Prognostic significance of obstructive uropathy in advanced prostate cancer.

PubMed

Oefelein, Michael G

2004-06-01

To report the incidence and prognostic implications of obstructive uropathy (OU) in patients with advanced prostate cancer receiving androgen deprivation therapy and to define the impact initial local therapy has on the development of OU in patients with prostate cancer who develop recurrence and begin androgen deprivation therapy. From a population of 260 patients with advanced prostate cancer diagnosed between 1986 and 2003, OU was identified in 51 patients. The OU treatment options included ureteral stent, percutaneous nephrostomy, transurethral resection of the prostate, Foley catheter placement, and urinary diversion. Overall survival and the factors that influenced survival were calculated using standard statistical methods. OU was diagnosed in 15 (16%) of 80 patients who received local therapy with curative intent and in whom local therapy subsequently failed and in 36 (19%) of 180 patients who had never received local therapy (P = 0.7, chi-square test). Of these 51 patients, 39 had bladder neck obstruction and 16 had ureteral obstruction. Overall survival was significantly worse for the men with OU compared with those without OU (41 versus 54 months). OU was associated with tumor stage and androgen-insensitive prostate cancer. OU results in significantly reduced survival in men with prostate cancer. In a select group of patients with prostate cancer with progression after local therapy (primarily radiotherapy), no statistically significant reduction in the development of OU was observed relative to patients matched for stage, grade, and pretreatment prostate-specific antigen level treated with androgen deprivation therapy alone. Aggressive advanced stage and hormone-insensitive disease are variables associated with OU.

[Post-lasik corneal ectasia in patients with significant differences in keratometry readings between both eyes].

PubMed

Ortega-Usobiaga, J; Llovet-Osuna, F; Djodeyre, M R; Llovet-Rausell, A; Beltran-Sanz, J; Baviera-Sabater, J

2014-03-01

A study is made on the incidence of corneal ectasia after laser in situ keratomileusis (LASIK) in patients with large differences in mean keratometry (MK) readings between both eyes (OU). Visual outcomes were also evaluated. The medical records of 164,603 patients (315,259 eyes) who underwent LASIK from January 2003 to December 2011 were reviewed in order to identify patients with a difference in MK of ≥ 1.25 D between OU. The main outcome measures were incidence of ectasia after LASIK, and visual outcome. A total of 35 eyes that met the inclusion criteria were found. Functional and visual results were those expected for myopia studies. After a minimum follow-up of 2 years, no corneal ectasia was found in 3 eyes (2 patients). The possibility of finding a patient with an asymmetry in MK and normal topography is low (0.021%), and it does not seem to be a contraindication of LASIK. Although no corneal ectasia was found in this case series, and as it is a potentially sight-threatening complication, patients with very different MK between OU should be studied carefully before undergoing LASIK. Copyright © 2013 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.

Determination of the origin of elevated uranium at a Former Air Force Landfill using non-parametric statistics analysis and uranium isotope ratio analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weismann, J.; Young, C.; Masciulli, S.

2007-07-01

Lowry Air Force Base (Lowry) was closed in September 1994 as part of the Base Realignment and Closure (BRAC) program and the base was transferred to the Lowry Redevelopment Authority in 1995. As part of the due diligence activities conducted by the Air Force, a series of remedial investigations were conducted across the base. A closed waste landfill, designated Operable Unit 2 (OU 2), was initially assessed in a 1990 Remedial Investigation (RI; [1]). A Supplemental Remedial Investigation was conducted in 1995 [2] and additional studies were conducted in a 1998 Focused Feasibility Study. [3] The three studies indicated thatmore » gross alpha, gross beta, and uranium concentrations were consistently above regulatory standards and that there were detections of low concentrations other radionuclides. Results from previous investigations at OU 2 have shown elevated gross alpha, gross beta, and uranium concentrations in groundwater, surface water, and sediments. The US Air Force has sought to understand the provenance of these radionuclides in order to determine if they could be due to leachates from buried radioactive materials within the landfill or whether they are naturally-occurring. The Air Force and regulators agreed to use a one-year monitoring and sampling program to seek to explain the origins of the radionuclides. Over the course of the one-year program, dissolved uranium levels greater than the 30 {mu}g/L Maximum Contaminant Level (MCL) were consistently found in both up-gradient and down-gradient wells at OU 2. Elevated Gross Alpha and Gross Beta measurements that were observed during prior investigations and confirmed during the LTM were found to correlate with high dissolved uranium content in groundwater. If Gross Alpha values are corrected to exclude uranium and radon contributions in accordance with US EPA guidance, then the 15 pCi/L gross alpha level is not exceeded. The large dataset also allowed development of gross alpha to total uranium correlation factors so that gross alpha action levels can be applied to future long-term landfill monitoring to track radiological conditions at lower cost. Ratios of isotopic uranium results were calculated to test whether the elevated uranium displayed signatures indicative of military use. Results of all ratio testing strongly supports the conclusion that the uranium found in groundwater, surface water, and sediment at OU 2 is naturally-occurring and has not undergone anthropogenic enrichment or processing. U-234:U-238 ratios also show that a disequilibrium state, i.e., ratio greater than 1, exists throughout OU 2 which is indicative of long-term aqueous transport in aged aquifers. These results all support the conclusion that the elevated uranium observed at OU 2 is due to the high concentrations in the regional watershed. Based on the results of this monitoring program, we concluded that the elevated uranium concentrations measured in OU 2 groundwater, surface water, and sediment are due to the naturally-occurring uranium content of the regional watershed and are not the result of waste burials in the former landfill. Several lines of evidence indicate that natural uranium has been naturally concentrated beneath OU 2 in the geologic past and the higher of uranium concentrations in down-gradient wells is the result of geochemical processes and not the result of a uranium ore disposal. These results therefore provide the data necessary to support radiological closure of OU 2. (authors)« less

Accuracy of enhanced and unenhanced MRI in diagnosing scaphoid proximal pole avascular necrosis and predicting surgical outcome.

PubMed

Fox, M G; Wang, D T; Chhabra, A B

2015-11-01

Determine the sensitivity, specificity and accuracy of unenhanced and enhanced MRI in diagnosing scaphoid proximal pole (PP) avascular necrosis (AVN) and correlate whether MRI can help guide the selection of a vascularized or nonvascularized bone graft. The study was approved by the IRB. Two MSK radiologists independently performed a retrospective review of unenhanced and enhanced MRIs from 18 patients (16 males, 2 females; median age, 17.5 years) with scaphoid nonunions and surgery performed within 65 days of the MRI. AVN was diagnosed on the unenhanced MRI when a diffusely decreased T1-W signal was present in the PP and on the enhanced MRI when PP enhancement was less than distal pole enhancement. Surgical absence of PP bleeding was diagnostic of PP AVN. Postoperative osseous union (OU) was assessed with computed tomography and/or radiographs. Sensitivity, specificity and accuracy for PP AVN were 71, 82 and 78% for unenhanced and 43, 82 and 67% for enhanced MRI. Patients with PP AVN on unenhanced MRI had 86% (6/7) OU; 100% (5/5) OU with vascularized bone grafts and 50% (1/2) OU with nonvascularized grafts. Patients with PP AVN on enhanced MRI had 80% (4/5) OU; 100% (3/3) OU with vascularized bone grafts and 50% (1/2) OU with nonvascularized grafts. Patients with viable PP on unenhanced and enhanced MRI had 91% (10/11) and 92% (12/13) OU, respectively, all but one with nonvascularized graft. When PP AVN is evident on MRI, OU is best achieved with vascularized grafts. If PP AVN is absent, OU is successful with nonvascularized grafts.

Gravity Effects in Small-Scale Structural Modeling

DTIC Science & Technology

1988-12-01

attenuating material (Reference 23). The materials tested were cellular concrete with fly ash, expanded polystyrene concrete with fly ash, foamed...polyurethane, foamed sulfer and molded expanded polystyrene . The studies showed that with proper adjustments in the cement content, water-cement ratio and foam...Compression (Ou,c) 4000 100 Tension (Ou,t) 400 10 E/Quc 1000 1000 Ou,c/Ou,t 10 10 Further analysis of the properties of expanded polystyrene concrete with

Unexpected Hospitalisations at a 23-Hour Observation Unit in a Paediatric Emergency Department of Northern India

PubMed Central

Mahajan, Vidushi; Arora, Sumant; Kaur, Tarundeep; Gupta, Sorab; Guglani, Vishal

2013-01-01

Background: The 23-hour Observation Unit (OU) is a novel and an effective means for tackling overcrowding in busy Paediatric Emergency Departments (PED) worldwide. However, unexpected hospitalisations in the OU involve transfer of care and they reduce the efficiency of the OU. Hence, we aimed to study the presenting diagnoses which were responsible for the unexpected hospitalisations in a 23-hour OU. Methods and Design: A prospective cohort study Setting: The PED at a tertiary care teaching hospital. Duration: 15th Feb-15th March 2011. Protocol: Consecutive children were triaged at presentation to the PED, according to the WHO paediatric emergency triage algorithm. Those who were transferred to the 23-hour OU, were further followed up for duration of the stay, the hospital course, and the outcome (discharge/hospitalisation). Results: Three hundred (228 males, 72 females) consecutive children who attended the PED over one month were enrolled. All the children, at presentation, were triaged by the medical intern/s who was/were posted in the PED, and they were crosschecked by a PED consultant. A majority (55%, n=165) of the children were triaged as non-urgent, 32% (n=97) as priority and 13% (n=38) as emergent. Out of the 300 children, 173(58%) were transferred to the 23-hour OU. Of these, 16 (9.1%) required unexpected hospitalisations. The children who required hospitalisations had the following diagnoses: bronchiolitis (4), bronchopneumonia (4), seizure (2), viral hepatitis (2), high fever (1), bronchial asthma (1), severe anaemia (1), and urticaria (1). The mean duration of the stay in the OU was 19 hours for those who needed hospitalisation, as against 13 hours for those who were discharged from the OU. Conclusion: The children with respiratory complaints (bronchiolitis and bronchopneumonia) need frequent monitoring in the 23-hour OU, as they have high hospitalisation rates in the OU. PMID:23998079

[The Summer School of the German Society for Orthopaedics and Traumatology - A Success Story].

PubMed

Merschin, D; Mutschler, M; Stange, R; Kopschina, C; Schüttrumpf, J P; Doepfer, A K; Achatz, G; Niethard, M; Hoffmann, R; Kladny, B; Perl, M; Münzberg, M

2016-10-01

Background: It has been known for several years that orthopaedic and trauma clinics suffer from a shortage of young people, due to the substantial loss in attractiveness. The Youth Forum OU has been addressing this problem for many years, by initiating many projects such as the Summer School to counteract this trend. The purpose of this research is to evaluate the success of Summer Schools since 2009. Methods: The Youth Forum OU performed a survey in December 2014 to answer the research question on the basis of an internet-based poll of the student participants in all Summer Schools between 2009 and 2014. Following data cleansing, 121 students and former students were included in the survey. Results: Seventy-two completed questionnaires were collected and included in the evaluation. The survey included 40 % of Summer School participants, with a mean age of 27.3 years (SD ± 2.95); 50 % were female. Participation in the Summer School helped 50 % of the respondents to decide to start advanced study in orthopaedics and/or traumatology (OU). One third of these Summer School participants had already finished a university degree; 100 % are now residents in orthopaedics and/or traumatology. Regardless of prior plans, 87.2 % of participants are now residents in OU. Thirty-three are still students: 78.8 % have already decided to work in OU. The survey also served to identify the factors positively and negatively associated with OU. Unfavourable factors included the reputation of OU, and the difficulty of reconciling family and work. Favourable factors included surgical work and personal experience during university studies. Discussion: The aim of this study was to evaluate whether the efforts of the Youth Forum OU, the German Society for Orthopaedics and Traumatology (DGOU) and the local hospitals lead to increased interest in OU. The answer to this question is positive. This is particularly true for those students who did not plan to become an orthopaedic or trauma surgeon before participating in a Summer School. In conclusion, the efforts to recruit residents for OU by using Summer Schools were successful. Moreover, this research offers approaches to counteract the loss of attractiveness of OU. Georg Thieme Verlag KG Stuttgart · New York.

Analysis of Aquifer Response, Groundwater Flow, and PlumeEvolution at Site OU 1, Former Fort Ord, California

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jordan, Preston D.; Oldenburg, Curtis M.; Su, Grace W.

2005-02-24

This report presents a continuation from Oldenburg et al. (2002) of analysis of the hydrogeology, In-Situ Permeable Flow Sensor (ISPFS) results, aquifer response, and changes in the trichloroethylene (TCE) groundwater plume at Operational Unit 1 (OU 1) adjacent to the former Fritzsche Army Airfield at the former Fort Ord Army Base, located on Monterey Bay in northern Monterey County. Fuels and solvents were burned on a portion of OU 1 called the Fire Drill Area (FDA) during airport fire suppression training between 1962 and 1985. This activity resulted in soil and groundwater contamination in the unconfined A-aquifer. In the latemore » 1980's, soil excavation and bioremediation were successful in remediating soil contamination at the site. Shortly thereafter, a groundwater pump, treat, and recharge system commenced operation. This system has been largely successful at remediating groundwater contamination at the head of the groundwater plume. However, a trichloroethylene (TCE) groundwater plume extends approximately 3000 ft (900 m) to the northwest away from the FDA. In the analyses presented here, we augment our prior work (Oldenburg et al., 2002) with new information including treatment-system totalizer data, recent water-level and chemistry data, and data collected from new wells to discern trends in contaminant migration and groundwater flow that may be useful for ongoing remediation efforts. Some conclusions from the prior study have been modified based on these new analyses, and these are pointed out clearly in this report.« less

Understanding and Assessing Risk of Intrastate Conflict: Human Development Theory and Practice

DTIC Science & Technology

2004-04-01

R es ou rc es O pp or tu ni ty S ec ur ity V io le nc e Le ve l To ta l R is k R es...ou rc es O pp or tu ni ty S ec ur ity V io le nc e Le ve l To ta l R is k R es ou rc es O pp or tu ni ty S ec ur ity V io le nc e Le ve...l To ta l R is k R es ou rc es O pp or

Online Library Accessibility Support: A Case Study within the Open University Library

ERIC Educational Resources Information Center

Mears, Wendy; Clough, Helen

2015-01-01

The Open University (OU) is the UK's largest distance education provider and has a large and growing disabled student population. Disabled user support presents particular challenges for an online library service in the distance learning environment. The OU introduced guidelines for working with non-OU--authored content (external content) in 2011…

77 FR 64748 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-23

... Sands Tailings parcel of Operable Unit 1 (OU1) of the Torch Lake Superfund Site (Site), located in... Michigan through the Michigan Department of Environmental Quality (MDEQ), because EPA has determined that... parcels of OU3 and the Mason Sands Tailings parcel of OU1. The following land parcels will remain on the...

Something for Everyone? The Different Approaches of Academic Disciplines to Open Educational Resources and the Effect on Widening Participation

ERIC Educational Resources Information Center

Coughlan, Tony; Perryman, Leigh-Anne

2011-01-01

This article explores the relationship between academic disciplines' representation in the United Kingdom Open University's (OU) OpenLearn open educational resources (OER) repository and in the OU's fee-paying curriculum. Becher's (1989) typology was used to subdivide the OpenLearn and OU fee-paying curriculum content into four disciplinary…

The Legacy and Impact of Open University Women's/Gender Studies: 30 Years On

ERIC Educational Resources Information Center

Kirkup, Gill; Whitelegg, Elizabeth

2013-01-01

In 1983, the UK Open University (OU) offered its first women's/gender studies (WGS) course. Although a late entrant to the area, OU WGS courses were influential nationally and internationally for many feminists and WGS teachers and scholars. Not only did OU WGS courses have the largest WGS student cohort of any UK institution with over 8000…

Cooperation or Competition? The American and French Foreign Policies in Africa (Cooperation ou concurrence? La politique africaine de la France et des Etats-Unis en Afrique sub-saharienne)

DTIC Science & Technology

2005-07-26

Villepin, appelle « des conflits ancestraux >>, c’est-di-dire des conflits pour le contr6le de ressources primaires , ou de territoire, ou pour des diff~rends...traduira par une plus grande attention portde aux sujets africains et aussi d la part du budget pour l’Afrique. Le facteur religieux Les missionnaires en...grands avions de transport ou celles des soldats 6tablissant des centres de soins m6dicaux avec les ONG. Comme Jean-Paul Ngoupand6 l’a exprim6: << On

Modelling of Ionospheric Irregularities and Total Electron Content.

DTIC Science & Technology

1983-12-01

jApproved for public release; distribution unlimited DTIC SELECTEd MAY2 11 84 AIR FORCE GEOPHYSICS LABORATORY B C3 AIR FORCE SYSTEMS COMMAND .. UNITED...DOWNGRADING 16. OISTRIBUTION STATEMENT (of this Rerport) Approved for Public Release; Distribution Unlimited 1?. DISTRIBUTION STATEMENT (o1 .he obrfoct...Space Division, Project 2029, and the Air Force Office of Scientific Research, Task 2311G2. 19. KEY WORDS (CO1ir oU ngooe I ,-- . 1d -d0n~ Id-nWI A

Thule AB, Greenland. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F.

DTIC Science & Technology

1981-12-18

7! USAFETAC PORn 0--5 (OL-A) PSIViOUS lIOWstO Of t$is Foam Am OU8O&IN * AA Ř L’~ C L AT C L,) C T I - :SURFACE WINDS V ~ PERCENTAGE FREQUENCY OF WIND...93. 93. 95. 96 1 96* 97. . 97 5 97 5 98.8 98:8 99 .2 L00 .3 TOTAL NUMBER OF OBSERVATIONS 81 USAF STAC : 0-14-9 (a A) V hD .... b

Wave Data Acquisition and Hindcast for Saginaw Bay, Michigan.

DTIC Science & Technology

1983-06-01

Bretschneider (1952) and Mitsuyasu and Kimura (1965) for f the peak fre- %m quency (where fm = f g/U) while the total energy decay rate follows that mm...Spectra of Wind-Generated Gravity Waves," Journal of Physical Oceanography, Vol 5, pp 410-420. Mitsuyasu, Hisashi . 1968. "On the Growth of the...8217 . , / . - . ’ -’ -. .. ’ . .. _..- -’ - Mitsuyasu, Hisashi , and Kirmura, Hisao. 1965. "Wind Wave in Decay Area," Coastal Engineering in Japan, Vol 8, pp 221-35. Ou, Shan-Hwei. 1980 (Sep

Human Factors Aspects of Aircraft Accidents

DTIC Science & Technology

1982-10-01

preexistante (incapacite soudaine ou non en vo_l) La plus dangereuse (en particulier dans les phases decollage et atterrissage) est l’in- capacite... soudaine . Elle peut 6tre mortelle - dans ce caa, generalement eardiaque - ou sa traduire par des troubles psychiques - d’un developpement brutal et...done conduire a une lncapacite plus ou moins soudaine en vol. pefaillances physiques accidentelles Kors les defaillances physiques classiques

Operable Unit B1 Interim Record of Decision. Installation Restoration Program (IRP)

DTIC Science & Technology

1993-07-28

Geology ..................................... I-1 2.0 SITE HISTORY AND ENFORCEMENT ACTIVITIES ........... 11-5 2.1 Background on Contamination Problems at...McClellan AFB OU BI . 11-5 2.2 Previous Studies ................................ 11-5 2.3 Regulatory and Enforcement History .................... 11-7...1-4 2-1 History of OU BI ...................................... 11-6 4-1 Cross-Section A-A’ of OU B.I

Verifying entanglement in the Hong-Ou-Mandel dip

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ray, Megan R.; Enk, S. J. van

2011-04-15

The Hong-Ou-Mandel interference dip is caused by an entangled state, a delocalized biphoton state. We propose a method of detecting this entanglement by utilizing inverse Hong-Ou-Mandel interference, while taking into account vacuum and multiphoton contaminations, phase noise, and other imperfections. The method uses just linear optics and photodetectors, and for single-mode photodetectors we find a lower bound on the amount of entanglement.

Occlusal Support and Temporomandibular Disorders Among Elderly Vietnamese.

PubMed

Nguyen, Minh Son; Jagomägi, Triin; Nguyen, Toai; Saag, Mare; Voog-Oras, Ülle

The aim of this study was to analyze the associations between missing teeth, occlusal support, and temporomandibular disorders (TMD) among elderly Vietnamese. The study consisted of 145 TMD and 112 non-TMD (control group) participants aged 65 to 74 years. TMD was evaluated using Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) Axis I. An occlusal unit (OU) was defined as the cusp of a tooth coupled with the fossa of its antagonist tooth. A premolar pair was counted as one OU and a molar pair as two OUs. Dentition was divided into four occlusal support zones (OSZs) based on occluding pairs of posterior teeth by using Eichner classification: Class A had 4 OSZs, Class B had 1 to 3 OSZs or only anterior teeth, and Class C had no OSZ. The TMD group lost significantly more posterior teeth (mean ± SD 5.1 ± 4.7) than the control group (4.0 ± 3.9, P = .033). The mean ± SD OUs of the TMD and control groups were 5.1 ± 4.6 and 6.0 ± 4.3, respectively, which was nonsignificant (NS). The distribution of Class A (40.7%), Class B (40.0%), and Class C (19.3%) among the TMD group was not significantly different from the control group (50.0%, 38.4%, and 11.6%, respectively, NS). The odds of having TMD were positively associated with total unilateral loss of OUs (OR = 3.4, 95% CI = 1.2-9.4, P = .020) and total bilateral loss of OUs (OR = 2.7, 95% CI = 1.2-6.6, P = .027). Total loss of OSZs on one or both sides of the mouth were found to be predictors of TMD among elderly Vietnamese.

Nitrogen effects on proteins, chlorophylls and fatty acids during the growth of Arthrospira platensis.

PubMed

Ayachi, Samah; El Abed, Amor; Dhifi, Wissal; Marzouk, Brahim

2007-06-01

Spirulina platensis (=Arthrospira platensis) is a tunisian strain which has been isolated for the first time in Oued Essed (Sousse, Sidi Bou Ali). Biomass evolution, proteins, chlorophylls and fatty acids composition of this alga were monitored by varying nitrogen concentrations in the culture medium. Nitrogen stress was provoked by adding sodium nitrate (NaNO3) in the culture medium with concentrations varying from 0 to 5 g/l. Results obtained showed that nitrogen depletion increased total proteins and total chlorophylls. The addition of NaNO3 (5g/l) led to an increase of total fatty acids amounts and modify fatty acids composition. Optimal quantities of palmitic, gamma -linolenic and oleic acids were obtained with NaNO3 free-cultures. Thus, the tunisian strain has valuable biological substances, worthy to determine the optimal conditions for its propagation.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sobolewska, M. A.; Siemiginowska, A.; Kelly, B. C.

We study the γ-ray variability of 13 blazars observed with the Fermi/Large Area Telescope (LAT). These blazars have the most complete light curves collected during the first four years of the Fermi sky survey. We model them with the Ornstein-Uhlenbeck (OU) process or a mixture of the OU processes. The OU process has power spectral density (PSD) proportional to 1/f {sup α} with α changing at a characteristic timescale, τ{sub 0}, from 0 (τ >> τ{sub 0}) to 2 (τ << τ{sub 0}). The PSD of the mixed OU process has two characteristic timescales and an additional intermediate region withmore » 0 < α < 2. We show that the OU model provides a good description of the Fermi/LAT light curves of three blazars in our sample. For the first time, we constrain a characteristic γ-ray timescale of variability in two BL Lac sources, 3C 66A and PKS 2155-304 (τ{sub 0} ≅ 25 days and τ{sub 0} ≅ 43 days, respectively, in the observer's frame), which are longer than the soft X-ray timescales detected in blazars and Seyfert galaxies. We find that the mixed OU process approximates the light curves of the remaining 10 blazars better than the OU process. We derive limits on their long and short characteristic timescales, and infer that their Fermi/LAT PSD resemble power-law functions. We constrain the PSD slopes for all but one source in the sample. We find hints for sub-hour Fermi/LAT variability in four flat spectrum radio quasars. We discuss the implications of our results for theoretical models of blazar variability.« less

Performance of the dipstick screening test as a predictor of negative urine culture.

PubMed

Marques, Alexandre Gimenes; Doi, André Mario; Pasternak, Jacyr; Damascena, Márcio Dos Santos; França, Carolina Nunes; Martino, Marinês Dalla Valle

2017-01-01

To investigate whether the urine dipstick screening test can be used to predict urine culture results. A retrospective study conducted between January and December 2014 based on data from 8,587 patients with a medical order for urine dipstick test, urine sediment analysis and urine culture. Sensitivity, specificity, positive and negative predictive values were determined and ROC curve analysis was performed. The percentage of positive cultures was 17.5%. Nitrite had 28% sensitivity and 99% specificity, with positive and negative predictive values of 89% and 87%, respectively. Leukocyte esterase had 79% sensitivity and 84% specificity, with positive and negative predictive values of 51% and 95%, respectively. The combination of positive nitrite or positive leukocyte esterase tests had 85% sensitivity and 84% specificity, with positive and negative predictive values of 53% and 96%, respectively. Positive urinary sediment (more than ten leukocytes per microliter) had 92% sensitivity and 71% specificity, with positive and negative predictive values of 40% and 98%, respectively. The combination of nitrite positive test and positive urinary sediment had 82% sensitivity and 99% specificity, with positive and negative predictive values of 91% and 98%, respectively. The combination of nitrite or leukocyte esterase positive tests and positive urinary sediment had the highest sensitivity (94%) and specificity (84%), with positive and negative predictive values of 58% and 99%, respectively. Based on ROC curve analysis, the best indicator of positive urine culture was the combination of positives leukocyte esterase or nitrite tests and positive urinary sediment, followed by positives leukocyte and nitrite tests, positive urinary sediment alone, positive leukocyte esterase test alone, positive nitrite test alone and finally association of positives nitrite and urinary sediment (AUC: 0.845, 0.844, 0.817, 0.814, 0.635 and 0.626, respectively). A negative urine culture can be predicted by negative dipstick test results. Therefore, this test may be a reliable predictor of negative urine culture. Verificar se a triagem de urina por fitas reativas é capaz de predizer a cultura de urina. Métodos Estudo retrospectivo realizado entre janeiro e dezembro de 2014 com 8.587 pacientes, com solicitação médica de triagem de urina (fita), sedimento urinário e cultura de urina. sensibilidade, especificidade, valor preditivo positivo, valor preditivo negativo e curva ROC. Foram positivas 17,5% das culturas. O nitrito apresentou sensibilidade de 28% e especificidade de 99%. O valor preditivo positivo foi de 89% e o valor preditivo negativo de 87%. Esterase apresentou sensibilidade de 79% e especificidade de 84%. Valor preditivo positivo e valor preditivo negativo foram de 51% e 95%, respectivamente. A combinação de nitrito ou esterase positivos apresentou sensibilidade de 85% e especificidade de 84%. Valor preditivo positivo e valor preditivo negativo foram, respectivamente, 53% e 96%. O sedimento positivo (mais de dez leucócitos por microlitro) apresentou sensibilidade de 92% e especificidade de 71%. O valor preditivo positivo foi 40% e o negativo, 98%. A combinação de nitrito e sedimento urinário positivos apresentou sensibilidade de 82% e especificidade de 99%. Os valores preditivos positivo e negativo foram 91% e 98%, respectivamente. Para o nitrito ou esterase positivos mais os leucócitos positivos, a sensibilidade foi de 94% e a especificidade de 84%. O valor preditivo positivo foi de 58% e o negativo foi de 99%. Com base na curva ROC, o melhor indicador de urocultura positiva foi a associação entre a esterase ou nitrito positivos na fita mais os leucócitos positivos no sedimento, seguido por nitrito e esterase positivos, sedimento urinário positivo isolado, esterase positiva isolada, nitrito positivo isolado e, finalmente, pela associação entre nitrito e sedimento urinário positivos (AUC: 0,845, 0,844, 0,817, 0,814, 0,635 e 0,626, respectivamente). Uma urocultura negativa pode ser prevista com resultados negativos na fita. Portanto, este teste pode ser um preditor confiável de urocultura negativa.

Superfund record of decision (EPA Region 3): Langley AFB/NASA Langley Center, Area E Warehouse Operable Unit, Hampton, VA, September 28, 1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-10-01

This Record of Decision (ROD) presents the selected remedial action for the Area E Warehouse Operable Unit (OU) at the NASA Langley Research Center (LaRC) in Hampton, Virginia (the Site). This actions addresses the principle threat at the OU by imposing land use restrictions that will prevent any non-industrial activities to take place on the OU.

Superfund record of decision (EPA Region 9): Mather Air Force Base, Soil and Groundwater operable units, Sacramento, CA, June 21, 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The decision document presents the selected remedial actions for the Soil Operable Unit (OU) Sites and Groundwater OU Plumes, at the formerly active Mather Air Force Base (AFB), Sacramento County, California. The purpose of the Record of Decision (ROD) is to decide the appropriate level of remediation necessary to protect human health and the environment, and determine what requirements are applicable or relevant and appropriate requirements (ARARs) based on the groundwater beneficial use designation and site-specific conditions. The ROD has been divided into seven sections which specifically address the range of selected remedial actions for the Soil OU sites andmore » Groundwater OU plumes.« less

Assessment of the quality of water by hierarchical cluster and variance analyses of the Koudiat Medouar Watershed, East Algeria

NASA Astrophysics Data System (ADS)

Tiri, Ammar; Lahbari, Noureddine; Boudoukha, Abderrahmane

2017-12-01

The assessment of surface water in Koudiat Medouar watershed is very important especially when it comes to pollution of the dam waters by discharges of wastewater from neighboring towns in Oued Timgad, who poured into the basin of the dam, and agricultural lands located along the Oued Reboa. To this end, the multivariable method was used to evaluate the spatial and temporal variation of the water surface quality of the Koudiat Medouar dam, eastern Algeria. The stiff diagram has identified two main hydrochemical facies. The first facies Mg-HCO3 is reflected in the first sampling station (Oued Reboa) and in the second one (Oued Timgad), while the second facies Mg-SO4 is reflected in the third station (Basin Dam). The results obtained by the analysis of variance show that in the three stations all parameters are significant, except for Na, K and HCO3 in the first station (Oued Reboa) and the EC in the second station (Oued Timgad) and at the end NO3 and pH in the third station (Basin Dam). Q-mode hierarchical cluster analysis showed that two main groups in each sampling station. The chemistry of major ions (Mg, Ca, HCO3 and SO4) within the three stations results from anthropogenic impacts and water-rock interaction sources.

Minnesota River at Chaska, Minnesota Flood Control Project. General Design Memorandum and Draft Supplement II to the Final Environmental Impact Statement. Revision.

DTIC Science & Technology

1984-08-01

Munesota. Flood Control Project (Geotechnical Cmmts). 2. Inclosed m ou resposes to the above-cited c ts. POt IT G0MVOAU: I Incl PC=U A. P13HR S Cdf...I . 4,! year period to house about 4b,O00 people in a self -contained community. Projections noted in the 1973 feasibility report were for a total...incorporation of trails for nature study, hiking, self -propelled bicycle, horseback riding, snowshoe, cross- country ski, and access by fishermen and

Hong-Ou-Mandel Interference Between Triggered And Heralded Single Photons From Separate Atomic Systems

NASA Astrophysics Data System (ADS)

Cere, Alessandro; Leong, Victor; Kaur Gulati, Gurpreet; Srivathsan, Bharath; Kosen, Sandoko; Kurtsiefer, Christian

2015-05-01

The realization of quantum networks and long distance quantum communication rely on the capability of generating entanglement between separated nodes. We demonstrate the compatibility of two different sources of single photons: a single atom and four-wave mixing in a cold cloud of atoms. The four-wave mixing process in a cloud of cold 87Rb generates photon pairs. The cascade level scheme used ensures the generation of heralded single photons with exponentially decaying temporal envelope. The temporal shape of the heralding photons matches the shape of photons emitted by spontaneous decay but for the shorter coherence time A single 87Rb atom is trapped in an far-off-resonance optical dipole trap and can be excited with high probability using a short (~3 ns) intense pulse of resonant light, emitting a single photon by spontaneous decay. A large numerical aperture lens collects ~4% of the total fluorescence. The heralded and the triggered photons are launched into a Houng-Ou-Mandel interferometer: a symmetrical beam-splitter with outputs connected to single photon detectors. Scanning the relative delay between the two sources we observe the HOM dip with a maximum visibility of 70 +/-4%.

Deterministic quantum splitter based on time-reversed Hong-Ou-Mandel interference

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Jun; Lee, Kim Fook; Kumar, Prem

2007-09-15

By utilizing a fiber-based indistinguishable photon-pair source in the 1.55 {mu}m telecommunications band [J. Chen et al., Opt. Lett. 31, 2798 (2006)], we present the first, to the best of our knowledge, deterministic quantum splitter based on the principle of time-reversed Hong-Ou-Mandel quantum interference. The deterministically separated identical photons' indistinguishability is then verified by using a conventional Hong-Ou-Mandel quantum interference, which exhibits a near-unity dip visibility of 94{+-}1%, making this quantum splitter useful for various quantum information processing applications.

Hong-Ou-Mandel interferometer with cavities: Theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Olindo, C.; Sagioro, M. A.; Monken, C. H.

2006-04-15

We study the number of coincidences in a Hong-Ou-Mandel interferometer exit whose arms have been supplemented with the addition of one or two optical cavities. The fourth-order correlation function at the beam splitter exit is calculated. In the regime where the cavities lengths are larger than the one-photon coherence length, photon coalescence and anticoalescence interference is observed. Feynman's path diagrams for the indistinguishable processes that lead to quantum interference are presented. The construction of an optical XOR gate is discussed as an application for the Hong-Ou-Mandel interferometer with two cavities.

Occupational hygiene in a Finnish drum composting plant.

PubMed

Tolvanen, Outi; Nykänen, Jenni; Nivukoski, Ulla; Himanen, Marina; Veijanen, Anja; Hänninen, Kari

2005-01-01

Bioaerosols (microbes, dust and endotoxins) and volatile organic compounds (VOCs) were determined in the working air of a drum composting plant treating source-separated catering waste. Different composting activities at the Oulu drum composting plant take place in their own units separated by modular design and constructions. Important implication of this is that the control room is a relatively clean working environment and the risk of exposure to harmful factors is low. However, the number of viable airborne microbes was high both in the biowaste receiving hall and in the drum composting hall. The concentration (geometric average) of total microbes was 21.8 million pcs/m3 in the biowaste receiving hall, 13.9 million pcs/m3 in the drum composting hall, and just 1.4 million pcs/m3 in the control room. Endotoxin concentrations were high in the biowaste receiving hall and in the drum composting hall. The average (arithmetic) endotoxin concentration was over the threshold value of 200 EU/m3 in both measurement locations. In all working areas, the average (arithmetic) dust concentrations were in a low range of 0.6-0.7 mg/m3, being below the Finnish threshold value of 5 mg/m3. In the receiving hall and drum composting hall, the concentrations of airborne microbes and endotoxins may rise to levels hazardous to health during prolonged exposure. It is advisable to use a respirator mask (class P3) in these areas. Detected volatile organic compounds were typical compounds of composting plants: carboxylic acids and their esters, alcohols, ketones, aldehydes, and terpenes. Concentrations of VOCs were much lower than the Finnish threshold limit values (Finnish TLVs), many of the quantified compounds exceeded their threshold odour concentrations (TOCs). Primary health effects due VOCs were not presumable at these concentrations but unpleasant odours may cause secondary symptoms such as nausea and hypersensitivity reactions. This situation is typical of composting plants where the workers are exposed to dozens of VOCs simultaneously. The odour units (OU/m3) were measured using olfactometer. The numbers were 23,000 OU/m3 at the output end of the composting drum and 6300 OU/m3 in the exhaust pipe. Inside the composting hall, the number of odour units was 500 and 560 OU/m3.

Calculation of odour emissions from aircraft engines at Copenhagen Airport.

PubMed

Winther, Morten; Kousgaard, Uffe; Oxbøl, Arne

2006-07-31

In a new approach the odour emissions from aircraft engines at Copenhagen Airport are calculated using actual fuel flow and emission measurements (one main engine and one APU: Auxiliary Power Unit), odour panel results, engine specific data and aircraft operational data for seven busy days. The calculation principle assumes a linear relation between odour and HC emissions. Using a digitalisation of the aircraft movements in the airport area, the results are depicted on grid maps, clearly reflecting aircraft operational statistics as single flights or total activity during a whole day. The results clearly reflect the short-term temporal fluctuations of the emissions of odour (and exhaust gases). Aircraft operating at low engine thrust (taxiing, queuing and landing) have a total odour emission share of almost 98%, whereas the shares for the take off/climb out phases (2%) and APU usage (0.5%) are only marginal. In most hours of the day, the largest odour emissions occur, when the total amount of fuel burned during idle is high. However, significantly higher HC emissions for one specific engine cause considerable amounts of odour emissions during limited time periods. The experimentally derived odour emission factor of 57 OU/mg HC is within the range of 23 and 110 OU/mg HC used in other airport odour studies. The distribution of odour emission results between aircraft operational phases also correspond very well with the results for these other studies. The present study uses measurement data for a representative engine. However, the uncertainties become large when the experimental data is used to estimate the odour emissions for all aircraft engines. More experimental data is needed to increase inventory accuracy, and in terms of completeness it is recommended to make odour emission estimates also for engine start and the fuelling of aircraft at Copenhagen Airport in the future.

Hiedelberg AAF, Germany Revised Uniform Summary of Surface Weather Observations (RUSSWO) Parts A-F.

DTIC Science & Technology

1981-10-05

P’EE’i 10 Z6 -5 -4 Z - -2v -->2 - . I -l ’A --. 1. 5/16 0 NO CELIN -- 14.9 16.6 17.1 19.8 20*0 21.1 21.3 21.7 22.5 22.5 22.5 22.6 22.7 22.7 22.8 >_000...99.7100.0 00.0100.0100.0 00.000.0 cOo 0o. TOTAL NUMBER OF OBSERVATIONS 9 USAF "TAC ,W 64 0-14-5 (OL A) P.e .OU.. DION OF VNI FON ANN.. ...... . -r4 -A V

X-ray diving in the center of Sh2-129: looking for the driving source of Ou4

NASA Astrophysics Data System (ADS)

Grosso, Nicolas

2012-10-01

The outflow phenomenon is associated both with the early and the last phase of the stellar evolution. Recently, a unique bipolar outflow with an angular size of 1.2 degrees was discovered in the blister HII region Sh2-129. Ou4, nicknamed "The Giant Squid", is to our knowledge the bipolar outflow with the largest angular size ever found. We propose joint XMM-Newton/EPIC (35 ks) and Chandra/HRC-I (16 ks) observations to look for the driving source of Ou4 and to clarify the nature of this object.

Superfund record of decision (EPA Region 3): US Defense General Supply Center, Operable Unit 9, Chesterfield County, VA, September 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-09-01

The decision document presents the selected interim remedial action for Operable Unit 9 (OU9) at the Defense General Supply Center (DGSC) in Chesterfield County, Virginia near Richmond. OU9 pertains to groundwater beneath Area 50, the Open Storage Area (OSA), and the Naitonal Guard Area (NGA). This operable unit is the third of nine operable units that are currently being addressed at the DGSC. OU9 addresses interim treatment and containment of groundwater in the upper and lower aquifers beneath Area 50, the OSA, and the NGA.

Approche au diagnostic de la maladie cœliaque chez les patients ayant une faible densité minérale osseuse ou des fractures de fragilité

PubMed Central

Rios, Lorena P.; Khan, Aliya; Sultan, Muhammad; McAssey, Karen; Fouda, Mona A.; Armstrong, David

2013-01-01

Résumé Objectif Présenter aux cliniciens une mise à jour sur le diagnostic de la maladie cœliaque (MC), ainsi que des recommandations sur les indications de procéder au dépistage de la MC chez les patients présentant une faible densité minérale osseuse (DMO) ou des fractures de fragilité. Qualité des données Un groupe de travail multidisciplinaire a élaboré des questions cliniquement pertinentes relativement au diagnostic de la MC servant de fondement à une recherche documentaire dans les bases de données MEDLINE, EMBASE et CENTRAL (de janvier 2000 à janvier 2009) à l’aide des mots clés en anglais celiac disease, osteoporosis, osteopenia, low bone mass et fracture. Les ouvrages scientifiques existants comportent des études de niveaux I et II. Message principal La prévalence estimée de la MC asymptomatique est de 2 % à 3 % chez les personnes qui ont une faible DMO. Par ailleurs, un dépistage ciblé est recommandé pour les patients qui ont des T-scores de −1,0 ou moins à la colonne vertébrale ou aux hanches ou des antécédents de fractures de fragilité associées à des symptômes ou à des problèmes reliés à la MC, des antécédents familiaux de MC ou de bas niveaux de calcium urinaire, une insuffisance en vitamine D et des niveaux à la hausse d’hormones parathyroïdiennes en dépit d’un apport suffisant en calcium et en vitamine D. Le dépistage de la MC devrait se faire pendant que le sujet consomme un régime alimentaire contenant du gluten. On procède au dépistage initial par le dosage d’immunoglobuline (Ig) A antitransglutaminase en utilisant la transglutaminase tissulaire humaine recombinante ou une autre transglutaminase tissulaire, en association avec l’immunofluorescence des IgA anti-endomysium. Une biopsie du duodénum est nécessaire pour confirmer le diagnostic de la MC. Le typage des antigènes des leucocytes humains peut aider à confirmer ou à exclure le diagnostic de la MC dans les cas où la sérologie et l’histologie ne concordent pas. Le diagnostic définitif se fonde sur les caractéristiques cliniques, sérologiques et histologiques combinées à une réponse positive à une alimentation sans gluten.

The different origins of magnetic fields and activity in the Hertzsprung gap stars, OU Andromedae and 31 Comae

NASA Astrophysics Data System (ADS)

Borisova, A.; Aurière, M.; Petit, P.; Konstantinova-Antova, R.; Charbonnel, C.; Drake, N. A.

2016-06-01

Context. When crossing the Hertzsprung gap, intermediate-mass stars develop a convective envelope. Fast rotators on the main sequence, or Ap star descendants, are expected to become magnetic active subgiants during this evolutionary phase. Aims: We compare the surface magnetic fields and activity indicators of two active, fast rotating red giants with similar masses and spectral class but different rotation rates - OU And (Prot = 24.2 d) and 31 Com (Prot = 6.8 d) - to address the question of the origin of their magnetism and high activity. Methods: Observations were carried out with the Narval spectropolarimeter in 2008 and 2013. We used the least-squares deconvolution (LSD) technique to extract Stokes V and I profiles with high signal-to-noise ratio to detect Zeeman signatures of the magnetic field of the stars. We then provide Zeeman-Doppler imaging (ZDI), activity indicators monitoring, and a precise estimation of stellar parameters. We use state-of-the-art stellar evolutionary models, including rotation, to infer the evolutionary status of our giants, as well as their initial rotation velocity on the main sequence, and we interpret our observational results in the light of the theoretical Rossby numbers. Results: The detected magnetic field of OU Andromedae (OU And) is a strong one. Its longitudinal component Bl reaches 40 G and presents an about sinusoidal variation with reversal of the polarity. The magnetic topology of OU And is dominated by large-scale elements and is mainly poloidal with an important dipole component, as well as a significant toroidal component. The detected magnetic field of 31 Comae (31 Com) is weaker, with a magnetic map showing a more complex field geometry, and poloidal and toroidal components of equal contributions. The evolutionary models show that the progenitors of OU And and 31 Com must have been rotating at velocities that correspond to 30 and 53%, respectively, of their critical rotation velocity on the zero age main sequence. Both OU And and 31 Com have very similar masses (2.7 and 2.85 M⊙, respectively), and they both lie in the Hertzsprung gap. Conclusions: OU And appears to be the probable descendant of a magnetic Ap star, and 31 Com the descendant of a relatively fast rotator on the main sequence. Because of the relatively fast rotation in the Hertzsprung gap and the onset of the development of a convective envelope, OU And also has a dynamo in operation. Based on observations obtained at the telescope Bernard Lyot (TBL) at Observatoire du Pic du Midi, CNRS/INSU and Université de Toulouse, France.

75 FR 54779 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-09

... appropriate. The NPL is designed primarily for informational purposes and to assist EPA management. Section... Packaging). OU3 GT Car Shop/Aspen 1235 South Jason Design and Street. Manufacturing. OU3 Denver right-of-way... radiation. [[Page 54785

Superfund record of decision amendment (EPA Region 10): USAF Eielson Air Force Base, Operable Units 3, 4, and 5, Fairbanks North Star Borough, AK, September 29, 1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This decision document presents the amended remedial action for Operable Units 3, 4, and 5 (OUs 3, 4, and 5) at Eielson Air Force Base (AFB). This decision is based on the Administrative Record for OU 3, 4, and 5, updated in July 1998, to include new information generated since the original Record of Decision was signed on 30 September 1995 (PB95-964618). This amendment applies to OU3 site DP44 (Battery Shop Leach Field Building), OU4 sites SS35 (Asphalt Mixing Area) and ST58 (Old Quartermaster Service Station), and OU5 sites LF03/FT09 (Current Inactive Base Landfill/Fire Training Area). Through new information, contaminantmore » levels than interpreted prior to signing the original ROD document. Proper enforcement of Institutional Controls (IC`s) at all sites will be effective in controlling and restricting access to contaminated media at the sites remediation goals are achieved.« less

Superfund record of decision amendment (EPA Region 5): Metamora Landfill Site, Metamora, MI, August 28, 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The United States Environmental Protection Agency (U.S. EPA) is changing a portion of the remedy selected in the operable unit one (OU1) Record of Decision (ROD) dated September 30, 1986, for the Metamora Landfill Site. Operable Unit 1 ROD (OU1 ROD) addresses the remediation of drummed waste and contaminated soils in Drum Area 1 and Drum Area 4. OU1 ROD selected off-site incineration of the drums and soils in Drum Area 1 and Drum Area 4. State lead remedial action work began in the spring of 1989 and continued until December 1990. During the summer of 1990, off-site incineration capacitymore » became extremely limited and drums awaiting disposal began to accumulate at the site. In addition, many more drums were discovered than originally estimated in the Remedial Design. In April of 1991 a settlement was reached that addressed the completion of all remedial activity remaining at the site, including the completion of OU1.« less

Superfund Record of Decision (EPA Region 8): Sand Creek Industrial Site, operable unit 5, Commerce City, CO, (amendment), September 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This decision document is an amendment to the Record of Decision (ROD) signed September 28, 1990 (PB94-921479) and presents the new selected remedial action for cleanup of contaminated shallow soils at OU5 at the Sand Creek Industrial Superfund Site. OU5 is located immediately north of 52nd and Dahlia Street in Commerce City, Colorado. Based on new technical data and cost information obtained subsequent to the September 1990 ROD, EPA has reconsidered its decision to employ soil washing and incineration of the generated residuals as a source control measure for OU5.

The Development of a Multidimensional Measure of Post-deployment Reintegration: Initial Psychometric Analyses & Descriptive Results (Final Report to Director General Health Services Quality of Life Research Grant)

DTIC Science & Technology

2003-12-01

différences constatées entre les groupes étudiés étaient associées à l’état matrimonial , à la présence de personnes à charge, au groupe professionnel et...population, sur les plans suivants : état matrimonial (deux groupes : soldats mariés contre soldats célibataires), enfants (deux groupes : soldats...ou de soutien) et nombre de déploiements antérieurs (trois groupes : un, deux ou trois déploiements ou plus). État matrimonial : Les expériences

Activite locomotrice de souris isolees, de deux lignees consanguines, dans un environnement semi-naturel ou en cages d'elevage.

PubMed

Le Pape, G; Lassalle, J M

1979-10-01

Des enregistrements continus d'activité locomotrice ont été effectués sur des souris mâles isolées des lignées Balb/c et C57bl/6, vivant en cages d'élevage ou en milieu semi- naturel. Les résultats montrent que les différences entre ces deux situations ne sont pas perçues de la même façon par les animaux des deux lign'ees: alors qu'en cages d'élevage les souris des deux lignées experiment la même quantité totale d'activaté, en milieu semi-naturel les souris Balb/c sont plus actives que les C57bl/6. En outre, l≐s différences observées entre les lignées pour la repartition de l'activité au cours du nycthèmere s'inversent lorsque l'on passe d'une situation à l'autre. L'étude de la variabilité fait aparaître une dispersion plus grande des performances dans la lignée C57bl/6 en cages d'élevage, alors qu'en milieu semi-naturel la dispersion est plus chez Bal/c. Copyright © 1979. Published by Elsevier B.V.

OU/OSU Study Committee, SB 1009.

ERIC Educational Resources Information Center

Oklahoma State Regents for Higher Education, Oklahoma City.

An Oklahoma State Legislature directive formed a committee to study University of Oklahoma (OU) and Oklahoma State University (OSU) services and programs and make recommendations for enhancement. The role of Oklahoma's two comprehensive research universities in the future of the state was the Committee's overriding consideration. Much discussion…

Large-Scale Pumping Test Recommendations for the 200-ZP-1 Operable Unit

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spane, Frank A.

2010-09-08

CH2M Hill Plateau Remediation Company (CHPRC) is currently assessing aquifer characterization needs to optimize pump-and-treat remedial strategies (e.g., extraction well pumping rates, pumping schedule/design) in the 200-ZP-1 operable unit (OU), and in particular for the immediate area of the 241 TX-TY Tank Farm. Specifically, CHPRC is focusing on hydrologic characterization opportunities that may be available for newly constructed and planned ZP-1 extraction wells. These new extraction wells will be used to further refine the 3-dimensional subsurface contaminant distribution within this area and will be used in concert with other existing pump-and-treat wells to remediate the existing carbon tetrachloride contaminant plume.more » Currently, 14 extraction wells are actively used in the Interim Record of Decision ZP-1 pump-and-treat system for the purpose of remediating the existing carbon tetrachloride contamination in groundwater within this general area. As many as 20 new extraction wells and 17 injection wells may be installed to support final pump-and-treat operations within the OU area. It should be noted that although the report specifically refers to the 200-ZP-1 OU, the large-scale test recommendations are also applicable to the adjacent 200-UP-1 OU area. This is because of the similar hydrogeologic conditions exhibited within these two adjoining OU locations.« less

Geology and hydrocarbon potential of the Oued Mya basin, Algeria

DOE Office of Scientific and Technical Information (OSTI.GOV)

Benamrane, O.; Messaoudi, M.; Messelles, H.

1993-09-01

The Oued Mya hydrocarbon system is located in the Sahara basin. It is one of the best producing basins in Algeria, along with the Ghadames and Illizi basins. The stratigraphic section consists of Paleozoic and Mesozoic, and is about 5000 m thick. This intracratonic basin is limited to the north by the Toughourt saddle, and to the west and east it is flanked by regional arches, Allal-Tilghemt and Amguid-Hassi Messaoud, which culminate in the super giant Hassi Messaoud and Hassi R'mel hydrocarbon accumulations, respectively, producing oil from the Cambrian sands and gas from the Trissic sands. The primary source rockmore » in this basin is lower Silurian shale, with an average thickness of 50 m and a total organic carbon of 6% (14% in some cases). Results of maturation modeling indicate that the lower Silurian source is in the oil window. The Ordovician shales are also source rocks, but in a second order. Clastic reservoirs are in the Trissic sequence, which is mainly fluvial deposits with complex alluvial channels, and the main target in the basin. Clastic reservoirs in the lower Devonian section have a good hydrocarbon potential east of the basin through a southwest-northwest orientation. The Late Trissic-Early Jurassic evaporites that overlie the Triassic clastic interval and extend over the entire Oued Mya basin, are considered to be a super-seal evaporite package, which consists predominantly of anhydrite and halite. For paleozoic targets, a large number of potential seals exist within the stratigraphic column. This super seal does not present oil dismigration possibilities. We can infer that a large amount of the oil generated by the Silurian source rock from the beginning of Cretaceous until now still is not discovered and significantly greater volumes could be trapped within structure closures and mixed or stratigraphic traps related to the fluvial Triassic sandstones, marine Devonian sands, and Cambrian-Ordovician reservoirs.« less

Letter from Prashant Gupta, Honeywell to Galo Jackson, USEPA. Subject: Draft Feasibility Study Report for OU1 (Estuary), LCP Chemicals Site

EPA Pesticide Factsheets

March 29, 2013 cover letter and report for Operable Unit 1 (OU1) to evaluate potential remedial measures at LCP Chemicals site in Brunswick, Georgia. Region ID : 04, DocID: 10940624 , DocDate: 2013-03-29

Letter from Prashant Gupta, Honeywell to Galo Jackson, USEPA. Subject: Draft Feasibility Study Report for OU 1 (Estuary)

EPA Pesticide Factsheets

October 16, 2013 letter and attachment with responses to June 20, 2013 comments by USEPA about the Operable Unit 1 (OU1) at the LCP Chemicals site in Brunswick, Georgia. Region ID: 04 DocID: 10944892, DocDate: 10-16-2013

Graduation Certification--Too Late to Graduate!

ERIC Educational Resources Information Center

Doman, Mark S.

2017-01-01

Oakland University (OU) in Rochester, Michigan, was experiencing growing pains. The good news was that OU had experienced 23 years of continuous enrollment growth, with student enrollment exceeding 20,000 in 2015 for the first time ever. The downside was that various administrative processes throughout the university were straining to keep up. One…

Sidi Ali Ou Azza (L4): A New Moroccan Fall

NASA Astrophysics Data System (ADS)

Chennaoui Aoudjehane, H.; Agee, C. B.; Aaranson, A.; Bouragaa, A.

2016-08-01

Sidi Ali Ou Azza is the latest meteorite fall in Morocco, it occurred on 28 July 2015 very close (about 40 km) to Tissint martian shergottite fall that occurred on 18 July 2011. It's one of the small group of 23 L4 ordinary chondrite falls.

Prescrire du cannabis fumé pour la douleur chronique non cancéreuse

PubMed Central

Kahan, Meldon; Srivastava, Anita; Spithoff, Sheryl; Bromley, Lisa

2014-01-01

Résumé Objectif Offrir des conseils préliminaires sur la prescription de cannabis fumé pour la douleur chronique avant la publication de lignes directrices officielles. Qualité des données Nous avons examiné les ouvrages scientifiques sur l’efficacité analgésique du cannabis fumé et les dommages causés par la consommation de cannabis à des fins médicales et récréatives. Nous avons élaboré des recommandations concernant les indications et les contre-indications du cannabis fumé, les précautions à prendre et son dosage et nous avons classé les recommandations en fonction du niveau des données probantes. La plupart des données probantes sont de niveau II (études observationnelles bien effectuées) et de niveau III (opinion d’experts). Message principal Le cannabis fumé pourrait être indiqué chez des patients souffrant de douleurs neuropathiques sévères qui n’ont pas répondu à des essais suffisants de cannabinoïdes pharmaceutiques et d’analgésiques standards (données probantes de niveau II). Le cannabis fumé est contre-indiqué chez les patients de 25 ans ou moins (données probantes de niveau II); ceux qui font actuellement ou ont fait par le passé une psychose ou encore ont de forts antécédents familiaux de psychose (données probantes de niveau II); ceux qui ont ou ont eu un problème de consommation de cannabis (données probantes de niveau III); ceux qui ont un problème actuel de toxicomanie ou d’alcoolisme (données probantes de niveau III); ceux qui ont une maladie cardiovasculaire ou respiratoire (données probantes de niveau III); ou celles qui sont enceintes ou planifient une grossesse (données probantes de niveau II). Il devrait être utilisé avec précaution par les patients qui fument du tabac (données probantes de niveau II), qui sont à risque accru de maladies cardiovasculaires (données probantes de niveau III), qui ont des troubles d’anxiété ou de l’humeur (données probantes de niveau II) ou qui prennent de fortes doses d’opioïdes ou de benzodiazépines (données probantes de niveau III). Il faut conseiller aux utilisateurs de cannabis d’attendre au moins 3 à 4 heures avant de conduire s’ils en ont fumé, au moins 6 heures s’ils en ont consommé par la bouche et au moins 8 heures s’ils ont ressenti un «high» subjectif (données probantes de niveau II). La dose maximale recommandée est de 1 inhalation 4 fois par jour (environ 400 mg par jour) de cannabis séché contenant 9 % de delta-9-tétrahydrocannabinol (données probantes de niveau III)). Les médecins devraient éviter de demander une consultation pour les patients auprès de cliniques «cannabinoïdes» (données probantes de niveau III). Conclusion Les lignes directrices futures devraient se fonder sur une révision systématique des ouvrages scientifiques sur la sécurité et l’efficacité du cannabis fumé. D’autres recherches sont nécessaires sur l’efficacité et la sécurité à long terme du cannabis fumé par rapport à d’autres cannabinoïdes pharmaceutiques, aux opioïdes et à d’autres analgésiques standards.

On the time-homogeneous Ornstein-Uhlenbeck process in the foreign exchange rates

NASA Astrophysics Data System (ADS)

da Fonseca, Regina C. B.; Matsushita, Raul Y.; de Castro, Márcio T.; Figueiredo, Annibal

2015-10-01

Since Gaussianity and stationarity assumptions cannot be fulfilled by financial data, the time-homogeneous Ornstein-Uhlenbeck (THOU) process was introduced as a candidate model to describe time series of financial returns [1]. It is an Ornstein-Uhlenbeck (OU) process in which these assumptions are replaced by linearity and time-homogeneity. We employ the OU and THOU processes to analyze daily foreign exchange rates against the US dollar. We confirm that the OU process does not fit the data, while in most cases the first four cumulants patterns from data can be described by the THOU process. However, there are some exceptions in which the data do not follow linearity or time-homogeneity assumptions.

Stability and Control of Tactical Missile Systems Held in Ankara (Turkey) on 9-12 May 1988

DTIC Science & Technology

1989-03-01

basic body for the systematic tests consisted of a cylindrical body with an ogive nose 3.0 calibers long for a total body length of 12.5 calibers A...Portance et stabilittd d’un Aiulege (ogies / iei 4 cylindre ) A N - 2.8. Compareison celcul "Euler" eec 1 d~~w~~hR~~t -- x~ine CALCUL -EULERV OPUP...toujours repr~sentatifs de Ia r~alit6. Compte tenu des pr~cisions recher- ch~es, lea effets du montage, d’un jet propulsif, du nombre de Reynolds, ou de

Luxation traumatique négligée de la hanche traitée par arthroplastie totale de la hanche: à propos de 2 cas

PubMed Central

Soufiane, Bensaad; Naserddine, Hammou; Atif, Mechchat; Abdelhamim, El Ibrahimi; Mohemmed, Shimi; Abdelmjide, Elmrini

2015-01-01

Les luxations négligées de la hanche sont des lésions exceptionnelles. Elle concerne généralement des traumatismes graves, où les lésions ostéo-articulaires ne sont pas minutieusement recherchées, ou relayer au second plan. L’évolution inéluctable se fait vers la nécrose de la tête fémorale et la coxarthrose. L'arthroplastie permet de raccourcir cette évolution et de réinsérer rapidement ces patients. PMID:26175804

Still Imagining the Future

ERIC Educational Resources Information Center

Baker, Chris

2009-01-01

The Open University, or the OU as it is more familiarly known, has reached middle age. The OU has a lot to celebrate. It has become UK's largest university, pioneered supported open learning, and provided access to a high-quality provision from which more than two million learners have benefitted. Internationally, it has many sister institutions…

Experiences with New Approach to Use of Information Technologies in Education

ERIC Educational Resources Information Center

Kostolányová, Katerina

2008-01-01

Paper describes approach of Department of Information and Communication technologies (KIK) on Pedagogical Faculty of University of Ostrava in Ostrava (PedF OU) to development of information knowledge and skills of students of OU with the aid of modern methods and education technologies with support of information technologies (IT). It surveys the…

Le sevrage de l’allaitement

PubMed Central

Grueger, Barbara

2013-01-01

RÉSUMÉ L’allaitement exclusif assure une alimentation optimale aux nourrissons jusqu’à l’âge de six mois. Par la suite, les nourrissons ont besoin d’aliments complémentaires pour répondre à leurs besoins nutritionnels. C’est alors que le sevrage commence. Le sevrage désigne le processus graduel d’introduction d’aliments complémentaires au régime du nourrisson, tout en poursuivant l’allaitement. Il n’y a pas de moment universellement accepté ou scientifiquement démontré pour mettre un terme à l’allaitement. Le moment et le processus de sevrage doivent être adaptés par la mère et l’enfant. Le sevrage peut être soudain ou graduel, prendre plusieurs semaines ou plusieurs mois, être dirigé par l’enfant ou par la mère. Les médecins doivent orienter et soutenir les mères tout au long du processus de sevrage. Le présent document remplace le document de principes sur le sevrage qu’a publié la Société canadienne de pédiatrie en 2004.

Selected natural attenuation monitoring data, Operable Unit 1, Naval Undersea Warfare Center, Division Keyport, Washington, June 2002

USGS Publications Warehouse

Dinicola, Richard S.

2004-01-01

Previous investigations indicated that natural attenuation and biodegradation of chlorinated volatile organic compounds (CVOCs) are substantial in shallow ground water beneath the 9-acre former landfill at Operable Unit 1 (OU 1), Naval Undersea Warfare Center (NUWC), Division Keyport, Washington. The U.S. Geological Survey (USGS) has continued to monitor ground-water geochemistry to assure that conditions remain favorable for contaminant biodegradation. This report presents the geochemical and selected CVOC data for ground water at OU 1, collected by the USGS during June 10-14, 2002, in support of long-term monitoring for natural attenuation. Overall, the geochemical data for June 2002 indicate that redox conditions in the upper-aquifer water remain favorable for reductive dechlorination of chlorinated VOCs because strongly reducing conditions persisted beneath much of the former landfill. Redox conditions in the intermediate aquifer downgradient of the landfill also remained favorable for reductive dechlorination, although the 2002 dissolved hydrogen (H2) concentration from well MW1-28 is questionable. Changes in redox conditions were observed at certain wells during 2002, but a longer monitoring period and more thorough interpretation are needed to ascertain if phytoremediation activities are affecting redox conditions and if biodegradation processes are changing over time. The Navy intends to complete a more thorough interpretation in preparation for the 5-year review of OU 1 scheduled for 2004. There were a few substantial differences between the 2002 concentrations and previously observed concentrations of volatile organic compounds. Total CVOC concentrations in 2002 samples decreased substantially in all piezometers sampled in the northern plantation, and the largest percentages of decrease were for the compounds trichloroethene (TCE) and cis-1,2-dichloroethene (cis-DCE). Changes in total CVOC concentrations in the southern plantation were less consistent. Historically high concentrations were observed in samples from three piezometers, with particularly substantial increases in TCE and cis-DCE concentrations, and historically low concentrations were observed in two piezometers, with particularly substantial decreases in TCE and cis-DCE concentrations. Similarly to the redox chemistry, a longer monitoring period and more thorough interpretation are needed to ascertain if phytoremediation activities are affecting CVOC concentrations and if biodegradation processes are changing over time. No changes in monitoring plans are proposed for June 2003, although the practice of deploying a data sonde downhole while purging the wells will be discontinued. Downhole monitoring added uncertainty to selected measured dissolved H2 concentrations because of the possibility that the sonde and cable created a bridge that resulted in non-equilibrium dissolved H2 concentrations at the wells.

Using Interactive Videodiscs in Open University Courses. I.E.T. Papers on Broadcasting No. 218.

ERIC Educational Resources Information Center

Fuller, Robert G., Ed.

This nine-paper collection from a June 1983 Open University (OU) campus workshop in Milton Keynes, England, describes an interactive video project developed for an OU undergraduate course, T252, Introduction to Engineering Materials, and discusses varied aspects of interactive videodisc program development. The following papers are included:…

Is Developing Employability Skills Relevant to Adult Language Students?

ERIC Educational Resources Information Center

Beaven, Tita

2016-01-01

Open University (OU) students are typically mature students who combine studying part-time with work or caring responsibilities; the average age of OU language students has been dropping, and about 30% of our new students are now under 25. The traditional view of adult learners who study languages is that they often study for pleasure or personal…

FIELD SCALE EVALUATION OF TREATMENT OF TCE IN A BIOWALL AT THE OU-1 SITE

EPA Science Inventory

A passive reactive barrier (Biowall) was installed at the OU-1 site at Altus Air Force Base, Oklahoma to treat TCE contamination in ground water from a landfill. Depth to ground water varies from 1.8 to 2.4 meters below land surface. To intercept and treat the plume of contamin...

75 FR 44920 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-30

... is designed primarily for informational purposes and to assist EPA management. Section 300.425(e)(3... building or asphalt pavement. Primary operations at the SMS Instruments facility consisted of overhauling... settlement with EPA in 1988 and the EPA took over all work associated with OU-1 and OU-2 Remedial Design and...

Teaching Biology at a Distance: Pleasures, Pitfalls, and Possibilities

ERIC Educational Resources Information Center

MacQueen, Hilary; Thomas, Jeff

2009-01-01

The Open University (OU) has a long and distinguished history of teaching biology at a distance by a supported open learning model. This article examines some of the challenges in delivering biology via distance teaching, explores some of the lessons learned, and discusses the opportunities and hazards of new teaching technologies that the OU has…

Superfund record of decision (EPA Region 3): Langley AFB/NASA Langley Center, Tabbs Creek Operable Unit, Hampton, VA, September 30, 1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-10-01

This Record of Decision (ROD) presents remedial action for the Tabbs Creek Operable Unit (OU) at the NASA Langley Research Center (LaRC) in Hampton, Virginia (the Site). This action addresses the principle threat at the OU by dredging and disposing contaminated sediment.

UNDERSTANDING THE INTERNATIONAL CONSENSUS FOR ACUTE PANCREATITIS: CLASSIFICATION OF ATLANTA 2012.

PubMed

Souza, Gleim Dias de; Souza, Luciana Rodrigues Queiroz; Cuenca, Ronaldo Máfia; Jerônimo, Bárbara Stephane de Medeiros; Souza, Guilherme Medeiros de; Vilela, Vinícius Martins

2016-01-01

Contrast computed tomography and magnetic resonance imaging are widely used due to its image quality and ability to study pancreatic and peripancreatic morphology. The understanding of the various subtypes of the disease and identification of possible complications requires a familiarity with the terminology, which allows effective communication between the different members of the multidisciplinary team. Demonstrate the terminology and parameters to identify the different classifications and findings of the disease based on the international consensus for acute pancreatitis ( Atlanta Classification 2012). Search and analysis of articles in the "CAPES Portal de Periódicos with headings "acute pancreatitis" and "Atlanta Review". Were selected 23 articles containing radiological descriptions, management or statistical data related to pathology. Additional statistical data were obtained from Datasus and Population Census 2010. The radiological diagnostic criterion adopted was the Radiology American College system. The "acute pancreatitis - 2012 Rating: Review Atlanta classification and definitions for international consensus" tries to eliminate inconsistency and divergence from the determination of uniformity to the radiological findings, especially the terminology related to fluid collections. More broadly as "pancreatic abscess" and "phlegmon" went into disuse and the evolution of the collection of patient fluids can be described as "acute peripancreatic collections", "acute necrotic collections", "pseudocyst" and "necrosis pancreatic walled or isolated". Computed tomography and magnetic resonance represent the best techniques with sequential images available for diagnosis. Standardization of the terminology is critical and should improve the management of patients with multiple professionals care, risk stratification and adequate treatment. A tomografia computadorizada contrastada e a ressonância magnética são exames amplamente utilizados no estudo da morfologia pancreática e peripancreática. O entendimento dos diversos subtipos da doença e identificação de suas possíveis complicações requer familiaridade com a terminologia padrão, a qual permite comunicação efetiva entre os diversos membros da equipe multidisciplinar. Demonstrar terminologia e os parâmetros para identificação das diferentes classificações da doença a partir do consenso internacional para as pancreatites agudas (Classificação de Atlanta 2012. Busca e análise de artigos no "Portal de Periódicos da CAPES" com descritores "pancreatite aguda" e "Revisão de Atlanta". : Foram selecionados 23 artigos que continham descrições radiológicas, manejo ou dados estatísticos relacionados à doença. Dados estatísticos adicionais foram obtidos no sistema Datasus e Censo Demográfico 2010. O critério de diagnóstico radiológico adotado foi o do Colégio Americano de Radiologia. A "Classificação da pancreatite aguda - 2012: revisão da classificação de Atlanta e definições por consenso internacional" tenta eliminar a inconsistência e divergências a partir da determinação de uniformidade para os achados radiológicos, em especial à terminologia relacionada às coleções de fluidos. Termos mais abrangentes como "abscesso pancreático" e "flegmão" entraram em desuso e a evolução da coleção de fluidos pode ser descrita como: "coleções peripancreáticas agudas", "coleções necróticas agudas", "pseudocisto" e "necrose pancreática murada ou isolada". A tomografia computadorizada e a ressonância magnética representam as melhores técnicas com cortes sequenciais disponíveis para diagnóstico. A adequação da terminologia é ponto crítico e deve permitir o manejo do paciente por múltiplos profissionais, estratificação de risco e adequação de tratamento.

Post-Closure Land Jurisdiction Transfer to the US Fish and Wildlife Service at Rocky Flats: Surviving the Safari Through Old Records and Other Lessons Learned

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schiesswohl, S.; Hanson, M.

The U.S. Department of Energy's (DOE's) Rocky Flats Site (Rocky Flats), located near Denver, Colorado, was listed on the Comprehensive Environmental Response, Compensation, and Liability Act National Priorities List (NPL) in 1989. Subsequent cleanup and closure activities were completed in October 2005 and the final remedy was selected in September 2006. The remedy is 'no further action' for the generally un-impacted Peripheral Operable Unit (OU), formerly known as the Buffer Zone, and institutional and physical controls with continued monitoring for the Central OU, formerly the industrialized area. The Peripheral OU has been deleted from the NPL and jurisdiction over themore » majority of land in that OU (3,953 acres) was transferred to the U.S. Fish and Wildlife Service (USFWS) on July 12, 2007, to establish the Rocky Flats National Wildlife Refuge. The remaining approximately 929 acres in the Peripheral OU were retained by DOE's Office of Legacy Management where outstanding mineral leases and mining operations exist. As mineral rights are purchased or mining operations and mineral leases are completed and fully reclaimed, jurisdiction of portions of the 929 acres will also be transferred to USFWS for inclusion into the refuge. During the almost 2 years since cleanup and closure work was completed at Rocky Flats, DOE and USFWS have worked the specific legal parameters, timing, and constraints of the 3,953-acre transfer. Many lessons have been learned, based on these early experiences. (authors)« less

How OpenLearn Supports a Business Model for OER

ERIC Educational Resources Information Center

Law, Patrina; Perryman, Leigh-Anne

2017-01-01

In 2013, the Open University (OU) in the UK launched a large-scale survey of users of its OpenLearn platform for open educational resources. The survey results revealed that OpenLearn is functioning as a showcase and a taster for the OU, thereby offering informal learners a bridge to formal education. In 2014 and 2015, the OpenLearn survey was…

Cardiomyopathie du péripartum: à propos d’une observation et revue de la littérature

PubMed Central

Bouzerda, Abdelmajid

2016-01-01

La cardiomyopathie du péripartum ou cardiomyopathie gravidique primitive, est une entité rare et méconnue définie comme une insuffisance cardiaque systolique survenant le dernier mois de la grossesse ou les cinq premiers mois du postpartum en l'absence d'étiologie connue ou de cardiopathie préexistante. Nous rapportons l'observation d'une jeune patiente de 31 ans sans antécédents pathologiques particuliers admise pour une poussée d'insuffisance cardiaque gauche 1mois après son accouchement. Le contexte de péripartum nous a fait penser au diagnostic et a motivé la réalisation d'une Echocardiographie qui a confirmé cette entité. PMID:28154713

A Numerical Investigation of the Non-Linear Mechanics of Wave Disturbances in Plane Poiseuille Flows

DTIC Science & Technology

1971-09-02

i OCXXLL UJ rn - •• • O •>a£ •> O »QC • S —nt-Q£ 00_IUJ< O0_IUJ< XLUI—LU QU< • OU< • *.< •>_! »•< »-J Z •Q.NOZ ROCOCO ...OU< * OU< *U- ^"O •X •» »Oi-i »<t *—J *< *—I »—<CM z ••a.cMoz Rococo -l-ocoto—• •»** o<<<x«-i • ora-<i- oru.<ti-FHO—z JUJO’-’Z...roro CO ro rococo OOOOOOOOOOOOOO oooooooooooooo oooooooooooooo oooooooooooooo ooooooooooooooooooooooooo co C* o -* c\\j ro -4- i n >o l*» oo cr

Institutional Change for Improving Accessibility in the Design and Delivery of Distance Learning--The Role of Faculty Accessibility Specialists at the Open University

ERIC Educational Resources Information Center

Slater, Rachel; Pearson, Victoria K.; Warren, James P.; Forbes, Tina

2015-01-01

The Open University (OU) has an established infrastructure for supporting disabled students. Historically, the thrust of this has focused on providing accessible adjustments post-production. In 2012, the OU implemented securing greater accessibility (SeGA) to raise awareness and bring about an institutional change to curriculum design so that the…

VHF Broadband Digital Interferometer for Real-time Operation

NASA Astrophysics Data System (ADS)

Kawasaki, Z. I.; Morimoto, T.; Akita, M.; Nakamura, Y.; Ushio, T.

2008-12-01

Lightning Research Group of Osaka University (LRG-OU) has been developing a VHF lightning mapper, Broadband Digital Interferometer (BDITF), to investigate lightning initiation and progression since 1995. When LRG-OU started the project, a multichannel digital storage oscilloscope was deployed to record VHF waveforms emitted by lightning discharges. VHF broadband antenna and necessary electronics like an amplifier were redesigned. Original VHF BDITF was operated in a rocket-triggered lightning experiment during winter thunderstorm season in Hokuriku, Japan. The first observation by BDITF was a rocket-triggered lightning, which lowered the positive charge to the ground. That meant ascending negative breakdown propagation was recorded, and LRG-OU obtained the lightning channel image by upward triggered lightning. Since LRGOU could validate the function and capability of BDITF through several field campaigns, a project to design and manufacture a special analog to digital converter for BDITF was initiated in 1998. Moreover software for a real-time data processing was developed. The first system of new BDITF was operated during a filed campaign in 2003, and lightning channels in two dimensions (2D), which meant azimuth and elevation format, were able to be reconstructed in a several seconds after occurrence of lightning flash. The BDITF system was considered to be an operational system recently. For three dimensional (3D) imaging, two sites operation of BDITF and post data processing of the triangulation are required. LRG-OU learned the bi- directional leader progression, possible charge distribution related to the leader initiation, and the speed of the leader propagation by the 3D imaging. The achievement of BDITF technique by LRG-OU gives us the chance of deployment and operation of the system around the rocket launching site of JAXA on the Tanegashima island. This operation is expected to contribute the go/no-go judgment of rocket launching by JAXA because of the now casting the location of lightning discharges. LRG-OU also joins in the several satellite projects. BDITF system which can be deployed on the satellite and/or space station is manufactured. The first VHF system is expected to be in the space in early 2009.

Hong-Ou-Mandel Interference between Two Deterministic Collective Excitations in an Atomic Ensemble

NASA Astrophysics Data System (ADS)

Li, Jun; Zhou, Ming-Ti; Jing, Bo; Wang, Xu-Jie; Yang, Sheng-Jun; Jiang, Xiao; Mølmer, Klaus; Bao, Xiao-Hui; Pan, Jian-Wei

2016-10-01

We demonstrate deterministic generation of two distinct collective excitations in one atomic ensemble, and we realize the Hong-Ou-Mandel interference between them. Using Rydberg blockade we create single collective excitations in two different Zeeman levels, and we use stimulated Raman transitions to perform a beam-splitter operation between the excited atomic modes. By converting the atomic excitations into photons, the two-excitation interference is measured by photon coincidence detection with a visibility of 0.89(6). The Hong-Ou-Mandel interference witnesses an entangled NOON state of the collective atomic excitations, and we demonstrate its two times enhanced sensitivity to a magnetic field compared with a single excitation. Our work implements a minimal instance of boson sampling and paves the way for further multimode and multiexcitation studies with collective excitations of atomic ensembles.

Multiparametric magnetic resonance imaging findings of prostatic pure leiomyomas.

PubMed

Mussi, Thais Caldara; Costa, Yves Bohrer; Obara, Marcos Takeo; Queiroz, Marcos Roberto Gomes de; Garcia, Rodrigo Gobbo; Longo, José Antonio Domingos Cianciarulo; Lemos, Gustavo Caserta; Baroni, Ronaldo Hueb

2016-01-01

To describe the imaging findings of prostatic tumors nonadenocarcinoma on multiparametric magnetic resonance imaging. A total of 200 patients underwented multiparametric magnetic resonance imaging of the prostate for screening for prostate cancer, from August 2013 to September 2014, followed by biopsy with ultrasound/magnetic resonance imaging fusion. We found three pathologic proved cases of prostatic pure leiomyomas (0.02%) in our series and described the multiparametric magnetic resonance imaging features of these prostatic leiomyomas. The imaging findings had similar features to lesions with moderate or high suspicion for significant cancer (Likert 4 or 5) when localized both in the transitional zone or in the peripheral zone of the gland. Pure prostatic leiomyomas had imaging findings on multiparametric magnetic resonance imaging that mimicked usual adenocarcinomas on this test. Radiologists, urologists and pathologists must be aware of this entity and its imaging features. Descrever os achados de imagem de tumores prostáticos não adenocarcinoma na ressonância magnética multiparamétrica. Realizaram ressonância magnética multiparamétrica da próstata para detecção de câncer de próstata 200 pacientes de agosto de 2013 a setembro de 2014, seguida por biópsia com fusão de imagens de ultrassonografia/ressonância magnética. Encontramos três casos confirmados histologicamente de leiomiomas prostáticos puros (0,02%) em nossa casuística e descrevemos os achados da ressonância magnética multiparamétrica destes casos de leiomiomas. Os achados de imagem foram semelhantes aos de lesões com moderada ou alta suspeição para neoplasia clinicamente significante (Likert 4 ou 5) quando localizados na zona de transição ou zona periférica da próstata. Leiomiomas puros da próstata tiveram achados de imagem na ressonância magnética multiparamétrica que mimetizaram adenocarcinomas. Radiologistas, urologistas e patologistas devem estar cientes destas entidades e seus achados de imagem.

