Difficult to control atopic dermatitis
2013-01-01
Difficult to control atopic dermatitis (AD) presents a therapeutic challenge and often requires combinations of topical and systemic treatment. Anti-inflammatory treatment of severe AD most commonly includes topical glucocorticosteroids and topical calcineurin antagonists used for exacerbation management and more recently for proactive therapy in selected cases. Topical corticosteroids remain the mainstay of therapy, the topical calcineurin inhibitors tacrolimus and pimecrolimus are preferred in certain locations. Systemic anti-inflammatory treatment is an option for severe refractory cases. Microbial colonization and superinfection contribute to disease exacerbation and thus justify additional antimicrobial / antiseptic treatment. Systemic antihistamines (H1) may relieve pruritus but do not have sufficient effect on eczema. Adjuvant therapy includes UV irradiation preferably of UVA1 wavelength. “Eczema school” educational programs have been proven to be helpful. PMID:23663504
1988-01-01
system requirements, design guidelines, and interface requirements has been prepared and included as Volume II of this Task 1 topical report. The Volume ...WAESD-TR-88-0002 Conceptual Design Of A Space-Based Multimegawatt MHD Power System ffA«kjjjjjTfc Task 1 Topical Report Volume I: Technical...Space-Based Multimegawatt MHD Power System: Task 1 Topical Report, Volume I: Technical Discussion Personal Author: Dana, RA. Corporate Author Or
ERIC Educational Resources Information Center
Birch, Sandra K.; Pettus, Alvin M.
Various topics on water and water conservation are discussed, each general topic followed by a student activity. Topics include: (1) importance of water; (2) water in the environment; (3) getting water to and from homes (making water usable; treating wastewater; on-site systems, including water wells and septic tanks); (4) relationship between…
Revealing Learner Interests through Topic Mining from Question-Answering Data
ERIC Educational Resources Information Center
Dun, Yijie; Wang, Na; Wang, Min; Hao, Tianyong
2017-01-01
In a question-answering system, learner generated content including asked and answered questions is a meaningful resource to capture learning interests. This paper proposes an approach based on question topic mining for revealing learners' concerned topics in real community question-answering systems. The authors' approach firstly preprocesses all…
Energy Education in Elementary Social Studies. Holt Databank System.
ERIC Educational Resources Information Center
Minnesota State Energy Agency, St. Paul.
This document provides elementary teachers with an annotated index according to grade levels 1-6 of energy education topics in the "Holt Databank System" (Holt, Rinehart and Winston), followed by suggestions for activities related to the topics. Indexed topics, which comprise a major portion of the document, include basic energy information,…
Systemic and topical drugs for aging skin.
Kockaert, Michael; Neumann, Martino
2003-08-01
The rejuvenation of aging skin is a common desire for our patients, and several options are available. Although there are some systemic methods, the most commonly used treatments for rejuvenation of the skin are applied topically. The most frequently used topical drugs include retinoids, alpha hydroxy acids (AHAs), vitamin C, beta hydroxy acids, anti-oxidants, and tocopherol. Combination therapy is frequently used; particularly common is the combination of retinoids and AHAs. Systemic therapies available include oral retinoids and vitamin C. Other available therapies such as chemical peels, face-lifts, collagen, and botulinum toxin injections are not discussed in this article.
Second CLIPS Conference Proceedings, volume 1
NASA Technical Reports Server (NTRS)
Giarratano, Joseph (Editor); Culbert, Christopher J. (Editor)
1991-01-01
Topics covered at the 2nd CLIPS Conference held at the Johnson Space Center, September 23-25, 1991 are given. Topics include rule groupings, fault detection using expert systems, decision making using expert systems, knowledge representation, computer aided design and debugging expert systems.
NASA Technical Reports Server (NTRS)
Marshall, Jospeh R.; Morris, Allan T.
2007-01-01
Since 2003, AIAA's Computer Systems and Software Systems Technical Committees (TCs) have developed a database that aids technical committee management to map technical topics to their members. This Topics/Interest (T/I) database grew out of a collection of charts and spreadsheets maintained by the TCs. Since its inception, the tool has evolved into a multi-dimensional database whose dimensions include the importance, interest and expertise of TC members and whether or not a member and/or a TC is actively involved with the topic. In 2005, the database was expanded to include the TCs in AIAA s Information Systems Group and then expanded further to include all AIAA TCs. It was field tested at an AIAA Technical Activities Committee (TAC) Workshop in early 2006 through live access by over 80 users. Through the use of the topics database, TC and program committee (PC) members can accomplish relevant tasks such as: to identify topic experts (for Aerospace America articles or external contacts), to determine the interest of its members, to identify overlapping topics between diverse TCs and PCs, to guide new member drives and to reveal emerging topics. This paper will describe the origins, inception, initial development, field test and current version of the tool as well as elucidate the benefits and insights gained by using the database to aid the management of various TC functions. Suggestions will be provided to guide future development of the database for the purpose of providing dynamics and system level benefits to AIAA that currently do not exist in any technical organization.
Concepts in Electromagnetic Scattering for Particulate-Systems Characterization
2013-04-29
scientists attended and 19 presentations were given. Specific topics included remote sensing, polarimetry , analytic and numeric electromagnetic...presentations were given. Specific topics included remote sensing, polarimetry , ana- lytic and numeric electromagnetic theory, camouflage in nature
Space station data system analysis/architecture study. Task 3: Trade studies, DR-5, volume 1
NASA Technical Reports Server (NTRS)
1985-01-01
The primary objective of Task 3 is to provide additional analysis and insight necessary to support key design/programmatic decision for options quantification and selection for system definition. This includes: (1) the identification of key trade study topics; (2) the definition of a trade study procedure for each topic (issues to be resolved, key inputs, criteria/weighting, methodology); (3) conduct tradeoff and sensitivity analysis; and (4) the review/verification of results within the context of evolving system design and definition. The trade study topics addressed in this volume include space autonomy and function automation, software transportability, system network topology, communications standardization, onboard local area networking, distributed operating system, software configuration management, and the software development environment facility.
ERIC Educational Resources Information Center
Ministry of Foreign Affairs, Tokyo (Japan).
Following an introduction which discusses the history and geography of Japan, this book focuses on topics related to this country's government, economy, social conditions, and cultural life. Topics related to government include: constitution and emperor; legislature; executive power; judiciary system; foreign relations; and defense. Topics related…
The Third NASA Goddard Conference on Mass Storage Systems and Technologies
NASA Technical Reports Server (NTRS)
Kobler, Benjamin (Editor); Hariharan, P. C. (Editor)
1993-01-01
This report contains copies of nearly all of the technical papers and viewgraphs presented at the Goddard Conference on Mass Storage Systems and Technologies held in October 1993. The conference served as an informational exchange forum for topics primarily relating to the ingestion and management of massive amounts of data and the attendant problems involved. Discussion topics include the necessary use of computers in the solution of today's infinitely complex problems, the need for greatly increased storage densities in both optical and magnetic recording media, currently popular storage media and magnetic media storage risk factors, data archiving standards including a talk on the current status of the IEEE Storage Systems Reference Model (RM). Additional topics addressed System performance, data storage system concepts, communications technologies, data distribution systems, data compression, and error detection and correction.
Research in Optical Symbolic Tasks
1989-11-29
November 1989. Specifically, we have concentrated on the following topics: complexity studies for optical neural and digital systems, architecture and...1989. Specifically, we hav, concentrated on the following topics: complexity studies for optical neural and digital systems, architecture and models for...Digital Systems 1.1 Digital Optical Parallel System Complexity Our study of digital optical system complexity has included a comparison of optical and
Finasteride topical delivery systems for androgenetic alopecia.
Khan, Muhammad Zia Ullah; Khan, Shujaat Ali; Ubaid, Muhammad; Shah, Aamna; Kousar, Rozina; Murtaza, Ghulam
2018-01-23
Androgenetic alopecia, generally recognized as male pattern baldness, is a gradually developing medical and physiological change, which is manifested by continuous hair-loss from scalp. Finasteride (4-aza-3-oxosteroid) is a potent anti-baldness compound that selectively and competitively inhibits the 5α-reductase isoenzymes. Prolonged oral use of finasteride leads to the emergence of sexual disorders including decrease in libido, gynecomastia, erectile dysfunction, ejaculation disorder, orgasm disorders and mood disturbances. Since, hair follicles widely home in 5α-reductase, topical formulations of finasteride in comparison to its oral formulations are expected to potentially reduce its systemic adverse effects. The analysis of literature has revealed some delivery systems developed for the enhanced and localized penetration of finasteride into the skin. These finasteride delivery systems include polymersomes, vesicular nanocarriers, vesicular ethosomal carriers, liposomes and niosomes, liquid crystalline nanoparticles, topical solutions and gels. The aim of this review article is to briefly amass all literature on topical delivery of finasteride to elaborate best dosage form, i.e. formulation having maximum permeation rate. This study will serve as a future perspective regarding topical delivery of finasteride. The literature analysis has exhibited that most of the previous investigators have used propylene glycol in their finasteride-loaded topical formulations, while poloxamer P407, monoolein, transcutol P and choline was used in few formulations. Moreover among all drug delivery systems, finasteride liposomal gel system consisting of 2% methyl cellulose and gel system containing poloxamer P407 exhibited the highest flux with a value of 28.4 ± 1.3 µg/cm2h and 23.1 ± 1.4 µg/cm2h, respectively. Several topical drug delivery techniques such as topical microneedles, aerosol foams, nanoemulsions, microsponges, and emulsifier free formulations, fullerenes, ointments, pastes, creams, gel and lotions are still to be worthy regarding finasteride topical delivery in future. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
Bachu, Rinda Devi; Chowdhury, Pallabitha; Al-Saedi, Zahraa H F; Karla, Pradeep K; Boddu, Sai H S
2018-02-27
Ocular drug delivery is challenging due to the presence of anatomical and physiological barriers. These barriers can affect drug entry into the eye following multiple routes of administration (e.g., topical, systemic, and injectable). Topical administration in the form of eye drops is preferred for treating anterior segment diseases, as it is convenient and provides local delivery of drugs. Major concerns with topical delivery include poor drug absorption and low bioavailability. To improve the bioavailability of topically administered drugs, novel drug delivery systems are being investigated. Nanocarrier delivery systems demonstrate enhanced drug permeation and prolonged drug release. This review provides an overview of ocular barriers to anterior segment delivery, along with ways to overcome these barriers using nanocarrier systems. The disposition of nanocarriers following topical administration, their safety, toxicity and clinical trials involving nanocarrier systems are also discussed.
Bachu, Rinda Devi; Chowdhury, Pallabitha; Al-Saedi, Zahraa H. F.; Karla, Pradeep K.; Boddu, Sai H. S.
2018-01-01
Ocular drug delivery is challenging due to the presence of anatomical and physiological barriers. These barriers can affect drug entry into the eye following multiple routes of administration (e.g., topical, systemic, and injectable). Topical administration in the form of eye drops is preferred for treating anterior segment diseases, as it is convenient and provides local delivery of drugs. Major concerns with topical delivery include poor drug absorption and low bioavailability. To improve the bioavailability of topically administered drugs, novel drug delivery systems are being investigated. Nanocarrier delivery systems demonstrate enhanced drug permeation and prolonged drug release. This review provides an overview of ocular barriers to anterior segment delivery, along with ways to overcome these barriers using nanocarrier systems. The disposition of nanocarriers following topical administration, their safety, toxicity and clinical trials involving nanocarrier systems are also discussed. PMID:29495528
Goddard Conference on Mass Storage Systems and Technologies, Volume 1
NASA Technical Reports Server (NTRS)
Kobler, Ben (Editor); Hariharan, P. C. (Editor)
1993-01-01
Copies of nearly all of the technical papers and viewgraphs presented at the Goddard Conference on Mass Storage Systems and Technologies held in Sep. 1992 are included. The conference served as an informational exchange forum for topics primarily relating to the ingestion and management of massive amounts of data and the attendant problems (data ingestion rates now approach the order of terabytes per day). Discussion topics include the IEEE Mass Storage System Reference Model, data archiving standards, high-performance storage devices, magnetic and magneto-optic storage systems, magnetic and optical recording technologies, high-performance helical scan recording systems, and low end helical scan tape drives. Additional topics addressed the evolution of the identifiable unit for processing purposes as data ingestion rates increase dramatically, and the present state of the art in mass storage technology.
User Participation and Participatory Design: Topics in Computing Education.
ERIC Educational Resources Information Center
Kautz, Karlheinz
1996-01-01
Discusses user participation and participatory design in the context of formal education for computing professionals. Topics include the current curriculum debate; mathematical- and engineering-based education; traditional system-development training; and an example of a course program that includes computers and society, and prototyping. (53…
Relevance and Retrieval Evaluation: Perspectives from Medicine.
ERIC Educational Resources Information Center
Hersh, William
1994-01-01
Discusses topical relevance and situational relevance, which takes into account the impact of the retrieval system on the user, in the context of medicine. Topics addressed include scientific validity; limitations of current evaluation methodology, including recall and precision; and a framework for future retrieval research based on an…
Prescription Drug Abuse Information in D.A.R.E.
ERIC Educational Resources Information Center
Morris, Melissa C.; Cline, Rebecca J. Welch; Weiler, Robert M.; Broadway, S. Camille
2006-01-01
This investigation was designed to examine prescription drug-related content and learning objectives in Drug Abuse Resistance Education (D.A.R.E.) for upper elementary and middle schools. Specific prescription-drug topics and context associated with content and objectives were coded. The coding system for topics included 126 topics organized…
Cataloging Expert Systems: Optimism and Frustrated Reality.
ERIC Educational Resources Information Center
Olmstadt, William J.
2000-01-01
Discusses artificial intelligence and attempts to catalog expert systems. Topics include the nature of expertise; examples of cataloging expert systems; barriers to implementation; and problems, including total automation, cataloging expertise, priorities, and system design. (LRW)
NASA Technical Reports Server (NTRS)
Dongarra, Jack (Editor); Messina, Paul (Editor); Sorensen, Danny C. (Editor); Voigt, Robert G. (Editor)
1990-01-01
Attention is given to such topics as an evaluation of block algorithm variants in LAPACK and presents a large-grain parallel sparse system solver, a multiprocessor method for the solution of the generalized Eigenvalue problem on an interval, and a parallel QR algorithm for iterative subspace methods on the CM2. A discussion of numerical methods includes the topics of asynchronous numerical solutions of PDEs on parallel computers, parallel homotopy curve tracking on a hypercube, and solving Navier-Stokes equations on the Cedar Multi-Cluster system. A section on differential equations includes a discussion of a six-color procedure for the parallel solution of elliptic systems using the finite quadtree structure, data parallel algorithms for the finite element method, and domain decomposition methods in aerodynamics. Topics dealing with massively parallel computing include hypercube vs. 2-dimensional meshes and massively parallel computation of conservation laws. Performance and tools are also discussed.
Simpson, Eric L; Bruin-Weller, Marjolein; Flohr, Carsten; Ardern-Jones, Michael R; Barbarot, Sebastien; Deleuran, Mette; Bieber, Thomas; Vestergaard, Christian; Brown, Sara J; Cork, Michael J; Drucker, Aaron M; Eichenfield, Lawrence F; Foelster-Holst, Regina; Guttman-Yassky, Emma; Nosbaum, Audrey; Reynolds, Nick J; Silverberg, Jonathan I; Schmitt, Jochen; Seyger, Marieke M B; Spuls, Phyllis I; Stalder, Jean-Francois; Su, John C; Takaoka, Roberto; Traidl-Hoffmann, Claudia; Thyssen, Jacob P; van der Schaft, Jorien; Wollenberg, Andreas; Irvine, Alan D; Paller, Amy S
2017-10-01
Although most patients with atopic dermatitis (AD) are effectively managed with topical medication, a significant minority require systemic therapy. Guidelines for decision making about advancement to systemic therapy are lacking. To guide those considering use of systemic therapy in AD and provide a framework for evaluation before making this therapeutic decision with the patient. A subgroup of the International Eczema Council determined aspects to consider before prescribing systemic therapy. Topics were assigned to expert reviewers who performed a topic-specific literature review, referred to guidelines when available, and provided interpretation and expert opinion. We recommend a systematic and holistic approach to assess patients with severe signs and symptoms of AD and impact on quality of life before systemic therapy. Steps taken before commencing systemic therapy include considering alternate or concomitant diagnoses, avoiding trigger factors, optimizing topical therapy, ensuring adequate patient/caregiver education, treating coexistent infection, assessing the impact on quality of life, and considering phototherapy. Our work is a consensus statement, not a systematic review. The decision to start systemic medication should include assessment of severity and quality of life while considering the individual's general health status, psychologic needs, and personal attitudes toward systemic therapies. Copyright © 2017 American Academy of Dermatology, Inc. All rights reserved.
Development of a Solar System Concept Inventory
NASA Astrophysics Data System (ADS)
Hornstein, Seth D.; Duncan, D.; S, C. A. T.
2009-01-01
Concept inventories can provide useful insight into students’ understanding of key physical concepts. Knowing what your students have learned during a course is a valuable tool for improving your own teaching. Unfortunately, current astronomy concept inventories are not suitable for an introductory solar system course because they either cover too broad of a range of topics (e.g. Astronomy Diagnostic Test) or are too narrowly focused (e.g. Greenhouse Effect Concept Inventory, Lunar Phase Concept Inventory). We have developed the Solar System Concept Inventory (SSCI) to cover those topics commonly taught in an introductory solar system course. The topics included on the SSCI were selected by having faculty identify the key concepts they address when teaching about the solar system. SSCI topics include formation mechanisms, planetary interiors, atmospheric effects, and small solar system bodies. Student interviews were conducted to identify common naive ideas and reasoning difficulties relating to these key topics. Preliminary development of the SSCI was completed at the University of Colorado and involved over 400 students. A larger, national, multi-institutional field test is planned for Spring 2009 as a Collaboration of Astronomy Teaching Scholars (CATS) research project. We present here the results from the preliminary development and proposed changes for the next stage of research. We would like to thank the NSF for funding under Grant No. 0715517, a CCLI Phase III Grant for the Collaboration of Astronomy Teaching Scholars (CATS) Program.
COURSE OUTLINE FOR FIRST SIX WEEKS FOR SCIENCE-LEVEL II, TALENT PRESERVATION CLASSES.
ERIC Educational Resources Information Center
Houston Independent School District, TX.
THE FIRST 6-WEEK UNIT CONCERNS ANIMAL LIFE, AND TOPICS INCLUDE PROTOZOA, INVERTEBRATES, AND VERTEBRATES. UNIT II, "THE HUMAN BODY", INCLUDES BODY SYSTEMS, HEALTH, AND SAFETY. TEXTBOOK REFERENCES, CONTENT OUTLINE, TEACHING SUGGESTIONS, REFERENCE READINGS, AND AUDIOVISUAL AIDS ARE GIVEN UNDER EACH TOPIC. IT IS SUGGESTED THAT FIRST…
Abstracts for the 52nd Annual Meeting of the Meteoritical Society
NASA Technical Reports Server (NTRS)
1989-01-01
Various topics in meteorology are discussed. These topics include chondrites, chondrule, iron and other minerals, impact cratering, lunar studies, early earth and early solar system processes, rare gases and cosmic dust.
NASA Technical Reports Server (NTRS)
Tavenner, Leslie A. (Editor)
1991-01-01
These proceedings overview major space information system projects and lessons learned from current missions. Other topics include the science information system requirements for the 1990s, an information systems design approach for major programs, the technology needs and projections, the standards for space data information systems, the artificial intelligence technology and applications, international interoperability, and spacecraft data systems and architectures advanced communications. Other topics include the software engineering technology and applications, the multimission multidiscipline information system architectures, the distributed planning and scheduling systems and operations, and the computer and information systems architectures. Paper presented include prospects for scientific data analysis systems for solar-terrestrial physics in the 1990s, the Columbus data management system, data storage technologies for the future, the German aerospace research establishment, and launching artificial intelligence in NASA ground systems.
NASA Technical Reports Server (NTRS)
Pordes, Ruth (Editor)
1989-01-01
Papers on real-time computer applications in nuclear, particle, and plasma physics are presented, covering topics such as expert systems tactics in testing FASTBUS segment interconnect modules, trigger control in a high energy physcis experiment, the FASTBUS read-out system for the Aleph time projection chamber, a multiprocessor data acquisition systems, DAQ software architecture for Aleph, a VME multiprocessor system for plasma control at the JT-60 upgrade, and a multiasking, multisinked, multiprocessor data acquisition front end. Other topics include real-time data reduction using a microVAX processor, a transputer based coprocessor for VEDAS, simulation of a macropipelined multi-CPU event processor for use in FASTBUS, a distributed VME control system for the LISA superconducting Linac, a distributed system for laboratory process automation, and a distributed system for laboratory process automation. Additional topics include a structure macro assembler for the event handler, a data acquisition and control system for Thomson scattering on ATF, remote procedure execution software for distributed systems, and a PC-based graphic display real-time particle beam uniformity.
Real-time fault diagnosis for propulsion systems
NASA Technical Reports Server (NTRS)
Merrill, Walter C.; Guo, Ten-Huei; Delaat, John C.; Duyar, Ahmet
1991-01-01
Current research toward real time fault diagnosis for propulsion systems at NASA-Lewis is described. The research is being applied to both air breathing and rocket propulsion systems. Topics include fault detection methods including neural networks, system modeling, and real time implementations.
Topics on Test Methods for Space Systems and Operations Safety: Applicability of Experimental Data
NASA Technical Reports Server (NTRS)
Hirsch, David B.
2009-01-01
This viewgraph presentation reviews topics on test methods for space systems and operations safety through experimentation and analysis. The contents include: 1) Perception of reality through experimentation and analysis; 2) Measurements, methods, and correlations with real life; and 3) Correlating laboratory aerospace materials flammability data with data in spacecraft environments.
Satellite services system analysis study. Volume 1: Executive summary
NASA Technical Reports Server (NTRS)
1981-01-01
Service requirements are considered. Topics include development of on-orbit operations scenarios, service equipment summary, crew interaction, and satellite features facilitating servicing. Service equipment concepts are considered. Topics include payload deployment, close proximity retrieval, on-orbit servicing, backup/contingency, delivery/retrieval of high energy payloads, Earth return, optional service, and advanced capabilities. Program requirements are assessed.
Effluent Monitoring Procedures: Basic Laboratory Skills. Staff Guide for Conducting the Course.
ERIC Educational Resources Information Center
Engel, William T.; And Others
This manual is designed for use by instructors who will have to teach others the basic laboratory skills needed to perform National Pollution Discharge Elimination System (NPDES) Analyses. It includes topics related to the presentation of training courses in which the NPDES analyses would be taught. These topics include: examples of course…
Development of the Solar System Concept Inventory
NASA Astrophysics Data System (ADS)
Hornstein, S.; Prather, E.
2009-12-01
Concept inventories can provide useful insight into students’ understanding of key physical concepts. Knowing what your students have learned during a course is a valuable tool for improving your own teaching. Unfortunately, current astronomy concept inventories are not suitable for an introductory solar system course because they either cover too broad of a range of topics (e.g. Astronomy Diagnostic Test) or are too narrowly focused (e.g. Greenhouse Effect Concept Inventory, Lunar Phase Concept Inventory). We have developed the Solar System Concept Inventory (SSCI) to cover those topics commonly taught in an introductory solar system course. The topics included on the SSCI were selected by having faculty identify the key concepts they address when teaching about the solar system. SSCI topics include formation mechanisms, planetary interiors, atmospheric effects, and small solar system bodies. Student interviews were conducted to identify common naive ideas and reasoning difficulties relating to these key topics. The SSCI has been through two semesters of national, multi-institutional field-testing, involving over 1500 students. After the first semester of testing, question statistics were used to flag ineffective questions and flagged questions were revised or eliminated. We will present an overall outline of the SSCI development as well as our question-flagging criteria and question analyses from the latest round of field-testing. We would like to thank the NSF for funding under Grant No. 0715517, a CCLI Phase III Grant for the Collaboration of Astronomy Teaching Scholars (CATS) Program.
Autonomous Attitude Determination System (AADS). Volume 1: System description
NASA Technical Reports Server (NTRS)
Saralkar, K.; Frenkel, Y.; Klitsch, G.; Liu, K. S.; Lefferts, E.; Tasaki, K.; Snow, F.; Garrahan, J.
1982-01-01
Information necessary to understand the Autonomous Attitude Determination System (AADS) is presented. Topics include AADS requirements, program structure, algorithms, and system generation and execution.
Topics in programmable automation. [for materials handling, inspection, and assembly
NASA Technical Reports Server (NTRS)
Rosen, C. A.
1975-01-01
Topics explored in the development of integrated programmable automation systems include: numerically controlled and computer controlled machining; machine intelligence and the emulation of human-like capabilities; large scale semiconductor integration technology applications; and sensor technology for asynchronous local computation without burdening the executive minicomputer which controls the whole system. The role and development of training aids, and the potential application of these aids to augmented teleoperator systems are discussed.
Evidence-based Danish guidelines for the treatment of Malassezia-related skin diseases.
Hald, Marianne; Arendrup, Maiken C; Svejgaard, Else L; Lindskov, Rune; Foged, Erik K; Saunte, Ditte Marie L
2015-01-01
Internationally approved guidelines for the diagnosis and management of Malassezia-related skin diseases are lacking. Therefore, a panel of experts consisting of dermatologists and a microbiologist under the auspices of the Danish Society of Dermatology undertook a data review and compiled guidelines for the diagnostic procedures and management of pityriasis versicolor, seborrhoeic dermatitis and Malassezia folliculitis. Main recommendations in most cases of pityriasis versicolor and seborrhoeic dermatitis include topical treatment which has been shown to be sufficient. As first choice, treatment should be based on topical antifungal medication. A short course of topical corticosteroid or topical calcineurin inhibitors has an anti-inflammatory effect in seborrhoeic dermatitis. Systemic antifungal therapy may be indicated for widespread lesions or lesions refractory to topical treatment. Maintenance therapy is often necessary to prevent relapses. In the treatment of Malassezia folliculitis systemic antifungal treatment is probably more effective than topical treatment but a combination may be favourable.
Flight Mechanics/Estimation Theory Symposium
NASA Technical Reports Server (NTRS)
1978-01-01
Satellite attitude determination and control, orbit determination, and onboard and ground attitude determination procedures are among the topics discussed. Other topics covered include: effect of atmosphere on Venus orbiter navigation; satellite-to-satellite tracking; and satellite onboard navigation using global positioning system data.
ERIC Educational Resources Information Center
Dalrymple, Prudence W.; Roderer, Nancy K.
1994-01-01
Highlights the changes that have occurred from 1987-93 in database access systems. Topics addressed include types of databases, including CD-ROMs; enduser interface; database selection; database access management, including library instruction and use of primary literature; economic issues; database users; the search process; and improving…
Topical Vasodilators in Microsurgery: What Is the Evidence?
Rinkinen, Jacob; Halvorson, Eric G
2017-01-01
Background Topical vasodilators are frequently used during free tissue transfer to prevent and treat vasospasm and microvascular thrombosis. A variety of agents have been studied and are available, yet most microsurgeons select an agent based on anecdotal evidence or personal training. Our aim was to review the literature on topical vasodilators so microsurgeons can make more informed decisions about which agent to use. Methods A systemic review of the literature was performed on PubMed, EMBASE, and Google Scholar using keywords "topical vasodilator," "antispasmodic," "vasospasm," "free flaps," and "microsurgery." Studies were included if they provided a comparative quantitative assessment of topical vasodilators and were written in English. In vitro, in vivo , and clinical studies were included. Results A total of 15 studies were identified and included in our analysis. The three most common classes of topical vasodilator include local anesthetics, phosphodiesterase inhibitors, and calcium channel blockers (CCBs). Of the most commonly used topical vasodilators, CCBs (nifedipine and verapamil) were most effective followed by papaverine and lidocaine. Conclusion The most effective topical vasodilators appear to be CCBs including nifedipine, nicardipine, and verapamil. Evidence suggests that these agents are more effective than papaverine and lidocaine solutions that are commonly used. Future research should directly compare individual CCBs to assess the most effective agent. Studies to date have focused on vessels other than those used by microsurgeons, and therefore further studies specific to these vessels are warranted. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Topical vs. systemic treatments for acute otitis media.
Thornton, Kathy; Parrish, Francie; Swords, Christine
2011-01-01
Acute otitis media (AOM) is a common condition in children that is often treated with systemic antibiotic therapy; however, research suggests that non-complicated AOM will resolve spontaneously using only eardrops. To determine best practice for the use of systematic antibiotics compared to topical treatment of AOM, a systematic review of evidence was conducted. Cochrane, Medline, CINAHL, and other databases were searched. Inclusion criteria were studies published from 1995-2010 that included children with AOM and were randomized controlled trials (RCTs). Five systematic reviews and five RCTs were included in the review. Current evidence recommends using topical and other alternative approaches for treating non-complicated AOM in children 2 years of age or older; however, many practitioners are not currently following these recommendations for various reasons. Additional research to address these reasons may help determine how to improve practitioner adherence to best practice evidence and guidelines to help reduce the unnecessary use of systemic antibiotics.
A Course in... Topics in Random Media.
ERIC Educational Resources Information Center
Glandt, Eduardo D.
1988-01-01
Describes an engineering course for graduate study in random media. Summarizes random media as bulk properties of ordered and disordered two-phase materials. Gives course outline for one semester. Topics include: disordered systems, microstructure determination, survey of models, connectivity, and effective properties. (MVL)
Distance Learning: What's Holding Back This Boundless Delivery System?
ERIC Educational Resources Information Center
Bruder, Isabelle
1989-01-01
Discusses distance learning, identifies who distance learners may be, and examines issues involved in establishing distance learning systems. Topics discussed include teacher concerns, including job security and certification; curriculum concerns, including state and local requirements and cross-cultural issues; cooperative development,…
Innovative applications of artificial intelligence
NASA Astrophysics Data System (ADS)
Schorr, Herbert; Rappaport, Alain
Papers concerning applications of artificial intelligence are presented, covering applications in aerospace technology, banking and finance, biotechnology, emergency services, law, media planning, music, the military, operations management, personnel management, retail packaging, and manufacturing assembly and design. Specific topics include Space Shuttle telemetry monitoring, an intelligent training system for Space Shuttle flight controllers, an expert system for the diagnostics of manufacturing equipment, a logistics management system, a cooling systems design assistant, and a knowledge-based integrated circuit design critic. Additional topics include a hydraulic circuit design assistant, the use of a connector assembly specification expert system to harness detailed assembly process knowledge, a mixed initiative approach to airlift planning, naval battle management decision aids, an inventory simulation tool, a peptide synthesis expert system, and a system for planning the discharging and loading of container ships.
ERIC Educational Resources Information Center
College and Univ. Computer Users Association, Columbia, SC.
