DOE Office of Scientific and Technical Information (OSTI.GOV)

Zissa, D.E.; Barnes, V.E.; Carmony, D.D.

We have measured the total and subchannel cross sections for the reaction p-barp..-->..p-barp..pi../sup +/..pi../sup -/ at 49 GeV/c. This reaction is dominated by two production mechanisms, diffraction and meson exchange. In addition, we have measured the total cross section for p-barp..-->..p-barp2..pi../sup +/2..pi../sup -/ and compared it to values at other momenta and with the corresponding pp interaction. Within the present statistics, no significant amount of exclusive annihilation is found into two, four, and six charged pions.

Femtosecond UV-laser pulses to unveil protein-protein interactions in living cells.

PubMed

Itri, Francesco; Monti, Daria M; Della Ventura, Bartolomeo; Vinciguerra, Roberto; Chino, Marco; Gesuele, Felice; Lombardi, Angelina; Velotta, Raffaele; Altucci, Carlo; Birolo, Leila; Piccoli, Renata; Arciello, Angela

2016-02-01

A hallmark to decipher bioprocesses is to characterize protein-protein interactions in living cells. To do this, the development of innovative methodologies, which do not alter proteins and their natural environment, is particularly needed. Here, we report a method (LUCK, Laser UV Cross-linKing) to in vivo cross-link proteins by UV-laser irradiation of living cells. Upon irradiation of HeLa cells under controlled conditions, cross-linked products of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) were detected, whose yield was found to be a linear function of the total irradiation energy. We demonstrated that stable dimers of GAPDH were formed through intersubunit cross-linking, as also observed when the pure protein was irradiated by UV-laser in vitro. We proposed a defined patch of aromatic residues located at the enzyme subunit interface as the cross-linking sites involved in dimer formation. Hence, by this technique, UV-laser is able to photofix protein surfaces that come in direct contact. Due to the ultra-short time scale of UV-laser-induced cross-linking, this technique could be extended to weld even transient protein interactions in their native context.

A New Scaling Law of Resonance in Total Scattering Cross Section in Gases

NASA Astrophysics Data System (ADS)

Raju, Gorur Govinda

2009-10-01

Electrical discharges in gases continue to be an active area of research because of industrial applications such as power systems, environmental clean up, laser technology, semiconductor fabrication etc. A fundamental knowledge of electron-gas neutral interaction is indispensable and, the total scattering cross section is one of the quantities that have been measured extensively. The energy dependence of the total cross sections shows peaks or resonance processes that are operative in the collision process. These peaks and the energies at which they occur are shown to satisfy a broad relationship involving the polarizability and the dipole moment of the target particle. Data on 62 target particles belonging to the following species are analyzed. (Eq 1) Rare gas atoms (Eq 2) Di-atomic molecules with combinations of polar, non-polar, attaching, and non-attaching properties Poly-atomic molecules with combinations of polar, non-polar, attaching, and non-attaching properties. Methods of improving the newly identified scaling law and possible application have been identified. 1 INTRODUCTION: Data on electron-neutral interactions are one of the most fundamental in the study of gaseous electronics and an immense literature, both experimental and theoretical, has become available since about the year 1920. [1-5]. In view of the central role which these data play in all facets of gas discharges and plasma science, it is felt that a critical review of available data is timely, mainly for the community of high voltage engineers and industries connected with plasma science in general. The electron-neutral interaction, often referred to as scattering in the scientific literature, is quantified by using the quantity called the total scattering cross section (QT, m^2). In the literature on cross section, total cross section and total scattering cross section are terms used synonymously and we follow the same practice. A definition may be found in reference [1]. This paper concerns scaling of total cross section of gases at resonance energy and the electron energy at which resonance occurs. The meaning of resonance is briefly explained in the following section. Here, we use the term scaling to relate the two quantities mentioned, namely, the resonance energy and the total cross section at that energy. Consistent with the definition of scaling, if the law proposed holds, one of the two quantities mentioned above may be calculated if the other is known. Such a method is very useful in gas discharge modeling and calculation of breakdown voltages, as more fully explained in the later section of the paper. 2 DESCRIPTION OF RESONANCE: A brief description of resonance phenomena in several types of target particles, viz., atomic, poly atomic, polar, non-polar phenomena are presented. 3 PREVIOUS SCALING LAWS: A common representation of a given characteristic with as few adjustable parameters as possible is generally known as the scaling law. The Paschen curve for breakdown voltage is such a familiar scaling law. With reference to cross sections several attempts have been made to obtain a scaling law, with varying degree of success. If the cross section-energy curve is qualitatively similar without having sharp peaks and oscillations, moderately successful scaling laws may be devised. For example, the ionization cross section- energy curves for most gases follow a general pattern. Several published scaling laws are discussed. 4 A NEW SCALING LAW AND DISCUSSION: In this work the author has compiled the resonance details for more than 60 gasest hat include the range from simple atoms to complex molecules that are polyatomic, dipolar, electron-attaching and isomers. The target particles exhibit a number of distinct features, as far as their total cross section variation with electron energy is concerned as already explained.

Electromagnetic Dissociation and Spacecraft Electronics Damage

NASA Technical Reports Server (NTRS)

Norbury, John W.

2016-01-01

When protons or heavy ions from galactic cosmic rays (GCR) or solar particle events (SPE) interact with target nuclei in spacecraft, there can be two different types of interactions. The more familiar strong nuclear interaction often dominates and is responsible for nuclear fragmentation in either the GCR or SPE projectile nucleus or the spacecraft target nucleus. (Of course, the proton does not break up, except possibly to produce pions or other hadrons.) The less familiar, second type of interaction is due to the very strong electromagnetic fields that exist when two charged nuclei pass very close to each other. This process is called electromagnetic dissociation (EMD) and primarily results in the emission of neutrons, protons and light ions (isotopes of hydrogen and helium). The cross section for particle production is approximately defined as the number of particles produced in nucleus-nucleus collisions or other types of reactions. (There are various kinematic and other factors which multiply the particle number to arrive at the cross section.) Strong, nuclear interactions usually dominate the nuclear reactions of most interest that occur between GCR and target nuclei. However, for heavy nuclei (near Fe and beyond) at high energy the EMD cross section can be much larger than the strong nuclear interaction cross section. This paper poses a question: Are there projectile or target nuclei combinations in the interaction of GCR or SPE where the EMD reaction cross section plays a dominant role? If the answer is affirmative, then EMD mechanisms should be an integral part of codes that are used to predict damage to spacecraft electronics. The question can become more fine-tuned and one can ask about total reaction cross sections as compared to double differential cross sections. These issues will be addressed in the present paper.

Low- ν Flux and Total Charged-current Cross Sections in MINERvA

NASA Astrophysics Data System (ADS)

Ren, Lu

2014-03-01

The MINER νA experiment measures neutrino and antineutrino interaction cross sections on carbon and other nuclei. Cross section measurements require accurate knowledge of the incident neutrino flux. The ``low- ν'' flux technique uses a standard-candle cross section for events with low energy transfer to to the hadronic system to determine the incident flux. MINER νA will use low- ν fluxes for neutrinos and antineutrinos to tune production models used in beam simulations and to extract total cross sections as a function of energy. We present the low- ν flux technique adapted for the MINER νA data samples and preliminary results for the extracted low- ν fluxes in MINER νA. MINER νA will extend the range of antineutino charged-current cross section measurements to lower energies which are of interest to future accelerator oscillation experiments.

Connection of the virtual γ*p cross section of ep deep inelastic scattering to real γp scattering, and the implications for νN and ep total cross sections

NASA Astrophysics Data System (ADS)

Block, Martin M.; Durand, Loyal; Ha, Phuoc

2014-05-01

We show that it is possible to fit all of the HERA deep inelastic scattering data on F2γp at small values of Bjorken x, including the data at very low Q2, using a new model for F2γp which both includes an asymptotic (high-energy) part that satisfies a saturated Froissart bound behavior, with a vector-dominance-like mass factor in the parametrization, and extends smoothly to Q2=0. We require that the corresponding part of the virtual γ*p cross section match the known asymptotic part of the real γp cross section at Q2=0, a cross section which is determined by strong interactions and asymptotically satisfies a saturated Froissart bound of the form α+βlns+γln2s. Using this model for the asymptotic part of F2γp plus a known valence contribution, we fit the asymptotic high-energy part of the HERA data with x ≤0.1 and W ≥25 GeV; the fit is excellent. We find that the mass parameter in the fit lies in the region of the light vector mesons, somewhat above the ρ-meson mass, and is compatible with vector dominance. We use this fit to obtain accurate results for the high-energy ep and isoscalar νN total cross sections. Both cross sections obey an analytic expression of the type a+blnE+cln2E+dln3E at large energies E of the incident particle, reflecting the fact that the underlying strong interaction parts of the γ*p, Z*N and W*N cross sections satisfy the saturated Froissart bound. Since approximately 50% of the νN center-of-mass (cms) energy is found in W—the cms energy of the strongly interacting intermediate vector boson-nucleon system—a study of ultra-high-energy neutrino-nucleon cross sections would allow us, for the first time, to explore strong interactions at incredibly high energies.

Low-lying electric-dipole strengths of Ca, Ni, and Sn isotopes imprinted on total reaction cross sections

NASA Astrophysics Data System (ADS)

Horiuchi, W.; Hatakeyama, S.; Ebata, S.; Suzuki, Y.

2017-08-01

Low-lying electric-dipole (E 1 ) strength of a neutron-rich nucleus contains information on neutron-skin thickness, deformation, and shell evolution. We discuss the possibility of making use of total reaction cross sections on 40Ca, 120Sn, and 208Pb targets to probe the E 1 strength of neutron-rich Ca, Ni, and Sn isotopes. They exhibit large enhancement of the E 1 strength at neutron number N >28 , 50, and 82, respectively, due to a change of the single-particle orbits near the Fermi surface participating in the transitions. The density distributions and the electric-multipole strength functions of those isotopes are calculated by the Hartree-Fock+BCS and the canonical-basis-time-dependent-Hartree-Fock-Bogoliubov methods, respectively, using three kinds of Skyrme-type effective interaction. The nuclear and Coulomb breakup processes are respectively described with the Glauber model and the equivalent photon method in which the effect of finite-charge distribution is taken into account. The three Skyrme interactions give different results for the total reaction cross sections because of different Coulomb breakup contributions. The contribution of the low-lying E 1 strength is amplified when the low-incident energy is chosen. With an appropriate choice of the incident energy and target nucleus, the total reaction cross section can be complementary to the Coulomb excitation for analyzing the low-lying E 1 strength of unstable nuclei.

Effect of the magnetic dipole interaction on a spin-1 system

NASA Astrophysics Data System (ADS)

Hu, Fangqi; Jia, Wei; Zhao, Qing

2018-05-01

We consider a hybrid system composed of a spin-1 triplet coupled to a nuclear spin. We study the effect of the axisymmetric and the quadrupole term of the magnetic dipole interaction between the two electrons forming the triplet on the energy spectrum in a static magnetic field. The energy spectrum obtained by directly diagonalizing the Hamiltonian of the system shows that these two terms not only remove the special crossings that appear in the absence of the magnetic dipole interaction, but also produce new (avoided) crossings by lifting the relevant levels. Specially, the gaps between the avoided crossing levels increase with the strength of the quadrupole term. In order to accurately illustrate these effects, we present the results for the discriminant and von Neumann entropy of one electron interacting with the rest of the whole system. Finally, by numerically solving the time-dependent Schrödinger equations of the system, we discover that the polarization oscillation of electron and nuclear spin is in-phase and the total average longitudinal spin is not conserved at location of avoided crossing, but the two results are opposite beyond that.

Measurement of the inclusive νμ charged current cross section on carbon in the near detector of the T2K experiment

NASA Astrophysics Data System (ADS)

Abe, K.; Abgrall, N.; Aihara, H.; Akiri, T.; Albert, J. B.; Andreopoulos, C.; Aoki, S.; Ariga, A.; Ariga, T.; Assylbekov, S.; Autiero, D.; Barbi, M.; Barker, G. J.; Barr, G.; Bass, M.; Batkiewicz, M.; Bay, F.; Bentham, S. W.; Berardi, V.; Berger, B. E.; Berkman, S.; Bertram, I.; Beznosko, D.; Bhadra, S.; Blaszczyk, F. d. M.; Blondel, A.; Bojechko, C.; Boyd, S.; Brailsford, D.; Bravar, A.; Bronner, C.; Brook-Roberge, D. G.; Buchanan, N.; Calland, R. G.; Caravaca Rodríguez, J.; Cartwright, S. L.; Castillo, R.; Catanesi, M. G.; Cervera, A.; Cherdack, D.; Christodoulou, G.; Clifton, A.; Coleman, J.; Coleman, S. J.; Collazuol, G.; Connolly, K.; Cremonesi, L.; Curioni, A.; Dabrowska, A.; Danko, I.; Das, R.; Davis, S.; Day, M.; de André, J. P. A. M.; de Perio, P.; De Rosa, G.; Dealtry, T.; Dennis, S. R.; Densham, C.; Di Lodovico, F.; Di Luise, S.; Dobson, J.; Drapier, O.; Duboyski, T.; Dufour, F.; Dumarchez, J.; Dytman, S.; Dziewiecki, M.; Dziomba, M.; Emery, S.; Ereditato, A.; Escudero, L.; Finch, A. J.; Frank, E.; Friend, M.; Fujii, Y.; Fukuda, Y.; Furmanski, A. P.; Galymov, V.; Gaudin, A.; Giffin, S.; Giganti, C.; Gilje, K.; Golan, T.; Gomez-Cadenas, J. J.; Gonin, M.; Grant, N.; Gudin, D.; Guzowski, P.; Hadley, D. R.; Haesler, A.; Haigh, M. D.; Hamilton, P.; Hansen, D.; Hara, T.; Hartz, M.; Hasegawa, T.; Hastings, N. C.; Hayato, Y.; Hearty, C.; Helmer, R. L.; Hierholzer, M.; Hignight, J.; Hillairet, A.; Himmel, A.; Hiraki, T.; Holeczek, J.; Horikawa, S.; Huang, K.; Ichikawa, A. K.; Ieki, K.; Ieva, M.; Ikeda, M.; Imber, J.; Insler, J.; Irvine, T. J.; Ishida, T.; Ishii, T.; Ives, S. J.; Iyogi, K.; Izmaylov, A.; Jacob, A.; Jamieson, B.; Johnson, R. A.; Jo, J. H.; Jonsson, P.; Joo, K. K.; Jung, C. K.; Kaboth, A.; Kaji, H.; Kajita, T.; Kakuno, H.; Kameda, J.; Kanazawa, Y.; Karlen, D.; Karpikov, I.; Kearns, E.; Khabibullin, M.; Khanam, F.; Khotjantsev, A.; Kielczewska, D.; Kikawa, T.; Kilinski, A.; Kim, J. Y.; Kim, J.; Kim, S. B.; Kirby, B.; Kisiel, J.; Kitching, P.; Kobayashi, T.; Kogan, G.; Kolaceke, A.; Konaka, A.; Kormos, L. L.; Korzenev, A.; Koseki, K.; Koshio, Y.; Kowalik, K.; Kreslo, I.; Kropp, W.; Kubo, H.; Kudenko, Y.; Kumaratunga, S.; Kurjata, R.; Kutter, T.; Lagoda, J.; Laihem, K.; Laing, A.; Laveder, M.; Lawe, M.; Lee, K. P.; Licciardi, C.; Lim, I. T.; Lindner, T.; Lister, C.; Litchfield, R. P.; Longhin, A.; Lopez, G. D.; Ludovici, L.; Macaire, M.; Magaletti, L.; Mahn, K.; Malek, M.; Manly, S.; Marchionni, A.; Marino, A. D.; Marteau, J.; Martin, J. F.; Maruyama, T.; Marzec, J.; Masliah, P.; Mathie, E. L.; Matveev, V.; Mavrokoridis, K.; Mazzucato, E.; McCauley, N.; McFarland, K. S.; McGrew, C.; McLachlan, T.; Messina, M.; Metelko, C.; Mezzetto, M.; Mijakowski, P.; Miller, C. A.; Minamino, A.; Mineev, O.; Mine, S.; Missert, A.; Miura, M.; Monfregola, L.; Moriyama, S.; Mueller, Th. A.; Murakami, A.; Murdoch, M.; Murphy, S.; Myslik, J.; Nagasaki, T.; Nakadaira, T.; Nakahata, M.; Nakai, T.; Nakajima, K.; Nakamura, K.; Nakayama, S.; Nakaya, T.; Nakayoshi, K.; Naples, D.; Nicholls, T. C.; Nielsen, C.; Nishikawa, K.; Nishimura, Y.; O'Keeffe, H. M.; Obayashi, Y.; Ohta, R.; Okumura, K.; Okusawa, T.; Oryszczak, W.; Oser, S. M.; Otani, M.; Owen, R. A.; Oyama, Y.; Pac, M. Y.; Palladino, V.; Paolone, V.; Payne, D.; Pearce, G. F.; Perevozchikov, O.; Perkin, J. D.; Pinzon Guerra, E. S.; Plonski, P.; Poplawska, E.; Popov, B.; Posiadala, M.; Poutissou, J.-M.; Poutissou, R.; Przewlocki, P.; Quilain, B.; Radicioni, E.; Ratoff, P. N.; Ravonel, M.; Rayner, M. A. M.; Reeves, M.; Reinherz-Aronis, E.; Retiere, F.; Robert, A.; Rodrigues, P. A.; Rondio, E.; Roth, S.; Rubbia, A.; Ruterbories, D.; Sacco, R.; Sakashita, K.; Sánchez, F.; Scantamburlo, E.; Scholberg, K.; Schwehr, J.; Scott, M.; Scully, D. I.; Seiya, Y.; Sekiguchi, T.; Sekiya, H.; Sgalaberna, D.; Shibata, M.; Shiozawa, M.; Short, S.; Shustrov, Y.; Sinclair, P.; Smith, B.; Smith, R. J.; Smy, M.; Sobczyk, J. T.; Sobel, H.; Sorel, M.; Southwell, L.; Stamoulis, P.; Steinmann, J.; Still, B.; Suzuki, A.; Suzuki, K.; Suzuki, S. Y.; Suzuki, Y.; Szeglowski, T.; Szeptycka, M.; Tacik, R.; Tada, M.; Takahashi, S.; Takeda, A.; Takeuchi, Y.; Tanaka, H. A.; Tanaka, M. M.; Tanaka, M.; Taylor, I. J.; Terhorst, D.; Terri, R.; Thompson, L. F.; Thorley, A.; Tobayama, S.; Toki, W.; Tomura, T.; Totsuka, Y.; Touramanis, C.; Tsukamoto, T.; Tzanov, M.; Uchida, Y.; Ueno, K.; Vacheret, A.; Vagins, M.; Vasseur, G.; Wachala, T.; Waldron, A. V.; Walter, C. W.; Wang, J.; Wark, D.; Wascko, M. O.; Weber, A.; Wendell, R.; Wilkes, R. J.; Wilking, M. J.; Wilkinson, C.; Williamson, Z.; Wilson, J. R.; Wilson, R. J.; Wongjirad, T.; Yamada, Y.; Yamamoto, K.; Yanagisawa, C.; Yen, S.; Yershov, N.; Yokoyama, M.; Yuan, T.; Zalewska, A.; Zambelli, L.; Zaremba, K.; Ziembicki, M.; Zimmerman, E. D.; Zito, M.; Żmuda, J.

2013-05-01

T2K has performed the first measurement of νμ inclusive charged current interactions on carbon at neutrino energies of ˜1GeV where the measurement is reported as a flux-averaged double differential cross section in muon momentum and angle. The flux is predicted by the beam Monte Carlo and external data, including the results from the NA61/SHINE experiment. The data used for this measurement were taken in 2010 and 2011, with a total of 10.8×1019 protons-on-target. The analysis is performed on 4485 inclusive charged current interaction candidates selected in the most upstream fine-grained scintillator detector of the near detector. The flux-averaged total cross section is ⟨σCC⟩ϕ=(6.91±0.13(stat)±0.84(syst))×10-39(cm2)/(nucleon) for a mean neutrino energy of 0.85 GeV.

Problem of the Optical Model for Deuterons; ZAGADNIENIA MODELU OPTYCZNEGO DLA DEUTERONOW

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grotowski, K.

1963-01-01

Problems concerning parameters of the optical potential for deuterons are presented. Total cross-sections for the interaction of deuterons with nuclei were determined by the evaluation of the cross-sections for the emission of charged particles and neutrons. The angular distributions for the elastic scattering of deuterons were also measured, 47 references. (auth)

Family Interaction and Cognitive Style: Situation and Cross-Sex Effects.

ERIC Educational Resources Information Center

Dreyer, Albert S.

This study was designed to examine the family interaction differentiating the families of field dependent and field independent children. A total of 300 white, middle class, kindergarten children were tested with the Portable Rod and Frame Test and the Children.s Embedded Figures Test and were classified as field dependent or field independent…

Study of electron impact inelastic scattering of chlorine molecule (Cl2)

NASA Astrophysics Data System (ADS)

Yadav, Hitesh; Vinodkumar, Minaxi; Limbachiya, Chetan; Vinodkumar, P. C.

2018-02-01

A theoretical study is carried out for electron interactions with the chlorine molecule (Cl2) for incident energies ranging from 0.01 to 5000 eV. This wide range of energy has allowed us to investigate a variety of processes and report data on symmetric excitation energies, dissociative electron attachment (DEA), total excitation cross sections, and ionization cross section (Q ion) along with total inelastic cross sections (Q inel). The present study is important since Cl2 is a prominent gas for plasma etching and its anionic atoms are important in the etching of semiconductor wafers. In order to compute the total inelastic cross sections, we have employed the ab initio R-matrix method (0.01 to 15 eV) together with the spherical complex optical potential method (∼15 to 5000 eV). The R-matrix calculations are performed using a close coupling method, and we have used DEA estimator via Quantemol-N to calculate the DEA fragmentation and cross sections. The present study finds overall good agreement with the available experimental data. Total excitation and inelastic cross sections of e-{{{Cl}}}2 scattering for a wide energy range (0.01 to 5 keV) are reported for the first time, to the best of our knowledge.

Image charge effects on electron capture by dust grains in dusty plasmas.

PubMed

Jung, Y D; Tawara, H

2001-07-01

Electron-capture processes by negatively charged dust grains from hydrogenic ions in dusty plasmas are investigated in accordance with the classical Bohr-Lindhard model. The attractive interaction between the electron in a hydrogenic ion and its own image charge inside the dust grain is included to obtain the total interaction energy between the electron and the dust grain. The electron-capture radius is determined by the total interaction energy and the kinetic energy of the released electron in the frame of the projectile dust grain. The classical straight-line trajectory approximation is applied to the motion of the ion in order to visualize the electron-capture cross section as a function of the impact parameter, kinetic energy of the projectile ion, and dust charge. It is found that the image charge inside the dust grain plays a significant role in the electron-capture process near the surface of the dust grain. The electron-capture cross section is found to be quite sensitive to the collision energy and dust charge.

Secondary neutron-production cross sections from heavy-ion interactions in composite targets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heilbronn, L.; Iwata, Y.; Murakami, T.

Secondary neutron-production cross sections have been measured from interactions of 290 MeV/nucleon C and 600 MeV/nucleon Ne in a target composed of simulated Martian regolith and polyethylene, and from 400 MeV/nucleon Ne interactions in wall material from the International Space Station. The data were measured between 5 deg. and 80 deg. in the laboratory. We report the double-differential cross sections, angular distributions, and total neutron-production cross sections from all three systems. The spectra from all three systems exhibit behavior previously reported in other heavy-ion neutron-production experiments, namely, a peak at forward angles near the energy corresponding to the beam velocity,more » with the remaining spectra generated by pre-equilibrium and equilibrium processes. The double-differential cross sections are fitted with a moving-source parametrization. Also reported are the data without corrections for neutron flux attenuation in the target and other intervening materials and for neutron production in nontarget materials near the target position. These uncorrected spectra are compared with SHIELD-HIT and PHITS transport model calculations. The transport model calculations reproduce the spectral shapes well but, on average, underestimate the magnitudes of the cross sections.« less

On the Conservation of Cross Helicity and Wave Action in Solar-wind Models with Non-WKB Alfvén Wave Reflection

NASA Astrophysics Data System (ADS)

Chandran, Benjamin D. G.; Perez, Jean C.; Verscharen, Daniel; Klein, Kristopher G.; Mallet, Alfred

2015-09-01

The interaction between Alfvén-wave turbulence and the background solar wind affects the cross helicity (\\int {d}3x {\\boldsymbol{v}}\\cdot {\\boldsymbol{B}}) in two ways. Non-WKB reflection converts outward-propagating Alfvén waves into inward-propagating Alfvén waves and vice versa, and the turbulence transfers momentum to the background flow. When both effects are accounted for, the total cross helicity is conserved. In the special case that the background density and flow speed are independent of time, the equations of cross-helicity conservation and total-energy conservation can be combined to recover a well-known equation derived by Heinemann and Olbert that has been interpreted as a non-WKB generalization of wave-action conservation. This latter equation (in contrast to cross-helicity and energy conservation) does not hold when the background varies in time.

The Antiproton-Nucleon Annihilation Process (Antiproton Collaboration Experiment)

DOE R&D Accomplishments Database

Barkas, W. H.; Birge, R. W.; Chupp, W. W.; Ekspong, A. G.; Goldhaber, G.; Goldhaber, S.; Heckman, H. H.; Perkins, D. H.; Sandweiss, J.; Segre, E.; Smith, F. M.; Stork, D. H.; Rossum, L. Van; Amaldi, E.; Baroni, G.; Castagnoli, C.; Franzinetti, C.; Manfredini, A.

1956-09-10

In the exposure to a 700-MeV/c negative particle beam, 35 antiproton stars have been found. Of these antiprotons, 21 annihilate in flight and three give large-angle scatters ({Theta} > 15 , T{sub P-} > 50 Mev), while 14 annihilate at rest. From the interactions in flight we obtain the total cross section for antiproton interaction.

A study of the EMC effect using neutrino and antineutrino interactions in neon and deuterium

NASA Astrophysics Data System (ADS)

Guy, J.; Saitta, B.; van Apeldoorn, G.; Allport, P.; Angelini, C.; Armenise, N.; Baldini, A.; Berggren, M.; Bertrand, D.; Bobisut, F.; Brisson, V.; Bullock, F.; Calicchio, M.; Capiluppi, P.; Cirio, R.; Clayton, E. F.; Coghen, T.; Cooper-Sarkar, A. M.; Erriquez, O.; Faccini-Turluer, M. L.; Fitch, P.; Frodesen, A. G.; Gerbier, G.; Giacomelli, G.; Hulth, P. O.; Jones, G. T.; Jongejans, B.; Kasper, P.; Klein, H.; Mandrioli, G.; Marage, P.; Marzari-Chiesa, A.; Middleton, R. P.; Miller, D. B.; Morrison, D. R. O.; Mobayyen, M. M.; O'Neale, S. W.; Neveu, M.; Parker, M. A.; Petiau, P.; Romero, A.; Rossi, A. M.; Sacton, J.; Sansum, A.; Sconza, A.; Simopoulou, E.; Schmitz, N.; Tenner, A.; Vallee, C.; van Eijndhoven, N.; Varvell, K.; Vayaki, A.; Venus, W.; Vignaud, D.; Wachsmuth, H.; Wittek, W.

1987-09-01

Nearly 40000 neutrino and antineutrino interactions in BEBC are compared to measure the differences between neon and deuterium in the quark and antiquark distributions and in the nucleon structure functions. The ratio of Ne to D cross sections indicates some decrease between x˜0.2 and x˜0.6. The y distributions show there is no significant increase in the neon sea, but prefer a small decrease. Taken altogether, the x and y distributions and the measured total cross-sections indicate some change in the shape of the valence distributions. No significant dependence on A is observed for either the shape of the sea or the ratio of longitudinal to transverse cross-sections.

The interaction of low-energy electrons with fructose molecules

NASA Astrophysics Data System (ADS)

Chernyshova, I. V.; Kontrosh, E. E.; Markush, P. P.; Shpenik, O. B.

2017-11-01

Using a hypocycloidal electronic spectrometer, the interactions of low energy electrons (0-8.50 eV) with fructose molecules, namely, electron scattering and dissociative attachment, are studied. The results of these studies showed that the fragmentation of fructose molecules occurs effectively even at an electron energy close to zero. In the total electron-scattering cross section by molecules, resonance features (at energies 3.10 and 5.00 eV) were first observed near the formation thresholds of light ion fragments OH- and H-. The correlation of the features observed in the cross sections of electron scattering and dissociative attachment is analyzed.

Differential Cross Sections for Proton-Proton Elastic Scattering

NASA Technical Reports Server (NTRS)

Norman, Ryan B.; Dick, Frank; Norbury, John W.; Blattnig, Steve R.

2009-01-01

Proton-proton elastic scattering is investigated within the framework of the one pion exchange model in an attempt to model nucleon-nucleon interactions spanning the large range of energies important to cosmic ray shielding. A quantum field theoretic calculation is used to compute both differential and total cross sections. A scalar theory is then presented and compared to the one pion exchange model. The theoretical cross sections are compared to proton-proton scattering data to determine the validity of the models.

First Measurement of one Pion Production in Charged Current Neutrino and Antineutrino events on Argon

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scanavini, Scanavini,Giacomo

This thesis presents a work done in the context of the Fermilab Neutrino Intensity Frontier. In this analysis, the cross section of single charged pion production in charged-current neutrino and antineutrino interactions with the argon nucleus target are measured. These measurements are performed using the Argon Neutrino Test (ArgoNeuT) detector exposed to the Fermilab Neutrino From The Main Injector (NuMI) beam operating in the low energy antineutrino mode. The signal is a charged-current μ interaction in the detector, with exactly one charged pion exiting the target nucleus, with momentum above 100 MeV/c. There shouldn’t be any 0 or kaons inmore » the final state. There is no restriction on other mesons or nucleons. Total and differential cross section measurements are presented. The results are reported in terms of outgoing muon angle and momentum, outgoing pion angle and angle between outgoing pion and muon. The total cross sections, averaged over the flux, are found to be 8.2 ± 0.9 (stat) +0.9 -1.1 (syst) × 10-38 cm2 per argon nuclei and 2.5 ± 0.4 (stat) ± 0.5 (syst) × 10-37 cm2 per argon nuclei for antineutrino and neutrino respectively at a mean neutrino energy of 3.6 GeV (antineutrinos) and 9.6 GeV (neutrinos). This is the first time the single pion production in charged-current interactions cross section is measured on argon nuclei.« less

Improvement of one-nucleon removal and total reaction cross sections in the Liège intranuclear-cascade model using Hartree-Fock-Bogoliubov calculations

NASA Astrophysics Data System (ADS)

Rodríguez-Sánchez, Jose Luis; David, Jean-Christophe; Mancusi, Davide; Boudard, Alain; Cugnon, Joseph; Leray, Sylvie

2017-11-01

The prediction of one-nucleon-removal cross sections by the Liège intranuclear-cascade model has been improved using a refined description of the matter and energy densities in the nuclear surface. Hartree-Fock-Bogoliubov calculations with the Skyrme interaction are used to obtain a more realistic description of the radial-density distributions of protons and neutrons, as well as the excitation-energy uncorrelation at the nuclear surface due to quantum effects and short-range correlations. The results are compared with experimental data covering a large range of nuclei, from carbon to uranium, and projectile kinetic energies. We find that the new approach is in good agreement with experimental data of one-nucleon-removal cross sections covering a broad range in nuclei and energies. The new ingredients also improve the description of total reaction cross sections induced by protons at low energies, the production cross sections of heaviest residues close to the projectile, and the triple-differential cross sections for one-proton removal. However, other observables such as quadruple-differential cross sections of coincident protons do not present any sizable sensitivity to the new approach. Finally, the model is also tested for light-ion-induced reactions. It is shown that the new parameters can give a reasonable description of the nucleus-nucleus total reaction cross sections at high energies.

Measurement of total and differential cross sections of neutrino and antineutrino coherent π± production on carbon

NASA Astrophysics Data System (ADS)

Mislivec, A.; Higuera, A.; Aliaga, L.; Bellantoni, L.; Bercellie, A.; Betancourt, M.; Bodek, A.; Bravar, A.; Budd, H.; Caceres v., G. F. R.; Cai, T.; Martinez Caicedo, D. A.; Carneiro, M. F.; Chavarria, E.; da Motta, H.; Dytman, S. A.; Díaz, G. A.; Felix, J.; Fields, L.; Fine, R.; Gago, A. M.; Galindo, R.; Gallagher, H.; Ghosh, A.; Gran, R.; Harris, D. A.; Hurtado, K.; Jena, D.; Kleykamp, J.; Kordosky, M.; Le, T.; Maher, E.; Manly, S.; Mann, W. A.; Marshall, C. M.; McFarland, K. S.; Messerly, B.; Miller, J.; Morfín, J. G.; Mousseau, J.; Naples, D.; Nelson, J. K.; Nguyen, C.; Norrick, A.; Nuruzzaman, Paolone, V.; Perdue, G. N.; Ramírez, M. A.; Ransome, R. D.; Ray, H.; Ren, L.; Rimal, D.; Rodrigues, P. A.; Ruterbories, D.; Schellman, H.; Solano Salinas, C. J.; Sultana, M.; Sánchez Falero, S.; Tagg, N.; Valencia, E.; Wospakrik, M.; Yaeggy, B.; Zavala, G.; MinerνA Collaboration

2018-02-01

Neutrino induced coherent charged pion production on nuclei, ν¯ μA →μ±π∓A , is a rare inelastic interaction in which the four-momentum squared transferred to the nucleus is nearly zero, leaving it intact. We identify such events in the scintillator of MINERvA by reconstructing |t | from the final state pion and muon momenta and by removing events with evidence of energetic nuclear recoil or production of other final state particles. We measure the total neutrino and antineutrino cross sections as a function of neutrino energy between 2 and 20 GeV and measure flux integrated differential cross sections as a function of Q2 , Eπ, and θπ . The Q2 dependence and equality of the neutrino and antineutrino cross sections at finite Q2 provide a confirmation of Adler's partial conservation of axial current hypothesis.

Absolute total and partial dissociative cross sections of pyrimidine at electron and proton intermediate impact velocities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wolff, Wania, E-mail: wania@if.ufrj.br; Luna, Hugo; Sigaud, Lucas

Absolute total non-dissociative and partial dissociative cross sections of pyrimidine were measured for electron impact energies ranging from 70 to 400 eV and for proton impact energies from 125 up to 2500 keV. MOs ionization induced by coulomb interaction were studied by measuring both ionization and partial dissociative cross sections through time of flight mass spectrometry and by obtaining the branching ratios for fragment formation via a model calculation based on the Born approximation. The partial yields and the absolute cross sections measured as a function of the energy combined with the model calculation proved to be a useful toolmore » to determine the vacancy population of the valence MOs from which several sets of fragment ions are produced. It was also a key point to distinguish the dissociation regimes induced by both particles. A comparison with previous experimental results is also presented.« less

Environmental influences on physical activity in rural adults: the relative contributions of home, church and work settings.

PubMed

Kegler, Michelle C; Swan, Deanne W; Alcantara, Iris; Wrensford, Louise; Glanz, Karen

2012-09-01

This study examines the relative contribution of social (eg, social support) and physical (eg, programs and facilities) aspects of worksite, church, and home settings to physical activity levels among adults in rural communities. Data are from a cross-sectional survey of 268 African American and Caucasian adults, ages 40-70, living in southwest Georgia. Separate regression models were developed for walking, moderate, vigorous, and total physical activity as measured in METs-minutes-per-week. Social support for physical activity was modest in all 3 settings (mean scores 1.5-1.9 on a 4-point scale). Participants reported limited (<1) programs and facilities for physical activity at their worksites and churches. An interaction of physical and social aspects of the home setting was observed for vigorous and moderate physical activity and total METs. There were also interactions between gender and social support at church for vigorous activity among women, and between race and the physical environment at church for moderate physical activity. A cross-over interaction was found between home and church settings for vigorous physical activity. Social support at church was associated with walking and total METs. Homes and churches may be important behavioral settings for physical activity among adults in rural communities.

Who took the "x" out of expectancy-value theory? A psychological mystery, a substantive-methodological synergy, and a cross-national generalization.

PubMed

Nagengast, Benjamin; Marsh, Herbert W; Scalas, L Francesca; Xu, Man K; Hau, Kit-Tai; Trautwein, Ulrich

2011-08-01

Expectancy-value theory (EVT) is a dominant theory of human motivation. Historically, the Expectancy × Value interaction, in which motivation is high only if both expectancy and value are high, was central to EVT. However, the Expectancy × Value interaction mysteriously disappeared from published research more than 25 years ago. Using large representative samples of 15-year-olds (N = 398,750) from 57 diverse countries, we attempted to solve this mystery by testing Expectancy × Value interactions using latent-variable models with interactions. Expectancy (science self-concept), value (enjoyment of science), and the Expectancy × Value interaction all had statistically significant positive effects on both engagement in science activities and intentions of pursuing scientific careers; these results were similar for the total sample and for nearly all of the 57 countries considered separately. This study, apparently the strongest cross-national test of EVT ever undertaken, supports the generalizability of EVT predictions--including the "lost" Expectancy × Value interaction.

Antiproton-impact ionization of hydrogen atom with Yukawa interaction

NASA Astrophysics Data System (ADS)

Jakimovski, Dragan; Grozdanov, Tasko P.; Janev, Ratko K.

2018-01-01

The process of ionization of hydrogen atom by antiproton impact is studied when the interparticle interactions in the system are described by screened interactions of Yukawa type. The collision dynamics is described by the semiclassical atomic-orbital close-coupling method in which the bound atomic states and positive energy continuum pseudostates are determined by diagonalization of target Hamiltonian in a sufficiently large even-tempered basis to ensure convergence of the results at each value of the screening length λ of the interaction. With decreasing the screening length, the bound states in the Yukawa potential become unbound, thus increasing the number of continuum pseudostates. At low collision energies, this leads to the increase of the ionization cross section. It is observed that the energies of pseudostates, generated by the exit of nl bound states in the continuum, at certain critical values λ nl c exhibit series of avoided crossings when λ is varied. The avoided crossings appear between the ( n + k) l and ( n + k + 1) l ( n = 1, 2, 3, … ; k = 0, 1, 2, …) states at screening lengths close to the critical screening length λ nl c . The avoided crossings become increasingly less pronounced with increasing n, k and l. The matrix elements for the ( n + k) l - ( n + k + 1) l transitions at the avoided crossings λ x,(n+k)l (n+k+1)l exhibit maxima and are reflected in the structure of the cross sections for population of the lower nl pseudostates. These structures are, however, smeared out in the total ionization cross section.

Effects of relativity of RTEX in collisions of U sup q+ with light targets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Mau Hsiung.

1990-11-07

We have calculated the resonant transfer and excitation cross sections in collisions of U{sup q+} (q = 82, 89, 90) ion with H{sub 2}, He and C in impulse approximation using the multi-configuration Dirac-Fock method. The calculations were carried out in intermediate coupling with configuration interaction. The quantum electrodynamic and finite nuclear size corrections were included in the calculations of transition energies. The Auger rates were calculated including the contributions from Coulomb as well as the transverse Breit interactions. For U{sup 89+} and U{sup 90+}, effects of relatively not only shift the peak positions but also change the peak structure.more » The total dielectronic recombination strength has been found to increase by 50% due to the effects of relativity. The present theoretical RTEX cross sections for U{sup 90+} in hydrogen agree well with experiment. For U{sup 82+}, Breit interaction had been found to have little effect on the RTEX cross sections involving L-shell excitation. However, the spin-orbit interaction can still make significant change in the peak structure. 24 refs., 4 figs.« less

PROBLEMS OF THE OPTICAL MODEL FOR DEUTERONS. II. EXPERIMENTS FOR DETERMINATION OF THE PARAMETERS OF THE OPTICAL POTENTIAL FOR DEUTERONS (in Polish)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grotowski, K.

1963-01-01

An experiment for determination of the parameters of the optical potential for deuterons is presented. Total reaction cross sections for the interaction of deuterons with nuclei were determined by evaluating the cross sections for the emission of charged particles and neutrons. The angular distributions for the elastic scattering of deuterons were also measured. (auth)

Extraction of In-Medium Nucleon-Nucleon Amplitude From Experiment

NASA Technical Reports Server (NTRS)

Tripathi, R. K.; Cucinotta, Francis A.; Wilson, John W.

1998-01-01

The in-medium nucleon-nucleon amplitudes are extracted from the available proton-nucleus total reaction cross sections data. The retrieval of the information from the experiment makes the estimate of reaction cross sections very reliable. Simple expressions are given for the in-medium nucleon-nucleon amplitudes for any system of colliding nuclei as a function of energy. Excellent agreement with experimental observations is demonstrated in the ion-nucleus interactions.

Measurements of the inclusive neutrino and antineutrino charged current cross sections in MINERvA using the low-ν flux method

NASA Astrophysics Data System (ADS)

Devan, J.; Ren, L.; Aliaga, L.; Altinok, O.; Bellantoni, L.; Bercellie, A.; Betancourt, M.; Bodek, A.; Budd, H.; Cai, T.; Carneiro, M. F.; da Motta, H.; Dytman, S. A.; Díaz, G. A.; Eberly, B.; Endress, E.; Felix, J.; Fields, L.; Fine, R.; Gago, A. M.; Galindo, R.; Gallagher, H.; Ghosh, A.; Gran, R.; Harris, D. A.; Higuera, A.; Hurtado, K.; Kleykamp, J.; Kordosky, M.; Le, T.; Maher, E.; Manly, S.; Mann, W. A.; Marshall, C. M.; Martinez Caicedo, D. A.; McFarland, K. S.; McGivern, C. L.; McGowan, A. M.; Messerly, B.; Miller, J.; Mislivec, A.; Morfín, J. G.; Mousseau, J.; Naples, D.; Nelson, J. K.; Norrick, A.; Nuruzzaman, Paolone, V.; Park, J.; Patrick, C. E.; Perdue, G. N.; Ramirez, M. A.; Ransome, R. D.; Ray, H.; Rimal, D.; Rodrigues, P. A.; Ruterbories, D.; Schellman, H.; Solano Salinas, C. J.; Tice, B. G.; Valencia, E.; Wolcott, J.; Wospakrik, M.; Minerva Collaboration

2016-12-01

The total cross sections are important ingredients for the current and future neutrino oscillation experiments. We present measurements of the total charged-current neutrino and antineutrino cross sections on scintillator (CH) in the NuMI low-energy beamline using an in situ prediction of the shape of the flux as a function of neutrino energy from 2-50 GeV. This flux prediction takes advantage of the fact that neutrino and antineutrino interactions with low nuclear recoil energy (ν ) have a nearly constant cross section as a function of incident neutrino energy. This measurement is the lowest energy application of the low-ν flux technique, the first time it has been used in the NuMI antineutrino beam configuration, and demonstrates that the technique is applicable to future neutrino beams operating at multi-GeV energies. The cross section measurements presented are the most precise measurements to date below 5 GeV.

Measurements of the inclusive neutrino and antineutrino charged current cross sections in MINERvA using the low- ν flux method

DOE PAGES

Devan, J.

2016-12-20

The total cross sections are important ingredients for the current and future neutrino oscillation experiments. We present measurements of the total charged-current neutrino and antineutrino cross sections on scintillator (CH) in the NuMI low-energy beamline using an in situ prediction of the shape of the flux as a function of neutrino energy from 2–50 GeV. This flux prediction takes advantage of the fact that neutrino and antineutrino interactions with low nuclear recoil energy (ν) have a nearly constant cross section as a function of incident neutrino energy. This measurement is the lowest energy application of the low-ν flux technique, the first timemore » it has been used in the NuMI antineutrino beam configuration, and demonstrates that the technique is applicable to future neutrino beams operating at multi-GeV energies. Lastly, the cross section measurements presented are the most precise measurements to date below 5 GeV.« less

Simple method for determining fullerene negative ion formation★

NASA Astrophysics Data System (ADS)

Felfli, Zineb; Msezane, Alfred Z.

2018-04-01

A robust potential wherein is embedded the crucial core-polarization interaction is used in the Regge-pole methodology to calculate low-energy electron elastic scattering total cross section for the C60 fullerene in the electron impact energy range 0.02 ≤ E ≤ 10.0 eV. The energy position of the characteristic dramatically sharp resonance appearing at the second Ramsauer-Townsend minimum of the total cross section representing stable C60 - fullerene negative ion formation agrees excellently with the measured electron affinity of C60 [Huang et al., J. Chem. Phys. 140, 224315 (2014)]. The benchmarked potential and the Regge-pole methodology are then used to calculate electron elastic scattering total cross sections for selected fullerenes, from C54 through C240. The total cross sections are found to be characterized generally by Ramsauer-Townsend minima, shape resonances and dramatically sharp resonances representing long-lived states of fullerene negative ion formation. For the total cross sections of C70, C76, C78, and C84 the agreement between the energy positions of the very sharp resonances and the measured electron affinities is outstanding. Additionally, we compare our extracted energy positions of the resultant fullerene anions from our calculated total cross sections of the C86, C90 and C92 fullerenes with the estimated electron affinities ≥3.0 eV by the experiment [Boltalina et al., Rapid Commun. Mass Spectrom. 7, 1009 (1993)]. Resonance energy positions of other fullerenes, including C180 and C240 are also obtained. Most of the total cross sections presented in this paper are the first and only; our novel approach is general and should be applicable to other fullerenes as well and complex heavy atoms, such as the lanthanide atoms. We conclude with a remark on the catalytic properties of the fullerenes through their negative ions.

Absorption effects in electron-sulfur-dioxide collisions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Machado, L. E.; Sugohara, R. T.; Santos, A. S. dos

2011-09-15

A joint experimental-theoretical study on electron-SO{sub 2} collisions in the low and intermediate energy range is reported. More specifically, experimental elastic differential, integral, and momentum transfer cross sections in absolute scale are measured in the 100-1000 eV energy range using the relative-flow technique. Calculated elastic differential, integral, and momentum transfer cross sections as well as grand-total and total absorption cross sections are also presented in the 1-1000 eV energy range. A complex optical potential is used to represent the electron-molecule interaction dynamics, whereas the Schwinger variational iterative method combined with the distorted-wave approximation is used to solve the scattering equations.more » Comparison of the present results is made with the theoretical and experimental results available in the literature.« less

Collision cross sections and diffusion parameters for H and D in atomic oxygen. [in upper earth and Venus atmospheres

NASA Technical Reports Server (NTRS)

Hodges, R. R., Jr.

1993-01-01

Modeling the behavior of H and D in planetary exospheres requires detailed knowledge of the differential scattering cross sections for all of the important neutral-neutral and ion-neutral collision processes affecting these species over their entire ranges of interaction energies. In the upper atmospheres of Earth, Venus, and other planets as well, the interactions of H and D with atomic oxygen determine the rates of diffusion of escaping hydrogen isotopes through the thermosphere, the velocity distributions of exospheric atoms that encounter the upper thermosphere, the lifetimes of exospheric orbiters with periapsides near the exobase, and the transfer of momentum in collisions with hot O. The nature of H-O and D-O collisions and the derivation of a data base consisting of phase shifts and the differential, total, and momentum transfer cross sections for these interactions in the energy range 0.001 - 10 eV are discussed. Coefficients of mutual diffusion and thermal diffusion factors are calculated for temperatures of planetary interest.

Investigation of total cross sections for reactions induced by {sup 6}He interaction with silicon nuclei at energies between 5 and 50 MeV/A

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kabdrakhimova, G. D., E-mail: gaukharkd@gmail.com; Sobolev, Yu. G.; Kuhtina, I. N.

2017-01-15

Experimental excitation functions in terms of the total cross sections for {sup 6}He + Si nuclear reactions are analyzed in the energy range between 5 and 50 MeV/A, and a brief survey of the procedures used to obtain experimental data is given. Particular attention is given to describing experiments performed in beams of radioactive nuclei from the accelerators of the Laboratory of Nuclear Reactions at the Joint Institute for Nuclear Research (JINR, Dubna). The experimental data in question are analyzed on the basis of a semimicroscopic optical model.

Calculated stopping powers of low-energy electrons in some materials of interest in radiation protection.

PubMed

Akande, W

1993-03-01

Stopping powers of low-energy (< 10 keV) electrons in aluminum, copper, cesium, barium, lead, lithium, and uranium were calculated using an analytic method. The interaction of the electrons with the materials were characterized in terms of three cross sections for total ionization and total scattering. Experimental cross section data were collated, where available, for the materials. The expressions were then fitted to the data to obtain the values of the relevant constants in the expressions. This enabled the basic equation of stopping powers of electrons to be evaluated for the materials. Comparison of the results obtained with those of other workers was affected.

Proton-impact ionization cross sections of adenine measured at 0.5 and 2.0 MeV by electron spectroscopy

NASA Astrophysics Data System (ADS)

Iriki, Y.; Kikuchi, Y.; Imai, M.; Itoh, A.

2011-11-01

Double-differential ionization cross sections (DDCSs) of vapor-phase adenine molecules (C5H5N5) by 0.5- and 2.0-MeV proton impact have been measured by the electron spectroscopy method. Electrons ejected from adenine were analyzed by a 45∘ parallel-plate electrostatic spectrometer over an energy range of 1.0-1000 eV at emission angles from 15∘ to 165∘. Single-differential cross sections (SDCSs) and total ionization cross sections (TICSs) were also deduced. It was found from the Platzman plot, defined as SDCSs divided by the classical Rutherford knock-on cross sections per target electron, that the SDCSs at higher electron energies are proportional to the total number of valence electrons (50) of adenine, while those at low-energy electrons are highly enhanced due to dipole and higher-order interactions. The present results of TICS are in fairly good agreement with recent classical trajectory Monte Carlo calculations, and moreover, a simple analytical formula gives nearly equivalent cross sections in magnitude at the incident proton energies investigated.

Event Generators for Simulating Heavy Ion Interactions of Interest in Evaluating Risks in Human Spaceflight

NASA Technical Reports Server (NTRS)

Wilson, Thomas L.; Pinsky, Lawrence; Andersen, Victor; Empl, Anton; Lee, Kerry; Smirmov, Georgi; Zapp, Neal; Ferrari, Alfredo; Tsoulou, Katerina; Roesler, Stefan;

Total Reaction Cross Section Excitation Function Studies for 6He Interaction with 181Ta, 59Co, natSi, 9Be Nuclei

NASA Astrophysics Data System (ADS)

Sobolev, Yu. G.; Penionzhkevich, Yu. E.; Borcea, C.; Demekhina, N. A.; Eshanov, A. G.; Ivanov, M. P.; Kabdrakhimova, G. D.; Kabyshev, A. M.; Kugler, A.; Kuterbekov, K. A.; Lukyanov, K. V.; Maj, A.; Maslov, V. A.; Negret, A.; Skobelev, N. K.; Testov, D.; Trzaska, W. H.; Voskobojnik, E. I.; Zemlyanaya, E. V.

2015-06-01

Total reaction cross section excitation functions σR(E) were measured for 6He secondary beam particles on 181Ta, 59Co, natSi and 9Be targets in a wide energy range by direct and model-independent method. This experimental method was based on prompt n-γ 4π-technique applied in event-by event mode. A high efficiency CsI(Tl) γ-spectrometer was used for the detection of reaction products (prompt γ-quanta and neutrons) accompanying each reaction event. Using the ACCULINNA fragment-separator 6He fragments (produced by 11B primary beam with 9Be target) are separated and transported to n-γ shielded experimental cave at FLNR JINR. The measured total reaction cross section data σR(E) for the above mentioned reactions are compared with a theoretical calculation based on the optical potential with the real part having the double-folding form.

Strongly interacting photons in asymmetric quantum well via resonant tunneling.

PubMed

Sun, H; Fan, S L; Feng, X L; Wu, C F; Gong, S Q; Huang, G X; Oh, C H

2012-04-09

We propose an asymmetric quantum well structure to realize strong interaction between two slow optical pulses. The essential idea is the combination of the advantages of inverted-Y type scheme and resonant tunneling. We analytically demonstrate that giant cross-Kerr nonlinearity can be achieved with vanishing absorptions. Owing to resonant tunneling, the contributions of the probe and signal cross-Kerr nonlinearities to total nonlinear phase shift vary from destructive to constrictive, leading to nonlinear phase shift on order of π at low light level. In this structure, the scheme is inherent symmetric for the probe and signal pulses. Consequently, the condition of group velocity matching can be fulfilled with appropriate initial electron distribution.

Final-state interactions in semi-inclusive deep inelastic scattering off the Deuteron

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wim Cosyn, Misak Sargsian

2011-07-01

Semi-inclusive deep inelastic scattering off the Deuteron with production of a slow nucleon in recoil kinematics is studied in the virtual nucleon approximation, in which the final state interaction (FSI) is calculated within general eikonal approximation. The cross section is derived in a factorized approach, with a factor describing the virtual photon interaction with the off-shell nucleon and a distorted spectral function accounting for the final-state interactions. One of the main goals of the study is to understand how much the general features of the diffractive high energy soft rescattering accounts for the observed features of FSI in deep inelasticmore » scattering (DIS). Comparison with the Jefferson Lab data shows good agreement in the covered range of kinematics. Most importantly, our calculation correctly reproduces the rise of the FSI in the forward direction of the slow nucleon production angle. By fitting our calculation to the data we extracted the W and Q{sup 2} dependences of the total cross section and slope factor of the interaction of DIS products, X, off the spectator nucleon. This analysis shows the XN scattering cross section rising with W and decreasing with an increase of Q{sup 2}. Finally, our analysis points at a largely suppressed off-shell part of the rescattering amplitude.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

dos Reis, Alberto Correa

This work a presents a measurement of the total cross section for the charmed baryonmore » $$\\Lambda_c$$ times the branching fraction of the mode $$\\Lambda_c \\to pK\\bar{\\mu}$$, for the kinematical region $$x_F$$ > O in $$\\pi$$-nucleus interactions at 250 GeV/c. This measurement is made with data from the experiment E769, collected during 1987/1988 at the FERMILAB Tagged Photon Laboratory. A segmented target of berillium, aluminum, copper and tungsten was used. Based on the A dependence measurement, made by E769, and on the available branching fractions, the total cross section per nucleon is calculated. The result is compared with other experiments and with some theoretical predictions inspired on QCD.« less

Polymorphisms of the TNF-α gene interact with plasma fatty acids on inflammatory biomarker profile: a population-based, cross-sectional study in São Paulo, Brazil.

PubMed

Oki, Erica; Norde, Marina N; Carioca, Antônio A F; Souza, José M P; Castro, Inar A; Marchioni, Dirce M L; Fisberg, Regina M; Rogero, Marcelo M

2017-06-01

The aim of the present study was to investigate the relationship of four TNF-α SNP with inflammatory biomarkers and plasma fatty acids (FA), and the interaction among them in a population-based, cross-sectional study in São Paulo, Brazil. A total of 281 subjects, aged >19 and <60 years, participated in a cross-sectional, population-based study performed in Brazil. The following SNP spanning the TNF-α gene were genotyped: -238G/A (rs361525), -308G/A (rs1800629), -857C/T (rs1799724) and -1031T/C (rs1799964). In all, eleven plasma inflammatory biomarkers and plasma FA profile were determined. To analyse the interaction between TNF-α SNP and plasma FA, a cluster analysis was performed to stratify individuals based on eleven inflammatory biomarkers into two groups used as outcome: inflammatory (INF) and non-inflammatory clusters. The -238A allele carriers had higher TNF-α (P=0·033), IL-6 (P=0·013), IL-1β (P=0·037), IL-12 (0·048) and IL-10 (P=0·010) than the GG genotype. The -308A allele carriers also had lower levels of plasma palmitoleic acid (P=0·009), oleic acid (P=0·039), total MUFA (P=0·014), stearoyl-CoA desaturase (SCD) activity index-16 (P=0·007), SCD-18 (P=0·020) and higher levels of PUFA (P=0·046) and DHA (P=0·044). Significant interactions modifying the risk of belonging to the INF cluster were observed with inflammatory cluster as outcome between -857C/T and plasma α-linolenic acid (P=0·026), and also between -308G/A and plasma stearic acid (P=0·044) and total SFA (P=0·040). Our study contributes to knowledge on TNF-α SNP and their association with inflammatory biomarker levels, plasma FA and the interaction among them, of particular interest for the Brazilian population.

Secondary neutron-production cross sections from heavy-ioninteractions in composite targets.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heilbronn, L.; Iwata, Y.; Iwase,H.

Secondary neutron-production cross-sections have been measured from interactions of 290 MeV/nucleon C and 600 MeV/nucleon Ne in a target composed of simulated Martian regolith and polyethylene, and from 400 MeV/nucleon Ne interactions in wall material from the International Space Station. The data were measured between 5 and 80 deg in the laboratory. We report the double-differential cross sections, angular distributions, and total neutron-production cross sections from all three systems. The spectra from all three systems exhibit behavior previously reported in other heavy-ion, neutron production experiments; namely, a peak at forward angles near the energy corresponding to the beam velocity, withmore » the remaining spectra generated by pre-equilibrium and equilibrium processes. The double differential cross sections are fitted with a moving-source parameterization. Also reported are the data without corrections for neutron flux attenuation in the target and other intervening materials, and for neutron production in non-target materials near the target position. These uncorrected spectra are compared with SHIELD-HIT and PHITS transport model calculations. The transport model calculations reproduce the spectral shapes well, but, on average, underestimate the magnitudes of the cross sections.« less

Measurement of total and differential cross sections of neutrino and antineutrino coherent π ± production on carbon

DOE PAGES

Mislivec, A.; Higuera, A.; Aliaga, L.; ...

2018-02-28

Neutrino induced coherent charged pion production on nuclei,more » $$\\overline{v}μA$$→μ ±π ∓A, is a rare inelastic interaction in which the four-momentum squared transferred to the nucleus is nearly zero, leaving it intact. We identify such events in the scintillator of MINERvA by reconstructing |t| from the final state pion and muon momenta and by removing events with evidence of energetic nuclear recoil or production of other final state particles. We measure the total neutrino and antineutrino cross sections as a function of neutrino energy between 2 and 20 GeV and measure flux integrated differential cross sections as a function of Q 2, E π, and θ π. The Q 2 dependence and equality of the neutrino and antineutrino cross sections at finite Q 2 provide a confirmation of Adler’s partial conservation of axial current hypothesis.« less

Coherent single pion production by antineutrino charged current interactions and test of PCAC

NASA Astrophysics Data System (ADS)

Marage, P.; Aderholz, M.; Allport, P.; Armenise, N.; Baton, J. P.; Berggren, M.; Bertrand, D.; Brisson, V.; Bullock, F. W.; Burkot, W.; Calicchio, M.; Clayton, E. F.; Coghen, T.; Cooper-Sarkar, A. M.; Erriquez, O.; Fitch, P. J.; Gerbier, G.; Guy, J.; Hamisi, F.; Hulth, P. O.; Jones, G. T.; Kasper, P.; Klein, H.; Middleton, R. P.; Miller, D. B.; Mobayyen, M. M.; Morrison, D. R. O.; Natali, S.; Neveu, M.; O'Neale, S. W.; Parker, M. A.; Petiau, P.; Sacton, J.; Sansum, R. A.; Simopoulou, E.; Vallée, C.; Varvell, K.; Vayaki, A.; Venus, W.; Wachsmuth, H.; Wells, J.; Wittek, W.

1986-06-01

The cross section for coherent production of a single π- meson in charged current antineutrino interactions on neon nuclei has been measured in BEBC to be (175±25) 10-40 cm2/neon nucleus, averaged over the energy spectrum of the antineutrino wide band beam at the CERN SPS; this corresponds to (0.9±0.1) % of the total charged currentbar v_μ cross section. The distributions of kinematical variables are in agreement with theoretical predictions based on the PCAC hypothesis and the meson dominance model; in particular, the Q 2 dependence is well described by a propagator containing a mass m=(1.35±0.18) GeV. The absolute value of the cross section is also in agreement with the model. This analysis thus provides a test of the PCAC hypothesis in the antineutrino energy range 5 150 GeV.

Measurement of the cross section for prompt isolated diphoton production using the full CDF run II data sample.

PubMed

Aaltonen, T; Amerio, S; Amidei, D; Anastassov, A; Annovi, A; Antos, J; Apollinari, G; Appel, J A; Arisawa, T; Artikov, A; Asaadi, J; Ashmanskas, W; Auerbach, B; Aurisano, A; Azfar, F; Badgett, W; Bae, T; Barbaro-Galtieri, A; Barnes, V E; Barnett, B A; Barria, P; Bartos, P; Bauce, M; Bedeschi, F; Behari, S; Bellettini, G; Bellinger, J; Benjamin, D; Beretvas, A; Bhatti, A; Bland, K R; Blumenfeld, B; Bocci, A; Bodek, A; Bortoletto, D; Boudreau, J; Boveia, A; Brigliadori, L; Bromberg, C; Brucken, E; Budagov, J; Budd, H S; Burkett, K; Busetto, G; Bussey, P; Butti, P; Buzatu, A; Calamba, A; Camarda, S; Campanelli, M; Canelli, F; Carls, B; Carlsmith, D; Carosi, R; Carrillo, S; Casal, B; Casarsa, M; Castro, A; Catastini, P; Cauz, D; Cavaliere, V; Cavalli-Sforza, M; Cerri, A; Cerrito, L; Chen, Y C; Chertok, M; Chiarelli, G; Chlachidze, G; Cho, K; Chokheli, D; Ciocci, M A; Clark, A; Clarke, C; Convery, M E; Conway, J; Corbo, M; Cordelli, M; Cox, C A; Cox, D J; Cremonesi, M; Cruz, D; Cuevas, J; Culbertson, R; d'Ascenzo, N; Datta, M; De Barbaro, P; Demortier, L; Deninno, M; Devoto, F; d'Errico, M; Di Canto, A; Di Ruzza, B; Dittmann, J R; D'Onofrio, M; Donati, S; Dorigo, M; Driutti, A; Ebina, K; Edgar, R; Elagin, A; Erbacher, R; Errede, S; Esham, B; Eusebi, R; Farrington, S; Fernández Ramos, J P; Field, R; Flanagan, G; Forrest, R; Franklin, M; Freeman, J C; Frisch, H; Funakoshi, Y; Garfinkel, A F; Garosi, P; Gerberich, H; Gerchtein, E; Giagu, S; Giakoumopoulou, V; Gibson, K; Ginsburg, C M; Giokaris, N; Giromini, P; Giurgiu, G; Glagolev, V; Glenzinski, D; Gold, M; Goldin, D; Golossanov, A; Gomez, G; Gomez-Ceballos, G; Goncharov, M; González López, O; Gorelov, I; Goshaw, A T; Goulianos, K; Gramellini, E; Grinstein, S; Grosso-Pilcher, C; Group, R C; Guimaraes da Costa, J; Hahn, S R; Han, J Y; Happacher, F; Hara, K; Hare, M; Harr, R F; Harrington-Taber, T; Hatakeyama, K; Hays, C; Heinrich, J; Herndon, M; Hocker, A; Hong, Z; Hopkins, W; Hou, S; Hughes, R E; Husemann, U; Huston, J; Introzzi, G; Iori, M; Ivanov, A; James, E; Jang, D; Jayatilaka, B; Jeon, E J; Jindariani, S; Jones, M; Joo, K K; Jun, S Y; Junk, T R; Kambeitz, M; Kamon, T; Karchin, P E; Kasmi, A; Kato, Y; Ketchum, W; Keung, J; Kilminster, B; Kim, D H; Kim, H S; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kim, Y J; Kimura, N; Kirby, M; Knoepfel, K; Kondo, K; Kong, D J; Konigsberg, J; Kotwal, A V; Kreps, M; Kroll, J; Kruse, M; Kuhr, T; Kurata, M; Laasanen, A T; Lammel, S; Lancaster, M; Lannon, K; Latino, G; Lee, H S; Lee, J S; Leo, S; Leone, S; Lewis, J D; Limosani, A; Lipeles, E; Liu, H; Liu, Q; Liu, T; Lockwitz, S; Loginov, A; Lucchesi, D; Lueck, J; Lujan, P; Lukens, P; Lungu, G; Lys, J; Lysak, R; Madrak, R; Maestro, P; Malik, S; Manca, G; Manousakis-Katsikakis, A; Margaroli, F; Marino, P; Martínez, M; Matera, K; Mattson, M E; Mazzacane, A; Mazzanti, P; McNulty, R; Mehta, A; Mehtala, P; Mesropian, C; Miao, T; Mietlicki, D; Mitra, A; Miyake, H; Moed, S; Moggi, N; Moon, C S; Moore, R; Morello, M J; Mukherjee, A; Muller, Th; Murat, P; Mussini, M; Nachtman, J; Nagai, Y; Naganoma, J; Nakano, I; Napier, A; Nett, J; Neu, C; Nigmanov, T; Nodulman, L; Noh, S Y; Norniella, O; Oakes, L; Oh, S H; Oh, Y D; Oksuzian, I; Okusawa, T; Orava, R; Ortolan, L; Pagliarone, C; Palencia, E; Palni, P; Papadimitriou, V; Parker, W; Pauletta, G; Paulini, M; Paus, C; Phillips, T J; Piacentino, G; Pianori, E; Pilot, J; Pitts, K; Plager, C; Pondrom, L; Poprocki, S; Potamianos, K; Prokoshin, F; Pranko, A; Ptohos, F; Punzi, G; Ranjan, N; Redondo Fernández, I; Renton, P; Rescigno, M; Riddick, T; Rimondi, F; Ristori, L; Robson, A; Rodriguez, T; Rolli, S; Ronzani, M; Roser, R; Rosner, J L; Ruffini, F; Ruiz, A; Russ, J; Rusu, V; Safonov, A; Sakumoto, W K; Sakurai, Y; Santi, L; Sato, K; Saveliev, V; Savoy-Navarro, A; Schlabach, P; Schmidt, E E; Schwarz, T; Scodellaro, L; Scuri, F; Seidel, S; Seiya, Y; Semenov, A; Sforza, F; Shalhout, S Z; Shears, T; Shepard, P F; Shimojima, M; Shochet, M; Shreyber-Tecker, I; Simonenko, A; Sinervo, P; Sliwa, K; Smith, J R; Snider, F D; Sorin, V; Song, H; Stancari, M; St Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Sudo, Y; Sukhanov, A; Suslov, I; Takemasa, K; Takeuchi, Y; Tang, J; Tecchio, M; Teng, P K; Thom, J; Thomson, E; Thukral, V; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Torre, S; Torretta, D; Totaro, P; Trovato, M; Ukegawa, F; Uozumi, S; Vázquez, F; Velev, G; Vellidis, C; Vernieri, C; Vidal, M; Vilar, R; Vizán, J; Vogel, M; Volpi, G; Wagner, P; Wallny, R; Wang, S M; Warburton, A; Waters, D; Wester, W C; Whiteson, D; Wicklund, A B; Wilbur, S; Williams, H H; Wilson, J S; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, H; Wright, T; Wu, X; Wu, Z; Yamamoto, K; Yamato, D; Yang, T; Yang, U K; Yang, Y C; Yao, W-M; Yeh, G P; Yi, K; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Zanetti, A M; Zeng, Y; Zhou, C; Zucchelli, S

2013-03-08

This Letter reports a measurement of the cross section for producing pairs of central prompt isolated photons in proton-antiproton collisions at a total energy sqrt[s] = 1.96 TeV using data corresponding to 9.5 fb(-1) integrated luminosity collected with the CDF II detector at the Fermilab Tevatron. The measured differential cross section is compared to three calculations derived from the theory of strong interactions. These include a prediction based on a leading order matrix element calculation merged with a parton shower model, a next-to-leading order calculation, and a next-to-next-to-leading order calculation. The first and last calculations reproduce most aspects of the data, thus showing the importance of higher-order contributions for understanding the theory of strong interaction and improving measurements of the Higgs boson and searches for new phenomena in diphoton final states.

Neutrino-nucleus interactions at the LBNF near detector

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mosel, Ulrich

2015-10-15

The reaction mechanisms for neutrino interactions with an {sup 40}Ar nucleus with the LBNF flux are calculated with the Giessen-Boltzmann-Uehling-Uhlenbeck (GiBUU) transport-theoretical implementation of these interactions. Quasielastic scattering, many-body effects, pion production and absorption and Deep Inelastic Scattering are discussed; they all play a role at the LBNF energies and are experimentally entangled with each other. Quasielastic scattering makes up for only about 1/3 of the total cross section whereas pion production channels make up about 2/3 of the total. This underlines the need for a consistent description of the neutrino-nucleus reaction that treats all channels on an equal, consistentmore » footing. The results discussed here can also serve as useful guideposts for the Intermediate Neutrino Program.« less

Elastic scattering and soft diffraction with ALFA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Puzo, P.

The ALFA detector in ATLAS aims at measuring the absolute luminosity and the total cross-section with 2-3% accuracy. Its uses elastically scattered protons whose impact position on a fiber detector, located 240 m away from the interaction point, allow a measurement of the scattering angle.

Search for Dark Matter Interactions using Ionization Yield in Liquid Xenon

NASA Astrophysics Data System (ADS)

Uvarov, Sergey

Cosmological observations overwhelmingly support the existence of dark matter which constitutes 87% of the universe's total mass. Weakly Interacting Massive Particles (WIMPs) are a prime candidate for dark matter, and the Large Underground Xenon (LUX) experiment aims to a direct-detection of a WIMP-nucleon interaction. The LUX detector is a dual-phase xenon time-projection chamber housed 4,850 feet underground at Sanford Underground Research Facility in Lead, South Dakota. We present the ionization-only analysis of the LUX 2013 WIMP search data. In the 1.04 x 104 kg-days exposure, thirty events were observed out of the 24.8 expected from radioactive backgrounds. We employ a cut-and-count method to set a 1-sided 90% C.L. upper limit for spin-independent WIMP-nucleon cross-sections. A zero charge yield for nuclear-recoils below 0.7 keV is included upper limit calculation. This ionization-only analysis excludes an unexplored region of WIMP-nucleon cross-section for low-mass WIMPs achieving 1.56 x 10-43 cm2 WIMP-nucleon cross-section exclusion for a 5.1 GeV/ c2 WIMP.

Effect of molecular anisotropy on beam scattering measurements

NASA Technical Reports Server (NTRS)

Goldflam, R.; Green, S.; Kouri, D. J.; Monchick, L.

1978-01-01

Within the energy sudden approximation, the total integral and total differential scattering cross sections are given by the angle average of scattering cross sections computed at fixed rotor orientations. Using this formalism the effect of molecular anisotropy on scattering of He by HCl and by CO is examined. Comparisons with accurate close coupling calculations indicate that this approximation is quite reliable, even at very low collision energies, for both of these systems. Comparisons are also made with predictions based on the spherical average of the interaction. For HCl the anisotropy is rather weak and its main effect is a slight quenching of the oscillations in the differential cross sections relative to predictions of the spherical averaged potential. For CO the anisotropy is much stronger, so that the oscillatory pattern is strongly quenched and somewhat shifted. It appears that the sudden approximation provides a simple yet accurate method for describing the effect of molecular anisotropy on scattering measurements.

Hydrotropism and its interaction with gravitropism in maize roots

NASA Technical Reports Server (NTRS)

Takahashi, H.; Scott, T. K.

1991-01-01

We have partially characterized root hydrotropism and its interaction with gravitropism in maize (Zea mays L.). Roots of Golden Cross Bantam 70, which require light for orthogravitropism, showed positive hydrotropism; bending upward when placed horizontally below a hydrostimulant (moist cheesecloth) in 85% relative humidity (RH) and in total darkness. However, the light-exposed roots of Golden Cross Bantam 70 or roots of a normal maize cultivar, Burpee Snow Cross, showed positive gravitropism under the same conditions; bending downward when placed horizontally below the hydrostimulant in 85% RH. Light-exposed roots of Golden Cross Bantam 70 placed at 70 degrees below the horizontal plane responded positively hydrotropically, but gravitropism overcame the hydrotropism when the roots were placed at 45 degrees below the horizontal. Roots placed vertically with the tip down in 85% RH bent to the side toward the hydrostimulant in both cultivars, and light conditions did not affect the response. Such vertical roots did not respond when the humidity was maintained near saturation. These results suggest that hydrotropic and gravitropic responses interact with one another depending on the intensity of one or both factors. Removal of the approximately 1.5 millimeter root tip blocked both hydrotropic and gravitropic responses in the two cultivars. However, removal of visible root tip mucilage did not affect hydrotropism or gravitropism in either cultivar.

Cross-section measurement for quasi-elastic production of charmed baryons in νN interactions

NASA Astrophysics Data System (ADS)

Kayis-Topaksu, A.; Onengüt, G.; van Dantzig, R.; de Jong, M.; Melzer, O.; Oldeman, R. G. C.; Pesen, E.; Spada, F. R.; Visschers, J. L.; Güler, M.; Köse, U.; Serin-Zeyrek, M.; Sever, R.; Tolun, P.; Zeyrek, M. T.; Catanesi, M. G.; de Serio, M.; Ieva, M.; Muciaccia, M. T.; Radicioni, E.; Simone, S.; Bülte, A.; Winter, K.; van de Vyver, B.; Vilain, P.; Wilquet, G.; Pittoni, G. L.; Saitta, B.; di Capua, E.; Ogawa, S.; Shibuya, H.; Artamonov, A.; Chizhov, M.; Doucet, M.; Hristova, I. R.; Kawamura, T.; Kolev, D.; Meinhard, H.; Panman, J.; Papadopoulos, I. M.; Ricciardi, S.; Rozanov, A.; Tsenov, R.; Uiterwijk, J. W. E.; Zucchelli, P.; Goldberg, J.; Chikawa, M.; Arik, E.; Song, J. S.; Yoon, C. S.; Kodama, K.; Ushida, N.; Aoki, S.; Hara, T.; Delbar, T.; Favart, D.; Grégoire, G.; Kalinin, S.; Maklioueva, I.; Gorbunov, P.; Khovansky, V.; Shamanov, V.; Tsukerman, I.; Bruski, N.; Frekers, D.; Hoshino, K.; Kawada, J.; Komatsu, M.; Miyanishi, M.; Nakamura, M.; Nakano, T.; Narita, K.; Niu, K.; Niwa, K.; Nonaka, N.; Sato, O.; Toshito, T.; Buontempo, S.; Cocco, A. G.; D'Ambrosio, N.; de Lellis, G.; De Rosa, G.; di Capua, F.; Ereditato, A.; Fiorillo, G.; Marotta, A.; Messina, M.; Migliozzi, P.; Pistillo, C.; Scotto Lavina, L.; Strolin, P.; Tioukov, V.; Nakamura, K.; Okusawa, T.; Dore, U.; Loverre, P. F.; Ludovici, L.; Righini, P.; Rosa, G.; Santacesaria, R.; Satta, A.; Barbuto, E.; Bozza, C.; Grella, G.; Romano, G.; Sirignano, C.; Sorrentino, S.; Sato, Y.; Tezuka, I.; CHORUS Collaboration

2003-11-01

A study of quasi-elastic production of charmed baryons in charged-current interactions of neutrinos with the nuclear emulsion target of CHORUS is presented. In a sample of about 46 000 interactions located in the emulsion, candidates for decays of short-lived particles were identified by using new automatic scanning systems and later confirmed through visual inspection. Criteria based both on the topological and kinematical characteristics of quasi-elastic charm production allowed a clear separation between events of this type and those in which charm is produced in deep inelastic processes. A final sample containing 13 candidates consistent with quasi-elastic production of a charmed baryon with an estimated background of 1.7 events was obtained. At the average neutrino energy of 27 GeV the cross-section for the total quasi-elastic production of charmed baryons relative to the νN charged-current cross-section was measured to be σ(QE)/σ(CC)=(0.23+0.12-0.06(stat)+0.02-0.03(syst))×10-2. Through an analysis of the topology at the production and decay vertices the relative cross-sections were measured separately for singly (Λc+,Σc+,Σc+∗) and doubly (Σc++,Σc++∗) charged baryons.

Study of p-4He total reaction cross-section using Glauber and Coulomb-modified Glauber models

NASA Astrophysics Data System (ADS)

Tag El-Din, Ibrahim M. A.; Taha, M. M.; Hassan, Samia S. A.

2014-02-01

The total nuclear reaction cross-section σR for p-4He in the energy range from 25 MeV to 1000 MeV is calculated within Glauber and Coulomb-modified Glauber models. The Coulomb-modified Glauber model (CMGM) is introduced via modification of the Coulomb trajectory of the projectile from a straight line, and calculation of the effective radius of interaction. The effects of in-medium nucleon-nucleon (NN) total cross-section, phase variation, high order momentum transfer component of nucleon-nucleon elastic scattering amplitude and Pauli blocking are studied. It is pointed out that the phase variation of the nucleon-nucleon amplitude plays a significant role in describing σR with γ = -1.6 fm2 at in-medium nuclear density ϱ = 0 and γ = -2 fm2 at ϱ = 0.17 fm-3 in the whole energy range. A remarkable fit to the available experimental data is obtained by invoking Pauli blocking and high order momentum transfer of nucleon-nucleon (NN) elastic scattering amplitude for Ep < 100 MeV.

Measurements of the Total Reaction Cross Sections for 6,8He and 8,9Li Nuclei with Energies of (25-45)A Mev on natAl, natTa and natPb

NASA Astrophysics Data System (ADS)

Erdemchimeg, B.; Artukh, A. G.; Klygin, S. A.; Kononenko, G. A.; Kyslukha, D. A.; Sereda, Yu. M.; Vorontzov, A. N.; Lukyanov, S. M.; Penionzhkevich, Yu. E.; Davaa, S.; Khuukhenkhuu, G.; Borcea, C.; Rotaru, F.; Stanoiu, M.; Martina, L.; Saillant, F.; Raine, B.

2015-06-01

The total nuclear reaction cross sections (σR) measurements have long been of interest since they tell us about the radii and transparency of these nuclei and give clues to understanding of their structure. For studies of unstable nuclei, in particular the physical properties of halo nuclei and the neutron skin thickness, it is valuable to know not only the root-mean-square radii (rms) but it is important to know the details of nucleusnucleus potentials. Our goal was to study total reaction cross sections (σR) by a direct measurement technique (the so-called beam attenuation or transmission method) which allows to extract model independent information. The interaction radii for 6He, 8,9Li were extracted, which are in agreement with the previous measurement at the similar energies (about a few tens of AMeV) Our results show a tendency of increasing radii as function of mass of the secondary targets.

Universal Parameterization of Absorption Cross Sections

NASA Technical Reports Server (NTRS)

Tripathi, R. K.; Cucinotta, Francis A.; Wilson, John W.

1997-01-01

This paper presents a simple universal parameterization of total reaction cross sections for any system of colliding nuclei that is valid for the entire energy range from a few AMeV to a few AGeV. The universal picture presented here treats proton-nucleus collision as a special case of nucleus-nucleus collision, where the projectile has charge and mass number of one. The parameters are associated with the physics of the collision system. In general terms, Coulomb interaction modifies cross sections at lower energies, and the effects of Pauli blocking are important at higher energies. The agreement between the calculated and experimental data is better than all earlier published results.

First measurement of the νμ charged-current cross section on a water target without pions in the final state

NASA Astrophysics Data System (ADS)

Abe, K.; Amey, J.; Andreopoulos, C.; Antonova, M.; Aoki, S.; Ariga, A.; Ashida, Y.; Ban, S.; Barbi, M.; Barker, G. J.; Barr, G.; Barry, C.; Batkiewicz, M.; Berardi, V.; Berkman, S.; Bhadra, S.; Bienstock, S.; Blondel, A.; Bolognesi, S.; Bordoni, S.; Boyd, S. B.; Brailsford, D.; Bravar, A.; Bronner, C.; Buizza Avanzini, M.; Calland, R. G.; Campbell, T.; Cao, S.; Cartwright, S. L.; Catanesi, M. G.; Cervera, A.; Chappell, A.; Checchia, C.; Cherdack, D.; Chikuma, N.; Christodoulou, G.; Coleman, J.; Collazuol, G.; Coplowe, D.; Cudd, A.; Dabrowska, A.; De Rosa, G.; Dealtry, T.; Denner, P. F.; Dennis, S. R.; Densham, C.; Di Lodovico, F.; Dolan, S.; Drapier, O.; Duffy, K. E.; Dumarchez, J.; Dunne, P.; Emery-Schrenk, S.; Ereditato, A.; Feusels, T.; Finch, A. J.; Fiorentini, G. A.; Friend, M.; Fujii, Y.; Fukuda, D.; Fukuda, Y.; Garcia, A.; Giganti, C.; Gizzarelli, F.; Golan, T.; Gonin, M.; Hadley, D. R.; Haegel, L.; Haigh, J. T.; Hansen, D.; Harada, J.; Hartz, M.; Hasegawa, T.; Hastings, N. C.; Hayashino, T.; Hayato, Y.; Hillairet, A.; Hiraki, T.; Hiramoto, A.; Hirota, S.; Hogan, M.; Holeczek, J.; Hosomi, F.; Huang, K.; Ichikawa, A. K.; Ikeda, M.; Imber, J.; Insler, J.; Intonti, R. A.; Ishida, T.; Ishii, T.; Iwai, E.; Iwamoto, K.; Izmaylov, A.; Jamieson, B.; Jiang, M.; Johnson, S.; Jonsson, P.; Jung, C. K.; Kabirnezhad, M.; Kaboth, A. C.; Kajita, T.; Kakuno, H.; Kameda, J.; Karlen, D.; Katori, T.; Kearns, E.; Khabibullin, M.; Khotjantsev, A.; Kim, H.; Kim, J.; King, S.; Kisiel, J.; Knight, A.; Knox, A.; Kobayashi, T.; Koch, L.; Koga, T.; Koller, P. P.; Konaka, A.; Kormos, L. L.; Koshio, Y.; Kowalik, K.; Kudenko, Y.; Kurjata, R.; Kutter, T.; Lagoda, J.; Lamont, I.; Lamoureux, M.; Lasorak, P.; Laveder, M.; Lawe, M.; Licciardi, M.; Lindner, T.; Liptak, Z. J.; Litchfield, R. P.; Li, X.; Longhin, A.; Lopez, J. P.; Lou, T.; Ludovici, L.; Lu, X.; Magaletti, L.; Mahn, K.; Malek, M.; Manly, S.; Maret, L.; Marino, A. D.; Martin, J. F.; Martins, P.; Martynenko, S.; Maruyama, T.; Matveev, V.; Mavrokoridis, K.; Ma, W. Y.; Mazzucato, E.; McCarthy, M.; McCauley, N.; McFarland, K. S.; McGrew, C.; Mefodiev, A.; Metelko, C.; Mezzetto, M.; Minamino, A.; Mineev, O.; Mine, S.; Missert, A.; Miura, M.; Moriyama, S.; Morrison, J.; Mueller, Th. A.; Nakadaira, T.; Nakahata, M.; Nakamura, K. G.; Nakamura, K.; Nakamura, K. D.; Nakanishi, Y.; Nakayama, S.; Nakaya, T.; Nakayoshi, K.; Nantais, C.; Nielsen, C.; Nishikawa, K.; Nishimura, Y.; Novella, P.; Nowak, J.; O'Keeffe, H. M.; Okumura, K.; Okusawa, T.; Oryszczak, W.; Oser, S. M.; Ovsyannikova, T.; Owen, R. A.; Oyama, Y.; Palladino, V.; Palomino, J. L.; Paolone, V.; Patel, N. D.; Paudyal, P.; Pavin, M.; Payne, D.; Petrov, Y.; Pickering, L.; Pinzon Guerra, E. S.; Pistillo, C.; Popov, B.; Posiadala-Zezula, M.; Poutissou, J.-M.; Pritchard, A.; Przewlocki, P.; Quilain, B.; Radermacher, T.; Radicioni, E.; Ratoff, P. N.; Rayner, M. A.; Reinherz-Aronis, E.; Riccio, C.; Rondio, E.; Rossi, B.; Roth, S.; Ruggeri, A. C.; Rychter, A.; Sakashita, K.; Sánchez, F.; Scantamburlo, E.; Scholberg, K.; Schwehr, J.; Scott, M.; Seiya, Y.; Sekiguchi, T.; Sekiya, H.; Sgalaberna, D.; Shah, R.; Shaikhiev, A.; Shaker, F.; Shaw, D.; Shiozawa, M.; Shirahige, T.; Smy, M.; Sobczyk, J. T.; Sobel, H.; Steinmann, J.; Stewart, T.; Stowell, P.; Suda, Y.; Suvorov, S.; Suzuki, A.; Suzuki, S. Y.; Suzuki, Y.; Tacik, R.; Tada, M.; Takeda, A.; Takeuchi, Y.; Tamura, R.; Tanaka, H. K.; Tanaka, H. A.; Thakore, T.; Thompson, L. F.; Tobayama, S.; Toki, W.; Tomura, T.; Tsukamoto, T.; Tzanov, M.; Vagins, M.; Vallari, Z.; Vasseur, G.; Vilela, C.; Vladisavljevic, T.; Wachala, T.; Walter, C. W.; Wark, D.; Wascko, M. O.; Weber, A.; Wendell, R.; Wilking, M. J.; Wilkinson, C.; Wilson, J. R.; Wilson, R. J.; Wret, C.; Yamada, Y.; Yamamoto, K.; Yanagisawa, C.; Yano, T.; Yen, S.; Yershov, N.; Yokoyama, M.; Yuan, T.; Yu, M.; Zalewska, A.; Zalipska, J.; Zambelli, L.; Zaremba, K.; Ziembicki, M.; Zimmerman, E. D.; Zito, M.; T2K Collaboration

2018-01-01

This paper reports the first differential measurement of the charged-current interaction cross section of νμ on water with no pions in the final state. This flux-averaged measurement has been made using the T2K experiment's off-axis near detector, and is reported in doubly differential bins of muon momentum and angle. The flux-averaged total cross section in a restricted region of phase space was found to be σ =(0.95 ±0.08 (stat) ±0.06 (det syst)±0.04 (model syst)±0.08 (flux ))×10-38 cm2/n .

Decomposition of total solvation energy into core, side-chains and water contributions: Role of cross correlations and protein conformational fluctuations in dynamics of hydration layer

NASA Astrophysics Data System (ADS)

Mondal, Sayantan; Mukherjee, Saumyak; Bagchi, Biman

2017-09-01

Dynamical coupling between water and amino acid side-chain residues in solvation dynamics is investigated by selecting residues often used as natural probes, namely tryptophan, tyrosine and histidine, located at different positions on protein surface. Such differently placed residues are found to exhibit different timescales of relaxation. The total solvation response measured by the probe is decomposed in terms of its interactions with (i) protein core, (ii) side-chain and (iii) water. Significant anti cross-correlation among these contributions are observed. When the motion of the protein side-chains is quenched, solvation either becomes faster or slower depending on the location of the probe.

Charge transfer and ionization in collisions of Si3+ with H from low to high energy

NASA Astrophysics Data System (ADS)

Wang, J. G.; He, B.; Ning, Y.; Liu, C. L.; Yan, J.; Stancil, P. C.; Schultz, D. R.

2006-11-01

Charge transfer processes due to collisions of ground state Si3+(3sS1) ions with atomic hydrogen are investigated using the quantum-mechanical molecular-orbital close-coupling (MOCC) and classical-trajectory Monte Carlo (CTMC) methods. The MOCC calculations utilize ab initio adiabatic potentials and nonadiabatic radial coupling matrix elements obtained from Herrero [J. Phys. B 29, 5583 (1996)] which were calculated with a full configuration-interaction method. Total and state-selective single-electron capture cross sections are obtained for collision energies from 0.01eV/u to 1MeV/u . Total and state-selective rate coefficients are also presented for temperatures from 2×103K to 107K . Comparison with existing data reveals that the total CTMC cross sections are in good agreement with the experimental measurements at the higher considered energies and that previous Landau-Zener calculations underestimate the total rate coefficients by a factor of up to two. The CTMC calculations of target ionization are presented for high energies.

Nuclear medium effects in muonic neutrino interactions with energies from 0.2 to 1.5 GeV

NASA Astrophysics Data System (ADS)

Vargas, D.; Samana, A. R.; Velasco, F. G.; Hoyos, O. R.; Guzmán, F.; Bernal-Castillo, J. L.; Andrade-II, E.; Perez, R.; Deppman, A.; Barbero, C. A.; Mariano, A. E.

2017-11-01

Nuclear reactions induced by muon neutrinos with energies from 0.2 to 1.5 GeV in the Monte Carlo calculation framework in the intranuclear cascade model are studied. This study was done by comparing the available experimental data and theoretical values of total cross section, and the energy distribution of emitted lepton energy in the reaction muon neutrino nucleus, using the targets 12C, 16O, 27Al, 40Ar, 56Fe, and 208Pb. A phenomenological model of primary neutrino-nucleon interaction gives good agreement between our theoretical inclusive neutrino nucleus cross section and the available experimental data. Some interesting results on the behavior of the cross section as function of 1 p -1 n and higher contributions are also sketched. The previous results on the fraction of fake events in available experiments in 12C were expanded for the set of studied nuclei. With the increase of mass targets, the nuclear effects in the cross sections were observed and the importance of taking into account fake events in the reactions was noted.

ν{sub μ} CCπ° reaction in the tracker of the ND280 detector in the T2K experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Batkiewicz, Marcela

A good knowledge of both inclusive and exclusive neutrino interaction cross sections is one of the key issues for a precise determination of the neutrino oscillation parameters in the T2K experiment. These studies are performed at the near detector (ND280). Its central tracker part equipped with a water target is used, among others, to study the ν{sub μ}CCπ° reaction. At the energies of the T2K neutrino beam its contribution to the total cross section is relatively large, so the reaction is a potential source of the background for the quasi-elastic ν{sub μ}CC reaction. Two different production mechanisms contribute to ν{submore » μ}CCπ°: single pion resonance production and Deep Inelastic Scattering (DIS). In addition, Final State Interactions (FSI) have to be considered. Thus, the analysis of the ν{sub μ}CCπ° reaction aims also at a better tuning of the Monte Carlo (MC) models used to describe neutrino interactions in T2K. This paper describes selection criteria leading to the determination of the inclusive and exclusive cross sections for the π° production in the ν{sub μ}CC interactions.« less

Photon interaction study of organic nonlinear optical materials in the energy range 122-1330 keV

NASA Astrophysics Data System (ADS)

Awasarmol, Vishal V.; Gaikwad, Dhammajyot K.; Raut, Siddheshwar D.; Pawar, Pravina P.

2017-01-01

In the present study, the mass attenuation coefficient (μm) of six organic nonlinear optical materials has been calculated in the energy range 122-1330 keV and compared with the obtained values from the WinXCOM program. It is found that there is a good agreement between theoretical and experimental values (<3%). The linear attenuation coefficients (μ) total atomic cross section (σt, a), and total electronic cross section (σt, el) have also been calculated from the obtained μm values and their variations with photon energy have been plotted. From the present work, it is observed that the variation of obtained values of μm, μ, σt, a, and σt, el strongly depends on the photon energy and decreases or increases due to chemical composition and density of the sample. All the samples have been studied extensively using transmission method with a view to utilize the material for radiation dosimetry. Investigated samples are good material for radiation dosimetry due their low effective atomic number. The mass attenuation coefficient (μm), linear attenuation coefficients (μ), total atomic cross section (σt, a), total electronic cross section (σt, el), effective atomic numbers (Zeff), molar extinction coefficient (ε), mass energy absorption coefficient (μen/ρ) and effective atomic energy absorption cross section (σa, en) of all sample materials have been carried out and transmission curves have been plotted. The transmission curve shows that the variation of all sample materials decreases with increasing photon energy.

