in individuals with limited shoulder internal rotation ROM appears to be more effective than no stretching in controls without internal rotation asymmetry to improve shoulder internal rotation ROM. While the improvement in internal rotation from the cross-body stretch was greater than for the sleeper stretch and of a magnitude that could be clinically significant, the small sample size likely precluded statistical significance between groups.

Effect of acute stretch injury on action potential and network activity of rat neocortical neurons in culture.

PubMed

Magou, George C; Pfister, Bryan J; Berlin, Joshua R

2015-10-22

The basis for acute seizures following traumatic brain injury (TBI) remains unclear. Animal models of TBI have revealed acute hyperexcitablility in cortical neurons that could underlie seizure activity, but studying initiating events causing hyperexcitability is difficult in these models. In vitro models of stretch injury with cultured cortical neurons, a surrogate for TBI, allow facile investigation of cellular changes after injury but they have only demonstrated post-injury hypoexcitability. The goal of this study was to determine if neuronal hyperexcitability could be triggered by in vitro stretch injury. Controlled uniaxial stretch injury was delivered to a spatially delimited region of a spontaneously active network of cultured rat cortical neurons, yielding a region of stretch-injured neurons and adjacent regions of non-stretched neurons that did not directly experience stretch injury. Spontaneous electrical activity was measured in non-stretched and stretch-injured neurons, and in control neuronal networks not subjected to stretch injury. Non-stretched neurons in stretch-injured cultures displayed a three-fold increase in action potential firing rate and bursting activity 30-60 min post-injury. Stretch-injured neurons, however, displayed dramatically lower rates of action potential firing and bursting. These results demonstrate that acute hyperexcitability can be observed in non-stretched neurons located in regions adjacent to the site of stretch injury, consistent with reports that seizure activity can arise from regions surrounding the site of localized brain injury. Thus, this in vitro procedure for localized neuronal stretch injury may provide a model to study the earliest cellular changes in neuronal function associated with acute post-traumatic seizures. Copyright © 2015. Published by Elsevier B.V.

Ca{sup 2+} influx and ATP release mediated by mechanical stretch in human lung fibroblasts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Murata, Naohiko; Ito, Satoru, E-mail: itori@med.nagoya-u.ac.jp; Furuya, Kishio

Highlights: • Uniaxial stretching activates Ca{sup 2+} signaling in human lung fibroblasts. • Stretch-induced intracellular Ca{sup 2+} elevation is mainly via Ca{sup 2+} influx. • Mechanical strain enhances ATP release from fibroblasts. • Stretch-induced Ca{sup 2+} influx is not mediated by released ATP or actin cytoskeleton. - Abstract: One cause of progressive pulmonary fibrosis is dysregulated wound healing after lung inflammation or damage in patients with idiopathic pulmonary fibrosis and severe acute respiratory distress syndrome. The mechanical forces are considered to regulate pulmonary fibrosis via activation of lung fibroblasts. In this study, the effects of mechanical stretch on the intracellularmore » Ca{sup 2+} concentration ([Ca{sup 2+}]{sub i}) and ATP release were investigated in primary human lung fibroblasts. Uniaxial stretch (10–30% in strain) was applied to fibroblasts cultured in a silicone chamber coated with type I collagen using a stretching apparatus. Following stretching and subsequent unloading, [Ca{sup 2+}]{sub i} transiently increased in a strain-dependent manner. Hypotonic stress, which causes plasma membrane stretching, also transiently increased the [Ca{sup 2+}]{sub i}. The stretch-induced [Ca{sup 2+}]{sub i} elevation was attenuated in Ca{sup 2+}-free solution. In contrast, the increase of [Ca{sup 2+}]{sub i} by a 20% stretch was not inhibited by the inhibitor of stretch-activated channels GsMTx-4, Gd{sup 3+}, ruthenium red, or cytochalasin D. Cyclic stretching induced significant ATP releases from fibroblasts. However, the stretch-induced [Ca{sup 2+}]{sub i} elevation was not inhibited by ATP diphosphohydrolase apyrase or a purinergic receptor antagonist suramin. Taken together, mechanical stretch induces Ca{sup 2+} influx independently of conventional stretch-sensitive ion channels, the actin cytoskeleton, and released ATP.« less

Prophylactic stretching does not reduce cramp susceptibility.

PubMed

Miller, Kevin C; Harsen, James D; Long, Blaine C

2018-03-01

Some clinicians advocate stretching to prevent muscle cramps. It is unknown whether static or proprioceptive neuromuscular facilitation (PNF) stretching increases cramp threshold frequency (TF c ), a quantitative measure of cramp susceptibility. Fifteen individuals completed this randomized, counterbalanced, cross-over study. We measured passive hallux range of motion (ROM) and then performed 3 minutes of either static stretching, PNF stretching (hold-relax-with agonist contraction), or no stretching. ROM was reassessed and TF c was measured. PNF stretching increased hallux extension (pre-PNF 81 ± 11°, post-PNF 90 ± 10°; P < 0.05) but not hallux flexion (pre-PNF 40 ± 7°, post-PNF 40 ± 7°; P > 0.05). Static stretching increased hallux extension (pre-static 80 ± 11°, post-static 88 ± 9°; P < 0.05) but not hallux flexion (pre-static 38 ± 9°, post-static 39 ± 8°; P > 0.05). No ROM changes occurred with no stretching (P > 0.05). TF c was unaffected by stretching (no stretching 18 ± 7 Hz, PNF 16 ± 4 Hz, static 16 ± 5 Hz; P = 0.37). Static and PNF stretching increased hallux extension, but neither increased TF c . Acute stretching may not prevent muscle cramping. Muscle Nerve 57: 473-477, 2018. © 2017 Wiley Periodicals, Inc.

Evaluation of Surface Flux Parameterizations with Long-Term ARM Observations

DOE PAGES

Liu, Gang; Liu, Yangang; Endo, Satoshi

2013-02-01

Surface momentum, sensible heat, and latent heat fluxes are critical for atmospheric processes such as clouds and precipitation, and are parameterized in a variety of models ranging from cloud-resolving models to large-scale weather and climate models. However, direct evaluation of the parameterization schemes for these surface fluxes is rare due to limited observations. This study takes advantage of the long-term observations of surface fluxes collected at the Southern Great Plains site by the Department of Energy Atmospheric Radiation Measurement program to evaluate the six surface flux parameterization schemes commonly used in the Weather Research and Forecasting (WRF) model and threemore » U.S. general circulation models (GCMs). The unprecedented 7-yr-long measurements by the eddy correlation (EC) and energy balance Bowen ratio (EBBR) methods permit statistical evaluation of all six parameterizations under a variety of stability conditions, diurnal cycles, and seasonal variations. The statistical analyses show that the momentum flux parameterization agrees best with the EC observations, followed by latent heat flux, sensible heat flux, and evaporation ratio/Bowen ratio. The overall performance of the parameterizations depends on atmospheric stability, being best under neutral stratification and deteriorating toward both more stable and more unstable conditions. Further diagnostic analysis reveals that in addition to the parameterization schemes themselves, the discrepancies between observed and parameterized sensible and latent heat fluxes may stem from inadequate use of input variables such as surface temperature, moisture availability, and roughness length. The results demonstrate the need for improving the land surface models and measurements of surface properties, which would permit the evaluation of full land surface models.« less

Towards improved parameterization of a macroscale hydrologic model in a discontinuous permafrost boreal forest ecosystem

DOE PAGES

Endalamaw, Abraham; Bolton, W. Robert; Young-Robertson, Jessica M.; ...

2017-09-14

Modeling hydrological processes in the Alaskan sub-arctic is challenging because of the extreme spatial heterogeneity in soil properties and vegetation communities. Nevertheless, modeling and predicting hydrological processes is critical in this region due to its vulnerability to the effects of climate change. Coarse-spatial-resolution datasets used in land surface modeling pose a new challenge in simulating the spatially distributed and basin-integrated processes since these datasets do not adequately represent the small-scale hydrological, thermal, and ecological heterogeneity. The goal of this study is to improve the prediction capacity of mesoscale to large-scale hydrological models by introducing a small-scale parameterization scheme, which bettermore » represents the spatial heterogeneity of soil properties and vegetation cover in the Alaskan sub-arctic. The small-scale parameterization schemes are derived from observations and a sub-grid parameterization method in the two contrasting sub-basins of the Caribou Poker Creek Research Watershed (CPCRW) in Interior Alaska: one nearly permafrost-free (LowP) sub-basin and one permafrost-dominated (HighP) sub-basin. The sub-grid parameterization method used in the small-scale parameterization scheme is derived from the watershed topography. We found that observed soil thermal and hydraulic properties – including the distribution of permafrost and vegetation cover heterogeneity – are better represented in the sub-grid parameterization method than the coarse-resolution datasets. Parameters derived from the coarse-resolution datasets and from the sub-grid parameterization method are implemented into the variable infiltration capacity (VIC) mesoscale hydrological model to simulate runoff, evapotranspiration (ET), and soil moisture in the two sub-basins of the CPCRW. Simulated hydrographs based on the small-scale parameterization capture most of the peak and low flows, with similar accuracy in both sub-basins, compared to simulated hydrographs based on the coarse-resolution datasets. On average, the small-scale parameterization scheme improves the total runoff simulation by up to 50 % in the LowP sub-basin and by up to 10 % in the HighP sub-basin from the large-scale parameterization. This study shows that the proposed sub-grid parameterization method can be used to improve the performance of mesoscale hydrological models in the Alaskan sub-arctic watersheds.« less

Towards improved parameterization of a macroscale hydrologic model in a discontinuous permafrost boreal forest ecosystem

DOE Office of Scientific and Technical Information (OSTI.GOV)

Endalamaw, Abraham; Bolton, W. Robert; Young-Robertson, Jessica M.

Modeling hydrological processes in the Alaskan sub-arctic is challenging because of the extreme spatial heterogeneity in soil properties and vegetation communities. Nevertheless, modeling and predicting hydrological processes is critical in this region due to its vulnerability to the effects of climate change. Coarse-spatial-resolution datasets used in land surface modeling pose a new challenge in simulating the spatially distributed and basin-integrated processes since these datasets do not adequately represent the small-scale hydrological, thermal, and ecological heterogeneity. The goal of this study is to improve the prediction capacity of mesoscale to large-scale hydrological models by introducing a small-scale parameterization scheme, which bettermore » represents the spatial heterogeneity of soil properties and vegetation cover in the Alaskan sub-arctic. The small-scale parameterization schemes are derived from observations and a sub-grid parameterization method in the two contrasting sub-basins of the Caribou Poker Creek Research Watershed (CPCRW) in Interior Alaska: one nearly permafrost-free (LowP) sub-basin and one permafrost-dominated (HighP) sub-basin. The sub-grid parameterization method used in the small-scale parameterization scheme is derived from the watershed topography. We found that observed soil thermal and hydraulic properties – including the distribution of permafrost and vegetation cover heterogeneity – are better represented in the sub-grid parameterization method than the coarse-resolution datasets. Parameters derived from the coarse-resolution datasets and from the sub-grid parameterization method are implemented into the variable infiltration capacity (VIC) mesoscale hydrological model to simulate runoff, evapotranspiration (ET), and soil moisture in the two sub-basins of the CPCRW. Simulated hydrographs based on the small-scale parameterization capture most of the peak and low flows, with similar accuracy in both sub-basins, compared to simulated hydrographs based on the coarse-resolution datasets. On average, the small-scale parameterization scheme improves the total runoff simulation by up to 50 % in the LowP sub-basin and by up to 10 % in the HighP sub-basin from the large-scale parameterization. This study shows that the proposed sub-grid parameterization method can be used to improve the performance of mesoscale hydrological models in the Alaskan sub-arctic watersheds.« less

The effects of a combined static-dynamic stretching protocol on athletic performance in elite Gaelic footballers: A randomised controlled crossover trial.

PubMed

Loughran, Martin; Glasgow, Philip; Bleakley, Chris; McVeigh, Joseph

2017-05-01

To determine the effect of three different static-dynamic stretching protocols on sprint and jump performance in Gaelic footballers. Double-blind, controlled, crossover trial. Sports Institute research environment. Seventeen male elite level Gaelic footballers, aged 18-30 years, completed three stretching protocols. Athletic performance was measured by countermovement jump height and power, and timed 10 m, 20 m, and 40 m sprints. Static stretching reduced sprint speed by 1.1% over 40 m and 1.0% over 20 m. Static stretching also reduced countermovement jump height by 10.6% and jump power by 6.4%. When static stretching was followed by dynamic stretching, sprint speed improved by 1.0% over 20 m and 0.7% over 40 m (p < 0.05). The static - dynamic stretching protocol also improved countermovement jump height by 8.7% (p < 0.01) and power by 6.7% (p < 0.01). Static stretching reduces sprint speed and jump performance. Static stretching should be followed by dynamic stretching during warm-up to nullify any performance deficits caused by static stretching. Copyright © 2016 Elsevier Ltd. All rights reserved.

Mechanical stretching for tissue engineering: two-dimensional and three-dimensional constructs.

PubMed

Riehl, Brandon D; Park, Jae-Hong; Kwon, Il Keun; Lim, Jung Yul

2012-08-01

Mechanical cell stretching may be an attractive strategy for the tissue engineering of mechanically functional tissues. It has been demonstrated that cell growth and differentiation can be guided by cell stretch with minimal help from soluble factors and engineered tissues that are mechanically stretched in bioreactors may have superior organization, functionality, and strength compared with unstretched counterparts. This review explores recent studies on cell stretching in both two-dimensional (2D) and three-dimensional (3D) setups focusing on the applications of stretch stimulation as a tool for controlling cell orientation, growth, gene expression, lineage commitment, and differentiation and for achieving successful tissue engineering of mechanically functional tissues, including cardiac, muscle, vasculature, ligament, tendon, bone, and so on. Custom stretching devices and lab-specific mechanical bioreactors are described with a discussion on capabilities and limitations. While stretch mechanotransduction pathways have been examined using 2D stretch, studying such pathways in physiologically relevant 3D environments may be required to understand how cells direct tissue development under stretch. Cell stretch study using 3D milieus may also help to develop tissue-specific stretch regimens optimized with biochemical feedback, which once developed will provide optimal tissue engineering protocols.

Mechanical Stretching for Tissue Engineering: Two-Dimensional and Three-Dimensional Constructs

PubMed Central

Riehl, Brandon D.; Park, Jae-Hong; Kwon, Il Keun

2012-01-01

Mechanical cell stretching may be an attractive strategy for the tissue engineering of mechanically functional tissues. It has been demonstrated that cell growth and differentiation can be guided by cell stretch with minimal help from soluble factors and engineered tissues that are mechanically stretched in bioreactors may have superior organization, functionality, and strength compared with unstretched counterparts. This review explores recent studies on cell stretching in both two-dimensional (2D) and three-dimensional (3D) setups focusing on the applications of stretch stimulation as a tool for controlling cell orientation, growth, gene expression, lineage commitment, and differentiation and for achieving successful tissue engineering of mechanically functional tissues, including cardiac, muscle, vasculature, ligament, tendon, bone, and so on. Custom stretching devices and lab-specific mechanical bioreactors are described with a discussion on capabilities and limitations. While stretch mechanotransduction pathways have been examined using 2D stretch, studying such pathways in physiologically relevant 3D environments may be required to understand how cells direct tissue development under stretch. Cell stretch study using 3D milieus may also help to develop tissue-specific stretch regimens optimized with biochemical feedback, which once developed will provide optimal tissue engineering protocols. PMID:22335794

Activation Dependence of Stretch Activation in Mouse Skinned Myocardium: Implications for Ventricular Function

PubMed Central

Stelzer, Julian E.; Larsson, Lars; Fitzsimons, Daniel P.; Moss, Richard L.

2006-01-01

Recent evidence suggests that ventricular ejection is partly powered by a delayed development of force, i.e., stretch activation, in regions of the ventricular wall due to stretch resulting from torsional twist of the ventricle around the apex-to-base axis. Given the potential importance of stretch activation in cardiac function, we characterized the stretch activation response and its Ca2+ dependence in murine skinned myocardium at 22°C in solutions of varying Ca2+ concentrations. Stretch activation was induced by suddenly imposing a stretch of 0.5–2.5% of initial length to the isometrically contracting muscle and then holding the muscle at the new length. The force response to stretch was multiphasic: force initially increased in proportion to the amount of stretch, reached a peak, and then declined to a minimum before redeveloping to a new steady level. This last phase of the response is the delayed force characteristic of myocardial stretch activation and is presumably due to increased attachment of cross-bridges as a consequence of stretch. The amplitude and rate of stretch activation varied with Ca2+ concentration and more specifically with the level of isometric force prior to the stretch. Since myocardial force is regulated both by Ca2+ binding to troponin-C and cross-bridge binding to thin filaments, we explored the role of cross-bridge binding in the stretch activation response using NEM-S1, a strong-binding, non-force–generating derivative of myosin subfragment 1. NEM-S1 treatment at submaximal Ca2+-activated isometric forces significantly accelerated the rate of the stretch activation response and reduced its amplitude. These data show that the rate and amplitude of myocardial stretch activation vary with the level of activation and that stretch activation involves cooperative binding of cross-bridges to the thin filament. Such a mechanism would contribute to increased systolic ejection in response to increased delivery of activator Ca2+ during excitation–contraction coupling. PMID:16446502

Extensions and applications of a second-order landsurface parameterization

NASA Technical Reports Server (NTRS)

Andreou, S. A.; Eagleson, P. S.

1983-01-01

Extensions and applications of a second order land surface parameterization, proposed by Andreou and Eagleson are developed. Procedures for evaluating the near surface storage depth used in one cell land surface parameterizations are suggested and tested by using the model. Sensitivity analysis to the key soil parameters is performed. A case study involving comparison with an "exact" numerical model and another simplified parameterization, under very dry climatic conditions and for two different soil types, is also incorporated.

Development and Testing of Coupled Land-surface, PBL and Shallow/Deep Convective Parameterizations within the MM5

NASA Technical Reports Server (NTRS)

Stauffer, David R.; Seaman, Nelson L.; Munoz, Ricardo C.

2000-01-01

The objective of this investigation was to study the role of shallow convection on the regional water cycle of the Mississippi and Little Washita Basins using a 3-D mesoscale model, the PSUINCAR MM5. The underlying premise of the project was that current modeling of regional-scale climate and moisture cycles over the continents is deficient without adequate treatment of shallow convection. It was hypothesized that an improved treatment of the regional water cycle can be achieved by using a 3-D mesoscale numerical model having a detailed land-surface parameterization, an advanced boundary-layer parameterization, and a more complete shallow convection parameterization than are available in most current models. The methodology was based on the application in the MM5 of new or recently improved parameterizations covering these three physical processes. Therefore, the work plan focused on integrating, improving, and testing these parameterizations in the MM5 and applying them to study water-cycle processes over the Southern Great Plains (SGP): (1) the Parameterization for Land-Atmosphere-Cloud Exchange (PLACE) described by Wetzel and Boone; (2) the 1.5-order turbulent kinetic energy (TKE)-predicting scheme of Shafran et al.; and (3) the hybrid-closure sub-grid shallow convection parameterization of Deng. Each of these schemes has been tested extensively through this study and the latter two have been improved significantly to extend their capabilities.

PNF and Other Flexibility Techniques.

ERIC Educational Resources Information Center

Cornelius, William L.

Effective flexibility procedures are one of the essential tools by which excellence can be attained. Although stretching exercises provide obvious benefits, negative outcomes can result unless effective stretching procedures are incoroporated. Characteristics of effective stretching include warmup before stretching, stretch before and after…

A Simple Parameterization of 3 x 3 Magic Squares

ERIC Educational Resources Information Center

Trenkler, Gotz; Schmidt, Karsten; Trenkler, Dietrich

2012-01-01

In this article a new parameterization of magic squares of order three is presented. This parameterization permits an easy computation of their inverses, eigenvalues, eigenvectors and adjoints. Some attention is paid to the Luoshu, one of the oldest magic squares.

Immediate Effects of Proprioceptive Neuromuscular Facilitation Stretching Programs Compared With Passive Stretching Programs for Hamstring Flexibility: A Critically Appraised Topic.

PubMed

Hill, Kristian J; Robinson, Kendall P; Cuchna, Jennifer W; Hoch, Matthew C

2017-11-01

Clinical Scenario: Increasing hamstring flexibility through clinical stretching interventions may be an effective means to prevent hamstring injuries. However the most effective method to increase hamstring flexibility has yet to be determined. For a healthy individual, are proprioceptive neuromuscular facilitation (PNF) stretching programs more effective in immediately improving hamstring flexibility when compared with static stretching programs? Summary of Key Findings: A thorough literature search returned 195 possible studies; 5 studies met the inclusion criteria and were included. Current evidence supports the use of PNF stretching or static stretching programs for increasing hamstring flexibility. However, neither program demonstrated superior effectiveness when examining immediate increases in hamstring flexibility. Clinical Bottom Line: There were consistent findings from multiple low-quality studies that indicate there is no difference in the immediate improvements in hamstring flexibility when comparing PNF stretching programs to static stretching programs in physically active adults. Strength of Recommendation: Grade B evidence exists that PNF and static stretching programs equally increase hamstring flexibility immediately following the stretching program.

Dynamically Consistent Parameterization of Mesoscale Eddies This work aims at parameterization of eddy effects for use in non-eddy-resolving ocean models and focuses on the effect of the stochastic part of the eddy forcing that backscatters and induces eastward jet extension of the western boundary currents and its adjacent recirculation zones.

NASA Astrophysics Data System (ADS)

Berloff, P. S.

2016-12-01

This work aims at developing a framework for dynamically consistent parameterization of mesoscale eddy effects for use in non-eddy-resolving ocean circulation models. The proposed eddy parameterization framework is successfully tested on the classical, wind-driven double-gyre model, which is solved both with explicitly resolved vigorous eddy field and in the non-eddy-resolving configuration with the eddy parameterization replacing the eddy effects. The parameterization focuses on the effect of the stochastic part of the eddy forcing that backscatters and induces eastward jet extension of the western boundary currents and its adjacent recirculation zones. The parameterization locally approximates transient eddy flux divergence by spatially localized and temporally periodic forcing, referred to as the plunger, and focuses on the linear-dynamics flow solution induced by it. The nonlinear self-interaction of this solution, referred to as the footprint, characterizes and quantifies the induced eddy forcing exerted on the large-scale flow. We find that spatial pattern and amplitude of each footprint strongly depend on the underlying large-scale flow, and the corresponding relationships provide the basis for the eddy parameterization and its closure on the large-scale flow properties. Dependencies of the footprints on other important parameters of the problem are also systematically analyzed. The parameterization utilizes the local large-scale flow information, constructs and scales the corresponding footprints, and then sums them up over the gyres to produce the resulting eddy forcing field, which is interactively added to the model as an extra forcing. Thus, the assumed ensemble of plunger solutions can be viewed as a simple model for the cumulative effect of the stochastic eddy forcing. The parameterization framework is implemented in the simplest way, but it provides a systematic strategy for improving the implementation algorithm.

Development of a two-dimensional zonally averaged statistical-dynamical model. III - The parameterization of the eddy fluxes of heat and moisture

NASA Technical Reports Server (NTRS)

Stone, Peter H.; Yao, Mao-Sung

1990-01-01

A number of perpetual January simulations are carried out with a two-dimensional zonally averaged model employing various parameterizations of the eddy fluxes of heat (potential temperature) and moisture. The parameterizations are evaluated by comparing these results with the eddy fluxes calculated in a parallel simulation using a three-dimensional general circulation model with zonally symmetric forcing. The three-dimensional model's performance in turn is evaluated by comparing its results using realistic (nonsymmetric) boundary conditions with observations. Branscome's parameterization of the meridional eddy flux of heat and Leovy's parameterization of the meridional eddy flux of moisture simulate the seasonal and latitudinal variations of these fluxes reasonably well, while somewhat underestimating their magnitudes. New parameterizations of the vertical eddy fluxes are developed that take into account the enhancement of the eddy mixing slope in a growing baroclinic wave due to condensation, and also the effect of eddy fluctuations in relative humidity. The new parameterizations, when tested in the two-dimensional model, simulate the seasonal, latitudinal, and vertical variations of the vertical eddy fluxes quite well, when compared with the three-dimensional model, and only underestimate the magnitude of the fluxes by 10 to 20 percent.

Dynamic "Range of Motion" Hindlimb Stretching Disrupts Locomotor Function in Rats with Moderate Subacute Spinal Cord Injuries.

PubMed

Keller, Anastasia; Rees, Kathlene; Prince, Daniella; Morehouse, Johnny; Shum-Siu, Alice; Magnuson, David

2017-06-15

Joint contractures and spasticity are two common secondary complications of a severe spinal cord injury (SCI), which can significantly reduce quality of life, and stretching is one of the top strategies for rehabilitation of these complications. We have previously shown that a daily static stretching protocol administered to rats at either acute or chronic time points after a moderate or moderate-severe T10 SCI significantly disrupts their hindlimb locomotor function. The objective of the current study was to examine the effects of dynamic range of motion (ROM) stretching on the locomotor function of rats with SCI as an alternative to static stretching. Starting at 6 weeks post-injury (T10 moderate contusion) eight adult Sprague-Dawley rats were subjected to hindlimb stretching for 4 weeks. Our standard stretching protocol (six maneuvers to stretch the major hindlimb muscle groups) was modified from 1 min static stretch-and-hold at the end ROM of each stretch position to a dynamic 2 sec hold, 1 sec release rhythm repeated for a duration of 1 min. Four weeks of daily (5 days/week) dynamic stretching led to significant disruption of locomotor function as assessed by the Basso, Beattie, Bresnahan (BBB) Open Field Locomotor Scale and three-dimensional (3D) kinematic and gait analyses. In addition, we identified and analyzed an apparently novel hindlimb response to dynamic stretch that resembles human clonus. The results of the current study extend the observation of the stretching phenomenon to a new modality of stretching that is also commonly used in SCI rehabilitation. Although mechanisms and clinical relevance still need to be established, our findings continue to raise concerns that stretching as a therapy can potentially hinder aspects of locomotor recovery.

Dynamic “Range of Motion” Hindlimb Stretching Disrupts Locomotor Function in Rats with Moderate Subacute Spinal Cord Injuries

PubMed Central

Keller, Anastasia; Rees, Kathlene; Prince, Daniella; Morehouse, Johnny; Shum-Siu, Alice

2017-01-01

Abstract Joint contractures and spasticity are two common secondary complications of a severe spinal cord injury (SCI), which can significantly reduce quality of life, and stretching is one of the top strategies for rehabilitation of these complications. We have previously shown that a daily static stretching protocol administered to rats at either acute or chronic time points after a moderate or moderate-severe T10 SCI significantly disrupts their hindlimb locomotor function. The objective of the current study was to examine the effects of dynamic range of motion (ROM) stretching on the locomotor function of rats with SCI as an alternative to static stretching. Starting at 6 weeks post-injury (T10 moderate contusion) eight adult Sprague–Dawley rats were subjected to hindlimb stretching for 4 weeks. Our standard stretching protocol (six maneuvers to stretch the major hindlimb muscle groups) was modified from 1 min static stretch-and-hold at the end ROM of each stretch position to a dynamic 2 sec hold, 1 sec release rhythm repeated for a duration of 1 min. Four weeks of daily (5 days/week) dynamic stretching led to significant disruption of locomotor function as assessed by the Basso, Beattie, Bresnahan (BBB) Open Field Locomotor Scale and three-dimensional (3D) kinematic and gait analyses. In addition, we identified and analyzed an apparently novel hindlimb response to dynamic stretch that resembles human clonus. The results of the current study extend the observation of the stretching phenomenon to a new modality of stretching that is also commonly used in SCI rehabilitation. Although mechanisms and clinical relevance still need to be established, our findings continue to raise concerns that stretching as a therapy can potentially hinder aspects of locomotor recovery. PMID:28288544

Cyclic stretch-induced stress fiber dynamics - Dependence on strain rate, Rho-kinase and MLCK

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Chin-Fu; Haase, Candice; Deguchi, Shinji

2010-10-22

Research highlights: {yields} Cyclic stretch induces stress fiber disassembly, reassembly and fusion perpendicular to the direction of stretch. {yields} Stress fiber disassembly and reorientation were not induced at low stretch frequency. {yields} Stretch caused actin fiber formation parallel to stretch in distinct locations in cells treated with Rho-kinase and MLCK inhibitors. -- Abstract: Stress fiber realignment is an important adaptive response to cyclic stretch for nonmuscle cells, but the mechanism by which such reorganization occurs is not known. By analyzing stress fiber dynamics using live cell microscopy, we revealed that stress fiber reorientation perpendicular to the direction of cyclic uniaxialmore » stretching at 1 Hz did not involve disassembly of the stress fiber distal ends located at focal adhesion sites. Instead, these distal ends were often used to assemble new stress fibers oriented progressively further away from the direction of stretch. Stress fiber disassembly and reorientation were not induced when the frequency of stretch was decreased to 0.01 Hz, however. Treatment with the Rho-kinase inhibitor (Y27632) reduced stress fibers to thin fibers located in the cell periphery which bundled together to form thick fibers oriented parallel to the direction of stretching at 1 Hz. In contrast, these thin fibers remained diffuse in cells subjected to stretch at 0.01 Hz. Cyclic stretch at 1 Hz also induced actin fiber formation parallel to the direction of stretch in cells treated with the myosin light chain kinase (MLCK) inhibitor ML-7, but these fibers were located centrally rather than peripherally. These results shed new light on the mechanism by which stress fibers reorient in response to cyclic stretch in different regions of the actin cytoskeleton.« less

Transient UV pump-IR probe investigation of heterocyclic ring-opening dynamics in the solution phase: the role played by nσ* states in the photoinduced reactions of thiophenone and furanone.

PubMed

Murdock, Daniel; Harris, Stephanie J; Luke, Joel; Grubb, Michael P; Orr-Ewing, Andrew J; Ashfold, Michael N R

2014-10-21

The heterocyclic ring-opening dynamics of thiophenone and furanone dissolved in CH3CN have been probed by ultrafast transient infrared spectroscopy. Following irradiation at 267 nm (thiophenone) or 225 nm (furanone), prompt (τ < 1 ps) ring-opening is confirmed by the appearance of a characteristic antisymmetric ketene stretching feature around 2150 cm(-1). The ring-opened product molecules are formed highly vibrationally excited, and cool subsequently on a ∼6.7 ps timescale. By monitoring the recovery of the parent (S0) bleach, it is found that ∼60% of the initially photoexcited thiophenone molecules reform the parent molecule, in stark contrast with the case in furanone where there is less than 10% parent bleach recovery. Complementary ab initio calculations of potential energy cuts along the S-C([double bond, length as m-dash]O) and O-C([double bond, length as m-dash]O) ring-opening coordinate reveals insights into the reaction mechanism, and the important role played by dissociative (n/π)σ* states in the UV-induced photochemistry of such heterocyclic systems.

Type IV pili mechanochemically regulate virulence factors in Pseudomonas aeruginosa.

PubMed

Persat, Alexandre; Inclan, Yuki F; Engel, Joanne N; Stone, Howard A; Gitai, Zemer

2015-06-16

Bacteria have evolved a wide range of sensing systems to appropriately respond to environmental signals. Here we demonstrate that the opportunistic pathogen Pseudomonas aeruginosa detects contact with surfaces on short timescales using the mechanical activity of its type IV pili, a major surface adhesin. This signal transduction mechanism requires attachment of type IV pili to a solid surface, followed by pilus retraction and signal transduction through the Chp chemosensory system, a chemotaxis-like sensory system that regulates cAMP production and transcription of hundreds of genes, including key virulence factors. Like other chemotaxis pathways, pili-mediated surface sensing results in a transient response amplified by a positive feedback that increases type IV pili activity, thereby promoting long-term surface attachment that can stimulate additional virulence and biofilm-inducing pathways. The methyl-accepting chemotaxis protein-like chemosensor PilJ directly interacts with the major pilin subunit PilA. Our results thus support a mechanochemical model where a chemosensory system measures the mechanically induced conformational changes in stretched type IV pili. These findings demonstrate that P. aeruginosa not only uses type IV pili for surface-specific twitching motility, but also as a sensor regulating surface-induced gene expression and pathogenicity.

Human Brain Organoids on a Chip Reveal the Physics of Folding.

PubMed

Karzbrun, Eyal; Kshirsagar, Aditya; Cohen, Sidney R; Hanna, Jacob H; Reiner, Orly

2018-05-01

Human brain wrinkling has been implicated in neurodevelopmental disorders and yet its origins remain unknown. Polymer gel models suggest that wrinkling emerges spontaneously due to compression forces arising during differential swelling, but these ideas have not been tested in a living system. Here, we report the appearance of surface wrinkles during the in vitro development and self-organization of human brain organoids in a micro-fabricated compartment that supports in situ imaging over a timescale of weeks. We observe the emergence of convolutions at a critical cell density and maximal nuclear strain, which are indicative of a mechanical instability. We identify two opposing forces contributing to differential growth: cytoskeletal contraction at the organoid core and cell-cycle-dependent nuclear expansion at the organoid perimeter. The wrinkling wavelength exhibits linear scaling with tissue thickness, consistent with balanced bending and stretching energies. Lissencephalic (smooth brain) organoids display reduced convolutions, modified scaling and a reduced elastic modulus. Although the mechanism here does not include the neuronal migration seen in in vivo , it models the physics of the folding brain remarkably well. Our on-chip approach offers a means for studying the emergent properties of organoid development, with implications for the embryonic human brain.

Human brain organoids on a chip reveal the physics of folding

NASA Astrophysics Data System (ADS)

Karzbrun, Eyal; Kshirsagar, Aditya; Cohen, Sidney R.; Hanna, Jacob H.; Reiner, Orly

2018-05-01

Human brain wrinkling has been implicated in neurodevelopmental disorders and yet its origins remain unknown. Polymer gel models suggest that wrinkling emerges spontaneously due to compression forces arising during differential swelling, but these ideas have not been tested in a living system. Here, we report the appearance of surface wrinkles during the in vitro development and self-organization of human brain organoids in a microfabricated compartment that supports in situ imaging over a timescale of weeks. We observe the emergence of convolutions at a critical cell density and maximal nuclear strain, which are indicative of a mechanical instability. We identify two opposing forces contributing to differential growth: cytoskeletal contraction at the organoid core and cell-cycle-dependent nuclear expansion at the organoid perimeter. The wrinkling wavelength exhibits linear scaling with tissue thickness, consistent with balanced bending and stretching energies. Lissencephalic (smooth brain) organoids display reduced convolutions, modified scaling and a reduced elastic modulus. Although the mechanism here does not include the neuronal migration seen in vivo, it models the physics of the folding brain remarkably well. Our on-chip approach offers a means for studying the emergent properties of organoid development, with implications for the embryonic human brain.

InSAR constraints on soil moisture evolution after the March 2015 extreme precipitation event in Chile.

PubMed

Scott, C P; Lohman, R B; Jordan, T E

2017-07-07

Constraints on soil moisture can guide agricultural practices, act as input into weather, flooding and climate models and inform water resource policies. Space-based interferometric synthetic aperture radar (InSAR) observations provide near-global coverage, even in the presence of clouds, of proxies for soil moisture derived from the amplitude and phase content of radar imagery. We describe results from a 1.5 year-long InSAR time series spanning the March, 2015 extreme precipitation event in the hyperarid Atacama desert of Chile, constraining the immediate increase in soil moisture and drying out over the following months, as well as the response to a later, smaller precipitation event. The inferred temporal evolution of soil moisture is remarkably consistent between independent, overlapping SAR tracks covering a region ~100 km in extent. The unusually large rain event, combined with the extensive spatial and temporal coverage of the SAR dataset, present an unprecedented opportunity to image the time-evolution of soil characteristics over different surface types. Constraints on the timescale of shallow water storage after precipitation events are increasingly valuable as global water resources continue to be stretched to their limits and communities continue to develop in flood-prone areas.

Single-shot spectroscopy of broadband Yb fiber laser

NASA Astrophysics Data System (ADS)

Suzuki, Masayuki; Yoneya, Shin; Kuroda, Hiroto

2017-02-01

We have experimentally reported on a real-time single-shot spectroscopy of a broadband Yb-doped fiber (YDF) laser which based on a nonlinear polarization evolution by using a time-stretched dispersive Fourier transformation technique. We have measured an 8000 consecutive single-shot spectra of mode locking and noise-like pulse (NLP), because our developed broadband YDF oscillator can individually operate the mode locking and NLP by controlling a pump LD power and angle of waveplates. A shot-to-shot spectral fluctuation was observed in NLP. For the investigation of pulse formation dynamics, we have measured the spectral evolution in an initial fluctuations of mode locked broadband YDF laser at an intracavity dispersion of 1500 and 6200 fs2 for the first time. In both case, a build-up time between cw and steady-state mode locking was estimated to be 50 us, the dynamics of spectral evolution between cw and mode locking, however, was completely different. A shot-to-shot strong spectral fluctuation, as can be seen in NLP spectra, was observed in the initial timescale of 20 us at the intracavity dispersion of 1500 fs2. These new findings would impact on understanding the birth of the broadband spectral formation in fiber laser oscillator.

Relativistic Dynamics and Mass Exchange in Binary Black Hole Mini-disks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bowen, Dennis B.; Campanelli, Manuela; Mewes, Vassilios

We present the first exploration of gas dynamics in a relativistic binary black hole (BH) system in which an accretion disk (a “mini-disk”) orbits each BH. We focus on 2D hydrodynamical studies of comparable-mass, non-spinning systems. Relativistic effects alter the dynamics of gas in this environment in several ways. Because the gravitational potential between the two BHs becomes shallower than in the Newtonian regime, the mini-disks stretch toward the L1 point and the amount of gas passing back and forth between the mini disks increases sharply with decreasing binary separation. This “sloshing” is quasi-periodically modulated at 2 and 2.75 timesmore » the binary orbital frequency, corresponding to timescales of hours to days for supermassive binary black holes (SMBBHs). In addition, relativistic effects add an m = 1 component to the tidally driven spiral waves in the disks that are purely m = 2 in Newtonian gravity; this component becomes dominant when the separation is ≲100 gravitational radii. Both the sloshing and the spiral waves have the potential to create distinctive radiation features that may uniquely mark SMBBHs in the relativistic regime.« less

Relativistic Dynamics and Mass Exchange in Binary Black Hole Mini-disks

NASA Astrophysics Data System (ADS)

Bowen, Dennis B.; Campanelli, Manuela; Krolik, Julian H.; Mewes, Vassilios; Noble, Scott C.

2017-03-01

We present the first exploration of gas dynamics in a relativistic binary black hole (BH) system in which an accretion disk (a “mini-disk”) orbits each BH. We focus on 2D hydrodynamical studies of comparable-mass, non-spinning systems. Relativistic effects alter the dynamics of gas in this environment in several ways. Because the gravitational potential between the two BHs becomes shallower than in the Newtonian regime, the mini-disks stretch toward the L1 point and the amount of gas passing back and forth between the mini disks increases sharply with decreasing binary separation. This “sloshing” is quasi-periodically modulated at 2 and 2.75 times the binary orbital frequency, corresponding to timescales of hours to days for supermassive binary black holes (SMBBHs). In addition, relativistic effects add an m = 1 component to the tidally driven spiral waves in the disks that are purely m = 2 in Newtonian gravity; this component becomes dominant when the separation is ≲100 gravitational radii. Both the sloshing and the spiral waves have the potential to create distinctive radiation features that may uniquely mark SMBBHs in the relativistic regime.

Resolution-dependent behavior of subgrid-scale vertical transport in the Zhang-McFarlane convection parameterization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xiao, Heng; Gustafson, Jr., William I.; Hagos, Samson M.

2015-04-18

With this study, to better understand the behavior of quasi-equilibrium-based convection parameterizations at higher resolution, we use a diagnostic framework to examine the resolution-dependence of subgrid-scale vertical transport of moist static energy as parameterized by the Zhang-McFarlane convection parameterization (ZM). Grid-scale input to ZM is supplied by coarsening output from cloud-resolving model (CRM) simulations onto subdomains ranging in size from 8 × 8 to 256 × 256 km 2s.

High-Pressure Balloon-Assisted Stretching of the Coracohumeral Ligament to Determine the Optimal Stretching Positions: A Cadaveric Study.

PubMed

Baek, Sora; Lee, Kyu Jin; Kim, Keewon; Han, Seung-Ho; Lee, U-Young; Lee, Kun-Jai; Chung, Sun Gun

2016-10-01

The coracohumeral ligament (CHL) is a thick capsular structure and markedly thickened when affected by adhesive capsulitis. Therapeutic stretching is the most commonly applied treatment for adhesive capsulitis, but optimal stretching postures for maximal therapeutic effects on the CHL have not been fully investigated. To investigate the most effective stretching direction for the CHL by measuring the stretching intensity in 5 different directions and to determine whether the stretching intervention resulted in loosening of the ligament by comparing the changes of CHL tightness before and after stretching. Biomechanical cadaver study. Academic institution cadaver laboratory. Nine fresh frozen cadaveric shoulders. A high-pressure balloon catheter inserted under the CHL and intraballoon pressure was measured, to evaluate CHL tightness without ligament damage as well as to augment and monitor stretching intensity. To find the optimal stretching direction, the glenohumeral joint was stretched from the neutral position into 5 directions sequentially under pressure-monitoring: flexion, extension [EX], external rotation [ER], EX+ER, and EX+ER+adduction [AD] directions. CHL tightness was determined by a surrogate parameter, the additional pressure created by the overlying CHL. The pressure increase (ΔP str ) by a specific directional stretch was considered as the stretching intensity. ΔP str by the 5 directions were mean (standard deviation) values of 0.03 ± 0.07 atm, 0.87 ± 1.31 atm, 1.13 ± 1.36 atm, 1.49 ± 1.32 atm, and 2.10 ± 1.70 atm, respectively, revealing the highest ΔP str by the EX+ER+AD stretch (P < .05). The balloon pressure by the overlying CHL was decreased from 0.45 ± 0.35 atm to 0.18 ± 0.14 atm (P = .012) before and after the stretching manipulation. EX+ER+AD of the glenohumeral joint resulted in the greatest increase in balloon pressure, implying that it could be the most effective stretching direction. A series of stretching manipulations assisted with an underlying pressure balloon were capable of decreasing CHL tightness. With further development and modification, high-pressure balloon-assisted stretching can be a potential therapeutic option to release tight CHL, including the advantage of augmenting and monitoring stretching intensity. II. Copyright © 2016 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

Effects on Hamstring Muscle Extensibility, Muscle Activity, and Balance of Different Stretching Techniques

PubMed Central

Lim, Kyoung-Il; Nam, Hyung-Chun; Jung, Kyoung-Sim

2014-01-01

[Purpose] The purpose of this study was to investigate the effects of two different stretching techniques on range of motion (ROM), muscle activation, and balance. [Subjects] For the present study, 48 adults with hamstring muscle tightness were recruited and randomly divided into three groups: a static stretching group (n=16), a PNF stretching group (n=16), a control group (n=16). [Methods] Both of the stretching techniques were applied to the hamstring once. Active knee extension angle, muscle activation during maximum voluntary isometric contraction (MVC), and static balance were measured before and after the application of each stretching technique. [Results] Both the static stretching and the PNF stretching groups showed significant increases in knee extension angle compared to the control group. However, there were no significant differences in muscle activation or balance between the groups. [Conclusion] Static stretching and PNF stretching techniques improved ROM without decrease in muscle activation, but neither of them exerted statistically significant effects on balance. PMID:24648633

The Relation Between Stretching Typology and Stretching Duration: The Effects on Range of Motion.

PubMed

Thomas, Ewan; Bianco, Antonino; Paoli, Antonio; Palma, Antonio

2018-04-01

Different stretching strategies and protocols are widely used to improve flexibility or maintain health, acting on the muscle tendon-unit, in order to improve the range of motion (ROM) of the joints. This review aims to evaluate the current body of literature in order to understand the relation between stretching typology and ROM, and secondly to evaluate if a relation exists between stretching volume (either as a single training session, weekly training and weekly frequency) and ROM, after long-term stretching. Twenty-three articles were considered eligible and included in the quantitative synthesis. All stretching typologies showed ROM improvements over a long-term period, however the static protocols showed significant gains (p<0.05) when compared to the ballistic or PNF protocols. Time spent stretching per week seems fundamental to elicit range of movement improvements when stretches are applied for at least or more than 5 min, whereas the time spent stretching within a single session does not seem to have significant effects for ROM gains. Weekly frequency is positively associated to ROM. Evaluated data indicates that performing stretching at least 5 days a week for at least 5 min per week using static stretching may be beneficial to promote ROM improvements. © Georg Thieme Verlag KG Stuttgart · New York.

Parameterizing by the Number of Numbers

NASA Astrophysics Data System (ADS)

Fellows, Michael R.; Gaspers, Serge; Rosamond, Frances A.

The usefulness of parameterized algorithmics has often depended on what Niedermeier has called "the art of problem parameterization". In this paper we introduce and explore a novel but general form of parameterization: the number of numbers. Several classic numerical problems, such as Subset Sum, Partition, 3-Partition, Numerical 3-Dimensional Matching, and Numerical Matching with Target Sums, have multisets of integers as input. We initiate the study of parameterizing these problems by the number of distinct integers in the input. We rely on an FPT result for Integer Linear Programming Feasibility to show that all the above-mentioned problems are fixed-parameter tractable when parameterized in this way. In various applied settings, problem inputs often consist in part of multisets of integers or multisets of weighted objects (such as edges in a graph, or jobs to be scheduled). Such number-of-numbers parameterized problems often reduce to subproblems about transition systems of various kinds, parameterized by the size of the system description. We consider several core problems of this kind relevant to number-of-numbers parameterization. Our main hardness result considers the problem: given a non-deterministic Mealy machine M (a finite state automaton outputting a letter on each transition), an input word x, and a census requirement c for the output word specifying how many times each letter of the output alphabet should be written, decide whether there exists a computation of M reading x that outputs a word y that meets the requirement c. We show that this problem is hard for W[1]. If the question is whether there exists an input word x such that a computation of M on x outputs a word that meets c, the problem becomes fixed-parameter tractable.

Ice-Cliff Failure via Retrogressive Slumping

NASA Astrophysics Data System (ADS)

Parizek, B. R.; Christianson, K.; Alley, R. B.; Voytenko, D.; Vankova, I.; Dixon, T. H.; Holland, D.

2016-12-01

The magnitude and rate of future sea-level rise from warming-induced ice-sheet shrinkage remain notably uncertain. Removal of most of an ice sheet by surface melting alone requires centuries to millennia. Oceanic warming may accelerate loss by removing buttressing ice shelves and thereby speeding flow of non-floating ice into the ocean, but, until recently, modeled timescales for major dynamic ice-sheet shrinkage were centuries or longer. Beyond certain thresholds, however, observations show that warming removes floating ice shelves, leaving grounded ice cliffs from which icebergs break off directly. Cliffs higher than some limit experience rapid structural failure. Recent parameterization of this process in a comprehensive ice-flow model produced much faster sea-level rise from future rapid warming than in previous modeling studies, through formation and retreat of tall ice cliffs. Fully physical representations of this process are not yet available, however. Here, we use modeling guided by terrestrial radar data from Helheim Glacier, Greenland to show that cliffs will fail by slumping and trigger rapid retreat at a threshold height that, in crevassed ice with surface melting, may be only slightly above the 100-m maximum observed today, but may be roughly twice that (180-275 m) in mechanically-competent ice under well-drained or low-melt conditions.

Dynamics and Chemistry in Jovian Atmospheres: 2D Hydrodynamical Simulations

NASA Astrophysics Data System (ADS)

Bordwell, B. R.; Brown, B. P.; Oishi, J.

2016-12-01

A key component of our understanding of the formation and evolution of planetary systems is chemical composition. Problematically, however, in the atmospheres of cooler gas giants, dynamics on the same timescale as chemical reactions pull molecular abundances out of thermochemical equilibrium. These disequilibrium abundances are treated using what is known as the "quench" approximation, based upon the mixing length theory of convection. The validity of this approximation is questionable, though, as the atmospheres of gas giants encompass two distinct dynamic regimes: convective and radiative. To resolve this issue, we conduct 2D hydrodynamical simulations using the state-of-the-art pseudospectral simulation framework Dedalus. In these simulations, we solve the fully compressible equations of fluid motion in a local slab geometry that mimics the structure of a planetary atmosphere (convective zone underlying a radiative zone). Through the inclusion of passive tracers, we explore the transport properties of both regimes, and assess the validity of the classical eddy diffusion parameterization. With the addition of active tracers, we examine the interactions between dynamical and chemical processes, and generate prescriptions for the observational community. By providing insight into mixing and feedback mechanisms in Jovian atmospheres, this research lays a solid foundation for future global simulations and the construction of physically-sound models for current and future observations.

The CE-Way of Thinking: "All Is Relative!".

PubMed

Schmitt-Kopplin, Philippe; Fekete, Agnes

2016-01-01

Over the last two decades the development of capillary electrophoresis instruments lead to systems with programmable sampler, separation column, separation buffer, and detection devices comparable visually in many aspects to the setup of classical chromatography.Two processes make capillary electrophoresis essentially different from chromatography and are the basis of the CE-way of thinking, namely, the injection type and the liquid flow within the capillary. (1) When the injection is made hydrodynamically (such as in most of the found applications in the literature), the injected volumes are directly dependent on the type and size of the separation capillary. (2) The buffer velocity is not pressure driven as in liquid chromatography but electrokinetically governed by the quality of the capillary surface (separation buffer dependant surface charge) inducing an electroosmotic flow (EOF). The EOF undergoes small variations and is not necessarily identical from one separation or day to the other. The direct consequence is an apparent nonreproducible migration time of the analytes, even though the own velocity of the ions is the same.The effective mobility (field strength normalized velocity) of the ions is a possible parameterization from acquired timescale to effective mobility-scale electropherograms leading to a reproducible visualization and better quantification with a direct relation to structural characters of the analytes (i.e., charge and size-see chapter on semiempirical modelization).

Parameterized Cross Sections for Pion Production in Proton-Proton Collisions

NASA Technical Reports Server (NTRS)

Blattnig, Steve R.; Swaminathan, Sudha R.; Kruger, Adam T.; Ngom, Moussa; Norbury, John W.; Tripathi, R. K.

2000-01-01

An accurate knowledge of cross sections for pion production in proton-proton collisions finds wide application in particle physics, astrophysics, cosmic ray physics, and space radiation problems, especially in situations where an incident proton is transported through some medium and knowledge of the output particle spectrum is required when given the input spectrum. In these cases, accurate parameterizations of the cross sections are desired. In this paper much of the experimental data are reviewed and compared with a wide variety of different cross section parameterizations. Therefore, parameterizations of neutral and charged pion cross sections are provided that give a very accurate description of the experimental data. Lorentz invariant differential cross sections, spectral distributions, and total cross section parameterizations are presented.

Collaborative Research: Reducing tropical precipitation biases in CESM — Tests of unified parameterizations with ARM observations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larson, Vincent; Gettelman, Andrew; Morrison, Hugh

In state-of-the-art climate models, each cloud type is treated using its own separate cloud parameterization and its own separate microphysics parameterization. This use of separate schemes for separate cloud regimes is undesirable because it is theoretically unfounded, it hampers interpretation of results, and it leads to the temptation to overtune parameters. In this grant, we are creating a climate model that contains a unified cloud parameterization and a unified microphysics parameterization. This model will be used to address the problems of excessive frequency of drizzle in climate models and excessively early onset of deep convection in the Tropics over land.more » The resulting model will be compared with ARM observations.« less

Ice-nucleating particle emissions from photochemically aged diesel and biodiesel exhaust

NASA Astrophysics Data System (ADS)

Schill, G. P.; Jathar, S. H.; Kodros, J. K.; Levin, E. J. T.; Galang, A. M.; Friedman, B.; Link, M. F.; Farmer, D. K.; Pierce, J. R.; Kreidenweis, S. M.; DeMott, P. J.

2016-05-01

Immersion-mode ice-nucleating particle (INP) concentrations from an off-road diesel engine were measured using a continuous-flow diffusion chamber at -30°C. Both petrodiesel and biodiesel were utilized, and the exhaust was aged up to 1.5 photochemically equivalent days using an oxidative flow reactor. We found that aged and unaged diesel exhaust of both fuels is not likely to contribute to atmospheric INP concentrations at mixed-phase cloud conditions. To explore this further, a new limit-of-detection parameterization for ice nucleation on diesel exhaust was developed. Using a global-chemical transport model, potential black carbon INP (INPBC) concentrations were determined using a current literature INPBC parameterization and the limit-of-detection parameterization. Model outputs indicate that the current literature parameterization likely overemphasizes INPBC concentrations, especially in the Northern Hemisphere. These results highlight the need to integrate new INPBC parameterizations into global climate models as generalized INPBC parameterizations are not valid for diesel exhaust.

Radiative flux and forcing parameterization error in aerosol-free clear skies

DOE PAGES

Pincus, Robert; Mlawer, Eli J.; Oreopoulos, Lazaros; ...

2015-07-03

This article reports on the accuracy in aerosol- and cloud-free conditions of the radiation parameterizations used in climate models. Accuracy is assessed relative to observationally validated reference models for fluxes under present-day conditions and forcing (flux changes) from quadrupled concentrations of carbon dioxide. Agreement among reference models is typically within 1 W/m 2, while parameterized calculations are roughly half as accurate in the longwave and even less accurate, and more variable, in the shortwave. Absorption of shortwave radiation is underestimated by most parameterizations in the present day and has relatively large errors in forcing. Error in present-day conditions is essentiallymore » unrelated to error in forcing calculations. Recent revisions to parameterizations have reduced error in most cases. As a result, a dependence on atmospheric conditions, including integrated water vapor, means that global estimates of parameterization error relevant for the radiative forcing of climate change will require much more ambitious calculations.« less

Get up and Stretch

ERIC Educational Resources Information Center

Crupi, Jeffrey

2004-01-01

Daily stretching has many benefits for one's body. It can relieve stress and tension, it increases flexibility and it can help prevent injuries. There are many stretching exercises that a teacher can do with his or her students to help promote daily stretching routines. In this article, the author presents several stretching exercises and some…

Stretching & Flexibility: An Interactive Encyclopedia of Stretching. [CD-ROM].

ERIC Educational Resources Information Center

2002

This CD-ROM offers 140 different stretches in full-motion video sequences. It focuses on the proper techniques for overall physical fitness, injury prevention and rehabilitation, and 23 different sports (e.g., golf, running, soccer, skiing, climbing, football, and baseball). Topics include stretching for sports; stretching awareness and education…

CURRENT CONCEPTS IN MUSCLE STRETCHING FOR EXERCISE AND REHABILITATION

PubMed Central

2012-01-01

Stretching is a common activity used by athletes, older adults, rehabilitation patients, and anyone participating in a fitness program. While the benefits of stretching are known, controversy remains about the best type of stretching for a particular goal or outcome. The purpose of this clinical commentary is to discuss the current concepts of muscle stretching interventions and summarize the evidence related to stretching as used in both exercise and rehabilitation. PMID:22319684

STRETCHING IMPACTS INFLAMMATION RESOLUTION IN CONNECTIVE TISSUE

PubMed Central

Berrueta, Lisbeth; Muskaj, Igla; Olenich, Sara; Butler, Taylor; Badger, Gary J.; Colas, Romain A.; Spite, Matthew; Serhan, Charles N.; Langevin, Helene M.

