Effect of Fiber Orientation on Dynamic Compressive Properties of an Ultra-High Performance Concrete

DTIC Science & Technology

2017-08-01

measurements for LSFfiberOrient function for multiple cores. Elapsed time is the total time taken to run ; CPU time is the number of cores times the...Superscripts Maximum value during a test Measured value from a calibration run ...movement left or right. Before cutting, the Cor-Tuf Baseline beam was placed on the table and squared with the blade . The blade was then moved into

38 CFR 21.7576 - Entitlement charges.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Correspondence training; (3) Cooperative training; or (4) Apprenticeship or other on-job training. (Authority: 10... other on-job training, VA will make a charge against entitlement— (i) On the basis of total elapsed time... assistance allowance while undergoing apprenticeship or other on-job training, VA will make a charge against...

Disability perception in Menière's disease: when, how much and why?

PubMed

Soto-Varela, Andres; Huertas-Pardo, Belen; Gayoso-Diz, Pilar; Santos-Perez, Sofia; Sanchez-Sellero, Ines

2016-04-01

The purpose of the study was to evaluate self-perceived handicap in patients with definite Menière's disease (MD). A cross-sectional study was conducted. To examine the self-perception of disability, participants completed a DHI (Dizziness Handicap Inventory). Parameters compared with DHI scores: sex, age, unilateral/bilateral affectation, time elapsed since the onset of symptoms, pure-tone average (PTA), stages of MD, audiometric change (last 6 months), PTA in low frequencies (PTAl) and audiometric change in PTAl, subjective perception of fluctuating hearing threshold, tinnitus between attacks, number of vertiginous episodes (last 6 months), time elapsed since last attack, subjective perception of instability intercrises and Tumarkin attacks. 90 patients were included; they completed a total of 104 questionnaires. DHI scores ranged from 2 to 100 (average: 47.08, SD 24.45). In 29 cases (27.9 %) the disability perception was mild, in 43 (41.3 %) moderate, and in 32 (30.8 %) severe. Correlation between disability perception and some vestibular symptoms was found: number of typical attacks (last 6 months), time elapsed since last attack, instability intercrises and Tumarkin attacks. No relationship was found with the rest of variables. Disability perception in patients with MD depends primarily on vestibular symptoms (particularly, instability and frequency of attacks). So, we suggest to design a new staging system of MD taking into account both auditory criteria and also vestibular symptoms.

Elapsed Time Between the First Symptoms of Breast Cancer and Medical Help-Seeking Behavior and the Affecting Factors.

PubMed

Gözüm, Sebahat; Tuzcu, Ayla

Many studies have determined that the time between women's realization of first symptoms and seeking help from a healthcare professional is more than 1 month. The situation is defined as delay in medical help-seeking behavior (MHSB). The purpose of this study was to determine the time elapsed between the first symptoms of breast cancer and MHSB, as well as the factors contributing to the delay. In this descriptive study, the data were collected from 132 patients who received a diagnosis of breast cancer and are receiving treatment in the Oncology Clinic of Akdeniz University Hospital. The questionnaire used in the study was structured in 3 parts: sociodemographic characteristics, breast cancer history/screening behaviors, and psychological factors affecting MHSB. The elapsed time between patients' first symptoms and MHSB was classified into "normal" when it was less than 1 month, "delay" when it was between 1 and 3 months, "long-term delay" when it was more than 3 months, and "very serious delay" when it was more than 6 months. A total of 59.8% were classified as normal, 16.7% as delayed, 5.3% as a long-term delay, and 18.2% as a very serious delay after first symptoms. The delay in MHSB time was affected 18.55 times by "not caring/minding," 10.73 times by "fear," 7.13 times by "having more important problems," and 4.23 times by "realization of first symptoms" by themselves. Psychological factors were the most important determinants in delay. The MHSB time was less if those first realizing the symptoms were healthcare professionals. Healthcare professionals should direct women to screenings and train them to interpret symptoms correctly.

75 FR 41920 - Agency Information Collection; Activity Under OMB Review; Airline Service Quality Performance...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-19

... and analyze air traffic delays. Wheels-up and wheels-down times are used in conjunction with departure and arrival times to show the extent of ground delays. Actual elapsed flight time, wheels-down minus wheels- up time, is compared to scheduled elapsed flight time to identify airborne delays. The reporting...

A comparison of ambient casino sound and music: effects on dissociation and on perceptions of elapsed time while playing slot machines.

PubMed

Noseworthy, Theodore J; Finlay, Karen

2009-09-01

This research examined the effects of a casino's auditory character on estimates of elapsed time while gambling. More specifically, this study varied whether the sound heard while gambling was ambient casino sound alone or ambient casino sound accompanied by music. The tempo and volume of both the music and ambient sound were varied to manipulate temporal engagement and introspection. One hundred and sixty (males = 91) individuals played slot machines in groups of 5-8, after which they provided estimates of elapsed time. The findings showed that the typical ambient casino auditive environment, which characterizes the majority of gaming venues, promotes understated estimates of elapsed duration of play. In contrast, when music is introduced into the ambient casino environment, it appears to provide a cue of interval from which players can more accurately reconstruct elapsed duration of play. This is particularly the case when the tempo of the music is slow and the volume is high. Moreover, the confidence with which time estimates are held (as reflected by latency of response) is higher in an auditive environment with music than in an environment that is comprised of ambient casino sounds alone. Implications for casino management are discussed.

77 FR 33808 - Agency Information Collection; Activity Under OMB Review: Airline Service Quality Performance...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-07

... Administration uses Part 234 data to pinpoint and analyze air traffic delays. Wheels-up and wheels-down times are... elapsed flight time, wheels-down minus wheels- up time, is compared to scheduled elapsed flight time to... the air network, which enables the FAA to study the ripple effects of delays at hub airports. The data...

Impact and utilization studies of a PACS display station in an ICU setting

NASA Astrophysics Data System (ADS)

Andriole, Katherine P.; Storto, Maria L.; Gamsu, Gordon; Huang, H. K.

1996-05-01

An assessment of changes in health-care professional behavior as a result of the introduction of a PACS (picture archiving and communication system) display station to an adult medical- surgical intensive care unit (ICU) is investigated via pre- and post-PACs evaluations. ICU display station utilization and the impact on clinical operations are also examined. Parameters measured both pre- and post-PACS ICU display station placement include the number of films per patient day, the number of clinician reviews of a patient's images per day and the percentage of images on which the unit interacts with a radiologist. The elapsed times from the time of exposure to the time of: review by the referring physician, radiologist-unit interaction and clinical action based on image information are also measured. The results of this investigation suggest that the introduction of a PaCS display station in the ICU may reduce the number of exams per patient day, decrease the elapsed time from the time of exposure to the time of review by the unit clinician, and improve the time to clinical action. Note, however, that it does not appear to change the percentage of total images on which the unit interacts with a radiologist.

Investigation of Characteristics and Predictive Factors Affecting Mortality from Aluminum Phosphide Poisoning, Iran.

PubMed

Navabi, Seyed Mohammad Navabi; Navabi, Seyed Jafar; Aghaei, Abbas; Shaahmadi, Zahra; Heydari, Ruhollah

2018-05-27

Aluminum phosphide (ALP) or rice tablet is one of the most effective rodenticides used for the protection of grain storages from animals and rodents. ALP poisoning annually leads to mortality in human beings. The aim of this study was to evaluate the characteristics and predictive factors affecting mortality from ALP poisoning. This study evaluated patients with ALP poisoning referred to Imam Khomeini hospital in Kermanshah from 2014 to 2015. There are several data gathered from patient such as age, sex, number of consumed tablets, the number of attempts to commit suicide, elapsed time from consuming till treatment, blood pressure, PH, HCO3 and PCO2. Survivors (recovery) and non-survivors (death) from ALP poisoning are also evaluated in this study. Univariate logistic regression and multivariate analysis have been applied for data analysis. In this study, 48 patients were male and 29 patients were female, respectively (total 77 patient). The average age of survivors and non-survivors were 28.69 and 31.34 years, respectively. All cases (100%) of ALP poisoning were tried to commit suicide. The results showed that the main predictive variables of mortality from ALP poisoning were blood pressure, PH and elapsed time from consuming till treatment. The prognosis of death for patients with ALP poisoning can be determined by awareness of some of the main characteristics or factors such as blood pressure, PH and elapsed time from consuming till treatment. This can give a possibility for healthcare groups to consider more measures in patients with ALP poisoning.

29 CFR 2530.200b-3 - Determination of service to be credited to employees.

Code of Federal Regulations, 2011 CFR

2011-07-01

... the equivalencies permitted under this section, or the elapsed time method of crediting service permitted under this section, or the elapsed time method of crediting service permitted under § 2530.200b-9... applied. Thus, for example, a plan may provide that part-time employees are credited under the general...

Consistency of near-death experience accounts over two decades: are reports embellished over time?

PubMed

Greyson, Bruce

2007-06-01

"Near-death experiences," commonly reported after clinical death and resuscitation, may require intervention and, if reliable, may elucidate altered brain functioning under extreme stress. It has been speculated that accounts of near-death experiences are exaggerated over the years. The objective of this study was to test the reliability over two decades of accounts of near-death experiences. Seventy-two patients with near-death experience who had completed the NDE scale in the 1980s (63% of the original cohort still alive) completed the scale a second time, without reference to the original scale administration. The primary outcome was differences in NDE scale scores on the two administrations. The secondary outcome was the statistical association between differences in scores and years elapsed between the two administrations. Mean scores did not change significantly on the total NDE scale, its 4 factors, or its 16 items. Correlation coefficients between scores on the two administrations were significant at P<0.001 for the total NDE scale, for its 4 factors, and for its 16 items. Correlation coefficients between score changes and time elapsed between the two administrations were not significant for the total NDE scale, for its 4 factors, or for its 16 items. Contrary to expectation, accounts of near-death experiences, and particularly reports of their positive affect, were not embellished over a period of almost two decades. These data support the reliability of near-death experience accounts.

Sleep Loss Effects on Continuous Sustained Performance

DTIC Science & Technology

1981-04-24

i group as well as the 42-straight group. This may be either because the total amount of rest received by the 18-and-6 group before thc second day (6...ADDITION--NO ANSWER 42-STRRIGHT Lii SC 𔃻 ,:0 CbD .00 6 12.00 1𔄀.00 24.00 30.00 36.00 . ELAPSED TIME (HOURS) 0500 1100 1700 2300 0500 1100 1760 2300

Examination Phase of the Master's Thesis: A Plausible Cause of Delayed Completion of Graduate Studies at Makerere University, Uganda

ERIC Educational Resources Information Center

Oonyu, Joseph C.; Wamala, Robert

2012-01-01

This paper investigates the influence of the examination stage of student theses on the completion time of graduate studies at Makerere University, Uganda. The assessment is based on the administrative data of 504 Master's degree students in the 2000 to 2008 enrollment cohorts at the School of Education, Makerere University. The total elapsed time…

Transition from congress abstract to full paper: the case of a national Argentinean congress in clinical laboratory.

PubMed

Martínez, Ana M; Fink, Nilda E

2008-01-01

Transition from communications (abstracts) of an Argentinean congress and their publication as full papers was analyzed. No similar report was found for clinical laboratory in Latin America. A total of 388 communications from five congresses were identified, and searches were performed on the internet to find the publications. Pairs were established (1 communication, 1 publication), and characteristics were analyzed. In total, 10.8% of the communications were published. Mean time elapsed was 2+/-1.0 years (x +/- SD). A total of 62% of the publications appeared in Argentinean journals and 38% in foreign journals (5 in Spanish, 11 in English). Mean author number was 4.8+/-2.4 for communications and 5.1+/-2.3 for publications. In total, 59.5% of the publications changed the number and order of authors. Clinical Chemistry was the main topic (45.4% for communications, 38.1% for publications), followed by Microbiology (21.1%, 23.8%). Universities participated in 217 communications (55.9%) and 32 publications (76.2%), while other institutions participated in 171 communications (44.1%) and 10 publications (23.8%). Publication index was lower than for other congresses. Time elapsed was consistent with others. Preference for Argentinean journals may indicate a focus on local readers but also limitations in language skills. Variations in authorship arise from modifications of individual participation in the final work. More publications from all institutions are desirable. Differences of content were below those reported by others.

26 CFR 1.410(a)-7 - Elapsed time.

Code of Federal Regulations, 2011 CFR

2011-04-01

... period of severance from service in order to determine a “break in service” (see paragraph (a)(3)(v) of... employers maintaining the plan. The purpose of the period of severance is to apply the statutory “break in... plan using the elapsed time method of crediting service for one or more classifications of employees...

26 CFR 1.410(a)-7 - Elapsed time.

Code of Federal Regulations, 2012 CFR

2012-04-01

... period of severance from service in order to determine a “break in service” (see paragraph (a)(3)(v) of... employers maintaining the plan. The purpose of the period of severance is to apply the statutory “break in... plan using the elapsed time method of crediting service for one or more classifications of employees...

A Study on the Effectiveness of Lockup-Free Caches for a Reduced Instruction Set Computer (RISC) Processor

DTIC Science & Technology

1992-09-01

to acquire or develop effective simulation tools to observe the behavior of a RISC implementation as it executes different types of programs . We choose...Performance Computer performance is measured by the amount of the time required to execute a program . Performance encompasses two types of time, elapsed time...and CPU time. Elapsed time is the time required to execute a program from start to finish. It includes latency of input/output activities such as

Job Order Contracting: A Procurement Success Story

DTIC Science & Technology

1988-02-01

Engineering/Procurement processing time 279 CI4 TABLE C-2 JOC DELIVERY ORDER PROCESSING TIME Contract size and location Amount Elapsed time- ($000) days...Bragg 2.1 68 Monroe 2.1 196 Sill 2.2 3 bragg 2.3 32 C-5 Ii ~A¶A~.AL&A .LiA..hLI TABLE C-2 JOC DELIVERY ORDER PROCESSING TIME (Continued) Conrat szean...DEUVERY ORDER PROCESSING TIME (Continued) Amount Elapsed time- Contract size and location Amou daps($000) days Bragg S 14.7 11 Monroe 14.8 30 Monroe

The shelf-life of airborne laser scanning data for enhancing forest inventory inferences

Treesearch

Ronald E. McRoberts; Qi Chen; Dale D. Gormanson; Brian F. Walters

2018-01-01

The term shelf-life is used to characterize the elapsed time beyond which a commodity loses its usefulness. The term is most often used with reference to foods and medicines, but herein it is used to characterize the elapsed time beyond which airborne laser scanning (ALS) data are no longer useful for enhancing inferences for forest inventory...

Abstract Interface Specifications for the A-7E Device Interface Module.

DTIC Science & Technology

1980-11-20

Undesired events +GSINSAGE+ pl:time;O !+SINS attitude age +! %SINS not enabled% p2 :time:O !+SINS position age +! p3:time:O !+SINS velocity age +! +G SINS...attitude age +! The elapsed time since new valid attitude data was provided by the SINS hardware. !+SINS attitude valid+! True iff SINS attitude data is valid...horizontal plane. !+SINS position age +! The elapsed time since new valid position data was provided by the SINS hardware. !+SINS position valid+! True iff

Long-term changes of patient-reported quality of life after major trauma: The importance of the time elapsed after injury.

PubMed

Fleischhacker, Evi; Trentzsch, Heiko; Kuppinger, David; Meigel, Franziska; Beyer, Felix; Hartl, Wolfgang H

2018-02-01

Numerous studies have identified various risk factors for a poor health-related quality of life (HRQOL) after severe trauma. The relative importance of the time elapsed after injury, however, is unknown and results of clinical studies have been conflicting. A cross-sectional study was performed in two trauma centres using data from the German TraumaRegister DGU ® , which contained prospectively collected information on the type and severity of the injury, on critical care, and on outcome. To evaluate HRQOL in patients surviving more than 500days after the injury, we used a self-rating instrument, the EQ-5D which contains a visual analogue scale (EQ-VAS), and which allows the calculation of a global outcome indicator, the EQ-D5 index value. Complex statistical models were used to evaluate independent associations between the time elapsed after injury and a poor HRQOL. Of 380 contacted patients, follow-up assessments could be obtained in 168 patients (44.2%) 3.6±1.6 (SD) years after the injury. There was a linear association between the time elapsed after the injury and the% of contacted patients not participating in the study (p=0.013). In participating subjects, average EQ-5D index value was 0.599±0.299, and average EQ-VAS rating 67.8±22.0. A very poor quality of life (EQ-5D index value<0.6, EQ-VAS rating≤50) could be found in 43.5% and 28.0% of the patients, respectively. After adjusting for multiple confounders, the number of days elapsed after injury showed a complex non-linear and independent association with a poor HRQOL (low EQ-5D index value: p=0.027; low EQ-VAS rating: p=0.008). Frequencies of a poor HRQOL reached their minimum about four to five years after the injury and increased thereafter. There is an independent, U-shaped association between the frequency of extreme values of HRQOL and the time elapsed after injury. Time patterns of HRQOL may be sensitive to increasing rates of attrition since patients with a good outcome are less likely to respond to questionnaires. Time from injury should be incorporated into all future cross sectional studies trying to identify predictors of HRQOL. Copyright © 2017 Elsevier Ltd. All rights reserved.

Retrospective Time Perception in Korsakoff's Syndrome.

PubMed

El Haj, Mohamad; Nandrino, Jean-Louis; Kessels, Roy P C; Matton, Christian; Bacquet, Jean-Eudes; Urso, Laurent; Antoine, Pascal

2017-01-01

The authors investigated retrospective timing in participants with Korsakoff's syndrome. Patients were assessed on four retrospective tasks on which they were instructed to read three-digit numbers aloud (15 seconds), fill connected squares (30 seconds), decide whether words were abstract or concrete (45 seconds), or read aloud a text about mushroom picking (60 seconds). Participants were not aware of the task's timing until the end of the tasks, when they were asked to estimate the elapsed time. Results revealed an underestimation of the elapsed time in Korsakoff participants, suggesting that time is perceived to pass quickly for these participants.

Effect of virtual reality on time perception in patients receiving chemotherapy

PubMed Central

Kisby, Cassandra K.; Flint, Elizabeth P.

2013-01-01

Purpose Virtual reality (VR) during chemotherapy has resulted in an elapsed time compression effect, validating the attention diversion capabilities of VR. Using the framework of the pacemaker–accumulator cognitive model of time perception, this study explored the influence of age, gender, state anxiety, fatigue, and cancer diagnosis in predicting the difference between actual time elapsed during receipt of intravenous chemotherapy while immersed in a VR environment versus patient’s retrospective estimates of time elapsed during this treatment. Materials and methods This secondary analysis from three studies yielded a pooled sample of N=137 participants with breast, lung, or colon cancer. Each study employed a crossover design requiring two matched intravenous chemotherapy treatments, with participants randomly assigned to receive VR during one treatment. Regressions modeled the effect of demographic variables, diagnosis, and Piper Fatigue Scale and State Anxiety Inventory scores on the difference between actual and estimated time elapsed during chemotherapy with VR. Results In a forward regression model, three predictors (diagnosis, gender, and anxiety) explained a significant portion of the variability for altered time perception (F=5.06, p=0.0008). Diagnosis was the strongest predictor; individuals with breast and colon cancer perceived time passed more quickly. Conclusions VR is a noninvasive intervention that can make chemotherapy treatments more tolerable. Women with breast cancer are more likely and lung cancer patients less likely to experience altered time perception during VR (a possible indicator of effectiveness for this distraction intervention). Understanding factors that predict responses to interventions can help clinicians tailor coping strategies to meet each patient’s needs. PMID:20336327

Influence of surgical experience on the efficiency of discectomy in TLIF: a cadaveric testing in 40 levels.

PubMed

Pumberger, Matthias; Hughes, Alexander P; Girardi, Federico P; Gogia, Jaspaul; Kotwal, Suhel Y; Thaler, Christoph; Sama, Andrew A

2012-12-01

Cadaveric study. The purpose of this study was to assess the influence of surgical experience on the efficiency of lumbar discectomy in open transforaminal lumbar interbody fusion. There is limited knowledge about the efficiency of discectomy among surgeons. As a first study, we are evaluating the effect of surgical experience on it. Manual and powered discectomies were randomized and performed by 3 attending spine surgeons and 2 clinical spine fellows. Each discectomy procedure was analyzed for the area of complete endplate preparation, total elapsed time, and number of instrument passes. The surface area of discectomy at each endplate was measured utilizing digital imaging and the appropriate software. For the purpose of the analysis, the superior and the inferior endplates were divided into ipsilateral and contralateral halves, and each half was further divided into ventral and dorsal quadrants. Each quadrant was analyzed in a blinded manner by 2 observers. A total of 40 discectomies were performed on 9 fresh-frozen cadaveric torsos between the levels T12 and S1. A powered discectomy device was used in levels 9 and 11 by the attendings. Manual discectomy was performed in 11 levels by the spine fellows and 9 by the spine attendings. No significant difference was observed between the spine fellows and spine attendings when the manual instruments were used (P = 0.924). However, the spine attending surgeon group had a significantly increased total area of discectomy compared with the fellows (P = 0.003). No significant difference was observed between the groups when instrument passes or the total elapsed time were compared either utilizing the manual or the powered technique. Our results demonstrate that a satisfactory discectomy may be performed by surgeons with relatively less surgical experience in the transforaminal approach using a powered discectomy device.

A model for food and stimulus changes that signal time-based contingency changes.

PubMed

Cowie, Sarah; Davison, Michael; Elliffe, Douglas

2014-11-01

When the availability of reinforcers depends on time since an event, time functions as a discriminative stimulus. Behavioral control by elapsed time is generally weak, but may be enhanced by added stimuli that act as additional time markers. The present paper assessed the effect of brief and continuous added stimuli on control by time-based changes in the reinforcer differential, using a procedure in which the local reinforcer ratio reversed at a fixed time after the most recent reinforcer delivery. Local choice was enhanced by the presentation of the brief stimuli, even when the stimulus change signalled only elapsed time, but not the local reinforcer ratio. The effect of the brief stimulus presentations on choice decreased as a function of time since the most recent stimulus change. We compared the ability of several versions of a model of local choice to describe these data. The data were best described by a model which assumed that error in discriminating the local reinforcer ratio arose from imprecise discrimination of reinforcers in both time and space, suggesting that timing behavior is controlled not only by discrimination elapsed time, but by discrimination of the reinforcer differential in time. © Society for the Experimental Analysis of Behavior.

Earth's Bow Shock: Elapsed-Time Observations by Two Closely Spaced Satellites.

PubMed

Greenstadt, E W; Green, I M; Colburn, D S

1968-11-22

Coordinated observations of the earth's bow shock were made as Vela 3A and Explorer 33 passed within 6 earth radii of each other. Elapsed time measurements of shock motion give directly determined velocities in the range 1 to 10 kilometers per second and establish the existence of two regions, one of large amplitude magnetic "shock" oscillations and another of smaller, sunward, upstream oscillations. Each region is as thick as 1 earth radius, or more.

Astronaut Ronald Evans photographed during transearth coast EVA

NASA Image and Video Library

1972-12-17

AS17-152-23391 (17 Dec. 1972) --- Astronaut Ronald E. Evans is photographed performing extravehicular activity during the Apollo 17 spacecraft's trans-Earth coast. During his EVA, Evans, command module pilot, retrieved film cassettes from the lunar sounder, mapping camera and panoramic camera. The cylindrical object at Evans' left side is the mapping camera cassette. The total time for the trans-Earth EVA was one hour, seven minutes, 18 seconds, starting at ground elapsed time of 257:25 (2:28 p.m.) and ending at G.E.T. of 258:42 (3:35 p.m.) on Sunday, Dec. 17, 1972.

Determining a bisection bandwidth for a multi-node data communications network

DOEpatents

Faraj, Ahmad A.

2010-01-26

Methods, systems, and products are disclosed for determining a bisection bandwidth for a multi-node data communications network that include: partitioning nodes in the network into a first sub-network and a second sub-network in dependence upon a topology of the network; sending, by each node in the first sub-network to a destination node in the second sub-network, a first message having a predetermined message size; receiving, by each node in the first sub-network from a source node in the second sub-network, a second message; measuring, by each node in the first sub-network, the elapsed communications time between the sending of the first message and the receiving of the second message; selecting the longest elapsed communications time; and calculating the bisection bandwidth for the network in dependence upon the number of the nodes in the first sub-network, the predetermined message size of the first test message, and the longest elapsed communications time.

Surface microhardness of a resin composite exposed to a "first-generation" LED curing lamp, in vitro.

PubMed

Keogh, Pauraic; Ray, Noel J; Lynch, Christopher D; Burke, Francis M; Hannigan, Ailish

2004-12-01

This investigation determined the minimum exposure times consistent with optimised surface microhardness parameters for a commercial resin composite cured using a "first-generation" light-emitting diode activation lamp. Disk specimens were exposed and surface microhardness numbers measured at the top and bottom surfaces for elapsed times of 1 hour and 24 hours. Bottom/top microhardness number ratios were also calculated. Most microhardness data increased significantly over the elapsed time interval but microhardness ratios (bottom/top) were dependent on exposure time only. A minimum exposure of 40 secs is appropriate to optimise microhardness parameters for the combination of resin composite and lamp investigated.

Effect of Spreading Time on Contact Angle of Nanofluid on the Surface of Stainless Steel AISI 316 and Zircalloy 4

NASA Astrophysics Data System (ADS)

Prajitno, D. H.; Trisnawan, V.; Syarif, D. G.

2017-05-01

The solid surface tension plays an important role in the heat and mass transfer system for heat exchanger equipment. In the nuclear power plant industry, the stainless steel AISI 316 and Zircalloy 4 have been used for long time as structure materials. The purpose of the experimental is to study solid state surface tension behavior by measure contact angle Nano fluid contain nano particle alumina on metal surface of stainless steel AISI 316 and Zircalloy 4 by sessile drop method. The experiment is to measure the static contact angle and drop nano fluid contains nano particle alumina on stainless steel 316 and zircalloy 4 with different spreading time from 1 to 30 minute. It was observed that stainless steel 316 and zircalloy 4 lose their hydrophobic properties with increasing elapsed time during drop of nano fluid on the surface of alloy. As a result the contact angle of nano fluid on surface of metal is decrease with increasing elapsed time. While the magnitude diameter of drop nano fluid and wetting surface is increase with increasing elapsed time on the surface of the stainless steel SS 316 and Zircalloy 4.

Structure and phylogenetic diversity of post-fire ectomycorrhizal communities of maritime pine.

PubMed

Rincón, A; Santamaría, B P; Ocaña, L; Verdú, M

2014-02-01

Environmental disturbances define the diversity and assemblage of species, affecting the functioning of ecosystems. Fire is a major disturbance of Mediterranean pine forests. Pines are highly dependent on the ectomycorrhizal (EM) fungal symbiosis, which is critical for tree recruitment under primary succession. To determine the effects of time since fire on the structure and recovery of EM fungal communities, we surveyed the young Pinus pinaster regenerate in three sites differing in the elapsed time after the last fire event. Pine roots were collected, and EM fungi characterized by sequencing the internal transcribed spacer (ITS) and the large subunit (LSU) regions of the nuclear ribosomal (nr)-DNA. The effects of the elapsed time after fire on the EM community structure (richness, presence/absence of fungi, phylogenetic diversity) and on soil properties were analysed.Fungal richness decreased with the elapsed time since the fire; although, the phylogenetic diversity of the EM community increased. Soil properties were different depending on the elapsed time after fire and particularly, the organic matter, carbon-to-nitrogen (C/N) ratio, nitrogen and iron significantly correlated with the assemblage of fungal species. Ascomycetes, particularly Tuberaceae and Pezizales, were significantly over-represented on saplings in the burned site. On seedlings, a significant over-representation of Rhizopogonaceae and Atheliaceae was observed in the most recently burned site, while other fungi (i.e. Cortinariaceae) were significantly under-represented. Our results are consistent with the hypothesis that fire can act as a selective agent by printing a phylogenetic signal on the EM fungal communities associated with naturally regenerated pines, pointing out to some groups as potential fire-adapted fungi.

An evaluation of superminicomputers for thermal analysis

NASA Technical Reports Server (NTRS)

Storaasli, O. O.; Vidal, J. B.; Jones, G. K.

1962-01-01

The feasibility and cost effectiveness of solving thermal analysis problems on superminicomputers is demonstrated. Conventional thermal analysis and the changing computer environment, computer hardware and software used, six thermal analysis test problems, performance of superminicomputers (CPU time, accuracy, turnaround, and cost) and comparison with large computers are considered. Although the CPU times for superminicomputers were 15 to 30 times greater than the fastest mainframe computer, the minimum cost to obtain the solutions on superminicomputers was from 11 percent to 59 percent of the cost of mainframe solutions. The turnaround (elapsed) time is highly dependent on the computer load, but for large problems, superminicomputers produced results in less elapsed time than a typically loaded mainframe computer.

MO-F-CAMPUS-T-05: SQL Database Queries to Determine Treatment Planning Resource Usage

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fox, C; Gladstone, D

2015-06-15

Purpose: A radiation oncology clinic’s treatment capacity is traditionally thought to be limited by the number of machines in the clinic. As the number of fractions per course decrease and the number of adaptive plans increase, the question of how many treatment plans a clinic can plan becomes increasingly important. This work seeks to lay the ground work for assessing treatment planning resource usage. Methods: Care path templates were created using the Aria 11 care path interface. Care path tasks included key steps in the treatment planning process from the completion of CT simulation through the first radiation treatment. SQLmore » Server Management Studio was used to run SQL queries to extract task completion time stamps along with care path template information and diagnosis codes from the Aria database. 6 months of planning cycles were evaluated. Elapsed time was evaluated in terms of work hours within Monday – Friday, 7am to 5pm. Results: For the 195 validated treatment planning cycles, the average time for planning and MD review was 22.8 hours. Of those cases 33 were categorized as urgent. The average planning time for urgent plans was 5 hours. A strong correlation between diagnosis code and range of elapsed planning time was as well as between elapsed time and select diagnosis codes was observed. It was also observed that tasks were more likely to be completed on the date due than the time that they were due. Follow-up confirmed that most users did not look at the due time. Conclusion: Evaluation of elapsed planning time and other tasks suggest that care paths should be adjusted to allow for different contouring and planning times for certain diagnosis codes and urgent cases. Additional clinic training around task due times vs dates or a structuring of care paths around due dates is also needed.« less

Flutter optimization in fighter aircraft design

NASA Technical Reports Server (NTRS)

Triplett, W. E.

1984-01-01

The efficient design of aircraft structure involves a series of compromises among various engineering disciplines. These compromises are necessary to ensure the best overall design. To effectively reconcile the various technical constraints requires a number of design iterations, with the accompanying long elapsed time. Automated procedures can reduce the elapsed time, improve productivity and hold the promise of optimum designs which may be missed by batch processing. Several examples are given of optimization applications including aeroelastic constraints. Particular attention is given to the success or failure of each example and the lessons learned. The specific applications are shown. The final two applications were made recently.

Monitoring electrolyte concentrations in redox flow battery systems

DOEpatents

Chang, On Kok; Sopchak, David Andrew; Pham, Ai Quoc; Kinoshita, Kimio

2015-03-17

Methods, systems and structures for monitoring, managing electrolyte concentrations in redox flow batteries are provided by introducing a first quantity of a liquid electrolyte into a first chamber of a test cell and introducing a second quantity of the liquid electrolyte into a second chamber of the test cell. The method further provides for measuring a voltage of the test cell, measuring an elapsed time from the test cell reaching a first voltage until the test cell reaches a second voltage; and determining a degree of imbalance of the liquid electrolyte based on the elapsed time.

The most recent large earthquake on the Rodgers Creek fault, San Francisco bay area

USGS Publications Warehouse

Hecker, S.; Pantosti, D.; Schwartz, D.P.; Hamilton, J.C.; Reidy, L.M.; Powers, T.J.

2005-01-01

The Rodgers Creek fault (RCF) is a principal component of the San Andreas fault system north of San Francisco. No evidence appears in the historical record of a large earthquake on the RCF, implying that the most recent earthquake (MRE) occurred before 1824, when a Franciscan mission was built near the fault at Sonoma, and probably before 1776, when a mission and presidio were built in San Francisco. The first appearance of nonnative pollen in the stratigraphic record at the Triangle G Ranch study site on the south-central reach of the RCF confirms that the MRE occurred before local settlement and the beginning of livestock grazing. Chronological modeling of earthquake age using radiocarbon-dated charcoal from near the top of a faulted alluvial sequence at the site indicates that the MRE occurred no earlier than A.D. 1690 and most likely occurred after A.D. 1715. With these age constraints, we know that the elapsed time since the MRE on the RCF is more than 181 years and less than 315 years and is probably between 229 and 290 years. This elapsed time is similar to published recurrence-interval estimates of 131 to 370 years (preferred value of 230 years) and 136 to 345 years (mean of 205 years), calculated from geologic data and a regional earthquake model, respectively. Importantly, then, the elapsed time may have reached or exceeded the average recurrence time for the fault. The age of the MRE on the RCF is similar to the age of prehistoric surface rupture on the northern and southern sections of the Hayward fault to the south. This suggests possible rupture scenarios that involve simultaneous rupture of the Rodgers Creek and Hayward faults. A buried channel is offset 2.2 (+ 1.2, - 0.8) m along one side of a pressure ridge at the Triangle G Ranch site. This provides a minimum estimate of right-lateral slip during the MRE at this location. Total slip at the site may be similar to, but is probably greater than, the 2 (+ 0.3, - 0.2) m measured previously at the nearby Beebe Ranch site.

VizieR Online Data Catalog: Flaring gamma-ray sources; LAT 7.4yr (2FAV) (Abdollahi+, 2017)

NASA Astrophysics Data System (ADS)

Abdollahi, S.; Ackermann, M.; Ajello, M.; Albert, A.; Baldini, L.; Ballet, J.; Barbiellini, G.; Bastieri, D.; Becerra Gonzalez, J.; Bellazzini, R.; Bissaldi, E.; Blandford, R. D.; Bloom, E. D.; Bonino, R.; Bottacini, E.; Bregeon, J.; Bruel, P.; Buehler, R.; Buson, S.; Cameron, R. A.; Caragiulo, M.; Caraveo, P. A.; Cavazzuti, E.; Cecchi, C.; Chekhtman, A.; Cheung, C. C.; Chiaro, G.; Ciprini, S.; Conrad, J.; Costantin, D.; Costanza, F.; Cutini, S.; D'Ammando, F.; de Palma, F.; Desai, A.; Desiante, R.; Digel, S. W.; di Lalla, N.; di Mauro, M.; di Venere, L.; Donaggio, B.; Drell, P. S.; Favuzzi, C.; Fegan, S. J.; Ferrara, E. C.; Focke, W. B.; Franckowiak, A.; Fukazawa, Y.; Funk, S.; Fusco, P.; Gargano, F.; Gasparrini, D.; Giglietto, N.; Giomi, M.; Giordano, F.; Giroletti, M.; Glanzman, T.; Green, D.; Grenier, I. A.; Grove, J. E.; Guillemot, L.; Guiriec, S.; Hays, E.; Horan, D.; Jogler, T.; Johannesson, G.; Johnson, A. S.; Kocevski, D.; Kuss, M.; La Mura, G.; Larsson, S.; Latronico, L.; Li, J.; Longo, F.; Loparco, F.; Lovellette, M. N.; Lubrano, P.; Magill, J. D.; Mal! Dera, S.; Manfreda, A.; Mayer, M.; Mazziotta, M. N.; Michelson, P. F.; Mitthumsiri, W.; Mizuno, T.; Monzani, M. E.; Morselli, A.; Moskalenko, I. V.; Negro, M.; Nuss, E.; Ohsugi, T.; Omodei, N.; Orienti, M.; Orlando, E.; Paliya, V. S.; Paneque, D.; Perkins, J. S.; Persic, M.; Pesce-Rollins, M.; Petrosian, V.; Piron, F.; Porter, T. A.; Principe, G.; Raino, S.; Rando, R.; Razzano, M.; Razzaque, S.; Reimer, A.; Reimer, O.; Sgro, C.; Simone, D.; Siskind, E. J.; Spada, F.; Spandre, G.; Spinelli, P.; Stawarz, L.; Suson, D. J.; Takahashi, M.; Tanaka, K.; Thayer, J. B.; Thompson, D. J.; Torres, D. F.; Torresi, E.; Tosti, G.; Troja, E.; Vianello, G.; Wood, K. S.

2018-04-01

To build the second catalog of flaring gamma-ray sources (2FAV) catalog, we apply the Fermi All-sky Variability Analysis (FAVA; Ackermann+ 2013, J/ApJ/771/57) to the first 387 weeks of Fermi observations, from Mission Elapsed Time (MET) 239557418 to 473615018, or Modified Julian Date (MJD) from 54682 (2008 August 4) to 57391 (2016 January 4). In this time range, a total of 7106 seed flares were found, roughly 18 per week. As for the previous catalog, FAVA uses weekly time bins. Two independent energy bands are used, 0.1-0.8GeV and 0.8-300GeV, to enhance the sensitivity to spectrally soft and hard flares, respectively. (2 data files).

Cell-free fetal DNA (SRY locus) concentration in maternal plasma is directly correlated to the time elapsed from the onset of preeclampsia to the collection of blood.

PubMed

Farina, Antonio; Sekizawa, Akihiko; Rizzo, Nicola; Concu, Manuela; Banzola, Irina; Carinci, Paolo; Simonazzi, Giuliana; Okai, Takashi

2004-04-01

To determine (1) if fetal DNA (fDNA) in the maternal circulation in women affected by preeclampsia correlates with the time elapsed from the onset of symptoms to the time of blood collection, and (2) if the inclusion of this variable improves the discrimination between affected and unaffected patients by using fDNA distributions. Plasma were collected from 34 women at 33.7 +/- 3.9 weeks' gestation, affected by preeclampsia, and bearing a single male fetus. fDNA was extracted from 1.5-mL plasma samples, and the SRY and beta-globin gene were analyzed by real-time quantitative PCR. MoMs (multiple of the control median) were calculated by using a log equation of 102 normal cases. Log MoMs were then plotted against the time elapsed from onset of symptoms to blood collection (expressed in days) by means of a log-linear regression. Adjusted MoMs were then calculated. ROC curves were used to test the discrimination obtained by using adjusted MoMs. The median MoMs of controls and preeclamptic patients were 1.00 +/- 1.53 and 2.62 +/- 2.70 respectively. By plotting log MoM fDNA against the time elapsed from onset of symptoms to blood collection, we found a significant positive correlation, (p-value < 0.001, R2 = 0.55, F = 38.97, from 1 to 50 days). The adjusted median fDNA MoM was 2.66 +/- 2.50. Areas under the curves, as estimated by ROC curves, were 76.7 for unadjusted and 85.5 for adjusted MoMs respectively (p-value = 0.02). The effect of a further covariate showed that (1) fDNA passage from trophoblasts to maternal circulation for unit of time is proportional to the duration of the damage and that (2) increased discrimination can be obtained in comparison to normal subjects. Copyright 2004 John Wiley & Sons, Ltd.

Cognitive rehabilitation therapy after acquired brain injury in Argentina: psychosocial outcomes in connection with the time elapsed before treatment initiation.

PubMed

Saux, Gastón; Demey, Ignacio; Rojas, Galeno; Feldberg, Carolina

2014-01-01

To examine the effect of cognitive rehabilitation therapy (CRT) on psychosocial outcomes in Argentinean patients with acquired brain injury (ABI), in connection with the time elapsed between injury and treatment initiation. Self-reported data from patients in a naturalistic setting was collected before and after CRT. An outpatient sample of 75 Spanish-speaking patients with cognitive disturbances secondary to ABI (49 male/26 female, age: 50.2 ± 20.1 years; education 14.3 ± 3.2 years) completed a set of scales on their daily living activities, memory self-perception, quality-of-life and mood. Single and multi-group analyses were conducted, considering pre- and post- responses and the time elapsed between injury and treatment initiation. The influence of socio-demographic moderators was controlled during comparisons. Results suggest an improvement in several psychosocial indicators after treatment. Additionally, correlations and group comparisons showed greater improvement in subjective memory and quality-of-life self-reports in patients who began treatment earlier than those who began treatment after a longer time period. Overall, results suggest that CRT is associated with positive results in different areas of the psychosocial domain and that post-injury time can mediate this effect.

Brown bear sperm double freezing: Effect of elapsed time and use of PureSperm(®) gradient between freeze-thaw cycles.

PubMed

Alvarez-Rodríguez, Manuel; Alvarez, Mercedes; López-Urueña, Elena; Martínez-Rodriguez, Carmen; Borragan, Santiago; Anel-López, Luis; de Paz, Paulino; Anel, Luis

2013-12-01

The use of sexed spermatozoa has great potential to captive population management in endangered wildlife. The problem is that the sex-sorting facility is a long distance from the semen collection place and to overcome this difficulty two freeze-thaw cycles may be necessary. In this study, effects of refreezing on brown bear electroejaculated spermatozoa were analyzed. We carried out two experiments: (1) to assess the effects of the two freezing-thawing cycles on sperm quality and to analyze three different elapsed times between freezing-thawing cycles (30, 90 and 180 min), and (2) to analyze the use of PureSperm between freezing-thawing cycles to select a more motile and viable sperm subpopulation which better survived first freezing. The motility, viability and undamaged acrosomes were significantly reduced after the second thawing respect to first thawing into each elapsed time group, but the elapsed times did not significantly affect the viability and acrosome status although motility was damaged. Our results with the PureSperm gradient showed higher values of viability in freezability of select sample (pellet) respect to the rest of the groups and it also showed a significant decrease in the number of acrosome damaged. In summary, the double freezing of bear semen selected by gradient centrifugation is qualitatively efficient, and thus could be useful to carry out a sex-sorting of frozen-thawed bear spermatozoa before to send the cryopreserved sample to a biobank. Given the low recovery of spermatozoa after applying a selection gradient, further studies will be needed to increase the recovery rate without damaging of the cell quality. Copyright © 2013 Elsevier Inc. All rights reserved.

Elapsed decision time affects the weighting of prior probability in a perceptual decision task

PubMed Central

Hanks, Timothy D.; Mazurek, Mark E.; Kiani, Roozbeh; Hopp, Elizabeth; Shadlen, Michael N.

2012-01-01

Decisions are often based on a combination of new evidence with prior knowledge of the probable best choice. Optimal combination requires knowledge about the reliability of evidence, but in many realistic situations, this is unknown. Here we propose and test a novel theory: the brain exploits elapsed time during decision formation to combine sensory evidence with prior probability. Elapsed time is useful because (i) decisions that linger tend to arise from less reliable evidence, and (ii) the expected accuracy at a given decision time depends on the reliability of the evidence gathered up to that point. These regularities allow the brain to combine prior information with sensory evidence by weighting the latter in accordance with reliability. To test this theory, we manipulated the prior probability of the rewarded choice while subjects performed a reaction-time discrimination of motion direction using a range of stimulus reliabilities that varied from trial to trial. The theory explains the effect of prior probability on choice and reaction time over a wide range of stimulus strengths. We found that prior probability was incorporated into the decision process as a dynamic bias signal that increases as a function of decision time. This bias signal depends on the speed-accuracy setting of human subjects, and it is reflected in the firing rates of neurons in the lateral intraparietal cortex (LIP) of rhesus monkeys performing this task. PMID:21525274

Elapsed decision time affects the weighting of prior probability in a perceptual decision task.

PubMed

Hanks, Timothy D; Mazurek, Mark E; Kiani, Roozbeh; Hopp, Elisabeth; Shadlen, Michael N

2011-04-27

Decisions are often based on a combination of new evidence with prior knowledge of the probable best choice. Optimal combination requires knowledge about the reliability of evidence, but in many realistic situations, this is unknown. Here we propose and test a novel theory: the brain exploits elapsed time during decision formation to combine sensory evidence with prior probability. Elapsed time is useful because (1) decisions that linger tend to arise from less reliable evidence, and (2) the expected accuracy at a given decision time depends on the reliability of the evidence gathered up to that point. These regularities allow the brain to combine prior information with sensory evidence by weighting the latter in accordance with reliability. To test this theory, we manipulated the prior probability of the rewarded choice while subjects performed a reaction-time discrimination of motion direction using a range of stimulus reliabilities that varied from trial to trial. The theory explains the effect of prior probability on choice and reaction time over a wide range of stimulus strengths. We found that prior probability was incorporated into the decision process as a dynamic bias signal that increases as a function of decision time. This bias signal depends on the speed-accuracy setting of human subjects, and it is reflected in the firing rates of neurons in the lateral intraparietal area (LIP) of rhesus monkeys performing this task.

Evaluating the bakeout effectiveness of RTV-S691 silicone adhesive by measuring outgassing rate

NASA Astrophysics Data System (ADS)

Miyazaki, Eiji; Miura, Yuka; Numata, Osamu; Yamanaka, Riyo; Baba, Susumu; Ishizawa, Junichiro; Kimoto, Yugo; Tamura, Takashi

2014-09-01

Outgassing rate measurements are basically performed for fresh materials, e.g. just cured adhesives, paints, etc. and reveal a lot about how the material can behave as a contamination source. It is also important to determine the bakeout process sufficiently. In the present study, a typical silicone adhesive for use in space, RTV S-691, Wacker Chemie, was selected for the measurement. Two cured specimens, 40 × 40 mm in size, were applied for several isothermal tests under identical conditions: a specimen at 125 degrees C for 144 hours with CQCM at -193 degrees C to measure TML. Consequently, it was determined that the TML and TML rate could be reduced by bakeout as expected. It also emerged that a longer bakeout, i.e. a longer cumulative bakeout time, for the material would reduce the TML and TML rate more effectively. The results suggest that bakeout mainly affects the behavior in the "low-rate" phase, whereby the TML rate curve can be divided into two phases. The elapsed time for a specimen can also be considered the cumulative test time. Based on the cumulative elapsed time, the TML rate curve is replotted and a correlation emerges between the cumulative bakeout time and TML rate. The first measurement data of TML and the TML rate could be affected by the stored time from cure, which might result from the change in unreacted substances declining as the stored time elapsed.

Application of artificial neural networks to composite ply micromechanics

NASA Technical Reports Server (NTRS)

Brown, D. A.; Murthy, P. L. N.; Berke, L.

1991-01-01

Artificial neural networks can provide improved computational efficiency relative to existing methods when an algorithmic description of functional relationships is either totally unavailable or is complex in nature. For complex calculations, significant reductions in elapsed computation time are possible. The primary goal is to demonstrate the applicability of artificial neural networks to composite material characterization. As a test case, a neural network was trained to accurately predict composite hygral, thermal, and mechanical properties when provided with basic information concerning the environment, constituent materials, and component ratios used in the creation of the composite. A brief introduction on neural networks is provided along with a description of the project itself.

Central nervous system drug consumption depending on the time between symptom onset and the diagnosis of Alzheimer's disease: an analysis by the Registry of Dementias of Girona.

PubMed

Calvó-Perxas, Laia; López-Pousa, Secundino; Vilalta-Franch, Joan; Turró-Garriga, Oriol; Blankenburg, Michael; Febrer, Laia; Flaqué, Margarida; Vallmajó, Natàlia; Aguirregomozcorta, Maria; Genís, David; Casas, Isabel; Perkal, Héctor; Coromina, Joan; Garre-Olmo, Josep

2012-01-01

To describe central nervous system (CNS) drug consumption patterns depending on the time to diagnosis of Alzheimer's disease (AD), and to check whether the cases diagnosed later are associated with greater severity and consuming more CNS drugs. Cross-sectional study using 952 cases of the Registry of Dementias of Girona. A binary logistic regression was used to detect variables associated with the use of CNS drugs depending on the time to diagnosis. CNS drugs were consumed by 95.8% of the AD patients. Only antipsychotics presented a statistically significant increase in the frequency of prescription to patients with longer time elapsed from symptom onset to AD diagnosis. Longer time elapsed from the onset of symptoms to the diagnosis resulted in increased probability of antipsychotic consumption. Copyright © 2012 S. Karger AG, Basel.

49 CFR 236.831 - Time, delay.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Time, delay. 236.831 Section 236.831 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Time, delay. As applied to an automatic train stop or train control system, the time which elapses...

Two mantle domains and the time scales of fluid transfer beneath the Vanuatu arc

NASA Astrophysics Data System (ADS)

Turner, Simon P.; Peate, David W.; Hawkesworth, Chris J.; Eggins, Stephen M.; Crawford, Anthony J.

1999-11-01

U-Th isotope disequilibria can provide constraints on the time elapsed since fluid addition to the mantle wedge beneath island arcs. The Vanuatu arc offers new insights into these processes because Pb isotopes there are not dominated by components from the subducting plate and so preserve the signatures of the mantle wedge. The Pb isotope data document the presence of separate Pacific and Indian mantle domains beneath the arc volcanoes. The Indian mantle was brought beneath the central part of the arc from the backarc by collision with the D'Entrecasteaux Ridge, resulting in a slowing of subduction there. The distinction in the mantle wedge composition is also uniquely apparent in U-Th isotope data, which define two subparallel arrays on the U-Th equiline diagram, one anchored to high U/Th Pacific mantle and the other to lower U/Th Indian mantle. These data provide clear evidence of the effects of variable mantle composition on U-Th isotope disequilibria. We argue that such arrays faithfully record the time elapsed since fluid release from the subducting plate. The data indicate that this occurred ca. 16 ka in the area of collision and slow subduction, but ca. 60 ka where the rate of subduction is substantially faster. This suggests a link between the rate of subduction and the time elapsed since fluid release.

EPQ model with learning consideration, imperfect production and partial backlogging in fuzzy random environment

NASA Astrophysics Data System (ADS)

Shankar Kumar, Ravi; Goswami, A.

2015-06-01

The article scrutinises the learning effect of the unit production time on optimal lot size for the uncertain and imprecise imperfect production process, wherein shortages are permissible and partially backlogged. Contextually, we contemplate the fuzzy chance of production process shifting from an 'in-control' state to an 'out-of-control' state and re-work facility of imperfect quality of produced items. The elapsed time until the process shifts is considered as a fuzzy random variable, and consequently, fuzzy random total cost per unit time is derived. Fuzzy expectation and signed distance method are used to transform the fuzzy random cost function into an equivalent crisp function. The results are illustrated with the help of numerical example. Finally, sensitivity analysis of the optimal solution with respect to major parameters is carried out.

The effect of time-dependent macromolecular crowding on the kinetics of protein aggregation: a simple model for the onset of age-related neurodegenerative disease

NASA Astrophysics Data System (ADS)

Minton, Allen

2014-08-01

A linear increase in the concentration of "inert" macromolecules with time is incorporated into simple excluded volume models for protein condensation or fibrillation. Such models predict a long latent period during which no significant amount of protein aggregates, followed by a steep increase in the total amount of aggregate. The elapsed time at which these models predict half-conversion of model protein to aggregate varies by less than a factor of two when the intrinsic rate constant for condensation or fibril growth of the protein is varied over many orders of magnitude. It is suggested that this concept can explain why the symptoms of neurodegenerative diseases associated with the aggregation of very different proteins and peptides appear at approximately the same advanced age in humans.

Operation Sun Beam, Shot Small Boy. Project Officer's report - Project 7. 10. Spectral analysis with high-time resolution of the thermal-radiation pulse

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mahoney, J.J.; Harris, L.H.; Hennecke, H.J.

1985-09-01

The primary objective of this project was to investigate the spectral irradiance and luminosity versus time for the first thermal pulse at Shot Small Boy. This was accomplished by use of spectral filters with narrow band passes, phototubes, and magnetic tape recorders with high time resolution at two locations. The measured elapsed time to the first thermal maximum was from 50 to 110 microseconds, depending on wavelength. A graph of radiant thermal power versus time was obtained for the thermal pulse. The delineation of the first thermal pulse, especially the rise portion, is considered to be more definite than hasmore » been obtained previously. The resolution time of the instrumentation was approximately 50 microseconds. Secondary objectives were to measure the total luminosity versus time and also to measure the atmospheric attenuation. These objectives were accomplished by making measurements at two distances, 2.5 and 3.5 miles, from ground zero. In the case of the total luminosity measurements, a system of filters with a spectral transmittance approximating the sensitivity response of the average human eye was used. The results are tabulated in the report.« less

Risk factors and the outcome of therapy in patients with seizure after Carbamazepine poisoning: A two-year cross-sectional study

PubMed Central

Yaraghi, Ahmad; Eizadi-Mood, Nastaran; Salehi, Marzieh; Massoumi, Gholamreza; Zunic, Lejla; Sabzghabaee, Ali Mohammad

2015-01-01

Objective: We aimed to investigate the frequency of seizure after acute carbamazepine poisoning and the important risk factors related to the outcomes of therapy. Methods: In this two-year cross-sectional study conducted in a University Hospital in Iran, 114 patients with acute carbamazepine poisoning were divided into two groups of with seizure (n = 8) and without seizure (n = 106) after intoxication. Demographic data, average amount of drug ingestion, time elapsed from ingestion to hospital admission, history of seizure before poisoning, mental status, visual disturbances and nystagmus, duration of hospitalization, the outcomes of therapy, arterial blood gas values and serum biochemical indices were compared between the two groups. Findings: Patients with seizure had an estimated (Mean ± SD) ingestion of 14,300 ± 570 mg carbamazepine, which was significantly higher (P < 0.0001) than the seizure-free group (4600 ± 420 mg). The estimated average time between drug ingestion and hospital admission in patients with seizure and the seizure-free group were 515 ± 275 and 370 ± 46 minutes, respectively (P < 0.0001). In this study, 104 out of the total number of patients had recovered without any complication. Need for respiratory support, including airway support or intubation were the most recorded complication. One patient died after status epilepticus and aspiration pneumonia. Conclusion: The ingested amount of carbamazepine and the time elapsed from the ingestion of drug to hospital admission may influence the occurrence of seizure after acute carbamazepine poisoning; however, the outcome of supportive care in these patients seems to be positive. PMID:25710046

Active doublet method for measuring small changes in physical properties

DOEpatents

Roberts, Peter M.; Fehler, Michael C.; Johnson, Paul A.; Phillips, W. Scott

1994-01-01

Small changes in material properties of a work piece are detected by measuring small changes in elastic wave velocity and attenuation within a work piece. Active, repeatable source generate coda wave responses from a work piece, where the coda wave responses are temporally displaced. By analyzing progressive relative phase and amplitude changes between the coda wave responses as a function of elapsed time, accurate determinations of velocity and attenuation changes are made. Thus, a small change in velocity occurring within a sample region during the time periods between excitation origin times (herein called "doublets") will produce a relative delay that changes with elapsed time over some portion of the scattered waves. This trend of changing delay is easier to detect than an isolated delay based on a single arrival and provides a direct measure of elastic wave velocity changes arising from changed material properties of the work piece.

14 CFR 417.221 - Time delay analysis.

Code of Federal Regulations, 2010 CFR

2010-01-01

... OF TRANSPORTATION LICENSING LAUNCH SAFETY Flight Safety Analysis § 417.221 Time delay analysis. (a) General. A flight safety analysis must include a time delay analysis that establishes the mean elapsed time between the violation of a flight termination rule and the time when the flight safety system is...

14 CFR 417.221 - Time delay analysis.

Code of Federal Regulations, 2011 CFR

2011-01-01

... OF TRANSPORTATION LICENSING LAUNCH SAFETY Flight Safety Analysis § 417.221 Time delay analysis. (a) General. A flight safety analysis must include a time delay analysis that establishes the mean elapsed time between the violation of a flight termination rule and the time when the flight safety system is...

Measures of functional limitation as predictors of disablement in athletes with acute ankle sprains.

PubMed

Wilson, R W; Gansneder, B M

2000-09-01

Prospective multivariate design. To determine the usefulness of activity scores, self-reported athletic ability, and selected measures of physical impairment as predictors of disability duration in athletes with ankle inversion sprains. Although several measures of physical impairment and functional limitation are used to assess the consequences of injury following ankle sprain, researchers have yet to establish which measures provide the most accurate predictions of disability duration. Physical impairment, activity limitation, and disability duration were measured in 21 athletes (13 men and 8 women; mean age = 20.3 +/- 1.7 years) with acute ankle sprains. Sagittal plane ankle range of motion and volumetric displacement were used as impairment indicators. Weight-bearing activity scores (task completion count) and self-reported athletic ability (visual analog scale) were used to represent functional limitation. Elapsed time from injury to return to full athletic participation was used as the criterion measure of disability duration. The impairment measures accounted for approximately one-third of the variance in disability duration (R2 = 0.342). Adding the activity limitation measures to the regression model improved predictions of disability duration (R2 = 0.670; stepwise R2 change = 0.328). The measures of activity limitation alone, however, accounted for approximately 67% (R2 = 0.665) of the total variance in the number of days lost due to injury. Measures of activity limitation were the strongest predictors of elapsed time from injury to return to full athletic participation.

During running in place, grid cells integrate elapsed time and distance run

PubMed Central

Kraus, Benjamin J.; Brandon, Mark P.; Robinson, Robert J.; Connerney, Michael A.; Hasselmo, Michael E.; Eichenbaum, Howard

2015-01-01

Summary The spatial scale of grid cells may be provided by self-generated motion information or by external sensory information from environmental cues. To determine whether grid cell activity reflects distance traveled or elapsed time independent of external information, we recorded grid cells as animals ran in place on a treadmill. Grid cell activity was only weakly influenced by location but most grid cells and other neurons recorded from the same electrodes strongly signaled a combination of distance and time, with some signaling only distance or time. Grid cells were more sharply tuned to time and distance than non-grid cells. Many grid cells exhibited multiple firing fields during treadmill running, parallel to the periodic firing fields observed in open fields, suggesting a common mode of information processing. These observations indicate that, in the absence of external dynamic cues, grid cells integrate self-generated distance and time information to encode a representation of experience. PMID:26539893

CALCULATION OF ELAPSED DECIMAL TIME FOR DYE-TRACING STUDIES: APPLICATION OF A BASELINE TIME STANDARD (Journal Article)

EPA Science Inventory

Calculation of time of travel from dye-tracing studies in karstic aquifers is critical to establishing pollutant arrival times from points of inflow to resurgences, calculation of subsurface flow velocities, and determining other important transport parameters such as longitudin...

A subanesthetic dose of ketamine in the Rhesus monkey reduces the occurrence of anticipatory saccades.

PubMed

Ameqrane, Ilhame; Ilhame, Ameqrane; Wattiez, Nicolas; Nicolas, Wattiez; Pouget, Pierre; Pierre, Pouget; Missal, Marcus; Marcus, Missal

2015-10-01

It has been shown that antagonism of the glutamatergic N-methyl-D-aspartate (NMDA) receptor with subanesthetic doses of ketamine perturbs the perception of elapsed time. Anticipatory eye movements are based on an internal representation of elapsed time. Therefore, the occurrence of anticipatory saccades could be a particularly sensitive indicator of abnormal time perception due to NMDA receptors blockade. The objective of this study was to determine whether the occurrence of anticipatory saccades could be selectively altered by a subanesthetic dose of ketamine. Three Rhesus monkeys were trained in a simple visually guided saccadic task with a variable delay. Monkeys were rewarded for making a visually guided saccade at the end of the delay. Premature anticipatory saccades to the future position of the eccentric target initiated before the end of the delay were not rewarded. A subanesthetic dose of ketamine (0.25 mg/kg) or a saline solution of the same volume was injected i.m. during the task. We found that the injected dose of ketamine did not induce sedation or abnormal behavior. However, in ∼4 min, ketamine induced a strong reduction of the occurrence of anticipatory saccades but did not reduce the occurrence of visually guided saccades. This unexpected reduction of anticipatory saccade occurrence could be interpreted as resulting from an altered use of the perception of elapsed time during the delay period induced by NMDA receptors antagonism.

Capuchins, space, time and memory: an experimental test of what-where-when memory in wild monkeys

PubMed Central

2016-01-01

There is considerable controversy about the existence, extent and adaptive value of integrated multimodal memory in non-human animals. Building on prior results showing that wild capuchin monkeys in Argentina appear to recall both the location and amount of food at patches they had previously visited, I tested whether they also track and use elapsed time as a basis for decisions about which feeding patches to visit. I presented them with an experimental array of eight feeding sites, at each of which food rewards increased with increasing elapsed time since the previous visit, similar to the pattern of ripe fruit accumulation in natural feeding trees. Over the course of 68 days, comprising two distinct renewal rate treatments, one group repeatedly visited sites in the feeding array, generating 212 valid choices between sites. Comparison of observations against simulated movements and multinomial statistical models shows that the monkeys' choices were most consistent with dynamic memory for elapsed time specific to each of the eight sites. Thus, it appears that capuchin monkeys possess and use integrated memories of prior food patch use, including where the patch is relative to their current location, how productive the patch is and how long it has been since they last visited the patch. Natural selection to use such integrated memories in foraging tasks may provide an ecologically relevant basis for the evolution of complex intelligence in primates. PMID:27708145

Pseudoplasticity of Propellant Slurry with Varied Aluminium Content for Castability Development

NASA Astrophysics Data System (ADS)

Restasari, A.; Budi, R. S.; Hartaya, K.