Pseudostate methods and differential cross sections for antiproton ionization of atomic hydrogen and helium

DOE Office of Scientific and Technical Information (OSTI.GOV)

McGovern, M.; Walters, H. R. J.; Assafrao, D.

2010-03-15

A relaxed form of a recent impact parameter coupled pseudostate approximation of McGovern et al. [Phys. Rev. A 79, 042707 (2009)] for calculating differential ionization cross sections is proposed. This greatly eases the computational burden in cases where a range of ejected electron energies has to be considered. The relaxed approximation is tested against exact first Born calculations for antiproton impact on H and nonperturbatively for the highly nonperturbative system of Au{sup 53+} incident upon He. The approximation performs well in these tests. It is shown how, with a little further approximation, the relaxed theory leads to a widely usedmore » prescription for the total ionization cross section. Results for differential ionization of H and He by antiprotons are presented. These reveal the growing dominance of the interaction between the antiproton and the target nucleus at low impact energies and show the changing importance of the role of the postcollisional interaction between the antiproton and the ejected electron.« less

Cross sections for electron scattering by carbon disulfide in the low- and intermediate-energy range

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brescansin, L. M.; Iga, I.; Lee, M.-T.

2010-01-15

In this work, we report a theoretical study on e{sup -}-CS{sub 2} collisions in the low- and intermediate-energy ranges. Elastic differential, integral, and momentum-transfer cross sections, as well as grand total (elastic + inelastic) and absorption cross sections, are reported in the 1-1000 eV range. A recently proposed complex optical potential composed of static, exchange, and correlation-polarization plus absorption contributions is used to describe the electron-molecule interaction. The Schwinger variational iterative method combined with the distorted-wave approximation is applied to calculate the scattering amplitudes. The comparison between our calculated results and the existing experimental and/or theoretical results is encouraging.

Measurement of Neutrino and Antineutrino Total Charged-Current Cross Sections on Carbon with MINERvA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ren, Lu

This thesis presents a measurement of charged-current inclusive cross sections of muon neutrino and antineutrino interaction on carbon, and antineutrino to neutrino cross section ratio, r, in the energy range 2 - 22 GeV, with data collected in the MINERA experiment. The dataset corresponds to an exposure of 3.2 x 10 20 protons on target (POT) for neutrinos and 1.01020 POT for antineutrinos. Measurement of neutrino and antineutrino charged-current inclusive cross sections provides essential constraints for future long baseline neutrino oscillation experiment at a few GeV energy range. Our measured antineutrino cross section has an uncertainty in the range 6.1%more » - 10.5% and is the most precise measurement below 6 GeV to date. The measured r has an uncertainty of 5.0% - 7.5%. This is the rst measurement below 6 GeV since Gargamelle in 1970s. The cross sections are measured as a function of neutrino energy by dividing the eciency corrected charged-current sample with extracted uxes. Fluxes are obtained using the low- method, which uses low hadronic energy subsamples of charged-current inclusive sample to extract ux. Measured cross sections show good agreement with the prediction of neutrino interaction models above 7 GeV, and are about 10% below the model below 7 GeV. The measured r agrees with the GENIE model [1] over the whole energy region. The measured cross sections and r are compared with world data.« less

Saturated fat intake modulates the association between a genetic risk score of obesity and BMI in two US populations

PubMed Central

Casas-Agustench, Patricia; Arnett, Donna K.; Smith, Caren E.; Lai, Chao-Qiang; Parnell, Laurence D.; Borecki, Ingrid B.; Frazier-Wood, Alexis C.; Allison, Matthew; Chen, Yii-Der Ida; Taylor, Kent D.; Rich, Stephen S.; Rotter, Jerome I.; Lee, Yu-Chi; Ordovás, José M.

2014-01-01

Combining multiple genetic variants related to obesity into a genetic risk score (GRS) might improve identification of individuals at risk of developing obesity. Moreover, characterizing gene-diet interactions is a research challenge to establish dietary recommendations to individuals with higher predisposition to obesity. Our objective was to analyze the association between an obesity GRS and BMI in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) population, focusing on gene-diet interactions with total fat and saturated fatty acid (SFA) intake and to replicate findings in Multi-Ethnic Study of Atherosclerosis (MESA) population. Cross-sectional analyses included 783 US Caucasian participants from GOLDN and 2035 from MESA. Dietary intakes were estimated with validated food frequency questionnaires. Height and weight were measured. A weighted GRS was calculated on the basis of 63 obesity-associated variants. Multiple linear regression models adjusted by potential confounders were used to examine gene-diet interactions between dietary intake (total fat and SFA) and the obesity GRS in determining BMI. Significant interactions were found between total fat intake and the obesity GRS using these variables as continuous for BMI (P for interaction=0.010, 0.046, and 0.002 in GOLDN, MESA and meta-analysis, respectively). These association terms were stronger when assessing interactions between SFA intake and GRS for BMI (P for interaction=0.005, 0.018, and <0.001 in GOLDN, MESA and meta-analysis, respectively). SFA intake interacts with an obesity GRS in modulating BMI in two US populations. Although to determine the causal direction requires further investigation, these findings suggest that potential dietary recommendations to reduce BMI effectively in populations with high obesity GRS would be to reduce total fat intake mainly by limiting SFAs. PMID:24794412

Potential Drug-Drug Interactions among Patients prescriptions collected from Medicine Out-patient Setting.

PubMed

Farooqui, Riffat; Hoor, Talea; Karim, Nasim; Muneer, Mehtab

2018-01-01

To identify and evaluate the frequency, severity, mechanism and common pairs of drug-drug interactions (DDIs) in prescriptions by consultants in medicine outpatient department. This cross sectional descriptive study was done by Pharmacology department of Bahria University Medical & Dental College (BUMDC) in medicine outpatient department (OPD) of a private hospital in Karachi from December 2015 to January 2016. A total of 220 prescriptions written by consultants were collected. Medications given with patient's diagnosis were recorded. Drugs were analyzed for interactions by utilizing Medscape drug interaction checker, drugs.com checker and stockley`s drug interactions index. Two hundred eleven prescriptions were selected while remaining were excluded from the study because of unavailability of the prescribed drugs in the drug interaction checkers. In 211 prescriptions, two common diagnoses were diabetes mellitus (28.43%) and hypertension (27.96%). A total of 978 medications were given. Mean number of medications per prescription was 4.6. A total of 369 drug-drug interactions were identified in 211 prescriptions (175%). They were serious 4.33%, significant 66.12% and minor 29.53%. Pharmacokinetic and pharmacodynamic interactions were 37.94% and 51.21% respectively while 10.84% had unknown mechanism. Number wise common pairs of DDIs were Omeprazole-Losartan (S), Gabapentine- Acetaminophen (M), Losartan-Diclofenac (S). The frequency of DDIs is found to be too high in prescriptions of consultants from medicine OPD of a private hospital in Karachi. Significant drug-drug interactions were more and mostly caused by Pharmacodynamic mechanism. Number wise evaluation showed three common pairs of drugs involved in interactions.

Potential Drug-Drug Interactions among Patients prescriptions collected from Medicine Out-patient Setting

PubMed Central

Farooqui, Riffat; Hoor, Talea; Karim, Nasim; Muneer, Mehtab

2018-01-01

Objective: To identify and evaluate the frequency, severity, mechanism and common pairs of drug-drug interactions (DDIs) in prescriptions by consultants in medicine outpatient department. Methods: This cross sectional descriptive study was done by Pharmacology department of Bahria University Medical & Dental College (BUMDC) in medicine outpatient department (OPD) of a private hospital in Karachi from December 2015 to January 2016. A total of 220 prescriptions written by consultants were collected. Medications given with patient's diagnosis were recorded. Drugs were analyzed for interactions by utilizing Medscape drug interaction checker, drugs.com checker and stockley`s drug interactions index. Two hundred eleven prescriptions were selected while remaining were excluded from the study because of unavailability of the prescribed drugs in the drug interaction checkers. Results: In 211 prescriptions, two common diagnoses were diabetes mellitus (28.43%) and hypertension (27.96%). A total of 978 medications were given. Mean number of medications per prescription was 4.6. A total of 369 drug-drug interactions were identified in 211 prescriptions (175%). They were serious 4.33%, significant 66.12% and minor 29.53%. Pharmacokinetic and pharmacodynamic interactions were 37.94% and 51.21% respectively while 10.84% had unknown mechanism. Number wise common pairs of DDIs were Omeprazole-Losartan (S), Gabapentine- Acetaminophen (M), Losartan-Diclofenac (S). Conclusion: The frequency of DDIs is found to be too high in prescriptions of consultants from medicine OPD of a private hospital in Karachi. Significant drug-drug interactions were more and mostly caused by Pharmacodynamic mechanism. Number wise evaluation showed three common pairs of drugs involved in interactions. PMID:29643896

Calculation of absorption parameters for selected narcotic drugs in the energy range from 1 keV to 100 GeV

NASA Astrophysics Data System (ADS)

Akman, Ferdi; Kaçal, Mustafa Recep; Akdemir, Fatma; Araz, Aslı; Turhan, Mehmet Fatih; Durak, Rıdvan

2017-04-01

The total mass attenuation coefficients (μ/ρ), total molecular (σt,m), atomic (σt,a) and electronic (σt,e) cross sections, effective atomic numbers (Zeff) and electron density (NE) were computed in the wide energy region from 1 keV to 100 GeV for the selected narcotic drugs such as morphine, heroin, cocaine, ecstasy and cannabis. The changes of μ/ρ, σt,m, σt,a, σt,e, Zeff and NE with photon energy for total photon interaction shows the dominance of different interaction process in different energy regions. The variations of μ/ρ, σt,m, σt,a, σt,e, Zeff and NE depend on the atom number, photon energy and chemical composition of narcotic drugs. Also, these parameters change with number of elements, the range of atomic numbers in narcotic drugs and total molecular weight. These data can be useful in the field of forensic sciences and medical diagnostic.

Electron capture and excitation processes in H+-H collisions in dense quantum plasmas

NASA Astrophysics Data System (ADS)

Jakimovski, D.; Markovska, N.; Janev, R. K.

2016-10-01

Electron capture and excitation processes in proton-hydrogen atom collisions taking place in dense quantum plasmas are studied by employing the two-centre atomic orbital close-coupling (TC-AOCC) method. The Debye-Hückel cosine (DHC) potential is used to describe the plasma screening effects on the Coulomb interaction between charged particles. The properties of a hydrogen atom with DHC potential are investigated as a function of the screening strength of the potential. It is found that the decrease in binding energy of nl levels with increasing screening strength is considerably faster than in the case of the Debye-Hückel (DH) screening potential, appropriate for description of charged particle interactions in weakly coupled classical plasmas. This results in a reduction in the number of bound states in the DHC potential with respect to that in the DH potential for the same plasma screening strength, and is reflected in the dynamics of excitation and electron capture processes for the two screened potentials. The TC-AOCC cross sections for total and state-selective electron capture and excitation cross sections with the DHC potential are calculated for a number of representative screening strengths in the 1-300 keV energy range and compared with those for the DH and pure Coulomb potential. The total capture cross sections for a selected number of screening strengths are compared with the available results from classical trajectory Monte Carlo calculations.

The effect of aging on pacing strategies of cross-country skiers and the role of performance level.

PubMed

Nikolaidis, Pantelis Theodoros; Villiger, Elias; Rosemann, Thomas; Knechtle, Beat

2018-01-01

The participation of master cross-country (XC) skiers in training and competition has increased during the last decades; however, little is known yet about whether these athletes differ from their younger counterparts in aspects of performance such as pacing. Therefore, the aim of the present study was to examine the combined effect of age and performance (race time) on pacing in cross-country (XC) skiing. We analyzed all finishers ( n  = 79,722) in 'Vasaloppet' from 2012 to 2017, the largest cross-country skiing race in the world, classified according to their race time into 10 groups: 3-4 h, 4-5 h, ..., 12-13 h. A trivial main effect of sex on total pace range was observed ( p  < 0.001, η 2  = 0.002), where women (44.1 ± 10.2%) had larger total pace range than men (40.9 ± 11.8%). A large main effect of performance group on total pace range was shown ( p  < 0.001, η 2  = 0.160), where the smallest total pace range was 21.8 ± 1.9% (3-4 h group) and the largest 50.1 ± 9.9% (10-11 h group). A trivial sex×performance group interaction on total pace range was found ( p  < 0.001, η 2  = 0.001) with the largest sex difference in pacing shown in 9-10 h group. A trivial and small main effect of age was found in women ( p  < 0.001, η 2  = 0.005) and men ( p  < 0.001, η 2  = 0.011), respectively, where the masters had smaller total pace range than their younger counterparts. A trivial age group×performance group interaction on total pace range was observed in both women ( p  < 0.001, η 2  = 0.008) and men ( p  < 0.001, η 2  = 0.006) with smaller differences among age groups in the faster performance groups. In summary, master XC skiers adopted a relatively even pacing independently from their race time and the differences in pacing from the younger XC skiers were more pronounced in the slower masters. These findings suggest that exercise attenuates the decline of performance in master XC skiers as shown by the similar pacing strategies between fast master XC skiers and their younger counterparts.

Electromagnetic Dissociation Cross Sections using Weisskopf-Ewing Theory

NASA Technical Reports Server (NTRS)

Adamczyk, Anne M.; Norbury, John W.

2011-01-01

It is important that accurate estimates of crew exposure to radiation are obtained for future long-term space missions. Presently, several space radiation transport codes exist to predict the radiation environment, all of which take as input particle interaction cross sections that describe the nuclear interactions between the particles and the shielding material. The space radiation transport code HZETRN uses the nuclear fragmentation model NUCFRG2 to calculate Electromagnetic Dissociation (EMD) cross sections. Currently, NUCFRG2 employs energy independent branching ratios to calculate these cross sections. Using Weisskopf-Ewing (WE) theory to calculate branching ratios, however, is more advantageous than the method currently employed in NUCFRG2. The WE theory can calculate not only neutron and proton emission, as in the energy independent branching ratio formalism used in NUCFRG2, but also deuteron, triton, helion, and alpha particle emission. These particles can contribute significantly to total exposure estimates. In this work, photonuclear cross sections are calculated using WE theory and the energy independent branching ratios used in NUCFRG2 and then compared to experimental data. It is found that the WE theory gives comparable, but mainly better agreement with data than the energy independent branching ratio. Furthermore, EMD cross sections for single neutron, proton, and alpha particle removal are calculated using WE theory and an energy independent branching ratio used in NUCFRG2 and compared to experimental data.

Time-Resolved Proteomic Visualization of Dendrimer Cellular Entry and Trafficking.

PubMed

Wang, Linna; Yang, Li; Pan, Li; Kadasala, Naveen Reddy; Xue, Liang; Schuster, Robert J; Parker, Laurie L; Wei, Alexander; Tao, W Andy

2015-10-14

Our understanding of the complex cell entry pathways would greatly benefit from a comprehensive characterization of key proteins involved in this dynamic process. Here we devise a novel proteomic strategy named TITAN (Tracing Internalization and TrAfficking of Nanomaterials) to reveal real-time protein-dendrimer interactions using a systems biology approach. Dendrimers functionalized with photoreactive cross-linkers were internalized by HeLa cells and irradiated at set time intervals, then isolated and subjected to quantitative proteomics. In total, 809 interacting proteins cross-linked with dendrimers were determined by TITAN in a detailed temporal manner during dendrimer internalization, traceable to at least two major endocytic mechanisms, clathrin-mediated and caveolar/raft-mediated endocytosis. The direct involvement of the two pathways was further established by the inhibitory effect of dynasore on dendrimer uptake and changes in temporal profiles of key proteins.

Measurements of cross-section of charge current inclusive of antineutrino scattering off nucleons using carbon, iron, lead and scintillator at MINER$$\

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rakotondravohitra, Laza

2015-08-18

Neutrino physics is one of the most active fields in the domaine of high energy physics during the last century. The need of precise measurement of neutrino-nucleus interactions required by the neutrino oscillation experiments is a an exiting step. These measurements of cross-section are more than essential for neutrino oscillation experiment. Over the year, many measurements from varieties of experiments have been presented. MINERνA is one of the world leaders in measuring cross-section of neutrino and antineutrino -nucleus interactions. MINERνA is a neutrino-nucleus scattering experiment installed in the few-GeV NuMI beam line at Fermilab. In order to study nuclear dependence,more » MINERνA is endowed with different types of solid nuclear targets as well are liquid targets such as helium and water. This thesis presents measurements of cross-section of antineutrino scattering off nucleons using a variety of solid nuclear targets, carbon, iron, lead and also polystyrene scintillator (CH). The data set of antineutrino used for this analysis was taken between March and July 2010 with a total of 1.60X10 20 protons on target. Charged current inclusive interactions were selected by requiring a positive muon and kinematics limitation of acceptance of the muon spectrometer are applied. The analysis requires neutrino energy between 2GeV et 20GeV and the angle of muon θ mu < 17degree . The absolute cross-section # as function of neutrino energy and the differential cross-section dσ/ dx bj measured and shown the corresponding systematics for each nuclear targets. Data results are compared with prediction of the models implemented in the neutrino events generators GENIE 2.6.2 used by the experiment.« less

Investigation of the effects of miniscrew-assisted rapid palatal expansion on airflow in the upper airway of an adult patient with obstructive sleep apnea syndrome using computational fluid-structure interaction analysis

PubMed Central

Hur, Jae-Sik; Kim, Hyoung-Ho; Choi, Jin-Young; Suh, Sang-Ho

2017-01-01

Objective The objective of this study was to investigate the effects of miniscrew-assisted rapid palatal expansion (MARPE) on changes in airflow in the upper airway (UA) of an adult patient with obstructive sleep apnea syndrome (OSAS) using computational fluid-structure interaction analysis. Methods Three-dimensional UA models fabricated from cone beam computed tomography images obtained before (T0) and after (T1) MARPE in an adult patient with OSAS were used for computational fluid dynamics with fluid-structure interaction analysis. Seven and nine cross-sectional planes (interplane distance of 10 mm) in the nasal cavity (NC) and pharynx, respectively, were set along UA. Changes in the cross-sectional area and changes in airflow velocity and pressure, node displacement, and total resistance at maximum inspiration (MI), rest, and maximum expiration (ME) were investigated at each plane after MARPE. Results The cross-sectional areas at most planes in NC and the upper half of the pharynx were significantly increased at T1. Moreover, airflow velocity decreased in the anterior NC at MI and ME and in the nasopharynx and oropharynx at MI. The decrease in velocity was greater in NC than in the pharynx. The airflow pressure in the anterior NC and entire pharynx exhibited a decrease at T1. The amount of node displacement in NC and the pharynx was insignificant at both T0 and T1. Absolute values for the total resistance at MI, rest, and ME were lower at T1 than at T0. Conclusions MARPE improves airflow and decreases resistance in UA; therefore, it may be an effective treatment modality for adult patients with moderate OSAS. PMID:29090123

Serum bicarbonate and bone mineral density in US adults.

PubMed

Chen, Wei; Melamed, Michal L; Abramowitz, Matthew K

2015-02-01

Chronic metabolic acidosis leads to bone mineral loss and results in lower bone mineral density (BMD), which is a risk factor for osteoporosis-related fractures. The effect of low-level metabolic acidosis on bone density in the general population is unknown. Cross-sectional study. 9,724 nationally representative adults 20 years or older in NHANES (National Health and Nutrition Examination Survey) 1999-2004. Serum bicarbonate level. Lumbar and total BMD, as well as low lumbar and total bone mass, defined as 1.0 SD below the sex-specific mean value of young adults. BMD was measured by dual-energy x-ray absorptiometry and serum bicarbonate was measured in all participants. Both men and women with lower serum bicarbonate levels were more likely to be current smokers and had higher body mass index and estimated net endogenous acid production. There was a significant linear trend across quartiles of serum bicarbonate with lumbar BMD in the total population, as well as in sex-specific models (P=0.02 for all 3 models, P=0.1 for interaction). For total BMD, a significant association was seen with serum bicarbonate level for women but not men (P=0.02 and P=0.1, respectively; P=0.8 for interaction), and a significant association was seen for postmenopausal women but not premenopausal women (P=0.02 and P=0.2, respectively; P=0.5 for interaction). Compared with women with serum bicarbonate levels <24mEq/L, those with serum bicarbonate levels ≥27mEq/L had 0.018-g/cm(2) higher total BMD (95% CI, 0.004-0.032; P=0.01) and 31% lower odds of having low total bone mass (OR, 0.68; 95% CI, 0.46-0.99; P=0.049). Cross-sectional study using a single measurement of serum bicarbonate. Subgroup differences are not definitive. Lower serum bicarbonate levels are associated with lower BMD in US adults. Further studies should examine whether serum bicarbonate levels should be incorporated into the diagnostic assessment and management of osteoporosis. Copyright © 2015 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

Serum Bicarbonate and Bone Mineral Density in US Adults

PubMed Central

Chen, Wei; Melamed, Michal L.; Abramowitz, Matthew K.

2014-01-01

Background Chronic metabolic acidosis leads to bone mineral loss and results in lower bone mineral density (BMD), which is a risk factor for osteoporosis-related fractures. The effect of low-level metabolic acidosis on bone density in the general population is unknown. Study Design Cross-sectional study. Setting & Participants 9,724 nationally representative adults aged 20 years or older in the National Health and Nutrition Examination Survey 1999-2004. Factor Serum bicarbonate level. Outcomes Lumbar and total BMD as well as low lumbar and total bone mass defined as 1.0 SD below sex-specific mean of young adults. Measurements BMD was measured by dual-energy X-ray absorptiometry and serum bicarbonate levels were measured in all participants. Results Both men and women with lower serum bicarbonate levels were more likely to be current smokers and had higher body mass index and estimated net endogenous acid production. There was a significant linear trend across quartiles of serum bicarbonate with lumbar BMD among the total population as well as in sex-specific models (p=0.02 for all three models, p=0.1 for interaction). For total BMD, a significant association was seen with serum bicarbonate levels among women but not men (p=0.02 and p=0.1, respectively; p=0.8 for interaction); and a significant association was seen among post-menopausal women but not pre-menopausal women (p=0.02 and p=0.2, respectively; p=0.5 for interaction). Compared to women with serum bicarbonate level <24 mEq/L, those with serum bicarbonate ≥27 mEq/L had 0.018 g/cm2 higher total BMD (95% CI, 0.004-0.032; p=0.01) and had 31% lower odds of having low total bone mass (OR, 0.68; 95% CI, 0.46-0.99; p=0.05). Limitations Cross-sectional study using a single measurement of serum bicarbonate level. The subgroup differences are not definitive. Conclusions Lower serum bicarbonate levels are associated with lower BMD in US adults. Further studies should examine whether serum bicarbonate levels should be incorporated into the diagnostic assessment and management of osteoporosis. PMID:25168294

Power corrections to the universal heavy WIMP-nucleon cross section

NASA Astrophysics Data System (ADS)

Chen, Chien-Yi; Hill, Richard J.; Solon, Mikhail P.; Wijangco, Alexander M.

2018-06-01

WIMP-nucleon scattering is analyzed at order 1 / M in Heavy WIMP Effective Theory. The 1 / M power corrections, where M ≫mW is the WIMP mass, distinguish between different underlying UV models with the same universal limit and their impact on direct detection rates can be enhanced relative to naive expectations due to generic amplitude-level cancellations at leading order. The necessary one- and two-loop matching calculations onto the low-energy effective theory for WIMP interactions with Standard Model quarks and gluons are performed for the case of an electroweak SU(2) triplet WIMP, considering both the cases of elementary fermions and composite scalars. The low-velocity WIMP-nucleon scattering cross section is evaluated and compared with current experimental limits and projected future sensitivities. Our results provide the most robust prediction for electroweak triplet Majorana fermion dark matter direct detection rates; for this case, a cancellation between two sources of power corrections yields a small total 1 / M correction, and a total cross section close to the universal limit for M ≳ few × 100GeV. For the SU(2) composite scalar, the 1 / M corrections introduce dependence on underlying strong dynamics. Using a leading chiral logarithm evaluation, the total 1 / M correction has a larger magnitude and uncertainty than in the fermionic case, with a sign that further suppresses the total cross section. These examples provide definite targets for future direct detection experiments and motivate large scale detectors capable of probing to the neutrino floor in the TeV mass regime.

Gene-environment interaction study for BMI reveals interactions between genetic factors and physical activity, alcohol consumption and socioeconomic status

PubMed Central

Karlsson, Torgny; Ek, Weronica E.

2017-01-01

Previous genome-wide association studies (GWAS) have identified hundreds of genetic loci to be associated with body mass index (BMI) and risk of obesity. Genetic effects can differ between individuals depending on lifestyle or environmental factors due to gene-environment interactions. In this study, we examine gene-environment interactions in 362,496 unrelated participants with Caucasian ancestry from the UK Biobank resource. A total of 94 BMI-associated SNPs, selected from a previous GWAS on BMI, were used to construct weighted genetic scores for BMI (GSBMI). Linear regression modeling was used to estimate the effect of gene-environment interactions on BMI for 131 lifestyle factors related to: dietary habits, smoking and alcohol consumption, physical activity, socioeconomic status, mental health, sleeping patterns, as well as female-specific factors such as menopause and childbirth. In total, 15 lifestyle factors were observed to interact with GSBMI, of which alcohol intake frequency, usual walking pace, and Townsend deprivation index, a measure of socioeconomic status, were all highly significant (p = 1.45*10−29, p = 3.83*10−26, p = 4.66*10−11, respectively). Interestingly, the frequency of alcohol consumption, rather than the total weekly amount resulted in a significant interaction. The FTO locus was the strongest single locus interacting with any of the lifestyle factors. However, 13 significant interactions were also observed after omitting the FTO locus from the genetic score. Our analyses indicate that many lifestyle factors modify the genetic effects on BMI with some groups of individuals having more than double the effect of the genetic score. However, the underlying causal mechanisms of gene-environmental interactions are difficult to deduce from cross-sectional data alone and controlled experiments are required to fully characterise the causal factors. PMID:28873402

Interactions between psychosocial and built environment factors in explaining older adults' physical activity.

PubMed

Carlson, Jordan A; Sallis, James F; Conway, Terry L; Saelens, Brian E; Frank, Lawrence D; Kerr, Jacqueline; Cain, Kelli L; King, Abby C

2012-01-01

To evaluate ecological model predictions of cross-level interactions among psychosocial and environmental correlates of physical activity in 719 community-dwelling older adults in the Baltimore, Maryland and Seattle, Washington areas during 2005-2008. Walkability, access to parks and recreation facilities and moderate-to-vigorous physical activity (MVPA) minutes per week (min/week) were measured objectively. Neighborhood aesthetics, walking facilities, social support, self-efficacy, barriers and transportation and leisure walking min/week were self-reported. Walkability interacted with social support in explaining total MVPA (B=13.71) and with social support (B=7.90), self-efficacy (B=7.66) and barriers (B=-8.26) in explaining walking for transportation. Aesthetics interacted with barriers in explaining total MVPA (B=-12.20) and walking facilities interacted with self-efficacy in explaining walking for leisure (B=-10.88; Ps<.05). Summarizing across the interactions, living in a supportive environment (vs. unsupportive) was related to 30-59 more min/week of physical activity for participants with more positive psychosocial attributes, but only 0-28 more min/week for participants with less positive psychosocial attributes. Results supported synergistic interactions between built environment and psychosocial factors in explaining physical activity among older adults. Findings suggest multilevel interventions may be most effective in increasing physical activity. Copyright © 2011 Elsevier Inc. All rights reserved.

Interaction in Balanced Cross Nested Designs

NASA Astrophysics Data System (ADS)

Ramos, Paulo; Mexia, João T.; Carvalho, Francisco; Covas, Ricardo

2011-09-01

Commutative Jordan Algebras, CJA, are used in the study of mixed models obtained, through crossing and nesting, from simpler ones. In the study of cross nested models the interaction between nested factors have been systematically discarded. However this can constitutes an artificial simplification of the models. We point out that, when two crossed factors interact, such interaction is symmetric, both factors playing in it equivalent roles, while when two nested factors interact, the interaction is determined by the nesting factor. These interactions will be called interactions with nesting. In this work we present a coherent formulation of the algebraic structure of models enabling the choice of families of interactions between cross and nested factors using binary operations on CJA.

Measurement of double-differential muon neutrino charged-current interactions on C8 H8 without pions in the final state using the T2K off-axis beam

NASA Astrophysics Data System (ADS)

Abe, K.; Andreopoulos, C.; Antonova, M.; Aoki, S.; Ariga, A.; Assylbekov, S.; Autiero, D.; Barbi, M.; Barker, G. J.; Barr, G.; Bartet-Friburg, P.; Batkiewicz, M.; Berardi, V.; Berkman, S.; Bhadra, S.; Blondel, A.; Bolognesi, S.; Bordoni, S.; Boyd, S. B.; Brailsford, D.; Bravar, A.; Bronner, C.; Buizza Avanzini, M.; Calland, R. G.; Cao, S.; Caravaca Rodríguez, J.; Cartwright, S. L.; Castillo, R.; Catanesi, M. G.; Cervera, A.; Cherdack, D.; Chikuma, N.; Christodoulou, G.; Clifton, A.; Coleman, J.; Collazuol, G.; Cremonesi, L.; Dabrowska, A.; De Rosa, G.; Dealtry, T.; Denner, P. F.; Dennis, S. R.; Densham, C.; Dewhurst, D.; Di Lodovico, F.; Di Luise, S.; Dolan, S.; Drapier, O.; Duffy, K. E.; Dumarchez, J.; Dytman, S.; Dziewiecki, M.; Emery-Schrenk, S.; Ereditato, A.; Feusels, T.; Finch, A. J.; Fiorentini, G. A.; Friend, M.; Fujii, Y.; Fukuda, D.; Fukuda, Y.; Furmanski, A. P.; Galymov, V.; Garcia, A.; Giffin, S. G.; Giganti, C.; Gizzarelli, F.; Gonin, M.; Grant, N.; Hadley, D. R.; Haegel, L.; Haigh, M. D.; Hamilton, P.; Hansen, D.; Hara, T.; Hartz, M.; Hasegawa, T.; Hastings, N. C.; Hayashino, T.; Hayato, Y.; Helmer, R. L.; Hierholzer, M.; Hillairet, A.; Himmel, A.; Hiraki, T.; Hirota, S.; Hogan, M.; Holeczek, J.; Horikawa, S.; Hosomi, F.; Huang, K.; Ichikawa, A. K.; Ieki, K.; Ikeda, M.; Imber, J.; Insler, J.; Intonti, R. A.; Irvine, T. J.; Ishida, T.; Ishii, T.; Iwai, E.; Iwamoto, K.; Izmaylov, A.; Jacob, A.; Jamieson, B.; Jiang, M.; Johnson, S.; Jo, J. H.; Jonsson, P.; Jung, C. K.; Kabirnezhad, M.; Kaboth, A. C.; Kajita, T.; Kakuno, H.; Kameda, J.; Karlen, D.; Karpikov, I.; Katori, T.; Kearns, E.; Khabibullin, M.; Khotjantsev, A.; Kielczewska, D.; Kikawa, T.; Kim, H.; Kim, J.; King, S.; Kisiel, J.; Knight, A.; Knox, A.; Kobayashi, T.; Koch, L.; Koga, T.; Konaka, A.; Kondo, K.; Kopylov, A.; Kormos, L. L.; Korzenev, A.; Koshio, Y.; Kropp, W.; Kudenko, Y.; Kurjata, R.; Kutter, T.; Lagoda, J.; Lamont, I.; Larkin, E.; Lasorak, P.; Laveder, M.; Lawe, M.; Lazos, M.; Lindner, T.; Liptak, Z. J.; Litchfield, R. P.; Li, X.; Longhin, A.; Lopez, J. P.; Ludovici, L.; Lu, X.; Magaletti, L.; Mahn, K.; Malek, M.; Manly, S.; Marino, A. D.; Marteau, J.; Martin, J. F.; Martins, P.; Martynenko, S.; Maruyama, T.; Matveev, V.; Mavrokoridis, K.; Ma, W. Y.; Mazzucato, E.; McCarthy, M.; McCauley, N.; McFarland, K. S.; McGrew, C.; Mefodiev, A.; Mezzetto, M.; Mijakowski, P.; Minamino, A.; Mineev, O.; Mine, S.; Missert, A.; Miura, M.; Moriyama, S.; Mueller, Th. A.; Murphy, S.; Myslik, J.; Nakadaira, T.; Nakahata, M.; Nakamura, K. G.; Nakamura, K.; Nakamura, K. D.; Nakayama, S.; Nakaya, T.; Nakayoshi, K.; Nantais, C.; Nielsen, C.; Nirkko, M.; Nishikawa, K.; Nishimura, Y.; Nowak, J.; O'Keeffe, H. M.; Ohta, R.; Okumura, K.; Okusawa, T.; Oryszczak, W.; Oser, S. M.; Ovsyannikova, T.; Owen, R. A.; Oyama, Y.; Palladino, V.; Palomino, J. L.; Paolone, V.; Patel, N. D.; Pavin, M.; Payne, D.; Perkin, J. D.; Petrov, Y.; Pickard, L.; Pickering, L.; Pinzon Guerra, E. S.; Pistillo, C.; Popov, B.; Posiadala-Zezula, M.; Poutissou, J.-M.; Poutissou, R.; Przewlocki, P.; Quilain, B.; Radicioni, E.; Ratoff, P. N.; Ravonel, M.; Rayner, M. A. M.; Redij, A.; Reinherz-Aronis, E.; Riccio, C.; Rojas, P.; Rondio, E.; Roth, S.; Rubbia, A.; Rychter, A.; Sacco, R.; Sakashita, K.; Sánchez, F.; Sato, F.; Scantamburlo, E.; Scholberg, K.; Schoppmann, S.; Schwehr, J.; Scott, M.; Seiya, Y.; Sekiguchi, T.; Sekiya, H.; Sgalaberna, D.; Shah, R.; Shaikhiev, A.; Shaker, F.; Shaw, D.; Shiozawa, M.; Shirahige, T.; Short, S.; Smy, M.; Sobczyk, J. T.; Sorel, M.; Southwell, L.; Stamoulis, P.; Steinmann, J.; Stewart, T.; Suda, Y.; Suvorov, S.; Suzuki, A.; Suzuki, K.; Suzuki, S. Y.; Suzuki, Y.; Tacik, R.; Tada, M.; Takahashi, S.; Takeda, A.; Takeuchi, Y.; Tanaka, H. K.; Tanaka, H. A.; Terhorst, D.; Terri, R.; Thakore, T.; Thompson, L. F.; Tobayama, S.; Toki, W.; Tomura, T.; Touramanis, C.; Tsukamoto, T.; Tzanov, M.; Uchida, Y.; Vacheret, A.; Vagins, M.; Vallari, Z.; Vasseur, G.; Wachala, T.; Wakamatsu, K.; Walter, C. W.; Wark, D.; Warzycha, W.; Wascko, M. O.; Weber, A.; Wendell, R.; Wilkes, R. J.; Wilking, M. J.; Wilkinson, C.; Wilson, J. R.; Wilson, R. J.; Yamada, Y.; Yamamoto, K.; Yamamoto, M.; Yanagisawa, C.; Yano, T.; Yen, S.; Yershov, N.; Yokoyama, M.; Yoshida, K.; Yuan, T.; Yu, M.; Zalewska, A.; Zalipska, J.; Zambelli, L.; Zaremba, K.; Ziembicki, M.; Zimmerman, E. D.; Zito, M.; Żmuda, J.; T2K Collaboration

2016-06-01

We report the measurement of muon neutrino charged-current interactions on carbon without pions in the final state at the T2K beam energy using 5.734 ×1020 protons on target. For the first time the measurement is reported as a flux-integrated, double-differential cross section in muon kinematic variables (cos θμ, pμ), without correcting for events where a pion is produced and then absorbed by final state interactions. Two analyses are performed with different selections, background evaluations and cross-section extraction methods to demonstrate the robustness of the results against biases due to model-dependent assumptions. The measurements compare favorably with recent models which include nucleon-nucleon correlations but, given the present precision, the measurement does not distinguish among the available models. The data also agree with Monte Carlo simulations which use effective parameters that are tuned to external data to describe the nuclear effects. The total cross section in the full phase space is σ =(0.417 ±0.047 (syst ) ±0.005 (stat ) )×10-38 cm2 nucleon-1 and the cross section integrated in the region of phase space with largest efficiency and best signal-over-background ratio (cos θμ>0.6 and pμ>200 MeV ) is σ =(0.202 ±0.036 (syst ) ±0.003 (stat ) )×10-38 cm2 nucleon-1 .

Prediction of Physical Activity Level Using Processes of Change From the Transtheoretical Model: Experiential, Behavioral, or an Interaction Effect?

PubMed

Romain, Ahmed Jérôme; Horwath, Caroline; Bernard, Paquito

2018-01-01

The purpose of the present study was to compare prediction of physical activity (PA) by experiential or behavioral processes of change (POCs) or an interaction between both types of processes. A cross-sectional study. This study was conducted using an online questionnaire. A total of 394 participants (244 women, 150 men), with a mean age of 35.12 ± 12.04 years and a mean body mass index of 22.97 ± 4.25 kg/m 2 were included. Participants completed the Processes of Change, Stages of Change questionnaires, and the International Physical Activity Questionnaire to evaluate self-reported PA level (total, vigorous, and moderate PA). Hierarchical multiple regression models were used to test the prediction of PA level. For both total PA (β = .261; P < .001) and vigorous PA (β = .297; P < .001), only behavioral POCs were a significant predictor. Regarding moderate PA, only the interaction between experiential and behavioral POCs was a significant predictor (β = .123; P = .017). Our results provide confirmation that behavioral processes are most prominent in PA behavior. Nevertheless, it is of interest to note that the interaction between experiential and behavioral POCs was the only element predicting moderate PA level. Experiential processes were not associated with PA level.

Topological, total, and elastic cross sections for K/sup +/p,. pi. /sup +/p, and pp interactions at 147 GeV/c

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brick, D.; Rudnicka, H.; Shapiro, A.M.

1982-06-01

The Fermilab hybrid 30-in. bubble-chamber spectrometer was exposed to a tagged 147-GeV/c positive beam containing ..pi../sup +/, K/sup +/, and p. A sample of 3003 K/sup +/p, 19 410 pp, and 20 745 ..pi../sup +/p interactions is used to derive sigma/sub n/, , f/sub 2//sup tsc/c, and /D for each beam particle. These values are compared to values obtained at other, mostly lower, beam momenta. The overall dependence of on E/sub a/, the available center-of-mass energy, for these three reactions as well as ..pi../sup -/p and pp interactions has been determined.

Genetic control of soybean seed oil: I. QTL and genes associated with seed oil concentration in RIL populations derived from crossing moderately high-oil parents.

PubMed

Eskandari, Mehrzad; Cober, Elroy R; Rajcan, Istvan

2013-02-01

Soybean seed is a major source of oil for human consumption worldwide and the main renewable feedstock for biodiesel production in North America. Increasing seed oil concentration in soybean [Glycine max (L.) Merrill] with no or minimal impact on protein concentration could be accelerated by exploiting quantitative trait loci (QTL) or gene-specific markers. Oil concentration in soybean is a polygenic trait regulated by many genes with mostly small effects and which is negatively associated with protein concentration. The objectives of this study were to discover and validate oil QTL in two recombinant inbred line (RIL) populations derived from crosses between three moderately high-oil soybean cultivars, OAC Wallace, OAC Glencoe, and RCAT Angora. The RIL populations were grown across several environments over 2 years in Ontario, Canada. In a population of 203 F(3:6) RILs from a cross of OAC Wallace and OAC Glencoe, a total of 11 genomic regions on nine different chromosomes were identified as associated with oil concentration using multiple QTL mapping and single-factor ANOVA. The percentage of the phenotypic variation accounted for by each QTL ranged from 4 to 11 %. Of the five QTL that were tested in a population of 211 F(3:5) RILs from the cross RCAT Angora × OAC Wallace, a "trait-based" bidirectional selective genotyping analysis validated four QTL (80 %). In addition, a total of seven two-way epistatic interactions were identified for oil concentration in this study. The QTL and epistatic interactions identified in this study could be used in marker-assisted introgression aimed at pyramiding high-oil alleles in soybean cultivars to increase oil concentration for biodiesel as well as edible oil applications.

Protein interaction networks from literature mining

NASA Astrophysics Data System (ADS)

Ihara, Sigeo

2005-03-01

The ability to accurately predict and understand physiological changes in the biological network system in response to disease or drug therapeutics is of crucial importance in life science. The extensive amount of gene expression data generated from even a single microarray experiment often proves difficult to fully interpret and comprehend the biological significance. An increasing knowledge of protein interactions stored in the PubMed database, as well as the advancement of natural language processing, however, makes it possible to construct protein interaction networks from the gene expression information that are essential for understanding the biological meaning. From the in house literature mining system we have developed, the protein interaction network for humans was constructed. By analysis based on the graph-theoretical characterization of the total interaction network in literature, we found that the network is scale-free and semantic long-ranged interactions (i.e. inhibit, induce) between proteins dominate in the total interaction network, reducing the degree exponent. Interaction networks generated based on scientific text in which the interaction event is ambiguously described result in disconnected networks. In contrast interaction networks based on text in which the interaction events are clearly stated result in strongly connected networks. The results of protein-protein interaction networks obtained in real applications from microarray experiments are discussed: For example, comparisons of the gene expression data indicative of either a good or a poor prognosis for acute lymphoblastic leukemia with MLL rearrangements, using our system, showed newly discovered signaling cross-talk.

Multifield stochastic particle production: beyond a maximum entropy ansatz

DOE Office of Scientific and Technical Information (OSTI.GOV)

Amin, Mustafa A.; Garcia, Marcos A.G.; Xie, Hong-Yi

2017-09-01

We explore non-adiabatic particle production for N {sub f} coupled scalar fields in a time-dependent background with stochastically varying effective masses, cross-couplings and intervals between interactions. Under the assumption of weak scattering per interaction, we provide a framework for calculating the typical particle production rates after a large number of interactions. After setting up the framework, for analytic tractability, we consider interactions (effective masses and cross couplings) characterized by series of Dirac-delta functions in time with amplitudes and locations drawn from different distributions. Without assuming that the fields are statistically equivalent, we present closed form results (up to quadratures) formore » the asymptotic particle production rates for the N {sub f}=1 and N {sub f}=2 cases. We also present results for the general N {sub f} >2 case, but with more restrictive assumptions. We find agreement between our analytic results and direct numerical calculations of the total occupation number of the produced particles, with departures that can be explained in terms of violation of our assumptions. We elucidate the precise connection between the maximum entropy ansatz (MEA) used in Amin and Baumann (2015) and the underlying statistical distribution of the self and cross couplings. We provide and justify a simple to use (MEA-inspired) expression for the particle production rate, which agrees with our more detailed treatment when the parameters characterizing the effective mass and cross-couplings between fields are all comparable to each other. However, deviations are seen when some parameters differ significantly from others. We show that such deviations become negligible for a broad range of parameters when N {sub f}>> 1.« less

Alcohol use and mental health in adolescents: interactions with age and gender-findings from the Dutch 2001 Health Behaviour in School-Aged Children survey.

PubMed

Verdurmen, Jacqueline; Monshouwer, Karin; van Dorsselaer, Saskia; ter Bogt, Tom; Vollebergh, Wilma

2005-09-01

This study examines the association between alcohol use and mental health in adolescence, specifically the interaction with age and gender. Data were derived from the 2001 Health Behaviour in School-Aged Children (HBSC) survey--a repeated cross-sectional study with a total of 5,730 students aged 12-16 years, carried out as part of the World Health Organization cross-national HBSC Project. A two-stage random sampling procedure was used. Written questionnaires were administered in classroom settings. These contained questions about alcohol and other drug use as well as sociodemographic and behavioral variables. In addition, the Youth Self-Report was used to assess mental health. Weekly alcohol use among adolescents is related to less withdrawn behavior and more delinquent, aggressive behavior. Significant interactions between weekly alcohol use and age were found on both externalizing and internalizing problems, indicating a stronger association between weekly alcohol use and problems among younger adolescents. No interactions with gender were found. Particularly at a young age, the weekly use of alcohol is associated with mental health problems. Regular alcohol use should alert parents and professionals that these adolescents might experience problems in other areas.

Radiation doses and neutron irridation effects on human cells based on calculations

NASA Astrophysics Data System (ADS)

Radojevic, B. B.; Cukavac, M.; Jovanovic, D.

In general, main aim of our paper is to follow influence of neutron's radiation on materials, but one of possible applications of fast neutrons in therapeutical reasons i.e. their influence on carcinom cells of difficuilt geometries in human bodies too. Interactions between neutrons and human cells of tissue are analysed here. We know that the light nuclei of hydrogen, nitrogen, carbon, and oxygen are main constituents of human cells, and that different nuclear models are usually used to present interactions of nuclear particles with mentioned elements. Some of most widely used pre-equilibrium nuclear models are: intranuclear cascade model (ICN), Harp-Miller-Berne (HMB), geometry-dependent hybrid (GDH) and exciton models (EM). In this paper is studied and calculated the primary energetic spectra of the secundary particles (neutrons, protons, and gamas) emitted from this interactions, and followed by corresponding integral cross sections, based on exciton model (EM). The total emission cross-section is the sum of emissions in all stages of energies. Obtained spectra for interactions type of (n, n'), (n, p), and (n, ?), for various incident neutron energies in the interval from 3 MeV up to 30 MeV are analysed too. Some results of calculations are presented here.

The LArIAT Experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nutini, Irene

2017-09-20

A short overview of the Liquid Argon In A Testbeam (LArIAT) experiment hosted at Fermilab is reported. This program supports the Liquid Argon Time Projection Chamber (LArTPC) Neutrino Experiments at Fermilab. The LArIAT program consists of a calibration of a LArTPC in a dedicated charged particle beamline. The first total pion interaction cross section measurement ever made on argon is presented here (preliminary result).

Full Ionisation In Binary-Binary Encounters With Small Positive Energies

NASA Astrophysics Data System (ADS)

Sweatman, W. L.

2006-08-01

Interactions between binary stars and single stars and binary stars and other binary stars play a key role in the dynamics of a dense stellar system. Energy can be transferred between the internal dynamics of a binary and the larger scale dynamics of the interacting objects. Binaries can be destroyed and created by the interaction. In a binary-binary encounter, full ionisation occurs when both of the binary stars are destroyed in the interaction to create four single stars. This is only possible when the total energy of the system is positive. For very small energies the probability of this occurring is very low and it tends towards zero as the total energy tends towards zero. Here the case is considered for which all the stars have equal masses. An asymptotic power law is predicted relating the probability of full ionisation with the total energy when this latter quantity is small. The exponent, which is approximately 2.31, is compared with the results from numerical scattering experiments. The theoretical approach taken is similar to one used previously in the three-body problem. It makes use of the fact that the most dramatic changes in scale and energies of a few-body system occur when its components pass near to a central configuration. The position, and number, of these configurations is not known for the general four-body problem, however, with equal masses there are known to be exactly five different cases. Separate consideration and comparison of the properties of orbits close to each of these five central configurations enables the prediction of the form of the cross-section for full ionisation for the case of small positive total energy. This is the relation between total energy and the probability of total ionisation described above.

Low-Energy Electron Interactions with CF_4

NASA Astrophysics Data System (ADS)

Christophorou, Loucas G.; Olthoff, James K.; Rao, M. V. V. S.

1996-10-01

Carbon tetrafluoride is one of the most widely used components of feed gas mixtures employed for a variety of plasma assisted materials processing applications. In this presentation, we synthesize and assess the available information on the cross sections and rate coefficients of collisional interations of CF4 with electrons.(L. G. Christophorou, J. K. Olthoff, and M.V. V. S. Rao, J. Phys. Chem. Ref. Data, submitted (May 1996)) A ``recommended'' data set is presented, based upon available data for: (i) cross sections for electron scattering (total, elastic, momentum, differential, inelastic), electron impact ionization (total and partial), electron impact dissociation, and electron attachment; and (ii) coefficients for electron transport, electron attachment, and electron impact ionization. -Research sponsored in part by the U.S. Air Force Wright Laboratory under contract F33615-96-C-2600 with the University of Tennessee. Also, Department of Physics, The University of Tennessee, Knoxville, TN.

ηc production in photon-induced interactions at the LHC

NASA Astrophysics Data System (ADS)

Gonçalves, V. P.; Moreira, B. D.

2018-05-01

In this paper we investigate the ηc production by photon-photon and photon-hadron interactions in p p and p A collisions at the LHC energies. The inclusive and diffractive contributions for the ηc photoproduction are estimated using the nonrelativistic quantum chromodynamics (NRQCD) formalism. We estimate the rapidity and transverse momentum distributions for the ηc photoproduction in hadronic collisions at the LHC and present our estimate for the total cross sections at the Run 2 energies. A comparison with the predictions for the exclusive ηc photoproduction, which is a direct probe of the odderon, is also presented.

Multinucleon pion absorption on {sup 4}He into the pppn final state

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lehmann, A.; Backenstoss, G.; Koehler, J.

1997-10-01

Results from a 4{pi} solid angle measurement of the reaction {pi}{sup +4}He{r_arrow}pppn at incident pion energies of T{sub {pi}{sup +}}= 70, 118, 162, 239, and 330 MeV are presented. Integrated cross sections are given for the reactions where three nucleons participate, leading to energetic (ppp) or (ppn) final states, and for states where four nucleons are involved (pppn). The two three-nucleon absorption modes were investigated in particular, and an energy dependent isospin ratio of the cross sections of {sigma}{sub ppn}/ {sigma}{sub ppp}=3.6{plus_minus}1.3, 2.6 {plus_minus}0.5, 1.8{plus_minus}0.3, 1.4{plus_minus} 0.2, and 1.8{plus_minus}0.6 was determined from 70 to 330 MeV. The differential cross sectionsmore » were described by a complete set of eight independent variables and compared to simple cascade and phase space models. From this analysis the contributions from initial state interactions to the multinucleon absorption cross sections were found to be more important at higher pion energies, while those from final state interactions are stronger at lower energies. However, both mechanisms combined were found to account for not more than one-third of the total pppn multinucleon yield. The remaining strength is reasonably well reproduced by phase space models, but shows a dependence on the incident pion{close_quote}s orbital angular momentum. The isospin structure of the (ppp) and (ppn) final states is not understood, nor are some structures in their distributions. The four-nucleon yield (pppn) was found to be weak (1{endash}8{percent} of the total absorption cross section) and shows no evidence for a {open_quotes}double- {Delta}{close_quotes} excitation. {copyright} {ital 1997} {ital The American Physical Society}« less

Fusion cross sections measurements with MUSIC

NASA Astrophysics Data System (ADS)

Carnelli, P. F. F.; Fernández Niello, J. O.; Almaraz-Calderon, S.; Rehm, K. E.; Albers, M.; Digiovine, B.; Esbensen, H.; Henderson, D.; Jiang, C. L.; Nusair, O.; Palchan-Hazan, T.; Pardo, R. C.; Ugalde, C.; Paul, M.; Alcorta, M.; Bertone, P. F.; Lai, J.; Marley, S. T.

2014-09-01

The interaction between exotic nuclei plays an important role for understanding the reaction mechanism of the fusion processes as well as for the energy production in stars. With the advent of radioactive beams new frontiers for fusion reaction studies have become accessible. We have performed the first measurements of the total fusion cross sections in the systems 10 , 14 , 15C + 12C using a newly developed active target-detector system (MUSIC). Comparison of the obtained cross sections with theoretical predictions show a good agreement in the energy region accessible with existing radioactive beams. This type of comparison allows us to calibrate the calculations for cases that cannot be studied in the laboratory with the current experimental capabilities. The high efficiency of this active detector system will allow future measurements with even more neutron-rich isotopes. The interaction between exotic nuclei plays an important role for understanding the reaction mechanism of the fusion processes as well as for the energy production in stars. With the advent of radioactive beams new frontiers for fusion reaction studies have become accessible. We have performed the first measurements of the total fusion cross sections in the systems 10 , 14 , 15C + 12C using a newly developed active target-detector system (MUSIC). Comparison of the obtained cross sections with theoretical predictions show a good agreement in the energy region accessible with existing radioactive beams. This type of comparison allows us to calibrate the calculations for cases that cannot be studied in the laboratory with the current experimental capabilities. The high efficiency of this active detector system will allow future measurements with even more neutron-rich isotopes. This work is supported by the U.S. DOE Office of Nuclear Physics under Contract No. DE-AC02-06CH11357 and the Universidad Nacional de San Martin, Argentina, Grant SJ10/39.

Optical potentials for nuclear level structures and nucleon interactions data of tin isotopes based on the soft-rotator model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Jeong-Yeon; Hahn, Insik; Kim, Yeongduk

2009-06-15

The soft-rotator model is applied to self-consistent analyses of the nuclear level structures and the nucleon interaction data of the even-even Sn isotopes, {sup 116}Sn, {sup 118}Sn, {sup 120}Sn, and {sup 122}Sn. The model successfully describes low-lying collective levels of these isotopes, which exhibit neither typical rotational nor harmonic vibrational structures. The experimental nucleon interaction data--total neutron cross sections, proton reaction cross sections, and nucleon elastic and inelastic scattering data--are well described up to 200 MeV in a coupled-channels optical model approach. For the calculations, nuclear wave functions for the Sn isotopes are taken from the nonaxial soft-rotator model withmore » the model parameters adjusted to fit the measured low-lying collective level structures. We find that the {beta}{sub 2} and {beta}{sub 3} deformations for incident protons are larger than those for incident neutrons by {approx}15%, which is clear evidence of the deviation from the pure collective model for these isotopes.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, C.; Albergo, S.; Caccia, Z.

A liquid hydrogen target was used to study the nuclear fragmentation of beams of relativistic heavy ions, [sup 22]Ne to [sup 58]Ni, over an energy range 400 to 900 MeV/nucleon. The experiments were carried out at the Lawrence Berkeley Laboratory Bevalac HISS facility, using the charge-velocity-rigidity method to identify the charged fragments. Here we describe the general concept of the experiment and present total charge-changing cross sections obtained from 17 separate runs. These new measured cross sections display an energy dependence which follows semiempirical model predictions. The mass dependence of the cross sections behaves as predicted by optical models, butmore » within the experimental energy range, the optical model parameters display a clear energy dependence. The isospin of the projectile nuclei also appears to be an important factor in the interaction process.« less

Saturated fat intake modulates the association between an obesity genetic risk score and body mass index in two US populations.

PubMed

Casas-Agustench, Patricia; Arnett, Donna K; Smith, Caren E; Lai, Chao-Qiang; Parnell, Laurence D; Borecki, Ingrid B; Frazier-Wood, Alexis C; Allison, Matthew; Chen, Yii-Der Ida; Taylor, Kent D; Rich, Stephen S; Rotter, Jerome I; Lee, Yu-Chi; Ordovás, José M

2014-12-01

Combining multiple genetic variants related to obesity into a genetic risk score (GRS) might improve identification of individuals at risk of developing obesity. Moreover, characterizing gene-diet interactions is a research challenge to establish dietary recommendations to individuals with higher predisposition to obesity. Our objective was to analyze the association between an obesity GRS and body mass index (BMI) in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) population, focusing on gene-diet interactions with total fat and saturated fatty acid (SFA) intake, and to replicate findings in the Multi-Ethnic Study of Atherosclerosis (MESA) population. Cross-sectional analyses included 783 white US participants from GOLDN and 2,035 from MESA. Dietary intakes were estimated with validated food frequency questionnaires. Height and weight were measured. A weighted GRS was calculated on the basis of 63 obesity-associated variants. Multiple linear regression models adjusted by potential confounders were used to examine gene-diet interactions between dietary intake (total fat and SFA) and the obesity GRS in determining BMI. Significant interactions were found between total fat intake and the obesity GRS using these variables as continuous for BMI (P for interaction=0.010, 0.046, and 0.002 in GOLDN, MESA, and meta-analysis, respectively). These association terms were stronger when assessing interactions between SFA intake and GRS for BMI (P for interaction=0.005, 0.018, and <0.001 in GOLDN, MESA, and meta-analysis, respectively). SFA intake interacts with an obesity GRS in modulating BMI in two US populations. Although determining the causal direction requires further investigation, these findings suggest that potential dietary recommendations to reduce BMI effectively in populations with high obesity GRS would be to reduce total fat intake mainly by limiting SFAs. Copyright © 2014 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

Closing Report for NASA Cooperative Agreement NASA-1-242

NASA Technical Reports Server (NTRS)

Maung, Khin Maung

1999-01-01

Reliable estimates of exposures due to ionizing radiations are of paramount importance in achieving human exploration and development of space, and in several technologically important and scientifically significant areas impacting on industrial and public health. For proper assessment of radiation exposures reliable transport codes are needed. An essential input to the transport codes is the information about the interaction of ions and neutrons with the matter. Most of the information about this interaction is put in by nuclear cross section data. In order to obtain an accurate parameterization of cross sections data, theoretical input is indispensable especially for the processes where there is little or no experimental data available. In the grant period reliable data base was developed and a phenomenological model was developed for the total absorption cross sections valid for any charged/uncharged light, medium and heavy collision pairs valid for the entire energy range. It is gratifying to note the success of the model. The cross sections model has been adopted and is in use in NASA cosmic ray detector development projects, the radiation protection and shielding programs and several DoE laboratories and institutions. A list of the publications based on the work done during the grant period is given below and a sample copy of one of the papers is enclosed with this report.

Cross-reactivity of antibodies with phenolic compounds in pistachios during quantification of ochratoxin A by commercial enzyme-linked immunosorbent assay kits.

PubMed

Lee, Hyun Jung; Meldrum, Alexander D; Rivera, Nicholas; Ryu, Dojin

2014-10-01

Ochratoxin A (OTA), a nephrotoxic mycotoxin, naturally occurs in wide range of agricultural commodities. Typical screening of OTA involves various enzyme-linked immunosorbent assay (ELISA) methods. Pistachio (Pistacia vera L.) is a rich source of phenolic compounds that may result in a false positive due to structural similarities to OTA. The present study investigated the cross-reactivity profiles of phenolic compounds using two commercial ELISA test kits. High-performance liquid chromatography was used to confirm the concentration of OTA in the pistachio samples and compared with the results obtained from ELISA. When the degree of interaction and 50 % inhibitory concentration of phenolic compounds were determined, the cross-reactivity showed a pattern similar to that observed with the commercial ELSIA kits, although quantitatively different. In addition, the degree of interaction increased with the increasing concentration of phenolic compounds. The ELISA value had stronger correlations with the content of total phenolic compound, gallic acid, and catechin (R(2) = 0.757, 0.732, and 0.729, respectively) compared with epicatechin (R(2) = 0.590). These results suggest that phenolic compounds in pistachio skins may cross-react with the OTA antibody and lead to a false positive or to an overestimation of OTA concentration in ELISA-based tests.

Experimental and theoretical electron-scattering cross-section data for dichloromethane

NASA Astrophysics Data System (ADS)

Krupa, K.; Lange, E.; Blanco, F.; Barbosa, A. S.; Pastega, D. F.; Sanchez, S. d'A.; Bettega, M. H. F.; García, G.; Limão-Vieira, P.; Ferreira da Silva, F.

2018-04-01

We report on a combination of experimental and theoretical investigations into the elastic differential cross sections (DCSs) and integral cross sections for electron interactions with dichloromethane, C H2C l2 , in the incident electron energy over the 7.0-30 eV range. Elastic electron-scattering cross-section calculations have been performed within the framework of the Schwinger multichannel method implemented with pseudopotentials (SMCPP), and the independent-atom model with screening-corrected additivity rule including interference-effects correction (IAM-SCAR+I). The present elastic DCSs have been found to agree reasonably well with the results of IAM-SCAR+I calculations above 20 eV and also with the SMC calculations below 30 eV. Although some discrepancies were found for 7 eV, the agreement between the two theoretical methodologies is remarkable as the electron-impact energy increases. Calculated elastic DCSs are also reported up to 10000 eV for scattering angles from 0° to 180° together with total cross section within the IAM-SCAR+I framework.

Onset of Asymptotic Scaling in Deuteron Photodisintegration

NASA Astrophysics Data System (ADS)

Rossi, P.; Mirazita, M.; Ronchetti, F.; de Sanctis, E.; Adams, G.; Ambrozewicz, P.; Anciant, E.; Anghinolfi, M.; Asavapibhop, B.; Audit, G.; Avakian, H.; Bagdasaryan, H.; Ball, J. P.; Barrow, S.; Battaglieri, M.; Beard, K.; Bektasoglu, M.; Bellis, M.; Benmouna, N.; Berman, B. L.; Bertozzi, W.; Bianchi, N.; Biselli, A. S.; Boiarinov, S.; Bonner, B. E.; Bouchigny, S.; Bradford, R.; Branford, D.; Briscoe, W. J.; Brooks, W. K.; Burkert, V. D.; Butuceanu, C.; Calarco, J. R.; Carman, D. S.; Carnahan, B.; Chen, S.; Cole, P. L.; Cords, D.; Corvisiero, P.; Crabb, D.; Crannell, H.; Cummings, J. P.; de Vita, R.; Degtyarenko, P. V.; Denizli, H.; Dennis, L.; Deppman, A.; Dharmawardane, K. V.; Dhuga, K. S.; Djalali, C.; Dodge, G. E.; Doughty, D.; Dragovitsch, P.; Dugger, M.; Dytman, S.; Dzyubak, O. P.; Egiyan, H.; Egiyan, K. S.; Elouadrhiri, L.; Empl, A.; Eugenio, P.; Fatemi, R.; Feuerbach, R. J.; Ficenec, J.; Forest, T. A.; Funsten, H.; Gai, M.; Gavalian, G.; Gilad, S.; Gilfoyle, G. P.; Giovanetti, K. L.; Gordon, C. I.; Griffioen, K.; Guidal, M.; Guillo, M.; Guo, L.; Gyurjyan, V.; Hadjidakis, C.; Hakobyan, R. S.; Hardie, J.; Heddle, D.; Hersman, F. W.; Hicks, K.; Hicks, R. S.; Holtrop, M.; Hu, J.; Hyde-Wright, C. E.; Ilieva, Y.; Ito, M. M.; Jenkins, D.; Jo, H. S.; Joo, K.; Kellie, J. D.; Khandaker, M.; Kim, K. Y.; Kim, K.; Kim, W.; Klein, A.; Klein, F. J.; Klimenko, A. V.; Klusman, M.; Kossov, M.; Kramer, L. H.; Kuhn, J.; Kuhn, S. E.; Lachniet, J.; Laget, J. M.; Lawrence, D.; Li, Ji; Lima, A. C.; Livingston, K.; Lukashin, K.; Manak, J. J.; Marchand, C.; McAleer, S.; McCarthy, J.; McNabb, J. W.; Mecking, B. A.; Mehrabyan, S.; Melone, J. J.; Mestayer, M. D.; Meyer, C. A.; Mikhailov, K.; Miskimen, R.; Mokeev, V.; Morand, L.; Morrow, S. A.; Muccifora, V.; Mueller, J.; Mutchler, G. S.; Napolitano, J.; Nasseripour, R.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Niczyporuk, B. B.; Niyazov, R. A.; Nozar, M.; O'Brien, J. T.; O'Rielly, G. V.; Osipenko, M.; Ostrovidov, A.; Park, K.; Pasyuk, E.; Peterson, G.; Philips, S. A.; Pivnyuk, N.; Pocanic, D.; Pogorelko, O.; Polli, E.; Pozdniakov, S.; Preedom, B. M.; Price, J. W.; Prok, Y.; Protopopescu, D.; Qin, L. M.; Raue, B. A.; Riccardi, G.; Ricco, G.; Ripani, M.; Ritchie, B. G.; Rosner, G.; Rowntree, D.; Rubin, P. D.; Sabatié, F.; Salgado, C.; Santoro, J. P.; Sapunenko, V.; Schumacher, R. A.; Serov, V. S.; Sharabian, Y. G.; Shaw, J.; Simionatto, S.; Skabelin, A. V.; Smith, E. S.; Smith, L. C.; Sober, D. I.; Spraker, M.; Stavinsky, A.; Stepanyan, S.; Stokes, B.; Stoler, P.; Strakovsky, I. I.; Strauch, S.; Taiuti, M.; Taylor, S.; Tedeschi, D. J.; Thoma, U.; Thompson, R.; Tkabladze, A.; Todor, L.; Tur, C.; Ungaro, M.; Vineyard, M. F.; Vlassov, A. V.; Wang, K.; Weinstein, L. B.; Weller, H.; Weygand, D. P.; Whisnant, C. S.; Wolin, E.; Wood, M. H.; Yegneswaran, A.; Yun, J.; Zhang, B.; Zhou, Z.

2005-01-01

We investigate the transition from the nucleon-meson to the quark-gluon description of the strong interaction using the photon energy dependence of the d(γ,p)n differential cross section for photon energies above 0.5GeV and center-of-mass proton angles between 30° and 150°. A possible signature for this transition is the onset of cross-section s-11 scaling with the total energy squared, s, at some proton transverse momentum PT. The results show that the scaling has been reached for proton transverse momentum above about 1.1 GeV/c. This may indicate that the quark-gluon regime is reached above this momentum.

Nonlinear cascades in two-dimensional turbulent magnetoconvection.

PubMed

Skandera, Dan; Müller, Wolf-Christian

2009-06-05

The dynamics of spectral transport in two-dimensional turbulent convection of electrically conducting fluids is studied by means of direct numerical simulations in the frame of the magnetohydrodynamic Boussinesq approximation. The system performs quasioscillations between two different regimes of small-scale turbulence: one dominated by nonlinear magnetohydrodynamic interactions; the other governed by buoyancy forces. The self-excited change of turbulent states is reported here for the first time. The process is controlled by the ideal invariant cross helicity, H;{C}=integral_{S}dSv.b. The observations are explained by the interplay of convective driving with the nonlinear spectral transfer of total magnetohydrodynamic energy and cross helicity.

QCD-motivated description of very high energy particle interactions

NASA Technical Reports Server (NTRS)

Gaisser, T. K.; Halzen, F.

1985-01-01

Cross sections for the production of secondaries with large transverse momentum can become comparable to the total cross section in the TeV energy range. It is argued that the onset of this effect is observed at sub TeV energies via an increase of the rapidity distribution near y = 0, an increase of p sub T with energy and, most directly, via a correlation between p sub T and multiplicity. If indeed scaling violations are associated with the hard scattering of partons, then scaling violations are largely confined to the central region and have little effect on cosmic ray data which are sensitive to the forward fragmentation region.

"Outta my way!" Individual and environmental correlates of interactions between pedestrians and vehicles during street crossings.

PubMed

Cloutier, Marie-Soleil; Lachapelle, Ugo; d'Amours-Ouellet, Andrée-Anne; Bergeron, Jacques; Lord, Sébastien; Torres, Juan

2017-07-01

Because pedestrian crash rates remain lower than other collision types, surrogate measures such as traffic interactions are now used in road safety research to complement crash history. Using naturalistic data collection, we sought to assess 1) the likelihood of occurrence of interactions between pedestrians and vehicles based on individual and crossing characteristics; and 2) differences in interaction characteristics between children, adult and senior pedestrians. Observations of pedestrian crossing behaviours (n=4687) were recorded at 278 crossings. For recorded interactions (n=843), information was collected to characterize the behaviours of involved parties. A mixed-effect logit regression model was performed to assess the factors associated with interactions. Chi-square tests evaluated differences between age groups and characteristics of observed interactions. Older adults were those more likely to be involved in an interaction event. Bicycle paths, different crossing surface material and one-way streets were significantly associated with fewer interactions with vehicles, while parked vehicles nearby and crossings on arterial roads were significantly associated with more interactions. Children and the elderly (80 years of age or more) did have distinct patterns of interaction, with more careful drivers/cyclists behaviours being observed towards children and lesser regulation compliance towards the elderly. Given the growing emphasis and adoption of active transportation in many cities, the number of interactions between pedestrians and vehicles during street crossings is likely to increase. Educating drivers and pedestrians to respect each other's space requires an understanding of where, between whom, and under what circumstances interactions occur. Such an approach can also help identify which engineering and enforcement programs are needed to ensure safe pedestrian crossings since interactions can be good markers of uncomfortable crossing situations that may deter walking and lead to more collisions. Copyright © 2017 Elsevier Ltd. All rights reserved.

Measurement of total cross sections for neutrino and antineutrino charged-current interactions in hydrogen and neon

NASA Astrophysics Data System (ADS)

Aderholz, M.; Corrigan, G.; Hoffmann, E.; Jones, G. T.; Jones, R. W. L.; Kennedy, B. W.; Miller, D. B.; Mobayyen, M. M.; Morrison, D. R. O.; Myatt, G.; Radojicic, D.; Schmid, P.; Schmitz, N.; Shotton, P. N.; Towers, S. J.; Wittek, W.; Barnham, K. W. J.; Baton, J. P.; Berggren, M.; Bertrand, D.; Bullock, F. W.; Calicchio, M.; Clayton, E. F.; Coghen, T.; Cooper-Sarkar, A. M.; Erriquez, O.; Fitch, P. J.; Fogli-Muciaccia, M. T.; Guy, J. G.; Hamisi, F.; Hulth, P. O.; Kasper, P.; Klein, H.; Lagraa, M.; Marage, P.; Middleton, R. P.; O'Neale, S. W.; Parker, M. A.; Sacton, J.; Sansum, R. A.; Simopoulou, E.; Vallée, C.; Varvell, K.; Vayaki, A.; Venus, W.; Wachmuth, H.; Wells, J.

1986-06-01

BEBC filled in turn with hydrogen, and with a neon-hydrogen mixture, was exposed to the CERN SPS wide band neutrino and antineutrino beams. The ratios of the charged-current cross sections per nucleon, σ(νH2)/σ(νNe) and σ(νH2)/σ(νNe), between 20 and 300 GeV were found to be 0.656 +/- 0.020 and 1.425 +/- 0.052, respectively. Multiplying these ratios by the revised cross sections in neon, σ(νNe)/E = (0.723 +/- 0.038) × 10-38 cm2/GeV per nucleon and σ(νNe)/E = (0.351 +/- 0.019) × 10-38 cm2/GeV per nucleon, and their ratio, σ(νNe)/σ(νNe) = 0.485 +/- 0.020,, yields values for the total charged-current cross sections on protons, σ(νp)/E and σ(νp)/E, of (0.474 +/- 0.029) × 10-38 cm2/GeV and (0.500 +/- 0.032) × 10-38 cm2/GeV. respectively, and a value for the ratio σ(νp)/σ(νp) of 1.053 +/- 0.066. Present address: University of Glasgow, Glasgow G12 8QQ, UK.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Chien-Yi; Hill, Richard J.; Solon, Mikhail P.

WIMP-nucleon scattering is analyzed at ordermore » $1/M$ in Heavy WIMP Effective Theory. The $1/M$ power corrections, where $$M\\gg m_W$$ is the WIMP mass, distinguish between different underlying UV models with the same universal limit and their impact on direct detection rates can be enhanced relative to naive expectations due to generic amplitude-level cancellations at leading order. The necessary one- and two-loop matching calculations onto the low-energy effective theory for WIMP interactions with Standard Model quarks and gluons are performed for the case of an electroweak SU(2) triplet WIMP, considering both the cases of elementary fermions and composite scalars. The low-velocity WIMP-nucleon scattering cross section is evaluated and compared with current experimental limits and projected future sensitivities. Our results provide the most robust prediction for electroweak triplet Majorana fermion dark matter direct detection rates; for this case, a cancellation between two sources of power corrections yields a small total $1/M$ correction, and a total cross section close to the universal limit for $$M \\gtrsim {\\rm few} \\times 100\\,{\\rm GeV}$$. For the SU(2) composite scalar, the $1/M$ corrections introduce dependence on underlying strong dynamics. Using a leading chiral logarithm evaluation, the total $1/M$ correction has a larger magnitude and uncertainty than in the fermionic case, with a sign that further suppresses the total cross section. These examples provide definite targets for future direct detection experiments and motivate large scale detectors capable of probing to the neutrino floor in the TeV mass regime.« less

Perturbative calculation of two-photon double electron ionization of helium

NASA Astrophysics Data System (ADS)

Ivanov, I. A.; Kheifets, A. S.

2008-05-01

We report the total integrated cross-section (TICS) of two-photon double ionization of helium in the photon energy range from 40 to 54 eV. We compute the TICS in the lowest order perturbation theory (LOPT) using the length and Kramers-Henneberger gauges of the electromagnetic interaction. Our findings indicate that the LOPT gives results for the TICS in agreement with our earlier non-perturbative calculations.

Segregation distortion and genome-wide digenic interactions affect transmission of introgressed chromatin from wild cotton species.

PubMed

Chandnani, Rahul; Wang, Baohua; Draye, Xavier; Rainville, Lisa K; Auckland, Susan; Zhuang, Zhimin; Lubbers, Edward L; May, O Lloyd; Chee, Peng W; Paterson, Andrew H

2017-10-01

This study reports transmission genetics of chromosomal segments into Gossypium hirsutum from its most distant euploid relative, Gossypium mustelinum . Mutilocus interactions and structural rearrangements affect introgression and segregation of donor chromatin. Wild allotetraploid relatives of cotton are a rich source of genetic diversity that can be used in genetic improvement, but linkage drag and non-Mendelian transmission genetics are prevalent in interspecific crosses. These problems necessitate knowledge of transmission patterns of chromatin from wild donor species in cultivated recipient species. From an interspecific cross, Gossypium hirsutum × Gossypium mustelinum, we studied G. mustelinum (the most distant tetraploid relative of Upland cotton) allele retention in 35 BC 3 F 1 plants and segregation patterns in BC 3 F 2 populations totaling 3202 individuals, using 216 DNA marker loci. The average retention of donor alleles across BC 3 F 1 plants was higher than expected and the average frequency of G. mustelinum alleles in BC 3 F 2 segregating families was less than expected. Despite surprisingly high retention of G. mustelinum alleles in BC 3 F 1 , 46 genomic regions showed no introgression. Regions on chromosomes 3 and 15 lacking introgression were closely associated with possible small inversions previously reported. Nonlinear two-locus interactions are abundant among loci with single-locus segregation distortion, and among loci originating from one of the two subgenomes. Comparison of the present results with those of prior studies indicates different permeability of Upland cotton for donor chromatin from different allotetraploid relatives. Different contributions of subgenomes to two-locus interactions suggest different fates of subgenomes in the evolution of allotetraploid cottons. Transmission genetics of G. hirsutum × G. mustelinum crosses reveals allelic interactions, constraints on fixation and selection of donor alleles, and challenges with retention of introgressed chromatin for crop improvement.

Establishment of a Photon Data Section of the BNL National Nuclear Data Center: A preliminary proposal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hanson, A.L.; Pearlstein, S.

1992-05-01

It is proposed to establish a Photon Data Section (PDS) of the BNL National Nuclear Data Center (NNDC). This would be a total program encompassing both photon-atom and photon-nucleus interactions. By utilizing the existing NNDC data base management expertise and on-line access capabilities, the implementation of photon interaction data activities within the existing NNDC nuclear structure and nuclear-reaction activities can reestablish a viable photon interaction data program at minimum cost. By taking advantage of the on-line capabilities, the x-ray users' community will have access to a dynamic, state-of-the-art data base of interaction information. The proposed information base would include datamore » that presently are scattered throughout the literature usually in tabulated form. It is expected that the data bases would include at least the most precise data available in photoelectric cross sections, atomic form factors and incoherent scattering functions, anomalous scattering factors, oscillator strengths and oscillator densities, fluorescence yields, Auger electron yields, etc. It could also include information not presently available in tabulations or in existing data bases such as EXAFS (extended x-ray absorption fine structure) reference spectra, chemical bonding induced shifts in the photoelectric absorption edge, matrix corrections, x-ray Raman, and x-ray resonant Raman cross sections. The data base will also include the best estimates of the accuracy of the interaction data as it exists in the data base. It is proposed that the PDS would support computer programs written for calculating scattering cross sections for given solid angles, sample geometries, and polarization of incident x-rays, for calculating Compton profiles, and for analyzing data as in EXAFS and x-ray fluorescence.« less

Establishment of a Photon Data Section of the BNL National Nuclear Data Center: A preliminary proposal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hanson, A.L.; Pearlstein, S.

1992-05-01

It is proposed to establish a Photon Data Section (PDS) of the BNL National Nuclear Data Center (NNDC). This would be a total program encompassing both photon-atom and photon-nucleus interactions. By utilizing the existing NNDC data base management expertise and on-line access capabilities, the implementation of photon interaction data activities within the existing NNDC nuclear structure and nuclear-reaction activities can reestablish a viable photon interaction data program at minimum cost. By taking advantage of the on-line capabilities, the x-ray users` community will have access to a dynamic, state-of-the-art data base of interaction information. The proposed information base would include datamore » that presently are scattered throughout the literature usually in tabulated form. It is expected that the data bases would include at least the most precise data available in photoelectric cross sections, atomic form factors and incoherent scattering functions, anomalous scattering factors, oscillator strengths and oscillator densities, fluorescence yields, Auger electron yields, etc. It could also include information not presently available in tabulations or in existing data bases such as EXAFS (extended x-ray absorption fine structure) reference spectra, chemical bonding induced shifts in the photoelectric absorption edge, matrix corrections, x-ray Raman, and x-ray resonant Raman cross sections. The data base will also include the best estimates of the accuracy of the interaction data as it exists in the data base. It is proposed that the PDS would support computer programs written for calculating scattering cross sections for given solid angles, sample geometries, and polarization of incident x-rays, for calculating Compton profiles, and for analyzing data as in EXAFS and x-ray fluorescence.« less

Viral coinfection is shaped by host ecology and virus-virus interactions across diverse microbial taxa and environments.

PubMed

Díaz-Muñoz, Samuel L

2017-01-01

Infection of more than one virus in a host, coinfection, is common across taxa and environments. Viral coinfection can enable genetic exchange, alter the dynamics of infections, and change the course of viral evolution. Yet, a systematic test of the factors explaining variation in viral coinfection across different taxa and environments awaits completion. Here I employ three microbial data sets of virus-host interactions covering cross-infectivity, culture coinfection, and single-cell coinfection (total: 6,564 microbial hosts, 13,103 viruses) to provide a broad, comprehensive picture of the ecological and biological factors shaping viral coinfection. I found evidence that ecology and virus-virus interactions are recurrent factors shaping coinfection patterns. Host ecology was a consistent and strong predictor of coinfection across all three data sets: cross-infectivity, culture coinfection, and single-cell coinfection. Host phylogeny or taxonomy was a less consistent predictor, being weak or absent in the cross-infectivity and single-cell coinfection models, yet it was the strongest predictor in the culture coinfection model. Virus-virus interactions strongly affected coinfection. In the largest test of superinfection exclusion to date, prophage sequences reduced culture coinfection by other prophages, with a weaker effect on extrachromosomal virus coinfection. At the single-cell level, prophage sequences eliminated coinfection. Virus-virus interactions also increased culture coinfection with ssDNA-dsDNA coinfections >2× more likely than ssDNA-only coinfections. The presence of CRISPR spacers was associated with a ∼50% reduction in single-cell coinfection in a marine bacteria, despite the absence of exact spacer matches in any active infection. Collectively, these results suggest the environment bacteria inhabit and the interactions among surrounding viruses are two factors consistently shaping viral coinfection patterns. These findings highlight the role of virus-virus interactions in coinfection with implications for phage therapy, microbiome dynamics, and viral infection treatments.

Calculation of total and ionization cross sections for electron scattering by primary benzene compounds

NASA Astrophysics Data System (ADS)

Singh, Suvam; Naghma, Rahla; Kaur, Jaspreet; Antony, Bobby

2016-07-01

The total and ionization cross sections for electron scattering by benzene, halobenzenes, toluene, aniline, and phenol are reported over a wide energy domain. The multi-scattering centre spherical complex optical potential method has been employed to find the total elastic and inelastic cross sections. The total ionization cross section is estimated from total inelastic cross section using the complex scattering potential-ionization contribution method. In the present article, the first theoretical calculations for electron impact total and ionization cross section have been performed for most of the targets having numerous practical applications. A reasonable agreement is obtained compared to existing experimental observations for all the targets reported here, especially for the total cross section.

Genetic variation and control of chloroplast pigment concentrations in Picea rubens, Picea mariana and their hybrids. I. Ambient and elevated [CO2] environments.

PubMed

Major, John E; Barsi, Debby C; Mosseler, Alex; Campbell, Moira

2007-03-01

Traits related to light-energy processing have significant ecological implications for plant fitness. We studied the effects of elevated atmospheric CO(2) concentration ([CO(2)]) on chloroplast pigment traits of a red spruce (RS) (Picea rubens Sarg.)-black spruce (BS) (P. mariana (Mill.) B.S.P.) genetic complex in two experiments: (1) a comparative species' provenance experiment from across the near-northern part of the RS range; and (2) an intra- and interspecific controlled-cross experiment. Results from the provenance experiment showed that total chlorophyll (a + b) concentration was, on average, 15% higher in ambient [CO(2)] than in elevated [CO(2)] (P < 0.001). In ambient [CO(2)], BS populations averaged 11% higher total chlorophyll and carotenoid concentrations than RS populations (P < 0.001). There were significant species, CO(2), and species x CO(2) interaction effects, with chlorophyll concentration decreasing about 7 and 26% for BS and RS, respectively, in response to elevated [CO(2)]. Results from the controlled-cross experiment showed that families with a hybrid index of 25 (25% RS) had the highest total chlorophyll concentrations, and families with hybrid indices of 75 and 100 had among the lowest amounts. Initial analysis of the controlled-cross experiment supported a more additive model of inheritance; however, parental analysis showed a significant and predominant male effect for chlorophyll concentration. In ambient and elevated [CO(2)] environments, crosses with BS males had 10.6 and 17.6% higher total chlorophyll concentrations than crosses with hybrid and RS males, respectively. Our results show that chlorophyll concentration is under strong genetic control, and that these traits are positively correlated with productivity within and across species. A significant positive correlation between chlorophyll concentration and the ratio of total plant N to root dry mass was also found (r = 0.872). The almost fourfold decrease in chlorophyll concentration in RS suggests that it would be at a competitive disadvantage compared with BS in a high [CO(2)] environment.

A Measurement of the muon neutrino charged current quasielastic interaction and a test of Lorentz violation with the MiniBooNE experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Katori, Teppei

2008-12-01

The Mini-Booster neutrino experiment (MiniBooNE) at Fermi National Accelerator Laboratory (Fermilab) is designed to search for v μ → v e appearance neutrino oscillations. Muon neutrino charged-current quasi-elastic (CCQE) interactions (v μ + n → μ + p) make up roughly 40% of our data sample, and it is used to constrain the background and cross sections for the oscillation analysis. Using high-statistics MiniBooNE CCQE data, the muon-neutrino CCQE cross section is measured. The nuclear model is tuned precisely using the MiniBooNE data. The measured total cross section is σ = (1.058 ± 0.003 (stat) ± 0.111 (syst)) x 10more » -38 cm 2 at the MiniBooNE muon neutrino beam energy (700-800 MeV). v e appearance candidate data is also used to search for Lorentz violation. Lorentz symmetry is one of the most fundamental symmetries in modern physics. Neutrino oscillations offer a new method to test it. We found that the MiniBooNE result is not well-described using Lorentz violation, however further investigation is required for a more conclusive result.« less

Social support and support groups among people with HIV/AIDS in Ghana.

PubMed

Abrefa-Gyan, Tina; Wu, Liyun; Lewis, Marilyn W

2016-01-01

HIV/AIDS, a chronic burden in Ghana, poses social and health outcome concerns to those infected. Examining the Medical Outcome Study Social Support Survey (MOS-SSS) instrument among 300 Ghanaians from a cross-sectional design, Principal Component Analysis yielded four factors (positive interaction, trust building, information giving, and essential support), which accounted for 85.73% of the total variance in the MOS-SSS. A logistic regression analysis showed that essential support was the strongest predictor of the length of time an individual stayed in the support group, whereas positive interaction indicated negative association. The study's implications for policy, research, and practice were discussed.

Search for P-ODD asymmetry in the radiative cross-section of the interaction of neutrons with lead nuclei

NASA Astrophysics Data System (ADS)

Gledenov, Yu. M.; Nesvizhevsky, V. V.; Sedyshev, P. V.; Shul'gina, E. V.; Vesna, V. A.

2014-03-01

The P-odd effect in the radiation cross section of capture of longitudinally polarized neutrons in a sample of natural lead is measured. The experiment was performed at PF1B facility at the Institut Max von Laue-Paul Langevin. The neutron polarization P n was 92%, the total flux of polarized neutrons was ˜3 × 1010 n/s, and the mean neutron wavelength was λ = 4.7 Å. Taking into account "0-test" we estimated the asymmetry: a γ(natPb) = (2.3 ± 3.5) × 10-7, i.e., α γ ≤ 8.1 × 10-7 at 90% confidence level.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singh, Suvam; Naghma, Rahla; Kaur, Jaspreet

The total and ionization cross sections for electron scattering by benzene, halobenzenes, toluene, aniline, and phenol are reported over a wide energy domain. The multi-scattering centre spherical complex optical potential method has been employed to find the total elastic and inelastic cross sections. The total ionization cross section is estimated from total inelastic cross section using the complex scattering potential-ionization contribution method. In the present article, the first theoretical calculations for electron impact total and ionization cross section have been performed for most of the targets having numerous practical applications. A reasonable agreement is obtained compared to existing experimental observationsmore » for all the targets reported here, especially for the total cross section.« less

Adaptation of Physiological and Cognitive Workload via Interactive Multi-modal Displays

DTIC Science & Technology

2014-05-28

peer-reviewed journals (N/A for none) 09/07/2013 Received Paper 8.00 James Merlo, Joseph E. Mercado , Jan B.F. Van Erp, Peter A. Hancock. Improving...08, . : , Mr. Joseph Mercado , Mr. Timothy White, Dr. Peter Hancock. Effects of Cross-Modal Sensory Cueing Automation Failurein a Target Detection Task...fields:...... ...... ...... ...... ...... PERCENT_SUPPORTEDNAME FTE Equivalent: Total Number: Discipline Joseph Mercado 0.50 Timothy White 0.50 1.00 2

A precision measurement of charm dimuon production in neutrino interactions from the NOMAD experiment

NASA Astrophysics Data System (ADS)

Samoylov, O.; Petti, R.; Alekhin, S.; Astier, P.; Autiero, D.; Baldisseri, A.; Baldo-Ceolin, M.; Banner, M.; Bassompierre, G.; Benslama, K.; Besson, N.; Bird, I.; Blumenfeld, B.; Bobisut, F.; Bouchez, J.; Boyd, S.; Bueno, A.; Bunyatov, S.; Camilleri, L.; Cardini, A.; Cattaneo, P. W.; Cavasinni, V.; Cervera-Villanueva, A.; Challis, R.; Chukanov, A.; Collazuol, G.; Conforto, G.; Conta, C.; Contalbrigo, M.; Cousins, R.; Degaudenzi, H.; De Santo, A.; Del Prete, T.; Di Lella, L.; do Couto e Silva, E.; Dumarchez, J.; Duyang, H.; Ellis, M.; Feldman, G. J.; Ferrari, R.; Ferrère, D.; Flaminio, V.; Fraternali, M.; Gaillard, J.-M.; Gangler, E.; Geiser, A.; Geppert, D.; Gibin, D.; Gninenko, S.; Godley, A.; Gomez-Cadenas, J.-J.; Gosset, J.; Gößling, C.; Gouanère, M.; Grant, A.; Graziani, G.; Guglielmi, A.; Hagner, C.; Hernando, J.; Hurst, P.; Hyett, N.; Iacopini, E.; Joseph, C.; Juget, F.; Kent, N.; Klimov, O.; Kokkonen, J.; Kovzelev, A.; Krasnoperov, A.; Kim, J. J.; Kirsanov, M.; Kulagin, S.; Kullenberg, C. T.; Lacaprara, S.; Lachaud, C.; Lakić, B.; Lanza, A.; La Rotonda, L.; Laveder, M.; Letessier-Selvon, A.; Levy, J.-M.; Libo, J.; Linssen, L.; Ljubičić, A.; Long, J.; Lupi, A.; Lyubushkin, V.; Marchionni, A.; Martelli, F.; Méchain, X.; Mendiburu, J.-P.; Meyer, J.-P.; Mezzetto, M.; Mishra, S. R.; Moorhead, G. F.; Naumov, D.; Nédélec, P.; Nefedov, Yu.; Nguyen-Mau, C.; Orestano, D.; Pastore, F.; Peak, L. S.; Pennacchio, E.; Pessard, H.; Placci, A.; Polesello, G.; Pollmann, D.; Polyarush, A.; Poulsen, C.; Popov, B.; Rebuffi, L.; Rico, J.; Riemann, P.; Roda, C.; Rubbia, A.; Salvatore, F.; Schahmaneche, K.; Schmidt, B.; Schmidt, T.; Sconza, A.; Scott, A. M.; Sevior, M.; Sillou, D.; Soler, F. J. P.; Sozzi, G.; Steele, D.; Stiegler, U.; Stipčević, M.; Stolarczyk, Th.; Tareb-Reyes, M.; Taylor, G. N.; Tereshchenko, V.; Tian, X. C.; Toropin, A.; Touchard, A.-M.; Tovey, S. N.; Tran, M.-T.; Tsesmelis, E.; Ulrichs, J.; Vacavant, L.; Valdata-Nappi, M.; Valuev, V.; Vannucci, F.; Varvell, K. E.; Veltri, M.; Vercesi, V.; Vidal-Sitjes, G.; Vieira, J.-M.; Vinogradova, T.; Weber, F. V.; Weisse, T.; Wilson, F. F.; Winton, L. J.; Wu, Q.; Yabsley, B. D.; Zaccone, H.; Zuber, K.; Zuccon, P.

2013-11-01

We present our new measurement of the cross-section for charm dimuon production in neutrino-iron interactions based upon the full statistics collected by the NOMAD experiment. After background subtraction we observe 15 344 charm dimuon events, providing the largest sample currently available. The analysis exploits the large inclusive charged current sample - about 9×106 events after all analysis cuts - and the high resolution NOMAD detector to constrain the total systematic uncertainty on the ratio of charm dimuon to inclusive Charged Current (CC) cross-sections to ˜2%. We also perform a fit to the NOMAD data to extract the charm production parameters and the strange quark sea content of the nucleon within the NLO QCD approximation. We obtain a value of mc(mc)=1.159±0.075 GeV/c2 for the running mass of the charm quark in the MS¯ scheme and a strange quark sea suppression factor of κs=0.591±0.019 at Q2=20 GeV/c2.

A study of flow past an airfoil with a jet issuing from its lower surface

NASA Technical Reports Server (NTRS)

Krothapalli, A.; Leopold, D.