Lait humain provenant d’une banque de dons ou acheté en ligne?

PubMed Central

St-Onge, Maude; Chaudhry, Shahnaz; Koren, Gideon

2015-01-01

Résumé Question Une de mes patientes m’a demandé si elle pourrait se procurer du lait humain par Internet pour allaiter son nourrisson s’il le fallait. L’usage de lait humain provenant d’une banque de dons est-il plus sécuritaire que son achat en ligne? Réponse L’Organisation mondiale de la Santé et l’American Academy of Pediatrics recommandent d’utiliser des dons de lait humain comme choix à privilégier lorsque le lait maternel n’est pas disponible. Cependant, la Société canadienne de pédiatrie n’approuve pas le partage de lait humain non traité. Le lait humain entreposé dans les banques de lait diffère de celui qu’on peut se procurer par Internet en raison du processus rigoureux de sélection des donneuses, des fréquentes inspections de la qualité, des procédés de transport règlementés et du processus de pasteurisation conforme aux directives établies par l’Agence canadienne d’inspection des aliments. La plupart des échantillons achetés en ligne contiennent des bactéries à gram négatif ou comptent au total plus de 104 unités formant colonies de bactéries aérobiques par millilitre; ils renferment aussi en moyenne au décompte total plus de bactéries aérobiques, de bactéries à gram négatif, de coliformes et de Staphylococcus spp que les échantillons des banques de lait. La croissance de la plupart des espèces de bactéries est associée au nombre de jours en transit, ce qui porte à croire que les conditions de collecte, d’entreposage et de transport sont médiocres pour le lait acheté en ligne.

Le syndrome du canal d’Alcock ou névralgie pudendale : un diagnostic à ne pas méconnaître

PubMed Central

Ziouziou, Imad; Bennani, Hassan; Zizi, Mohamed; Karmouni, Tarik; Khader, Khalid El; Koutani, Abdellatif; Andaloussi, Ahmed Iben Attya

2013-01-01

Résumé Le syndrome du canal d’Alcock – ou névralgie pudendale – est lié à la compression chronique du nerf pudendal dans la fossette ischiorectale ou au niveau du ligament sacroépineux. Le diagnostic du syndrome d’Alcock est surtout clinique. Les examens complémentaires sont dominés par les explorations électrophysiologiques et le test de bloc anesthésique. Le diagnostic repose sur des critères bien précis, soit les critères de Nantes. La prise en charge doit être globale, comprenant un traitement médicamenteux, des infiltrations, des techniques de neuromodulation, et dans les cas graves ou résistants, un traitement chirurgical qui consiste à libérer le nerf pudendal. Les névralgies pudendales peuvent être rencontrées après traitement d’une incontinence urinaire d’effort par bande-lettes sous-urétrales (TVT). Ce syndrome motive des consultations en urologie, car la douleur intéresse le territoire du périnée et des organes génitaux. Des signes urinaires peuvent aussi accompagner cette douleur. Il est donc judicieux de connaître cette pathologie. PMID:23914265

Prediction of Aerodynamic Loads on Rotorcraft.

DTIC Science & Technology

1982-09-01

CALCULATION ON HORIZONTAL AXIS WIND TURBINE IN NON UNIFORM FLOW by E.Lupo 6 PREDICTION ET VERIFICATION EXPERIMENTALE DU CHAMP DES VITESSES D’UN ROTOR...calculs, do plus en plus sophistiqugs, tridimensionnols quasi -stationnairos ou instationnaires non portants ou portents, mime our pale isolfe do rotor...exemple d’dquations de Ia mdcanique des pales. Ces 6quationa sont quasi lin~aires en fonc- tion des portances mgme non lindaires. L’a6rodynamique examinde

A Study of Co-Relation between the Length of English Low Vowels and Diphthongs by Korean Exchange Students

ERIC Educational Resources Information Center

Park, Heesuk

2010-01-01

This paper aims at comparing the five English diphthongs, /ei/, /ou/, /au/, /ai/, /[inverted c]i/, in the aspect of length, to find out a common feature in /au/, ai/, /[inverted c]i/ and /ei/, and /ou/ and to see if there is any evidence between English low vowels and diphthongs. This study is a following research of Park (2009), and I analyzed…

[Not Available].

PubMed

Haza, Marion

2012-08-01

Dans cet article, nous abordons la question de l'accès à la pornographie sur Internet par les adolescents. Nous déclinons plusieurs facettes de ces rencontres: la rencontre «fortuite», quand les adolescents sont confrontés à des images intempestives, des publicités ou spams avec des contenus pornographiques; la rencontre «spectatrice», quand les adolescents cherchent activement des vidéos ou photos mettant en scène la sexualité; et enfin la rencontre «actrice», quand les adolescents se mettent en scène eux-mêmes, seuls ou à plusieurs, de façon pornographique sur le Net. A partir d'exemple, nous réfléchissons aux enjeux de ces rencontres virtuelles précoces de la sexualité adulte par rapport au développement adolescent et à la représentation de leur propre sexualité en construction.

Adolescence et pornographie sur la toile

PubMed Central

Haza, Marion

2012-01-01

Dans cet article, nous abordons la question de l’accès à la pornographie sur Internet par les adolescents. Nous déclinons plusieurs facettes de ces rencontres: la rencontre «fortuite», quand les adolescents sont confrontés à des images intempestives, des publicités ou spams avec des contenus pornographiques; la rencontre «spectatrice», quand les adolescents cherchent activement des vidéos ou photos mettant en scène la sexualité; et enfin la rencontre «actrice», quand les adolescents se mettent en scène eux-mêmes, seuls ou à plusieurs, de façon pornographique sur le Net. A partir d’exemple, nous réfléchissons aux enjeux de ces rencontres virtuelles précoces de la sexualité adulte par rapport au développement adolescent et à la représentation de leur propre sexualité en construction. PMID:22876261

Divergent effects of compounds on the hydrolysis and transpeptidation reactions of γ-glutamyl transpeptidase.

PubMed

Wickham, Stephanie; Regan, Nicholas; West, Matthew B; Kumar, Vidya Prasanna; Thai, Justin; Li, Pui Kai; Cook, Paul F; Hanigan, Marie H

2012-08-01

A novel class of inhibitors of the enzyme γ-glutamyl transpeptidase (GGT) were evaluated. The analog OU749 was shown previously to be an uncompetitive inhibitor of the GGT transpeptidation reaction. The data in this study show that it is an equally potent uncompetitive inhibitor of the hydrolysis reaction, the primary reaction catalyzed by GGT in vivo. A series of structural analogs of OU749 were evaluated. For many of the analogs, the potency of the inhibition differed between the hydrolysis and transpeptidation reactions, providing insight into the malleability of the active site of the enzyme. Analogs with electron withdrawing groups on the benzosulfonamide ring, accelerated the hydrolysis reaction, but inhibited the transpeptidation reaction by competing with a dipeptide acceptor. Several of the OU749 analogs inhibited the transpeptidation reaction by slow onset kinetics, similar to acivicin. Further development of inhibitors of the GGT hydrolysis reaction is necessary to provide new therapeutic compounds.

Generalized quantum interference of correlated photon pairs.

PubMed

Kim, Heonoh; Lee, Sang Min; Moon, Han Seb

2015-05-07

Superposition and indistinguishablility between probability amplitudes have played an essential role in observing quantum interference effects of correlated photons. The Hong-Ou-Mandel interference and interferences of the path-entangled photon number state are of special interest in the field of quantum information technologies. However, a fully generalized two-photon quantum interferometric scheme accounting for the Hong-Ou-Mandel scheme and path-entangled photon number states has not yet been proposed. Here we report the experimental demonstrations of the generalized two-photon interferometry with both the interferometric properties of the Hong-Ou-Mandel effect and the fully unfolded version of the path-entangled photon number state using photon-pair sources, which are independently generated by spontaneous parametric down-conversion. Our experimental scheme explains two-photon interference fringes revealing single- and two-photon coherence properties in a single interferometer setup. Using the proposed interferometric measurement, it is possible to directly estimate the joint spectral intensity of a photon pair source.

Simulation of solute transport of tetrachloroethylene in ground water of the glacial-drift aquifer at the Savage Municipal Well Superfund Site, Milford, New Hampshire, 1960-2000

USGS Publications Warehouse

Harte, Philip T.

2004-01-01

The Savage Municipal Well Superfund site, named after the former municipal water-supply well for the town of Milford, is underlain by a 0.5-square mile plume of volatile organic compounds (VOCs), primarily tetrachloroethylene (PCE). The plume occurs mostly within a highly transmissive sand-and-gravel unit, but also extends to an underlying till and bedrock unit. The plume logistically is divided into two areas termed Operable Unit No. 1 (OU1), which contains the primary source area, and Operable Unit No. 2 (OU2), which is the extended plume area. PCE concentrations in excess of 100,000 parts per billion (ppb) had been detected in the OU1 area in 1995, indicating a likely Dense Non-Aqueous Phase Liquid (DNAPL) source. In the fall of 1998, the New Hampshire Department of Environmental Services (NHDES) and the U.S. Environmental Protection Agency (USEPA) installed a remedial system in OU1. The OU1 remedial system includes a low-permeability barrier that encircles the highest detected concentrations of PCE, and a series of injection and extraction wells. The barrier primarily sits atop bedrock and penetrates the full thickness of the sand and gravel; and in some places, the full thickness of the underlying basal till. The sand and gravel unit and the till comprise the aquifer termed the Milford-Souhegan glacial-drift aquifer (MSGD). Two-dimensional and three-dimensional finite-difference solute-transport models of the unconsolidated sediments (MSGD aquifer) were constructed to help evaluate solute-transport processes, assess the effectiveness of remedial activities in OU1, and to help design remedial strategies in OU2. The solute-transport models simulate PCE concentrations, and model results were compared to observed concentrations of PCE. Simulations were grouped into the following three time periods: an historical calibration of the distribution of PCE from the initial input (circa 1960) of PCE into the subsurface to the 1990s, a pre-remedial calibration from 1995 to 1998, and a remedial (post-barrier wall) calibration from 1998 to 1999. Model results also were checked against observed PCE concentrations from May and June 2000 as a post-audit of model performance. Results of the simulations of the two-dimensional model for the historical calibration indicate that the model-computed length of the plume is affected by the retardation factor (retardation). Values of retardation greater than 3 caused the longitudinal length of the computed plume to be too short compared to the observed plume. A retardation of 2-2.5 produced a reasonable comparison between computed and observed PCE concentrations. Testing of different starting times and rates of mass input of PCE indicated that the plume reaches a quasi steady-state distribution in about 20 years regardless of the rate of mass input or values of the solute-transport parameters (retardation, dispersion, and irreversible reaction) assigned the model. Results of the simulations of the three-dimensional model for the pre-remedial (1995-98) calibration of PCE for the OU2 area identified some spatial biases in computed concentrations that generally were unaffected by changes in retardation. The computed PCE concentrations exceeded observed concentrations along the northern part of the plume in OU2, where PCE increases were observed in a bedrock well. These results indicate that some PCE in this area may be entering the bedrock, which is not simulated in the model. Conversely, computed PCE concentrations were less than observed concentrations along the southern part of the plume in OU2. Because testing of high (above 4) values of retardation did little to reduce residuals, it is concluded that the low computed PCE concentrations along the southern flank are likely the result of an underestimation of the initial PCE mass in this area or an unaccounted source of PCE. Results of the simulations of the three-dimensional model for the remedial calibration period (1998-99) and po

Remedial investigation work plan for Bear Creek Valley Operable Unit 1 (S-3 Ponds, Boneyard/Burnyard, Oil Landfarm, Sanitary Landfill 1, and the Burial Grounds, including Oil Retention Ponds 1 and 2) at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee. Volume 1, Main text

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-09-01

The intent and scope of the work plan are to assemble all data necessary to facilitate selection of remediation alternatives for the sites in Bear Creek Valley Operable Unit 1 (BCV OU 1) such that the risk to human health and the environment is reduced to acceptable levels based on agreements with regulators. The ultimate goal is to develop a final Record Of Decision (ROD) for all of the OUs in BCV, including the integrator OU. However, the initial aim of the source OUs is to develop a ROD for interim measures. For source OUs such as BCV OU 1,more » data acquisition will not be carried out in a single event, but will be carried out in three stages that accommodate the schedule for developing a ROD for interim measures and the final site-wide ROD. The three stages are as follows: Stage 1, Assemble sufficient data to support decisions such as the need for removal actions, whether to continue with the remedial investigation (RI) process, or whether no further action is required. If the decision is made to continue the RI/FS process, then: Stage 2, Assemble sufficient data to allow for a ROD for interim measures that reduce risks to the human health and the environment. Stage 3, Provide input from the source OU that allows a final ROD to be issued for all OUs in the BCV hydrologic regime. One goal of the RI work plan will be to ensure that sampling operations required for the initial stage are not repeated at later stages. The overall goals of this RI are to define the nature and extent of contamination so that the impact of leachate, surface water runoff, and sediment from the OU I sites on the integrator OU can be evaluated, the risk to human health and the environment can be defined, and the general physical characteristics of the subsurface can be determined such that remedial alternatives can be screened.« less

Monticello Mill Tailings Site, Operable Unit lll, Annual Groundwater Report, May 2015 Through April 2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nguyen, Jason; Smith, Fred

This report provides the annual analysis of water quality restoration progress, cumulative through April 2016, for Operable Unit (OU) III, surface water and groundwater, of the U.S. Department of Energy (DOE) Office of Legacy Management (LM) Monticello Mill Tailings Site (MMTS). The MMTS is a Comprehensive Environmental Response, Compensation, and Liability Act National Priorities List site located in and near the city of Monticello, San Juan County, Utah. MMTS comprises the 110-acre site of a former uranium- and vanadium-ore-processing mill (mill site) and 1700 acres of surrounding private and municipal property. Milling operations generated 2.5 million cubic yards of wastemore » (tailings) from 1942 to 1960. The tailings were impounded at four locations on the mill site. Inorganic constituents in the tailings drained from the impoundments to contaminate local surface water (Montezuma Creek) and groundwater in the underlying alluvial aquifer. Mill tailings dispersed by wind and water also contaminated properties surrounding and downstream of the mill site. Remedial actions to remove and isolate radiologically contaminated soil, sediment, and debris from the former mill site, Operable Unit I (OU I), and surrounding properties (OU II) were completed in 1999 with the encapsulation of the wastes in an engineered repository located on DOE property 1 mile south of the former mill site. This effectively removed the primary source of groundwater contamination; however, contamination of groundwater and surface water remains within OU III at levels that exceed water quality protection standards. Uranium is the primary contaminant of concern (COC). LM implemented monitored natural attenuation with institutional controls as the OU III remedy in 2004. Because groundwater restoration proceeded more slowly than expected and did not meet performance criteria established in the OU III Record of Decision (June 2004), LM implemented a contingency action in 2009 by an Explanation of Significant Difference to include a pump-and­ treat system using a single extraction well and treatment by zero-valent iron (ex situ treatment system). The contingency action was optimized in 2015 with the installation of8 extraction wells and 16 monitoring wells in a focused area of the aquifer, the area of attainment (AOA). Contaminated water is treated by solar evaporation at an existing facility at the LM repository.« less

Caracterisation des proprietes acoustiques des materiaux poreux a cellules ouvertes et a matrice rigide ou souple

NASA Astrophysics Data System (ADS)

Salissou, Yacoubou

L'objectif global vise par les travaux de cette these est d'ameliorer la caracterisation des proprietes macroscopiques des materiaux poreux a structure rigide ou souple par des approches inverses et indirectes basees sur des mesures acoustiques faites en tube d'impedance. La precision des approches inverses et indirectes utilisees aujourd'hui est principalement limitee par la qualite des mesures acoustiques obtenues en tube d'impedance. En consequence, cette these se penche sur quatre problemes qui aideront a l'atteinte de l'objectif global precite. Le premier probleme porte sur une caracterisation precise de la porosite ouverte des materiaux poreux. Cette propriete en est une de passage permettant de lier la mesure des proprietes dynamiques acoustiques d'un materiau poreux aux proprietes effectives de sa phase fluide decrite par les modeles semi-phenomenologiques. Le deuxieme probleme traite de l'hypothese de symetrie des materiaux poreux selon leur epaisseur ou un index et un critere sont proposes pour quantifier l'asymetrie d'un materiau. Cette hypothese est souvent source d'imprecision des methodes de caracterisation inverses et indirectes en tube d'impedance. Le critere d'asymetrie propose permet ainsi de s'assurer de l'applicabilite et de la precision de ces methodes pour un materiau donne. Le troisieme probleme vise a mieux comprendre le probleme de transmission sonore en tube d'impedance en presentant pour la premiere fois un developpement exact du probleme par decomposition d'ondes. Ce developpement permet d'etablir clairement les limites des nombreuses methodes existantes basees sur des tubes de transmission a 2, 3 ou 4 microphones. La meilleure comprehension de ce probleme de transmission est importante puisque c'est par ce type de mesures que des methodes permettent d'extraire successivement la matrice de transfert d'un materiau poreux et ses proprietes dynamiques intrinseques comme son impedance caracteristique et son nombre d'onde complexe. Enfin, le quatrieme probleme porte sur le developpement d'une nouvelle methode de transmission exacte a 3 microphones applicable a des materiaux ou systemes symetriques ou non. Dans le cas symetrique, on montre que cette approche permet une nette amelioration de la caracterisation des proprietes dynamiques intrinseques d'un materiau. Mots cles. materiaux poreux, tube d'impedance, transmission sonore, absorption sonore, impedance acoustique, symetrie, porosite, matrice de transfert.

Observation unit management of acute decompensated heart failure.

PubMed

Schrock, Jon W; Emerman, Charles L

2009-01-01

Acute decompensated heart failure (ADHF) is a common illness presenting to the emergency department (ED) that is amenable to observation unit (OU) treatment. As the number of baby boomers continues to grow and the incidence of heart failure increases, the financial implications of ADHF treatment will become more prominent. Obtaining institutional support and developing a good working relationship with cardiology colleagues is vital to creating workable ADHF protocols for whichever type of OU an institution decides to use.

Absolute parameters and chemical composition of the binary star OU Gem

NASA Astrophysics Data System (ADS)

Glazunova, L. V.; Mishenina, T. V.; Soubiran, C.; Kovtyukh, V. V.

2014-10-01

The absolute parameters and chemical composition of the BY Dra-type spectroscopic binary OU Gem (HD 45088) were determined on the basis of 10 high-resolution spectra. A new orbital solution of the binary system was determined, the binary ephemerides were specified, and the main physical and atmospheric parameters of the binary components were obtained. The chemical composition of both components was estimated for the first time for the stars of such type.

Boundary Layer Simulation and Control in Wind Tunnels

DTIC Science & Technology

1988-04-01

de l’art dans le domaine de la simulation de la couche limite, ou le nombre de Reynolds n’est pas ou ne peut pas etre simule, examine les effets ...pour la definition de certains essais en soufflerie oil les effets visqueux sont d’une importance particuliere. CONTENTS Page PREFACE iii 1...transition associated with cylindrical bodies at high incidence in subsonic flow. Other relevant references are given therein. Figures 11 a-b, from Ref

Conference Proceedings of Energy Absorption of Aircraft Structures as an Aspect Crashworthiness (66th) Held in Luxembourg on 1-6 May 1988

DTIC Science & Technology

1988-12-01

efforts dans les f~murs ou dans la colonne vert~brale. 2.1.3. Jauges 11 peut s’agir de jauges simples, doubles ou de rosettes 3 directions. Les jauges ...34, -acc~l~rombtres mannequin en "classe 180", -efforts en "classe 180", - jauges en "classe 180", -r~sultantes efforts en "classe 180", -sommes des

La prise en charge des morsures de chien chez les enfants

PubMed Central

Sabhaney, Vikram; Goldman, Ran D.

2012-01-01

Résumé Question Une fillette de 4 ans jouait avec le chien de ses voisins. Le chien s’est excité et a mordu la jeune fille à l’avant-bras, y laissant une plaie punctiforme. À cause cette blessure, elle s’est présentée à mon bureau. Devrais-je la traiter avec des antibiotiques? Quel antibiotique faut-il utiliser et pendant combien de temps? Réponse L’administration d’antibiotiques prophylactiques est indiquée lorsqu’on a procédé à une suture primitive de la morsure, que la plaie est de gravité modérée à sévère, qu’elle est punctiforme (particulièrement s’il y a eu pénétration de l’os, de la gaine tendineuse ou de l’articulation), pour les morsures au visage, aux mains, aux pieds ou aux parties génitales ou lorsque les victimes sont immunodéprimées ou souffrent d’asplénisme. L’antibiotique de première intention est l’amoxicilline-clavulanate. La prophylaxie appropriée antitétanique et contre la rage devrait faire partie des soins chez un patient qui a été mordu par un chien, tout comme le débridement local et le nettoyage complet de la plaie.

The Third Place in Second Life: Real Life Community in a Virtual World

NASA Astrophysics Data System (ADS)

Peachey, Anna

In June 2006 The Open University (OU) purchased its first land in Second LifeTM (SL). Over a two and a half year period, the OU presence evolved and grew to a point where an average of between 150 and 250 unique users in any 7-day period are active in an OU area. This chapter charts the history of the development of the OU Second Life social community and considers the nature of that activity at a point of critical change, in January 2009, shortly before a new island is developed to provide a permanent home for the community. In order for the community to continue evolving it is necessary to understand the nature of the core activities of these users, and to consider this in a context of sustainable development. Through reference to aspects of socialisation and physical community, the author proposes that a virtual world environment can be described using the physical world concept of a Third Place in the information age, and considers the value of virtual space to a learning community. From a perspective of ethnography, this chapter captures a community development within SL and proposes that physical world concepts of community and Third Place are exhibited in a virtual world, and that there are equivalent benefits in the sense of support and belonging to a virtual world community.

Recommandations sur l’examen pelvien de dépistage systématique

PubMed Central

Tonelli, Marcello; Gorber, Sarah Connor; Moore, Ainsley; Thombs, Brett D.

2016-01-01

Résumé Objectif Examiner les lignes directrices de 2014 de l’American College of Physicians (ACP) en matière d’examens pelviens de dépistage du cancer (autre que du col), des maladies inflammatoires pelviennes ou d’autres affections gynécologiques bénignes afin de déterminer si les lignes directrices de l’ACP en matière d’examens pelviens systématiques sont conformes aux normes établies par le Groupe d’étude canadien sur les soins de santé préventifs (GECSSP) et peuvent être adaptées ou adoptées. Méthodologie La méthode SNAP-IT (Smooth National Adaptation and Presentation of Guidelines to Improve Thrombosis Treatment) a servi à déterminer si les lignes directrices de l’ACP étaient conformes aux normes du GECSSP et pouvaient être adaptées ou adoptées. Recommandations Le GECSSP recommande de ne pas effectuer un examen pelvien de dépistage des cancers non cervicaux, des maladies inflammatoires pelviennes ou d’autres affections gynécologiques chez les femmes asymptomatiques. Il s’agit d’une forte recommandation reposant sur des données probantes de qualité modérée. Conclusion Le GECSSP adopte la recommandation en matière d’examen pelvien de dépistage, comme publiée par l’ACP en 2014.

Monticello Mill Tailings Site Operable Unit III Annual Groundwater Report May 2014 Through April 2015, October 2015

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nguyen, Jason; Smith, Fred

This report provides the annual analysis of water quality restoration progress, cumulative through April 2015, for Operable Unit (OU) III, surface water and groundwater, of the U.S. Department of Energy (DOE) Office of Legacy Management Monticello Mill Tailings Site (MMTS). The MMTS is a Comprehensive Environmental Response, Compensation, and Liability Act National Priorities List site located in and near the city of Monticello, San Juan County, Utah. MMTS comprises the 110-acre site of a former uranium- and vanadium-ore-processing mill (mill site) and 1,700 acres of surrounding private and municipal property. Milling operations generated 2.5 million cubic yards of waste (tailings)more » from 1942 to 1960. The tailings were impounded at four locations on the mill site. Inorganic constituents in the tailings drained from the impoundments to contaminate local surface water (Montezuma Creek) and groundwater in the underlying alluvial aquifer. Mill tailings dispersed by wind and water also contaminated properties surrounding and downstream of the mill site. Remedial actions to remove and isolate radiologically contaminated soil, sediment, and debris from the former mill site (OU I) and surrounding properties (OU II) were completed in 1999 with the encapsulation of the wastes in an engineered repository located on DOE property 1 mile south of the former mill site. Contamination of groundwater and surface water remains within OU III at levels that exceed water quality protection standards. Uranium is the primary contaminant of concern. LM implemented monitored natural attenuation with institutional controls as the OU III remedy in 2004. Because groundwater restoration proceeded more slowly than expected and did not meet performance criteria established in the OU III Record of Decision (June 2004), LM implemented a contingency action in 2009 by an Explanation of Significant Difference to include a pump-and-treat system using a single extraction well and treatment by zero-valent iron (ex-situ treatment system). The contingency action was optimized in 2015 with the installation of 8 extraction wells and 16 monitoring wells in a focused area of the aquifer (area of attainment). Contaminated water is treated by solar evaporation at an existing onsite LM facility. Environmental monitoring at OU III consists of twice-yearly (April and October) collection and analysis of hydrologic and water-quality data from an established network of observation wells, seeps, and surface water locations. The scope of monitoring was expanded in 2009 for the ex situ treatment system and in 2015 for the remedy optimization system. Operation and monitoring of the ex situ treatment system was discontinued in 2014 with the start-up of the remedy optimization system. No data anomalies for OU III water quality trending or restoration progress are identified for the May 2014 through April 2015 reporting period. Although some regions of the aquifer demonstrate decreasing concentration trends, such trending is not evident for the bulk of the aquifer and a prolonged restoration period is indicated. The groundwater contingency remedy optimization system captures significant contaminant mass (primarily uranium) from the area of attainment; however, because that system only became operational in 2015, a long-term forecast of restoration progress is premature.« less

Mise à jour sur la prévention et le dépistage selon l’âge à l’intention des médecins de soins primaires canadiens

PubMed Central

Shimizu, Tawnya; Bouchard, Manon; Mavriplis, Cleo

2016-01-01

Résumé Objectif Faire la synthèse des meilleures lignes directrices fondées sur des données probantes concernant la prévention et le dépistage chez les adultes canadiens selon l’âge. Qualité des données Les recommandations du Groupe d’étude canadien sur les soins de santé préventifs représentent la source principale des renseignements et sont complétées par les recommandations pertinentes du Preventive Services Task Force des États-Unis lorsque celles du Groupe d’étude canadien étaient inaccessibles ou désuètes. Les guides de pratique des principales organisations nationales axées spécifiquement sur une maladie ou une spécialité ont aussi fait l’objet d’une révision pour prendre en compte les données factuelles les plus récentes. Message principal Les interventions de dépistage recommandées selon l’âge et le sexe sont présentées dans un tableau de synthèse où est mise en évidence la qualité des données à l’appui de ces recommandations. Un exemple de modèle à suivre dans les dossiers médicaux électroniques ou sur papier est aussi proposé. Conclusion Qu’il s’agisse d’une visite consacrée à la prévention ou d’une occasion saisie autrement de faire du counseling et du dépistage de prévention chez leurs patients, les médecins de soins primaires peuvent se servir de cette synthèse des recommandations fondées sur des données probantes pour maximiser leur efficience et prévenir d’importantes omissions ou des dépistages inutiles.

Evaluation of Head Mounted and Head Down Information Displays During Simulated Mine-Countermeasures Dives to 42 msw

DTIC Science & Technology

2008-04-01

visualisation tête basse (VTB) ou d’un visiocasque pour l’exécution de leurs tâches courantes sous l’eau. Neuf plongeurs de lutte contre les mines ont...existe peu d’information empirique sur l’aptitude des plongeurs à utiliser un dispositif multifonction de visualisation tête basse (VTB) ou d’un...experiment, the diver was also linked to the researchers and operations crew via audio communications. 11 Display Screen Chamber Laptop Diver

Standardisation for C2-Simulation Interoperation

DTIC Science & Technology

2015-11-01

la continuité du MSG-048 a permis, grâce notamment à la contribution de la communauté opérationnelle, de consolider le besoin et d’approfondir un...demandes de documents STO, RTO ou AGARD doivent comporter la dénomination « STO », « RTO » ou « AGARD » selon le cas, suivi du numéro de série. Des ...disponibilité des rapports de la STO au fur et à mesure de leur publication, vous pouvez consulter notre site Web

Remedial Investigation/Feasibility Study, Operable Unit 5, Elmendorf AFB, Anchorage, Alaska. Volume 1. Text

DTIC Science & Technology

1994-03-04

4.7a Organic Con mnats Detected in Upper Aquifer Groundwater .......... 4-46 4.7b Organic Contaminants Detected in Upper Aquifer Groundwater...OU 5 con ~tamiats and impacts on Ship Creek; "* Deftrmine fth fluenc of uppadient contminant sources on fth OU 5 "* Collect suifficient data to detemin...Post Rood, mnorh of the gdof course pro shop, and flowed into a drainage ditch parallel to Post Road. 0 All six source areas have undergone previous inv

Notes on the genus Conanalus Tinkham, 1943 (Orthoptera: Tettigoniidae: Conocephalinae) with one new species from Yunnan, China.

PubMed

Du, Bao-Jie; Song, Qiong; Shi, Fu-Ming

2015-06-05

The paper describes one new species, i.e. Conanalus bilobus sp. nov., and provides additional information on Conanalus brevicaudus Shi, Mao & Ou, 2008 (including female description for the first time), and Conanalus robustus Shi, Mao & Ou, 2008 from Yunnan, as well as illustrations of important morphological characters of Conanalus axinus Shi, Wang & Fu, 2005. A distribution map of the species of Conanalus from Yunnan, China is presented. The type material is deposited in the Museum of Hebei University.

Compounding Elastomers for Use in Armament Applications

DTIC Science & Technology

1977-02-01

Identlly by block number) A commercial masterbatch of a phosphonitrilic polymer proved to be much easier to mill-mix than the gum elastomer itself...1 and 2, respectively. The PNF200 masterbatch was much easier to work with than was the polymer itself. However, incorporation of 10 pphr of...Eiry- masterbatch 6 6 6 Stabilizer I form from 2 2 2 Graphite 1 Firestone 5 5 5 SE-33 —’ 5 5 5 Vul-Cup R o.u O.U 0.4 HI Sll 233 5 10

Angiossarcoma mimetizando endoleak tardio pós-reparo endovascular de aneurisma de aorta infrarrenal: relato de caso

PubMed Central

de Almeida, Bruno Lorenção; Caria, Vinicius Pena; Cavalcante, Sthefanie Fauve Andrade; Ventin, Felipe Carvalho; Vieira, Eduardo Augusto Moreira; Darold, Eduardo Mulinari; de Souza, Rodrigo Américo Cunha; Araújo, Edmur Carlos

2017-01-01

Resumo Em todo paciente submetido a reparo endovascular do aneurisma de aorta abdominal (REVA) que se apresente subitamente com quadro de dor abdominal ou sinais de choque, a hipótese de endoleak ou vazamento, com expansão do aneurisma e ruptura deve ser aventada. Apresentamos o caso de um paciente em pós-operatório de REVA que apresentou uma neoplasia de duodeno mimetizando um endoleak. PMID:29930672

Total petroleum systems of the Grand Erg/Ahnet Province, Algeria and Morocco; the Tanezzuft-Timimoun, Tanezzuft-Ahnet, Tanezzuft-Sbaa, Tanezzuft Mouydir, Tanezzuft-Benoud, and Tanezzuft-Bechar/Abadla

USGS Publications Warehouse

Klett, T.R.

2000-01-01

Undiscovered, conventional oil and gas resources were assessed within total petroleum systems of the Grand Erg/Ahnet Province (2058) as part of the U.S. Geological Survey World Petroleum Assessment 2000. The majority of the Grand Erg/ Ahnet Province is in western Algeria; a very small portion extends into Morocco. The province includes the Timimoun Basin, Ahnet Basin, Sbaa Basin, Mouydir Basin, Benoud Trough, Bechar/Abadla Basin(s), and part of the Oued Mya Basin. Although several petroleum systems may exist within each of these basins, only seven ?composite? total petroleum systems were identified. Each total petroleum system occurs in a separate basin, and each comprises a single assessment unit. The main source rocks are the Silurian Tanezzuft Formation (or lateral equivalents) and Middle to Upper Devonian mudstone. Maturation history and the major migration pathways from source to reservoir are unique to each basin. The total petroleum systems were named after the oldest major source rock and the basin in which it resides. The estimated means of the undiscovered conventional petroleum volumes in total petroleum systems of the Grand Erg/ Ahnet Province are as follows: [MMBO, million barrels of oil; BCFG, billion cubic feet of gas; MMBNGL, million barrels of natural gas liquids] Total Petroleum System MMBO BCFG MMBNGL Tanezzuft-Timimoun 31 1,128 56 Tanezzuft-Ahnet 34 2,973 149 Tanezzuft-Sbaa 162 645 11 Tanezzuft-Mouydir 12 292 14 Tanezzuft-Benoud 72 2,541 125 Tanezzuft-Bechar/Abadla 16 441 22

Séroprévalence et facteurs associés à l’acceptation du Conseil et Dépistage Volontaire du VIH chez l’enfant à Lubumbashi, République Démocratique du Congo

PubMed Central

Ngwej, Dieudonné Tshikwej; Mukuku, Olivier; Malonga, Françoise Kaj; Luboya, Oscar Numbi; Kakoma, Jean-Baptiste Sakatolo; Wembonyama, Stanis Okitotsho

2017-01-01

Résumé Introduction Malgré le dépistage du VIH proposé lors de la naissance ou au cours des consultations préscolaires, la proportion des enfants qui croissent ou décèdent sous statut sérologique au VIH inconnu est importante en République Démocratique du Congo (RDC). L’objectif de cette étude était de déterminer la séroprévalence au cours d’un dépistage volontaire et d’identifier les facteurs associés à l’acceptation du conseil et dépistage du VIH (CDV) en dehors de la maladie ou de toute exposition au VIH dans une population pédiatrique à Lubumbashi, RDC. Méthodes Il s’agissait d’une étude prospective transversale à visée analytique menée du 1er août 2006 au 31 septembre 2007. Elle avait été réalisée dans 4 centres communautaires de CDV répartis dans 4 zones de santé de la ville de Lubumbashi en RDC (Lubumbashi, Ruashi, Kampemba et de Kenya). L’étude avait consisté à faire le dépistage volontaire du VIH chez les enfants de moins de 15 ans. Les caractéristiques sociodémographiques et les paramètres relatifs au conseil et dépistage volontaire ont été étudiés. Les analyses statistiques descriptives usuelles et une régression logistique ont été réalisées. Résultats Sur 463 enfants dépistés du VIH, 41 (8,9%; IC 95%: 6,5%-11,9%) ont été testés positifs. L’acceptation du conseil et dépistage volontaire du VIH en dehors de la maladie ou de l’exposition au VIH était significativement plus élevée lorsque l’enfant était âgé de plus de 2 ans (Odds ratio ajusté (ORa) = 3,6 [IC 95%: 1,1-12,2]), lorsque le statut sérologique du VIH des parents était négatif ou inconnu (ORa = 27,4 [IC 95%: 9,4-80,0]), lorsque l’un ou l’autre ou les deux parents biologiques étaient en vie (ORa = 24,9 [IC 95%: 2,4-250,8]) et lorsque la connaissance du lieu de dépistage était fait par des moyens autres que le professionnel de santé (ORa = 2,9 [IC 95%: 1,0-7,9]). Conclusion Notre étude montre une forte prévalence du VIH chez les enfants justifiant la nécessité de réaliser le CDV qui est significativement accepté par leurs parents et tuteurs dans la ville de Lubumbashi. PMID:29255552

Diffraction des neutrons : principe, dispositifs expérimentaux et applications

NASA Astrophysics Data System (ADS)

Muller, C.

2003-02-01

La diffraction de neutrons, sur monocristal ou sur échantillon polycristallin (ou poudre), est une technique très largement utilisée, en science des matériaux comme en biologie, lorsque l'on souhaite déterminer la structure cristalline d'un composé ou d'une molécule. Toutefois, le degré de précision de la détermination structurale est très corrélé au choix de l'instrument utilisé. Il s'en suit que la question “comment choisir l'instrument le mieux adapté au composé et à la problématique ?" apparaît comme fondamentale. L'objectif de ce cours est de tenter de répondre à cette question en décrivant brièvement les caractéristiques instrumentales de différents diffractomètres, en exposant les avantages spécifiques des expériences de diffraction de neutrons et en donnant quelques exemples d'application.

Generalized quantum interference of correlated photon pairs

PubMed Central

Kim, Heonoh; Lee, Sang Min; Moon, Han Seb

2015-01-01

Superposition and indistinguishablility between probability amplitudes have played an essential role in observing quantum interference effects of correlated photons. The Hong-Ou-Mandel interference and interferences of the path-entangled photon number state are of special interest in the field of quantum information technologies. However, a fully generalized two-photon quantum interferometric scheme accounting for the Hong-Ou-Mandel scheme and path-entangled photon number states has not yet been proposed. Here we report the experimental demonstrations of the generalized two-photon interferometry with both the interferometric properties of the Hong-Ou-Mandel effect and the fully unfolded version of the path-entangled photon number state using photon-pair sources, which are independently generated by spontaneous parametric down-conversion. Our experimental scheme explains two-photon interference fringes revealing single- and two-photon coherence properties in a single interferometer setup. Using the proposed interferometric measurement, it is possible to directly estimate the joint spectral intensity of a photon pair source. PMID:25951143

Final Hazard Categorization for the Remediation of Six 300-FF-2 Operable Unit Solid Waste Burial Grounds

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. D. Ludowise

2006-12-12

This report provides the final hazard categorization (FHC) for the remediation of six solid waste disposal sites (referred to as burial grounds) located in the 300-FF-2 Operable Unit (OU) on the Hanford Site. These six sites (618-1, 618-2, 618-3, 618-7, 618-8, and 618-13 Burial Grounds) were determined to have a total radionuclide inventory (WCH 2005a, WCH 2005d, WCH 2005e and WCH 2006b) that exceeds the DOE-STD-1027 Category 3 threshold quantity (DOE 1997) and are the subject of this analysis. This FHC document examines the hazards, identifies appropriate controls to manage the hazards, and documents the FHC and commitments for themore » 300-FF-2 Burial Grounds Remediation Project.« less

100-OL-1 Operable Unit Pilot Study: XRF Evaluation of Select Pre-Hanford Orchards

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bunn, Amoret L.; Fritz, Brad G.; Pulsipher, Brent A.

Prior to the acquisition of land by the U.S. Department of War in February 1943 and the creation of the Hanford Site, the land along the Columbia River was home to over 1000 people. Farming and orchard operations by both homesteaders and commercial organizations were prevalent. Orchard activities and the associated application of lead arsenate pesticide ceased in 1943, when residents were moved from the Hanford Site at the beginning of the Manhattan Project. Today, the residues from historical application of lead arsenate pesticide persist in some locations on the Hanford Site. In 2012, the U.S. Department of Energy, U.S.more » Environmental Protection Agency, and Washington State Department of Ecology established the 100-OL-1 Operable Unit (OU) through the Hanford Federal Facility Agreement and Consent Order, known as the Tri-Party Agreement. The pre-Hanford orchard lands identified as the 100-OL-1 OU are located south of the Columbia River and east of the present-day Vernita Bridge, and extend southeast to the former Hanford townsite. The discontinuous orchard lands within 100-OL-1 OU are approximately 20 km2 (5000 ac). A pilot study was conducted to support the approval of the remedial investigation/feasibility study work plan to evaluate the 100-OL-1 OU. This pilot study evaluated the use of a field portable X-ray fluorescence (XRF) analyzer for evaluating lead and arsenic concentrations on the soil surface as an indicator of lead arsenate pesticide residues in the OU. The objectives of the pilot study included evaluating a field portable XRF analyzer as the analytical method for decision making, estimating the nature and extent of lead and arsenic in surface soils in four decision units, evaluating the results for the purpose of optimizing the sampling approach implemented in the remedial investigation, and collecting information to improve the cost estimate and planning the cultural resources review for sampling activities in the remedial investigation. Based on the results of the pilot study, the recommendations for the revision of the work plan are as follows: • characterize the surface soil using field portable XRF measurements with confirmatory inductively coupled plasma mass spectroscopy sampling for the remedial investigation • establish decision units of similar defined areas • establish a process for field investigation of soil concentrations exceeding the screening criteria at the border of the 100-OL-1 OU • define data quality objectives for the work plan using the results of the pilot study and refining the sampling approach for the remedial investigation.« less

Characterizing Macro Scale Patterns Of Uncertainty For Improved Operational Flood Forecasting Over The Conterminous United States

NASA Astrophysics Data System (ADS)

Vergara, H. J.; Kirstetter, P.; Gourley, J. J.; Flamig, Z.; Hong, Y.

2015-12-01

The macro scale patterns of simulated streamflow errors are studied in order to characterize uncertainty in a hydrologic modeling system forced with the Multi-Radar/Multi-Sensor (MRMS; http://mrms.ou.edu) quantitative precipitation estimates for flood forecasting over the Conterminous United States (CONUS). The hydrologic model is centerpiece of the Flooded Locations And Simulated Hydrograph (FLASH; http://flash.ou.edu) real-time system. The hydrologic model is implemented at 1-km/5-min resolution to generate estimates of streamflow. Data from the CONUS-wide stream gauge network of the United States' Geological Survey (USGS) were used as a reference to evaluate the discrepancies with the hydrological model predictions. Streamflow errors were studied at the event scale with particular focus on the peak flow magnitude and timing. A total of 2,680 catchments over CONUS and 75,496 events from a 10-year period are used for the simulation diagnostic analysis. Associations between streamflow errors and geophysical factors were explored and modeled. It is found that hydro-climatic factors and radar coverage could explain significant underestimation of peak flow in regions of complex terrain. Furthermore, the statistical modeling of peak flow errors shows that other geophysical factors such as basin geomorphometry, pedology, and land cover/use could also provide explanatory information. Results from this research demonstrate the utility of uncertainty characterization in providing guidance to improve model adequacy, parameter estimates, and input quality control. Likewise, the characterization of uncertainty enables probabilistic flood forecasting that can be extended to ungauged locations.

Les ruptures traumatiques du tendon quadricipital: à propos de 3 cas

PubMed Central

Benyass, Youssef; Chafry, Bouchaib; Koufagued, Kaldadak; Bouabid, Salim; Chagar, Belkacem

2015-01-01

Les ruptures traumatiques du tendon quadricipital sont rares, elles surviennent préférentiellement après 40 ans, suite à un traumatisme indirect chez le sportif (flexion contrariée du genou) ou traumatisme banal chez le sédentaire. La tendinopathie préexistante est fréquente. La rupture est le plus souvent totale et siège au corps du tendon 60% des cas ou décallotement quadricipital au bord supérieur de la rotule (40% des cas). Le diagnostic est essentiellement clinique. Les examens complémentaires (échographie et imagerie par résonance magnétique) sont utiles et appuient le diagnostique, mais sont souvent faussement rassurants hormis la radiographie qui montre une rotule basse. Le traitement essentiellement chirurgical associé à la rééducation fonctionnelle donne des résultats largement meilleurs. Le délai d'intervention est un facteur pronostic très important. Les auteurs rapportent 03cas de rupture de tendon quadricipital. L’âge moyen est de 50ans. Ils ont été traités chirurgicalement et revus régulièrement, avec un recul de 16 mois pour apprécier l’évolution. Les résultats ont été très bons chez 02 cas et bon chez 01 cas. L'amélioration a été très nette selon les critères: marche, douleur et reprise d'activité physique. PMID:26985261

Monitoring of pile composting process of OFMSW at full scale and evaluation of odour emission impact.

PubMed

Gutiérrez, M C; Martín, M A; Serrano, A; Chica, A F

2015-03-15

In this study, the evolution of odour concentration (ouE/m(3)STP) emitted during the pile composting of the organic fraction of municipal solid waste (OFMSW) was monitored by dynamic olfactometry. Physical-chemical variables as well as the respirometric variables were also analysed. The aim of this work was twofold. The first was to determine the relationship between odour and traditional variables to determine if dynamic olfactometry is a feasible and adequate technique for monitoring an aerobic stabilisation process (composting). Second, the composting process odour impact on surrounding areas was simulated by a dispersion model. The results showed that the decrease of odour concentration, total organic carbon and respirometric variables was similar (around 96, 96 y 98% respectively). The highest odour emission (5224 ouE/m(3)) was reached in parallel with the highest microbiological activity (SOUR and OD20 values of 25 mgO2/gVS · h and 70 mgO2/gVS, respectively). The validity of monitoring odour emissions during composting in combination with traditional and respirometric variables was demonstrated by the adequate correlation obtained between the variables. Moreover, the quantification of odour emissions by dynamic olfactometry and the subsequent application of the dispersion model permitted making an initial prediction of the impact of odorous emissions on the population. Finally, the determination of CO2 and CH4 emissions allowed the influence of composting process on carbon reservoirs and global warming to be evaluated. Copyright © 2014 Elsevier Ltd. All rights reserved.

Entity Profiling for Intelligence Using the Graphical Overview of Social and Semantic Interactions of People (GOSSIP) Software Tool

DTIC Science & Technology

2010-11-01

TR 2010-188; R & D pour la défense Canada – Toronto; Novembre 2010. Introduction ou contexte : En règle générale, l’analyste du renseignement ou...model humans Series3 DRDC Toronto TR 2010-188 13 Figure 4. continued. Profiles for famous names generated by subjects and the model...document is classified) 13 . ABSTRACT (A brief and factual summary of the document. It may also appear elsewhere in the body of the document itself. It is

Trombo flutuante em veia femoral

PubMed Central

Bertanha, Matheus; Pimenta, Rafael Elias Farres; Brandão, Gustavo Muçouçah Sampaio; Sobreira, Marcone Lima; Moura, Regina; Jaldin, Rodrigo Gibin; de Camargo, Paula Angeleli Bueno; Yoshida, Winston Bonetti

2017-01-01

Resumo O trombo venoso flutuante em veia femoral é um tipo de trombo com alto potencial de embolização pulmonar. Entretanto, ainda é controversa a conduta mais apropriada nesses casos. Tratamentos clínicos com anticoagulantes ou fibrinolíticos e trombectomias abertas ou por meio de dispositivos endovasculares vêm sendo empregados ainda sem um critério de indicação bem definido. Apresentamos três casos clínicos de trombos flutuantes em veia femoral, de etiologias distintas, cujos tratamentos e respectivas evoluções serão discutidos. PMID:29930666

Technical Status Review on Drag Prediction and Analysis from Computational Fluid Dynamics: State of the Art

DTIC Science & Technology

1989-06-01

Methodes de Panel) ct sur l’equation complete du potentiel avec ou sans incorporation des effets visqueux. sont couramment employees darn l’industrie...quo pour ce qui eat do Is privision do Is tralnie ia situation actuolle nett pas satisfaisante. Il est en effet plus facile d’obtonir do bonnos...d’un nouvel appareil civil ou militairo utilisont donc encore largaent les essais en soufflerie en Is1 C. minimum eat ensuite corrigE des effets

Methode d’Identification des Forces Aerodynamiques Instationnaires sur les Essais en Vol, Validation Experimentale (Method of Mathematical Identification of Unsteady Airloads From Flight Measurements, Experimental Validation)

DTIC Science & Technology

2000-05-01

gage en vol de rdponses de jauges de contraintes en responses in maneuver, illustrated by an example manoeuvre, illustrd par un exemple issu de la coming...sous ddrapage, ... , braquages gouvernes,..) la forme: -Les mesures sont directement les rkponses de - minimiser Z = Q(k - Xj tb) 2 jauges de...3, la rdponse - les facteurs de ponddration des mesures, fli ou incidence de l’avion, la rdponse de la jauge plus ou momns subjectifs, sont remplacds

The dating of the fourth volume of Guillaume-Antoine Olivier’s “Entomologie, ou histoire naturelle des insectes”

PubMed Central

Bousquet, Yves

2018-01-01

Abstract Despite the title page is dated 1795, the fourth volume of Olivier’s Entomologie, ou histoire naturelle des insectes was issued in two parts, one probably in 1795 and the second in 1800. All new taxa made available in this work have previously been dated 1795 in the literature. A list of new species described in 1795 and a list of those that have to be dated 1800 are appended. The genus Necrobia should be credited to Latreille, 1797, not Olivier, 1795. PMID:29674858

The dating of the fourth volume of Guillaume-Antoine Olivier's "Entomologie, ou histoire naturelle des insectes".

PubMed

Bousquet, Yves

2018-01-01

Despite the title page is dated 1795, the fourth volume of Olivier's Entomologie, ou histoire naturelle des insectes was issued in two parts, one probably in 1795 and the second in 1800. All new taxa made available in this work have previously been dated 1795 in the literature. A list of new species described in 1795 and a list of those that have to be dated 1800 are appended. The genus Necrobia should be credited to Latreille, 1797, not Olivier, 1795.

AGARD Flight Test Techniques Series. Volume 17. Electronic Warfare Test and Evaluation. (Les Essais et l’Evaluation du Materiel de Guerre Electronique)

DTIC Science & Technology

2000-03-01

FRIENDLY DR ENEMY PLOY OFOR DEGSRADING, ENEUTALY IG DEGRA E,’ EUTRALIE, OR DESTR Y concepts, procedures, and techniques that apply generically to CMA...Association of Old Crows, September 1984 Price, Alfred, "The History of Electronic Warfare," Volume 2, Association of Old Crows, October 1989 Claxton, John...Canada Les demandes de documents RTO ou AGARD doivent comporter la denomination "RTO" ou "AGARD" selon le cas, suivie du numdro de s~rie (par exemple

Progress Toward Cleanup of Operable Unit 1 Groundwater at the US DOE Mound, Ohio, Site: Success of a Phase-Combined Remedy – 15310

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hooten, Gwendolyn; Cato, Rebecca; Looney, Brian

2015-03-01

Operable Unit 1 (OU-1) soil and groundwater have been affected by volatile organic compounds (VOC) Present groundwater remedy is collection, treatment, and disposal (pump and treat [P&T]) Several combinations of technologies were used to address soil and groundwater contamination Monitored natural attenuation (MNA) is a viable alternative Majority of source term has been excavated VOC concentrations in groundwater have decreased Attenuation mechanisms have been observed in the subsurface at OU-1

Superfund record of decision (EPA Region 9): Mather Air Force Base, Landfill Operable Unit, Sacramento County, CA, August 3, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This decision document presents the selected remedial actions for the Landfill OU Sites, at the inactive Mather AFB, Sacramento County, California. The Installation Restoration Program (IRP) sites which comprise the Landfill OU at the inactive Mather AFB include: Site 1 - Runway Overrun Landfill; Site 2 - `8150` Area Landfill; Site 3 - Northeast Perimeter Landfill No. 1; Site 4 - Northeast Perimeter Landfill No. 2; Site 5 - Northeast Perimeter Landfill No. 3; and Site 6 - Firing Range Landfill Sites.

Prise en charge des troubles de consommation d’opioïdes en première ligne

PubMed Central

Srivastava, Anita; Kahan, Meldon; Nader, Maya

2017-01-01

Résumé Objectif Conseiller les médecins quant aux options thérapeutiques à recommander à des populations précises de patients : approche axée sur l’abstinence, traitement d’entretien par la buprénorphine-naloxone ou traitement d’entretien par la méthadone. Sources d’information Une recherche sur PubMed a été effectuée, et on a relevé dans les publications les données sur l’efficacité, l’innocuité et le profil d’effets indésirables de l’approche axée sur l’abstinence, du traitement par la buprénorphine-naloxone et du traitement par la méthadone. Les études d’observation et interventionnelles ont été incluses. Message principal La méthadone et la buprénorphine-naloxone sont substantiellement plus efficaces que l’approche axée sur l’abstinence. La méthadone présente un taux de rétention plus élevé que la buprénorphine-naloxone, alors que la buprénorphine-naloxone présente un risque plus faible de surdose. Les médecins devraient recommander le traitement par la méthadone ou la buprénorphine-naloxone plutôt que l’approche axée sur l’abstinence, et ce, à tous les groupes de patients (données de niveau I). La méthadone est préférable à la buprénorphine-naloxone chez les patients qui présentent un risque élevé d’abandon, comme les usagers d’opioïdes par injection (données de niveau I). Les jeunes et les femmes enceintes qui font usage d’opioïdes par injection devraient aussi recevoir la méthadone d’abord (données de niveau III). Si la buprénorphine-naloxone est prescrite en premier, il faut faire passer rapidement le patient à la méthadone si les symptômes de sevrage, les fortes envies ou la consommation d’opioïdes persistent malgré une dose optimale de buprénorphine-naloxone (données de niveau II). La buprénorphine-naloxone est recommandée chez les usagers d’opioïdes sur ordonnance par voie orale socialement stables, surtout s’ils ont un emploi ou si leurs obligations familiales les empêchent de se rendre à la pharmacie tous les jours, s’ils ont une affection médicale ou psychiatrique exigeant des soins réguliers de première ligne (données de niveau IV), ou encore si leur emploi exige une fonction cognitive ou un rendement psychomoteur élevés (données de niveau III). La buprénorphine-naloxone est aussi recommandée chez les patients qui présentent un risque élevé de toxicité à la méthadone, tels que les personnes âgées, les personnes qui prennent de fortes doses de benzodiazépines ou d’autres sédatifs, les gros buveurs, les personnes dont la tolérance aux opioïdes est faible et les personnes à risque de prolongement de l’intervalle QT (données de niveau III). Conclusion Il faut tenir compte des caractéristiques et des préférences individuelles des patients lors de la sélection d’un traitement de première intention par un agoniste des opioïdes. Chez les patients qui présentent un risque élevé d’abandon (adolescents et patients socialement instables), la rétention en traitement doit avoir préséance sur les autres considérations cliniques. Chez les patients qui présentent un risque élevé de toxicité (comme les usagers abusifs d’alcool ou de benzodiazépines), la sécurité a sans doute préséance. Ce qu’il importe le plus de considérer toutefois, c’est que le traitement par un agoniste des opioïdes est beaucoup plus efficace que l’approche axée sur l’abstinence. PMID:28292811

Freestanding midwifery unit versus obstetric unit: a matched cohort study of outcomes in low-risk women

PubMed Central

Møller, Anna Margrethe; Fenger-Grøn, Morten; Knudsen, Lisbeth B; Sandall, Jane

2011-01-01

Objective To compare perinatal and maternal morbidity and birth interventions in low-risk women giving birth in two freestanding midwifery units (FMUs) and two obstetric units (OUs). Design A cohort study with a matched control group. Setting The region of North Jutland, Denmark. Participants 839 low-risk women intending FMU birth and a matched control group of 839 low-risk women intending OU birth were included at the start of care in labour. OU women were individually chosen to match selected obstetric/socio-economic characteristics of FMU women. Analysis was by intention to treat. Main outcome measures Perinatal and maternal morbidity and interventions. Results No significant differences in perinatal morbidity were observed between groups (Apgar scores <7/5, <9/5 or <7/1, admittance to neonatal unit, asphyxia or readmission). Adverse outcomes were rare and occurred in both groups. FMU women were significantly less likely to experience an abnormal fetal heart rate (RR: 0.3, 95% CI 0.2 to 0.5), fetal–pelvic complications (0.2, 0.05 to 0.6), shoulder dystocia (0.3, 0.1 to 0.9), occipital–posterior presentation (0.5, 0.3 to 0.9) and postpartum haemorrhage >500 ml (0.4, 0.3 to 0.6) compared with OU women. Significant reductions were found for the FMU group's use of caesarean section (0.6, 0.3 to 0.9), instrumental delivery (0.4, 0.3 to 0.6), and oxytocin augmentation (0.5, 0.3 to 0.6) and epidural analgesia (0.4, 0.3 to 0.6). Transfer during or <2 h after birth occurred in 14.8% of all FMU births but more frequently in primiparas than in multiparas (36.7% vs 7.2%). Conclusion Comparing FMU and OU groups, there was no increase in perinatal morbidity, but there were significantly reduced incidences of maternal morbidity, birth interventions including caesarean section, and increased likelihood of spontaneous vaginal birth. FMU care may be considered as an adequate alternative to OU care for low-risk women. Pregnant prospective mothers should be given an informed choice of place of birth, including information on transfer. PMID:22021892

Implementation of Enhanced Attenuation at the DOE Mound Site OU-1 Landfill: Accelerating Progress and Reducing Costs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hooten, Gwendolyn; Cato, Rebecca; Looney, Brian

At the US Department of Energy (DOE), Office of Legacy Management, Mound, Ohio, Site, chlorinated organic contaminants (cVOCs) originating from the former solid-waste landfill have impacted groundwater in Operable Unit 1 (OU-1). The baseline groundwater remedy was groundwater pump and treat (P&T). Since the source materials have been removed from the landfill, the Mound core team, which consists of DOE, US Environmental Protection Agency (US EPA), Ohio EPA, and other stakeholders, is assessing the feasibility of switching from the active P&T remedy to a passive attenuation-based remedy. Toward this end, an enhanced attenuation (EA) strategy based on the creation ofmore » structured geochemical zones was developed. This EA strategy addresses the residual areas of elevated cVOCs in soil and groundwater while minimizing the rebound of groundwater concentrations above regulatory targets (e.g., maximum contaminant levels [MCLs]) and avoiding plume expansion while the P&T system is turned off. The EA strategy has improved confidence and reduced risk on the OU-1 groundwater transition path to monitored natural attenuation (MNA). To better evaluate the EA strategy, DOE is conducting a field demonstration to evaluate the use of edible oils to enhance the natural attenuation processes. The field demonstration is designed to determine whether structured geochemical zones can be established that expedite the attenuation of cVOCs in the OU-1 groundwater. The EA approach at OU-1 was designed based on “structured geochemical zones” and relies on groundwater flow through a succession of anaerobic and aerobic zones. The anaerobic zones stimulate relatively rapid degradation of the original solvent source compounds (e.g., cVOCs such as tetrachloroethene [PCE] and trichloroethene [TCE]). The surrounding aerobic areas encourage relatively rapid degradation of daughter products (such as dichloroethene [DCE] and vinyl chloride [VC]) as well as enhanced cometabolism of TCE resulting from the utilization of methane and other reduced hydrocarbons that are formed and released from the anaerobic zones.« less

Remedial Investigation Work Plan for Upper East Fork Poplar Creek Operable Unit 3 at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee. Environmental Restoration Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-08-01

Upper East Fork Popular Creek Operable Unit 3 (UEFPC OU 3) is a source term OU composed of seven sites, and is located in the western portion of the Y-12 Plant. For the most part, the UEFPC OU 3 sites served unrelated purposes and are geographically removed from one another. The seven sites include the following: Building 81-10, the S-2 Site, Salvage Yard oil storage tanks, the Salvage Yard oil/solvent drum storage area, Tank Site 2063-U, the Salvage Yard drum deheader, and the Salvage Yard scrap metal storage area. All of these sites are contaminated with at least one ormore » more hazardous and/or radioactive chemicals. All sites have had some previous investigation under the Y-12 Plant RCRA Program. The work plan contains summaries of geographical, historical, operational, geological, and hydrological information specific to each OU 3 site. The potential for release of contaminants to receptors through various media is addressed, and a sampling and analysis plan is presented to obtain objectives for the remedial investigation. Proposed sampling activities are contingent upon the screening level risk assessment, which includes shallow soil sampling, soil borings, monitoring well installation, groundwater sampling, and surface water sampling. Data from the site characterization activities will be used to meet the above objectives. A Field Sampling Investigation Plan, Health and Safety Plan, and Waste Management Plan are also included in this work plan.« less

Dynamique moléculaire et canaux ioniques

NASA Astrophysics Data System (ADS)

Crouzy, S.

2005-11-01

Diffusion de neutrons et Dynamique Moléculaire (DM) sont deux techniques intimement liées car elles portent sur les mêmes échelles de temps: la première apporte des informations structurales ou dynamiques sur le système physique ou biologique, la seconde permet de décoder ces informations à travers un modèle facilitant l'interprétation des résultats. Au delà de l'intérêt que la technique de DM peut avoir en relation directe avec les neutrons, il est intéressant de comprendre comment les modèles sont construits et comment les techniques de simulation peuvent aller beaucoup plus loin que de simples modélisations. Nous décrirons brièvement, dans la suite de cet exposé, la technique de DM et les méthodes plus sophistiquées de calculs d'énergie libre et de potentiels de force moyenne à partir des simulations de DM. Puis nous verrons avec deux exemples tirés de nos travaux théoriques sur les canaux ioniques comment ces calculs peuvent nous donner accès à des vitesses de réaction ou des constantes d'affinité ou de liaison. La première étude porte sur un analogue de la gramicidine A qui forme un canal conducteur d'ions interrompus par le basculement d'un cycle dioxolane [1]. La seconde concerne le canal potassique KcsA dont nous avons étudié le blocage du coté extracellulaire par l'ion Tetra Ethyl Ammonium [2].

The gene expression profile of resistant and susceptible Bombyx mori strains reveals cypovirus-associated variations in host gene transcript levels.

PubMed

Guo, Rui; Wang, Simei; Xue, Renyu; Cao, Guangli; Hu, Xiaolong; Huang, Moli; Zhang, Yangqi; Lu, Yahong; Zhu, Liyuan; Chen, Fei; Liang, Zi; Kuang, Sulan; Gong, Chengliang

2015-06-01

High-throughput paired-end RNA sequencing (RNA-Seq) was performed to investigate the gene expression profile of a susceptible Bombyx mori strain, Lan5, and a resistant B. mori strain, Ou17, which were both orally infected with B. mori cypovirus (BmCPV) in the midgut. There were 330 and 218 up-regulated genes, while there were 147 and 260 down-regulated genes in the Lan5 and Ou17 strains, respectively. Gene ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment for differentially expressed genes (DEGs) were carried out. Moreover, gene interaction network (STRING) analyses were performed to analyze the relationships among the shared DEGs. Some of these genes were related and formed a large network, in which the genes for B. mori cuticular protein RR-2 motif 123 (BmCPR123) and the gene for B. mori DNA replication licensing factor Mcm2-like (BmMCM2) were key genes among the common up-regulated DEGs, whereas the gene for B. mori heat shock protein 20.1 (Bmhsp20.1) was the central gene among the shared down-regulated DEGs between Lan5 vs Lan5-CPV and Ou17 vs Ou17-CPV. These findings established a comprehensive database of genes that are differentially expressed in response to BmCPV infection between silkworm strains that differed in resistance to BmCPV and implied that these DEGs might be involved in B. mori immune responses against BmCPV infection.

Griffe cubitale d'origine lépreuse traitée par transfert tendineux de Lasso Zancolli: à propos d'un cas

PubMed Central

El Alaoui, Adil; Sbiyaa, Mouhcine; Bah, Aliou; Rabhi, Ilyas; mezzani, Amine; Marzouki, Amine; Boutayeb, Fawzi

2015-01-01

La lèpre est une maladie infectieuse due à une mycobactérie (M. Leprae, Bacille de Hansen, ou BH) dont le tropisme nerveux est destructeur pour les cellules de Schwann. La localisation préférentielle des neuropathies tronculaire secondaire à la lèpre restent dominé par les zones ou les troncs nerveux traversent les défilés ostéo-ligamentaires inextensibles comme le défilé rétro-épitrochléen ou passe le nerf ulnaire. De nombreux travaux ont été consacrés à la souffrance nerveuse secondaire à la lèpre et surtout l'atteinte du nerf ulnaire qui se manifeste par une griffe des doigts. Le traitement dans ce cas est palliatif et fait appel à plusieurs techniques décrites dans la littérature. Nous rapportons dans ce travail un cas de griffe cubitale chez un patient lépreux traité par transfert tendineux de Lasso Zancolli. PMID:26985277

Slug Test Characterization Results for Multi-Test/Depth Intervals Conducted During the Drilling of CERCLA Operable Unit OU UP-1 Wells 299-W19-48, 699-30-66, and 699-36-70B

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spane, Frank A.; Newcomer, Darrell R.

2010-06-15

This report presents test descriptions and analysis results for multiple, stress-level slug tests that were performed at selected test/depth intervals within three Operable Unit (OU) UP-1 wells: 299-W19-48 (C4300/Well K), 699-30-66 (C4298/Well R), and 699-36-70B (C4299/Well P). These wells are located within, adjacent to, and to the southeast of the Hanford Site 200-West Area. The test intervals were characterized as the individual boreholes were advanced to their final drill depths. The primary objective of the hydrologic tests was to provide information pertaining to the areal variability and vertical distribution of hydraulic conductivity with depth at these locations within the OUmore » UP-1 area. This type of characterization information is important for predicting/simulating contaminant migration (i.e., numerical flow/transport modeling) and designing proper monitor well strategies for OU and Waste Management Area locations.« less

Slug Test Characterization Results for Multi-Test/Depth Intervals Conducted During the Drilling of CERCLA Operable Unit OU ZP-1 Wells 299-W11-43, 299-W15-50, and 299-W18-16

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spane, Frank A.; Newcomer, Darrell R.

2010-06-21

The following report presents test descriptions and analysis results for multiple, stress level slug tests that were performed at selected test/depth intervals within three Operable Unit (OU) ZP-1 wells: 299-W11-43 (C4694/Well H), 299-W15-50 (C4302/Well E), and 299-W18-16 (C4303/Well D). These wells are located within south-central region of the Hanford Site 200-West Area (Figure 1.1). The test intervals were characterized as the individual boreholes were advanced to their final drill depths. The primary objective of the hydrologic tests was to provide information pertaining to the areal variability and vertical distribution of hydraulic conductivity with depth at these locations within the OUmore » ZP-1 area. This type of characterization information is important for predicting/simulating contaminant migration (i.e., numerical flow/transport modeling) and designing proper monitor well strategies for OU and Waste Management Area locations.« less

Engine Fluid Leakage Detection: A Feasibility Study

DTIC Science & Technology

2011-07-01

2011 © Sa Majesté la Reine (en droit du Canada), telle que représentée par le ministre de la Défense nationale, 2011 DRDC Atlantic TM 2011-050 i... de détecter tout problème possible lié à la sécurité ou aux performances des moteurs à turbine à gaz d’aéronefs. Le signalement immédiat d’une fuite...carburant ou d’huile moteur nuisent non seulement aux performances d’un moteur, mais elles représentent également une menace réelle pour la sécurité de

Chinese-English Rocketry Dictionary. Volume 3

DTIC Science & Technology

1979-03-01

xiezhen diania 14] Q i. plate tank 1’? yangil yanghuara $, anodic oxidation process 18 yangji yinji dianya I3 A.j - I t anode -cathode voltage...talo Gu Yin yin aao ou Ylng Yin ta’u Ou YU You taluan cuan Yuing Yawg talui cul 341 tau tm yuan ruan toa ’Wg Cown Yft ye. tfu tu Yfln t’tian tuant...tanhuang Jiahe mopian 94f X laE f(4 ’m’. #j spring-loaded membrane 14 tanhuang Jiaju A1 A -)t spring clawp 15 tanhuang Jianshendian A1 &c A V -’P spring

Toxoplasmose oculaire atypique chez une femme congolaise de 72 ans: à propos d'une observation

PubMed Central

Bienvenu, Yogolelo Asani; Angel, Musau Nkola; Eric, Kasamba Ilunga; Socrate, Kapalu Mwangala; Sebastien, Mbuyi Musanzayi; Philippe, Cilundika Mulenga; Leon, Kabamba Ngombe; Bruno, Iye Ombamba Kayimba; Gaby, Chenge Borasisi

2015-01-01

Les auteurs rapportent un cas de toxoplasmose oculaire binoculaire, rarement décrit dans la littérature, chez une personne âgée de 72 ans, de sexe féminin, à laquelle s'associe une rétinite pigmentaire unilatérale. Cette observation permet d'attirer l'attention de la communauté scientifique sur les autres formes ou variétés de présentation moins courantes, « atypiques », pouvant être rencontrées ou associées à la toxoplasmose oculaire. PMID:26958130

Spatial two-photon interference in a Hong-Ou-Mandel interferometer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Heonoh; Kwon, Osung; Kim, Wonsik

2006-02-15

We report the observation of the cosine modulation in the coincidence rates from a Hong-Ou-Mandel (HOM) interferometer. Spatial interference fringes are seen by minute rotations of one mirror about the vertical axis, while the beam splitter is fixed in the center position. The results show that the maximum visibility of the fringe is 0.81, and the photon pairs separated by less than 1.52 mm in the source plane are measured to be indistinguishable. It turns out that it is possible to invert the HOM dips to peaks by the rotation of the mirror.

[Epidemiological profile, clinical and therapeutic cutaneous leishmaniasis in the Department of Dermatology at University Hospital in Ouagadougou, Burkina Faso].

PubMed

Bamba, S; Barro-Traoré, F; Drabo, M K; Gouba, A; Traoré, A; Guiguemdé, T R

2013-01-01

It is a retrospective study in the Service of Dermatology at the University Hospital Center Yalgado Ouédraogo of Ouagadougou (C.H.U.-YO). This study aimed to list the leishmaniasis clinical cases reported in the registers of this department from January 1999 to December 2007. In total, 251 leishmaniasis clinical cases have been reported. The hospital prevalence was 1,1%. Women represented 53% versus 47% men. The average age of patients was 22,78 ans +/- 121. The most frequent clinical forms were those often crusted (40.2%), papulo ulcerative (16.7%) and papulonodular (13.9%). Lesions most often sat on the lower limbs (33%) and thoracic limbs (45%). On the therapeutic level, the first line treatment meglumine antimonite (Glucantime) accounted for only 25.9% of prescriptions.

Corrosion-Control (CC) Program: Pilot Powder Coating Station Service Test.

DTIC Science & Technology

1986-03-14

o CL oU C4 CL00 z ;,S Go 0 m~ CL - C9 uj4 U..~D o . ZC.F Go zz 2 0 I- - c t < m U, cc V V4 cg c ~ D GD...Spray Booth# Curing Oven and A2-58 UNIT TOTAL is_18 A2-1 1WOW - o 0 -1 Q S re. 10 U c Z. 2E E. a.E 8 tE 20 4AU ==- %A a 4 $AO - Lo 48 0 w 0 -IL .. 0.... 0...Laa 00 3-r Q’ IA E zo 0..0 -< 4o C a) Ia - o x c bi. l c *4 ’a a~~* coLo. 0V Ua- 41 w - a V 2 2 .8 h A a U to bo co i ac

Variable phenotypic expressivity in inbred retinal degeneration mouse lines: A comparative study of C3H/HeOu and FVB/N rd1 mice.

PubMed

van Wyk, Michiel; Schneider, Sabine; Kleinlogel, Sonja

2015-01-01

Recent advances in optogenetics and gene therapy have led to promising new treatment strategies for blindness caused by retinal photoreceptor loss. Preclinical studies often rely on the retinal degeneration 1 (rd1 or Pde6b(rd1)) retinitis pigmentosa (RP) mouse model. The rd1 founder mutation is present in more than 100 actively used mouse lines. Since secondary genetic traits are well-known to modify the phenotypic progression of photoreceptor degeneration in animal models and human patients with RP, negligence of the genetic background in the rd1 mouse model is unwarranted. Moreover, the success of various potential therapies, including optogenetic gene therapy and prosthetic implants, depends on the progress of retinal degeneration, which might differ between rd1 mice. To examine the prospect of phenotypic expressivity in the rd1 mouse model, we compared the progress of retinal degeneration in two common rd1 lines, C3H/HeOu and FVB/N. We followed retinal degeneration over 24 weeks in FVB/N, C3H/HeOu, and congenic Pde6b(+) seeing mouse lines, using a range of experimental techniques including extracellular recordings from retinal ganglion cells, PCR quantification of cone opsin and Pde6b transcripts, in vivo flash electroretinogram (ERG), and behavioral optokinetic reflex (OKR) recordings. We demonstrated a substantial difference in the speed of retinal degeneration and accompanying loss of visual function between the two rd1 lines. Photoreceptor degeneration and loss of vision were faster with an earlier onset in the FVB/N mice compared to C3H/HeOu mice, whereas the performance of the Pde6b(+) mice did not differ significantly in any of the tests. By postnatal week 4, the FVB/N mice expressed significantly less cone opsin and Pde6b mRNA and had neither ERG nor OKR responses. At 12 weeks of age, the retinal ganglion cells of the FVB/N mice had lost all light responses. In contrast, 4-week-old C3H/HeOu mice still had ERG and OKR responses, and we still recorded light responses from C3H/HeOu retinal ganglion cells until the age of 24 weeks. These results show that genetic background plays an important role in the rd1 mouse pathology. Analogous to human RP, the mouse genetic background strongly influences the rd1 phenotype. Thus, different rd1 mouse lines may follow different timelines of retinal degeneration, making exact knowledge of genetic background imperative in all studies that use rd1 models.

Neuropsychiatric symptoms of the elderly with Alzheimer's disease and the family caregivers' distress.

PubMed

Storti, Luana Baldin; Quintino, Débora Teles; Silva, Natália Michelato; Kusumota, Luciana; Marques, Sueli

2016-08-15

to analyze the relationship between the distress of the family caregiver and the presence of neuropsychiatric symptoms in elderly patients with Alzheimer's disease or mixed dementia. a descriptive, cross-sectional study conducted in the Geriatric and Dementias Clinic of a general tertiary hospital, with 96 elderly people with Alzheimer's disease or mixed dementia and their family caregivers. Questionnaires to characterize the elderly and caregivers, and the Neuropsychiatric Inventory were used. Descriptive statistics and Pearson correlation test were performed. 68.7% of the elderly were women, average age 80.8 years, 56.2% had Alzheimer's disease and 43.7%, mixed dementia. Among caregivers, 90.6% were women, average age 56, 70.8% took care of parents and 64.6% lived with the elderly. There was a strong (r = 0.82) and significant (p <0.01) correlation between the total score on the Neuropsychiatric Inventory and the total score on the Neuropsychiatric Inventory-Distress and strong (r = 0.80) and significant (p <0 01) correlation between the total score on the Neuropsychiatric Inventory Distress and the number of neuropsychiatric symptoms, i.e., the higher the number, frequency and severity of these symptoms in the elderly, the more intense is the caregiver distress. the presence of neuropsychiatric symptoms in the elderly was related to increased distress in caregivers. analisar a relação entre o desgaste do cuidador familiar e a presença de sintomas neuropsiquiátricos em idosos com doença de Alzheimer ou demência mista. estudo descritivo, transversal, realizado no Ambulatório de Geriatria e Demências de um Hospital Geral Terciário, com 96 idosos com doença de Alzheimer ou demência mista e seus cuidadores familiares. Foram utilizados o questionário para caracterização dos idosos e cuidadores e o Inventário Neuropsiquiátrico. Foram realizadas estatísticas descritivas e o teste de correlação de Pearson. 68,7% dos idosos eram mulheres, média de idade 80,8 anos, 56,2% possuíam doença de Alzheimer e 43,7%, demência mista. Dos cuidadores, 90,6% eram mulheres, média de idade 56 anos, 70,8% cuidavam do pai/mãe e 64,6% moravam com o idoso. Houve correlação forte (r=0,82) e significativa (p<0,01) entre o escore total do Inventário Neuropsiquiátrico e o escore total do Inventário Neuropsiquiátrico Desgaste e correlação forte (r=0,80) e significativa (p<0,01) entre o escore total do Inventário Neuropsiquiátrico Desgaste e o número de sintomas neuropsiquiátricos, ou seja, quanto maiores o número, a frequência e a gravidade destes sintomas nos idosos maior é o desgaste do cuidador. a presença dos sintomas neuropsiquiátricos nos idosos apresentou relação com maior desgaste nos cuidadores. analizar la relación entre el desgaste del cuidador familiar y la presencia de síntomas neuropsiquiátricos en pacientes ancianos con enfermedad de Alzheimer o demencia mixta. estudio descriptivo, transversal, realizado en la clínica de Geriatría y Demencias de un hospital general terciario, con 96 ancianos con enfermedad de Alzheimer o demencia mixta y sus cuidadores familiares. Se utilizaron cuestionarios para caracterizar los ancianos y cuidadores y el Inventario Neuropsiquiátrico. Se realizaron estadísticas descriptivas y prueba de correlación de Pearson. el 68,7% de los ancianos eran mujeres, con una edad promedio de 80,8 años, el 56,2% tenían enfermedad de Alzheimer y el 43,7%, demencia mixta. Entre los cuidadores, el 90,6% eran mujeres, con una media de 56 años, el 70,8% se hacía cargo del padre / madre y el 64,6% vivía con los ancianos. Hubo una fuerte (r = 0,82) y significativa (p <0,01) correlación entre la puntuación total en el Inventario Neuropsiquiátrico y la puntuación total en el Inventario Neuropsiquiátrico-Desgaste y fuerte correlación (r = 0,80) y significativa (p <0 01) entre la puntuación total en el Inventario Neuropsiquiátrico-Desgaste y el número de síntomas neuropsiquiátricos, es decir, cuanto mayor sea el número, la frecuencia y la severidad de estos síntomas en los ancianos, mayor es el desgaste del cuidador. la presencia de síntomas neuropsiquiátricos en los ancianos estaban relacionados con un mayor desgaste en los cuidadores.