2016-01-01

Acute inflammation is accompanied from its outset by the release of specialized pro-resolving mediators (SPMs), including resolvins, that orchestrate the resolution of local inflammation. We showed earlier that, in rats with subcutaneous inflammation of the back induced by carrageenan, stretching for 10 minutes twice daily reduced inflammation and improved pain, two weeks after carrageenan injection. In this study, we hypothesized that stretching of connective tissue activates local pro-resolving mechanisms within the tissue in the acute phase of inflammation. In rats injected with carrageenan and randomized to stretch vs. no stretch for 48 hours, stretching reduced inflammatory lesion thickness and neutrophil count, and increased resolvin (RvD1) concentrations within lesions. Furthermore, subcutaneous resolvin injection mimicked the effect of stretching. In ex vivo experiments, stretching of connective tissue reduced the migration of neutrophils and increased tissue RvD1 concentration. These results demonstrate a direct mechanical impact of stretching on inflammation-regulation mechanisms within connective tissue. PMID:26588184

Interset stretching does not influence the kinematic profile of consecutive bench-press sets.

PubMed

García-López, David; Izquierdo, Mikel; Rodríguez, Sergio; González-Calvo, Gustavo; Sainz, Nuria; Abadía, Olaia; Herrero, Azael J

2010-05-01

This study was undertaken to examine the role of interset stretching on the time course of acceleration portion AP and mean velocity profile during the concentric phase of 2 bench-press sets with a submaximal load (60% of the 1 repetition maximum). Twenty-five college students carried out, in 3 different days, 2 consecutive bench-press sets leading to failure, performing between sets static stretching, ballistic stretching, or no stretching. Acceleration portion and lifting velocity patterns of the concentric phase were not altered during the second set, regardless of the stretching treatment performed. However, when velocity was expressed in absolute terms, static stretching reduced significantly (p <0.05) the average lifting velocity during the second set compared to the first one. Therefore, if maintenance of a high absolute velocity over consecutive sets is important for training-related adaptations, static stretching should be avoided or replaced by ballistic stretching.

Dependence of Actuation Strain of Dielectric Elastomer on Equi-biaxial, Pure Shear and Uniaxial Modes of Pre-stretching

NASA Astrophysics Data System (ADS)

Kumar, Ajeet; Ahmad, Dilshad; Patra, Karali

2018-02-01

A dielectric elastomer is capable of large deformation under three basic modes of deformation: equi-biaxial, pure shear and uniaxial. Pre-stretching of dielectric elastomer improves the actuation strain appreciably. Experimental results shows that pre-stretching using equal biaxial mode can result to higher actuation strain compared to other two modes of stretching, i.e., uniaxial and pure shear. However, analysis of the experimental results shows that the actuation strain is independent of the modes of pre-stretching rather it is dependent upon the thickness stretch. For same thickness stretch at a particular voltage, the actuation strain is almost similar for all pre-stretching modes. Power trend lines are obtained to predict the actuation strain at any thickness stretch for a particular voltage. The present analysis opens the door to easily design the actuators, sensors and energy harvesting devices.

Levator Ani Muscle Stretch Induced by Simulated Vaginal Birth

PubMed Central

Lien, Kuo-Cheng; Mooney, Brian; DeLancey, John O. L.; Ashton-Miller, James A.

2005-01-01

OBJECTIVE: To develop a three-dimensional computer model to predict levator ani muscle stretch during vaginal birth. METHODS: Serial magnetic resonance images from a healthy nulliparous 34-year-old woman, published anatomic data, and engineering graphics software were used to construct a structural model of the levator ani muscles along with related passive tissues. The model was used to quantify pelvic floor muscle stretch induced during the second stage of labor as a model fetal head progressively engaged and then stretched the iliococcygeus, pubococcygeus, and puborectalis muscles. RESULTS: The largest tissue strain reached a stretch ratio (tissue length under stretch/original tissue length) of 3.26 in medial pubococcygeus muscle, the shortest, most medial and ventral levator ani muscle. Regions of the ileococcygeus, pubococcygeus, and puborectalis muscles reached maximal stretch ratios of 2.73, 2.50, and 2.28, respectively. Tissue stretch ratios were proportional to fetal head size: For example, increasing fetal head diameter by 9% increased medial pubococcygeus stretch by the same amount. CONCLUSION: The medial pubococcygeus muscles undergo the largest stretch of any levator ani muscles during vaginal birth. They are therefore at the greatest risk for stretch-related injury. PMID:14704241

Level of functional capacities following soccer-specific warm-up methods among elite collegiate soccer players.

PubMed

Vazini Taher, Amir; Parnow, Abdolhossein

2017-05-01

Different methods of warm-up may have implications in improving various aspects of soccer performance. The present study aimed to investigate acute effects of soccer specific warm-up protocols on functional performance tests. This study using randomized within-subject design, investigated the performance of 22 collegiate elite soccer player following soccer specific warm-ups using dynamic stretching, static stretching, and FIFA 11+ program. Post warm-up examinations consisted: 1) Illinois Agility Test; 2) vertical jump; 3) 30 meter sprint; 4) consecutive turns; 5) flexibility of knee. Vertical jump performance was significantly lower following static stretching, as compared to dynamic stretching (P=0.005). Sprint performance declined significantly following static stretching as compared to FIFA 11+ (P=0.023). Agility time was significantly faster following dynamic stretching as compared to FIFA 11+ (P=0.001) and static stretching (P=0.001). Knee flexibility scores were significantly improved following the static stretching as compared to dynamic stretching (P=016). No significant difference was observed for consecutive turns between three warm-up protocol. The present finding showed that a soccer specific warm-up protocol relied on dynamic stretching is preferable in enhancing performance as compared to protocols relying on static stretches and FIFA 11+ program. Investigators suggest that while different soccer specific warm-up protocols have varied types of effects on performance, acute effects of dynamic stretching on performance in elite soccer players are assured, however application of static stretching in reducing muscle stiffness is demonstrated.

Experimental constraints on the deformation and breakup of injected magma

NASA Astrophysics Data System (ADS)

Hodge, Kirsten F.; Carazzo, Guillaume; Jellinek, A. Mark

2012-04-01

The injection, breakup and stirring of dikes entering convecting silicic magma chambers can govern how they grow and differentiate, as well as influence their potential for eruption at the surface. Enclaves observed in plutons may preserve a record of this process and, thus, identifying and understanding the physical processes underlying their formation is a crucial issue in volcanology. We use laboratory experiments and scaling theory to investigate the mechanical and rheological conditions leading to the deformation and breakup of analog crystal-rich dikes injected as discrete plumes that descend into an underlying imposed shear flow. To scale the experiments and map the results across a wide range of natural conditions we define the ratio S of the timescale for the growth of a gravitational Rayleigh-Taylor (R-T) instability of the sheared, injected material to the timescale for settling through the fluid layer and the ratio Y of the timescales for shearing and lateral disaggregation of the particle-fluid mixture (yielding). At low S (< 3) and high Y (> 40), descending plumes are stretched and tilted before undergoing R-T instability, forming drips with a wavelength that is comparable to the initial diameter of the injection. At low Y (< 40) and S values that increase from ∼ 3 as Y → 0, an injection yields in tension before a R-T instability can grow, forming discrete particle-fluid blobs that are much smaller than the initial injection diameter and separated by thin filaments of the original mixture. At high S (> 3) and high Y (> 40), injections remain intact as they settle through the layer and pond at the floor. Applied to magma chambers, our results do not support the production of a continuum of enclave sizes. Indeed, from scaling analyses we expect the two breakup regimes to form distinct size populations: Whereas enclaves formed in the R-T regime will be comparable to the injection size, those formed in the tension regime will be much smaller. We show that enclave size distributions observed in the field can potentially be used to infer the Y - S conditions for the magma chamber at the time of injection. In addition, these observations can constrain aspects of the styles of flow, stirring, and mixing within the magma chamber, as well as the rheological contrast between the injected and host magma at the time of enclave formation. Our work shows that the contrast in composition between the injected and host magmas will have a strong effect on the mingling structures that are likely to be generated.

[Formula: see text] regularity properties of singular parameterizations in isogeometric analysis.

PubMed

Takacs, T; Jüttler, B

2012-11-01

Isogeometric analysis (IGA) is a numerical simulation method which is directly based on the NURBS-based representation of CAD models. It exploits the tensor-product structure of 2- or 3-dimensional NURBS objects to parameterize the physical domain. Hence the physical domain is parameterized with respect to a rectangle or to a cube. Consequently, singularly parameterized NURBS surfaces and NURBS volumes are needed in order to represent non-quadrangular or non-hexahedral domains without splitting, thereby producing a very compact and convenient representation. The Galerkin projection introduces finite-dimensional spaces of test functions in the weak formulation of partial differential equations. In particular, the test functions used in isogeometric analysis are obtained by composing the inverse of the domain parameterization with the NURBS basis functions. In the case of singular parameterizations, however, some of the resulting test functions do not necessarily fulfill the required regularity properties. Consequently, numerical methods for the solution of partial differential equations cannot be applied properly. We discuss the regularity properties of the test functions. For one- and two-dimensional domains we consider several important classes of singularities of NURBS parameterizations. For specific cases we derive additional conditions which guarantee the regularity of the test functions. In addition we present a modification scheme for the discretized function space in case of insufficient regularity. It is also shown how these results can be applied for computational domains in higher dimensions that can be parameterized via sweeping.

Parameterization Interactions in Global Aquaplanet Simulations

NASA Astrophysics Data System (ADS)

Bhattacharya, Ritthik; Bordoni, Simona; Suselj, Kay; Teixeira, João.

2018-02-01

Global climate simulations rely on parameterizations of physical processes that have scales smaller than the resolved ones. In the atmosphere, these parameterizations represent moist convection, boundary layer turbulence and convection, cloud microphysics, longwave and shortwave radiation, and the interaction with the land and ocean surface. These parameterizations can generate different climates involving a wide range of interactions among parameterizations and between the parameterizations and the resolved dynamics. To gain a simplified understanding of a subset of these interactions, we perform aquaplanet simulations with the global version of the Weather Research and Forecasting (WRF) model employing a range (in terms of properties) of moist convection and boundary layer (BL) parameterizations. Significant differences are noted in the simulated precipitation amounts, its partitioning between convective and large-scale precipitation, as well as in the radiative impacts. These differences arise from the way the subcloud physics interacts with convection, both directly and through various pathways involving the large-scale dynamics and the boundary layer, convection, and clouds. A detailed analysis of the profiles of the different tendencies (from the different physical processes) for both potential temperature and water vapor is performed. While different combinations of convection and boundary layer parameterizations can lead to different climates, a key conclusion of this study is that similar climates can be simulated with model versions that are different in terms of the partitioning of the tendencies: the vertically distributed energy and water balances in the tropics can be obtained with significantly different profiles of large-scale, convection, and cloud microphysics tendencies.

On testing two major cumulus parameterization schemes using the CSU Regional Atmospheric Modeling System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kao, C.Y.J.; Bossert, J.E.; Winterkamp, J.

1993-10-01

One of the objectives of the DOE ARM Program is to improve the parameterization of clouds in general circulation models (GCMs). The approach taken in this research is two fold. We first examine the behavior of cumulus parameterization schemes by comparing their performance against the results from explicit cloud simulations with state-of-the-art microphysics. This is conducted in a two-dimensional (2-D) configuration of an idealized convective system. We then apply the cumulus parameterization schemes to realistic three-dimensional (3-D) simulations over the western US for a case with an enormous amount of convection in an extended period of five days. In themore » 2-D idealized tests, cloud effects are parameterized in the ``parameterization cases`` with a coarse resolution, whereas each cloud is explicitly resolved by the ``microphysics cases`` with a much finer resolution. Thus, the capability of the parameterization schemes in reproducing the growth and life cycle of a convective system can then be evaluated. These 2-D tests will form the basis for further 3-D realistic simulations which have the model resolution equivalent to that of the next generation of GCMs. Two cumulus parameterizations are used in this research: the Arakawa-Schubert (A-S) scheme (Arakawa and Schubert, 1974) used in Kao and Ogura (1987) and the Kuo scheme (Kuo, 1974) used in Tremback (1990). The numerical model used in this research is the Regional Atmospheric Modeling System (RAMS) developed at Colorado State University (CSU).« less

Brain Surface Conformal Parameterization Using Riemann Surface Structure

PubMed Central

Wang, Yalin; Lui, Lok Ming; Gu, Xianfeng; Hayashi, Kiralee M.; Chan, Tony F.; Toga, Arthur W.; Thompson, Paul M.; Yau, Shing-Tung

2011-01-01

In medical imaging, parameterized 3-D surface models are useful for anatomical modeling and visualization, statistical comparisons of anatomy, and surface-based registration and signal processing. Here we introduce a parameterization method based on Riemann surface structure, which uses a special curvilinear net structure (conformal net) to partition the surface into a set of patches that can each be conformally mapped to a parallelogram. The resulting surface subdivision and the parameterizations of the components are intrinsic and stable (their solutions tend to be smooth functions and the boundary conditions of the Dirichlet problem can be enforced). Conformal parameterization also helps transform partial differential equations (PDEs) that may be defined on 3-D brain surface manifolds to modified PDEs on a two-dimensional parameter domain. Since the Jacobian matrix of a conformal parameterization is diagonal, the modified PDE on the parameter domain is readily solved. To illustrate our techniques, we computed parameterizations for several types of anatomical surfaces in 3-D magnetic resonance imaging scans of the brain, including the cerebral cortex, hippocampi, and lateral ventricles. For surfaces that are topologically homeomorphic to each other and have similar geometrical structures, we show that the parameterization results are consistent and the subdivided surfaces can be matched to each other. Finally, we present an automatic sulcal landmark location algorithm by solving PDEs on cortical surfaces. The landmark detection results are used as constraints for building conformal maps between surfaces that also match explicitly defined landmarks. PMID:17679336

Recent Advances in High-Resolution Regional Climate Modeling at the U.S. Environmental Protection Agency

NASA Astrophysics Data System (ADS)

Alapaty, Kiran; Bullock, O. Russell; Herwehe, Jerold; Spero, Tanya; Nolte, Christopher; Mallard, Megan

2014-05-01

The Regional Climate Modeling Team at the U.S. Environmental Protection Agency has been improving the quality of regional climate fields generated by the Weather Research and Forecasting (WRF) model. Active areas of research include improving core physics within the WRF model and adapting the physics for regional climate applications, improving the representation of inland lakes that are unresolved by the driving fields, evaluating nudging strategies, and devising techniques to demonstrate value added by dynamical downscaling. These research efforts have been conducted using reanalysis data as driving fields, and then their results have been applied to downscale data from global climate models. The goals of this work are to equip environmental managers and policy/decision makers in the U.S. with science, tools, and data to inform decisions related to adapting to and mitigating the potential impacts of climate change on air quality, ecosystems, and human health. Our presentation will focus mainly on one area of the Team's research: Development and testing of a seamless convection parameterization scheme. For the continental U.S., one of the impediments to high-resolution (~3 to 15 km) climate modeling is related to the lack of a seamless convection parameterization that works across many scales. Since many convection schemes are not developed to work at those "gray scales", they often lead to excessive precipitation during warm periods (e.g., summer). The Kain-Fritsch (KF) convection parameterization in the WRF model has been updated such that it can be used seamlessly across spatial scales down to ~1 km grid spacing. First, we introduced subgrid-scale cloud and radiation interactions that had not been previously considered in the KF scheme. Then, a scaling parameter was developed to introduce scale-dependency in the KF scheme for use with various processes. In addition, we developed new formulations for: (1) convective adjustment timescale; (2) entrainment of environmental air; (3) impacts of convective updraft on grid-scale vertical velocity; (4) convective cloud microphysics; (5) stabilizing capacity; (6) elimination of double counting of precipitation; and (7) estimation of updraft mass flux at the lifting condensation level. Some of these scale-dependent formulations make the KF scheme operable at all scales up to about sub-kilometer grid resolution. In this presentation, regional climate simulations using the WRF model will be presented to demonstrate the effects of these changes to the KF scheme. Additionally, we briefly present results obtained from the improved representation of inland lakes, various nudging strategies, and added value of dynamical downscaling of regional climate. Requesting for a plenary talk for the session: "Regional climate modeling, including CORDEX" (session number CL6.4) at the EGU 2014 General Assembly, to be held 27 April - 2 May 2014 in Vienna, Austria.

Impact of Apex Model parameterization strategy on estimated benefit of conservation practices

USDA-ARS?s Scientific Manuscript database

Three parameterized Agriculture Policy Environmental eXtender (APEX) models for corn-soybean rotation on clay pan soils were developed with the objectives, 1. Evaluate model performance of three parameterization strategies on a validation watershed; and 2. Compare predictions of water quality benefi...

Single-Column Modeling, GCM Parameterizations and Atmospheric Radiation Measurement Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Somerville, R.C.J.; Iacobellis, S.F.

2005-03-18

Our overall goal is identical to that of the Atmospheric Radiation Measurement (ARM) Program: the development of new and improved parameterizations of cloud-radiation effects and related processes, using ARM data at all three ARM sites, and the implementation and testing of these parameterizations in global and regional models. To test recently developed prognostic parameterizations based on detailed cloud microphysics, we have first compared single-column model (SCM) output with ARM observations at the Southern Great Plains (SGP), North Slope of Alaska (NSA) and Topical Western Pacific (TWP) sites. We focus on the predicted cloud amounts and on a suite of radiativemore » quantities strongly dependent on clouds, such as downwelling surface shortwave radiation. Our results demonstrate the superiority of parameterizations based on comprehensive treatments of cloud microphysics and cloud-radiative interactions. At the SGP and NSA sites, the SCM results simulate the ARM measurements well and are demonstrably more realistic than typical parameterizations found in conventional operational forecasting models. At the TWP site, the model performance depends strongly on details of the scheme, and the results of our diagnostic tests suggest ways to develop improved parameterizations better suited to simulating cloud-radiation interactions in the tropics generally. These advances have made it possible to take the next step and build on this progress, by incorporating our parameterization schemes in state-of-the-art 3D atmospheric models, and diagnosing and evaluating the results using independent data. Because the improved cloud-radiation results have been obtained largely via implementing detailed and physically comprehensive cloud microphysics, we anticipate that improved predictions of hydrologic cycle components, and hence of precipitation, may also be achievable. We are currently testing the performance of our ARM-based parameterizations in state-of-the--art global and regional models. One fruitful strategy for evaluating advances in parameterizations has turned out to be using short-range numerical weather prediction as a test-bed within which to implement and improve parameterizations for modeling and predicting climate variability. The global models we have used to date are the CAM atmospheric component of the National Center for Atmospheric Research (NCAR) CCSM climate model as well as the National Centers for Environmental Prediction (NCEP) numerical weather prediction model, thus allowing testing in both climate simulation and numerical weather prediction modes. We present detailed results of these tests, demonstrating the sensitivity of model performance to changes in parameterizations.« less

A Discrete Electromechanical Model for Human Cardiac Tissue: Effects of Stretch-Activated Currents and Stretch Conditions on Restitution Properties and Spiral Wave Dynamics

PubMed Central

Weise, Louis D.; Panfilov, Alexander V.

2013-01-01

We introduce an electromechanical model for human cardiac tissue which couples a biophysical model of cardiac excitation (Tusscher, Noble, Noble, Panfilov, 2006) and tension development (adjusted Niederer, Hunter, Smith, 2006 model) with a discrete elastic mass-lattice model. The equations for the excitation processes are solved with a finite difference approach, and the equations of the mass-lattice model are solved using Verlet integration. This allows the coupled problem to be solved with high numerical resolution. Passive mechanical properties of the mass-lattice model are described by a generalized Hooke's law for finite deformations (Seth material). Active mechanical contraction is initiated by changes of the intracellular calcium concentration, which is a variable of the electrical model. Mechanical deformation feeds back on the electrophysiology via stretch-activated ion channels whose conductivity is controlled by the local stretch of the medium. We apply the model to study how stretch-activated currents affect the action potential shape, restitution properties, and dynamics of spiral waves, under constant stretch, and dynamic stretch caused by active mechanical contraction. We find that stretch conditions substantially affect these properties via stretch-activated currents. In constantly stretched medium, we observe a substantial decrease in conduction velocity, and an increase of action potential duration; whereas, with dynamic stretch, action potential duration is increased only slightly, and the conduction velocity restitution curve becomes biphasic. Moreover, in constantly stretched medium, we find an increase of the core size and period of a spiral wave, but no change in rotation dynamics; in contrast, in the dynamically stretching medium, we observe spiral drift. Our results may be important to understand how altered stretch conditions affect the heart's functioning. PMID:23527160

A discrete electromechanical model for human cardiac tissue: effects of stretch-activated currents and stretch conditions on restitution properties and spiral wave dynamics.

PubMed

Weise, Louis D; Panfilov, Alexander V

2013-01-01

We introduce an electromechanical model for human cardiac tissue which couples a biophysical model of cardiac excitation (Tusscher, Noble, Noble, Panfilov, 2006) and tension development (adjusted Niederer, Hunter, Smith, 2006 model) with a discrete elastic mass-lattice model. The equations for the excitation processes are solved with a finite difference approach, and the equations of the mass-lattice model are solved using Verlet integration. This allows the coupled problem to be solved with high numerical resolution. Passive mechanical properties of the mass-lattice model are described by a generalized Hooke's law for finite deformations (Seth material). Active mechanical contraction is initiated by changes of the intracellular calcium concentration, which is a variable of the electrical model. Mechanical deformation feeds back on the electrophysiology via stretch-activated ion channels whose conductivity is controlled by the local stretch of the medium. We apply the model to study how stretch-activated currents affect the action potential shape, restitution properties, and dynamics of spiral waves, under constant stretch, and dynamic stretch caused by active mechanical contraction. We find that stretch conditions substantially affect these properties via stretch-activated currents. In constantly stretched medium, we observe a substantial decrease in conduction velocity, and an increase of action potential duration; whereas, with dynamic stretch, action potential duration is increased only slightly, and the conduction velocity restitution curve becomes biphasic. Moreover, in constantly stretched medium, we find an increase of the core size and period of a spiral wave, but no change in rotation dynamics; in contrast, in the dynamically stretching medium, we observe spiral drift. Our results may be important to understand how altered stretch conditions affect the heart's functioning.

STRETCH-DEPENDENT SENSITIZATION OF POST-JUNCTIONAL NEURAL EFFECTORS IN COLONIC MUSCLES

PubMed Central

Won, Kyung-Jong; Sanders, Kenton M.; Ward, Sean M.

2012-01-01

Background The colon undergoes distension-induced changes in motor activity as luminal contents or feces increases wall pressure. Input from enteric motor neurons regulates motility. Here we examined stretch-dependent responses in circular muscle strips of murine colon. Methods Length-ramps (6–31μm s−1) were applied in the axis of the circular muscle layer in a controlled manner until 5 mN isometric force was reached. Key Results Length-ramps produced transient membrane potential hyperpolarizations and attenuation of action potential (AP) complexes. Responses were reproducible when ramps were applied every 30s. Stretch-dependent hyperpolarization was blocked by TTX, suggesting AP-dependent release of inhibitory neurotransmitter(s). Atropine did not potentiate stretch-induced hyperpolarizations, but increased compliance of the circular layer. L-NNA inhibited stretch-dependent hyperpolarization and decreased muscle compliance, suggesting release of NO mediates stretch-dependent inhibition. Control membrane potential was restored by the NO donor SNP. Stretch-dependent hyperpolarizations were blocked by L-methionine, an inhibitor of stretch-dependent K+ (SDK) channels in colonic muscles. Loss of ICC, elicited by Kit neutralizing antibody, also inhibited responses to stretch. In presence of L-NNA and apamin, stretch responses became excitatory and were characterized by membrane depolarization and increased AP firing. A neurokinin-1 receptor antagonist inhibited this stretch-dependent increase in excitability. Conclusions & Inferences Our data show that stretch-dependent responses in colonic muscles require tonic firing of enteric inhibitory neurons, but reflex activation of neurons does not appear to be necessary. NO causes activation of SDK channels, and stretch of muscles further activates these channels, explaining the inhibitory response to stretch in colonic muscle strips. PMID:23279087

Optimizing an Intermittent Stretch Paradigm Using ERK1/2 Phosphorylation Results in Increased Collagen Synthesis in Engineered Ligaments

PubMed Central

Paxton, Jennifer Z.; Hagerty, Paul; Andrick, Jonathan J.

2012-01-01

Dynamic mechanical input is believed to play a critical role in the development of functional musculoskeletal tissues. To study this phenomenon, cyclic uniaxial mechanical stretch was applied to engineered ligaments using a custom-built bioreactor and the effects of different stretch frequency, amplitude, and duration were determined. Stretch acutely increased the phosphorylation of p38 (3.5±0.74-fold), S6K1 (3.9±0.19-fold), and ERK1/2 (2.45±0.32-fold). The phosphorylation of ERK1/2 was dependent on time, rather than on frequency or amplitude, within these constructs. ERK1/2 phosphorylation was similar following stretch at frequencies from 0.1 to 1 Hz and amplitudes from 2.5% to 15%, whereas phosphorylation reached maximal levels at 10 min of stretch and returned toward basal within 60 min of stretch. Following a single 10-min bout of cyclic stretch, the cells remained refractory to a second stretch for up to 6 h. Using the phosphorylation of ERK1/2 as a guide, the optimum stretch paradigm was hypothesized to be 10 min of stretch at 2.5% of resting length repeated every 6 h. Consistent with this hypothesis, 7 days of stretch using this optimized intermittent stretch program increased the collagen content of the grafts more than a continuous stretch program (CTL=3.1%±0.44%; CONT=4.8%±0.30%; and INT=5.9%±0.56%). These results suggest that short infrequent bouts of loading are optimal for improving engineered tendon and ligament physiology. PMID:21902469

The relevance of stretch intensity and position—a systematic review

PubMed Central

Apostolopoulos, Nikos; Metsios, George S.; Flouris, Andreas D.; Koutedakis, Yiannis; Wyon, Matthew A.

2015-01-01

Stretching exercises to increase the range of motion (ROM) of joints have been used by sports coaches and medical professionals for improving performance and rehabilitation. The ability of connective and muscular tissues to change their architecture in response to stretching is important for their proper function, repair, and performance. Given the dearth of relevant data in the literature, this review examined two key elements of stretching: stretch intensity and stretch position; and their significance to ROM, delayed onset muscle soreness (DOMS), and inflammation in different populations. A search of three databases, Pub-Med, Google Scholar, and Cochrane Reviews, identified 152 articles, which were subsequently categorized into four groups: athletes (24), clinical (29), elderly (12), and general population (87). The use of different populations facilitated a wider examination of the stretching components and their effects. All 152 articles incorporated information regarding duration, frequency and stretch position, whereas only 79 referred to the intensity of stretching and 22 of these 79 studies were deemed high quality. It appears that the intensity of stretching is relatively under-researched, and the importance of body position and its influence on stretch intensity, is largely unknown. In conclusion, this review has highlighted areas for future research, including stretch intensity and position and their effect on musculo-tendinous tissue, in relation to the sensation of pain, delayed onset muscle soreness, inflammation, as well as muscle health and performance. PMID:26347668

Acute effects of static and dynamic stretching on leg flexor and extensor isokinetic strength in elite women athletes.

PubMed

Sekir, U; Arabaci, R; Akova, B; Kadagan, S M

2010-04-01

The aim of this study was to explore the effects of static and dynamic stretching of the leg flexors and extensors on concentric and eccentric peak torque (PT) and electromyography (EMG) amplitude of the leg extensors and flexors in women athletes. Ten elite women athletes completed the following intervention protocol in a randomized order on separate days: (a) non-stretching (control), (b) static stretching, and (c) dynamic stretching. Stretched muscles were the quadriceps and hamstring muscles. Before and after the stretching or control intervention, concentric and eccentric isokinetic PT and EMG activity of the leg extensors and flexors were measured at 60 and 180 degrees/s. Concentric and eccentric quadriceps and hamstring muscle strength at both test speeds displayed a significant decrease following static stretching (P<0.01-0.001). In contrast, a significant increase was observed after dynamic stretching for these strength parameters (P<0.05-0.001). Parallel to this, normalized EMG amplitude parameters exhibited significant decreases following static (P<0.05-0.001) and significant increases following dynamic stretching (P<0.05-0.001) during quadriceps and hamstring muscle actions at both concentric and eccentric testing modes. Our findings suggest that dynamic stretching, as opposed to static or no stretching, may be an effective technique for enhancing muscle performance during the pre-competition warm-up routine in elite women athletes.

Comparison of the effects of local cryotherapy and passive cross-body stretch on extensibility in subjects with posterior shoulder tightness.

PubMed

Park, Kyue-Nam; Kwon, Oh-Yun; Weon, Jong-Hyuck; Choung, Sung-Dae; Kim, Si-Hyun

2014-01-01

The objective was to compare the immediate effects of local cryotherapy (LC) and passive cross-body stretch on the extensibility of the posterior shoulder muscle in individuals with posterior shoulder tightness. Eighty-seven healthy subjects with a between-shoulder difference in internal rotation (IR) range of motion (ROM) greater than 10° were randomly divided into three groups: LC group, stretching group, and control group (n = 29 in each group). Subjects in the LC group received LC on infraspinatus and posterior deltoid muscles and subjects in the stretching group performed passive cross-body stretch. Stretch sensation was measured at the end range of passive IR and horizontal adduction (HA) using numerical rating scale, and the pressure pain threshold (PPT) at the infraspinatus and posterior deltoid muscles was measured using pressure algometry. Passive and active ROM of IR and HA of the glenohumeral joint were measured using an inclinometer. All measurements were performed at pre-intervention, post- intervention, and 10-min follow-up. Stretch sensation was significantly decreased and PPT was significantly increased in the LC and stretching groups at post-intervention, and these effects were maintained at 10-min follow-up, compared to the control group. Both the LC group and stretching group had a significantly greater increase in passive and active ROM of IR and HA, compared to the control group at post-intervention and 10-min follow-up. However, there were no significant differences in stretch sensation, PPT, or ROM of IR and HA between the LC group and stretching group. LC can be used to decrease the stretch sensation and increase PPT and ROM of IR and HA as much as a stretching exercise. LC could be an alternative method for increasing the restricted ROM of glenohumeral IR and HA for individuals with posterior shoulder tightness, especially for patients and sports players who have severe stretching discomfort. Key PointsLocal cryotherapy (LC) decreased the uncomfortable stretch sensation, and increased the pressure pain threshold (PPT) of infraspinatus and posterior deltoid muscles in subjects with posterior shoulder tightness.Decreased stretch sensation by LC without passive stretching could improve the passive and active ROM of internal rotation and horizontal adduction in subjects with posterior shoulder tightness, similar to cross-body stretch.LC can be an alternative method to increase extensibility when individuals with posterior shoulder tightness have high stretch sensitivity and low PPT in the infraspinatus and posterior deltoid muscles.

Comparison of the Effects of Local Cryotherapy and Passive Cross-Body Stretch on Extensibility in Subjects with Posterior Shoulder Tightness

PubMed Central

Park, Kyue-nam; Kwon, Oh-yun; Weon, Jong-hyuck; Choung, Sung-dae; Kim, Si-hyun

2014-01-01

The objective was to compare the immediate effects of local cryotherapy (LC) and passive cross-body stretch on the extensibility of the posterior shoulder muscle in individuals with posterior shoulder tightness. Eighty-seven healthy subjects with a between-shoulder difference in internal rotation (IR) range of motion (ROM) greater than 10° were randomly divided into three groups: LC group, stretching group, and control group (n = 29 in each group). Subjects in the LC group received LC on infraspinatus and posterior deltoid muscles and subjects in the stretching group performed passive cross-body stretch. Stretch sensation was measured at the end range of passive IR and horizontal adduction (HA) using numerical rating scale, and the pressure pain threshold (PPT) at the infraspinatus and posterior deltoid muscles was measured using pressure algometry. Passive and active ROM of IR and HA of the glenohumeral joint were measured using an inclinometer. All measurements were performed at pre-intervention, post- intervention, and 10-min follow-up. Stretch sensation was significantly decreased and PPT was significantly increased in the LC and stretching groups at post-intervention, and these effects were maintained at 10-min follow-up, compared to the control group. Both the LC group and stretching group had a significantly greater increase in passive and active ROM of IR and HA, compared to the control group at post-intervention and 10-min follow-up. However, there were no significant differences in stretch sensation, PPT, or ROM of IR and HA between the LC group and stretching group. LC can be used to decrease the stretch sensation and increase PPT and ROM of IR and HA as much as a stretching exercise. LC could be an alternative method for increasing the restricted ROM of glenohumeral IR and HA for individuals with posterior shoulder tightness, especially for patients and sports players who have severe stretching discomfort. Key Points Local cryotherapy (LC) decreased the uncomfortable stretch sensation, and increased the pressure pain threshold (PPT) of infraspinatus and posterior deltoid muscles in subjects with posterior shoulder tightness. Decreased stretch sensation by LC without passive stretching could improve the passive and active ROM of internal rotation and horizontal adduction in subjects with posterior shoulder tightness, similar to cross-body stretch. LC can be an alternative method to increase extensibility when individuals with posterior shoulder tightness have high stretch sensitivity and low PPT in the infraspinatus and posterior deltoid muscles. PMID:24570610

Stretch marks

MedlinePlus

Stretch marks can appear when there is rapid stretching of the skin. The marks appear as parallel ... often disappear after the cause of the skin stretching is gone. Avoiding rapid weight gain helps reduce ...

Improved parameterization for the vertical flux of dust aerosols emitted by an eroding soil

USDA-ARS?s Scientific Manuscript database

The representation of the dust cycle in atmospheric circulation models hinges on an accurate parameterization of the vertical dust flux at emission. However, existing parameterizations of the vertical dust flux vary substantially in their scaling with wind friction velocity, require input parameters...

Climate and the equilibrium state of land surface hydrology parameterizations

NASA Technical Reports Server (NTRS)

Entekhabi, Dara; Eagleson, Peter S.

1991-01-01

For given climatic rates of precipitation and potential evaporation, the land surface hydrology parameterizations of atmospheric general circulation models will maintain soil-water storage conditions that balance the moisture input and output. The surface relative soil saturation for such climatic conditions serves as a measure of the land surface parameterization state under a given forcing. The equilibrium value of this variable for alternate parameterizations of land surface hydrology are determined as a function of climate and the sensitivity of the surface to shifts and changes in climatic forcing are estimated.

Cross-Section Parameterizations for Pion and Nucleon Production From Negative Pion-Proton Collisions

NASA Technical Reports Server (NTRS)

Norbury, John W.; Blattnig, Steve R.; Norman, Ryan; Tripathi, R. K.

2002-01-01

Ranft has provided parameterizations of Lorentz invariant differential cross sections for pion and nucleon production in pion-proton collisions that are compared to some recent data. The Ranft parameterizations are then numerically integrated to form spectral and total cross sections. These numerical integrations are further parameterized to provide formula for spectral and total cross sections suitable for use in radiation transport codes. The reactions analyzed are for charged pions in the initial state and both charged and neutral pions in the final state.

Anisotropic Shear Dispersion Parameterization for Mesoscale Eddy Transport

NASA Astrophysics Data System (ADS)

Reckinger, S. J.; Fox-Kemper, B.

2016-02-01

The effects of mesoscale eddies are universally treated isotropically in general circulation models. However, the processes that the parameterization approximates, such as shear dispersion, typically have strongly anisotropic characteristics. The Gent-McWilliams/Redi mesoscale eddy parameterization is extended for anisotropy and tested using 1-degree Community Earth System Model (CESM) simulations. The sensitivity of the model to anisotropy includes a reduction of temperature and salinity biases, a deepening of the southern ocean mixed-layer depth, and improved ventilation of biogeochemical tracers, particularly in oxygen minimum zones. The parameterization is further extended to include the effects of unresolved shear dispersion, which sets the strength and direction of anisotropy. The shear dispersion parameterization is similar to drifter observations in spatial distribution of diffusivity and high-resolution model diagnosis in the distribution of eddy flux orientation.

Controllers, observers, and applications thereof

NASA Technical Reports Server (NTRS)

Gao, Zhiqiang (Inventor); Zhou, Wankun (Inventor); Miklosovic, Robert (Inventor); Radke, Aaron (Inventor); Zheng, Qing (Inventor)

2011-01-01

Controller scaling and parameterization are described. Techniques that can be improved by employing the scaling and parameterization include, but are not limited to, controller design, tuning and optimization. The scaling and parameterization methods described here apply to transfer function based controllers, including PID controllers. The parameterization methods also apply to state feedback and state observer based controllers, as well as linear active disturbance rejection (ADRC) controllers. Parameterization simplifies the use of ADRC. A discrete extended state observer (DESO) and a generalized extended state observer (GESO) are described. They improve the performance of the ESO and therefore ADRC. A tracking control algorithm is also described that improves the performance of the ADRC controller. A general algorithm is described for applying ADRC to multi-input multi-output systems. Several specific applications of the control systems and processes are disclosed.

Balancing accuracy, efficiency, and flexibility in a radiative transfer parameterization for dynamical models

NASA Astrophysics Data System (ADS)

Pincus, R.; Mlawer, E. J.

2017-12-01

Radiation is key process in numerical models of the atmosphere. The problem is well-understood and the parameterization of radiation has seen relatively few conceptual advances in the past 15 years. It is nonthelss often the single most expensive component of all physical parameterizations despite being computed less frequently than other terms. This combination of cost and maturity suggests value in a single radiation parameterization that could be shared across models; devoting effort to a single parameterization might allow for fine tuning for efficiency. The challenge lies in the coupling of this parameterization to many disparate representations of clouds and aerosols. This talk will describe RRTMGP, a new radiation parameterization that seeks to balance efficiency and flexibility. This balance is struck by isolating computational tasks in "kernels" that expose as much fine-grained parallelism as possible. These have simple interfaces and are interoperable across programming languages so that they might be repalced by alternative implementations in domain-specific langauges. Coupling to the host model makes use of object-oriented features of Fortran 2003, minimizing branching within the kernels and the amount of data that must be transferred. We will show accuracy and efficiency results for a globally-representative set of atmospheric profiles using a relatively high-resolution spectral discretization.

Electronegativity Equalization Method: Parameterization and Validation for Large Sets of Organic, Organohalogene and Organometal Molecule

PubMed Central

Vařeková, Radka Svobodová; Jiroušková, Zuzana; Vaněk, Jakub; Suchomel, Šimon; Koča, Jaroslav

2007-01-01

The Electronegativity Equalization Method (EEM) is a fast approach for charge calculation. A challenging part of the EEM is the parameterization, which is performed using ab initio charges obtained for a set of molecules. The goal of our work was to perform the EEM parameterization for selected sets of organic, organohalogen and organometal molecules. We have performed the most robust parameterization published so far. The EEM parameterization was based on 12 training sets selected from a database of predicted 3D structures (NCI DIS) and from a database of crystallographic structures (CSD). Each set contained from 2000 to 6000 molecules. We have shown that the number of molecules in the training set is very important for quality of the parameters. We have improved EEM parameters (STO-3G MPA charges) for elements that were already parameterized, specifically: C, O, N, H, S, F and Cl. The new parameters provide more accurate charges than those published previously. We have also developed new parameters for elements that were not parameterized yet, specifically for Br, I, Fe and Zn. We have also performed crossover validation of all obtained parameters using all training sets that included relevant elements and confirmed that calculated parameters provide accurate charges.

Spectral cumulus parameterization based on cloud-resolving model

NASA Astrophysics Data System (ADS)

Baba, Yuya

2018-02-01

We have developed a spectral cumulus parameterization using a cloud-resolving model. This includes a new parameterization of the entrainment rate which was derived from analysis of the cloud properties obtained from the cloud-resolving model simulation and was valid for both shallow and deep convection. The new scheme was examined in a single-column model experiment and compared with the existing parameterization of Gregory (2001, Q J R Meteorol Soc 127:53-72) (GR scheme). The results showed that the GR scheme simulated more shallow and diluted convection than the new scheme. To further validate the physical performance of the parameterizations, Atmospheric Model Intercomparison Project (AMIP) experiments were performed, and the results were compared with reanalysis data. The new scheme performed better than the GR scheme in terms of mean state and variability of atmospheric circulation, i.e., the new scheme improved positive bias of precipitation in western Pacific region, and improved positive bias of outgoing shortwave radiation over the ocean. The new scheme also simulated better features of convectively coupled equatorial waves and Madden-Julian oscillation. These improvements were found to be derived from the modification of parameterization for the entrainment rate, i.e., the proposed parameterization suppressed excessive increase of entrainment, thus suppressing excessive increase of low-level clouds.

Effectiveness of a Load-Imposing Device for Cyclic Stretching of Isolated Human Bronchi: A Validation Study

PubMed Central

Le Guen, Morgan; Naline, Emmanuel; Grassin-Delyle, Stanislas; Devillier, Philippe; Faisy, Christophe

2015-01-01

Background Mechanical ventilation may induce harmful effects in the airways of critically ill patients. Nevertheless, the effects of cyclic stretching caused by repetitive inflation-deflation of the bronchial compartment have not been well characterized in humans. The objective of the present study was to assess the effectiveness of a load-imposing device for the cyclic stretching of human bronchi. Methods Intact bronchial segments were removed from 128 thoracic surgery patients. After preparation and equilibration in an organ bath, bronchi were stretched repetitively and cyclically with a motorized transducer. The peak force imposed on the bronchi was set to 80% of each individual maximum contraction in response to acetylcholine and the minimal force corresponded to the initial basal tone before stretching. A 1-min cycle (stretching for 15 sec, relaxing for 15 sec and resting for 30 sec) was applied over a time period ranging from 5 to 60 min. The device's performance level was assessed and the properties of the stretched bronchi were compared with those of paired, non-stretched bronchi. Results Despite the intrinsic capacities of the device, the targets of the tension adjustments remained variable for minimal tension (156–178%) while the peak force set point was unchanged (87–115%). In the stretched bronchi, a time-dependent rise in basal tone (P <.05 vs. non-stretched) was apparent after as little as 5 min of cyclic stretching. The stretch-induced rise in basal tone continued to increase (P <.01) after the stretching had ended. Only 60 min of cyclic stretching was associated with a significant (P <.05) increase in responsiveness to acetylcholine, relative to non-stretched bronchi. Conclusions Low-frequency, low-force, cyclic loading of human bronchi is associated with elevated basal tone and acetylcholine responsiveness. The present experimental model is likely to be a useful tool for future investigations of the bronchial response to repetitive stress during mechanical ventilation. PMID:26011598

Intermittent But Not Continuous Static Stretching Improves Subsequent Vertical Jump Performance In Flexibility-Trained Athletes.

PubMed

Bogdanis, Gregory C; Donti, Olyvia; Tsolakis, Charilaos; Smilios, Ilias; Bishop, David J

2017-02-23

This study examined changes in countermovement jump (CMJ) height after an intermittent or a continuous static stretching protocol of equal total duration. Sixteen male, elite-level gymnasts performed 90 s of intermittent (3 x 30 s with 30 s rest) or continuous stretching (90 s) of the quadriceps muscle. A single-leg stretching and jumping design was used, with the contra-lateral limb serving as a control. The same individuals performed both conditions with alternate legs in a randomized, counterbalanced order. One leg CMJ height was measured for the stretched and the control leg after warm-up, immediately after stretching, and at regular intervals for 10 min after stretching. Range of motion (ROM) of the hip and knee joints was measured before, after, and 10 min post-stretching. Compared to the control leg, intermittent stretching increased CMJ height by 8.1±2.0%, 4 min into recovery (+2.2±2.0 cm, 95%CI: 1.0-3.4 cm, p=0.001), while continuous stretching decreased CMJ height by 17.5±3.3% immediately after (-2.9±1.7 cm, 95%CI: -2.0 to -3.7 cm, p=0.001) and by 12.0±2.7% one min after stretching (-2.2±2.1 cm, 95%CI: -1.2 to -3.2 cm, p=0.001). The increases in hip (2.9 and 3.6, p=0.001. d=2.4) and knee joint ROM (5.1 and 6.1, p=0.001. d=0.85) after the intermittent and continuous stretching protocols were not different. The opposite effects of intermittent vs. continuous stretching on subsequent CMJ performance suggests that stretching mode is an important variable when examining the acute effects of static stretching on performance in flexibility-trained athletes.

Lamellar Thickness and Stretching Temperature Dependency of Cavitation in Semicrystalline Polymers

PubMed Central

Wang, Yaotao; Jiang, Zhiyong; Fu, Lianlian; Lu, Ying; Men, Yongfeng

2014-01-01

Polybutene-1 (PB-1), a typical semicrystalline polymer, in its stable form I shows a peculiar temperature dependent strain-whitening behavior when being stretched at temperatures in between room temperature and melting temperature of the crystallites where the extent of strain-whitening weakens with the increasing of stretching temperature reaching a minima value followed by an increase at higher stretching temperatures. Correspondingly, a stronger strain-hardening phenomenon was observed at higher temperatures. The strain-whitening phenomenon in semicrystalline polymers has its origin of cavitation process during stretching. In this work, the effect of crystalline lamellar thickness and stretching temperature on the cavitation process in PB-1 has been investigated by means of combined synchrotron ultrasmall-angle and wide-angle X-ray scattering techniques. Three modes of cavitation during the stretching process can be identified, namely “no cavitation” for the quenched sample with the thinnest lamellae where only shear yielding occurred, “cavitation with reorientation” for the samples stretched at lower temperatures and samples with thicker lamellae, and “cavitation without reorientation” for samples with thinner lamellae stretched at higher temperatures. The mode “cavitation with reorientation” occurs before yield point where the plate-like cavities start to be generated within the lamellar stacks with normal perpendicular to the stretching direction due to the blocky substructure of the crystalline lamellae and reorient gradually to the stretching direction after strain-hardening. The mode of “cavitation without reorientation” appears after yield point where ellipsoidal shaped cavities are generated in those lamellae stacks with normal parallel to the stretching direction followed by an improvement of their orientation at larger strains. X-ray diffraction results reveal a much improved crystalline orientation for samples with thinner lamellae stretched at higher temperatures. The observed behavior of microscopic structural evolution in PB-1 stretched at different temperatures explains above mentioned changes in macroscopic strain-whitening phenomenon with increasing in stretching temperature and stress-strain curves. PMID:24820772

Acute effects of warm-up stretch protocols on balance, vertical jump height, and range of motion in dancers.

PubMed

Morrin, Niamh; Redding, Emma

2013-01-01

The aim of this study was to examine the acute effects of static stretching (SS), dynamic stretching (DS), and a combined (static and dynamic) stretch protocol on vertical jump (VJ) height, balance, and range of motion (ROM) in dancers. A no-stretch (NS) intervention acted as the control condition. It was hypothesized that the DS and combination stretch protocols would have more positive effects on performance indicators than SS and NS, and SS would have negative effects as compared to the NS condition. Ten trained female dancers (27 ± 5 years of age) were tested on four occasions. Each session began with initial measurements of hamstring ROM on the dominant leg. The participants subsequently carried out a cardiovascular (CV) warm-up, which was followed by one of the four randomly selected stretch conditions. Immediately after the stretch intervention the participants were tested on VJ performance, hamstring ROM, and balance. The data showed that DS (p < 0.05) and the combination stretch (p < .05) produced significantly greater VJ height scores as compared to SS, and the combination stretch demonstrated significantly enhanced balance performance as compared to SS (p < 0.05). With regard to ROM, a one-way ANOVA indicated that SS and the combination stretch displayed significantly greater changes in ROM than DS (p < 0.05). From comparison of the stretch protocols used in the current study, it can be concluded that SS does not appear to be detrimental to a dancer's performance, and DS has some benefits but not in all three key area's tested, namely lower body power (VJ height), balance, and range of motion. However, combination stretching showed significantly enhanced balance and vertical jump height scores and significantly improved pre-stretch and post-stretch ROM values. It is therefore suggested that a combined warm-up protocol consisting of SS and DS should be promoted as an effective warm-up for dancers.

Manipulation of sensory input can improve stretching outcomes.

PubMed

Capobianco, Robyn A; Almuklass, Awad M; Enoka, Roger M

2018-02-01

The primary purpose of our study was to assess the influence of modulating sensory input with either transcutaneous electrical nerve stimulation (TENS) or self-massage with therapy balls on the maximal range of motion (ROM) about the ankle joint when stretching the calf muscles. We also investigated the influence of these two conditions on the force capacity and force control of plantar flexor muscles. Twenty healthy adults (25 ± 3 yr) performed three sessions of ankle plantar flexor stretching (three stretches of 30 s each): stretching alone (SS), stretching with concurrent TENS (TENS), and stretching after self-massage using therapy balls (SM). TENS was applied for 60 s prior to and during each stretch, and SM was performed for 60 s prior to each of the three stretches. Maximal voluntary contraction (MVC) torque and force steadiness at 20% MVC were recorded before and at 15 min after the final stretch. Ankle dorsiflexion ROM was assessed before, after, and at 5, 10, and 15 min after the last stretch. The increase in ROM was greater after SM (24%) than after SS (13%) and TENS (9%; p < .001). Maximal discomfort level (0-10 VAS) during stretching was similar for all conditions. MVC torque increased after SM only (p < .001, Cohen's D = 1.5): SM, 16%; SS, -1%; TENS, -3%. Force steadiness did not change. The sensory fibres that contribute to stretch tolerance were engaged by self-massage but not by TENS, resulting in greater increases in flexibility and MVC torque after self-massage.

Universal entanglement timescale for Rényi entropies

NASA Astrophysics Data System (ADS)

Cresswell, Jesse C.

2018-02-01

Recently it was shown that the growth of entanglement in an initially separable state, as measured by the purity of subsystems, can be characterized by a timescale that takes a universal form for any Hamiltonian. We show that the same timescale governs the growth of entanglement for all Rényi entropies. Since the family of Rényi entropies completely characterizes the entanglement of a pure bipartite state, our timescale is a universal feature of bipartite entanglement. The timescale depends only on the interaction Hamiltonian and the initial state.

The combined effects of transcutaneous electrical nerve stimulation (TENS) and stretching on muscle hardness and pressure pain threshold.

PubMed

Karasuno, Hiroshi; Ogihara, Hisayoshi; Morishita, Katsuyuki; Yokoi, Yuka; Fujiwara, Takayuki; Ogoma, Yoshiro; Abe, Koji

2016-04-01

[Purpose] This study aimed to clarify the immediate effects of a combined transcutaneous electrical nerve stimulation and stretching protocol. [Subjects] Fifteen healthy young males volunteered to participate in this study. The inclusion criterion was a straight leg raising range of motion of less than 70 degrees. [Methods] Subjects performed two protocols: 1) stretching (S group) of the medial hamstrings, and 2) tanscutaneous electrical nerve stimulation (100 Hz) with stretching (TS group). The TS group included a 20-minute electrical stimulation period followed by 10 minutes of stretching. The S group performed 10 minutes of stretching. Muscle hardness, pressure pain threshold, and straight leg raising range of motion were analyzed to evaluate the effects. The data were collected before transcutaneous electrical nerve stimulation (T1), before stretching (T2), immediately after stretching (T3), and 10 minutes after stretching (T4). [Results] Combined transcutaneous electrical nerve stimulation and stretching had significantly beneficial effects on muscle hardness, pressure pain threshold, and straight leg raising range of motion at T2, T3, and T4 compared with T1. [Conclusion] These results support the belief that transcutaneous electrical nerve stimulation combined with stretching is effective in reducing pain and decreasing muscle hardness, thus increasing range of motion.

Frequency and peak stretch magnitude affect alveolar epithelial permeability.

PubMed

Cohen, T S; Cavanaugh, K J; Margulies, S S

2008-10-01

The present study measured stretch-induced changes in transepithelial permeability to uncharged tracers (1.5-5.5 A) using cultured monolayers of alveolar epithelial type-I like cells. Cultured alveolar epithelial cells were subjected to uniform cyclic (0, 0.25 and 1.0 Hz) biaxial stretch from 0% to 12, 25 or 37% change in surface area (DeltaSA) for 1 h. Significant changes in permeability of cell monolayers were observed when stretched from 0% to 37% DeltaSA at all frequencies, and from 0% to 25% DeltaSA only at high frequency (1 Hz), but not at all when stretched from 0% to 12% DeltaSA compared with unstretched controls. At stretch oscillation amplitudes of 25 and 37% DeltaSA, imposed at 1 Hz, tracer permeability increased compared with that at 0.25 Hz. Cells subjected to a single stretch cycle at 37% DeltaSA (0.25 Hz), to simulate a deep sigh, were not distinguishable from unstretched controls. Reducing stretch oscillation amplitude while maintaining a peak stretch of 37% DeltaSA (0.25 Hz) via the application of a simulated post-end-expiratory pressure did not protect barrier properties. In conclusion, peak stretch magnitude and stretch frequency were the primary determining factors for epithelial barrier dysfunction, as opposed to oscillation amplitude.

Evaluate transport processes in MERRA driven chemical transport models using updated 222Rn emission inventories and global observations

NASA Astrophysics Data System (ADS)

Zhang, B.; Liu, H.; Crawford, J. H.; Fairlie, T. D.; Chen, G.; Chambers, S. D.; Kang, C. H.; Williams, A. G.; Zhang, K.; Considine, D. B.; Payer Sulprizio, M.; Yantosca, R.

2015-12-01

Convective and synoptic processes play a major role in determining the transport and distribution of trace gases and aerosols in the troposphere. The representation of these processes in global models (at ~100-1000 km horizontal resolution) is challenging, because convection is a sub-grid process and needs to be parameterized, while synoptic processes are close to the grid scale. Depending on the parameterization schemes used in climate models, the role of convection in transporting trace gases and aerosols may vary from model to model. 222Rn is a chemically inert and radioactive gas constantly emitted from soil and has a half-life (3.8 days) comparable to synoptic timescale, which makes it an effective tracer for convective and synoptic transport. In this study, we evaluate the convective and synoptic transport in two chemical transport models (GMI and GEOS-Chem), both driven by the NASA's MERRA reanalysis. Considering the uncertainties in 222Rn emissions, we incorporate two more recent scenarios with regionally varying 222Rn emissions into GEOS-Chem/MERRA and compare the simulation results with those using the relatively uniform 222Rn emissions in the standard model. We evaluate the global distribution and seasonality of 222Rn concentrations simulated by the two models against an extended collection of 222Rn observations from 1970s to 2010s. The intercomparison will improve our understanding of the spatial variability in global 222Rn emissions, including the suspected excessive 222Rn emissions in East Asia, and provide useful feedbacks on 222Rn emission models. We will assess 222Rn vertical distributions at different latitudes in the models using observations at surface sites and in the upper troposphere and lower stratosphere. Results will be compared with previous models driven by other meteorological fields (e.g., fvGCM and GEOS4). Since the decay of 222Rn is the source of 210Pb, a useful radionuclide tracer attached to submicron aerosols, improved understanding of emissions and transport of 222Rn will provide insights into the transport, distribution, and wet deposition of 210Pb aerosols.

Oxygen uptake and vertical transport during deep convection events

NASA Astrophysics Data System (ADS)

Sun, D.; Ito, T.; Bracco, A.