1984-01-01

The aerodynamics of a NACA 0018 airfoil with a rectangular jet of finite aspect ratio exiting from its lower surface at 90 deg to the chord were investigated. The jet was located at 50% of the wing chord. Measurements include static pressures on the airfoil surface, total pressures in the near wake, and local velocity vectors in different planes of the wake. The effects of jet cross flow interaction on the aerodynamics of the airfoil are studied. It is indicated that at all values of momentum coefficients, the jet cross flow interaction produces a strong contra-rotating vortex structure in the near wake. The flow behind the jet forms a closed recirculation region which extends up to a chord length down stream of the trailing edge which results in the flow field to become highly three dimensional. The various aerodynamic force coefficients vary significantly along the span of the wing. The results are compared with a jet flap configuration.

Measurement of the Antineutrino Double-Differential Charged-Current Quasi-Elastic Scattering Cross Section at MINERvA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Patrick, Cheryl

Next-generation neutrino oscillation experiments, such as DUNE and Hyper-Kamiokande, hope to measure charge-parity (CP) violation in the lepton sector. In order to do this, they must dramatically reduce their current levels of uncertainty, particularly those due to neutrino-nucleus interaction models. As CP violation is a measure of the difference between the oscillation properties of neutrinos and antineutrinos, data about how the less-studied antineutrinos interact is especially valuable. We present the MINERvA experiment's first double-differential scattering cross sections for antineutrinos on scintillator, in the few-GeV range relevant to experiments such as DUNE and NOvA. We also present total antineutrino-scintillator quasi-elastic crossmore » sections as a function of energy, which we compare to measurements from previous experiments. As well as being useful to help reduce oscillation experiments' uncertainty, our data can also be used to study the prevalence of various cor relation and final-state interaction effects within the nucleus. We compare to models produced by different model generators, and are able to draw first conclusions about the predictions of these models.« less

Genetic Analysis of Reduced γ-Tocopherol Content in Ethiopian Mustard Seeds.

PubMed

García-Navarro, Elena; Fernández-Martínez, José M; Pérez-Vich, Begoña; Velasco, Leonardo

2016-01-01

Ethiopian mustard (Brassica carinata A. Braun) line BCT-6, with reduced γ-tocopherol content in the seeds, has been previously developed. The objective of this research was to conduct a genetic analysis of seed tocopherols in this line. BCT-6 was crossed with the conventional line C-101 and the F1, F2, and BC plant generations were analyzed. Generation mean analysis using individual scaling tests indicated that reduced γ-tocopherol content fitted an additive-dominant genetic model with predominance of additive effects and absence of epistatic interactions. This was confirmed through a joint scaling test and additional testing of the goodness of fit of the model. Conversely, epistatic interactions were identified for total tocopherol content. Estimation of the minimum number of genes suggested that both γ- and total tocopherol content may be controlled by two genes. A positive correlation between total tocopherol content and the proportion of γ-tocopherol was identified in the F2 generation. Additional research on the feasibility of developing germplasm with high tocopherol content and reduced concentration of γ-tocopherol is required.

Measurement of the antineutrino to neutrino charged-current interaction cross section ratio in MINERvA

NASA Astrophysics Data System (ADS)

Ren, L.; Aliaga, L.; Altinok, O.; Bellantoni, L.; Bercellie, A.; Betancourt, M.; Bodek, A.; Bravar, A.; Budd, H.; Cai, T.; Carneiro, M. F.; da Motta, H.; Devan, J.; Dytman, S. A.; Díaz, G. A.; Eberly, B.; Endress, E.; Felix, J.; Fields, L.; Fine, R.; Gago, A. M.; Galindo, R.; Gallagher, H.; Ghosh, A.; Golan, T.; Gran, R.; Han, J. Y.; Harris, D. A.; Hurtado, K.; Kiveni, M.; Kleykamp, J.; Kordosky, M.; Le, T.; Maher, E.; Manly, S.; Mann, W. A.; Marshall, C. M.; Martinez Caicedo, D. A.; McFarland, K. S.; McGivern, C. L.; McGowan, A. M.; Messerly, B.; Miller, J.; Mislivec, A.; Morfín, J. G.; Mousseau, J.; Naples, D.; Nelson, J. K.; Norrick, A.; Nuruzzaman, Paolone, V.; Park, J.; Patrick, C. E.; Perdue, G. N.; Ramírez, M. A.; Ransome, R. D.; Ray, H.; Rimal, D.; Rodrigues, P. A.; Ruterbories, D.; Schellman, H.; Solano Salinas, C. J.; Sultana, M.; Sánchez Falero, S.; Valencia, E.; Walton, T.; Wolcott, J.; Wospakrik, M.; Yaeggy, B.; MinerνA Collaboration

2017-04-01

We present measurements of the neutrino and antineutrino total charged-current cross sections on carbon and their ratio using the MINERvA scintillator-tracker. The measurements span the energy range 2-22 GeV and were performed using forward and reversed horn focusing modes of the Fermilab low-energy NuMI beam to obtain large neutrino and antineutrino samples. The flux is obtained using a subsample of charged-current events at low hadronic energy transfer along with precise higher energy external neutrino cross section data overlapping with our energy range between 12-22 GeV. We also report on the antineutrino-neutrino cross section ratio, RCC , which does not rely on external normalization information. Our ratio measurement, obtained within the same experiment using the same technique, benefits from the cancellation of common sample systematic uncertainties and reaches a precision of ˜5 % at low energy. Our results for the antineutrino-nucleus scattering cross section and for RCC are the most precise to date in the energy range Eν<6 GeV .

Measurement of the antineutrino to neutrino charged-current interaction cross section ratio in MINERvA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ren, L.; Aliaga, L.; Altinok, O.

Here, we present measurements of the neutrino and antineutrino total charged-current cross sections on carbon and their ratio using the MINERvA scintillator-tracker. The measurements span the energy range 2-22 GeV and were performed using forward and reversed horn focusing modes of the Fermilab low-energy NuMI beam to obtain large neutrino and antineutrino samples. The flux is obtained using a sub-sample of charged-current events at low hadronic energy transfer along with precise higher energy external neutrino cross section data overlapping with our energy range between 12-22 GeV. We also report on the antineutrino-neutrino cross section ratio, Rcc, which does not rely on external normalization information. Our ratio measurement, obtained within the same experiment using the same technique, benefits from the cancellation of common sample systematic uncertainties and reaches a precision of 5% at low energy. Our results for the antineutrino-nucleus scattering cross section and for Rcc are the most precise to date in the energy rangemore » $$E_{\

Interaction between κ- and ι-carrageenan and anthocyanins from Vaccinium myrtillus.

PubMed

Navikaite, Vesta; Simanaviciute, Deimante; Klimaviciute, Rima; Jakstas, Valdas; Ivanauskas, Liudas

2016-09-05

Anthocyanins (ATCs) from the Vaccinium myrtillus water extract have been incorporated into the κ-carrageenan (κ-CARG) or ι-carrageenan (ι-CARG) during complexation in dilute solutions or adsorption onto the microgranules of κ-CARG or ι-CARG cross-linked with epichlorohydrin. At the optimal weight ratio of CARG to ATC at 0.4:1 and the total ATCs and CARG concentration≤0.07g/L, stable dispersions of the κ-CARG/ATCs or ι-CARG/ATCs complex nanosize particles were obtained. The Langmuir, Freundlich and Dubinin-Radushkevich adsorption models have been used to describe the equilibrium adsorption of ATCs on cross-linked CARG. The introduction of ATCs into CARG and cross-linked CARG was confirmed by FT-IR spectroscopy. The data of the HPLC analysis showed that during adsorption on cross-linked ι-CARG microgranules ATCs are isolated from the crude water extract of wild bilberries, whereas other phenolics remain in the adsorption solution. After desorption from cross-linked CARG/ATC into different media the sufficiently pure and stable solutions of ATCs were obtained. Copyright © 2016 Elsevier Ltd. All rights reserved.

Measurement of the antineutrino to neutrino charged-current interaction cross section ratio in MINERvA

DOE PAGES

Ren, L.; Aliaga, L.; Altinok, O.; ...

2017-04-14

Here, we present measurements of the neutrino and antineutrino total charged-current cross sections on carbon and their ratio using the MINERvA scintillator-tracker. The measurements span the energy range 2-22 GeV and were performed using forward and reversed horn focusing modes of the Fermilab low-energy NuMI beam to obtain large neutrino and antineutrino samples. The flux is obtained using a sub-sample of charged-current events at low hadronic energy transfer along with precise higher energy external neutrino cross section data overlapping with our energy range between 12-22 GeV. We also report on the antineutrino-neutrino cross section ratio, Rcc, which does not rely on external normalization information. Our ratio measurement, obtained within the same experiment using the same technique, benefits from the cancellation of common sample systematic uncertainties and reaches a precision of 5% at low energy. Our results for the antineutrino-nucleus scattering cross section and for Rcc are the most precise to date in the energy rangemore » $$E_{\

A comparison of total reaction cross section models used in particle and heavy ion transport codes

NASA Astrophysics Data System (ADS)

Sihver, Lembit; Lantz, M.; Takechi, M.; Kohama, A.; Ferrari, A.; Cerutti, F.; Sato, T.

To be able to calculate the nucleon-nucleus and nucleus-nucleus total reaction cross sections with precision is very important for studies of basic nuclear properties, e.g. nuclear structure. This is also of importance for particle and heavy ion transport calculations because, in all particle and heavy ion transport codes, the probability function that a projectile particle will collide within a certain distance x in the matter depends on the total reaction cross sections. Furthermore, the total reaction cross sections will also scale the calculated partial fragmentation cross sections. It is therefore crucial that accurate total reaction cross section models are used in the transport calculations. In this paper, different models for calculating nucleon-nucleus and nucleus-nucleus total reaction cross sections are compared and discussed.

Production of neutrinos and neutrino-like particles in proton-nucleus interactions. [400 GeV, cross sections

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dishaw, J.P.

1979-03-01

An experimental search was performed to look for the direct production of neutrinos or neutrino-like particles, i.e., neutral particles which interact weakly with hadrons, in proton-nucleus interactions at 400 GeV incident proton energy. Possible sources of such particles include the semi-leptonic decay of new heavy particles such as charm, and the direct production of a light neutral Higgs particle such as the axion. The production of these particles has been inferred in this experiment by energy nonconservation in the collision of a proton with an iron nucleus. The total visible energy of the interaction was measured using a sampling ionizationmore » calorimeter. After correcting for beam intensity effects and cutting the data to eliminate systematic effects in the measurement, the final resolution of the calorimeter was 3.51% and increased with decreasing incident beam energy with a square root dependence on the beam energy. Energy nonconservation in the data is manifest as a non-Gaussian distribution on the low side of the calorimeter measured energy. Model calculations yield the fraction of events expected in this non-Gaussian behavior for the various sources of neutrinos or neutrino-like particles. A maximum likelihood fit to the data with the theoretical fraction of events expected yields the 95% confidence level production cross section upper limit values. The upper limits for general production of neutrino-like particles for various parameterizations of the production cross section are presented. The following specific upper limits have been established: charm particle production < 670 ..mu..barns, supersymmetric particle production carrying an additional quantum number R < 33 ..mu..barns (mass of 1 GeV), 8 ..mu..barns (mass of 3 GeV); axion production < 10/sup -3/ times the ..pi../sup 0/ production cross section. 144 references.« less

Measurement of the absolute v μ-CCQE cross section at the SciBooNE experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aunion, Jose Luis Alcaraz

2010-07-01

This thesis presents the measurement of the charged current quasi-elastic (CCQE) neutrino-nucleon cross section at neutrino energies around 1 GeV. This measurement has two main physical motivations. On one hand, the neutrino-nucleon interactions at few GeV is a region where existing old data are sparse and with low statistics. The current measurement populates low energy regions with higher statistics and precision than previous experiments. On the other hand, the CCQE interaction is the most useful interaction in neutrino oscillation experiments. The CCQE channel is used to measure the initial and final neutrino fluxes in order to determine the neutrino fractionmore » that disappeared. The neutrino oscillation experiments work at low neutrino energies, so precise measurement of CCQE interactions are essential for flux measurements. The main goal of this thesis is to measure the CCQE absolute neutrino cross section from the SciBooNE data. The SciBar Booster Neutrino Experiment (SciBooNE) is a neutrino and anti-neutrino scattering off experiment. The neutrino energy spectrum works at energies around 1 GeV. SciBooNE was running from June 8th 2007 to August 18th 2008. In that period, the experiment collected a total of 2.65 x 10 20 protons on target (POT). This thesis has used full data collection in neutrino mode 0.99 x 10 20 POT. A CCQE selection cut has been performed, achieving around 70% pure CCQE sample. A fit method has been exclusively developed to determine the absolute CCQE cross section, presenting results in a neutrino energy range from 0.2 to 2 GeV. The results are compatible with the NEUT predictions. The SciBooNE measurement has been compared with both Carbon (MiniBoonE) and deuterium (ANL and BNL) target experiments, showing a good agreement in both cases.« less

Synergistic role of ADP and Ca2+ in diastolic myocardial stiffness

PubMed Central

Sequeira, Vasco; Najafi, Aref; McConnell, Mark; Fowler, Ewan D; Bollen, Ilse A E; Wüst, Rob C I; dos Remedios, Cris; Helmes, Michiel; White, Ed; Stienen, Ger J M; Tardiff, Jil; Kuster, Diederik W D; van der Velden, Jolanda

2015-01-01

Abstract Heart failure (HF) with diastolic dysfunction has been attributed to increased myocardial stiffness that limits proper filling of the ventricle. Altered cross-bridge interaction may significantly contribute to high diastolic stiffness, but this has not been shown thus far. Cross-bridge interactions are dependent on cytosolic [Ca2+] and the regeneration of ATP from ADP. Depletion of myocardial energy reserve is a hallmark of HF leading to ADP accumulation and disturbed Ca2+ handling. Here, we investigated if ADP elevation in concert with increased diastolic [Ca2+] promotes diastolic cross-bridge formation and force generation and thereby increases diastolic stiffness. ADP dose-dependently increased force production in the absence of Ca2+ in membrane-permeabilized cardiomyocytes from human hearts. Moreover, physiological levels of ADP increased actomyosin force generation in the presence of Ca2+ both in human and rat membrane-permeabilized cardiomyocytes. Diastolic stress measured at physiological lattice spacing and 37°C in the presence of pathological levels of ADP and diastolic [Ca2+] revealed a 76 ± 1% contribution of cross-bridge interaction to total diastolic stress in rat membrane-permeabilized cardiomyocytes. Inhibition of creatine kinase (CK), which increases cytosolic ADP, in enzyme-isolated intact rat cardiomyocytes impaired diastolic re-lengthening associated with diastolic Ca2+ overload. In isolated Langendorff-perfused rat hearts, CK inhibition increased ventricular stiffness only in the presence of diastolic [Ca2+]. We propose that elevations of intracellular ADP in specific types of cardiac disease, including those where myocardial energy reserve is limited, contribute to diastolic dysfunction by recruiting cross-bridges, even at low Ca2+, and thereby increase myocardial stiffness. Key points Diastolic dysfunction in heart failure patients is evident from stiffening of the passive properties of the ventricular wall. Increased actomyosin interactions may significantly limit diastolic capacity, however, direct evidence is absent. From experiments at the cellular and whole organ level, in humans and rats, we show that actomyosin-related force development contributes significantly to high diastolic stiffness in environments where high ADP and increased diastolic [Ca2+] are present, such as the failing myocardium. Our basal study provides a mechanical mechanism which may partly underlie diastolic dysfunction. PMID:26096258

Cross-sectional and longitudinal associations between different exercise types and food cravings in free-living healthy young adults.

PubMed

Drenowatz, Clemens; Evensen, Line H; Ernstsen, Linda; Blundell, John E; Hand, Gregory A; Shook, Robin P; Hébert, James R; Burgess, Stephanie; Blair, Steven N

2017-11-01

An increase in energy intake due to alterations in hedonic appetite sensations may, at least in part, contribute to lower-than-expected weight loss in exercise interventions. The aim of this study was to examine cross-sectional and longitudinal associations between habitual exercise participation and food cravings in free-living young adults. A total of 417 adults (49% male, 28 ± 4 years) reported frequency and duration of walking, aerobic exercise, resistance exercise and other exercise at baseline and every 3 months over a 12-month period. Food cravings were assessed via the Control of Eating Questionnaire at baseline and 12-month follow-up. Cross-sectional analyses revealed more frequent cravings for chocolate and a greater difficulty to resist food cravings in women compared to men (p < 0.01). Only with resistance exercise significant sex by exercise interaction effects were observed with favorable responses in men but not in women. Significant main effects were shown for walking and aerobic exercise with exercisers reporting more frequent food cravings for chocolate and fruits and greater difficulty to resist eating compared to non-exercisers (p < 0.05). Longitudinal analyses revealed significant interaction effects for other exercise (p < 0.05) with favorable results in men but not women. Furthermore, significant main effects were observed for aerobic exercise, resistance exercise and total exercise with an increase in exercise being associated with a reduced difficulty to resist food cravings (p < 0.05). The association between exercise participation and hedonic appetite sensations varies by exercise type and sex. Even though exercise was associated with more frequent and greater difficulty to food cravings in the cross-sectional analyses, which may be attributed to greater energy demands, longitudinal results indicate beneficial effects of increased exercise on appetite control, particularly in men. Copyright © 2017 Elsevier Ltd. All rights reserved.

Aroma-related cross-modal interactions for sugar reduction in milk desserts: Influence on consumer perception.

PubMed

Alcaire, Florencia; Antúnez, Lucía; Vidal, Leticia; Giménez, Ana; Ares, Gastón

2017-07-01

Reformulation of industrialized products has been regarded as one of the most cost-effective strategies to reduce sugar intake. Although non-nutritive sweeteners have been extensively used to reduce the added sugar content of these products, increasing evidence about the existence of compensatory energy intake mechanisms makes it necessary to develop alternative strategies to achieve rapid sugar reductions. In this context, the aim of the present work was to evaluate aroma-related cross modal interactions for sugar reduction in vanilla milk desserts. In particular, the influence of increasing vanilla concentration and the joint increase of vanilla and starch concentration on consumer sensory and hedonic perception was assessed. Two studies with 100 consumers each were conducted, in which a total of 15 samples were evaluated. For each sample, consumers rated their overall liking and answered a check-all-that-apply (CATA) question comprising 12 flavour and texture terms. Sugar reduction caused significant changes in the flavour and texture characteristics of the desserts. An increase in vanilla concentration had a minor effect on their sensory characteristics. However, increasing both vanilla and starch concentration led to an increase in vanilla flavour and sweetness perception and reduced changes in consumer hedonic perception. These results showed the potential of aroma-related cross modal interactions for minimizing the sensory changes caused by sugar reduction. These strategies could contribute to product reformulation without the need to use non-nutritive sweeteners. Copyright © 2017 Elsevier Ltd. All rights reserved.

Heavy Ion Fragmentation Experiments at the Bevatron

NASA Technical Reports Server (NTRS)

Heckman, H. H.

1975-01-01

Fragmentation processes of heavy nuclei in matter using the heavy-ion capability of the Bevatron were studied. The purpose was to obtain the single particle inclusive spectra of secondary nuclei produced at 0 deg by the fragmentation of heavy ion beam projectiles. The process being examined is B+T yields F + anything, where B is the beam nucleus, T is the target nucleus, and F is the detected fragment. The fragments F are isotopically identified by experimental procedures involving magnetic analysis, energy loss and time-of-flight measurements. Attempts were also made to: (1) measure the total and partial production cross section for all isotopes, (2) test the applicability of high-energy multi-particle interaction theory to nuclear fragmentation, (3) apply the cross-section data and fragmentation probabilities to cosmic ray transport theory, and (4) search for systematic behavior of fragment production as a means to improve existing semi-empirical theories of cross sections.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mislivec, A.; Higuera, A.; Aliaga, L.

Neutrino induced coherent charged pion production on nuclei,more » $$\\overline{v}μA$$→μ ±π ∓A, is a rare inelastic interaction in which the four-momentum squared transferred to the nucleus is nearly zero, leaving it intact. We identify such events in the scintillator of MINERvA by reconstructing |t| from the final state pion and muon momenta and by removing events with evidence of energetic nuclear recoil or production of other final state particles. We measure the total neutrino and antineutrino cross sections as a function of neutrino energy between 2 and 20 GeV and measure flux integrated differential cross sections as a function of Q 2, E π, and θ π. The Q 2 dependence and equality of the neutrino and antineutrino cross sections at finite Q 2 provide a confirmation of Adler’s partial conservation of axial current hypothesis.« less

Laser Assisted Free-Free Transition in Electron - Atom Collision

NASA Technical Reports Server (NTRS)

Sinha, C.; Bhatia, A. K.

2011-01-01

Free-free transition is studied for electron-Hydrogen atom system in ground state at very low incident energies in presence of an external homogeneous, monochromatic and linearly polarized laser field. The incident electron is considered to be dressed by the laser in a non perturbative manner by choosing the Volkov solutions in both the channels. The space part of the scattering wave function for the electron is solved numerically by taking into account the effect of electron exchange, short range as well as of the long range interactions. Laser assisted differential as well as elastic total cross sections are calculated for single photon absorption/emission in the soft photon limit, the laser intensity being much less than the atomic field intensity. A strong suppression is noted in the laser assisted cross sections as compared to the field free situations. Significant difference is noted in the singlet and the triplet cross sections.

Total cross sections for positrons scattered elastically from helium based on new measurements of total ionization cross sections

NASA Technical Reports Server (NTRS)

Diana, L. M.; Chaplin, R. L.; Brooks, D. L.; Adams, J. T.; Reyna, L. K.

1990-01-01

An improved technique is presented for employing the 2.3m spectrometer to measure total ionization cross sections, Q sub ion, for positrons incident on He. The new ionization cross section agree with the values reported earlier. Estimates are also presented of total elastic scattering cross section, Q sub el, obtained by subtracting from total scattering cross sections, Q sub tot, reported in the literature, the Q sub ion and Q sub Ps (total positronium formation cross sections) and total excitation cross sections, Q sub ex, published by another researcher. The Q sub ion and Q sub el measured with the 3m high resolution time-of-flight spectrometer for 54.9eV positrons are in accord with the results from the 2.3m spectrometer. The ionization cross sections are in fair agreement with theory tending for the most part to be higher, especially at 76.3 and 88.5eV. The elastic cross section agree quite well with theory to the vicinity of 50eV, but at 60eV and above the experimental elastic cross sections climb to and remain at about 0.30 pi a sub o sq while the theoretical values steadily decrease.

Axial mass in quasielastic antineutrino-nucleon scattering accompanied by strange-hyperon production

NASA Astrophysics Data System (ADS)

Kuzmin, K. S.; Naumov, V. A.

2009-09-01

Reactions of quasielastic Λ-, Σ--, and Σ0-hyperon production in antineutrino-nucleon interactions are studied. An axial-mass ( M A ) value that agrees with a fit to all accelerator data on exclusive and inclusive νN and νN reactions was extracted from a global statistical analysis of experimental data on differential and total cross sections for Δ Y = 0 and 1 quasielastic reactions of neutrino and antineutrino scattering on various nuclear targets.

The Interaction of Turbulence with Parallel and Perpendicular Shocks: Theory and Observations at 1 au

NASA Astrophysics Data System (ADS)

Adhikari, L.; Zank, G. P.; Hunana, P.; Hu, Q.

2016-12-01

Shocks are thought to be responsible for the amplification of turbulence as well as for generating turbulence throughout the heliosphere. We study the interaction of turbulence with parallel and perpendicular shock waves using the six-coupled-equation turbulence transport model of Zank et al. We model a 1D stationary shock wave using a hyperbolic tangent function and the Rankine-Hugoniot conditions for both a reduced model with four coupled equations and the full model. Eight quasi-parallel and five quasi-perpendicular events in the WIND spacecraft data sets are identified, and we compute the fluctuating magnetic and kinetic energy, the energy in forward and backward propagating modes, the total turbulent energy, the normalized residual energy, and the normalized cross helicity upstream and downstream of the observed shocks. We compare the observed fitted values upstream and downstream of the shock with numerical solutions to our model equations. The comparison shows that our theoretical results are in reasonable agreement with observations for both quasi-parallel and perpendicular shocks. We find that (1) the total turbulent energy, the energy in forward and backward propagating modes, and the normalized residual energy increase across the shock, (2) the normalized cross helicity increases or decreases across the shock, and (3) the correlation length increases upstream and downstream of the shock, and slightly flattens or decreases across the shock.

THE INTERACTION OF TURBULENCE WITH PARALLEL AND PERPENDICULAR SHOCKS: THEORY AND OBSERVATIONS AT 1 au

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adhikari, L.; Zank, G. P.; Hunana, P.

Shocks are thought to be responsible for the amplification of turbulence as well as for generating turbulence throughout the heliosphere. We study the interaction of turbulence with parallel and perpendicular shock waves using the six-coupled-equation turbulence transport model of Zank et al. We model a 1D stationary shock wave using a hyperbolic tangent function and the Rankine–Hugoniot conditions for both a reduced model with four coupled equations and the full model. Eight quasi-parallel and five quasi-perpendicular events in the WIND spacecraft data sets are identified, and we compute the fluctuating magnetic and kinetic energy, the energy in forward and backwardmore » propagating modes, the total turbulent energy, the normalized residual energy, and the normalized cross helicity upstream and downstream of the observed shocks. We compare the observed fitted values upstream and downstream of the shock with numerical solutions to our model equations. The comparison shows that our theoretical results are in reasonable agreement with observations for both quasi-parallel and perpendicular shocks. We find that (1) the total turbulent energy, the energy in forward and backward propagating modes, and the normalized residual energy increase across the shock, (2) the normalized cross helicity increases or decreases across the shock, and (3) the correlation length increases upstream and downstream of the shock, and slightly flattens or decreases across the shock.« less

Bispectral pairwise interacting source analysis for identifying systems of cross-frequency interacting brain sources from electroencephalographic or magnetoencephalographic signals

NASA Astrophysics Data System (ADS)

Chella, Federico; Pizzella, Vittorio; Zappasodi, Filippo; Nolte, Guido; Marzetti, Laura

2016-05-01

Brain cognitive functions arise through the coordinated activity of several brain regions, which actually form complex dynamical systems operating at multiple frequencies. These systems often consist of interacting subsystems, whose characterization is of importance for a complete understanding of the brain interaction processes. To address this issue, we present a technique, namely the bispectral pairwise interacting source analysis (biPISA), for analyzing systems of cross-frequency interacting brain sources when multichannel electroencephalographic (EEG) or magnetoencephalographic (MEG) data are available. Specifically, the biPISA makes it possible to identify one or many subsystems of cross-frequency interacting sources by decomposing the antisymmetric components of the cross-bispectra between EEG or MEG signals, based on the assumption that interactions are pairwise. Thanks to the properties of the antisymmetric components of the cross-bispectra, biPISA is also robust to spurious interactions arising from mixing artifacts, i.e., volume conduction or field spread, which always affect EEG or MEG functional connectivity estimates. This method is an extension of the pairwise interacting source analysis (PISA), which was originally introduced for investigating interactions at the same frequency, to the study of cross-frequency interactions. The effectiveness of this approach is demonstrated in simulations for up to three interacting source pairs and for real MEG recordings of spontaneous brain activity. Simulations show that the performances of biPISA in estimating the phase difference between the interacting sources are affected by the increasing level of noise rather than by the number of the interacting subsystems. The analysis of real MEG data reveals an interaction between two pairs of sources of central mu and beta rhythms, localizing in the proximity of the left and right central sulci.

The size seems to matter or where lies the “asymptopia”?

NASA Astrophysics Data System (ADS)

Petrov, V. A.; Okorokov, V. A.

2018-05-01

We discuss an apparent correlation between the onset of the rising regime for the total cross-sections and the slowdown of the rise of the forward slopes with energy. It is shown that even at highest energies achieved with the large hadron collider (LHC) the proper sizes of the colliding protons comprise the bulk of the interaction region. This seems to witness that the “asymptopia” — a hypothetical “truly asymptotic” regime — lies at energies no less than 𝒪 (100 TeV). In the course of reasoning, we also discuss the question of the dependence of the effective sizes of hadrons in collision on the type of their interaction.

Differential cross sections for ionizations of H and H2 by 75 keV proton impact

NASA Astrophysics Data System (ADS)

Igarashi, A.; Gulyás, L.

2018-02-01

We have calculated total, partial and fully differential cross sections (FDCSs) for ionizations of H and H2 by 75 keV proton impact within the framework of the continuum-distorted-wave-eikonal-initial-state (CDW-EIS) approximation. Applying the single active electron model, the interaction between the projectile and the target ion is taken into account in the impact parameter picture. Extension of the CDW-EIS model to the molecular target is performed using the two-effective center approximation. The obtained results are compared with those of experimental and other theoretical data when available. The agreements between the theories and the experimental data are generally reasonable except for some cases of the FDCSs.

Low social interactions in eating disorder patients in childhood and adulthood: a multi-centre European case control study.

PubMed

Krug, Isabel; Penelo, Eva; Fernandez-Aranda, Fernando; Anderluh, Marija; Bellodi, Laura; Cellini, Elena; di Bernardo, Milena; Granero, Roser; Karwautz, Andreas; Nacmias, Benedetta; Ricca, Valdo; Sorbi, Sandro; Tchanturia, Kate; Wagner, Gudrun; Collier, David; Treasure, Janet

2013-01-01

The objective of this article was to examine lifestyle behaviours in eating disorder (ED) patients and healthy controls. A total of 801 ED patients and 727 healthy controls from five European countries completed the questions related to lifestyle behaviours of the Cross-Cultural Questionnaire (CCQ). For children, the ED sample exhibited more solitary activities (rigorously doing homework [p<0.001] and watching TV [p<0.05] and less socializing with friends [p<0.05]) than the healthy control group and this continued in adulthood. There were minimal differences across ED sub-diagnoses and various cross-cultural differences emerged. Reduced social activities may be an important risk and maintaining factor for ED symptomatology.

Simultaneous production of lepton pairs in ultraperipheral relativistic heavy ion collisions

NASA Astrophysics Data System (ADS)

Kurban, E.; Güçlü, M. C.

2017-10-01

We calculate the total cross sections and probabilities of electromagnetic productions of electron, muon, and tauon pairs simultaneously. At the CERN Large Hadron Collider (LHC), the available electromagnetic energy is sufficient to produce all kinds of leptons coherently. The masses of muons and tauons are large, so their Compton wavelengths are small enough to interact with the colliding nuclei. Therefore, the realistic nuclear form factors are included in the calculations of electromagnetic pair productions. The cross section calculations show that, at LHC energies, the probabilities of simultaneous productions of all kinds of leptons are increased significantly compared to energies available at the BNL Relativistic Heavy Ion Collider (RHIC) . Experimentally, observing this simultaneous production can give us important information about strong QED.

Potential Energy Curves and Transport Properties for the Interaction of He with Other Ground-state Atoms

NASA Technical Reports Server (NTRS)

Partridge, Harry; Stallcop, James R.; Levin, Eugene; Arnold, Jim (Technical Monitor)

2001-01-01

The interactions of a He atom with a heavier atom are examined for 26 different elements, which are consecutive members selected from three rows (Li - Ne, Na - Ar, and K,Ca, Ga - Kr) and column 12 (Zn,Cd) of the periodic table. Interaction energies are determined wing high-quality ab initio calculations for the states of the molecule that would be formed from each pair of atoms in their ground states. Potential energies are tabulated for a broad range of Interatomic separation distances. The results show, for example, that the energy of an alkali interaction at small separations is nearly the same as that of a rare-gas interaction with the same electron configuration for the dosed shells. Furthermore, the repulsive-range parameter for this region is very short compared to its length for the repulsion dominated by the alkali-valence electron at large separations (beyond about 3-4 a(sub 0)). The potential energies in the region of the van der Waals minimum agree well with the most accurate results available. The ab initio energies are applied to calculate scattering cross sections and obtain the collision integrals that are needed to determine transport properties to second order. The theoretical values of Li-He total scattering cross sections and the rare-gas atom-He transport properties agree well (to within about 1%) with the corresponding measured data. Effective potential energies are constructed from the ab initio energies; the results have been shown to reproduce known transport data and can be readily applied to predict unknown transport properties for like-atom interactions.

Electron impact scattering study of hypohalous acids HOX (X = F, Cl, Br, I)

NASA Astrophysics Data System (ADS)

Yadav, Hitesh; Bhutadia, Harshad; Prajapati, Dinesh; Desai, Hardik; Vinodkumar, Minaxi; Vinodkumar, P. C.

2018-05-01

In this article we aim to report total cross sections (TCS) QT, total elastic cross sections (Qel), total inelastic cross sections (Qinel) i.e. (total ionizations cross sections (Qion)+total electronic excitation cross sections (Qexc)) from threshold of the target to 5000 eV energy range. We have used a well-defined theoretical methodology Spherical Complex Optical Potential (SCOP) to compute QT, Qel and Qinel and Complex Scattering Potential - ionization contribution (CSP - ic) method to report the (Qion). The cross-sectional data reported here for the Hypohalous Acids is for the first time and the present data can become a guideline for the experimentalist to study these targets.

Comparison of photon attenuation coefficients (2-150 KeV) for diagnostic imaging simulations

NASA Astrophysics Data System (ADS)

Dodge, Charles W., III; Flynn, Michael J.

2004-05-01

The Radiology Research Laboratory at the Henry Ford Hospital has been involved in modeling x-ray units in order to predict image quality. A critical part of that modeling process is the accurate choice of interaction coefficients. This paper serves as a review and comparison of existing interaction models. Our objective was to obtain accurate and easily calculated interaction coefficients, at diagnostically relevant energies. We obtained data from: McMaster, Lawrence Berkeley Lab data (LBL), XCOM and FFAST Data from NIST, and the EPDL-97 database via LLNL. Our studies involve low energy photons; therefore, comparisons were limited to Coherent (Rayleigh), Incoherent (Compton) and Photoelectric effects, which were summed to determine a total interaction cross section. Without measured data, it becomes difficult to definitively choose the most accurate method. However, known limitations in the McMaster data and smoothing of photo-edge transitions can be used as a guide to establish more valid approaches. Each method was compared to one another graphically and at individual points. We found that agreement between all methods was excellent when away from photo-edges. Near photo-edges and at low energies, most methods were less accurate. Only the Chanter (FFAST) data seems to have consistently and accurately predicted the placement of edges (through M-shell), while minimizing smoothing errors. The EPDL-97 data by LLNL was the best over method in predicting coherent and incoherent cross sections.

Triple-parton scatterings in proton-nucleus collisions at high energies

NASA Astrophysics Data System (ADS)

d'Enterria, David; Snigirev, Alexander M.

2018-05-01

A generic expression to compute triple-parton scattering (TPS) cross sections in high-energy proton-nucleus (pA) collisions is derived as a function of the corresponding single-parton cross sections and an effective parameter encoding the transverse parton profile of the proton. The TPS cross sections are enhanced by a factor of about 9 A˜eq 2000 in pPb as compared to those in proton-nucleon collisions at the same center-of-mass energy. Estimates for triple charm (c\\overline{c}) and bottom (b\\overline{b}) production in pPb collisions at LHC and FCC energies are presented based on next-to-next-to-leading-order calculations for c\\overline{c} and b\\overline{b} single-parton cross sections. At √{s_{_{sc {nn}}}}= 8.8 TeV, about 10% of the pPb events have three c\\overline{c} pairs produced in separate partonic interactions. At √{s_{_{sc {nn}}}}= 63 TeV, the pPb cross sections for triple-J/ψ and triple-b\\overline{b} are O(1-10 mb). In the most energetic collisions of cosmic rays in the upper atmosphere, equivalent to √{s_{_{sc {nn}}}}≈ 400 TeV, the TPS c\\overline{c} cross section equals the total p-Air inelastic cross section.

Considerations about projectile and target X-rays induced during heavy ion bombardment

NASA Astrophysics Data System (ADS)

Fernandes, F.; Bauer, D. V.; Duarte, A.; Ferrari, T. M.; Niekraszewicz, L. A. B.; Amaral, L.; Dias, J. F.

2018-02-01

In this work we present some results concerning the X-rays emitted by heavy ions during target bombardment. In this case, Cl4+ and Cl5+ ions with energies from 4 MeV to 10 MeV were employed to irradiate vitreous carbon planchets. Moreover, total X-ray production cross sections of titanium X-rays induced by chlorine ions were obtained as well for the same energy range. Only inner shell transitions were considered in the present work. The titanium target consisted of a thin film deposited over vitreous carbon planchets. The results indicate that the projectile X-ray yields increase as a function of the bombarding energy for the present energy range. Effects due to projectile charge state appears to be of minor importance at these low ion velocities. It is shown that a simple exponential function can represent the continuum background of such complex spectra. The chlorine transition rates Kβ/Kα obtained from chlorine acting as a projectile interacting with a carbon target are about half the value when compared to the chlorine Kβ/Kα ratios obtained when a LiCl target is bombarded with C+ and C3+ ions with energies from 2 MeV to 6 MeV. As far as the total X-ray production cross sections of Ti induced by chlorine ions are concerned, the ECPSSR theory underestimates the Ti total X-rays production cross sections by several orders of magnitude. The role of electron capture and possible mechanisms responsible for these effects are discussed.

Study of intermolecular contacts in proteins and oligomer interfaces and preliminary investigations into the design and production of nanomaterials from proteins

NASA Astrophysics Data System (ADS)

Iyer, Ganesh Hariharan

The first part of this research involved a study of the nature and extent of nonbonded interactions at crystal and oligomer interfaces. A survey was compiled of several characteristics of intersubunit contacts in 58 different oligomeric proteins, and of the intermolecular contacts in 223 protein crystal structures. Routines written in "S" language were utilized for the generation of the observed and expected contacts. The information in the Protein Data Bank (PDB) was extracted using the database management system, Protein Knowledge Base (PKB). Potentials of mean force for atom-atom contacts and residue-residue contacts were derived by comparison of the number of observed interactions with the number expected by mass action. Preference association matrices and log-linear analyses were applied to determine the different factors that could contribute to the overall interactions at the interfaces of oligomers and crystals. Surface patches at oligomer and crystal interfaces were also studied to further investigate the origin of the differences in their stabilities. Total number of atoms in contact and the secondary structure elements involved are similar in the two types of interfaces. Crystal contacts result from more numerous interactions by polar residues, compared with a tendency toward nonpolar amino acid prominent in oligomer interfaces. Contact potentials indicate that hydrophobic interactions at oligomer interfaces favor aromatic amino acids and methionine over aliphatic amino acids; and that crystal contacts form in such a way as to avoid inclusion of hydrophobic interactions. The second part involved the development of a new class of biomaterials from two-dimensional arrays of ordered proteins. Point mutations were planned to introduce cysteine residues at appropriate locations to enable cross-linking at the molecular interface within given crystallographic planes. Crystallization and subsequent cross-linking of the modified protein would lead to the formation of arrays on subsequent dissociation of the crystal. Novel protein architectures can be generated from these cross-linked nanostructures. Experiments with model protein, maltose-binding protein (MBP) were performed to develop purification, cross-linking and crystallization techniques. The long-term goal of this project is to apply the experience gained with MBP to the fabrication of nanomaterials from other, application-specific proteins for ultrafiltration and microelectronic devices.

First Measurement of Monoenergetic Muon Neutrino Charged Current Interactions

NASA Astrophysics Data System (ADS)

Aguilar-Arevalo, A. A.; Brown, B. C.; Bugel, L.; Cheng, G.; Church, E. D.; Conrad, J. M.; Cooper, R. L.; Dharmapalan, R.; Djurcic, Z.; Finley, D. A.; Fitzpatrick, R. S.; Ford, R.; Garcia, F. G.; Garvey, G. T.; Grange, J.; Huelsnitz, W.; Ignarra, C.; Imlay, R.; Johnson, R. A.; Jordan, J. R.; Karagiorgi, G.; Katori, T.; Kobilarcik, T.; Louis, W. C.; Mahn, K.; Mariani, C.; Marsh, W.; Mills, G. B.; Mirabal, J.; Moore, C. D.; Mousseau, J.; Nienaber, P.; Osmanov, B.; Pavlovic, Z.; Perevalov, D.; Ray, H.; Roe, B. P.; Russell, A. D.; Shaevitz, M. H.; Spitz, J.; Stancu, I.; Tayloe, R.; Thornton, R. T.; Van de Water, R. G.; Wascko, M. O.; White, D. H.; Wickremasinghe, D. A.; Zeller, G. P.; Zimmerman, E. D.; MiniBooNE Collaboration

2018-04-01

We report the first measurement of monoenergetic muon neutrino charged current interactions. MiniBooNE has isolated 236 MeV muon neutrino events originating from charged kaon decay at rest (K+→μ+νμ) at the NuMI beamline absorber. These signal νμ -carbon events are distinguished from primarily pion decay in flight νμ and ν¯μ backgrounds produced at the target station and decay pipe using their arrival time and reconstructed muon energy. The significance of the signal observation is at the 3.9 σ level. The muon kinetic energy, neutrino-nucleus energy transfer (ω =Eν-Eμ), and total cross section for these events are extracted. This result is the first known-energy, weak-interaction-only probe of the nucleus to yield a measurement of ω using neutrinos, a quantity thus far only accessible through electron scattering.

Extracting nuclear sizes of medium to heavy nuclei from total reaction cross sections

NASA Astrophysics Data System (ADS)

Horiuchi, W.; Hatakeyama, S.; Ebata, S.; Suzuki, Y.

2016-04-01

Background: Proton and neutron radii are fundamental quantities of atomic nuclei. To study the sizes of short-lived unstable nuclei, there is a need for an alternative to electron scattering. Purpose: The recent paper by Horiuchi et al. [Phys. Rev. C 89, 011601(R) (2014)], 10.1103/PhysRevC.89.011601 proposed a possible way of extracting the matter and neutron-skin thickness of light- to medium-mass nuclei using total reaction cross section, σR. The analysis is extended to medium to heavy nuclei up to lead isotopes with due attention to Coulomb breakup contributions as well as density distributions improved by paring correlation. Methods: We formulate a quantitative calculation of σR based on the Glauber model including the Coulomb breakup. To substantiate the treatment of the Coulomb breakup, we also evaluate the Coulomb breakup cross section due to the electric dipole field in a canonical-basis-time-dependent-Hartree-Fock-Bogoliubov theory in the three-dimensional coordinate space. Results: We analyze σR's of 103 nuclei with Z =20 , 28, 40, 50, 70, and 82 incident on light targets, H,21, 4He, and 12C. Three kinds of Skyrme interactions are tested to generate those wave functions. To discuss possible uncertainty due to the Coulomb breakup, we examine its dependence on the target, the incident energy, and the Skyrme interaction. The proton is a most promising target for extracting the nuclear sizes as the Coulomb excitation can safely be neglected. We find that the so-called reaction radius, aR=√{σR/π } , for the proton target is very well approximated by a linear function of two variables, the matter radius and the skin thickness, in which three constants depend only on the incident energy. We quantify the accuracy of σR measurements needed to extract the nuclear sizes. Conclusions: The proton is the best target because, once the incident energy is set, its aR is very accurately determined by only the matter radius and neutron-skin thickness. If σR's at different incident energies are measured, one can determine both the proton and neutron radii for unstable nuclei as well. The total reaction cross sections calculated in this paper are given as Supplemental Material for the sake of future measurements.

Potential interaction between transport and stream networks over the lowland rivers in Eastern India.

PubMed

Roy, Suvendu; Sahu, Abhay Sankar

2017-07-15

Extension of transport networks supports good accessibility and associated with the development of a region. However, transport lines have fragmented the regional landscape and disturbed the natural interplay between rivers and their floodplains. Spatial analysis using multiple buffers provides information about the potential interaction between road and stream networks and their impact on channel morphology of a small watershed in the Lower Gangetic Plain. Present study is tried to understand the lateral and longitudinal disconnection in headwater stream by rural roads with the integration of geoinformatics and field survey. Significant (p < 0.001) growth of total road length and number of road-stream crossing in the last five decades (1970s-2010s) contribute to making longitudinal and lateral disconnection in the fluvial system of Kunur River Basin. Channel geometry from ten road-stream crossings shows significant (p = 0.01) differences between upstream and downstream of crossing structure and created problems like downstream scouring, increased drop height at outlet, formation of stable bars, severe bank erosion, and make barriers for river biota. The hydro-geomorphic processes are also adversely affected due to lateral disconnection and input of fine to coarse sediments from the river side growth of unpaved road (1922%). Limited streamside development, delineation of stream corridor, regular monitoring and engineering efficiency for the construction of road and road-stream crossing might be effective in managing river geomorphology and riverine landscape. Copyright © 2017 Elsevier Ltd. All rights reserved.

Electron capture in collisions of N^+ with H and H^+ with N

NASA Astrophysics Data System (ADS)

Lin, C. Y.; Stancil, P. C.; Gu, J. P.; Buenker, R. J.; Kimura, M.

2004-05-01

Charge transfer processes due to collisions of N^+ with atomic hydrogen and H^+ with atomic nitrogen are investigated using the quantum-mechanical molecular-orbital close-coupling (MOCC) method. The MOCC calculations utilize ab initio adiabatic potential curves and nonadiabatic radial and rotational coupling matrix elements obtained with the multireference single- and double-excitation configuration interaction approach. Total and state-selective cross sections for the energy range 0.1-500 eV/u will be presented and compared with existing experimental and theoretical data.

Superscaling in electron-nucleus scattering and its link to CC and NC QE neutrino-nucleus scattering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barbaro, M. B.; Amaro, J. E.; Caballero, J. A.

2015-05-15

The superscaling approach (SuSA) to neutrino-nucleus scattering, based on the assumed universality of the scaling function for electromagnetic and weak interactions, is reviewed. The predictions of the SuSA model for bot CC and NC differential and total cross sections are presented and compared with the MiniBooNE data. The role of scaling violations, in particular the contribution of meson exchange currents in the two-particle two-hole sector, is explored.

Modifying Influence of Dietary Sugar in the Relationship Between Cortisol and Visceral Adipose Tissue in Minority Youth

PubMed Central

Gyllenhammer, Lauren E.; Weigensberg, Marc J.; Spruijt-Metz, Donna; Allayee, Hooman; Goran, Michael I.; Davis, Jaimie N.

2013-01-01

Objective Cortisol has been associated with preferential visceral adipose tissue (VAT) deposition; however findings in humans are mixed, which may be clarified when diet is considered. Design and Methods Participants included 165 African American and Latino, overweight adolescents (BMI% 97.2±3.2%, ages 13-18, 67% Latino, 66% female). Body composition was determined by DEXA, abdominal fat depots (VAT, subcutaneous (SAT)) by multiple-slice MRI, time-controlled serum sample to measure cortisol, and 2-day multi-pass 24-hour dietary recall. Linear regression analysis examined the cross-sectional relationship between cortisol, and the interaction of diet and cortisol on adiposity measures. Sex, race, age and total body fat were a priori covariates. Results There was a significant interaction between cortisol and sugar (total and added) in the prediction of VAT (pinteraction<=0.05). Amongst participants with high total or added-sugar intake, cortisol was significantly associated with VAT (β=0.031 p<0.001; β=0.026 p<0.001), with no relationship in low consumers of total or added-sugar. Conclusion Dietary sugar may play an important role in modifying the relationship between cortisol and VAT, such that cortisol is significantly associated with elevated VAT under conditions of high sugar intake. PMID:23929660

Circular polarization of X-ray radiation emitted by longitudinally polarized electron impact excitation: Under a screened Coulomb interaction

NASA Astrophysics Data System (ADS)

Chen, Zhan-Bin

2017-12-01

Longitudinally polarized electron impact excitation from the ground state 1s2 to the excited state 1s2l (l =s,p) levels of highly charged He-like Fe24+ ions in weakly coupled hot-dense plasmas is investigated using a fully relativistic distorted-wave method. The Debye-Hückel potential is used to describe the plasma screening. Benchmark results such as the total cross sections, the magnetic sublevels cross sections, and the circular polarizations of corresponding X-ray radiations are presented. For the excitation process, results show that the plasma screening has an effect in reducing both the total and magnetic sublevels cross sections. For the de-excitation process, it is found that while the plasma screening as a slightly effect on the circular polarizations of radiations for the 1 s 2 s 3S1 → 1 s21S0,1 s 2 p 3P2 → 1 s21S0 , and 1 s 2 p 1P1 → 1 s21S0 transition lines, it gives a substantial contribution for the same properties of the 1 s 2 p 3P1 → 1 s21S0 line.

Earth Versus Neutrinos: Measuring the Total Muon-Neutrino-to-Nucleon Cross Section at Ultra-High Energies through Differential Earth Absorption of Muon Neutrinos from Cosmic Rays Using the IceCube Detector

NASA Astrophysics Data System (ADS)

Miarecki, Sandra Christine

The IceCube Neutrino Detector at the South Pole was constructed to measure the flux of high-energy neutrinos and to try to identify their cosmic sources. In addition to these astrophysical neutrinos, IceCube also detects the neutrinos that result from cosmic ray interactions with the atmosphere. These atmospheric neutrinos can be used to measure the total muon neutrino-to-nucleon cross section by measuring neutrino absorption in the Earth. The measurement involves isolating a sample of 10,784 Earth-transiting muons detected by IceCube in its 79-string configuration. The cross-section is determined using a two-dimensional fit in measured muon energy and zenith angle and is presented as a multiple of the Standard Model expectation as calculated by Cooper-Sarkar, Mertsch, and Sarkar in 2011. A multiple of 1.0 would indicate agreement with the Standard Model. The results of this analysis find the multiple to be 1.30 (+0.21 -0.19 statistical) (+0.40 -0.44 systematic) for the neutrino energy range of 6.3 to 980 TeV, which is in agreement with the Standard Model expectation.

Ab initio calculation of atomic interactions on Al(110): implications for epitaxial growth

NASA Astrophysics Data System (ADS)

Fichthorn, Kristen; Tiwary, Yogesh

2007-03-01

Using first-principles calculations based on density-functional theory, we resolved atomic interactions between adsorbed Al atoms on Al(110). Relevant pair and trio interactions were quantified. We find that pair interactions extend to the third in-channel and second cross-channel neighbor on the anisotropic (110) surface. Beyond these distances, pair interactions are negligible. The nearest-neighbor interaction in the in-channel direction is attractive, but nearest-neighbor cross-channel interaction is repulsive. While nearest-neighbor, cross-channel repulsion does not support the experimental observation of 3D hut formation in Al/Al(110) homoepitaxial growth [1], we find that trio interactions can be significant and attractive and they support cross-channel bonding. The pair and trio interactions have direct and indirect components. We have quantified the electronic and elastic components of the indirect, substrate-mediated interactions. We also probe the influence of these interactions on the energy barriers for adatom hopping. [1] F. Buatier de Mongeot, W. Zhu, A. Molle, R. Buzio, C. Boragno, U. Valbusa, E. Wang, and Z. Zhang, Phys. Rev. Lett. 91, 016102 (2003).

Photoeffect cross sections of some rare-earth elements at 145.4 keV

NASA Astrophysics Data System (ADS)

Umesh, T. K.; Ranganathaiah, C.; Sanjeevaiah, B.

1985-08-01

Total attenuation cross sections in the elements La, Ce, Pr, Nd, Sm, Gd, Dy, Ho, and Er were derived from the measured total cross sections of their simple oxide compounds, by employing the mixture rule at 145.4-keV photon energy. The compound cross sections have been measured by performing transmission experiments in a good geometry setup. From the derived total cross sections of elements, photoeffect cross sections have been obtained by subtracting the theoretical scattering cross sections. A good agreement is observed between the present data of photoeffect cross sections and Scofield's theoretical data.

"Man, This Is Hard": A Case Study of How Race and Religion Affect Cross-Racial Interaction for Black Students

ERIC Educational Resources Information Center

Park, Julie J.

2012-01-01

This study examines how multiple facets of students' identities affect their experiences with cross-racial interaction. I consider how the intersection between two identity categories--race and religion--affected six Black students' experiences with cross-racial interaction in a multiracial religious student organization. While the pursuit of…

Osmotic second virial cross-coefficient measurements for binary combination of lysozyme, ovalbumin, and α-amylase in salt solutions.

PubMed

Mehta, Chirag M; White, Edward T; Litster, James D

2013-01-01

Interactions measurement is a valuable tool to predict equilibrium phase separation of a desired protein in the presence of unwanted macromolecules. In this study, cross-interactions were measured as the osmotic second virial cross-coefficients (B23 ) for the three binary protein systems involving lysozyme, ovalbumin, and α-amylase in salt solutions (sodium chloride and ammonium sulfate). They were correlated with solubility for the binary protein mixtures. The cross-interaction behavior at different salt concentrations was interpreted by either electrostatic or hydrophobic interaction forces. At low salt concentrations, the protein surface charge dominates cross-interaction behavior as a function of pH. With added ovalbumin, the lysozyme solubility decreased linearly at low salt concentration in sodium chloride and increased at high salt concentration in ammonium sulfate. The B23 value was found to be proportional to the slope of the lysozyme solubility against ovalbumin concentration and the correlation was explained by preferential interaction theory. © 2013 American Institute of Chemical Engineers.

Genetically encoded releasable photo-cross-linking strategies for studying protein-protein interactions in living cells.

PubMed

Yang, Yi; Song, Haiping; He, Dan; Zhang, Shuai; Dai, Shizhong; Xie, Xiao; Lin, Shixian; Hao, Ziyang; Zheng, Huangtao; Chen, Peng R

2017-10-01

Although protein-protein interactions (PPIs) have crucial roles in virtually all cellular processes, the identification of more transient interactions in their biological context remains challenging. Conventional photo-cross-linking strategies can be used to identify transient interactions, but these approaches often suffer from high background due to the cross-linked bait proteins. To solve the problem, we have developed membrane-permeable releasable photo-cross-linkers that allow for prey-bait separation after protein complex isolation and can be installed in proteins of interest (POIs) as unnatural amino acids. Here we describe the procedures for using two releasable photo-cross-linkers, DiZSeK and DiZHSeC, in both living Escherichia coli and mammalian cells. A cleavage after protein photo-cross-linking (CAPP ) strategy based on the photo-cross-linker DiZSeK is described, in which the prey protein pool is released from a POI after affinity purification. Prey proteins are analyzed using mass spectrometry or 2D gel electrophoresis for global comparison of interactomes from different experimental conditions. An in situ cleavage and mass spectrometry (MS)-label transfer after protein photo-cross-linking (IMAPP) strategy based on the photo-cross-linker DiZHSeC is also described. This strategy can be used for the identification of cross-linking sites to allow detailed characterization of PPI interfaces. The procedures for photo-cross-linker incorporation, photo-cross-linking of interaction partners and affinity purification of cross-linked complexes are similar for the two photo-cross-linkers. The final section of the protocol describes prey-bait separation (for CAPP) and MS-label transfer and identification (for IMAPP). After plasmid construction, the CAPP and IMAPP strategies can be completed within 6 and 7 d, respectively.

Total Ambient Dose Equivalent Buildup Factor Determination for Nbs04 Concrete.

PubMed

Duckic, Paulina; Hayes, Robert B

2018-06-01

Buildup factors are dimensionless multiplicative factors required by the point kernel method to account for scattered radiation through a shielding material. The accuracy of the point kernel method is strongly affected by the correspondence of analyzed parameters to experimental configurations, which is attempted to be simplified here. The point kernel method has not been found to have widespread practical use for neutron shielding calculations due to the complex neutron transport behavior through shielding materials (i.e. the variety of interaction mechanisms that neutrons may undergo while traversing the shield) as well as non-linear neutron total cross section energy dependence. In this work, total ambient dose buildup factors for NBS04 concrete are calculated in terms of neutron and secondary gamma ray transmission factors. The neutron and secondary gamma ray transmission factors are calculated using MCNP6™ code with updated cross sections. Both transmission factors and buildup factors are given in a tabulated form. Practical use of neutron transmission and buildup factors warrants rigorously calculated results with all associated uncertainties. In this work, sensitivity analysis of neutron transmission factors and total buildup factors with varying water content has been conducted. The analysis showed significant impact of varying water content in concrete on both neutron transmission factors and total buildup factors. Finally, support vector regression, a machine learning technique, has been engaged to make a model based on the calculated data for calculation of the buildup factors. The developed model can predict most of the data with 20% relative error.

The interaction between erectile dysfunction complaints and depression in men: a cross-sectional study about sleep, hormones and quality of life.

PubMed

Soterio-Pires, J H; Hirotsu, C; Kim, L J; Bittencourt, L; Tufik, S; Andersen, M L

2017-03-01

Depression (DEP) is one of the main disabling diseases and is considered a contributor factor for erectile dysfunction (ED). Both of these conditions may be associated with hormonal changes and sleep disturbances. We aimed to evaluate the interaction between ED complaints and depression symptoms on sleep parameters, hormone levels and quality of life in men. This was a cross-sectional study of 468 men aged 20-80 years. The participants were classified according to the presence of ED and/or DEP in groups of healthy individuals, ED, DEP and DEP with ED (DEP-ED). All participants completed questionnaires about sleep, clinical history and quality of life, and underwent polysomnography with blood collection the following morning. ED participants showed higher frequency of insomnia symptoms (65.5%), whereas DEP group had more complaints of difficulty in falling asleep and early morning awakening. In the polysomnography, all groups showed similar parameters. No differences were found in cortisol and total testosterone levels; however, free testosterone levels and the physiological domain of quality of life were lower in DEP-ED group. ED and DEP, as independent factors, negatively affected subjective sleep parameters. The interaction between these factors led to a low quality of life and was related to a decrease in free testosterone levels.

The role of self-interacting right-handed neutrinos in galactic structure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Argüelles, C.R.; Rueda, J.A.; Ruffini, R.

2016-04-01

It has been shown previously that the DM in galactic halos can be explained by a self-gravitating system of massive keV fermions ('inos') in thermodynamic equilibrium, and predicted the existence of a denser quantum core of inos towards the center of galaxies. In this article we show that the inclusion of self-interactions among the inos, modeled within a relativistic mean-field-theory approach, allows the quantum core to become massive and compact enough to explain the dynamics of the S-cluster stars closest to the Milky Way's galactic center. The application of this model to other galaxies such as large elliptical harboring massivemore » central dark objects of ∼ 10{sup 9} M {sub ⊙} is also investigated. We identify these interacting inos with sterile right-handed neutrinos pertaining to minimal extensions of the Standard Model, and calculate the corresponding total cross-section σ within an electroweak-like formalism to be compared with other observationally inferred cross-section estimates. The coincidence of an ino mass range of few tens of keV derived here only from the galactic structure, with the range obtained independently from other astrophysical and cosmological constraints, points towards an important role of the right-handed neutrinos in the cosmic structure.« less

Measurement of the neutral to charged current cross section ratios for neutrino and and antineutrino interactions on protons

NASA Astrophysics Data System (ADS)

Jones, G. T.; Jones, R. W. L.; Kennedy, B. W.; O'Neale, S. W.; Hoffmann, E.; Haidt, D.; Klein, H.; Mittendorfer, J.; Morrison, D. R. O.; Schmid, P.; Wachsmuth, H.; Hamisi, F.; Miller, D. B.; Mobayyen, M. M.; Aderholz, M.; Deck, L.; Schmitz, N.; Wittek, W.; Corrigan, G.; Myatt, G.; Radojicic, D.; Retter, M. L.; Saitta, B.; Shotton, P. N.; Towers, S. J.; Bullock, F. W.; Burke, S.; Fitch, P. J.; Birmingham-Bonn-CERN-Imperial College-München(MPI)-Oxford-University College Collaboration

1986-10-01

The ratios Rvp and Rvp of the neutral current to charged current cross sections for neutrino and antineutrino interactions on protons have been measured in BEBC. The beam was the CERN SPS 400 GeV wideband beam. The bubble chamber, equipped with the standard External Muon Identifier, was surrounded with an additional plane of wire chambers (Internal Picket Fence), which was added to improve neutral current event identification. For a total transverse momentum of the charged hadrons above 0.45 GeV/ c and a charged multiplicity of at least 3, it was found that R vp = 0.384 ± 0.015 and R vp = 0.338 ± 0.014 ± 0.016, corresponding to a value of sin 2θ w(M woverlineMSof 0.225 ± 0.030 . Combining the results from hydrogen and an isoscalar target, the differences of the neutral current chiral coupling constants were found to be u2l- d2L = -0.080 ± 0.043 ± 0.012 and u2R- d2R = 0.021±0.055±0.028.

Quasi-four-body treatment of charge transfer in the collision of protons with atomic helium: II. Second-order non-Thomas mechanisms and the cross sections

NASA Astrophysics Data System (ADS)

Safarzade, Zohre; Akbarabadi, Farideh Shojaei; Fathi, Reza; Brunger, Michael J.; Bolorizadeh, Mohammad A.

2018-05-01

A fully quantum mechanical four-body treatment of charge transfer collisions between energetic protons and atomic helium is developed here. The Pauli exclusion principle is applied to both the wave function of the initial and final states as well as the operators involved in the interaction. Prior to the collision, the helium atom is assumed as a two-body system composed of the nucleus, He2+, and an electron cloud composed of two electrons. Nonetheless, four particles are assumed in the final state. As the double interactions contribute extensively in single charge transfer collisions, the Faddeev-Lovelace-Watson scattering formalism describes it best physically. The treatment of the charge transfer cross section, under this quasi-four-body treatment within the FWL formalism, showed that other mechanisms leading to an effect similar to the Thomas one occur at the same scattering angle. Here, we study the two-body interactions which are not classically described but which lead to an effect similar to the Thomas mechanism and finally we calculate the total singlet and triplet amplitudes as well as the angular distributions of the charge transfer cross sections. As the incoming projectiles are assumed to be plane waves, the present results are calculated for high energies; specifically a projectile energy of 7.42 MeV was assumed as this is where experimental results are available in the literature for comparison. Finally, when possible we compare the present results with the other available theoretical data.

Elastic and inelastic photoproduction of J/ ψ mesons at HERA

NASA Astrophysics Data System (ADS)

Aid, S.; Andreev, V.; Andrieu, B.; Appuhn, R.-D.; Arpagaus, M.; Babaev, A.; Bähr, J.; Bán, J.; Ban, Y.; Baranov, P.; Barrelet, E.; Barschke, R.; Bartel, W.; Barth, M.; Bassler, U.; Beck, H. P.; Behrend, H.-J.; Belousov, A.; Berger, Ch.; Bernardi, G.; Bernet, R.; Bertrand-Coremans, G.; Besançon, M.; Beyer, R.; Biddulph, P.; Bispham, P.; Bizot, J. C.; Blobel, V.; Borras, K.; Botterweck, F.; Boudry, V.; Braemer, A.; Braunschweig, W.; Brisson, V.; Bruncko, D.; Brune, C.; Buchholz, R.; Büngener, L.; Bürger, J.; Büsser, F. W.; Buniatian, A.; Burke, S.; Burton, M. J.; Buschhorn, G.; Campbell, A. J.; Carli, T.; Charles, F.; Charlet, M.; Clarke, D.; Clegg, A. B.; Clerbaux, B.; Cocks, S.; Contreras, J. G.; Cormack, C.; Coughlan, J. A.; Courau, A.; Cousinou, M.-C.; Cozzika, G.; Criegee, L.; Cussans, D. G.; Cvach, J.; Dagoret, S.; Dainton, J. B.; Dau, W. D.; Daum, K.; David, M.; Davis, C. L.; Delcourt, B.; De Roeck, A.; De Wolf, E. A.; Dirkmann, M.; Dixon, P.; Di Nezza, P.; Dlugosz, W.; Dollfus, C.; Dowell, J. D.; Dreis, H. B.; Droutskoi, A.; Düllmann, D.; Dünger, O.; Duhm, H.; Ebert, J.; Ebert, T. R.; Eckerlin, G.; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Eisenhandler, E.; Ellison, R. J.; Elsen, E.; Erdmann, M.; Erdmann, W.; Evrard, E.; Fahr, A. B.; Favart, L.; Fedotov, A.; Feeken, D.; Felst, R.; Feltesse, J.; Ferencei, J.; Ferrarotto, F.; Flamm, K.; Fleischer, M.; Flieser, M.; Flügge, G.; Fomenko, A.; Fominykh, B.; Formánek, J.; Foster, J. M.; Franke, G.; Fretwurst, E.; Gabathuler, E.; Gabathuler, K.; Gaede, F.; Garvey, J.; Gayler, J.; Gebauer, M.; Gellrich, A.; Genzel, H.; Gerhards, R.; Glazov, A.; Goerlach, U.; Goerlich, L.; Gogitidze, N.; Goldberg, M.; Goldner, D.; Golec-Biernat, K.; Gonzalez-Pineiro, B.; Gorelov, I.; Grab, C.; Grässler, H.; Grässler, R.; Greenshaw, T.; Griffiths, R.; Grindhammer, G.; Gruber, A.; Gruber, C.; Haack, J.; Haidt, D.; Hajduk, L.; Hampel, M.; Haynes, W. J.; Heinzelmann, G.; Henderson, R. C. W.; Henschel, H.; Herynek, I.; Hess, M. F.; Hildesheim, W.; Hiller, K. H.; Hilton, C. D.; Hladký, J.; Hoeger, K. C.; Höppner, M.; Hoffmann, D.; Holtom, T.; Horisberger, R.; Hudgson, V. L.; Hütte, M.; Hufnagel, H.; Ibbotson, M.; Itterbeck, H.; Jacholkowska, A.; Jacobsson, C.; Jaffre, M.; Janoth, J.; Jansen, T.; Jöhnson, L.; Johannsen, K.; Johnson, D. P.; Johnson, L.; Jung, H.; Kalmus, P. I. P.; Kander, M.; Kant, D.; Kaschowitz, R.; Kathage, U.; Katzy, J.; Kaufmann, H. H.; Kaufmann, O.; Kazarian, S.; Kenyon, I. R.; Kermiche, S.; Keuker, C.; Kiesling, C.; Klein, M.; Kleinwort, C.; Knies, G.; Köhler, T.; Köhne, J. H.; Kolanoski, H.; Kole, F.; Kolya, S. D.; Korbel, V.; Korn, M.; Kostka, P.; Kotelnikov, S. K.; Krämerkämper, T.; Krasny, M. W.; Krehbiel, H.; Krücker, D.; Krüger, U.; Krüner-Marquis, U.; Küster, H.; Kuhlen, M.; Kurča, T.; Kurzhöfer, J.; Lacour, D.; Laforge, B.; Lander, R.; Landon, M. P. J.; Lange, W.; Langenegger, U.; Laporte, J.-F.; Lebedev, A.; Lehner, F.; Leverenz, C.; Levonian, S.; Ley, Ch.; Lindström, G.; Lindstroem, M.; Link, J.; Linsel, F.; Lipinski, J.; List, B.; Lobo, G.; Lohmander, H.; Lomas, J. W.; Lopez, G. C.; Lubimov, V.; Lüke, D.; Magnussen, N.; Malinovski, E.; Mani, S.; Maraček, R.; Marage, P.; Marks, J.; Marshall, R.; Martens, J.; Martin, G.; Martin, R.; Martyn, H.-U.; Martyniak, J.; Mavroidis, T.; Maxfield, S. J.; McMahon, S. J.; Mehta, A.; Meier, K.; Merz, T.; Meyer, A.; Meyer, A.; Meyer, H.; Meyer, J.; Meyer, P.-O.; Migliori, A.; Mikocki, S.; Milstead, D.; Moeck, J.; Moreau, F.; Morris, J. V.; Mroczko, E.; Müller, D.; Müller, G.; Müller, K.; Murín, P.; Nagovizin, V.; Nahnhauer, R.; Naroska, B.; Naumann, Th.; Newman, P. R.; Newton, D.; Neyret, D.; Nguyen, H. K.; Nicholls, T. C.; Niebergall, F.; Niebuhr, C.; Niedzballa, Ch.; Niggli, H.; Nisius, R.; Nowak, G.; Noyes, G. W.; Nyberg-Werther, M.; Oakden, M.; Oberlack, H.; Obrock, U.; Olsson, J. E.; Ozerov, D.; Palmen, P.; Panaro, E.; Panitch, A.; Pascaud, C.; Patel, G. D.; Pawletta, H.; Peppel, E.; Perez, E.; Phillips, J. P.; Pieuchot, A.; Pitzl, D.; Pope, G.; Prell, S.; Prosi, R.; Rabbertz, K.; Rädel, G.; Raupach, F.; Reimer, P.; Reinshagen, S.; Rick, H.; Riech, V.; Riedlberger, J.; Riepenhausen, F.; Riess, S.; Rizvi, E.; Robertson, S. M.; Robmann, P.; Roloff, H. E.; Roosen, R.; Rosenbauer, K.; Rostovtsev, A.; Rouse, F.; Royon, C.; Rüter, K.; Rusakov, S.; Rybicki, K.; Sahlmann, N.; Sankey, D. P. C.; Schacht, P.; Schiek, S.; Schleif, S.; Schleper, P.; von Schlippe, W.; Schmidt, D.; Schmidt, G.; Schöning, A.; Schröder, V.; Schuhmann, E.; Schwab, B.; Sefkow, F.; Seidel, M.; Sell, R.; Semenov, A.; Shekelyan, V.; Sheviakov, I.; Shtarkov, L. N.; Siegmon, G.; Siewert, U.; Sirois, Y.; Skillicorn, I. O.; Smirnov, P.; Smith, J. R.; Solochenko, V.; Soloviev, Y.; Specka, A.; Spiekermann, J.; Spielman, S.; Spitzer, H.; Squinabol, F.; Starosta, R.; Steenbock, M.; Steffen, P.; Steinberg, R.; Steiner, H.; Stella, B.; Stellberger, A.; Stier, J.; Stiewe, J.; Stöβlein, U.; Stolze, K.; Straumann, U.; Struczinski, W.; Sutton, J. P.; Tapprogge, S.; Taševský, M.; Tchernyshov, V.; Tchetchelnitski, S.; Theissen, J.; Thiebaux, C.; Thompson, G.; Truöl, P.; Turnau, J.; Tutas, J.; Uelkes, P.; Usik, A.; Valkár, S.; Valkárová, A.; Vallée, C.; Vandenplas, D.; Van Esch, P.; Van Mechelen, P.; Vazdik, Y.; Verrecchia, P.; Villet, G.; Wacker, K.; Wagener, A.; Wagener, M.; Walther, A.; Waugh, B.; Weber, G.; Weber, M.; Wegener, D.; Wegner, A.; Wengler, T.; Werner, M.; West, L. R.; Wilksen, T.; Willard, S.; Winde, M.; Winter, G.-G.; Wittek, C.; Wünsch, E.; Žáček, J.; Zarbock, D.; Zhang, Z.; Zhokin, A.; Zimmer, M.; Zomer, F.; Zsembery, J.; Zuber, K.; zurNedden, M.; H1 Collaboration

1996-02-01

Results on J/ ψ production in ep interactions in the H1 experiment at HERA are presented. The J/ ψ mesons are produced by almost real photons ( Q2 ≈ 0) and detected via their leptonic decays. The data have been taken in 1994 and correspond to an integrated luminosity of 2.7 pb -1. The γp cross section for elastic J/ ψ production is observed to increase strongly with the center of mass energy. The cross section for diffractive J/ ψ production with proton dissociation is found to be of similar magnitude as the elastic cross section. Distributions of transverse momentum and decay angle are studied and found to be in accord with a diffractive production mechanism. For inelastic J/ ψ production the total γp cross section, the distribution of transverse momenta, and the elasticity of the J/ ψ are compared to NLO QCD calculations in a colour singlet model and agreement is found. Diffractive ψ' production has been observed and a first estimate of the ratio to J/ ψ production in the HERA energy regime is given.

Questionnaire design from a cross-cultural perspective: an empirical investigation of Koreans and non-Koreans.

PubMed

Willis, Gordon; Zahnd, Elaine

2007-11-01

A persistent challenge to self-report data across racial, ethnic, or cultural groups is the inherent difficulty of attaining cross-cultural comparability of key measures. The current research study investigated the cross-cultural functioning of health-survey questions presented to four groups: (1) Koreans who were monolingual in Korean; (2) non-Korean native speakers of English; (3) bilingual Koreans interviewed in English, and (4) bilingual Koreans interviewed in Korean. This design allowed us to include those likely to be medically underserved, and to assess both linguistic and cultural barriers to collecting health survey data. A total of 36 cognitive interviews were conducted to identify (a) translation problems; (b) problems of cultural adaptation that impede cross-cultural comparability; and (c) generic problems of questionnaire design that affect all groups. An important category of problems was identified that appeared to result from the interaction of respondent and question characteristics. Such problems can best be assessed through explicit consideration of the socio-cultural backgrounds of survey respondents, as opposed to the more usual focus on details of item translation and wording.

Exploring How White and Asian American Students Experience Cross-Racial Interactions: A Phenomenological Study

ERIC Educational Resources Information Center

Robinson, Thomas E.

2012-01-01

Interracial interactions between college students are responsible for important learning outcomes, however many colleges and universities have failed to purposefully encourage students to interact across racial backgrounds. As a result of a lack purposefully facilitated cross-racial interactions (CRIs), fewer interracial interactions occur on U.S.…

Energy and Mass-Number Dependence of Hadron-Nucleus Total Reaction Cross Sections

NASA Astrophysics Data System (ADS)

Kohama, Akihisa; Iida, Kei; Oyamatsu, Kazuhiro

2016-09-01

We thoroughly investigate how proton-nucleus total reaction cross sections depend on the target mass number A and the proton incident energy. In doing so, we systematically analyze nuclear reaction data that are sensitive to nuclear size, namely, proton-nucleus total reaction cross sections and differential elastic cross sections, using a phenomenological black-sphere approximation of nuclei that we are developing. In this framework, the radius of the black sphere is found to be a useful length scale that simultaneously accounts for the observed proton-nucleus total reaction cross section and first diffraction peak in the proton elastic differential cross section. This framework, which is shown here to be applicable to antiprotons, is expected to be applicable to any kind of projectile that is strongly attenuated in the nucleus. On the basis of a cross-section formula constructed within this framework, we find that a less familiar A1/6 dependence plays a crucial role in describing the energy dependence of proton-nucleus total reaction cross sections.

Elastic and Diffractive Scattering - Proceedings of the International Conference on Vth Blois Workshop

NASA Astrophysics Data System (ADS)

Kang, K.; Fried, H. M.; Tan, C.-I.

1994-02-01

The Table of Contents for the book is as follows: * Preface * `Overview' on Elastic Scattering and Total Cross-Sections * A Precise Measurement of the Real Part of the Elastic Scattering Amplitude at the {S bar{p}pS} * Luminosity Dependent Measurement of the p bar{p} Total Cross Section at √{s} = 541 GeV * Status of Fermilab E-710 * Luminosity-Independent Measurement of bar{p}p Elastic Scattering, Single Diffraction, Dissociation and Total Cross Section at √{s} = 546 and 1800 GeV * Phase Relations Revisited: A Challenge for SSC and LHC * Status of Near-Forward Elastic Scattering * bar{p}p Collisions at √{s} = 1.8 TeV: p, σt and B * p bar{p} Forward Scattering Parameters Results from Fermilab E760 * Photoproduction Results from H1 at HERA * Total and Jet Photoproduction Cross Sections at HERA and Fermilab * Minijet Model for High Energy γp Cross Sections * The Pomeron as Massive Gluons * Large N Theories with Glueball-like Spectra * Unitarity Relations for Gluonic Pomeron * The Donnachie-Landshoff Pomeron vs. QCD * The Odderon Intercept in Perturbative QCD * Theoret. and Phenomenol. Aspects of the Odderon * First Theorist's Gaze at HERA Data at Low xB * H1 Results for Structure Functions at Small x * Partial Photoproduction Cross Sections at √{s} ≈prox 180 GeV and First Results on F2 of the Proton from the ZEUS Experiment * Observation of a New Class of Events in Deep Inelastic Scattering * Jet Production in Muon-Proton and Muon-Nuclei Scattering at Fermilab-E665 * D0 Studies of Perturbative QCD * Large Rapidity Gaps and Single Diffraction Dissociation in High Energy pp and bar{p}p Collisions * Hadron and Reggeon Structure in High Energy Collisions * Monte Carlo Studies of Diffractive Processes in Deep Inelastic Scattering * Elastic Parton-Parton Amplitudes in Geometrical Models * Non-Perturbative QCD Calculations of High-Energy Observables * Effective Field Theory for Diffractive QCD Processes * High Energy Behavior of σtot, ρ, and B - Asymptotic Amplitude Analysis and a QCD-Inspired Analysis * Rapidity Gaps and Multiplicity Fluctuations * Branching Processes and Multi-Particle Production * High Energy Elastic Scattering and Nucleon as a Topological Soliton * The Behavior of Cross Sections at Very High Energies * The Pomeron and QCD with Many Light Quarks * Heterotic Pomeron: High Energy Hadronic Collisions in QCD * CDF Results on Electroweak Physics * DØ Results on Electroweak Physics * Search for the Top Quark and Other New Particles at DØ * Rapidity Gaps and Forward Physics at DØ * High Energy Asymptotics of Perturbative Multi-Color QCD * Rapidity Gaps in e+e- Collisions * Large Rapidity Gap, Jet Events at HERA: a PQCD Approach * High Energy Parton-Parton Elastic Scattering in QCD * Parton-Parton Elastic Scattering and Rapidity Gaps at Tevatron Energies * Hard Elastic Scattering * Hard Diffractive Processes * Three Successful Tests of Color Transparency and Nuclear Filtering * New KNO in QCD * A Chiral Condensate Search at the Tevatron * Cosmic Ray Evidences for Aligned High Energy Jets at Supertevatron Energy and Hard DDD * "New Hadronic State" Observed in Extremely High Energy Cosmic-Ray Interactions * Meson and Nucleon Form Factors in PQCD * Elastic Charge Form Factors for Pseudoscalar Mesons * The Ultimate Experiment * Search for Coherent Charm Production in 800 GeV/c Proton-Silicon Interactions * Chiral Quark Model and Hadron Scattering * Elastic Spin Experiments at UNK, Fermilab and SSC * Spin-Flip in Elastic and Diffractive Scattering * FNAL Polarized Beams and Spin Dependence at RHIC * Particle Tracking in the Close-to-Forward Region (η > 5.5) * Blois V: Experimental Summary * Blois V: Summary Talk * List of Participants

UV-SPR biosensor for biomolecular interaction studies

NASA Astrophysics Data System (ADS)

Geiss, F. A.; Fossati, S.; Khan, I.; Gisbert Quilis, N.; Knoll, W.; Dostalek, J.

2017-05-01

UV surface plasmon resonance (SPR) for direct in situ detection of protein binding events is reported. A crossed relief aluminum grating was employed for diffraction coupling to surface plasmons as an alternative to more commonly used attenuated total reflection method. Wavelength interrogation of SPR was carried out by using transmission measurements in order to probe odorant-binding protein 14 (OBP14) of the honey bee (Apis mellifera). The native oxide layer on the top of an aluminum grating sensor chip allows for covalent coupling of protein molecules by using regular silane-based linkers. The probing of bound OBP14 protein at UV with confined field of surface plasmons holds potential for further studies of interaction with recently developed artificial fluorescent odorants.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Orlenko, E. V., E-mail: eorlenko@mail.ru; Evstafev, A. V.; Orlenko, F. E.

A formalism of exchange perturbation theory (EPT) is developed for the case of interactions that explicitly depend on time. Corrections to the wave function obtained in any order of perturbation theory and represented in an invariant form include exchange contributions due to intercenter electron permutations in complex multicenter systems. For collisions of atomic systems with an arbitrary type of interaction, general expressions are obtained for the transfer (T) and scattering (S) matrices in which intercenter electron permutations between overlapping nonorthogonal states belonging to different centers (atoms) are consistently taken into account. The problem of collision of alpha particles with lithiummore » atoms accompanied by the redistribution of electrons between centers is considered. The differential and total charge-exchange cross sections of lithium are calculated.« less

Health Care Professionals' Understandings of Cross-Cultural Interaction in End-of-Life Care: A Focus Group Study.

PubMed

Milberg, Anna; Torres, Sandra; Ågård, Pernilla

2016-01-01

The academic debate on cross-cultural interaction within the context of end-of-life care takes for granted that this interaction is challenging. However, few empirical studies have actually focused on what health care professionals think about this interaction. This study aimed to explore health care professionals' understandings of cross-cultural interaction during end-of-life care. Sixty end-of-life care professionals were recruited from eleven care units in Sweden to take part in focus group interviews. These interviews were analyzed using qualitative content analysis. The health care professionals interviewed talked about cross-cultural interaction in end-of-life care as interaction that brings about uncertainty, stress and frustration even though they had limited experience of this type of interaction. The focus group discussions brought attention to four specific challenges that they expected to meet when they care for patients with migrant backgrounds since they took for granted that they would have an ethno-cultural background that is different to their own. These challenges had to do with communication barriers, 'unusual' emotional and pain expressions, the expectation that these patients' families would be 'different' and the anticipation that these patients and their families lack knowledge. At the core of the challenges in question is the idea that cross-cultural interaction means meeting "the unknown". In addition, the end-of-life care professionals interviewed talked about patients whose backgrounds they did not share in homogenizing terms. It is against this backdrop that they worried about their ability to provide end-of-life care that is individualized enough to meet the needs of these patients. The study suggests that end-of-life care professionals who regard cross-cultural interaction in this manner could face actual challenges when caring for patients whose backgrounds they regard as "the unknown" since they anticipate a variety of challenges and do not seem confident enough that they can provide good quality care when cross-cultural interaction is at stake.

Total cross sections ν μ and ḡn μcharged-current interactions between 20 and 200 GeV

NASA Astrophysics Data System (ADS)

Bosetti, P.; Deden, H.; Fritze, P.; Grässler, H.; Hasert, F. J.; Schulte, R.; Böckmann, K.; Kokott, Th.; Nellen, B.; Wünsch, B.; Cundy, D. C.; Grant, A.; Hulth, P. O.; Klein, H.; Morrison, D. R. O.; Pagiola, E.; Pape, L.; Peyrou, Ch.; Scott, W. G.; Wachsmuth, H.; Simopoulou, E.; Vayaki, A.; Barnham, K. W. J.; Butterworth, I.; Iaselli, G.; Miller, D. B.; Mobayyen, M.; Penfold, C.; Petrides, A.; Powell, K. J.; Albajar, C.; Perkins, D. H.; Radojicic, D.; Saitta, B.; Bolognese, T.; Tallini, B.; Velasco, J.; Vignaud, D.; Aachen-Bonn-Cern-Demokritos-London-Oxford-Saclay Collaboration

1982-03-01

Exposures of the Ne/H 2 filled Big European Bubble Chamber (BEBC) to a dichromatic neutrino (antineutrino) beam produced by 400 GeV protons of the CERN SPS yielded ∼ 3100 events with a negative, and ∼ 1100 with a positive, muon. The neutrino flux is determined from the muon flux in the shielding. Assuming a linear energy dependence of the cross section, the values {σ}/{E} between 20 and 200 GeV are found to be 0.657 ± 0.012 (stat.) ± 0.027 (syst.) and 0.309 ± 0.009 (stat.) ± 0.013 (syst.) cm 2 (GeV nucleon) -1, for neutrinos and antineutrinos, respectively. The scaling variable {q 2}/{E} decreases significantly with increasing energy both for neutrinos and antineutrinos.

Interactions between physicians and pharmaceutical sales representatives in Saudi Arabia.

PubMed

Alosaimi, Fahad Dakheel; Alkaabba, Abdulaziz; Qadi, Mahdi; Albahlal, Abdullah; Alabdulkarim, Yasir; Alabduljabbar, Mohammad; Alqahtani, Faisal

2013-01-01

Interaction between physicians and pharmaceutical sales representative (PR) is a major component of the promotional activities by pharmaceutical companies. The lack of studies examining the magnitude of this interaction in Saudi Arabia is evident. The objective of this study is to estimate the magnitude and associated characteristics of physician-PR interaction. A cross-sectional study was conducted among physicians working in the different regions of Saudi Arabia between March and July of 2012. A cross-sectional study was undertaken between March and July of 2012 in the different regions of Saudi Arabia. A self-administrated questionnaire was developed and handed to all participants, both in paper and electronic formats. A total of 663 participants completed the questionnaire. The participation rate was 66.3% (663/1000). The majority of the participants (72.9%) reported interaction with PRs. This was lower among residents/interns compared to higher ranking employees (55.6% vs 83.6%, P < .001). Approximately half (48.3%) of the interactions occurred at a rate of more than once a month. A majority of the participants (72.1%) occasionally accepted gifts such as stationery (57%), drug samples (54%), meals (38%), and sponsorship of educational activities (30%). The following characteristics were independently associated with physician-PR interaction: non-Saudi nationals, a higher monthly income, Western medical education, working in a private hospital, being a specialist or registrar (rather than resident or intern), working on certain specialties (such as psychiatry and family medicine), and having limited number of patients with high socioeconomic status. Although lower than seen in many parts of the world, a high prevalence of physician-PR inter.action in Saudi hospitals is reported. Delineating associated characteristics may assist with future interventions. Further research should focus on ethical, clinical, prescription, and economic impact of interaction as well as determining the best strategy to reduce negative impact.

Mitigation of cross-beam energy transfer in symmetric implosions on OMEGA using wavelength detuning

DOE PAGES

Edgell, D. H.; Follett, R. K.; Igumenshchev, I. V.; ...

2017-06-13

The effects of frequency detuning laser beams in direct-drive symmetric implosions were investigated with a 3-D cross-beam energy transfer (CBET) model. Our model shows that interactions between beams with relative angles between 45° and 90° are most significant for CBET in OMEGA direct-drive implosions. There is no net exchange in power between beams but there is significant redistribution of power from the ingoing central portion of the beam profile to the outgoing edge as it is exiting the plasma, reducing the total absorbed power. Furthermore, redistribution of laser power because of CBET increases the root-mean-square (rms) absorption nonuniformity by anmore » order of magnitude. CBET mitigation by shifting relative wavelengths of three groups of laser beams fed by each of the different beamlines was modeled. At an on-target wavelength shift of Δλ ~ 10 Å, the total laser absorption was maximized, and the rms absorption nonuniformity was near minimum. In order to completely decouple the three groups of beams from each other requires wavelength shifts Δλ > 30 Å.« less

Mitigation of cross-beam energy transfer in symmetric implosions on OMEGA using wavelength detuning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Edgell, D. H.; Follett, R. K.; Igumenshchev, I. V.

The effects of frequency detuning laser beams in direct-drive symmetric implosions were investigated with a 3-D cross-beam energy transfer (CBET) model. Our model shows that interactions between beams with relative angles between 45° and 90° are most significant for CBET in OMEGA direct-drive implosions. There is no net exchange in power between beams but there is significant redistribution of power from the ingoing central portion of the beam profile to the outgoing edge as it is exiting the plasma, reducing the total absorbed power. Furthermore, redistribution of laser power because of CBET increases the root-mean-square (rms) absorption nonuniformity by anmore » order of magnitude. CBET mitigation by shifting relative wavelengths of three groups of laser beams fed by each of the different beamlines was modeled. At an on-target wavelength shift of Δλ ~ 10 Å, the total laser absorption was maximized, and the rms absorption nonuniformity was near minimum. In order to completely decouple the three groups of beams from each other requires wavelength shifts Δλ > 30 Å.« less

The physics of solid-state neutron detector materials and geometries.

PubMed

Caruso, A N

2010-11-10

Detection of neutrons, at high total efficiency, with greater resolution in kinetic energy, time and/or real-space position, is fundamental to the advance of subfields within nuclear medicine, high-energy physics, non-proliferation of special nuclear materials, astrophysics, structural biology and chemistry, magnetism and nuclear energy. Clever indirect-conversion geometries, interaction/transport calculations and modern processing methods for silicon and gallium arsenide allow for the realization of moderate- to high-efficiency neutron detectors as a result of low defect concentrations, tuned reaction product ranges, enhanced effective omnidirectional cross sections and reduced electron-hole pair recombination from more physically abrupt and electronically engineered interfaces. Conversely, semiconductors with high neutron cross sections and unique transduction mechanisms capable of achieving very high total efficiency are gaining greater recognition despite the relative immaturity of their growth, lithographic processing and electronic structure understanding. This review focuses on advances and challenges in charged-particle-based device geometries, materials and associated mechanisms for direct and indirect transduction of thermal to fast neutrons within the context of application. Calorimetry- and radioluminescence-based intermediate processes in the solid state are not included.

Partial-wave analysis for positronium-xenon collisions in the ultralow-energy region

NASA Astrophysics Data System (ADS)

Shibuya, Kengo; Saito, Haruo

2018-05-01

We propose a method to convert measured positronium annihilation rates in gaseous xenon into total and differential cross sections of positronium-xenon collisions in an ultralow-energy region of less than 80 meV where their experimental determinations as functions of the positronium kinetic energy are extremely difficult. This method makes it possible to determine not only the s -wave collisional parameters but also the p -wave and d -wave parameters. We have found a small positive value of the scattering length, A0=2.06 ±0.10 a0 , which indicates that the positronium-xenon interaction in this energy region is repulsive and suggests that it is dominated by the scattering amplitude of the positron rather than that of the electron. An extrapolation of the analytical result into the experimentally inaccessible energy regions from 80 meV to 1.0 eV indicates that there should not be a Ramsauer-Townsend minimum but rather a peak in the total cross section at an energy of approximately 0.4 eV.

Space shuttle orbiter rear mounted reaction control system jet interaction study. [hypersonic wind tunnel tests

NASA Technical Reports Server (NTRS)

Rausch, J. R.

1977-01-01

The effect of interaction between the reaction control system (RCS) jets and the flow over the space shuttle orbiter in the atmosphere was investigated in the NASA Langley 31-inch continuous flow hypersonic tunnel at a nominal Mach number of 10.3 and in the AEDC continuous flow hypersonic tunnel B at a nominal Mach number of 6, using 0.01 and .0125 scale force models with aft RCS nozzles mounted both on the model and on the sting of the force model balance. The data show that RCS nozzle exit momentum ratio is the primary correlating parameter for effects where the plume impinges on an adjacent surface and mass flow ratio is the parameter when the plume interaction is primarily with the external stream. An analytic model of aft mounted RCS units was developed in which the total reaction control moments are the sum of thrust, impingement, interaction, and cross-coupling terms.

Effects of anisotropic electron-ion interactions in atomic photoelectron angular distributions

NASA Technical Reports Server (NTRS)

Dill, D.; Starace, A. F.; Manson, S. T.

1974-01-01

The photoelectron asymmetry parameter beta in LS-coupling is obtained as an expansion into contributions from alternative angular momentum transfers j sub t. The physical significance of this expansion of beta is shown to be that: (1) the electric dipole interaction transfers to the atom a charcteristic single angular momentum j sub t = sub o, where sub o is the photoelectron's initial orbital momentum; and (2) angular momentum transfers indicate the presence of anisotropic interaction of the outgoing photoelectron with the residual ion. For open shell atoms the photoelectron-ion interaction is generally anisotropic; photoelectron phase shifts and electric dipole matrix elements depend on both the multiplet term of the residual ion and the total orbital momentum of the ion-photoelectron final state channel. Consequently beta depends on the term levels of the residual ion and contains contributions from all allowed values of j sub t. Numerical calculations of the asymmetry parameters and partial cross sections for photoionization of atomic sulfur are presented.