2018-04-01

The modification of the percentage of aluminium is necessary to obtain certain specific impulse. But, it affects the pseudoplasticity of propellant in elapsed time that is important in casting. Therefore, this research attempts to investigate the pseudoplasticity of propellant slurry with varied aluminium contents and as time elapsed, the range of percentage of aluminium and time that allows propellant slurry to be well processed. The methods include measuring the viscosity of propellant slurries that contain 6, 8, 10, 12, 14, 16 and 18% of aluminium at varied shear rates until 40 minutes after mixing by using Brookfield viscometer. The graphs of viscosity versus shear rate were made to determine pseudoplasticity index. After that, the graph volume fraction versus pseudoplasticity index were made to be investigated. It is concluded that the more aluminium contents, the slurries with 6 to 12% aluminium contents exhibit more pseudoplastic behaviour, but the slurries with 12 to 16% aluminium exhibit less pseudoplastic. While, slurry of 18% aluminium exhibit high pseudoplasticity. In the correlation with the time, the slurry compositions of 6, 8, 14, 16% aluminium become more pseudoplastic as time elapsed. While, for compositions of 10, 12 and 18% aluminium, the trend becomes contrary. Based on the pseudoplasticity index, propellant slurries that contain 10 and 14% of aluminium are suitable for pressure casting. While for slurries with 6, 8 and 16% of aluminium are also suitable for vacuum casting. All of those suitability are possesed until 40 minutes after mixing. While, the composition of slurries that contain 12 and 18% of aluminium need to be modified to enhanced its castability.

1995 feels so close yet so far: the effect of event markers on subjective feelings of elapsed time.

PubMed

Zauberman, Gal; Levav, Jonathan; Diehl, Kristin; Bhargave, Rajesh

2010-01-01

Why does an event feel more or less distant than another event that occurred around the same time? Prior research suggests that characteristics of an event itself can affect the estimated date of its occurrence. Our work differs in that we focused on how characteristics of the time interval following an event affect people's feelings of elapsed time (i.e., their feelings of how distant an event seems). We argue that a time interval that is punctuated by a greater number of accessible intervening events related to the target event (event markers) will make the target event feel more distant, but that unrelated intervening events will not have this effect. In three studies, we found support for the systematic effect of event markers. The effect of markers was independent of other characteristics of the event, such as its memorability, emotionality, importance, and estimated date, a result suggesting that this effect is distinct from established dating biases.

Experimental study of gravitation effects in the flow of a particle-laden thin film on an inclined plane

NASA Astrophysics Data System (ADS)

Ward, Thomas; Wey, Chi; Glidden, Robert; Hosoi, A. E.; Bertozzi, A. L.

2009-08-01

The flow of viscous, particle-laden wetting thin films on an inclined plane is studied experimentally as the particle concentration is increased to the maximum packing limit. The slurry is a non-neutrally buoyant mixture of silicone oil and either solid glass beads or glass bubbles. At low concentrations (ϕ <0.45), the elapsed time versus average front position scales with the exponent predicted by Huppert [Nature (London) 300, 427 (1982)]. At higher concentrations, the average front position still scales with the exponent predicted by Huppert on some time interval, but there are observable deviations due to internal motion of the particles. At the larger concentration values and at later times, the departure from Huppert is seen to strongly depend on total slurry volume VT, inclination angle α, density difference, and particle size range.

49 CFR 178.338-9 - Holding time.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Holding time. 178.338-9 Section 178.338-9... Specifications for Containers for Motor Vehicle Transportation § 178.338-9 Holding time. (a) “Holding time” is the time, as determined by testing, that will elapse from loading until the pressure of the contents...

Space, Time, Matter:. 1918-2012

NASA Astrophysics Data System (ADS)

Veneziano, Gabriele

2013-12-01

Almost a century has elapsed since Hermann Weyl wrote his famous "Space, Time, Matter" book. After recalling some amazingly premonitory writings by him and Wolfgang Pauli in the fifties, I will try to asses the present status of the problematics they were so much concerned with.

78 FR 8390 - Procedures for the Handling of Retaliation Complaints Under the Employee Protection Provision of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-06

... elapse between the time the employer learns of the seaman's intent to report and the time the report can... the adverse action took place shortly after protected activity, giving rise to the inference that it...

Odometers for Rail Application

DOT National Transportation Integrated Search

1975-05-01

Available mileage counters were evaluated, anticipating the possibility of using mileage intervals, rather than elapsed time, for freight car inspection. Simple, reliable and reasonably low costing devices were required. Only two unpowered mileage co...

Time to Criterion: An Experimental Study.

ERIC Educational Resources Information Center

Anderson, Lorin W.

The purpose of the study was to investigate the magnitude of individual differences in time-to-criterion and the stability of these differences. Time-to-criterion was defined in two ways: the amount of elapsed time required to attain the criterion level and the amount of on-task time required to attain the criterion level. Ninety students were…

Apical root resorption in orthodontically treated adults.

PubMed

Baumrind, S; Korn, E L; Boyd, R L

1996-09-01

This study analyzed the relationship in orthodontically treated adults between upper central incisor displacement measured on lateral cephalograms and apical root resorption measured on anterior periapical x-ray films. A multiple linear regression examined incisor displacements in four directions (retraction, advancement, intrusion, and extrusion) as independent variables, attempting to account for observed differences in the dependent variable, resorption. Mean apical resorption was 1.36 mm (sd +/- 1.46, n = 73). Mean horizontal displacement of the apex was -0.83 mm (sd +/- 1.74, n = 67); mean vertical displacement was 0.19 mm (sd +/- 1.48, n = 67). The regression coefficients for the intercept and for retraction were highly significant; those for extrusion, intrusion, and advancement were not. At the 95% confidence level, an average of 0.99 mm (se = +/- 0.34) of resorption was implied in the absence of root displacement and an average of 0.49 mm (se = +/- 0.14) of resorption was implied per millimeter of retraction. R2 for all four directional displacement variables (DDVs) taken together was only 0.20, which implied that only a relatively small portion of the observed apical resorption could be accounted for by tooth displacement alone. In a secondary set of univariate analyses, the associations between apical resorption and each of 14 additional treatment-related variables were examined. Only Gender, Elapsed Time, and Total Apical Displacement displayed statistically significant associations with apical resorption. Additional multiple regressions were then performed in which the data for each of these three statistically significant variables were considered separately, with the data for the four directional displacement variables. The addition of information on Elapsed Time or Total Apical Displacement did not explain a significant additional portion of the variability in apical resorption. On the other hand, the addition of information on Gender to the information on the four directional displacement variables yielded an R2 value of 0.35, which indicated that these variables taken together could account for approximately a third of the observed variability in apical resorption in this sample.

Response of lamb plasma carotenoid concentration to a shift from a low to a high dietary carotenoid level.

PubMed

de Oliveira, L; Carvalho, P C F; Prache, S

2012-07-01

This study was conducted to investigate the pattern of plasma carotenoid concentration (PCC) in lambs switching from a low to a high dietary carotenoid level. A total of 12 Romane lambs were individually penned indoors and fed a low dietary carotenoid level for 23 days (period 1) and then a high dietary carotenoid level for 15 days (period 2). At the beginning of period 2, the lambs were 15 weeks old and weighed 29.9 kg (s.d. 2.7) on average. Lambs were fed daily (dry matter) 0.558 kg alfalfa pellets, 0.181 kg straw and 0.181 kg barley. Plasma content of total carotenoids was measured daily in period 2 by spectrophotometry. PCC (μg/l) varied with the animal (P < 0.001) and with time elapsed since the beginning of alfalfa distribution (P < 0.001). Mean PCC was 8 μg/l (s.d. 3.3) at the beginning of period 2, then increased curvilinearly with the time elapsed since the beginning of alfalfa distribution. As early as 24 h on the alfalfa diet, PCC was already higher than before the switch (P < 0.001). Mean PCC continued to increase until day 6 on average and reached a plateau thereafter. We propose a monomolecular function to model this pattern, the equation obtained on the mean data being: PCC = 97 (s.e. 2.2) × (1-exp(-0.3378 (s.e. 0.0282)×d)), where r2 = 0.997, r.s.d. = 4.47, n = 15 and d = day. The percentage of variance explained by the model ranged between 95.9% and 99.2%, depending on the animal. The parameters of the monomolecular function varied among animals, confirming the interindividual variability in animal response. Plateau for PCC was reached slightly earlier for the six lambs with the lowest values of the asymptote than for the six lambs with the highest values of the asymptote.

Tracking the dispersion of Scaphoideus titanus Ball (Hemiptera: Cicadellidae) from wild to cultivated grapevine: use of a novel mark-capture technique.

PubMed

Lessio, F; Tota, F; Alma, A

2014-08-01

The dispersion of Scaphoideus titanus Ball adults from wild to cultivated grapevines was studied using a novel mark-capture technique. The crowns of wild grapevines located at a distance from vineyards ranging from 5 to 330 m were sprayed with a water solution of either cow milk (marker: casein) or chicken egg whites (marker: albumin) and insects captured in yellow sticky traps placed on the canopy of grapes were analyzed via an indirect ELISA for markers' identification. Data were subject to exponential regression as a function of distance from wild grapevine, and to spatial interpolation (Inverse Distance Weighted and Kernel interpolation with barriers) using ArcGIS Desktop 10.1 software. The influence of rainfall and time elapsed after marking on markers' effectiveness, and the different dispersion of males and females were studied with regression analyses. Of a total of 5417 insects analyzed, 43% were positive to egg; whereas 18% of 536 tested resulted marked with milk. No influence of rainfall or time elapsed was observed for egg, whereas milk was affected by time. Males and females showed no difference in dispersal. Marked adults decreased exponentially along with distance from wild grapevine and up to 80% of them were captured within 30 m. However, there was evidence of long-range dispersal up to 330 m. The interpolation maps showed a clear clustering of marked S. titanus close to the treated wild grapevine, and the pathways to the vineyards did not always seem to go along straight lines but mainly along ecological corridors. S. titanus adults are therefore capable of dispersing from wild to cultivated grapevine, and this may affect pest management strategies.

How to Be Proactive About Interference: Lessons From Animal Memory

PubMed Central

Wright, Anthony A.; Katz, Jeffrey S.; Ma, Wei Ji

2015-01-01

Processes of proactive interference were explored using the pigeon as a model system of memory. This study shows that proactive interference extends back in time at least 16 trials (and as many minutes), revealing a continuum of interference and providing a framework for studying memory. Pigeons were tested in a delayed same/different task containing trial-unique pictures. On interference trials, sample pictures from previous trials reappeared as test pictures on different trials. Proactive-interference functions showed greatest interference from the most recent trial and with the longer of two delays (10 s vs. 1 s). These interference functions are accounted for by a time-estimation model based on signal detection theory. The model predicts that accuracy at test is determined solely by the ratio of the elapsed time since the offset of the current-trial sample to the elapsed time since the offset of the interfering sample. Implications for comparing memory of different species and different types of memory (e.g., familiarity vs. recollection) are discussed. PMID:22491142

How to be proactive about interference: lessons from animal memory.

PubMed

Wright, Anthony A; Katz, Jeffrey S; Ma, Wei Ji

2012-05-01

Processes of proactive interference were explored using the pigeon as a model system of memory. This study shows that proactive interference extends back in time at least 16 trials (and as many minutes), revealing a continuum of interference and providing a framework for studying memory. Pigeons were tested in a delayed same/different task containing trial-unique pictures. On interference trials, sample pictures from previous trials reappeared as test pictures on different trials. Proactive-interference functions showed greatest interference from the most recent trial and with the longer of two delays (10 s vs. 1 s). These interference functions are accounted for by a time-estimation model based on signal detection theory. The model predicts that accuracy at test is determined solely by the ratio of the elapsed time since the offset of the current-trial sample to the elapsed time since the offset of the interfering sample. Implications for comparing memory of different species and different types of memory (e.g., familiarity vs. recollection) are discussed.

A global meta-analysis on the ecological drivers of forest restoration success

PubMed Central

Crouzeilles, Renato; Curran, Michael; Ferreira, Mariana S.; Lindenmayer, David B.; Grelle, Carlos E. V.; Rey Benayas, José M.

2016-01-01

Two billion ha have been identified globally for forest restoration. Our meta-analysis encompassing 221 study landscapes worldwide reveals forest restoration enhances biodiversity by 15–84% and vegetation structure by 36–77%, compared with degraded ecosystems. For the first time, we identify the main ecological drivers of forest restoration success (defined as a return to a reference condition, that is, old-growth forest) at both the local and landscape scale. These are as follows: the time elapsed since restoration began, disturbance type and landscape context. The time elapsed since restoration began strongly drives restoration success in secondary forests, but not in selectively logged forests (which are more ecologically similar to reference systems). Landscape restoration will be most successful when previous disturbance is less intensive and habitat is less fragmented in the landscape. Restoration does not result in full recovery of biodiversity and vegetation structure, but can complement old-growth forests if there is sufficient time for ecological succession. PMID:27193756

Alkali ocular burns in Martinique (French West Indies) Evaluation of the use of an amphoteric solution as the rinsing product.

PubMed

Merle, Harold; Donnio, Angélique; Ayeboua, Lucas; Michel, Franck; Thomas, Félix; Ketterle, Jeannine; Leonard, Christian; Josset, Patrice; Gerard, Max

2005-03-01

During the 4 years of this study, we noted 66 cases of alkali ocular burns, or approximately 16 cases per year, nearly half (45.5%) of which are due to an assault. For grade 1 and 2 burns the time elapsed to reepithelialization appears to be shorter when rinsed with Diphoterine* versus physiological solution. Comparison of the effectiveness of two rinsing solutions for emergency use: a physiological solution and an amphoteric solution (Diphoterine*, Laboratories Prevor, Valmondois, France). Description of the clinical and progressive characteristics of alkali burns treated at the University Hospital Center of Fort de France in Martinique (French West Indies). Prospective consecutive observational case series and nonrandomized comparative study. Sixty-six patients were included. The total number of burned eyes is 104. Forty-eight eyes (46%) were rinsed with physiological solution and 56 eyes (54%) with Diphoterine*. All patients benefited from an ocular rinse with 500ml of physiological solution or Diphoterine*, followed by a complete ophthalmologic exam. The ocular injuries were classified according to the Roper-Hall modification of the Hughes classification system. The same standardized therapeutic protocol was applied and adapted to the seriousness of the burn. Demographic data, time to corneal reepithelialization, final best corrected visual acuity and complications were analysed. Twenty-eight (42.4%) patients have a unilateral burn and 38 (57.6%) patients have bilateral burns. In decreasing order of frequency, the circumstances surrounding the injury are: assaults in 45.5% of cases (n=30), work-related accidents in 32% of cases (n=31), and domestic accidents in 23% of cases (n=15). For grade 1 and 2 burns the time elapsed to reepithelialization appears to be shorter when rinsed with Diphoterine* versus physiological solution (respectively): 1.9+/-1 days versus 11.1+/-1.4 days (p=10(-7)) and 5.6+/-4.9 days versus 10+/-9.2 days (p=0.02). For grade 3 and 4 burns, there are complications in 11 cases (11.6%): 8 corneal opacities and 3 perforations. This study is the first conducted in humans that takes into account the type of ocular rinse product used in the progressive follow-up study of injuries. The time elapsed to reepithelialization is shorter with Diphoterine* for grade 1 and 2 burns. There are not enough cases of grade 3 and 4 burns to make a conclusion. Diphoterine* seems very effective in terms of its mechanism of action and the experimental and clinical results.

Evaluation of digital dental models obtained from dental cone-beam computed tomography scan of alginate impressions

PubMed Central

Jiang, Tingting; Lee, Sang-Mi; Hou, Yanan; Chang, Xin

2016-01-01

Objective To investigate the dimensional accuracy of digital dental models obtained from the dental cone-beam computed tomography (CBCT) scan of alginate impressions according to the time elapse when the impressions are stored under ambient conditions. Methods Alginate impressions were obtained from 20 adults using 3 different alginate materials, 2 traditional alginate materials (Alginoplast and Cavex Impressional) and 1 extended-pour alginate material (Cavex ColorChange). The impressions were stored under ambient conditions, and scanned by CBCT immediately after the impressions were taken, and then at 1 hour intervals for 6 hours. After reconstructing three-dimensional digital dental models, the models were measured and the data were analyzed to determine dimensional changes according to the elapsed time. The changes within the measurement error were regarded as clinically acceptable in this study. Results All measurements showed a decreasing tendency with an increase in the elapsed time after the impressions. Although the extended-pour alginate exhibited a less decreasing tendency than the other 2 materials, there were no statistically significant differences between the materials. Changes above the measurement error occurred between the time points of 3 and 4 hours after the impressions. Conclusions The results of this study indicate that digital dental models can be obtained simply from a CBCT scan of alginate impressions without sending them to a remote laboratory. However, when the impressions are not stored under special conditions, they should be scanned immediately, or at least within 2 to 3 hours after the impressions are taken. PMID:27226958

Crime seriousness and participation in restorative justice: The role of time elapsed since the offense.

PubMed

Zebel, Sven; Schreurs, Wendy; Ufkes, Elze G

2017-08-01

Restorative justice policies and programs aimed at facilitating victim-offender mediation (VOM) are part of many criminal justice systems around the world. Given its voluntary nature and potential for positive outcomes, the appropriateness and feasibility of VOM after serious offenses is subject to debate in the literature. In light of this discussion, this study first aimed to unravel the prevalence of serious offenses in cases registered for VOM and examined whether crime seriousness predicts whether mediated contact is reached between victims and offenders. Second, it tested the hypothesis that victims of increasingly serious, harmful crimes are more willing to participate when more time has elapsed since the offense-in contrast to victims of less serious, harmful crimes. We analyzed 199 cases registered for VOM in the Netherlands and coded the perceived wrongfulness, harmfulness, and average duration of incarceration of an offense as 3 distinct indicators of crime seriousness in these cases. The findings revealed that cases registered for VOM (a) are, in terms of the incarceration duration, on average more serious than all offenses in the population, and (b) resulted in mediated contact (or not) independently of the 3 seriousness indicators. In addition, empirical support was found for the hypothesis that victims' willingness to participate in VOM increased over time after more harmful offenses, whereas it decreased when offenses inflicted less harm. These findings suggest that when VOM programs operate irrespectively of the time elapsed after crime, mediated contact between parties may be as likely after minor and serious offenses. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Flight data file: STS-4 crew activity plan

NASA Technical Reports Server (NTRS)

Pippert, E. B., Jr.

1982-01-01

The STS-4 Crew Activity Plan contains the on-orbit timeline, which is a flight data file article. Various time scales such as Mission Elapsed Time (MET), Greenwich Mean Time (GMT), and time until deorbit ignition as well as crew activities, day/night, orbit position, ground tracking, communication coverage, attitude, and maneuvers are presented in chart form.

On the Run-Time Optimization of the Boolean Logic of a Program.

ERIC Educational Resources Information Center

Cadolino, C.; Guazzo, M.

1982-01-01

Considers problem of optimal scheduling of Boolean expression (each Boolean variable represents binary outcome of program module) on single-processor system. Optimization discussed consists of finding operand arrangement that minimizes average execution costs representing consumption of resources (elapsed time, main memory, number of…

East Oklahoma forests

Treesearch

Herbert S. Sternitzke; Charles C. van Sickle

1968-01-01

The 17 counties designated as east Oklahoma in this report encompass the main belt of commercial timberland in the State (fig. 1). Forests occupy 5.5 million acres or some 57 percent of the total land area. During the decade that elapsed between the 1956 and 1966 surveys, the acreage of forest land declined about 5 percent. The modest drop in forest area was largely...

Kernel analysis of partial least squares (PLS) regression models.

PubMed

Shinzawa, Hideyuki; Ritthiruangdej, Pitiporn; Ozaki, Yukihiro

2011-05-01

An analytical technique based on kernel matrix representation is demonstrated to provide further chemically meaningful insight into partial least squares (PLS) regression models. The kernel matrix condenses essential information about scores derived from PLS or principal component analysis (PCA). Thus, it becomes possible to establish the proper interpretation of the scores. A PLS model for the total nitrogen (TN) content in multiple Thai fish sauces is built with a set of near-infrared (NIR) transmittance spectra of the fish sauce samples. The kernel analysis of the scores effectively reveals that the variation of the spectral feature induced by the change in protein content is substantially associated with the total water content and the protein hydration. Kernel analysis is also carried out on a set of time-dependent infrared (IR) spectra representing transient evaporation of ethanol from a binary mixture solution of ethanol and oleic acid. A PLS model to predict the elapsed time is built with the IR spectra and the kernel matrix is derived from the scores. The detailed analysis of the kernel matrix provides penetrating insight into the interaction between the ethanol and the oleic acid.

Modern trends in Class III orthognathic treatment: A time series analysis.

PubMed

Lee, Chang-Hoon; Park, Hyun-Hee; Seo, Byoung-Moo; Lee, Shin-Jae

2017-03-01

To examine the current trends in surgical-orthodontic treatment for patients with Class III malocclusion using time-series analysis. The records of 2994 consecutive patients who underwent orthognathic surgery from January 1, 2004, through December 31, 2015, at Seoul National University Dental Hospital, Seoul, Korea, were reviewed. Clinical data from each surgical and orthodontic treatment record included patient's sex, age at the time of surgery, malocclusion classification, type of orthognathic surgical procedure, place where the orthodontic treatment was performed, orthodontic treatment modality, and time elapsed for pre- and postoperative orthodontic treatment. Out of the orthognathic surgery patients, 86% had Class III malocclusion. Among them, two-jaw surgeries have become by far the most common orthognathic surgical treatment these days. The age at the time of surgery and the number of new patients had seasonal variations, which demonstrated opposing patterns. There was neither positive nor negative correlation between pre- and postoperative orthodontic treatment time. Elapsed orthodontic treatment time for both before and after Class III orthognathic surgeries has been decreasing over the years. Results of the time series analysis might provide clinicians with some insights into current surgical and orthodontic management.

KSC-07pd3170

NASA Image and Video Library

2007-11-07

KENNEDY SPACE CENTER, FLA. -- After space shuttle Discovery's landing at NASA's Kennedy Space Center, workers transfer experiments to vehicles. Discovery completed a 15-day mission to the International Space Station with a smooth landing on Runway 33. Main gear touchdown was 1:01:16 p.m. Wheel stop was at 1:02:07 p.m. Mission elapsed time was 15 days, 2 hours, 24 minutes and 2 seconds. The crew completed a 15-day mission to the International Space Station with a smooth landing on Runway 33. Main gear touchdown was 1:01:16 p.m. Wheel stop was at 1:02:07 p.m. Mission elapsed time was 15 days, 2 hours, 24 minutes and 2 seconds. Mission STS-120 continued the construction of the station with the installation of the Harmony Node 2 module and the relocation of the P6 truss. Photo credit: NASA/Jim Grossmann

Early marriage, rape, child prostitution, and related factors determining the psychosocial effects severity of child sexual abuse in Ethiopia.

PubMed

Wondie, Yemataw; Zemene, Workie; Reschke, Konrad; Schröder, Harry

2011-05-01

This study was aimed at identifying factors that determine the psychosocial effects severity of child sexual abuse. Data were collected from 318 female children in Ethiopia using the Children's Impact of Traumatic Events Scale-Revised and the Rosenberg Self-Esteem Scale. The results revealed that respondents who survived rape and child prostitution were more symptomatic than those who were married early. Respondents for whom less time had elapsed since their first experience of abuse demonstrated a significantly higher level of post-traumatic stress disorder symptoms, negative reactions by others, self-blame, and guilt than those for whom more time had elapsed since such an experience. The respondents in an intact marital relationship were found to be less symptomatic than their never married and divorced counterparts. Implications for intervention and further investigations are discussed.

Effects of videogame distraction using a virtual reality type head-mounted display helmet on cold pressor pain in children.

PubMed

Dahlquist, Lynnda M; Weiss, Karen E; Clendaniel, Lindsay Dillinger; Law, Emily F; Ackerman, Claire Sonntag; McKenna, Kristine D

2009-06-01

To test whether a head-mounted display helmet enhances the effectiveness of videogame distraction for children experiencing cold pressor pain. Forty-one children, aged 6-14 years, underwent one or two baseline cold pressor trials followed by two distraction trials in which they played the same videogame with and without the helmet in counterbalanced order. Pain threshold (elapsed time until the child reported pain) and pain tolerance (total time the child kept the hand submerged in the cold water) were measured for each cold pressor trial. Both distraction conditions resulted in improved pain tolerance relative to baseline. Older children appeared to experience additional benefits from using the helmet, whereas younger children benefited equally from both conditions. The findings suggest that virtual reality technology can enhance the effects of distraction for some children. Research is needed to identify the characteristics of children for whom this technology is best suited.

Finite element solution of optimal control problems with inequality constraints

NASA Technical Reports Server (NTRS)

Bless, Robert R.; Hodges, Dewey H.

1990-01-01

A finite-element method based on a weak Hamiltonian form of the necessary conditions is summarized for optimal control problems. Very crude shape functions (so simple that element numerical quadrature is not necessary) can be used to develop an efficient procedure for obtaining candidate solutions (i.e., those which satisfy all the necessary conditions) even for highly nonlinear problems. An extension of the formulation allowing for discontinuities in the states and derivatives of the states is given. A theory that includes control inequality constraints is fully developed. An advanced launch vehicle (ALV) model is presented. The model involves staging and control constraints, thus demonstrating the full power of the weak formulation to date. Numerical results are presented along with total elapsed computer time required to obtain the results. The speed and accuracy in obtaining the results make this method a strong candidate for a real-time guidance algorithm.

The effects of simulated fog and motion on simulator sickness in a driving simulator and the duration of after-effects.

PubMed

Dziuda, Lukasz; Biernacki, Marcin P; Baran, Paulina M; Truszczyński, Olaf E

2014-05-01

In the study, we checked: 1) how the simulator test conditions affect the severity of simulator sickness symptoms; 2) how the severity of simulator sickness symptoms changes over time; and 3) whether the conditions of the simulator test affect the severity of these symptoms in different ways, depending on the time that has elapsed since the performance of the task in the simulator. We studied 12 men aged 24-33 years (M = 28.8, SD = 3.26) using a truck simulator. The SSQ questionnaire was used to assess the severity of the symptoms of simulator sickness. Each of the subjects performed three 30-minute tasks running along the same route in a driving simulator. Each of these tasks was carried out in a different simulator configuration: A) fixed base platform with poor visibility; B) fixed base platform with good visibility; and C) motion base platform with good visibility. The measurement of the severity of the simulator sickness symptoms took place in five consecutive intervals. The results of the analysis showed that the simulator test conditions affect in different ways the severity of the simulator sickness symptoms, depending on the time which has elapsed since performing the task on the simulator. The simulator sickness symptoms persisted at the highest level for the test conditions involving the motion base platform. Also, when performing the tasks on the motion base platform, the severity of the simulator sickness symptoms varied depending on the time that had elapsed since performing the task. Specifically, the addition of motion to the simulation increased the oculomotor and disorientation symptoms reported as well as the duration of the after-effects. Copyright © 2013 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Separation of circadian and wake duration-dependent modulation of EEG activation during wakefulness

NASA Technical Reports Server (NTRS)

Cajochen, C.; Wyatt, J. K.; Czeisler, C. A.; Dijk, D. J.

2002-01-01

The separate contribution of circadian rhythmicity and elapsed time awake on electroencephalographic (EEG) activity during wakefulness was assessed. Seven men lived in an environmental scheduling facility for 4 weeks and completed fourteen 42.85-h 'days', each consisting of an extended (28.57-h) wake episode and a 14.28-h sleep opportunity. The circadian rhythm of plasma melatonin desynchronized from the 42.85-h day. This allowed quantification of the separate contribution of circadian phase and elapsed time awake to variation in EEG power spectra (1-32 Hz). EEG activity during standardized behavioral conditions was markedly affected by both circadian phase and elapsed time awake in an EEG frequency- and derivation-specific manner. The nadir of the circadian rhythm in alpha (8-12 Hz) activity in both fronto-central and occipito-parietal derivations occurred during the biological night, close to the crest of the melatonin rhythm. The nadir of the circadian rhythm of theta (4.5-8 Hz) and beta (20-32 Hz) activity in the fronto-central derivation was located close to the onset of melatonin secretion, i.e. during the wake maintenance zone. As time awake progressed, delta frequency (1-4.5 Hz) and beta (20-32 Hz) activity rose monotonically in frontal derivations. The interaction between the circadian and wake-dependent increase in frontal delta was such that the intrusion of delta was minimal when sustained wakefulness coincided with the biological day, but pronounced during the biological night. Our data imply that the circadian pacemaker facilitates frontal EEG activation during the wake maintenance zone, by generating an arousal signal that prevents the intrusion of low-frequency EEG components, the propensity for which increases progressively during wakefulness.

Wait Times Experienced by Lung Cancer Patients in the BC Southern Interior to Obtain Oncologic Care: Exploration of the Intervals from First Abnormal Imaging to Oncologic Treatment

PubMed Central

Chowdhury, Rezwan; Boyce, Andrew; Halperin, Ross

2015-01-01

Background: Lung cancer is associated with rapid disease progression, which can significantly progress over a duration of four to eight weeks. This study examines the time interval lung cancer patients from the interior of British Columbia (BC) experience while undergoing diagnostic evaluation, biopsy, staging, and preparation for treatment. Methods: A chart review of lung cancer patients (n=231) referred to the BC Cancer Agency Centre for the Southern Interior between January 1, 2010 and December 31, 2011 was performed. Time zero was defined as the date of the first abnormal chest imaging. Time intervals, expressed as median averages, to specialist consult, biopsy, oncologic referral, initial oncology consultation, and commencement of oncologic treatment were obtained. Results: The median time interval from first abnormal chest imaging to a specialist consultation was 18 days (interquartile range, IQR, 7-36). An additional nine days elapsed prior to biopsy in the form of bronchoscopy, CT-guided biopsy, or sputum cytology (median; IQR, 3-21); if lobectomy was required, 18 days elapsed (median; IQR, 9-28). Eight days were required for pathologic diagnosis and subsequent referral to the cancer centre (median; IQR, 3-16.5). Once referral was received, 10 days elapsed prior to consultation with either a medical or radiation oncologist (median, IQR 5-18). Finally, eight days was required for initiation of radiation and/or chemotherapy (median; IQR, 1-15). The median wait time from detection of lung cancer on imaging to oncologic treatment in the form of radiation and/or chemotherapy was 65.5 days (IQR, 41.5-104.3).  Interpretation: Patients in the BC Southern Interior experience considerable delays in accessing lung cancer care. During this time, the disease has the potential to significantly progress and it is possible that a subset of patients may lose their opportunity for curative intent treatment. PMID:26543688

Near real-time vaccine safety surveillance with partially accrued data.

PubMed

Greene, Sharon K; Kulldorff, Martin; Yin, Ruihua; Yih, W Katherine; Lieu, Tracy A; Weintraub, Eric S; Lee, Grace M

2011-06-01

The Vaccine Safety Datalink (VSD) Project conducts near real-time vaccine safety surveillance using sequential analytic methods. Timely surveillance is critical in identifying potential safety problems and preventing additional exposure before most vaccines are administered. For vaccines that are administered during a short period, such as influenza vaccines, timeliness can be improved by undertaking analyses while risk windows following vaccination are ongoing and by accommodating predictable and unpredictable data accrual delays. We describe practical solutions to these challenges, which were adopted by the VSD Project during pandemic and seasonal influenza vaccine safety surveillance in 2009/2010. Adjustments were made to two sequential analytic approaches. The Poisson-based approach compared the number of pre-defined adverse events observed following vaccination with the number expected using historical data. The expected number was adjusted for the proportion of the risk window elapsed and the proportion of inpatient data estimated to have accrued. The binomial-based approach used a self-controlled design, comparing the observed numbers of events in risk versus comparison windows. Events were included in analysis only if they occurred during a week that had already passed for both windows. Analyzing data before risk windows fully elapsed improved the timeliness of safety surveillance. Adjustments for data accrual lags were tailored to each data source and avoided biasing analyses away from detecting a potential safety problem, particularly early during surveillance. The timeliness of vaccine and drug safety surveillance can be improved by properly accounting for partially elapsed windows and data accrual delays. Copyright © 2011 John Wiley & Sons, Ltd.

ELAPSE - NASA AMES LISP AND ADA BENCHMARK SUITE: EFFICIENCY OF LISP AND ADA PROCESSING - A SYSTEM EVALUATION

NASA Technical Reports Server (NTRS)

Davis, G. J.

1994-01-01

One area of research of the Information Sciences Division at NASA Ames Research Center is devoted to the analysis and enhancement of processors and advanced computer architectures, specifically in support of automation and robotic systems. To compare systems' abilities to efficiently process Lisp and Ada, scientists at Ames Research Center have developed a suite of non-parallel benchmarks called ELAPSE. The benchmark suite was designed to test a single computer's efficiency as well as alternate machine comparisons on Lisp, and/or Ada languages. ELAPSE tests the efficiency with which a machine can execute the various routines in each environment. The sample routines are based on numeric and symbolic manipulations and include two-dimensional fast Fourier transformations, Cholesky decomposition and substitution, Gaussian elimination, high-level data processing, and symbol-list references. Also included is a routine based on a Bayesian classification program sorting data into optimized groups. The ELAPSE benchmarks are available for any computer with a validated Ada compiler and/or Common Lisp system. Of the 18 routines that comprise ELAPSE, provided within this package are 14 developed or translated at Ames. The others are readily available through literature. The benchmark that requires the most memory is CHOLESKY.ADA. Under VAX/VMS, CHOLESKY.ADA requires 760K of main memory. ELAPSE is available on either two 5.25 inch 360K MS-DOS format diskettes (standard distribution) or a 9-track 1600 BPI ASCII CARD IMAGE format magnetic tape. The contents of the diskettes are compressed using the PKWARE archiving tools. The utility to unarchive the files, PKUNZIP.EXE, is included. The ELAPSE benchmarks were written in 1990. VAX and VMS are trademarks of Digital Equipment Corporation. MS-DOS is a registered trademark of Microsoft Corporation.

75 FR 70707 - Detroit Edison Company; Environmental Assessment and Finding of No Significant Impact

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-18

... extend the time period that can elapse during shipments of low-level radioactive waste before the... extend the time period for the licensee to receive acknowledgment that the low-level radioactive waste...-level radioactive waste are not acknowledged by the intended recipient within 20 days after transfer to...

47 CFR 2.1055 - Measurements required: Frequency stability.

Code of Federal Regulations, 2011 CFR

2011-10-01

... not more than 10° centigrade through the range. A period of time sufficient to stabilize all of the... incorporating heater type crystal oscillators to be used in mobile stations, for which type acceptance is first... from a cold start and the elapsed time necessary for the frequency to stabilize within the applicable...

47 CFR 2.1055 - Measurements required: Frequency stability.

Code of Federal Regulations, 2010 CFR

2010-10-01

... not more than 10° centigrade through the range. A period of time sufficient to stabilize all of the... incorporating heater type crystal oscillators to be used in mobile stations, for which type acceptance is first... from a cold start and the elapsed time necessary for the frequency to stabilize within the applicable...

47 CFR 2.1055 - Measurements required: Frequency stability.

Code of Federal Regulations, 2012 CFR

2012-10-01

... not more than 10° centigrade through the range. A period of time sufficient to stabilize all of the... incorporating heater type crystal oscillators to be used in mobile stations, for which type acceptance is first... from a cold start and the elapsed time necessary for the frequency to stabilize within the applicable...

47 CFR 2.1055 - Measurements required: Frequency stability.

Code of Federal Regulations, 2014 CFR

2014-10-01

... not more than 10° centigrade through the range. A period of time sufficient to stabilize all of the... incorporating heater type crystal oscillators to be used in mobile stations, for which type acceptance is first... from a cold start and the elapsed time necessary for the frequency to stabilize within the applicable...

47 CFR 2.1055 - Measurements required: Frequency stability.

Code of Federal Regulations, 2013 CFR

2013-10-01

... not more than 10° centigrade through the range. A period of time sufficient to stabilize all of the... incorporating heater type crystal oscillators to be used in mobile stations, for which type acceptance is first... from a cold start and the elapsed time necessary for the frequency to stabilize within the applicable...

Route profile analysis system and method

DOEpatents

Mullenhoff, Donald J.; Wilson, Stephen W.

1986-01-01

A system for recording terrain profile information is disclosed. The system accurately senses incremental distances traveled by a vehicle along with vehicle inclination, recording both with elapsed time. The incremental distances can subsequently be differentiated with respect to time to obtain acceleration. The acceleration can then be used by the computer to correct the sensed inclination.

Route profile analysis system and method

DOEpatents

Mullenhoff, D.J.; Wilson, S.W.

1982-07-29

A system for recording terrain profile information is disclosed. The system accurately senses incremental distances traveled by a vehicle along with vehicle inclination, recording both with elapsed time. The incremental distances can subsequently be differentiated with respect to time to obtain acceleration. The computer acceleration can then be used to correct the sensed inclination.

Science and Engineering Doctorate Production among Minorities with Non-Traditional Backgrounds.

ERIC Educational Resources Information Center

Brazziel, William F.; Brazziel, Marian E.

This study examined the extent to which minority individuals with baccalaureate origins as non-traditional students (baccalaureates completed at age 25 or over) completed doctoral degrees in science and engineering. It compared the efficacy of their degree completion, i.e., elapsed time and registered time to degree, with that of counterparts with…

A model for discriminating reinforcers in time and space.

PubMed

Cowie, Sarah; Davison, Michael; Elliffe, Douglas

2016-06-01

Both the response-reinforcer and stimulus-reinforcer relation are important in discrimination learning; differential responding requires a minimum of two discriminably-different stimuli and two discriminably-different associated contingencies of reinforcement. When elapsed time is a discriminative stimulus for the likely availability of a reinforcer, choice over time may be modeled by an extension of the Davison and Nevin (1999) model that assumes that local choice strictly matches the effective local reinforcer ratio. The effective local reinforcer ratio may differ from the obtained local reinforcer ratio for two reasons: Because the animal inaccurately estimates times associated with obtained reinforcers, and thus incorrectly discriminates the stimulus-reinforcer relation across time; and because of error in discriminating the response-reinforcer relation. In choice-based timing tasks, the two responses are usually highly discriminable, and so the larger contributor to differences between the effective and obtained reinforcer ratio is error in discriminating the stimulus-reinforcer relation. Such error may be modeled either by redistributing the numbers of reinforcers obtained at each time across surrounding times, or by redistributing the ratio of reinforcers obtained at each time in the same way. We assessed the extent to which these two approaches to modeling discrimination of the stimulus-reinforcer relation could account for choice in a range of temporal-discrimination procedures. The version of the model that redistributed numbers of reinforcers accounted for more variance in the data. Further, this version provides an explanation for shifts in the point of subjective equality that occur as a result of changes in the local reinforcer rate. The inclusion of a parameter reflecting error in discriminating the response-reinforcer relation enhanced the ability of each version of the model to describe data. The ability of this class of model to account for a range of data suggests that timing, like other conditional discriminations, is choice under the joint discriminative control of elapsed time and differential reinforcement. Understanding the role of differential reinforcement is therefore critical to understanding control by elapsed time. Copyright © 2016 Elsevier B.V. All rights reserved.

Late diagnosis and surgical treatment of patients diagnosed with unilateral congenital cataract at Fundación Visión, in Asuncion, Paraguay.

PubMed

Zegarra, Manuel; Burga, Gisella Harumi; Lansingh, Van; Samudio, Margarita; Duarte, Edgar; Ferreira, Rocio; Dorantes, Yesenia; Ginés, Juan Carlos; Zepeda, Luz

2014-10-01

Purpose: Providing data on the late diagnosis and surgical treatment of patients who underwent surgery for total unilateral congenital cataract. Methods: Systematic retrospective review of the medical record of all patients between 0 and 16 years old with total unilateral congenital cataract who underwent surgery at Fundación Vision between January 2010 and July 2012. Results: Medical records of 37 patients (51 % females) were studied, age was 7.4 (± 4.9) years (average ± SD) and 62% lived on Departamento Central (the most populated region from Paraguay). A total of 97.3% patients underwent late surgical treatment and 86.5% received a late diagnosis. The average time elapsed between the diagnosis and the surgical treatment was one month, and 62.2% of the patients underwent surgery within six months from the diagnosis. Conclusion: This study evidences that most of the patients in our series had a late treatment as a result of a late diagnosis. Based on these results we recommend establishing strategies to improve the early detection and surgical treatment of the newborns.

Animal cognition: an insect's sense of time?

PubMed

Skorupski, Peter; Chittka, Lars

2006-10-10

For Immanuel Kant, time was the very form of the inner sense, the bedrock of our consciousness and also the origin of arithmetic ability. New research on bumblebees has shown that even an invertebrate with a brain the size of a pinhead can actively sense the passage of elapsed time, allowing it to predict when certain salient events will occur in the future.

The investigation of vertebral injury sustained during aircrew ejection

NASA Technical Reports Server (NTRS)

Benedict, J. V.

1972-01-01

A series of tests were performed on excised human vertebral segments to determine the static and dynamic response of the thoraco-lumbar spine when loaded in flexion. A total of fifteen tests were performed on eleven specimens. Specimens were obtained from male donors ranging in age from 34 to 60 years. Demographic data pertinent to each specimen and the elapsed time between death of the donor and testing of each corresponding specimen are presented. Only spinal segments comprised of lower thoracic and upper lumbar vertebrae were tested because in aircraft ejection injuries clinical complications in this anatomical region predominate. A complex continuum mathematical model describing the dynamic response of the human spine was formulated, solved, and verified experimentally. Detailed results are presented in figures, tables, and equations.

29 CFR 95.22 - Payment.

Code of Federal Regulations, 2014 CFR

2014-07-01

... and Human Services, Payment Management System, P.O. Box 6021, Rockville, MD 20852. Interest amounts up... FOREIGN GOVERNMENTS, AND INTERNATIONAL ORGANIZATIONS Post-Award Requirements Financial and Program Management § 95.22 Payment. (a) Payment methods shall minimize the time elapsing between the transfer of...

Holocene paleoseismicity, temporal clustering, and probabilities of future large (M > 7) earthquakes on the Wasatch fault zone, Utah

USGS Publications Warehouse

McCalpin, J.P.; Nishenko, S.P.

1996-01-01

The chronology of M>7 paleoearthquakes on the central five segments of the Wasatch fault zone (WFZ) is one of the best dated in the world and contains 16 earthquakes in the past 5600 years with an average repeat time of 350 years. Repeat times for individual segments vary by a factor of 2, and range from about 1200 to 2600 years. Four of the central five segments ruptured between ??? 620??30 and 1230??60 calendar years B.P. The remaining segment (Brigham City segment) has not ruptured in the past 2120??100 years. Comparison of the WFZ space-time diagram of paleoearthquakes with synthetic paleoseismic histories indicates that the observed temporal clusters and gaps have about an equal probability (depending on model assumptions) of reflecting random coincidence as opposed to intersegment contagion. Regional seismicity suggests that for exposure times of 50 and 100 years, the probability for an earthquake of M>7 anywhere within the Wasatch Front region, based on a Poisson model, is 0.16 and 0.30, respectively. A fault-specific WFZ model predicts 50 and 100 year probabilities for a M>7 earthquake on the WFZ itself, based on a Poisson model, as 0.13 and 0.25, respectively. In contrast, segment-specific earthquake probabilities that assume quasi-periodic recurrence behavior on the Weber, Provo, and Nephi segments are less (0.01-0.07 in 100 years) than the regional or fault-specific estimates (0.25-0.30 in 100 years), due to the short elapsed times compared to average recurrence intervals on those segments. The Brigham City and Salt Lake City segments, however, have time-dependent probabilities that approach or exceed the regional and fault specific probabilities. For the Salt Lake City segment, these elevated probabilities are due to the elapsed time being approximately equal to the average late Holocene recurrence time. For the Brigham City segment, the elapsed time is significantly longer than the segment-specific late Holocene recurrence time.

Timeliness of Nongovernmental versus Governmental Global Outbreak Communications

PubMed Central

Mondor, Luke; Brownstein, John S.; Chan, Emily; Madoff, Lawrence C.; Pollack, Marjorie P.; Buckeridge, David L.

2012-01-01

To compare the timeliness of nongovernmental and governmental communications of infectious disease outbreaks and evaluate trends for each over time, we investigated the time elapsed from the beginning of an outbreak to public reporting of the event. We found that governmental sources improved the timeliness of public reporting of infectious disease outbreaks during the study period. PMID:22709741

Optimal Xylocoris flavipes (Reuter) (Hemiptera: Anthocoridae) density and time of introduction for suppression of bruchid progeny in stored legumes

Treesearch

Sharlene E. Sing; Richard T. Arbogast

2008-01-01

The influences of both predator density and elapsed time between initial infestation and introduction of predators were determined for suppression of bruchids infesting stored grain legumes by Xylocoris flavipes (Reuter) (Hemiptera: Anthocoridae). Predator density treatments consisted of zero, one, two, three, or five male:female pairs of adult

Hurricane Gladys, Gulf of Mexico as seen from the Apollo 7 spacecraft

NASA Technical Reports Server (NTRS)

1968-01-01

Hurricane Gladys, Gulf of Mexico, as seen from the Apollo 7 spacecraft during its 91st revolution of the earth. Photographed from an altitude of 99 nautical miles, at ground elapsed time of 144 hours and 27 minutes.

40 CFR 30.22 - Payment.

Code of Federal Regulations, 2014 CFR

2014-07-01

... remitted annually to Department of Health and Human Services, Payment Management System, P.O. Box 6021... NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 30.22 Payment. (a... time elapsing between the transfer of funds and disbursement by the recipient; and financial management...

40 CFR 30.22 - Payment.

Code of Federal Regulations, 2012 CFR

2012-07-01

... remitted annually to Department of Health and Human Services, Payment Management System, P.O. Box 6021... NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 30.22 Payment. (a... time elapsing between the transfer of funds and disbursement by the recipient; and financial management...

Method and apparatus for monitoring the thickness of a coal rib during rib formation

DOEpatents

Mowrey, Gary L.; Ganoe, Carl W.; Monaghan, William D.

1996-01-01

Apparatus for monitoring the position of a mining machine cutting a new entry in a coal seam relative to an adjacent, previously cut entry to determine the distance between a near face of the adjacent previously cut entry and a new face adjacent thereto of a new entry being cut by the mining machine which together define the thickness of a coal rib being formed between the new entry and the adjacent previously cut entry during the new entry-cutting operation. The monitoring apparatus; includes a transmit antenna mounted on the mining machine and spaced inwardly from the new face of the coal rib for transmitting radio energy towards the coal rib so that one portion of the radio energy is reflected by the new face which is defined at an air-coal interface between the new entry and the coal rib and another portion of the radio energy is reflected by the near face of the coal rib which is defined at an air-coal interface between the coal rib and the adjacent previously cut entry. A receive antenna mounted on the mining machine and spaced inwardly of the new face of the coal rib receives the one portion of the radio energy reflected by the new face and also receives the another portion of the radio energy reflected by the near face. A processor determines a first elapsed time period equal to the time required for the one portion of the radio energy reflected by the new face to travel between the transmit antenna and the receive antenna and also determines a second elapsed time period equal to the time required for the another portion of the radio energy reflected by the near face to travel between the transmit antenna and the receive antenna and thereafter calculates the thickness of the coal rib being formed as a function of the difference between the first and second elapsed time periods.

Emergent risk factors associated with eyeball loss and ambulatory vision loss after globe injuries.

PubMed

Hyun Lee, Seung; Ahn, Jae Kyoun

2010-07-01

The objective of this study was to evaluate risk factors associated with eyeball loss and ambulatory vision loss on emergent examination of patients with ocular trauma. We reviewed the medical records of 1,875 patients hospitalized in a single tertiary referral center between January 2003 and December 2007. Emergent examinations included a history of trauma, elapsed time between injury and hospital arrival, visible intraocular tissues, and initial visual acuity (VA) using a penlight. The main outcome measures were ocular survival and ambulatory vision survival (>20/200) at 1 year after trauma using univariate and multivariate regression analysis. The ocular trauma scores were significantly higher in open globe injuries than in closed globe injuries (p < 0.01). In open globe injuries, initial VA less than light perception (LP) and a history of golf ball injury were the significant risk factors associated with eyeball loss. Elapsed time more than 12 hours and visible intraocular tissues were the significant risk factors associated with ambulatory vision loss. The most powerful predictor of eyeball loss and ambulatory vision loss was eyeball rupture. In closed globe injuries, there were no significant risk factors of eyeball loss, whereas initial vision less than LP and the presence of relative afferent pupillary defect were the significant risk factors associated with ambulatory vision loss. An initial VA less than LP using a penlight, a history of golf ball injury, and elapsed time more than 12 hours between ocular trauma and hospital arrival were associated with eyeball loss and ambulatory vision loss. Physicians should bear these factors in mind so that they can more effectively counsel patients with such injuries.

Start-On-The-Part Transient Model for In-Situ Automated Tape Placement of Thermoplastic Composites

NASA Technical Reports Server (NTRS)

Costen, Robert c.; Marchello, Joseph M.

1997-01-01

Fabrication of a complex part by automated tape placement (ATP) can require starting up a new tape-end in the part interior, termed start-on-the-part. Careful thermal management of the starting transient is needed to achieve uniform crystallinity and inter-laminar weld strength - which is the objective of this modeling effort. The transient is modeled by a Fourier-Laplace transform solution of the time-dependent thermal transport equation in two spatial dimensions. The solution is subject to a quasi-steady approximation for the speed and length of the consolidation head. Sample calculations are done for the Langley ATP robot applying PEEK/carbon fiber composite and for two upgrades in robot performance. The head starts out almost at rest which meets an engineering requirement for accurate placement of the new tape-end. The head then rapidly accelerates until it reaches its steady state speed. This rapid acceleration, however, violates the quasi-steady approximation, so uniform weld strength and crystallinity during the starting transient are not actually achieved. The solution does give the elapsed time and distance from start-up to validity of the quasi-steady approximation - which quantifies the length of the non-uniform region. The elapsed time was always less than 0.1 s and the elapsed distance less than 1 cm. This quantification would allow the non-uniform region to be either trimmed away or compensated for in the design of a part. Such compensation would require experiments to measure the degree of non-uniformity, because the solution does not provide this information. The rapid acceleration suggests that the consolidation roller or belt be actively synchronized to avoid abrading the tape.

A Parallel Particle Swarm Optimization Algorithm Accelerated by Asynchronous Evaluations

NASA Technical Reports Server (NTRS)

Venter, Gerhard; Sobieszczanski-Sobieski, Jaroslaw

2005-01-01

A parallel Particle Swarm Optimization (PSO) algorithm is presented. Particle swarm optimization is a fairly recent addition to the family of non-gradient based, probabilistic search algorithms that is based on a simplified social model and is closely tied to swarming theory. Although PSO algorithms present several attractive properties to the designer, they are plagued by high computational cost as measured by elapsed time. One approach to reduce the elapsed time is to make use of coarse-grained parallelization to evaluate the design points. Previous parallel PSO algorithms were mostly implemented in a synchronous manner, where all design points within a design iteration are evaluated before the next iteration is started. This approach leads to poor parallel speedup in cases where a heterogeneous parallel environment is used and/or where the analysis time depends on the design point being analyzed. This paper introduces an asynchronous parallel PSO algorithm that greatly improves the parallel e ciency. The asynchronous algorithm is benchmarked on a cluster assembled of Apple Macintosh G5 desktop computers, using the multi-disciplinary optimization of a typical transport aircraft wing as an example.

Hyperkalemia after irradiation of packed red blood cells: Possible effects with intravascular fetal transfusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thorp, J.A.; Plapp, F.V.; Cohen, G.R.

1990-08-01

Plasma potassium, calcium, and albumin concentrations in irradiated blood, and in fetal blood before and after transfusion, were measured. Dangerously high plasma potassium levels were observed in some units of irradiated packed red blood cells (range, 13.9 to 66.5 mEq/L; mean, 44.7 mEq/L) and could be one possible explanation for the high incidence of fetal arrhythmia associated with fetal intravascular transfusion. There are many factors operative in the preparation of irradiated packed red blood cells that may predispose to high potassium levels: the age of the red blood cells, the number of procedures used to concentrate the blood, the durationmore » of time elapsed from concentration, the duration of time elapsed from irradiation, and the hematocrit. Use of fresh blood, avoidance of multiple packing procedures, limiting the hematocrit in the donor unit to less than or equal to 80%, and minimizing the time between concentration, irradiation and transfusion may minimize the potassium levels, and therefore making an additional washing procedure unnecessary.« less

49 CFR 239.105 - Debriefing and critique.

Code of Federal Regulations, 2013 CFR

2013-10-01

... emergency situation or full-scale simulation to determine the effectiveness of its emergency preparedness... passenger train emergency situation or full-scale simulation. (b) Exceptions. (1) No debriefing and critique...; (2) How much time elapsed between the occurrence of the emergency situation or full-scale simulation...

49 CFR 239.105 - Debriefing and critique.

Code of Federal Regulations, 2011 CFR

2011-10-01

... emergency situation or full-scale simulation to determine the effectiveness of its emergency preparedness... passenger train emergency situation or full-scale simulation. (b) Exceptions. (1) No debriefing and critique...; (2) How much time elapsed between the occurrence of the emergency situation or full-scale simulation...

49 CFR 239.105 - Debriefing and critique.

Code of Federal Regulations, 2010 CFR

2010-10-01

... emergency situation or full-scale simulation to determine the effectiveness of its emergency preparedness... passenger train emergency situation or full-scale simulation. (b) Exceptions. (1) No debriefing and critique...; (2) How much time elapsed between the occurrence of the emergency situation or full-scale simulation...

49 CFR 239.105 - Debriefing and critique.

Code of Federal Regulations, 2012 CFR

2012-10-01

... emergency situation or full-scale simulation to determine the effectiveness of its emergency preparedness... passenger train emergency situation or full-scale simulation. (b) Exceptions. (1) No debriefing and critique...; (2) How much time elapsed between the occurrence of the emergency situation or full-scale simulation...

Method To Display Data On A Face Mask

NASA Technical Reports Server (NTRS)

Moore, Kevin-Duron

1995-01-01

Proposed electronic instrument displays information on diver's or firefighter's face mask. Includes mask, prism, electronic readouts, transceiver and control electronics. Mounted at periphery of diver's field of view to provide data on elapsed time, depth, pressure, and temperature. Provides greater safety and convenience to user.

38 CFR 49.22 - Payment.

Code of Federal Regulations, 2011 CFR

2011-07-01

... NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 49.22 Payment. (a... elapsing between the transfer of funds and disbursement by the recipient, and financial management systems... a recipient organization shall be limited to the minimum amounts needed and be timed to be in...

34 CFR 74.22 - Payment.

Code of Federal Regulations, 2013 CFR

2013-07-01

... recipient; and (ii) Financial management systems that meet the standards for fund control and accountability... Human Services, Payment Management System, Rockville, MD 20852. Interest amounts up to $250 per year may... Management § 74.22 Payment. (a) Payment methods shall minimize the time elapsing between the transfer of...

34 CFR 74.22 - Payment.

Code of Federal Regulations, 2014 CFR

2014-07-01

... recipient; and (ii) Financial management systems that meet the standards for fund control and accountability... Human Services, Payment Management System, Rockville, MD 20852. Interest amounts up to $250 per year may... Management § 74.22 Payment. (a) Payment methods shall minimize the time elapsing between the transfer of...

13 CFR 143.20 - Standards for financial management systems.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Requirements Financial Administration § 143.20 Standards for financial management systems. (a) A State must... prohibitions of applicable statutes. (b) The financial management systems of other grantees and subgrantees... subgrant award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the...

15 CFR 24.20 - Standards for financial management systems.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Requirements Financial Administration § 24.20 Standards for financial management systems. (a) A State must... prohibitions of applicable statutes. (b) The financial management systems of other grantees and subgrantees... subgrant award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the...

13 CFR 143.20 - Standards for financial management systems.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Requirements Financial Administration § 143.20 Standards for financial management systems. (a) A State must... prohibitions of applicable statutes. (b) The financial management systems of other grantees and subgrantees... subgrant award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the...

13 CFR 143.20 - Standards for financial management systems.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Requirements Financial Administration § 143.20 Standards for financial management systems. (a) A State must... prohibitions of applicable statutes. (b) The financial management systems of other grantees and subgrantees... subgrant award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the...

15 CFR 24.20 - Standards for financial management systems.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Requirements Financial Administration § 24.20 Standards for financial management systems. (a) A State must... prohibitions of applicable statutes. (b) The financial management systems of other grantees and subgrantees... subgrant award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the...

13 CFR 143.20 - Standards for financial management systems.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Requirements Financial Administration § 143.20 Standards for financial management systems. (a) A State must... prohibitions of applicable statutes. (b) The financial management systems of other grantees and subgrantees... subgrant award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the...

28 CFR 66.20 - Standards for financial management systems.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Requirements Financial Administration § 66.20 Standards for financial management systems. (a) A State must... prohibitions of applicable statutes. (b) The financial management systems of other grantees and subgrantees... subgrant award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the...

Dating previously balanced rocks in seismically active parts of California and Nevada

USGS Publications Warehouse

Bell, J.W.; Brune, J.N.; Liu, T.; Zreda, M.; Yount, J.C.

1998-01-01

Precariously balanced boulders that could be knocked down by strong earthquake ground motion are found in some seismically active areas of southern California and Nevada. In this study we used two independent surface-exposure dating techniques - rock-varnish microlamination and cosmogenic 36Cl dating methodologies - to estimate minimum- and maximum-limiting ages, respectively, of the precarious boulders and by inference the elapsed time since the sites were shaken down. The results of the exposure dating indicate that all of the precarious rocks are >10.5 ka and that some may be significantly older. At Victorville and Jacumba, California, these results show that the precarious rocks have not been knocked down for at least 10.5 k.y., a conclusion in apparent conflict with some commonly used probabilistic seismic hazard maps. At Yucca Mountain, Nevada, the ages of the precarious rocks are >10.5 to >27.0 ka, providing an independent measure of the minimum time elapsed since faulting occurred on the Solitario Canyon fault.

Stochastic model of temporal changes of wind spectra in the free atmosphere

NASA Technical Reports Server (NTRS)

Huang, Y. H.

1974-01-01

Data for wind profile spectra changes with respect to time from Cape Kennedy, Florida for the time period from 28 November 1964 to 11 May 1967 have been analyzed. A universal statistical distribution of the spectral change which encompasses all vertical wave numbers, wind speed categories, and elapsed time has been developed for the standard deviation of the time changes of detailed wind profile spectra as a function of wave number.

The Impact of Wireless Technology Feedback on Inventory Management at a Dairy Manufacturing Plant

ERIC Educational Resources Information Center

Goomas, David T.

2012-01-01

Replacing the method of counting inventory from paper count sheets to that of wireless reliably reduced the elapsed time to complete a daily inventory of the storage cooler in a dairy manufacturing plant. The handheld computers delivered immediate prompts as well as auditory and visual feedback. Reducing the time to complete the daily inventory…

Cell assembly sequences arising from spike threshold adaptation keep track of time in the hippocampus

PubMed Central

Itskov, Vladimir; Curto, Carina; Pastalkova, Eva; Buzsáki, György

2011-01-01

Hippocampal neurons can display reliable and long-lasting sequences of transient firing patterns, even in the absence of changing external stimuli. We suggest that time-keeping is an important function of these sequences, and propose a network mechanism for their generation. We show that sequences of neuronal assemblies recorded from rat hippocampal CA1 pyramidal cells can reliably predict elapsed time (15-20 sec) during wheel running with a precision of 0.5sec. In addition, we demonstrate the generation of multiple reliable, long-lasting sequences in a recurrent network model. These sequences are generated in the presence of noisy, unstructured inputs to the network, mimicking stationary sensory input. Identical initial conditions generate similar sequences, whereas different initial conditions give rise to distinct sequences. The key ingredients responsible for sequence generation in the model are threshold-adaptation and a Mexican-hat-like pattern of connectivity among pyramidal cells. This pattern may arise from recurrent systems such as the hippocampal CA3 region or the entorhinal cortex. We hypothesize that mechanisms that evolved for spatial navigation also support tracking of elapsed time in behaviorally relevant contexts. PMID:21414904

Differential Encoding of Time by Prefrontal and Striatal Network Dynamics.

PubMed

Bakhurin, Konstantin I; Goudar, Vishwa; Shobe, Justin L; Claar, Leslie D; Buonomano, Dean V; Masmanidis, Sotiris C

2017-01-25

Telling time is fundamental to many forms of learning and behavior, including the anticipation of rewarding events. Although the neural mechanisms underlying timing remain unknown, computational models have proposed that the brain represents time in the dynamics of neural networks. Consistent with this hypothesis, changing patterns of neural activity dynamically in a number of brain areas-including the striatum and cortex-has been shown to encode elapsed time. To date, however, no studies have explicitly quantified and contrasted how well different areas encode time by recording large numbers of units simultaneously from more than one area. Here, we performed large-scale extracellular recordings in the striatum and orbitofrontal cortex of mice that learned the temporal relationship between a stimulus and a reward and reported their response with anticipatory licking. We used a machine-learning algorithm to quantify how well populations of neurons encoded elapsed time from stimulus onset. Both the striatal and cortical networks encoded time, but the striatal network outperformed the orbitofrontal cortex, a finding replicated both in simultaneously and nonsimultaneously recorded corticostriatal datasets. The striatal network was also more reliable in predicting when the animals would lick up to ∼1 s before the actual lick occurred. Our results are consistent with the hypothesis that temporal information is encoded in a widely distributed manner throughout multiple brain areas, but that the striatum may have a privileged role in timing because it has a more accurate "clock" as it integrates information across multiple cortical areas. The neural representation of time is thought to be distributed across multiple functionally specialized brain structures, including the striatum and cortex. However, until now, the neural code for time has not been compared quantitatively between these areas. Here, we performed large-scale recordings in the striatum and orbitofrontal cortex of mice trained on a stimulus-reward association task involving a delay period and used a machine-learning algorithm to quantify how well populations of simultaneously recorded neurons encoded elapsed time from stimulus onset. We found that, although both areas encoded time, the striatum consistently outperformed the orbitofrontal cortex. These results suggest that the striatum may refine the code for time by integrating information from multiple inputs. Copyright © 2017 the authors 0270-6474/17/370854-17$15.00/0.