Acceptabilité du test VIH proposé aux nourrissons dans les services pédiatriques, en Côte d'Ivoire, Significations pour la couverture du diagnostic pédiatrique

PubMed Central

Oga, Maxime; Brou, Hermann; Dago-Akribi, Hortense; Coffie, Patrick; Amani-Bossé, Clarisse; Ékouévi, Didier; Yapo, Vincent; Menan, Hervé; Ndondoki, Camille; Timité-Konan, M.; Leroy, Valériane

2014-01-01

Résumé Problème: Le dépistage VIH chez les enfants a rarement été au centre des préoccupations des chercheurs. Quand le dépistage pédiatrique a retenu l'attention, cela a été pour éclairer seulement sur les performances diagnostiques en ignorant même que le test pédiatrique comme bien d'autres peut s'accepter ou se refuser. Cet article met au cœur de son analyse les raisons qui peuvent expliquer qu'on accepte ou qu'on refuse de faire dépister son enfant. Objectif: Etudier chez les parents, les mères, les facteurs explicatifs de l'acceptabilité du test VIH des nourrissons de moins de six mois. Méthodes: Entretien semi-directif à passages répétés avec les parents de nourrissons de moins de six mois dans les formations sanitaires pour la pesée/vaccination et les consultations pédiatriques avec proposition systématique d'un test VIH pour leur nourrisson. Résultats: Nous retenons que la réalisation effective du test pédiatrique du VIH chez le nourrisson repose sur trois éléments. Primo, le personnel de santé par son discours (qui dénote de ses connaissances et perceptions même sur l'infection) orienté vers les mères influence leur acceptation ou non du test. Secundo, la mère qui par ses connaissances et perceptions même sur le VIH, dont le statut particulier, l'impression de bien-être chez elle et son enfant influence toute réalisation du test pédiatrique VIH. Tertio, l'environnement conjugal de la mère, particulièrement caractérisé par les rapports au sein du couple, sur la facilité de parler du test VIH et sa réalisation chez les deux parents ou chez la mère seulement sont autant de facteurs qui influencent la réalisation effective du dépistage du VIH chez l'enfant. Le principe préventif du VIH, et le désir de faire tester l'enfant ne suffisent pas à eux seuls pour aboutir à sa réalisation effective, selon certaines mères confrontées au refus du conjoint. A l'opposé, les autres mères refusant la réalisation du test pédiatrique disent s'y opposer ; bien entendu, même dans le cas où le conjoint l'accepterait. Discussion: Les mères sont les principales mises en cause et craignent les réprimandes et la stigmatisation. Le père, le conjoint peut être un obstacle, quand il s'oppose au test VIH du nourrisson, ou devenir le facilitateur de sa réalisation s'il est convaincu. Le positionnement du père demeure donc essentiel dans la question de l'acceptabilité du VIH pédiatrique. Les mères en ont conscience et présagent des difficultés à faire dépister ou non les enfants sans avis préalable du conjoint à la fois père, et chef de famille. Conclusion: La question du dépistage pédiatrique du VIH, au terme de notre analyse, met en face trois éléments qui exigent une gestion globale pour assurer une couverture effective. Ces trois éléments n'existeraient pas sans s'influencer, donc ils sont constamment en interaction et empêchent ou favorisent la réalisation ou non du test pédiatrique. Aussi, dans une intention d'aboutir à une couverture effective du dépistage VIH des nourrissons, faut-il tenir compte d'une gestion harmonieuse de ces trois éléments: La première, la mère seule (avec ses connaissances, ses perceptions), son environnement conjugal (de proposition du test intégrant 1- l’époux et / ou père de l'enfant avec ses perceptions et connaissances sur l'infection 2- la facilité de parler du test et sa réalisation chez les deux ou un des parents, la mère) et les connaissances, attitudes et pratiques du personnel de l’établissement sanitaire sur l'infection du VIH. Recommandations: Nos recommandations proposent une redéfinition de l'approche du VIH/sida vers des familles exposées au VIH et une intégration plus accentuée du père facilitant leur propre acceptation du test VIH et celle de leur enfant. PMID:25088574

Déprescrire les inhibiteurs de la pompe à protons

PubMed Central

Farrell, Barbara; Pottie, Kevin; Thompson, Wade; Boghossian, Taline; Pizzola, Lisa; Rashid, Farah Joy; Rojas-Fernandez, Carlos; Walsh, Kate; Welch, Vivian; Moayyedi, Paul

2017-01-01

Résumé Objectif Formuler des lignes directrices fondées sur les données probantes pour aider les cliniciens à décider du moment et de la façon sécuritaire de réduire la dose des inhibiteurs de la pompe à protons (IPP) ou d’en arrêter le traitement; se concentrer sur le niveau le plus élevé des données disponibles et obtenir les commentaires des professionnels de première ligne durant le processus de rédaction, de révision et d’adoption des lignes directrices. Méthodologie L’équipe était formée de 5 professionnels de la santé (1 médecin de famille, 3 pharmaciens et 1 gastro-entérologue) et de 5 membres sans droit de vote; les membres ont divulgué tout conflit d’intérêts. Le processus d’élaboration des lignes directrices a eu recours à l’approche GRADE (Grading of Recommendations Assessment, Development and Evaluation), de même qu’à un examen minutieux des données probantes dans le cadre de rencontres en personne, au téléphone et en ligne. Particulièrement, le processus d’élaboration des lignes directrices a inclus une revue systématique d’essais portant sur la déprescription des IPP et un examen de comptes rendus sur les torts liés à l’emploi continu des IPP. Les synthèses narratives sur les préférences des patients ainsi que les publications traitant des répercussions sur les ressources ont éclairé les recommandations. L’équipe a peaufiné le texte sur le contenu et les recommandations des lignes directrices par consensus, et a synthétisé les considérations cliniques afin de répondre aux questions courantes des cliniciens de première ligne. Une version préliminaire des lignes directrices a été distribuée aux cliniciens, puis aux associations de professionnels de la santé aux fins d’examen, et des révisions ont été apportées au texte à chaque étape. Un algorithme d’appui décisionnel a été conçu de concert avec les lignes directrices. Recommandations Les présentes lignes directrices recommandent de déprescrire les IPP (réduire la dose, mettre fin au traitement ou passer à l’administration « sur demande ») chez les adultes qui ont terminé un traitement d’au moins 4 semaines avec un IPP contre le pyrosis, l’œsophagite ou le reflux gastro-œsophagien léger à modéré, et dont les symptômes sont disparus. Les recommandations ne s’appliquent pas aux patients atteints ou qui ont déjà été atteints de l’œsophage de Barrett, d’une œsophagite grave de stade C ou D, ou d’antécédents connus d’ulcères gastro-intestinaux hémorragiques. Conclusion Les présentes lignes directrices émettent des recommandations pratiques pour décider du moment et de la façon de réduire la dose des inhibiteurs de la pompe à protons (IPP) ou d’en arrêter le traitement. Elles visent à contribuer au processus de décision conjointement avec le patient et non à dicter la décision.

Primary Mitral Valve Regurgitation Outcome in Patients With Severe Aortic Stenosis 1 Year After Transcatheter Aortic Valve Implantation: Echocardiographic Evaluation.

PubMed

Florentino, Thiago Marinho; Bihan, David Le; Abizaid, Alexandre Antonio Cunha; Cedro, Alexandre Vianna; Corrêa, Amably Pessoa; Santos, Alexandre Roginski Mendes Dos; Souza, Alexandre Costa; Bignoto, Tiago Costa; Sousa, José Eduardo Moraes Rego; Sousa, Amanda Guerra de Moraes Rego

2017-07-10

Mitral valve regurgitation (MR), present in up to 74% of the patients with severe aortic stenosis (AS), can be a negative prognostic factor when moderate or severe. The outcome of MR after percutaneous transcatheter aortic valve implantation (TAVI) and predictors associated with that outcome have not been well established in the literature. To assess the outcome of primary MR in patients submitted to TAVI and to identify associated factors. Observational study of patients with symptomatic severe AS submitted to TAVI from January 2009 to April 2015 at two specialized centers. Echocardiographic outcome was assessed with data collected before and 1 year after TAVI. Of the 91 patients with MR submitted to TAVI and followed up for at least 12 months, 67 (73.6%) had minimum/mild MR before the procedure and 24 (26.4%) had moderate/severe MR. Of those with minimum/mild MR, 62 (92.5%) had no change in the MR grade (p < 0.001), while 5 (7.5%) showed worsening. Of those with moderate/severe MR, 8 (33.3%) maintained the same grade and 16 (66.7%) improved it (p = 0.076). Patients with moderate/severe MR who improved MR grade had lower EuroSCORE II (p = 0.023) and STS morbidity (p = 0.027) scores, as compared to those who maintained the MR grade. MR grades change after TAVI. This study suggests a trend towards improvement in moderate/severe MR after TAVI, which was associated with lower preoperative risk scores. A insuficiência valvar mitral (IM), presente em até 74% dos pacientes com estenose aórtica (EA) grave, pode representar um fator prognóstico negativo quando moderada ou importante. A evolução da IM após implante percutâneo de valva aórtica transcateter (TAVI) e preditores associados a essa evolução não estão bem estabelecidos na literatura. Avaliar a evolução da IM primária em pacientes submetidos ao TAVI e identificar fatores associados a essa evolução. Realizou-se um estudo observacional em pacientes com EA grave sintomática, submetidos ao TAVI no período de janeiro de 2009 a abril de 2015 em dois centros especializados. Foram avaliados desfechos ecocardiográficos com dados antes e 1 ano após a intervenção. Dos 91 pacientes com IM que realizaram TAVI e tinham acompanhamento de pelo menos 12 meses, 67 (73,6%) apresentavam IM mínima ou discreta antes da realização do procedimento e 24 (26,4%), IM moderada ou grave. Entre os com IM mínima ou discreta, 62 (92,5%) não apresentaram mudança no grau de refluxo (p < 0,001) e 5 (7,5%) tiveram piora. Entre os com IM moderada ou grave, 8 (33,3%) permaneceram na mesma classe e 16 (66,7%) tiveram melhora (p = 0,076). Pacientes com IM moderada ou grave que melhoraram o grau de insuficiência apresentavam menores valores de EuroSCORE II (p = 0,023) e STS morbidade (p = 0,027), quando comparados aos que continuaram na mesma classe. Observou-se mudança significativa no grau de IM após realização de TAVI. Este estudo sugere uma tendência de melhora da IM moderada ou grave após TAVI, o que se associou a escores de risco pré-operatórios menos elevados.

Effectiveness of soil conservation strategies on erosion in Morocco

NASA Astrophysics Data System (ADS)

Benmansour, Moncef; Mabit, Lionel; Moussadek, Rachid; Yassin, Mohamed; Nouira, Asmae; Zouagui, Anis; Mrabet, Rachid; Iaaich, Hamza; Hajib, Said

2016-04-01

- In Morocco, reducing soil erosion and land degradation is a national priority for improving soil quality and protecting downstream water quality and quantity. The combined use of Cs-137 and Be-7 techniques permit to estimate long and short term erosion and deposition magnitudes under different agro-environment and climatic conditions and then to evaluate the effectiveness of soil conservation practices. Case studies using Cs-137 and Be-7 were carried out in three Moroccan agricultural sites: Marchouch, Harchane and Oued Mellah located in Rabat, Tétouan and Chaouia-Ouardigha regions, respectively. In these sites, fallout Cs-137 measurements allowed a retrospective assessment of long term (50-60 years) soil redistribution rates while fallout Be-7 (half-life of 53 days) was used to document short term soil erosion associated with rainfall events for different tillage systems and land uses. Long term soil erosion rates of the three regions evaluated by the Cs-137 method, ranged from 8 to 58 t/ha/yr. Mostly located in the upslope part of the fields, the eroding zones represented more than 70% of the total area. For the experimental sites in Rabat and Tétouan, the results obtained using Be-7 indicated that soil loss has been reduced significantly under no-till as compared to conventional tillage. Indeed, soil erosion rates were lowered by 50% for the Marchouch site and by 40% for the Harchane site. Concerning the Oued Mellah watershed, the results highlighted that high density Atriplex plantations have reduced soil loss by approximately 60 to 80%, while for the site under fruit plantations and cereals, soil erosion has been decreased by 58%.

Behavioral Perceptions of Oakland University Female College Students towards Human Papillomavirus Vaccination

PubMed Central

2016-01-01

Human Papillomavirus (HPV) vaccination decreases the risk for cervical cancer. However, the uptake of HPV vaccine remains low when compared with other recommended vaccines. This study evaluates the knowledge and attitudes towards HPV infection and vaccination, and the readiness for the uptake of HPV vaccine amongst female students attending Oakland University (OU) in Michigan, United States. This is a cross-sectional study targeting a randomized sample of a 1000 female OU students using an online questionnaire. The data were statistically analyzed using SPSS software. A total of 192 female students, with the mean age of 24 years completed the survey. The majority of participants had previous sexual experience with occasional use of contraceptives (78.1%), were non-smokers (92.7%), and non-alcohol drinkers (54.2%). The participants had a mean knowledge score of 53.0% with a standard error of 2.3% translating to a moderately informed population. The majority agreed that HPV is life threatening (79%), the vaccine prevents cervical cancer (62%), and that side effects would not deter them from vaccination (63%). Although two thirds (67%) believed that, based on sexual practices in the United States, female college students in Michigan have a higher chance of contracting HPV, about 50% did not believe they themselves were at risk. Higher knowledge correlated with increased recommendation for the vaccine (correlation-factor 0.20, p = 0.005). Results suggested that the best predictor for improvement of vaccination was the awareness level and health education. This indicates a need for an educational intervention to raise awareness, increase HPV vaccine uptake, and decrease the incidence of cervical cancer. PMID:27203284

Selected natural attenuation monitoring data, Operable Unit 1, Naval Undersea Warfare Center, Division Keyport, Washington, June 2001

USGS Publications Warehouse

Dinico, Richard Steven

2003-01-01

Previous investigations have shown that natural attenuation and biodegradation of chlorinated volatile organic compounds (CVOCs) are substantial in shallow ground water beneath the 9-acre former landfill at Operable Unit 1 (OU 1), Naval Undersea Warfare Center (NUWC), Division Keyport, Washington. The U.S. Geological Survey (USGS) has continued to monitor ground-water geochemistry to assure that conditions remain favorable for contaminant biodegradation. This report presents the ground-water geochemical and selected CVOC data collected at OU 1 by the USGS during June 11-14, 2001 in support of the long-term monitoring for natural attenuation. Overall, the June 2001 data indicate that redox conditions in the upper aquifer remain favorable for reductive dechlorination of CVOCs because strongly reducing conditions persisted beneath much of the former landfill. Redox conditions in the intermediate aquifer down gradient of the landfill appear to have become more favorable for reductive dechlorination because June 2001 dissolved hydrogen concentrations indicated strongly reducing conditions there for the first time. Although changes in redox conditions were observed at certain wells during 2001, a longer monitoring period is needed to ascertain if phytoremediation activities are affecting the ground-water chemistry. A minor change to future monitoring is proposed. Filtered organic carbon (previously referred to as dissolved, and defined as that which passes through a 0.45-micrometer membrane filter) should be analyzed in the future rather than unfiltered (previously referred to as total) organic carbon because the filtered analysis may be a better measure of bioavailable organic carbon. Unfiltered and filtered organic carbon data were collected during June 2001 for comparison. Filtered organic carbon data collected in the future could be reasonably compared with historical unfiltered organic carbon data by multiplying the historical data by a factor of about 0.9.

Grammaire de l’expérience romantique adolescente au Québec: une analyse sociosémantique des idéaux amoureux

PubMed Central

Blais, Martin; Hébert-Ratté, Roxanne; Hébert, Martine; Lavoie, Francine

2016-01-01

Cette étude vise à décrire, à travers les thèmes qu’évoque la plus belle expérience amoureuse chez de jeunes Québécois âgés de 14 à 19 ans, les formes sémantiques de l’amour contemporain ainsi que les attentes et les paradoxes dont elles témoignent sur le plan communicationnel. Au total, 6 961 jeunes Québécois âgés de 14 à 18 ans recrutés dans les milieux scolaires ont décrit leur plus belle expérience amoureuse vécue ou souhaitée. Une analyse des champs lexicaux, réalisée avec le logiciel Sémato, a permis de dégager six (6) formes sémantiques dominantes: 1) la fidélité, le respect et l’authenticité, 2) les références à la sensualité (embrasser et enlacement), 3) l’ancrage de l’amour idéal dans la compagnie de l’autre et des activités concrètes, 4) l’importance de la passion, de la magie (pour les deux genres) et, surtout pour les garçons, du plaisir, 5) l’ancrage de l’idéal amoureux dans des projets d’union et d’enfants, et 6) l’ancrage du couple dans des lieux précis, dans un quotidien ou des souvenirs tangibles. Ces formes sémantiques sont discutées en fonction des problèmes qu’elles ont pu résoudre et ceux qu’elles font émerger. Les différences de genre sont aussi discutées. PMID:27917004

Milan Army Ammunition Plant focused feasibility study for the northern industrial area soil. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Locandro, R.R.; Okusu, N.M.; Case, J.

1995-04-01

ICF Kaiser Engineers (ICF) and Environmental Resources Management (ERM) have been contracted by the US Army Environmental Center (USAEC) to perform a Focused Feasibility Study (FS) for contaminated soil within the northern industrial areas of Milan Army Ammunition Plant (MAAP), Tennessee. The purpose of the Focused FS is to develop and evaluate remedial alternatives such that an appropriate remedy can be selected for the site. The MAAP Remedial Investigation (RI) performed in 1989--1991 confirmed that the O-Line Ponds area, facility drainage ditches that received industrial wastewater, and manufacturing and disposal areas have been sources of groundwater contamination. One finding ofmore » the RI Report was that sufficient information was available concerning the O-Line Ponds area to proceed with a Focused FS. The O-Line Ponds area was further divided into two operable units (OUs): OU1 is the groundwater immediately downgradient of the O-Line Ponds area, and OU2 is the soil, surface water, and sediment at the O-Line Ponds area. A Proposed Plan and Record of Decision (ROD) for OU1 were finalized in 1992, which called for groundwater extraction, treatment, and reinjection of the treated water upgradient of the O-Line Ponds. The design of this system was completed in 1993, and construction of the system is currently underway. For OU2, the Proposed Plan and ROD (finalized in 1993) called for the extension of the existing multi-layered cap to cover the contaminated soil around the perimeter of the existing cap. The design of the cap extension was completed in 1994, and construction will begin in late 1994.« less

Influence of pH cycling on the microtensile bond strength of self-etching adhesives containing MDPB and fluoride to dentin and microhardness of enamel and dentin adjacent to restorations.

PubMed

Pedrosa, Vivianne Oliveira; Flório, Flávia Martão; Turssi, Cecília Pedroso; Amaral, Flávia Lucisano; Basting, Roberta Tarkany; França, Fabiana Mantovani

2012-12-01

To evaluate the influence of pH cycling on microtensile bond strength (µTBS) and fracture pattern of MDPB- and fluoride-containing self-etching adhesive systems to dentin, and on the cross-sectional Knoop microhardness (CSMH) of enamel and dentin adjacent to restorations. The two-step self-etching adhesive Clearfil SE Bond (SE; Kuraray), the two-step MDPBand fluoride-containing adhesive Clearfil Protect Bond (PB; Kuraray), and the one-step fluoride-containing adhesive One-Up Bond F Plus (OU; Tokuyama) were used to bond resin composite to midcoronal dentin surfaces (for µTBS testing) or to Class V cavities (for CSMH testing). µTBS and CSMH tests were performed after a 15-day period of pH cycling or storage in artificial saliva. µTBS to dentin was not affected by pH cycling or storage in artificial saliva; however, µTBS values found for PB were higher than those observed for OU. No difference existed among the µTBS values shown by PB, OU, and SE. The fracture pattern was affected by both pH cycling and adhesive system. In enamel, there was no difference in CSMH values provided by the different adhesive systems and storage media, regardless of the distance and depth from restoration. In dentin, PB and SE showed the highest CSMH values, which differed from those obtained for OU. Significantly higher CSMH values were found 100 µm from the restoration margin for all adhesive systems tested. The bond strength and microhardness in the vicinity of restorations were adhesive dependent, with MDPB and fluoride exerting no effect on the performance of the adhesive systems.

Provider-directed imaging stress testing reduces health care expenditures in lower-risk chest pain patients presenting to the emergency department.

PubMed

Miller, Chadwick D; Hoekstra, James W; Lefebvre, Cedric; Blumstein, Howard; Hamilton, Craig A; Harper, Erin N; Mahler, Simon; Diercks, Deborah B; Neiberg, Rebecca; Hundley, W Gregory

2012-01-01

Among intermediate- to high-risk patients with chest pain, we have shown that a cardiac magnetic resonance (CMR) stress test strategy implemented in an observation unit (OU) reduces 1-year health care costs compared with inpatient care. In this study, we compare 2 OU strategies to determine among lower-risk patients if a mandatory CMR stress test strategy was more effective than a physicians' ability to select a stress test modality. On emergency department arrival and referral to the OU for management of low- to intermediate-risk chest pain, 120 individuals were randomly assigned to receive (1) a CMR stress imaging test (n=60) or (2) a provider-selected stress test (n=60: stress echo [62%], CMR [32%], cardiac catheterization [3%], nuclear [2%], and coronary CT [2%]). No differences were detected in length of stay (median CMR=24.2 hours versus 23.8 hours, P=0.75), catheterization without revascularization (CMR=0% versus 3%), appropriateness of admission decisions (CMR 87% versus 93%, P=0.36), or 30-day acute coronary syndrome (both 3%). Median cost was higher among those randomly assigned to the CMR-mandated group ($2005 versus $1686, P<0.001). In patients with lower-risk chest pain receiving emergency department-directed OU care, the ability of a physician to select a cardiac stress imaging modality (including echocardiography, CMR, or radionuclide testing) was more cost-effective than a pathway that mandates a CMR stress test. Contrary to prior observations in individuals with intermediate- to high-risk chest pain, in those with lower-risk chest pain, these results highlight the importance of physician-related choices during acute coronary syndrome diagnostic protocols. URL: http://www.clinicaltrials.gov. Unique identifier: NCT00869245.

Use of Opioids in Latin America: The Need of an Evidence-Based Change.

PubMed

Rico, María Antonieta; Kraychete, Durval Campos; Iskandar, Aziza Jreige; Colimon, Frantz; Lara-Solares, Argelia; Cantisani, José Alberto Flores; Amescua-García, César; Núñez, María del Rocío Guillén; Bonilla, Patricia; Lech, Osvandré; Hernández-Castro, John Jairo; Guerrero, Carlos; Barrera, William Delgado; Gallegos, Manuel Sempértegui; Cook, María Berenguel; Garcia, João Batista Santos; Hernández, Concepción Pérez

2016-04-01

The subject of this publication has been focused on local considerations for facilitating regional best practice, including identifying and uniformly adopting the most relevant international guidelines on opioid use (OU) in chronic pain management. The Change Pain Latin America (CPLA) Advisory Panel conducted a comprehensive, robust, and critical analysis of published national and international reviews and guidelines of OU, considering those most appropriate for Latin America. A PubMed search was conducted using the terms "opioid," "chronic," and "pain" and then refined using the filters "practice guidelines" and "within the last 5 years" (2007-2012). Once the publications were identified, they were selected using five key criteria: "Evidence based," "Comprehensive," "From a well-recognized source," "Current publications," and "Based on best practice" and then critically analyzed considering 10 key criteria for determining the most relevant guidelines to be applied in Latin America. The initial PubMed search identified 177 reviews and guidelines, which was reduced to 16 articles using the five preliminary criteria. After a secondary analysis according to the 10 key criteria specific to OU in Latin America, 10 publications were selected for critical review and discussion. The CPLA advisory panel considered the "Safe and effective use of opioids for chronic non-cancer pain" (published in 2010 by the NOUGG of Canada) to be valid, relevant to Latin America, practical, evidence-based, concise, unambiguous, and sufficiently educational to provide clear instruction on OU and pain management and, thus, recommended for uniform adoption across the Latin America region. © 2015 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Remedial investigation/feasibility study of the Clinch River/Poplar Creek operable unit. Volume 1, main text

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This document is the combined Remedial Investigation/Feasibility Study (RI/FS) Report for the Clinch River/Poplar Creek Operable Unit (CR/PC OU), an off-site OU associated with environmental restoration activities at the U.S. Department of Energy (DOE) Oak Ridge Reservation (ORR). As a result of past, present, and potential future releases of hazardous substances into the environment, the ORR was placed on the National Priorities List in December 1989 (54 FR 48184). Sites on this list must be investigated for possible remedial action, as required by the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA, 42 U.S.C. 9601, et seq.). This report documentsmore » the findings of the remedial investigation of this OU and the feasibility of potential remedial action alternatives. These studies are authorized by Sect. 117 of CERCLA and were conducted in accordance with the requirements of the National Contingency Plan (40 CFR Part 300). DOE, the U.S. Environmental Protection Agency (EPA), and the Tennessee Department of Environment and Conservation (TDEC) have entered into a Federal Facility Agreement (FFA), as authorized by Sect. 120 of CERCLA and Sects. 3008(h) and 6001 of the Resource Conservation and Recovery Act (RCRA) (42 U.S.C. 6901, et seq.). The purpose of this agreement is to ensure a coordinated and effective response for all environmental restoration activities occurring at the ORR. In addition to other responsibilities, the FFA parties mutually define the OU boundaries, set remediation priorities, establish remedial investigation priorities and strategies, and identify and select remedial actions. A copy of this FFA is available from the DOE Information Resource Center in Oak Ridge, Tennessee.« less

Dynamique d'étalement

NASA Astrophysics Data System (ADS)

de Gennes, Pierre-Gilles

On analyse la progression d'un coin fiuide sur uo solide (dans le cas ou Tangle de contact thermodynamique θa est nul : regie d'Antonov satisfaite) en tenant compte des interactions Van der Waals a longue portee. On trouve : (a) un angle de contact apparent θa relie a la vitesse d'avancee U par θ^{3}_{a} ˜ U η/γ (η = viscosity, γ tension superficielle du liquide) d'ou une loi rayon/temps d'etalement pour une goutte r(t) 1/10. (b) un film precurseur ζ d'epaisseur ζ(x, f) decroissant asymptotiquement comme x1 ou x est la distance a la ligne triple. L'epaisseur h* d u film au voisinage de la ligne triple est h* a/θa (ou a est une distance atomique). Ceci permet de comprendre le fait (reconnu) que le film precurseur est bien visible seulement si l'angle de contact thermodynamique est nul. We analyse the shape of the liquid-air interface for a droplet spreading on a solid, in a regime where the Antonov rule is satisfied, taking into account the long range Van der Waals interactions between liquid and solid. We find: (a) an apparent contact angle θa related to the velocity U of the triple line by θ^{3}_{a} ˜ U η/γ (η = viscosity, γ surface tension of the liquid). This leads to a law of spreading (radius r/time t) for a droplet r t1/10. (b) a precursor film of thickness ζ, decreasing asymptotically like x-1, where x is the distance from the triple line. The thickness h* of the film at this line is h* a/θa where a is an atomic length: this explains why the precursor films are observed only when the thermodynamic contact angle vanishes.

Public health assessment for George Air Force Base, Victorville, San Bernardino County, California, Region 9: CERCLIS Number CA2570024453. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-12-01

George Air Force Base (AFB) is located in Victorville, California, in the Mojave Desert approximately 90 miles northeast of Los Angeles. Areas of concern at George AFB are divided into three operable units (OUs): Groundwater in the northeast portion of the base and adjacent off-site land is contaminated with volatile organic compounds, primarily TCE. A groundwater extraction and treatment system, designed to prevent migration of the contaminant plume towards the Mojave River, was completed in 1997. OU 1 also includes two other sites: SD-25, an industrial/storm drain, and WP-26, the former sewage treatment plant percolation ponds. Contaminated sediments and pipingmore » were removed from the storm drain at SD-25. A variety of leaks in this system resulted in an estimated of perhaps as much as a 750,000 to 800,000-gallon plume of jet propellant no. 4 (JP-4) encompassing an area of over 31 acres, as well as a dissolved-phase plume of benzene, toluene, ethylbenzene, and xylenes extending over an area of 121 acres. Because of OU2 plumes is almost completely covered by asphalt, and studies conducted thus far have not demonstrated significant migration of the plume, George AFB, state and federal regulators continue to evaluate the feasibility of natural attenuation as a possible cleanup strategy. This OU consists of the remaining Installation Restoration Program sites, includes old landfills, other dump and burial sites, munitions sites, fire training areas, and spill areas. In February 1997, George AFB completed a remedial investigation/feasibility study for OU 3.« less

Adverse Cardiovascular Effects with Acute Particulate Matter and Ozone Exposures: Interstrain Variation in Mice

PubMed Central

Hamade, Ali K.; Rabold, Richard; Tankersley, Clarke G.

2008-01-01

Objectives Increased ambient particulate matter (PM) levels are associated with cardiovascular morbidity and mortality, as shown by numerous epidemiology studies. Few studies have investigated the role of copollutants, such as ozone, in this association. Furthermore, the mechanisms by which PM affects cardiac function remain uncertain. We hypothesized that PM and O3 induce adverse cardiovascular effects in mice and that these effects are strain dependent. Study design After implanting radiotelemeters to measure heart rate (HR) and HR variability (HRV) parameters, we exposed C57Bl/6J (B6), C3H/HeJ (HeJ), and C3H/HeOuJ (OuJ) inbred mouse strains to three different daily exposures of filtered air (FA), carbon black particles (CB), or O3 and CB sequentially [O3CB; for CB, 536 ± 24 μg/m3; for O3, 584 ± 35 ppb (mean ± SE)]. Results We observed significant changes in HR and HRV in all strains due to O3CB exposure, but not due to sequential FA and CB exposure (FACB). The data suggest that primarily acute HR and HRV effects occur during O3CB exposure, especially in HeJ and OuJ mice. For example, HeJ and OuJ mice demonstrated dramatic increases in HRV parameters associated with marked brady-cardia during O3CB exposure. In contrast, depressed HR responses occurred in B6 mice without detectable changes in HRV parameters. Conclusions These findings demonstrate that important interstrain differences exist with respect to PM- and O3-induced cardiac effects. This interstrain variation suggests that genetic factors may modulate HR regulation in response to and recuperation from acute copollutant exposures. PMID:18709144

ShipMo3D Version 3.0 User Manual for Computing Ship Motions in the Time and Frequency Domains

DTIC Science & Technology

2012-01-01

permettent de modéliser un navire en manœuvre libre et en eau calme ou dans les vagues. SM3DBuildSeaway construit des modèles de voie maritime à trajet...manœuvrant libre - ment en eau calme ou dans une voie maritime modélisée. Plusieurs applications du logiciel ShipMo3D font des prévisions des mouvements de...can be produced. For a random seaway, the range of wave frequencies should be sufficient to encompass almost all energy within the wave spectrum. For

Pediatric Bilateral Blue Laser Pointer-Induced Maculopathy

PubMed Central

Raevis, Joseph; Shrier, Eric

2017-01-01

Background We report the first case of pediatric bilateral blue laser pointer maculopathy with complete resolution of visual symptoms. Case A 12-year-old boy presented with bilateral decreased visual acuity and central scotomata after blue laser pointer exposure. He was treated with a Medrol Dosepak and topical nonsteroidal anti-inflammatory drug (NSAID), with gradual visual acuity improved from 20/40 OU to 20/20 OU over 22 weeks, but with persistent evidence of outer retinal layer disruption from the external limiting membrane to the interdigitation zone. Conclusion Oral steroids and topical NSAIDs may be effective in improving visual outcomes in laser pointer maculopathy in the pediatric population. PMID:28611647

Final Environmental Assessment/Overseas Environmental Assessment Joint Strile Fighter System Development and Demonstration Developmental Test Program

DTIC Science & Technology

2007-01-01

tte r t es t a...ct iv iti es . Pr op os ed p er fo rm an ce te st s w ou ld c oi nc id e w ith F Q , f lu tte r, hi gh A ng le -o f- A tta ck ( A oA ), an...cl os el y in te gr at ed w ith th e FQ , f lu tte r, an d hi gh A oA te st s a nd w ou ld g en er al ly p ro ce ed in c on ce rt

Slug Test Characterization Results for Multi-Test/Depth Intervals Conducted During the Drilling of CERCLA Operable Unit OU ZP-1 Wells 299-W10-33 and 299-W11-48

DOE Office of Scientific and Technical Information (OSTI.GOV)

Newcomer, Darrell R.

2007-09-30

Slug-test results obtained from single and multiple, stress-level slug tests conducted during drilling and borehole advancement provide detailed hydraulic conductivity information at two Hanford Site Operable Unit (OU) ZP-1 test well locations. The individual test/depth intervals were generally sited to provide hydraulic-property information within the upper ~10 m of the unconfined aquifer (i.e., Ringold Formation, Unit 5). These characterization results complement previous and ongoing drill-and-test characterization programs at surrounding 200-West and -East Area locations (see Figure S.1).

On some factors affecting the nonstoichiometry in U 3O 8

NASA Astrophysics Data System (ADS)

Fujino, Takeo; Tagawa, Hiroaki; Adachi, Takeo

1981-03-01

The nonstoichiometry of U 3O 8 was studied under various conditions. The {O}/{U} atom ratios obtained by the oxidation of uranium metal in air followed by cooling with moderate rates (method 1) are 2.67 ± 0.01 in the temperature range 700 900°C and 2.662 ± 0.005 at 1000°C and are generally larger than the ratio by thermogravimetry. If the oxidation was carried out in a crucible with a lid, a compositional peak was observed at 900 950°C, which did not appear for the U 3O 8 samples from UO 2. The U 3O 8 made from UO 2 by method 1 have {O}/{U} ratios 2.655 ± 0.005 (700° C), 2.653 ± 0.004 (800° C), 2.648 ± 0.004 (900° C) and 2.645 ± 0.003 (1000° C). Differences were observed in the O/U ratios of heating and cooling series. X-ray diffraction analysis showed several additional peaks other than those of α-U 3O 8 for the samples which exhibited the compositional peak.

Transient hyperphosphatemia: a benign laboratory disorder in a boy with Gitelman syndrome.

PubMed

Skalova, Sylva; Kutilek, Stepan

2016-01-01

Transient hyperphosphatasemia of infancy and early childhood (THI) is characterized by transiently increased activity of serum alkaline phosphatase (S-ALP), predominantly its bone or liver isoform, in children under five years of age. There are no signs of metabolic bone disease or hepatopathy corresponding with the increased S-ALP. THI is benign disorder, rather laboratory than clinical disorder, which is usually accidentally detected in both healthy and sick children. When encountered in a child with either chronic bone, liver or kidney disease, it might concern the physician. We present a three year old boy with genetically confirmed Gitelman syndrome where THI was detected accidentally during periodic check-up. S-ALP peaked to 41.8 µkat/L, there were neither laboratory or clinical signs of liver or bone disease; the S-ALP dropped to normal value of 4 µkat/L 60 days later. Therefore, the patient fulfilled the criteria for THI. There were no further increases in S-ALP. Resumo A hiperfosfatasemia transitória benigna da infância (HTBI) é caracterizada por elevação transitória da atividade da fosfatase alcalina sérica (S-ALP), predominantemente em sua isoforma óssea ou hepática, em crianças com menos de cinco anos de idade. Não há sinais de patologia óssea metabólica ou hepatopatia correspondentes ao aumento da S-ALP. A HTBI é um distúrbio benigno, mais laboratorial que clínico, normalmente detectado acidentalmente em crianças saudáveis e acometidas por alguma patologia. Quando encontrada em crianças com doença crônica óssea, hepática ou renal, maiores preocupações são justificadas. O presente relato descreve o caso de um menino de três anos de idade com síndrome de Gitelman geneticamente confirmada, em que a HTBI foi detectada acidentalmente durante um exame periódico. A S-ALP atingiu o pico de 41,8 µkat/L, sem sinais laboratoriais ou clínicos de doença hepática ou óssea. O valor de S-ALP caiu para o nível normal de 4 µkat/L 60 dias mais tarde. Portanto, o paciente satisfazia os critérios para HTBI. Não houve outros aumentos na S-ALP.

MODELING TRANSPORT IN THE DOWN GRADIENT PORTION OF THE 200-PO-1 OPERABLE UNIT AT THE HANFORD SITE

DOE Office of Scientific and Technical Information (OSTI.GOV)

MEHTA S; ALY AH; MILLER CW

2009-12-03

Remedial Investigations are underway for the 200-PO-l Operable Unit (OU) at the U.S. Department of Energy's Hanford Site in Washington State. To support the baseline risk assessment and evaluation of remedial alternatives, fate and transport modeling is being conducted to predict the future concentration of contaminants of potential concern in the 200-PO-1 OU. This study focuses on modeling the 'down gradient' transport of those contaminants that migrate beyond the 3-D model domain selected for performing detailed 'source area' modeling within the 200-PO-1 OU. The down gradient portion is defined as that region of the 200-PO-1 OU that is generally outsidemore » the 200 Area (considered 'source area') of the Hanford Site. A 1-D transport model is developed for performing down gradient contaminant fate and transport modeling. The 1-D transport model is deemed adequate based on the inferred transport pathway of tritium in the past and the observation that most of the contaminant mass remains at or near the water table within the unconfined aquifer of the Hanford Formation and the Cold-Creek/Pre-Missoula Gravel unit. The Pipe Pathway feature of the GoldSim software is used to perform the calculations. The Pipe Pathway uses a Laplace transform approach to provide analytical solutions to a broad range of advection-dominated mass transport systems involving one-dimensional advection, longitudinal dispersion, retardation, decay and ingrowth, and exchanges with immobile storage zones. Based on the historical concentration distribution data for the extensive tritium plume in this area, three Pipe Pathways are deemed adequate for modeling transport of contaminants. Each of these three Pipe Pathways is discretized into several zones, based on the saturated thickness variation in the unconfined aquifer and the location of monitoring wells used for risk assessment calculation. The mass fluxes of contaminants predicted to exit the source area model domain are used as an input to the down gradient model, while the flow velocities applied are based on the present-day hydraulic gradients and estimation of hydraulic conductivity in the unconfined aquifer. The results of the calculation indicate that the future concentrations of contaminants of potential concern in the down gradient portion of the 200-PO-1 OU declines with time and distance.« less

Reply to "Comment on `Route from discreteness to the continuum for the Tsallis q -entropy' "

NASA Astrophysics Data System (ADS)

Oikonomou, Thomas; Bagci, G. Baris

2018-06-01

It has been known for some time that the usual q -entropy Sq(n ) cannot be shown to converge to the continuous case. In Phys. Rev. E 97, 012104 (2018), 10.1103/PhysRevE.97.012104, we have shown that the discrete q -entropy S˜q(n ) converges to the continuous case when the total number of states are properly taken into account in terms of a convergence factor. Ou and Abe [previous Comment, Phys. Rev. E 97, 066101 (2018), 10.1103/PhysRevE.97.066101] noted that this form of the discrete q -entropy does not conform to the Shannon-Khinchin expandability axiom. As a reply, we note that the fulfillment or not of the expandability property by the discrete q -entropy strongly depends on the origin of the convergence factor, presenting an example in which S˜q(n ) is expandable.

Approche en soins primaires pour les problèmes de consommation de cannabis

PubMed Central

Turner, Suzanne D.; Spithoff, Sheryl; Kahan, Meldon

2014-01-01

Résumé Objectif Étudier les caractéristiques et complications cliniques de la consommation à risque de cannabis et du trouble de consommation de cannabis, et présenter un protocole en cabinet pour le dépistage, l’identification et la prise en charge de ces problèmes. Sources des données Une recherche des essais contrôlés, des études d’observation et des révisions sur l’usage de cannabis par les adolescents et les jeunes adultes; les méfaits psychiatriques et médicaux liés au cannabis; le trouble de consommation de cannabis et son traitement; et les lignes directrices sur la consommation à faible risque de cannabis a été effectuée dans PubMed. Message principal Les médecins doivent questionner tous leurs patients quant à leur usage de cannabis. Ils doivent questionner plus souvent les adolescents et jeunes adultes de même que les personnes qui présentent un risque élevé de problèmes liés au cannabis (qui ont un trouble psychiatrique ou de consommation de drogue concomitant). Les problèmes pouvant être causés par le cannabis, comme les troubles de l’humeur, la psychose et les symptômes respiratoires, devraient susciter des questions sur la consommation de cannabis. Aux patients qui rapportent un usage de cannabis, les médecins devraient poser des questions sur la fréquence et la quantité consommée, la présence de symptômes de tolérance ou de sevrage, les tentatives de réduire leur consommation et la présence de problèmes liés au cannabis. Les usagers à faible risque fument, inhalent ou ingèrent le cannabis occasionnellement sans aucun signe de dysfonctionnement scolaire, professionnel ou social; les personnes dont l’usage est problématique consomment tous les jours ou presque tous les jours, ont de la difficulté à réduire leur consommation et leur fonctionnement scolaire, professionnel et social est perturbé. Les médecins devraient offrir à tous les patients dont l’usage est problématique des conseils et un bref counseling, en insistant sur les effets du cannabis sur la santé et en visant l’abstinence (certains groupes à risque élevé devraient s’abstenir complètement de consommer du cannabis) ou la réduction de la consommation, et ils doivent fournir des stratégies pratiques de réduction de la consommation. Les techniques d’entrevue motivationnelle doivent faire partie des séances de counseling. Les médecins devraient aiguiller les patients qui sont incapables de réduire leur consommation ou qui présentent des problèmes liés à leur usage de cannabis vers des soins spécialisés, tout en veillant à ce qu’ils demeurent en contact avec leur généraliste. De plus, les médecins devraient donner à tous les usagers de cannabis de l’information sur la consommation à faible risque. Conclusion Les médecins devraient effectuer au moins une fois chez tous leurs patients de leur pratique un test de dépistage de l’usage de cannabis, particulièrement chez les patients qui présentent des problèmes pouvant être causés par le cannabis. Les tests de dépistage doivent être plus fréquents chez les personnes à risque, soit au moins tous les ans. Il faut savoir distinguer la consommation à faible risque de l’usage problématique. Les patients dont l’usage est problématique doivent recevoir de brèves séances de counseling et ces patients doivent être aiguillés vers un spécialiste s’ils sont incapables de réduire leur consommation ou d’y mettre un terme.

Un exemple de volcanisme calco-alcalin de type orogénique mis en place en contexte de rifting (Cambrien de l'oued Rhebar, Meseta occidentale, Maroc)

NASA Astrophysics Data System (ADS)

El Hadi, Hassan; Tahiri, Abdelfatah; Simancas Cabrera, Fernando; González Lodeiro, Francisco; Azor Pérez, Antonio; Jesús Martínez Poyatos, David

2006-03-01

The Middle Cambrian calc-alkaline Oued Rhebar volcanic complex (western Meseta, Morocco) compares with rocks originated in orogenic contexts. The La/Nb ratios are relatively high (5.2), suggesting a lithospheric mantle origin. The La/Ta ratios, higher than 26, and the negative Nb anomaly indicate a lithospheric source contaminated by the continental crust. These rocks were generated in the Mesetian Mid-Cambrian rift and would have inherited their orogenic signature from the partial melting of a previously metasomatized mantle. To cite this article: H. El Hadi et al., C. R. Geoscience 338 (2006).

Generic Methodology for Verification and Validation (GM-VV) to Support Acceptance of Models, Simulations and Data (Methodologie generale de verification et de validation (GM-VV) visant a soutenir l acceptation des modeles, simulations et donnees)

DTIC Science & Technology

2015-01-01

RTO ou AGARD doivent comporter la dénomination « STO », « RTO » ou « AGARD » selon le cas, suivi du numéro de série. Des informations analogues...rapports de la STO au fur et à mesure de leur publication, vous pouvez consulter notre site Web (http://www.sto.nato.int/) et vous abonner à ce service...le cas, suivie du numéro de série (par exemple AGARD-AG-315). Des informations analogues, telles que le titre et la date de publication sont

The use of radiolabelling techniques to measure substantivity to, and penetration into, hair of protein hydrolysates.

PubMed

Jones, R T; Chahal, S P

1997-10-01

The use of 14C-labelled amino acids enables the measurement of both the total substantivity to hair and the degree of penetration into the hair shaft of amino acid mixtures derived from complete hydrolysis of proteins. The technique utilizes the fact that direct measurement of 14C radioactivity of the treated hair detects only the surface substantivity. Total substantivity can be determined following solubilization of the hair. Data obtained for wheat amino acids show significant penetration when used to treat hair from a shampoo or conditioner formulation. A similar technique has been investigated for a wheat protein partial hydrolysate using 14CNO for radiolabelling purposes and shows that significant penetration into hair can occur. L'utilisation d'amino-acides marques au 14C permet la mesure a la fois de l'absorption totale par les cheveux et du degre de penetration dans la fibre du cheveu de melanges d'amino-acides obtenus a partir d'une hydrolyse totale de proteines. La technique utilise le fait que la mesure directe de la radioactivite du 14C des cheveux traites ne detecte que l'absorption en surface. L'absorption totale peut etre determinee apres solubilisation des cheveux. Les donnees obtenues a partir d'amino-acides de ble montrent une penetration significative lors d'une utilisation pour traiter des cheveux a partir d'une formulation de shampoing ou d'apres-shampoing. Une technique similaire a ete exploree vis-a-vis d'un hydrolysat partiel d'une proteine de ble utilisant 14CNO a des fins de marquage, et montre qu'une penetration significative dans les cheveux peut avoir lieu.

QUELS FUTURS TRAITEMENTS POUR LA DEPENDANCE AU TABAC ET AU CANNABIS?

PubMed Central

LE FOLL, Bernard; JUSTINOVA, Zuzana; TANDA, Gianlugi; GOLDBERG, Steven R.

2009-01-01

RESUME Plus de trois millions de morts sont attribués au tabagisme dans le monde par an, et l’usage de tabac est en progression dans les pays en voie de développement. L’usage de tabac est donc une des rares causes de mortalité qui augmente, avec une prévision de plus de 10 millions de morts par an dans 30–40 ans. Le cannabis ou marijuana est la drogue illicite la plus consommée dans le monde et il n’y a actuellement pas de traitement disponible. Bien que les systèmes dopaminergiques jouent un rôle central dans les effets renforçants des drogues, d’autres systèmes sont impliqués. Nous présentons ici des résultats récents obtenus avec des antagonistes des récepteurs cannabinoides CB1, des récepteurs D3 de la dopamine et des récepteurs opioïdes. Ces antagonistes qui modulent de façon directe ou indirecte la transmission dopaminergique cérébrale représentent des approches prometteuses pour le traitement du tabagisme ou de la dépendance au cannabis. Ces approches sont à valider dans des essais cliniques. PMID:18663981

Contribution of Classic and Alternative Effector Pathways in Peanut-Induced Anaphylactic Responses

PubMed Central

Smit, Joost J.; Willemsen, Karina; Hassing, Ine; Fiechter, Danielle; Storm, Gert; van Bloois, Louis; Leusen, Jeanette H. W.; Pennings, Maarten; Zaiss, Dietmar; Pieters, Raymond H. H.

2011-01-01

Food allergy affects approximately 5% of children and is the leading cause of hospitalization for anaphylactic reactions in westernized countries. However, the pathways of anaphylaxis in food allergy are still relatively unknown. We investigated the effector pathways of allergic and anaphylactic responses of different strains of mice in a clinical relevant model of peanut allergy. C3H/HeOuJ, C57BL/6 and BALB/c mice were sensitized by intragastric peanut extract and challenged by intragastric or intraperitoneal injection of peanut. Peanut-specific T cell responses, IgE, IgG1 and IgG2a and mucosal mast cell degranulation were induced to different extent in C3H/HeOuJ, C57BL/6 and BALB/c mice. Interestingly, anaphylactic symptoms after systemic challenge were highest in C3H/HeOuJ followed by C57BL/6 but were absent in BALB/c mice. Mechanistic studies showed that the food allergic systemic anaphylaxis was dependent on platelets, FcRγ and mast cells, and partially dependent on platelet activating factor and monocytes/macrophages, depending on mouse strain. These data demonstrate that in three mouse strains, components of the classic and alternative anaphylactic cascade are differently expressed, leading to differential outcomes in parameters of allergic disease and food induced systemic anaphylaxis. PMID:22194949

Reduced cerebral ischemia-reperfusion injury in Toll-like receptor 4 deficient mice

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cao Canxiang; Yang Qingwu; Lv Fenglin

Inflammatory reaction plays an important role in cerebral ischemia-reperfusion injury, however, its mechanism is still unclear. Our study aims to explore the function of Toll-like receptor 4 (TLR4) in the process of cerebral ischemia-reperfusion. We made middle cerebral artery ischemia-reperfusion model in mice with line embolism method. Compared with C3H/OuJ mice, scores of cerebral water content, cerebral infarct size and neurologic impairment in C3H/Hej mice were obviously lower after 6 h ischemia and 24 h reperfusion. Light microscopic and electron microscopic results showed that cerebral ischemia-reperfusion injury in C3H/Hej mice was less serious than that in C3H/OuJ mice. TNF-{alpha} andmore » IL-6 contents in C3H/HeJ mice were obviously lower than that in C3H/OuJ mice with ELISA. The results showed that TLR4 participates in the process of cerebral ischemia-reperfusion injury probably through decrease of inflammatory cytokines. TLR4 may become a new target for prevention of cerebral ischemia-reperfusion injury. Our study suggests that TLR4 is one of the mechanisms of cerebral ischemia-reperfusion injury besides its important role in innate immunity.« less

Ustekinumab for Behçet's disease.

PubMed

Mirouse, Adrien; Barete, Stéphane; Monfort, Jean-Benoît; Resche-Rigon, Matthieu; Bouyer, Anne-Sophie; Comarmond, Cloé; Sène, Damien; Domont, Fanny; Ferfar, Yasmina; Cacoub, Patrice; Saadoun, David

2017-08-01

To evaluate the efficacy and safety of ustekinumab in the treatment of oral ulcers (OU) in patients with Behçet's disease (BD). Prospective study including 14 patients [median age of 39 (34; 41) years, with 71% of men] fulfilling criteria of the International Study Group for BD and with active OU resistant to colchicine. Patients received ustekinumab 90 mg (n = 11) or 45 mg (n = 3) subcutaneously at inclusion, at week 4, and every 12 weeks. The primary efficacy endpoint was the proportion of patients with complete response (CR), defined as no oral ulcer, at week 12. At week 12, 64% were in CR, 21% in partial response and 14% non-responders. The median number of OU decreased from 2 [2; 4] to 1 [0; 1.25] (p = 0.0005) at week 12. Mean change from baseline to week 12 of Behçet's syndrome activity score (BSAS) was 22.8 ± 0.3 (p = 0.01). The median daily corticosteroids dose decreased from 12.5 (10; 16.3) to 5 [5; 10] mg/day (p = 0.02). Three patients reported headaches, leading to discontinuation of ustekinumab in one case. After a median follow-up of 7 [3; 12] months, 10 (71%) patients were still receiving ustekinumab and four (28%) experienced a relapse. Decreased levels of circulating IL-17 and IL-12 [median [IQR]; 3.9 [1.6; 10.6] vs. 29.2 [25.2; 42.7] pg/ml, and 29.4 [23.1; 33.3] vs. 56.1 [51.1; 64.4] pg/ml, p = 0.008 for both] were observed under ustekinumab, respectively. Ustekinumab seems to be efficient and safe for patient with BD and refractory OU although relapses are frequent. Copyright © 2017 Elsevier Ltd. All rights reserved.

Odor, gaseous and PM10 emissions from small scale combustion of wood types indigenous to Central Europe

NASA Astrophysics Data System (ADS)

Kistler, Magdalena; Schmidl, Christoph; Padouvas, Emmanuel; Giebl, Heinrich; Lohninger, Johann; Ellinger, Reinhard; Bauer, Heidi; Puxbaum, Hans

2012-05-01

In this study, we investigated the emissions, including odor, from log wood stoves, burning wood types indigenous to mid-European countries such as Austria, Czech Republic, Hungary, Slovak Republic, Slovenia, Switzerland, as well as Baden-Württemberg and Bavaria (Germany) and South Tyrol (Italy). The investigations were performed with a modern, certified, 8 kW, manually fired log wood stove, and the results were compared to emissions from a modern 9 kW pellet stove. The examined wood types were deciduous species: black locust, black poplar, European hornbeam, European beech, pedunculate oak (also known as “common oak”), sessile oak, turkey oak and conifers: Austrian black pine, European larch, Norway spruce, Scots pine, silver fir, as well as hardwood briquettes. In addition, “garden biomass” such as pine cones, pine needles and dry leaves were burnt in the log wood stove. The pellet stove was fired with softwood pellets. The composite average emission rates for log wood and briquettes were 2030 mg MJ-1 for CO; 89 mg MJ-1 for NOx, 311 mg MJ-1 for CxHy, 67 mg MJ-1 for particulate matter PM10 and average odor concentration was at 2430 OU m-3. CO, CxHy and PM10 emissions from pellets combustion were lower by factors of 10, 13 and 3, while considering NOx - comparable to the log wood emissions. Odor from pellets combustion was not detectable. CxHy and PM10 emissions from garden biomass (needles and leaves) burning were 10 times higher than for log wood, while CO and NOx rise only slightly. Odor levels ranged from not detectable (pellets) to around 19,000 OU m-3 (dry leaves). The odor concentration correlated with CO, CxHy and PM10. For log wood combustion average odor ranged from 536 OU m-3 for hornbeam to 5217 OU m-3 for fir, indicating a considerable influence of the wood type on odor concentration.

In vitro antibacterial activity of adhesive systems on Streptococcus mutans.

PubMed

Paradella, Thaís Cachuté; Koga-Ito, Cristiane Yumi; Jorge, Antonio Olavo Cardoso

2009-04-01

To evaluate the antibacterial activity of three adhesive systems -- Prime & Bond 2.1 (PB), Clearfil SE Bond (CS) and One Up Bond F (OU) -- on Streptococcus mutans in vitro. Adherence and agar disk-diffusion tests were performed. For the adherence testing, 40 human enamel specimens (4 mm2) were sterilized and the adhesive sytems were applied (n = 10). The control group did not receive the application of any adhesive system. Specimens were immersed in brain heart infusion broth (BHI) inoculated with S. mutans standardized suspension (10(6) cells/ml) for 48 h at 37 degrees C and 5% CO2. The number of S. mutans cells adhered to each specimen was evaluated by the plating method on BHI agar. For agar disk-diffusion testing, adhesive disks and disks soaked in distilled water (negative control) or 0.2% chlorexidine (positive control) were incubated with S. mutans for 48 h. The diameters of the zones of bacterial inhibition were measured. Adherence data were transformed in logarithms of base 10 (log10). Data were submitted to Kruskal-Wallis and Student-Neuman-Keuls tests at the 5% level of significance. The results of the adherence test showed that One Up Bond F (OU) and Clearfil SE Bond (CS) did not differ significantly from one another, but allowed significantly less adherence than Prime & Bond 2.1 (PB) and control [mean log10 (standard deviation) values: PB 6.10 (0.19); CS primer 4.55 (0.98); OU 4.65 (0.54); control group 6.34 (0.27)]. The disk-diffusion test showed no significant difference between OU (diameter in mm: 3.02 +/- 0.13) and CS (3.0 +/- 0.12), but both were significantly more effective in inhibiting bacterial growth than PB (1.0 +/- 0.10). The self-etching systems Clearfil SE Bond and One Up Bond F presented a greater inhibitory effect against S. mutans, also in terms of adherence, than did the conventional system, Prime & Bond 2.1.

Traitement de la neuromyélite optique de Devic durant de la grossesse

PubMed Central

Daouda, Moussa Toudou; Obenda, Norlin Samuel; Assadeck, Hamid; Camara, Diankanagbe; Djibo, Fatimata Hassane

2016-01-01

La neuromyélite optique de Devic est une pathologie inflammatoire démyélinisante du système nerveux central qui affecte électivement la moelle spinale, le nerf optique et les régions cérébrales à haute expression d’antigènes aquaporine 4. Il s’agit d’une pathologie auto-immune sévère due à des auto-anticorps dirigés contre l’aquaporine 4, à taux de morbidité et de mortalité élevé. Contrairement à d’autres pathologies inflammatoires notamment la sclérose en plaques ou polyarthrite rhumatoïde, la grossesse n’exerce aucune influence sur l’activité de la neuromyélite optique d’où la nécessité d’instaurer un traitement de fond durant toute la grossesse. La corticothérapie représente le traitement de premier choix de la neuromyélite optique durant la grossesse. D’autres traitements peuvent également être utilisés notamment le rituximab, certains immunosuppresseurs, les immunoglobulines. Le traitement par immunosuppresseurs ou rituximab est proposé lorsque la corticothérapie au long cours est contre-indiquée ou en cas d’inefficacité à celle-ci ou encore lorsque les effets secondaires sont intolérables. Les immunoglobulines sont administrées en cas de poussées sévères de la neuromyélite optique qui ne répondent pas aux bolus de methylprednisolone. Les immunoglobulines peuvent également être poursuivies seules à la dose 0,4g/kg/j toutes les 6 à 8 semaines jusqu’à l’accouchement. La plasmaphérèse est également une bonne alternative aux bolus de methylprednisolone lorsque les poussées sont très sévères. PMID:27800085

Espectroscopia de candidatos a remanescentes de aglomerados abertos

NASA Astrophysics Data System (ADS)

Pavani, D. B.; Bica, E.; Ahumada, A. V.; Clariá, J. J.

2003-08-01

A pesquisa sobre remanescentes de aglomerados abertos tem despertado grande interesse. Seguindo esta tendência encontramos estudos teóricos e observacionais. Os primeiros baseiam-se em simulações numéricas buscando determinar fração de binárias e distâncias galatocêntricas, tempo de vida e conteúdo estelar. Estes estão relacionados à função inicial de massa e densidade de estrelas, ou seja, se ricos ou pobremente povoados, compactos ou esparsos. No caso observacional procuram-se identificar os remanescentes considerando-se que trazem estas assinaturas de seus percursores. No presente estudo empregamos espectroscopia para analisar oito concentrações pobremente povoadas, previamente classificadas como aglomerados abertos, sendo sete compactas e uma esparsa. As observações foram obtidas através do telescópio de 2,15 m do CASLEO em San Juan, Argentina, em turnos entre 2001 e 2003. Utilizamos uma câmara CCD contendo um chip Tektronics de 1024X1024 pixeis aliado a um espectrógrafo REOSC. O domínio espectral vai de 3700 a 7000 Å. As reduções foram realizadas no Observatório Astronômico de Córdoba (Argentina) usando pacotes IRAF padrões. Determinamos idades, avermelhamentos e tipos espectrais através de comparações com biblioteca de estrelas e de aglomerados. Em alguns casos nossos espectros estavam dominados por estrelas individuais às quais determinamos seus tipos espectrais. Aos oito objetos adicionamos mais cinco da literatura recente analisados via espectro ou diagrama cor-magnitude. O histograma resultante contém idades típicas entre 0.5 e 3 Ganos. Considerando que predominantemente estes objetos encontram-se na vizinhança solar e, portanto, não cruzaram muitas vezes o plano Galático esperamos que a diferença no tempo necessário para dissolução destes prováveis remanescentes seja em função de diferentes massas iniciais.

Hong-Ou-Mandel Gravitational Wave Space spectrometER - HOMER mission

NASA Astrophysics Data System (ADS)

Jacinto de Matos, Clovis; Tajmar, Martin

2018-06-01

Michelson type gravitational wave detectors measure the strain caused by gravitational waves on the interferometer's arms. Gravitational waves can also cause the rotation of photon's linear polarization vector, thus disturbing the interference of entangled photons in Hong-Ou-Mandel (HOM) interferometers. Here one uses that physical phenomenon to devise a spectrometer for gravitational waves through the implementation of a Hong-Ou-Mandel interferometer in Earth geostationary orbit with a constellation of three different spacecraft in accurate formation flight. We call this mission, the Hong-Ou-Mandel Gravitational Waves Space SpectrometER (HOMER). HOMER will cover the part of the gravitational wave spectrum with wavelengths around λ =105 km, which falls between the long wavelength detection range of LISA, around λ =106 km, and of ground based detectors like LIGO, around λ =103 km. With respect to Michelson type detectors, the proposed concept for the detection and spectral analysis of gravitational waves has the advantage of operating without the need of drag free satellites, however it requires a relative precision of the attitude between satellites of the order of the gravitational waves amplitude δθ / θ ∼ h ∼10-20 , which makes the architecture of the HOMER mission as challenging as the Michelson type space detectors. The difficulty being however transferred from the monitoring of the relative distance between spacecraft (for Michelson antennas) to their relative attitude. By focusing on photons polarization instead of photons phase one can measure the spectrum of the detected gravitational signal. As a bonus, the proposed instrument could also investigate the influence of spacetime curvature on photons quantum entanglement, thus experimentally peering into the relation between general relativity and quantum mechanics, which is currently a subject of high interest in theoretical physics. This paper will describe the HOMER mission concept in general and the main elements of the payload and spacecraft design in particular.

Geochemical, isotopic, and dissolved gas characteristics of groundwater in a fractured crystalline-rock aquifer, Savage Municipal Well Superfund site, Milford, New Hampshire, 2011

USGS Publications Warehouse

Harte, Philip T.

2013-01-01

Tetrachloroethylene (PCE), a volatile organic compound, was detected in groundwater from deep (more than (>) 300 feet (ft) below land surface) fractures in monitoring wells tapping a crystalline-rock aquifer beneath operable unit 1 (OU1) of the Savage Municipal Well Superfund site (Weston, Inc., 2010). Operable units define remedial areas of contaminant concern. PCE contamination within the fractured-rock aquifer has been designated as a separate operable unit, operable unit 3 (OU3; Weston, Inc., 2010). PCE contamination was previously detected in the overlying glacial sand and gravel deposits and basal till, hereafter termed the Milford-Souhegan glacial-drift (MSGD) aquifer (Harte, 2004, 2006). Operable units 1 and 2 encompass areas within the MSGD aquifer, whereas the extent of the underlying OU3 has yet to be defined. The primary original source of contamination has been identified as a former manufacturing facility—the OK Tool manufacturing facility; hence OU1 sometimes has been referred to as the OK Tool Source Area (New Hampshire Department of Environmental Services, undated). A residential neighborhood of 30 to 40 houses is located in close proximity (one-quarter of a mile) from the PCE-contaminated monitoring wells. Each house has its own water-supply well installed in similar rocks as those of the monitoring wells, as indicated by the New Hampshire State geologic map (Lyons and others, 1997). An investigation was initiated in 2010 by the U.S. Environmental Protection Agency (USEPA) region 1, and the New Hampshire Department of Environmental Services (NHDES) to assess the potential for PCE transport from known contaminant locations (monitoring wells) to the residential wells. The U.S. Geological Survey (USGS) and the NHDES entered into a cooperative agreement in 2011 to assist in the evaluation of PCE transport in the fractured-rock aquifer. Periodic sampling over the last decade by the USEPA and NHDES has yet to detect PCE in groundwater from the residential-supply wells (as of 2012). However, part of assessing the potential for PCE transport involves understanding the origin of the groundwater in the monitoring and residential wells. One of the tools in delineating the movement of groundwater to wells, particularly in complex, highly heterogeneous fractured-rock aquifers, is the understanding of the geochemical and isotopic composition of groundwater (Lipfert and Reeve, 2004; Harte and others, 2012). This report summarizes findings from analyses of geochemical, isotopic, and dissolved gas characteristics of groundwater. Samples of groundwater were collected in 2011 from monitoring wells and nearby residential-supply wells in proximity to OU1.

Sepsis in a university hospital: a prospective study for the cost analysis of patients' hospitalization.

PubMed

Barreto, Maynara Fernanda Carvalho; Dellaroza, Mara Solange Gomes; Kerbauy, Gilselena; Grion, Cintia Magalhães Carvalho

2016-04-01

To estimate the cost of hospitalization of patients with severe sepsis or septic shock admitted or diagnosed in the Urgent and Emergency sector at a university hospital and followed until the clinical outcome. An epidemiological, prospective, observational study conducted in a public hospital in southern Brazil for the period of one year (August 2013 to August 2014). Sepsis notification forms, medical records and data of the cost sector were used for the collection of clinical and epidemiological data. The sample comprised 95 patients, resulting in a total high cost of hospitalization (R$ 3,692,421.00), and an average of R$ 38,867.60 per patient. Over half of the total value of the treatment of sepsis (R$ 2,215,773.50) was assigned to patients who progressed to death (59.0%). The higher costs were related to discharge, diagnosis of severe sepsis, the pulmonary focus of infection and the age group of up to 59 years. The high cost of the treatment of sepsis justifies investments in training actions and institution of protocols that can direct preventive actions, and optimize diagnosis and treatment in infected and septic patients. Estimar o custo da internação de pacientes com sepse grave ou choque séptico admitidos ou diagnosticados no setor de Urgências e Emergências de um hospital universitário e seguidos até o desfecho clínico. Estudo epidemiológico, prospectivo e observacional, realizado em um hospital público do sul do Brasil, no período de 1 ano (agosto de 2013 a agosto de 2014). A coleta dos dados clínico-epidemiológicos utilizou fichas de notificação de sepse, prontuários e dados do setor de custos. Foi realizada análise de tendência central, dispersão e quartis dos custos das internações. Amostra composta por 95 pacientes que totalizaram elevado custo da internação (R$ 3.692.421,00), com média de R$ 38.867,60 por paciente. Mais da metade do valor total do tratamento da sepse (R$ 2.215.773,50) destinou-se a pacientes que evoluíram a óbito (59,0%). Os maiores custos foram relacionados à alta, ao diagnóstico de sepse grave, ao foco infeccioso pulmonar e à faixa etária até os 59 anos. O elevado custo com o tratamento da sepse justificam investimentos em ações de capacitação e instituição de protocolos que possam direcionar ações preventivas, otimizar o diagnóstico e a terapêutica em pacientes infectados e séptico.

Association between Obstructive Sleep Apnea and Myocardial Infarction: A Systematic Review.

PubMed

Porto, Fernanda; Sakamoto, Yuri Saho; Salles, Cristina

2017-04-01

Obstructive sleep apnea (OSA) has been associated to cardiovascular risk factors. However, the association between OSA and cardiovascular disease is still controversial. The objective of the present study was to verify the association between OSA and myocardial infarction (MI). This is a systematic review of the literature performed through electronic data sources MEDLINE/PubMed, PubMed Central, Web of Science and BVS -Biblioteca Virtual em Saúde (Virtual Health Library). The descriptors used were: 'obstructive sleep apnea' AND 'polysomnography' AND 'myocardial infarction' AND 'adults NOT 'treatment.' The present work analysed three prospective studies, selected from 142 articles. The studies followed a total sample of 5,067 OSA patients, mostly composed by male participants. All patients underwent night polysomnography, and all studies found an association between OSA and fatal and non-fatal cardiovascular outcomes. Thus, we were able to observe that 644 (12.7%) of the 5,067 patients suffered MI or stroke, or required a revascularization procedure, and 25.6% of these cardiovascular events were fatal. MI was responsible for 29.5% of all 644 analysed outcomes. There is an association between OSA and MI, in male patients, and apnea and hypopnea index (AHI) are the most reliable markers. Resumo A apneia obstrutiva do sono (AOS) tem sido associada a fatores de risco cardiovascular, porém a relação entre a AOS e doença cardiovascular ainda é controversa. O objetivo do presente estudo foi verificar a associação entre AOS e infarto do miocárdio (IM). Revisão sistemática de literatura por meio das fontes de dados eletrônicas MEDLINE/PubMed, PubMed Central, Web of Science e Biblioteca Virtual em Saúde (BVS). Os descritores utilizados foram: "obstructive sleep apnea" AND "polysomnography" AND "myocardial infarction" AND "adults" NOT "treatment".O presente trabalho analisou três estudos prospectivos, selecionados dentre 142 artigos encontrados. Os estudos acompanharam uma amostra total de 5.067 pacientes diagnosticados com AOS, composta majoritariamente por participantes do sexo masculino. Todos os pacientes realizaram polissonografia noturna, e todas as pesquisas encontraram associação entre AOS e desfechos cardiovasculares fatais e não fatais. Assim, foi possível observar que 644 (12,7%) dos 5.067 pacientes sofreram IM ou acidente vascular cerebral, ou precisaram de procedimento de revascularização, sendo que 25,6% desses eventos cardiovasculares foram fatais. O IM foi responsável por 29,5% do total de 644 desfechos analisados. Existe associação entre AOS e IM, no sexo masculino, sendo o índice de apneia e hipopneia (IAH) um dos marcadores mais fidedignos.

Frequency-domain Hong-Ou-Mandel interference with linear optics.

PubMed

Imany, Poolad; Odele, Ogaga D; Alshaykh, Mohammed S; Lu, Hsuan-Hao; Leaird, Daniel E; Weiner, Andrew M

2018-06-15

The Hong-Ou-Mandel (HOM) interference is one of the most fundamental quantum-mechanical effects that reveal a nonclassical behavior of single photons. Two identical photons that are incident on the input ports of an unbiased beam splitter always exit the beam splitter together from the same output port, an effect referred to as photon bunching. In this Letter, we utilize a single electro-optic phase modulator as a probabilistic frequency beam splitter, which we exploit to observe HOM interference between two photons that are in different spectral modes, yet are identical in other characteristics. Our approach enables linear optical quantum information processing protocols using the frequency degree of freedom in photons such as quantum computing techniques with linear optics.

Development of an Assessment Methodology for Demonstrating Usability, Technical Maturity, and Operational Benefits of Advanced Medical Technology (Developpement d’une Methodologie d’Evaluation Permettant de Demontrer la Facilite d’Utilisation, la Maturite Technique et les Avantages Operationnels des Technologies Medicales Evoluees)

DTIC Science & Technology

2010-09-01

de nations, que ce soit au sein de l’Alliance ou dans le cadre du Partenariat pour la paix, ont développé au cours des ...pour l’évacuation des blessés (CASEVAC). Certaines de ces technologies peuvent inclure en temps réel le contrôle de l’état du combattant/patient, la ...localisation du patient, le contrôle de l’état de la logistique médicale, ou encore l’établissement de rapports épidémiologiques. Le

The New Absolute Parameters of OU Gem - The Star of BY Dra Type

NASA Astrophysics Data System (ADS)

Mishenina, T. V.; Glazunova, L. V.; Soubiran, C.; Kovtyukh, V. V.

2010-12-01

The spectra of OU Gem were obtained with the fiber-fed echelle spectrograph SOPHIE at the 1.93-m telescope of the Observatoire de Haute- Provence (France). The temperatures of components of the system were defined and are equal to 5013 ± 15 K and 4486±50 K for primary (A) and secondary (B) components, accordingly. The rotation velocity of components are measured: for primary component it is equal to 5.1±1 km/s and 6.2 ± km/s for the secondary one. The definition of radial velocities of components by LSD profile method and redetermination of spectral orbital elements were carried out. New absolute parameters of components were obtained too.

Computer Grade-Keeping Programs: User’s Guide.

DTIC Science & Technology

1981-12-01

ady 1] L- CLists the file in reverse order) 35U 340 64L5Lu) ZULU TRIBE 32 ESE 3.)u 642400 YANKEE REBEL 3j EOE 3LU 84230U XhAY VISIWiN 01 ENA luu o401U...VI61ON 00.O00O 00.0000 00.0000 00,0000 24 YANKEE REBEL 00.0000 00 0000 00 0000 00.0000 25 ZULU TRIBE Ou.0000 00.0000 00.0000 00.0000 8 GRADE SUBMISSION...90. 90,70o.’ o.U 0 o, o 90, 0,90,90 ,80,80 60,70,70,8080 70,-- 70 ALPHA ROBERT B 90.00 bRAVO MICHAEL D 90.00 ZULU TRIBE 70.00 AhE THESE GRADES

Direct observation of phase-sensitive Hong-Ou-Mandel interference

NASA Astrophysics Data System (ADS)

Marek, Petr; Zapletal, Petr; Filip, Radim; Hashimoto, Yosuke; Toyama, Takeshi; Yoshikawa, Jun-ichi; Makino, Kenzo; Furusawa, Akira

2017-09-01

The quality of individual photons and their ability to interfere are traditionally tested by measuring the Hong-Ou-Mandel photon bunching effect. However, this phase-insensitive measurement only tests the particle aspect of the quantum interference, leaving out the phase-sensitive aspects relevant for continuous-variable processing. To overcome these limitations we formulate a witness capable of recognizing both the indistinguishability of the single photons and their quality with regard to their continuous-variable utilization. We exploit the conditional nonclassical squeezing and show that it can reveal both the particle and the wave aspects of the quantum interference in a single set of direct measurements. We experimentally test the witness by applying it to a pair of independent single photons retrieved on demand.

Universal ideal behavior and macroscopic work relation of linear irreversible stochastic thermodynamics

NASA Astrophysics Data System (ADS)

Ma, Yi-An; Qian, Hong

2015-06-01

We revisit the Ornstein-Uhlenbeck (OU) process as the fundamental mathematical description of linear irreversible phenomena, with fluctuations, near an equilibrium. By identifying the underlying circulating dynamics in a stationary process as the natural generalization of classical conservative mechanics, a bridge between a family of OU processes with equilibrium fluctuations and thermodynamics is established through the celebrated Helmholtz theorem. The Helmholtz theorem provides an emergent macroscopic ‘equation of state’ of the entire system, which exhibits a universal ideal thermodynamic behavior. Fluctuating macroscopic quantities are studied from the stochastic thermodynamic point of view and a non-equilibrium work relation is obtained in the macroscopic picture, which may facilitate experimental study and application of the equalities due to Jarzynski, Crooks, and Hatano and Sasa.

Hong-Ou-Mandel interference of entangled Hermite-Gauss modes

NASA Astrophysics Data System (ADS)

Zhang, Yingwen; Prabhakar, Shashi; Rosales-Guzmán, Carmelo; Roux, Filippus S.; Karimi, Ebrahim; Forbes, Andrew

2016-09-01

Hong-Ou-Mandel (HOM) interference is demonstrated experimentally for entangled photon pairs in the Hermite-Gauss (HG) basis. We use two Dove prisms in one of the paths of the photons to manipulate the entangled quantum state that enters the HOM interferometer. It is demonstrated that, when entangled photon pairs are in a symmetric Bell state in the Laguerre-Gauss (LG) basis, they will remain symmetric after decomposing them into the HG basis, thereby resulting in no coincidence events after the HOM interference. On the other hand, if the photon pairs are in an antisymmetric Bell state in the LG basis, then they will also be antisymmetric in the HG basis, thereby producing only coincidence events as a result of the HOM interference.

Some physical approaches to protein folding

NASA Astrophysics Data System (ADS)

Bascle, J.; Garel, T.; Orland, H.

1993-02-01

To understand how a protein folds is a problem which has important biological implications. In this article, we would like to present a physics-oriented point of view, which is twofold. First of all, we introduce simple statistical mechanics models which display, in the thermodynamic limit, folding and related transitions. These models can be divided into (i) crude spin glass-like models (with their Mattis analogs), where one may look for possible correlations between the chain self-interactions and the folded structure, (ii) glass-like models, where one emphasizes the geometrical competition between one- or two-dimensional local order (mimicking α helix or β sheet structures), and the requirement of global compactness. Both models are too simple to predict the spatial organization of a realistic protein, but are useful for the physicist and should have some feedback in other glassy systems (glasses, collapsed polymers .... ). These remarks lead us to the second physical approach, namely a new Monte-Carlo method, where one grows the protein atom-by-atom (or residue-by-residue), using a standard form (CHARMM .... ) for the total energy. A detailed comparison with other Monte-Carlo schemes, or Molecular Dynamics calculations, is then possible; we will sketch such a comparison for poly-alanines. Our twofold approach illustrates some of the difficulties one encounters in the protein folding problem, in particular those associated with the existence of a large number of metastable states. Le repliement des protéines est un problème qui a de nombreuses implications biologiques. Dans cet article, nous présentons, de deux façons différentes, un point de vue de physicien. Nous introduisons tout d'abord des modèles simples de mécanique statistique qui exhibent, à la limite thermodynamique, des transitions de repliement. Ces modèles peuvent être divisés en (i) verres de spin (éventuellement à la Mattis), où l'on peut chercher des corrélations entre les interactions intrachaîne et la structure repliée, (ii) verres, où l'on met l'accent sur la compétition géométrique entre l'ordre local uni- ou bi-dimensionnel (qui modèle les structures en hélices α ou en feuillets β), et la contrainte globale de compacité. Ces deux types de modèles sont trop simples pour l'étude de vraies protéines, mais ils devraient s'appliquer dans le domaine de la transition vitreuse, des polymères collapsés,... La deuxième voie d'étude est une méthode Monte-Carlo, où on fait croître la protéine atome par atome (ou résidu par résidu), à l'aide d'une forme donnée de l'énergie totale de la protéine (CHARMM, ... ). Cette méthode peut être alors comparée aux autres méthodes numériques; nous comparons ainsi nos résultats avec des calculs de dynamique moléculaire pour le cas des poly-alanines. Cette double approche est une bonne illustration des difficultés que l'on rencontre dans le problème du repliement des protéines (nombreux états métastables, ... ).

Effets tardifs d'une irradiation corporelle totale sur le métabolisme intraneuronal de la dopamine et de la sérotonine

NASA Astrophysics Data System (ADS)

Joubert, C.; Jacquet, N.; Lambert, F.; Martin, S.; Martin, C.

1998-04-01

Whole-body irradiation leads to delayed cognitive dysfunction which could result from perturbations of neurotransmission, specially the dopaminergic and the serotoninergic one. The aim of this study was to determine the concentrations of dopamine (DA), serotonin (5-HT) and their metabolites in three cerebral areas of rats, one month after (neutron-gamma) irradiation at 3.38Gy. An increase of DA, 5-HT, and their catabolites was observed. These effects are weak but observed in older rats. Au cours des mois suivant une irradiation corporell totale peuvent se manifester des troubles comportementaux qui pourraient être la conséquence d'altérations de la neuraotransmission, plus particulièrement de la transmission dopaminergique ou sérotoninergique. Nous avons recherché les variations des taux de dopamine (DA), de sérotonine (5-HT) et de leurs métabolites dans 3structures cérébrales 1 mois après une irradiation (neutron-gamma) à la dose de 3,38Gy. Les résultats préliminaires mettent en évidence une augmentation des taux de DA, de 5-HT et de leurs catabolites ; ces effets sont plus discrets mais similaires à ceux observés chez des animaux plus âgés.

Characterization and geostatistical mapping of water salinity: A case study of terminal complex in the Oued Righ Valley (southern Algeria)

NASA Astrophysics Data System (ADS)

Belkesier, Mohamed Saleh; Zeddouri, Aziez; Halassa, Younes; Kechiched, Rabah

2018-05-01

The region of Oued Righ contains large quantities of groundwater hosted by the three aquifers: the Terminal Complex (CT), the Continental Intercalary (CI) and the phreatic aquifer. The present study is focused on the water from CT aquifer in order to characterize their salinity using geostatistical tool for maping. Indeed, water in this aquifer show a high mineralization exceeding the OMS standards. The main hydro-chemical facies of this water is Chloride-Sodium and Sulfate-Sodium. The elementary statistics have been performed on the physico-chemical analysis from 97 wells whereas 766 wells were analyzed on salinity and are used for the geostatistical mapping. The obtained results show a spatial evolution of the salinity toward the direction South to the North. The salinity is locally strong in the central part of Oued Righ valley. The non-parametric geostatistic of indicator kriging was performed on the salinity data using a cut-off of 5230 mg/l which represents the average value in the studied area. The indicator Kriging allows the estimation of salinity probabilities I (5230 mg / l) in the water of the CT aquifer using bloc model (500 x 500 m). The automatic mapping is used to visualize the distribution of the kriged probabilities of salinity. These results can help to ensure a rational and a selective exploitation of groundwater according the salinity contents.