Perception of medical undergraduate students about interactive lectures in an outcome-based integrated curriculum: A cross-sectional study

PubMed Central

Asad, Mohammad Rehan; Amir, Khwaja; Tadvi, Naser Ashraf; Afzal, Kamran; Sami, Waqas; Irfan, Abdul

2017-01-01

OBJECTIVE: The objective of this study is to explore the student's perspectives toward the interactive lectures as a teaching and learning method in an integrated curriculum. MATERIALS AND METHODS: This cross-sectional study was conducted among 1st, 2nd and 3rd year male medical students (n = 121). A self-administered questionnaire based on the Visual, Auditory, Reader, Kinesthetic learning styles, learning theories, and role of feedback in teaching and learning on five-point Likert rating scale was used. The questionnaire was constructed after extensive literature review. RESULTS: There was an 80% response rate in this study. The total number of undergraduate medical students responded in the study were n = 97, 34 students of 1st year, n = 30 students of 2nd year and n = 33 student were in 3rd year, the mean scores of the student responses were calculated using Independent samples Kruskal–Wallis. There was no significant difference in the responses of the students of different years except for the question “The Interactive lectures facilitate effective use of learning resources.” Which showed significant difference in the responses of the 3 years students by Independent samples Kruskal–Wallis test. No significant association was found between the year of study and items of the questionnaire except for the same item, “ The Interactive lectures facilitates effective use of learning resources” by Spearman rank correlation test. CONCLUSION: The students perceive interactive lecture as an effective tool for facilitating visual and auditory learning modes, and for achieving curricular strategies. The student find the feedback given during the interactive lectures is effective in modifying learning attitude and enhancing motivation toward learning. PMID:29296601

Perception of medical undergraduate students about interactive lectures in an outcome-based integrated curriculum: A cross-sectional study.

PubMed

Asad, Mohammad Rehan; Amir, Khwaja; Tadvi, Naser Ashraf; Afzal, Kamran; Sami, Waqas; Irfan, Abdul

2017-01-01

The objective of this study is to explore the student's perspectives toward the interactive lectures as a teaching and learning method in an integrated curriculum. This cross-sectional study was conducted among 1 st , 2 nd and 3 rd year male medical students ( n = 121). A self-administered questionnaire based on the Visual, Auditory, Reader, Kinesthetic learning styles, learning theories, and role of feedback in teaching and learning on five-point Likert rating scale was used. The questionnaire was constructed after extensive literature review. There was an 80% response rate in this study. The total number of undergraduate medical students responded in the study were n = 97, 34 students of 1 st year, n = 30 students of 2 nd year and n = 33 student were in 3 rd year, the mean scores of the student responses were calculated using Independent samples Kruskal-Wallis. There was no significant difference in the responses of the students of different years except for the question "The Interactive lectures facilitate effective use of learning resources." Which showed significant difference in the responses of the 3 years students by Independent samples Kruskal-Wallis test. No significant association was found between the year of study and items of the questionnaire except for the same item, " The Interactive lectures facilitates effective use of learning resources" by Spearman rank correlation test. The students perceive interactive lecture as an effective tool for facilitating visual and auditory learning modes, and for achieving curricular strategies. The student find the feedback given during the interactive lectures is effective in modifying learning attitude and enhancing motivation toward learning.

A study of photon interaction in some hormones

NASA Astrophysics Data System (ADS)

Manjunatha, H. C.

2013-05-01

The effective atomic numbers (Z eff) and electron density (N el) of some hormones such as testosterone, methandienone, estradiol and rogesterone for total and partial photon interactions have been computed in the wide energy region 1 keV-100 GeV using an accurate database of photon-interaction cross sections and the WinXCom program. The computed Z eff and N el are compared with the values generated by XMuDat program. The computer tomography (CT) numbers and kerma values relative to air are also calculated and the computed data of CT numbers in the low-energy region help in visualizing the image of the biological samples and to obtain precise accuracy in treating the inhomogenity of them in medical radiology. In view of dosimetric interest, the photon absorbed dose rates of some commonly used gamma sources (Na-21, Cs-137, Mn-52, Co-60 and Na-22) are also estimated.

Calculation of the Coulomb Fission Cross Sections for Pb-Pb and Bi-Pb Interactions at 158 A GeV

NASA Technical Reports Server (NTRS)

Poyser, William J.; Ahern, Sean C.; Norbury, John W.; Tripathi, R. K.

2002-01-01

The Weizsacker-Williams (WW) method of virtual quanta is used to make approximate cross section calculations for peripheral relativistic heavy-ion collisions. We calculated the Coulomb fission cross sections for projectile ions of Pb-208 and Bi-209 with energies of 158 A GeV interacting with a Pb-208 target. We also calculated the electromagnetic absorption cross section for Pb-208 ion interacting as described. For comparison we use both the full WW method and a standard approximate WW method. The approximate WW method in larger cross sections compared to the more accurate full WW method.

Observations of Traveling Crossflow Resonant Triad Interactions on a Swept Wing

NASA Technical Reports Server (NTRS)

Eppink, Jenna L.; Wlezien, Richard

2012-01-01

Experimental evidence indicates the presence of a triad resonance interaction between traveling crossflow modes in a swept wing flow. Results indicate that this interaction occurs when the stationary and traveling crossflow modes have similar and relatively low amplitudes (approx.1% to 6% of the total freestream velocity). The resonant interaction occurs at instability amplitudes well below those typically known to cause transition, yet transition is observed to occur just downstream of the resonance. In each case, two primary linearly unstable traveling crossflow modes are nonlinearly coupled to a higher frequency linearly stable mode at the sum of their frequencies. The higher-frequency mode is linearly stable and presumed to exist as a consequence of the interaction of the two primary modes. Autoand cross-bicoherence are used to determine the extent of phase-matching between the modes, and wavenumber matching confirms the triad resonant nature of the interaction. The bicoherence results indicate a spectral broadening mechanism and the potential path to early transition. The implications for laminar flow control in swept wing flows are significant. Even if stationary crossflow modes remain subcritical, traveling crossflow interactions can lead to early transition.

Potential drug interactions in patients given antiretroviral therapy

PubMed Central

dos Santos, Wendel Mombaque; Secoli, Silvia Regina; Padoin, Stela Maris de Mello

2016-01-01

ABSTRACT Objective: to investigate potential drug-drug interactions (PDDI) in patients with HIV infection on antiretroviral therapy. Methods: a cross-sectional study was conducted on 161 adults with HIV infection. Clinical, socio demographic, and antiretroviral treatment data were collected. To analyze the potential drug interactions, we used the software Micromedex(r). Statistical analysis was performed by binary logistic regression, with a p-value of ≤0.05 considered statistically significant. Results: of the participants, 52.2% were exposed to potential drug-drug interactions. In total, there were 218 potential drug-drug interactions, of which 79.8% occurred between drugs used for antiretroviral therapy. There was an association between the use of five or more medications and potential drug-drug interactions (p = 0.000) and between the time period of antiretroviral therapy being over six years and potential drug-drug interactions (p < 0.00). The clinical impact was prevalent sedation and cardiotoxicity. Conclusions: the PDDI identified in this study of moderate and higher severity are events that not only affect the therapeutic response leading to toxicity in the central nervous and cardiovascular systems, but also can interfere in tests used for detection of HIV resistance to antiretroviral drugs. PMID:27878224

Nuclear annihilation by antinucleons

DOE PAGES

Lee, Teck-Ghee; Wong, Cheuk-Yin

2016-01-25

We examine the momentum dependence ofmore » $$\\bar{p}$$p and $$\\bar{n}$$p annihilation cross sections by considering the transmission through a nuclear potential and the $$\\bar {p}$$p Coulomb interaction. Compared to the $$\\bar{n}$$p annihilation cross section, the $$\\bar{p}$$p annihilation cross section is significantly enhanced by the Coulomb interaction for projectile momenta below p lab < 500 MeV/c, and the two annihilation cross sections approach the Pomeranchuk's equality limit [JETP 30, 423 (1956)] at p lab ~500 MeV/c. Using these elementary cross sections as the basic input data, the extended Glauber model is employed to evaluate the annihilation cross sections for $$\\bar{n}$$ and $$\\bar{p}$$ interaction with nuclei and the results compare well with experimental data.« less

Associations of Abdominal Muscle Area with 4-Year Change in Coronary Artery Calcium Differ by Ethnicity Among Post-Menopausal Women.

PubMed

Wassel, Christina L; Laughlin, Gail A; Saad, Sarah D; Araneta, Maria Rosario G; Wooten, Wilma; Barrett-Connor, Elizabeth; Allison, Matthew A

2015-11-05

To examine the association of abdominal muscle area with coronary artery calcium (CAC) presence, extent, and progression in a multi-ethnic cohort of older, community-dwelling post-menopausal women. Cross-sectional and longitudinal population-based cohort. The sample comprised 179 non-Hispanic White women, 116 Filipina women and 144 African American women, all without known CVD, who underwent chest and abdominal computed tomography (CT) scans twice about four years apart for abdominal muscle and fat, as well as CAC. CAC presence, extent and progression. There was a significant interaction of ethnicity with baseline oblique muscle area (p-for-interaction .01), and marginally significant interactions with baseline total and paraspinal muscle for change in CAC (p-for-interactions both .09). Among Filipina women, each standard deviation (SD) greater total muscle area was associated with a 26% (95% CI (-43%, -4%), P=.02) reduced rate of change in CAC; higher paraspinal and oblique muscle area were associated with a 24% (-38%, -6%, P=.01) and a 37% (-53%, -16%, P=.0002) reduced rate of change in CAC, respectively. These associations were not significant in African American or non-Hispanic White women. There were no significant associations of abdominal muscle with CAC presence or extent, nor were there significant ethnicity by muscle interactions in these models. Among Filipina women, greater abdominal muscle mass is associated with a decreased rate of CAC progression. Higher muscle mass may be important for this group in reducing CVD outcomes.

From the γ γ →p p ¯ reaction to the production of p p ¯ pairs in ultraperipheral ultrarelativistic heavy-ion collisions at the LHC

NASA Astrophysics Data System (ADS)

Kłusek-Gawenda, Mariola; Lebiedowicz, Piotr; Nachtmann, Otto; Szczurek, Antoni

2017-11-01

In this paper we consider the production of proton-antiproton pairs in two-photon interactions in electron-positron and heavy-ion collisions. We try to understand the dependence of the total cross section on the photon-photon c.m. energy as well as corresponding angular distributions measured by the Belle Collaboration for the γ γ →p p ¯ process. To understand the Belle data we include the proton-exchange, the f2(1270 ) and f2(1950 ) s -channel exchanges, as well as the hand-bag mechanism. The helicity amplitudes for the γ γ →f2→p p ¯ process are written explicitly based on a Lagrangian approach. The parameters of vertex form factors are adjusted to the Belle data. Having described the angular distributions for the γ γ →p p ¯ process we present first predictions for the ultraperipheral, ultrarelativistic, heavy-ion reaction P208bP208b→P208bP208bp p ¯ . Both, the total cross section and several differential distributions for experimental cuts corresponding to the ALICE, ATLAS, CMS, and LHCb experiments are presented. We find the total cross section 100 μ b for the ALICE cuts, 160 μ b for the ATLAS cuts, 500 μ b for the CMS cuts, and 104 μ b taking into account the LHCb cuts. This opens a possibility to study the γ γ →p p ¯ process at the LHC.

Heavy ion fragmentation experiments at the bevatron

NASA Technical Reports Server (NTRS)

Heckman, H. H.

1976-01-01

Collaborative research efforts to study the fragmentation processes of heavy nuclei in matter using heavy ion beams of the Bevatron/Bevalac are described. The goal of the program is to obtain the single particle inclusive spectra of secondary nuclei produced at 0 deg by the fragmentation of heavy ion beam projectiles. The process being examined is B+T yields F + anything, where B is the beam nucleus, T is the target nucleus, and F is the detected fragment. The fragments F are isotopically identified by experimental procedures involving magnetic analysis, energy loss and time-of-flight measurements. Effects were also made to: (a) study processes of heavy nuclei in matter, (b) measure the total and partial production cross section for all isotopes, (c) test the applicability of high energy multiparticle interaction theory to nuclear fragmentation, (d) apply the cross section data and fragmentation probabilities to cosmic ray transport theory, and (e) search for systematic behavior of fragment production as a means to improve existing semi-empirical theories of cross-sections.

Exotic superconductivity with enhanced energy scales in materials with three band crossings

NASA Astrophysics Data System (ADS)

Lin, Yu-Ping; Nandkishore, Rahul M.

2018-04-01

Three band crossings can arise in three-dimensional quantum materials with certain space group symmetries. The low energy Hamiltonian supports spin one fermions and a flat band. We study the pairing problem in this setting. We write down a minimal BCS Hamiltonian and decompose it into spin-orbit coupled irreducible pairing channels. We then solve the resulting gap equations in channels with zero total angular momentum. We find that in the s-wave spin singlet channel (and also in an unusual d-wave `spin quintet' channel), superconductivity is enormously enhanced, with a possibility for the critical temperature to be linear in interaction strength. Meanwhile, in the p-wave spin triplet channel, the superconductivity exhibits features of conventional BCS theory due to the absence of flat band pairing. Three band crossings thus represent an exciting new platform for realizing exotic superconducting states with enhanced energy scales. We also discuss the effects of doping, nonzero temperature, and of retaining additional terms in the k .p expansion of the Hamiltonian.

Effective Cross Section of Cold Formed Steel Column Under Axial Compression

NASA Astrophysics Data System (ADS)

Manikandan, P.; Pradeep, T.

2018-06-01

The compressive resistance of cold-formed steel (CFS) section may be governed by local, distortional or overall buckling and any apparent interaction between these modes. A new inventive stiffened CFS section is elected in this study, selected cross sections geometries and lengths are chosen such that all the types of buckling modes are met with. Buckling plot is plotted using linear elastic buckling analysis software (CUFSM). Using the test results obtained in the literature, the developed finite element model is calibrated and furthers a total of 126 parametric study is conducted such as a consequence of dimensions and the length of the cross section, thickness and yield stress. The FEA included relevant material and geometric imperfections. All the columns are analyzed under pin end conditions with axial compression. The analysis results demonstrate that the DSM equations generally assess the strength of stiffened section conservatively. Modifications to the DSM equations are recommended to evaluate the strength of stiffened section more precisely.

A new time of flight mass spectrometer for absolute dissociative electron attachment cross-section measurements in gas phase

NASA Astrophysics Data System (ADS)

Chakraborty, Dipayan; Nag, Pamir; Nandi, Dhananjay

2018-02-01

A new time of flight mass spectrometer (TOFMS) has been developed to study the absolute dissociative electron attachment (DEA) cross section using a relative flow technique of a wide variety of molecules in gas phase, ranging from simple diatomic to complex biomolecules. Unlike the Wiley-McLaren type TOFMS, here the total ion collection condition has been achieved without compromising the mass resolution by introducing a field free drift region after the lensing arrangement. The field free interaction region is provided for low energy electron molecule collision studies. The spectrometer can be used to study a wide range of masses (H- ion to few hundreds atomic mass unit). The mass resolution capability of the spectrometer has been checked experimentally by measuring the mass spectra of fragment anions arising from DEA to methanol. Overall performance of the spectrometer has been tested by measuring the absolute DEA cross section of the ground state SO2 molecule, and the results are satisfactory.

Comparative mapping of quantitative trait loci for tassel-related traits of maize in F2:3 and RIL populations.

PubMed

Yi, Qiang; Liu, Yinghong; Zhang, Xiangge; Hou, Xianbin; Zhang, Junjie; Liu, Hanmei; Hu, Yufeng; Yu, Guowu; Huang, Yubi

2018-03-01

Tassel architecture is an important trait in maize breeding and hybrid seed production. In this study, we investigated total tassel length (TTL) and tassel branch number (TBN) in 266 F 2:3 families across six environments and in 301 recombinant inbred lines (RILs) across three environments, where all the plants were derived from a cross between 08-641 and Ye478. We compared the genetic architecture of the two traits across two generations through combined analysis. In total, 27 quantitative trait loci (QTLs) (15 in F 2:3 ; 16 in RIL), two QTL × environment interactions (both in F 2:3 ), 11 pairs of epistatic interactions (seven in F 2:3 ; four in RIL) and four stable QTLs in both the F 2:3 and RILs were detected. The RIL population had higher detection power than the F 2:3 population. Nevertheless, QTL × environment interactions and epistatic interactions could be more easily detected in the F 2:3 population than in the RILs. Overall, the QTL mapping results in the F 2:3 and RILs were greatly influenced by genetic generations and environments. Finally, fine mapping for a novel and major QTL, qTTL-2-3 (bin 2.07), which accounted for over 8.49% of the phenotypic variation across different environments and generations, could be useful in marker-assisted breeding.

Coherent J/ψ photoproduction in ultra-peripheral PbPb collisions at √{sNN} = 2.76TeV with the CMS experiment

NASA Astrophysics Data System (ADS)

Khachatryan, V.; Sirunyan, A. M.; Tumasyan, A.; Adam, W.; Asilar, E.; Bergauer, T.; Brandstetter, J.; Brondolin, E.; Dragicevic, M.; Erö, J.; Flechl, M.; Friedl, M.; Frühwirth, R.; Ghete, V. M.; Hartl, C.; Hörmann, N.; Hrubec, J.; Jeitler, M.; König, A.; Krammer, M.; Krätschmer, I.; Liko, D.; Matsushita, T.; Mikulec, I.; Rabady, D.; Rad, N.; Rahbaran, B.; Rohringer, H.; Schieck, J.; Schöfbeck, R.; Strauss, J.; Treberer-Treberspurg, W.; Waltenberger, W.; Wulz, C.-E.; Mossolov, V.; Shumeiko, N.; Suarez Gonzalez, J.; Alderweireldt, S.; Cornelis, T.; De Wolf, E. A.; Janssen, X.; Knutsson, A.; Lauwers, J.; Luyckx, S.; Van De Klundert, M.; Van Haevermaet, H.; Van Mechelen, P.; Van Remortel, N.; Van Spilbeeck, A.; Abu Zeid, S.; Blekman, F.; D'Hondt, J.; Daci, N.; De Bruyn, I.; Deroover, K.; Heracleous, N.; Keaveney, J.; Lowette, S.; Moortgat, S.; Moreels, L.; Olbrechts, A.; Python, Q.; Strom, D.; Tavernier, S.; Van Doninck, W.; Van Mulders, P.; Van Onsem, G. P.; Van Parijs, I.; Brun, H.; Caillol, C.; Clerbaux, B.; De Lentdecker, G.; Fasanella, G.; Favart, L.; Goldouzian, R.; Grebenyuk, A.; Karapostoli, G.; Lenzi, T.; Léonard, A.; Maerschalk, T.; Marinov, A.; Perniè, L.; Randle-conde, A.; Seva, T.; Vander Velde, C.; Vanlaer, P.; Yonamine, R.; Zenoni, F.; Zhang, F.; Benucci, L.; Cimmino, A.; Crucy, S.; Dobur, D.; Fagot, A.; Garcia, G.; Gul, M.; Mccartin, J.; Ocampo Rios, A. A.; Poyraz, D.; Ryckbosch, D.; Salva, S.; Sigamani, M.; Tytgat, M.; Van Driessche, W.; Yazgan, E.; Zaganidis, N.; Basegmez, S.; Beluffi, C.; Bondu, O.; Brochet, S.; Bruno, G.; Caudron, A.; Ceard, L.; De Visscher, S.; Delaere, C.; Delcourt, M.; Favart, D.; Forthomme, L.; Giammanco, A.; Jafari, A.; Jez, P.; Komm, M.; Lemaitre, V.; Mertens, A.; Musich, M.; Nuttens, C.; Perrini, L.; Piotrzkowski, K.; Quertenmont, L.; Selvaggi, M.; Vidal Marono, M.; Beliy, N.; Hammad, G. H.; Aldá, W. L.; Alves, F. L.; Alves, G. A.; Brito, L.; Correa Martins, M.; Hamer, M.; Hensel, C.; Moraes, A.; Pol, M. E.; Rebello Teles, P.; Belchior Batista Das Chagas, E.; Carvalho, W.; Chinellato, J.; Custódio, A.; Da Costa, E. M.; De Jesus Damiao, D.; De Oliveira Martins, C.; Fonseca De Souza, S.; Huertas Guativa, L. M.; Malbouisson, H.; Matos Figueiredo, D.; Mora Herrera, C.; Mundim, L.; Nogima, H.; Prado Da Silva, W. L.; Santoro, A.; Sznajder, A.; Tonelli Manganote, E. J.; Vilela Pereira, A.; Ahuja, S.; Bernardes, C. A.; De Souza Santos, A.; Dogra, S.; Fernandez Perez Tomei, T. R.; Gregores, E. M.; Mercadante, P. G.; Moon, C. S.; Novaes, S. F.; Padula, Sandra S.; Romero Abad, D.; Ruiz Vargas, J. C.; Aleksandrov, A.; Hadjiiska, R.; Iaydjiev, P.; Rodozov, M.; Stoykova, S.; Sultanov, G.; Vutova, M.; Dimitrov, A.; Glushkov, I.; Litov, L.; Pavlov, B.; Petkov, P.; Fang, W.; Ahmad, M.; Bian, J. G.; Chen, G. M.; Chen, H. S.; Chen, M.; Cheng, T.; Du, R.; Jiang, C. H.; Leggat, D.; Plestina, R.; Romeo, F.; Shaheen, S. M.; Spiezia, A.; Tao, J.; Wang, C.; Wang, Z.; Zhang, H.; Asawatangtrakuldee, C.; Ban, Y.; Li, Q.; Liu, S.; Mao, Y.; Qian, S. J.; Wang, D.; Xu, Z.; Avila, C.; Cabrera, A.; Chaparro Sierra, L. F.; Florez, C.; Gomez, J. P.; Gomez Moreno, B.; Sanabria, J. C.; Godinovic, N.; Lelas, D.; Puljak, I.; Ribeiro Cipriano, P. M.; Antunovic, Z.; Kovac, M.; Brigljevic, V.; Kadija, K.; Luetic, J.; Micanovic, S.; Sudic, L.; Attikis, A.; Mavromanolakis, G.; Mousa, J.; Nicolaou, C.; Ptochos, F.; Razis, P. A.; Rykaczewski, H.; Finger, M.; Finger, M.; Awad, A.; Elgammal, S.; Mohamed, A.; Salama, E.; Calpas, B.; Kadastik, M.; Murumaa, M.; Raidal, M.; Tiko, A.; Veelken, C.; Eerola, P.; Pekkanen, J.; Voutilainen, M.; Härkönen, J.; Karimäki, V.; Kinnunen, R.; Lampén, T.; Lassila-Perini, K.; Lehti, S.; Lindén, T.; Luukka, P.; Peltola, T.; Tuominiemi, J.; Tuovinen, E.; Wendland, L.; Talvitie, J.; Tuuva, T.; Besancon, M.; Couderc, F.; Dejardin, M.; Denegri, D.; Fabbro, B.; Faure, J. L.; Favaro, C.; Ferri, F.; Ganjour, S.; Givernaud, A.; Gras, P.; Hamel de Monchenault, G.; Jarry, P.; Locci, E.; Machet, M.; Malcles, J.; Rander, J.; Rosowsky, A.; Titov, M.; Zghiche, A.; Abdulsalam, A.; Antropov, I.; Baffioni, S.; Beaudette, F.; Busson, P.; Cadamuro, L.; Chapon, E.; Charlot, C.; Davignon, O.; Filipovic, N.; Granier de Cassagnac, R.; Jo, M.; Lisniak, S.; Miné, P.; Naranjo, I. N.; Nguyen, M.; Ochando, C.; Ortona, G.; Paganini, P.; Pigard, P.; Regnard, S.; Salerno, R.; Sirois, Y.; Strebler, T.; Yilmaz, Y.; Zabi, A.; Agram, J.-L.; Andrea, J.; Aubin, A.; Bloch, D.; Brom, J.-M.; Buttignol, M.; Chabert, E. C.; Chanon, N.; Collard, C.; Conte, E.; Coubez, X.; Fontaine, J.-C.; Gelé, D.; Goerlach, U.; Goetzmann, C.; Le Bihan, A.-C.; Merlin, J. A.; Skovpen, K.; Van Hove, P.; Gadrat, S.; Beauceron, S.; Bernet, C.; Boudoul, G.; Bouvier, E.; Carrillo Montoya, C. 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M.; Pistone, C.; Pooth, O.; Stahl, A.; Aldaya Martin, M.; Asin, I.; Bartosik, N.; Beernaert, K.; Behnke, O.; Behrens, U.; Borras, K.; Burgmeier, A.; Campbell, A.; Contreras-Campana, C.; Costanza, F.; Diez Pardos, C.; Dolinska, G.; Dooling, S.; Eckerlin, G.; Eckstein, D.; Eichhorn, T.; Gallo, E.; Garay Garcia, J.; Geiser, A.; Gizhko, A.; Gunnellini, P.; Hauk, J.; Hempel, M.; Jung, H.; Kalogeropoulos, A.; Karacheban, O.; Kasemann, M.; Katsas, P.; Kieseler, J.; Kleinwort, C.; Korol, I.; Lange, W.; Leonard, J.; Lipka, K.; Lobanov, A.; Lohmann, W.; Mankel, R.; Melzer-Pellmann, I.-A.; Meyer, A. B.; Mittag, G.; Mnich, J.; Mussgiller, A.; Nayak, A.; Ntomari, E.; Pitzl, D.; Placakyte, R.; Raspereza, A.; Roland, B.; Sahin, M. Ö.; Saxena, P.; Schoerner-Sadenius, T.; Seitz, C.; Spannagel, S.; Stefaniuk, N.; Trippkewitz, K. D.; Walsh, R.; Wissing, C.; Blobel, V.; Centis Vignali, M.; Draeger, A. R.; Dreyer, T.; Erfle, J.; Garutti, E.; Goebel, K.; Gonzalez, D.; Görner, M.; Haller, J.; Hoffmann, M.; Höing, R. S.; Junkes, A.; Klanner, R.; Kogler, R.; Kovalchuk, N.; Lapsien, T.; Lenz, T.; Marchesini, I.; Marconi, D.; Meyer, M.; Niedziela, M.; Nowatschin, D.; Ott, J.; Pantaleo, F.; Peiffer, T.; Perieanu, A.; Pietsch, N.; Poehlsen, J.; Sander, C.; Scharf, C.; Schleper, P.; Schlieckau, E.; Schmidt, A.; Schumann, S.; Schwandt, J.; Sola, V.; Stadie, H.; Steinbrück, G.; Stober, F. M.; Tholen, H.; Troendle, D.; Usai, E.; Vanelderen, L.; Vanhoefer, A.; Vormwald, B.; Barth, C.; Baus, C.; Berger, J.; Böser, C.; Butz, E.; Chwalek, T.; Colombo, F.; De Boer, W.; Descroix, A.; Dierlamm, A.; Fink, S.; Frensch, F.; Friese, R.; Giffels, M.; Gilbert, A.; Haitz, D.; Hartmann, F.; Heindl, S. M.; Husemann, U.; Katkov, I.; Kornmayer, A.; Lobelle Pardo, P.; Maier, B.; Mildner, H.; Mozer, M. U.; Müller, T.; Müller, Th.; Plagge, M.; Quast, G.; Rabbertz, K.; Röcker, S.; Roscher, F.; Schröder, M.; Sieber, G.; Simonis, H. J.; Ulrich, R.; Wagner-Kuhr, J.; Wayand, S.; Weber, M.; Weiler, T.; Williamson, S.; Wöhrmann, C.; Wolf, R.; Anagnostou, G.; Daskalakis, G.; Geralis, T.; Giakoumopoulou, V. A.; Kyriakis, A.; Loukas, D.; Psallidas, A.; Topsis-Giotis, I.; Agapitos, A.; Kesisoglou, S.; Panagiotou, A.; Saoulidou, N.; Tziaferi, E.; Evangelou, I.; Flouris, G.; Foudas, C.; Kokkas, P.; Loukas, N.; Manthos, N.; Papadopoulos, I.; Paradas, E.; Strologas, J.; Bencze, G.; Hajdu, C.; Hidas, P.; Horvath, D.; Sikler, F.; Veszpremi, V.; Vesztergombi, G.; Zsigmond, A. J.; Beni, N.; Czellar, S.; Karancsi, J.; Molnar, J.; Szillasi, Z.; Bartók, M.; Makovec, A.; Raics, P.; Trocsanyi, Z. L.; Ujvari, B.; Choudhury, S.; Mal, P.; Mandal, K.; Sahoo, D. K.; Sahoo, N.; Swain, S. K.; Bansal, S.; Beri, S. B.; Bhatnagar, V.; Chawla, R.; Gupta, R.; Bhawandeep, U.; Kalsi, A. K.; Kaur, A.; Kaur, M.; Kumar, R.; Mehta, A.; Mittal, M.; Singh, J. B.; Walia, G.; Kumar, Ashok; Bhardwaj, A.; Choudhary, B. C.; Garg, R. B.; Keshri, S.; Kumar, A.; Malhotra, S.; Naimuddin, M.; Nishu, N.; Ranjan, K.; Sharma, R.; Sharma, V.; Bhattacharya, R.; Bhattacharya, S.; Chatterjee, K.; Dey, S.; Dutta, S.; Ghosh, S.; Majumdar, N.; Modak, A.; Mondal, K.; Mukhopadhyay, S.; Nandan, S.; Purohit, A.; Roy, A.; Roy, D.; Roy Chowdhury, S.; Sarkar, S.; Sharan, M.; Chudasama, R.; Dutta, D.; Jha, V.; Kumar, V.; Mohanty, A. K.; Pant, L. M.; Shukla, P.; Topkar, A.; Aziz, T.; Banerjee, S.; Bhowmik, S.; Chatterjee, R. M.; Dewanjee, R. K.; Dugad, S.; Ganguly, S.; Ghosh, S.; Guchait, M.; Gurtu, A.; Jain, Sa.; Kole, G.; Kumar, S.; Mahakud, B.; Maity, M.; Majumder, G.; Mazumdar, K.; Mitra, S.; Mohanty, G. B.; Parida, B.; Sarkar, T.; Sur, N.; Sutar, B.; Wickramage, N.; Chauhan, S.; Dube, S.; Kapoor, A.; Kothekar, K.; Rane, A.; Sharma, S.; Bakhshiansohi, H.; Behnamian, H.; Etesami, S. M.; Fahim, A.; Khakzad, M.; Mohammadi Najafabadi, M.; Naseri, M.; Paktinat Mehdiabadi, S.; Rezaei Hosseinabadi, F.; Safarzadeh, B.; Zeinali, M.; Felcini, M.; Grunewald, M.; Abbrescia, M.; Calabria, C.; Caputo, C.; Colaleo, A.; Creanza, D.; Cristella, L.; De Filippis, N.; De Palma, M.; Fiore, L.; Iaselli, G.; Maggi, G.; Maggi, M.; Miniello, G.; My, S.; Nuzzo, S.; Pompili, A.; Pugliese, G.; Radogna, R.; Ranieri, A.; Selvaggi, G.; Silvestris, L.; Venditti, R.; Abbiendi, G.; Battilana, C.; Bonacorsi, D.; Braibant-Giacomelli, S.; Brigliadori, L.; Campanini, R.; Capiluppi, P.; Castro, A.; Cavallo, F. R.; Chhibra, S. S.; Codispoti, G.; Cuffiani, M.; Dallavalle, G. M.; Fabbri, F.; Fanfani, A.; Fasanella, D.; Giacomelli, P.; Grandi, C.; Guiducci, L.; Marcellini, S.; Masetti, G.; Montanari, A.; Navarria, F. L.; Perrotta, A.; Rossi, A. M.; Rovelli, T.; Siroli, G. P.; Tosi, N.; Cappello, G.; Chiorboli, M.; Costa, S.; Di Mattia, A.; Giordano, F.; Potenza, R.; Tricomi, A.; Tuve, C.; Barbagli, G.; Ciulli, V.; Civinini, C.; D'Alessandro, R.; Focardi, E.; Gori, V.; Lenzi, P.; Meschini, M.; Paoletti, S.; Sguazzoni, G.; Viliani, L.; Benussi, L.; Bianco, S.; Fabbri, F.; Piccolo, D.; Primavera, F.; Calvelli, V.; Ferro, F.; Lo Vetere, M.; Monge, M. R.; Robutti, E.; Tosi, S.; Brianza, L.; Dinardo, M. E.; Fiorendi, S.; Gennai, S.; Gerosa, R.; Ghezzi, A.; Govoni, P.; Malvezzi, S.; Manzoni, R. A.; Marzocchi, B.; Menasce, D.; Moroni, L.; Paganoni, M.; Pedrini, D.; Pigazzini, S.; Ragazzi, S.; Redaelli, N.; Tabarelli de Fatis, T.; Buontempo, S.; Cavallo, N.; Di Guida, S.; Esposito, M.; Fabozzi, F.; Iorio, A. O. M.; Lanza, G.; Lista, L.; Meola, S.; Merola, M.; Paolucci, P.; Sciacca, C.; Thyssen, F.; Azzi, P.; Bacchetta, N.; Bellato, M.; Benato, L.; Boletti, A.; Dall'Osso, M.; Dorigo, T.; Fanzago, F.; Gasparini, F.; Gozzelino, A.; Gulmini, M.; Lacaprara, S.; Margoni, M.; Meneguzzo, A. T.; Michelotto, M.; Passaseo, M.; Pazzini, J.; Pegoraro, M.; Pozzobon, N.; Ronchese, P.; Sgaravatto, M.; Simonetto, F.; Torassa, E.; Tosi, M.; Vanini, S.; Ventura, S.; Zanetti, M.; Zotto, P.; Zucchetta, A.; Braghieri, A.; Magnani, A.; Montagna, P.; Ratti, S. P.; Re, V.; Riccardi, C.; Salvini, P.; Vai, I.; Vitulo, P.; Alunni Solestizi, L.; Bilei, G. M.; Ciangottini, D.; Fanò, L.; Lariccia, P.; Leonardi, R.; Mantovani, G.; Menichelli, M.; Saha, A.; Santocchia, A.; Androsov, K.; Azzurri, P.; Bagliesi, G.; Bernardini, J.; Boccali, T.; Castaldi, R.; Ciocci, M. A.; Dell'Orso, R.; Donato, S.; Fedi, G.; Foà, L.; Giassi, A.; Grippo, M. T.; Ligabue, F.; Lomtadze, T.; Martini, L.; Messineo, A.; Palla, F.; Rizzi, A.; Savoy-Navarro, A.; Spagnolo, P.; Tenchini, R.; Tonelli, G.; Venturi, A.; Verdini, P. G.; Barone, L.; Cavallari, F.; D'imperio, G.; Del Re, D.; Diemoz, M.; Gelli, S.; Jorda, C.; Longo, E.; Margaroli, F.; Meridiani, P.; Organtini, G.; Paramatti, R.; Preiato, F.; Rahatlou, S.; Rovelli, C.; Santanastasio, F.; Amapane, N.; Arcidiacono, R.; Argiro, S.; Arneodo, M.; Bellan, R.; Biino, C.; Cartiglia, N.; Costa, M.; Covarelli, R.; Degano, A.; Demaria, N.; Finco, L.; Kiani, B.; Mariotti, C.; Maselli, S.; Migliore, E.; Monaco, V.; Monteil, E.; Obertino, M. M.; Pacher, L.; Pastrone, N.; Pelliccioni, M.; Pinna Angioni, G. L.; Ravera, F.; Romero, A.; Ruspa, M.; Sacchi, R.; Solano, A.; Staiano, A.; Belforte, S.; Candelise, V.; Casarsa, M.; Cossutti, F.; Della Ricca, G.; Gobbo, B.; La Licata, C.; Schizzi, A.; Zanetti, A.; Nam, S. K.; Kim, D. H.; Kim, G. N.; Kim, M. S.; Kong, D. J.; Lee, S.; Lee, S. W.; Oh, Y. D.; Sakharov, A.; Son, D. C.; Brochero Cifuentes, J. A.; Kim, H.; Kim, T. J.; Song, S.; Cho, S.; Choi, S.; Go, Y.; Gyun, D.; Hong, B.; Kim, H.; Kim, Y.; Lee, B.; Lee, K.; Lee, K. S.; Lee, S.; Lim, J.; Park, S. K.; Roh, Y.; Yoo, H. D.; Choi, M.; Kim, H.; Kim, J. H.; Lee, J. S. H.; Park, I. C.; Ryu, G.; Ryu, M. S.; Choi, Y.; Goh, J.; Kim, D.; Kwon, E.; Lee, J.; Yu, I.; Dudenas, V.; Juodagalvis, A.; Vaitkus, J.; Ahmed, I.; Ibrahim, Z. A.; Komaragiri, J. R.; Md Ali, M. A. B.; Mohamad Idris, F.; Wan Abdullah, W. A. T.; Yusli, M. N.; Zolkapli, Z.; Casimiro Linares, E.; Castilla-Valdez, H.; De La Cruz-Burelo, E.; Heredia-De La Cruz, I.; Hernandez-Almada, A.; Lopez-Fernandez, R.; Mejia Guisao, J.; Sanchez-Hernandez, A.; Carrillo Moreno, S.; Vazquez Valencia, F.; Pedraza, I.; Salazar Ibarguen, H. A.; Morelos Pineda, A.; Krofcheck, D.; Butler, P. H.; Ahmad, A.; Ahmad, M.; Hassan, Q.; Hoorani, H. R.; Khan, W. A.; Khurshid, T.; Shoaib, M.; Waqas, M.; Bialkowska, H.; Bluj, M.; Boimska, B.; Frueboes, T.; Górski, M.; Kazana, M.; Nawrocki, K.; Romanowska-Rybinska, K.; Szleper, M.; Traczyk, P.; Zalewski, P.; Brona, G.; Bunkowski, K.; Byszuk, A.; Doroba, K.; Kalinowski, A.; Konecki, M.; Krolikowski, J.; Misiura, M.; Olszewski, M.; Walczak, M.; Bargassa, P.; Beirão Da Cruz E Silva, C.; Di Francesco, A.; Faccioli, P.; Ferreira Parracho, P. G.; Gallinaro, M.; Hollar, J.; Leonardo, N.; Lloret Iglesias, L.; Nemallapudi, M. V.; Nguyen, F.; Rodrigues Antunes, J.; Seixas, J.; Toldaiev, O.; Vadruccio, D.; Varela, J.; Vischia, P.; Afanasiev, S.; Bunin, P.; Gavrilenko, M.; Golutvin, I.; Gorbunov, I.; Kamenev, A.; Karjavin, V.; Lanev, A.; Malakhov, A.; Matveev, V.; Moisenz, P.; Palichik, V.; Perelygin, V.; Shmatov, S.; Shulha, S.; Skatchkov, N.; Smirnov, V.; Voytishin, N.; Zarubin, A.; Golovtsov, V.; Ivanov, Y.; Kim, V.; Kuznetsova, E.; Levchenko, P.; Murzin, V.; Oreshkin, V.; Smirnov, I.; Sulimov, V.; Uvarov, L.; Vavilov, S.; Vorobyev, A.; Andreev, Yu.; Dermenev, A.; Gninenko, S.; Golubev, N.; Karneyeu, A.; Kirsanov, M.; Krasnikov, N.; Pashenkov, A.; Tlisov, D.; Toropin, A.; Epshteyn, V.; Gavrilov, V.; Lychkovskaya, N.; Popov, V.; Pozdnyakov, I.; Safronov, G.; Spiridonov, A.; Vlasov, E.; Zhokin, A.; Chadeeva, M.; Chistov, R.; Danilov, M.; Rusinov, V.; Tarkovskii, E.; Andreev, V.; Azarkin, M.; Dremin, I.; Kirakosyan, M.; Leonidov, A.; Mesyats, G.; Rusakov, S. V.; Baskakov, A.; Belyaev, A.; Boos, E.; Demiyanov, A.; Ershov, A.; Gribushin, A.; Kodolova, O.; Korotkikh, V.; Lokhtin, I.; Miagkov, I.; Obraztsov, S.; Petrushanko, S.; Savrin, V.; Snigirev, A.; Vardanyan, I.; Azhgirey, I.; Bayshev, I.; Bitioukov, S.; Kachanov, V.; Kalinin, A.; Konstantinov, D.; Krychkine, V.; Petrov, V.; Ryutin, R.; Sobol, A.; Tourtchanovitch, L.; Troshin, S.; Tyurin, N.; Uzunian, A.; Volkov, A.; Adzic, P.; Cirkovic, P.; Devetak, D.; Milosevic, J.; Rekovic, V.; Alcaraz Maestre, J.; Calvo, E.; Cerrada, M.; Chamizo Llatas, M.; Colino, N.; De La Cruz, B.; Delgado Peris, A.; Escalante Del Valle, A.; Fernandez Bedoya, C.; Fernández Ramos, J. P.; Flix, J.; Fouz, M. C.; Garcia-Abia, P.; Gonzalez Lopez, O.; Goy Lopez, S.; Hernandez, J. M.; Josa, M. I.; Navarro De Martino, E.; Pérez-Calero Yzquierdo, A.; Puerta Pelayo, J.; Quintario Olmeda, A.; Redondo, I.; Romero, L.; Soares, M. S.; de Trocóniz, J. F.; Missiroli, M.; Moran, D.; Cuevas, J.; Fernandez Menendez, J.; Folgueras, S.; Gonzalez Caballero, I.; Palencia Cortezon, E.; Vizan Garcia, J. M.; Cabrillo, I. J.; Calderon, A.; Castiñeiras De Saa, J. R.; Curras, E.; De Castro Manzano, P.; Fernandez, M.; Garcia-Ferrero, J.; Gomez, G.; Lopez Virto, A.; Marco, J.; Marco, R.; Martinez Rivero, C.; Matorras, F.; Piedra Gomez, J.; Rodrigo, T.; Rodríguez-Marrero, A. Y.; Ruiz-Jimeno, A.; Scodellaro, L.; Trevisani, N.; Vila, I.; Vilar Cortabitarte, R.; Abbaneo, D.; Auffray, E.; Auzinger, G.; Bachtis, M.; Baillon, P.; Ball, A. H.; Barney, D.; Benaglia, A.; Benhabib, L.; Berruti, G. M.; Bloch, P.; Bocci, A.; Bonato, A.; Botta, C.; Breuker, H.; Camporesi, T.; Castello, R.; Cepeda, M.; Cerminara, G.; D'Alfonso, M.; d'Enterria, D.; Dabrowski, A.; Daponte, V.; David, A.; De Gruttola, M.; De Guio, F.; De Roeck, A.; Di Marco, E.; Dobson, M.; Dordevic, M.; Dorney, B.; du Pree, T.; Duggan, D.; Dünser, M.; Dupont, N.; Elliott-Peisert, A.; Franzoni, G.; Fulcher, J.; Funk, W.; Gigi, D.; Gill, K.; Girone, M.; Glege, F.; Guida, R.; Gundacker, S.; Guthoff, M.; Hammer, J.; Harris, P.; Hegeman, J.; Innocente, V.; Janot, P.; Kirschenmann, H.; Knünz, V.; Kortelainen, M. J.; Kousouris, K.; Lecoq, P.; Lourenço, C.; Lucchini, M. T.; Magini, N.; Malgeri, L.; Mannelli, M.; Martelli, A.; Masetti, L.; Meijers, F.; Mersi, S.; Meschi, E.; Moortgat, F.; Morovic, S.; Mulders, M.; Neugebauer, H.; Orfanelli, S.; Orsini, L.; Pape, L.; Perez, E.; Peruzzi, M.; Petrilli, A.; Petrucciani, G.; Pfeiffer, A.; Pierini, M.; Piparo, D.; Racz, A.; Reis, T.; Rolandi, G.; Rovere, M.; Ruan, M.; Sakulin, H.; Sauvan, J. B.; Schäfer, C.; Schwick, C.; Seidel, M.; Sharma, A.; Silva, P.; Simon, M.; Sphicas, P.; Steggemann, J.; Stoye, M.; Takahashi, Y.; Treille, D.; Triossi, A.; Tsirou, A.; Veckalns, V.; Veres, G. I.; Wardle, N.; Wöhri, H. K.; Zagozdzinska, A.; Zeuner, W. D.; Bertl, W.; Deiters, K.; Erdmann, W.; Horisberger, R.; Ingram, Q.; Kaestli, H. C.; Kotlinski, D.; Langenegger, U.; Rohe, T.; Bachmair, F.; Bäni, L.; Bianchini, L.; Casal, B.; Dissertori, G.; Dittmar, M.; Donegà, M.; Eller, P.; Grab, C.; Heidegger, C.; Hits, D.; Hoss, J.; Kasieczka, G.; Lecomte, P.; Lustermann, W.; Mangano, B.; Marionneau, M.; Martinez Ruiz del Arbol, P.; Masciovecchio, M.; Meinhard, M. T.; Meister, D.; Micheli, F.; Musella, P.; Nessi-Tedaldi, F.; Pandolfi, F.; Pata, J.; Pauss, F.; Perrin, G.; Perrozzi, L.; Quittnat, M.; Rossini, M.; Schönenberger, M.; Starodumov, A.; Takahashi, M.; Tavolaro, V. R.; Theofilatos, K.; Wallny, R.; Aarrestad, T. K.; Amsler, C.; Caminada, L.; Canelli, M. F.; Chiochia, V.; De Cosa, A.; Galloni, C.; Hinzmann, A.; Hreus, T.; Kilminster, B.; Lange, C.; Ngadiuba, J.; Pinna, D.; Rauco, G.; Robmann, P.; Salerno, D.; Yang, Y.; Chen, K. H.; Doan, T. H.; Jain, Sh.; Khurana, R.; Konyushikhin, M.; Kuo, C. M.; Lin, W.; Lu, Y. J.; Pozdnyakov, A.; Yu, S. S.; Kumar, Arun; Chang, P.; Chang, Y. H.; Chang, Y. W.; Chao, Y.; Chen, K. F.; Chen, P. H.; Dietz, C.; Fiori, F.; Grundler, U.; Hou, W.-S.; Hsiung, Y.; Liu, Y. F.; Lu, R.-S.; Miñano Moya, M.; Petrakou, E.; Tsai, J. f.; Tzeng, Y. M.; Asavapibhop, B.; Kovitanggoon, K.; Singh, G.; Srimanobhas, N.; Suwonjandee, N.; Adiguzel, A.; Bakirci, M. N.; Cerci, S.; Damarseckin, S.; Demiroglu, Z. S.; Dozen, C.; Eskut, E.; Girgis, S.; Gokbulut, G.; Guler, Y.; Gurpinar, E.; Hos, I.; Kangal, E. E.; Onengut, G.; Ozdemir, K.; Ozturk, S.; Polatoz, A.; Sunar Cerci, D.; Zorbilmez, C.; Bilin, B.; Bilmis, S.; Isildak, B.; Karapinar, G.; Yalvac, M.; Zeyrek, M.; Gülmez, E.; Kaya, M.; Kaya, O.; Yetkin, E. A.; Yetkin, T.; Cakir, A.; Cankocak, K.; Sen, S.; Grynyov, B.; Levchuk, L.; Sorokin, P.; Aggleton, R.; Ball, F.; Beck, L.; Brooke, J. J.; Burns, D.; Clement, E.; Cussans, D.; Flacher, H.; Goldstein, J.; Grimes, M.; Heath, G. P.; Heath, H. F.; Jacob, J.; Kreczko, L.; Lucas, C.; Meng, Z.; Newbold, D. M.; Paramesvaran, S.; Poll, A.; Sakuma, T.; Seif El Nasr-storey, S.; Senkin, S.; Smith, D.; Smith, V. J.; Belyaev, A.; Brew, C.; Brown, R. M.; Calligaris, L.; Cieri, D.; Cockerill, D. J. A.; Coughlan, J. A.; Harder, K.; Harper, S.; Olaiya, E.; Petyt, D.; Shepherd-Themistocleous, C. H.; Thea, A.; Tomalin, I. R.; Williams, T.; Worm, S. D.; Baber, M.; Bainbridge, R.; Buchmuller, O.; Bundock, A.; Burton, D.; Casasso, S.; Citron, M.; Colling, D.; Corpe, L.; Dauncey, P.; Davies, G.; De Wit, A.; Della Negra, M.; Dunne, P.; Elwood, A.; Futyan, D.; Hall, G.; Iles, G.; Lane, R.; Lucas, R.; Lyons, L.; Magnan, A.-M.; Malik, S.; Mastrolorenzo, L.; Nash, J.; Nikitenko, A.; Pela, J.; Penning, B.; Pesaresi, M.; Raymond, D. M.; Richards, A.; Rose, A.; Seez, C.; Tapper, A.; Uchida, K.; Vazquez Acosta, M.; Virdee, T.; Zenz, S. C.; Cole, J. E.; Hobson, P. R.; Khan, A.; Kyberd, P.; Leslie, D.; Reid, I. D.; Symonds, P.; Teodorescu, L.; Turner, M.; Borzou, A.; Call, K.; Dittmann, J.; Hatakeyama, K.; Liu, H.; Pastika, N.; Charaf, O.; Cooper, S. I.; Henderson, C.; Rumerio, P.; Arcaro, D.; Avetisyan, A.; Bose, T.; Gastler, D.; Rankin, D.; Richardson, C.; Rohlf, J.; Sulak, L.; Zou, D.; Alimena, J.; Benelli, G.; Berry, E.; Cutts, D.; Ferapontov, A.; Garabedian, A.; Hakala, J.; Heintz, U.; Jesus, O.; Laird, E.; Landsberg, G.; Mao, Z.; Narain, M.; Piperov, S.; Sagir, S.; Syarif, R.; Breedon, R.; Breto, G.; Calderon De La Barca Sanchez, M.; Chauhan, S.; Chertok, M.; Conway, J.; Conway, R.; Cox, P. T.; Erbacher, R.; Funk, G.; Gardner, M.; Ko, W.; Lander, R.; Mclean, C.; Mulhearn, M.; Pellett, D.; Pilot, J.; Ricci-Tam, F.; Shalhout, S.; Smith, J.; Squires, M.; Stolp, D.; Tripathi, M.; Wilbur, S.; Yohay, R.; Cousins, R.; Everaerts, P.; Florent, A.; Hauser, J.; Ignatenko, M.; Saltzberg, D.; Takasugi, E.; Valuev, V.; Weber, M.; Burt, K.; Clare, R.; Ellison, J.; Gary, J. W.; Hanson, G.; Heilman, J.; Paneva, M. Ivova; Jandir, P.; Kennedy, E.; Lacroix, F.; Long, O. R.; Malberti, M.; Olmedo Negrete, M.; Shrinivas, A.; Wei, H.; Wimpenny, S.; Yates, B. R.; Branson, J. G.; Cerati, G. B.; Cittolin, S.; D'Agnolo, R. T.; Derdzinski, M.; Holzner, A.; Kelley, R.; Klein, D.; Letts, J.; Macneill, I.; Olivito, D.; Padhi, S.; Pieri, M.; Sani, M.; Sharma, V.; Simon, S.; Tadel, M.; Vartak, A.; Wasserbaech, S.; Welke, C.; Würthwein, F.; Yagil, A.; Zevi Della Porta, G.; Bradmiller-Feld, J.; Campagnari, C.; Dishaw, A.; Dutta, V.; Flowers, K.; Franco Sevilla, M.; Geffert, P.; George, C.; Golf, F.; Gouskos, L.; Gran, J.; Incandela, J.; Mccoll, N.; Mullin, S. D.; Richman, J.; Stuart, D.; Suarez, I.; West, C.; Yoo, J.; Anderson, D.; Apresyan, A.; Bendavid, J.; Bornheim, A.; Bunn, J.; Chen, Y.; Duarte, J.; Mott, A.; Newman, H. B.; Pena, C.; Spiropulu, M.; Vlimant, J. R.; Xie, S.; Zhu, R. Y.; Andrews, M. B.; Azzolini, V.; Calamba, A.; Carlson, B.; Ferguson, T.; Paulini, M.; Russ, J.; Sun, M.; Vogel, H.; Vorobiev, I.; Cumalat, J. P.; Ford, W. T.; Gaz, A.; Jensen, F.; Johnson, A.; Krohn, M.; Mulholland, T.; Nauenberg, U.; Stenson, K.; Wagner, S. R.; Alexander, J.; Chatterjee, A.; Chaves, J.; Chu, J.; Dittmer, S.; Eggert, N.; Mirman, N.; Nicolas Kaufman, G.; Patterson, J. R.; Rinkevicius, A.; Ryd, A.; Skinnari, L.; Soffi, L.; Sun, W.; Tan, S. M.; Teo, W. D.; Thom, J.; Thompson, J.; Tucker, J.; Weng, Y.; Wittich, P.; Abdullin, S.; Albrow, M.; Apollinari, G.; Banerjee, S.; Bauerdick, L. A. T.; Beretvas, A.; Berryhill, J.; Bhat, P. C.; Bolla, G.; Burkett, K.; Butler, J. N.; Cheung, H. W. K.; Chlebana, F.; Cihangir, S.; Elvira, V. D.; Fisk, I.; Freeman, J.; Gottschalk, E.; Gray, L.; Green, D.; Grünendahl, S.; Gutsche, O.; Hanlon, J.; Hare, D.; Harris, R. M.; Hasegawa, S.; Hirschauer, J.; Hu, Z.; Jayatilaka, B.; Jindariani, S.; Johnson, M.; Joshi, U.; Klima, B.; Kreis, B.; Lammel, S.; Lewis, J.; Linacre, J.; Lincoln, D.; Lipton, R.; Liu, T.; Lopes De Sá, R.; Lykken, J.; Maeshima, K.; Marraffino, J. M.; Maruyama, S.; Mason, D.; McBride, P.; Merkel, P.; Mrenna, S.; Nahn, S.; Newman-Holmes, C.; O'Dell, V.; Pedro, K.; Prokofyev, O.; Rakness, G.; Sexton-Kennedy, E.; Soha, A.; Spalding, W. J.; Spiegel, L.; Stoynev, S.; Strobbe, N.; Taylor, L.; Tkaczyk, S.; Tran, N. V.; Uplegger, L.; Vaandering, E. W.; Vernieri, C.; Verzocchi, M.; Vidal, R.; Wang, M.; Weber, H. A.; Whitbeck, A.; Acosta, D.; Avery, P.; Bortignon, P.; Bourilkov, D.; Brinkerhoff, A.; Carnes, A.; Carver, M.; Curry, D.; Das, S.; Field, R. D.; Furic, I. K.; Konigsberg, J.; Korytov, A.; Kotov, K.; Ma, P.; Matchev, K.; Mei, H.; Milenovic, P.; Mitselmakher, G.; Rank, D.; Rossin, R.; Shchutska, L.; Snowball, M.; Sperka, D.; Terentyev, N.; Thomas, L.; Wang, J.; Wang, S.; Yelton, J.; Linn, S.; Markowitz, P.; Martinez, G.; Rodriguez, J. L.; Ackert, A.; Adams, J. R.; Adams, T.; Askew, A.; Bein, S.; Bochenek, J.; Diamond, B.; Haas, J.; Hagopian, S.; Hagopian, V.; Johnson, K. F.; Khatiwada, A.; Prosper, H.; Weinberg, M.; Baarmand, M. M.; Bhopatkar, V.; Colafranceschi, S.; Hohlmann, M.; Kalakhety, H.; Noonan, D.; Roy, T.; Yumiceva, F.; Adams, M. R.; Apanasevich, L.; Berry, D.; Betts, R. R.; Bucinskaite, I.; Cavanaugh, R.; Evdokimov, O.; Gauthier, L.; Gerber, C. E.; Hofman, D. J.; Kurt, P.; O'Brien, C.; Sandoval Gonzalez, I. D.; Turner, P.; Varelas, N.; Wu, Z.; Zakaria, M.; Zhang, J.; Bilki, B.; Clarida, W.; Dilsiz, K.; Durgut, S.; Gandrajula, R. P.; Haytmyradov, M.; Khristenko, V.; Merlo, J.-P.; Mermerkaya, H.; Mestvirishvili, A.; Moeller, A.; Nachtman, J.; Ogul, H.; Onel, Y.; Ozok, F.; Penzo, A.; Snyder, C.; Tiras, E.; Wetzel, J.; Yi, K.; Anderson, I.; Barnett, B. A.; Blumenfeld, B.; Cocoros, A.; Eminizer, N.; Fehling, D.; Feng, L.; Gritsan, A. V.; Maksimovic, P.; Osherson, M.; Roskes, J.; Sarica, U.; Swartz, M.; Xiao, M.; Xin, Y.; You, C.; Baringer, P.; Bean, A.; Bruner, C.; Castle, J.; Kenny, R. P., III; Kropivnitskaya, A.; Majumder, D.; Malek, M.; Mcbrayer, W.; Murray, M.; Sanders, S.; Stringer, R.; Tapia Takaki, J. D.; Wang, Q.; Ivanov, A.; Kaadze, K.; Khalil, S.; Makouski, M.; Maravin, Y.; Mohammadi, A.; Saini, L. K.; Skhirtladze, N.; Toda, S.; Lange, D.; Rebassoo, F.; Wright, D.; Anelli, C.; Baden, A.; Baron, O.; Belloni, A.; Calvert, B.; Eno, S. C.; Ferraioli, C.; Gomez, J. A.; Hadley, N. J.; Jabeen, S.; Kellogg, R. G.; Kolberg, T.; Kunkle, J.; Lu, Y.; Mignerey, A. C.; Shin, Y. H.; Skuja, A.; Tonjes, M. B.; Tonwar, S. C.; Apyan, A.; Barbieri, R.; Baty, A.; Bi, R.; Bierwagen, K.; Brandt, S.; Busza, W.; Cali, I. A.; Demiragli, Z.; Di Matteo, L.; Gomez Ceballos, G.; Goncharov, M.; Gulhan, D.; Iiyama, Y.; Innocenti, G. M.; Klute, M.; Kovalskyi, D.; Krajczar, K.; Lai, Y. S.; Lee, Y.-J.; Levin, A.; Luckey, P. D.; Marini, A. C.; Mcginn, C.; Mironov, C.; Narayanan, S.; Niu, X.; Paus, C.; Roland, C.; Roland, G.; Salfeld-Nebgen, J.; Stephans, G. S. F.; Sumorok, K.; Tatar, K.; Varma, M.; Velicanu, D.; Veverka, J.; Wang, J.; Wang, T. W.; Wyslouch, B.; Yang, M.; Zhukova, V.; Benvenuti, A. C.; Dahmes, B.; Evans, A.; Finkel, A.; Gude, A.; Hansen, P.; Kalafut, S.; Kao, S. C.; Klapoetke, K.; Kubota, Y.; Lesko, Z.; Mans, J.; Nourbakhsh, S.; Ruckstuhl, N.; Rusack, R.; Tambe, N.; Turkewitz, J.; Acosta, J. G.; Oliveros, S.; Avdeeva, E.; Bartek, R.; Bloom, K.; Bose, S.; Claes, D. R.; Dominguez, A.; Fangmeier, C.; Gonzalez Suarez, R.; Kamalieddin, R.; Knowlton, D.; Kravchenko, I.; Meier, F.; Monroy, J.; Ratnikov, F.; Siado, J. E.; Snow, G. R.; Stieger, B.; Alyari, M.; Dolen, J.; George, J.; Godshalk, A.; Harrington, C.; Iashvili, I.; Kaisen, J.; Kharchilava, A.; Kumar, A.; Parker, A.; Rappoccio, S.; Roozbahani, B.; Alverson, G.; Barberis, E.; Baumgartel, D.; Chasco, M.; Hortiangtham, A.; Massironi, A.; Morse, D. M.; Nash, D.; Orimoto, T.; Teixeira De Lima, R.; Trocino, D.; Wang, R.-J.; Wood, D.; Zhang, J.; Bhattacharya, S.; Hahn, K. A.; Kubik, A.; Low, J. F.; Mucia, N.; Odell, N.; Pollack, B.; Schmitt, M. H.; Sung, K.; Trovato, M.; Velasco, M.; Dev, N.; Hildreth, M.; Jessop, C.; Karmgard, D. J.; Kellams, N.; Lannon, K.; Marinelli, N.; Meng, F.; Mueller, C.; Musienko, Y.; Planer, M.; Reinsvold, A.; Ruchti, R.; Rupprecht, N.; Smith, G.; Taroni, S.; Valls, N.; Wayne, M.; Wolf, M.; Woodard, A.; Antonelli, L.; Brinson, J.; Bylsma, B.; Durkin, L. S.; Flowers, S.; Hart, A.; Hill, C.; Hughes, R.; Ji, W.; Ling, T. Y.; Liu, B.; Luo, W.; Puigh, D.; Rodenburg, M.; Winer, B. L.; Wulsin, H. W.; Driga, O.; Elmer, P.; Hardenbrook, J.; Hebda, P.; Koay, S. A.; Lujan, P.; Marlow, D.; Medvedeva, T.; Mooney, M.; Olsen, J.; Palmer, C.; Piroué, P.; Stickland, D.; Tully, C.; Zuranski, A.; Malik, S.; Barker, A.; Barnes, V. E.; Benedetti, D.; Bortoletto, D.; Gutay, L.; Jha, M. K.; Jones, M.; Jung, A. W.; Jung, K.; Miller, D. H.; Neumeister, N.; Radburn-Smith, B. C.; Shi, X.; Shipsey, I.; Silvers, D.; Sun, J.; Svyatkovskiy, A.; Wang, F.; Xie, W.; Xu, L.; Parashar, N.; Stupak, J.; Adair, A.; Akgun, B.; Chen, Z.; Ecklund, K. M.; Geurts, F. J. M.; Guilbaud, M.; Li, W.; Michlin, B.; Northup, M.; Padley, B. P.; Redjimi, R.; Roberts, J.; Rorie, J.; Tu, Z.; Zabel, J.; Betchart, B.; Bodek, A.; de Barbaro, P.; Demina, R.; Eshaq, Y.; Ferbel, T.; Galanti, M.; Garcia-Bellido, A.; Han, J.; Hindrichs, O.; Khukhunaishvili, A.; Lo, K. H.; Tan, P.; Verzetti, M.; Chou, J. P.; Contreras-Campana, E.; Ferencek, D.; Gershtein, Y.; Halkiadakis, E.; Heindl, M.; Hidas, D.; Hughes, E.; Kaplan, S.; Kunnawalkam Elayavalli, R.; Lath, A.; Nash, K.; Saka, H.; Salur, S.; Schnetzer, S.; Sheffield, D.; Somalwar, S.; Stone, R.; Thomas, S.; Thomassen, P.; Walker, M.; Foerster, M.; Heideman, J.; Riley, G.; Rose, K.; Spanier, S.; Thapa, K.; Bouhali, O.; Castaneda Hernandez, A.; Celik, A.; Dalchenko, M.; De Mattia, M.; Delgado, A.; Dildick, S.; Eusebi, R.; Gilmore, J.; Huang, T.; Kamon, T.; Krutelyov, V.; Mueller, R.; Osipenkov, I.; Pakhotin, Y.; Patel, R.; Perloff, A.; Rathjens, D.; Rose, A.; Safonov, A.; Tatarinov, A.; Ulmer, K. A.; Akchurin, N.; Cowden, C.; Damgov, J.; Dragoiu, C.; Dudero, P. R.; Faulkner, J.; Kunori, S.; Lamichhane, K.; Lee, S. W.; Libeiro, T.; Undleeb, S.; Volobouev, I.; Wang, Z.; Appelt, E.; Delannoy, A. G.; Greene, S.; Gurrola, A.; Janjam, R.; Johns, W.; Maguire, C.; Mao, Y.; Melo, A.; Ni, H.; Sheldon, P.; Tuo, S.; Velkovska, J.; Xu, Q.; Arenton, M. W.; Barria, P.; Cox, B.; Francis, B.; Goodell, J.; Hirosky, R.; Ledovskoy, A.; Li, H.; Neu, C.; Sinthuprasith, T.; Sun, X.; Wang, Y.; Wolfe, E.; Wood, J.; Xia, F.; Clarke, C.; Harr, R.; Karchin, P. E.; Kottachchi Kankanamge Don, C.; Lamichhane, P.; Sturdy, J.; Belknap, D. A.; Carlsmith, D.; Dasu, S.; Dodd, L.; Duric, S.; Gomber, B.; Grothe, M.; Herndon, M.; Hervé, A.; Klabbers, P.; Lanaro, A.; Levine, A.; Long, K.; Loveless, R.; Mohapatra, A.; Ojalvo, I.; Perry, T.; Pierro, G. A.; Polese, G.; Ruggles, T.; Sarangi, T.; Savin, A.; Sharma, A.; Smith, N.; Smith, W. H.; Taylor, D.; Verwilligen, P.; Woods, N.; CMS Collaboration

2017-09-01

The cross section for coherent J / ψ photoproduction accompanied by at least one neutron on one side of the interaction point and no neutron activity on the other side, Xn0n, is measured with the CMS experiment in ultra-peripheral PbPb collisions at √{sNN} = 2.76TeV. The analysis is based on a data sample corresponding to an integrated luminosity of 159μb-1, collected during the 2011 PbPb run. The J / ψ mesons are reconstructed in the dimuon decay channel, while neutrons are detected using zero degree calorimeters. The measured cross section is dσSUB>Xn0n/SUB>coh/dy (J / ψ) = 0.36 ± 0.04(stat) ± 0.04(syst) mb in the rapidity interval 1.8 < | y | < 2.3. Using a model for the relative rate of coherent photoproduction processes, this Xn0n measurement gives a total coherent photoproduction cross section of dσcoh / dy (J / ψ) = 1.82 ± 0.22(stat) ± 0.20(syst) ± 0.19(theo) mb. The data strongly disfavor the impulse approximation model prediction, indicating that nuclear effects are needed to describe coherent J / ψ photoproduction in γ + Pb interactions. The data are found to be consistent with the leading twist approximation, which includes nuclear gluon shadowing.

Three-Dimensional Navier-Stokes Simulations with Two-Equation Turbulence Models of Intersecting Shock-Waves/Turbulent Boundary Layer at Mach 8.3

NASA Technical Reports Server (NTRS)

Bardina, J. E.; Coakley, T. J.

1994-01-01

An investigation of the numerical simulation with two-equation turbulence models of a three-dimensional hypersonic intersecting (SWTBL) shock-wave/turbulent boundary layer interaction flow is presented. The flows are solved with an efficient implicit upwind flux-difference split Reynolds-averaged Navier-Stokes code. Numerical results are compared with experimental data for a flow at Mach 8.28 and Reynolds number 5.3x10(exp 6) with crossing shock-waves and expansion fans generated by two lateral 15 fins located on top of a cold-wall plate. This experiment belongs to the hypersonic database for modeling validation. Simulations show the development of two primary counter-rotating cross-flow vortices and secondary turbulent structures under the main vortices and in each corner singularity inside the turbulent boundary layer. A significant loss of total pressure is produced by the complex interaction between the main vortices and the uplifted jet stream of the boundary layer. The overall agreement between computational and experimental data is generally good. The turbulence modeling corrections show improvements in the predictions of surface heat transfer distribution and an increase in the strength of the cross-flow vortices. Accurate predictions of the outflow flowfield is found to require accurate modeling of the laminar/turbulent boundary layers on the fin walls.

A coincidence measurement of the D(gamma, pp pi(-)) cross section in the region of the Delta resonance

NASA Astrophysics Data System (ADS)

Quraan, Maher A.

Photonuclear reactions are excellent means for understanding final state interactions (FSI). The photon interacts only electromagnetically, allowing a clean separation of the strong interaction channels in the final state. The availability of high duty factor electron machines and large acceptance detectors in the past decade have allowed a further investigation of these effects covering wider regions of phase space. In this experiment, we have successfully measured the D(/gamma, pp/pi/sp-) reaction cross section at the Saskatchewan Accelerator Laboratory (SAL) utilizing the Saskatchewan- Alberta Large Acceptance Detector (SALAD). This is the first measurement of the /gamma D /to pp/pi/sp--cross section covering a wide range of phase space with an attempt to study the FSI's and the /Delta - N interaction that has successfully reproduced the normalizations. The cross section for this reaction is compared to the calculation of J. M. Laget. Laget's theory is quite successful in describing the shapes of the distributions. as well as the overall magnitude of the cross section. The different FSI's and the /Delta - N interaction have an overall effect of 10%-15% on the single differential cross section, with the calculation that includes /Delta - N interaction having the best normalization compared to the data.

Mapping the epitopes of a neutralizing antibody fragment directed against the lethal factor of Bacillus anthracis and cross-reacting with the homologous edema factor.

PubMed

Thullier, Philippe; Avril, Arnaud; Mathieu, Jacques; Behrens, Christian K; Pellequer, Jean-Luc; Pelat, Thibaut

2013-01-01

The lethal toxin (LT) of Bacillus anthracis, composed of the protective antigen (PA) and the lethal factor (LF), plays an essential role in anthrax pathogenesis. PA also interacts with the edema factor (EF, 20% identity with LF) to form the edema toxin (ET), which has a lesser role in anthrax pathogenesis. The first recombinant antibody fragment directed against LF was scFv 2LF; it neutralizes LT by blocking the interaction between PA and LF. Here, we report that scFv 2LF cross-reacts with EF and cross-neutralizes ET, and we present an in silico method taking advantage of this cross-reactivity to map the epitope of scFv 2LF on both LF and EF. This method identified five epitope candidates on LF, constituted of a total of 32 residues, which were tested experimentally by mutating the residues to alanine. This combined approach precisely identified the epitope of scFv 2LF on LF as five residues (H229, R230, Q234, L235 and Y236), of which three were missed by the consensus epitope candidate identified by pre-existing in silico methods. The homolog of this epitope on EF (H253, R254, E258, L259 and Y260) was experimentally confirmed to constitute the epitope of scFv 2LF on EF. Other inhibitors, including synthetic molecules, could be used to target these epitopes for therapeutic purposes. The in silico method presented here may be of more general interest.

Layered semiconductor neutron detectors

DOEpatents

Mao, Samuel S; Perry, Dale L

2013-12-10

Room temperature operating solid state hand held neutron detectors integrate one or more relatively thin layers of a high neutron interaction cross-section element or materials with semiconductor detectors. The high neutron interaction cross-section element (e.g., Gd, B or Li) or materials comprising at least one high neutron interaction cross-section element can be in the form of unstructured layers or micro- or nano-structured arrays. Such architecture provides high efficiency neutron detector devices by capturing substantially more carriers produced from high energy .alpha.-particles or .gamma.-photons generated by neutron interaction.

A critical evaluation of various methods for the analysis of flow-solid interaction in a nest of thin cylinders subjected to cross flows

NASA Technical Reports Server (NTRS)

Kim, Sang-Wook

1987-01-01

Various experimental, analytical, and numerical analysis methods for flow-solid interaction of a nest of cylinders subjected to cross flows are reviewed. A nest of cylinders subjected to cross flows can be found in numerous engineering applications including the Space Shuttle Maine Engine-Main Injector Assembly (SSME-MIA) and nuclear reactor heat exchangers. Despite its extreme importance in engineering applications, understanding of the flow-solid interaction process is quite limited and design of the tube banks are mostly dependent on experiments and/or experimental correlation equations. For future development of major numerical analysis methods for the flow-solid interaction of a nest of cylinders subjected to cross flow, various turbulence models, nonlinear structural dynamics, and existing laminar flow-solid interaction analysis methods are included.

The advancement of chemical cross-linking and mass spectrometry for structural proteomics: from single proteins to protein interaction networks.

PubMed

Sinz, Andrea

2014-12-01

During the last 15 years, chemical cross-linking combined with mass spectrometry (MS) and computational modeling has advanced from investigating 3D-structures of isolated proteins to deciphering protein interaction networks. In this article, the author discusses the advent, the development and the current status of the chemical cross-linking/MS strategy in the context of recent technological developments. A direct way to probe in vivo protein-protein interactions is by site-specific incorporation of genetically encoded photo-reactive amino acids or by non-directed incorporation of photo-reactive amino acids. As the chemical cross-linking/MS approach allows the capture of transient and weak interactions, it has the potential to become a routine technique for unraveling protein interaction networks in their natural cellular environment.

Weighting of topologically different interactions in a model of two-dimensional polymer collapse.

PubMed

Bedini, Andrea; Owczarek, Aleksander L; Prellberg, Thomas

2013-01-01

We study by computer simulation a recently introduced generalized model of self-interacting self-avoiding trails on the square lattice that distinguishes two topologically different types of self-interaction: namely, crossings where the trail passes across itself and collisions where the lattice path visits the same site without crossing. This model generalizes the canonical interacting self-avoiding trail model of polymer collapse, which has a strongly divergent specific heat at its transition point. We confirm the recent prediction that the asymmetry does not affect the universality class for a range of asymmetry. Certainly, where the weighting of collisions outweighs that of crossings this is well supported numerically. When crossings are weighted heavily relative to collisions, the collapse transition reverts to the canonical θ-point-like behavior found in interacting self-avoiding walks.

Probing the cross-effect of strains in non-linear elasticity of nearly regular polymer networks by pure shear deformation.

PubMed

Katashima, Takuya; Urayama, Kenji; Chung, Ung-il; Sakai, Takamasa

2015-05-07

The pure shear deformation of the Tetra-polyethylene glycol gels reveals the presence of an explicit cross-effect of strains in the strain energy density function even for the polymer networks with nearly regular structure including no appreciable amount of structural defect such as trapped entanglement. This result is in contrast to the expectation of the classical Gaussian network model (Neo Hookean model), i.e., the vanishing of the cross effect in regular networks with no trapped entanglement. The results show that (1) the cross effect of strains is not dependent on the network-strand length; (2) the cross effect is not affected by the presence of non-network strands; (3) the cross effect is proportional to the network polymer concentration including both elastically effective and ineffective strands; (4) no cross effect is expected exclusively in zero limit of network concentration in real polymer networks. These features indicate that the real polymer networks with regular network structures have an explicit cross-effect of strains, which originates from some interaction between network strands (other than entanglement effect) such as nematic interaction, topological interaction, and excluded volume interaction.

New AdoMet Analogues as Tools for Enzymatic Transfer of Photo-Cross-Linkers and Capturing RNA-Protein Interactions.

PubMed

Muttach, Fabian; Mäsing, Florian; Studer, Armido; Rentmeister, Andrea

2017-05-02

Elucidation of biomolecular interactions is of utmost importance in biochemistry. Photo-cross-linking offers the possibility to precisely determine RNA-protein interactions. However, despite the inherent specificity of enzymes, approaches for site-specific introduction of photo-cross-linking moieties into nucleic acids are scarce. Methyltransferases in combination with synthetic analogues of their natural cosubstrate S-adenosyl-l-methionine (AdoMet) allow for the post-synthetic site-specific modification of biomolecules. We report on three novel AdoMet analogues bearing the most widespread photo-cross-linking moieties (aryl azide, diazirine, and benzophenone). We show that these photo-cross-linkers can be enzymatically transferred to the methyltransferase target, that is, the mRNA cap, with high efficiency. Photo-cross-linking of the resulting modified mRNAs with the cap interacting protein eIF4E was successful with aryl azide and diazirine but not benzophenone, reflecting the affinity of the modified 5' caps. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Ab initio Potential-Energy Surfaces and Electron-Spin-Exchange Cross Sections for H-O2 Interactions

NASA Technical Reports Server (NTRS)

Stallcop, James R.; Partridge, Harry; Levin, Eugene

1996-01-01

Accurate quartet- and doublet-state potential-energy surfaces for the interaction of a hydrogen atom and an oxygen molecule in their ground states have been determined from an ab initio calculation using large-basis sets and the internally contracted multireference configuration interaction method. These potential surfaces have been used to calculate the H-O2 electron-spin-exchange cross section; the square root of the cross section (in a(sub 0)), not taking into account inelastic effects, can be obtained approximately from the expressions 2.390E(sup -1/6) and 5.266-0.708 log10(E) at low and high collision energies E (in E(sub h)), respectively. These functional forms, as well as the oscillatory structure of the cross section found at high energies, are expected from the nature of the interaction energy. The mean cross section (the cross section averaged over a Maxwellian velocity distribution) agrees reasonably well with the results of measurements.

Total and partial photoneutron cross sections for Pb isotopes

NASA Astrophysics Data System (ADS)

Kondo, T.; Utsunomiya, H.; Goriely, S.; Daoutidis, I.; Iwamoto, C.; Akimune, H.; Okamoto, A.; Yamagata, T.; Kamata, M.; Itoh, O.; Toyokawa, H.; Lui, Y.-W.; Harada, H.; Kitatani, F.; Hilaire, S.; Koning, A. J.

2012-07-01

Using quasimonochromatic laser-Compton scattering γ rays, total photoneutron cross sections were measured for 206,207,208Pb near neutron threshold with a high-efficiency 4π neutron detector. Partial E1 and M1 photoneutron cross sections along with total cross sections were determined for 207,208Pb at four energies near threshold by measuring anisotropies in photoneutron emission with linearly polarized γ rays. The E1 strength dominates over the M1 strength in the neutron channel where E1 photoneutron cross sections show extra strength of the pygmy dipole resonance in 207,208Pb near the neutron threshold corresponding to 0.32%-0.42% of the Thomas-Reiche-Kuhn sum rule. Several μN2 units of B(M1)↑ strength were observed in 207,208Pb just above neutron threshold, which correspond to an M1 cross section less than 10% of the total photoneutron cross section.

In Vivo Photo-Cross-Linking to Study T3S Interactions Demonstrated Using the Yersinia pestis T3S System.

PubMed

Henderson, Thomas A; Nilles, Matthew L

2017-01-01

Cross-linking of proteins is effective in determining protein-protein interactions. The use of photo-cross-linkers was developed to study protein interactions in several manners. One method involved the incorporation of photo-activatable cross-linking groups into chemically synthesized peptides. A second approach relies on incorporation of photo-activatable cross-linking groups into proteins using tRNAs with chemically bound photo-activatable amino acids with suppressor tRNAs translational systems to incorporate the tags into specific sites. A third system was made possible by the development of photoreactive amino acids that use the normal cellular tRNAs and aminoacyl tRNA synthetases. In this method, the third system is used to demonstrate its utility for the study of T3S system interactions. This method describes how two photo-activatable amino acids, photo-methionine and photo-leucine, that use the normal cellular machinery are incorporated into Yersinia pestis and used to study interactions in the T3S system. To demonstrate the system, the method was used to cross-link the T3S regulatory proteins LcrG and LcrV.

Interactions of relativistic 36Ar and 40Ar nuclei in hydrogen: Isotopic production cross sections

NASA Astrophysics Data System (ADS)

Knott, C. N.; Albergo, S.; Caccia, Z.; Chen, C.-X.; Costa, S.; Crawford, H. J.; Cronqvist, M.; Engelage, J.; Greiner, L.; Guzik, T. G.; Insolia, A.; Lindstrom, P. J.; Mitchell, J. W.; Potenza, R.; Russo, G. V.; Soutoul, A.; Testard, O.; Tull, C. E.; Tuvé, C.; Waddington, C. J.; Webber, W. R.; Wefel, J. P.

1997-07-01

The interactions of 36Ar projectile nuclei with energies of 361, 546, and 765 MeV/nucleon and 40Ar nuclei with 352 MeV/nucleon, have been studied in a liquid-hydrogen target as part of a program to study interactions of relevance to the problem of cosmic-ray propagation in the interstellar medium. We have measured the cross sections for the production of isotopic fragments of the projectile nuclei in these interactions. The variations of these cross sections with mass, charge, and energy, are examined for insights into any systematic features of this type of fragmentation reaction that might aid predictions of other, unmeasured cross sections. These cross sections are also compared with the values derived from the most commonly used prediction techniques. It is suggested that these techniques could be improved by taking account of the systematic features identified here.

Health Care Professionals’ Understandings of Cross-Cultural Interaction in End-of-Life Care: A Focus Group Study

PubMed Central

Torres, Sandra; Ågård, Pernilla

2016-01-01

Objective The academic debate on cross-cultural interaction within the context of end-of-life care takes for granted that this interaction is challenging. However, few empirical studies have actually focused on what health care professionals think about this interaction. This study aimed to explore health care professionals’ understandings of cross-cultural interaction during end-of-life care. Methods Sixty end-of-life care professionals were recruited from eleven care units in Sweden to take part in focus group interviews. These interviews were analyzed using qualitative content analysis. Results The health care professionals interviewed talked about cross-cultural interaction in end-of-life care as interaction that brings about uncertainty, stress and frustration even though they had limited experience of this type of interaction. The focus group discussions brought attention to four specific challenges that they expected to meet when they care for patients with migrant backgrounds since they took for granted that they would have an ethno-cultural background that is different to their own. These challenges had to do with communication barriers, ‘unusual’ emotional and pain expressions, the expectation that these patients’ families would be ‘different’ and the anticipation that these patients and their families lack knowledge. At the core of the challenges in question is the idea that cross-cultural interaction means meeting “the unknown”. In addition, the end-of-life care professionals interviewed talked about patients whose backgrounds they did not share in homogenizing terms. It is against this backdrop that they worried about their ability to provide end-of-life care that is individualized enough to meet the needs of these patients. Conclusions The study suggests that end-of-life care professionals who regard cross-cultural interaction in this manner could face actual challenges when caring for patients whose backgrounds they regard as “the unknown” since they anticipate a variety of challenges and do not seem confident enough that they can provide good quality care when cross-cultural interaction is at stake. PMID:27880814

The Formation Mechanism of Hydrogels.

PubMed

Lu, Liyan; Yuan, Shiliang; Wang, Jing; Shen, Yun; Deng, Shuwen; Xie, Luyang; Yang, Qixiang

2017-06-12

Hydrogels are degradable polymeric networks, in which cross-links play a vital role in structure formation and degradation. Cross-linking is a stabilization process in polymer chemistry that leads to the multi-dimensional extension of polymeric chains, resulting in network structures. By cross-linking, hydrogels are formed into stable structures that differ from their raw materials. Generally, hydrogels can be prepared from either synthetic or natural polymers. Based on the types of cross-link junctions, hydrogels can be categorized into two groups: the chemically cross-linked and the physically cross-linked. Chemically cross-linked gels have permanent junctions, in which covalent bonds are present between different polymer chains, thus leading to excellent mechanical strength. Although chemical cross-linking is a highly resourceful method for the formation of hydrogels, the cross-linkers used in hydrogel preparation should be extracted from the hydrogels before use, due to their reported toxicity, while, in physically cross-linked gels, dissolution is prevented by physical interactions, such as ionic interactions, hydrogen bonds or hydrophobic interactions. Physically cross-linked methods for the preparation of hydrogels are the alternate solution for cross-linker toxicity. Both methods will be discussed in this essay. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Can We Become Friends? Students' Cross-Racial Interaction in Post-Apartheid South African Higher Education

ERIC Educational Resources Information Center

Wertheim, Samantha Shapses

2014-01-01

This article investigates and documents how undergraduate students in South Africa make meaning of cross-racial interaction on the college campus in the post-apartheid era. Additionally, it explores how students perceive that interactions with diverse peers have shifted since apartheid, and how these interactions are indicative of the larger…

Total reaction cross sections in CEM and MCNP6 at intermediate energies

DOE PAGES

Kerby, Leslie M.; Mashnik, Stepan G.

2015-05-14

Accurate total reaction cross section models are important to achieving reliable predictions from spallation and transport codes. The latest version of the Cascade Exciton Model (CEM) as incorporated in the code CEM03.03, and the Monte Carlo N-Particle transport code (MCNP6), both developed at Los Alamos National Laboratory (LANL), each use such cross sections. Having accurate total reaction cross section models in the intermediate energy region (50 MeV to 5 GeV) is very important for different applications, including analysis of space environments, use in medical physics, and accelerator design, to name just a few. The current inverse cross sections used inmore » the preequilibrium and evaporation stages of CEM are based on the Dostrovsky et al. model, published in 1959. Better cross section models are now available. Implementing better cross section models in CEM and MCNP6 should yield improved predictions for particle spectra and total production cross sections, among other results.« less

Total reaction cross sections in CEM and MCNP6 at intermediate energies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kerby, Leslie M.; Mashnik, Stepan G.

Accurate total reaction cross section models are important to achieving reliable predictions from spallation and transport codes. The latest version of the Cascade Exciton Model (CEM) as incorporated in the code CEM03.03, and the Monte Carlo N-Particle transport code (MCNP6), both developed at Los Alamos National Laboratory (LANL), each use such cross sections. Having accurate total reaction cross section models in the intermediate energy region (50 MeV to 5 GeV) is very important for different applications, including analysis of space environments, use in medical physics, and accelerator design, to name just a few. The current inverse cross sections used inmore » the preequilibrium and evaporation stages of CEM are based on the Dostrovsky et al. model, published in 1959. Better cross section models are now available. Implementing better cross section models in CEM and MCNP6 should yield improved predictions for particle spectra and total production cross sections, among other results.« less

ST5 Observations of the Imbalance of Region 1 and 2 Field-Aligned Currents and Its Implication to the Cross-Polar Cap Pedersen Currents

NASA Technical Reports Server (NTRS)

Le, Guan; Slavin, J. A.; Strangeway, Robert

2011-01-01

In this study, we use the in-situ magnetic field observations from Space Technology 5 mission to quantify the imbalance of Region 1 (R1) and Region 2 (R2) currents. During the three-month duration of the ST5 mission, geomagnetic conditions range from quiet to moderately active. We find that the R1 current intensity is consistently stronger than the R2 current intensity both for the dawnside and the duskside large-scale field-aligned current system. The net currents flowing into (out of) the ionosphere in the dawnside (duskside) are in the order of 5% of the total R1 currents. We also find that the net currents flowing into or out of the ionosphere are controlled by the solar wind-magnetosphere interaction in the same way as the field-aligned currents themselves are. Since the net currents due to the imbalance of the R1 and R2 currents require that their closure currents flow across the polar cap from dawn to dusk as Pedersen currents, our results indicate that the total amount of the cross-polar cap Pedersen currents is in the order of 0.1 MA. This study, although with a very limited dataset, is one of the first attempts to quantify the cross-polar cap Pedersen currents. Given the importance of the Joule heating due to Pedersen currents to the high-latitude ionospheric electrodynamics, quantifying the cross-polar cap Pedersen currents and associated Joule heating is needed for developing models of the magnetosphere-ionosphere coupling.

ST5 Observations of the Imbalance of Region 1 and 2 Field-Aligned Currents and its Implication to the Cross-Polar Cap Pedersen Currents

NASA Technical Reports Server (NTRS)

Le, Guan; Slavin, J. A.; Strangeway, Robert

2010-01-01

In this study, we use the in-situ magnetic field observations from Space Technology 5 mission to quantify the imbalance of Region 1 (R1) and Region 2 (R2) currents. During the three-month duration of the ST5 mission, geomagnetic conditions range from quiet to moderately active. We find that the R1 current intensity is consistently stronger than the R2 current intensity both for the dawnside and the duskside large-scale field-aligned current system. The net currents flowing into (out of) the ionosphere in the dawnside (duskside) are in the order of 5% of the total R1 currents. We also find that the net currents flowing into or out of the ionosphere are controlled by the solar windmagnetosphere interaction in the same way as the field-aligned currents themselves are. Since the net currents due to the imbalance of the R1 and R2 currents require that their closure currents flow across the polar cap from dawn to dusk as Pedersen currents, our results indicate that the total amount of the cross-polar cap Pedersen currents is in the order of approximately 0.1 MA. This study, although with a very limited dataset, is one of the first attempts to quantify the cross-polar cap Pedersen currents. Given the importance of the Joule heating due to Pedersen currents to the high-latitude ionospheric electrodynamics, quantifying the cross-polar cap Pedersen currents and associated Joule heating is needed for developing models of the magnetosphere-ionosphere coupling.

Measurement of the Charged-Current Quasi-Elastic Cross-Section for Electron Neutrinos on a Hydrocarbon Target

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wolcott, Jeremy

2016-01-01

Appearance-type neutrino oscillation experiments, which observe the transition from muon neutrinos to electron neutrinos, promise to help answer some of the fundamental questions surrounding physics in the post-Standard-Model era. Because they wish to observe the interactions of electron neutrinos in their detectors, and because the power of current results is typically limited by their systematic uncertainties, these experiments require precise estimates of the cross-section for electron neutrino interactions. Of particular interest is the charged-current quasi-elastic (CCQE) process, which gures signi cantly in the composition of the reactions observed at the far detector. However, no experimental measurements of this crosssection currentlymore » exist for electron neutrinos; instead, current experiments typically work from the abundance of muon neutrino CCQE cross-section data and apply corrections from theoretical arguments to obtain a prediction for electron neutrinos. Veri cation of these predictions is challenging due to the di culty of constructing an electron neutrino beam, but the advent of modern high-intensity muon neutrino beams|together with the percent-level electron neutrino impurity inherent in these beams| nally presents the opportunity to make such a measurement. We report herein the rst-ever measurement of a cross-section for an exclusive state in electron neutrino scattering, which was made using the MINER A detector in the NuMI neutrino beam at Fermilab. We present the electron neutrino CCQE di erential cross-sections, which are averaged over neutrinos of energies 1-10 GeV (with mean energy of about 3 GeV), in terms of various kinematic variables: nal-state electron angle, nal-state electron energy, and the square of the fourmomentum transferred to the nucleus by the neutrino , Q 2. We also provide a total cross-section vs. neutrino energy. While our measurement of this process is found to be in agreement with the predictions of the GENIE event generator, we also report on an unpredicted photon-like process we observe in a similar kinematic regime. The absence of this process from models for neutrino interactions is a potential stumbling block for future on-axis neutrino oscillation experiments. We include kinematic and particle species identi cation characterizations which can be used in building models to help address this shortcoming.« less

From metabolism to ecology: cross-feeding interactions shape the balance between polymicrobial conflict and mutualism

PubMed Central

Estrela, Sylvie; Trisos, Christopher H.; Brown, Sam P.

2012-01-01

Polymicrobial interactions are widespread in nature, and play a major role in maintaining human health and ecosystems. Whenever one organism uses metabolites produced by another organism as energy or nutrient sources, this is called cross-feeding. The ecological outcomes of cross-feeding interactions are poorly understood and potentially diverse: mutualism, competition, exploitation or commensalism. A major reason for this uncertainty is the lack of theoretical approaches linking microbial metabolism to microbial ecology. To address this issue, we explore the dynamics of a one-way interspecific cross-feeding interaction, in which food can be traded for a service (detoxification). Our results show that diverse ecological interactions (competition, mutualism, exploitation) can emerge from this simple cross-feeding interaction, and can be predicted by the metabolic, demographic and environmental parameters that govern the balance of the costs and benefits of association. In particular, our model predicts stronger mutualism for intermediate by-product toxicity because the resource-service exchange is constrained to the service being neither too vital (high toxicity impairs resource provision) nor dispensable (low toxicity reduces need for service). These results support the idea that bridging microbial ecology and metabolism is a critical step towards a better understanding of the factors governing the emergence and dynamics of polymicrobial interactions. PMID:23070318

Evaluation of community pharmacists' knowledge and awareness of food-drug interactions in Palestine.