Health-related quality of life in women with breast cancer in Korea: do sociodemographic characteristics and time since diagnosis make a difference?

PubMed

Chae, Young Ran; Seo, Kumin

2010-07-01

To describe whether levels of health-related quality of life (HRQOL) differ by sociodemographic characteristics and time since breast cancer diagnosis in women in Korea. A descriptive, cross-sectional study of women with breast cancer. An outpatient clinic of one large hospital in Seoul, Republic of Korea. A convenience sample of 244 women with breast cancer after mastectomy. Study participants completed sociodemographic characteristics and HRQOL questionnaires. Medical charts were reviewed to determine time since breast cancer diagnosis. Sociodemographic characteristics (age, marital status, employment status, education, monthly household income, and religion), time since diagnosis, and HRQOL. The psychological well-being domain scored the lowest among domains of HRQOL. Women who are younger, married, unemployed, highly educated, or religious, with higher monthly household income or with greater than one year elapsed time since diagnosis, had higher HRQOL. Study findings will be useful to establish priorities in planning nursing interventions to enhance HRQOL in care of women with breast cancer. Nursing interventions can be provided to Korean women with breast cancer who are not religious, who are older, single or widowed, or employed, with lower education level, with lower monthly household income, or with one year or less elapsed time since breast cancer diagnosis.

Automated Estimation of the Orbital Parameters of Jupiter's Moons

NASA Astrophysics Data System (ADS)

Western, Emma; Ruch, Gerald T.

2016-01-01

Every semester the Physics Department at the University of St. Thomas has the Physics 104 class complete a Jupiter lab. This involves taking around twenty images of Jupiter and its moons with the telescope at the University of St. Thomas Observatory over the course of a few nights. The students then take each image and find the distance from each moon to Jupiter and plot the distances versus the elapsed time for the corresponding image. Students use the plot to fit four sinusoidal curves of the moons of Jupiter. I created a script that automates this process for the professor. It takes the list of images and creates a region file used by the students to measure the distance from the moons to Jupiter, a png image that is the graph of all the data points and the fitted curves of the four moons, and a csv file that contains the list of images, the date and time each image was taken, the elapsed time since the first image, and the distances to Jupiter for Io, Europa, Ganymede, and Callisto. This is important because it lets the professor spend more time working with the students and answering questions as opposed to spending time fitting the curves of the moons on the graph, which can be time consuming.

Parents and teachers reporting on a child's emotional and behavioural problems following severe traumatic brain injury (TBI): the moderating effect of time.

PubMed

Silberg, Tamar; Tal-Jacobi, Dana; Levav, Miriam; Brezner, Amichai; Rassovsky, Yuri

2015-01-01

Gathering information from parents and teachers following paediatric traumatic brain injury (TBI) has substantial clinical value for diagnostic decisions. Yet, a multi-informant approach has rarely been addressed when evaluating children at the chronic stage post-injury. In the current study, the goals were to examine (1) differences between parents' and teachers' reports on a child's emotional and behavioural problems and (2) the effect of time elapsed since injury on each rater's report. A sample of 42 parents and 42 teachers of children following severe TBI completed two standard rating scales. Receiver Operating Characteristic (ROC) curves were used to determine whether time elapsed since injury reliably distinguished children falling above and below clinical levels. Emotional-behavioural scores of children following severe TBI fell within normal range, according to both teachers and parents. Significant differences were found between parents' reports relatively close to the time of injury and 2 years post-injury. However, no such differences were observed in teachers' ratings. Parents and teachers of children following severe TBI differ in their reports on a child's emotional and behavioural problems. The present study not only underscores the importance of multiple informants, but also highlights, for the first time, the possibility that informants' perceptions may vary across time.

Obama's Education Record

ERIC Educational Resources Information Center

Petrilli, Michael; Eberhardt, Tyson

2012-01-01

In the fourth and final year of the first term of the Obama administration, enough time has elapsed to provide an opportunity for at least an interim assessment. Senator Lamar Alexander has commented that he has "a lot of admiration" for Obama's education secretary, Arne Duncan, and "respect" for the president's "positions…

Twin Paradox: A Complete Treatment from the Point of View of Each Twin.

ERIC Educational Resources Information Center

Perrin, Robert

1979-01-01

Modifies and expands on the treatment of the twin paradox by solving the gravitational field equations and geodesic equations of motion in the traveling twin's reference frame, thus determining the time elapsed on the Earth during the periods of acceleration. (Author/GA)

28 CFR 66.20 - Standards for financial management systems.

Code of Federal Regulations, 2013 CFR

2013-07-01

... subgrant award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Standards for financial management... Requirements Financial Administration § 66.20 Standards for financial management systems. (a) A State must...

28 CFR 66.20 - Standards for financial management systems.

Code of Federal Regulations, 2014 CFR

2014-07-01

... subgrant award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Standards for financial management... Requirements Financial Administration § 66.20 Standards for financial management systems. (a) A State must...

28 CFR 66.20 - Standards for financial management systems.

Code of Federal Regulations, 2011 CFR

2011-07-01

... subgrant award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Standards for financial management... Requirements Financial Administration § 66.20 Standards for financial management systems. (a) A State must...

22 CFR 145.22 - Payment.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Payment. 145.22 Section 145.22 Foreign....22 Payment. (a) Payment methods shall minimize the time elapsing between the transfer of funds from... request for reimbursement at least monthly when electronic funds transfers are not used. (f) If a...

22 CFR 145.22 - Payment.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Payment. 145.22 Section 145.22 Foreign....22 Payment. (a) Payment methods shall minimize the time elapsing between the transfer of funds from... request for reimbursement at least monthly when electronic funds transfers are not used. (f) If a...

22 CFR 145.22 - Payment.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Payment. 145.22 Section 145.22 Foreign....22 Payment. (a) Payment methods shall minimize the time elapsing between the transfer of funds from... request for reimbursement at least monthly when electronic funds transfers are not used. (f) If a...

22 CFR 145.22 - Payment.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Payment. 145.22 Section 145.22 Foreign....22 Payment. (a) Payment methods shall minimize the time elapsing between the transfer of funds from... request for reimbursement at least monthly when electronic funds transfers are not used. (f) If a...

Northwestern Argentina as seen from the Apollo 7 spacecraft

NASA Technical Reports Server (NTRS)

1968-01-01

Puna de Atacama area of northwestern Argentina, Provinces of Salta and Catamarca, as seen from the Apollo 7 spacecraft during its 154th revolution of the earth. Photographed from an altitude of 175 nautical miles, at ground elapsed time of 243 hours and 58 minutes.

Problem Solvers: Solutions--Playing Basketball

ERIC Educational Resources Information Center

Smith, Jeffrey

2014-01-01

In this article, fourth grade Upper Allen Elementary School (Mechanicsburg, Pennsylvania) teacher Jeffrey Smith describes his exploration of the Playing Basketball activity. Herein he describes how he found the problem to be an effective way to review concepts associated with the measurement of elapsed time with his students. Additionally, it…

31 CFR 205.11 - What requirements apply to funding techniques?

Code of Federal Regulations, 2014 CFR

2014-07-01

... Program Agency must minimize the time elapsing between the transfer of funds from the United States Treasury and the State's payout of funds for Federal assistance program purposes, whether the transfer... EFFICIENT FEDERAL-STATE FUNDS TRANSFERS Rules Applicable to Federal Assistance Programs Included in a...

Simulation of in-hospital pediatric medical emergencies and cardiopulmonary arrests: highlighting the importance of the first 5 minutes.

PubMed

Hunt, Elizabeth A; Walker, Allen R; Shaffner, Donald H; Miller, Marlene R; Pronovost, Peter J

2008-01-01

Outcomes of in-hospital pediatric cardiopulmonary arrest are dismal. Recent data suggest that the quality of basic and advanced life support delivered to adults is low and contributes to poor outcomes, but few data regarding pediatric events have been reported. The objectives of this study were to (1) measure the median elapsed time to initiate important resuscitation maneuvers in simulated pediatric medical emergencies (ie, "mock codes") and (2) identify the types and frequency of errors committed during pediatric mock codes. A prospective, observational study was conducted of 34 consecutive hospital-based mock codes. A mannequin or computerized simulator was used to enact unannounced, simulated crisis situations involving children with respiratory distress or insufficiency, respiratory arrest, hemodynamic instability, and/or cardiopulmonary arrest. Assessment included time elapsed to initiation of specific resuscitation maneuvers and deviation from American Heart Association guidelines. Among the 34 mock codes, the median time to assessment of airway and breathing was 1.3 minutes, to administration of oxygen was 2.0 minutes, to assessment of circulation was 4.0 minutes, to arrival of any physician was 3.0 minutes, and to arrival of first member of code team was 6.0 minutes. Among cardiopulmonary arrest scenarios, elapsed time to initiation of compressions was 1.5 minutes and to request for defibrillator was 4.3 minutes. In 75% of mock codes, the team deviated from American Heart Association pediatric basic life support protocols, and in 100% of mock codes there was a communication error. Alarming delays and deviations occur in the major components of pediatric resuscitation. Future educational and organizational interventions should focus on improving the quality of care delivered during the first 5 minutes of resuscitation. Simulation of pediatric crises can identify targets for educational intervention to improve pediatric cardiopulmonary resuscitation and, ideally, outcomes.

Effects of Videogame Distraction using a Virtual Reality Type Head-Mounted Display Helmet on Cold Pressor Pain in Children

PubMed Central

Weiss, Karen E.; Dillinger Clendaniel, Lindsay; Law, Emily F.; Ackerman, Claire Sonntag; McKenna, Kristine D.

2009-01-01

Objective To test whether a head-mounted display helmet enhances the effectiveness of videogame distraction for children experiencing cold pressor pain. Method Forty-one children, aged 6–14 years, underwent one or two baseline cold pressor trials followed by two distraction trials in which they played the same videogame with and without the helmet in counterbalanced order. Pain threshold (elapsed time until the child reported pain) and pain tolerance (total time the child kept the hand submerged in the cold water) were measured for each cold pressor trial. Results Both distraction conditions resulted in improved pain tolerance relative to baseline. Older children appeared to experience additional benefits from using the helmet, whereas younger children benefited equally from both conditions. The findings suggest that virtual reality technology can enhance the effects of distraction for some children. Research is needed to identify the characteristics of children for whom this technology is best suited. PMID:18367495

Transfusion monitoring: care practice analysis in a public teaching hospital

PubMed Central

dos Reis, Valesca Nunes; Paixão, Isabella Bertolin; Perrone, Ana Carolina Amaral de São José; Monteiro, Maria Inês; dos Santos, Kelli Borges

2016-01-01

ABSTRACT Objective To analyze the process of recording transfusion monitoring at a public teaching hospital. Methods A descriptive and retrospective study with a quantitative approach, analyzing the instruments to record transfusion monitoring at a public hospital in a city in the State of Minas Gerais (MG). Data were collected on the correct completion of the instrument, time elapsed from transfusions, records of vital signs, type of blood component more frequently transfused, and hospital unit where transfusion was performed. Results A total of 1,012 records were analyzed, and 53.4% of them had errors in filling in the instruments, 6% of transfusions started after the recommended time, and 9.3% of patients had no vital signs registered. Conclusion Failures were identified in the process of recording transfusion monitoring, and they could result in more adverse events related to the administration of blood components. Planning and implementing strategies to enhance recording and to improve care delivered are challenging. PMID:27074233

LANL Robotic Vessel Scanning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Webber, Nels W.

Los Alamos National Laboratory in J-1 DARHT Operations Group uses 6ft spherical vessels to contain hazardous materials produced in a hydrodynamic experiment. These contaminated vessels must be analyzed by means of a worker entering the vessel to locate, measure, and document every penetration mark on the vessel. If the worker can be replaced by a highly automated robotic system with a high precision scanner, it will eliminate the risks to the worker and provide management with an accurate 3D model of the vessel presenting the existing damage with the flexibility to manipulate the model for better and more in-depth assessment.Themore » project was successful in meeting the primary goal of installing an automated system which scanned a 6ft vessel with an elapsed time of 45 minutes. This robotic system reduces the total time for the original scope of work by 75 minutes and results in excellent data accumulation and transmission to the 3D model imaging program.« less

Replantation surgery in Quebec: The bottlenecks to rapid care

PubMed Central

Borsuk, Daniel E; Zadeh, Teanoosh; Lee, Chen; Moore, Karl; Tan, Grace

2006-01-01

INTRODUCTION Time delays resulting in prolonged ischemia have a significant impact on the successful reattachment of amputated body parts. No studies have addressed the issues surrounding delays from the time of the accident to the start of replantation surgery. The present paper identifies the bottlenecks that prolong the time before patients are able to gain access to a replant team. METHODS A total of 50 patients underwent microsurgical replantation, because of traumatic amputation, at a university-based hospital from 1996 to 2003. The charts were analyzed to ascertain individual time intervals from the onset of injury until the beginning of replant surgery. RESULTS The average length of time for patients who came directly to the replant centre was 3 h 40 min before surgery began. In contrast, for those referred from outlying hospitals, the elapsed time was 6 h 21 min. CONCLUSIONS Two major bottlenecks were found. First, for patients who were referred from other health centres, delays were due to a lack of information as to where patients could receive appropriate replant surgery. Second, delays at the replant centre were primarily due to insufficient physical and human resources in the operating room. PMID:19554107

14 CFR 255.4 - Display of information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... with the requirements of this section. (1) Each system must offer an integrated display that uses the.... (2) Each integrated display offered by a system must either use elapsed time as a significant factor in selecting service options from the database or give single-plane flights a preference over...

46 CFR 131.610 - Logbooks and records.

Code of Federal Regulations, 2011 CFR

2011-10-01

... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Logs § 131... them. (d) When a voyage is completed, or after a specified time has elapsed, the master shall file the... alternative log or record for making entries required by law, including regulations in this subchapter. This...

46 CFR 131.610 - Logbooks and records.

Code of Federal Regulations, 2010 CFR

2010-10-01

... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Logs § 131... them. (d) When a voyage is completed, or after a specified time has elapsed, the master shall file the... alternative log or record for making entries required by law, including regulations in this subchapter. This...

5 CFR 180.108 - Settlement of claims.

Code of Federal Regulations, 2010 CFR

2010-01-01

... purchase or exchange. The amount payable will be determined by applying the principles of depreciation to the adjusted dollar value or other base price of property lost or damaged beyond economical repair; by... cost, condition when damaged beyond economical repair or lost, and the time elapsed between the date of...

32 CFR 32.21 - Standards for financial management systems.

Code of Federal Regulations, 2010 CFR

2010-07-01

.... For awards that support research, it should be noted that it is generally not appropriate to develop... that support research. (5) Written procedures to minimize the time elapsing between the transfer of... Cash Management Improvement Act (CMIA) (Pub. L. 101-453) govern, payment methods of State agencies...

29 CFR 1926.804 - Definitions applicable to this subpart.

Code of Federal Regulations, 2013 CFR

2013-07-01

... pressure, and a second exposure to compressed air does not occur until at least 12 consecutive hours of exposure to normal atmospheric pressure has elapsed since the employee has been under pressure. (k... decompression time exceeds 75 minutes. (q) Working chamber—The space or compartment under air pressure in which...

48 CFR 852.236-84 - Schedule of work progress.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Schedule of work progress... Schedule of work progress. As prescribed in 836.575, insert the following clause: Schedule of Work Progress... indicates the anticipated installation of work versus the elapsed contract time, for the approval of the...

Hurricane Gladys, Gulf of Mexico as seen from the Apollo 7 spacecraft

NASA Image and Video Library

1968-10-17

AS07-07-1877 (17 Oct. 1968) --- Hurricane Gladys, Gulf of Mexico, as seen from the Apollo 7 spacecraft during its 91st revolution of the earth. Photographed from an altitude of 99 nautical miles, at ground elapsed time of 144 hours and 27 minutes.

45 CFR 1183.20 - Standards for financial management systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the... 45 Public Welfare 3 2014-10-01 2014-10-01 false Standards for financial management systems. 1183... Financial Administration § 1183.20 Standards for financial management systems. (a) A State must expand and...

45 CFR 92.20 - Standards for financial management systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

... subgrant award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the... 45 Public Welfare 1 2013-10-01 2013-10-01 false Standards for financial management systems. 92.20...-Award Requirements Financial Administration § 92.20 Standards for financial management systems. (a) A...

34 CFR 80.20 - Standards for financial management systems.

Code of Federal Regulations, 2012 CFR

2012-07-01

... award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the... 34 Education 1 2012-07-01 2012-07-01 false Standards for financial management systems. 80.20... Financial Administration § 80.20 Standards for financial management systems. (a) A State must expand and...

45 CFR 1174.20 - Standards for financial management systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the... 45 Public Welfare 3 2014-10-01 2014-10-01 false Standards for financial management systems. 1174... Financial Administration § 1174.20 Standards for financial management systems. (a) A State must expand and...

45 CFR 92.20 - Standards for financial management systems.

Code of Federal Regulations, 2012 CFR

2012-10-01

... subgrant award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the... 45 Public Welfare 1 2012-10-01 2012-10-01 false Standards for financial management systems. 92.20...-Award Requirements Financial Administration § 92.20 Standards for financial management systems. (a) A...

45 CFR 602.20 - Standards for financial management systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... subgrant award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the... 45 Public Welfare 3 2014-10-01 2014-10-01 false Standards for financial management systems. 602.20... GOVERNMENTS Post-Award Requirements § 602.20 Standards for financial management systems. (a) A State must...

45 CFR 1174.20 - Standards for financial management systems.

Code of Federal Regulations, 2011 CFR

2011-10-01

... award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the... 45 Public Welfare 3 2011-10-01 2011-10-01 false Standards for financial management systems. 1174... Financial Administration § 1174.20 Standards for financial management systems. (a) A State must expand and...

34 CFR 80.20 - Standards for financial management systems.

Code of Federal Regulations, 2013 CFR

2013-07-01

... award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the... 34 Education 1 2013-07-01 2013-07-01 false Standards for financial management systems. 80.20... Financial Administration § 80.20 Standards for financial management systems. (a) A State must expand and...

45 CFR 1183.20 - Standards for financial management systems.

Code of Federal Regulations, 2011 CFR

2011-10-01

... award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the... 45 Public Welfare 3 2011-10-01 2011-10-01 false Standards for financial management systems. 1183... Financial Administration § 1183.20 Standards for financial management systems. (a) A State must expand and...

34 CFR 80.20 - Standards for financial management systems.

Code of Federal Regulations, 2011 CFR

2011-07-01

... award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the... 34 Education 1 2011-07-01 2011-07-01 false Standards for financial management systems. 80.20... Financial Administration § 80.20 Standards for financial management systems. (a) A State must expand and...

45 CFR 602.20 - Standards for financial management systems.

Code of Federal Regulations, 2012 CFR

2012-10-01

... subgrant award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the... 45 Public Welfare 3 2012-10-01 2012-10-01 false Standards for financial management systems. 602.20... GOVERNMENTS Post-Award Requirements § 602.20 Standards for financial management systems. (a) A State must...

10 CFR 600.220 - Standards for financial management systems.

Code of Federal Regulations, 2011 CFR

2011-01-01

... subgrant award documents, etc. (7) Cash management. Procedures for minimizing the time elapsing between the... 10 Energy 4 2011-01-01 2011-01-01 false Standards for financial management systems. 600.220... Post-Award Requirements § 600.220 Standards for financial management systems. (a) A State must expend...

Mission Control Center (MCC) - Apollo 15 Launch - MSC

NASA Image and Video Library

1971-07-26

S71-41357 (26 July 1971) --- An overall, wide-angle lens view of activity in the Mission Operations Control Room in the Mission Control Center minutes after the launch of the Apollo 15 lunar landing mission. Ground elapsed time was 45 minutes and 42 seconds when this photograph was taken.

Island of Oahu, State of Hawaii, as seen from the Apollo 7 spacecraft

NASA Technical Reports Server (NTRS)

1968-01-01

Island of Oahu, State of Hawaii, as seen from the Apollo 7 spacecraft during its 51st revolution of the earth. Photographed from an altitude of 122 nautical miles, at ground elapsed time of 81 hours. Diamond Head and Pearl Harbor are clearly visible.

54. DETAIL OF GENERAL ELECTRIC AIRBORNE BEACON EQUIPMENT TEST SET ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

54. DETAIL OF GENERAL ELECTRIC AIRBORNE BEACON EQUIPMENT TEST SET (LEFT) AND ASSOCIATED GOULD BRUSH CHART RECORDERS (RIGHT). ELAPSED TIME COUNTER SITS ATOP AIRBORNE BEACON EQUIPMENT TEST SET. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Operations Building, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

22 CFR 518.22 - Payment.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Payment. 518.22 Section 518.22 Foreign Relations... and Program Management § 518.22 Payment. (a) Payment methods shall minimize the time elapsing between... reimbursement at least monthly when electronic funds are not used. (f) If a recipient cannot meet the criteria...

Long-time predictions in nonlinear dynamics

NASA Technical Reports Server (NTRS)

Szebehely, V.

1980-01-01

It is known that nonintegrable dynamical systems do not allow precise predictions concerning their behavior for arbitrary long times. The available series solutions are not uniformly convergent according to Poincare's theorem and numerical integrations lose their meaningfulness after the elapse of arbitrary long times. Two approaches are the use of existing global integrals and statistical methods. This paper presents a generalized method along the first approach. As examples long-time predictions in the classical gravitational satellite and planetary problems are treated.

Time to Degree: A National View of the Time Enrolled and Elapsed for Associate and Bachelor's Degree Earners. (Signature Report No. 11)

ERIC Educational Resources Information Center

Shapiro, Doug; Dundar, Afet; Wakhungu, Phoebe Khasiala; Yuan, Xin; Nathan, Angel; Hwang, Youngsik

2016-01-01

This report examines time to degree completion for a cohort of students who earned an associate degree as their first and only postsecondary degree or a bachelor's degree as their first four-year degree between July 1, 2014, and June 30, 2015. Overall, the average time enrolled for associate and bachelor's degree earners was 3.3 years and 5.1…

Actual Operation Simulation of RESSOX Ground Experiments

DTIC Science & Technology

2010-11-01

Note 1289,” (Hewlett-Packard), 60 pp. [5] F. Tappero, A. Dempster, T . Iwata, M. Imae, T . Ikegami , Y. Fukuyama, K. Hagimoto, and A. Iwasaki, 2006...Delay Ionospheric Delay Ku-band Delay Estimation Frequency- Independent part Frequency- Dependent part Elapsed Time with Current Time Set as 0 (s) T ...im e t o b e A d ju s te d 0-6-105 Extrapolated with First- Order Least-Squares Filter Time Adjustment Command 42 nd Annual Precise Time and Time

Teaching binocular indirect ophthalmoscopy to novice residents using an augmented reality simulator.

PubMed

Rai, Amandeep S; Rai, Amrit S; Mavrikakis, Emmanouil; Lam, Wai Ching

2017-10-01

To compare the traditional teaching approach of binocular indirect ophthalmoscopy (BIO) to the EyeSI augmented reality (AR) BIO simulator. Prospective randomized control trial. 28 post-graduate year one (PGY1) ophthalmology residents. Residents were recruited at the 2012 Toronto Ophthalmology Residents Introductory Course (TORIC). 15 were randomized to conventional teaching (Group 1), and 13 to augmented reality simulator training (Group 2). 3 vitreoretinal fellows were enrolled to serve as experts. Evaluations were completed on the simulator, with 3 tasks, and outcome measures were total raw score, total time elapsed, and performance. Following conventional training, Group 1 residents were outperformed by vitreoretinal fellows with respect to all 3 outcome measures. Following AR training, Group 2 residents demonstrated superior total scores and performance compared to Group 1 residents. Once the Group 1 residents also completed the AR BIO training, there was a significant improvement compared to their baseline scores, and were now on par with Group 2 residents. This study provides construct validity for the EyeSI AR BIO simulator and demonstrates that it may be superior to conventional BIO teaching for novice ophthalmology residents. Copyright © 2017 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

Expertise on Cognitive Workloads and Performance During Navigation and Target Detection

DTIC Science & Technology

2012-03-01

requiring little or no attention 1. Little confusion, risk, frustration, or anxiety exists and can be easily accomodated 2. Occasionally have spare...to confusion, frustration, or anxiety noticeably adds to workload. Significant compensation is required to maintain adequate performance. 3... anxiety . High to extreme determination and self- control required 59 Field Description elapsedTime (sec) Continuous measurement of time from the

Stratification of Time to First Citation for Articles Published in the "Journal of Research in Music Education": A Bibliometric Analysis

ERIC Educational Resources Information Center

Hancock, Carl B.

2015-01-01

The author examined the speed of research dissemination by determining the time elapsed from publication to first citation for 617 articles in the "Journal of Research in Music Education (JRME)". Google Scholar was used to create a unique data set of 6,930 references originating from journals in the arts, education, music, and other…

Development of Vector Parabolic Equation Technique for Propagation in Urban and Tunnel Environments

DTIC Science & Technology

2010-09-01

relativistic quantum mechanics J. Phys. A: Math. Gen. 16 1869–84 [8] Nottale L 1995 Scale relativity, fractal space- time and quantum mechanics Quantum...proportional to the “ time ” elapsed. By performing various approximations to the transfer function, several approximate absorbing boundary condi- tions...The public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing

[Ante-natal corticosteroids and prevention of respiratory distress in the premature newborn: usefulness of rescue treatment].

PubMed

López-Suárez, O; García-Magán, C; Saborido-Fiaño, R; Pérez-Muñuzuri, A; Baña-Souto, A; Couce-Pico, M L

2014-08-01

The effectiveness of antenatal corticosteroid therapy for foetal lung maturation in pre-term infants is well known, but there is uncertainty about the time that the treatment remains effective. A descriptive, longitudinal study was conducted to determine whether the need for surfactant administration was determined by the time-lapse between corticosteroids administration and delivery, and when repeating the doses of maternal corticosteroids should be considered. A total of 91 premature infants ≤32 weeks and/or ≤1,500 g (limit 34+6 weeks) whose mothers had received a complete course of corticosteroids were included. In patients at 27-34+6 weeks, we found that the longer the time elapsed between delivery and administration of corticosteroids, most likely were the babies to require treatment with surfactant (P=.027). The resulting ROC curve determined an 8-days cut-off after which repeating a dose of corticosteroids should be assessed. Copyright © 2013 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

Time-lapse microscopy using smartphone with augmented reality markers.

PubMed

Baek, Dongyoub; Cho, Sungmin; Yun, Kyungwon; Youn, Keehong; Bang, Hyunwoo

2014-04-01

A prototype system that replaces the conventional time-lapse imaging in microscopic inspection for use with smartphones is presented. Existing time-lapse imaging requires a video data feed between a microscope and a computer that varies depending on the type of image grabber. Even with proper hardware setups, a series of tedious and repetitive tasks is still required to relocate to the region-of-interest (ROI) of the specimens. In order to simplify the system and improve the efficiency of time-lapse imaging tasks, a smartphone-based platform utilizing microscopic augmented reality (μ-AR) markers is proposed. To evaluate the feasibility and efficiency of the proposed system, a user test was designed and performed, measuring the elapse time for a trial of the task starting from the execution of the application software to the completion of restoring and imaging of an ROI saved in advance. The results of the user test showed that the average elapse time was 65.3 ± 15.2 s with 6.86 ± 3.61 μm of position error and 0.08 ± 0.40 degrees of angle error. This indicates that the time-lapse imaging task was accomplished rapidly with a high level of accuracy. Thus, simplification of both the system and the task was achieved via our proposed system. Copyright © 2014 Wiley Periodicals, Inc.

Environmentally transmitted parasites: Host-jumping in a heterogeneous environment.

PubMed

Caraco, Thomas; Cizauskas, Carrie A; Wang, Ing-Nang

2016-05-21

Groups of chronically infected reservoir-hosts contaminate resource patches by shedding a parasite׳s free-living stage. Novel-host groups visit the same patches, where they are exposed to infection. We treat arrival at patches, levels of parasite deposition, and infection of the novel host as stochastic processes, and derive the expected time elapsing until a host-jump (initial infection of a novel host) occurs. At stationarity, mean parasite densities are independent of reservoir-host group size. But within-patch parasite-density variances increase with reservoir group size. The probability of infecting a novel host declines with parasite-density variance; consequently larger reservoir groups extend the mean waiting time for host-jumping. Larger novel-host groups increase the probability of a host-jump during any single patch visit, but also reduce the total number of visits per unit time. Interaction of these effects implies that the waiting time for the first infection increases with the novel-host group size. If the reservoir-host uses resource patches in any non-uniform manner, reduced spatial overlap between host species increases the waiting time for host-jumping. Copyright © 2016 Elsevier Ltd. All rights reserved.

Nonparametric change point estimation for survival distributions with a partially constant hazard rate.

PubMed

Brazzale, Alessandra R; Küchenhoff, Helmut; Krügel, Stefanie; Schiergens, Tobias S; Trentzsch, Heiko; Hartl, Wolfgang

2018-04-05

We present a new method for estimating a change point in the hazard function of a survival distribution assuming a constant hazard rate after the change point and a decreasing hazard rate before the change point. Our method is based on fitting a stump regression to p values for testing hazard rates in small time intervals. We present three real data examples describing survival patterns of severely ill patients, whose excess mortality rates are known to persist far beyond hospital discharge. For designing survival studies in these patients and for the definition of hospital performance metrics (e.g. mortality), it is essential to define adequate and objective end points. The reliable estimation of a change point will help researchers to identify such end points. By precisely knowing this change point, clinicians can distinguish between the acute phase with high hazard (time elapsed after admission and before the change point was reached), and the chronic phase (time elapsed after the change point) in which hazard is fairly constant. We show in an extensive simulation study that maximum likelihood estimation is not robust in this setting, and we evaluate our new estimation strategy including bootstrap confidence intervals and finite sample bias correction.

Cone-beam computed tomography fusion and navigation for real-time positron emission tomography-guided biopsies and ablations: a feasibility study.

PubMed

Abi-Jaoudeh, Nadine; Mielekamp, Peter; Noordhoek, Niels; Venkatesan, Aradhana M; Millo, Corina; Radaelli, Alessandro; Carelsen, Bart; Wood, Bradford J

2012-06-01

To describe a novel technique for multimodality positron emission tomography (PET) fusion-guided interventions that combines cone-beam computed tomography (CT) with PET/CT before the procedure. Subjects were selected among patients scheduled for a biopsy or ablation procedure. The lesions were not visible with conventional imaging methods or did not have uniform uptake on PET. Clinical success was defined by adequate histopathologic specimens for molecular profiling or diagnosis and by lack of enhancement on follow-up imaging for ablation procedures. Time to target (time elapsed between the completion of the initial cone-beam CT scan and first tissue sample or treatment), total procedure time (time from the moment the patient was on the table until the patient was off the table), and number of times the needle was repositioned were recorded. Seven patients underwent eight procedures (two ablations and six biopsies). Registration and procedures were completed successfully in all cases. Clinical success was achieved in all biopsy procedures and in one of the two ablation procedures. The needle was repositioned once in one biopsy procedure only. On average, the time to target was 38 minutes (range 13-54 min). Total procedure time was 95 minutes (range 51-240 min, which includes composite ablation). On average, fluoroscopy time was 2.5 minutes (range 1.3-6.2 min). An integrated cone-beam CT software platform can enable PET-guided biopsies and ablation procedures without the need for additional specialized hardware. Copyright © 2012 SIR. Published by Elsevier Inc. All rights reserved.

Increasing cardiopulmonary aerobic activity improves motor cognitive response time: An inference from preliminary one-group pretest-posttest quasi-experimental study.

PubMed

Mishra, Rajnee; Dasgupta, Aurodeep; Mohan, Vivek; Aranha, Vencita Priyanka; Samuel, Asir John

Motor cognitive response time (MCRT) is the time elapsed between presenting a stimulus and the time taken by that individual to respond to that stimulus through a motor performance. After completing aerobic exercise, there are various changes that takes place, one of which might be change in cognitive function. Whether cardiopulmonary aerobic activity/capacity has an impact on MCRT is not explored yet. Copyright © 2017. Published by Elsevier B.V.

Novel color additive for chlorine disinfectants corrects deficiencies in spray surface coverage and wet-contact time and checks for correct chlorine concentration.

PubMed

Tyan, Kevin; Jin, Katherine; Kang, Jason; Kyle, Aaron M

2018-04-18

Bleach sprays suffer from poor surface coverage, dry out before reaching proper contact time, and can be inadvertently over-diluted to ineffective concentrations. Highlight ® , a novel color additive for bleach that fades to indicate elapsed contact time, maintained >99.9% surface coverage over full contact time and checked for correct chlorine concentration. Copyright © 2018 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

On Vastness and Variability: Cultural Transmission, Historicity, and the Paleoindian Record in Eastern South America.

PubMed

Araujo, Astolfo G M

2015-01-01

Eastern South America, or what is today Brazilian territory, poses interesting questions about the early human occupation of the Americas. Three totally distinct and contemporaneous lithic technologies, dated between 11,000 and 10,000 14C BP, are present in different portions of the country: the Umbu tradition in the south, with its formal bifacial industry, with well-retouched scrapers and bifacial points; the Itaparica tradition in the central-west / northwest, totally unifacial, whose only formal artifacts are limaces; and the "Lagoa Santa" industry, completely lacking any formal artifacts, composed mainly of small quartz flakes. Our data suggests that these differences are not related to subsistence or raw-material constraints, but rather to different cultural norms and transmission of strongly divergent chaînes opératoires. Such diversity in material culture, when viewed from a cultural transmission (CT) theory standpoint, seems at odds with a simple Clovis model as the origin of these three cultural traditions given the time elapsed since the first Clovis ages and the expected population structure of the early South American settlers.

Island of Oahu, State of Hawaii, as seen from the Apollo 7 spacecraft

NASA Image and Video Library

1968-10-14

AS7-07-1741 (14 Oct. 1968) --- Island of Oahu, State of Hawaii, as seen from the Apollo 7 spacecraft during its 51st revolution of Earth. Photographed from an altitude of 122 nautical miles, at ground elapsed time of 81 hours. Diamond Head and Pearl Harbor are clearly visible.

75 FR 76054 - Detroit Edison Company Fermi, Unit 2; Exemption

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-07

... licensee anticipates using rail to ship radioactive waste. From the licensee's experience with radioactive..., section III.E, to investigate and file a report to the NRC if shipments of low-level radioactive waste are... exemption would extend the time period that can elapse during shipments of low-level radioactive waste...

Military Potential Test of Elapsed-Time Indicator, P/N 85986X

DTIC Science & Technology

1967-06-13

consisting basically of an electrolytic mercury cell, an accutron-quality mercury battery, and a pressure switch . The unit weighs 1. 687 ounces. Installed, it...orientation from 18 inches’ distance. The test item is actuated by a pressure switch which senses an actuating pressure of 40 t 5 pounds per square inch

Persian Gulf are of Iran, Qeshm Island, as seen from the Apollo 7 spacecraft

NASA Image and Video Library

1968-10-12

AS7-05-1615 (12 Oct. 1968) --- Persian Gulf coastal area of Iran, Qeshm Island, as seen from the Apollo 7 spacecraft during its 24th revolution of Earth. Photographed from an altitude of approximately 130 nautical miles, at ground elapsed time of 37 hours and 23 minutes.

Suez Canal, Gulf of Suez, Sinai Peninsula, Egypt, as seen from the Apollo 7

NASA Image and Video Library

1968-10-12

Suez Canal, Gulf of Suez, Sinai Peninsula, United Arab Republic (Egypt), Mediterranean Sea, as seen from the Apollo 7 spacecraft during its 13th revolution of the earth. Photographed from an altitude of 126 nautical miles, at ground elapsed time of 19 hours and 42 minutes.

A Longitudinal Analysis of PTSD Symptom Course: Delayed-Onset PTSD in Somalia Peacekeepers

ERIC Educational Resources Information Center

Gray, Matt J.; Bolton, Elisa E.; Litz, Brett T.

2004-01-01

Posttraumatic stress disorder (PTSD) typically follows an acute to chronic course. However, some trauma victims do not report significant symptoms until a period of time has elapsed after the event. Although originally dismissed as an artifact of retrospective methodologies, recent prospective studies document apparent instances of delayed-onset…

David Blackwell’s Forty Years in the Idaho Desert, The Foundation for 21st Century Geothermal Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

McLing, Travis; McCurry, Mike; Cannon, Cody

Dr. David Blackwell has had a profound influence on geo-thermal exploration and R&D in Idaho. Forty years have elapsed since the first Southern Methodist University (SMU) temperature logging truck rolled onto the high desert in Southern Idaho, yet even after so much time has elapsed, most recent and ongoing geothermal R&D can trace its roots to the foundational temperature studies led by Dr. Blackwell. We believe that the best way to honor any scientist is to see their work carried forward by others. As this paper demonstrates, it has been an easy task to find a host of Idaho researchersmore » and students eager to contribute to this tribute paper. We organize this paper by ongoing or recent projects that continue to benefit left to Idaho by Dr. David Blackwell.« less

Time-decreasing hazard and increasing time until the next earthquake

DOE Office of Scientific and Technical Information (OSTI.GOV)

Corral, Alvaro

2005-01-01

The existence of a slowly always decreasing probability density for the recurrence times of earthquakes in the stationary case implies that the occurrence of an event at a given instant becomes more unlikely as time since the previous event increases. Consequently, the expected waiting time to the next earthquake increases with the elapsed time, that is, the event moves away fast to the future. We have found direct empirical evidence of this counterintuitive behavior in two worldwide catalogs as well as in diverse regional catalogs. Universal scaling functions describe the phenomenon well.

Efficiency of performing pulmonary procedures in a shared endoscopy unit: procedure time, turnaround time, delays, and procedure waiting time.

PubMed

Verma, Akash; Lee, Mui Yok; Wang, Chunhong; Hussein, Nurmalah B M; Selvi, Kalai; Tee, Augustine

2014-04-01

The purpose of this study was to assess the efficiency of performing pulmonary procedures in the endoscopy unit in a large teaching hospital. A prospective study from May 20 to July 19, 2013, was designed. The main outcome measures were procedure delays and their reasons, duration of procedural steps starting from patient's arrival to endoscopy unit, turnaround time, total case durations, and procedure wait time. A total of 65 procedures were observed. The most common procedure was BAL (61%) followed by TBLB (31%). Overall procedures for 35 (53.8%) of 65 patients were delayed by ≥ 30 minutes, 21/35 (60%) because of "spillover" of the gastrointestinal and surgical cases into the time block of pulmonary procedure. Time elapsed between end of pulmonary procedure and start of the next procedure was ≥ 30 minutes in 8/51 (16%) of cases. In 18/51 (35%) patients there was no next case in the room after completion of the pulmonary procedure. The average idle time of the room after the end of pulmonary procedure and start of next case or end of shift at 5:00 PM if no next case was 58 ± 53 minutes. In 17/51 (33%) patients the room's idle time was >60 minutes. A total of 52.3% of patients had the wait time >2 days and 11% had it ≥ 6 days, reason in 15/21 (71%) being unavailability of the slot. Most pulmonary procedures were delayed due to spillover of the gastrointestinal and surgical cases into the block time allocated to pulmonary procedures. The most common reason for difficulty encountered in scheduling the pulmonary procedure was slot unavailability. This caused increased procedure waiting time. The strategies to reduce procedure delays and turnaround times, along with improved scheduling methods, may have a favorable impact on the volume of procedures performed in the unit thereby optimizing the existing resources.

A potential approach for low flow selection in water resource supply and management

NASA Astrophysics Data System (ADS)

Ouyang, Ying

2012-08-01

SummaryLow flow selections are essential to water resource management, water supply planning, and watershed ecosystem restoration. In this study, a new approach, namely the frequent-low (FL) approach (or frequent-low index), was developed based on the minimum frequent-low flow or level used in minimum flows and/or levels program in northeast Florida, USA. This FL approach was then compared to the conventional 7Q10 approach for low flow selections prior to its applications, using the USGS flow data from the freshwater environment (Big Sunflower River, Mississippi) as well as from the estuarine environment (St. Johns River, Florida). Unlike the FL approach that is associated with the biological and ecological impacts, the 7Q10 approach could lead to the selections of extremely low flows (e.g., near-zero flows) that may hinder its use for establishing criteria to prevent streams from significant harm to biological and ecological communities. Additionally, the 7Q10 approach could not be used when the period of data records is less than 10 years by definition while this may not the case for the FL approach. Results from both approaches showed that the low flows from the Big Sunflower River and the St. Johns River decreased as time elapsed, demonstrating that these two rivers have become drier during the last several decades with a potential of salted water intrusion to the St. Johns River. Results from the FL approach further revealed that the recurrence probability of low flow increased while the recurrence interval of low flow decreased as time elapsed in both rivers, indicating that low flows occurred more frequent in these rivers as time elapsed. This report suggests that the FL approach, developed in this study, is a useful alternative for low flow selections in addition to the 7Q10 approach.

A decade of safety-related regulatory action in the Netherlands: a retrospective analysis of direct healthcare professional communications from 1999 to 2009.

PubMed

Mol, Peter G M; Straus, Sabine M J M; Piening, Sigrid; de Vries, Jonie T N; de Graeff, Pieter A; Haaijer-Ruskamp, Flora M

2010-06-01

As pre-approval trials are inherently limited in assessing the complete benefit-risk profile of a new drug, serious safety issues may emerge once a drug gains widespread use after approval. Regulators face the dilemma of balancing timely market access with the need for complete data on risks. This challenge has led to a life-cycle approach but, so far, few data are available on post-approval safety issues requiring regulatory action. The aim of this study is to determine the frequency, timing and nature of safety issues that necessitated safety-related regulatory action in the form of a Direct Healthcare Professional Communication (DHPC) issued by pharmaceutical companies in collaboration with the Dutch Medicines Evaluation Board during the past decade. All DHPCs issued in the Netherlands from 1 January 1999 to 1 January 2009 were retrospectively collected from the national regulatory authorities. Elapsed time between the approval date and the issue of the DHPC was determined. Characteristics of the action including the nature of the safety issue (according to Medical Dictionary for Regulatory Activities [MedDRA] terminology), type of drug and procedural aspects of the regulatory action taken were reviewed. DHPC characteristics were tabulated and explorative non-parametric tests were performed to study the effect of safety issue, drug class, drug type, orphan drug and first-in-class status on elapsed time from approval to the DHPC. 157 DHPCs were issued concerning 112 different active substances, approximately 9% (112/1200) of active substances available in the Netherlands in 2007. The number of DHPCs issued increased by 2.1 (95% CI 1.2, 3.1; p < 0.001) DHPCs per year over the past decade, reaching a total of 25 in 2008. The median time between approval and DHPC was 5.3 years (range 0.13-48 years). No significant trend in elapsed time to DHPC was observed in relation to the studied years (p = 0.06). One-third of all DHPCs were issued in the first 3 years after approval, but 27% (n = 43/157) of the DHPCs were issued 10 or more years after approval. Timing of DHPCs differed depending on safety issue, drug class, drug type and orphan drug status. DHPCs mostly concerned adverse events in the system organ class of 'cardiac disorders' (15%), 'injury, poisoning and procedural complications' (13%) and 'general disorders and administration site conditions' (10%). In ten cases the drug was eventually withdrawn. Withdrawal occurred a median duration of 2.4 years after registration (range of 1.5-48 years) and was most frequently due to cardiac disorders (including QT interval prolongation; four occasions) and hepatobiliary disorders (two occasions). In the past decade, the number of DHPCs has increased over time. This is likely caused by a multitude of factors: increased risk awareness by the public, media, regulators and other stakeholders; the type of drugs approved, such as orphan drugs and biologicals; and the regulatory process, including conditional approvals. The number of DHPCs may in the future increase further with the possibility of screening large epidemiological databases proactively for adverse drug events. Nine percent of all marketed drugs required a safety-related action. Regulatory action is taken shortly (<3 years) after market approval nearly as often as after intermediate (3-10 years) and long-term (>10 years) market exposure. These findings underline the need for risk management during the whole life cycle of a drug.

Throughput times for adults and children during two drive-through influenza vaccination clinics.

PubMed

Banks, Laura L; Crandall, Cameron; Esquibel, Luke

2013-04-01

Successful planning for public health emergencies requires knowledge of effective methods for mass distribution of medication and supplies to the public. We measured the time required for the key components of 2 drive-through vaccination clinics and summarized the results as they applied to providing medical countermeasures to large populations of children and adults. We hypothesized that vaccinating children in addition to adults would affect throughput time. Using 2 separate drive-through vaccination clinics, we measured elapsed time for vehicle flow and vaccination procedures. We calculated the median length of stay and the time to administer vaccinations based on the number of individual vaccinations given per vehicle, and compared the vehicles in which children (aged 9-18 years) were vaccinated to those in which only adults were vaccinated. A total of 2174 vaccinations and 1275 vehicles were timed during the 2 clinics. The number of vaccinations and vehicles per hour varied during the course of the day; the maximums were 200 and 361 per hour, respectively. The median throughput time was 5 minutes, and the median vaccination time was 48 seconds. Flow over time varied by the hour, and the optimum number of vaccinations per vehicle to maximize efficiency was between 3 and 4. Our findings showed that the presence of children raised the total number of vaccinations given per vehicle and, therefore, the total vaccination processing time per vehicle. However, the median individual procedure time in the vehicles with children was not significantly increased, indicating no need to calculate increased times for processing children 9 years of age or older during emergency planning. Drive-through clinics can provide a large number of seasonal influenza vaccinations in a relatively efficient manner; provide needed experience for students and practitioners in techniques for mass administration of medical countermeasures; and assist public health and emergency management personnel with disaster planning. Including children older than 9 years does not reduce efficiency. (Disaster Med Public Health Preparedness. 2013;0:1-7).

Consequences of varied soil hydraulic and meteorological complexity on unsaturated zone time lag estimates.

PubMed

Vero, S E; Ibrahim, T G; Creamer, R E; Grant, J; Healy, M G; Henry, T; Kramers, G; Richards, K G; Fenton, O

2014-12-01

The true efficacy of a programme of agricultural mitigation measures within a catchment to improve water quality can be determined only after a certain hydrologic time lag period (subsequent to implementation) has elapsed. As the biophysical response to policy is not synchronous, accurate estimates of total time lag (unsaturated and saturated) become critical to manage the expectations of policy makers. The estimation of the vertical unsaturated zone component of time lag is vital as it indicates early trends (initial breakthrough), bulk (centre of mass) and total (Exit) travel times. Typically, estimation of time lag through the unsaturated zone is poor, due to the lack of site specific soil physical data, or by assuming saturated conditions. Numerical models (e.g. Hydrus 1D) enable estimates of time lag with varied levels of input data. The current study examines the consequences of varied soil hydraulic and meteorological complexity on unsaturated zone time lag estimates using simulated and actual soil profiles. Results indicated that: greater temporal resolution (from daily to hourly) of meteorological data was more critical as the saturated hydraulic conductivity of the soil decreased; high clay content soils failed to converge reflecting prevalence of lateral component as a contaminant pathway; elucidation of soil hydraulic properties was influenced by the complexity of soil physical data employed (textural menu, ROSETTA, full and partial soil water characteristic curves), which consequently affected time lag ranges; as the importance of the unsaturated zone increases with respect to total travel times the requirements for high complexity/resolution input data become greater. The methodology presented herein demonstrates that decisions made regarding input data and landscape position will have consequences for the estimated range of vertical travel times. Insufficiencies or inaccuracies regarding such input data can therefore mislead policy makers regarding the achievability of water quality targets. Copyright © 2014 Elsevier B.V. All rights reserved.

Time Management in the Operating Room: An Analysis of the Dedicated Minimally Invasive Surgery Suite

PubMed Central

Hsiao, Kenneth C.; Machaidze, Zurab

2004-01-01

Background: Dedicated minimally invasive surgery suites are available that contain specialized equipment to facilitate endoscopic surgery. Laparoscopy performed in a general operating room is hampered by the multitude of additional equipment that must be transported into the room. The objective of this study was to compare the preparation times between procedures performed in traditional operating rooms versus dedicated minimally invasive surgery suites to see whether operating room efficiency is improved in the specialized room. Methods: The records of 50 patients who underwent laparoscopic procedures between September 2000 and April 2002 were retrospectively reviewed. Twenty-three patients underwent surgery in a general operating room and 18 patients in an minimally invasive surgery suite. Nine patients were excluded because of cystoscopic procedures undergone prior to laparoscopy. Various time points were recorded from which various time intervals were derived, such as preanesthesia time, anesthesia induction time, and total preparation time. A 2-tailed, unpaired Student t test was used for statistical analysis. Results: The mean preanesthesia time was significantly faster in the minimally invasive surgery suite (12.2 minutes) compared with that in the traditional operating room (17.8 minutes) (P=0.013). Mean anesthesia induction time in the minimally invasive surgery suite (47.5 minutes) was similar to time in the traditional operating room (45.7 minutes) (P=0.734). The average total preparation time for the minimally invasive surgery suite (59.6 minutes) was not significantly faster than that in the general operating room (63.5 minutes) (P=0.481). Conclusion: The amount of time that elapses between the patient entering the room and anesthesia induction is statically shorter in a dedicated minimally invasive surgery suite. Laparoscopic surgery is performed more efficiently in a dedicated minimally invasive surgery suite versus a traditional operating room. PMID:15554269

The Employment Impact of Technological Change. Technology and the American Economy, Appendix Volume II.

ERIC Educational Resources Information Center

National Commission on Technology, Automation and Economic Progress, Washington, DC.

Eleven descriptive studies prepared by independent experts and dealing with the employment impact of technological change are presented. Part I contains (1) an analysis, at the establishment level, of employment-increasing growth of output and employment-decreasing growth of output per man-hour, (2) case studies of the elapsed time involved in the…

Orson Scott Card's "Ender and Bean": The Exceptional Child as Hero

ERIC Educational Resources Information Center

Doyle, Christine

2004-01-01

Orson Scott Card's school stories in outer space, "Ender's Game" and "Ender's Shadow," purportedly occur at the same time and tell the "same" story, but from the perspectives of two different child protagonists. Scenes in "Ender's Shadow" even reproduce text from "Ender's Game." Nevertheless, 14 years elapsed between the publications of the two…

40 CFR 86.1319-90 - CVS calibration.

Code of Federal Regulations, 2010 CFR

2010-07-01

... with such a device.) The CVS calibration procedures are designed for use of a “metering venturi” type... series with the pump. (ii) The calculated flow rate, ft 3/min, (at pump inlet absolute pressure and... during test period N Revs ±1 Rev. Elapsed time for test period t sec. ±0.5 sec. (5) After the system has...

40 CFR 86.1319-90 - CVS calibration.

Code of Federal Regulations, 2013 CFR

2013-07-01

... with such a device.) The CVS calibration procedures are designed for use of a “metering venturi” type... series with the pump. (ii) The calculated flow rate, ft 3/min, (at pump inlet absolute pressure and... test period N Revs ±1 Rev. Elapsed time for test period t sec. ±0.5 sec. (5) After the system has been...

40 CFR 86.1319-90 - CVS calibration.

Code of Federal Regulations, 2011 CFR

2011-07-01

... with such a device.) The CVS calibration procedures are designed for use of a “metering venturi” type... series with the pump. (ii) The calculated flow rate, ft 3/min, (at pump inlet absolute pressure and... during test period N Revs ±1 Rev. Elapsed time for test period t sec. ±0.5 sec. (5) After the system has...

40 CFR 86.1319-90 - CVS calibration.

Code of Federal Regulations, 2012 CFR

2012-07-01

... with such a device.) The CVS calibration procedures are designed for use of a “metering venturi” type... series with the pump. (ii) The calculated flow rate, ft 3/min, (at pump inlet absolute pressure and... test period N Revs ±1 Rev. Elapsed time for test period t sec. ±0.5 sec. (5) After the system has been...

Autism and Autism Spectrum Disorders: Diagnostic Issues for the Coming Decade

ERIC Educational Resources Information Center

Volkmar, Fred R.; State, Matthew; Klin, Ami

2009-01-01

A decade and a half have elapsed since DSM-IV and ICD-10 appeared. During this time the convergent definitions of autism and related disorders in these two diagnostic systems have stimulated tremendous research. In this brief review we summarize areas of progress and continuing controversy, including approaches to diagnosis in more cognitively…

Higher Education, Changing Labour Market and Social Mobility in the Era of Massification in China

ERIC Educational Resources Information Center

Mok, Ka Ho; Wu, Alfred M.

2016-01-01

This article attempts to investigate the relationship between the massification of higher education, labour market and social mobility in contemporary China. Though only a short period of time has elapsed from elite to mass education, China's higher education has been characterised as a wide, pervasive massification process. Similar to other East…

75 FR 19646 - Notice of Revocation of Market-Based Rate Tariff

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-15

... Docket No. ER07-514-000. NCSU Energy, Inc Docket No. ER07-177-000. Primary Power Marketing LLC.. Docket... Order, the Commission directed G&G Energy, Inc.; NCSU Energy, Inc.; Primary Power Marketing LLC. and... time period for compliance with the March 18 Order has elapsed. The four companies identified in the...

Woodlark Island in Solomon Sea as seen from the Apollo 7 spacecraft

NASA Image and Video Library

1968-10-21

AS07-04-1609 (21 Oct. 1968) --- Woodlark Island in the Solomon Sea, east of New Guinea and northeast of Australia, as seen from the Apollo 7 spacecraft during its 158th revolution of Earth. Photographed from an altitude of 140 nautical miles, at ground elapsed time of 251 hours and 21 minutes.

Using Playing Cards to Simulate a Molecular Clock

ERIC Educational Resources Information Center

Westerling, Karin E.

2008-01-01

Changes in DNA base-repair may serve as an indicator of the time elapsed since divergence from a common ancestor. DNA sequences can now be analyzed. The simulation presented in this article allows students to observe the accumulation of changes in a randomly mutating sequence of playing cards. The cards are analogous to DNA nucleotide or protein…

26 CFR 1.410(a)-9T - Elapsed time (temporary).

Code of Federal Regulations, 2010 CFR

2010-04-01

... prescribed in this paragraph, may disregard any remaining less than whole year, 12-month or 365-day period of... (temporary). (a)-(b) [Reserved] (c) Eligibility to participate. (1) [Reserved] (2) Determination of one-year period of service. (i) [Reserved] (ii) For purposes of section 410(a)(1)(B)(i), a “2-year period of...

Exercise Programming for Cardiacs--A New Direction for Physical Therapists.

ERIC Educational Resources Information Center

Gutin, Bernard

This speech begins with the presentation of a conceptual scheme of the physical working capacity of a person starting a training program. The scheme shows that after exercise, when recovery begins and sufficient time elapses, the individual recovers and adapts to a level of physical working capacity which is higher than his starting level. From…

The Influence of Transfer System Factors and Training Elapsed Time on Transfer in a Healthcare Organization

ERIC Educational Resources Information Center

Mihalko, Beverly J.

2010-01-01

Organizations and other sponsors of training face increasing pressure to demonstrate the value or impact of their training programs on individual and organizational performance. A critical element in the validation of training effectiveness is the permanent transfer of learned knowledge, skills, and behaviors to the workplace. The generalization…

Brunei English: A Developing Variety

ERIC Educational Resources Information Center

O'Hara-Davies, Breda

2010-01-01

A considerable amount of time has elapsed since the existence of a distinct variety of English, Brunei English (BNE), was mooted in the early 1990s. A subsequent study conducted by Svalberg in 1998 suggested that BNE was then in its infancy and that its speakers were largely unaware of the differences between it and Standard British English (STE).…

Tuamotu Archipelago in South Pacific as seen from the Apollo 7 spacecraft

NASA Image and Video Library

1968-10-21

AS07-04-1590 (20 Oct. 1968) --- Tuamotu Archipelago in the South Pacific Ocean, looking southwest, as photographed from the Apollo 7 spacecraft during its 141st revolution of Earth. The photograph was taken from an altitude of 110 nautical miles, at a ground elapsed time of 224 hours and 18 minutes.

Seismic hazard assessment over time: Modelling earthquakes in Taiwan

NASA Astrophysics Data System (ADS)

Chan, Chung-Han; Wang, Yu; Wang, Yu-Ju; Lee, Ya-Ting

2017-04-01

To assess the seismic hazard with temporal change in Taiwan, we develop a new approach, combining both the Brownian Passage Time (BPT) model and the Coulomb stress change, and implement the seismogenic source parameters by the Taiwan Earthquake Model (TEM). The BPT model was adopted to describe the rupture recurrence intervals of the specific fault sources, together with the time elapsed since the last fault-rupture to derive their long-term rupture probability. We also evaluate the short-term seismicity rate change based on the static Coulomb stress interaction between seismogenic sources. By considering above time-dependent factors, our new combined model suggests an increased long-term seismic hazard in the vicinity of active faults along the western Coastal Plain and the Longitudinal Valley, where active faults have short recurrence intervals and long elapsed time since their last ruptures, and/or short-term elevated hazard levels right after the occurrence of large earthquakes due to the stress triggering effect. The stress enhanced by the February 6th, 2016, Meinong ML 6.6 earthquake also significantly increased rupture probabilities of several neighbouring seismogenic sources in Southwestern Taiwan and raised hazard level in the near future. Our approach draws on the advantage of incorporating long- and short-term models, to provide time-dependent earthquake probability constraints. Our time-dependent model considers more detailed information than any other published models. It thus offers decision-makers and public officials an adequate basis for rapid evaluations of and response to future emergency scenarios such as victim relocation and sheltering.

Muses on the Gregorian Calendar

ERIC Educational Resources Information Center

Staples, Ed

2013-01-01

This article begins with an exploration of the origins of the Gregorian Calendar. Next it describes the function of school inspector Christian Zeller (1822-1899) used to determine the number of the elapsed days of a year up to and including a specified date and how Zeller's function can be used to determine the number of days that have elapsed in…

Impact of water quality on chlorine demand of corroding copper.

PubMed

Lytle, Darren A; Liggett, Jennifer

2016-04-01

Copper is widely used in drinking water premise plumbing system materials. In buildings such as hospitals, large and complicated plumbing networks make it difficult to maintain good water quality. Sustaining safe disinfectant residuals throughout a building to protect against waterborne pathogens such as Legionella is particularly challenging since copper and other reactive distribution system materials can exert considerable demands. The objective of this work was to evaluate the impact of pH and orthophosphate on the consumption of free chlorine associated with corroding copper pipes over time. A copper test-loop pilot system was used to control test conditions and systematically meet the study objectives. Chlorine consumption trends attributed to abiotic reactions with copper over time were different for each pH condition tested, and the total amount of chlorine consumed over the test runs increased with increasing pH. Orthophosphate eliminated chlorine consumption trends with elapsed time (i.e., chlorine demand was consistent across entire test runs). Orthophosphate also greatly reduced the total amount of chlorine consumed over the test runs. Interestingly, the total amount of chlorine consumed and the consumption rate were not pH dependent when orthophosphate was present. The findings reflect the complex and competing reactions at the copper pipe wall including corrosion, oxidation of Cu(I) minerals and ions, and possible oxidation of Cu(II) minerals, and the change in chlorine species all as a function of pH. The work has practical applications for maintaining chlorine residuals in premise plumbing drinking water systems including large buildings such as hospitals. Published by Elsevier Ltd.

Automatic transponder. [measurement of the internal delay time of a transponder

NASA Technical Reports Server (NTRS)

Anderson, R. E.; Brisken, A. F.; Lewis, J. R. (Inventor)

1977-01-01

A method and apparatus for the automatic, remote measurement of the internal delay time of a transponder at the time of operation is provided. A small portion of the transmitted signal of the transponder is converted to the receive signal frequency of the transponder and supplied to the input of the transponder. The elapsed time between the receive signal locally generated and the receive signal causing the transmission of the transmitted signal is measured, said time being representative of or equal to the internal delay time of the transponder at the time of operation.

Spatial Patterns of Geomorphic Surface Features and Fault Morphology Based on Diffusion Equation Modeling of the Kumroch Fault Kamchatka Peninsula, Russia

NASA Astrophysics Data System (ADS)

Heinlein, S. N.

2013-12-01

Remote sensing data sets are widely used for evaluation of surface manifestations of active tectonics. This study utilizes ASTER GDEM and Landsat ETM+ data sets with Google Earth images draped over terrain models. This study evaluates 1) the surrounding surface geomorphology of the study area with these data sets and 2) the morphology of the Kumroch Fault using diffusion modeling to estimate constant diffusivity (κ) and estimate slip rates by means of real ground data measured across fault scarps by Kozhurin et al. (2006). Models of the evolution of fault scarp morphology provide time elapsed since slip initiated on a faults surface and may therefore provide more accurate estimates of slip rate than the rate calculated by dividing scarp offset by the age of the ruptured surface. Profile modeling of scarps collected by Kozhurin et al. (2006) formed by several events distributed through time and were evaluated using a constant slip rate (CSR) solution which yields a value A/κ (1/2 slip rate/diffusivity). Time elapsed since slip initiated on the fault is determined by establishing a value for κ and measuring total scarp offset. CSR nonlinear modeling estimated of κ range from 8m2/ka - 14m2/ka on the Kumroch Fault which indicates a slip rates of 0.6 mm/yr - 1.0 mm/yr since 3.4 ka -3.7 ka. This method provides a quick and inexpensive way to gather data for a regional tectonic study and establish estimated rates of tectonic activity. Analyses of the remote sensing data are providing new insight into the role of active tectonics within the region. Results from fault scarp diffusion models of Mattson and Bruhn (2001) and DuRoss and Bruhn (2004) and Kozhurin et al. (2006), Kozhurin (2007), Kozhurin et al. (2008) and Pinegina et al. 2012 trench profiles of the KF as calibrated age fault scarp diffusion rates were estimated. (-) mean that no data could be determined.