Anomalous diffusion due to hindering by mobile obstacles undergoing Brownian motion or Orstein-Ulhenbeck processes.

PubMed

Berry, Hugues; Chaté, Hugues

2014-02-01

In vivo measurements of the passive movements of biomolecules or vesicles in cells consistently report "anomalous diffusion," where mean-squared displacements scale as a power law of time with exponent α<1 (subdiffusion). While the detailed mechanisms causing such behaviors are not always elucidated, movement hindrance by obstacles is often invoked. However, our understanding of how hindered diffusion leads to subdiffusion is based on diffusion amidst randomly located immobile obstacles. Here, we have used Monte Carlo simulations to investigate transient subdiffusion due to mobile obstacles with various modes of mobility. Our simulations confirm that the anomalous regimes rapidly disappear when the obstacles move by Brownian motion. By contrast, mobile obstacles with more confined displacements, e.g., Orstein-Ulhenbeck motion, are shown to preserve subdiffusive regimes. The mean-squared displacement of tracked protein displays convincing power laws with anomalous exponent α that varies with the density of Orstein-Ulhenbeck (OU) obstacles or the relaxation time scale of the OU process. In particular, some of the values we observed are significantly below the universal value predicted for immobile obstacles in two dimensions. Therefore, our results show that subdiffusion due to mobile obstacles with OU type of motion may account for the large variation range exhibited by experimental measurements in living cells and may explain that some experimental estimates are below the universal value predicted for immobile obstacles.

Les agressions sexuelles des jeunes ayant une incapacité ou une maladie chronique

PubMed Central

Kaufman, M

2011-01-01

Pour diverses raisons, les enfants et les adolescents ayant une incapacité ou une maladie chronique sont plus vulnérables aux agressions sexuelles. Les dispensateurs de soins, de même que les parents et les éducateurs, doivent se méfier davantage de la possibilité d’agression sexuelle au sein de cette population. Les médecins, tout particulièrement, doivent prôner des politiques pour prévenir ou déceler les agressions dans les hôpitaux, les écoles et autres établissements. Ces politiques incluent le dépistage détaillé et la surveillance étroite des employés et des bénévoles, la présence d’un chaperon aux examens physiques et aux interventions thérapeutiques, la supervision des sorties et une culture qui favorise la vie privée du patient en établissement. De plus, les médecins doivent favoriser la conscience de soi et l’habilitation des patients et leur donner très tôt des conseils préventifs au sujet de la sexualité, de l’habilitation personnelle et des risques d’agression. Le présent document de principes remplace celui que la Société canadienne de pédiatrie a publié en 1997.

Quand le malheur frappe les bénéficiaires de la sécurité du revenu. Sur qui peuvent-ils s’appuyer ?

PubMed Central

Tousignant, Michel; Caron, Jean

2013-01-01

Cette étude analyse les conditions de réalisation du soutien social dans les quartiers de Saint-Henri et de la Pointe Saint-Charles, en comparant un groupe de 61 prestataires de la sécurité du revenu avec un échantillon de 21 personnes de la population vivant au-dessus du seuil de la pauvreté, et en fonction du degré de détresse dans chaque groupe. Elle vise également à décrire comment une adversité vécue par les prestataires avec ou sans détresse vient briser ou modifier le réseau de soutien. Les résultats indiquent que le réseau social est moins fiable en présence de détresse qu’en son absence, que les personnes en détresse se sont vues plus fréquemment refuser du soutien ou être abandonnées et qu’elles ont davantage de personnes nuisibles dans leur entourage. De plus, les événements vécus comportent souvent une atteinte à leur réputation, des menaces, des trahisons et des refus à un droit légitime. Les personnes en détresse sont aussi davantage isolées. PMID:16505926

Synthese, etude structurale et electrochimique des materiaux d'electrode positive d'oxydes mixtes lithium cobalt nickel oxide (0 /= 1) pour les batteries rechargeables au lithium

NASA Astrophysics Data System (ADS)

Grincourt, Yves

Depuis une dizaine d'annees, on observe un interet grandissant pour les batteries rechargeables au lithium de tension superieure a 4 volts. La commercialisation de ces batteries pour l'electronique grand marche tend de plus en plus a supplanter celle des accumulateurs Ni-Cd et Ni-MH, de tension nominate 1,2 V. Ces batteries au lithium font appel a des materiaux d'electrode positive (cathode a la decharge) du type oxydes mixtes de metaux de transition LiMnO 2, LiMn2O4, LiNiO2 ou LiCoO2. Si le compose LiCoO2 est relativement aise a synthetiser, il n'en demeure pas moins que le cobalt reste un metal plus couteux compare au nickel et au manganese. La synthese de LiNiO2, quart a elle, demeure un probleme du point de vue stoechiometrique. Un defaut de lithium (5 a 10% molaire) conduira a des proprietes electrochimiques mediocres de la batterie. Dans cette etude nous nous proposons donc de preparer par voie humide et par voie seche les materiaux d'electrode positive de la famille LiCoyNi1-yO2 aver (0 ≤ y ≤ 1) et d'etudier en detail l'influence du pourcentage de nickel et de cobalt sur les proprietes electrochimiques des oxydes mixtes Li-Ni-Co. Une des caracteristiques est la morphologie plus fine des poudres de materiaux, observes par microscopie electronique a balayage (MEB). Un traitement thermique a plus basse temperature (750°C) que pour LiCoO2 (850°C) ainsi qu'un leger exces de lithium dans la preparation, ont permis d'aboutir a un materiau de stoechiometrie quasi parfaite. Neanmoins, le role de pilfer joue par 2 a 4% de moles de Ni2+ presents sur les sites lithium, permet de conserver intacte la structure hexagonale de la maille entre deux cycles consecutifs. Afin de mieux comprendre l'influence du vieillissement dune demi-pile Li/LiMeO2 (Me = Ni, Co) a temperature ambiante, des etudes electrochimiques et d'impedance spectroscopique ont ete menees en parallele. Le vieillissement de la cellule s'accompagne seulement dune chute de son potentiel due a son auto-decharge. Neanmoins, il est encore possible de la relancer en cyclage par la suite. Une baisse de la valeur de la resistance totale interfaciale et des frequences au sonnet semble indiquer une modification chimique et/ou structurale des films de passivations, pent-etre due a une transformation de ces films lors du cyclage ou a leur degradation. (Abstract shortened by UMI.)

La prise en charge des troubles de santé mentale par les omnipraticiens du Québec

PubMed Central

Fleury, Marie-Josée; Farand, Lambert; Aubé, Denise; Imboua, Armelle

2012-01-01

Résumé Objectif Cette recherche vise à documenter la prise en charge des troubles mentaux (TM) par les omnipraticiens. Type d’étude Il s’agit d’une étude mixte intégrant un questionnaire auto-administré et des entrevues qualitatives. La banque de données administratives des actes médicaux de la Régie de l’assurance maladie du Québec a aussi été analysée. Contexte La province de Québec. Participants Un total de 1415 omnipraticiens de différents lieux de pratiques ont été sollicités pour le questionnaire; 970 ont été rejoints. Un sous-groupe de 60 omnipraticiens a été rejoint pour les entrevues. Principaux paramètres à l'étude La prévalence annuelle des consultations reliées à des TM courants (TMC) ou graves (TMG), les pratiques cliniques, les pratiques de collaboration, les facteurs facilitant ou entravant la prise en charge des TM, ainsi que les recommandations pour l’amélioration du système de soins. Résultats Le taux de réponse a été de 41% (n = 398 omnipraticiens) pour le questionnaire et de 63% (n = 60) pour les entrevues. Environ 25 % des visites chez les omnipraticiens sont associées à des TM. Presque tous les omnipraticiens prennent en charge des TMC et se sentent compétents pour le faire, à l’inverse de la situation retrouvée pour les TMG. Près de 20 % des TMC sont référés (principalement à des intervenants psychosociaux), alors que près de 75 % des TMG sont référés (surtout en psychiatrie et à l’urgence). Plus de 50 % des omnipraticiens affirment n’entretenir aucun contact avec l’une ou l’autre des ressources de santé mentale. Plusieurs facteurs influencent la prise en charge des TM: les profils des patients (complexité des TM, troubles concomitants); les caractéristiques des omnipraticiens (réseau informel, formation); la culture professionnelle (travail en silo, mécanismes cliniques formalisés); le milieu institutionnel (multidisciplinarité, salariat); l’organisation des services (ressources; coordination formalisée) et l’environnement (politiques). Conclusion Le rôle clé des omnipraticiens et leur soutien à la prise en charge des TM ont été démontrés, spécifiquement pour les TMC. Pour une prise en charge optimale des soins primaires de santé mentale, des stratégies à composantes multiples, dont les soins partagés, devraient être davantage déployées.

Geology and hydrocarbon potential of the Oued Mya Basin, Algeria

DOE Office of Scientific and Technical Information (OSTI.GOV)

Benamrane, O.; Messaoudi, M.; Messelles, H.

1992-01-01

The hydrocarbon System Ourd Mya is located in the Sahara Basin. It is one of the producing basin in Algeria. The stratigraphic section consists of Paleozoic and Mesosoic, it is about 5000m thick. In the eastern part, the basin is limited by the Hassi-Messaoud high zone which is a giant oil field producing from the Cambrian sands. The western part is limited by Hassi R'mel which is one of the biggest gas field in the world, it is producing from the triassic sands. The Mesozoic section is laying on the lower Devonian and in the eastern part, on the Cambrian.more » The main source rock is the Silurian shale with an average thickness of 50m and a total organic matter of 6% (14% in some cases). Results of maturation modeling indicate that the lower Silurian source is in the oil window. The Ordovician shales are also a source rock, but in a second order. Clastic reservoirs are in the Triassic sequence which is mainly fluvial deposits with complex alluvial channels, it is the main target in the basin. Clastic reservoirs within the lower Devonian section have a good hydrocarbon potential in the east of the basin through a southwest-northeast orientation. The late Triassic-Early Jurassic evaporites overlie the Triassic clastic interval and extend over the entire Oued Mya Basin. This is considered as a super-seal evaporate package, which consists predominantly of anhydrite and halite. For Paleozoic targets, a large number of potential seals exist within the stratigraphic column. The authors infer that a large amount of the oil volume generated by the Silurian source rock from the beginning of Cretaceous until now, still not discovered could be trapped within structure closures and mixed or stratigraphic traps related to the fluvial Triassic sandstones, marine Devonian sands and Cambro-Ordovician reservoirs.« less

Nécrolyse épidermique liée à l'application cutanée d'une solution d'hydroxyde de potassium

PubMed Central

Korsaga-Somé, Nina; Tapsoba, Patrice; Ouédraogo, Muriel Sidnoma; Ilboudo, Léopold Baowendsom; Barro-Traoré, Fatou; Niamba, Pascal; Traoré, Adama

2015-01-01

Dans nos régions, une solution d'hydroxyde de potassium est régulièrement utilisée en application sur la peau comme traitement traditionnel dans le but de traiter un prurit ou une éruption cutanée. Dans notre pratique quotidienne, nous observons de plus en plus de réactions cutanées à ce type de traitement. Nous rapportons un cas de nécrolyse épidermique généralisée suite à l'application d'une solution concentrée d'hydroxyde de potassium. Il s'agissait d'une patiente de 51 ans, séropositive au VIH2, et au virus de l'hépatite virale C, mais non éligible au traitement antirétroviral. Elle était hospitalisée pour des décollements épidermiques nécrolytiques quasi-généralisés survenue le lendemain de l'application une solution de concentré de potasse sur tout le tégument. Cette solution avait été appliquée dans le but de traiter une éruption micropapuleuse prurigineuse généralisée (exanthème maculo-papuleux) survenue suite à a prise de cotrimoxazole. La réépidermisation était totale sans séquelle après un mois de suivi. Le diagnostic nécrolyse épidermique toxique ou syndrome de Lyell qui met souvent en jeu le pronostic vital avait été écarté devant la conservation de l'état général, l'absence d'atteinte muqueuse et la rapide cicatrisation. Certains traitements traditionnels ont fait la preuve au cours du temps de leur efficacité, mais un mésusage peut être à l'origine d'effets secondaires graves. PMID:26587148

Simulation d'ecoulements internes compressibles laminaires et turbulents par une methode d'elements finis

NASA Astrophysics Data System (ADS)

Rebaine, Ali

1997-08-01

Ce travail consiste en la simulation numerique des ecoulements internes compressibles bidimensionnels laminaires et turbulents. On s'interesse, particulierement, aux ecoulements dans les ejecteurs supersoniques. Les equations de Navier-Stokes sont formulees sous forme conservative et utilisent, comme variables independantes, les variables dites enthalpiques a savoir: la pression statique, la quantite de mouvement et l'enthalpie totale specifique. Une formulation variationnelle stable des equations de Navier-Stokes est utilisee. Elle est base sur la methode SUPG (Streamline Upwinding Petrov Galerkin) et utilise un operateur de capture des forts gradients. Un modele de turbulence, pour la simulation des ecoulements dans les ejecteurs, est mis au point. Il consiste a separer deux regions distinctes: une region proche de la paroi solide, ou le modele de Baldwin et Lomax est utilise et l'autre, loin de la paroi, ou une formulation nouvelle, basee sur le modele de Schlichting pour les jets, est proposee. Une technique de calcul de la viscosite turbulente, sur un maillage non structure, est implementee. La discretisation dans l'espace de la forme variationnelle est faite a l'aide de la methode des elements finis en utilisant une approximation mixte: quadratique pour les composantes de la quantite de mouvement et de la vitesse et lineaire pour le reste des variables. La discretisation temporelle est effectuee par une methode de differences finies en utilisant le schema d'Euler implicite. Le systeme matriciel, resultant de la discretisation spatio-temporelle, est resolu a l'aide de l'algorithme GMRES en utilisant un preconditionneur diagonal. Les validations numeriques ont ete menees sur plusieurs types de tuyeres et ejecteurs. La principale validation consiste en la simulation de l'ecoulement dans l'ejecteur teste au centre de recherche NASA Lewis. Les resultats obtenus sont tres comparables avec ceux des travaux anterieurs et sont nettement superieurs concernant les ecoulements turbulents dans les ejecteurs.

Environmental Assessment for the Construction of Facilities in Support of the 343d Training Squadron, 37th Training Group, Security Forces Apprentice Course at JBSA-Camp Bullis, Texas

DTIC Science & Technology

2012-11-01

ai n un de r g ov er nm en ta l j ur is di ct io n as a m ili ta ry tr ai ni ng fa ci lit y, a nd th er ef or e no lo ng...n o ne w co ns tru ct io n or re no va tio n w ou ld o cc ur ; t he re fo re , n o im pa ct s o n ai r q ua lit y w ou ld oc cu r. Te m...po ra ry a nd m in or in cr ea se s i n ai r p ol lu

Attosecond-resolution Hong-Ou-Mandel interferometry.

PubMed

Lyons, Ashley; Knee, George C; Bolduc, Eliot; Roger, Thomas; Leach, Jonathan; Gauger, Erik M; Faccio, Daniele

2018-05-01

When two indistinguishable photons are each incident on separate input ports of a beamsplitter, they "bunch" deterministically, exiting via the same port as a direct consequence of their bosonic nature. This two-photon interference effect has long-held the potential for application in precision measurement of time delays, such as those induced by transparent specimens with unknown thickness profiles. However, the technique has never achieved resolutions significantly better than the few-femtosecond (micrometer) scale other than in a common-path geometry that severely limits applications. We develop the precision of Hong-Ou-Mandel interferometry toward the ultimate limits dictated by statistical estimation theory, achieving few-attosecond (or nanometer path length) scale resolutions in a dual-arm geometry, thus providing access to length scales pertinent to cell biology and monoatomic layer two-dimensional materials.

100-OL-1 Operable Unit Field Portable X-Ray Fluorescence (XRF) Analyzer Pilot Study Plans

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bunn, Amoret L.; Fritz, Brad G.; Wellman, Dawn M.

A pilot study is being conducted to support the approval of the Remedial Investigation/Feasibility Study (RI/FS) Work Plan to evaluate the 100-OL-1 Operable Unit (OU) pre-Hanford orchard lands. Based on comments received by the U.S. Environmental Protection Agency (EPA) and Washington State Department of Ecology, the pilot study will evaluate the use of field portable X-ray fluorescence (XRF) spectrometry measurements for evaluating lead and arsenic concentrations on the soil surface as an indicator of past use of lead arsenate pesticide residue in the OU. The work will be performed in the field during the summer of 2014, and assist inmore » the planning for the characterization activities in the RI/FS.« less

Spectroscopic Studies of Lasing Transitions in the Diatomic Mercury Halides.

DTIC Science & Technology

1983-08-01

n ~! %A ;5. , -M .Ss 1 0l 5Ou - -% - :. - 0 ~ -0 P 0- -A - * SS a-zu e wC...0flr 04N 0* 1 0 t7 Ia >~ N 404 v .- =.. .5 - -~ N ~~ 06-~’ 0 p e u C’l0.f A 0Q to’ uu. co ? 1?C 0 Li.. A~~~ 0. 0 <- t3 .* ;1. ! .01. ~ * o~ OU >~ o0...0 4O 5O 3 0 N - ON =C ’AC 00 0 00 0 00 00 0 00 NN ~ *~ N . P ~ p 4 ~C 1 4 z Q - N Nc 0c Nc a- N o- P . IN N > 0 ~ 2 )fi il.C:.:: ** 0, o sa *.5o~5 o r

Superfund record of decision (EPA Region 4): Marine Corps Base (site 35), operable unit 10, Camp Lejeune, NC, September 22, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-01-01

This decision document presents the selected remedy for surficial groundwater for a portion of Operable Unit (OU) No. 10 (Site 35), Marine Corps Base (MCB), Camp Lejeune, North Carolina. Five Remedial Action Alternatives (RAAs) were evaluated as part of an interim remedial investigation/feasibility study for surficial groundwater at OU No. 10 (Site 35). These RAAs included RAA 1 (No Action), RAA 2 (No Action With Institutional Controls), RAA 3 (Groundwater Collection and On-site Treatment), RAA 4 (In Situ Air Sparging and Off-Gas Carbon Adsorption) and RAA 5 (In Well Aeration and Off-Gas Adsorption). After all five RAAs were compared tomore » established criteria, RAA 5 was selected as the preferred alternative.« less

Pharmacothérapie de la dépression chez les aînés

PubMed Central

Frank, Christopher

2014-01-01

Résumé Objectif Discuter du traitement pharmacologique de la dépression chez les personnes âgées, y compris le choix des antidépresseurs, le titrage de la dose, la surveillance de la réponse et des effets secondaires et le traitement des cas réfractaires. Sources des données Les lignes directrices de 2006 de la Canadian Coalition for Seniors’ Mental Health sur l’évaluation et le traitement de la dépression ont servi comme source principale. Pour recenser les articles publiés après les lignes directrices, on a procédé à une recherche documentaire dans MEDLINE de 2007 à 2012 à l’aide des expressions en anglais depression, treatment, drug therapy et elderly. Message principal Le but du traitement devrait être la rémission des symptômes. L’amélioration des symptômes peut être surveillée en fonction des objectifs du patient qu’on a identifiés ou en se servant d’outils cliniques comme le Patient Health Questionnaire–9. On devrait envisager le traitement en 3 étapes: l’étape du traitement aigu pour obtenir la rémission des symptômes, une étape de continuation pour prévenir la récurrence d’un même épisode de la maladie (rechute) et une étape de maintien (prophylaxie) pour prévenir de futurs épisodes (récurrence). Le dosage initial devrait être la moitié de la dose de départ habituelle chez l’adulte et il devrait être titré régulièrement jusqu’à ce que le patient réponde, jusqu’à ce que la dose maximale soit atteinte ou encore que les effets secondaires en limitent l’augmentation. Parmi les effets secondaires fréquents, on peut mentionner les chutes, la nausée, les étourdissements, les céphalées et, moins communément, l’hyponatrémie et des changements dans l’intervalle QT. Des stratégies pour changer ou augmenter les antidépresseurs sont présentées. Les patients plus âgés devraient être traités pendant au moins un an à compter de l’observation d’une amélioration clinique et ceux qui ont une dépression récurrente ou des symptômes sévères devraient continuer le traitement indéfiniment. La prise en charge de situations particulières comme une dépression profonde ou une dépression avec psychose est discutée, y compris le recours à une thérapie électroconvulsive. Les critères pour demander une consultation en psychiatrie gériatrique sont indiqués; par ailleurs, de nombreux médecins de famille n’ont pas aisément accès à une telle ressource ou à d’autres stratégies cliniques non pharmacologiques. Conclusion L’efficacité de la pharmacothérapie de la dépression n’est pas considérablement influencée par l’âge. L’identification de la dépression, le choix du traitement approprié, le tritrage des médicaments, la surveillance des effets secondaires et la durée suffisante du traitement amélioreront les résultats pour les patients plus âgés.

Evénements indésirables peropératoire: lecture critique du registre du bloc opératoire de l’hôpital militaire Moulay Ismail Meknès

PubMed Central

Kechna, Hicham; Ouzzad, Omar; Chkoura, Khalid; Loutid, Jaouad; Hachimi, Moulay Ahmed; Hanafi, Sidi Mohamed

2016-01-01

Introduction Malgré les importants progrès qui ont été faits dans le domaine de la sécurité en anesthésie, la morbidité (grave ou non, liée complètement ou partiellement à l’anesthésie) reste cependant fréquente, et aucun praticien n’est aujourd’hui à l’abri d’un accident. Dans le contexte actuel où la priorité est donnée à la formation, à l’amélioration de la qualité et de la sécurité des soins, la survenue d’un accident d’anesthésie au bloc opératoire est un événement extrêmement traumatisant. La crainte de poursuite, le contexte émotionnel rendent cette gestion parfois très difficile. Pour cette raison, elle doit faire l’objet d’une codification, à la manière des protocoles de bloc, avec trois grands axes de gestion: le patient victime, le personnel médical et paramédical impliqué et l’analyse de l’incident pour éviter une récidive. Méthodes Dans un but d’améliorer les soins prodigués au bloc opératoire nous avons établi un registre où sont consignés continuellement les différents incidents et accidents survenu soit en salle opératoire ou en salle de surveillance post interventionnelle. Une première lecture a été faite à l’occasion des Journées d'Enseignement Post Universitaire (JEPU) de Fès (Maroc) organisées en partenariat avec les JEPU de la Pitié salpêtrière de Paris à la faculté de Médecine et de Pharmacie de Fès sous le thème: «Les Situations Critiques Au Bloc Opératoire» les 17 et 18 Avril 2015. Résultats 1761 patients ont été admis aux différentes salles du bloc opératoire dont 96 en salle d’endoscopie et 17 sédations en radiologie. 29 patients (1.64%) ont présentés un incident et/ou un accident en péri opératoire. La plupart des effets indésirables sont survenus en per opératoire (58,6%). Dans 28,6% des cas en postopératoire immédiat ou en salle de surveillance post interventionnelle (SSPI). La plupart des complications survenues sont d’ordre respiratoire (34%) ou cardio vasculaire (31%). On a colligé 5 décès en périopératoire soit une mortalité de 0,28%. La détermination de la cause n’est pas toujours évidente. Le facteur humain serait responsable de 24% des incidents. Conclusion Cette observation illustre les différents événements indésirables survenus depuis la création de ce registre il y a 6 mois. Nous proposons une lecture critique de ce registre dans le seul souci est d’améliorer nos pratiques dans une perspective de renforcer la sécurité anesthésique. PMID:27795775

Hydrostratigraphic mapping of the Milford-Souhegan glacial drift aquifer, and effects of hydrostratigraphy on transport of PCE, Operable Unit 1, Savage Superfund Site, Milford, New Hampshire

USGS Publications Warehouse

Harte, Philip T.

2010-01-01

The Savage Municipal Well Superfund site in the Town of Milford, New Hampshire, was underlain by a 0.5-square mile plume (as mapped in 1994) of volatile organic compounds (VOCs), most of which consisted of tetrachloroethylene (PCE). The plume occurs mostly within highly transmissive stratified-drift deposits but also extends into underlying till and bedrock. The plume has been divided into two areas called Operable Unit 1 (OU1), which contains the primary source area, and Operable Unit 2 (OU2), which is defined as the extended plume area outside of OU1. The OU1 remedial system includes a low-permeability barrier wall that encircles the highest detected concentrations of PCE and a series of injection and extraction wells to contain and remove contaminants. The barrier wall likely penetrates the full thickness of the sand and gravel; in many places, it also penetrates the full thickness of the underlying basal till and sits atop bedrock.From 1998 to 2004, PCE concentrations decreased by an average of 80 percent at most wells outside the barrier wall. However, inside the barrier, PCE concentrations greater than 10,000 micrograms per liter (μg/L) still exist (2008). The remediation of these areas of recalcitrant PCE presents challenges to successful remediation.The U.S. Geological Survey (USGS), in cooperation with the New Hampshire Department of Environmental Services (NHDES) and the U.S. Environmental Protection Agency (USEPA), Region 1, is studying the solute transport of VOCs (primarily PCE) in contaminated groundwater in the unconsolidated sediments (overburden) of the Savage site and specifically assisting in the evaluation of the effectiveness of remedial operations in the OU1 area. As part of this effort, the USGS analyzed the subsurface stratigraphy to help understand hydrostratigraphic controls on remediation.A combination of lithologic, borehole natural gamma-ray and electromagnetic (EM) induction logging, and test drilling has identified 11 primary hydrostratigraphic units in OU1. These 11 units consist of several well-sorted sandy layers with some gravel that are separated by poorly sorted cobble layers with a fine-grained matrix. Collectively these units represent glacial sediments deposited by localized ice-margin fluctuations. For the most part, the units are semi-planar, particularly the cobble units, and truncated by an undulating bedrock surface. The lowermost unit is a basal till that ranges in thickness from zero to greater than 10 feet and mantles the bedrock surface.The 11 units have different lithologic and hydraulic characteristics. The hydraulic conductivity of the well-sorted sand and gravel units is typically greater than the conductivity of the poorly sorted cobble units and the basal till. The hydraulic conductivity ranges from 5 to greater than 500 feet per day. Lateral and vertical variation in lithology and hydraulic conductivity are inferred by variations in borehole natural gamma-ray counts and estimates of hydraulic conductivity.The comparison of hydrostratigraphic units with the spatial distribution of PCE concentrations suggests that solute transport away from source areas is primarily lateral within the permeable sandy units in the middle to lower parts of the aquifer. Along the centerline of the interior barrier area, highest PCE concentrations are in the sandy units to the east of suspected source areas.

Natural attenuation of chlorinated volatile organic compounds in ground water at Operable Unit 1, Naval Undersea Warfare Center, Division Keyport, Washington

USGS Publications Warehouse

Dinicola, Richard S.; Cox, S.E.; Landmeyer, J.E.; Bradley, P.M.

2002-01-01

The U.S. Geological Survey (USGS) evaluated the natural attenuation of chlorinated volatile organic compounds (CVOCs) in ground water beneath the former landfill at Operable Unit 1 (OU 1), Naval Undersea Warfare Center, Division Keyport, Washington. The predominant contaminants in ground water are trichloroethene (TCE) and its degradation byproducts cis-1,2-dichloroethene (cisDCE) and vinyl chloride (VC). The Navy planted two hybrid poplar plantations on the landfill in spring of 1999 to remove and control the migration of CVOCs in shallow ground water. Previous studies provided evidence that microbial degradation processes also reduce CVOC concentrations in ground water at OU 1, so monitored natural attenuation is a potential alternative remedy if phytoremediation is ineffective. This report describes the current (2000) understanding of natural attenuation of CVOCs in ground water at OU 1 and the impacts that phytoremediation activities to date have had on attenuation processes. The evaluation is based on ground-water and surface-water chemistry data and hydrogeologic data collected at the site by the USGS and Navy contractors between 1991 and 2000. Previously unpublished data collected by the USGS during 1996-2000 are presented. Natural attenuation of CVOCs in shallow ground water at OU 1 is substantial. For 1999-2000 conditions, approximately 70 percent of the mass of dissolved chlorinated ethenes that was available to migrate from the landfill was completely degraded in shallow ground water before it could migrate to the intermediate aquifer or discharge to surface water. Attenuation of CVOC concentrations appears also to be substantial in the intermediate aquifer, but biodegradation appears to be less significant; those conclusions are less certain because of the paucity of data downgradient of the landfill beneath the tide flats. Attenuation of CVOC concentrations is also substantial in surface water as it flows through the adjacent marsh and out to the tide flats. Attenuation processes other than dilution reduce the CVOC flux in marsh surface water by about 40 percent by the time the water discharges to the tide flats. Despite the importance of natural attenuation processes at reducing both the contaminant concentrations and the contaminant mass at OU 1, natural attenuation alone was not effective enough in the year 2000 to meet current numerical remediation goals for the site. That was in part due to the relatively short distance between the landfill and the adjacent marsh, and in part due to the extremely high CVOC concentrations directly beneath the landfill. Phytoremediation activities had some apparent effect on contaminant concentrations in ground water and surface water, but ground-water redox conditions to date (2000) were not affected by the February 1999 asphalt removal for tree planting. The poplar trees in the phytoremediation plantations were not yet mature in 2000, so the lack of discernible changes to date is understandable. Concentration changes of some redox-sensitive compounds suggest that increased recharge following asphalt removal diluted ambient landfill ground water. CVOC concentrations increased in some downgradient wells in both the northern and southern plantations after asphalt removal, whereas CVOC concentrations decreased in some upgradient wells in the southern plantation. A clear increase in CVOC concentrations in marsh surface water followed asphalt removal, apparently from increased contaminant discharge in ground water beneath the southern plantation. The results of the natural attenuation evaluation suggest than minor modifications to the current sampling plan may be beneficial to understanding the future impacts of phytoremediation and natural attenuation on the fate and distribution of CVOCs at OU 1.

Approche aux soins en milieu communautaire à des adultes ayant une déficience développementale

PubMed Central

Osmun, W.E.; Chan, Nelson; Solomon, Robert

2015-01-01

Résumé Objectif Passer en revue les obligations d’ordre médical, éthique et juridique dans les soins aux adultes ayant une déficience développementale (DD) qui vivent dans la communauté. Sources des données Des recherches ont été faites dans Google et MEDLINE à l’aide des mots disabled, disability, vulnerable et community. Les lois pertinentes ont fait l’objet d’un examen. Message principal Le traitement d’un patient ayant une DD varie en fonction de facteurs comme la pathogenèse du problème actuel du patient, ses affections concomitantes, la gravité de ses déficiences et ses soutiens sociaux habituels. Bien que l’on s’entende sur les bienfaits du transfert des soins institutionnels vers des soins communautaires pour les patients ayant une DD, il s’est révélé difficile de leur dispenser des soins de grande qualité en milieu communautaire. Par ailleurs, il existe peu de travaux de recherche sur les façons d’offrir efficacement des soins aux adultes ayant une DD. En tant que professionnels des soins primaires, les médecins de famille sont souvent le premier point de contact pour les patients et sont à la fois responsables de la coordination et de la continuité des soins. Compte tenu de l’importance accrue accordée aux soins préventifs et à la détection précoce des maladies, la participation active du patient revêt aussi une grande importance. Les valeurs et les objectifs du patient sont des éléments essentiels à prendre en compte, même s’ils vont à l’encontre de la bonne santé du patient ou des propres valeurs du clinicien. Les lois s’appliquant aux personnes vulnérables varient d’une province à l’autre. Par conséquent, l’obligation de signaler des mauvais traitements suspectés pourrait différer selon que la personne vulnérable habite dans un centre de soins ou la communauté, que la personne qui soupçonne le comportement abusif est un fournisseur de services ou un professionnel de la santé ou encore que les circonstances spécifiques répondent à la définition légale de mauvais traitement ou de négligence. Conclusion Les professionnels des soins primaires doivent dispenser aux adultes ayant une DD des soins empreints de compassion qui respectent les souhaits du patient.

Freestanding midwifery units versus obstetric units: does the effect of place of birth differ with level of social disadvantage?

PubMed Central

2012-01-01

Background Social inequity in perinatal and maternal health is a well-documented health problem even in countries with a high level of social equality. We aimed to study whether the effect of birthplace on perinatal and maternal morbidity, birth interventions and use of pain relief among low risk women intending to give birth in two freestanding midwifery units (FMU) versus two obstetric units in Denmark differed by level of social disadvantage. Methods The study was designed as a cohort study with a matched control group. It included 839 low-risk women intending to give birth in an FMU, who were prospectively and individually matched on nine selected obstetric/socio-economic factors to 839 low-risk women intending OU birth. Educational level was chosen as a proxy for social position. Analysis was by intention-to-treat. Results Women intending to give birth in an FMU had a significantly higher likelihood of uncomplicated, spontaneous birth with good outcomes for mother and infant compared to women intending to give birth in an OU. The likelihood of intact perineum, use of upright position for birth and water birth was also higher. No difference was found in perinatal morbidity or third/fourth degree tears, while birth interventions including caesarean section and epidural analgesia were significantly less frequent among women intending to give birth in an FMU. In our sample of healthy low-risk women with spontaneous onset of labour at term after an uncomplicated pregnancy, the positive results of intending to give birth in an FMU as compared to an OU were found to hold for both women with post-secondary education and the potentially vulnerable group of FMU women without post-secondary education. In all cases, women without post-secondary education intending to give birth in an FMU had comparable and, in some respects, more favourable outcomes when compared to women with the same level of education intending to give birth in an OU. In this sample of low-risk women, we found that the effect of intended place on birth outcomes did not differ with women’s level of education. Conclusion FMU care appears to offer important benefits for birthing women with no additional risk to the infant. Both for women with and without post-secondary education, intending to give birth in an FMU significantly increased the likelihood of a spontaneous, uncomplicated birth with good outcomes for mother and infant compared to women intending to give birth in an OU. All women should be provided with adequate information about different care models and supported in making an informed decision about the place of birth. PMID:22726575

Exploration of preterm birth rates associated with different models of antenatal midwifery care in Scotland: Unmatched retrospective cohort analysis.

PubMed

Symon, Andrew; Winter, Clare; Cochrane, Lynda

2015-06-01

preterm birth represents a significant personal, clinical, organisational and financial burden. Strategies to reduce the preterm birth rate have had limited success. Limited evidence indicates that certain antenatal care models may offer some protection, although the causal mechanism is not understood. We sought to compare preterm birth rates for mixed-risk pregnant women accessing antenatal care organised at a freestanding midwifery unit (FMU) and mixed-risk pregnant women attending an obstetric unit (OU) with related community-based antenatal care. unmatched retrospective 4-year Scottish cohort analysis (2008-2011) of mixed-risk pregnant women accessing (i) FMU antenatal care (n=1107); (ii) combined community-based and OU antenatal care (n=7567). Data were accessed via the Information and Statistics Division of the NHS in Scotland. Aggregates analysis and binary logistic regression were used to compare the cohorts׳ rates of preterm birth; and of spontaneous labour onset, use of pharmacological analgesia, unassisted vertex birth, and low birth weight. Odds ratios were adjusted for age, parity, deprivation score and smoking status in pregnancy. after adjustment the 'mixed risk' FMU cohort had a statistically significantly reduced risk of preterm birth (5.1% [n=57] versus 7.7% [n=583]; AOR 0.73 [95% CI 0.55-0.98]; p=0.034). Differences in these secondary outcome measures were also statistically significant: spontaneous labour onset (FMU 83.9% versus OU 74.6%; AOR 1.74 [95% CI 1.46-2.08]; p<0.001); minimal intrapartum analgesia (FMU 53.7% versus OU 34.4%; AOR 2.17 [95% CI 1.90-2.49]; p<0.001); spontaneous vertex delivery (FMU 71.9% versus OU 63.5%; AOR 1.46 [95% CI 1.32-1.78]; p<0.001). Incidence of low birth weight was not statistically significant after adjustment for other variables. There was no significant difference in the rate of perinatal or neonatal death. given this study׳s methodological limitations, we can only claim associations between the care model and or chosen outcomes. Although both cohorts were mixed risk, differences in risk levels could have contributed to these findings. Nevertheless, the significant difference in preterm birth rates in this study resonates with other research, including the recent Cochrane review of midwife-led continuity models. Because of the multiplicity of risk factors for preterm birth we need to explore the salient features of the FMU model which may be contributing to this apparent protective effect. Because a randomised controlled trial would necessarily restrict choice to pregnant women, we feel that this option is problematic in exploring this further. We therefore plan to conduct a prospective matched cohort analysis together with a survey of unit practices and experiences. Copyright © 2015 Elsevier Ltd. All rights reserved.

Le conflit fémoro-acétabulaire et la coxarthrose

PubMed Central

Zhang, Charlie; Li, Linda; Forster, Bruce B.; Kopec, Jacek A.; Ratzlaff, Charles; Halai, Lalji; Cibere, Jolanda; Esdaile, John M.

2015-01-01

Objectif Expliquer la présentation clinique, les observations à l’examen physique, les critères diagnostiques et les options de prise en charge du conflit fémoroacétabulaire (CFA). Sources des données Une recherche documentaire a été effectuée dans PubMed pour trouver des articles pertinents sur la pathogenèse, le diagnostic, le traitement et le pronostic du CFA. Message principal Depuis les dernières années, on reconnaît de plus en plus que le CFA est un précurseur potentiel et une étiologie importante des douleurs à la hanche dans la population adulte et de la coxarthrose idiopathique plus tard dans la vie. Le conflit fémoro-acétabulaire désigne un ensemble d’anomalies morphologiques osseuses de l’articulation de la hanche qui se traduit par un contact anormal durant le mouvement. Le CFA par effet came concerne une proéminence osseuse non sphérique du col fémoral proximal ou de la jonction tête-col. Le CFM par effet tenaille désigne une couverture acétabulaire excessive par-dessus la tête du fémur, qui peut se produire en raison de diverses variantes morphologiques. Les patients qui ont un CFA présentent une douleur inguinale antérieure chronique, profonde ou lancinante, le plus souvent en position assise, durant ou après une activité. Les patients peuvent aussi ressentir des douleurs occasionnelles aiguës durant l’activité. Il faut procéder à une anamnèse approfondie portant notamment sur l’incidence de traumatismes ou la fréquence de l’exercice. Il faut aussi faire un examen physique complet des hanches, de la région lombaire et de l’abdomen pour évaluer d’autres causes de douleurs inguinales antérieures. Le diagnostic de CFA est confirmé par radiographie. Le conflit fémoro-acétabulaire peut être pris en charge selon une approche conservatrice comportant du repos, la modification des activités, des médicaments et de la physiothérapie ou encore être traité par intervention chirurgicale. Conclusion Le conflit fémoro-acétabulaire est une cause importante de douleurs antérieures à l’aine. Une détection précoce et une intervention rapide par un médecin de soins primaires sont essentielles pour atténuer la morbidité et éviter la progression du CFA.

L’investigation de la contusion myocardique pour la fracture sternale à l’urgence

PubMed Central

Audette, Jean-Sébastien; Émond, Marcel; Scott, Hugh; Lortie, Gilles

2014-01-01

Résumé Objectif Décrire la pratique d’acquisition d’un électrocardiogramme (ECG) initial, d’ECG de contrôle ou d’un monitoring équivalent et du dosage des troponines chez les patients avec une fracture sternale évalués au département d’urgence ou par un médecin de première ligne. Type d’étude Étude rétrospective descriptive multicentrique. Contexte Deux centres académiques de traumatologie de la région de Québec au Canada. Participants 54 patients ayant subi une fracture sternale traumatique. Interventions Évaluation de l’acquisition d’ECG initial et à 6 heures post-traumatisme ou un monitoring équivalent ainsi que le dosage des troponines sanguines. Principaux paramètres à l’étude En ce qui concerne l’ECG, les critères de comparaison de qualité furent sélectionnés à partir d’opinions d’experts rapportées dans quatre études. L’utilisation d’un ECG initial et de contrôle 6 heures post-traumatisme ou d’un monitoring cardiaque de 6 heures représente la pratique recommandée par la plupart de ceux-ci pour le diagnostic de la contusion myocardique dans la fracture sternale. L’utilisation des troponines I sanguines, 4 à 8 heures suivant un traumatisme thoracique, a également été proposée par certains auteurs comme méthode de détection efficace des arythmies significatives secondaires à la contusion myocardique. Des analyses descriptives univariées et des tests de chi-carré furent effectués. Une valeur P < ,05 fut considérée significative. Résultats Trente-neuf (72 %) patients ont été évalués initialement avec un ECG, tandis que 18 (33 %) de ces patients ont eu une évaluation par ECG ou monitoring cardiaque après 6 heures à l’urgence. Seize patients (30 %) ont été évalués à l’aide du dosage des troponines I. Deux patients (4 %) ont présenté des anomalies électrocardiographiques et un seul patient (2 %) a présenté des troponines I élevées. Conclusion Les urgentologues doivent augmenter leur utilisation de l’ECG comme outil diagnostic initial et de contrôle pour les patients ayant subi une fracture sternale traumatique afin de détecter la contusion myocardique et l’arythmie. L’utilisation de la troponinémie, de concert avec l’ECG, est également suggérée dans cette population pour l’identification des patients à risque de complications secondaires à leur contusion myocardique.

Summary of Meteorological Observations, Surface (SMOS), Pensacola, Florida.

DTIC Science & Technology

1984-02-01

1 o ot TD 3__- 7o 0lU4 .9 iop -- I f 61 goo * 94 1.6 b 22 Ne o_ TT 9,! oU .4’ 2.2 3.6 2.1 .2 SOS SOS S * ___, 301_____ o__ 15,3* 9.2 SW .0 1 __ 3 1...2 1 93 C 1Q3 - 2t 1000 9 9 o ,.j -7 𔃻 94 ’ 4* . 5 Soft t 4. 94I 9f , ’ o. • no SW * ~ ~ ~ ’)~ 𔄁 .9 9". 46 9’.. -41195 ’,’., .2 07 > 700 * . 7 A...34. ’Iloa 29 *U 6S*2 3 .0I I, I".1 -a. 0 .1 g. 01 IS,.0 1 I 0" 93o3 I or! 2So.3 . 7%.’ oft 11 II tD ’:ca t’r. 0 6 e .; 92oe4 4 45 C.7 -? o ’, TOTALS 9 5 2

Influence of electronegativity on the electronic structures and stabilities of microclusters of carbides MC_n (M : transition, rare-earth or normal element, n < 10)

NASA Astrophysics Data System (ADS)

Leleyter, M.

1991-10-01

MC_n, clusters (n < 10) produced from carbides by various experimental techniques (SIMS, SSMS, LAMMA, Knudsen effusion, etc.) show strong alternations in their emission intensities I(MC^+_n) according to the parity of the carbon atom number n. Maxima take place for odd n (“odd" alternations) if M = H, F, Cl or Fe, Ni, Rh, Ir, Pt or for even n (“even" alternations) if M = B, Si, Ba, Ge or Sc, Ti, V, Cr, Y, Zr, La, Ce, W, Th, U or even the ions exist only for even n (Nd, Dy, Ho, Er). Moreover, only CO, C_3O, CN and C_3N are known for O and N. Such phenomena are due to the stability properties of the clusters themselves (“correspondence rule") and can be interpreted with the Pitzer and Clementi model (sp hybridization in Hückel approximation): the clusters are assumed to be linear chains of “cumulene" type :C=C=..C=C=M and the alternations in the relative stabilities of these chains are mainly due to the fact that the HOMO (highest occupied molecular orbital) of the clusters lies in a double degenerate π level band. Now HOMO may be either full or half-filled, and an aggregate with a complete (or almost complete) HOMO is more stable than an aggregate with a half-filled HOMO. Consequently, the number of π electrons is governing the parity effect in the stability alternations. However, this number is depending on the number of σ electrons of the chain and besides, for the transition or rare-earth metals, on the positions of the dσ and degenerate dδ levels due to the M atom, which are governed by Pauling's electronegativity (EN) of atom M. For transition or lanthanide metals, the alternations are “even" if EN le 1.7 (deficient d electron-elements: columns IIIA to VIIA; empty dσ and δ levels) or “odd" in the reverse case (rich d electron elements: column VIIIA bonding dσ and δ levels). For normal elements, the limit of EN seems to be the EN of C (2.5) and the alternations are “even" if EN le 2.5 or “odd" in the other case. Thus it is possible to infer a likely electronic configuration of the MC_n clusters and 2 tables give the compared electronic structures of these clusters for normal or transition elements. Such a kind of structure is only able to explain the parity effect origin of the MC_n clusters and even enable to foreknow for transition or rare-earth metal carbides which are not studied yet if the alternations will be “even" (EN le 1.7) or “odd". Les agrégats MC_n obtenus à partir de carbures par diverses méthodes expérimentales (SIMS, SSMS, vaporisation laser, effusion de Knudsen à haute température, etc.) présentent des alternances dans leurs intensités d'émission I(MC^+_n) avec maximums pour n impair si M = H, F, CI ou Fe, Ni, Rh, Ir, Pt ou au contraire pour n pair si M = B, Si, Ba, Ge ou Sc, Ti, V, Cr, Y, Zr, La, Ce, W, Th, U ou même n'existent que pour n pair (Nd, Dy, Ho, Er). D'autre part, seuls sont connus CO, C_3O, CN et C_3N pour l'oxygène et l'azote. Ces phénomènes sont interprétés tout d'abord à l'aide de la règle bien connue de correspondance qui relie de fortes (resp. faibles) intensités ou fréquences d'émissions d'ions MC^+_n à de fortes (resp. faibles) stabilités des amas correspondants. En second lieu, ces résultats s'expliquent dans le cadre du modèle de Pitzer et Clementi (hybridation sp en théorie de Hückel) corroboré par des calculs CNDO: on suppose que les amas MC^+_n sont des chaînes linéaires C^+_n portant un atome d'impureté M en bout de chaîne. Dans ces conditions, les alternances de stabilités relatives des MC_n proviennent de ce que l'orbitale moléculaire la plus élevée (“ HOMO ”) se trouve dans une bande niveaux π doublement dégénérés et qu'à une orbitale π complète (4 électrons) correspond une plus forte stabilité de l'amas que si l'orbitale est incomplète. Or le nombre d'électrons π d'une chaîne MC_n est gouverné par le nombre de niveaux σ liants et en outre pour les éléments de transition ou de terres rares, par la position du niveau dσ et celle du niveau δ dégénérés dus à la présence de l'atome M. Dans le cas des éléments normaux, si M est plus électronégatif que C (EN = 2,5), l'orbitale sσ_M sera liante (2 électrons) alors qu'elle sera antiliante (vide) dans le cas contraire, et entraînera donc une différence de 2 électrons σ ou π, donc un changement de sens des alternances. Le cas spécial de H peut aussi s'expliquer dans ce cadre. Les éléments de transition pour leur part, se scindent en 2 groupes suivant que leur électronégativité EN est supérieure à 1,7 (éléments ayant beaucoup d'électrons d : colonne VIIIA ; niveaux δ et dσ liants) ou non (peu d'électrons d : colonnes IIIA et terres rares à VIIA ; niveaux δ et dσ vides). Nous donnons deux tableaux récapitulant la structure comparée des niveaux des agrégats MC_n pour les éléments normaux ou de transition. Ce type de structure peut seul expliquer l'origine des alternances des amas MC_n et permet même de prévoir pour des carbures de transition ou de terres rares non encore étudiés, si les alternances seront “ paires ” (EN le 1,7 ) ou “ impaires ” (EN > 1,7).

Cateteres venosos centrais de inserção periférica: alternativa ou primeira escolha em acesso vascular?

PubMed Central

Di Santo, Marcelo Kalil; Takemoto, Diogo; Nascimento, Robert Guimarães; Nascimento, Ariele Milano; Siqueira, Érika; Duarte, Caio Túlio; Jovino, Marco Antônio Caldas; Kalil, Jorge Agle

2017-01-01

Resumo Contexto Os cateteres venosos centrais de inserção periférica (PICC) são dispositivos intravenosos, introduzidos através de uma veia superficial ou profunda da extremidade superior ou inferior até o terço distal da veia cava superior ou proximal da veia cava inferior. Apresentam maior segurança para infusão de soluções vesicantes/irritantes e hiperosmolares, antibioticoterapia, nutrição parenteral prolongada (NPT) e uso de quimioterápicos; demonstram reduzido risco de infecção em comparação a outros cateteres vasculares e maior relação custo/benefício se comparados ao cateter venoso de inserção central (CVCIC). Objetivos Apresentar os resultados de implantes de PICCs ecoguiados e posicionados por fluoroscopia realizados no Hospital e Maternidade São Luiz (HMSL) Itaim, Rede D’or, Brasil. Métodos Estudo prospectivo, não randomizado, realizado entre fevereiro de 2015 e novembro de 2016. Utilizou-se protocolo pré-estabelecido pela instituição em casos de solicitação de acesso vascular. Foram analisadas indicações, doenças prevalentes, tipo do cateter implantado, sucesso técnico, complicações relacionadas ao cateter, e estabelecidos critérios de inclusão e exclusão. Resultados Solicitados 256 acessos vasculares, sendo implantados 236 PICCs (92,1%) e 20 CVCICs (7,9%). Principais indicações: antibioticoterapia prolongada (52,0%), NPT (19,3%) e acesso venoso difícil (16,0%). Houve sucesso técnico em 246 cateteres implantados (96,1%). A veia basílica direita foi a principal veia puncionada em 192 pacientes (75,0%), seguida da braquial direita em 28 pacientes (10,9%). Conclusões O implante dos PICCs ecoguiados e posicionados por fluoroscopia demonstrou baixa incidência de complicações, reduzidos índices de infecção e é seguro e eficaz em casos de acessos vasculares difíceis, sendo esses cateteres considerados dispositivos de escolha em acesso vascular central.

Interstrain variation in cardiac and respiratory adaptation to repeated ozone and particulate matter exposures.

PubMed

Hamade, Ali K; Tankersley, Clarke G

2009-04-01

Increased ambient particulate matter (PM) is associated with adverse cardiovascular and respiratory outcomes, as demonstrated by epidemiology studies. Several studies have investigated the role of copollutants, such as ozone (O(3)), in this association. It is accepted that physiological adaptation involving the respiratory system occurs with repeated exposures to O(3). We hypothesize that adaptation to PM and O(3) varies among different inbred mouse strains, and cardiopulmonary adaptation to O(3) is a synchronized response between the cardiac and respiratory systems. Heart rate (HR), HR variability (HRV), and the magnitude and pattern of breathing were simultaneously measured by implanted telemeters and by plethysmography in three inbred mouse strains: C57Bl/6J (B6), C3H/HeJ (HeJ), and C3H/HeOuJ (OuJ). Physiological responses were assessed during dual exposures to filtered air (FA), O(3) (576 +/- 32 parts/billion), and/or carbon black (CB; 556 +/- 34 mug/m(3)). Exposures were repeated for 3 consecutive days. While each strain showed significant reductions in HR during CB with O(3) preexposure (O(3)CB) on day 1, prominent HRV responses were observed in only HeJ and OuJ mice. Each strain also differed in their adaptation profile in response to repeated O(3)CB exposures. Whereas B6 mice showed rapid adaptation in HR after day 1, HeJ mice generally showed more moderate HR and HRV adaptation after day 2 of exposure. Unlike either B6 or HeJ strains, OuJ mice showed little evidence of HR or HRV adaptation to repeated O(3)CB exposure. Adaptation profiles between HR regulation and breathing characteristics were strongly correlated, but these associations also varied significantly among strains. These findings suggest that genetic factors determine the responsivity and adaptation of the cardiac and respiratory systems to repeated copollutant exposures. During O(3)CB exposure, adaptation of cardiac and respiratory systems is markedly synchronized, which may explain a potential mechanism for adverse effects of PM on heart function.

Spectroscopie du Furanne et du Thiophene Par Diffusion Inelastique D'electrons

NASA Astrophysics Data System (ADS)

Lotfi, Said

Nous avons etudie les molecules de furanne ( rm C_4H_4O) et de thiophene (rm C_4H_4O) au moyen de la spectroscopie de diffusion inelastique d'electrons. Pour (rm C_4H_4O), les spectres realises dans differentes conditions d'energie d'impact et d'angle de diffusion contiennent des singularites ou des families de pics correspondant a: (1) des vibrations de l'etat fondamental dans le domaine 0-0.5 eV, (2) des etats triplets ^3 B_1 et ^3 A_1 qui dominent la region 3-5.5 eV, (3) des etats de valences, entre 5 et 10 eV, dont certains son accompagnes de progressions vibrationnelles, soit ~ A _1B_2, ~ B ^1A_1 et ~ C ^1A_1, (4) toujours entre 5 et 10 eV, deux series de Ryhdberg (rm 1a_2to nda_2 et rm 1a_2to npb_2) qui convergent vers la premiere limite d'ionisation de la molecule, avec une progression vibrationnelle associee au mdoe nu_4 pour la seconde, et une troisieme serie (rm 2b_1to nsa_1 ) convergent vers la seconde limite d'ionisation accompagnee de la progression de mode nu _1. Pour rm C_4H_4S, nos spectres presentent les memes etats de vibration et les memes etats triplets que pour rm C_4H _4O. Nous avons releve egalement, dans la region de 5 a 10 eV, des etats de valence ~ A ^1A_1 (ou ~ A ^1B_2), ~ B ^1A_1 (ou ~ B ^1B _2) et ~ C ^1A_1 (ou ~ C ^1B_2). Pour la premiere fois, par la spectroscopie de diffusion inelastique d'electrons, de nombreux pics ont ete identifies et attribues, dans le cadre de ce travail. Il s'agit, notamment, des etats de vibration de l'etat electronique fondamental de ces molecules et egalement de certains etats de Rydberg dans le cas du furanne.

La prévention et le traitement des infections bactériennes chez les enfants aspléniques ou hypospléniques

PubMed Central

1999-01-01

L’asplénie, qu’elle soit fonctionnelle ou anatomique, s’associe à un accroissement du risque d’infection potentiellement fatale ou constituant un danger de septicémie postsplénectomie (SPS). En raison du risque accru de bactériémie par des bactéries encapsulées chez les enfants aspléniques, la vaccination visant à prévenir une infection au Streptococcus pneumoniae, à l’Haemophilus influenzae de type b (Hib) et au Neiserria meningitidis est recommandée. Malgré la prévalence croissante de S pneumoniae pénicillinorésistant, on recommande aussi l’usage de pénicilline prophylactique chez les enfants aspléniques de moins de cinq ans, et pendant au moins un an après une splénectomie. La poursuite de la prophylaxie antibiotique après cette période dépend de la situation clinique de chaque enfant et de la prévalence de S pneumoniae pénicillinorésistant au sein de la collectivité. Lorsque des enfants aspléniques font de la fièvre ou présentent des symptômes non spécifiques, ils devraient faire l’objet d’une évaluation immédiate. Si on présume la présence de septicémie bactérienne, il faut procéder à une analyse du sang et des autres liquides organiques pertinents et entreprendre sur-le-champ une antibiothérapie à large spectre par voie parentérale, laquelle doit agir également contre les souches de S pneumoniae présentes dans la collectivité. Chez les enfants aspléniques souffrant d’une septicémie foudroyante à S pneumoniae, le taux de mortalité est élevé, malgré l’utilisation rapide d’une antibiothérapie convenable, d’où l’importance des mesures préventives.

On Ensino de Astronomia nas Cidades de Ribeirão Pires e Rio Grande da Serra

NASA Astrophysics Data System (ADS)

Faria, R. Z.; Voelzke, M. R.

2007-08-01

Apesar da astronomia ser um dos temas indicados pelos Parâmetros Curriculares Nacionais, observa-se que poucas mudanças ocorreram desde a implementação do mesmo em sala de aula. A presente pesquisa diz respeito sobre como os tópicos de astronomia estão sendo abordados pelos professores no ensino médio. Optou-se por aplicar um questionário com os professores que ministram a disciplina de física. Os mesmos trabalham em escolas estaduais situadas nas cidades de Ribeirão Pires e Rio Grande da Serra, ambas subordinadas a Diretoria de Ensino de Mauá, no Estado de São Paulo. O questionário foi aplicado durante o 2° semestre de 2006. Até o momento os resultados são preliminares. Dos 82,0% dos professores que responderam ao questionário no município de Rio Grande da Serra, 66,7% não aplicaram nenhum tópico de astronomia, 77,8% não utilizaram qualquer tipo de programa computacional, 66,7% não utilizaram laboratório, que 77,8% nunca levaram os alunos a museus e ou planetários e que 66,7% não indicaram qualquer tipo de revista ou livro sobre astronomia aos seus alunos. No município de Ribeirão Pires, 53,3% dos professores responderam ao questionário, destes 75,0% não aplicaram nenhum tópico de astronomia, 93,8% não utilizaram qualquer tipo de programa computacional, 75,0% não utilizaram laboratório, 81,3% nunca levaram os alunos a museus e ou planetário e 56,3% não indicaram qualquer tipo de revista ou livro sobre astronomia ao seus alunos. Apesar da maioria dos professores reconhecerem que o conteúdo de astronomia influi na formação do jovem, os mesmos não incluem o tema em seus planejamentos escolares.

Interstrain variation in cardiac and respiratory adaptation to repeated ozone and particulate matter exposures

PubMed Central

Hamade, Ali K.; Tankersley, Clarke G.

2009-01-01

Increased ambient particulate matter (PM) is associated with adverse cardiovascular and respiratory outcomes, as demonstrated by epidemiology studies. Several studies have investigated the role of copollutants, such as ozone (O3), in this association. It is accepted that physiological adaptation involving the respiratory system occurs with repeated exposures to O3. We hypothesize that adaptation to PM and O3 varies among different inbred mouse strains, and cardiopulmonary adaptation to O3 is a synchronized response between the cardiac and respiratory systems. Heart rate (HR), HR variability (HRV), and the magnitude and pattern of breathing were simultaneously measured by implanted telemeters and by plethysmography in three inbred mouse strains: C57Bl/6J (B6), C3H/HeJ (HeJ), and C3H/HeOuJ (OuJ). Physiological responses were assessed during dual exposures to filtered air (FA), O3 (576 ± 32 parts/billion), and/or carbon black (CB; 556 ± 34 μg/m3). Exposures were repeated for 3 consecutive days. While each strain showed significant reductions in HR during CB with O3 preexposure (O3CB) on day 1, prominent HRV responses were observed in only HeJ and OuJ mice. Each strain also differed in their adaptation profile in response to repeated O3CB exposures. Whereas B6 mice showed rapid adaptation in HR after day 1, HeJ mice generally showed more moderate HR and HRV adaptation after day 2 of exposure. Unlike either B6 or HeJ strains, OuJ mice showed little evidence of HR or HRV adaptation to repeated O3CB exposure. Adaptation profiles between HR regulation and breathing characteristics were strongly correlated, but these associations also varied significantly among strains. These findings suggest that genetic factors determine the responsivity and adaptation of the cardiac and respiratory systems to repeated copollutant exposures. During O3CB exposure, adaptation of cardiac and respiratory systems is markedly synchronized, which may explain a potential mechanism for adverse effects of PM on heart function. PMID:19158411

La pelade par plaques

PubMed Central

Spano, Frank; Donovan, Jeff C.

2015-01-01

Résumé Objectif Présenter aux médecins de famille des renseignements de base pour faire comprendre l’épidémiologie, la pathogenèse, l’histologie et l’approche clinique au diagnostic de la pelade par plaques. Sources des données Une recension a été effectuée dans PubMed pour trouver des articles pertinents concernant la pathogenèse, le diagnostic et le pronostic de la pelade par plaques. Message principal La pelade par plaques est une forme de perte pileuse auto-immune dont la prévalence durant une vie est d’environ 2 %. Des antécédents personnels ou familiaux de troubles auto-immuns concomitants, comme le vitiligo ou une maladie de la thyroïde, peuvent être observés dans un petit sous-groupe de patients. Le diagnostic peut souvent être posé de manière clinique en se fondant sur la perte de cheveux non cicatricielle et circulaire caractéristique, accompagnée de cheveux en « point d’exclamation » en périphérie chez ceux dont le problème en est aux premiers stades. Le diagnostic des cas plus complexes ou des présentations inhabituelles peut être facilité par une biopsie et un examen histologique. Le pronostic varie largement et de mauvais résultats sont associés à une apparition à un âge précoce, une perte importante, la variante ophiasis, des changements aux ongles, des antécédents familiaux ou des troubles auto-immuns concomitants. Conclusion La pelade par plaques est une forme auto-immune de perte de cheveux périodiquement observée en soins primaires. Les médecins de famille sont bien placés pour identifier la pelade par plaques, déterminer la gravité de la maladie et poser le diagnostic différentiel approprié. De plus, ils sont en mesure de renseigner leurs patients à propos de l’évolution clinique de la maladie ainsi que du pronostic général selon le sous-type de patients.

Automobile Crash Sensor Signal Processor

DOT National Transportation Integrated Search

1973-11-01

The crash sensor signal processor described interfaces between an automobile-installed doppler radar and an air bag activating solenoid or equivalent electromechanical device. The processor utilizes both digital and analog techniques to produce an ou...

Hong-Ou-Mandel Interference with a Single Atom.

PubMed

Ralley, K A; Lerner, I V; Yurkevich, I V

2015-09-14

The Hong-Ou-Mandel (HOM) effect is widely regarded as the quintessential quantum interference phenomenon in optics. In this work we examine how nonlinearity can smear statistical photon bunching in the HOM interferometer. We model both the nonlinearity and a balanced beam splitter with a single two-level system and calculate a finite probability of anti-bunching arising in this geometry. We thus argue that the presence of such nonlinearity would reduce the visibility in the standard HOM setup, offering some explanation for the diminution of the HOM visibility observed in many experiments. We use the same model to show that the nonlinearity affects a resonant two-photon propagation through a two-level impurity in a waveguide due to a "weak photon blockade" caused by the impossibility of double-occupancy and argue that this effect might be stronger for multi-photon propagation.

Simple circular odor chart for characterization of trace amounts of odorants discharged from thirteen odor sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoshika, Y.; Nihei, Y.; Muto, G.

1981-04-01

A simple circular odor chart is proposed for the explanation of the relationship between sensory responses (to odor quality and intensity) to odors and chemical analysis data of the odorants responsible for each odor discharged from thirteen odor sources. The odorants were classified into eight odorant groups and were analyzed by a systematic gas chromatographic (GC) technique. The characterization of the trace amounts of the odorants was carried out by using the values of a new proposed unit (pOU) based on the ratio of detected concentration to recognition threshold value. The calculated pOU values of the eight groups were plottedmore » in circular charts. It was found that the shape and size of each circular odor chart represent the quality and the intensity of each odor.« less

Formes hémorragiques graves de la fièvre de la vallée du Rift: à propos de 5 cas

PubMed Central

Salem, Mohamed Lemine Ould; Baba, Sidi El Wafi Ould; Fall-Malick, Fatimetou Zahra; Boushab, Boushab Mohamed; Ghaber, Sidi Mohamed; Mokhtar, Abdelwedoud

2016-01-01

La fièvre de la vallée du Rift (FVR) est une arbovirose due à un virus à ARN appartenant à la famille de Bunyaviridae (genre phlebovirus). C'est une zoonose touchant principalement les animaux mais pouvant aussi contaminer l'homme, soit directement par la manipulation des viandes ou avortons d'animaux malades ou indirectement par la piqure de moustiques infectées (Aèdes sp, anophèles sp, Culex sp). Dans la majorité des cas, l'infection humaine à FVR est asymptomatique, mais elle peut également se manifester par un syndrome fébrile modérée d’évolution favorable. Néanmoins, certains patients peuvent développer un syndrome hémorragique et/ou des lésions neurologiques d’évolution mortelle. Nous décrivons l’évolution de cinq cas de patients atteints de la FVR, admis dans le service de médecine interne du Centre Hospitalier National de Nouakchott (Mauritanie), le mois d'Octobre 2015 et présentant tous, un syndrome hémorragique dans un contexte fébrile. L’évolution n’était favorable que pour 2 des cinq patients. Les 3 autres sont décédés, deux dans un tableau de choc hémorragique et dans un état de choc septique. PMID:27642413

Récidive après dix ans de tumeur de granulosa de l’ovaire: à propos de deux cas et revue de la littérature

PubMed Central

Majdoul, Soufya; Tawfiq, Nezha; Bourhaleb, Zouhour; Naqos, Nora; Taleb, Amina; Bouchbika, Zineb; Benchakroun, Nadia; Jouhadi, Hassan; Sahraoui, Souha; Benider, Abdelatif

2016-01-01

Les tumeurs à cellules de la granulosa (TG) de l’ovaire sont des tumeurs rares appartenant au groupe des tumeurs des cordons sexuels et du stroma. Elles représentent 0,6 à 3 % de l’ensemble des tumeurs de l’ovaire et 5 % des tumeurs malignes On distingue deux types: le type juvénile (TGJ) qui se caractérise par son agressivité et le type adulte (TGA) qui est le type le moins agressif et le plus fréquent. Les rechutes de TG de l'ovaire surviennent généralement dans les cinq ans, elles sont rarement sous forme de métastases péritonéales ou locales. Bien que, des options de traitement y compris la chirurgie avec ou sans chimiothérapie et ou radiothérapie ont été rapportés pour le traitement des récidives des TG, il n'y a aucune prise en charge standardisée de récidive de cette maladie. Ici, nous rapportons notre stratégie thérapeutique dans la prise en charge des récidives tardives, après dix ans, de la TG sous forme de carcinose péritonéale pour deux patientes avec une revue de la littérature. PMID:28154722

La dysplasie fibreuse: état des lieux

PubMed Central

Akasbi, Nessrine; Abourazzak, Fatima Ezzahra; Talbi, Sofia; Tahiri, Latifa; Harzy, Taoufik

2015-01-01

La dysplasie fibreuse des os est une affection osseuse bénigne congénitale mais non héréditaire, où l'os normal est remplacé par un tissu fibreux renfermant une ostéogenèse immature. Elle est due à une mutation du gène GNAS 1sur le chromosome 20q13, une mutation activatrice de la sous-unité α de la protéine G. C'est une pathologie qui est le plus souvent silencieuse, de découverte fortuite sur une radiographie standard ou révélée par une douleur osseuse ou une fracture pathologique. L'imagerie et l'histologie, quand elle est nécessaire, permettent d’établir le diagnostic. Bien qu'il ne s'agisse pas d'une tumeur, elle est souvent classée dans la catégorie des tumeurs osseuses bénignes pour des raisons de diagnostic différentiel radiographique et anatomopathologique. Elle peut être monostotique ou polyostotique. L'approche thérapeutique est essentiellement symptomatique. Quelques publications récentes ont suggéré l'intérêt majeur d'un bisphosphonate, en particulier le pamidronate, qui diminuerait les douleurs et stimulerait une reminéralisation progressive des zones ostéolytiques chez les patients traités. D'autres traitements tels que la thérapie ciblée sont en cours d’évaluation. PMID:26401215

Feline dry eye syndrome of presumed neurogenic origin: a case report.

PubMed

Sebbag, Lionel; Pesavento, Patricia A; Carrasco, Sebastian E; Reilly, Christopher M; Maggs, David J

2018-01-01

A 14-year-old female spayed Abyssinian cat, which about 1 year previously underwent thoracic limb amputation, radiotherapy and chemotherapy for an incompletely excised vaccine-related fibrosarcoma, was presented for evaluation of corneal opacity in the left eye (OS). The ocular surface of both eyes (OU) had a lackluster appearance and there was a stromal corneal ulcer OS. Results of corneal aesthesiometry, Schirmer tear test-1 (STT-1) and tear film breakup time revealed corneal hypoesthesia, and quantitative and qualitative tear film deficiency OU. Noxious olfactory stimulation caused increased lacrimation relative to standard STT-1 values suggesting an intact nasolacrimal reflex. Various lacrimostimulants were administered in succession; namely, 1% pilocarpine administered topically (15 days) or orally (19 days), and topically applied 0.03% tacrolimus (47 days). Pilocarpine, especially when given orally, was associated with notable increases in STT-1 values, but corneal ulceration remained/recurred regardless of administration route, and oral pilocarpine resulted in gastrointestinal upset. Tacrolimus was not effective. After 93 days, the cat became weak and lame and a low thyroxine concentration was detected in serum. The cat was euthanized and a necropsy performed. Both lacrimal glands were histologically normal, but chronic neutrophilic keratitis and reduced conjunctival goblet cell density were noted OU. The final diagnosis was dry eye syndrome (DES) of presumed neurogenic origin, associated with corneal hypoesthesia. This report reinforces the importance of conducting tearfilm testing in cats with ocular surface disease, as clinical signs of DES were different from those described in dogs.

A distinctive dual-channel quorum-sensing system operates in Vibrio anguillarum.

PubMed

Croxatto, Antony; Pride, John; Hardman, Andrea; Williams, Paul; Cámara, Miguel; Milton, Debra L

2004-06-01

Many bacterial cells communicate using diffusible signal molecules to monitor cell population density via a process termed quorum sensing. In marine Vibrio species, the Vibrio harveyi-type LuxR protein is a key player in a quorum-sensing phosphorelay cascade, which controls the expression of virulence, symbiotic and survival genes. Previously, we characterized Vibrio anguillarum homologues of LuxR (VanT) and LuxMN (VanMN) and, in this study, we have identified homologues of LuxPQ (VanPQ) and LuxOU (VanOU). In contrast to other Vibrio species, vanT was expressed at low cell density and showed no significant induction as the cell number increased. In addition, although the loss of VanO increased vanT expression, the loss of VanU, unexpectedly, decreased it. Both VanN and VanQ were required for repression of vanT even in a vanU mutant, suggesting an alternative route for VanNQ signal transduction other than via VanU. VanT negatively regulated its own expression by binding and repressing the vanT promoter and by binding and activating the vanOU promoter. The signal relay results in a cellular response as expression of the metalloprotease, empA, was altered similar to that of vanT in all the mutants. Consequently, the V. anguillarum quorum-sensing phosphorelay systems work differently from those of V. harveyi and may be used to limit rather than induce vanT expression.

Water quality assessment of highly polluted rivers in a semi-arid Mediterranean zone Oued Fez and Sebou River (Morocco)

NASA Astrophysics Data System (ADS)

Perrin, J. L.; Raïs, N.; Chahinian, N.; Moulin, P.; Ijjaali, M.

2014-03-01

Oued Fez (one of the Sebou River tributaries - Morocco) allowed us to study and quantify the effect of the lack of wastewater treatment on surface water quality in semi-arid hydrological context. The analysis is based on field data collected from June 2009 to December 2011. Concentration and load patterns of nitrogen, phosphorus and chromium (used in the processing of leather) are compared in stable hydrological conditions during low flow and high flow periods in an eight-location sampling network. The Oued Fez and the Sebou River are characterised by severe pollution downstream from the city of Fez, particularly TN (mainly NH4 and Norg), TP (mainly Ppart) and TCr. The most polluted sites are those directly under the influence of domestic and industrial waste water inputs, particularly tannery effluents. Obviously, the concentrations measured at these locations are above all environmental quality standards. Pollutant loads are very heavy in the Sebou River and can contaminate the river course for kilometres. Moreover, as the water of the Sebou River is used for the irrigation of vegetables, serious problems of public health could arise. A better understanding of contaminant dynamics and self-purifying processes in these rivers will help implement actions and steps aimed at improving water quality in the Sebou River, which is the primary water supply source in Morocco and is used for agricultural and industrials purposes as well as for drinking water.

REMEDIAL INVESTIGATION REPORT FOR THE 200-CW-5 U POND & Z DITCHES & 200-CW-2 S POND & 200-SCW-R T POND & 200-SC-1 STEAM CONDENSATE GROUP OU

DOE Office of Scientific and Technical Information (OSTI.GOV)

BAUER, R.G.

2004-08-05

The purpose of this remedial investigation (RI) report is to evaluate the data generated during the RI and other characterization activities at the 200-CW-5 Operable Unit (OU) to (1) determine if sufficient data have been collected to support risk assessment and remedial decision making, (2) estimate risk at the representative sites based on data collected during the RI and on other existing data, (3) determine the need to proceed with a feasibility study (FS), and (4) determine which constituents and site-specific considerations need to be addressed in the FS. This RI report also provides data to support the evaluation ofmore » alternatives in the FS with regard to meeting potential applicable or relevant and appropriate requirements, risk reduction, and potentially significant data gaps (if any). This RI report includes an evaluation of the baseline risk using characterization data generated during the RI and significant data from other investigations (e.g., historical data from the 216-U-10 Pond and the 216-Z-1D, 216-Z-11, 216-U-14, and 216-Z-19 Ditches). Data generated during the RI will support the closeout of waste sites in the 200-CW-5 OU, as well as the waste sites in the 200-CW-2,200-CW-4, and 200-SC-1 consolidated OUs.« less

Ground-water hydrology and simulation of ground-water flow at Operable Unit 3 and surrounding region, U.S. Naval Air Station, Jacksonville, Florida

USGS Publications Warehouse

Davis, J.H.

1998-01-01

The Naval Air Station, Jacksonville (herein referred to as the Station), occupies 3,800 acres adjacent to the St. Johns River in Duval County, Florida. Operable Unit 3 (OU3) occupies 134 acres on the eastern side of the Station and has been used for industrial and commercial purposes since World War II. Ground water contaminated by chlorinated organic compounds has been detected in the surficial aquifer at OU3. The U.S. Navy and U.S. Geological Survey (USGS) conducted a cooperative hydrologic study to evaluate the potential for ground water discharge to the neighboring St. Johns River. A ground-water flow model, previously developed for the area, was recalibrated for use in this study. At the Station, the surficial aquifer is exposed at land surface and forms the uppermost permeable unit. The aquifer ranges in thickness from 30 to 100 feet and consists of unconsolidated silty sands interbedded with local beds of clay. The low-permeability clays of the Hawthorn Group form the base of the aquifer. The USGS previously conducted a ground-water investigation at the Station that included the development and calibration of a 1-layer regional ground-water flow model. For this investigation, the regional model was recalibrated using additional data collected after the original calibration. The recalibrated model was then used to establish the boundaries for a smaller subregional model roughly centered on OU3. Within the subregional model, the surficial aquifer is composed of distinct upper and intermediate layers. The upper layer extends from land surface to a depth of approximately 15 feet below sea level; the intermediate layer extends from the upper layer down to the top of the Hawthorn Group. In the northern and central parts of OU3, the upper and intermediate layers are separated by a low-permeability clay layer. Horizontal hydraulic conductivities in the upper layer, determined from aquifer tests, range from 0.19 to 3.8 feet per day. The horizontal hydraulic conductivity in the intermediate layer, determined from one aquifer test, is 20 feet per day. An extensive stormwater drainage system is present at OU3 and the surrounding area. Some of the stormwater drains have been documented to be draining ground water from the upper layer of the surficial aquifer, whereas other drains are only suspected to be draining ground water. The subregional model contained 78 rows and 148 columns of square model cells that were 100 feet on each side. Vertically, the surficial aquifer was divided into two layers; layer 1 represented the upper layer and layer 2 represented the intermediate layer. Steady-state ground-water flow conditions were assumed. The model was calibrated to head data collected on October 29 and 30, 1996. After calibration, the model matched all 67 measured heads to within the calibration criterion of 1 foot; and 48 of 67 simulated heads (72 percent) were within 0.5 foot. Model simulated recharge rates ranged from 0.4 inch per year in areas that were largely paved to 13.0 inches per year in irrigated areas. Simulated hydraulic conductivities in the upper layer at OU3 ranged from 0.5 foot per day in the north to 1.0 foot per day in the south. Simulated vertical leakance between the upper and intermediate layers ranged from 1.0x10-6 per day in an area with low-permeability clays to 4.3x10-2 per day in an area that had been dredged. Simulated transmissivities in the intermediate layer ranged from 25 feet squared per day in an area of low-permeability channel-fill deposits to a high of 1,200 feet squared per day in areas covering most of OU3. Simulated riverbed conductances ranged from 4 to 60 feet squared per day and simulated bottom conductances of leaking stormwater drains ranged from 5 to 20 feet squared per day. The direction and velocity of ground-water flow was determined using particle-tracking techniques. Ground-water flow in the upper layer was generally eastward toward the St. Johns River. However, leaking stormwat

Infant mortality by color or race from Rondônia, Brazilian Amazon.

PubMed

Gava, Caroline; Cardoso, Andrey Moreira; Basta, Paulo Cesar

2017-04-10

To analyze the quality of records for live births and infant deaths and to estimate the infant mortality rate for skin color or race, in order to explore possible racial inequalities in health. Descriptive study that analyzed the quality of records of the Live Births Information System and Mortality Information System in Rondônia, Brazilian Amazonian, between 2006-2009. The infant mortality rates were estimated for skin color or race with the direct method and corrected by: (1) proportional distribution of deaths with missing data related to skin color or race; and (2) application of correction factors. We also calculated proportional mortality by causes and age groups. The capture of live births and deaths improved in relation to 2006-2007, which required lower correction factors to estimate infant mortality rate. The risk of death of indigenous infant (31.3/1,000 live births) was higher than that noted for the other skin color or race groups, exceeding by 60% the infant mortality rate in Rondônia (19.9/1,000 live births). Black children had the highest neonatal infant mortality rate, while the indigenous had the highest post-neonatal infant mortality rate. Among the indigenous deaths, 15.2% were due to ill-defined causes, while the other groups did not exceed 5.4%. The proportional infant mortality due to infectious and parasitic diseases was higher among indigenous children (12.1%), while among black children it occurred due to external causes (8.7%). Expressive inequalities in infant mortality were noted between skin color or race categories, more unfavorable for indigenous infants. Correction factors proposed in the literature lack to consider differences in underreporting of deaths for skin color or race. The specific correction among the color or race categories would likely result in exacerbation of the observed inequalities. Analisar a qualidade dos registros de nascidos vivos e de óbitos infantis e estimar a taxa de mortalidade infantil segundo cor ou raça, a fim de explorar iniquidades étnico-raciais em saúde. Estudo descritivo que analisou a qualidade dos registros do Sistema de Informações sobre Nascidos Vivos e do Sistema de Informações sobre Mortalidade em Rondônia, Amazônia brasileira, entre 2006-2009. As taxas de mortalidade infantil foram estimadas nas categorias de cor ou raça, pelo método direto, e corrigidas por: (1) distribuição proporcional dos óbitos com cor ou raça ignorada; e (2) aplicação de fatores de correção. Efetuou-se também o cálculo da mortalidade proporcional por causas e grupos etários. Entre 2008-2009, a captação de nascimentos e óbitos melhorou em relação aos anos de 2006-2007, requerendo fatores de correção menores para estimar a taxa de mortalidade infantil. O risco de morte de crianças indígenas (31,3/1.000 nascidos vivos) foi maior que o registrado nos demais grupos de cor ou raça, excedendo em 60% a mortalidade infantil média no estado (19,9/1.000 nascidos vivos). As crianças pretas apresentaram as maiores taxas de mortalidade infantil neonatal, enquanto as indígenas apresentaram as maiores taxas de mortalidade infantil pós-neonatal. Observou-se que 15,2% dos óbitos indígenas foram por causas mal definidas, enquanto nos demais grupos não ultrapassaram 5,4%. A mortalidade infantil proporcional por doenças infecciosas e parasitárias foi maior entre indígenas, ao passo que entre crianças pretas, sobressaíram as causas externas (8,7%). Observaram-se expressivas iniquidades na mortalidade infantil entre as categorias de cor ou raça, com situação mais desfavorável às crianças indígenas. Os fatores de correção propostos na literatura não consideram diferenças na subenumeração de óbitos entre as categorias de cor ou raça. A correção específica entre as categorias de cor ou raça provavelmente resultaria em exacerbação das iniquidades observadas.