PubMed

Radwan, Asma; Sweileh, Anwar; Shraim, We'am; Hroub, Amr; Elaraj, Josephean; Shraim, Naser

2018-05-02

Background Food-drug interactions can produce undesirable outcomes during the therapy process. The pharmacist is responsible for providing patients counseling about common food-drug interactions. Knowledge of such interactions is important to avoid their occurrence. Objective This study aimed to assess the knowledge and awareness of community pharmacists about common food-drug interactions. Setting Pharmacists working in community pharmacies across Northern Palestine. Method This is a cross-sectional study, which involved a convenience sample of 259 pharmacists working in community pharmacies in Palestine. A self-administered questionnaire consisted of 29 questions (mainly yes/no questions) was used to assess pharmacists' knowledge towards the most common and clinically significant interactions between food and medicines. Main outcome measure Pharmacists' issues related to the knowledge of food drug interactions were evaluated. Results A total of 320 questionnaires were distributed of which 259 were completed providing a response rate 80.9%. One pharmacist from each community pharmacy was asked to complete the questionnaire. The overall knowledge score of food-drug interactions for the pharmacists was 17.9 (61.7%) out of a possible maximum of 29. The pharmacists surveyed in this study have demonstrated good knowledge of some interactions; but poor knowledge of others. Conclusion Pharmacists' knowledge about common food-drug interactions is inadequate. These findings support the need for training and educational courses for pharmacists regarding food-drug interactions.

Adverse events caused by potential drug-drug interactions in an intensive care unit of a teaching hospital

PubMed Central

Alvim, Mariana Macedo; da Silva, Lidiane Ayres; Leite, Isabel Cristina Gonçalves; Silvério, Marcelo Silva

2015-01-01

Objective To evaluate the incidence of potential drug-drug interactions in an intensive care unit of a hospital, focusing on antimicrobial drugs. Methods This cross-sectional study analyzed electronic prescriptions of patients admitted to the intensive care unit of a teaching hospital between January 1 and March 31, 2014 and assessed potential drug-drug interactions associated with antimicrobial drugs. Antimicrobial drug consumption levels were expressed in daily doses per 100 patient-days. The search and classification of the interactions were based on the Micromedex® system. Results The daily prescriptions of 82 patients were analyzed, totaling 656 prescriptions. Antimicrobial drugs represented 25% of all prescription drugs, with meropenem, vancomycin and ceftriaxone being the most prescribed medications. According to the approach of daily dose per 100 patient-days, the most commonly used antimicrobial drugs were cefepime, meropenem, sulfamethoxazole + trimethoprim and ciprofloxacin. The mean number of interactions per patient was 2.6. Among the interactions, 51% were classified as contraindicated or significantly severe. Highly significant interactions (clinical value 1 and 2) were observed with a prevalence of 98%. Conclusion The current study demonstrated that antimicrobial drugs are frequently prescribed in intensive care units and present a very high number of potential drug-drug interactions, with most of them being considered highly significant. PMID:26761473

Neutron total cross section measurement at WNR. [215 to 250 MeV experimental techniques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lisowski, P.W.; Moore, M.S.; Morgan, G.L.

1979-01-01

The techniques involved in measuring fast-neutron total cross sections at the Weapons Neutron Facility (WNR) of the Los Alamos Scientific Laboratory are described. Results of total cross section measurements on natural carbon covering the range 2.5 to 250 MeV are presented. 16 references.

Interactive effects of multiple stressors revealed by sequencing total (DNA) and active (RNA) components of experimental sediment microbial communities.

PubMed

Birrer, Simone C; Dafforn, Katherine A; Simpson, Stuart L; Kelaher, Brendan P; Potts, Jaimie; Scanes, Peter; Johnston, Emma L

2018-05-15

Coastal waterways are increasingly exposed to multiple stressors, e.g. contaminants that can be delivered via pulse or press exposures. Therefore, it is crucial that ecological impacts can be differentiated among stressors to manage ecosystem threats. We investigated microbial community development in sediments exposed to press and pulse stressors. Press exposures were created with in situ mesocosm sediments containing a range of 'metal' concentrations (sediment contaminated with multiple metal(loid)s) and organic enrichment (fertiliser), while the pulse exposure was simulated by a single dose of organic fertiliser. All treatments and exposure concentrations were crossed in a fully factorial field experiment. We used amplicon sequencing to compare the sensitivity of the 1) total (DNA) and active (RNA) component of 2) bacterial (16S rRNA) and eukaryotic (18S rRNA) communities to contaminant exposures. Overall microbial community change was greater when exposed to press than pulse stressors, with the bacterial community responding more strongly than the eukaryotes. The total bacterial community represents a more time-integrated measure of change and proved to be more sensitive to multiple stressors than the active community. Metals and organic enrichment treatments interacted such that the effect of metals was weaker when the sediment was organically enriched. Taxa-level analyses revealed that press enrichment resulted in potential functional changes, mainly involving nitrogen cycling. Furthermore, enrichment generally reduced the abundance of active eukaryotes in the sediment. As well as demonstrating interactive impacts of metals and organic enrichment, this study highlights the sensitivity of next-generation sequencing for ecosystem biomonitoring of interacting stressors and identifies opportunities for more targeted application. Copyright © 2018 Elsevier B.V. All rights reserved.

Robust cross-links in molluscan adhesive gels: Testing for contributions from hydrophobic and electrostatic interactions

PubMed Central

Smith, A.M.; Robinson, T. M.; Salt, M. D.; Hamilton, K. S.; Silvia, B. E.; Blasiak, R.

2009-01-01

The cross-linking interactions that provide cohesive strength to molluscan adhesive gels were investigated. Metal-based interactions have been shown to play an important role in the glue of the slug Arion subfuscus (Draparnaud), but other types of interactions may also contribute to the glue's strength and their role has not been investigated. This study shows that treatments that normally disrupt hydrophobic or electrostatic interactions have little to no effect on the slug glue. High salt concentrations and non-ionic detergent do not affect the solubility of the proteins in the glue or the ability of the glue proteins to stiffen gels. In contrast, metal chelation markedly disrupts the gel. Experiments with gel filtration chromatography identify a 40 kDa protein that is a central component of the cross-links in the glue. This 40 kDa protein forms robust macromolecular aggregations that are stable even in the presence of high concentrations of salt, non-ionic detergent, urea or metal chelators. Metal chelation during glue secretion, however, may block some of these cross-links. Such robust, non-specific interactions in an aqueous environment are highly unusual for hydrogels and reflect an intriguing cross-linking mechanism. PMID:18952190

Robust cross-links in molluscan adhesive gels: testing for contributions from hydrophobic and electrostatic interactions.

PubMed

Smith, A M; Robinson, T M; Salt, M D; Hamilton, K S; Silvia, B E; Blasiak, R

2009-02-01

The cross-linking interactions that provide cohesive strength to molluscan adhesive gels were investigated. Metal-based interactions have been shown to play an important role in the glue of the slug Arion subfuscus (Draparnaud), but other types of interactions may also contribute to the glue's strength and their role has not been investigated. This study shows that treatments that normally disrupt hydrophobic or electrostatic interactions have little to no effect on the slug glue. High salt concentrations and non-ionic detergent do not affect the solubility of the proteins in the glue or the ability of the glue proteins to stiffen gels. In contrast, metal chelation markedly disrupts the gel. Experiments with gel filtration chromatography identify a 40 kDa protein that is a central component of the cross-links in the glue. This 40 kDa protein forms robust macromolecular aggregations that are stable even in the presence of high concentrations of salt, non-ionic detergent, urea or metal chelators. Metal chelation during glue secretion, however, may block some of these cross-links. Such robust, non-specific interactions in an aqueous environment are highly unusual for hydrogels and reflect an intriguing cross-linking mechanism.

Soft-Rotator Coupled Channels Global Optical Potential for A=24-122 Mass Region Nuclides up to 200-MeV Incident Nucleon Energies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Soukhovitski, Efrem Sh.; Chiba, Satoshi; Lee, Jeong-Yeon

2005-05-24

A coupled-channels optical model with a coupling scheme based on nuclear wave functions of the soft-rotator model was applied to analyze experimental nucleon-nucleus interaction data for even-even nuclides with mass number A=24-122. We found that all the available data (total cross sections, angular distributions of elastically and inelastically scattered nucleons, and reaction cross sections) for these nuclides can be described to a good accuracy using an optical potential having smooth dependencies of potential values, radii, and diffuseness on the mass number. The individual properties of the target nuclides are accounted for by individuality of the nuclear Hamiltonian parameters, adjusted tomore » reproduce the low-lying collective level structure, Fermi energies, and deformation parameters.« less

Untangling Brain-Wide Dynamics in Consciousness by Cross-Embedding

PubMed Central

Tajima, Satohiro; Yanagawa, Toru; Fujii, Naotaka; Toyoizumi, Taro

2015-01-01

Brain-wide interactions generating complex neural dynamics are considered crucial for emergent cognitive functions. However, the irreducible nature of nonlinear and high-dimensional dynamical interactions challenges conventional reductionist approaches. We introduce a model-free method, based on embedding theorems in nonlinear state-space reconstruction, that permits a simultaneous characterization of complexity in local dynamics, directed interactions between brain areas, and how the complexity is produced by the interactions. We demonstrate this method in large-scale electrophysiological recordings from awake and anesthetized monkeys. The cross-embedding method captures structured interaction underlying cortex-wide dynamics that may be missed by conventional correlation-based analysis, demonstrating a critical role of time-series analysis in characterizing brain state. The method reveals a consciousness-related hierarchy of cortical areas, where dynamical complexity increases along with cross-area information flow. These findings demonstrate the advantages of the cross-embedding method in deciphering large-scale and heterogeneous neuronal systems, suggesting a crucial contribution by sensory-frontoparietal interactions to the emergence of complex brain dynamics during consciousness. PMID:26584045

Cooperative Games as an Intervention to Promote Cross-racial Acceptance.

ERIC Educational Resources Information Center

Rogers, Marian; And Others

1981-01-01

More cross-racial interaction was found among boys because they participate in more team sports. Cooperative games have a strong potential for facilitating social acceptance among desegregated elementary school girls. Observations of cross-racial prosocial and antagonistic interactions revealed the practical value of games for increasing…

Single and double capture in F9+ + Ar collisions: Comparison of total capture with capture occurring from the Ar K shell

NASA Astrophysics Data System (ADS)

La Mantia, David; Kumara, Nuwan; Kayani, Asghar; Simon, Anna; Tanis, John

2016-05-01

Total cross sections for single and double capture, as well as the corresponding cross sections for capture resulting in the emission of an Ar K x ray, were measured. This work was performed at Western Michigan University with the use of the tandem Van de Graaff accelerator. A 45 MeV beam of fully-stripped fluorine ions was collided with argon gas molecules in a differentially pumped cell. Surface barrier detectors were used to observe the charge changed projectiles and a Si(Li) x-ray detector, placed at 90o to the incident beam, were used to measure coincidences with Ar K x rays. The total capture cross sections are compared to previously measured cross sections in the existing literature. The coincidence cross sections, considerably smaller than the total cross sections, are found to be nearly equal for single and double capture in contrast to the total cross sections, which vary by about an order of magnitude. Possible reasons for this behavior are discussed. Supported in part by the NSF.

Measurement of inclusive and differential cross sections in the H → ZZ * → 4 ℓ decay channel in pp collisions at √{s}=13 TeV with the ATLAS detector

NASA Astrophysics Data System (ADS)

Aaboud, M.; Aad, G.; Abbott, B.; Abdinov, O.; Abeloos, B.; Abidi, S. H.; AbouZeid, O. S.; Abraham, N. L.; Abramowicz, H.; Abreu, H.; Abreu, R.; Abulaiti, Y.; Acharya, B. S.; Adachi, S.; Adamczyk, L.; Adelman, J.; Adersberger, M.; Adye, T.; Affolder, A. A.; Afik, Y.; Agatonovic-Jovin, T.; Agheorghiesei, C.; Aguilar-Saavedra, J. A.; Ahlen, S. P.; Ahmadov, F.; Aielli, G.; Akatsuka, S.; Akerstedt, H.; Åkesson, T. P. A.; Akilli, E.; Akimov, A. V.; Alberghi, G. L.; Albert, J.; Albicocco, P.; Alconada Verzini, M. J.; Alderweireldt, S. C.; Aleksa, M.; Aleksandrov, I. N.; Alexa, C.; Alexander, G.; Alexopoulos, T.; Alhroob, M.; Ali, B.; Aliev, M.; Alimonti, G.; Alison, J.; Alkire, S. P.; Allbrooke, B. M. M.; Allen, B. W.; Allport, P. P.; Aloisio, A.; Alonso, A.; Alonso, F.; Alpigiani, C.; Alshehri, A. A.; Alstaty, M. I.; Alvarez Gonzalez, B.; Álvarez Piqueras, D.; Alviggi, M. G.; Amadio, B. T.; Amaral Coutinho, Y.; Amelung, C.; Amidei, D.; Amor Dos Santos, S. P.; Amoroso, S.; Amundsen, G.; Anastopoulos, C.; Ancu, L. S.; Andari, N.; Andeen, T.; Anders, C. F.; Anders, J. K.; Anderson, K. J.; Andreazza, A.; Andrei, V.; Angelidakis, S.; Angelozzi, I.; Angerami, A.; Anisenkov, A. V.; Anjos, N.; Annovi, A.; Antel, C.; Antonelli, M.; Antonov, A.; Antrim, D. J.; Anulli, F.; Aoki, M.; Aperio Bella, L.; Arabidze, G.; Arai, Y.; Araque, J. P.; Araujo Ferraz, V.; Arce, A. T. H.; Ardell, R. E.; Arduh, F. A.; Arguin, J.-F.; Argyropoulos, S.; Arik, M.; Armbruster, A. J.; Armitage, L. J.; Arnaez, O.; Arnold, H.; Arratia, M.; Arslan, O.; Artamonov, A.; Artoni, G.; Artz, S.; Asai, S.; Asbah, N.; Ashkenazi, A.; Asquith, L.; Assamagan, K.; Astalos, R.; Atkinson, M.; Atlay, N. B.; Augsten, K.; Avolio, G.; Axen, B.; Ayoub, M. K.; Azuelos, G.; Baas, A. E.; Baca, M. J.; Bachacou, H.; Bachas, K.; Backes, M.; Bagnaia, P.; Bahmani, M.; Bahrasemani, H.; Baines, J. T.; Bajic, M.; Baker, O. K.; Baldin, E. M.; Balek, P.; Balli, F.; Balunas, W. K.; Banas, E.; Bandyopadhyay, A.; Banerjee, Sw.; Bannoura, A. A. E.; Barak, L.; Barberio, E. L.; Barberis, D.; Barbero, M.; Barillari, T.; Barisits, M.-S.; Barkeloo, J. T.; Barklow, T.; Barlow, N.; Barnes, S. L.; Barnett, B. M.; Barnett, R. M.; Barnovska-Blenessy, Z.; Baroncelli, A.; Barone, G.; Barr, A. J.; Barranco Navarro, L.; Barreiro, F.; Barreiro Guimarães da Costa, J.; Bartoldus, R.; Barton, A. E.; Bartos, P.; Basalaev, A.; Bassalat, A.; Bates, R. L.; Batista, S. J.; Batley, J. R.; Battaglia, M.; Bauce, M.; Bauer, F.; Bawa, H. S.; Beacham, J. B.; Beattie, M. D.; Beau, T.; Beauchemin, P. H.; Bechtle, P.; Beck, H. P.; Beck, H. C.; Becker, K.; Becker, M.; Becot, C.; Beddall, A. J.; Beddall, A.; Bednyakov, V. A.; Bedognetti, M.; Bee, C. P.; Beermann, T. A.; Begalli, M.; Begel, M.; Behr, J. K.; Bell, A. S.; Bella, G.; Bellagamba, L.; Bellerive, A.; Bellomo, M.; Belotskiy, K.; Beltramello, O.; Belyaev, N. 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V.; Dehghanian, N.; Deigaard, I.; Del Gaudio, M.; Del Peso, J.; Delgove, D.; Deliot, F.; Delitzsch, C. M.; Dell'Acqua, A.; Dell'Asta, L.; Dell'Orso, M.; Della Pietra, M.; della Volpe, D.; Delmastro, M.; Delporte, C.; Delsart, P. A.; DeMarco, D. A.; Demers, S.; Demichev, M.; Demilly, A.; Denisov, S. P.; Denysiuk, D.; Derendarz, D.; Derkaoui, J. E.; Derue, F.; Dervan, P.; Desch, K.; Deterre, C.; Dette, K.; Devesa, M. R.; Deviveiros, P. O.; Dewhurst, A.; Dhaliwal, S.; Di Bello, F. A.; Di Ciaccio, A.; Di Ciaccio, L.; Di Clemente, W. K.; Di Donato, C.; Di Girolamo, A.; Di Girolamo, B.; Di Micco, B.; Di Nardo, R.; Di Petrillo, K. F.; Di Simone, A.; Di Sipio, R.; Di Valentino, D.; Diaconu, C.; Diamond, M.; Dias, F. A.; Diaz, M. A.; Diehl, E. B.; Dietrich, J.; Díez Cornell, S.; Dimitrievska, A.; Dingfelder, J.; Dita, P.; Dita, S.; Dittus, F.; Djama, F.; Djobava, T.; Djuvsland, J. I.; do Vale, M. A. B.; Dobos, D.; Dobre, M.; Doglioni, C.; Dolejsi, J.; Dolezal, Z.; Donadelli, M.; Donati, S.; Dondero, P.; Donini, J.; Dopke, J.; Doria, A.; Dova, M. T.; Doyle, A. T.; Drechsler, E.; Dris, M.; Du, Y.; Duarte-Campderros, J.; Dubreuil, A.; Duchovni, E.; Duckeck, G.; Ducourthial, A.; Ducu, O. A.; Duda, D.; Dudarev, A.; Dudder, A. Chr.; Duffield, E. M.; Duflot, L.; Dührssen, M.; Dumancic, M.; Dumitriu, A. E.; Duncan, A. K.; Dunford, M.; Duran Yildiz, H.; Düren, M.; Durglishvili, A.; Duschinger, D.; Dutta, B.; Duvnjak, D.; Dyndal, M.; Dziedzic, B. S.; Eckardt, C.; Ecker, K. M.; Edgar, R. C.; Eifert, T.; Eigen, G.; Einsweiler, K.; Ekelof, T.; El Kacimi, M.; El Kosseifi, R.; Ellajosyula, V.; Ellert, M.; Elles, S.; Ellinghaus, F.; Elliot, A. A.; Ellis, N.; Elmsheuser, J.; Elsing, M.; Emeliyanov, D.; Enari, Y.; Endner, O. C.; Ennis, J. S.; Erdmann, J.; Ereditato, A.; Ernst, M.; Errede, S.; Escalier, M.; Escobar, C.; Esposito, B.; Estrada Pastor, O.; Etienvre, A. I.; Etzion, E.; Evans, H.; Ezhilov, A.; Ezzi, M.; Fabbri, F.; Fabbri, L.; Fabiani, V.; Facini, G.; Fakhrutdinov, R. M.; Falciano, S.; Falla, R. J.; Faltova, J.; Fang, Y.; Fanti, M.; Farbin, A.; Farilla, A.; Farina, C.; Farina, E. M.; Farooque, T.; Farrell, S.; Farrington, S. M.; Farthouat, P.; Fassi, F.; Fassnacht, P.; Fassouliotis, D.; Faucci Giannelli, M.; Favareto, A.; Fawcett, W. J.; Fayard, L.; Fedin, O. L.; Fedorko, W.; Feigl, S.; Feligioni, L.; Feng, C.; Feng, E. J.; Fenton, M. J.; Fenyuk, A. B.; Feremenga, L.; Fernandez Martinez, P.; Fernandez Perez, S.; Ferrando, J.; Ferrari, A.; Ferrari, P.; Ferrari, R.; Ferreira de Lima, D. E.; Ferrer, A.; Ferrere, D.; Ferretti, C.; Fiedler, F.; Filipčič, A.; Filipuzzi, M.; Filthaut, F.; Fincke-Keeler, M.; Finelli, K. D.; Fiolhais, M. C. N.; Fiorini, L.; Fischer, A.; Fischer, C.; Fischer, J.; Fisher, W. C.; Flaschel, N.; Fleck, I.; Fleischmann, P.; Fletcher, R. R. M.; Flick, T.; Flierl, B. M.; Flores Castillo, L. R.; Flowerdew, M. J.; Forcolin, G. T.; Formica, A.; Förster, F. A.; Forti, A.; Foster, A. G.; Fournier, D.; Fox, H.; Fracchia, S.; Francavilla, P.; Franchini, M.; Franchino, S.; Francis, D.; Franconi, L.; Franklin, M.; Frate, M.; Fraternali, M.; Freeborn, D.; Fressard-Batraneanu, S. M.; Freund, B.; Froidevaux, D.; Frost, J. A.; Fukunaga, C.; Fusayasu, T.; Fuster, J.; Gabizon, O.; Gabrielli, A.; Gabrielli, A.; Gach, G. P.; Gadatsch, S.; Gadomski, S.; Gagliardi, G.; Gagnon, L. G.; Galea, C.; Galhardo, B.; Gallas, E. J.; Gallop, B. J.; Gallus, P.; Galster, G.; Gan, K. K.; Ganguly, S.; Gao, Y.; Gao, Y. S.; Garay Walls, F. M.; García, C.; García Navarro, J. E.; García Pascual, J. A.; Garcia-Sciveres, M.; Gardner, R. W.; Garelli, N.; Garonne, V.; Gascon Bravo, A.; Gasnikova, K.; Gatti, C.; Gaudiello, A.; Gaudio, G.; Gavrilenko, I. L.; Gay, C.; Gaycken, G.; Gazis, E. N.; Gee, C. N. P.; Geisen, J.; Geisen, M.; Geisler, M. P.; Gellerstedt, K.; Gemme, C.; Genest, M. H.; Geng, C.; Gentile, S.; Gentsos, C.; George, S.; Gerbaudo, D.; Geßner, G.; Ghasemi, S.; Ghneimat, M.; Giacobbe, B.; Giagu, S.; Giangiacomi, N.; Giannetti, P.; Gibson, S. M.; Gignac, M.; Gilchriese, M.; Gillberg, D.; Gilles, G.; Gingrich, D. M.; Giordani, M. P.; Giorgi, F. M.; Giraud, P. F.; Giromini, P.; Giugliarelli, G.; Giugni, D.; Giuli, F.; Giuliani, C.; Giulini, M.; Gjelsten, B. K.; Gkaitatzis, S.; Gkialas, I.; Gkougkousis, E. L.; Gkountoumis, P.; Gladilin, L. K.; Glasman, C.; Glatzer, J.; Glaysher, P. C. F.; Glazov, A.; Goblirsch-Kolb, M.; Godlewski, J.; Goldfarb, S.; Golling, T.; Golubkov, D.; Gomes, A.; Gonçalo, R.; Goncalves Gama, R.; Goncalves Pinto Firmino Da Costa, J.; Gonella, G.; Gonella, L.; Gongadze, A.; González de la Hoz, S.; Gonzalez-Sevilla, S.; Goossens, L.; Gorbounov, P. A.; Gordon, H. A.; Gorelov, I.; Gorini, B.; Gorini, E.; Gorišek, A.; Goshaw, A. T.; Gössling, C.; Gostkin, M. I.; Gottardo, C. A.; Goudet, C. R.; Goujdami, D.; Goussiou, A. G.; Govender, N.; Gozani, E.; Grabowska-Bold, I.; Gradin, P. O. J.; Gramling, J.; Gramstad, E.; Grancagnolo, S.; Gratchev, V.; Gravila, P. M.; Gray, C.; Gray, H. M.; Greenwood, Z. D.; Grefe, C.; Gregersen, K.; Gregor, I. M.; Grenier, P.; Grevtsov, K.; Griffiths, J.; Grillo, A. A.; Grimm, K.; Grinstein, S.; Gris, Ph.; Grivaz, J.-F.; Groh, S.; Gross, E.; Grosse-Knetter, J.; Grossi, G. C.; Grout, Z. J.; Grummer, A.; Guan, L.; Guan, W.; Guenther, J.; Guescini, F.; Guest, D.; Gueta, O.; Gui, B.; Guido, E.; Guillemin, T.; Guindon, S.; Gul, U.; Gumpert, C.; Guo, J.; Guo, W.; Guo, Y.; Gupta, R.; Gupta, S.; Gurbuz, S.; Gustavino, G.; Gutelman, B. J.; Gutierrez, P.; Gutierrez Ortiz, N. G.; Gutschow, C.; Guyot, C.; Guzik, M. P.; Gwenlan, C.; Gwilliam, C. B.; Haas, A.; Haber, C.; Hadavand, H. K.; Haddad, N.; Hadef, A.; Hageböck, S.; Hagihara, M.; Hakobyan, H.; Haleem, M.; Haley, J.; Halladjian, G.; Hallewell, G. D.; Hamacher, K.; Hamal, P.; Hamano, K.; Hamilton, A.; Hamity, G. N.; Hamnett, P. G.; Han, L.; Han, S.; Hanagaki, K.; Hanawa, K.; Hance, M.; Haney, B.; Hanke, P.; Hansen, J. B.; Hansen, J. D.; Hansen, M. C.; Hansen, P. H.; Hara, K.; Hard, A. S.; Harenberg, T.; Hariri, F.; Harkusha, S.; Harrison, P. F.; Hartmann, N. M.; Hasegawa, Y.; Hasib, A.; Hassani, S.; Haug, S.; Hauser, R.; Hauswald, L.; Havener, L. B.; Havranek, M.; Hawkes, C. M.; Hawkings, R. J.; Hayakawa, D.; Hayden, D.; Hays, C. P.; Hays, J. M.; Hayward, H. S.; Haywood, S. J.; Head, S. J.; Heck, T.; Hedberg, V.; Heelan, L.; Heer, S.; Heidegger, K. K.; Heim, S.; Heim, T.; Heinemann, B.; Heinrich, J. J.; Heinrich, L.; Heinz, C.; Hejbal, J.; Helary, L.; Held, A.; Hellman, S.; Helsens, C.; Henderson, R. C. W.; Heng, Y.; Henkelmann, S.; Henriques Correia, A. M.; Henrot-Versille, S.; Herbert, G. H.; Herde, H.; Herget, V.; Hernández Jiménez, Y.; Herr, H.; Herten, G.; Hertenberger, R.; Hervas, L.; Herwig, T. C.; Hesketh, G. G.; Hessey, N. P.; Hetherly, J. W.; Higashino, S.; Higón-Rodriguez, E.; Hildebrand, K.; Hill, E.; Hill, J. C.; Hiller, K. H.; Hillier, S. J.; Hils, M.; Hinchliffe, I.; Hirose, M.; Hirschbuehl, D.; Hiti, B.; Hladik, O.; Hoad, X.; Hobbs, J.; Hod, N.; Hodgkinson, M. C.; Hodgson, P.; Hoecker, A.; Hoeferkamp, M. R.; Hoenig, F.; Hohn, D.; Holmes, T. R.; Homann, M.; Honda, S.; Honda, T.; Hong, T. M.; Hooberman, B. H.; Hopkins, W. H.; Horii, Y.; Horton, A. J.; Hostachy, J.-Y.; Hou, S.; Hoummada, A.; Howarth, J.; Hoya, J.; Hrabovsky, M.; Hrdinka, J.; Hristova, I.; Hrivnac, J.; Hryn'ova, T.; Hrynevich, A.; Hsu, P. J.; Hsu, S.-C.; Hu, Q.; Hu, S.; Huang, Y.; Hubacek, Z.; Hubaut, F.; Huegging, F.; Huffman, T. B.; Hughes, E. W.; Hughes, G.; Huhtinen, M.; Huo, P.; Huseynov, N.; Huston, J.; Huth, J.; Hyneman, R.; Iacobucci, G.; Iakovidis, G.; Ibragimov, I.; Iconomidou-Fayard, L.; Idrissi, Z.; Iengo, P.; Igonkina, O.; Iizawa, T.; Ikegami, Y.; Ikeno, M.; Ilchenko, Y.; Iliadis, D.; Ilic, N.; Introzzi, G.; Ioannou, P.; Iodice, M.; Iordanidou, K.; Ippolito, V.; Isacson, M. F.; Ishijima, N.; Ishino, M.; Ishitsuka, M.; Issever, C.; Istin, S.; Ito, F.; Iturbe Ponce, J. M.; Iuppa, R.; Iwasaki, H.; Izen, J. M.; Izzo, V.; Jabbar, S.; Jackson, P.; Jacobs, R. M.; Jain, V.; Jakobi, K. B.; Jakobs, K.; Jakobsen, S.; Jakoubek, T.; Jamin, D. O.; Jana, D. K.; Jansky, R.; Janssen, J.; Janus, M.; Janus, P. A.; Jarlskog, G.; Javadov, N.; Javůrek, T.; Javurkova, M.; Jeanneau, F.; Jeanty, L.; Jejelava, J.; Jelinskas, A.; Jenni, P.; Jeske, C.; Jézéquel, S.; Ji, H.; Jia, J.; Jiang, H.; Jiang, Y.; Jiang, Z.; Jiggins, S.; Jimenez Pena, J.; Jin, S.; Jinaru, A.; Jinnouchi, O.; Jivan, H.; Johansson, P.; Johns, K. A.; Johnson, C. A.; Johnson, W. J.; Jon-And, K.; Jones, R. W. L.; Jones, S. D.; Jones, S.; Jones, T. J.; Jongmanns, J.; Jorge, P. M.; Jovicevic, J.; Ju, X.; Juste Rozas, A.; Köhler, M. K.; Kaczmarska, A.; Kado, M.; Kagan, H.; Kagan, M.; Kahn, S. J.; Kaji, T.; Kajomovitz, E.; Kalderon, C. W.; Kaluza, A.; Kama, S.; Kamenshchikov, A.; Kanaya, N.; Kanjir, L.; Kantserov, V. A.; Kanzaki, J.; Kaplan, B.; Kaplan, L. S.; Kar, D.; Karakostas, K.; Karastathis, N.; Kareem, M. J.; Karentzos, E.; Karpov, S. N.; Karpova, Z. M.; Karthik, K.; Kartvelishvili, V.; Karyukhin, A. N.; Kasahara, K.; Kashif, L.; Kass, R. D.; Kastanas, A.; Kataoka, Y.; Kato, C.; Katre, A.; Katzy, J.; Kawade, K.; Kawagoe, K.; Kawamoto, T.; Kawamura, G.; Kay, E. F.; Kazanin, V. F.; Keeler, R.; Kehoe, R.; Keller, J. S.; Kellermann, E.; Kempster, J. J.; Kendrick, J.; Keoshkerian, H.; Kepka, O.; Kerševan, B. P.; Kersten, S.; Keyes, R. A.; Khader, M.; Khalil-zada, F.; Khanov, A.; Kharlamov, A. G.; Kharlamova, T.; Khodinov, A.; Khoo, T. 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A.; Sokhrannyi, G.; Solans Sanchez, C. A.; Solar, M.; Soldatov, E. Yu.; Soldevila, U.; Solodkov, A. A.; Soloshenko, A.; Solovyanov, O. V.; Solovyev, V.; Sommer, P.; Son, H.; Sopczak, A.; Sosa, D.; Sotiropoulou, C. L.; Soualah, R.; Soukharev, A. M.; South, D.; Sowden, B. C.; Spagnolo, S.; Spalla, M.; Spangenberg, M.; Spanò, F.; Sperlich, D.; Spettel, F.; Spieker, T. M.; Spighi, R.; Spigo, G.; Spiller, L. A.; Spousta, M.; St. Denis, R. D.; Stabile, A.; Stamen, R.; Stamm, S.; Stanecka, E.; Stanek, R. W.; Stanescu, C.; Stanitzki, M. M.; Stapf, B. S.; Stapnes, S.; Starchenko, E. A.; Stark, G. H.; Stark, J.; Stark, S. H.; Staroba, P.; Starovoitov, P.; Stärz, S.; Staszewski, R.; Stegler, M.; Steinberg, P.; Stelzer, B.; Stelzer, H. J.; Stelzer-Chilton, O.; Stenzel, H.; Stewart, G. A.; Stockton, M. C.; Stoebe, M.; Stoicea, G.; Stolte, P.; Stonjek, S.; Stradling, A. R.; Straessner, A.; Stramaglia, M. E.; Strandberg, J.; Strandberg, S.; Strauss, M.; Strizenec, P.; Ströhmer, R.; Strom, D. M.; Stroynowski, R.; Strubig, A.; Stucci, S. A.; Stugu, B.; Styles, N. A.; Su, D.; Su, J.; Suchek, S.; Sugaya, Y.; Suk, M.; Sulin, V. V.; Sultan, DMS; Sultansoy, S.; Sumida, T.; Sun, S.; Sun, X.; Suruliz, K.; Suster, C. J. E.; Sutton, M. R.; Suzuki, S.; Svatos, M.; Swiatlowski, M.; Swift, S. P.; Sykora, I.; Sykora, T.; Ta, D.; Tackmann, K.; Taenzer, J.; Taffard, A.; Tafirout, R.; Tahirovic, E.; Taiblum, N.; Takai, H.; Takashima, R.; Takasugi, E. H.; Takeshita, T.; Takubo, Y.; Talby, M.; Talyshev, A. A.; Tanaka, J.; Tanaka, M.; Tanaka, R.; Tanaka, S.; Tanioka, R.; Tannenwald, B. B.; Tapia Araya, S.; Tapprogge, S.; Tarem, S.; Tartarelli, G. F.; Tas, P.; Tasevsky, M.; Tashiro, T.; Tassi, E.; Tavares Delgado, A.; Tayalati, Y.; Taylor, A. C.; Taylor, A. J.; Taylor, G. N.; Taylor, P. T. E.; Taylor, W.; Teixeira-Dias, P.; Temple, D.; Ten Kate, H.; Teng, P. K.; Teoh, J. J.; Tepel, F.; Terada, S.; Terashi, K.; Terron, J.; Terzo, S.; Testa, M.; Teuscher, R. J.; Theveneaux-Pelzer, T.; Thiele, F.; Thomas, J. P.; Thomas-Wilsker, J.; Thompson, P. D.; Thompson, A. S.; Thomsen, L. A.; Thomson, E.; Tibbetts, M. J.; Ticse Torres, R. E.; Tikhomirov, V. O.; Tikhonov, Yu. A.; Timoshenko, S.; Tipton, P.; Tisserant, S.; Todome, K.; Todorova-Nova, S.; Todt, S.; Tojo, J.; Tokár, S.; Tokushuku, K.; Tolley, E.; Tomlinson, L.; Tomoto, M.; Tompkins, L.; Toms, K.; Tong, B.; Tornambe, P.; Torrence, E.; Torres, H.; Torró Pastor, E.; Toth, J.; Touchard, F.; Tovey, D. R.; Treado, C. J.; Trefzger, T.; Tresoldi, F.; Tricoli, A.; Trigger, I. M.; Trincaz-Duvoid, S.; Tripiana, M. F.; Trischuk, W.; Trocmé, B.; Trofymov, A.; Troncon, C.; Trottier-McDonald, M.; Trovatelli, M.; Truong, L.; Trzebinski, M.; Trzupek, A.; Tsang, K. W.; Tseng, J. C.-L.; Tsiareshka, P. V.; Tsipolitis, G.; Tsirintanis, N.; Tsiskaridze, S.; Tsiskaridze, V.; Tskhadadze, E. G.; Tsui, K. M.; Tsukerman, I. I.; Tsulaia, V.; Tsuno, S.; Tsybychev, D.; Tu, Y.; Tudorache, A.; Tudorache, V.; Tulbure, T. T.; Tuna, A. N.; Tupputi, S. A.; Turchikhin, S.; Turgeman, D.; Turk Cakir, I.; Turra, R.; Tuts, P. M.; Ucchielli, G.; Ueda, I.; Ughetto, M.; Ukegawa, F.; Unal, G.; Undrus, A.; Unel, G.; Ungaro, F. C.; Unno, Y.; Unverdorben, C.; Urban, J.; Urquijo, P.; Urrejola, P.; Usai, G.; Usui, J.; Vacavant, L.; Vacek, V.; Vachon, B.; Vadla, K. O. H.; Vaidya, A.; Valderanis, C.; Valdes Santurio, E.; Valente, M.; Valentinetti, S.; Valero, A.; Valéry, L.; Valkar, S.; Vallier, A.; Valls Ferrer, J. A.; Van Den Wollenberg, W.; van der Graaf, H.; van Gemmeren, P.; Van Nieuwkoop, J.; van Vulpen, I.; van Woerden, M. C.; Vanadia, M.; Vandelli, W.; Vaniachine, A.; Vankov, P.; Vardanyan, G.; Vari, R.; Varnes, E. W.; Varni, C.; Varol, T.; Varouchas, D.; Vartapetian, A.; Varvell, K. E.; Vasquez, J. G.; Vasquez, G. A.; Vazeille, F.; Vazquez Furelos, D.; Vazquez Schroeder, T.; Veatch, J.; Veeraraghavan, V.; Veloce, L. M.; Veloso, F.; Veneziano, S.; Ventura, A.; Venturi, M.; Venturi, N.; Venturini, A.; Vercesi, V.; Verducci, M.; Verkerke, W.; Vermeulen, A. T.; Vermeulen, J. C.; Vetterli, M. C.; Viaux Maira, N.; Viazlo, O.; Vichou, I.; Vickey, T.; Vickey Boeriu, O. E.; Viehhauser, G. H. A.; Viel, S.; Vigani, L.; Villa, M.; Perez, M. Villaplana; Vilucchi, E.; Vincter, M. G.; Vinogradov, V. B.; Vishwakarma, A.; Vittori, C.; Vivarelli, I.; Vlachos, S.; Vogel, M.; Vokac, P.; Volpi, G.; von der Schmitt, H.; von Toerne, E.; Vorobel, V.; Vorobev, K.; Vos, M.; Voss, R.; Vossebeld, J. H.; Vranjes, N.; Vranjes Milosavljevic, M.; Vrba, V.; Vreeswijk, M.; Vuillermet, R.; Vukotic, I.; Wagner, P.; Wagner, W.; Wagner-Kuhr, J.; Wahlberg, H.; Wahrmund, S.; Walder, J.; Walker, R.; Walkowiak, W.; Wallangen, V.; Wang, C.; Wang, C.; Wang, F.; Wang, H.; Wang, H.; Wang, J.; Wang, J.; Wang, Q.; Wang, R.-J.; Wang, R.; Wang, S. M.; Wang, T.; Wang, W.; Wang, W.; Wang, Z.; Wanotayaroj, C.; Warburton, A.; Ward, C. P.; Wardrope, D. R.; Washbrook, A.; Watkins, P. M.; Watson, A. T.; Watson, M. F.; Watts, G.; Watts, S.; Waugh, B. M.; Webb, A. F.; Webb, S.; Weber, M. S.; Weber, S. W.; Weber, S. A.; Webster, J. S.; Weidberg, A. R.; Weinert, B.; Weingarten, J.; Weirich, M.; Weiser, C.; Weits, H.; Wells, P. S.; Wenaus, T.; Wengler, T.; Wenig, S.; Wermes, N.; Werner, M. D.; Werner, P.; Wessels, M.; Weston, T. D.; Whalen, K.; Whallon, N. L.; Wharton, A. M.; White, A. S.; White, A.; White, M. J.; White, R.; Whiteson, D.; Whitmore, B. W.; Wickens, F. J.; Wiedenmann, W.; Wielers, M.; Wiglesworth, C.; Wiik-Fuchs, L. A. M.; Wildauer, A.; Wilk, F.; Wilkens, H. G.; Williams, H. H.; Williams, S.; Willis, C.; Willocq, S.; Wilson, J. A.; Wingerter-Seez, I.; Winkels, E.; Winklmeier, F.; Winston, O. J.; Winter, B. T.; Wittgen, M.; Wobisch, M.; Wolf, T. M. H.; Wolff, R.; Wolter, M. W.; Wolters, H.; Wong, V. W. S.; Worm, S. D.; Wosiek, B. K.; Wotschack, J.; Wozniak, K. W.; Wu, M.; Wu, S. L.; Wu, X.; Wu, Y.; Wyatt, T. R.; Wynne, B. M.; Xella, S.; Xi, Z.; Xia, L.; Xu, D.; Xu, L.; Xu, T.; Yabsley, B.; Yacoob, S.; Yamaguchi, D.; Yamaguchi, Y.; Yamamoto, A.; Yamamoto, S.; Yamanaka, T.; Yamane, F.; Yamatani, M.; Yamazaki, Y.; Yan, Z.; Yang, H.; Yang, H.; Yang, Y.; Yang, Z.; Yao, W.-M.; Yap, Y. C.; Yasu, Y.; Yatsenko, E.; Yau Wong, K. H.; Ye, J.; Ye, S.; Yeletskikh, I.; Yigitbasi, E.; Yildirim, E.; Yorita, K.; Yoshihara, K.; Young, C.; Young, C. J. S.; Yu, J.; Yu, J.; Yuen, S. P. Y.; Yusuff, I.; Zabinski, B.; Zacharis, G.; Zaidan, R.; Zaitsev, A. M.; Zakharchuk, N.; Zalieckas, J.; Zaman, A.; Zambito, S.; Zanzi, D.; Zeitnitz, C.; Zemaityte, G.; Zemla, A.; Zeng, J. C.; Zeng, Q.; Zenin, O.; Ženiš, T.; Zerwas, D.; Zhang, D.; Zhang, D.; Zhang, F.; Zhang, G.; Zhang, H.; Zhang, J.; Zhang, L.; Zhang, L.; Zhang, M.; Zhang, P.; Zhang, R.; Zhang, R.; Zhang, X.; Zhang, Y.; Zhang, Z.; Zhao, X.; Zhao, Y.; Zhao, Z.; Zhemchugov, A.; Zhou, B.; Zhou, C.; Zhou, L.; Zhou, M.; Zhou, M.; Zhou, N.; Zhu, C. G.; Zhu, H.; Zhu, J.; Zhu, Y.; Zhuang, X.; Zhukov, K.; Zibell, A.; Zieminska, D.; Zimine, N. I.; Zimmermann, C.; Zimmermann, S.; Zinonos, Z.; Zinser, M.; Ziolkowski, M.; Živković, L.; Zobernig, G.; Zoccoli, A.; Zou, R.; zur Nedden, M.; Zwalinski, L.

2017-10-01

Inclusive and differential fiducial cross sections of Higgs boson production in proton-proton collisions are measured in the H → ZZ * → 4 ℓ decay channel. The proton-proton collision data were produced at the Large Hadron Collider at a centre-of-mass energy of 13 TeV and recorded by the ATLAS detector in 2015 and 2016, corresponding to an integrated luminosity of 36.1 fb-1. The inclusive fiducial cross section in the H → ZZ * → 4ℓ decay channel is measured to be 3.62 ± 0.50(stat) - 0.20 + 0.25 (sys) fb, in agreement with the Standard Model prediction of 2 .91 ± 0 .13 fb. The cross section is also extrapolated to the total phase space including all Standard Model Higgs boson decays. Several differential fiducial cross sections are measured for observables sensitive to the Higgs boson production and decay, including kinematic distributions of jets produced in association with the Higgs boson. Good agreement is found between data and Standard Model predictions. The results are used to put constraints on anomalous Higgs boson interactions with Standard Model particles, using the pseudo-observable extension to the kappa-framework. [Figure not available: see fulltext.

Digital database of channel cross-section surveys, Mount St. Helens, Washington

USGS Publications Warehouse

Mosbrucker, Adam R.; Spicer, Kurt R.; Major, Jon J.; Saunders, Dennis R.; Christianson, Tami S.; Kingsbury, Cole G.

2015-08-06

Stream-channel cross-section survey data are a fundamental component to studies of fluvial geomorphology. Such data provide important parameters required by many open-channel flow models, sediment-transport equations, sediment-budget computations, and flood-hazard assessments. At Mount St. Helens, Washington, the long-term response of channels to the May 18, 1980, eruption, which dramatically altered the hydrogeomorphic regime of several drainages, is documented by an exceptional time series of repeat stream-channel cross-section surveys. More than 300 cross sections, most established shortly following the eruption, represent more than 100 kilometers of surveyed topography. Although selected cross sections have been published previously in print form, we present a comprehensive digital database that includes geospatial and tabular data. Furthermore, survey data are referenced to a common geographic projection and to common datums. Database design, maintenance, and data dissemination are accomplished through a geographic information system (GIS) platform, which integrates survey data acquired with theodolite, total station, and global navigation satellite system (GNSS) instrumentation. Users can interactively perform advanced queries and geospatial time-series analysis. An accuracy assessment provides users the ability to quantify uncertainty within these data. At the time of publication, this project is ongoing. Regular database updates are expected; users are advised to confirm they are using the latest version.

Cross-over endocytosis of claudins is mediated by interactions via their extracellular loops.

PubMed

Gehne, Nora; Lamik, Agathe; Lehmann, Martin; Haseloff, Reiner F; Andjelkovic, Anuska V; Blasig, Ingolf E

2017-01-01

Claudins (Cldns) are transmembrane tight junction (TJ) proteins that paracellularly seal endo- and epithelial barriers by their interactions within the TJs. However, the mechanisms allowing TJ remodeling while maintaining barrier integrity are largely unknown. Cldns and occludin are heterophilically and homophilically cross-over endocytosed into neighboring cells in large, double membrane vesicles. Super-resolution microscopy confirmed the presence of Cldns in these vesicles and revealed a distinct separation of Cldns derived from opposing cells within cross-over endocytosed vesicles. Colocalization of cross-over endocytosed Cldn with the autophagosome markers as well as inhibition of autophagosome biogenesis verified involvement of the autophagosomal pathway. Accordingly, cross-over endocytosed Cldns underwent lysosomal degradation as indicated by lysosome markers. Cross-over endocytosis of Cldn5 depended on clathrin and caveolin pathways but not on dynamin. Cross-over endocytosis also depended on Cldn-Cldn-interactions. Amino acid substitutions in the second extracellular loop of Cldn5 (F147A, Q156E) caused impaired cis- and trans-interaction, as well as diminished cross-over endocytosis. Moreover, F147A exhibited an increased mobility in the membrane, while Q156E was not as mobile but enhanced the paracellular permeability. In conclusion, the endocytosis of TJ proteins depends on their ability to interact strongly with each other in cis and trans, and the mobility of Cldns in the membrane is not necessarily an indicator of barrier permeability. TJ-remodeling via cross-over endocytosis represents a general mechanism for the degradation of transmembrane proteins in cell-cell contacts and directly links junctional membrane turnover to autophagy.

Measurement of the muon neutrino inclusive charged-current cross section in the energy range of 1-3 GeV with the T2K INGRID detector

NASA Astrophysics Data System (ADS)

Abe, K.; Andreopoulos, C.; Antonova, M.; Aoki, S.; Ariga, A.; Assylbekov, S.; Autiero, D.; Barbi, M.; Barker, G. J.; Barr, G.; Bartet-Friburg, P.; Batkiewicz, M.; Bay, F.; Berardi, V.; Berkman, S.; Bhadra, S.; Blondel, A.; Bolognesi, S.; Bordoni, S.; Boyd, S. B.; Brailsford, D.; Bravar, A.; Bronner, C.; Calland, R. G.; Cao, S.; Caravaca Rodríguez, J.; Cartwright, S. L.; Castillo, R.; Catanesi, M. G.; Cervera, A.; Cherdack, D.; Chikuma, N.; Christodoulou, G.; Clifton, A.; Coleman, J.; Collazuol, G.; Cremonesi, L.; Dabrowska, A.; De Rosa, G.; Dealtry, T.; Dennis, S. R.; Densham, C.; Dewhurst, D.; Di Lodovico, F.; Di Luise, S.; Dolan, S.; Drapier, O.; Duffy, K.; Dumarchez, J.; Dytman, S.; Dziewiecki, M.; Emery-Schrenk, S.; Ereditato, A.; Feusels, T.; Finch, A. J.; Fiorentini, G. A.; Friend, M.; Fujii, Y.; Fukuda, D.; Fukuda, Y.; Furmanski, A. P.; Galymov, V.; Garcia, A.; Giffin, S.; Giganti, C.; Gilje, K.; Gonin, M.; Grant, N.; Hadley, D. R.; Haegel, L.; Haigh, M. D.; Hamilton, P.; Hansen, D.; Hara, T.; Hartz, M.; Hasegawa, T.; Hastings, N. C.; Hayashino, T.; Hayato, Y.; Helmer, R. L.; Hierholzer, M.; Hillairet, A.; Himmel, A.; Hiraki, T.; Hirota, S.; Holeczek, J.; Horikawa, S.; Hosomi, F.; Huang, K.; Ichikawa, A. K.; Ieki, K.; Ikeda, M.; Imber, J.; Insler, J.; Intonti, R. A.; Irvine, T. J.; Ishida, T.; Ishii, T.; Iwai, E.; Iwamoto, K.; Izmaylov, A.; Jacob, A.; Jamieson, B.; Jiang, M.; Johnson, S.; Jo, J. H.; Jonsson, P.; Jung, C. K.; Kabirnezhad, M.; Kaboth, A. C.; Kajita, T.; Kakuno, H.; Kameda, J.; Karlen, D.; Karpikov, I.; Katori, T.; Kearns, E.; Khabibullin, M.; Khotjantsev, A.; Kielczewska, D.; Kikawa, T.; Kim, H.; Kim, J.; King, S.; Kisiel, J.; Kobayashi, T.; Koch, L.; Koga, T.; Konaka, A.; Kondo, K.; Kopylov, A.; Kormos, L. L.; Korzenev, A.; Koshio, Y.; Kropp, W.; Kudenko, Y.; Kurjata, R.; Kutter, T.; Lagoda, J.; Lamont, I.; Larkin, E.; Laveder, M.; Lawe, M.; Lazos, M.; Lindner, T.; Liptak, Z. J.; Litchfield, R. P.; Longhin, A.; Lopez, J. P.; Ludovici, L.; Lu, X.; Magaletti, L.; Mahn, K.; Malek, M.; Manly, S.; Marino, A. D.; Marteau, J.; Martin, J. F.; Martins, P.; Martynenko, S.; Maruyama, T.; Matveev, V.; Mavrokoridis, K.; Ma, W. Y.; Mazzucato, E.; McCarthy, M.; McCauley, N.; McFarland, K. S.; McGrew, C.; Mefodiev, A.; Mezzetto, M.; Mijakowski, P.; Miller, C. A.; Minamino, A.; Mineev, O.; Mine, S.; Missert, A.; Miura, M.; Moriyama, S.; Mueller, Th. A.; Murphy, S.; Myslik, J.; Nakadaira, T.; Nakahata, M.; Nakamura, K. G.; Nakamura, K.; Nakamura, K. D.; Nakayama, S.; Nakaya, T.; Nakayoshi, K.; Nantais, C.; Nielsen, C.; Nirkko, M.; Nishikawa, K.; Nishimura, Y.; Nowak, J.; O'Keeffe, H. M.; Ohta, R.; Okumura, K.; Okusawa, T.; Oryszczak, W.; Oser, S. M.; Ovsyannikova, T.; Owen, R. A.; Oyama, Y.; Palladino, V.; Palomino, J. L.; Paolone, V.; Payne, D.; Perkin, J. D.; Petrov, Y.; Pickard, L.; Pickering, L.; Pinzon Guerra, E. S.; Pistillo, C.; Popov, B.; Posiadala-Zezula, M.; Poutissou, J.-M.; Poutissou, R.; Przewlocki, P.; Quilain, B.; Radicioni, E.; Ratoff, P. N.; Ravonel, M.; Rayner, M. A. M.; Redij, A.; Reinherz-Aronis, E.; Riccio, C.; Rojas, P.; Rondio, E.; Roth, S.; Rubbia, A.; Rychter, A.; Sacco, R.; Sakashita, K.; Sánchez, F.; Sato, F.; Scantamburlo, E.; Scholberg, K.; Schoppmann, S.; Schwehr, J. D.; Scott, M.; Seiya, Y.; Sekiguchi, T.; Sekiya, H.; Sgalaberna, D.; Shah, R.; Shaikhiev, A.; Shaker, F.; Shaw, D.; Shiozawa, M.; Shirahige, T.; Short, S.; Smy, M.; Sobczyk, J. T.; Sorel, M.; Southwell, L.; Stamoulis, P.; Steinmann, J.; Stewart, T.; Suda, Y.; Suvorov, S.; Suzuki, A.; Suzuki, K.; Suzuki, S. Y.; Suzuki, Y.; Tacik, R.; Tada, M.; Takahashi, S.; Takeda, A.; Takeuchi, Y.; Tanaka, H. K.; Tanaka, H. A.; Terhorst, D.; Terri, R.; Thompson, L. F.; Tobayama, S.; Toki, W.; Tomura, T.; Touramanis, C.; Tsukamoto, T.; Tzanov, M.; Uchida, Y.; Vacheret, A.; Vagins, M.; Vallari, Z.; Vasseur, G.; Wachala, T.; Wakamatsu, K.; Walter, C. W.; Wark, D.; Warzycha, W.; Wascko, M. O.; Weber, A.; Wendell, R.; Wilkes, R. J.; Wilking, M. J.; Wilkinson, C.; Wilson, J. R.; Wilson, R. J.; Yamada, Y.; Yamamoto, K.; Yamamoto, M.; Yanagisawa, C.; Yano, T.; Yen, S.; Yershov, N.; Yokoyama, M.; Yoo, J.; Yoshida, K.; Yuan, T.; Yu, M.; Zalewska, A.; Zalipska, J.; Zambelli, L.; Zaremba, K.; Ziembicki, M.; Zimmerman, E. D.; Zito, M.; Żmuda, J.; T2K Collaboration

2016-04-01

We report a measurement of the νμ-nucleus inclusive charged-current cross section (=σc c ) on iron using data from the INGRID detector exposed to the J-PARC neutrino beam. The detector consists of 14 modules in total, which are spread over a range of off-axis angles from 0° to 1.1°. The variation in the neutrino energy spectrum as a function of the off-axis angle, combined with event topology information, is used to calculate this cross section as a function of neutrino energy. The cross section is measured to be σc c(1.1 GeV )=1.10 ±0.15 (1 0-38 cm2/nucleon) , σc c(2.0 GeV )=2.07 ±0.27 (1 0-38 cm2/nucleon) , and σc c(3.3 GeV )=2.29 ±0.45 (1 0-38 cm2/nucleon), at energies of 1.1, 2.0, and 3.3 GeV, respectively. These results are consistent with the cross section calculated by the neutrino interaction generators currently used by T2K. More importantly, the method described here opens up a new way to determine the energy dependence of neutrino-nucleus cross sections.

A Generalized Weizsacker-Williams Method Applied to Pion Production in Proton-Proton Collisions

NASA Technical Reports Server (NTRS)

Ahern, Sean C.; Poyser, William J.; Norbury, John W.; Tripathi, R. K.

2002-01-01

A new "Generalized" Weizsacker-Williams method (GWWM) is used to calculate approximate cross sections for relativistic peripheral proton-proton collisions. Instead of a mass less photon mediator, the method allows for the mediator to have mass for short range interactions. This method generalizes the Weizsacker-Williams method (WWM) from Coulomb interactions to GWWM for strong interactions. An elastic proton-proton cross section is calculated using GWWM with experimental data for the elastic p+p interaction, where the mass p+ is now the mediator. The resulting calculated cross sections is compared to existing data for the elastic proton-proton interaction. A good approximate fit is found between the data and the calculation.

Low-energy and very-low energy total cross sections for electron collisions with N2

NASA Astrophysics Data System (ADS)

Kitajima, Masashi; Kishino, Takaya; Okumura, Takuma; Kobayashi, Naomasa; Sayama, Atsushi; Mori, Yuma; Hosaka, Kouichi; Odagiri, Takeshi; Hoshino, Masamitsu; Tanaka, Hiroshi

2017-06-01

Absolute grand total cross sections for electron scattering from N2 are obtained in the energy range from 20 eV down to 5 meV with very narrow electron energy width of 9 meV using the threshold-photoelectron source. Total cross sections obtained in the present study are compared with the previous experimentally obtained results. At the very-low energy region below 50 meV, the present total cross sections are somewhat smaller than those reported by the Aarhus group [S.V. Hoffmann et al., Rev. Sci. Instrum. 73, 4157 (2002)], which has been the only experimental work that provided the total cross sections in the very-low energy region. The energy positions of the peaks in the total cross sections due to the 2Πg shape resonance are obtained with higher accuracy, due to the improved uncertainty of the energy position in the present measurement compared to the previous works. The resonance structure in the total cross sections due to the Feshbach resonances of N2 at around 11.5 eV are also observed. Analysis of the resonant structure was carried out in order to determine the values of resonance width of Feshbach resonances of N2. Contribution to the Topical Issue: "Atomic and Molecular Data and their Applications", edited by Gordon W.F. Drake, Jung-Sik Yoon, Daiji Kato, Grzegorz Karwasz.

Do early sensory cortices integrate cross-modal information?

PubMed

Kayser, Christoph; Logothetis, Nikos K

2007-09-01

Our different senses provide complementary evidence about the environment and their interaction often aids behavioral performance or alters the quality of the sensory percept. A traditional view defers the merging of sensory information to higher association cortices, and posits that a large part of the brain can be reduced into a collection of unisensory systems that can be studied in isolation. Recent studies, however, challenge this view and suggest that cross-modal interactions can already occur in areas hitherto regarded as unisensory. We review results from functional imaging and electrophysiology exemplifying cross-modal interactions that occur early during the evoked response, and at the earliest stages of sensory cortical processing. Although anatomical studies revealed several potential origins of these cross-modal influences, there is yet no clear relation between particular functional observations and specific anatomical connections. In addition, our view on sensory integration at the neuronal level is coined by many studies on subcortical model systems of sensory integration; yet, the patterns of cross-modal interaction in cortex deviate from these model systems in several ways. Consequently, future studies on cortical sensory integration need to leave the descriptive level and need to incorporate cross-modal influences into models of the organization of sensory processing. Only then will we be able to determine whether early cross-modal interactions truly merit the label sensory integration, and how they increase a sensory system's ability to scrutinize its environment and finally aid behavior.

Constraining in-medium nucleon-nucleon interactions via nucleus-nucleus reactions

NASA Astrophysics Data System (ADS)

Sammarruca, Francesca; White, Larz

2010-11-01

The nuclear equation of state is a broadly useful tool. Besides being the main input of stellar structure calculations, it allows a direct connection to the physics of nuclei. For instance, an energy functional (such as a mass formula), together with the energy/particle in nuclear matter, can be used to predict nuclear energies and radii [1]. The single-particle properties are also a key point to link infinite nuclear matter and actual nuclei. The parameters of the single-particle potential, in particular the effective mass, enter the calculations of, for instance, in-medium effective cross sections. From the well-known Glauber reaction theory, the total nucleus-nucleus reaction cross section is expressed in terms of the nuclear transparency, which, in turn, depends on the overlap of the nuclear density distributions and the elementary nucleon-nucleon (NN) cross sections. We explore the sensitivity of the reaction calculation to medium modifications of the NN cross sections to estimate the likelihood of constraining the latter through nuclear reactions. Ultimately, we wish to incorporate isospin asymmetry in the reaction model, having in mind connections with rare isotopes. [1] F. Sammarruca, arXiv:1002.00146 [nucl-th]; International Journal of Modern Physics, in press.

Charge transfer between O6+ and atomic hydrogen

NASA Astrophysics Data System (ADS)

Wu, Y.; Stancil, P. C.; Liebermann, H. P.; Buenker, R. J.; Schultz, D. R.; Hui, Y.

2011-05-01

The charge exchange process has been found to play a dominant role in the production of X-rays and/or EUV photons observed in cometary and planetary atmospheres and from the heliosphere. Charge transfer cross sections, especially state-selective cross sections, are necessary parameters in simulations of X-ray emission. In the present work, charge transfer due to collisions of ground state O6+(1s2 1 S) with atomic hydrogen has been investigated theoretically using the quantum-mechanical molecular-orbital close-coupling method (QMOCC). The multi-reference single- and double-excitation configuration interaction approach (MRDCI) has been applied to compute the adiabatic potential and nonadiabatic couplings, and the atomic basis sets used have been optimized with the method proposed previously to obtain precise potential data. Total and state-selective cross sections are calculated for energies between 10 meV/u and 10 keV/u. The QMOCC results are compared to available experimental and theoretical data as well as to new atomic-orbital close-coupling (AOCC) and classical trajectory Monte Carlo (CTMC) calculations. A recommended set of cross sections, based on the MOCC, AOCC, and CTMC calculations, is deduced which should aid in X-ray modeling studies.

Relativistic Confinement Resonances

NASA Astrophysics Data System (ADS)

Keating, David; Manson, Steven; Deshmukh, Pranawa

2017-04-01

Photoionization of confined atoms in a C60 fullerene have been under intense investigation in the recent years, in particular the confinement induced resonances, termed confinement resonances. The effects of the C60 potential are modeled by a static spherical well, with (in atomic units) inner radius r0 = 5.8, width Δ = 1.9, and depth U0 = -0.302, which is reasonable in the energy region well above the C60 plasmons. At very high Z, relativistic interactions become important contributors to even the qualitative nature of atomic properties; this is true for confined atomic properties as well. To explore the extent of these interactions, a theoretical study of several heavy atoms has been performed using the relativistic random phase approximation (RRPA) methodology. In order to determine which features in the photoionization cross section are due to relativity, calculations using the (nonrelativistic) random phase approximation with exchange method (RPAE) are performed for comparison. The existence of the second subshell of the spin-orbit-split doublets can induce new confinement resonances in the total cross section, which is the sum of the spin-orbit-split doublets, due to the shift in the doublet's threshold. Several examples for confined high-Z atoms are presented. Work supported by DOE and NSF.

Accomplishing Transformative Research in a Challenging Fiscal Environment

NASA Astrophysics Data System (ADS)

Mitchell, E. J.; Paxton, L. J.; Bust, G.

2014-12-01

The shift in funding is forcing scientists to promise transformative research for a pittance. To accomplish this, researchers need to transform their methodology to include societal buy-in, use of commercial off-the-shelf (COTS) technology, and cross-discipline platform usage. As the cutting edge of research expands to view the system on the global scale with extremely fine resolution, fiscally reasonable budgets present a challenge to be met. Consider how do we measure a specific variable over 45-degrees of latitude in an isolated and hostile region of Earth - the total electron count over the South Pole? This work examines this transformative research using hosted payloads on buoys, balloons, and unmanned aerial vehicles (UAVs). We will show cutting edge research occurring simultaneous with education and public outreach, offering societal buy-in through interactive websites and student-built hosted payloads. These interactions provide a vision to the public and a new database to the scientists. The use of COTS technology and cross-discipline (oceanography and space) platforms keep the cost low. We will discuss a general methodology for accomplishing transformative research in a challenging fiscal environment through integration of COTS technology, assimilative and first principle models, and observing systems simulation experiments (OSSEs).

Measurement of single π 0 production by coherent neutral-current ν Fe interactions in the MINOS Near Detector

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adamson, P.; Anghel, I.; Aurisano, A.

Forward single π0 production by coherent neutral-current interactions, νA→νAπ 0, is investigated using a 2.8×10 20 protons-on-target exposure of the MINOS Near Detector. For single-shower topologies, the event distribution in production angle exhibits a clear excess above the estimated background at very forward angles for visible energy in the range 1–8 GeV. Cross sections are obtained for the detector medium comprised of 80% iron and 20% carbon nuclei withmore » $$\\langle$$A$$\\rangle$$=48, the highest-$$\\langle$$A$$\\rangle$$ target used to date in the study of this coherent reaction. In conclusion, the total cross section for coherent neutral-current single π 0 production initiated by the ν μ flux of the NuMI low-energy beam with mean (mode) E ν of 4.9 GeV (3.0 GeV), is 77.6±5.0(stat)$$+15.0\\atop{-16.8}$$(syst)×10 -40 cm 2 pernucleus. Finally, the results are in good agreement with predictions of the Berger-Sehgal model.« less

Cross-cultural differences in beliefs and practices that affect the language spoken to children: mothers with Indian and Western heritage.

PubMed

Simmons, Noreen; Johnston, Judith

2007-01-01

Speech-language pathologists often advise families about interaction patterns that will facilitate language learning. This advice is typically based on research with North American families of European heritage and may not be culturally suited for non-Western families. The goal of the project was to identify differences in the beliefs and practices of Indian and Euro-Canadian mothers that would affect patterns of talk to children. A total of 47 Indian mothers and 51 Euro-Canadian mothers of preschool age children completed a written survey concerning child-rearing practices and beliefs, especially those about talk to children. Discriminant analyses indicated clear cross-cultural differences and produced functions that could predict group membership with a 96% accuracy rate. Items contributing most to these functions concerned the importance of family, perceptions of language learning, children's use of language in family and society, and interactions surrounding text. Speech-language pathologists who wish to adapt their services for families of Indian heritage should remember the centrality of the family, the likelihood that there will be less emphasis on early independence and achievement, and the preference for direct instruction.

Cross-Sectional Study of Young Adults Diagnosed With Juvenile Fibromyalgia: Social Support and Its Impact on Functioning and Mood.

PubMed

Lynch-Jordan, Anne M; Sil, Soumitri; Bromberg, Maggie; Ting, Tracy V; Kashikar-Zuck, Susmita

2015-11-01

Juvenile-onset fibromyalgia (JFM) affects physical, social, and emotional functioning. Little is known about how social support and social interactions are impacted in the transition to young adulthood for patients diagnosed with JFM. Young adults (Mage = 21.6) diagnosed with JFM during adolescence (N = 94) and matched healthy controls (N = 33) completed measures of social network size and diversity, perceived social support, physical functioning, and depressive symptoms as part of a cross-sectional survey study. No difference in social network diversity was found, although JFM patients reported fewer total people within their social networks. JFM patients reported poorer emotional and tangible support and fewer positive social interactions than healthy controls. After controlling for condition and pain intensity, the level of perceived social support was a significant predictor of physical functioning and depressive symptoms, whereas social network size also contributed uniquely to physical functioning. Given the developmental importance of social support in adolescence and young adulthood, interventions should include methods of improving social support into fibromyalgia management. Copyright © 2015 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

Measurement of single π 0 production by coherent neutral-current ν Fe interactions in the MINOS Near Detector

DOE PAGES

Adamson, P.; Anghel, I.; Aurisano, A.; ...

2016-10-26

Forward single π0 production by coherent neutral-current interactions, νA→νAπ 0, is investigated using a 2.8×10 20 protons-on-target exposure of the MINOS Near Detector. For single-shower topologies, the event distribution in production angle exhibits a clear excess above the estimated background at very forward angles for visible energy in the range 1–8 GeV. Cross sections are obtained for the detector medium comprised of 80% iron and 20% carbon nuclei withmore » $$\\langle$$A$$\\rangle$$=48, the highest-$$\\langle$$A$$\\rangle$$ target used to date in the study of this coherent reaction. In conclusion, the total cross section for coherent neutral-current single π 0 production initiated by the ν μ flux of the NuMI low-energy beam with mean (mode) E ν of 4.9 GeV (3.0 GeV), is 77.6±5.0(stat)$$+15.0\\atop{-16.8}$$(syst)×10 -40 cm 2 pernucleus. Finally, the results are in good agreement with predictions of the Berger-Sehgal model.« less

Interaction between drug and placebo effects: a cross-over balanced placebo design trial.

PubMed

Hammami, Muhammad M; Al-Gaai, Eman A; Alvi, Syed; Hammami, Muhammad B

2010-11-19

The total effect of a medication is the sum of its drug effect, placebo effect (meaning response), and their possible interaction. Current interpretation of clinical trials' results assumes no interaction. Demonstrating such an interaction has been difficult due to lack of an appropriate study design. 180 adults were randomized to caffeine (300 mg) or placebo groups. Each group received the assigned intervention described by the investigators as caffeine or placebo, in a randomized crossover design. 4-hour-area-under-the-curve of energy, sleepiness, nausea (on 100 mm visual analog scales), and systolic blood pressure levels as well as caffeine pharmacokinetics (in 22 volunteers nested in the caffeine group) were determined. Caffeine drug, placebo, placebo-plus-interaction, and total effects were estimated by comparing outcomes after, receiving caffeine described as placebo to receiving placebo described as placebo, receiving placebo described as caffeine or placebo, receiving caffeine described as caffeine or placebo, and receiving caffeine described as caffeine to receiving placebo described as placebo, respectively. The placebo effect on area-under-the-curve of energy (mean difference) and sleepiness (geometric mean ratio) was larger than placebo-plus-interaction effect (16.6 [95% CI, 4.1 to 29.0] vs. 8.4 [-4.2 to 21.0] mm*hr and 0.58 [0.39 to 0.86] vs. 0.69 [0.49 to 0.97], respectively), similar in size to drug effect (20.8 [3.8 to 37.8] mm*hr and 0.49 [0.30 to 0.91], respectively), and its combination with the later was larger than total caffeine effect (29.5 [11.9 to 47.1] mm*hr and 0.37 [0.22 to 0.64]). Placebo-plus-interaction effect increased caffeine terminal half-life by 0.40 [0.12 to 0.68] hr (P=0.007). Drug and placebo effects of a medication may be less than additive, which influences the interpretation of clinical trials. The placebo effect may increase active drug terminal half-life, a novel mechanism of placebo action. ClinicalTrials.gov identification number - NCT00426010.

Trust and Influence

DTIC Science & Technology

2012-03-05

DISTRIBUTION A: Approved for public release; distribution is unlimited. Program Trends •Trust in Autonomous Systems • Cross - cultural Trust...Trust & trustworthiness are independent (Mayer et al, 1995) •Trust is relational •Humans in cross - cultural interactions •Complex human-machine...Interpersonal Trustworthiness •Ability •Benevolence •Integrity Trust Metrics Cross - Cultural Trust Issues Human-Machine Interactions Autonomous

Using virtual reality to train children in safe street-crossing skills.

PubMed

Schwebel, David C; McClure, Leslie A

2010-02-01

Pedestrian injuries are among the leading causes of morbidity and mortality in middle childhood. One limitation to existing pedestrian safety interventions is that they do not provide children with repeated practice needed to develop the complex perceptual and cognitive skills required for safe street crossing. Virtual reality offers training through repeated unsupervised practice without risk, automated feedback on success of crossings, adjustment of traffic to match children's skill and a fun, appealing environment for training. To test the efficacy of virtual reality to train child pedestrians in safe street crossing. Birmingham, Alabama, USA. A randomised controlled trial is underway with an expected sample of four groups of 60 children aged 7-8 years (total N=240). One group receives training in an interactive, immersive virtual pedestrian environment. A second receives pedestrian safety training via widely used video and computer strategies. The third group receives what is judged to be the most efficacious treatment currently available, individualised behavioural training at streetside locations. The fourth group serves as a no-contact control group. All participants are exposed to a range of field and laboratory-based measures of pedestrian skill during baseline and post-intervention visits, as well as during a 6-month follow-up assessment. Primary analyses will be conducted through linear mixed models testing change over time in the four intervention groups. Three pedestrian safety measures will serve as primary outcomes: temporal gap before initiating crossing, temporal gap remaining after crossing and attention to traffic while waiting to cross.

Kernel reconstruction methods for Doppler broadening - Temperature interpolation by linear combination of reference cross sections at optimally chosen temperatures

NASA Astrophysics Data System (ADS)

Ducru, Pablo; Josey, Colin; Dibert, Karia; Sobes, Vladimir; Forget, Benoit; Smith, Kord

2017-04-01

This article establishes a new family of methods to perform temperature interpolation of nuclear interactions cross sections, reaction rates, or cross sections times the energy. One of these quantities at temperature T is approximated as a linear combination of quantities at reference temperatures (Tj). The problem is formalized in a cross section independent fashion by considering the kernels of the different operators that convert cross section related quantities from a temperature T0 to a higher temperature T - namely the Doppler broadening operation. Doppler broadening interpolation of nuclear cross sections is thus here performed by reconstructing the kernel of the operation at a given temperature T by means of linear combination of kernels at reference temperatures (Tj). The choice of the L2 metric yields optimal linear interpolation coefficients in the form of the solutions of a linear algebraic system inversion. The optimization of the choice of reference temperatures (Tj) is then undertaken so as to best reconstruct, in the L∞ sense, the kernels over a given temperature range [Tmin ,Tmax ]. The performance of these kernel reconstruction methods is then assessed in light of previous temperature interpolation methods by testing them upon isotope 238U. Temperature-optimized free Doppler kernel reconstruction significantly outperforms all previous interpolation-based methods, achieving 0.1% relative error on temperature interpolation of 238U total cross section over the temperature range [ 300 K , 3000 K ] with only 9 reference temperatures.

Calculation of total electron excitation cross-sections and partial electron ionization cross-sections for the elements. Ph.D. Thesis

NASA Technical Reports Server (NTRS)

Green, T. J.

1973-01-01

Computer programs were used to calculate the total electron excitation cross-section for atoms and the partial ionization cross-section. The approximations to the scattering amplitude used are as follows: (1) Born, Bethe, and Modified Bethe for non-exchange excitation; (2) Ochkur for exchange excitation; and (3) Coulomb-Born of non-exchange ionization. The amplitudes are related to the differential cross-sections which are integrated to give the total excitation (or partial ionization) cross-section for the collision. The atomic wave functions used are Hartree-Fock-Slater functions for bound states and the coulomb wave function for the continuum. The programs are presented and the results are examined.

Nucleon-Nucleon Total Cross Section

NASA Technical Reports Server (NTRS)

Norbury, John W.

2008-01-01

The total proton-proton and neutron-proton cross sections currently used in the transport code HZETRN show significant disagreement with experiment in the GeV and EeV energy ranges. The GeV range is near the region of maximum cosmic ray intensity. It is therefore important to correct these cross sections, so that predictions of space radiation environments will be accurate. Parameterizations of nucleon-nucleon total cross sections are developed which are accurate over the entire energy range of the cosmic ray spectrum.

Cross-linking measurements of the Potato leafroll virus reveal protein interaction topologies required for virion stability, aphid transmission, and virus-plant interactions.

PubMed

Chavez, Juan D; Cilia, Michelle; Weisbrod, Chad R; Ju, Ho-Jong; Eng, Jimmy K; Gray, Stewart M; Bruce, James E

2012-05-04

Protein interactions are critical determinants of insect transmission for viruses in the family Luteoviridae. Two luteovirid structural proteins, the capsid protein (CP) and the readthrough protein (RTP), contain multiple functional domains that regulate virus transmission. There is no structural information available for these economically important viruses. We used Protein Interaction Reporter (PIR) technology, a strategy that uses chemical cross-linking and high resolution mass spectrometry, to discover topological features of the Potato leafroll virus (PLRV) CP and RTP that are required for the diverse biological functions of PLRV virions. Four cross-linked sites were repeatedly detected, one linking CP monomers, two within the RTP, and one linking the RTP and CP. Virus mutants with triple amino acid deletions immediately adjacent to or encompassing the cross-linked sites were defective in virion stability, RTP incorporation into the capsid, and aphid transmission. Plants infected with a new, infectious PLRV mutant lacking 26 amino acids encompassing a cross-linked site in the RTP exhibited a delay in the appearance of systemic infection symptoms. PIR technology provided the first structural insights into luteoviruses which are crucially lacking and are involved in vector-virus and plant-virus interactions. These are the first cross-linking measurements on any infectious, insect-transmitted virus.

Cross-linking measurements of the Potato leafroll virus reveal protein interaction topologies required for virion stability, aphid transmission, and virus-plant interactions

PubMed Central

Chavez, Juan D.; Cilia, Michelle; Weisbrod, Chad R.; Ju, Ho-Jong; Eng, Jimmy K.; Gray, Stewart M.; Bruce, James E.

2012-01-01

Protein interactions are critical determinants of insect-transmission for viruses in the family Luteoviridae. Two luteovirid structural proteins, the capsid protein (CP) and the readthrough protein (RTP), contain multiple functional domains that regulate virus transmission. There is no structural information available for these economically important viruses. We used Protein Interaction Reporter (PIR) technology, a strategy that uses chemical cross-linking and high resolution mass spectrometry, to discover topological features of the Potato leafroll virus (PLRV) CP and RTP that are required for the diverse biological functions of PLRV virions. Four cross-linked sites were repeatedly detected, one linking CP monomers, two within the RTP, and one linking the RTP and CP. Virus mutants with triple amino acid deletions immediately adjacent to or encompassing the cross-linked sites were defective in virion stability, RTP incorporation into the capsid, and aphid transmission. Plants infected with a new, infectious PLRV mutant lacking 26 amino acids encompassing a cross-linked site in the RTP exhibited a delay in the appearance of systemic infection symptoms. PIR technology provided the first structural insights into luteoviruses which are crucially lacking and that are involved in vector-virus and plant-virus interactions. These are the first cross-linking measurements on any infectious, insect-transmitted virus. PMID:22390342

Andreev spectrum with high spin-orbit interactions: Revealing spin splitting and topologically protected crossings

NASA Astrophysics Data System (ADS)

Murani, A.; Chepelianskii, A.; Guéron, S.; Bouchiat, H.

2017-10-01

In order to point out experimentally accessible signatures of spin-orbit interaction, we investigate numerically the Andreev spectrum of a multichannel mesoscopic quantum wire (N) with high spin-orbit interaction coupled to superconducting electrodes (S), contrasting topological and nontopological behaviors. In the nontopological case (square lattice with Rashba interactions), we find that the Kramers degeneracy of Andreev levels is lifted by a phase difference between the S reservoirs except at multiples of π , when the normal quantum wires can host several conduction channels. The level crossings at these points invariant by time-reversal symmetry are not lifted by disorder. Whereas the dc Josephson current is insensitive to these level crossings, the high-frequency admittance (susceptibility) at finite temperature reveals these level crossings and the lifting of their degeneracy at π by a small Zeeman field. We have also investigated the hexagonal lattice with intrinsic spin-orbit interaction in the range of parameters where it is a two-dimensional topological insulator with one-dimensional helical edges protected against disorder. Nontopological superconducting contacts can induce topological superconductivity in this system characterized by zero-energy level crossing of Andreev levels. Both Josephson current and finite-frequency admittance carry then very specific signatures at low temperature of this disorder-protected Andreev level crossing at π and zero energy.

Solving the scalability issue in quantum-based refinement: Q|R#1.

PubMed

Zheng, Min; Moriarty, Nigel W; Xu, Yanting; Reimers, Jeffrey R; Afonine, Pavel V; Waller, Mark P

2017-12-01

Accurately refining biomacromolecules using a quantum-chemical method is challenging because the cost of a quantum-chemical calculation scales approximately as n m , where n is the number of atoms and m (≥3) is based on the quantum method of choice. This fundamental problem means that quantum-chemical calculations become intractable when the size of the system requires more computational resources than are available. In the development of the software package called Q|R, this issue is referred to as Q|R#1. A divide-and-conquer approach has been developed that fragments the atomic model into small manageable pieces in order to solve Q|R#1. Firstly, the atomic model of a crystal structure is analyzed to detect noncovalent interactions between residues, and the results of the analysis are represented as an interaction graph. Secondly, a graph-clustering algorithm is used to partition the interaction graph into a set of clusters in such a way as to minimize disruption to the noncovalent interaction network. Thirdly, the environment surrounding each individual cluster is analyzed and any residue that is interacting with a particular cluster is assigned to the buffer region of that particular cluster. A fragment is defined as a cluster plus its buffer region. The gradients for all atoms from each of the fragments are computed, and only the gradients from each cluster are combined to create the total gradients. A quantum-based refinement is carried out using the total gradients as chemical restraints. In order to validate this interaction graph-based fragmentation approach in Q|R, the entire atomic model of an amyloid cross-β spine crystal structure (PDB entry 2oNA) was refined.

Organizational justice and major depressive episodes in Japanese employees: a cross-sectional study.

PubMed

Inoue, Akiomi; Kawakami, Norito; Tsuno, Kanami; Tomioka, Kimiko; Nakanishi, Mayuko

2013-01-01

Several European studies showed that low organizational justice (i.e., procedural justice and interactional justice) was associated with major depressive disorders. In these studies, however, the diagnosis of major depressive disorders may be underestimated because they identified only individuals who visited a doctor and received a diagnosis. Moreover, these studies did not consider neurotic personality traits, which can affect the occurrence of major depressive disorders. The purpose of the present study was to investigate the cross-sectional association of organizational justice with major depressive episodes in the past 12 months more precisely in Japanese employees. A total of 425 males and 708 females from five branches of a manufacturing company in Japan completed self-administered questionnaires measuring organizational justice, other job stressors (i.e., job strain, social support at work, and effort-reward imbalance), neuroticism, and demographic characteristics. A web-based self-administered version of the computerized Composite International Diagnostic Interview Version 3.0 (CIDI 3.0) was used to assess major depressive episodes. Logistic regression analyses were conducted. In the univariate analysis, low procedural justice and low interactional justice were significantly associated with major depressive episodes in the past 12 months. After adjusting for other job stressors and demographic characteristics, only the association of interactional justice remained significant. The moderating effect of neuroticism on the association of organizational justice with major depressive episodes in the past 12 months was not significant. Low interactional justice may be associated with major depressive disorders regardless or other job stressors or neurotic personality traits.

Tyrosine Templating in the Self-Assembly and Crystallization of Silk Fibroin.

PubMed

Partlow, Benjamin P; Bagheri, Mehran; Harden, James L; Kaplan, David L

2016-11-14

Native silk fibers exhibit strength and toughness that rival those of the best synthetic fibers. Despite significant research, further insight is still needed to understand the mechanisms by which silkworms are capable of spinning such tough fibers. Here we propose that π-π and π-OH group interactions of tyrosine side chains provide templating effects, such that the crystal-forming domains are in registration, thereby fostering the self-assembly of the spinning dope. Intrinsic fluorescence measurements, in conjunction with circular dichroism, showed that during self-assembly of regenerated silk solutions, the tyrosine residues were localized in a more hydrophobic local environment, suggesting preferential assembly. In situ Fourier transform infrared spectroscopy indicated that cross-linking of the tyrosine residues resulted in the development of extended β-sheet structure. Additionally, control of cross-link density directly influenced the degree of crystallinity upon drying. Molecular dynamics simulations were performed on silk mimetic peptides in order to more thoroughly understand the role of tyrosines. The results indicated that tyrosine residues tended to transiently colocate in solution due to π-π interactions and hydrogen bonds with adjacent residues and with the peptide backbone. These more stable tyrosine interactions resulted in reduced lateral chain fluctuations and increased incidence of coordinated intrachain association, while introduction of a dityrosine bond directly promoted the formation of β-sheet structures. In total, the experimental and modeling data support a critical role for tyrosine-tyrosine interactions as a key early feature in the self-assembly of regenerated silk protein chains and therefore are important in the robust and unusual mechanical properties ultimately achieved in the process.

Testing charged current quasi-elastic and multinucleon interaction models in the NEUT neutrino interaction generator with published datasets from the MiniBooNE and MINERνA experiments

NASA Astrophysics Data System (ADS)

Wilkinson, C.; Terri, R.; Andreopoulos, C.; Bercellie, A.; Bronner, C.; Cartwright, S.; de Perio, P.; Dobson, J.; Duffy, K.; Furmanski, A. P.; Haegel, L.; Hayato, Y.; Kaboth, A.; Mahn, K.; McFarland, K. S.; Nowak, J.; Redij, A.; Rodrigues, P.; Sánchez, F.; Schwehr, J. D.; Sinclair, P.; Sobczyk, J. T.; Stamoulis, P.; Stowell, P.; Tacik, R.; Thompson, L.; Tobayama, S.; Wascko, M. O.; Żmuda, J.

2016-04-01

There has been a great deal of theoretical work on sophisticated charged current quasi-elastic (CCQE) neutrino interaction models in recent years, prompted by a number of experimental results that measured unexpectedly large CCQE cross sections on nuclear targets. As the dominant interaction mode at T2K energies, and the signal process in oscillation analyses, it is important for the T2K experiment to include realistic CCQE cross section uncertainties in T2K analyses. To this end, T2K's Neutrino Interaction Working Group has implemented a number of recent models in NEUT, T2K's primary neutrino interaction event generator. In this paper, we give an overview of the models implemented and present fits to published νμ and ν¯ μ CCQE cross section measurements from the MiniBooNE and MINER ν A experiments. The results of the fits are used to select a default cross section model for future T2K analyses and to constrain the cross section uncertainties of the model. We find strong tension between datasets for all models investigated. Among the evaluated models, the combination of a modified relativistic Fermi gas with multinucleon CCQE-like interactions gives the most consistent description of the available data.

Production cross sections of cosmic antiprotons in the light of new data from the NA61 and LHCb experiments

NASA Astrophysics Data System (ADS)

Korsmeier, Michael; Donato, Fiorenza; Di Mauro, Mattia

2018-05-01

The cosmic-ray flux of antiprotons is measured with high precision by the space-borne particle spectrometers AMS-02. Its interpretation requires a correct description of the dominant production process for antiprotons in our Galaxy, namely, the interaction of cosmic-ray proton and helium with the interstellar medium. In light of new cross section measurements by the NA61 experiment of p +p →p ¯+X and the first ever measurement of p +He →p ¯+X by the LHCb experiment, we update the parametrization of proton-proton and proton-nucleon cross sections. We find that the LHCb p He data constrain a shape for the cross section at high energies and show for the first time how well the rescaling from the p p channel applies to a helium target. By using p p , p He and p C data we estimate the uncertainty on the Lorentz invariant cross section for p +He →p ¯+X . We use these new cross sections to compute the source term for all the production channels, considering also nuclei heavier than He both in cosmic rays and the interstellar medium. The uncertainties on the total source term are up to ±20 % and slightly increase below antiproton energies of 5 GeV. This uncertainty is dominated by the p +p →p ¯+X cross section, which translates into all channels since we derive them using the p p cross sections. The cross sections to calculate the source spectra from all relevant cosmic-ray isotopes are provided in Supplemental Material. We finally quantify the necessity of new data on antiproton production cross sections, and pin down the kinematic parameter space which should be covered by future data.

Ab initio intermolecular potential energy surface for the CO2—N2 system and related thermophysical properties

NASA Astrophysics Data System (ADS)

Crusius, Johann-Philipp; Hellmann, Robert; Castro-Palacio, Juan Carlos; Vesovic, Velisa

2018-06-01

A four-dimensional potential energy surface (PES) for the interaction between a rigid carbon dioxide molecule and a rigid nitrogen molecule was constructed based on quantum-chemical ab initio calculations up to the coupled-cluster level with single, double, and perturbative triple excitations. Interaction energies for a total of 1893 points on the PES were calculated using the counterpoise-corrected supermolecular approach and basis sets of up to quintuple-zeta quality with bond functions. The interaction energies were extrapolated to the complete basis set limit, and an analytical site-site potential function with seven sites for carbon dioxide and five sites for nitrogen was fitted to the interaction energies. The CO2—N2 cross second virial coefficient as well as the dilute gas shear viscosity, thermal conductivity, and binary diffusion coefficient of CO2—N2 mixtures were calculated for temperatures up to 2000 K to validate the PES and to provide reliable reference values for these important properties. The calculated values are in very good agreement with the best experimental data.

Sex and race/ethnic disparities in the cross-sectional association between depressive symptoms and muscle mass: the Multi-ethnic Study of Atherosclerosis.

PubMed

Remigio-Baker, Rosemay A; Allison, Matthew A; Schreiner, Pamela J; Carnethon, Mercedes R; Nettleton, Jennifer A; Mujahid, Mahasin S; Szklo, Moyses; Crum, Rosa M; Leuotsakos, Jeannie-Marie; Franco, Manuel; Jensky, Nicole; Golden, Sherita Hill

2015-09-18

The cross-sectional area of total muscle mass has been reported to decrease by about 40% for those 20-60 years of age. Depressive symptoms may discourage motivation to engage in physical activity such as strength training shown to negate muscle loss. Inflammation related to depressive symptoms may also contribute to muscle atrophy. Physiological differences by sex and race/ethnicity may also modify the association between depression and muscle mass. Evidence on the relationship between depression (or depressive symptoms) and adiposity has been mounting; however, little is known about the depressive symptoms-muscle mass association. We sought to determine the association between elevated depressive symptoms (EDS) and lean muscle mass and whether this varies by sex and race/ethnicity. Evaluating 1605 adults (45-84 years of age) from the Multi-ethnic Study of Atherosclerosis Abdominal Body Composition, Inflammation and Cardiovascular Disease Study, we examined the cross-sectional association between EDS (Center for Epidemiologic Studies for Depression Scale score≥16 and/or antidepressant use) and computed tomography-measured abdominal lean muscle mass using linear regression. Muscles were evaluated as a whole and by functionality (locomotion vs. stabilization/posture). Covariates included height, body mass index, sociodemographics, comorbidities, inflammatory markers and health behaviors (pack-years of smoking, alcohol locomotion compared to men, total intentional exercise, daily caloric intake). Sex and race/ethnicity were assessed as potential modifiers. Statistical significance was at a p<0.05 for main effects and <0.20 for interaction. Men with elevated depressive symptoms had 5.9 cm2 lower lean muscle mass for locomotion compared to men without EDS, fully-adjusted (CI=-10.5, -1.4, p=0.011). This was statistically significantly different from the null finding among women (interaction p=0.05). Chinese participants with EDS had 10.2 cm2 lower abdominal lean muscle mass for locomotion compared to those without EDS (fully-adjusted, CI=-18.3, -2.1, p=0.014), which was significantly different from the null relationship among White participants (interaction p=0.04). No association was observed between elevated depressive symptoms and muscle for stabilization/posture evaluating the whole population or stratified by sex or race/ethnicity. In the presence of elevated depressive symptoms, men and Chinese participants may have lower muscle mass, particularly for locomotion.

Exposure to polychlorinated biphenyls and the thyroid gland – examining and discussing possible longitudinal health effects in humans

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gaum, Petra M., E-mail: pgaum@ukaachen.de; Lang, Jessica; Esser, André

Background: Many previous studies have dealt with the effect of polychlorinated biphenyls (PCBs) on the thyroid gland, but their findings are inconsistent. One problem of these studies has been their use of cross-sectional designs. Objectives: The aim of the current study is to investigate longitudinal effects of PCBs on the thyroid gland, focusing on: morphological changes in thyroid tissue (i.e. thyroid volume), changes in thyroid hormones and in thyroid antibodies. Methods: A total of 122 individuals (M{sub age}=44.7) were examined over a period of four years (t{sup 1} until t{sup 4}). Medical history was collected via interviews, an ultrasound examinationmore » was performed and blood samples were taken to determine plasma PCB levels, thyroid stimulating hormone (TSH), free triiodthyronine (fT3), free thyroxine (fT4), thyroid peroxidase antibodies (TPOab), thyreoglobulin antibodies (TGab) and thyroid-stimulating hormone receptor antibodies (TSHRab). Rank correlation coefficients and mixed effect models were performed controlling for age and total lipids. Results: There were negative correlations between higher chlorinated biphenyls and fT3, cross-sectionally as well as longitudinally. We also found an interaction effect of higher-chlorinated PCBs over time for fT4 as well as TSHRab. In case of high exposure, a decrease in fT4 and an increase in TSHRab level were found over time. In regards to the other variables, our findings yielded no clear results in the examined time period. Conclusion: This is the first study to shows a PCB-related effect on fT3, fT4 and TSHRab over a four year period. The data also suggest that morphological and antibody findings remain inconsistent and do not allow for unambiguous interpretation. - Highlights: • This is a longitudinal study which includes data from four cross sections. • Higher-chlorinated biphenyls are negatively correlated with fT3. • There are interactions of time and higher-chlorinated biphenyls to TSHRab and fT4. • There is an interaction of time and dioxin-like polychlorinated biphenyls to fT4. • No consistent effects were found for thyroid volume, TSH, TPOab and TGab.« less

Inclusive particle production in e/sup +/e- interactions at 3. 8 and 4. 8 GeV. Technical report No. 77-040. [Cross sections, Feynman and Bjorken scaling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Atwood, T.L.