A New Equation for Predicting Evolution of Oral Pain in Orthodontic Treatment: A Longitudinal, Prospective Cohort Study.

PubMed

Larrea, Monica; Salvador, Rosario; Cibrian, Rosa; Gandia, Jose Luis; Paredes-Gallardo, Vanessa

2017-01-01

To develop an equation capable of relating the evolution of oral pain to the time elapsed, measured from the moment of dental archwire fitting and identifying when pain begins, peaks, and ends; and secondly, to compare pain during orthodontic treatment in relation to archwire material (steel or nickel-titanium [Ni-Ti]) and position (maxillary or mandibular) and patient age (child, teenager, or adult) and gender (male or female). A longitudinal prospective cohort study was conducted of 112 patients who filled in a scale to evaluate pain, noting the times when the pain occurred. The total sample consisted of 60 males and 52 females with a mean (± standard deviation [SD]) age of 19.8 ± 6.2 years. The sample was divided into five groups depending on archwire material and position, and patient age and gender. A univariate four-way ANOVA model was performed to compare mean pain levels between groups. Bonferroni test was used for multiple comparisons. A univariate nonlinear regression model was carried out for pain level, 95% confidence intervals (95% CI) were calculated, and the statistic R² was used. An equation was developed based on pain levels in relation to time elapsed, measured from the moment when the archwire had been fitted in the mouth. The equation had three coefficients related to mean pain values: overall pain, peak pain, and how pain decreased. It fitted all study groups with a correlation coefficient > 0.9. The model showed that pain levels were influenced by archwire material and patient gender and age, but not archwire position. The equation reproduced the data registered and can be applied to studies of pain derived from archwires, and this methodology could be used for other external agents fitted in the mouth. Patients receiving dental treatment involving external agents can be made aware of the pain they can expect to experience. This will enable them to distinguish expected pain from other pain, which will help them identify other pathologies requiring medical attention and to approach treatment with better motivation since the pattern of pain evolution is known in advance.

Phosphorus leaching from soils amended with thermally gasified piggery waste ash.

PubMed

Kuligowski, Ksawery; Poulsen, Tjalfe Gorm

2009-09-01

In regions with intensive livestock farming, thermal treatment for local energy extraction from the manure and export of the P rich ash as a fertilizer has gained interest. One of the main risks associated with P fertilizers is eutrophication of water bodies. In this study P and K mobility in ash from anaerobically digested, thermally gasified (GA) and incinerated (IA) piggery waste has been tested using water loads ranging from 0.1 to 200 ml g(-1). Leaching of P from soil columns amended with GA was investigated for one P application rate (205 kg P ha(-1) corresponding to 91 mg P kg(-1) soil dry matter) as a function of precipitation rate (9.5 and 2.5 mm h(-1)), soil type (Jyndevad agricultural soil and sand), amount of time elapsed between ash amendment and onset of precipitation (0 and 5 weeks) and compared to leaching from soils amended with a commercial fertilizer (Na(2)HPO(4)). Water soluble P in GA and IA constituted 0.04% and 0.8% of total ash P. Ash amended soil released much less P (0.35% of total P applied in sand) than Na(2)HPO(4) (97% and 12% of total P applied in Jyndevad and sand, respectively).

Effects of pumice mining on soil quality

NASA Astrophysics Data System (ADS)

Cruz-Ruíz, A.; Cruz-Ruíz, E.; Vaca, R.; Del Aguila, P.; Lugo, J.

2016-01-01

Mexico is the world's fourth most important maize producer; hence, there is a need to maintain soil quality for sustainable production in the upcoming years. Pumice mining is a superficial operation that modifies large areas in central Mexico. The main aim was to assess the present state of agricultural soils differing in elapsed time since pumice mining (0-15 years) in a representative area of the Calimaya region in the State of Mexico. The study sites in 0, 1, 4, 10, and 15 year old reclaimed soils were compared with an adjacent undisturbed site. Our results indicate that gravimetric moisture content, water hold capacity, bulk density, available phosphorus, total nitrogen, soil organic carbon, microbial biomass carbon and phosphatase and urease activity were greatly impacted by disturbance. A general trend of recovery towards the undisturbed condition with reclamation age was found after disturbance, the recovery of soil total N being faster than soil organic C. The soil quality indicators were selected using principal component analysis (PCA), correlations and multiple linear regressions. The first three components gathered explain 76.4 % of the total variability. The obtained results revealed that the most appropriate indicators to diagnose the quality of the soils were urease, available phosphorus and bulk density and minor total nitrogen. According to linear score analysis and the additive index, the soils showed a recuperation starting from 4 years of pumice extraction.

Cytogenetic analysis of children under long-term antibacterial therapy with nitroheterocyclic compound furagin.

PubMed

Slapsyte, G; Jankauskiene, A; Mierauskiene, J; Lazutka, J R

2001-04-05

Cytogenetic analysis of chromosome aberrations (CAs) and sister chromatid exchanges (SCEs) was performed in 109 blood samples from 95 pediatric patients with urinary tract infections (UTIs). Children were exposed to diagnostic levels of X-rays during voiding cystourethrography and subsequently treated for one to 12 months with low doses of furagin - N-(5-nitro-2-furyl)-allylidene-1-aminohydantoin. Furagin is 2-substituted 5-nitrofuran, chemically and structurally similar to well-known antibacterial compound nitrofurantoin. Increased frequencies of CAs were found in children undergoing voiding cystourethrography as compared with the unexposed, acentric fragments being the most frequent alteration (2.03 versus 0.88 per 100 cells, P=0.006). However, a significant decrease in the frequency of acentric fragments was determined with the time elapsed since X-ray examination was performed. A time-independent increase in SCE frequency was found in lymphocytes of children treated with furagin. Total CA frequency did not differ significantly between groups of children with various duration of furagin treatment. However, frequency of chromatid exchanges (triradials and quadriradials) increased significantly with duration of treatment.

Aging of the field-induced asymmetry in a disordered ferroelectric

NASA Astrophysics Data System (ADS)

Bonello, B.; Doussineau, P.; Dupuis, V.; Levelut, A.

2006-07-01

The isothermal aging of the asymmetry induced in the disordered dielectric crystal KTa_{1-x} Nbx O3 (x=0.027) submitted to the biasing electric field E, is investigated. To this end, the response of the complex dielectric constant to infinitesimal field changes δ{E}, applied to the sample after a variable aging delay, has been measured for different magnitudes of E and after different aging delays. Two different experimental procedures have been used: in both cases the response strongly depends on the time spent under field. For short aging delays, the response has a strong contribution proportional to δE and a weak quadratic contribution proportional to left({δ E}right)^2. As time elapses, the linear and the quadratic contributions age in opposite ways: the former decreases whereas the latter increases. This paradoxical behaviour is analyzed in the framework of a model which attributes aging and the related effects (rejuvenation, memory) to the evolution of polarization domain walls: the decrease of the linear contribution is related to the decrease of the total wall area, while the increase of the quadratic term is attributed to wall reconformations.

Time perception, pacing and exercise intensity: maximal exercise distorts the perception of time.

PubMed

Edwards, A M; McCormick, A

2017-10-15

Currently there are no data examining the impact of exercise on the perception of time, which is surprising as optimal competitive performance is dependent on accurate pacing using knowledge of time elapsed. With institutional ethics approval, 12 recreationally active adult participants (f=7, m=5) undertook both 30s Wingate cycles and 20min (1200s) rowing ergometer bouts as short and long duration self-paced exercise trials, in each of three conditions on separate occasions: 1) light exertion: RPE 11, 2) heavy exertion: RPE 15, 3) maximal exertion: RPE 20. Participants were unaware of exercise duration and were required to verbally indicate when they perceived (subjective time) 1) 25%, 2) 50%, 3) 75% and 4) 100% of each bout's measured (chronological) time had elapsed. In response to the Wingate task, there was no difference between durations of subjective time at the 25%, nor at the 50% interval. However, at the 75% and 100% intervals, the estimate for the RPE 20 condition was shortest (P<0.01). In response to rowing, there were no differences at the 25% interval, but there was some evidence that the RPE 20 condition was perceived shorter at 50%. At 75% and 100%, the RPE 20 condition was perceived to be shorter than both RPE 15 (P=0.04) and RPE 11 (P=0.008) conditions. This study is the first to empirically demonstrate that exercise intensity distorts time perception, particularly during maximal exercise. Consequently external feedback of chronological time may be an important factor for athletes undertaking maximal effort tasks or competitions. Copyright © 2017 Elsevier Inc. All rights reserved.

Diffusion of liquid polystyrene into glassy poly(phenylene oxide) characterized by DSC

NASA Astrophysics Data System (ADS)

Li, Linling; Wang, Xiaoliang; Zhou, Dongshan; Xue, Gi

2013-03-01

We report a diffusion study on the polystyrene/poly(phenylene oxide) (PS/PPO) mixture consisted by the PS and PPO nanoparticles. Diffusion of liquid PS into glassy PPO (l-PS/g-PPO) is promoted by annealing the PS/PPO mixture at several temperatures below Tg of the PPO. By tracing the Tgs of the PS-rich domain behind the diffusion front using DSC, we get the relationships of PS weight fractions and diffusion front advances with the elapsed diffusion times at different diffusion temperatures using the Gordon-Taylor equation and core-shell model. We find that the plots of weight fraction of PS vs. elapsed diffusion times at different temperatures can be converted to a master curve by Time-Temperature superposition, and the shift factors obey the Arrhenius equation. Besides, the diffusion front advances of l-PS into g-PPO show an excellent agreement with the t1/2 scaling law at the beginning of the diffusion process, and the diffusion coefficients of different diffusion temperatures also obey the Arrhenius equation. We believe the diffusion mechanism for l-PS/g-PPO should be the Fickean law rather than the Case II, though there are departures of original linearity at longer diffusion times due to the limited liquid supply system. Diffusion of liquid polystyrene into glassy poly(phenylene oxide) characterized by DSC

Red Sea coastal area of Saudi Arabia as seen from the Apollo 7 spacecraft

NASA Image and Video Library

1968-10-15

AS07-07-1774 (15 Oct. 1968) --- Red Sea coastal area of Saudi Arabia as seen from the Apollo 7 spacecraft during its 58th revolution of Earth. This picture shows extent of coral reefs in the Red Sea. Photographed from an altitude of 88 nautical miles, at ground elapsed time of 91 hours and 17 minutes.

Sunrayce 97 Continues Day 2 - Terre Haute to Godfrey

Science.gov Websites

overall lead as Sunrayce 97 completed its second day of running. Their elapsed time for the day was 4:10 :31. Second place went to Massachusetts Institute of Technology, 4:11:27. The two teams are neck-in University-Los Angeles, 4:23:01. The daily Sportsmanship award went to Stanford University/UC - Berkeley for

The Roles of Beaconing and Dead Reckoning in Human Virtual Navigation

ERIC Educational Resources Information Center

Bodily, Kent D.; Daniel, Thomas A.; Sturz, Bradley R.

2012-01-01

Beaconing is a process in which the distance between a visual landmark and current position is reduced in order to return to a location. In contrast, dead reckoning is a process in which vestibular, kinesthetic and/or optic flow cues are utilized to update speed of movement, elapsed time of movement, and direction of movement to return to a…

Pacific coast southwestern Mexico as seen from the Apollo 7 spacecraft

NASA Image and Video Library

1968-10-13

AS07-05-1652 (13 Oct. 1968) --- Pacific coast area of southwestern Mexico, State of Guerrero, from Acapulco to Tecoanapa, as seen from the Apollo 7 spacecraft during its 34th revolution of Earth. Photographed from an altitude of 125 nautical miles, at ground elapsed time of 54 hours and 10 minutes. Much cloud cover in area.

Gulf of Mexico, coast of Yucatan, as seen from the Apollo 7 spacecraft

NASA Image and Video Library

1968-10-13

AS07-05-1635 (13 Oct. 1968) --- Gulf of Mexico, coast of Yucatan, Mexico, as seen from the Apollo 7 spacecraft during its 33rd revolution of Earth. Note road leading to city of Merida which is under cloud cover. Photographed from an altitude of 123 nautical miles, at ground elapsed time of 52 hours and 37 minutes.

Associations and Dissociations of Transitive and Intransitive Gestures in Left and Right Hemisphere Stroke Patients

ERIC Educational Resources Information Center

Stamenova, Vessela; Roy, Eric A.; Black, Sandra E.

2010-01-01

The study investigated performance on pantomime and imitation of transitive and intransitive gestures in 80 stroke patients, 42 with left (LHD) and 38 with right (RHD) hemisphere damage. Patients were also categorized in two groups based on the time that has elapsed between their stroke and the apraxia assessment: acute-subacute (n = 42) and…

77 FR 35662 - Intent To Prepare a Draft Supplemental Environmental Impact Statement for the Greenup Locks and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-14

... project in April 2000. This study recommended a 600- foot (ft) extension of the existing auxiliary lock chamber to a length of 1200 ft. The project was authorized by Congress in 2000; however, no funds have been appropriated for project construction. Due to the amount of time that has elapsed since completion...

Lexical and Grammatical Abilities in Deaf Italian Preschoolers: The Role of Duration of Formal Language Experience

ERIC Educational Resources Information Center

Rinaldi, Pasquale; Caselli, Cristina

2009-01-01

We evaluated language development in deaf Italian preschoolers with hearing parents, taking into account the duration of formal language experience (i.e., the time elapsed since wearing a hearing aid and beginning language education) and different methods of language education. Twenty deaf children were matched with 20 hearing children for age and…

Sunrayce 97 Continues Day 4 - Fulton to Lee's Summit

Science.gov Websites

(202) 586-0713 Lee's Summit, MO -- Massachusetts Institute of Technology (MIT) took Day IV and maintained the overall lead as sunrayce 97 completed its fourth day. The elapsed time for the day for the attaining good sun early enough in the day to replenish the batteries, as such a fast pace will deplete them

Relationship between mozzarella yield and milk composition, processing factors, and recovery of whey constituents.

PubMed

Sales, D C; Rangel, A H N; Urbano, S A; Freitas, Alfredo R; Tonhati, Humberto; Novaes, L P; Pereira, M I B; Borba, L H F

2017-06-01

Our aim was to identify the relationship between mozzarella cheese yield and buffalo milk composition, processing factors, and recovery of whey constituents. A production of 30 batches of mozzarella cheese at a dairy industry in northeast Brazil (Rio Grande do Norte) was monitored between March and November 2015. Mozzarella yield and 32 other variables were observed for each batch, and divided into 3 groups: milk composition variables (12); variables involved in the cheesemaking process (14); and variables for recovery of whey constituents (6). Data were analyzed using descriptive statistics, Pearson correlation, and principal component analysis. Most of the correlations between milk composition variables and between the variables of the manufacturing processes were not significant. Significant correlations were mostly observed between variables for recovery of whey constituents. Yield only showed significant correlation with time elapsed between curd cuttings and age of the starter culture, and it showed greater association with age of the starter culture, time elapsed between curd cuttings, and during stretching, as well as with milk pH and density. Thus, processing factors and milk characteristics are closely related to dairy efficiency in mozzarella manufacturing. Copyright © 2017 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Evaluation of the Sparton tight-tolerance AXBT

NASA Technical Reports Server (NTRS)

Boyd, Janice D.; Linzell, Robert S.

1993-01-01

Forty-six near-simultaneous pairs of conductivity - temperature - depth (CTD) and Sparton 'tight tolerance' air expendable bathythermograph (AXBT) temperature profiles were obtained in summer 1991 from a location in the Sargasso Sea. The data were analyzed to assess the temperature and depth accuracies of the Sparton AXBTs. The tight-tolerance criterion was not achieved using the manufacturer's equations but may have been achieved using customized equations computed from the CTD data. The temperature data from the customized equations had a one standard deviation error of 0.13 C. A customized elapsed fall time-to-depth conversion equation was found to be z = 1.620t - 2.2384 x 10(exp -4) t(exp 2) + 1.291 x 10(exp -7) t(exp 3), with z the depth in meters and t the elapsed fall time after probe release in seconds. The standard deviation of the depth error was about 5 m; a rule of thumb for estimating maximum bounds on the depth error below 100 m could be expressed as +/-2% of depth or +/- 10 m, whichever is greater. This equation gave greater depth accuracy than either the manufacturer's supplied equation or the navy standard equation.

Delay in Diagnosis and Treatment of Breast Cancer among Women Attending a Reference Service in Brazil

PubMed

Romeiro Lopes, Tiara Cristina; Gravena, Angela Andréia França; Demitto, Marcela de Oliveira; Borghesan, Deise Helena Pelloso; Dell`Agnolo, Cátia Millene; Brischiliari, Sheila Cristina Rocha; Carvalho, Maria Dalva de Barros; Pelloso, Sandra Marisa

2017-11-26

Background: Cancer is a major public health problem. Early diagnosis and treatment are essential for reducing mortality. This study aimed to analyze factors associated with delay in breast cancer diagnosis and treatment among women attending a reference cancer service. Methods: This retrospective, cross-sectional study was performed with data collected from medical records and interviews conducted with women diagnosed with breast cancer and treated from October 2013 to October 2014 at a cancer reference hospital in Paraná, Southern Brazil. Results: A total of 82 participants were enrolled during the study period; their average age was 58.2 ± 11.5 years. The average time taken for final diagnosis of breast cancer was 102.5 ± 165.5 days. Treatment onset was delayed in the majority of cases, and the average time elapsing from diagnostic biopsy to onset of primary treatment was 72.3 ± 54.0 days. The odds of treatment delay were higher among the women with a low educational level. Conclusions: The results underline the need for proposals aimed at early detection, identification of risk factors and timely provision of treatment by health managers that focus on this group. Creative Commons Attribution License

The effects of morphine on fixed-interval patterning and temporal discrimination.

PubMed Central

Odum, A L; Schaal, D W

2000-01-01

Changes produced by drugs in response patterns under fixed-interval schedules of reinforcement have been interpreted to result from changes in temporal discrimination. To examine this possibility, this experiment determined the effects of morphine on the response patterning of 4 pigeons during a fixed-interval 1-min schedule of food delivery with interpolated temporal discrimination trials. Twenty of the 50 total intervals were interrupted by choice trials. Pecks to one key color produced food if the interval was interrupted after a short time (after 2 or 4.64 s). Pecks to another key color produced food if the interval was interrupted after a long time (after 24.99 or 58 s). Morphine (1.0 to 10.0 mg/kg) decreased the index of curvature (a measure of response patterning) during fixed intervals and accuracy during temporal discrimination trials. Accuracy was equally disrupted following short and long sample durations. Although morphine disrupted temporal discrimination in the context of a fixed-interval schedule, these effects are inconsistent with interpretations of the disruption of response patterning as a selective overestimation of elapsed time. The effects of morphine may be related to the effects of more conventional external stimuli on response patterning. PMID:11029024

SQL Triggers Reacting on Time Events: An Extension Proposal

NASA Astrophysics Data System (ADS)

Behrend, Andreas; Dorau, Christian; Manthey, Rainer

Being able to activate triggers at timepoints reached or after time intervals elapsed has been acknowledged by many authors as a valuable functionality of a DBMS. Recently, the interest in time-based triggers has been renewed in the context of data stream monitoring. However, up till now SQL triggers react to data changes only, even though research proposals and prototypes have been supporting several other event types, in particular time-based ones, since long. We therefore propose a seamless extension of the SQL trigger concept by time-based triggers, focussing on semantic issues arising from such an extension.

Linear electric field time-of-flight ion mass spectrometer

DOEpatents

Funsten, Herbert O [Los Alamos, NM; Feldman, William C [Los Alamos, NM

2008-06-10

A linear electric field ion mass spectrometer having an evacuated enclosure with means for generating a linear electric field located in the evacuated enclosure and means for injecting a sample material into the linear electric field. A source of pulsed ionizing radiation injects ionizing radiation into the linear electric field to ionize atoms or molecules of the sample material, and timing means determine the time elapsed between ionization of atoms or molecules and arrival of an ion out of the ionized atoms or molecules at a predetermined position.

Establishing Lower Developmental Thresholds for a Common BlowFly: For Use in Estimating Elapsed Time since Death Using Entomologyical Methods

DTIC Science & Technology

2011-10-01

Abstract …….. Forensic entomology is a science used to estimate a post-mortem interval (PMI). Larvae develop at predictable rates and the time interval...Warren,Jodie; DRDC CSS CR 2011-23; Defence R&D Canada – CSS; October 2011. Introduction or background: Forensic entomology is the study of insects...in Europe since the 1850’s. Forensic entomology is now an integral part of a death investigation when estimating a time since death beyond 72 hours

Forecasting Occurrences of Activities.

PubMed

Minor, Bryan; Cook, Diane J

2017-07-01

While activity recognition has been shown to be valuable for pervasive computing applications, less work has focused on techniques for forecasting the future occurrence of activities. We present an activity forecasting method to predict the time that will elapse until a target activity occurs. This method generates an activity forecast using a regression tree classifier and offers an advantage over sequence prediction methods in that it can predict expected time until an activity occurs. We evaluate this algorithm on real-world smart home datasets and provide evidence that our proposed approach is most effective at predicting activity timings.

How Long Should Routine EEG Be Recorded to Get Relevant Information?

PubMed

Doudoux, Hannah; Skaare, Kristina; Geay, Thomas; Kahane, Philippe; Bosson, Jean L; Sabourdy, Cécile; Vercueil, Laurent

2017-03-01

The optimal duration of routine EEG (rEEG) has not been determined on a clinical basis. This study aims to determine the time required to obtain relevant information during rEEG with respect to the clinical request. All rEEGs performed over 3 months in unselected patients older than 14 years in an academic hospital were analyzed retrospectively. The latency required to obtain relevant information was determined for each rEEG by 2 independent readers blinded to the clinical data. EEG final diagnoses and latencies were analyzed with respect to the main clinical requests: subacute cognitive impairment, spells, transient focal neurologic manifestation or patients referred by epileptologists. From 430 rEEGs performed in the targeted period, 364 were analyzed: 92% of the pathological rEEGs were provided within the first 10 minutes of recording. Slowing background activity was diagnosed from the beginning, whereas interictal epileptiform discharges were recorded over time. Moreover, the time elapsed to demonstrate a pattern differed significantly in the clinical groups: in patients with subacute cognitive impairment, EEG abnormalities appeared within the first 10 minutes, whereas in the other groups, data could be provided over time. Patients with subacute cognitive impairment differed from those in the other groups significantly in the elapsed time required to obtain relevant information during rEEG, suggesting that 10-minute EEG recordings could be sufficient, arguing in favor of individualized rEEG. However, this conclusion does not apply to intensive care unit patients.

A fast and robust bulk-loading algorithm for indexing very large digital elevation datasets II. Experimental results

NASA Astrophysics Data System (ADS)

Rodríguez, Félix R.; Barrena, Manuel

2011-07-01

The spatial indexing of eventually all the available topographic information of Earth is a highly valuable tool for different geoscientific application domains. The Shuttle Radar Topography Mission (SRTM) collected and made available to the public one of the world's largest digital elevation models (DEMs). With the aim of providing on easier and faster access to these data by improving their further analysis and processing, we have indexed the SRTM DEM by means of a spatial index based on the kd-tree data structure, called the Q-tree. This paper is the second in a two-part series that includes a thorough performance analysis to validate the bulk-load algorithm efficiency of the Q-tree. We investigate performance measuring elapsed time in different contexts, analyzing disk space usage, testing response time with typical queries, and validating the final index structure balance. In addition, the paper includes performance comparisons with Oracle 11g that helps to understand the real cost of our proposal. Our tests prove that the proposed algorithm outperforms Oracle 11g using around a 9% of the elapsed time, taking six times less storage with more than 96% of page utilization, and getting faster response times to spatial queries issued on 4.5 million points. In addition to this, the behavior of the spatial index has been successfully tested on both an open GIS (VT Builder) and a visualizer tool derived from the previous one.

Effect of coffee and a cola-based soft drink on the color stability of bleached bovine incisors considering the time elapsed after bleaching.

PubMed

Pirolo, Rodrigo; Mondelli, Rafael Francisco Lia; Correr, Gisele Maria; Gonzaga, Carla Castiglia; Furuse, Adilson Yoshio

2014-01-01

There is no consensus about the waiting time necessary for the patient to start consuming beverages containing colorants again after bleaching. To evaluate the influence of beverages with coloring agents on bleached bovine incisors considering the time elapsed after bleaching. Sixty bovine incisors were bleached with 35% hydrogen peroxide for in-office use (Whiteness HP Max) and divided into 10 groups. The color was evaluated with a spectrophotometer (Spectro Shade MICRO) before and after bleaching, employing the CIE-Lab system. After bleaching, the teeth were exposed for 5 min to coffee or cola-based soft drink (CBSD) at different periods after bleaching: 10 min, 1 h, 24 h, 48 h, and 72 h. Color (∆E) and lightness (∆L) variations were obtained from the CIE-Lab coordinates. Data were subjected to two-way ANOVA and Tukey HSD tests (p<0.05). Significant differences were observed between groups for both the ∆L and ∆E values (p<0.001). All specimens presented a decrease in brightness (negative ∆L). The highest ∆E values were observed for teeth stained with a CBSD at 10 min and 1 h (4.12 and 4.16, respectively). Teeth pigmented with coffee presented ∆E values below 3.3 units for all evaluation times. The exposure to coffee after bleaching causes less color changes than the exposure to a CBSD regardless of the time after bleaching.

Multimeric species in equilibrium in detergent-solubilized Na,K-ATPase.

PubMed

Yoneda, Juliana Sakamoto; Scanavachi, Gustavo; Sebinelli, Heitor Gobbi; Borges, Júlio Cesar; Barbosa, Leandro R S; Ciancaglini, Pietro; Itri, Rosangela

2016-08-01

In this work, we find an equilibrium between different Na,K-ATPase (NKA) oligomeric species solubilized in a non-ionic detergent C12E8 by means of Dynamic Light Scattering (DLS), Analytical Ultracentrifugation (AUC), Small Angle X-ray Scattering (SAXS), Spectrophotometry (absorption at 280/350nm) and enzymatic activity assay. The NKA sample after chromatography purification presented seven different populations as identified by AUC, with monomers and tetramers amounting to ∼55% of the total protein mass in solution. These two species constituted less than 40% of the total protein mass after increasing the NKA concentration. Removal of higher-order oligomer/aggregate species from the NKA solution using 220nm-pore filter resulted in an increase of the specific enzymatic activity. Nevertheless, the enzyme forms new large aggregates over an elapsed time of 20h. The results thus point out that C12E8-solubilized NKA is in a dynamic equilibrium of monomers, tetramers and high-order oligomers/subunit aggregates. These latter have low or null activity. High amount of detergent leads to the dissociation of NKA into smaller aggregates with no enzymatic activity. Copyright © 2016. Published by Elsevier B.V.

Continuous time-of-flight ion mass spectrometer

DOEpatents

Funsten, Herbert O.; Feldman, William C.

2004-10-19

A continuous time-of-flight mass spectrometer having an evacuated enclosure with means for generating an electric field located in the evacuated enclosure and means for injecting a sample material into the electric field. A source of continuous ionizing radiation injects ionizing radiation into the electric field to ionize atoms or molecules of the sample material, and timing means determine the time elapsed between arrival of a secondary electron out of said ionized atoms or molecules at a first predetermined location and arrival of a sample ion out of said ionized atoms or molecules at a second predetermined location.

Application of symbolic/numeric matrix solution techniques to the NASTRAN program

NASA Technical Reports Server (NTRS)

Buturla, E. M.; Burroughs, S. H.

1977-01-01

The matrix solving algorithm of any finite element algorithm is extremely important since solution of the matrix equations requires a large amount of elapse time due to null calculations and excessive input/output operations. An alternate method of solving the matrix equations is presented. A symbolic processing step followed by numeric solution yields the solution very rapidly and is especially useful for nonlinear problems.

Lake Nasser on Nile River in Egypt as seen from the Apollo 7 spacecraft

NASA Image and Video Library

1968-10-12

Lake Nasser on the Nile River in southeastern United Arab Republic (Egypt) as seen from the Apollo 7 spacecraft during its 10th revolution of the earth. Photographed from an altitude of 130 nautical miles, at ground elapsed time of 14 hours and 56 minutes. Lake Nasser was created by the contruction of the Aswan Dam on the Nile.

Mountain ranges in western Pakistan as seen from the Apollo 7 spacecraft

NASA Image and Video Library

1968-10-15

AS07-07-1832 (15 Oct. 1968) --- Toba, Kakar, Fort Sandeman, Sulaiman Range area in (West) Pakistan, as seen from the Apollo 7 spacecraft during its 84th revolution of Earth. Note geological features such as folded mountain structures, anticlines and synclines. Photographed from an altitude of 108 nautical miles, at ground elapsed time of 132 hours and 30 minutes.

Improvements of PKU PMECRIS for continuous hundred hours CW proton beam operation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peng, S. X., E-mail: sxpeng@pku.edu.cn; Ren, H. T.; Zhang, T.

2016-02-15

In order to improve the source stability, a long term continuous wave (CW) proton beam experiment has been carried out with Peking University compact permanent magnet 2.45 GHz ECR ion source (PKU PMECRIS). Before such an experiment a lot of improvements and modifications were completed on the source body, the Faraday cup and the PKU ion source test bench. At the beginning of 2015, a continuous operation of PKU PMECRIS for 306 h with more than 50 mA CW beam was carried out after success of many short term tests. No plasma generator failure or high voltage breakdown was observedmore » during that running period and the proton source reliability is near 100%. Total beam availability, which is defined as 35-keV beam-on time divided by elapsed time, was higher than 99% [S. X. Peng et al., Chin. Phys. B 24(7), 075203 (2015)]. A re-inspection was performed after another additional 100 h operation (counting time) and no obvious sign of component failure was observed. Counting the previous source testing time together, this PMECRs longevity is now demonstrated to be greater than 460 h. This paper is mainly concentrated on the improvements for this long term experiment.« less

Workflow efficiency of two 1.5 T MR scanners with and without an automated user interface for head examinations.

PubMed

Moenninghoff, Christoph; Umutlu, Lale; Kloeters, Christian; Ringelstein, Adrian; Ladd, Mark E; Sombetzki, Antje; Lauenstein, Thomas C; Forsting, Michael; Schlamann, Marc

2013-06-01

Workflow efficiency and workload of radiological technologists (RTs) were compared in head examinations performed with two 1.5 T magnetic resonance (MR) scanners equipped with or without an automated user interface called "day optimizing throughput" (Dot) workflow engine. Thirty-four patients with known intracranial pathology were examined with a 1.5 T MR scanner with Dot workflow engine (Siemens MAGNETOM Aera) and with a 1.5 T MR scanner with conventional user interface (Siemens MAGNETOM Avanto) using four standardized examination protocols. The elapsed time for all necessary work steps, which were performed by 11 RTs within the total examination time, was compared for each examination at both MR scanners. The RTs evaluated the user-friendliness of both scanners by a questionnaire. Normality of distribution was checked for all continuous variables by use of the Shapiro-Wilk test. Normally distributed variables were analyzed by Student's paired t-test, otherwise Wilcoxon signed-rank test was used to compare means. Total examination time of MR examinations performed with Dot engine was reduced from 24:53 to 20:01 minutes (P < .001) and the necessary RT intervention decreased by 61% (P < .001). The Dot engine's automated choice of MR protocols was significantly better assessed by the RTs than the conventional user interface (P = .001). According to this preliminary study, the Dot workflow engine is a time-saving user assistance software, which decreases the RTs' effort significantly and may help to automate neuroradiological examinations for a higher workflow efficiency. Copyright © 2013 AUR. Published by Elsevier Inc. All rights reserved.

Long-term cardiovascular risk of nonsteroidal anti-inflammatory drug use according to time passed after first-time myocardial infarction: a nationwide cohort study.

PubMed

Olsen, Anne-Marie Schjerning; Fosbøl, Emil L; Lindhardsen, Jesper; Folke, Fredrik; Charlot, Mette; Selmer, Christian; Bjerring Olesen, Jonas; Lamberts, Morten; Ruwald, Martin H; Køber, Lars; Hansen, Peter R; Torp-Pedersen, Christian; Gislason, Gunnar H

2012-10-16

The cardiovascular risk after the first myocardial infarction (MI) declines rapidly during the first year. We analyzed whether the cardiovascular risk associated with using nonsteroidal anti-inflammatory drugs (NSAIDs) was associated with the time elapsed following first-time MI. We identified patients aged 30 years or older admitted with first-time MI in 1997 to 2009 and subsequent NSAID use by individual-level linkage of nationwide registries of hospitalization and drug dispensing from pharmacies in Denmark. We calculated the incidence rates of death and a composite end point of coronary death or nonfatal recurrent MIs associated with NSAID use in 1-year time intervals up to 5 years after inclusion and analyzed risk by using multivariable adjusted time-dependent Cox proportional hazards models. Of the 99 187 patients included, 43 608 (44%) were prescribed NSAIDs after the index MI. There were 36 747 deaths and 28 693 coronary deaths or nonfatal recurrent MIs during the 5 years of follow-up. Relative to noncurrent treatment with NSAIDs, the use of any NSAID in the years following MI was persistently associated with an increased risk of death (hazard ratio 1.59 [95% confidence interval, 1.49-1.69]) after 1 year and hazard ratio 1.63 [95% confidence interval, 1.52-1.74] after 5 years) and coronary death or nonfatal recurrent MI (hazard ratio, 1.30 [95% confidence interval,l 1.22-1.39] and hazard ratio, 1.41 [95% confidence interval, 1.28-1.55]). The use of NSAIDs is associated with persistently increased coronary risk regardless of time elapsed after first-time MI. We advise long-term caution in the use of NSAIDs for patients after MI.

Vortex generator design for aircraft inlet distortion as a numerical optimization problem

NASA Technical Reports Server (NTRS)

Anderson, Bernhard H.; Levy, Ralph

1991-01-01

Aerodynamic compatibility of aircraft/inlet/engine systems is a difficult design problem for aircraft that must operate in many different flight regimes. Takeoff, subsonic cruise, supersonic cruise, transonic maneuvering, and high altitude loiter each place different constraints on inlet design. Vortex generators, small wing like sections mounted on the inside surfaces of the inlet duct, are used to control flow separation and engine face distortion. The design of vortex generator installations in an inlet is defined as a problem addressable by numerical optimization techniques. A performance parameter is suggested to account for both inlet distortion and total pressure loss at a series of design flight conditions. The resulting optimization problem is difficult since some of the design parameters take on integer values. If numerical procedures could be used to reduce multimillion dollar development test programs to a small set of verification tests, numerical optimization could have a significant impact on both cost and elapsed time to design new aircraft.

Role of the Pineal Body Hormone in Thyroid Function; L'HORMONE EPIPHSAIRE INTERVIENT DANS LA DYNAMIQUE DU METABOLISME DE L'IODE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Milcou, S.M.; Costiner, E. et al.

To evaluate the action of the pineal body hormone on thyroid function, hyperactivity of the epiphysis was experimentally induced by administering pineal body hormone four hours before the experiment and then every four hours during the experiment. Iodine tagging was achieved by the intraperltoneal injection of carrierless'' I/sup 131/. The animals, which had been divided into batches of 10, were sacrificed every 2 hours until 48 hours had elapsed following the radioactive tagging. Measurements on the radioactivity of the thyroid and of the blood were carried out in vitro. The values obtained were used in order to draw up simultaneousmore » radioactivity curves applicable to the total radioactivity and to that attributable to inorganic and organic iodine, respectively. The curves showing the variation in the radioactivity reveal a delayed action of the pineal gland hormone which is different according to whether the functional thyroid units have a large or small time constant. (auth)« less

Correlation between electrical, mechanical and chemical properties of fresh and used aircraft engine oils

NASA Astrophysics Data System (ADS)

Gajewski, Juliusz B.; Głogowski, Marek J.; Paszkowski, Maciej; Czarnik-Matusewicz, Bogusława

2011-06-01

In this paper the results are presented of measurements of electrical, mechanical and chemical properties of fresh and used aircraft engine oils. Oils were used in a four-stroke aircraft engine and their samples were taken after the 50-hour work of the engine. The resistivity, permittivity and viscosity of oils were measured as a function of temperature. Additionally, some measurements of the absorbance spectra and size of particles contained in the oils were carried out. The significant reduction in the resistivity of the used Total oil was observed. The relative permittivity of both used oils was slightly increased. The oil's relative viscosity depends on temperature of oil and given time that elapsed from the very first moment when the shear force was applied in a rheometer. The results obtained allowed one to identify more precisely the chemical and physico-chemical interactions occurring in the tested samples, as compared with a typical infrared spectroscopy.

Temporal trends in arthropod abundances after the transition to organic farming in paddy fields.

PubMed

Tsutsui, Masaru H; Kobayashi, Kazuhiko; Miyashita, Tadashi

2018-01-01

Organic farming aims to reduce the effect on the ecosystem and enhance biodiversity in agricultural areas, but the long-term effectiveness of its application is unclear. Assessments have rarely included various taxonomic groups with different ecological and economic roles. In paddy fields with different numbers of years elapsed since the transition from conventional to organic farming, we investigated changes in the abundance of insect pests, generalist predators, and species of conservation concern. The abundance of various arthropods exhibited diverse trends with respect to years elapsed since the transition to organic farming. Larval lepidopterans, Tetragnatha spiders, and some planthoppers and stink bugs showed non-linear increases over time, eventually reaching saturation, such as the abundance increasing for several years and then becoming stable after 10 years. This pattern can be explained by the effects of residual pesticides, the lag time of soil mineralization, and dispersal limitation. A damselfly (Ischnura asiatica) did not show a particular trend over time, probably due to its rapid immigration from source habitats. Unexpectedly, both planthoppers and some leafhoppers exhibited gradual decreases over time. As their abundances were negatively related to the abundance of Tetragnatha spiders, increased predation by natural enemies might gradually decrease these insect populations. These results suggest that the consideration of time-dependent responses of organisms is essential for the evaluation of the costs and benefits of organic farming, and such evaluations could provide a basis for guidelines regarding the length of time for organic farming to restore biodiversity or the economic subsidy needed to compensate for pest damage.

Temporal trends in arthropod abundances after the transition to organic farming in paddy fields

PubMed Central

Tsutsui, Masaru H.; Kobayashi, Kazuhiko

2018-01-01

Organic farming aims to reduce the effect on the ecosystem and enhance biodiversity in agricultural areas, but the long-term effectiveness of its application is unclear. Assessments have rarely included various taxonomic groups with different ecological and economic roles. In paddy fields with different numbers of years elapsed since the transition from conventional to organic farming, we investigated changes in the abundance of insect pests, generalist predators, and species of conservation concern. The abundance of various arthropods exhibited diverse trends with respect to years elapsed since the transition to organic farming. Larval lepidopterans, Tetragnatha spiders, and some planthoppers and stink bugs showed non-linear increases over time, eventually reaching saturation, such as the abundance increasing for several years and then becoming stable after 10 years. This pattern can be explained by the effects of residual pesticides, the lag time of soil mineralization, and dispersal limitation. A damselfly (Ischnura asiatica) did not show a particular trend over time, probably due to its rapid immigration from source habitats. Unexpectedly, both planthoppers and some leafhoppers exhibited gradual decreases over time. As their abundances were negatively related to the abundance of Tetragnatha spiders, increased predation by natural enemies might gradually decrease these insect populations. These results suggest that the consideration of time-dependent responses of organisms is essential for the evaluation of the costs and benefits of organic farming, and such evaluations could provide a basis for guidelines regarding the length of time for organic farming to restore biodiversity or the economic subsidy needed to compensate for pest damage. PMID:29324809

Inner Plasma Structure of the Low-Latitude Reconnection Layer

NASA Technical Reports Server (NTRS)

Zhang, Q.-H.; Dunlop, M. W.; Lockwood, M.; Lavraud, B.; Bogdanova, Y. V.; Hasegawa, H.; Yang, H. -G.; Liu, R. -Y.; Hu, H. -Q.; Zhang, B. -C.;

The Levels of Cortisol, Oxidative Stress, and DNA Damage in the Victims of Childhood Sexual Abuse: A Preliminary Study.

PubMed

Şimşek, Şeref; Kaplan, İbrahim; Uysal, Cem; Yüksel, Tuğba; Alaca, Rümeysa

2016-01-01

In this study we aimed to investigate serum cortisol, oxidative stress, and DNA damage in children who are sexual abuse victims. The study included 38 children who sustained child sexual abuse and 38 age- and gender-matched children who did not have a history of trauma. Cortisol levels reflecting the status of the hypothalamic-pituitary-adrenal axis, anti-oxidant enzymes glutathione peroxidase, superoxide dismutase, natural anti-oxidant coenzyme Q, and 8-hydroxy-2-deoxyguanosine as the indicator of DNA damage were analyzed in serum samples using the enzyme linked immunosorbent assay method. Cortisol levels were significantly higher in the child sexual abuse group compared to the control group. There were no significant differences between the groups in terms of oxidative stress and DNA damage. Cortisol and 8-hydroxy-2-deoxyguanosine levels decreased as the time elapsed since the sexual abuse increased. Coenzyme Q level was lower in victims who sustained multiple assaults than in the victims of a single assault. Cortisol and superoxide dismutase levels were lower in the victims of familial sexual abuse. Decreases in cortisol and 8-hydroxy-2-deoxyguanosine levels as time elapsed may be an adaptation to the toxic effects of high cortisol levels over a prolonged period of time. Child sexual abuse did not result in oxidative stress and DNA damage; however, some features of sexual abuse raised the level of oxidative stress.

A chemical rationalization of the processing and application of the mortar coatings: Structural, thermodynamic, and fluorescence properties

NASA Astrophysics Data System (ADS)

Lima, Nathan B.; Rogerio, V. A.; Belarmino, Marcia K. D. L.; Silva, Anderson I. S.; Ioras, Renan U. F.; Oliveira, Romilde A.; Lima, Nathalia B. D.

2018-07-01

A chemical rationalization of the processing and application of the roughcast and plaster mortar coatings was advanced. The results revealed that the structural and thermodynamic nature of the hydrogen-bonded complexes between the inorganic precursors and water molecules are associated with the physical properties of both coatings. In this sense, the workability and curing time of the roughcast and the plaster mortars studied, seemingly, are related to the nature of the water solvation in the main components of these materials: calcium hydroxide and silicon dioxide. In addition, PM7 and PM7/COSMO results indicate that the enthalpy of solvation of water by hydrogen bonds in calcium hydroxide is stronger when compared with silicon dioxide systems. Therefore, the presence of free hydrated lime (calcium hydroxide) in the precursor mixture of plaster mortar leads to the large workability and elapsed curing time of this material. On the other hand, the absence of free hydrated lime in the precursor mixture of the roughcast mortar leads to its poor workability and faster elapsed curing time. Further, fluorescence microscopy experiments revealed that the inorganic compounds present in the cement precursor were transformed into different materials, that exhibit red and blue fluorescence. Finally, mechanical tests showed a tensile strength average 0.67 MPa for the plaster mortar material, whereas for the roughcast material is 0.53 MPa.

Measurement of rheologic property of blood by a falling-ball blood viscometer.

PubMed

Eguchi, Yoko; Karino, Takeshi

2008-04-01

The viscosity of blood obtained by using a rotational viscometer decreases with the time elapsed from the beginning of measurement until it reaches a constant value determined by the magnitude of shear rate. It is not possible to obtain an initial value of viscosity at time t = 0 that is considered to exhibit an intrinsic property of the fluid by this method. Therefore, we devised a new method by which one can obtain the viscosity of various fluids that are not affected by both the time elapsed from the beginning of measurement and the magnitude of shear rate by considering the balance of the forces acting on a solid spherical particle freely falling in a quiescent viscous fluid. By using the new method, we studied the rheologic behavior of corn syrups, carboxy-methyl cellulose, and human blood; and compared the results with those obtained with a cone-and-plate viscometer. It was found that in the case of corn syrups and washed red cell suspensions in which no red cell aggregate (rouleau) was formed, the viscosity obtained with the two different methods were almost the same. In contrast to this, in the case of the whole blood in which massive aggregates were formed, the viscosity obtained with a falling-ball viscometer was much larger than that obtained with a cone-plate viscometer.

On the statistics of El Nino occurrences and the relationship of El Nino to volcanic and solar/geomagnetic activity

NASA Technical Reports Server (NTRS)

Wilson, Robert M.

1989-01-01

El Nino is conventionally defined as an anomalous and persistent warming of the waters off the coasts of Ecuador and Peru in the eastern equatorial Pacific, having onset usually in Southern Hemispheric summer/fall. Some of the statistical aspects of El Nino occurrences are examined, especially as they relate to the normal distribution and to possible associations with volcanic, solar, and geomagnetic activity. With regard to the very strong El Nino of 1982 to 1983, it is noted that, although it may very well be related to the 1982 eruptions of El Chichon, the event occurred essentially on time (with respect to the past behavior of elapsed times between successive El Nino events; a moderate-to-stronger El Nino was expected during the interval 1978 to 1982, assuming that El Nino occurrences are normally distributed, having a mean elapsed time between successive onsets of 4 years and a standard deviation of 2 years and a last known occurrence in 1976). Also, although not widely recognized, the whole of 1982 was a record year for geomagnetic activity (based on the aa geomagnetic index, with the aa index registering an all time high in February 1982), perhaps, important for determining a possible trigger for this and other El Nino events. A major feature is an extensive bibliography (325 entries) on El Nino and volcanic-solar-geomagnetic effects on climate. Also, included is a tabular listing of the 94 major volcanic eruptions of 1835 to 1986.

Relativistic time transfer in the vicinity of the Earth and in the solar system

NASA Astrophysics Data System (ADS)

Nelson, Robert A.

2011-08-01

The algorithms for relativistic time transfer in the vicinity of the Earth and in the solar system are derived. The concepts of proper time and coordinate time are distinguished. The coordinate time elapsed during the transport of a clock and the propagation of an electromagnetic signal is analysed in three coordinate systems: an Earth-Centred Inertial (ECI) coordinate system, an Earth-Centred Earth-Fixed (ECEF) coordinate system and a barycentric coordinate system. The timescales of Geocentric Coordinate Time (TCG), Terrestrial Time (TT) and Barycentric Coordinate Time (TCB) are defined and their relationships are discussed. Some numerical examples are provided to illustrate the magnitudes of the effects.

Adrenal Hormones in Common Bottlenose Dolphins (Tursiops truncatus): Influential Factors and Reference Intervals.

PubMed

Hart, Leslie B; Wells, Randall S; Kellar, Nick; Balmer, Brian C; Hohn, Aleta A; Lamb, Stephen V; Rowles, Teri; Zolman, Eric S; Schwacke, Lori H

2015-01-01

Inshore common bottlenose dolphins (Tursiops truncatus) are exposed to a broad spectrum of natural and anthropogenic stressors. In response to these stressors, the mammalian adrenal gland releases hormones such as cortisol and aldosterone to maintain physiological and biochemical homeostasis. Consequently, adrenal gland dysfunction results in disruption of hormone secretion and an inappropriate stress response. Our objective herein was to develop diagnostic reference intervals (RIs) for adrenal hormones commonly associated with the stress response (i.e., cortisol, aldosterone) that account for the influence of intrinsic (e.g., age, sex) and extrinsic (e.g., time) factors. Ultimately, these reference intervals will be used to gauge an individual's response to chase-capture stress and could indicate adrenal abnormalities. Linear mixed models (LMMs) were used to evaluate demographic and sampling factors contributing to differences in serum cortisol and aldosterone concentrations among bottlenose dolphins sampled in Sarasota Bay, Florida, USA (2000-2012). Serum cortisol concentrations were significantly associated with elapsed time from initial stimulation to sample collection (p<0.05), and RIs were constructed using nonparametric methods based on elapsed sampling time for dolphins sampled in less than 30 minutes following net deployment (95% RI: 0.91-4.21 µg/dL) and following biological sampling aboard a research vessel (95% RI: 2.32-6.68 µg/dL). To examine the applicability of the pre-sampling cortisol RI across multiple estuarine stocks, data from three additional southeast U.S. sites were compared, revealing that all of the dolphins sampled from the other sites (N = 34) had cortisol concentrations within the 95th percentile RI. Significant associations between serum concentrations of aldosterone and variables reported in previous studies (i.e., age, elapsed sampling time) were not observed in the current project (p<0.05). Also, approximately 16% of Sarasota Bay bottlenose dolphin aldosterone concentrations were below the assay's detection limit (11 pg/mL), thus hindering the ability to derive 95th percentile RIs. Serum aldosterone concentrations from animals sampled at the three additional sites were compared to the detection limit, and the proportion of animals with low aldosterone concentrations was not significantly different than an expected prevalence of 16%. Although this study relied upon long-term, free-ranging bottlenose dolphin health data from a single site, the objective RIs can be used for future evaluation of adrenal function among individuals sampled during capture-release health assessments.

Pole blight - a new disease of western white pine

Treesearch

C. A. Wellner

1947-01-01

Pole blight is a killer. Apparently attacking pole-size western white pine trees of any vigor or crown class, it seems to require from one to ten years to kill a tree. White pine is generally believed to be the only species susceptible, although there is a possibility that grand fir and Douglas-fir also may be attacked. Not enough time has elapsed for us to say how...

Fifth Graders' Additive and Multiplicative Reasoning: Establishing Connections across Conceptual Fields Using a Graph

ERIC Educational Resources Information Center

Caddle, Mary C.; Brizuela, Barbara M.

2011-01-01

This paper looks at 21 fifth grade students as they discuss a linear graph in the Cartesian plane. The problem presented to students depicted a graph showing distance as a function of elapsed time for a person walking at a constant rate of 5 miles/h. The question asked students to consider how many more hours, after having already walked 4 h,…

40 CFR Figure E-1 to Subpart E of... - Designation Testing Checklist

Code of Federal Regulations, 2014 CFR

2014-07-01

... coefficient of variation (§ 53.53) (L-7.4.3) Filter temperature control (sampling) (§ 53.57) (L-7.4.10) Elapsed sample time accuracy (§ 53.54) (L-7.4.13) Filter temperature control (post sampling) (§ 53.57) (L... requirements (part 53, subpart A, § 53.2(a)(3)) (part 53, subpart E, § 53.51(a),(d)) Filter Weighing (L-8...

40 CFR Figure E-1 to Subpart E of... - Designation Testing Checklist

Code of Federal Regulations, 2011 CFR

2011-07-01

... coefficient of variation (§ 53.53) (L-7.4.3) Filter temperature control (sampling) (§ 53.57) (L-7.4.10) Elapsed sample time accuracy (§ 53.54) (L-7.4.13) Filter temperature control (post sampling) (§ 53.57) (L... requirements (part 53, subpart A, § 53.2(a)(3)) (part 53, subpart E, § 53.51(a),(d)) Filter Weighing (L-8...

The International Conference on Vector and Parallel Computing (2nd)

DTIC Science & Technology

1989-01-17

Computation of the SVD of Bidiagonal Matrices" ...................................... 11 " Lattice QCD -As a Large Scale Scientific Computation...vectorizcd for the IBM 3090 Vector Facility. In addition, elapsed times " Lattice QCD -As a Large Scale Scientific have been reduced by using 3090...benchmarked Lattice QCD on a large number ofcompu- come from the wavefront solver routine. This was exten- ters: CrayX-MP and Cray 2 (vector

JPRS Report, West Europe.

DTIC Science & Technology

1988-02-03

hint interestingly at current moods, especially if the data are combined with other surveys conducted by Economy Research, Inc., for UUSI SUOMI in...likewise a problem, especially if a long time has elapsed since the previous election. Comparison is also made difficult by different-sized samples... especially , for worse; all of them are awaiting their chance. And that fact—that is, the existence of a majority composed of men who are constantly

Demonstration of the efficiency and robustness of an acid leaching process to remove metals from various CCA-treated wood samples.

PubMed

Coudert, Lucie; Blais, Jean-François; Mercier, Guy; Cooper, Paul; Janin, Amélie; Gastonguay, Louis

2014-01-01

In recent years, an efficient and economically attractive leaching process has been developed to remove metals from copper-based treated wood wastes. This study explored the applicability of this leaching process using chromated copper arsenate (CCA) treated wood samples with different initial metal loading and elapsed time between wood preservation treatment and remediation. The sulfuric acid leaching process resulted in the solubilization of more than 87% of the As, 70% of the Cr, and 76% of the Cu from CCA-chips and in the solubilization of more than 96% of the As, 78% of the Cr and 91% of the Cu from CCA-sawdust. The results showed that the performance of this leaching process might be influenced by the initial metal loading of the treated wood wastes and the elapsed time between preservation treatment and remediation. The effluents generated during the leaching steps were treated by precipitation-coagulation to satisfy the regulations for effluent discharge in municipal sewers. Precipitation using ferric chloride and sodium hydroxide was highly efficient, removing more than 99% of the As, Cr, and Cu. It appears that this leaching process can be successfully applied to remove metals from different CCA-treated wood samples and then from the effluents. Copyright © 2013 Elsevier Ltd. All rights reserved.

Primary Hyperparathyroidism in Older People: Surgical Treatment with Minimally Invasive Approaches and Outcome

PubMed Central

Dobrinja, Chiara; Silvestri, Marta; de Manzini, Nicolò

2012-01-01

Introduction. Elderly patients with primary hyperparathyroidism (pHPT) are often not referred to surgery because of their associated comorbidities that may increase surgical risk. The aim of the study was to review indications and results of minimally invasive approach parathyroidectomy in elderly patients to evaluate its impact on outcome. Materials and Methods. All patients of 70 years of age or older undergoing minimally approach parathyroidectomy at our Department from May 2005 to May 2011 were reviewed. Data collected included patients demographic information, biochemical pathology, time elapsed from pHPT diagnosis to surgical intervention, operative findings, complications, and results of postoperative biochemical studies. Results and Discussion. 37 patients were analysed. The average length of stay was 2.8 days. 11 patients were discharged within 24 hours after their operation. Morbidity included 6 transient symptomatic postoperative hypocalcemias while one patient developed a transient laryngeal nerve palsy. Time elapsed from pHPT diagnosis to first surgical visit evidences that the elderly patients were referred after their disease had progressed. Conclusions. Our data show that minimally invasive approach to parathyroid surgery seems to be safe and curative also in elderly patients with few associated risks because of combination of modern preoperative imaging, advances in surgical technique, and advances in anesthesia care. PMID:22737167

Effects of diet-deprivation and physical stimulation on the feeding behaviour of the larvae of the silkworm, Bombyx mori.

PubMed

Nagata, Shinji; Nagasawa, Hiromichi

2006-08-01

Continuous observations of larvae of the silkworm, Bombyx mori, revealed that feeding occurred at regular intervals throughout larval development. To investigate possible factors influencing meal-timing, the behaviours of diet-deprived Bombyx larvae were also analysed. Diet-deprivation resulted in longer durations of the first meals after diet replacement, but did not affect feeding patterns. Furthermore, long-term diet-deprivation promoted wandering behaviour and a consequent delay in feeding after diet replacement. Under diet-deprivation conditions, meal-starts appeared to be inducible by defecation and physical stimulation. However, stimulation-induced meal-starts were dependent on the time elapsed since the larvae's previous meals. Provided that more than 1h had elapsed since their previous meals, larvae could be induced to feed by defecation and tapping. At less than 1h post-meal, larvae were less likely to begin feeding after defecation or physical stimulation. Activated locomotions such as wandering and feeding were observed in the long-term diet-deprived larvae only after diet blocks were replaced, while long-term diet-deprived larvae did not show activated locomotion during the absence of diet blocks. Collectively, these data suggest that a combination of elevated locomotion activity and the presence of diet may be necessary for the initiation of feeding in diet-deprived larvae.

GPU-accelerated compressed-sensing (CS) image reconstruction in chest digital tomosynthesis (CDT) using CUDA programming

NASA Astrophysics Data System (ADS)

Choi, Sunghoon; Lee, Haenghwa; Lee, Donghoon; Choi, Seungyeon; Shin, Jungwook; Jang, Woojin; Seo, Chang-Woo; Kim, Hee-Joung

2017-03-01

A compressed-sensing (CS) technique has been rapidly applied in medical imaging field for retrieving volumetric data from highly under-sampled projections. Among many variant forms, CS technique based on a total-variation (TV) regularization strategy shows fairly reasonable results in cone-beam geometry. In this study, we implemented the TV-based CS image reconstruction strategy in our prototype chest digital tomosynthesis (CDT) R/F system. Due to the iterative nature of time consuming processes in solving a cost function, we took advantage of parallel computing using graphics processing units (GPU) by the compute unified device architecture (CUDA) programming to accelerate our algorithm. In order to compare the algorithmic performance of our proposed CS algorithm, conventional filtered back-projection (FBP) and simultaneous algebraic reconstruction technique (SART) reconstruction schemes were also studied. The results indicated that the CS produced better contrast-to-noise ratios (CNRs) in the physical phantom images (Teflon region-of-interest) by factors of 3.91 and 1.93 than FBP and SART images, respectively. The resulted human chest phantom images including lung nodules with different diameters also showed better visual appearance in the CS images. Our proposed GPU-accelerated CS reconstruction scheme could produce volumetric data up to 80 times than CPU programming. Total elapsed time for producing 50 coronal planes with 1024×1024 image matrix using 41 projection views were 216.74 seconds for proposed CS algorithms on our GPU programming, which could match the clinically feasible time ( 3 min). Consequently, our results demonstrated that the proposed CS method showed a potential of additional dose reduction in digital tomosynthesis with reasonable image quality in a fast time.

Effect of coffe and a cola-based soft drink on the color stability of bleached bovine incisors considering the time elapsed after bleaching

PubMed Central

PIROLO, Rodrigo; MONDELLI, Rafael Francisco Lia; CORRER, Gisele Maria; GONZAGA, Carla Castiglia; FURUSE, Adilson Yoshio

2014-01-01

There is no consensus about the waiting time necessary for the patient to start consuming beverages containing colorants again after bleaching. Objective: To evaluate the influence of beverages with coloring agents on bleached bovine incisors considering the time elapsed after bleaching. Materials and methods: Sixty bovine incisors were bleached with 35% hydrogen peroxide for in-office use (Whiteness HP Max) and divided into 10 groups. The color was evaluated with a spectrophotometer (Spectro Shade MICRO) before and after bleaching, employing the CIE-Lab system. After bleaching, the teeth were exposed for 5 min to coffee or cola-based soft drink (CBSD) at different periods after bleaching: 10 min, 1 h, 24 h, 48 h, and 72 h. Color (∆E) and lightness (∆L) variations were obtained from the CIE-Lab coordinates. Data were subjected to two-way ANOVA and Tukey HSD tests (p<0.05). Results: Significant differences were observed between groups for both the ∆L and ∆E values (p<0.001). All specimens presented a decrease in brightness (negative ∆L). The highest ∆E values were observed for teeth stained with a CBSD at 10 min and 1 h (4.12 and 4.16, respectively). Teeth pigmented with coffee presented ∆E values below 3.3 units for all evaluation times. Conclusion: The exposure to coffee after bleaching causes less color changes than the exposure to a CBSD regardless of the time after bleaching. PMID:25075672

Time-elapsed screw insertion with microCT imaging.

PubMed

Ryan, M K; Mohtar, A A; Cleek, T M; Reynolds, K J

2016-01-25

Time-elapsed analysis of bone is an innovative technique that uses sequential image data to analyze bone mechanics under a given loading regime. This paper presents the development of a novel device capable of performing step-wise screw insertion into excised bone specimens, within the microCT environment, whilst simultaneously recording insertion torque, compression under the screw head and rotation angle. The system is computer controlled and screw insertion is performed in incremental steps of insertion torque. A series of screw insertion tests to failure were performed (n=21) to establish a relationship between the torque at head contact and stripping torque (R(2)=0.89). The test-device was then used to perform step-wise screw insertion, stopping at intervals of 20%, 40%, 60% and 80% between screw head contact and screw stripping. Image data-sets were acquired at each of these time-points as well as at head contact and post-failure. Examination of the image data revealed the trabecular deformation as a result of increased insertion torque was restricted to within 1mm of the outer diameter of the screw thread. Minimal deformation occurred prior to the step between the 80% time-point and post-failure. The device presented has allowed, for the first time, visualization of the micro-mechanical response in the peri-implant bone with increased tightening torque. Further testing on more samples is expected to increase our understanding of the effects of increased tightening torque at the micro-structural level, and the failure mechanisms of trabeculae. Copyright © 2015 Elsevier Ltd. All rights reserved.

Fourth-grade children's dietary recall accuracy is influenced by retention interval (target period and interview time).