The 36 papers contained in this collection from the College and University Computer Users Conference (CUMREC '93) are grouped under six topic areas. The main subject areas and examples of the topics covered are: (1) computer-based student support systems, including telecounseling and recruiting, a student advising system, the assignment of…
The case for Mars III: Strategies for exploration - General interest and overview
NASA Technical Reports Server (NTRS)
Stoker, Carol R. (Editor)
1989-01-01
Papers on the possibilities for manned Mars missions are presented, covering topics such as space policy, space education and Mars exploration, economic issues, international cooperation, life support, biomedical factors, human factors, the Mars Rover Sample Return Mission, and possible unmanned precursor missions to Mars. Other topics include the scientific objectives for human exploration of Mars, mission strategies, possible transportation systems for manned Mars flight, advanced propulsion techniques, and the utilization of Mars resources. Additional subjects include the construction and maintenance of a Martian base, possible systems for mobility on the Martian surface, space power systems, and the use of the Space Station for a Mars mission.
Hultsch, Thomas; Kapp, Alexander; Spergel, Jonathan
2005-01-01
Atopic dermatitis (AD) is a chronic or chronically relapsing inflammatory skin condition that primarily affects children. Topical corticosteroids have been the mainstay of treatment since the late 1950s. While providing excellent short-term efficacy, topical corticosteroid usage is limited by potential adverse effects, including impairment of the function and viability of Langerhans cells/dendritic cells. The recently introduced topical calcineurin inhibitors pimecrolimus cream 1% (Elidel) and tacrolimus ointment 0.03 and 0.1% (Protopic) exhibit a more selective mechanism of action and do not affect Langerhans cells/dendritic cells. For the immune system of young children 'learning' to mount a balanced Th1/Th2 response, this selective effect has particular benefits. In clinical experience, topical calcineurin inhibitors have been shown to be a safe and effective alternative to topical corticosteroids in almost 7 million patients (>5 million on pimecrolimus; >1.7 million on tacrolimus). Topical pimecrolimus is primarily used in children with mild and moderate AD, whereas tacrolimus is used preferentially in more severe cases. None of the topical calcineurin inhibitors have been associated with systemic immunosuppression-related malignancies known to occur following long-term sustained systemic immunosuppression with oral immunosuppressants (e.g., tacrolimus, cyclosporine A, and corticosteroids) in transplant patients. Preclinical and clinical data suggest a greater skin selectivity and larger safety margin for topical pimecrolimus. (c) 2005 S. Karger AG, Basel
Discipline Based Instruction in Business Law
ERIC Educational Resources Information Center
Custin, Richard E.; Demas, John C.; Lampe, Marc; Custin, Colette L.
2013-01-01
Undergraduate business law courses typically utilize traditional textbooks organized by topic. Individual chapters, address the usual topics including contracts, torts, the court system and ethics. An innovative approach to facilitating a business law course involves segregating sections of the course into common business disciplines. Rather than…
NASA Space Engineering Research Center for Utilization of Local Planetary Resources
NASA Technical Reports Server (NTRS)
Ramohalli, Kumar; Lewis, John S.
1991-01-01
In the processing of propellants, volatiles, and metals subject area, the following topics are discussed: reduction of lunar regolith; reduction of carbon dioxide; and reduction of carbonaceous materials. Other areas addressed include: (1) production of structural and refractory materials; (2) resource discovery and characterization; (3) system automation and optimization; and (4) database development. The majority of these topics are discussed with respect to the development of lunar and mars bases. Some main topics of interest include: asteroid resources, lunar resources, mars resources, materials processing, construction materials, propellant production, oxygen production, and space-based oxygen production plants.
Performance of the upgraded Orroral laser ranging system
NASA Technical Reports Server (NTRS)
Luck, John M.
1993-01-01
The topics discussed include the following: upgrade arrangements, system prior to 1991, elements of the upgrade, laser performance, timing system performance, pass productivity, system precision, system accuracy, telescope pointing and future upgrades and extensions.
Data reduction expert assistant
NASA Technical Reports Server (NTRS)
Miller, Glenn E.; Johnston, Mark D.; Hanisch, Robert J.
1991-01-01
Viewgraphs on data reduction expert assistant are presented. Topics covered include: data analysis systems; philosophy of these systems; disadvantages; expert assistant; useful goals; and implementation considerations.
ERIC Educational Resources Information Center
Hirschbuhl, John J.
1992-01-01
Discusses the utilization of technology to assist the educational establishment deal with change. Topics addressed include multimedia metaphors such as graphical user interfaces; interactive videodisk systems; problems with current multimedia systems; a Multimedia Sampler developed at the University of North Carolina that includes applications…
Toward a Computational Model of Tutoring.
ERIC Educational Resources Information Center
Woolf, Beverly Park
1992-01-01
Discusses the integration of instructional science and computer science. Topics addressed include motivation for building knowledge-based systems; instructional design issues, including cognitive models, representing student intentions, and student models and error diagnosis; representing tutoring knowledge; building a tutoring system, including…
ERIC Educational Resources Information Center
Barber, Betsy; Ball, Rhonda
This project description is designed to show how graphing calculators and calculator-based laboratories (CBLs) can be used to explore topics in physics and health sciences. The activities address such topics as respiration, heart rate, and the circulatory system. Teaching notes and calculator instructions are included as are blackline masters. (MM)
ERIC Educational Resources Information Center
Gaines, Gale F., Comp.
2009-01-01
"The 2009 Legislative Briefing" is a topical summary of actions during the 2009 legislative sessions that affect education in the 16 SREB states. Topics include: state budgets and the economy; tax and revenue; teacher and faculty pay raises; retirement systems; issues affecting teachers and education leaders; health and safety;…
Development and validation of techniques for improving software dependability
NASA Technical Reports Server (NTRS)
Knight, John C.
1992-01-01
A collection of document abstracts are presented on the topic of improving software dependability through NASA grant NAG-1-1123. Specific topics include: modeling of error detection; software inspection; test cases; Magnetic Stereotaxis System safety specifications and fault trees; and injection of synthetic faults into software.
NASA's Solar System Exploration Program
NASA Technical Reports Server (NTRS)
Robinson, James
2005-01-01
A viewgraph presentation describing NASA's Solar System Exploration Program is shown. The topics include: 1) Solar System Exploration with Highlights and Status of Programs; 2) Technology Drivers and Plans; and 3) Summary
Conference on Space and Military Applications of Automation and Robotics
NASA Technical Reports Server (NTRS)
1988-01-01
Topics addressed include: robotics; deployment strategies; artificial intelligence; expert systems; sensors and image processing; robotic systems; guidance, navigation, and control; aerospace and missile system manufacturing; and telerobotics.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Barley, C.D.; Winn, C.B.
1997-12-31
This paper provides an overview of the emerging technology of remote, stand-alone electrical power systems featuring a renewable source (wind or photovoltaics [PV]) as well as a diesel generator, with or without an energy storage device. Other stand-alone power systems are discussed briefly, mainly to emphasize the domain of hybrid systems. The history of hybrid systems is reviewed, beginning with the first wind/diesel system in the late 1970s. Other topics include issues arising from the characteristics of diesel engine/generator sets; simple vs. complex systems; the various energy storage technologies that have been used or proposed; control strategies; modeling; optimization; andmore » some {open_quotes}nuts & bolts{close_quotes} details. The bibliography includes over 130 references which are cited throughout the topical discussions. It is concluded that the technical feasibility of hybrid systems has been demonstrated through many prototype installations, and that areas for further improvements include higher reliability and more economical energy storage devices. 139 refs., 7 figs., 1 tab.« less
2014-05-13
use of systemic corticosteroids, abnormal ophthalmic examination, and topographic evidence of keratoconus or warpage from contact 4 lenses...Systemic medications were permitted unless they were known to affect the cornea. Soft contact lenses were removed at least thirty days and hard contact ... contact lens was placed at conclusion of the treatment. All eyes received standard postoperative management during the first week including topical
NASA Technical Reports Server (NTRS)
1992-01-01
The NASA Marshall Space Flight Center Annual Report is presented. A description of research and development projects is included. Topics covered include: space science; space systems; transportation systems; astronomy and astrophysics; earth sciences; solar terrestrial physics; microgravity science; diagnostic and inspection system; information, electronic, and optical systems; materials and manufacturing; propulsion; and structures and dynamics.
ERIC Educational Resources Information Center
Tsai, Bor-sheng
1991-01-01
Examines the information communication process and proposes a fuzzy commonality model for improving communication systems. Topics discussed include components of an electronic information programing and processing system and the flow of the formation and transfer of information, including DOS (disk operating system) commands, computer programing…
Computer Sciences and Data Systems, volume 1
NASA Technical Reports Server (NTRS)
1987-01-01
Topics addressed include: software engineering; university grants; institutes; concurrent processing; sparse distributed memory; distributed operating systems; intelligent data management processes; expert system for image analysis; fault tolerant software; and architecture research.
NASA Technical Reports Server (NTRS)
Pell, Barney
2003-01-01
A viewgraph presentation on NASA's Discovery Systems Project is given. The topics of discussion include: 1) NASA's Computing Information and Communications Technology Program; 2) Discovery Systems Program; and 3) Ideas for Information Integration Using the Web.
Goddard Conference on Mass Storage Systems and Technologies, volume 2
NASA Technical Reports Server (NTRS)
Kobler, Ben (Editor); Hariharan, P. C. (Editor)
1993-01-01
Papers and viewgraphs from the conference are presented. Discussion topics include the IEEE Mass Storage System Reference Model, data archiving standards, high-performance storage devices, magnetic and magneto-optic storage systems, magnetic and optical recording technologies, high-performance helical scan recording systems, and low end helical scan tape drives. Additional discussion topics addressed the evolution of the identifiable unit for processing (file, granule, data set, or some similar object) as data ingestion rates increase dramatically, and the present state of the art in mass storage technology.
Understanding the Effects of Cytotoxic Chemotherapeutics on the Innate Immune System
2012-03-01
coursework has been completed. The remaining coursework, including three post-graduate courses and four “ Topics in Biology” courses have also been completed...Translational Cancer Research for Basic Scientists Workshop. The four “ Topics in Biology” courses taken are Evolution (2009), Statistics (2010...not taken, as Immunology was offered as a “ Topics in Biology” course at CSHL. The second course was not taken, as it has not been offered during 2010
"Modern Secondary Economics Textbooks and Ideological Bias."
ERIC Educational Resources Information Center
Romanish, Bruce A.
1983-01-01
An analysis of the way 10 high school economics textbooks treat the topics of other economic systems, labor, role of government, and environment showed that the texts present free enterprise principles to the exclusion of other ideas. Topics which, if included, would provide a more balanced overall treatment are discussed. (RM)
Mapping the Idea: A Notetaking System.
ERIC Educational Resources Information Center
Driskell, Jeanette
"Mapping" is a note-taking technique by which students use visual cues to isolate, emphasize, and group information meaningfully. Features of this technique include: organizing the note page laterally, so that general topics are on the left side and supportive information is on the right side; separating topics by horizontal lines;…
Operation Of The X-29A Digital Flight-Control System
NASA Technical Reports Server (NTRS)
Chacon, Vince; Mcbride, David
1990-01-01
Report reviews program of testing and evaluation of digital flight-control system for X-29A airplane, with emphasis on operation during tests. Topics include design of system, special electronic testing equipment designed to aid in daily operations, and aspects of testing, including detection of faults.
Give Customers What They Meant To Ask For--Designing Training Systems at Three Levels.
ERIC Educational Resources Information Center
Hybert, Peter R.
2001-01-01
Examines instructional systems design in light of training and performance technology. Topics include the nature of design; categories of stakeholders; three levels of instructional systems design, including Curriculum Architecture Design, instructional process design, and user interface/instructional activity design; and design goals. (LRW)
Fifth Annual Flight Mechanics/Estimation Theory Symposium
NASA Technical Reports Server (NTRS)
Teles, J. (Editor)
1980-01-01
Various aspects of astrodynamics are considered including orbit calculations and trajectory determination. Other topics dealing with remote sensing systems, satellite navigation, and attitude control are included.
NASA Astrophysics Data System (ADS)
Volná, M.; Látal, F.; Kubínek, R.; Richterek, L.
2014-01-01
Many topics which are closely related can be found in the national curriculum of the Czech Republic for physics and biology. One of them is the heart and the circulatory system in the human body. This topic was examined cross curriculum, a teaching module was created and the topic was chosen for our research. The task was to determine if the students of bachelor study are aware of connections between physics and biology within this topic and whether we can help them effectively to describe the corresponding physics phenomena in the human body connected, for example, with a heart attack or with the measurement of blood pressure. In this paper, the heart and the circulatory system are presented as suitable topics for an interdisciplinary teaching module which includes both theoretical and experimental parts. The module was evaluated by a group of first-year undergraduate students of physics at the Faculty of Science, Palacký University. The acquired knowledge was compared with another control group through a test. The highest efficiency of the module was evaluated on the basis of questions that covered the calculation problems.
Aquino, Marcella; Rosner, Greg
2018-05-15
Systemic contact dermatitis (SCD) traditionally refers to a skin condition where an individual who is cutaneously sensitized to an allergen will subsequently react to that same allergen or a cross reacting allergen via a different route. It occurs to allergens including metals, medications, and foods. The exact pathophysiology underlying this disease remains unknown, although it appears to be mediated by type 4 hypersensitivity reactions and possibly type 3 hypersensitivity reactions. The p-I concept (pharmacologic interaction with immunoreceptors) hypothesized that drugs are able to bind directly to a T cell receptor without first being presented by MHC (major histocompatibility complex) molecules and without prior metabolism, which would help explain why SCD can be seen on first exposure to medications. Nomenclature remains a challenge as SCD can be subcategorized using terms such as ACDS (allergic contact dermatitis syndrome) and its four clinical stages, Baboon syndrome, and SDRIFE (symmetrical drug-related intertriginous and flexural exanthema), which share many overlapping features. Food allergens may be responsible for uncontrolled or persistent symptoms in patients with contact dermatitis who do not respond to topical avoidance. With medications, symptoms may be induced by topical application versus systemic administration. Patch testing (PT) may be beneficial in diagnosing SCD caused by metals and many topical medications including corticosteroids, antimicrobials (ampicillin, bacitracin, erythromycin, neomycin, nystatin), NSAIDs (diclofenac, ibuprofen), anesthetics, and antihistamines (chlorphenamine, piperazine). Current treatment options include topical steroids and oral antihistamines for symptom relief and dietary avoidance to causative foods or metals.
Executive system software design and expert system implementation
NASA Technical Reports Server (NTRS)
Allen, Cheryl L.
1992-01-01
The topics are presented in viewgraph form and include: software requirements; design layout of the automated assembly system; menu display for automated composite command; expert system features; complete robot arm state diagram and logic; and expert system benefits.
Heterodyne systems and technology, part 1. [conferences
NASA Technical Reports Server (NTRS)
1980-01-01
Various aspects of optical heterodyning are considered. Topics covered heterodyning throughout the electromagnetic spectrum including detectors, local oscillators, tunable diode lasers, astronomical systems, and environmental sensors, with both active and passive systems represented.
Lunar surface vehicle model competition
NASA Technical Reports Server (NTRS)
1990-01-01
During Fall and Winter quarters, Georgia Tech's School of Mechanical Engineering students designed machines and devices related to Lunar Base construction tasks. These include joint projects with Textile Engineering students. Topics studied included lunar environment simulator via drop tower technology, lunar rated fasteners, lunar habitat shelter, design of a lunar surface trenching machine, lunar support system, lunar worksite illumination (daytime), lunar regolith bagging system, sunlight diffusing tent for lunar worksite, service apparatus for lunar launch vehicles, lunar communication/power cables and teleoperated deployment machine, lunar regolith bag collection and emplacement device, soil stabilization mat for lunar launch/landing site, lunar rated fastening systems for robotic implementation, lunar surface cable/conduit and automated deployment system, lunar regolith bagging system, and lunar rated fasteners and fastening systems. A special topics team of five Spring quarter students designed and constructed a remotely controlled crane implement for the SKITTER model.
Circulation Systems on Microcomputers.
ERIC Educational Resources Information Center
Carlson, Gary
1984-01-01
Reports on the use of microcomputers in comprehensive library circulation systems. Topics covered include system requirements (reliability, completeness); determining circulation system needs (saving money, improving service, modernization); limitations of microcomputers (capacity, kinds of data stored, number of stations or terminals); system…
Health information technology and the medical school curriculum.
Triola, Marc M; Friedman, Erica; Cimino, Christopher; Geyer, Enid M; Wiederhorn, Jo; Mainiero, Crystal
2010-12-01
Medical schools must teach core biomedical informatics competencies that address health information technology (HIT), including explaining electronic medical record systems and computerized provider order entry systems and their role in patient safety; describing the research uses and limitations of a clinical data warehouse; understanding the concepts and importance of information system interoperability; explaining the difference between biomedical informatics and HIT; and explaining the ways clinical information systems can fail. Barriers to including these topics in the curricula include lack of teachers; the perception that informatics competencies are not applicable during preclinical courses and there is no place in the clerkships to teach them; and the legal and policy issues that conflict with students' need to develop skills. However, curricular reform efforts are creating opportunities to teach these topics with new emphasis on patient safety, team-based medical practice, and evidence-based care. Overarching HIT competencies empower our students to be lifelong technology learners.
Optimizing topical therapies for treating psoriasis: a consensus conference.
Zeichner, Joshua A; Lebwohl, Mark G; Menter, Alan; Bagel, Jerry; Del Rosso, James Q; Elewski, Boni E; Feldman, Steven R; Kircik, Leon H; Koo, John; Gold, Linda Stein; Tanghetti, Emil
2010-09-01
In 2010, an expert committee of physicians and researchers in the field of dermatology working together as the Psoriasis Process of Care Consensus Panel developed consensus guidelines for the treatment of psoriasis. As much as possible, the guidelines were evidence based but also included the extensive clinical experience of the dermatologists. Psoriasis is a lifelong disease that requires long-term treatment and 80% of psoriasis patients have mild to moderate disease. Topical therapies play an important role in the treatment of psoriasis, especially in patients with mild to moderate disease. Patients usually start with monotherapy; however, in more severe cases (> 10% body surface area [BSA], severely impaired quality of life [QOL], or recalcitrant psoriatic lesions), multiple treatment modalities may be used as part of combination, sequential, or rotational therapeutic regimens. Main treatment options include topical steroids, systemic therapies, topical vitamin D treatments such as vitamin D3 ointment, retinoids, phototherapy, and biologic therapies. Other topical therapies include the following steroid-sparing agents: coal tar, anthralin, calcineurin inhibitors, keratolytics, and emollients. Therapeutic considerations also should focus on adherence, improving QOL, and promoting a good patient-physician relationship.
Expert Systems in Reference Services.
ERIC Educational Resources Information Center
Roysdon, Christine, Ed.; White, Howard D., Ed.
1989-01-01
Eleven articles introduce expert systems applications in library and information science, and present design and implementation issues of system development for reference services. Topics covered include knowledge based systems, prototype development, the use of artificial intelligence to remedy current system inadequacies, and an expert system to…
Large gap magnetic suspension system
NASA Technical Reports Server (NTRS)
Abdelsalam, Moustafa K.; Eyssa, Y. M.
1991-01-01
The design of a large gap magnetic suspension system is discussed. Some of the topics covered include: the system configuration, permanent magnet material, levitation magnet system, superconducting magnets, resistive magnets, superconducting levitation coils, resistive levitation coils, levitation magnet system, and the nitrogen cooled magnet system.
Shapiro, Stanley; Heremans, Annie; Mays, David A; Martin, Amber L; Hernandez-Medina, Marisol; Lanes, Stephan
2011-12-01
Topical retinoids have been in clinical use for the treatment of chronic skin conditions, including acne, photodamage, and psoriasis, for 30 years. A systematic literature review was conducted to assess the incidence of noncutaneous adverse events (AE) among patients treated with topical retinoids with a focus on topical tretinoin studies reported before the Veterans Affairs Topical Tretinoin Chemoprevention trial. Electronic literature searches were conducted in Embase and MEDLINE for literature reporting development of nonteratogenic, noncutaneous AE among patients treated with topical retinoids published through September 2008. The search yielded 2778 citations, of which 20 studies met inclusion criteria. Tretinoin was used in 14 of the studies. Other retinoids assessed included isotretinoin, adapalene, alitretinoin, and tazarotene. Within patients receiving topical tretinoin, 27.9% reported the occurrence of at least one noncutaneous AE. The majority of noncutaneous AE were transient and judged not to be related to tretinoin treatment. The conclusions of this study apply largely to tretinoin compared with other topical retinoids. Many of the included trials were designed to evaluate the efficacy of topical treatment and reporting of safety events concentrated on incidence of localized AE, rather than systemic or noncutaneous events. We found no clear evidence of a relationship between the use of topical tretinoin and the development of noncutaneous AE before a recent report of excess mortality in a clinical trial. The majority of noncutaneous AE reported by patients receiving topical retinoids consisted of nonsevere, nonspecific symptoms that were judged not to be related to treatment. Copyright © 2010 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.
Dressler, Corinna; Rosumeck, Stefanie; Sunderkötter, Cord; Werner, Ricardo Niklas; Nast, Alexander
2016-11-14
Scabies is a contagious infestation transmitted by skin-to-skin contact and sometimes by contact with contaminated material. The scabies mite burrows into the skin, producing a papular rash and severe itch at typical sites of predilection. We systematically reviewed the literature to compare the efficacy of various anti-scabies agents, including a calculation of relative risks and confidence intervals. A literature search yielded 596 initial hits; after screening in accor-dance with the defined inclusion and exclusion criteria, 16 studies were selected for this review. Among topical treatments for scabies, permethrin was equally effective or more effective than crotamiton or benzyl benzoate. In a comparison of topical versus systemic treatment, topical permethrin and systemic ivermectin did not differ substantially in efficacy (7 comparative studies revealed no difference; one revealed a difference in favor of permethrin). Comparative trials of topical benzyl benzoate versus systemic ivermectin yielded inconsistent findings. Single and double administrations of ivermectin were similarly effective. In trials involving entire populations with a high prevalence of scabies, systemic ivermectin was found to be superior to topical permethrin. There are hardly any differences in efficacy between the available treatments for scabies. Single administrations of permethrin 5%, crotamiton 10%, and systemic ivermectin are all comparably effective. There are differences in the frequeny and ease of application as well as when eradicating scabies in populations with a high prevalence.
Man-systems distributed system for Space Station Freedom
NASA Technical Reports Server (NTRS)
Lewis, J. L.
1990-01-01
Viewgraphs on man-systems distributed system for Space Station Freedom are presented. Topics addressed include: description of man-systems (definition, requirements, scope, subsystems, and topologies); implementation (approach, tools); man-systems interfaces (system to element and system to system); prime/supporting development relationship; selected accomplishments; and technical challenges.
Industrial and Systems Engineering Applications in NASA
NASA Technical Reports Server (NTRS)
Shivers, Charles H.
2006-01-01
A viewgraph presentation on the many applications of Industrial and Systems Engineering used for safe NASA missions is shown. The topics include: 1) NASA Information; 2) Industrial Engineering; 3) Systems Engineering; and 4) Major NASA Programs.
Joint Standing Committee on Education: Update on Higher Education Personnel Study
ERIC Educational Resources Information Center
West Virginia Higher Education Policy Commission, 2006
2006-01-01
The following topics are included in this update: (1) Comparison of West Virginia classification and compensation systems to those of the University of Michigan, the University system of Maryland, and the University of North Carolina; (2) Classification and Compensation System Training, including an agenda and summary of a two-day seminar devoted…
Sixth New Zealand Computer Conference (Auckland 78). Volume I, Papers.
ERIC Educational Resources Information Center
New Zealand Computer Society, Auckland.
This collection of conference presentations includes 23 papers on a variety of topics pertaining to the use of computer in New Zealand. Among the topics discussed are computer science techniques in a commercial data processing situation, data processing personnel and their careers, the communication aspects of an airline system, implementation of…
Life Science. Nevada Competency-Based Adult High School Diploma Project.
ERIC Educational Resources Information Center
Nevada Univ., Las Vegas. Coll. of Education.
This document is one of ten curriculum guides developed by the Nevada Competency-Based Adult High School Diploma (CBAHSD) Project. This curriculum guide on life science is divided into twelve topics. The topics included are Life Process, Cells, Levels of Organization, Organ Systems, Food and Oxygen-Photosynthesis, Cycles, Energy, Resources, Cell…
Patterns of landscape dynamics and land use systems in the Southeastern Coastal Plain, USA
USDA-ARS?s Scientific Manuscript database
A variety of topics focused on research accomplished in the southeastern US were presented at this talk given on January 28, 2016, at the Brown Bag colloquium hosted by the University of Georgia Department of Geography. Topics covered included: a study analyzing road network and landscape change in ...
The Telecommunications and Data Acquisition Report
NASA Technical Reports Server (NTRS)
Posner, E. C. (Editor)
1988-01-01
Deep Space Network and Systems topics addressed include: tracking and ground-base navigation; communications, spacecraft-ground; station control and system technology; capabilities for existing projects; and network upgrading and sustaining.
Integrated Flywheel Technology, 1983
NASA Technical Reports Server (NTRS)
Keckler, C. R. (Editor); Rodriguez, G. E. (Editor); Groom, N. J. (Editor)
1983-01-01
Topics of discussion included: technology assessment of the integrated flywheel systems, potential of system concepts, identification of critical areas needing development and, to scope and define an appropriate program for coordinated activity.
Bioelectronic Learning: The Effects of Electronic Media on a Developing Brain.
ERIC Educational Resources Information Center
Sylwester, Robert
1997-01-01
Considers the effects of electronic media on the developing brains of children. Topics include the attentional demands of electronic media; commercial sponsorship; brain development, including memory systems and response systems; and what a developing mind can bring to the electronic media. (LRW)
Research Methods Tutor: evaluation of a dialogue-based tutoring system in the classroom.
Arnott, Elizabeth; Hastings, Peter; Allbritton, David
2008-08-01
Research Methods Tutor (RMT) is a dialogue-based intelligent tutoring system for use in conjunction with undergraduate psychology research methods courses. RMT includes five topics that correspond to the curriculum of introductory research methods courses: ethics, variables, reliability, validity, and experimental design. We evaluated the effectiveness of the RMT system in the classroom using a nonequivalent control group design. Students in three classes (n = 83) used RMT, and students in two classes (n = 53) did not use RMT. Results indicated that the use of RMT yieldedstrong learning gains of 0.75 standard deviations above classroom instruction alone. Further, the dialogue-based tutoring condition of the system resulted in higher gains than did the textbook-style condition (CAI version) of the system. Future directions for RMT include the addition of new topics and tutoring elements.
Controlled Ecological Life Support Systems: CELSS '89 Workshop
NASA Technical Reports Server (NTRS)
Macelroy, Robert D. (Editor)
1990-01-01
Topics discussed at NASA's Controlled Ecological Life Support Systems (CELSS) workshop concerned the production of edible biomass. Specific areas of interest ranged from the efficiency of plant growth, to the conversion of inedible plant material to edible food, to the use of plant culture techniques. Models of plant growth and whole CELSS systems are included. The use of algae to supplement and improve dietary requirements is addressed. Flight experimentation is covered in topics ranging from a Salad Machine for use on the Space Station Freedom to conceptual designs for a lunar base CELSS.
Electronic Document Supply Systems.
ERIC Educational Resources Information Center
Cawkell, A. E.
1991-01-01
Describes electronic document delivery systems used by libraries and document image processing systems used for business purposes. Topics discussed include technical specifications; analogue read-only laser videodiscs; compact discs and CD-ROM; WORM; facsimile; ADONIS (Article Delivery over Network Information System); DOCDEL; and systems at the…
USSR Space Life Sciences Digest. Index to issues 15-20
NASA Technical Reports Server (NTRS)
Hooke, Lydia Razran (Editor)
1989-01-01
This bibliography provides an index to issues 15 through 20 of the USSR Space Life Sciences Digest. There are two sections. The first section lists bibliographic citations of abstracts in these issues, grouped by topic area categories. The second section provides a key word index for the same abstracts. The topic categories include exobiology, space medicine and psychology, human performance and man-machine systems, various life/body systems, human behavior and adaptation, biospherics, and others.
USSR Space Life Sciences Digest. Index to issues 21-25
NASA Technical Reports Server (NTRS)
Hooke, Lydia Razran (Editor)
1990-01-01
This bibliography provides an index to issues 21 through 25 of the USSR Space Life Sciences Digest. There are two sections. The first section lists bibliographic citations of abstracts in these issues, grouped by topic area categories. The second section provides a key word index for the same abstracts. The topic categories include exobiology, space medicine and psychology, human performance and man-machine systems, various life/body systems, human behavior and adaptation, biospherics, and others.
USSR Space Life Sciences Digest. Index to issues 26-29
NASA Technical Reports Server (NTRS)
Stone, Lydia Razran (Editor)
1991-01-01
This bibliography provides an index to issues 26 through 29 of the USSR Space Life Sciences Digest. There are two sections. The first section lists bibliographic citations of abstracts in these issues, grouped by topic area categories. The second section provides a key word index for the same abstracts. The topic categories include exobiology, space medicine and psychology, human performance and man-machine systems, various life/body systems, human behavior and adaptation, biospherics, and others.
Beyond Our Boundaries: Research and Technology
NASA Technical Reports Server (NTRS)
1996-01-01
Topics considered include: Propulsion and Fluid Management; Structures and Dynamics; Materials and Manufacturing Processes; Sensor Technology; Software Technology; Optical Systems; Microgravity Science; Earth System Science; Astrophysics; Solar Physics; and Technology Transfer.
Corneal anesthetic abuse and Candida keratitis.
Chern, K C; Meisler, D M; Wilhelmus, K R; Jones, D B; Stern, G A; Lowder, C Y
1996-01-01
Topical corneal anesthetic abuse is a self-inflicted injury, causing profound corneal morbidity. Superimposed infection is an important complicating factor. The authors report four patients with confirmed topical anesthetic abuse of the cornea, in whom Candida keratitis developed. A retrospective review of the medical records of four patients with confirmed topical corneal anesthetic abuse and fungal keratitis. A 21-year-old woman, two 28-year-old women, and a 35-year-old man were included in the study. All these patients sustained a corneal injury, prompting the chronic use of topical anesthetics (0.5% proparacaine hydrochloride in 3 patients, and 0.5% tetracaine hydrochloride and 0.4% benoxinate hydrochloride in the other). Corneal findings included epithelial defects in all patients, focal infiltrate in one patient, and ring-shaped stromal infiltrate in three patients. Topical anesthetic was discontinued, all patients initially were treated empirically with antibacterial agents, and three patients received topical corticosteroids. Subsequent corneal cultures grew Candida spp, Candida albicans specifically in three patients, and local and systemic antifungal therapy was started. Corneas in two patients re-epithelialized; a conjunctival flap was performed on another patient with a descemetocele; and the remaining patient was lost to follow-up, although repeat fungal cultures yielded no growth. Corneal superinfection with Candida may occur during topical anesthetic abuse. Therapy includes discontinuation of the anesthetic and institution of antifungal therapy.
Designing a Digital Instructional Management System To Optimize Early Education.
ERIC Educational Resources Information Center
Mooij, Ton
2002-01-01
Discusses digital instructional management systems (DIMSs) and describes a pilot study conducted in two Dutch kindergartens with a prototype DIMS that included individualization and optimization, that is matching curriculum with learner characteristics. Topics include learning processes for children at risk; and future plans. (LRW)
Payment Services for Global Online Systems Including Internet.