2016-02-01

Dissolved oxygen (O2) is essential for the chemistry and living organisms of the oceans. O2 is consumed in the interior ocean due to the respiration of organic matter, and must be replenished by physical ventilation with the O2-rich surface waters. The O2 supply to the deep waters happens only through the subduction and deep convection during cold seasons at high latitude oceans. The Labrador Sea is one of the few regions where deep ventilation occurs. According to observational and modeling studies, the intensity, duration and timing of deep convection events have varied significantly on the interannual and decadal timescales. In this study we develop a theoretical framework to understand the air-sea transfer of O2 during open-ocean deep convection events. The theory is tested against a suite of numerical integrations using MITgcm in non-hydrostatic configuration including the parameterization of diffusive and bubble mediated gas transfer. Forced with realistic air-sea buoyancy fluxes, the model can reproduce the evolution of temperature, salinity and dissolved O2 observed by ARGO floats in the Labrador Sea. Idealized sensitivity experiments are performed changing the intensity and duration of the buoyancy forcing as well as the wind speed for the gas exchange parameterizations. The downward transport of O2 results from the combination of vertical homogenization of existing O2 and the uptake from the air-sea flux. The intensity of the buoyancy forcing controls the vertical extent of convective mixing which brings O2 to the deep ocean. Integrated O2 uptake increases with the duration of convection even when the total buoyancy loss is held constant. The air-sea fluxes are highly sensitive to the wind speed especially for the bubble injection flux, which is a major addition to the diffusive flux under strong winds. However, the bubble injection flux can be partially compensated by the diffusive outgassing in response to the elevated saturation state. Under strong buoyancy forcing, this compensation is suppressed by the entrainment of relatively O2-poor deep waters. These results imply and allow to quantify the direct link between variability of deep convection and the supply of O2 in the North Atlantic.

Simulation of charge transfer and orbital rehybridization in molecular and condensed matter systems

NASA Astrophysics Data System (ADS)

Nistor, Razvan A.

The mixing and shifting of electronic orbitals in molecules, or between atoms in bulk systems, is crucially important to the overall structure and physical properties of materials. Understanding and accurately modeling these orbital interactions is of both scientific and industrial relevance. Electronic orbitals can be perturbed in several ways. Doping, adding or removing electrons from systems, can change the bond-order and the physical properties of certain materials. Orbital rehybridization, driven by either thermal or pressure excitation, alters the short-range structure of materials and changes their long-range transport properties. Macroscopically, during bond formation, the shifting of electronic orbitals can be interpreted as a charge transfer phenomenon, as electron density may pile up around, and hence, alter the effective charge of, a given atom in the changing chemical environment. Several levels of theory exist to elucidate the mechanisms behind these orbital interactions. Electronic structure calculations solve the time-independent Schrodinger equation to high chemical accuracy, but are computationally expensive and limited to small system sizes and simulation times. Less fundamental atomistic calculations use simpler parameterized functional expressions called force-fields to model atomic interactions. Atomistic simulations can describe systems and time-scales larger and longer than electronic-structure methods, but at the cost of chemical accuracy. In this thesis, both first-principles and phenomenological methods are addressed in the study of several encompassing problems dealing with charge transfer and orbital rehybridization. Firstly, a new charge-equilibration method is developed that improves upon existing models to allow next-generation force-fields to describe the electrostatics of changing chemical environments. Secondly, electronic structure calculations are used to investigate the doping dependent energy landscapes of several high-temperature superconducting materials in order to parameterize the apparently large nonlinear electron-phonon coupling. Thirdly, ab initio simulations are used to investigate the role of pressure-driven structural re-organization in the crystalline-to-amorphous (or, metallic-to-insulating) transition of a common binary phase-change material composed of Ge and Sb. Practical applications of each topic will be discussed. Keywords. Charge-equilibration methods, molecular dynamics, electronic structure calculations, ab initio simulations, high-temperature superconductors, phase-change materials.

Stretching Safely and Effectively

MedlinePlus

... shown that stretching immediately before an event weakens hamstring strength. Instead of static stretching, try performing a " ... If you play soccer, for instance, stretch your hamstrings as you're more vulnerable to hamstring strains. ...

Daily muscle stretching enhances blood flow, endothelial function, capillarity, vascular volume and connectivity in aged skeletal muscle.

PubMed

Hotta, Kazuki; Behnke, Bradley J; Arjmandi, Bahram; Ghosh, Payal; Chen, Bei; Brooks, Rachael; Maraj, Joshua J; Elam, Marcus L; Maher, Patrick; Kurien, Daniel; Churchill, Alexandra; Sepulveda, Jaime L; Kabolowsky, Max B; Christou, Demetra D; Muller-Delp, Judy M

2018-05-15

In aged rats, daily muscle stretching increases blood flow to skeletal muscle during exercise. Daily muscle stretching enhanced endothelium-dependent vasodilatation of skeletal muscle resistance arterioles of aged rats. Angiogenic markers and capillarity increased in response to daily stretching in muscles of aged rats. Muscle stretching performed with a splint could provide a feasible means of improving muscle blood flow and function in elderly patients who cannot perform regular aerobic exercise. Mechanical stretch stimuli alter the morphology and function of cultured endothelial cells; however, little is known about the effects of daily muscle stretching on adaptations of endothelial function and muscle blood flow. The present study aimed to determine the effects of daily muscle stretching on endothelium-dependent vasodilatation and muscle blood flow in aged rats. The lower hindlimb muscles of aged Fischer rats were passively stretched by placing an ankle dorsiflexion splint for 30 min day -1 , 5 days week -1 , for 4 weeks. Blood flow to the stretched limb and the non-stretched contralateral limb was determined at rest and during treadmill exercise. Endothelium-dependent/independent vasodilatation was evaluated in soleus muscle arterioles. Levels of hypoxia-induced factor-1α, vascular endothelial growth factor A and neuronal nitric oxide synthase were determined in soleus muscle fibres. Levels of endothelial nitric oxide synthase and superoxide dismutase were determined in soleus muscle arterioles, and microvascular volume and capillarity were evaluated by microcomputed tomography and lectin staining, respectively. During exercise, blood flow to plantar flexor muscles was significantly higher in the stretched limb. Endothelium-dependent vasodilatation was enhanced in arterioles from the soleus muscle from the stretched limb. Microvascular volume, number of capillaries per muscle fibre, and levels of hypoxia-induced factor-1α, vascular endothelial growth factor and endothelial nitric oxide synthase were significantly higher in the stretched limb. These results indicate that daily passive stretching of muscle enhances endothelium-dependent vasodilatation and induces angiogenesis. These microvascular adaptations may contribute to increased muscle blood flow during exercise in muscles that have undergone daily passive stretch. © 2018 The Authors. The Journal of Physiology © 2018 The Physiological Society.

Unilateral Plantar Flexors Static-Stretching Effects on Ipsilateral and Contralateral Jump Measures

PubMed Central

da Silva, Josinaldo Jarbas; Behm, David George; Gomes, Willy Andrade; Silva, Fernando Henrique Domingues de Oliveira; Soares, Enrico Gori; Serpa, Érica Paes; Vilela Junior, Guanis de Barros; Lopes, Charles Ricardo; Marchetti, Paulo Henrique

2015-01-01

The aim of this study was to evaluate the acute effects of unilateral ankle plantar flexors static-stretching (SS) on the passive range of movement (ROM) of the stretched limb, surface electromyography (sEMG) and single-leg bounce drop jump (SBDJ) performance measures of the ipsilateral stretched and contralateral non-stretched lower limbs. Seventeen young men (24 ± 5 years) performed SBDJ before and after (stretched limb: immediately post-stretch, 10 and 20 minutes and non-stretched limb: immediately post-stretch) unilateral ankle plantar flexor SS (6 sets of 45s/15s, 70-90% point of discomfort). SBDJ performance measures included jump height, impulse, time to reach peak force, contact time as well as the sEMG integral (IEMG) and pre-activation (IEMGpre-activation) of the gastrocnemius lateralis. Ankle dorsiflexion passive ROM increased in the stretched limb after the SS (pre-test: 21 ± 4° and post-test: 26.5 ± 5°, p < 0.001). Post-stretching decreases were observed with peak force (p = 0.029), IEMG (P<0.001), and IEMGpre-activation (p = 0.015) in the stretched limb; as well as impulse (p = 0.03), and jump height (p = 0.032) in the non-stretched limb. In conclusion, SS effectively increased passive ankle ROM of the stretched limb, and transiently (less than 10 minutes) decreased muscle peak force and pre-activation. The decrease of jump height and impulse for the non-stretched limb suggests a SS-induced central nervous system inhibitory effect. Key points When considering whether or not to SS prior to athletic activities, one must consider the potential positive effects of increased ankle dorsiflexion motion with the potential deleterious effects of power and muscle activity during a simple jumping task or as part of the rehabilitation process. Since decreased jump performance measures can persist for 10 minutes in the stretched leg, the timing of SS prior to performance must be taken into consideration. Athletes, fitness enthusiasts and therapists should also keep in mind that SS one limb has generalized effects upon contralateral limbs as well. PMID:25983580

Forced-Unfolding and Force-Quench Refolding of RNA Hairpins

PubMed Central

Hyeon, Changbong; Thirumalai, D.

2006-01-01

Nanomanipulation of individual RNA molecules, using laser optical tweezers, has made it possible to infer the major features of their energy landscape. Time-dependent mechanical unfolding trajectories, measured at a constant stretching force (fS) of simple RNA structures (hairpins and three-helix junctions) sandwiched between RNA/DNA hybrid handles show that they unfold in a reversible all-or-none manner. To provide a molecular interpretation of the experiments we use a general coarse-grained off-lattice Gō-like model, in which each nucleotide is represented using three interaction sites. Using the coarse-grained model we have explored forced-unfolding of RNA hairpin as a function of fS and the loading rate (rf). The simulations and theoretical analysis have been done both with and without the handles that are explicitly modeled by semiflexible polymer chains. The mechanisms and timescales for denaturation by temperature jump and mechanical unfolding are vastly different. The directed perturbation of the native state by fS results in a sequential unfolding of the hairpin starting from their ends, whereas thermal denaturation occurs stochastically. From the dependence of the unfolding rates on rf and fS we show that the position of the unfolding transition state is not a constant but moves dramatically as either rf or fS is changed. The transition-state movements are interpreted by adopting the Hammond postulate for forced-unfolding. Forced-unfolding simulations of RNA, with handles attached to the two ends, show that the value of the unfolding force increases (especially at high pulling speeds) as the length of the handles increases. The pathways for refolding of RNA from stretched initial conformation, upon quenching fS to the quench force fQ, are highly heterogeneous. The refolding times, upon force-quench, are at least an order-of-magnitude greater than those obtained by temperature-quench. The long fQ-dependent refolding times starting from fully stretched states are analyzed using a model that accounts for the microscopic steps in the rate-limiting step, which involves the trans to gauche transitions of the dihedral angles in the GAAA tetraloop. The simulations with explicit molecular model for the handles show that the dynamics of force-quench refolding is strongly dependent on the interplay of their contour length and persistence length and the RNA persistence length. Using the generality of our results, we also make a number of precise experimentally testable predictions. PMID:16473903

50 CFR 697.7 - Prohibitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

...-inch (8.3 cm) square stretch mesh (as measured between the centers of opposite knots when stretched taut) or 33/4-inch (9.5 cm) diamond stretch mesh for trawls and 27/8-inch (7.3 cm) stretch mesh for..., in the EEZ when using a mesh size less than 3 1/4-inch (8.3 cm) square stretch mesh (as measured...

50 CFR 697.7 - Prohibitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

...-inch (8.3 cm) square stretch mesh (as measured between the centers of opposite knots when stretched taut) or 33/4-inch (9.5 cm) diamond stretch mesh for trawls and 27/8-inch (7.3 cm) stretch mesh for..., in the EEZ when using a mesh size less than 3 1/4-inch (8.3 cm) square stretch mesh (as measured...

50 CFR 697.7 - Prohibitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

...-inch (8.3 cm) square stretch mesh (as measured between the centers of opposite knots when stretched taut) or 33/4-inch (9.5 cm) diamond stretch mesh for trawls and 27/8-inch (7.3 cm) stretch mesh for..., in the EEZ when using a mesh size less than 3 1/4-inch (8.3 cm) square stretch mesh (as measured...

Fluidization, resolidification, and reorientation of the endothelial cell in response to slow tidal stretches

PubMed Central

Krishnan, Ramaswamy; Canović, Elizabeth Peruski; Iordan, Andreea L.; Rajendran, Kavitha; Manomohan, Greeshma; Pirentis, Athanassios P.; Smith, Michael L.; Butler, James P.; Fredberg, Jeffrey J.

2012-01-01

Mechanical stretch plays an important role in regulating shape and orientation of the vascular endothelial cell. This morphological response to stretch is basic to angiogenesis, neovascularization, and vascular homeostasis, but mechanism remains unclear. To elucidate mechanisms, we used cell mapping rheometry to measure traction forces in primary human umbilical vein endothelial cells subjected to periodic uniaxial stretches. Onset of periodic stretch of 10% strain amplitude caused a fluidization response typified by attenuation of traction forces almost to zero. As periodic stretch continued, the prompt fluidization response was followed by a slow resolidification response typified by recovery of the traction forces, but now aligned along the axis perpendicular to the imposed stretch. Reorientation of the cell body lagged reorientation of the traction forces, however. Together, these observations demonstrate that cellular reorientation in response to periodic stretch is preceded by traction attenuation by means of cytoskeletal fluidization and subsequent traction recovery transverse to the stretch direction by means of cytoskeletal resolidification. PMID:22700796

The importance of parameterization when simulating the hydrologic response of vegetative land-cover change

NASA Astrophysics Data System (ADS)

White, Jeremy; Stengel, Victoria; Rendon, Samuel; Banta, John

2017-08-01

Computer models of hydrologic systems are frequently used to investigate the hydrologic response of land-cover change. If the modeling results are used to inform resource-management decisions, then providing robust estimates of uncertainty in the simulated response is an important consideration. Here we examine the importance of parameterization, a necessarily subjective process, on uncertainty estimates of the simulated hydrologic response of land-cover change. Specifically, we applied the soil water assessment tool (SWAT) model to a 1.4 km2 watershed in southern Texas to investigate the simulated hydrologic response of brush management (the mechanical removal of woody plants), a discrete land-cover change. The watershed was instrumented before and after brush-management activities were undertaken, and estimates of precipitation, streamflow, and evapotranspiration (ET) are available; these data were used to condition and verify the model. The role of parameterization in brush-management simulation was evaluated by constructing two models, one with 12 adjustable parameters (reduced parameterization) and one with 1305 adjustable parameters (full parameterization). Both models were subjected to global sensitivity analysis as well as Monte Carlo and generalized likelihood uncertainty estimation (GLUE) conditioning to identify important model inputs and to estimate uncertainty in several quantities of interest related to brush management. Many realizations from both parameterizations were identified as behavioral in that they reproduce daily mean streamflow acceptably well according to Nash-Sutcliffe model efficiency coefficient, percent bias, and coefficient of determination. However, the total volumetric ET difference resulting from simulated brush management remains highly uncertain after conditioning to daily mean streamflow, indicating that streamflow data alone are not sufficient to inform the model inputs that influence the simulated outcomes of brush management the most. Additionally, the reduced-parameterization model grossly underestimates uncertainty in the total volumetric ET difference compared to the full-parameterization model; total volumetric ET difference is a primary metric for evaluating the outcomes of brush management. The failure of the reduced-parameterization model to provide robust uncertainty estimates demonstrates the importance of parameterization when attempting to quantify uncertainty in land-cover change simulations.

The importance of parameterization when simulating the hydrologic response of vegetative land-cover change

USGS Publications Warehouse

White, Jeremy; Stengel, Victoria G.; Rendon, Samuel H.; Banta, John

2017-01-01

Computer models of hydrologic systems are frequently used to investigate the hydrologic response of land-cover change. If the modeling results are used to inform resource-management decisions, then providing robust estimates of uncertainty in the simulated response is an important consideration. Here we examine the importance of parameterization, a necessarily subjective process, on uncertainty estimates of the simulated hydrologic response of land-cover change. Specifically, we applied the soil water assessment tool (SWAT) model to a 1.4 km2 watershed in southern Texas to investigate the simulated hydrologic response of brush management (the mechanical removal of woody plants), a discrete land-cover change. The watershed was instrumented before and after brush-management activities were undertaken, and estimates of precipitation, streamflow, and evapotranspiration (ET) are available; these data were used to condition and verify the model. The role of parameterization in brush-management simulation was evaluated by constructing two models, one with 12 adjustable parameters (reduced parameterization) and one with 1305 adjustable parameters (full parameterization). Both models were subjected to global sensitivity analysis as well as Monte Carlo and generalized likelihood uncertainty estimation (GLUE) conditioning to identify important model inputs and to estimate uncertainty in several quantities of interest related to brush management. Many realizations from both parameterizations were identified as behavioral in that they reproduce daily mean streamflow acceptably well according to Nash–Sutcliffe model efficiency coefficient, percent bias, and coefficient of determination. However, the total volumetric ET difference resulting from simulated brush management remains highly uncertain after conditioning to daily mean streamflow, indicating that streamflow data alone are not sufficient to inform the model inputs that influence the simulated outcomes of brush management the most. Additionally, the reduced-parameterization model grossly underestimates uncertainty in the total volumetric ET difference compared to the full-parameterization model; total volumetric ET difference is a primary metric for evaluating the outcomes of brush management. The failure of the reduced-parameterization model to provide robust uncertainty estimates demonstrates the importance of parameterization when attempting to quantify uncertainty in land-cover change simulations.

Adaptive dynamics on an environmental gradient that changes over a geological time-scale.

PubMed

Fortelius, Mikael; Geritz, Stefan; Gyllenberg, Mats; Toivonen, Jaakko

2015-07-07

The standard adaptive dynamics framework assumes two timescales, i.e. fast population dynamics and slow evolutionary dynamics. We further assume a third timescale, which is even slower than the evolutionary timescale. We call this the geological timescale and we assume that slow climatic change occurs within this timescale. We study the evolution of our model population over this very slow geological timescale with bifurcation plots of the standard adaptive dynamics framework. The bifurcation parameter being varied describes the abiotic environment that changes over the geological timescale. We construct evolutionary trees over the geological timescale and observe both gradual phenotypic evolution and punctuated branching events. We concur with the established notion that branching of a monomorphic population on an environmental gradient only happens when the gradient is not too shallow and not too steep. However, we show that evolution within the habitat can produce polymorphic populations that inhabit steep gradients. What is necessary is that the environmental gradient at some point in time is such that the initial branching of the monomorphic population can occur. We also find that phenotypes adapted to environments in the middle of the existing environmental range are more likely to branch than phenotypes adapted to extreme environments. Copyright © 2015 Elsevier Ltd. All rights reserved.

Experimental evidence for an optical interference model for vibrational sum frequency generation on multilayer organic thin film systems. I. Electric dipole approximation.

PubMed

O'Brien, Daniel B; Massari, Aaron M

2015-01-14

In the field of vibrational sum frequency generation spectroscopy (VSFG) applied to organic thin film systems, a significant challenge to data analysis is in the accurate description of optical interference effects. Herein, we provide experimental evidence that a model recently developed in our lab provides an accurate description of this phenomenon. We studied the organic small molecule N,N'-dioctyl-3,4,9,10-perylenedicarboximide vapor deposited as a thickness gradient on silicon wafer substrates with two oxide thicknesses and two surface preps. VSFG data were obtained using the ssp and the sps polarization combinations in the imide carbonyl stretching region as a function of organic thickness. In this first of two reports, the data are modeled and interpreted within the ubiquitous electric dipole approximation for VSFG. The intrinsic sample responses are parameterized during the fitting routines while optical interference effects are simply calculated from the model using known refractive indices, thin film thicknesses, and beam angles. The results indicate that the thin film model provides a good description of optical interferences, indicating that interfacial terms are significant. Inconsistencies between the fitting results within the bounds of the electric dipole response motivate deliberation for additional effects to be considered in the second report.

Coarse-Grained Models Reveal Functional Dynamics – II. Molecular Dynamics Simulation at the Coarse-Grained Level – Theories and Biological Applications

PubMed Central

Chng, Choon-Peng; Yang, Lee-Wei

2008-01-01

Molecular dynamics (MD) simulation has remained the most indispensable tool in studying equilibrium/non-equilibrium conformational dynamics since its advent 30 years ago. With advances in spectroscopy accompanying solved biocomplexes in growing sizes, sampling their dynamics that occur at biologically interesting spatial/temporal scales becomes computationally intractable; this motivated the use of coarse-grained (CG) approaches. CG-MD models are used to study folding and conformational transitions in reduced resolution and can employ enlarged time steps due to the absence of some of the fastest motions in the system. The Boltzmann-Inversion technique, heavily used in parameterizing these models, provides a smoothed-out effective potential on which molecular conformation evolves at a faster pace thus stretching simulations into tens of microseconds. As a result, a complete catalytic cycle of HIV-1 protease or the assembly of lipid-protein mixtures could be investigated by CG-MD to gain biological insights. In this review, we survey the theories developed in recent years, which are categorized into Folding-based and Molecular-Mechanics-based. In addition, physical bases in the selection of CG beads/time-step, the choice of effective potentials, representation of solvent, and restoration of molecular representations back to their atomic details are systematically discussed. PMID:19812774

A reassessment of the role of tidal dispersion in estuaries and bays

USGS Publications Warehouse

Geyer, W. Rockwell; Signell, Richard P.

1992-01-01

The role of tidal dispersion is reassessed, based on a consideration of the relevant physical mechanisms, particularly those elucidated by numerical simulations of tide-induced dispersion. It appears that the principal influence of tidal currents on dispersion occurs at length scales of the tidal excursion and smaller; thus the effectiveness of tidal dispersion depends on the relative scale of the tidal excursion to the spacing between major bathymetric and shoreline features. In estuaries where the typical spacing of topographic features is less than the tidal excursion, tidal dispersion may contribute significantly to the overall flushing. In estuaries and embayments in which the typical spacing between major features is larger than the tidal excursion, the influence of tidal dispersion will be localized, and it will not markedly contribute to overall flushing. Tidal dispersion is most pronounced in regions of abrupt topographic changes such as headlands and inlets, where flow separation occurs. The strong strain rate in the region of flow separation tends to stretch patches of fluid into long filaments, which are subsequently rolled up and distorted by the transient eddy field. The dispersion process accomplished by the tides varies strongly as a function of position and tidal phase and thus does not lend itself to parameterization by an eddy diffusion coefficient.

FINAL REPORT (DE-FG02-97ER62338): Single-column modeling, GCM parameterizations, and ARM data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Richard C. J. Somerville

2009-02-27

Our overall goal is the development of new and improved parameterizations of cloud-radiation effects and related processes, using ARM data at all three ARM sites, and the implementation and testing of these parameterizations in global models. To test recently developed prognostic parameterizations based on detailed cloud microphysics, we have compared SCM (single-column model) output with ARM observations at the SGP, NSA and TWP sites. We focus on the predicted cloud amounts and on a suite of radiative quantities strongly dependent on clouds, such as downwelling surface shortwave radiation. Our results demonstrate the superiority of parameterizations based on comprehensive treatments ofmore » cloud microphysics and cloud-radiative interactions. At the SGP and NSA sites, the SCM results simulate the ARM measurements well and are demonstrably more realistic than typical parameterizations found in conventional operational forecasting models. At the TWP site, the model performance depends strongly on details of the scheme, and the results of our diagnostic tests suggest ways to develop improved parameterizations better suited to simulating cloud-radiation interactions in the tropics generally. These advances have made it possible to take the next step and build on this progress, by incorporating our parameterization schemes in state-of-the-art three-dimensional atmospheric models, and diagnosing and evaluating the results using independent data. Because the improved cloud-radiation results have been obtained largely via implementing detailed and physically comprehensive cloud microphysics, we anticipate that improved predictions of hydrologic cycle components, and hence of precipitation, may also be achievable.« less

Parametric soil water retention models: a critical evaluation of expressions for the full moisture range

NASA Astrophysics Data System (ADS)

Madi, Raneem; Huibert de Rooij, Gerrit; Mielenz, Henrike; Mai, Juliane

2018-02-01

Few parametric expressions for the soil water retention curve are suitable for dry conditions. Furthermore, expressions for the soil hydraulic conductivity curves associated with parametric retention functions can behave unrealistically near saturation. We developed a general criterion for water retention parameterizations that ensures physically plausible conductivity curves. Only 3 of the 18 tested parameterizations met this criterion without restrictions on the parameters of a popular conductivity curve parameterization. A fourth required one parameter to be fixed. We estimated parameters by shuffled complex evolution (SCE) with the objective function tailored to various observation methods used to obtain retention curve data. We fitted the four parameterizations with physically plausible conductivities as well as the most widely used parameterization. The performance of the resulting 12 combinations of retention and conductivity curves was assessed in a numerical study with 751 days of semiarid atmospheric forcing applied to unvegetated, uniform, 1 m freely draining columns for four textures. Choosing different parameterizations had a minor effect on evaporation, but cumulative bottom fluxes varied by up to an order of magnitude between them. This highlights the need for a careful selection of the soil hydraulic parameterization that ideally does not only rely on goodness of fit to static soil water retention data but also on hydraulic conductivity measurements. Parameter fits for 21 soils showed that extrapolations into the dry range of the retention curve often became physically more realistic when the parameterization had a logarithmic dry branch, particularly in fine-textured soils where high residual water contents would otherwise be fitted.

How certain are the process parameterizations in our models?

NASA Astrophysics Data System (ADS)

Gharari, Shervan; Hrachowitz, Markus; Fenicia, Fabrizio; Matgen, Patrick; Razavi, Saman; Savenije, Hubert; Gupta, Hoshin; Wheater, Howard

2016-04-01

Environmental models are abstract simplifications of real systems. As a result, the elements of these models, including system architecture (structure), process parameterization and parameters inherit a high level of approximation and simplification. In a conventional model building exercise the parameter values are the only elements of a model which can vary while the rest of the modeling elements are often fixed a priori and therefore not subjected to change. Once chosen the process parametrization and model structure usually remains the same throughout the modeling process. The only flexibility comes from the changing parameter values, thereby enabling these models to reproduce the desired observation. This part of modeling practice, parameter identification and uncertainty, has attracted a significant attention in the literature during the last years. However what remains unexplored in our point of view is to what extent the process parameterization and system architecture (model structure) can support each other. In other words "Does a specific form of process parameterization emerge for a specific model given its system architecture and data while no or little assumption has been made about the process parameterization itself? In this study we relax the assumption regarding a specific pre-determined form for the process parameterizations of a rainfall/runoff model and examine how varying the complexity of the system architecture can lead to different or possibly contradictory parameterization forms than what would have been decided otherwise. This comparison implicitly and explicitly provides us with an assessment of how uncertain is our perception of model process parameterization in respect to the extent the data can support.

Sensitivity of Pacific Cold Tongue and Double-ITCZ Bias to Convective Parameterization

NASA Astrophysics Data System (ADS)

Woelfle, M.; Bretherton, C. S.; Pritchard, M. S.; Yu, S.

2016-12-01

Many global climate models struggle to accurately simulate annual mean precipitation and sea surface temperature (SST) fields in the tropical Pacific basin. Precipitation biases are dominated by the double intertropical convergence zone (ITCZ) bias where models exhibit precipitation maxima straddling the equator while only a single Northern Hemispheric maximum exists in observations. The major SST bias is the enhancement of the equatorial cold tongue. A series of coupled model simulations are used to investigate the sensitivity of the bias development to convective parameterization. Model components are initialized independently prior to coupling to allow analysis of the transient response of the system directly following coupling. These experiments show precipitation and SST patterns to be highly sensitive to convective parameterization. Simulations in which the deep convective parameterization is disabled forcing all convection to be resolved by the shallow convection parameterization showed a degradation in both the cold tongue and double-ITCZ biases as precipitation becomes focused into off-equatorial regions of local SST maxima. Simulations using superparameterization in place of traditional cloud parameterizations showed a reduced cold tongue bias at the expense of additional precipitation biases. The equatorial SST responses to changes in convective parameterization are driven by changes in near equatorial zonal wind stress. The sensitivity of convection to SST is important in determining the precipitation and wind stress fields. However, differences in convective momentum transport also play a role. While no significant improvement is seen in these simulations of the double-ITCZ, the system's sensitivity to these changes reaffirm that improved convective parameterizations may provide an avenue for improving simulations of tropical Pacific precipitation and SST.

New Parameterizations for Neutral and Ion-Induced Sulfuric Acid-Water Particle Formation in Nucleation and Kinetic Regimes

NASA Astrophysics Data System (ADS)

Määttänen, Anni; Merikanto, Joonas; Henschel, Henning; Duplissy, Jonathan; Makkonen, Risto; Ortega, Ismael K.; Vehkamäki, Hanna

2018-01-01

We have developed new parameterizations of electrically neutral homogeneous and ion-induced sulfuric acid-water particle formation for large ranges of environmental conditions, based on an improved model that has been validated against a particle formation rate data set produced by Cosmics Leaving OUtdoor Droplets (CLOUD) experiments at European Organization for Nuclear Research (CERN). The model uses a thermodynamically consistent version of the Classical Nucleation Theory normalized using quantum chemical data. Unlike the earlier parameterizations for H2SO4-H2O nucleation, the model is applicable to extreme dry conditions where the one-component sulfuric acid limit is approached. Parameterizations are presented for the critical cluster sulfuric acid mole fraction, the critical cluster radius, the total number of molecules in the critical cluster, and the particle formation rate. If the critical cluster contains only one sulfuric acid molecule, a simple formula for kinetic particle formation can be used: this threshold has also been parameterized. The parameterization for electrically neutral particle formation is valid for the following ranges: temperatures 165-400 K, sulfuric acid concentrations 104-1013 cm-3, and relative humidities 0.001-100%. The ion-induced particle formation parameterization is valid for temperatures 195-400 K, sulfuric acid concentrations 104-1016 cm-3, and relative humidities 10-5-100%. The new parameterizations are thus applicable for the full range of conditions in the Earth's atmosphere relevant for binary sulfuric acid-water particle formation, including both tropospheric and stratospheric conditions. They are also suitable for describing particle formation in the atmosphere of Venus.

Flexibility training in preadolescent female athletes: Acute and long-term effects of intermittent and continuous static stretching.

PubMed

Donti, Οlyvia; Papia, Konstantina; Toubekis, Argyris; Donti, Anastasia; Sands, William A; Bogdanis, Gregory C

2018-07-01

This study compared the acute and long-term effects of intermittent and continuous static stretching training on straight leg raise range of motion (ROM). Seventy-seven preadolescent female gymnasts were divided into a stretching (n = 57), and a control group (n = 20). The stretching group performed static stretching of the hip extensors of both legs, three times per week for 15 weeks. One leg performed intermittent (3 × 30 s with 30 s rest) while the other leg performed continuous stretching (90 s). ROM pre- and post-stretching was measured at baseline, on weeks 3, 6, 9, 12, 15 and after 2 weeks of detraining. ROM was increased during both intermittent and continuous stretching training, but remained unchanged in the control group. Intermittent stretching conferred a larger improvement in ROM compared to both continuous stretching and control from week 3, until the end of training, and following detraining (p = 0.045 to 0.001 and d = 0.80 to 1.41). During detraining, ROM after the intermittent protocol decreased (p = 0.001), while it was maintained after the continuous protocol (p = 0.36). Acute increases in ROM following the intermittent stretching were also larger than in the continuous (p = 0.038). Intermittent stretching was more effective than continuous, for both long-term and acute ROM enhancement in preadolescent female athletes.

Effects of stress fiber contractility on uniaxial stretch guiding mitosis orientation and stress fiber alignment.

PubMed

Zhao, Lei; Sang, Chen; Yang, Chun; Zhuang, Fengyuan

2011-09-02

It has been documented that mitosis orientation (MO) is guided by stress fibers (SFs), which are perpendicular to exogenous cyclic uniaxial stretch. However, the effect of mechanical forces on MO and the mechanism of stretch-induced SFs reorientation are not well elucidated to date. In the present study, we used murine 3T3 fibroblasts as a model, to investigate the effects of uniaxial stretch on SFO and MO utilizing custom-made stretch device. We found that cyclic uniaxial stretch induced both SFs and mitosis directions orienting perpendicularly to the stretch direction. The F-actin and myosin II blockages, which resulted in disoriented SFs and mitosis directions under uniaxial stretch, suggested a high correlation between SFO and MO. Y27632 (10 μM), ML7 (50 μM, or 75 μM), and blebbistatin (50 μM, or 75 μM) treatments resulted in SFO parallel to the principle stretch direction. Upon stimulating and inhibiting the phosphorylation of myosin light chain (p-MLC), we observed a monotonic proportion of SFO to the level of p-MLC. These results suggested that the level of cell contraction is crucial to the response of SFs, either perpendicular or parallel, to the external stretch. Showing the possible role of cell contractility in tuning SFO under external stretch, our experimental data are valuable to understand the predominant factor controlling SFO response to exogenous uniaxial stretch, and thus helpful for improving mechanical models. Copyright © 2011 Elsevier Ltd. All rights reserved.

Building a Bridge to Deep Time: Sedimentary Systems Across Timescales

NASA Astrophysics Data System (ADS)

Romans, B.; Castelltort, S.; Covault, J. A.; Walsh, J. P.

2013-12-01

It is increasingly important to understand the complex and interdependent processes associated with sediment production, transport, and deposition at timescales relevant to civilization (annual to millennial). However, predicting the response of sedimentary systems to global environmental change across a range of timescales remains a significant challenge. For example, a significant increase in global average temperature at the Paleocene-Eocene boundary (55.8 Ma) is interpreted to have occurred over millennial timescales; however, the specific response of sedimentary systems (e.g., timing and magnitude of sediment flux variability in river systems) to that forcing is debated. Thus, using such environmental perturbations recorded in sedimentary archives as analogs for ongoing/future global change requires improved approaches to bridging across time. Additionally, the ability to bridge timescales is critical for addressing other questions about sedimentary system behavior, including signal propagation and signal versus ';noise' in the record. The geologic record provides information that can be used to develop a comprehensive understanding of process-response behavior at multiple timescales. The geomorphic ';snapshot' of present-day erosional and depositional landscapes can be examined to reconstruct the history of processes that created the observable configurations. Direct measurement and monitoring of active processes are used to constrain conceptual and numerical models and develop sedimentary system theory. But real-time observations of active Earth-surface processes are limited to the very recent, and how such processes integrate over longer timescales to transform into strata remains unknown. At longer timescales (>106 yr), the stratigraphic record is the only vestige of ancient sedimentary systems. Stratigraphic successions contain a complex record of sediment deposition and preservation, as well as the detrital material that originated in long since denuded orogenic belts. Moreover, as the timescale of the duration of the process-response behavior and/or system age increase, additional aspects must be considered (e.g., significant tectonic regime change, rare but significant events, non-periodic global change, etc.). In this presentation we discuss several examples of sedimentary system analysis at different timescales with the goal of highlighting various approaches at one timescale and how they can (or cannot) be applied for questions at different timescales. Examples include: (1) brief review of decadal to centennial sediment budgets; (2) land-to-sea sediment budget reconstructions from southern California at millennial to multi-millennial timescales, and (3) sedimentary system response to climatic and tectonic forcings at ≥105 yr timescales.

Parameterization of ALMANAC crop simulation model for non-irrigated dry bean in semi-arid temperate areas in Mexico

USDA-ARS?s Scientific Manuscript database

Simulation models can be used to make management decisions when properly parameterized. This study aimed to parameterize the ALMANAC (Agricultural Land Management Alternatives with Numerical Assessment Criteria) crop simulation model for dry bean in the semi-arid temperate areas of Mexico. The par...

A parameterization scheme for the x-ray linear attenuation coefficient and energy absorption coefficient.

PubMed

Midgley, S M

2004-01-21

A novel parameterization of x-ray interaction cross-sections is developed, and employed to describe the x-ray linear attenuation coefficient and mass energy absorption coefficient for both elements and mixtures. The new parameterization scheme addresses the Z-dependence of elemental cross-sections (per electron) using a simple function of atomic number, Z. This obviates the need for a complicated mathematical formalism. Energy dependent coefficients describe the Z-direction curvature of the cross-sections. The composition dependent quantities are the electron density and statistical moments describing the elemental distribution. We show that it is possible to describe elemental cross-sections for the entire periodic table and at energies above the K-edge (from 6 keV to 125 MeV), with an accuracy of better than 2% using a parameterization containing not more than five coefficients. For the biologically important elements 1 < or = Z < or = 20, and the energy range 30-150 keV, the parameterization utilizes four coefficients. At higher energies, the parameterization uses fewer coefficients with only two coefficients needed at megavoltage energies.

Duration Dependent Effect of Static Stretching on Quadriceps and Hamstring Muscle Force.

PubMed

Alizadeh Ebadi, Leyla; Çetin, Ebru

2018-03-13

The aim of this study was to determine the acute effect of static stretching on hamstring and quadriceps muscles' isokinetic strength when applied for various durations to elite athletes, to investigate the effect of different static stretching durations on isokinetic strength, and finally to determine the optimal stretching duration. Fifteen elite male athletes from two different sport branches (10 football and five basketball) participated in this study. Experimental protocol was designed as 17 repetitive static stretching exercises for hamstring and quadriceps muscle groups according to the indicated experimental protocols; ((A) 5 min jogging; (B) 5 min jogging followed by 15 s static stretching; (C) 5 min jogging followed by 30 s static stretching; (D) 5 min jogging, followed by static stretching for 45 s). Immediately after each protocol, an isokinetic strength test consisting of five repetitions at 60°/s speed and 20 repetitions at 180°/s speed was recorded for the right leg by the Isomed 2000 device. Friedman variance analysis test was employed for data analysis. According to the analyzes, it was observed that 5 min jogging and 15 s stretching exercises increased the isokinetic strength, whereas 30 and 45 s stretching exercises caused a decrease.

Duration Dependent Effect of Static Stretching on Quadriceps and Hamstring Muscle Force

PubMed Central

Çetin, Ebru

2018-01-01

The aim of this study was to determine the acute effect of static stretching on hamstring and quadriceps muscles’ isokinetic strength when applied for various durations to elite athletes, to investigate the effect of different static stretching durations on isokinetic strength, and finally to determine the optimal stretching duration. Fifteen elite male athletes from two different sport branches (10 football and five basketball) participated in this study. Experimental protocol was designed as 17 repetitive static stretching exercises for hamstring and quadriceps muscle groups according to the indicated experimental protocols; ((A) 5 min jogging; (B) 5 min jogging followed by 15 s static stretching; (C) 5 min jogging followed by 30 s static stretching; (D) 5 min jogging, followed by static stretching for 45 s). Immediately after each protocol, an isokinetic strength test consisting of five repetitions at 60°/s speed and 20 repetitions at 180°/s speed was recorded for the right leg by the Isomed 2000 device. Friedman variance analysis test was employed for data analysis. According to the analyzes, it was observed that 5 min jogging and 15 s stretching exercises increased the isokinetic strength, whereas 30 and 45 s stretching exercises caused a decrease.

Mechanical stretch endows mesenchymal stem cells stronger angiogenic and anti-apoptotic capacities via NFκB activation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhu, Zhuoli; Gan, Xueqi; Fan, Hongyi

Mesenchymal stem cells (MSCs) have been broadly used for tissue regeneration and repair due to their broad differentiation potential and potent paracrine properties such as angiogenic capacity. Strategies to increase their survival rate after transplantation and the angiogenic ability are of priority for the utility of MSCs. In this study, we found that mechanical stretch (10% extension, 30 cycles/min cyclic stretch) preconditioning increase the angiogenic capacity via VEGFA induction. In addition, mechanical stretch also increases the survival rate of mesenchymal stem cells under nutrients deprivation. Consistent with the increase VEGFA expression and resistance to apoptosis, nuclear localization of NFκB activity p65more » increased upon mechanical stretch. Inhibition of NFκB activity by BAY 11-708 blocks the pro-angiogenesis and anti-apoptosis function of mechanical stretch. Taken together, our findings here raise the possibility that mechanical stretch preconditioning might enhance the therapeutic efficacy of mesenchymal stem cells. - Highlights: • Mechanical stretch increases the angiogenic capacity via VEGFA induction in MSCs. • Mechanical stretch increases the survival rate of MSCs under nutrients deprivation. • Mechanical stretch manipulates MSCs via the activation of NFκB.« less

Acute effect of stretching one leg on regional arterial stiffness in young men.

PubMed

Yamato, Yosuke; Hasegawa, Natsuki; Fujie, Shumpei; Ogoh, Shigehiko; Iemitsu, Motoyuki

2017-06-01

Our previous study demonstrated that a single bout of stretching exercises acutely reduced arterial stiffness. We hypothesized that this acute vascular response is due to regional mechanical stimulation of the peripheral arteries. To test this hypothesis, we examined the effect of a single bout of passive one leg stretching on arterial stiffness, comparing the stretched and the non-stretched leg in the same subject. Twenty-five healthy young men (20.9 ± 0.3 years, 172.5 ± 1.4 cm, 64.1 ± 1.2 kg) volunteered for the study. Subjects underwent a passive calf stretching on one leg (six repetitions of 30-s static stretch with a 10-s recovery). Pulse wave velocity (PWV, an index of arterial stiffness), blood pressure (BP), and heart rate (HR) were measured before and immediately, 15, and 30 min after the stretching. Femoral-ankle PWV (faPWV) in the stretched leg was significantly decreased from baseline (835.0 ± 15.9 cm/s) to immediately (802.9 ± 16.8 cm/s, P < 0.01) and 15 min (810.5 ± 16.0 cm/s, P < 0.01) after the stretching, despite no changes in systolic and diastolic BP, or HR. However, faPWV in the non-stretched leg was not significantly altered at any time. Brachial-ankle PWV (baPWV) also showed similar responses with faPWV, but this response was not significant. Additionally, the passive stretching did not alter carotid-femoral PWV (cfPWV). These results suggest that mechanical stimulation to peripheral arteries as induced by static passive stretch may modulate arterial wall properties directly, rather than resulting in a systemic effect.

Comparison of effects of static, proprioceptive neuromuscular facilitation and Mulligan stretching on hip flexion range of motion: a randomized controlled trial.

PubMed

Yıldırım, M S; Ozyurek, S; Tosun, Oç; Uzer, S; Gelecek, N

2016-03-01

The aim of this study was to compare the effects of static stretching, proprioceptive neuromuscular facilitation (PNF) stretching and Mulligan technique on hip flexion range of motion (ROM) in subjects with bilateral hamstring tightness. A total of 40 students (mean age: 21.5±1.3 years, mean body height: 172.8±8.2 cm, mean body mass index: 21.9±3.0 kg · m(-2)) with bilateral hamstring tightness were enrolled in this randomized trial, of whom 26 completed the study. Subjects were divided into 4 groups performing (I) typical static stretching, (II) PNF stretching, (III) Mulligan traction straight leg raise (TSLR) technique, (IV) no intervention. Hip flexion ROM was measured using a digital goniometer with the passive straight leg raise test before and after 4 weeks by two physiotherapists blinded to the groups. 52 extremities of 26 subjects were analyzed. Hip flexion ROM increased in all three intervention groups (p<0.05) but not in the no-intervention group after 4 weeks. A statistically significant change in initial-final assessment differences of hip flexion ROM was found between groups (p<0.001) in favour of PNF stretching and Mulligan TSLR technique in comparison to typical static stretching (p=0.016 and p=0.02, respectively). No significant difference was found between Mulligan TSLR technique and PNF stretching (p=0.920). The initial-final assessment difference of hip flexion ROM was similar in typical static stretching and no intervention (p=0.491). A 4-week stretching intervention is beneficial for increasing hip flexion ROM in bilateral hamstring tightness. However, PNF stretching and Mulligan TSLR technique are superior to typical static stretching. These two interventions can be alternatively used for stretching in hamstring tightness.

The effects of passive stretching plus vibration on strength and activation of the plantar flexors.

PubMed

Miller, Jonathan D; Herda, Trent J; Trevino, Michael A; Mosier, Eric M

2016-09-01

This study examined the effects of passive stretching only (PS+CON) and passive stretching with the addition of continuous vibration (VIB) during post-passive stretching tests (PS+VIB) on peak torque (PT), percent voluntary inactivation (%VI), single stimulus twitch torque (TTSINGLE), and doublet stimuli twitch torque (TTDOUBLET) of the plantar flexors at a short (20° plantar flexion (PF)) and long muscle length (15° dorsiflexion (DF)). Fourteen healthy men (age = 22 ± 3 years) performed isometric maximal voluntary contractions at PF and DF, and passive range of motion (PROM) assessments before and after 8 × 30-s passive stretches without (PS+CON) or with VIB (PS+VIB) administered continuously throughout post-passive stretching tests. The passive properties of the muscle tendon unit were assessed pre- and post-passive stretching via PROM, passive torque (PASSTQ), and musculotendinous stiffness (MTS) measurements. PT, TTSINGLE, and TTDOUBLET decreased, whereas, %VI increased following passive stretching at PF and DF (P < 0.05) with no significant differences between PS+CON and PS+VIB. PASSTQ and MTS decreased while PROM increased post-passive stretching during both trials (P < 0.05). The stretching-induced force/torque deficit and increases in %VI were evident following passive stretching at short and long muscle lengths. Although not statistically significant, effect size calculations suggested large and moderate differences in the absolute changes in PT (Cohen's d = 1.14) and %VI (Cohen's d = 0.54) from pre- to post-passive stretching between treatments, with PS+VIB having greater decreases of PT and higher %VI than PS+CON. The decrement in PT following passive stretching may be primarily neural in origin.

Comparison of effects of static, proprioceptive neuromuscular facilitation and Mulligan stretching on hip flexion range of motion: a randomized controlled trial

PubMed Central

Ozyurek, S; Tosun, OÇ; Uzer, S; Gelecek, N

2016-01-01

The aim of this study was to compare the effects of static stretching, proprioceptive neuromuscular facilitation (PNF) stretching and Mulligan technique on hip flexion range of motion (ROM) in subjects with bilateral hamstring tightness. A total of 40 students (mean age: 21.5±1.3 years, mean body height: 172.8±8.2 cm, mean body mass index: 21.9±3.0 kg · m-2) with bilateral hamstring tightness were enrolled in this randomized trial, of whom 26 completed the study. Subjects were divided into 4 groups performing (I) typical static stretching, (II) PNF stretching, (III) Mulligan traction straight leg raise (TSLR) technique, (IV) no intervention. Hip flexion ROM was measured using a digital goniometer with the passive straight leg raise test before and after 4 weeks by two physiotherapists blinded to the groups. 52 extremities of 26 subjects were analyzed. Hip flexion ROM increased in all three intervention groups (p<0.05) but not in the no-intervention group after 4 weeks. A statistically significant change in initial–final assessment differences of hip flexion ROM was found between groups (p<0.001) in favour of PNF stretching and Mulligan TSLR technique in comparison to typical static stretching (p=0.016 and p=0.02, respectively). No significant difference was found between Mulligan TSLR technique and PNF stretching (p=0.920). The initial–final assessment difference of hip flexion ROM was similar in typical static stretching and no intervention (p=0.491). A 4-week stretching intervention is beneficial for increasing hip flexion ROM in bilateral hamstring tightness. However, PNF stretching and Mulligan TSLR technique are superior to typical static stretching. These two interventions can be alternatively used for stretching in hamstring tightness. PMID:26929476

Developmental axon stretch stimulates neuron growth while maintaining normal electrical activity, intracellular calcium flux, and somatic morphology

PubMed Central

Loverde, Joseph R.; Pfister, Bryan J.

2015-01-01

Elongation of nerve fibers intuitively occurs throughout mammalian development, and is synchronized with expansion of the growing body. While most tissue systems enlarge through mitosis and differentiation, elongation of nerve fibers is remarkably unique. The emerging paradigm suggests that axons undergo stretch as contiguous tissues enlarge between the proximal and distal segments of spanning nerve fibers. While stretch is distinct from growth, tension is a known stimulus which regulates the growth of axons. Here, we hypothesized that the axon stretch-growth process may be a natural form of injury, whereby regenerative processes fortify elongating axons in order to prevent disconnection. Harnessing the live imaging capability of our axon stretch-growth bioreactors, we assessed neurons both during and following stretch for biomarkers associated with injury. Utilizing whole-cell patch clamp recording, we found no evidence of changes in spontaneous action potential activity or degradation of elicited action potentials during real-time axon stretch at strains of up to 18% applied over 5 min. Unlike traumatic axonal injury, functional calcium imaging of the soma revealed no shifts in free intracellular calcium during axon stretch. Finally, the cross-sectional areas of nuclei and cytoplasms were normal, with no evidence of chromatolysis following week-long stretch-growth limited to the lower of 25% strain or 3 mm total daily stretch. The neuronal growth cascade coupled to stretch was concluded to be independent of the changes in membrane potential, action potential generation, or calcium flux associated with traumatic injury. While axon stretch-growth is likely to share overlap with regenerative processes, we conclude that developmental stretch is a distinct stimulus from traumatic axon injury. PMID:26379492

Lewis lung carcinoma regulation of mechanical stretch-induced protein synthesis in cultured myotubes.

PubMed

Gao, Song; Carson, James A

2016-01-01

Mechanical stretch can activate muscle and myotube protein synthesis through mammalian target of rapamycin complex 1 (mTORC1) signaling. While it has been established that tumor-derived cachectic factors can induce myotube wasting, the effect of this catabolic environment on myotube mechanical signaling has not been determined. We investigated whether media containing cachectic factors derived from Lewis lung carcinoma (LLC) can regulate the stretch induction of myotube protein synthesis. C2C12 myotubes preincubated in control or LLC-derived media were chronically stretched. Protein synthesis regulation by anabolic and catabolic signaling was then examined. In the control condition, stretch increased mTORC1 activity and protein synthesis. The LLC treatment decreased basal mTORC1 activity and protein synthesis and attenuated the stretch induction of protein synthesis. LLC media increased STAT3 and AMP-activated protein kinase phosphorylation in myotubes, independent of stretch. Both stretch and LLC independently increased ERK1/2, p38, and NF-κB phosphorylation. In LLC-treated myotubes, the inhibition of ERK1/2 and p38 rescued the stretch induction of protein synthesis. Interestingly, either leukemia inhibitory factor or glycoprotein 130 antibody administration caused further inhibition of mTORC1 signaling and protein synthesis in stretched myotubes. AMP-activated protein kinase inhibition increased basal mTORC1 signaling activity and protein synthesis in LLC-treated myotubes, but did not restore the stretch induction of protein synthesis. These results demonstrate that LLC-derived cachectic factors can dissociate stretch-induced signaling from protein synthesis through ERK1/2 and p38 signaling, and that glycoprotein 130 signaling is associated with the basal stretch response in myotubes. Copyright © 2016 the American Physiological Society.

A unified spectral,parameterization for wave breaking: from the deep ocean to the surf zone

NASA Astrophysics Data System (ADS)

Filipot, J.

2010-12-01

A new wave-breaking dissipation parameterization designed for spectral wave models is presented. It combines wave breaking basic physical quantities, namely, the breaking probability and the dissipation rate per unit area. The energy lost by waves is fi[|#12#|]rst calculated in the physical space before being distributed over the relevant spectral components. This parameterization allows a seamless numerical model from the deep ocean into the surf zone. This transition from deep to shallow water is made possible by a dissipation rate per unit area of breaking waves that varies with the wave height, wavelength and water depth.The parameterization is further tested in the WAVEWATCH III TM code, from the global ocean to the beach scale. Model errors are smaller than with most specialized deep or shallow water parameterizations.

Methods of testing parameterizations: Vertical ocean mixing

NASA Technical Reports Server (NTRS)

Tziperman, Eli

1992-01-01

The ocean's velocity field is characterized by an exceptional variety of scales. While the small-scale oceanic turbulence responsible for the vertical mixing in the ocean is of scales a few centimeters and smaller, the oceanic general circulation is characterized by horizontal scales of thousands of kilometers. In oceanic general circulation models that are typically run today, the vertical structure of the ocean is represented by a few tens of discrete grid points. Such models cannot explicitly model the small-scale mixing processes, and must, therefore, find ways to parameterize them in terms of the larger-scale fields. Finding a parameterization that is both reliable and plausible to use in ocean models is not a simple task. Vertical mixing in the ocean is the combined result of many complex processes, and, in fact, mixing is one of the less known and less understood aspects of the oceanic circulation. In present models of the oceanic circulation, the many complex processes responsible for vertical mixing are often parameterized in an oversimplified manner. Yet, finding an adequate parameterization of vertical ocean mixing is crucial to the successful application of ocean models to climate studies. The results of general circulation models for quantities that are of particular interest to climate studies, such as the meridional heat flux carried by the ocean, are quite sensitive to the strength of the vertical mixing. We try to examine the difficulties in choosing an appropriate vertical mixing parameterization, and the methods that are available for validating different parameterizations by comparing model results to oceanographic data. First, some of the physical processes responsible for vertically mixing the ocean are briefly mentioned, and some possible approaches to the parameterization of these processes in oceanographic general circulation models are described in the following section. We then discuss the role of the vertical mixing in the physics of the large-scale ocean circulation, and examine methods of validating mixing parameterizations using large-scale ocean models.

Disruption of Locomotion in Response to Hindlimb Muscle Stretch at Acute and Chronic Time Points after a Spinal Cord Injury in Rats.

PubMed

Keller, Anastasia V P; Wainwright, Grace; Shum-Siu, Alice; Prince, Daniella; Hoeper, Alyssa; Martin, Emily; Magnuson, David S K

2017-02-01

After spinal cord injury (SCI) muscle contractures develop in the plegic limbs of many patients. Physical therapists commonly use stretching as an approach to avoid contractures and to maintain the extensibility of soft tissues. We found previously that a daily stretching protocol has a negative effect on locomotor recovery in rats with mild thoracic SCI. The purpose of the current study was to determine the effects of stretching on locomotor function at acute and chronic time points after moderately severe contusive SCI. Female Sprague-Dawley rats with 25 g-cm T10 contusion injuries received our standard 24-min stretching protocol starting 4 days (acutely) or 10 weeks (chronically) post-injury (5 days/week for 5 or 4 weeks, respectively). Locomotor function was assessed using the BBB (Basso, Beattie, and Bresnahan) Open Field Locomotor Scale, video-based kinematics, and gait analysis. Locomotor deficits were evident in the acute animals after only 5 days of stretching and increasing the perceived intensity of stretching at week 4 resulted in greater impairment. Stretching initiated chronically resulted in dramatic decrements in locomotor function because most animals had BBB scores of 0-3 for weeks 2, 3, and 4 of stretching. Locomotor function recovered to control levels for both groups within 2 weeks once daily stretching ceased. Histological analysis revealed no apparent signs of overt and persistent damage to muscles undergoing stretching. The current study extends our observations of the stretching phenomenon to a more clinically relevant moderately severe SCI animal model. The results are in agreement with our previous findings and further demonstrate that spinal cord locomotor circuitry is especially vulnerable to the negative effects of stretching at chronic time points. While the clinical relevance of this phenomenon remains unknown, we speculate that stretching may contribute to the lack of locomotor recovery in some patients.

No Effect of Muscle Stretching within a Full, Dynamic Warm-up on Athletic Performance.

PubMed

Blazevich, Anthony J; Gill, Nicholas D; Kvorning, Thue; Kay, Anthony D; Goh, Alvin G; Hilton, Bradley; Drinkwater, Eric J; Behm, David G

2018-06-01

This study aimed to examine the effects of static and dynamic stretching routines performed as part of a comprehensive warm-up on flexibility and sprint running, jumping, and change of direction tests in team sport athletes. A randomized, controlled, crossover study design with experimenter blinding was conducted. On separate days, 20 male team sport athletes completed a comprehensive warm-up routine. After a low-intensity warm-up, a 5-s static stretch (5S), a 30-s static stretch (30S; 3 × 10-s stretches), a 5-repetition (per muscle group) dynamic stretch (DYN), or a no-stretch (NS) protocol was completed; stretches were done on seven lower body and two upper body regions. This was followed by test-specific practice progressing to maximum intensity. A comprehensive test battery assessing intervention effect expectations as well as flexibility, vertical jump, sprint running, and change of direction outcomes was then completed in a random order. There were no effects of stretch condition on test performances. Before the study, 18/20 participants nominated DYN as the most likely to improve performance and 15/20 nominated NS as least likely. Immediately before testing, NS was rated less "effective" (4.0 ± 2.2 on a 10-point scale) than 5S, 30S, and DYN (5.3-6.4). Nonetheless, these ratings were not related to test performances. Participants felt they were more likely to perform well when stretching was performed as part of the warm-up, irrespective of stretch type. However, no effect of muscle stretching was observed on flexibility and physical function compared with no stretching. On the basis of the current evidence, the inclusion of short durations of either static or dynamic stretching is unlikely to affect sprint running, jumping, or change of direction performance when performed as part of a comprehensive physical preparation routine.