PubMed

Baxter, Suzanne Domel; Hardin, James W; Guinn, Caroline H; Royer, Julie A; Mackelprang, Alyssa J; Smith, Albert F

2009-05-01

For a 24-hour dietary recall, two possible target periods are the prior 24 hours (24 hours immediately preceding the interview time) and previous day (midnight to midnight of the day before the interview), and three possible interview times are morning, afternoon, and evening. Target period and interview time determine the retention interval (elapsed time between to-be-reported meals and the interview), which, along with intervening meals, can influence reporting accuracy. The effects of target period and interview time on children's accuracy for reporting school meals during 24-hour dietary recalls were investigated. DESIGN AND SUBJECTS/SETTING: During the 2004-2005, 2005-2006, and 2006-2007 school years in Columbia, SC, each of 374 randomly selected fourth-grade children (96% African American) was observed eating two consecutive school meals (breakfast and lunch) and interviewed to obtain a 24-hour dietary recall using one of six conditions defined by crossing two target periods with three interview times. Each condition had 62 or 64 children (half boys). Accuracy for reporting school meals was quantified by calculating rates for omissions (food items observed eaten but unreported) and intrusions (food items reported eaten but unobserved); a measure of total inaccuracy combined errors for reporting food items and amounts. For each accuracy measure, analysis of variance was conducted with target period, interview time, their interaction, sex, interviewer, and school year in the model. There was a target-period effect and a target-period by interview-time interaction on omission rates, intrusion rates, and total inaccuracy (six P values <0.004). For prior-24-hour recalls compared to previous-day recalls, and for prior-24-hour recalls in the afternoon and evening compared to previous-day recalls in the afternoon and evening, omission rates were better by one third, intrusion rates were better by one half, and total inaccuracy was better by one third. To enhance children's dietary recall accuracy, target periods and interview times that minimize the retention interval should be chosen.

Time-Temperature Indicator Based on Enzymatic Degradation of Dye-Loaded Polyhydroxybutyrate.

PubMed

Anbukarasu, Preetam; Sauvageau, Dominic; Elias, Anastasia L

2017-09-01

An enzyme activated time-temperature indicator (TTI) which produces a direct colour change concomitant to variations in integrated time and temperature conditions is described. This direct colour change is realised by degrading a dye-loaded polyhydroxybutyrate (PHB) film by a depolymerase enzyme. The degradation of the PHB film by the enzyme causes the release of the dye in solution, which in turn undergoes an optical transition from clear to coloured with elapsing time. Macroscopic and microscopic optical observations confirms the uniform distribution of the dye in the PHB film. The dye release kinetics, mediated by the enzymatic reaction, are tested at different temperatures ranging from 4 to 37 °C, and are used to determine the suitability of a dye-loaded PHB as a time-temperature indicator for fresh food products based on kinetic parameters previously reported. The kinetic analysis shows that the activation energy of the dye release process is 74 kJ mol -1 , and that, at 37 °C, the dye would be totally released within 6 h. However, when incubated at 4 °C, the TTI requires in the range of 168 h (7 days) to release all the dye. These kinetics values highlight the potential of the TTI for monitoring fresh food products that have optimum shelf life around 4 °C. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Stroke treatment outcomes in hospitals with and without Stroke Units.

PubMed

Masjuan, J; Gállego Culleré, J; Ignacio García, E; Mira Solves, J J; Ollero Ortiz, A; Vidal de Francisco, D; López-Mesonero, L; Bestué, M; Albertí, O; Acebrón, F; Navarro Soler, I M

2017-10-23

Organisational capacity in terms of resources and care circuits to shorten response times in new stroke cases is key to obtaining positive outcomes. This study compares therapeutic approaches and treatment outcomes between traditional care centres (with stroke teams and no stroke unit) and centres with stroke units. We conducted a prospective, quasi-experimental study (without randomisation of the units analysed) to draw comparisons between 2 centres with stroke units and 4 centres providing traditional care through the neurology department, analysing a selection of agreed indicators for monitoring quality of stroke care. A total of 225 patients participated in the study. In addition, self-administered questionnaires were used to collect patients' evaluations of the service and healthcare received. Centres with stroke units showed shorter response times after symptom onset, both in the time taken to arrive at the centre and in the time elapsed from patient's arrival at the hospital to diagnostic imaging. Hospitals with stroke units had greater capacity to respond through the application of intravenous thrombolysis than centres delivering traditional neurological care. Centres with stroke units showed a better fit to the reference standards for stroke response time, as calculated in the Quick study, than centres providing traditional care through the neurology department. Copyright © 2017 Sociedad Española de Neurología. Publicado por Elsevier España, S.L.U. All rights reserved.

KSC-06pd1582

NASA Image and Video Library

2006-07-17

KENNEDY SPACE CENTER, FLA. - During the traditional post-flight walk-around after the landing of an orbiter, Mission Specialist Lisa Nowak gets a close look at the nose cone. Discovery's smooth and perfect landing was on time at 9:14 a.m. EDT on Runway 15 of NASA's Shuttle Landing Facility after traveling 5.3 million miles on 202 orbits. Mission elapsed time was 12 days, 18 hours, 37 minutes and 54 seconds. The landing is the 62nd at Kennedy Space Center and the 32nd for Discovery. Photo credit: NASA/Kim Shiflett

KSC-06pd1588

NASA Image and Video Library

2006-07-17

KENNEDY SPACE CENTER, FLA. - Workers and media at NASA's Kennedy Space Center watch while the orbiter Discovery, following the landing from mission STS-121, is prepared for the roll to the Orbiter Processing Facility. Discovery's smooth and perfect landing was on time at 9:14 a.m. EDT on Runway 15 of NASA's Shuttle Landing Facility after traveling 5.3 million miles on 202 orbits. Mission elapsed time was 12 days, 18 hours, 37 minutes and 54 seconds. The landing is the 62nd at Kennedy Space Center and the 32nd for Discovery. Photo credit: NASA/Kim Shiflett

[Comparative study of the conventional scheme and prolonged treatment with steroids on primary steroid-sensitive nephrotic syndrome in children].

PubMed

Liern, Miguel; Codianni, Paola; Vallejo, Graciela

In the steroid-sensitive nephrotic syndrome (SSNS) the prolonged treatment with steroids could decrease the frequency of relapses. We conducted a comparative study of prolonged steroid scheme and the usual treatment of primary SSNS to assess: the number of patients with relapses, mean time to treatment initiation, to remission and to first relapse, total number of relapses, total cumulative dose of steroids, and the steroid toxicity. Patients were divided into two groups: group A (27 patients) received 16-β-methylprednisolone for 12 weeks, reducing the steroid until week 24. Group B (29 patients) received 16-β-methylprednisolone for 12 weeks and placebo until week 24. Cumulative incidence rate of relapse (person/years) for group A was of 36/100 and 66/100 for group B (p=0.04). Average elapsed time to first relapse was of 114 days for group A and of 75 days to for group B (p=0.01). The difference in time for initial response to treatment and up to achieve remission between both groups was not significant. Total cumulative relapses were 9 for group A and 17 for group B (p=0.04). Total patients with relapses were 3 for group A and 7 for group B (p=0.17). Cumulative average dose per patient was 5,243mg/m 2 for group A and 4,306mg/m 2 for group B (p=0.3), and serum cortisol was 14μg/dl for group A and 16μg/dl for group B (p=0.4). There were no steroid toxicity differences between groups. The duration of the treatment had an impact on the number of relapses without increasing steroid toxicity. Copyright © 2016 Hospital Infantil de México Federico Gómez. Publicado por Masson Doyma México S.A. All rights reserved.

Turbulence investigation and reproduction for assisting downstream migrating juvenile salmonids, Part II of II: Effects of induced turbulence on behavior of juvenile salmon, 2001-2005 final report

USGS Publications Warehouse

Perry, R.; Farley , M.; Hansen, G.; Morse , J.; Rondorf, D.

2005-01-01

Passage through dams is a major source of mortality of anadromous juvenile salmonids because some populations must negotiate up to eight dams in Columbia and Snake rivers. Dams cause direct mortality when fish pass through turbines, but dams may also cause indirect mortality by altering migration conditions in rivers. Forebays immediately upstream of dams have decreased the water velocity of rivers and may contribute substantially to the total migration delay of juvenile salmonids. Recently, Coutant (2001a) suggested that in addition to low water velocities, lack of natural turbulence may contribute to migration delay by causing fish to lose directional cues. Coutant (2001a) further hypothesized that restoring turbulence in dam forebays may reduce migration delay by providing directional cues that allow fish to find passage routes more quickly (Coutant 2001a). Although field experiments have yielded proof of the concept of using induced turbulence to guide fish to safe passage routes, little is known about mechanisms actually causing behavioral changes. To test hypotheses about how turbulence influences movement and behavior of migrating juvenile salmonids, we conducted two types of controlled experiments at Cowlitz Falls Dam, Washington. A common measure of migration delay is the elapsed time between arrival at, and passage through, a dam. Therefore, for the first set of experiments, we tested the effect of induced turbulence on the elapsed time needed for fish to traverse through a raceway and pass over a weir at its downstream end (time trial experiment). If turbulence helps guide fish to passage routes, then fish should pass through the raceway quicker in the presence of appropriately scaled and directed turbulent cues. Second, little is known about how the physical properties of water movement provide directional cues to migrating juvenile salmonids. To examine the feasibility of guiding fish with turbulence, we tested whether directed turbulence could guide fish into one of two channels in the raceway, and subsequently cause them to pass disproportionately over the weir where turbulent cues were aimed (guidance experiment). Last, we measured and mapped water velocity and turbulence during the experiments to understand water movement patterns and the spatial distribution of turbulence in the raceways.

Delay to orthopedic consultation for isolated limb injury

PubMed Central

Rouleau, Dominique M.; Feldman, Debbie Ehrmann; Parent, Stefan

2009-01-01

ABSTRACT OBJECTIVE To describe referral mechanisms for referral to orthopedic surgery for isolated limb injuries in a public health care system and to identify factors affecting access. DESIGN Cross-sectional survey. SETTING Orthopedic surgery service in a level 1 trauma centre in Montreal, Que. PARTICIPANTS We conducted a prospective study of 166 consecutive adults (mean age 48 years) referred to orthopedic surgery for isolated limb injuries during a 4-month period. MAIN OUTCOME MEASURES Self-reported data on the nature of the trauma, the elapsed time between injury and orthopedic consultation, the number and type of previous primary care consultations, sociodemographic characteristics, and the level of satisfaction with care. RESULTS Average time between the injury and orthopedic consultation was 89 hours (range 3 to 642), with an average of 68 hours (range 0 to 642) for delay between primary care consultation and orthopedic consultation. A total of 36% of patients with time-sensitive diagnoses had unacceptable delays to orthopedic consultation according to the Quebec Orthopaedic Association guidelines. Lower limb injury, consulting first at another hospital, living far from the trauma centre, patient perception of low severity, and having a soft tissue injury were associated with longer delays. CONCLUSION Identifying gaps and risk factors for slower access might help improve referral mechanisms for orthopedic consultation. PMID:19826162

Crashworthiness characteristics of a carbon fiber reinforced dual-phase epoxy–polyurea hybrid matrix composite

DOE PAGES

Zhou, Hongyu; Attard, Thomas L.; Dhiradhamvit, Kittinan; ...

2014-11-07

In this paper, the crashworthiness characteristics of rectangular tubes made from a Carbon-fiber reinforced Hybrid-Polymeric Matrix (CHMC) composite were investigated using quasi-static and impact crush tests. The hybrid matrix formulation of the CHMC was created by combining an epoxy-based thermosetting polymer with a lightly crosslinked polyurea elastomer at various cure-time intervals and volumetric ratios. The load–displacement responses of both CHMC and carbon-fiber reinforced epoxy (CF/epoxy) specimens were obtained under various crushing speeds; and crashworthiness parameters, such as the average crushing force and specific energy absorption (SEA), were calculated using subsequent load–displacement relationships. The CHMC maintained a high level of structuralmore » integrity and post-crush performance, relative to traditional CF/epoxy. The influence of the curing time and volumetric ratios of the polyurea/epoxy dual-hybridized matrix system on the crashworthiness parameters was also investigated. The results reveal that the load carrying capacity and total energy absorption tend to increase with greater polyurea thickness and lower elapsed reaction curing time of the epoxy although this is typically a function of the loading rate. In conclusion, the mechanism by which the CHMC provides increased damage tolerance was also investigated using scanning electron microscopy (SEM).« less

Comparative analysis of different weight matrices in subspace system identification for structural health monitoring

NASA Astrophysics Data System (ADS)

Shokravi, H.; Bakhary, NH

2017-11-01

Subspace System Identification (SSI) is considered as one of the most reliable tools for identification of system parameters. Performance of a SSI scheme is considerably affected by the structure of the associated identification algorithm. Weight matrix is a variable in SSI that is used to reduce the dimensionality of the state-space equation. Generally one of the weight matrices of Principle Component (PC), Unweighted Principle Component (UPC) and Canonical Variate Analysis (CVA) are used in the structure of a SSI algorithm. An increasing number of studies in the field of structural health monitoring are using SSI for damage identification. However, studies that evaluate the performance of the weight matrices particularly in association with accuracy, noise resistance, and time complexity properties are very limited. In this study, the accuracy, noise-robustness, and time-efficiency of the weight matrices are compared using different qualitative and quantitative metrics. Three evaluation metrics of pole analysis, fit values and elapsed time are used in the assessment process. A numerical model of a mass-spring-dashpot and operational data is used in this research paper. It is observed that the principal components obtained using PC algorithms are more robust against noise uncertainty and give more stable results for the pole distribution. Furthermore, higher estimation accuracy is achieved using UPC algorithm. CVA had the worst performance for pole analysis and time efficiency analysis. The superior performance of the UPC algorithm in the elapsed time is attributed to using unit weight matrices. The obtained results demonstrated that the process of reducing dimensionality in CVA and PC has not enhanced the time efficiency but yield an improved modal identification in PC.

Prognosis and Conditional Disease-Free Survival Among Patients With Ovarian Cancer

PubMed Central

Kurta, Michelle L.; Edwards, Robert P.; Moysich, Kirsten B.; McDonough, Kathleen; Bertolet, Marnie; Weissfeld, Joel L.; Catov, Janet M.; Modugno, Francesmary; Bunker, Clareann H.; Ness, Roberta B.; Diergaarde, Brenda

2014-01-01

Purpose Traditional disease-free survival (DFS) does not reflect changes in prognosis over time. Conditional DFS accounts for elapsed time since achieving remission and may provide more relevant prognostic information for patients and clinicians. This study aimed to estimate conditional DFS among patients with ovarian cancer and to evaluate the impact of patient characteristics. Patients and Methods Patients were recruited as part of the Hormones and Ovarian Cancer Prediction case-control study and were included in the current study if they had achieved remission after a diagnosis of cancer of the ovary, fallopian tube, or peritoneum (N = 404). Demographic and lifestyle information was collected at enrollment; disease, treatment, and outcome information was abstracted from medical records. DFS was calculated using the Kaplan-Meier method. Conditional DFS estimates were computed using cumulative DFS estimates. Results Median DFS was 2.54 years (range, 0.03-9.96 years) and 3-year DFS was 48.2%. The probability of surviving an additional 3 years without recurrence, conditioned on having already survived 1, 2, 3, 4, and 5 years after remission, was 63.8%, 80.5%, 90.4%, 97.0%, and 97.7%, respectively. Initial differences in 3-year DFS at time of remission between age, stage, histology, and grade groups decreased over time. Conclusion DFS estimates for patients with ovarian cancer improved dramatically over time, in particular among those with poorer initial prognoses. Conditional DFS is a more relevant measure of prognosis for patients with ovarian cancer who have already achieved a period of remission, and time elapsed since remission should be taken into account when making follow-up care decisions. PMID:25403208

Rapid heat-flowing surveying of geothermal areas, utilizing individual snowfalls as calorimeters

USGS Publications Warehouse

White, Donald E.

1969-01-01

Local differences in rate of heat transfer in vapor and by conduction through the ground in hot spring areas are difficult and time-consuming to measure quantitatively. Individual heavy snowfalls provide a rapid low-cost means of measuring total heat flow from such ground. After a favorable snowfall (heavy, brief duration, little wind, air temperature near 0°C), contacts between snow-covered and snow-free ground are mapped on a suitable base. Each mapped contact, as time elapses after a specific snowfall, is a heat-flow contour representing a decreasing rate of flow. Calibration of each mapped contact or snow line is made possible by the fact that snow remains on insulated surfaces (such as the boardwalks of Yellowstone's thermal areas) long after it has melted on adjacent warm ground. Heat-flow contours mapped to date range from 450 to 5500 μcal/cm2 sec, or 300 to 3700 times the world average of conductive heat flow. The very high rates of heat flow (2000 to > 10,000 μcal/cm2 sec) are probably too high, and the lower heat flows determinable by the method (2 sec) may be too low. Values indicated by the method are, however, probably within a factor of 2 of the total conductive and convective heat flow. Thermal anomalies from infrared imagery are similar in shape to heat-flow contours of a test area near Old Faithful geyser. Snowfall calorimetry provides a rapid means for evaluating the imagery and computer-derived products of the infrared data in terms of heat flow.

A first city-wide early defibrillation project in a German city: 5-year results of the Bochum against sudden cardiac arrest study

PubMed Central

2010-01-01

Background Immediate defibrillation is the decisive determinant of prognosis in patients suffering from cardiac/circulatory arrest caused by ventricular fibrillation (VF). Therefore, various national and international associations recommend that first responders use defibrillators as soon as possible and also recommend public access to early defibrillation programmes. Here we report the results of the first city-wide early defibrillation project in a large German urban area. Methods There were 155 automated external defibrillators (AEDs) put into operation in the Bochum municipal area, and 6,294 people took part in cardiopulmonary resuscitation (CPR) and AED training. Free, accessible AEDs were installed in places with large volumes of people. Additionally, emergency forces were progressively equipped with AEDs. Results Twelve AED administrations prior to the arrival of an emergency physician were recorded and analysed over a period of 5 years (08/2004-08/2009). Rhythm analysis via AED demonstrated VF in seven cases, non-malignant dysrhythmias in four cases and asystole in one case. Two of the seven patients with VF were successfully defibrillated and survived cardiac/circulatory arrest without any neurological sequelae. Eight of the 12 AED applications were performed by laymen. The mean time between switching the unit on and applying the electrodes to the patient was 39 seconds (SD +/-20 sec). On average, another 20 seconds elapsed before the AED recommendation of "shock delivery" was displayed, and a total of 96 seconds elapsed before shock administration (± 56 sec). Conclusion Consistent with other reports, our findings show that the organisation of a city-wide initiative by a project office combining public access and first-responder defibrillation programmes can be safe, feasible and successful. Our experiences confirm that strategic planning of AED placement is a prerequisite for successful, cost-effective resuscitation. PMID:20550655

BRL Particle Sizing Interferometer

DTIC Science & Technology

1982-07-01

satisfy the counting constraints required for entry into the ■ Histogran Counter. ACQUISITION TIME -~ The tiwe which elapsed during data acquistion ...weighted population (i.e., Measured population tines the weighting factor) of a bin in the particle size histogran acquistion . Does not include data...1000.0 40.0 3000 1 ZING FROM PSI OMHZ M MHZ MHZ V. VOLTS PED HZ ODE ON PAD ZCD=3.7 ADJUST OFF; IRIG HISTOGRAM E:ET 42.0 CLOCK

Aerial Photography: Use in Detecting Simulated Insect Defoliation in Corn

NASA Technical Reports Server (NTRS)

Chiang, H. C.; Latham, R.; Meyer, M. P.

1973-01-01

Artificial defoliation in corn was used to explore the usefulness of aerial photography in detecting crop insect infestations. Defoliation on the top of plants was easily detected, while that on the base was less so. Aero infrared film with Wratten 89B filter gave the best results, and morning flights at the scale of 1:15840 are recommended. Row direction, plant growth stage, and time elapse since defoliation were not important factors.

Disentangling the Dynamical Mechanisms for Cluster Galaxy Evolution

DTIC Science & Technology

2008-02-01

reversible energy and angular momentum exchange between the density wave and the disk matter and the outward transport of these exchanged energy and angular...elapsed time for a smaller z as well. Yet the argument should hold no matter what observation epoch one uses, as long as one concentrates to the regions... matter (CDM) paradigm, galaxy mergers are the preferred means of morphological evolution of galaxies in clusters (see, e.g., Kauffmann 1995). Even though

CALIOP Version 3 Data Products: A Comparison to Version 2

NASA Technical Reports Server (NTRS)

Vaughan, Mark; Omar, Ali; Hunt, Bill; Getzewich, Brian; Tackett, Jason; Powell, Kathy; Avery, Melody; Kuehn, Ralph; Young, Stuart; Hu, Yong;

Effect of time elapsed after prescribed burning in longleaf pine stands on potential prey of the red-cockaded woodpecker

Treesearch

Kirsten C. New; James L. Hanula

1998-01-01

The effects of dormant and growing season prescribed burns on the potential arthropod prey of the red-cockaded woodpecker (Picoides borealis) were studied in longleaf pine (Pinus palustris Mill.) stands on the upper Coastal Plain of South Carolina. Sampling was conducted 0, 1, 2, or 3 years post burn. Stands were burned once during the winters of 1991, 1992, 1993, and...

Physical Modeling Techniques for Missile and Other Protective Structures

DTIC Science & Technology

1983-06-29

uniaxial load only. In general , axial thrust was applied with an: initial eccentricity of zero on the specimen end. Sixteen different combinations of Pa...conditioning electronics and cabling schemes is included. The techniques described generally represent current approaches at the Civil Engineering Research...at T- zero and stopping when a pulse is generated by the pi-ezoelectric disc on arrival of! the detonation wave front. All elapsed time data is stored

Julian Date (J.D.)

NASA Astrophysics Data System (ADS)

Murdin, P.

2000-11-01

Also known as the Julian period, the number of days, and the fraction of a day, which have elapsed since noon on 1 January, 4713 BC. Thus 18.00 hours UT on 1 March 1980 corresponds to J.D. 2 4444 3000.25. For certain purposes, for example, when analyzing the frequency with which events occur over long periods of time, it is most convenient to use this system of dating. The Julian period was propo...

Characterization of poly(2-hydroxyethyl methacrylate) (PHEMA) contact lens using the Langmuir monolayer technique.

PubMed

Nogueira, N; Conde, O; Miñones, M; Trillo, J M; Miñones, J

2012-11-01

The behavior of poly(2-hydroxyethyl methacrylate) (PHEMA) polymer monolayer spread on water was studied under various experimental conditions. The influence of subphase pH and temperature, compression speed, elapsed time from the deposit of the monolayer and the recording of the surface pressure-area (π-A) isotherms, as well as the number of polymer molecules deposited at the air/water surface (surface concentration) was studied. The obtained results show that PHEMA exhibits a very stable monolayer given that it is unaffected by modifications in the majority of these variables. Only the elapsed time between the spreading of the monolayer and the beginning of compression causes a small change in the π-A isotherms that consists in an increase in the area occupied by the film. This is attributed to the greater unfolding with time of the polymer's monomers at the air/water interface. The plateau that appears on π-A curves of the PHEMA monolayer is attributed to the reorientation of their hydroxyethyl polar groups through their C-O-C bonds, as well as to the reorientation of the ethylene (CH(2)) groups that link the monomers, which provokes a folding of the polymer's chains causing an accordion configuration. The existence of this structure is confirmed by the presence of numerous noise peaks in the relative thickness versus time curve corresponding to this region. In the same fashion, the images observed from Brewster angle microscopy (BAM) reveal the existence of light-dark "bands" relative to the different regions of this particular structure. Copyright © 2012 Elsevier Inc. All rights reserved.

Persistently retained interferon-gamma responsiveness in individuals with a history of pulmonary tuberculosis.

PubMed

Seo, Kwang Won; Ahn, Jong-Joon; Ra, Seung Won; Kwon, Woon-Jung; Jegal, Yangjin

2014-06-01

The interferon gamma (IFN-γ) release assays (IGRAs) are the best method of detecting Mycobacterium tuberculosis infection. However, reports on IGRAs results obtained during and right after the treatment of tuberculosis (TB) have presented differing results. Some studies have shown declining responses, whereas other reports described persistent, fluctuating, or increasing responses. We postulated that the IGRA-positivity will decrease or revert long time after treatment of TB, and thus, evaluated the response of IGRA in subjects with a history of pulmonary TB. Seventy subjects (M:F = 51:19; age = 53.2 ± 11.8 years) underwent tuberculin skin tests (TSTs) and IGRA. The interval of time elapsed after the completion of anti-TB treatment was < 10 years for 16 subjects, 10-20 years for 13 subjects, 20-30 years for 16 subjects, and ≥ 30 years for 25 subjects. The TST was positive in 49 subjects (74%) and negative in 17 subjects (26%). The IGRA was positive in 52 subjects (74%) and negative in 18 subjects (26%). The IFN-γ level and the size of induration showed good correlation (r = 0.525, P < 0.001). However, the correlation between time elapsed after the completion of anti-TB treatment and the size of induration or that between time and the IFN-γ level was not significant. The TST and IGRA were positive in 72.7% and 68.0% of subjects ≥ 30 years after the treatment of pulmonary TB. In conclusion, majority of subjects with a history of pulmonary TB are IGRA-positive, even a few decades after the completion of anti-TB treatment.

Development of the Large-Scale Statistical Analysis System of Satellites Observations Data with Grid Datafarm Architecture

NASA Astrophysics Data System (ADS)

Yamamoto, K.; Murata, K.; Kimura, E.; Honda, R.

2006-12-01

In the Solar-Terrestrial Physics (STP) field, the amount of satellite observation data has been increasing every year. It is necessary to solve the following three problems to achieve large-scale statistical analyses of plenty of data. (i) More CPU power and larger memory and disk size are required. However, total powers of personal computers are not enough to analyze such amount of data. Super-computers provide a high performance CPU and rich memory area, but they are usually separated from the Internet or connected only for the purpose of programming or data file transfer. (ii) Most of the observation data files are managed at distributed data sites over the Internet. Users have to know where the data files are located. (iii) Since no common data format in the STP field is available now, users have to prepare reading program for each data by themselves. To overcome the problems (i) and (ii), we constructed a parallel and distributed data analysis environment based on the Gfarm reference implementation of the Grid Datafarm architecture. The Gfarm shares both computational resources and perform parallel distributed processings. In addition, the Gfarm provides the Gfarm filesystem which can be as virtual directory tree among nodes. The Gfarm environment is composed of three parts; a metadata server to manage distributed files information, filesystem nodes to provide computational resources and a client to throw a job into metadata server and manages data processing schedulings. In the present study, both data files and data processes are parallelized on the Gfarm with 6 file system nodes: CPU clock frequency of each node is Pentium V 1GHz, 256MB memory and40GB disk. To evaluate performances of the present Gfarm system, we scanned plenty of data files, the size of which is about 300MB for each, in three processing methods: sequential processing in one node, sequential processing by each node and parallel processing by each node. As a result, in comparison between the number of files and the elapsed time, parallel and distributed processing shorten the elapsed time to 1/5 than sequential processing. On the other hand, sequential processing times were shortened in another experiment, whose file size is smaller than 100KB. In this case, the elapsed time to scan one file is within one second. It implies that disk swap took place in case of parallel processing by each node. We note that the operation became unstable when the number of the files exceeded 1000. To overcome the problem (iii), we developed an original data class. This class supports our reading of data files with various data formats since it converts them into an original data format since it defines schemata for every type of data and encapsulates the structure of data files. In addition, since this class provides a function of time re-sampling, users can easily convert multiple data (array) with different time resolution into the same time resolution array. Finally, using the Gfarm, we achieved a high performance environment for large-scale statistical data analyses. It should be noted that the present method is effective only when one data file size is large enough. At present, we are restructuring the new Gfarm environment with 8 nodes: CPU is Athlon 64 x2 Dual Core 2GHz, 2GB memory and 1.2TB disk (using RAID0) for each node. Our original class is to be implemented on the new Gfarm environment. In the present talk, we show the latest results with applying the present system for data analyses with huge number of satellite observation data files.

Adherence to AHA Guidelines When Adapted for Augmented Reality Glasses for Assisted Pediatric Cardiopulmonary Resuscitation: A Randomized Controlled Trial

PubMed Central

Gervaix, Alain; Haddad, Kevin; Lacroix, Laurence; Schrurs, Philippe; Sahin, Ayhan; Lovis, Christian; Manzano, Sergio

2017-01-01

Background The American Heart Association (AHA) guidelines for cardiopulmonary resuscitation (CPR) are nowadays recognized as the world’s most authoritative resuscitation guidelines. Adherence to these guidelines optimizes the management of critically ill patients and increases their chances of survival after cardiac arrest. Despite their availability, suboptimal quality of CPR is still common. Currently, the median hospital survival rate after pediatric in-hospital cardiac arrest is 36%, whereas it falls below 10% for out-of-hospital cardiac arrest. Among emerging information technologies and devices able to support caregivers during resuscitation and increase adherence to AHA guidelines, augmented reality (AR) glasses have not yet been assessed. In order to assess their potential, we adapted AHA Pediatric Advanced Life Support (PALS) guidelines for AR glasses. Objective The study aimed to determine whether adapting AHA guidelines for AR glasses increased adherence by reducing deviation and time to initiation of critical life-saving maneuvers during pediatric CPR when compared with the use of PALS pocket reference cards. Methods We conducted a randomized controlled trial with two parallel groups of voluntary pediatric residents, comparing AR glasses to PALS pocket reference cards during a simulation-based pediatric cardiac arrest scenario—pulseless ventricular tachycardia (pVT). The primary outcome was the elapsed time in seconds in each allocation group, from onset of pVT to the first defibrillation attempt. Secondary outcomes were time elapsed to (1) initiation of chest compression, (2) subsequent defibrillation attempts, and (3) administration of drugs, as well as the time intervals between defibrillation attempts and drug doses, shock doses, and number of shocks. All these outcomes were assessed for deviation from AHA guidelines. Results Twenty residents were randomized into 2 groups. Time to first defibrillation attempt (mean: 146 s) and adherence to AHA guidelines in terms of time to other critical resuscitation endpoints and drug dose delivery were not improved using AR glasses. However, errors and deviations were significantly reduced in terms of defibrillation doses when compared with the use of the PALS pocket reference cards. In a total of 40 defibrillation attempts, residents not wearing AR glasses used wrong doses in 65% (26/40) of cases, including 21 shock overdoses >100 J, for a cumulative defibrillation dose of 18.7 Joules per kg. These errors were reduced by 53% (21/40, P<.001) and cumulative defibrillation dose by 37% (5.14/14, P=.001) with AR glasses. Conclusions AR glasses did not decrease time to first defibrillation attempt and other critical resuscitation endpoints when compared with PALS pocket cards. However, they improved adherence and performance among residents in terms of administering the defibrillation doses set by AHA. PMID:28554878

Ulcer due to chronic venous disease: a sociodemographic study in northeastern Brazil.

PubMed

de Souza, Edson Marques; Yoshida, Winston Bonetti; de Melo, Valdinaldo Aragão; Aragão, José Aderval; de Oliveira, Luiz Augusto Bitencurt

2013-07-01

Venous ulcers account for 70% of chronic leg ulcers and affect about 2-7% of the population, causing much socioeconomic impact and reducing patients' quality of life. In this study we aimed to describe the clinical features of venous ulcers and sociodemographic characteristics of patients with ulcers due to chronic venous disease (CVD). This cross-sectional, observational study was conducted at the Vascular Surgery Service, Universidade Federal de Sergipe, in northeastern Brazil. The study included a consecutive series of 154 patients with active venous ulcers (CEAP C6) in the lower limb due to CVD. Sociodemographic characteristics (age, gender, race, monthly income, education, occupation, and caregiver) and clinical data (affected limb, ulcer site, etiopathogenesis, recurrence, and time elapsed since the first episode of ulcer) were collected. A possible correlation of time elapsed since the first episode of ulcer and number of recurrences with primary or secondary etiology was analyzed by Mann-Whitney U-test. Of the 154 patients analyzed, 79% were female, 94% were ethnically black or brown, 90% had a monthly income less than or equal to minimum wage, 47% were illiterate, 35% had not completed elementary school, 50% had informal jobs, 19.5% were retired, and 18.2% received sick pay from the social security system. The mean age was 53.7 years. Both limbs were affected similarly, and venous ulcers were located predominantly on the medial aspect of the leg (84%). The median time elapsed since the first episode of ulcer was 36 months, being significantly higher in patients with venous ulcers of secondary etiology (P < 0.0003). The prevalence of recurrence was also significantly higher in patients with venous ulcers of secondary etiology (P < 0.001). According to CEAP classification, 65% of ulcers were primary (Ep), 94.1% demonstrated reflux involving the superficial system (As), 92% had incompetent perforators (Ap), 35% demonstrated reflux involving the deep system (Ad), and all ulcers showed reflux without obstruction (Pr). Venous ulcers were more prevalent among low-income patients, especially chronic, recurrent ulcers of primary etiology. This finding highlights the need for improvements in patient care and surgical treatment in most cases aimed at ulcer healing and reduced recurrence. Better care would improve patients' quality of life and reduce social security expenditures. Crown Copyright © 2013. Published by Elsevier Inc. All rights reserved.

Time from convulsive status epilepticus onset to anticonvulsant administration in children

PubMed Central

Sánchez Fernández, Iván; Abend, Nicholas S.; Agadi, Satish; An, Sookee; Arya, Ravindra; Brenton, James Nicholas; Carpenter, Jessica L.; Chapman, Kevin E.; Gaillard, William D.; Glauser, Tracy A.; Goodkin, Howard P.; Kapur, Kush; Mikati, Mohamad A.; Peariso, Katrina; Ream, Margie; Riviello, James; Tasker, Robert C.; Jackson, Michele

2015-01-01

Objective: To describe the time elapsed from onset of pediatric convulsive status epilepticus (SE) to administration of antiepileptic drug (AED). Methods: This was a prospective observational cohort study performed from June 2011 to June 2013. Pediatric patients (1 month–21 years) with convulsive SE were enrolled. In order to study timing of AED administration during all stages of SE, we restricted our study population to patients who failed 2 or more AED classes or needed continuous infusions to terminate convulsive SE. Results: We enrolled 81 patients (44 male) with a median age of 3.6 years. The first, second, and third AED doses were administered at a median (p25–p75) time of 28 (6–67) minutes, 40 (20–85) minutes, and 59 (30–120) minutes after SE onset. Considering AED classes, the initial AED was a benzodiazepine in 78 (96.3%) patients and 2 (2–3) doses of benzodiazepines were administered before switching to nonbenzodiazepine AEDs. The first and second doses of nonbenzodiazepine AEDs were administered at 69 (40–120) minutes and 120 (75–296) minutes. In the 64 patients with out-of-hospital SE onset, 40 (62.5%) patients did not receive any AED before hospital arrival. In the hospital setting, the first and second in-hospital AED doses were given at 8 (5–15) minutes and 16 (10–40) minutes after SE onset (for patients with in-hospital SE onset) or after hospital arrival (for patients with out-of-hospital SE onset). Conclusions: The time elapsed from SE onset to AED administration and escalation from one class of AED to another is delayed, both in the prehospital and in-hospital settings. PMID:25948729

Windowed cross-correlation and peak picking for the analysis of variability in the association between behavioral time series.

PubMed

Boker, Steven M; Xu, Minquan; Rotondo, Jennifer L; King, Kadijah

2002-09-01

Cross-correlation and most other longitudinal analyses assume that the association between 2 variables is stationary. Thus, a sample of occasions of measurement is expected to be representative of the association between variables regardless of the time of onset or number of occasions in the sample. The authors propose a method to analyze the association between 2 variables when the assumption of stationarity may not be warranted. The method results in estimates of both the strength of peak association and the time lag when the peak association occurred for a range of starting values of elapsed time from the beginning of an experiment.

Method for reducing peak phase current and decreasing staring time for an internal combustion engine having an induction machine

DOEpatents

Amey, David L.; Degner, Michael W.

2002-01-01

A method for reducing the starting time and reducing the peak phase currents for an internal combustion engine that is started using an induction machine starter/alternator. The starting time is reduced by pre-fluxing the induction machine and the peak phase currents are reduced by reducing the flux current command after a predetermined period of time has elapsed and concurrent to the application of the torque current command. The method of the present invention also provides a strategy for anticipating the start command for an internal combustion engine and determines a start strategy based on the start command and the operating state of the internal combustion engine.

Time course of the uridylylation and adenylylation states in the glutamine synthetase bicyclic cascade.

PubMed Central

Varón-Castellanos, R; Havsteen, B H; García-Moreno, M; Valero-Ruiz, E; Molina-Alarcón, M; García-Cánovas, F

1993-01-01

A kinetic analysis of the glutamine synthetase bicyclic cascade is presented. It includes the dependence on time from the onset of the reaction of both the uridylylation of Shapiro's regulatory protein and the adenylylation of the glutamine synthetase. The transient phase equations obtained allow an estimation of the time elapsed until the states of uridylylation and adenylylation reach their steady-states, and therefore an evaluation of the effective sensitivity of the system. The contribution of the uridylylation cycle to the adenylylation cycle has been studied, and an equation relating the state of adenylylation at any time to the state of uridylylation at the same instant has been derived. PMID:8104399

Misdiagnosed Chest Pain: Spontaneous Esophageal Rupture

PubMed Central

Inci, Sinan; Gundogdu, Fuat; Gungor, Hasan; Arslan, Sakir; Turkyilmaz, Atila; Eroglu, Atila

2013-01-01

Chest pain is one of themost common complaints expressed by patients presenting to the emergency department, and any initial evaluation should always consider life-threatening causes. Esophageal rupture is a serious condition with a highmortality rate. If diagnosed, successful therapy depends on the size of the rupture and the time elapsed between rupture and diagnosis.We report on a 41-year-old woman who presented to the emergency department complaining of left-sided chest pain for two hours. PMID:27122690

Data-Logger Interface And Test Controller

NASA Technical Reports Server (NTRS)

Burch, Donnie R.

1995-01-01

Data-logger interface and test controller developed to enable automation of tests in conjunction with data-acquisition functions performed by data loggers that have output-switching capabilities. Includes relay logic circuits that remain deenergized until out-of-tolerance condition on any data channel discovered. Designed to be connected to Fluke model 2286A (or equivalent) data-logger system, which features 3 control channels with 6 data inputs per channel. Includes elapsed-time counter that keeps track of power outages.

STS098-s-017

NASA Image and Video Library

2001-02-20

STS098-S-017 (20 Feb. 2001) --- A drag chute slows down the space shuttle Atlantis following its touchdown to mark mission completion at Edwards Air Force Base in the Mojave Desert of California. Onboard were astronauts Kenneth Cockrell, Mark Polansky, Robert Curbeam, Thomas Jones and Marsha Ivins. Atlantis touched down on Edward?s concrete runway at 2:33 p.m. (CST), Feb. 20, for a mission elapsed time of 12 days, 21 hours and 20 minutes. Photo credit: NASA

New Orleans area as seen from the Apollo 7 spacecraft

NASA Image and Video Library

1968-10-19

The greater New Orleans area, including portions of Louisiana and Mississippi, as seen from the Apollo 7 spacecraft during its 120th revolution of the earth. Photographed from an altitude of 95 nautical miles, at ground elapsed time of 190 hours and 45 minutes. The largest body of water in the picture is Lake Pontchartrain. The Mississippi River is clearly visible as it meanders past New Orleans. Note highway network, and 25-mile causeway across lake.

MEANS FOR VISUALIZING FLUID FLOW PATTERNS

DOEpatents

Lynch, F.E.; Palmer, L.D.; Poppendick, H.F.; Winn, G.M.

1961-05-16

An apparatus is given for determining both the absolute and relative velocities of a phosphorescent fluid flowing through a transparent conduit. The apparatus includes a source for exciting a narrow trsnsverse band of the fluid to phosphorescence, detecting means such as a camera located downstream from the exciting source to record the shape of the phosphorescent band as it passes, and a timer to measure the time elapsed between operation of the exciting source and operation of the camera.

So You Want To Earn a PH.D. in Economics: How Long Do You Think It Will Take? Discussion Paper.

ERIC Educational Resources Information Center

Siegfried, John J.; Stock, Wendy A.

The elapsed time taken to earn a Ph.D. in economics is analyzed with data from 620 (of about 950) 1996-1997 Ph.D.s. The median is 5.3 years. A duration model indicates that those students at several of the most highly regarded programs, those supported by no-work fellowships, and those holding a prior master's degree finish faster than others.…

The role of self-determined motivation in job search: A dynamic approach.

PubMed

da Motta Veiga, Serge P; Gabriel, Allison S

2016-03-01

Job search is a dynamic self-regulated process during which job seekers need to stay motivated to secure a job. However, past research has taken a relatively static approach to examining motivation during the job search, in addition to ignoring how the quality of one's motivation--ranging from autonomous to controlled--can influence job search processes. Adopting a within-person perspective, the current study extends self-determination theory (SDT) to the job search context to investigate (a) when autonomous and controlled motivations are more or less prevalent and (b) whether they influence job search effort through metacognitive strategies in differing ways depending upon the amount of time elapsed in the search. In a weekly study of new labor market entrants (Level-2 n = 149; Level-1 n = 691), results indicated that autonomous motivation decreased until the midpoint of the job search and then plateaued, whereas controlled motivation remained stable. Results also showed that autonomous motivation had a consistent, positive relation with metacognitive strategies, whereas the relation between controlled motivation and such strategies was negative early in the job search, but became positive as the job search progressed. Finally, the effects of motivation on job search effort occurred via metacognitive strategies differentially depending upon the time elapsed in the search. Combined, we provide a first glimpse into the dynamics of self-determined motivation on job search processes. (c) 2016 APA, all rights reserved).

Newton, Laplace, and The Epistemology of Systems Biology

PubMed Central

Bittner, Michael L.; Dougherty, Edward R.

2012-01-01

For science, theoretical or applied, to significantly advance, researchers must use the most appropriate mathematical methods. A century and a half elapsed between Newton’s development of the calculus and Laplace’s development of celestial mechanics. One cannot imagine the latter without the former. Today, more than three-quarters of a century has elapsed since the birth of stochastic systems theory. This article provides a perspective on the utilization of systems theory as the proper vehicle for the development of systems biology and its application to complex regulatory diseases such as cancer. PMID:23170064

Fire impact on forest soils evaluated using near-infrared spectroscopy and multivariate calibration.

PubMed

Vergnoux, A; Dupuy, N; Guiliano, M; Vennetier, M; Théraulaz, F; Doumenq, P

2009-11-15

The assessment of physico-chemical properties in forest soils affected by fires was evaluated using near infrared reflectance (NIR) spectroscopy coupled with chemometric methods. In order to describe the soil properties, measurements were taken of the total organic carbon on solid phase, the total nitrogen content, the organic carbon and the specific absorbences at 254 and 280 nm of humic substances, organic carbon in humic and fulvic acids, concentrations of NH(4)(+), Ca(2+), Mg(2+), K(+) and phosphorus in addition to NIR spectra. Then, a fire recurrence index was defined and calculated according to the different fires extents affecting soils. This calculation includes the occurrence of fires as well as the time elapsed since the last fire. This study shows that NIR spectroscopy could be considered as a tool for soil monitoring, particularly for the quantitative prediction of the total organic carbon, total nitrogen content, organic carbon in humic substances, concentrations of phosphorus, Mg(2+), Ca(2+) and NH(4)(+) and humic substances UVSA(254). Further validation in this field is necessary however, to try and make successful predictions of K(+), organic carbon in humic and fulvic acids and the humic substances UVSA(280). Moreover, NIR coupled with PLS can also be useful to predict the fire recurrence index in order to determine the spatial variability. Also this method can be used to map more or less burned areas and possibly to apply adequate rehabilitation techniques, like soil litter reconstitution with organic enrichments (industrial composts) or reforestation. Finally, the proposed recurrence index can be considered representative of the state of the soils.

Challenges to tracking subjects for follow-up research: a case study.

PubMed

Fenster, Judy

2009-01-01

This narrative presents issues faced by the author and her research assistants in attempting to locate 40 subjects who had participated in a child welfare research study two decades earlier. The experience of the researchers suggests that attempting to locate subjects, especially where contact has not been maintained over the years, may not be accomplished without considerable time and expense. The author reflects on possible contributors to the difficulties in contacting these participants, highlights some recent developments in techniques for locating subjects after long periods of time have elapsed, and discusses some relevant ethical dilemmas.

KSC-07pd3189

NASA Image and Video Library

2007-11-07

KENNEDY SPACE CENTER, FLA. -- STS-120 mission specialist Scott Parazynski is happy to back at NASA's Kennedy Space Center after the 15-day mission to the International Space Station. The Discovery crew completed mission STS-120 with an on-time landing at 1:01:16 p.m. Wheel stop was at 1:02:07 p.m. Mission elapsed time was 15 days, 2 hours, 24 minutes and 2 seconds. Mission STS-120 continued the construction of the station with the installation of the Harmony Node 2 module and the relocation of the P6 truss. Photo credit: NASA/Kim Shiflett

KSC-07pd3187

NASA Image and Video Library

2007-11-07

KENNEDY SPACE CENTER, FLA. -- STS-120 Pilot George Zamka is happy to be back at NASA's Kennedy Space Center after the 15-day mission to the International Space Station aboard space shuttle Discovery. The Discovery crew completed mission STS-120 with an on-time landing at 1:01:16 p.m. Wheel stop was at 1:02:07 p.m. Mission elapsed time was 15 days, 2 hours, 24 minutes and 2 seconds. Mission STS-120 continued the construction of the station with the installation of the Harmony Node 2 module and the relocation of the P6 truss. Photo credit: NASA/Kim Shiflett

KSC-07pd3190

NASA Image and Video Library

2007-11-07

KENNEDY SPACE CENTER, FLA. -- STS-120 Doug Wheelock is happy to back at NASA's Kennedy Space Center after the 15-day mission to the International Space Station aboard space shuttle Discovery. The Discovery crew completed mission STS-120 with an on-time landing at 1:01:16 p.m. Wheel stop was at 1:02:07 p.m. Mission elapsed time was 15 days, 2 hours, 24 minutes and 2 seconds. Mission STS-120 continued the construction of the station with the installation of the Harmony Node 2 module and the relocation of the P6 truss. Photo credit: NASA/Kim Shiflett

KSC-07pd3186

NASA Image and Video Library

2007-11-07

KENNEDY SPACE CENTER, FLA. -- STS-120 mission specialist Stephanie Wilson is happy to be back at NASA's Kennedy Space Center after the 15-day mission to the International Space Station aboard space shuttle Discovery. The Discovery crew completed mission STS-120 with an on-time landing at 1:01:16 p.m. Wheel stop was at 1:02:07 p.m. Mission elapsed time was 15 days, 2 hours, 24 minutes and 2 seconds. Mission STS-120 continued the construction of the station with the installation of the Harmony Node 2 module and the relocation of the P6 truss. Photo credit: NASA/Kim Shiflett

KSC-06pd1580

NASA Image and Video Library

2006-07-17

KENNEDY SPACE CENTER, FLA. - LeRoy Cain, manager of Shuttle Launch Integration, and Michael Fossum, STS-121 mission specialist, take a look at the orbiter Discovery during the traditional post-flight walk-around after the landing. Discovery's smooth and perfect landing was on time at 9:14 a.m. EDT on Runway 15 of NASA's Shuttle Landing Facility after traveling 5.3 million miles on 202 orbits. Mission elapsed time was 12 days, 18 hours, 37 minutes and 54 seconds. The landing is the 62nd at Kennedy Space Center and the 32nd for Discovery. Photo credit: NASA/Kim Shiflett

KSC-06pd1583

NASA Image and Video Library

2006-07-17

KENNEDY SPACE CENTER, FLA. - During the traditional post-flight walk-around after the landing of an orbiter, NASA Administrator Mike Griffin (right) shares a story with STS-121 Pilot Mark Kelly, Mission Specialist Lisa Nowak and Commander Steven Lindsey. Discovery's smooth and perfect landing was on time at 9:14 a.m. EDT on Runway 15 of NASA's Shuttle Landing Facility after traveling 5.3 million miles on 202 orbits. Mission elapsed time was 12 days, 18 hours, 37 minutes and 54 seconds. The landing is the 62nd at Kennedy Space Center and the 32nd for Discovery. Photo credit: NASA/Kim Shiflett

KSC-06pd1578

NASA Image and Video Library

2006-07-17

KENNEDY SPACE CENTER, FLA. - During the traditional post-flight walk-around after the landing of an orbiter, crew members Michael Fossum, mission specialist, and Steven Lindsey, commander, talk with NASA Administrator Mike Griffin (left). At right is Associate Administrator Rex Geveden. Discovery's smooth and perfect landing was on time at 9:14 a.m. EDT on Runway 15 of NASA's Shuttle Landing Facility after traveling 5.3 million miles on 202 orbits. Mission elapsed time was 12 days, 18 hours, 37 minutes and 54 seconds. The landing is the 62nd at Kennedy Space Center and the 32nd for Discovery. Photo credit: NASA/Kim Shiflett

KSC-06pd1581

NASA Image and Video Library

2006-07-17

KENNEDY SPACE CENTER, FLA. - During the traditional post-flight walk-around after the landing of an orbiter, Mission Specialists Piers Sellers, Michael Fossum and Stephanie Wilson get a close look at the nose cone, behind them. Discovery's smooth and perfect landing was on time at 9:14 a.m. EDT on Runway 15 of NASA's Shuttle Landing Facility after traveling 5.3 million miles on 202 orbits. Mission elapsed time was 12 days, 18 hours, 37 minutes and 54 seconds. The landing is the 62nd at Kennedy Space Center and the 32nd for Discovery. Photo credit: NASA/Kim Shiflett

Adrenal Hormones in Common Bottlenose Dolphins (Tursiops truncatus): Influential Factors and Reference Intervals

PubMed Central

Hart, Leslie B.; Wells, Randall S.; Kellar, Nick; Balmer, Brian C.; Hohn, Aleta A.; Lamb, Stephen V.; Rowles, Teri; Zolman, Eric S.; Schwacke, Lori H.

2015-01-01

Inshore common bottlenose dolphins (Tursiops truncatus) are exposed to a broad spectrum of natural and anthropogenic stressors. In response to these stressors, the mammalian adrenal gland releases hormones such as cortisol and aldosterone to maintain physiological and biochemical homeostasis. Consequently, adrenal gland dysfunction results in disruption of hormone secretion and an inappropriate stress response. Our objective herein was to develop diagnostic reference intervals (RIs) for adrenal hormones commonly associated with the stress response (i.e., cortisol, aldosterone) that account for the influence of intrinsic (e.g., age, sex) and extrinsic (e.g., time) factors. Ultimately, these reference intervals will be used to gauge an individual’s response to chase-capture stress and could indicate adrenal abnormalities. Linear mixed models (LMMs) were used to evaluate demographic and sampling factors contributing to differences in serum cortisol and aldosterone concentrations among bottlenose dolphins sampled in Sarasota Bay, Florida, USA (2000–2012). Serum cortisol concentrations were significantly associated with elapsed time from initial stimulation to sample collection (p<0.05), and RIs were constructed using nonparametric methods based on elapsed sampling time for dolphins sampled in less than 30 minutes following net deployment (95% RI: 0.91–4.21 µg/dL) and following biological sampling aboard a research vessel (95% RI: 2.32–6.68 µg/dL). To examine the applicability of the pre-sampling cortisol RI across multiple estuarine stocks, data from three additional southeast U.S. sites were compared, revealing that all of the dolphins sampled from the other sites (N = 34) had cortisol concentrations within the 95th percentile RI. Significant associations between serum concentrations of aldosterone and variables reported in previous studies (i.e., age, elapsed sampling time) were not observed in the current project (p<0.05). Also, approximately 16% of Sarasota Bay bottlenose dolphin aldosterone concentrations were below the assay’s detection limit (11 pg/mL), thus hindering the ability to derive 95th percentile RIs. Serum aldosterone concentrations from animals sampled at the three additional sites were compared to the detection limit, and the proportion of animals with low aldosterone concentrations was not significantly different than an expected prevalence of 16%. Although this study relied upon long-term, free-ranging bottlenose dolphin health data from a single site, the objective RIs can be used for future evaluation of adrenal function among individuals sampled during capture-release health assessments. PMID:25993341

The influence of social support from the family on health related-quality of life in persons with a colostomy.

PubMed

Leyk, Magdalena; Ksiaz˙ek, Janina; Habel, Agnieszka; Dobosz, Marek; Kruk, Agnieszka; Terech, Sylwia

2014-01-01

We evaluated the influence of social support on health-related quality of life (HRQOL) in persons with a colostomy, taking into account time since surgery. The study was conducted in 8 cities in Poland. The sample comprised 128 patients with a colostomy; their mean age was 66.24 years. Forty-five percent of participants had lived with a colostomy for more than 5 years, and 16% had a colostomy for less than 1 year. The questionnaire used in the study included 76 questions divided into 3 parts. The first part comprised 8 questions that queried demographic characteristics. Parts 2 and 3 included 2 validated scales assessing HRQOL and social support, respectively. Health-related quality of life was assessed using the Functional Assessment of Cancer Therapy-Colorectal instrument. Social support received was assessed using the Berlin Social Support Scale. In the case of both scales, the respondents were asked to assess their status during the last 7 days. The study was conducted by an interviewer during monthly meetings of colostomy support groups as well as during hospitalization. The respondents gave their verbal answers to questions read by the interviewer or completed the questionnaires by themselves. After the questionnaire was completed, the interviewer verified completeness of answers. The outcome time elapsed since surgery was categorized as 3 subgroups: (1) respondents having a colostomy 1 year or less, (2) respondents having colostomy for more than 1 or up to 5 years, and (3) respondents having colostomy more than 5 years. Analysis revealed a statistically significant relationship between level of social support and HRQOL among persons with a colostomy (R = 0.361, P = .000029). Moreover, we observed that the time elapsed since colostomy surgery influenced this relationship. Level of social support and HRQOL were not significantly related in persons living with a colostomy ≤1 year (R = 0.155, P = .525). The correlation was significant in persons with a colostomy for more than 1 to but less than 5 years (R = 0.329, P = .02), and in individuals living with a colostomy for more than 5 years (R = 0.482, P = .0001). Persons with permanent colostomies and the higher level of social support from family reported higher HRQOL than did persons with lower levels of social support. Time elapsed since colostomy surgery exerts a positive effect on this relationship; the longer the patients live with a colostomy, the greater the influence of social support.

Quantitative changes in the biochemical composition of lignocellulosic residues during the vegetative growth of Lentinula edodes

PubMed Central

Gaitán-Hernández, Rigoberto; Esqueda, Martín; Gutiérrez, Aldo; Beltrán-García, Miguel

2011-01-01

The chemical changes in barley-straw (BS), wheat-straw (WS) and vineyard-pruning (VP) substrates were determined during colonization of Lentinula edodes mycelia (during primordium development) in solid state fermentation. Primordia appeared 39-50 days after inoculation. VP appeared to promote early sporophore initiation. The concentration of hemicellulose in BS and VP decreased gradually from 25.5% to 15.6% and from 15.8% to 12.3%, respectively. However in WS, hemicellulose decreased from 27.2% to 9.5%. Lignin broke down continuously in BS and WS, with 31.8% and 34.4% degradation, respectively; higher than that of cellulose. During the pinning stage, the C:N ratio decreased in VP and BS, but not in WS. On all substrates the phenols decreased notably throughout the first week of mycelial growth. The time elapsed (days) to pinning was positively correlated with cellulose content (r=0.89), total sugar (r=0.85) and inversely correlated to lignin (r=−1.00) and phenol content (r=−0.55). PMID:24031601

Microbial structural diversity estimated by dilution-extinction of phenotypic traits and T-RFLP analysis along a land-use intensification gradient

NASA Technical Reports Server (NTRS)

Gomez, Elena del V.; Garland, Jay L.; Roberts, Michael S.

2004-01-01

The present work tested whether the relationship between functional traits and inoculum density reflected structural diversity in bacterial communities from a land-use intensification gradient applying a mathematical model. Terminal restriction fragment length polymorphism (T-RFLP) analysis was also performed to provide an independent assessment of species richness. Successive 10-fold dilutions of a soil suspension were inoculated onto Biolog GN(R) microplates. Soil bacterial density was determined by total cell and plate counts. The relationship between phenotypic traits and inoculum density fit the model, allowing the estimation of maximal phenotypic potential (Rmax) and inoculum density (KI) at which Rmax will be half-reduced. Though Rmax decreased with time elapsed since clearing of native vegetation, KI remained high in two of the disturbed sites. The genetic pool of bacterial community did not experience a significant reduction, but the active fraction responding in the Biolog assay was adversely affected, suggesting a reduction in the functional potential. c2004 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.

Non-resident fathers' relationships with their secondary school age children: determinants and children's mental health outcomes.

PubMed

Flouri, Eirini

2006-08-01

Data from 520 British secondary school age children were used to explore determinants of and mental health outcomes (measured with the Strengths and Difficulties Questionnaire) from their non-resident fathers' relationships (child-reported father's involvement and frequency of contact) with them. Frequency of contact was negatively related to time elapsed since parents separated, and was higher if fathers were single than partnered. Compared to White, non-White adolescents reported lower frequency of father's contact but not lower father's involvement. Father's involvement was related positively to mother's involvement and negatively to interparental conflict. As a whole, non-resident father's involvement and frequency of contact did not improve the regression models predicting children's total difficulties or pro-social behaviour. Even after controlling for other factors non-resident father's involvement did not predict child's difficulties or pro-social behaviour, although frequency of contact was negatively associated with child's emotional symptoms. Neither child's ethnicity or gender nor mother's partner status moderated the link between child's mental health outcomes and non-resident father's involvement or frequency of contact.

In vitro efficacy of synthetic skin repellent IR3535 on head lice (Pediculus capitis).

PubMed

Rupes, Vaclav; Vlckova, Jana; Kollarova, Helena; Horakova, Dagmar; Mazanek, Libor; Kensa, Michal

2013-10-01

In in vitro tests, skin repellent IR3535, applied in the form of the Diffusil H Prevental product in an aerosol bomb (active compound 20%), killed 100% of head lice (females and males) and nymphs 2 and 3, when directly sprayed at a dose of 0.94 mg of the active compound per square centimeter. Crawling lice exposed for 1 min on the filter paper impregnated by the same concentration showed no effort to suck blood 30 min after exposition. Twenty hours later, their mortality rate was 11 %. After the lice had been exposed for approximately 1 min (until they actively left the area) on 5 cm round areas of skin of test persons treated with the repellent at a mean total dose of 23.3 mg of active compound, they showed no effort to suck blood on the clean skin of other test person either immediately after exposure or 30 min later. Their mortality after 20 h ranged from 59 to 16%, depending on the time elapsed from skin treatment (10 min to 27 h).

Subjective time runs faster under the influence of bright rather than dim light conditions during the forenoon.

PubMed

Morita, Takeshi; Fukui, Tomoe; Morofushi, Masayo; Tokura, Hiromi

2007-05-16

The study investigated if 6 h morning bright light exposure, compared with dim light exposure, could influence time sense (range: 5-15 s). Eight women served as participants. The participant entered a bioclimatic chamber at 10:00 h on the day before the test day, where an ambient temperature and relative humidity were controlled at 25 degrees C and 60%RH. She sat quietly in a sofa in 50 lx until 22:00 h, retired at 22:00 h and then slept in total darkness. She rose at 07:00 h the following morning and again sat quietly in a sofa till 13:00 h, either in bright (2500 lx) or dim light (50 lx), the order of light intensities between the two occasions being randomized. The time-estimation test was performed from 13:00 to 13:10 h in 200 lx. The participant estimated the time that had elapsed between two buzzers, ranging over 5-15 s, and inputting the estimate into a computer. The test was carried out separately upon each individual. Results showed that the participants estimated higher durations of the given time intervals after previous exposure to 6 h of bright rather than dim light. The finding is discussed in terms of different load errors (difference between the actual core temperature and its thermoregulatory set-point) following 6-h exposure to bright or dim light in the morning.

The onset time of amiodarone-induced thyrotoxicosis (AIT) depends on AIT type.

PubMed

Tomisti, Luca; Rossi, Giuseppe; Bartalena, Luigi; Martino, Enio; Bogazzi, Fausto

2014-09-01

Considering the different pathogenic mechanisms of the two main forms of amiodarone-induced thyrotoxicosis (AIT), we ascertained whether this results in a different onset time as well. We retrospectively analyzed the clinical records of 200 consecutive AIT patients (157 men and 43 women; mean age 62.2±12.6 years) referred to our Department from 1987 to 2012. The onset time of AIT was defined as the time elapsed from the beginning of amiodarone therapy and the first diagnosis of thyrotoxicosis, expressed in months. Factors associated with the onset time of AIT were evaluated by univariate and multivariate analyses. The median onset time of thyrotoxicosis was 3.5 months (95% CI 2-6 months) in patients with type 1 AIT (AIT1) and 30 months (95% CI 27-32 months, P<0.001) in those with type 2 AIT (AIT2). Of the total number of patients, 5% with AIT1 and 23% with AIT2 (P=0.007) developed thyrotoxicosis after amiodarone withdrawal. Factors affecting the onset time of thyrotoxicosis were the type of AIT and thyroid volume (TV). The different pathogenic mechanisms of the two forms of AIT account for different onset times of thyrotoxicosis in the two groups. Patients with preexisting thyroid abnormalities (candidate to develop AIT1) may require a stricter follow-up during amiodarone therapy than those usually recommended. In AIT1, the onset of thyrotoxicosis after amiodarone withdrawal is rare, while AIT2 patients may require periodic tests for thyroid function longer after withdrawing amiodarone. © 2014 European Society of Endocrinology.

Large-Scale Simulation Network Design Study

DTIC Science & Technology

1983-10-01

video displays: three for the tank commander, three for the driver, one for the loader, and one for the gunner. The solid angles subtended by these...Newman Inc Range Sortr This process sorts the expanded display lists into range order for drawing according to the "painter’s algorithm’" The range sorter ...session could then be continued as soon as the network recovered. and the elapsed session time would not be wasted . The SimNet design is much more tolerant

Green analytical chemistry--theory and practice.