ERIC Educational Resources Information Center
Seebeck, Bill; And Others
1995-01-01
A panel of four conference presenters address issues related to paying for services provided through online systems. Discussion includes the following topics: metering devices; electronic/digital cash; working within existing banking/credit card structures; provision of payment mechanisms in countries without extensive credit card usage; and…
Data Compression in Full-Text Retrieval Systems.
ERIC Educational Resources Information Center
Bell, Timothy C.; And Others
1993-01-01
Describes compression methods for components of full-text systems such as text databases on CD-ROM. Topics discussed include storage media; structures for full-text retrieval, including indexes, inverted files, and bitmaps; compression tools; memory requirements during retrieval; and ranking and information retrieval. (Contains 53 references.)…
Looking at Earth from Space: Teacher's Guide with Activities for Earth and Space Science
NASA Technical Reports Server (NTRS)
Steele, Colleen (Editor); Steele, Colleen; Ryan, William F.
1995-01-01
The Maryland Pilot Earth Science and Technology Education Network (MAPS-NET) project was sponsored by the National Aeronautics and Space Administration (NASA) to enrich teacher preparation and classroom learning in the area of Earth system science. This publication includes a teacher's guide that replicates material taught during a graduate-level course of the project and activities developed by the teachers. The publication was developed to provide teachers with a comprehensive approach to using satellite imagery to enhance science education. The teacher's guide is divided into topical chapters and enables teachers to expand their knowledge of the atmosphere, common weather patterns, and remote sensing. Topics include: weather systems and satellite imagery including mid-latitude weather systems; wave motion and the general circulation; cyclonic disturbances and baroclinic instability; clouds; additional common weather patterns; satellite images and the internet; environmental satellites; orbits; and ground station set-up. Activities are listed by suggested grade level and include the following topics: using weather symbols; forecasting the weather; cloud families and identification; classification of cloud types through infrared Automatic Picture Transmission (APT) imagery; comparison of visible and infrared imagery; cold fronts; to ski or not to ski (imagery as a decision making tool), infrared and visible satellite images; thunderstorms; looping satellite images; hurricanes; intertropical convergence zone; and using weather satellite images to enhance a study of the Chesapeake Bay. A list of resources is also included.
AstRoMap European Astrobiology Roadmap
Horneck, Gerda; Westall, Frances; Grenfell, John Lee; Martin, William F.; Gomez, Felipe; Leuko, Stefan; Lee, Natuschka; Onofri, Silvano; Tsiganis, Kleomenis; Saladino, Raffaele; Pilat-Lohinger, Elke; Palomba, Ernesto; Harrison, Jesse; Rull, Fernando; Muller, Christian; Strazzulla, Giovanni; Brucato, John R.; Rettberg, Petra; Capria, Maria Teresa
2016-01-01
Abstract The European AstRoMap project (supported by the European Commission Seventh Framework Programme) surveyed the state of the art of astrobiology in Europe and beyond and produced the first European roadmap for astrobiology research. In the context of this roadmap, astrobiology is understood as the study of the origin, evolution, and distribution of life in the context of cosmic evolution; this includes habitability in the Solar System and beyond. The AstRoMap Roadmap identifies five research topics, specifies several key scientific objectives for each topic, and suggests ways to achieve all the objectives. The five AstRoMap Research Topics are • Research Topic 1: Origin and Evolution of Planetary Systems• Research Topic 2: Origins of Organic Compounds in Space• Research Topic 3: Rock-Water-Carbon Interactions, Organic Synthesis on Earth, and Steps to Life• Research Topic 4: Life and Habitability• Research Topic 5: Biosignatures as Facilitating Life Detection It is strongly recommended that steps be taken towards the definition and implementation of a European Astrobiology Platform (or Institute) to streamline and optimize the scientific return by using a coordinated infrastructure and funding system. Key Words: Astrobiology roadmap—Europe—Origin and evolution of life—Habitability—Life detection—Life in extreme environments. Astrobiology 16, 201–243. PMID:27003862
NASA Technical Reports Server (NTRS)
Vette, J. I. (Editor); Runcorn, S. K. (Editor); Gruen, E. (Editor); Mcdonnell, J. A. M.
1982-01-01
Topics discussed include the magnetic history of the early solar system, impact processes in solid bodies (e.g., meteoroids and asteroids), and topics related to cometary missions. The section devoted to cometary missions lays particular stress on missions to Comet Halley; attention is given to such aspects of these missions as the investigation of hypervelocity impact on the Giotto Halley mission dust shield, the detection of energetic cometary and solar particles by the EPONA instrument on the Giotto mission, the dust hazard near Comet Halley in regard to the Vega project, and cometary ephemerides for spacecraft flyby missions.
Applied Information Systems Research Program Workshop
NASA Technical Reports Server (NTRS)
Bredekamp, Joe
1991-01-01
Viewgraphs on Applied Information Systems Research Program Workshop are presented. Topics covered include: the Earth Observing System Data and Information System; the planetary data system; Astrophysics Data System project review; OAET Computer Science and Data Systems Programs; the Center of Excellence in Space Data and Information Sciences; and CASIS background.
ERIC Educational Resources Information Center
Nogami, Glenda Y., Ed.; And Others
The 21 summaries of research programs, funded by the United States Army Research Institute (ARI) for the Behavioral and Social Sciences which are presented are grouped in five broad topic areas: computer-based systems; information processing; learning, memory and transfer; human relations; and related issues and trends. Papers presented include:…
The Next Great Ship: NASA's Space Launch System
NASA Technical Reports Server (NTRS)
May, Todd A.
2013-01-01
Topics covered include: Most Capable U.S. Launch Vehicle; Liquid engines Progress; Boosters Progress; Stages and Avionics Progress; Systems Engineering and Integration Progress; Spacecraft and Payload Integration Progress; Advanced Development Progress.
Technology for Space Station Evolution: the Data Management System
NASA Technical Reports Server (NTRS)
Abbott, L.
1990-01-01
Viewgraphs on the data management system (DMS) for the space station evolution are presented. Topics covered include DMS architecture and implementation approach; and an overview of the runtime object database.
Next generation system modeling of NTR systems
NASA Technical Reports Server (NTRS)
Buksa, John J.; Rider, William J.
1993-01-01
The topics are presented in viewgraph form and include the following: nuclear thermal rocket (NTR) modeling challenges; current approaches; shortcomings of current analysis method; future needs; and present steps to these goals.
Research and technology: Fiscal year 1984 report
NASA Technical Reports Server (NTRS)
1985-01-01
Topics covered include extraterrestrial physics, high energy astrophysics, astronomy, solar physics, atmospheres, oceans, terrestrial physics, space technology, sensors, techniques, user space data systems, space communications and navigation, and system and software engineering.
Topical treatment of psoriasis.
Laws, Philip M; Young, Helen S
2010-08-01
The majority of patients with psoriasis can be safely and effectively treated with topical therapy alone, either under the supervision of a family physician or dermatologist. For those requiring systemic agents, topical therapies can provide additional benefit. Optimal use of topical therapy requires an awareness of the range and efficacy of all products. The review covers the efficacy and role of topical therapies including emollients, corticosteroids, vitamin D analogs, calcineurin inhibitors, dithranol, coal tar, retinoids, keratolyics and combination therapy. The report was prepared following a PubMed and Embase literature search up to April 2010. The paper provides a broad review of the relevant topical therapeutic options available in routine clinical practice for the management of psoriasis and a recommendation for selection of treatment. Topical therapies used appropriately provide a safe and effective option for the management of psoriasis. An awareness of the available products and their efficacy is key to treatment selection and patient satisfaction.
Automatic Management of Parallel and Distributed System Resources
NASA Technical Reports Server (NTRS)
Yan, Jerry; Ngai, Tin Fook; Lundstrom, Stephen F.
1990-01-01
Viewgraphs on automatic management of parallel and distributed system resources are presented. Topics covered include: parallel applications; intelligent management of multiprocessing systems; performance evaluation of parallel architecture; dynamic concurrent programs; compiler-directed system approach; lattice gaseous cellular automata; and sparse matrix Cholesky factorization.
Accounting for User Diversity in Configuring Online Systems.
ERIC Educational Resources Information Center
Woolliams, Peter; Gee, David
1992-01-01
Discusses cultural diversity in human-computer interactions and in the design of online systems. Topics addressed include cognitive psychology; North American and European ethnocentricity; online systems and their organizational setting; models for organization culture; corporate culture; international systems and country-specific cultures; and…
Instructional Systems. The Educational Technology Reviews Series. Number Eight.
ERIC Educational Resources Information Center
Educational Technology Publications, Englewood Cliffs, NJ.
Composed of articles which appeared recently in "Educational Technology" magazine, this volume in the review series considers instructional systems. Topics covered include systems models for instructional design and management, the design of simulation systems, informal and vocational education, individualized instruction, operational learning…
Knowledge-Based Information Retrieval.
ERIC Educational Resources Information Center
Ford, Nigel
1991-01-01
Discussion of information retrieval focuses on theoretical and empirical advances in knowledge-based information retrieval. Topics discussed include the use of natural language for queries; the use of expert systems; intelligent tutoring systems; user modeling; the need for evaluation of system effectiveness; and examples of systems, including…
NASA Technical Reports Server (NTRS)
Freeman, Anthony; Dubois, Pascale; Leberl, Franz; Norikane, L.; Way, Jobea
1991-01-01
Viewgraphs on Geographic Information System for fusion and analysis of high-resolution remote sensing and ground truth data are presented. Topics covered include: scientific objectives; schedule; and Geographic Information System.
Expert Systems: Tutors, Tools, and Tutees.
ERIC Educational Resources Information Center
Lippert, Renate C.
1989-01-01
Discusses the current status, research, and practical implications of artificial intelligence and expert systems in education. Topics discussed include computer-assisted instruction; intelligent computer-assisted instruction; intelligent tutoring systems; instructional strategies involving the creation of knowledge bases; decision aids;…
Get Involved in Planetary Discoveries through New Worlds, New Discoveries
NASA Astrophysics Data System (ADS)
Shupla, Christine; Shipp, S. S.; Halligan, E.; Dalton, H.; Boonstra, D.; Buxner, S.; SMD Planetary Forum, NASA
2013-01-01
"New Worlds, New Discoveries" is a synthesis of NASA’s 50-year exploration history which provides an integrated picture of our new understanding of our solar system. As NASA spacecraft head to and arrive at key locations in our solar system, "New Worlds, New Discoveries" provides an integrated picture of our new understanding of the solar system to educators and the general public! The site combines the amazing discoveries of past NASA planetary missions with the most recent findings of ongoing missions, and connects them to the related planetary science topics. "New Worlds, New Discoveries," which includes the "Year of the Solar System" and the ongoing celebration of the "50 Years of Exploration," includes 20 topics that share thematic solar system educational resources and activities, tied to the national science standards. This online site and ongoing event offers numerous opportunities for the science community - including researchers and education and public outreach professionals - to raise awareness, build excitement, and make connections with educators, students, and the public about planetary science. Visitors to the site will find valuable hands-on science activities, resources and educational materials, as well as the latest news, to engage audiences in planetary science topics and their related mission discoveries. The topics are tied to the big questions of planetary science: how did the Sun’s family of planets and bodies originate and how have they evolved? How did life begin and evolve on Earth, and has it evolved elsewhere in our solar system? Scientists and educators are encouraged to get involved either directly or by sharing "New Worlds, New Discoveries" and its resources with educators, by conducting presentations and events, sharing their resources and events to add to the site, and adding their own public events to the site’s event calendar! Visit
Activated Sludge. Student Manual. Biological Treatment Process Control.
ERIC Educational Resources Information Center
Boe, Owen K.; Klopping, Paul H.
This student manual contains the textual material for a seven-lesson unit on activated sludge. Topic areas addressed in the lessons include: (1) activated sludge concepts and components (including aeration tanks, aeration systems, clarifiers, and sludge pumping systems); (2) activated sludge variations and modes; (3) biological nature of activated…
Supplementary and Enrichment Series: Mathematical Systems. Teachers' Commentary. SP-20.
ERIC Educational Resources Information Center
Syer, Henry W., Ed.
This is one in a series of manuals for teachers using SMSG high school supplementary materials. The pamphlet includes commentaries on the sections of the student's booklet, answers to the exercises, and sample test questions. Topics covered include addition, multiplication, operations, closure, identity element, mathematical systems, mathematical…
Fourth Annual Workshop on Space Operations Applications and Research (SOAR 90)
NASA Technical Reports Server (NTRS)
Savely, Robert T. (Editor)
1991-01-01
The papers from the symposium are presented. Emphasis is placed on human factors engineering and space environment interactions. The technical areas covered in the human factors section include: satellite monitoring and control, man-computer interfaces, expert systems, AI/robotics interfaces, crew system dynamics, and display devices. The space environment interactions section presents the following topics: space plasma interaction, spacecraft contamination, space debris, and atomic oxygen interaction with materials. Some of the above topics are discussed in relation to the space station and space shuttle.
1993-01-01
and toughness and strength will be evaluated by pressurized ring tensile tests. MUDAWAR THERMAL SYSTEM, INC. Topic#: 92-136 ID#: 92N40-240 1217...ARMY Topic#: 92-056 MTL SYSTEMS, INC. AF TopicS: 93-051 MIMS TECHNOLOGY DEVELOPMENT COMPANY AF Topic#: 93-111 AF Topic#: 93-011 MUDAWAR THERMAL SYSTEM...156 MUDAWAR THERMAL SYSTEM, INC. ANALYTICAL SERVICES & MATERIALS, INC. NAVY Topic#: 92-137 NAVY Topic#: 92-157 MOUNTAIN OPTECH, INC. DATAMAT SYSTEMS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dobson, Ian; Hiskens, Ian; Linderoth, Jeffrey
Building on models of electrical power systems, and on powerful mathematical techniques including optimization, model predictive control, and simluation, this project investigated important issues related to the stable operation of power grids. A topic of particular focus was cascading failures of the power grid: simulation, quantification, mitigation, and control. We also analyzed the vulnerability of networks to component failures, and the design of networks that are responsive to and robust to such failures. Numerous other related topics were investigated, including energy hubs and cascading stall of induction machines
Sanz, Roser; Calpena, Ana C; Mallandrich, Mireia; Clares, Beatriz
2015-01-01
Topical administration is an appealing method for drug delivery due to its non-invasiveness, self-controlled application, avoidance of first-pass metabolism in the liver and reduction of systemic side effects compared to other conventional routes such as oral and parenteral. However, topical administration must overcome the permeable barriers that skin and mucosa represent for the drug to achieve its desired therapeutic effect. Penetration of drugs through human skin is mainly impaired by the stratum corneum- the uppermost keratinized skin layer. In contrast, the stratified squamous epithelium (a nonkeratinized tissue) represents the major physical barrier for transbuccal drug administration in humans. Different technologies have been studied to enhance the bioavailability or local effects of drugs administered through skin and buccal mucosa. Those technologies involve the use of physical or chemical enhancers and new dosage forms such as vesicles, cyclodextrins, nanoparticles and other complex systems. Combinations of these technologies may further increase drug delivery in some cases. As analgesia is one of the main therapeutic effects sought through topical administration, this paper focuses on the review of drug delivery systems to improve the topical and transdermal/transbuccal drug delivery of substances with known analgesic action. A discussion of their possibilities and limitations is also included.
Friedman, Avner; Lachowicz, Mirosław; Ledzewicz, Urszula; Piotrowska, Monika Joanna; Szymanska, Zuzanna
2017-02-01
This volume was inspired by the topics presented at the international conference "Micro and Macro Systems in Life Sciences" which was held on Jun 8-12, 2015 in Będlewo, Poland. System biology is an approach which tries to understand how micro systems, at the molecular and cellular levels, affect macro systems such as organs, tissue and populations. Thus it is not surprising that a major theme of this volume evolves around cancer and its treatment. Articles on this topic include models for tumor induced angiogenesis, without and with delays, metastatic niche of the bone marrow, drug resistance and metronomic chemotherapy, and virotherapy of glioma. Methods range from dynamical systems to optimal control. Another well represented topic of this volume is mathematical modeling in epidemiology. Mathematical approaches to modeling and control of more specific diseases like malaria, Ebola or human papillomavirus are discussed as well as a more general approaches to the SEIR, and even more general class of models in epidemiology, by using the tools of optimal control and optimization. The volume also brings up challenges in mathematical modeling of other diseases such as tuberculosis. Partial differential equations combined with numerical approaches are becoming important tools in modeling not only tumor growth and treatment, but also other diseases, such as fibrosis of the liver, and atherosclerosis and its associated blood flow dynamics, and our volume presents a state of the art approach on these topics. Understanding mathematics behind the cell motion, appearance of the special patterns in various cell populations, and age structured mutations are among topics addressed inour volume. A spatio-temporal models of synthetic genetic oscillators brings the analysis to the gene level which is the focus of much of current biological research. Mathematics can help biologists to explain the collective behavior of bacterial, a topic that is also presented here. Finally some more across the discipline topics are being addresses, which can appear as a challenge in studying problems in systems biology on all, macro, meso and micro levels. They include numerical approaches to stochastic wave equation arising in modeling Brownian motion, discrete velocity models, many particle approximations as well as very important aspect on the connection between discrete measurement and the construction of the models for various phenomena, particularly the one involving delays. With the variety of biological topics and their mathematical approaches we very much hope that the reader of the Mathematical Biosciences and Engineering will find this volume interesting and inspirational for their own research.
NASA Tech Briefs, February 1988. Volume 12, No. 2
NASA Technical Reports Server (NTRS)
1988-01-01
Topics covered include: New Product Ideas; NASA TU Services; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Systems; and Life Sciences.
Bibliography: Artificial Intelligence.
ERIC Educational Resources Information Center
Smith, Richard L.
1986-01-01
Annotates reference material on artificial intelligence, mostly at an introductory level, with applications to education and learning. Topics include: (1) programing languages; (2) expert systems; (3) language instruction; (4) tutoring systems; and (5) problem solving and reasoning. (JM)
Aeronautics Technology Possibilities for 2000: Report of a Workshop
NASA Technical Reports Server (NTRS)
1984-01-01
Topics discussed include: Aerodynamics; Propulsion; Structural Analysis and Design Technology; Materials for Structural Members, Propulsion Systems, and Subsystems; Guidance, Navigation, and Control; Computer and Information Technology; Human Factors Engineering; Systems Integration.
ERIC Educational Resources Information Center
Jacob, Willis H.; Carter, Robert, III
This document features review questions, crossword puzzles, and word search puzzles on human anatomy. Topics include: (1) Anatomical Terminology; (2) The Skeletal System and Joints; (3) The Muscular System; (4) The Nervous System; (5) The Eye and Ear; (6) The Circulatory System and Blood; (7) The Respiratory System; (8) The Urinary System; (9) The…
Topical agents for oral cancer chemoprevention: A systematic review of the literature.
Chau, Lucy; Jabara, Justin T; Lai, Wanda; Svider, Peter F; Warner, Blake M; Lin, Ho-Sheng; Raza, S Naweed; Fribley, Andrew M
2017-04-01
We review the use of topical chemoprevention agents in patients with oral potentially malignant disorders (PMD). A systematic review of studies on topical chemoprevention agents for oral PMD from 1946 to November 2016 was conducted using the MEDLINE database, Embase, and Cochrane Library. Data were extracted and analyzed from selected studies including study type, sample size, demographics, treatment length, response rate, follow-up time, adverse effects, and recurrence. Of 108 studies, twenty-four, representing 679 cases met the inclusion criteria. The clinical lesions evaluated included oral leukoplakia, erythroplakia (OEL), verrucous hyperplasia (OVH), oral lichen planus, larynx squamous cell carcinoma, and oral squamous cell carcinoma (OSCC). The mean complete response rate for topical retinoid therapy was 32%. The mean complete response rate for 1% bleomycin therapy and 0.5% bleomycin was 40.2% and 25%, respectively. The complete response rate of OVH, OEL, and OSCC to photodynamic therapy ranged from 66.7% to 100%. There are a paucity of data examining topical treatment of oral PMDs. However, the use of topical agents among patients with oral lesions may be a viable complement or even alternative to traditional surgery, radiation, or systemic chemotherapy, with the advantage of reducing systemic side effects and sparing important anatomic structures. This study of 679 cases represents the largest pooled sample size to date, and the preliminary studies in this systematic review provide support for further inquiry. Copyright © 2017 Elsevier Ltd. All rights reserved.
Automobile Course. Progress Record and Theory Outline.
ERIC Educational Resources Information Center
Connecticut State Dept. of Education, Hartford. Div. of Vocational-Technical Schools.
This combination progress record and course outline is designed for use by individuals teaching a course in automobile repair. Included among the topics addressed in the course are the following: shop safety, engines, fuel and exhaust systems, electrical systems, crankcase lubrication systems, cooling systems, power transmission systems, steering…
Columbia's first flight shakes down space transportation system
NASA Technical Reports Server (NTRS)
Garrett, D.; Young, D.; White, T.
1981-01-01
The first space shuttle mission is described. Topics include launch preparations, flight profile, trajectory, and landing operations. The spaceflight tracking and data network is discussed and the photography and television schedules are included.
An Air Force Guide to the System Specification.
1981-01-01
basis for sound management plans and decisions to initiate system full-scale development. Related topics include: current problems and questions...such current documents as AFR 800-2 and AFR 57-1. Key elements of coverage include the following: a. Levels of system engineering studies are...equipment and computer program elements of a system are acquired most directly acainst lower-level (configuration item) specifications. b. Current
Systemic and Topical Use of Tranexamic Acid in Spinal Surgery: A Systematic Review
Winter, Sebastian F.; Santaguida, Carlo; Wong, Jean; Fehlings, Michael G.
2015-01-01
Study Design Combination of narrative and systematic literature reviews. Objectives Massive perioperative blood loss in complex spinal surgery often requires blood transfusions and can negatively affect patient outcome. Systemic use of the antifibrinolytic agent tranexamic acid (TXA) has become widely used in the management of surgical bleeding. We review the clinical evidence for the use of intravenous TXA as a hemostatic agent in spinal surgery and discuss the emerging role for its complementary use as a topical agent to reduce perioperative blood loss from the surgical site. Through a systematic review of published and ongoing investigations on topical TXA for spinal surgery, we wish to make spine practitioners aware of this option and to suggest opportunities for further investigation in the field. Methods A narrative review of systemic TXA in spinal surgery and topical TXA in surgery was conducted. Furthermore, a systematic search (using PRISMA guidelines) of PubMed (MEDLINE), EMBASE, and Cochrane CENTRAL databases as well as World Health Organization International Clinical Trials Registry Platform, ClinicalTrials.gov (National Institutes of Health), and International Standard Randomized Controlled Trial Number registries was conducted to identify both published literature and ongoing clinical trials on topical TXA in spinal surgery. Results Of 1,631 preliminary search results, 2 published studies were included in the systematic review. Out of 285 ongoing clinical trials matching the search criteria, a total of 4 relevant studies were included and reviewed. Conclusion Intravenous TXA is established as an efficacious hemostatic agent in spinal surgery. Use of topical TXA in surgery suggests similar hemostatic efficacy and potentially improved safety as compared with intravenous TXA. For spinal surgery, the literature on topical TXA is sparse but promising, warranting further clinical investigation and consideration as a clinical option in cases with significant anticipated surgical site blood loss. PMID:27099820
Topical Prophylaxis for HIV Prevention in Women: Becoming a Reality
Verma, Natasha A.; Lee, Anna C.; Herold, Betsy C.
2011-01-01
Strategies to protect against sexual transmission of HIV include the development of products formulated for topical application, which limit the toxicities associated with systemic oral pre-exposure prophylaxis. Following several clinical trial failures, attention is now focused on antiretroviral (ARV) agents. Highly potent ARV topical formulations provide a female-controlled, targeted, and feasible option for HIV prevention. A recently completed tenofovir gel trial was the first to demonstrate significant protection against HIV acquisition. Topical ARVs have the advantage of delivering high concentration of drug at the site of transmission of HIV, with low systemic absorption. Sustained-release formulations, such as intravaginal rings, will likely improve adherence and can be designed to provide controlled and continuous delivery of ARV combinations. Further studies to test alternative dosing strategies and pharmacokinetic/pharmacodynamic relationships in the genital tract will provide valuable information as the field strives to improve upon the promising tenofovir gel trial results. PMID:21424725
Comparing Three Innovative Instructional Systems.
ERIC Educational Resources Information Center
Dunn, Rita; Waggoner, Barbara
1995-01-01
Examines the differences between three instructional systems: learning styles, neuro-linguistic programming, and "Suggestopoedia." Topics include the philosophical basis of each system; teaching methodologies; the use of multimedia; the use of time; environmental settings; and approaches to human emotion, individual sociological differences, and…
Distributed Space System Technology Demonstrations with the Emerald Nanosatellite
NASA Technical Reports Server (NTRS)
Twiggs, Robert
2002-01-01
A viewgraph presentation of Distributed Space System Technologies utilizing the Emerald Nanosatellite is shown. The topics include: 1) Structure Assembly; 2) Emerald Mission; 3) Payload and Mission Operations; 4) System and Subsystem Description; and 5) Safety Integration and Testing.
Proceedings of the 1987 IEEE international conference on systems, man, and cybernetics. Volume 1
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1987-01-01
This book contains the proceedings of the IEE international conference on systems Man, and cybernetics. Topics include the following: robotics; knowledge base simulation; software systems, image and pattern recognition; neural networks; and image processing.
ERIC Educational Resources Information Center
Bilal, Dania; Barry, Jeff; Penniman, W. David
1999-01-01
Reviews automated-systems activities in libraries during the past year and profiles major vendors. Topics include new partnership arrangements driven by competition; library-systems revenues; Y2K issues; Windows-based interfaces; consulting; outsourcing; development trends; global system sales; and sales by type of library. (LRW)
Proceedings of the 2nd Annual Conference on NASA/University Advanced Space Design Program
NASA Technical Reports Server (NTRS)
1986-01-01
Topics discussed include: lunar transportation system, Mars rover, lunar fiberglass production, geosynchronous space stations, regenerative system for growing plants, lunar mining devices, lunar oxygen transporation system, mobile remote manipulator system, Mars exploration, launch/landing facility for a lunar base, and multi-megawatt nuclear power system.
A Vision for Systems Engineering Applied to Wind Energy (Presentation)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Felker, F.; Dykes, K.
2015-01-01
This presentation was given at the Third Wind Energy Systems Engineering Workshop on January 14, 2015. Topics covered include the importance of systems engineering, a vision for systems engineering as applied to wind energy, and application of systems engineering approaches to wind energy research and development.
SSTAC/ARTS review of the draft Integrated Technology Plan (ITP). Volume 5: Human Support
NASA Technical Reports Server (NTRS)
1991-01-01
Viewgraphs of briefings from the Space Systems and Technology Advisory Committee (SSTAC)/ARTS review of the draft integrated technology plan (ITP) on human support are included. Topics covered include: human support program; human factors; life support technology; fire safety; medical support technology; advanced refrigeration technology; EVA suit system; advanced PLSS technology; and ARC-EVA systems research program.
NASA Technical Reports Server (NTRS)
1975-01-01
Technological information is presented electronic circuits and systems which have potential utility outside the aerospace community. Topics discussed include circuit components such as filters, converters, and integrators, circuits designed for use with specific equipment or systems, and circuits designed primarily for use with optical equipment or displays.
Proceedings of the 1984 IEEE international conference on systems, man and cybernetics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1984-01-01
This conference contains papers on artificial intelligence, pattern recognition, and man-machine systems. Topics considered include concurrent minimization, a robot programming system, system modeling and simulation, camera calibration, thermal power plants, image processing, fault diagnosis, knowledge-based systems, power systems, hydroelectric power plants, expert systems, and electrical transients.
Systems concepts: Lectures on contemporary approaches to systems.
NASA Technical Reports Server (NTRS)
Miles, R. F., Jr.
1973-01-01
Collection of papers dealing with the application of systems concepts to a wide range of disciplines. The topics include systems definitions and designs, models for systems engineering, the evolution of the JPL, systems concepts in lunar and planetary projects, civil systems projects, and Apollo program evaluation. Individual items are announced in this issue.
Design, Development and Utilization Perspectives on Database Management Systems
ERIC Educational Resources Information Center
Shneiderman, Ben
1977-01-01
This paper reviews the historical development of integrated data base management systems and examines competing approaches. Topics include management and utilization, implementation and design, query languages, security, integrity, privacy and concurrency. (Author/KP)
Proceedings: Computer Science and Data Systems Technical Symposium, volume 1
NASA Technical Reports Server (NTRS)
Larsen, Ronald L.; Wallgren, Kenneth
1985-01-01
Progress reports and technical updates of programs being performed by NASA centers are covered. Presentations in viewgraph form are included for topics in three categories: computer science, data systems and space station applications.
The Solidification of Multicomponent Alloys
Boettinger, William J.
2017-01-01
Various topics taken from the author’s research portfolio that involve multicomponent alloy solidification are reviewed. Topics include: ternary eutectic solidification and Scheil-Gulliver paths in ternary systems. A case study of the solidification of commercial 2219 aluminum alloy is described. Also described are modifications of the Scheil-Gulliver analysis to treat dendrite tip kinetics and solid diffusion for multicomponent alloys. PMID:28819348
Coordinating Council. Second Meeting: International Acquisitions
NASA Technical Reports Server (NTRS)
1990-01-01
The theme of this NASA Scientific and Technical Information Program Coordinating Council was International Acquisitions. Included are both visuals for presentations and reports on discussions related to the topics. Presentations were made on the following topics: Coordination council organization international plan, STI global network, International aerospace climate, Foreign exchange program, Foreign activities RMS & AIAA, NASA translation program, A.F. machine translation system, and CIRC cooperation.
Proceedings of the 2nd NASA Ada User's Symposium
NASA Technical Reports Server (NTRS)
1989-01-01
Several presentations, mostly in viewgraph form, on various topics relating to Ada applications are given. Topics covered include the use of Ada in NASA, Ada and the Space Station, the software support environment, Ada in the Software Engineering Laboratory, Ada at the Jet Propulsion Laboratory, the Flight Telerobotic Servicer, and lessons learned in prototyping the Space Station Remote Manipulator System control.
ERIC Educational Resources Information Center
Perikos, Isidoros; Grivokostopoulou, Foteini; Hatzilygeroudis, Ioannis
2017-01-01
Logic as a knowledge representation and reasoning language is a fundamental topic of an Artificial Intelligence (AI) course and includes a number of sub-topics. One of them, which brings difficulties to students to deal with, is converting natural language (NL) sentences into first-order logic (FOL) formulas. To assist students to overcome those…
Aerospace Medicine and Biology: A continuing bibliography with indexes, supplement 217, March 1981
NASA Technical Reports Server (NTRS)
1981-01-01
Approximately 130 reports, articles, and other documents introduced into the NASA scientific and technical information system in February 1981 are included in this bibliography. Topics include aerospace medicine and biology.
Geothermal systems materials: a workshop/symposium
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1978-01-01
Sixteen papers are included. A separate abstract was prepared for each. Summaries of workshops on the following topics are also included in the report: non-metallic materials, corrosion, materials selection, fluid chemistry, and failure analysis. (MHR)
Data collection with the ACTS propagation terminal
NASA Technical Reports Server (NTRS)
Remaklus, Will
1993-01-01
Viewgraphs on data collection with the ACTS propagation terminal are included. Topics covered include: DACS system overview; DACS board; APT data collection computer; APT software downloading; data storage for APT; and ACTS propagation experiment data flow.