1976-01-01

This dissertation describes an experiment which measured the inclusive momentum spectra for hadrons and muons produced in e/sup +/e/sup -/ interactions at total center of mass energies of 3.8 and 4.8 GeV. The experiment was performed at the SPEAR electron-positron storage ring at the Stanford Linear Accelerator Center. It consisted of a single-arm spectrometer, with additional apparatus to measure charged multiplicities and to tag collinear muon and electron pairs. The Lorentz-invariant cross section for hadrons is found to exhibit Feynman scaling at all measured momenta. The invariant cross sections for pions, kaons and protons fell along the same exponential energymore » curve, exhibiting a characteristic hadron temperature of kT = 0.19 GeV. Bjorken scaling was found to hold separately for pions and for kaons for x = 2E/..sqrt..s > 0.4; however, the x-dependence of the two cross sections are significantly different. Results are also presented for the inclusive momentum distributions of the hadron charged multiplicity. An examination of inclusive muon production found the presence of a small anomalous muon signal for two-prong events noncoplanar by more than 20/sup 0/ and with p/sub ..mu../ > 1.05 GeV/c; dsigma/domega/sub 90/sup 0// = 17/sup +12//sub -9/ pb/sr. Known processes accounted for the observed muon events having charged multiplicity greater than 2, giving an upper limit at the 95% confidence level of dsigma/domega/sub 90/sup 0// < 7.5 pb/sr for any new process.« less

Track structure simulations at relativistic energies: an update on cross section calculations

NASA Astrophysics Data System (ADS)

Dingfelder, Michael

Charged particle track structure simulations follow the primary, as well as all (produced) sec-ondary particles in an event-by-event matter, from starting or ejection energies down to total stopping. They provide detailed information on the spacial distributions of energy depositions, interaction types, and radical species produced. These quantities provide a starting point to describe the interaction of the radiation with matter of biological interest and to explore and estimate the effects of radiation quality on various biological responses of these systems. Of special interest is liquid water which serves as surrogate for soft tissue. Ionization and excitation cross sections for bare charged particles can be calculated within the framework of the (relativistic) plane-wave Born approximation or the (relativistic) Bethe approximation. Both theories rely on a realistic model of the dielectric response function of the material under consideration and need to address relativistic medium polarization effects like the Fermi-density effect in a consistent way. In this talk we will review and present new and updated aspects of charged particle cross section calculations for relativistic heavy ions with liquid water and other materials of biological interest. This includes an updated model for the dielectric response function of liquid water to better reflect new data from inelastic X-ray scattering (IXS) experiments using synchrotron radiation and a model for the dielectric response function of calcium, which serves as a bone surrogate. We will also discuss the implementation of relativistic effect, especially of the Fermi-density effect into the cross section calculations. This work is supported by the National Aeronautics and Space Administration (NASA), grant no. NNJ04HF39G.

Nitric oxide and superoxide transport in a cross section of the rat outer medulla. II. Reciprocal interactions and tubulovascular cross talk.

PubMed

Edwards, Aurélie; Layton, Anita T

2010-09-01

In a companion study (Edwards A and Layton AT. Am J Physiol Renal Physiol. doi:10.1152/ajprenal.00680.2009), we developed a mathematical model of nitric oxide (NO), superoxide (O(2)(-)), and total peroxynitrite (ONOO) transport in mid-outer stripe and mid-inner stripe cross sections of the rat outer medulla (OM). We examined how the three-dimensional architecture of the rat OM, together with low medullary oxygen tension (Po(2)), affects the distribution of NO, O(2)(-), and ONOO in the rat OM. In the current study, we sought to determine generation rate and permeability values that are compatible with measurements of medullary NO concentrations and to assess the importance of tubulovascular cross talk and NO-O(2)(-) interactions under physiological conditions. Our results suggest that the main determinants of NO concentrations in the rat OM are the rate of vascular and tubular NO synthesis under hypoxic conditions, and the red blood cell (RBC) permeability to NO (P(NO)(RBC)). The lower the P(NO)(RBC), the lower the amount of NO that is scavenged by hemoglobin species, and the higher the extra-erythrocyte NO concentrations. In addition, our results indicate that basal endothelial NO production acts to significantly limit NaCl reabsorption across medullary thick ascending limbs and to sustain medullary perfusion, whereas basal epithelial NO production has a smaller impact on NaCl transport and a negligible effect on vascular tone. Our model also predicts that O(2)(-) consumption by NO significantly reduces medullary O(2)(-) concentrations, but that O(2)(-) , when present at subnanomolar concentrations, has a small impact on medullary NO bioavailability.

Final state interactions in single- and multiparticle inclusive cross sections for hadronic collisions

NASA Astrophysics Data System (ADS)

Mitov, Alexander; Sterman, George

2012-12-01

We study the role of low momentum transfer (soft) interactions between high transverse momentum heavy particles and beam remnants (spectators) in hadronic collisions. Such final state interactions are power suppressed for single-particle inclusive cross sections whenever that particle is accompanied by a recoiling high-pT partner whose momentum is not fixed. An example is the single-top inclusive cross section in top-pair production. Final state soft interactions in multiparticle inclusive cross sections, including transverse momentum distributions, however, produce leading-power corrections in the absence of hard recoiling radiation. Nonperturbative corrections due to scattering from spectators are generically suppressed by powers of Λ/pT', where Λ is a hadronic scale and pT' is the largest transverse momentum of radiation recoiling against the particles whose momenta are observed.

Cross scale interactions, nonlinearities, and forecasting catastrophic events

USGS Publications Warehouse

Peters, Debra P.C.; Pielke, Roger A.; Bestelmeyer, Brandon T.; Allen, Craig D.; Munson-McGee, Stuart; Havstad, Kris M.

2004-01-01

Catastrophic events share characteristic nonlinear behaviors that are often generated by cross-scale interactions and feedbacks among system elements. These events result in surprises that cannot easily be predicted based on information obtained at a single scale. Progress on catastrophic events has focused on one of the following two areas: nonlinear dynamics through time without an explicit consideration of spatial connectivity [Holling, C. S. (1992) Ecol. Monogr. 62, 447–502] or spatial connectivity and the spread of contagious processes without a consideration of cross-scale interactions and feedbacks [Zeng, N., Neeling, J. D., Lau, L. M. & Tucker, C. J. (1999) Science 286, 1537–1540]. These approaches rarely have ventured beyond traditional disciplinary boundaries. We provide an interdisciplinary, conceptual, and general mathematical framework for understanding and forecasting nonlinear dynamics through time and across space. We illustrate the generality and usefulness of our approach by using new data and recasting published data from ecology (wildfires and desertification), epidemiology (infectious diseases), and engineering (structural failures). We show that decisions that minimize the likelihood of catastrophic events must be based on cross-scale interactions, and such decisions will often be counterintuitive. Given the continuing challenges associated with global change, approaches that cross disciplinary boundaries to include interactions and feedbacks at multiple scales are needed to increase our ability to predict catastrophic events and develop strategies for minimizing their occurrence and impacts. Our framework is an important step in developing predictive tools and designing experiments to examine cross-scale interactions.

Neural Correlates of Cross-Cultural Adaptation: How to Improve the Training and Selection for Military Personnel Involved in Cross-Cultural Interactions

DTIC Science & Technology

2015-09-01

of this study was to better understand the culture-general skills and traits needed to conduct successful cross-cultural interactions when lacking...5  2  Study 1: Online Behavioral Study ...12  3  Study 2: Functional Neuroimaging Study .......................................................... 13  3.1

Combined effects of interaction between physical activity and nutrition on bone health in children and adolescents: a systematic review.

PubMed

Julián-Almárcegui, C; Gómez-Cabello, A; Huybrechts, I; González-Agüero, A; Kaufman, J M; Casajús, J A; Vicente-Rodríguez, G

2015-03-01

Osteoporosis is a major public health concern worldwide. Understanding the roles of diet and physical activity in ensuring adequate bone mass accrual during childhood and adolescence may help identify strategies to reduce the risk of osteoporotic fractures later in life. The present systematic review was conducted to provide an overview of the current knowledge of the combined effects of physical activity and diet on bone mass accrual in children and adolescents. Data were obtained via searches of the PubMed, EMBASE, SPORTDiscus, and ISI Web of Science databases. Studies published in English and Spanish between 1887 and August 2013 were eligible for inclusion. Two investigators evaluated the studies against the inclusion and exclusion criteria. A total of 14 studies (7 cross-sectional and 7 experimental) were included in the review. The Pedro score and the Black and Down's checklist were used to evaluate the methodological quality of the experimental and the cross-sectional studies, respectively. Study characteristics were summarized in accordance with the review's PICO criteria. Significant exercise-by-calcium interaction was detected at several different bone sites. Although the results of cross-sectional studies were inconsistent, the results of randomized controlled trials showed that exercise has the potential to improve bone health under conditions of adequate calcium intake. © The Author(s) 2015. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Cluster bulleticity

NASA Astrophysics Data System (ADS)

Massey, Richard; Kitching, Thomas; Nagai, Daisuke

2011-05-01

The unique properties of dark matter are revealed during collisions between clusters of galaxies, such as the bullet cluster (1E 0657-56) and baby bullet (MACS J0025-12). These systems provide evidence for an additional, invisible mass in the separation between the distributions of their total mass, measured via gravitational lensing, and their ordinary 'baryonic' matter, measured via its X-ray emission. Unfortunately, the information available from these systems is limited by their rarity. Constraints on the properties of dark matter, such as its interaction cross-section, are therefore restricted by uncertainties in the individual systems' impact velocity, impact parameter and orientation with respect to the line of sight. Here we develop a complementary, statistical measurement in which every piece of substructure falling into every massive cluster is treated as a bullet. We define 'bulleticity' as the mean separation between dark matter and ordinary matter, and we measure the signal in hydrodynamical simulations. The phase space of substructure orbits also exhibits symmetries that provide an equivalent control test. Any detection of bulleticity in real data would indicate a difference in the interaction cross-sections of baryonic and dark matter that may rule out hypotheses of non-particulate dark matter that are otherwise able to model individual systems. A subsequent measurement of bulleticity could constrain the dark matter cross-section. Even with conservative estimates, the existing Hubble Space Telescope archive should yield an independent constraint tighter than that from the bullet cluster. This technique is then trivially extendable to and benefits enormously from larger, future surveys.

Total cross section of furfural by electron impact: Experiment and theory.

PubMed

Traoré Dubuis, A; Verkhovtsev, A; Ellis-Gibbings, L; Krupa, K; Blanco, F; Jones, D B; Brunger, M J; García, G

2017-08-07

We present experimental total cross sections for electron scattering from furfural in the energy range from 10 to 1000 eV, as measured using a double electrostatic analyzer gas cell electron transmission experiment. These results are compared to theoretical data for furfural, as well as to experimental and theoretical values for the structurally similar molecules furan and tetrahydrofuran. The measured total cross section is in agreement with the theoretical results obtained by means of the independent-atom model with screening corrected additivity rule including interference method. In the region of higher electron energies, from 500 eV to 10 keV, the total electron scattering cross section is also estimated using a semi-empirical model based on the number of electrons and dipole polarizabilities of the molecular targets. Together with the recently measured differential and integral cross sections, and the furfural energy-loss spectra, the present total cross section data nearly complete the data set that is required for numerical simulation of low-energy electron processes in furfural, covering the range of projectile energies from a few electron volts up to 10 keV.

Total cross section of furfural by electron impact: Experiment and theory

NASA Astrophysics Data System (ADS)

Traoré Dubuis, A.; Verkhovtsev, A.; Ellis-Gibbings, L.; Krupa, K.; Blanco, F.; Jones, D. B.; Brunger, M. J.; García, G.

2017-08-01

We present experimental total cross sections for electron scattering from furfural in the energy range from 10 to 1000 eV, as measured using a double electrostatic analyzer gas cell electron transmission experiment. These results are compared to theoretical data for furfural, as well as to experimental and theoretical values for the structurally similar molecules furan and tetrahydrofuran. The measured total cross section is in agreement with the theoretical results obtained by means of the independent-atom model with screening corrected additivity rule including interference method. In the region of higher electron energies, from 500 eV to 10 keV, the total electron scattering cross section is also estimated using a semi-empirical model based on the number of electrons and dipole polarizabilities of the molecular targets. Together with the recently measured differential and integral cross sections, and the furfural energy-loss spectra, the present total cross section data nearly complete the data set that is required for numerical simulation of low-energy electron processes in furfural, covering the range of projectile energies from a few electron volts up to 10 keV.

Measurement of the multi-TeV neutrino interaction cross-section with IceCube using Earth absorption

NASA Astrophysics Data System (ADS)

Aartsen, M. G.; Hill, G. C.; Kyriacou, A.; Robertson, S.; Wallace, A.; Whelan, B. J.; Ackermann, M.; Bernardini, E.; Blot, S.; Bradascio, F.; Bretz, H.-P.; Brostean-Kaiser, J.; Franckowiak, A.; Jacobi, E.; Karg, T.; Kintscher, T.; Kunwar, S.; Nahnhauer, R.; Satalecka, K.; Spiering, C.; Stachurska, J.; Stasik, A.; Strotjohann, N. L.; Terliuk, A.; Usner, M.; van Santen, J.; Adams, J.; Bagherpour, H.; Aguilar, J. A.; Ansseau, I.; Heereman, D.; Meagher, K.; Meures, T.; O'Murchadha, A.; Pinat, E.; Raab, C.; Ahlers, M.; Koskinen, D. J.; Larson, M. J.; Medici, M.; Rameez, M.; Ahrens, M.; Bohm, C.; Dumm, J. P.; Finley, C.; Flis, S.; Hultqvist, K.; Walck, C.; Zoll, M.; Al Samarai, I.; Bron, S.; Carver, T.; Christov, A.; Montaruli, T.; Altmann, D.; Anton, G.; Glüsenkamp, T.; Katz, U.; Kittler, T.; Tselengidou, M.; Andeen, K.; Plum, M.; Anderson, T.; Delaunay, J. J.; Dunkman, M.; Eller, P.; Huang, F.; Keivani, A.; Lanfranchi, J. L.; Pankova, D. V.; Teši´, G.; Turley, C. F.; Weiss, M. J.; Argüelles, C.; Axani, S.; Collin, G. H.; Conrad, J. M.; Moulai, M.; Auffenberg, J.; Brenzke, M.; Glauch, T.; Haack, C.; Kalaczynski, P.; Koschinsky, J. P.; Leuermann, M.; Rädel, L.; Reimann, R.; Rongen, M.; Sälzer, T.; Schoenen, S.; Schumacher, L.; Stettner, J.; Vehring, M.; Vogel, E.; Wallraff, M.; Waza, A.; Wiebusch, C. H.; Bai, X.; Barron, J. P.; Giang, W.; Grant, D.; Kopper, C.; Moore, R. W.; Nowicki, S. C.; Herrera, S. E. Sanchez; Sarkar, S.; Wandler, F. D.; Weaver, C.; Wood, T. R.; Woolsey, E.; Yanez, J. P.; Barwick, S. W.; Yodh, G.; Baum, V.; Böser, S.; di Lorenzo, V.; Eberhardt, B.; Ehrhardt, T.; Köpke, L.; Krückl, G.; Momenté, G.; Peiffer, P.; Sandroos, J.; Steuer, A.; Wiebe, K.; Bay, R.; Filimonov, K.; Price, P. B.; Woschnagg, K.; Beatty, J. J.; Tjus, J. Becker; Bos, F.; Eichmann, B.; Kroll, M.; Schöneberg, S.; Tenholt, F.; Becker, K.-H.; Bindig, D.; Helbing, K.; Hickford, S.; Hoffmann, R.; Lauber, F.; Naumann, U.; Pollmann, A. Obertacke; Soldin, D.; Benzvi, S.; Cross, R.; Berley, D.; Blaufuss, E.; Cheung, E.; Felde, J.; Friedman, E.; Hellauer, R.; Hoffman, K. D.; Maunu, R.; Olivas, A.; Schmidt, T.; Song, M.; Sullivan, G. W.; Besson, D. Z.; Binder, G.; Klein, S. R.; Miarecki, S.; Palczewski, T.; Tatar, J.; Börner, M.; Fuchs, T.; Hünnefeld, M.; Meier, M.; Menne, T.; Pieloth, D.; Rhode, W.; Ruhe, T.; Sandrock, A.; Schlunder, P.; Soedingrekso, J.; Werthebach, J.; Bose, D.; Dujmovic, H.; in, S.; Jeong, M.; Kang, W.; Kim, J.; Rott, C.; Botner, O.; Burgman, A.; Hallgren, A.; Pérez de Los Heros, C.; Unger, E.; Bourbeau, J.; Braun, J.; Casey, J.; Chirkin, D.; Day, M.; Desiati, P.; Díaz-Vélez, J. C.; Fahey, S.; Ghorbani, K.; Griffith, Z.; Halzen, F.; Hanson, K.; Hokanson-Fasig, B.; Hoshina, K.; Jero, K.; Karle, A.; Kauer, M.; Kelley, J. L.; Kheirandish, A.; Liu, Q. R.; Luszczak, W.; Mancina, S.; McNally, F.; Merino, G.; Schneider, A.; Tobin, M. N.; Tosi, D.; Ty, B.; Vandenbroucke, J.; Wandkowsky, N.; Wendt, C.; Westerhoff, S.; Wille, L.; Wolf, M.; Wood, J.; Xu, D. L.; Yuan, T.; Brayeur, L.; Casier, M.; de Clercq, C.; de Vries, K. D.; de Wasseige, G.; Kunnen, J.; Lünemann, J.; Maggi, G.; Toscano, S.; van Eijndhoven, N.; Clark, K.; Classen, L.; Kappes, A.; Coenders, S.; Huber, M.; Krings, K.; Rea, I. C.; Resconi, E.; Turcati, A.; Cowen, D. F.; de André, J. P. A. M.; Deyoung, T.; Hignight, J.; Lennarz, D.; Mahn, K. B. M.; Micallef, J.; Neer, G.; Rysewyk, D.; Dembinski, H.; Evenson, P. A.; Gaisser, T. K.; Gonzalez, J. G.; Koirala, R.; Pandya, H.; Seckel, D.; Stanev, T.; Tilav, S.; De Ridder, S.; Labare, M.; Ryckbosch, D.; van Driessche, W.; Vanheule, S.; Vraeghe, M.; de With, M.; Hebecker, D.; Kolanoski, H.; Fazely, A. R.; Ter-Antonyan, S.; Xu, X. W.; Gallagher, J.; Gerhardt, L.; Goldschmidt, A.; Nygren, D. R.; Przybylski, G. T.; Stezelberger, T.; Stokstad, R. G.; Ishihara, A.; Kim, M.; Kuwabara, T.; Lu, L.; Mase, K.; Relich, M.; Stößl, A.; Yoshida, S.; Japaridze, G. S.; Jones, B. J. P.; Kiryluk, J.; Lesiak-Bzdak, M.; Niederhausen, H.; Xu, Y.; Kohnen, G.; Kopper, S.; Nakarmi, P.; Pepper, J. A.; Toale, P. A.; Williams, D. R.; Kowalski, M.; Kurahashi, N.; Relethford, B.; Richman, M.; Wills, L.; Madsen, J.; Seunarine, S.; Spiczak, G. M.; Maruyama, R.; Rawlins, K.; Sarkar, S.; Sutherland, M.; Taboada, I.; Tung, C. F.; IceCube Collaboration

2017-11-01

Neutrinos interact only very weakly, so they are extremely penetrating. The theoretical neutrino-nucleon interaction cross-section, however, increases with increasing neutrino energy, and neutrinos with energies above 40 teraelectronvolts (TeV) are expected to be absorbed as they pass through the Earth. Experimentally, the cross-section has been determined only at the relatively low energies (below 0.4 TeV) that are available at neutrino beams from accelerators. Here we report a measurement of neutrino absorption by the Earth using a sample of 10,784 energetic upward-going neutrino-induced muons. The flux of high-energy neutrinos transiting long paths through the Earth is attenuated compared to a reference sample that follows shorter trajectories. Using a fit to the two-dimensional distribution of muon energy and zenith angle, we determine the neutrino-nucleon interaction cross-section for neutrino energies 6.3-980 TeV, more than an order of magnitude higher than previous measurements. The measured cross-section is about 1.3 times the prediction of the standard model, consistent with the expectations for charged- and neutral-current interactions. We do not observe a large increase in the cross-section with neutrino energy, in contrast with the predictions of some theoretical models, including those invoking more compact spatial dimensions or the production of leptoquarks. This cross-section measurement can be used to set limits on the existence of some hypothesized beyond-standard-model particles, including leptoquarks.

Measurement of the multi-TeV neutrino interaction cross-section with IceCube using Earth absorption.

PubMed

2017-11-30

Neutrinos interact only very weakly, so they are extremely penetrating. The theoretical neutrino-nucleon interaction cross-section, however, increases with increasing neutrino energy, and neutrinos with energies above 40 teraelectronvolts (TeV) are expected to be absorbed as they pass through the Earth. Experimentally, the cross-section has been determined only at the relatively low energies (below 0.4 TeV) that are available at neutrino beams from accelerators. Here we report a measurement of neutrino absorption by the Earth using a sample of 10,784 energetic upward-going neutrino-induced muons. The flux of high-energy neutrinos transiting long paths through the Earth is attenuated compared to a reference sample that follows shorter trajectories. Using a fit to the two-dimensional distribution of muon energy and zenith angle, we determine the neutrino-nucleon interaction cross-section for neutrino energies 6.3-980 TeV, more than an order of magnitude higher than previous measurements. The measured cross-section is about 1.3 times the prediction of the standard model, consistent with the expectations for charged- and neutral-current interactions. We do not observe a large increase in the cross-section with neutrino energy, in contrast with the predictions of some theoretical models, including those invoking more compact spatial dimensions or the production of leptoquarks. This cross-section measurement can be used to set limits on the existence of some hypothesized beyond-standard-model particles, including leptoquarks.

A course-based cross-cultural interaction among pharmacy students in Qatar and Canada.

PubMed

Wilby, Kyle John; Taylor, Jeff; Khalifa, Sherief I; Jorgenson, Derek

2015-03-25

To develop, implement, and evaluate a course-based, cross-cultural student interaction using real-time videoconferencing between universities in Canada and Qatar. A professional skills simulation practice session on smoking cessation was run for students in Qatar (n=22) and Canada (n=22). Students role played cases in small group situations and then interacted with colleagues from the other country regarding culturally challenging situations and communication strategies. Students were assessed on analytical content and communication skills through faculty member and peer evaluation. Cultural competency outcomes were assessed using a postsession survey. Overall, 92.3% of respondents agreed that learning was enhanced through the cross-cultural exchange, and 94.9% agreed that insight was gained into the health-related issues and needs of people from another culture. A course-based, cross-cultural interaction was an effective method to incorporate cultural competency principles into student learning. Future initiatives should increase direct student interaction and focus on culturally sensitive topics.

A Course-based Cross-Cultural Interaction among Pharmacy Students in Qatar and Canada

PubMed Central

Taylor, Jeff; Khalifa, Sherief I.; Jorgenson, Derek

2015-01-01

Objective. To develop, implement, and evaluate a course-based, cross-cultural student interaction using real-time videoconferencing between universities in Canada and Qatar. Design. A professional skills simulation practice session on smoking cessation was run for students in Qatar (n=22) and Canada (n=22). Students role played cases in small group situations and then interacted with colleagues from the other country regarding culturally challenging situations and communication strategies. Assessment. Students were assessed on analytical content and communication skills through faculty member and peer evaluation. Cultural competency outcomes were assessed using a postsession survey. Overall, 92.3% of respondents agreed that learning was enhanced through the cross-cultural exchange, and 94.9% agreed that insight was gained into the health-related issues and needs of people from another culture. Conclusion. A course-based, cross-cultural interaction was an effective method to incorporate cultural competency principles into student learning. Future initiatives should increase direct student interaction and focus on culturally sensitive topics. PMID:25861107

Self-reported musculoskeletal disorder pain: The role of job hazards and work-life interaction.

PubMed

Weale, Victoria P; Wells, Yvonne; Oakman, Jodi

2018-02-01

Previous research identified an association between work-family conflict and musculoskeletal pain. This study explores how the work-life interface might affect pain experienced by residential aged care staff. A cross-sectional survey of 426 employees in residential aged care was analyzed to assess the impacts of workplace hazards, work-family conflict, and work-life balance on self-reported musculoskeletal pain. Work-family conflict acts as a mediator of the relationships between workplace hazards and the total number of body regions at which musculoskeletal pain was experienced. Work-life balance only acts as a mediator for particular hazards and only if work-family conflict is not taken into account. Addressing work-life interaction, and in particular work-family conflict, warrants further investigation as a legitimate means through which musculoskeletal disorder risk can be reduced. Policies and practices to improve work-life interaction and reduce work-family conflict should be considered as integral components of musculoskeletal disorder risk management strategies. © 2017 Wiley Periodicals, Inc.

Time and frequency pump-probe multiplexing to enhance the signal response of Brillouin optical time-domain analyzers.

PubMed

Soto, Marcelo A; Ricchiuti, Amelia Lavinia; Zhang, Liang; Barrera, David; Sales, Salvador; Thévenaz, Luc

2014-11-17

A technique to enhance the response and performance of Brillouin distributed fiber sensors is proposed and experimentally validated. The method consists in creating a multi-frequency pump pulse interacting with a matching multi-frequency continuous-wave probe. To avoid nonlinear cross-interaction between spectral lines, the method requires that the distinct pump pulse components and temporal traces reaching the photo-detector are subject to wavelength-selective delaying. This way the total pump and probe powers launched into the fiber can be incrementally boosted beyond the thresholds imposed by nonlinear effects. As a consequence of the multiplied pump-probe Brillouin interactions occurring along the fiber, the sensor response can be enhanced in exact proportion to the number of spectral components. The method is experimentally validated in a 50 km-long distributed optical fiber sensor augmented to 3 pump-probe spectral pairs, demonstrating a signal-to-noise ratio enhancement of 4.8 dB.

Self-interacting dark matter

NASA Astrophysics Data System (ADS)

Mavromatos, Nick E.; Argüelles, Carlos R.; Ruffini, Remo; Rueda, Jorge A.

Self-interacting dark matter (SIDM) is a hypothetical form of dark matter (DM), characterized by relatively strong (compared to the weak interaction strength) self-interactions (SIs), which has been proposed to resolve a number of issues concerning tensions between simulations and observations at the galactic or smaller scales. We review here some recent developments discussed at the 14th Marcel Grossmann Meeting (MG14), paying particular attention to restrictions on the SIDM (total) cross-section from using novel observables in merging galactic structures, as well as the rôle of SIDM on the Milky Way halo and its central region. We report on some interesting particle-physics inspired SIDM models that were discussed at MG14, namely the glueball DM, and a right-handed neutrino DM (with mass of a few tens of keV, that may exist in minimal extensions of the standard model (SM)), interacting among themselves via vector bosons mediators in the dark sector. A detailed phenomenology of the latter model on galactic scales, as well as the potential role of the right handed neutrinos in alleviating some of the small-scale cosmology problems, namely the discrepancies between observations and numerical simulations within standard ΛCDM and ΛWDM cosmologies are reported.

Photoeffect cross sections of several rare-earth elements for 323-keV photons

NASA Astrophysics Data System (ADS)

Umesh, T. K.; Anasuya, S. J.; Shylaja Kumari, J.; Gowda, Channe; Gopinathan Nair, K. P.; Gowda, Ramakrishna

1992-02-01

Total-attenuation cross sections of the oxides of rare-earth elements such as La, Ce, Pr, Nd, Sm, Gd, Dy, Ho, and Er, and also NaNO3 and NaNO2 have been measured in a narrow-beam geometry setup at 323 keV. The total-attenuation cross section for oxygen was obtained as the difference in NaNO3 and NaNO2 cross sections. Using this, the total-attenuation cross sections of the individual lanthanides have been obtained with the aid of the mixture rule. From these, the photoeffect cross sections were derived by subtracting the scattering contribution. These values are found to agree well with Scofield's theoretical data [University of California Report No. UCRL 51326, 1973 (unpublished)].

The influence of interactions between accommodation and convergence on the lag of accommodation.

PubMed

Schor, C

1999-03-01

Several models of myopia predict that growth of axial length is stimulated by blur. Accommodative lag has been suggested as an important source of blur in the development of myopia and this study has modeled how cross-link interactions between accommodation and convergence might interact with uncorrected distance heterophoria and refractive error to influence accommodative lag. Accommodative lag was simulated with two models of interactions between accommodation and convergence (one with and one without adaptable tonic elements). Simulations of both models indicate that both uncorrected hyperopia and esophoria increase the lag of accommodative and uncorrected myopia and exophoria decrease the lag or introduce a lead of accommodation in response to the near (40 cm) stimulus. These effects were increased when gain of either cross-link, accommodative convergence (AC/A) or convergence accommodation (CA/C), was increased within a moderate range of values while the other was fixed at a normal value (clamped condition). These effects were exaggerated when both the AC/A and CA/C ratios were increased (covaried condition) and affects of cross-link gain were negated when an increase of one cross-link (e.g. AC/A) was accompanied by a reduction of the other cross-link (e.g. CA/C) (reciprocal condition). The inclusion of tonic adaptation in the model reduced steady state errors of accommodation for all conditions except when the AC/A ratio was very high (2 MA/D). Combinations of cross-link interactions between accommodation and convergence that resemble either clamped or reciprocal patterns occur naturally in clinical populations. Simulations suggest that these two patterns of abnormal cross-link interactions could affect the progression of myopia differently. Adaptable tonic accommodation and tonic vergence could potentially reduce the progression of myopia by reducing the lag of accommodation.

Analysis of drug use in institutionalized individuals with intellectual disability and tube feeding.

PubMed

Joos, Elke; Mehuys, Els; Remon, Jean Paul; Van Winckel, Myriam; Boussery, Koen

2016-04-01

Little is known about the medication used by people with intellectual disabilities (ID) and enteral feeding tube (EFT). However, in light of the complexity associated with drug administration through EFT, data on medication use in this population may be helpful in the development of practical guidelines and staff training initiatives. A cross-sectional, observational study was conducted in six Belgian residential care facilities (RCFs) for individuals with ID. Anonymized medication records of all residents receiving chronic medication through EFT were collected (n = 156). All chronic drugs were categorized according to the ATC classification, and medication records were checked for potential major drug-drug interactions (DDI). The 156 residents used a total of 1029 chronic drugs via EFT, with a median of six drugs per resident (range 1-14). A total of 148 different drug molecules were identified, belonging to 38 main ATC therapeutic groups (ATC level 2). Antiepileptics, drugs for constipation and drugs for acid-related disorders were the most frequently used groups. Seventy-four of the 156 screened medication records (47%) contained at least one potential DDI; in total, 116 potential interactions were identified, which represent 38 different interacting drug pairs. This study describes medication use through EFT among people with ID in Belgian RCFs, with antiepileptics being the most frequently used group. Our study also demonstrated that a high number of drugs is administered through EFT, and that the number of potential DDIs is high. These observations warrant an increased attention for drug administration through the EFT in individuals with ID.

Large-amplitude nuclear motion formulated in terms of dissipation of quantum fluctuations

NASA Astrophysics Data System (ADS)

Kuzyakin, R. A.; Sargsyan, V. V.; Adamian, G. G.; Antonenko, N. V.

2017-01-01

The potential-barrier penetrability and quasi-stationary thermal-decay rate of a metastable state are formulated in terms of microscopic quantum diffusion. Apart from linear coupling in momentum between the collective and internal subsystems, the formalism embraces the more general case of linear couplings in both the momentum and the coordinates. The developed formalism is then used for describing the process of projectile-nucleus capture by a target nucleus at incident energies near and below the Coulomb barrier. The capture partial probability, which determines the cross section for formation of a dinuclear system, is derived in analytical form. The total and partial capture cross sections, mean and root-mean-square angular momenta of the formed dinuclear system, astrophysical -factors, logarithmic derivatives, and barrier distributions are derived for various reactions. Also investigated are the effects of nuclear static deformation and neutron transfer between the interacting nuclei on the capture cross section and its isotopic dependence, and the entrance-channel effects on the capture process. The results of calculations for reactions involving both spherical and deformed nuclei are in good agreement with available experimental data.

A cross-cultural comparison of tonal synchrony and pitch imitation in the vocal dialogs of Belgian Flemish-speaking and Mexican Spanish-speaking mother-infant dyads.

PubMed

Van Puyvelde, Martine; Loots, Gerrit; Gillisjans, Lobcke; Pattyn, Nathalie; Quintana, Carmen

2015-08-01

This study reports a cross-cultural comparison of the vocal pitch patterns of 15 Mexican Spanish-speaking and 15 Belgian Flemish-speaking dyads, recorded during 5min of free-play in a laboratory setting. Both cultures have a tradition of dyadic face-to-face interaction but differ in language origins (i.e., Romanic versus Germanic). In total, 374 Mexican and 558 Flemish vocal exchanges were identified, analyzed and compared for their incidence of tonal synchrony (harmonic/pentatonic series), non-tonal synchrony (with/without imitations) and pitch and/or interval imitations. The main findings revealed that dyads in both cultures rely on tonal synchrony using similar pitch ratios and timing patterns. However, there were significant differences in the infants' vocal pitch imitation behavior. Additional video-analyzes on the contingency patterns involved in pitch imitation showed a cross-cultural difference in the maternal selective reinforcement of pitch imitation. The results are interpreted with regard to linguistic, developmental and cultural aspects and the 'musilanguage' model. Copyright © 2015 Elsevier Inc. All rights reserved.

Anapole dark matter annihilation into photons

NASA Astrophysics Data System (ADS)

Latimer, David C.

2017-05-01

In models of anapole dark matter (DM), the DM candidate is a Majorana fermion whose primary interaction with standard model (SM) particles is through an anapole coupling to off-shell photons. As such, at tree-level, anapole DM undergoes p-wave annihilation into SM charged fermions via a virtual photon. But, generally, Majorana fermions are polarizable, coupling to two real photons. This fact admits the possibility that anapole DM can annihilate into two photons in an s-wave process. Using an explicit model, we compute both the tree-level and diphoton contributions to the anapole DM annihilation cross section. Depending on model parameters, the s-wave process can either rival or be dwarfed by the p-wave contribution to the total annihilation cross section. Subjecting the model to astrophysical upper bounds on the s-wave annihilation mode, we rule out the model with large s-wave annihilation.

Electron impact ionization of plasma important SiClX (X = 1-4) molecules: theoretical cross sections

NASA Astrophysics Data System (ADS)

Kothari, Harshit N.; Pandya, Siddharth H.; Joshipura, K. N.

2011-06-01

Electron impact ionization of SiClX (X = 1-4) molecules is less studied but an important process for understanding and modelling the interactions of silicon-chlorine plasmas with different materials. The SiCl3 radical is a major chloro-silicon species involved in the CVD (chemical vapour deposition) of silicon films from SiCl4/Ar microwave plasmas. We report in this paper the total ionization cross sections for electron collisions on these silicon compounds at incident energies from the ionization threshold to 2000 eV. We employ the 'complex scattering potential-ionization contribution' method and identify the relative importance of various channels, with ionization included in the cumulative inelastic scattering. New results are also presented on these exotic molecular targets. This work is significant in view of the paucity of theoretical studies on the radicals SiClX (X = 1-3) and on SiCl4.

Electron and positron interaction with pyrimidine: A theoretical investigation

NASA Astrophysics Data System (ADS)

Sinha, Nidhi; Antony, Bobby

2018-03-01

Pyrimidine (C4H4N2) is considered as the building block of nucleobases, viz., cytosine, thymine and uracil. They provide a blueprint for probing the scattering of radiation by DNA and RNA bases. In this article, we report the elastic and total scattering cross-sections for electron and positron scattering from the pyrimidine molecule, employing a spherical complex optical potential (SCOP) formalism for an extensive energy range of 10 eV to 5 keV. In the case of positron scattering, the original SCOP formalism is modified to adequately solve the positron-target dynamics. Moreover, a reasonable agreement is observed between the present results and other available datasets, for both electron and positron scattering. The cross-sections for electron and positron impact scattering by pyrimidine are necessary input data for codes that seek to simulate radiation damage, and hence are useful to model biomolecular systems.

Electron capture in collisions of N+ with H and H+ with N

NASA Astrophysics Data System (ADS)

Lin, C. Y.; Stancil, P. C.; Gu, J. P.; Buenker, R. J.; Kimura, M.

2005-06-01

Charge-transfer processes due to collisions of N+ with atomic hydrogen and H+ with atomic nitrogen are investigated using the quantum-mechanical molecular-orbital close-coupling (MOCC) method. The MOCC calculations utilize ab initio adiabatic potentials and nonadiabatic radial and rotational couplings obtained with the multireference single- and double-excitation configuration interaction approach. Total and state-selective cross sections for the energy range 0.1meV/u-1keV/u are presented and compared with existing experimental and theoretical data. A large number of low-energy resonances are obtained for exoergic channels and near thresholds of endoergic channels. Rate coefficients are also obtained and comparison to previous calculations suggests nonadiabatic effects dominate for temperatures greater than 20 000 K, but that the spin-orbit interaction plays a major role for lower temperatures.

Interpretation of K+¯pair production in pp collisions

NASA Astrophysics Data System (ADS)

Dzyuba, A.; Büscher, M.; Hanhart, C.; Kleber, V.; Koptev, V.; Ströher, H.; Wilkin, C.

2008-10-01

A combined analysis of the published data on the pp → dK +¯0 reaction at excess energies of 47.4MeV and 104.7MeV is presented that takes into account final-state interactions in both the K +¯0 and ¯0 d channels. The strong attraction of the antikaons with nucleons, already noted for the pp → ppK + K - reaction, leads here to very different ¯0 d and K+d distributions, with the former being dominantly in an s -wave and the latter in a p -wave. Evidence is also found from the K +¯0 distributions for the production of the a 0 +(980) scalar resonance. The inclusion of both final-state interactions improves the description of the energy dependence of the pp → dK +¯0 total cross-section.

Positronium collisions with molecular nitrogen

NASA Astrophysics Data System (ADS)

Wilde, R. S.; Fabrikant, I. I.

2018-05-01

For many atomic and molecular targets positronium (Ps) scattering looks very similar to electron scattering if total scattering cross sections are plotted as functions of the projectile velocity. Recently this similarity was observed for the resonant scattering by the N2 molecule. For correct treatment of Ps-molecule scattering incorporation of the exchange interaction and short-range correlations is of paramount importance. In the present work we have used a free-electron-gas model to describe these interactions in collisions of Ps with the N2 molecule. The results agree reasonably well with the experiment, but the position of the resonance is somewhat shifted towards lower energies, probably due to the fixed-nuclei approximation employed in the calculations. The partial-wave analysis of the resonant peak shows that its composition is more complex than in the case of e -N2 scattering.

Target correlation effects on neutron-nucleus total, absorption, and abrasion cross sections

NASA Technical Reports Server (NTRS)

Cucinotta, Francis A.; Townsend, Lawrence W.; Wilson, John W.

1991-01-01

Second order optical model solutions to the elastic scattering amplitude were used to evaluate total, absorption, and abrasion cross sections for neutron nucleus scattering. Improved agreement with experimental data for total and absorption cross sections is found when compared with first order (coherent approximation) solutions, especially below several hundred MeV. At higher energies, the first and second order solutions are similar. There are also large differences in abrasion cross section calculations; these differences indicate a crucial role for cluster knockout in the abrasion step.

ELASTIC SCATTERING ANGULAR DISTRIBUTIONS AND TOTAL REACTION CROSS SECTIONS FOR THE INTERACTION OF 12.8 Mev DEUTERONS WITH Ni$sup 58$ AND Ni$sup 60$ NUCLEI

DOE Office of Scientific and Technical Information (OSTI.GOV)

Budzanowski, A.; Grotowski, K.

1962-10-15

Recentiy optical model analysis has been applied to fit the experimental angular distribution data of the elastic scattering of deuterons by nuclei. In view of a considerable dependence of sigma /sub R/ on the shape of the real and imaginary part of the potential at the nuclear surface, it was thought worthwhile to measure both sigma /sub el/ ( theta ) and sigma /sub R/ for 12.8 Mev deuterons on targets of separated Ni/sup 58/ and Ni/sup 60/ isotopes. (W.D.M.)

Initial Results of Interdisciplinary Science Enabled by Eclipse 2017: NASA Perspective

NASA Astrophysics Data System (ADS)

Guhathakurta, M.

2017-12-01

The exceptionally long path over land of the August 21st total and partial solar eclipse provided an unprecedented opportunity for cross disciplinary studies of the sun, moon, Earth, and their interactions. NASA supported research using ground-based measurements, balloons and planes that "chased" the eclipse as well as data taken from a vast array of orbiting spacecraft, all of which helped scientists take continuous measurements of the sun and the effects of the eclipse on the ionosphere and Earth for relatively long periods of time. This talk will summarize some of the initial findings from these research.

Partial Photoneutron Cross Sections for 207,208Pb

NASA Astrophysics Data System (ADS)

Kondo, T.; Utsunomiya, H.; Goriely, S.; Iwamoto, C.; Akimune, H.; Yamagata, T.; Toyokawa, H.; Harada, H.; Kitatani, F.; Lui, Y.-W.; Hilaire, S.; Koning, A. J.

2014-05-01

Using linearly-polarized laser-Compton scattering γ-rays, partial E1 and M1 photoneutron cross sections along with total cross sections were determined for 207,208Pb at four energies near neutron threshold by measuring anisotropies in photoneutron emission. Separately, total photoneutron cross sections were measured for 207,208Pb with a high-efficiency 4π neutron detector. The partial cross section measurement provides direct evidence for the presence of pygmy dipole resonance (PDR) in 207,208Pb in the vicinity of neutron threshold. The strength of PDR amounts to 0.32%-0.42% of the Thomas-Reiche-Kuhn sum rule. Several μN2 units of B(M1)↑ strength were observed in 207,208Pb just above neutron threshold, which correspond to M1 cross sections less than 10% of the total photoneutron cross sections.

Tuning gain and bandwidth of traveling wave tubes using metamaterial beam-wave interaction structures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lipton, Robert, E-mail: lipton@math.lsu.edu; Polizzi, Anthony, E-mail: polizzi@math.lsu.edu

We employ metamaterial beam-wave interaction structures for tuning the gain and bandwidth of short traveling wave tubes. The interaction structures are made from metal rings of uniform cross section, which are periodically deployed along the length of the traveling wave tube. The aspect ratio of the ring cross sections is adjusted to control both gain and bandwidth. The frequency of operation is controlled by the filling fraction of the ring cross section with respect to the size of the period cell.

Deuteron-induced reactions on Ni isotopes up to 60 MeV

NASA Astrophysics Data System (ADS)

Avrigeanu, M.; Šimečková, E.; Fischer, U.; Mrázek, J.; Novak, J.; Štefánik, M.; Costache, C.; Avrigeanu, V.

2016-07-01

Background: The high complexity of the deuteron-nucleus interaction from the deuteron weak binding energy of 2.224 MeV is also related to a variety of reactions induced by the deuteron-breakup (BU) nucleons. Thus, specific noncompound processes as BU and direct reactions (DR) make the deuteron-induced reactions so different from reactions with other incident particles. The scarce consideration of only pre-equilibrium emission (PE) and compound-nucleus (CN) mechanisms led to significant discrepancies with experimental results so that recommended reaction cross sections of high-priority elements as, e.g., Ni have mainly been obtained by fit of the data. Purpose: The unitary and consistent BU and DR account in deuteron-induced reactions on natural nickel may take advantage of an extended database for this element, including new accurate measurements of particular reaction cross sections. Method: The activation cross sections of 64,61,60Cu, Ni,5765, and 55,56,57,58,59m,60Co nuclei for deuterons incident on natural Ni at energies up to 20 MeV, were measured by the stacked-foil technique and high-resolution gamma spectrometry using U-120M cyclotron of CANAM, NPI CAS. Then, within an extended analysis of deuteron interactions with Ni isotopes up to 60 MeV, all processes from elastic scattering until the evaporation from fully equilibrated compound system have been taken into account while an increased attention is paid especially to the BU and DR mechanisms. Results: The deuteron activation cross-section analysis, completed by consideration of the PE and CN contributions corrected for decrease of the total-reaction cross section from the leakage of the initial deuteron flux towards BU and DR processes, is proved satisfactory for the first time to all available data. Conclusions: The overall agreement of the measured data and model calculations validates the description of nuclear mechanisms taken into account for deuteron-induced reactions on Ni, particularly the BU and DR that should be considered explicitly.

Calculations of Total Classical Cross Sections for a Central Field

NASA Astrophysics Data System (ADS)

Tsyganov, D. L.

2018-07-01

In order to find the total collision cross-section a direct method of the effective potential (EPM) in the framework of classical mechanics was proposed. EPM allows to over come both the direct scattering problem (calculation of the total collision cross-section) and the inverse scattering problem (reconstruction of the scattering potential) quickly and effectively. A general analytical expression was proposed for the generalized Lennard-Jones potentials: (6-3), (9-3), (12-3), (6-4), (8-4), (12-4), (8-6), (12-6), (18-6). The values for the scattering potential of the total cross section for pairs such as electron-N2, N-N, and O-O2 were obtained in a good approximation.

Ionizing Collisions of Electrons with Radical Species OH, H2 O2 and HO2; Theoretical Calculations

NASA Astrophysics Data System (ADS)

Joshipura, K. N.; Pandya, S. H.; Vaishnav, B. G.; Patel, U. R.

2016-05-01

In this paper we present our calculated total ionization cross sections (TICS) of electron impact on radical targets OH, H2 O2 and HO2 at energies from threshold to 2000 eV. Reactive species such as these pose difficulties in measurements of electron scattering cross sections. No measured data have been reported in this regard except an isolated TICS measurement on OH radical, and hence the present work on the title radicals hold significance. These radical species are present in an environment in which water molecules undergo dissociation (neutral or ionic) in interactions with photons or electrons. The embedding environments could be quite diverse, ranging from our atmosphere to membranes of living cells. Ionization of OH, H2 O2 or HO2 can give rise to further chemistry in the relevant bulk medium. Therefore, it is appropriate and meaningful to examine electron impact ionization of these radicals in comparison with that of water molecules, for which accurate da are available. For the OH target single-centre scattering calculations are performed by starting with a 4-term complex potential, that describes simultaneous elastic plus inelastic scattering. TICS are obtained from the total inelastic cross sections in the complex scattering potential - ionization contribution formalism , a well established method. For H2 O2 and HO2 targets, we employ the additivity rule with overlap or screening corrections. Detailed results will be presented in the Conference.

PIPE: a protein–protein interaction passage extraction module for BioCreative challenge

PubMed Central

Chu, Chun-Han; Su, Yu-Chen; Chen, Chien Chin; Hsu, Wen-Lian

2016-01-01

Identifying the interactions between proteins mentioned in biomedical literatures is one of the frequently discussed topics of text mining in the life science field. In this article, we propose PIPE, an interaction pattern generation module used in the Collaborative Biocurator Assistant Task at BioCreative V (http://www.biocreative.org/) to capture frequent protein-protein interaction (PPI) patterns within text. We also present an interaction pattern tree (IPT) kernel method that integrates the PPI patterns with convolution tree kernel (CTK) to extract PPIs. Methods were evaluated on LLL, IEPA, HPRD50, AIMed and BioInfer corpora using cross-validation, cross-learning and cross-corpus evaluation. Empirical evaluations demonstrate that our method is effective and outperforms several well-known PPI extraction methods. Database URL: PMID:27524807

Description of alpha-nucleus interaction cross sections for cosmic ray shielding studies

NASA Technical Reports Server (NTRS)

Cucinotta, Francis A.; Townsend, Lawrence W.; Wilson, John W.

1993-01-01

Nuclear interactions of high-energy alpha particles with target nuclei important for cosmic ray studies are discussed. Models for elastic, quasi-elastic, and breakup reactions are presented and compared with experimental data. Energy-dependent interaction cross sections and secondary spectra are presented based on theoretical models and the limited experimental data base.

Identification of novel direct protein-protein interactions by irradiating living cells with femtosecond UV laser pulses.

PubMed

Itri, Francesco; Monti, Daria Maria; Chino, Marco; Vinciguerra, Roberto; Altucci, Carlo; Lombardi, Angela; Piccoli, Renata; Birolo, Leila; Arciello, Angela

2017-10-07

The identification of protein-protein interaction networks in living cells is becoming increasingly fundamental to elucidate main biological processes and to understand disease molecular bases on a system-wide level. We recently described a method (LUCK, Laser UV Cross-linKing) to cross-link interacting protein surfaces in living cells by UV laser irradiation. By using this innovative methodology, that does not require any protein modification or cell engineering, here we demonstrate that, upon UV laser irradiation of HeLa cells, a direct interaction between GAPDH and alpha-enolase was "frozen" by a cross-linking event. We validated the occurrence of this direct interaction by co-immunoprecipitation and Immuno-FRET analyses. This represents a proof of principle of the LUCK capability to reveal direct protein interactions in their physiological environment. Copyright © 2017 Elsevier Inc. All rights reserved.

The Bilingual Language Interaction Network for Comprehension of Speech*

PubMed Central

Marian, Viorica

2013-01-01

During speech comprehension, bilinguals co-activate both of their languages, resulting in cross-linguistic interaction at various levels of processing. This interaction has important consequences for both the structure of the language system and the mechanisms by which the system processes spoken language. Using computational modeling, we can examine how cross-linguistic interaction affects language processing in a controlled, simulated environment. Here we present a connectionist model of bilingual language processing, the Bilingual Language Interaction Network for Comprehension of Speech (BLINCS), wherein interconnected levels of processing are created using dynamic, self-organizing maps. BLINCS can account for a variety of psycholinguistic phenomena, including cross-linguistic interaction at and across multiple levels of processing, cognate facilitation effects, and audio-visual integration during speech comprehension. The model also provides a way to separate two languages without requiring a global language-identification system. We conclude that BLINCS serves as a promising new model of bilingual spoken language comprehension. PMID:24363602

Total and Compound Formation Cross Sections for Americium Nuclei: Recommendations for Coupled-Channels Calculations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Escher, J. E.

Calculations for total cross sections and compound-nucleus (CN) formation cross sections for americium isotopes are described, for use in the 2017 NA-22 evaluation effort. The code ECIS 2006 was used in conjunction with Frank Dietrich's wrapper `runtemplate'.

Electron-impact total ionization cross sections of DNA sugar-phosphate backbone and an additivity principle

NASA Technical Reports Server (NTRS)

Huo, Winifred M.; Dateo, Christopher E.

2005-01-01

The improved binary-encounter dipole (iBED) model [W.M. Huo, Phys. Rev. A64, 042719-1 (2001)l is used to study the total ionization cross sections of the DNA sugar-phosphate backbone by electron impact. Calculations using neutral fragments found that the total ionization cross sections of C3' - and C5', -deoxyribose-phospate, two conformers of the sugar-phosphate backbone, are close to each other. Furthermore, the sum of the ionization cross sections of the separate deoxyribose and phosphate fragments is in close agreement with the C3' - and C5" -deoxyribose-phospate cross sections, differing by less than 10%. The result implies that certain properties of the-DNA, like the total singly ionization cross section, are localized properties and a building-up or additivity principle may apply. This allows us to obtain accurate properties of larger molecular systems built up from the results of smaller subsystem fragments. Calculations are underway using a negatively charged sugar-phosphate backbone with a metal counter-ion.

Re-visiting internet addiction among Taiwanese students: a cross-sectional comparison of students' expectations, online gaming, and online social interaction.

PubMed

Lee, Yuan-Hsuan; Ko, Chih-Hung; Chou, Chien

2015-04-01

Using expectancy theory, this study aimed at identifying the attitudinal/behavioral factors that explain the relationship between Internet expectancies and Internet addiction among Taiwanese adolescents. A total of 25,573 students (49.8% boys and 50.2% girls) across junior and senior high schools participated in the study. The students reported on their background characteristics, general expectations from the Internet, attitudes toward online social interaction and online gaming, preferences in online social interaction, and dys-controlled online gaming behavior. Structural equation modeling was used to examine the indirect effects of Internet expectancies on Internet addiction through these attitudinal/behavioral factors. The results showed that Internet expectancies positively predicted students' attitudes toward online games and online social interaction, which in turn predicted their respective preferences or dys-controlled behavior and Internet addiction. The indirect effect of Internet expectancies was higher on Internet addiction via attitudes toward online gaming and dys-controlled online gaming than via attitudes toward and preferences of online social interaction. The indirect effects exhibited a larger impact on boys than on girls. The authors recommend that the expectancies of online gaming and social interaction be addressed in efforts to prevent and attenuate the severity of adolescent Internet addiction.

Experimental study of low-energy charge transfer in nitrogen

NASA Technical Reports Server (NTRS)

Smith, A.

1979-01-01

Total charge transfer cross sections were obtained for the N2(+)-N2 system with relative translational ion energies between 9 and 441 eV. Data were obtained to examine the dependence of total cross section on ion energy. The effect of ion excitation on the cross sections was studied by varying the electron ionization energy in the mass spectrometer ion source over an electron energy range between 14.5 and 32.1 eV. The dependence of total cross section on the neutralization chamber gas pressure was examined by obtaining data at pressure values from 9.9 to 0.000199 torr. Cross section values obtained were compared with experimental and theoretical results of other investigations.

Measurement of inclusive and differential cross sections in the H → ZZ * → 4ℓ decay channel in pp collisions at $$ \\sqrt{s}=13 $$ TeV with the ATLAS detector

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aaboud, M.; Aad, G.; Abbott, B.

Inclusive and differential fiducial cross sections of Higgs boson production in proton-proton collisions are measured in the H → ZZ* → 4ℓ decay channel. The proton-proton collision data were produced at the Large Hadron Collider at a centre-of-mass energy of 13 TeV and recorded by the ATLAS detector in 2015 and 2016, corresponding to an integrated luminosity of 36.1 fb –1. The inclusive fiducial cross section in the H → ZZ* → 4ℓ decay channel is measured to be 3.62±0.50(stat) –0.20 +0.25 (sys) fb, in agreement with the Standard Model prediction of 2.91 ± 0.13 fb. The cross section ismore » also extrapolated to the total phase space including all Standard Model Higgs boson decays. Several differential fiducial cross sections are measured for observables sensitive to the Higgs boson production and decay, including kinematic distributions of jets produced in association with the Higgs boson. Good agreement is found between data and Standard Model predictions. The results are used to put constraints on anomalous Higgs boson interactions with Standard Model particles, using the pseudo-observable extension to the kappa-framework.« less

Measurement of inclusive and differential cross sections in the H → ZZ * → 4ℓ decay channel in pp collisions at $$ \\sqrt{s}=13 $$ TeV with the ATLAS detector

DOE PAGES

Aaboud, M.; Aad, G.; Abbott, B.; ...

2017-10-19

Inclusive and differential fiducial cross sections of Higgs boson production in proton-proton collisions are measured in the H → ZZ* → 4ℓ decay channel. The proton-proton collision data were produced at the Large Hadron Collider at a centre-of-mass energy of 13 TeV and recorded by the ATLAS detector in 2015 and 2016, corresponding to an integrated luminosity of 36.1 fb –1. The inclusive fiducial cross section in the H → ZZ* → 4ℓ decay channel is measured to be 3.62±0.50(stat) –0.20 +0.25 (sys) fb, in agreement with the Standard Model prediction of 2.91 ± 0.13 fb. The cross section ismore » also extrapolated to the total phase space including all Standard Model Higgs boson decays. Several differential fiducial cross sections are measured for observables sensitive to the Higgs boson production and decay, including kinematic distributions of jets produced in association with the Higgs boson. Good agreement is found between data and Standard Model predictions. The results are used to put constraints on anomalous Higgs boson interactions with Standard Model particles, using the pseudo-observable extension to the kappa-framework.« less

Linear attenuation coefficients of tissues from 1 keV to 150 keV

NASA Astrophysics Data System (ADS)

Böke, Aysun

2014-09-01

The linear attenuation coefficients and three interaction processes have been computed for liver, kidney, muscle, fat and for a range of x-ray energies from 1 keV to 150 keV. Molecular photoelectric absorption cross sections were calculated from atomic cross section data. Total coherent (Rayleigh) and incoherent (Compton) scattering cross sections were obtained by numerical integration over combinations of F2m(x) with the Thomson formula and Sm(x) with the Klein-Nishina formula, respectively. For the coherent (Rayleigh) scattering cross section calculations, molecular form factors were obtained from recent experimental data in the literature for values of x<1 Å-1 and from the relativistic modified atomic form factors for values of x≥1 Å-1. With the inclusion of molecular interference effects in the coherent (Rayleigh) scattering, more accurate knowledge of the scatter from these tissues will be provided. The number of elements involved in tissue composition is 5 for liver, 47 for kidney, 44 for muscle and 3 for fat. The results are compared with previously published experimental and theoretical linear attenuation coefficients. In general, good agreement is obtained. The molecular form factors and scattering functions and cross sections are incorporated into a Monte Carlo program. The energy distributions of x-ray photons scattered from tissues have been simulated and the results are presented.

2017 Total Solar Eclipse Science Briefing

NASA Image and Video Library

2017-06-21

During a June 21 media briefing from the Newseum in Washington, representatives from NASA, other federal agencies, and science organizations discussed the opportunity for scientific study offered by the total solar eclipse that will cross the U.S. on August 21. Over the course of 100 minutes, 14 states across the United States will experience more than two minutes of darkness in the middle of the day. Additionally, a partial eclipse will be viewable across all of North America. The eclipse will provide a unique opportunity to study the sun, Earth, moon and their interaction because of the eclipse’s long path over land coast to coast. Scientists will be able to take ground-based and airborne observations over a period of an hour and a half to complement the wealth of data and images provided by space assets.

Evaluation of Shielding Performance for Newly Developed Composite Materials

NASA Astrophysics Data System (ADS)

Evans, Beren Richard

This work details an investigation into the contributing factors behind the success of newly developed composite neutron shield materials. Monte Carlo simulation methods were utilized to assess the neutron shielding capabilities and secondary radiation production characteristics of aluminum boron carbide, tungsten boron carbide, bismuth borosilicate glass, and Metathene within various neutron energy spectra. Shielding performance and secondary radiation data suggested that tungsten boron carbide was the most effective composite material. An analysis of the macroscopic cross-section contributions from constituent materials and interaction mechanisms was then performed in an attempt to determine the reasons for tungsten boron carbide's success over the other investigated materials. This analysis determined that there was a positive correlation between a non-elastic interaction contribution towards a material's total cross-section and shielding performance within the thermal and epi-thermal energy regimes. This finding was assumed to be a result of the boron-10 absorption reaction. The analysis also determined that within the faster energy regions, materials featuring higher non-elastic interaction contributions were comparable to those exhibiting primarily elastic scattering via low Z elements. This allowed for the conclusion that composite shield success within higher energy neutron spectra does not necessitate the use elastic scattering via low Z elements. These findings suggest that the inclusion of materials featuring high thermal absorption properties is more critical to composite neutron shield performance than the presence of constituent materials more inclined to maximize elastic scattering energy loss.

Site-Specific Advantages in Skeletal Geometry and Strength at the Proximal Femur and Forearm in Young Female Gymnasts

PubMed Central

Dowthwaite, Jodi N.; Rosenbaum, Paula F.; Scerpella, Tamara A.

2012-01-01

Purpose We evaluated site-specific skeletal adaptation to loading during growth,comparing radius (RAD) and femoral neck (FN) DXA scans in young female gymnasts (GYM) and non-gymnasts (NON). Methods Subjects from an ongoing longitudinal study (8-26 yrs old) underwent annual DXA scans (proximal femur, forearm, total body) and anthropometry, completing maturity and physical activity questionnaires. This cross-sectional analysis used the most recent data meeting the following criteria: gynecological age ≤2.5 yrs post-menarche; GYM annual mean gymnastic exposure ≥5.0 h/wk in the prior year. Bone geometric and strength indices were derived from scans for 173 subjects (8-17 yrs old) via hip structural analysis (femoral narrow neck, NN) and similar radius formulae (1/3 and Ultradistal (UD)). Maturity was coded as M1 (Tanner I breast), M2 (pre-menarche, ≥Tanner II breast) or M3 (post-menarche). ANOVA and chi square compared descriptive data. Two factor ANCOVA adjusted for age, height, total body non-bone lean mass and percent body fat; significance was tested for main effects and interactions between gymnastic exposure and maturity. Results At the distal radius, GYM means were significantly greater than NON means for all variables (p<0.05). At the proximal femur, GYM exhibited narrower periosteal and endosteal dimensions, but greater indices of cortical thickness, BMC, aBMD and section modulus, with lower buckling ratio (p <0.05). However, significant interactions between maturity and loading were detected for the following: 1) FN bone mineral content (BMC), NN buckling ratio (GYM BMC advantages only in M1 and M3; for BMC and buckling ratio, M1 advantages were greatest; 2) 1/3 radius BMC, width, endosteal diameter, cortical cross-sectional area, section modulus (GYM advantages primarily post-menarche); 3) UD radius BMC and axial compressive strength (GYM advantages were larger with greater maturity, greatest post-menarche). Conclusions Maturity-specific comparisons suggested site-specific skeletal adaptation to loading during growth, with greater advantages at the radius versus the proximal femur. At the radius, GYM advantages included greater bone width, cortical cross-sectional area and cortical thickness; in contrast, at the femoral neck, GYM bone tissue cross-sectional area and cortical thickness were greater, but bone width was narrower than in NON. Future longitudinal analyses will evaluate putative maturity-specific differences. PMID:22342799

Kernel reconstruction methods for Doppler broadening — Temperature interpolation by linear combination of reference cross sections at optimally chosen temperatures

DOE PAGES

Ducru, Pablo; Josey, Colin; Dibert, Karia; ...

2017-01-25

This paper establishes a new family of methods to perform temperature interpolation of nuclear interactions cross sections, reaction rates, or cross sections times the energy. One of these quantities at temperature T is approximated as a linear combination of quantities at reference temperatures (T j). The problem is formalized in a cross section independent fashion by considering the kernels of the different operators that convert cross section related quantities from a temperature T 0 to a higher temperature T — namely the Doppler broadening operation. Doppler broadening interpolation of nuclear cross sections is thus here performed by reconstructing the kernelmore » of the operation at a given temperature T by means of linear combination of kernels at reference temperatures (T j). The choice of the L 2 metric yields optimal linear interpolation coefficients in the form of the solutions of a linear algebraic system inversion. The optimization of the choice of reference temperatures (T j) is then undertaken so as to best reconstruct, in the L∞ sense, the kernels over a given temperature range [T min,T max]. The performance of these kernel reconstruction methods is then assessed in light of previous temperature interpolation methods by testing them upon isotope 238U. Temperature-optimized free Doppler kernel reconstruction significantly outperforms all previous interpolation-based methods, achieving 0.1% relative error on temperature interpolation of 238U total cross section over the temperature range [300 K,3000 K] with only 9 reference temperatures.« less

Interracial Contact on College Campuses: Comparing and Contrasting Predictors of Cross-Racial Interaction and Interracial Friendship

ERIC Educational Resources Information Center

Bowman, Nicholas A.; Park, Julie J.

2014-01-01

Research on diversity in higher education has evolved to consider the nature of interracial contact and campus climate as well as the factors that may foster meaningful interactions. While some studies have explored predictors of cross-racial interaction (CRI) and interracial friendship (IRF), it remains unclear whether and how the same precollege…

Cultural Nuances, Assumptions, and the Butterfly Effect: Addressing the Unpredictability Caused by Unconscious Values Structures in Cross-Cultural Interactions

ERIC Educational Resources Information Center

Remer, Rory

2007-01-01

Cultural values, cross-cultural interaction patterns that are produced by dynamical (chaotic) systems, have a significant impact on interaction, particularly among and between people from different cultures. The butterfly effect, which states that small differences in initial conditions may have severe consequences for patterns in the long run,…

Study of pathway cross-talk interactions with NF-κB leading to its activation via ubiquitination or phosphorylation: A brief review.

PubMed

Ghosh, Sayantan; Dass, J Febin Prabhu

2016-06-10

NFκB has been known to be a necessary transcription factor for the functioning of nearly all cells in a living organism. For its proper functioning, it talks to several other molecular cofactors and interacts with their functionalities resulting in a convoluted cross talking mesh of signalling networks. To completely understand the working of nuclear factor-kappa B protein, one needs to understand the interactions that occur during its lifecycle, with cofactors from various biological processes. This study attempts to elaborate and bridge the gaps on the cross-talk interactions that NFkB is a part of, during its activation pathway. For this Cytoscape and its various plugins (Cytocopter, Allegro, AgilentLitSearch and Styles) are employed. Other related pathways were also collated and analysed for cross-talk between NfκB and interacting molecules. NFκB was found to mainly interact with E3 ubiquitin ligase, NIK, RIP, TCR, IRAK-1, TLR, TRAF-6, NLR and IL-1, details of which are discussed as a part of this study. Copyright © 2016 Elsevier B.V. All rights reserved.

The effects of stream crossings on total suspended sediment in North Carolina Piedmont forests

Treesearch

Johnny Boggs; Ge Sun; Steve McNulty

2017-01-01

This study determined total suspended sediment (TSS) at six stream crossings that represented a range of site conditions and forest operations in the Piedmont of North Carolina. Two wood and three steel bridgemats and one culvert were installed to cross the streams. The road classes for the crossings included four temporary skid trails and two permanent forest haul...

The relationship between elderly suicide rates and elderly dependency ratios: a cross-national study using data from the WHO data bank.

PubMed

Shah, Ajit; Padayatchi, Mellisha; Das, Kavita

2008-06-01

Cultural factors may influence cross-national variations in elderly suicide rates. A cross-national study examining the relationship between elderly suicide rates and elderly dependency ratios was conducted with the a priori unidirectional hypothesis that lower elderly dependency ratios (ratio of people over the age of 65 years to people under the age of 65 years) may imply a greater number of younger people being potentially available to provide support and respect to the elderly and to hold them in high esteem, and this would lead to a reduction in elderly suicide rates. Data on elderly suicide rates, and the total number of elderly and young people were ascertained from the World Health Organization website. Significant positive correlations were found between the natural logarithm of suicide rates, in both sexes in two elderly age-bands (65-74 years and 75+ years), and the elderly dependency ratio for males, females and both sexes combined. The impact of elderly dependency ratios on elderly suicide rates may interact with and be modified and mediated through cultural factors. The contribution of cross-national differences in cultural factors on elderly suicide rates require further study by formally measuring cultural factors with validated instruments.

Charm production by muons and its role in scale-noninvariance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gollin, G D

1981-01-01

Interactions of 209 GeV muons in the Multimuon Spectrometer at Fermilab have yielded more than 8 x 10/sup 4/ events with two muons in the final state. After reconstruction and cuts, the data contain 20,072 events with (81 +- 10)% attributed to the diffractive production of charmed states decaying to muons. The cross section for diffractive charm muoproduction is 6.9(+1.9,-1.4) nb where the error includes systematic uncertainties. Extrapolated to Q/sup 2/ = 0 with sigma(Q/sup 2/) = sigma(0)(1 + Q/sup 2//..lambda../sup 2/)/sup -2/, the effective cross section for 178 (100) GeV photons is 750(+180,-130) (560(+200,-120)) nb and the parameter ..lambda..more » is 3.3 +- 0.2 (2.9 +- 0.2) GeV/c. The ..nu.. dependence of the cross section is similar to that of the photon-gluon-fusion model. A first determination of the structure function for diffractive charm production indicates that charm accounts for approximately 1/3 of the scale-noninvariance observed in inclusive muon-nucleon scattering at low Bjorken x. Okubo-Zweig-Iizuka selection rules and unitarity allow the muon data to set a 90%-confidence lower limit on the psi N total cross section of 0.9 mb.« less

Depressive Symptomatology, Psychological Stress, and Ovarian Reserve: A Role for Psychological Factors in Ovarian Aging?

PubMed Central

Bleil, Maria E.; Adler, Nancy E.; Pasch, Lauri A.; Sternfeld, Barbara; Gregorich, Steven E.; Rosen, Mitchell P.; Cedars, Marcelle I.

2012-01-01

Objective To examine psychological factors in relation to antral follicle count (AFC), a marker of ovarian reserve, in a multiethnic sample of 683 pre-menopausal women in the Ovarian Aging (OVA) Study. Methods In cross-sectional analyses, linear regression was performed to determine whether AFC decline across women varied over levels of depression as well as depression in combination with psychological stress. The total and subscale scores of the Center for Epidemiological Studies Depression Scale (CESD) were used to measure depression and the Perceived Stress Scale was used to measure psychological stress. Results Following covariate-adjustment, the 2-way interaction of age-x-positive affect and the 3-way interaction of age-x-positive affect-x-stress were related to AFC (b = 0.047, p = .036; b = 0.012, p = .099, respectively). In stratified analyses, stress was related to AFC in women with low positive affect (b = −.070, p = .021) but not in women with high positive affect (b = .018, p = .54). AFC decline across women was progressively higher in women with low positive affect who reported low (−0.747 follicles/year), mid (−0.920 follicles/year), and high (−1.112 follicles/year) levels of stress. Results examining the CESD total and remaining subscale scores were all non-significant (p’s > .05). Conclusions Cross-sectional evidence suggests that 1) women with low positive affect may experience accelerated AFC decline and 2) low positive affect may be a vulnerability factor, or, alternatively, high positive affect may be a protective factor, in moderating the negative effects of psychological stress on AFC decline. PMID:22760086

Simulated interactions of pedestrian crossings and motorized vehicles in residential areas

NASA Astrophysics Data System (ADS)

Wang, Yan; Peng, Zhongyi; Chen, Qun

2018-01-01

To evaluate whether motorized vehicles can travel through a residential area, this paper develops a cellular automata (CA) model to simulate the interactions between pedestrian crossings and motorized vehicles in a residential area. In this paper, pedestrians determine their crossing speed according to their judgments of the position and velocity of the upcoming vehicles. The pedestrians may walk slowly or quickly or even run, and the pedestrian crossing time influences the vehicle movement. In addition, the proposed model considers the safety margin time needed for pedestrians to cross, and pedestrian-vehicle conflict is considered using the vehicle collision avoidance rule. Through simulations of interactions of pedestrian crossings with motorized vehicles' movement on a typical road in a residential area, the average wait time for pedestrians to cross and the average vehicle velocity under different pedestrian crossing volumes, different vehicle flows and different maximum vehicle velocities are obtained. To avoid an excessive waiting time for pedestrians to cross, the vehicle flow should be less than 180 veh/h, which allows an average of less than 10 s of waiting time; if the vehicle flow rate is less than 36 veh/h, then the waiting time is approximately 1 s. Field observations are conducted to validate the simulation results.

Socio-demographic characteristics, lifestyle factors and burden of morbidity associated with self-reported hearing and vision impairments in older British community-dwelling men: a cross-sectional study.

PubMed

Liljas, A E M; Wannamethee, S G; Whincup, P H; Papacosta, O; Walters, K; Iliffe, S; Lennon, L T; Carvalho, L A; Ramsay, S E

2016-06-01

Hearing and vision problems are common in older adults. We investigated the association of self-reported sensory impairment with lifestyle factors, chronic conditions, physical functioning, quality of life and social interaction. A population-based cross-sectional study of participants of the British Regional Heart Study aged 63-85 years. A total of 3981 men (82% response rate) provided data. Twenty-seven per cent (n = 1074) reported hearing impairment including being able to hear with aid (n = 482), being unable to hear (no aid) (n = 424) and being unable to hear despite aid (n = 168). Three per cent (n = 124) reported vision impairment. Not being able to hear, irrespective of use of hearing aid, was associated with poor quality of life, poor social interaction and poor physical functioning. Men who could not hear despite hearing aid were more likely to report coronary heart disease (CHD) [age-adjusted odds ratios (ORs) 1.89 (95% confidence interval 1.36-2.63)]. Vision impairment was associated with symptoms of CHD including breathlessness [OR 2.06 (1.38-3.06)] and chest pain [OR 1.58 (1.07-2.35)]. Vision impairment was also associated with poor quality of life, poor social interaction and poor physical functioning. Sensory impairment is associated with poor physical functioning, poor health and poor social interaction in older men. Further research is warranted on pathways underlying these associations. © The Author 2015. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Pregnancy, prescription medicines and the potential risk of herb-drug interactions: a cross-sectional survey.

PubMed

McLay, James S; Izzati, Naila; Pallivalapila, Abdul R; Shetty, Ashalatha; Pande, Binita; Rore, Craig; Al Hail, Moza; Stewart, Derek

2017-12-19

Pregnant women are routinely prescribed medicines while self-medicating with herbal natural products to treat predominantly pregnancy related conditions. The aim of this study was to assess the potential for herb-drug interactions (HDIs) in pregnant women and to explore possible herb-drug interactions and their potential clinical significance. A cross-sectional survey of women during early pregnancy or immediately postpartum in North-East Scotland. Outcome measures included; Prescription medicines use excluding vitamins and potential HDIs assessed using Natural Medicines Comprehensive Database. The survey was completed by 889 respondents (73% response rate). 45.3% (403) reported the use of at least one prescription medicine, excluding vitamins. Of those taking prescription medicines, 44.9% (181) also reported concurrent use of at least one HNP (Range 1-12). A total of 91 different prescription medicines were reported by respondents using HNPs. Of those taking prescription medicines, 44.9% (181) also reported concurrent use of at least one HNP (Range 1-12). Thirty-four herb-drug interactions were identified in 23 (12.7%) women with the potential to increase the risk of postpartum haemorrhage, alter maternal haemodynamics, and enhance maternal/fetal CNS depression. Almost all were rated as moderate (93.9%), one as a potentially major (ginger and nifedipine) and only one minor (ondansetron and chamomile). Almost half of pregnant women in this study were prescribed medicines excluding vitamins and minerals and almost half of these used HNPs. Potential moderate to severe HDIs were identified in an eighth of the study cohort. Healthcare professionals should be aware that the concurrent use of HNPs and prescription medicines during pregnancy is common and carries potential risks.

Long-Term Social Reintegration Outcomes for Burn Survivors With and Without Peer Support Attendance: A Life Impact Burn Recovery Evaluation (LIBRE) Study.

PubMed

Grieve, Brian; Shapiro, Gabriel D; Wibbenmeyer, Lucy; Acton, Amy; Lee, Austin; Marino, Molly; Jette, Alan; Schneider, Jeffrey C; Kazis, Lewis E; Ryan, Colleen M

2017-10-31

To examine differences in long-term social reintegration outcomes for burn survivors with and without peer support attendance. Cross-sectional survey. Community-dwelling burn survivors. Burn survivors (N=601) aged ≥18 years with injuries to ≥5% total body surface area (TBSA) or burns to critical areas (hands, feet, face, or genitals). Not applicable. The Life Impact Burn Recovery Evaluation Profile was used to examine the following previously validated 6 scale scores of social participation: Family and Friends, Social Interactions, Social Activities, Work and Employment, Romantic Relationships, and Sexual Relationships. Burn support group attendance was reported by 330 (55%) of 596 respondents who responded to this item. Attendees had larger burn size (43.4%±23.6% vs 36.8%±23.4% TBSA burned, P<.01) and were more likely to be >10 years from injury (50% vs 42.5%, P<.01). Survivors who attended at least 1 support group scored significantly higher on 3 of the scales: Social Interactions (P=.01), Social Activities (P=.04), and Work and Employment (P=.05). In adjusted analyses, peer support attendance was associated with increased scores on the Social Interactions scale, increasing scores by 17% of an SD (95% confidence interval, 1%-33%; P=.04). Burn survivors who reported peer support attendance had better social interaction scores than those who did not. This is the first reported association between peer support group attendance and improvements in community reintegration in burn survivors. This cross-sectional study prompts further exploration into the potential benefits of peer support groups on burn recovery with future intervention studies. Copyright © 2017 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

A Temperature-Dependent, Linearly Interpolable, Tabulated Cross Section Library Based on ENDF/B-VI, Release 7.

DOE Office of Scientific and Technical Information (OSTI.GOV)

CULLEN, D. E.

2001-06-13

Version 00 As distributed, the original evaluated data include cross sections represented in the form of a combination of resonance parameters and/or tabulated energy dependent cross sections, nominally at 0 Kelvin temperature. For use in applications, these ENDF/B-VI, Release 7 data were processed into the form of temperature dependent cross sections at eight temperatures between 0 and 2100 Kelvin, in steps of 300 Kelvin. At each temperature the cross sections are tabulated and linearly interpolable in energy. POINT2000 contains all of the evaluations in the ENDF/B-VI general purpose library, which contains evaluations for 324 materials (isotopes or naturally occurring elementalmore » mixtures of isotopes). No special purpose ENDF/B-VI libraries, such as fission products, thermal scattering, photon interaction data are included. The majority of these evaluations are complete, in the sense that they include all cross sections over the energy range 10-5 eV to at least 20 MeV. However, the following are only partial evaluations that either only contain single reactions and no total cross section (Mg24, K41, Ti46, Ti47, Ti48, Ti50 and Ni59), or do not include energy dependent cross sections above the resonance region (Ar40, Mo92, Mo98, Mo100, In115, Sn120, Sn122 and Sn124). The CCC-638/TART96 code package will soon be updated to TART2000, which is recommended for use with these data. Codes within TART2000 can be used to display these data or to run calculations using these data.« less

Communication: Electron ionization of DNA bases.

PubMed

Rahman, M A; Krishnakumar, E

2016-04-28

No reliable experimental data exist for the partial and total electron ionization cross sections for DNA bases, which are very crucial for modeling radiation damage in genetic material of living cell. We have measured a complete set of absolute partial electron ionization cross sections up to 500 eV for DNA bases for the first time by using the relative flow technique. These partial cross sections are summed to obtain total ion cross sections for all the four bases and are compared with the existing theoretical calculations and the only set of measured absolute cross sections. Our measurements clearly resolve the existing discrepancy between the theoretical and experimental results, thereby providing for the first time reliable numbers for partial and total ion cross sections for these molecules. The results on fragmentation analysis of adenine supports the theory of its formation in space.

Inverse design of multicomponent assemblies

NASA Astrophysics Data System (ADS)

Piñeros, William D.; Lindquist, Beth A.; Jadrich, Ryan B.; Truskett, Thomas M.

2018-03-01

Inverse design can be a useful strategy for discovering interactions that drive particles to spontaneously self-assemble into a desired structure. Here, we extend an inverse design methodology—relative entropy optimization—to determine isotropic interactions that promote assembly of targeted multicomponent phases, and we apply this extension to design interactions for a variety of binary crystals ranging from compact triangular and square architectures to highly open structures with dodecagonal and octadecagonal motifs. We compare the resulting optimized (self- and cross) interactions for the binary assemblies to those obtained from optimization of analogous single-component systems. This comparison reveals that self-interactions act as a "primer" to position particles at approximately correct coordination shell distances, while cross interactions act as the "binder" that refines and locks the system into the desired configuration. For simpler binary targets, it is possible to successfully design self-assembling systems while restricting one of these interaction types to be a hard-core-like potential. However, optimization of both self- and cross interaction types appears necessary to design for assembly of more complex or open structures.

Key aromatic/hydrophobic amino acids controlling a cross-amyloid peptide interaction versus amyloid self-assembly.

PubMed

Bakou, Maria; Hille, Kathleen; Kracklauer, Michael; Spanopoulou, Anna; Frost, Christina V; Malideli, Eleni; Yan, Li-Mei; Caporale, Andrea; Zacharias, Martin; Kapurniotu, Aphrodite

2017-09-01

The interaction of the intrinsically disordered polypeptide islet amyloid polypeptide (IAPP), which is associated with type 2 diabetes (T2D), with the Alzheimer's disease amyloid-β (Aβ) peptide modulates their self-assembly into amyloid fibrils and may link the pathogeneses of these two cell-degenerative diseases. However, the molecular determinants of this interaction remain elusive. Using a systematic alanine scan approach, fluorescence spectroscopy, and other biophysical methods, including heterocomplex pulldown assays, far-UV CD spectroscopy, the thioflavin T binding assay, transmission EM, and molecular dynamics simulations, here we identified single aromatic/hydrophobic residues within the amyloid core IAPP region as hot spots or key residues of its cross-interaction with Aβ40(42) peptide. Importantly, we also find that none of these residues in isolation plays a key role in IAPP self-assembly, whereas simultaneous substitution of four aromatic/hydrophobic residues with Ala dramatically impairs both IAPP self-assembly and hetero-assembly with Aβ40(42). Furthermore, our experiments yielded several novel IAPP analogs, whose sequences are highly similar to that of IAPP but have distinct amyloid self- or cross-interaction potentials. The identified similarities and major differences controlling IAPP cross-peptide interaction with Aβ40(42) versus its amyloid self-assembly offer a molecular basis for understanding the underlying mechanisms. We propose that these insights will aid in designing intervention strategies and novel IAPP analogs for the management of type 2 diabetes, Alzheimer's disease, or other diseases related to IAPP dysfunction or cross-amyloid interactions. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

Positron follow-up in liquid water: I. A new Monte Carlo track-structure code.

PubMed

Champion, C; Le Loirec, C

2006-04-07

When biological matter is irradiated by charged particles, a wide variety of interactions occur, which lead to a deep modification of the cellular environment. To understand the fine structure of the microscopic distribution of energy deposits, Monte Carlo event-by-event simulations are particularly suitable. However, the development of these track-structure codes needs accurate interaction cross sections for all the electronic processes: ionization, excitation, positronium formation and even elastic scattering. Under these conditions, we have recently developed a Monte Carlo code for positrons in water, the latter being commonly used to simulate the biological medium. All the processes are studied in detail via theoretical differential and total cross-section calculations performed by using partial wave methods. Comparisons with existing theoretical and experimental data in terms of stopping powers, mean energy transfers and ranges show very good agreements. Moreover, thanks to the theoretical description of positronium formation, we have access, for the first time, to the complete kinematics of the electron capture process. Then, the present Monte Carlo code is able to describe the detailed positronium history, which will provide useful information for medical imaging (like positron emission tomography) where improvements are needed to define with the best accuracy the tumoural volumes.

Measurement of the Total Cross Section of Uranium-Uranium Collisions at √{sNN} = 192 . 8 GeV

NASA Astrophysics Data System (ADS)

Baltz, A. J.; Fischer, W.; Blaskiewicz, M.; Gassner, D.; Drees, K. A.; Luo, Y.; Minty, M.; Thieberger, P.; Wilinski, M.; Pshenichnov, I. A.

2014-03-01

The total cross section of Uranium-Uranium at √{sNN} = 192 . 8 GeV has been measured to be 515 +/-13stat +/-22sys barn, which agrees with the calculated theoretical value of 487.3 barn within experimental error. That this total cross section is more than an order of magnitude larger than the geometric ion-ion cross section is primarily due to Bound-Free Pair Production (BFPP) and Electro-Magnetic Dissociation (EMD). Nearly all beam losses were due to geometric, BFPP and EMD collisions. This allowed the determination of the total cross section from the measured beam loss rates and luminosity. The beam loss rate is calculated from a time-dependent measurement of the total beam intensity. The luminosity is measured via the detection of neutron pairs in time-coincidence in the Zero Degree Calorimeters. Apart from a general interest in verifying the calculations experimentally, an accurate prediction of the losses created in the heavy ion collisions is of practical interest for the LHC, where collision products have the potential to quench cryogenically cooled magnets.

Stratigraphic Architecture of Aeolian Dune Interactions

NASA Astrophysics Data System (ADS)

Brothers, S. C.; Kocurek, G.

2015-12-01

Dune interactions, which consist of collisions and detachments, are a known driver of changing dune morphology and provide the dynamics for field-scale patterning. Although interactions are ubiquitous in modern dune fields, the stratigraphic record of interactions has not been explored. This raises the possibility that an entire class of signature architectures of bounding surfaces and cross-strata has gone misidentified or unrecognized. A unique data set for the crescentic dunes of the White Sands Dune Field, New Mexico, allows for the coupling of dune interactions with their resultant stratigraphic architecture. Dune interactions are documented by a decadal time-series of aerial photos and LiDAR-derived digital elevation models. Plan-view cross-strata in interdune areas provide a record tying past dune positions and morphologies to the current dunes. Three-dimensional stratigraphic architecture is revealed by imaging of dune interiors with ground-penetrating radar. The architecture of a dune defect merging with a target dune downwind consists of lateral truncation of the target dune set by an interaction bounding surface. Defect cross-strata tangentially approach and downlap onto the surface. Downwind, the interaction surface curves, and defect and adjacent target dune sets merge into a continuous set. Predictable angular relationships reflect field-scale patterns of dune migration direction and approach angle of migrating defects. The discovery of interaction architectures emphasizes that although dunes appear as continuous forms on the surface, they consist of discrete segments, each with a distinct morphodynamic history. Bedform interactions result in the morphologic recombination of dune bodies, which is manifested stratigraphically within the sets of cross-strata.

Pathway cross-talk network analysis identifies critical pathways in neonatal sepsis.

PubMed

Meng, Yu-Xiu; Liu, Quan-Hong; Chen, Deng-Hong; Meng, Ying

2017-06-01

Despite advances in neonatal care, sepsis remains a major cause of morbidity and mortality in neonates worldwide. Pathway cross-talk analysis might contribute to the inference of the driving forces in bacterial sepsis and facilitate a better understanding of underlying pathogenesis of neonatal sepsis. This study aimed to explore the critical pathways associated with the progression of neonatal sepsis by the pathway cross-talk analysis. By integrating neonatal transcriptome data with known pathway data and protein-protein interaction data, we systematically uncovered the disease pathway cross-talks and constructed a disease pathway cross-talk network for neonatal sepsis. Then, attract method was employed to explore the dysregulated pathways associated with neonatal sepsis. To determine the critical pathways in neonatal sepsis, rank product (RP) algorithm, centrality analysis and impact factor (IF) were introduced sequentially, which synthetically considered the differential expression of genes and pathways, pathways cross-talks and pathway parameters in the network. The dysregulated pathways with the highest IF values as well as RP<0.01 were defined as critical pathways in neonatal sepsis. By integrating three kinds of data, only 6919 common genes were included to perform the pathway cross-talk analysis. By statistic analysis, a total of 1249 significant pathway cross-talks were selected to construct the pathway cross-talk network. Moreover, 47 dys-regulated pathways were identified via attract method, 20 pathways were identified under RP<0.01, and the top 10 pathways with the highest IF were also screened from the pathway cross-talk network. Among them, we selected 8 common pathways, i.e. critical pathways. In this study, we systematically tracked 8 critical pathways involved in neonatal sepsis by integrating attract method and pathway cross-talk network. These pathways might be responsible for the host response in infection, and of great value for advancing diagnosis and therapy of neonatal sepsis. Copyright © 2017 Elsevier Ltd. All rights reserved.

Gene-diet interaction of a common FADS1 variant with marine polyunsaturated fatty acids for fatty acid composition in plasma and erythrocytes among men.

PubMed

Takkunen, Markus J; de Mello, Vanessa D; Schwab, Ursula S; Kuusisto, Johanna; Vaittinen, Maija; Ågren, Jyrki J; Laakso, Markku; Pihlajamäki, Jussi; Uusitupa, Matti I J

2016-02-01

Limited information exists on how the relationship between dietary intake of fat and fatty acids in erythrocytes and plasma is modulated by polymorphisms in the FADS gene cluster. We examined gene-diet interaction of total marine PUFA intake with a known gene encoding Δ-5 desaturase enzyme (FADS1) variant (rs174550) for fatty acids in erythrocyte membranes and plasma phospholipids (PL), cholesteryl esters (CE), and triglycerides (TG). In this cross-sectional study, fatty acid compositions were measured using GC, and total intake of polyunsaturated fat from fish and fish oil was estimated using a food frequency questionnaire in a subsample (n = 962) of the Metabolic Syndrome in Men Study. We found nominally significant gene-diet interactions for eicosapentaenoic acid (EPA, 20:5n-3) in erythrocytes (pinteraction = 0.032) and for EPA in plasma PL (pinteraction = 0.062), CE (pinteraction = 0.035), and TG (pinteraction = 0.035), as well as for docosapentaenoic acid (22:5n-3) in PL (pinteraction = 0.007). After excluding omega-3 supplement users, we found a significant gene-diet interaction for EPA in erythrocytes (pinteraction < 0.003). In a separate cohort of the Kuopio Obesity Surgery Study, the same locus was strongly associated with hepatic mRNA expression of FADS1 (p = 1.5 × 10(-10) ). FADS1 variants may modulate the relationship between marine fatty acid intake and circulating levels of long-chain omega-3 fatty acids. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Thick-target transmission method for excitation functions of interaction cross sections

NASA Astrophysics Data System (ADS)

Aikawa, M.; Ebata, S.; Imai, S.

2016-09-01

We propose a method, called as thick-target transmission (T3) method, to obtain an excitation function of interaction cross sections. In an ordinal experiment to measure the excitation function of interaction cross sections by the transmission method, we need to change the beam energy for each cross section. In the T3 method, the excitation function is derived from the beam attenuations measured at the targets of different thicknesses without changing the beam energy. The advantage of the T3 method is the simplicity and availability for radioactive beams. To confirm the availability, we perform a simulation for the 12C + 27Al system with the PHITS code instead of actual experiments. Our results have large uncertainties but well reproduce the tendency of the experimental data.

Self-aggregation and coaggregation of the p53 core fragment with its aggregation gatekeeper variant.

PubMed

Lei, Jiangtao; Qi, Ruxi; Wei, Guanghong; Nussinov, Ruth; Ma, Buyong

2016-03-21

Recent studies suggested that p53 aggregation can lead to loss-of-function (LoF), dominant-negative (DN) and gain-of-function (GoF) effects, with adverse cancer consequences. The p53 aggregation-nucleating (251)ILTIITL(257) fragment is a key segment in wild-type p53 aggregation; however, an I254R mutation can prevent it. It was suggested that self-assembly of wild-type p53 and its cross-interaction with mutants differ from the classical amyloid nucleation-growth mechanism. Here, using replica exchange molecular dynamics (REMD) simulations, we studied the cross-interactions of this p53 core fragment and its aggregation rescue I254R mutant. We found that the core fragment displays strong aggregation propensity, whereas the gatekeeper I254R mutant tends to be disordered, consistent with experiments. Our cross-interaction results reveal that the wild-type p53 fragment promotes β-sheet formation of the I254R mutant by shifting the disordered mutant peptides into aggregating states. As a result, the system has similar oligomeric structures, inter-peptide interactions and free energy landscape as the wild type fragment does, revealing a prion-like process. We also found that in the cross-interaction system, the wild-type species has higher tendency to interact with the mutant than with itself. This phenomenon illustrates synergistic effects between the p53 (251)ILTIITL(257) fragment and the mutant resembling prion cross-species propagation, cautioning against exploiting it in drug discovery.