PubMed

Tobiszewski, Marek; Mechlińska, Agata; Namieśnik, Jacek

2010-08-01

This tutorial review summarises the current state of green analytical chemistry with special emphasis on environmentally friendly sample preparation techniques. Green analytical chemistry is a part of the sustainable development concept; its history and origins are described. Miniaturisation of analytical devices and shortening the time elapsing between performing analysis and obtaining reliable analytical results are important aspects of green analytical chemistry. Solventless extraction techniques, the application of alternative solvents and assisted extractions are considered to be the main approaches complying with green analytical chemistry principles.

VA Health Care: Improved Monitoring Needed for Effective Oversight of Care for Women Veterans

DTIC Science & Technology

2016-12-01

November 2014. VHA officials also said that after reviewing information from sources such as veteran surveys and feedback from regional VA business...authorizations for care (of both men and women) from early calendar year 2016. In one case, almost a month and a half elapsed from the time of the...veteran’s initial pregnancy confirmation appointment at VA (when she was 6 weeks pregnant) to when the Choice authorization was sent by the VA facility to

[Telephone consultations on exposure to nuclear disaster radiation].

PubMed

Yashima, Sachiko; Chida, Koichi

2014-03-01

The Fukushima nuclear disaster occurred on March 11, 2011. For about six weeks, I worked as a counselor for phone consultations regarding radiation risk. I analyzed the number of consultations, consultations by telephone, and their changing patterns with elapse of time, to assist with consultations about risk in the future. There were a large number of questions regarding the effects of radiation, particularly with regard to children. We believe that counseling and risk communication are the key to effectively informing the public about radiation risks.

Did the Preflood Earth Have a 30-Day Lunar Month

DTIC Science & Technology

2015-01-01

moonfact.html. 2. R. A. Parker, “ Ancient Egyptian astronomy ,” Philosophical Transactions of the Royal Society of London. Series A, Math- ematical and Physical...many ancient writings indicate that at one time there was a 30-day lunar month. Genesis 7:11, 7:24, and 8:3-4 tell us that exactly 5 months elapsed...early calendars still used a 30-day month. Ancient Egyptian astronomers divided the year into three seasons, each with four 30-day months. Then to

Financing a voucher program for cocaine abusers through community donations in Spain.

PubMed

García-Rodríguez, Olaya; Secades-Villa, Roberto; Higgins, Stephen T; Fernández-Hermida, José R; Carballo, José L

2008-01-01

This study analyzed the viability of financing a voucher program for cocaine addicts in Spain through public and private donations. Of the 136 companies contacted, 52 (38%) provided donations. The difference between the benefits (15,670 Euro/ $20,371) and the costs (3734 Euro/ $4854) was 11,936 Euro/ $15,517. The type of reinforcer a company can offer, the size of the company, and the time elapsed before responding may be determining variables in a company's decision whether to collaborate.

Apparatus for measuring particle properties

DOEpatents

Rader, Daniel J.; Castaneda, Jaime N.; Grasser, Thomas W.; Brockmann, John E.

1998-01-01

An apparatus for determining particle properties from detected light scattered by the particles. The apparatus uses a light beam with novel intensity characteristics to discriminate between particles that pass through the beam and those that pass through an edge of the beam. The apparatus can also discriminate between light scattered by one particle and light scattered by multiple particles. The particle's size can be determined from the intensity of the light scattered. The particle's velocity can be determined from the elapsed time between various intensities of the light scattered.

Program design for incentivizing ignition interlock installation for alcohol-impaired drivers: The Ontario approach.

PubMed

Ma, Tracey; Byrne, Patrick A; Bhatti, Junaid A; Elzohairy, Yoassry

2016-10-01

Drinking and driving is a major risk factor for traffic injuries. Although ignition interlocks reduce drinking and driving while installed, several issues undermine their implementation including delayed eligibility for installation, low installation once eligible, and a return to previous risk levels after de-installation. The Canadian province of Ontario introduced a "Reduced Suspension with Ignition Interlock Conduct Review" Program, significantly changing pre-existing interlock policy. The Program incentivizes interlock installation and an "early" guilty plea. It also attempts to reduce long-term recidivism through behavioural feedback and compliance-based removal. This evaluation is the first in assessing Program impact. Ontario drivers with a first time alcohol-impaired driving conviction between July 1, 2005 and November 25, 2014 comprised the study cohort. Longitudinal analyses, using interrupted time series and Cox regression, were conducted in which exposure was the Program and the outcomes were ignition interlock installation (N=30,200), pre-trial elapsed time (N=30,200), and post-interlock recidivism (N=9326). After Program implementation, installation rates increased by 54% and pre-trial elapsed time decreased by 146 days. Results suggest no effect on post-interlock recidivism. Through an incentive-based design, this Program was effective at addressing two commonly cited barriers to interlock implementation- delayed eligibility for installation and low installation once eligible. Results reveal that installation rates are responsive not only to incentivization but also to other external factors, thus presenting an opportunity for policy makers to find unique ways to influence interlock uptake, and thereby, to extend their deterrent effects to a larger subset of the population. This study is one of the few that do not rely on proxy measures of installation rate. Copyright © 2016 Crown. Published by Elsevier Ltd.. All rights reserved.

Risk Factors for Hearing Decrement Among U.S. Air Force Aviation-Related Personnel.

PubMed

Greenwell, Brandon M; Tvaryanas, Anthony P; Maupin, Genny M

2018-02-01

The purpose of this study was to analyze historical hearing sensitivity data to determine factors associated with an occupationally significant change in hearing sensitivity in U.S. Air Force aviation-related personnel. This study was a longitudinal, retrospective cohort analysis of audiogram records for Air Force aviation-related personnel on active duty during calendar year 2013 without a diagnosis of non-noise-related hearing loss. The outcomes of interest were raw change in hearing sensitivity from initial baseline to 2013 audiogram and initial occurrence of a significant threshold shift (STS) and non-H1 audiogram profile. Potential predictor variables included age and elapsed time in cohort for each audiogram, gender, and Air Force Specialty Code. Random forest analyses conducted on a learning sample were used to identify relevant predictor variables. Mixed effects models were fitted to a separate validation sample to make statistical inferences. The final dataset included 167,253 nonbaseline audiograms on 10,567 participants. Only the interaction between time since baseline audiogram and age was significantly associated with raw change in hearing sensitivity by STS metric. None of the potential predictors were associated with the likelihood for an STS. Time since baseline audiogram, age, and their interaction were significantly associated with the likelihood for a non-HI hearing profile. In this study population, age and elapsed time since baseline audiogram were modestly associated with decreased hearing sensitivity and increased likelihood for a non-H1 hearing profile. Aircraft type, as determined from Air Force Specialty Code, was not associated with changes in hearing sensitivity by STS metric.Greenwell BM, Tvaryanas AP, Maupin GM. Risk factors for hearing decrement among U.S. Air Force aviation-related personnel. Aerosp Med Hum Perform. 2018; 89(2):80-86.

Dynamics of the hazard for distant metastases after ipsilateral breast tumor recurrence according to estrogen receptor status: An analysis of 2851 patients.

PubMed

Gennaro, Massimiliano; Di Cosimo, Serena; Ardoino, Ilaria; Veneroni, Silvia; Mariani, Luigi; Agresti, Roberto; Daidone, Maria Grazia; de Braud, Filippo; Apolone, Giovanni; Biganzoli, Elia; Demicheli, Romano

2018-05-14

Breast cancer (BC) patients with ipsilateral breast tumor recurrence (IBTR) are at high risk of developing distant metastases (DM). We aimed to evaluate the risk pattern of developing DM, with respect to the occurrence of IBTR, in a large series of patients homogeneously treated by conservative surgery (QUART) with a considerably long follow-up. Piecewise exponential model was used to investigate DM dynamics conditioning on known prognostic factors and IBTR occurrence as time dependent covariate. The model was extended to account for the timescale induced by IBTR, namely the time elapsed since IBTR to the endpoint. Among 2851 BCE patients receiving QUART, 209 were assessable for IBTR. After a median follow-up of 129 months, 588 patients presented DM (CCI = 27.3%) as first event and 92 (CCI = 48.8%) following IBTR. Primary tumor size and nodal status confirmed their prognostic value. The hazard for DM was early and high in Estrogen Receptor (ER) negative BC patients; while it was initially low but increases during follow-up in ER positive cases. Patients experiencing IBTR showed DM dynamic similar to that following primary tumor, with a sudden increased risk within 24 months from surgery, regardless the time elapsed since QUART. BC patients experiencing IBTR showed a sudden and sustained risk of DM following surgery. Our findings are consistent with the hypothesis that IBTR occurrence might act as a "time resector" for risk of DM, and provide a rationale for proper surveillance guidelines and systemic therapy for optimizing BC recurrence and appropriate choice of treatment. Copyright © 2018 Elsevier Ltd. All rights reserved.

Effect of lipstick on composite resin color at different application times

PubMed Central

GALVÃO, Avilmar Passos; JACQUES, Letícia Borges; DANTAS, Luciana; MATHIAS, Paula; MALLMANN, André

2010-01-01

Objectives The aim of this study was to evaluate the influence of the contact of two lipsticks, one with common fixer and one with ultra fixer, on the color of a composite resin immediately, 30 min and 24 h after photoactivation. Material and methods Ninety specimens were prepared with a composite resin, Filtek-Z350. Specimens were polished and divided into 9 groups (n=10) according to time elapsed after photoactivation (A- immediately; B- 30 min; C- 24 h) and the contact with lipstick (UF- lipstick with ultra fixer; F- lipstick with common fixer). The control group was represented by specimens that did not have any contact with lipstick (C- without lipstick). Color measurements of the specimens were carried out using a spectrophotometer (Easyshade - CIE L* a* b* system). For UF and F groups, the baseline color of the specimens was measured immediately before pigmentation and the lipsticks were applied dry after 1 hour. The excess lipstick was removed with absorbent paper and final color checking was performed, including the control group. Differences between the final and baseline color measurements were calculated and data were analyzed statistically by the Kruskal-Wallis test at 5%. Results The means between the differences of color values were: AUF: 16.0; AF: 12.4; AC: 1.07; BUF: 9.51; BF: 8.3; BC: 0.91; CUF: 17.7; CF: 12.41; CC: 0.82. Conclusion Groups where lipstick was applied showed greater staining than the control group at the three evaluation times. The lipstick with ultra fixer stained more than the lipstick with common fixer. Time elapsed between photoactivation and contact with lipstick had a similar influence on the groups that received lipstick application. PMID:21308286

Effect of lipstick on composite resin color at different application times.

PubMed

Galvão, Avilmar Passos; Jacques, Letícia Borges; Dantas, Luciana; Mathias, Paula; Mallmann, André

2010-12-01

The aim of this study was to evaluate the influence of the contact of two lipsticks, one with common fixer and one with ultra fixer, on the color of a composite resin immediately, 30 min and 24 h after photoactivation. Ninety specimens were prepared with a composite resin, Filtek-Z350. Specimens were polished and divided into 9 groups (n=10) according to time elapsed after photoactivation (A- immediately; B- 30 min; C- 24 h) and the contact with lipstick (UF- lipstick with ultra fixer; F- lipstick with common fixer). The control group was represented by specimens that did not have any contact with lipstick (C- without lipstick). Color measurements of the specimens were carried out using a spectrophotometer (Easyshade - CIE L* a* b* system). For UF and F groups, the baseline color of the specimens was measured immediately before pigmentation and the lipsticks were applied dry after 1 hour. The excess lipstick was removed with absorbent paper and final color checking was performed, including the control group. Differences between the final and baseline color measurements were calculated and data were analyzed statistically by the Kruskal-Wallis test at 5%. The means between the differences of color values were: AUF: 16.0; AF: 12.4; AC: 1.07; BUF: 9.51; BF: 8.3; BC: 0.91; CUF: 17.7; CF: 12.41; CC: 0.82. Groups where lipstick was applied showed greater staining than the control group at the three evaluation times. The lipstick with ultra fixer stained more than the lipstick with common fixer. Time elapsed between photoactivation and contact with lipstick had a similar influence on the groups that received lipstick application.

[Selective biopsy of the sentinel lymph node in patients with breast cancer and previous excisional biopsy: is there a change in the reliability of the technique according to time from surgery?].

PubMed

Sabaté-Llobera, A; Notta, P C; Benítez-Segura, A; López-Ojeda, A; Pernas-Simon, S; Boya-Román, M P; Bajén, M T

2015-01-01

To assess the influence of time on the reliability of sentinel lymph node biopsy (SLNB) in breast cancer patients with previous excisional biopsy (EB), analyzing both the sentinel lymph node detection and the lymph node recurrence rate. Thirty-six patients with cT1/T2 N0 breast cancer and previous EB of the lesion underwent a lymphoscintigraphy after subdermal periareolar administration of radiocolloid, the day before SLNB. Patients were classified into two groups, one including 12 patients with up to 29 days elapsed between EB and SLNB (group A), and another with the remaining 24 in which time between both procedures was of 30 days or more (group B). Scintigraphic and surgical detection of the sentinel lymph node, histological status of the sentinel lymph node and of the axillary lymph node dissection, if performed, and lymphatic recurrences during follow-up, were analyzed. Sentinel lymph node visualization at the lymphoscintigraphy and surgical detection were 100% in both groups. Histologically, three patients showed macrometastasis in the sentinel lymph node, one from group A and two from group B. None of the patients, not even those with malignancy of the sentinel lymph node, relapsed after a medium follow-up of 49.5 months (24-75). Time elapsed between EB and SLNB does not influence the reliability of this latter technique as long as a superficial injection of the radiopharmaceutical is performed, proving a very high detection rate of the sentinel lymph node without evidence of lymphatic relapse during follow-up. Copyright © 2014 Elsevier España, S.L.U. and SEMNIM. All rights reserved.

Influence of Bleaching Regimen and Time Elapsed on Microtensile Bond Strength of Resin Composite to Enamel

PubMed Central

Topcu, Fulya Toksoy; Erdemir, Ugur; Ozel, Emre; Tiryaki, Murat; Oktay, Elif Aybala; Yildiz, Esra

2017-01-01

Objectives: The aim of this study was to evaluate the effects of time elapsed since bleaching and different bleaching regimens on the microtensile bond strength of resin composite to enamel. Methodology: Forty flattened buccal enamel surfaces were divided into four groups: An unbleached (control) group and three bleaching groups. Control group specimens were not subjected to a bleaching regimen (Group 1), while those in the bleaching groups were bleached as follows: opalescence 10% (Group 2), whiteness perfect 16% (Group 3), and whiteness hydrogen peroxide 35% (Group 4). Thereafter, the bleached specimens were divided into three subgroups (n = 4 teeth each) for restoration according to predetermined posttreatment time intervals (immediately, 1 week, and 2 weeks). Bonded specimens were then sectioned and subjected to μTBS testing. The data were analyzed using Kruskal–Wallis and Mann–Whitney U-tests at α = 0.05. Results: There was a significant difference in the μTBS of the resin composite to enamel in groups that were bonded immediately after bleaching and in the control group (P < 0.05). Compared to the control group, the μTBS in Groups 2, 3, and 4 decreased significantly 1-week postbleaching (P < 0.05). No significant difference in μTBS was observed between the bleached and unbleached groups 2 weeks after treatment (P > 0.05). Conclusions: Adhesive restorative procedures could not be performed immediately or after 1 week irrespective of the type or concentration of bleaching system used. Composite restorations on bleached enamel surfaces should be performed after an interval of at least 2 weeks. PMID:29042734

Influence of Bleaching Regimen and Time Elapsed on Microtensile Bond Strength of Resin Composite to Enamel.

PubMed

Topcu, Fulya Toksoy; Erdemir, Ugur; Ozel, Emre; Tiryaki, Murat; Oktay, Elif Aybala; Yildiz, Esra

2017-01-01

The aim of this study was to evaluate the effects of time elapsed since bleaching and different bleaching regimens on the microtensile bond strength of resin composite to enamel. Forty flattened buccal enamel surfaces were divided into four groups: An unbleached (control) group and three bleaching groups. Control group specimens were not subjected to a bleaching regimen (Group 1), while those in the bleaching groups were bleached as follows: opalescence 10% (Group 2), whiteness perfect 16% (Group 3), and whiteness hydrogen peroxide 35% (Group 4). Thereafter, the bleached specimens were divided into three subgroups ( n = 4 teeth each) for restoration according to predetermined posttreatment time intervals (immediately, 1 week, and 2 weeks). Bonded specimens were then sectioned and subjected to μTBS testing. The data were analyzed using Kruskal-Wallis and Mann-Whitney U-tests at α = 0.05. There was a significant difference in the μTBS of the resin composite to enamel in groups that were bonded immediately after bleaching and in the control group ( P < 0.05). Compared to the control group, the μTBS in Groups 2, 3, and 4 decreased significantly 1-week postbleaching ( P < 0.05). No significant difference in μTBS was observed between the bleached and unbleached groups 2 weeks after treatment ( P > 0.05). Adhesive restorative procedures could not be performed immediately or after 1 week irrespective of the type or concentration of bleaching system used. Composite restorations on bleached enamel surfaces should be performed after an interval of at least 2 weeks.

Faster Synthesis of Beta-Diketonate Ternary Europium Complexes: Elapsed Times & Reaction Yields

PubMed Central

Lima, Nathalia B. D.; Silva, Anderson I. S.; Gerson, P. C.; Gonçalves, Simone M. C.; Simas, Alfredo M.

2015-01-01

β-diketonates are customary bidentate ligands in highly luminescent ternary europium complexes, such as Eu(β-diketonate)3(L)2, where L stands for a nonionic ligand. Usually, the syntheses of these complexes start by adding, to an europium salt such as EuCl3(H2O)6, three equivalents of β-diketonate ligands to form the complexes Eu(β-diketonate)3(H2O)2. The nonionic ligands are subsequently added to form the target complexes Eu(β-diketonate)3(L)2. However, the Eu(β-diketonate)3(H2O)2 intermediates are frequently both difficult and slow to purify by recrystallization, a step which usually takes a long time, varying from days to several weeks, depending on the chosen β-diketonate. In this article, we advance a novel synthetic technique which does not use Eu(β-diketonate)3(H2O)2 as an intermediate. Instead, we start by adding 4 equivalents of a monodentate nonionic ligand L straight to EuCl3(H2O)6 to form a new intermediate: EuCl3(L)4(H2O)n, with n being either 3 or 4. The advantage is that these intermediates can now be easily, quickly, and efficiently purified. The β-diketonates are then carefully added to this intermediate to form the target complexes Eu(β-diketonate)3(L)2. For the cases studied, the 20-day average elapsed time reduced to 10 days for the faster synthesis, together with an improvement in the overall yield from 42% to 69%. PMID:26710103

[Sudden cardiac death out of the hospital and early defibrillation].

PubMed

Marín-Huerta, E; Peinado, R; Asso, A; Loma, A; Villacastín, J P; Muñiz, J; Brugada, J

2000-06-01

Since most sudden cardiac death victims show neither symptoms before the event nor other signs or risk factors that would have identified them as a high risk population before their cardiac arrest, emergency out-of-hospital medical services must be improved in order to obtain a higher survival in these patients. Early defibrillation is an essential part of the chain of survival that also includes the early identification of the victim, activation of the emergency medical system, immediate arrival of trained personnel who can perform basic cardiopulmonary resuscitation and early initiation of advanced cardiac life support that would raise the survival rate for sudden cardiac arrest victims. Many studies have demonstrated the enormous importance of early defibrillation in patients with a cardiac arrest due to ventricular fibrillation. The most important predictor of survival in these individuals is the time that elapses until electric defibrillation, the longer the time to defbrillation the lower the number of patients who are eventually discharged. Multiple studies have demonstrated that automatic external defibrillation will reduce the time elapsed to defibrillation and thus improve survival. For these reason, public access defibrillation to allow the use of automatic external defibrillators by minimally trained members of the lay public, has received increasing interest on the part of a groving number of companies, cities or countries. The automatic external defibrillaton, as performed by a lay person is being investigated. The liberalization of its application, if is demonstrated to be effective, will need to be accompanied by legal measures to endorse it and appropriate health education, probably during secondary education.

Nutrients and sediment in frozen-ground runoff from no-till fields receiving liquid-dairy and solid-beef manures

USGS Publications Warehouse

Komiskey, Matthew J.; Stuntebeck, Todd D.; Frame, Dennis R.; Madison, Fred W.

2011-01-01

Nutrients and sediment in surface runoff from frozen agricultural fields were monitored within three small (16.0 ha [39.5 ac] or less), adjacent basins at a no-till farm in southwest Wisconsin during four winters from 2003 to 2004 through 2006 to 2007. Runoff depths and flow-weighted constituent concentrations were compared to determine the impacts of surface-applied liquid-dairy or solid-beef manure to frozen and/or snow-covered ground. Despite varying the manure type and the rate and timing of applications, runoff depths were not significantly different among basins within each winter period. Sediment losses were low (generally less than 22 kg ha−1 [20 lb ac−1] in any year) and any statistical differences in sediment concentrations among basins were not related to the presence or absence of manure or the amount of runoff. Concentrations and losses of total nitrogen and total phosphorus were significantly increased in basins that had either manure type applied less than one week preceding runoff. These increases occurred despite relatively low application rates. Lower concentrations and losses were measured in basins that had manure applied in fall and early winter and an extended period of time (months) had elapsed before the first runoff event. The highest mean, flow-weighted concentrations of total nitrogen (31.8 mg L−1) and total phosphorus (10.9 mg L−1) occurred in winter 2003 to 2004, when liquid-dairy manure was applied less than one week before runoff. On average, dissolved phosphorus accounted for over 80% of all phosphorus measured in runoff during frozen-ground periods. The data collected as part of this study add to the limited information on the quantity and quality of frozen-ground runoff at field edges, and the results highlight the importance of manure management decisions during frozen-ground periods to minimize nutrients lost in surface runoff.

Frey procedure for surgical management of chronic pancreatitis in children.

PubMed

Rollins, Michael D; Meyers, Rebecka L

2004-06-01

The authors adopted the Frey procedure for the surgical management of chronic pancreatitis after one of their patients had recurrent disease in the head of the gland after a longitudinal pancreaticojejunostomy (LPJ or modified Puestow procedure). This is the first description of its use in children. A retrospective chart review was performed of all children undergoing a drainage or resection procedure for chronic pancreatitis from 1995 to 2002. Eleven children (6 boys, 5 girls, ages 8 to 18 years) underwent either the LPJ (3) or Frey (8) procedure. Etiologies included: idiopathic (5), familial (2), congenital anomaly of the major papilla (1), pancreatic head mass (1), short bowel syndrome (1), and pancreatic divisum (1). Before surgical therapy, patients had been symptomatic 2.3 years (range, 1 month to 6 years) and had been hospitalized for pancreatitis 4 times (range, 1 to 10). Four patients did not respond to endoscopic stenting, and 5 had a pancreatic pseudocyst. Patients were followed up in clinic an average of 2.5 years, with total time elapsed since surgery averaging 4.6 years. Eight of 11 patients experienced excellent or good results subsequent to surgical intervention. The Frey procedure is effective for children who have not responded to conservative management of chronic pancreatitis and may prevent recurrent disease in the head of the gland.

Timing of late Holocene surface rupture of the Wairau Fault, Marlborough, New Zealand

USGS Publications Warehouse

Zachariasen, J.; Berryman, K.; Langridge, Rob; Prentice, C.; Rymer, M.; Stirling, M.; Villamor, P.

2006-01-01

Three trenches excavated across the central portion of the right-lateral strike-slip Wairau Fault in South Island, New Zealand, exposed a complex set of fault strands that have displaced a sequence of late Holocene alluvial and colluvial deposits. Abundant charcoal fragments provide age control for various stratigraphic horizons dating back to c. 5610 yr ago. Faulting relations from the Wadsworth trench show that the most recent surface rupture event occurred at least 1290 yr and at most 2740 yr ago. Drowned trees in landslide-dammed Lake Chalice, in combination with charcoal from the base of an unfaulted colluvial wedge at Wadsworth trench, suggest a narrower time bracket for this event of 1811-2301 cal. yr BP. The penultimate faulting event occurred between c. 2370 and 3380 yr, and possibly near 2680 ?? 60 cal. yr BP, when data from both the Wadsworth and Dillon trenches are combined. Two older events have been recognised from Dillon trench but remain poorly dated. A probable elapsed time of at least 1811 yr since the last surface rupture, and an average slip rate estimate for the Wairau Fault of 3-5 mm/yr, suggests that at least 5.4 m and up to 11.5 m of elastic shear strain has accumulated since the last rupture. This is near to or greater than the single-event displacement estimates of 5-7 m. The average recurrence interval for surface rupture of the fault determined from the trench data is 1150-1400 yr. Although the uncertainties in the timing of faulting events and variability in inter-event times remain high, the time elapsed since the last event is in the order of 1-2 times the average recurrence interval, implying that the Wairau Fault is near the end of its interseismic period. ?? The Royal Society of New Zealand 2006.

Functional treatment after surgical repair for acute lateral ligament disruption of the ankle in athletes.

PubMed

Takao, Masato; Miyamoto, Wataru; Matsui, Kentaro; Sasahara, Jun; Matsushita, Takashi

2012-02-01

There have been several reports showing 20% to 40% failure after nonoperative functional treatment for acute lateral ligament disruption of the ankle. Functional treatment after primary surgical repair has the advantage of decreasing the failure rate in comparison with functional treatment alone. Cohort study; Level of evidence, 3. A total of 132 feet of 132 patients were included in this study. Of these, 78 patients were treated with functional treatment alone (group F), and the remaining 54 patients were treated with functional treatment after primary surgical repair (group RF). The clinical results were evaluated using the Japanese Society for Surgery of the Foot Ankle-Hindfoot scale (JSSF) score, measuring the talar tilt angle and the anterior displacement of the talus in stress radiography, and noting the elapsed time between the injury and the return to the full athletic activity with no external supports. The mean JSSF scores at 2 years after injury were 95.6 ± 5.0 points in group F and 97.5 ± 2.6 points in group RF (P = .0669). The differences of the talar tilt angles compared with the contralateral side and displacement of the talus on stress radiography at 2 years after injury were 1.1° ± 1.5° and 3.6 ± 1.6 mm in group F, and 0.8° ± 0.9° and 3.2 ± 0.8 mm in group RF, respectively (P = .4093, .1883). In group F, 8 cases showed fair to poor results, with JSSF scores below 80 points and instability at 2 years after injury. In group RF, 9 cases (9.4%) showed dorsum foot pain along the superficial peroneal nerve, which disappeared within a month. The time elapsed between the injury and the patient's return to full athletic activity without any external supports was 16.0 ± 5.6 weeks in group F and 10.1 ± 1.8 weeks in group RF (P < .0001). Nonoperative functional treatment alone and functional treatment after primary surgical repair showed similar overall results after acute lateral ankle sprain, but functional treatment alone had an approximately 10% failure rate and a slower return to full athletic activity. The authors recommend that treatment be tailored to suit each individual athlete.

Flight Test of a 30-Foot Nominal-Diameter Disk-Gap-Band Parachute Deployed at Mach 1.56 and Dynamic Pressure of 11.4 Pounds per Square Foot

NASA Technical Reports Server (NTRS)

Eckstrom, Clinton V.; Preisser, John S.

1967-01-01

A 30-foot (9.1 meter) nominal-diameter disk-gap-band parachute (reference area 707 sq ft (65.7 m(exp 2)) was flight tested with a 200-pound (90.7 kg) instrumented payload as part of the NASA Planetary Entry Parachute Program. A deployment mortar ejected the test parachute when the payload was at a Mach number of 1.56 and a dynamic pressure of 11.4 lb/sq ft (546 newtons per m 2 ) at an altitude of 127,500 feet (38.86 km). The parachute reached suspension line stretch in 0.37 second resulting in a snatch force loading of 1270 pounds (5650 N). Canopy inflation began 0.10 second after line stretch. A delay in the opening process occurred and was apparently due to a momentary interference of the glass-fiber shroud used in packing the parachute bag in the mortar. Continuous canopy inflation began 0.73 second after initiation of deployment and 0.21 second later full inflation was attained for a total elapsed time from mortar fire of 0.94 second. The maximum opening load of 3915 pounds (17,400 newtons) occurred at the time the canopy was first fully opened. The parachute exhibited an average drag coefficient of 0.52 during the deceleration period and pitch-yaw oscillations of the canopy were less than 5 degrees. During the steady-state descent portion of the test period, the average effective drag coefficient was about 0.47 (based on vertical descent velocity and total system weight).

Health-related quality of life in patients with spinocerebellar ataxia.

PubMed

Sánchez-López, C R; Perestelo-Pérez, L; Escobar, A; López-Bastida, J; Serrano-Aguilar, P

2017-04-01

The progressive deterioration of patients with spinocerebellar ataxia (SCA) has a major impact on their health-related quality of life (HRQOL). This study evaluates HRQOL in a sample of patients diagnosed with SCA and aims to estimate the predictive ability of a set of sociodemographic variables for the different dimensions of the General Health Questionnaire. A total of 80 patients diagnosed with SCA were assessed using a sociodemographic questionnaire and the SF-36 General Health Questionnaire. The sociodemographic variables studied were sex, age, presence of a carer, employment status, and time elapsed from diagnosis of the disease. The 8 subscales of the SF-36 show positive and significant correlations to one another. Mean scores obtained on each SF-36 subscale differ between women and men, although this difference is significant only on the general health subscale, with men scoring higher than women. We found significant age differences on the vitality and social function subscales, with higher scores among younger patients (< 34 years). The variable 'presence of a carer' accounts for most of the total variance of the questionnaire. The SF-36 is a valid and useful instrument for evaluating HRQOL in patients diagnosed with SCA. Presence of a carer seems to be a determinant of self-perceived quality of life in these patients. Copyright © 2015 Sociedad Española de Neurología. Publicado por Elsevier España, S.L.U. All rights reserved.

An elevated neutrophil-lymphocyte ratio is associated with adverse outcomes following single time-point paracetamol (acetaminophen) overdose: a time-course analysis.

PubMed

Craig, Darren G; Kitto, Laura; Zafar, Sara; Reid, Thomas W D J; Martin, Kirsty G; Davidson, Janice S; Hayes, Peter C; Simpson, Kenneth J

2014-09-01

The innate immune system is profoundly dysregulated in paracetamol (acetaminophen)-induced liver injury. The neutrophil-lymphocyte ratio (NLR) is a simple bedside index with prognostic value in a number of inflammatory conditions. To evaluate the prognostic accuracy of the NLR in patients with significant liver injury following single time-point and staggered paracetamol overdoses. Time-course analysis of 100 single time-point and 50 staggered paracetamol overdoses admitted to a tertiary liver centre. Timed laboratory samples were correlated with time elapsed after overdose or admission, respectively, and the NLR was calculated. A total of 49/100 single time-point patients developed hepatic encephalopathy (HE). Median NLRs were higher at both 72 (P=0.0047) and 96 h after overdose (P=0.0041) in single time-point patients who died or were transplanted. Maximum NLR values by 96 h were associated with increasing HE grade (P=0.0005). An NLR of more than 16.7 during the first 96 h following overdose was independently associated with the development of HE [odds ratio 5.65 (95% confidence interval 1.67-19.13), P=0.005]. Maximum NLR values by 96 h were strongly associated with the requirement for intracranial pressure monitoring (P<0.0001), renal replacement therapy (P=0.0002) and inotropic support (P=0.0005). In contrast, in the staggered overdose cohort, the NLR was not associated with adverse outcomes or death/transplantation either at admission or subsequently. The NLR is a simple test which is strongly associated with adverse outcomes following single time-point, but not staggered, paracetamol overdoses. Future studies should assess the value of incorporating the NLR into existing prognostic and triage indices of single time-point paracetamol overdose.

KSC-07pd3172

NASA Image and Video Library

2007-11-07

KENNEDY SPACE CENTER, FLA. -- Associate Administrator for NASA Space Operations William Gerstenmaier and Shuttle Program Manager Wayne Hale examine the thermal protection system on the wing of space shuttle Discovery after its landing at NASA's Kennedy Space Center. Discovery completed the 15-day mission STS-120, with an on-time landing at 1:01:16 p.m. Wheel stop was at 1:02:07 p.m. Mission elapsed time was 15 days, 2 hours, 24 minutes and 2 seconds. Mission STS-120 continued the construction of the station with the installation of the Harmony Node 2 module and the relocation of the P6 truss. Photo credit: NASA//Kim Shiflett

KSC-07pd3171

NASA Image and Video Library

2007-11-07

KENNEDY SPACE CENTER, FLA. -- Shuttle Program Manager Wayne Hale points to the left wing of space shuttle Discovery after its landing at NASA's Kennedy Space Center. To the left is Associate Administrator for NASA Space Operations William Gerstenmaier. Discovery completed the 15-day mission STS-120, with an on-time landing at 1:01:16 p.m. Wheel stop was at 1:02:07 p.m. Mission elapsed time was 15 days, 2 hours, 24 minutes and 2 seconds. Mission STS-120 continued the construction of the station with the installation of the Harmony Node 2 module and the relocation of the P6 truss. Photo credit: NASA/Kim Shiflett

KSC-06pd1576

NASA Image and Video Library

2006-07-17

KENNEDY SPACE CENTER, FLA. - The STS-121 crew gets a close look at the underside of the orbiter Discovery after landing. Seen are (from left) Mission Specialist Stephanie Wilson, Commander Steven Lindsey and Mission Specialists Lisa Nowak and Michael Fossum. The post-flight walk-around is a tradition. Discovery's smooth and perfect landing was on time at 9:14 a.m. EDT on Runway 15 of NASA's Shuttle Landing Facility after traveling 5.3 million miles on 202 orbits. Mission elapsed time was 12 days, 18 hours, 37 minutes and 54 seconds. The landing is the 62nd at Kennedy Space Center and the 32nd for Discovery. Photo credit: NASA/Kim Shiflett

Research on techniques for laser ranging to optical corner reflectors on the moon. Research on laser techniques and single photo-electron detection and timing

NASA Technical Reports Server (NTRS)

Alley, C. O.

1976-01-01

Experimental studies using a pulsed LED, Cerenkov source, and a 100 ps laser were made of various photomultipliers and discriminator combinations. In addition, a new type of neodymium-YAG frequency doubled laser was used as the basis for the development of a stable, short pulse, high repetition rate laser system. This laser was then used in conjunction with atomic clocks to study the effect of gravitational potential on elapsed time. Avenues to promote the development of international cooperation in the area of lunar laser ranging were also explored.

Evolution Of The Concept Of Dimension

NASA Astrophysics Data System (ADS)

Journeau, Philippe F.

2007-04-01

Concepts of time elapsing `in' a space measuring the real emerge over the centuries. But Kant refutes absolute time and defines it, with space, as forms reacting to Newtonian mechanics. Einstein and Minkowski open a 20th century where time is a dimension, a substratum of reality `with' space rather than `in' it. Kaluza-Klein and String theories then develop a trend of additional spatial dimensions while de Broglie and Bohm open the possiblity that form, to begin with wave, be a reality together `with' a space-time particle. Other recent theories, such as spin networks, causal sets and twistor theory, even head to the idea of other "systems of dimensions." On the basis of such progresses and recent experiments the paper then considers a background independent fourfold time-form-action-space system of dimensions.

Comprehensive treatment for gas gangrene of the limbs in earthquakes.

PubMed

Wang, Yue; Lu, Bo; Hao, Peng; Yan, Meng-ning; Dai, Ke-rong

2013-10-01

Mortality rates for patients with gas gangrene from trauma or surgery are as high as 25%, but they increase to 50%-80% for patients injured in natural hazards. Early diagnosis and treatment are essential for these patients. We retrospectively analyzed the clinical characteristics and therapeutic results of 19 patients with gas gangrene of the limbs, who were injured in the May 2008 earthquake in the Wenchuan district of China's Sichuan province and treated in our hospital, to seek how to best diagnose and treat earthquake-induced gas gangrene. Of 226 patients with limbs open injuries sustained during the earthquake, 53 patients underwent smear analysis of wound exudates and gas gangrene was diagnosed in 19 patients. The average elapsed time from injury to arrival at the hospital was 72 hours, from injury to definitive diagnosis was 4.3 days, and from diagnosis to conversion of negative findings on wound smear analysis to positive findings was 12.7 days. Anaerobic cultures were also obtained before wound closure. The average elapsed time from completion of surgery to recovery of normal vital signs was 6.3 days. Of the 19 patients, 16 were treated with open amputation, two with closed amputation, and 1 with successful limb salvage; 18 patients were successfully treated and one died. In earthquakes, rapid, accurate screening and isolation are essential to successful treatment of gas gangrene and helpful in preventing nosocomial diffusion. Early and thorough debridement, open amputation, and active supportive treatment can produce satisfactory therapeutic results.

[Health care circuit for patients with soft tissue sarcomas of the extremities. A tortuous and slow road to referral units].

PubMed

Ramos-Pascua, L R; Sánchez-Herráez, S; Casas-Ramos, P; Izquierdo-García, F J; Maderuelo-Fernández, J A

2014-01-01

To analyse the waiting periods elapsed since soft tissue sarcomas become symptomatic until their specific treatment in our unit, and to determine new strategies for the improvement of referral circuits. This is an ambispective observational study of a cohort of 61 patients, with previously untreated soft tissue sarcomas, obtained from our Musculoskeletal Tumors Database. Several variables related to the patient, tumour, and health care circuit were analysed, as well as the different periods between the initial symptoms of the disease and the first consultation in our unit. The significance level was α=0.05. The mean size of the sarcomas was 11.3 cm. Thirty-six patients (59%) followed the usual circuit of the National Health System in Spain. The time elapsed since the disease became symptomatic until the first medical consultation was greater than 9.5 months, and nearly another 8.5 months to the consultation in our specific unit. Statistically significant relationships were found between the independent and dependent variables. The study shows that the care of patients with soft tissue sarcomas in our environment is far away from the times of care in our neighbouring countries. It is essential to make the population and health professionals aware of this disease, as well as to remember that there is a referral circuit that must be used. Copyright © 2013 SECOT. Published by Elsevier Espana. All rights reserved.

[Concentration of pro-inflammatory interleukins in cervical secretions of women with PROM and in the umbilical cord blood of their newborns].

PubMed

Skrzypczak, Jana; Wirstlein, Przemysław K; Wróbel, Magdalena; Mikołajczyk, Mateusz

2015-06-01

The aim of the study was to analyze the levels of pro-inflammatory interleukins in cervical secretions of women with PROM, depending on Ureaplasma spp. infection and the time elapsed since the rupture of the membranes, and to correlate their concentration in cervical secretions and in cord blood of the newborns. The study included 30 women with PROM between 24 and 33+6 weeks of gestation. Cervical swabs from women with confirmed rupture of membranes taken at certain intervals and umbilical cord blood of their newborns constituted the study material. Cervical secretions were evaluated microbiologically and by the PCR method. Concentrations of IL-6, IL-19, IL-10 and TNF-α were analyzed by ELISA. Ureaplasma spp. were the most frequently isolated microorganisms in cervical secretions of women with PROM. Secretion of interleukins in the cervix was not influenced by time elapsed since the PROM. Comparison of interleukin levels in cord blood of newborns born to mothers with and without Ureaplasma spp infection revealed significantly higher levels of IL-6 in the case of Ureaplasma spp. A positive correlation between IL-6 and TNF-α levels in cervical secretions and in cord blood of mothers with PROM and Ureaplasma spp. was detected. 1. Cervical culture method appears to be sufficient for detecting Ureaplasma spp. 2. Pro-inflammatory interleukins, especially IL-6, obtained by non-invasive methods can be used to predict fetal inflammatory response.

A 12-Year Retrospective Study of Avulsion Cases in a Public Brazilian Dental Trauma Service.

PubMed

Mesquita, Gabriela Campos; Soares, Priscilla Barbosa Ferreira; Moura, Camilla Christian Gomes; Roscoe, Marina Guimarães; Paiva, Saul Martins; Soares, Carlos José

2017-01-01

This study assessed the epidemiological characteristics and management of the permanent teeth avulsion cases attended in a Brazilian dental trauma service from December 2005 to August 2016. A retrospective study was conducted of case records of 93 patients involving 139 avulsed teeth. Data included sex, age, trauma etiology, location of the accident, number and position of avulsed teeth, and presence and type of associated traumatic lesions. Management of the avulsed teeth was addressed as: time elapsed until teeth were retrieved from the accident's location; teeth's cleaning method and storage media; time elapsed until seeking treatment and replantation. The majority of the patients were children from 6-10 (31.2%) and 11-15 years old (26.9%). Male patients were more affected than female. Bicycle accident was the main etiological factor (31.2%). In 56 (60.2%) cases, traumatic lesions to neighboring teeth were present. In 55 (59.1%) cases, lesions to adjacent soft tissues were reported. In 82 (88.2%) cases, patients requested treatment at the same day of the accident. Sixty-four teeth (46.0%) were immediately retrieved and 28 (20.1%) were not found. Forty-two teeth (30.2%) were kept dry. Only one tooth (0.7%) was immediately replanted at the accident's site, while 51 teeth (36.7%) were not replanted. Numerous avulsed teeth were inappropriately managed and immediate replantation was not frequent. Public policies must be created to raise awareness towards the particularities of avulsion cases.

Integrating EarthScope Data to Constrain the Long-Term Effects of Tectonism on Continental Lithosphere

NASA Astrophysics Data System (ADS)

Porter, R. C.; van der Lee, S.

2017-12-01

One of the most significant products of the EarthScope experiment has been the development of new seismic tomography models that take advantage of the consistent station design, regular 70-km station spacing, and wide aperture of the EarthScope Transportable Array (TA) network. These models have led to the discovery and interpretation of additional compositional, thermal, and density anomalies throughout the continental US, especially within tectonically stable regions. The goal of this work is use data from the EarthScope experiment to better elucidate the temporal relationship between tectonic activity and seismic velocities. To accomplish this, we compile several upper-mantle seismic velocity models from the Incorporated Research Institute for Seismology (IRIS) Earth Model Collaboration (EMC) and compare these to a tectonic age model we compiled using geochemical ages from the Interdisciplinary Earth Data Alliance: EarthChem Database. Results from this work confirms quantitatively that the time elapsed since the most recent tectonic event is a dominant influence on seismic velocities within the upper mantle across North America. To further understand this relationship, we apply mineral-physics models for peridotite to estimate upper-mantle temperatures for the continental US from tomographically imaged shear velocities. This work shows that the relationship between the estimated temperatures and the time elapsed since the most recent tectonic event is broadly consistent with plate cooling models, yet shows intriguing scatter. Ultimately, this work constrains the long-term thermal evolution of continental mantle lithosphere.

Serum concentrations of brain-derived neurotrophic factor in patients diagnosed with gender dysphoria undergoing sex reassignment surgery.

PubMed

Schneider, Maiko A; Andreazza, Tahiana; Fontanari, Anna Martha V; Costa, Angelo B; Silva, Dhiordan C da; Aguiar, Bianca W de; Massuda, Raffael; Pedrini, Mariana; Gama, Clarissa S; Schwarz, Karine; Kauer-Sant'Anna, Marcia; Lobato, Maria Ines R

2017-01-01

Transsexualism (ICD-10) is a condition characterized by a strong and persistent dissociation with one's assigned gender. Sex reassignment surgery (SRS) and hormone therapy provide a means of allowing transsexual individuals to feel more congruent with their gender and have played a major role in treatment over the past 70 years. Brain-derived neurotrophic factor (BDNF) appears to play a key role in recovery from acute surgical trauma and environmentally mediated vulnerability to psychopathology. We hypothesize that BDNF may be a biomarker of alleviation of gender incongruence suffering. To measure preoperative and postoperative serum BDNF levels in transsexual individuals as a biomarker of alleviation of stress related to gender incongruence after SRS. Thirty-two male-to-female transsexual people who underwent both surgery and hormonal treatment were selected from our initial sample. BDNF serum levels were assessed before and after SRS with sandwich enzyme linked immunosorbent assay (ELISA). The time elapsed between the pre-SRS and post-SRS blood collections was also measured. No significant difference was found in pre-SRS or post-SRS BDNF levels or with relation to the time elapsed after SRS when BDNF levels were measured. Alleviation of the suffering related to gender incongruence after SRS cannot be assessed by BDNF alone. Surgical solutions may not provide a quick fix for psychological distress associated with transsexualism and SRS may serve as one step toward, rather than as the conclusion of, construction of a person's gender identity.

Modelling the time at which overcrowding and feed interruption emerge on the swine premises under movement restrictions during a classical swine fever outbreak.

PubMed

Weng, H Y; Yadav, S; Olynk Widmar, N J; Croney, C; Ash, M; Cooper, M

2017-03-01

A stochastic risk model was developed to estimate the time elapsed before overcrowding (TOC) or feed interruption (TFI) emerged on the swine premises under movement restrictions during a classical swine fever (CSF) outbreak in Indiana, USA. Nursery (19 to 65 days of age) and grow-to-finish (40 to 165 days of age) pork production operations were modelled separately. Overcrowding was defined as the total weight of pigs on premises exceeding 100% to 115% of the maximum capacity of the premises, which was computed as the total weight of the pigs at harvest/transition age. Algorithms were developed to estimate age-specific weight of the pigs on premises and to compare the daily total weight of the pigs with the threshold weight defining overcrowding to flag the time when the total weight exceeded the threshold (i.e. when overcrowding occurred). To estimate TFI, an algorithm was constructed to model a swine producer's decision to discontinue feed supply by incorporating the assumptions that a longer estimated epidemic duration, a longer time interval between the age of pigs at the onset of the outbreak and the harvest/transition age, or a longer progression of an ongoing outbreak would increase the probability of a producer's decision to discontinue the feed supply. Adverse animal welfare conditions were modelled to emerge shortly after an interruption of feed supply. Simulations were run with 100 000 iterations each for a 365-day period. Overcrowding occurred in all simulated iterations, and feed interruption occurred in 30% of the iterations. The median (5th and 95th percentiles) TOC was 24 days (10, 43) in nursery operations and 78 days (26, 134) in grow-to-finish operations. Most feed interruptions, if they emerged, occurred within 15 days of an outbreak. The median (5th and 95th percentiles) time at which either overcrowding or feed interruption emerged was 19 days (4, 42) in nursery and 57 days (4, 130) in grow-to-finish operations. The study findings suggest that overcrowding and feed interruption could emerge early during a CSF outbreak among swine premises under movement restrictions. The outputs derived from the risk model could be used to estimate and evaluate associated mitigation strategies for alleviating adverse animal welfare conditions resulting from movement restrictions.

Administration Time for the First Dose of Antimicrobials in Episodes of Fever and Neutropenia in Children With Cancer.

PubMed

De la Maza, Verónica; Simian, Daniela; Castro, Magdalena; Torres, Juan Pablo; Lucero, Yudeth; Sepúlveda, Fanny; Mazquiaran, Soraya; Salazar, Carolina; Segovia, Lorena; Santolaya, Maria Elena

2015-10-01

Early administration of antimicrobial (AM) is relevant in children with cancer, fever and neutropenia (FN). The recommendation is to administer the first dose of AM within the first hour of hospital admission. Our aims were to determine the time from the moment that a child with FN is admitted to the hospital until they receive their first dose of AM and to determine the association with clinical outcomes. This prospective, multicenter study evaluated the time elapsed from the admission to the first dose of AM, comparing this variable by admitting hospital and presentation location (Emergency Department/Oncology Units) and evaluating the clinical outcomes by the following variables: days of fever, days of hospitalization, hypotension, transfer to intensive care unit, sepsis and mortality. A total of 226 children with 388 episodes of FN were enrolled from 5 hospitals (July 2012-April 2014). The median time between hospital admission and administration of the first dose of AM was 132 minutes (interquartile range: 60-246 minutes). The median time to AM administration was significantly different between hospitals (70 vs. 200 minutes, P < 0.0001) and between presentation locations (Emergency Department vs. Oncology Units, median: 200 vs. 100 minutes, P < 0.0001). Twenty-five percentage of children received AM within 1 hour of admission. The administration of AM after 60 minutes was not associated with worse outcomes. Time to AM administration was longer than the recommendation. The findings described provide an opportunity to identify gaps and implement programs aimed at improving the equity and excellence of care in children with cancer and FN.

Oral impacts on quality of life and problem-oriented attendance among South East London adults.

PubMed

Gaewkhiew, Piyada; Bernabé, Eduardo; Gallagher, Jennifer E; Klass, Charlotte; Delgado-Angulo, Elsa K

2017-04-26

Dental care seeking behaviour is often driven by symptoms. The value of oral health related quality of life (OHRQoL) measures to predict utilisation of dental services is unknown. This study aims to explore the association between OHRQoL and problem-oriented dental attendance among adults. We analysed cross-sectional data for 705 adults, aged 16 years and above, living in three boroughs of Inner South East London. Data were collected during structured interviews at home. The short form of the Oral Health Impact Profile (OHIP-14) was used to assess the frequency of oral impacts on daily life in the last year. Problem-oriented attendance was defined based on time elapsed since last visit (last 6 months) and reason for that visit (trouble with teeth). The association between OHIP-14 (total and domain) scores and problem-oriented attendance was tested in logistic regression models adjusting for participants' sociodemographic characteristics. Problem-oriented attenders had a higher OHIP-14 total score than regular attenders (6.73 and 3.73, respectively). In regression models, there was a positive association between OHIP-14 total score and problem-oriented attendance. The odds of visiting the dentist for trouble with teeth were 1.07 greater (95% Confidence Interval: 1.04-1.10) per unit increase in the OHIP-14 total score, after adjustment for participants' sociodemographic characteristics. In subsequent analysis by OHIP-14 domains, greater scores in all domains but handicap were significantly associated with problem-oriented attendance. This study shows that oral impacts on quality of life are associated with recent problem-oriented dental attendance among London adults. Six of the seven domains in the OHIP-14 questionnaire were also associated with dental visits for trouble with teeth.

Evaluation of land use and water quality in an agricultural watershed in the USA indicates multiple sources of bacterial impairment.

PubMed

Wittman, Jacob; Weckwerth, Andrew; Weiss, Chelsea; Heyer, Sharon; Seibert, Jacob; Kuennen, Ben; Ingels, Chad; Seigley, Lynette; Larsen, Kirk; Enos-Berlage, Jodi

2013-12-01

Pathogens are the number one cause of impairments of assessed rivers and streams in the USA and pose a significant human health hazard. The Dry Run Creek Watershed in Northeast Iowa has been designated as impaired by the State of Iowa because of high levels of Escherichia coli bacteria. To investigate the nature of this impairment, land use and stream bank assessments were coupled with comprehensive water quality monitoring. Physical, chemical, and biological parameters were measured at 13 different sites in the watershed, including pH, temperature, conductivity, dissolved oxygen, turbidity, total Kjeldahl nitrogen, ammonia-N, nitrate + nitrite-N, total phosphorus, and E. coli. In addition, benthic macroinvertebrate communities were analyzed at seven sites, and optical brightener tests were performed late in the season. Results identified segments of the watershed that were more prominent contributors of E. coli, and correlations were observed between levels of E. coli and several chemical parameters, including ammonia-N, total Kjeldahl nitrogen, and total phosphorus. Interestingly, distinct sites emerged as more prominent contributors of these elements during rain vs. non-rain events, suggesting different types of sources. Both the amount of rainfall and the time elapsed between the rain event and the sampling influenced E. coli levels during wet weather conditions. Nitrate + nitrite-N displayed a unique response to rain events compared with the other parameters, suggesting a different delivery route. Analyses of benthic macroinvertebrate communities were consistent with pollution trends. Collectively, these data suggest distinct agriculturally related E. coli contributions, as well as specific areas and practices for water quality improvement strategies. This study can serve as a resource for evaluating agricultural watersheds that are impaired for bacteria.

Adherence to AHA Guidelines When Adapted for Augmented Reality Glasses for Assisted Pediatric Cardiopulmonary Resuscitation: A Randomized Controlled Trial.

PubMed

Siebert, Johan N; Ehrler, Frederic; Gervaix, Alain; Haddad, Kevin; Lacroix, Laurence; Schrurs, Philippe; Sahin, Ayhan; Lovis, Christian; Manzano, Sergio

2017-05-29

The American Heart Association (AHA) guidelines for cardiopulmonary resuscitation (CPR) are nowadays recognized as the world's most authoritative resuscitation guidelines. Adherence to these guidelines optimizes the management of critically ill patients and increases their chances of survival after cardiac arrest. Despite their availability, suboptimal quality of CPR is still common. Currently, the median hospital survival rate after pediatric in-hospital cardiac arrest is 36%, whereas it falls below 10% for out-of-hospital cardiac arrest. Among emerging information technologies and devices able to support caregivers during resuscitation and increase adherence to AHA guidelines, augmented reality (AR) glasses have not yet been assessed. In order to assess their potential, we adapted AHA Pediatric Advanced Life Support (PALS) guidelines for AR glasses. The study aimed to determine whether adapting AHA guidelines for AR glasses increased adherence by reducing deviation and time to initiation of critical life-saving maneuvers during pediatric CPR when compared with the use of PALS pocket reference cards. We conducted a randomized controlled trial with two parallel groups of voluntary pediatric residents, comparing AR glasses to PALS pocket reference cards during a simulation-based pediatric cardiac arrest scenario-pulseless ventricular tachycardia (pVT). The primary outcome was the elapsed time in seconds in each allocation group, from onset of pVT to the first defibrillation attempt. Secondary outcomes were time elapsed to (1) initiation of chest compression, (2) subsequent defibrillation attempts, and (3) administration of drugs, as well as the time intervals between defibrillation attempts and drug doses, shock doses, and number of shocks. All these outcomes were assessed for deviation from AHA guidelines. Twenty residents were randomized into 2 groups. Time to first defibrillation attempt (mean: 146 s) and adherence to AHA guidelines in terms of time to other critical resuscitation endpoints and drug dose delivery were not improved using AR glasses. However, errors and deviations were significantly reduced in terms of defibrillation doses when compared with the use of the PALS pocket reference cards. In a total of 40 defibrillation attempts, residents not wearing AR glasses used wrong doses in 65% (26/40) of cases, including 21 shock overdoses >100 J, for a cumulative defibrillation dose of 18.7 Joules per kg. These errors were reduced by 53% (21/40, P<.001) and cumulative defibrillation dose by 37% (5.14/14, P=.001) with AR glasses. AR glasses did not decrease time to first defibrillation attempt and other critical resuscitation endpoints when compared with PALS pocket cards. However, they improved adherence and performance among residents in terms of administering the defibrillation doses set by AHA. ©Johan N Siebert, Frederic Ehrler, Alain Gervaix, Kevin Haddad, Laurence Lacroix, Philippe Schrurs, Ayhan Sahin, Christian Lovis, Sergio Manzano. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 29.05.2017.

Hydroclimatic influences on non-stationary transit time distributions in a boreal headwater catchment

NASA Astrophysics Data System (ADS)

Peralta-Tapia, A.; Soulsby, C.; Tetzlaff, D.; Sponseller, R.; Bishop, K.; Laudon, H.

2016-12-01

Understanding how water moves through catchments - from the time it enters as precipitation to when it exits via streamflow - is of fundamental importance to understanding hydrological and biogeochemical processes. A basic descriptor of this routing is the Transit Time Distribution (TTD) which is derived from the input-output behavior of conservative tracers, the mean of which represents the average time elapsed between water molecules entering and exiting a flow system. In recent decades, many transit time studies have been conducted, but few of these have focused on snow-dominated catchments. We assembled a 10-year time series of isotopic data (δ18O and δ2H) for precipitation and stream water to estimate the characteristics of the transit time distribution in a boreal catchment in northern Sweden. We applied lumped parameter models using a gamma distribution to calculate the Mean Transit Time (MTT) of water over the entire period of record and to evaluate how inter-annual differences in transit times relate to hydroclimatic variability. The best fit MTT for the complete 10-year period was 650 days (Nash-Sutcliff Efficiency = 0.65), while the best fit inter-annual MTT ranged from 300 days up to 1200 days. Whilst there was a weak negative correlation between mean annual total precipitation and the annual MTT, this relationship was stronger (r2 = 0.53, p = 0.02) for the annual rain water input. This strong connection between the MTT and annual rainfall, rather than snowmelt, has strong implications for understanding future hydrological and biogeochemical processes in boreal regions, given that predicted warmer winters would translate into a greater proportion of precipitation falling as rain and thus shorter MTT in catchments. Such a change could have direct implications for the export of solutes and pollutants.

The Effect of Preoperative Ketorolac on WBC Response and Pain in Laparoscopic Surgery for Endometriosis

PubMed Central

2005-01-01

Surgical stress causes changes in the composition of white blood cells (WBCs). Ketorolac is believed to have analgesic effects and to reduce the stress response and may therefore improve postoperative outcomes. The aim of this study was to assess the effect of preoperative ketorolac on the WBC subsets in patients who had laparoscopic surgery for endometriosis. Fifty patients who had laparoscopic surgery for endometriosis were randomly assigned to one of two groups: the ketorolac group (n = 25) received ketorolac 0.5 mg/kg before the induction of anesthesia, and the control group (n = 25) received saline. White cell count, differential, and pathology studies were done immediately after surgery, on postoperative day 1, and on postoperative day 3. We compared the baseline values within and between the two groups. We also assessed postoperative pain and side effects. The time that elapsed before the first patient request for analgesia, total meperidine dose and VAS (Visual Analog Scale) for postoperative pain were significantly lower in the ketorolac group than in the control group. Compared to the pre- surgical values, there was an increase in total WBC count and percentage of neutrophils, but a decrease in percentages of lymphocytes, monocytes, eosinophils, basophils, and leucocytes. Total WBC count, neutrophils, monocytes, eosinophils and leucocytes showed significant differences between the two groups. The incidences of postoperative side effects, such as nausea, dizziness, headache, and shoulder pain were not different between the groups. Preoperative ketorolac reduced postoperative pain and influenced the WBC response in laparoscopic surgery for endometriosis. PMID:16385658

Time Dependent Heterogeneous Vehicle Routing Problem for Catering Service Delivery Problem

NASA Astrophysics Data System (ADS)

Azis, Zainal; Mawengkang, Herman

2017-09-01

The heterogeneous vehicle routing problem (HVRP) is a variant of vehicle routing problem (VRP) which describes various types of vehicles with different capacity to serve a set of customers with known geographical locations. This paper considers the optimal service deliveries of meals of a catering company located in Medan City, Indonesia. Due to the road condition as well as traffic, it is necessary for the company to use different type of vehicle to fulfill customers demand in time. The HVRP incorporates time dependency of travel times on the particular time of the day. The objective is to minimize the sum of the costs of travelling and elapsed time over the planning horizon. The problem can be modeled as a linear mixed integer program and we address a feasible neighbourhood search approach to solve the problem.

Tendencies in cerebral aneurism treatment: Analysis of a hospital series.

PubMed

Lago, A; López-Cuevas, R; Tembl, J I; Fortea, G; Górriz, D; Aparici, F; Parkhutik, V

To discover if there have been changes in the treatment time for SAH in our hospital environment. Comparative analysis of 571 patients treated at Hospital Universitari la Fe during 2 different time periods. The SAH-OLD group consisted of 462 patients attended consecutively between April 1997 and March 2005, while SAH-NEW comprised 109 patients attended consecutively between March 2007 and April 2010. We analysed demographic factors, risk factors, severity at time of admission, time to arteriography, diagnosis of aneurysm, use of surgical or endovascular treatment and time to treatment, frequency of neurological complications, in-hospital deaths, and modified Rankin Scale (mRS) at discharge. Mean time to arteriography was 2.18 ± 2.5 days for the SAH-OLD group and 2.37 ± 2.23 days, for the SAH-NEW group (P=.49). Mortality rates for SAH-OLD patients were calculated at 30%, compared to 18.3% in SAH-NEW patients (P=.01). Among patients surviving the hospital stay in the SAH-OLD group, 13.3% had an mRS > 3, compared to 21.3% of survivors in the SAH-NEW group (P=.06). Two hundred forty-five patients in the SAH-OLD group had cerebral aneurysms and 208 were treated (45% of the patient total). Sixty-five of the SAH-NEW patients received treatment (60% of the patient total, P=.007). In the SAH-OLD group, 62.9% of the patients underwent embolisation vs 74.6% in the SAH-NEW group (P=.08). Time to embolisation was 4.7 ± 8.2 days for SAH-OLD patients and 2.12 ± 2.2 days for SAH-NEW patients (P=.01). Twenty-two percent of SAH-OLD patients underwent surgery, compared to 25.4% in the SAH-NEW group (P=.62). Care for SAH patients has improved in this hospital: results include fewer mortalities, a higher number of treatments with a smaller proportion of endovascular treatments, and shorter times to treatment. Elapsed time to arteriography remains stable. Copyright © 2016 Sociedad Española de Neurología. Publicado por Elsevier España, S.L.U. All rights reserved.

Hippocampal “Time Cells”: Time versus Path Integration

PubMed Central

Kraus, Benjamin J.; Robinson, Robert J.; White, John A.; Eichenbaum, Howard; Hasselmo, Michael E.

2014-01-01

SUMMARY Recent studies have reported the existence of hippocampal “time cells,” neurons that fire at particular moments during periods when behavior and location are relatively constant. However, an alternative explanation of apparent time coding is that hippocampal neurons “path integrate” to encode the distance an animal has traveled. Here, we examined hippocampal neuronal firing patterns as rats ran in place on a treadmill, thus “clamping” behavior and location, while we varied the treadmill speed to distinguish time elapsed from distance traveled. Hippocampal neurons were strongly influenced by time and distance, and less so by minor variations in location. Furthermore, the activity of different neurons reflected integration over time and distance to varying extents, with most neurons strongly influenced by both factors and some significantly influenced by only time or distance. Thus, hippocampal neuronal networks captured both the organization of time and distance in a situation where these dimensions dominated an ongoing experience. PMID:23707613

Modeling And Simulation Of Multimedia Communication Networks

NASA Astrophysics Data System (ADS)

Vallee, Richard; Orozco-Barbosa, Luis; Georganas, Nicolas D.