UHMS position statement: topical oxygen for chronic wounds.
Feldmeier, J J; Hopf, H W; Warriner, R A; Fife, C E; Gesell, L B; Bennett, M
2005-01-01
A small body of literature has been published reporting the application of topical oxygen for chronic non-healing wounds . Frequently, and erroneously, this form of oxygen administration has been referred to as "topical hyperbaric oxygen therapy" or even more erroneously "hyperbaric oxygen therapy." The advocates of topical oxygen claim several advantages over systemic hyperbaric oxygen including decreased cost, increased safety, decreased complications and putative physiologic effects including decreased free radical formation and more efficient delivery of oxygen to the wound surface. With topical oxygen an airtight chamber or polyethylene bag is sealed around a limb or the trunk by either a constriction/tourniquet device or by tape and high flow (usually 10 liters per minute) oxygen is introduced into the bag and over the wound. Pressures just over 1.0 atmospheres absolute (atm abs) (typically 1.004 to 1.013 atm abs) are recommended because higher pressures could decrease arterial/capillary inflow. The premise for topical oxygen, the diffusion of oxygen into the wound adequate to enhance healing, is attractive (though not proven) and its delivery is certainly less complex and expensive than hyperbaric oxygen. When discussing the physiology of topical oxygen, its proponents frequently reference studies of systemic hyperbaric oxygen suggesting that mechanisms are equally applicable to both topical and systemic high pressure oxygen delivery. In fact, however, the two are very different. To date, mechanisms of action whereby topical oxygen might be effective have not been defined or substantiated. Conversely, cellular toxicities due to extended courses of topical oxygen have been reported, although, again these data are not conclusive, and no mechanism for toxicity has been examined scientifically. Generally, collagen production and fibroblast proliferation are considered evidence of improved healing, and these are both enhanced by hyperbaric oxygen therapy. Paradoxically, claims of decreased collagen production and fibroblast inhibition in wounds subjected to topical oxygen have been reported in studies of topical oxygen as a benefit of topical oxygen therapy. The literature on topical oxygen is mostly small case series or small controlled but not randomized trials. Moreover, the studies generally are not aimed at specific ulcer types, but rather at "chronic wounds." This non-specific approach is recognized as a major design flaw in any study of therapies designed to improve impaired wound healing. The only randomized trial for topical oxygen in diabetic foot ulcers actually showed a tendency toward impaired wound healing in the topical oxygen group. Contentions that topical oxygen is superior to hyperbaric oxygen are not proven. There are potentially plausible mechanisms that support both possibly beneficial and detrimental effects of topical oxygen therapy, and thus well designed and executed basic science research and clinical trials are clearly needed. There is some ongoing research in regard to the role of topical oxygen at established wound laboratories. Neither CMS nor other third party payors recognize or reimburse for topical oxygen. Therefore, the policy of the Undersea and Hyperbaric Medical Society in regard to topical oxygen is stated as follows: 1. Topical oxygen should not be termed hyperbaric oxygen since doing so either intentionally or unintentionally suggests that topical oxygen treatment is equivalent or even identical to hyperbaric oxygen. Published documents reporting experience with topical oxygen should clearly state that topical oxygen not hyperbaric oxygen is being employed. 2. Mechanisms of action or clinical study results for hyperbaric oxygen cannot and should not be co-opted to support topical oxygen since hyperbaric oxygen therapy and topical oxygen have different routes and probably efficiencies of entry into the wound and their physiology and biochemistry are necessarily different. 3. The application of topical oxygen cannot be recommended outside of a clinical trial at this time based on the volume and quality of scientific supporting evidence available, nor does the Society recommend third party payor reimbursement. 4. Before topical oxygen can be recommended as therapy for non-healing wounds, its application should be subjected to the same intense scientific scrutiny to which systemic hyperbaric oxygen has been held.
NASA Earth Resources Survey Symposium. Volume 1-B: Geology, Information Systems and Services
NASA Technical Reports Server (NTRS)
1975-01-01
A symposium was conducted on the practical applications of earth resources survey technology including utilization and results of data from programs involving LANDSAT, the Skylab earth resources experiment package, and aircraft. Topics discussed include geological structure, landform surveys, energy and extractive resources, and information systems and services.
ERIC Educational Resources Information Center
Arasmith, E. E.
This lesson is the second of a two-part series on anaerobic digestion. Topics discussed include classification of digester by function, roof design, and temperature range, mixing systems, gas system components, operational control basics, and general safety considerations. The lesson includes an instructor's guide and student workbook. The…
Transdermal patches: history, development and pharmacology
Pastore, Michael N; Kalia, Yogeshvar N; Horstmann, Michael; Roberts, Michael S
2015-01-01
Transdermal patches are now widely used as cosmetic, topical and transdermal delivery systems. These patches represent a key outcome from the growth in skin science, technology and expertise developed through trial and error, clinical observation and evidence-based studies that date back to the first existing human records. This review begins with the earliest topical therapies and traces topical delivery to the present-day transdermal patches, describing along the way the initial trials, devices and drug delivery systems that underpin current transdermal patches and their actives. This is followed by consideration of the evolution in the various patch designs and their limitations as well as requirements for actives to be used for transdermal delivery. The properties of and issues associated with the use of currently marketed products, such as variability, safety and regulatory aspects, are then described. The review concludes by examining future prospects for transdermal patches and drug delivery systems, such as the combination of active delivery systems with patches, minimally invasive microneedle patches and cutaneous solutions, including metered-dose systems. PMID:25560046
Exploring supervised and unsupervised methods to detect topics in biomedical text
Lee, Minsuk; Wang, Weiqing; Yu, Hong
2006-01-01
Background Topic detection is a task that automatically identifies topics (e.g., "biochemistry" and "protein structure") in scientific articles based on information content. Topic detection will benefit many other natural language processing tasks including information retrieval, text summarization and question answering; and is a necessary step towards the building of an information system that provides an efficient way for biologists to seek information from an ocean of literature. Results We have explored the methods of Topic Spotting, a task of text categorization that applies the supervised machine-learning technique naïve Bayes to assign automatically a document into one or more predefined topics; and Topic Clustering, which apply unsupervised hierarchical clustering algorithms to aggregate documents into clusters such that each cluster represents a topic. We have applied our methods to detect topics of more than fifteen thousand of articles that represent over sixteen thousand entries in the Online Mendelian Inheritance in Man (OMIM) database. We have explored bag of words as the features. Additionally, we have explored semantic features; namely, the Medical Subject Headings (MeSH) that are assigned to the MEDLINE records, and the Unified Medical Language System (UMLS) semantic types that correspond to the MeSH terms, in addition to bag of words, to facilitate the tasks of topic detection. Our results indicate that incorporating the MeSH terms and the UMLS semantic types as additional features enhances the performance of topic detection and the naïve Bayes has the highest accuracy, 66.4%, for predicting the topic of an OMIM article as one of the total twenty-five topics. Conclusion Our results indicate that the supervised topic spotting methods outperformed the unsupervised topic clustering; on the other hand, the unsupervised topic clustering methods have the advantages of being robust and applicable in real world settings. PMID:16539745
NASA Technical Reports Server (NTRS)
Kutler, Paul; Yee, Helen
1987-01-01
Topics addressed include: numerical aerodynamic simulation; computational mechanics; supercomputers; aerospace propulsion systems; computational modeling in ballistics; turbulence modeling; computational chemistry; computational fluid dynamics; and computational astrophysics.
Applications of Tethers in Space, Volume 2
NASA Technical Reports Server (NTRS)
Cron, A. C. (Compiler)
1985-01-01
Topics discussed include tethered satellites, tether deployment, satellite systems, science applications, electrodynamic interactions, transportation applications, artificial gravity, constellations, and technology and testing.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Appel, S.H.
1988-01-01
The topics covered in this book include: Duchenne muscular dystrophy: DNA diagnosis in practice; Central nervous system magnetic resonance imaging; and Magnetic resonance spectroscopy of neurologic diseases.
Nervous System Complexity Baffles Scientists.
ERIC Educational Resources Information Center
Fox, Jeffrey L.
1982-01-01
New research findings about how nerve cells transmit signals are forcing researchers to overhaul their simplistic ideas about the nervous system. Topics highlighted include the multiple role of peptides in the nervous system, receptor molecules, and molecules that form ion channels within membranes. (Author/JN)
How to Choose a Media Retrieval System.
ERIC Educational Resources Information Center
Huber, Joe
1995-01-01
Provides guidelines for schools choosing a media retrieval system. Topics include broadband, baseband, coaxial cable, or fiber optic decisions; the control network; selecting scheduling software; presentation software; device control; control from the classroom; and a comparison of systems offered by five companies. (LRW)
Building a Secure Library System.
ERIC Educational Resources Information Center
Benson, Allen C.
1998-01-01
Presents tips for building a secure library system to guard against threats like hackers, viruses, and theft. Topics include: determining what is at risk; recovering from disasters; developing security policies; developing front-end security; securing menu systems; accessing control programs; protecting against damage from viruses; developing…
Introduction to the Systems Approach at University.
ERIC Educational Resources Information Center
Niemi, Antti J.
1988-01-01
Recommends systems subjects as part of college curricula for providing students with broader skills and with background that does not become outdated. Topics included are requirements of a basic examination, cooperation with other professionals, and examples of systems technologies and interdisciplinary research. (Author/YP)
Topical NSAIDs for acute pain in adults
Massey, Thomas; Derry, Sheena; Moore, R Andrew; McQuay, Henry J
2014-01-01
Background Use of topical NSAIDs to treat acute musculoskeletal conditions is widely accepted in some parts of the world, but not in others. Their main attraction is their potential to provide pain relief without associated systemic adverse events. Objectives To review the evidence from randomised, double-blind, controlled trials on the efficacy and safety of topically applied NSAIDs in acute pain. Search methods We searched MEDLINE, EMBASE, The Cochrane Library, and our own in-house database to December 2009. We sought unpublished studies by asking personal contacts and searching on-line clinical trial registers and manufacturers web sites. Selection criteria We included randomised, double-blind, active or placebo (inert carrier)-controlled trials in which treatments were administered to adult patients with acute pain resulting from strains, sprains or sports or overuse-type injuries (twisted ankle, for instance). There had to be at least 10 participants in each treatment arm, with application of treatment at least once daily. Data collection and analysis Two review authors independently assessed trial quality and validity, and extracted data. Numbers of participants achieving each outcome were used to calculate relative risk and numbers needed to treat (NNT) or harm (NNH) compared to placebo or other active treatment. Main results Forty-seven studies were included; most compared topical NSAIDs in the form of a gel, spray, or cream with a similar placebo, with 3455 participants in the overall analysis of efficacy. For all topical NSAIDs combined, compared with placebo, the number needed to treat to benefit (NNT) for clinical success, equivalent to 50% pain relief, was 4.5 (3.9 to 5.3) for treatment periods of 6 to 14 days. Topical diclofenac, ibuprofen, ketoprofen, and piroxicam were of similar efficacy, but indomethacin and benzydamine were not significantly better than placebo. Local skin reactions were generally mild and transient, and did not differ from placebo. There were very few systemic adverse events or withdrawals due to adverse events. There were insufficient data to reliably compare individual topical NSAIDs with each other or the same oral NSAID. Authors’ conclusions Topical NSAIDs can provide good levels of pain relief, without the systemic adverse events associated with oral NSAIDs, when used to treat acute musculoskeletal conditions. PMID:20556778
Marketing Development Information in South Asia.
ERIC Educational Resources Information Center
Geethananda, Hemamalee
1993-01-01
Discusses adapting traditional marketing strategies for the nonprofit sector, including libraries and information centers, and describes experiences of the Development Information Network for South Asia in Sri Lanka. Topics addressed include librarians' value systems, including free access to information; the need for information marketing;…
Beyond Web-Based Training: Learning Unplugged.
ERIC Educational Resources Information Center
Gayeski, Diane M.
2002-01-01
Discussion of corporate training focuses on the Internet, Web-based training, and the latest trend toward wireless technology. Topics include the emerging workplace, including continuous learning and collaboration and aiding performance; mobile delivery systems for corporate instructional designers; and types of mobile devices, including PDAs…
Development and Evaluation of Topical Gabapentin Formulations
Alcock, Natalie; Hiom, Sarah; Birchall, James C.
2017-01-01
Topical delivery of gabapentin is desirable to treat peripheral neuropathic pain conditions whilst avoiding systemic side effects. To date, reports of topical gabapentin delivery in vitro have been variable and dependent on the skin model employed, primarily involving rodent and porcine models. In this study a variety of topical gabapentin formulations were investigated, including Carbopol® hydrogels containing various permeation enhancers, and a range of proprietary bases including a compounded Lipoderm® formulation; furthermore microneedle facilitated delivery was used as a positive control. Critically, permeation of gabapentin across a human epidermal membrane in vitro was assessed using Franz-type diffusion cells. Subsequently this data was contextualised within the wider scope of the literature. Although reports of topical gabapentin delivery have been shown to vary, largely dependent upon the skin model used, this study demonstrated that 6% (w/w) gabapentin 0.75% (w/w) Carbopol® hydrogels containing 5% (w/w) DMSO or 70% (w/w) ethanol and a compounded 10% (w/w) gabapentin Lipoderm® formulation were able to facilitate permeation of the molecule across human skin. Further pre-clinical and clinical studies are required to investigate the topical delivery performance and pharmacodynamic actions of prospective formulations. PMID:28867811
Microemulsion and Microemulsion-Based Gels for Topical Antifungal Therapy with Phytochemicals.
Boonme, Prapaporn; Kaewbanjong, Jarika; Amnuaikit, Thanaporn; Andreani, Tatiana; Silva, Amélia M; Souto, Eliana B
2016-01-01
Skin fungal infections are regular injuries suffered by people living in tropical areas. Most common pathogens are Trichophyton, Microsporum and Epidermophyton which can cause skin lesions in many parts of body. Topical antifungal phytochemicals are commonly used to avoid systemic adverse events and are more convenient for patient application than those administered by other routes. However, the effectiveness of topical treatments in eradicating fungal infection is more limited since the stratum corneum acts as the skin barrier, resulting in long treatment duration and low patient's compliance. The goal of this work is to identify optimized drug delivery systems to improve topic clinical efficacy. Microemulsions i.e. liquid dispersions of oil and water stabilized with an interfacial film of surfactant are well known drug delivery systems. A thickening agent may be included to form microemulsion-based gels to increase skin adhesion. Microemulsions and microemulsion-based gels can be loaded with several hydrophilic and lipophilic drugs because they are composed of both water and oil phases. Microemulsions and microemulsion-based gels can also be used for the delivery of many drugs including antifungal drugs through stratum corneum due to their capacity to act as skin penetration enhancement. In addition to a comprehensive review of microemulsion and microemulsion-based gels as suitable carriers for skin delivery of various antifungal drugs, this review also aims to discuss the delivery of antifungal phytochemicals.
Fourth NASA Langley Formal Methods Workshop
NASA Technical Reports Server (NTRS)
Holloway, C. Michael (Compiler); Hayhurst, Kelly J. (Compiler)
1997-01-01
This publication consists of papers presented at NASA Langley Research Center's fourth workshop on the application of formal methods to the design and verification of life-critical systems. Topic considered include: Proving properties of accident; modeling and validating SAFER in VDM-SL; requirement analysis of real-time control systems using PVS; a tabular language for system design; automated deductive verification of parallel systems. Also included is a fundamental hardware design in PVS.
Real-World Water System Lead and Copper Corrosion Control
This presentation provides specific background on lead and copper corrosion control chemistry and strategies, and integrates it with other important distribution system corrosion control objectives. Topics covered include: driving force for corrosion (oxidants); impacts of oxida...
NASA Tech Briefs, December 1991. Volume 15, No. 12
NASA Technical Reports Server (NTRS)
1991-01-01
Topics include: Electronic Components and Circuits. Electronic Systems, Physical Sciences, Materials, Computer Programs, Mechanics, Machinery, Fabrication Technology, Mathematics and Information Sciences,
NASA Tech Briefs, December 2002
NASA Technical Reports Server (NTRS)
2002-01-01
Topics covered include: Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; and Life Sciences.
Conference Abstracts: AEDS '84.
ERIC Educational Resources Information Center
Baird, William E.
1985-01-01
The Association of Educational Data Systems (AEDS) conference included 102 presentations. Abstracts of seven of these presentations are provided. Topic areas considered include LOGO, teaching probability through a computer game, writing effective computer assisted instructional materials, computer literacy, research on instructional…
Update on the Systemic Risks of Superpotent Topical Steroids.
Nakamura, Mio; Abrouk, Michael; Zhu, Henry; Farahnik, Benjamin; Koo, John; Bhutani, Tina
2017-07-01
INTRODUCTION: The potential for systemic effects due to percutaneous absorption of superpotent topical steroids has been a longstanding concern. The Food and Drug Administration currently recommends limiting the use of superpotent topical steroids to 50g per week for 2 or 4 consecutive weeks depending on the formulation, which is mostly based on the exact duration with which phase 3 clinical trials were allowed to be conducted per the FDA. This article reviews all published clinical incidence of adrenal adverse effects in the medical literature, specifically Cushing's syndrome (CS) and pathologic adrenal suppression (PAAS), to try to ascertain a more realistic limit for the safe use of superpotent topical steroids as it pertains to its potential systemic effects.
METHODS: Literature search was conducted using PubMed. Only cases of CS and PAAS secondary to the use of Class I superpotent topical steroids were included. Pediatric cases and full articles unavailable in English were excluded.
RESULTS: There were a total of 14 cases of CS and 5 cases of subsequent PAAS found in the current literature.
DISCUSSION: From our review of these cases, if the amount used per week is within FDA guidelines, it appears that patients needed to use superpotent topical steroids for far greater than 2 or 4 weeks to develop CS or PAAS. CS did not necessarily predict occurrence of PAAS, but in all cases CS appeared to be a prerequisite for developing PAAS. All cases of CS and all but one case of PAAS were reversible. If excessive amount of greater than 50g per week is avoided, it appears that superpotent topical steroids may be safe to use consecutively for months, perhaps even years, without causing systemic effects.
J Drugs Dermatol. 2017;16(7):643-648.
.Coherent systems in the terahertz frequency range: Elements, operation, and examples
NASA Technical Reports Server (NTRS)
Goldsmith, Paul F.
1992-01-01
The topics are presented in viewgraph form and include the following: terahertz coherent systems applications; a brief overview of selected components; radiometry and spectroscopy--astronomy; radiometry--aircraft all weather landing system; radiometry--atmospheric remote sensing; plasma diagnostics; communications; radar systems; and materials measurement and manufacturing process control.
Research in Distance Education: A System Modeling Approach.
ERIC Educational Resources Information Center
Saba, Farhad; Twitchell, David
1988-01-01
Describes how a computer simulation research method can be used for studying distance education systems. Topics discussed include systems research in distance education; a technique of model development using the System Dynamics approach and DYNAMO simulation language; and a computer simulation of a prototype model. (18 references) (LRW)
From Information Center to Discovery System: Next Step for Libraries?
ERIC Educational Resources Information Center
Marcum, James W.
2001-01-01
Proposes a discovery system model to guide technology integration in academic libraries that fuses organizational learning, systems learning, and knowledge creation techniques with constructivist learning practices to suggest possible future directions for digital libraries. Topics include accessing visual and continuous media; information…
TREC Initiative with Cheshire II.
ERIC Educational Resources Information Center
Larson, Ray R.
2001-01-01
Describes the University of California at Berkeley's participation in the TREC (Text Retrieval Conference) interactive track experiments. Highlights include results of searches on two systems, Cheshire II and ZPRISE; system design goals and implementation; precision and recall results; search questions by topic and system; and results of…
Safety of available and emerging drug therapies for hyperhidrosis.
Hosp, Christine; Hamm, Henning
2017-09-01
Hyperhidrosis affects 4.8% of the U.S. population and has been underestimated by physicians for long time despite considerable interference with quality of life. Many patients suffer from primary (idiopathic) hyperhidrosis which results from over-activity of sympathetic nerves and is restricted to specific body areas, mostly the axillae, palms, soles, or head. Secondary hyperhidrosis is caused by an underlying disease or the intake of medications and often involves large parts of the body. Numerous effective therapies with topical or systemic drugs and surgical options are available. Areas covered: Efficacy and safety data on aluminum salts, anticholinergic drugs for topical or systemic application, and on intradermal botulinum toxin injections used to treat hyperhidrosis are critically evaluated, including data from clinical trials with focus on possible side effects and long-term complications in dispute. Expert opinion: Hyperhidrosis often responds well to available therapies. Depending on the type of hyperhidrosis treatment should be topical/local or systemic. Most of the side effects are mild, transient and easily manageable. In case of systemic treatment with anticholinergics low dosing and up-titration of medication is necessary to avoid severe adverse effects. Concerns about the promotion of breast cancer and Alzheimer disease by topical aluminum salts are unsolved.
System dynamics in medical education: a tool for life.
Rubin, David M; Richards, Christopher L; Keene, Penelope A C; Paiker, Janice E; Gray, A Rosemary T; Herron, Robyn F R; Russell, Megan J; Wigdorowitz, Brian
2012-05-01
A course in system dynamics has been included in the first year of our university's six-year medical curriculum. System Dynamics is a discipline that facilitates the modelling, simulation and analysis of a wide range of problems in terms of two fundamental concepts viz. rates and levels. Many topics encountered in the medical school curriculum, from biochemistry to sociology, can be understood in this way. The course was introduced following a curriculum review process in which it was concluded that knowledge of systems would serve to enhance problem-solving skills and clinical reasoning. The specific characteristics of system dynamics, the widespread use of digital computers, and the availability of suitable software made it possible to introduce the course at this level. The syllabus comprises a brief review of relevant mathematics followed by system dynamics topics taught in the context of examples, which are primarily but not exclusively medical. It is anticipated that this will introduce new thought processes to medical students, including holistic thinking and improved graphical visualisation skills.
Fölster-Holst, R; Abeck, D; Torrelo, A
2016-03-01
Hydrocortisone 17-butyrate 21-propionate (hydrocortisone buteprate, HBP) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. HBP is available as a 0.1% cream or ointment formulation. Good results were obtained with a once-daily topical treatment. HBP is characterized by a strong topical anti-inflammatory activity and weak systemic action. It is considered to have potency comparable to that of betamethasone 17-valerate (BV), but its systemic effects are less pronounced. HBP was shown to have a good efficacy in the treatment of various oozing and lichenified eczematous skin diseases including atopic dermatitis (AD) and in the treatment of psoriasis vulgaris. Even in very young children, HBP proved successful as an effective and safe drug. A therapeutic index of 2.0 can be attributed to this glucocorticoid. In this respect, there is no difference between topical HBP and other topical glucocorticoids with increased benefit/risk ratio, e.g. prednicarbate (PC), methylprednisolone aceponate (MPA) and mometasone furoate (MM).
Applications of Tethers in Space, Volume 1
NASA Technical Reports Server (NTRS)
Cron, A. C. (Compiler)
1985-01-01
The tethered satellite system is described including tether fundamentals. Applications of very long tethers in space to a broad spectrum of future space missions are explored. Topics covered include: science, transportation, constellations, artificial gravity, technology and test, and electrodynamic interactions. Recommendations to NASA are included.
Development of intelligent robots - Achievements and issues
NASA Astrophysics Data System (ADS)
Nitzan, D.
1985-03-01
A flexible, intelligent robot is regarded as a general purpose machine system that may include effectors, sensors, computers, and auxiliary equipment and, like a human, can perform a variety of tasks under unpredictable conditions. Development of intelligent robots is essential for increasing the growth rate of today's robot population in industry and elsewhere. Robotics research and development topics include manipulation, end effectors, mobility, sensing (noncontact and contact), adaptive control, robot programming languages, and manufacturing process planning. Past achievements and current issues related to each of these topics are described briefly.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hanham, R.; Vogt, W.G.; Mickle, M.H.
1986-01-01
This book presents the papers given at a conference on computerized simulation. Topics considered at the conference included expert systems, modeling in electric power systems, power systems operating strategies, energy analysis, a linear programming approach to optimum load shedding in transmission systems, econometrics, simulation in natural gas engineering, solar energy studies, artificial intelligence, vision systems, hydrology, multiprocessors, and flow models.
About Using the Metric System.
ERIC Educational Resources Information Center
Illinois State Office of Education, Springfield.
This booklet contains a brief introduction to the use of the metric system. Topics covered include: (1) what is the metric system; (2) how to think metric; (3) some advantages of the metric system; (4) basics of the metric system; (5) how to measure length, area, volume, mass and temperature the metric way; (6) some simple calculations using…
NASA Tech Briefs, November 1991. Volume 15, No. 11
NASA Technical Reports Server (NTRS)
1991-01-01
Topics include: Electronic Components & and Circuits. Electronic Systems, Physical Sciences, Materials, Computer Programs, Mechanics, Machinery, Fabrication Technology, and Mathematics and Information Sciences,
Safety Review Panel (SRP) Special Topic Presentation on the Iodine Compatible Water Container (ICWC)
NASA Technical Reports Server (NTRS)
Thomas, Evan A.
2008-01-01
This viewgraph presentation reviews the safety requirements for the Iodine Compatible Water Container (ICWC). The topics include: 1) ICWC Team; 2) Purpose of presentation; 3) Background/Description of ICWC System; 4) Current status of ICWC Project; 5) HTV launch NCR Processing; 6) Tox 1 containment NCR processing; and 7) ISS on-orbit failure propagation and fault tolerance NCR processing.
Selected Topics in Overset Technology Development and Applications At NASA Ames Research Center
NASA Technical Reports Server (NTRS)
Chan, William M.; Kwak, Dochan (Technical Monitor)
2002-01-01
This paper presents a general overview of overset technology development and applications at NASA Ames Research Center. The topics include: 1) Overview of overset activities at NASA Ames; 2) Recent developments in Chimera Grid Tools; 3) A general framework for multiple component dynamics; 4) A general script module for automating liquid rocket sub-systems simulations; and 5) Critical future work.
Technology Evaluation for an Advanced Individual Protection System (AIPS)
1992-12-01
this analysis are: time of operation, duration of thermal management, power consumed during operation, cooling/heating benefit , time between recharge...BRDEC) TOPICS: o individual power * batteries/engines/fuel cel!s POC: Wes Goodwin (NRDEC) TOPICS: * microclimate cooling e vapor compression cycles e...individual power 2.3 LITERATURE SEARCHES The literature searches began by reviewing Battelle in-house sources for useful reports. This included a
Physics at the FQMT'11 conference
NASA Astrophysics Data System (ADS)
Špička, V.; Nieuwenhuizen, Th M.; Keefe, P. D.
2012-11-01
This paper deals with the recent state of the art of the following topics presented at the FQMT'11 conference: foundations of quantum physics, quantum measurement; nonequilibrium quantum statistical physics; quantum thermodynamics; quantum measurement, entanglement and coherence; dissipation, dephasing, noise, and decoherence; quantum optics; macroscopic quantum behavior; e.g. cold atoms; Bose-Einstein condensates; physics of quantum computing and quantum information; mesoscopic, nano-electro-mechanical systems and nano-optical systems; spin systems and their dynamics; biological systems and molecular motors; and cosmology, gravitation and astrophysics. The lectures and discussions at the FQMT'11 conference, as well as the contributions to the related topical issue, reveal important themes for future development. The recent literature is included.
ERIC Educational Resources Information Center
Swan, James
1996-01-01
Presents a four-phase plan for small libraries strategizing for automation: inventory and weeding, data conversion, implementation, and enhancements. Other topics include selecting a system, MARC records, compatibility, ease of use, industry standards, searching capabilities, support services, system security, screen displays, circulation modules,…
Proceedings: Computer Science and Data Systems Technical Symposium, volume 2
NASA Technical Reports Server (NTRS)
Larsen, Ronald L.; Wallgren, Kenneth
1985-01-01
Progress reports and technical updates of programs being performed by NASA centers are covered. Presentations in viewgraph form, along with abstracts, are included for topics in three catagories: computer science, data systems, and space station applications.
Second Annual Conference on Astronomical Data Analysis Software and Systems. Abstracts
NASA Technical Reports Server (NTRS)
1992-01-01
Abstracts from the conference are presented. The topics covered include the following: next generation software systems and languages; databases, catalogs, and archives; user interfaces/visualization; real-time data acquisition/scheduling; and IRAF/STSDAS/PROS status reports.
Aerospace Medicine and Biology: A continuing bibliography, supplement 216
NASA Technical Reports Server (NTRS)
1981-01-01
One hundred twenty reports, articles, and other documents introduced into the NASA scientific and technical information system in January 1981 are listed. Topics include: sanitary problems; pharmacology; toxicology; safety and survival; life support systems; exobiology; and personnel factors.
Building a Unified Information Network.
ERIC Educational Resources Information Center
Avram, Henriette D.
1988-01-01
Discusses cooperative efforts between research organizations and libraries to create a national information network. Topics discussed include the Linked System Project (LSP); technical processing versus reference and research functions; Open Systems Interconnection (OSI) Reference Model; the National Science Foundation Network (NSFNET); and…
Proceedings of the 1991 Symposium on Systems Analysis in Forest Resources
[Compiler
1991-01-01
Forest Service, university, forest industry, and private consulting representatives presented 65 papers. General topic areas include: land management planning, multicriteria optimization, timber harvest scheduling, geographic information systems, sawmill simulation, timber supply analysis, and climate simulation.
CCIR paper on the radiocommunications requirements for systems to search for extraterrestrial life
NASA Technical Reports Server (NTRS)
Nightingale, D.
1978-01-01
The allocation and propagation of radio frequency bands to be used in the search for extraterrestrial intelligence is considered. Topics discussed include: propagation factors; preferred frequency bands; system characteristics and requirements; and interference.