Stretch-Induced Hypertrophy Activates NFkB-Mediated VEGF Secretion in Adult Cardiomyocytes

PubMed Central

Leychenko, Anna; Konorev, Eugene; Jijiwa, Mayumi; Matter, Michelle L.

2011-01-01

Hypertension and myocardial infarction are associated with the onset of hypertrophy. Hypertrophy is a compensatory response mechanism to increases in mechanical load due to pressure or volume overload. It is characterized by extracellular matrix remodeling and hypertrophic growth of adult cardiomyocytes. Production of Vascular Endothelial Growth Factor (VEGF), which acts as an angiogenic factor and a modulator of cardiomyocyte function, is regulated by mechanical stretch. Mechanical stretch promotes VEGF secretion in neonatal cardiomyocytes. Whether this effect is retained in adult cells and the molecular mechanism mediating stretch-induced VEGF secretion has not been elucidated. Our objective was to investigate whether cyclic mechanical stretch induces VEGF secretion in adult cardiomyocytes and to identify the molecular mechanism mediating VEGF secretion in these cells. Isolated primary adult rat cardiomyocytes (ARCMs) were subjected to cyclic mechanical stretch at an extension level of 10% at 30 cycles/min that induces hypertrophic responses. Cyclic mechanical stretch induced a 3-fold increase in VEGF secretion in ARCMs compared to non-stretch controls. This increase in stretch-induced VEGF secretion correlated with NFkB activation. Cyclic mechanical stretch-mediated VEGF secretion was blocked by an NFkB peptide inhibitor and expression of a dominant negative mutant IkBα, but not by inhibitors of the MAPK/ERK1/2 or PI3K pathways. Chromatin immunoprecipitation assays demonstrated an interaction of NFkB with the VEGF promoter in stretched primary cardiomyocytes. Moreover, VEGF secretion is increased in the stretched myocardium during pressure overload-induced hypertrophy. These findings are the first to demonstrate that NFkB activation plays a role in mediating VEGF secretion upon cyclic mechanical stretch in adult cardiomyocytes. Signaling by NFkB initiated in response to cyclic mechanical stretch may therefore coordinate the hypertrophic response in adult cardiomyocytes. Elucidation of this novel mechanism may provide a target for developing future pharmacotherapy to treat hypertension and heart disease. PMID:22174951

Pulmonary atelectasis during low stretch ventilation: "open lung" versus "lung rest" strategy.

PubMed

Fanelli, Vito; Mascia, Luciana; Puntorieri, Valeria; Assenzio, Barbara; Elia, Vincenzo; Fornaro, Giancarlo; Martin, Erica L; Bosco, Martino; Delsedime, Luisa; Fiore, Tommaso; Grasso, Salvatore; Ranieri, V Marco

2009-03-01

Limiting tidal volume (VT) may minimize ventilator-induced lung injury (VILI). However, atelectasis induced by low VT ventilation may cause ultrastructural evidence of cell disruption. Apoptosis seems to be involved as protective mechanisms from VILI through the involvement of mitogen-activated protein kinases (MAPKs). We examined the hypothesis that atelectasis may influence the response to protective ventilation through MAPKs. Prospective randomized study. University animal laboratory. Adult male 129/Sv mice. Isolated, nonperfused lungs were randomized to VILI: VT of 20 mL/kg and positive end-expiratory pressure (PEEP) zero; low stretch/lung rest: VT of 6 mL/kg and 8-10 cm H2O of PEEP; low stretch/open lung: VT of 6 mL/kg, two recruitment maneuvers and 14-16 cm H2O of PEEP. Ventilator settings were adjusted using the stress index. Both low stretch strategies equally blunted the VILI-induced derangement of respiratory mechanics (static volume-pressure curve), lung histology (hematoxylin and eosin), and inflammatory mediators (interleukin-6, macrophage inflammatory protein-2 [enzyme-linked immunosorbent assay], and inhibitor of nuclear factor-kB[Western blot]). VILI caused nuclear swelling and membrane disruption of pulmonary cells (electron microscopy). Few pulmonary cells with chromatin condensation and fragmentation were seen during both low stretch strategies. However, although cell thickness during low stretch/open lung was uniform, low stretch/lung rest demonstrated thickening of epithelial cells and plasma membrane bleb formation. Compared with the low stretch/open lung, low stretch/lung rest caused a significant decrease in apoptotic cells (terminal deoxynucleotidyl transferase mediated deoxyuridine-triphosphatase nick end-labeling) and tissue expression of caspase-3 (Western blot). Both low stretch strategies attenuated the activation of MAPKs. Such reduction was larger during low stretch/open lung than during low stretch/lung rest (p < 0.001). Low stretch strategies provide similar attenuation of VILI. However, low stretch/lung rest strategy is associated to less apoptosis and more ultrastructural evidence of cell damage possibly through MAPKs-mediated pathway.

Acute Effects of Different Agonist and Antagonist Stretching Arrangements on Static and Dynamic Range of Motion.

PubMed

Amiri-Khorasani, Mohammadtaghi; Kellis, Eleftherios

2015-12-01

Traditionally, stretching exercises are considered as basic components of warm up aiming to prepare the musculoskeletal system for performance and to prevent injuries. The purpose of this study was to examine the effects of different agonist and antagonist stretching arrangements within a pre-exercise warm-up on hip static (SROM) and dynamic range of motion (DROM). Sixty trained male subjects (Mean ± SD: height, 177.38 ± 6.92 cm; body mass, 68.4 ± 10.22 kg; age, 21.52 ± 1.17 years) volunteered to participate in this study. SROM was measured by V-sit test and DROM captured by a motion analysis system before and after (i) static stretching for both hip flexor and extensor muscles (SFSE), (ii) dynamic stretching for both hip flexor and extensor muscles (DFDE), (iii) static stretching for the hip flexors and dynamic stretching for hip extensors (SFDE), and (iv) dynamic stretching for the hip flexors and static stretching for hip extensors (DFSE). DFSE showed a significantly higher increase in DROM and SROM than the remainder of the stretching protocols (P < 0.05). There were significant differences between DFDE with SFSE and SFDE (P < 0.05) and SFSE showed significant increase as compared to SFDE (P < 0.05). In conclusion, DFSE is probably the best stretching arrangement due to producing more post activation potentiation on agonist muscles and less muscle stiffness in antagonist muscles.

Effects of cervical self-stretching on slow vital capacity.

PubMed

Han, Dongwook; Yoon, Nayoon; Jeong, Yeongran; Ha, Misook; Nam, Kunwoo

2015-07-01

[Purpose] This study investigated the effects of self-stretching of cervical muscles, because the accessory inspiratory muscle is considered to improve pulmonary function. [Subjects] The subjects were 30 healthy university students 19-21 years old who did not have any lung disease, respiratory dysfunction, cervical injury, or any problems upon cervical stretching. [Methods] Spirometry was used as a pulmonary function test to measure the slow vital capacity before and after stretching. The slow vital capacity of the experimental group was measured before and after cervical self-stretching. Meanwhile, the slow vital capacity of the control group, which did not perform stretching, was also measured before and after the intervention. [Results] The expiratory vital capacity, inspiratory reserve volume, and expiratory reserve volume of the experimental group increased significantly after the cervical self-stretching. [Conclusion] Self-stretching of the cervical muscle (i.e., the inspiratory accessory muscle) improves slow vital capacity.

Endovascular rescue method for undesirably stretched coil.

PubMed

Cho, Jae Hoon

2014-10-01

Undesirable detachment or stretching of coils within the parent artery during aneurysm embolization can be related with thrombus formation, which can be caused occlusion of parent artery or embolic event(s). To escape from this situation, several rescue methods have been reported. A case with undesirably stretched coil in which another rescue method was used, is presented. When the stretched coil is still located in the coil delivery microcatheter, the stretched coil can be removed safely using a snare and a handmade monorail microcatheter. After a snare is lodged in the handmade monorail microcatheter, the snare is introduced over the coil delivery micorcatheter and located in the distal part of the stretched coil. After then, the handmade monorail microcatheter captures the stretched coil and the snare as one unit. This technique using a handmade monorail microcatheter and a snare can be a good rescue modality for the undesirably stretched coil, still remained within the coil delivery microcatheter.

Endovascular Rescue Method for Undesirably Stretched Coil

PubMed Central

2014-01-01

Undesirable detachment or stretching of coils within the parent artery during aneurysm embolization can be related with thrombus formation, which can be caused occlusion of parent artery or embolic event(s). To escape from this situation, several rescue methods have been reported. A case with undesirably stretched coil in which another rescue method was used, is presented. When the stretched coil is still located in the coil delivery microcatheter, the stretched coil can be removed safely using a snare and a handmade monorail microcatheter. After a snare is lodged in the handmade monorail microcatheter, the snare is introduced over the coil delivery micorcatheter and located in the distal part of the stretched coil. After then, the handmade monorail microcatheter captures the stretched coil and the snare as one unit. This technique using a handmade monorail microcatheter and a snare can be a good rescue modality for the undesirably stretched coil, still remained within the coil delivery microcatheter. PMID:25371791

Comparison of Gravity Wave Temperature Variances from Ray-Based Spectral Parameterization of Convective Gravity Wave Drag with AIRS Observations

NASA Technical Reports Server (NTRS)

Choi, Hyun-Joo; Chun, Hye-Yeong; Gong, Jie; Wu, Dong L.

2012-01-01

The realism of ray-based spectral parameterization of convective gravity wave drag, which considers the updated moving speed of the convective source and multiple wave propagation directions, is tested against the Atmospheric Infrared Sounder (AIRS) onboard the Aqua satellite. Offline parameterization calculations are performed using the global reanalysis data for January and July 2005, and gravity wave temperature variances (GWTVs) are calculated at z = 2.5 hPa (unfiltered GWTV). AIRS-filtered GWTV, which is directly compared with AIRS, is calculated by applying the AIRS visibility function to the unfiltered GWTV. A comparison between the parameterization calculations and AIRS observations shows that the spatial distribution of the AIRS-filtered GWTV agrees well with that of the AIRS GWTV. However, the magnitude of the AIRS-filtered GWTV is smaller than that of the AIRS GWTV. When an additional cloud top gravity wave momentum flux spectrum with longer horizontal wavelength components that were obtained from the mesoscale simulations is included in the parameterization, both the magnitude and spatial distribution of the AIRS-filtered GWTVs from the parameterization are in good agreement with those of the AIRS GWTVs. The AIRS GWTV can be reproduced reasonably well by the parameterization not only with multiple wave propagation directions but also with two wave propagation directions of 45 degrees (northeast-southwest) and 135 degrees (northwest-southeast), which are optimally chosen for computational efficiency.

The Influence of Microphysical Cloud Parameterization on Microwave Brightness Temperatures

NASA Technical Reports Server (NTRS)

Skofronick-Jackson, Gail M.; Gasiewski, Albin J.; Wang, James R.; Zukor, Dorothy J. (Technical Monitor)

2000-01-01

The microphysical parameterization of clouds and rain-cells plays a central role in atmospheric forward radiative transfer models used in calculating passive microwave brightness temperatures. The absorption and scattering properties of a hydrometeor-laden atmosphere are governed by particle phase, size distribution, aggregate density., shape, and dielectric constant. This study identifies the sensitivity of brightness temperatures with respect to the microphysical cloud parameterization. Cloud parameterizations for wideband (6-410 GHz observations of baseline brightness temperatures were studied for four evolutionary stages of an oceanic convective storm using a five-phase hydrometeor model in a planar-stratified scattering-based radiative transfer model. Five other microphysical cloud parameterizations were compared to the baseline calculations to evaluate brightness temperature sensitivity to gross changes in the hydrometeor size distributions and the ice-air-water ratios in the frozen or partly frozen phase. The comparison shows that, enlarging the rain drop size or adding water to the partly Frozen hydrometeor mix warms brightness temperatures by up to .55 K at 6 GHz. The cooling signature caused by ice scattering intensifies with increasing ice concentrations and at higher frequencies. An additional comparison to measured Convection and Moisture LA Experiment (CAMEX 3) brightness temperatures shows that in general all but, two parameterizations produce calculated T(sub B)'s that fall within the observed clear-air minima and maxima. The exceptions are for parameterizations that, enhance the scattering characteristics of frozen hydrometeors.

Statistical properties of cloud and precipitation events in Central Amazonia using GoAmazon2014/5 data: revisiting deep convection timescales.

NASA Astrophysics Data System (ADS)

Pauliquevis, T.; Alves, C. F.; Barbosa, H. M.

2016-12-01

Previous studies in Amazon have shown a clear discrepance between models and observations of convection. From the observational stand point convection in Amazonia has a typical diurnal cycle, which is characterized by shallow convection and followed by shallow to deep transition (usually in early afternoon) and rain. Differently, numerical models based in cumulus parameterizations put heavy rain in the early hours of the morning. In this context, observations are crucial both to constraint as well to validate improvement in models. In this study we investigated statistical properties of clouds, precipitation and convection employing several instruments operated during GoAmazon2014/5-DOE/ARM at Manacapuru, AM (Brazil) combined with Cloud Top Temperature data obtained by GOES. Previous studies (e.g. Adams et al., 2013) defined deep convection events as connected to rapid CTT decrease, PWV increase (convergence) and precipitation. They also observed that the average deep convection event has two characteristic time-scales of its formation, in the sense that water vapor convergence begins to build 12 hs before precipitation, with an invigoration 4 hs before rain occur. In this study we revisited this approach using GoAmazon2014/5 measurement with special focus to its statistical variability. Preliminar results for the wet season of 2014 showed that events with rapid decrease in CTT were associated with 60% of the observed precipitation at ground. Defining t0 as the central time of CTT (rapid) decrease and analyzing only events with rain volume > 10 mm it was possible to observe that precipitation maximums distributed around t0 with mean difference Δ = 24 ± 82 minutes. Most of events presented several maxima (up to 16), and the general structure was similar to beatings in oscillatory systems. In several cases eve the first maximum of rain rate was 1 hour shifted from t0. In this presentation, the above results will be discussed combined with radiometer measurements (T, RH, LWP and PWV). Special attention to differences in diurnal cycles of convective and not convective days, as well as some mean vertical profiles of those variables.

Study the sensitivity of molecular functional groups to bioethanol processing in lipid biopolymer of co-products using DRIFT molecular spectroscopy

NASA Astrophysics Data System (ADS)

Yu, Peiqiang

2011-11-01

To date, there is no study on bioethanol processing-induced changes in molecular structural profiles mainly related to lipid biopolymer. The objectives of this study were to: (1) determine molecular structural changes of lipid related functional groups in the co-products that occurred during bioethanol processing; (2) relatively quantify the antisymmetric CH 3 and CH 2 (ca. 2959 and 2928 cm -1, respectively), symmetric CH 3 and CH 2 (ca. 2871 and 2954 cm -1, respectively) functional groups, carbonyl C dbnd O ester (ca. 1745 cm -1) and unsaturated groups (CH attached to C dbnd C) (ca. 3007 cm -1) spectral intensities as well as their ratios of antisymmetric CH 3 to antisymmetric CH 2, and (3) illustrate the molecular spectral analyses as a research tool to detect for the sensitivity of individual moleculars to the bioethanol processing in a complex plant-based feed and food system without spectral parameterization. The hypothesis of this study was that bioethanol processing changed the molecular structure profiles in the co-products as opposed to original cereal grains. These changes could be detected by infrared molecular spectroscopy and will be related to nutrient utilization. The results showed that bioethanol processing had effects on the functional groups spectral profiles in the co-products. It was found that the CH 3-antisymmetric to CH 2-antisymmetric stretching intensity ratio was changed. The spectral features of carbonyl C dbnd O ester group and unsaturated group were also different. Since the different types of cereal grains (wheat vs. corn) had different sensitivity to the bioethanol processing, the spectral patterns and band component profiles differed between their co-products (wheat DDGS vs. corn DDGS). The multivariate molecular spectral analyses, cluster analysis and principal component analysis of original spectra (without spectral parameterization), distinguished the structural differences between the wheat and wheat DDGS and between the corn and corn DDGS in the antisymmetric and symmetric CH 3 and CH 2 spectral region (ca. 2994-2800 cm -1) and unsaturated group band region (3025-2996 cm -1). Further study is needed to quantify molecular structural changes in relation to nutrient utilization of lipid biopolymer.

Stretch-Oriented Polyimide Films

NASA Technical Reports Server (NTRS)

Hinkley, Jeffrey A.; Klinedinst, D.; Feuz, L.

2000-01-01

Two thermoplastic polyimides - one amorphous, the other crystallizable -- were subjected to isothermal stretching just above their glass transition temperatures. Room-temperature strengths in the stretch direction were greatly improved and, moduli increased up to 3.6-fold. Optimum stretching conditions were determined.

The application of depletion curves for parameterization of subgrid variability of snow

Treesearch

C. H. Luce; D. G. Tarboton

2004-01-01

Parameterization of subgrid-scale variability in snow accumulation and melt is important for improvements in distributed snowmelt modelling. We have taken the approach of using depletion curves that relate fractional snowcovered area to element-average snow water equivalent to parameterize the effect of snowpack heterogeneity within a physically based mass and energy...

Simultaneous Study of Mechanical Stretch-Induced Cell Proliferation and Apoptosis on C2C12 Myoblasts.

PubMed

Feng, Yu; Tian, Xiang-Yang; Sun, Peng; Cheng, Ze-Peng; Shi, Reng-Fei

2018-06-27

Mechanical stretch may cause myoblasts to either proliferate or undergo apoptosis. Identifying the molecular events that switch the fate of a stretched cell from proliferation to apoptosis is practically important in the field of regenerative medicine. A recent study on vascular smooth muscle cells illustrated that identification of these events may be achieved by addressing the stretch-induced opposite cellular outcomes simultaneously within a single investigation. To define conditions or a model in which both proliferation and apoptosis can be studied at the same time, we exposed in vitro cultured C2C12 myoblasts to a cyclic mechanical stretch regimen of 15% elongation at a stretching frequency of 1 Hz for 0, 2, 4, 6, or 8 h every day, consecutively, for 3 days. Both proliferation and apoptosis were observed. Moreover, as the duration of the stretch was prolonged, cell proliferation increased until it peaked at the optimal stretching duration. Afterwards, apoptosis gradually prevailed. Therefore, we established a model in which stretch-induced cell proliferation and apoptosis can be studied simultaneously. © 2018 S. Karger AG, Basel.

Acute effect of different stretching methods on flexibility and jumping performance in competitive artistic gymnasts.

PubMed

Dallas, G; Smirniotou, A; Tsiganos, G; Tsopani, D; Di Cagno, A; Tsolakis, Ch

2014-12-01

The purpose of this study was to investigate the acute effects of 3 different warm up methods of stretching (static, proprioceptive neuromuscular facilitation, and stretching exercises on a Vibration platform) on flexibility and legs power-jumping performance in competitive artistic gymnasts. Eighteen competitive artistic gymnasts were recruited to participate in this study. Subjects were exposed to each of 3 experimental stretching conditions: static stretching (SS), proprioceptive neuromuscular facilitation stretching (PNF), and stretching exercises on a Vibration platform (S+V). Flexibility assessed with sit and reach test (S & R) and jumping performance with squat jump (SJ) and counter movement jump (CMJ) and were measured before, immediately after and 15 min after the interventions. Significant differences were observed for flexibility after all stretching conditions for S+V (+1.1%), SS (+5.7%) and PNF (+6.8%) (P=0.000), which remained higher 15 min after interventions (S+V (1.1%), SS (5.3%) and PNF (5.5%), respectively (P=0.000). PNF stretching increased flexibility in competitive gymnasts, while S+V maintained jumping performance when both methods were used as part of a warm-up procedure.

On the Prony series representation of stretched exponential relaxation

NASA Astrophysics Data System (ADS)

Mauro, John C.; Mauro, Yihong Z.

2018-09-01

Stretched exponential relaxation is a ubiquitous feature of homogeneous glasses. The stretched exponential decay function can be derived from the diffusion-trap model, which predicts certain critical values of the fractional stretching exponent, β. In practical implementations of glass relaxation models, it is computationally convenient to represent the stretched exponential function as a Prony series of simple exponentials. Here, we perform a comprehensive mathematical analysis of the Prony series approximation of the stretched exponential relaxation, including optimized coefficients for certain critical values of β. The fitting quality of the Prony series is analyzed as a function of the number of terms in the series. With a sufficient number of terms, the Prony series can accurately capture the time evolution of the stretched exponential function, including its "fat tail" at long times. However, it is unable to capture the divergence of the first-derivative of the stretched exponential function in the limit of zero time. We also present a frequency-domain analysis of the Prony series representation of the stretched exponential function and discuss its physical implications for the modeling of glass relaxation behavior.

SmartStretch™ technology. I. Improving the tenderness of sheep topsides (m. semimembranosus) using a meat stretching device.

PubMed

Toohey, E S; van de Ven, R; Thompson, J M; Geesink, G H; Hopkins, D L

2012-06-01

This study evaluated the effect of stretching hot-boned sheep topsides using a pre-production prototype device (SmartStretch™). To test this effect, 40 sheep from 3 consignments were assessed. Left and right topsides were collected pre-rigour and randomly allocated to one of four treatments; 0 days ageing+SmartStretch™, 0 days ageing+no stretch, 5 days ageing+SmartStretch™ and 5 days ageing+no stretch. Meat from the 0 days aged+no stretch treatment was the least tender and the 5 days ageing+SmartStretch™ treatment resulted in the most tender meat. The m. semimembranosus from topsides stretched using the SmartStretch™ prototype device had a lower cooking loss percentage (P<0.001) and longer sarcomeres (P<0.001) than non-stretched m. semimembranosus. There was no effect of SmartStretch™ on myofibrillar degradation measured using particle size analysis (PSA), but there was an ageing effect (P<0.001). The tenderness of stretched m. semimembranosus showed significant improvement over non-stretched m. semimembranosus. Crown Copyright © 2012. Published by Elsevier Ltd. All rights reserved.

Signal-independent timescale analysis (SITA) and its application for neural coding during reaching and walking.

PubMed

Zacksenhouse, Miriam; Lebedev, Mikhail A; Nicolelis, Miguel A L

2014-01-01

What are the relevant timescales of neural encoding in the brain? This question is commonly investigated with respect to well-defined stimuli or actions. However, neurons often encode multiple signals, including hidden or internal, which are not experimentally controlled, and thus excluded from such analysis. Here we consider all rate modulations as the signal, and define the rate-modulations signal-to-noise ratio (RM-SNR) as the ratio between the variance of the rate and the variance of the neuronal noise. As the bin-width increases, RM-SNR increases while the update rate decreases. This tradeoff is captured by the ratio of RM-SNR to bin-width, and its variations with the bin-width reveal the timescales of neural activity. Theoretical analysis and simulations elucidate how the interactions between the recovery properties of the unit and the spectral content of the encoded signals shape this ratio and determine the timescales of neural coding. The resulting signal-independent timescale analysis (SITA) is applied to investigate timescales of neural activity recorded from the motor cortex of monkeys during: (i) reaching experiments with Brain-Machine Interface (BMI), and (ii) locomotion experiments at different speeds. Interestingly, the timescales during BMI experiments did not change significantly with the control mode or training. During locomotion, the analysis identified units whose timescale varied consistently with the experimentally controlled speed of walking, though the specific timescale reflected also the recovery properties of the unit. Thus, the proposed method, SITA, characterizes the timescales of neural encoding and how they are affected by the motor task, while accounting for all rate modulations.

On equatorially symmetric and antisymmetric geomagnetic secular variation timescales

NASA Astrophysics Data System (ADS)

Amit, Hagay; Coutelier, Maélie; Christensen, Ulrich R.

2018-03-01

It has been suggested that the secular variation (SV) timescales of the geomagnetic field vary as 1 / ℓ (where ℓ is the spherical harmonic degree), except for the dipole. Here we propose that the same scaling law applies for SV timescales defined for different symmetry classes of the geomagnetic field and SV. We decompose the field and its SV into symmetric and antisymmetric parts and show in geomagnetic field models and numerical dynamo simulations that the corresponding SV timescales also vary as 1 / ℓ , again except for the dipole. The time-average antisymmetric/symmetric SV timescales are larger/smaller than the total, respectively. The difference in SV timescales between these two symmetry classes is probably due to different degrees of alignment of the core flow with different magnetic field structures at the core-mantle boundary. The symmetric dipole SV timescale in the recent geomagnetic field and in long-term time-averages from numerical dynamos is below the extrapolated 1 / ℓ curve, whereas before ∼ 1965 the geomagnetic dipole tilt was rather steady and the symmetric dipole SV timescale exceeded the extrapolated 1 / ℓ curve. We hypothesize that the period of nearly steady geomagnetic dipole tilt between 1810-1965 was anomalous for the geodynamo. Overall, the deviation of the dipole SV timescales from the 1 / ℓ curves may indicate that magnetic diffusion contributes to the dipole SV more than it does for higher degrees.

A Flexible Parameterization for Shortwave Optical Properties of Ice Crystals

NASA Technical Reports Server (NTRS)

VanDiedenhoven, Bastiaan; Ackerman, Andrew S.; Cairns, Brian; Fridlind, Ann M.

2014-01-01

A parameterization is presented that provides extinction cross section sigma (sub e), single-scattering albedo omega, and asymmetry parameter (g) of ice crystals for any combination of volume, projected area, aspect ratio, and crystal distortion at any wavelength in the shortwave. Similar to previous parameterizations, the scheme makes use of geometric optics approximations and the observation that optical properties of complex, aggregated ice crystals can be well approximated by those of single hexagonal crystals with varying size, aspect ratio, and distortion levels. In the standard geometric optics implementation used here, sigma (sub e) is always twice the particle projected area. It is shown that omega is largely determined by the newly defined absorption size parameter and the particle aspect ratio. These dependences are parameterized using a combination of exponential, lognormal, and polynomial functions. The variation of (g) with aspect ratio and crystal distortion is parameterized for one reference wavelength using a combination of several polynomials. The dependences of g on refractive index and omega are investigated and factors are determined to scale the parameterized (g) to provide values appropriate for other wavelengths. The parameterization scheme consists of only 88 coefficients. The scheme is tested for a large variety of hexagonal crystals in several wavelength bands from 0.2 to 4 micron, revealing absolute differences with reference calculations of omega and (g) that are both generally below 0.015. Over a large variety of cloud conditions, the resulting root-mean-squared differences with reference calculations of cloud reflectance, transmittance, and absorptance are 1.4%, 1.1%, and 3.4%, respectively. Some practical applications of the parameterization in atmospheric models are highlighted.

Domain-averaged snow depth over complex terrain from flat field measurements

NASA Astrophysics Data System (ADS)

Helbig, Nora; van Herwijnen, Alec

2017-04-01

Snow depth is an important parameter for a variety of coarse-scale models and applications, such as hydrological forecasting. Since high-resolution snow cover models are computational expensive, simplified snow models are often used. Ground measured snow depth at single stations provide a chance for snow depth data assimilation to improve coarse-scale model forecasts. Snow depth is however commonly recorded at so-called flat fields, often in large measurement networks. While these ground measurement networks provide a wealth of information, various studies questioned the representativity of such flat field snow depth measurements for the surrounding topography. We developed two parameterizations to compute domain-averaged snow depth for coarse model grid cells over complex topography using easy to derive topographic parameters. To derive the two parameterizations we performed a scale dependent analysis for domain sizes ranging from 50m to 3km using highly-resolved snow depth maps at the peak of winter from two distinct climatic regions in Switzerland and in the Spanish Pyrenees. The first, simpler parameterization uses a commonly applied linear lapse rate. For the second parameterization, we first removed the obvious elevation gradient in mean snow depth, which revealed an additional correlation with the subgrid sky view factor. We evaluated domain-averaged snow depth derived with both parameterizations using flat field measurements nearby with the domain-averaged highly-resolved snow depth. This revealed an overall improved performance for the parameterization combining a power law elevation trend scaled with the subgrid parameterized sky view factor. We therefore suggest the parameterization could be used to assimilate flat field snow depth into coarse-scale snow model frameworks in order to improve coarse-scale snow depth estimates over complex topography.

Adaptive Equilibrium Regulation: A Balancing Act in Two Timescales

PubMed Central

Boker, Steven M.

2015-01-01

An equilibrium involves a balancing of forces. Just as one maintains upright posture in standing or walking, many self-regulatory and interpersonal behaviors can be framed as a balancing act between an ever changing environment and within-person processes. The emerging balance between person and environment, the equilibria, are dynamic and adaptive in response to development and learning. A distinction is made between equilibrium achieved solely due to a short timescale balancing of forces and a longer timescale preferred equilibrium which we define as a state towards which the system slowly adapts. Together, these are developed into a framework that this article calls Adaptive Equilibrium Regulation (ÆR), which separates a regulatory process into two timescales: a faster regulation that automatically balances forces and a slower timescale adaptation process that reconfigures the fast regulation so as to move the system towards its preferred equilibrium when an environmental force persists over the longer timescale. This way of thinking leads to novel models for the interplay between multiple timescales of behavior, learning, and development. PMID:27066197

Six-Degree-of-Freedom Trajectory Optimization Utilizing a Two-Timescale Collocation Architecture

NASA Technical Reports Server (NTRS)

Desai, Prasun N.; Conway, Bruce A.

2005-01-01

Six-degree-of-freedom (6DOF) trajectory optimization of a reentry vehicle is solved using a two-timescale collocation methodology. This class of 6DOF trajectory problems are characterized by two distinct timescales in their governing equations, where a subset of the states have high-frequency dynamics (the rotational equations of motion) while the remaining states (the translational equations of motion) vary comparatively slowly. With conventional collocation methods, the 6DOF problem size becomes extraordinarily large and difficult to solve. Utilizing the two-timescale collocation architecture, the problem size is reduced significantly. The converged solution shows a realistic landing profile and captures the appropriate high-frequency rotational dynamics. A large reduction in the overall problem size (by 55%) is attained with the two-timescale architecture as compared to the conventional single-timescale collocation method. Consequently, optimum 6DOF trajectory problems can now be solved efficiently using collocation, which was not previously possible for a system with two distinct timescales in the governing states.

Drawing from Memory: Hand-Eye Coordination at Multiple Scales

PubMed Central

Spivey, Michael J.

2013-01-01

Eyes move to gather visual information for the purpose of guiding behavior. This guidance takes the form of perceptual-motor interactions on short timescales for behaviors like locomotion and hand-eye coordination. More complex behaviors require perceptual-motor interactions on longer timescales mediated by memory, such as navigation, or designing and building artifacts. In the present study, the task of sketching images of natural scenes from memory was used to examine and compare perceptual-motor interactions on shorter and longer timescales. Eye and pen trajectories were found to be coordinated in time on shorter timescales during drawing, and also on longer timescales spanning study and drawing periods. The latter type of coordination was found by developing a purely spatial analysis that yielded measures of similarity between images, eye trajectories, and pen trajectories. These results challenge the notion that coordination only unfolds on short timescales. Rather, the task of drawing from memory evokes perceptual-motor encodings of visual images that preserve coarse-grained spatial information over relatively long timescales as well. PMID:23554894

Conditional dissipation of scalars in homogeneous turbulence: Closure for MMC modelling

NASA Astrophysics Data System (ADS)

Wandel, Andrew P.

2013-08-01

While the mean and unconditional variance are to be predicted well by any reasonable turbulent combustion model, these are generally not sufficient for the accurate modelling of complex phenomena such as extinction/reignition. An additional criterion has been recently introduced: accurate modelling of the dissipation timescales associated with fluctuations of scalars about their conditional mean (conditional dissipation timescales). Analysis of Direct Numerical Simulation (DNS) results for a passive scalar shows that the conditional dissipation timescale is of the order of the integral timescale and smaller than the unconditional dissipation timescale. A model is proposed: the conditional dissipation timescale is proportional to the integral timescale. This model is used in Multiple Mapping Conditioning (MMC) modelling for a passive scalar case and a reactive scalar case, comparing to DNS results for both. The results show that this model improves the accuracy of MMC predictions so as to match the DNS results more closely using a relatively-coarse spatial resolution compared to other turbulent combustion models.

Effects of hamstring stretching on passive muscle stiffness vary between hip flexion and knee extension maneuvers.

PubMed

Miyamoto, N; Hirata, K; Kanehisa, H

2017-01-01

The purpose of this study was to examine whether the effects of hamstring stretching on the passive stiffness of each of the long head of the biceps femoris (BFl), semitendinosus (ST), and semimembranosus (SM) vary between passive knee extension and hip flexion stretching maneuvers. In 12 male subjects, before and after five sets of 90 s static stretching, passive lengthening measurements where knee or hip joint was passively rotated to the maximal range of motion (ROM) were performed. During the passive lengthening, shear modulus of each muscle was measured by ultrasound shear wave elastography. Both stretching maneuvers significantly increased maximal ROM and decreased passive torque at a given joint angle. Passive knee extension stretching maneuver significantly reduced shear modulus at a given knee joint angle in all of BFl, ST, and SM. In contrast, the stretching effect by passive hip flexion maneuver was significant only in ST and SM. The present findings indicate that the effects of hamstring stretching on individual passive muscles' stiffness vary between passive knee extension and hip flexion stretching maneuvers. In terms of reducing the muscle stiffness of BFl, stretching of the hamstring should be performed by passive knee extension rather than hip flexion. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Influence of the stretch wrapping process on the mechanical behavior of a stretch film

NASA Astrophysics Data System (ADS)

Klein, Daniel; Stommel, Markus; Zimmer, Johannes

2018-05-01

Lightweight construction is an ongoing task in packaging development. Consequently, the stability of packages during transport is gaining importance. This study contributes to the optimization of lightweight packaging concepts regarding their stability. A very widespread packaging concept is the distribution of goods on a pallet whereas a Polyethylene (PE) stretch film stabilizes the lightweight structure during the shipment. Usually, a stretch wrapping machine applies this stretch film to the pallet. The objective of this study is to support packaging development with a method that predicts the result of the wrapping process, based on the mechanical characterization of the stretch film. This result is not only defined by the amount of stretch film, its spatial distribution on the pallet and its internal stresses that result in a containment force. More accurate, this contribution also considers the influence of the deformation history of the stretch film during the wrapping process. By focusing on similarities of stretch wrappers rather than on differences, the influence of generalized process parameters on stretch film mechanics and thereby on pallet stability can be determined experimentally. For a practical use, the predictive method is accumulated in an analytic model of the wrapping process that can be verified experimentally. This paves the way for experimental and numerical approaches regarding the optimization of pallet stability.

Parameterization of eddy sensible heat transports in a zonally averaged dynamic model of the atmosphere

NASA Technical Reports Server (NTRS)

Genthon, Christophe; Le Treut, Herve; Sadourny, Robert; Jouzel, Jean

1990-01-01

A Charney-Branscome based parameterization has been tested as a way of representing the eddy sensible heat transports missing in a zonally averaged dynamic model (ZADM) of the atmosphere. The ZADM used is a zonally averaged version of a general circulation model (GCM). The parameterized transports in the ZADM are gaged against the corresponding fluxes explicitly simulated in the GCM, using the same zonally averaged boundary conditions in both models. The Charney-Branscome approach neglects stationary eddies and transient barotropic disturbances and relies on a set of simplifying assumptions, including the linear appoximation, to describe growing transient baroclinic eddies. Nevertheless, fairly satisfactory results are obtained when the parameterization is performed interactively with the model. Compared with noninteractive tests, a very efficient restoring feedback effect between the modeled zonal-mean climate and the parameterized meridional eddy transport is identified.

Predictive Compensator Optimization for Head Tracking Lag in Virtual Environments

NASA Technical Reports Server (NTRS)

Adelstein, Barnard D.; Jung, Jae Y.; Ellis, Stephen R.

2001-01-01

We examined the perceptual impact of plant noise parameterization for Kalman Filter predictive compensation of time delays intrinsic to head tracked virtual environments (VEs). Subjects were tested in their ability to discriminate between the VE system's minimum latency and conditions in which artificially added latency was then predictively compensated back to the system minimum. Two head tracking predictors were parameterized off-line according to cost functions that minimized prediction errors in (1) rotation, and (2) rotation projected into translational displacement with emphasis on higher frequency human operator noise. These predictors were compared with a parameterization obtained from the VE literature for cost function (1). Results from 12 subjects showed that both parameterization type and amount of compensated latency affected discrimination. Analysis of the head motion used in the parameterizations and the subsequent discriminability results suggest that higher frequency predictor artifacts are contributory cues for discriminating the presence of predictive compensation.

Ankle-Dorsiflexion Range of Motion After Ankle Self-Stretching Using a Strap

PubMed Central

Jeon, In-cheol; Kwon, Oh-yun; Yi, Chung-Hwi; Cynn, Heon-Seock; Hwang, Ui-jae

2015-01-01

Context  A variety of ankle self-stretching exercises have been recommended to improve ankle-dorsiflexion range of motion (DFROM) in individuals with limited ankle dorsiflexion. A strap can be applied to stabilize the talus and facilitate anterior glide of the distal tibia at the talocrural joint during ankle self-stretching exercises. Novel ankle self-stretching using a strap (SSS) may be a useful method of improving ankle DFROM. Objective  To compare the effects of 2 ankle-stretching techniques (static stretching versus SSS) on ankle DFROM. Design  Randomized controlled clinical trial. Setting  University research laboratory. Patients or Other Participants  Thirty-two participants with limited active dorsiflexion (<20°) while sitting (14 women and 18 men) were recruited. Main Outcome Measure(s)  The participants performed 2 ankle self-stretching techniques (static stretching and SSS) for 3 weeks. Active DFROM (ADFROM), passive DFROM (PDFROM), and the lunge angle were measured. An independent t test was used to compare the improvements in these values before and after the 2 stretching interventions. The level of statistical significance was set at α = .05. Results  Active DFROM and PDFROM were greater in both stretching groups after the 3-week interventions. However, ADFROM, PDFROM, and the lunge angle were greater in the SSS group than in the static-stretching group (P < .05). Conclusions  Ankle SSS is recommended to improve ADFROM, PDFROM, and the lunge angle in individuals with limited DFROM. PMID:26633750

Adding dimension to cellular mechanotransduction: Advances in biomedical engineering of multiaxial cell-stretch systems and their application to cardiovascular biomechanics and mechano-signaling.

PubMed

Friedrich, O; Schneidereit, D; Nikolaev, Y A; Nikolova-Krstevski, V; Schürmann, S; Wirth-Hücking, A; Merten, A L; Fatkin, D; Martinac, B

2017-11-01

Hollow organs (e.g. heart) experience pressure-induced mechanical wall stress sensed by molecular mechano-biosensors, including mechanosensitive ion channels, to translate into intracellular signaling. For direct mechanistic studies, stretch devices to apply defined extensions to cells adhered to elastomeric membranes have stimulated mechanotransduction research. However, most engineered systems only exploit unilateral cellular stretch. In addition, it is often taken for granted that stretch applied by hardware translates 1:1 to the cell membrane. However, the latter crucially depends on the tightness of the cell-substrate junction by focal adhesion complexes and is often not calibrated for. In the heart, (increased) hemodynamic volume/pressure load is associated with (increased) multiaxial wall tension, stretching individual cardiomyocytes in multiple directions. To adequately study cellular models of chronic organ distension on a cellular level, biomedical engineering faces challenges to implement multiaxial cell stretch systems that allow observing cell reactions to stretch during live-cell imaging, and to calibrate for hardware-to-cell membrane stretch translation. Here, we review mechanotransduction, cell stretch technologies from uni-to multiaxial designs in cardio-vascular research, and the importance of the stretch substrate-cell membrane junction. We also present new results using our IsoStretcher to demonstrate mechanosensitivity of Piezo1 in HEK293 cells and stretch-induced Ca 2+ entry in 3D-hydrogel-embedded cardiomyocytes. Copyright © 2017 Elsevier Ltd. All rights reserved.

Acute Effects of Different Agonist and Antagonist Stretching Arrangements on Static and Dynamic Range of Motion

PubMed Central

Amiri-Khorasani, Mohammadtaghi; Kellis, Eleftherios

2015-01-01

Background: Traditionally, stretching exercises are considered as basic components of warm up aiming to prepare the musculoskeletal system for performance and to prevent injuries. Objectives: The purpose of this study was to examine the effects of different agonist and antagonist stretching arrangements within a pre-exercise warm-up on hip static (SROM) and dynamic range of motion (DROM). Materials and Methods: Sixty trained male subjects (Mean ± SD: height, 177.38 ± 6.92 cm; body mass, 68.4 ± 10.22 kg; age, 21.52 ± 1.17 years) volunteered to participate in this study. SROM was measured by V-sit test and DROM captured by a motion analysis system before and after (i) static stretching for both hip flexor and extensor muscles (SFSE), (ii) dynamic stretching for both hip flexor and extensor muscles (DFDE), (iii) static stretching for the hip flexors and dynamic stretching for hip extensors (SFDE), and (iv) dynamic stretching for the hip flexors and static stretching for hip extensors (DFSE). Results: DFSE showed a significantly higher increase in DROM and SROM than the remainder of the stretching protocols (P < 0.05). There were significant differences between DFDE with SFSE and SFDE (P < 0.05) and SFSE showed significant increase as compared to SFDE (P < 0.05). Conclusions: In conclusion, DFSE is probably the best stretching arrangement due to producing more post activation potentiation on agonist muscles and less muscle stiffness in antagonist muscles. PMID:26715975

[Effects of different mechanical stretch conditions on differentiation of rat tendon stem cells].

PubMed

Li, Pao; Gao, Shang; Zhou, Mei; Tang, Hong; Mu, Miduo; Zhang, Jiqiang; Tang, Kanglai

2017-04-01

To investigate the effects of different mechanical stretch conditions on the differentiation of rat tendon stem cells (TSCs), to find the best uniaxial cyclic stretching for TSCs tenogenic differentiation, osteogenic differentiation, and adipogenic differentiation. TSCs were isolated from the Achilles tendons of 8-week-old male Sprague Dawley rats by enzymatic digestion method and cultured. The TSCs at passage 3 were randomly divided into 5 groups: group A (stretch strength of 4% and frequency of 1 Hz), group B (stretch strength of 4% and frequency of 2 Hz), group C (stretch strength of 8% and frequency of 1 Hz), group D (stretch strength of 8% and frequency of 2 Hz), and group E (static culture). At 12, 24, and 48 hours after mechanical stretch, the mRNA expressions of the tenogenic differentiation related genes [Scleraxis (SCX) and Tenascin C (TNC)], the osteogenic differentiation related genes [runt related transcription factor 2 (RUNX2) and distal-less homeobox 5 (DLX5)], and the adipogenic differentiation related genes [CCAAT-enhancer-binding protein-α (CEBPα) and lipoprteinlipase (LPL)] were detected by real-time fluorescent quantitative PCR and the protein expressions of TNC, CEBPα, and RUNX2 were detected by Western blot. The mRNA expressions of SCX and TNC in group B were significantly higher than those in groups A, C, D, and E at 24 hours after mechanical stretch ( P <0.05). The mRNA expressions of CEBPα and LPL in group D were significantly higher than those in groups A, B, C, and E at 48 hours after mechanical stretch ( P <0.05). The mRNA expressions of RUNX2 and DLX5 in group C were significantly higher than those in groups A, B, D, and E at 24 hours after mechanical stretch ( P <0.05). Western blot detection showed that higher protein expression of TNC in group B than group E at each time point after mechanical stretch ( P <0.05), and the protein expression of CEBPα was significantly inhibited when compared with group E at 24 hours after mechanical stretch ( P <0.05). At 24 hours after mechanical stretch, the protein expression of RUNX2 in group C was significantly higher than that in group E ( P <0.05); and the protein expression of TNC was significantly lower than that in group E at 24 and 48 hours after mechanical stretch ( P <0.05). At 48 hours after mechanical stretch, the protein expression of CEBPα was significantly increased and the protein expression of TNC was significantly decreased in group D when compared with group E ( P <0.05), but no significant difference was found in the protein expression of RUNX2 between groups D and E ( P >0.05). The mechanical strain could promote differentiation of TSCs, and different parameter of stretch will lead to different differentiation. The best stretch condition for tenogenic differentiation is 4% strength and 2 Hz frequency for 24 hours; the best stretch condition for osteogenic differentiation is 8% strength and 1 Hz frequency for 24 hours; and the best stretch condition for adipogenic differentiation is 8% strength and 2 Hz frequency for 48 hours.

Stretching Reduces Skin Thickness and Improves Subcutaneous Tissue Mobility in a Murine Model of Systemic Sclerosis.

PubMed

Xiong, Ying; Berrueta, Lisbeth; Urso, Katia; Olenich, Sara; Muskaj, Igla; Badger, Gary J; Aliprantis, Antonios; Lafyatis, Robert; Langevin, Helene M

2017-01-01

Although physical therapy can help preserve mobility in patients with systemic sclerosis (SSc), stretching has not been used systematically as a treatment to prevent or reverse the disease process. We previously showed in rodent models that stretching promotes the resolution of connective tissue inflammation and reduces new collagen formation after injury. Here, we tested the hypothesis that stretching would impact scleroderma development using a mouse sclerodermatous graft-versus-host disease (sclGvHD) model. The model consists in the adoptive transfer (allogeneic) of splenocytes from B10.D2 mice (graft) into Rag2 -/- BALB/c hosts (sclGvHD), resulting in skin inflammation followed by fibrosis over 4 weeks. SclGvHD mice and controls were randomized to stretching in vivo for 10 min daily versus no stretching. Weekly ultrasound measurements of skin thickness and subcutaneous tissue mobility in the back (relative tissue displacement during passive trunk motion) successfully captured the different phases of the sclGvHD model. Stretching reduced skin thickness and increased subcutaneous tissue mobility compared to no stretching at week 3. Stretching also reduced the expression of CCL2 and ADAM8 in the skin at week 4, which are two genes known to be upregulated in both murine sclGvHD and the inflammatory subset of human SSc. However, there was no evidence that stretching attenuated inflammation at week 2. Daily stretching for 10 min can improve skin thickness and mobility in the absence of any other treatment in the sclGvHD murine model. These pre-clinical results suggest that a systematic investigation of stretching as a therapeutic modality is warranted in patients with SSc.

Postactivation potentiation can counteract declines in force and power that occur after stretching.

PubMed

Kümmel, J; Kramer, A; Cronin, N J; Gruber, M

2017-12-01

Stretching can decrease a muscle's maximal force, whereas short but intense muscle contractions can increase it. We hypothesized that when combined, postactivation potentiation induced by reactive jumps would counteract stretch-induced decrements in drop jump (DJ) performance. Moreover, we measured changes in muscle twitch forces and ankle joint stiffness (K A nkle ) to examine underlying mechanisms. Twenty subjects completed three DJs and 10 electrically evoked muscle twitches of the triceps surae subsequent to four different conditioning activities and control. The conditioning activities were 10 hops, 20s of static stretching of the triceps surae muscle, 20s of stretching followed by 10 hops, and vice versa. After 10 hops, twitch peak torque (TPT) was 20% and jump height 5% higher compared with control with no differences in K A nkle . After stretching, TPT and jump height were both 9% and K A nkle 6% lower. When hops and stretching were combined as conditioning activities, jump height was not different compared with control but significantly higher (11% and 8%) compared with stretching. TPTs were 16% higher compared with control when the hops were performed after stretching and 9% higher compared with the reverse order. K A nkle was significantly lower when stretching was performed after the hops (6%) compared with control, but no significant difference was observed when hops were performed after stretching. These results demonstrate that conditioning hops can counteract stretch-related declines in DJ performance. Furthermore, the differences in TPTs and K A nkle between combined conditioning protocols indicate that the order of conditioning tasks might play an important role at the muscle-tendon level. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Muramyl Peptide-Enhanced Sleep: Pharmacological Optimization of Performance

DTIC Science & Technology

1988-06-01

drinking). In addition, each occur- rence of stretching /yawning ( stretching or yawning separately or the combina- tion oi both) and sexual excitation... Stretching /yawning was observed most frequ3ntly 11-20 min after adminis- tration of aMSH (Fig. 17 A, C: cumulative number of episodes). Stretching / yawning...occurred with a mean frequency of one episode per rabbit during the 1-h observation period after ICV injection of aCSF. The number of stretching

Cross section parameterizations for cosmic ray nuclei. 1: Single nucleon removal

NASA Technical Reports Server (NTRS)

Norbury, John W.; Townsend, Lawrence W.

1992-01-01

Parameterizations of single nucleon removal from electromagnetic and strong interactions of cosmic rays with nuclei are presented. These parameterizations are based upon the most accurate theoretical calculations available to date. They should be very suitable for use in cosmic ray propagation through interstellar space, the Earth's atmosphere, lunar samples, meteorites, spacecraft walls and lunar and martian habitats.

Improvement of the GEOS-5 AGCM upon Updating the Air-Sea Roughness Parameterization

NASA Technical Reports Server (NTRS)

Garfinkel, C. I.; Molod, A.; Oman, L. D.; Song, I.-S.

2011-01-01

The impact of an air-sea roughness parameterization over the ocean that more closely matches recent observations of air-sea exchange is examined in the NASA Goddard Earth Observing System, version 5 (GEOS-5) atmospheric general circulation model. Surface wind biases in the GEOS-5 AGCM are decreased by up to 1.2m/s. The new parameterization also has implications aloft as improvements extend into the stratosphere. Many other GCMs (both for operational weather forecasting and climate) use a similar class of parameterization for their air-sea roughness scheme. We therefore expect that results from GEOS-5 are relevant to other models as well.

Observational and Modeling Studies of Clouds and the Hydrological Cycle

NASA Technical Reports Server (NTRS)

Somerville, Richard C. J.

1997-01-01

Our approach involved validating parameterizations directly against measurements from field programs, and using this validation to tune existing parameterizations and to guide the development of new ones. We have used a single-column model (SCM) to make the link between observations and parameterizations of clouds, including explicit cloud microphysics (e.g., prognostic cloud liquid water used to determine cloud radiative properties). Surface and satellite radiation measurements were used to provide an initial evaluation of the performance of the different parameterizations. The results of this evaluation will then used to develop improved cloud and cloud-radiation schemes, which were tested in GCM experiments.

Structural and parameteric uncertainty quantification in cloud microphysics parameterization schemes

NASA Astrophysics Data System (ADS)

van Lier-Walqui, M.; Morrison, H.; Kumjian, M. R.; Prat, O. P.; Martinkus, C.

2017-12-01

Atmospheric model parameterization schemes employ approximations to represent the effects of unresolved processes. These approximations are a source of error in forecasts, caused in part by considerable uncertainty about the optimal value of parameters within each scheme -- parameteric uncertainty. Furthermore, there is uncertainty regarding the best choice of the overarching structure of the parameterization scheme -- structrual uncertainty. Parameter estimation can constrain the first, but may struggle with the second because structural choices are typically discrete. We address this problem in the context of cloud microphysics parameterization schemes by creating a flexible framework wherein structural and parametric uncertainties can be simultaneously constrained. Our scheme makes no assuptions about drop size distribution shape or the functional form of parametrized process rate terms. Instead, these uncertainties are constrained by observations using a Markov Chain Monte Carlo sampler within a Bayesian inference framework. Our scheme, the Bayesian Observationally-constrained Statistical-physical Scheme (BOSS), has flexibility to predict various sets of prognostic drop size distribution moments as well as varying complexity of process rate formulations. We compare idealized probabilistic forecasts from versions of BOSS with varying levels of structural complexity. This work has applications in ensemble forecasts with model physics uncertainty, data assimilation, and cloud microphysics process studies.

Evaluating and Improving Wind Forecasts over South China: The Role of Orographic Parameterization in the GRAPES Model

NASA Astrophysics Data System (ADS)

Zhong, Shuixin; Chen, Zitong; Xu, Daosheng; Zhang, Yanxia

2018-06-01

Unresolved small-scale orographic (SSO) drags are parameterized in a regional model based on the Global/Regional Assimilation and Prediction System for the Tropical Mesoscale Model (GRAPES TMM). The SSO drags are represented by adding a sink term in the momentum equations. The maximum height of the mountain within the grid box is adopted in the SSO parameterization (SSOP) scheme as compensation for the drag. The effects of the unresolved topography are parameterized as the feedbacks to the momentum tendencies on the first model level in planetary boundary layer (PBL) parameterization. The SSOP scheme has been implemented and coupled with the PBL parameterization scheme within the model physics package. A monthly simulation is designed to examine the performance of the SSOP scheme over the complex terrain areas located in the southwest of Guangdong. The verification results show that the surface wind speed bias has been much alleviated by adopting the SSOP scheme, in addition to reduction of the wind bias in the lower troposphere. The target verification over Xinyi shows that the simulations with the SSOP scheme provide improved wind estimation over the complex regions in the southwest of Guangdong.

The zonally averaged transport characteristics of the atmosphere as determined by a general circulation model

NASA Technical Reports Server (NTRS)

Plumb, R. A.

1985-01-01

Two dimensional modeling has become an established technique for the simulation of the global structure of trace constituents. Such models are simpler to formulate and cheaper to operate than three dimensional general circulation models, while avoiding some of the gross simplifications of one dimensional models. Nevertheless, the parameterization of eddy fluxes required in a 2-D model is not a trivial problem. This fact has apparently led some to interpret the shortcomings of existing 2-D models as indicating that the parameterization procedure is wrong in principle. There are grounds to believe that these shortcomings result primarily from incorrect implementations of the predictions of eddy transport theory and that a properly based parameterization may provide a good basis for atmospheric modeling. The existence of these GCM-derived coefficients affords an unprecedented opportunity to test the validity of the flux-gradient parameterization. To this end, a zonally averaged (2-D) model was developed, using these coefficients in the transport parameterization. Results from this model for a number of contrived tracer experiments were compared with the parent GCM. The generally good agreement substantially validates the flus-gradient parameterization, and thus the basic principle of 2-D modeling.

A statistical comparison of cirrus particle size distributions measured using the 2-D stereo probe during the TC4, SPARTICUS, and MACPEX flight campaigns with historical cirrus datasets

NASA Astrophysics Data System (ADS)

Schwartz, M. Christian

2017-08-01

This paper addresses two straightforward questions. First, how similar are the statistics of cirrus particle size distribution (PSD) datasets collected using the Two-Dimensional Stereo (2D-S) probe to cirrus PSD datasets collected using older Particle Measuring Systems (PMS) 2-D Cloud (2DC) and 2-D Precipitation (2DP) probes? Second, how similar are the datasets when shatter-correcting post-processing is applied to the 2DC datasets? To answer these questions, a database of measured and parameterized cirrus PSDs - constructed from measurements taken during the Small Particles in Cirrus (SPARTICUS); Mid-latitude Airborne Cirrus Properties Experiment (MACPEX); and Tropical Composition, Cloud, and Climate Coupling (TC4) flight campaigns - is used.Bulk cloud quantities are computed from the 2D-S database in three ways: first, directly from the 2D-S data; second, by applying the 2D-S data to ice PSD parameterizations developed using sets of cirrus measurements collected using the older PMS probes; and third, by applying the 2D-S data to a similar parameterization developed using the 2D-S data themselves. This is done so that measurements of the same cloud volumes by parameterized versions of the 2DC and 2D-S can be compared with one another. It is thereby seen - given the same cloud field and given the same assumptions concerning ice crystal cross-sectional area, density, and radar cross section - that the parameterized 2D-S and the parameterized 2DC predict similar distributions of inferred shortwave extinction coefficient, ice water content, and 94 GHz radar reflectivity. However, the parameterization of the 2DC based on uncorrected data predicts a statistically significantly higher number of total ice crystals and a larger ratio of small ice crystals to large ice crystals than does the parameterized 2D-S. The 2DC parameterization based on shatter-corrected data also predicts statistically different numbers of ice crystals than does the parameterized 2D-S, but the comparison between the two is nevertheless more favorable. It is concluded that the older datasets continue to be useful for scientific purposes, with certain caveats, and that continuing field investigations of cirrus with more modern probes is desirable.