1989-05-01

In this paper, we present a simulation study of a browsing system involving radiological image servers. The proposed IEEE 802.6 DQDB MAN standard is designated as the computer network to transfer radiological images from file servers to medical workstations, and to simultaneously support real time voice communications. Storage and transmission of original raster scanned images and images compressed according to pyramid data structures are considered. Different types of browsing as well as various image sizes and bit rates in the DQDB MAN are also compared. The elapsed time, measured from the time an image request is issued until the image is displayed on the monitor, is the parameter considered to evaluate the system performance. Simulation results show that image browsing can be supported by the DQDB MAN.

Event-based proactive interference in rhesus monkeys.

PubMed

Devkar, Deepna T; Wright, Anthony A

2016-10-01

Three rhesus monkeys (Macaca mulatta) were tested in a same/different memory task for proactive interference (PI) from prior trials. PI occurs when a previous sample stimulus appears as a test stimulus on a later trial, does not match the current sample stimulus, and the wrong response "same" is made. Trial-unique pictures (scenes, objects, animals, etc.) were used on most trials, except on trials where the test stimulus matched potentially interfering sample stimulus from a prior trial (1, 2, 4, 8, or 16 trials prior). Greater interference occurred when fewer trials separated interference and test. PI functions showed a continuum of interference. Delays between sample and test stimuli and intertrial intervals were manipulated to test how PI might vary as a function of elapsed time. Contrary to a similar study with pigeons, these time manipulations had no discernable effect on the monkey's PI, as shown by compete overlap of PI functions with no statistical differences or interactions. These results suggested that interference was strictly based upon the number of intervening events (trials with other pictures) without regard to elapsed time. The monkeys' apparent event-based interference was further supported by retesting with a novel set of 1,024 pictures. PI from novel pictures 1 or 2 trials prior was greater than from familiar pictures, a familiar set of 1,024 pictures. Moreover, when potentially interfering novel stimuli were 16 trials prior, performance accuracy was actually greater than accuracy on baseline trials (no interference), suggesting that remembering stimuli from 16 trials prior was a cue that this stimulus was not the sample stimulus on the current trial-a somewhat surprising conclusion particularly given monkeys.

Holocene behavior of the Brigham City segment: implications for forecasting the next large-magnitude earthquake on the Wasatch fault zone, Utah

USGS Publications Warehouse

Personius, Stephen F.; DuRoss, Christopher B.; Crone, Anthony J.

2012-01-01

The Brigham City segment (BCS), the northernmost Holocene‐active segment of the Wasatch fault zone (WFZ), is considered a likely location for the next big earthquake in northern Utah. We refine the timing of the last four surface‐rupturing (~Mw 7) earthquakes at several sites near Brigham City (BE1, 2430±250; BE2, 3490±180; BE3, 4510±530; and BE4, 5610±650 cal yr B.P.) and calculate mean recurrence intervals (1060–1500  yr) that are greatly exceeded by the elapsed time (~2500  yr) since the most recent surface‐rupturing earthquake (MRE). An additional rupture observed at the Pearsons Canyon site (PC1, 1240±50 cal yr B.P.) near the southern segment boundary is probably spillover rupture from a large earthquake on the adjacent Weber segment. Our seismic moment calculations show that the PC1 rupture reduced accumulated moment on the BCS about 22%, a value that may have been enough to postpone the next large earthquake. However, our calculations suggest that the segment currently has accumulated more than twice the moment accumulated in the three previous earthquake cycles, so we suspect that additional interactions with the adjacent Weber segment contributed to the long elapse time since the MRE on the BCS. Our moment calculations indicate that the next earthquake is not only overdue, but could be larger than the previous four earthquakes. Displacement data show higher rates of latest Quaternary slip (~1.3  mm/yr) along the southern two‐thirds of the segment. The northern third likely has experienced fewer or smaller ruptures, which suggests to us that most earthquakes initiate at the southern segment boundary.

Leaching of S-metolachlor, terbuthylazine, desethyl-terbuthylazine, mesotrione, flufenacet, isoxaflutole, and diketonitrile in field lysimeters as affected by the time elapsed between spraying and first leaching event.

PubMed

Milan, Marco; Ferrero, Aldo; Fogliatto, Silvia; Piano, Serenella; Vidotto, Francesco

2015-01-01

The effect of elapsed time between spraying and first leaching event on the leaching behavior of five herbicides (terbuthylazine, S-metolachlor, mesotrione, flufenacet, and isoxaflutole) and two metabolites (desethyl-terbuthylazine and diketonitrile) was evaluated in a 2011-2012 study in northwest Italy. A battery of 12 lysimeters (8.4 m(2) long with a depth of 1.8 m) were used in the study, each filled with silty-loam soil and treated during pre-emergence with the selected herbicides by applying a mixture of commercial products Lumax (4 L ha(-1)) and Merlin Gold (1 L ha(-1)). During treatment periods, no gravity water was present in lysimeters. Irrigation events capable of producing leaching (40 mm) were conducted on independent groups of three lysimeters on 1 day after treatment (1 DAT), 7 DAT, 14 DAT, and 28 DAT. The series was then repeated 14 days later. Leachate samples were collected a few days after irrigation; compounds were extracted by solid phase extraction and analyzed by high-performance liquid chromatography and gas chromatography-mass spectrometry. Under study conditions, terbuthylazine and S-metolachlor showed the highest leaching potentials. Specifically, S-metolachlor concentrations were always found above 0.25 µg L(-1). Desethyl-terbuthylazine was often detected in leached waters, in most cases at concentrations above 0.1 µg L(-1). Flufenacet leached only when irrigation occurred close to the time of herbicide spraying. Isoxaflutole and mesotrione were not measured (<0.1 µg L(-1)), while diketonitrile was detected in concentrations above 0.1 µg L(-1) on 1 DAT in 2011 only.

Simulation of Corrosion Process for Structure with the Cellular Automata Method

NASA Astrophysics Data System (ADS)

Chen, M. C.; Wen, Q. Q.

2017-06-01

In this paper, from the mesoscopic point of view, under the assumption of metal corrosion damage evolution being a diffusive process, the cellular automata (CA) method was proposed to simulate numerically the uniform corrosion damage evolution of outer steel tube of concrete filled steel tubular columns subjected to corrosive environment, and the effects of corrosive agent concentration, dissolution probability and elapsed etching time on the corrosion damage evolution were also investigated. It was shown that corrosion damage increases nonlinearly with increasing elapsed etching time, and the longer the etching time, the more serious the corrosion damage; different concentration of corrosive agents had different impacts on the corrosion damage degree of the outer steel tube, but the difference between the impacts was very small; the heavier the concentration, the more serious the influence. The greater the dissolution probability, the more serious the corrosion damage of the outer steel tube, but with the increase of dissolution probability, the difference between its impacts on the corrosion damage became smaller and smaller. To validate present method, corrosion damage measurements for concrete filled square steel tubular columns (CFSSTCs) sealed at both their ends and immersed fully in a simulating acid rain solution were conducted, and Faraday’s law was used to predict their theoretical values. Meanwhile, the proposed CA mode was applied for the simulation of corrosion damage evolution of the CFSSTCs. It was shown by the comparisons of results from the three methods aforementioned that they were in good agreement, implying that the proposed method used for the simulation of corrosion damage evolution of concrete filled steel tubular columns is feasible and effective. It will open a new approach to study and evaluate further the corrosion damage, loading capacity and lifetime prediction of concrete filled steel tubular structures.

Tuberculin reactivity in Bacillus Calmette-Guérin vaccinated subjects.

PubMed

Miret-Cuadras, P; Pina-Gutierrez, J M; Juncosa, S

1996-02-01

The Centre for Prevention and Control of Tuberculosis in Barcelona, Spain, where the staff appointed to Training Centers are examined. To check for tuberculin sensitivity due to Bacillus Calmette-Guérin (BCG) vaccine and ascertain its duration. We compared the results of a tuberculin test (TT) on vaccinated and non-vaccinated subjects. The induration diameter and the time elapsed between BCG vaccination and the TT were determined. Of the 2424 vaccinated subjects, 1489 (61.4%) reacted to TT (> or = 5 mm) and of the 3135 non-vaccinated, 905 (28.9%) reacted, a significant difference. Of 1978 subjects vaccinated between 6 and 14 years of age, 63.3% were TT reactors, compared to 23.9% of the 1948 non-vaccinated. Induration diameters > or = 15 mm amounted to 11% for vaccinated subjects and 8% for those not vaccinated, a significant difference. The time from vaccination to TT was 13-25 years. Of the 446 subjects vaccinated at birth, 237 were reactors (53.1%); of the 887 non-vaccinated subjects of the same age, 154 (17.4%) reacted. Reactors > or = 15 mm amounted to 40 (9%) for vaccinated subjects and 46 for non-vaccinated (5.2%), a significant difference. The time elapsed between vaccination and TT was 20-25 years. For 124 vaccinated subjects with a previous negative TT, a second test was positive for 87 (70.2%), and for 257 non-vaccinated it was positive for 64 (24.9%). The difference is due to a booster effect. BCG vaccination at birth and for school age children causes a reactivity to tuberculin which persists for 20 to 25 years. An induration diameter of > or = 15 mm does not exclude a vaccinal origin. For vaccinated subjects with a previous negative TT, it is necessary to exclude the booster effect.

Tape-Drop Transient Model for In-Situ Automated Tape Placement of Thermoplastic Composites

NASA Technical Reports Server (NTRS)

Costen, Robert C.; Marchello, Joseph M.

1998-01-01

Composite parts of nonuniform thickness can be fabricated by in-situ automated tape placement (ATP) if the tape can be started and stopped at interior points of the part instead of always at its edges. This technique is termed start/stop-on-the-part, or, alternatively, tape-add/tape-drop. The resulting thermal transients need to be managed in order to achieve net shape and maintain uniform interlaminar weld strength and crystallinity. Starting-on-the-part has been treated previously. This paper continues the study with a thermal analysis of stopping-on-the-part. The thermal source is switched off when the trailing end of the tape enters the nip region of the laydown/consolidation head. The thermal transient is determined by a Fourier-Laplace transform solution of the two-dimensional, time-dependent thermal transport equation. This solution requires that the Peclet number Pe (the dimensionless ratio of inertial to diffusive heat transport) be independent of time and much greater than 1. Plotted isotherms show that the trailing tape-end cools more rapidly than the downstream portions of tape. This cooling can weaken the bond near the tape end; however the length of the affected region is found to be less than 2 mm. To achieve net shape, the consolidation head must continue to move after cut-off until the temperature on the weld interface decreases to the glass transition temperature. The time and elapsed distance for this condition to occur are computed for the Langley ATP robot applying PEEK/carbon fiber composite tape and for two upgrades in robot performance. The elapsed distance after cut-off ranges from about 1 mm for the present robot to about 1 cm for the second upgrade.

Apparatus for measuring particle properties

DOEpatents

Rader, D.J.; Castaneda, J.N.; Grasser, T.W.; Brockmann, J.E.

1998-08-11

An apparatus is described for determining particle properties from detected light scattered by the particles. The apparatus uses a light beam with novel intensity characteristics to discriminate between particles that pass through the beam and those that pass through an edge of the beam. The apparatus can also discriminate between light scattered by one particle and light scattered by multiple particles. The particle`s size can be determined from the intensity of the light scattered. The particle`s velocity can be determined from the elapsed time between various intensities of the light scattered. 11 figs.

How do I manage an acute injury to the facial nerve?

PubMed

Colbert, Serryth; Coombes, Daryl; Godden, Daryl; Cascarini, Luke; Kerawala, Cyrus; Brennan, Peter A

2014-01-01

Paralysis of the facial nerve is a cause of considerable functional and aesthetic disfigurement. Damage to the upper trunk can result in eye complications with the risk of exposure keratitis. Numerous factors influence the therapeutic strategy: the cause of the injury, the time elapsed since injury, functional impairment, and the likelihood of recovery. We discuss the management of an acute injury to the facial nerve and focus on the surgical options. Copyright © 2013 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

Diagnosis and assessment of skeletal related disease using calcium 41

DOEpatents

Hillegonds, Darren J [Oakland, CA; Vogel, John S [San Jose, CA; Fitzgerald, Robert L [Encinitas, CA; Deftos, Leonard J [Del Mar, CA; Herold, David [Del Mar, CA; Burton, Douglas W [San Diego, CA

2012-05-15

A method of determining calcium metabolism in a patient comprises the steps of administering radioactive calcium isotope .sup.41Ca to the patient, allowing a period of time to elapse sufficient for dissemination and reaction of the radioactive calcium isotope .sup.41Ca by the patient, obtaining a sample of the radioactive calcium isotope .sup.41Ca from the patient, isolating the calcium content of the sample in a form suitable for precise measurement of isotopic calcium concentrations, and measuring the calcium content to determine parameters of calcium metabolism in the patient.

Diagnosis and assessment of skeletal related disease using calcium 41

DOEpatents

Hillegonds, Darren J.; Vogel, John S.; Fitzgerald, Robert L.; Deftos, Leonard J.; Herold, David; Burton, Douglas W.

2013-03-05

A method of determining calcium metabolism in a patient comprises the steps of administering radioactive calcium isotope .sup.41Ca to the patient, allowing a period of time to elapse sufficient for dissemination and reaction of the radioactive calcium isotope .sup.41Ca by the patient, obtaining a sample of the radioactive calcium isotope .sup.41Ca from the patient, isolating the calcium content of the sample in a form suitable for precise measurement of isotopic calcium concentrations, and measuring the calcium content to determine parameters of calcium metabolism in the patient.

The Neurological Complications of Nutritional Deficiency following Bariatric Surgery

PubMed Central

Becker, Danielle A.; Balcer, Laura J.; Galetta, Steven L.

2012-01-01

Neurologic complications of bariatric surgery have become increasingly recognized with the rising numbers of procedures and the increasing prevalence of obesity in the US. Deficits are most commonly seen with thiamine, vitamin B12, folate, vitamin D, vitamin E, and copper deficiencies. The neurological findings observed with these nutritional deficiencies are variable and include encephalopathy, optic neuropathy, myelopathy, polyradiculoneuropathy, and polyneuropathy. We review the neurological complications of bariatric surgery and emphasize that these findings may vary based on the specific type of bariatric surgery and time elapsed from the procedure. PMID:22970351

Co-Ordination Compounds as Sensitizers for Percussion Cap Compositions

DTIC Science & Technology

1949-01-01

table. TABLE III Time elapsed (hours) Mixture Sensitivity* (inches/ £ lb.) Ballistic Pendulum » Power coefficient C. of V. of trace lengths...dimension C = 50-52. The power co-efficient is obtained by dividing the average trace length for 10 of the caps under trial by the average trace ...resulting in a high C. of V. The trace lengths as measured were as follows: 8.25, 8.30, 4.55, 10.65, 9.55, 9.0C, 8.46, 8.42, 8.21, 8.34 inches. The

Apollo 16, LM-11 ascent propulsion system final flight evaluation

NASA Technical Reports Server (NTRS)

Griffin, W. G.

1974-01-01

The duty cycle for the LM-11 APS consisted of two firings, an ascent stage liftoff from the lunar surface, and the terminal phase initiation (TPI) burn. APS performance for the first firing was evaluated and found to be satisfactory. No propulsion data were received from the second APS burn; however, all indications were that the burn was nominal. Engine ignition for the APS lunar liftoff burn occured at the Apollo elapsed time (AET) of 175:31:47.9 (hours:minutes:seconds). Burn duration was 427.7 seconds.

APOLLO 17 - INFLIGHT

NASA Image and Video Library

1972-12-14

The Apollo 17 Lunar Module (LM) "Challenger" ascent stage leaves the Taurus-Littrow landing site as it makes its spectacular liftoff from the lunar surface, as seen in this reproduction taken from a color television transmission made by the color RCA TV camera mounted on the Lunar Roving Vehicle (LRV). The LRV-mounted TV camera, remotely controlled from the Mission Control Center (MCC) in Houston, made it possible for people on Earth to watch the fantastic event. The LM liftoff was at 188:01:36 ground elapsed time, 4:54:36 p.m. (CST), Thursday, December 14, 1972.

THE DISTRIBUTION OF 51CR-LABELED LYMPHOCYTES INTO ANTIGEN-STIMULATED MICE

PubMed Central

Zatz, Marion M.; Lance, Eugene M.

1971-01-01

The localization of syngeneic 51Cr-labeled lymph node cells was investigated in CBA/J mice previously challenged with sheep erythrocytes, Salmonella H antigen, keyhole limpet hemocyanin, C57BL/6J skin, or rat skin. The effect of time, dose, and route of antigen administration on lymphocyte migration was studied in both primary and secondary responses. When the distribution pattern of lymphocytes was examined after 20–24 hr, it was found that increased localization of labeled cells occurred in spleen after intravenous or intraperitoneal antigen injection, and in draining lymph nodes after subcutaneous antigen injection or skin grafting. Increased localization (trapping) of lymphocytes was antigen dose dependent and could be demonstrated when 1–6 hr had elapsed between intravenous antigen administration, or when 24 hr had elapsed between subcutaneous antigen administration and intravenous cell infusion. Trapping was transient, lasting approximately 24 hr. Maximal trapping of lymphocytes in the draining nodes occurred 9 days after skin grafting in the first-set allograft response, and 3 days after grafting in the second-set allograft and first-set xenograft responses. The cell type trapped, the specificity and mechanism of action of the trap, and the role of lymphocyte trapping in the initiation of immune responses are discussed. PMID:4934148

The SLE-key test serological signature: new insights into the course of lupus.

PubMed

Putterman, Chaim; Pisetsky, David S; Petri, Michelle; Caricchio, Roberto; Wu, Alan H B; Sanz, Ignacio; Oates, Jim C; Wallace, Steve; Sorek, Rachel; Gerwien, Robert; Safer, Pennina; Jakobi-Brook, Keren; Cohen, Irun R

2018-06-04

We previously described the multiplex autoantibody SLE-key Rule-Out test, which detects a signature of autoantibody reactivity that distinguishes healthy subjects from SLE patients with 94% sensitivity, 75% specificity and 93% negative predictive value; thus, an individual manifesting a positive Rule-Out test score is unlikely to have SLE (e.g. lupus is excluded). The objective of this current study was to evaluate the stability of the lupus-associated signature over time. We used banked serum samples from healthy subjects (n = 51) and lupus patients (n = 50 individual samples and n = 181 paired samples, for a total of n = 412 serum samples). The samples were drawn at different times after diagnosis to analyse the impact on the SLE-key Rule-Out test of time elapsed since diagnosis and any changes in disease activity (as reflected by the SLEDAI score). The SLE signature remains stable for the first 10 years after diagnosis; in this time frame, <10% of patients manifested a positive Rule-Out score and the SLE-key Rule-Out score was independent of the underlying disease activity as reflected by the SLEDAI score. After ⩾10 years, ∼30% of lupus subjects scored as SLE Ruled-Out; the proportion of patients manifesting this status was even greater in the subset of individuals with a SLEDAI score of 0. These findings raise the possibility that a significant number of SLE patients manifest a change in their serological signature over time, and that such a signature change may signify an evolution in the immunological features of their disease relevant to patient management.

Extreme reaction times determine fluctuation scaling in human color vision

NASA Astrophysics Data System (ADS)

Medina, José M.; Díaz, José A.

2016-11-01

In modern mental chronometry, human reaction time defines the time elapsed from stimulus presentation until a response occurs and represents a reference paradigm for investigating stochastic latency mechanisms in color vision. Here we examine the statistical properties of extreme reaction times and whether they support fluctuation scaling in the skewness-kurtosis plane. Reaction times were measured for visual stimuli across the cardinal directions of the color space. For all subjects, the results show that very large reaction times deviate from the right tail of reaction time distributions suggesting the existence of dragon-kings events. The results also indicate that extreme reaction times are correlated and shape fluctuation scaling over a wide range of stimulus conditions. The scaling exponent was higher for achromatic than isoluminant stimuli, suggesting distinct generative mechanisms. Our findings open a new perspective for studying failure modes in sensory-motor communications and in complex networks.

Cardowan coal mine explosion: experience of a mass burns incident.

PubMed Central

Allister, C; Hamilton, G M

1983-01-01

A coal mine explosion 1700 feet (516 m) underground and two miles (3.2 km) from the pit head resulted in 40 casualties. Two hours elapsed between the explosion and the arrival of patients at hospital. Six patients suffered mechanical injuries, only one of which was life threatening. Thirty six suffered burns; in 18 over 15% of the total body surface area was affected. Nineteen patients had a mild respiratory upset requiring oxygen treatment. The average length of inpatient stay in those admitted was 24 days. Early assessment and treatment in the accident and emergency department was relatively simple because of the large proportion of burn injuries. Lack of communication between site and hospital made administration of the disaster difficult. PMID:6409324

Sorptivity of rocks and soils of the van Genuchten-Mualem type

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zimmerman, R.W.; Bodvarsson, G.S.

1991-06-01

One hydrological process that will have great relevance to the performance of the proposed underground radioactive waste repository at Yucca Mountain, Nevada, is that of the absorption of water from a water-filled fracture into the adjacent unsaturated rock formation. The rate at which water is imbibed by a rock depends on the hydrological properties of the rock and on the initial saturation (or initial capillary suction) of the formation. The hydrological properties that affect imbibition are the relative permeability function and the capillary pressure function. These functions are often collectively referred to as the `characteristic functions` of the porous medium.more » For one-dimensional absorption, it can be shown that, regardless of the details of the characteristic functions, the total amount of water imbibed by the formation, per unit surface area, will be proportional to the square root of the elapsed time. Hence the ability of a rock or soil to imbibe water can be quantified by a parameter known as the sorptivity S, which is defined such that the cumulative volumetric liquid influx per unit area is given by Q = S{radical}t. The paper discusses the simplification of these characteristic functions of porous medium.« less

Gusev Dust Devil, sol 532

NASA Technical Reports Server (NTRS)

2005-01-01

This movie clip shows a dust devil seen by NASA's Mars Exploration Rover Spirit during the rover's 532nd martian day, or sol (July 2, 2005). The dust-carrying whirlwind is moving across a plain inside Gusev Crater and viewed from Spirit's vantage point on hills rising from the plain. The clip consists of frames taken by Spirit's navigation camera, processed to enhance contrast for anything in the images that changes from frame to frame. The total elapsed time during the taking of these frames was 8 minutes, 48 seconds.

Spirit began seeing dust devil activity around the beginning of Mars' spring season. Activity increased as spring continued, but fell off again for about two weeks during a dust storm. As the dust storm faded away, dust devil activity came back. In the mid-afternoons as the summer solstice approached, dust devils were a very common occurrence on the floor of Gusev crater. The early-spring dust devils tended to move southwest-to-northeast, across the dust devil streaks in Gusev seen from orbit. Increasingly as the season progresses, the dust devils are seen moving northwest-to-southeast, in the same direction as the streaks. Scientists are watching for the big dust devils that leave those streaks.

Related factors with extravasation of non-cytostatic agents in peripheral vein catheters.

PubMed

Fernández-García, Cristina; Mata-Peón, Esther; Avanzas-Fernández, Sara

To know the independent variables related to the occurrence of extravasation in patients with peripheral vein catheters (PVC). Retrospective study carried out in 6 longitudinal cuts between July 2013 an January 2014. A total of 1,442 PVC were reviewed, of which 730 met the inclusion criteria, and were divided into 2 groups: extravasation and not extravasation, with 365 cases each. The variables of age, gender, admission unit, catheter gauge, insertion site, previous insertion into the same limb, hospital unit where the insertion took place, communication difficulties, personal health history and analyzed parenterally drug administered were considered. Risk factors to develop extravasation were: female gender, with previous insertion in the same limb, <72h PVC of insertion, communication difficulties, personal health history of neoplasia and KCl, gentamicin or beta lactam treatment. Our study allows to know the variables that are related to the emergence of extravasations in patients with non-cancer treatments (gender, medical service of admission, catheter gauge, elapsed time since the insertion, patient communication difficulties, personal health history, and intravenous treatments), as well as the factors that may be considered protective. Copyright © 2016 Elsevier España, S.L.U. All rights reserved.

Barriers to Diagnosis Access for Chagas Disease in Colombia

PubMed Central

Toquica Gahona, Christian Camilo; Rodríguez Hernández, Jorge Martín

2018-01-01

Chagas disease is the leading cause of nonischemic cardiomyopathy in Latin America. Timely access to diagnosis and trypanocidal treatment and preventive tools for millions of infected people continues to be a challenge. The purpose of this study was to identify potential barriers for the diagnosis of Chagas disease in Colombia from the perspective of healthcare providers. Using a simultaneous mixed-methods study design, we analyzed trends in access to screening and diagnosis for Chagas disease in Colombia and assessed the national barriers to access. The main barriers to access at the national level included a limited governmental public health infrastructure for the diagnosis of Chagas disease and limited physician awareness and knowledge of the disease. Data indicate that 1.5% of total expected cases based on national prevalence estimates were reported. Few public health laboratories have the capacity to perform complementary tests for the diagnosis of Chagas disease and almost 6 months elapse between the requests of the tests and the confirmation of the disease. This study shows that infected people must overcome a number of barriers to achieve diagnosis. Reducing barriers to early diagnosis of Chagas disease is an important goal in the fight against the disease. PMID:29568648

Mission description. [major mission events and data collection periods during Apollo 17 lunar exploration

NASA Technical Reports Server (NTRS)

Baldwin, R. R.

1973-01-01

The accomplishments of the Apollo 17 flight are discussed. The scientific objectives included geological surveying and sampling of materials and surface features in a preselected area of the Taurus-Littrow region, deploying and activating surface experiments, and conducting inflight experiments and photographic tasks during lunar orbit and transearth coast. The individual Apollo 17 experiments and photographic tasks are presented in outline form. Charts are developed to show the major mission events and data collection periods correlated to Greenwich Mean Time and ground elapsed time. Maps of the lunar surface ground track envelope for the Apollo 17 orbiting spacecraft for revolutions one to seventy-five is shown.

On the pilot's behavior of detecting a system parameter change

NASA Technical Reports Server (NTRS)

Morizumi, N.; Kimura, H.

1986-01-01

The reaction of a human pilot, engaged in compensatory control, to a sudden change in the controlled element's characteristics is described. Taking the case where the change manifests itself as a variance change of the monitored signal, it is shown that the detection time, defined to be the time elapsed until the pilot detects the change, is related to the monitored signal and its derivative. Then, the detection behavior is modeled by an optimal controller, an optimal estimator, and a variance-ratio test mechanism that is performed for the monitored signal and its derivative. Results of a digital simulation show that the pilot's detection behavior can be well represented by the model proposed here.

KSC-06pd1592

NASA Image and Video Library

2006-07-17

KENNEDY SPACE CENTER, FLA. - A crew transport vehicle (CTV), a modified “people mover” used at airports, approaches the orbiter Discovery after the vehicle was "safed" for crew departure. The crew exits the orbiter into a crew hatch access vehicle and, after a brief medical examination, transfers into the CTV. Discovery's smooth and perfect landing after completing mission STS-121 was on time at 9:14 a.m. EDT on Runway 15 of NASA's Shuttle Landing Facility after traveling 5.3 million miles on 202 orbits. Mission elapsed time was 12 days, 18 hours, 37 minutes and 54 seconds. The landing is the 62nd at Kennedy Space Center and the 32nd for Discovery. Photo credit: NASA/Kim Shiflett

Do the Reasons for Ceramic-on-ceramic Revisions Differ From Other Bearings in Total Hip Arthroplasty?

PubMed

Migaud, Henri; Putman, Sophie; Kern, Grégory; Isida, Ronald; Girard, Julien; Ramdane, Nassima; Delaunay, Christian P; Hamadouche, Moussa

2016-10-01

Despite widespread use of ceramic-on-ceramic (CoC) in total hip arthroplasty (THA) during the past 10 years, little is known about why revisions are performed in hips with this bearing or the time elapsed before revision. The purposes of this study were: (1) Do the reasons for first revision differ between CoC bearings and other bearing couples? (2) Does the time to revision differ between CoC and other bearing couples? (3) Are there unique reasons for revisions of CoC bearings? All members of the Société Française de Chirurgie Orthopédique et Traumatologique (SoFCOT) who performed ≥ 30 revisions per year were invited to participate in this multicenter, prospective, observational study. Our data represent 12% of the revision procedures performed in France. A total of 2107 first revisions of THA (from January 2010 to December 2011) were done in 2107 patients (1201 females [57%] and 906 males [43%]; median age, 73 years; age range, 17-104 years) at the time of surgery after a median of 11 years (range, 0 day-42 years) after the primary THA. There were 238 of 2107 (11%) CoC, 148 of 2107 (7%) metal-on-metal (MoM), and 1721 of 2017 (82%) metal-on-polyethylene (MoP) bearings. The reasons for reoperation differed according to the bearing component: (1) for the MoP reference bearing (odds ratio [OR]; 95% confidence interval), cup loosening occurred in 698 of 1721 hips (41%), periprosthetic fracture in 220 of 1721 hips (13%), and osteolysis in 213 of 1721 hips (12%); (2) for CoC, cup loosening occurred in 41 of 238 hips (17%) (OR, 0.31 [0.22-0.43; p < 0.001), infection in 39 of 238 hips (16%) (OR, 1.63 [1.12-2.37]; p = 0.01), and dislocation in 23 of 238 hips (10%) (OR, 0.9 [0.57-1.42]; p = 0.9); (3) for MoM, cup loosening occurred in 28 of 148 hips (19%) (OR, 0.34 [0.22-0.52]; p < 0.001), adverse reaction to metallic debris in 26 of 148 hips (18%) (OR, 18.12 [9.84-33.4]; p < 0.001), and infection in 16 of 148 hips (11%) (OR, 1 [0.59-1.73]; p = 0.9). In comparison with MoP, osteolysis was rarely the reason for revision in CoC (four of 238 hips [2%]; OR, 0.12 [0.05-0.33]; p < 0.001), but this bearing was frequently revised because of iliopsoas irritation (18 of 238 hips [8%]; OR, 4.9 [2.7-9]; p < 0.001). The time elapsed before revision differed between bearings: median of 3 years (range, 3 days to 28 years) for CoC and 4 years (range, 14 days to 37 years) for MoM versus a median 13 years (range, 0 day to 42 years) for MoP (p < 0.001). Thirty-seven of the 238 revisions (16%) were directly related to ceramic use (ceramic breakage [n = 23], squeaking [n = 6], impingement [n = 7], incorrect ceramic insert insertion [n = 1]). No factors were identified that contributed to breakage of the 12 bulk ceramic components (eight heads, four inserts, four of 12 Delta ceramic). No factors were associated with squeaking, iliopsoas irritation, or impingement, but component orientation was not assessed. The reasons and time to first revision differed between CoC and other bearings. CoC THAs are revised earlier and are sensitive to mechanical problems such as impingement, squeaking, and ceramic rupture that did not disappear with introduction of Delta ceramics and large-diameter (≥ 36 mm) bearings. CoC was rarely revised for osteolysis, but a high rate of iliopsoas irritation requires further investigation. Level III, therapeutic study.

Using Retrieval Cues to Attenuate Return of Fear in Individuals With Public Speaking Anxiety.

PubMed

Shin, Ki Eun; Newman, Michelle G

2018-03-01

Even after successful exposure, relapse is not uncommon. Based on the retrieval model of fear extinction (e.g., Vervliet, Craske, & Hermans, 2013), return of fear can occur after exposure due to an elapse of time (spontaneous recovery) or change in context (contextual renewal). The use of external salient stimuli presented throughout extinction (i.e., retrieval cues [RCs]) has been suggested as a potential solution to this problem (Bouton, 2002). The current study examined whether RCs attenuated return of fear in individuals with public speaking anxiety. Sixty-five participants completed a brief exposure while presented with two RC stimuli aimed at a variety of senses (visual, tactile, olfactory, and auditory). Later, half the participants were tested for return of fear in a context different from the exposure context, and the other half in the same context. Half of each context group were presented with the same cues as in exposure, while the other half were not. Return of fear due to an elapse of time, change in context, and effects of RCs were evaluated on subjective, behavioral, and physiological measures of anxiety. Although contextual renewal was not observed, results supported effects of RCs in reducing spontaneous recovery on behavioral and physiological measures of anxiety. There was also evidence that participants who were reminded of feeling anxious during exposure by the RCs benefited more from using them at follow-up, whereas those who perceived the cues as comforting (safety signals) benefited less. Clinical implications of the findings are discussed. Copyright © 2017. Published by Elsevier Ltd.

Usefulness of skin immunofluorescence for distinguishing SLE from SLE-like renal lesions: a pilot study.

PubMed

L'Erario, Ines; Frezzolini, Alessandra; Ruggiero, Barbara; De Pità, Ornella; Emma, Francesco; Gianviti, Alessandra

2011-01-01

Lupus nephritis (LN) may represent a diagnostic problem, particularly in pediatric patients that present with typical histological lesions but do not fulfill the American Rheumatism Association (ARA) criteria for the diagnosis of systemic lupus erythematosus (SLE). Based on the well-described deposition of immunoglobulins (Ig) and complement at the dermoepithelial junction in SLE, we hypothesized that skin biopsies may help in the diagnosis of LN. To test this hypothesis, we carried out a pilot study, performing a skin biopsy in 22 patients with LN and 13 patients with lupus-like lesions, regardless of the time elapsed from onset of renal disease. The latter group of patients was further divided into a purely renal group, designated as isolated full-house nephropathy (FHN), and a dubious cases group, presenting with additional clinical and biological features consistent with SLE but insufficient for diagnosing SLE. None of the 6 isolated FHN patients had positive skin immunofluorescence. Conversely, 5/7 patients in the dubious cases group (p<0.02) and 13/22 in the LN group (p<0.002) had positive staining for C1q, and 5/7 patients in the dubious cases group (p<0.02) and 16/22 patients in the LN group (p<0.001) had positive staining for IgM. No correlation was observed with the time elapsed from the initial diagnosis. These data suggest that skin biopsies may help distinguishing LN from isolated FHN. In addition, they identify an intermediate group of patients with evidence of systemic involvement despite the absence of a sufficient number of ARA criteria to be labeled as SLE.

Accuracy of paramedic identification of stroke and transient ischemic attack in the field.

PubMed

Smith, W S; Isaacs, M; Corry, M D

1998-01-01

To determine the accuracy of acute stroke identification by paramedics in an urban emergency medical services system. Retrospective chart review of all patient encounters by paramedics resulting in transport to two university hospitals during a six-month period. Subjects were identified by paramedic coding of stroke/transient ischemic attach (TIA) or final hospital discharge ICD-9 diagnosis of acute stroke and TIA. The sensitivity and positive predictive value for paramedic identification of stroke were calculated, and the time intervals from symptom onset to various points along the patients' prehospital and hospital courses were identified. Ninety-six patients were identified, of whom 81 met the diagnosis of acute stroke or TIA. Paramedics identified 49 of these 81 patients (sensitivity 61%). Fifteen patients were identified by paramedics as having a stroke when the patient ultimately had a different diagnosis (positive predictive value 77%) Patients or their families waited on average 2.5 +/- 3.6 (SD) hours before accessing 911, and a mean of 5.1 +/- 4.0 (SD) hours elapsed from symptom onset until head imaging studies were obtained. Paramedics in San Francisco County were correct three-fourths of the time when their documentation listed patients as having stroke/TIA. However, they did not identify 39% of stroke victims, a patient population who may benefit from urgent therapy. A substantial period elapses before stroke victims access 911. This highlights the need to develop an educational program for the community at risk for stroke, and another for paramedics directed toward more accurate identification of acute stroke victims.

Conservative endovascular management of retained placenta accreta with marked vascularity after abortion or delivery.

PubMed

Takeda, Akihiro; Koike, Wataru

2017-12-01

To report our experience on the value of transcatheter arterial embolization (TAE) or transcatheter arterial chemoembolization (TACE) for the uterus-preserving management of retained placenta accreta with marked vascularity after abortion or delivery. Thirty-eight consecutive women with retained placenta accreta were retrospectively analyzed over a 5-year period. When elevated levels of serum β-hCG (> 25 mIU/mL) were detected, TACE with dactinomycin was chosen for devascularization along with cytotoxic effects on active trophoblasts; in contrast, if the serum β-hCG level was low (≤ 25 mIU/mL), TAE was chosen. After confirming devascularization, the additional need for hysteroscopic resection and systemic methotrexate administration was individually determined. The most frequent sign and symptom in the abortion group was significant hemorrhaging, while a hypervascular mass detected at a regular check-up was the most frequent in the delivery group. The median time elapsed between abortion and endovascular management was 36 days, and the median time elapsed after delivery was 31.5 days. TACE was performed more frequently than TAE in the abortion group, while TAE was the more frequent procedure in the delivery group. In 10 and 11 cases, after abortion and delivery, respectively, hysteroscopic resection was performed. Systemic methotrexate administration was additionally done in three and one cases after abortion and delivery, respectively. Uterine preservation was achieved in all cases. This case series emphasizes that endovascular embolization is an effective key intervention with or without additional therapies for uterus-preserving management of retained placenta accreta with marked vascularity after abortion or delivery.

The effects of warmed intravenous fluids, combined warming (warmed intravenous fluids with humid-warm oxygen), and pethidine on the severity of shivering in general anesthesia patients in the recovery room

PubMed Central

Nasiri, Ahmad; Akbari, Ayob; Sharifzade, GholamReza; Derakhshan, Pooya

2015-01-01

Background: Shivering is a common complication of general and epidural anesthesia. Warming methods and many drugs are used for control of shivering in the recovery room. The present study is a randomized clinical trial aimed to investigate the effects of two interventions in comparison with pethidine which is the routine treatment on shivering in patients undergoing abdominal surgery with general anesthesia. Materials and Methods: Eighty-seven patients undergoing abdominal surgery by general anesthesia were randomly assigned to three groups (two intervention groups in comparison with pethidine as routine). Patients in warmed intravenous fluids group received pre-warmed Ringer serum (38°C), patients in combined warming group received pre-warmed Ringer serum (38°C) accompanied by humid-warm oxygen, and patients in pethidine group received intravenous pethidine routinely. The elapsed time of shivering and some hemodynamic parameters of the participants were assessed for 20 min postoperatively in the recovery room. Then the collected data were analyzed by software SPSS (v. 16) with the significance level being P < 0.05. Results: The mean of elapsed time in the warmed intravenous serum group, the combined warming group, and the pethidine group were 7 (1.5) min, 6 (1.5) min, and 2.8 (0.7) min, respectively, which was statistically significant (P < 0.05). The body temperatures in both combined warming and pethidine groups were increased significantly (P < 0.05). Conclusions: Combined warming can be effective in controlling postoperative shivering and body temperature increase. PMID:26793258

Clinically inactive disease in a cohort of children with new-onset polyarticular juvenile idiopathic arthritis treated with early aggressive therapy: time to achievement, total duration, and predictors.

PubMed

Wallace, Carol A; Giannini, Edward H; Spalding, Steven J; Hashkes, Philip J; O'Neil, Kathleen M; Zeft, Andrew S; Szer, Ilona S; Ringold, Sarah; Brunner, Hermine I; Schanberg, Laura E; Sundel, Robert P; Milojevic, Diana S; Punaro, Marilynn G; Chira, Peter; Gottlieb, Beth S; Higgins, Gloria C; Ilowite, Norman T; Kimura, Yukiko; Johnson, Anne; Huang, Bin; Lovell, Daniel J

2014-06-01

To determine the elapsed time while receiving aggressive therapy to the first observation of clinically inactive disease (CID), total duration of CID and potential predictors of this response in a cohort of children with recent onset of polyarticular juvenile idiopathic arthritis (poly-JIA). Eighty-five children were randomized blindly to methotrexate (MTX), etanercept, and rapidly tapered prednisolone (MEP) or MTX monotherapy and assessed for CID over 1 year of treatment. Patients who failed to achieve intermediary endpoints were switched to open-label MEP treatment. Fifty-eight (68.2%) of the 85 patients achieved CID at 1 or more visits including 18 who received blinded MEP, 11 while receiving MTX monotherapy, and 29 while receiving open-label MEP. Patients starting on MEP achieved CID earlier and had more study days in CID compared to those starting MTX, but the differences were not significantly different. Patients given MEP (more aggressive therapy) earlier in the disease course were statistically more likely to have a higher proportion of followup visits in CID than those with longer disease course at baseline. Those who achieved American College of Rheumatology Pediatric 70 response at 4 months had a significantly greater proportion of followup visits in CID, compared to those who failed to achieve this improvement (p < 0.0001). Of the 32 patients who met criteria for CID and then lost CID status, only 3 fulfilled the definition of disease flare. Shorter disease duration prior to treatment, a robust response at 4 months, and more aggressive therapy result in a higher likelihood and longer duration of CID in patients with poly-JIA. The original trial from which data for this analysis were obtained is registered on www.clinicaltrials.gov NCT 00443430.

Development of a prototype chest digital tomosynthesis R/F system

NASA Astrophysics Data System (ADS)

Choi, Sunghoon; Lee, Haenghwa; Lee, Donghoon; Choi, Seungyeon; Shin, Jungwook; Jang, Woojin; Seo, Chang-Woo; Kim, Hee-Joung

2017-03-01

Digital tomosynthesis has an advantage of low radiation dose compared to conventional computed tomography (CT) by utilizing small number of projections ( 80) acquired over a limited angular range. It can produce 3D volumetric data although they may have some artifacts due to incomplete sampling. Based upon these attractive merits, we developed a prototype digital tomosynthesis R/F system especially for the purpose of applications in chest imaging. Prototype chest digital tomosynthesis (CDT) R/F system contains an X-ray tube with high power R/F pulse generator, flat-panel detector, R/F table, electromechanical radiographic subsystems including precise motor controller, and a reconstruction server. For image reconstruction, users could select the reconstruction option between analytic and iterative methods. Reconstructed images of Catphan700 and LUNGMAN phantoms clearly and rapidly described the internal structures of the phantoms using graphics processing unit (GPU) programming. Contrast-to-noise ratio (CNR) values of the CTP682 module was higher in images using the simultaneous algebraic reconstruction technique (SART) than those using filtered backprojection (FBP) for all materials by factors of 2.60, 3.78, 5.50, 2.30, 3.70, and 2.52 for air, lung foam, low density polyethylene (LDPE), Delrin (acetal homopolymer resin), bone 50% (hydroxyapatite), and Teflon, respectively. Total elapsed times for producing 3D volume were 2.92 sec and 86.29 sec on average for FBP and SART (20 iterations), respectively. The times required for reconstruction were clinically feasible. Moreover, the total radiation dose from the system (5.68 mGy) could demonstrate a significant lowered radiation dose compared to conventional chest CT scan. Consequently, our prototype tomosynthesis R/F system represents an important advance in digital tomosynthesis applications.

Development of a prototype chest digital tomosynthesis (CDT) R/F system with fast image reconstruction using graphics processing unit (GPU) programming

NASA Astrophysics Data System (ADS)

Choi, Sunghoon; Lee, Seungwan; Lee, Haenghwa; Lee, Donghoon; Choi, Seungyeon; Shin, Jungwook; Seo, Chang-Woo; Kim, Hee-Joung

2017-03-01

Digital tomosynthesis offers the advantage of low radiation doses compared to conventional computed tomography (CT) by utilizing small numbers of projections ( 80) acquired over a limited angular range. It produces 3D volumetric data, although there are artifacts due to incomplete sampling. Based upon these characteristics, we developed a prototype digital tomosynthesis R/F system for applications in chest imaging. Our prototype chest digital tomosynthesis (CDT) R/F system contains an X-ray tube with high power R/F pulse generator, flat-panel detector, R/F table, electromechanical radiographic subsystems including a precise motor controller, and a reconstruction server. For image reconstruction, users select between analytic and iterative reconstruction methods. Our reconstructed images of Catphan700 and LUNGMAN phantoms clearly and rapidly described the internal structures of phantoms using graphics processing unit (GPU) programming. Contrast-to-noise ratio (CNR) values of the CTP682 module of Catphan700 were higher in images using a simultaneous algebraic reconstruction technique (SART) than in those using filtered back-projection (FBP) for all materials by factors of 2.60, 3.78, 5.50, 2.30, 3.70, and 2.52 for air, lung foam, low density polyethylene (LDPE), Delrin® (acetal homopolymer resin), bone 50% (hydroxyapatite), and Teflon, respectively. Total elapsed times for producing 3D volume were 2.92 s and 86.29 s on average for FBP and SART (20 iterations), respectively. The times required for reconstruction were clinically feasible. Moreover, the total radiation dose from our system (5.68 mGy) was lower than that of conventional chest CT scan. Consequently, our prototype tomosynthesis R/F system represents an important advance in digital tomosynthesis applications.

Inappropriate breast secretions of possible bacterial etiology in the parous nonpuerperal female.

PubMed

Freeman, J J; Altieri, R H; Freeman, A H; Kuo, T; Sardinha, F; Buckingham, C C; Sklar, J J; Dyroff, K; Floyd, A

1994-03-01

This article presents two cases of spontaneous green breast secretions of parous nonpuerperal patients. To understand the nature of these secretions, bacterial evaluations and subsequent treatment were undertaken. Case 1 culture and sensitivity studies from breast secretions were commenced within 24 hours yielding an isolate identified as Staphylococcus epidermidis, with sensitivity to cephalothin, erythromycin, and tetracycline but resistant to penicillin. Cephalothin, 500 mg four times a day for 10 days, followed by erythromycin 100 mg twice a day for 10 days and doxycycline 100 mg twice a day for 10 days, did not alter the breast secretions. Four weeks later, ciprofloxacin HCI 500 mg twice a day for 6 weeks caused a 50% decrement in breast secretion at 4 weeks but increased clinical depression. At 6 weeks, no evidence of breast secretions persisted. Mental depression decreased within 2 weeks postciprofloxacin treatment. In Case 2, a total of 35 minutes elapsed between sample collection and initiation of culture and sensitivity studies. Moraxella osloensis was identified and found sensitive to ampicillin and tetracycline but resistant to trimethoprim. Ampicillin 500 mg four times a day for 10 days and doxycycline 100 mg twice a day by mouth for 10 days were administered at 2-week intervals with no effect on breast discharge. After 4 weeks of treatment failure, ciprofloxacin HCI 500 mg twice a day for 6 weeks caused a 50% decrease in discharge at 2 weeks and total elimination at 6 weeks. Lethargy during treatment ceased with termination of therapy. These results support the importance of bacterial evaluation of breast secretions with subsequent antibiotic therapy.(ABSTRACT TRUNCATED AT 250 WORDS)

The Dynamical Evolution of the Earth-Moon Progenitors. 1; Motivation and Methodology

NASA Technical Reports Server (NTRS)

Lissuer, Jack; Rivera, E.; Duncan, M. J.; Levison, H. F.; DeVincenzi, Donald (Technical Monitor)

1999-01-01

The Giant Impact Hypothesis was introduced in the mid-1970's after consideration of results from the Apollo Moon missions. This hypothesis best explains the similarity in elemental proportions in lunar and terrestrial rocks, the depletion of lunar volatiles, the lack of lunar iron. and the large angular momentum in the Earth-Moon system. Comparison between the radiometric ages of inclusions in the most primitive meteorites and those of inclusions in the oldest lunar rocks and the differentiation age of Earth suggests that the Earth-Moon system formed about 100 Myr after the oldest meteorites. In addition, the age of the famous Martian meteorite ALH84001 and an early solidification time estimated from the Martian crust, suggest that the inner Solar System was fairly clear of large bodies about 10 Myr after the oldest meteorites formed. Thus, the 'standard model' suggests that for a period of several tens of millions of years the terrestrial planet region had few. if any, lunar-sized bodies and there were five terrestrial planets, Mercury, Venus, the two progenitors of the Earth-Moon system, and Mars. To simulate the dynamics of the Solar System before the hypothesized Moon-forming impact, we are integrating the Solar System with the Earth-Moon system replaced by two bodies in heliocentric orbits between Venus and Mars. The total (orbital) angular momentum of the Earth-Moon progenitors is that of the present Earth-Moon system, and their total mass is that of the Earth-Moon system. We are looking at ranges in mass ratio and initial values for eccentricity, inclination. and semi-major axis. We are using the SYMBA integrator to integrate these systems until a collision occurs or a time of 200 Myr elapses. Results are presented in a companion paper.

The Dynamical Evolution of the Earth-Moon Progenitors. 1; Motivation and Methodology

NASA Technical Reports Server (NTRS)

Lissauer, J. J.; Rivera, E.; Duncan, M. J.; Levison, H. F.

1998-01-01

The giant impact hypothesis was introduced in the mid-1970s after consideration of results from the Apollo missions. This hypothesis best explains the similarity in elemental proportions in lunar and terrestrial rocks, the depletion of lunar volatiles, the lack of lunar Fe, and the large angular momentum in the Earth-Moon system. Comparison between the radiometric ages of inclusions in the most primitive meteorites and in the oldest lunar rocks and the differentiation age of Earth suggests that the Earth-Moon system formed about100 m.y. after the oldest meteorites. In addition, the age of the famous martian meteorite ALH 84001 and an early Martian solidification time obtained by Lee and Halliday suggest that the inner solar system was fairly clear of large bodies about 10 m.y. after the oldest meteorites formed. Thus, the "standard model" suggests that for several tens of millions of years, the terrestrial planet region had few, if any, lunar-sized bodies, and there were five terrestrial planets: Mercury, Venus, the two progenitors of the Earth-Moon system, and Mars. To simulate the dynamics of the solar system before the hypothesized Moon-forming impact, we are integrating the solar system with the Earth-Moon system replaced by two bodies in heliocentric orbits between Venus and Mars. The total (orbital) angular momentum of the Earth-Moon progenitors is that of the present Earth-Moon system, and their total mass is that of the Earth-Moon System. We are looking at ranges in mass ratio and initial values for eccentricity, inclination, and semimajor axis. We are using the SYMBA integrator to integrate these systems until a collision occurs or a time of 200 m.y. elapses. Results are presented in a companion abstract, (also presented at this meeting).

Phosphorus and nitrate nitrogen in runoff following fertilizer application to turfgrass.

PubMed

Shuman, L M

2002-01-01

Intensively managed golf courses are perceived by the public as possibly adding nutrients to surface waters via surface transport. An experiment was designed to determine the transport of nitrate N and phosphate P from simulated golf course fairways of 'Tifway' bermudagrass [Cynodon dactylon (L.) Pers.]. Fertilizer treatments were 10-10-10 granular at three rates and rainfall events were simulated at four intervals after treatment (hours after treatment, HAT). Runoff volume was directly related to simulated rainfall amounts and soil moisture at the time of the event and varied from 24.3 to 43.5% of that added for the 50-mm events and 3.1 to 27.4% for the 25-mm events. The highest concentration and mass of phosphorus in runoff was during the first simulated rainfall event at 4 HAT with a dramatic decrease at 24 HAT and subsequent events. Nitrate N concentrations were low in the runoff water (approximately 0.5 mg L-1) for the first three runoff events and highest (approximately 1-1.5 mg L-1) at 168 HAT due to the time elapsed for conversion of ammonia to nitrate. Nitrate N mass was highest at the 4 and 24 HAT events and stepwise increases with rate were evident at 24 HAT. Total P transported for all events was 15.6 and 13.8% of that added for the two non-zero rates, respectively. Total nitrate N transported was 1.5 and 0.9% of that added for the two rates, respectively. Results indicate that turfgrass management should include applying minimum amounts of irrigation after fertilizer application and avoiding application before intense rain or when soil is very moist.

Application of step-drawdown test for planning agricultural groundwater well maintenance in S. Korea

NASA Astrophysics Data System (ADS)

Song, Sung-Ho; Lee, Byung-Sun

2015-04-01

Well efficiency decreases with time after development and the pumping rate is reduced sharply at a certain point. However, the rapid decrease of the efficiency definitely depends upon the physical characteristics of the aquifer, chemical properties of groundwater, pore clogging by adsorptive/precipitable materials, and use of groundwater well. In general, it is expected that an adequate and ongoing maintenance for the well is effective in extension of operating periods because major maintenance frequency requirement at municipal wells placed in the crystalline rock aquifer is known to be relatively longer. The proportion of agricultural wells (583,748) against the total groundwater ones (1,380,715) is 42.3% in 2011, S. Korea. Groundwater use accounts for 1.9 billion m3/year which indicates 48.9% of total amount available groundwater resources. Approximate 69% of the total agricultural public wells placed in crystalline rock aquifer have passed more than 10 years after development. In this study, the increase of well efficiency before and after the well disinfection/cleaning for agricultural groundwater wells in the mountains, plains, and coastal aquifer with the data of step-drawdown test was evaluated, respectively. With the concept of critical yield, the increase of available amount of groundwater was quantitatively analyzed after treatment. From the results, well efficiency increased approximately 1.5 to 4 times depending on pumping rate when the proper disinfection/cleaning methods to the wells were applied. In addition, it showed that the pumping rate of approximate 4-8% with the critical yield from step-drawdown test increased and these effects were the highest in wells which are more than 10 years elapsed. Therefore, it would be concluded that the well disinfection/cleaning methods for the purpose of increasing the efficiency are more effective for the wells that are older than 10 years.

wFReDoW: A Cloud-Based Web Environment to Handle Molecular Docking Simulations of a Fully Flexible Receptor Model

PubMed Central

De Paris, Renata; Frantz, Fábio A.; Norberto de Souza, Osmar; Ruiz, Duncan D. A.

2013-01-01

Molecular docking simulations of fully flexible protein receptor (FFR) models are coming of age. In our studies, an FFR model is represented by a series of different conformations derived from a molecular dynamic simulation trajectory of the receptor. For each conformation in the FFR model, a docking simulation is executed and analyzed. An important challenge is to perform virtual screening of millions of ligands using an FFR model in a sequential mode since it can become computationally very demanding. In this paper, we propose a cloud-based web environment, called web Flexible Receptor Docking Workflow (wFReDoW), which reduces the CPU time in the molecular docking simulations of FFR models to small molecules. It is based on the new workflow data pattern called self-adaptive multiple instances (P-SaMIs) and on a middleware built on Amazon EC2 instances. P-SaMI reduces the number of molecular docking simulations while the middleware speeds up the docking experiments using a High Performance Computing (HPC) environment on the cloud. The experimental results show a reduction in the total elapsed time of docking experiments and the quality of the new reduced receptor models produced by discarding the nonpromising conformations from an FFR model ruled by the P-SaMI data pattern. PMID:23691504

Asymmetric lipid-polymer particles (LIPOMER) by modified nanoprecipitation: role of non-solvent composition.

PubMed

Jindal, Anil B; Devarajan, Padma V

2015-07-15

Asymmetric lipid polymer nanostructures (LIPOMER) comprising glyceryl monostearate (GMS) as lipid and Gantrez AN 119 (Gantrez) as polymer, revealed enhanced splenic accumulation. In the present paper, we attempt to explain the formation of asymmetric GMS LIPOMER using real time imaging. Particles were prepared by precipitation under static conditions using different non-solvent phase compositions. The process was video recorded and the videos converted to time elapsed images using the FFmpeg 0.10.2 software at 25 frames/sec. Non-solvent compositions comprising >30% of IPA/Acetone revealed significant stranding of the solvent phase and slower onset of precipitation(2-6s). At lower concentrations of IPA and acetone, and in non-solvent compositions comprising ethanol/water the stranding phenomenon was not evident. Further, rapid precipitation(<1 s) was evident. Nanoprecipitation based on the Marangoni effect is a result of diffusion stranding, interfacial turbulence, and mass transfer of solvent and non-solvent resulting in solute precipitation. Enhanced diffusion stranding favored by high interaction of GMS and Gantrez(low ΔPol), and the low solubility parameter(Δδtotal) and high mixing enthalpy(ΔHM) of GMS in IPA resulted in droplets with random shapes analogous to an amoeba with pseudopodia, which on precipitation formed asymmetric particles. Asymmetric particles could be readily designed through appropriate selection of solutes and non-solvent phase by modified nanoprecipitation. Copyright © 2015 Elsevier B.V. All rights reserved.

Flight Test of a 40-Foot Nominal-Diameter Disk-Gap-Band Parachute Deployed at a Mach Number of 1.91 and a Dynamic Pressure of 11.6 Pounds per Square Foot

NASA Technical Reports Server (NTRS)

Eckstrom, Clinton V.; Preisser, John S.

1968-01-01

A 40-foot (12.2 meter) nominal-diameter disk-gap-band parachute was flight tested as part of the NASA Supersonic Planetary Entry Decelerator Program (SPED-I). The test parachute was ejected by a deployment mortar from an instrumented payload at an altitude of 140,000 feet (42.5 kilometers). The payload was at a Mach number of 1.91 and the dynamic pressure was 11.6 pounds per square foot (555 newtons per square meter) at the time the parachute deployment mortar was fired. The parachute reached suspension line stretch in 0.43 second with a resultant snatch force loading of 1990 pounds (8850 newtons). The maximum parachute opening load of 6500 pounds (28,910 newtons) came 0.61 second later at a total elapsed time from mortar firing of 1.04 seconds. The first full inflation occurred at 1.12 seconds and stable inflation was achieved at approximately 1.60 seconds. The parachute had an average axial-force coefficient of 0.53 during the deceleration period. During the steady-state descent portion of the flight test, the average effective drag coefficient was also 0.53 and pitch-yaw oscillations of the canopy averaged less than 10 degrees in the altitude region above 100,000 feet (30.5 meters).

Sustained attention performance during sleep deprivation associates with instability in behavior and physiologic measures at baseline.

PubMed

Chua, Eric Chern-Pin; Yeo, Sing-Chen; Lee, Ivan Tian-Guang; Tan, Luuan-Chin; Lau, Pauline; Cai, Shiwei; Zhang, Xiaodong; Puvanendran, Kathiravelu; Gooley, Joshua J

2014-01-01

To identify baseline behavioral and physiologic markers that associate with individual differences in sustained attention during sleep deprivation. In a retrospective study, ocular, electrocardiogram, and electroencephalogram (EEG) measures were compared in subjects who were characterized as resilient (n = 15) or vulnerable (n = 15) to the effects of total sleep deprivation on sustained attention. Chronobiology and Sleep Laboratory, Duke-NUS Graduate Medical School Singapore. Healthy volunteers aged 22-32 years from the general population. Subjects were kept awake for at least 26 hours under constant environmental conditions. Every 2 hours, sustained attention was assessed using a 10-minute psychomotor vigilance task (PVT). During baseline sleep and recovery sleep, EEG slow wave activity was similar in resilient versus vulnerable subjects, suggesting that individual differences in vulnerability to sleep loss were not related to differences in homeostatic sleep regulation. Rather, irrespective of time elapsed since wake, subjects who were vulnerable to sleep deprivation exhibited slower and more variable PVT response times, lower and more variable heart rate, and higher and more variable EEG spectral power in the theta frequency band (6.0-7.5 Hz). Performance decrements in sustained attention during sleep deprivation associate with instability in behavioral and physiologic measures at baseline. Small individual differences in sustained attention that are present at baseline are amplified during prolonged wakefulness, thus contributing to large between-subjects differences in performance and sleepiness.

Flight Test of 31.2 Diameter Modified Ringsail Parachute Deployed at Mach 1.39, Dynamic Pressure 11 Pounds per Square Foot

NASA Technical Reports Server (NTRS)

Preisser, John S.; Eckstrom, Clinton V.; Murrow, Harold N.

1967-01-01

A 31.2-foot (9.51 meter) nominal diameter (reference area 764 ft(exp 2) (71.0 m(exp 2)) ringsail parachute modified to provide 15-percent geometric porosity was flight tested while attached to a 201-pound mass (91.2 kilogram) instrumented payload as part of the rocket launch portion of the NASA Planetary Entry Parachute Program (PEPP). The parachute deployment was initiated by the firing of a mortar at a Mach number of 1.39 and a dynamic pressure of 11.0 lb/ft(exp 2) (527 newtons/m(exp 2)) at an altitude of 122,500 feet (37.3 kilometers). The parachute deployed to suspension-line stretch (snatch force) in 0.35 second, and 0.12 second later the drag force increase associated with parachute inflation began. The parachute inflated in 0.24 second to the full-open condition for a total elapsed opening time of 0.71 second. The maximum opening load of 3970 pounds (17,700 newtons) came at the time the parachute was just fully opened. During the deceleration period, the parachute exhibited an average drag coefficient of 0.52 and oscillations of the parachute canopy were less than 5 degrees. During the steady-state terminal descent portion of the test period, the average effective drag coefficient (based on vertical descent velocity) was 0.52.

High resolution data acquisition

DOEpatents

Thornton, G.W.; Fuller, K.R.

1993-04-06

A high resolution event interval timing system measures short time intervals such as occur in high energy physics or laser ranging. Timing is provided from a clock, pulse train, and analog circuitry for generating a triangular wave synchronously with the pulse train (as seen in diagram on patent). The triangular wave has an amplitude and slope functionally related to the time elapsed during each clock pulse in the train. A converter forms a first digital value of the amplitude and slope of the triangle wave at the start of the event interval and a second digital value of the amplitude and slope of the triangle wave at the end of the event interval. A counter counts the clock pulse train during the interval to form a gross event interval time. A computer then combines the gross event interval time and the first and second digital values to output a high resolution value for the event interval.

High resolution data acquisition

DOEpatents

Thornton, Glenn W.; Fuller, Kenneth R.