At Risk for Kidney Disease?

MedlinePlus

... in Adults Preventing CKD What If My Kidneys Fail? Clinical Trials Anemia High Blood Pressure Pour les personnes atteintes de diabète ou d’hypertension artérielle Heart Disease Mineral & Bone Disorder Causes of Chronic Kidney ...

International Airline Quality Measurement

DOT National Transportation Integrated Search

1998-01-01

Historically, airline quality has been measured through the use of surveys that ask the consumers to make a comparison between expectations and outcomes. This method was informative but very cumbersome in a rapidly changing environment. This paper ou...

Le bilingue, surhomme ou infirme? (The Bilingual, Superman or Cripple?)

ERIC Educational Resources Information Center

Tournier, Michel

1975-01-01

Discusses good translation techniques, "true bilingualism," and the effect of bilingualism on cognitive development. (Text is in French.) Available from Lloyds Bank Chambers, 91 Newington Causeway, London SE1 6BN, England. (AM)

Interventions et techniques de diagnostic prénatal visant l'obtention d'un prélèvement fœtal à des fins diagnostiques : Risques et avantages pour la mère et le fœtus.

PubMed

Wilson, R Douglas; Gagnon, Alain; Audibert, François; Campagnolo, Carla; Carroll, June

2016-12-01

Offrir aux fournisseurs de soins de maternité et à leurs patientes des lignes directrices factuelles contemporaines en ce qui concerne les services de counseling traitant des risques et des avantages maternels propres à la tenue des interventions diagnostiques prénatales orientées par échographie (et/ou des techniques permettant l'établissement d'un diagnostic génétique) nécessaires dans les cas où il a été établi pendant la période prénatale que la grossesse serait exposée à des risques, ainsi qu'en ce qui concerne la prise de décisions subséquentes quant à la prise en charge de la grossesse (questions abordant des aspects tels que le niveau du fournisseur de soins obstétricaux, la surveillance prénatale, le lieu où devraient se dérouler les soins et l'accouchement, et la décision de poursuivre ou d'interrompre la grossesse). La présente directive clinique se limite aux services de counseling traitant des risques et des avantages maternels, et aux décisions en matière de prise en charge de la grossesse pour les femmes qui nécessitent (ou qui envisagent) la mise en œuvre d'une intervention ou d'une technique effractive orientée par échographie aux fins de l'établissement d'un diagnostic prénatal. Femmes enceintes identifiées, à la suite de la mise en œuvre de protocoles établis de dépistage prénatal (taux sériques maternels ± imagerie, résultats d'analyse de l'ADN acellulaire indiquant des risques élevés, résultats anormaux au moment de l'imagerie fœtale diagnostique ou antécédents familiaux de troubles héréditaires), comme étant exposées à un risque accru d'anomalie génétique fœtale. Ces femmes pourraient nécessiter ou demander des services de counseling au sujet des risques et des avantages pour la grossesse de la tenue d'une intervention effractive orientée par échographie visant à déterminer l'étiologie, le diagnostic, et/ou la pathologie de possibles anomalies fœtales. RéSULTATS: La littérature publiée a été récupérée par l'intermédiaire de recherches menées dans Medline, PubMed et The Cochrane Library jusqu'en juin 2014 au moyen d'un vocabulaire contrôlé (« prenatal diagnosis », « amniocentesis », « chorionic villi sampling », « cordocentesis ») et de mots clés (« prenatal screening », « prenatal genetic counselling », « post-procedural pregnancy loss rate ») appropriés. Les résultats ont été restreints aux analyses systématiques, aux études observationnelles et aux essais comparatifs randomisés / essais cliniques comparatifs publiés en anglais entre janvier 1985 et juin 2014. Les recherches ont été mises à jour de façon régulière et intégrées à la directive clinique jusqu'en juin 2014. La littérature grise (non publiée) a été identifiée par l'intermédiaire de recherches menées dans les sites Web d'organismes s'intéressant à l'évaluation des technologies dans le domaine de la santé et d'organismes connexes, dans des collections de directives cliniques, dans des registres d'essais cliniques et auprès de sociétés de spécialité médicale nationales et internationales. La qualité des résultats a été évaluée au moyen des critères décrits dans le rapport du Groupe d'étude canadien sur les soins de santé préventifs (Tableau 1). AVANTAGES, DéSAVANTAGES ET COûTS: Consentement éclairé de la patiente, transfert des connaissances, évaluation du risque génétique prénatal, soulagement de l'anxiété, création d'anxiété, défense des droits, compréhension du dépistage fœtal, limites du dépistage fœtal, choix en matière de prise en charge de la grossesse, complication de la grossesse ou fausse couche, soins opportuns et améliorés pour l'accouchement d'un enfant présentant une morbidité reconnue. RECOMMANDATIONS. Copyright © 2016. Published by Elsevier Inc.

Fibrillation auriculaire et activité physique

PubMed Central

Bosomworth, N. John

2015-01-01

Résumé Objectif Examiner les données probantes portant sur les effets de divers niveaux d’activité physique sur l’incidence de fibrillation auriculaire (FA) dans la population générale et chez les athlètes d’endurance. Sources des données Une recherche a initialement été menée sur PubMed à l’aide des titres MeSH ou des mots-de-texte anglais (avec descripteur de zone de recherche TIAB [title and abstract]) atrial fibrillation et exercise ou physical activity ou athlet* ou sport*, sans filtre additionnel. Le système GRADE (grading of recommendations, assessment, development, and evaluation) a été utilisé pour tirer les conclusions au sujet de la qualité et du niveau de preuve. Sélection des études Aucune étude d’intervention n’est ressortie de la recherche. Les études d’observation ont alors été jugées acceptables et, bien que des études prospectives de cohortes à long terme de plus grande envergure auraient été préférables, des essais cas-témoins ou transversaux ont aussi été inclus dans cette révision. Synthèse Les données disponibles laissent croire à un lien proportionnel à la dose entre l’exercice plus intense et l’incidence réduite de FA chez les femmes. Il en va de même pour les hommes dont le niveau d’activité physique est de faible à modéré. Chez les hommes seulement, l’activité intense est associée à un risque accru de FA et ce, dans la plupart des études, mais pas la totalité d’entre elles. Ce risque est modéré, le rapport de risque instantané étant de 1,29 dans l’une des études de meilleure qualité. Le risque de FA chez la plupart des personnes régulièrement actives est plus faible que le risque observé dans la population sédentaire appariée. Conclusion La fibrillation auriculaire est probablement moins fréquente à mesure que le niveau d’activité physique augmente, la relation dose-réponse étant démontrable. À toutes les intensités, l’exercice doit être encouragé pour ses effets sur le bien-être physique et la réduction de la mortalité. Chez les hommes qui pratiquent des activités vigoureuses, les effets bénéfiques sur la FA pourraient disparaître et le risque pourrait surpasser celui observé dans la population sédentaire; cependant les données probantes à cet effet ne sont ni robustes ni constantes. Ces hommes devraient être mis au courant de cette hausse modeste du risque s’ils choisissent de poursuivre leurs activités physiques vigoureuses.

The Samoa tsunami of 29 September 2009: Field survey in Tonga and preliminary modeling

NASA Astrophysics Data System (ADS)

Okal, E. A.; Fritz, H. M.; Borrero, J. C.

2010-05-01

The two northernmost islands in Tonga, Niuatoputapu and Tafahi, were hit hard by the Samoa tsunami of 29 September 2009, with considerable devastation on the former, where nine people were killed. A surveying team consisting of HMF and EAO visited the islands in late November. On Niuatoputapu, we document extreme inundation reaching 600 m on the Southern coast, and a complete overrun of the Northeastern tip at Hikuniu Point, with flow depths reaching 10 m for a total wave height of 16 m. The forests were totally destroyed, and apparently provided no barrier to waves of such height. On the small stratovolcano island of Tafahi, run-up reached 22.8 m on the lee side of the island. The three villages of Niuatoputapu were provided a relative level of protection by the fringing coral reef present on the Northern shore. Seven of the nine victims were riding in a pick-up truck on a road parallel to the coast. One point, with run-up of 4 m, was also surveyed on the island of Niuafo'ou, 200 km further West. We present a number of numerical simulations, using several models of the seismic source, which correctly predict enhanced amplitudes in the direction of the Northern Tonga Islands as a result of focusing by shallow bathymetry at the bend marking the Northern end of the Tonga subduction zone.

IMPROVING WATERBORNE DISEASE SURVEILLANCE

EPA Science Inventory

Public health surveillance has played a key role in controlling the spread of communicable disease and identifying the need for specific publich health practices, such as the filteration and chlorination of drinking water supplies. However, the characteristics of waterborne ou...

Algeria

NASA Image and Video Library

2008-09-04

The impermanent waterways shown here from NASA EarthKAM are part of Oued Irharrhar, which appear to be carrying sulfur yellow and iron red deposits. The city of Amguid is located on these waterways, and all lie in the Mouydir Mountains in Algeria.

Physical Parameters of Components in Close Binary Systems. V

NASA Astrophysics Data System (ADS)

Zola, S.; Kreiner, J. M.; Zakrzewski, B.; Kjurkchieva, D. P.; Marchev, D. V.; Baran, A.; Rucinski, S. M.; Ogloza, W.; Siwak, M.; Koziel, D.; Drozdz, M.; Pokrzywka, B.

2005-12-01

The paper presents combined spectroscopic and photometric orbital solutions for ten close binary systems: CN And, V776 Cas, FU Dra, UV Lyn, BB Peg, V592 Per, OU Ser, EQ Tau, HN UMa and HT Vir. The photometric data consist of new multicolor light curves, while the spectroscopy has been recently obtained within the radial velocity program at the David Dunlap Observatory (DDO). Absolute parameters of the components for these binary systems are derived. Our results confirm that CN And is not a contact system. Its configuration is semi-detached with the secondary component filling its Roche lobe. The configuration of nine other systems is contact. Three systems (V776 Cas, V592 Per and OU Ser) have high (44-77%) and six (FU Dra, UV Lyn, BB Peg, EQ Tau, HN UMa and HT Vir) low or intermediate (8-32%) fill-out factors. The absolute physical parameters are derived.

Odour and ammonia emissions from intensive poultry units in Ireland.

PubMed

Hayes, E T; Curran, T P; Dodd, V A

2006-05-01

Odour and ammonia emissions were measured from three broiler, two layer and two turkey houses in Ireland. The broiler units gave a large range of odour and ammonia emission rates depending on the age of the birds and the season. A considerable variation between the odour and ammonia emission rates was evident for the two layer units which may have been due to the different manure handling systems utilised in the houses. There was relatively little difference in the odour and ammonia emissions from the two turkey houses. As a precautionary principle, odour emission rates utilised in atmospheric dispersion models should use the maximum values for broilers and turkeys (1.22 and 10.5 ou(E) s(-1) bird(-1) respectively) and the mean value for the layers depending on the manure handling system used (0.47 or 1.35 ou(E) s(-1) bird(-1)).

Measurement of photon indistinguishability to a quantifiable uncertainty using a Hong-Ou-Mandel interferometer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thomas, Peter J.; Cheung, Jessica Y.; Chunnilall, Christopher J.

2010-04-10

We present a method for using the Hong-Ou-Mandel (HOM) interference technique to quantify photon indistinguishability within an associated uncertainty. The method allows the relative importance of various experimental factors affecting the HOM visibility to be identified, and enables the actual indistinguishability, with an associated uncertainty, to be estimated from experimentally measured quantities. A measurement equation has been derived that accounts for the non-ideal performance of the interferometer. The origin of each term of the equation is explained, along with procedures for their experimental evaluation and uncertainty estimation. These uncertainties are combined to give an overall uncertainty for the derived photonmore » indistinguishability. The analysis was applied to measurements from an interferometer sourced with photon pairs from a parametric downconversion process. The measured photon indistinguishably was found to be 0.954+/-0.036 by using the prescribed method.« less

État de santé des nouveaux réfugiés à Toronto, en Ontario

PubMed Central

Redditt, Vanessa J.; Graziano, Daniela; Janakiram, Praseedha; Rashid, Meb

2015-01-01

Résumé Objectif Déterminer la prévalence de certaines maladies chroniques parmi les nouveaux réfugiés et la présence ou non d’une variation en fonction de facteurs démographiques clés. Conception Revue rétrospective de dossiers. Contexte Clinique de soins primaires pour patients réfugiés à Toronto, en Ontario. Participants Au total, 1063 patients réfugiés inscrits à la clinique entre décembre 2011 et juin 2014. Principaux paramètres à l’étude Données démographiques (âge, sexe et pays de naissance); prévalence de résultats anormaux au test Pap, d’anémie, d’élévation de la tension artérielle (TA) et de présence de marqueurs de prédiabète ou de diabète (glycémie aléatoire, glycémie à jeun ou taux d’hémoglobine A1c élevés). Résultats Plus de la moitié de nos patients étaient des femmes (56 %) et l’âge médian était de 29 ans. Les réfugiés étaient nés dans 87 pays différents. Les pays d’origine du plus grand nombre de réfugiés étaient la Hongrie (210 patients), la Corée du Nord (119 patients) et le Nigéria (93 patients). La plupart des patients sont arrivés à titre de demandeurs d’asile (92 %) plutôt qu’à titre de réfugiés pris en charge par le gouvernement (5 %). Dans l’ensemble, 11 % des patientes ayant subi un test Pap ont obtenu des résultats de cytologie cervicale anormaux, ce taux étant le plus élevé parmi les patientes originaires d’Asie (26 %; p = 0,028). La prévalence d’anémie parmi les enfants de moins de 15 ans était de 11 %; et elle était de 14 % parmi les enfants de moins de 5 ans. Environ 25 % des femmes de plus de 15 ans étaient anémiques, ce taux était le plus élevé parmi les patientes originaires d’Afrique (37 %; p < 0,001). L’élévation de la TA a été observée chez 30 % des adultes de plus de 15 ans, ce taux étant supérieur parmi les patients de sexe masculin (38 %; p < 0,001) et originaires d’Europe (42 %; p < 0,001). Les marqueurs biologiques de prédiabète ou de diabète ont été détectés chez 8 % des patients de plus de 15 ans, ce taux étant supérieur parmi les patients originaires d’Europe (15 %; p = 0,026). Conclusion Cette étude a mis en évidence un fardeau notable de maladies chroniques parmi les réfugiés, y compris d’anémie, d’élévation de la TA et de piètre contrôle de la glycémie, de même que de résultats anormaux de cytologie cervicale. Ces résultats mettent en lumière l’importance de permettre aux réfugiés d’accéder à des soins primaires complets, en mettant l’accent sur la prévention et la prise en charge des maladies chroniques en plus de la prise en charge des maladies infectieuses.

Prise en charge d’un afflux massif de brûles lors d’une situation de catastrophe par incendie au Maroc

PubMed Central

Siah, S.; Hatimi, E.M.; Ihrai, H.; Drissi Kamili, N.

2012-01-01

Summary La brûlure est l’une des lésions les plus fréquemment rencontrées lors de catastrophes naturelles ou lors de catastrophes d’origine humaine (incendies de lieux publics d’origine accidentelle, ou en temps de guerre ou encore lors d’attentats terroristes). La prise en charge et le triage de brûlés en nombre reste un problème difficile; ceci souligne la nécessité d’une réflexion et de prévisions de ces crises en insistant sur la formation des médecins et des soignants. Les défis à relever sont multiples: les soins aux brûlés requièrent un nombre important de personnel qualifié; les évacuations doivent être planifiées en fonction de la gravité de la brûlure et des lésions associées; les stocks et lots de dotation (en particulier en topiques anti-infectieux et en cristalloïdes) doivent être suffisants et adéquats. Les services hospitaliers de l’Hôpital Militaire d’Instruction Mohammed V de Rabat doivent pouvoir être rapidement adaptés pour accueillir et surtout isoler ces patients. L’hypothèse d’une catastrophe par incendie avec afflux massif de brûlés à l’hôpital militaire d’instruction Mohammed V de Rabat ne doit laisser place à aucune improvisation. PMID:23467075

Feline dry eye syndrome of presumed neurogenic origin: a case report

PubMed Central

Sebbag, Lionel; Pesavento, Patricia A; Carrasco, Sebastian E; Reilly, Christopher M; Maggs, David J

2018-01-01

Case summary A 14-year-old female spayed Abyssinian cat, which about 1 year previously underwent thoracic limb amputation, radiotherapy and chemotherapy for an incompletely excised vaccine-related fibrosarcoma, was presented for evaluation of corneal opacity in the left eye (OS). The ocular surface of both eyes (OU) had a lackluster appearance and there was a stromal corneal ulcer OS. Results of corneal aesthesiometry, Schirmer tear test-1 (STT-1) and tear film breakup time revealed corneal hypoesthesia, and quantitative and qualitative tear film deficiency OU. Noxious olfactory stimulation caused increased lacrimation relative to standard STT-1 values suggesting an intact nasolacrimal reflex. Various lacrimostimulants were administered in succession; namely, 1% pilocarpine administered topically (15 days) or orally (19 days), and topically applied 0.03% tacrolimus (47 days). Pilocarpine, especially when given orally, was associated with notable increases in STT-1 values, but corneal ulceration remained/recurred regardless of administration route, and oral pilocarpine resulted in gastrointestinal upset. Tacrolimus was not effective. After 93 days, the cat became weak and lame and a low thyroxine concentration was detected in serum. The cat was euthanized and a necropsy performed. Both lacrimal glands were histologically normal, but chronic neutrophilic keratitis and reduced conjunctival goblet cell density were noted OU. Relevance and novel information The final diagnosis was dry eye syndrome (DES) of presumed neurogenic origin, associated with corneal hypoesthesia. This report reinforces the importance of conducting tearfilm testing in cats with ocular surface disease, as clinical signs of DES were different from those described in dogs. PMID:29318025

Restrictive orbital myofibroblastic sarcoma in a cat--cross-sectional imaging (MRI & CT) appearance, treatment, and outcome.

PubMed

Thomasy, Sara M; Cissell, Derek D; Arzi, Boaz; Vilches-Moure, Jose G; Lo, Winnie Y; Wisner, Erik R; Dubielzig, Richard R; Maggs, David J

2013-07-01

A 16-year-old spayed female cat was evaluated for lagophthalmos and chronic exposure keratitis in both eyes. Ophthalmic examination revealed upper and lower eyelid entropion of the left eye (OS) and markedly decreased retropulsion, restricted eye movement, marked episcleral congestion, and severe keratitis of both eyes (OU). Magnetic resonance imaging of both orbits revealed extensive, irregular, contrast-enhancing tissue without evidence of osteolysis considered compatible with diffuse inflammatory tissue. Feline herpesvirus DNA was not detected in conjunctival samples. Partial temporary tarsorrhaphies were placed OU, and the cat was treated with topically administered erythromycin ointment OU, orally administered famciclovir and prednisolone, and sublingually administered buprenorphine. Little improvement was noted after 2 weeks. Six weeks after initial presentation, a left exenteration was performed and histopathology was consistent with idiopathic sclerosing orbital pseudotumor (ISOP). Ten weeks after initial presentation, the patient represented for weight loss and jaw pain. Computed tomography demonstrated disease progression in the right orbit and the patient was euthanized. Histopathology of the decalcified skull revealed an aggressive and highly infiltrative mass involving the right orbit with extension to the maxilla, hard palate, nasal cavity and gingiva most consistent with feline restrictive orbital myofibroblastic sarcoma (FROMS). Clinical data from this patient support the reclassification of ISOP as FROMS. MRI and CT may provide supportive evidence for FROMS, but histopathology is necessary for definitive diagnosis. Aggressive and early surgical treatment, including bilateral exenteration, with adjunctive radiotherapy and/or chemotherapy should be considered for patients with FROMS. © 2013 American College of Veterinary Ophthalmologists.

A eficiência de formação estelar em Musca

NASA Astrophysics Data System (ADS)

Hickel, G. R.; Vilas-Boas, J. W. S.; Roberto, A. J.., Jr.; Khan, R. P.

2003-08-01

Apresentamos os resultados de um survey no infravermelho próximo (bandas J e H), executado no Laboratório Nacional de Astrofísica, na direção da nuvem escura em forma de filamento de Musca (observamos ao longo de todo o filamento, além de todas as fontes pontuais IRAS e/ou fontes ROSAT brilhantes a uma distância de 2o da nuvem). Nosso objetivo é determinar a eficiência de formação estelar para esta nuvem escura (massa de estrelas formadas/massa da nuvem), procurando por objetos estelares jovens de pequena massa no seu interior e/ou evoluídos o suficiente para estarem afastados do local de nascimento, mas ainda mostrando características de objetos pré-seqüência principal como emissão de raios-X e excesso de emissão no infravermelho próximo. Este survey não estabeleceu nenhum viés na seleção de fontes pontuais IRAS ou fontes ROSAT, uma vez que a imensa maioria das fontes pontuais IRAS nesta região têm qualidade de fluxo ruim. Os candidatos a objetos estelares jovens foram selecionados pelo excesso no índice de cor (J-H), descontados os efeitos da extinção interestelar na linha de visada, determinada através da emissão estendida no infravermelho distante (IRAS). Estimativas de massa foram feitas para estes candidatos, através da relação massa-luminosidade, para calcular a eficiência de formação estelar de Musca.

Feline restrictive orbital myofibroblastic sarcoma in a cat – Cross sectional imaging (MRI & CT) appearance, treatment and outcome

PubMed Central

Thomasy, Sara M.; Cissell, Derek D.; Arzi, Boaz; Vilches-Moure, Jose G.; Lo, Winnie Y.; Wisner, Erik R.; Dubielzig, Richard R.; Maggs, David J.

2012-01-01

Case Description A 16-year-old spayed female cat evaluated for lagophthalmos and chronic exposure keratitis in both eyes. Clinical Findings Ophthalmic examination revealed upper and lower eyelid entropion of the left eye (OS) and markedly decreased retropulsion, restricted eye movement, marked episcleral congestion, and severe keratitis of both eyes (OU). Magnetic resonance imaging of both orbits revealed extensive, irregular, contrast-enhancing tissue without evidence of osteolysis considered compatible with diffuse inflammatory tissue. Feline herpesvirus DNA was not detected in conjunctival samples. Treatment and Outcome Partial temporary tarsorrhaphies were placed OU and the cat was treated with topically administered erythromycin ointment OU, orally administered famciclovir and prednisolone, and sublingually administered buprenorphine. Little improvement was noted after 2 weeks. Six weeks after presentation, a left exenteration was performed and histopathology was consistent with idiopathic sclerosing orbital pseudotumor (ISOP). Ten weeks after presentation, the patient presented for weight loss and jaw pain. Computed tomography demonstrated disease progression in the right orbit and the patient was euthanized. Histopathology of the decalcified skull revealed an aggressive and highly infiltrative mass involving the right orbit with extension to the maxilla, hard palate, nasal cavity and gingiva most consistent with feline restrictive orbital myofibroblastic sarcoma (FROMS). Clinical Relevance Clinical data from this patient support the reclassification of ISOP as FROMS. MRI and CT may provide supportive evidence for FROMS but histopathology is necessary for definitive diagnosis. Aggressive and early surgical treatment, including bilateral exenteration, with adjunctive radiotherapy and/or chemotherapy should be considered for patients with FROMS. PMID:23281709

Bariatric surgery: is it reasonable before the age of 16?

PubMed

Massabki, Lilian Helena Polak; Sewaybricker, Letícia Esposito; Nakamura, Keila Hayashi; Mendes, Roberto Teixeira; Barros, Antonio DE Azevedo; Antonio, Maria Ângela Reis DE Góes Monteiro; Zambon, Mariana Porto

2016-01-01

to assess the severity of obesity in children and adolescents through the presence of comorbidities and the potential indication of bariatric surgery. we conducted a cross-sectional study with clinical and laboratory data of the first consultation of patients at the childhood obesity clinic at a tertiary hospital from 2005 to 2013. We divided the patients into groups with or without potential indication for surgery, and recorded age, gender, birth weight, age of obesity onset, BMI Z score, presence of acanthosis nigricans, blood pressure, total cholesterol and fractions, triglycerides, blood glucose and fasting insulin, HOMA1-IR, CRP and ESR. The group with potential indication for surgery included: BMI > 40 or between 35-40 with comorbidities (Triglycerides >130mg/dl, glucose levels >100mg/dl, HOMA1-IR >3.16, Total Cholesterol >200mg/dl, LDL >130mg/dl and HDL <45mg/dl), regardless of age, epiphysis consolidation and previous treatment. of the 296 patients included in the study, 282 (95.3%) were younger than 16 years. The most frequent change was the HDL (63.2%), followed by HOMA1-IR (37.5%). Of the group of 66 patients with potential indication for surgery (22.3%), only ten (15.1%) had more than 16 years. Acanthosis nigricans, the average HOMA1-IR, insulin, CRP, ESR, age, BMI Z score and systolic and diastolic blood pressure were significant in the group with potential surgical indication. bariatric surgery might be indicated by BMI and comorbidities in children and adolescents under 16 years. avaliar a gravidade da obesidade em crianças e adolescentes pela presença de comorbidades e pela potencial indicação de cirurgia bariátrica. estudo transversal com dados clínicos e laboratoriais da primeira consulta de pacientes do ambulatório de obesidade infantil em um hospital terciário no período de 2005 a 2013. Os pacientes foram divididos em grupos com ou sem potencial indicação cirúrgica, e associados com idade, sexo, peso de nascimento, idade de início da obesidade, escore z de IMC, presença de acantose nigricans, pressão arterial, colesterol total e frações, triglicérides, glicemia e insulina de jejum, HOMA1-IR, PCR e VHS. O grupo com potencial indicação cirúrgica incluiu: IMC >40 ou IMC entre 35-40 com comorbidades (Triglicérides >130mg/dl, Glicemia >100mg/dl, HOMA1-IR >3,16, Colesterol total >200mg/dl, LDL >130mg/dl e HDL <45mg/dl), independente da idade, consolidação das epífises e tratamento prévio. de 296 pacientes incluídos no estudo, 282 (95,3%) tinham menos de 16 anos. A alteração mais frequente foi a do HDL (63,2%), seguido do HOMA1-IR (37,5%). Do grupo de 66 pacientes com potencial indicação cirúrgica (22,3%), apenas dez (15,1%) tinham mais de 16 anos. Acantose nigricans, as médias de HOMA1-IR, insulina, PCR, VHS, idade, escore z de IMC e pressões sistólica e diastólica foram significantes no grupo com potencial indicação cirúrgica. os resultados sugerem que a cirurgia bariátrica, poderia estar indicada pelo IMC e presença de comorbidades, em crianças e adolescentes com menos de 16 anos.

Detailed Field Investigation of Vapor Intrusion Processes

DTIC Science & Technology

2008-08-01

difluoroethane DQO data quality objective ESTCP Environmental Security Technology Certification Program HCl hydrochloric acid OU-5 Operable Unit...impacted by significant leakage of ambient air. Some leak tracer compounds such as difluoroethane (DFA) and isopropyl alcohol may cause elevated detection

Use and Understanding of the Proximate Status Indication in Traffic Displays

DOT National Transportation Integrated Search

2011-10-16

Traffic Collision Avoidance System (TCAS) traffic displays use symbol fill to distinguish proximate from non-proximate targets, where proximate targets are within a specified range and altitude of ownship, and non-proximate targets are ou...

OAS :: Office of the Inspector General

Science.gov Websites

Internal Audit Real Estate Strategy Calendar Calendar of Conferences in Headquarters OAS Logo OAS Logo It este sitio de web. Afigura-se o JavaScript está desativado ou desligado. Por favor ative o JavaScript

Dynamique de nanobulles et nanoplasmas generes autour de nanoparticules plasmoniques irradiees par des impulsions ultracourtes

NASA Astrophysics Data System (ADS)

Dagallier, Adrien

L'emergence des lasers a impulsion ultrabreves et des nanotechnologies a revolutionne notre perception et notre maniere d'interagir avec l'infiniment petit. Les gigantesques intensites generees par ces impulsions plus courtes que les temps de relaxation ou de diffusion du milieu irradie induisent de nombreux phenomenes non-lineaires, du doublement de frequence a l'ablation, dans des volumes de dimension caracteristique de l'ordre de la longueur d'onde du laser. En biologie et en medecine, ces phenomenes sont utilises a des fins d'imagerie multiphotonique ou pour detruire des tissus vivants. L'introduction de nanoparticules plasmoniques, qui concentrent le champ electromagnetique incident dans des regions de dimensions nanometriques, jusqu'a une fraction de la longueur d'onde, amplifie les phenomenes non-lineaires tout en offrant un controle beaucoup plus precis de la deposition d'energie, ouvrant la voie a la detection de molecules individuelles en solution et a la nanochirurgie. La nanochirurgie repose principalement sur la formation d'une bulle de vapeur a proximite d'une membrane cellulaire. Cette bulle de vapeur perce la membrane de maniere irreversible,entrainant la cellule a sa mort, ou la perturbe temporairement, ce qui permet d'envisager de faire penetrer dans la cellule des medicaments ou des brins d'ADN pour de la therapie genique. C'est principalement la taille de la bulle qui va decider de l'issue de l'irradiation laser. Il est donc necessaire de controler finement les parametres du laser et la geometrie de la nanoparticule afin d'atteindre l'objectif fixe. Le moyen le plus direct a l'heure actuelle de valider un ensemble de conditions experimentales est de realiser l'experience en laboratoire,ce qui est long et couteux. Les modeles de dynamique de bulle existants ne prennent pas en compte les parametres de l'irradiation et ajustent souvent leurs conditions initiales a partir de leurs mesures experimentales, ce qui limite la portee du modele au cas pour lequel il est ecrit. Ce memoire se propose de predire la taille maximale ainsi que la dynamique des bulles generees par des impulsions ultrabreves en fonction uniquement de la geometrie de la particule et des parametres du laser, entre autres la duree de pulse, la longueur d'onde centrale et la fluence d'irradiation.

Remedial Investigation Report on Chestnut Ridge Operable Unit 2 (Filled Coal Ash Pond/Upper McCoy Branch) at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee. Volume 1. Main Text

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-08-01

This document is a report on the remedial investigation (RI) of Chestnut Ridge Operable Unit (OU) 2 at the Oak Ridge Y-12 Plant. Chestnut Ridge OU 2 consists of Upper McCoy Branch (UMB), the Filled Coal Ash Pond (FCAP), and the area surrounding the Sluice Channel formerly associated with coal ash disposal in the FCAP. Chestnut Ridge OU 2 is located within the U.S. Department of Energy`s (DOE`s) Oak Ridge Reservation in Anderson County, Tennessee, approximately 24 miles west of Knoxville. The pond is an 8.5-acre area on the southern slope of Chestnut Ridge, 0.5 mile south of the mainmore » Y-12 Plant and geographically separated from the Y-12 Plant by Chestnut Ridge. The elevation of the FCAP is {approximately} 950 ft above mean sea level (msl), and it is relatively flat and largely vegetated. Two small ponds are usually present at the northeast and northwest comers of the FCAP. The Sluice Channel Area extends {approximately}1000 ft from the northern margin of the FCAP to the crest of Chestnut Ridge, which has an elevation of {approximately}1100 ft above msl. The Sluice Channel Area is largely vegetated also. McCoy Branch runs from the top of Chestnut Ridge across the FCAP into Rogers Quarry and out of the quarry where it runs a short distance into Milton Hill Lake at McCoy Embayment, termed UMB. The portion south of Rogers Quarry, within Chestnut Ridge OU 4, is termed Lower McCoy Branch. The DOE Oak Ridge Y-12 Plant disposed of coal ash from its steam plant operations as a slurry that was discharged into an ash retention impoundment; this impoundment is the FCAP. The FCAP was built in 1955 to serve as a settling basin after coal ash slurried over Chestnut Ridge from the Y-12 Plant. The FCAP was constructed by building an earthen dam across the northern tributary of McCoy Branch. The dam was designed to hold 20 years of Y-12 steam plant ash. By July 1967, ash had filled up the impoundment storage behind the dam to within 4 ft of the top.« less

Middlesex FUSRAP Site - A Path to Site-Wide Closure - 13416

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, David M.; Edge, Helen

2013-07-01

The road-map to obtaining closure of the Middlesex Sampling Plant FUSRAP site in Middlesex, New Jersey (NJ) has required a multi-faceted approach, following the CERCLA Process. Since 1998, the US ACE, ECC, and other contractors have completed much of the work required for regulatory acceptance of site closure with unrestricted use. To date, three buildings have been decontaminated, demolished, and disposed of. Two interim storage piles have been removed and disposed of, followed by the additional removal and disposal of over 87,000 tons of radiologically and chemically-impacted subsurface soils by the summer of 2008. The US ACE received a determinationmore » from the EPA for the soils Operable Unit, (OU)-1, in September 2010 that the remedial excavations were acceptable, and meet the criteria for unrestricted use as required by the 2004 Record of Decision (ROD) for OU-1. Following the completion of OU-1, the project delivery team performed additional field investigation of the final Operable Unit for Middlesex, OU-2, Groundwater. As of December 2012, the project delivery team has completed a Supplemental Remedial Investigation, which will be followed with a streamlined Feasibility Study, Proposed Plan, and ROD. Several years of historical groundwater data was available from previous investigations and the FUSRAP Environmental Surveillance Program. Historical data indicated sporadic detections of Volatile Organic Compounds (VOCs), primarily trichloroethylene (TCE), carbon tetrachloride (CT), and methyl tert-butyl ether (MTBE), with no apparent trend or pattern indicating extent or source of the VOC impact. In 2008, the project delivery team initiated efforts to re-assess the Conceptual Site Model (CSM) for groundwater. The bedrock was re-evaluated as a leaky multi-unit aquifer, and a plan was developed for additional investigations for adequate bedrock characterization and delineation of groundwater contaminated primarily by CT, TCE, and tetrachloroethene (PCE). The investigation was designed to accumulate multiple lines of evidence to determine the source and to delineate the extent of contamination, as required to complete the CERCLA Process and gain regulatory acceptance. Investigative techniques included in-well vertical flow tracing, borehole geophysics and packer testing of temporary test holes to characterize contamination in the bedrock fractures beneath the site, and to delineate likely source areas. (authors)« less

Remediation System Evaluation, Comm. Bay/South Tacoma Channel, Well 12A Superfund Site

EPA Pesticide Factsheets

The first operable unit (OU1) of the Commencement Bay/South Tacoma Channel Superfund Site addressessoil and groundwater contamination associated with the Time Oil property that was first discovered inpublic supply Well 12A in 1981.

78 FR 29499 - Proposed Priorities, Requirements, Definitions, and Selection Criteria-Race to the Top-Early...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-20

... social development. Teachers College Record, 112(3), 579-620. \\5\\ Reynolds, A.J., Temple, J.A., Ou, S... and family engagement, including in the early grades; (d) Increasing the percentage of children who...

Graduate student recruiting into critical transportation infrastructure areas of interest.

DOT National Transportation Integrated Search

2013-01-01

This report presents the results of a three-year, intensive recruiting and mentoring program in : the University of Oklahomas (OU) College of Engineering (CoE). Highly qualified and diverse : graduate students were sought to pursue degrees in tran...

Hollow-core FRP-concrete-steel bridge columns under extreme loading.

DOT National Transportation Integrated Search

2015-04-01

This report presents the behavior of hollow-core fiber reinforced polymer concrete - steel columns (HC-FCS) under : combined axial-flexural as well as vehicle collision loads. The HC-FCS column consists of a concrete wall sandwiched between an ou...

DIAMOND ALKALI OU2 - PASSAIC RIVER STUDY AREA

EPA Science Inventory

EPA, the U.S. Army Corps of Engineers (Corps), New Jersey Department of Transportation (NJDOT) ), National Oceanic and Atmospheric Administration (NOAA), U.S. Fish and Wildlife Service (USFWS) and New Jersey Department of Environmental Protection (NJDEP) are conducting a joint st...

Review of Non-Chemical Stressors from the Social Environment

EPA Science Inventory

Non-chemical stressors (e.g., noise, diet, temperature, overcrowding) are found in the built, natural and social environments. Correlations between exposure to non-chemical stressors in the social environment (e.g., SES, exposure to violence, acculturation) and negative health ou...

Chlorophylls, proteins and fatty acids amounts of arthrospira platensis growing under saline conditions.

PubMed

Ayachi, Samah; El Abed, Amor; Dhifi, Wissal; Marzouk, Brahim

2007-07-15

Spirulina platensis (Arthrospira platensis) is a Tunisian strain isolated for the first time, in Tunisia, in Oued Essed (Sidi Bou Ali, in Sousse region). Evolution of biomass, proteins, chlorophylls and fatty acids (FA) has been followed during Spirulina growth. Experiments were carried out by varying sodium chloride concentrations in the culture medium in a range from 1 g L(-1) (natural environment) to 60 g L(-1). Results analysis showed an increase in chlorophyll amounts at 15 g L(-1) NaCl in 10 days old cultures but a decrease at high NaCl concentrations. Optimal proteins amounts was observed at 15 g L(-1) NaCl in young cultures (5 and 10 days). FA composition was modified by NaCl and depended on culture age. Cultures exposed to high salinity concentrations showed not only a decrease in growth rate but also a loss in total fatty acids TFA quantities. Samples cultured over 15 days at 30 g L(-1) NaCl rendered optimal quantities of lipids and gamma-linolenic acid.

Odour emission characteristics of 22 recreational rivers in Nanjing.

PubMed

Wan, Yu; Ruan, Xiaohong; Wang, Xinguang; Ma, Qian; Lu, Xiaoming

2014-10-01

The odour emission characteristics of 22 recreational rivers in Nanjing were investigated and analysed. Eight odorous compounds (ammonia (NH₃), hydrogen sulphide (H₂S), sulphur dioxide (SO₂), carbon disulphide (CS₂), nitrobenzene (C₆H₅NO₂), aniline (C₆H₅NH₂), dimethylamine (C₂H₇N), and formaldehyde (HCHO)) were measured in odour emission samples collected using a custom-made emission flux hood chamber. The results showed that all odorants were detected in all monitoring rivers. NH₃ was the main odorant, with emission rates ranging from 4.86 to 15.13 μg/min m(2). The total odour emission rate of the Nan River, at 1 427.07 OU/s, was the highest of the all investigated rivers. H₂S, NH₃ and nitrobenzene were three key odour emission contributors according to their contributions to the total odour emission. A correlation analysis of the pollutants showed there was a significant positive correlation between the emission rate of NH₃ and the concentration of ammonia nitrogen (NH₄ (+)-N) and total nitrogen (TN). The H₂S and SO₂ emission rates had a significant positive correlation with sulphides (S(2-)) and available sulphur (AS) in the water and sediment. The content of TN, NH₄(+)-N, S(2-) and AS in the water and sediment affected the concentration of H₂S, SO₂ and NH₃ in the emission gases. NH₄(+)-N, S(2-) and AS are suggested as the key odour control indexes for reducing odours emitted from these recreational rivers. The study provides useful information for effective pollution control, especially for odour emission control for the recreational rivers of the city. It also provides a demonstrate example to show how to monitor and assess a contaminated river when odour emission and its control need to be focused on.

Utility of Ultraportable Echocardiography in the Preoperative Evaluation of Noncardiac Surgery.

PubMed

Costa, Jean Allan; Almeida, Maria Lucia Pereira; Estrada, Tereza Cristina Duque; Werneck, Guilherme Lobosco; Rocha, Alexandre Marins; Rosa, Maria Luiza Garcia; Ribeiro, Mario Luiz; Mesquita, Claudio Tinoco

2016-11-01

The ultraportable echocardiogram machine, with relevant portability and easiness in performing diagnoses, when in experienced hands, may contribute to the reliability of preoperative evaluation in noncardiac surgeries. To assess cardiac function parameters in patients aged older than 60 years, candidates of elective noncardiac surgeries, classified as ASA1 or ASA 2 according to surgical risk. A total of 211 patients referred for elective surgeries, without suspicion of previous heart diseases, were included in the study. Assessment of patients was conducted by conventional echocardiogram using the ultraportable V Scan (GE) device right after the pre-anesthetic clinical evaluation. We assessed the clinical impact of echocardiography results by using a questionnaire addressed to the anesthetist. Mean age of patients was 68.9 ± 7.0 years, 154 were women. The most frequent surgeries were: a) facectomy - cataract - 18; b) inguinal hernia surgery - 18; c) Cholecystectomy - 16. We found 58 normal tests (27.5%), 70 (33.2%) with mild valve reflux, and 83 (39.3%) with relevant abnormality, such as increase in heart chamber size, global and/or segmental contractile dysfunction, significant valve dysfunction or other unspecified. Test results caused delay of surgical procedure for a more detailed cardiac evaluation in 20 (9.5%) patients, and change in anesthetic management in 7 (3.3%). There was a considerable clinical impact with the use of the ultraportable echocardiography, since one out of every ten patients evaluated had their clinical management changed due to the detection of previously unsuspected, significant heart diseases, with the potential for severe complications. O ecocardiógrafo ultraportátil, com importante mobilidade e facilidade diagnóstica em mãos experientes pode contribuir para a segurança na avaliação pré-operatória em cirurgias não cardíacas. Avaliar os parâmetros de função cardíaca nos pacientes com mais de 60 anos de idade, candidatos a cirurgias não-cardíacas eletivas, classificados como ASA 1 ou ASA 2 na classificação de risco cirúrgico. Foram incluídos 211 pacientes direcionados para cirurgias eletivas diversas e sem suspeita prévia de cardiopatia. Os pacientes foram avaliados por técnica ecocardiográfica convencional, usando o aparelho ultraportátil V Scan (GE) logo após a avaliação clínica pré-anestésica. Avaliamos o impacto clínico dos resultados da ecocardiografia por um questionário dirigido ao anestesista. A idade média dos pacientes foi 68,9 ± 7,0 anos, 154 do sexo feminino. As cirurgias mais frequentes foram: a) Facectomia-catarata - 18; b) Herniorrafia inguinal - 18; c) Colecistectomia - 16. No total, foram observados 58 exames normais (27,5%), 70 (33,2%) exames que apresentavam leves refluxos valvares e 83 (39,3%) exames com alguma anormalidade relevante, como aumento de câmara cardíaca, disfunção contrátil global e/ou segmentar, disfunção valvar mais significativa ou outra não especificada. Os resultados determinaram que 20 (9,5%) pacientes tivessem seus procedimentos cirúrgicos adiados até avaliação cardiológica mais detalhada e em 7 (3,3%) houve mudança na conduta anestésica. Houve um impacto clínico considerável com o uso da ecocardiografia ultraportátil, pois um em cada dez pacientes avaliados sofreu modificação na conduta clínica, em função da detecção de cardiopatias significativas, não suspeitadas previamente, e com potencial para complicações graves.

Discordance gradient-surface dans le rétrécissement mitral: le gradient moyen transmitral est-il un critère de sévérité ou un indice de tolérance du rétrécissement mitral serré?

PubMed Central

Najih, Hayat; Arous, Salim; Laarje, Aziza; Baghdadi, Dalila; Benouna, Mohamed Ghali; Azzouzi, Leila; Habbal, Rachida

2016-01-01

Le rétrécissement mitral (RM) rhumatismal demeure une valvulopathie fréquente dans les pays en voie de développement. Cependant, les pays industrialisés ont vu l'émergence ces dernières années de nouvelles étiologies de RM; notamment l'origine médicamenteuse et/ou toxique responsable de valvulopathies restrictives aussi bien sténosantes que régurgitantes. Pour cette raison, l'évaluation échocardiographique du RM et surtout, la définition de critères objectifs pour conclure au caractère serré du RM reste toujours d'actualité. Les objectifs du travail sont: évaluer l'existence ou non d'une corrélation directe entre le gradient moyen transmitral (GMT) et la sévérité du RM chez les patients porteurs d'un RM serré ou très serré (critère primaire) et analyser les différents paramètres qui conditionnent le gradient moyen transmitral (GMT) (Critère secondaire). Il s'agit d'une étude transversale monocentrique incluant tous les patients admis au service de Cardiologie du CHU Ibn Rochd de Casablanca pour un RM serré ou très serré, sur une période d'une année (Janvier 2014 à Décembre 2014). Nous avons analysés séparément deux groupes de patients : ceux avec un gradient moyen transmitral<10 mmHg (groupe 1) et ceux avec un gradient>10mmHg (groupe2). 50 patients porteurs d'un RM serré ou très serré ont été inclus. L'âge moyen de nos patients est de 41,7 ans avec prédominance féminine (sex ratio: 0,25). 64% de nos patients avaient un RM serré et 36% avaient un RM très serré. 52% (26 patients) avaient un GMT <10mmHg et 48% (24 patients) avaient un gradient moyen >10mmHg, ce qui suggère l'absence de corrélation directe entre la sévérité du RM et le GMT (coefficient de Pearson R: -0,137). Pour la dyspnée, 80% des patients du groupe 1 étaient dyspnéiques stade II de la NYHA et 70% des patients du groupe 2 étaient dyspnéiques stade III (41%) ou IV (29%) de la NYHA, ce qui signifie l'existence d'une corrélation significative entre le GMT et la sévérité de la dyspnée (R: 0,586 et p: 0,001). L'étude analytique de la fréquence cardiaque et la présence d'une décompensation cardiaque par rapport au gradient moyen transmitral a montré une corrélation significative. En effet, parmi les patients du groupe 1, 96% avaient une FC entre 60 et 100 bpm et aucun patient n'était en décompensation cardiaque. Dans le groupe 2,54% (13 patients) avaient une FC >100 bpm et 7 parmi eux (53%) étaient en décompensation cardiaque gauche. L'étude de la pression artérielle pulmonaire systolique dans les deux groupes de l'étude a révélé l'existence dans notre série d'une corrélation statistiquement significative (R : 0,518 et P : 0,001) entre la PAPS et le GMT. La régularité du rythme et la fonction ventriculaire droite n'étaient pas corrélées au GMT (R : 0,038 et R :-0,002 respectivement). Le gradient moyen transmitral est un bon indicateur de la tolérance du rétrécissement mitral, mais il reflète imparfaitement sa sévérité vue qu'il dépend de plusieurs paramètres hémodynamiques. D'authentiques rétrécissements mitraux très serrés peuvent exister avec des gradients moyens transmitraux <10 mm Hg, c'est pour cette raison que la valeur du GMT ne doit jamais être interprétée isolément. PMID:28292038

Socioeconomic and regional differences in active transportation in Brazil.

PubMed

Sá, Thiago Hérick de; Pereira, Rafael Henrique Moraes; Duran, Ana Clara; Monteiro, Carlos Augusto

2016-06-27

To present national estimates regarding walking or cycling for commuting in Brazil and in 10 metropolitan regions. By using data from the Health section of 2008's Pesquisa Nacional por Amostra de Domicílio (Brazil's National Household Sample Survey), we estimated how often employed people walk or cycle to work, disaggregating our results by sex, age range, education level, household monthly income per capita, urban or rural address, metropolitan regions, and macro-regions in Brazil. Furthermore, we estimated the distribution of this same frequency according to quintiles of household monthly income per capita in each metropolitan region of the country. A third of the employed men and women walk or cycle from home to work in Brazil. For both sexes, this share decreases as income and education levels rise, and it is higher among younger individuals, especially among those living in rural areas and in the Northeast region of the country. Depending on the metropolitan region, the practice of active transportation is two to five times more frequent among low-income individuals than among high-income individuals. Walking or cycling to work in Brazil is most frequent among low-income individuals and the ones living in less economically developed areas. Active transportation evaluation in Brazil provides important information for public health and urban mobility policy-making. Apresentar estimativas nacionais sobre o deslocamento a pé ou de bicicleta no trajeto casa-trabalho no Brasil e em 10 de suas regiões metropolitanas. Utilizando dados do Suplemento sobre Saúde da Pesquisa Nacional por Amostra de Domicílios de 2008, estimamos a frequência de pessoas empregadas que se deslocam a pé ou de bicicleta no trajeto casa-trabalho estratificada por sexo, e segundo faixa etária, escolaridade, renda domiciliar per capita, residência em área urbana ou rural, regiões metropolitanas e macrorregiões do país. Adicionalmente, estimamos a distribuição da mesma frequência segundo quintos da distribuição da renda domiciliar per capita em cada região metropolitana. Um terço dos homens e mulheres empregados desloca-se a pé ou de bicicleta de casa para o trabalho no Brasil. Em ambos os sexos, esta proporção diminui com o aumento da renda e da escolaridade e é maior entre os mais jovens, entre os que residem em área rural e naqueles residentes na região Nordeste. A depender da região metropolitana, a prática de deslocamento ativo entre os mais pobres é de duas a cinco vezes maior do que entre os mais ricos. O deslocamento a pé ou de bicicleta para o trabalho no Brasil é mais frequente entre os mais pobres e entre pessoas que vivem em áreas e regiões economicamente menos desenvolvidas. A avaliação do deslocamento ativo no País traz informações importantes para a discussão de políticas públicas de mobilidade.

Optimization Review: Lockwood Operable Unit 1 - Beall Source Area, Billings, Montana

EPA Pesticide Factsheets

The Lockwood Solvent Groundwater Plume Site (LSGPS) consists of two operable units (OUs) and is located on the outskirts of Billings, Montana in EPA Region 8. OU1 consists of contaminated soils and a chlorinated solvent groundwater plume associated with...

L'astronomie dans le monde

NASA Astrophysics Data System (ADS)

Manfroid, J.

2017-05-01

matière sombre – Abell 2744 vu par ALMA – Bousculade dans Orion – Rotation stellaire – Tsunamis martiens – Planète X ou 9 – Formation d’étoiles dans les jets de trous noirs – Éjection d’un trou noir

Determination of interaction between bridge concrete approach slab and embankment settlement.

DOT National Transportation Integrated Search

2005-07-01

The main objective of this research is to correlate the deformation and internal force of the approach slab with the approach embankment settlements and the approach slab parameters such as length and thickness. Finite element analysis was carried ou...

L'astronomie dans le monde

NASA Astrophysics Data System (ADS)

Manfroid, J.

2009-06-01

L'ESA en route vers les origines de l'univers; Record de distance; Blob primordial; Novae; Expansion de l'univers; Plat ou pas?; L'eau sur Mars; Bombardement massif; M87; CoRoT; EX Lupi; Première pour ALMA; Kohoutek 4-55; Arp 194

A decision support system for transportation infrastructure and supply chain system planning.

DOT National Transportation Integrated Search

2013-07-01

This project makes the results (models and methodology) of the research and development efforts on freight movement modeling (FMM) and supply chain design carried out by faculty at OSU and OU available to transportation and logistics professionals. A...

Scout 2008 Version 1.0 User Guide

EPA Science Inventory

The Scout 2008 version 1.0 software package provides a wide variety of classical and robust statistical methods that are not typically available in other commercial software packages. A major part of Scout deals with classical, robust, and resistant univariate and multivariate ou...

Studying the evolutionary significance of thermal adaptation in ectotherms: The diversification of amphibians' energetics.

PubMed

Nespolo, Roberto F; Figueroa, Julio; Solano-Iguaran, Jaiber J

2017-08-01

A fundamental problem in evolutionary biology is the understanding of the factors that promote or constrain adaptive evolution, and assessing the role of natural selection in this process. Here, comparative phylogenetics, that is, using phylogenetic information and traits to infer evolutionary processes has been a major paradigm . In this study, we discuss Ornstein-Uhlenbeck models (OU) in the context of thermal adaptation in ectotherms. We specifically applied this approach to study amphibians's evolution and energy metabolism. It has been hypothesized that amphibians exploit adaptive zones characterized by low energy expenditure, which generate specific predictions in terms of the patterns of diversification in standard metabolic rate (SMR). We complied whole-animal metabolic rates for 122 species of amphibians, and adjusted several models of diversification. According to the adaptive zone hypothesis, we expected: (1) to find "accelerated evolution" in SMR (i.e., diversification above Brownian Motion expectations, BM), (2) that a model assuming evolutionary optima (i.e., an OU model) fits better than a white-noise model and (3) that a model assuming multiple optima (according to the three amphibians's orders) fits better than a model assuming a single optimum. As predicted, we found that the diversification of SMR occurred most of the time, above BM expectations. Also, we found that a model assuming an optimum explained the data in a better way than a white-noise model. However, we did not find evidence that an OU model with multiple optima fits the data better, suggesting a single optimum in SMR for Anura, Caudata and Gymnophiona. These results show how comparative phylogenetics could be applied for testing adaptive hypotheses regarding history and physiological performance in ectotherms. Copyright © 2016 Elsevier Ltd. All rights reserved.

Remedial investigation/feasibility study for the Clinch River/Poplar Creek operable unit. Volume 1. Main text

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-09-01

This is the combined Remedial Investigation/Feasibility Study Report for the Clinch River/Poplar Crack (CR/PC) Operable Unit (OU). The CR/PC OU is located in Anderson and Roane Counties, Tennessee and consists of the Clinch River and several of its embayments in Melton Hill and Watts Bar Reservoirs. These waters have received hazardous substances released over a period of 50 years from the US Department of Energy`s Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensive Environmental Response, Compensation, and Liability Act. A remedial investigation has been conducted to determine the current nature and extent of any contaminationmore » and to assess the resulting risk to human health and the environment. The feasibility study evaluates remedial action alternatives to identify any that are feasible for implementation and that would effectively reduce risk. Historical studies had indicated that current problems would likely include {sup 137}Cs in sediment of the Clinch River, mercury in sediment and fish of Poplar Creek and PCBs and pesticides in fish from throughout the OU. Peak releases of mercury and {sup 137}Cs occurred over 35 years ago, and current releases are low. Past releases of PCBs from the ORR are poorly quantified, and current releases are difficult to quantify because levels are so low. The site characterization focused on contaminants in surface water, sediment, and biota. Contaminants in surface water were all found to be below Ambient Water Quality Criteria. Other findings included the following: elevated metals including cesium 137 and mercury in McCoy Branch sediments; PCBs and chlordane elevated in several fish species, presenting the only major human health risk, significant ecological risks in Poplar Creek but not in the Clinch River.« less

[Different responses of growth and root development of Schima superba provenance to the adjacent plant competition in different nutrient conditions].

PubMed

Yao, Jia Bao; Chu, Xiu Li; Zhou, Zhi Chun; Tong, Jian She; Wang, Hui; Yu, Jia Zhong

2017-04-18

Growth and root development of three Schima superba seedling provenances were influenced by adjacent plant competition in the homogeneous and heterogeneous nutrient environment, which revealed the reasons of S. superba competition differences in the different genotypes. The results indicated that, compared with homogeneous nutrient environment, all three S. superba provenances showed higher seedling height, more dry matter accumulation, and significant root proliferation in heterogeneous nutrient environment. Under heterogeneous nutrient environment, the seedlings of S. superba from Jian'ou of Fujian exhibited higher competitive advantage in growth than that of S. superba from Longquan of Zhejiang and Xinfeng of Jiangxi, especially standing out under mixed cultivation with seedlings of Cunninghamia lanceolata. Under mixed cultivation, the root growth parameters of S. superba such as root length, root surface area and volume increased by 20.4%-69.0% compared with the single plant, which enhanced the foraging ability and growth advantage. To some extent, however, the root development in Longquan of Zhejiang and Xinfeng of Jiangxi was suppressed when subjected to the pattern of mixed cultivation. Besides, the root growth and development of all three S. superba provenances were suppressed, which might be due to their root self-recognition in the pattern of mono cultivation. Therefore, the seedling growth in Jian'ou of Fujian decreased significantly, but seedling growth in Longquan of Zhejiang and Xinfeng of Jiangxi was not suppressed, even increased evidently, as their root physiological plasticity might play the crucial role in seedling growth. Hence the S. superba from Jian'ou of Fujian with high foraging efficiency and competition ability was suggested with the method of mixed forestation to improve the S. superba forest plantation productivity.

Tuberculose pelvi-péritoneale pseudotumorale: à propos de quatre cas

PubMed Central

Saadi, Hanane; Mamouni, Nissrine; Errarhay, Sanaa; Bouchikhi, Chahrazed; Banani, Abdelaziz; Ammor, Hicham; Sqalli, Nadia; Tizniti, Siham; Benmajdoube, Karim; Maazaze, Khalid; Fatmi, Hind; Amarti, Afaf

2012-01-01

La tuberculose pelvienne pseudo tumorale est une maladie infectieuse curable. Son tableau clinique est souvent trompeur simulant une tumeur ovarienne ou tubaire. Le but de notre travail est de préciser les caractéristiques cliniques, biologiques et radiologiques de cette pathologie et sa prise en charge. Nous rapportons une étude rétrospective à propos de quatre observations. L’âge moyen de nos patientes est de 24 ans (16 ans, 40 ans), trois parmi elles étaient célibataires. Le motif de consultation est dominé par les douleurs abdominopelviennes chroniques. Les résultats des explorations radiologiques (échographie pelvienne associé à la TDM ou IRM pelvienne) ont été en faveur d'une tumeur ovarienne dans trois cas et d'un hydrosapinx bilatéral pour un cas. L'ascite a été présente dans tous les cas. Le dosage de la Ca 125 a été élevé. La prise en charge a été l'exploration chirurgicale soit par c'lioscopie ou laparotomie. Deux cas ont bénéficié seulement des biopsies et deux patientes ont eu une salpingectomie bilatérale devant l'aspect pseudo tumoral très suspect. L’étude histologique a confirmé des lésions graulomateuses avec nécrose caséeuse. Le traitement par les antibacillaires a été instauré selon le protocole 2ERHZ/ 4RH. La tuberculose pelvienne pseudo tumorale est l'apanage de la femme jeune. Son pronostic est lié à l'infertilité séquellaire. PMID:23330043

L'endométriose de la paroi abdominale: à propos d'un cas rare

PubMed Central

Jayi, Sofia; Laadioui, Meriem; Bouguern, Hakima; Chaara, Hikmat; Melhouf, Aabdelilah

2013-01-01

L'endométriose de la paroi est une entité clinique rare, dont la physiopathologie demeure imprécise. Elle survient le plus souvent après une intervention chirurgicale gynécologique ou obstétricale. Nous rapportons le cas d'une patiente présentant une douleur cyclique, au niveau de la cicatrice de césarienne. Avec à l'examen clinique une masse de 3 cm localisée au niveau de la fosse iliaque droite. L'échographie-doppler a objectivé une image d'allure tissulaire, polylobée, à vascularisation centrale, mesurant 32/16 mm, évoquent une masse endométriosique ou une tumeur des parties molles. D'où la décision d'excision de la lésion, au cours de laquelle on a découvert une masse dure de 3/2 cm, en sous aponévrotique accolée au muscle grand droit de l'abdomen. L'étude anatomopathologique a confirmé le diagnostic d'endométriose pariétale. Les suites postopératoires étaient simples avec un recul de 2 ans et demie sans récidive de la masse ni de la douleur. A travers notre cas, nous insisterons sur les caractéristiques de cette pathologie notamment pronostic, ce qui permettra au praticien de comprendre l'intérêt du diagnostic et prise en charge précoce de cette entité - pour laquelle on ne pense jamais assez devant une masse pariétale - et de sa prévention au cours de chaque chirurgie gynécologique ou obstétricale. PMID:24171068

Evolution des quasiparticules nodales du cuprate supraconducteur YBa2Cu3Oy en conductivite thermique

NASA Astrophysics Data System (ADS)

Rene de Cotret, Samuel

Ce memoire presente des mesures de conductivite thermique sur les supraconducteurs YBCO et Tl-2201 afin de statuer sur la presence possible d'un point critique quantique (QCP) dans le diagramme de phase de cuprates. Ce point critique quantique serait a l'origine de la reconstruction de la surface de Fermi, d'un large cylindre de trous en de petites poches de trous et d'electrons. La conductivite thermique dans le regime T → 0 permet d'extraire une quantite purement electronique liee aux vitesses de Fermi et du gap, au noeud. Une discontinuite dans cette quantite pourrait signaler la traversee du dopage critique qui reconstruit la surface de Fermi. Plusieurs sondes experimentales distinguent une transition de phase ou un crossover a T* a temperature finie. D'autres sondes mettent en evidence une transition de phase sous l'effet d'un champ magnetique. La presence ou non de cet ordre, a temperature et champ magnetique nul questionne la communaute depuis plusieurs annees. Dans cette etude, nous detectons une variation brusque de kappa0/T a p = 0.18 dans YBCO et a p = 0.20 dans Tl-2201. Ces sauts sont interpretes comme un signe de la transition a temperature nulle et sont en faveur d'un QCP. Le manque de donnees d'un meme materiau a ces dopages ne permet pas de valider hors de tout doute l'existence d'un point critique quantique. Le modele theorique YRZ decrit aussi bien les donnees de conductivite thermique. Des pistes de travaux experimentaux a poursuivre sont proposees pour determiner la presence ou non du QCP de facon franche. Mots-cles : Supraconducteurs, cuprates, conductivite thermique, point critique quantique.

Profilaxia da trombose venosa profunda em cirurgia bariátrica: estudo comparativo com doses diferentes de heparina de baixo peso molecular

PubMed Central

Goslan, Carlos José; Baretta, Giórgio Alfredo Pedroso; de Souza, Hemuara Grasiela Pestana; Orsi, Bruna Zanin; Zanoni, Esdras Camargo A.; Lopes, Marco Antonio Gimenez; Engelhorn, Carlos Alberto

2018-01-01

Resumo Contexto A cirurgia bariátrica é considerada a melhor opção para o tratamento da obesidade, cujos pacientes são considerados de alto risco para fenômenos tromboembólicos. Objetivos Comparar o uso de doses diferentes de heparina de baixo peso molecular (HBPM) na profilaxia da trombose venosa profunda (TVP) em pacientes candidatos à cirurgia bariátrica em relação ao risco de TVP, alteração na dosagem do fator anti-Xa e sangramento pré ou pós-operatório. Métodos Estudo comparativo transversal em pacientes submetidos à cirurgia bariátrica distribuídos em dois grupos, que receberam doses de HBPM de 40 mg (grupo controle, GC) e 80 mg (grupo de estudo, GE). Foram avaliados por ultrassonografia vascular e dosagem de KPTT, TAP, plaquetas e fator anti-Xa. Resultados Foram avaliados 60 pacientes, sendo 34 no GC e 26 no GE. Foi observada diferença significativa somente no peso (p = 0,003) e índice de massa corporal (p = 0,018) no GE em relação ao GC. Não houve diferença na dosagem de KPTT, TAP, plaquetas e fator anti-Xa entre os grupos. Não foram detectados TVP ou sangramentos significativos em ambos os grupos. Conclusões Não houve diferença estatisticamente significativa na utilização de doses maiores de HBPM na profilaxia da TVP em pacientes candidatos à cirurgia bariátrica em relação ao risco de TVP, dosagem do fator anti-Xa e sangramento pré ou pós-operatório.

Contribution to the study of pollution of soil and water in Oued El Maleh area (Mohammedia, Morocco)

NASA Astrophysics Data System (ADS)

El hajjaji, Souad; Dahchour, Abdelmalek; Belhsaien, Kamal; Zouahri, Abdelmjid; Moussadek, Rachid; Douaik, Ahmed

2016-04-01

In Morocco, diffuse ground and surface water pollution in irrigated areas has caused an increase in the risk of water and soil quality deterioration. This has generated a health and environmental risks. The present study was carried out in the Oued El Maleh region located 65 Km to the south of Rabat on the Moroccan Atlantic coast. It covers a surface area of 310 km2 where agriculture constitutes the main activity of the population. This region is considered as a very important agricultural area, known nationally for its high potential for market gardening. This intensification has been accompanied by an excessive use of agrochemical inputs and poor control of irrigation and drainage. Consequently, salinization phenomena and deterioration of soil structure as well as water are about to create an alarming situation. In order to assess the state of pollution of waters and soil in the region, our study focuses on the determination of physicochemical parameters for the quality of water and soil. The obtained results from sampled wells and surface water show relatively higher values of nitrate and conductivity exceeding Moroccan national standards and revealing net degradation of water quality; therefore the water can be considered not suitable for human consumption and can induce a degradation of soil. The results of the studied soil show that the pH of these soils is weakly to moderately basic; they are usually non-saline with organic matter content moderately filled. Moreover, very high concentrations of nutrients (potassium, phosphorus and nitrogen) were recorded, highlighting poor management fertilizing vegetable crops in the region of Oued El Maleh.

Modelisation par elements finis du muscle strie

NASA Astrophysics Data System (ADS)

Leonard, Mathieu

Ce present projet de recherche a permis. de creer un modele par elements finis du muscle strie humain dans le but d'etudier les mecanismes engendrant les lesions musculaires traumatiques. Ce modele constitue une plate-forme numerique capable de discerner l'influence des proprietes mecaniques des fascias et de la cellule musculaire sur le comportement dynamique du muscle lors d'une contraction excentrique, notamment le module de Young et le module de cisaillement de la couche de tissu conjonctif, l'orientation des fibres de collagene de cette membrane et le coefficient de poisson du muscle. La caracterisation experimentale in vitro de ces parametres pour des vitesses de deformation elevees a partir de muscles stries humains actifs est essentielle pour l'etude de lesions musculaires traumatiques. Le modele numerique developpe est capable de modeliser la contraction musculaire comme une transition de phase de la cellule musculaire par un changement de raideur et de volume a l'aide des lois de comportement de materiau predefinies dans le logiciel LS-DYNA (v971, Livermore Software Technology Corporation, Livermore, CA, USA). Le present projet de recherche introduit donc un phenomene physiologique qui pourrait expliquer des blessures musculaires courantes (crampes, courbatures, claquages, etc.), mais aussi des maladies ou desordres touchant le tissu conjonctif comme les collagenoses et la dystrophie musculaire. La predominance de blessures musculaires lors de contractions excentriques est egalement exposee. Le modele developpe dans ce projet de recherche met ainsi a l'avant-scene le concept de transition de phase ouvrant la porte au developpement de nouvelles technologies pour l'activation musculaire chez les personnes atteintes de paraplegie ou de muscles artificiels compacts pour l'elaboration de protheses ou d'exosquelettes. Mots-cles Muscle strie, lesion musculaire, fascia, contraction excentrique, modele par elements finis, transition de phase

Effect of Combination Therapy with Neuroprotective and Vasoprotective Agents on Cerebral Ischemia.

PubMed

Yang, Jiping; Yang, Bei; Xiu, Baoxin; Qi, Jinchong; Liu, Huaijun

2018-05-01

Because most tested drugs are active against only one of the damaging processes associated with stroke, other mechanisms may cause cellular death. Thus, a combination of protective agents targeting different pathophysiological mechanisms may obtain better effects than a single agent. The major objective of this study was to investigate the effect of combination therapy with vascular endothelial growth factor (VEGF) and nerve growth factor (NGF) after controlled ischemic brain injury in rabbits. Animals were randomly assigned to one of the following groups: sham group, saline-treated control group or NGF+VEGF-treated group. Animals received an intracerebral microinjection of VEGF and NGF or saline at 5 or 8 hours after ischemia. The two specified time points of administration were greater than or equal to the existing therapeutic time window for monoterapy with VEGF or NGF alone (3 or 5 hours of ischemia). Infarct volume, water content, neurological deficits, neural cell apoptosis and the expression of caspase-3 and Bcl-2 were measured. Compared with saline-treated controls, the combination therapy of VEGF and NGF significantly reduced infarct volume, water content, neural cell apoptosis and the expression of caspase-3, up-regulated the expression of Bcl-2 and improved functional recovery (both p<0.01) when administered 5 or 8 hours after ischemia. The earlier the administration the better the neuroprotection. These results showed that the combination therapy with VEGF and NGF provided neuroprotective effects. In addition, the time window of combination treatment should be at least 8 hours after ischemia, which was wider than monotherapy. RÉSUMÉ: Les effets d'une polythérapie combinant agents neuro-protecteurs et agents vasoprotecteurs dans les cas d'ischémie cérébrale. Contexte:Étant donné que la plupart des médicaments préalablement testés tendent à n'agir contre seulement un des processus de dommage associés aux AVC, il est possible que d'autres processus entraînent une mort cellulaire. À cet effet, il se pourrait qu'une combinaison d'agents protecteurs ciblant divers mécanismes physiopathologiques permette d'obtenir de meilleurs résultats qu'un simple agent. Après avoir suscité de façon contrôlée des lésions cérébrales ischémiques chez des lapins, l'objectif principal de la présente étude a donc été de se pencher sur l'impact d'une polythérapie combinant la protéine dite « facteur de croissance de l'endothélium vasculaire » (ou « VEGF » en anglais) avec le « facteur de croissance des nerfs » (ou « NGF » en anglais). Méthodes: Les animaux ont été attribués au hasard à l'un des groupes suivants : ceux ayant reçu un traitement fictif ; ceux, du groupe témoin, ayant bénéficié d'un traitement à base de solution saline ; et finalement ceux ayant été traités au moyen des VEGF et NGF. À noter que les lapins ont reçu une micro-injection intracérébrale de VEGF et de NGF ou de solution saline 5 heures ou 8 heures à la suite de leur AVC. Ces deux délais d'administration des VEGF et NGF sont équivalents ou supérieurs aux délais actuels d'administration des VEGF ou NGF à titre de monothérapie (3 heures ou 5 heures à la suite d'un AVC). Tant le volume des infarctus, le contenu en eau, les déficits neurologiques ainsi causés, l'apoptose des neurones que l'expression des protéases caspase 3 et des protéines Bcl-2 ont été mesurés. Résultats: Si on la compare au traitement à base de solution saline administré au groupe témoin, la polythérapie à base de VEGF et de NGF, lorsqu'administrée 5 heures ou 8 heures à la suite de l'AVC, a su réduire de façon notable le volume des infarctus, le contenu en eau, l'apoptose des neurones et l'expression des protéases caspase 3. Elle a également permis de réguler à la hausse l'expression des protéines Bcl-2 en plus d'entraîner une amélioration de la récupération fonctionnelle (p < 0,01 pour ces deux aspects). Ainsi donc, plus tôt l'on opte pour cette polythérapie, meilleure sera la neuroprotection encourue. Ces résultats démontrent que la polythérapie à base de VEGF et de NGF procure des effets neuroprotecteurs. Quant au délai d'administration de ce traitement combinatoire, il devrait être d'au moins 8 heures à la suite d'un AVC, ce qui est plus élevé que la monothérapie.

Selected Natural Attenuation Monitoring Data, Operable Unit 1, Naval Undersea Warfare Center, Division Keyport, Washington, June 2006

USGS Publications Warehouse

Dinicola, R.S.; Huffman, R.L.

2007-01-01

Previous investigations have shown that natural attenuation and biodegradation of chlorinated volatile organic compounds (VOCs) are substantial in shallow ground water beneath the 9-acre former landfill at Operable Unit 1 (OU 1), Naval Undersea Warfare Center, Division Keyport, Washington. The U.S. Geological Survey (USGS) has continued to monitor ground-water geochemistry to assure that conditions remain favorable for contaminant biodegradation. This report presents ground-water geochemical and selected VOC data collected at OU 1 by the USGS during June 12-14, 2006, in support of long-term monitoring for natural attenuation. For June 2006, the strongly reducing conditions (sulfate reduction and methanogenesis) most favorable for reductive dechlorination of VOCs were inferred for 5 of 15 upper-aquifer sites in the northern and southern phytoremediation plantations. Predominant redox conditions in ground water from the intermediate aquifer just downgradient from the landfill remained mildly reducing and somewhat favorable for reductive dechlorination. Since about 2003, measured dissolved hydrogen concentrations in the upper aquifer generally have been lower than those previously measured, although methane and sulfide have continued to be detected throughout the upper aquifer beneath the landfill. Overall, no widespread changes in ground-water redox conditions were measured that should result in either more or less efficient biodegradation of chlorinated VOCs. For the northern plantation in 2006, chlorinated VOC concentrations at piezometers P1-3 and P1-4 were lower than previously measured, and trichloroethene (TCE), cis-1,2-dichloroethene (cis-DCE), or vinyl chloride (VC) were not detected at piezometers P1-1 and P1-5. The steady decrease in contaminant concentrations and the continued detection of the reductive dechlorination end-products ethene and ethane have been consistent throughout the upper aquifer beneath the northern plantation. For the southern plantation in 2006, changes in chlorinated VOC concentrations at the piezometers were highly variable. At piezometer P1-9, the 2006 total chlorinated VOC concentration as well as the concentrations of cis-DCE and VC were measured at their highest levels to date; contaminant concentrations substantially decreased at piezometer P1-9 between June 2004 and June 2005. The reasons for the 2004-05 decrease in concentrations or the 2005-06 increase in concentrations are unknown. At piezometer P1-10, the consistent temporal trend of decreasing chlorinated VOC concentrations measured since 1999 ended, and the concentration of total chlorinated VOC in 2006 was the highest measured since 1999. The reductive dechlorination end-product ethene was measured at concentrations as high as 1,300 micrograms per liter in the upper aquifer beneath the southern plantation, which is reliable evidence that reductive dechlorination of VOCs is ongoing.

Identification of key characteristics of male reproductive toxicants as an approach for screening and sorting mechanistic evidence.

EPA Science Inventory

The application of systematic review practices in human health assessment includes integration of multi-disciplinary evidence from epidemiological, experimental, and mechanistic studies. Although mode of action analysis relies on the evaluation of mechanistic and toxicological ou...

Differential partitioning of triterpenes and triterpene esters in apple peel

USDA-ARS?s Scientific Manuscript database

Apple peel functions as a protective barrier against biotic and abiotic stresses, and preserving the integrity and appearance of peel critical for market acceptance. Peel epidermal cells and epicuticular wax are a rich source of secondary metabolites, including triterpenes. Several studies have ou...

Long-Term Monitoring Network Optimization Evaluation for Operable Unit 2, Bunker Hill Mining and Metallurgical Complex Superfund Site, Idaho

EPA Pesticide Factsheets

This report presents a description and evaluation of the ground water and surface water monitoring program associated with the Bunker Hill Mining and Metallurgical Complex Superfund Site (Bunker Hill) Operable Unit (OU) 2.

Comparing Faculty Perceptions of Sustainability Teaching at Two US Universities

ERIC Educational Resources Information Center

Tziganuk, Ashlee; Gliedt, Travis

2017-01-01

Purpose: This study aims to examine and compare faculty perceptions of the process of institutionalizing sustainability, developing sustainability pedagogy and activating key sustainability competencies between the University of Oklahoma (OU) and Arizona State University (ASU). Design/methodology/approach: Semi-structured interviews were conducted…

Work Plan for Comprehensive Groundwater Sampling (Operable Unit 2) April 2012

EPA Pesticide Factsheets

April 27, 2012 cover letter from Kirk Kessler, EPS, to Galo Jackson, EPA Region 4 and two OU2-related work plans for sampling at the LCP Chemicals Superfund Site, GA. Region ID: 04 DocID: 10922560, DocDate: 04-27-2012

Global and Regional Real-time Systems for Flood and Drought Monitoring and Prediction

NASA Astrophysics Data System (ADS)

Hong, Y.; Gourley, J. J.; Xue, X.; Flamig, Z.

2015-12-01

A Hydrometeorological Extreme Mapping and Prediction System (HyXtreme-MaP), initially built upon the Coupled Routing and Excess STorage (CREST) distributed hydrological model, is driven by real-time quasi-global TRMM/GPM satellites and by the US Multi-Radar Multi-Sensor (MRMS) radar network with dual-polarimetric upgrade to simulate streamflow, actual ET, soil moisture and other hydrologic variables at 1/8th degree resolution quasi-globally (http://eos.ou.edu) and at 250-meter 2.5-mintue resolution over the Continental United States (CONUS: http://flash.ou.edu).­ Multifaceted and collaborative by-design, this end-to-end research framework aims to not only integrate data, models, and applications but also brings people together (i.e., NOAA, NASA, University researchers, and end-users). This presentation will review the progresses, challenges and opportunities of such HyXTREME-MaP System used to monitor global floods and droughts, and also to predict flash floods over the CONUS.