Theoretical study of EAS hadronic structure

NASA Technical Reports Server (NTRS)

Popova, L.

1985-01-01

The structure of extensive air showers (EAS) is determined mainly by the energetic hadrons. They are strongly collimated in the core of the shower and essential difficulties are encountered for resolution of individual hadrons. The properties for resolution are different from the variety of hadron detectors used in EAS experiments. This is the main difficulty in obtaining a general agreement between actually registered data with different detectors. The most plausible source for disagreement is the uncertainty in determination of the energy of individual hadrons. This research demonstrates that a better agreement can be obtained with the average tendency of hadronic measurements if one assumes a larger coefficient of inelasticity and stronger energy increase of the total inelastic cross section in high energy pion interactions. EAS data above 10 to the 5th power GeV are revealing a faster development of hadronic cascades in the air then can be expected by extrapolating the parameters of hadron interactions obtained in accelerator measurements.

Evidence for Neutral-Current Diffractive π 0 Production from Hydrogen in Neutrino Interactions on Hydrocarbon

DOE PAGES

Wolcott, J.; Aliaga, L.; Altinok, O.; ...

2016-09-01

Here, the MINERvA experiment observes an excess of events containing electromagnetic showers relative to the expectation from Monte Carlo simulations in neutral-current neutrino interactions with mean beam energy of 4.5 GeV on a hydrocarbon target. The excess is characterized and found to be consistent with neutral-current π 0 production with a broad energy distribution peaking at 7 GeV and a total cross section of 0.26more » $$\\pm$$ 0.02 (stat) $$\\pm$$ 0.08 (sys) x $$10^{-39} cm^{2}$$. The angular distribution, electromagnetic shower energy, and spatial distribution of the energy depositions of the excess are consistent with expectations from neutrino neutral-current diffractive neutral pion production from hydrogen in the hydrocarbon target. These data comprise the first direct experimental observation and constraint for a reaction that poses an important background process in neutrino oscillation experiments searching for $$\

Resonance production in. gamma gamma. collisions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Renard, F.M.

1983-04-01

The processes ..gamma gamma.. ..-->.. hadrons can be depicted as follows. One photon creates a q anti q pair which starts to evolve; the other photon can either (A) make its own q anti q pair and the (q anti q q anti q) system continue to evolve or (B) interact with the quarks of the first pair and lead to a modified (q anti q) system in interaction with C = +1 quantum numbers. A review of the recent theoretical activity concerning resonance production and related problems is given under the following headings: hadronic C = +1 spectroscopy (qmore » anti q, qq anti q anti q, q anti q g, gg, ggg bound states and mixing effects); exclusive ..gamma gamma.. processes (generalities, unitarized Born method, VDM and QCD); total cross section (soft and hard contributions); q/sup 2/ dependence of soft processes (soft/hard separation, 1/sup +- +/ resonances); and polarization effects. (WHK)« less

Dark Matter Results from First 98.7 Days of Data from the PandaX-II Experiment.

PubMed

Tan, Andi; Xiao, Mengjiao; Cui, Xiangyi; Chen, Xun; Chen, Yunhua; Fang, Deqing; Fu, Changbo; Giboni, Karl; Giuliani, Franco; Gong, Haowei; Guo, Xuyuan; Han, Ke; Hu, Shouyang; Huang, Xingtao; Ji, Xiangdong; Ju, Yonglin; Lei, Siao; Li, Shaoli; Li, Xiaomei; Li, Xinglong; Liang, Hao; Lin, Qing; Liu, Huaxuan; Liu, Jianglai; Lorenzon, Wolfgang; Ma, Yugang; Mao, Yajun; Ni, Kaixuan; Ren, Xiangxiang; Schubnell, Michael; Shen, Manbin; Shi, Fang; Wang, Hongwei; Wang, Jimin; Wang, Meng; Wang, Qiuhong; Wang, Siguang; Wang, Xuming; Wang, Zhou; Wu, Shiyong; Xiao, Xiang; Xie, Pengwei; Yan, Binbin; Yang, Yong; Yue, Jianfeng; Zeng, Xionghui; Zhang, Hongguang; Zhang, Hua; Zhang, Huanqiao; Zhang, Tao; Zhao, Li; Zhou, Jing; Zhou, Ning; Zhou, Xiaopeng

2016-09-16

We report the weakly interacting massive particle (WIMP) dark matter search results using the first physics-run data of the PandaX-II 500 kg liquid xenon dual-phase time-projection chamber, operating at the China JinPing underground laboratory. No dark matter candidate is identified above background. In combination with the data set during the commissioning run, with a total exposure of 3.3×10^{4}  kg day, the most stringent limit to the spin-independent interaction between the ordinary and WIMP dark matter is set for a range of dark matter mass between 5 and 1000  GeV/c^{2}. The best upper limit on the scattering cross section is found 2.5×10^{-46}  cm^{2} for the WIMP mass 40  GeV/c^{2} at 90% confidence level.

Measurement of the inclusive energy spectrum in the very forward direction in proton-proton collisions at $$ \\sqrt{s}=13 $$ TeV

DOE PAGES

Sirunyan, A. M.; Tumasyan, A.; Adam, W.; ...

2017-08-11

The differential cross section for inclusive particle production as a function of energy in proton-proton collisions at a center-of-mass energy of 13 TeV is measured in the very forward region of the CMS detector. The measurement is based on data collected with the CMS apparatus at the LHC, and corresponds to an integrated luminosity of 0.34 μb –1. The energy is measured in the CASTOR calorimeter, which covers the pseudorapidity region -6.6 < η < -5.2. The results are given as a function of the total energy deposited in CASTOR, as well as of its electromagnetic and hadronic components. Furthermore,more » the spectra are sensitive to the modeling of multiparton interactions in pp collisions, and provide new constraints for hadronic interaction models used in collider and in high energy cosmic ray physics.« less

Analysis of Nidogen-1/Laminin γ1 Interaction by Cross-Linking, Mass Spectrometry, and Computational Modeling Reveals Multiple Binding Modes

PubMed Central

Lössl, Philip; Kölbel, Knut; Tänzler, Dirk; Nannemann, David; Ihling, Christian H.; Keller, Manuel V.; Schneider, Marian; Zaucke, Frank; Meiler, Jens; Sinz, Andrea

2014-01-01

We describe the detailed structural investigation of nidogen-1/laminin γ1 complexes using full-length nidogen-1 and a number of laminin γ1 variants. The interactions of nidogen-1 with laminin variants γ1 LEb2–4, γ1 LEb2–4 N836D, γ1 short arm, and γ1 short arm N836D were investigated by applying a combination of (photo-)chemical cross-linking, high-resolution mass spectrometry, and computational modeling. In addition, surface plasmon resonance and ELISA studies were used to determine kinetic constants of the nidogen-1/laminin γ1 interaction. Two complementary cross-linking strategies were pursued to analyze solution structures of laminin γ1 variants and nidogen-1. The majority of distance information was obtained with the homobifunctional amine-reactive cross-linker bis(sulfosuccinimidyl)glutarate. In a second approach, UV-induced cross-linking was performed after incorporation of the diazirine-containing unnatural amino acids photo-leucine and photo-methionine into laminin γ1 LEb2–4, laminin γ1 short arm, and nidogen-1. Our results indicate that Asn-836 within laminin γ1 LEb3 domain is not essential for complex formation. Cross-links between laminin γ1 short arm and nidogen-1 were found in all protein regions, evidencing several additional contact regions apart from the known interaction site. Computational modeling based on the cross-linking constraints indicates the existence of a conformational ensemble of both the individual proteins and the nidogen-1/laminin γ1 complex. This finding implies different modes of interaction resulting in several distinct protein-protein interfaces. PMID:25387007

Improving machine learning reproducibility in genetic association studies with proportional instance cross validation (PICV).

PubMed

Piette, Elizabeth R; Moore, Jason H

2018-01-01

Machine learning methods and conventions are increasingly employed for the analysis of large, complex biomedical data sets, including genome-wide association studies (GWAS). Reproducibility of machine learning analyses of GWAS can be hampered by biological and statistical factors, particularly so for the investigation of non-additive genetic interactions. Application of traditional cross validation to a GWAS data set may result in poor consistency between the training and testing data set splits due to an imbalance of the interaction genotypes relative to the data as a whole. We propose a new cross validation method, proportional instance cross validation (PICV), that preserves the original distribution of an independent variable when splitting the data set into training and testing partitions. We apply PICV to simulated GWAS data with epistatic interactions of varying minor allele frequencies and prevalences and compare performance to that of a traditional cross validation procedure in which individuals are randomly allocated to training and testing partitions. Sensitivity and positive predictive value are significantly improved across all tested scenarios for PICV compared to traditional cross validation. We also apply PICV to GWAS data from a study of primary open-angle glaucoma to investigate a previously-reported interaction, which fails to significantly replicate; PICV however improves the consistency of testing and training results. Application of traditional machine learning procedures to biomedical data may require modifications to better suit intrinsic characteristics of the data, such as the potential for highly imbalanced genotype distributions in the case of epistasis detection. The reproducibility of genetic interaction findings can be improved by considering this variable imbalance in cross validation implementation, such as with PICV. This approach may be extended to problems in other domains in which imbalanced variable distributions are a concern.

α versus non-α cluster decays of the excited compound nucleus *124Ce using various formulations of the nuclear proximity potential

NASA Astrophysics Data System (ADS)

Kaur, Arshdeep; Chopra, Sahila; Gupta, Raj K.

2015-06-01

The earlier study of *124Ce formed in the 32S+92Mo reaction at an above barrier beam energy of 150 MeV, using the pocket formula of Blocki et al. for the nuclear proximity potential in the dynamical cluster-decay model (DCM), is extended to the use of other nuclear interaction potentials derived from the Skyrme energy density functional (SEDF) based on the semiclassical extended Thomas Fermi (ETF) approach under the frozen density approximation. The Skyrme forces used are the old SII, SIII, SIV, SKa, SkM, and SLy4 and new GSkI and KDE0(v1), given for both normal and isospin-rich nuclei. It is found that the α -nucleus structure, over the non-α nucleus structure, is preferred for only two Skyrme forces, the SIII and KDE0(v1). An extended intermediate mass fragments (IMFs) window, along with the new decay region of heavy mass fragments (HMFs) and the near-symmetric and symmetric fission fragments which, on adding the complementary heavy fragments, corresponds to (A /2 )±12 mass region of the fusion-fission (ff) process, are predicted by considering cross sections of orders observed in the experiment under study. For the predicted (total) fusion cross section, the survival probability Psurv of the compound nucleus (CN) against fission is shown to be very small because of the very large predicted ff component. On the other hand, the CN formation probability PCN is found to be nearly equal to 1, and hence the decay under study is a pure CN decay for all the nuclear potentials considered, since the estimated noncompound nucleus (nCN) content is almost negligible. We have also applied the extended-Wong model of Gupta and collaborators, and find that the ℓmax values and total fusion cross sections are of the same order as for the DCM. Thus, the extended-Wong model, which describes only the total fusion cross section in terms of the barrier characteristics of the entrance channel nuclei, could be useful for initial experimental studies to be fully treated using the DCM for all the observed decay products.

X-ray lines and self-interacting dark matter.

PubMed

Mambrini, Yann; Toma, Takashi

We study the correlation between a monochromatic signal from annihilating dark matter and its self-interacting cross section. We apply our argument to a complex scalar dark sector, where the pseudo-scalar plays the role of a warm dark matter candidate while the scalar mediates its interaction with the Standard Model. We combine the recent observation of the cluster Abell 3827 for self-interacting dark matter and the constraints on the annihilation cross section for monochromatic X-ray lines. We also confront our model to a set of recent experimental analyses and find that such an extension can naturally produce a monochromatic keV signal corresponding to recent observations of Perseus or Andromeda, while in the meantime it predicts a self-interacting cross section of the order of [Formula: see text], as recently claimed in the observation of the cluster Abell 3827. We also propose a way to distinguish such models by future direct detection techniques.

Dynamic cross correlation studies of wave particle interactions in ULF phenomena

NASA Technical Reports Server (NTRS)

Mcpherron, R. L.

1979-01-01

Magnetic field observations made by satellites in the earth's magnetic field reveal a wide variety of ULF waves. These waves interact with the ambient particle populations in complex ways, causing modulation of the observed particle fluxes. This modulation is found to be a function of species, pitch angle, energy and time. The characteristics of this modulation provide information concerning the wave mode and interaction process. One important characteristic of wave-particle interactions is the phase of the particle flux modulation relative to the magnetic field variations. To display this phase as a function of time a dynamic cross spectrum program has been developed. The program produces contour maps in the frequency time plane of the cross correlation coefficient between any particle flux time series and the magnetic field vector. This program has been utilized in several studies of ULF wave-particle interactions at synchronous orbit.

Elastic and Inelastic Scattering of 27.6 Mev Deuterons in Ni. Report No. 55; DISPERSION ELASTICA E INELASTICA DE DEUTERONES DE 27,6 Mev POR Ni. INFORME NO. 55

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mayo, S.; Rosenblatt, J.

1961-01-01

Elastic and inelastic differential cross sections in Ni(d,d)Ni with 27.6 Mev deuterons were measured with the aid of scintillation technique. Charged particle spectra from the reaction were observed at laboratory angles of 15 up to 150 degrees, showing the presence of Q-positive stripping protons and elastic and inelastic deuteron groups. Due to isotopic mixture in natural Ni and the rather high level density above 2 Mev of excitation in most of those isotopes, only inelastic deuteron groups going to the first excited states in Ni/sup 58/ and Ni/ sup 60/ could be identified. Elastic angular distribution exhibits similarities to thatmore » obtained by Yntema at 21.6 Mev, showing the typical diffraction patterns. At backward angles, a slight growing in the crosssection was observed which was not observed at 21.6 Mev. By regarding the elastic scattering like a classical light diffraction by a black disk, an interaction radius of 6.8 plus or minus 0.8 f was derived. Inelastic angular distributions were fitted by semiclassical Butler et al. theory and Huby-Newns theory. Due to above-mentioned limitations level mixtures could not be avoided; however, a group of deuterons going to Ni/ sup 58/ 1.45 Mev, probably mixed with Ni/sup 60/ 1.33 Mev, could be identified as proceeding via direct interaction with l = 2 and interaction radius 6.7 f and 6.9 f, respectively. Another inelastic group identified as Ni/sup 58/ 2.46 Mev mixed with Ni/sup 60/ 2.50 Mev is well fitted by l = 2 plus l = 4 and interaction radius 8.9 f and 8.7 f respectively, showing direct interaction behavor. Contributions to the above processes from compound nucleus formation are small as can be seen from absolute cross sections above 50 degrees. Total cross section for the formation of compound nucleus is about 860 mbarn. According to selection rules for deuteron scattering, 2/sup +/ is assigned to levels 1.45 Mev and 2.46 Mev in Ni/sup 58/; however this assignment is not definitive due to background from levels in Ni/sup 58/ and Ni/sup 60/ present at those excitation energies. (auth)« less

The association between betaine and choline intakes and the plasma concentrations of homocysteine in women.

PubMed

Chiuve, Stephanie E; Giovannucci, Edward L; Hankinson, Susan E; Zeisel, Steven H; Dougherty, Lauren W; Willett, Walter C; Rimm, Eric B

2007-10-01

Elevated total homocysteine (tHcy), a risk factor for many chronic diseases, can be remethylated to methionine by folate. Alternatively, tHcy can be metabolized by other 1-carbon nutrients, ie, betaine and its precursor, choline. We aimed to assess the association between the dietary intakes of betaine and choline and the concentration of tHcy. We conducted a cross-sectional analysis in 1477 women by using linear regression models to predict mean fasting tHcy by intakes of of betaine and choline. tHcy was 8% lower in the highest quintile of total betaine + choline intake than in the lowest quintile, even after control for folate intake (P for trend = 0.07). Neither choline nor betaine intake individually was significantly associated with tHcy. Choline from 2 choline-containing compounds, glycerophosphocholine and phosphocholine, was inversely associated with tHcy. These inverse associations were more pronounced in women with folate intake < 400 mug/d than in those with intakes >or=400 microg/d (P for interaction = 0.03 for phosphocholine) and in moderate alcohol drinkers (>or=15 g/d) than in nondrinkers or light drinkers (<15 g/d) (P for interaction = 0.02 for glycerophosphocholine and 0.04 for phosphocholine). The strongest dose response was seen in women with a low-methyl diet (high alcohol and low folate intake) (P for interaction = 0.002 for glycerophosphocholine and 0.001 for phosphocholine). Total choline + betaine intake was inversely associated with tHcy, as was choline from 2 water-soluble choline-containing compounds. Remethylation of tHcy may be more dependent on the betaine pathway when methyl sources are low as a result of either inadequate folate intake or heavier alcohol consumption.

The association between betaine and choline intakes and the plasma concentrations of homocysteine in women2

PubMed Central

Chiuve, Stephanie E; Giovannucci, Edward L; Hankinson, Susan E; Zeisel, Steven H; Dougherty, Lauren W; Willett, Walter C; Rimm, Eric B

2008-01-01

Background Elevated total homocysteine (tHcy), a risk factor for many chronic diseases, can be remethylated to methionine by folate. Alternatively, tHcy can be metabolized by other 1-carbon nutrients, ie, betaine and its precursor, choline. Objective We aimed to assess the association between the dietary intakes of betaine and choline and the concentration of tHcy. Design We conducted a cross-sectional analysis in 1477 women by using linear regression models to predict mean fasting tHcy by intakes of of betaine and choline. Results tHcy was 8% lower in the highest quintile of total betaine + choline intake than in the lowest quintile, even after control for folate intake (P for trend = 0.07). Neither choline nor betaine intake individually was significantly associated with tHcy. Choline from 2 choline-containing compounds, glycerophosphocholine and phosphocholine, was inversely associated with tHcy. These inverse associations were more pronounced in women with folate intake < 400 μg/d than in those with intakes ≥400 μg/d (P for interaction = 0.03 for phosphocholine) and in moderate alcohol drinkers (≥15 g/d) than in nondrinkers or light drinkers (<15 g/d) (P for interaction = 0.02 for glycerophosphocholine and 0.04 for phosphocholine). The strongest dose response was seen in women with a low-methyl diet (high alcohol and low folate intake) (P for interaction = 0.002 for glycerophosphocholine and 0.001 for phosphocholine). Conclusions Total choline + betaine intake was inversely associated with tHcy, as was choline from 2 water-soluble choline-containing compounds. Remethylation of tHcy may be more dependent on the betaine pathway when methyl sources are low as a result of either inadequate folate intake or heavier alcohol consumption. PMID:17921386

Study of BenW (n = 1-12) clusters: An electron collision perspective

NASA Astrophysics Data System (ADS)

Modak, Paresh; Kaur, Jaspreet; Antony, Bobby

2017-08-01

This article explores electron scattering cross sections by Beryllium-Tungsten clusters (BenW). Beryllium and tungsten are important elements for plasma facing wall components, especially for the deuterium/tritium phase of ITER and in the recently installed JET. The present study focuses on different electron impact interactions in terms of elastic cross section (Qel), inelastic cross section (Qinel), ionization cross section (Qion), and momentum transfer cross section (Qmtcs) for the first twelve clusters belonging to the BenW family. It also predicts the evolution of the cross section with the size of the cluster. These cross sections are used as an input to model processes in plasma. The ionization cross section presented here is compared with the available reported data. This is the first comprehensive report on cross section data for all the above-mentioned scattering channels, to the best of our knowledge. Such broad analysis of cross section data gives vital insight into the study of local chemistry of electron interactions with BenW (n = 1-12) clusters in plasma.

Communication: Electron ionization of DNA bases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rahman, M. A.; Krishnakumar, E., E-mail: ekkumar@tifr.res.in

2016-04-28

No reliable experimental data exist for the partial and total electron ionization cross sections for DNA bases, which are very crucial for modeling radiation damage in genetic material of living cell. We have measured a complete set of absolute partial electron ionization cross sections up to 500 eV for DNA bases for the first time by using the relative flow technique. These partial cross sections are summed to obtain total ion cross sections for all the four bases and are compared with the existing theoretical calculations and the only set of measured absolute cross sections. Our measurements clearly resolve themore » existing discrepancy between the theoretical and experimental results, thereby providing for the first time reliable numbers for partial and total ion cross sections for these molecules. The results on fragmentation analysis of adenine supports the theory of its formation in space.« less

Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects

PubMed Central

Sylwester, Andrew W.; Mitchell, Bridget L.; Edgar, John B.; Taormina, Cara; Pelte, Christian; Ruchti, Franziska; Sleath, Paul R.; Grabstein, Kenneth H.; Hosken, Nancy A.; Kern, Florian; Nelson, Jay A.; Picker, Louis J.

2005-01-01

Human cytomegalovirus (HCMV) infections of immunocompetent hosts are characterized by a dynamic, life-long interaction in which host immune responses, particularly of T cells, restrain viral replication and prevent disease but do not eliminate the virus or preclude transmission. Because HCMV is among the largest and most complex of known viruses, the T cell resources committed to maintaining this balance have never been characterized completely. Here, using cytokine flow cytometry and 13,687 overlapping 15mer peptides comprising 213 HCMV open reading frames (ORFs), we found that 151 HCMV ORFs were immunogenic for CD4+ and/or CD8+ T cells, and that ORF immunogenicity was influenced only modestly by ORF expression kinetics and function. We further documented that total HCMV-specific T cell responses in seropositive subjects were enormous, comprising on average ∼10% of both the CD4+ and CD8+ memory compartments in blood, whereas cross-reactive recognition of HCMV proteins in seronegative individuals was limited to CD8+ T cells and was rare. These data provide the first glimpse of the total human T cell response to a complex infectious agent and will provide insight into the rules governing immunodominance and cross-reactivity in complex viral infections of humans. PMID:16147978

Study on Dynamic Strain Aging and Low-Cycle Fatigue of Stainless Steel in Ultra-Supercritical Unit

NASA Astrophysics Data System (ADS)

Hongwei, Zhou; Yizhu, He; Jizu, Lv; Sixian, Rao

Dynamic strain aging (DSA) and low-cycle fatigue (LCF) behavior of TP347H stainless steel in ultra-supercritical unit were investigated at 550-650 °C. All the LCF tests were carried out under a fully-reversed, total axial strain control mode at the total strain amplitude from ±0.2% to ±1.0%. The effects of DSA in cyclic stress response, microstructure evolution and fatigue fracture surfaces and fatigue life were investigated in detail. The results show that DSA occurs during tensile, which is manifested as serrated flow in tensile stress-strain curves. The apparent activation energy for appearing of serrations in tensile stress-strain curves was 270 kJ/mol. Pipe diffusion of substitutional solutes such as Cr and Nb along the dislocation core, and strong interactions between segregated solutes and dislocations are considered as the mechanism of DSA. DSA partly restricts dislocation cross-slip, and dislocation cross-slip and planar-slip happen simultaneously during LCF. A lot of planar structures form, which is due to dislocation gliding on the special plane. This localized deformation structures result in many crack initiation sites. Meanwhile, DSA hardening increases cyclic stress response, accelerating crack propagation, which reduces high temperature strain fatigue life of steel.

Reexamining the role of the (n ,γ f ) process in the low-energy fission of 235U and 239Pu

NASA Astrophysics Data System (ADS)

Lynn, J. E.; Talou, P.; Bouland, O.

2018-06-01

The (n ,γ f ) process is reviewed in light of modern nuclear reaction calculations in both slow and fast neutron-induced fission reactions on 235U and 239Pu. Observed fluctuations of the average prompt fission neutron multiplicity and average total γ -ray energy below 100-eV incident neutron energy are interpreted in this framework. The surprisingly large contribution of the M 1 transitions to the prefission γ -ray spectrum of 239Pu is explained by the dominant fission probabilities of 0+ and 2+ transition states, which can only be accessed from compound nucleus states formed by the interaction of s -wave neutrons with the target nucleus in its ground state, and decaying through M 1 transitions. The impact of an additional low-lying M 1 scissors mode in the photon strength function is analyzed. We review experimental evidence for fission fragment mass and kinetic-energy fluctuations in the resonance region and their importance in the interpretation of experimental data on prompt neutron data in this region. Finally, calculations are extended to the fast energy range where (n ,γ f ) corrections can account for up to 3% of the total fission cross section and about 20% of the capture cross section.

[An ADAA model and its analysis method for agronomic traits based on the double-cross mating design].

PubMed

Xu, Z C; Zhu, J

2000-01-01

According to the double-cross mating design and using principles of Cockerham's general genetic model, a genetic model with additive, dominance and epistatic effects (ADAA model) was proposed for the analysis of agronomic traits. Components of genetic effects were derived for different generations. Monte Carlo simulation was conducted for analyzing the ADAA model and its reduced AD model by using different generations. It was indicated that genetic variance components could be estimated without bias by MINQUE(1) method and genetic effects could be predicted effectively by AUP method; at least three generations (including parent, F1 of single cross and F1 of double-cross) were necessary for analyzing the ADAA model and only two generations (including parent and F1 of double-cross) were enough for the reduced AD model. When epistatic effects were taken into account, a new approach for predicting the heterosis of agronomic traits of double-crosses was given on the basis of unbiased prediction of genotypic merits of parents and their crosses. In addition, genotype x environment interaction effects and interaction heterosis due to G x E interaction were discussed briefly.

Interaction of railway vehicles with track in cross-winds

NASA Astrophysics Data System (ADS)

Xu, Y. L.; Ding, Q. S.

2006-04-01

This paper presents a framework for simulating railway vehicle and track interaction in cross-wind. Each 4-axle vehicle in a train is modeled by a 27-degree-of-freedom dynamic system. Two parallel rails of a track are modeled as two continuous beams supported by a discrete-elastic foundation of three layers with sleepers and ballasts included. The vehicle subsystem and the track subsystem are coupled through contacts between wheels and rails based on contact theory. Vertical and lateral rail irregularities simulated using an inverse Fourier transform are also taken into consideration. The simulation of steady and unsteady aerodynamic forces on a moving railway vehicle in cross-wind is then discussed in the time domain. The Hilber Hughes Taylor α-method is employed to solve the nonlinear equations of motion of coupled vehicle and track systems in cross-wind. The proposed framework is finally applied to a railway vehicle running on a straight track substructure in cross-wind. The safety and comfort performance of the moving vehicle in cross-wind are discussed. The results demonstrate that the proposed framework and the associated computer program can be used to investigate interaction problems of railway vehicles with track in cross-wind.

Organizational justice, psychological distress, and work engagement in Japanese workers.

PubMed

Inoue, Akiomi; Kawakami, Norito; Ishizaki, Masao; Shimazu, Akihito; Tsuchiya, Masao; Tabata, Masaji; Akiyama, Miki; Kitazume, Akiko; Kuroda, Mitsuyo

2010-01-01

To investigate the cross-sectional association between organizational justice (i.e., procedural justice and interactional justice) and psychological distress or work engagement, as well as the mediating roles of other job stressors (i.e., job demands and job control, or their combination, effort-reward imbalance [ERI], and worksite support). A total of 243 workers (185 males and 58 females) from a manufacturing factory in Japan were surveyed using a self-administered questionnaire including the Organizational Justice Questionnaire, Job Content Questionnaire, Effort-Reward Imbalance Questionnaire, K6 scale, Utrecht Work Engagement Scale, and other covariates. Multiple mediation analyses with the bootstrap technique were conducted. In the bivariate analysis, procedural justice and interactional justice were significantly and negatively associated with psychological distress; they were significantly and positively associated with work engagement. In the mediation analysis, reward at work (or ERI) significantly mediated between procedural justice or interactional justice and psychological distress; worksite support significantly mediated between procedural justice or interactional justice and work engagement. The effects of organizational justice on psychological distress seem to be mediated by reward at work (or ERI) while those regarding work engagement may be mediated by worksite support to a large extent, at least in Japanese workers.

European Society of Cardiology Congress 2013 highlights.

PubMed

Fox, Keith A A

2014-01-01

The European Society of Cardiology (ESC) Congress in 2013 met in Amsterdam (The Netherlands) as an innovative and interactive congress involving more than 30,000 participants. There were 10,490 abstract submissions and a total of 227 hotline, basic science hotline and trial update submissions. Participants were involved from more than 150 countries. To make the congress manageable for participants, related topics were grouped together in ‘villages’ and a smart electronic application allowed the participants to guide their way through the congress and choose the sessions of interest. The innovative new program was initiated by the ESC Congress Programme Committee and the Congress Chair (Keith AA Fox, Chair 2012–2014) has responsibility for the design and delivery of the scientific program. The spotlight of the congress was ‘the heart interacting with systemic organs’, chosen because of the importance of cardiovascular disease conditions crossing conventional boundaries. In all 572 abstracts, the work involved an interaction between the heart and another organ, such as the brain, lungs, kidney, vasculature or inflammation system. In addition, innovative new approaches linked basic science and clinical science and the new ‘hubs of the congress’ allowed excellent interaction and exchange of ideas.

The impact of baryonic discs on the shapes and profiles of self-interacting dark matter halos

NASA Astrophysics Data System (ADS)

Sameie, Omid; Creasey, Peter; Yu, Hai-Bo; Sales, Laura V.; Vogelsberger, Mark; Zavala, Jesús

2018-06-01

We employ isolated N-body simulations to study the response of self-interacting dark matter (SIDM) halos in the presence of the baryonic potentials. Dark matter self-interactions lead to kinematic thermalization in the inner halo, resulting in a tight correlation between the dark matter and baryon distributions. A deep baryonic potential shortens the phase of SIDM core expansion and triggers core contraction. This effect can be further enhanced by a large self-scattering cross section. We find the final SIDM density profile is sensitive to the baryonic concentration and the strength of dark matter self-interactions. Assuming a spherical initial halo, we also study evolution of the SIDM halo shape together with the density profile. The halo shape at later epochs deviates from spherical symmetry due to the influence of the non-spherical disc potential, and its significance depends on the baryonic contribution to the total gravitational potential, relative to the dark matter one. In addition, we construct a multi-component model for the Milky Way, including an SIDM halo, a stellar disc and a bulge, and show it is consistent with observations from stellar kinematics and streams.

Solid-phase classical complement activation by C-reactive protein (CRP) is inhibited by fluid-phase CRP-C1q interaction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sjoewall, Christopher; Wetteroe, Jonas; Bengtsson, Torbjoern

2007-01-05

C-reactive protein (CRP) interacts with phosphorylcholine (PC), Fc{gamma} receptors, complement factor C1q and cell nuclear constituents, yet its biological roles are insufficiently understood. The aim was to characterize CRP-induced complement activation by ellipsometry. PC conjugated with keyhole limpet hemocyanin (PC-KLH) was immobilized to cross-linked fibrinogen. A low-CRP serum with different amounts of added CRP was exposed to the PC-surfaces. The total serum protein deposition was quantified and deposition of IgG, C1q, C3c, C4, factor H, and CRP detected with polyclonal antibodies. The binding of serum CRP to PC-KLH dose-dependently triggered activation of the classical pathway. Unexpectedly, the activation was efficientlymore » down-regulated at CRP levels >150 mg/L. Using radial immunodiffusion, CRP-C1q interaction was observed in serum samples with high CRP concentrations. We propose that the underlying mechanism depends on fluid-phase interaction between C1q and CRP. This might constitute another level of complement regulation, which has implications for systemic lupus erythematosus where CRP is often low despite flare-ups.« less

Angular distributions for H- formation in single collisions of H+ on Mg

NASA Astrophysics Data System (ADS)

Alvarez, I.; Cisneros, C.; Russek, A.

1982-07-01

Absolute differential cross sections have been measured for H- formation in single collisions of H+ on Mg in the energy range from 0.5 to 5.0 keV. Total cross sections, obtained by direct integration of these differential cross sections, are in good agreement with earlier total-cross-section measurements of Morgan and Eriksen in the energy range common to the two experiments and are in good agreement with the calculated total cross sections of Olson and Liu. The differential cross sections are strongly peaked in the forward direction. The functional form and scaling properties of this forward peak strongly indicate that it is a glory maximum, which occurs when the classical deflection function changes over from attractive to repulsive at some finite impact parameter. The differential cross sections from 1.0 to 5.0 keV show no other structure, but below 1.0 keV a τ-dependent structure is observed which becomes more pronounced as the collision energy decreases. 1982 The American Physical Society.

The Effect of Acoustic Forcing on Instabilities and Breakdown in Swept-Wing Flow over a Backward-Facing Step

NASA Technical Reports Server (NTRS)

Eppink, Jenna L.; Shishkov, Olga; Wlezien, Richard W.; King, Rudolph A.; Choudhari, Meelan

2016-01-01

Instability interaction and breakdown were experimentally investigated in the flow over a swept backward-facing step. Acoustic forcing was used to excite the Tollmien-Schlichting (TS) instability and to acquire phase-locked results. The phase-averaged results illustrate the complex nature of the interaction between the TS and stationary cross flow instabilities. The weak stationary cross flow disturbance causes a distortion of the TS wavefront. The breakdown process is characterized by large positive and negative spikes in velocity. The positive spikes occur near the same time and location as the positive part of the TS wave. Higher-order spectral analysis was used to further investigate the nonlinear interactions between the TS instability and the traveling cross flow disturbances. The results reveal that a likely cause for the generation of the spikes corresponds to nonlinear interactions between the TS, traveling cross flow, and stationary cross flow disturbances. The spikes begin at low amplitudes of the unsteady and steady disturbances (2-4% U (sub e) (i.e. boundary layer edge velocity)) but can achieve very large amplitudes (20-30 percent U (sub e) (i.e. boundary layer edge velocity)) that initiate an early, though highly intermittent, breakdown to turbulence.

Effect of carbon nanotube dispersion on glass transition in cross-linked epoxy-carbon nanotube nanocomposites: role of interfacial interactions.

PubMed

Khare, Ketan S; Khare, Rajesh

2013-06-20

We have used atomistic molecular simulations to study the effect of nanofiller dispersion on the glass transition behavior of cross-linked epoxy-carbon nanotube (CNT) nanocomposites. Specific chemical interactions at the interface of CNTs and cross-linked epoxy create an interphase region, whose impact on the properties of their nanocomposites increases with an increasing extent of dispersion. To investigate this aspect, we have compared the volumetric, structural, and dynamical properties of three systems: neat cross-linked epoxy, cross-linked epoxy nanocomposite containing dispersed CNTs, and cross-linked epoxy nanocomposite containing aggregated CNTs. We find that the nanocomposite containing dispersed CNTs shows a depression in the glass transition temperature (Tg) by ~66 K as compared to the neat cross-linked epoxy, whereas such a large depression is absent in the nanocomposite containing aggregated CNTs. Our results suggest that the poor interfacial interactions between the CNTs and the cross-linked epoxy matrix lead to a more compressible interphase region between the CNTs and the bulk matrix. An analysis of the resulting dynamic heterogeneity shows that the probability of percolation of immobile domains becomes unity near the Tg calculated from volumetric properties. Our observations also lend support to the conceptual analogy between polymer nanocomposites and the nanoconfinement of polymer thin films.

Microfluidic Synthesis of Composite Cross-Gradient Materials for Investigating Cell–Biomaterial Interactions

PubMed Central

He, Jiankang; Du, Yanan; Guo, Yuqi; Hancock, Matthew J.; Wang, Ben; Shin, Hyeongho; Wu, Jinhui; Li, Dichen; Khademhosseini, Ali

2010-01-01

Combinatorial material synthesis is a powerful approach for creating composite material libraries for the high-throughput screening of cell–material interactions. Although current combinatorial screening platforms have been tremendously successful in identifying target (termed “hit”) materials from composite material libraries, new material synthesis approaches are needed to further optimize the concentrations and blending ratios of the component materials. Here we employed a microfluidic platform to rapidly synthesize composite materials containing cross-gradients of gelatin and chitosan for investigating cell–biomaterial interactions. The microfluidic synthesis of the cross-gradient was optimized experimentally and theoretically to produce quantitatively controllable variations in the concentrations and blending ratios of the two components. The anisotropic chemical compositions of the gelatin/chitosan cross-gradients were characterized by Fourier transform infrared spectrometry and X-ray photoelectron spectrometry. The three-dimensional (3D) porous gelatin/chitosan cross-gradient materials were shown to regulate the cellular morphology and proliferation of smooth muscle cells (SMCs) in a gradient-dependent manner. We envision that our microfluidic cross-gradient platform may accelerate the material development processes involved in a wide range of biomedical applications. PMID:20721897

Total Electron-Impact Ionization Cross-Sections of CFx and NFx (x = 1 - 3)

NASA Technical Reports Server (NTRS)

Huo, Winifred M.; Tarnovsky, Vladimir; Becker, Kurt H.; Kwak, Dochan (Technical Monitor)

2001-01-01

The discrepancy between experimental and theoretical total electron-impact ionization cross sections for a group of fluorides, CFx, and NFx, (x = 1 - 3), is attributed to the inadequacies in previous theoretical models. Cross-sections calculated using a recently developed siBED (simulation Binary-Encounter-Dipole) model that takes into account the shielding of the long-range dipole potential between the scattering electron and target are in agreement with experimentation. The present study also carefully reanalyzed the previously reported experimental data to account for the possibility of incomplete collection of fragment ions and the presence of ion-pair formation channels. For NF3, our experimental and theoretical cross-sections compare well with the total ionization cross-sections recently reported by Haaland et al. in the region below dication formation.

Caregiver stress: does states' expenditure on home- and community-based services matter?

PubMed

Hong, Michin; Casado, Banghwa Lee

2015-01-01

This study examined how state expenditure on home- and community-based services (HCBS) and individual factors are associated with caregiver stress. A total of 1,849 cases from the 2004 National Long-Term Care Survey were included. Gender, education, perceived physical strain, and economic hardship, as well as the number of limitations in instrumental activities of daily living (IADL) for the care recipient, were associated with caregiver stress. The cross-level interaction between service utilization and state expenditure on HCBS was significant, suggesting that living in states with a higher expenditure on HCBS is associated with reduced stress regardless of service utilization.

Electron transfer in proton-hydrogen collisions under dense quantum plasma

NASA Astrophysics Data System (ADS)

Nayek, Sujay; Bhattacharya, Arka; Kamali, Mohd Zahurin Mohamed; Ghoshal, Arijit; Ratnavelu, Kurunathan

2017-09-01

The effects of dense quantum plasma on 1 s → nlm charge transfer, for arbitrary n,l,m, in proton-hydrogen collisions have been studied by employing a distorted wave approximation. The interactions among the charged particles in the plasma have been represented by modified Debye-Huckel potentials. A detailed study has been made to explore the effects of background plasma environment on the differential and total cross sections for electron capture into different angular momentum states for the incident energy in the range 10-1000 keV. For the unscreened case, our results agree well with some of the most accurate results available in the literature.

A new approach to estimate the geometrical factors, solid angle approximation, geometrical efficiency and their use in basic interaction cross section measurements

NASA Astrophysics Data System (ADS)

Rao, D. V.; Cesareo, R.; Brunetti, A.; Gigante, G. E.; Takeda, T.; Itai, Y.; Akatsuka, T.

2002-10-01

A new approach is developed to estimate the geometrical factors, solid angle approximation and geometrical efficiency for a system with experimental arrangements using X-ray tube and secondary target as an excitation source in order to produce the nearly monoenergetic Kα radiation to excite the sample. The variation of the solid angle is studied by changing the radius and length of the collimators towards and away from the source and sample. From these values the variation of the total solid angle and geometrical efficiency is deduced and the optimum value is used for the experimental work.

Serotonin transporter 5-HTTLPR genotype is associated with intrusion and avoidance symptoms of DSM-5 posttraumatic stress disorder (PTSD) in Chinese earthquake survivors.

PubMed

Liu, Luobing; Wang, Li; Cao, Chengqi; Cao, Xing; Zhu, Ye; Liu, Ping; Luo, Shu; Zhang, Jianxin

2018-05-01

Prior studies have found that the serotonin transporter gene-linked polymorphic region (5-HTTLPR) interacts with trauma exposure to increase general risk for Posttraumatic Stress Disorder (PTSD). However, there is little knowledge about the effects of the interaction on distinct symptom clusters of PTSD. This study aimed to investigate the relation between the interaction of 5-HTTLPR and earthquake-related exposures and a contemporary phenotypic model of DSM-5 PTSD symptoms in a traumatised adult sample from China. A cross-sectional design with gene-environment interaction (G × E) approach was adopted. Participants were 1131 survivors who experienced 2008 Wenchuan earthquake. PTSD symptoms were assessed with the PTSD Checklist for DSM-5 (PCL-5). The 5-HTTLPR polymorphism was genotyped with capillary electrophoresis (CE) in ABI 3730xl genetic Analyzer. Although there was no significant interaction between 5-HTTLPR and traumatic exposure on total PTSD symptoms, respondents with the LL genotype of 5-HTTLPR who were highly exposed to the earthquake experienced lower intrusion and avoidance symptoms than those with the S-allele carriers. The findings suggest that the 5-HTTLPR may have an important impact on the development of PTSD and add to the extant knowledge on understanding and treating of posttraumatic psychopathology.

Investigating the relationship among transformational leadership, interpersonal interaction and mentoring functions.

PubMed

Huang, Ching-Yuan; Weng, Rhay-Hung; Chen, Yi-Ting

2016-08-01

This study aims to ascertain the relationship between transformational leadership, interpersonal interaction and mentoring functions among new staff nurses. Mentoring functions could improve the job performance of new nurses, provide them with support and thus reduce their turnover rate. A cross-sectional study was employed. A questionnaire survey was carried out to collect data among a sample of new nurses from three hospitals in Taiwan. After gathering a total of 306 valid surveys, multiple regression analysis was applied to test the hypothesis. Inspirational motivation, idealised influence and individualised consideration had positive correlations with the overall mentoring function, but intellectual stimulation showed a positive association only with career development function. Perceived similarity and interaction frequency also had positive correlations with mentoring functions. When the shift overlap rate exceeded 80%, mentoring function showed a negative result. The transformational leadership of mentors would improve the mentoring functions among new staff nurses. Perceived similarity and interaction frequency between mentees and mentors also had positive correlations with mentoring functions. It is crucial for hospitals to redesign their leadership training and motivation programmes to enhance the transformational leadership of mentors. Furthermore, nursing managers should promote interaction between new staff nurses and their mentors; however, the shift overlap rate should not be too high. © 2016 John Wiley & Sons Ltd.

Being alexithymic: Necessity or convenience. Negative emotionality × avoidant coping interactions and alexithymia.

PubMed

Bilotta, Elena; Giacomantonio, Mauro; Leone, Luigi; Mancini, Francesco; Coriale, Giovanna

2016-09-01

We aimed to clarify the associations between negative emotionality, avoidant coping, and alexithymia. We hypothesized that negative emotionality and avoidance strategies would interact negatively in associating with alexithymia. We examined, in one study conducted in Italy and another in the US (total N = 415), the associations among avoidant coping, negative emotionality, and alexithymia, using cross-sectional designs. Study 1: Participants completed paper-and-pencil measures of alexithymia, avoidant coping, and negative emotionality. Study 2: Participants completed the above-mentioned measures plus a measure of experiential avoidance (EA), by means of an online questionnaire. As expected, an antagonistic avoidant coping × negative emotionality interaction was found to relate to alexithymia in both studies. In Study 2, EA mediated the effects of such interaction on alexithymia (mediated moderation). The interaction found implied that alexithymia would be adopted as a defence against negative affect or as a consequence of avoidant strategies. The studies suggested that two different psychological pathways to alexithymia may be at work: Preference for avoidance and negative emotionality. This result appeared theoretically relevant and may stimulate further research. Alexithymia may develop from habitual avoidance, regardless of negative emotionality. Practitioners could consider addressing negative emotional regulation or automatic and habitual avoidant responses in dealing with alexithymic patients. © 2015 The British Psychological Society.

Introduction to the physics of the total cross section at LHC. A review of data and models

NASA Astrophysics Data System (ADS)

Pancheri, Giulia; Srivastava, Yogendra N.

2017-03-01

This review describes the development of the physics of hadronic cross sections up to recent LHC results and cosmic ray experiments. We present here a comprehensive review - written with a historical perspective - about total cross sections from medium to the highest energies explored experimentally and studied through a variety of methods and theoretical models for over 60 years. We begin by recalling the analytic properties of the elastic amplitude and the theorems about the asymptotic behavior of the total cross section. A discussion of how proton-proton cross sections are extracted from cosmic rays at higher than accelerator energies and help the study of these asymptotic limits, is presented. This is followed by a description of the advent of particle colliders, through which high energies and unmatched experimental precisions have been attained. Thus the measured hadronic elastic and total cross sections have become crucial instruments to probe the so called soft part of QCD physics, where quarks and gluons are confined, and have led to test and refine Regge behavior and a number of diffractive models. As the c.m. energy increases, the total cross section also probes the transition into hard scattering describable with perturbative QCD, the so-called mini-jet region. Further tests are provided by cross section measurements of γ p, γ ^* p and γ ^* γ ^* for models based on vector meson dominance, scaling limits of virtual photons at high Q^2 and the BFKL formalism. Models interpolating from virtual to real photons are also tested.

Positron total scattering cross-sections for alkali atoms

NASA Astrophysics Data System (ADS)

Sinha, Nidhi; Singh, Suvam; Antony, Bobby

2018-01-01

Positron-impact total scattering cross-sections for Li, Na, K, Rb, Cs and Fr atoms are calculated in the energy range from 5-5000 eV employing modified spherical complex optical potential formalism. The main aim of this work is to apply this formalism to the less studied positron-target collision systems. The results are compared with previous theoretical and experimental data, wherever available. In general, the present data show overall agreement and consistency with other results. Furthermore, we have done a comparative study of the results to investigate the effect of atomic size on the cross-sections as we descend through the group in the periodic table. We have also plotted a correlation graph of the present total cross-sections with polarizability and number of target electrons. The two correlation plots confirm the credibility and consistency of the present results. Besides, this is the first theoretical attempt to report positron-impact total cross-sections of alkali atoms over such a wide energy range.

Identity Processes and Parent-Child and Sibling Relationships in Adolescence: A Five-Wave Multi-Informant Longitudinal Study.

PubMed

Crocetti, Elisabetta; Branje, Susan; Rubini, Monica; Koot, Hans M; Meeus, Wim

2017-01-01

The purpose of this study was to examine reciprocal associations between identity processes (commitment, in-depth exploration, and reconsideration of commitment) and dimensions (support, negative interaction, and power) of maternal, paternal, and sibling relationships. A total of 497 Dutch families including 14-years-old adolescents (56.9% males), their fathers, mothers, and siblings, for a total of 1,988 respondents, participated in a five-wave longitudinal study. Cross-lagged analyses indicated that commitment and in-depth exploration predicted improvements in family relationships (unidirectional effects), whereas reconsideration of commitment was predicted by low levels of maternal support and worsened the quality of the paternal relationship (reciprocal effects). These results were not moderated by adolescents' gender and sibling characteristics. Theoretical and practical implications are discussed. © 2016 The Authors. Child Development © 2016 Society for Research in Child Development, Inc.

Assessment of possible failure modes and non-destructive examination of the ITER pre-compression rings

NASA Astrophysics Data System (ADS)

Knaster, J.; Evans, D.; Rajainmaki, H.

2012-06-01

The pre-compression rings (PCRs) for the International Thermonuclear Experimental Reactor (ITER) represent one of the largest and most highly stressed composite structures ever designed for long term operation at 4K. Three rings, each 5m in diameter and 337 × 288 mm in cross-section, will be installed at the top and bottom of the eighteen "D" shaped Toroidal Field (TF) coils to apply a total centripetal load of 70 MN per TF coil. The interaction of the 68 kA conductor current circulating in the coil (for a total of 9.1MA) with the required magnetic field to confine the plasma during operation will result in Lorentz forces that build in-plane and out-of-plane loads. The PCRs are essential to keep the stresses below the acceptable level for the ITER magnets structural materials.

Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent

PubMed Central

Follis, Jack L.; Dashti, Hassan S.; Tanaka, Toshiko; Graff, Mariaelisa; Fretts, Amanda M.; Kilpeläinen, Tuomas O.; Wojczynski, Mary K.; Richardson, Kris; Nalls, Mike A.; Schulz, Christina-Alexandra; Liu, Yongmei; Frazier-Wood, Alexis C.; van Eekelen, Esther; Wang, Carol; de Vries, Paul S.; Mikkilä, Vera; Rohde, Rebecca; Psaty, Bruce M.; Hansen, Torben; Feitosa, Mary F.; Lai, Chao-Qiang; Houston, Denise K.; Ferruci, Luigi; Ericson, Ulrika; Wang, Zhe; de Mutsert, Renée; Oddy, Wendy H.; de Jonge, Ester A. L.; Seppälä, Ilkka; Justice, Anne E.; Lemaitre, Rozenn N.; Sørensen, Thorkild I. A.; Province, Michael A.; Parnell, Laurence D.; Garcia, Melissa E.; Bandinelli, Stefania; Orho-Melander, Marju; Rich, Stephen S.; Rosendaal, Frits R.; Pennell, Craig E.; Kiefte-de Jong, Jessica C.; Kähönen, Mika; Young, Kristin L.; Pedersen, Oluf; Aslibekyan, Stella; Rotter, Jerome I.; Mook-Kanamori, Dennis O.; Zillikens, M. Carola; Raitakari, Olli T.; North, Kari E.; Overvad, Kim; Arnett, Donna K.; Hofman, Albert; Lehtimäki, Terho; Tjønneland, Anne; Uitterlinden, André G.; Rivadeneira, Fernando; Franco, Oscar H.; German, J. Bruce; Siscovick, David S.; Cupples, L. Adrienne; Ordovás, José M.

2017-01-01

Scope Body weight responds variably to the intake of dairy foods. Genetic variation may contribute to inter-individual variability in associations between body weight and dairy consumption. Methods and results A genome-wide interaction study to discover genetic variants that account for variation in BMI in the context of low-fat, high-fat and total dairy intake in cross-sectional analysis was conducted. Data from nine discovery studies (up to 25 513 European descent individuals) were meta-analyzed. Twenty-six genetic variants reached the selected significance threshold (p-interaction<10−7), and six independent variants (LINC01512-rs7751666, PALM2/AKAP2-rs914359, ACTA2-rs1388, PPP1R12A-rs7961195, LINC00333-rs9635058, AC098847.1-rs1791355) were evaluated meta-analytically for replication of interaction in up to 17 675 individuals. Variant rs9635058 (128 kb 3′ of LINC00333) was replicated (p-interaction = 0.004). In the discovery cohorts, rs9635058 interacted with dairy (p-interaction = 7.36 × 10−8) such that each serving of low-fat dairy was associated with 0.225 kg m−2 lower BMI per each additional copy of the effect allele (A). A second genetic variant (ACTA2-rs1388) approached interaction replication significance for low-fat dairy exposure. Conclusion Body weight responses to dairy intake may be modified by genotype, in that greater dairy intake may protect a genetic subgroup from higher body weight. PMID:28941034

Systematics of isotopic production cross sections from interactions of relativistic 40Ca in hydrogen

NASA Astrophysics Data System (ADS)

Chen, C.-X.; Albergo, S.; Caccia, Z.; Costa, S.; Crawford, H. J.; Cronqvist, M.; Engelage, J.; Greiner, L.; Guzik, T. G.; Insolia, A.; Knott, C. N.; Lindstrom, P. J.; McMahon, M.; Mitchell, J. W.; Potenza, R.; Russo, G. V.; Soutoul, A.; Testard, O.; Tull, C. E.; Tuvé, C.; Waddington, C. J.; Webber, W. R.; Wefel, J. P.

1997-09-01

The isotopic production cross sections for 40Ca projectiles at 357, 565, and 763 MeV/nucleon interacting in a liquid hydrogen target have been measured by the Transport Collaboration at the LBL HISS facility. The systematics of these cross sections are studied, and the results indicate that nuclear structure effects are present in the isotope production process during the relativistic collisions. The newly measured cross sections are also compared with those predicted by semiempirical and parametric formulas, but the predictions do not fully describe the systematics such as the energy dependence. The consequences of the cross section systematics in galactic cosmic ray studies are also discussed.

Formaldehyde cross-linking and structural proteomics: Bridging the gap.

PubMed

Srinivasa, Savita; Ding, Xuan; Kast, Juergen

2015-11-01

Proteins are dynamic entities constantly moving and altering their structures based on their functions and interactions inside and outside the cell. Formaldehyde cross-linking combined with mass spectrometry can accurately capture interactions of these rapidly changing biomolecules while maintaining their physiological surroundings. Even with its numerous established uses in biology and compatibility with mass spectrometry, formaldehyde has not yet been applied in structural proteomics. However, formaldehyde cross-linking is moving toward analyzing tertiary structure, which conventional cross-linkers have already accomplished. The purpose of this review is to describe the potential of formaldehyde cross-linking in structural proteomics by highlighting its applications, characteristics and current status in the field. Copyright © 2015 Elsevier Inc. All rights reserved.

Rigor force responses of permeabilized fibres from fast and slow skeletal muscles of aged rats.

PubMed

Plant, D R; Lynch, G S

2001-09-01

1. Ageing is generally associated with a decline in skeletal muscle mass and strength and a slowing of muscle contraction, factors that impact upon the quality of life for the elderly. The mechanisms underlying this age-related muscle weakness have not been fully resolved. The purpose of the present study was to determine whether the decrease in muscle force as a consequence of age could be attributed partly to a decrease in the number of cross-bridges participating during contraction. 2. Given that the rigor force is proportional to the approximate total number of interacting sites between the actin and myosin filaments, we tested the null hypothesis that the rigor force of permeabilized muscle fibres from young and old rats would not be different. 3. Permeabilized fibres from the extensor digitorum longus (fast-twitch; EDL) and soleus (predominantly slow-twitch) muscles of young (6 months of age) and old (27 months of age) male F344 rats were activated in Ca2+-buffered solutions to determine force-pCa characteristics (where pCa = -log(10)[Ca2+]) and then in solutions lacking ATP and Ca2+ to determine rigor force levels. 4. The rigor forces for EDL and soleus muscle fibres were not different between young and old rats, indicating that the approximate total number of cross-bridges that can be formed between filaments did not decline with age. We conclude that the age-related decrease in force output is more likely attributed to a decrease in the force per cross-bridge and/or decreases in the efficiency of excitation-contraction coupling.

The impact of parent-child interaction on brain structures: cross-sectional and longitudinal analyses.

PubMed

Takeuchi, Hikaru; Taki, Yasuyuki; Hashizume, Hiroshi; Asano, Kohei; Asano, Michiko; Sassa, Yuko; Yokota, Susumu; Kotozaki, Yuka; Nouchi, Rui; Kawashima, Ryuta

2015-02-04

There is a vast amount of evidence from psychological studies that the amount of parent-child interaction affects the development of children's verbal skills and knowledge. However, despite the vast amount of literature, brain structural development associated with the amount of parent-child interaction has never been investigated. In the present human study, we used voxel-based morphometry to measure regional gray matter density (rGMD) and examined cross-sectional correlations between the amount of time spent with parents and rGMD among 127 boys and 135 girls. We also assessed correlations between the amount of time spent with parents and longitudinal changes that occurred a few years later among 106 boys and 102 girls. After correcting for confounding factors, we found negative effects of spending time with parents on rGMD in areas in the bilateral superior temporal gyrus (STG) via cross-sectional analyses as well as in the contingent areas of the right STG. We also confirmed positive effects of spending time with parents on the Verbal Comprehension score in cross-sectional and longitudinal analyses. rGMD in partly overlapping or contingent areas of the right STG was negatively correlated with age and the Verbal Comprehension score in cross-sectional analyses. Subsequent analyses revealed verbal parent-child interactions have similar effects on Verbal Comprehension scores and rGMD in the right STG in both cross-sectional and longitudinal analyses. These findings indicate that parent-child interactions affect the right STG, which may be associated with verbal skills. Copyright © 2015 the authors 0270-6474/15/352233-13$15.00/0.

Analysis of respiratory and muscle activity by means of cross information function between ventilatory and myographic signals.

PubMed

Alonso, J F; Mañanas, M A; Hoyer, D; Topor, Z L; Bruce, E N

2004-01-01

Analysis of respiratory muscle activity is a promising technique for the study of pulmonary diseases such as obstructive sleep apnea syndrome (OSAS). Evaluation of interactions between muscles is very useful in order to determine the muscular pattern during an exercise. These interactions have already been assessed by means of different linear techniques like cross-spectrum, magnitude squared coherence or cross-correlation. The aim of this work is to evaluate interactions between respiratory and myographic signals through nonlinear analysis by means of cross mutual information function (CMIF), and finding out what information can be extracted from it. Some parameters are defined and calculated from CMIF between ventilatory and myographic signals of three respiratory muscles. Finally, differences in certain parameters were obtained between OSAS patients and healthy subjects indicating different respiratory muscle couplings.

Resonance charge transfer, transport cross sections, and collision integrals for N(+)(3P)-N(4S0) and O(+)(4S0)-O(3P) interactions

NASA Technical Reports Server (NTRS)

Stallcop, James R.; Partridge, Harry; Levin, Eugene

1991-01-01

N2(+) and O2(+) potential energy curves have been constructed by combining measured data with the results from electronic structure calculations. These potential curves have been employed to determine accurate charge exchange cross sections, transport cross sections, and collision integrals for ground state N(+)-N and O(+)-O interactions. The cross sections have been calculated from a semiclassical approximation to the scattering using a computer code that fits a spline curve through the discrete potential data and incorporates the proper long-range behavior of the interactions forces. The collision integrals are tabulated for a broad range of temperatures 250-100,000 K and are intended to reduce the uncertainty in the values of the transport properties of nonequilibrium air, particularly at high temperatures.

Measurement of Neutrino and Antineutrino Charged-Current Inclusive Cross Sections with the MINERvA Detector

DOE Office of Scientific and Technical Information (OSTI.GOV)

Devan, Joshua D.

2015-01-01

Neutrinos are a nearly massless, neutral particle in the Standard Model that only interact via the weak interaction. Experimental confirmation of neutrino oscillations, in which a neutrino created as a particular type (electron, muon or tau) can be observed as a different type after propagating some distance, earned the 2015 Nobel Prize in Physics. Neutrino oscillation experiments rely on accurate measurements of neutrino interactions with matter, such as that presented here. Neutrinos also provide a unique probe of the nucleus, complementary to electron scattering experiments. This thesis presents a measurement of the charged-current inclusive cross section for muon neutrinos and antineutrinos in the energy range 2 to 50 GeV with the MINERvA detector. MINERvA is a neutrino scattering experiment in the NuMI neutrino beam at Fermilab, near Chicago. A cross section measures the probability of an interaction occurring, measured here as a function of neutrino energy. To extract a cross section from data, the observed rate of interactions is corrected for detector efficiency and divided by the number of scattering nucleons in the target and the flux of neutrinos in the beam. The neutrino flux is determined with the low-more » $$\

Total Cross Sections as a Surrogate for Neutron Capture: An Opportunity to Accurately Constrain (n,γ) Cross Sections for Nuclides Beyond the Reach of Direct Measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koehler, Paul E.

2014-03-05

There are many (n,γ) cross sections of great interest to radiochemical diagnostics and to nuclear astrophysics which are beyond the reach of current measurement techniques, and likely to remain so for the foreseeable future. In contrast, total neutron cross sections currently are feasible for many of these nuclides and provide almost all the information needed to accurately calculate the (n,γ) cross sections via the nuclear statistical model (NSM). I demonstrate this for the case of 151Sm; NSM calculations constrained using average resonance parameters obtained from total cross section measurements made in 1975, are in excellent agreement with recent 151Sm (n,γ)more » measurements across a wide range of energy. Furthermore, I demonstrate through simulations that total cross section measurements can be made at the Manuel Lujan Jr. Neutron Scattering Center at the Los Alamos Neutron Science Center for samples as small as 10μg. Samples of this size should be attainable for many nuclides of interest. Finally, I estimate that over half of the radionuclides identified ~20 years ago as having (n,γ) cross sections of importance to s-process nucleosynthesis studies (24/43) and radiochemical diagnostics (11/19), almost none of which have been measured, can be constrained using this technique.« less

Cross-scale interactions, legacies, and spatial connectivity: integrating time and space to predict post-disturbance response across scales

USDA-ARS?s Scientific Manuscript database

Emergent properties and cross-scale interactions are important in driving landscape-scale dynamics during a disturbance event, such as wildfire. We used these concepts related to changing pattern-process relationships across scales to explain ecological responses following disturbance that resulted ...

Advantages and Disadvantages of Cross Grade Level Collaboration to Improve Collegial Interactions

ERIC Educational Resources Information Center

Johnson, Fidelia

2013-01-01

Researchers have connected student achievement to teacher collaboration; however, there is a paucity of studies conducted on how teachers use identified advantages and disadvantages of cross grade level collaboration to improve collegial interactions to achieve better student performance, professional development, teacher effectiveness, and job…

Spatial Attention and Audiovisual Interactions in Apparent Motion

ERIC Educational Resources Information Center

Sanabria, Daniel; Soto-Faraco, Salvador; Spence, Charles

2007-01-01

In this study, the authors combined the cross-modal dynamic capture task (involving the horizontal apparent movement of visual and auditory stimuli) with spatial cuing in the vertical dimension to investigate the role of spatial attention in cross-modal interactions during motion perception. Spatial attention was manipulated endogenously, either…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Delgado-Acosta, E. G.; Napsuciale, Mauro; Rodriguez, Simon

We develop a second order formalism for massive spin 1/2 fermions based on the projection over Poincare invariant subspaces in the ((1/2),0)+(0,(1/2)) representation of the homogeneous Lorentz group. Using the U(1){sub em} gauge principle we obtain a second order description for the electromagnetic interactions of a spin 1/2 fermion with two free parameters, the gyromagnetic factor g and a parameter {xi} related to odd-parity Lorentz structures. We calculate Compton scattering in this formalism. In the particular case g=2, {xi}=0, and for states with well-defined parity, we recover Dirac results. In general, we find the correct classical limit and a finitemore » value r{sub c}{sup 2} for the forward differential cross section, independent of the photon energy and of the value of the parameters g and {xi}. The differential cross section vanishes at high energies for all g, {xi} except in the forward direction. The total cross section at high energies vanishes only for g=2, {xi}=0. We argue that this formalism is more convenient than Dirac theory in the description of low energy electromagnetic properties of baryons and illustrate the point with the proton case.« less

Nuclear model calculations and their role in space radiation research

NASA Technical Reports Server (NTRS)

Townsend, L. W.; Cucinotta, F. A.; Heilbronn, L. H.

2002-01-01

Proper assessments of spacecraft shielding requirements and concomitant estimates of risk to spacecraft crews from energetic space radiation requires accurate, quantitative methods of characterizing the compositional changes in these radiation fields as they pass through thick absorbers. These quantitative methods are also needed for characterizing accelerator beams used in space radiobiology studies. Because of the impracticality/impossibility of measuring these altered radiation fields inside critical internal body organs of biological test specimens and humans, computational methods rather than direct measurements must be used. Since composition changes in the fields arise from nuclear interaction processes (elastic, inelastic and breakup), knowledge of the appropriate cross sections and spectra must be available. Experiments alone cannot provide the necessary cross section and secondary particle (neutron and charged particle) spectral data because of the large number of nuclear species and wide range of energies involved in space radiation research. Hence, nuclear models are needed. In this paper current methods of predicting total and absorption cross sections and secondary particle (neutrons and ions) yields and spectra for space radiation protection analyses are reviewed. Model shortcomings are discussed and future needs presented. c2002 COSPAR. Published by Elsevier Science Ltd. All right reserved.

HZETRN: Description of a free-space ion and nucleon transport and shielding computer program

NASA Technical Reports Server (NTRS)

Wilson, John W.; Badavi, Francis F.; Cucinotta, Francis A.; Shinn, Judy L.; Badhwar, Gautam D.; Silberberg, R.; Tsao, C. H.; Townsend, Lawrence W.; Tripathi, Ram K.

1995-01-01

The high-charge-and energy (HZE) transport computer program HZETRN is developed to address the problems of free-space radiation transport and shielding. The HZETRN program is intended specifically for the design engineer who is interested in obtaining fast and accurate dosimetric information for the design and construction of space modules and devices. The program is based on a one-dimensional space-marching formulation of the Boltzmann transport equation with a straight-ahead approximation. The effect of the long-range Coulomb force and electron interaction is treated as a continuous slowing-down process. Atomic (electronic) stopping power coefficients with energies above a few A MeV are calculated by using Bethe's theory including Bragg's rule, Ziegler's shell corrections, and effective charge. Nuclear absorption cross sections are obtained from fits to quantum calculations and total cross sections are obtained with a Ramsauer formalism. Nuclear fragmentation cross sections are calculated with a semiempirical abrasion-ablation fragmentation model. The relation of the final computer code to the Boltzmann equation is discussed in the context of simplifying assumptions. A detailed description of the flow of the computer code, input requirements, sample output, and compatibility requirements for non-VAX platforms are provided.

Likelihood of Entanglement when Materials are Dropped Vertically onto a Rotating PTO Knuckle.

PubMed

Schwab, Charles V; Rempe, Isaac J

2017-11-20

Power take-off (PTO) is a common method of transferring power from a tractor to a towed piece of machinery. The PTO is also a well-documented cause of severe and often permanent disabling injuries to farm operators. The physical conditions that cause entanglements are not well established. Several studies have explored the parameters of PTO entanglements as materials have been drawn across a rotating PTO knuckle to test for entanglement probability. The objective of this study was to determine probability of entanglement when materials are dropped vertically onto a PTO knuckle spinning at 540 rpm. A total of 360 randomized trials were conducted with ten replications for each of the six positions (center of yoke, edge of yoke rotating downward, edge of yoke rotating upward, center of cross, edge of cross rotating downward, and edge of cross rotating upward) and six different materials (woven cotton athletic shoe lace, cotton workboot lace, leather workboot lace, cotton twine, denim strip, and Tyvek strip). Not a single entanglement was recorded. Dramatic high-speed video imagery authenticated the material's motion and path as it interacted with the rotating PTO knuckle. Copyright© by the American Society of Agricultural Engineers.

Electromagnetic dissociation of U-238 in heavy-ion collisions at 120 MeV/A

NASA Astrophysics Data System (ADS)

Justice, M. L.

1991-04-01

This thesis describes a measurement of the heavy-ion induced electromagnetic dissociation of a 120 MeV/A U-238 beam incident on five targets: Be-9, Al-27, Cu, Ag, and U. Electromagnetic dissociation at this beam energy is essentially a two step process involving the excitation of a giant resonance followed by particle decay. At 120 MeV/A there is predicted to be a significant contribution of the giant quadrupole resonance to the EMD cross sections. The specific exit channel which was looked at was projectile fission. The two fission fragments were detected in coincidence by an array of solid-state (Delta)E-E detectors, allowing the changes of the fragments to be determined to within (+/-) .5 units. The events were sorted on the basis of the sums of the fragments' charges, acceptance corrections were applied, and total cross sections for the most peripheral events were determined. Electromagnetic fission at the beam energy of this experiment always leads to a true charge sum of 92. Due to the imperfect resolution of the detectors, charge sums of 91 and 93 were included in order to account for all of the electromagnetic fission events. The experimentally observed cross sections are due to nuclear interaction processes as well as electromagnetic processes. Under the conditions of this experiment, the cross sections for the beryllium target are almost entirely due to nuclear processes. The nuclear cross sections for the other four targets were determined by extrapolation from the beryllium data using a geometrical scaling model. After subtraction of the nuclear cross sections, the resulting electromagnetic cross sections are compared to theoretical calculations based on the equivalent photon approximation. Systematic uncertainties are discussed and suggestions for improving the experiment are given.

Kaon pair production in pp, pd and dd collisions at COSY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hartmann, M.; Dzyuba, A.; Keshelashvili, I.

2010-08-05

The near-threshold production of kaon-pairs has been investigated in proton-proton, proton-deuteron and deuteron-deuteron collisions at the Cooler Synchrotron COSY. The excitation function for the pp{yields}ppK{sup +}K{sup -} reaction and the invariant K{sup -}p, K{sup -}pp, and K{sup +}K{sup -} mass distributions indicate the presence of both K{sup -}p and K{sup +}K{sup -} final state interactions. Analogous final-state interactions of antikaons with deuterons has been found in the pp{yields}dK{sup +}K{sup 0}-bar reaction as well as in the pn{yields}dK{sup +}K{sup -} reaction, measured in the quasi-free pd{yields}p{sub sp}dK{sup +}K{sup -} process with a 'spectator' proton (p{sub sp}). The existing COSY data onmore » the pd{yields}{sup 3}HeK{sup +}K{sup -} reaction are not yet sufficient to study the K{sup -3}He and K{sup +}K{sup -} final state interactions. A very small total cross section was found for the dd{yields}{sup 4}HeK{sup +}K{sup -} reaction.« less

Path Dependency and the Politics of Socialized Health Care.

PubMed

Brady, David; Marquardt, Susanne; Gauchat, Gordon; Reynolds, Megan M

2016-06-01

Rich democracies exhibit vast cross-national and historical variation in the socialization of health care. Yet, cross-national analyses remain relatively rare in the health policy literature, and health care remains relatively neglected in the welfare state literature. We analyze pooled time series models of the public share of total health spending for eighteen rich democracies from 1960 to 2010. Building on path dependency theory, we present a strategy for modeling the relationship between the initial 1960 public share and the current public share. We also examine two contrasting accounts for how the 1960 public share interacts with conventional welfare state predictors: the self-reinforcing hypothesis expecting positive feedbacks and the counteracting hypothesis expecting negative feedbacks. We demonstrate that most of the variation from 1960 to 2010 in the public share can be explained by a country's initial value in 1960. This 1960 value has a large significant effect in models of 1961-2010, and including the 1960 value alters the coefficients of conventional welfare state predictors. To investigate the mechanism whereby prior social policy influences public opinion about current social policy, we use the 2006 International Social Survey Programme (ISSP). This analysis confirms that the 1960 values predict individual preferences for government spending on health. Returning to the pooled time series, we demonstrate that the 1960 values interact significantly with several conventional welfare state predictors. Some interactions support the self-reinforcing hypothesis, while others support the counteracting hypothesis. Ultimately, this study illustrates how historical legacies of social policy exert substantial influence on the subsequent politics of social policy. Copyright © 2016 by Duke University Press.

Ab initio study of cross-interface electron-phonon couplings in FeSe thin films on SrTiO 3 and BaTiO 3

DOE PAGES

Wang, Y.; Linscheid, A.; Berlijn, T.; ...

2016-04-22

We study the electron-phonon coupling strength near the interface of monolayer and bilayer FeSe thin films on SrTiO 3 , BaTiO 3 , and oxygen-vacant SrTiO 3 substrates, using ab initio methods. The calculated total electron-phonon coupling strength λ = 0.2 – 0.3 cannot account for the high T c ~ 70 K observed in these systems through the conventional phonon-mediated pairing mechanism. In all of these systems, however, we find that the coupling constant of a polar oxygen branch peaks at q = 0 with negligible coupling elsewhere, while the energy of this mode coincides with the offset energymore » of the replica bands measured recently by angle-resolved photoemission spectroscopy experiments. However, the integrated coupling strength for this mode from our current calculations is still too small to produce the observed high T c , even through the more efficient pairing mechanism provided by the forward scattering. Also, we arrive at the same qualitative conclusion when considering a checkerboard antiferromagnetic configuration in the Fe layer. In light of the experimental observations of the replica band feature and the relatively high T c of FeSe monolayers on polar substrates, our results point towards a cooperative role for the electron-phonon interaction, where the cross-interface interaction acts in conjunction with a purely electronic interaction. Finally, we discuss a few scenarios where the coupling strength obtained here may be enhanced.« less

Electron collisions with phenol: Total, integral, differential, and momentum transfer cross sections and the role of multichannel coupling effects on the elastic channel

DOE Office of Scientific and Technical Information (OSTI.GOV)

Costa, Romarly F. da; Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, 09210-580 Santo André, São Paulo; Oliveira, Eliane M. de

2015-03-14

We report theoretical and experimental total cross sections for electron scattering by phenol (C{sub 6}H{sub 5}OH). The experimental data were obtained with an apparatus based in Madrid and the calculated cross sections with two different methodologies, the independent atom method with screening corrected additivity rule (IAM-SCAR), and the Schwinger multichannel method with pseudopotentials (SMCPP). The SMCPP method in the N{sub open}-channel coupling scheme, at the static-exchange-plus-polarization approximation, is employed to calculate the scattering amplitudes at impact energies ranging from 5.0 eV to 50 eV. We discuss the multichannel coupling effects in the calculated cross sections, in particular how the numbermore » of excited states included in the open-channel space impacts upon the convergence of the elastic cross sections at higher collision energies. The IAM-SCAR approach was also used to obtain the elastic differential cross sections (DCSs) and for correcting the experimental total cross sections for the so-called forward angle scattering effect. We found a very good agreement between our SMCPP theoretical differential, integral, and momentum transfer cross sections and experimental data for benzene (a molecule differing from phenol by replacing a hydrogen atom in benzene with a hydroxyl group). Although some discrepancies were found for lower energies, the agreement between the SMCPP data and the DCSs obtained with the IAM-SCAR method improves, as expected, as the impact energy increases. We also have a good agreement among the present SMCPP calculated total cross section (which includes elastic, 32 inelastic electronic excitation processes and ionization contributions, the latter estimated with the binary-encounter-Bethe model), the IAM-SCAR total cross section, and the experimental data when the latter is corrected for the forward angle scattering effect [Fuss et al., Phys. Rev. A 88, 042702 (2013)].« less

Measurement of the total hadronic cross section in e+e- annihilation below 10.56GeV

NASA Astrophysics Data System (ADS)

Besson, D.; Pedlar, T. K.; Cronin-Hennessy, D.; Gao, K. Y.; Hietala, J.; Klein, T.; Kubota, Y.; Lang, B. W.; Poling, R.; Scott, A. W.; Smith, A.; Zweber, P.; Dobbs, S.; Metreveli, Z.; Seth, K. K.; Tomaradze, A.; Ernst, J.; Ecklund, K. M.; Severini, H.; Dytman, S. A.; Love, W.; Savinov, V.; Aquines, O.; Lopez, A.; Mehrabyan, S.; Mendez, H.; Ramirez, J.; Huang, G. S.; Miller, D. H.; Pavlunin, V.; Sanghi, B.; Shipsey, I. P. J.; Xin, B.; Adams, G. S.; Anderson, M.; Cummings, J. P.; Danko, I.; Hu, D.; Moziak, B.; Napolitano, J.; He, Q.; Insler, J.; Muramatsu, H.; Park, C. S.; Thorndike, E. H.; Yang, F.; Artuso, M.; Blusk, S.; Butt, J.; Li, J.; Menaa, N.; Mountain, R.; Nisar, S.; Randrianarivony, K.; Sia, R.; Skwarnicki, T.; Stone, S.; Wang, J. C.; Zhang, K.; Bonvicini, G.; Cinabro, D.; Dubrovin, M.; Lincoln, A.; Asner, D. M.; Edwards, K. W.; Naik, P.; Briere, R. A.; Ferguson, T.; Tatishvili, G.; Vogel, H.; Watkins, M. E.; Rosner, J. L.; Adam, N. E.; Alexander, J. P.; Berkelman, K.; Cassel, D. G.; Duboscq, J. E.; Ehrlich, R.; Fields, L.; Galik, R. S.; Gibbons, L.; Gray, R.; Gray, S. W.; Hartill, D. L.; Heltsley, B. K.; Hertz, D.; Jones, C. D.; Kandaswamy, J.; Kreinick, D. L.; Kuznetsov, V. E.; Mahlke-Krüger, H.; Mohapatra, D.; Onyisi, P. U. E.; Patterson, J. R.; Peterson, D.; Pivarski, J.; Riley, D.; Ryd, A.; Sadoff, A. J.; Schwarthoff, H.; Shi, X.; Stroiney, S.; Sun, W. M.; Wilksen, T.; Athar, S. B.; Patel, R.; Potlia, V.; Yelton, J.; Rubin, P.; Cawlfield, C.; Eisenstein, B. I.; Karliner, I.; Kim, D.; Lowrey, N.; Selen, M.; White, E. J.; Wiss, J.; Mitchell, R. E.; Shepherd, M. R.

2007-10-01

Using the CLEO III detector, we measure absolute cross sections for e+e-→hadrons at seven center-of-mass energies between 6.964 and 10.538 GeV. The values of R, the ratio of hadronic and muon pair production cross sections, are determined within 2% total root-mean-square uncertainty.

Total photoionization cross sections of atomic oxygen from threshold to 44.3 A

NASA Technical Reports Server (NTRS)

Angel, G. C.; Samson, James A. R.

1988-01-01

Synchrotron radiation was used to obtain the relative photoionization cross section of atomic oxygen for the production of singly charged ions over the 44.3-910.5-A wavelength range. Measurement of the contribution of multiple ionization to the cross sections has made possible the determination of total photoionization cross sections below 250 A. The series of autoionizing resonances leading to the 4P state of the oxygen ion has been observed using an ionization-type experimental procedure for the first time.

Hydrology and water quality of Little Cross Creek, Cumberland County, North Carolina, 1996-98

USGS Publications Warehouse

Giorgino, Mary J.; Middleton, Terry L.

2000-01-01

Little Cross Creek is a small stream located in Cumberland County, North Carolina, in the Sand Hills area of the Coastal Plain Province. From August 1996 through August 1998, the U.S. Geological Survey collected streamflow, water-quality, and time-of-travel data at 10 sites in Little Cross Creek Basin to assess ambient conditions and compute loads of suspended sediment, total nitrogen, total phosphorus, and total organic carbon. Streamflows in the Little Cross Creek Basin responded to climatic factors and to human activities such as water withdrawals and controlled releases from impoundments. Peak streamflows were observed during the passages of Hurricane Fran in September 1996 and Hurricane Josephine in October 1996. Streamflows generally were lowest during the summer and early fall of 1997, reflecting drought conditions associated with a prevailing El Nino. At most sites, average streamflow per unit drainage area, or yield, was higher than yields reported previously for the Sand Hills. High yields may have resulted from unidentified inputs of water to the study basins or from underestimation of the contributing drainage area. Bonnie Doone Lake, Kornbow Lake, Mintz Pond, and Glenville Lake, four impoundments of Little Cross Creek, notably influence hydrology and water quality in the basin. Streamflow records indicate that these impoundments dampen peak stormflows and delay the downstream release of stormwater. Time of travel also is affected by seasonal stratification in the reservoirs. In general, sites downstream from reservoirs have lower concentrations of suspended sediment, turbidity, and total phosphorus than sites upstream from reservoirs or sites that receive stormwater runoff. Few water-quality problems were observed in the Little Cross Creek Basin for the constituents that were sampled. However, fecal coliform bacteria commonly exceeded 200 colonies per 100 milliliters at two of the seven monitored sites during the study. Relatively high concentrations of specific conductance, total phosphorus, and total ammonia plus organic nitrogen were observed in Clark Pond Creek, a tributary to Little Cross Creek. Loads and yields of suspended sediment, total nitrogen, total phosphorus, and total organic carbon were computed for the period from October 1996 through September 1997. The highest suspended-sediment yield (230 tons per square mile per year) occurred upstream from Bonnie Doone Lake, probably because there were no impoundments upstream from this site to intercept sediment. Sediment yields at the remaining Little Cross Creek sites were low relative to yields reported from other urban basins in North Carolina. Downstream from Kornbow Lake, yields of suspended sediment (9.50 tons per square mile per year) and total phosphorus (0.011 ton per square mile per year) were very low. Clark Pond Creek had the highest yields ot total phosphorus (0.081 ton per square mile per year) and total organic carbon (11.5 tons per square mile per year). However, total phosphorus yields at all of the Little Cross Creek sites generally were lower than yields measured in other urban basins in the State. Comparison of inflow and outflow loads for the four Little Cross Creek reservoirs from October 1996 through September 1997 indicated that Bonnie Doone Lake trapped 92 percent of incoming sediment and 37 percent of incoming total phosphorus. Kornbow Lake trapped 57 percent of incoming sediment and 77 percent of total phosphorus inputs. Nitrogen was not effectively trapped by any of the reservoirs. An influx of sediment, total phosphorus, and total organic carbon was noted at a site downstream from Mintz Pond, and may have resulted from stormwater discharge from the U.S. Highway 401 bypass or from additional, unidentified sources in the watershed downstream from Kornbow Lake.

Trends and variation in prescribing of low-priority treatments identified by NHS England: a cross-sectional study and interactive data tool in English primary care.

PubMed

Walker, Alex J; Curtis, Helen J; Bacon, Seb; Croker, Richard; Goldacre, Ben

2018-06-01

Objectives NHS England recently announced a consultation seeking to discourage the use of treatments it considers to be low-value. We set out to produce an interactive data resource to show savings in each NHS general practice and to assess the current use of these treatments, their change in use over time, and the extent and reasons for variation in such prescribing. Design Cross-sectional analysis. Setting English primary care. Participants English general practices. Main outcome measures We determined the cost per 1000 patients for prescribing of each of 18 treatments identified by NHS England for each month from July 2012 to June 2017, and also aggregated over the most recent year to assess total cost and variation among practices. We used mixed effects linear regression to determine factors associated with cost of prescribing. Results Spend on low-value treatments was £153.5 m in the last year, across 5.8 m prescriptions (mean, £26 per prescription). Among individual treatments, liothyronine had the highest prescribing cost at £29.6 m, followed by trimipramine (£20.2 m). Over time, the overall total number of low-value prescriptions decreased, but the cost increased, although this varied greatly between treatments. Three treatment areas increased in cost and two increased in volume, all others reduced in cost and volume. Annual practice level spending varied widely (median, £2262 per thousand patients; interquartile range £1439 to £3298). Proportion of patients over 65 was strongly associated with low-value prescribing, as was Clinical Commissioning Group. Our interactive data tool was deployed to OpenPrescribing.net where monthly updated figures and graphs can be viewed. Conclusions Prescribing of low-value treatments is extensive but varies widely by treatment, geographic area and individual practice. Despite a fall in prescription numbers, the overall cost of prescribing for low-value items has risen. Prescribing behaviour is clustered by Clinical Commissioning Group, which may represent variation in the optimisation efficiency of medicines, or in some cases access inequality.

Energy dependence of radiation interaction parameters of some organic compounds

NASA Astrophysics Data System (ADS)

Singh, Mohinder; Tondon, Akash; Sandhu, B. S.; Singh, Bhajan

2018-04-01

Gamma rays interact with a material through photoelectric absorption, Compton scattering, Rayleigh scattering and Pair production in the intermediate energy range. The probability of occurrence of a particular type of process depends on the energy of incident gamma rays, atomic number of the material, scattering angle and geometrical conditions. Various radiological parameters for organic compounds, namely ethylene glycol (C2H6O2), propylene glycol (C3H8O2), glycerin (C3H8O3), isoamyl alcohol (C5H12O), butanone (C4H8O), acetophenone (C8H8O2), cyclohexanone (C6H10O), furfural (C5H4O2), benzaldehyde (C7H6O), cinnamaldehyde (C9H8O), glutaraldehyde (C5H8O2), aniline (C6H7N), benzyl amine (C6H7N), nitrobenzene (C6H5NO2), ethyl benzene (C8H10), ethyl formate (C3H6O2) and water (H2O) are presented at 81, 122, 356 and 511 keV energies employing NaI(Tl) scintillation detector in narrow-beam transmission geometry. The radiation interaction parameters such as mass attenuation, molar extinction and mass energy absorption coefficients, half value layer, total atomic and effective electronic cross-sections and CT number have been evaluated for these organic compounds. The general trend of values of mass attenuation coefficients, half value layer, molar extinction coefficients, total atomic and effective electronic cross-sections and mass energy absorption coefficients shows a decrease with increase in incident gamma photon energy. The values of CT number are found to increases linearly with increase of effective atomic number (Zeff). The variation in CT number around Zeff ≈ 3.3 shows the peak like structure with respect to water and the correlation between CT number and linear attenuation coefficient is about 0.99. Appropriate equations are fitted to these experimentally determined parameters for the organic compounds at incident photon energy ranging from 81 keV to 511 keV used in the present study. Experimental values are compared with the theoretical data obtained using WinXcom software package, and are found in good agreement.

Electron-Impact Total Ionization Cross Sections of CH and C2H2

PubMed Central

Kim, Yong-Ki; Ali, M. Asgar; Rudd, M. Eugene

1997-01-01

Electron-impact total ionization cross sections for the CH radical and C2H2 (acetylene) have been calculated using the Binary-Encounter-Bethe (BEB) model. The BEB model combines the Mott cross section and the asymptotic form of the Bethe theory, and has been shown to generate reliable ionization cross sections for a large variety of molecules. The BEB cross sections for CH and C2H2 are in good agreement with the available experimental data from ionization thresholds to hundreds of eV in incident energies. PMID:27805116

Investigation of the reaction 74Ge(p,γ)75As using the in-beam method to improve reaction network predictions for p nuclei

NASA Astrophysics Data System (ADS)

Sauerwein, A.; Endres, J.; Netterdon, L.; Zilges, A.; Foteinou, V.; Provatas, G.; Konstantinopoulos, T.; Axiotis, M.; Ashley, S. F.; Harissopulos, S.; Rauscher, T.

2012-09-01

Background: Astrophysical models studying the origin of the neutron-deficient p nuclides require knowledge of proton capture cross sections at low energy. The production site of the p nuclei is still under discussion but a firm basis of nuclear reaction rates is required to address the astrophysical uncertainties. Data at astrophysically relevant interaction energies are scarce. Problems with the prediction of charged particle capture cross sections at low energy were found in the comparisons between previous data and calculations in the Hauser-Feshbach statistical model of compound reactions.Purpose: A measurement of 74Ge(p,γ)75As at low proton energies, inside the astrophysically relevant energy region, is important in several respects. The reaction is directly important because it is a bottleneck in the reaction flow which produces the lightest p nucleus 74Se. It is also an important addition to the data set required to test reaction-rate predictions and to allow an improvement in the global p+nucleus optical potential required in such calculations.Method: An in-beam experiment was performed, making it possible to measure in the range 2.1≤Ep≤3.7MeV, which is for the most part inside the astrophysically relevant energy window. Angular distributions of the γ-ray transitions were measured with high-purity germanium detectors at eight angles relative to the beam axis. In addition to the total cross sections, partial cross sections for the direct population of 12 levels were determined.Results: The resulting cross sections were compared to Hauser-Feshbach calculations using the code smaragd. Only a constant renormalization factor of the calculated proton widths allowed a good reproduction of both total and partial cross sections. The accuracy of the calculation made it possible to check the spin assignment of some states in 75As. In the case of the 1075-keV state, a double state with spins and parities of 3/2- and 5/2- is needed to explain the experimental partial cross sections. A change in parity from 5/2+ to 5/2- is required for the state at 401 keV. Furthermore, in the case of 74Ge, studying the combination of total and partial cross sections made it possible to test the γ width, which is essential in the calculation of the astrophysical 74As(n,γ)75As rate.Conclusions: Between data and statistical model prediction a factor of about two was found. Nevertheless, the improved astrophysical reaction rate of 74Ge(p,γ) (and its reverse reaction) is only 28% larger than the previous standard rate. The prediction of the 74As(n,γ)75As rate (and its reverse) was confirmed, the newly calculated rate differs only by a few percent from the previous prediction. The in-beam method with high-efficiency detectors proved to be a powerful tool for studies in nuclear astrophysics and nuclear structure.

Unfavourable family characteristics and their associations with childhood obesity: a cross-sectional study.

PubMed

Moens, Ellen; Braet, Caroline; Bosmans, Guy; Rosseel, Yves

2009-07-01

This cross-sectional study explores the influence of multiple familial factors on children's weight status and the interaction between parenting stress and unfavourable family characteristics. A total of 197 families with children between 6 and 14 years participated in this study. Of this group, 97 families had a child with normal weight and 100 families had a child with overweight. Parents reported on seven family factors (maternal BMI, number of children, family structure, socioeconomic position, life events, parental psychopathology and parenting stress). Families with overweight children experience more parenting stress. A regression analysis revealed that familial factors explain 27% in the variance in child's weight status. The hypothesis that a combination of familial factors will be more able to explain child's adiposity could not be confirmed. Familial factors have moderate ability to predict children's weight status. There is a need to identify other familial mechanisms taking into account developmental and temporal evolutions over the past decade. 2009 John Wiley & Sons, Ltd and Eating Disorders Association

First results from the NEWS-G direct dark matter search experiment at the LSM

NASA Astrophysics Data System (ADS)

Arnaud, Q.; Asner, D.; Bard, J.-P.; Brossard, A.; Cai, B.; Chapellier, M.; Clark, M.; Corcoran, E. C.; Dandl, T.; Dastgheibi-Fard, A.; Dering, K.; Di Stefano, P.; Durnford, D.; Gerbier, G.; Giomataris, I.; Gorel, P.; Gros, M.; Guillaudin, O.; Hoppe, E. W.; Kamaha, A.; Katsioulas, I.; Kelly, D. G.; Martin, R. D.; McDonald, J.; Muraz, J.-F.; Mols, J.-P.; Navick, X.-F.; Papaevangelou, T.; Piquemal, F.; Roth, S.; Santos, D.; Savvidis, I.; Ulrich, A.; Vazquez de Sola Fernandez, F.; Zampaolo, M.

2018-01-01

New Experiments With Spheres-Gas (NEWS-G) is a direct dark matter detection experiment using Spherical Proportional Counters (SPCs) with light noble gases to search for low-mass Weakly Interacting Massive Particles (WIMPs). We report the results from the first physics run taken at the Laboratoire Souterrain de Modane (LSM) with SEDINE, a 60 cm diameter prototype SPC operated with a mixture of Ne + CH4 (0.7%) at 3.1 bars for a total exposure of 9.6 kg · days. New constraints are set on the spin-independent WIMP-nucleon scattering cross-section in the sub-GeV/c2 mass region. We exclude cross-sections above 4.4 ×10-37cm2 at 90% confidence level (C.L.) for a 0.5 GeV/c2 WIMP. The competitive results obtained with SEDINE are promising for the next phase of the NEWS-G experiment: a 140 cm diameter SPC to be installed at SNOLAB by summer 2018.

Photoproduction of lepton pairs in proton-nucleus and nucleus-nucleus collisions at RHIC and LHC energies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moreira, B. D.; Goncalves, V. P.; De Santana Amaral, J. T.