1993-01-01

A high resolution event interval timing system measures short time intervals such as occur in high energy physics or laser ranging. Timing is provided from a clock (38) pulse train (37) and analog circuitry (44) for generating a triangular wave (46) synchronously with the pulse train (37). The triangular wave (46) has an amplitude and slope functionally related to the time elapsed during each clock pulse in the train. A converter (18, 32) forms a first digital value of the amplitude and slope of the triangle wave at the start of the event interval and a second digital value of the amplitude and slope of the triangle wave at the end of the event interval. A counter (26) counts the clock pulse train (37) during the interval to form a gross event interval time. A computer (52) then combines the gross event interval time and the first and second digital values to output a high resolution value for the event interval.

Epidemiologic study of vinyl chloride workers: mortality through December 31, 1972.

PubMed Central

Cooper, W C

1981-01-01

A population of 10,173 men, employed in 37 plants, was identified as having worked for at least one year in jobs involving probable exposure to vinyl chloride monomer (VCM) prior to January 1, 1973. Of the 9677 men whose vital status was determined, 707 were known to have died. For 699, death certificates were obtained. The standardized mortality ratio (SMR) for all causes was 89, that for all malignancies was 104. The only type of malignancy found in significant excess was in the category of malignant neoplasms of the brain and other parts of the nervous system; 12 deaths occurred where 5.9 were expected, for an adjusted SMR of 203. There were slight but inconclusive upward trends in all malignancies, and for malignancies of the respiratory tract, digestive tract, and central nervous system associated with reported levels of maximum exposure to VCM. When groups in whom less than 20 years had elapsed from the first exposure were compared with those with 20 or more elapsed years, and 25 or more elapsed years, no significantly different SMR's were detected for major primary sites of malignancy. Plans for an updated study of mortality, to include deaths in the period 1973-1979 are briefly discussed. PMID:7199425

Photomosaics and logs of trenches on the San Andreas Fault, Thousand Palms Oasis, California

USGS Publications Warehouse

Fumal, Thomas E.; Frost, William T.; Garvin, Christopher; Hamilton, John C.; Jaasma, Monique; Rymer, Michael J.

2004-01-01

We present photomosaics and logs of the walls of trenches excavated for a paleoseismic study at Thousand Palms Oasis (Fig. 1). The site is located on the Mission Creek strand of the San Andreas fault zone, one of two major active strands of the fault in the Indio Hills along the northeast margin of the Coachella Valley (Fig. 2). The Coachella Valley section is the most poorly understood major part of the San Andreas fault with regard to slip rate and timing of past large-magnitude earthquakes, and therefore earthquake hazard. No large earthquakes have occurred for more than three centuries, the longest elapsed time for any part of the southern San Andreas fault. In spite of this, the Working Group on California Earthquake Probabilities (1995) assigned the lowest 30-year conditional probability on the southern San Andreas fault to the Coachella Valley. Models of the behavior of this part of the fault, however, have been based on very limited geologic data. The Thousand Palms Oasis is an attractive location for paleoseismic study primarily because of the well-bedded late Holocene sedimentary deposits with abundant layers of organic matter for radiocarbon dating necessary to constrain the timing of large prehistoric earthquakes. Previous attempts to develop a chronology of paleoearthquakes for the region have been hindered by the scarcity of in-situ 14C-dateable material for age control in this desert environment. Also, the fault in the vicinity of Thousand Palms Oasis consists of a single trace that is well expressed, both geomorphically and as a vegetation lineament (Figs. 2, 3). Results of our investigations are discussed in Fumal et al. (2002) and indicate that four and probably five surface-rupturing earthquakes occurred along this part of the fault during the past 1200 years. The average recurrence time for these earthquakes is 215 ± 25 years, although interevent times may have been as short as a few decades or as long as 400 years. Thus, although the elapsed time since the most recent earthquake, about 320 years, is about 50% longer than the average recurrence time, it is not necessarily unprecedented.

Modeling and identifying the sources of radiocesium contamination in separate sewerage systems.

PubMed

Pratama, Mochamad Adhiraga; Yoneda, Minoru; Yamashiki, Yosuke; Shimada, Yoko; Matsui, Yasuto

2018-05-01

The Fukushima Dai-ichi nuclear power plant accident released radiocesium in large amounts. The released radionuclides contaminated much of the surrounding environment, including sewers in urban areas of Fukushima prefecture. In this study we attempted to identify and quantify the sources of radiocesium contamination in separate sewerage systems and developed a compartment model based on the Radionuclide Migration in Urban Environments and Drainage Systems (MUD) model. Measurements of the time-dependent radiocesium concentration in sewer sludge combined with meteorological, demographic, and radiocesium dietary intake data indicated that rainfall-derived inflow and infiltration (RDII) and human excretion were the chief contributors of radiocesium contamination in a separate sewerage system. The quantities of contamination derived from RDII and human excretion were calculated and used in the modified MUD model to simulate radiocesium contamination in sewers in three urban areas in Fukushima prefecture: Fukushima, Koriyama, and Nihonmatsu Cities. The Nash efficiency coefficient (0.88-0.92) and determination coefficient (0.89-0.93) calculated in an evaluation of our compartment model indicated that the model produced satisfactory results. We also used the model to estimate the total volume of sludge with radiocesium concentrations in excess of the clearance level, based on the number of months elapsed after the accident. Estimations by our model suggested that wastewater treatment plants (WWTPs) in Fukushima, Koriyama, and Nihonmatsu generated about 1,750,000m 3 of radioactive sludge in total, a level in good agreement with the real data. Copyright © 2017 Elsevier B.V. All rights reserved.

Global Food Security Index Studies and Satellite Information

NASA Astrophysics Data System (ADS)

Medina, T. A.; Ganti-Agrawal, S.; Joshi, D.; Lakhankar, T.

2017-12-01

Food yield is equal to the total crop harvest per unit cultivated area. During the elapsed time of germination and frequent harvesting, both human and climate related effects determine a country's' contribution towards global food security. Each country across the globe's annual income per capita was collected to then determine nine countries for further studies. For a location to be chosen, its income per capita needed to be considered poor, uprising or wealthy. Both physical land cover and regional climate helped categorize potential parameters thought to be studied. Once selected, Normalized Difference Vegetation Index (NDVI) data was collected for Ethiopia, Liberia, Indonesia, United States, Norway, Russia, Kuwait and Saudi Arabia over the recent 16 years for approximately every 16 days starting from early in the year 2000. Software languages such as Geographic Information System (GIS), MatLab and Excel were used to determine how population size, income and deforestation directly determines agricultural yields. Because of high maintenance requirements for large harvests when forest areas are cleared, they often have a reduction in soil quality, requiring fertilizer use to produce sufficient crop yields. Total area and vegetation index of each country is to be studied, to determine crop and deforestation percentages. To determine how deforestation impacts future income and crop yield predictions of each country studied. By using NDVI results a parameter is to be potentially found that will help define an index, to create an equation that will determine a country's annual income and ability to provide for their families and themselves.

Dental Erosion and Caries Status of Chinese University Students.

PubMed

Chu, Chun Hung; Ng, Alice; Chau, Alex Man Him; Lo, Edward Chin Man

2015-01-01

To describe the prevalence and severity of dental erosion and caries experience of Chinese university students in Hong Kong. First-year Chinese students were invited to attend a dental clinic at a university campus in Hong Kong during their freshman orientation. A questionnaire was used to investigate the potential factors affecting their dental status, including sociodemographic factors, toothbrushing habits, dietary habits (consumption of sugary drinks), time elapsed since last dental check-up and self-perceived dental erosion status. Three calibrated dentists performed the clinical examinations. Dental erosion was evaluated using the modified Basic Erosive Wear Examination (BEWE) and dental caries experience was measured using the DMFT index. In total, 600 participants aged 18-21 were examined and 44% showed some signs of dental erosion (maximum BEWE > 0). Severe dental erosion (BEWE = 3) was found in 1% of the adults. Many (69%) had caries experience (DMFT > 0); their mean DMFT score was 2.5 ± 2.7 (± SD). The total BEWE scores were found to be associated with age and self-perception of tooth misalignment. No correlation was found between BEWE score and dietary habits, oral hygiene practices or self-perceived dental erosion status. Females, those whose last dental check-up was more than a year ago and those who perceived having dental decay or tooth wear had higher caries experience. Nearly half of the Chinese Hong Kong university students had signs of dental erosion, but very few showed signs of severe erosion. Caries experience was widespread but not high.

Long-Term Memory: A Natural Mechanism for the Clustering of Extreme Events and Anomalous Residual Times in Climate Records

NASA Astrophysics Data System (ADS)

Bunde, Armin; Eichner, Jan F.; Kantelhardt, Jan W.; Havlin, Shlomo

2005-01-01

We study the statistics of the return intervals between extreme events above a certain threshold in long-term persistent records. We find that the long-term memory leads (i)to a stretched exponential distribution of the return intervals, (ii)to a pronounced clustering of extreme events, and (iii)to an anomalous behavior of the mean residual time to the next event that depends on the history and increases with the elapsed time in a counterintuitive way. We present an analytical scaling approach and demonstrate that all these features can be seen in long climate records. The phenomena should also occur in heartbeat records, Internet traffic, and stock market volatility and have to be taken into account for an efficient risk evaluation.

Digital control system for space structure dampers

NASA Technical Reports Server (NTRS)

Haviland, J. K.

1985-01-01

A digital controller was developed using an SKD-51 System Design Kit, which incorporates an 8031 microcontroller. The necessary interfaces were installed in the wire wrap area of the SKD-51 and a pulse width modulator was developed to drive the coil of the actuator. Also, control equations were developed, using floating-point arithmetic. The design of the digital control system is emphasized, and it is shown that, provided certain rules are followed, an adequate design can be achieved. It is recommended that the so-called w-plane design method be used, and that the time elapsed before output of the up-dated coil-force signal be kept as small as possible. However, the cycle time for the controller should be watched carefully, because very small values for this time can lead to digital noise.

Method of noncontacting ultrasonic process monitoring

DOEpatents

Garcia, Gabriel V.; Walter, John B.; Telschow, Kenneth L.

1992-01-01

A method of monitoring a material during processing comprising the steps of (a) shining a detection light on the surface of a material; (b) generating ultrasonic waves at the surface of the material to cause a change in frequency of the detection light; (c) detecting a change in the frequency of the detection light at the surface of the material; (d) detecting said ultrasonic waves at the surface point of detection of the material; (e) measuring a change in the time elapsed from generating the ultrasonic waves at the surface of the material and return to the surface point of detection of the material, to determine the transit time; and (f) comparing the transit time to predetermined values to determine properties such as, density and the elastic quality of the material.

Brownian dynamics simulations on a hypersphere in 4-space

NASA Astrophysics Data System (ADS)

Nissfolk, Jarl; Ekholm, Tobias; Elvingson, Christer

2003-10-01

We describe an algorithm for performing Brownian dynamics simulations of particles diffusing on S3, a hypersphere in four dimensions. The system is chosen due to recent interest in doing computer simulations in a closed space where periodic boundary conditions can be avoided. We specifically address the question how to generate a random walk on the 3-sphere, starting from the solution of the corresponding diffusion equation, and we also discuss an efficient implementation based on controlled approximations. Since S3 is a closed manifold (space), the average square displacement during a random walk is no longer proportional to the elapsed time, as in R3. Instead, its time rate of change is continuously decreasing, and approaches zero as time becomes large. We show, however, that the effective diffusion coefficient can still be obtained from the time dependence of the square displacement.

The Potential Influence of Bumble Bee Visitation on Foraging Behaviors and Assemblages of Honey Bees on Squash Flowers in Highland Agricultural Ecosystems

PubMed Central

Xie, Zhenghua; Pan, Dongdong; Teichroew, Jonathan; An, Jiandong

2016-01-01

Bee species interactions can benefit plant pollination through synergistic effects and complementary effects, or can be of detriment to plant pollination through competition effects by reducing visitation by effective pollinators. Since specific bee interactions influence the foraging performance of bees on flowers, they also act as drivers to regulate the assemblage of flower visitors. We selected squash (Cucurbita pepo L.) and its pollinators as a model system to study the foraging response of honey bees to the occurrence of bumble bees at two types of sites surrounded by a high amount of natural habitats (≥ 58% of land cover) and a low amount of natural habitats (≤ 12% of land cover) in a highland agricultural ecosystem in China. At the individual level, we measured the elapsed time from the departure of prior pollinator(s) to the arrival of another pollinator, the selection of honey bees for flowers occupied by bumble bees, and the length of time used by honey bees to explore floral resources at the two types of sites. At the community level, we explored the effect of bumble bee visitation on the distribution patterns of honey bees on squash flowers. Conclusively, bumble bee visitation caused an increase in elapsed time before flowers were visited again by a honey bee, a behavioral avoidance by a newly-arriving honey bee to select flowers occupied by bumble bees, and a shortened length of time the honey bee takes to examine and collect floral resources. The number of overall bumble bees on squash flowers was the most important factor explaining the difference in the distribution patterns of honey bees at the community level. Furthermore, decline in the number of overall bumble bees on the squash flowers resulted in an increase in the number of overall honey bees. Therefore, our study suggests that bee interactions provide an opportunity to enhance the resilience of ecosystem pollination services against the decline in pollinator diversity. PMID:26765140

The Potential Influence of Bumble Bee Visitation on Foraging Behaviors and Assemblages of Honey Bees on Squash Flowers in Highland Agricultural Ecosystems.

PubMed

Xie, Zhenghua; Pan, Dongdong; Teichroew, Jonathan; An, Jiandong

2016-01-01

Bee species interactions can benefit plant pollination through synergistic effects and complementary effects, or can be of detriment to plant pollination through competition effects by reducing visitation by effective pollinators. Since specific bee interactions influence the foraging performance of bees on flowers, they also act as drivers to regulate the assemblage of flower visitors. We selected squash (Cucurbita pepo L.) and its pollinators as a model system to study the foraging response of honey bees to the occurrence of bumble bees at two types of sites surrounded by a high amount of natural habitats (≥ 58% of land cover) and a low amount of natural habitats (≤ 12% of land cover) in a highland agricultural ecosystem in China. At the individual level, we measured the elapsed time from the departure of prior pollinator(s) to the arrival of another pollinator, the selection of honey bees for flowers occupied by bumble bees, and the length of time used by honey bees to explore floral resources at the two types of sites. At the community level, we explored the effect of bumble bee visitation on the distribution patterns of honey bees on squash flowers. Conclusively, bumble bee visitation caused an increase in elapsed time before flowers were visited again by a honey bee, a behavioral avoidance by a newly-arriving honey bee to select flowers occupied by bumble bees, and a shortened length of time the honey bee takes to examine and collect floral resources. The number of overall bumble bees on squash flowers was the most important factor explaining the difference in the distribution patterns of honey bees at the community level. Furthermore, decline in the number of overall bumble bees on the squash flowers resulted in an increase in the number of overall honey bees. Therefore, our study suggests that bee interactions provide an opportunity to enhance the resilience of ecosystem pollination services against the decline in pollinator diversity.

Multifractal detrended fluctuation analysis of intensity time series of photons scattered by tracer particles within a polymeric gel

NASA Astrophysics Data System (ADS)

Telesca, Luciano; Haro-Pérez, Catalina; Moreno-Torres, L. Rebeca; Ramirez-Rojas, Alejandro

2018-01-01

Some properties of spatial confinement of tracer colloidal particles within polyacrylamide dispersions are studied by means of the well-known dynamic light scattering (DLS) technique. DLS allows obtaining sequences of elapsed times of scattered photons. In this work, the aqueous polyacrylamide dispersion has no crosslinking and the volume fraction occupied by the tracer particles is 0.02 %. Our experimental setup provides two sequences of photons scattered by the same scattering volume that corresponds to two simultaneous experiments (Channel A and Channel B). By integration of these sequences, the intensity time series are obtained. We find that both channels are antipersistent with Hurst exponent, H ∼0.43 and 0.36, respectively. The antipersistence of the intensity time series indicates a subdiffusive dynamics of the tracers in the polymeric network, which is in agreement with the time dependence of the tracer's mean square displacement.

Transcranial Photoacoustic Measurements of Cold-Injured Brains in Rats

NASA Astrophysics Data System (ADS)

Ueda, Yoshinori; Sato, Shunichi; Hasegawa, Makoto; Nawashiro, Hiroshi; Saitoh, Daizoh; Shima, Katsuji; Ashida, Hiroshi; Obara, Minoru

2005-09-01

We performed transcranial photoacoustic measurements of cold-injured brains in rats. Before inducing injury, a signal peak was observed at two locations corresponding to the surfaces of the skull and brain, while after injury, a third peak appeared at a location corresponding to the back surface of the skull; the third peak was found to be caused by subdural hematoma. The signal peak for the brain surface shifted to a deeper region with elapse of time after injury, indicating deformation of the brain. These findings suggest that small hemorrhage and morphological change of the brain can be transcranially detected by photoacoustic measurement.

[Formation of endogenous pyrogen by mononuclear phagocytes].

PubMed

Agasarov, L G

1980-03-01

Incubation of alveolar macrophages of rabbits and peritoneal macrophages of the abdominal cavity washing of albino mice does not lead to endogenous pyrogen release. Peritoneal macrophages obtained after peritoneal administration to mice of thioglycollate, glycogen or heterologous blood cells do not discharge pyrogen either during incubation without additional stimulation. Macrophages isolated after intraperitoneal administration of heterologous blood cells do not exhibit pyrogenic activity possibly because of a long period of time elapsed after phagocytosis of foreign agents. The triggering of pyrogen formation by macrophages can be effected by means of in vitro phagocytosis of corpuscular particles: staphylococci or heterologous blood cells.

Oxygen Mass Transfer Coefficient (k sub L a’) Consideration for Scale-Up Fermentation Systems at the Biotechnology Laboratory U.S. Army Edgewood Chemical Biological Center

DTIC Science & Technology

2011-02-01

30 °C Stock vials were prepared following standard microbial protocol. A single colony from the overnight nutrient agar plate was inoculated into...500-mL seed cultures were prepared by inoculating with 2 vials of frozen stock and incubating at 30 °C and 200 rpm until the OD reached approximately...and OD profiles vs. elapsed fermentation time ( EFT ) from 20- and 1000-L scales are shown in Figure 9. In both runs, no DO limitation was apparent, and

Determination of single-kidney glomerular filtration rate (GFR) with CT urography versus renal dynamic imaging Gates method.

PubMed

You, Shan; Ma, XianWu; Zhang, ChangZhu; Li, Qiang; Shi, WenWei; Zhang, Jing; Yuan, XiaoDong

2018-03-01

To present a single-kidney CT-GFR measurement and compare it with the renal dynamic imaging Gates-GFR. Thirty-six patients with hydronephrosis referred for CT urography and 99mTc-DTPA renal dynamic imaging were prospectively included. Informed consent was obtained from all patients. The CT urography protocol included non-contrast, nephrographic, and excretory phase imaging. The total CT-GFR was calculated by dividing the CT number increments of the total urinary system between the nephrographic and excretory phase by the products of iodine concentration in the aorta and the elapsed time, then multiplied by (1- Haematocrit). The total CT-GFR was then split into single-kidney CT-GFR by a left and right kidney proportionality factor. The results were compared with single-kidney Gates-GFR by using paired t-test, correlation analysis, and Bland-Altman plots. Paired difference between single-kidney CT-GFR (45.02 ± 13.91) and single-kidney Gates-GFR (51.21 ± 14.76) was 6.19 ± 5.63 ml/min, p<0.001, demonstrating 12.1% systematic underestimation with ±11.03 ml/min (±21.5%) measurement deviation. A good correlation was revealed between both measurements (r=0.87, p<0.001). The proposed single-kidney CT-GFR correlates and agrees well with the reference standard despite a systematic underestimation, therefore it could be a one-stop-shop for evaluating urinary tract morphology and split renal function. • A new CT method can assess split renal function • Only using images from CT urography and the value of haematocrit • A one-stop-shop CT technique without additional radiation dose.

Estimating the returns to UK publicly funded cancer-related research in terms of the net value of improved health outcomes

PubMed Central

2014-01-01

Background Building on an approach developed to assess the economic returns to cardiovascular research, we estimated the economic returns from UK public and charitable funded cancer-related research that arise from the net value of the improved health outcomes. Methods To assess these economic returns from cancer-related research in the UK we estimated: 1) public and charitable expenditure on cancer-related research in the UK from 1970 to 2009; 2) net monetary benefit (NMB), that is, the health benefit measured in quality adjusted life years (QALYs) valued in monetary terms (using a base-case value of a QALY of GB£25,000) minus the cost of delivering that benefit, for a prioritised list of interventions from 1991 to 2010; 3) the proportion of NMB attributable to UK research; 4) the elapsed time between research funding and health gain; and 5) the internal rate of return (IRR) from cancer-related research investments on health benefits. We analysed the uncertainties in the IRR estimate using sensitivity analyses to illustrate the effect of some key parameters. Results In 2011/12 prices, total expenditure on cancer-related research from 1970 to 2009 was £15 billion. The NMB of the 5.9 million QALYs gained from the prioritised interventions from 1991 to 2010 was £124 billion. Calculation of the IRR incorporated an estimated elapsed time of 15 years. We related 17% of the annual NMB estimated to be attributable to UK research (for each of the 20 years 1991 to 2010) to 20 years of research investment 15 years earlier (that is, for 1976 to 1995). This produced a best-estimate IRR of 10%, compared with 9% previously estimated for cardiovascular disease research. The sensitivity analysis demonstrated the importance of smoking reduction as a major source of improved cancer-related health outcomes. Conclusions We have demonstrated a substantive IRR from net health gain to public and charitable funding of cancer-related research in the UK, and further validated the approach that we originally used in assessing the returns from cardiovascular research. In doing so, we have highlighted a number of weaknesses and key assumptions that need strengthening in further investigations. Nevertheless, these cautious estimates demonstrate that the returns from past cancer research have been substantial, and justify the investments made during the period 1976 to 1995. PMID:24930803

Estimating the returns to United Kingdom publicly funded musculoskeletal disease research in terms of net value of improved health outcomes.

PubMed

Glover, Matthew; Montague, Erin; Pollitt, Alexandra; Guthrie, Susan; Hanney, Stephen; Buxton, Martin; Grant, Jonathan

2018-01-10

Building on an approach applied to cardiovascular and cancer research, we estimated the economic returns from United Kingdom public- and charitable-funded musculoskeletal disease (MSD) research that arise from the net value of the improved health outcomes in the United Kingdom. To calculate the economic returns from MSD-related research in the United Kingdom, we estimated (1) the public and charitable expenditure on MSD-related research in the United Kingdom between 1970 and 2013; (2) the net monetary benefit (NMB), derived from the health benefit in quality adjusted life years (QALYs) valued in monetary terms (using a base-case value of a QALY of £25,000) minus the cost of delivering that benefit, for a prioritised list of interventions from 1994 to 2013; (3) the proportion of NMB attributable to United Kingdom research; and (4) the elapsed time between research funding and health gain. The data collected from these four key elements were used to estimate the internal rate of return (IRR) from MSD-related research investments on health benefits. We analysed the uncertainties in the IRR estimate using a one-way sensitivity analysis. Expressed in 2013 prices, total expenditure on MSD-related research from 1970 to 2013 was £3.5 billion, and for the period used to estimate the rate of return, 1978-1997, was £1.4 billion. Over the period 1994-2013 the key interventions analysed produced 871,000 QALYs with a NMB of £16 billion, allowing for the net NHS costs resulting from them and valuing a QALY at £25,000. The proportion of benefit attributable to United Kingdom research was 30% and the elapsed time between funding and impact of MSD treatments was 16 years. Our best estimate of the IRR from MSD-related research was 7%, which is similar to the 9% for CVD and 10% for cancer research. Our estimate of the IRR from the net health gain to public and charitable funding of MSD-related research in the United Kingdom is substantial, and justifies the research investments made between 1978 and 1997. We also demonstrated the applicability of the approach previously used in assessing the returns from cardiovascular and cancer research. Inevitably, with a study of this kind, there are a number of important assumptions and caveats that we highlight, and these can inform future research.

Apparatus and method for maximizing power delivered by a photovoltaic array

DOEpatents

Muljadi, Eduard; Taylor, Roger W.

1998-01-01

A method and apparatus for maximizing the electric power output of a photovoltaic array connected to a battery where the voltage across the photovoltaic array is adjusted through a range of voltages to find the voltage across the photovoltaic array that maximizes the electric power generated by the photovoltaic array and then is held constant for a period of time. After the period of time has elapsed, the electric voltage across the photovoltaic array is again adjusted through a range of voltages and the process is repeated. The electric energy and the electric power generated by the photovoltaic array is delivered to the battery which stores the electric energy and the electric power for later delivery to a load.

Wavepacket dynamics in one-dimensional system with long-range correlated disorder

NASA Astrophysics Data System (ADS)

Yamada, Hiroaki S.

2018-03-01

We numerically investigate dynamical property in the one-dimensional tight-binding model with long-range correlated disorder having power spectrum 1 /fα (α: spectrum exponent) generated by Fourier filtering method. For relatively small α <αc (=2) time-dependence of mean square displacement (MSD) of the initially localized wavepacket shows ballistic spread and localizes as time elapses. It is shown that α-dependence of the dynamical localization length determined by the MSD exhibits a simple scaling law in the localization regime for the relatively weak disorder strength W. Furthermore, scaled MSD by the dynamical localization length almost obeys an universal function from the ballistic to the localization regime in the various combinations of the parameters α and W.

Apparatus and method for maximizing power delivered by a photovoltaic array

DOEpatents

Muljadi, E.; Taylor, R.W.

1998-05-05

A method and apparatus for maximizing the electric power output of a photovoltaic array connected to a battery where the voltage across the photovoltaic array is adjusted through a range of voltages to find the voltage across the photovoltaic array that maximizes the electric power generated by the photovoltaic array and then is held constant for a period of time. After the period of time has elapsed, the electric voltage across the photovoltaic array is again adjusted through a range of voltages and the process is repeated. The electric energy and the electric power generated by the photovoltaic array is delivered to the battery which stores the electric energy and the electric power for later delivery to a load. 20 figs.

Catalog of earth photographs from the Apollo-Soyuz test project. [listing cloud photographs and data acquired at time photograph was taken

NASA Technical Reports Server (NTRS)

El-Baz, F. (Editor)

1979-01-01

Information is given on earth photographs obtained by the Apollo astronauts during the Apollo Soyuz Test Project. The data are arranged in three sections. A map index shows the boundaries of each photograph and is used for a quick survey of the coverage for a given geographical area. A tabular index provides the following data: list of photographs by serial number, description of geographic location, latitude and longitude of the center point of the photograph, date when photograph was taken, ground elapsed time, revolution number of Apollo spacecraft, approximate spacecraft altitude, tilt, sun angle, camera, and lens. The photographic index provides same size black and white prints made from the original color negatives.

Analysis of vector wind change with respect to time for Cape Kennedy, Florida: Wind aloft profile change vs. time, phase 1

NASA Technical Reports Server (NTRS)

Adelfang, S. I.

1977-01-01

Wind vector change with respect to time at Cape Kennedy, Florida, is examined according to the theory of multivariate normality. The joint distribution of the four variables represented by the components of the wind vector at an initial time and after a specified elapsed time is hypothesized to be quadravariate normal; the fourteen statistics of this distribution, calculated from fifteen years of twice daily Rawinsonde data are presented by monthly reference periods for each month from 0 to 27 km. The hypotheses that the wind component changes with respect to time is univariate normal, the joint distribution of wind component changes is bivariate normal, and the modulus of vector wind change is Rayleigh, has been tested by comparison with observed distributions. Statistics of the conditional bivariate normal distributions of vector wind at a future time given the vector wind at an initial time are derived. Wind changes over time periods from one to five hours, calculated from Jimsphere data, are presented.

Semireal Time Monitoring Of The Functional Movements Of The Mandible

NASA Astrophysics Data System (ADS)

Isaacson, Robert J.; Baumrind, Sheldon; Curry, Sean; Molthen, Robert A.

1983-07-01

Many branches of dental practice would benefit from the availability of a relatively accurate, precise, and efficient method for monitoring the movements of the human mandible during function. Mechanical analog systems have been utilized in the past but these are difficult to quantify, have limited accuracy due to frictional resistance of the components, and contain information only on the borders of the envelopes of possible movement of the landmarks measured (rather than on the functional paths of the landmarks which lie within their envelopes). Those electronic solutions which have been attempted thus far have been prohibitively expensive and time consuming for clinical use, have had lag times between data acquisition and display, or have involved such restrictions of freedom of motion as to render ambiguous the meaning of the data obtained. We report work aimed at developing a relatively non-restrictive semi-real time acoustical system for monitoring the functional movement of the mandible relative to the rest of the head. A set of three sparking devices is mounted to the mandibular component of a light, relatively non-constraining extra-oral harness and another set of three sparkers is attached to the harness' cranial or skull component. The sparkers are fired sequentially by a multiplexer and the sound associated with each firing is recorded by an array of three or more microphones. Computations based on the known speed of sound are used to evaluate the distances between the sparkers and the microphones. These data can then be transformed by computer to provide numeric or graphic information on the movement of selected mandibular landmarks with respect to the skull. Total elapsed time between the firing of the sparkers and the display of graphic information need not exceed 30-60 seconds using even a relatively modest modern computer.

Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses

PubMed Central

Schafer, Jeffery; Reindel, William; Steffen, Robert; Mosehauer, Gary; Chinn, Joseph

2018-01-01

Background Sustained digital display viewing reduces eye blink frequency and tear film stability. To retain water and preserve a smooth optical surface, contact lens manufacturers have integrated the humectant polyvinylpyrrolidone (PVP) into silicone hydrogel contact lenses. In this study, extended blink time (EBT) was used to assess visual stability over a prolonged blink interval of two PVP-containing silicone hydrogel lenses, samfilcon A (SAM) and senofilcon A (SEN). Materials and methods This randomized, bilateral, masked, crossover study assessed lens performance in ten subjects after 16 hours of wear. EBT, ie, the time elapsed between cessation of blinking and blur-out of a threshold letter on the acuity chart, was measured. At the end of the wear period, subjects reported duration of computer use and rated visual quality (VQ) and comfort while wearing the assigned lens, and the investigator evaluated lens surface wetting characteristics. Each lens was removed and immediately weighed to determine total water content. Results EBTs were 10.42 seconds for SAM and 8.04 seconds for SEN (p = 0.015). Subjective ratings of VQ after 16 hours of wear were 84.6 for SAM and 74.4 for SEN (p = 0.049). Comfort ratings were 85.9 for SAM and 80.2 for SEN (p > 0.05). Median times of computer use were 6–8 hours for both lens types. Post blink, 70.0% of SAM and 30.0% of SEN lenses were completely wet (p = 0.021). Total water content after wear was 43.7% for SAM and 35.5% for SEN (p < 0.001). Conclusion EBT measurement indicated more stable vision with the PVP-containing SAM polymer compared with the PVP-containing SEN polymer. The SAM polymer also demonstrated better surface wetting and maintained higher water content after a prolonged period of wear. EBT can be valuable in assessing vision stability of patients after hours of computer use. PMID:29765195

Beetle succession and diversity between clothed sun-exposed and shaded pig carrion in a tropical dry forest landscape in Southern Mexico.

PubMed

Caballero, Ubaldo; León-Cortés, Jorge L

2014-12-01

Over a 31-day period, the decomposition process, beetle diversity and succession on clothed pig (Sus scrofa L.) carcasses were studied in open (agricultural land) and shaded habitat (secondary forest) in Southern Mexico. The decomposition process was categorised into five stages: fresh, bloated, active decay, advanced decay and remains. Except for the bloated stage, the elapsed time for each decomposition stage was similar between open and shaded habitats, all carcasses reached an advanced decay stage in seven days, and the fifth stage (remains) was not recorded in any carcass during the time of this study. A total of 6344 beetles, belonging to 130 species and 21 families, were collected during the entire decomposition process, and abundances increased from fresh to advanced decay stages. Staphylinidae, Scarabaeidae and Histeridae were taxonomically and numerically dominant, accounting for 61% of the species richness and 87% of the total abundance. Similar numbers of species (87 and 88 species for open and shaded habitats, respectively), levels of diversity and proportions (open 49%; shaded 48%) of exclusive species were recorded at each habitat. There were significantly distinct beetle communities between habitats and for each stage of decomposition. An indicator species analysis ("IndVal") identified six species associated to open habitats, 10 species to shaded habitats and eight species to advanced decay stages. In addition, 23 beetle species are cited for the first time in the forensic literature. These results showed that open and shaded habitats both provide suitable habitat conditions for the carrion beetle diversity with significant differences in community structure and identity of the species associated to each habitat. This research provides the first empirical evidence of beetle ecological succession and diversity on carrion in Mexican agro-pastoral landscapes. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Picosecond timing resolution detection of ggr-photons utilizing microchannel-plate detectors: experimental tests of quantum nonlocality and photon localization

NASA Astrophysics Data System (ADS)

Irby, Victor D.

2004-09-01

The concept and subsequent experimental verification of the proportionality between pulse amplitude and detector transit time for microchannel-plate detectors is presented. This discovery has led to considerable improvement in the overall timing resolution for detection of high-energy ggr-photons. Utilizing a 22Na positron source, a full width half maximum (FWHM) timing resolution of 138 ps has been achieved. This FWHM includes detector transit-time spread for both chevron-stack-type detectors, timing spread due to uncertainties in annihilation location, all electronic uncertainty and any remaining quantum mechanical uncertainty. The first measurement of the minimum quantum uncertainty in the time interval between detection of the two annihilation photons is reported. The experimental results give strong evidence against instantaneous spatial localization of ggr-photons due to measurement-induced nonlocal quantum wavefunction collapse. The experimental results are also the first that imply momentum is conserved only after the quantum uncertainty in time has elapsed (Yukawa H 1935 Proc. Phys. Math. Soc. Japan 17 48).

Time flies faster under time pressure.

PubMed

Rattat, Anne-Claire; Matha, Pauline; Cegarra, Julien

2018-04-01

We examined the effects of time pressure on duration estimation in a verbal estimation task and a production task. In both temporal tasks, participants had to solve mazes in two conditions of time pressure (with or without), and with three different target durations (30 s, 60 s, and 90 s). In each trial of the verbal estimation task, participants had to estimate in conventional time units (minutes and seconds) the amount of time that had elapsed since they started to solve the maze. In the production task, they had to press a key while solving the maze when they thought that the trial's duration had reached a target value. Results showed that in both tasks, durations were judged longer with time pressure than without it. However, this temporal overestimation under time pressure did not increase with the length of the target duration. These results are discussed within the framework of scalar expectancy theory. Copyright © 2018 Elsevier B.V. All rights reserved.

[The importance of memory bias in obtaining age of menarche by recall method in Brazilian adolescents].

PubMed

Castilho, Silvia Diez; Nucci, Luciana Bertoldi; Assuino, Samanta Ramos; Hansen, Lucca Ortolan

2014-06-01

To compare the age at menarche obtained by recall method according to the time elapsed since the event, in order to verify the importance of the recall bias. Were evaluated 1,671 girls (7-18 years) at schools in Campinas-SP regarding the occurrence of menarche by the status quo method (menarche: yes or no) and the recall method (date of menarche, for those who mentioned it). The age at menarche obtained by the status quo method was calculated by logit, which considers the whole group, and the age obtained by the recall method was calculated as the average of the mentioned age at menarche. In this group, the age at menarche was obtained by the difference between the date of the event and the date of birth. Girls who reported menarche (883, 52.8%) were divided into four groups according to the time elapsed since the event. To analyze the results, we used ANOVA and logistic regression for the analysis, with a significance level of 0.05. The age at menarche calculated by logit was 12.14 y/o (95% CI 12.08 to 12.20). Mean ages obtained by recall were: for those who experienced menarche within the previous year 12.26 y/o (±1.14), between > 1-2 years before, 12.29 y (±1.22); between > 2-3 years before, 12.23 y/o (±1.27); and more than 3 years before, 11.55y/o (±1.24), p < 0.001. The age at menarche obtained by the recall method was similar for girls who menstruated within the previous 3 years (and approaches the age calculated by logit); when more than 3 years have passed, the recall bias was significant.

[Performance on the Board of Pediatrics certification examination by the Sociedad Argentina de Pediatría, 2001-2010].

PubMed

Ferrero, Fernando; Yulitta, Horacio; Molina, María Paz; Valli, Raúl

2011-08-01

Professional certification guarantees professional's performance, but the examination tool must be periodically evaluated. To describe the result of the pediatric certifying examination (PCE) of the Sociedad Argentina de Pediatría (SAP), between 2001-2010 analyzing the impact of the age and the elapsed time since the graduation and to describe the performance of training institutions in this period. Cross-section study. Data were obtained from the records of Board of Pediatrics of the SAP. The results of the PCE, were analyzed assessing examination pass rate and training institutions (2001-2010), and age and elapsed time since graduation of the examined professionals (2001-2005). Of 2527 professionals from 138 institutions, 69.6% passed. Those that passed were younger (31.7 ± 4.1 vs. 35.6 ± 6.2 years; p <0.0001) and had less years since graduation (6.3 ± 4.0 vs. 9.0 ± 5.9; p <0.0001) than those who did not pass. The examination pass rate was higher in institutions accredited by SAP (78.4% vs. 48.8%; OR= 3,8 IC95%= 3,1-4,7; p <0.001). The pass rate was significantly higher in institutions with accredited programs for 5 years than those not accredited (78.4% vs. 48.8%, OR= 3.8 95% CI= 3.1 to 4.7, p <0.001). The pass rate at accredited institutions for 3 years (53.7%) and 1 year (48.7%) showed no statistically significant differences with non-accredited institutions. The certifying examination pass rate was 68.5%. Younger professionals with fewer years since graduation, and trained in SAP 5 years accredited programs were significantly more likely to pass the examination.

Analysis Method of Friction Torque and Weld Interface Temperature during Friction Process of Steel Friction Welding

NASA Astrophysics Data System (ADS)

Kimura, Masaaki; Inoue, Haruo; Kusaka, Masahiro; Kaizu, Koichi; Fuji, Akiyoshi

This paper describes an analysis method of the friction torque and weld interface temperature during the friction process for steel friction welding. The joining mechanism model of the friction welding for the wear and seizure stages was constructed from the actual joining phenomena that were obtained by the experiment. The non-steady two-dimensional heat transfer analysis for the friction process was carried out by calculation with FEM code ANSYS. The contact pressure, heat generation quantity, and friction torque during the wear stage were calculated using the coefficient of friction, which was considered as the constant value. The thermal stress was included in the contact pressure. On the other hand, those values during the seizure stage were calculated by introducing the coefficient of seizure, which depended on the seizure temperature. The relationship between the seizure temperature and the relative speed at the weld interface in the seizure stage was determined using the experimental results. In addition, the contact pressure and heat generation quantity, which depended on the relative speed of the weld interface, were solved by taking the friction pressure, the relative speed and the yield strength of the base material into the computational conditions. The calculated friction torque and weld interface temperatures of a low carbon steel joint were equal to the experimental results when friction pressures were 30 and 90 MPa, friction speed was 27.5 s-1, and weld interface diameter was 12 mm. The calculation results of the initial peak torque and the elapsed time for initial peak torque were also equal to the experimental results under the same conditions. Furthermore, the calculation results of the initial peak torque and the elapsed time for initial peak torque at various friction pressures were equal to the experimental results.

Educational effects using a robot patient simulation system for development of clinical attitude.

PubMed

Abe, S; Noguchi, N; Matsuka, Y; Shinohara, C; Kimura, T; Oka, K; Okura, K; Rodis, O M M; Kawano, F

2017-11-01

The aim of this study was to assess the effectiveness of improving the attitude of dental students towards the use of a full-body patient simulation system (SIMROID) compared to the traditional mannequin (CLINSIM) for dental clinical education. The participants were 10 male undergraduate dental students who had finished clinical training in the university hospital 1 year before this study started. They performed a crown preparation on an upper pre-molar tooth using SIMROID and CLINSIM as the practical clinical trials. The elapsed time for preparation was recorded. The taper of the abutment teeth was measured using a 3-dimensional shape-measuring device after this trial. In addition, a self-reported questionnaire was collected that included physical pain, treatment safety and maintaining a clean area for each simulator. Qualitative data analysis of a free format report about SIMROID was performed using text mining analysis. This trial was performed twice at 1-month intervals. The students considered physical pain, treatment safety and a clean area for SIMROID significantly better than that for CLINSIM (P < .01). The elapsed time of preparation in the second practical clinical trial was significantly lower than in the first for SIMROID and CLINSIM (P < .01). However, there were no significant differences between the abutment tapers for both systems. For the text mining analysis, most of the students wrote that SIMROID was similar to real patients. The use of SIMROID was proven to be effective in improving the attitude of students towards patients, thereby giving importance to considerations for actual patients during dental treatment. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Twentieth century demographic changes in cirio and cardón in Baja California, Mexico

USGS Publications Warehouse

Bullock, Stephen H.; Martijena, Nora E.; Webb, Robert H.; Turner, Raymond M.

2005-01-01

Aim  Our purpose was to discern long-term large-scale patterns of survivorship and recruitment of two dominant, charismatic and useful desert plants, cirio [Fouquieriaceae; Fouquieria columnaris (Kell.) Kell. ex Curran] and cardón [Cactaceae; Pachycereus pringlei(S.Watson) Britton & Rose], and to evaluate the effects of physical and human factors. Location  The study included 77 sites distributed over c. 13,200 km2 in the northern Vizcaíno Region of the Sonoran Desert, state of Baja California, México. Method  Censuses used identified individuals (n = 3780 cirio and 2246 cardón) and were based on repeat photography. Time intervals between censuses ranged from 29 to 96 years, ending in 1996–2002. Earlier repetition (1963) of old photographs at 14 sites allowed analysis of temporal variation. The effect of elapsed time was modelled with Weibull functions for survivorship and linear functions for recruitment. To explain the residual variations, we tested categorical and continuous variables related to substrate, geomorphology, climate and geography. Human impacts were weighed with historical and quantitative analysis. Results  Elapsed time accounted for 45% of the variation of survivorship in cirio but only 35% in cardón. The fitted Weibull curves were used to estimate longevity: all-size cohorts of 1000 individuals would die out in 388 (cirio) and 723 years (cardón). Recruitment in cirio was linearly related to time (r2 = 0.71) and averaged < 0.003 year−1 but was less than mortality at 90% of the sites. For cardón, recruitment averaged > 0.005 year−1, was linearly related to time (r2 = 0.66) and was less than mortality at only 33% of the sites. Vital rates were not strongly correlated between mid- and late-century but were mostly similar to the long-term regional rates. Removing the factor of elapsed time, the residual variations showed that survivorship was greater on sites protected from winds for cirio and was less on very coarse soils for cardón. Recruitment increased with latitude in cirio and was greater on southern exposures for both species. The residual variations were not clearly affected, at a regional scale, by other factors thought to be important, including elevation, distance to the Pacific Ocean, geology, slope gradient, soil stability, older vs. young alluvial soils, and soil Ca : Mg and Na : K ratios. Human impacts have been sporadic and heterogeneous but locally strong; our quantitative indices of accessibility did not show regionally significant effects. Blowdown by hurricanes is a sporadic cause of major mortality for cirio but not necessarily for cardón. Main conclusions  At our scales, effects of time outweigh those of substrate, and human impact was scant. Large patterns were pronounced: cirio experienced a prolonged, widespread decline in the 1900s, while cardón fluctuated in different directions and degree among local populations. Cirio was found to be inherently much shorter-lived than cardón. We also suggest that recruitment in cirio was low due to long periods with relatively dry winters that affected the entire region, while spatial heterogeneity of cardón recruitment seemed more related to the variation in summer rains.

Beyond the Time Window of Intravenous Thrombolysis: Standing by or by Stenting?

PubMed Central

Liu, Xinfeng

2012-01-01

Intravenous administration of tissue plasminogen activator within 4.5 h of symptom onset is presently the ‘golden rule’ for treating acute ischemic stroke. However, many patients miss the time window and others reject this treatment due to a long list of contraindications. Mechanical embolectomy has recently progressed as a potential alternative for treating patients beyond the time window for IV thrombolysis. In this paper, recent progress in mechanical embolectomy, angioplasty, and stenting in acute stroke is reviewed. Despite worries concerning the long-term clinical outcomes and increased risk of intracranial hemorrhage, favorable clinical outcomes may be achieved after mechanical embolectomy in carefully selected patients even 4.5 h after stroke onset. Potential steps should be prepared and attempted in these patients whose opportunity for recovery will elapse in a flash. PMID:25187761

Acoustic Neuroma

MedlinePlus

... to two years have elapsed after treatment. The tinnitus (spontaneous noise) so frequently associated with the hearing ... of hearing loss and some high-pitched noise (tinnitus) in his right ear, along with a slight ...

Beta-interferon inhibits cell infection by Trypanosoma cruzi

NASA Technical Reports Server (NTRS)

Kierszenbaum, F.; Sonnenfeld, G.

1984-01-01

Beta interferon has been shown to inhibit the capacity of bloodstream forms of the flagellate Trypanosoma cruzi, the causative agent of Chagas' disease, to associate with and infect mouse peritoneal macrophages and rat heart myoblasts. The inhibitory effect was abrogated in the presence of specific antibodies to the interferon. Pretreatment of the parasites with interferon reduced their infectivity for untreated host cells, whereas pretreament of either type of host cell did not affect the interaction. The effect of interferon on the trypanosomes was reversible; the extent of the inhibitory effect was significantly reduced afer 20 min, and was undetectable after 60 min when macrophages were used as host cells. For the myoblasts, 60 min elapsed before the inhibitory effect began to subside and 120 min elapsed before it became insignificant or undetectable.

A Doubly Stochastic Change Point Detection Algorithm for Noisy Biological Signals.

PubMed

Gold, Nathan; Frasch, Martin G; Herry, Christophe L; Richardson, Bryan S; Wang, Xiaogang

2017-01-01

Experimentally and clinically collected time series data are often contaminated with significant confounding noise, creating short, noisy time series. This noise, due to natural variability and measurement error, poses a challenge to conventional change point detection methods. We propose a novel and robust statistical method for change point detection for noisy biological time sequences. Our method is a significant improvement over traditional change point detection methods, which only examine a potential anomaly at a single time point. In contrast, our method considers all suspected anomaly points and considers the joint probability distribution of the number of change points and the elapsed time between two consecutive anomalies. We validate our method with three simulated time series, a widely accepted benchmark data set, two geological time series, a data set of ECG recordings, and a physiological data set of heart rate variability measurements of fetal sheep model of human labor, comparing it to three existing methods. Our method demonstrates significantly improved performance over the existing point-wise detection methods.

The times are changing: temporal shifts in patterns of fish invasions in central European fresh waters.

PubMed

Rabitsch, W; Milasowszky, N; Nehring, S; Wiesner, C; Wolter, C; Essl, F

2013-01-01

This study examines the invasion history of alien fish species based on exhaustive national data sets on fish invasions of two contiguous central European countries (Germany and Austria). Fifteen alien fish species are currently established in both countries, constituting 14 and 17% of the total freshwater fish fauna of Germany and Austria, respectively. In both countries, six alien species are present, but not established. The status of five alien species in Germany and three species in Austria remains unknown. Accumulation rates of alien fish species have increased in recent decades with >50% of them reported after 1971. North America and Asia were the primary sources of alien fish species in Germany and Austria up to the 1980s, whereas European species of Ponto-Caspian origin dominate now. Fisheries (including aquaculture) and the animal trade were responsible for most earlier introductions, whereas waterways were the main pathway for recent invaders. The extent of the spatial distribution of alien species was positively correlated with residence time, i.e. the time elapsed since the first national record. Different thermal preferences of early invaders (mostly coldwater species) and new invaders (typically warmwater adapted) may benefit the latter in the face of climate change. It is concluded that new challenges for alien fish management arise and that ecosystem-based approaches as endorsed by the E.U. Water Framework Directive (maintaining or restoring good ecological status of rivers and streams) should become the centrepiece of river management in Europe. © 2012 The Authors. Journal of Fish Biology © 2012 The Fisheries Society of the British Isles.

Histologic study of the effects of chemoembolization with preloaded doxorubicin beads in patients with hepatocellular carcinoma.

PubMed

Zurera, L J; Espejo, J J; Lombardo, S; Marchal, T; Muñoz, M C; Canis, M; Montero, J L

2015-01-01

To determine the degree of tumor necrosis in surgical specimens of hepatocellular carcinomas treated with microspheres preloaded with doxorubicin and to analyze the relationship between the degree of necrosis and a) morphologic factors and b) imaging biomarkers. We studied the livers of 21 patients who had undergone selective arterial chemoembolization with DC beads (Biocompatibles, UK) before receiving liver transplants. Imaging techniques detected 43 nodules (mean size, 25 mm). Angiography showed 25 hypervascularized nodules, 12 slightly vascularized nodules, and 6 avascular nodules. A total of 81 hepatocellular carcinomas (mean size, 15 mm) were detected in the specimens: two were capsular and two had vascular infiltration. The mean degree of necrosis after chemoembolization was 39%; necrosis was greater than 60% in 28 hepatocellular carcinomas and less than 60% in 52. The degree of necrosis correlated significantly with the time elapsed between the last chemoembolization treatment and liver transplantation (the degree of necrosis decreased as time increased), with the number of nodules in the specimen, and with capsular infiltration. When imaging techniques detected 1 or 2 nodules, there was a greater probability of achieving greater than 90% necrosis. No relation with the degree of necrosis achieved was found for the size of the nodules detected at imaging, the enhancement pattern, or the number of chemoembolization treatments. The degree of necrosis achieved depends on the time spent on the waiting list, on the number of nodules in the specimen, and on whether capsular infiltration is present. Copyright © 2014 SERAM. Published by Elsevier España, S.L.U. All rights reserved.

Impact of vineyard abandonment and natural recolonization on metal content and availability in Mediterranean soils.

PubMed

de Santiago-Martín, Ana; Vaquero-Perea, Cristina; Valverde-Asenjo, Inmaculada; Quintana Nieto, Jose R; González-Huecas, Concepción; Lafuente, Antonio L; Vázquez de la Cueva, Antonio

2016-05-01

Abandonment of vineyards after uprooting has dramatically increased in last decades in Mediterranean countries, often followed by vegetation expansion processes. Inadequate management strategies can have negative consequences on soil quality. We studied how the age and type of vegetation cover and several environmental characteristics (lithology, soil properties, vineyard slope and so on) after vineyard uprooting and abandonment contribute to the variation patterns in total, HAc (acetic acid-method, HAc) and EDTA-extractable (ethylenediaminetetraacetic acid-method) concentrations of Cd, Cu, Pb and Zn in soils. We sampled 141 points from vineyards and abandoned vineyard Mediterranean soils recolonized by natural vegetation in recent decades. The contribution of several environmental variables (e.g. age and type of vegetation cover, lithology, soil properties and vineyard slope) to the total and extractable concentrations of metals was evaluated by canonical ordination based on redundancy analysis, considering the interaction between both environmental and response variables. The ranges of total metal contents were: 0.01-0.15 (Cd), 2.6-34 (Cu), 6.6-30 (Pb), and 29-92mgkg(-1) (Zn). Cadmium (11-100%) had the highest relative extractability with both extractants, and Zn and Pb the lowest. The total and EDTA-extractable of Cd, Pb and Zn were positively related to the age of abandonment, to the presence of Agrostis castellana and Retama sphaerocarpa, and to the contents of Fe-oxides, clay and organic matter (OM). A different pattern was noted for Cu, positively related to vineyard soils. Soil properties successfully explained HAc-extractable Cd, Cu, Pb and Zn but the age and type of vegetation cover lost significance. Clay content was negatively related to HAc-extractable Cu and Pb; and OM was positively related to HAc-Cd and Zn. In conclusion, the time elapsed after vineyard uprooting, and subsequent land abandonment, affects the soil content and availability of metals, and this impact depended on the colonizing plant species and soil properties. Copyright © 2016 Elsevier B.V. All rights reserved.

Evaluation of Pseudo-Haptic Interactions with Soft Objects in Virtual Environments.

PubMed

Li, Min; Sareh, Sina; Xu, Guanghua; Ridzuan, Maisarah Binti; Luo, Shan; Xie, Jun; Wurdemann, Helge; Althoefer, Kaspar

2016-01-01

This paper proposes a pseudo-haptic feedback method conveying simulated soft surface stiffness information through a visual interface. The method exploits a combination of two feedback techniques, namely visual feedback of soft surface deformation and control of the indenter avatar speed, to convey stiffness information of a simulated surface of a soft object in virtual environments. The proposed method was effective in distinguishing different sizes of virtual hard nodules integrated into the simulated soft bodies. To further improve the interactive experience, the approach was extended creating a multi-point pseudo-haptic feedback system. A comparison with regards to (a) nodule detection sensitivity and (b) elapsed time as performance indicators in hard nodule detection experiments to a tablet computer incorporating vibration feedback was conducted. The multi-point pseudo-haptic interaction is shown to be more time-efficient than the single-point pseudo-haptic interaction. It is noted that multi-point pseudo-haptic feedback performs similarly well when compared to a vibration-based feedback method based on both performance measures elapsed time and nodule detection sensitivity. This proves that the proposed method can be used to convey detailed haptic information for virtual environmental tasks, even subtle ones, using either a computer mouse or a pressure sensitive device as an input device. This pseudo-haptic feedback method provides an opportunity for low-cost simulation of objects with soft surfaces and hard inclusions, as, for example, occurring in ever more realistic video games with increasing emphasis on interaction with the physical environment and minimally invasive surgery in the form of soft tissue organs with embedded cancer nodules. Hence, the method can be used in many low-budget applications where haptic sensation is required, such as surgeon training or video games, either using desktop computers or portable devices, showing reasonably high fidelity in conveying stiffness perception to the user.

Effectiveness of see-and-treat for approaching pre-invasive lesions of uterine cervix.

PubMed

Monteiro, Aparecida Cristina Sampaio; Russomano, Fábio; Reis, Aldo; Camargo, Maria José de; Fialho, Susana Aidé; Tristão, Maria Aparecida; Soares, Thiers

2009-10-01

To compare the effectiveness between the see-and-treat (S&T) approach and the conventional one (with prior biopsy) for squamous intraepithelial lesions of uterine cervix. A cross-sectional study was conducted with 900 nonpregnant women with cytology suggestive of high grade squamous intraepithelial lesions in the city of Rio de Janeiro, Southeastern Brazil, between 1998 and 2004. The S&T approach consists of a large loop excision of the transformation zone procedure and is recommended when cytology is suggestive of high grade squamous intraepithelial lesion, satisfactory colposcopy with abnormalities compatible with the suspected cytological results, and the lesion is limited to the ectocervix or extends up to one centimeter of the endocervical canal. A subgroup of 336 patients whose colposcopy was considered satisfactory was analyzed, and they were divided into two groups for comparison: patients treated without prior biopsy (n = 288) and patients treated after a biopsy showing high grade squamous intraepithelial lesions (n = 48). Patients who were not treated or only treated more than a year later after recruitment at the colposcopy unit were considered dropouts. Of patients recruited during the study period, 71 were not treated or were only treated for at least a year. The overall dropout rate was 7.9% (95% CI: 6.1;9.7). Mean time elapsed between patient recruitment and treatment was 17.5 days in the S&T group and 102.5 days in the prior biopsy group. Dropout rates were 1.4% (95% CI: 0.04;2.7) and 5.% (95% CI: 0;12.3), respectively (p=0.07). The proportion of overtreated cases (negative histology) in the S&T group was 2.0% (95% CI: 0.4;3.6). The difference in the mean time elapsed between patient recruitment and treatment indicates that S&T is a time-saving approach The proportion of negative cases from using the S&T approach can be regarded as low.

[Comparison of surgical patients with gastroesophageal reflux disease and Barrett's esophagus].

PubMed

Zsolt, Simonka; Paszt, Attila; Géczi, Tibor; Abrahám, Szabolcs; Tóth, Illés; Horváth, Zoltán; Pieler, József; Tajti, János; Varga, Akos; Tiszlavicz, László; Németh, István; Izbéki, Ferenc; Rosztóczy, András; Wittmann, Tibor; Lázár, György

2014-10-01

Barrett's esophagus (BE) is the only known precursor of adenocarcinoma occuring in the lower third of the esophagus. According to statistics, severity and elapsed time of gastroesophageal reflux disease (GERD) are major pathogenetic factors in the development of Barrett's esophagus. In a retrospective study between 2001 and 2008, we compared the preoperative results (signs and sympthoms, 24 hour pH manometry, esophageal manometry, Bilitec) and treatment efficacy of 176 GERD patients and 78 BE patients, who have undergone laparoscopic Nissen procedure for reflux disease. The two groups of patients had similar demographic features, and elapsed time of reflux sympthoms were also equal. Both groups were admitted for surgery after a median time of 1.5 years (19.87 vs. 19.20 months) of ineffective medical (proton pump inhibitors) treatment. Preoperative functional tests showed a more severe presence of acid reflux in the BE group (DeMeester score 18.9 versus 41.9, p < 0.001). On the other hand, mano-metry - despite confirming lower esophageal sphincter (LES) damage - did not show difference between the two groups (12.10 vs. 12.57 mmHg, p = 0.892). We did not experience any mortality cases with laparoscopic antireflux procedures, although in two cases we had to convert during the operation (1 due to extensive adhesions, and 1 due to injury to the spleen). 3 months after the procedure - according to Visick score - both groups experienced a significant decrease, or lapse in reflux complaints (group I: 73%, group II: 81% of patients), LES functions improved (17.58 vs.18.70 mmHg), and the frequency and exposition of acid reflux decreased (DeMeester score 7.73 vs. 12.72). The severity of abnormal acid reflux occuring parallel with the incompetent function of the damaged LES triggers not only inflammation in the gastroesophageal junction (GEJ), but also metaplastic process, and the development of Barrett's esophagus. Laparoscopic Nissen procedure for reflux disease can further improve outcome among patients with GERD not responding to conservative therapy.

Energy consumption of ProTaper Next X1 after glide path with PathFiles and ProGlider.

PubMed

Berutti, Elio; Alovisi, Mario; Pastorelli, Michele Angelo; Chiandussi, Giorgio; Scotti, Nicola; Pasqualini, Damiano

2014-12-01

Instrument failure caused by excessive torsional stress can be controlled by creating a manual or mechanical glide path. The ProGlider single-file system (Dentsply Maillefer, Ballaigues, Switzerland) was recently introduced to perform a mechanical glide path. This study was designed to compare the effect of a glide path performed with PathFiles (Dentsply Maillefer) and ProGlider on torque, time, and pecking motion required for ProTaper Next X1 (Dentsply Maillefer) to reach the full working length in simulated root canals. Forty Endo Training Blocks (Dentsply Maillefer) were used. Twenty were prepared with a mechanical glide path using PathFiles 1 and 2 (the PathFile group), and 20 were prepared with a mechanical glide path using a ProGlider single file (the ProGlider group). All samples were shaped with ProTaper Next X1 driven by an endodontic motor connected to a digital wattmeter. The required torque for root canal instrumentation was analyzed by evaluating the electrical power consumption of the endodontic engine. Electric power consumption (mW/h), elapsed time (seconds), and number of pecking motions required to reach the full working length with ProTaper Next X1 were calculated. Differences among groups were analyzed with the parametric Student t test for independent data (P < .05). Elapsed time and electric power consumption were significantly different between groups (P = .0001 for both). ProGlider appears to perform more efficiently than PathFiles in decreasing electric power consumption of ProTaper Next X1 to reach the full working length. This study confirmed the ability of ProGlider to reduce stress in ProTaper Next X1 during shaping through a glide path and preliminary middle and coronal preflaring. Copyright © 2014 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

The Relative Contributions of the Homeostatic and Circadian Processes to Sleep Regulation under Conditions of Severe Sleep Restriction

PubMed Central

Paech, Gemma M.; Ferguson, Sally A.; Sargent, Charli; Kennaway, David J.; Roach, Gregory D.

2012-01-01

Study Objectives: To investigate the relative contributions of the homeostatic and circadian processes on sleep regulation under conditions of severe sleep restriction. Design: The 13-day laboratory based study consisted of 3 × 24-h baseline days (8 h sleep opportunity, 16 h wake) followed by 7 × 28-h forced desynchrony days (4.7 h sleep opportunity, 23.3 h wake). Setting: The study was conducted in a time isolation unit at the Centre for Sleep Research, University of South Australia. Participants: Fourteen healthy, nonsmoking males, aged 21.8 ± 3.8 (mean ± SD) years participated in the study. Interventions: N/A Measurements: Sleep was measured using standard polysomnography. Core body temperature (CBT) was recorded continuously using a rectal thermistor. Each epoch of sleep was assigned a circadian phase based on the CBT data (6 × 60-degree bins) and an elapsed time into sleep episode (2 × 140-min intervals). Results: The percentage of SWS decreased with elapsed time into the sleep episode. However, no change in the percentage of REM sleep was observed with sleep progression. Whilst there was a circadian modulation of REM sleep, the amplitude of the circadian variation was smaller than expected. Sleep efficiency remained high throughout the sleep episode and across all circadian phases. Conclusions: Previous forced desynchrony studies have demonstrated a strong circadian influence on sleep, in the absence of sleep restriction. The current study suggests that in the presence of high homeostatic pressure, the circadian modulation of sleep, in particular sleep efficiency and to a lesser extent, REM sleep, are reduced. Citation: Paech GM; Ferguson SA; Sargent C; Kennaway DJ; Roach GD. The relative contributions of the homeostatic and circadian processes to sleep regulation under conditions of severe sleep restriction. SLEEP 2012;35(7):941-948. PMID:22754040