Superfund record of decision amendment (EPA Region 5): Ott/Story/Cordova Chemical Co., Dalton Township, MI, February 26, 1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This decision document presents the amendment to the Record of Decision (ROD) for Operable Unit (O.U.) No. 3 at the Ott/Story/Cordova Site (the Site) in Muskegon, MI. On September 27, 1993 a ROD was signed for the O.U. No. 3 Remedial Action choosing Low Temperature Thermal Desorption (LTTD) to treat contaminated plant area soils and sediments in Little Bear Creek and its unnamed tributary. This amendment to the ROD: eliminates LTTD from the remedy; revises the volume of soils to be remediated by excavation and off-site disposal as a result of an understanding that the land use for the sitemore » will remain industrial instead of residential as provided for in the 1993 ROD; requires regular sampling of surface water and sediments to determine the need for remedial action in the Little Bear Creek; and requires deed restrictions to insure that use of the site remains industrial.« less

Superfund Record of Decision (EPA Region 5): Reilly Tar and Chemical Corporation Site, St. Peter Aquifer, St. Louis Park, MN. (Third remedial action), September 1990

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-09-28

The 80-acre Reilly Tar and Chemical (St. Louis Park) site is a former coal tar distillation and wood preserving plant in St. Louis Park, Minnesota. The site overlies a complex system of aquifers, including the St. Peter aquifer that provide drinking water to area residences. The St. Peter Aquifer contains one municipal well, which is used during periods of peak demand, however, the majority of the drinking water in St. Louis Park is obtained from deeper aquifers. From 1917 to 1972, wastewater containing creosote and coal tar was discharged to onsite surface water, and as a result, small wastewater spillsmore » occurred into onsite soil. The ROD addresses Operable Unit 4 (OU4), remediation of the St. Peter aquifer. A subsequent ROD will address any remaining site problems as OU3. The primary contaminants of concern affecting the ground water are organics including PAHs and phenols.« less

Hémophilie B mineure révélée par une hémorragie cérébrale: à propos d'un cas

PubMed Central

Naji, Abdelhalim; Rkain, Maria; Amrani, Rim; Benajiba, Noufissa

2015-01-01

L'hémorragie intracrânienne (HIC) du nouveau-né à terme est une pathologie rare, leur prévalence est estimée à 2% des naissances vivantes. Les manifestations cliniques sont variables et non spécifique. Les causes d'HIC sont multiples et souvent intriquées, les mécanismes physiopathologiques principaux sont la dysrégulation du débit cérébral, une obstruction des vaisseaux ou une coagulation intravasculaire; ou une lésion directe par traumatisme. Nous rapportons le cas d'un nourrisson d'un mois qui a été admis dans notre service pour prendre en charge des convulsions associées à une pâleur cutanéomuqueuse, suite à laquelle l'examen biologique a mis fortuitement en faveur une hémophilie mineure sur une maladie hémorragique tardive. PMID:26491519

A importância de reconhecer a síndrome antifosfolípide na medicina vascular

PubMed Central

Funke, Andreas; Danowski, Adriana; de Andrade, Danieli Castro Oliveira; Rêgo, Jozelia; Levy, Roger Abramino

2017-01-01

Resumo A síndrome antifosfolipíde (SAF) é uma doença autoimune sistêmica caracterizada por trombose arterial ou venosa recorrente e/ou morbidade gestacional e pela presença dos anticorpos antifosfolipídeos, podendo apresentar outras manifestações vasculares, como microangiopatia, arteriopatia crônica e SAF catastrófica. Determinados testes laboratoriais para a síndrome (por exemplo, o anticoagulante lúpico) podem sofrer interferência do uso de medicações anticoagulantes, dificultando o diagnóstico. A fisiopatologia da SAF é complexa, sendo enumerados no texto diversos mecanismos patogênicos relacionados à coagulação, ao endotélio e às plaquetas. Por fim, discutimos o tratamento da SAF de acordo com a presença e o tipo de manifestações clínicas, o uso dos anticoagulantes orais diretos e o manejo perioperatório de pacientes com SAF. PMID:29930638

Martian atmospheric O3 retrieval development for the NOMAD-UVIS spectrometer

NASA Astrophysics Data System (ADS)

Hewson, W.; Mason, J. P.; Leese, M.; Hathi, B.; Holmes, J.; Lewis, S. R.; Iriwin, P. G. J.; Patel, M. R.

2017-09-01

The composition of atmospheric trace gases and aerosols is a highly variable and poorly constrained component of the martian atmosphere, and by affecting martian climate and UV surface dose, represents a key parameter in the assessment of suitability for martian habitability. The ExoMars Trace Gas Orbiter (TGO) carries the Open University (OU) designed Ultraviolet and VIsible Spectrometer (UVIS) instrument as part of the Belgian-led Nadir and Occultation for MArs Discovery (NOMAD) spectrometer suite. NOMAD will begin transmitting science observations of martian surface and atmosphere back-scattered UltraViolet (UV) and visible radiation in Spring 2018, which will be processed to derive spatially and temporally averaged atmospheric trace gas and aerosol concentrations, intended to provide a better understanding of martian atmospheric photo-chemistry and dynamics, and will also improve models of martian atmospheric chemistry, climate and habitability. Work presented here illustrates initial development and testing of the OU's new retrieval algorithm for determining O3 and aerosol concentrations from the UVIS instrument.

Methodes de calcul des forces aerodynamiques pour les etudes des interactions aeroservoelastiques

NASA Astrophysics Data System (ADS)

Biskri, Djallel Eddine

L'aeroservoelasticite est un domaine ou interagissent la structure flexible d'un avion, l'aerodynamique et la commande de vol. De son cote, la commande du vol considere l'avion comme une structure rigide et etudie l'influence du systeme de commande sur la dynamique de vol. Dans cette these, nous avons code trois nouvelles methodes d'approximation de forces aerodynamiques: Moindres carres corriges, Etat minimal corrige et Etats combines. Dans les deux premieres methodes, les erreurs d'approximation entre les forces aerodynamiques approximees par les methodes classiques et celles obtenues par les nouvelles methodes ont les memes formes analytiques que celles des forces aerodynamiques calculees par LS ou MS. Quant a la troisieme methode, celle-ci combine les formulations des forces approximees avec les methodes standards LS et MS. Les vitesses et frequences de battement et les temps d'executions calcules par les nouvelles methodes versus ceux calcules par les methodes classiques ont ete analyses.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The 26-acre Shaw Avenue Dump site is a chemical waste site in Charles City, Floyd County, Iowa. Land use in the area is predominantly residential. From 1899 to 1964, Charles City used the site as a municipal landfill for waste incineration, and disposal of liming sludge from the city's publicly owned treatment works (POTW) and asphaltic materials continue to be disposed of in the landfill. Between 1977 and 1981, the State issued reports based on studies of the site and surface water that documented elevated levels of metals in an abandoned gravel pit near the site. The Record of Decisionmore » (ROD) addresses the chemical fill and surrounding contaminated soil, and the underground gasoline tank as Operable Unit 1 (OU1). A future ROD will address contaminated ground water as OU2. The primary contaminants of concern affecting the soil and debris are VOCs including benzene, toluene, and xylenes; other organics including PAHs; metals including arsenic and lead; and other inorganics. The selected remedial action for the site is included.« less

[Case report of melanoma-associated retinopathy associated with positive auto-antibodies against retinal bipolar cells].

PubMed

Hanaya, Junko; Nakamura, Yasuko; Nejima, Ryouhei; Miyata, Kazunori; Mera, Kentarou; Ohguro, Hiroshi; Yamamoto, Shuichi

2011-06-01

We report a case of melanoma-associated retinopathy (MAR) associated with positive auto-antibodies against retinal bipolar cells, which has been rarely reported in Japan. A 33 year-old woman noticed shimmering vision, photopsias, blurred vision, and night blindness OS in April 2009, and visited Kagoshima Miyata Eye Clinic in May 2009. She had been continuously treated for malignant melanoma on her left finger since 2007. At her initial visit, the corrected visual acuity was 1.5 OD and 1.2 OS, and slit-lamp examination revealed clear ocular media OU. Funduscopic examination showed normal appearance of the retina OU, except for a mild narrowing of the retinal arteries OS. Humphrey field analyzer revealed a reduction of retinal sensitivity within the central 30 degrees OS. The maximum left eye response of electroretinogram (ERG) showed a negative waveform. The immuno-cytochemical test revealed antibodies against retinal bipolar cells, which confirmed the diagnosis of MAR. Characteristic subjective symptoms, Humphrey field analyzer and ERG are useful for the diagnosis of MAR.

A Case of Bilateral Descemet's Membrane and Subepithelial Opacity: In vivo Laser Confocal Microscopic Study.

PubMed

Hatta, Yukiko; Yokogawa, Hideaki; Kobayashi, Akira; Torisaki, Makoto; Sugiyama, Kazuhisa

2013-01-01

To report the in vivo laser confocal microscopy findings from a patient with Descemet's membrane and subepithelial opacity OU. A healthy 41-year-old male with Descemet's membrane and subepithelial opacity OU was studied. Routine ophthalmic examination, standard slit-lamp biomicroscopy, and in vivo laser confocal microscopic analysis of the entire corneal layer were performed. Slit-lamp biomicroscopy revealed subepithelial opacity in the mid-peripheral to peripheral cornea and numerous opacities located at the level of Descemet's membrane. It was difficult to distinguish the precise histological location of the opacity. In vivo laser confocal microscopy showed numerous hyperreflective particles in the subepithelium to superficial stroma and hyperreflectivity of Descemet's membrane. No abnormalities could be detected in the epithelial cell layer, midstromal layer, deep stromal layer, or endothelial cell layer. Although the origin of the corneal opacities was unclear, in vivo laser confocal microscopy was useful for observing microstructural abnormalities in a case of Descemet's membrane and subepithelial opacity.

A Case of Bilateral Descemet's Membrane and Subepithelial Opacity: In vivo Laser Confocal Microscopic Study

PubMed Central

Hatta, Yukiko; Yokogawa, Hideaki; Kobayashi, Akira; Torisaki, Makoto; Sugiyama, Kazuhisa

2013-01-01

Purpose To report the in vivo laser confocal microscopy findings from a patient with Descemet's membrane and subepithelial opacity OU. Case Report A healthy 41-year-old male with Descemet's membrane and subepithelial opacity OU was studied. Routine ophthalmic examination, standard slit-lamp biomicroscopy, and in vivo laser confocal microscopic analysis of the entire corneal layer were performed. Slit-lamp biomicroscopy revealed subepithelial opacity in the mid-peripheral to peripheral cornea and numerous opacities located at the level of Descemet's membrane. It was difficult to distinguish the precise histological location of the opacity. In vivo laser confocal microscopy showed numerous hyperreflective particles in the subepithelium to superficial stroma and hyperreflectivity of Descemet's membrane. No abnormalities could be detected in the epithelial cell layer, midstromal layer, deep stromal layer, or endothelial cell layer. Conclusion Although the origin of the corneal opacities was unclear, in vivo laser confocal microscopy was useful for observing microstructural abnormalities in a case of Descemet's membrane and subepithelial opacity. PMID:23626574

Énergie photovoltaïque : matériaux utilisés et perspectives

NASA Astrophysics Data System (ADS)

Marfaing, Y.

2002-04-01

Les matériaux pour la conversion photovoltaïque sont des semi-conducteurs dont la largeur de bande interdite peut se situer dans l'intervalle 1 - 1,8 eV. Les principes physiques de l'effet photovoltaïque sont d'abord rappelés afin de mettre en évidence les relations nécessaires entre les caractéristiques optiques et électroniques du semi-conducteur et l'épaisseur de la structure de conversion ou cellule. Les matériaux actuellement utilisés ou étudiés sont ensuite passés en revue en commençant par le silicium cristallin massif puis en décrivant le vaste secteur des couches minces : silicium amorphe, composés polycristallins, silicium cristallisé en film mince. Les développements attendus dans chacune de ces filières sont présentés ainsi que les recherches en cours sur d'autres types de matériaux et de structures.

Trombose venosa profunda e vírus chicungunha

PubMed Central

Marques, Marcos Arêas; Adami de Sá, Fernanda Penza; Lupi, Otília; Brasil, Patricia; von Ristow, Arno

2017-01-01

Resumo Algumas infecções virais sistêmicas podem estar relacionadas ao desenvolvimento de trombose venosa profunda e/ou embolia pulmonar. Essa associação já está bem descrita em pacientes com infeções pelo vírus da imunodeficiência humana (HIV), hepatite C ou influenza. Recentemente introduzido no continente americano, o vírus chicungunha, agente etiológico da febre de chicungunha, ainda não tem essa relação bem sedimentada, mas com o aumento progressivo de sua incidência e pelo fato dessa infecção causar, muitas vezes, uma restrição severa da locomoção por poliartralgia e uma possível lesão endotelial direta, casos de tromboembolismo venoso podem começar a ser descritos. Neste relato de caso, descrevemos um paciente que desenvolveu trombose de veia poplítea direita durante internação para tratamento de febre por infecção por vírus chicungunha e poliartralgia severa. PMID:29930626

AVERAGE ANNUAL SOLAR UV DOSE OF THE CONTINENTAL US CITIZEN

EPA Science Inventory

The average annual solar UV dose of US citizens is not known, but is required for relative risk assessments of skin cancer from UV-emitting devices. We solved this problem using a novel approach. The EPA's "National Human Activity Pattern Survey" recorded the daily ou...

Consent Decree for RD/RA for OU-4 - Weyerhaeuser Co. Plymouth Treating Plant. Civil Action Number 4:08-CV-179-D

EPA Pesticide Factsheets

Contains legal agreement for the Domtar Paper Company LLC (formerly Weyerhaeuser Company) site under CERCLA Sections 106 and 107, Martin County, North Carolina, January 7, 2009 DocID: 10452888, DocDate: 01-07-2009

L’évaluation du risque cardiaque avant l’utilisation de stimulants chez les enfants et les adolescents

PubMed Central

Bélanger, SA; Warren, AE; Hamilton, RM; Gray, C; Gow, RM; Sanatani, S; Côté, J-M; Lougheed, J; LeBlanc, J; Martin, S; Miles, B; Mitchell, C; Gorman, DA; Weiss, M; Schachar, R

2009-01-01

Les décisions en matière de réglementation et les documents scientifiques au sujet de la prise en charge du trouble de déficit de l’attention avec hyperactivité (TDAH) soulèvent des questions quant à l’innocuité des médicaments et à l’évaluation convenable à effectuer avant le traitement afin de déterminer la pertinence d’une pharmacothérapie. Ce constat est particulièrement vrai en présence de cardiopathies structurelles ou fonctionnelles. Le présent article contient l’analyse des données disponibles, y compris les publications révisées par des pairs, des données tirées du site Web de la Food and Drug Administration des États-Unis au sujet des réactions indésirables déclarées chez des enfants qui prennent des stimulants, ainsi que des données de Santé Canada sur le même problème. Des lignes directrices consensuelles sur l’évaluation pertinente sont proposées d’après l’apport des membres de la Société canadienne de pédiatrie, de la Société canadienne de cardiologie et de l’Académie canadienne de psychiatrie de l’enfant et de l’adolescent, qui possèdent notamment des compétences et des connaissances précises tant dans le secteur du TDAH que de la cardiologie pédiatrique. Le présent document de principes prône une anamnèse et un examen physique détaillés avant la prescription de stimulants et s’attarde sur le dépistage des facteurs de risque de mort subite, mais il ne contient pas de recommandations systématiques de dépistage électrocardiographique ou de consultations avec un spécialiste en cardiologie, à moins que les antécédents ou que l’examen physique ne le justifient. Le document contient un questionnaire pour repérer les enfants potentiellement vulnérables à une mort subite (quel que soit le type de TDAH ou les médicaments utilisés pour le traiter). Même si les recommandations dépendent des meilleures données probantes disponibles, le comité s’entend pour affirmer que d’autres recherches s’imposent pour optimiser l’approche de ce scénario clinique courant.

Les campagnes communautaires de promotion du depistage VIH en Afrique de l’Ouest : perceptions des usagers au Burkina Faso

PubMed Central

Desclaux, Alice; Ky-Zerbo, Odette; Somé, Jean-François; Makhlouf-Obermeyer, Carla

2014-01-01

Résumé La politique actuelle de lutte contre le sida qui repose sur l’extension de l’accès aux traitements et à la prévention exige qu’une proportion élevée de la population connaisse son statut en matière de VIH. Pour cela, l’OMS a proposé le développement de stratégies communautaires délivrant le dépistage et le conseil au-delà des services de soins, comme le test à domicile ou les campagnes de sensibilisation et dépistage de grande envergure, appliqués en Afrique australe et de l’Est. Pour définir les stratégies pertinentes dans des régions de basse prévalence comme l’Afrique de l’Ouest, les expériences communautaires de promotion du dépistage doivent y être évaluées. Cet article présente une évaluation des campagnes au Burkina Faso du point de vue des usagers. Dans le cadre d’un projet sur les pratiques et l’éthique du dépistage dans quatre pays africains (MATCH), une enquête qualitative spécifique a été menée pendant la campagne de 2008, auprès de personnes ayant fait le test pendant la campagne, ayant fait le test hors campagne ou n’ayant pas fait le test. Les appréciations sont globalement très favorables aux campagnes, notamment à cause de l’information dispensée, l’accessibilité des sites, la gratuité du test, la qualité des services et l’effet d’entrainement. Les limites ou critiques sont essentiellement liées à l’affluence ou à la crainte de ne pas être soutenu en cas de résultat positif. La démarche de recours au test ne fait plus l’objet de suspicion, au moins pendant la campagne. Cette « normalisation » du recours au test et la mobilisation collective facilitent des pratiques en groupe, ce qui peut rendre difficile de garder son statut VIH secret. L’évaluation des campagnes par les usagers les présente comme une opportunité pour accéder facilement au test et pour communiquer à ce sujet dans divers espaces sociaux à partir des informations délivrées sur le VIH. PMID:24755264

La stimulation magnétique transcrânienne (SMT) dans la recherche fondamentale et clinique en neuroscience

PubMed Central

Valero-Cabré, Antoni; Pascual-Leone, Alvaro; Coubard, Olivier A.

2011-01-01

Introduction Les méthodes de stimulation cérébrale non invasives telles que la Stimulation Magnétique Transcrânienne (SMT) sont largement utilisées pour établir des inférences causales sur les relations entre cerveau et comportement. Des applications cliniques basées sur la SMT ont également été développées pour traiter des affections neurologiques ou psychiatriques comme la dépression, la dystonie, la douleur, les acouphènes ou les séquelles d’accident vasculaire cérébral. État des connaissances La SMT fonctionne en induisant de manière non invasive et de manière focale des courants électriques dans des régions corticales, modulant ainsi leur niveau d’activité de façon variable suivant la fréquence, le nombre d’impulsions, les intervalles et la durée de stimulation utilisés. S’agissant du cortex moteur, on sait par exemple que les patterns d’impulsions de SMT à basse fréquence ou ceux délivrées de manière continue tendent à déprimer l’activité locale, tandis que la SMT à haute fréquence et discontinus tend à la potentialiser. Outre ses effets locaux, la SMT peut aussi avoir des effets à distance sur les régions cérébrales, véhiculés par les connections anatomiques et qui dépendent de l’efficacité et du signe de ces connexions. Perspectives Dans le domaine de la recherche fondamentale et des applications thérapeutiques, l’utilisation efficace de la SMT requiert, cependant, la compréhension approfondie de ses principes opérationnels, de ses risques, de ses potentialités et de ses limites. Dans cet article, nous présentons les principes par lesquels opèrent les méthodes de stimulation cérébrale non invasive, et en particulier la SMT. Conclusion À l’issue de sa lecture, le lecteur sera en mesure de discuter de façon critique les études scientifiques et cliniques utilisant la SMT, ainsi que de concevoir des applications SMT suivant une hypothèse a priori dans le domaine de la recherche en neuroscience fondamentale et/ou clinique. PMID:21420698

Evaluation de la qualite osseuse par les ondes guidees ultrasonores =

NASA Astrophysics Data System (ADS)

Abid, Alexandre

La caracterisation des proprietes mecaniques de l'os cortical est un domaine d'interet pour la recherche orthopedique. En effet, cette caracterisation peut apporter des informations primordiales pour determiner le risque de fracture, la presence de microfractures ou encore depister l'osteoporose. Les deux principales techniques actuelles de caracterisation de ces proprietes sont le Dual-energy X-ray Absorptiometry (DXA) et le Quantitative Computed Tomogaphy (QCT). Ces techniques ne sont pas optimales et presentent certaines limites, ainsi l'efficacite du DXA est questionnee dans le milieu orthopedique tandis que le QCT necessite des niveaux de radiations problematiques pour en faire un outil de depistage. Les ondes guidees ultrasonores sont utilisees depuis de nombreuses annees pour detecter les fissures, la geometrie et les proprietes mecaniques de cylindres, tuyaux et autres structures dans des milieux industriels. De plus, leur utilisation est plus abordable que celle du DXA et n'engendrent pas de radiation ce qui les rendent prometteuses pour detecter les proprietes mecaniques des os. Depuis moins de dix ans, de nombreux laboratoires de recherche tentent de transposer ces techniques au monde medical, en propageant les ondes guidees ultrasonores dans les os. Le travail presente ici a pour but de demontrer le potentiel des ondes guidees ultrasonores pour determiner l'evolution des proprietes mecaniques de l'os cortical. Il commence par une introduction generale sur les ondes guidees ultrasonores et une revue de la litterature des differentes techniques relatives a l'utilisation des ondes guidees ultrasonores sur les os. L'article redige lors de ma maitrise est ensuite presente. L'objectif de cet article est d'exciter et de detecter certains modes des ondes guides presentant une sensibilite a la deterioration des proprietes mecaniques de l'os cortical. Ce travail est realise en modelisant par elements finis la propagation de ces ondes dans deux modeles osseux cylindriques. Ces deux modeles sont composes d'une couche peripherique d'os cortical et remplis soit d'os trabeculaire soit de moelle osseuse. Ces deux modeles permettent d'obtenir deux geometries, chacune propice a la propagation circonferentielle ou longitudinale des ondes guidees. Les resultats, ou trois differents modes ont pu etre identifies, sont compares avec des donnees experimentales obtenues avec des fantomes osseux et theoriques. La sensibilite de chaque mode pour les differents parametres des proprietes mecaniques est alors etudiee ce qui permet de conclure sur le potentiel de chaque mode quant a la prediction de risque de fracture ou de presence de microfractures.

Simplificando a luneta com lente de óculos

NASA Astrophysics Data System (ADS)

Canalle, J. B. G.; de Souza, A. C. F.

2003-08-01

A principal ferramenta de trabalho do astrônomo é o telescópio. O manuseio do mesmo é sempre motivo de enorme curiosidade por parte de alunos do ensino fundamental ou médio e até mesmo dos respectivos professores. Visando propiciar o acesso de alunos e professores ou interessados em geral a uma luneta de fácil construção, com materiais alternativos, de fácil localização no comércio, de baixo custo, resistente ao manuseio de alunos, simplificamos a montagem de uma luneta construída com lente de óculos, de 1 ou 2 graus positivos, e monóculo de fotografia, publicado por este autor no CCEF, vol.11(3), 212, 1994. Esta luneta, a qual permite ver as crateras lunares, apresentava como maior dificuldade de construção o tripé e o local de formação da imagem. Substituímos o tripé de madeira por uma simples garrafa PET de 2 litros cheia d'água. No lugar da ocular usamos a lente do monóculo de fotografia (ou visor de fotografia) encaixado dentro de uma bucha de redução curta, de 40 x 32 mm, e esta não mais dentro de uma luva (conexão hidráulica) de 40 mm de diâmetro, mas sim encostada no próprio tubo de PVC móvel (o qual permite o ajuste do foco) de 40 mm de diâmetro e presa a este por outro tubo de 40 mm de diâmetro e 10 cm de comprimento, serrado ao longo do seu comprimento. Com isto podemos ajustar a posição deste tubo de 10 cm também para que uma das suas extremidades coincida com o local de formação da imagem. Desta forma o observador saberá o local exato da formação da imagem, o que não era evidente na montagem anterior e causava uma dificuldade inicial até se descobrir a posição exata em que se deveria colocar o olho. Deste maneira, a montagem inicial que já era simples ficou ainda mais simples, mais barata e mais confortável para o uso. Um exemplar da mesma será exposto durante a XXIX Reunião Anual da Sociedade Astronômica Brasileira para inspeção e uso dos participantes.

Aborder la syllogomanie en médecine familiale

PubMed Central

Frank, Christopher; Misiaszek, Brian

2012-01-01

Résumé Objectif Examiner comment se présente la syllogomanie et suggérer aux médecins de famille des approches et des ressources pour sa prise en charge. Source des données On a fait une recension dans PubMed de 2001 à mai 2011. Le mot-clé MeSH hoarding a été utilisé pour identifier la recherche à ce sujet et passer en revue les articles portant sur les aspects neuropsychologiques de l’accumulation pathologique, son diagnostic et son traitement. Message principal La syllogomanie ou accumulation pathologique est souvent un problème peu évident en médecine familiale. Les patients qui ont une syllogomanie se présentent souvent à cause d’un événement sentinelle comme une chute ou un incendie à leur domicile. Quoique la syllogomanie soit traditionnellement associée à un trouble obsessionnel-compulsif, le plus souvent, les patients ont une maladie systémique secondaire associée à un comportement syllogomaniaque ou ont une syllogomanie en l’absence de caractéristiques compulsives considérables. On s’attend à ce que la syllogomanie soit incluse dans la 5e édition du Manuel diagnostique et statistique des troubles mentaux. Si possible, il vaut mieux prendre en charge la syllogomanie selon une approche multidisciplinaire. Un nombre grandissant de centres offrent des programmes pour améliorer les symptômes ou réduire les dangers. Il a été démontré que la prise en charge pharmacologique a une certaine utilité pour traiter les causes secondaires. Chez les personnes plus âgées, des problèmes comme la démence, la dépression et la toxicomanie sont souvent associés à un comportement d’accumulation pathologique. Il faudrait essayer de maintenir les patients à domicile dans la mesure du possible, mais l’évaluation de la capacité devrait guider l’approche à adopter. Conclusion L’accumulation pathologique est plus fréquente que ne le pensent les médecins de famille. Si on identifie une syllogomanie, il faudrait rechercher des ressources locales pour contribuer à la prise en charge. Il faut évaluer et traiter les causes sous-jacentes lorsqu’elles sont cernées. On s’attend à ce que la syllogomanie primaire compte parmi les nouveaux diagnostics dans la 5e édition du Manuel diagnostique et statistique des troubles mentaux.

Translation into French of: “Changes to publication requirements made at the XVIII International Botanical Congress in Melbourne – what does e-publication mean for you?”. Translated by Christian Feuillet and Valéry Malécot Changements des conditions requises pour la publication faits au XVIII e Congrès International de Botanique à Melbourne – qu’est-ce que la publication électronique représente pour vous?

PubMed Central

Knapp, Sandra; McNeill, John; Turland, Nicholas J.

2011-01-01

Résumé Les changements au Code International de Nomenclature Botanique sont décidés tous les 6 ans aux Sections de Nomenclature associées aux Congrès Internationaux de Botanique (CIB). Le XVIIIe CIB se tenait à Melbourne, Australie; la Section de Nomenclature s’est réunie les 18-22 juillet 2011 et ses décisions ont été acceptées par le Congrès en session plénière le 30 juillet. Suite à cette réunion, plusieurs modifications importantes ont été apportées au Code et vont affecter la publication de nouveaux noms. Deux de ces changements prendront effet le 1er janvier 2012, quelques mois avant que le Code de Melbourne soit publié. Les documents électroniques publiés en ligne en ‘Portable Document Format’ (PDF) avec un ‘International Standard Serial Number’ (ISSN) ou un ‘International Standard Book Number’ (ISBN) constitueront une publication effective, et l’exigence d’une description ou d’une diagnose en latin pour les noms des nouveaux taxa sera changée en l’exigence d’une description ou d’une diagnose en latin ou en anglais. De plus, à partir du 1er janvier 2013, les noms nouveaux des organismes traités comme champignons devront, pour que la publication soit valide, inclure dans le protologue (tous ce qui est associé au nom au moment de la publication valide) la citation d’un identifiant (‘identifier’) fourni par un dépôt reconnu (tel MycoBank). Une ébauche des nouveaux articles concernant la publication électronique est fournie et des conseils de bon usage sont esquissés. Pour encourager la diffusion des changements adoptés au Code International de Nomenclature pour les algues, les champignons et les plantes, cet article sera publié dans BMC Evolutionary Biology, Botanical Journal of the Linnean Society, Brittonia, Cladistics, MycoKeys, Mycotaxon, New Phytologist, North American Fungi, Novon, Opuscula Philolichenum, PhytoKeys, Phytoneuron, Phytotaxa, Plant Diversity and Resources, Systematic Botany et Taxon. PMID:22287925

Aspects of choosing appropriate concepts for modelling groundwater resources in regional integrated water resources management Examples from the Neckar (Germany) and Ouémé catchment (Benin)

NASA Astrophysics Data System (ADS)

Barthel, R.; Jagelke, J.; Götzinger, J.; Gaiser, T.; Printz, Andreas

Two regional groundwater flow models (Neckar catchment, Germany, 14,000 km 2, and Southern Ouémé Basin, Benin, 11,000 km 2) were developed within the framework of the integrated management project ‘RIVERTWIN’ ( www.rivertwin.org). Both models were evaluated with respect to the question if the chosen modelling approaches (multi-layered finite difference numerical flow modelling, steady state and transient) are appropriate in view of the existing management problems in the catchments, the data availability and the hydrogeological and hydrological conditions in the basins. It is shown that neither the model in the well-investigated, data-rich basin in Western Europe with its highly developed water related infrastructure, nor the model in the hydrogeologically less well-known and less developed basin in Western Africa provide results that are fully applicable to the main regional management tasks. In the case of the Ouémé, the groundwater related problems are foremost of local character and therefore cannot be addressed by regional models in a meaningful way. Data scarcity and complex, unfavourable geological conditions (crystalline rocks, discontinuous aquifers) support the conclusion that numerical 3D groundwater flow models are currently not helpful to manage groundwater related management problems in the Ouémé basin. A better understanding of regional hydrological surface and subsurface processes is required first. Methods for a reliable estimation of groundwater recharge and subsequently groundwater availability were identified as the most urgently needed tool for meaningful groundwater management in view of climatic, demographic and land use change. In the Neckar catchment the results of the analysis are less pronounced; here regional groundwater problems could clearly benefit from a physically based 3D model since the hydrogeological system is strictly stratified with several important aquifers in the vertical sequence. As a general conclusion it can be stated that regional scale groundwater flow modelling concepts seem to be difficult to integrate in management systems and difficult to transfer from one basin to another. This means the question of how to represent the groundwater resources appropriately has to be discussed very thoroughly for any new integrated water resources management problem. It is not possible to give a final recommendation on which modelling concept is the most appropriate one in regional integrated modelling and management. Hence, this article is only intended to provide an in depth discussion of the aspects that need to be considered in the process of choosing appropriate modelling concepts.

75 FR 34405 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-17

... future actions under Superfund. This partial deletion pertains to the surface media (soil, surface water... in contamination of structures, soil, surface water, and groundwater. As a result of this... Superfund Site located upgradient (south) of RMA (1990). OU 03: On-Post--Addresses soil and groundwater...

Jeux droles ou droles de jeux. (Funny Games or Strange Games.)

ERIC Educational Resources Information Center

Care, Jean-Marc

1983-01-01

Role playing differs from the more static teaching technique of simulation in its incorporation of originality and theatricality. From preparation to presentation, it is important to retain the element of play, avoid techniques of or tendencies toward psychodrama, and hold the pedagogical or evaluative purposes in mind. (MSE)

CHILDREN'S ENVIRONMENTAL HEALTH AND DISEASE PREVENTION RESEARCH CENTERS: FORMATIVE CENTERS

EPA Science Inventory

We expect, at the end of this project, to be able to 1) characterize sources of maternal exposure to BPA, the relationship between maternal and intrauterine levels of BPA and 2) gain an in‐depth understanding of BPA affects early development. We anticipate this will improve ou...

Spatio-temporal distribution of stored-product inects around food processing and storage facilities

USDA-ARS?s Scientific Manuscript database

Grain storage and processing facilities consist of a landscape of indoor and outdoor habitats that can potentially support stored-product insect pests, and understanding patterns of species diversity and spatial distribution in the landscape surrounding structures can provide insight into how the ou...

An illustrated analysis of North Carolina traffic crash statistics for 2005

DOT National Transportation Integrated Search

2005-01-01

Comparing the statistics of 2004 with 2005, there : was a 1.7% decrease in the number of fatalities, and : a 3.6% decrease in the number of traffic crashes : reported. A crash occurred every 2.4 minutes and a : person was killed every 5.7 hours on ou...

Fistule vesico-sigmoïdienne compliquant une hydatidose intestinale: à propos d'un cas rare

PubMed Central

Lahyani, Mounir; Jabbour, Younes; Karmouni, Tarik; Elkhader, Khalid; Koutani, Abdellatif; Andaloussi, Ahmed Ibn attya

2014-01-01

La fistule colo-vésicale sur une hydatidose sigmoidienne est une entité pathologique exceptionnelle. Nous rapportions une nouvelle observation, ou seront rappelées les principales données diagnostique et thérapeutique de cette affection. PMID:25722790

Professionnalisation ou Deprofessionnalisation: Une Base Conceptuelle pour L'evaluation de La Competence en Psychologie.

ERIC Educational Resources Information Center

Perron, Jacques; And Others

1980-01-01

Elements of professionalization--systematic body of theory, social recognition, monopoly, and degree of organization--are presented and applied to the development of professional psychology in Quebec. The concept of deprofessionalization is introduced as an alternative basis for evaluating competence in professional psychology. (Author)

PCE/TCE DEGRADATION USING MULCH BIOWALLS

EPA Science Inventory

A passive reactive barrier (Biowall) was installed at the OU-1 site at Altus Air Force Base, Oklahoma to treat TCE contamination in ground water from a landfill. Depth to ground water varies from 1.8 to 2.4 meters below land surface. To intercept and treat the plume of contamin...

A Tracer Test to Characterize Treatment of TCE in a Permeable Reactive Barrier

EPA Science Inventory

A tracer test was conducted to characterize the flow of ground water surrounding a permeable reactive barrier constructed with plant mulch (a biowall) at the OU-1 site on Altus Air Force Base, Oklahoma. This biowall is intended to intercept and treat ground water contaminated by ...

Permitting of Landfill Bioreactor Operations: Ten Years after the RD&D Rule

EPA Science Inventory

Prior to promulgation of the Rule, there were approximately 20 full-scale bioreactor projects in North America, including one in Canada. Of these, six were permitted by EPA (four Project XL sites and two projects listed separately under a cooperative research agreement at the Ou...

Pour Savoir ou vous en etes. Evaluez vous-meme vos connaissances (Knowing Where You Are. Evaluate Your Knowledge by Yourself).

ERIC Educational Resources Information Center

Aiello, Angelo; And Others

1986-01-01

A form is presented for language teacher self-evaluation concerning attitudes and knowledge about learning theories, general linguistics, sociolinguistics, pragmatics, discourse analysis, teaching methodology, the communicative approach, class activities, class management, instructional support, and evaluation. (MSE)

DIAMOND ALKALI OU2 - PASSAIC RIVER STUDY AREA Conceptual Site Model-Empirical Mass Balance (CSM-EMB)

EPA Science Inventory

EPA, the U.S. Army Corps of Engineers (Corps), New Jersey Department of Transportation (NJDOT) ), National Oceanic and Atmospheric Administration (NOAA), U.S. Fish and Wildlife Service (USFWS) and New Jersey Department of Environmental Protection (NJDEP) are conducting a joint st...

U.S. EPA, Pesticide Product Label, , 05/26/1993

EPA Pesticide Factsheets

2011-04-14

... hOU,. of n,..t tr •• tm.nt If n .. ~It'rl.To .. du ... ,"1.011110';. 'horough'y 'proy Ih. In'm.r. b.dd"'g end ~tf';., r,.:'niJ .ren u"~~h •• urf.e.', .lIghlly mof ... Tr.IJ ..... ...

Area-wide management of Aedes albopictus: lessons learned.

USDA-ARS?s Scientific Manuscript database

Aedes albopictus, the Asian tiger mosquito, is the principal vector of chikungunya fever and a critical vector of dengue. This daytime biting pest often causes the majority of service requests from urban and suburban residents in New Jersey and many other states and nations where it has spread. Ou...

Melanges Pedagogiques (Pedagogical Mixture), 1983.

ERIC Educational Resources Information Center

Melanges Pedagogiques, 1983

1983-01-01

The 1983 issue of the journal on second language teaching and learning contains six articles in French. These include the following: "E.A.O.: Expression avec ordinateur (E.A.O.: Computer-Aided Expression)" (Daniele Abe, Michele Cembalo); "Ou suis-je? De la relation apprenant/environnement (Where Am I? On the Learner/Environment…

ARSENIC SORUCE IDENTIFICATION AT THE GROUND WATER-SURFACE WATER INTERACTION ZONE AT A CONTAMINATED SITE

EPA Science Inventory

One of the challenges in assessing the current impact of the discharge of arsenic contaminated ground water into a surface water body is differentiating the arsenic ground-water flux versus dissolution of in-place contaminated sediments. A field investigation has been carried ou...

77 FR 31215 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-25

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Partial Deletion of the... National Oil and Hazardous Substances Pollution Contingency Plan (NCP). This partial deletion pertains to the surface soil, unsaturated subsurface soil, surface water and sediments of Operable Unit (OU) 1...

Advanced Filter Technology.

DTIC Science & Technology

1983-11-01

UNCLASIFIEDF/V 20/68 N ENS 1~*28 1225 111131.2 III12.2 L-0II 111111. MICROCOP RESOLUTION TEST CHART NAONAL HL’IAU OU 1ANPAPP 𔃾-0 November, 1983...half-waveplates do not have Adequate wide field response to accommodate it, hence the need for compound waveplates. The compound waveplates are

Sustainability of TCE Removal in the Mulch Biowalls at Altus AFB

EPA Science Inventory

A permeable mulch biowall was installed in June 2002 at Landfill 3 (LF-03), Operable Unit 1 (OU-1), Altus AFB, Oklahoma. The demonstration was conducted by Parsons for the AFCEE Technology Transfer Outreach Office. The biowall is approximately 455 feet long, by 24 feet deep, by...

Nitrogen competition between corn and weeds in soils under organic and conventional management

USDA-ARS?s Scientific Manuscript database

Cropping systems research has shown that organic systems can have comparable yields to conventional systems at higher weed biomass levels. Higher weed tolerance in organic systems could be due to differences in labile soil organic matter and nitrogen (N) mineralization potential. The objective of ou...

Problem of Questioning

ScienceCinema

None

2017-12-09

Le Prof.Leprince-Ringuet, chercheur sur le plan scientifique, artistique et humain, parle de la remise en question des hommes et la remise en question scientifique fondamentale ou exemplaire- plusieurs personnes prennent la parole p.ex Jeanmairet, Adam, Gregory. Le Prof.Gregory clot la soirée en remerciant le Prof.Leprince-Ringuet

Oklahoma Center for High Energy Physics (OCHEP)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nandi, S; Strauss, M J; Snow, J

2012-02-29

The DOE EPSCoR implementation grant, with the support from the State of Oklahoma and from the three universities, Oklahoma State University, University of Oklahoma and Langston University, resulted in establishing of the Oklahoma Center for High Energy Physics (OCHEP) in 2004. Currently, OCHEP continues to flourish as a vibrant hub for research in experimental and theoretical particle physics and an educational center in the State of Oklahoma. All goals of the original proposal were successfully accomplished. These include foun- dation of a new experimental particle physics group at OSU, the establishment of a Tier 2 computing facility for the Largemore » Hadron Collider (LHC) and Tevatron data analysis at OU and organization of a vital particle physics research center in Oklahoma based on resources of the three universities. OSU has hired two tenure-track faculty members with initial support from the grant funds. Now both positions are supported through OSU budget. This new HEP Experimental Group at OSU has established itself as a full member of the Fermilab D0 Collaboration and LHC ATLAS Experiment and has secured external funds from the DOE and the NSF. These funds currently support 2 graduate students, 1 postdoctoral fellow, and 1 part-time engineer. The grant initiated creation of a Tier 2 computing facility at OU as part of the Southwest Tier 2 facility, and a permanent Research Scientist was hired at OU to maintain and run the facility. Permanent support for this position has now been provided through the OU university budget. OCHEP represents a successful model of cooperation of several universities, providing the establishment of critical mass of manpower, computing and hardware resources. This led to increasing Oklahoma's impact in all areas of HEP, theory, experiment, and computation. The Center personnel are involved in cutting edge research in experimental, theoretical, and computational aspects of High Energy Physics with the research areas ranging from the search for new phenomena at the Fermilab Tevatron and the CERN Large Hadron Collider to theoretical modeling, computer simulation, detector development and testing, and physics analysis. OCHEP faculty members participating on the D0 collaboration at the Fermilab Tevatron and on the ATLAS collaboration at the CERN LHC have made major impact on the Standard Model (SM) Higgs boson search, top quark studies, B physics studies, and measurements of Quantum Chromodynamics (QCD) phenomena. The OCHEP Grid computing facility consists of a large computer cluster which is playing a major role in data analysis and Monte Carlo productions for both the D0 and ATLAS experiments. Theoretical efforts are devoted to new ideas in Higgs bosons physics, extra dimensions, neutrino masses and oscillations, Grand Unified Theories, supersymmetric models, dark matter, and nonperturbative quantum field theory. Theory members are making major contributions to the understanding of phenomena being explored at the Tevatron and the LHC. They have proposed new models for Higgs bosons, and have suggested new signals for extra dimensions, and for the search of supersymmetric particles. During the seven year period when OCHEP was partially funded through the DOE EPSCoR implementation grant, OCHEP members published over 500 refereed journal articles and made over 200 invited presentations at major conferences. The Center is also involved in education and outreach activities by offering summer research programs for high school teachers and college students, and organizing summer workshops for high school teachers, sometimes coordinating with the Quarknet programs at OSU and OU. The details of the Center can be found in http://ochep.phy.okstate.edu.« less

Effects of a remedial system and its operation on volatile organic compound-contaminated ground water, Operable Unit 1, Savage Municipal Well Superfund Site, Milford, New Hampshire, 1998-2004

USGS Publications Warehouse

Harte, Philip T.

2006-01-01

The Savage Municipal Well Superfund site in the Town of Milford, N.H., is underlain by a 0.5-square mile plume of volatile organic compounds (VOCs), mostly tetrachloroethylene (PCE). The plume occurs mostly within a highly transmissive sand and gravel layer, but also extends into underlying till and bedrock. The plume has been divided into two areas called Operable Unit 1 (OU1), which contains the primary source area, and Operable Unit 2 (OU2), which is defined as the extended plume area. PCE concentrations in excess of 100,000 parts per billion (ppb) had been detected in the OU1 area in 1995, indicating a likely Dense Non-Aqueous Phase Liquid (DNAPL) source. In the fall of 1998, the New Hampshire Department of Environmental Services (NHDES) and the U.S. Environmental Protection Agency (USEPA) installed a remedial system in OU1 to contain and capture the dissolved VOC plume. The OU1 remedial system includes a low-permeability barrier wall that encircles the highest detected concentrations of PCE, and a series of injection and extraction wells to contain and remove contaminants. The barrier wall likely penetrates the full thickness of the sand and gravel; in most places, it also penetrates the full thickness of the underlying basal till and sits atop bedrock. Remedial injection and extraction wells have been operating since the spring of 1999 and include a series of interior (inside the barrier wall) injection and extractions wells and exterior (outside the barrier wall) injection and extraction wells. A recharge gallery outside the barrier wall receives the bulk of the treated water and reinjects it into the shallow aquifer. From 1998 to 2004, PCE concentrations decreased by an average of 80 percent at most wells outside the barrier wall. This decrease indicates (1) the barrier wall and interior extraction effectively contained high PCE concentrations inside the wall, (2) other sources of PCE did not appear to be outside of the wall, and (3) ambient ground-water flow in conjunction with the exterior remedial wells effectively remediated most of the dissolved PCE plume outside the wall. The overburden at middle depths (40 to 70 ft below land surface) downgradient from exterior extraction wells showed relatively slow decreases in PCE concentrations compared to other areas outside the barrier wall. Numerical simulation shows extraction caused the formation of a small downgradient slow-velocity zone. Because the ambient ground-water velocities are high (approximately 1 foot per day), temporary termination of extraction at the exterior wells may increase dilution downgradient from the exterior extraction wells. Extraction can also be optimized on the basis of seasonal hydrologic conditions to facilitate exterior well capture from upgradient areas outside of the barrier wall where PCE concentrations are highest. Reductions in concentrations of PCE inside the barrier wall from 1998 to 2003 were minimal near suspected source areas, indicating that the operation of interior remedial wells had not been effective in remediating dissolved PCE or the DNAPL source. Capture of the dissolved PCE plume within the barrier wall by interior extraction wells could be enhanced if operation (injection rates) increased at underutilized interior injection wells, thereby increasing hydraulic gradients.

Transport de paires EPR dans des structures mesoscopiques

NASA Astrophysics Data System (ADS)

Dupont, Emilie

Dans cette these, nous nous sommes particulierement interesses a la propagation de paires EPR1 delocalisees et localisees, et a l'influence d'un supraconducteur sur le transport de ces paires. Apres une introduction de cette etude, ainsi que du cadre scientifique qu'est l'informatique quantique dans lequel elle s'inscrit, nous allons dans le chapitre 1 faire un rappel sur le systeme constitue de deux points quantiques normaux entoures de deux fils supraconducteurs. Cela nous permettra d'introduire une methode de calcul qui sera reutilisee par la suite, et de trouver egalement le courant Josephson produit par ce systeme transforme en SQUID-dc par l'ajout d'une jonction auxiliaire. Le SQUID permet de mesurer l'etat de spin (singulet ou triplet), et peut etre forme a partir d'autres systemes que nous etudierons ensuite. Dans le chapitre 2, nous rappellerons l'etude detaillee d'un intricateur d'Andreev faite par un groupe de Bale. La matrice T, permettant d'obtenir le courant dans les cas ou les electrons sont separes spatialement ou non, sera etudiee en detail afin d'en faire usage au chapitre suivant. Le chapitre 3 est consacre a l'etude de l'influence du bruit sur le fonctionnement de l'intricateur d'Andreev. Ce bruit modifie la forme du courant jusqu'a aboutir a d'autres conditions de fonctionnement de l'intricateur. En effet, le bruit present sur les points quantiques peut perturber le transport des paires EPR par l'intermediaire des degres de liberte. Nous montrerons que, du fait de l'"intrication" entre la charge de la paire et le bruit, la paire est detruite pour des temps longs. Cependant, le resultat le plus important sera que le bruit perturbe plus le transport des paires delocalisees, qui implique une resonance de Breit-Wigner a deux particules. Le transport parasite n'implique pour sa part qu'une resonance de Breit-Wigner a une particule. Dans le chapitre 4, nous reviendrons au systeme constitue de deux points quantiques entoures de deux fils supraconducteurs, mais ici, les deux points quantiques seront aussi supraconducteurs. On obtiendra alors l'hamiltonien effectif de la meme maniere que precedemment ainsi que la forme du courant. Dans le cas ou la tension entre les deux fils est nulle, nous ferons une comparaison avec l'experience et nous verrons que les resultats obtenus sont plus en accord avec celle-ci si on fait l'hypothese de la presence d'un bain, qui va modeliser le bruit sur l'un des fils. Enfin, dans le dernier chapitre, nous utiliserons a la fois un qubit de charge et un qubit de spin entoures par deux fils supraconducteurs. Nous pourrons alors mesurer l'influence du supraconducteur et voir s'il est possible de creer ici des paires d'electrons intriques et d'aboutir a un pendule quantique. 1Il existe des systemes qui produisent des paires de particules ejectees simultanement dans des directions opposees et qui permettent de tester le paradoxe d' Einstein, Podolsky, Rosen. Chaque particule de la paire est dans un etat indetermine. Si on mesure les etats respectifs des deux particules, on obtient systematiquement des resultats complementaires, soit de facon aleatoire: 0-1 ou 1-0. La mecanique quantique explique que les deux particules ainsi produites constituent un seul systeme, une paire EPR.

Photovaporisation prostatique au laser chez les patients à haut risque hémorragique

PubMed Central

Bouabdallah, Zakaria; Kharbouchi, Amine; Colau, Alexandre; Cariou, Gerard

2013-01-01

Introduction Les patients sous traitement anticoagulant sont à risque élevé de saignement lors de la résection transurétrale de la prostate ou de l'adénomectomie par taille vésicale et ils se voient souvent récuser pour la chirurgie de l'hyperplasie bénigne de la prostate symptomatique. En Utilisant la photovaporisation de la prostate, les patients à haut risque peuvent subir en toute sécurité la chirurgie. Nous avons évalué l'innocuité et l'efficacité de la photovaporisation de la prostate (PVP) chez les patients sous anticoagulants en cours avec les dérivés de la coumarine, l'aspirine ou le clopidogrel, se plaignant de symptômes d'hypertrophie bénigne de la prostate. Méthodes Entre janvier 2009 et mai 2010, 47 hommes sous anticoagulation systémique ont subi une photovaporisation de la prostate. Les données ont été recueillies sur les caractéristiques démographiques, les comorbidités, les complications, la natrémie, l'hémoglobine, le débit urinaire maximal, le résidu post-mictionnel, l'IPSS et les complications. Résultats L'âge moyen était de 78 ans, le volume prostatique moyen était de 44g et le PSA était de 3.4ng/ml. Parmi les 10 patients (21.2%) étaient sous AVK, 27 (57.4%) étaient sous aspirine, 2 (4.2%) étaient sous clopidogrel, un sous fondaparinux et 6 (12.7%) étaient sous 2 anticoagulants ou plus. Le score ASA moyen était de 3. La durée moyenne de fonctionnement de l'appareil était de 38 minutes, l'énergie moyenne utilisée était de 200kJ. La durée moyenne d'hospitalisation était de 2 jours. Les complications survenant dans les 30 jours comprenaient une infection urinaire chez 5 patients (10.6%), une dysurie chez 4 patients et une hémorragie retardée chez 4 autres (8.5%). Un seul de ces patients a nécessité une transfusion sanguine et aucun patient n'a nécessité une réintervention. En 3 mois de suivi un seul patient a nécessité une incision du col vésical pour sclérose du col. Aucune incontinence ou sténose urétrale n'a été rapportée. Des améliorations significatives ont été notées dans l'IPSS, le débit urinaire maximal et le résidu post-mictionnel. Conclusion La PVP est caractérisé par d'excellentes propriétés hémostatiques et taux très faible de complications peropératoires même chez les patients sous 2 ou plusieurs agents anticoagulants. Sur la base de nos résultats péri-opératoires, nous recommandons la PVP comme traitement chirurgical de première intention chez les patients à haut risque de hémorragique souffrant de symptômes d'hypertrophie bénigne de la prostate. PMID:24570773

Connaissances et attitudes des relais communautaires sur les fièvres hémorragiques à virus Lassa et Ebola dans le département de la Donga (Nord Bénin)

PubMed Central

Attinsounon, Cossi Angelo; Hounnankan, Cossi Athanase; Dovonou, Comlan Albert; Alassani, Cossi Adébayo; Salifou, Sourakatou

2017-01-01

Introduction L’objectif de cette étude était d’évaluer les connaissances et attitudes des relais communautaires vis-à-vis des fièvres hémorragiques à virus Ebola et Lassa et leur implication dans la mise œuvre des activités de prévention de ces maladies. Méthodes Une enquête transversale descriptive a été menée auprès des relais communautaires recrutés par tirage au sort dans 40 villages du département de la Donga. Ces relais faisaient la prise en charge à domicile des maladies respiratoires, diarrhéiques et du paludisme chez les enfants de moins de cinq ans. Un questionnaire anonyme a été administré par interview directe. Les données ont été analysées à l’aide du logiciel Epi-info 3.5.1. Résultats Au total 58 relais communautaires (RC) ont participé à cette enquête sur les 60 attendus. L’âge moyen était de 38,7±10,6 ans avec un sex-ratio de 3,5. Il y avait majoritairement trente cinq cultivateurs (60,3%) et treize revendeuses (22,4%). Quarante huit enquêtés (82,8%) reconnaissaient les deux maladies comme étant graves, mortelles et transmissibles. Les trois principales voies de transmission citées étaient le contact ou la consommation de gibiers (87,9%), le contact direct avec les personnes infectées (74,1%) ou leurs cadavres (46,6%). Les principaux moyens préventifs énumérés étaient en lien avec les voies de transmission. La fièvre (81,0%), les vomissements (81,0%) et la diarrhée (60,3%) venaient en tête des symptômes cités. Seulement vingt-deux RC (37,9%) disposaient de gants mais les utilisaient rarement pour examiner les enfants malades. Quant à la conduite à tenir devant un cas suspect de fièvre hémorragique virale Lassa ou Ebola, quarante-et-un relais communautaires (70,7%) feraient recours aux agents de santé sans toucher au malade, neuf (15,5%) feraient appel à l’ambulance et huit (13,8%) transporteraient le cas sur leur propre moto ou sur un taxi-moto vers le centre de santé le plus proche. Conclusion Le renforcement des capacités des relais communautaires sur les fièvres hémorragiques virales contribuerait à l’amélioration de leurs connaissances sur ces épidémies mortelles et à la qualité de leurs interventions dans la population. Introduction This study aimed to evaluate the knowledges and attitudes of community volunteers on Lassa and Ebola viral haemorrhagic fevers and their role in the implementation of activities for the prevention of these diseases. Methods We conducted a cross-sectional descriptive survey among community volunteers chosen by lot in 40 villages in the Donga Department. Children under five years of age with respiratory and diarrheal diseases and malaria were treated by these community volunteers in their home. An anonymous questionnaire was administered by direct interview. Data were analyzed using Epi-Info 3.5.1. Results Out of 60 community volunteers potentially participating in this survey a total of 58 effectively participated. The average age of community volunteers was 38.7 ± 10.6 years with a sex-ratio of 3.5. The majority of the community volunteers were farmers (thirty-five, 60.3%) and resellers (thirteen, 22.4%). Forty-eight respondents (82.8%) recognized the two diseases as being serious, life-threatening and transmissible. The three main routes of transmission cited were the contact with or the consumption of bushmeat (87.9%), the direct contact with infected people (74.1%) or with their corpses (46.6%). The main preventive measures listed were related to the routes of transmission. Fever (81.0%), vomiting (81.0%) and diarrhea (60.3%) were at the top of the cited symptoms. Only twenty-two community volunteers (37.9%) had gloves but they rarely used them to examine sick children. As regards the procedure to follow in case of suspected Lassa or Ebola viral haemorrhagic fever , forty-one community volunteers (70.7%) would make use of community-based health workers without touching the patient, nine (15.5%) would call for the ambulance and eight (13.8%) would take the patient to the nearest health center using their own motorcycle or a motorcycle-taxi. Conclusion Strengthening community volunteers’ capacity to manage viral hemorrhagic fevers would contribute to the improvement of their knowledge of these life-threatening epidemics and to the quality of population health interventions. PMID:28690743

FEASIBILITY STUDY REPORT FOR THE 200-ZP-1 GROUNDWATER OPERABLE UNIT

DOE Office of Scientific and Technical Information (OSTI.GOV)

BYRNES ME

2008-07-18

The Hanford Site, managed by the U.S. Department of Energy (DOE), encompasses approximately 1,517 km{sup 2} (586 mi{sup 2}) in the Columbia Basin of south-central Washington State. In 1989, the U.S. Environmental Protection Agency (EPA) placed the 100, 200, 300, and 1100 Areas of the Hanford Site on the 40 Code of Federal Regulations (CFR) 300, 'National Oil and Hazardous Substances Pollution Contingency Plan' National Contingency Plan [NCPD], Appendix B, 'National Priorities List' (NPL), pursuant to the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). The 200 Areas NPL sites consist of the 200 West and 200 Eastmore » Areas (Figure 1-1). The 200 Areas contain waste management facilities, inactive irradiated fuel reprocessing facilities, and the 200 North Area (formerly used for interim storage and staging of irradiated fuel). Several waste sites in the 600 Area, located near the 200 Areas, also are included in the 200 Areas NPL site. The 200 Areas NPL site is in a region referred to as the 'Central Plateau' and consists of approximately 700 waste sites, excluding sites assigned to the tank farm waste management areas (WMAs). The 200-ZP-1 Groundwater Operable Unit (OU) consists of the groundwater located under the northern portion of the 200 West Area. Waste sources that contributed to the 200-ZP-1 OU included cribs and trenches that received liquid and/or solid waste in the past from the Z Plant and T Plant aggregate areas, WMA-T, WMA-TX/TY, and the State-Approved Land Disposal Site (SALDS). This feasibility study (FS) for the 200-ZP-1 Groundwater OU was prepared in accordance with the requirements of CERCLA decision documents. These decision documents are part of the Administrative Record for the selection of remedial actions for each waste site and present the selected remedial actions that are chosen in accordance with CERCLA, as amended by the Superfund Amendments and Reauthorization Act of 1986, and to the extent practicable, the NCP. This FS conforms to the conditions set forth in the Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) (Ecology et al. 2003) and amendments, signed by the Washington State Department of Ecology (Ecology), EPA, and DOE Richland Operations Office (RL). This also includes Tri-Party Agreement Milestone M-015-00C for completing all 200 Area non-tank farm OU pre-Record of Decision (ROD) documents on or before December 31, 2011. This FS supports the final remedy selection for the 200-ZP-1 OU, as described in the Remedial Investigation/Feasibility Study Work Plan for the 200-ZP-1 Groundwater Operable Unit (referred to as the 200-ZP-1 RI/FS work plan) (DOE/RL-2003-55), as agreed upon by RL and EPA. Tri-Party Agreement Milestone M-015-48B required Draft A of the 200-ZP-1 OU FS and proposed plan to be transmitted to EPA by September 30, 2007. As agreed to with EPA in the 200 Area Unit Managers Meeting Groundwater Operable Unit Status (FH-0503130), the baseline risk assessment (BRA) was delayed from inclusion in the remedial investigation (RI) report and is completed and documented in this FS. The Remedial Investigation Report for 200-ZP-1 Groundwater Operable Unit (referred to as the 200-ZP-1 RI report) (DOE/RL-2006-24) included an evaluation of human health and ecological risks and hazards. The RI report identified the radiological and chemical contaminants of potential concern (COPCs) that represent the primary risks to human health and the environment. The complete risk assessment in this FS incorporates additional analytical data from the unconfined aquifer that were obtained during or after preparation of the RI report, particularly for carbon tetrachloride and technetium-99. This FS also includes the initial results from an ongoing study of technetium-99 contamination near WMA-T, the sampling of new wells near the 216-W-LC laundry waste crib and T Plant, updated Hanford vadose zone fate and transport modeling, and groundwater particle-tracking analysis. The purpose of this FS is to develop and evaluate alternatives for remediation of the groundwater in the 200-ZP-1 OU. The alternatives considered provide a range of potential response actions (i.e., no action; institutional controls and monitored natural attenuation [MNA]; and pump-and-treat with MNA, flow-path control, and institutional controls) that are appropriate to address site-specific conditions. The alternatives are evaluated against seven of the nine CERCLA evaluation criteria defined in Guidance for Conducting Remedial Investigations and Feasibility Studies Under CERCLA (EPA/540/G-891004). The remaining two CERCLA criteria will be formally assessed during the public comment period. The FS evaluation serves as the basis for identifying a remedy to mitigate potential risks to human health and the environment. A preferred alternative (or alternatives) will be presented to the public for review and comment in the proposed plan.« less

2011 Mound Site Groundwater Plume Rebound Exercise and Follow-Up - 13440

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hooten, Gwendolyn; Cato, Rebecca; Lupton, Greg

2013-07-01

The Mound Site facility near Miamisburg, Ohio, opened in 1948 to support early atomic weapons programs. It grew into a research, development, and production facility performing work in support of the U.S. Department of Energy (DOE) weapons and energy programs. The plant was in operation until 1995. During the course of operation, an onsite landfill was created. The landfill was located over a finger of a buried valley aquifer, which is a sole drinking water source for much of the Miami Valley. In the 1980's, volatile organic compounds (VOCs) were discovered in groundwater at the Mound site. The site wasmore » placed on the National Priorities List on November 21, 1989. DOE signed a Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) Federal Facility Agreement with the U.S. Environmental Protection Agency (EPA) and the Ohio Environmental Protection Agency. The agreement became effective in October 1990. The area that included the landfill was designated Operational Unit 1 (OU-1). In 1995, a Record of Decision was signed that called for the installation and operation of a pump and treatment (P and T) system in order to prevent the VOCs in OU-1 groundwater from being captured by the onsite water production wells. In addition to the P and T system, a soil vapor extraction (SVE) system was installed in 1997 to accelerate removal of VOCs from groundwater in the OU-1 area. The SVE system was successful in removing large amounts of VOCs and continued to operate until 2007, when the amount of VOCs removed became minimal. A rebound study was started in February 2003 to determine how the groundwater system and contaminants would respond to shutting down the P and T system. The rebound test was stopped in February 2004 because predetermined VOC threshold concentrations were exceeded down-gradient of the landfill. The P and T and SVE systems were restarted after the termination of the rebound test. In 2006, the remediation of the Mound site was completed and the site was declared to be protective of human health and the environment, as long as the institutional controls are observed. The institutional controls that apply to the OU-1 area include provisions that no soil be allowed to leave the site, no wells be installed for drinking water, and the site may be approved only for industrial use. The onsite landfill with the operating CERCLA remedy remained. However, the Mound Development Corporation lobbied Congress for funds to remediate the remaining onsite landfill to allow for property reuse. In 2007 DOE received funding from Congress to perform non-CERCLA removal actions at OU-1 to excavate the site sanitary landfill. In 2009, DOE received American Recovery and Reinvestment Act funding to complete the project. Excavation of the landfill occurred intermittently from 2006 through 2010 and the majority of the VOC source was removed; however, VOC levels near the P and T system remained greater than the EPA maximum contaminant levels (MCLs). Presently, groundwater is contained using two extraction wells to create a hydraulic barrier to prevent down-gradient migration of VOC-impacted groundwater. Since the primary contamination source has been removed, the feasibility of moving away from containment to a more passive remedy, namely monitored natural attenuation (MNA), is being considered. A second rebound study was started in June 2011. If contaminant and groundwater behavior met specific conditions during the study, MNA would be evaluated and considered as a viable alternative for the groundwater in the OU-1 area. From June through December 2011, the second rebound study evaluated the changes in VOC concentrations in groundwater when the P and T system was not in operation. As the study progressed, elevated concentrations of VOCs that exceeded predetermined trigger values were measured along the down-gradient boundary of the study area, and so the P and T system was restarted. It was determined that a discrete area with VOC concentrations greater than the MCLs was present in groundwater down-gradient of the extraction wells. The source was not identified, but the contamination was thought not to be caused by residually contaminated soil beneath the former landfill. The data collected so far supports the consideration of MNA as a viable alternative to hydraulic containment. Additional investigations are being performed to identify possible sources or pathways of VOCs in groundwater that may be contributing to the elevated VOC levels measured down-gradient of the extraction well system. Data from this additional investigation will be used to determine whether the VOCs detected down-gradient of the hydraulic boundary are the result of residual soil contamination, a previously unknown contribution of VOC-contaminated water entering the groundwater outside the capture zone of the extraction wells, or a pulse of VOC-contaminated groundwater from the OU-1 landfill that occurred during the rebound study. (authors)« less

Post operative infections of the spine: technique, indications and results of the surgical treatment - A retrospective study of 90 cases.

PubMed

Lazennec, J Y; Laville, C; Konel, B; Roy-Camille, R; Saillant, G; Poloujadoff, M P

1996-05-01

Post operative infection in spine surgery is a well known complication. The authors studied a series of 90 patients in accordance with an homogenous strategy based on the excision of necrotic and infected tissues, associated with appropriate antibiotics.The results are analyzed according to the degree of infection (which is based on the type of germs and their associations), and type of patients, the delay in diagnosis and the anatomical extension of the infected lesions.Making a difference between superficial and deep infection is of no therapeutic value and may lead to wrong and inadequate treatment.One must separate the common infections (which are due to germs as staphylococcus aureus or others from the urinary or digestive tract), and severe infections (which are either due to a per operative massive and deep contamination, or associated with patient's poor general condition).This series is mainly about posterior approaches to the spine, with or without osteosynthesis. Technical problems for treatment depend on the site of infection, particularly at the thoracic kyphosis level, or at the lumbar level where the muscle necrosis can be extensive. At the cervical level, the infection of an anterior approach mandates a check on the respiratory and digestive tracts.Removing the osteosynthesis is not mandatory in post operative spinal infections, as it may induce severe mechanical destabilization. An anterior approach is not necessarily required in the case of a posterior infection, except with massive contamination of an anterior graft. In some cases, posterior lumbar interbody fusion can lead to the indication for anterior cage removal.Pseudarthrosis of an infected spine, initially treated to obtain fusion, is still the worst complication. In case of previous posterior infection, even a severe one, fusion can still be obtained through a secondary anterior or posterior approach for grafting, with or without osteosynthesis.In this series, there was no neurological complication due to infection.However, eight diceases occured in weak patients with neurological involvement. This points out the importance of the general treatment associated with the surgery, and the necessity of a thorough assessment. a thorough assessment.RéSUMé: Les infections post-opératoires représentent une complication largement documentée dans le domaine de la chirurgie du rachis. Les auteurs étudient une série de 90 patients traités selon une stratégie homogène basée sur l'excision des tissus nécrosés et infectés associée à l'utilisation d'un traitement antibiotique adapté. Les résultats sont analysés en fonction du degré d'infection (basé sur le type de germe et leurs associations) de l'état des patients, du délai pour le diagnostic et de l'étendue anatomique des lésions infectieuses. L'opposition entre infection superficielle et profonde semble sans intérêt sur le plan thérapeutique et peut conduire à un traitement insuffisant ou mal adapté.Il est important de séparer les infections classiques (qui sont dûes à des germes comme le staphylocoque doré ou d'autres germes provenant de la sphère urinaire ou digestive) et les infections sévères (qui sont soit dûes à une contamination per-opératoire massive et profonde ou associées à des patients dont létat général est déficient).Cette série est principalement basée sur les abord postérieurs du rachis avec ou sans ostéosynthèse. Les problèmes techniques pour le traitement dépendent du site de l'infection: aux niveaux thoracique et lombaire, la nécrose musculaire peut être très extensive. Au niveau cervical, l'infection d'un abord antérieur impose de vérifier l'intégrité du tractus aéro-digestif.L'ablation initiale du matériel n'est pas nécessaire dans beaucoup de cas d'infections post-opératoires car elle peut induire des destabilisations sévères et des complications mécaniques supplémentaires. Un abord antérieur n'est pas forcément nécessaire en cas d'infection postérieure mises à part les contaminations massives d'une greffe antérieure ou une infection d'une cage intervertébrale réalisée pour une fusion intersomatique par voie postérieure.La pseudarthrose des greffes sur un rachis infecté qui a été traité initialement pour obtenir une fusion reste encore la plus sévère des complications. Dans les cas d'infections postérieures même sévères, la fusion peut être encore obtenue secondairement grâce à un abord antérieur ultérieur ou même un abord postérieur pour des greffes complémentaires avec ou sans ostéosynthèse.Dans cette série, les auteurs ne signalent aucune complication neurologique dûe à l'infection. Néanmoins, 8 décès sont à déplorer chez des patients fragiles avec signes neurologiques initiaux. Ceci souligne l'importance du traitement général associé à la chirurgie et la nécessité d'un bilan complet de ces malades.

Acute Ethanol Intake Induces NAD(P)H Oxidase Activation and Rhoa Translocation in Resistance Arteries.

PubMed

Simplicio, Janaina A; Hipólito, Ulisses Vilela; Vale, Gabriel Tavares do; Callera, Glaucia Elena; Pereira, Camila André; Touyz, Rhian M; Tostes, Rita de Cássia; Tirapelli, Carlos R

2016-11-01

The mechanism underlying the vascular dysfunction induced by ethanol is not totally understood. Identification of biochemical/molecular mechanisms that could explain such effects is warranted. To investigate whether acute ethanol intake activates the vascular RhoA/Rho kinase pathway in resistance arteries and the role of NAD(P)H oxidase-derived reactive oxygen species (ROS) on such response. We also evaluated the requirement of p47phox translocation for ethanol-induced NAD(P)H oxidase activation. Male Wistar rats were orally treated with ethanol (1g/kg, p.o. gavage) or water (control). Some rats were treated with vitamin C (250 mg/kg, p.o. gavage, 5 days) before administration of water or ethanol. The mesenteric arterial bed (MAB) was collected 30 min after ethanol administration. Vitamin C prevented ethanol-induced increase in superoxide anion (O2-) generation and lipoperoxidation in the MAB. Catalase and superoxide dismutase activities and the reduced glutathione, nitrate and hydrogen peroxide (H2O2) levels were not affected by ethanol. Vitamin C and 4-methylpyrazole prevented the increase on O2- generation induced by ethanol in cultured MAB vascular smooth muscle cells. Ethanol had no effect on phosphorylation levels of protein kinase B (Akt) and eNOS (Ser1177 or Thr495 residues) or MAB vascular reactivity. Vitamin C prevented ethanol-induced increase in the membrane: cytosol fraction ratio of p47phox and RhoA expression in the rat MAB. Acute ethanol intake induces activation of the RhoA/Rho kinase pathway by a mechanism that involves ROS generation. In resistance arteries, ethanol activates NAD(P)H oxidase by inducing p47phox translocation by a redox-sensitive mechanism. O mecanismo da disfunção vascular induzido pelo consumo de etanol não é totalmente compreendido. Justifica-se, assim a identificação de mecanismos bioquímicos e moleculares que poderiam explicar tais efeitos. Investigar se a ingestão aguda de etanol ativa a via vascular RhoA/Rho quinase em artérias de resistência e o papel das espécies reativas de oxigênio (ERO) derivadas da NAD(P)H oxidase nessa resposta. Nós também avaliamos se ocorreu translocação da p47phox e ativação da NAD(P)H oxidase após o consumo agudo de etanol. Ratos Wistar machos foram tratados com etanol via oral (1g/kg, p.o. gavagem) ou água (controle). Alguns ratos foram tratados com vitamina C (250 mg/kg, p.o. gavagem, 5 dias) antes de água ou etanol. O leito arterial mesentérico (LAM) foi coleado 30 min após a administração de etanol. A vitamina C preveniu o aumento da geração de ânion superóxido (O2 -) e lipoperoxidação no LAM induzidos pelo etanol. A atividade da catalase (CAT), da superóxido dismutase (SOD) e os níveis de glutationa reduzida(GSH), nitrato e peróxido de hidrogênio (H2O2) não foram afetados após a ingestão aguda de etanol. A vitamina C e o 4-metilpirazol preveniram o aumento na geração de O2 - induzido pelo etanol em cultura de células do músculo liso vascular (CMLV). O etanol não afetou a fosforilação da proteína quinase B (Akt) e nem da óxido nítrico sintase endotelial (eNOS) (nos resíduos de Ser1177 ou Thr495) ou a reatividade vascular do LAM. A vitamina C preveniu o aumento da razão membrana:citosol da p47phox e a expressão da RhoA no LAM de rato induzido pelo etanol. A ingestão aguda de etanol induz a ativação da via RhoA/Rho quinase por um mecanismo que envolve a geração de ERO. Nas artérias de resistência, o etanol ativa NAD(P)H oxidase induzindo a translocação da p47phox por um mecanismo redox-sensível.

Physicochemical and bacteriological characterization of raw sewage from the Meknes region Morocco

NASA Astrophysics Data System (ADS)

Hassan, Ouallal; Hamzaoui Najia, El; Mohammed, Sbiti; Mohammed, Machkor; Lahcen, Messaoudi; Mohamed, Azrour

2018-05-01

The region of Meknes suffers from a significant delay in the water sector, including sewage treatment. The Urban waste water in the region originates from various activities; households, industry, agriculture and hospital. These waters are released in to nature without any treatment, which constitutes a serious risk for the environment. The objective of this research is to characterize the physicochemical and bacteriological pollution of the three sewage collectors of the Meknes region (Aïn Choubbik, Oued Ouislane and Aïn Taoujdate). Indeed, the pollution parameters; biological and chemical oxygen demand are abnormally high, which indicates clearly that waste waters is rich of reducing or oxidizing organic materials. Ammonium, nitrogen, phosphorus and heavy metals concentrations exceed the limit values. So these waters are classified as bad or very bad quality. On the one hand, the presence of a large bacterial load indicates fecal contamination. The total coliform, fecal coliform and fecal streptococci levels are high exceeding exceed the values specified the WHO guidelines and the Moroccan standards. This situation is likely to cause serious and irreparable damage to the environment groundwater. To counter this, make the necessary investment in sewage treatment and other remedial measures is key to preventing pollution and its spread.

L'astronomie au féminin

NASA Astrophysics Data System (ADS)

Nazé, Yaël

2006-03-01

Qui détient le record des découvertes de comètes ? Une femme. Qui a permis de comprendre comment est organisée la population des étoiles ? Une femme. Qui a découvert la loi permettant d'arpenter l'Univers, a trouvé des phares dans l'espace, a compris le fonctionnement des forges stellaires et a bouleversé notre vision de l'Univers ? Encore et toujours une femme... Pourtant, quand on doit citer un astronome -- historique -- au hasard, on pense le plus souvent -- des hommes : Ptolémée, Galilée, Copernic ou, plus près de nous par exemple, Hubble. Certes, au cours des siècles, les femmes n'ont guère eu accès aux sciences en général et -- l'astronomie en particulier mais ce n'est pas une raison pour croire en l'absence totale de contributions dues au beau sexe ! C'est ce que dévoile ici l'auteur. Loin de toute forme de féminisme enragé, on suivra le parcours de quelques scientifiques importantes qui ont par hasard en commun une même particularité : leur sexe.

Metabolic syndrome and quality of life: a systematic review.

PubMed

Saboya, Patrícia Pozas; Bodanese, Luiz Carlos; Zimmermann, Paulo Roberto; Gustavo, Andréia da Silva; Assumpção, Caroline Melo; Londero, Fernanda

2016-11-28

to present currently available evidence to verify the association between metabolic syndrome and quality of life. Cochrane Library, EMBASE, Medline and LILACS databases were studied for all studies investigating the association with metabolic syndrome and quality of life. Two blinded reviewers extracted data and one more was chosen in case of doubt. a total of 30 studies were included, considering inclusion and exclusion criteria, which involved 62.063 patients. Almost all studies suggested that metabolic syndrome is significantly associated with impaired quality of life. Some, however, found association only in women, or only if associated with depression or Body Mass Index. Merely one study did not find association after adjusted for confounding factors. although there are a few studies available about the relationship between metabolic syndrome and quality of life, a growing body of evidence has shown significant association between metabolic syndrome and the worsening of quality of life. However, it is necessary to carry out further longitudinal studies to confirm this association and verify whether this relationship is linear, or only an association factor. apresentar as evidências disponíveis atuais para verificar a associação entre síndrome metabólica e qualidade de vida. Cochrane Library, EMBASE, Medline e LILACS foram as bases de dados consultadas na identificação de todos os estudos que investigavam a associação entre síndrome metabólica e qualidade de vida. Dois revisores de forma independente e cegados extraíram os dados e, em caso de dúvidas, um outro revisor foi escolhido. um total de 30 estudos foram incluídos, considerando os critérios de inclusão e exclusão, os quais envolveram 62.063 pacientes. A maioria dos estudos sugerem que a síndrome metabólica é significativamente associada à piora da qualidade de vida. Alguns, no entanto, demonstram associação apenas em mulheres, ou somente se associadas à depressão ou índice de massa corporal. Entretanto, um estudo não demonstrou tal associação, após ajuste para os fatores confundidores. apesar de dispormos de poucos estudos a respeito da relação entre síndrome metabólica e qualidade de vida, um número crescente de evidências tem demonstrado uma significativa associação entre a síndrome metabólica e o prejuízo na qualidade de vida. Entretanto, é necessário que sejam conduzidos estudos longitudinais com objetivo de confirmar esta associação e, determinar se esta relação é linear ou somente um fator de associação. presentar las evidencias actualmente disponibles para verificar la asociación entre el síndrome metabólico y la calidad de vida. se consultaron las bases de datos Cochrane Library, EMBASE, Medline y LILACS para la identificación de todos los estudios que investigaban la asociación entre síndrome metabólico y calidad de vida. Dos revisores de tipo ciego extrajeron los datos y en caso de dudas se eligió un revisor adicional. un total de 30 estudios fueron incluidos, llevando en consideración los criterios de inclusión y exclusión, totalizando 62.063 pacientes. La mayoría de los estudios sugieren que el síndrome metabólico esta significativamente asociado al empeoramiento de la calidad de vida. Algunos, sin embargo muestran asociación solamente en mujeres, o sólo asociados a depresión o índice de masa corporal. También un estudio no mostró esta asociación después de ajustar por los factores confundentes. a pesar de tener a disposición pocos estudios en referencia a la relación entre síndrome metabólico y calidad de vida, un número creciente de evidencias ha demostrado una asociación significativa entre síndrome metabólico y perjuicio de la calidad de vida. Sin embargo es necesario que se realicen estudios longitudinales con el objetivo de confirmar esta asociación y determinar si esta relación es linear o solamente un factor de asociación.

Working with Disciplinary Artifacts: An Introductory Writing Studies Course for Writing Majors

ERIC Educational Resources Information Center

Ostergaard, Lori

2015-01-01

WRT 329: Introduction to Writing Studies is a course in Oakland University's (OU) Writing and Rhetoric major program that provides students with a survey of composition studies as an academic discipline. It includes an examination of the history, theories, research, curricula, and pedagogies associated with composition studies in the university.…

RATE OF TCE DEGRADATION IN A PLANT MULCH PASSIVE REACTIVE BARRIER (BIOWALL)

EPA Science Inventory

A passive reactive barrier was installed at the OU-1 site at Altus Air Force Base, Oklahoma to treat TCE contamination in ground water from a landfill. Depth to ground water varies from 1.8 to 2.4 meters below land surface. To intercept and treat the plume of contaminated groun...

Cataract surgery in juvenile xanthogranuloma: case report and a brief review of literature.

PubMed

Muralidhar, R; Jain, Ashish; Vijayalakshmi, P; Suparna, G; Santhi, R; Shetty, Shashikanth

2013-11-01

There is limited literature on the management of cataracts in juvenile xanthogranuloma (JXG). A 2-month-old girl presented to us with hyphema, secondary glaucoma OU and skin nodules suggestive of JXG. She developed bilateral cataracts during her follow-up and was treated successfully with cataract surgery and aphakic rehabilitation.

Access to Higher Education: Students with Disabilities at the Open University. Working Together?