Zeng, Chao; Wei, Jie; Persson, Monica S M; Sarmanova, Aliya; Doherty, Michael; Xie, Dongxing; Wang, YiLun; Li, Xiaoxiao; Li, Jiatian; Long, Huizhong; Lei, Guanghua; Zhang, Weiya
2018-05-01
To compare the efficacy and safety of topical non-steroidal anti-inflammatory drugs (NSAIDs), including salicylate, for the treatment of osteoarthritis (OA). PubMed, Embase, Cochrane Library and Web of Science were searched from 1966 to January 2017. Randomised controlled trials (RCTs) comparing topical NSAIDs with placebo or each other in patients with OA and observational studies comparing topical NSAIDs with no treatment or each other irrespective of disease were included. Two investigators identified studies and independently extracted data. Bayesian network and conventional meta-analyses were conducted. The primary outcomes were pain relief for RCTs and risk of adverse effects (AEs) for observational studies. 43 studies, comprising 36 RCTs (7 900 patients with OA) and seven observational studies (218 074 participants), were included. Overall, topical NSAIDs were superior to placebo for relieving pain (standardised mean difference (SMD)=-0.30, 95% CI -0.40 to -0.20) and improving function (SMD=-0.35, 95% CI -0.45 to -0.24) in OA. Of all topical NSAIDs, diclofenac patches were most effective for OA pain (SMD=-0.81, 95% CI -1.12 to -0.52) and piroxicam was most effective for functional improvement (SMD=-1.04, 95% CI -1.60 to -0.48) compared with placebo. Although salicylate gel was associated with higher withdrawal rates due to AEs, the remaining topical NSAIDs were not associated with any increased local or systemic AEs. Topical NSAIDs were effective and safe for OA. Diclofenac patches may be the most effective topical NSAID for pain relief. No serious gastrointestinal and renal AEs were observed in trials or the general population. However, confirmation of the cardiovascular safety of topical NSAIDs still warrants further observational study. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Persson, Monica S M; Sarmanova, Aliya; Doherty, Michael; Xie, Dongxing; Wang, YiLun; Li, Xiaoxiao; Li, Jiatian; Long, Huizhong
2018-01-01
Objectives To compare the efficacy and safety of topical non-steroidal anti-inflammatory drugs (NSAIDs), including salicylate, for the treatment of osteoarthritis (OA). Methods PubMed, Embase, Cochrane Library and Web of Science were searched from 1966 to January 2017. Randomised controlled trials (RCTs) comparing topical NSAIDs with placebo or each other in patients with OA and observational studies comparing topical NSAIDs with no treatment or each other irrespective of disease were included. Two investigators identified studies and independently extracted data. Bayesian network and conventional meta-analyses were conducted. The primary outcomes were pain relief for RCTs and risk of adverse effects (AEs) for observational studies. Results 43 studies, comprising 36 RCTs (7 900 patients with OA) and seven observational studies (218 074 participants), were included. Overall, topical NSAIDs were superior to placebo for relieving pain (standardised mean difference (SMD)=−0.30, 95% CI −0.40 to –0.20) and improving function (SMD=−0.35, 95% CI −0.45 to –0.24) in OA. Of all topical NSAIDs, diclofenac patches were most effective for OA pain (SMD=−0.81, 95% CI −1.12 to –0.52) and piroxicam was most effective for functional improvement (SMD=−1.04, 95% CI −1.60 to –0.48) compared with placebo. Although salicylate gel was associated with higher withdrawal rates due to AEs, the remaining topical NSAIDs were not associated with any increased local or systemic AEs. Conclusions Topical NSAIDs were effective and safe for OA. Diclofenac patches may be the most effective topical NSAID for pain relief. No serious gastrointestinal and renal AEs were observed in trials or the general population. However, confirmation of the cardiovascular safety of topical NSAIDs still warrants further observational study. PMID:29436380
Educational Technology: Best Practices from America's Schools.
ERIC Educational Resources Information Center
Bozeman, William C.; Baumbach, Donna J.
This book begins with an overview of computer technology concepts, including computer system configurations, computer communications, and software. Instructional computer applications are then discussed; topics include computer-assisted instruction, computer-managed instruction, computer-enhanced instruction, LOGO, authoring programs, presentation…
Making the Math/Science Connection.
ERIC Educational Resources Information Center
Sherman, Laurel Galbraith
1989-01-01
Suggestions are made for activities that combine the teaching of math and science. Math concepts include: graphing, estimating, measurement, statistics, geometry, and logic. Science topics include: plant reproduction, solar system, forces, longitude and latitude, Earth's magnetic field, nutrition, and heat. (IAH)
Archive Storage Media Alternatives.
ERIC Educational Resources Information Center
Ranade, Sanjay
1990-01-01
Reviews requirements for a data archive system and describes storage media alternatives that are currently available. Topics discussed include data storage; data distribution; hierarchical storage architecture, including inline storage, online storage, nearline storage, and offline storage; magnetic disks; optical disks; conventional magnetic…
Science in the city: Urban trees, forests, and people
Kathleen L. Wolf
2016-01-01
The article, intended for professional and manager audiences, is an overview of current research in urban forestry. Topics include tree science, forest risks, forest management and assessment, ecosystem services, and urban socio-ecological systems (including governance and stewardship).
Annual Review of Database Development: 1992.
ERIC Educational Resources Information Center
Basch, Reva
1992-01-01
Reviews recent trends in databases and online systems. Topics discussed include new access points for established databases; acquisitions, consolidations, and competition between vendors; European coverage; international services; online reference materials, including telephone directories; political and legal materials and public records;…
Bibliographic Instruction in the 21st Century.
ERIC Educational Resources Information Center
Poirier, Gayle
2000-01-01
Discusses bibliographic instruction in libraries. Topics include a history of bibliographic instruction; the Internet and electronic searching; librarians' use of technology; defining information needs; locating and accessing information, including classification systems and Boolean searching; evaluating information; using and communication…
ERIC Educational Resources Information Center
Zeman, Anne; Kelly, Kate
This book is written to answer commonly asked homework questions of fourth, fifth, and sixth graders. Included are facts, charts, definitions, explanations, examples, and illustrations. Topics include ancient number systems; decimal system; math symbols; addition; subtraction; multiplication; division; fractions; estimation; averages; properties;…
NASA Space Engineering Research Center for utilization of local planetary resources
NASA Technical Reports Server (NTRS)
1992-01-01
Reports covering the period from 1 Nov. 1991 to 31 Oct. 1992 and documenting progress at the NASA Space Engineering Research Center are included. Topics covered include: (1) processing of propellants, volatiles, and metals; (2) production of structural and refractory materials; (3) system optimization discovery and characterization; (4) system automation and optimization; and (5) database development.
NASA Tech Briefs, November 1997. Volume 21, No. 11
NASA Technical Reports Server (NTRS)
1997-01-01
Topics covered include: Test and Measurement; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Software; Mechanics; Machinery/Automation; Books and Reports..
NASA Tech Briefs, August 1992. Volume 16, No. 8
NASA Technical Reports Server (NTRS)
1992-01-01
Topics include: Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
Supersonic Cruise Research 1979, part 1
NASA Technical Reports Server (NTRS)
1980-01-01
Aerodynamics, stability and control, propulsion, and environmental factors of the supersonic cruise aircraft are discussed. Other topics include airframe structures and materials, systems integration, and economics.
NASA Tech Briefs, September 1992. Volume 16, No.9
NASA Technical Reports Server (NTRS)
1992-01-01
Topics include: Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Technical Reports Server (NTRS)
1985-01-01
Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Life Sciences; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences.
NASA Tech Briefs, January 1993. Volume 17, No. 1
NASA Technical Reports Server (NTRS)
1993-01-01
Topics include: Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences;
NASA Tech Briefs, November 1992. Volume 16, No. 11
NASA Technical Reports Server (NTRS)
1992-01-01
Topics include: Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences;
NASA Tech Briefs, December 1992. Volume 16, No. 12
NASA Technical Reports Server (NTRS)
1992-01-01
Topics include: Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences;
NASA Technical Reports Server (NTRS)
1985-01-01
Topic include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Life Sciences; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences.
Galileo: Exploration of Jupiter's system
NASA Technical Reports Server (NTRS)
Johnson, T. V.; Yeates, C. M.; Colin, L.; Fanale, F. P.; Frank, L.; Hunten, D. M.
1985-01-01
The scientific objectives of the Galileo mission to the Jovian system is presented. Topics discussed include the history of the project, our current knowledge of the system, the objectives of interrelated experiments, mission design, spacecraft, and instruments. The management, scientists, and major contractors for the project are also given.
Providing Access to Library Automation Systems for Students with Disabilities.
ERIC Educational Resources Information Center
California Community Colleges, Sacramento. High-Tech Center for the Disabled.
This document provides information on the integration of assistive computer technologies and library automation systems at California Community Colleges in order to ensure access for students with disabilities. Topics covered include planning, upgrading, purchasing, implementing and using these technologies with library systems. As information…
ERIC Educational Resources Information Center
Folda, Linda; And Others
1989-01-01
Issues related to library online systems are discussed in six articles. Topics covered include staff education through vendor demonstrations, evaluation of online public access catalogs, the impact of integrated online systems on cataloging operations, the merits of smart and dumb barcodes, and points to consider in planning for the next online…
Design Guidelines for CAI Authoring Systems.
ERIC Educational Resources Information Center
Hunka, S.
1989-01-01
Discussion of the use of authoring systems for courseware development focuses on guidelines to be considered when designing authoring systems. Topics discussed include allowing a variety of instructional strategies; interaction with peripheral processes such as student records; the editing process; and human factors in computer interface design,…
Gaylord Information Systems: Poised for Its Second Century.
ERIC Educational Resources Information Center
Farley, Charles E., Jr.; And Others
1993-01-01
Describes the development of the GALAXY Integrated Library System by Gaylord Information Systems. Topics addressed include the library automation business; industry trends, both long-term and short-term; a history of Gaylord's automation ventures; Gaylord's vision of the future; and perspectives from two GALAXY users. (LRW)
Applying Monte Carlo Simulation to Launch Vehicle Design and Requirements Analysis
NASA Technical Reports Server (NTRS)
Hanson, J. M.; Beard, B. B.
2010-01-01
This Technical Publication (TP) is meant to address a number of topics related to the application of Monte Carlo simulation to launch vehicle design and requirements analysis. Although the focus is on a launch vehicle application, the methods may be applied to other complex systems as well. The TP is organized so that all the important topics are covered in the main text, and detailed derivations are in the appendices. The TP first introduces Monte Carlo simulation and the major topics to be discussed, including discussion of the input distributions for Monte Carlo runs, testing the simulation, how many runs are necessary for verification of requirements, what to do if results are desired for events that happen only rarely, and postprocessing, including analyzing any failed runs, examples of useful output products, and statistical information for generating desired results from the output data. Topics in the appendices include some tables for requirements verification, derivation of the number of runs required and generation of output probabilistic data with consumer risk included, derivation of launch vehicle models to include possible variations of assembled vehicles, minimization of a consumable to achieve a two-dimensional statistical result, recontact probability during staging, ensuring duplicated Monte Carlo random variations, and importance sampling.
BMY 30047: A novel topically active retinoid with low local and systemic toxicity
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nair, X.; Quigley, J.; Tramposch, K.M.
In the treatment of various dermatological disorders, topically applied retinoids have potential therapeutic use with the advantage of improved localized activity and lower toxicity over systemically administered retinoids. However, most retinoids cause a significant degree of local irritation. In the present study, the ability to produce local activity with low local irritation potential was evaluated with a novel retinoic acid derivative. BMY 30047 (11-cis, 13-cis-12-hydroxymethylretinoic acid delta-lactone) is one of a series of retinoic acid derivatives in which the carboxyl function of the polar end was modified with the aim of achieving reduced local irritation and systemic toxicity while retainingmore » the local therapeutic effect. BMY 30047 was evaluated and compared with all-trans retinoic acid for topical retinoid activity in several preclinical assay systems, including the utricle reduction assay in rhino mice, 12-o-tetradecanoylphorbol 13-acetate ester-stimulated ornithine decarboxylase induction in hairless mice and the UV light-induced photodamaged skin model in hairless mice. BMY 30047 was assessed for retinoid-type side effects by evaluating the skin irritation potential in rabbits after repeated topical application, and hypervitaminosis A-inducing potential in mice after i.p. injection. BMY 30047 demonstrated significant topical retinoid activity in several in vivo models with less skin irritation potential relative to the most used clinical concentrations of all-trans retinoic acid. BMY 30047 also showed very little systemic activity and did not produce any evidence of hypervitaminosis A syndrome at systemic doses 20 times greater than the no-effect dose of all-trans retinoic acid.« less
A beginner's guide to belief revision and truth maintenance systems
NASA Technical Reports Server (NTRS)
Mason, Cindy L.
1992-01-01
This brief note is intended to familiarize the non-TMS audience with some of the basic ideas surrounding classic TMS's (truth maintenance systems), namely the justification-based TMS and the assumption-based TMS. Topics of further interest include the relation between non-monotonic logics and TMS's, efficiency and search issues, complexity concerns, as well as the variety of TMS systems that have surfaced in the past decade or so. These include probabilistic-based TMS systems, fuzzy TMS systems, tri-valued belief systems, and so on.
NASA Tech Briefs, May 2000. Volume 24, No. 5
NASA Technical Reports Server (NTRS)
2000-01-01
Topics include: Sensors: Test and Measurement; Computer-Aided Design and Engineering; Electronic Components and Circuits; Electronic Systems; Composites and Plastics; Materials; Computer Programs; Mechanics;
NASA Tech Briefs, June 2000. Volume 24, No. 6
NASA Technical Reports Server (NTRS)
2000-01-01
Topics include: Computer-Aided Design and Engineering; Electronic Components and Circuits; Electronic Systems; Test and Measurement; Physical Sciences; Materials; Computer Programs; Computers and Peripherals;
NASA Tech Briefs, October 1989. Volume 13, No. 10
NASA Technical Reports Server (NTRS)
1989-01-01
Topics include: Electronic Components and Circuits. Electronic Systems, Physical Sciences, Materials, Computer Programs, Mechanics, Machinery, Fabrication Technology, Mathematics and Information Sciences, and Life Sciences
NASA Tech Briefs, February 1990. Volume 14, No. 2
NASA Technical Reports Server (NTRS)
1990-01-01
Topics include: Electronic Components and Circuits. Electronic Systems, Physical Sciences, Materials, Computer Programs, Mechanics, Machinery, Fabrication Technology, Mathematics and Information Sciences, and Life Sciences
NASA Tech Briefs, January 1990. Volume 14, No. 1
NASA Technical Reports Server (NTRS)
1990-01-01
Topics include: Electronic Components and Circuits. Electronic Systems, Physical Sciences, Materials, Computer Programs, Mechanics, Machinery, Fabrication Technology, Mathematics and Information Sciences, and Life Sciences
NASA Tech Briefs, November 1989. Volume 13, No. 11
NASA Technical Reports Server (NTRS)
1989-01-01
Topics include: Electronic Components and Circuits. Electronic Systems, Physical Sciences, Materials, Computer Programs, Mechanics, Machinery, Fabrication Technology, Mathematics and Information Sciences, and Life Sciences
Space Station Engineering Design Issues
NASA Technical Reports Server (NTRS)
Mcruer, Duane T.; Boehm, Barry W.; Debra, Daniel B.; Green, C. Cordell; Henry, Richard C.; Maycock, Paul D.; Mcelroy, John H.; Pierce, Chester M.; Stafford, Thomas P.; Young, Laurence R.
1989-01-01
Space Station Freedom topics addressed include: general design issues; issues related to utilization and operations; issues related to systems requirements and design; and management issues relevant to design.
NASA Tech Briefs, September 1989. Volume 13, No. 9
NASA Technical Reports Server (NTRS)
1989-01-01
Topics include: Electronic Components and Circuits. Electronic Systems, Physical Sciences, Materials, Computer Programs, Mechanics, Machinery, Fabrication Technology, Mathematics and Information Sciences, and Life Sciences.
NASA Tech Briefs, October 1992. Volume 16, No. 10
NASA Technical Reports Server (NTRS)
1992-01-01
Topics covered include: Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication technology; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, December 1989. Volume 13, No. 12
NASA Technical Reports Server (NTRS)
1989-01-01
Topics include: Electronic Components and Circuits. Electronic Systems, Physical Sciences, Materials, Computer Programs, Mechanics, Machinery, Fabrication Technology, Mathematics and Information Sciences, and Life Sciences.
NASA Tech Briefs, April 1993. Volume 17, No. 4
NASA Technical Reports Server (NTRS)
1993-01-01
Topics include: Optoelectronics; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences;
NASA Tech Briefs, March 1990. Volume 14, No. 3
NASA Technical Reports Server (NTRS)
1990-01-01
Topics include: Electronic Components and Circuits. Electronic Systems, Physical Sciences, Materials, Computer Programs, Mechanics, Machinery, Fabrication Technology, Mathematics and Information Sciences, and Life Sciences
NASA Astrophysics Data System (ADS)
Cowan, James
This chapter summarizes and explains key concepts of building acoustics. These issues include the behavior of sound waves in rooms, the most commonly used rating systems for sound and sound control in buildings, the most common noise sources found in buildings, practical noise control methods for these sources, and the specific topic of office acoustics. Common noise issues for multi-dwelling units can be derived from most of the sections of this chapter. Books can be and have been written on each of these topics, so the purpose of this chapter is to summarize this information and provide appropriate resources for further exploration of each topic.
Electro optical system to measure strains at high temperature
NASA Astrophysics Data System (ADS)
Sciammarella, Cesar A.
1991-01-01
The goals of this proposal were to develop a prototype of an electro-optics system for the measurement of strains in structures at high temperatures and to perform a test under field conditions. In the research task section, the topics addressed include: (1) correction of the effect of vibrations and thermal currents by means of an active compensation system; (2) reduction of the speckle noise by means of electronic filter and TV signal reconstruction circuit; (4) compensation of the rigid body motions by mounting the camera in a universal motion system; and (5) removal of phase errors left by the active compensation system by dynamic reading. In the design and construction section, the topics addressed include: (1) preliminary design; (2) final design; (3) software development; (4) signal conditioning; (5) data processing; (6) recorrelation of two holograms in the presence of rigid body motions; and (7) phase extraction using a computer generated image. Testing in the high temperature oven is also addressed.
Proceedings 3rd NASA/IEEE Workshop on Formal Approaches to Agent-Based Systems (FAABS-III)
NASA Technical Reports Server (NTRS)
Hinchey, Michael (Editor); Rash, James (Editor); Truszkowski, Walt (Editor); Rouff, Christopher (Editor)
2004-01-01
These preceedings contain 18 papers and 4 poster presentation, covering topics such as: multi-agent systems, agent-based control, formalism, norms, as well as physical and biological models of agent-based systems. Some applications presented in the proceedings include systems analysis, software engineering, computer networks and robot control.
NASA Technical Reports Server (NTRS)
1983-01-01
Various parameters of the orbital space station are discussed. The space station environment, data management system, communication and tracking, environmental control, and life support system are considered. Specific topics reviewed include crew work stations, restraint systems, stowage, computer hardware, and expert systems.
NASA Technical Reports Server (NTRS)
Togai, Masaki
1990-01-01
Viewgraphs on commercial applications of fuzzy logic in Japan are presented. Topics covered include: suitable application area of fuzzy theory; characteristics of fuzzy control; fuzzy closed-loop controller; Mitsubishi heavy air conditioner; predictive fuzzy control; the Sendai subway system; automatic transmission; fuzzy logic-based command system for antilock braking system; fuzzy feed-forward controller; and fuzzy auto-tuning system.
Borio, Stefano; Colombo, Silvia; La Rosa, Giuseppe; De Lucia, Michela; Damborg, Peter; Guardabassi, Luca
2015-10-01
There is a lack of studies comparing topical antiseptics to systemic antibiotics in the treatment of canine superficial pyoderma. To compare the efficacy of topical chlorhexidine with systemic amoxicillin-clavulanic acid for the treatment of canine superficial pyoderma. A randomized controlled trial was conducted in dogs with superficial pyoderma. Group T (n = 31) was treated topically with 4% chlorhexidine digluconate shampoo (twice weekly) and solution (once daily) for 4 weeks. Group S (n = 20) was treated orally with amoxicillin-clavulanic acid (25 mg/kg) twice daily for 4 weeks. Bacterial culture and susceptibility testing were performed on clinical specimens collected before treatment. Severity of lesions and number of intracellular bacteria were evaluated using four-point scales to calculate a total pyoderma score for each dog. Pruritus was assessed by owners using a visual analog scale (range 0-10). Scores were analysed for statistical differences between groups T and S. Staphylococcus pseudintermedius was isolated from 48 dogs, including eight meticillin-resistant strains (MRSP). Although the number of dogs was small, no significant differences in pyoderma and pruritus scores were observed between groups throughout the study except for day 1, when group S had a significantly higher total score than group T (P = 0.03). Treatment with chlorhexidine products resulted in resolution of clinical signs in all dogs including those infected with MRSP. Topical therapy with chlorhexidine digluconate products may be as effective as systemic therapy with amoxicillin-clavulanic acid. This finding supports the current recommendations to use topical antiseptics alone for the management of superficial pyoderma. © 2015 The Authors. Veterinary Dermatology published by John Wiley & Sons Ltd on behalf of the ESVD and ACVD.
Topical anaesthetics for pain control during repair of dermal laceration.
Tayeb, Baraa O; Eidelman, Anthony; Eidelman, Cristy L; McNicol, Ewan D; Carr, Daniel B
2017-02-22
Topical local anaesthetics provide effective analgesia for patients undergoing numerous superficial procedures, including repair of dermal lacerations. The need for cocaine in topical anaesthetic formulations has been questioned because of concern about adverse effects, thus novel preparations of cocaine-free anaesthetics have been developed. This review was originally published in 2011 and has been updated in 2017. To assess whether benefits of non-invasive topical anaesthetic application occur at the expense of decreased analgesic efficacy. To compare the efficacy of various single-component or multi-component topical anaesthetic agents for repair of dermal lacerations. To determine the clinical necessity for topical application of the ester anaesthetic, cocaine. For this updated review, we searched the following databases: Cochrane Central Register of Controlled Trials (CENTRAL; 2016, Issue 11), Cumulative Index to Nursing and Allied Health Literature (CINAHL; 2010 to December 2016), Embase (2010 to December 2016) and MEDLINE (2010 to December 2016). We did not limit this search by language or format of publication. We contacted manufacturers, international scientific societies and researchers in the field. Weemailed selected journalsand reviewed meta-registers of ongoing trials. For the previous version of this review, we searched these databases to November 2010. We included randomized controlled trials (RCTs) that evaluated the efficacy and safety of topical anaesthetics for repair of dermal laceration in adult and paediatric participants. Two review authors independently assessed trial quality and extracted data. We contacted study authors for additional information when needed. We collected adverse event information from trial reports. We assessed methodological risk of bias for each included study and employed the GRADE approach to assess the overall quality of the evidence. The present updated review included 25 RCTs involving 3278 participants. The small number of trials in each comparison group and the heterogeneity of outcome measures precluded quantitative analysis of data for all but one outcome: pain intensity. In two pooled studies, the mean self-reported visual analogue scale (VAS; 0 to 100 mm) score for topical prilocaine-phenylephrine (PP) was higher than the mean self-reported VAS (0 to 100 mm) score for topical tetracaine-epinephrine-cocaine (TAC) by 5.59 points (95% confidence interval (CI) 2.16 to 13.35). Most trials that compared infiltrated and topical anaesthetics were at high risk of bias, which is likely to have affected their results. Researchers found that several cocaine-free topical anaesthetics provided effective analgesic efficacy. However, data regarding the efficacy of each topical agent are based mostly on single comparisons in trials with unclear or high risk of bias. Mild, self-limited erythematous skin induration occurred in one of 1042 participants who had undergone application of TAC. Investigators reported no serious complications among any of the participants treated with cocaine-based or cocaine-free topical anaesthetics. The overall quality of the evidence according to the GRADE system is low owing to limitations in design and implementation, imprecision of results and high probability of publication bias (selective reporting of data). Additional well-designed RCTs with low risk of bias are necessary before definitive conclusions can be reached. We have found two new studies published since the last version of this review was prepared. We have added these studies to those previously included and have conducted an updated analysis, which resulted in the same review conclusions as were presented previously.Mostly descriptive analysis indicates that topical anaesthetics may offer an efficacious, non-invasive means of providing analgesia before suturing of dermal lacerations. Use of cocaine-based topical anaesthetics might be hard to justify, given the availability of other effective topical anaesthetics without cocaine. However, the overall quality of the evidence according to the GRADE system is low owing to limitations in design and implementation, imprecision of results and high probability of publication bias (selective reporting of data). Additional well-designed RCTs with low risk of bias are necessary before definitive conclusions can be reached.
Thermodynamics of Dilute Solutions.
ERIC Educational Resources Information Center
Jancso, Gabor; Fenby, David V.
1983-01-01
Discusses principles and definitions related to the thermodynamics of dilute solutions. Topics considered include dilute solution, Gibbs-Duhem equation, reference systems (pure gases and gaseous mixtures, liquid mixtures, dilute solutions), real dilute solutions (focusing on solute and solvent), terminology, standard states, and reference systems.…
ERIC Educational Resources Information Center
Levy, Sue
1992-01-01
Presents a library automation vendor's perspective on networking based on activities at Ameritech Information Systems. Topics discussed include the information explosion; information technology; user expectations and needs; remote access; the library of the future; systems integration; ownership versus access; copyright laws; and the role of the…
ERIC Educational Resources Information Center
Duchastel, P.; And Others
1989-01-01
Discusses intelligent computer assisted instruction (ICAI) and presents various models of learning which have been proposed. Topics discussed include artificial intelligence; intelligent tutorial systems; tutorial strategies; learner control; system design; learning theory; and knowledge representation of proper and improper (i.e., incorrect)…
Trends in North American intelligent transportation systems : a year 2000 appraisal
DOT National Transportation Integrated Search
2000-04-01
This report examines six specific topics regarding the future of intelligent transportation systems (ITS). Specific objectives in writing this report are to: (1) Provide an overview of the trends for ITS technologies in North America, including marke...
Phase 3 study of selected tether applications in space, mid-term review
NASA Technical Reports Server (NTRS)
1986-01-01
Topics addressed include: guidelines for the Space Transportation System (STS) payload deployer design; mini-orbital maneuvering vehicle (MOMV) design: shuttle tether deployer systems (STEDS); cost modeling; tethered platform analysis; fuel savings analysis; and STEDS control simulation.
Event-Driven X-Ray CCD Detectors for High Energy Astrophysics
NASA Technical Reports Server (NTRS)
Ricker, George R.
2004-01-01
A viewgraph presentation describing the Event-Driven X- Ray CCD (EDCCD) detector system for high energy astrophysics is presented. The topics include: 1) EDCCD: Description and Advantages; 2) Summary of Grant Activity Carried Out; and 3) EDCCD Test System.
Aerospace medicine and biology: A continuing bibliography with indexes, supplement 273
NASA Technical Reports Server (NTRS)
1985-01-01
This bibliography lists 265 reports, articles, and other documents introduced into the NASA scientific and technical information system in June 1985. Topics in aerospace medicine and biology, metabolism, human behavior, man machine systems, and injuries are included.
Quality in Web-Supported Learning.
ERIC Educational Resources Information Center
Fresen, Jill
2002-01-01
Discusses quality assurance for Web-based courses, based on experiences at the University of Pretoria. Topics include evaluation of courseware; the concept of quality, including quality control, quality assurance, and total quality management; implementing a quality management system; measurement techniques; and partnerships. (LRW)
Education, Information Technology and Cognitive Science.
ERIC Educational Resources Information Center
Scaife, M.
1989-01-01
Discusses information technology and its effects on developmental psychology and children's education. Topics discussed include a theory of child-computer interaction (CCI); programing; communication and computers, including electronic mail; cognitive science; artificial intelligence; modeling the user-system interaction; and the future of…
NASA Tech Briefs, September 1995. Volume 19, No. 9
NASA Technical Reports Server (NTRS)
1995-01-01
A special focus for this issue is Sensors. Topics covered include : Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Life Sciences; Mechanics; Machinery; Fabrication Technology; and Mathematics and Information Sciences. A section of Laser Tech Briefs is included.
Expert systems in civil engineering
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kostem, C.N.; Maher, M.L.
1986-01-01
This book presents the papers given at a symposium on expert systems in civil engineering. Topics considered at the symposium included problem solving using expert system techniques, construction schedule analysis, decision making and risk analysis, seismic risk analysis systems, an expert system for inactive hazardous waste site characterization, an expert system for site selection, knowledge engineering, and knowledge-based expert systems in seismic analysis.
Theory and laboratory astrophysics
NASA Technical Reports Server (NTRS)
Schramm, David N.; Mckee, Christopher F.; Alcock, Charles; Allamandola, Lou; Chevalier, Roger A.; Cline, David B.; Dalgarno, Alexander; Elmegreen, Bruce G.; Fall, S. Michael; Ferland, Gary J.
1991-01-01
Science opportunities in the 1990's are discussed. Topics covered include the large scale structure of the universe, galaxies, stars, star formation and the interstellar medium, high energy astrophysics, and the solar system. Laboratory astrophysics in the 1990's is briefly surveyed, covering such topics as molecular, atomic, optical, nuclear and optical physics. Funding recommendations are given for the National Science Foundation, NASA, and the Department of Energy. Recommendations for laboratory astrophysics research are given.
Fuel cell energy storage for Space Station enhancement
NASA Technical Reports Server (NTRS)
Stedman, J. K.
1990-01-01
Viewgraphs on fuel cell energy storage for space station enhancement are presented. Topics covered include: power profile; solar dynamic power system; photovoltaic battery; space station energy demands; orbiter fuel cell power plant; space station energy storage; fuel cell system modularity; energy storage system development; and survival power supply.
Data systems and computer science space data systems: Onboard memory and storage
NASA Technical Reports Server (NTRS)
Shull, Tom
1991-01-01
The topics are presented in viewgraph form and include the following: technical objectives; technology challenges; state-of-the-art assessment; mass storage comparison; SODR drive and system concepts; program description; vertical Bloch line (VBL) device concept; relationship to external programs; and backup charts for memory and storage.
ERIC Educational Resources Information Center
Alabama State Dept. of Education, Montgomery. Div. of Instructional Services.
Topics covered in the first part of this document include eight advantages of the metric system; a summary of metric instruction; the International System of Units (SI) style and usage; metric decimal tables; the metric system; and conversion tables. An alphabetized list of organizations which market metric materials for educators is provided with…
NASA Technical Reports Server (NTRS)
Rodriguez, G. (Editor)
1983-01-01
Two general themes in the control of large space structures are addressed: control theory for distributed parameter systems and distributed control for systems requiring spatially-distributed multipoint sensing and actuation. Topics include modeling and control, stabilization, and estimation and identification.
ESIF: Bring Us Your Challenges
DOE Office of Scientific and Technical Information (OSTI.GOV)
2016-08-01
This brochure highlights the Energy Systems Integration Facility (ESIF) -- the United States' premier lab focused on energy systems research, development, and demonstration (RD&D). Topics covered include an overview of Energy Systems Integration, research focus areas, RD&D tools unique to the ESIF, and information on how to partner with NREL at the ESIF.
Handbook for Metric Usage (First Edition).
ERIC Educational Resources Information Center
American Home Economics Association, Washington, DC.
Guidelines for changing to the metric system of measurement with regard to all phases of home economics are presented in this handbook. Topics covered include the following: (1) history of the metric system, (2) the International System of Units (SI): derived units of length, mass, time, and electric current; temperature; luminous intensity;…
NASA Technical Reports Server (NTRS)
Wolfe, Jean; Bauer, Jeff; Bixby, C.J.; Lauderdale, Todd; Shively, Jay; Griner, James; Hayhurst, Kelly
2010-01-01
Topics discussed include: Aeronautics Research Mission Directorate Integrated Systems Research Program (ISRP) and UAS Integration in the NAS Project; UAS Integration into the NAS Project; Separation Assurance and Collision Avoidance; Pilot Aircraft Interface Objectives/Rationale; Communication; Certification; and Integrated Tests and Evaluations.
Automation of Space Station module power management and distribution system
NASA Technical Reports Server (NTRS)
Bechtel, Robert; Weeks, Dave; Walls, Bryan
1990-01-01
Viewgraphs on automation of space station module (SSM) power management and distribution (PMAD) system are presented. Topics covered include: reasons for power system automation; SSM/PMAD approach to automation; SSM/PMAD test bed; SSM/PMAD topology; functional partitioning; SSM/PMAD control; rack level autonomy; FRAMES AI system; and future technology needs for power system automation.