2013-03-25

In this contribution we study coherent interactions as a probe of the nonlinear effects in the Quantum Electrodynamics (QED). In particular, we study the multiphoton effects in the production of leptons pairs for proton-nucleus and nucleus-nucleus collisions for heavy nuclei. In the proton-nucleus we assume the ultrarelativistic proton as a source of photons and estimate the photoproduction of lepton pairs on nuclei at RHIC and LHC energies considering the multiphoton effects associated to multiple rescattering of the projectile photon on the proton of the nucleus. In nucleus - nucleus colllisions we consider the two nuclei as a source of photons.more » As each scattering contributes with a factor {alpha}Z to the cross section, this contribution must be taken into account for heavy nuclei. We consider the Coulomb corrections to calculate themultiple scatterings and estimate the total cross section for muon and tau pair production in proton-nucleus and nucleus-nucleus collisions at RHIC and LHC energies.« less

Widespread Gene Conversion in Centromere Cores

PubMed Central

Shi, Jinghua; Wolf, Sarah E.; Burke, John M.; Presting, Gernot G.; Ross-Ibarra, Jeffrey; Dawe, R. Kelly

2010-01-01

Centromeres are the most dynamic regions of the genome, yet they are typified by little or no crossing over, making it difficult to explain the origin of this diversity. To address this question, we developed a novel CENH3 ChIP display method that maps kinetochore footprints over transposon-rich areas of centromere cores. A high level of polymorphism made it possible to map a total of 238 within-centromere markers using maize recombinant inbred lines. Over half of the markers were shown to interact directly with kinetochores (CENH3) by chromatin immunoprecipitation. Although classical crossing over is fully suppressed across CENH3 domains, two gene conversion events (i.e., non-crossover marker exchanges) were identified in a mapping population. A population genetic analysis of 53 diverse inbreds suggests that historical gene conversion is widespread in maize centromeres, occurring at a rate >1×10−5/marker/generation. We conclude that gene conversion accelerates centromere evolution by facilitating sequence exchange among chromosomes. PMID:20231874

Using Amphiphilic Copolymers and Nanoparticles to Organize Charged Biopolymers

NASA Astrophysics Data System (ADS)

Park, Jung Hyun; McConnell, Marla; Sun, Yujie; Goldman, Yale; Composto, Russell

2009-03-01

Nanoparticles (NPs) on amphiphilic random copolymers control filamentous actin (F-actin) attachment. 3-aminopropyltriethoxysilane (APTES) coated silica NPs are selectively bonded to acrylic acid groups on the surface of a poly(styrene-r-acrylic acid) (PS-r-PAA) film. By changing the concentration of NPs in the medium, the surface density of positively charged anchors is tuned. Using total internal reflection fluorescence (TIRF) microscopy, immobilization of F-actin is observed via electrostatic interaction with NPs at high NP coverages. Below a critical coverage, F-actin is weakly attached and undergoes thermal fluctuations near the surface. Another method to tune F-actin attachment is to use APTES to cross-link and create positive charge in PAA films. Here, the surface coverage of F-actin decreases as APTES concentration increases. This observation is attributed to an increase in surface roughness and hydrophobicity that reduces the effective surface sites that attract F-actin. In addition, in-situ G-actin polymerization to F-actin is observed on both the NP and cross-linked PAA templates.

Industrial ion source technology

NASA Technical Reports Server (NTRS)

Kaufman, H. R.; Robinson, R. S.

1978-01-01

An analytical model was developed to describe the development of a coned surface texture with ion bombardment and simultaneous deposition of an impurity. A mathematical model of sputter deposition rate from a beveled target was developed in conjuction with the texturing models to provide an important input to that model. The establishment of a general procedure that will allow the treatment of manay different sputtering configurations is outlined. Calculation of cross sections for energetic binary collisions was extened to Ar, Kr.. and Xe with total cross sections for viscosity and diffusion calculated for the interaction energy range from leV to 1000eV. Physical sputtering and reactive ion etching experiments provided experimental data on the operating limits of a broad beam ion source using CF4 as a working gas to produce reactive species in a sputtering beam. Magnetic clustering effects are observed when Al is seeded with Fe and sputtered with Ar(?) ions. Silicon was textured at a micron scale by using a substrate temperature of 600 C.

Comparative evaluation of the drug interaction screening programs MediQ and ID PHARMA CHECK in neurological inpatients.

PubMed

Zorina, Olesya I; Haueis, Patrick; Semmler, Alexander; Marti, Isabelle; Gonzenbach, Roman R; Guzek, Markus; Kullak-Ublick, Gerd A; Weller, Michael; Russmann, Stefan

2012-08-01

The comparative evaluation of clinical decision support software (CDSS) programs regarding their sensitivity and positive predictive value for the identification of clinically relevant drug interactions. In this research, we used a cross-sectional study that identified potential drug interactions using the CDSS MediQ and the ID PHARMA CHECK in 484 neurological inpatients. Interactions were reclassified according to the Zurich Interaction System, a multidimensional classification that incorporates the Operational Classification of Drug Interactions. In 484 patients with 2812 prescriptions, MediQ and ID PHARMA CHECK generated a total of 1759 and 1082 alerts, respectively. MediQ identified 658 unique potentially interacting combinations, 8 classified as "high danger," 164 as "average danger," and 486 as "low danger." ID PHARMA CHECK detected 336 combinations assigned to one or several of 12 risk and management categories. Altogether, both CDSS issued alerts relating to 808 unique potentially interacting combinations. According to the Zurich Interaction System, 6 of these were contraindicated, 25 were provisionally contraindicated, 190 carried a conditional risk, and 587 had a minimal risk of adverse events. The positive predictive value for alerts having at least a conditional risk was 0.24 for MediQ and 0.48 for ID PHARMA CHECK. CDSS showed major differences in the identification and grading of interactions, and many interactions were only identified by one of the two CDSS. For both programs, only a small proportion of all identified interactions appeared clinically relevant, and the selected display of alerts that imply management changes is a key issue in the further development and local setup of such programs. Copyright © 2012 John Wiley & Sons, Ltd.

Total leisure noise exposure and its association with hearing loss among adolescents.

PubMed

Dehnert, Knut; Raab, Ulla; Perez-Alvarez, Carmelo; Steffens, Thomas; Bolte, Gabriele; Fromme, Hermann; Twardella, Dorothee

2015-01-01

To investigate total leisure noise exposure among adolescents and to assess its association with hearing. Based on self-reported time spent on 19 leisure activities and associated mean sound pressure levels reported in the literature, total leisure noise exposure was evaluated and compared to noise at work limits (> 85 dB(A) = hazardous) in a cross-sectional survey. Tympanometry and pure-tone audiometry was performed in sound isolated rooms. The study sample consists of 2143 pupils attending grade nine in any school in a German city 2009-2011 (mean age: 15.4 years; range: 13-19 years). Audiometric data were available for 1837 (85.8%) pupils (53.9% girls). 41.9% of the 2143 adolescents who had provided self-reported data on leisure activities associated with noise exposure were estimated to be hazardously exposed to leisure time noise. The interaction of gender with total leisure time noise exposure was not significant. No association between leisure time noise exposure and audiometric notches could be detected. While hearing loss seems seldom in this age group, a high proportion of adolescents aged 15-16 years are exposed to noise levels during leisure time bearing long-term risks of hearing loss.

Single crystal to polycrystal neutron transmission simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dessieux, Luc Lucius; Stoica, Alexandru Dan; Bingham, Philip R.

A collection of routines for calculation of the total cross section that determines the attenuation of neutrons by crystalline solids is presented. The total cross section is calculated semi-empirically as a function of crystal structure, neutron energy, temperature, and crystal orientation. The semi-empirical formula includes the contribution of parasitic Bragg scattering to the total cross section using both the crystal’s mosaic spread value and its orientation with respect to the neutron beam direction as parameters. These routines allow users to enter a distribution of crystal orientations for calculation of total cross sections of user defined powder or pseudo powder distributions,more » which enables simulation of non-uniformities such as texture and strain. In conclusion, the spectra for neutron transmission simulations in the neutron thermal energy range (2 meV–100 meV) are presented for single crystal and polycrystal samples and compared to measurements.« less

Single crystal to polycrystal neutron transmission simulation

DOE PAGES

Dessieux, Luc Lucius; Stoica, Alexandru Dan; Bingham, Philip R.

2018-02-02

A collection of routines for calculation of the total cross section that determines the attenuation of neutrons by crystalline solids is presented. The total cross section is calculated semi-empirically as a function of crystal structure, neutron energy, temperature, and crystal orientation. The semi-empirical formula includes the contribution of parasitic Bragg scattering to the total cross section using both the crystal’s mosaic spread value and its orientation with respect to the neutron beam direction as parameters. These routines allow users to enter a distribution of crystal orientations for calculation of total cross sections of user defined powder or pseudo powder distributions,more » which enables simulation of non-uniformities such as texture and strain. In conclusion, the spectra for neutron transmission simulations in the neutron thermal energy range (2 meV–100 meV) are presented for single crystal and polycrystal samples and compared to measurements.« less

A sub-GeV charged-current quasi-elastic $$\

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walding, Joseph James

2009-12-01

Neutrino-nucleus charged-current quasi-elastic scattering is the signal interaction used by many neutrino oscillation experiments. For muon disappearance studies the signal mode is ν μn → μp. Modern oscillation experiments, such as T2K, produce neutrino beams with peak beam energies of order a few-GeV. It is therefore vitally important to have accurate measurements of the charged-current quasi-elastic crosssection for future neutrino oscillation experiments. Neutrino-nucleus cross-sections in the few-GeV region are not well understood, with the main uncertainties coming from understanding of the neutrino beam flux and the final state interactions within nuclei. SciBooNE is a sub-GeV neutrino-nucleus cross-section experiment based atmore » Fermilab, Batavia, USA, with the goal to measure neutrino cross-sections with precision of order 5%. SciBooNE took data from June 2007 until August 2008, in total 0.99×10 20 and 1.53×10 20 protons on target were collected in neutrino and anti-neutrino mode, respectively. In this thesis a ν μ charged-current quasi-elastic (CCQE) cross-section contained within the SciBar sub-detector is presented. A method to tag muons in SciBar was developed and three samples were isolated. An excess in backwards tracks in the one-track sample is observed. A Poisson maximum likelihood is used to extract the CCQE cross-section. The fit was applied using a basic fit parameter model, successfully used to obtain the cross-section in the SciBar-MRD matched CCQE analysis. This method was found to be insufficient in describing the data for the SciBarcontained CCQE analysis. By adding two migration parameters the cross-section was calculated to be 1.004 ± 0.031 (stat) +0.101 -0.150(sys) × 10 -38 cm 2/neutron, excluding backwards tracks with a χ 2 = 203.8/76 d.o.f. and 1.083 ± 0.030(stat) +0.115 -0.177(sys) × 10 -38 cm 2/neutron, including backwards tracks with a χ 2 = 659.8/133 d.o.f. Only neutrino beam and detector systematics have been considered. Further study of the SciBar-contained sample is suggested, introducing additional fit parameters and considering the remaining systematics. The end goal is to extract a SciBooNE CCQE cross-section using the SciBar-contained and SciBar-MRD matched samples.« less

Long bone robustness during growth: A cross-sectional pQCT examination of children and young adults aged 5-29years.

PubMed

Rantalainen, Timo; Weeks, Benjamin K; Nogueira, Rossana C; Beck, Belinda R

2016-12-01

Skeletal robustness (cross-section size relative to length) is associated with stress fractures in adults, and appears to explain the high incidence of distal radius fractures in adolescents. However, little is known about the ontogeny of long bone robustness during the first three decades of life. Therefore, we explored the ontogeny of tibial, fibular, ulnar and radial robustness in a cross-sectional sample of 5 to 29year-old volunteers of both sexes. Peripheral quantitative computed tomography (pQCT) was used to evaluate cross-sections of the leg (4%, 14%, 38% and 66%), and forearm (4%, and 66%) in N=432 individuals. Robustness was evaluated as the total bone area divided by bone length. Differences between age-groups, sexes, and age-group×sex interactions were evaluated with ANOVA with Tukey's post hocs where appropriate. Most bone sites exhibited more robust bones in men than women (P<0.001 to 0.02), and in older age-groups than younger (P<0.001). Sex×age-group interaction was observed at the 66% and 38% tibia sites with robustness increasing more with age in men than in women (P=0.006 to 0.042). Post-hoc analyses indicated no sex differences prior to 13years-of-age, and notable exceptions to increasing robustness with age at the 4% radial and 66% tibial sites, which exhibited reduced robustness in age groups close to peak height velocity. In conclusion, the present results suggest that very little sexual dimorphism in long bone robustness exists prior to puberty, and that divergence occurs primarily after cessation of longitudinal growth. A period of relative diaphyseal slenderness was identified at age-groups coinciding with the adolescent growth spurt, which may be related to the relatively high incidence of frank and stress fracture in adolescents. Copyright © 2016 Elsevier Inc. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Knott, C.N.; Waddington, C.J.; Albergo, S.

The interactions of {sup 36}Ar projectile nuclei with energies of 361, 546, and 765 MeV/nucleon and {sup 40}Ar nuclei with 352 MeV/nucleon, have been studied in a liquid-hydrogen target as part of a program to study interactions of relevance to the problem of cosmic-ray propagation in the interstellar medium. We have measured the cross sections for the production of isotopic fragments of the projectile nuclei in these interactions. The variations of these cross sections with mass, charge, and energy, are examined for insights into any systematic features of this type of fragmentation reaction that might aid predictions of other, unmeasuredmore » cross sections. These cross sections are also compared with the values derived from the most commonly used prediction techniques. It is suggested that these techniques could be improved by taking account of the systematic features identified here. {copyright} {ital 1997} {ital The American Physical Society}« less

Cross-Modal Interactions in the Experience of Musical Performances: Physiological Correlates

ERIC Educational Resources Information Center

Chapados, Catherine; Levitin, Daniel J.

2008-01-01

This experiment was conducted to investigate cross-modal interactions in the emotional experience of music listeners. Previous research showed that visual information present in a musical performance is rich in expressive content, and moderates the subjective emotional experience of a participant listening and/or observing musical stimuli [Vines,…

Reflections on Online Learning Designs and Cross-Institutional Research Collaborations: Revisiting "Classrooms without Walls" in Two Australian Universities

ERIC Educational Resources Information Center

Rossi, Dolene; van Rensburg, Henriette; Clark, Damien; Harreveld, R. E.; Beer, Colin; Danaher, P. A.

2015-01-01

The article on which this paper reflects ["Exploring a Cross-Institutional Research Collaboration and Innovation: Deploying Social Software and Web 2.0 Technologies to Investigate Online Learning Designs and Interactions in Two Australian Universities"] presented elements of a research project investigating learning interactions in…

Assembly of bipolar microtubule structures by passive cross-linkers and molecular motors

NASA Astrophysics Data System (ADS)

Johann, D.; Goswami, D.; Kruse, K.

2016-06-01

During cell division, sister chromatids are segregated by the mitotic spindle, a bipolar assembly of interdigitating antiparallel polar filaments called microtubules. The spindle contains the midzone, a stable region of overlapping antiparallel microtubules, that is essential for maintaining bipolarity. Although a lot is known about the molecular players involved, the mechanism underlying midzone formation and maintenance is still poorly understood. We study the interaction of polar filaments that are cross-linked by molecular motors moving directionally and by passive cross-linkers diffusing along microtubules. Using a particle-based stochastic model, we find that the interplay of motors and passive cross-linkers can generate a stable finite overlap between a pair of antiparallel polar filaments. We develop a mean-field theory to study this mechanism in detail and investigate the influence of steric interactions between motors and passive cross-linkers on the overlap dynamics. In the presence of interspecies steric interactions, passive cross-linkers mimic the behavior of molecular motors and stable finite overlaps are generated even for non-cross-linking motors. Finally, we develop a mean-field theory for a bundle of aligned polar filaments and show that they can self-organize into a spindlelike pattern. Our work suggests possible ways as to how cells can generate spindle midzones and control their extensions.

In-Culture Cross-Linking of Bacterial Cells Reveals Large-Scale Dynamic Protein-Protein Interactions at the Peptide Level.

PubMed

de Jong, Luitzen; de Koning, Edward A; Roseboom, Winfried; Buncherd, Hansuk; Wanner, Martin J; Dapic, Irena; Jansen, Petra J; van Maarseveen, Jan H; Corthals, Garry L; Lewis, Peter J; Hamoen, Leendert W; de Koster, Chris G

2017-07-07

Identification of dynamic protein-protein interactions at the peptide level on a proteomic scale is a challenging approach that is still in its infancy. We have developed a system to cross-link cells directly in culture with the special lysine cross-linker bis(succinimidyl)-3-azidomethyl-glutarate (BAMG). We used the Gram-positive model bacterium Bacillus subtilis as an exemplar system. Within 5 min extensive intracellular cross-linking was detected, while intracellular cross-linking in a Gram-negative species, Escherichia coli, was still undetectable after 30 min, in agreement with the low permeability in this organism for lipophilic compounds like BAMG. We were able to identify 82 unique interprotein cross-linked peptides with <1% false discovery rate by mass spectrometry and genome-wide database searching. Nearly 60% of the interprotein cross-links occur in assemblies involved in transcription and translation. Several of these interactions are new, and we identified a binding site between the δ and β' subunit of RNA polymerase close to the downstream DNA channel, providing a clue into how δ might regulate promoter selectivity and promote RNA polymerase recycling. Our methodology opens new avenues to investigate the functional dynamic organization of complex protein assemblies involved in bacterial growth. Data are available via ProteomeXchange with identifier PXD006287.

Cross-interactions between the Alzheimer Disease Amyloid-β Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis.

PubMed

Luo, Jinghui; Wärmländer, Sebastian K T S; Gräslund, Astrid; Abrahams, Jan Pieter

2016-08-05

Many protein folding diseases are intimately associated with accumulation of amyloid aggregates. The amyloid materials formed by different proteins/peptides share many structural similarities, despite sometimes large amino acid sequence differences. Some amyloid diseases constitute risk factors for others, and the progression of one amyloid disease may affect the progression of another. These connections are arguably related to amyloid aggregates of one protein being able to directly nucleate amyloid formation of another, different protein: the amyloid cross-interaction. Here, we discuss such cross-interactions between the Alzheimer disease amyloid-β (Aβ) peptide and other amyloid proteins in the context of what is known from in vitro and in vivo experiments, and of what might be learned from clinical studies. The aim is to clarify potential molecular associations between different amyloid diseases. We argue that the amyloid cascade hypothesis in Alzheimer disease should be expanded to include cross-interactions between Aβ and other amyloid proteins. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

How do walkers behave when crossing the way of a mobile robot that replicates human interaction rules?

PubMed

Vassallo, Christian; Olivier, Anne-Hélène; Souères, Philippe; Crétual, Armel; Stasse, Olivier; Pettré, Julien

2018-02-01

Previous studies showed the existence of implicit interaction rules shared by human walkers when crossing each other. Especially, each walker contributes to the collision avoidance task and the crossing order, as set at the beginning, is preserved along the interaction. This order determines the adaptation strategy: the first arrived increases his/her advance by slightly accelerating and changing his/her heading, whereas the second one slows down and moves in the opposite direction. In this study, we analyzed the behavior of human walkers crossing the trajectory of a mobile robot that was programmed to reproduce this human avoidance strategy. In contrast with a previous study, which showed that humans mostly prefer to give the way to a non-reactive robot, we observed similar behaviors between human-human avoidance and human-robot avoidance when the robot replicates the human interaction rules. We discuss this result in relation with the importance of controlling robots in a human-like way in order to ease their cohabitation with humans. Copyright © 2017 Elsevier B.V. All rights reserved.

From eV to EeV: Neutrino cross sections across energy scales

NASA Astrophysics Data System (ADS)

Formaggio, J. A.; Zeller, G. P.

2012-07-01

Since its original postulation by Wolfgang Pauli in 1930, the neutrino has played a prominent role in our understanding of nuclear and particle physics. In the intervening 80 years, scientists have detected and measured neutrinos from a variety of sources, both man made and natural. Underlying all of these observations, and any inferences we may have made from them, is an understanding of how neutrinos interact with matter. Knowledge of neutrino interaction cross sections is an important and necessary ingredient in any neutrino measurement. With the advent of new precision experiments, the demands on our understanding of neutrino interactions is becoming even greater. The purpose of this article is to survey our current knowledge of neutrino cross sections across all known energy scales: from the very lowest energies to the highest that we hope to observe. The article covers a wide range of neutrino interactions including coherent scattering, neutrino capture, inverse beta decay, low-energy nuclear interactions, quasielastic scattering, resonant pion production, kaon production, deep inelastic scattering, and ultrahigh energy interactions. Strong emphasis is placed on experimental data whenever such measurements are available.

Proton-Nucleus Total Cross Sections in Coupled-Channel Approach

NASA Technical Reports Server (NTRS)

Tripathi, R. K.; Wilson, John W.; Cucinotta, Francis A.

2000-01-01

Recently, nucleon-nucleon (N-N) cross sections in the medium have been extracted directly from experiment. The in-medium N-N cross sections form the basic ingredients of several heavy-ion scattering approaches including the coupled-channel approach developed at the Langley Research Center. In the present study the ratio of the real to the imaginary part of the two-body scattering amplitude in the medium was investigated. These ratios are used in combination with the in-medium N-N cross sections to calculate total proton-nucleus cross sections. The agreement is excellent with the available experimental data. These cross sections are needed for the radiation risk assessment of space missions.

Measurement of inclusive and differential cross sections in the H → ZZ * → 4ℓ decay channel in pp collisions at $$ \\sqrt{s}=13 $$ TeV with the ATLAS detector

DOE PAGES

Aaboud, M.; Aad, G.; Abbott, B.; ...

2017-10-19

Inclusive and differential fiducial cross sections of Higgs boson production in proton-proton collisions are measured in the H → ZZ * → 4ℓ decay channel. The proton-proton collision data were produced at the Large Hadron Collider at a centre-of-mass energy of 13 TeV and recorded by the ATLAS detector in 2015 and 2016, corresponding to an integrated luminosity of 36.1 fb –1. The inclusive fiducial cross section in the H → ZZ * → 4ℓ decay channel is measured to be 3.62±0.50(stat) –0.20 +0.25 (sys) fb, in agreement with the Standard Model prediction of 2.91 ± 0.13 fb. The crossmore » section is also extrapolated to the total phase space including all Standard Model Higgs boson decays. Several differential fiducial cross sections are measured for observables sensitive to the Higgs boson production and decay, including kinematic distributions of jets produced in association with the Higgs boson. Good agreement is found between data and Standard Model predictions. Here, the results are used to put constraints on anomalous Higgs boson interactions with Standard Model particles, using the pseudo-observable extension to the kappa-framework.« less

Measurement of inclusive and differential cross sections in the H → ZZ * → 4ℓ decay channel in pp collisions at $$ \\sqrt{s}=13 $$ TeV with the ATLAS detector

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aaboud, M.; Aad, G.; Abbott, B.

Inclusive and differential fiducial cross sections of Higgs boson production in proton-proton collisions are measured in the H → ZZ * → 4ℓ decay channel. The proton-proton collision data were produced at the Large Hadron Collider at a centre-of-mass energy of 13 TeV and recorded by the ATLAS detector in 2015 and 2016, corresponding to an integrated luminosity of 36.1 fb –1. The inclusive fiducial cross section in the H → ZZ * → 4ℓ decay channel is measured to be 3.62±0.50(stat) –0.20 +0.25 (sys) fb, in agreement with the Standard Model prediction of 2.91 ± 0.13 fb. The crossmore » section is also extrapolated to the total phase space including all Standard Model Higgs boson decays. Several differential fiducial cross sections are measured for observables sensitive to the Higgs boson production and decay, including kinematic distributions of jets produced in association with the Higgs boson. Good agreement is found between data and Standard Model predictions. Here, the results are used to put constraints on anomalous Higgs boson interactions with Standard Model particles, using the pseudo-observable extension to the kappa-framework.« less

Prevalence and typology of potential drug interactions occurring in primary care patients.

PubMed

Lopez-Picazo, Julio J; Ruiz, Juan C; Sanchez, Jose F; Ariza, Angeles; Aguilera, Belen; Lazaro, Dolores; Sanz, Gonzalo R

2010-06-01

To investigate the prevalence and types of potential drug interactions in primary care patients to detect risky prescriptions as an essential condition to design intervention policies leading to an improvement in patient safety. Cross-sectional descriptive study. Two areas in Spain comprising 715,661 inhabitants. 430,525 subjects with electronic medical records and assigned to a family doctor regularly updating them. On a random day, 29.4% of the population was taking medication. Of these, 73.9% were at risk of suffering interactions, and these were found in 20.6% of them. The amount of interactions was higher among people with chronic conditions, the elderly, females and polymedicated patients. From the total of interactions, 55.1% belonged to the highest clinical relevance 'A' level, and 28.3% should have been avoided. The active ingredients primarily involved were hydrochlorothiazide and ibuprofen and, when focusing on those that should be avoided, omeprazole and acenocoumarol. The most frequent 'A' interaction that should be avoided was between non-conjugated excreted benzodiazepines and proton-pump inhibitors, followed by some NSAIDs and diuretics. 1 in 20 Spanish citizens is currently undergoing a potential drug interaction, including a high rate of clinically relevant ones that should be avoided. These results confirm the existence of a serious safety issue that should be approached and where all parties involved (physicians, health services, medical societies and patients) must do our bit to improve. Health services should foster the implementation of prescription alert systems linked with electronic medical records including clinical data.

The relationship between nurse-patient interaction and meaning-in-life in cognitively intact nursing home patients.

PubMed

Haugan, Gørill

2014-01-01

To investigate the associations between nurse-patient interaction and meaning-in-life in a nursing home population. Meaning has been found to be a strong individual predictor of successful ageing and life satisfaction as well as an important psychological variable that promotes well-being. Meaning seems to serve as a mediating variable in both psychological and physical health. Connecting and communicating with others have been seen to facilitate meaning-in-life among older individuals. Cross-sectional descriptive study. The data were collected in 2008-2009 using the Nurse-Patient Interaction Scale and the Purpose-in-Life test. A total of 250 cognitively intact nursing home patients met the inclusion criteria and 202 (81%) participated. A structural equation model of the hypothesized relationship between nurse-patient interaction and meaning was tested by means of LISREL 8.8. The structural equation model fit well with the data. A significant direct relationship between nurse-patient interaction and meaning-in-life in cognitively intact nursing home patients was displayed. Nurse-patient interaction significantly relates to meaning and purpose-in-life among cognitively intact nursing home patients and might be an important resource in relation to the patient's mental health and global well-being. High-quality nurse-patient interaction and in-house activities aiming to increase patients' meaning might increase psychological and physical health, well-being and psycho-spiritual functioning in this vulnerable population. © 2013 John Wiley & Sons Ltd.

Disentangling effects of abiotic factors and biotic interactions on cross-taxon congruence in species turnover patterns of plants, moths and beetles.

PubMed

Duan, Meichun; Liu, Yunhui; Yu, Zhenrong; Baudry, Jacques; Li, Liangtao; Wang, Changliu; Axmacher, Jan C

2016-04-01

High cross-taxon congruence in species diversity patterns is essential for the use of surrogate taxa in biodiversity conservation, but presence and strength of congruence in species turnover patterns, and the relative contributions of abiotic environmental factors and biotic interaction towards this congruence, remain poorly understood. In our study, we used variation partitioning in multiple regressions to quantify cross-taxon congruence in community dissimilarities of vascular plants, geometrid and arciinid moths and carabid beetles, subsequently investigating their respective underpinning by abiotic factors and biotic interactions. Significant cross-taxon congruence observed across all taxon pairs was linked to their similar responses towards elevation change. Changes in the vegetation composition were closely linked to carabid turnover, with vegetation structure and associated microclimatic conditions proposed causes of this link. In contrast, moth assemblages appeared to be dominated by generalist species whose turnover was weakly associated with vegetation changes. Overall, abiotic factors exerted a stronger influence on cross-taxon congruence across our study sites than biotic interactions. The weak congruence in turnover observed particularly between plants and moths highlights the importance of multi-taxon approaches based on groupings of taxa with similar turnovers, rather than the use of single surrogate taxa or environmental proxies, in biodiversity assessments.

Perceptual crossing: the simplest online paradigm

PubMed Central

Auvray, Malika; Rohde, Marieke

2012-01-01

Researchers in social cognition increasingly realize that many phenomena cannot be understood by investigating offline situations only, focusing on individual mechanisms and an observer perspective. There are processes of dynamic emergence specific to online situations, when two or more persons are engaged in a real-time interaction that are more than just the sum of the individual capacities or behaviors, and these require the study of online social interaction. Auvray et al.'s (2009) perceptual crossing paradigm offers possibly the simplest paradigm for studying such online interactions: two persons, a one-dimensional space, one bit of information, and a yes/no answer. This study has provoked a lot of resonance in different areas of research, including experimental psychology, computer/robot modeling, philosophy, psychopathology, and even in the field of design. In this article, we review and critically assess this body of literature. We give an overview of both behavioral experimental research and simulated agent modeling done using the perceptual crossing paradigm. We discuss different contexts in which work on perceptual crossing has been cited. This includes the controversy about the possible constitutive role of perceptual crossing for social cognition. We conclude with an outlook on future research possibilities, in particular those that could elucidate the link between online interaction dynamics and individual social cognition. PMID:22723776

Reliability, Factor Structure, and Measurement Invariance of the Dominic Interactive Across European Countries: Cross-Country Utility of a Child Mental Health Self-Report

PubMed Central

Kuijpers, Rowella C. W. M.; Otten, Roy; Vermulst, Ad A.; Bitfoi, Adina; Goelitz, Dietmar; Koç, Ceren; Mihova, Zlatka; Pez, Ondine; Carta, Mauro; Keyes, Katherine; Lesinskiene, Sigita; Engels, Rutger C. M. E.; Kovess, Viviane

2015-01-01

Large-scale international surveys are important to globally evaluate, monitor, and promote children's mental health. However, use of young children's self-reports in these studies is still controversial. The Dominic Interactive, a computerized DSM-IV–based child mental health self-report questionnaire, has unique characteristics that may make it preeminently appropriate for usage in cross-country comparisons. This study aimed to determine scale score reliabilities (omega) of the Dominic Interactive in a sample of 8,135 primary school children, ages 6–11 years old, in 7 European countries, to confirm the proposed 7-scale factor structure, and to test for measurement invariance of scale and item scores across countries. Omega reliability values for scale scores were good to high in every country, and the factor structure was confirmed for all countries. A thorough examination of measurement invariance provided evidence for cross-country test score comparability of 5 of the 7 scales and partial scale score invariance of 2 anxiety scales. Possible explanations for this partial invariance include cross-country differences in conceptualizing items and defining what is socially and culturally acceptable anxiety. The convincing evidence for validity of score interpretation makes the Dominic Interactive an indispensable tool for cross-country screening purposes. PMID:26237209

Genetic variation and co-variation for fitness between intra-population and inter-population backgrounds in the red flour beetle, Tribolium castaneum

PubMed Central

Drury, Douglas W.; Wade, Michael J.

2010-01-01

Hybrids from crosses between populations of the flour beetle, Tribolium castaneum, express varying degrees of inviability and morphological abnormalities. The proportion of allopatric population hybrids exhibiting these negative hybrid phenotypes varies widely, from 3% to 100%, depending upon the pair of populations crossed. We crossed three populations and measured two fitness components, fertility and adult offspring numbers from successful crosses, to determine how genes segregating within populations interact in inter-population hybrids to cause the negative phenotypes. With data from crosses of 40 sires from each of three populations to groups of 5 dams from their own and two divergent populations, we estimated the genetic variance and covariance for breeding value of fitness between the intra- and inter-population backgrounds and the sire × dam-population interaction variance. The latter component of the variance in breeding values estimates the change in genic effects between backgrounds owing to epistasis. Interacting genes with a positive effect, prior to fixation, in the sympatric background but a negative effect in the hybrid background cause reproductive incompatibility in the Dobzhansky-Muller speciation model. Thus, the sire × dam-population interaction provides a way to measure the progress toward speciation of genetically differentiating populations on a trait by trait basis using inter-population hybrids. PMID:21044199

Racial identity, social context, and race-related social cognition in African Americans during middle childhood.

PubMed

Rowley, Stephanie J; Burchinal, Margaret R; Roberts, Joanne E; Zeisel, Susan A

2008-11-01

This study examined the effect of changes in racial identity, cross-race friendships, same-race friendships, and classroom racial composition on changes in race-related social cognition from 3rd to 5th grade for 73 African American children. The goal of the study was to determine the extent to which preadolescent racial identity and social context predict expectations of racial discrimination in cross-race social interactions (social expectations). Expectations of racial discrimination were assessed using vignettes of cross-race social situations involving an African American child in a social interaction with European Americans. There were 3 major findings. First, expectations for discrimination declined slightly from 3rd to 5th grade. Second, although racial composition of children's classrooms, number of European American friends, gender, and family poverty status were largely unrelated to social expectations, having more African American friends was associated with expecting more discrimination in cross-racial interactions from 3rd to 5th grade. Third, increases in racial centrality were related to increases in discrimination expectations, and increases in public regard were associated with decreases in discrimination expectations. These data suggest that as early as 3rd grade, children are forming attitudes about their racial group that have implications for their cross-race social interactions.

In vitro studies on the effect of physical cross-linking on the biological performance of aliphatic poly(urethane urea) for blood contact applications.

PubMed

Thomas, V; Kumari, T V; Jayabalan, M

2001-01-01

The effect of physical cross-linking in candidate cycloaliphatic and hydrophobic poly(urethane urea) (4,4'-methylenebis(cyclohexylisocyanate), H(12)MDI/hydroxy-terminated polybutadiene, HTPBD/hexamethylenediamine, HDA) and poly(ether urethane urea)s (H(12)MDI/HTPBD-PTMG/HDA) on the in vitro calcification and blood-material interaction was studied. All the candidate poly(urethane urea)s and poly(ether urethane urea)s elicit acceptable hemolytic activity, cytocompatibility, calcification, and blood compatibility in vitro. The studies on blood-material interaction reveal that the present poly(urethane urea)s are superior to polystyrene microtiter plates which were used for the studies on blood-material interaction. The present investigation reveals the influence of physical cross-link density on biological interaction differently with poly(urethane urea) and poly(ether urethane urea)s. The higher the physical cross-link density in the poly(urethane urea)s, the higher the calcification and consumption of WBC in whole blood. On the other hand, the higher the physical cross-link density in the poly(ether urethane urea)s, the lesser the calcification and consumption of WBC in whole blood. However a reverse of the above trend has been observed with the platelet consumption in the poly(urethane urea)s and poly(ether urethane urea)s.

Disentangling effects of abiotic factors and biotic interactions on cross-taxon congruence in species turnover patterns of plants, moths and beetles

PubMed Central

Duan, Meichun; Liu, Yunhui; Yu, Zhenrong; Baudry, Jacques; Li, Liangtao; Wang, Changliu; Axmacher, Jan C.

2016-01-01

High cross-taxon congruence in species diversity patterns is essential for the use of surrogate taxa in biodiversity conservation, but presence and strength of congruence in species turnover patterns, and the relative contributions of abiotic environmental factors and biotic interaction towards this congruence, remain poorly understood. In our study, we used variation partitioning in multiple regressions to quantify cross-taxon congruence in community dissimilarities of vascular plants, geometrid and arciinid moths and carabid beetles, subsequently investigating their respective underpinning by abiotic factors and biotic interactions. Significant cross-taxon congruence observed across all taxon pairs was linked to their similar responses towards elevation change. Changes in the vegetation composition were closely linked to carabid turnover, with vegetation structure and associated microclimatic conditions proposed causes of this link. In contrast, moth assemblages appeared to be dominated by generalist species whose turnover was weakly associated with vegetation changes. Overall, abiotic factors exerted a stronger influence on cross-taxon congruence across our study sites than biotic interactions. The weak congruence in turnover observed particularly between plants and moths highlights the importance of multi-taxon approaches based on groupings of taxa with similar turnovers, rather than the use of single surrogate taxa or environmental proxies, in biodiversity assessments. PMID:27032533

The role of idiotypic interactions in the adaptive immune system: a belief-propagation approach

NASA Astrophysics Data System (ADS)

Bartolucci, Silvia; Mozeika, Alexander; Annibale, Alessia

2016-08-01

In this work we use belief-propagation techniques to study the equilibrium behaviour of a minimal model for the immune system comprising interacting T and B clones. We investigate the effect of the so-called idiotypic interactions among complementary B clones on the system’s activation. Our results show that B-B interactions increase the system’s resilience to noise, making clonal activation more stable, while increasing the cross-talk between different clones. We derive analytically the noise level at which a B clone gets activated, in the absence of cross-talk, and find that this increases with the strength of idiotypic interactions and with the number of T cells sending signals to the B clones. We also derive, analytically and numerically, via population dynamics, the critical line where clonal cross-talk arises. Our approach allows us to derive the B clone size distribution, which can be experimentally measured and gives important information about the adaptive immune system response to antigens and vaccination.

Experimental research on crossing shock wave boundary layer interactions

NASA Astrophysics Data System (ADS)

Settles, G. S.; Garrison, T. J.

1994-10-01

An experimental research effort of the Penn State Gas Dynamics Laboratory on the subject of crossing shock wave boundary layer interactions is reported. This three year study was supported by AFOSR Grant 89-0315. A variety of experimental techniques were employed to study the above phenomena including planar laser scattering flowfield visualization, kerosene lampblack surface flow visualization, laser-interferometer skin friction surveys, wall static pressure measurements, and flowfield five-hole probe surveys. For a model configuration producing two intersecting shock waves, measurements were made for a range of oblique shock strengths at freestream Mach numbers of 3.0 and 3.85. Additionally, measurements were made at Mach 3.85 for a configuration producing three intersecting waves. The combined experimental dataset was used to formulate the first detailed flowfield models of the crossing-shock and triple-shock wave/boundary layer interactions. The structure of these interactions was found to be similar over a broad range of interaction strengths and is dominated by a large, separated, viscous flow region.

Urban sprawl, obesity, and cancer mortality in the United States: cross-sectional analysis and methodological challenges

PubMed Central

2014-01-01

Background Urban sprawl has the potential to influence cancer mortality via direct and indirect effects on obesity, access to health services, physical activity, transportation choices and other correlates of sprawl and urbanization. Methods This paper presents a cross-sectional analysis of associations between urban sprawl and cancer mortality in urban and suburban counties of the United States. This ecological analysis was designed to examine whether urban sprawl is associated with total and obesity-related cancer mortality and to what extent these associations differed in different regions of the US. A major focus of our analyses was to adequately account for spatial heterogeneity in mortality. Therefore, we fit a series of regression models, stratified by gender, successively testing for the presence of spatial heterogeneity. Our resulting models included county level variables related to race, smoking, obesity, access to health services, insurance status, socioeconomic position, and broad geographic region as well as a measure of urban sprawl and several interactions. Our most complex models also included random effects to account for any county-level spatial autocorrelation that remained unexplained by these variables. Results Total cancer mortality rates were higher in less sprawling areas and contrary to our initial hypothesis; this was also true of obesity related cancers in six of seven U.S. regions (census divisions) where there were statistically significant associations between the sprawl index and mortality. We also found significant interactions (p < 0.05) between region and urban sprawl for total and obesity related cancer mortality in both sexes. Thus, the association between urban sprawl and cancer mortality differs in different regions of the US. Conclusions Despite higher levels of obesity in more sprawling counties in the US, mortality from obesity related cancer was not greater in such counties. Identification of disparities in cancer mortality within and between geographic regions is an ongoing public health challenge and an opportunity for further analytical work identifying potential causes of these disparities. Future analyses of urban sprawl and health outcomes should consider exploring regional and international variation in associations between sprawl and health. PMID:24393615

Urban sprawl, obesity, and cancer mortality in the United States: cross-sectional analysis and methodological challenges.

PubMed

Berrigan, David; Tatalovich, Zaria; Pickle, Linda W; Ewing, Reid; Ballard-Barbash, Rachel

2014-01-06

Urban sprawl has the potential to influence cancer mortality via direct and indirect effects on obesity, access to health services, physical activity, transportation choices and other correlates of sprawl and urbanization. This paper presents a cross-sectional analysis of associations between urban sprawl and cancer mortality in urban and suburban counties of the United States. This ecological analysis was designed to examine whether urban sprawl is associated with total and obesity-related cancer mortality and to what extent these associations differed in different regions of the US. A major focus of our analyses was to adequately account for spatial heterogeneity in mortality. Therefore, we fit a series of regression models, stratified by gender, successively testing for the presence of spatial heterogeneity. Our resulting models included county level variables related to race, smoking, obesity, access to health services, insurance status, socioeconomic position, and broad geographic region as well as a measure of urban sprawl and several interactions. Our most complex models also included random effects to account for any county-level spatial autocorrelation that remained unexplained by these variables. Total cancer mortality rates were higher in less sprawling areas and contrary to our initial hypothesis; this was also true of obesity related cancers in six of seven U.S. regions (census divisions) where there were statistically significant associations between the sprawl index and mortality. We also found significant interactions (p < 0.05) between region and urban sprawl for total and obesity related cancer mortality in both sexes. Thus, the association between urban sprawl and cancer mortality differs in different regions of the US. Despite higher levels of obesity in more sprawling counties in the US, mortality from obesity related cancer was not greater in such counties. Identification of disparities in cancer mortality within and between geographic regions is an ongoing public health challenge and an opportunity for further analytical work identifying potential causes of these disparities. Future analyses of urban sprawl and health outcomes should consider exploring regional and international variation in associations between sprawl and health.

The Application of an Emerging Technique for Protein–Protein Interaction Interface Mapping: The Combination of Photo-Initiated Cross-Linking Protein Nanoprobes with Mass Spectrometry

PubMed Central

Ptáčková, Renata; Ječmen, Tomáš; Novák, Petr; Hudeček, Jiří; Stiborová, Marie; Šulc, Miroslav

2014-01-01

Protein–protein interaction was investigated using a protein nanoprobe capable of photo-initiated cross-linking in combination with high-resolution and tandem mass spectrometry. This emerging experimental approach introduces photo-analogs of amino acids within a protein sequence during its recombinant expression, preserves native protein structure and is suitable for mapping the contact between two proteins. The contact surface regions involved in the well-characterized interaction between two molecules of human 14-3-3ζ regulatory protein were used as a model. The employed photo-initiated cross-linking techniques extend the number of residues shown to be within interaction distance in the contact surface of the 14-3-3ζ dimer (Gln8–Met78). The results of this study are in agreement with our previously published data from molecular dynamic calculations based on high-resolution chemical cross-linking data and Hydrogen/Deuterium exchange mass spectrometry. The observed contact is also in accord with the 14-3-3ζ X-ray crystal structure (PDB 3dhr). The results of the present work are relevant to the structural biology of transient interaction in the 14-3-3ζ protein, and demonstrate the ability of the chosen methodology (the combination of photo-initiated cross-linking protein nanoprobes and mass spectrometry analysis) to map the protein-protein interface or regions with a flexible structure. PMID:24865487

Comparison of x-ray cross sections for diagnostic and therapeutic medical physics.

PubMed

Boone, J M; Chavez, A E

1996-12-01

The purpose of this technical report is to make available an up-to-date source of attenuation coefficient data to the medical physics community, and to compare these data with other more familiar sources. Data files from Lawrence Livermore National Laboratory (in Livermore, CA) were truncated to match the needs of the medical physics community, and an interpolation routine was written to calculate a continuous set of cross sections spanning energies from 1 keV to 50 MeV. Coefficient data are available for elements Z = 1 through Z = 100. Values for mass attenuation coefficients, mass-energy-transfer coefficients, and mass-energy absorption coefficients are produced by a single computer subroutine. In addition to total interaction cross sections, the cross sections for photoelectric, Rayleigh, Compton, pair, and some triplet interactions are also produced by this single program. The coefficients were compared to the 1970 data of Storm and Israel over the energy interval from 1 to 1000 keV; for elements 10, 20, 30, 40, 50, 60, 70, and 80, the average positive difference between the Storm and Israel coefficients and the coefficients reported here are 1.4%, 2.7%, and 2.6%, for the mass attenuation, mass energy-transfer, and mass-energy absorption coefficients, respectively. The 1969 data compilation of mass attenuation coefficients from McMaster et al. were also compared with the newer LLNL data. Over the energy region from 10 keV to 1000 keV, and from elements Z = 1 to Z = 82 (inclusive), the overall average difference was 1.53% (sigma = 0.85%). While the overall average difference was small, there was larger variation (> 5%) between cross sections for some elements. In addition to coefficient data, other useful data such as the density, atomic weight, K, L1, L2, L3, M, and N edges, and numerous characteristic emission energies are output by the program, depending on a single input variable. The computer source code, written in C, can be accessed and downloaded from the World Wide Web at: http:@www.aip.org/epaps/epaps.html [E-MPHSA-23-1977].

Positron scattering from molecular hydrogen

NASA Astrophysics Data System (ADS)

Machacek, J. R.; Anderson, E. K.; Makochekanwa, C.; Buckman, S. J.; Sullivan, J. P.

2013-10-01

We present results for total and partial cross sections for positron scattering from H2. The total scattering and positronium formation cross sections are reported between 0.5 and 200 eV. Total quasielastic and inelastic scattering cross sections are reported for energies between the positronium formation threshold and 50 eV, with quasielastic differential scattering cross sections reported at 1, 3, 5, 7, and 10 eV. Our results are compared with previous work, both experimental and theoretical, with particular attention paid to the region below the positronium formation threshold, where there are apparent discrepancies in previous work. A discussion of possible reasons for discrepancies between this and previous work is presented, including a focus on known systematic effects in the experimental results.

Interactions between Super Typhoon Megi (2010) and the Monsoon Gyre

NASA Astrophysics Data System (ADS)

Peng, M.; Li, T.; Bi, M.; Shen, X.

2015-12-01

Accurate prediction of tropical cyclone track is critical for high-impact weather preparedness, especially as the storm is near the coastal region. The track prediction for super typhoon Megi (2010) in the western Pacific was notoriously bad as most operational models predicated a mainly westward movement while Megi actually made a northward turning after it has crossed the Philippines islands. In this study, we try to understand this rather irregular motion for Megi. Examination of NCEP reanalyzed fields indicated that during this period a low-frequency (10-60-day) monsoon gyre in the vicinity of Megi may have interactions with the latter. To understand the effect of the low-frequency mode on the movement of Megi, numerical experiments were designed and conducted. The total flow from the analyzed field is separated into 1) a slowly varying background state, 2) a 10-60-day low frequency component representing the monsoon gyre, and 3) a 10-day high-pass filtered component representing Megi. In the control experiment, the total field containing all three components is used as the initial and lateral boundary conditions, and the WRF model is able to simulate Megi's sharp northward turning successfully. In the second experiment, the 10-60-day mode is removed from the initial and lateral boundary fields. In the absence of the low-frequency mode, Megi moves westward and only slightly northwestward without turning north. When the vortex representing Megi was removed, the movement of the monsoon gyre was also affected. These experiments indicated strong interactions between Megi and the monsoon gyre. The interactions and the way the monsoon gyre actually affected the track of Megi will be discussed in the presentation.

Total cross sections for ultracold neutrons scattered from gases

DOE PAGES

Seestrom, Susan Joyce; Adamek, Evan R.; Barlow, Dave; ...

2017-01-30

Here, we have followed up on our previous measurements of upscattering of ultracold neutrons (UCNs) from a series of gases by making measurements of total cross sections on the following gases hydrogen, ethane, methane, isobutene, n-butane, ethylene, water vapor, propane, neopentane, isopropyl alcohol, and 3He. The values of these cross sections are important for estimating the loss rate of trapped neutrons due to residual gas and are relevant to neutron lifetime measurements using UCNs. The effects of the UCN velocity and path-length distributions were accounted for in the analysis using a Monte Carlo transport code. Results are compared to ourmore » previous measurements and with the known absorption cross section for 3He scaled to our UCN energy. We find that the total cross sections for the hydrocarbon gases are reasonably described by a function linear in the number of hydrogen atoms in the molecule.« less

Prevalence of Potential and Clinically Relevant Statin-Drug Interactions in Frail and Robust Older Inpatients.

PubMed

Thai, Michele; Hilmer, Sarah; Pearson, Sallie-Anne; Reeve, Emily; Gnjidic, Danijela

2015-10-01

A significant proportion of older people are prescribed statins and are also exposed to polypharmacy, placing them at increased risk of statin-drug interactions. To describe the prevalence rates of potential and clinically relevant statin-drug interactions in older inpatients according to frailty status. A cross-sectional study of patients aged ≥65 years who were prescribed a statin and were admitted to a teaching hospital between 30 July and 10 October 2014 in Sydney, Australia, was conducted. Data on socio-demographics, comorbidities and medications were collected using a standardized questionnaire. Potential statin-drug interactions were defined if listed in the Australian Medicines Handbook and three international drug information sources: the British National Formulary, Drug Interaction Facts and Drug-Reax(®). Clinically relevant statin-drug interactions were defined as interactions with the highest severity rating in at least two of the three international drug information sources. Frailty was assessed using the Reported Edmonton Frail Scale. A total of 180 participants were recruited (median age 78 years, interquartile range 14), 35.0% frail and 65.0% robust. Potential statin-drug interactions were identified in 10% of participants, 12.7% of frail participants and 8.5% of robust participants. Clinically relevant statin-drug interactions were identified in 7.8% of participants, 9.5% of frail participants and 6.8% of robust participants. Depending on the drug information source used, the prevalence rates of potential and clinically relevant statin-drug interactions ranged between 14.4 and 35.6% and between 14.4 and 20.6%, respectively. In our study of frail and robust older inpatients taking statins, the overall prevalence of potential statin-drug interactions was low and varied significantly according to the drug information source used.

Smell and Taste Dysfunction Is Associated with Higher Serum Total Cholesterol Concentrations in Chinese Adults.

PubMed

Huang, Zhe; Huang, Shue; Cong, Hongliang; Li, Zheng; Li, Junjuan; Keller, Kathleen L; Shearer, Gregory C; Kris-Etherton, Penny M; Wu, Shouling; Gao, Xiang

2017-08-01

Background: Several lipid-related hormones and peptides, such as glucagon-like peptide-1 and leptin, are involved in the regulation of taste and smell function. However, to our knowledge, it remains unknown whether these chemosensory functions are associated with lipid profiles. Objective: We examined the cross-sectional association between taste and smell dysfunction and blood cholesterol concentrations. Methods: With the use of a questionnaire, we assessed chronic smell and taste dysfunction in 12,627 Chinese participants (10,418 men and 2209 women; mean age: 54.4 y) who did not take hypolipidemic agents. Participants were categorized into 3 groups based on the number of smell and taste dysfunctions, ranging from 0 (best) to 2 (worst). A general linear model was used to test differences in serum concentrations of total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides (TGs) across groups with different smell and taste status after adjusting for age, sex, education, occupation, smoking, drinking, obesity, and history of cardiovascular disease, cancer, and head injury. Results: The prevalence of smell and taste dysfunction was 2.4% and 1.2%, respectively. Worse smell and taste dysfunction was associated with higher total cholesterol concentrations ( P -trend = 0.005). No significant differences were observed in LDL cholesterol, HDL cholesterol, and TG concentrations across groups with different numbers of chemosensory dysfunctions ( P -trend > 0.1 for all). The associations between chemosensory dysfunction and total cholesterol concentrations were more pronounced in participants aged ≤60 y and in those who were nonsmokers relative to their counterparts ( P -interaction < 0.05 for all). Conclusions: In this large cross-sectional study, chemosensory dysfunction was associated with higher serum total cholesterol concentrations among Chinese adults. Prospective studies are needed to investigate the temporal relation between these chemosensory dysfunctions and hypercholesterolemia. © 2017 American Society for Nutrition.

Validation of Cross Sections for Monte Carlo Simulation of the Photoelectric Effect

NASA Astrophysics Data System (ADS)

Han, Min Cheol; Kim, Han Sung; Pia, Maria Grazia; Basaglia, Tullio; Batič, Matej; Hoff, Gabriela; Kim, Chan Hyeong; Saracco, Paolo

2016-04-01

Several total and partial photoionization cross section calculations, based on both theoretical and empirical approaches, are quantitatively evaluated with statistical analyses using a large collection of experimental data retrieved from the literature to identify the state of the art for modeling the photoelectric effect in Monte Carlo particle transport. Some of the examined cross section models are available in general purpose Monte Carlo systems, while others have been implemented and subjected to validation tests for the first time to estimate whether they could improve the accuracy of particle transport codes. The validation process identifies Scofield's 1973 non-relativistic calculations, tabulated in the Evaluated Photon Data Library (EPDL), as the one best reproducing experimental measurements of total cross sections. Specialized total cross section models, some of which derive from more recent calculations, do not provide significant improvements. Scofield's non-relativistic calculations are not surpassed regarding the compatibility with experiment of K and L shell photoionization cross sections either, although in a few test cases Ebel's parameterization produces more accurate results close to absorption edges. Modifications to Biggs and Lighthill's parameterization implemented in Geant4 significantly reduce the accuracy of total cross sections at low energies with respect to its original formulation. The scarcity of suitable experimental data hinders a similar extensive analysis for the simulation of the photoelectron angular distribution, which is limited to a qualitative appraisal.

Energy economy in the actomyosin interaction: lessons from simple models.

PubMed

Lehman, Steven L

2010-01-01

The energy economy of the actomyosin interaction in skeletal muscle is both scientifically fascinating and practically important. This chapter demonstrates how simple cross-bridge models have guided research regarding the energy economy of skeletal muscle. Parameter variation on a very simple two-state strain-dependent model shows that early events in the actomyosin interaction strongly influence energy efficiency, and late events determine maximum shortening velocity. Addition of a weakly-bound state preceding force production allows weak coupling of cross-bridge mechanics and ATP turnover, so that a simple three-state model can simulate the velocity-dependence of ATP turnover. Consideration of the limitations of this model leads to a review of recent evidence regarding the relationship between ligand binding states, conformational states, and macromolecular structures of myosin cross-bridges. Investigation of the fine structure of the actomyosin interaction during the working stroke continues to inform fundamental research regarding the energy economy of striated muscle.

The nongravitational interactions of dark matter in colliding galaxy clusters.

PubMed

Harvey, David; Massey, Richard; Kitching, Thomas; Taylor, Andy; Tittley, Eric

2015-03-27

Collisions between galaxy clusters provide a test of the nongravitational forces acting on dark matter. Dark matter's lack of deceleration in the "bullet cluster" collision constrained its self-interaction cross section σ(DM)/m < 1.25 square centimeters per gram (cm(2)/g) [68% confidence limit (CL)] (σ(DM), self-interaction cross section; m, unit mass of dark matter) for long-ranged forces. Using the Chandra and Hubble Space Telescopes, we have now observed 72 collisions, including both major and minor mergers. Combining these measurements statistically, we detect the existence of dark mass at 7.6σ significance. The position of the dark mass has remained closely aligned within 5.8 ± 8.2 kiloparsecs of associated stars, implying a self-interaction cross section σ(DM)/m < 0.47 cm(2)/g (95% CL) and disfavoring some proposed extensions to the standard model. Copyright © 2015, American Association for the Advancement of Science.

Can dimensions of national culture predict cross-national differences in medical communication?

PubMed

Meeuwesen, Ludwien; van den Brink-Muinen, Atie; Hofstede, Geert

2009-04-01

This study investigated at a country level how cross-national differences in medical communication can be understood from the first four of Hofstede's cultural dimensions, i.e. power distance, uncertainty avoidance, individualism/collectivism and masculinity/femininity, together with national wealth. A total of 307 general practitioners (GPs) and 5820 patients from Belgium, Estonia, Germany, Great Britain, the Netherlands, Poland, Romania, Spain, Sweden and Switzerland participated in the study. Medical communication was videotaped and assessed using Roter's interaction analysis system (RIAS). Additional context information of physicians (gender, job satisfaction, risk-taking and belief of psychological influence on diseases) and patients (gender, health condition, diagnosis and medical encounter expectations) was gathered by using questionnaires. Countries differ considerably form each other in terms of culture dimensions. The larger a nation's power distance, the less room there is for unexpected information exchange and the shorter the consultations are. Roles are clearly described and fixed. The higher the level of uncertainty avoidance, the less attention is given to rapport building, e.g. less eye contact. In 'masculine' countries there is less instrumental communication in the medical interaction, which was contrary to expectations. In wealthy countries, more attention is given to psychosocial communication. The four culture dimensions, together with countries' wealth, contribute importantly to the understanding of differences in European countries' styles of medical communication. Their predictive power reaches much further than explanations along the north/south or east/west division of Europe. The understanding of these cross-national differences is a precondition for the prevention of intercultural miscommunication. Improved understanding may occur at microlevel in the medical encounter, as well as on macrolevel in pursuing more effective cooperation and integration of European health care policies.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ray, L.; Hoffmann, G.W.; Thaler, R.M.

The treatment of the Coulomb interaction in the multiple scattering theories of Kerman-McManus-Thaler and Watson is examined in detail. By neglecting virtual Coulomb excitations, the lowest order Coulomb term in the Watson optical potential is shown to be a convolution of the point Coulomb interaction with the distributed nuclear charge, while the equivalent Kerman-McManus-Thaler Coulomb potential is obtained from an averaged, single-particle Coulombic T matrix. The Kerman-McManus-Thaler Coulomb potential is expressed as the Watson Coulomb term plus additional Coulomb-nuclear and Coulomb-Coulomb cross terms, and the omission of the extra terms in usual Kerman-McManus-Thaler applications leads to negative infinite total reactionmore » cross section predictions and incorrect pure Coulomb scattering limits. Approximations are presented which eliminate these anomalies. Using the two-potential formula, the full projectile-nucleus T matrix is separated into two terms, one resulting from the distributed nuclear charge and the other being a Coulomb distorted nuclear T matrix. It is shown that the error resulting from the omission of the Kerman-McManus-Thaler Coulomb terms is effectively removed when the pure Coulomb T matrix in Kerman-McManus-Thaler is replaced by the analogous quantity in the Watson approach. Using the various approximations, theoretical angular distributions are obtained for 800 MeV p+/sup 208/Pb elastic scattering and compared with experimental data.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yokosawa, A.

Spin physics activities at medium and high energies became significantly active when polarized targets and polarized beams became accessible for hadron-hadron scattering experiments. My overview of spin physics will be inclined to the study of strong interaction using facilities at Argonne ZGS, Brookhaven AGS (including RHIC), CERN, Fermilab, LAMPF, an SATURNE. In 1960 accelerator physicists had already been convinced that the ZGS could be unique in accelerating a polarized beam; polarized beams were being accelerated through linear accelerators elsewhere at that time. However, there was much concern about going ahead with the construction of a polarized beam because (i) themore » source intensity was not high enough to accelerate in the accelerator, (ii) the use of the accelerator would be limited to only polarized-beam physics, that is, proton-proton interaction, and (iii) p-p elastic scattering was not the most popular topic in high-energy physics. In fact, within spin physics, [pi]-nucleon physics looked attractive, since the determination of spin and parity of possible [pi]p resonances attracted much attention. To proceed we needed more data beside total cross sections and elastic differential cross sections; measurements of polarization and other parameters were urgently needed. Polarization measurements had traditionally been performed by analyzing the spin of recoil protons. The drawbacks of this technique are: (i) it involves double scattering, resulting in poor accuracy of the data, and (ii) a carbon analyzer can only be used for a limited region of energy.« less

Physical modeling of vortical cross-step flow in the American paddlefish, Polyodon spathula

PubMed Central

Brooks, Hannah; Haines, Grant E.; Lin, M. Carly

2018-01-01

Vortical cross-step filtration in suspension-feeding fish has been reported recently as a novel mechanism, distinct from other biological and industrial filtration processes. Although crossflow passing over backward-facing steps generates vortices that can suspend, concentrate, and transport particles, the morphological factors affecting this vortical flow have not been identified previously. In our 3D-printed models of the oral cavity for ram suspension-feeding fish, the angle of the backward-facing step with respect to the model’s dorsal midline affected vortex parameters significantly, including rotational, tangential, and axial speed. These vortices were comparable to those quantified downstream of the backward-facing steps that were formed by the branchial arches of preserved American paddlefish in a recirculating flow tank. Our data indicate that vortices in cross-step filtration have the characteristics of forced vortices, as the flow of water inside the oral cavity provides the external torque required to sustain forced vortices. Additionally, we quantified a new variable for ram suspension feeding termed the fluid exit ratio. This is defined as the ratio of the total open pore area for water leaving the oral cavity via spaces between branchial arches that are not blocked by gill rakers, divided by the total area for water entering through the gape during ram suspension feeding. Our experiments demonstrated that the fluid exit ratio in preserved paddlefish was a significant predictor of the flow speeds that were quantified anterior of the rostrum, at the gape, directly dorsal of the first ceratobranchial, and in the forced vortex generated by the first ceratobranchial. Physical modeling of vortical cross-step filtration offers future opportunities to explore the complex interactions between structural features of the oral cavity, vortex parameters, motile particle behavior, and particle morphology that determine the suspension, concentration, and transport of particles within the oral cavity of ram suspension-feeding fish. PMID:29561890

Implementing Total Quality Management in a University Setting.

ERIC Educational Resources Information Center

Coate, L. Edwin

1991-01-01

Oregon State University implemented Total Quality Management in nine phases: exploration; establishing a pilot study team; defining customer needs; adopting the breakthrough planning process; performing breakthrough planning in divisions; forming daily management teams; initiating cross-functional pilot projects; implementing cross-functional…

Variation in Differential and Total Cross Sections Due to Different Radial Wave Functions

ERIC Educational Resources Information Center

Williamson, W., Jr.; Greene, T.

1976-01-01

Three sets of analytical wave functions are used to calculate the Na (3s---3p) transition differential and total electron excitation cross sections by Born approximations. Results show expected large variations in values. (Author/CP)

Total electron scattering cross sections of some important biomolecules at 0.2-6.0 keV energies

NASA Astrophysics Data System (ADS)

Gurung, Meera Devi; Ariyasinghe, W. M.

2017-12-01

The total electron scattering cross sections (TCS) of five nucleic bases (adenine, cytosine, guanine, thymine and uracil), phosphoric acid, three amino acids (glycine, lysine, and L-histidine), D-glucose, alpha-D-glucose, tetrahydropyran (THP), 3-hydroxytetrahydrofuran and furan have been determined in the energy range 0.2-6.0 keV using a simple model based on the effective atomic total electron scattering cross sections (EATCS). The reliability of the model is confirmed by comparing the determined TCS with the predictions of those by existing theoretical models.

Total photoproduction cross section measurement at HERA energies

NASA Astrophysics Data System (ADS)

Ahmed, T.; Andreev, V.; Andrieu, B.; Arpagaus, M.; Babaev, A.; Bärwolff, H.; Bán, J.; Baranov, P.; Barrelet, E.; Bartel, W.; Bassler, U.; Beck, G. A.; Beck, H. P.; Behrend, H.-J.; Belousov, A.; Berger, Ch.; Bergstein, H.; Bernardi, G.; Bernet, R.; Berthon, U.; Bertrand-Coremans, G.; Besançon, M.; Biddulph, P.; Binder, E.; Bizot, J. C.; Blobel, V.; Borras, K.; Bosetti, P. C.; Boudry, V.; Bourdarios, C.; Brasse, F.; Braun, U.; Braunschweig, W.; Brisson, V.; Bruncko, D.; Bürger, J.; Büsser, F. W.; Buniatian, A.; Burke, S.; Buschhorn, G.; Campbell, A. J.; Carli, T.; Charles, F.; Clarke, D.; Clegg, A. B.; Colombo, M.; Coughlan, J. A.; Courau, A.; Coutures, Ch.; Cozzika, G.; Criegee, L.; Cvach, J.; Dainton, J. B.; Danilov, M.; Dann, A. W. E.; Dau, W. D.; David, M.; Deffur, E.; Delcourt, B.; del Buono, L.; Devel, M.; de Roeck, A.; Dingus, P.; Dollfus, C.; Dowell, J. D.; Dreis, H. B.; Drescher, A.; Duboc, J.; Düllmann, D.; Dünger, O.; Duhm, H.; Eberle, M.; Ebert, J.; Ebert, T. R.; Eckerlin, G.; Efremenko, V.; Egli, S.; Eichenberger, S.; Eichler, R.; Eisele, F.; Eisenhandler, E.; Ellis, N. N.; Ellison, R. J.; Elsen, E.; Erdmann, M.; Evrard, E.; Favart, L.; Fedotov, A.; Feeken, D.; Felst, R.; Feltesse, J.; Feng, Y.; Fensome, I. F.; Ferencei, J.; Ferrarotto, F.; Flauger, W.; Fleischer, M.; Flower, P. S.; Flügge, G.; Fomenko, A.; Fominykh, B.; Forbush, M.; Formánek, J.; Foster, J. M.; Franke, G.; Fretwurst, E.; Fuhrmann, P.; Gabathuler, E.; Gamerdinger, K.; Garvey, J.; Gayler, J.; Gellrich, A.; Gennis, M.; Gensch, U.; Genzel, H.; Gerhards, R.; Gillespie, D.; Godfrey, L.; Goerlach, U.; Goerlich, L.; Goldberg, M.; Goodall, A. M.; Gorelov, I.; Goritchev, P.; Grab, C.; Grässler, H.; Grässler, R.; Greenshaw, T.; Greif, H.; Grindhammer, G.; Gruber, C.; Haack, J.; Haidt, D.; Hajduk, L.; Hamon, O.; Handschuh, D.; Hanlon, E. M.; Hapke, M.; Harjes, J.; Hartz, P.; Haydar, R.; Haynes, W. J.; Heatherington, J.; Hedberg, V.; Hedgecock, R.; Heinzelmann, G.; Henderson, R. C. W.; Henschel, H.; Herma, R.; Herynek, I.; Hildesheim, W.; Hill, P.; Hilton, C. D.; Hladký, J.; Hoeger, K. C.; Huet, Ph.; Hufnagel, H.; Huot, N.; Ibbotson, M.; Jabiol, M. A.; Jacholkowska, A.; Jacobsson, C.; Jaffre, M.; Jönsson, L.; Johannsen, K.; Johnson, D. P.; Johnson, L.; Jung, H.; Kalmus, P. I. P.; Kasarian, S.; Kaschowitz, R.; Kasselmann, P.; Kathage, U.; Kaufmann, H. H.; Kenyon, I. R.; Kermiche, S.; Kiesling, C.; Klein, M.; Kleinwort, C.; Knies, G.; Köhler, T.; Kolanoski, H.; Kole, F.; Kolya, S. D.; Korbel, V.; Korn, M.; Kostka, P.; Kotelnikov, S. K.; Krasny, M. W.; Krehbiel, H.; Krücker, D.; Krüger, U.; Kubenka, J. P.; Küster, H.; Kuhlen, M.; Kurça, T.; Kurzhöfer, J.; Kuznik, B.; Lander, R.; Landon, M. P. J.; Langkau, R.; Lanius, P.; Laporte, J. F.; Lebedev, A.; Leuschner, A.; Leverenz, C.; Levin, D.; Levonian, S.; Ley, Ch.; Lindner, A.; Lindström, G.; Loch, P.; Lohmander, H.; Lopez, G. C.; Lüers, D.; Magnussen, N.; Malinovski, E.; Mani, S.; Marage, P.; Marks, J.; Marshall, R.; Martens, J.; Martin, R.; Martyn, H.-U.; Martyniak, J.; Masson, S.; Mavroidis, A.; Maxfield, S. J.; McMahon, S. J.; Mehta, A.; Meier, K.; Merz, T.; Meyer, C. A.; Meyer, H.; Meyer, J.; Mikocki, S.; Milone, V.; Monnier, E.; Moreau, F.; Moreels, J.; Morris, J. V.; Morton, J. M.; Müller, K.; Murín, P.; Murray, S. A.; Nagovizin, V.; Naroska, B.; Naumann, Th.; Newton, D.; Nguyen, H. K.; Niebergall, F.; Nisius, R.; Nowak, G.; Noyes, G. W.; Nyberg, M.; Oberlack, H.; Obrock, H.; Olsson, J. E.; Orenstein, S.; Ould-Saada, F.; Pascaud, C.; Patel, G. D.; Peppel, E.; Peters, S.; Phillips, H. T.; Phillips, J. P.; Pichler, Ch.; Pilgram, W.; Pitzl, D.; Prosi, R.; Raupach, F.; Rauschnabel, K.; Reimer, P.; Ribarics, P.; Riech, V.; Riedlberger, J.; Rietz, M.; Robertson, S. M.; Robmann, P.; Roosen, R.; Rostovtsev, A.; Royon, C.; Rudowicz, M.; Ruffer, M.; Rusakov, S.; Rybicki, K.; Ryseck, E.; Sacton, J.; Sahlmann, N.; Sanchez, E.; Sankey, D. P. C.; Savitsky, M.; Schacht, P.; Schleper, P.; von Schlippe, W.; Schmidt, C.; Schmidt, D.; Schmitz, W.; Schröder, V.; Schulz, M.; Schwind, A.; Scobel, W.; Seehausen, U.; Sell, R.; Seman, M.; Semenov, A.; Shekelyan, V.; Sheviakov, I.; Shooshtari, H.; Siegmon, G.; Siewert, U.; Sirois, Y.; Skillicorn, I. O.; Smirnov, P.; Smith, J. R.; Smolik, L.; Soloviev, Y.; Spitzer, H.; Staroba, P.; Steenbock, M.; Steffen, P.; Steinberg, R.; Steiner, H.; Stella, B.; Stephens, K.; Stier, J.; Strachota, J.; Straumann, U.; Struczinski, W.; Sutton, J. P.; Taylor, R. E.; Thompson, G.; Thompson, R. J.; Tichomirov, I.; Trenkel, C.; Truöl, P.; Tchernyshov, V.; Turnau, J.; Tutas, J.; Urban, L.; Usik, A.; Valkar, S.; Valkarova, A.; Vallee, C.; van Esch, P.; Vartapetian, A.; Vazdik, Y.; Vecko, M.; Verrecchia, P.; Vick, R.; Villet, G.; Vogel, E.; Wacker, K.; Walker, I. W.; Walther, A.; Weber, G.; Wegener, D.; Wegner, A.; Wellisch, H. P.; Willard, S.; Winde, M.; Winter, G.-G.; Wolff, Th.; Womersley, L. A.; Wright, A. E.; Wulff, N.; Yiou, T. P.; Áçek, J.; Závada, P.; Zeitnitz, C.; Ziaeepour, H.; Zimmer, M.; Zimmermann, W.; Zomer, F.

1993-01-01

We present first results on the total photoproduction cross section measurement with the H1 detector at HERA. The data were extracted from low Q2 collisions of 26.7 GeV electrons with 820 GeV protons. The γp total cross section has been measured by two independent methods in the γp center of mass energy range from 90 to 290 GeV. For an average center of mass energy of 195 GeV a value of σtot (γp) = 159 +/- 7 (stat.) +/- 20 (syst.) μb was obtained. Supported by the Swedish Natural Science Research Council.

Cross-linked polyethylene does not reduce wear in total knee arthroplasty.

PubMed

Lasurt-Bachs, S; Torner, P; Maculé, F; Prats, E; Menéndez-García, F; Ríos-Guillermo, J; Torrents, A

To compare two different types of inserts: Ultra-high molecular weight polyethylene (UHMWPE) and cross-linked polyethylene with a quantitative and qualitative study of polyethylene wear particles in synovial fluid 3 years after total knee arthroplasty. A prospective, randomized, controlled cohort study with blinded evaluation was carried out on 25 patients undergoing staged bilateral total knee replacement, 6 months apart. Knee arthrocentesis was performed on 12 patients 3 years after surgery, and the polyethylene particles were analyzed. No significant differences were found in the number of particles generated by the two different types of inserts at 3 years from total knee arthroplasty (3,000×: x¯ cross-linked=849.7; x¯ UHMWPE=796.9; P=.63; 20,000×: x¯ cross-linked=66.3; x¯ UHMWPE=73.1; P=.76). Likewise, no differences in the probability of finding elongated (χ 2 =0.19; P=.66) or rounded (χ 2 =1.44; P=.23) particles in both types of inserts were observed. However, the probability of finding fibrillar particles is 3.08 times greater in UHMWPE. Cross-linked polyethylene does not significantly reduce the generation of polyethylene particles in patients with total knee arthroplasty, 3 years after the surgical procedure. Copyright © 2018 SECOT. Publicado por Elsevier España, S.L.U. All rights reserved.

Sorption of adamantane phenylamide derivatives on hyper-cross-linked polystyrene from water-acetonitrile eluents

NASA Astrophysics Data System (ADS)

Shafigulin, R. V.; Konstantinov, A. V.; Bulanova, A. V.; Il'in, M. M.; Davankov, V. A.

2016-11-01

Study of the main physicochemical features of the sorption of phenylamide adamantane derivatives on hyper-cross-linked polystyrene from water-acetonitrile solutions shows that both hydrophobic and electronic interactions make a large contribution to retention, especially for a chlorine-containing derivative in which there are π- p and π- d interactions between the outer-shell electrons of the chlorine atom in addition to π- π interactions between aromatic fragments of the sorbate and sorbent.

Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states

PubMed Central

Tan, Dan; Li, Qiang; Zhang, Mei-Jun; Liu, Chao; Ma, Chengying; Zhang, Pan; Ding, Yue-He; Fan, Sheng-Bo; Tao, Li; Yang, Bing; Li, Xiangke; Ma, Shoucai; Liu, Junjie; Feng, Boya; Liu, Xiaohui; Wang, Hong-Wei; He, Si-Min; Gao, Ning; Ye, Keqiong; Dong, Meng-Qiu; Lei, Xiaoguang

2016-01-01

To improve chemical cross-linking of proteins coupled with mass spectrometry (CXMS), we developed a lysine-targeted enrichable cross-linker containing a biotin tag for affinity purification, a chemical cleavage site to separate cross-linked peptides away from biotin after enrichment, and a spacer arm that can be labeled with stable isotopes for quantitation. By locating the flexible proteins on the surface of 70S ribosome, we show that this trifunctional cross-linker is effective at attaining structural information not easily attainable by crystallography and electron microscopy. From a crude Rrp46 immunoprecipitate, it helped identify two direct binding partners of Rrp46 and 15 protein-protein interactions (PPIs) among the co-immunoprecipitated exosome subunits. Applying it to E. coli and C. elegans lysates, we identified 3130 and 893 inter-linked lysine pairs, representing 677 and 121 PPIs. Using a quantitative CXMS workflow we demonstrate that it can reveal changes in the reactivity of lysine residues due to protein-nucleic acid interaction. DOI: http://dx.doi.org/10.7554/eLife.12509.001 PMID:26952210

Neonatal Restriction of Tactile Inputs Leads to Long-Lasting Impairments of Cross-Modal Processing

PubMed Central

Röder, Brigitte; Hanganu-Opatz, Ileana L.

2015-01-01

Optimal behavior relies on the combination of inputs from multiple senses through complex interactions within neocortical networks. The ontogeny of this multisensory interplay is still unknown. Here, we identify critical factors that control the development of visual-tactile processing by combining in vivo electrophysiology with anatomical/functional assessment of cortico-cortical communication and behavioral investigation of pigmented rats. We demonstrate that the transient reduction of unimodal (tactile) inputs during a short period of neonatal development prior to the first cross-modal experience affects feed-forward subcortico-cortical interactions by attenuating the cross-modal enhancement of evoked responses in the adult primary somatosensory cortex. Moreover, the neonatal manipulation alters cortico-cortical interactions by decreasing the cross-modal synchrony and directionality in line with the sparsification of direct projections between primary somatosensory and visual cortices. At the behavioral level, these functional and structural deficits resulted in lower cross-modal matching abilities. Thus, neonatal unimodal experience during defined developmental stages is necessary for setting up the neuronal networks of multisensory processing. PMID:26600123

Making and Breaking Stereotypes: East Asian International Students' Experiences with Cross-Cultural/Racial Interactions

ERIC Educational Resources Information Center

Ritter, Zachary Stephen

2013-01-01

In response to recent budget cuts and declining revenue streams, American colleges and universities are admitting larger numbers of international students. These students add a great deal of cultural and intellectual diversity to college campuses, but they also bring racial stereotypes that can affect cross-racial interaction as well as campus…

International Students from Melbourne Describing Their Cross-Cultural Transitions Experiences: Culture Shock, Social Interaction, and Friendship Development

ERIC Educational Resources Information Center

Belford, Nish

2017-01-01

Drawing from a study that explored how international students experience cross-cultural transitions after living and studying in Melbourne for a few years, this paper, in particular, examines the participants' experiences with culture shock, social interaction, and friendship development. The findings include narratives of their personal stories…

Utilizing Mechanistic Cross-Linking Technology to Study Protein-Protein Interactions: An Experiment Designed for an Undergraduate Biochemistry Lab

ERIC Educational Resources Information Center

Finzel, Kara; Beld, Joris; Burkart, Michael D.; Charkoudian, Louise K.

2017-01-01

Over the past decade, mechanistic cross-linking probes have been used to study protein-protein interactions in natural product biosynthetic pathways. This approach is highly interdisciplinary, combining elements of protein biochemistry, organic chemistry, and computational docking. Herein, we described the development of an experiment to engage…

Integrating Cross-Cultural Interaction through Video-Communication and Virtual Worlds in Foreign Language Teaching Programs: Burden or Added Value?

ERIC Educational Resources Information Center

Jauregi, Kristi; de Graaff, Rick; Canto, Silvia

2011-01-01

Organizing and implementing telecollaboration projects in foreign language curricula is not an easy endeavour (Belz & Thorne, 2006; Guth & Helm, 2010), as pedagogical, organizational and technical issues have to be addressed before cross-cultural interaction sessions can be carried out (O'Dowd & Ritter, 2006). These issues make many teaching…

The Effectiveness of Using Cloud-Based Cross-Device IRS to Support Classical Chinese Learning

ERIC Educational Resources Information Center

Wang, Yi-Hsuan

2017-01-01

The purpose of the present study was to examine the effects of integrating a cloud-based cross-device interactive response system (CCIRS) on enhancing students' classical Chinese learning. The system is a cloud-based IRS system which provides instructors and learners with an environment in which to achieve immediate interactive learning and…

Examining the Inclusiveness of Intercollegiate Team Climate and Its Influence on Student-Athletes' Cross-Racial Interactions

ERIC Educational Resources Information Center

Jones, Willis A.; Liu, Keke; Bell, Lydia F.

2017-01-01

We examined a student subgroup often absent from diversity research: student-athletes. We explored whether intercollegiate athletic teams are promoting an open and inclusive environment and whether creating such an environment leads to more frequent and more positive cross-racial interactions. Findings reveal that overall, coaches appear to be…

A Qualitative Study of Undergraduate International Students' Everyday Experiences with Cross-Cultural Interactions and the Student Adjustment Process

ERIC Educational Resources Information Center

Burkhardt, Joan Wilkinson

2013-01-01

The purpose of this basic qualitative study was to understand how everyday cross-cultural interactions affected the adjustment of undergraduate international students attending a private research university in the northeastern United States. To fulfill this purpose, three research questions were formulated as a foundation for this investigation:…

Cross-Section Parameterizations for Pion and Nucleon Production From Negative Pion-Proton Collisions

NASA Technical Reports Server (NTRS)

Norbury, John W.; Blattnig, Steve R.; Norman, Ryan; Tripathi, R. K.

2002-01-01

Ranft has provided parameterizations of Lorentz invariant differential cross sections for pion and nucleon production in pion-proton collisions that are compared to some recent data. The Ranft parameterizations are then numerically integrated to form spectral and total cross sections. These numerical integrations are further parameterized to provide formula for spectral and total cross sections suitable for use in radiation transport codes. The reactions analyzed are for charged pions in the initial state and both charged and neutral pions in the final state.

The multistate impact parameter method for molecular charge exchange in nitrogen

NASA Technical Reports Server (NTRS)

Ioup, J. W.

1980-01-01

The multistate impact parameter method is applied to the calculation of total cross sections for low energy change transfer between nitrogen ions and nitrogen molecules. Experimental data showing the relationships between total cross section and ion energy for various pressures and electron ionization energies were obtained. Calculated and experimental cross section values from the work are compared with the experimental and theoretical results of other investigators.

P(P bar)P elastic scattering and cosmic ray data

NASA Technical Reports Server (NTRS)

FAZAL-E-ALEEM; Saleem, M.

1985-01-01

It is shown that the total cross section for pp elastic scattering at cosmic ray energies, as well as the total cross section, the slope parameter b(s,t) and the differential cross section for small momentum transfer at ISR and collider energies for p(p)p elastic scattering can be simultaneously fitted by using a simple Regge pole model. The results of this theory is discussed in detail.

Growth, carcass and meat quality traits in beef from Angus, Hereford and cross-breed grazing steers, and their association with SNPs in genes related to fat deposition metabolism.

PubMed

Papaleo Mazzucco, J; Goszczynski, D E; Ripoli, M V; Melucci, L M; Pardo, A M; Colatto, E; Rogberg-Muñoz, A; Mezzadra, C A; Depetris, G J; Giovambattista, G; Villarreal, E L

2016-04-01

Grazing steers from Angus and Hereford breeds, their cross-breeds and a three-way cross-breed (Limousin × Angus-Hereford) were measured for growth, carcass and meat quality traits. Breed effects were studied, and the association of SNPs with fat deposition and fatty acid (FA) composition (leptin, melanocortin-4 receptor, stearoyl-CoA desaturase, FA synthase and thyroglobulin) was tested. Limousin cross-breed showed the greatest final body weight, ultrasound rib eye area, dressing percentage, carcass and leg length, and the lowest backfat thickness and intramuscular fat content. Genetic groups had similar pH, shear force, cooking loss, L* and b* and n-6:n-3 ratio. Meat from 1/2-Angus presented greater a* than Limousin cross-breed. Whereas Angus had the highest total SFA content, Hereford had the lowest total SFA and the highest total MUFA. Limousin cross-breed had greater content of several individual PUFAs, total PUFA, n-6 and n-3 FA than Angus and 1/2-Angus. Leptin and FA synthase were associated with some FAs, supporting their influence over fat metabolism for grazing animals. Copyright © 2015 Elsevier Ltd. All rights reserved.

Probing Higgs self-coupling of a classically scale invariant model in e+e- → Zhh: Evaluation at physical point

NASA Astrophysics Data System (ADS)

Fujitani, Y.; Sumino, Y.

2018-04-01

A classically scale invariant extension of the standard model predicts large anomalous Higgs self-interactions. We compute missing contributions in previous studies for probing the Higgs triple coupling of a minimal model using the process e+e- → Zhh. Employing a proper order counting, we compute the total and differential cross sections at the leading order, which incorporate the one-loop corrections between zero external momenta and their physical values. Discovery/exclusion potential of a future e+e- collider for this model is estimated. We also find a unique feature in the momentum dependence of the Higgs triple vertex for this class of models.

Design of the Coordinate Transformation Function for Cylindrical Acoustic Cloaks with a Quantity of Discrete Layers

NASA Astrophysics Data System (ADS)

Cai, Li; Wen, Ji-Hong; Yu, Dian-Long; Lu, Zhi-Miao; Wen, Xi-Sen

2014-09-01

Acoustic cloak based on coordinate transformation is of great topical interest and has promise in potential applications such as sound transparency and insulation. The frequency response of acoustic cloaks with a quantity of discrete homogeneous layers is analyzed by the acoustic scattering theory. The effect of coordinate transformation function on the acoustic total scattering cross section is discussed to achieve low scattering with only a few layers of anisotropic metamaterials. Also, the physics of acoustic wave interaction with the interfaces between the discrete layers inside the cloak shell is discussed. These results provide a better way of designing a multilayered acoustic cloak with fewer layers.

Interactions of relativistic neon to nickel projectiles in hydrogen, elemental production cross sections

NASA Astrophysics Data System (ADS)

Knott, C. N.; Albergo, S.; Caccia, Z.; Chen, C.-X.; Costa, S.; Crawford, H. J.; Cronqvist, M.; Engelage, J.; Ferrando, P.; Fonte, R.; Greiner, L.; Guzik, T. G.; Insolia, A.; Jones, F. C.; Lindstrom, P. J.; Mitchell, J. W.; Potenza, R.; Romanski, J.; Russo, G. V.; Soutoul, A.; Testard, O.; Tull, C. E.; Tuvé, C.; Waddington, C. J.; Webber, W. R.; Wefel, J. P.

1996-01-01

This paper reports the elemental production cross sections for 17 projectile-energy combinations with energies between 338 and 894 MeV/nucleon interacting in a liquid hydrogen target. These results were obtained from two runs at the LBL Bevalac using projectiles ranging from 22Ne to 58Ni. Cross sections were measured for all fragment elements with charges greater than or equal to half the charge of the projectile. The results show that, over the energy and ion range investigated, the general decrease in cross section with decreasing fragment charge is strongly modified by the isospin of the projectile ion. Significant additional modifications of the cross sections due to the internal structure of the nucleus have also been seen. These include both pairing and shell effects. Differences in the cross sections due to the differing energies of the projectile are also considerable.

Cross dimerization of amyloid-β and αsynuclein proteins in aqueous environment: a molecular dynamics simulations study.

PubMed

Jose, Jaya C; Chatterjee, Prathit; Sengupta, Neelanjana

2014-01-01

Self-assembly of the intrinsically unstructured proteins, amyloid beta (Aβ) and alpha synclein (αSyn), are associated with Alzheimer's Disease, and Parkinson's and Lewy Body Diseases, respectively. Importantly, pathological overlaps between these neurodegenerative diseases, and the possibilities of interactions between Aβ and αSyn in biological milieu emerge from several recent clinical reports and in vitro studies. Nevertheless, there are very few molecular level studies that have probed the nature of spontaneous interactions between these two sequentially dissimilar proteins and key characteristics of the resulting cross complexes. In this study, we have used atomistic molecular dynamics simulations to probe the possibility of cross dimerization between αSyn1-95 and Aβ1-42, and thereby gain insights into their plausible early assembly pathways in aqueous environment. Our analyses indicate a strong probability of association between the two sequences, with inter-protein attractive electrostatic interactions playing dominant roles. Principal component analysis revealed significant heterogeneity in the strength and nature of the associations in the key interaction modes. In most, the interactions of repeating Lys residues, mainly in the imperfect repeats 'KTKEGV' present in αSyn1-95 were found to be essential for cross interactions and formation of inter-protein salt bridges. Additionally, a hydrophobicity driven interaction mode devoid of salt bridges, where the non-amyloid component (NAC) region of αSyn1-95 came in contact with the hydrophobic core of Aβ1-42 was observed. The existence of such hetero complexes, and therefore hetero assembly pathways may lead to polymorphic aggregates with variations in pathological attributes. Our results provide a perspective on development of therapeutic strategies for preventing pathogenic interactions between these proteins.

Pharmaceutical industry interactions of psychiatric trainees from 20 European countries.

PubMed

Riese, F; Guloksuz, S; Roventa, C; Fair, J D; Haravuori, H; Rolko, T; Flynn, D; Giacco, D; Banjac, V; Jovanovic, N; Bayat, N; Palumbo, C; Rusaka, M; Kilic, O; Augėnaitė, J; Nawka, A; Zenger, M; Kekin, I; Wuyts, P; Barrett, E; Bausch-Becker, N; Mikaliūnas, J; Del Valle, E; Feffer, K; Lomax, G A; Marques, J G; Jauhar, S

2015-02-01

Interactions between the pharmaceutical industry (PI) and psychiatrists have been under scrutiny recently, though there is little empirical evidence on the nature of the relationship and its intensity at psychiatry trainee level. We therefore studied the level of PI interactions and the underlying beliefs and attitudes in a large sample of European psychiatric trainees. One thousand four hundred and forty-four psychiatric trainees in 20 European countries were assessed cross-sectionally, with a 62-item questionnaire. The total number of PI interactions in the preceding two months varied between countries, with least interactions in The Netherlands (M (Mean)=0.92, SD=1.44, range=0-12) and most in Portugal (M=19.06, SD=17.44, range=0-100). Trainees were more likely to believe that PI interactions have no impact on their own prescribing behaviour than that of other physicians (M=3.30, SD=1.26 vs. M=2.39, SD=1.06 on a 5-point Likert scale: 1 "completely disagree" to 5 "completely agree"). Assigning an educational role to the pharmaceutical industry was associated with more interactions and higher gift value (IRR (incidence rate ratio)=1.21, 95%CI=1.12-1.30 and OR=1.18, 95%CI=1.02-1.37). There are frequent interactions between European psychiatric trainees and the PI, with significant variation between countries. We identified several factors affecting this interaction, including attribution of an educational role to the PI. Creating alternative educational opportunities and specific training dedicated to PI interactions may therefore help to reduce the impact of the PI on psychiatric training. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Inclusive neutrino scattering off the deuteron from threshold to GeV energies

NASA Astrophysics Data System (ADS)

Shen, G.; Marcucci, L. E.; Carlson, J.; Gandolfi, S.; Schiavilla, R.

2012-09-01

Background: Neutrino-nucleus quasi-elastic scattering is crucial to interpret the neutrino oscillation results in long baseline neutrino experiments. There are rather large uncertainties in the cross section, due to insufficient knowledge on the role of two-body weak currents.Purpose: Determine the role of two-body weak currents in neutrino-deuteron quasi-elastic scattering up to GeV energies.Methods: Calculate cross sections for inclusive neutrino scattering off deuteron induced by neutral and charge-changing weak currents, from threshold up to GeV energies, using the Argonne v18 potential and consistent nuclear electroweak currents with one- and two-body terms.Results: Two-body contributions are found to be small, and increase the cross sections obtained with one-body currents by less than 10% over the whole range of energies. Total cross sections obtained by describing the final two-nucleon states with plane waves differ negligibly, for neutrino energies ≳ MeV, from those in which interaction effects in these states are fully accounted for. The sensitivity of the calculated cross sections to different models for the two-nucleon potential and/or two-body terms in the weak current is found to be weak. Comparing cross sections to those obtained in a naive model in which the deuteron is taken to consist of a free proton and neutron at rest, nuclear structure effects are illustrated to be non-negligible.Conclusion: Contributions of two-body currents in neutrino-deuteron quasi-elastic scattering up to GeV are found to be smaller than 10%. Finally, it should be stressed that the results reported in this work do not include pion production channels.

A dependence of quasielastic charged-current neutrino-nucleus cross sections

NASA Astrophysics Data System (ADS)

Van Dessel, N.; Jachowicz, N.; González-Jiménez, R.; Pandey, V.; Van Cuyck, T.

2018-04-01

Background: 12C has been and is still widely used in neutrino-nucleus scattering and oscillation experiments. More recently, 40Ar has emerged as an important nuclear target for current and future experiments. Liquid argon time projection chambers (LArTPCs) possess various advantages in measuring electroweak neutrino-nucleus cross sections. Concurrent theoretical research is an evident necessity. Purpose: 40Ar is larger than 12C , and one expects nuclear effects to play a bigger role in reactions. We present inclusive differential and total cross section results for charged-current neutrino scattering on 40Ar and perform a comparison with 12C , 16O , and 56Fe targets, to find out about the A -dependent behavior of model predictions. Method: Our model starts off with a Hartree-Fock description of the nucleus, with the nucleons interacting through a mean field generated by an effective Skyrme force. Long-range correlations are introduced by means of a continuum random phase approximation approach. Further methods to improve the accuracy of model predictions are also incorporated in the calculations. Results: We present calculations for 12C , 16O , 40Ar , and 56Fe , showcasing differential cross sections over a broad range of kinematic values in the quasielastic regime. We furthermore show flux-folded results for 40Ar and we discuss the differences between nuclear responses. Conclusions: At low incoming energies and forward scattering we identify an enhancement in the 40Ar cross section compared to 12C , as well as in the high ω (low Tμ) region across the entire studied Eν range. The contribution to the folded cross section of the reaction strength at values of ω lower than 50 MeV for forward scattering is sizable.