ERIC Educational Resources Information Center

Child, Derek

Services to students with disabilities at the Open University (OU) in Great Britain are described. This large distance teaching institution offers courses in multi-media form, using printed texts, audio and video material, radio and television programs, microcomputer software, and tutorial support (available either from local study centers or at…

Literature Review: Cognitive Effects of Thermal Strain

DTIC Science & Technology

2005-02-08

001/TOR Call up No. 7879 -05 On behalf of DEPARTMENT OF NATIONAL DEFENCE Defence Research and Development Canada – Toronto 1133 Sheppard...opérations de lutte contre l’incendie ou les opérations militaires. Humansystems® Incorporated Thermal Strain Literature Review Page vi Table of... VI LIST OF TABLES AND FIGURES

General Education Development (GED®) Credential Attainment, Externalizing Disorders, and Substance Use Disorders in Disconnected Emerging Adults

ERIC Educational Resources Information Center

Bergman, Andrea; Kong, Grace; Pope, Alice

2014-01-01

There are many benefits for emerging adults, both financial and personal, in obtaining a General Education Development (GED®) credential (Ou, 2008). However, little is known about the correlates of GED® credential attainment in "disconnected" emerging adults attending GED® programs. Our goal was to examine whether externalizing…

Reversing the Trend of Engineering Enrollment Declines with Innovative Outreach, Recruiting, and Retention Programs

ERIC Educational Resources Information Center

Davis, C. E.; Yeary, M. B.; Sluss, J. J., Jr.

2012-01-01

This paper discusses an all-encompassing approach to increase the number of students in engineering through innovative outreach, recruiting, and retention programs. Prior to adopting these programs, the School of Electrical and Computer Engineering (ECE) at the University of Oklahoma (OU), Norman, experienced a reduction in engineering enrollment…

Transgene movement in commercial alfalfa seed production: Implications for seed purity

USDA-ARS?s Scientific Manuscript database

The United States is a major exporter of alfalfa seed and hay and the organic dairy industry is one of the fastest growing agricultural sectors. With the advent of genetically-engineered (GE) alfalfa concerns have risen regarding the coexistence of GE and non GE alfalfa since the crop is largely ou...

The Closing of the U.S. Open University

ERIC Educational Resources Information Center

Meyer, Katrina A.

2006-01-01

In spring 1999, the Open University (OU) of the United Kingdom created the U.S. Open University (USOU) to coincide with the explosive growth of online education in the United States. The institution's first chancellor, Richard S. Jarvis (previously chancellor of the University and Community College System of Nevada), began hiring U.S. staff and…

"Sticks and Stones": Masculinities and Conflict Spaces

ERIC Educational Resources Information Center

Tucker, Leigh Adams; Govender, Kaymarlin

2017-01-01

Drawing upon a post-structural ethnography of boys' constructions of gendered and sexual identities in one South African high school, this paper empirically seeks to theorise how 20 Grade 8 boys, identified as The Jokers, The Achievers, The Outcasts and The Average Ou's, simultaneously seek out spaces in male peer culture to cultivate, police and…

Education Relative a l'Environnement: Regards, Recherches, Reflexions. Volume 4.

ERIC Educational Resources Information Center

2003

This document takes a critical look at the relationship between environment, culture, and development from the perspective of education relative to the environment. Papers include: (1) "Education a l'environnement ou acculturation?" (Jean-Etienne Bidou); (2) "Environnement et developpement: La culture de la filiere ONU" (Lucie Sauve, Tom Berryman,…

STABLE ISOTOPE SIGNATURES OF MUCUS OF STEELHEAD TROUT IN A CONTROLLED DIET SWITCH EXPERIMENT

EPA Science Inventory

Our work has shown that fish mucus can serve as a very rapid indicator of diet switching in fish. We performed diet switching studies of steelhead trout in a controlled hatchery setting using specially formulated low delta 15N signature and high delta 15N signature diets. To ou...

Development of a statewide transportation data warehousing and mining system under the Louisiana Transportation Information System (LATIS) Program.

DOT National Transportation Integrated Search

2009-04-01

The objectives of this study are to assess whether introducing a data warehousing/data mining system in Louisiana would be feasible and beneficial. The study sets out to identify the features of the most suitable system for the state as well as to ou...

User Need Satisfaction as a Basis for Tactical Airlift Scheduling.

DTIC Science & Technology

1984-03-01

Yr.. Mo.. Day) 1S. PAGE COUNT MS Thesis FROM _ TO 1984 March 220 16. SUPPLEMENTARY NOTATION gym . Daan for Resoarch and Prolusloud ou -t, :... e...SUBROUTINE ROUTE. IT DOES THIS BY TESTING EACH MISSION C- FOR SCHEDULING CONFI ICTS . IF THE NUMBER OF EXPECTED C- CONFLICTS EXCEEDS A MINIMUM VALUE, THE

Pilot study of mold population inside and outside of Puerto Rican residences

EPA Science Inventory

Abstract: Puerto Rico has the highest asthma prevalence in the US. In the states, mold exposures have been linked to the development and exacerbation of asthma. For a pilot study of mold populations in Puerto Rico, dust and air samples were collected in January 2013 inside and ou...

Occlusion veineuse rétinienne et syndrome d'hyperviscosité

PubMed Central

Younes, Samar; Abdellaoui, Meriem; Zahir, Fadoua; Benatiya, Idriss A; Tahri, Hicham

2015-01-01

Les occlusions veineuses rétiniennes secondaires aux syndromes d'hyperviscosité sont rares. Plusieurs cas d'occlusion de la veine centrale de la rétine [OVCR] compliquant une hémopathie ont été décrits, principalement au cours des polycythémies primitives ou secondaires, des lymphomes ou des leucémies. A travers cette observation, nous rapportons le cas d'un patient qui présente une OVCR de l’œil droit survenant dans le cadre d'un myélome multiple. La rétinopathie du syndrome d'hyperviscosité est liée au ralentissement circulatoire qui affecte de manière prépondérante le secteur veineux et donne un aspect de rétinopathie de stase bilatérale, avec dilatation et tortuosité de l'ensemble des veines rétiniennes. A un certain degré d'hyperviscosité, une occlusion veineuse véritable peut survenir. Le traitement comprend la réhydratation, phlébotomie, et plasmaphérèse. PMID:25995806

Ulcere de Marjolin: complication redoutable des sequelles de brûlures

PubMed Central

Ouahbi, S.; Droussi, H.; Boukind, S.; Dlimi, M.; Elatiqi, O.K.; Elamrani, M.D.; Benchamkha, Y.; Ettalbi, S.

2013-01-01

Summary L’ulcère de Marjolin désigne la transformation maligne d’une cicatrice de brûlure ou de toute autre plaie ou ulcération chronique. Le type histologique prédominant reste le carcinome épidermoïde, et il est caractérisé par son agressivité locale, des métastases plus fréquentes, un risque de récurrence et une mortalité plus importante que les carcinomes épidermoïdes classiques. Notre travail est une étude rétrospective portant sur 21 cas d’ulcère de Marjolin, colligés au service de chirurgie plastique du CHU Mohammed VI de Marrakech, avec pour but de relever les aspects épidémiologiques, thérapeutiques et évolutifs de cette pathologie. L’amélioration du pronostic nécessite non seulement un diagnostic et un traitement précoce, mais surtout une attitude préventive qui consiste en des greffes cutanées précoces et des soins réguliers de toute cicatrice de brûlure. PMID:24799850

The in-vitro antimicrobial activities of some medicinal plants from Cameroon.

PubMed

Gangoué-Piéboji, J; Pegnyemb, D E; Niyitegeka, D; Nsangou, A; Eze, N; Minyem, C; Mbing, J Ngo; Ngassam, P; Tih, R Ghogomu; Sodengam, B L; Bodo, B

2006-04-01

The antimicrobial activities of 10 plant species (Voacanga africana, Crepis cameroonica, Plagiostyles africana, Crotalaria retusa, Mammea africana, Lophira lanceolata, Ochna afzelii, Ouratea elongata, Ou. flava and Ou. sulcata), each of which is currently used in the traditional medicine of Cameroon, were investigated in vitro. The activities of a methanol extract of each plant were tested, in disc-diffusion assays, against 37 reference or laboratory strains of seven species of microorganism (Staphylococcus aureus, S. epidermidis, Enterococcus hirae, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Candida albicans). The minimal inhibitory concentrations of each extract were then estimated, against each of the more susceptible microorganisms (i.e. those giving an inhibition zone measuring at least 9 mm in diameter in the disc-diffusion assays), by agar dilution. Although, in the disc-diffusion assays, each of the 10 methanol extracts investigated displayed some degree of antimicrobial activity against at least one species of microorganism, no activity against the Gram-negative bacteria (Es. coli, K. pneumoniae and Ps. aeruginosa) was observed. The extract with the greatest antimicrobial activity was that of Pl. africana (Euphorbiaceae).

Superfund Record of Decision (EPA Region 8): Anaconda Smelter site, (Operable Unit 11 - Flue Dust), Deer Lodge County, Anaconda, MT. (Second remedial action), September 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-09-23

The 6,000-acre Anaconda Smelter site is a former copper and ore processing facility in Deer Lodge County, Montana. Land use in the area is predominantly residential. The site is bounded on the north and east, respectively, by the Warm Springs Creek and Mill Creek, both of which are potential sources of drinking water. From 1884 until 1980 when activities ceased, the site was used for ore processing and smelting operations. In 1988, EPA conducted an investigation to determine the nature and extent of the flue dust contamination. A 1988 ROD addressed the Mill Creek Operable Unit (OU15) and documented themore » relocation of residents from the community surrounding the smelter site as the selected remedial action. The Record of Decision (ROD) addresses the Flue Dust Operable Unit (OU11). The primary contaminants of concern affecting this site from the flue dust materials are metals including arsenic, cadmium, and lead. The selected remedial action for the site is included.« less

Modelling soil salinity in Oued El Abid watershed, Morocco

NASA Astrophysics Data System (ADS)

Mouatassime Sabri, El; Boukdir, Ahmed; Karaoui, Ismail; Arioua, Abdelkrim; Messlouhi, Rachid; El Amrani Idrissi, Abdelkhalek

2018-05-01

Soil salinisation is a phenomenon considered to be a real threat to natural resources in semi-arid climates. The phenomenon is controlled by soil (texture, depth, slope etc.), anthropogenic factors (drainage system, irrigation, crops types, etc.), and climate factors. This study was conducted in the watershed of Oued El Abid in the region of Beni Mellal-Khenifra, aimed at localising saline soil using remote sensing and a regression model. The spectral indices were extracted from Landsat imagery (30 m resolution). A linear correlation of electrical conductivity, which was calculated based on soil samples (ECs), and the values extracted based on spectral bands showed a high accuracy with an R2 (Root square) of 0.80. This study proposes a new spectral salinity index using Landsat bands B1 and B4. This hydro-chemical and statistical study, based on a yearlong survey, showed a moderate amount of salinity, which threatens dam water quality. The results present an improved ability to use remote sensing and regression model integration to detect soil salinity with high accuracy and low cost, and permit intervention at an early stage of salinisation.

wHospital: a web-based application with digital signature for drugs dispensing management.

PubMed

Rossi, Lorenzo; Margola, Lorenzo; Manzelli, Vacia; Bandera, Alessandra

2006-01-01

wHospital is the result of an information technology research project, based on the utilization of a web based application for managing the hospital drugs dispensing. Part of wHospital back bone and its key distinguishing characteristic is the adoption of the digital signature system,initially deployed by the Government of Lombardia, a Northern Italy Region, throughout the distribution of smart cards to all the healthcare and hospital staffs. The developed system is a web-based application with a proposed Health Records Digital Signature (HReDS) handshake to comply with the national law and with the Joint Commission International Standards. The prototype application, for a single hospital Operative Unit (OU), has focused on data and process management, related to drug therapy. Following a multi-faceted selection process, the Infective Disease OU of the Hospital in Busto Arsizio, Lombardia, was chosen for the development and prototype implementation. The project lead time, from user requirement analysis to training and deployment was approximately 8 months. This paper highlights the applied project methodology, the system architecture, and the achieved preliminary results.

Complications inattendues de la chirurgie: deux cas de brûlure par plaque de bistouri électrique

PubMed Central

Diop, B.; Sy, A.; Ba, P.A.; MBaye, B.; Wane, Y.; Sarre, S.M.

2016-01-01

Summary Les risques d’accidents électriques sont une réalité dans les blocs opératoires avec le nombre croissant d’équipements électriques, électroniques et de liquides inflammables utilisés. Le bistouri électrique demeure le dispositif le plus utilisé pour son effet électrochirurgical de coagulation ou section tissulaire. Lorsque qu’elle est défectueuse ou mal placée sur une surface réduite de la peau, la plaque du bistouri peut être à l’origine de brûlure cutanée classiquement profonde, de cicatrisation lente. Elle ajoute à l’affection initiale une surmorbidité iatrogène, inattendue, aux conséquences dévastatrices pour le patient, le chirurgien et parfois la structure hospitalière. Nous rapportons deux cas de brûlure cutanée par plaque de bistouri survenue en peropératoire lors de l’utilisation du bistouri électrique en mode monopolaire et discutons les aspects étiologiques, cliniques et préventifs. PMID:28289364

Fiabilité des structures mécaniques adaptatives: effet de la panne des actionneurs ou des capteurs sur la stabilité

NASA Astrophysics Data System (ADS)

Fall, H.; Charon, W.; Kouta, R.

2002-12-01

Ces dernières décennies, des activités significatives dans le monde étaient dirigées autour du contrôle actif. Le but de ces recherches était essentiellement d'améliorer les performances, la fiabilité et la sécurité des systèmes. Notamment dans le cas des structures soumises à des vibrations aléatoires. D'importants travaux ont été consacré à l'utilisation des “matériaux intelligents” comme capteurs et actionneurs. Cette article propose l'analyse de la fiabilité des systèmes mécaniques en étudiant les pannes des actionneurs ou des capteurs. L'effet de ces pannes sur la stabilité et la performance du système y est démontré. Les méthodologies de conception y sont rappelées. Des exemples numériques sont fournis à travers le contrôle d'un panneau sous chargement dynamique pour illustrer la méthode proposée.

Analyse de plomb dans les peintures

NASA Astrophysics Data System (ADS)

Broll, N.; Frezouls, J.-M.

2002-07-01

The analysis of lead in paints was previously used for the characterisation of pigments. In this way, the analysis is able to specify the century of the painting of a work of art. Recently this technique was also used to determine the toxicity of lead paints in building. This paper compared the result of several X-ray fluorescence spectrometer, either wave length/energy dispersion laboratory apparatus or X-ray microtube/radioactive source portable equipment's. L'analyse du plomb dans les peintures a jusqu'à présent été appliquée essentiellement pour caractériser les pigments lors de leur fabrication et pour identifier des rouvres d'art. Récemment cette technique est également utilisée pour déterminer la toxicité des peintures au plomb dans les bâtiments. Nous avons comparé les performances de plusieurs spectromètres de fluorescence X, soit de laboratoire à dispersion en longueur d'onde ou à dispersion en énergie (avec tube à rayonsX), soit portable avec source radioactive ou tube à rayons X.

Mechanisms of Sodium Transport in Plants—Progresses and Challenges

PubMed Central

Keisham, Monika; Mukherjee, Soumya; Bhatla, Satish C.

2018-01-01

Understanding the mechanisms of sodium (Na+) influx, effective compartmentalization, and efflux in higher plants is crucial to manipulate Na+ accumulation and assure the maintenance of low Na+ concentration in the cytosol and, hence, plant tolerance to salt stress. Na+ influx across the plasma membrane in the roots occur mainly via nonselective cation channels (NSCCs). Na+ is compartmentalized into vacuoles by Na+/H+ exchangers (NHXs). Na+ efflux from the plant roots is mediated by the activity of Na+/H+ antiporters catalyzed by the salt overly sensitive 1 (SOS1) protein. In animals, ouabain (OU)-sensitive Na+, K+-ATPase (a P-type ATPase) mediates sodium efflux. The evolution of P-type ATPases in higher plants does not exclude the possibility of sodium efflux mechanisms similar to the Na+, K+-ATPase-dependent mechanisms characteristic of animal cells. Using novel fluorescence imaging and spectrofluorometric methodologies, an OU-sensitive sodium efflux system has recently been reported to be physiologically active in roots. This review summarizes and analyzes the current knowledge on Na+ influx, compartmentalization, and efflux in higher plants in response to salt stress. PMID:29495332

Perinatal and maternal outcomes in planned home and obstetric unit births in women at ‘higher risk’ of complications: secondary analysis of the Birthplace national prospective cohort study

PubMed Central

Li, Y; Townend, J; Rowe, R; Brocklehurst, P; Knight, M; Linsell, L; Macfarlane, A; McCourt, C; Newburn, M; Marlow, N; Pasupathy, D; Redshaw, M; Sandall, J; Silverton, L; Hollowell, J

2015-01-01

Objective To explore and compare perinatal and maternal outcomes in women at ‘higher risk’ of complications planning home versus obstetric unit (OU) birth. Design Prospective cohort study. Setting OUs and planned home births in England. Population 8180 ‘higher risk’ women in the Birthplace cohort. Methods We used Poisson regression to calculate relative risks adjusted for maternal characteristics. Sensitivity analyses explored possible effects of differences in risk between groups and alternative outcome measures. Main outcome measures Composite perinatal outcome measure encompassing ‘intrapartum related mortality and morbidity’ (intrapartum stillbirth, early neonatal death, neonatal encephalopathy, meconium aspiration syndrome, brachial plexus injury, fractured humerus or clavicle) and neonatal admission within 48 hours for more than 48 hours. Two composite maternal outcome measures capturing intrapartum interventions/adverse maternal outcomes and straightforward birth. Results The risk of ‘intrapartum related mortality and morbidity’ or neonatal admission for more than 48 hours was lower in planned home births than planned OU births [adjusted relative risks (RR) 0.50, 95% CI 0.31–0.81]. Adjustment for clinical risk factors did not materially affect this finding. The direction of effect was reversed for the more restricted outcome measure ‘intrapartum related mortality and morbidity’ (RR adjusted for parity 1.92, 95% CI 0.97–3.80). Maternal interventions were lower in planned home births. Conclusions The babies of ‘higher risk’ women who plan birth in an OU appear more likely to be admitted to neonatal care than those whose mothers plan birth at home, but it is unclear if this reflects a real difference in morbidity. Rates of intrapartum related morbidity and mortality did not differ statistically significantly between settings at the 5% level but a larger study would be required to rule out a clinically important difference between the groups. PMID:25603762

L’identification et traitement du trouble panique avec ou sans agoraphobie

PubMed Central

Foldes-Busque, Guillaume; Marchand, André; Landry, Pierre

2007-01-01

RÉSUMÉ OBJECTIF Renseigner les médecins de première ligne au sujet de l’identification précoce, du diagnostic et du traitement du trouble panique avec ou sans agoraphobie (TP/A). QUALITÉ DES DONNÉES Les données et recommandations présentées proviennent d’une recension des écrits scientifiques réalisée via les banques de données PsycLIT, PsyINFO et MEDLINE (1985 à 2006) en utilisant les descripteurs panic disorder, psychotherapy, psychosocial treatment, treatment et pharmacotherapy. Les recommandations formulées par les auteurs s’appuient sur des données probantes provenant d’études d’excellente qualité. Les informations concernant le diagnostic et l’évaluation du TP/A proviennent d’études épidémiologiques récentes, de consensus et d’opinions d’experts. PRINCIPAL MESSAGE Le TP/A est un trouble psychiatrique souvent rencontré en médecine de première ligne, mais il est fréquemment sous-diagnostiqué et sous-traité. L’identification précoce de ce trouble demande une attention particulière aux symptômes médicalement inexpliqués et, le cas échéant, le médecin doit utiliser des questions spécifiques permettant d’identifier d’éventuelles attaques de panique et de cerner leur signification pour le patient. Le traitement de premier choix pour ce trouble est une psychothérapie d’orientation cognitivo-comportementale administrée par un psychologue ou un psychiatre spécialisé. Si de telles ressources ne sont pas disponibles, le médecin peut opter pour un traitement psychopharmacologique. CONCLUSION Les médecins de famille peuvent jouer un rôle central dans l’identification et le traitement des patients souffrant d’un TP/A. PMID:17934032

Soft tissue augmentation around osseointegrated and uncovered dental implants: a systematic review.

PubMed

Bassetti, Renzo G; Stähli, Alexandra; Bassetti, Mario A; Sculean, Anton

2017-01-01

The aim was to compile the current knowledge about the efficacy of different soft tissue correction methods around osseointegrated, already uncovered and/or loaded (OU/L) implants with insufficient soft tissue conditions. Procedures to increase peri-implant keratinized mucosa (KM) width and/or soft tissue volume were considered. Screening of two databases: MEDLINE (PubMed) and EMBASE (OVID), and manual search of articles were performed. Human studies reporting on soft tissue augmentation/correction methods around OU/L implants up to June 30, 2016, were considered. Quality assessment of selected full-text articles to weight risk of bias was performed using the Cochrane collaboration's tool. Overall, four randomized controlled trials (risk of bias = high/low) and five prospective studies (risk of bias = high) were included. Depending on the surgical techniques and graft materials, the enlargement of keratinized tissue (KT) ranged between 1.15 ± 0.81 and 2.57 ± 0.50 mm. The apically positioned partial thickness flap (APPTF), in combination with a free gingival graft (FGG), a subepithelial connective tissue graft (SCTG), or a xenogeneic graft material (XCM) were most effective. A coronally advanced flap (CAF) combined with SCTG in three, combined with allogenic graft materials (AMDA) in one, and a split thickness flap (STF) combined with SCTG in another study showed mean soft tissue recession coverage rates from 28 to 96.3 %. STF combined with XCM failed to improve peri-implant soft tissue coverage. The three APPTF-techniques combined with FGG, SCTG, or XCM achieved comparable enlargements of peri-implant KT. Further, both STF and CAF, both in combination with SCTG, are equivalent regarding recession coverage rates. STF + XCM and CAF + AMDA did not reach significant coverage. In case of soft tissue deficiency around OU/L dental implants, the selection of both an appropriate surgical technique and a suitable soft tissue graft material is of utmost clinical relevance.

L’ostéotomie de Chiari dans la prise en charge de la dysplasie de la hanche chez l’adulte: à propos de 9 cas

PubMed Central

Shimi, Mohammed; Mahdane, Hicham; Mechchat, Atif; El Ibrahimi, Abedelhalim; El Mrini, Abedelmajid

2013-01-01

La dysplasie acétabulaire de l’adulte jeune entraîne, dans plus de 50% des cas, une coxarthrose secondaire avant l’âge de 50 ans, l’ostéotomie de CHIARI a été décrite initialement dans le traitement de la dysplasie acétabulaire de l’enfant et de l’adolescent, elle a vu ses indications s’étendre à la dysplasie acétabulaire de l’adulte. Nous avons réalisé 9 ostéotomies de CHIARI de 2009 à 2012. Les 9 hanches ont été évaluées cliniquement et radiologiquement en préopératoire et en postopératoire, avec un recul moyen de 18.4 mois. L’ostéotomie a été réalisée sur des hanches douloureuses dysplasiques, sans arthrose (45%) ou avec une arthrose peu évoluée (stade 2: 11%) ou évoluée (stade 3 et 4: 44%). Les résultats fonctionnels ont été très satisfaisants au dernier recul. En effet, le score PMA au dernier recul était de 17.4 en moyenne, avec en particulier, une action antalgique remarquable. Radiologiquement, l’ostéotomie a normalisé pratiquement dans tous les cas la coxométrie, grâce à une médialisation importante habituellement supérieure à 20 mm (87.5%). L’ostéotomie de CHIARI est une intervention sûre. Si l’indication est correctement posée, elle soulage remarquablement les patients et stoppe l’arthrose. Elle garde donc une place privilégiée dans le traitement de la coxarthrose même évoluée sur dysplasie acétabulaire pure ou mixte. PMID:23565312

Remedial investigation/feasibility study for the Clinch River/Poplar Creek operable unit. Volume 3. Appendix E

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-09-01

This document contains Appendix E: Toxicity Information and Uncertainty Analysis, description of methods, from the combined Remedial Investigation/Feasibility Study Report for the Clinch River/Poplar Crack (CR/PC) Operable Unit (OU). The CR/PC OU is located in Anderson and Roane Counties, Tennessee and consists of the Clinch River and several of its embayments in Melton Hill and Watts Bar Reservoirs. These waters have received hazardous substances released over a period of 50 years from the US Department of Energy`s Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensive Environmental Response, Compensation, and Liability Act. A remedial investigation hasmore » been conducted to determine the current nature and extent of any contamination and to assess the resulting risk to human health and the environment. The feasibility study evaluates remedial action alternatives to identify any that are feasible for implementation and that would effectively reduce risk. Historical studies had indicated that current problems would likely include {sup 137}Cs in sediment of the Clinch River, mercury in sediment and fish of Poplar Creek and PCBs and pesticides in fish from throughout the OU. Peak releases of mercury and {sup 137}Cs occurred over 35 years ago, and current releases are low. Past releases of PCBs from the ORR are poorly quantified, and current releases are difficult to quantify because levels are so low. The site characterization focused on contaminants in surface water, sediment, and biota. Contaminants in surface water were all found to be below Ambient Water Quality Criteria. Other findings included the following: elevated metals including cesium 137 and mercury in McCoy Branch sediments; PCBs and chlordane elevated in several fish species, presenting the only major human health risk, significant ecological risks in Poplar Creek but not in the Clinch River.« less

Remedial investigation/feasibility study for the Clinch River/Poplar Creek operable unit. Volume 4. Appendix F

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-09-01

This section contains ecotoxicological profiles for the COPECs for the combined Remedial Investigation/Feasibility Study Report for the Clinch River/Poplar Crack (CR/PC) Operable Unit (OU). The ecotoxicological information is presented for only those endpoints for which the chemicals are COPECs. The CR/PC OU is located in Anderson and Roane Counties, Tennessee and consists of the Clinch River and several of its embayments in Melton Hill and Watts Bar Reservoirs. These waters have received hazardous substances released over a period of 50 years from the US Department of Energy`s Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensivemore » Environmental Response, Compensation, and Liability Act. A remedial investigation has been conducted to determine the current nature and extent of any contamination and to assess the resulting risk to human health and the environment. The feasibility study evaluates remedial action alternatives to identify any that are feasible for implementation and that would effectively reduce risk. Historical studies had indicated that current problems would likely include {sup 137}Cs in sediment of the Clinch River, mercury in sediment and fish of Poplar Creek and PCBs and pesticides in fish from throughout the OU. Peak releases of mercury and {sup 137}Cs occurred over 35 years ago, and current releases are low. Past releases of PCBs from the ORR are poorly quantified, and current releases are difficult to quantify because levels are so low. The site characterization focused on contaminants in surface water, sediment, and biota. Contaminants in surface water were all found to be below Ambient Water Quality Criteria. Other findings included the following: elevated metals including cesium 137 and mercury in McCoy Branch sediments; PCBs and chlordane elevated in several fish species, presenting the only major human health risk, significant ecological risks in Poplar Creek but not in the Clinch River.« less

Ore deposits and epithermal evidences associated with intra-magmatic faults at Aïn El Araâr-Oued Belif ring structure (NW of Tunisia)

NASA Astrophysics Data System (ADS)

Aissa, Wiem Ben; Aissa, Lassaâd Ben; Amara, Abdesslem Ben Haj; Tlig, Said; Alouani, Rabah

2017-03-01

Hydrothermal ore deposits at Aïn El Araâr-Oued Belif location are classified as epithermal deposits type. The ore bodies are hosted by upper Turonian (8-9 M.y) volcanic rhyodacitic complex. Polymetallic sulfide orebodies are mainly concentrated within intra-magmatic faults. Petrographic, XRD, and TEM-STEM investigations revealed that ore minerals are essentially, arsenopyrite, pyrite, chalcopyrite, pyrrhotite, hematite, goethite and magnetite with Au, Ag and Pt trace metals. Gangue minerals are mainly adularia, quartz, sericite, alunite, tridymite, chlorite, phlogopite and smectite. Epithermal alteration is well zoned with four successive characteristic zones: (1) zone of quartz-adularia-sericite and rare alunite; (2) zone of kaolinite and plagioclase albitization; (3) intermediate zone of illite-sericite; (4) sapropelic alteration type zone of chlorite-smectite and rare illite. This can be interpreted as a telescoping of two different acidity epithermal phases; low sulfidation (adularia-sericite) and high sulfidation (quartz-alunite), separated in time or due to a gradual increase of fluids acidity and oxicity within the same mineralization phase. Brecciated macroscopic facies with fragments hosting quartz-adularia-sericite minerals (low-sulfidation phase) without alunite, support the last hypothesis. Geodynamic context and mineral alteration patterns are closely similar to those of Maria Josefa gold mine at SE of Spain which exhibit a volcanic-hosted epithermal ore deposit in a similar vein system, within rhyolitic ignimbrites, altered to an argillic assemblage (illite-sericite abundant and subordinate kaolinite) that grades outwards into propylitic alteration (Sanger-von Oepen et al. (1990)). Mineralogical and lithologic study undertaken in the volcanic host rock at Aïn El Araâr-Oued Belif reveals a typical epithermal low-sulfidation and high-sulfidation ore deposits with dominance of low-sulfidation. Host rocks in these systems range from silicic to intermediate for adularia-sericite type (low sulfidation) to rhyodacite for quartz-alunite type (high sulfidation).

Electrotechnical prospects for superconducting applications

NASA Astrophysics Data System (ADS)

Brunet, Y.; Renard, M.

After a review of the classical limitations, due to iron and copper losses, we give the necessary superconducting properties, needed to achieve significant progresses, either in the size, or in the efficiency of electrotechnical plants. The successive achievement in SC will be explained, in relation with the physics of usual SC, and the needed properties for technology. The problems encountered in electrotechnics by decreasing interest are : networks losses and stability, storage of energy production, transformation and protection. In each case, SC solutions may be found or at least imagined. We shall review the limitations estimated in each case, generally by extrapolation of small scale experiments, with 4 K SC, and try to see what are the modifications which may be obtained by the use of high Tc SC. Special attention will be paid to energy storage and electrical machinery and the interest of completely superconducting plants will be shown. Une fois précisées les limitations actuelles des matériels électriques imposées essentiellement par l'utilisation de matériaux comme le fer ou le cuivre, nous détaillons les caractéristiques des supraconducteurs susceptibles d'améliorer les performances des installations électrotechniques. Les progrès successifs des conducteurs supraconducteurs sont expliqués en tenant compte de leur impact technologique. Les problèmes rencontrés en électrotechnique sont : les pertes et la stabilité des réseaux, le stockage et la production de l'énergie. Dans chaque cas des solutions supraconductrices existent ou peuvent être imaginées. Nous examinons notamment pour les machines électriques et le stockage de l'énergie, les solutions qui existent ou sont en cours de développement avec des supraconducteurs à basse température (˜ 4 K) et quelles sont les modifications apportées par l'utilisation de supraconducteurs à haut Tc.

Stabilization of soils contaminated with explosives and metals from the ammunition demolition activity area and miscellaneous sites at the Umatilla Depot

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lear, P.R.; Gemarr, D.

1997-12-31

The US Army Umatilla Depot (UMD) was established as an ordnance depot in 1941 to store, preserve, and perform minor maintenance on conventional and chemical munitions. From the 1940`s until the present, UMD operated periodically at the 32 miscellaneous sites identified as OU-5. OU-4 consists of twenty sites within the Ammunition Demolition Activity Area. Typical activities conducted at these sites consisted of operations to burn, detonate, and otherwise dispose of ordnance, munitions casings, and other solids wastes. Five sites were selected for remedial action. The remediation contaminants of concern for the sites encompassed both metallic and non-metallic elements and bothmore » inorganic and organic compounds. The remedial action selected for the contaminated soil at these sites was stabilization/solidification (S/S). The site remediation activities for the five sites were performed by OHM Remediation Services Corp. (OHM) under the supervision of the US Army Corps of Engineers (USACE) Seattle District. The remedial action included treatability mix design testing, mobilization and field setup, soil excavation and processing, and S/S treatment. Stabilized soil samples were collected as grab samples from the pugmill discharge conveyor at a rate of every 75 tons of soil feed, corresponding to an individual production lot. None of the 437 production lots failed to meet the UCS requirement of 50 psi, however, 31 (7%) of the 437 lots failed for either TCLP-leachable metals or explosives. With one exception, all production lots which failed were due to exceedances of the TCLP-leachable explosives requirements. Of these 30 lots, 22 lots were from the OU-5 metals sites and were not expected to contain significant amounts of explosives. The areas in the landfill corresponding to these lots were excavated and the material reprocessed.« less

Des ballons pour demain

NASA Astrophysics Data System (ADS)

Régipa, R.

A partir d'une théorie sur la détermination des formes et des contraintes globales d'un ballon de révolution, ou s'en rapprochant, une nouvelle famille de ballons a été définie. Les ballons actuels, dits de ``forme naturelle'', sont calculés en général pour une tension circonférencielle nulle. Ainsi, pour une mission donnée, la tension longitudinale et la forme de l'enveloppe sont strictement imposées. Les ballons de la nouvelle génération sont globalement cylindriques et leurs pôles sont réunis par un câble axial, chargé de transmettre une partie des efforts depuis le crochet (pôle inférieur), directement au pôle supérieur. De plus, la zone latérale cylindrique est soumise à un faible champ de tensions circonférencielles. Ainsi, deux paramètres permettent de faire évoluer la distribution des tensions et la forme de l'enveloppe: - la tension du câble de liaison entre pôles (ou la longueur de ce câble) - la tension circonférencielle moyenne désirée (ou le rayon du ballon). On peut donc calculer et réaliser: - soit des ballons de forme adaptée, comme les ballons à fond plat pour le bon fonctionnement des montgolfières infrarouge (projet MIR); - soit des ballons optimisés pour une bonne répartition des contraintes et une meilleure utilisation des matériaux d'enveloppe, pour l'ensemble des programmes stratosphériques. Il s'ensuit une économie sensible des coûts de fabrication, une fiabilité accrue du fonctionnement de ces ballons et une rendement opérationnel bien supérieur, permettant entre autres, d'envisager des vols à très haute altitude en matériaux très légers.

Détention provisoire des jeunes femmes accusées d'avortement clandestin ou d'infanticide au Sénégal

PubMed Central

Soumah, Mohamed Maniboliot; Pemba, Liliane Flore

2012-01-01

Introduction L'activité sexuelle chez les jeunes les expose à un accroissement du risque de contracter des grossesses non désirées. Le recours à l'avortement clandestin avec son corollaire de complications peut entrainer le décès de la jeune femme. Avortement et infanticide sont interdits et sanctionnés par la loi sénégalaise. Comment ces jeunes femmes vivent-elles leur détention? Existe-il des alternatives à la détention pour éviter leur désocialisation? Méthodes Cette étude rétrospective portait sur la maison d'arrêt des femmes de Dakar située à Liberté 6, un quartier de Dakar. Nous avons procédé à des entretiens avec des femmes détenues à la maison d'arrêt des femmes de Dakar et suspectées d'infanticide ou d'avortement clandestin. Résultats Les femmes de notre échantillon ont une moyenne d’âge inférieure à 25 ans avec parmi elles une fille mineure de 16 ans. Nous avons trouvé 18,51% de femmes suspectées d'infanticide ou d'avortement. Dans notre étude 50% des femmes sont originaires de la périphérie et de la banlieue de Dakar et presque 44% proviennent des autres régions du pays. La durée moyenne de détention provisoire est de neuf mois. Conclusion Malgré leur qualification distincte dans le code pénal: l'infanticide est un crime et l'avortement un délit, les femmes suspectées d'avoir commis ces actes sont soumises à de longues détentions préventives. PMID:22937189

Nouvelle approche à la prise en charge des condylomes

PubMed Central

Lopaschuk, Catharine C.

2013-01-01

Résumé Objectif Faire le résumé des anciens et des nouveaux moyens de traitement des verrues génitales ou condylomes et déterminer comment les utiliser de manière appropriée. Sources des données Une recherche documentaire a été effectuée dans les bases de données suivantes: MEDLINE, PubMed, EMBASE, base de données des synthèses systématiques et registre central des études contrôlées de la Collaboration Cochrane (en anglais), ACP Journal Club et Trip. Les bibliographies des articles extraits ont aussi été examinées. Les études cliniques, les articles de révision qualitative, les rapports consensuels et les guides de pratique clinique ont été retenus. Message principal Les verrues symptomatiques sont présentes chez au moins 1 % des personnes âgées entre 15 et 49 ans et on estime que jusqu’à 50 % des gens sont infectés par le virus du papillome humain à un moment donné de leur vie. L’imiquimod et la podophyllotoxine sont 2 nouveaux traitements pour les verrues génitales externes qui sont moins douloureux et peuvent être appliqués par les patients à la maison. De plus, il a été démontré que le vaccin quadrivalent contre le virus du papillome humain est efficace pour prévenir les condylomes et le cancer du col. Les plus anciennes méthodes thérapeutiques ont aussi leur place dans certaines situations, comme les verrues intravaginales, urétrales, anales ou récalcitrantes ou encore pour les patientes enceintes. Conclusion Les nouveaux traitements des verrues génitales externes peuvent réduire la douleur causée par la thérapie et le nombre de visites au cabinet. Les autres méthodes thérapeutiques demeurent utiles dans certaines situations.

Soins primaires aux adultes ayant des déficiences intellectuelles et développementales

PubMed Central

Sullivan, William F.; Diepstra, Heidi; Heng, John; Ally, Shara; Bradley, Elspeth; Casson, Ian; Hennen, Brian; Kelly, Maureen; Korossy, Marika; McNeil, Karen; Abells, Dara; Amaria, Khush; Boyd, Kerry; Gemmill, Meg; Grier, Elizabeth; Kennie-Kaulbach, Natalie; Ketchell, Mackenzie; Ladouceur, Jessica; Lepp, Amanda; Lunsky, Yona; McMillan, Shirley; Niel, Ullanda; Sacks, Samantha; Shea, Sarah; Stringer, Katherine; Sue, Kyle; Witherbee, Sandra

2018-01-01

Résumé Objectif Mettre à jour les Lignes directrices consensuelles canadiennes 2011 en matière de soins primaires aux adultes ayant une déficience développementale. Méthodes Des médecins de famille et d’autres professionnels de la santé expérimentés dans les soins aux personnes ayant des DID ont examiné et synthétisé les récentes connaissances empiriques, d’écosystèmes, expertes et expérientielles. Un système a été conçu pour catégoriser la qualité des recommandations. Recommandations Les adultes ayant des DID sont un groupe hétérogène de patients qui présentent des affections médicales et des facteurs qui influent sur leur santé, qui diffèrent de ceux qui touchent les autres membres de la communauté de par leur nature, leurs manifestations, leur gravité ou leur complexité. Ces personnes nécessitent une approche de soins et des interventions adaptées à leurs besoins. Les présentes lignes directrices offrent des conseils en matière de normes de soins. Nous avons incorporé des références à des outils cliniques et à d’autres ressources pratiques. Les approches de soins décrites ici s’appliquent aussi à d’autres groupes de patients ayant un déficit cognitif ou de la communication, ou d’autres déficits des fonctions adaptatives. Conclusion À titre de fournisseurs de soins de première ligne, les médecins de famille jouent un rôle vital de promotion de la santé et de bien-être auprès des adultes ayant des DID. Ces lignes directrices peuvent les aider à prendre des décisions avec les patients et les aidants naturels. PMID:29650617

Quasi-elastic neutron scattering study of a re-entrant side-chain liquid-crystal polyacrylate

NASA Astrophysics Data System (ADS)

Benguigui, L.; Noirez, L.; Kahn, R.; Keller, P.; Lambert, M.; Cohen de Lara, E.

1991-04-01

We present a first investigation of the dynamics of a side chain liquid crystal polyacrylate in the isotropic (I), nematic (N), smectic A (SA), and re-entrant nematic (NRe) phases by means of quasi-elastic neutron scattering. The motion or/and the mobility of the mesogen protons decreases as soon as the temperature decreases after the isotropic-nematic transition. The I-N and SA-NRe transitions corrspond to a jump in the curve of the Elastic Incoherent Structure Factor (ratio: elastic scattering/ total scattering) versus temperature, on the other hand the transition N-SA occurs without any change of slope. We conclude that the local order is very similar in the nematic and the smectic A phases. Nous présentons une première étude dynamique par diffusion quasi-élastique des neutrons, d'un échantillon de polyacrylate mésomorphe en peigne dans chacune des phases : isotrope, nématique, smectique et nématique rentrante. On montre que le mouvement et/ou la mobilité des protons du mésogène se restreint à mesure que la température diminue après la transition isotrope-nématique. Contrairement à la transition N-SA, les transitions I-N et SA-NRe correspondent à une discontinuité dans la courbe du Facteur de Structure Incohérent Elastique (rapport : intensité élastique/intensité totale) en fonction de la température ; l'ordre local semble donc très proche pour les phases nématique et smectique.

A fluctuating plume dispersion model for the prediction of odour-impact frequencies from continuous stationary sources

NASA Astrophysics Data System (ADS)

Mussio, P.; Gnyp, A. W.; Henshaw, P. F.

A fluctuating plume dispersion model has been developed to facilitate the prediction of odour-impact frequencies in the communities surrounding elevated point sources. The model was used to predict the frequencies of occurrence of odours of various magnitudes for 1 h periods. In addition, the model predicted the maximum odour level. The model was tested with an extensive set of data collected in the residential areas surrounding the paint shop of an automotive assembly plant. Most of the perceived odours in the vicinity of the 64, 46 m high stacks ranged between 2 and 7 odour units and generally persisted for less than 30 s. Ninety-eight different field determinations of odour impact frequencies within 1 km of the plant were conducted during the course of the study. To simplify evaluation, the frequencies of occurrence of different odour levels were summed to give the total frequency of occurrence of all readily detectable (>2 OU) odours. The model provided excellent simulation of the total frequencies of occurrence where the odour was frequent (i.e . readily detectable more than 30% of the time). At lower frequencies of occurrence the model prediction was poor. The stability class did not seem to affect the model's ability to predict field frequency values. However, the model provided excellent predictions of the maximum odour levels without being sensitive to either stability class or distance from the source. Ninety-five percent of the predicted maximum values were within a factor of two of the measured field maximum values.

Broadband VHF observations for lightning impulses from a small satellite SOHLA-1 (Maido 1)

NASA Astrophysics Data System (ADS)

Morimoto, T.; Kikuchi, H.; Ushio, T.; Kawasaki, Z.; Hidekazu, H.; Aoki, T.

2009-12-01

Lightning Research Group of Osaka University (LRG-OU) has been developing VHF Broadband Digital Interferometer (DITF) to image precise lightning channels and monitor lightning activity widely. The feature of broadband DITF is its ultrawide bandwidth (from 25MHz to 100MHz) and implicit redundancy for estimating VHF source location. LRG-OU considers an application of the broadband DITF to the spaceborne measurement system and joins the SOHLA (Space Oriented Higashi-Osaka Leading Associate) satellite project. The SOHLA satellite project represents a technology transfer program to expand the range of the space development community in Japan. The objective is to get SMEs (Small and Medium sized manufacturing Enterprises) involved in small space projects and new space technologies. Under the cooperative agreement, JAXA (Japan Aerospace Exploration Agency) intends to contribute to socio-economic development by returning its R&D results to society, and SOHLA tries to revitalize the local economy through the commercialization of versatile small satellites. According to the agreement, JAXA provides SOHLA its technical information on small satellites and other technical assistance for the development of the small satellites, SOHLA-1. The prime objective of the SOHLA-1 program is to realize low-cost and short term development of a microsatellite which utilizes the components and bus technologies of JAXA’s MicroLabSat. SOHLA-1 is a spin-stabilized microsatellite of MicroLabSat heritage (about 50 kg). The spin axis is fixed to inertial reference frame. The spin axis (z-axis) lies in the plane containing the solar direction and the normal to the orbital plane. LRG-OU takes responsibility for a science mission of SOHLA-1. To examine the feasibility of the DITF receiving VHF lightning impulses in space, LRG-OU proposes the BMW (Broadband Measurement of Waveform for VHF Lightning Impulses). BMW consists of a single pair of an antenna, a band-pass filter, an amplifier, and an analog-to-digital converter (ADC) to record broadband VHF pulses in orbit. The waveforms of 100 EM pulses in VHF band emitted from a lightning flash are obtained. Three pairs of BMW with accurate synchronized 3-channel-ADC are needed to realize DITF. From the successful satellite observation like TRMM/LIS, the effectiveness and impact of satellite observations for lightning are obvious. The combination of optical and VHF lightning observations are complimentary each other. ISS/JEM is a candidate platform to realize the simplest DITF and synchronous observations with optical sensors. SOHLA-1 was launched by a HII-A rocket at January 23, 2009 and named Maido-1. Then BMW has worked well and recorded VHF EM waveforms. The development of Maido-1 and its observations results will be presented.

Modeles numeriques de la stimulation optique de neurones assistee par nanoparticules plasmoniques

NASA Astrophysics Data System (ADS)

Le Hir, Nicolas

La stimulation de neurones par laser emerge depuis plusieurs annees comme une alternative aux techniques plus traditionnelles de stimulation artificielle. Contrairement a celles-ci, la stimulation lumineuse ne necessite pas d'interagir directement avec le tissu organique, comme c'est le cas pour une stimulation par electrodes, et ne necessite pas de manipulation genetique comme c'est le cas pour les methodes optogenetiques. Plus recemment, la stimulation lumineuse de neurones assistee par nanoparticules a emerge comme un complement a la stimulation simplement lumineuse. L'utilisation de nanoparticules complementaires permet d'augmenter la precision spatiale du procede et de diminuer la fluence necessaire pour observer le phenomene. Ceci vient des proprietes d'interaction entre les nanoparticules et le faisceau laser, comme par exemple les proprietes d'absorption des nanoparticules. Deux phenomenes princpaux sont observes. Dans certains cas, il s'agit d'une depolarisation de la membrane, ou d'un potentiel d'action. Dans d'autres experiences, un influx de calcium vers l'interieur du neurone est detecte par une augmentation de la fluorescence d'une proteine sensible a la concentration calcique. Certaines stimulations sont globales, c'est a dire qu'une perturbation se propage a l'ensemble du neurone : c'est le cas d'un potentiel d'action. D'autres sont, au contraire, locales et ne se propagent pas a l'ensemble de la cellule. Si une stimulation lumineuse globale est rendue possible par des techniques relativement bien maitrisees a l'heure actuelle, comme l'optogenetique, une stimulation uniquement locale est plus difficile a realiser. Or, il semblerait que les methodes de stimulation lumineuse assistees par nanoparticules puissent, dans certaines conditions, offrir cette possibilite. Cela serait d'une grande aide pour conduire de nouvelles etudes sur le fonctionnement des neurones, en offrant de nouvelles possibilites experimentales en complement des possibilites actuelles. Cependant, le mecanisme physique a l'origine de la stimulation lumineuse de neurones, ainsi que celui a l'orgine de la stimulation lumineuse assistee par nanoparticules, n'est a ce jour pas totalement compris. Des hypotheses ont ete formulees concernant ce mecanisme : il pourrait etre photothermique, photomecanique, ou encore photochimique. Il se pourrait egalement que plusieurs mecanismes soient a l'oeuvre conjointement, etant donne la variete des observations. La litterature ne converge pas a ce sujet et l'existence d'un mecanisme commun aux differentes situations n'a pas ete demontree.

Pratique de l’électroconvulsivothérapie dans un hôpital universitaire Tunisien

PubMed Central

Mechri, Anwar; Zaafrane, Hana; Khalifa, Monia Hadj; Toumi, Samir; Zaafrane, Férid; Gaha, Lotfi

2018-01-01

Les objectifs de cette étude étaient de décrire les modalités pratiques de l’électroconvulsivothérapie (ECT) à l’hôpital universitaire de Monastir (Tunisie). Il s'agit d'une étude rétrospective portant sur tous les patients traités par ECT à l’hôpital universitaire de Monastir entre 2002 et 2013. Le nombre des patients était de 80 patients (60 hommes et 20 femmes, d’âge moyen de 42,1±15,7 ans), représentant 1,4% de l’ensemble des patients hospitalisés en psychiatrie durant la période d’étude. Le nombre total des séances d’ECT était de 784. Le diagnostic principal était le trouble dépressif majeur isolé ou récurrent chez 50% des patients. La majorité des patients (78,8%) avait reçu une seule cure d’ECT avec un nombre moyen de séances de 8,1 ± 4,9. Le produit anesthésique le plus utilisé était le propofol (97,4%). L’énergie délivrée était comprise entre 40 et 80 joules dans 71% des cas et elle était positivement corrélée à l’âge des patients. La durée moyenne de la crise motrice était de 22,3 ± 7,2 secondes et elle était négativement corrélée à l’âge des patients. Le taux de réponse le plus élevé a été constaté au niveau des scores de dépression (64,3%). Des effets indésirables immédiats ont été mentionnés chez 51,2% des patients. Enfin, 20% des patients poursuivaient des séances d’ECT d’entretien avec un rythme uni ou bimensuel. La pratique de l’ECT à l’hôpital universitaire de Monastir reste peu développée en termes de nombre des patients et des séances d’ECT. Des efforts doivent être déployés pour promouvoir l’utilisation de cette méthode. PMID:29632628

Evaluation experimentale et theorique du comportement a la flexion de nouveaux poteaux en materiaux composites

NASA Astrophysics Data System (ADS)

Metiche, Slimane

La demande croissante en poteaux pour les differents reseaux d'electricite et de telecommunications a rendu necessaire l'utilisation de materiaux innovants, qui preservent l'environnement. La majorite des poteaux electriques existants au Canada ainsi qu'a travers le monde, sont fabriques a partir de materiaux traditionnels tel que le bois, le beton ou l'acier. Les motivations des industriels et des chercheurs a penser a d'autres solutions sont diverses, citons entre autre: La limitation en longueur des poteaux en bois ainsi que la vulnerabilite des poteaux fabriques en beton ou en acier aux agressions climatiques. Les nouveaux poteaux en materiaux composites se presentent comme de bons candidats a cet effet, cependant; leur comportement structural n'est pas connu et des etudes theoriques et experimentales approfondies sont necessaires avant leur mise en marche a grande echelle. Un programme de recherche intensif comportant plusieurs projets experimentaux, analytiques et numeriques est en cours a l'Universite de Sherbrooke afin d'evaluer le comportement a court et a long termes de ces nouveaux poteaux en Polymeres Renforces de Fibres (PRF). C'est dans ce contexte que s'inscrit la presente these, et notre recherche vise a evaluer le comportement a la flexion de nouveaux poteaux tubulaires coniques fabriques en materiaux composites par enroulement filamentaire et ce, a travers une etude theorique, ainsi qu'a travers une serie d'essais de flexion en "grandeur reelle" afin de comprendre le comportement structural de ces poteaux, d'optimiser la conception et de proposer une procedure de dimensionnement pour les utilisateurs. Les poteaux en Polymeres Renforces de Fibres (PRF) etudies dans cette these sont fabriques avec une resine epoxyde renforcee de fibres de verre type E. Chaque type poteaux est constitue principalement de trois zones ou les proprietes geometriques (epaisseur, diametre) et les proprietes mecaniques sont differentes d'une zone a l'autre. La difference entre ces proprietes est due au nombre de couches utilisees dans chaque zone ainsi qu'a l'orientation des fibres de chaque couche. Un total de vingt-trois prototypes de dimensions differentes; ont ete testes en flexion jusqu'a la rupture. Deux types de fibres de verre de masses lineaires differentes, ont ete utilisees afin d'evaluer l'effet du type de fibres sur le comportement a la flexion. Un nouveau montage experimental permettant de tester tous les types de poteaux en PRF a ete dimensionne et fabrique selon les recommandations decrites dans les normes ASTM D 4923-01 et ANSI C 136.20-2005. Un modele analytique base sur la theorie des poutres en elasticite lineaire est propose dans cette these. Ce modele predit avec une bonne precision le comportement experimental charge---deflexion ainsi que la deflexion maximale au sommet des poteaux en PRF; constitues de plusieurs zones de caracteristiques geometriques et mecaniques differentes. Une procedure de dimensionnement des poteaux en PRF, basee sur les resultats experimentaux obtenus dans le cadre de la presente these, est egalement proposee. Les resultats obtenus dans le cadre de la presente these permettront le developpement et l'amelioration des regles de conception utiles et pratiques a l'usage des concepteurs et des industriels du domaine des poteaux en PRF. Les retombees de cette recherche sont a la fois economiques et technologiques, car les resultats obtenus constitueront une banque de donnees qui contribueront au developpement des normes de calcul, et par consequent a l'optimisation des materiaux utilises, et serviront a valider de futurs resultats et modeles theoriques.

A Hands-On, Interdisciplinary Laboratory Program and Educational Model to Strengthen a Radar Curriculum for Broad Distribution

ERIC Educational Resources Information Center

Yeary, Mark; Yu, Tian-You; Palmer, Robert; Biggerstaff, Michael; Fink, L. Dee; Ahem, Carolyn; Tarp, Keli Pirtle

2007-01-01

This paper describes the details of a National Science Foundation multi-year educational project at the University of Oklahoma (OU). The goal of this comprehensive active-learning and hands-on laboratory program is to develop an interdisciplinary program, in which engineering, geoscience, and meteorology students participate, which forms a…

Industri-Plex, OU-1, Master Cover Certification Report: Industri-Plex Site: September 30, 2008: Appendix C, C.1-C.2

EPA Pesticide Factsheets

2012-04-22

... Sincerely, \\ -/) I iJ/;5.~~.k. -r--7~.~~- ... 2.i:

Production and Consumption of University Linked Data

ERIC Educational Resources Information Center

Zablith, Fouad; Fernandez, Miriam; Rowe, Matthew

2015-01-01

Linked Data increases the value of an organisation's data over the web by introducing explicit and machine processable links at the data level. We have adopted this new stream of data representation to produce and expose existing data within The Open University (OU) as Linked Data. We present in this paper our approach for producing the data,…

Digital Badging at The Open University: Recognition for Informal Learning

ERIC Educational Resources Information Center

Law, Patrina

2015-01-01

Awarding badges to recognise achievement is not a new development. Digital badging now offers new ways to recognise learning and motivate learners, providing evidence of skills and achievements in a variety of formal and informal settings. Badged open courses (BOCs) were piloted in various forms by the Open University (OU) in 2013 to provide a…

Individual, social and environmental determinants of sleep among women: Protocol for a systematic review and meta-analysis

USDA-ARS?s Scientific Manuscript database

Sleep is important to promote optimal health and avoid negative health outcomes. Short-duration and low-quality sleep may be more common and more detrimental among women compared with men. Identifying the determinants of behaviour is one of the first steps in designing effective interventions. To ou...

Identifying quantitative trait loci (QTLs) and developing diagnostic markers linked to orange rust resistance in sugarcane (Saccharum spp.)

USDA-ARS?s Scientific Manuscript database

Sugarcane (Saccharum spp.) is an important economic crop, contributing up to 80% of table sugar used in the world and has become a promising feedstock for biofuel production. Sugarcane production has been threatened by many diseases, and fungicide applications for disease control have been opted ou...

U.S. EPA, Pesticide Product Label, TRI-CON 50/50, 09/07/1988

EPA Pesticide Factsheets

2011-04-19

... c ••• • .r. Store c,U,,".r. uprl,ht ••• cu .... to • r.",10 .. r ... ll to p ..... It .. t tI,pl"9. COlnd.r •• h .. ,,1<1 .. ot b •• ubj.cUd to .. ou,hh .... lln' or •• ch.nlcd .bocll ... ...

Le futur linguistique: temps lineaire ou temps ramifie (The Linguistic Future: Linear or Branching Time)?

ERIC Educational Resources Information Center

Martin, Robert

1981-01-01

Discusses the problems posed by a semantic analysis of the future tense in French, addressing particularly its double use as a tense and as a mood. The distinction between linear and branching time, or, certainty and possibility, central to this discussion, leads to a comparative analysis of future and conditional. (MES)

National Register Testing of 42 Prehistoric Archeological Sites on Fort Hood, Texas: The 1996 Season

DTIC Science & Technology

1999-12-01

alluvium ca. 1100- 1000 B.P. The fact that flood stabilization, pedo - genesis, and accompanying increases in C4 395 National Register Testing at Fort...JVC TK-107OU Color Video Camera mounted on a Zeiss petrographic microscope using a 10X objective lens. The images were saved and imported into Adobe

Semiconductor Deposition and Etching Interactions of Laser-Generated Translationally Hot Atoms and Radicals

DTIC Science & Technology

1991-05-01

fluorescence," J. Chem. Phys. 86, 6731 (1987). J. E. Smedley , H. K. Haugen and S. R. Leone, "Collision-induced dissociation of laser- excited Br 2 [B3Fl(Ou... Robert J. Levis, postdoc, presently Assistant Professor of Chemistry, Wayne State University. Lisa M. Cousins, graduate student, Ph.D. 1989, presently

Final Panel Report on Allergenics

Center for Biologics Evaluation and Research (CBER)

... It il;l J:l'1t! op:i.qion .o;th~ Panel t.ha,t t;h~r~. is non~w ra:v:l,cl~;nC7~i!, to sug~~t;:I,t ,that proc~~~gq ~u+l?at;r~~e :$,ou;r~~ Qt.sp,e~ira!3~P,~};f:f,Jc ...

Predicting spillover risk to non-target plants pre-release: Bikasha collaris a potential biological control agent of Chinese tallowtree (Triadica sebifera)

USDA-ARS?s Scientific Manuscript database

Quarantine host range tests accurately predict direct risk of biological control agents to non-target species. However, a well-known indirect effect of biological control of weeds releases is spillover damage to non-target species. Spillover damage may occur when the population of agents achieves ou...

Open Science: Trends in the Development of Science Learning

ERIC Educational Resources Information Center

Scanlon, Eileen

2011-01-01

This article comments on some trends in the evolution of science teaching at a distance using the Open University UK (OU UK) experience as a benchmark. Even from the first years of the university there was an understanding of the potential role for media in developing methods for teaching science at a distance, in particular the potential for…

Proceedings of the Conference of the International Group for the Psychology of Mathematics Education (PME) (15th, Assisi, Italy, June 29-July 4, 1991), Volume 3.

ERIC Educational Resources Information Center

Furinghetti, Fulvia, Ed.

Research reports from the annual conference of the International Group for the Psychology of Mathematics Education include: "La construcion algorithmique: niveaux ou stades?" (Mesquita); "For Establishing the Generality of Conjectures" (Miyazaki); "Teachers' Attitudes Towards Mathematics and Mathematics Teaching:…

75 FR 18550 - Notice of Lodging of Consent Decree Under the Comprehensive Environmental Response, Compensation...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-12

..., and calls for covering contaminated soil at OU3 with a cap that complies with Ohio solid waste... soil and soil vapor; and a combination of dredging, off- site disposal and/or capping of contaminated.... Comments should be addressed to the Assistant Attorney General, Environment and Natural [[Page 18551...

MHD Flow Control

DTIC Science & Technology

2006-09-01

Umj) flj + GjE(Umj)flyjI A S + fS do (3.7)I This system (3.6) is integrated in time using explicit low-memory Runge-Kutta method: I U o=U" Ui =UO - ci At...signals are registered by the four-channel digital memory oscilloscopes Tektronix TDS 2414 and ASK 3107. Scheme of operation The scheme of the experiment is

Ten Years of Open Practice: A Reflection on the Impact of OpenLearn

ERIC Educational Resources Information Center

Law, Patrina; Jelfs, Anne

2016-01-01

The Open University (OU) makes a proportion of all its taught modules available to the public via OpenLearn each year. This process involves the modification, of module excerpts, showcasing subject matter and teaching approach. This activity serves both the University's social and business missions through the delivery of free courses to the…

Superfund record of decision (EPA Region 4): Aberdeen Pesticide Dumps Site, Aberdeen, NC, October 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-07-01

The decision document presents the selected remedial action for Operable Unit Three (OU3) of the Aberdeen Pesticide Dumps Site (the 'Site'), in Aberdeen, North Carolina. The remedy selected addresses groundwater, sediment, and surface water contamination and ecological concerns to eliminate or reduce the risks posed by the Site.

Environnement et approche fonctionnelle ou les processus d'un systeme ouvert (The Environment and a Functional Approach or the Processes of an Open System).

ERIC Educational Resources Information Center

Catalan, Robert

1982-01-01

Discusses the relationship between the person learning a foreign language, the methodology employed, and the environment using the paradigms of T. Parsons. Notes that the functional method has adapted some of these functions and suggests ways to incorporate the others. (AMH)

La terminologie, outil et/ou objet pedagogique (Terminology, Instructional Tool and/or Object).

ERIC Educational Resources Information Center

Van Deth, Jean-Pierre

1990-01-01

It is proposed that while interest has focused on specialized professional vocabulary as an object of language instruction, the same vocabulary can be viewed as a tool for teaching. The exchange of concepts and terminology between student and teacher improves student understanding of the language and the problems of translation. (MSE)

Stratégie de prise en charge de l'hypertension artérielle en hémodialyse chronique: un modèle appliqué d’éducation thérapeutique des patients (ETP)

PubMed Central

El Harraqui, Ryme; Naima, Abda; Yassamine, Bentata; Haddiya, Intissar

2014-01-01

Même après l'entrée en dialyse, la prévalence de l'hypertension artérielle (HTA) reste élevée. Elle est souvent greffée d'une forte morbi-mortalité, et altère la qualité de vie des patients hémodialysés chroniques. La « méthode du poids sec (PS) », établie par Scribner, présente un intérêt indéniable dans la gestion de l'HTA chez le patient hémodialysé. Le but de notre travail était de déterminer la prévalence et les facteurs de risque (FDR) de l'HTA chez nos hémodialysés chroniques et d'en tenter une réduction en nous basant sur une stratégie d’éducation thérapeutique basée sur les recommandations de Scribner. Nous avons mené une étude prospective interventionnelle en trois mois et en trois phases, auprès des 93 hémodialysés chroniques de l'Hôpital Al Farabi d'Oujda. En phase 1, nous avons déterminé la prévalence de l'HTA par la surveillance horaire de la tension artérielle (TA) durant la séance de dialyse pendant deux semaines, soit sur un total de 442 séances. Les patients ont également mesuré leur pression artérielle (PA) hors-centre de façon biquotidienne les jours de non-dialyse, soit un total de 1720 mesures hors-centre. L'HTA a été définie par une Pression Artérielle Systolique (PAS) supérieure ou égale à 140mmHg et/ou une Pression Artérielle Diastolique (PAD) supérieure ou égale à 90mmHg sur au moins 2 mesures. En phase 2, les patients hypertendus ont bénéficié d'une prise en charge basée sur les recommandations de Scribner et une éducation thérapeutique (ETP). En phase 3, nous évalué les retombées de notre prise en charge. Une HTA a été notée sur 231 séances chez 57 patients, soit une prévalence de 61,3%. La PAS moyenne était de 172,75±17,69 (145-220) mmHg. Les FDR retenus sont: l’âge, la PPID importante, le non respect des règles hygiéno-diététiques (RHD) et le rythme de 2 séances de dialyse/semaine. Au départ, 13 patients (22,8%) étaient dialysés trois fois par semaine; nous avons doublé ce taux. Nous avons également réduit le PS chez 48 patients, à raison de ½Kg tous les 15 jours. Les résultats en phase 3 montrent que 8 patients sont passés dans le groupe des patients «normotendus », la prévalence de l'HTA passant ainsi à 52,7%. Dans le nouveau groupe «HTA + » (n = 49), la PAS moyenne est passée à 166,12±17,05 (140-200) mmHg. La PPID a baissé de 0,98±0,425 (0,35-2,1) Kgs chez 46 patients. La prévalence de l'HTA dans notre population rejoint les données de la littérature, mais en appliquant les principes de l'ETP à la prise en charge de celle-ci, nous avons pu en baisser la prévalence. Ainsi, La « méthode du PS » peut permettre de corriger l'HTA en HD, mais ce succès ne doit se concevoir sans un effort pédagogique soutenu de la part de l'ensemble de l’équipe soignante, d'où l'intérêt de planifier une ETP PMID:25722759

Influence of heart failure on resting lung volumes in patients with COPD.

PubMed

Souza, Aline Soares de; Sperandio, Priscila Abreu; Mazzuco, Adriana; Alencar, Maria Clara; Arbex, Flávio Ferlin; Oliveira, Mayron Faria de; O'Donnell, Denis Eunan; Neder, José Alberto

2016-01-01

To evaluate the influence of chronic heart failure (CHF) on resting lung volumes in patients with COPD, i.e., inspiratory fraction-inspiratory capacity (IC)/TLC-and relative inspiratory reserve-[1 - (end-inspiratory lung volume/TLC)]. This was a prospective study involving 56 patients with COPD-24 (23 males/1 female) with COPD+CHF and 32 (28 males/4 females) with COPD only-who, after careful clinical stabilization, underwent spirometry (with forced and slow maneuvers) and whole-body plethysmography. Although FEV1, as well as the FEV1/FVC and FEV1/slow vital capacity ratios, were higher in the COPD+CHF group than in the COPD group, all major "static" volumes-RV, functional residual capacity (FRC), and TLC-were lower in the former group (p < 0.05). There was a greater reduction in FRC than in RV, resulting in the expiratory reserve volume being lower in the COPD+CHF group than in the COPD group. There were relatively proportional reductions in FRC and TLC in the two groups; therefore, IC was also comparable. Consequently, the inspiratory fraction was higher in the COPD+CHF group than in the COPD group (0.42 ± 0.10 vs. 0.36 ± 0.10; p < 0.05). Although the tidal volume/IC ratio was higher in the COPD+CHF group, the relative inspiratory reserve was remarkably similar between the two groups (0.35 ± 0.09 vs. 0.44 ± 0.14; p < 0.05). Despite the restrictive effects of CHF, patients with COPD+CHF have relatively higher inspiratory limits (a greater inspiratory fraction). However, those patients use only a part of those limits, probably in order to avoid critical reductions in inspiratory reserve and increases in elastic recoil. Avaliar a influência da insuficiência cardíaca crônica (ICC) nos volumes pulmonares de repouso em pacientes com DPOC, ou seja, fração inspiratória -capacidade inspiratória (CI)/CPT - e reserva inspiratória relativa - [1 - (volume pulmonar inspiratório final/CPT)]. Após cuidadosa estabilização clínica, 56 pacientes com DPOC (24 alocados no grupo DPOC+ICC; 23 homens/1 mulher) e 32 (28 homens/4 mulheres) com DPOC isolada foram submetidos à espirometria forçada e lenta e pletismografia de corpo inteiro. Os pacientes do grupo DPOC+ICC apresentaram maior VEF1, VEF1/CVF e VEF1/capacidade vital lenta; porém, todos os principais volumes "estáticos" - VR, capacidade residual funcional (CRF) e CPT - foram menores que aqueles do grupo DPOC (p < 0,05). A CRF diminuiu mais do que o VR, determinando assim menor volume de reserva expiratória no grupo DPOC+ICC que no grupo DPOC. Houve redução relativamente proporcional da CRF e da CPT nos dois grupos; logo, a CI também foi similar. Consequentemente, a fração inspiratória no grupo DPOC+ICC foi maior que no grupo DPOC (0,42 ± 0,10 vs. 0,36 ± 0,10; p < 0,05). Embora a razão volume corrente/CI fosse maior no grupo DPOC+ICC, a reserva inspiratória relativa foi notadamente similar entre os grupos (0,35 ± 0,09 vs. 0,44 ± 0,14; p < 0,05). Apesar dos efeitos restritivos da ICC, pacientes com DPOC+ICC apresentam elevações relativas dos limites inspiratórios (maior fração inspiratória). Entretanto, esses pacientes utilizam apenas parte desses limites, com o provável intuito de evitar reduções críticas da reserva inspiratória e maior trabalho elástico.

Sources and sinks of filtered total mercury and concentrations of total mercury of solids and of filtered methylmercury, Sinclair Inlet, Kitsap County, Washington, 2007-10

USGS Publications Warehouse

Paulson, Anthony J.; Dinicola, Richard S.; Noble, Marlene A.; Wagner, Richard J.; Huffman, Raegan L.; Moran, Patrick W.; DeWild, John F.

2012-01-01

The majority of filtered total mercury in the marine water of Sinclair Inlet originates from salt water flowing from Puget Sound. About 420 grams of filtered total mercury are added to Sinclair Inlet each year from atmospheric, terrestrial, and sedimentary sources, which has increased filtered total mercury concentrations in Sinclair Inlet (0.33 nanograms per liter) to concentrations greater than those of the Puget Sound (0.2 nanograms per liter). The category with the largest loading of filtered total mercury to Sinclair Inlet included diffusion of porewaters from marine sediment to the water column of Sinclair Inlet and discharge through the largest stormwater drain on the Bremerton naval complex, Bremerton, Washington. However, few data are available to estimate porewater and stormwater releases with any certainty. The release from the stormwater drain does not originate from overland flow of stormwater. Rather total mercury on soils is extracted by the chloride ions in seawater as the stormwater is drained and adjacent soils are flushed with seawater by tidal pumping. Filtered total mercury released by an unknown freshwater mechanism also was observed in the stormwater flowing through this drain. Direct atmospheric deposition on the Sinclair Inlet, freshwater discharge from creek and stormwater basins draining into Sinclair Inlet, and saline discharges from the dry dock sumps of the naval complex are included in the next largest loading category of sources of filtered total mercury. Individual discharges from a municipal wastewater treatment plant and from the industrial steam plant of the naval complex constituted the loading category with the third largest loadings. Stormwater discharge from the shipyard portion of the naval complex and groundwater discharge from the base are included in the loading category with the smallest loading of filtered total mercury. Presently, the origins of the solids depositing to the sediment of Sinclair Inlet are uncertain, and consequently, concentrations of sediments can be qualitatively compared only to total mercury concentrations of solids suspended in the water column. Concentrations of total mercury of suspended solids from creeks, stormwater, and even wastewater effluent discharging into greater Sinclair Inlet were comparable to concentrations of solids suspended in the water column of Sinclair Inlet. Concentrations of total mercury of suspended solids were significantly lower than those of marine bed sediment of Sinclair Inlet; these suspended solids have been shown to settle in Sinclair Inlet. The settling of suspended solids in the greater Sinclair Inlet and in Operable Unit B Marine of the naval complex likely will result in lower concentrations of total mercury in sediments. Such a decrease in total mercury concentrations was observed in the sediment of Operable Unit B Marine in 2010. However, total mercury concentrations of solids discharged from several sources from the Bremerton naval complex were higher than concentrations in sediment collected from Operable Unit B Marine. The combined loading of solids from these sources is small compared to the amount of solids depositing in OU B Marine. However, total mercury concentration in sediment collected at a monitoring station just offshore one of these sources, the largest stormwater drain on the Bremerton naval complex, increased considerably in 2010. Low methylmercury concentrations were detected in groundwater, stormwater, and effluents discharged from the Bremerton naval complex. The highest methylmercury concentrations were measured in the porewaters of highly reducing marine sediment in greater Sinclair Inlet. The marine sediment collected off the largest stormwater drain contained low concentrations of methylmercury in porewater because these sediments were not highly reducing.

Bilateral uveitis and hyphema in a Catalina Macaw (Ara ararauna x Ara macao) associated with multicentric lymphoma

USDA-ARS?s Scientific Manuscript database

A 20-year-old, female Catalina macaw (Ara ararauna × Ara macao) was presented with bilateral uveitis and hyphema. The hyphema initially improved with 0.12% prednisolone acetate ophthalmic drops (1 drop OU q4h for 7 days), but the hyphema recurred after the drops were tapered. The bird subsequently d...

Nuclear Forensic Field Exercise #1

DTIC Science & Technology

2006-11-01

Ottawa; novembre 2006. Introduction ou contexte Un exercice radiologique pratique a été organisé à l’appui du projet 04-0030TD de l’IRTC. Les...11 List of symbols/abbreviations/acronyms/initialisms ..................................................................... 13 viii DRDC...R&D Canada - Ottawa. 12 DRDC Ottawa TM 2006-214 This page intentionally left blank. DRDC Ottawa TM 2006-214 13 List of symbols/abbreviations

Actes des Journees de linguistique (Proceedings of the Linguistics Conference) (14th, Quebec, Canada, March 23-24, 2000).

ERIC Educational Resources Information Center

Perron, Veronique, Ed.

Papers on language research in this volume include the following: Phonetique ou phonologie: le chva dans les emprunts anglais en portugais (Phonetics or Phonology: The Schwa in English Loan Words to Portuguese) (Pascale Belanger); NewsExpert: exemple de l'application de la linguistique informatique a Internet (NewsExpert: An Example of Its…

Shift in the National Drug Strategy: Implications for the SOUTHCOM AOR

DTIC Science & Technology

1994-06-17

NT.F:C.,ThON ! .’.NUI SER -4. 70,... l lOU R, -, Cf CE OF IL l NI l .. ELEV•ENT NO. . NO ACCESS’ON NO. 11. TITLE (. ict .*e Security Cla.ficaeionj SHIFT IN...illegal drugs and cooperate in international efforts.22 In Colombia, the Gaviria government challenged the violence of the Medellin Cartel capturing key

Pilot Study to Aid in the Designing of Research on the Officer Candidate Training Program. PJ-3407-01

DTIC Science & Technology

1952-08-01

Coadidate Scbhol, Aberden Proving Oromds, Md. 20 G The Antiaircraft sa OuGided Misiles Brach Officer Canidate School, Fort B11.., Temaw 22 9 The Army...M4onmouth, N. J. R The Infantry Officer Candidate School, Fort BenninG, Georgia F The Ordnance Officer Candidate School, Aberdeen Proving Grounds , Md

Beyond Competencies: What Higher Education Assessment Could Offer the Workplace and the Practitioner-Researcher

ERIC Educational Resources Information Center

Harvey, Morag; Norman, Lyn

2007-01-01

This article is based on research and development carried out at the Centre for Outcomes-Based Education at the Open University (OU). It explores the way in which higher education (HE) assessment could meet specific criteria in order to assess the unique qualities that underpin the relationship between practitioner-researchers and the workplace.…

Letter from Galo Jackson, USEPA to Prashant Gupta, Honeywell International, Inc. Subject: Leaching to Groundwater OU3 (Uplands) Baseline Human Health Risk Assessment

EPA Pesticide Factsheets

May 27, 2011 letter in response to a request for a status letter for the LCP Chemicals Superfund site and interest in selling Parcel B05308053001 and Tract 4 of Parcel B007800000001 in Brunswick, Georgia. Region ID: 04 DocID: 10748549, DocDate: 05-27-2011

Recognising Informal Elearning with Digital Badging: Evidence for a Sustainable Business Model

ERIC Educational Resources Information Center

Law, Patrina

2015-01-01

Digital badging as a trend in education is now recognised. It offers a way to reward and motivate, providing evidence of skills and achievements. Badged Open Courses (BOCs) were piloted by The Open University (OU) in 2013. The project built on research into the motivations and profiles of learners using free educational resources which the OU…

Collaborative evaluation of the healthy habits program: an effective community intervention to improve mobility and cognition of Chinese older adults living in the U.S

USDA-ARS?s Scientific Manuscript database

Objectives: There is a growing demand to reduce ethnic health disparities. The Healthy Habits Program (HHP) was implemented to provide a community-based physical activity and education intervention for Chinese older adults living in Boston, Massachusetts. This study evaluated the HHP by assessing ou...

The MAGIC of Web Tutorials: How One Library (Re)Focused Its Delivery of Online Learning Objects on Users

ERIC Educational Resources Information Center

Hess, Amanda Nichols

2013-01-01

Oakland University (OU) Libraries undertook an assessment of how to leverage its resources to make online tutorials more focused on users' needs. A multi-part assessment process reconsidered Web tutorials offerings through the lenses of faculty and staff feedback, literature review, and an analysis of other universities' online tutorial offerings.…

77 FR 74222 - Notice of Lodging of Consent Decree Under the Comprehensive Environmental Response, Compensation...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-13

... protection of public health and the environment. The cleanup goal for surface soil is PCBs of 25 ppm which is... and Highway 202. The selected remedy for OU-3 is soil capping and expanded groundwater extraction. The objectives of the remedial action for soils include: Reducing risks to area workers and trespassers from...

Relocation of Joint Munitions Storage Area. Environmental Assessment

DTIC Science & Technology

2008-10-01

N IT IO N S S TO R A G E A R EA D S ou rc e: A nd re w +s A FB Fi gu re 3 -1 . N oi se C on to ur s at A nd re w s...Liriodendron tulipifera). Mountain laurel (Kalmia latifolia), highbush blueberry (Vaccinium corymbosum), and Christmas fern (Polystichium acrostichoides

Nutritional Relationships in Schistosomiasis.

DTIC Science & Technology

1978-07-01

to presence of ou~bain, phlorizin, phloretin . 1lexose mediated accumulation is Na coupled. Accession For NTIS GREA&I DDC TAB Unannounced...mediat,!d system is apparently Na + dependent and sensitive to presence of ouabain, phlorizin, phloretin . Hexose mediated accumulation is Na+ coupled. i...decreased Na+, ouabain, phiorizin phloretin and other sugars. Studies with Na22 suggest that the accumulation of 2-deoxyglucose and Na+ were coupled

The use of home-based therapy with ready-to-use therapeutic food to treat malnutrition in a rural area during a food crisis

USDA-ARS?s Scientific Manuscript database

When the international community declared a famine in Malawi in January 2006, emergency food aid reached only populations with pre-existing health care services. To treat the widespread childhood malnutrition in Machinga district, a rural area lacking health care facilities, in February 2006 five ou...

Hypersonic Flight: Time To Go Operational

DTIC Science & Technology

2013-02-14

and turbojet /turbofan driven aircraft both individually and combined with the latter taking over fighter propulsion in 1945-1948 and quickly...2000 2020 Early Turbojet / Turbofan Piston Aircraft Late Turbojet / Turbofan Year Deployed M ile s pe r H ou 6 ensure the...threaten aircraft , airbases, and naval assets, especially aircraft carrier battle groups. The future is uncertain and the preceding vision of the

"Le Petit Prince" ou la bonne pedagogie: Une analyse semiotique des structures didactiques ("The Little Prince" or Good Teaching: A Semiotic Analysis of Didactic Structures).