Evaluation of five dry particle deposition parameterizations for incorporation into atmospheric transport models

NASA Astrophysics Data System (ADS)

Khan, Tanvir R.; Perlinger, Judith A.

2017-10-01

Despite considerable effort to develop mechanistic dry particle deposition parameterizations for atmospheric transport models, current knowledge has been inadequate to propose quantitative measures of the relative performance of available parameterizations. In this study, we evaluated the performance of five dry particle deposition parameterizations developed by Zhang et al. (2001) (Z01), Petroff and Zhang (2010) (PZ10), Kouznetsov and Sofiev (2012) (KS12), Zhang and He (2014) (ZH14), and Zhang and Shao (2014) (ZS14), respectively. The evaluation was performed in three dimensions: model ability to reproduce observed deposition velocities, Vd (accuracy); the influence of imprecision in input parameter values on the modeled Vd (uncertainty); and identification of the most influential parameter(s) (sensitivity). The accuracy of the modeled Vd was evaluated using observations obtained from five land use categories (LUCs): grass, coniferous and deciduous forests, natural water, and ice/snow. To ascertain the uncertainty in modeled Vd, and quantify the influence of imprecision in key model input parameters, a Monte Carlo uncertainty analysis was performed. The Sobol' sensitivity analysis was conducted with the objective to determine the parameter ranking from the most to the least influential. Comparing the normalized mean bias factors (indicators of accuracy), we find that the ZH14 parameterization is the most accurate for all LUCs except for coniferous forest, for which it is second most accurate. From Monte Carlo simulations, the estimated mean normalized uncertainties in the modeled Vd obtained for seven particle sizes (ranging from 0.005 to 2.5 µm) for the five LUCs are 17, 12, 13, 16, and 27 % for the Z01, PZ10, KS12, ZH14, and ZS14 parameterizations, respectively. From the Sobol' sensitivity results, we suggest that the parameter rankings vary by particle size and LUC for a given parameterization. Overall, for dp = 0.001 to 1.0 µm, friction velocity was one of the three most influential parameters in all parameterizations. For giant particles (dp = 10 µm), relative humidity was the most influential parameter. Because it is the least complex of the five parameterizations, and it has the greatest accuracy and least uncertainty, we propose that the ZH14 parameterization is currently superior for incorporation into atmospheric transport models.

Effects of Cyclic Mechanical Stretch on the Proliferation of L6 Myoblasts and Its Mechanisms: PI3K/Akt and MAPK Signal Pathways Regulated by IGF-1 Receptor.

PubMed

Fu, Shaoting; Yin, Lijun; Lin, Xiaojing; Lu, Jianqiang; Wang, Xiaohui

2018-06-02

Myoblast proliferation is crucial to skeletal muscle hypertrophy and regeneration. Our previous study indicated that mechanical stretch altered the proliferation of C2C12 myoblasts, associated with insulin growth factor 1 (IGF-1)-mediated phosphoinositide 3-kinase (PI3K)/Akt (also known as protein kinase B) and mitogen-activated protein kinase (MAPK) pathways through IGF-1 receptor (IGF-1R). The purpose of this study was to explore the same stretches on the proliferation of L6 myoblasts and its association with IGF-1-regulated PI3K/Akt and MAPK activations. L6 myoblasts were divided into three groups: control, 15% stretch, and 20% stretch. Stretches were achieved using FlexCell Strain Unit. Cell proliferation and IGF-1 concentration were detected by CCK8 and ELISA, respectively. IGF-1R expression, and expressions and activities of PI3K, Akt, and MAPKs (including extracellular signal-regulated kinases 1 and 2 (ERK1/2) and p38) were determined by Western blot. We found that 15% stretch promoted, while 20% stretch inhibited L6 myoblast proliferation. A 15% stretch increased IGF-1R level, although had no effect on IGF-1 secretion of L6 myoblasts, and PI3K/Akt and ERK1/2 (not p38) inhibitors attenuated 15% stretch-induced pro-proliferation. Exogenous IGF-1 reversed 20% stretch-induced anti-proliferation, accompanied with increases in IGF-1R level as well as PI3K/Akt and MAPK (ERK1/2 and p38) activations. In conclusion, stretch regulated L6 myoblasts proliferation, which may be mediated by the changes in PI3K/Akt and MAPK activations regulated by IGF-1R, despite no detectable IGF-1 from stretched L6 myoblasts.

Acute Effects of Static vs. Ballistic Stretching on Strength and Muscular Fatigue Between Ballet Dancers and Resistance-Trained Women.

PubMed

Lima, Camila D; Brown, Lee E; Wong, Megan A; Leyva, Whitney D; Pinto, Ronei S; Cadore, Eduardo L; Ruas, Cassio V

2016-11-01

Lima, CD, Brown, LE, Wong, MA, Leyva, WD, Pinto, RS, Cadore, EL, and Ruas, CV. Acute effects of static vs. ballistic stretching on strength and muscular fatigue between ballet dancers and resistance-trained women. J Strength Cond Res 30(11): 3220-3227, 2016-Stretching is used to increase joint range of motion, but the acute effects can decrease muscle strength. However, this may depend on the population or mode of stretching. The purpose of this study was to compare the acute effects of static vs. ballistic stretching on strength and muscular fatigue between ballet dancers and resistance-trained women. Fifteen resistance-trained women (age 23.8 ± 1.80 years, mass 67.47 ± 7.77 kg, height 168.30 ± 5.53 cm) and 12 ballet dancers (age 22.8 ± 3.04 years, mass 58.67 ± 5.65 kg, height 168.00 ± 7.69 cm) performed 5 days of testing. The first day was control (no stretching), whereas the other 4 days were static or ballistic stretching in a counterbalanced order. Range of motion, strength, and fatigue tests were also performed. Both groups demonstrated a significant decrease in hamstrings strength after static (102.71 ± 2.67 N·m) and ballistic stretching (99.49 ± 2.61 N·m) compared with control (113.059 ± 3.25 N·m), with no changes in quadriceps strength. For fatigue, only ballet dancers demonstrated a decrease from control (71.79 ± 4.88%) to ballistic (65.65 ± 8.19%), but no difference with static (65.01 ± 12.29%). These findings suggest that stretching decreases hamstrings strength similarly in ballet dancers and resistance-trained women, with no differences between modes of stretching. However, ballistic stretching only decreased muscular fatigue in ballet dancers, but not in resistance-trained women. Therefore, no stretching should be performed before strength performance. However, ballistic stretching may decrease acute muscular fatigue in ballet dancers.

Acute Effects of the Different Intensity of Static Stretching on Flexibility and Isometric Muscle Force.

PubMed

Kataura, Satoshi; Suzuki, Shigeyuki; Matsuo, Shingo; Hatano, Genki; Iwata, Masahiro; Yokoi, Kazuaki; Tsuchida, Wakako; Banno, Yasuhiro; Asai, Yuji

2017-12-01

Kataura, S, Suzuki, S, Matsuo, S, Hatano, G, Iwata, M, Yokoi, K, Tsuchida, W, Banno, Y, and Asai, Y. Acute effects of the different intensity of static stretching on flexibility and isometric muscle force. J Strength Cond Res 31(12): 3403-3410, 2017-In various fields, static stretching is commonly performed to improve flexibility, whereas the acute effects of different stretch intensities are unclear. Therefore, we investigated the acute effects of different stretch intensities on flexibility and muscle force. Eighteen healthy participants (9 men and 9 women) performed 180-second static stretches of the right hamstrings at 80, 100, and 120% of maximum tolerable intensity without stretching pain, in random order. The following outcomes were assessed as markers of lower limb function and flexibility: static passive torque (SPT), range of motion (ROM), passive joint (muscle-tendon) stiffness, passive torque (PT) at onset of pain, and isometric muscle force. Static passive torque was significantly decreased after all stretching intensities (p ≤ 0.05). Compared with before stretching at 100 and 120% intensities, ROM and PT were significantly increased after stretching (p ≤ 0.05), and passive stiffness (p = 0.05) and isometric muscle force (p ≤ 0.05) were significantly decreased. In addition, ROM was significantly greater after stretching at 100 and 120% than at 80%, and passive stiffness was significantly lower after 120% than after 80% (p ≤ 0.05). However, all measurements except SPT were unchanged after 80% intensity. There was a weak positive correlation between the intensities of stretching and the relative change for SPT (p ≤ 0.05), a moderate positive correlation with ROM (p ≤ 0.05), and a moderate positive correlation with passive stiffness (p ≤ 0.05). These results indicate that static stretching at greater intensity is more effective for increasing ROM and decreasing passive muscle-tendon stiffness.

Porous poly(L-lactic acid) sheet prepared by stretching with starch particles as filler for tissue engineering.

PubMed

Ju, Dandan; Han, Lijing; Li, Zonglin; Chen, Yunjing; Wang, Qingjiang; Bian, Junjia; Dong, Lisong

2016-05-20

Porous poly(L-lactic acid) (PLLA) sheets were prepared by uniaxial stretching PLLA sheets containing starch filler. Here, the starch filler content, stretching ratio, stretching rate and stretching temperature are important factors to influence the structure of the porous PLLA sheets, therefore, they have been investigated in detail. The pore size distribution and tortuosity were characterized by Mercury Intrusion Porosimetry. The results revealed that the porosity and pore size enlarged with the increase of the starch filler content and stretching ratio, while shrank with the rise of stretching temperature. On the other hand, the pore structure almost had no changes with the stretching rate ranging between 5 and 40 mm/min. In order to test and verify that the porous PLLA sheet was suitable for the tissue engineering, the starch particles were removed by selective enzymatic degradation and its in vitro biocompatibility to osteoblast-like MC3T3-E1 cells was investigated. Copyright © 2016 Elsevier Ltd. All rights reserved.

Cyclic stretching of soft substrates induces spreading and growth

PubMed Central

Cui, Yidan; Hameed, Feroz M.; Yang, Bo; Lee, Kyunghee; Pan, Catherine Qiurong; Park, Sungsu; Sheetz, Michael

2015-01-01

In the body, soft tissues often undergo cycles of stretching and relaxation that may affect cell behaviour without changing matrix rigidity. To determine whether transient forces can substitute for a rigid matrix, we stretched soft pillar arrays. Surprisingly, 1–5% cyclic stretching over a frequency range of 0.01–10 Hz caused spreading and stress fibre formation (optimum 0.1 Hz) that persisted after 4 h of stretching. Similarly, stretching increased cell growth rates on soft pillars comparative to rigid substrates. Of possible factors linked to fibroblast growth, MRTF-A (myocardin-related transcription factor-A) moved to the nucleus in 2 h of cyclic stretching and reversed on cessation; but YAP (Yes-associated protein) moved much later. Knockdown of either MRTF-A or YAP blocked stretch-dependent growth. Thus, we suggest that the repeated pulling from a soft matrix can substitute for a stiff matrix in stimulating spreading, stress fibre formation and growth. PMID:25704457

Role of androgen receptor on cyclic mechanical stretch-regulated proliferation of C2C12 myoblasts and its upstream signals: IGF-1-mediated PI3K/Akt and MAPKs pathways.

PubMed

Ma, Yiming; Fu, Shaoting; Lu, Lin; Wang, Xiaohui

2017-07-15

To detect the effects of androgen receptor (AR) on cyclic mechanical stretch-modulated proliferation of C2C12 myoblasts and its pathways: roles of IGF-1, PI3K and MAPK. C2C12 were randomly divided into five groups: un-stretched control, six or 8 h of fifteen percent stretch, and six or 8 h of twenty percent stretch. Cyclic mechanical stretch of C2C12 were completed using a computer-controlled FlexCell Strain Unit. Cell proliferation and IGF-1 concentration in medium were detected by CCK8 and ELISA, respectively. Expressions of AR and IGF-1R, and expressions and activities of PI3K, p38 and ERK1/2 in stretched C2C12 cells were determined by Western blot. ①The proliferation of C2C12 cells, IGF-1 concentration in medium, expressions of AR and IGF-1R, and activities of PI3K, p38 and ERK1/2 were increased by 6 h of fifteen percent stretch, while decreased by twenty percent stretch for six or 8 h ②The fifteen percent stretch-increased proliferation of C2C12 cells was reversed by AR inhibitor, Flutamide. ③The increases of AR expression, activities of PI3K, p38 and ERK1/2 resulted from fifteen percent stretch were attenuated by IGF-1 neutralizing antibody, while twenty percent stretch-induced decreases of the above indicators were enhanced by recombinant IGF-1. ④Specific inhibitors of p38, ERK1/2 and PI3K all decreased the expression of AR in fifteen percent and twenty percent of stretched C2C12 cells. Cyclic mechanical stretch modulated the proliferation of C2C12 cells, which may be attributed to the alterations of AR via IGF-1-PI3K/Akt and IGF-1-MAPK (p38, ERK1/2) pathways in C2C12 cells. Copyright © 2017 Elsevier B.V. All rights reserved.

Amount of torque and duration of stretching affects correction of knee contracture in a rat model of spinal cord injury.

PubMed

Moriyama, Hideki; Tobimatsu, Yoshiko; Ozawa, Junya; Kito, Nobuhiro; Tanaka, Ryo

2013-11-01

Joint contractures are a common complication of many neurologic conditions, and stretching often is advocated to prevent and treat these contractures. However, the magnitude and duration of the stretching done in practice usually are guided by subjective clinical impressions. Using an established T8 spinal cord injury rat model of knee contracture, we sought to determine what combination of static or intermittent stretching, varied by magnitude (high or low) and duration (long or short), leads to the best (1) improvement in the limitation in ROM; (2) restoration of the muscular and articular factors leading to contractures; and (3) prevention and treatment of contracture-associated histologic alterations of joint capsule and articular cartilage. Using a rat animal model, the spinal cord was transected completely at the level of T8. The rats were randomly assigned to seven treatment groups (n = 4 per group), which were composed of static or intermittent stretching in combination with different amounts of applied torque magnitude and duration. We assessed the effect of stretching by measuring the ROM and evaluating the histologic alteration of the capsule and cartilage. Contractures improved in all treated groups except for the low-torque and short-duration static stretching conditions. High-torque stretching was effective against shortening of the synovial membrane and adhesions in the posterosuperior regions. Collagen Type II and VEGF in the cartilage were increased by stretching. High-torque and long-duration static stretching led to greater restoration of ROM than the other torque and duration treatment groups. Stretching was more effective in improving articular components of contractures compared with the muscular components. Stretching in this rat model prevented shortening and adhesion of the joint capsule, and affected biochemical composition, but did not change morphologic features of the cartilage. This animal study tends to support the ideas that static stretching can influence joint ROM and histologic qualities of joint tissues, and that the way stretching is performed influences its efficacy. However, further studies are warranted to determine if our findings are clinically applicable.

The Analytical Limits of Modeling Short Diffusion Timescales

NASA Astrophysics Data System (ADS)

Bradshaw, R. W.; Kent, A. J.

2016-12-01

Chemical and isotopic zoning in minerals is widely used to constrain the timescales of magmatic processes such as magma mixing and crystal residence, etc. via diffusion modeling. Forward modeling of diffusion relies on fitting diffusion profiles to measured compositional gradients. However, an individual measurement is essentially an average composition for a segment of the gradient defined by the spatial resolution of the analysis. Thus there is the potential for the analytical spatial resolution to limit the timescales that can be determined for an element of given diffusivity, particularly where the scale of the gradient approaches that of the measurement. Here we use a probabilistic modeling approach to investigate the effect of analytical spatial resolution on estimated timescales from diffusion modeling. Our method investigates how accurately the age of a synthetic diffusion profile can be obtained by modeling an "unknown" profile derived from discrete sampling of the synthetic compositional gradient at a given spatial resolution. We also include the effects of analytical uncertainty and the position of measurements relative to the diffusion gradient. We apply this method to the spatial resolutions of common microanalytical techniques (LA-ICP-MS, SIMS, EMP, NanoSIMS). Our results confirm that for a given diffusivity, higher spatial resolution gives access to shorter timescales, and that each analytical spacing has a minimum timescale, below which it overestimates the timescale. For example, for Ba diffusion in plagioclase at 750 °C timescales are accurate (within 20%) above 10, 100, 2,600, and 71,000 years at 0.3, 1, 5, and 25 mm spatial resolution, respectively. For Sr diffusion in plagioclase at 750 °C, timescales are accurate above 0.02, 0.2, 4, and 120 years at the same spatial resolutions. Our results highlight the importance of selecting appropriate analytical techniques to estimate accurate diffusion-based timescales.

Formation of Highly Aligned Collagen Nanofibers by Continuous Cyclic Stretch of a Collagen Hydrogel Sheet.

PubMed

Nam, Eunryel; Lee, Won Chul; Takeuchi, Shoji

2016-07-01

A collagen sheet with highly aligned collagen fibers is fabricated by continuous cyclic stretch. The rearrangement of the collagen fibers depends on the different process parameters of the cyclic stretch, including magnitude, frequency, and period of stretch. The collagen fibers are aligned perpendicularly to the direction of the stretch. Corneal stromal cells and smooth muscle cells cultivated on the highly aligned collagen sheet show alignment along the collagen fibers without the stretch during culture. Thus, the sheet can be a suitable scaffold for use in regenerative medicine. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

The Acute Effects of Upper Extremity Stretching on Throwing Velocity in Baseball Throwers

PubMed Central

Melton, Jason; Delobel, Ashley; Puentedura, Emilio J.

2013-01-01

Purpose. To examine the effects of static and proprioceptive neuromuscular facilitation (PNF) stretching of the shoulder internal rotators on throwing velocity. Subjects. 27 male throwers (mean age = 25.1 years old, SD = 2.4) with adequate knowledge of demonstrable throwing mechanics. Study Design. Randomized crossover trial with repeated measures. Methods. Subjects warmed up, threw 10 pitches at their maximum velocity, were randomly assigned to 1 of 3 stretching protocols (static, PNF, or no stretch), and then repeated their 10 pitches. Velocities were recorded after each pitch and average and peak velocities were recorded after each session. Results. Data were analyzed using a 3 × 2 repeated measures ANOVA. No significant interaction between stretching and throwing velocity was observed. Main effects for time were not statistically significant. Main effects for the stretching groups were statistically significant. Discussion. Results suggest that stretching of the shoulder internal rotators did not significantly affect throwing velocity immediately after stretching. This may be due to the complexity of the throwing task. Conclusions. Stretching may be included in a thrower's warm-up without any effects on throwing velocity. Further research should be performed using a population with more throwing experience and skill. PMID:26464880

Effects of high-intensity pulse irradiation with linear polarized near-infrared rays and stretching on muscle tone in patients with cerebrovascular disease: a randomized controlled trial.

PubMed

Takeuchi, Nobuyuki; Takezako, Nobuhiro; Shimonishi, Yuko; Usuda, Shigeru

2017-08-01

[Purpose] The purpose of this study was to clarify the influence of high-intensity pulse irradiation with linear polarized near-infrared rays (HI-LPNR) and stretching on hypertonia in cerebrovascular disease patients. [Subjects and Methods] The subjects were 40 cerebrovascular disease patients with hypertonia of the ankle joint plantar flexor muscle. The subjects were randomly allocated to groups undergoing treatment with HI-LPNR irradiation (HI-LPNR group), stretching (stretching group), HI-LPNR irradiation followed by stretching (combination group), and control group (10 subjects each). In all groups, the passive range of motion of ankle dorsiflexion and passive resistive joint torque of ankle dorsiflexion were measured before and after the specified intervention. [Results] The changes in passive range of motion, significant increase in the stretching and combination groups compared with that in the control group. The changes in passive resistive joint torque, significant decrease in HI-LPNR, stretching, and combination groups compared with that in the control group. [Conclusion] HI-LPNR irradiation and stretching has effect of decrease muscle tone. However, combination of HI-LPNR irradiation and stretching has no multiplier effect.

Sequence-length variation of mtDNA HVS-I C-stretch in Chinese ethnic groups.

PubMed

Chen, Feng; Dang, Yong-hui; Yan, Chun-xia; Liu, Yan-ling; Deng, Ya-jun; Fulton, David J R; Chen, Teng

2009-10-01

The purpose of this study was to investigate mitochondrial DNA (mtDNA) hypervariable segment-I (HVS-I) C-stretch variations and explore the significance of these variations in forensic and population genetics studies. The C-stretch sequence variation was studied in 919 unrelated individuals from 8 Chinese ethnic groups using both direct and clone sequencing approaches. Thirty eight C-stretch haplotypes were identified, and some novel and population specific haplotypes were also detected. The C-stretch genetic diversity (GD) values were relatively high, and probability (P) values were low. Additionally, C-stretch length heteroplasmy was observed in approximately 9% of individuals studied. There was a significant correlation (r=-0.961, P<0.01) between the expansion of the cytosine sequence length in the C-stretch of HVS-I and a reduction in the number of upstream adenines. These results indicate that the C-stretch could be a useful genetic maker in forensic identification of Chinese populations. The results from the Fst and dA genetic distance matrix, neighbor-joining tree, and principal component map also suggest that C-stretch could be used as a reliable genetic marker in population genetics.

Effect of Static and Dynamic Stretching on the Diurnal Variations of Jump Performance in Soccer Players

PubMed Central

Chtourou, Hamdi; Aloui, Asma; Hammouda, Omar; Chaouachi, Anis; Chamari, Karim; Souissi, Nizar

2013-01-01

Purpose The present study addressed the lack of data on the effect of different types of stretching on diurnal variations in vertical jump height - i.e., squat-jump (SJ) and countermovement-jump (CMJ). We hypothesized that dynamic stretching could affect the diurnal variations of jump height by producing a greater increase in short-term maximal performance in the morning than the evening through increasing core temperature at this time-of-day. Methods Twenty male soccer players (age, 18.6±1.3 yrs; height, 174.6±3.8 cm; body-mass, 71.1±8.6 kg; mean ± SD) completed the SJ and CMJ tests either after static stretching, dynamic stretching or no-stretching protocols at two times of day, 07:00 h and 17:00 h, with a minimum of 48 hours between testing sessions. One minute after warming-up for 5 minutes by light jogging and performing one of the three stretching protocols (i.e., static stretching, dynamic stretching or no-stretching) for 8 minutes, each subject completed the SJ and CMJ tests. Jumping heights were recorded and analyzed using a two-way analysis of variance with repeated measures (3 [stretching]×2 [time-of-day]). Results The SJ and CMJ heights were significantly higher at 17:00 than 07:00 h (p<0.01) after the no-stretching protocol. These daily variations disappeared (i.e., the diurnal gain decreased from 4.2±2.81% (p<0.01) to 1.81±4.39% (not-significant) for SJ and from 3.99±3.43% (p<0.01) to 1.51±3.83% (not-significant) for CMJ) after dynamic stretching due to greater increases in SJ and CMJ heights in the morning than the evening (8.4±6.36% vs. 4.4±2.64%, p<0.05 for SJ and 10.61±5.49% vs. 6.03±3.14%, p<0.05 for CMJ). However, no significant effect of static stretching on the diurnal variations of SJ and CMJ heights was observed. Conclusion Dynamic stretching affects the typical diurnal variations of SJ and CMJ and helps to counteract the lower morning values in vertical jump height. PMID:23940589

Shortwave radiation parameterization scheme for subgrid topography

NASA Astrophysics Data System (ADS)

Helbig, N.; LöWe, H.

2012-02-01

Topography is well known to alter the shortwave radiation balance at the surface. A detailed radiation balance is therefore required in mountainous terrain. In order to maintain the computational performance of large-scale models while at the same time increasing grid resolutions, subgrid parameterizations are gaining more importance. A complete radiation parameterization scheme for subgrid topography accounting for shading, limited sky view, and terrain reflections is presented. Each radiative flux is parameterized individually as a function of sky view factor, slope and sun elevation angle, and albedo. We validated the parameterization with domain-averaged values computed from a distributed radiation model which includes a detailed shortwave radiation balance. Furthermore, we quantify the individual topographic impacts on the shortwave radiation balance. Rather than using a limited set of real topographies we used a large ensemble of simulated topographies with a wide range of typical terrain characteristics to study all topographic influences on the radiation balance. To this end slopes and partial derivatives of seven real topographies from Switzerland and the United States were analyzed and Gaussian statistics were found to best approximate real topographies. Parameterized direct beam radiation presented previously compared well with modeled values over the entire range of slope angles. The approximation of multiple, anisotropic terrain reflections with single, isotropic terrain reflections was confirmed as long as domain-averaged values are considered. The validation of all parameterized radiative fluxes showed that it is indeed not necessary to compute subgrid fluxes in order to account for all topographic influences in large grid sizes.

Analysis of sensitivity to different parameterization schemes for a subtropical cyclone

NASA Astrophysics Data System (ADS)

Quitián-Hernández, L.; Fernández-González, S.; González-Alemán, J. J.; Valero, F.; Martín, M. L.

2018-05-01

A sensitivity analysis to diverse WRF model physical parameterization schemes is carried out during the lifecycle of a Subtropical cyclone (STC). STCs are low-pressure systems that share tropical and extratropical characteristics, with hybrid thermal structures. In October 2014, a STC made landfall in the Canary Islands, causing widespread damage from strong winds and precipitation there. The system began to develop on October 18 and its effects lasted until October 21. Accurate simulation of this type of cyclone continues to be a major challenge because of its rapid intensification and unique characteristics. In the present study, several numerical simulations were performed using the WRF model to do a sensitivity analysis of its various parameterization schemes for the development and intensification of the STC. The combination of parameterization schemes that best simulated this type of phenomenon was thereby determined. In particular, the parameterization combinations that included the Tiedtke cumulus schemes had the most positive effects on model results. Moreover, concerning STC track validation, optimal results were attained when the STC was fully formed and all convective processes stabilized. Furthermore, to obtain the parameterization schemes that optimally categorize STC structure, a verification using Cyclone Phase Space is assessed. Consequently, the combination of parameterizations including the Tiedtke cumulus schemes were again the best in categorizing the cyclone's subtropical structure. For strength validation, related atmospheric variables such as wind speed and precipitable water were analyzed. Finally, the effects of using a deterministic or probabilistic approach in simulating intense convective phenomena were evaluated.

Acute effects of static stretching on passive stiffness of the hamstring muscles calculated using different mathematical models.

PubMed

Nordez, Antoine; Cornu, Christophe; McNair, Peter

2006-08-01

The aim of this study was to assess the effects of static stretching on hamstring passive stiffness calculated using different data reduction methods. Subjects performed a maximal range of motion test, five cyclic stretching repetitions and a static stretching intervention that involved five 30-s static stretches. A computerised dynamometer allowed the measurement of torque and range of motion during passive knee extension. Stiffness was then calculated as the slope of the torque-angle relationship fitted using a second-order polynomial, a fourth-order polynomial, and an exponential model. The second-order polynomial and exponential models allowed the calculation of stiffness indices normalized to knee angle and passive torque, respectively. Prior to static stretching, stiffness levels were significantly different across the models. After stretching, while knee maximal joint range of motion increased, stiffness was shown to decrease. Stiffness decreased more at the extended knee joint angle, and the magnitude of change depended upon the model used. After stretching, the stiffness indices also varied according to the model used to fit data. Thus, the stiffness index normalized to knee angle was found to decrease whereas the stiffness index normalized to passive torque increased after static stretching. Stretching has significant effects on stiffness, but the findings highlight the need to carefully assess the effect of different models when analyzing such data.

Regulation of extracellular matrix elements and sarcomerogenesis in response to different periods of passive stretching in the soleus muscle of rats.

PubMed

Peviani, Sabrina M; Guzzoni, Vinicius; Pinheiro-Dardis, Clara M; Silva, Yara P da; Fioravante, Alisson C R; Sagawa, Adriana H; Delfino, Gabriel B; Durigan, João L Q; Salvini, Tania F

2018-06-13

Stretching is a common method used to prevent muscle shortening and improve limited mobility. However, the effect of different time periods on stretching-induced adaptation of the extracellular matrix and its regulatory elements have yet to be investigated. We aimed to evaluate the expression of fibrillar collagens, sarcomerogenesis, metalloproteinase (MMP) activity and gene expression of the extracellular matrix (ECM) regulators in the soleus (SOL) muscle of rats submitted to different stretching periods. The soleus muscles were submitted to 10 sets of passive stretching over 10 (St 10d) or 15 days (St 15d) (1 min per set, with 30 seconds' rest between sets). Sarcomerogenesis, muscle cross-sectional area (CSA), and MMP activity and mRNA levels in collagen (type I, III and IV), connective tissue growth factor (CTGF), growth factor-beta (TGF-β), and lysyl oxidase (LOX) were analyzed. Passive stretching over both time periods mitigated COL-I deposition in the SOL muscle of rats. Paradoxically, 10 days of passive stretching induced COL-I and COL-III synthesis, with concomitant upregulation of TGF-β1 and CTGF at a transcriptional level. These responses may be associated with lower LOX mRNA levels in SOL muscles submitted to 10 passive stretching sessions. Moreover, sarcomerogenesis was observed after 15 days of stretching, suggesting that stretching-induced muscle adaptations are time-dependent responses.

A Comparison of the Immediate Effects of Eccentric Training vs Static Stretch on Hamstring Flexibility in High School and College Athletes.

PubMed

Nelson, Russell T

2006-05-01

A pre-event static stretching program is often used to prepare an athlete for competition. Recent studies have suggested that static stretching may not be an effective method for stretching the muscle prior to competition. The intent of this study was to compare the immediate effect of static stretching, eccentric training, and no stretching/training on hamstring flexibility in high school and college athletes. Seventy-five athletes, with a mean age of 17.22 (+/- 1.30) were randomly assigned to one of three groups - thirty- second static stretch one time, an eccentric training protocol through a full range of motion, and a control group. All athletes had limited hamstring flexibility, defined as a 20° loss of knee extension measured with the femur held at 90° of hip flexion. A significant difference was indicated by follow up analysis between the control group (gain = -1.08°) and both the static stretch (gain = 5.05°) and the eccentric training group (gain = 9.48°). In addition, the gains in the eccentric training group were significantly greater than the static stretch group. The findings of this study reveal that one session of eccentrically training through a full range of motion improved hamstring flexibility better than the gains made by a static stretch group or a control group.

A Comparison of the Immediate Effects of Eccentric Training vs Static Stretch on Hamstring Flexibility in High School and College Athletes

PubMed Central

2006-01-01

Background A pre-event static stretching program is often used to prepare an athlete for competition. Recent studies have suggested that static stretching may not be an effective method for stretching the muscle prior to competition. Objective The intent of this study was to compare the immediate effect of static stretching, eccentric training, and no stretching/training on hamstring flexibility in high school and college athletes. Methods Seventy-five athletes, with a mean age of 17.22 (+/- 1.30) were randomly assigned to one of three groups - thirty- second static stretch one time, an eccentric training protocol through a full range of motion, and a control group. All athletes had limited hamstring flexibility, defined as a 20° loss of knee extension measured with the femur held at 90° of hip flexion. Results A significant difference was indicated by follow up analysis between the control group (gain = -1.08°) and both the static stretch (gain = 5.05°) and the eccentric training group (gain = 9.48°). In addition, the gains in the eccentric training group were significantly greater than the static stretch group. Discussion and Conclusion The findings of this study reveal that one session of eccentrically training through a full range of motion improved hamstring flexibility better than the gains made by a static stretch group or a control group. PMID:21522215

Ceiling Fires Studied to Simulate Low-Gravity Fires

NASA Technical Reports Server (NTRS)

Olson, Sandra L.

2001-01-01

A unique new way to study low-gravity flames in normal gravity has been developed. To study flame structure and extinction characteristics in low-stretch environments, a normal gravity low-stretch diffusion flame was generated using a cylindrical PMMA sample of varying large radii, as shown in the photograph. These experiments have demonstrated that low-gravity flame characteristics can be generated in normal gravity through the proper use of scaling. On the basis of this work, it is feasible to apply this concept toward the development of an Earth-bound method of evaluating material flammability in various gravitational environments from normal gravity to microgravity, including the effects of partial gravity low-stretch rates such as those found on the Moon (1/6g) or Mars (1/3g). During these experiments, the surface regression rates for PMMA were measured for the first time over the full range of flammability in air, from blowoff at high stretch, to quenching at low stretch, as plotted in the graph. The solid line drawn through the central portion of the data (3

Quantifying the magnitude of torque physiotherapists apply when stretching the hamstring muscles of people with spinal cord injury.

PubMed

Harvey, Lisa A; McQuade, Lea; Hawthorne, Scott; Byak, Adrian

2003-07-01

To quantify the magnitude of stretch that physiotherapists apply to the hamstring muscles of people with spinal cord injury (SCI). Repeated-measures design. SCI unit in Australia. Fifteen individuals with motor complete paraplegia or tetraplegia. Twelve physiotherapists manually administered a stretch to the hamstring muscles of each subject. The stretch was applied by flexing the hip with the knee extended. Applied hip flexor torque. Therapists applied median hip flexor torques of between 30 and 68Nm, although some torques were as large as 121Nm. The stretch applied by different therapists to any 1 subject varied as much as 40-fold. There is a large range of stretch torques provided by physiotherapists to patients with SCI. Some therapists provide stretch torques well in excess of those tolerated by individuals with intact sensation.

UNCOVERING THE INTRINSIC VARIABILITY OF GAMMA-RAY BURSTS

NASA Astrophysics Data System (ADS)

Golkhou, V. Zach; Butler, Nathaniel R

2014-08-01

We develop a robust technique to determine the minimum variability timescale for gamma-ray burst (GRB) light curves, utilizing Haar wavelets. Our approach averages over the data for a given GRB, providing an aggregate measure of signal variation while also retaining sensitivity to narrow pulses within complicated time series. In contrast to previous studies using wavelets, which simply define the minimum timescale in reference to the measurement noise floor, our approach identifies the signature of temporally smooth features in the wavelet scaleogram and then additionally identifies a break in the scaleogram on longer timescales as a signature of a true, temporally unsmooth light curve feature or features. We apply our technique to the large sample of Swift GRB gamma-ray light curves and for the first time—due to the presence of a large number of GRBs with measured redshift—determine the distribution of minimum variability timescales in the source frame. We find a median minimum timescale for long-duration GRBs in the source frame of Δtmin = 0.5 s, with the shortest timescale found being on the order of 10 ms. This short timescale suggests a compact central engine (3000 km). We discuss further implications for the GRB fireball model and present a tantalizing correlation between the minimum timescale and redshift, which may in part be due to cosmological time dilation.

The Effectiveness of PNF Versus Static Stretching on Increasing Hip-Flexion Range of Motion.

PubMed

Lempke, Landon; Wilkinson, Rebecca; Murray, Caitlin; Stanek, Justin

2018-05-22

Clinical Scenario: Stretching is applied for the purposes of injury prevention, increasing joint range of motion (ROM), and increasing muscle extensibility. Many researchers have investigated various methods and techniques to determine the most effective way to increase joint ROM and muscle extensibility. Despite the numerous studies conducted, controversy still remains within clinical practice and the literature regarding the best methods and techniques for stretching. Focused Clinical Question: Is proprioceptive neuromuscular facilitation (PNF) stretching more effective than static stretching for increasing hamstring muscle extensibility through increased hip ROM or increased knee extension angle (KEA) in a physically active population? Summary of Key Findings: Five studies met the inclusion criteria and were included. All 5 studies were randomized control trials examining mobility of the hamstring group. The studies measured hamstring ROM in a variety of ways. Three studies measured active KEA, 1 study measured passive KEA, and 1 study measured hip ROM via the single-leg raise test. Of the 5 studies, 1 study found greater improvements using PNF over static stretching for increasing hip flexion, and the remaining 4 studies found no significant difference between PNF stretching and static stretching in increasing muscle extensibility, active KEA, or hip ROM. Clinical Bottom Line: PNF stretching was not demonstrated to be more effective at increasing hamstring extensibility compared to static stretching. The literature reviewed suggests both are effective methods for increasing hip-flexion ROM. Strength of Recommendation: Using level 2 evidence and higher, the results show both static and PNF stretching effectively increase ROM; however, one does not appear to be more effective than the other.

Low Stretch PMMA Burning in Microgravity: Status of the Ground-Based Program and New ISS Glovebox Experiment SALSA

NASA Technical Reports Server (NTRS)

Olson, S. L.; T'ien, J. S.; Armstrong, J. B.

2001-01-01

The objective of this ground-based program is to study low stretch diffusion flames burning PMMA as the solid fuel to determine the relationship between buoyant low stretch burning in normal gravity and forced flow low stretch burning in microgravity. The low stretch is generated in normal gravity by using the buoyant convection induced by burning the bottom of a large radius of curvature sample. Low stretch is also generated using the Combustion Tunnel drop tower rig (2.2 and 5.2 second facilities), which provides a forced convective low velocity flow past smaller radius of curvature samples. Lastly, an ISS glovebox investigation is being developed to study low stretch burning of PMMA spheres to obtain long duration testing needed to accurately assess the flammability and burning characteristics of the material in microgravity. A comparison of microgravity experiment results with normal gravity test results allows us to establish a direct link between a material's burning characteristics in normal gravity (easily measured) with its burning characteristics in extraterrestrial environments, including microgravity forced convective environments. Theoretical predictions and recent experimental results indicate that it should be possible to understand a material's burning characteristics in the low stretch environment of spacecraft (non-buoyant air movement induced by fans and crew disturbances) by understanding its burning characteristics in an equivalent Earth-based low stretch environment (induced by normal gravity buoyancy). Similarly, Earth-based stretch environments can be made equivalent to those in Lunar- and Martian-surface stretch environments (which would induce partial-gravity buoyancy).

49 CFR 180.413 - Repair, modification, stretching, rebarrelling, or mounting of specification cargo tanks.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 3 2014-10-01 2014-10-01 false Repair, modification, stretching, rebarrelling, or... Tanks § 180.413 Repair, modification, stretching, rebarrelling, or mounting of specification cargo tanks. (a) General. Any repair, modification, stretching, rebarrelling, or mounting of a cargo tank must be...

49 CFR 180.413 - Repair, modification, stretching, rebarrelling, or mounting of specification cargo tanks.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 3 2013-10-01 2013-10-01 false Repair, modification, stretching, rebarrelling, or... Tanks § 180.413 Repair, modification, stretching, rebarrelling, or mounting of specification cargo tanks. (a) General. Any repair, modification, stretching, rebarrelling, or mounting of a cargo tank must be...

49 CFR 180.413 - Repair, modification, stretching, rebarrelling, or mounting of specification cargo tanks.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 3 2012-10-01 2012-10-01 false Repair, modification, stretching, rebarrelling, or... Tanks § 180.413 Repair, modification, stretching, rebarrelling, or mounting of specification cargo tanks. (a) General. Any repair, modification, stretching, rebarrelling, or mounting of a cargo tank must be...

49 CFR 180.413 - Repair, modification, stretching, rebarrelling, or mounting of specification cargo tanks.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 3 2011-10-01 2011-10-01 false Repair, modification, stretching, rebarrelling, or... Tanks § 180.413 Repair, modification, stretching, rebarrelling, or mounting of specification cargo tanks. (a) General. Any repair, modification, stretching, rebarrelling, or mounting of a cargo tank must be...

Sensitivity of Glacier Mass Balance Estimates to the Selection of WRF Cloud Microphysics Parameterization in the Indus River Watershed

NASA Astrophysics Data System (ADS)

Johnson, E. S.; Rupper, S.; Steenburgh, W. J.; Strong, C.; Kochanski, A.

2017-12-01

Climate model outputs are often used as inputs to glacier energy and mass balance models, which are essential glaciological tools for testing glacier sensitivity, providing mass balance estimates in regions with little glaciological data, and providing a means to model future changes. Climate model outputs, however, are sensitive to the choice of physical parameterizations, such as those for cloud microphysics, land-surface schemes, surface layer options, etc. Furthermore, glacier mass balance (MB) estimates that use these climate model outputs as inputs are likely sensitive to the specific parameterization schemes, but this sensitivity has not been carefully assessed. Here we evaluate the sensitivity of glacier MB estimates across the Indus Basin to the selection of cloud microphysics parameterizations in the Weather Research and Forecasting Model (WRF). Cloud microphysics parameterizations differ in how they specify the size distributions of hydrometeors, the rate of graupel and snow production, their fall speed assumptions, the rates at which they convert from one hydrometeor type to the other, etc. While glacier MB estimates are likely sensitive to other parameterizations in WRF, our preliminary results suggest that glacier MB is highly sensitive to the timing, frequency, and amount of snowfall, which is influenced by the cloud microphysics parameterization. To this end, the Indus Basin is an ideal study site, as it has both westerly (winter) and monsoonal (summer) precipitation influences, is a data-sparse region (so models are critical), and still has lingering questions as to glacier importance for local and regional resources. WRF is run at a 4 km grid scale using two commonly used parameterizations: the Thompson scheme and the Goddard scheme. On average, these parameterizations result in minimal differences in annual precipitation. However, localized regions exhibit differences in precipitation of up to 3 m w.e. a-1. The different schemes also impact the radiative budgets over the glacierized areas. Our results show that glacier MB estimates can differ by up to 45% depending on the chosen cloud microphysics scheme. These findings highlight the need to better account for uncertainties in meteorological inputs into glacier energy and mass balance models.

Towards a unified Global Weather-Climate Prediction System

NASA Astrophysics Data System (ADS)

Lin, S. J.

2016-12-01

The Geophysical Fluid Dynamics Laboratory has been developing a unified regional-global modeling system with variable resolution capabilities that can be used for severe weather predictions and kilometer scale regional climate simulations within a unified global modeling system. The foundation of this flexible modeling system is the nonhydrostatic Finite-Volume Dynamical Core on the Cubed-Sphere (FV3). A unique aspect of FV3 is that it is "vertically Lagrangian" (Lin 2004), essentially reducing the equation sets to two dimensions, and is the single most important reason why FV3 outperforms other non-hydrostatic cores. Owning to its accuracy, adaptability, and computational efficiency, the FV3 has been selected as the "engine" for NOAA's Next Generation Global Prediction System (NGGPS). We have built into the modeling system a stretched grid, a two-way regional-global nested grid, and an optimal combination of the stretched and two-way nests capability, making kilometer-scale regional simulations within a global modeling system feasible. Our main scientific goal is to enable simulations of high impact weather phenomena (such as tornadoes, thunderstorms, category-5 hurricanes) within an IPCC-class climate modeling system previously regarded as impossible. In this presentation I will demonstrate that, with the FV3, it is computationally feasible to simulate not only super-cell thunderstorms, but also the subsequent genesis of tornado-like vortices using a global model that was originally designed for climate simulations. The development and tuning strategy between traditional weather and climate models are fundamentally different due to different metrics. We were able to adapt and use traditional "climate" metrics or standards, such as angular momentum conservation, energy conservation, and flux balance at top of the atmosphere, and gain insight into problems of traditional weather prediction model for medium-range weather prediction, and vice versa. Therefore, the unification in weather and climate models can happen not just at the algorithm or parameterization level, but also in the metric and tuning strategy used for both applications, and ultimately, with benefits to both weather and climate applications.

Stretch Garment Dermatitis

PubMed Central

Mihan, Richard; Ayres, Samuel

1968-01-01

A disease of the skin, not hitherto described, is caused by pressure or tension on the skin from the wearing of tight-fitting stretch garments such as “stretch bras,” “stretch girdles” and “stretch socks.” The condition is not due to chemical sensitization of fabrics, dyes or other additives but is of mechanical origin. The eruption may assume various clinical forms and may be characterized by a nondescript erythematous and eczematous appearance or may consist of an exaggeration, in the areas covered by the stretch garment, of already existing dermatosis such as lichen planus, psoriasis, acne vulgaris, discoid lupus erythematosus or atopic dermatitis. ImagesFigure 1.Figure 2.Figure 3.Figure 4.Figure 5. PMID:5639939

Testing a common ice-ocean parameterization with laboratory experiments

NASA Astrophysics Data System (ADS)

McConnochie, C. D.; Kerr, R. C.

2017-07-01

Numerical models of ice-ocean interactions typically rely upon a parameterization for the transport of heat and salt to the ice face that has not been satisfactorily validated by observational or experimental data. We compare laboratory experiments of ice-saltwater interactions to a common numerical parameterization and find a significant disagreement in the dependence of the melt rate on the fluid velocity. We suggest a resolution to this disagreement based on a theoretical analysis of the boundary layer next to a vertical heated plate, which results in a threshold fluid velocity of approximately 4 cm/s at driving temperatures between 0.5 and 4°C, above which the form of the parameterization should be valid.

Parameterization of light absorption by components of seawater in optically complex coastal waters of the Crimea Peninsula (Black Sea).

PubMed

Dmitriev, Egor V; Khomenko, Georges; Chami, Malik; Sokolov, Anton A; Churilova, Tatyana Y; Korotaev, Gennady K

2009-03-01

The absorption of sunlight by oceanic constituents significantly contributes to the spectral distribution of the water-leaving radiance. Here it is shown that current parameterizations of absorption coefficients do not apply to the optically complex waters of the Crimea Peninsula. Based on in situ measurements, parameterizations of phytoplankton, nonalgal, and total particulate absorption coefficients are proposed. Their performance is evaluated using a log-log regression combined with a low-pass filter and the nonlinear least-square method. Statistical significance of the estimated parameters is verified using the bootstrap method. The parameterizations are relevant for chlorophyll a concentrations ranging from 0.45 up to 2 mg/m(3).

A second-order Budkyo-type parameterization of landsurface hydrology

NASA Technical Reports Server (NTRS)

Andreou, S. A.; Eagleson, P. S.

1982-01-01

A simple, second order parameterization of the water fluxes at a land surface for use as the appropriate boundary condition in general circulation models of the global atmosphere was developed. The derived parameterization incorporates the high nonlinearities in the relationship between the near surface soil moisture and the evaporation, runoff and percolation fluxes. Based on the one dimensional statistical dynamic derivation of the annual water balance, it makes the transition to short term prediction of the moisture fluxes, through a Taylor expansion around the average annual soil moisture. A comparison of the suggested parameterization is made with other existing techniques and available measurements. A thermodynamic coupling is applied in order to obtain estimations of the surface ground temperature.

Evidence of strategic periodicities in collective conflict dynamics.

PubMed

Dedeo, Simon; Krakauer, David; Flack, Jessica

2011-09-07

We analyse the timescales of conflict decision-making in a primate society. We present evidence for multiple, periodic timescales associated with social decision-making and behavioural patterns. We demonstrate the existence of periodicities that are not directly coupled to environmental cycles or known ultraridian mechanisms. Among specific biological and socially defined demographic classes, periodicities span timescales between hours and days. Our results indicate that these periodicities are not driven by exogenous or internal regularities but are instead driven by strategic responses to social interaction patterns. Analyses also reveal that a class of individuals, playing a critical functional role, policing, have a signature timescale of the order of 1 h. We propose a classification of behavioural timescales analogous to those of the nervous system, with high frequency, or α-scale, behaviour occurring on hour-long scales, through to multi-hour, or β-scale, behaviour, and, finally γ periodicities observed on a timescale of days.

Lagrangian Timescales of Southern Ocean Upwelling in a Hierarchy of Model Resolutions

NASA Astrophysics Data System (ADS)

Drake, Henri F.; Morrison, Adele K.; Griffies, Stephen M.; Sarmiento, Jorge L.; Weijer, Wilbert; Gray, Alison R.

2018-01-01

In this paper we study upwelling pathways and timescales of Circumpolar Deep Water (CDW) in a hierarchy of models using a Lagrangian particle tracking method. Lagrangian timescales of CDW upwelling decrease from 87 years to 31 years to 17 years as the ocean resolution is refined from 1° to 0.25° to 0.1°. We attribute some of the differences in timescale to the strength of the eddy fields, as demonstrated by temporally degrading high-resolution model velocity fields. Consistent with the timescale dependence, we find that an average Lagrangian particle completes 3.2 circumpolar loops in the 1° model in comparison to 0.9 loops in the 0.1° model. These differences suggest that advective timescales and thus interbasin merging of upwelling CDW may be overestimated by coarse-resolution models, potentially affecting the skill of centennial scale climate change projections.

Effect of Lower Extremity Stretching Exercises on Balance in Geriatric Population.

PubMed

Reddy, Ravi Shankar; Alahmari, Khalid A

2016-07-01

The purpose of this study was to find "Effect of lower extremity stretching exercises on balance in the geriatric population. 60 subjects (30 male and 30 female) participated in the study. The subjects underwent 10 weeks of lower limb stretching exercise program. Pre and post 10 weeks stretching exercise program, the subjects were assessed for balance, using single limb stance time in seconds and berg balance score. These outcome measures were analyzed. Pre and post lower extremity stretching on balance was analyzed using paired t test. Of 60 subjects 50 subjects completed the stretching exercise program. Paired sample t test analysis showed a significant improvement in single limb stance time (eyes open and eyes closed) (p<0.001) and berg balance score (p<0.001). Lower extremity stretching exercises enhances balance in the geriatric population and thereby reduction in the number of falls.

Can Stretching Prior to Exercise and Sports Improve Performance and Prevent Injury?

ERIC Educational Resources Information Center

Bracko, Michael R.

2002-01-01

Examines data from research on stretching as it relates to enhanced performance and injury prevention so that fitness, exercise, and sports performance professionals can make informed decisions about stretching programs for clients. The paper notes that stretching is a misunderstood component of fitness and sports training. Few studies show…

A Single 30-s Stretch Is Sufficient to Inhibit Maximal Voluntary Strength

ERIC Educational Resources Information Center

Winchester, Jason B.; Nelson, Arnold G.; Kokkonen, Joke

2009-01-01

While it has been well established that an acute stretching program can inhibit maximal muscle performance, the amount of stretching needed to produce the deleterious response is unknown. Therefore this study examined the dose-response relationship between acute stretching and strength inhibition. Eighteen college students performed a one…

Pulsatile equibiaxial stretch inhibits thrombin-induced RhoA and NF-{kappa}B activation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haga, Jason H.; Kaunas, Roland; Radeff-Huang, Julie

2008-07-18

This study investigated interactions between the effects of mechanical stretch and thrombin on RhoA activation in rat aortic smooth muscle cells (RASMC). Equibiaxial, pulsatile stretch, or thrombin produced a significant increase in RhoA activation. Surprisingly, in combination, 30 min of stretch inhibited the ability of thrombin to activate RhoA. NO donors and 8-bromo-cGMP significantly inhibited thrombin-induced RhoA activation. Interestingly, the nitric oxide synthase (NOS) inhibitor L-NAME increased basal RhoA activity, suggesting that NOS activity exerts a tonic inhibition on RhoA. Stretching RASMC increases nitrite production, consistent with the idea that NO contributes to the inhibitory effects of stretch. Thrombin stimulatesmore » MAP kinase and NF-{kappa}B pathways through Rho and these responses were blocked by 8-bromo-cGMP or stretch and restored by L-NAME. These data suggest that stretch, acting through NO and cGMP, can prevent the ability of thrombin to stimulate Rho signaling pathways that contribute to pathophysiological proliferative and inflammatory responses.« less

Electron Impact Ionization: A New Parameterization for 100 eV to 1 MeV Electrons

NASA Technical Reports Server (NTRS)

Fang, Xiaohua; Randall, Cora E.; Lummerzheim, Dirk; Solomon, Stanley C.; Mills, Michael J.; Marsh, Daniel; Jackman, Charles H.; Wang, Wenbin; Lu, Gang

2008-01-01

Low, medium and high energy electrons can penetrate to the thermosphere (90-400 km; 55-240 miles) and mesosphere (50-90 km; 30-55 miles). These precipitating electrons ionize that region of the atmosphere, creating positively charged atoms and molecules and knocking off other negatively charged electrons. The precipitating electrons also create nitrogen-containing compounds along with other constituents. Since the electron precipitation amounts change within minutes, it is necessary to have a rapid method of computing the ionization and production of nitrogen-containing compounds for inclusion in computationally-demanding global models. A new methodology has been developed, which has parameterized a more detailed model computation of the ionizing impact of precipitating electrons over the very large range of 100 eV up to 1,000,000 eV. This new parameterization method is more accurate than a previous parameterization scheme, when compared with the more detailed model computation. Global models at the National Center for Atmospheric Research will use this new parameterization method in the near future.

Parameterization of Shortwave Cloud Optical Properties for a Mixture of Ice Particle Habits for use in Atmospheric Models

NASA Technical Reports Server (NTRS)

Chou, Ming-Dah; Lee, Kyu-Tae; Yang, Ping; Lau, William K. M. (Technical Monitor)

2002-01-01

Based on the single-scattering optical properties pre-computed with an improved geometric optics method, the bulk absorption coefficient, single-scattering albedo, and asymmetry factor of ice particles have been parameterized as a function of the effective particle size of a mixture of ice habits, the ice water amount, and spectral band. The parameterization has been applied to computing fluxes for sample clouds with various particle size distributions and assumed mixtures of particle habits. It is found that flux calculations are not overly sensitive to the assumed particle habits if the definition of the effective particle size is consistent with the particle habits that the parameterization is based. Otherwise, the error in the flux calculations could reach a magnitude unacceptable for climate studies. Different from many previous studies, the parameterization requires only an effective particle size representing all ice habits in a cloud layer, but not the effective size of individual ice habits.

Anisotropic shear dispersion parameterization for ocean eddy transport

NASA Astrophysics Data System (ADS)

Reckinger, Scott; Fox-Kemper, Baylor

2015-11-01

The effects of mesoscale eddies are universally treated isotropically in global ocean general circulation models. However, observations and simulations demonstrate that the mesoscale processes that the parameterization is intended to represent, such as shear dispersion, are typified by strong anisotropy. We extend the Gent-McWilliams/Redi mesoscale eddy parameterization to include anisotropy and test the effects of varying levels of anisotropy in 1-degree Community Earth System Model (CESM) simulations. Anisotropy has many effects on the simulated climate, including a reduction of temperature and salinity biases, a deepening of the southern ocean mixed-layer depth, impacts on the meridional overturning circulation and ocean energy and tracer uptake, and improved ventilation of biogeochemical tracers, particularly in oxygen minimum zones. A process-based parameterization to approximate the effects of unresolved shear dispersion is also used to set the strength and direction of anisotropy. The shear dispersion parameterization is similar to drifter observations in spatial distribution of diffusivity and high-resolution model diagnosis in the distribution of eddy flux orientation.

A unified spectral parameterization for wave breaking: From the deep ocean to the surf zone

NASA Astrophysics Data System (ADS)

Filipot, J.-F.; Ardhuin, F.

2012-11-01

A new wave-breaking dissipation parameterization designed for phase-averaged spectral wave models is presented. It combines wave breaking basic physical quantities, namely, the breaking probability and the dissipation rate per unit area. The energy lost by waves is first explicitly calculated in physical space before being distributed over the relevant spectral components. The transition from deep to shallow water is made possible by using a dissipation rate per unit area of breaking waves that varies with the wave height, wavelength and water depth. This parameterization is implemented in the WAVEWATCH III modeling framework, which is applied to a wide range of conditions and scales, from the global ocean to the beach scale. Wave height, peak and mean periods, and spectral data are validated using in situ and remote sensing data. Model errors are comparable to those of other specialized deep or shallow water parameterizations. This work shows that it is possible to have a seamless parameterization from the deep ocean to the surf zone.