NASA Tech Briefs, January 1989. Volume 13, No. 1
NASA Technical Reports Server (NTRS)
1989-01-01
Topics include: Electronic Components & and Circuits. Electronic Systems, A Physical Sciences, Materials, Computer Programs, Mechanics, Machinery, Fabrication Technology, Mathematics and Information Sciences, and Life Sciences.
NASA Tech Briefs, June 1993. Volume 17, No. 6
NASA Technical Reports Server (NTRS)
1993-01-01
Topics include: Imaging Technology: Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, February 1993. Volume 17, No. 2
NASA Technical Reports Server (NTRS)
1993-01-01
Topics include: Communication Technology; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, April 1992. Volume 16, No. 4
NASA Technical Reports Server (NTRS)
1992-01-01
Topics covered include: New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences.
Summary of compliant and multi-arm control at NASA. Langley Research Center
NASA Technical Reports Server (NTRS)
Harrison, Fenton W.
1992-01-01
The topics are presented in viewgraph form and include the: single arm system, single arm axis system, single arm control systems, single arm hand controller axis system, single arm position axis system, single arm vision axis system, single arm force axis system, multi-arm system, multi-arm axis system, and the dual arm hand control axis system with control signals.
Eczema therapeutics in children: what do the clinical trials say?
Leung, Theresa N H; Hon, K L
2015-06-01
Eczema or atopic dermatitis is a common childhood atopic disease associated with chronicity and impaired quality of life. As there is no cure for the disease, treatment relies on topical and systemic anti-allergic or immunomodulating therapies. Topical corticosteroid, macrolide immunosuppressants, and oral immunomodulating drugs for recalcitrant disease have been the mainstay of therapy. Management of atopic dermatitis must consider the individual symptomatic variability of the disease. Basic therapy is focused on patient/family education, hydrating topical treatment, and avoidance of specific and non-specific provocative factors. Anti-inflammatory treatment based on topical glucocorticosteroids and topical calcineurin inhibitors is used for exacerbation management and more recently in selective cases for proactive therapy. Systemic immunosuppressive treatment is an option for severe refractory cases. Microbial colonisation and superinfection may induce disease exacerbation and justify additional antimicrobial treatment. Adjuvant therapy includes ultraviolet (UV) irradiation preferably with UVA1 or narrowband UVB. Dietary recommendations should be specific and given only when food allergy is confirmed. Allergen-specific immunotherapy against aeroallergens may be useful in selected cases. Parallel use of traditional and proprietary topical and herbal medicine has also been popular in China and many cities in Asia. Complementary and alternative medicine may have a place but evidence-based data are lacking.
Geothermal energy systems plan for Boise City
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1979-01-01
This is a plan for development of a downtown Boise geothermal district space heating system incorporating legal, engineering, organizational, geological, and economic requirements. Topics covered include: resource characteristics, system design and feasibility, economic feasibility, legal overview, organizational alternatives, and conservation. Included in appendices are: property ownership patterns on the Boise Front, existing hot well data, legal briefs, environmental data, decision point communications, typical building heating system retrofit schematics, and background assumptions and data for cost summary. (MHR)
ASM Conference on Prokaryotic Development
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kaplan, H. B.
2005-07-13
Support was provided by DOE for the 2nd ASM Conference on Prokaryotic Development. The final conference program and abstracts book is attached. The conference presentations are organized around topics that are central to the current research areas in prokaryotic development. The program starts with topics that involve relatively simple models systems and ends with systems that are more complex. The topics are: i) the cell cycle, ii) the cytoskeleton, iii) morphogenesis, iv) developmental transcription, v) signaling, vi) multicellularity, and vii) developmental diversity and symbiosis. The best-studied prokaryotic development model systems will be highlighted at the conference through research presentations bymore » leaders in the field. Many of these systems are also model systems of relevance to the DOE mission including carbon sequestration (Bradyrizobium, Synechococcus), energy production (Anabaena, Rhodobacter) and bioremediation (Caulobacter, Mesorhizobium). In addition, many of the highlighted organisms have important practical applications; the actinomycetes and myxobacteria produce antimicrobials that are of commercial interest. It is certain that the cutting-edge science presented at the conference will be applicable to the large group of bacteria relevant to the DOE mission.« less
Transdermal patches: history, development and pharmacology.
Pastore, Michael N; Kalia, Yogeshvar N; Horstmann, Michael; Roberts, Michael S
2015-05-01
Transdermal patches are now widely used as cosmetic, topical and transdermal delivery systems. These patches represent a key outcome from the growth in skin science, technology and expertise developed through trial and error, clinical observation and evidence-based studies that date back to the first existing human records. This review begins with the earliest topical therapies and traces topical delivery to the present-day transdermal patches, describing along the way the initial trials, devices and drug delivery systems that underpin current transdermal patches and their actives. This is followed by consideration of the evolution in the various patch designs and their limitations as well as requirements for actives to be used for transdermal delivery. The properties of and issues associated with the use of currently marketed products, such as variability, safety and regulatory aspects, are then described. The review concludes by examining future prospects for transdermal patches and drug delivery systems, such as the combination of active delivery systems with patches, minimally invasive microneedle patches and cutaneous solutions, including metered-dose systems. © 2015 The British Pharmacological Society.
NASA Tech Briefs, January 1992. Volume 16, No. 1
NASA Technical Reports Server (NTRS)
1992-01-01
Topics include: New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Fabrication; Mathematics and Information Sciences; Life Sciences;
Computer Sciences and Data Systems, volume 2
NASA Technical Reports Server (NTRS)
1987-01-01
Topics addressed include: data storage; information network architecture; VHSIC technology; fiber optics; laser applications; distributed processing; spaceborne optical disk controller; massively parallel processors; and advanced digital SAR processors.
NASA Tech Briefs, May 1992. Volume 16, No. 5
NASA Technical Reports Server (NTRS)
1992-01-01
Topics include: New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, July 1992. Volume 16, No. 7
NASA Technical Reports Server (NTRS)
1992-01-01
Topics include: New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, March 1992. Volume 16, No. 3
NASA Technical Reports Server (NTRS)
1992-01-01
Topics include: New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Technical Reports Server (NTRS)
Bai, S. Don
2000-01-01
Design, propellant selection, and launch assistance for advanced chemical propulsion system is discussed. Topics discussed include: rocket design, advance fuel and high energy density materials, launch assist, and criteria for fuel selection.
NASA Tech Briefs, September 1997. Volume 21, No. 9
NASA Technical Reports Server (NTRS)
1997-01-01
Topics include: Data Acquisition and Analysis; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Software; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences.
Wind Turbine Optimization with WISDEM
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dykes, Katherine L; Damiani, Rick R; Graf, Peter A
This presentation for the Fourth Wind Energy Systems Engineering Workshop explains the NREL wind energy systems engineering initiative-developed analysis platform and research capability to capture important system interactions to achieve a better understanding of how to improve system-level performance and achieve system-level cost reductions. Topics include Wind-Plant Integrated System Design and Engineering Model (WISDEM) and multidisciplinary design analysis and optimization.
The Evolution of Instructional Design Principles for Intelligent Computer-Assisted Instruction.
ERIC Educational Resources Information Center
Dede, Christopher; Swigger, Kathleen
1988-01-01
Discusses and compares the design and development of computer assisted instruction (CAI) and intelligent computer assisted instruction (ICAI). Topics discussed include instructional systems design (ISD), artificial intelligence, authoring languages, intelligent tutoring systems (ITS), qualitative models, and emerging issues in instructional…
Seventh symposium on systems analysis in forest resources; 1997 May 28-31; Traverse City, MI.
J. Michael Vasievich; Jeremy S. Fried; Larry A. Leefers
2000-01-01
This international symposium included presentations by representatives from government, academic, and private institutions. Topics covered management objectives; information systems: modeling, optimization, simulation and decision support techniques; spatial methods; timber supply; and economic and operational analyses.
Data systems and computer science space data systems: Onboard networking and testbeds
NASA Technical Reports Server (NTRS)
Dalton, Dan
1991-01-01
The technical objectives are to develop high-performance, space-qualifiable, onboard computing, storage, and networking technologies. The topics are presented in viewgraph form and include the following: justification; technology challenges; program description; and state-of-the-art assessment.
Production Systems. Laboratory Activities.
ERIC Educational Resources Information Center
Gallaway, Ann, Ed.
This production systems guide provides teachers with learning activities for secondary students. Introductory materials include an instructional planning outline and worksheet, an outline of essential elements, domains and objectives, a course description, and a content outline. The guide contains 30 modules on the following topics: production…
The 9th Aerospace Mechanisms Symposium
NASA Technical Reports Server (NTRS)
1975-01-01
Papers are presented dealing with performance and development of various spacecraft components, mechanical devices, and subsystems. Topics discussed include: manipulator arms, the Skylab Parasol, cooling system performance, extendable booms, magnetically suspended reaction wheels, the Skylab Trash Airlock, magnetometers, actuators, life support systems, and technology transfer.
Wind Shear radar program future plans
NASA Technical Reports Server (NTRS)
Robertson, Roy E.
1991-01-01
The status of the Windshear Radar Program at the Collins Air Transport Division of Rockwell International is given in viewgraph form. Topics covered include goals, modifications to the WXR-700 system, flight test plans, technical approaches, design considerations, system considerations, certification, and future plans.
Communication Systems. Laboratory Activities.
ERIC Educational Resources Information Center
Sutherland, Barbara, Ed.
This communication systems guide provides teachers with learning activities for secondary students. Introductory materials include an instructional planning outline and worksheet, an outline of essential elements, a list of objectives, a course description, and a content outline. The guide contains 32 modules on the following topics: story…
The Carnegie Mellon/Sirsi Corporation Alliance.
ERIC Educational Resources Information Center
Troll, Denise A.; Depellegrin, Tracey A.; Myers, Melanie D.
1999-01-01
Describes the relationship between Carnegie Mellon University libraries and Sirsi Corporation, their integrated library-management system vendor. Topics include Carnegie Mellon's expertise in library automation research and development; and three primary elements of the alliance: research, including user protocols, surveys, and focus groups;…
Aerospace Medicine and Biology. A continuing bibliography with indexes
NASA Technical Reports Server (NTRS)
1982-01-01
This bibliography lists 244 reports, articles, and other documents introduced into the NASA scientific and technical information system in February 1981. Aerospace medicine and aerobiology topics are included. Listings for physiological factors, astronaut performance, control theory, artificial intelligence, and cybernetics are included.
Technology Systems. Laboratory Activities.
ERIC Educational Resources Information Center
Brame, Ray; And Others
This guide contains 43 modules of laboratory activities for technology education courses. Each module includes an instructor's resource sheet and the student laboratory activity. Instructor's resource sheets include some or all of the following elements: module number, course title, activity topic, estimated time, essential elements, objectives,…
Content Management and the Future of Academic Libraries.
ERIC Educational Resources Information Center
Wu, Yuhfen Diana; Liu, Mengxiong
2001-01-01
Discusses Internet-based electronic content management in digital libraries and considers the future of academic libraries. Topics include digital technologies; content management systems; standards; bandwidth; security and privacy concerns; legal matters, including copyrights and ownership; lifecycle; and multilingual access and interface. (LRW)
Aerospace medicine and biology. A continuing bibliography with indexes
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1982-03-01
This bibliography lists 244 reports, articles, and other documents introduced into the NASA scientific and technical information system in February 1981. Aerospace medicine and aerobiology topics are included. Listings for physiological factors, astronaut performance, control theory, artificial intelligence, and cybernetics are included.
NASA Astrophysics Data System (ADS)
Sorg, H.
Among the topics discussed are: drift and scale factor tests on the SEL fiber gyro; integrated optical rate sensor development; and the beam geometry of a ring laser gyro in relation to its performance. Consideration is also given to: a fast filtering technique for measuring random walk in a laser gyro; vibratory gyroscopic sensors; a redundant strapdown reference for advanced aircraft flight control systems; and a low-cost piezoelectric rate/acceleration sensor. Additional topics include: an inertial guidance system for a Low-Earth-Orbit (LEO) vehicle; and signal disturbance effects in a strapdown northfinder.
Workshop report: US-China workshop on smart structures and smart systems
NASA Astrophysics Data System (ADS)
Tomizuka, Masayoshi
2006-03-01
A Joint U.S.-China workshop on the topic of Integrated Sensing Systems, Mechatronics and Smart Structures Technologies was held in Jinan, China in October 2005 to evaluate the current status of research and education in the topic areas in the United States and China, to identify critical and strategic research and educational issues of mutual interest, and to identify joint research projects and potential research teams for collaborative research activities. The workshop included a series of presentations by leading researchers and educators from the United States and China and group discussions on the workshop objectives.
NASA Technical Reports Server (NTRS)
1977-01-01
The microwave scanning beam landing system (MSBLS) is the primary position sensor of the Orbiter's navigation subsystem during the autoland phase of the flight. Portions of the system are discussed with special emphasis placed on potential problem areas as referenced to the Orbiter's mission. Topics discussed include system compatability, system accuracy, and expected RF signal levels. A block and flow diagram of MSBLS system operation is included with a list of special tests required to determine system performance.
Yong, Yi Lai; Tan, Loh Teng-Hern; Ming, Long Chiau; Chan, Kok-Gan; Lee, Learn-Han; Goh, Bey-Hing; Khan, Tahir Mehmood
2017-01-01
In particular, neuropathic pain is a major form of chronic pain. This type of pain results from dysfunction or lesions in the central and peripheral nervous system. Capsaicin has been traditionally utilized as a medicine to remedy pain. However, the effectiveness and safety of this practice is still elusive. Therefore, this systematic review aimed to investigate the effect of topical capsaicin as a pain-relieving agent that is frequently used in pain management. In brief, all the double-blinded, randomized placebo- or vehicle-controlled trials that were published in English addressing postherpetic neuralgia were included. Meta-analysis was performed using Revman® version 5.3. Upon application of the inclusion and exclusion criteria, only six trials fulfilled all the criteria and were included in the review for qualitative analysis. The difference in mean percentage change in numeric pain rating scale score ranges from -31 to -4.3. This demonstrated high efficacy of topical capsaicin application and implies that capsaicin could result in pain reduction. Furthermore, meta-analysis was performed on five of the included studies. All the results of studies are in favor of the treatment using capsaicin. The incidence of side effects from using topical capsaicin is consistently higher in all included studies, but the significance of safety data cannot be quantified due to a lack of p-values in the original studies. Nevertheless, topical capsaicin is a promising treatment option for specific patient groups or certain neuropathic pain conditions such as postherpetic neuralgia. PMID:28119613
Fukunishi, Yoshifumi; Mashimo, Tadaaki; Misoo, Kiyotaka; Wakabayashi, Yoshinori; Miyaki, Toshiaki; Ohta, Seiji; Nakamura, Mayu; Ikeda, Kazuyoshi
2016-01-01
Computer-aided drug design is still a state-of-the-art process in medicinal chemistry, and the main topics in this field have been extensively studied and well reviewed. These topics include compound databases, ligand-binding pocket prediction, protein-compound docking, virtual screening, target/off-target prediction, physical property prediction, molecular simulation and pharmacokinetics/pharmacodynamics (PK/PD) prediction. Message and Conclusion: However, there are also a number of secondary or miscellaneous topics that have been less well covered. For example, methods for synthesizing and predicting the synthetic accessibility (SA) of designed compounds are important in practical drug development, and hardware/software resources for performing the computations in computer-aided drug design are crucial. Cloud computing and general purpose graphics processing unit (GPGPU) computing have been used in virtual screening and molecular dynamics simulations. Not surprisingly, there is a growing demand for computer systems which combine these resources. In the present review, we summarize and discuss these various topics of drug design.
Fukunishi, Yoshifumi; Mashimo, Tadaaki; Misoo, Kiyotaka; Wakabayashi, Yoshinori; Miyaki, Toshiaki; Ohta, Seiji; Nakamura, Mayu; Ikeda, Kazuyoshi
2016-01-01
Abstract: Background Computer-aided drug design is still a state-of-the-art process in medicinal chemistry, and the main topics in this field have been extensively studied and well reviewed. These topics include compound databases, ligand-binding pocket prediction, protein-compound docking, virtual screening, target/off-target prediction, physical property prediction, molecular simulation and pharmacokinetics/pharmacodynamics (PK/PD) prediction. Message and Conclusion: However, there are also a number of secondary or miscellaneous topics that have been less well covered. For example, methods for synthesizing and predicting the synthetic accessibility (SA) of designed compounds are important in practical drug development, and hardware/software resources for performing the computations in computer-aided drug design are crucial. Cloud computing and general purpose graphics processing unit (GPGPU) computing have been used in virtual screening and molecular dynamics simulations. Not surprisingly, there is a growing demand for computer systems which combine these resources. In the present review, we summarize and discuss these various topics of drug design. PMID:27075578
LASER Tech Briefs, Winter 1994. Volume 2, No. 1
NASA Technical Reports Server (NTRS)
Schnirring, Bill (Editor)
1994-01-01
Topics include: Electronic Components and Circuits. Electronic Systems, Physical Sciences, Materials, Computer Programs, Mechanics, Machinery, Fabrication Technology, Mathematics and Information Sciences, Life Sciences, and Books and reports
NASA Tech Briefs, May 1993. Volume 17, No. 5
NASA Technical Reports Server (NTRS)
1993-01-01
Topics include: Advanced Composites and Plastics; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
Annual Review of Research Under the Joint Services Electronics Program.
1978-10-01
Electronic Science at Texas Tech University. Specific topics covered include fault analysis, Stochastic control and estimation, nonlinear control, multidimensional system theory , Optical noise, and pattern recognition.
LASER Tech Briefs, February 1995. Volume 3, No. 1
NASA Technical Reports Server (NTRS)
1995-01-01
Topics included in this issue of LASER Tech Briefs are: Electronic Components and Circuits. Electronic Systems, Physical Sciences, Materials, Mechanics, Fabrication, and Mathematics and Information Sciences, and
NASA Tech Briefs, February 1992. Volume 16, No. 2
NASA Technical Reports Server (NTRS)
1992-01-01
Topics covered include: New Product Development; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, Fall 1985. Volume 9, No. 3
NASA Technical Reports Server (NTRS)
1985-01-01
Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Life Sciences Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences.
NASA Tech Briefs, September 2000. Volume 24, No. 9
NASA Technical Reports Server (NTRS)
2000-01-01
Topics include: Sensors; Test and Measurement; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Bio-Medical; semiconductors/ICs; Books and Reports.
NASA Tech Briefs, July 1993. Volume 17, No. 7
NASA Technical Reports Server (NTRS)
1993-01-01
Topics include: Data Acquisition and Analysis: Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, June 1992. Volume 16, No. 6
NASA Technical Reports Server (NTRS)
1992-01-01
Topics covered include: New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, January 1995. Volume 19, No. 1
NASA Technical Reports Server (NTRS)
1995-01-01
Topics include: Sensors; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences; Books and Reports
NASA Tech Briefs, April 1988. Volume 12, No. 4
NASA Technical Reports Server (NTRS)
1988-01-01
Topics include: New Product Ideas; NASA TU Services; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences.
Next Generation Internet Overview
NASA Technical Reports Server (NTRS)
desJardins, R.
1998-01-01
Various issues associated with next generation Internet are presented in viewgraph form. Specific topics include: 1) Internet architecture; 2) NASA's advanced networking; 3) Internet capability, capacity and applications; and 4) Systems engineering.
NASA Tech Briefs, July 1989. Volume 13, No. 7
NASA Technical Reports Server (NTRS)
1989-01-01
Topics include New Product Ideas; NASA TU Services; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials;;Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences.
Update on the management of rosacea
Weinkle, Allison P; Doktor, Vladyslava; Emer, Jason
2015-01-01
Refining diagnostic criteria has identified key characteristics differentiating rosacea, a chronic skin disorder, from other common cutaneous inflammatory conditions. The current classification system developed by the National Rosacea Society Expert Committee consists of erythematotelangiectatic, papulopustular, phymatous, and ocular subtypes. Each subtype stands as a unique entity among a spectrum, with characteristic symptoms and physical findings, along with an intricate pathophysiology. The main treatment modalities for rosacea include topical, systemic, laser, and light therapies. Topical brimonidine tartrate gel and calcineurin inhibitors are at the forefront of topical therapies, alone or in combination with traditional therapies such as topical metronidazole or azelaic acid and oral tetracyclines or isotretinoin. Vascular laser and intense pulsed light therapies are beneficial for the erythema and telangiectasia, as well as the symptoms (itching, burning, pain, stinging, swelling) of rosacea. Injectable botulinum toxin, topical ivermectin, and microsecond long-pulsed neodymium-yttrium aluminum garnet laser are emerging therapies that may prove to be extremely beneficial in the future. Once a debilitating disorder, rosacea has become a well known and manageable entity in the setting of numerous emerging therapeutic options. Herein, we describe the treatments currently available and give our opinions regarding emerging and combination therapies. PMID:25897253
The Telecommunications and Data Acquisition Report
NASA Technical Reports Server (NTRS)
Posner, E. C. (Editor)
1990-01-01
Archival reports on developments in programs managed by the JPL Office of Telecommunications and Data Acquisition (TDA) are provided. Topics covered include: DSN advanced systems (tracking and ground-based navigation; communications, spacecraft-ground; and station control and system technology) and DSN systems implementation (capabilities for existing projects; capabilities for new projects; TDA program management and analysis; and Goldstone solar system radar).
Space Propulsion Technology Program Overview
NASA Technical Reports Server (NTRS)
Escher, William J. D.
1991-01-01
The topics presented are covered in viewgraph form. Focused program elements are: (1) transportation systems, which include earth-to-orbit propulsion, commercial vehicle propulsion, auxiliary propulsion, advanced cryogenic engines, cryogenic fluid systems, nuclear thermal propulsion, and nuclear electric propulsion; (2) space platforms, which include spacecraft on-board propulsion, and station keeping propulsion; and (3) technology flight experiments, which include cryogenic orbital N2 experiment (CONE), SEPS flight experiment, and cryogenic orbital H2 experiment (COHE).
Pixels, people, perception, pet peeves, and possibilities: a look at displays
NASA Astrophysics Data System (ADS)
Task, H. Lee
2007-04-01
This year marks the 35 th anniversary of the Visually Coupled Systems symposium held at Brooks Air Force Base, San Antonio, Texas in November of 1972. This paper uses the proceedings of the 1972 VCS symposium as a guide to address several topics associated primarily with helmet-mounted displays, systems integration and the human-machine interface. Specific topics addressed include monocular and binocular helmet-mounted displays (HMDs), visor projection HMDs, color HMDs, system integration with aircraft windscreens, visual interface issues and others. In addition, this paper also addresses a few mysteries and irritations (pet peeves) collected over the past 35+ years of experience in the display and display related areas.
NASA Astrophysics Data System (ADS)
Fast, R. W.
The book presents a review of literature on superfluid helium, together with papers under the topics on heat and mass transfer in He II; applications of He II for cooling superconducting devices in space; heat transfer to liquid helium and liquid nitrogen; multilayer insulation; applications of superconductivity, including topics on magnets and other devices, magnet stability and coil protection, and cryogenic techniques; and refrigeration for electronics. Other topics discussed include refrigeration of superconducting systems; the expanders, cold compressors, and pumps for liquid helium; dilution refrigerators; magnetic refrigerators; pulse tube refrigerators; cryocoolers for space applications; properties of cryogenic fluids; cryogenic instrumentation; hyperconducting devices (cryogenic magnets); cryogenic applications in space science and technology and in transportation; and miscellaneous cryogenic techniques and applications.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
These proceedings of the 1981 annual meeting of the Committee on Hearing, Bioacoustics, and Biomechanics cover topics of emerging research in several areas of interest to the Committee. Topics covered include: hair cell function; transduction process of hair cells; speech synthesis; machine recognition of words; neuromagnetic analysis of sensory systems; tinnitus; tactile communication of speech; and biodynamic research at the Air Force Aerospace Medical Research Laboratory.
Technologies for ECLSS Evolution
NASA Technical Reports Server (NTRS)
Diamant, Bryce L.
1990-01-01
Viewgraphs and discussion on technologies for Environmental Control and Life Support System (ECLSS) evolution are presented. Topics covered include: atmosphere revitalization including CO2 removal, CO2 reduction, O2 generation, and trace contaminant control; water recovery and management including urine processing, hygiene water processing, and potable water processing; and waste management. ECLSS technology schematics, process diagrams, and fluid interfaces are included.
Digital avionics systems - Principles and practices (2nd revised and enlarged edition)
NASA Technical Reports Server (NTRS)
Spitzer, Cary R.
1993-01-01
The state of the art in digital avionics systems is surveyed. The general topics addressed include: establishing avionics system requirements; avionics systems essentials in data bases, crew interfaces, and power; fault tolerance, maintainability, and reliability; architectures; packaging and fitting the system into the aircraft; hardware assessment and validation; software design, assessment, and validation; determining the costs of avionics.
Proceedings of the international conference on cybernetics and societ
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1985-01-01
This book presents the papers given at a conference on artificial intelligence, expert systems and knowledge bases. Topics considered at the conference included automating expert system development, modeling expert systems, causal maps, data covariances, robot vision, image processing, multiprocessors, parallel processing, VLSI structures, man-machine systems, human factors engineering, cognitive decision analysis, natural language, computerized control systems, and cybernetics.
NASA Technical Reports Server (NTRS)
Maluf, David A.; Koga, Dennis (Technical Monitor)
2002-01-01
This presentation discuss NASA's proposed NETMARK knowledge management tool which aims 'to control and interoperate with every block in a document, email, spreadsheet, power point, database, etc. across the lifecycle'. Topics covered include: system software requirements and hardware requirements, seamless information systems, computer architecture issues, and potential benefits to NETMARK users.
Issues in NASA Program and Project Management: Focus on Project Planning and Scheduling
NASA Technical Reports Server (NTRS)
Hoffman, Edward J. (Editor); Lawbaugh, William M. (Editor)
1997-01-01
Topics addressed include: Planning and scheduling training for working project teams at NASA, overview of project planning and scheduling workshops, project planning at NASA, new approaches to systems engineering, software reliability assessment, and software reuse in wind tunnel control systems.
Computational Methods for Structural Mechanics and Dynamics
NASA Technical Reports Server (NTRS)
Stroud, W. Jefferson (Editor); Housner, Jerrold M. (Editor); Tanner, John A. (Editor); Hayduk, Robert J. (Editor)
1989-01-01
Topics addressed include: transient dynamics; transient finite element method; transient analysis in impact and crash dynamic studies; multibody computer codes; dynamic analysis of space structures; multibody mechanics and manipulators; spatial and coplanar linkage systems; flexible body simulation; multibody dynamics; dynamical systems; and nonlinear characteristics of joints.
NASA Technical Reports Server (NTRS)
Erzberger, Heinz
2002-01-01
A general overview of the Advanced Airspace Concept (AAC) is presented. The topics include: 1) Limitations of the existing system; 2) The Advanced Airspace Concept; 3) Candidate architecture for the AAC; 4) Separation assurance and conflict avoidance system (TSAFE); and 5) Ground-Air Interactions. This paper is in viewgraph form.
A Labyrinth of the Wide World.
ERIC Educational Resources Information Center
Plater, William M.
1995-01-01
Discusses the design of the University Library at Indiana University, Purdue University Indianapolis. Topics include storage capacity; workstations; the user-friendly multimedia network information system; on- and off-campus connections to the system; the Center on Teaching and Learning; librarians' collaboration with faculty; and the Copyright…
Computer Page: Computer Studies for All--A Wider Approach
ERIC Educational Resources Information Center
Edens, A. J.
1975-01-01
An approach to teaching children aged 12 through 14 a substantial course about computers is described. Topics covered include simple algorithms, information and communication, man-machine communication, the concept of a system, the definition of a system, and the use of files. (SD)
Design and Implementation of a Tool for Teaching Programming.
ERIC Educational Resources Information Center
Goktepe, Mesut; And Others
1989-01-01
Discussion of the use of computers in education focuses on a graphics-based system for teaching the Pascal programing language for problem solving. Topics discussed include user interface; notification based systems; communication processes; object oriented programing; workstations; graphics architecture; and flowcharts. (18 references) (LRW)
Hitlerism and the German Universities.
ERIC Educational Resources Information Center
Neuriter, Paul R.
1999-01-01
An author who comes from the German higher education system offers insights into how it differs from the American higher education system and how certain undesirable characteristics may be avoided in the United States. Topics discussed include student independence, lack of extracurricular activities and campus community, tendency toward…
Trickling Filters. Student Manual. Biological Treatment Process Control.
ERIC Educational Resources Information Center
Richwine, Reynold D.
The textual material for a unit on trickling filters is presented in this student manual. Topic areas discussed include: (1) trickling filter process components (preliminary treatment, media, underdrain system, distribution system, ventilation, and secondary clarifier); (2) operational modes (standard rate filters, high rate filters, roughing…
Opportunities for electric utilities in telecommunications
DOE Office of Scientific and Technical Information (OSTI.GOV)
Meehan, C.M.
1994-11-01
This article examines the opportunities for utility participation in the telecommunications market on private microwave systems and hybrid microwave and fiber systems. The topics of the article include entering the market, national information infrastructure, business opportunities and considerations, levels of participation in telecommunications market, and regulatory objectives.
Optimizing Battery Usage and Management for Long Life
DOE Office of Scientific and Technical Information (OSTI.GOV)
Smith, Kandler; Shi, Ying; Wood, Eric
2016-06-16
This presentation discusses the impact of system design factors on battery aging and end of life. Topics include sizing of the SOC operating window, cell balancing and thermal management systems and their value in reducing pack degradation rates and cell imbalance growth over lifetime.
NASA Technical Reports Server (NTRS)
Pavel, M.
1993-01-01
The topics covered include the following: a system overview of the basic components of a system designed to improve the ability of a pilot to fly through low-visibility conditions such as fog; the role of visual sciences; fusion issues; sensor characterization; sources of information; image processing; and image fusion.
ERIC Educational Resources Information Center
Silver, George A.
1979-01-01
The comprehensive medical care system being utilized in China is described. Topics discussed include: the availability of medical care, training of physicians, medical care costs, and the political and social implications of the Chinese system. Lessons the United States can learn from the Chinese experience are presented. (BT)
Dutch Research on Knowledge-Based Instructional Systems: Introduction to the Special Issue.
ERIC Educational Resources Information Center
van Merrienboer, Jeroen J. G.
1994-01-01
Provides an overview of this issue that reviews Dutch research concerning knowledge-based instructional systems. Topics discussed include experimental research, conceptual models, design considerations, and guidelines; the design of student diagnostic modules, instructional modules, and interface modules; second-language teaching; intelligent…
State Analysis: A Control Architecture View of Systems Engineering
NASA Technical Reports Server (NTRS)
Rasmussen, Robert D.
2005-01-01
A viewgraph presentation on the state analysis process is shown. The topics include: 1) Issues with growing complexity; 2) Limits of common practice; 3) Exploiting a control point of view; 4) A glimpse at the State Analysis process; 5) Synergy with model-based systems engineering; and 6) Bridging the systems to software gap.
Aerospace medicine and biology: A continuing bibliography with indexes (supplement 383)
NASA Technical Reports Server (NTRS)
1994-01-01
This bibliography lists 100 reports, articles, and other documents introduced into the NASA Scientific and Technical Information System during Nov. 1992. Subject coverage includes the following topics: aerospace medicine and physiology, life support systems and man/system technology, protective clothing, exobiology and extraterrestrial life, planetary biology, and flight crew behavior and performance.