ERIC Educational Resources Information Center

Kaminskas, Jurate

1983-01-01

Saint-Exupery's story, "The Little Prince," is analyzed from the point of view of the structures through which the author wishes to inspire and instruct the reader. The use of disguised didactic discourse and the manipulation of words toward this end are examined. (MSE)

Letter from Galo Jackson, USEPA to Prashant Gupta, Honeywell, Inc. Subject: Human Health Risk Assessment for the Estuary, OU1: LCP Chemicals Superfund Site, Brunswick, Glynn County, Georgia

EPA Pesticide Factsheets

contains Nov. 30, 2011 letter from EPA Region 4 to notify Honeywell that EPA is approving its draft assessment and directing Honeywell to submit the draft remedial investigation report. Region ID: 04 DocID: 10841434, DocDate: 11-30-2011

Lightcurves and Periods for Asteroids 1081 Reseda 2117 Danmark, 2315 Czechoslovakia, 2871 Schober, 6392 Takashimizuno, and (6409) 1992 VC

NASA Astrophysics Data System (ADS)

Yankov, Arten; Ditteon, Richard

2009-01-01

Ten asteroids were observed at the Oakley Southern Sky Observatory on six nights during the months of 2008 July and August. The asteroids were 1081 Reseda, 1421 Esperanto, 2117 Danmark, 2315 Czechoslovakia, 2871 Schober, 6392 Takashimizuno, (6409) 1992 VC, 7046 Reshetnev, (14276) 2000 CF2, and (32219) 2000 OU20.

Quels outils pour l'analyse linguistique ou les prealables d'un enseignement de la grammaire? (What Tools for Linguistic Analysis or Preliminaries for Grammar Instruction?)

ERIC Educational Resources Information Center

Darot, Mireille

1983-01-01

The usefulness of classifications within and comparisons among languages as a means of discovering the commonalities of human language is discussed. Metalinguistics offers not only the potential for analyzing the specifics of each language, but also the tools for teaching across languages. (MSE)

Le Jeu de la regle et du hasard, ou comment rehabiliter la grammaire en jouant avec la litterature (The Game by the Rules or by Chance, Or How to Rehabilitate Grammar while Playing with Literature)

ERIC Educational Resources Information Center

Gaudin, Colette; Kogan, Vivian

1975-01-01

This article proposes the use of literary texts as a means of teaching French grammar, and to help remedy problems encountered in learning, particularly by intermediate-level students. (Text is in French.) (CLK)

Effects of catastrophic events on transportation system management and operations : executive summary of the August 2003 northeast blackout, Great Lakes and New York City regions

DOT National Transportation Integrated Search

2004-05-01

On Thursday, August 14, 2003, a series of seemingly small events, happening in concert, produced the largest blackout in American history. Shortly after 2:00 p.m. on August 14, a brush fire caused a transmission line south of Columbus, Ohio, to go ou...

Brevipalpus phoenicis (Geijskes) sensu lato (Acari:Tenuipalpidae) no Brasil

USDA-ARS?s Scientific Manuscript database

Os ácaros tenuipalpídeos ou ácaros planos são importantes fitófagos constituintes do agroecossistema e florestas semitropical e tropical (JEPPSON et al., 1975; HOY, 2011), sendo que algumas espécies estão associadas à transmissão de fitovírus (CHAGAS et al., 2001 e 2003; CHILDERS et al., 2001; KITAJ...

Phytoremediation of Hazardous Wastes

DTIC Science & Technology

1995-07-26

TITLE AND SUBTITLE Phytoremediation of Hazardous Wastes 6. AUTHOR(S) Steven C. McCutcheon, N. Lee Wolfe, Laura H. Carreria and Tse-Yuan Ou 5... phytoremediation (the use of plants to degrade hazardous contaminants) was developed. The new approach to phytoremediation involves rigorous pathway analyses...SUBJECT TERMS phytoremediation , nitroreductase, laccase enzymes, SERDP 15. NUMBER OF PAGES 8 16. PRICE CODE N/A 17. SECURITY CLASSIFICATION OF

Contribution to the study of the zonal variation of the climate aridity in central northern Sahara (Algeria)

NASA Astrophysics Data System (ADS)

Benseghier-Hadjaidji, Fatiha; Talbi, Nadjib; Derridj, Arezki

2018-05-01

The environment degradation at the level of all its compartments which we notice at present, calls us to the risks that it would underestimate the climatic and consequently bioclimatic crisis there, in the North as in the South of the Mediterranean region. To protect the environment is not a luxury. In this respect, we wondered about the zonal variation of the climate aridity at the level of three bordering climatic stations: El-Oued, Touggourt and Ouargla. These are distant from 160 km on average some of the others. For that purpose, we based ourselves on the statistical tool the software "instat +" for the estimation of the ETP (PM) and afterward the determination of the pluvio-evapotranspiration "quotient P/ETP". For this analysis, the climatic data spread out over a period of 20 years. The results allowed to specify the aridity degree of the studied zone. So, they reveal a mitigation of the aridity of the climate in Touggourt and El-Oued while the hyper-aridity distinguishes well the Ouargla region. This approach contributes to a better knowledge of the dry ecosystems. This is important to indicate it to turn better in the eremologic search later.

Análise da aplicação e dos resultados do modelo OPM3® para a área da saúde

PubMed Central

Augusto dos Santos, Luis; de Fátima Marin, Heimar

2015-01-01

Esta pesquisa procurou analisar se um modelo de questionário criado por uma comunidade internacional de gerenciamento de projetos e se é aplicavél a organizações voltadas a área de saúde. O modelo OPM3® (Organizational Project Management Maturity Model) foi criado para que organizações de qualquer área ou porte pudessem identificar a presença, ou ausência, de boas práticas de gerenciamento. O objetivo da aplicação desse modelo é avaliar sempre a organização e não o entrevistado. No presente artigo, são apresentados os resultados da aplicação desse modelo em uma organização que possuía produtos e serviços de tecnologia da informação aplicados à área de saúde. Este estudo verificou que o modelo é aplicável de forma rápida e que a organização analisada possuía um número expressivo de boas práticas. PMID:26924862

Interatomic interaction effects on second-order momentum correlations and Hong-Ou-Mandel interference of double-well-trapped ultracold fermionic atoms

NASA Astrophysics Data System (ADS)

Brandt, Benedikt B.; Yannouleas, Constantine; Landman, Uzi

2018-05-01

Identification and understanding of the evolution of interference patterns in two-particle momentum correlations as a function of the strength of interatomic interactions are important in explorations of the nature of quantum states of trapped particles. Together with the analysis of two-particle spatial correlations, they offer the prospect of uncovering fundamental symmetries and structure of correlated many-body states, as well as opening vistas into potential control and utilization of correlated quantum states as quantum-information resources. With the use of the second-order density matrix constructed via exact diagonalization of the microscopic Hamiltonian, and an analytic Hubbard-type model, we explore here the systematic evolution of characteristic interference patterns in the two-body momentum and spatial correlation maps of two entangled ultracold fermionic atoms in a double well, for the entire attractive- and repulsive-interaction range. We uncover quantum-statistics-governed bunching and antibunching, as well as interaction-dependent interference patterns, in the ground and excited states, and interpret our results in light of the Hong-Ou-Mandel interference physics, widely exploited in photon indistinguishability testing and quantum-information science.

Water resources between conditions of quality and quantity in the Oued Souf region!

NASA Astrophysics Data System (ADS)

Miloudi, Abdelmonem; Remini, Bouallem

2018-05-01

Waters from the Terminal complex (TC) in the Souf region have been gushing since Spring1956 through the first drilling carried out in the municipality of Guemmar (El-Oued) to ensure the need for drinking water requirements. Water needs of the habitat and farmers are increasing with the population growth in the Souf region; there are 153 boreholes in the Terminal complex for Habitat needs, of which more than 80% are available for drinking water supply. These needs are causing negative consequences for the serene life of the Souafa by the phenomenon of water upwellings, the free water table, and the change in the quality of the waters from the Terminal complex. Our work will be conducted to produce a piezometric map of the Souf Terminal complex and to conduct a study on the quality of water resources in the Algerian south-east, leading to a diagnosis of pollution and its impact on the water. The quality of water resources is examined by the establishment of sampling and water analysis campaigns for both irrigation and public consumption, following the static measurement of water levels in the network boreholes of TC Monitoring.

Decoherence and tripartite entanglement dynamics in the presence of Gaussian and non-Gaussian classical noise

NASA Astrophysics Data System (ADS)

Kenfack, Lionel Tenemeza; Tchoffo, Martin; Fai, Lukong Cornelius; Fouokeng, Georges Collince

2017-04-01

We address the entanglement dynamics of a three-qubit system interacting with a classical fluctuating environment described either by a Gaussian or non-Gaussian noise in three different configurations namely: common, independent and mixed environments. Specifically, we focus on the Ornstein-Uhlenbeck (OU) noise and the random telegraph noise (RTN). The qubits are prepared in a state composed of a Greenberger-Horne-Zeilinger (GHZ) and a W state. With the help of the tripartite negativity, we show that the entanglement evolution is not only affected by the type of system-environment coupling but also by the kind and the memory properties of the considered noise. We also compared the dynamics induced by the two kinds of noise and we find that even if both noises have a Lorentzian spectrum, the effects of the OU noise cannot be in a simple way deduced from those of the RTN and vice-versa. In addition, we show that the entanglement can be indefinitely preserved when the qubits are coupled to the environmental noise in a common environment (CE). Finally, the presence or absence of peculiar phenomena such as entanglement revivals (ER) and entanglement sudden death (ESD) is observed.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Strickland, Christopher E.; Johnson, Christian D.; Lee, Brady D.

Iodine-129 (129I) generated at the U.S. Department of Energy (DOE) Hanford Site during plutonium production was released to the subsurface, resulting in several large, though dilute, plumes in the groundwater, including the plume in the 200-UP-1 operable unit (OU). Because 129I is an uncommon contaminant, relevant remediation experience and scientific literature are limited, though work is under way to better understand the fate and transport of 129I in the environment and the effectiveness of potential remediation technologies. The recent UP-1 Evaluation Plan for Iodine and report on the Conceptual Model of Iodine Behavior in the Subsurface at the Hanford Sitemore » provide information on the history of contamination in the 200-UP-1 OU, relevant controlling processes (biological and geochemical), risk, the conceptual site model, and potential remedial options, which provided a foundation for this study. In this study, available information was compiled and used to categorize potential remediation technologies, culminating in a recommendation of promising technologies for further evaluation. Approaches to improve the technical information about promising technologies are also recommended in this study so that a subsequent evaluation of potential remediation alternatives can assess these technologies.« less

Two methods for measuring Bell nonlocality via local unitary invariants of two-qubit systems in Hong-Ou-Mandel interferometers

NASA Astrophysics Data System (ADS)

Bartkiewicz, Karol; Chimczak, Grzegorz

2018-01-01

We describe a direct method to experimentally determine local two-qubit invariants by performing interferometric measurements on multiple copies of a given two-qubit state. We use this framework to analyze two different kinds of two-qubit invariants of Makhlin and Jing et al. These invariants allow us to fully reconstruct any two-qubit state up to local unitaries. We demonstrate that measuring three invariants is sufficient to find, e.g., the optimal Bell inequality violation. These invariants can be measured with local or nonlocal measurements. We show that the nonlocal strategy that follows from Makhlin's invariants is more resource efficient than local strategy following from the invariants of Jing et al. To measure all of the Makhlin's invariants directly one needs to use both two-qubit singlets and three-qubit W -state projections on multiple copies of the two-qubit state. This problem is equivalent to a coordinate system handedness measurement. We demonstrate that these three-qubit measurements can be performed by utilizing Hong-Ou-Mandel interference, which gives significant speedup in comparison to the classical handedness measurement. Finally, we point to potential applications of our results in quantum secret sharing.

Remedial investigation/feasibility study of the Clinch River/Poplar Creek Operable Unit. Volume 2. Biota and representative concentrations of contaminants. Appendixes A, B, C, D

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-03-01

This report presents the findings of an investigation into contamination of the Clinch River and Poplar Creek near the U.S. Department of Energy`s (DOE`s) Oak Ridge Reservation (ORR) in eastern Tennessee. For more than 50 years, various hazardous and radioactive substances have been released to the environment as a result of operations and waste management activities at the ORR. In 1989, the ORR was placed on the National Priorities List (NPL), established and maintained under the federal Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Under CERCLA, NPL sites must be investigated to determine the nature and extentmore » of contamination at the site, assess the risk to human health and the environment posed by the site, and, if necessary, identify feasible remedial alternatives that could be used to clean the site and reduce risk. To facilitate the overall environmental restoration effort at the ORR, CERCLA activities are being implemented individually as distinct operable units (OU`s). This document is the combined Remedial Investigation and Feasibility Study Report for the Clinch River/Poplar Creek OU.« less

Wetland survey of selected areas in the K-24 Site Area of responsibility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosensteel, B.A.; Awl, D.J.

1995-07-01

In accordance with DOE Regulations for Compliance with Floodplain/Wetlands Environmental Review Requirements, wetland surveys were conducted in selected areas within the K-25 Area of Responsibility during the summer of 1994. These areas are Mitchell Branch, Poplar Creek, the K-770 OU, Duct Island Peninsula, the Powerhouse area, and the K-25 South Corner. Previously surveyed areas included in this report are the main plant area of the K-25 Site, the K-901 OU, the AVLIS site, and the K-25 South Site. Wetland determinations were based on the USACE methodology. Forty-four separate wetland areas, ranging in size from 0.13 to 4.23 ha, were identified.more » Wetlands were identified in all of the areas surveyed with the exception of the interior of the Duct Island Peninsula and the main plant area of the K-25 Site. Wetlands perform functions such as floodflow alteration, sediment stabilization, sediment and toxicant retention, nutrient transformation, production export, and support of aquatic species and wildlife diversity and abundance. The forested, scrub-shrub, and emergent wetlands identified in the K-25 area perform some or all of these functions to varying degrees.« less

Accident D’Electrisation et Hemorragie Cerebro-Meningee : A Propos D’une Observation

PubMed Central

Chaibdraa, A.; Medjellakh, M.S.; Saouli, A.; Bentakouk, M.C.

2008-01-01

Summary L'électrisation est un évènement accidentel qui diffère des autres pathologies occasionnant des brûlures graves, à cause de ses spécificités qui traduisent d'une part la destruction du revêtement cutané, mais également les effets directs ou indirects du courant électrique sur tout tissu de l'organisme rencontré lors de son passage, en particulier le tissu nerveux. Les manifestations neurologiques centrales sont nombreuses, en relation avec les effets de l'électricité sur le parenchyme cérébral ou une lésion associée à l'électrisation. Nous rapportons l'observation d'une hémorragie cérébro-meningée survenant au 3ème jour d'une électrisation grave. Cette complication est bien documentée dans la littérature traitant des accidents d'électrisation post-foudroiement. N'ayant pas rencontré de cas similaire publié lors des accidents dus au courant industriel, nous présentons cette observation, qui soulève le problème du mécanisme physiopathologique de survenue, difficile à trancher. PMID:21991125

Technical/ administrative options for managing tritium MCL exceedances in P-area groundwater and Steel Creek

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ross, J.

2017-04-01

This white paper was requested by the Core Team (United States Department of Energy [USDOE], United States Environmental Protection Agency [USEPA], and South Carolina Department of Health and Environmental Control [SCDHEC]) at the P-Area Groundwater (PAGW) Operable Unit (OU) Scoping Meeting held in January 2017 to discuss recent data and potential alternatives in support of a focused Corrective Measures Study/Feasibility Study (CMS/FS). This white paper presents an overview of the problem, and a range of technical and administrative options for addressing the tritium contamination in groundwater and Steel Creek. As tritium cannot be treated practicably, alternatives are limited to mediamore » transfer, containment and natural attenuation principally relying on radioactive decay. Using other groundwater OU decisions involving tritium as precedent, Savannah River Nuclear Solutions (SRNS) recommends that final tritium alternatives be evaluated in a CMS/FS, understanding that the likely preferred remedy will include natural attenuation with land use controls (LUCs). This is based on the inability to significantly reduce tritium impact to Steel Creek using an engineered solution as compared to natural attenuation. The timing of this evaluation could be conducted concurrently with the final remedy evaluation for volatile organic compounds (VOCs).« less

Conjunctival lymphoma arising from reactive lymphoid hyperplasia.

PubMed

Fukuhara, Junichi; Kase, Satoru; Noda, Mika; Ishijima, Kan; Yamamoto, Teppei; Ishida, Susumu

2012-09-18

Extra nodal marginal zone B-cell lymphoma (EMZL) of the conjunctiva typically arises in the marginal zone of mucosa-associated lymphoid tissue. The pathogenesis of conjunctival EMZL remains unknown. We describe an unusual case of EMZL arising from reactive lymphoid hyperplasia (RLH) of the conjunctiva. A 35-year-old woman had fleshy salmon-pink conjunctival tumors in both eyes, oculus uterque (OU). Specimens from conjunctival tumors in the right eye, oculus dexter (OD), revealed a collection of small lymphoid cells in the stroma. Immunohistochemically, immunoglobulin (Ig) light chain restriction was not detected. In contrast, diffuse atypical lymphoid cell infiltration was noted in the left eye, oculus sinister (OS), and positive for CD20, a marker for B cells OS. The tumors were histologically diagnosed as RLH OD, and EMZL OS. PCR analysis detected IgH gene rearrangement in the joining region (JH) region OU. After 11 months, a re-biopsy specimen demonstrated EMZL based on compatible pathological and genetic findings OD, arising from RLH. This case suggests that even if the diagnosis of the conjunctival lymphoproliferative lesions is histologically benign, confirmation of the B-cell clonality by checking IgH gene rearrangement should be useful to predict the incidence of malignancy.

The Expected Cardiovascular Benefit of Plasma Cholesterol Lowering with or Without LDL-C Targets in Healthy Individuals at Higher Cardiovascular Risk.

PubMed

Cesena, Fernando Henpin Yue; Laurinavicius, Antonio Gabriele; Valente, Viviane A; Conceição, Raquel D; Santos, Raul D; Bittencourt, Marcio S

2017-06-01

There is controversy whether management of blood cholesterol should be based or not on LDL-cholesterol (LDL-c) target concentrations. To compare the estimated impact of different lipid-lowering strategies, based or not on LDL-c targets, on the risk of major cardiovascular events in a population with higher cardiovascular risk. We included consecutive individuals undergoing a routine health screening in a single center who had a 10-year risk for atherosclerotic cardiovascular disease (ASCVD) ≥ 7.5% (pooled cohort equations, ACC/AHA, 2013). For each individual, we simulated two strategies based on LDL-c target (≤ 100 mg/dL [Starget-100] or ≤ 70 mg/dL [Starget-70]) and two strategies based on percent LDL-c reduction (30% [S30%] or 50% [S50%]). In 1,897 subjects (57 ± 7 years, 96% men, 10-year ASCVD risk 13.7 ± 7.1%), LDL-c would be lowered from 141 ± 33 mg/dL to 99 ± 23 mg/dL in S30%, 71 ± 16 mg/dL in S50%, 98 ± 9 mg/dL in Starget-100, and 70 ± 2 mg/dL in Starget-70. Ten-year ASCVD risk would be reduced to 8.8 ± 4.8% in S50% and 8.9 ± 5.2 in Starget-70. The number of major cardiovascular events prevented in 10 years per 1,000 individuals would be 32 in S30%, 31 in Starget-100, 49 in S50%, and 48 in Starget-70. Compared with Starget-70, S50% would prevent more events in the lower LDL-c tertile and fewer events in the higher LDL-c tertile. The more aggressive lipid-lowering approaches simulated in this study, based on LDL-c target or percent reduction, may potentially prevent approximately 50% more hard cardiovascular events in the population compared with the less intensive treatments. Baseline LDL-c determines which strategy (based or not on LDL-c target) is more appropriate at the individual level. Há controvérsias sobre se o controle do colesterol plasmático deve ou não se basear em metas de concentração de colesterol LDL (LDL-c). Comparar o impacto estimado de diferentes estratégias hipolipemiantes, baseadas ou não em metas de LDL-c, sobre o risco de eventos cardiovasculares maiores em uma população de risco cardiovascular mais elevado. Foram incluídos indivíduos consecutivamente submetidos a uma avaliação rotineira de saúde em um único centro e que apresentavam um risco em 10 anos de doença cardiovascular aterosclerótica (DCVAS) ≥ 7,5% ("pooled cohort equations", ACC/AHA, 2013). Para cada indivíduo, foram simuladas duas estratégias baseadas em meta de LDL-c (≤ 100 mg/dL [Emeta-100] ou ≤ 70 mg/dL [Emeta-70]) e duas estratégias baseadas em redução percentual do LDL-c (30% [E30%] ou 50% [E50%]). Em 1.897 indivíduos (57 ± 7 anos, 96% homens, risco em 10 anos de DCVAS 13,7 ± 7,1%), o LDL-c seria reduzido de 141 ± 33 mg/dL para 99 ± 23 mg/dL na E30%, 71 ± 16 mg/dL na E50%, 98 ± 9 mg/dL na Emeta-100 e 70 ± 2 mg/dL na Emeta-70. O risco em 10 anos de DCVAS seria reduzido para 8,8 ± 4,8% na E50% e para 8,9 ± 5,2 na Emeta-70. O número de eventos cardiovasculares maiores prevenidos em 10 anos por 1.000 indivíduos seria de 32 na E30%, 31 na Emeta-100, 49 na E50% e 48 na Emeta-70. Em comparação com a Emeta-70, a E50% evitaria mais eventos no tercil inferior de LDL-c e menos eventos no tercil superior de LDL-c. As abordagens hipolipemiantes mais agressivas simuladas neste estudo, com base em meta de LDL-c ou redução percentual, podem potencialmente prevenir cerca de 50% mais eventos cardiovasculares graves na população em comparação com os tratamentos menos intensivos. Os níveis basais de LDL-c determinam qual estratégia (baseada ou não em meta de LDL-c) é mais apropriada para cada indivíduo.

Extracellular adenosine 5'-triphosphate concentrations changes in rat spinal cord associated with the activation of urinary bladder afferents. A microdialysis study.

PubMed

Rocha, Jeová Nina

2016-01-01

To determine adenosine 5'-triphosphate levels in the interstice of spinal cord L6-S1 segment, under basal conditions or during mechanical and chemical activation of urinary bladder afferents. A microdialysis probe was transversally implanted in the dorsal half of spinal cord L6-S1 segment in female rats. Microdialysate was collected at 15 minutes intervals during 135 minutes, in anesthetized animals. Adenosine 5'-triphosphate concentrations were determined with a bioluminescent assay. In one group of animals (n=7) microdialysate samples were obtained with an empty bladder during a 10-minutes bladder distension to 20 or 40cmH2O with either saline, saline with acetic acid or saline with capsaicin. In another group of animals (n=6) bladder distention was performed and the microdialysis solution contained the ectonucleotidase inhibitor ARL 67156. Basal extracellular adenosine triphosphate levels were 110.9±35.34fmol/15 minutes, (mean±SEM, n=13), and bladder distention was associated with a significant increase in adenosine 5'-triphosphate levels which was not observed after bladder distention with saline solution containing capsaicin (10µM). Microdialysis with solution containing ARL 67156 (1mM) was associated with significantly higher extracellular adenosine 5'-triphosphate levels and no further increase in adenosine 5'-triphosphate was observed during bladder distension. Adenosine 5'-triphosphate was present in the interstice of L6-S1 spinal cord segments, was degraded by ectonucleotidase, and its concentration increased following the activation of bladder mechanosensitive but not of the chemosensitive afferents fibers. Adenosine 5'-triphosphate may originate either from the central endings of bladder mechanosensitive primary afferent neurons, or most likely from intrinsic spinal neurons, or glial cells and its release appears to be modulated by capsaicin activated bladder primary afferent or by adenosine 5'-triphosphate itself. Determinar as concentrações extracelulares do 5'-trifosfato de adenosina no interstício dos segmentos medulares L6-S1, em condições basais ou durante a ativação mecânica e química das fibras aferentes vesicais. Um cateter de microdiálise foi implantado no sentido transversal na parte dorsal da medula espinal, entre os segmentos L6-S1 de ratas. O microdialisado foi coletado em intervalos de 15 minutos, durante 135 minutos, com os animais anestesiados. A concentração de 5'-trifosfato de adenosina nas amostras foi determinada mediante ensaio de bioluminescência. Em um grupo de animais (n=7), as amostras de microdialisado foram obtidas com a bexiga vazia, com distensão da bexiga para volume de 20 ou 40cmH2O, com solução salina, solução salina com ácido acético, ou solução salina com capsaicina. Em outro grupo (n=6), foi realizada com a bexiga distendida, e a solução para microdiálise continha o inibidor de ectonucleotidase ARL 67156. Os níveis extracelulares de trifosfato de adenosina no início do estudo foram 110,9±35,36fmol/15 minutos (média±EPM, n=13), e a distensão da bexiga causou um aumento nos níveis de 5'-trifosfato de adenosina, o que não foi observado após a distensão da bexiga com solução salina contendo capsaicina (10µM). A microdiálise com solução contendo ARL 67156 (1mM) foi associada com significante aumento dos níveis de trifosfato de adenosina extracelular, e nenhum aumento do trifosfato de adenosina foi observado durante a distensão da bexiga. O 5'-trifosfato de adenosina está presente no interstício do segmento L6-S1 da medula espinal, é degradado por ectonucleotidases, e sua concentração aumentou com a ativação das fibras aferentes mecanossensíveis da bexiga, mas não das quimiossensíveis. O 5'-trifosfato de adenosina pode ter sido liberado das terminações centrais dos neurônios aferentes primários mecanossensíveis ou, mais provavelmente, de neurônios espinais intrínsecos, ou ainda de células gliais. Sua liberação parece ser modulada por fibras aferentes primárias da bexiga ativadas pela capsaicina ou pelo próprio 5'-trifosfato de adenosina.

Prevalence of self-medication in Brazil and associated factors.

PubMed

Arrais, Paulo Sérgio Dourado; Fernandes, Maria Eneida Porto; Pizzol, Tatiane da Silva Dal; Ramos, Luiz Roberto; Mengue, Sotero Serrate; Luiza, Vera Lucia; Tavares, Noemia Urruth Leão; Farias, Mareni Rocha; Oliveira, Maria Auxiliadora; Bertoldi, Andréa Dâmaso

2016-12-01

To analyze the prevalence and associated factors regarding the use of medicines by self-medication in Brazil. This cross-sectional population-based study was conducted using data from the PNAUM (National Survey on Access, Use and Promotion of Rational Use of Medicines), collected between September 2013 and February 2014 by interviews at the homes of the respondents. All people who reported using any medicines not prescribed by a doctor or dentist were classified as self-medication practitioners. Crude and adjusted prevalence ratios (Poisson regression) and their respective 95% confidence intervals were calculated in order to investigate the factors associated with the use of self-medication by medicines. The independent variables were: sociodemographic characteristics, health conditions and access to and use of health services. In addition, the most commonly consumed medicines by self-medication were individually identified. The self-medication prevalence in Brazil was 16.1% (95%CI 15.0-17.5), with it being highest in the Northeast region (23.8%; 95%CI 21.6-26.2). Following the adjusted analysis, self-medication was observed to be associated with females, inhabitants from the North, Northeast and Midwest regions and individuals that have had one, or two or more chronic diseases. Analgesics and muscle relaxants were the therapeutic groups most used for self-medication, with dipyrone being the most consumed medicines. In general, most of the medicines used for self-medication were classified as non-prescriptive (65.5%). Self-medication is common practice in Brazil and mainly involves the use of non-prescription medicines; therefore, the users of such should be made aware of the possible risks. Analisar a prevalência e os fatores associados à utilização de medicamentos por automedicação no Brasil. Este estudo transversal de base populacional foi realizado com dados da Pesquisa Nacional de Acesso, Utilização e Promoção do Uso Racional de medicamentos (PNAUM), coletados de setembro de 2013 a fevereiro de 2014, por meio de entrevistas em domicílio. Todas as pessoas que referiram usar qualquer medicamento sem prescrição por médico ou dentista foram classificadas como praticantes de automedicação. Foram calculadas razões de prevalência bruta e ajustada (regressão de Poisson) e seus respectivos intervalos de confiança de 95% na investigação dos fatores associados ao consumo de medicamentos por automedicação. As variáveis independentes foram: aspectos sociodemográficos, de condições de saúde e de acesso e utilização de serviços de saúde. Adicionalmente, foram identificados os medicamentos mais consumidos por automedicação. A prevalência da automedicação no Brasil foi de 16,1% (IC95% 15,0-17,5), sendo maior na região Nordeste (23,8%; IC95% 21,6-26,2). Após análise ajustada, automedicação mostrou-se associada a ser do sexo feminino, pertencer às faixas etárias 10-19 anos, 20-29 anos, 40-59 anos e 60 anos ou mais, residir na região Norte, Nordeste ou Centro-Oeste, e ter uma ou duas ou mais doenças crônicas. Os analgésicos e os relaxantes musculares foram os grupos terapêuticos mais utilizados por automedicação, sendo a dipirona o fármaco mais consumido. No geral, a maioria dos medicamentos usados por automedicação foram classificados como isentos de prescrição (65,5%). A automedicação é prática corrente no Brasil e envolve, principalmente, o uso de medicamentos isentos de prescrição, devendo os usuários ficarem atentos aos seus possíveis riscos.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Daley, P F

The overall objective of this project is the continued development, installation, and testing of continuous water sampling and analysis technologies for application to on-site monitoring of groundwater treatment systems and remediation sites. In a previous project, an on-line analytical system (OLAS) for multistream water sampling was installed at the Fort Ord Operable Unit 2 Groundwater Treatment System, with the objective of developing a simplified analytical method for detection of Compounds of Concern at that plant, and continuous sampling of up to twelve locations in the treatment system, from raw influent waters to treated effluent. Earlier implementations of the water samplingmore » and processing system (Analytical Sampling and Analysis Platform, A A+RT, Milpitas, CA) depended on off-line integrators that produced paper plots of chromatograms, and sent summary tables to a host computer for archiving. We developed a basic LabVIEW (National Instruments, Inc., Austin, TX) based gas chromatography control and data acquisition system that was the foundation for further development and integration with the ASAP system. Advantages of this integration include electronic archiving of all raw chromatographic data, and a flexible programming environment to support development of improved ASAP operation and automated reporting. The initial goals of integrating the preexisting LabVIEW chromatography control system with the ASAP, and demonstration of a simplified, site-specific analytical method were successfully achieved. However, although the principal objective of this system was assembly of an analytical system that would allow plant operators an up-to-the-minute view of the plant's performance, several obstacles remained. Data reduction with the base LabVIEW system was limited to peak detection and simple tabular output, patterned after commercial chromatography integrators, with compound retention times and peak areas. Preparation of calibration curves, method detection limit estimates and trend plotting were performed with spreadsheets and statistics software. Moreover, the analytical method developed was very limited in compound coverage, and unable to closely mirror the standard analytical methods promulgated by the EPA. To address these deficiencies, during this award the original equipment was operated at the OU 2-GTS to further evaluate the use of columns, commercial standard blends and other components to broaden the compound coverage of the chromatography system. A second-generation ASAP was designed and built to replace the original system at the OU 2-GTS, and include provision for introduction of internal standard compounds and surrogates into each sample analyzed. An enhanced, LabVIEW based chromatogram analysis application was written, that manages and archives chemical standards information, and provides a basis for NIST traceability for all analyses. Within this same package, all compound calibration response curves are managed, and different report formats were incorporated, that simplify trend analysis. Test results focus on operation of the original system at the OU 1 Integrated Chemical and Flow Monitoring System, at the OU 1 Fire Drill Area remediation site.« less

Analyse chronometrique intersexes de la resolution de la tache d'horizontalite des liquides

NASA Astrophysics Data System (ADS)

Berthiaume, Francois

D'abondantes recherches ont demontre que la reussite a la tache d'horizontalite des liquides est en moyenne plus elevee chez les individus de sexe masculin que chez ceux de sexe feminin. Deux facteurs principaux ont ete proposes: il s'agit de la connaissance du principe physique de l'invariance de l'orientation des liquides et de certaines habiletes perceptives d'ordre visuel. Le but de la presente recherche est d'etablir la duree detaillee de la resolution de la tache d'horizontalite des liquides chez 185 filles et 180 garcons, ages de 15 a 19 ans et repartis en 8 groupes. Dans une version informatisee, le premier groupe trace la position de la surface de l'eau a l'interieur d'un contenant dans diverses inclinaisons et le deuxieme evalue si l'orientation d'une ligne y represente bien cette position; le troisieme groupe trace une horizontale dans un rectangle et le quatrieme juge si la ligne illustree y est bien horizontale. Quatre autres groupes executent respectivement les memes taches dans la version classique papier-crayon. Le temps accorde a la reflexion avant de commencer le trace, le temps de tracage comme tel et le temps de verification du trace complete sont calcules. Chez les groupes qui evaluent l'orientation d'une ligne sur support informatique, le temps requis pour y parvenir est note. Enfin, un questionnaire estime si les participants connaissent ou non le principe physique d'invariance de l'orientation de la surface d'un liquide. Les resultats revelent que cette connaissance est plus frequente chez les garcons dans l'ensemble des groupes. Dans le cas ou les sujets ont a tracer une ligne, les filles reussissent moins d'essais que les garcons s'il faut, sur support informatique, tracer la surface de l'eau dans un contenant incline ou a l'horizontale. Il en va de meme s'il faut, sur support papier, tracer une horizontale dans un contenant incline. Le trace de la surface de l'eau est plus exact chez les sujets connaissant le principe d'invariance et l'ecart intersexes disparait si l'analyse tient compte de cette connaissance. Sur le plan du temps de reponse, les deux sexes ne se distinguent que lors du trace de la surface de l'eau dans un contenant incline, les garcons reflechissant alors plus longtemps. Le temps mis a produire, puis a verifier un trace, ne differe pas selon le sexe des participants. Dans l'evaluation de l'orientation d'une ligne cependant, les filles ne se distinguent pas des garcons et les participants connaissant le principe d'invariance reussissent mieux que ceux l'ignorant. Par ailleurs, les filles procedent toujours moins rapidement que les garcons. Pour les contenants inclines ou a l'horizontale, si la ligne represente la surface de l'eau, la difference intersexes est annulee quand la connaissance du principe est prise en compte. (Abstract shortened by UMI.)

Research on large area VUV-sensitive gaseous photomultipliers for cryogenic applications

NASA Astrophysics Data System (ADS)

Coimbra, Artur Emanuel Cardoso

Desde cedo que a comunidade cientifica compreendeu que gases nobres em liquido sao excelentes meios de deteccao de radiacao, combinando a sua elevada densidade, elevado grau de homogeneidade e de elevado rendimento de cintilacao. Para alem destas caracteristicas inerentes, estes tem a potencialidade de fornecer ambos sinais de ionizacao - criando electroes livres - e cintilacao em resposta a interaccao com radiacao ionizante e, tendo em vista a sua aplicacao em experiencias de eventos raros relacionados com fisica de neutrinos ou materia-escura, a capacidade de autoblindagem garante a exclusao de eventos induzidos por radiacao de fundo. O facto de nao absorverem a sua propria luz, emergente dos eventos de cintilacao, permite a expansao deste tipo de detectores ate grandes volumes, sendo que as colaboracoes mais recentes propoem detectores com dezenas de toneladas de xenon em estado liquido. As experiencias actuais que usam gases nobres em estado liquido empregam xenon ou argon numa so fase (estado liquido) ou em dupla-fase (estado liquido + gasoso) e as suas aplicacoes abrangem desde as ja referidas experiencias de procura de eventos raros, passando por imagiologia medica tais como detectores de radiacao gama para PET ou câmaras Compton "3-gamma" em combinacao com PET, passando tambem por aplicacoes de seguranca como sistemas de inspeccao para deteccao de material fissil e, finalmente, em câmaras Compton para aplicacoes de astrofisica. Em ambas as configuracoes a leitura dos sinais de cintilacao e geralmente feita atraves de um grande numero de dispendiosos fotomultiplicadores de vacuo agrupados. A presente tese de doutoramento e dedicada aos fotomultiplicadores gasosos de grande area para aplicacoes criogenicas desenvolvidos no contexto do programa doutoral, tendo em vista a sua eventual aplicacao como um dispositivo complementar aos metodos existentes de deteccao de cintilacao, para aplicacao em futuras experiencias de grande escala. Esta pesquisa foi direccionada tendo em vista o desenvolvimento de eficientes fotomultiplicadores gasosos de grande area, potencialmente mais economicos por unidade de area, baseados em "Thick Gas-Electron Multipliers" (THGEMs). Combinando fotocatodos de alta eficiencia com multiplicadores gasosos de electroes capazes de atingir elevado ganho em carga obteve-se assim um dispositivo com elevada sensibilidade para a deteccao de fotoes unicos, com a possibilidade de discriminacao em posicao com resolucao espacial inferior a um milimetro e com resolucao temporal da ordem de poucos nano segundos. Contrariamente ao que sucede com a tecnologia de vacuo actualmente, com este dispositivo a localizacao em posicao de fotoes em grandes areas e feita num unico dispositivo integrando electronica habitualmente utilizada em experiencias de rastreamento de particulas. Neste trabalho o fotomultiplicador gasoso desenvolvido consiste numa cadeia de THGEMs combinados com um fotocatodo de iodeto de cesio (CsI) sensivel ao ultravioleta enquanto que os testes criogenicos foram realizados na Time Projection Chamber (TPC) de dupla fase de xenon liquido recentemente desenvolvida no Weizmann Institute of Science (WILiX). (Abstract shortened by ProQuest.).

Révision systématique des effets de la fréquence des repas en famille sur les résultats psychosociaux chez les jeunes

PubMed Central

Harrison, Megan E.; Norris, Mark L.; Obeid, Nicole; Fu, Maeghan; Weinstangel, Hannah; Sampson, Margaret

2015-01-01

Résumé Objectif Effectuer une révision systématique des effets de repas en famille fréquents sur les résultats psychosociaux chez les enfants et les adolescents et examiner s’il existe des différences dans les résultats selon le sexe. Sources des données Des études ont été cernées à la suite d’une recherche dans MEDLINE (de 1948 à la dernière semaine de juin 2011) et dans PsycINFO (de 1806 à la première semaine de juillet 2011) à l’aide de l’interface Ovide. Les expressions et mots clés MeSH utilisés seuls ou en combinaisons étaient les suivants : family, meal, food intake, nutrition, diets, body weight, adolescent attitudes, eating behaviour, feeding behaviour et eating disorders. Les bibliographies des articles jugés pertinents ont aussi été passées en revus. Sélection des études La recherche initiale a produit 1783 articles. Pour être incluses dans l’analyse, les études devaient répondre aux critères suivants : être publiées en anglais dans une revue révisée par des pairs; porter sur des enfants ou des adolescents; traiter de l’influence des repas en famille sur les paramètres psychosociaux (p. ex. consommation de drogues et autres substances, troubles de l’alimentation, dépression) chez les enfants ou les adolescents; avoir une conception d’étude appropriée, notamment des méthodes statistiques acceptables pour l’analyse des paramètres. Quatorze articles satisfaisaient aux critères d’inclusion. Deux examinateurs indépendants ont étudié et analysé les articles. Synthèse Dans l’ensemble, les résultats font valoir que la fréquence des repas en famille est inversement proportionnelle aux troubles de l’alimentation, à la consommation d’alcool et de drogues, aux comportements violents, aux sentiments de dépression ou aux pensées suicidaires chez les adolescents. Il existe une relation positive entre de fréquents repas en famille, une bonne estime de soi et la réussite scolaire. Les études révèlent des différences considérables dans les résultats chez les enfants et adolescents masculins et féminins, les sujets féminins ayant des résultats plus positifs. Conclusion Cette révision systématique vient confirmer davantage qu’il convient de préconiser de fréquents repas en famille. Tous les professionnels de la santé devraient renseigner les familles concernant les bienfaits de prendre régulièrement ensemble des repas.

Offset fémoral et le fonctionnement de la hanche dans la prothèse totale de la hanche

PubMed Central

Rachid, Abdelillah; Moncef, Erraji; Najib, Abbassi; Abdeljaouad, Najib; Abdelkarim, Daudi; Hicham, Yacoubi

2014-01-01

L'offset fémoral est l’élément pronostic le plus important dans l'arthroplastie de la hanche. Sa restauration est devenue de plus en plus une obligation. Toute modification de la valeur native de l'offset retenti sur la qualité du fonctionnement clinique de la hanche. Le but de notre travail était d’évaluer le fonctionnement clinique de la hanche en fonction de la valeur de l'offset fémoral après une arthroplastie. C'est une étude rétrospective effectuée entre 2010 et 2013, comportant 27 patients ayant bénéficiés d'une arthroplastie totale de la hanche. Les patients ayant eu un geste chirurgicale antérieur sur la même hanche ou sur la hanche controlatérale ont été exclus. Les mesures ont été effectuées sur des radiographies standards de la hanche en rotation interne d'environ 15°, avec un agrandissement à 100%. Les résultats cliniques étaient évalués au moyen du score de WOMAC qui était en moyenne de 15,2 points, et le score de Merle d'Aubigné-Postel avec une moyenne de 15 points. Deux autres tests ont été évalués dans notre étude qui sont le step et le hop test. Les meilleurs résultats fonctionnels ont été obtenus chez les patients ayant eu une latéralisation de la tige fémoral avec un offset augmenté. PMID:25400835

Temporal-spatial variation of bacterial diversity in estuary sediments in the south of Zhejiang Province, China.

PubMed

Lu, Xiao-Ming; Chen, Chang; Zheng, Tian-Ling; Chen, Jian-Jun

2016-03-01

The winter and summer microbial community structure in sediment samples obtained from the estuaries of the wastewater-polluted River Ou (DO and XO), River Feiyun (DF and XF), and River Ao (DA and XA) in the south of Zhejiang Province in China was determined using 454 pyrosequencing. Sediment samples (DD and XD) were also correspondingly collected near the shore far from the estuaries for comparison. For the above sediments, 294,870 effective sequences were obtained to do the bacterial diversity and abundance determination. In total, 1924, 1517, 2071, 1956, 1995, 1800, 2261, and 2097 operational taxonomic units were obtained at 3 % distance cutoff in the DO, XO, DF, XF, DA, XA, DD, and XD sediments, respectively. Bacterial phylotype richness in DD was higher than the other sediments, and XO had the least richness. The most dominant class in the DA, DD, DF, DO, and XA sediments is Gammaproteobacteria. Deltaproteobacteria is the most dominant one in XD, XO, and XF. Circa 14.4 % sequences in XD were found to be affiliated with the Flavobacteriales order. Characterization of the estuarine sediment bacterial communities indicated that chemical pollution has the potential to decrease the natural variability that exists among estuary ecosystems. However, chemical pollutants did not cause clear bio-homogenization in these estuaries.

Access to medicines for chronic diseases in Brazil: a multidimensional approach.

PubMed

Oliveira, Maria Auxiliadora; Luiza, Vera Lucia; Tavares, Noemia Urruth Leão; Mengue, Sotero Serrate; Arrais, Paulo Sergio Dourado; Farias, Mareni Rocha; Pizzol, Tatiane da Silva Dal; Ramos, Luiz Roberto; Bertoldi, Andréa Dâmaso

2016-12-01

To analyze the access to medicines to treat non-communicable diseases in Brazil according to socioeconomic, demographic, and health-related factors, from a multidimensional perspective. Analysis of data from the National Survey on Access, Use and Promotion of Rational Use of Medicines (PNAUM), household survey, sampling plan by conglomerates with representativeness of the Brazilian population and large areas of the country, according to sex and age domains. Data collected in 2013-2014 with sample of adults (≥ 20 years) who reported having non-communicable diseases and medical indication for use of medicines (n = 12,725). We assessed the prevalence of access to medicines for self-reported non-communicable diseases, considering four dimensions: availability, geographic accessibility, acceptability, and affordability. We applied Pearson's Chi-square test to assess the statistical significance of the differences between strata, considering the level of significance of 5%. We found prevalence of 94.3%, 5.2%, and 0.5% for full, partial, and null access, respectively. Higher prevalence was observed among seniors in the South compared to the Northeast; for those who reported having one non-communicable disease compared to those who reported having two or more; for those who needed one medicine compared to those who needed three or more; and for those who self-assessed their health as good or very good. Geographic accessibility was similar in the Unified Health System and in the private pharmacies (72.0%). Total availability of medicines was 45.2% in the Unified Health System, 67.4% in the Popular Pharmacy Program, and 88.5% in private pharmacies. Acceptability was 92.5% in the Unified Health System, 97.8% in the Popular Pharmacy Program, and 98.7% in private pharmacies. As to affordability, 2.6% of the individuals failed to take the medicines they should in the 30-day period prior to the interview due to financial difficulty. Prevalence of full access to medicines for non-communicable diseases in Brazil is high and presents significant differences for age group, region of the country, number of non-communicable diseases, and for medicines prescribed and self-assessment of health. The major barriers to access to medicines were identified in the dimensions analyzed. Analisar o acesso a medicamentos para tratar doenças crônicas não transmissíveis no Brasil segundo fatores socioeconômicos, demográficos e de saúde, sob perspectiva multidimensional. Análise de dados da Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos (PNAUM), inquérito domiciliar, plano amostral por conglomerados com representatividade da população brasileira e grandes regiões do País, segundo domínios de sexo e idade. Dados coletados em 2013-2014 com amostra constituída por adultos (≥ 20 anos) que referiram ter doenças crônicas não transmissíveis e indicação médica para usar medicamentos (n = 12.725). Avaliou-se a prevalência de acesso aos medicamentos para doenças crônicas não transmissíveis autorreferidas, considerando quatro dimensões: disponibilidade, acessibilidade geográfica, aceitabilidade e capacidade aquisitiva. Aplicou-se teste Qui-quadrado de Pearson para avaliar a significância estatística das diferenças entre os estratos, considerando o nível de significância de 5%. Foram encontradas prevalências de 94,3%, 5,2% e 0,5% para acesso total, parcial e nulo, respectivamente. Maiores prevalências ocorreram entre os idosos, na região Sul comparada à região Nordeste; naqueles que referiram ter uma doença crônica não transmissível comparados aos que referiram ter duas ou mais; naqueles que precisavam de um medicamento comparados aos que precisavam de três ou mais; e naqueles que autoavaliaram sua saúde como boa ou muito boa. A acessibilidade geográfica foi semelhante no Sistema Único de Saúde e nas farmácias privadas (72,0%). A disponibilidade total de medicamentos foi de 45,2% no Sistema Único de Saúde, 67,4% no Programa Farmácia Popular e 88,5% nas farmácias privadas. A aceitabilidade foi de 92,5% no Sistema Único de Saúde, 97,8% no Programa Farmácia Popular e 98,7% nas farmácias privadas. Quanto à capacidade aquisitiva, 2,6% dos indivíduos não tomou os medicamentos que deveria nos 30 dias anteriores à entrevista devido à dificuldade financeira. A prevalência do acesso total aos medicamentos para doenças crônicas não transmissíveis no Brasil é alta e apresenta diferenças significativas por faixa etária, região do País, número de doenças crônicas não transmissíveis e de medicamentos prescritos e autoavaliação da saúde. Foram identificadas as principais barreiras ao acesso a medicamentos nas dimensões analisadas.

Screening Protocol for the Electrochemical Characterization of Potential Supercapacitor Materials

DTIC Science & Technology

2009-11-01

Felix Wong; DRDC Atlantic TM 2009-279; R & D pour la défense Canada – Atlantique; Novembre 2009. Introduction ou contexte : Les forces armées ont... 13 Figure 10: The effect of active material... 13 : Typical Constant Current Charge-Discharge Curve for a 1.34 mg Electrode of PAni-2NSA/MWNT at a Constant Current of 0.2 mA

La peur de l'evaluation: evaluation de l'enseignement ou du sujet? (Fear of Evaluation: Evaluating the Teacher or the Subject?)

ERIC Educational Resources Information Center

Kosmidou-Hardy, Chryssoula; Marmarinos, Jean

2001-01-01

Addresses questions related to the evaluation of teachers, with specific attention to why there is such teacher resistance. Theorizes that it is the teachers' fear of evaluation of their personal identity rather than their professional competence that lies behind their resistance to evaluation. Calls for the use of action research as a basic…

New Schemes for Predictive Congestion Control

DTIC Science & Technology

1993-04-01

1 and that node j is the downstream neighbor of node i. With these changes, (3.1) becomes 2Ä,-,ou«(*) = 2Ri,^t(t - 1) - abias ;, (3.2) where biasi...estimate the value of Rjt<mt(t + 1): 2Rjtout(t + 1) = 2Rjt<mt(t) - abia ^-, (3.3) 18 where bias,- = (2RjtOUi(t)) lf2 — Bj(t). Again, the" notation

Genetically Modified Foods at the Intersection of the Regulatory Landscape and Constitutional Jurisprudence.

PubMed

Ghoshray, Saby

2015-01-01

An ecosystem...[y] ou always intervene and change something in it, but there's no way of knowing what all the downstream effects will be or how it might affect the environment. We have such a miserably poor understanding of how the organism develops from its DNA that I would be surprised if we don't get one rude shock after another.

Targeting PCNA Phosphorylation in Breast Cancer

DTIC Science & Technology

2012-04-01

inhibitor and dyes. These basic peptides and polycationic peptoids were labeled with fluorescein and used to assess the effect of structure on cellular... substitution of a peptoid conjugate that was synthesized during the project period. Additional types of analogs were prepared as well each providing...Broceta, A., Diezmann, F., Ou-Yang, C. Y., Fara, M. A. & Bradley, M. Synthesis, penetrability and intracellular targeting of fluorescein -tagged

Pharmacological Correction of the Human Functional State in High Altitude Conditions

DTIC Science & Technology

2001-06-01

Operational Medical Issues in Hypo-and Hyperbaric Conditions [les Questions medicales a caractere oprationel liees aux conditions hypobares ou hyperbares ...Cholesterol, Adaptation Paper presented at the RTO HFM Symposium on "Operational Medical Issues in Hypo- and Hyperbaric Conditions", held in Toronto...T.D., 1986, Recovery after Extreme Hypobaric Hypoxia as a Method of Study of Antihypoxic Activity of Chemical Compounds. In: Farmakologicheskaya

"O Ensaio como Forma" ou Um Ensaio acerca da Teoria Critica da Sociedade ("The Essay as Form" or An Essay about the Critical Theory of Society).

ERIC Educational Resources Information Center

Giordano, Rosely

2000-01-01

Illuminates the critical theory project, with themes permeating the theoretical constructions of Frankfurt (Germany). Debates the predominance of positivism in the production of knowledge. Speculates that "the essay as form" constitutes itself as a representation of the concept of the Enlightenment. Concludes with a dialogue between…

Advanced Structural Concepts for Weapons Storage - Flat and Mountainous Terrains.

DTIC Science & Technology

1983-06-01

be required in the Maintenance Area. 7. WATER AND WASTE WATER. Water supply and wastewater collection systems are assumed to be available. It is...Ufceooa w aWdoo.amwa.. ,FC.hc OU 0 coos a (Peoi...sa dooedhI "- llcrnIT ENmca46t 0 Coos c I de odk BLACK A VEATCH 0oevLU Soedly _______ ONAgmagO 0 . 1 5

Actes du colloque: Tendances actuelles de la recherche sur la langue parlee (Conference Presentations: Current Trends in Research on Oral Language).

ERIC Educational Resources Information Center

Auger, Julie, Ed.

Student papers presented at a sociolinguistics conference include: "La variation phonologique [d'une voyelle] a Hull"; "La force illocutoire des pronoms personnels 'je' et 'tu' en tant qu'insignes des places d'ou parlent les femmes et les hommes"; "L'emploi des modes indicatif et subjonctif dans le francais parle de la…

Vulnerability Assessment Using a Fuzzy Logic Based Method

DTIC Science & Technology

1993-12-01

evaluating computer security vulnerabilities is very labor intensive. To help ease this workload, this thesis presents two automated methods possibly...eal 3n, 0 e) 0 n It -f0 . nts reg"roreg Iths OU raen estre -tte In Vt )thef awfict Of this ~.,i~t 14,-, A I’ K1- 2 3" toe 17 %1d3.rV. ~ 0 C .~ Ats ,glt

Maritime NORAD: Setting a Course for Success in Joint, Interagency, and Bi-National Maritime Homeland Security and Defense

DTIC Science & Technology

2007-04-05

gauges to blueberries can have a radiation profile that is higher than normal background and, thus, alert the radiation pagers carried by boarding...illustrate how the defense away game can come directly to the homeland with little or no warning. R ou ti ne P at ro ls , I ns pe ct io ns & E

Stability Analysis of a Liquid Fuel Annular Combustion Chamber

DTIC Science & Technology

1979-11-01

FOREWORD This report summarizes a portion of the work done for NASA Grant NCR 4I3-0oU3-oj5. It Is thus masters research of the first author, Gary H... Flandro , G. A., "Resonant Combustion in Rockets," Scientific American, December 1960, pp. 95-103. 11 -0 Io U\\ U t APPENDICES 11 117 APPENDIX A ’,4

Le "tournoi des deux nations" ou une election legislative en France (The "Tournament of Two Nations" or a Legislative Election in France)

ERIC Educational Resources Information Center

Pucheu, Rene; And Others

1978-01-01

A presentation of the French electoral process in the form of a drama. The acts are: the rules of the game, the electoral laws; a short analysis of the "plot," the campaign; and an imaginary account of a campaign. The intention was more methodological than informative. (Text is in French.) (AMH)

Navy Personnel Research and Development Center Independent Research and Independent Exploratory Development Programs for FY 87.

DTIC Science & Technology

1988-04-01

also employed as a marketing and advertising consultant and did research and post doctoral studies at the University of Iowa and the University of...Phtior R I to decrcae’ In this example there is onlN one condition that could cause the r ,ult dCe, rib’,. I1 ou carefully examine de circuit and the po

Molecular Dynamics of Lipid Bilayers

DTIC Science & Technology

1989-08-09

34 ECZI~ NUMUER 01" O-USECNI’ONS) Vt5 DEGRLU: LOOEi-00(PICOSEC Z-ILIO Pfu .LC 2 I 2 Ni, I AlI I 1-.M U 1 l"M .111 p lPll..4 5~~~~ 93.U) i’(OU...Station Box 3944 Laramie, WY 82071 LINDSAY, Stuart M. RACKOVSKY, Shalom R. SINSKEY, Anthony J. Department of Physics Department of Biophysics

Industri-Plex, OU-1, Cover Certification Report, City of Woburn Rights of Way and Roads: September 30, 2008: Appendices E-K

EPA Pesticide Factsheets

2012-04-22

... EpA SW-846 (Third Edition) 1986 ... X."~~~k ••Y_••••~K_.*~,•r~K••••_•••W~_~~ ••• __ q_~~m ••• w~~_w ... 2-Me thy Ipheno l ~ 370 Fluoreno t-() 370 ...

Measuring Pilot Proficiency on an Instrument Training Maneuver

DTIC Science & Technology

1977-08-01

Psychological research on pilot training. Was--sngton, D. C.: Army Air Force Aviation Psychology Program, Research Report No. 8, 1947. Ericksen, S. C. A review...10 15 20 su m I S =. 24 S". **muz . Atars &f 300ft. of clim (Mappro&W~may 15300’) a&& at J.5W f t. Soabding P. Mmcav ad nmur4 thwouoww.c tb. &*ou 25 mvi

Achados incidentais de aneurismas torácicos e abdominais

PubMed Central

Góes, Adenauer Marinho de Oliveira; Mascarenhas, Bárbara Íris; Rodrigues, Sofia Cunha; de Andrade, Mariseth Carvalho; Franco, Reinaldo Sergio Monteiro

2016-01-01

Resumo Contexto Os aneurismas de aorta abdominal (AAAs) são os mais comuns. A incidência anual de ruptura do AAA é de oito casos por 100.000 habitantes. A detecção incidental pode beneficiar o paciente, desde que o diâmetro seja monitorado e o paciente receba o tratamento adequado. Objetivos Estimar a prevalência do diagnóstico incidental de aneurisma de aorta torácica (AAT) e de AAA em tomografias computadorizadas (TCs); avaliar a prevalência de sexo e idade dos pacientes e determinar quais as artérias acometidas e as características morfológicas dos aneurismas; determinar quais as indicações de TC mais associadas ao diagnóstico incidental de aneurismas. Métodos Estudo descritivo, retrospectivo e randomizado. Critérios de inclusão: pacientes com 50 anos ou mais submetidos a TC de tórax, abdome ou pelve. Critérios de exclusão: acompanhamento ou suspeita diagnóstica de aneurismas. Foram utilizados protocolos com questões sobre dados demográficos e anatômicos. Resultados Foram analisados 1.202 laudos radiológicos. Detectados 27 aneurismas (prevalência de 2,2%). Pacientes: 60% do sexo masculino e 40% do sexo feminino (p < 0,05). Localização: 13 casos (48,2%) na aorta ascendente (AAT); 7 (25,9%) na aorta infrarrenal (AAA); 2 (7,4%) aorta na transição toracoabdominal (ATA); 2 (7,4%) na ilíaca comum; 1 (3,7%) na ilíaca interna; 1 (3,7%) na artéria esplênica; e 1 (3,7%) na artéria renal. Conclusões A maioria dos pacientes foi do sexo masculino (60%); houve maior frequência de AAT (diâmetro médio de 4,1 cm), seguido de AAA (diâmetro médio de 4,0 cm) e ATA (diâmetro médio de 3,9 cm). A principal indicação para a realização de TC associada ao diagnóstico incidental de aneurismas foi em função de sintomas respiratórios. PMID:29930574

Les leishmanioses cutanées à Leishmania major et à Leishmania tropica au Maroc: aspects épidémio-cliniques comparatifs de 268 cas

PubMed Central

Chiheb, Soumia; Slaoui, Widad; Mouttaqui, Tarik; Riyad, Meriem; Benchikhi, Hakima

2014-01-01

Introduction Depuis 1995, le Maroc a connu une réactivation des foyers de leishmanioses cutanées (LC) à L. major et une nouvelle répartition géographique des foyers à L. tropica. Le but de cette étude est de comparer les aspects épidémio-cliniques associés aux LC potentiellement dûes à L. major et à L. tropica. Méthodes Une étude rétrospective a colligé 268 cas de LC au service de dermatologie du CHU Ibn Rochd de Casablanca entre Janvier 1995 et Septembre 2010. Les données étaient analysées par Epi info version 3.5.1. Le test X2 était appliqué (Différence significative = p< 0,05). Résultats Deux cent soixante-huit cas de LC ont été colligés, dont 160 femmes et 108 hommes. Ils ont été répartis en 123 patients originaires des foyers à L.major et 145 patients originaires des foyers à L. tropica. L'aspect ulcéronodulaire, ulcérovégétant ou végétant était retrouvé dans 58 cas (47,2%) des cas de LC à L. major versus 24 cas (16,7%) dans la L.C à L. tropica. L'aspect papulonodulaire était retrouvé dans 84 cas (58%) de LC à L. tropica contre 41 cas (33,3%) de LC à L. major. Conclusion Dans la LC à L. major, l'atteinte des membres et les aspects cliniques végétant ou ulcéro-végétant restent toujours prédominants. Dans la L.C à L. tropica, l'atteinte papulonodulaire unique du visage reste prédominante mais des formes ulcéronodulaires, végétantes ou ulcérovégétantes existent également dans les foyers récents à L. tropica, prêtant à confusion cliniquement avec des LC à L. major. PMID:25810796

Use of alcohol and other drugs among male university students and its meanings.

PubMed

Dázio, Eliza Maria Rezende; Zago, Márcia Maria Fontão; Fava, Silvana Maria Coelho Leite

2016-01-01

To understand the meanings that male university students assign to the condition of users of alcohol and other drugs. An exploratory study using a qualitative approach, with inductive analysis of the content of semi-structured interviews applied to 20 male university students from a public university in the southeast region of Brazil, grounded on the theoretical-methodological referential of interpretive anthropology and ethnographic method. Data were construed using content inductive analysis for two topics: use of alcohol and/or drugs as an outlet; and use of alcohol and/or other drugs: an alternative for belonging and identity. Male university students share the rules of their sociocultural environment that values the use of alcohol and/or other drugs as a way of dealing with the demands and stress ensuing from the everyday university life, and to build identity and belong to this social context, reinforcing the influence of culture. Compreender os significados atribuídos pelos universitários do sexo masculino à condição de usuários de álcool e outras drogas. Estudo exploratório de abordagem qualitativa, com análise de conteúdo indutiva de entrevistas semiestruturadas de 20 universitários do sexo masculino, matriculados em uma universidade pública da região sudeste do Brasil, fundamentado no referencial teórico-metodológico da Antropologia Interpretativa e do método etnográfico. Os dados foram interpretados com a análise de conteúdo indutiva em dois temas: O uso do álcool e/ou drogas como válvula de escape; O uso do álcool e/ou outras drogas: alternativa para o pertencimento e para a identidade. Os universitários do sexo masculino compartilham normas de seu meio sociocultural, que valorizam o uso de álcool e/ou outras drogas, como uma forma de lidar com as exigências e o estresse da vida universitária, criar uma identidade e ter pertencimento neste contexto social, reforçando a influência da cultura.

Coagulopathie aigue précoce des traumatismes crâniens graves: mortalité et facteurs pronostiques

PubMed Central

Hachimi, Abdelhamid; Elkhayari, Mina; Chaibi, Ibtissam; Razine, Rachid; Ziadi, Amra; Samkaoui, Mohamed Abdenasser

2014-01-01

Introduction Le but de ce travail était d'étudier la mortalité et les facteurs pronostiques de la Coagulopathie Traumatique (CoT) aigue précoce. Méthodes Il s'agissait d'une étude prospective sur 21 mois, incluant tous les traumatisés crâniens graves > 16 ans. Les données clinico-démographiques, biologiques et radiologiques ont été collectées à l'admission. La CoT a été définie par une thrombopénie < 120 000 /mm3 t/ou un Taux de Prothrombine (TP) < 70% et/ou un International Normalized Ratio (INR) > 1,3 et/ou un Temps de Céphaline Activé (TCA) > 40 sec. Résultats Nous avons colligé 69 patients ayant une CoT avec une médiane d'âge à 29 ans avec un intervalle interquartile à (23-41), et une prédominance masculine dans 87% des cas (60 patients). L'ISS médian à 56 avec un intervalle interquartile à (42-75). La mortalité était de 52,2% des cas (36 patients) suite à une souffrance cérébrale dans 74,3% des cas (26 patients). La durée médiane de séjour était de 10 jours avec un intervalle interquartile à (5-19). Les facteurs associés à la mortalité en analyse univariée étaient: le passager de véhicule, le délai de prise en charge, l'hématome sous dural aigu, l'AIS tête et l'ISS à l'admission; alors qu'en analyse multivariée c'étaient le délai de prise en charge (OR: 1,01; IC à 95%: 1,001-1,02) et l'ISS à l'admission (OR: 1,1; IC à 95%: 1,04-1,15) étaient des facteurs pronostiques indépendants. Conclusion L'amélioration du pronostic de ces patients repose essentiellement sur un développement de la médecine pré-hospitalière. PMID:25018842

Traduire encore Bertin aujourd'hui : pourquoi faire ? Les nouvelles faces cachées de la Sémiologie Graphique

NASA Astrophysics Data System (ADS)

Dhieb, Mohsen

2018-05-01

La « Sémiologie Graphique » de Bertin est un ouvrage majeur de la cartographie contemporaine. Cependant, dès sa parution en 1967, cet ouvrage a suscité autant d'intérêt que de méfiance : l'ouvrage n'était pas dans le « moule » de la littérature cartographique en vigueur. Pourtant, si plusieurs de ses principes et concepts fondateurs ont été adoptés, plusieurs autres ne sont pas bien passés ou n'ont pas été mis en pratique. Il y a comme un fossé entre certains énoncés théoriques de l'ouvrage et leur mise en pratique. Certaines affirmations de Bertin peuvent paraître obsolètes aujourd'hui à l'heure du numérique, comme la non prise en compte de l'aspect dynamique ou interactif de la carte. L'avènement récent des SIG, de la géomatique et des systèmes de Cartographie Assistée par Ordinateur a relégué les vieilles méthodes de traitement graphique de l'information au second rang. Dès lors pourquoi traduire encore aujourd'hui, à l'heure du numérique, la « Sémiologie Graphique » ? Justement, d'abord, parce que certains principes restent, en substance, peu connus ; plusieurs aspects demeurent encore à explorer ; certaines méthodes et techniques manuelles délaissées peuvent être revisitées et remises en marche grâce à la visualisation ; des innovations n'ont pas été expérimentées ou implémentées par les moyens numériques. Dans le monde arabe, peu de recherches se sont imprégnées de sémiologie graphique. Lors de la traduction de l'ouvrage en arabe, des points restés obscurs ont été décelés. Ce sont ces quelques idées et réflexions qui nous ont poussés à revivre cette formidable aventure.

Identification des objets et detection de leur alignement en utilisant la technologie RFID

NASA Astrophysics Data System (ADS)

Rahma, Zayoud

De nos jours, les vehicules motorises sont essentiels dans notre vie quotidienne, d'ou la necessite de leur approvisionnement en carburant. L'approvisionnement en carburant peut entrainer certains inconvenients, tels que: les files d'attente, la disponibilite non-continuelle du carburant et les fraudes. Les problemes d'attente et de disponibilite non-continuelle du carburant peuvent etre facilement resolus en allant a une autre station d'essence aux alentours si disponibles. Par contre le probleme de fraudes est plus difficile a resoudre. De ce fait, decoule notre solution qui consiste a developper un systeme intelligent pour la gestion d'approvisionnement en carburant afin de remedier a ce probleme de fraudes. Pour des raisons de surete, il faut eviter les risques d'etincelles dans l'environnement du carburant. En particulier, il convient de ne pas utiliser un systeme utilisant 1'electricite proche de la pompe, du tuyau ou du reservoir du carburant du vehicule. Nous avons choisi la technologie RFID (Radio Frequency IDentification) et avons opte pour l'utilisation des etiquettes passives, etant donne que les etiquettes semi-passives ou actives contiennent une batterie electrique et sont nettement plus cheres. Un vehicule motorise sera identifie avec une etiquette RFID passive collee au-dessus du goulot de son reservoir. Deux autres etiquettes RFID seront placees sur le pistolet de sorte que le flux du carburant ne sera autorise que lorsque les trois etiquettes sont alignees. Notre travail etait a la demande d'une entreprise petroliere ayant une chaine internationale de stations de carburant. Le travail consiste en la conception, par la recherche, du systeme requis et s'articule sur l'optimisation de la topologie des antennes et des etiquettes de sorte que le systeme juge qu'il y a alignement lorsque le bec du pistolet est fonce dans le goulot du reservoir, et par consequent autorise le versement du carburant. Dans tous les autres cas, le systeme doit juger qu'il n'y a pas alignement et par consequent le flux du carburant n'est pas autorise. Mots cles: RFID, identification, localisation, alignement, fraudes, station-service.

Sabemos prescrever profilaxia de tromboembolismo venoso nos pacientes internados?

PubMed Central

Lopes, Bruno Abdala Candido; Teixeira, Isabela Pizzatto; de Souza, Taynara Dantas; Tafarel, Jean Rodrigo

2017-01-01

Resumo Contexto Embora preconizada, a profilaxia de tromboembolismo venoso (TEV) deixa de ser realizada sistematicamente em pacientes internados. Objetivo Verificar se os pacientes hospitalizados recebem a prescrição correta da profilaxia de TEV do médico responsável por sua internação, conforme sua categoria de risco. Métodos Estudo transversal com análise de prontuários de pacientes internados no Hospital Santa Casa de Misericórdia de Curitiba, PR, entre 20 de março e 25 de maio de 2015. Excluíram-se os pacientes em uso de anticoagulantes ou com sangramento ativo. Analisou-se gênero, idade, tipo de cobertura de saúde, especialidade responsável pelo paciente e fatores de risco dos pacientes para classificá-los em alto, moderado ou baixo risco para TEV. Comparou-se o uso ou não da profilaxia entre as prescrições das especialidades clínicas e cirúrgicas, pacientes internados pelo Sistema Único de Saúde (SUS) e por convênios e de acordo com seu risco para TEV. Resultados Dos 78 pacientes avaliados, oito preencheram os critérios de exclusão. Dos 70 pacientes elegíveis (média etária 56,9 anos; 41 homens; 62 cobertos pelo SUS), 31 eram tratados por clínicos e 39 por cirurgiões. Apenas 46 (65,71%) pacientes receberam profilaxia para TEV. Dentre os pacientes clínicos, 29 (93,5%) receberam profilaxia, contra 17 (43,6%) do grupo cirúrgico (p < 0,001). Pacientes clínicos de moderado e alto risco receberam mais profilaxia que os cirúrgicos (p < 0,001 e p = 0,002). Não houve diferenças quanto à cobertura de saúde (SUS versus convênios médicos). Conclusões No Hospital Santa Casa de Misericórdia de Curitiba, pacientes cirúrgicos estão menos protegidos de eventos tromboembólicos em relação aos clínicos. PMID:29930647

Alcohol and drug use disorders, HIV status and drug resistance in a sample of Russian TB patients

PubMed Central

Fleming, M. F.; Krupitsky, E.; Tsoy, M.; Zvartau, E.; Brazhenko, N.; Jakubowiak, W.; E. McCaul, M.

2006-01-01

SUMMARY SETTING: Alcohol use, tuberculosis (TB) drug resistance and human immunodeficiency virus (HIV) risk behavior are of increasing concern in Russian TB patients. DESIGN: A prevalence study of alcohol use and HIV risk behavior was conducted in a sample of 200 adult men and women admitted to TB hospitals in St Petersburg and Ivanovo, Russia. RESULTS: Of the subjects, 72% were men. The mean age was 41. Active TB was diagnosed using a combination of chest X-ray, sputum smears and sputum cultures. Sixty-two per cent met DSM-IV criteria for current alcohol abuse or dependence. Drug use was uncommon, with only two patients reporting recent intravenous heroin use. There was one case of HIV infection. The mean total risk assessment battery score was 3.4. Depression was present in 60% of the sample, with 17% severely depressed. Alcohol abuse/dependence was associated with an eight-fold increase in drug resistance (OR 8.58; 95% CI 2.09-35.32). Patients with relapsing or chronic TB were more likely to meet the criteria for alcohol abuse/dependence (OR 2.56; 95% CI 1.0-6.54). CONCLUSION: Alcohol use disorders are common in patients being treated for active TB, and are associated with significant morbidity. Additional surveys are needed to examine the relationship between alcohol use disorders and anti-tuberculosis drug resistance. CONTEXTE: Chezles patients tuberculeux russes, l’utilisation d’alcool, la résistance aux médicaments antituberculeux et un comportement à risque pour le virus de l’immunodéficience humaine (VIH) sont des sujets croissants d’inquiétude. SCHÉMA: Une étude: de prévalence de l’utilisation d’alcool et du comportement à risque pour le VIH a été menée sur un échantillon de 200 hommes et femmes adultes, admis dans des hôpitaux pour la tuberculose (TB) de Saint-Pétersbourg et d’Ivanovo en Russie. RÉSULTATS: Il y avait 72% d’hommes dans l’échantillon. L’âge moyen est de 41 ans. On a diagnostiqué la TB active par l’emploi d’une combinaison du cliché thoracique, de la bacilloscopie et des cultures d’expectoration. Chez 62% des patients, les critères DSM-IV pour utilisation courante d’alcool ou pour dépendance étaient présents. L’utilisation de drogues est inhabituelle: deux patients seulement ont signalé une utilisation récente de l’héroïne par voie intraveineuse. Il n’y avait qu’un seul cas d’infection VIH. Le score total moyen de la batterie d’évaluation des risques a été de 3,4. Il y avait de la dépression chez 60% de 1’échantillon, dont 17% étaient en dépression sévère. L’utilisation ou la dépendance à l’égard de l’alcool étaient associées avec une multiplication par huit de la résistance aux médicaments (OR 8,58 ; IC95% 2,09-35,32). Les patients atteints de rechute de TB ou de TB chronique sont plus susceptibles de répondre aux critérés d’abus ou de dépendance de l’alcool (OR 2,56; IC95% 1,0-6,54). CONCLUSION: Les maladies liées à l’utilisation d’alcool sont fréquentes chez les patients traités pour TB active et sont associées à une morbidité significative. Des enquêtes complémentaires sont nécessaires pour examiner les relations entre les maladies liées à l’utilisation d’alcool et la résistance à l’égard des médicaments antituberculeux. MARCO DE REFERENCIA: El consumo de alcohol, la tuberculosis (TB) farmacorresistente y los comportamientos de riesgo para la infección por el virus de la inmunodeficiencia humana (VIH) constituyen una preocupación creciente en los pacientes con TB en la Fedéración de Rusia. MÉTODOS: Se llevó a cabo un estudio de prevalencia del consumo de alcohol y del comportamiento de riesgo para la infección por el VIH en una muestra de 200 adultos, hombres y mujeres, ingresados por TB en dos hospitales de San Petersburgo e Ivanovo en la Federación de Rusia. RESULTADOS: El 72% de los individuos fueron de sexo masculino. La media de la edad fue 41 años. El diagnóstico de TB activa se estableció mediante una combinación de criterios que incluyeron la radiografía de tórax y la baciloscopia y cultivo del esputo. El 62% de los individuos cumplió con los criterios diagnósticos de alcoholismo actual o dependencia al alcohol de la nomenclatura del DSM-IV. El consumo de drogas fue poco frecuente, pues sólo dos pacientes comunicaron uso intravenoso reciente de heroína. Se observó un caso de infección por el VIH. La media total obtenida con el cuestionario auto-administrado para evaluación de los comportamientos de riesgo para sida (risk assessment battery) fue 3,4. El 60% de los pacientes presentaron depresión y en 17% la depresión fue grave. El alcoholismo y la dependencia al alcohol se asociaron con una frecuencia ocho veces mayor de farmacorresistencia (OR 8,58; IC95% 2,09-35,32). Los pacientes con TB crónica o recaída tuvieron mayor probabilidad de cumplir con los criterios para alcoholismo y dependencia al alcohol (OR 2,56; IC95% 1,0–6,54). CONCLUSIÓN: Los trastornos por consumo de alcohol son frecuentes en pacientes tratados por TB activa y se asocian con una morbilidad considerable. Se precisan estudios adicionales para evaluar la relación entre estos trastornos y la resistencia a los medicamentos antituberculosos. PMID:16704041

Queda dos homicídios em São Paulo, Brasil: uma análise descritiva

PubMed Central

Peres, Maria Fernanda Tourinho; Vicentin, Diego; Nery, Marcelo Batista; de Lima, Renato Sérgio; de Souza, Edinilsa Ramos; Cerda, Magdalena; Cardia, Nancy; Adorno, e Sérgio

2012-01-01

Objetivo Descrever a evolução da mortalidade por homicídios no Município de São Paulo segundo tipo de arma, sexo, raça ou cor, idade e áreas de exclusão/inclusão social entre 1996 e 2008. Métodos Estudo ecológico de série temporal. Os dados sobre óbitos ocorridos no Município foram coletados da base de dados do Programa de Aprimoramento das Informações sobre Mortalidade, seguindo a Classificação Internacional de Doenças, Décima Revisão (CID-10). Foram calculadas as taxas de mortalidade por homicídio (TMH) para a população total, por sexo, raça ou cor, faixa etária, tipo de arma e área de exclusão/inclusão social. As TMH foram padronizadas por idade pelo método direto. Foram calculados os percentuais de variação no período estudado. Para as áreas de exclusão/inclusão social foram calculados os riscos relativos de morte por homicídio. Resultados As TMH apresentaram queda de 73,7% entre 2001 e 2008. Foi observada redução da TMH em todos os grupos analisados, mais pronunciada em homens (−74,5%), jovens de 15 a 24 anos (−78,0%) e moradores de áreas de exclusão social extrema (−79,3%). A redução ocorreu, sobretudo, nos homicídios cometidos com armas de fogo (−74,1%). O risco relativo de morte por homicídio nas áreas de exclusão extrema (tendo como referência áreas com algum grau de exclusão social) foi de 2,77 em 1996, 3,9 em 2001 e 2,13 em 2008. Nas áreas de alta exclusão social, o risco relativo foi de 2,07 em 1996 e 1,96 em 2008. Conclusões Para compreender a redução dos homicídios no Município, é importante considerar macrodeterminantes que atingem todo o Município e todos os subgrupos populacionais e microdeterminantes que atuam localmente, influenciando de forma diferenciada os homicídios com armas de fogo e os homicídios na população jovem, no sexo masculino e em residentes em áreas de alta exclusão social. PMID:21390415

Prévalence et caractéristiques des effets indésirables des antihypertenseurs chez les patients suivis en ambulatoire au Centre Hospitalier Universitaire Yalgado Ouédraogo

PubMed Central

Millogo, Georges Rosario Christian; Zongo, Ragomzingba Frank Edgard; Benao, Anita; Youl, Estelle Noëla Hoho; Bassoleth, Blaise Alexandre Bazona; Ouédraogo, Moussa; Zabsonré, Patrice; Guissou, Innocent Pierre

2018-01-01

La prise en charge médicamenteuse de l'hypertension artérielle (HTA) entraine des effets indésirables qui peuvent être gênants et ainsi influencer l'observance du patient. Nous avons étudié ces effets indésirables dans le service de cardiologie du Centre hospitalier universitaire Yalgado Ouédraogo afin de déterminer leurs fréquences et leurs caractéristiques. Il s'agissait d'une étude transversale de juillet à septembre 2015 chez les patients suivis en ambulatoire pour HTA. Les données ont été obtenues à partir de l'interrogatoire, des carnets de suivi des patients et des fiches de consultations. Au total 278 patients ont été inclus. La population d'étude incluait 69,1% de femmes. L'âge moyen était de 52,2 ans avec des extrêmes de 23 et 86 ans. Quatre vingt et sept virgule huit pourcent (87,8%) vivaient en milieu urbain. Le tabagisme, la dyslipidémie et les antécédents familiaux d'HTA représentaient respectivement 9%, 35,6% et 57,2%. Au plan thérapeutique, 43,2% étaient sous monothérapie, 35,6% sous bithérapie à l'initiation du traitement. Les inhibiteurs calciques (59,7%) étaient la classe thérapeutique la plus utilisée. La prévalence globale des effets indésirables était de 60,1%. Les inhibiteurs calciques étaient impliqués dans 53,6% suivis des diurétiques (48,6%) dans la survenue de l'effet indésirable. La prévalence spécifique par molécule était 28,1% pour l'amlodipine et 24,5% pour l'hydrochlorothiazide. La diurèse excessive (13,7%), la toux (12,9%) et les vertiges (11,5%) étaient les effets indésirables les plus fréquemment évoqués par les patients. Le système nerveux central et périphérique et le système ostéo-musculaire étaient les systèmes les plus atteints. Les effets indésirables sont un déterminant majeur de l'adhésion aux traitements antihypertenseur, car leur impact sur la vie quotidienne des patients peut s'avérer significatif. PMID:29875965