Intra-binary Shock Heating of Black Widow Companions

NASA Astrophysics Data System (ADS)

Romani, Roger W.; Sanchez, Nicolas

2016-09-01

The low-mass companions of evaporating binary pulsars (black widows and similar) are strongly heated on the side facing the pulsar. However, in high-quality photometric and spectroscopic data, the heating pattern does not match that expected for direct pulsar illumination. Here we explore a model where the pulsar power is intercepted by an intra-binary shock (IBS) before heating the low-mass companion. We develop a simple analytic model and implement it in the popular “ICARUS” light curve code. The model is parameterized by the wind momentum ratio β and the companion wind speed {f}v{v}{{orb}}, and assumes that the reprocessed pulsar wind emits prompt particles or radiation to heat the companion surface. We illustrate an interesting range of light curve asymmetries controlled by these parameters. The code also computes the IBS synchrotron emission pattern, and thus can model black widow X-ray light curves. As a test, we apply the results to the high-quality asymmetric optical light curves of PSR J2215+5135; the resulting fit gives a substantial improvement upon direct heating models and produces an X-ray light curve consistent with that seen. The IBS model parameters imply that at the present loss rate, the companion evaporation has a characteristic timescale of {τ }{{evap}}≈ 150 Myr. Still, the model is not fully satisfactory, indicating that there are additional unmodeled physical effects.

Enhanced vadose zone nitrogen removal by poplar during dormancy.

PubMed

Ausland, Hayden; Ward, Adam; Licht, Louis; Just, Craig

2015-01-01

A pilot-scale, engineered poplar tree vadose zone system was utilized to determine effluent nitrate (NO3(-)) and ammonium concentrations resulting from intermittent dosing of a synthetic wastewater onto sandy soils at 4.5°C. The synthetic wastewater replicated that of an industrial food processor that irrigates onto sandy soils even during dormancy which can leave groundwater vulnerable to NO3(-) contamination. Data from a 21-day experiment was used to assess various Hydrus model parameterizations that simulated the impact of dormant roots. Bromide tracer data indicated that roots impacted the hydraulic properties of the packed sand by increasing effective dispersion, water content and residence time. The simulated effluent NO3(-) concentration on day 21 was 1.2 mg-N L(-1) in the rooted treatments compared to a measured value of 1.0 ± 0.72 mg-N L(-1). For the non-rooted treatment, the simulated NO3(-) concentration was 4.7 mg-N L(-1) compared to 5.1 ± 3.5 mg-N L(-1) measured on day 21. The model predicted a substantial "root benefit" toward protecting groundwater through increased denitrification in rooted treatments during a 21-day simulation with 8% of dosed nitrogen converted to N2 compared to 3.3% converted in the non-rooted test cells. Simulations at the 90-day timescale provided similar results, indicating increased denitrification in rooted treatments.

Constraining Centennial-Scale Ecosystem-Climate Interactions with a Pre-colonial Forest Reconstruction across the Upper Midwest and Northeastern United States

NASA Astrophysics Data System (ADS)

Matthes, J. H.; Dietze, M.; Fox, A. M.; Goring, S. J.; McLachlan, J. S.; Moore, D. J.; Poulter, B.; Quaife, T. L.; Schaefer, K. M.; Steinkamp, J.; Williams, J. W.

2014-12-01

Interactions between ecological systems and the atmosphere are the result of dynamic processes with system memories that persist from seconds to centuries. Adequately capturing long-term biosphere-atmosphere exchange within earth system models (ESMs) requires an accurate representation of changes in plant functional types (PFTs) through time and space, particularly at timescales associated with ecological succession. However, most model parameterization and development has occurred using datasets than span less than a decade. We tested the ability of ESMs to capture the ecological dynamics observed in paleoecological and historical data spanning the last millennium. Focusing on an area from the Upper Midwest to New England, we examined differences in the magnitude and spatial pattern of PFT distributions and ecotones between historic datasets and the CMIP5 inter-comparison project's large-scale ESMs. We then conducted a 1000-year model inter-comparison using six state-of-the-art biosphere models at sites that bridged regional temperature and precipitation gradients. The distribution of ecosystem characteristics in modeled climate space reveals widely disparate relationships between modeled climate and vegetation that led to large differences in long-term biosphere-atmosphere fluxes for this region. Model simulations revealed that both the interaction between climate and vegetation and the representation of ecosystem dynamics within models were important controls on biosphere-atmosphere exchange.

The CE way of thinking: "all is relative!".

PubMed

Schmitt-Kopplin, Philippe; Fekete, Agnes

2008-01-01

Over the last two decades, the development of capillary electrophoresis (CE) instruments has lead to systems with programmable samplers, separation columns, separation buffers, and detection devices comparable visually in many aspects to the setup of classical chromatography. Two characteristics make CE essentially different from chromatography and are the basis of the CE way of thinking: first is the injection type and the liquid flow within the capillary. When the injection is made hydrodynamically (such as in most of the applications found in the literature), the injected volumes are directly dependent on the type and size of the separation capillary. The second characteristic is that in CE, buffer velocity is not pressure-driven, as in liquid chromatography, but is electrokinetically governed by the quality of the capillary surface (separation buffer dependent surface charge) inducing an electroosmotic flow (EOF). The EOF undergoes small variations and is not necessarily identical from one separation or day to the other. The direct consequence is that the migration time of the analytes apparently nonreproducible, although the velocity of the ions is the same. The effective mobility (field strength normalized velocity) of the ions is a possible parameterization from acquired time-scale to effective mobility-scale electropherograms leading to a reproducible visualization and better quantification with a direct relation to structural characters of the analytes (i.e., charge and size; see Chapter 23).

Transient impact of prolonged versus repetitive stretch on hand motor control in chronic stroke.

PubMed

Triandafilou, Kristen M; Ochoa, Jose; Kang, Xuan; Fischer, Heidi C; Stoykov, Mary Ellen; Kamper, Derek G

2011-01-01

The purpose of this study was to investigate the influence of prolonged and repetitive passive range of motion (PROM) stretching of the fingers on hand function in stroke survivors. Fifteen chronic stroke survivors with moderate to severe hand impairment took part in the study. Participants underwent 3 experimental sessions consisting of 30 minutes of rest, prolonged, or repetitive stretching of the finger flexor muscles by a powered glove orthosis (X-Glove). Outcome measures, comprised of 3 selected tasks from the Graded Wolf Motor Function Test (GWMFT), grip strength, lateral pinch strength, and grip relaxation time, were recorded at the start and end of each session. Change in outcome score for each session was used for analysis. Data suggested a trend for improvement following stretching, especially for the repetitive PROM case. For one GWMFT task (lift washcloth), the effect of stretching condition on performance time approached a statistical significance (P = .015), with repetitive PROM stretching producing the greatest mean reduction. Similarly, repetitive stretching led to a 12% ± 16% increase in grip strength, although this change was not statistically different across groups (P = .356); and grip termination time was reduced, albeit non-significantly, by 66% ± 133%. Repetitive PROM stretching exhibited trends to be more effective than prolonged stretching for improving hand motor control. Although the results were highly variable and the effects are undoubtedly transient, an extended period of repetitive PROM stretching may prove advantageous prior to hand therapy sessions to maximize treatment.

Stretching-induced nanostructures on shape memory polyurethane films and their regulation to osteoblasts morphology.

PubMed

Xing, Juan; Ma, Yufei; Lin, Manping; Wang, Yuanliang; Pan, Haobo; Ruan, Changshun; Luo, Yanfeng

2016-10-01

Programming such as stretching, compression and bending is indispensible to endow polyurethanes with shape memory effects. Despite extensive investigations on the contributions of programming processes to the shape memory effects of polyurethane, less attention has been paid to the nanostructures of shape memory polyurethanes surface during the programming process. Here we found that stretching could induce the reassembly of hard domains and thereby change the nanostructures on the film surfaces with dependence on the stretching ratios (0%, 50%, 100%, and 200%). In as-cast polyurethane films, hard segments sequentially assembled into nano-scale hard domains, round or fibrillar islands, and fibrillar apophyses. Upon stretching, the islands packed along the stretching axis to form reoriented fibrillar apophyses along the stretching direction. Stretching only changed the chemical patterns on polyurethane films without significantly altering surface roughness, with the primary composition of fibrillar apophyses being hydrophilic hard domains. Further analysis of osteoblasts morphology revealed that the focal adhesion formation and osteoblasts orientation were in accordance with the chemical patterns of the underlying stretched films, which corroborates the vital roles of stretching-induced nanostructures in regulating osteoblasts morphology. These novel findings suggest that programming might hold great potential for patterning polyurethane surfaces so as to direct cellular behavior. In addition, this work lays groundwork for guiding the programming of shape memory polyurethanes to produce appropriate nanostructures for predetermined medical applications. Copyright © 2016 Elsevier B.V. All rights reserved.

Acute Effect of Different Combined Stretching Methods on Acceleration and Speed in Soccer Players.

PubMed

Amiri-Khorasani, Mohammadtaghi; Calleja-Gonzalez, Julio; Mogharabi-Manzari, Mansooreh

2016-04-01

The purpose of this study was to investigate the acute effect of different stretching methods, during a warm-up, on the acceleration and speed of soccer players. The acceleration performance of 20 collegiate soccer players (body height: 177.25 ± 5.31 cm; body mass: 65.10 ± 5.62 kg; age: 16.85 ± 0.87 years; BMI: 20.70 ± 5.54; experience: 8.46 ± 1.49 years) was evaluated after different warm-up procedures, using 10 and 20 m tests. Subjects performed five types of a warm-up: static, dynamic, combined static + dynamic, combined dynamic + static, and no-stretching. Subjects were divided into five groups. Each group performed five different warm-up protocols in five non-consecutive days. The warm-up protocol used for each group was randomly assigned. The protocols consisted of 4 min jogging, a 1 min stretching program (except for the no-stretching protocol), and 2 min rest periods, followed by the 10 and 20 m sprint test, on the same day. The current findings showed significant differences in the 10 and 20 m tests after dynamic stretching compared with static, combined, and no-stretching protocols. There were also significant differences between the combined stretching compared with static and no-stretching protocols. We concluded that soccer players performed better with respect to acceleration and speed, after dynamic and combined stretching, as they were able to produce more force for a faster execution.

Effects of special composite stretching on the swing of amateur golf players

PubMed Central

Lee, Joong-chul; Lee, Sung-wan; Yeo, Yun-ghi; Park, Gi Duck

2015-01-01

[Purpose] The study investigated stretching for safer a golf swing compared to present stretching methods for proper swings in order to examine the effects of stretching exercises on golf swings. [Subjects] The subjects were 20 amateur golf club members who were divided into two groups: an experimental group which performed stretching, and a control group which did not. The subjects had no bone deformity, muscle weakness, muscle soreness, or neurological problems. [Methods] A swing analyzer and a ROM measuring instrument were used as the measuring tools. The swing analyzer was a GS400-golf hit ball analyzer (Korea) and the ROM measuring instrument was a goniometer (Korea). [Results] The experimental group showed a statistically significant improvement in driving distance. After the special stretching training for golf, a statistically significant difference in hit-ball direction deviation after swings were found between the groups. The experimental group showed statistically significant decreases in hit ball direction deviation. After the special stretching training for golf, statistically significant differences in hit-ball speed were found between the groups. The experimental group showed significant increases in hit-ball speed. [Conclusion] To examine the effects of a special stretching program for golf on golf swing-related factors, 20 male amateur golf club members performed a 12-week stretching training program. After the golf stretching training, statistically significant differences were found between the groups in hit-ball driving distance, direction deviation, deflection distance, and speed. PMID:25995553

Effects of special composite stretching on the swing of amateur golf players.

PubMed

Lee, Joong-Chul; Lee, Sung-Wan; Yeo, Yun-Ghi; Park, Gi Duck

2015-04-01

[Purpose] The study investigated stretching for safer a golf swing compared to present stretching methods for proper swings in order to examine the effects of stretching exercises on golf swings. [Subjects] The subjects were 20 amateur golf club members who were divided into two groups: an experimental group which performed stretching, and a control group which did not. The subjects had no bone deformity, muscle weakness, muscle soreness, or neurological problems. [Methods] A swing analyzer and a ROM measuring instrument were used as the measuring tools. The swing analyzer was a GS400-golf hit ball analyzer (Korea) and the ROM measuring instrument was a goniometer (Korea). [Results] The experimental group showed a statistically significant improvement in driving distance. After the special stretching training for golf, a statistically significant difference in hit-ball direction deviation after swings were found between the groups. The experimental group showed statistically significant decreases in hit ball direction deviation. After the special stretching training for golf, statistically significant differences in hit-ball speed were found between the groups. The experimental group showed significant increases in hit-ball speed. [Conclusion] To examine the effects of a special stretching program for golf on golf swing-related factors, 20 male amateur golf club members performed a 12-week stretching training program. After the golf stretching training, statistically significant differences were found between the groups in hit-ball driving distance, direction deviation, deflection distance, and speed.

Randomized Controlled Trial Comparing Orthosis Augmented by Either Stretching or Stretching and Strengthening for Stage II Tibialis Posterior Tendon Dysfunction.

PubMed

Houck, Jeff; Neville, Christopher; Tome, Josh; Flemister, Adolph

2015-09-01

The value of strengthening and stretching exercises combined with orthosis treatment in a home-based program has not been evaluated. The purpose of this study was to compare the effects of augmenting orthosis treatment with either stretching or a combination of stretching and strengthening in participants with stage II tibialis posterior tendon dysfunction (TPTD). Participants included 39 patients with stage II TPTD who were recruited from a medical center and then randomly assigned to a strengthening or stretching treatment group. Excluding 3 dropouts, there were 19 participants in the strengthening group and 17 in the stretching group. The stretching treatment consisted of a prefabricated orthosis used in conjunction with stretching exercises. The strengthening treatment consisted of a prefabricated orthosis used in conjunction with the stretching and strengthening exercises. The main outcome measures were self-report (ie, Foot Function Index and Short Musculoskeletal Function Assessment) and isometric deep posterior compartment strength. Two-way analysis of variance was used to test for differences between groups at 6 and 12 weeks after starting the exercise programs. Both groups significantly improved in pain and function over the 12-week trial period. The self-report measures showed minimal differences between the treatment groups. There were no differences in isometric deep posterior compartment strength. A moderate-intensity, home-based exercise program was minimally effective in augmenting orthosis wear alone in participants with stage II TPTD. Level I, prospective randomized study. © The Author(s) 2015.

Three days of intermittent stretching after muscle disuse alters the proteins involved in force transmission in muscle fibers in weanling rats

PubMed Central

Gianelo, M.C.S.; Polizzelo, J.C.; Chesca, D.; Mattiello-Sverzut, A.C.

2015-01-01

The aim of this study was to determine the effects of intermittent passive manual stretching on various proteins involved in force transmission in skeletal muscle. Female Wistar weanling rats were randomly assigned to 5 groups: 2 control groups containing 21- and 30-day-old rats that received neither immobilization nor stretching, and 3 test groups that received 1) passive stretching over 3 days, 2) immobilization for 7 days and then passive stretching over 3 days, or 3) immobilization for 7 days. Maximal plantar flexion in the right hind limb was imposed, and the stretching protocol of 10 repetitions of 30 s stretches was applied. The soleus muscles were harvested and processed for HE and picrosirius staining; immunohistochemical analysis of collagen types I, III, IV, desmin, and vimentin; and immunofluorescence labeling of dystrophin and CD68. The numbers of desmin- and vimentin-positive cells were significantly decreased compared with those in the control following immobilization, regardless of whether stretching was applied (P<0.05). In addition, the semi-quantitative analysis showed that collagen type I was increased and type IV was decreased in the immobilized animals, regardless of whether the stretching protocol was applied. In conclusion, the largest changes in response to stretching were observed in muscles that had been previously immobilized, and the stretching protocol applied here did not mitigate the immobilization-induced muscle changes. Muscle disuse adversely affected several proteins involved in the transmission of forces between the intracellular and extracellular compartments. Thus, the 3-day rehabilitation period tested here did not provide sufficient time for the muscles to recover from the disuse maladaptations in animals undergoing postnatal development. PMID:26648091

Mechanical stretch augments insulin-induced vascular smooth muscle cell proliferation by insulin-like growth factor-1 receptor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Gang; Department of Anesthesiology, First Affiliated Hospital of China Medical University, Shenyang; Hitomi, Hirofumi, E-mail: hitomi@kms.ac.jp

Insulin resistance and hypertension have been implicated in the pathogenesis of cardiovascular disease; however, little is known about the roles of insulin and mechanical force in vascular smooth muscle cell (VSMC) remodeling. We investigated the contribution of mechanical stretch to insulin-induced VSMC proliferation. Thymidine incorporation was stimulated by insulin in stretched VSMCs, but not in un-stretched VSMCs. Insulin increased 2-deoxy-glucose incorporation in both stretched and un-stretched VSMCs. Mechanical stretch augmented insulin-induced extracellular signal-regulated kinase (ERK) and Akt phosphorylation. Inhibitors of epidermal growth factor (EGF) receptor tyrosine kinase and Src attenuated insulin-induced ERK and Akt phosphorylation, as well as thymidine incorporation,more » whereas 2-deoxy-glucose incorporation was not affected by these inhibitors. Moreover, stretch augmented insulin-like growth factor (IGF)-1 receptor expression, although it did not alter the expression of insulin receptor and insulin receptor substrate-1. Insulin-induced ERK and Akt activation, and thymidine incorporation were inhibited by siRNA for the IGF-1 receptor. Mechanical stretch augments insulin-induced VSMC proliferation via upregulation of IGF-1 receptor, and downstream Src/EGF receptor-mediated ERK and Akt activation. Similar to in vitro experiment, IGF-1 receptor expression was also augmented in hypertensive rats. These results provide a basis for clarifying the molecular mechanisms of vascular remodeling in hypertensive patients with hyperinsulinemia. -- Highlights: {yields} Mechanical stretch augments insulin-induced VSMC proliferation via IGF-1 receptor. {yields} Src/EGFR-mediated ERK and Akt phosphorylation are augmented in stretched VSMCs. {yields} Similar to in vitro experiment, IGF-1 receptor is increased in hypertensive rats. {yields} Results provide possible mechanisms of vascular remodeling in hypertension with DM.« less

Effects of two stretching methods on shoulder range of motion and muscle stiffness in baseball players with posterior shoulder tightness: a randomized controlled trial.

PubMed

Yamauchi, Taishi; Hasegawa, Satoshi; Nakamura, Masatoshi; Nishishita, Satoru; Yanase, Ko; Fujita, Kosuke; Umehara, Jun; Ji, Xiang; Ibuki, Satoko; Ichihashi, Noriaki

2016-09-01

The cross-body stretch and sleeper stretch are widely used for improving flexibility of the posterior shoulder. These stretching methods were modified by Wilk. However, few quantitative data are available on the new, modified stretching methods. A recent study reported the immediate effects of stretching and soft tissue mobilization on the shoulder range of motion (ROM) and muscle stiffness in subjects with posterior shoulder tightness. However, the long-term effect of stretching for muscle stiffness is unknown. The objective of this study was to examine the effects of 2 stretching methods, the modified cross-body stretch (MCS) and the modified sleeper stretch (MSS), on shoulder ROM and muscle stiffness in baseball players with posterior shoulder tightness. Twenty-four college baseball players with ROM limitations in shoulder internal rotation were randomly assigned to the MCS or MSS group. We measured shoulder internal rotation and horizontal adduction ROM and assessed posterior shoulder muscle stiffness with ultrasonic shear wave elastography before and after a 4-week intervention. Subjects were asked to perform 3 repetitions of the stretching exercises every day, for 30 seconds, with their dominant shoulder. In both groups, shoulder internal rotation and horizontal adduction ROM were significantly increased after the 4-week intervention. Muscle stiffness of the teres minor decreased in the MCS group, and that of the infraspinatus decreased in the MSS group. The MCS and MSS are effective for increasing shoulder internal rotation and horizontal adduction ROM and decreasing muscle stiffness of the infraspinatus or teres minor. Copyright © 2016 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

Local and Systemic Changes in Pain Sensitivity After 4 Weeks of Calf Muscle Stretching in a Nonpainful Population: A Randomized Trial.

PubMed

Bartholdy, Cecilie; Zangger, Graziella; Hansen, Lisbeth; Ginnerup-Nielsen, Elisabeth; Bliddal, Henning; Henriksen, Marius

2016-07-01

Stretching is often used in clinical practice for a variety of purposes, including pain therapy. The possible mechanism behind the effect of stretching remains to be clarified. To investigate whether 4 weeks of unilateral stretching of the calf muscles would affect local and central pain sensitivity. This study was a randomized assessor-blinded clinical study. Healthy participants (age 18 to 40) were included and randomized. Participants in the intervention group were instructed to perform 2 stretching exercises targeting the calf muscles; 3 times 30 seconds, 7 days a week for 4 weeks on the dominant leg. Participants in the control group were instructed not to do any stretching for 4 weeks. Pressure pain threshold (PPT) and temporal summation (TS) of pressure pain were measured on the stretched calf, the contra-lateral calf, and contra-lateral lower arm using a computerized cuff algometer. Analyses of variance on the per-protocol population (defined as participants that adhered to the protocol) were used to assess group differences in the changes from baseline. Forty healthy volunteers were included, of which 34 participants adhered to the protocol (15 intervention group/19 control group). No statistically significant group differences in the changes from baseline were found regarding PPT and TS measurements for the stretched calf, the contra-lateral calf, and the arm. Four weeks of regular stretching of the calf muscles does not affect pressure pain sensitivity, suggesting that pressure pain sensitivity is unaffected by stretching in a healthy population. The mechanisms underlying any benefits of regular stretching remain to be explained. © 2015 World Institute of Pain.

Three days of intermittent stretching after muscle disuse alters the proteins involved in force transmission in muscle fibers in weanling rats.

PubMed

Gianelo, M C S; Polizzelo, J C; Chesca, D; Mattiello-Sverzut, A C

2016-02-01

The aim of this study was to determine the effects of intermittent passive manual stretching on various proteins involved in force transmission in skeletal muscle. Female Wistar weanling rats were randomly assigned to 5 groups: 2 control groups containing 21- and 30-day-old rats that received neither immobilization nor stretching, and 3 test groups that received 1) passive stretching over 3 days, 2) immobilization for 7 days and then passive stretching over 3 days, or 3) immobilization for 7 days. Maximal plantar flexion in the right hind limb was imposed, and the stretching protocol of 10 repetitions of 30 s stretches was applied. The soleus muscles were harvested and processed for HE and picrosirius staining; immunohistochemical analysis of collagen types I, III, IV, desmin, and vimentin; and immunofluorescence labeling of dystrophin and CD68. The numbers of desmin- and vimentin-positive cells were significantly decreased compared with those in the control following immobilization, regardless of whether stretching was applied (P<0.05). In addition, the semi-quantitative analysis showed that collagen type I was increased and type IV was decreased in the immobilized animals, regardless of whether the stretching protocol was applied. In conclusion, the largest changes in response to stretching were observed in muscles that had been previously immobilized, and the stretching protocol applied here did not mitigate the immobilization-induced muscle changes. Muscle disuse adversely affected several proteins involved in the transmission of forces between the intracellular and extracellular compartments. Thus, the 3-day rehabilitation period tested here did not provide sufficient time for the muscles to recover from the disuse maladaptations in animals undergoing postnatal development.

Secondary structure estimation and properties analysis of stretched Asian and Caucasian hair.

PubMed

Zhou, A J; Liu, H L; Du, Z Q

2015-02-01

In this previous work, we investigated the secondary structure changes of stretched yak hairs by deconvolution, secondary derivation, and curve fitting and determined the number of bands and their positions in order to resolve the protein spectrum of Raman spectroscopy. The secondary structure estimation and properties analysis of stretched Asian and Caucasian hair were investigated by Fourier transform infrared spectroscopy, tensile curves, and measurement of density. The hairs were stretched, dried, and baked at ratios 20%, 40%, 60%, 80% and 100%. The analysis of the amide I band indicated that the transformation from α-helix to β-pleated structure occurred during the stretching process, which could be verified from the tensile analysis. The cysteine oxide in S-O vibration area exhibited that stretching led to the breakage of the disulfide bonds. When the stretching ratio of Caucasian hair was more than a certain ratio, the fiber macromolecular structure was destroyed because Caucasian hair had finer diameter and less medulla than Asian hair. The β turn was easier to retract compared with other conformations, resulted in the content increase. The density measurements revealed that the structure of Caucasian hair was indeed more destroyed than that of Asian hair. The cuticles characterization indicated the length of scales was stretched longer and the thickness became thinner. Caucasian hair tended to collapse to form small fragments at the early stage of stretching. With the increase in stretching ratio, the scales of Caucasian hair lifted up, then flaked off and the scale interval increased accordingly. Asian hair was more easily peeled off than Caucasian hair cuticles with the increase in stretching ratio. The secondary structure of Caucasian hair was destroyed more easily than that of Asian hair. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Reduced IL-10 Production in Fetal Type II Epithelial Cells Exposed to Mechanical Stretch Is Mediated via Activation of IL-6-SOCS3 Signaling Pathway

PubMed Central

Hawwa, Renda L.; Huang, Zheping; Sharma, Surendra; Sanchez-Esteban, Juan

2013-01-01

An imbalance between pro-inflammatory and anti-inflammatory cytokines is a key factor in the lung injury of premature infants exposed to mechanical ventilation. Previous studies have shown that lung cells exposed to stretch produces reduced amounts of the anti-inflammatory cytokine IL-10. The objective of these studies was to analyze the signaling mechanisms responsible for the decreased IL-10 production in fetal type II cells exposed to mechanical stretch. Fetal mouse type II epithelial cells isolated at embryonic day 18 were exposed to 20% stretch to simulate lung injury. We show that IL-10 receptor gene expression increased with gestational age. Mechanical stretch decreased not only IL-10 receptor gene expression but also IL-10 secretion. In contrast, mechanical stretch increased release of IL-6. We then investigated IL-10 signaling pathway-associated proteins and found that in wild-type cells, mechanical stretch decreased activation of JAK1 and TYK2 and increased STAT3 and SOCS3 activation. However, opposite effects were found in cells isolated from IL-10 knockout mice. Reduction in IL-6 secretion by stretch was observed in cells isolated from IL-10 null mice. To support the idea that stretch-induced SOCS3 expression via IL-6 leads to reduced IL-10 expression, siRNA-mediated inhibition of SOCS3 restored IL-10 secretion in cells exposed to stretch and decreased IL-6 secretion. Taken together, these studies suggest that the inhibitory effect of mechanical stretch on IL-10 secretion is mediated via activation of IL-6-STAT3-SOCS3 signaling pathway. SOCS3 could be a therapeutic target to increase IL-10 production in lung cells exposed to mechanical injury. PMID:23527226

Reduced IL-10 production in fetal type II epithelial cells exposed to mechanical stretch is mediated via activation of IL-6-SOCS3 signaling pathway.

PubMed

Hokenson, Michael A; Wang, Yulian; Hawwa, Renda L; Huang, Zheping; Sharma, Surendra; Sanchez-Esteban, Juan

2013-01-01

An imbalance between pro-inflammatory and anti-inflammatory cytokines is a key factor in the lung injury of premature infants exposed to mechanical ventilation. Previous studies have shown that lung cells exposed to stretch produces reduced amounts of the anti-inflammatory cytokine IL-10. The objective of these studies was to analyze the signaling mechanisms responsible for the decreased IL-10 production in fetal type II cells exposed to mechanical stretch. Fetal mouse type II epithelial cells isolated at embryonic day 18 were exposed to 20% stretch to simulate lung injury. We show that IL-10 receptor gene expression increased with gestational age. Mechanical stretch decreased not only IL-10 receptor gene expression but also IL-10 secretion. In contrast, mechanical stretch increased release of IL-6. We then investigated IL-10 signaling pathway-associated proteins and found that in wild-type cells, mechanical stretch decreased activation of JAK1 and TYK2 and increased STAT3 and SOCS3 activation. However, opposite effects were found in cells isolated from IL-10 knockout mice. Reduction in IL-6 secretion by stretch was observed in cells isolated from IL-10 null mice. To support the idea that stretch-induced SOCS3 expression via IL-6 leads to reduced IL-10 expression, siRNA-mediated inhibition of SOCS3 restored IL-10 secretion in cells exposed to stretch and decreased IL-6 secretion. Taken together, these studies suggest that the inhibitory effect of mechanical stretch on IL-10 secretion is mediated via activation of IL-6-STAT3-SOCS3 signaling pathway. SOCS3 could be a therapeutic target to increase IL-10 production in lung cells exposed to mechanical injury.

Effect of Ankle Positioning During Hamstring Stretches for Improving Straight Leg Hip Flexion Motion.

PubMed

Laudner, Kevin G; Benjamin, Peter J; Selkow, Noelle M

2016-03-01

To compare the effects of stretching the hamstrings with the ankle in either a plantar-flexed (PF) or dorsiflexed (DF) position for improving straight leg hip flexion range of motion (ROM) over a 4-week period. Randomized, single-blinded, pretest, posttest design. Athletic training facility. Each limb of 34 asymptomatic individuals (15 males, 19 females) was randomly assigned to one of the 3 groups. Twenty-four limbs received hamstring stretches with the ankle in DF, 24 limbs received hamstring stretches with the ankle in PF, and 20 limbs received no stretch (control). Ankle position (PF, DF) during hamstring stretching. We measured pretest and posttest passive straight leg hip flexion ROM with the test ankle in a neutral position. For the intervention groups, the test limb was passively stretched with the ankle held in end range DF or PF for their respective group. Each stretch was held for 30 seconds for a total of 3 applications. Two treatment sessions were completed per week for a total of 4 weeks. The control limbs received no stretching during the 4-week period. We conducted 1-way analyses of covariance to determine significant changes in ROM between groups (P < 0.05). There was no significant difference between treatment groups (P = 0.90), but a significant difference was found for both the PF (P = 0.04) and DF (P = 0.01) groups when compared with the control group. Our findings indicate that both stretching the hamstrings in either PF or DF improve straight leg hip ROM compared with a control group. The results of this study should be considered by clinicians when determining the optimal stretching techniques aimed at increasing hamstring length.

An examination of the stretching practices of Division I and Division III college football programs in the midwestern United States.

PubMed

Judge, Lawrence W; Craig, Bruce; Baudendistal, Steve; Bodey, Kimberly J

2009-07-01

Research supports the use of preactivity warm-up and stretching, and the purpose of this study was to determine whether college football programs follow these guidelines. Questionnaires designed to gather demographic, professional, and educational information, as well as specific pre- and postactivity practices, were distributed via e-mail to midwestern collegiate programs from NCAA Division I and III conferences. Twenty-three male coaches (12 from Division IA schools and 11 from Division III schools) participated in the study. Division I schools employed certified strength coaches (CSCS; 100%), whereas Division III schools used mainly strength coordinators (73%), with only 25% CSCS. All programs used preactivity warm-up, with the majority employing 2-5 minutes of sport-specific jogging/running drills. Pre stretching (5-10 minutes) was performed in 19 programs (91%), with 2 (9%) performing no pre stretching. Thirteen respondents used a combination of static/proprioceptive neuromuscular facilitation/ballistic and dynamic flexibility, 5 used only dynamic flexibility, and 1 used only static stretching. All 12 Division I coaches used stretching, whereas only 9 of the 11 Division III coaches did (p = 0.22). The results indicate that younger coaches did not use pre stretching (p = 0.30). The majority of the coaches indicated that they did use post stretching, with 11 of the 12 Division I coaches using stretching, whereas only 5 of the 11 Division III coaches used stretching postactivity (p = 0.027). Divisional results show that the majority of Division I coaches use static-style stretching (p = 0.049). The results of this study indicate that divisional status, age, and certification may influence how well research guidelines are followed. Further research is needed to delineate how these factors affect coaching decisions.

Parameterized spectral distributions for meson production in proton-proton collisions

NASA Technical Reports Server (NTRS)

Schneider, John P.; Norbury, John W.; Cucinotta, Francis A.

1995-01-01

Accurate semiempirical parameterizations of the energy-differential cross sections for charged pion and kaon production from proton-proton collisions are presented at energies relevant to cosmic rays. The parameterizations, which depend on both the outgoing meson parallel momentum and the incident proton kinetic energy, are able to be reduced to very simple analytical formulas suitable for cosmic ray transport through spacecraft walls, interstellar space, the atmosphere, and meteorites.

Implementation of a Parameterization Framework for Cybersecurity Laboratories

DTIC Science & Technology

2017-03-01

designer of laboratory exercises with tools to parameterize labs for each student , and automate some aspects of the grading of laboratory exercises. A...is to provide the designer of laboratory exercises with tools to parameterize labs for each student , and automate some aspects of the grading of...support might assist the designer of laboratory exercises to achieve the following? 1. Verify that students performed lab exercises, with some

Relativistic three-dimensional Lippmann-Schwinger cross sections for space radiation applications

NASA Astrophysics Data System (ADS)

Werneth, C. M.; Xu, X.; Norman, R. B.; Maung, K. M.

2017-12-01

Radiation transport codes require accurate nuclear cross sections to compute particle fluences inside shielding materials. The Tripathi semi-empirical reaction cross section, which includes over 60 parameters tuned to nucleon-nucleus (NA) and nucleus-nucleus (AA) data, has been used in many of the world's best-known transport codes. Although this parameterization fits well to reaction cross section data, the predictive capability of any parameterization is questionable when it is used beyond the range of the data to which it was tuned. Using uncertainty analysis, it is shown that a relativistic three-dimensional Lippmann-Schwinger (LS3D) equation model based on Multiple Scattering Theory (MST) that uses 5 parameterizations-3 fundamental parameterizations to nucleon-nucleon (NN) data and 2 nuclear charge density parameterizations-predicts NA and AA reaction cross sections as well as the Tripathi cross section parameterization for reactions in which the kinetic energy of the projectile in the laboratory frame (TLab) is greater than 220 MeV/n. The relativistic LS3D model has the additional advantage of being able to predict highly accurate total and elastic cross sections. Consequently, it is recommended that the relativistic LS3D model be used for space radiation applications in which TLab > 220MeV /n .

How to assess the impact of a physical parameterization in simulations of moist convection?

NASA Astrophysics Data System (ADS)

Grabowski, Wojciech

2017-04-01

A numerical model capable in simulating moist convection (e.g., cloud-resolving model or large-eddy simulation model) consists of a fluid flow solver combined with required representations (i.e., parameterizations) of physical processes. The later typically include cloud microphysics, radiative transfer, and unresolved turbulent transport. Traditional approaches to investigate impacts of such parameterizations on convective dynamics involve parallel simulations with different parameterization schemes or with different scheme parameters. Such methodologies are not reliable because of the natural variability of a cloud field that is affected by the feedback between the physics and dynamics. For instance, changing the cloud microphysics typically leads to a different realization of the cloud-scale flow, and separating dynamical and microphysical impacts is difficult. This presentation will present a novel modeling methodology, the piggybacking, that allows studying the impact of a physical parameterization on cloud dynamics with confidence. The focus will be on the impact of cloud microphysics parameterization. Specific examples of the piggybacking approach will include simulations concerning the hypothesized deep convection invigoration in polluted environments, the validity of the saturation adjustment in modeling condensation in moist convection, and separation of physical impacts from statistical uncertainty in simulations applying particle-based Lagrangian microphysics, the super-droplet method.

Stretch-induced, steady-state force enhancement in single skeletal muscle fibers exceeds the isometric force at optimum fiber length.

PubMed

Rassier, Dilson E; Herzog, Walter; Wakeling, Jennifer; Syme, Douglas A

2003-09-01

Stretch-induced force enhancement has been observed in a variety of muscle preparations and on structural levels ranging from single fibers to in vivo human muscles. It is a well-accepted property of skeletal muscle. However, the mechanism causing force enhancement has not been elucidated, although the sarcomere-length non-uniformity theory has received wide support. The purpose of this paper was to re-investigate stretch-induced force enhancement in frog single fibers by testing specific hypotheses arising from the sarcomere-length non-uniformity theory. Single fibers dissected from frog tibialis anterior (TA) and lumbricals (n=12 and 22, respectively) were mounted in an experimental chamber with physiological Ringer's solution (pH=7.5) between a force transducer and a servomotor length controller. The tetantic force-length relationship was determined. Isometric reference forces were determined at optimum length (corresponding to the maximal, active, isometric force), and at the initial and final lengths of the stretch experiments. Stretch experiments were performed on the descending limb of the force-length relationship after maximal tetanic force was reached. Stretches of 2.5-10% (TA) and 5-15% lumbricals of fiber length were performed at 0.1-1.5 fiber lengths/s. The stretch-induced, steady-state, active isometric force was always equal or greater than the purely isometric force at the muscle length from which the stretch was initiated. Moreover, for stretches of 5% fiber length or greater, and initiated near the optimum length of the fiber, the stretch-enhanced active force always exceeded the maximal active isometric force at optimum length. Finally, we observed a stretch-induced enhancement of passive force. We conclude from these results that the sarcomere length non-uniformity theory alone cannot explain the observed force enhancement, and that part of the force enhancement is associated with a passive force that is substantially greater after active compared to passive muscle stretch.

Crustal Stretching Style and Lower Crust Flow of the South China Sea Northern Margin

NASA Astrophysics Data System (ADS)

Bai, Y.; Dong, D.; Runlin, D.

2017-12-01

There is a controversy about crustal stretching style of the South China Sea (SCS) northern margin mainly due to considerable uncertainty of stretching factor estimation, for example, as much as 40% of upper crust extension (Walsh et al., 1991) would be lost by seismic profiles due to poor resolution. To discover and understand crustal stretching style and lower crustal flow on the whole, we map the Moho and Conrad geometries based on gravity inversion constrained by deep seismic profiles, then according to the assumption of upper and lower crust initial thickness, upper and lower crust stretching factors are estimated. According to the comparison between upper and lower crust stretching factors, the SCS northern margin could be segmented into three parts, (1) sediment basins where upper crust is stretched more than lower crust, (2) COT regions where lower crust is stretched more than upper crust, (3) other regions where the two layers have similar stretching factors. Stretching factor map shows that lower crust flow happened in both of COT and sediment basin regions where upper crust decouples with lower crust due to high temperature. Pressure contrast by sediment loading in basins and erosion in sediment-source regions will lead to lower crust flow away from sediment sink to source. Decoupled and fractured upper crust is stretched further by sediment loading and the following compensation would result in relatively thick lower crust than upper crust. In COT regions with thin sediment coverage, low-viscosity lower crust is easier to thin in extensional environment, also the lower crust tends to flow away induced by magma upwelling. Therefore, continental crust on the margin is not stretching in a constant way but varies with the tectonic setting changes. This work is supported by National Natural Science Foundation of China (Grant No. 41506055, 41476042) and Fundamental Research Funds for the Central Universities China (No.17CX02003A).

The Effects of Different Passive Static Stretching Intensities on Recovery from Unaccustomed Eccentric Exercise - A Randomized Controlled Trial.

PubMed

Apostolopoulos, Nikos C; Lahart, Ian M; Plyley, Michael J; Taunton, Jack; Nevill, Alan M; Koutedakis, Yiannis; Wyon, Matthew; Metsios, George S

2018-03-12

Effects of passive static stretching intensity on recovery from unaccustomed eccentric exercise of right knee extensors was investigated in 30 recreationally active males randomly allocated into three groups: high-intensity (70-80% maximum perceived stretch), low-intensity (30-40% maximum perceived stretch), and control. Both stretching groups performed 3 sets of passive static stretching exercises of 60s each for hamstrings, hip flexors, and quadriceps, over 3 consecutive days, post-unaccustomed eccentric exercise. Muscle function (eccentric and isometric peak torque) and blood biomarkers (CK and CRP) were measured before (baseline) and after (24, 48, and 72h) unaccustomed eccentric exercise. Perceived muscle soreness scores were collected immediately (time 0), and after 24, 48, and 72h post-exercise. Statistical time x condition interactions observed only for eccentric peak torque (p=.008). Magnitude-based inference analyses revealed low-intensity stretching had most likely, very likely, or likely beneficial effects on perceived muscle soreness (48-72h and 0-72h) and eccentric peak torque (baseline-24h and baseline-72h), compared with high-intensity stretching. Compared with control, low-intensity stretching had very likely or likely beneficial effects on perceived muscle soreness (0-24h and 0-72h), eccentric peak torque (baseline-48h and baseline-72h), and isometric peak torque (baseline-72h). High-intensity stretching had likely beneficial effects on eccentric peak torque (baseline-48h), but likely harmful effects eccentric peak torque (baseline-24h) and CK (baseline-48h and baseline-72h), compared with control. Therefore, low-intensity stretching is likely to result in small-to-moderate beneficial effects on perceived muscle soreness and recovery of muscle function post-unaccustomed eccentric exercise, but not markers of muscle damage and inflammation, compared with high-intensity or no stretching.

Weak depth and along-strike variations in stretching from a multi-episodic finite stretching model: Evidence for uniform pure-shear extension in the opening of the South China Sea

NASA Astrophysics Data System (ADS)

Chen, Lin; Zhang, Zhongjie; Song, Haibin

2013-12-01

The South China Sea is widely believed to have been opened by seafloor spreading during the Cenozoic. The details of its lithospheric extension are still being debated, and it is unknown whether pure, simple, or conjunct shears are responsible for the opening of the South China Sea. The depth-dependent and along-strike extension derived from the single-stage finite stretching model or instantaneous stretching model is inconsistent with the observation that the South China Sea proto-margins have experienced multi-episodic extension since the Late Cretaceous. Based on the multi-episodic finite stretching model, we present the amount of lithosphere stretching at the northern continental margin of the South China Sea for different depth scales (upper crust, whole crust and lithosphere) and along several transects. The stretching factors are estimated by integrating seven deep-penetration seismic profiles, the Moho distribution derived from gravity modeling, and the tectonic subsidence data for 41 wells. The results demonstrate that the amount of stretching increases rapidly from 1.1 at the continent shelf to over 3.5 at the lower slope, but the stretching factors at the crust and lithosphere scales are consistent within error (from the uncertainty in paleobathymetry and sea-level change). Furthermore, the along-strike variation in stretching factor is within the range of 1.11-1.9 in west-east direction, accompanied by significant west-east differences in the thickness of high-velocity layers (HVLs) within the lowermost crust. This weak along-strike variation of the stretching factor is most likely produced by the preexisting contrasts in the composition and thermal structure of the lithosphere. The above observations suggest that the continental extension in the opening of the South China Sea mainly takes the form of a uniform pure shear rather than depth-dependent stretching.

Active shortening protects against stretch-induced force deficits in human skeletal muscle.

PubMed

Saripalli, Anjali L; Sugg, Kristoffer B; Mendias, Christopher L; Brooks, Susan V; Claflin, Dennis R

2017-05-01

Skeletal muscle contraction results from molecular interactions of myosin "crossbridges" with adjacent actin filament binding sites. The binding of myosin to actin can be "weak" or "strong," and only strong binding states contribute to force production. During active shortening, the number of strongly bound crossbridges declines with increasing shortening velocity. Forcibly stretching a muscle that is actively shortening at high velocity results in no apparent negative consequences, whereas stretch of an isometrically (fixed-length) contracting muscle causes ultrastructural damage and a decline in force-generating capability. Our working hypothesis is that stretch-induced damage is uniquely attributable to the population of crossbridges that are strongly bound. We tested the hypothesis that stretch-induced force deficits decline as the prevailing shortening velocity is increased. Experiments were performed on permeabilized segments of individual skeletal muscle fibers obtained from human subjects. Fibers were maximally activated and allowed either to generate maximum isometric force (F o ), or to shorten at velocities that resulted in force maintenance of ≈50% F o or ≈2% F o For each test condition, a rapid stretch equivalent to 0.1 × optimal fiber length was applied. Relative to prestretch F o , force deficits resulting from stretches applied during force maintenance of 100, ≈50, and ≈2% F o were 23.2 ± 8.6, 7.8 ± 4.2, and 0.3 ± 3.3%, respectively (means ± SD, n = 20). We conclude that stretch-induced damage declines with increasing shortening velocity, consistent with the working hypothesis that the fraction of strongly bound crossbridges is a causative factor in the susceptibility of skeletal muscle to stretch-induced damage. NEW & NOTEWORTHY Force deficits caused by stretch of contracting muscle are most severe when the stretch is applied during an isometric contraction, but prevented if the muscle is shortening at high velocity when the stretch occurs. This study indicates that velocity-controlled modulation of the number of strongly bound crossbridges is the basis for the observed relationship between stretch-induced muscle damage and prevailing shortening velocity. Copyright © 2017 the American Physiological Society.

Acute effects of static stretching on peak and end-range hamstring-to-quadriceps functional ratios.

PubMed

Sekir, Ufuk; Arabaci, Ramiz; Akova, Bedrettin

2015-10-18

To evaluate if static stretching influences peak and end-range functional hamstring-to-quadriceps (H/Q) strength ratios in elite women athletes. Eleven healthy female athletes in an elite competitive level participated to the study. All the participants fulfilled the static stretching or non-stretching (control) intervention protocol in a randomized design on different days. Two static unassisted stretching exercises, one in standing and one in sitting position, were used to stretch both the hamstring and quadriceps muscles during these protocols. The total time for the static stretching was 6 ± 1 min. The isokinetic peak torque measurements for the hamstring and quadriceps muscles in eccentric and concentric modes and the calculations for the functional H/Q strength ratios at angular velocities of 60°/s and 180°/s were made before (pre) and after (post) the control or stretching intervention. The strength measurements and functional strength ratio calculations were based during the entire- and end-range of knee extension. The pre-test scores for quadriceps and hamstring peak torque and end range values were not significantly different between the groups (P > 0.05). Subsequently, although the control group did not exhibit significant changes in quadriceps and hamstring muscle strength (P > 0.05), static stretching decreased eccentric and concentric quadriceps muscle strength at both the 60°/s and 180°/s test speeds (P < 0.01). Similarly, static stretching also decreased eccentric and concentric hamstring muscle strength at both the 60°/s and 180°/s test speeds (P < 0.01). On the other hand, when the functional H/Q strength ratios were taken into consideration, the pre-intervention values were not significant different between the groups both during the entire and end range of knee extension (P > 0.05). Furthermore, the functional H/Q strength ratios exhibited no significant alterations during the entire and end ranges of knee extension both in the static stretching or the control intervention (P > 0.05). According to our results, static stretching routine does not influence functional H/Q ratio. Athletes can confidently perform static stretching during their warm-up routines.

Active shortening protects against stretch-induced force deficits in human skeletal muscle

PubMed Central

Saripalli, Anjali L.; Sugg, Kristoffer B.; Brooks, Susan V.

2017-01-01

Skeletal muscle contraction results from molecular interactions of myosin “crossbridges” with adjacent actin filament binding sites. The binding of myosin to actin can be “weak” or “strong,” and only strong binding states contribute to force production. During active shortening, the number of strongly bound crossbridges declines with increasing shortening velocity. Forcibly stretching a muscle that is actively shortening at high velocity results in no apparent negative consequences, whereas stretch of an isometrically (fixed-length) contracting muscle causes ultrastructural damage and a decline in force-generating capability. Our working hypothesis is that stretch-induced damage is uniquely attributable to the population of crossbridges that are strongly bound. We tested the hypothesis that stretch-induced force deficits decline as the prevailing shortening velocity is increased. Experiments were performed on permeabilized segments of individual skeletal muscle fibers obtained from human subjects. Fibers were maximally activated and allowed either to generate maximum isometric force (Fo), or to shorten at velocities that resulted in force maintenance of ≈50% Fo or ≈2% Fo. For each test condition, a rapid stretch equivalent to 0.1 × optimal fiber length was applied. Relative to prestretch Fo, force deficits resulting from stretches applied during force maintenance of 100, ≈50, and ≈2% Fo were 23.2 ± 8.6, 7.8 ± 4.2, and 0.3 ± 3.3%, respectively (means ± SD, n = 20). We conclude that stretch-induced damage declines with increasing shortening velocity, consistent with the working hypothesis that the fraction of strongly bound crossbridges is a causative factor in the susceptibility of skeletal muscle to stretch-induced damage. NEW & NOTEWORTHY Force deficits caused by stretch of contracting muscle are most severe when the stretch is applied during an isometric contraction, but prevented if the muscle is shortening at high velocity when the stretch occurs. This study indicates that velocity-controlled modulation of the number of strongly bound crossbridges is the basis for the observed relationship between stretch-induced muscle damage and prevailing shortening velocity. PMID:28235860

Acute effects of static stretching on peak and end-range hamstring-to-quadriceps functional ratios

PubMed Central

Sekir, Ufuk; Arabaci, Ramiz; Akova, Bedrettin

2015-01-01

AIM: To evaluate if static stretching influences peak and end-range functional hamstring-to-quadriceps (H/Q) strength ratios in elite women athletes. METHODS: Eleven healthy female athletes in an elite competitive level participated to the study. All the participants fulfilled the static stretching or non-stretching (control) intervention protocol in a randomized design on different days. Two static unassisted stretching exercises, one in standing and one in sitting position, were used to stretch both the hamstring and quadriceps muscles during these protocols. The total time for the static stretching was 6 ± 1 min. The isokinetic peak torque measurements for the hamstring and quadriceps muscles in eccentric and concentric modes and the calculations for the functional H/Q strength ratios at angular velocities of 60°/s and 180°/s were made before (pre) and after (post) the control or stretching intervention. The strength measurements and functional strength ratio calculations were based during the entire- and end-range of knee extension. RESULTS: The pre-test scores for quadriceps and hamstring peak torque and end range values were not significantly different between the groups (P > 0.05). Subsequently, although the control group did not exhibit significant changes in quadriceps and hamstring muscle strength (P > 0.05), static stretching decreased eccentric and concentric quadriceps muscle strength at both the 60°/s and 180°/s test speeds (P < 0.01). Similarly, static stretching also decreased eccentric and concentric hamstring muscle strength at both the 60°/s and 180°/s test speeds (P < 0.01). On the other hand, when the functional H/Q strength ratios were taken into consideration, the pre-intervention values were not significant different between the groups both during the entire and end range of knee extension (P > 0.05). Furthermore, the functional H/Q strength ratios exhibited no significant alterations during the entire and end ranges of knee extension both in the static stretching or the control intervention (P > 0.05). CONCLUSION: According to our results, static stretching routine does not influence functional H/Q ratio. Athletes can confidently perform static stretching during their warm-up routines. PMID:26495249

The purinergic component of human bladder smooth muscle cells’ proliferation and contraction under physiological stretch

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wazir, Romel; Luo, De-Yi; Tian, Ye

Highlights: •Stretch induces proliferation and contraction. •Optimum applied stretch in vitro is 5% and 10% equibiaxial stretching respectively. •Expression of P2X1 and P2X2 is upregulated after application of stretch. •P2X2 is possibly more susceptible to stretch related changes. •Purinoceptors functioning may explain conditions with atropine resistance. -- Abstract: Objective: To investigate whether cyclic stretch induces proliferation and contraction of human smooth muscle cells (HBSMCs), mediated by P2X purinoceptor 1 and 2 and the signal transduction mechanisms of this process. Methods: HBSMCs were seeded on silicone membrane and stretched under varying parameters; (equibiaxial elongation: 2.5%, 5%, 10%, 15%, 20%, 25%), (Frequency:more » 0.05 Hz, 0.1 Hz, 0.2 Hz, 0.5 Hz, 1 Hz). 5-Bromo-2-deoxyuridine assay was employed for proliferative studies. Contractility of the cells was determined using collagen gel contraction assay. After optimal physiological stretch was established; P2X1 and P2X2 were analyzed by real time polymerase chain reaction and Western Blot. Specificity of purinoceptors was maintained by employing specific inhibitors; (NF023 for P2X1, and A317491for P2X2), in some experiments. Results: Optimum proliferation and contractility were observed at 5% and 10% equibiaxial stretching respectively, applied at a frequency of 0.1 Hz; At 5% stretch, proliferation increased from 0.837 ± 0.026 (control) to 1.462 ± 0.023%, p < 0.05. Mean contraction at 10% stretching increased from 31.7 ± 2.3%, (control) to 78.28 ±1.45%, p < 0.05. Expression of P2X1 and P2X2 was upregulated after application of stretch. Inhibition had effects on proliferation (1.232 ± 0.051, p < 0.05 NF023) and (1.302 ± 0.021, p < 0.05 A314791) while contractility was markedly reduced (68.24 ± 2.31, p < 0.05 NF023) and (73.2 ± 2.87, p < 0.05 A314791). These findings shows that mechanical stretch can promote magnitude-dependent proliferative and contractile modulation of HBSMCs in vitro, and P2X1 and 2 are at least partially responsible in this process.« less

Sensitivity of Cirrus and Mixed-phase Clouds to the Ice Nuclei Spectra in McRAS-AC: Single Column Model Simulations

NASA Technical Reports Server (NTRS)

Betancourt, R. Morales; Lee, D.; Oreopoulos, L.; Sud, Y. C.; Barahona, D.; Nenes, A.

2012-01-01

The salient features of mixed-phase and ice clouds in a GCM cloud scheme are examined using the ice formation parameterizations of Liu and Penner (LP) and Barahona and Nenes (BN). The performance of LP and BN ice nucleation parameterizations were assessed in the GEOS-5 AGCM using the McRAS-AC cloud microphysics framework in single column mode. Four dimensional assimilated data from the intensive observation period of ARM TWP-ICE campaign was used to drive the fluxes and lateral forcing. Simulation experiments where established to test the impact of each parameterization in the resulting cloud fields. Three commonly used IN spectra were utilized in the BN parameterization to described the availability of IN for heterogeneous ice nucleation. The results show large similarities in the cirrus cloud regime between all the schemes tested, in which ice crystal concentrations were within a factor of 10 regardless of the parameterization used. In mixed-phase clouds there are some persistent differences in cloud particle number concentration and size, as well as in cloud fraction, ice water mixing ratio, and ice water path. Contact freezing in the simulated mixed-phase clouds contributed to transfer liquid to ice efficiently, so that on average, the clouds were fully glaciated at T approximately 260K, irrespective of the ice nucleation parameterization used. Comparison of simulated ice water path to available satellite derived observations were also performed, finding that all the schemes tested with the BN parameterization predicted 20 average values of IWP within plus or minus 15% of the observations.

Impacts of subgrid-scale orography parameterization on simulated atmospheric fields over Korea using a high-resolution atmospheric forecast model

NASA Astrophysics Data System (ADS)

Lim, Kyo-Sun Sunny; Lim, Jong-Myoung; Shin, Hyeyum Hailey; Hong, Jinkyu; Ji, Young-Yong; Lee, Wanno

2018-06-01

A substantial over-prediction bias at low-to-moderate wind speeds in the Weather Research and Forecasting (WRF) model has been reported in the previous studies. Low-level wind fields play an important role in dispersion of air pollutants, including radionuclides, in a high-resolution WRF framework. By implementing two subgrid-scale orography parameterizations (Jimenez and Dudhia in J Appl Meteorol Climatol 51:300-316, 2012; Mass and Ovens in WRF model physics: problems, solutions and a new paradigm for progress. Preprints, 2010 WRF Users' Workshop, NCAR, Boulder, Colo. http://www.mmm.ucar.edu/wrf/users/workshops/WS2010/presentations/session%204/4-1_WRFworkshop2010Final.pdf, 2010), we tried to compare the performance of parameterizations and to enhance the forecast skill of low-level wind fields over the central western part of South Korea. Even though both subgrid-scale orography parameterizations significantly alleviated the positive bias at 10-m wind speed, the parameterization by Jimenez and Dudhia revealed a better forecast skill in wind speed under our modeling configuration. Implementation of the subgrid-scale orography parameterizations in the model did not affect the forecast skills in other meteorological fields including 10-m wind direction. Our study also brought up the problem of discrepancy in the definition of "10-m" wind between model physics parameterizations and observations, which can cause overestimated winds in model simulations. The overestimation was larger in stable conditions than in unstable conditions, indicating that the weak diurnal cycle in the model could be attributed to the representation error.