Delta nitrogen tetroxide fueling operations
NASA Technical Reports Server (NTRS)
Grigsby, R. B.; Cross, T. M.; Rucci, T. D.
1978-01-01
The development of the Delta second stage nitrogen tetroxide fueling system is briefly summarized. The nitrogen tetroxide fueling system and the equipment used to protect the spacecraft environment from the toxic nitrogen tetroxide fumes are described. Topics covered include: the nitrogen tetroxide transfer system; loading operations; safety precautions; and chemical treatment of all toxic vapors.
NASA Technical Reports Server (NTRS)
Grantier, David
2003-01-01
This paper presents viewgraphs on the development of the Weather Accident Prevention (WxAP) System architecture and Concept of Operation (CONOPS) activities. The topics include: 1) Background Information on System Architecture/CONOPS Activity; 2) Activity Work in Progress; and 3) Anticipated By-Products.
Models and techniques for evaluating the effectiveness of aircraft computing systems
NASA Technical Reports Server (NTRS)
Meyer, J. F.
1978-01-01
Progress in the development of system models and techniques for the formulation and evaluation of aircraft computer system effectiveness is reported. Topics covered include: analysis of functional dependence: a prototype software package, METAPHOR, developed to aid the evaluation of performability; and a comprehensive performability modeling and evaluation exercise involving the SIFT computer.
NASA Technical Reports Server (NTRS)
1990-01-01
A brief but comprehensive review is given of the technical accomplishments of the NASA Lewis Research Center during the past year. Topics covered include instrumentation and controls technology; internal fluid dynamics; aerospace materials, structures, propulsion, and electronics; space flight systems; cryogenic fluids; Space Station Freedom systems engineering, photovoltaic power module, electrical systems, and operations; and engineering and computational support.
Personal Approaches to Stress Reduction: A Workshop.
ERIC Educational Resources Information Center
Remer, Rory
1984-01-01
Seven topic areas which may be variously combined to comprise a workshop in personal stress reduction are outlined. They include definitions and types of stress, life style planning, nutrition, exercise, networking/social support system, relaxation and other trophotropic interventions, and communication skills. Suggestions are included for…
Building a DAM To Last: Archiving Digital Assets.
ERIC Educational Resources Information Center
Zeichick, Alan
2003-01-01
Discusses archiving digital information and the need for organizations to develop policies regarding digital asset management (DAM) and storage. Topics include determining the value of digital assets; formats of digital information; use of stored information; and system architecture, including hardware and asset management software. (LRW)
Information in the Water and Sanitation Sector.
ERIC Educational Resources Information Center
Rodda, John C.; And Others
1994-01-01
Includes 17 articles on aspects of collecting, managing, and disseminating data about the world's water supply and use. Topics addressed include United Nations agencies involved with water resources; management information systems; providing information needed by water resources professionals; and the role of regional organizations in providing…
ERIC Educational Resources Information Center
McDonald's Corp., Oak Brook, IL.
One of five McDonald's Action Packs, this learning package introduces intermediate grade students to basic economic concepts. The fourteen activities include the topics of consumption (4 activities), production (5), the market system (3), a pretest, and a posttest. Specific titles under consumption include The Wonderful Treasure Tree (introduction…
Making Our Buildings Safer: Security Management and Equipment Issues.
ERIC Educational Resources Information Center
Clark, James H.
1997-01-01
Discusses three major components of library security: physical security of the environment; operating procedures for library staff, the public, and security personnel; and a contract security force (or campus security in academic institutions.) Topics include risk management; maintenance; appropriate technology, including security systems and…
High Flight. Aerospace Activities, K-12.
ERIC Educational Resources Information Center
Oklahoma State Dept. of Education, Oklahoma City.
Following discussions of Oklahoma aerospace history and the history of flight, interdisciplinary aerospace activities are presented. Each activity includes title, concept fostered, purpose, list of materials needed, and procedure(s). Topics include planets, the solar system, rockets, airplanes, air travel, space exploration, principles of flight,…
NASA Tech Briefs, Spring 1976. Volume 1, No. 1
NASA Technical Reports Server (NTRS)
1976-01-01
Topics covered include : Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Life Sciences; Mechanics; Machinery; Fabrication Technology; and Mathematics and Information Sciences. Also included are NEW PRODUCT IDEAS: A summary of selected innovations of value to manufacturers for the development of new products.
Astronomical Resources: Astronomy Books of 1986--The Nontechnical List.
ERIC Educational Resources Information Center
Mercury, 1987
1987-01-01
Provides the results of an annual review of nontechnical astronomy books written for readers without extensive background in science or mathematics. Includes reviews of books on topics including amateur astronomy, comets, computers, cosmology, galaxies, pseudoscience, the solar system, space exploration, stellar evolution, telescopes and…
Tire safety : everything rides on it
DOT National Transportation Integrated Search
2008-01-01
This booklet presents a comprehensive overview of tire safety, including information on the following topics: basic tire maintenance; Uniform Tire Quality Grading System; fundamental characteristics of tires; and tire safety tips.
NASA Tech Briefs, August 1998. Volume 22, No. 8
NASA Technical Reports Server (NTRS)
1998-01-01
Topics include: special coverage of medical design, electronic components and circuits, electronic systems, software, materials, mechanics, machinery/automation, physical sciences, and a special section of Photonics Tech Briefs.
NASA Tech Briefs, July 2001. Volume 25, No. 7
NASA Technical Reports Server (NTRS)
2001-01-01
Topics include: special coverage sections on Data Acquisition, and sections on electronic components and systems, software, mechanics, machinery/automation, biomedical and a special section of Photonics Tech Briefs.
NASA Tech Briefs, August 1993. Volume 17, No. 8
NASA Technical Reports Server (NTRS)
1993-01-01
Topics include: Computer Graphics; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences; Books and Reports.
NASA Tech Briefs, September 1993. Volume 17, No. 9
NASA Technical Reports Server (NTRS)
1993-01-01
Topics include: Microelectronics; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences; Life Sciences; Books and Reports.
NASA Tech Briefs, September 1999. Volume 23, No. 9
NASA Technical Reports Server (NTRS)
1999-01-01
Topics discussed include: Computer-Aided Design and Engineering; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences;
NASA Tech Briefs, Winter 1985. Volume 9, No. 4
NASA Technical Reports Server (NTRS)
1985-01-01
Topics covered include: NASA TU Services; New Product Ideas; Electronic Components and Circuits;Electronic Systems; Physical Sciences; Materials; Life Sciences; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences.
NASA Tech Briefs, March 1993. Volume 17, No. 3
NASA Technical Reports Server (NTRS)
1993-01-01
Topics include: Computer-Aided Design and Engineering; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences;
NASA Tech Briefs, January 1994. Volume 18, No. 1
NASA Technical Reports Server (NTRS)
1994-01-01
Topics include: Communications Technology; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences; Books and Reports.
NASA Tech Briefs, January/February 1986. Volume 10, No. 1
NASA Technical Reports Server (NTRS)
1986-01-01
Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Life Sciences; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences.
Treatment of Annular Elastolytic Giant Cell Granuloma With Topical Tretinoin.
Wagenseller, Aubrey; Larocca, Cecilia; Vashi, Neelam A
2017-07-01
Annular elastolytic giant cell granuloma, also known as actinic granuloma, is a rare skin condition with a chronic course that is often resistant to treatment. Literature is sparse, and only a handful of case reports are available to guide treatment decisions. Typical first line treatment options include topical and intralesional steroids, topical pimecrolimus, and cryotherapy. Resistant cases have been treated with cyclosporine, systemic steroids, antimalarials, and oral retinoids. In particular, acitretin and isotretinoin have shown success in three cases. However, these medications can have side effects and require frequent lab monitoring. We present a case of a 47-year-old woman with bilateral forearm lesions consistent with annular elastolytic giant cell granuloma who was successfully treated with topical tretinoin.
J Drugs Dermatol. 2017;16(7):699-700.
.Topical oxygen as an adjunct to wound healing: a clinical case series.
Kalliainen, Loree K.; Gordillo, Gayle M.; Schlanger, Richard; Sen, Chandan K.
2003-01-01
BACKGROUND: Disrupted vasculature and high energy-demand to support processing and regeneration of wounded tissue are typical characteristics of a wound site. Oxygen delivery is a critical element for the healing of wounds. Clinical experience with adjunctive hyperbaric oxygen therapy in the treatment of chronic wounds have shown that wound hyperoxia increases wound granulation tissue formation and accelerates wound contraction and secondary closure. Nevertheless, the physiologic basis for this modality remains largely unknown. Also, systemic hyperbaric oxygen therapy is associated with risks related to oxygen toxicity. Topical oxygen therapy represents a less explored modality in wound care. The advantages of topical oxygen therapy include low cost, lack of systemic oxygen toxicity, and the ability to receive treatment at home, making the benefits of oxygen therapy available to a much larger population of patients. MATERIALS AND METHODS: Over 9 months, seven surgeons treated 58 wounds in 32 patients with topical oxygen with follow-up ranging from 1 to 8 months. The data presented herein is a retrospective analysis of the results we have achieved using topical oxygen on complex wounds. RESULTS: Thirty-eight wounds in 15 patients healed while on topical oxygen. An additional five wounds in five patients had preoperative oxygen therapy; all wounds initially healed postoperatively. In two patients, wounds recurred post-healing. In ten wounds, topical oxygen had no effect; and two of those patients went on to require limb amputation. There were no complications attributable to topical oxygen. Three patients died during therapy and one died in the first postoperative month from underlying medical problems. Two patients were lost to follow-up. CONCLUSIONS: In this case series, topical oxygen had no detrimental effects on wounds and showed beneficial indications in promoting wound healing.
Planning Systems for Distributed Operations
NASA Technical Reports Server (NTRS)
Maxwell, Theresa G.
2002-01-01
This viewgraph representation presents an overview of the mission planning process involving distributed operations (such as the International Space Station (ISS)) and the computer hardware and software systems needed to support such an effort. Topics considered include: evolution of distributed planning systems, ISS distributed planning, the Payload Planning System (PPS), future developments in distributed planning systems, Request Oriented Scheduling Engine (ROSE) and Next Generation distributed planning systems.
NASA Tech Briefs, September 1988. Volume 12, No. 8
NASA Technical Reports Server (NTRS)
1988-01-01
Topics include: New Product Ideas; NASA TU Services; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
Orion Passive Thermal: Control Overview
NASA Technical Reports Server (NTRS)
Alvarez-Hermandez, Angel; Miller, Stephen W.
2009-01-01
A general overview of the NASA Orion Passive Thermal Control System (PTCS) is presented. The topics include: 1) Orion in CxP Hierarchy; 2) General Orion Description/Orientation; and 3) Orion PTCS Overview.
LASER Tech Briefs, Fall 1994. Volume 2, No. 4
NASA Technical Reports Server (NTRS)
1994-01-01
Topics in this issue of LASER Tech briefs include: Electronic Components and Circuits. Electronic Systems, Physical Sciences, Materials, Computer Programs, Fabrication Technology, Mathematics and Information Sciences, and Life Sciences
NASA Tech Briefs, October 1988. Volume 12, No. 9
NASA Technical Reports Server (NTRS)
1988-01-01
Topics include: New Product Ideas; NASA TU Services; Electronic Components and Circuits; Electronic Systems; Physical Sciences Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, July 1991. Volume 15, No. 7
NASA Technical Reports Server (NTRS)
1991-01-01
Topics include: New Product Ideas; NASA TU Services; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
CTOL Transport Technology, 1978. [conferences
NASA Technical Reports Server (NTRS)
1978-01-01
Technology associated with advanced conventional takeoff and landing transport aircraft is discussed. Topics covered include: advanced aerodynamics and active controls; operations and safety; and advanced systems. Emphasis is placed on increased energy efficiency.
The Telecommunications and Data Acquisition Report
NASA Technical Reports Server (NTRS)
Posner, E. C. (Editor)
1987-01-01
Topics addressed include: tracking and ground-based navigation; communications, spacecraft-ground; station control and system technology; capabilities for existing projects; network upgrade and sustaining; mission interface and support; and Ka-band capabilities.
NASA Tech Briefs, March 1987. Volume 11, No. 3
NASA Technical Reports Server (NTRS)
1987-01-01
Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Fabrication Technology; Machinery; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, May 1987. Volume 11, No. 5
NASA Technical Reports Server (NTRS)
1987-01-01
Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Fabrication Technology; Machinery; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, October 1987. Volume 11, No. 9
NASA Technical Reports Server (NTRS)
1987-01-01
Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Fabrication Technology; Machinery; Mathematics and Information Sciences; Life Sciences.
ERIC Educational Resources Information Center
Broom, D. M.
1981-01-01
Discusses topics to aid in understanding animal behavior, including the value of the biological approach to psychology, functional systems, optimality and fitness, universality of environmental effects on behavior, and evolution of social behavior. (DS)
NASA Tech Briefs, June 1989. Volume 13, No. 6
NASA Technical Reports Server (NTRS)
1989-01-01
Topics include: New Product Ideas; NASA TU Services; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, February 1987. Volume 11, No. 2
NASA Technical Reports Server (NTRS)
1987-01-01
Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Fabrication Technology; Machinery; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, January 1987. Volume 11, No. 2
NASA Technical Reports Server (NTRS)
1987-01-01
Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Fabrication Technology; Machinery; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, July 1990. Volume 14, No. 7
NASA Technical Reports Server (NTRS)
1990-01-01
Topics include: New Product Ideas; NASA TU Services; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, April 1987. Volume 11, No. 4
NASA Technical Reports Server (NTRS)
1987-01-01
Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Fabrication Technology; Machinery; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, August 2002. Volume 26, No. 8
NASA Technical Reports Server (NTRS)
2002-01-01
Topics include: a technology focus on computers, electronic components and systems, software, materials, mechanics, machinery/automation, manufacturing, physical sciences, information sciences, book and reports, and Motion control Tech Briefs.
NASA Tech Briefs, September 1987. Volume 11, No. 8
NASA Technical Reports Server (NTRS)
1987-01-01
Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Fabrication Technology; Machinery; Mathematics and Information Sciences; Life Sciences.
Development of Shanghai satellite laser ranging station
NASA Technical Reports Server (NTRS)
Yang, Fu-Min; Tan, De-Tong; Xiao, Chi-Kun; Chen, Wan-Zhen; Zhang, J.-H.; Zhang, Z.-P.; Lu, Wen-Hu; Hu, Z.-Q.; Tang, W.-F.; Chen, J.-P.
1993-01-01
The topics covered include the following: improvement of the system hardware; upgrading of the software; the observation status; preliminary daylight tracking capability; testing the new type of laser; and future plans.
Advanced control technology and its potential for future transport aircraft
NASA Technical Reports Server (NTRS)
1976-01-01
The topics covered include fly by wire, digital control, control configured vehicles, applications to advanced flight vehicles, advanced propulsion control systems, and active control technology for transport aircraft.
NASA Tech Briefs, June 1994. Volume 18, No. 6
NASA Technical Reports Server (NTRS)
1994-01-01
Topics covered include: Microelectronics; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences; Life Sciences; Books and Reports
NASA Tech Briefs, August 1994. Volume 18, No. 8
NASA Technical Reports Server (NTRS)
1994-01-01
Topics covered include: Computer Hardware; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences; Books and Reports.
NASA Tech Briefs, October 1996. Volume 20, No. 10
NASA Technical Reports Server (NTRS)
1996-01-01
Topics covered include: Sensors; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences; Life Sciences; Books and Reports.
NASA Tech Briefs, June 1997. Volume 21, No. 6
NASA Technical Reports Server (NTRS)
1997-01-01
Topics include: Computer Hardware and Peripherals; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences; Books and Reports.
NASA Tech Briefs, June 1987. Volume 11, No. 6
NASA Technical Reports Server (NTRS)
1987-01-01
Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Fabrication Technology; Machinery; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, November 1999. Volume 23, No. 11
NASA Technical Reports Server (NTRS)
1999-01-01
Topics covered include: Computer-Aided Design and Engineering; Electronic Components and Circuits; Electronic Systems; Materials; Computer Programs; Mechanics; Machinery/Automation; Physical Sciences; Mathematics and Information Sciences; Books and Reports.
Graphite/Polyimide Composites. [conference on Composites for Advanced Space Transportation Systems
NASA Technical Reports Server (NTRS)
Dexter, H. B. (Editor); Davis, J. G., Jr. (Editor)
1979-01-01
Technology developed under the Composites for Advanced Space Transportation System Project is reported. Specific topics covered include fabrication, adhesives, test methods, structural integrity, design and analysis, advanced technology developments, high temperature polymer research, and the state of the art of graphite/polyimide composites.
Knowledge Management for the Analysis of Complex Experimentation.
ERIC Educational Resources Information Center
Maule, R.; Schacher, G.; Gallup, S.
2002-01-01
Describes a knowledge management system that was developed to help provide structure for dynamic and static data and to aid in the analysis of complex experimentation. Topics include quantitative and qualitative data; mining operations using artificial intelligence techniques; information architecture of the system; and transforming data into…
Materials for Space Exploration
NASA Technical Reports Server (NTRS)
Robertson, Luke B.; Williams, Martha
2010-01-01
Topics include a lab overview, testing and processing equipment, hemochromic hydrogen sensors, antimicrobial materials, wire system materials, CNT ink formulations, CNT ink dust screens, CNT ink printed circuitry, cryogenic materials development, fire and polymers, the importance of lighting, electric lighting systems, LED for plant growth, and carbon nanotube fiber filaments.
NASA Technical Reports Server (NTRS)
1986-01-01
The objective of the Workshop was to focus on the key technology area for 21st century spacecraft and the programs needed to facilitate technology development and validation. Topics addressed include: spacecraft systems; system development; structures and materials; thermal control; electrical power; telemetry, tracking, and control; data management; propulsion; and attitude control.
Developing Modern Information Systems and Services: Africa's Challenges for the Future.
ERIC Educational Resources Information Center
Chowdhury, G. G.
1996-01-01
Discusses the current state of information systems and services in Africa, examines future possibilities, and suggests areas for improvement. Topics include the lack of automation; CD-ROM databases for accessibility to information sources; developing low-cost electronic communication facilities; Internet connectivity; dependence on imported…
New Hampshire: The Automated Information System.
ERIC Educational Resources Information Center
Wiggin, Kendall F.
1996-01-01
Reviews statewide multitype library automation and connectivity initiatives in New Hampshire. Topics include an information system incorporating a union catalog, interlibrary loan, electronic mail, CD-ROM databases, and Internet access; state government information on the World Wide Web through the state library; OCLC FirstSearch access; and a…
Planning for the Introduction of the Metric System into Occupational Education Programs
ERIC Educational Resources Information Center
Low, A. W.
1974-01-01
A three-dimensional planning model for introducting the International System of Metric Units into Canadian occupational education curricula includes employment level, career area, and metric topics. A fourth dimension, time, is considered in four separate phases: familiarization, adoption, conversion, and compulsory usage.
Counseling Psychology in the Justice System.
ERIC Educational Resources Information Center
Binder, Arnold; Binder, Virginia L.
1983-01-01
Presents an overview of pscyhological counseling for offenders. The 12 articles of this special issue deal with counseling before trial, in prison, and after release and also crisis intervention for police officers. Other topics include the juvenile justice system, juvenile diversion, ethics, and the economics of service delivery. (JAC)
77 FR 1942 - Homeland Security Science and Technology Advisory Committee (HSSTAC)
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-12
... developments in systems engineering, cyber- security, knowledge management and how best to leverage related... contribution to a diverse range of science and technology topic areas (including chemical, biological, and... technology capabilities and needs, and the latest thinking in systems engineering), and their depth of...
Development of a solar-powered residential air conditioner. Program review
NASA Technical Reports Server (NTRS)
1975-01-01
Progress in the effort to develop a residential solar-powered air conditioning system is reported. The topics covered include the objectives, scope and status of the program. The results of state-of-art, design, and economic studies and component and system data are also presented.
Optimizing Battery Usage and Management for Long Life
DOE Office of Scientific and Technical Information (OSTI.GOV)
Smith, Kandler; Shi, Ying; Wood, Eric
2016-06-16
This presentation discusses the impact of system design factors on battery aging and end of life. Topics include sizing of the state-of-charge operating window, cell balancing, and thermal management systems and their value in reducing pack degradation rates and cell imbalance growth over lifetime.
Using Internet Technologies To Enhance Training.
ERIC Educational Resources Information Center
Pollock, Carl; Masters, Robert
1997-01-01
Describes how to use Internet technologies to create an intranet, or an online training database system, for improving company communications, effectiveness, and job performance. Topics include technology and performance; educating managers and key decision makers; creating a graphic model of the training system; and fitting into the existing…
The Future of Educational Technology Is Past.
ERIC Educational Resources Information Center
Mitchell, P. David
1989-01-01
Discusses the field of educational technology and the need for new perspectives on the processes of learning, teaching, and doing research. Topics discussed include the scope of education; goal-directed feedback; control system theory; cybernetics and general system research; self-instruction; and suggestions for future planning for educational…
The Molecules of the Immune System.
ERIC Educational Resources Information Center
Tonegawa, Susumu
1985-01-01
The immune system includes the most diverse proteins known because they are encoded by hundreds of scattered gene fragments which can be combined in millions or billions of ways. Events of immune response, binding of antigens, antibody structure, T-cell receptors, and other immunologically-oriented topics are discussed. (DH)
Optical memory system technology. Citations from the International Aerospace Abstracts data base
NASA Technical Reports Server (NTRS)
Zollars, G. F.
1980-01-01
Approximately 213 citations from the international literature which concern the development of the optical data storage system technology are presented. Topics covered include holographic computer storage devices, crystal, magneto, and electro-optics, imaging techniques, in addition to optical data processing and storage.
Current State of Nanomedicines in the Treatment of Topical Infectious Disorders.
Thakur, Kanika; Sharma, Gajanand; Singh, Bhupinder; Chhibber, Sanjay; Katare, Om Prakash
2018-05-28
Topical infections, involving a number of diseases such as impetigo, eczema, pustular acne, psoriasis and infected seborrheic dermatitis are one among the many challenges to health which stand out for their profound impact on human species. The treatment of topical infections has always been a difficult proposition because of the lack of efficacy of existing anti-infectives, longer period of treatment and yet incomplete recovery. The increasing emergence of antibiotic resistant bacterial strains like Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa undermine the need of development of new delivery systems to enhance the therapeutic efficacy of existing topical anti-infectives. The application of nanotechnology to medicine, or nanomedicine, is rapidly becoming a major driving force behind ongoing changes in the anti-infective field because of its interaction at the sub-atomic level with the skin tissue. The latter, in the current scenario, points towards vesicular carriers like liposomes, lipidic nanoparticles and silver nanoparticles etc. as the most promising drug delivery solutions for topical infection disorders. These have exhibited immense significance owing to their uniqueness to facilitate the interactions at interfaces with the barrier membranes. The present review summarizes the emerging efforts in combating topical infections particularly using nanomedicine based delivery systems as new tools to tackle the current challenges in treating infectious diseases. Besides, compiling various research reports, this article also includes formulation considerations, mechanisms of penetration and patents reported. Despite the new emerging technologies and delivery systems, efforts are still needed in the right direction to combat this global challenge. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
Building Earth's Largest Library: Driving into the Future.
ERIC Educational Resources Information Center
Coffman, Steve
1999-01-01
Examines the Amazon.com online bookstore as a blueprint for designing the world's largest library. Topics include selection; accessibility and convenience; quality of Web sites and search tools; personalized service; library collection development, including interlibrary loan; library catalogs and catalog records; a circulation system; costs;…
A novel lidocaine hydrochloride ophthalmic gel for topical ocular anesthesia
Shah, HR; Reichel, E; Busbee, BG
2010-01-01
Topical anesthetics play an important role in the practice of ophthalmology, both for procedures in the office and in the operating room. The need for safe, long-acting topical ocular anesthetic agents is ongoing, and has been highlighted by the increase of intravitreal administration of pharmacologic agents. Current practices for ocular anesthesia include subconjunctival injection of 2% aqueous lidocaine, topical 2% lidocaine drops and topical 0.5% tetracaine. Tetracaine is not yet FDA approved, and is associated with corneal epithelial toxicity and delayed epithelial healing after multiple administrations. Lidocaine jelly (2%) preparations have been reported to be beneficial in several systemic procedures, including those of the upper airway, dental, urogenital, and gastrointestinal. It has been theorized, and recent studies support the idea, that gel formulations of lidocaine may enhance anesthetic effect, and therefore be superior to anesthetic solutions for topical cataract surgery. The viscous nature of gel formulations is thought to lengthen contact time, resulting in better anesthesia at lower drug concentrations. Furthermore, several studies suggest that lidocaine is bactericidal and bacteriostatic, and may have a supplementary role in preventing and treating surgical site infections. Akten™, lidocaine 3.5% gel (Akorn, Buffalo Grove, IIlinois) was FDA approved for all ophthalmic procedures in October 2008. This gel is a preservative-free, lidocaine-based anesthetic gel consisting of 35 mg/mL of lidocaine hydrochloride. We describe the properties, including chemical structure, indications, evidence of support, use, adverse effects, and precautions, which we believe enable Akten to provide superior anesthesia, while minimizing side effects. PMID:22915870
Anand, P.; Bley, K.
2011-01-01
Summary Topical capsaicin formulations are used for pain management. Safety and modest efficacy of low-concentration capsaicin formulations, which require repeated daily self-administration, are supported by meta-analyses of numerous studies. A high-concentration capsaicin 8% patch (Qutenza™) was recently approved in the EU and USA. A single 60-min application in patients with neuropathic pain produced effective pain relief for up to 12 weeks. Advantages of the high-concentration capsaicin patch include longer duration of effect, patient compliance, and low risk for systemic effects or drug–drug interactions. The mechanism of action of topical capsaicin has been ascribed to depletion of substance P. However, experimental and clinical studies show that depletion of substance P from nociceptors is only a correlate of capsaicin treatment and has little, if any, causative role in pain relief. Rather, topical capsaicin acts in the skin to attenuate cutaneous hypersensitivity and reduce pain by a process best described as ‘defunctionalization’ of nociceptor fibres. Defunctionalization is due to a number of effects that include temporary loss of membrane potential, inability to transport neurotrophic factors leading to altered phenotype, and reversible retraction of epidermal and dermal nerve fibre terminals. Peripheral neuropathic hypersensitivity is mediated by diverse mechanisms, including altered expression of the capsaicin receptor TRPV1 or other key ion channels in affected or intact adjacent peripheral nociceptive nerve fibres, aberrant re-innervation, and collateral sprouting, all of which are defunctionalized by topical capsaicin. Evidence suggests that the utility of topical capsaicin may extend beyond painful peripheral neuropathies. PMID:21852280
1991-06-01
intensive systems, including the use of onboard digital computers. Topics include: measurements that are digital in origin, sampling, encoding, transmitting...Individuals charged with designing aircraft measuring systems to become better acquainted with new solutions to their requirements. This volume Is...concerned with aircraft measuring systems as related to flight test and flight research. Measure - ments that are digital in origin or that must be
Metal-Air Batteries: (Latest citations from the Aerospace Database)
NASA Technical Reports Server (NTRS)
1997-01-01
The bibliography contains citations concerning applications of metal-air batteries. Topics include systems that possess different practical energy densities at specific powers. Coverage includes the operation of air electrodes at different densities and performance results. The systems are used in electric vehicles as a cost-effective method to achieve reliability and efficiency. Zinc-air batteries are covered more thoroughly in a separate bibliography. (Contains 50-250 citations and includes a subject term index and title list.)
NASA Tech Briefs, February 1997. Volume 2, No. 2
NASA Technical Reports Server (NTRS)
1997-01-01
Topics include: Test and Measurement; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences; Life Sciences; Books and Reports
Research and technology of the Langley Research Center
NASA Technical Reports Server (NTRS)
1980-01-01
Descriptions of the research and technology activities at the Langley Research Center are given. Topics include laser development, aircraft design, aircraft engines, aerodynamics, remote sensing, space transportation systems, and composite materials.
NASA Tech Briefs, November 1988. Volume 12, No. 10
NASA Technical Reports Server (NTRS)
1988-01-01
Topics covered include: New Product Ideas; NASA TU Services; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, September/October 1986. Volume 10, No. 5
NASA Technical Reports Server (NTRS)
1986-01-01
Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Fabrication Technology; Machinery; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, April 1998. Volume 22, No. 4
NASA Technical Reports Server (NTRS)
1998-01-01
Topics include: special coverage on video and imaging, electronic components and circuits, electronic systems, physical sciences, materials, computer software, mechanics, machinery/automation, and a special section of Photonics Tech Briefs.
NASA Tech Briefs, May 1996. Volume 20, No. 5
NASA Technical Reports Server (NTRS)
1996-01-01
Topics include: Video and Imaging;Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences; Life Sciences; Books and Reports
NASA Tech Briefs, November/December 1986. Volume 10, No. 6
NASA Technical Reports Server (NTRS)
1986-01-01
Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Fabrication Technology; Machinery; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, October 1993. Volume 17, No. 10
NASA Technical Reports Server (NTRS)
1993-01-01
Topics include: Sensors; esign and Engineering; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication technology; Mathematics and Information Sciences; Life Sciences; Books and Reports.
NASA Tech Briefs, May 1994. Volume 18, No. 5
NASA Technical Reports Server (NTRS)
1994-01-01
Topics covered include: Robotics/Automation; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences; Life Sciences; Books and Reports.
NASA Tech Briefs, May/June 1986. Volume 10, No. 3
NASA Technical Reports Server (NTRS)
1986-01-01
Topics discussed include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, September 1990. Volume 14, No. 9
NASA Technical Reports Server (NTRS)
1990-01-01
Topics covered include: New Product Ideas; NASA TU Services; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, November/December 1987. Volume 11, No. 10
NASA Technical Reports Server (NTRS)
1987-01-01
Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Fabrication Technology; Machinery; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, February 1994. Volume 18, No. 2
NASA Technical Reports Server (NTRS)
1994-01-01
Topics covered include: Test and Measurement; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences; Books and Reports
Marshall Space Flight Center ECLSS technology activities
NASA Technical Reports Server (NTRS)
Wieland, Paul
1990-01-01
Viewgraphs on Environmental Control and Life Support System (ECLSS) technology activities are presented. Topics covered include: analytical development; ECLSS modeling approach; example of water reclamation modeling needs; and hardware development and testing.
NASA Tech Briefs, March 1988. Volume 12, No. 3
NASA Technical Reports Server (NTRS)
1988-01-01
Topics include: New Product Ideas; NASA TU Services; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; and Life Sciences.
NASA Tech Briefs, July 1996. Volume 20, No. 7
NASA Technical Reports Server (NTRS)
1996-01-01
Topics covered include: Mechanical Components; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences; Life Sciences; Books and Reports
NASA Tech Briefs, January 2000. Volume 24, No. 1
NASA Technical Reports Server (NTRS)
2000-01-01
Topics include: Data Acquisition; Computer-Aided Design and Engineering; Electronic Components and Circuits; Electronic Systems; Bio-Medical; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Information Sciences; Books and reports.
NASA Tech Briefs, July/August 1987. Volume 11, No. 7
NASA Technical Reports Server (NTRS)
1987-01-01
Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Fabrication Technology; Machinery; Mathematics and Information Sciences; Life Sciences.
Fuel system technology overview
NASA Technical Reports Server (NTRS)
Friedman, R.
1980-01-01
Fuel system research and technology studies are being conducted to investigate the correlations and interactions of aircraft fuel system design and environment with applicable characteristics of the fuel. Topics include: (1) analysis of in-flight fuel temperatures; (2) fuel systems for high freezing point fuels; (3) experimental study of low temperature pumpability; (4) full scale fuel tank simulation; and (5) rapid freezing point measurement.
ERIC Educational Resources Information Center
Humpherys, Sean LaMarc
2010-01-01
Given the increasing problem of fraud, crime, and national security threats, assessing credibility is a recurring research topic in Information Systems and in other disciplines. Decision support systems can help. But the success of the system depends on reliable cues that can distinguish deceptive/truthful behavior and on a proven classification…
Introduction to Fuzzy Set Theory
NASA Technical Reports Server (NTRS)
Kosko, Bart
1990-01-01
An introduction to fuzzy set theory is described. Topics covered include: neural networks and fuzzy systems; the dynamical systems approach to machine intelligence; intelligent behavior as adaptive model-free estimation; fuzziness versus probability; fuzzy sets; the entropy-subsethood theorem; adaptive fuzzy systems for backing up a truck-and-trailer; product-space clustering with differential competitive learning; and adaptive fuzzy system for target tracking.
NASA Technical Reports Server (NTRS)
Stubblefield, F. W. (Editor)
1987-01-01
Papers are presented on space, low-energy physics, and general nuclear science instrumentations. Topics discussed include data acquisition systems and circuits, nuclear medicine imaging and tomography, and nuclear radiation detectors. Consideration is given to high-energy physics instrumentation, reactor systems and safeguards, health physics instrumentation, and nuclear power systems.
Satellite Telemetry and Command using Big LEO Mobile Telecommunications Systems
NASA Technical Reports Server (NTRS)
Huegel, Fred
1998-01-01
Various issues associated with satellite telemetry and command using Big LEO mobile telecommunications systems are presented in viewgraph form. Specific topics include: 1) Commercial Satellite system overviews: Globalstar, ICO, and Iridium; 2) System capabilities and cost reduction; 3) Satellite constellations and contact limitations; 4) Capabilities of Globalstar, ICO and Iridium with emphasis on Globalstar; and 5) Flight transceiver issues and security.
Identification of linear system models and state estimators for controls
NASA Technical Reports Server (NTRS)
Chen, Chung-Wen
1992-01-01
The following paper is presented in viewgraph format and covers topics including: (1) linear state feedback control system; (2) Kalman filter state estimation; (3) relation between residual and stochastic part of output; (4) obtaining Kalman filter gain; (5) state estimation under unknown system model and unknown noises; and (6) relationship between filter Markov parameters and system Markov parameters.
González-Moles, M A; Scully, C
2005-04-01
Vesiculo-erosive diseases of the oral mucosa pose a major challenge in oral medicine, because they are chronic, painful, and interfere with the daily activities and quality of life of the patients, including disturbing eating, drinking, talking, and personal relationships. Many are autoimmune diseases, and corticosteroid therapy is currently central to their treatment. These diseases present with inflammation and alterations to epithelial integrity, through cell and/or humoral immunity-mediated attack on epithelial-connective tissue targets. Until recently, despite their serious adverse effects, it was necessary to prescribe systemic corticosteroids to control severe erosive oral diseases. Now, however, many of these diseases can be controlled by high-potency topical corticosteroids, which have proved to be highly efficacious and to cause fewer adverse effects compared with systemic corticosteroids. Nevertheless, although topical corticosteroids are still the most widely used drugs in the practice of oral medicine, the scientific body of evidence for their use in the oral cavity is virtually non-existent, and therefore many of the protocols followed are, of necessity, drawn from experience of their use in a dermatological setting. This review aims to set out the key aspects of the use of topical corticosteroids in oral medicine. The issues covered include the indications and basic rules for their use, the types of corticosteroids, the drug selection, and the specific formulations.
Steam plant startup and control in system restoration
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mello, F.P. de; Westcott, J.C.
1994-02-01
The IEEE Working Group on Power System Restoration developed a panel session for the Summer Power Meeting on July 14, 1992 on Special Considerations in Power System Restoration. One of the contributions to this session is presented in this paper dealing with aspects of steam plant startup and control in scenarios of system restoration. The topics addressed include the complexity of a steam plant, the contrast between normal plant startups and shutdowns and those following major system blackouts including the effects of plant design, automatic controls, bypass valving and operator training.
Large Space Antenna Systems Technology, 1984
NASA Technical Reports Server (NTRS)
Boyer, W. J. (Compiler)
1985-01-01
Papers are presented which provide a comprehensive review of space missions requiring large antenna systems and of the status of key technologies required to enable these missions. Topic areas include mission applications for large space antenna systems, large space antenna structural systems, materials and structures technology, structural dynamics and control technology, electromagnetics technology, large space antenna systems and the space station, and flight test and evaluation.
Review of Systemic Treatment Options for Adult Atopic Dermatitis.
Gooderham, Melinda; Lynde, Charles W; Papp, Kim; Bourcier, Marc; Guenther, Lyn; Gulliver, Wayne; Hong, Chih-Ho; Poulin, Yves; Sussman, Gordon; Vender, Ronald
Atopic dermatitis (AD) is a chronic, pruritic inflammatory skin disease resulting from defects in skin barrier and aberrant immune responses. AD significantly affects the quality of life. Not all patients respond to topical therapies, and often systemic therapy is required to control the disease. To review the treatment options for adult AD patients including those options for patients who do not respond adequately or have contraindications to oral systemic therapy. A working group of clinicians with experience managing AD was convened to review the current literature on treatment options for adult AD patients. This review is based on the best available evidence from a published systematic review and an additional literature search. Current treatments for AD are reviewed, including options for adult AD patients who do not respond or have contraindications to current systemic therapies. A new approach with targeted therapies is reviewed based on best available evidence. Many AD patients respond satisfactorily to topical or systemic treatments, but for those patients who do not respond or have contraindications, new biologic agents appear to be promising therapies.
Wireless Applications for Structural Monitoring of Inflatable Habitats
NASA Technical Reports Server (NTRS)
Miller, Glenn J.
2007-01-01
A viewgraph presentation on wireless applications for structural health monitoring of inflatable space structures is shown. The topics include: 1) Background; 2) REquirements; 3) Implementation; and 4) strucutral health monitoring system summary.
Proceedings of the Interagency Workshop on Lighter than Air Vehicles
NASA Technical Reports Server (NTRS)
Vittek, J. F., Jr. (Editor)
1975-01-01
Papers presented at the workshop are reported. Topics discussed include: economic and market analysis, technical and design considerations, manufacturing and operations, design concepts, airship applications, and unmanned and tethered systems.
NASA Tech Briefs, April 1997. Volume 21, No. 4
NASA Technical Reports Server (NTRS)
1997-01-01
Topics covered include: Video and Imaging; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences; Life Sciences; Books and Reports.
NASA Tech Briefs, March/April 1986. Volume 10, No. 2
NASA Technical Reports Server (NTRS)
1986-01-01
Topics covered include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences.
NASA Tech Briefs, December 1993. Volume 17, No. 12
NASA Technical Reports Server (NTRS)
1993-01-01
Topics covered include: High-Performance Computing; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences; Life Sciences; Books and Reports.
The 5th Annual NASA Spacecraft Control Laboratory Experiment (SCOLE) Workshop, part 2
NASA Technical Reports Server (NTRS)
Taylor, Lawrence W., Jr. (Compiler)
1990-01-01
A collection of papers from the workshop are presented. The topics addressed include: the modeling, systems identification, and control synthesis for the Spacecraft Control Laboratory Experiment (SCOLE) configuration.
NASA Tech Briefs, November 2001. Volume 25, No. 11
NASA Technical Reports Server (NTRS)
2001-01-01
Topics include: special coverage section on data acquisition, and sections on electronic components and systems, software, materials, machinery/automation, physical sciences, book and reports, and a special section of Photonics Tech Briefs.
NASA Tech Briefs, February 2000. Volume 24, No. 2
NASA Technical Reports Server (NTRS)
2000-01-01
Topics covered include: Test and Measurement; Computer-Aided Design and Engineering; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Bio-Medical; Mathematics and Information Sciences; Computers and Peripherals.
NASA Tech Briefs, April 2000. Volume 24, No. 4
NASA Technical Reports Server (NTRS)
2000-01-01
Topics covered include: Imaging/Video/Display Technology; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Bio-Medical; Test and Measurement; Mathematics and Information Sciences; Books and Reports.
NASA Tech Briefs, October 1997. Volume 21, No. 10
NASA Technical Reports Server (NTRS)
1997-01-01
Topics covered include: Sensors/Imaging; Mechanical Components; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Software; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences; Life Sciences; Books and Reports.
NASA Tech Briefs, June 2002. Volume 26, No. 6
NASA Technical Reports Server (NTRS)
2002-01-01
Topics include: a technology focus on data acquisition, electronic components and systems, software, materials, mechanics, machinery/automation, physical sciences, book and reports, motion control, and a special section of Photonics Tech Briefs.
Detection of faults and software reliability analysis
NASA Technical Reports Server (NTRS)
Knight, J. C.
1987-01-01
Specific topics briefly addressed include: the consistent comparison problem in N-version system; analytic models of comparison testing; fault tolerance through data diversity; and the relationship between failures caused by automatically seeded faults.
NASA Tech Briefs, January 1988. Volume 12, No. 1
NASA Technical Reports Server (NTRS)
1988-01-01
Topics covered include: New Product Ideas; NASA TU Services; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; and Life Sciences.
NASA Tech Briefs, March 1994. Volume 18, No. 3
NASA Technical Reports Server (NTRS)
1994-01-01
Topics include: Computer-Aided Design and Engineering; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences; Life Sciences; Books and Reports
NASA Tech Briefs, September 2001. Volume 25, No. 9
NASA Technical Reports Server (NTRS)
2001-01-01
Topics include: special coverage section on sensors, and sections on electronic components systems, software, materials, machinery/automation, manufacturing/fabrication, bio-medical, book and reports, and a special section of Photonics Tech Briefs.
Research in structures, structural dynamics and materials, 1989
NASA Technical Reports Server (NTRS)
Hunter, William F. (Compiler); Noor, Ahmed K. (Compiler)
1989-01-01
Topics addressed include: composite plates; buckling predictions; missile launch tube modeling; structural/control systems design; optimization of nonlinear R/C frames; error analysis for semi-analytic displacement; crack acoustic emission; and structural dynamics.
NASA Tech Briefs, August 1996. Volume 20, No. 8
NASA Technical Reports Server (NTRS)
1996-01-01
Topics covered include: Graphics and Simulation; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences; Life Sciences; Books and Reports
NASA Tech Briefs, September 2002. Volume 26, No. 9
NASA Technical Reports Server (NTRS)
2002-01-01
Topics include: a technology focus on data acquisition, electronic components and systems, software, materials, mechanics, machinery/automation, bio-medical, physical sciences, book and reports, and a special section of Photonics Tech Briefs.
Purchasing a Microprocessor System for Administrative Use in Schools.
ERIC Educational Resources Information Center
Marshall, David G.
1982-01-01
Describes a series of decision-making steps regarding the purchase of microcomputers for administrative use in schools. Includes such topics as defining information needs and purchasing computer hardware and software. (Author/JJD)
NASA Tech Briefs, March 2000. Volume 24, No. 3
NASA Technical Reports Server (NTRS)
2000-01-01
Topics include: Computer-Aided Design and Engineering; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery/Automation; Manufacturing/Fabrication; Mathematics and Information Sciences; Life Sciences; Books and Reports.
The integrated manual and automatic control of complex flight systems
NASA Technical Reports Server (NTRS)
Schmidt, David K.
1991-01-01
Research dealt with the general area of optimal flight control synthesis for manned flight vehicles. The work was generic; no specific vehicle was the focus of study. However, the class of vehicles generally considered were those for which high authority, multivariable control systems might be considered, for the purpose of stabilization and the achievement of optimal handling characteristics. Within this scope, the topics of study included several optimal control synthesis techniques, control-theoretic modeling of the human operator in flight control tasks, and the development of possible handling qualities metrics and/or measures of merit. Basic contributions were made in all these topics, including human operator (pilot) models for multi-loop tasks, optimal output feedback flight control synthesis techniques; experimental validations of the methods developed, and fundamental modeling studies of the air-to-air tracking and flared landing tasks.
Partially annotated bibliography for computer protection and related topics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Huskamp, J.C.
1976-07-20
References for the commonly cited technical papers in the area of computer protection are given. Great care is taken to exclude papers with no technical content or merit. For the purposes of this bibliography, computer protection is broadly defined to encompass all facets of the protection problem. The papers cover, but are not limited to, the topics of protection features in operating systems (e.g., MULTICS and HYDRA), hardware implementations of protection facilities (e.g., Honeywell 6180, System 250, BCC 5000, B6500), data base protection controls, confinement and protection models. Since computer protection is related to many other areas in computer sciencemore » and electrical engineering, a bibliography of related areas is included after the protection bibliography. These sections also include articles of general interest in the named areas which are not necessarily related to protection.« less
Text-Based On-Line Conferencing: A Conceptual and Empirical Analysis Using a Minimal Prototype.
ERIC Educational Resources Information Center
McCarthy, John C.; And Others
1993-01-01
Analyzes requirements for text-based online conferencing through the use of a minimal prototype. Topics discussed include prototyping with a minimal system; text-based communication; the system as a message passer versus the system as a shared data structure; and three exercises that showed how users worked with the prototype. (Contains 61…
System Dynamics in Medical Education: A Tool for Life
ERIC Educational Resources Information Center
Rubin, David M.; Richards, Christopher L.; Keene, Penelope A. C.; Paiker, Janice E.; Gray, A. Rosemary T.; Herron, Robyn F. R.; Russell, Megan J.; Wigdorowitz, Brian
2012-01-01
A course in system dynamics has been included in the first year of our university's six-year medical curriculum. System Dynamics is a discipline that facilitates the modelling, simulation and analysis of a wide range of problems in terms of two fundamental concepts viz. rates and levels. Many topics encountered in the medical school curriculum,…
Mission Medical Information System
NASA Technical Reports Server (NTRS)
Johnson-Throop, Kathy A.; Joe, John C.; Follansbee, Nicole M.
2008-01-01
This viewgraph presentation gives an overview of the Mission Medical Information System (MMIS). The topics include: 1) What is MMIS?; 2) MMIS Goals; 3) Terrestrial Health Information Technology Vision; 4) NASA Health Information Technology Needs; 5) Mission Medical Information System Components; 6) Electronic Medical Record; 7) Longitudinal Study of Astronaut Health (LSAH); 8) Methods; and 9) Data Submission Agreement (example).
The utilization of nonterrestrial materials. [resources for solar power satellite construction
NASA Technical Reports Server (NTRS)
1981-01-01
The development of research and technology programs on the user of nonterrestrial materials for space applications was considered with emphasis on the space power satellite system as a model of large space systems for which the use of nonterrestrial materials may be economically viable. Sample topics discussed include the mining of raw materials and the conversion of raw materials into useful products. These topics were considered against a background of the comparative costs of using terrestrial materials. Exploratory activities involved in the preparation of a nonterrestrial materials utilization program, and the human factors involved were also addressed. Several recommendations from the workshop are now incorporated in NASA activities.
Pariser, David
2009-01-01
The 2 primary classes of drugs used to treat atopic dermatitis (AD) are topical corticosteroids (TCSs) and topical calcineurin inhibitors (TCIs). For maximum efficacy, topical agents must efficiently penetrate the skin but, for optimal safety, should not be absorbed into the bloodstream. TCSs, a mainstay in AD treatment for more than 50 years, can potentially be absorbed into the systemic circulation, particularly when used on young children, for prolonged periods, or on areas of thin and sensitive skin, such as the eyelids, face, and flexures. There is a risk of cutaneous and systemic adverse events, including suppression of the hypothalamic-pituitary-adrenal axis and related sequelae, especially when potent or superpotent TCSs are used for extended periods. Ideally, TCSs should be used for short periods (2-4 weeks), but clinical reality often necessitates longer use. TCIs also effectively and safely treat AD, with the most commonly observed local adverse events being skin irritation and burning. These agents have demonstrated good penetration of the skin with minimal systemic absorption, as evidenced by low blood concentrations, and can be used safely on thin and sensitive skin. The use of mid-potency TCSs to treat acute flares involving skin of normal thickness, followed by the introduction of TCIs for maintenance therapy, constitutes an appropriate application of both drug classes. Pharmacists with a clear understanding of how both types of agents affect the systemic circulation have the opportunity to inform patients and caregivers about benefits and limitations of different therapeutic agents, address patient concerns about adverse events, and help patients understand how to use medical therapies appropriately.
From Answer Garden to Answer Jungle.
ERIC Educational Resources Information Center
Dron, Jon; Mitchell, Richard; Siviter, Phil
1998-01-01
The use of Usenet newsgroups in a computing and information systems classroom at the University of Brighton showed how Internet-based learning systems can encourage rapid evolution so that resources adapt to learners' needs. Although not always used as intended, and including off-topic distractions, newsgroups did accommodate learning styles and…
WebTOP: A 3D Interactive System for Teaching and Learning Optics
ERIC Educational Resources Information Center
Mzoughi, Taha; Herring, S. Davis; Foley, John T.; Morris, Matthew J.; Gilbert, Peter J.
2007-01-01
WebTOP is a three-dimensional, Web-based, interactive computer graphics system that helps instructors teach and students learn about waves and optics. Current subject areas include waves, geometrical optics, reflection and refraction, polarization, interference, diffraction, lasers, and scattering. Some of the topics covered are suited for…
Overview of the Phoenix Entry, Descent and Landing System
NASA Technical Reports Server (NTRS)
Grover, Rob
2005-01-01
A viewgraph presentation on the entry, descent and landing system of Phoenix is shown. The topics include: 1) Phoenix Mission Goals; 2) Payload; 3) Aeroshell/Entry Comparison; 4) Entry Trajectory Comparison; 5) Phoenix EDL Timeline; 6) Hypersonic Phase; 7) Parachute Phase; 8) Terminal Descent Phase; and 9) EDL Communications.
Intelligent Sensors and Components for On-Board ISHM
NASA Technical Reports Server (NTRS)
Figueroa, Jorge; Morris, Jon; Nickles, Donald; Schmalzel, Jorge; Rauth, David; Mahajan, Ajay; Utterbach, L.; Oesch, C.
2006-01-01
A viewgraph presentation on the development of intelligent sensors and components for on-board Integrated Systems Health Health Management (ISHM) is shown. The topics include: 1) Motivation; 2) Integrated Systems Health Management (ISHM); 3) Intelligent Components; 4) IEEE 1451; 5)Intelligent Sensors; 6) Application; and 7) Future Directions
Statistical Aspects of Reliability, Maintainability, and Availability.
1987-10-01
A total of 33 research reports were issued, and 35 papers were published in scientific journals or are in press. Research topics included optimal assembly of systems, multistate system theory , testing whether new is better than used nonparameter survival function estimation measuring information in censored models, generalizations of total positively and
An overview of the essential differences and similarities of system identification techniques
NASA Technical Reports Server (NTRS)
Mehra, Raman K.
1991-01-01
Information is given in the form of outlines, graphs, tables and charts. Topics include system identification, Bayesian statistical decision theory, Maximum Likelihood Estimation, identification methods, structural mode identification using a stochastic realization algorithm, and identification results regarding membrane simulations and X-29 flutter flight test data.
Memex Meets Madonna: Multimedia at the Intersection of Information and Entertainment.
ERIC Educational Resources Information Center
Kinney, Thomas
1992-01-01
Proposes a personal information management technology called Memex-TV that might develop from advances in entertainment technology. Topics addressed include capabilities of the new system, system design, the scenario for development of Memex-TV as an entertainment technology spin-off, current entertainment technology trends, a typical evening with…
Content and Context: Entropy Principle Experiments in a Course for Non-Science Students
ERIC Educational Resources Information Center
Bell, Jerry A.
1975-01-01
Describes an approach which begins with observations and systems familiar to the student and proceeds to develop and test models to explain them. Experimental topics include Brownian motion, a germinating cell, phase change of p-dichlorobenzene, extension and contraction of rubber, and an enzyme system. (GS)
NASA Technical Reports Server (NTRS)
Mandl, Dan; Sohlberg, Rob; Frye, Stu; Cappelaere, P.; Derezinski, L.; Ungar, Steve; Ames, Troy; Chien, Steve; Tran, Danny
2007-01-01
A viewgraph presentation on experiments with sensor webs and service oriented architectures is shown. The topics include: 1) Problem; 2) Basic Service Oriented Architecture Approach; 3) Series of Experiments; and 4) Next Experiments.
LSS systems planning and performance program
NASA Technical Reports Server (NTRS)
Mckenna, Victoria Jones; Dendy, Michael J.; Naumann, Charles B.; Rice, Sally A.; Weathers, John M.
1993-01-01
This report describes, using viewgraphs, the Marshall Space Flight Center's Large Space Structures Ground Test Facilities located in building 4619. Major topics include the Active Control Evaluation of Systems (ACES) Laboratory; the Control-Structures Interaction/Controls, Astrophysics, and Structures Experiment in Space (CSI/CASES); Advanced Development Facility; and the ACES Guest Investigator Program.
Foundations of Space Biology and Medicine. Volume 3: Space Medicine and Biotechnology
NASA Technical Reports Server (NTRS)
Calvin, M. (Editor); Gazenko, O. G. (Editor)
1975-01-01
The results of medical and biological research in space are presented. Specific topics discussed include: methods of providing life support systems for astronauts, characteristics of integrated life support systems, protection against adverse factors of space flight, selection and training of astronauts, and future space biomedical research.
Oxidation Ditches. Student Manual. Biological Treatment Process Control.
ERIC Educational Resources Information Center
Nelsen, David
The textual material for a two-lesson unit on oxidation ditches is presented in this student manual. Topics discussed in the first lesson (introduction, theory, and components) include: history of the oxidation ditch process; various designs of the oxidation ditch; multi-trench systems; carrousel system; advantages and disadvantages of the…
Workshop on Instructional Features and Instructor/Operator Station Design for Training Systems.
ERIC Educational Resources Information Center
Ricard, G. L., Ed.; And Others
These 19 papers review current research and development work related to the operation of the instructor's station of training systems, with emphasis on developing functional station specifications applicable to a variety of simulation-based training situations. Topics include (1) instructional features; (2) instructor/operator station research and…
Prototype Expert System for Climate Classification.
ERIC Educational Resources Information Center
Harris, Clay
Many students find climate classification laborious and time-consuming, and through their lack of repetition fail to grasp the details of classification. This paper describes an expert system for climate classification that is being developed at Middle Tennessee State University. Topics include: (1) an introduction to the nature of classification,…
Online Self-Organizing Social Systems: The Decentralized Future of Online Learning.
ERIC Educational Resources Information Center
Wiley, David A.; Edwards, Erin K.
2002-01-01
Describes an online self-organizing social system (OSOSS) which allows large numbers of individuals to self-organize in a highly decentralized manner to solve problems and accomplish other goals. Topics include scalability and bandwidth in online learning; self-organization; learning objects; instructional design underlying OSOSS, including…
Nanomaterials for Advanced Life Support in Advanced Life Support in Space systems
NASA Technical Reports Server (NTRS)
Allada, Rama Kumar; Moloney, Padraig; Yowell, Leonard
2006-01-01
A viewgraph presentation describing nanomaterial research at NASA Johnson Space Center with a focus on advanced life support in space systems is shown. The topics include: 1) Introduction; 2) Research and accomplishments in Carbon Dioxide Removal; 3) Research and Accomplishments in Water Purification; and 4) Next Steps
ERIC Educational Resources Information Center
Kibirige, Harry M.
1991-01-01
Discussion of the potential effects of fiber optic-based communication technology on information networks and systems design highlights library automation. Topics discussed include computers and telecommunications systems, the importance of information in national economies, microcomputers, local area networks (LANs), national computer networks,…
TOPSAT: Global space topographic mission
NASA Technical Reports Server (NTRS)
Vetrella, Sergio
1993-01-01
Viewgraphs on TOPSAT Global Space Topographic Mission are presented. Topics covered include: polar region applications; terrestrial ecosystem applications; stereo electro-optical sensors; space-based stereoscopic missions; optical stereo approach; radar interferometry; along track interferometry; TOPSAT-VISTA system approach; ISARA system approach; topographic mapping laser altimeter; and role of multi-beam laser altimeter.
A Project-Based Cooperative Approach to Teaching Sustainable Energy Systems
ERIC Educational Resources Information Center
Verbic, Gregor; Keerthisinghe, Chanaka; Chapman, Archie C.
2017-01-01
Engineering education is undergoing a restructuring driven by the needs of an increasingly multidisciplinary engineering profession. At the same time, power systems are transitioning toward future smart grids that will require power engineers with skills outside of the core power engineering domain. Since including new topics in the existing…
NASA STI Program Coordinating Council Twelfth Meeting: Standards
NASA Technical Reports Server (NTRS)
1994-01-01
The theme of this NASA Scientific and Technical Information Program Coordinating Council Meeting was standards and their formation and application. Topics covered included scientific and technical information architecture, the Open Systems Interconnection Transmission Control Protocol/Internet Protocol, Machine-Readable Cataloging (MARC) open system environment procurement, and the Government Information Locator Service.
International Instrumentation Symposium, 39th, Albuquerque, NM, May 2-6, 1993, Proceedings
NASA Astrophysics Data System (ADS)
Various papers on instrumentation are presented. The general topics addressed include: data acquisition and processing, wind tunnels, pressure measurements, thermal measurements, force measurements, aerospace, metrology, flow measurements, real-time systems, measurement uncertainty, data analysis and calibration, computer applications, special tests, reentry vehicle systems, and human engineering.
Deductive Error Diagnosis and Inductive Error Generalization for Intelligent Tutoring Systems.
ERIC Educational Resources Information Center
Hoppe, H. Ulrich
1994-01-01
Examines the deductive approach to error diagnosis for intelligent tutoring systems. Topics covered include the principles of the deductive approach to diagnosis; domain-specific heuristics to solve the problem of generalizing error patterns; and deductive diagnosis and the hypertext-based learning environment. (Contains 26 references.) (JLB)
Proceedings of Tenth Annual Software Engineering Workshop
NASA Technical Reports Server (NTRS)
1985-01-01
Papers are presented on the following topics: measurement of software technology, recent studies of the Software Engineering Lab, software management tools, expert systems, error seeding as a program validation technique, software quality assurance, software engineering environments (including knowledge-based environments), the Distributed Computing Design System, and various Ada experiments.
Aeronautical engineering. A continuing bibliography with indexes, supplement 127, October 1980
NASA Technical Reports Server (NTRS)
1980-01-01
A bibliography containing 431 abstracts addressing various topics in aeronautical engineering is given. The coverage includes engineering and theoretical aspects of design. construction, evaluation, testing, operation, and performance of aircraft (including aircraft engines) and associated components, equipment, and systems. It also includes research and development in aerodynamics, aeronautics, and ground support equipment for aeronautical vehicles.
1992-01-01
The results of these studies will be used to identify the most promising strategies for minimizing or eliminating the sources of damage. MUDAWAR ...NAVY Topic#: 92-097 DARPA Topic#: 92-145 NOVA MANAGFMENT, INC. MUDAWAR THERMAL SYSTEM, INC. ARMY Topic#: 92-087 NAVY Topic#: 92-136 ARMY Topic#: 92-089...TECHNOLOGIES, INC. MUDAWAR THERMAL SYSTEM. INC. NAVY Topic#: 92-120 NAVY Topic#: 92-137 FOSTER-MILLER, INC. MOUNTAIN OPTECH, INC. MSNW, INC. NAVY Topic#: 92-138
NASA Tech Briefs, October 1995. Volume 19, No. 10
NASA Technical Reports Server (NTRS)
1995-01-01
A special focus in this issue is Data acquisition and analysis. Topics covered include : Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Life Sciences; Mechanics; Machinery; Fabrication Technology; and Mathematics and Information Sciences. Also included in this issue are Laser Tech Briefs and Industry Focus: Motion Control/ Positioning Equipment
Crystal growth in fused solvent systems
NASA Technical Reports Server (NTRS)
Ulrich, D. R.; Noone, M. J.; Spear, K. E.; White, W. B.; Henry, E. C.
1973-01-01
Research is reported on the growth of electronic ceramic single crystals from solution for the future growth of crystals in a microgravity environment. Work included growth from fused or glass solvents and aqueous solutions. Topics discussed include: crystal identification and selection; aqueous solution growth of triglycine sulphate (TGS); and characterization of TGS.
Special Considerations for Networking Multimedia CD-ROM Titles.
ERIC Educational Resources Information Center
Wolfe, Janet L.
1994-01-01
Discusses issues to be considered when networking multimedia CD-ROMs. Topics addressed include CD-ROM networking software; license concerns; configurations for CD-ROM servers; data caching; SCSI devices; CD-ROM drives; workstation configurations, including minimum requirements for five popular CD-ROM titles; and system setup troubleshooting tips.…
Digging into Rocks with Young Children
ERIC Educational Resources Information Center
Trundle, Kathy; Miller, Heather; Krissek, Lawrence
2013-01-01
Rocks and other Earth materials are included in national, state, and local standards. For example, "A Framework for K-12 Science Education" (NRC 2012) contains topics related to Earth systems, which include the hydrosphere, atmosphere, biosphere, and geosphere. By second grade, students should be able to describe how most areas where…
The Mediated Classroom: A Systems Approach to Better University Instruction.
ERIC Educational Resources Information Center
Ranker, Richard A.
1995-01-01
Describes the design and equipment configuration of four mediated classrooms installed at a small university. Topics include audio, visual, and environmental subsystems; the teaching workstation; integration into learning, including teaching faculty how to use it and providing support services; and an instructional technology integration model.…
Agriculture Supplies & Services. Volume 3 of 3.
ERIC Educational Resources Information Center
Kansas State Univ., Manhattan.
The third of three volumes included in a secondary agricultural supplies and services curriculum guide, this volume contains twenty-five units of instruction in the area of agricultural mechanics. Among the unit topics included are (1) Farm Safety, (2) Ignition Systems; (3) Servicing Wheel Bearings, (4) Oxyacetylene Cutting, (5) Servicing the…
Advanced gas turbines breathe new life into vintage reheat units
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1994-04-01
This article describes the repowering of reheat units with advanced gas turbines. The topics of the article include a project overview, plant configuration including heat recovery steam generators and the plant-wide distributed control system, upgrade of existing steam turbines, gas turbine technology, reliability, availability, maintenance features, and training.
NASA Technical Reports Server (NTRS)
Phillips, Roger J.
1992-01-01
The Final Technical Report on tectonic evolution of Mars is presented. Two papers and an abstract are included. Topics addressed include: scientific rationale and requirements for a global seismic network on Mars, permanent uplift in magmatic systems with application to the Tharsis Region of Mars, and the geophysical signal of the Martian global dichotomy.