Finescale parameterizations of energy dissipation in a region of strong internal tides and sheared flow, the Lucky-Strike segment of the Mid-Atlantic Ridge

NASA Astrophysics Data System (ADS)

Pasquet, Simon; Bouruet-Aubertot, Pascale; Reverdin, Gilles; Turnherr, Andreas; Laurent, Lou St.

2016-06-01

The relevance of finescale parameterizations of dissipation rate of turbulent kinetic energy is addressed using finescale and microstructure measurements collected in the Lucky Strike segment of the Mid-Atlantic Ridge (MAR). There, high amplitude internal tides and a strongly sheared mean flow sustain a high level of dissipation rate and turbulent mixing. Two sets of parameterizations are considered: the first ones (Gregg, 1989; Kunze et al., 2006) were derived to estimate dissipation rate of turbulent kinetic energy induced by internal wave breaking, while the second one aimed to estimate dissipation induced by shear instability of a strongly sheared mean flow and is a function of the Richardson number (Kunze et al., 1990; Polzin, 1996). The latter parameterization has low skill in reproducing the observed dissipation rate when shear unstable events are resolved presumably because there is no scale separation between the duration of unstable events and the inverse growth rate of unstable billows. Instead GM based parameterizations were found to be relevant although slight biases were observed. Part of these biases result from the small value of the upper vertical wavenumber integration limit in the computation of shear variance in Kunze et al. (2006) parameterization that does not take into account internal wave signal of high vertical wavenumbers. We showed that significant improvement is obtained when the upper integration limit is set using a signal to noise ratio criterion and that the spatial structure of dissipation rates is reproduced with this parameterization.

Sensitivity of CONUS Summer Rainfall to the Selection of Cumulus Parameterization Schemes in NU-WRF Seasonal Simulations

NASA Technical Reports Server (NTRS)

Iguchi, Takamichi; Tao, Wei-Kuo; Wu, Di; Peters-Lidard, Christa; Santanello, Joseph A.; Kemp, Eric; Tian, Yudong; Case, Jonathan; Wang, Weile; Ferraro, Robert;

When every drop counts: Analysis of Droughts in Brazil for the 1901-2013 period.

PubMed

Awange, Joseph L; Mpelasoka, Freddie; Goncalves, Rodrigo M

2016-10-01

To provide information useful in policy formulation and management of drought impacts in Brazil, in this study, a sequence of drought events based on monthly rainfall of 1901-2013 on ~25 km x 25 km grid are derived at 4 timescales that include short-timescales (3-month and 6-month) and medium to long-timescales (12-month and 24-month). Subsequently, probability of drought occurrences, intensity, duration and areal-extent are calculated. The probabilities of occurrence of severe and extreme droughts at short-timescales are 1 in 12 and 1 in 66 years, respectively, all over the country. At medium to long-timescales, the probability of severe droughts is about 1 in 20 years in northern Brazil, and 1 in 10 years in the south. The probabilities of extreme droughts are 1 in 9 and 1 in 12 years over northern Brazil and in the south, respectively. In general, no evidence of significant (α =0.05) trend is detected in drought frequency, intensity, and duration over the last 11 decades (since 1901) at all the 4 timescales. The drought areal-extent show increasing trends of 3.4%/decade over Brazil for both 3-month and 6-month timescales. However, the trend increases for the 12-month and 24-month timescales are relatively smaller, i.e., 2.4%/decade and 0.5%/decade, respectively. Copyright © 2016 Elsevier B.V. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sun, Yu-Han; Wang, Jun-Xian; Chen, Xiao-Yang

Quasars are variable on timescales from days to years in UV/optical and generally appear bluer while they brighten. The physics behind the variations in fluxes and colors remains unclear. Using Sloan Digital Sky Survey g- and r-band photometric monitoring data for quasars in Stripe 82, we find that although the flux variation amplitude increases with timescale, the color variability exhibits the opposite behavior. The color variability of quasars is prominent at timescales as short as ∼10 days, but gradually reduces toward timescales up to years. In other words, the variable emission at shorter timescales is bluer than that at longermore » timescales. This timescale dependence is clearly and consistently detected at all redshifts from z = 0 to 3.5; thus, it cannot be due to contamination to broadband photometry from emission lines that do not respond to fast continuum variations. The discovery directly rules out the possibility that simply attributes the color variability to contamination from a non-variable redder component such as the host galaxy. It cannot be interpreted as changes in global accretion rate either. The thermal accretion disk fluctuation model is favored in the sense that fluctuations in the inner, hotter region of the disk are responsible for short-term variations, while longer-term and stronger variations are expected from the larger and cooler disk region. An interesting implication is that one can use quasar variations at different timescales to probe disk emission at different radii.« less

Spatial Covariability of Temperature and Hydroclimate as a Function of Timescale During the Common Era

NASA Astrophysics Data System (ADS)

McKay, N.

2017-12-01

As timescale increases from years to centuries, the spatial scale of covariability in the climate system is hypothesized to increase as well. Covarying spatial scales are larger for temperature than for hydroclimate, however, both aspects of the climate system show systematic changes on large-spatial scales on orbital to tectonic timescales. The extent to which this phenomenon is evident in temperature and hydroclimate at centennial timescales is largely unknown. Recent syntheses of multidecadal to century-scale variability in hydroclimate during the past 2k in the Arctic, North America, and Australasia show little spatial covariability in hydroclimate during the Common Era. To determine 1) the evidence for systematic relationships between the spatial scale of climate covariability as a function of timescale, and 2) whether century-scale hydroclimate variability deviates from the relationship between spatial covariability and timescale, we quantify this phenomenon during the Common Era by calculating the e-folding distance in large instrumental and paleoclimate datasets. We calculate this metric of spatial covariability, at different timescales (1, 10 and 100-yr), for a large network of temperature and precipitation observations from the Global Historical Climatology Network (n=2447), from v2.0.0 of the PAGES2k temperature database (n=692), and from moisture-sensitive paleoclimate records North America, the Arctic, and the Iso2k project (n = 328). Initial results support the hypothesis that the spatial scale of covariability is larger for temperature, than for precipitation or paleoclimate hydroclimate indicators. Spatially, e-folding distances for temperature are largest at low latitudes and over the ocean. Both instrumental and proxy temperature data show clear evidence for increasing spatial extent as a function of timescale, but this phenomenon is very weak in the hydroclimate data analyzed here. In the proxy hydroclimate data, which are predominantly indicators of effective moisture, e-folding distance increases from annual to decadal timescales, but does not continue to increase to centennial timescales. Future work includes examining additional instrumental and proxy datasets of moisture variability, and extending the analysis to millennial timescales of variability.

Combinatorial Broadening Mechanism of O-H Stretching Bands in H-Bonded Molecular Clusters

NASA Astrophysics Data System (ADS)

Pitsevich, G. A.; Doroshenko, I. Yu.; Pogorelov, V. E.; Pettersson, L. G. M.; Sablinskas, V.; Sapeshko, V. V.; Balevicius, V.

2016-07-01

A new mechanism for combinatorial broadening of donor-OH stretching-vibration absorption bands in molecular clusters with H-bonds is proposed. It enables the experimentally observed increase of the O-H stretching-vibration bandwidth with increasing number of molecules in H-bonded clusters to be explained. Knowledge of the half-width of the OH stretching-vibration absorption band in the dimer and the number of H-bonds in the analyzed cluster is suffi cient in the zeroth-order approximation to estimate the O-H stretching-absorption bands in clusters containing several molecules. Good agreement between the calculated and published experimental half-widths of the OH stretching-vibration absorption bands in MeOH and PrOH clusters was obtained using this approach.

A cephalometric study of velar stretch in adolescent subjects.

PubMed

Simpson, R K; Colton, J

1980-01-01

Cephalometric x-rays were used to evaluate velar stretch in 20 normal adolescents during the production of /s/. Radiopaque markers were used so that the behaviors of both the anterior and posterior portions and the total velum cound be evaluated. Velar stretch was found in each of the subjects with the average stretch (15.19%) greater than the amount reported for 10-year-old subjects but less than the average stretch for adults. The correlation between amount of velar stretch and need ratio was not significant. The different stages of involution of adenoid tissue, which is characteristic of this age group, resulted in varying configurations of the naso-pharynx were postulated as one possible explanation for this unexpected finding. Normative data and clinical implications are presented.

A BARYONIC EFFECT ON THE MERGER TIMESCALE OF GALAXY CLUSTERS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Congyao; Yu, Qingjuan; Lu, Youjun, E-mail: yuqj@pku.edu.cn

2016-04-01

Accurate estimation of the merger timescales of galaxy clusters is important for understanding the cluster merger process and further understanding the formation and evolution of the large-scale structure of the universe. In this paper, we explore a baryonic effect on the merger timescale of galaxy clusters by using hydrodynamical simulations. We find that the baryons play an important role in accelerating the merger process. The merger timescale decreases upon increasing the gas fraction of galaxy clusters. For example, the merger timescale is shortened by a factor of up to 3 for merging clusters with gas fractions of 0.15, compared withmore » the timescale obtained with 0 gas fractions. The baryonic effect is significant for a wide range of merger parameters and is particularly more significant for nearly head-on mergers and high merging velocities. The baryonic effect on the merger timescale of galaxy clusters is expected to have an impact on the structure formation in the universe, such as the cluster mass function and massive substructures in galaxy clusters, and a bias of “no-gas” may exist in the results obtained from the dark matter-only cosmological simulations.« less

The Grell-Freitas Convection Parameterization: Recent Developments and Applications Within the NASA GEOS Global Model

NASA Technical Reports Server (NTRS)

Freitas, Saulo R.; Grell, Georg; Molod, Andrea; Thompson, Matthew A.

2017-01-01

We implemented and began to evaluate an alternative convection parameterization for the NASA Goddard Earth Observing System (GEOS) global model. The parameterization is based on the mass flux approach with several closures, for equilibrium and non-equilibrium convection, and includes scale and aerosol awareness functionalities. Recently, the scheme has been extended to a tri-modal spectral size approach to simulate the transition from shallow, mid, and deep convection regimes. In addition, the inclusion of a new closure for non-equilibrium convection resulted in a substantial gain of realism in model simulation of the diurnal cycle of convection over the land. Here, we briefly introduce the recent developments, implementation, and preliminary results of this parameterization in the NASA GEOS modeling system.

Parameterized LMI Based Diagonal Dominance Compensator Study for Polynomial Linear Parameter Varying System

NASA Astrophysics Data System (ADS)

Han, Xiaobao; Li, Huacong; Jia, Qiusheng

2017-12-01

For dynamic decoupling of polynomial linear parameter varying(PLPV) system, a robust dominance pre-compensator design method is given. The parameterized precompensator design problem is converted into an optimal problem constrained with parameterized linear matrix inequalities(PLMI) by using the conception of parameterized Lyapunov function(PLF). To solve the PLMI constrained optimal problem, the precompensator design problem is reduced into a normal convex optimization problem with normal linear matrix inequalities (LMI) constraints on a new constructed convex polyhedron. Moreover, a parameter scheduling pre-compensator is achieved, which satisfies robust performance and decoupling performances. Finally, the feasibility and validity of the robust diagonal dominance pre-compensator design method are verified by the numerical simulation on a turbofan engine PLPV model.

Evolution of Timescales from Astronomy to Physical Metrology

DTIC Science & Technology

2011-07-20

2000 [7] recommended the use of the ‘non-rotating origin’ both in the Geocentric Celestial Reference System (GCRS) and the International Terrestrial...timescale defined in a geocentric reference frame with the SI second as realized on the rotating geoid as the scale unit’ [30, 31]. This meant that it was...of the new timescale for apparent geocentric ephemerides, will be 1977 January 1d.0003725 (1d 00h 00m 32.184s) exactly. (b) The unit of this timescale

Can chronic stretching change the muscle-tendon mechanical properties? A review.

PubMed

Freitas, S R; Mendes, B; Le Sant, G; Andrade, R J; Nordez, A; Milanovic, Z

2018-03-01

It is recognized that stretching is an effective method to chronically increase the joint range of motion. However, the effects of stretching training on the muscle-tendon structural properties remain unclear. This systematic review with meta-analysis aimed to determine whether chronic stretching alter the muscle-tendon structural properties. Published papers regarding longitudinal stretching (static, dynamic and/or PNF) intervention (either randomized or not) in humans of any age and health status, with more than 2 weeks in duration and at least 2 sessions per week, were searched in PubMed, PEDro, ScienceDirect and ResearchGate databases. Structural or mechanical variables from joint (maximal tolerated passive torque or resistance to stretch) or muscle-tendon unit (muscle architecture, stiffness, extensibility, shear modulus, volume, thickness, cross-sectional area, and slack length) were extracted from those papers. A total of 26 studies were selected, with a duration ranging from 3 to 8 weeks, and an average total time under stretching of 1165 seconds per week. Small effects were seen for maximal tolerated passive torque, but trivial effects were seen for joint resistance to stretch, muscle architecture, muscle stiffness, and tendon stiffness. A large heterogeneity was seen for most of the variables. Stretching interventions with 3- to 8-week duration do not seem to change either the muscle or the tendon properties, although it increases the extensibility and tolerance to a greater tensile force. Adaptations to chronic stretching protocols shorter than 8 weeks seem to mostly occur at a sensory level. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Periostin inhibits mechanical stretch-induced apoptosis in osteoblast-like MG-63 cells.

PubMed

Yu, Kai-Wen; Yao, Chung-Chen; Jeng, Jiiang-Huei; Shieh, Hao-Ying; Chen, Yi-Jane

2018-04-01

Appropriate mechanical stress plays an important role in regulating the proliferation and differentiation of osteoblasts, whereas high-level mechanical stress may be harmful and compromise cell survival. Periostin, a matricellular protein, is essential in maintaining functional integrity of bone and collagen-rich connective tissue in response to mechanical stress. This study investigated whether or not high-level mechanical stretch induces cell apoptosis and the regulatory role of periostin in mechanical stretch-induced apoptosis in osteoblastic cells. Osteoblast-like MG-63 cells were seeded onto Bio-Flex I culture plates and subjected to cyclic mechanical stretching (15% elongation, 0.1 Hz) in a Flexercell tension plus system-5000. The same process was applied to cells pre-treated with exogenous human recombinant periostin before mechanical stretching. We used a chromatin condensation and membrane permeability dead cell apoptosis kit to evaluate the stretch-induced cell responses. Expression of caspase-3 and cPARP was examined by immunofluorescent stain and flow cytometry. The expression of periostin in MG-63 cells is involved in the TGF-β signaling pathway. High-level cyclic mechanical stretch induced apoptotic responses in MG-63 osteoblastic cells. The percentages of apoptotic cells and cells expressing cPARP protein increased in the groups of cells subjected to mechanical stretch, but these responses were absent in the presence of exogenous periostin. Our study revealed that high-level mechanical stretch induces apoptotic cell death, and that periostin plays a protective role against mechanical stretch-induced apoptosis in osteoblastic cells. Copyright © 2017. Published by Elsevier B.V.

Statistics of Advective Stretching in Three-dimensional Incompressible Flows

NASA Astrophysics Data System (ADS)

Subramanian, Natarajan; Kellogg, Louise H.; Turcotte, Donald L.

2009-09-01

We present a method to quantify kinematic stretching in incompressible, unsteady, isoviscous, three-dimensional flows. We extend the method of Kellogg and Turcotte (J. Geophys. Res. 95:421-432, 1990) to compute the axial stretching/thinning experienced by infinitesimal ellipsoidal strain markers in arbitrary three-dimensional incompressible flows and discuss the differences between our method and the computation of Finite Time Lyapunov Exponent (FTLE). We use the cellular flow model developed in Solomon and Mezic (Nature 425:376-380, 2003) to study the statistics of stretching in a three-dimensional unsteady cellular flow. We find that the probability density function of the logarithm of normalised cumulative stretching (log S) for a globally chaotic flow, with spatially heterogeneous stretching behavior, is not Gaussian and that the coefficient of variation of the Gaussian distribution does not decrease with time as t^{-1/2} . However, it is observed that stretching becomes exponential log S˜ t and the probability density function of log S becomes Gaussian when the time dependence of the flow and its three-dimensionality are increased to make the stretching behaviour of the flow more spatially uniform. We term these behaviors weak and strong chaotic mixing respectively. We find that for strongly chaotic mixing, the coefficient of variation of the Gaussian distribution decreases with time as t^{-1/2} . This behavior is consistent with a random multiplicative stretching process.

Passive versus active stretching of hip flexor muscles in subjects with limited hip extension: a randomized clinical trial.

PubMed

Winters, Michael V; Blake, Charles G; Trost, Jennifer S; Marcello-Brinker, Toni B; Lowe, Lynne M; Garber, Matthew B; Wainner, Robert S

2004-09-01

Active stretching is purported to stretch the shortened muscle and simultaneously strengthen the antagonist muscle. The purpose of this study was to determine whether active and passive stretching results in a difference between groups at improving hip extension range of motion in patients with hip flexor muscle tightness. Thirty-three patients with low back pain and lower-extremity injuries who showed decreased range of motion, presumably due to hip flexor muscle tightness, completed the study. The subjects, who had a mean age of 23.6 years (SD = 5.3, range = 18-25), were randomly assigned to either an active home stretching group or a passive home stretching group. Hip extension range of motion was measured with the subjects in the modified Thomas test position at baseline and 3 and 6 weeks after the start of the study. Range of motion in both groups improved over time, but there were no differences between groups. The results indicate that passive and active stretching are equally effective for increasing range of motion, presumably due to increased flexibility of tight hip flexor muscles. Whether the 2 methods equally improve flexibility of other muscle groups or whether active stretching improves the function of the antagonist muscles is not known. Active and passive stretching both appeared to increase the flexibility of tight hip flexor muscles in patients with musculoskeletal impairments.

Comparison of 2 Dosages of Stretching Treatment in Infants with Congenital Muscular Torticollis: A Randomized Trial.

PubMed

He, Lu; Yan, Xiaohua; Li, Jinling; Guan, Buyun; Ma, Liying; Chen, Ying; Mai, Jianning; Xu, Kaishou

2017-05-01

To compare the short-term efficacy of 2 dosages of stretching treatment on the clinical outcomes in infants with congenital muscular torticollis. This was a prospective randomized controlled study. Fifty infants with congenital muscular torticollis who were randomly assigned to 100-times stretching group and 50-times stretching group received stretching treatment for the affected sternocleidomastoid muscle. The outcomes including the head tilt, the cervical passive range of motion, and the muscle function of cervical lateral flexors determined by the muscle function scale were assessed at baseline and at 4 and 8 weeks after treatment. The sternocleidomastoid muscle growth analyzed by the thickness ratio of sternocleidomastoid muscles was measured using ultrasonography at baseline and 8 weeks after treatment. Except the ratio of muscle function scale scores, the postintervention outcomes were all significantly improved in both groups compared with baseline (P < 0.05). The 100-times stretching group showed greater improvement compared with 50-times stretching group in head tilt and cervical passive range of motion at 4 and 8 weeks after treatment (P < 0.05). Stretching treatment of 2 dosages may effectively improve head tilt, cervical passive range of motion, and sternocleidomastoid muscle growth in infants with congenital muscular torticollis. The stretching treatment of 100 times per day is likely to associate with greater improvement in head tilt and cervical passive range of motion.

Adenosine monophosphate-activated protein kinase activation and suppression of inflammatory response by cell stretching in rabbit synovial fibroblasts.

PubMed

Kunanusornchai, Wanlop; Muanprasat, Chatchai; Chatsudthipong, Varanuj

2016-12-01

Joint mobilization is known to be beneficial in osteoarthritis (OA) patients. This study aimed to investigate the effect of stretching on adenosine monophosphate-activated protein kinase (AMPK) activity and its role in modulating inflammation in rabbit synovial fibroblasts. Uniaxial stretching of isolated rabbit synovial fibroblasts for ten min was performed. Stretching-induced AMPK activation, its underlying mechanism, and its anti-inflammatory effect were investigated using Western blot. Static stretching at 20 % of initial length resulted in AMPK activation characterized by expression of phosphorylated AMPK and phosphorylated acetyl-Co A carboxylase. AMP-activated protein kinase phosphorylation peaked 1 h after stretching and declined toward resting activity. Using cell viability assays, static stretching did not appear to cause cellular damage. Activation of AMPK involves Ca 2+ influx via a mechanosensitive L-type Ca 2+ channel, which subsequently raises intracellular Ca 2+ and activates AMPK via Ca 2+ /calmodulin-dependent protein kinase kinase β (CaMKKβ). Interestingly, stretching suppressed TNFα-induced expression of COX-2, iNOS, and phosphorylated NF-κB. These effects were prevented by pretreatment with compound C, an AMPK inhibitor. These results suggest that mechanical stretching suppressed inflammatory responses in synovial fibroblasts via a L-type Ca 2+ -channel-CaMKKβ-AMPK-dependent pathway which may underlie joint mobilization's ability to alleviate OA symptoms.

Torsion-inversion tunneling patterns in the CH-stretch vibrationally excited states of the G12 family of molecules including methylamine.

PubMed

Dawadi, Mahesh B; Bhatta, Ram S; Perry, David S

2013-12-19

Two torsion-inversion tunneling models (models I and II) are reported for the CH-stretch vibrationally excited states in the G12 family of molecules. The torsion and inversion tunneling parameters, h(2v) and h(3v), respectively, are combined with low-order coupling terms involving the CH-stretch vibrations. Model I is a group theoretical treatment starting from the symmetric rotor methyl CH-stretch vibrations; model II is an internal coordinate model including the local-local CH-stretch coupling. Each model yields predicted torsion-inversion tunneling patterns of the four symmetry species, A, B, E1, and E2, in the CH-stretch excited states. Although the predicted tunneling patterns for the symmetric CH-stretch excited state are the same as for the ground state, inverted tunneling patterns are predicted for the asymmetric CH-stretches. The qualitative tunneling patterns predicted are independent of the model type and of the particular coupling terms considered. In model I, the magnitudes of the tunneling splittings in the two asymmetric CH-stretch excited states are equal to half of that in the ground state, but in model II, they differ when the tunneling rate is fast. The model predictions are compared across the series of molecules methanol, methylamine, 2-methylmalonaldehyde, and 5-methyltropolone and to the available experimental data.

Orientation and length of mammalian skeletal myocytes in response to a unidirectional stretch

NASA Technical Reports Server (NTRS)

Collinsworth, A. M.; Torgan, C. E.; Nagda, S. N.; Rajalingam, R. J.; Kraus, W. E.; Truskey, G. A.

2000-01-01

Effects of mechanical forces exerted on mammalian skeletal muscle cells during development were studied using an in vitro model to unidirectionally stretch cultured C2C12 cells grown on silastic membrane. Previous models to date have not studied these responses of the mammalian system specifically. The silastic membrane upon which these cells were grown exhibited linear strain behavior over the range of 3.6-14.6% strain, with a Poisson's ratio of approximately 0.5. To mimic murine in utero long bone growth, cell substrates were stretched at an average strain rate of 2.36%/day for 4 days or 1.77%/day for 6 days with an overall membrane strain of 9.5% and 10.6%, respectively. Both control and stretched fibers stained positively for the contractile protein, alpha-actinin, demonstrating muscle fiber development. An effect of stretch on orientation and length of myofibers was observed. At both strain rates, stretched fibers aligned at a smaller angle relative to the direction of stretch and were significantly longer compared to randomly oriented control fibers. There was no effect of duration of stretch on orientation or length, suggesting the cellular responses are independent of strain rate for the range tested. These results demonstrate that, under conditions simulating mammalian long bone growth, cultured myocytes respond to mechanical forces by lengthening and orienting along the direction of stretch.

Discovery of a Similar to 5 Day Characteristic Timescale in the Kepler Power Spectrum of Zw 229-15

NASA Technical Reports Server (NTRS)

Edelson, R.; Vaughan, S.; Malkan, M.; Kelly, B. C.; Smith, K. L.; Boyd, P. T.; Mushotzky, R.

2014-01-01

We present time series analyses of the full Kepler dataset of Zw 229- 15. This Kepler light curve- with a baseline greater than three years, composed of virtually continuous, evenly sampled 30-minute measurements - is unprecedented in its quality and precision. We utilize two methods of power spectral analysis to investigate the optical variability and search for evidence of a bend frequency associated with a characteristic optical variability timescale. Each method yields similar results. The first interpolates across data gaps to use the standard Fourier periodogram. The second, using the CARMA-based time-domain modeling technique of Kelly et al., does not need evenly-sampled data. Both methods find excess power at high frequencies that may be due to Kepler instrumental effects. More importantly both also show strong bends (delta alpha is approx. 2) at timescales of approx. 5 days, a feature similar to those seen in the X-ray PSDs of AGN but never before in the optical. This observed approx. 5 day timescale may be associated with one of several physical processes potentially responsible for the variability. A plausible association could be made with light -crossing, dynamical or thermal timescales, depending on the assumed value of the accretion disk size and on unobserved disk parameters such as alpha and H¬R. This timescale is not consistent with the viscous timescale, which would be years in a approx. 10(exp7) solar mass AGN such as Zw 229- 15. However there must be a second bend on long (& 1 year) timescales, and that feature could be associated with the viscous timescale.

77 FR 21805 - Notice of Intent To Collect Fees on Public Land in Mesa County, CO (Ruby-Horsethief Stretch of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-11

... Intent To Collect Fees on Public Land in Mesa County, CO (Ruby-Horsethief Stretch of the Colorado River... fees for overnight camping on the Ruby-Horsethief stretch of the Colorado River, between Loma, Colorado, and the Colorado State Line, Mesa County, Colorado. The Ruby-Horsethief stretch of the Colorado River...

Role of Ca2+ signaling in initiation of stretch-induced apoptosis in neonatal heart cells.

PubMed

Liao, Xu Dong; Tang, Ai Hui; Chen, Quan; Jin, Hai Jing; Wu, Cai Hong; Chen, Lan-Ying; Wang, Shi Qiang

2003-10-17

Abnormal mechanical load, as seen in hypertension, is found to induce heart cell apoptosis, yet the signaling link between cell stretch and apoptotic pathways is not known. Using an in vitro stretch model mimicking diastolic pressure stress, here we show that Ca(2+) signaling participates essentially in the early stage of stretch-induced apoptosis. In neonatal rat cardiomyocytes, the moderate 20% stretch resulted in tonic elevation of intracellular free Ca(2+) ([Ca(2+)](i)). Buffering [Ca(2+)](i) by EGTA-AM, suppressing ryanodine-sensitive Ca(2+) release, and blocking L-type Ca(2+) channels all prevented the stretch-induced apoptosis as assessed by phosphatidylserine exposure and nuclear fragmentation. Notably, Ca(2+) suppression also prevented known stretch-activated apoptotic events, including caspase-3/-9 activation, mitochondrial membrane potential corruption, and reactive oxygen species production, suggesting that Ca(2+) signaling is the upstream of these events. Since [Ca(2+)](i) did not change without activating mechanosensitive Ca(2+) entry, we conclude that stretch-induced Ca(2+) entry, via the Ca(2+)-induced Ca(2+) release mechanism, plays an important role in initiating apoptotic signaling during mechanical stress.

Fast-crawling cell types migrate to avoid the direction of periodic substratum stretching

PubMed Central

Okimura, Chika; Ueda, Kazuki; Sakumura, Yuichi; Iwadate, Yoshiaki

2016-01-01

ABSTRACT To investigate the relationship between mechanical stimuli from substrata and related cell functions, one of the most useful techniques is the application of mechanical stimuli via periodic stretching of elastic substrata. In response to this stimulus, Dictyostelium discoideum cells migrate in a direction perpendicular to the stretching direction. The origins of directional migration, higher migration velocity in the direction perpendicular to the stretching direction or the higher probability of a switch of migration direction to perpendicular to the stretching direction, however, remain unknown. In this study, we applied periodic stretching stimuli to neutrophil-like differentiated HL-60 cells, which migrate perpendicular to the direction of stretch. Detailed analysis of the trajectories of HL-60 cells and Dictyostelium cells obtained in a previous study revealed that the higher probability of a switch of migration direction to that perpendicular to the direction of stretching was the main cause of such directional migration. This directional migration appears to be a strategy adopted by fast-crawling cells in which they do not migrate faster in the direction they want to go, but migrate to avoid a direction they do not want to go. PMID:26980079

Effects of Plantar Flexor Muscle Static Stretching Alone and Combined With Massage on Postural Balance.

PubMed

Hemmati, Ladan; Rojhani-Shirazi, Zahra; Ebrahimi, Samaneh

2016-10-01

To evaluate and compare the effects of stretching and combined therapy (stretching and massage) on postural balance in people aged 50 to 65 years. Twenty-three subjects participated in this nonrandomized clinical trial study. Each participant randomly received plantar flexor muscle stretching (3 cycles of 45 seconds with a 30-second recovery period between cycles) alone and in combination with deep stroking massage (an interval of at least 30 minutes separated the two interventions). The data were recorded with a force platform immediately after each condition with eyes open and closed. The center of pressure displacement and velocity along the mediolateral and anteroposterior axes were calculated under each condition. The data were analyzed with multiple-pair t-tests. The center of pressure displacement and velocity along the mediolateral axis increased after both stretching and the combined intervention. There were significant differences in both values between participants in the stretching and combined interventions (p<0.05). Plantar flexor muscle stretching (for 45 seconds) combined with deep stroking massage may have more detrimental effects on postural balance than stretching alone because each intervention can intensify the effects of the other.

Adaptation of rat soleus muscles to 4 wk of intermittent strain

NASA Technical Reports Server (NTRS)

Stauber, W. T.; Miller, G. R.; Grimmett, J. G.; Knack, K. K.

1994-01-01

The effect of repeated strains on rat soleus muscles was investigated by stretching active muscles 3 times/wk for 4 wk with two different methods of stretching. The adaptation of myofibers and noncontractile tissue was followed by histochemical techniques and computer-assisted image analysis. Muscle hypertrophy was seen in the slow-stretched muscles, which increased in mass by 13% and increased in myofiber cross-sectional area by 30%. In the fast-stretched muscle, mass increased by 10% but myofiber cross-sectional area actually decreased. This decrease in mean fiber area was the result of a population of very small fibers (population A) that coexisted with slightly smaller normal-sized fibers (population B). Fibers in population A did not have the distribution expected from atrophy compared with atrophic fibers from unloaded muscles; they were much smaller. In addition, there was a 44% increase in noncontractile tissue in the fast-stretched muscles. Thus, soleus muscles subjected to repeated strains respond differently to slow and fast stretching. Slow stretching results in typical muscle hypertrophy, whereas fast stretching produces somewhat larger muscles but with a mixture of small and normal-sized myofibers accompanied by a marked proliferation of noncontractile tissue.

Factors That Influence the Efficacy of Stretching Programs for Patients With Hypomobility

PubMed Central

Jacobs, Cale A.; Sciascia, Aaron D.

2011-01-01

Context: Passive stretching exercise protocols, as part of outpatient treatment or home exercise programs, are used to improve hypomobility. Despite the cosmopolitan use of stretching exercises, little is known about the forces being applied to the joint during these routine treatments. Type of Study: Clinical review. Evidence Acquisition: Articles were identified using MEDLINE and Google Scholar databases, with searches initially limited to those articles published after 1995. Seminal articles that were referenced were also included. Results: Many factors contribute to the clinical success of a stretching program, including the frequency, intensity, and duration of the stretching exercises, as well as patient- and joint-specific factors. Conclusions: The goal of a stretching protocol is to maximize total end-range time both in the clinic and at home. Higher intensity, prolonged, and frequent stretching (10- to 15-minute bouts, 3 to 6 times per day) used as an adjunct to high-grade mobilizations may be beneficial for certain hypomobility conditions. PMID:23016052

Muscle progenitor cells proliferation doesn't sufficiently contribute to maintaining stretched soleus muscle mass during gravitational unloading

NASA Astrophysics Data System (ADS)

Tarakina, M. V.; Turtikova, O. V.; Nemirovskaya, T. L.; Kokontcev, A. A.; Shenkman, B. S.

Skeletal muscle work hypertrophy is usually connected with muscle progenitor satellite cells (SC) activation with subsequent incorporation of their nuclei into myofibers. Passive stretch of unloaded muscle was earlier established to prevent atrophic processes and is accompanied by enhanced protein synthesis. We hypothesized that elimination of SC proliferation capacity by γ-irradiation would partly avert stretched muscle fiber capability to maintain their size under the conditions of gravitational unloading. To assess the role of muscle progenitor (satellite) cells in development of passive stretch preventive effect SC proliferation was suppressed by local exposing to ionized radiation (2500 rad), subsequent hindlimb suspension or hindlimb suspension with concomitant passive stretch were carried out. Reduction of myofiber cross-sectional area and decrease in myonuclei number accompanying unloaded muscle atrophy were completely abolished by passive stretch both in irradiated and sham-treated animals. We conclude that SC did not make essential contribution to passive stretch preventive action under the conditions of simulated weightlessness.

Intraplaque stretch in carotid atherosclerotic plaque--an effective biomechanical predictor for subsequent cerebrovascular ischemic events.

PubMed

Teng, Zhongzhao; Sadat, Umar; Wang, Wenkai; Bahaei, Nasim S; Chen, Shengyong; Young, Victoria E; Graves, Martin J; Gillard, Jonathan H

2013-01-01

Stretch is a mechanical parameter, which has been proposed previously to affect the biological activities in different tissues. This study explored its utility in determining plaque vulnerability. One hundred and six patients with mild to moderate carotid stenosis were recruited in this study (53 symptomatic and 53 asymptomatic). High resolution, multi-sequence magnetic resonance (MR) imaging was performed to delineate various plaque components. Finite element method was used to predict high stretch concentration within the plaque. During a two-year follow-up, 11 patients in symptomatic group and 3 in asymptomatic group experienced recurrent cerebrovascular events. Plaque stretch at systole and stretch variation during one cardiac cycle was greater in symptomatic group than those in the asymptomatic. Within the symptomatic group, a similar trend was observed in patients with recurrent events compared to those without. Plaques with high stretch concentration and large stretch variation are associated with increased risk of future cerebrovascular events.

Modeling particle nucleation and growth over northern California during the 2010 CARES campaign

NASA Astrophysics Data System (ADS)

Lupascu, A.; Easter, R.; Zaveri, R.; Shrivastava, M.; Pekour, M.; Tomlinson, J.; Yang, Q.; Matsui, H.; Hodzic, A.; Zhang, Q.; Fast, J. D.

2015-11-01

Accurate representation of the aerosol lifecycle requires adequate modeling of the particle number concentration and size distribution in addition to their mass, which is often the focus of aerosol modeling studies. This paper compares particle number concentrations and size distributions as predicted by three empirical nucleation parameterizations in the Weather Research and Forecast coupled with chemistry (WRF-Chem) regional model using 20 discrete size bins ranging from 1 nm to 10 μm. Two of the parameterizations are based on H2SO4, while one is based on both H2SO4 and organic vapors. Budget diagnostic terms for transport, dry deposition, emissions, condensational growth, nucleation, and coagulation of aerosol particles have been added to the model and are used to analyze the differences in how the new particle formation parameterizations influence the evolving aerosol size distribution. The simulations are evaluated using measurements collected at surface sites and from a research aircraft during the Carbonaceous Aerosol and Radiative Effects Study (CARES) conducted in the vicinity of Sacramento, California. While all three parameterizations captured the temporal variation of the size distribution during observed nucleation events as well as the spatial variability in aerosol number, all overestimated by up to a factor of 2.5 the total particle number concentration for particle diameters greater than 10 nm. Using the budget diagnostic terms, we demonstrate that the combined H2SO4 and low-volatility organic vapor parameterization leads to a different diurnal variability of new particle formation and growth to larger sizes compared to the parameterizations based on only H2SO4. At the CARES urban ground site, peak nucleation rates are predicted to occur around 12:00 Pacific (local) standard time (PST) for the H2SO4 parameterizations, whereas the highest rates were predicted at 08:00 and 16:00 PST when low-volatility organic gases are included in the parameterization. This can be explained by higher anthropogenic emissions of organic vapors at these times as well as lower boundary-layer heights that reduce vertical mixing. The higher nucleation rates in the H2SO4-organic parameterization at these times were largely offset by losses due to coagulation. Despite the different budget terms for ultrafine particles, the 10-40 nm diameter particle number concentrations from all three parameterizations increased from 10:00 to 14:00 PST and then decreased later in the afternoon, consistent with changes in the observed size and number distribution. We found that newly formed particles could explain up to 20-30 % of predicted cloud condensation nuclei at 0.5 % supersaturation, depending on location and the specific nucleation parameterization. A sensitivity simulation using 12 discrete size bins ranging from 1 nm to 10 μm diameter gave a reasonable estimate of particle number and size distribution compared to the 20 size bin simulation, while reducing the associated computational cost by ~ 36 %.

Application of new parameterizations of gas transfer velocity and their impact on regional and global marine CO 2 budgets

NASA Astrophysics Data System (ADS)

Fangohr, Susanne; Woolf, David K.

2007-06-01

One of the dominant sources of uncertainty in the calculation of air-sea flux of carbon dioxide on a global scale originates from the various parameterizations of the gas transfer velocity, k, that are in use. Whilst it is undisputed that most of these parameterizations have shortcomings and neglect processes which influence air-sea gas exchange and do not scale with wind speed alone, there is no general agreement about their relative accuracy. The most widely used parameterizations are based on non-linear functions of wind speed and, to a lesser extent, on sea surface temperature and salinity. Processes such as surface film damping and whitecapping are known to have an effect on air-sea exchange. More recently published parameterizations use friction velocity, sea surface roughness, and significant wave height. These new parameters can account to some extent for processes such as film damping and whitecapping and could potentially explain the spread of wind-speed based transfer velocities published in the literature. We combine some of the principles of two recently published k parameterizations [Glover, D.M., Frew, N.M., McCue, S.J. and Bock, E.J., 2002. A multiyear time series of global gas transfer velocity from the TOPEX dual frequency, normalized radar backscatter algorithm. In: Donelan, M.A., Drennan, W.M., Saltzman, E.S., and Wanninkhof, R. (Eds.), Gas Transfer at Water Surfaces, Geophys. Monograph 127. AGU,Washington, DC, 325-331; Woolf, D.K., 2005. Parameterization of gas transfer velocities and sea-state dependent wave breaking. Tellus, 57B: 87-94] to calculate k as the sum of a linear function of total mean square slope of the sea surface and a wave breaking parameter. This separates contributions from direct and bubble-mediated gas transfer as suggested by Woolf [Woolf, D.K., 2005. Parameterization of gas transfer velocities and sea-state dependent wave breaking. Tellus, 57B: 87-94] and allows us to quantify contributions from these two processes independently. We then apply our parameterization to a monthly TOPEX altimeter gridded 1.5° × 1.5° data set and compare our results to transfer velocities calculated using the popular wind-based k parameterizations by Wanninkhof [Wanninkhof, R., 1992. Relationship between wind speed and gas exchange over the ocean. J. Geophys. Res., 97: 7373-7382.] and Wanninkhof and McGillis [Wanninkhof, R. and McGillis, W., 1999. A cubic relationship between air-sea CO2 exchange and wind speed. Geophys. Res. Lett., 26(13): 1889-1892]. We show that despite good agreement of the globally averaged transfer velocities, global and regional fluxes differ by up to 100%. These discrepancies are a result of different spatio-temporal distributions of the processes involved in the parameterizations of k, indicating the importance of wave field parameters and a need for further validation.

Evolution of foot-and-mouth disease virus serotype A capsid coding (P1) region on a timescale of three decades in an endemic context.

PubMed

Das, Biswajit; Mohapatra, Jajati K; Pande, Veena; Subramaniam, Saravanan; Sanyal, Aniket

2016-07-01

Three decades-long (1977-2013) evolutionary trend of the capsid coding (P1) region of foot-and-mouth disease virus (FMDV) serotype A isolated in India was analysed. The exclusive presence of genotype 18 since 2001 and the dominance of the VP3(59)-deletion group of genotype 18 was evident in the recent years. Clade 18c was found to be currently the only active one among the three clades (18a, 18b and 18c) identified in the deletion group. The rate of evolution of the Indian isolates at the capsid region was found to be 4.96×10(-3)substitutions/site/year. The timescale analysis predicted the most recent common ancestor to have existed during 1962 for Indian FMDV serotype A and around 1998 for the deletion group. The evolutionary pattern of serotype A in India appears to be homogeneous as no spatial or temporal structure was observed. Bayesian skyline plots indicate a sharp decline in the effective number of infections after 2008, which might be a result of mass vaccination or inherent loss of virus fitness. Analyses of variability at 38 known antigenically critical positions in a countrywide longitudinal data set suggested that the substitutions neither followed any specific trend nor remained fixed for a long period since frequent reversions and convergence was noticed. A maximum of 6 different amino acid residues was seen in the gene pool at any antigenically critical site over the decades, suggesting a limited combination of residues being responsible for the observed antigenic variation. Evidence of positive selection at some of the antigenically critical residues and the structurally proximal positions suggest a possible role of pre-existing immunity in the host population in driving evolution. The VP1 C-terminus neither revealed variability nor positive selection, suggesting the possibility that this stretch does not contribute to the antigenic variation and adaptation under immune selection. Copyright © 2016 Elsevier B.V. All rights reserved.

On one-dimensional stretching functions for finite-difference calculations. [computational fluid dynamics

NASA Technical Reports Server (NTRS)

Vinokur, M.

1979-01-01

The class of one-dimensional stretching functions used in finite-difference calculations is studied. For solutions containing a highly localized region of rapid variation, simple criteria for a stretching function are derived using a truncation error analysis. These criteria are used to investigate two types of stretching functions. One is an interior stretching function, for which the location and slope of an interior clustering region are specified. The simplest such function satisfying the criteria is found to be one based on the inverse hyperbolic sine. The other type of function is a two-sided stretching function, for which the arbitrary slopes at the two ends of the one-dimensional interval are specified. The simplest such general function is found to be one based on the inverse tangent.

Bruxism: Is There an Indication for Muscle-Stretching Exercises?

PubMed

Gouw, Simone; de Wijer, Anton; Creugers, Nico Hj; Kalaykova, Stanimira I

Bruxism is a common phenomenon involving repetitive activation of the masticatory muscles. Muscle-stretching exercises are a recommended part of several international guidelines for musculoskeletal disorders and may be effective in management of the jaw muscle activity that gives rise to bruxism. However, most studies of muscle-stretching exercises have mainly focused on their influence on performance (eg, range of motion, coordination, and muscle strength) of the limb or trunk muscles of healthy individuals or individuals with sports-related injuries. Very few have investigated stretching of the human masticatory muscles and none muscle-stretching exercises in the management of (sleep) bruxism. This article reviews the literature on muscle-stretching exercises and their potential role in the management of sleep bruxism or its consequences in the musculoskeletal system.

Enhancement of multispectral thermal infrared images - Decorrelation contrast stretching

NASA Technical Reports Server (NTRS)

Gillespie, Alan R.

1992-01-01

Decorrelation contrast stretching is an effective method for displaying information from multispectral thermal infrared (TIR) images. The technique involves transformation of the data to principle components ('decorrelation'), independent contrast 'stretching' of data from the new 'decorrelated' image bands, and retransformation of the stretched data back to the approximate original axes, based on the inverse of the principle component rotation. The enhancement is robust in that colors of the same scene components are similar in enhanced images of similar scenes, or the same scene imaged at different times. Decorrelation contrast stretching is reviewed in the context of other enhancements applied to TIR images.

Engelmann Spruce Site Index Models: A Comparison of Model Functions and Parameterizations

PubMed Central

Nigh, Gordon

2015-01-01

Engelmann spruce (Picea engelmannii Parry ex Engelm.) is a high-elevation species found in western Canada and western USA. As this species becomes increasingly targeted for harvesting, better height growth information is required for good management of this species. This project was initiated to fill this need. The objective of the project was threefold: develop a site index model for Engelmann spruce; compare the fits and modelling and application issues between three model formulations and four parameterizations; and more closely examine the grounded-Generalized Algebraic Difference Approach (g-GADA) model parameterization. The model fitting data consisted of 84 stem analyzed Engelmann spruce site trees sampled across the Engelmann Spruce – Subalpine Fir biogeoclimatic zone. The fitted models were based on the Chapman-Richards function, a modified Hossfeld IV function, and the Schumacher function. The model parameterizations that were tested are indicator variables, mixed-effects, GADA, and g-GADA. Model evaluation was based on the finite-sample corrected version of Akaike’s Information Criteria and the estimated variance. Model parameterization had more of an influence on the fit than did model formulation, with the indicator variable method providing the best fit, followed by the mixed-effects modelling (9% increase in the variance for the Chapman-Richards and Schumacher formulations over the indicator variable parameterization), g-GADA (optimal approach) (335% increase in the variance), and the GADA/g-GADA (with the GADA parameterization) (346% increase in the variance). Factors related to the application of the model must be considered when selecting the model for use as the best fitting methods have the most barriers in their application in terms of data and software requirements. PMID:25853472

Constraints to Dark Energy Using PADE Parameterizations

NASA Astrophysics Data System (ADS)

Rezaei, M.; Malekjani, M.; Basilakos, S.; Mehrabi, A.; Mota, D. F.

2017-07-01

We put constraints on dark energy (DE) properties using PADE parameterization, and compare it to the same constraints using Chevalier-Polarski-Linder (CPL) and ΛCDM, at both the background and the perturbation levels. The DE equation of the state parameter of the models is derived following the mathematical treatment of PADE expansion. Unlike CPL parameterization, PADE approximation provides different forms of the equation of state parameter that avoid the divergence in the far future. Initially we perform a likelihood analysis in order to put constraints on the model parameters using solely background expansion data, and we find that all parameterizations are consistent with each other. Then, combining the expansion and the growth rate data, we test the viability of PADE parameterizations and compare them with CPL and ΛCDM models, respectively. Specifically, we find that the growth rate of the current PADE parameterizations is lower than ΛCDM model at low redshifts, while the differences among the models are negligible at high redshifts. In this context, we provide for the first time a growth index of linear matter perturbations in PADE cosmologies. Considering that DE is homogeneous, we recover the well-known asymptotic value of the growth index (namely {γ }∞ =\\tfrac{3({w}∞ -1)}{6{w}∞ -5}), while in the case of clustered DE, we obtain {γ }∞ ≃ \\tfrac{3{w}∞ (3{w}∞ -5)}{(6{w}∞ -5)(3{w}∞ -1)}. Finally, we generalize the growth index analysis in the case where γ is allowed to vary with redshift, and we find that the form of γ (z) in PADE parameterization extends that of the CPL and ΛCDM cosmologies, respectively.

Electronegativity equalization method: parameterization and validation for organic molecules using the Merz-Kollman-Singh charge distribution scheme.

PubMed

Jirousková, Zuzana; Vareková, Radka Svobodová; Vanek, Jakub; Koca, Jaroslav

2009-05-01

The electronegativity equalization method (EEM) was developed by Mortier et al. as a semiempirical method based on the density-functional theory. After parameterization, in which EEM parameters A(i), B(i), and adjusting factor kappa are obtained, this approach can be used for calculation of average electronegativity and charge distribution in a molecule. The aim of this work is to perform the EEM parameterization using the Merz-Kollman-Singh (MK) charge distribution scheme obtained from B3LYP/6-31G* and HF/6-31G* calculations. To achieve this goal, we selected a set of 380 organic molecules from the Cambridge Structural Database (CSD) and used the methodology, which was recently successfully applied to EEM parameterization to calculate the HF/STO-3G Mulliken charges on large sets of molecules. In the case of B3LYP/6-31G* MK charges, we have improved the EEM parameters for already parameterized elements, specifically C, H, N, O, and F. Moreover, EEM parameters for S, Br, Cl, and Zn, which have not as yet been parameterized for this level of theory and basis set, we also developed. In the case of HF/6-31G* MK charges, we have developed the EEM parameters for C, H, N, O, S, Br, Cl, F, and Zn that have not been parameterized for this level of theory and basis set so far. The obtained EEM parameters were verified by a previously developed validation procedure and used for the charge calculation on a different set of 116 organic molecules from the CSD. The calculated EEM charges are in a very good agreement with the quantum mechanically obtained ab initio charges. 2008 Wiley Periodicals, Inc.

Disturbance to wintering western snowy plovers

USGS Publications Warehouse

Lafferty, Kevin D.

2001-01-01

In order to better understand the nature of disturbances to wintering snowy plovers, I observed snowy plovers and activities that might disturb them at a beach near Devereux Slough in Santa Barbara, California, USA. Disturbance (activity that caused plovers to move or fly) to wintering populations of threatened western snowy plovers was 16 times higher at a public beach than at protected beaches. Wintering plovers reacted to disturbance at half the distance (∼40 m) as has been reported for breeding snowy plovers (∼80 m). Humans, dogs, crows and other birds were the main sources of disturbance on the public beach, and each snowy plover was disturbed, on average, once every 27 weekend min and once every 43 weekday min. Dogs off leash were a disproportionate source of disturbance. Plovers were more likely to fly from dogs, horses and crows than from humans and other shorebirds. Plovers were less abundant near trail heads. Over short time scales, plovers did not acclimate to or successfully find refuge from disturbance. Feeding rates declined with increased human activity. I used data from these observations to parameterize a model that predicted rates of disturbance given various management actions. The model found that prohibiting dogs and a 30 m buffer zone surrounding a 400 m stretch of beach provided the most protection for plovers for the least amount of impact to beach recreation.

Comments on “A Unified Representation of Deep Moist Convection in Numerical Modeling of the Atmosphere. Part I”

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Guang; Fan, Jiwen; Xu, Kuan-Man

2015-06-01

Arakawa and Wu (2013, hereafter referred to as AW13) recently developed a formal approach to a unified parameterization of atmospheric convection for high-resolution numerical models. The work is based on ideas formulated by Arakawa et al. (2011). It lays the foundation for a new parameterization pathway in the era of high-resolution numerical modeling of the atmosphere. The key parameter in this approach is convective cloud fraction. In conventional parameterization, it is assumed that <<1. This assumption is no longer valid when horizontal resolution of numerical models approaches a few to a few tens kilometers, since in such situations convective cloudmore » fraction can be comparable to unity. Therefore, they argue that the conventional approach to parameterizing convective transport must include a factor 1 - in order to unify the parameterization for the full range of model resolutions so that it is scale-aware and valid for large convective cloud fractions. While AW13’s approach provides important guidance for future convective parameterization development, in this note we intend to show that the conventional approach already has this scale awareness factor 1 - built in, although not recognized for the last forty years. Therefore, it should work well even in situations of large convective cloud fractions in high-resolution numerical models.« less

Cloud Simulations in Response to Turbulence Parameterizations in the GISS Model E GCM

NASA Technical Reports Server (NTRS)

Yao, Mao-Sung; Cheng, Ye

2013-01-01

The response of cloud simulations to turbulence parameterizations is studied systematically using the GISS general circulation model (GCM) E2 employed in the Intergovernmental Panel on Climate Change's (IPCC) Fifth Assessment Report (AR5).Without the turbulence parameterization, the relative humidity (RH) and the low cloud cover peak unrealistically close to the surface; with the dry convection or with only the local turbulence parameterization, these two quantities improve their vertical structures, but the vertical transport of water vapor is still weak in the planetary boundary layers (PBLs); with both local and nonlocal turbulence parameterizations, the RH and low cloud cover have better vertical structures in all latitudes due to more significant vertical transport of water vapor in the PBL. The study also compares the cloud and radiation climatologies obtained from an experiment using a newer version of turbulence parameterization being developed at GISS with those obtained from the AR5 version. This newer scheme differs from the AR5 version in computing nonlocal transports, turbulent length scale, and PBL height and shows significant improvements in cloud and radiation simulations, especially over the subtropical eastern oceans and the southern oceans. The diagnosed PBL heights appear to correlate well with the low cloud distribution over oceans. This suggests that a cloud-producing scheme needs to be constructed in a framework that also takes the turbulence into consideration.

Stretch Marks

MedlinePlus

... stretch marks. This isn't true with regular tanning or tanning beds , though: Stretch marks are less likely to ... up looking more obvious. Plus, the sun and tanning beds do more harm than good when it ...

Modelling heterogeneous ice nucleation on mineral dust and soot with parameterizations based on laboratory experiments

NASA Astrophysics Data System (ADS)

Hoose, C.; Hande, L. B.; Mohler, O.; Niemand, M.; Paukert, M.; Reichardt, I.; Ullrich, R.

2016-12-01

Between 0 and -37°C, ice formation in clouds is triggered by aerosol particles acting as heterogeneous ice nuclei. At lower temperatures, heterogeneous ice nucleation on aerosols can occur at lower supersaturations than homogeneous freezing of solutes. In laboratory experiments, the ability of different aerosol species (e.g. desert dusts, soot, biological particles) has been studied in detail and quantified via various theoretical or empirical parameterization approaches. For experiments in the AIDA cloud chamber, we have quantified the ice nucleation efficiency via a temperature- and supersaturation dependent ice nucleation active site density. Here we present a new empirical parameterization scheme for immersion and deposition ice nucleation on desert dust and soot based on these experimental data. The application of this parameterization to the simulation of cirrus clouds, deep convective clouds and orographic clouds will be shown, including the extension of the scheme to the treatment of freezing of rain drops. The results are compared to other heterogeneous ice nucleation schemes. Furthermore, an aerosol-dependent parameterization of contact ice nucleation is presented.

Evaluation of Aerosol-cloud Interaction in the GISS Model E Using ARM Observations

NASA Technical Reports Server (NTRS)

DeBoer, G.; Bauer, S. E.; Toto, T.; Menon, Surabi; Vogelmann, A. M.

2013-01-01

Observations from the US Department of Energy's Atmospheric Radiation Measurement (ARM) program are used to evaluate the ability of the NASA GISS ModelE global climate model in reproducing observed interactions between aerosols and clouds. Included in the evaluation are comparisons of basic meteorology and aerosol properties, droplet activation, effective radius parameterizations, and surface-based evaluations of aerosol-cloud interactions (ACI). Differences between the simulated and observed ACI are generally large, but these differences may result partially from vertical distribution of aerosol in the model, rather than the representation of physical processes governing the interactions between aerosols and clouds. Compared to the current observations, the ModelE often features elevated droplet concentrations for a given aerosol concentration, indicating that the activation parameterizations used may be too aggressive. Additionally, parameterizations for effective radius commonly used in models were tested using ARM observations, and there was no clear superior parameterization for the cases reviewed here. This lack of consensus is demonstrated to result in potentially large, statistically significant differences to surface radiative budgets, should one parameterization be chosen over another.

Multi-Scale Modeling and the Eddy-Diffusivity/Mass-Flux (EDMF) Parameterization

NASA Astrophysics Data System (ADS)

Teixeira, J.

2015-12-01

Turbulence and convection play a fundamental role in many key weather and climate science topics. Unfortunately, current atmospheric models cannot explicitly resolve most turbulent and convective flow. Because of this fact, turbulence and convection in the atmosphere has to be parameterized - i.e. equations describing the dynamical evolution of the statistical properties of turbulence and convection motions have to be devised. Recently a variety of different models have been developed that attempt at simulating the atmosphere using variable resolution. A key problem however is that parameterizations are in general not explicitly aware of the resolution - the scale awareness problem. In this context, we will present and discuss a specific approach, the Eddy-Diffusivity/Mass-Flux (EDMF) parameterization, that not only is in itself a multi-scale parameterization but it is also particularly well suited to deal with the scale-awareness problems that plague current variable-resolution models. It does so by representing small-scale turbulence using a classic Eddy-Diffusivity (ED) method, and the larger-scale (boundary layer and tropospheric-scale) eddies as a variety of plumes using the Mass-Flux (MF) concept.

A Testbed for Model Development

NASA Astrophysics Data System (ADS)

Berry, J. A.; Van der Tol, C.; Kornfeld, A.

2014-12-01

Carbon cycle and land-surface models used in global simulations need to be computationally efficient and have a high standard of software engineering. These models also make a number of scaling assumptions to simplify the representation of complex biochemical and structural properties of ecosystems. This makes it difficult to use these models to test new ideas for parameterizations or to evaluate scaling assumptions. The stripped down nature of these models also makes it difficult to "connect" with current disciplinary research which tends to be focused on much more nuanced topics than can be included in the models. In our opinion/experience this indicates the need for another type of model that can more faithfully represent the complexity ecosystems and which has the flexibility to change or interchange parameterizations and to run optimization codes for calibration. We have used the SCOPE (Soil Canopy Observation, Photochemistry and Energy fluxes) model in this way to develop, calibrate, and test parameterizations for solar induced chlorophyll fluorescence, OCS exchange and stomatal parameterizations at the canopy scale. Examples of the data sets and procedures used to develop and test new parameterizations are presented.

Effects of Combining Running and Practical Duration Stretching on Proprioceptive Skills of National Sprinters.

PubMed

Romero-Franco, Natalia; Párraga-Montilla, Juan Antonio; Molina-Flores, Enrique M; Jiménez-Reyes, Pedro

2018-06-01

Romero-Franco, N, Párraga-Montilla, JA, Molina-Flores, EM, and Jiménez-Reyes, P. Effects of combining running and practical duration stretching on proprioceptive skills of national sprinters. J Strength Cond Res XX(X): 000-000, 2018-Practical duration stretching after aerobic activities is a recommended component of the first part of warm-up because of its effects on performance. However, its effects on proprioceptive skills are unknown. This study aimed to analyze the effects of running and practical duration static stretching (SS) and dynamic stretching (DS) on postural balance and the joint position sense (JPS) of national sprinters. Thirty-two national sprinters were randomly classified into a SS group (n = 11), DS group (n = 11), or control group (n = 10). Static stretching performed 5 minutes of running and short-duration (20 seconds) static stretches; DS performed 5 minutes of running and short-duration dynamic (20 seconds) stretches; and the control group performed 5 minutes of running. Before and after the intervention, unipedal static postural balance and knee JPS were evaluated. Static stretching exhibited a more centralized center of pressure in the medial-lateral plane for unipedal static postural balance in right-leg support after stretching (p = 0.005, d = 1.24), whereas DS showed values further from the center after stretching for the same unipedal support compared with baseline (p = 0.042, d = 0.49), and the control group remained stable (p > 0.05). Joint position sense did not show significant differences in any group (p > 0.05). In conclusion, combining running and practical duration SS may be beneficial for right-leg postural stabilization, whereas DS may be partly and slightly deleterious. Both SS and DS combined with running and running alone have neutral effects on knee JPS. Sports professionals should consider running and practical duration SS as part of the warm-up of sprinters to partly improve unipedal static postural balance.

The Effectiveness of Neck Stretching Exercises Following Total Thyroidectomy on Reducing Neck Pain and Disability: A Randomized Controlled Trial.

PubMed

Ayhan, Hatice; Tastan, Sevinc; Iyigün, Emine; Oztürk, Erkan; Yildiz, Ramazan; Görgülü, Semih

2016-06-01

Although there are a limited number of studies showing effects of neck stretching exercises following a thyroidectomy in reducing neck discomfort symptoms, no study has specifically dealt with and examined the effect of neck stretching exercises on neck pain and disability. To analyze the effect of neck stretching exercises, following a total thyroidectomy, on reducing neck pain and disability. A randomized controlled trial was conducted. The participants were randomly assigned either to the stretching exercise group (n = 40) or to the control group (n = 40). The stretching exercise group learned the neck stretching exercises immediately after total thyroidectomy. The effects of the stretching exercises on the participants' neck pain and disability, neck sensitivity, pain with neck movements as well as on wound healing, were evaluated at the end of the first week and at 1 month following surgery. When comparing neck pain and disability scale (NPDS) scores, neck sensitivity and pain with neck movement before thyroidectomy, after 1 week and after 1-month time-points, it was found that patients experienced significantly less pain and disability in the stretching exercise group than the control group (p < .001). At the end of the first week, the NPDS scores (mean [SD] = 8.82 [12.23] vs. 30.28 [12.09]), neck sensitivity scores (median [IR] = 0 [.75] vs. 2.00 [4.0]) and pain levels with neck movements (median [IR] = 0 [2.0] vs. 3.5 [5.75]) of the stretching exercise group were significantly lower than those of the control group. However, there was no significant difference between the groups with regard to the scores at the 1-month evaluation (p > .05). Neck stretching exercises done immediately after a total thyroidectomy reduce short-term neck pain and disability symptoms. © 2016 Sigma Theta Tau International.

Effectiveness of Manual Therapy and Stretching for Baseball Players With Shoulder Range of Motion Deficits.

PubMed

Bailey, Lane B; Thigpen, Charles A; Hawkins, Richard J; Beattie, Paul F; Shanley, Ellen

Baseball players displaying deficits in shoulder range of motion (ROM) are at increased risk of arm injury. Currently, there is a lack of consensus regarding the best available treatment options to restore shoulder ROM. Instrumented manual therapy with self-stretching will result in clinically significant deficit reductions when compared with self-stretching alone. Controlled laboratory study. Shoulder ROM and humeral torsion were assessed in 60 active baseball players (mean age, 19 ± 2 years) with ROM deficits (nondominant - dominant, ≥15°). Athletes were randomly assigned to receive a single treatment of instrumented manual therapy plus self-stretching (n = 30) or self-stretching only (n = 30). Deficits in internal rotation, horizontal adduction, and total arc of motion were compared between groups immediately before and after a single treatment session. Treatment effectiveness was determined by mean comparison data, and a number-needed-to-treat (NNT) analysis was used for assessing the presence of ROM risk factors. Prior to intervention, players displayed significant ( P < 0.001) dominant-sided deficits in internal rotation (-26°), total arc of motion (-18°), and horizontal adduction (-17°). After the intervention, both groups displayed significant improvements in ROM, with the instrumented manual therapy plus self-stretching group displaying greater increases in internal rotation (+5°, P = 0.010), total arc of motion (+6°, P = 0.010), and horizontal adduction (+7°, P = 0.004) compared with self-stretching alone. For horizontal adduction deficits, the added use of instrumented manual therapy with self-stretching decreased the NNT to 2.2 (95% CI, 2.1-2.4; P = 0.010). Instrumented manual therapy with self-stretching significantly reduces ROM risk factors in baseball players with motion deficits when compared with stretching alone. The added benefits of manual therapy may help to reduce ROM deficits in clinical scenarios where stretching alone is ineffective.

Combining Dynamic Stretch and Tunable Stiffness to Probe Cell Mechanobiology In Vitro

PubMed Central

Throm Quinlan, Angela M.; Sierad, Leslie N.; Capulli, Andrew K.; Firstenberg, Laura E.; Billiar, Kristen L.

2011-01-01

Cells have the ability to actively sense their mechanical environment and respond to both substrate stiffness and stretch by altering their adhesion, proliferation, locomotion, morphology, and synthetic profile. In order to elucidate the interrelated effects of different mechanical stimuli on cell phenotype in vitro, we have developed a method for culturing mammalian cells in a two-dimensional environment at a wide range of combined levels of substrate stiffness and dynamic stretch. Polyacrylamide gels were covalently bonded to flexible silicone culture plates and coated with monomeric collagen for cell adhesion. Substrate stiffness was adjusted from relatively soft (G′ = 0.3 kPa) to stiff (G′ = 50 kPa) by altering the ratio of acrylamide to bis-acrylamide, and the silicone membranes were stretched over circular loading posts by applying vacuum pressure to impart near-uniform stretch, as confirmed by strain field analysis. As a demonstration of the system, porcine aortic valve interstitial cells (VIC) and human mesenchymal stem cells (hMSC) were plated on soft and stiff substrates either statically cultured or exposed to 10% equibiaxial or pure uniaxial stretch at 1Hz for 6 hours. In all cases, cell attachment and cell viability were high. On soft substrates, VICs cultured statically exhibit a small rounded morphology, significantly smaller than on stiff substrates (p<0.05). Following equibiaxial cyclic stretch, VICs spread to the extent of cells cultured on stiff substrates, but did not reorient in response to uniaxial stretch to the extent of cells stretched on stiff substrates. hMSCs exhibited a less pronounced response than VICs, likely due to a lower stiffness threshold for spreading on static gels. These preliminary data demonstrate that inhibition of spreading due to a lack of matrix stiffness surrounding a cell may be overcome by externally applied stretch suggesting similar mechanotransduction mechanisms for sensing stiffness and stretch. PMID:21858051

Influence of different shortening velocities preceding stretch on human triceps surae moment generation in vivo.

PubMed

De Monte, Gianpiero; Arampatzis, Adamantios

2008-07-19

The purpose of this study was to examine the influence of different shortening velocities preceding the stretch on moment generation of the triceps surae muscles and architecture of the m. gastrocnemius medialis after shortening-stretch cycles of equal magnitude in vivo. Eleven male subjects (31.6+/-5.8 years, 178.4+/-7.3cm, 80.6+/-9.6kg) performed a series of electro-stimulated (85Hz) shortening-stretch plantar flexion contractions. The shortening-stretch cycles were performed at three constant angular velocities (25, 50, 100 degrees /s) in the plantar flexion direction (shortening) and at 50 degrees /s in the dorsiflexion direction (stretching). The resultant ankle joint moments were calculated through inverse dynamics. Pennation angle and fascicle length of the m. gastrocnemius medialis at rest and during contractions were measured using ultrasonography. The corresponding ankle moments, kinematics and changes in muscle architecture were analysed at seven time intervals. An analysis of variance for repeated measurements and post hoc test with Bonferroni correction was used to check the velocity-related effects on moment enhancement (alpha=0.05). The results show an increase in pennation angles and a decrease in fascicle lengths after the shortening-stretch cycle. The ankle joint moment ratio (post to pre) was higher (p<0.01) than 1.0 indicating a moment enhancement after the shortening-stretch cycle. The found ankle joint moment enhancement was 2-5% after the shortening-stretch cycle and was independed of the shortening velocity. Furthermore, the decrease in fascicle length after the shortening-stretch cycle indicates that the moment enhancement found in the present study is underestimated at least by 1-3%. Considering that the experiments have been done at the ascending limb of the force-length curve and that force enhancement is higher at the descending and the plateau region of the force-length curve, we conclude that the moment enhancement after shortening-stretch cycle can have important physiological affects while locomotion.

Healthy Lifestyle: Women's Health

MedlinePlus

... increase the resistance level as you get stronger. Stretching. Stretching can help improve flexibility. Set aside time to ... when your muscles are warm and receptive to stretching. Stability and balance. Balance exercises improve stability and ...

Single molecule studies of flexible polymers under shear and mixed flows

NASA Astrophysics Data System (ADS)

Teixeira, Rodrigo Esquivel

We combine manipulation and single molecule visualization of flexible DNA polymers with the generation of controlled simple shear and planar mixed flows for the investigation of polymer flow physics. With the ability to observe polymer conformation directly and follow its evolution in both dilute and entangled regimes we provide a direct test for molecular models. The coil-stretch transition of polymer extension was investigated in planar mixed flows approaching simple shear. Visualization of individual molecules revealed a sharp coil-stretch transition in the steady-state length of the polymer with increasing strain rate in flows slightly more straining than rotational. In slightly more rotational flows significant transient polymer deformation was observed. Next, dilute polymers were visualized in the flow-gradient plane of a steady shear flow. By exploiting the linear proportionality between polymer mass and image intensity, the radius of gyration tensor elements ( Gij) were measured over time. Then, the Giesekus stress tensor was used to obtain the bulk shear viscosity and first normal stress coefficient, thus performing rheology measurements from single molecule conformations. End-over-end tumbling was discovered for the first time, confirming a long-standing prediction and numerous single-chain computer simulation studies. The tumbling frequency followed Wi0.62, and an equation derived from simple advection and diffusion arguments was able to reproduce these observations. Power spectral densities of chain orientation trajectories were found to be single-peaked around the tumbling frequency, thus suggesting a periodic character for polymer dynamics. Finally, we investigated well-entangled polymer solutions. Identical preparations were used in both rheological characterizations and single molecule observations under a variety of shear flow histories. Polymer extension relaxations after the cessation of a fast shear flow revealed two intrinsic characteristic times. The fast one was insensitive to concentration and at least an order of magnitude larger than the Rouse time presupposed by theoretical treatments. The slow timescale grew steeply with concentration, in qualitative agreement with theory. Transient and steady shear flows showed vastly different conformations even among identical molecules subjected to identical flow histories. This "molecular individualism" of well-entangled solutions and its broad conformational distributions calls into question the validity of preaveraging approximations made in molecular-level theories.

Tide-related seismic velocity changes across the English Channel

NASA Astrophysics Data System (ADS)

de Ridder, S.; Valova, V.; Curtis, A.

2016-12-01

Temporal changes in the seismic velocities in the Earth's subsurface are known to occur due to a range of phenomena including seasonal variations, magmatic activity, nonlinear healing after strong ground motion, and glacial loading and unloading. Our goal is to extend observations of small velocity changes towards shorter timescales. Earth tides caused by the gravitational attraction between the Earth and the Moon might affect seismic properties. If tidal velocity variations can be recovered from long range cross-correlations, and can also be coupled to stress-strain induced variations in the elastic properties, that would pave the way for systematic imaging of rheological properties of the upper crust. With this long-term goal, we studied data recorded between January 2010 and December 2015 by four broad-band instruments from the British Geological Survey network. One station is located in Cornwall, two in Devon, and one across the English Channel on the island of Jersey. Continuous seismic recordings of the vertical components of particle velocity were divided into one hour intervals, bandpass filtered between 0.02 and 0.11 Hz, spectrally whitened, and cross-correlated between station pairs. The resulting cross-correlations were stacked into bins corresponding to the average water levels observed at nearby ports resulting in cross-correlation traces as a function of water level, for each station pair. To detect temporal changes, a multi-window time-shift analysis is applied to these inter-station traces. We find a stretch factor that best translates one trace into another: this stretch is indicative of changes in average seismic velocities between the pair of tidal phases. We detected systematic seismic velocity variations as a function of water level. We find that increasing water level coincided with decreasing seismic velocities. Separating the data according to up- and down-going tidal tracts reveals that the observed velocity changes exhibit a time-lag, assuming that tide-induced strain is the dominant controlling factor. We discuss potential mechanisms for the observed seismic velocity dependency on water level including the effect of a thicker water layer on the dispersion characteristics of seismic velocities, and tidal loading related changes in the elastic properties of the subsurface.

Nitric oxide regulates stretch-induced proliferation in C2C12 myoblasts.

PubMed

Soltow, Quinlyn A; Lira, Vitor A; Betters, Jenna L; Long, Jodi H D; Sellman, Jeff E; Zeanah, Elizabeth H; Criswell, David S

2010-09-01

Mechanical stretch of skeletal muscle activates nitric oxide (NO) production and is an important stimulator of satellite cell proliferation. Further, cyclooxygenase (COX) activity has been shown to promote satellite cell proliferation in response to stretch. Since COX-2 expression in skeletal muscle can be regulated by NO we sought to determine if NO is required for stretch-induced myoblast proliferation and whether supplemental NO can counter the effects of COX-2 and NF-kappaB inhibitors. C2C12 myoblasts were cultured for 24 h, then switched to medium containing either the NOS inhibitor, L-NAME (200 microM), the COX-2 specific inhibitor NS-398 (100 microM), the NF-kappaB inhibiting antioxidant, PDTC (5 mM), the nitric oxide donor, DETA-NONOate (10-100 microM) or no supplement (control) for 24 h. Subgroups of each treatment were exposed to 1 h of 15% cyclic stretch (1 Hz), and were then allowed to proliferate for 24 h before fixing. Proliferation was measured by BrdU incorporation during the last hour before fixing, and DAPI stain. Stretch induced a twofold increase in nuclear number compared to control, and this effect was completely inhibited by L-NAME, NS-398 or PDTC (P < 0.05). Although DETA-NONOate (10 microM) did not affect basal proliferation, the NO-donor augmented the stretch-induced increase in proliferation and rescued stretch-induced proliferation in NS-398-treated cells, but not in PDTC-treated cells. In conclusion, NO, COX-2, and NF-kappaB are necessary for stretch-induced proliferation of myoblasts. Although COX-2 and NF-kappaB are both involved in basal proliferation, NO does not affect basal growth. Thus, NO requires the synergistic effect of stretch in order to induce muscle cell proliferation.

The acute effects of stretching with vibration on dynamic flexibility in young female gymnasts.

PubMed

Johnson, Aaron W; Warcup, Caisa N; Seeley, Matthew K; Eggett, Dennis; Feland, Jeffery B

2018-01-10

While stretching with vibration has been shown to improve static flexibility; the effect of stretching with vibration on dynamic flexibility is not well known. The purpose of this study was to examine the effectiveness of stretching with vibration on acute dynamic flexibility and jump height in novice and advanced competitive female gymnasts during a split jump. Female gymnast (n=27, age: 11.5 ± 1.7 years, Junior Olympic levels 5-10) participated in this cross-over study. Dynamic flexibility during gymnastic split jumps were video recorded and analyzed with Dartfish software. All participants completed both randomized stretching protocols with either the vibration platform turned on (VIB) (frequency of 30 Hz and 2 mm amplitude) or off (NoVIB) separated by 48 h. Participants performed 4 sets of three stretches on the vibration platform. Each stretch was held for 30 s with 5 s rest for a total of 7 min of stretch. Split jump flexibility decreased significantly from pre to post measurement in both VIB (-5.8°±5.9°) (p<0.001) and NoVIB (-2.6°±6.1°) (p=0.041) conditions (adjusted for gymnast level). This effect was greatest in lower skill level gymnasts (p=0.003), while the highest skill level gymnasts showed no significant decrease in the split jump (p=0.105). Jump height was not significantly different between conditions (p=0.892) or within groups (p=0.880). An acute session of static stretching with or without vibration immediately before performance does not alter jump height. Stretching with vibration immediately prior to gymnastics competition decreases split jump flexibility in lower level gymnasts more than upper level gymnasts.

Simulated physiological stretch increases expression of extracellular matrix proteins in human bladder smooth muscle cells via integrin α4/αv-FAK-ERK1/2 signaling pathway.

PubMed

Chen, Shulian; Peng, Chuandu; Wei, Xin; Luo, Deyi; Lin, Yifei; Yang, Tongxin; Jin, Xi; Gong, Lina; Li, Hong; Wang, Kunjie

2017-08-01

To investigate the effect of simulated physiological stretch on the expression of extracellular matrix (ECM) proteins and the role of integrin α4/αv, focal adhesion kinase (FAK), extracellular regulated protein kinases 1/2 (ERK1/2) in the stretch-induced ECM protein expression of human bladder smooth muscle cells (HBSMCs). HBSMCs were seeded onto silicone membrane and subjected to simulated physiological stretch at the range of 5, 10, and 15% elongation. Expression of primary ECM proteins in HBSMCs was analyzed by real-time polymerase chain reaction and Western blot. Specificity of the FAK and ERK1/2 was determined by Western blot with FAK inhibitor and ERK1/2 inhibitor (PD98059). Specificity of integrin α4 and integrin αv was determined with small interfering ribonucleic acid (siRNA) transfection. The expression of collagen I (Col1), collagen III (Col3), and fibronectin (Fn) was increased significantly under the simulated physiological stretch of 10 and 15%. Integrin α4 and αv, FAK, ERK1/2 were activated by 10% simulated physiological stretch compared with the static condition. Pretreatment of ERK1/2 inhibitor, FAK inhibitor, integrin α4 siRNA, or integrin αv siRNA reduced the stretch-induced expression of ECM proteins. And FAK inhibitor decreased the stretch-induced ERK1/2 activity and ECM protein expression. Integrin α4 siRNA or integrin αv siRNA inhibited the stretch-induced activity of FAK. Simulated physiological stretch increases the expression of ECM proteins in HBSMCs, and integrin α4/αv-FAK-ERK1/2 signaling pathway partly modulates the mechano-transducing process.

Cardiovascular Responses to Skeletal Muscle Stretching: "Stretching" the Truth or a New Exercise Paradigm for Cardiovascular Medicine?

PubMed

Kruse, Nicholas T; Scheuermann, Barry W

2017-12-01

Stretching is commonly prescribed with the intended purpose of increasing range of motion, enhancing muscular coordination, and preventing prolonged immobilization induced by aging or a sedentary lifestyle. Emerging evidence suggests that acute or long-term stretching exercise may modulate a variety of cardiovascular responses. Specifically, at the onset of stretch, the mechanical deformation of the vascular bed coupled with stimulation of group III muscle afferent fibers initiates a cascade of events resulting in both peripheral vasodilation and a heart rate-driven increase in cardiac output, blood pressure, and muscle blood flow. This potential to increase shear stress and blood flow without the use of excessive muscle energy expenditure may hold important implications for future therapeutic vascular medicine and cardiac health. However, the idea that a cardiovascular component may be involved in human skeletal muscle stretching is relatively new. Therefore, the primary intent of this review is to highlight topics related to skeletal muscle stretching and cardiovascular regulation and function. The current evidence suggests that acute stretching causes a significant macro- and microcirculatory event that alters blood flow and the relationship between oxygen availability and oxygen utilization. These acute vascular changes if performed chronically may result in improved endothelial function, improved arterial blood vessel stiffness, and/or reduced blood pressure. Although several mechanisms have been postulated, an increased nitric oxide bioavailability has been highlighted as one promising candidate for the improvement in vessel function with stretching. Collectively, the evidence provided in this review suggests that stretching acutely or long term may serve as a novel and alternative low intensity therapeutic intervention capable of improving several parameters of vascular function.

Stretched size of atrial septal defect predicted by intracardiac echocardiography.

PubMed

Lin, Ming-Chih; Fu, Yun-Ching; Jan, Sheng-Ling; Ho, Chi-Lin; Hwang, Betau

2010-01-01

The stretched size of an atrial septal defect (ASD) is important for device selection during transcatheter closure. However, balloon sizing carries potential risks such as hypotension, bradycardia, or laceration of the atrial septum. The aim of the present study was to investigate the accuracy of the predicted stretched size of ASD by intracardiac echocardiography (ICE). From December 2004 to November 2007, 136 consecutive patients with single secundum type ASD undergoing transcatheter closure of their defect using the Amplatzer septal occluder under ICE guidance were enrolled for analysis. There were 43 males and 93 females. The age ranged from 2.2 to 79.1 years with a median age of 13.4 years. The body weight ranged from 12.1 to 93.2 kg with a median body weight of 45.8 kg. The stretched size of ASD measured by a sizing plate was considered as the standard. ASD sizes measured by ICE in bicaval and short-axis views predicted the stretched size by formulae derived from linear regressions. The predicted stretched sizes obtained using 2 formulae, 1.34 x radicalbicaval xshort axis (formula 1) and 1.22 x larger diameter (formula 2), exhibited good agreement with the standard stretched size with Kappa values of 0.91 and 0.90, respectively. The accuracy rate of predicted stretched sizes within 2 mm, 3 mm, and 4 mm range of the standard size were 32.8%, 45.4%, and 57.7% (formula 1) and 33.1%, 50%, and 63.2% (formula 2). The stretched size of ASD predicted by ICE exhibited good agreement with the standard stretched size. This prediction provides helpful information, especially if balloon sizing cannot be adequately performed.

Mechanical stretch is a highly selective regulator of gene expression in human bladder smooth muscle cells.

PubMed

Adam, Rosalyn M; Eaton, Samuel H; Estrada, Carlos; Nimgaonkar, Ashish; Shih, Shu-Ching; Smith, Lois E H; Kohane, Isaac S; Bägli, Darius; Freeman, Michael R

2004-12-15

Application of mechanical stimuli has been shown to alter gene expression in bladder smooth muscle cells (SMC). To date, only a limited number of "stretch-responsive" genes in this cell type have been reported. We employed oligonucleotide arrays to identify stretch-sensitive genes in primary culture human bladder SMC subjected to repetitive mechanical stimulation for 4 h. Differential gene expression between stretched and nonstretched cells was assessed using Significance Analysis of Microarrays (SAM). Expression of 20 out of 11,731 expressed genes ( approximately 0.17%) was altered >2-fold following stretch, with 19 genes induced and one gene (FGF-9) repressed. Using real-time RT-PCR, we tested independently the responsiveness of 15 genes to stretch and to platelet-derived growth factor-BB (PDGF-BB), another hypertrophic stimulus for bladder SMC. In response to both stimuli, expression of 13 genes increased, 1 gene (FGF-9) decreased, and 1 gene was unchanged. Six transcripts (HB-EGF, BMP-2, COX-2, LIF, PAR-2, and FGF-9) were evaluated using an ex vivo rat model of bladder distension. HB-EGF, BMP-2, COX-2, LIF, and PAR-2 increased with bladder stretch ex vivo, whereas FGF-9 decreased, consistent with expression changes observed in vitro. In silico analysis of microarray data using the FIRED algorithm identified c-jun, AP-1, ATF-2, and neurofibromin-1 (NF-1) as potential transcriptional mediators of stretch signals. Furthermore, the promoters of 9 of 13 stretch-responsive genes contained AP-1 binding sites. These observations identify stretch as a highly selective regulator of gene expression in bladder SMC. Moreover, they suggest that mechanical and growth factor signals converge on common transcriptional regulators that include members of the AP-1 family.

Detrimental Effects of “Stretch” Goals in Specialty Substance Use Disorder Treatment Organizations

PubMed Central

Lemoine, G. James; Blum, Terry C.; Roman, Paul M.

2016-01-01

Background “Stretch” goals, a rarely examined concept that represents seemingly impossible, highly ambitious organizational goals ostensibly established to fill performance gaps and motivate employees, are examined within a sample of substance use disorder (SUD) treatment centers in the United States in terms of their prevalence and effects on organizational behavior. Stretch goals are defined as “seemingly impossible” goals intended to motivate employees to achieve high performance. In light of the high level of environmental change and unpredictability faced by SUD treatment centers in recent decades, we theorize that stretch goals would be both common and often detrimental (in terms of capacity utilization rate and efficiency) in these settings. Methods In a longitudinal analysis of data from leaders of a representative U. S. national sample of 219 SUD treatment centers characterized by entrepreneurial management structures, we examined the prevalence of stretch goals and their impact on key outcome variables of capacity utilization rate and efficiency. Results Widespread adoption of stretch goals was found, with 43% of our sample falling within the stretch category. Stretch goals had a negative main effect on capacity utilization rate as compared to less ambitious challenging goals. Stretch and prior performance interacted to further predict capacity utilization rate, whereas stretch and slack resource availability interacted to predict center efficiency. Discussion Although stretch goals are frequently used in the SUD treatment industry, we find them mostly detrimental to performance. Stretch goals may enhance the efficiency of treatment centers with prior limited resource availability, but they are negatively associated with capacity utilization, especially in centers with a record of already strong performance. Despite the high prevalence of such goals and positive values centered on aspirational behavior, these results strongly suggest caution in such goal setting in SUD treatment centers. PMID:26976811

Approaches for Subgrid Parameterization: Does Scaling Help?

NASA Astrophysics Data System (ADS)

Yano, Jun-Ichi

2016-04-01

Arguably the scaling behavior is a well-established fact in many geophysical systems. There are already many theoretical studies elucidating this issue. However, the scaling law is slow to be introduced in "operational" geophysical modelling, notably for weather forecast as well as climate projection models. The main purpose of this presentation is to ask why, and try to answer this question. As a reference point, the presentation reviews the three major approaches for traditional subgrid parameterization: moment, PDF (probability density function), and mode decomposition. The moment expansion is a standard method for describing the subgrid-scale turbulent flows both in the atmosphere and the oceans. The PDF approach is intuitively appealing as it directly deals with a distribution of variables in subgrid scale in a more direct manner. The third category, originally proposed by Aubry et al (1988) in context of the wall boundary-layer turbulence, is specifically designed to represent coherencies in compact manner by a low--dimensional dynamical system. Their original proposal adopts the proper orthogonal decomposition (POD, or empirical orthogonal functions, EOF) as their mode-decomposition basis. However, the methodology can easily be generalized into any decomposition basis. The mass-flux formulation that is currently adopted in majority of atmospheric models for parameterizing convection can also be considered a special case of the mode decomposition, adopting the segmentally-constant modes for the expansion basis. The mode decomposition can, furthermore, be re-interpreted as a type of Galarkin approach for numerically modelling the subgrid-scale processes. Simple extrapolation of this re-interpretation further suggests us that the subgrid parameterization problem may be re-interpreted as a type of mesh-refinement problem in numerical modelling. We furthermore see a link between the subgrid parameterization and downscaling problems along this line. The mode decomposition approach would also be the best framework for linking between the traditional parameterizations and the scaling perspectives. However, by seeing the link more clearly, we also see strength and weakness of introducing the scaling perspectives into parameterizations. Any diagnosis under a mode decomposition would immediately reveal a power-law nature of the spectrum. However, exploiting this knowledge in operational parameterization would be a different story. It is symbolic to realize that POD studies have been focusing on representing the largest-scale coherency within a grid box under a high truncation. This problem is already hard enough. Looking at differently, the scaling law is a very concise manner for characterizing many subgrid-scale variabilities in systems. We may even argue that the scaling law can provide almost complete subgrid-scale information in order to construct a parameterization, but with a major missing link: its amplitude must be specified by an additional condition. The condition called "closure" in the parameterization problem, and known to be a tough problem. We should also realize that the studies of the scaling behavior tend to be statistical in the sense that it hardly provides complete information for constructing a parameterization: can we specify the coefficients of all the decomposition modes by a scaling law perfectly when the first few leading modes are specified? Arguably, the renormalization group (RNG) is a very powerful tool for reducing a system with a scaling behavior into a low dimension, say, under an appropriate mode decomposition procedure. However, RNG is analytical tool: it is extremely hard to apply it to real complex geophysical systems. It appears that it is still a long way to go for us before we can begin to exploit the scaling law in order to construct operational subgrid parameterizations in effective manner.

[Current trends in the effects of stretching: application to physical exercise in the workplace].

PubMed

Eguchi, Yasumasa; Ohta, Masanori; Yamato, Hiroshi

2011-09-01

A review of the Survey on the State of Employees' Health by the Ministry of Health, Labour and Welfare (2008) shows that the most commonly implemented aspect as an activity of worksite health promotion is "Health counseling", and the second is "Workplace physical exercise." Physical exercise, "Taiso", is acceptable and sustainable for workers, as it is easy to do in a group or alone. Various modes of stretching are implemented for workplace physical exercise. However, articles suggesting negative or contradictory effects of stretching have increased in recent years. Several review articles have revealed that static stretching may induce impairments of muscle power performance and no stretching will prevent or reduce muscle soreness after exercise. There are various aims of workplace physical exercise, so we have to consider the situational method when we apply stretching to occupational health.

On One-Dimensional Stretching Functions for Finite-Difference Calculations

NASA Technical Reports Server (NTRS)

Vinokur, M.

1980-01-01

The class of one dimensional stretching function used in finite difference calculations is studied. For solutions containing a highly localized region of rapid variation, simple criteria for a stretching function are derived using a truncation error analysis. These criteria are used to investigate two types of stretching functions. One is an interior stretching function, for which the location and slope of an interior clustering region are specified. The simplest such function satisfying the criteria is found to be one based on the inverse hyperbolic sine. The other type of function is a two sided stretching function, for which the arbitrary slopes at the two ends of the one dimensional interval are specified. The simplest such general function is found to be one based on the inverse tangent. The general two sided function has many applications in the construction of finite difference grids.

On one-dimensional stretching functions for finite-difference calculations. [computational fluid dynamics

NASA Technical Reports Server (NTRS)

Vinokur, M.

1983-01-01

The class of one-dimensional stretching functions used in finite-difference calculations is studied. For solutions containing a highly localized region of rapid variation, simple criteria for a stretching function are derived using a truncation error analysis. These criteria are used to investigate two types of stretching functions. One an interior stretching function, for which the location and slope of an interior clustering region are specified. The simplest such function satisfying the criteria is found to be one based on the inverse hyperbolic sine. The other type of function is a two-sided stretching function, for which the arbitrary slopes at the two ends of the one-dimensional interval are specified. The simplest such general function is found to be one based on the inverse tangent. Previously announced in STAR as N80-25055

Cyclic stretch induces cyclooxygenase-2 gene expression in vascular endothelial cells via activation of nuclear factor kappa-{beta}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhao, Haige; Hiroi, Toyoko; Hansen, Baranda S.

2009-11-27

Vascular endothelial cells respond to biomechanical forces, such as cyclic stretch and shear stress, by altering gene expression. Since endothelial-derived prostanoids, such as prostacyclin and thromboxane A{sub 2}, are key mediators of endothelial function, we investigated the effects of cyclic stretch on the expression of genes in human umbilical vein endothelial cells controlling prostanoid synthesis: cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2), prostacyclin synthase (PGIS) and thromboxane A{sub 2} synthase (TXAS). COX-2 and TXAS mRNAs were upregulated by cyclic stretch for 24 h. In contrast, PGIS mRNA was decreased and stretch had no effect on COX-1 mRNA expression. We further show that stretch-inducedmore » upregulation of COX-2 is mediated by activation of the NF-{kappa}{beta} signaling pathway.« less

Influence of UV and Gamma radiations on the induced birefringence of stretched poly(vinyl) alcohol foils

NASA Astrophysics Data System (ADS)

Nechifor, Cristina-Delia; Zelinschi, Carmen Beatrice; Dorohoi, Dana-Ortansa

2014-03-01

The aim of our paper is to evidence the influence of Gamma and UV radiations on the induced birefringence of poly(vinyl alcohol) stretched foils. Thin foils of PVA were prepared and dried without modifying their surfaces. The polymeric foils were irradiated from 15 min to 6 h using UV and Gamma radiations. The induced by stretching under heating birefringence of PVA films was measured at λ = 589.3 nm with a Babinet Compensator. Physico-chemical processes (photo stabilization, photo degradation, oxidation) induced by irradiation of polymer matrix influence both the stretching degree and the anisotropy of etired foils. An increase of birefringence versus the stretching ratio of the PVA foils was evidenced for all studied samples. The dependence of the birefringence on the exposure time, stretching ratio and nature of radiation was also confirmed.

Immediate combined effect of gastrocnemius stretching and sustained talocrural joint mobilization in individuals with limited ankle dorsiflexion: A randomized controlled trial.

PubMed

Kang, Min-Hyeok; Oh, Jae-Seop; Kwon, Oh-Yun; Weon, Jong-Hyuk; An, Duk-Hyun; Yoo, Won-Gyu

2015-12-01

Although gastrocnemius stretching and talocrural joint mobilization have been suggested as effective interventions to address limited ankle dorsiflexion passive range of motion (DF PROM), the effects of a combination of the two interventions have not been identified. The aim of the present study was to compare the effects of gastrocnemius stretching combined with joint mobilization and gastrocnemius stretching alone. A randomized controlled trial. In total, 24 individuals with limited ankle DF PROM were randomized to undergo gastrocnemius stretching combined with joint mobilization (12 feet in 12 individuals) or gastrocnemius stretching alone (12 feet in 12 individuals) for 5 min. Ankle kinematics during gait (time to heel-off and ankle DF before heel-off), ankle DF PROM, posterior talar glide, and displacement of the myotendinous junction (MTJ) of the gastrocnemius were assessed before and after the interventions. The groups were compared using two-way repeated measures analysis of variance. Greater increases in the time to heel-off and ankle DF before heel-off during gait and posterior talar glide were observed in the stretching combined with joint mobilization group versus the stretching alone group. Ankle DF PROM and displacement of the MTJ of the gastrocnemius were increased significantly after the interventions in both groups, with no significant difference between them. These findings suggest that gastrocnemius stretching with joint mobilization needs to be considered to improve ankle kinematics during gait. Copyright © 2015 Elsevier Ltd. All rights reserved.

The influence of foot position on stretching of the plantar fascia.

PubMed

Flanigan, Ryan M; Nawoczenski, Deborah A; Chen, Linlin; Wu, Hulin; DiGiovanni, Benedict F

2007-07-01

A recent study found nonweightbearing stretching exercises specific to the plantar fascia to be superior to the standard program of weightbearing Achilles tendon-stretching exercises in patients with chronic plantar fasciitis. The present study used a cadaver model to demonstrate the influence of foot and ankle position on stretching of the plantar fascia. Twelve fresh-frozen lower-leg specimens were tested in 15 different configurations representing various combinations of ankle and metatarsophalangeal (MTP) joint dorsiflexion, midtarsal transverse plane abduction and adduction, and forefoot varus and valgus. Measurements were recorded by a differential variable reluctance transducer (DVRT) implanted into the medial band of the plantar fascia, and primary measurement was a percent deformation of the plantar fascia (stretch) with respect to a reference position (90 degrees ankle dorsiflexion, 0 degrees midtarsal and forefoot orientation, and 0 degrees MTP dorsiflexion). Ankle and MTP joint dorsiflexion produced a significant increase (14.91%) in stretch compared to the position of either ankle dorsiflexion alone (9.31% increase, p < 0.001) or MTP dorsiflexion alone (7.33% increase, p < 0.01). There was no significant increase in stretch with positions of abduction or varus (2.49%, p = 0.27 and 0.55%, p = 0.79). This study provides a mechanical explanation for enhanced outcomes in recent clinical trials using plantar fascia tissue-specific stretching exercises and lends support to the use of ankle and MTP joint dorsiflexion when employing stretching protocols for nonoperative treatment in patients with chronic proximal plantar fasciitis.

The direction of stretch-induced cell and stress fiber orientation depends on collagen matrix stress.

PubMed

Tondon, Abhishek; Kaunas, Roland

2014-01-01

Cell structure depends on both matrix strain and stiffness, but their interactive effects are poorly understood. We investigated the interactive roles of matrix properties and stretching patterns on cell structure by uniaxially stretching U2OS cells expressing GFP-actin on silicone rubber sheets supporting either a surface-adsorbed coating or thick hydrogel of type-I collagen. Cells and their actin stress fibers oriented perpendicular to the direction of cyclic stretch on collagen-coated sheets, but oriented parallel to the stretch direction on collagen gels. There was significant alignment parallel to the direction of a steady increase in stretch for cells on collagen gels, while cells on collagen-coated sheets did not align in any direction. The extent of alignment was dependent on both strain rate and duration. Stretch-induced alignment on collagen gels was blocked by the myosin light-chain kinase inhibitor ML7, but not by the Rho-kinase inhibitor Y27632. We propose that active orientation of the actin cytoskeleton perpendicular and parallel to direction of stretch on stiff and soft substrates, respectively, are responses that tend to maintain intracellular tension at an optimal level. Further, our results indicate that cells can align along directions of matrix stress without collagen fibril alignment, indicating that matrix stress can directly regulate cell morphology.

Feedback-controlled and programmed stretching of the ankle plantarflexors and dorsiflexors in stroke: effects of a 4-week intervention program.

PubMed

Selles, Ruud W; Li, Xiaoyan; Lin, Fang; Chung, Sun G; Roth, Elliot J; Zhang, Li-Qun

2005-12-01

To investigate the effect of repeated feedback-controlled and programmed "intelligent" stretching of the ankle plantar- and dorsiflexors to treat subjects with ankle spasticity and/or contracture in stroke. Noncontrolled trial. Institutional research center. Subjects with spasticity and/or contracture after stroke. Stretching of the plantar- and dorsiflexors of the ankle 3 times a week for 45 minutes during a 4-week period by using a feedback-controlled and programmed stretching device. Passive and active range of motion (ROM), muscle strength, joint stiffness, joint viscous damping, reflex excitability, comfortable walking speed, and subjective experiences of the subjects. Significant improvements were found in the passive ROM, maximum voluntary contraction, ankle stiffness, and comfortable walking speed. The visual analog scales indicated very positive subjective evaluation in terms of the comfort of stretching and the effect on their involved ankle. Repeated feedback-controlled or intelligent stretching had a positive influence on the joint properties of the ankle with spasticity and/or contracture after stroke. The stretching device may be an effective and safe alternative to manual passive motion treatment by a therapist and has potential to be used to repeatedly and regularly stretch the ankle of subjects with spasticity and/or contracture without daily involvement of clinicians or physical therapists.

Effects of Stretching Speed on Mechanical Rupture of Phospholipid/Cholesterol Bilayers: Molecular Dynamics Simulation

PubMed Central

Shigematsu, Taiki; Koshiyama, Kenichiro; Wada, Shigeo

2015-01-01

Rupture of biological cell membrane under mechanical stresses is critical for cell viability. It is triggered by local rearrangements of membrane molecules. We investigated the effects of stretching speed on mechanical rupture of phospholipid/cholesterol bilayers using unsteady molecular dynamics simulations. We focused on pore formation, the trigger of rupture, in a 40 mol% cholesterol-including bilayer. The unsteady stretching was modeled by proportional and temporal scaling of atom positions at stretching speeds from 0.025 to 30 m/s. The effects of the stretching speed on the critical areal strain, where the pore forms, is composed of two regimes. At low speeds (<1.0 m/s), the critical areal strain is insensitive to speed, whereas it significantly increases at higher speeds. Also, the strain is larger than that of a pure bilayer, regardless of the stretching speeds, which qualitatively agrees with available experimental data. Transient recovery of the cholesterol and phospholipid molecular orientations was evident at lower speeds, suggesting the formation of a stretch-induced interdigitated gel-like phase. However, this recovery was not confirmed at higher speeds or for the pure bilayer. The different responses of the molecular orientations may help explain the two regimes for the effect of stretching speed on pore formation. PMID:26471872

Eliminating electromechanical instability in dielectric elastomers by employing pre-stretch

NASA Astrophysics Data System (ADS)

Jiang, Liang; Betts, Anthony; Kennedy, David; Jerrams, Stephen

2016-07-01

Electromechanical instability (EMI) is one of most common failure modes for dielectric elastomers (DEs). It has been reported that pre-stretching a DE sample can suppress EMI due to strain stiffening taking place for larger strains and a higher elastic modulus are achieved at high stretch ratios when a voltage is applied to the material. In this work, the influence of equi-biaxial stretch on DE secant modulus was studied using VHB 4910 and silicone rubber (SR) composites containing barium titanate (BaTiO3, BT) particles and also dopamine coated BT (DP-BT) particles. The investigation of equi-biaxial deformation and EMI failure for VHB 4910 was undertaken by introducing a voltage-stretch function. The results showed that EMI was suppressed by equi-biaxial pre-stretch for all the DEs fabricated and tested. The stiffening properties of the DE materials were also studied with respect to the secant modulus. Furthermore, a voltage-induced strain of above 200% was achieved for the polyacrylate film by applying a pre-stretch ratio of 2.0 without EMI occurring. However, a maximum voltage-induced strain in the polyacrylate film of 78% was obtained by the SR/20 wt% DP-BT composite for a lower applied pre-stretch ratio of 1.6 and again EMI was eliminated.

Stretching Micropatterned Cells on a PDMS Membrane

PubMed Central

Carpi, Nicolas; Piel, Matthieu

2014-01-01

Mechanical forces exerted on cells and/or tissues play a major role in numerous processes. We have developed a device to stretch cells plated on a PolyDiMethylSiloxane (PDMS) membrane, compatible with imaging. This technique is reproducible and versatile. The PDMS membrane can be micropatterned in order to confine cells or tissues to a specific geometry. The first step is to print micropatterns onto the PDMS membrane with a deep UV technique. The PDMS membrane is then mounted on a mechanical stretcher. A chamber is bound on top of the membrane with biocompatible grease to allow gliding during the stretch. The cells are seeded and allowed to spread for several hours on the micropatterns. The sample can be stretched and unstretched multiple times with the use of a micrometric screw. It takes less than a minute to apply the stretch to its full extent (around 30%). The technique presented here does not include a motorized device, which is necessary for applying repeated stretch cycles quickly and/or computer controlled stretching, but this can be implemented. Stretching of cells or tissue can be of interest for questions related to cell forces, cell response to mechanical stress or tissue morphogenesis. This video presentation will show how to avoid typical problems that might arise when doing this type of seemingly simple experiment. PMID:24514571

The influence of mechanical stretching on mitosis, growth, and adipose conversion in adipocyte cultures.

PubMed

Shoham, Naama; Gefen, Amit

2012-09-01

The mechanotransduction of adipocytes is not well characterized in the literature. In this study, we employ stochastic modeling fitted to experiments for characterizing the influence of mechanical stretching delivered to adipocyte monolayers on the probabilities of commitment to the adipocyte lineage, mitosis, and growth after mitosis in 3T3-L1 adipocytes. We found that the probability of a cell to become committed to the adipocyte lineage in a single division when cultured on an elastic substrate was 0.025, which was indistinguishable between cultures that were radially stretched (to 12% strain) and control cultures. The probability of undergoing mitosis however was different between the groups, being 0.4 in the stretched cultures and 0.6 in the controls. The probability of growing after mitosis was affected by the stretching as well and was 0.9 and 0.8 in the stretched and control groups, respectively. We conclude that static stretching of the substrate of adipocyte cultures influences the mitotic potential of the cells as well as the growth potential post-mitosis. The present work provides better understanding of the mechanotransduction of adipocytes and in particular quantify how stretching influences the likelihood of cell proliferation and differentiation and, consequently, adipogenesis in the adipocyte cultures.

Stretching human mesenchymal stromal cells on stiffness-customized collagen type I generates a smooth muscle marker profile without growth factor addition

NASA Astrophysics Data System (ADS)

Rothdiener, Miriam; Hegemann, Miriam; Uynuk-Ool, Tatiana; Walters, Brandan; Papugy, Piruntha; Nguyen, Phong; Claus, Valentin; Seeger, Tanja; Stoeckle, Ulrich; Boehme, Karen A.; Aicher, Wilhelm K.; Stegemann, Jan P.; Hart, Melanie L.; Kurz, Bodo; Klein, Gerd; Rolauffs, Bernd

2016-10-01

Using matrix elasticity and cyclic stretch have been investigated for inducing mesenchymal stromal cell (MSC) differentiation towards the smooth muscle cell (SMC) lineage but not in combination. We hypothesized that combining lineage-specific stiffness with cyclic stretch would result in a significantly increased expression of SMC markers, compared to non-stretched controls. First, we generated dense collagen type I sheets by mechanically compressing collagen hydrogels. Atomic force microscopy revealed a nanoscale stiffness range known to support myogenic differentiation. Further characterization revealed viscoelasticity and stable biomechanical properties under cyclic stretch with >99% viable adherent human MSC. MSCs on collagen sheets demonstrated a significantly increased mRNA but not protein expression of SMC markers, compared to on culture flasks. However, cyclic stretch of MSCs on collagen sheets significantly increased both mRNA and protein expression of α-smooth muscle actin, transgelin, and calponin versus plastic and non-stretched sheets. Thus, lineage-specific stiffness and cyclic stretch can be applied together for inducing MSC differentiation towards SMCs without the addition of recombinant growth factors or other soluble factors. This represents a novel stimulation method for modulating the phenotype of MSCs towards SMCs that could easily be incorporated into currently available methodologies to obtain a more targeted control of MSC phenotype.

The effect of age on hamstring passive properties after a 10-week stretch training

PubMed Central

Haab, Thomas; Wydra, Georg

2017-01-01

[Purpose] Degenerative changes take place in the musculoskeletal system of elderly people, resulting in a reduced range of motion. For this reason, stretch training is recommended for elderly individuals. To date, there have been no studies of the adaptations of the passive properties of muscles following long-term stretch training. The aim of this study is to investigate the hamstring elasticity of elderly people following a 10-week stretch training and compare the results to a younger cohort. [Subjects and Methods] The experimental groups consisted of 15 younger (24.0 ± 4.0 years) and 14 older (65.1 ± 7.9 years) individuals. Both experimental groups undertook a standardised 10-week static passive hamstring stretch training. Passive properties of the hamstring were measured with an instrumented Straight Leg Raise Test. [Results] After a 10-week stretch training, there were increases in range of motion, passive resistive force and passive elastic energy in both age groups. Passive elastic stiffness decreased. Changes of hamstring passive properties did not differ significantly between age groups after a 10-week stretch training. [Conclusion] Increasing age has a negative effect on muscle passive properties, but older individuals benefit from regular stretch training, just as younger individuals do. PMID:28626322

Data error and highly parameterized groundwater models

USGS Publications Warehouse

Hill, M.C.

2008-01-01

Strengths and weaknesses of highly parameterized models, in which the number of parameters exceeds the number of observations, are demonstrated using a synthetic test case. Results suggest that the approach can yield close matches to observations but also serious errors in system representation. It is proposed that avoiding the difficulties of highly parameterized models requires close evaluation of: (1) model fit, (2) performance of the regression, and (3) estimated parameter distributions. Comparisons to hydrogeologic information are expected to be critical to obtaining credible models. Copyright ?? 2008 IAHS Press.

A scheme for parameterizing ice cloud water content in general circulation models

NASA Technical Reports Server (NTRS)

Heymsfield, Andrew J.; Donner, Leo J.

1989-01-01

A method for specifying ice water content in GCMs is developed, based on theory and in-cloud measurements. A theoretical development of the conceptual precipitation model is given and the aircraft flights used to characterize the ice mass distribution in deep ice clouds is discussed. Ice water content values derived from the theoretical parameterization are compared with the measured values. The results demonstrate that a simple parameterization for atmospheric ice content can account for ice contents observed in several synoptic contexts.

Ultrafast dynamics of liquid water: Frequency fluctuations of the OH stretch and the HOH bend

DOE Office of Scientific and Technical Information (OSTI.GOV)

Imoto, Sho; Xantheas, Sotiris S.; Saito, Shinji

2013-07-28

Frequency fluctuations of the OH stretch and the HOH bend in liquid water are reported from the third-order response function evaluated using the TTM3-F potential for water. The simulated two-dimensional infrared (IR) spectra of the OH stretch are similar to previously reported theoretical results. The present study suggests that the frequency fluctuation of the HOH bend is faster than that of the OH stretch. The ultrafast loss of the frequency correlation of the HOH bend is due to the strong couplings with the OH stretch as well as the intermolecular hydrogen bond bend.

Go4Life:Flexibility | NIH MedlinePlus the Magazine

MedlinePlus

... Upper Arm How Much, How Often Do each stretching exercise 3 to 5 times at each session. ... lower-back flexibility exercises. Always warm up before stretching exercises. Stretching your muscles before they are warmed ...

Exercise and age

MedlinePlus

... down the stairs STRETCHING Stretching can help your body stay flexible. To stay limber: Learn shoulder, upper arm, and calf stretches Take yoga classes Do everyday activities, such as making your bed or bending over to tie your shoes

Elastic full-waveform inversion and parameterization analysis applied to walk-away vertical seismic profile data for unconventional (heavy oil) reservoir characterization

NASA Astrophysics Data System (ADS)

Pan, Wenyong; Innanen, Kristopher A.; Geng, Yu

2018-03-01

Seismic full-waveform inversion (FWI) methods hold strong potential to recover multiple subsurface elastic properties for hydrocarbon reservoir characterization. Simultaneously updating multiple physical parameters introduces the problem of interparameter tradeoff, arising from the covariance between different physical parameters, which increases nonlinearity and uncertainty of multiparameter FWI. The coupling effects of different physical parameters are significantly influenced by model parameterization and acquisition arrangement. An appropriate choice of model parameterization is critical to successful field data applications of multiparameter FWI. The objective of this paper is to examine the performance of various model parameterizations in isotropic-elastic FWI with walk-away vertical seismic profile (W-VSP) dataset for unconventional heavy oil reservoir characterization. Six model parameterizations are considered: velocity-density (α, β and ρ΄), modulus-density (κ, μ and ρ), Lamé-density (λ, μ΄ and ρ‴), impedance-density (IP, IS and ρ″), velocity-impedance-I (α΄, β΄ and I_P^'), and velocity-impedance-II (α″, β″ and I_S^'). We begin analyzing the interparameter tradeoff by making use of scattering radiation patterns, which is a common strategy for qualitative parameter resolution analysis. In this paper, we discuss the advantages and limitations of the scattering radiation patterns and recommend that interparameter tradeoffs be evaluated using interparameter contamination kernels, which provide quantitative, second-order measurements of the interparameter contaminations and can be constructed efficiently with an adjoint-state approach. Synthetic W-VSP isotropic-elastic FWI experiments in the time domain verify our conclusions about interparameter tradeoffs for various model parameterizations. Density profiles are most strongly influenced by the interparameter contaminations; depending on model parameterization, the inverted density profile can be over-estimated, under-estimated or spatially distorted. Among the six cases, only the velocity-density parameterization provides stable and informative density features not included in the starting model. Field data applications of multicomponent W-VSP isotropic-elastic FWI in the time domain were also carried out. The heavy oil reservoir target zone, characterized by low α-to-β ratios and low Poisson's ratios, can be identified clearly with the inverted isotropic-elastic parameters.

Elastic full-waveform inversion and parameterization analysis applied to walk-away vertical seismic profile data for unconventional (heavy oil) reservoir characterization

DOE PAGES

Pan, Wenyong; Innanen, Kristopher A.; Geng, Yu

2018-03-06

We report seismic full-waveform inversion (FWI) methods hold strong potential to recover multiple subsurface elastic properties for hydrocarbon reservoir characterization. Simultaneously updating multiple physical parameters introduces the problem of interparameter tradeoff, arising from the covariance between different physical parameters, which increases nonlinearity and uncertainty of multiparameter FWI. The coupling effects of different physical parameters are significantly influenced by model parameterization and acquisition arrangement. An appropriate choice of model parameterization is critical to successful field data applications of multiparameter FWI. The objective of this paper is to examine the performance of various model parameterizations in isotropic-elastic FWI with walk-away vertical seismicmore » profile (W-VSP) dataset for unconventional heavy oil reservoir characterization. Six model parameterizations are considered: velocity-density (α, β and ρ'), modulus-density (κ, μ and ρ), Lamé-density (λ, μ' and ρ'''), impedance-density (IP, IS and ρ''), velocity-impedance-I (α', β' and I' P), and velocity-impedance-II (α'', β'' and I'S). We begin analyzing the interparameter tradeoff by making use of scattering radiation patterns, which is a common strategy for qualitative parameter resolution analysis. In this paper, we discuss the advantages and limitations of the scattering radiation patterns and recommend that interparameter tradeoffs be evaluated using interparameter contamination kernels, which provide quantitative, second-order measurements of the interparameter contaminations and can be constructed efficiently with an adjoint-state approach. Synthetic W-VSP isotropic-elastic FWI experiments in the time domain verify our conclusions about interparameter tradeoffs for various model parameterizations. Density profiles are most strongly influenced by the interparameter contaminations; depending on model parameterization, the inverted density profile can be over-estimated, under-estimated or spatially distorted. Among the six cases, only the velocity-density parameterization provides stable and informative density features not included in the starting model. Field data applications of multicomponent W-VSP isotropic-elastic FWI in the time domain were also carried out. Finally, the heavy oil reservoir target zone, characterized by low α-to-β ratios and low Poisson’s ratios, can be identified clearly with the inverted isotropic-elastic parameters.« less